gebhart/patrepeval huggingface dataset:
The Synthesis and Luminescence Quenching of the Water-soluble Polymer-supported Tris(2,2′-bipyridine)ruthenium(II) Analogue (1982)

Abstract The p-aminostyrene-N-vinylpyrrolidone copolymer-supported tris(2,2′-bipyridine)ruthenium(II) analogue, [Ru(bpy)2(pbyCOOH)]2+ (bpy=2,2′-bipyridine and pbyCOOH=polymeric bipyridine ligand), has been prepared, and the luminescence behavior of the polymer complex has been investigated in an aqueous solution. The efficiency of the quenching of the excited state of the polymer complex with [Fe(CN)6]4−, [Co(phen)3]2+, and Cu2+ is compared with that of [Ru(bpy)3]2+. The quenching of the excited state of the polymer complex by Cu2+ is strongly enhanced by the effect of the polymer chains. In the polymer complex/Cu2+ system, the quenching by Cu2+ in the presence of poly(p-styrenesulfonate) is much more effective than in the absence of the polyion. The characteristics of the polymer complex in terms of the luminescence behavior are discussed.
Effect of the Histamine H2-receptor Antagonist, Cimetidine, on Gastric Secretion and Serum Gastrin during Insulin Infusion in Man (1976)

Carter, D. C., Forrest, J. A. H., Logan, R. A., Ansell, I., Lidgard, G., Heading, R. C. & Shearman, D. J. C. Effect of the histamine H2-receptor antagonist, cimetidine, on gastric secretion and serum gastrin during insulin infusion in man. Scand. J. Gastroent. 1976, 11, 565-570Cimetidine infusion (100 mg h-1) reduced the acid secretory response to insulin infusion (0.03 units Kg-1h-1) when compared to paired control tests in 6 healthy volunteers. There was no significant difference between cimetidine and control tests in terms of pepsin output or serum gastrin concentrations. Cimetidine also reduced the acid secretory response when administered after 90 minutes of insulin had established a secretory response in extended tests in 3 additional volunteers. Cimetidine may have therapeutic potential in the peptic ulcer diathesis.
Rare Variants in Cardiomyopathy Genes Associated With Stress-Induced Cardiomyopathy (2015)

CADD, Combined Annotation Dependent DepletionFPKM, fragments per kilobase pair of exon per million fragments mappedNHLBI GO ESP, National Heart, Lung, and Blood Institute Grand Opportunity Exome Sequencing ProjectPCR, polymerase chain reactionSIC, stress-induced cardiomyopathy.
EEG spectral entropy correlates with regional cerebral blood flow during sevoflurane and propofol anaesthesia (2005)

Maksimow, A.1; Kaisti, K.2; Aalto, S.3; Mäenpää, M.4; Jääskeläinen, S.5; Hinkka, S.6; Martens, S.7; Särkelä, M.7; Viertiö-Oja, H.7; Scheinin, H.1 Author Information
On the impacts of low rate DoS attacks on VoIP traffic (2008)

Abstract Low rate TCP DoS (Shrew) and reduction of quality (RoQ) attacks have been proven to be detrimental to TCP traffic in the Internet. In this paper, we investigate the effect of these attacks on QoS sensitive, real time UDP traffic, like VoIP. Both of these attacks are difficult to detect, as the average attack traffic is low. These stealthy RoQ attacks are especially hard to detect as their periodicity is not well‐defined, and the attacks can contain spoofed source as well as destination IP addresses. Extensive ns2 simulations have been performed under realistic scenarios to validate the effects of these attacks on real time VoIP traffic using the G711 and G729a audio codecs. Forward Error Correction (FEC) is also considered in our analysis to recover packets from the packet loss caused by attacks. Without FEC, these attacks can drastically reduce the quality of VoIP traffic, leading to denial of service. To evaluate the perceptual quality of voice under attacks, the network losses are mapped to user's quality perception by using the ITU E‐model. The MOS range of the E‐model decreases from best to medium due to the low rate TCP DoS and RoQ attacks even when FEC is deployed. In some of the attack scenarios, the packet losses are bursty, which can lead to dropped calls. In addition, the stealthy RoQ attacks with higher burst lengths are as effective as the shrew attack in impairing VoIP traffic. We have also evaluated the effects of the attack on the VoIP traffic on the DETERLAB testbed, which has specifically been built for conducting network security research, and the results are consistent with the ns2 simulation results. We believe our investigation is important to remove the misconception about low rate TCP DoS and RoQ attacks that they affect only TCP traffic in the Internet. Copyright © 2008 John Wiley &amp; Sons, Ltd.
Enhanced electrophoretic resolution of monosulfate glycosaminoglycan disaccharide isomers on poly(methyl methacrylate) chips (2007)

To improve the separation of monosulfate glycosaminoglycan disaccharide isomers by microchip electrophoresis, we found that addition of 1,4-dioxane (DO) dramatically improved analyte resolution, probably due to solvation effects. Methylcellulose (MC) was tested for the ability to suppress EOF and analyte adsorption to the chip. To improve analyte resolution, buffer pH, beta-CD, and DO were systematically investigated. Fast separation was achieved by increasing the electric field strength, and field-amplified sample stacking occurred with increasing buffer concentrations. Therefore, based on our findings, we describe an efficient method for the separation of monosulfate and trisulfate unsaturated disaccharides (DeltaDi-UA2S, DeltaDi-4S, DeltaDi-6S, and DeltaDi-triS) derivatized with 2-aminoacridone hydrochloride. A mixture of monosulfate disaccharide isomers (DeltaDi-UA2S, DeltaDi-4S, and DeltaDi-6S) was baseline-separated within 75 s on a poly(methyl methacrylate) chip using a mixed buffer (DO/running buffer 57:43 v:v), 0.5% MC, pH 6.81, with an E(sep) of 558 V/cm. The theoretical plate was in the range of 5 x 10(5) to 1 x 10(6) m-1.
HRS Instability in Oxide-Based Bipolar Resistive Switching Cells (2020)

One of the key challenges in the reliability of valence change [valence change-based memory (VCM)] resistive switching random access memories (ReRAMs) is the short-term instability of the programed state. Due to read noise, program verify or shaping algorithms are ineffective and read current (or resistance) distributions always revert to their intrinsic statistics. In this work, we analyze the instability of the high resistive state (HRS) measured on ZrO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> -based devices via Factorial Hidden Markov Models. The extracted current jumps are explained by distinct ionic jumps via physics-based kinetic Monte Carlo (KMC) models. The simulation results reveal jumps of oxygen vacancies from the densely packed filament (plug) region to a sparsely packed gap (disc) region as origin of the most critical, large current jumps. These findings are used to extend our compact model (JART v1b) by a read noise module. We demonstrate simulated HRS instability in excellent agreement with our experimental data. Whereas the KMC approach provides a physical understanding of the processes underlying the HRS instability, the compact model enables the simulation of read noise up to industrially relevant array scales.
Sensor Noise Caused by Vibrations of Flaw Detection Probe Generated in Helical Heating Tubes in a Fast Breeder Reactor and Its Countermeasures (3rd, Report, Parameter Study by Numerical Simulations) (2006)

An eddy current testing (ECT) probe is used for a diagnosis of a helical heating tube installed in a fast breeder reactor, and a vibration of ECT probe makes the diagnosis difficult. In our previous report, we proposed an analytical model of the ECT probe incorporating with a fictional force and confirmed that the vibration was caused by Coulomb friction. In this paper, it is shown that numerical simulations utilizing the analytical model agree with various experimental results of the vibration of ECT probe, so that the reliability of the analytical model and the numerical simulation is increased. It follows that a preceding estimation of the vibration is available by the numerical simulation. Based on a behavior of the entire probe, which is obtained by the numerical simulation, we discuss a countermeasure to suppress the probe vibration. The validity of countermeasure is demonstrated through the numerical simulations.
variable frequency microwave excited plasma (1995)

Summary form only given, as follows. This paper reports on the use of an agile frequency source in generating plasma. A traveling wave tube (TWT) provides approximately one octave bandwidth and variable power level up to 2 KW. By controlling the frequency, efficient coupling to the load (materials and/or plasma) can be maintained even as the load is changing in properties or position. Furthermore, the variable frequency power source allows the localization of the plasma discharge in precise areas of interest to specific processes. The excitation frequencies can be continuously swept to scan the plasma across an arbitrary-shaped target surface. Plasma generation and position control is reviewed and experimental results on variable frequency microwave excited plasma are presented.
Multi-channel access in wireless networks using interference-aware channel segregation based dynamic channel assignment (2013)

The co-channel interference (CCI) limits the capacity of wireless networks due to the limited number of available channels and the fact that the same channel must be reused in the system. Recently, we proposed the interference-aware channel segregation based dynamic channel assignment (IACS-DCA). Stable channel reuse pattern can be formed in a distributed manner which can minimize the CCI experienced at access points (APs) or base stations (BSs). In this paper, we introduce a multi-channel access technique for the IACS-DCA. Each AP has channel priority table, in which the channels are listed by the ascending order of average CCI power. Original IACS-DCA assumes the single channel access using the first priority channel with the lowest average CCI power. By using multiple channels at the same time in the descending priority order, more number of users can access an AP. However, the use of channels below the first orders at the same time increases the CCI and may make the channel reuse pattern unstable. We examine, by computer simulation, the channel reuse pattern and confirm that the IACS-DCA improves the signal-to-interference power ratio (SIR) even with multi-channel access compared to the conventional quasi-DCA using multi-channel access.
Novel dynamic flow allocation scheme over ethernet passive optical networks (2007)

A new dynamic flow allocation scheme to guarantee quality of service and more stabilized performance is proposed, replacing an Ethernet passive optical network. This new scheme improves a priority-based access network, converting it to a flow-based access network with a new access mechanism and scheduling algorithm. With this new scheme, a network service provider can provide upper limits of transmission delays by the flow. The modeling and simulation results with mathematical analyses obtained by this scheme are also provided.
A Novel Contamination Free Two Temperature Continuous Flow Polymerase Chain Reactor (2007)

Polymerase Chain Reaction (PCR) is an enzymatic process that has dramatically advanced many fields of life sciences, where it is an indispensable tool in a burgeoning range of applications, including diagnostic medicine, molecular biology, forensics and food testing. Recent increased demand for extremely high throughput PCR systems has led to the development of miniaturised continuous flow microfluidic PCR devices, which may have extremely high throughput compared to standard commercial PCR thermal cyclers. A novel continuous flow microfluidic PCR device has been designed and fabricated, consisting of two thermal zones maintained on aluminium thermal blocks providing the precise temperatures required for denaturation and annealing/extension. Polycarbonate sideplates retain the denaturation thermal block vertically above the annealing/extension thermal block while allowing for a variable air gap to be maintained between them. Heating of the denaturation thermal block is achieved using a Labview controlled Thermofoil heater, while the annealing/extension thermal block is maintained at temperature by optimised heat transfer from the denaturation block. Flow-through capillary tubing is positioned into a grooved serpentine channel machined into these thermal blocks. This serpentine channel passes through each thermal block fifty times, providing fifty PCR thermal cycles. Contamination free high throughput continuous flow PCR necessitates that the samples be encapsulated in an immiscible carrier fluid to eradicate cross contamination between samples and suppress the likelihood of the sample contacting the capillary leading to sample degradation. Encapsulation of the PCR reaction mixture is achieved upstream of the thermal cycler through segmentation of the sample into droplets entrained within an immiscible carrier fluid, which are then cycled through the thermal cycler. High throughput DNA amplification of two genes, GAPDH and LEF1, from the REH cell line has been successfully demonstrated on this microfluidic platform without any detectable contamination between samples. The PCR droplet reactors were approximately 250nl which is two orders of magnitude less than the standard sample size for most commercial PCR thermal cyclers.
OCEAN (2014)

Recent process technology advances trigger reliability issues that degrade the Quality-of-Service (QoS) required by embedded Systems-on-Chip (SoCs). To maintain the required QoS with acceptable overheads, we propose OCEAN, a novel cross-layer error mitigation. OCEAN enforces on-chip SRAMs reliability with a fault-tolerant buffer. We utilize this buffer to protect a portion of the processed data used to restore from runtime error. We optimally select the buffer size to minimize the energy overhead, with timing and area constraints. OCEAN achieves full error mitigation with 10.1% average energy overhead compared to base-line operation that does not include any error correction capability, and 65% energy savings, compared to a cross-layer error mitigation mechanism.
System Co-Design Modeling Methodology of a High Speed (25Gbps) Multi-Rate 4-Channel Retimer: Simulation to Measurement Correlation (2018)

Abstract In this paper we detail the system (viz. silicon-package-pcb) electrical co-design of a 130nm BiCMOS high-speed (25Gbps) 4-channel multi-rate retimer, packaged in a small 6-mm × 6-mm FC BGA package, with integrated advanced signal conditioning circuitries. Electrical optimization of the silicon-package-pcb over the high speed channels, to achieve desired performance, was achieved through a coupled circuit-to-electromagnetic co-design modeling and simulation methodology. Key figure of merits for system electrical performance (viz. insertion loss, return loss, crosstalk/isolation, jitter, and power supply inductance and resistance parasitics, among others) are modeled and analyzed. Laboratory measurements on a retimer are presented that validate the integrity of the modeling methodology. Good correlation between modeling methodology and laboratory measurements is achieved.
Cutting Edge: Bystander Apoptosis Triggers Dendritic Cell Maturation and Antigen-Presenting Function (1998)

Abstract Physiologic cell death via apoptosis occurs without inflammation or autoimmunity. Here, we investigated the outcome of the interaction of apoptotic cells with dendritic cells (DCs), which are potent professional APCs. DCs internalized apoptotic cells and processed them for presentation to both MHC class I- and class II-restricted T cells with an efficiency that was dependent upon the number of apoptotic cells. The latter event was accompanied by the autocrine/paracrine secretion of IL-1β and TNF-α, with eventual DC maturation. High numbers of apoptotic cells, mimicking a failure of their in vivo clearance, are therefore sufficient to trigger DC maturation and the presentation of intracellular Ags from apoptotic cells, even in the absence of exogenous “danger” signals.
Optical neurochip with learning capability (1992)

A dynamic optical neurochip with variable synaptic interconnection capability has been reported. A novel type of photodetector called a variable sensitivity photodetector has been developed for the synaptic interconnection of neural networks. It utilizes a metal-semiconductor-metal structure whose quantum efficiency can be modulated by an applied bias voltage. The fabricated dynamic optical neurochip consists of an 8*8 variable sensitivity photodetector (VSPD) array and an 8 line-shaped LED array. It is shown that this device is suitable for learning in neural networks. The application to pattern classification is demonstrated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Carbon monoxide hydrogenation using cobalt manganese oxide catalysts: initial catalyst optimization studies (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarbon monoxide hydrogenation using cobalt manganese oxide catalysts: initial catalyst optimization studiesSaul Colley, Richard G. Copperthwaite, Graham J. Hutchings, and Mark Van der RietCite this: Ind. Eng. Chem. Res. 1988, 27, 8, 1339–1344Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/ie00080a001https://doi.org/10.1021/ie00080a001research-articleACS PublicationsRequest reuse permissionsArticle Views480Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Dual D2-Receptor and β2-Adrenoceptor Agonists for the Treatment of Airway Diseases. 1. Discovery and Biological Evaluation of Some 7-(2-Aminoethyl)- 4-hydroxybenzothiazol-2(3H)-one Analogues (1998)

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTDual D2-Receptor and β2-Adrenoceptor Agonists for the Treatment of Airway Diseases. 1. Discovery and Biological Evaluation of Some 7-(2-Aminoethyl)- 4-hydroxybenzothiazol-2(3H)-one AnaloguesRoger V. Bonnert, Roger C. Brown, David Chapman, David R. Cheshire, John Dixon, Francis Ince, Elizabeth C. Kinchin, Amanda J. Lyons, Andrew M. Davis, Catherine Hallam, Stephen T. Harper, John F. Unitt, Iain G. Dougall, Dale M. Jackson, Kenneth McKechnie, Alan Young, and Wilfred T. SimpsonView Author Information Astra Charnwood, Bakewell Road, Loughborough, Leicestershire LE11 5RH, U.K. Cite this: J. Med. Chem. 1998, 41, 25, 4915–4917Publication Date (Web):November 13, 1998Publication History Received16 July 1998Published online13 November 1998Published inissue 1 December 1998https://pubs.acs.org/doi/10.1021/jm980421fhttps://doi.org/10.1021/jm980421frapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views596Altmetric-Citations44LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Agonists,Amines,Nitrogen,Receptors,Substituents Get e-Alerts
The Relationship of Alpha1‐Antitrypsin to Inflammatory Periodontal Disease, (1979)

Alpha1-antitrypsin (alpha1-AT) is a serum protease inhibitor with a well established role in bodily defense against destructive inflammatory diseases. alpha1-AT exhibits inheritable genetic polymorphism (Pi types). Certain Pi types have been shown to predispose to emphysema and, in this study, also appear to be related to increased chronic periodontitis susceptibility.
A long range restriction map of the pseudoautosomal region by partial digest PFGE analysis from the telomere (1988)

The analysis of partial digestion products extending from the telomere of the human X and Y chromosomes, visualised by hybridisation to a probe located close to the telomere, was used to establish a restriction map of the pseudoautosomal region. In this highly polymorphic region with a 10-fold elevated recombination frequency in males we identified site or methylation differences between 7 different in male and female cell lines and tissues, and derived an estimate of the size of the pseudoautosomal region of approximately 3 Megabases by comparing X and Y chromosomes. This size correlates well with previous estimates based on genetic arguments and argues against a strongly enhanced rate of exchange near telomeres in general. We identified a CpG rich and hypomethylated region within 500 kbp from the telomere, which might reflect structural features of mammalian telomeres, and a small number of (additional) CpG islands, which might represent candidate genes for the Turner phenotype in XO females.