gebhart/patrepeval huggingface dataset:
TERAHERTZ SUBWAVELENGTH STRUCTURES FOR SENSING AND NDE (2010)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation N. Gopalsami, A. Heifetz, H. T. Chien, A. C. Raptis; TERAHERTZ SUBWAVELENGTH STRUCTURES FOR SENSING AND NDE. AIP Conference Proceedings 22 February 2010; 1211 (1): 557–563. https://doi.org/10.1063/1.3362443 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Precompensation for anticipated erasures in LTI interpolation systems (2005)

This paper considers compensation of anticipated erasures in a discrete-time (DT) signal such that the desired interpolation can still be accomplished, with minimum error, through a linear time-invariant (LTI) filter. The algorithms presented may potentially be useful in the compensation of a fault in a digital-to-analog converter where samples are dropped at known locations prior to reconstruction. Four algorithms are developed. The first is a general solution that, in the presence of erasures, minimizes the squared error for arbitrary LTI interpolation filters. In certain cases, e.g., oversampling and a sinc-interpolating filter, this solution is specialized so it perfectly compensates for erasures. The second solution is an approximation to the general solution that computes the optimal, finite-length compensation for arbitrary LTI interpolation filters. The third is a finite-length windowed version of the oversampled, sinc-interpolating solution using discrete prolate spheroidal sequences. The last is an iterative algorithm in the class of projection onto convex sets. Analysis and results from numerical simulations are presented.
Faculty Opinions recommendation of Victorin, the host-selective cyclic peptide toxin from the oat pathogen Cochliobolus victoriae, is ribosomally encoded. (2020)

The necrotrophic fungal pathogen Cochliobolus victoriae produces victorin, a host-selective toxin (HST) essential for pathogenicity to certain oat cultivars with resistance against crown rust. Victorin is a mixture of highly modified heterodetic cyclic hexapeptides, previously assumed to be synthesized by a nonribosomal peptide synthetase. Herein, we demonstrate that victorin is a member of the ribosomally synthesized and posttranslationally modified peptide (RiPP) family of natural products. Analysis of a newly generated long-read assembly of the C. victoriae genome revealed three copies of precursor peptide genes (vicA1-3) with variable numbers of "GLKLAF" core peptide repeats corresponding to the victorin peptide backbone. vicA1-3 are located in repeat-rich gene-sparse regions of the genome and are loosely clustered with putative victorin biosynthetic genes, which are supported by the discovery of compact gene clusters harboring corresponding homologs in two distantly related plant-associated Sordariomycete fungi. Deletion of at least one copy of vicA resulted in strongly diminished victorin production. Deletion of a gene encoding a DUF3328 protein (VicYb) abolished the production altogether, supporting its predicted role in oxidative cyclization of the core peptide. In addition, we uncovered a copper amine oxidase (CAO) encoded by vicK, in which its deletion led to the accumulation of new glycine-containing victorin derivatives. The role of VicK in oxidative deamination of the N-terminal glycyl moiety of the hexapeptides to the active glyoxylate forms was confirmed in vitro. This study finally unraveled the genetic and molecular bases for biosynthesis of one of the first discovered HSTs and expanded our understanding of underexplored fungal RiPPs. PMID: 32929037
Silicon Heterojunction Interdigitated Back-Contact Solar Cells Bonded To Glass With Efficiency >21% (2017)

Previously, IMEC proposed the i2-module concept which allows to process silicon heterojunction interdigitated back-contact (SHJ-IBC) cells on thin ( &lt; 50 μm) Si wafers at module level. This concept includes the bonding of the thin wafer early on to the module cover glass, which delivers mechanical support to the wafer and thus significantly improves the production yield. In this work, we test silicone and ethylene vinyl acetate bonding agents and prove them to be resistant to all rear side processes, including wet and plasma processes. Moreover, a lift-off process using a sacrificial SiOx layer has been developed for emitter patterning to replace conventional lithography. The optimized process steps are demonstrated by the fabrication of SHJ-IBC cells on 6-inch 190 μm-thick wafers. Efficiencies up to 22.6% have been achieved on reference freestanding wafers. Excellent Voc of 734 mv and Jsc of 40.8 mA/cm2 lead to an efficiency of 21.7% on silicone-bonded cells, where the high Voc indicates the process compatibility of the bonding agent. The developments that enabled such achievements and the key factors that limit the device performance are discussed in this paper.
Apoptosis-inducing anti-HER2 agents operate through oligomerization-induced receptor immobilization (2021)

Overexpression of the receptor tyrosine kinase HER2 plays a critical role in the development of various tumors. Biparatopic designed ankyrin repeat proteins (bipDARPins) potently induce apoptosis in HER2-addicted breast cancer cell lines. Here, we have investigated how the spatiotemporal receptor organization at the cell surface is modulated by these agents and is distinguished from other molecules, which do not elicit apoptosis. Binding of conventional antibodies is accompanied by moderate reduction of receptor mobility, in agreement with HER2 being dimerized by the bivalent IgG. In contrast, the most potent apoptosis-inducing bipDARPins lead to a dramatic arrest of HER2. Dual-color single-molecule tracking revealed that the HER2 "lockdown" by these bipDARPins is caused by the formation of HER2-DARPin oligomer chains, which are trapped in nanoscopic membrane domains. Our findings establish that efficient neutralization of receptor tyrosine kinase signaling can be achieved through intermolecular bipDARPin crosslinking alone, resulting in inactivated, locked-down bipDARPin-HER2 complexes.
Safety assessment of new nanodiamonds@corrole hybrids addressed by the response of RAW-264.7 macrophages (2022)

Safety assessment of carbon nanomaterials is of paramount importance since they are on the frontline for applications in sensing, bioimaging and drug delivery. The biocompatibility and safety of functionalized nanodiamonds (NDs) are here addressed through the study of the pro-inflammatory response of RAW-264.7 macrophages exposed to new nanodiamonds@corrole hybrids. The corrole unit selected is as a prototype for a hydrophobic organic molecule that can function as a NIR fluorophore reporter, an optical sensor, a photodynamic therapy agent or a photocatalyst. The new functional nanohybrids containing detonated nanodiamonds (NDs) were obtained through esterification using carboxylated NDs and glycol corroles. The success of the covalent functionalization <i>via</i> carbodiimide activation was confirmed through X-ray photoelectron spectroscopy (XPS), Raman and Fourier transform infrared (FTIR) spectroscopy. The UV-vis absorption and emission spectra of the hybrids are additive with respect to the corrole features. The cellular uptake, localization, cell viability and effects on immune cell activation of the new hybrids and of the precursors were carefully investigated using RAW-264.7 macrophages. Overall results showed that the ND@corrole hybrids had no pro-inflammatory effects on the RAW-264.7 macrophage cell line, making them an ideal candidate for a wide range of biomedical applications.
Long Chain Omega-3 Fatty Acid Levels in Loin Muscle from Transgenic (fat-1 gene) Pigs and Effects on Lipid Oxidation During Storage (2011)

Abstract Studies suggest a diet rich in long chain omega-3 fatty acids (LCn3) can promote visual, neural and vascular health. Pork muscle typically has small amounts of LCn3. A transgenic technology involving the fat-1 gene has been developed to increase LCn3 in various pig tissues; however, pork loin muscle has not been examined to date. We have determined that the LCn3 content in loin muscle (Longissimus) from fat-1 pigs was 1.59–2.24 g/100 g lipid compared to 0.34–0.38 g/100 g lipid in control samples. Lipid oxidation products were measured in ground and salted loin muscle from control and fat-1 pigs during storage at −4°C. There was no clear trend as to whether the fat-1 gene technology increased or decreased oxidative stability of the muscle during storage based on lipid peroxide and thiobarbituric acid reactive substances (TBARS) values. There were a greater number of volatiles detected in stored loin from fat-1 pigs compared to control. Volatiles common to control and fat-1 pigs were elevated in stored loin from fat-1 pigs. This is the first report indicating that the use of fat-1 transgenic technology significantly increases the amount of desirable LCn3 in pork loin muscle. Keywords: transgenicporklipid profileomega-3 fatty acidsmeat qualityvolatilesswineView correction statement:Corrigendum ACKNOWLEDGMENTS This work was supported in part by the College of Agricultural and Life Sciences, University of Wisconsin-Madison, HATCH project WIS04904. We thank Melissa M. McDonald and Matthew L. Herkenhoff for assistance with analyses.
Logic of the Yeast Metabolic Cycle: Temporal Compartmentalization of Cellular Processes (2005)

Budding yeast grown under continuous, nutrient-limited conditions exhibit robust, highly periodic cycles in the form of respiratory bursts. Microarray studies reveal that over half of the yeast genome is expressed periodically during these metabolic cycles. Genes encoding proteins having a common function exhibit similar temporal expression patterns, and genes specifying functions associated with energy and metabolism tend to be expressed with exceptionally robust periodicity. Essential cellular and metabolic events occur in synchrony with the metabolic cycle, demonstrating that key processes in a simple eukaryotic cell are compartmentalized in time.
Shoe Midsole Longitudinal Bending Stiffness and Running Economy, Joint Energy, and EMG (2006)

Increasing midsole longitudinal bending stiffness led to improvements in running economy, yet the underlying mechanisms that can be attributed to this improvement are still not fully understood.
Multi-Target localization in asynchronous MIMO radars using sparse sensing (2017)

Multi-target localization, warranted in emerging applications like autonomous driving, requires targets to be perfectly detected in the distributed nodes with accurate range measurements. This implies that high range resolution is crucial in distributed localization in the considered scenario. This work proposes a new framework for multi-target localization, addressing the demand for the high range resolution in automotive applications without increasing the required bandwidth. In particular, it employs sparse stepped frequency waveform and infers the target ranges by exploiting sparsity in target scene. The range measurements are then sent to a fusion center where direction of arrival estimation is undertaken. Numerical results illustrate the impact of range resolution on multi-target localization and the performance improvement arising from the proposed algorithm in such scenarios.
Optical range plasmonics around the superconducting transition temperature of niobium metamaterial (2017)

By measuring the reflectivity of a nanostructured niobium film, we demonstrate a critical dependence of niobium’s optical response on its superconducting transition temperature around 9K. Our results suggest a hitherto unknown link between superconductivity and optical range plasmonics.
Reliability of myocardial perfusion quantification in angiography using a digital flat panel cardiac system (2002)

Discordance between lesion severity from angiocardiography and physiological effects has been reported elsewhere. Quantification of myocardial perfusion during the angiography procedure may supply additional information about short- and long-term outcomes and may be helpful for clinical decision making. In previous works, myocardial perfusion has been assessed using time density curves (TDC), which represent the contrast medium dilution over time in the myocardium. The mean transit time (MTT), derived from the TDC, has been reported as a good indicator of the regional myocardial perfusion. Our objective is to estimate the accuracy and reproducibility of MTT estimation on digital flat panel (DFP) images. We have simulated typical myocardium TDC obtained with a DFP cardiac system (Innova 2000, GE), taking into account scatter and noise. Logarithmic or linear subtractions have been applied to derive a contrast medium concentration proportional quantity from image intensity. A non-linear minimisation realises the model curve fitting. MTT estimates are more stable with linear subtraction in presence of scatter. However logarithmic subtraction presents smaller bias when scatter level is small. Both approaches are equally sensible to image noise. Linear subtraction should be preferred. Image noise has a high influence on MTT accuracy and we may reduce.
Self-Coherent Decision-Feedback-Directed 40-Gb/s DQPSK Receiver (2007)

A novel 40-Gb/s differential quadrature phase-shift keying receiver is theoretically proposed, improving direct detection by 4.2 dB for self-phase-modulation-limited single-channel transmission, approaching ideal coherent homodyne performance using a recirculating delay line interferometric integrated-optical circuit front-end combining decision feedback and nonlinear phase-noise compensation
The utility of contrast-enhanced endoscopic ultrasound in monitoring ethanol-induced pancreatic tissue ablation: a pilot study in a porcine model (2007)

EUS-guided alcohol injection consistently causes focal areas of pancreatic necrosis. Contrast-enhanced EUS with microspheres improves visualization of altered pancreatic vascular perfusion and can be used to facilitate detection of small pancreatic lesions and its follow-up post-ablation.
Effects of St. John's Wort Supplementation on Ibuprofen Pharmacokinetics (2007)

St. John's wort administration for 21 days had no apparent clinically important impact on the single-dose pharmacokinetic parameters of S(+)- and R(-)-ibuprofen. Although St. John's wort treatment appears to significantly reduce the mean residence time of S-ibuprofen, no ibuprofen dose adjustments appear warranted when the drug is administered orally with St. John's wort, due to the lack of significant change observed in ibuprofen AUC and C(max) for either enantiomer.
Small corpora and low-frequency phenomena: try and beyond contemporary, standard English (2018)

Small corpora remain an important resource for addressing questions requiring specialized data not found in large general purpose corpora. But do these small corpora have sufficient data to analyze low-frequency phenomena? This article presents a case study of the try-and-V pseudocoordination construction in English, which has an unusual morphosyntactic restriction: neither verb can be inflected. Diachronic corpora elucidate its origin as reanalysis from ambiguous usage of non-finite verbs in the late 1500s. Dialectal corpora reveal variation in frequency but not grammatical properties. And child language corpora reveal productive usage even by young children. These results are considered successful and the outlook is optimistic for addressing low-frequency phenomena beyond contemporary, standard English, especially as more, and more diverse, corpora become available.
Synthesis of Plakortone B and Analogues (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
1D Convolutional Neural Networks for Estimation of Compensatory Reserve from Blood Pressure Waveforms (2019)

We propose a Deep Convolutional Neural Network (CNN) architecture for computing a Compensatory Reserve Metric (CRM) for trauma victims suffering from hypovolemia (decreased circulating blood volume). The CRM is a single health indicator value that ranges from 100% for healthy individuals, down to 0% at hemodynamic decompensation - when the body can no longer compensate for blood loss. The CNN is trained on 20 second blood pressure waveform segments obtained from a finger-cuff monitor of 194 subjects. The model accurately predicts CRM when tested on data from 22 additional human subjects obtained from Lower Body Negative Pressure (LBNP) emulation of hemorrhage, attaining a mean squared error (MSE) of 0.0238 over the full range of values, including those from subjects with both low and high tolerance to central hypovolemia.
Characterization of a Nucleotide Kinase Encoded by Bacteriophage T7 (2012)

Gene 1.7 protein is the only known nucleotide kinase encoded by bacteriophage T7. The enzyme phosphorylates dTMP and dGMP to dTDP and dGDP, respectively, in the presence of a phosphate donor. The phosphate donors are dTTP, dGTP, and ribo-GTP as well as the thymidine and guanosine triphosphate analogs ddTTP, ddGTP, and dITP. The nucleotide kinase is found in solution as a 256-kDa complex consisting of ~12 monomers of the gene 1.7 protein. The two molecular weight forms co-purify as a complex, but each form has nearly identical kinase activity. Although gene 1.7 protein does not require a metal ion for its kinase activity, the presence of Mg(2+) in the reaction mixture results in either inhibition or stimulation of the rate of kinase reactions depending on the substrates used. Both the dTMP and dGMP kinase reactions are reversible. Neither dTDP nor dGDP is a phosphate acceptor of nucleoside triphosphate donors. Gene 1.7 protein exhibits two different equilibrium patterns toward deoxyguanosine and thymidine substrates. The K(m) of 4.4 × 10(-4) M obtained with dTTP for dTMP kinase is ~3-fold higher than that obtained with dGTP for dGMP kinase (1.3 × 10(-4) M), indicating that a higher concentration of dTTP is required to saturate the enzyme. Inhibition studies indicate a competitive relationship between dGDP and both dGTP, dGMP, whereas dTDP appears to have a mixed type of inhibition of dTMP kinase. Studies suggest two functions of dTTP, as a phosphate donor and a positive effector of the dTMP kinase reaction.
THEFERMIHAZE: A GAMMA-RAY COUNTERPART TO THE MICROWAVE HAZE (2010)

The Fermi Gamma-ray Space Telescope reveals a diffuse inverse Compton (IC) signal in the inner Galaxy with a similar spatial morphology to the microwave haze observed by WMAP, supporting the synchrotron interpretation of the microwave signal. Using spatial templates, we regress out π0 gammas, as well as IC and bremsstrahlung components associated with known soft-synchrotron counterparts. We find a significant gamma-ray excess toward the Galactic center with a spectrum that is significantly harder than other sky components and is most consistent with IC from a hard population of electrons. The morphology and spectrum are consistent with it being the IC counterpart to the electrons which generate the microwave haze seen at WMAP frequencies. In addition, the implied electron spectrum is hard; electrons accelerated in supernova shocks in the disk which then diffuse a few kpc to the haze region would have a softer spectrum. We describe the full-sky Fermi maps used in this analysis and make them available for download.
A 28nm poly/SiON CMOS technology for low-power SoC applications (2011)

This paper presents a state-of-the-art 28nm CMOS technology using conventional poly gate and SiON gate dielectric (Poly/SiON) with best-in-the-class transistor performance, SRAM SNM (static noise margin), MOM capacitance density and mismatch, and ULK (k=2.5) interconnect. The ION are 683 and 503 uA/um (at I OFF = 1nA/um, V DD =1V) for the n- and p-MOSFET, respectively. (With normalized t OX and V DD , these values are higher than prior publication by 5%/15%). The 6T-SRAM is aggressively scaled to &#60;0.124um2 with SNM of 193mV at 1.0V and 144mV at 0.7V. The via and metal resistances, and the metal-line RC time constants are competitive and well controlled. The characteristics for the RF passive components (MOM capacitor, varactor, and inductor) are also excellent.
Long-Term Prognostic Implications of Previous Silent Myocardial Infarction in Patients Presenting With Acute Myocardial Infarction (2018)

Silent MI occurred in 8.2% of patients presenting with first AMI and was independently related to poorer long-term clinical outcome, with a more than 3-fold risk of mortality and MACE. Silent MI holds prognostic value over important traditional prognosticators in the setting of AMI, indicating that these patients represent a high-risk subgroup warranting clinical awareness.
[DISRUPTIVE MOOD DYSREGULATION DISORDER - A NEW AND CHALLENGING DIAGNOSIS IN DSM-5]. (2018)

The year 2013 saw the publication of a new edition of the Diagnostic and Statistical Manual of Mental Disorders, the DSM-5. In this edition a new diagnosis - Disruptive Mood Dysregulation Disorder (DMDD) - was added. It defines children suffering from irritable and angry moods with frequent severe temper outbursts. The diagnosis is included in the chapter on mood disorders and relates only to children. This diagnosis was suggested in order to prevent over-diagnosis of bipolar disorder and over-use of antipsychotics and mood stabilizers in children. Studies indicate that DMDD constitutes a more significant risk factor for the development of unipolar disorder than for bipolar disorder. To date, no specific diagnostic tools have been developed for this diagnosis and there is relatively little treatment experience. Since this disorder has a wide range of comorbidities, the treatment focus tends to be on treating the comorbidities and includes medicines, cognitive-behavioral intervention and parental guidance.
Numerical implementation of magneto-acousto-electrical tomography (MAET) using a linear phased array transducer (2017)

In this study, the performance and implementation of magneto-acousto-electrical tomography (MAET) is investigated using a linear phased array (LPA) transducer. The goal of MAET is to image the conductivity distribution in biological bodies. It uses the interaction between ultrasound and a static magnetic field to generate velocity current density distribution inside the body. The resultant voltage due to velocity current density is sensed by surface electrodes attached on the body. In this study, the theory of MAET is reviewed. A 16-element LPA transducer with 1 MHz excitation frequency is used to provide beam directivity and steerability of acoustic waves. Different two-dimensional numerical models of breast and tumour are formed to analyze the multiphysics problem coupled with acoustics and electromagnetic fields. In these models, velocity current density distributions are obtained for pulse type ultrasound excitations. The static magnetic field is assumed as 1 T. To sense the resultant voltage caused by the velocity current density, it is assumed that two electrodes are attached on the surface of the body. The performance of MAET is shown through sensitivity matrix analysis. The sensitivity matrix is obtained for two transducer positions with 13 steering angles between [Formula: see text] to [Formula: see text] with [Formula: see text] angular intervals. For the reconstruction of the images, truncated singular value decomposition method is used with different signal-to-noise ratio (SNR) values (20 dB, 40 dB, 60 dB and 80 dB). The resultant images show that the perturbation (5 mm × 5 mm) placed 35 mm depth can be detected even if the SNR is 20 dB.