gebhart/patrepeval huggingface dataset:
A Framework for Visualizing Data Quality for Predictive Models and Clinical Quality Measures. (2019)

The ability to assess data quality is essential for secondary use of EHR data and an automated Healthcare Data Quality Framework (HDQF) can be used as a tool to support a healthcare organization's data quality initiatives. Use of a general purpose HDQF provides a method to assess and visualize data quality to quickly identify areas for improvement. The value of the approach is illustrated for two analytics use cases: 1) predictive models and 2) clinical quality measures. The results show that data quality issues can be efficiently identified and visualized. The automated HDQF is much less time consuming than a manual approach to data quality and the framework can be rerun repeatedly on additional datasets without much effort.
EGF induces increased ligand binding affinity and dimerization of soluble epidermal growth factor (EGF) receptor extracellular domain. (1991)

The binding of epidermal growth factor (EGF) to its cell surface receptor (EGF-R) results in a number of intracellular responses including the activation of the receptor intracellular tyrosine kinase. Receptor oligomerization induced by ligand binding has been suggested to play an important role in signal transduction. However, the mechanisms involved in oligomerization and signal transduction are poorly understood. We have produced and purified several milligrams of recombinant extracellular domain of the EGF receptor (EGF-Rx) using the baculovirus/insect cell expression system. The baculovirus-generated EGF-Rx is glycosylated, has had its signal peptide correctly cleaved, and exhibits a dissociation constant for EGF similar to that for solubilized full-length receptor, of about 100 nM. The binding of EGF to EGF-Rx leads to the formation of receptor dimers and higher oligomerization states which are irreversibly captured using the covalent cross-linking agent disuccinimidyl suberate. Interestingly, purified receptor monomers and dimers, stabilized by the cross-linker in the presence of EGF, exhibit increased binding affinity toward EGF as compared with receptor monomers which have not been exposed to EGF. It appears that the high affinity state of receptor can be maintained by the covalent cross-linking agent. These results indicate that in addition to ligand binding, the extracellular domain of EGF receptor possesses the inherent ability to undergo ligand-induced dimerization and that the low affinity state is converted to a high affinity state by EGF.
A Model-Independent Measure of Regression Difficulty (2000)

data mining, machine learning, model fitting, regression, exploratory data analysis, error rate estimation, data modeling, data cleaning, data preparation, predictability We prove an inequality bound for the variance of the error of a regression function plus its non-smoothness as quantified by the Uniform Lipschitz condition. The coefficients in the inequality are calculated based on training data with no assumptions about how the regression function is learned. This inequality, called the Unpredictability Inequality, allows us to evaluate the difficulty of the regression problem for a given dataset, before applying any regression method. The Inequality gives information on the tradeoff between prediction error and how sensitive predictions must be to predictor values. The Unpredictability Inequality can be applied to any convex subregion of the space X of predictors. We improve the effectiveness of the Inequality by partitioning X into multiple convex subregions via clustering, and then applying the Inequality on each subregion. Experimental results on genuine data from a manufacturing line show that, combined with clustering, the Unpredictability Inequality provides considerable insight and help in selecting a regression method. Internal Accession Date Only © Copyright
A Novel Quad-Band Branched Monopole Antenna with a Filter Suppressing Higher Order Modes (2023)

This paper proposes a novel quad-band branched monopole antenna with a filter. The proposed antenna has a simple configuration in which branch-elements are added to a basic configuration consisting of a mast and dielectric wires. The antenna is characterized by performances such as wideband impedance matching, gain stabilization, and gain enhancement. Wideband impedance characteristics satisfying the voltage standing ratio of less than 2 are obtained by exciting a parallel resonance at the lowest band and multi-resonance at high bands. The filter suppressing higher order modes is used for gain stabilization, so that averaged gains above 5dBi are obtained at the quad-band. The antenna has a high gain of 11.1dBi because the branch-elements work as an end-fire array antenna at the highest band. Furthermore, it is clarified that an operating frequency is switched by using a variable bandpass filter at the lowest band. Last, a scale model of the antenna is fabricated and measured, then the effectiveness of the proposed antenna is demonstrated.
A Powered Leg Orthosis for Gait Rehabilitation of Motor-Impaired Patients (2007)

This paper describes a powered leg orthosis for gait rehabilitation of patients with walking disabilities. The paper proposes controllers which can apply suitable forces on the leg so that it moves on a desired trajectory. The description of the controllers, simulations and experimental results with the powered orthosis are presented in the paper. Currently, experiments have been performed with a dummy leg in the orthosis. In the coming months, this powered orthosis will be used on healthy subjects and stroke patients.
Prolactine et hormone ovulatoire du cobaye (1977)

Prolactin and luteinizing hormone secretion control in guinea pig. Ovine prolactin infused intraventricularly to male guinea-pig induces changes in the hypothalamic LH-RH neurons counted by immunofluorescence. This action is rapid and lasting and is accompanied by an increase in plasma LH which is radioimmunoassayed. Prolactin appears to stimulate LH-RH synthesis and release. The possibility of direct hypothalamic prolactin action interfering with LH-RH neurons by way of the aminergic system is discussed.
Prototyping parallel and distributed programs in Proteus (2002)

This paper presents Proteus, an architecture-independent language suitable for prototyping parallel and distributed programs. Proteus is a high-level imperative notation based on sets and sequences with a single construct for the parallel composition of processes. Although a shared-memory model is the basis for communication between processes, this memory can be partitioned into shared and private variables. Parallel processes operate on individual copies of private variables, which are independently updated and may be merged into the shared state at specifiable barrier synchronization points. Several examples are given to illustrate how the various parallel programming models, such as synchronous data-parallelism and asynchronous control-parallelism, can be expressed in terms of this foundation. This common foundation allows prototypes to be tested, evolved and finally implemented through refinement techniques targeting specific architectures.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Preclinical evaluation of group B Neisseria meningitidis and Escherichia coli K92 capsular polysaccharide-protein conjugate vaccines in juvenile rhesus monkeys (1997)

We reported the first use of group B meningococcal conjugate vaccines in a nonhuman primate model (S. J. N. Devi, C. E. Frasch, W. Zollinger, and P. J. Snoy, p. 427-429, in J. S. Evans, S. E. Yost, M. C. J. Maiden, and I. M. Feavers, ed., Proceedings of the Ninth International Pathogenic Neisseria Conference, 1994). Three different group B Neisseria meningitidis capsular polysaccharide (B PS)-protein conjugate vaccines and an Escherichia coli K92 capsular polysaccharide-tetanus toxoid (K92-TT) conjugate vaccine are here evaluated for safety and relative immunogenicities in juvenile rhesus monkeys with or without adjuvants. Monkeys were immunized intramuscularly with either B PS-cross-reactive material 197 conjugate, B PS-outer membrane vesicle (B-OMV) conjugate, or N-propionylated B PS-outer membrane protein 3 (N-pr. B-OMP3) conjugate vaccine with or without adjuvants at weeks 0, 6, and 14. A control group of monkeys received one injection of the purified B PS alone, and another group received three injections of B PS noncovalently complexed with OMV. Antibody responses as measured by enzyme-linked immunosorbent assay varied among individual monkeys. All vaccines except B PS and the K92-TT conjugate elicited a twofold or greater increase in total B PS antibodies after one immunization. All vaccines, including the K92-TT conjugate, elicited a rise in geometric mean B PS antibody levels of ninefold or more over the preimmune levels following the third immunization. Antibodies elicited by N-pr. B-OMP3 and B-OMV conjugates were directed to the N-propionylated or to the spacer-containing B PS antigens as well as to the native B PS complexed with methylated human serum albumin. None of the vaccines caused discernible safety-related symptoms.
Development of Vapor Reducing Fuel Tank System (2001)

&lt;div class="htmlview paragraph"&gt;In succession to the world-first introduction of a mass production gasoline hybrid passenger car into the Japanese market in 1997, Toyota also has introduced an enhanced version of the above to the US and European markets in 2000.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;Upon introduction of Toyota Hybrid System (THS) into the US market, a drastic reduction of gasoline vapor evaporation from the fuel tank was necessary, in order to meet the most stringent exhaust emission (SULEV) and evaporative emission standards in the world.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;In order to meet this requirement, a fuel tank system named “Vapor Reducing Fuel Tank System” was developed. This is the first commercial application in the world to use a variable tank volume to drastically reduce gasoline vapor generation.&lt;/div&gt;
Same-Day Mode Choice Modeling with Household Vehicle Usage Simulation in Developing Countries (2011)

This paper presents a model of same-day mode choice at the household level for developing countries. A rule-based algorithm combining classical random utility maximization theory within a microsimulation framework is used. Modeling of private vehicle usage (including vehicle allocation and sharing use in household) is an essential component of this model because vehicle deficiency is common in developing countries. This model consists of four steps: (a) the allocation of private vehicles (car, motorcycle, and bicycle) in a household, (b) the mode choice of private vehicle users specified in the first step, (c) vehicle sharing in a household, and (d) the mode choice of individuals who do not use private vehicles. The adaptability of the model was improved by simulations on car, motorcycle, and bicycle usage. Discrepancies in the mode choice behavior of household members with and without the use of private vehicles are captured in this paper through different modeling methods. The rule-based algorithm, binary logit model, multinomial logit model, and mixed logit model were applied together in this four-step model. Travel diary survey data from 2007 from Bengbu, China, were used as an example for the validation test of this model. The results demonstrate that this model can accurately predict the mode choice of all household members in an internally self-consistent and theoretically credible manner for a midsize city in China. The proposed model is highly conducive to travel demand forecasting and transportation policy making.
Novel device to conduct flash-heat treatment in efforts to reduce mother-to-child HIV transmission in low-resource areas (2012)

The objective of this design project was to create a device to prevent mother-to-child transmission (MTCT) of HIV through breast milk in preterm infants. Our team created a robust and intuitive device which utilizes Flash Heat Treatment (FHT), an established method to inactivate HIV. The FHT method heats jarred breast milk in boiling water for a short amount of time, enough to denature HIV reverse transcriptase while preserving the nutritional value of breast milk. Thorough observation of users and available resources in Cape Town, South Africa enabled establishment of a design that can be used in urban/peri-urban areas. User research conveyed that low cost and effortless household adaptability were the most important elements of the design. As a result, a modified electric kettle was designed to function as a breast milk pasteurization device. Published data illustrating temperature curves during FHT with corresponding virology tests on the pasteurized milk were used to verify whether the device is likely to function effectively. Experimental results indicate that the device matches the required temperature profile. After virology experimentation is complete, the new device may be incorporated into hospitals as well as households in the Cape Town area, and may be expanded to other low resource periurban/urban areas as well.
Nature of N-Bromosuccinimide in Basic Media: The True Oxidizing Species in the Hofmann Rearrangement (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNature of N-Bromosuccinimide in Basic Media: The True Oxidizing Species in the Hofmann RearrangementChris H. Senanayake, Laura E. Fredenburgh, Robert A. Reamer, Robert D. Larsen, Thomas R. Verhoeven, and Paul J. ReiderCite this: J. Am. Chem. Soc. 1994, 116, 17, 7947–7948Publication Date (Print):August 1, 1994Publication History Published online1 May 2002Published inissue 1 August 1994https://pubs.acs.org/doi/10.1021/ja00096a082https://doi.org/10.1021/ja00096a082research-articleACS PublicationsRequest reuse permissionsArticle Views1182Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Field emission testing of carbon nanotubes for THz frequency vacuum microtube sources (2004)

A carbon nanotube-based high current density electron field emission source is under development at Jet Propulsion Laboratory (JPL) for submillimeter-wave power generation (300 GHz to 3 THz). This source is the basis for a novel vacuum microtube component: the <i>nanoklystron</i>. The nanoklystron is a monolithically fabricated reflex klystron with dimensions in the micrometer range. The goal is to operate this device at much lower voltages than would be required with hot-electron sources and at much higher frequencies than have ever been demonstrated. Both single-walled (SWNTs) as well as multi-walled nanotubes (MWNTs) are being tested as potential field-emission sources. This paper presents initial results and observations of these field emission tests. SWNTs and MWNTs were fabricated using standard CVD techniques. The tube density was higher in the case of MWNT samples. As previously reported, high-density samples suffered from enhanced screening effect thus decreasing their total electron emission. The highest emission currents were measured from disordered, less dense MWNTs and were found to be ~0.63 mA @ 3.6 V/&mu;m (sample 1) and ~3.55 mA @ 6.25 V/&mu;m (sample 2). The high density vertically aligned MWNTs showed low field emission as predicted: 0.31 mA @ 4.7 V/&mu;m.
Magnetic and uniaxial stress perturbations of optical transitions at a four Li atom complex in Si (1984)

Zeeman measurements are reported on the 1044 and 1045 meV lines of a Li centre in Si, showing that the lower-energy line involves a spin triplet excited state and the higher-energy line a spin singlet excited state. Uniaxial stress data are analysed to show that the transitions occur at a trigonal centre and have orbital Gamma 3 excited states with properties very similar to the valence band and conduction band extrema of Si.
Implementation of a W-CDMA Direct-Conversion IQ Modulator Module Including Evaluation of Chip-Package-Board Interactions (2006)

This paper presents a W-CDMA direct-conversion IQ modulator MMIC design that employs a new technique to generate the 90deg phase shift with low implementation loss. The package and PCB effects on the implemented IQ modulator MMIC when further developed as a board module are studied. The package and PCB interconnects are analyzed using the 3-D EM simulation tool and transformed into the equivalent-circuit elements for co-simulation with the IQ modulator MMIC. The degradation of error vector magnitude and sideband suppression due to the presence of package and PCB can be well predicted by the co-simulation results and then verified by the final measurement results
The synthetic antimicrobial peptide LTX21 induces inflammatory responses in a human whole blood model and a murine peritoneum model (2019)

The global spread of antimicrobial resistance and the increasing number of immune-compromised patients are major challenges in modern medicine. Targeting bacterial virulence or the human host immune system to increase host defence are important strategies in the search for novel antimicrobial drugs. We investigated the inflammatory response of the synthetic short antimicrobial peptide LTX21 in two model systems: a human whole blood ex vivo model and a murine in vivo peritoneum model - both reflecting early innate immune response. In the whole blood model, LTX21 increased the secretion of a range of different cytokines, decreased the level of tumour necrosis factor (TNF) and activated the complement system. In a haemolysis assay, we found 2.5% haemolysis at a LTX21 concentration of 500 mg/L. In the murine model, increased influx of white blood cells (WBCs) and polymorphonuclear neutrophils (PMNs) in the murine peritoneal cavity was observed after treatment with LTX21. In addition, LTX21 increased monocyte chemoattractant protein-1 (MCP-1). In conclusion, LTX21 affected the inflammatory response; the increase in cytokine secretion, complement activation and WBC influx indicates an activated inflammatory response. The present results indicate the impact of LTX21 on the host-pathogen interplay. Whether this will also affect the course of infection has to be investigated.
A low-power Cu atom switch programmable logic fabricated in a 40nm-node CMOS technology (2017)

For the first time, a 40nm-node, 2× logic density, 3.8× operation speed, and 3× power efficient, nonvolatile programmable logic (NPL) is demonstrated by using Cu atom switch for configuration switches. The switching characteristics of the atom switch are kept in scaling down to 64/32nm device area, and an improved PSE reduces set voltage while keeping low leakage current, enabling core transistors to select the atom switches. The developed 40nm NPL is a strong candidate for the next wave of energy-efficient computing.
Neurotoxic Disorders (2003)

The nervous system is commonly impacted by chemicals found in nature, elaborated by organisms, or synthesized by chemists. The peculiar architecture of neural cells, their high-energy demands, and the mandate for electrochemical communication combine to place the nervous system at high risk for chemical perturbation. This inherent vulnerability is exploited by natural agents, synthetic chemicals, medications, and recreational substances designed or used to target the nervous system as well as by a host of other substances that are occasionally encountered in the environment. The neurotoxic actions of chemicals are expressed in a wide range of neurologic phenomena, some of which are associated with purely functional changes, others with structural damage, and still others with both. Many chemicals cause effects that appear and disappear rapidly; others produce effects that evolve over days or weeks and regress over months or years. Diagnosis is heavily dependent on the history and characteristic clinical phenomenology. Specific treatment other than termination of exposure is rare. Although clinical improvement is the rule, neurotoxic disorders leave scars or disappear without a trace.
Genomics and Post-Genomics Research in the European Research Area (2001)

The European Research Area (ERA) provides a unique framework for organizing and structuring agricultural genomics and post-genomics research in Europe. The principal features of this novel trend in biological research are high technological sophistication and multidisciplinarity. The successful development of this research activity requires a high degree of focus as regards the research effort and international cooperation and coordination, which can only be achieved by combining national competencies through the development of high-throughput facilities and laboratories, bioinformatics infrastructure and a network of centres of excellence throughout Europe.
Filter Design Considerations for Acquisition of BOC-modulated Galileo Signals (2006)

In this paper we study the effect of the transition band in designing both FIR- and IIR-types of digital filters, as possible bandwidth-limiting receiver filters, during the CDMA code acquisition of a BOC-modulated and over-sampled Galileo signal. It is shown that using an asymmetric transition band (i.e., the band between the passband and stopband frequencies) with respect to one fourth of the sampling rate, the performance, in terms of root mean square errors (RMSE), can be improved for both FIR and IIR filters compared to the situation with symmetric transition bands. As an optimum bound we have employed the ideal rectangular pulse (i.e. no bandwidth limitation). All investigated filtering methods still suffer from some performance degradation, compared to rectangular shaping. The analysis is done here for both static and fading multipath channels
ChemInform Abstract: On the Preparation of Optically Active Secondary Alcohols from a 1,3‐Dioxan‐4‐one: Substitution with Organocopper Reagents. (1986)

Abstract Aus dem Silylester‐Derivat (I) erhält man mit Heptanal (II) das Dioxanon (III), das durch die Organo‐Lithiumverbindungen (IV) selektiv zu den cis‐Verbindungen (V) geöffnet wird.
Temperature Dependence of the Ultraviolet Absorption Edges in SnO2 (1966)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Robert Summitt, N. F. Borrelli; Temperature Dependence of the Ultraviolet Absorption Edges in SnO2. Journal of Applied Physics 1 April 1966; 37 (5): 2200. https://doi.org/10.1063/1.1708779 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioJournal of Applied Physics Search Advanced Search |Citation Search