gebhart/patrepeval huggingface dataset:
[Corrigendum] Recent advances in the molecular mechanisms of Mayer‑Rokitansky‑Kï¿½ster‑Hauser syndrome (Review) (2017)

Subsequent to the publication of this article, some interested readers advised the authors that a sentence in the manuscript may be misunderstood. Therefore, the authors have amended the sentence, ‘The uterus was exchanged between two cynomolgus monkeys and one successfully achieved natural pregnancy following menstruation (36)’, page 125, right column, line 7, to, ‘In uterine autotransplantation in cynomolgus macaques, one successfully achieved natural pregnancy following menstruation (36)’. The authors guarantee that this modification does not alter the conclusions discussed in the review, and apologize for any misunderstanding caused. [the original article was published in the Biomedical Reports 7: 123-127, 2017; DOI: 10.3892/br.2017.929]
Flexible district heating network model that predicts mass flow, pressure and temperature losses (2019)

Buildings play an important role in urban energy systems. It is no longer enough to simulate building energy use isolated from the supply energy source. Therefore, simulation and optimisation of a district heating networks needs of efficient, fast and realistic models of the individual network elements in order to correctly predict heat losses, temperature propagation, pressure drops and mass flow rates. In addition, the urbanization of new areas beyond the existing ones implies the expansion of the district heating network, demanding the new models to be flexible to adapt to the topology changes. This project presents the mathematical derivation and software implementation in Matlab of a thermo-hydraulic model based in the ‘Element Method’ in which the topology is implemented as an input, and temperature, pressure and mass flow are calculated according to the consumption from the nodes. It is a general tool that could be used as a framework due to its flexibility and adaptability. Currently the presented variables above are calculated for a linear network topology. However, future developments will allow to implement a matrix for more advanced topologies like a tree network. In addition, validation of the temperature loss along the pipes with experimental measurements during steady state conditions have shown a deviation of less than 5%.
Understanding Meaningful Participation and the Situated Use of Technology in Community Music for Active Ageing (2020)

Abstract An unfortunate tendency in previous HCI research has been to give the impression that it aims to ‘fix the problem’ of human ageing, suggesting a ‘deficit’ model of ageing or a ‘prosthetic’ model of technology. We conducted diary-aided interviews to investigate how technology use is situated in active, healthy older adults’ meaningful participation in community music. We argue that recognizing community music practices and technology use as situated action provides opportunities to grasp the subtleties of social participation and design for active ageing. We identified technology-mediated music practices, such as music sharing and revisiting, and how they evolved through the reconfiguration of connections between technology, competence, and forward-facing identities. We found that identity development, via routes such as exercising control, role transitions, and social spaces, had psychological significance and implications for active ageing. We explore how HCI leverages the perspective of active ageing and might facilitate older adults’ meaningful participation enhanced by technologies.
Ion Species Fractions in the Far-Field Plume of a High-Specific Impulse Hall Thruster (2003)

An ExB probe was used to measure the ion species fractions of Xe(+), Xe(2+), and Xe(3+) in the far-field plume of the NASA-173Mv2 laboratory-model Hall thruster. The thruster was operated at a constant xenon flow rate of 10 milligrams per second and discharge voltages of 300 to 900 V. The ExB probe was placed two meters downstream of the thruster exit plane on the thruster centerline. At a discharge voltage of 300 V, the species fractions of Xe(2+) and Xe(3+) were lower, but still consistent with, previous Hall thruster studies using other mass analyzers. Over discharge voltages of 300 to 900 V, the Xe(2+) species fractions increased from 0.04 to 0.12 and the Xe(3+) species fraction increased from 0.01 to 0.02.
ACTH-Independent Cushing’s Syndrome: Primary Pigmented Nodular Adrenal Disease in the Context of Carney’s Complex (2010)

In this chapter, we discuss clinical and molecular findings of micronodular adrenal hyperplasias (MAHs) that lead to ACTH-independent Cushing syndrome. We focus on the role of genetic defects in cyclic AMP (cAMP) signaling-related molecules, namely PRKAR1A, GNAS, PDE11A, and PDE8B; molecular defects in the phosphodiesterases (PDE) family are the most recently discovered genetic defects predisposing to adrenocortical tumor formation. The prototype of these disorders was Carney complex (CNC) in the context of which the first MAH was described: primary pigmented nodular adrenocortical disease or PPNAD. PPNAD is due to defects in PRKAR1A, the gene that functions as a receptor for the cAMP. In contrast to GNAS and PRKAR1A, defects in PDE genes are associated more frequently with incomplete penetrance. Identifying low-penetrance mutations in more than one PDE in patients with MAHs is suggestive for a complementary role of the different PDEs in the adrenal gland, and possible involvement of other members of this gene family in adrenocortical tumors and ACTH-independent Cushing syndrome.
Call admission control using the moving pattern of mobile user for mobile multimedia networks (2003)

In this paper, a call admission control mechanism is proposed to provide a consistent QoS guarantee for multimedia traffic on a mobile computing environment. Each cell can reserve fractional bandwidth for handoff calls to its adjacent cells. It is important to determine the right amount of bandwidth reserved for handoff calls because the blocking probability of new calls may increase if the amount of reserved bandwidth is more than necessary. An adaptive bandwidth reservation based on a mobility graph and a 2-tier cell structure is proposed to determine the amount of bandwidth to be reserved in the cell and to control dynamically its amount according to network conditions. We also propose a call admission control based on this bandwidth reservation and "next-cell prediction" scheme using a mobility graph. In order to evaluate the performance of our call admission control mechanism, we measure metrics such as blocking probability of new calls, dropping probability of handoff calls, and bandwidth utilization. The simulation results show that the performance of our mechanism is superior to that of existing mechanisms such as NR-CAT2, FR-CAT2, and AR-CAT2.
All-Directional Dual Pixel Auto Focus Technology in CMOS Image Sensors (2021)

We developed a dual pixel with accurate and all-directional auto focus (AF) performance in CMOS image sensor (CIS). The optimized in-pixel deep trench isolation (DTI) provided accurate AF data and good image quality in the entire image area and over whole visible wavelength range. Furthermore, the horizontal-vertical (HV) dual pixel with the slanted in-pixel DTI enabled the acquisition of all-directional AF information by the conventional dual pixel readout method. These technologies were demonstrated in 1.4μm dual pixel and will be applied to the further shrunken pixels.
Shake Table Testing of Shear-Controlling Rocking Isolation Podium System for Mitigating Higher-Mode Effects in Tall Buildings (2023)

This paper presents shake table testing results of a scaled tower specimen equipped with a novel self-centering shear and moment dual-base mechanism system, termed the shear-controlling rocking isolation podium (SCRIP) system, for mitigating higher-mode effects in tall buildings. The scaled shake table specimen of the SCRIP system consists of a shear mechanism that controls base shear demands through the lateral response of a base podium supported by rocking columns below and friction braces in the periphery, in addition to a free-rocking mechanism above the base podium to limit the base overturning moment demands of the tower. Both mechanisms are designed to exhibit full self-centering capabilities. There were 220 shake table tests performed using two suites of ground motion (GM) excitations with increasing amplitudes from 50% to 150% in increments of 25%. The scaled SCRIP system was shown to reliably control both the peak base shear and overturning moment demands close to the design values even as the excitation amplitudes were increased. Seismic demands along the height of the tower above the SCRIP system were also well controlled. Negligible changes in the lateral resistance of the scaled SCRIP system were observed throughout the shaking table test program with no apparent damage or measured residual deformations. The bidirectional capability of the scaled SCRIP system was also experimentally demonstrated through GM excitations applied diagonally with respect to the system’s two principal horizontal directions. In addition, these results experimentally verified the concept of limiting both shear and overturning moment at the base of a slender structure to control the seismic demands and associated higher-mode effects along the height of the structure.
Comment réduire l’impact environnemental de la microélectronique dans un domaine du semi-conducteur en pleine évolution ? (2023)

La microélectronique fait désormais partie intégrante des stratégies de nombreux pays, et l’on peut gager que le paysage mondial se recomposera dans les prochaines années pour rééquilibrer la chaîne de valeur. C’est dans ce contexte inédit que la question de l’impact environnemental de la microélectronique se pose de façon croissante à travers la production de ses composants, mais aussi à travers ses usages. Les acteurs de l’industrie et de la recherche se mobilisent pleinement pour concrétiser, au travers d’actions concrètes, l’objectif de réduction de son empreinte carbone. Ils intègrent également cette dimension dans la conception des futurs technologies et composants de la microélectronique. Dans cet article, nous dressons un état des lieux des enjeux et initiatives en la matière et donnons des exemples concrets des innovations en cours, notamment au CEA.
Input Imaging Media And Their Theoretical Colour Gamuts (2002)

The colour gamuts of colour reproduction media are important properties of them and can play a decisive role in their use in colour reproduction applications as well as the improvement of their capabilities. While this topic has frequently been studied and is well understood and for output colour imaging media, a solution for input media is not to be had in a simple way. To this end, the present paper proposes a method for obtaining the theoretical gamut across which a device can capture colour differences and this method is based on simulating the responses of an input medium to given spectral power distributions. The gamut of an input medium is then determined on the basis of having a set of spectra that cover the majority of all possible spectra, knowing a medium's responses to them and then determining a boundary beyond which the medium does not produce variation in its responses. The present paper is an abridged version of a more extensive treatment of the topic submitted for journal publication.
Effects of Ce-based additions during texturing of YBa2Cu3O7−δ (1997)

The effects of CeO2 and BaCeO3 additions on the microstructure of melt textured YBa2Cu3O7−δ and the extent of interactions between Ce-based additions and the peritectic melt have been investigated. Both types of additions are effective in reducing the coarsening of Y2BaCuO5 particles in the melt during texturing. This appears to be due, in part, to some Ce solubility in the melt which is thought to modify the 211/liquid phase interfacial energy.
Backscattering amplitude in ultrasound localization microscopy (2023)

In the last decade, Ultrafast ultrasound localisation microscopy has taken non-invasive deep vascular imaging down to the microscopic level. By imaging diluted suspensions of circulating microbubbles in the blood stream at kHz frame rate and localizing the center of their individual point spread function with a sub-resolution precision, it enabled to break the unvanquished trade-off between depth of imaging and resolution by microscopically mapping the microbubbles flux and velocities deep into tissue. However, ULM also suffers limitations. Many small vessels are not visible in the ULM images due to the noise level in areas dimly explored by the microbubbles. Moreover, as the vast majority of studies are performed using 2D imaging, quantification is limited to in-plane velocity or flux measurements which hinders the accurate velocity determination and quantification. Here we show that the backscattering amplitude of each individual microbubble can also be exploited to produce backscattering images of the vascularization with a higher sensitivity compared to conventional ULM images. By providing valuable information about the relative distance of the microbubble to the 2D imaging plane in the out-of-plane direction, backscattering ULM images introduces a physically relevant 3D rendering perception in the vascular maps. It also retrieves the missing information about the out-of-plane motion of microbubbles and provides a way to improve 3D flow and velocity quantification using 2D ULM. These results pave the way to improved visualization and quantification for 2D and 3D ULM.
The Sociology of Health, Healing, and Illness (2023)

With thorough coverage of inequality in health care access and practice, this leading textbook is widely acclaimed by instructors as the most comprehensive of any available. Written in an engaging and accessible style, with multiple student-friendly features, it integrates recent research in medical sociology and public health to introduce students to a wide range of issues affecting health, healing, and health care today. This new edition links information on COVID-19 into each chapter, providing students with a solid understanding of the social history of medicine; social epidemiology; social stress; health and illness behavior; the profession of medicine; nurses and allied health workers; complementary and alternative medicine; the physician-patient relationship; medical ethics; and the financing and organization of medical care. Important changes and enhancements in the eleventh edition include: Inclusion of material on COVID-19 in the main text of every chapter, with special sections at the end of each chapter exploring additional intersections of COVID-19 with chapter content. Expanded coverage of fundamental cause theory and the social determinants of health. New centralized discussions of how and why social disparities in race, class, gender, and sexual identity impact health outcomes in the United States. New “In the Field” boxed inserts on topics such as medical education and student debt, physicians’ use of medical jargon, and corporate greed. New “In Comparative Focus” boxed inserts on topics such as the 1918 influenza pandemic, infant and maternal mortality in Afghanistan, the patient care coordination process, drug prices, long-term care, and global health. A more in-depth look at both physician and nursing shortages. Expanded discussion of nurse burnout during the COVID-19 pandemic. Curricular and pedagogical changes in medical schools. Discussion of continued changes in the financing of the US health care system. A more in-depth look at quality concerns in nursing homes. Increased attention to the health care systems in Norway, Germany, Cuba, and Mexico. An updated instructor’s guide with test bank and PowerPoint slides.
Design and fabrication of a coupled microneedle array and insertion guide array for safe penetration through skin (2004)

Ordinary flat hollow tip, microneedles have been designed and fabricated for biomedical MEMS applications. With the facilitation of an insertion guide, the needles can be pushed down through the viable-epidermis with less bending. The microneedle array has the ability of integration with microfluidic devices since the needles are hollow so that the liquid can flow through the holes. 100 microneedles are contained in a 5 /spl times/ 5 mm/sup 2/ array chip and the same size of another array chip contains 100 insertion guide holes. A standard silicon micromachining process was employed to fabricate both arrays. The shape of microneedle is as simple as a tube so that the designed theories and simulations can be more precise than the complicated shape. The result of testing shows that there was no microneedle broken during the penetration to the skin via the guiding holes. The finite-element analyses of stresses and deformed shapes have been carried out with the explanation of deformed shape and stress occurred in the needle structure.
Formulation of Gelled Non-toxic Bicontinuous Microemulsions Stabilized by Highly Efficient Alkanoyl Methylglucamides (2020)

Gelled non-toxic bicontinuous microemulsions have a great potential for transdermal drug delivery as the microemulsion facilitates the solubilization of both hydrophilic and hydrophobic drugs, while the gel network provides mechanical stability and thus an easy application on the skin. In our previous study, we formulated a gelled non-toxic bicontinuous microemulsion: we gelled the system H<sub>2</sub>O-isopropyl myristate (IPM)-Plantacare 1200 UP (C<sub>12</sub>G<sub>1.4</sub>)-1,2-octanediol with the low molecular weight organogelator 1,3:2,4-dibenzylidene-d-sorbitol (DBS). However, a large amount of Plantacare 1200 UP (12 wt %) is needed to form a bicontinuous microemulsion. To solve this problem, we studied a new class of surfactants, namely, alkanoyl methylglucamides (MEGA), which have been rarely used for the formulation of microemulsions. The phase behavior of microemulsions stabilized by MEGA-8/10, MEGA-12/14-PC, and MEGA-12/14-HC was compared with that of systems stabilized by alkyl polyglucosides. We found that even with 2 wt % MEGA-12/14-HC, a bicontinuous microemulsion can be formed, which is 1/6 of the amount of Plantacare 1200 UP. The bicontinuous microstructure of the non-toxic microemulsion H<sub>2</sub>O-IPM-MEGA-12/14-HC-1,2-octanediol was confirmed by small-angle neutron scattering. Furthermore, the phase boundaries remained unchanged when gelled by DBS. The rheological properties of the gel were studied by oscillatory shear rheometry. Finally, freeze-fracture electron microscopy images show the coexistence of gel fibers and bicontinuous oil and water domains. These results suggest that the new gelled non-toxic bicontinuous microemulsion is an orthogonal self-assembled system.
The Effects of H2S and Recombinant Human Hsp70 on Inflammation Induced by SARS and Other Agents In Vitro and In Vivo (2022)

The ongoing epidemic caused by SARS-CoV-2 infection led to the search for fundamentally new ways and means to combat inflammation and other pathologies caused by this virus. Using a cellular model of lipopolysaccharide (LPS)-induced sepsis (human promonocytes), we showed that both a hydrogen sulfide donor (sodium thiosulfate, STS) and a recombinant Heat shock protein 70 (rHsp70) effectively block all major inflammatory mediators when administrated before and after LPS challenge. The protective anti-inflammatory effect of rHsp70 and H<sub>2</sub>S was also confirmed in vivo using various animal models of pneumonia. Specifically, it was found that rHsp70 injections prevented the development of the acute respiratory distress syndrome in highly pathogenic pneumonia in mice, increased animal survival, and reduced the number of Programmed death-1 (PD-1)-positive T-lymphocytes in peripheral blood. Based on our model experiments we developed a combined two-phase therapeutic approach for the treatment of COVID-19 patients. This procedure includes the inhalation of hot helium-oxygen mixtures for induction of endogenous Hsp70 in the first phase and STS inhalation in the second phase. The use of this approach has yielded positive results in COVID-19 patients, reducing the area of lung lesions, restoring parameters of innate immunity and T-cell immune response against coronavirus infection, and preventing the development of pulmonary fibrosis and immune exhaustion syndrome.
Losses of ions during forward and reverse scans in a quadrupole ion trap mass spectrometer and how to reduce them (1997)

The higher order fields present in the quadrupole ion trap may have beneficial effects such as increases in mass resolution in the mass-selective instability or resonance ejection modes of operation, but may also result in losses of ions due to nonlinear resonances. In this work, the reduction in ion intensities observed in the mass spectra of polyethylene glycol (PEG 1000) has been utilized to monitor the ion losses resulting from these higher order fields during the rf voltage scans in both the forward and reverse directions. Extensive ion losses were observed in reverse rf voltage scans at qz=0.64 (az=0), which corresponds to octopole resonance at βz=1/2. The losses depended upon rf voltage scan rate and ion mass being greater for lower scan rates and lower masses. For ions of m/z 877, losses of up to 60% of the stored ions were observed at low scan rates (<1×104 Da/s), but were minimal at higher scan rates. Thus, it is possible to avoid such losses during reverse scans by scanning the region qz=0.64 at rates in excess of 4×104 Da/s. In forward rf voltage scans, ion storage was considerably more reliable, with significant losses observed only at very high scan rates near the region qz=0.78 (hexapole resonance at βz=2/3).
Contemporary trends in the management of aortic stenosis in the USA (2019)

This nationwide survey documents the increasing incidence of AS interventions, the rising cost of modern AS care, and the paradigm shift in aortic valve replacement practice in the USA.
Improved voltage regulation strategies by PV inverters in LV rural networks (2012)

The growth of world energy demand and the environmental concerns lead to an increase of renewable energy production over the last decade. The increased number of grid-connected photovoltaic (PV) systems gave rise to problems concerning the stability and safety of the utility grid, as well as power quality issues. Lately, PV generators are required, according to the new German Grid Code (GC), to contribute to the grid stability and to provide grid classical functions during normal and abnormal operation. The purpose of this article is to investigate and optimize the standard voltage regulation methods for low voltage (LV) grid-connected PV systems. Reactive power supply strategy proposed by the German GC Q(U) is investigated and simulated performing load flow analysis on a European residential network benchmark. In order to improve the reactive power transfer in the system, an optimized algorithm of voltage regulation is designed with the aim of minimizing the losses in the system for a better integration of PV power generation into the grid.
CPM-FCM Joint Operation of a Nd: YAG Laser and Pulse Compression (1997)

We demonstrated the generation of femtosecond pulses from an LD-pumped Nd:glass fiber laser. A relatively long fiber was used to increase the Kerr effect in the fiber for passive modelocking, and the variation of the start-up threshold of modelocking with different lengths of fiber was investigated.
EGRAM – A Grammar Development Environment and its Usage for Language Generation (2004)

PP is used in a non-negligible proportion of non-intubated patients with COVID-19-related severe respiratory failure and is not associated with death but with ICU admission. The role of PP in this setting merits further evaluation in randomized studies.
Ultrafine Structure of Human Aortic Valve Calcific Deposits (2014)

Objective: To elucidate the mechanism of formation of calcific deposits inside the human natural heart valve based on their ultra-fine structure on nanometer scale observed by atomic force microscope.