gebhart/patrepeval huggingface dataset:
Joint Residual Stress/Refractive Index Characterization of Large-Mode-Area Erbium-Doped Fibers (2013)

The residual stress (RS) and refractive index (RI) distributions of large-mode-area (LMA) erbium-doped fibers (EDFs) are measured for the first time using a high-resolution three-dimensional index-stress distribution measurement method. The effects of fiber manufacturing, cleaving, and arc fusion splicing of a commercially available LMA EDF are concurrently characterized at state-of-the-art stress, index, and spatial resolutions. RS induced via fiber manufacturing results in RI changes as large as <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$1.2 \times 10^{-4}$</tex></formula> RI units through the photo-elastic effect. The relaxation of RS within <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">${\sim} 30$</tex></formula> <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$\mu$</tex> </formula> m of a cleaved end-face reverses the stress-induced RI changes formed during fiber manufacturing. After fusion splicing, an even larger stress-induced RI change of <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$3.5 \times 10^{-4}$</tex></formula> RI units results over an axial distance on the order of millimeters. The diffusion of core dopants reduces the maximum core RI by as much as 21.7% along a transition region length of <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex Notation="TeX">${\sim} 400$</tex></formula> <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex Notation="TeX">$\mu$</tex></formula> m. These measurements represent the first of many required to develop future ultra LMA EDFs where RS effects and dopant diffusion are absolutely critical for fiber design and performance.
Multi-velocity neural networks for gesture recognition in videos (2016)

We present a new action recognition deep neural network which adaptively learns the best action velocities in addition to the classification. While deep neural networks have reached maturity for image understanding tasks, we are still exploring network topologies and features to handle the richer environment of video clips. Here, we tackle the problem of multiple velocities in action recognition, and provide state-of-the-art results for gesture recognition, on known and new collected datasets. We further provide the training steps for our semi-supervised network, suited to learn from huge unlabeled datasets with only a fraction of labeled examples.
Light-Induced Proton Release by the Cyanobacterium Anabaena variabilis (1988)

Light-induced acidification by the cyanobacterium Anabaena variabilis is biphasic (a fast phase I and slow phase II) and shown to be sodium-dependent with an optimum concentration of 40 to 60 millimolar Na(+). Cells grown under low CO(2) concentrations at pH 9 (i.e. mainly HCO(3) (-) present in the medium) exhibited the slow phase II of proton efflux only, while cells grown under low CO(2) concentrations at pH 6.3 (i.e. CO(2) and HCO(3) (-) present) exhibited both phases. Light-induced proton release of phase I was dependent on inorganic carbon available in the bathing medium with an apparent K(m) for CO(2) of 20 to 70 micromolar. As was concluded from the CO(2) dependence of acidification measured at different pH of the bathing medium, bicarbonate inhibited phase-I acidification noncompetetively. Acidification was inhibited by acetazolamide, an inhibitor of carbonic anhydrase. Apparently, acidification of phase I is due to a light-dependent uptake of CO(2) being converted to HCO(3) (-) by a carbonic anhydrase-like function of the HCO(3) (-)-transport system (M Volokita, D Zenvirth, A Kaplan, L Reinhold 1984 Plant Physiol 76: 599-602) before or during entering the cell, thus releasing one proton per CO(2) converted to HCO(3) (-).
Efficient Search for Energetically Favorable Molecular Conformations against Metastable States via Gray-Box Optimization (2021)

In order to accurately understand and estimate molecular properties, finding energetically favorable molecular conformations is the most fundamental task for atomistic computational research on molecules and materials. Geometry optimization based on quantum chemical calculations has enabled the conformation prediction of arbitrary molecules, including <i>de novo</i> ones. However, it is computationally expensive to perform geometry optimizations for enormous conformers. In this study, we introduce the gray-box optimization (GBO) framework, which enables optimal control over the entire geometry optimization process, among multiple conformers. Algorithms designed for GBO roughly estimate energetically preferable conformers during their geometry optimization iterations. They then preferentially compute promising conformers. To evaluate the performance of the GBO framework, we applied it to a test set consisting of seven dipeptides and mycophenolic acid to determine their stable conformations at the density functional theory level. We thus preferentially obtained energetically favorable conformations. Furthermore, the computational costs required to find the most stable conformation were significantly reduced (approximately 1% on average, compared to the naive approach for the dipeptides).
Wireless Power Transmission to Organic Light Emitting Diode Lighting Panel with Magnetically Coupled Resonator (2012)

We are successful to lit the organic light emitting diode (OLED) lighting panel through the magnetically coupled wireless power transmission technology. For the wireless power transmission, we used the operation frequency 932 kHz, specially designed double spiral type transmitter, small and thin receiver on the four layered printed circuit board, and schottky diodes for the full bridge rectifier. Our white OLED is a hybrid type, in which phosphorescent and fluorescent organics are used together to generate stable white color. The total efficiency of power transmission is around 72%.
Downsizing of YVO4:Bi3+,Eu3+ Nanoparticles through Hydrophobization by Surface Modification with Primary Alkylamines (2012)

Abstract YVO4:Bi3+,Eu3+ nanoparticles (NPs) synthesized in water by wet chemical synthesis via citrate precursors are hydrophobized by surface modification with either oleylamine or octylamine and phase transfer into pentane phase. The dried hydrophobized NPs are redispersed well in nonpolar solvents containing oleic acid. Their hydrodynamic sizes are smaller than that of the hydrophilic NPs dispersed in water before the hydrophobization. The downsizing of NPs could be explained by releasing the aggregation of NPs through the hydrophobization process.
SARS-CoV-2 Spike protein suppresses CTL-mediated killing by inhibiting immune synapse assembly (2022)

Abstract CTL-mediated killing of virally infected or malignant cells is orchestrated at a specialized intercellular junction, the immune synapse (IS). We hypothesized that SARS-CoV-2 may target IS assembly in CTLs to escape killing. We show that primary human CD8 + T cells strongly upregulate the expression of ACE2, the Spike protein receptor, during differentiation to CTLs. CTL pre-incubation with the Wuhan or Omicron Spike variants inhibits IS assembly and function, as shown by defective synaptic accumulation of TCRs and tyrosine phosphoproteins as well as defective centrosome and lytic granule polarisation to the IS, resulting in impaired target cell killing. These defects were reversed by anti-Spike antibodies that interfere with ACE2 binding and were reproduced by ACE2 engagement with Angiotensin-II or an anti-ACE2 antibody, but not by the ACE2 product Ang (1-7). These results highlight a new strategy of immune evasion by SARS-CoV-2 based on the Spike-dependent, ACE2-mediated targeting of the lytic IS to prevent the elimination of infected cells. Summary statement We report a new mechanism of immune evasion by SARS-CoV-2 based on direct disabling CTLs to form immune synapses through Spike protein binding to ACE2. This mechanism could contribute to the failure of the immune system to control SARS-CoV-2 infection.
Categorization of Microwave Filters (2007)

This chapter contains sections titled: Introduction Minimum-Phase Microwave Filters Non-Minimum-Phase Symmetrical Response Microwave Filters Non-Minimum-Phase Asymmetrical Response Microwave Filters Conclusions References
Intramolecular carbopalladation of allylic amines and sulfides (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIntramolecular carbopalladation of allylic amines and sulfidesRobert A. Holton and Joseph R. ZoellerCite this: J. Am. Chem. Soc. 1985, 107, 7, 2124–2131Publication Date (Print):April 1, 1985Publication History Published online1 May 2002Published inissue 1 April 1985https://pubs.acs.org/doi/10.1021/ja00293a049https://doi.org/10.1021/ja00293a049research-articleACS PublicationsRequest reuse permissionsArticle Views643Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Structural Reorganization on Amorphous Ice Films below 120 K Revealed by Near-Thermal (∼1 eV) Ion Scattering (2008)

Topmost layers of amorphous ice undergo a structural transformation before the onset of crystallization and well before the premelting transitions. Ultralow-energy (∼1 eV) mass-selected Ar+ scattering has been used to detect this structural change. The transformation is manifested in the form of drastic changes in the scattered ion intensity in the ≤2 eV collision energy range. The changes are limited to the first few monolayers as larger thicknesses produce no additional effects. The technique becomes chemically sensitive but insensitive to the morphology and structure as the energy is increased above 3 eV. A similar behavior is observed with He+, Kr+, and a polyatomic ion, CH3+. Experiments revealed that the structural changes occurred only on amorphous ice and no such change occurred on crystalline ice. H2O and D2O ices behave similarly.
Effects of Microvascular Permeability Changes on Contrast-Enhanced T1 and Pharmacokinetic MR Imagings After Ischemia (2013)

Postischemic brain enhancement on routine CET1-WI seems to be closely related to the luxury reperfusion at the late subacute stage and is not dependent on microvascular permeability changes at the acute stage.
Intratumoral delivery of dendritic cells plus anti-HER2 therapy triggers both robust systemic antitumor immunity and complete regression in HER2 mammary carcinoma (2022)

HER2-DC1 i.t. with anti-HER2 antibodies mediates tumor regression through combined activation of T and B cell compartments and provides evidence that HER2-DC1 i.t. in combination with anti-HER2 antibodies can be tested as an effective alternative therapeutic strategy to current chemotherapy and anti-HER2 antibodies in HER2<sup>pos</sup> BC.
Suppression of Boron Penetration in P+-Poly-Si Gate Metal-Oxide-Semiconductor Transistor Using Nitrogen Implantation (1997)

The mechanism and the optimization of nitrogen implantation for suppression the boron penetration in p + -poly-Si gate metal-oxide-semiconductor capacitor is reported. This nitrogen co-implantation process exhibits a good suppression of boron penetration and a better electrical characteristic than that of control sample. It was found that nitrogen combines with the boron to form a B-N complex, retarding the penetration of boron itself, was identified by XPS measurements. The optimum nitrogen dosage is also found in this study.
DNA unwinding assay using streptavidin-bound oligonucleotides. (2006)

It is shown here that the use of a biotin-streptavidin complex as a helicase substrate improves helicase activity and the determination of helicase directionality. The method described is simpler that the currently available techniques.
Stimulatory and inhibitory influences of human immunodeficiency virus on normal B lymphocytes. (1986)

B-lymphocyte dysfunction is a characteristic feature of the acquired immunodeficiency syndrome (AIDS) and of the AIDS-related complex. The aim of the present study was to further examine the influences exercised by the human immunodeficiency virus (HIV; formerly called human T-lymphotropic virus type III or lymphadenopathy-associated virus, HTLV-III/LAV) on normal human B lymphocytes. An unfractionated protein preparation, made from HIV purified by density gradient centrifugation, was previously shown to induce differentiation of normal human B lymphocytes into immunoglobulin-secreting cells. In the present analyses, this B-lymphocyte response peaked on day 6 or 7 after culture initiation and was found to be independent of the requirement for monocytes but to require T cells. Responses could also be elicited in cultures of purified B cells by the addition of T cells that had been exposed to HIV antigen. Inhibitors of protein synthesis (puromycin and cycloheximide) abrogated the responses. In contrast to its stimulatory effects, the same virus preparation was previously shown to inhibit polyclonal responses that are normally elicited in peripheral blood lymphocyte cultures by a T-dependent stimulus (pokeweed mitogen) and T-independent stimulus (Epstein-Barr virus). The present studies suggest that the inhibitory effects of the HIV antigen studied herein are targeted primarily at the B lymphocytes. The role of T lymphocytes in the HIV antigen-mediated inhibitory effects, although demonstrated, could not be conclusively established as an essential pathway. These findings elucidate mechanisms by which components of HIV exert stimulatory as well as inhibitory effects on human B lymphocytes and thereby lead to the dysfunction of these cells in HIV infection.
Design and Synthesis of Sodium Ion-Selective Ionophores Based on 16-Crown-5 Derivatives for an Ion-Selective Electrode (1996)

To develop an ionophore that is highly selective for sodium for use in an ion-selective electrode, we propose a model based on 16-crown-5 which has a cavity just the size of Na(+ )and has a "block" subunit to prevent complex formation with ions larger than Na(+). Based on this molecular model, eight kinds of 16-crown-5 derivatives have been synthesized, and their structural ion selectivity has been evaluated in detail. The 16-crown-5 derivatives having two bulky "block" subunits showed high Na(+) selectivity relative to K(+). In particular, the derivative with two decalino subunits (DD16C5) exhibited the highest Na(+) selectivity of all the ionophores examined. When a phosphate ester-type membrane plasticizer, tris(ethylhexyl) phosphate, was used as the membrane solvent for the ion-sensing membrane based on poly(vinyl chloride), the electrode using DD16C5 exhibited a Na(+) selectivity of over 1000 times relative to alkali metal and alkaline earth metal ions, including K(+), which is the most serious interferant. The evaluation of the relationship between the ionophore chemical structures and the ion-selective features contributes to the host-guest chemistry to give a highly selective ionophore for an alkali metal ion.
Analytical Methods in Combinatorial Chemistry By Bing Yan. Technomic Publishing Company, Inc., Lancaster, PA. 2000. xv + 268 pp. 15.5 × 23.5 cm. ISBN 1-56676-809-8. $199.95. (2001)

ADVERTISEMENT RETURN TO ISSUEPREVBook ReviewNEXTAnalytical Methods in Combinatorial Chemistry By Bing Yan. Technomic Publishing Company, Inc., Lancaster, PA. 2000. xv + 268 pp. 15.5 × 23.5 cm. ISBN 1-56676-809-8. $199.95.Jan W. F. WasleyView Author Information Neurogen Corporation 35 NE Industrial Road Branford, Connecticut 06405Cite this: J. Med. Chem. 2001, 44, 20, 3334Publication Date (Web):August 28, 2001Publication History Published online28 August 2001Published inissue 1 September 2001https://pubs.acs.org/doi/10.1021/jm010201thttps://doi.org/10.1021/jm010201tbook-reviewACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views40Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Combinatorial chemistry,Materials,Nuclear magnetic resonance spectroscopy,Optimization,Organic polymers Get e-Alerts
High‐Performance Doped Silver Films: Overcoming Fundamental Material Limits for Nanophotonic Applications (2017)

The field of nanophotonics has ushered in a new paradigm of light manipulation by enabling deep subdiffraction confinement assisted by metallic nanostructures. However, a key limitation which has stunted a full development of high-performance nanophotonic devices is the typical large losses associated with the constituent metals. Although silver has long been known as the highest quality plasmonic material for visible and near infrared applications, its usage has been limited due to practical issues of continuous thin film formation, stability, adhesion, and surface roughness. Recently, a solution is proposed to the above issues by doping a proper amount of aluminum during silver deposition. In this work, the potential of doped silver for nanophotonic applications is presented by demonstrating several high-performance key nanophotonic devices. First, long-range surface plasmon polariton waveguides show propagation distances of a few centimeters. Second, hyperbolic metamaterials consisting of ultrathin Al-doped Ag films are attained having a homogeneous and low-loss response, and supporting a broad range of high-k modes. Finally, transparent conductors based on Al-doped Ag possess both a high and flat transmittance over the visible and near-IR range.
SRPerf: A Performance Evaluation Framework for IPv6 Segment Routing (2020)

Segment Routing (SR) is a form of loose source routing. It provides the ability to include a list of instructions, called segments, in the packet header. The SR architecture has been first implemented with the MPLS (SR-MPLS) data plane and then, quite recently, with the IPv6 data plane (SRv6). SRv6 is a promising solution to support advanced services such as Traffic Engineering, Service Function Chaining and Virtual Private Networks. The SRv6 data plane is supported in many different software forwarding engines including the Linux kernel and the Vector Packet Processor (VPP), as well as in hardware devices. In this article, we present SRPerf, a performance evaluation framework for software and hardware implementations of SRv6. SRPerf is able to perform different benchmarking tests such as throughput and latency. The architecture of SRPerf can be easily extended to support new benchmarking methodologies as well as different SRv6 implementations. We have used SRPerf to evaluate the performance of two SRv6 implementations: Linux kernel and VPP. SRPerf is a valuable tool in the context of modern forwarding engines where new features can be added at fast pace, as it helps experimenters to validate their work. In this work, we have leveraged SRPerf to validate the implementation of some SRv6 behaviors in the Linux kernel and we have discovered and fixed some implementation flaws, making available the fixed code.
Resource-aware architectures for adaptive particle filter based visual target tracking (2013)

There are a growing number of visual tracking applications now being envisioned for mobile devices. However, since computer vision algorithms such as particle filtering have large computational demands, they can result in high energy consumption and temperatures in mobile devices. Conventional approaches for distributed target tracking with a camera node and a receiver node are either sender-based (SB) or receiver-based (RB). The SB approach uses little energy and bandwidth, but requires a sender with large computational resources. The RB approach fits applications where computational resources are completely unavailable to the sender, but requires very large energy and bandwidth. In this article, we propose three architectures for distributed particle filtering that (i) reduce particle filtering workload and (ii) allow for dynamic migration of workload between nodes participating in tracking. We also discuss an adaptive particle filtering extension that adapts particle filter computational complexity and can be applied to both the conventional and proposed architectures for improved energy efficiency. Results show that the proposed solutions require low additional overhead, improve on tracking system lifetime, balance node temperatures, maintain track of the desired target, and are more effective than conventional approaches in many scenarios.