gebhart/patrepeval huggingface dataset:
IBM zEnterprise energy management (2012)

Data centers are facing serious energy challenges. Increasing energy costs make the operation and cooling of servers more significant cost factors. Furthermore, improvements in technology have led to processor chips and systems with rapidly increasing power density. The resulting power consumption and cooling requirements of these systems are pushing many existing data centers to the limits of their power distribution capability and cooling capacity. Improvements in energy efficiency and management are needed at the chip and the system level to counteract this trend. This paper provides a comprehensive description of the hardware and firmware improvements implemented with IBM zEnterprise® 196 to stop the growth of and even reduce its energy footprint compared with previous IBM System z® servers. These include more power-efficient chips; power conversion and distribution; new sensors; cooling control firmware; new energy management functions; integrated hybrid energy management for power saving and power capping across the whole hybrid system; and data center energy-efficiency improvements resulting from options for water cooling, high-voltage DC (HVDC) power, and overhead cabling.
Identification of InuR, a new Zn(II)2Cys6 transcriptional activator involved in the regulation of inulinolytic genes in Aspergillus niger (2007)

The expression of inulinolytic genes in Aspergillus niger is co-regulated and induced by inulin and sucrose. We have identified a positive acting transcription factor InuR, which is required for the induced expression of inulinolytic genes. InuR is a member of the fungal specific class of transcription factors of the Zn(II)2Cys6 type. Involvement of InuR in inulin and sucrose metabolism was suspected because of the clustering of inuR gene with sucB, which encodes an intracellular invertase with transfructosylation activity and a putative sugar transporter encoding gene (An15g00310). Deletion of the inuR gene resulted in a strain displaying a severe reduction in growth on inulin and sucrose medium. Northern analysis revealed that expression of inulinolytic and sucrolytic genes, e.g., inuE, inuA, sucA, as well as the putative sugar transporter gene (An15g00310) is dependent on InuR. Genome-wide expression analysis revealed, three additional putative sugar transporters encoding genes (An15g04060, An15g03940 and An17g01710), which were strongly induced by sucrose in an InuR dependent way. In silico analysis of the promoter sequences of strongly InuR regulated genes suggests that InuR might bind as dimer to two CGG triplets, which are separated by eight nucleotides.
Endoscopic laser treatment (1977)

Abstract The purpose of this study is to evaluate the efficacy and safety of a new argon laser system for stopping bleeding from experimental canine gastric ulcers. This system consists of a catheter which can be inserted via an endoscopic biopsy channel to deliver a jet of CO 2 coaxially with an argon laser beam. The efficacy of this system in stopping bleeding was tested in two acute experiments at laparotomy in heparinized dogs using our gastric ulcer model. At 7 w of power the gas-jet-assisted laser proved 100% effective in stopping bleeding with an average of three 5-sec exposures, as compared to the same laser without added CO 2 , which required an average of 11 5-sec exposures. Furthermore, the 7-w laser without added CO 2 did not stop all bleeding ulcers. The safety of the CO 2 laser system was tested in a chronic experiment at sterile laparotomy using the same ulcer model. No ulcer treated with the 7-w gas-jet-assisted argon laser showed histologic evidence of full thickness injury. A final acute experiment compared the efficacy of various wattages of the gas-jet-assisted laser in stopping bleeding from the ulcer model; the wattages used in this series of experiments and in previous experiments proved to be in the efficacious range. We conclude that CO 2 added coaxially to a 6- to 7-w argon laser increases the efficacy of coagulation while reducing the depth of injury.
Inertial Navigation Aiding by Stationary Updates (2011)

Sensor-aided inertial navigation has successfully been used for decades for localization of a roving body. When the rover is known to be stationary, artificial “stationary” measurements (i.e., zero velocity and/or zero angular rate) may be imposed. This corrects the velocity, attitude, and inertial measurement unit (IMU) biases, which decreases the rate of drift of the position and attitude. Implementation requires reliable automated tests to detect periods when the vehicle is stationary. Due to cost concerns, methods that use sensors that are already on the vehicle are preferred. This paper reviews existing stationary detection methods and proposes a new frequency domain approach, using only IMU data, to detect stationarity, with specifications and analysis for land vehicles. The performance of this new approach is evaluated in both theory and practice. In addition, this paper presents analytic and numeric evaluations of the observability of the inertial navigation system (INS) error states with stationary updates. Improvements in localization performance in an INS with stationary detection and aiding is shown experimentally.
Design of an MWW zeolite catalyst for linear alkylbenzene synthesis with improved catalytic stability (2016)

Effect of micro–meso porosity of MWW zeolites on the catalytic linear alkylbenzene synthesis was studied.
Development of Grade X80 High Charpy Energy Linepipe by MA Formation Control (2016)

Higher grade linepipes such as grade X80 have been developed and applied to long distance pipelines in order to reduce the cost of pipeline construction by using thinner pipes than is possible with conventional grades. Service pressures have also been increased in recent years for efficient gas transportation. In addition to the requirement of higher strength, running ductile fracture should be prevented in long distance and high pressure pipelines. Resistance to ductile fracture, as evaluated by Charpy energy, is an important material property for higher grade linepipes. It has been reported that bainite single-phase steel tends to show higher Charpy energy than ferrite-bainite or bainite-MA (martensite-austenite constituent) dual-phase steels, since void nucleation is suppressed in single-phase steels compared with dual-phase steels. However, in higher grade steels with a bainite single phase, a small amount of MA grains generally remains due to the chemical stability of MA. Therefore, further reduction of MA is key to improving Charpy energy for higher grade linepipe steels. In order to achieve high Charpy energy by MA formation control, the optimum conditions of the plate manufacturing process were investigated. As a result, a high Charpy energy was achieved by the combination of controlled rolling and precise control of the accelerated cooling conditions, by which the MA phase was minimized. Based on the above investigation, grade X80 high Charpy energy linepipes were trial-produced by applying JFE Steel’s optimized accelerated cooling (ACC) system with a high cooling rate and homogeneous temperature profile. Stable higher Charpy energy was achieved by minimizing MA formation and achieving a homogeneous microstructure by advanced cooling control.
Providing Network Time Protocol Based Timing for Smart Grid Measurement and Control Devices in 5G Networks (2019)

Smart grids are key enablers for creating sustainable energy systems. On the other hand, they introduce a grid management challenge as power grids become more complex and dynamic. Evolving power grids towards smart grids requires combining electric energy technology with communications and information technology. In a distributed network, time synchronization is often one central question. This paper studies limitations of utilizing the widely used Network Time Protocol (NTP) in current 4G cellular networks for smart grid management. As a specific contribution, an improved, NTP based clock adjustment algorithm is proposed to provide more accurate timing information. Finally, the paper studies capabilities of emerging 5G cellular networks to further improve accuracy of timing provided to user equipment (UE).
Emergence of a New Creutzfeldt-Jakob Disease: 26 Cases of the Human Version of Mad-Cow Disease, Days After a COVID-19 Injection (2023)

Creutzfeldt-Jakob Disease, the formerly rare but universally fatal prion disease in humans, normally progresses over several decades before it leads to death. In the Appendix to this paper, we highlight the presence of a prion region in the spike protein of the original SARS-CoV-2, and in all the “vaccine” variants built from the Wuhan virus. The prion region in the spike of SARS-CoV-2 has a density of mutations eight times greater than that of the rest of the spike, and, yet, strangely that entire prion region disappears completely in the Omicron variant. In the main body of our text, we present 26 cases of Creuzfeldt-Jacob Disease, all diagnosed in 2021 with the first symptoms appearing within an average of 11.38 days after a Pfizer, Moderna, or AstraZeneca COVID-19 injection. Because the causal progression, the etiopathogenesis, of these atypical and new cases of human prion disease — cases of what is apparently a totally new form of rapidly developing Creuzfeldt-Jacob Disease — we focus on the chronology of the symptomatic development. We consider it from an anamnestic point of view — one in which we compare the typical development of pre-COVID cases of Creuzfeldt-Jacob Disease to the extremely accelerated development of similar symptoms in the 26 cases under examination. By such an approach, we hope to work out the etiopathogenesis critical to understanding this new and much more rapidly developing human prion disease. By recalling the sequential pathway of that the formerly subacute and slowly developing disease followed in the past, and by comparing it with this new, extremely acute, rapidly developing prion disease — one following closely after one or more of the COVID-19 injections — we believe it is correct to infer that the injections caused the disease in these 26 cases. If so, they have probably also caused a many other cases that have gone undiagnosed because of their rapid progression to death. By late 2021, 20 had died within 4.76 months of the offending injection. Of those, 8 died suddenly within 2.5 months confirming the rapid progression of this accelerated form of Creuzfeldt-Jacob Disease. By June 2022, 5 more patients had died, and at the time of this current writing, only 1 remains still alive.
Analysis of Optimum Sheet Resistance for Integrated Electromagnetic Noise Suppressors (2006)

This paper discusses the physical nature of the optimum sheet resistance of noise suppression sheets/films based on three-dimensional (3-D) finite-element method (FEM) electromagnetic field simulation. Co-Al-O films with sheet resistance of10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> -10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sup> Omega/square were deposited on top of a micro strip-line. It was revealed that inline loss generation was maximized with the film's sheet resistance of nominally 100 Omega/square, which explains well the earlier experimental results. The ratio of loss generation to the input power reached 0.96 in the experimental results and 0.97 in the simulation results at 6 GHz. A certain balance of eddy current generation and a material resistivity allowed the Co-Al-O film to dissipate the inline noise power effectively. The simulation results also showed that the inline power was not radiated from the Co-Al-O film but was lost in the film. Ferromagnetic resonance losses were found around 1-2 GHz combined with the eddy current losses. These two electric and magnetic losses enhanced total inline loss generation effectively
Spectroscopic characteristics of chromium doped mullite glass-ceramics (1988)

Characteristics of chromium-doped mullite ceramics are discussed with reference to possible laser applications. Dominant features are attributed to large and inherent spectroscopic inhomogeneity of mullite. The spectroscopic data are analyzed using a generalized McCumber theory. The peak stimulated emission cross section is 0.54*10/sup -20/ cm/sup 2/. This, together with preliminary single-pass measurements, indicate that gain for mullite is bout 2.6 times smaller than gain for alexandrite.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Novel Splice Variants of Rat CaV2.1 That Lack Much of the Synaptic Protein Interaction Site Are Expressed in Neuroendocrine Cells (2008)

Voltage-gated Ca(2+) channels are responsible for the activation of the Ca(2+) influx that triggers exocytotic secretion. The synaptic protein interaction (synprint) site found in the II-III loop of Ca(V)2.1 and Ca(V)2.2 mediates a physical association with synaptic proteins that may be crucial for fast neurotransmission and axonal targeting. We report here the use of nested PCR to identify two novel splice variants of rat Ca(V)2.1 that lack much of the synprint site. Furthermore, we compare immunofluorescence data derived from antibodies directed against sequences in the Ca(V)2.1 synprint site and carboxyl terminus to show that channel variants lacking a portion of the synprint site are expressed in two types of neuroendocrine cells. Immunofluorescence data also suggest that such variants are properly targeted to neuroendocrine terminals. When expressed in a mammalian cell line, both splice variants yielded Ca(2+) currents, but the variant containing the larger of the two deletions displayed a reduced current density and a marked shift in the voltage dependence of inactivation. These results have important implications for Ca(V)2.1 function and for the mechanisms of Ca(V)2.1 targeting in neurons and neuroendocrine cells.
Understanding deep convolutional networks (2016)

Deep convolutional networks provide state-of-the-art classifications and regressions results over many high-dimensional problems. We review their architecture, which scatters data with a cascade of linear filter weights and nonlinearities. A mathematical framework is introduced to analyse their properties. Computations of invariants involve multiscale contractions with wavelets, the linearization of hierarchical symmetries and sparse separations. Applications are discussed.
Computer aided design of microwave equalizers using the real frequency method application to the design of high flow radar communications receiver (2004)

Receiver design for digital radar and optical communication involves optimization and realization of an equalizing filter to provide a suitable signal at the input to the decision circuit. A frequently encountered problem in filter design is the realization of a network with a specified frequency transfer characteristic. In this paper, the optimization of band pass characteristics is considered. Our approach is to approximate the target by the real frequency (RF) method, which gives directly the elements of the equalizing filter. The method is illustrated by the design of a filter for a radar communications receiver.
Molecular analysis of T-cell receptor repertoire in bone marrow transplant recipients: evidence for oligoclonal T-cell expansion in graft-versus-host disease lesions (1996)

We have analyzed the T-cell receptor (TCR) V beta repertoire using polymerase chain reaction (PCR) in a cohort of eight patients receiving allogeneic bone marrow transplantation (BMT) from related and unrelated donors at the City of Hope. Results of PCR studies from graft-versus-host disease (GVHD) skin lesions show a bias in the usage of TCR V beta families, whereas examination of peripheral blood (PB) withdrawn at the same time did not reveal a similar phenomenon. In one such family, TCR V beta 2 is predominantly expressed in 7 of 7 biopsy specimens examined. V beta 2 TCR expression from these patients was analyzed more extensively using a combination of individual TCR gene cloning, followed by sequence analysis. We found evidence of oligoclonal expansion of single V beta 2-bearing TCRs in GVHD lesions, and in the PB of some patients after diagnosis of GVHD. In contrast, GVHD-negative biopsy samples showed no evidence for clonotypic TCR amplification. Sequence-specific TCR CDR3 region probes were derived from analysis of the predominant expressed TCR in GVHD lesions, and used to probe Southern blots of amplified V beta 2 TCR mRNA from PB and tissue from BMT recipients and their respective donors. In most cases the probes are highly specific in detecting TCR expression from GVHD lesions alone, although in several instances expression could be detected in PB after GVHD diagnosis. These data provide supporting evidence for the hypothesis that acute GVHD is associated with expansion of T-cell clones expressing antigen-specific TCRs that may contribute to the disease pathology.
An HTTP/2 push-based framework for low-latency adaptive streaming through user profiling (2018)

Web portals, such as the one hosted by news providers, have recently started to provide significant amounts of multimedia content.To deliver this content over the best-effort Internet, HTTP Adaptive Streaming (HAS) is generally used, allowing smoother playback and a better Quality of Experience (QoE).To stimulate user engagement with the provided content, reducing the video's startup time has become more and more important: while the current median video load time is in the order of seconds, research has shown that user waiting times must remain below two seconds to achieve an acceptable QoE.In this work, we present a framework for low-latency delivery of news-related video content, integrating four optimizations either at server-side, client-side, or at the application layer.Most importantly, we propose to identify relevant content through user profiling, using proactive delivery and client-side caching to reduce the video startup time.By means of a large data set from a Belgian news provider, we show that the proposed framework can reduce the startup time from 4.6 s to 1.5 s (-74.6%) in a 3G scenario, at the cost of limited network overhead and additional complexity at server-and client-side.
Distributed Optimal Beamformers for Cognitive Radios Robust to Channel Uncertainties (2012)

Through spatial multiplexing and diversity, multi-input multi-output (MIMO) cognitive radio (CR) networks can markedly increase transmission rates and reliability, while controlling the interference inflicted to peer nodes and primary users (PUs) via beamforming. The present paper optimizes the design of transmit- and receive-beamformers for ad hoc CR networks when CR-to-CR channels are known, but CR-to-PU channels cannot be estimated accurately. Capitalizing on a norm-bounded channel uncertainty model, the optimal beamforming design is formulated to minimize the overall mean-square error (MSE) from all data streams, while enforcing protection of the PU system when the CR-to-PU channels are uncertain. Even though the resultant optimization problem is non-convex, algorithms with provable convergence to stationary points are developed by resorting to block coordinate ascent iterations, along with suitable convex approximation techniques. Enticingly, the novel schemes also lend themselves naturally to distributed implementations. Numerical tests are reported to corroborate the analytical findings.
Prostate Tumor Cells Infected with a Recombinant Influenza Virus Expressing a Truncated NS1 Protein Activate Cytolytic CD8 + Cells To Recognize Noninfected Tumor Cells (2005)

Many viral oncolytic approaches against cancer are based on the ability of specific viruses to replicate in tumors expressing components of the constitutively activated Ras/mitogen-activated protein kinase (MAPK) pathways and/or inhibited or dysregulated alpha/beta interferon (IFN-alpha/beta) response pathways. A major issue when considering these approaches is their applicability to tumors that lack activated Ras. To identify the effector mechanisms activated by oncolytic viruses, we investigated inhibition of proliferation of the prostate cancer line LNCap by the recombinant TR-NS1 influenza A virus, a genetically attenuated influenza A/PR8/34 virus expressing a truncated nonstructural protein (NS1) of 126 amino acids. LNCap cells lack constitutively activated MAPK, extracellular signal-regulated kinase (ERK), and p38 and are resistant to death by IFN-alpha. Truncation of the NS1 protein of influenza viruses is known to result in viral attenuation due to a reduced ability of the NS1 to inhibit the IFN-alpha/beta response. Infection with TR-NS1 virus rapidly activated ERK-1 more than ERK-2 in LNCap cells. Importantly, TR-NS1 virus infection transiently inhibited cell proliferation and induced apoptosis in LNCap cells. Addition of peripheral blood mononuclear cells (PBMC) and interleukin 12 (IL-12) to TR-NS1 virus-infected LNCap cells (TR-NS1-LNCap) resulted in faster elimination of TR-NS1-LNCap cells compared with LNCap cells. Moreover, TR-NS1-LNCap cells induced IFN-gamma in PBMC. The levels of IFN-gamma were amplified by IL-12. TR-NS1-LNCap cells also induced tumor-lytic cytotoxic T lymphocytes (CTL). These CTL lysed noninfected LNCap cells in a CD8-dependent manner. Activation of cellular immunity to tumor cells by viruses is an intriguing effector pathway, which should be especially significant for elimination of human tumors that lack activated Ras.
Low-Harmonics Three-Phase Power Conditioner for hotovoltaic Integration (2010)

This paper describes the design of a power conditioning unit (PCU) for photovoltaic power system to be interconnected with the utility grid (UG). The proposed PCU employs six-pulse three-phase inverter with modified-sinusoidal-pulse- width-modulation (MSPWM) switching technique, a parallel and series filters and an efficient control of dc to ac power conversion. The parallel and series filters are designed for both harmonics reduction and power factor correction. The efficient control of dc to ac power conversion makes the inverter output voltage immune to the variation in the dc voltage. The proposed PCU has been studied with both equation solving and extensive simulations. A 5 MW PCU has been designed and its performance has been investigated in detail.
Understanding and Supporting Sensemaking in Collaborative Web Search (2009)

While there has been some research on sensemaking in individual information seeking, there is little understanding of sensemaking in collaborative information seeking tasks, such as collaborative Web search. We conducted a study of users ’ sensemaking in collaborative Web search tasks performed using SearchTogether. Based on findings of this study, we designed, implemented, and evaluated a tool, CoSense, to enhance sensemaking for collaborative search tasks. The results of our evaluation of CoSense provide insight into how people collaboratively make sense of information and what design features can help them.