gebhart/patrepeval huggingface dataset:
Solution-Focused Brief Therapy and Students' Behaviors (2019)

Around 17 million children in the U.S have or have had a behavioral health issue, but most are not treated. Eighty percent of children with anxiety are not receiving treatment, along with 40% of children with diagnosable ADHD/ADD and 60% of children with diagnosable depression. Untreated behavioral health issues have had a severe impact on the nation's economy. According to the National Alliance on Mental Illness, untreated behavioral health issues cost about $100 billion a year in lost productivity. The United States has a high population of both children and adults with untreated behavioral health issues. Children who have untreated behavioral health issues, can potentially grow up to be adults with behavioral health issues. The start of many behavioral health conditions most often occurs in adolescence. Half of individuals living with behavioral health issues experience onset by the age of 14. This number jumps to 75% by the age of 24. Untreated or inadequately treated behavioral health conditions can affect a student's ability to learn, grow and develop. Even during the best of economic times, youth living with behavioral health issues struggle to access essential behavioral health services and supports. Services are often unavailable or inaccessible for those who need them the most. There is a need for students to have better access to behavioral health services which can be offered within the school setting. Schools should not wait for a crisis to occur within a school, (e.g., a school shooting) before addressing the lack of behavioral health services for students. The research question for this study is: Will students' behaviors differ significantly, as measured by the pretest and post test BRIC, based upon participation in SFBT?
Low shear process for producing polymer composite fibers (2023)

A method for producing a polymer composite fiber comprised of a polymer matrix with filaments incorporated therein whose lengthwise dimensions are substantially oriented with the axial dimension of the composite fiber, the method comprising subjecting a melt comprised of a polymer matrix and filaments to an extrusion process in which the melt is extruded into a fibrous form in the absence of screw extruders and in the substantial absence of shear forces that result in breakage of the filaments, followed by cooling and solidification of the extruded melt to provide the polymer composite fiber. Integration of these polymer composite fibers with additive manufacturing technologies, particularly rapid prototyping methods, such as FFF and 3D printing, are also described. The resulting polymer composite fibers and articles made thereof are also described.
Posttranslational modification of ras proteins: Detection of a modification prior to fatty acid acylation and cloning of a gene responsible for the modification (1988)

Products of ras genes are synthesized as precursors in the cytosol and transported to the plasma membrane by a process which involves posttraslational modification by fatty acid. In this paper, we present evidence for the occurrence in the cytosol of an intermediate modification of ras proteins prior to the fatty acid acylation. The modification is detected by a slight shift in the mobility of the protein on SDS polyacrylamide gel. The fatty acid acylation does not contribute to this mobility shift. This modification is affected by the dprl mutation which has recently been shown to affect the processing of yeast RAS proteins. To further characterize the nature of the modification event, we have cloned DPR1 gene from the DNA of Saccharomyces cerevisiae. The gene is actively transcribed in yeast cells producing mRNA of approximately 1.6 kb. Genes related to the DRP1 appear to be present in a distantly related yeast, Schizosaccharomyces pombe as well as in guinea pig and human cells.
Phase Noise Measurements of AlN Contour-Mode Resonators (2016)

International audience
The Therapeutic Use of Zinc in Macular Degeneration (1989)

To the Editor. —We read the article by Dr Newsome and colleagues 1 with great interest. It was very exciting to learn that in such a well-designed, well-executed, and well-analyzed controlled study, zinc therapy had such a marked effect on reducing the progression of such an important and debilitating disease as macular degeneration. However, we were dismayed by the authors' emphasis on possible zinc toxicity. In their own terms, their abstract closes with, Because of the pilot nature of the study and the possible toxic effects and complications of oral zinc administration, widespread use of zinc in macular degeneration is not now warranted. Elsewhere in the report the authors expresspecific concerns about anemia and worsening of cardiovascular disease. Our dismay arises from our team having spent the last 20 years administering zinc in relatively high doses to various types of patients and having a very difficult time identifying toxic effects.
Automatic cone photoreceptor segmentation using graph theory and dynamic programming (2013)

Geometrical analysis of the photoreceptor mosaic can reveal subclinical ocular pathologies. In this paper, we describe a fully automatic algorithm to identify and segment photoreceptors in adaptive optics ophthalmoscope images of the photoreceptor mosaic. This method is an extension of our previously described closed contour segmentation framework based on graph theory and dynamic programming (GTDP). We validated the performance of the proposed algorithm by comparing it to the state-of-the-art technique on a large data set consisting of over 200,000 cones and posted the results online. We found that the GTDP method achieved a higher detection rate, decreasing the cone miss rate by over a factor of five.
Self-Healing of Unentangled Polymer Networks with Reversible Bonds (2013)

Self-healing polymeric materials are systems that after damage can revert to their original state with full or partial recovery of mechanical strength. Using scaling theory we study a simple model of autonomic self-healing of unentangled polymer networks. In this model one of the two end monomers of each polymer chain is fixed in space mimicking dangling chains attachment to a polymer network, while the sticky monomer at the other end of each chain can form pairwise reversible bond with the sticky end of another chain. We study the reaction kinetics of reversible bonds in this simple model and analyze the different stages in the self-repair process. The formation of bridges and the recovery of the material strength across the fractured interface during the healing period occur appreciably faster after shorter waiting time, during which the fractured surfaces are kept apart. We observe the slowest formation of bridges for self-adhesion after bringing into contact two bare surfaces with equilibrium (very low) density of open stickers in comparison with self-healing. The primary role of anomalous diffusion in material self-repair for short waiting times is established, while at long waiting times the recovery of bonds across fractured interface is due to hopping diffusion of stickers between different bonded partners. Acceleration in bridge formation for self-healing compared to self-adhesion is due to excess non-equilibrium concentration of open stickers. Full recovery of reversible bonds across fractured interface (formation of bridges) occurs after appreciably longer time than the equilibration time of the concentration of reversible bonds in the bulk.
Formulating a Natural Colorant Containing Wax for a One-step Color-add Application for Fresh Citrus (2017)

In Florida, early season citrus fruits usually reach full maturity in terms of internal quality while their peel often does not turn to orange color after degreening due to insufficient buildup of carotenoids. For huanglongbing (HLB)-affected orange trees, the fruit may never turn orange during the entire harvest season, despite any cold weather. Improvement of early season citrus peel color is important to the citrus industry to better meet consumer expectations. Occasionally, packinghouses apply a dye, Citrus Red No. 2 (CR2), to improve the surface color of oranges, temples, and tangelos before applying a fruit wax to impart shine, retain moisture, and slow fruit senescence. In a previous report, we determined that paprika and annatto extracts are comparable to CR2 as natural colorant alternatives. In this research, the goal was to formulate a natural colorant [annatto, paprika, or paprika oleoresin (PO)]-containing carnauba wax coating. The coatings were first evaluated for color, shine, moisture retention, respiration rate, ethylene production, and internal gas content. Control fruit were coated with carnauba wax alone, or dyed with CR2 then coated with carnauba wax. The effects were assessed under different temperature and light exposure conditions to simulate commercial storage and marketing. The results showed that a one-step application of paprika-containing carnauba wax was comparable to the two-step (“CR2 then wax”) applications in improving fruit appearance and modification of internal gas composition.
Harnessing bursty interference (2009)

Interference is a central feature of wireless communication. In many scenarios, interference is bursty: interfering wireless links come and go. Designing the system assuming interference to be always present is very conservative. In this paper, we take a fundamental information theoretic stand point and address the issue of statistical gain associated with bursty interference in the context of a pair of unicast interfering wireless links. Modeling the problem as a ldquodegraded message setrdquo two user Gaussian interference channel, we approximately characterize the symmetric capacity region. Our results demonstrate the fundamental existence of three regimes: one where treating interference as always there is without loss of optimality, another where one can harness as well as if interference was never there and a third where the performance is in between these two regimes.
Atomic resolution duplex structure of the simplified nucleic acidGNA (2009)

Double helix variations of glycol nucleic acids (GNA) are revealed by the atomic resolution crystal structure of a 6mer GNA duplex containing solely Watson-Crick type hydrogen-bonded base pairs.
Correlation and Error Metrics for Plant Identification of On-Orbit Space Structures (2007)

Covers advancements in spacecraft and tactical and strategic missile systems, including subsystem design and application, mission design and analysis, materials and structures, developments in space sciences, space processing and manufacturing, space operations, and applications of space technologies to other fields.
Large Scale Bayes Point Machines (2000)

The concept of averaging over classifiers is fundamental to the Bayesian analysis of learning. Based on this viewpoint, it has recently been demonstrated for linear classifiers that the centre of mass of version space (the set of all classifiers consistent with the training set) --- also known as the Bayes point --- exhibits excellent generalisation abilities. However, the billiard algorithm as presented in [4] is restricted to small sample size because it requires O \\Gamma m 2 \\Delta of memory and O \\Gamma N \\Delta m 2 \\Delta computational steps where m is the number of training patterns and N is the number of random draws from the posterior distribution. In this paper we present a method based on the simple perceptron learning algorithm which allows to overcome this algorithmic drawback. The method is algorithmically simple and is easily extended to the multi-class case. We present experimental results on the MNIST data set of handwritten digits which show that ...
Bayesian Decision Trees via Tractable Priors and Probabilistic Context-Free Grammars (2023)

Decision Trees are some of the most popular machine learning models today due to their out-of-the-box performance and interpretability. Often, Decision Trees models are constructed greedily in a top-down fashion via heuristic search criteria, such as Gini impurity or entropy. However, trees constructed in this manner are sensitive to minor fluctuations in training data and are prone to overfitting. In contrast, Bayesian approaches to tree construction formulate the selection process as a posterior inference problem; such approaches are more stable and provide greater theoretical guarantees. However, generating Bayesian Decision Trees usually requires sampling from complex, multimodal posterior distributions. Current Markov Chain Monte Carlo-based approaches for sampling Bayesian Decision Trees are prone to mode collapse and long mixing times, which makes them impractical. In this paper, we propose a new criterion for training Bayesian Decision Trees. Our criterion gives rise to BCART-PCFG, which can efficiently sample decision trees from a posterior distribution across trees given the data and find the maximum a posteriori (MAP) tree. Learning the posterior and training the sampler can be done in time that is polynomial in the dataset size. Once the posterior has been learned, trees can be sampled efficiently (linearly in the number of nodes). At the core of our method is a reduction of sampling the posterior to sampling a derivation from a probabilistic context-free grammar. We find that trees sampled via BCART-PCFG perform comparable to or better than greedily-constructed Decision Trees in classification accuracy on several datasets. Additionally, the trees sampled via BCART-PCFG are significantly smaller -- sometimes by as much as 20x.
Effective Cancer Targeting Using an Anti‐tumor Tissue Vascular Endotheliumspecific Monoclonal Antibody (TES‐23) (2000)

Immunoconjugate targeting of solid tumors has not been routinely successful because the endo-thelial cells of blood vessels act as a physical barrier against the transport of macromolecules, such as antibodies. In the present study, we attempted to achieve tumor vascular targeting with an anti-tumor tissue endothelium-specific monoclonal antibody (TES-23). TES-23, an IgG1 monoclonal antibody raised against rat KMT-17 fibrosarcoma-derived endothelial cells, was covalently conjugated with neocarzinostatin (NCS) in a previous study. The TES-23-NCS conjugate induced tumor hemorrhagic necrosis, and showed marked anti-tumor effects against rat KMT-17 fibrosarcoma. This result prompted us to investigate whether this approach would be applicable to various other types of solid tumors. One hour after injection of (125)I-labeled TES-23 into BALB / c mice bearing Meth-A fibrosarcoma and Colon 26 adenocarcinoma, the tumor accumulation of TES-23 was greater than that of the control IgG. In the present study, we report the anti-tumor effects of this monoclonal antibody in mice bearing Meth-A fibrosarcoma. Mice treated with the immunoconjugate showed improved survival with no side effects. This result indicates that common antigens may be found in different kinds of tumor endothelial cells, and that TES-23 might recognize these antigens.
Comparative verification into gait motion of healthy subjects and trans-femoral amputee based on singular value decomposition (2014)

In human gait locomotion analysis, which is one useful method for efficient physical rehabilitation to define various quantitative evaluation indices, ground reaction force, joint angle and joint loads are measured during gait. On the other hand, the analysis of the correlation in the recorded joint motion extracts a few simultaneously activating segmental coordination patterns, and the structure of the intersegmental coordination is attracting attention to an expected relationship with a control strategy. However, this procedure has not been applied to trans-femoral prosthetic gait locomotion yet. In this paper, joint angles as kinematic parameters applied on the lower limb of healthy subjects and trans-femoral amputee with the prosthetic limb during their gait locomotion are analyzed by singular value decomposition and mutual comparative verification of them is performed. As a result of the experiments and consideration, the effectiveness of the method using singular value decomposition is validated because it can quantitatively express comprehensive physical phenomena for trans-femoral prosthetic gait.
Nuclear magnetic resonance studies of the solution chemistry of metal complexes. 18. Complexation of palladium(II) by glycyl-L-histidine and glycyl-L-histidylglycine (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNuclear magnetic resonance studies of the solution chemistry of metal complexes. 18. Complexation of palladium(II) by glycyl-L-histidine and glycyl-L-histidylglycineDallas L. Rabenstein, Anvarhusein A. Isab, and Mohamed M. ShoukryCite this: Inorg. Chem. 1982, 21, 8, 3234–3236Publication Date (Print):August 1, 1982Publication History Published online1 May 2002Published inissue 1 August 1982https://pubs.acs.org/doi/10.1021/ic00138a061https://doi.org/10.1021/ic00138a061research-articleACS PublicationsRequest reuse permissionsArticle Views77Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Photochemical Reductive trans-Elimination from trans-Diacidotetracyanoplatinate(IV) Complexes (1978)

Abstract Upon CT excitation the complex ions trans-[Pt(CN) 4 N 3 X] 2- and trans-[Pt(CN) 4 X 2 ] 2- (X = Cl and Br) undergo a reductive trans-elimination with formation of [Pt(CN) 4 ] 2- and two ligand radicals in the photoprimary step. The formation of a Pt(III) intermediate is not observed. Due to the stability of [Pt(CN) 4 ] 2- , recombination reactions regenerating the starting complex are efficient if the ligand radicals are not scavenged. For the azide complexes the high quantum yields for the production of [Pt(CN) 4 ] 2- are explained by the instability of azide radicals. For trans-[Pt(CN) 4 X 2 ] 2- , the recombination is efficient in aqueous solution, while in ethanol the halogen atoms are scavenged by hydrogen abstraction. The sequence of steps following CT excitation can be explained by a potential energy diagram.
Tailored Preparation Methods of TiO2 Anatase, Rutile, Brookite: Mechanism of Formation and Electrochemical Properties (2009)

Using a simple aqueous precipitation method based on a low-cost titanium oxysulfate precursor, we have prepared three TiO2 polymorphs: anatase, rutile, and brookite. Although the anatase form can be directly obtained from the thermolysis reaction of an oxysulfate solution, the rutile and the brookite have been prepared by the addition of oxalate species. Depending on the concentration, the oxalate anions have been shown to act either as a ligand with the stabilization of a titanium oxalate hydrate, Ti2O3(H2O)2(C2O4)·H2O, or as a chelating agent with the isolation of the rutile phase. The brookite form was obtained by thermal decomposition of the oxalate hydrate at a temperature as low as 300 °C. The resulting solid consisted of nanodomains of TiO2 brookite embedded in large micrometer-size particles and exhibited a high specific surface area of 255 m2/g because of the mesoporosity arising from the removal of water from the oxalate species. This type of morphology is of interest for lithium-ion batteries because of an easier coating process and a higher surface contact between the material and the electrolyte that enhanced the electrochemical activity. Finally, based on electrochemical characterizations, TiO2 brookite provided higher volumetric energy density than comparable nanomaterials.
Dynamic Flow Reconfiguration Strategy to Avoid Communication Hot-Spots (2011)

Application-specific Network-on-Chip allows optimization for the interconnection to minimize its cost. When used with streaming applications, large flows of data can be predicted. However, these flows can be modified during the applications providing a dynamic flow graph. In that case, applying on off-line optimization leads to an over-sizing of the NoC. On the other hand, dynamic reconfiguration leads to unordered data deliveries with costly re-ordering units. In this paper, we propose a coarse grain dynamic reconfiguration which avoids data re-ordering requirement. We show that the proposed solution is efficient to deal with communication hot-spots, with a small area overhead, and can save up to 33% of latency.
Abstract B188: Inhibition of Notch signaling for the treatment of cancer (2009)

Abstract The Notch pathway is a highly conserved signaling system that plays an important role in development and tissue homeostasis. While Notch mutations are well characterized and implicated in hematological malignancies such as T-cell acute lymphoblastic leukemia, in solid tumors ligand or receptor over-expression may lead to enhanced/sustained Notch function, triggering increased tumor cell proliferation/survival, angiogenesis and tumor formation. In order to delineate an oncogenic role of activated Notch in tumors of epithelial origin, we carried out a series of in-vitro and in-vivo studies. We demonstrated that the activated Notch1 receptor (a - secretase-dependent Notch1 E with the transmembrane domain and a-secretase-independent constitutively activated Notch1 intracellular fragment) can transform normal rat cells, RK3E. These transformed cells formed colonies in soft agar, confirming their anchorage-independent growth potential, and when implanted subcutaneously, formed tumors in athymic nude mice. Inhibition of Notch signaling through a small molecule inhibitor of -secretase, a key regulator of Notch processing, may provide an attractive targeted cancer therapeutic strategy. We have identified and characterized a novel small molecule that is an exquisitely potent inhibitor of Notch signaling in tumor cell lines and endothelial cells with an IC50 ranging from 0.005 nM to 20 nM. The Notch inhibitor meets all pharmacokinetic criteria in pre-clinical species. In a xenograft tumor model, the novel compound inhibited Notch cleavage in a dose-dependent manner at 6 hours after a single oral dose. This inhibition of Notch cleavage resulted in the induction of apoptosis (as measured by activated caspase-3 levels) that was statistically significant at 24 hours after a single oral dose of 3 mg/kg. Analysis of tumors from animals treated with the Notch inhibitor revealed inhibition of angiogenesis through formation of leaky vasculature which may also contribute to observed anti-tumor activity. Furthermore, Notch inhibition produced tumor regression in the Notch-dependent tumor models. Anti-tumor activity was also observed in several human xenograft tumors of epithelial origin. To mitigate mucoid gasteroentropathy due to Notch inhibition, PK/PD data were incorporated in devising dosing strategies that identified an optimal intermittent dosing schedule without negatively impacting efficacy. Furthermore, the mucoid gastroentropathy was also mitigated by the prophylactic administration of dexamethasone without negatively impacting Notch inhibitor mediated efficacy. In summary, we have characterized an orally bio-available small molecule Notch inhibitor that may provide therapeutic benefit to cancer patients. Citation Information: Mol Cancer Ther 2009;8(12 Suppl):B188.