gebhart/patrepeval huggingface dataset:
Multiple bonds between transition metals and main group elements. 37. Naked lead in a trigonal-planar environment (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMultiple bonds between transition metals and main group elements. 37. Naked lead in a trigonal-planar environmentHeinz Josef Kneuper, Eberhardt Herdtweck, and Wolfgang A. HerrmannCite this: J. Am. Chem. Soc. 1987, 109, 8, 2508–2509Publication Date (Print):April 1, 1987Publication History Published online1 May 2002Published inissue 1 April 1987https://doi.org/10.1021/ja00242a043RIGHTS & PERMISSIONSArticle Views157Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (278 KB) Get e-Alerts Get e-Alerts
Harmonic Effects in Electrostatic Induction Motors (1985)

Abstract Electrostatic Induction motors are closely connected in theory to the familiar Tesla induction machine. In practice, designs are constrained by dielectric breakdown. Stator and rotor electrodes must be positioned to avoid breakdown rather than to provide sinusoidal distributions. The result is that Space and time harmonics are important in electrostatic machines. A cylindrical and in experimental electrostatic Induction motor is described. The electric field the air gap is used to compute theoretical torque, which is less than 4 mN · m under most conditions. Experimental operation with balanced three-phase excitation and bearing friction as the only load agrees with the theory more closely than in previous work.
The Optimal Dosing Regimen for Tranexamic Acid in Revision Total Hip Arthroplasty (2020)

Therapeutic Level I. See Instructions for Authors for a complete description of levels of evidence.
IVF and retinoblastoma (2005)

I read with great interest the letter published in the BJO by Lee et al .1 It reports on the first child born after in vitro fertilisation (IVF) and harbouring a unilateral retinoblastoma in the United States.

However, it should be noted that this reported child is the eighth documented child (not the sixth as mentioned by the authors). The first child ever observed was reported by our group …
Anti-idiotypic Antibodies Against Anti-CD4 Antibodies MT151 and OKT4A (1991)

Anti-idiotypic antibodies (Ab2) binding to the antigen-combining site of other antibodies may functionally and even structurally mimic antigen. Ab2 to antibodies directed against the lymphocyte CD4 receptor for human immunodeficiency virus type 1 (HIV-1) may mimic the receptor and therefore inhibit viral infectivity. We have produced Ab2 against monoclonal anti-CD4 receptor antibodies (Ab1). The Ab1 strongly inhibit HIV-1 binding to the receptor. Six monoclonal rat Ab2 and two polyclonal rabbit Ab2 were produced against the Ab1 MT151 and nine monoclonal Ab2 against the Ab1 OKT4A. These Ab2 bound only to Ab1 and not to a panel of nine unrelated murine monoclonal antibodies (MAbs). The Ab2 completely inhibited the binding of the homologous Ab1 to CD4-positive target cells, and recombinant soluble CD4 inhibited binding of Ab2 to Ab1. Thus, the Ab2 seemed to mimic the Ab1-binding site of the CD4 receptor, although the results of inhibition assays did not exclude steric hindrance of antibody-combining sites. However, none of the 17 Ab2 bound to gp120 of HIV-1 envelope or inhibited syncytia formation between cells infected and uninfected with HIV-1. These results suggest that the Ab2 do not mimic the HIV-1 binding site of the CD4 receptor. They further suggest that the Ab1 may not bind within the virus-binding site of the CD4 receptor.
ChemInform Abstract: A New Microporous Polymorph of Silica Isomorphous to Zeolite MCM‐22. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The molecular structures of some cyclopentadienyl nitrosyl complexes (1969)

M. A. Bush, G. A. Sim, G. R. Knox, M. Ahmad and C. G. Robertson, J. Chem. Soc. D, 1969, 74 DOI: 10.1039/C29690000074
Pharmaceutical Process Chemistry for Synthesis: Rethinking the Routes to Scale-Up (2011)

1 Introduction. 2 Actos(R) (Pioglitazone Hydrochloride). 3 Lexapro(R) (Escitalopram Oxalate). 4 Efferox XR(R) (Venlafaxine Hydrochloride). 5 Seroquel(R) (Quetiapine Hemifumarate). 6 Singulair(R) (Montelukast Sodium). 7 Prevacid(R) (Lansoprazole). 8 Advair Diskus(R) (Salmeterol Xinafoate). 9 Lipitor(R) (Aatorvastatin Calcium). Index.
Neurotrophins enhance retinal pigment epithelial cell survival through neuroprotectin D1 signaling (2007)

Integrity of retinal pigment epithelial cells is necessary for photoreceptor survival and vision. The essential omega-3 fatty acid, docosahexaenoic acid, attains its highest concentration in the human body in photoreceptors and is assumed to be a target for lipid peroxidation during cell damage. We have previously shown, in contrast, that docosahexaenoic acid is also the precursor of neuroprotectin D1 (NPD1), which now we demonstrate, acts against apoptosis mediated by A2E, a byproduct of phototransduction that becomes toxic when it accumulates in aging retinal pigment epithelial (RPE) cells and in some inherited retinal degenerations. Furthermore, we show that neurotrophins, particularly pigment epithelium-derived factor, induce NPD1 synthesis and its polarized apical secretion. Moreover, docosahexaenoic acid (DHA) elicits a concentration-dependent and selective potentiation of pigment epithelial-derived factor-stimulated NPD1 synthesis and release through the apical RPE cell surface. The bioactivity of signaling activated by pigment epithelium-derived factor and DHA uncovered synergistic cytoprotection with concomitant NPD1 synthesis when cells were challenged with oxidative stress. Also, DHA and pigment epithelium-derived factor synergistically modify the expression of Bcl-2 family members, activating antiapoptotic proteins and decreasing proapoptotic proteins, and by attenuating caspase 3 activation during oxidative stress. Thus, our findings demonstrate that DHA-derived NPD1 protects against RPE cell damage mediated by aging/disease-induced A2E accumulation. Also, our results identify neurotrophins as regulators of NPD1 and of its polarized apical efflux from RPE cells. Taken together, these findings imply NPD1 may elicit autocrine actions on RPE cells and paracrine bioactivity in cells located in the proximity of the interphotoreceptor matrix.
Low-overhead Aging-aware Resource Management on Embedded GPUs (2017)

GPUs have been employed in the embedded systems to handle increased amount of computation and satisfy the timing requirement. Therefore, the lifetime of embedded GPUs is considered one of the most important aspects to ensure functional correctness over a long period of time. Moreover, existing state-of-the-art compiler-based GPU aging management techniques suffer from a considerable amount of performance overhead. In this paper, we propose a low-overhead aging-aware resource management technique. The proposed technique extends the behavior of the existing warp scheduler and the instruction dispatcher to cluster the computational cores and distribute instructions based on the aging information. Compared to when using the original applications, our technique improves the aging of the embedded GPU by 30% on average. In addition, compared to the state-of-the-art GPU aging management technique, our technique reduces the performance overhead by 16.4% on average while improving the aging by 3% on average.
Average transition density constraints for mitigating transition noise in magnetic recording (2004)

To mitigate transition noise in magnetic recording is to reduce the number of transitions that are written onto the media. This leads one to consider an average transition density (ATD) constraint. This new constraint reduces the ATD of sequences at the channel input and can be imposed in addition to other constraints. In this paper ATD constraint is imposed which is based on assigning a particular cost function to a finite-state transition diagram (FSTD) that presents a constrained system of binary NRZI sequences. At a normalized linear user density the performance of an unconstrained system satisfying an ATD constraint was simulated using a microtrack longitudinal (Lorentzian) recording model corrupted by transition noise and electronics noise.
Novel Pt-Ni Electrocatalyst for Coal Electrolysis for Hydrogen Production (2022)

Carbon fiber-supported Pi-Ni binary alloy electrocatalyst (Pi-Ni/CFs) with different nickel contents is synthesized using impregnation-hydrogen reduction method for coal electrolysis to produce hydrogen. The electrode based on the Pt-Ni/CFs is characterized using X-ray diffraction (XRD), scanning electron microscope (SEM) with energy-dispersive X-ray analysis (EDS) and X-ray photoelectron spectroscopy (XPS) and transmission electron microscopy (TEM). The results indicate Pt-Ni alloy formed on the CFs. Electrochemical results show that Pt-Ni/CFs have higher electrocatalytic activity than pure Pt/CFs, with Pt-Ni/CFs (1:1) electrode exhibiting the best performance. Compared with the pure Pt/CFs, the efficiency of coal electrolysis for hydrogen production is increased by 13.8% with Pt-Ni/CFs (1:1). The improved performance of Pt-Ni/CFs is attributed to the modification of surface electronic properties due to metallic alloying.
Identification of DNA methylation markers for early detection of CRC indicates a role for nervous system-related genes in CRC (2021)

In silico discovery analysis using TCGA-derived data yielded a novel DNA-methylation-based assay for the early detection of CRC, potentially improving current screening modalities. Additionally, nervous system-related pathways were enriched in the identified genes, indicating an epigenetic regulation of neuronal genes in CRC.
Short- and long-term haemodynamic consequences of transcatheter closure of atrial septal defect and patent foramen ovale (2021)

Older patients and patients with AF were predisposed to sustained increases in left-sided filling pressures resembling HFpEF following ASD or PFO closure. Consequently, these findings support the current concept that creating a restricted interatrial shunt might be beneficial, particularly in elderly HFpEF patients with AF.
Structures of a Clathrate Hydrate Former, Inhibitor, and Synergist in Water (2018)

SANS studies are reported for aqueous THF at the 1:17 clathrate hydrate-forming composition and on aqueous solutions of the synergist 2-butoxyethanol. Addition of the clathrate hydrate inhibitor polyvinylcaprolactam and a dimeric model compound, 1,3-bis(caprolactamyl)butane, show that the inhibitors do not significantly affect the solution structures of these two important species in clathrate hydrate formation and inhibition. The SANS studies show that 1,3-bis(caprolactamyl)butane is a good model for polyvinylcaprolactam, and both the polymer and model compound exhibit hydrogen bonding interactions with water but do not interact significantly with 2-butoxyethanol in aqueous solution.
Inflammatory Gene Profiling in the Developing Mouse Brain after Hypoxia-Ischemia (2004)

Brain ischemia triggers an inflammatory reaction that progresses for days to weeks and seems to have a role in secondary progression of injury. Inflammation induces a complex pattern of signaling molecules with partly contradictory actions, and the responses may be different in the immature and adult brain. The authors characterized the global inflammatory gene expression in the developing brain as a first step toward understanding the protective and deleterious effects of inflammation after hypoxia-ischemia. Oligonucleotide arrays were used to investigate inflammatory genes in cortex, hippocampus, thalamus, and striatum at 2, 8, 24, and 72 hours after hypoxia-ischemia, which was induced in 9-day-old mice by left carotid artery ligation followed by hypoxia. After hypoxia-ischemia, 148 inflammatory genes were differentially expressed. More than 97% of the genes were upregulated and 93% had not previously been reported after hypoxia-ischemia in the immature brain. The results indicate that microglia/macrophages, T- and B-cells, NK-cells, mast cells, dendritic cells, and polymorphonuclear leukocytes may participate in the response to hypoxia-ischemia. In addition, novel cytokines/chemokines, complement-related, interferon-regulated, components of the TIR/nuclear factor-kappaB pathway, and a number of immunomodulatory genes were induced. Several of these genes may of pathophysiologic significance after neonatal hypoxia-ischemia.
The miniature optical transmitter and transceiver for the High-Luminosity LHC (HL-LHC) experiments (2013)

We present the design and test results of the Miniature optical Transmitter (MTx) and Transceiver (MTRx) for the high luminosity LHC (HL-LHC) experiments. MTx and MTRx are Transmitter Optical Subassembly (TOSA) and Receiver Optical Subassembly (ROSA) based. There are two major developments: the Vertical Cavity Surface Emitting Laser (VCSEL) driver ASIC LOCld and the mechanical latch that provides the connection to fibers. In this paper, we concentrate on the justification of this work, the design of the latch and the test results of these two modules with a Commercial Off-The-Shelf (COTS) VCSEL driver.
Micro-optical lenslets by photo-expansion in chalcogenide glasses (1997)

A detailed study of the wavelength dependence of the formation of lenslets by photo-expansion in chalcogenide glasses is reported. Photo-expansion in chalcogenide glasses offers a one-step fabrication process to record surface structures such as gratings and microlenses. The process is purely optical and requires no fixing and etching to get the desired surface structure. Two competing effects, namely large volumes accessed by low energy photons and large magnitudes of photostructural changes due to high energy photons, provide the possibility of using different fabrication techniques to obtain lenslets by the photo-expansion process. Strongly absorbed 514.5 nm light is used to record micro-optical lenslets in As/sub 2/S/sub 3/ glass and up to 10% relative volume changes are observed. The low power density requirements at this wavelength are used to demonstrate a parallel lithographic fabrication technique for recording lenslets with high repeatability and throughput, and with excellent control over curvature and dimensions. The magnitude of surface dilation is maximized at the photon energy that combines the advantage of short wavelength exposures in producing large percentage volume changes, with the advantage of low energy photons in irradiating large volumes of the glass matrix. A variety of wavelengths within the Urbach tail range of the optical absorption edge are employed to find the optimal wavelength for large absolute volume changes in As/sub 2/S/sub 3/ glass. Lenslets as high as 8 /spl mu/m are fabricated with focused light exposures from a dye laser operating at 584.5 nm. Lenslets are structurally characterized with alpha-step scanners and an atomic force microscope (AFM) and are optically characterized by testing the collimation of 1550-nm light emerging from a single-mode fiber with these lenslets.
Post-processing optimization of piecewise indoor trajectories based on IMU and RSS measurements (2017)

Post-processing indoor navigation is interesting, for example to develop crowdsourcing analysis. The post-processing framework allows to provide a better estimation than in a real-time framework. The main contribution of this paper is to present a piecewise parametrization using Inertial Measurement Unit (IMU) and Received Signal Strength (RSS) measurements only which lead to an optimization problem. A Levenberg-Marquardt algorithm improved with simulated annealing and an adjustment of RSS measurements data leads to a good estimation (55% of the error less than 5 meters) of the trajectory.
Distributed Waveform Generator: A New Circuit Technique for Ultra-Wideband Pulse Generation, Shaping and Modulation (2009)

A new circuit technique, the distributed waveform generator (DWG), is proposed for low-power ultra-wideband pulse generation, shaping and modulation. It time-interleaves multiple impulse generators, and uses distributed circuit techniques to combine generated wideband impulses. Built-in pulse shaping can be realized by programming the delay and amplitude of each impulse similar to an FIR filter. Pulse modulation schemes such as on-off keying (OOK) and pulse position modulation (PPM) can be easily applied in this architecture. Two DWG circuit prototypes were implemented in a standard 0.18 mum digital CMOS technology to demonstrate its advantages. A 10-tap, 10 GSample/s, single-polarity DWG prototype achieves a pulse rate of 1 GHz while consuming 50 mW, and demonstrates OOK modulation using 16 Mb/s PRBS data. A 10-tap, 10 GSample/s, dual-polarity DWG prototype was developed to generate UWB pulses compliant with the transmit power emission mask. Based on the latter DWG design, a reconfigurable impulse radio UWB (IR-UWB) transmitter prototype was implemented. The transmitter's pulse rate can be varied from 16 MHz range up to 2.5 GHz. The bandwidth of generated UWB pulses is also variable, and was measured up to 6 GHz (- 10 dB bandwidth). Both OOK and PPM modulation schemes are successfully demonstrated using 32 Mb/s PRBS data. The IR-UWB transmitter achieves a measured energy efficiency of 45 pJ/pulse, independent of pulse rate.
Impact of dose and duration of corticosteroid on the risk of hepatitis flare in patients with chronic hepatitis B (2018)

Even short courses of high-dose corticosteroid increase the risk of hepatitis flare in CHB patients. Patients receiving high-dose corticosteroid should be considered for antiviral prophylaxis regardless of the duration of treatment.
Analysis of coulomb stress changes during 1997-1998 intrusive period at Mt. Etna volcano (2009)

(3) Istituto Nazionale di Geofisica e Vulcanologia, Sezione di Catania, Catania, Italy (palano@ct.ingv.it, +39 95 435801), (1) Universita degli Studi di Catania, Dipartimento di Elettronica e dei Sistemi, Viale Andrea Doria 6, 95125, (2) Universita degli Studi di Catania, Dipartimento di Geologia e Geofisica, Corso Italia 57, 95129 Catania, Italy, (4) Dept. Physics of the Earth, GFZ German Research Centre for Geosciences, Germany
Photorefractive deflection technique using parallel and overlaping probe and pump beams (1986)

The present work provides an experimental study of a pulsed photorefractive technique to diagnose the interior of an irradiated region. Results obtained in a mixture of SF 6 and Ar are presented to illustrate the experimental technique. Three distinct areas have been studied, (i) The two beams are parallel and their optical axes are coincident (collinear). At this particular position, the probe beam suffers a defocusing effect that is used to align collinearly two laser beams with a precision of ±3 μm. (ii) The two beams are parallel but slightly off axis. In this case, the probe beam suffers a deviation that is the sole result of a rarefaction in the irradiated region followed by the normal thermal equilibration. (iii) The two beams are parallel and slightly overlapping. The probe beam suffers a deviation similar to the preceding one. Moreover, it sees an initial outward-propagating acoustic (density) wave. It is in this particular region that the acoustic perturbation appears. Finaly, the gas mixture used under our experimental conditions is a good candidate for the collinear alignment of several laser beams. The only restrictions are that the pump laser must produce a beam with a symmetrical intensity profile, the other laser beams must be continuous-wave beams, and the gas mixture must be transparent to the latter.
Fabrication of GaN Nanorods in a Large Scale on Si(111) Substrate by Ammoniating Technique (2006)

GaN nanorods in a large scale have been synthesized on Si (111) substrates by ammoniating Ga2O3/Mg films under flowing ammonia atmosphere at the temperature of 1000°C for 15 min. The as-synthesized GaN nanorods are characterized by scanning electron microscopy, x-ray diffraction, x-ray photoelectron spectroscopy, and high-resolution transmission electron microscopy. The results demonstrate that these straight nanorods are hexagonal wurtzite GaN single crystals in diameters ranging from 200 nm to 600 nm.
A validated 3D microstructure-based constitutive model of coronary artery adventitia (2016)

A structure-based model that accurately predicts micro- or macromechanical behavior of blood vessels is necessary to understand vascular physiology. Based on recently measured microstructural data, we propose a three-dimensional microstructural model of coronary adventitia that incorporates the elastin and collagen distributions throughout the wall. The role of ground substance was found to be negligible under physiological axial stretch λz = 1.3, based on enzyme degradation of glycosaminoglycans in swine coronary adventitia (n = 5). The thick collagen bundles of outer adventitia (n = 4) were found to be undulated and unengaged at physiological loads, whereas the inner adventitia consisted of multiple sublayers of entangled fibers that bear the majority of load at higher pressures. The microstructural model was validated against biaxial (inflation and extension) experiments of coronary adventitia (n = 5). The model accurately predicted the nonlinear responses of the adventitia, even at high axial force (axial stretch ratio λz = 1.5). The model also enabled a reliable estimation of material parameters of individual fibers that were physically reasonable. A sensitivity analysis was performed to assess the effect of using mean values of the distributions for fiber orientation and waviness as opposed to the full distributions. The simplified mean analysis affects the fiber stress-strain relation, resulting in incorrect estimation of mechanical parameters, which underscores the need for measurements of fiber distribution for a rigorous analysis of fiber mechanics. The validated structure-based model of coronary adventitia provides a deeper understanding of vascular mechanics in health and can be extended to disease conditions.
Human pre‐α‐trypsin inhibitor‐precursor heavy chain cDNA and deduced amino‐acid sequence (1993)

Pre-alpha-trypsin inhibitor (P alpha I) is a serine-proteinase inhibitor of M(r) 130,000 found in human serum. This protein belongs to the family of proteins called inter-alpha-trypsin inhibitor (ITI). P alpha I is composed of a heavy chain (HC3) and of a light chain (bikunin), synthesized by two separate mRNA. Bikunin is identical to the ITI light chain, the structure of which has already been established. The HC3 is obtained from a precursor called H3. The bikunin is covalently linked to HC3 by a chondroitin-4-sulfate glycosaminoglycan. We report here the H3 full-length cDNA sequence and the deduced amino-acid sequence of the heavy-chain H3 precursor. The high degree of similarity between the nucleotide and amino-acid sequences of ITI heavy-chain families H1, H2, H3 is examined with respect to their probable structure and assembly with bikunin in the final proteins, P alpha I and ITI.