gebhart/patrepeval huggingface dataset:
ABH incompatible bone marrow transplantation: removal of erythrocytes by starch sedimentation (1983)

Nineteen patients with acute leukaemia underwent bone marrow transplantation despite major ABH incompatibility between donor and recipient. The marrow inoculum was prepared prior to infusion by admixture with hydroxyethyl starch to sediment the incompatible erythrocytes, which were then discarded. The infusion was well tolerated with two patients developing transient haemoglobinuria, seven patients developing low grade fever and 10 experiencing no reaction. Durable haematopoietic engraftment was achieved in the 18 evaluable patients and was not influenced by pre-transplant isohaemagglutinin titres. No difference in time to engraftment, incidence of GVHD or in overall survival was found, compared to ABH compatible transplants. Therefore, the presence of incompatibility did not appear to influence transplant outcome adversely. The technique described is a rapid and safe method for overcoming the ABH barrier in marrow transplantation.
The Available and Required Autoignition Quality of Gasoline - Like Fuels in HCCI Engines at High Temperatures (2004)

&lt;div class="htmlview paragraph"&gt;In previous work it has been shown that the autoignition quality of a fuel at a given operating condition can be described by its Octane Index, OI = (1-K)RON - KMON; the larger the OI, the more the resistance to autoignition. Here RON and MON are, respectively, the Research and Motor Octane numbers of the fuel and K is a constant depending only on the pressure and temperature history of the fuel / air mixture in the engine prior to autoignition. The value of K is empirically established at a given operating condition by ranking fuels of different RON and MON and of different chemical composition for their ease of autoignition. Another important parameter at a given operating condition is OI&lt;sub&gt;0&lt;/sub&gt;, the Octane Index of the fuel for which heat release is centred at TDC. In previous work K and OI&lt;sub&gt;0&lt;/sub&gt; were measured at different operating conditions and were related empirically to pressure and temperature of the mixture before autoignition and to engine speed and mixture strength.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;In this work K and OI&lt;sub&gt;0&lt;/sub&gt; have been measured in a different engine at different conditions that include much higher intake temperatures and engine speeds than considered before. The focus is also on wide-boiling-range complex fuels rather than simple fuel systems. K is again seen to depend primarily on the compression temperature at 15 bar, T&lt;sub&gt;comp15&lt;/sub&gt;. However in the higher temperature range, K increases much more sharply with T&lt;sub&gt;comp15&lt;/sub&gt; than found previously. There is also an overlap between the new data and the old data, confirming that the variation of K is not engine dependent. The data for OI&lt;sub&gt;0&lt;/sub&gt; for the two engines can also be described by a combined model. OI&lt;sub&gt;0&lt;/sub&gt; increases with increasing P&lt;sub&gt;maxcomp&lt;/sub&gt; and T&lt;sub&gt;maxcomp&lt;/sub&gt;, the compression pressure and temperature at TDC, and decreases with increasing λ and engine speed.&lt;/div&gt;
Comparison of putative cGMP-binding regions in bovine brain and cardiac cGMP-stimulated phosphodiesterases. (1991)

After photolabelling of purified bovine brain particulate cGMP stimulated phosphodiesterase (PDE) with [32P]cGMP, incubation with V8 Endoproteinase Glu-C produced several fragments; most of the [32P] was associated with smaller fragments (approximately 12-14 kDa), and some occasionally with larger fragments (approximately 55-57 kDa). Partial amino acid sequences were determined for the smaller photolabelled fragments and other peptides. On Western immunoblots, affinity-purified antibodies against a synthetic peptide with a sequence matching part of that of the approximately 12-14 kDa photolabelled material reacted with intact PDE and the approximately 12-14 kDa and approximately 55-57 kDa fragments. Several partial cDNA clones encoding the cGMP-stimulated PDE were isolated from a Lambda Zap II bovine brain cDNA library. Deduced amino acid sequence from one cDNA clone, lambda cGS 3-1, as well as the partial sequence of the approximately 12-14 kDa and other fragments, exhibited considerable identity with amino acid residues 311-921 of the cardiac cGMP-stimulated PDE (Trong et al., 1990), including the putative cGMP-binding domain (Charbonneau et al., 1990). These results further define this cGMP-binding domain and suggest that different cGMP-stimulated PDEs will exhibit considerable homology, at least in their cGMP-binding region(s) and catalytic domains.
Automatically Extracting Dialog Models from Conversation Transcripts (2009)

There is a growing need for task-oriented natural language dialog systems that can interact with a user to accomplish a given objective. Recent work on building task-oriented dialog systems have emphasized the need for acquiring task-specific knowledge from un-annotated conversational data. In our work we acquire task-specific knowledge by defining sub-task as the key unit of a task-oriented conversation. We propose an unsupervised, apriori like algorithm that extracts the sub-tasks and their valid orderings from un-annotated human-human conversations. Modeling dialogues as a combination of sub-tasks and their valid orderings easily captures the variability in conversations. It also provides us the ability to map our dialogue model to AIML constructs and therefore use off-the-shelf AIML interpreters to build task-oriented chat-bots. We conduct experiments on real world data sets to establish the effectiveness of the sub-task extraction process. We codify the extracted sub-tasks in an AIML knowledge base and build a chatbot using this knowledge base. We also show the usefulness of the chatbot in automatically handling customer requests by performing a user evaluation study.
Role of placenta growth factor in malignancy and evidence that an antagonistic PlGF/Flt-1 peptide inhibits the growth and metastasis of human breast cancer xenografts (2007)

The angiogenic growth factor placenta growth factor (PlGF) is implicated in several pathologic processes, including the growth and spread of cancer. We found by immunohistochemistry that 36% to 60% and 65% of primary breast cancers express PlGF and its receptor Flt-1, respectively. These findings suggest that PlGF may be active in tumor growth and metastasis beyond its role in angiogenesis. It was found that exogenously added PlGF (2 nmol/L), in contrast to vascular endothelial growth factor (2 nmol/L), significantly stimulated in vitro motility and invasion of the human breast tumor lines MCF-7 and MDA-MB-231. A PlGF-2/Flt-1-inhibiting peptide, binding peptide 1 (BP1), that binds Flt-1 at or near the heparin-binding site was identified and synthesized. Both PlGF-stimulated motility and invasion were prevented by treatment with BP1 (P < 0.05), as well as by anti-PlGF antibody. Treatment of mice bearing s.c. MDA-MB-231 with BP1 (200 mug i.p., twice per week) decreased the number of spontaneous metastatic lung nodules by 94% (P < 0.02), whereas therapy of animals with orthotopic mammary fat pad tumors decreased pulmonary metastases by 82% (P < 0.02). These results indicate, for the first time, that PlGF stimulates the metastatic phenotype in these breast cancer cells, whereas therapy with a PlGF-2/Flt-1 heparin-blocking peptide reduces the growth and metastasis of human breast cancer xenografts.
Primary Total Hip Arthroplasty (1996)

The best method of fixation between the implant and host bone in total hip arthroplasty (THA) remains controversial. Many factors such as patient activity level and bone quality are important in determining the method that best meets the individual patient's needs. This review examines the historical reasoning behind these methods of fixation and reviews several clinical studies that evaluate long-term care outcomes of THA with respect to implant fixation.
ChemInform Abstract: Ionic Liquid Processing of Cellulose (2012)

Abstract Review: 142 refs.
Survey of rodent-borne pathogens in Singapore reveals the circulation of Leptospira spp., Seoul hantavirus, and Rickettsia typhi (2022)

Rodents living alongside humans increases the probability of encounter and also the transmission of rodent-borne diseases. Singapore's cosmopolitan urban landscape provides a perfect setting to study the prevalence of four rodent-borne pathogens: Seoul hantavirus (SEOV), Leptospira species, Rickettsia typhi and Yersinia pestis, and identify the potential risk factors which may influence rodent density and transmission of rodent-borne diseases. A total of 1143 rodents were trapped from 10 unique landscape structures throughout Singapore. Real-time quantitative Polymerase Chain Reactions were used to detect pathogenic and intermediate Leptospira spp. and Yersinia pestis, whereas the seroprevalence of SEOV and R. typhi were analysed by Enzyme-Linked Immunosorbent Assay and Immunofluorescence Assay respectively. Multivariable logistic regression analysis was used to evaluate the association between prevalence of infection in rodent reservoirs and risk factors. Most of the rodents were caught in public residential developments (62.2%). Among the tested rodents, 42.4% were infected with Leptospira spp., while 35.5% and 32.2% were seropositive for SEOV and R. typhi respectively, whereas Yersinia pestis was not detected. Furthermore, risk factors including habitat, species, gender, and weight of rodents, influenced prevalence of infection to a varying extent. This study highlights the presence of Leptospira spp., SEOV and R. typhi in Singapore's rodent population, suggesting the need for effective rodent management and sanitation strategies to prevent further circulation and transmission to humans.
PdNPs@ZIF‐8 Micro‐Nanostructured Catalyst of Regioselective Mizoriki‐Heck Olefination (2017)

Abstract ZIF‐8‐supported Pd nanoparticles (PdNPs) have been synthesized as a heterogeneous catalyst (PdNPs@ZIF‐8) for the Mizoriki‐Heck C−C bond formation reaction. The hexagonal ZIF‐8 microcrystals were converted to rod‐ and flower‐shaped PdNPs@ZIF‐8 with the controlled addition of formic acid. PdNPs@ZIF‐8 was applied to catalyze the coupling of arylhalides with substituted styrenes, achieving excellent conversion with very high selectivity.
Protective effect of extract of chicken meat on restraint stress-induced liver damage in mice (2012)

In this study, we investigated the protective effects of the extract of chicken meat (EC) on liver damage in mice caused by restraint stress. Our results showed that 18 h of restraint stress-induced liver damage was marked by an increase of plasma alanine aminotransferase (ALT) and aspartate aminotransferase(AST) levels. However, oral administration of EC (0.12 and 0.24 mL/10 g per day, 7 d) was found to reduce the increased plasma ALT and AST levels in stressed mice. Meanwhile, EC significantly decreased the contents of malondialdehyde and increased the activities of superoxide dismutase (SOD) and glutathione peroxidase (GPX) in plasma or liver of stressed mice. The gene expressions of antioxidative enzymes (Cu/Zn-SOD, Mn-SOD and GPX) were also up-regulated in the EC-treated group when compared with the stressed group. In addition, EC administration was found to resist a stress-induced increase of plasma corticosterone levels and down-regulation of liver glucocorticoid receptor gene expression. These results suggested that EC could protect against restraint stress-induced liver damage by smoothing stress and promoting antioxidative processes.
Study of a flat-surface, high-pressure, pool boiling test instrument (2023)

A study has been conducted of a newly developed high-pressure instrument, capable of pool boiling testing on multiple flat surfaces without instrumentation of each sample tested. The instrument has a unique design for testing flat samples with instrumentation only in the instrument and a data reduction procedure appropriate for the design. The validity of the instrument design and data reduction procedure was verified through boiling water heat transfer testing on a flat stainless-steel surface at atmospheric and 0.69-MPa pressures. The boiling heat transfer results obtained were shown to be in reasonable agreement with predicted values from correlations in the engineering literature. This test instrument is especially useful for evaluating the performance of newly engineered surfaces, such as textured and coated surfaces, compared to that of the base surface, where experimental testing on the base and engineered surfaces under the same operation conditions is required, and instrumentation of the surfaces would be detrimental to them.
Real-Time Millimeter-Wave MIMO Channel Sounder for Dynamic Directional\n Measurements (2018)

In this paper, we present a novel real-time multiple-input-multiple-output\n(MIMO) channel sounder for the 28 GHz band. Until now, most investigations of\nthe directional characteristics of millimeter-wave channels have used\nmechanically rotating horn antennas. In contrast, the sounder presented here is\ncapable of performing horizontal and vertical beam steering with the help of\nphased arrays. Due to its fast beam-switching capability, the proposed sounder\ncan perform measurements that are directionally resolved both at the\ntransmitter(TX) and receiver (RX) in 1.44 milliseconds compared to the minutes\nor even hours required for rotating horn antenna sounders. This not only\nenables measurement of more TX-RX locations for a better statistical validity\nbut also allows to perform directional analysis in dynamic environments. The\nshort measurement time combined with the high phase stability limits the phase\ndrift between TX and RX, enabling phase-coherent sounding of all beam pairs\neven when TX and RX have no cabled connection for synchronization without any\ndelay ambiguity. Furthermore, the phase stability over time enables complex RX\nwaveform averaging to improve the signal to noise ratio during high path loss\nmeasurements. The paper discusses both the system design as well as the\nmeasurements performed for verification of the sounder performance.\nFurthermore, we present sample results from double directional measurements in\ndynamic environments.\n
Ein laseroptisches Gerät zur Bestimmung der Größenverteilungen von Wolken- und Nieseltropfen (1998)

The Malvern Particle Sizer (MPS), a laser-optical device, was used for measuring cloud, drizzle and raindrops. In this paper it is shown that the instrument is suitable for investigations on cloud and drizzle droplet size distributions due to the need of high number concentrations in the measuring volume. Furthermore it is shown that with only two instruments (MPS and Joss-Waldvogel-disdrometer) the whole drop size range from small cloud drops up to large raindrops is detectable. During the field campaign FELDEX 95 at Kleiner Feldberg drop distributions were measured, both with the MPS and with a disdrometer. Two periods were investigated. Differences in the development of the cloud drop size spectra were observed, and could be attributed to totally different raindrop spectra. In one case broader cloud drop spectra led to rather narrow drizzle spectra with large concentrations of small raindrops, typical for warm rain formation. These spectra differ completely from the corresponding Marshall-Palmer (MP)-distributions. In the other case narrow cloud drop spectra were associated with broad raindrop spectra which were in good agreement with Marshall-Palmer-distributions. Differences in the rain formation processes can explain these observations. At the end some improvements of the MPS-system are discussed which would be helpful for future work to overcome problems that occurred during the field measurements.
ChemInform Abstract: Direct Preparation of Diacetals from 1,2‐Diketones and Their Use as 1, 2‐Diol Protecting Groups. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
DD-CISENet: Dual-Domain Cross-Iteration Squeeze and Excitation Network for Accelerated MRI Reconstruction (2023)

Magnetic resonance imaging (MRI) is widely employed for diagnostic tests in neurology. However, the utility of MRI is largely limited by its long acquisition time. Acquiring fewer k-space data in a sparse manner is a potential solution to reducing the acquisition time, but it can lead to severe aliasing reconstruction artifacts. In this paper, we present a novel Dual-Domain Cross-Iteration Squeeze and Excitation Network (DD-CISENet) for accelerated sparse MRI reconstruction. The information of k-spaces and MRI images can be iteratively fused and maintained using the Cross-Iteration Residual connection (CIR) structures. This study included 720 multi-coil brain MRI cases adopted from the open-source fastMRI Dataset. Results showed that the average reconstruction error by DD-CISENet was 2.28 $\pm$ 0.57%, which outperformed existing deep learning methods including image-domain prediction (6.03 $\pm$ 1.31, p &lt; 0.001), k-space synthesis (6.12 $\pm$ 1.66, p &lt; 0.001), and dual-domain feature fusion approaches (4.05 $\pm$ 0.88, p &lt; 0.001).
Pervaporative Separation of Aromatic/Aliphatic Mixtures with Poly(Siloxane-co-Imide) and Poly(Ether-co-Imide) Membranes (2012)

Aromatic random copolyimides were synthesized and tested as membrane materials for the separation of a mixture of aromatic and aliphatic hydrocarbons by pervaporation. The polymers were synthesized by a two-step polycondensation route with a total of 4 aromatic dianhydrides, 4 aromatic diamines, and 3 diamino-terminated aliphatic oligomers containing either ether or siloxane units. Pervaporation experiments were conducted at two temperatures with toluene/n-heptane and benzene/n-heptane mixtures as feed streams. All polymers were selective toward the aromatic hydrocarbon. Introduction of siloxane units in the polymer generally led to very high hydrocarbon permeability coefficients, but caused a reduction in selectivity relative to that of the aromatic homopolyimide. Incorporation of ether units, on the other hand, did not generally cause such large increases in permeability, nor large decreases in selectivity. The performance of these materials was compared with previous results reported in the literature for other polymers.
Erratum: Kim, K.-P.; Singh, A.K.; Bai, X.; Leprun, L.; Bhunia, A.K. Novel PCR Assays Complement Laser Biosensor-Based Method and Facilitate Listeria Species Detection from Food. Sensors 2015, 15, 22672–22691 (2017)

The authors wish to correct the oligonucleotide sequence of primer E-LAP-F1 and LIS-R1 in Table 1in their paper published in Sensors [1], doi:10.3390/s150922672, http://www.mdpi.com/1424-8220/15/9/22672. The following table should be used.[...].
Predictor Antenna: A Technique to Boost the Performance of Moving Relays (2020)

In future wireless systems, a large number of users may access the networks via moving relays (MRs) installed on top of vehicles. One of the main challenges of MRs is rapid channel variation which may make channel estimation, and its following procedures, difficult. To address these issues, various schemes are designed, among which predictor antenna (PA) is a candidate. The PA setup refers to a system with two (sets of) antennas on top of a vehicle, where the PA(s) positioned in front of the vehicle is(are) utilized to predict the channel state information required for data transmission to the receive antennas (RAs) aligned behind the PA. In this paper, we introduce the concept and the potentials of PA systems. Moreover, summarizing the field trials for PAs and the 3GPP attempts on (moving) relays, we compare the performance of different PA and non-PA methods for vehicle communications in both urban and rural areas with the PA setup backhauled through terrestrial or satellite technology, respectively. As we show, with typical parameter settings and vehicle speeds, a single-antenna PA-assisted setup can boost the backhaul throughput of MRs, compared to state-of-the-art open-loop schemes, by up to 50%.
Learning a Partitioning Advisor with Deep Reinforcement Learning (2019)

Commercial data analytics products such as Microsoft Azure SQL Data Warehouse or Amazon Redshift provide ready-to-use scale-out database solutions for OLAP-style workloads in the cloud. While the provisioning of a database cluster is usually fully automated by cloud providers, customers typically still have to make important design decisions which were traditionally made by the database administrator such as selecting the partitioning schemes. In this paper we introduce a learned partitioning advisor for analytical OLAP-style workloads based on Deep Reinforcement Learning (DRL). The main idea is that a DRL agent learns its decisions based on experience by monitoring the rewards for different workloads and partitioning schemes. We evaluate our learned partitioning advisor in an experimental evaluation with different databases schemata and workloads of varying complexity. In the evaluation, we show that our advisor is not only able to find partitionings that outperform existing approaches for automated partitioning design but that it also can easily adjust to different deployments. This is especially important in cloud setups where customers can easily migrate their cluster to a new set of (virtual) machines.
Supplementary Figure 5F from Discovery and Characterization of Novel Mutant FLT3 Kinase Inhibitors (2023)

Supplementary Figure 5F from Discovery and Characterization of Novel Mutant FLT3 Kinase Inhibitors
Aspects idéologiques et politiques du partenariat public-privé (1995)

Le Gales Patrick. Aspects ideologiques et politiques du partenariat public-prive. In: Revue d'economie financiere. Hors-serie, 1995. Partenariat public-prive et developpement territorial   . pp. 51-63.
Decomposition rates, synthesis, and spectral properties of a series of alkyl hyponitrites (1983)

A number of trans-alkyl hyponitrites (RON=NOR) weee synthesized and characterized. At 66.1 - 0.1 °C in isooctane and with millimolar to micromolar concentrations first-order kinetics were observed with half-lives (min) of 12.8 - 0.2 (CH3), 32.3 - 1.1 (2-C3H7), 15.0 - 0.3 (cyclohexyl), 25.2 - 1.2 (tert-butyl), 18.3 - 0.3 (tert-pentyl), 3.0 - 0.1 (benzyl), 11.2 - 0.5 (2-phenylethyl), and 5.5 - 0.3 (1-phenylethyl). The rate constants were concentration independent and showed little change with changes in solvent polarity or viscosity. Ultraviolet, magnetic resonance, infrared, and mass spectra for the new hyponitrites are reported. Most of the hyponitrites were highly crystalline solids that could be stored for long periods without change below 0 °C. © 1983, American Chemical Society. All rights reserved.
Asymmetric stochasticity of magnetization reversal dynamics in exchange-biased IrMn/CoFe Film (2012)

In this study, we investigated the stochastic nature of domain reversal dynamics in exchange-biased IrMn/CoFe film using a time-resolved Kerr microscope. Interestingly, the statistical distributions of the magnetization half-reversal times for both forward and backward applied fields show that the magnetization reversal dynamics is much more stochastic for the backward branch, where an applied field is parallel to the exchange-bias field direction. The enhanced stochasticity is ascribed to the large degree of magnetic disorder during backward reversal, which induces discrete and random Barkhausen jumps, whereas the forward branch reversal is dominated by a thermally activated depinning process caused by a single potential barrier. This result can be explained by the asymmetry of the magnetic disorder between both branches of a hysteresis loop.