gebhart/patrepeval huggingface dataset:
Educating for Leadership, Management and Teamwork (1995)

Abstract Beyond the mandatory aspects of technical competence, one of the most practical skills that Petroleum Engineering educators can teach students is how to work well with others. Because teamwork assignments in the classroom foster not only good communication skills but also advanced thinking skills, these assignments can provide students with the appropriate foundation for working in a corporate setting. Success in the workplace depends largely upon how well an employee gets along with others. In the oil and gas industry, the technically competent petroleum engineer who can coordinate and manage the efforts of other engineers performing traditional functions in the organization has the potential to rise to the top of the corporate ladder. Helping petroleum engineering students to become good managers and good communicators can be accomplished by teaching teamwork skills. However, students must see the relevance of teamwork and communication assignments to their profession; otherwise, they become resentful and fail to perform will. Experience has shown us that students learn more effectively when classroom activities are directly related to their interests and have significance for the students' future work. The synthesis of academic and industry perspectives can assure that classroom teamwork experiences are relevant and timely from the point of view of the faculty, students, and industry employers. This paper presents such a synthesis and provides additional information to help define the role of the petroleum engineer in today’s multi-discipline, cross-functional corporate environment. The paper also presents the most recent feedback from both industry representatives and academicians regarding the feasibility of including teamwork and leadership instruction in the undergraduate petroleum engineering curriculum. This feedback from industry and academia illustrates the need for continued cooperation and better communication between these two groups. Though the goals of both are similar (e.g., enhancing success and fostering excellence in the field), the means to reach those goals are often very different, and any number of representatives of the two groups would bring widely different perspectives into the discussion. To aid in understanding these similarities and differences in perspectives, this paper focuses on examining the issue from both sides.
Microreactor-Assisted Nanomaterial Processing: Scaling by an Equal up and Equal down Approach (2013)

Cite this article: Chang CH, Paul BK (2013) Microreactor-Assisted Nanomaterial Processing: Scaling by an Equal up and Equal down Approach. Chem Eng Process Tech 1(3): 1015. *Corresponding author Chih-Hung Chang, Oregon Process Innovation Center, Microproducts Breakthrough Institute, School of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, Oregon 97331, E-mail: Chih-Hung.Chang@oregonstate.edu
Minimum MSE Design for Multiuser MIMO Relay (2010)

We study a joint optimal design of transceiver and relaying architecture in terms of mean square error (MSE) performance for multi-user multiple-input multiple-output (MIMO) relaying system. We show a duality relationship in the design of MSE-optimal transceiver and relaying architecture. Based on that, we devise an alternating algorithm, which converges and provides a suboptimal joint design of transceiver and relaying. By simulation, we show that the proposed joint design improves on the average MSE performance of the existing transceiver and relaying architectures.
Room-Temperature Low-Threshold Lasing from Monolithically Integrated Nanostructured Porous Silicon Hybrid Microcavities (2018)

Silicon photonics would strongly benefit from monolithically integrated low-threshold silicon-based laser operating at room temperature, representing today the main challenge toward low-cost and power-efficient electronic-photonic integrated circuits. Here we demonstrate low-threshold lasing from fully transparent nanostructured porous silicon (PSi) monolithic microcavities (MCs) infiltrated with a polyfluorene derivative, namely, poly(9,9-di- n-octylfluorenyl-2,7-diyl) (PFO). The PFO-infiltrated PSiMCs support single-mode blue lasing at the resonance wavelength of 466 nm, with a line width of ∼1.3 nm and lasing threshold of 5 nJ (15 μJ/cm<sup>2</sup>), a value that is at the state of the art of PFO lasers. Furthermore, time-resolved photoluminescence shows a significant shortening (∼57%) of PFO emission lifetime in the PSiMCs, with respect to nonresonant PSi reference structures, confirming a dramatic variation of the radiative decay rate due to a Purcell effect. Our results, given also that blue lasing is a worst case for silicon photonics, are highly appealing for the development of low-cost, low-threshold silicon-based lasers with wavelengths tunable from visible to the near-infrared region by simple infiltration of suitable emitting polymers in monolithically integrated nanostructured PSiMCs.
8. Guanylyl Cyclase A-Targeted Gene Therapy Ameliorates Disease Progression in Autosomal Recessive Polycystic Kidney Disease (2015)

Although Polycystic Kidney Disease (PKD) is a leading cause of renal and hepatic pathologies, there are limited therapies available. PKD presents with cystic manifestations leading to organ enlargement, loss of functional parenchyma, progressive organ dysfunction and hypertension, ultimately leading to organ failure. Cardiac B-type natriuretic peptide (BNP) is central in the control of intravascular volume by regulating water and sodium homeostasis. Additionally, BNP has been characterized to counteract several key properties contributing to cystic disease progression such as; inhibiting fibroblast proliferation, preventing monocyte chemotaxis, antagonizing vasopressin (AVP)-mediated water reabsorption, and preventing renin-angiotensin-aldosterone activation. Along with its blood pressure-lowering propensity, BNP presents a promising therapeutic strategy in hindering the progression of PKD. We investigated the therapeutic effect of vector mediated BNP expression in the rat model of ARPKD (PCK). Littermate PCK neonates received placebo, or single intraperitoneal injection of adeno-associated virus 9 (AAV9) vectors at 1.0E+12 genome copies/kg, under the control of an internal CMV promoter. Three months post treatment, kidney weight was significantly reduced (TKW/BW 12.6±1.7* vs 14.5±2.0) in treated PCK, along with a significant reduction in renal cyst burden. Blood and urine analysis confirmed decreased disease with BNP treatment, with a nearly 50% reduction in 24 hour urine output, (8.8±3* vs 13.2±1 mL/24-hr), higher creatinine clearance (eGFR: 0.51±0.1* vs 0.26±0.2 mL/min), decreased proteinuria (490±270* vs 270±190 mg/dL), and increased urine concentrations of sodium (130±39* vs 85±20 mmol/L) and potassium (395.8±41* vs 282.1±75 mmol/L) in treated PCK, compared to controls, respectively. Excretion of renal injury markers, kidney injury molecule-1 and lipocalin-2, was lower in BNP-treated rats compared to controls. BNP treatment also preserved glomerular architecture, retarded basement membrane thickening and glomerular sclerosis in PCK. Real-time RT-PCR analysis demonstrated that BNP treatment significantly reduced renal and hepatic expression of the fibrosis-associated genes; Collagen, fibronectin, and transforming growth factor β. Furthermore, liver protection, in BNP-treated PCK, was observed through decreased expression of fibrosis marker desmin, and galectin-3, along with decreased cyst-index. Additionally, echocardiography demonstrated preserved cardiac function with treatment (ejection fraction: 78±5 * vs 73±5%) at three months, though both groups remained normotensive. Together, these observations indicate that a single intraperitoneal AAV9 injection elicits therapeutic benefit in protecting against declining hepatic and renal function, remodeling of healthy parenchyma, and increased cyst burden, while providing cardiac protection. The present study further suggests that sustained GC-A activation provides a novel opportunity for the treatment of polycystic kidney and liver diseases.±±
Involvement of the high-affinity receptor for IgG (Fc gamma RI; CD64) in enhanced tumor cell cytotoxicity of neutrophils during granulocyte colony-stimulating factor therapy (1993)

Three different classes of Fc receptors for IgG (Fc gamma R) are currently distinguished in humans, of which polymorphonuclear phagocytes (PMN) normally express both low-affinity receptor classes--Fc gamma RII (CD32) and Fc gamma RIII (CD16). During therapy with granulocyte colony-stimulating factor (G-CSF), neutrophils from patients with various malignancies and different hematologic disorders were found to additionally express high levels of the receptor with high affinity for IgG (Fc gamma RI; CD64). For these patients, the relative fluorescence intensity (rFI) for Fc gamma RI was 5.3 (range, 1.7 to 10.3; n = 19), compared with 1.0 (range, 1.0 to 1.1; n = 8) for healthy donors. The expression of Fc gamma RI during G-CSF therapy could be confirmed by using a panel of six CD64-specific antibodies, and by showing mRNA for Fc gamma RI. So far, three genes for Fc gamma RI have been identified, encoding four distinct transcription products. By reverse transcriptase-polymerase chain reaction technology, transcripts for both membrane-associated isoforms (hFc gamma RIa and hFc gamma RIb2) could be detected. The functional activity of Fc gamma RI on PMN during G-CSF therapy was shown by measuring binding of monomeric human IgG and antibody-dependent cellular cytotoxicity (ADCC). Thus, Fc gamma RI-positive neutrophils displayed enhanced ADCC activity to glioma (A1207), squamous cell (A431), and ovarian (SK-ov3) carcinoma cell lines. The involvement of Fc gamma RI in this increased cytotoxic activity was shown by blocking Fc gamma receptors with monoclonal antibodies, and by using F(ab')2 x F(ab')2-bispecific antibodies with specificities against tumor-related antigens and Fc gamma RI, resulting in solely Fc gamma RI-mediated cytotoxicity. Therapeutically, this additional Fc receptor on PMN may increase the efficacy of experimental antibody therapy.
Hypersensitivity reactions to human papillomavirus vaccine in Australian schoolgirls: retrospective cohort study (2008)

True hypersensitivity to the quadrivalent human papillomavirus vaccine in Australian schoolgirls was uncommon and most tolerated subsequent doses.
Time-Refraction Optics at Single Cycle Modulation (2023)

We present an experimental study of optical time-refraction in single-cycle time-interfaces. Specifically, we study the propagation of a probe pulse through a sample undergoing large refractive index changes induced by an intense ultra-short modulator pulse.
Effects of amiprophosmethyl on massive and limited calcium loading of maize mitochondria (1983)

In maize mitochondria the effect of the herbicide amiprophosmethyl was studied on massive and limited Ca2+-loading and on mitochondrial energy transduction. Under massive Ca2+-loading conditions amiprophosmethyl inhibited the Ca2+ transport system directly without a significant effect on the respiratory chain, the membrane potential or Ca2+ efflux. Under limited Ca2+-loading conditions an increased Ca2+ efflux was noted, which could be partially responsible for the inhibition of the net Ca2+ accumulation.
CEP89 is required for mitochondrial metabolism and neuronal function in man and fly (2013)

It is estimated that the human mitochondrial proteome consists of 1000-1500 distinct proteins. The majority of these support the various biochemical pathways that are active in these organelles. Individuals with an oxidative phosphorylation disorder of unknown cause provide a unique opportunity to identify novel genes implicated in mitochondrial biology. We identified a homozygous deletion of CEP89 in a patient with isolated complex IV deficiency, intellectual disability and multisystemic problems. CEP89 is a ubiquitously expressed and highly conserved gene of unknown function. Immunocytochemistry and cellular fractionation experiments showed that CEP89 is present both in the cytosol and in the mitochondrial intermembrane space. Furthermore, we ascertained in vitro that downregulation of CEP89 resulted in a severe decrease in complex IV in-gel activity and altered mobility, suggesting that the complex is aberrantly formed. Two-dimensional BN-SDS gel analysis revealed that CEP89 associates with a high-molecular weight complex. Together, these data confirm a role for CEP89 in mitochondrial metabolism. In addition, we modeled CEP89 loss of function in Drosophila. Ubiquitous knockdown of fly Cep89 decreased complex IV activity and resulted in complete lethality. Furthermore, Cep89 is required for mitochondrial integrity, membrane depolarization and synaptic transmission of photoreceptor neurons, and for (sub)synaptic organization of the larval neuromuscular junction. Finally, we tested neuronal Cep89 knockdown flies in the light-off jump reflex habituation assay, which revealed its role in learning. We conclude that CEP89 proteins play an important role in mitochondrial metabolism, especially complex IV activity, and are required for neuronal and cognitive function across evolution.
Analysis of the RATAN-600 radiotelescope antenna with a multilevel Physical Optics algorithm (2011)

The RATAN-600 antenna is a flexible multireflector system composed of reflectors of very large dimensions. An extended system, with improved performance in the millimetric range, includes a focal receiver array. Accurate electromagnetic analysis of such a system, and simulation of three-dimensional (3D) patterns, represents a substantial computational challenge. A fast Physical Optics method based on a multilevel subdivision of the surfaces of integration is proposed to address this problem. This method allows to perform Physical Optics integrals with a computational complexity comparable to that of the Fast Fourier Transform. The algorithm and initial numerical results of its application to the RATAN-600 antenna system are presented.
An Improved Synthesis of 5′‐Amino‐5′‐deoxyguanosine. (2002)

Abstract For Abstract see ChemInform Abstract in Full Text.
A Practical Form of Exponentially-Weighted H&infin; Adaptive Filters (2014)

This paper examines the problem of exponentially-weighted H&infin; adaptive filtering and shows that its suboptimal solution reduces to a recursive algorithm which is slightly different from the RLS algorithm. Based on this similarity, its fast array form is immediately obtained by following the derivation of the fast RLS array algorithm. Also a theoretical expression for its steady-state mean-square error is provided. Several numerical examples indicate that the exponentially-weighted H&infin; filter can achieve a proper balance between H&infin; and H2 (least squares) filtering criteria.
Crystallization and Preliminary X-Ray Crystallographic Studies of Trypanosoma brucei Prostaglandin F2 Synthase (2002)

Prostaglandin F(2 alpha) is a potent mediator of various physiological and pathological processes. Trypanosoma brucei prostaglandin F(2 alpha) synthase (TbPGFS) catalyzes the NADPH-dependent reduction of 9,11-endoperoxide PGH(2) to PGF(2 alpha), and could thus be involved in the elevation of the PGF(2 alpha) concentration during African trypanosomiasis. In the present report, the purification and crystallization of recombinant TbPGFS are described. The active recombinant enzyme was crystallized by the hanging-drop vapor-diffusion meth-od using ammonium sulfate as a precipitant. The crystal belonged to a tetragonal space group, P4(1)2(1)2 or P4(3)2(1)2, with unit-cell parameters of a = b = 112.3 A, and c = 140.0 A. Native data up to 2.6 A resolution were collected from the crystal using our home facility.
Low number of neurosecretory vesicles in neuroblastoma impairs massive catecholamine release and prevents hypertension (2022)

The low amount of neurosecretory vesicles in NB cytoplasm prevents catecholamine storage and lead to their rapid transformation by catechol O-methyltransferase into metanephrines that diffuse in blood. Hence, in contrast to PHEO/PGL, catecholamines are not secreted massively in the blood, which explains why systemic hypertension is not observed in most patients with NB.
Anti-Turing Machine (2019)

The invention of CPU-centric computing paradigm was incredible breakthrough of computer science that revolutionized our everyday life dramatically. However, the CPU- centric paradigm is based on the Turing machine concept and, as a result, expensive and power-hungry data transferring between the memory and CPU core is inevitable operation. Anti-Turing machine paradigm can be based on two fundamental principles: (1) data-centric computing, and (2) decentralized computing. Anti-Turing machine is able to execute a special type of programs. The commands of such program have to be addressed to the 2D or 3D persistent memory space is able to process data in-place. This program should not define the position or structure of data but it has to define the goal of data processing activity. Generally speaking, it needs to consider the whole memory space like the data transformation space. But the data placement, particular algorithm implementation, and strategy of algorithm execution are out of scope of the program.
Silicon Etching and Etch Techniques for NEMs and MEMs (2012)

Fabrication of precision micro- and nanoscale structures in silicon demands exacting control over pattern transfer during etching. The most utilized method to enable this pattern transfer anisotropically is plasma etching with an inductively couple plasma reactive ion etcher. When properly used, these machines can etch high-aspect-ratio structures in silicon that are hundreds of microns in height to tens of nanometers in width. The work presented here will detail how to tune parameters associated with a plasma etcher and manipulate the gas chemistry to achieve and control anisotropic silicon etches at both micro- and nanoscale. Etch masks that ensure a high pattern transfer fidelity and complement the gas chemistries employed here will also be detailed. Finally several etching techniques that use the principles detailed to fabricate extraordinary structures in silicon will be described.
Genetic Network Programming with Automatically Generated Macro Nodes of Variable Size (2006)

Recently, Genetic Network Programming (GNP) has been proposed as one of the evolutionary algorithms. It represents its solutions as directed graph structures and the distinguished abilities have been shown. However, when we apply GNP to complex problems like the real world one, GNP must have robustness against the changes of environments and evolve quickly. Therefore, we introduced Automatically Generated Macro Nodes (AGMs) to GNP (GNP with AGMs). Actually GNP with AGMs has shown higher performances than the conventional GNP in terms of the fitness and the speed of evolution. In this paper, a new mechanism, AGMs with variable size, is introduced to GNP. Conventional AGMs have the fixed number of nodes and they evolve using only genetic operations, while a new method allows AGM to add nodes by necessity and delete nodes which do not contribute to the evolution of the AGM. The proposed GNP with AGMs of variable size is expected to evolve effectively and efficiently when it is applied to agent systems and also expected to make better behavior sequences of agents more easily than the conventional GNP algorithm. In the simulations, the proposed and conventional methods are applied to a tileworld problem and they are compared with each other. From the results, GNP with AGMs of variable size shows better fitness than GNP with AGMs of fixed size and the conventional GNP when adapting ten different environments.
EGF816, an irreversible mutant-selective EGFR inhibitor, is effective in NSCLC with both primary activating and T790M-mediated resistant EGFR mutations (2016)

NSCLC patients carrying oncogenic EGFR mutations initially respond to EGFR targeted therapy. However, duration of the response is limited due to dose limiting toxicities and acquired resistance. EGF816 is a novel, irreversible mutant-selective EGFR inhibitor that specifically targets both primary activating and the T790M acquired resistant EGFR mutations, while sparing wild-type (WT) EGFR. EGF816 potently inhibits the most common EGFR mutations L858R, Ex19del and T790M in vitro which translating into strong tumor regressions in vivo in several patient-derived xenografts (PDX). Of note, EGF816 also demonstrated antitumor activity in an exon 20 insertion mutant model. At levels above efficacious doses, EGF816 showed minimal inhibition of WT EGFR receptor and was well-tolerated. In single dose studies, EGF816 showed sustained inhibition of pEGFR, consistent with its irreversible binding mechanism. In addition, EGF816 in combination with a cMET inhibitor demonstrated durable efficacy in a model that became resistant to first generation EGFR inhibitors via cMET activation. EGF816 has shown promising clinical efficacy in phase I trials.
Image Capture Circuits in CMOS (2005)

CMOS image sensors are a second-generation solidstate imaging technology. CMOS active pixel sensors have performance competitive with CCD technology, and offer advantages in on-chip functionality, system power reduction, cost and miniaturization. CMOS VLSI circuits for imaging and readout, and on-chip integration of ADC and smart functions will be addressed.
Effect of Pyridyl Donors in the Chelation of Aluminum(III), Gallium(III), and Indium(III) (1997)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionEffect of Pyridyl Donors in the Chelation of Aluminum(III), Gallium(III), and Indium(III)P. Caravan, Steven J. Rettig, and Chris OrvigCite this: Inorg. Chem. 1997, 36, 21, 4912Publication Date (Web):October 8, 1997Publication History Published online8 October 1997Published inissue 1 October 1997https://pubs.acs.org/doi/10.1021/ic9708778https://doi.org/10.1021/ic9708778correctionACS PublicationsCopyright © 1997 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views327Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (14 KB) Get e-Alertsclose Get e-Alerts
Frailty as a Novel Predictor of Mortality and Hospitalization in Individuals of All Ages Undergoing Hemodialysis (2013)

Adults of all ages undergoing hemodialysis have a high prevalence of frailty, more than five times as high as community-dwelling older adults. In this population, regardless of age, frailty is a strong, independent predictor of mortality and number of hospitalizations.