gebhart/patrepeval huggingface dataset:
Adaptive Array of Phase-Locked Fiber Collimators: Analysis and Experimental Demonstration (2009)

We discuss development and integration of a coherent fiber array system composed of densely packed fiber collimators with built-in capabilities for adaptive wavefront phase piston and tilt control at each fiber collimator. In this system, multi-channel fiber-integrated phase shifters are used for phase locking of seven fiber collimators and the precompensation of laboratory-generated turbulence-induced phase aberrations. Controllable <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</i> and <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">y</i> displacements of the fiber tips in the fiber collimator array provide additional adaptive compensation of the tip and tilt phase aberration components. An additional control system is utilized for equalization of the intensity of each of the fiber collimator beams. All three control systems are based on the stochastic parallel gradient descent optimization technique. The paper presents the first experimental results of adaptive dynamic phase distortion compensation with an adaptive phase-locked fiber collimator array system.
Plasma Procalcitonin Is Associated with Obesity, Insulin Resistance, and the Metabolic Syndrome (2010)

Elevated plasma procalcitonin levels in the normal range are associated with measures of obesity, insulin resistance, and MS in the general population.
3D Radiation Pattern Reconfigurable Phased Array for Transmission Angle Sensing in 5G Mobile Communication (2018)

This paper proposes a 3D radiation pattern reconfigurable antenna (RPRA) and a reconfigurable phased array (RPA) for 5G mobile communication. The antenna and array are working at 28 GHz, which is selected as a 5G communication band in many countries. The proposed phased array will be applied as sensors to find out the optimal transmitting–receiving angle in a randomly changed cellular wireless scenarios. The RPRA and RPA are fed by Substrate Integrated Waveguide (SIW) and have three switchable radiation modes: Broadside 1, Broadside 2 and Endfire. The three modes correspond to three different radiation patterns and each of them covers a different area in the Azimuth plane. An eight-element phased array constructed by the proposed RPRA, which is able to switch beam in Azimuth plane and scan in the Elevation plane, is also presented in this paper. The proposed RPA is able to provide much higher spatial coverage than the conventional phased arrays and without additional feeding and phase shifting networks. The beam switching is realized by the PIN diodes. The proposed antenna and array have planer structures and require small clearance on the ground plane which makes them compatible with mobile phones. The simulations show good performance for both RPRA and RPA.
Effects of Surface Modification and Moisture on the Rates of Charge Transfer between Metals and Organic Materials (2004)

This report is a study of the kinetics of contact charging resulting from the rolling of millimeter-sized metallic spheres on flat surfaces of polystyrene (PS). Charging was studied (i) for different values of the relative humidity (RH) of the air in contact with the system, (ii) in acidic and basic atmospheres, and (iii) for a series of PS surfaces oxidized to different degrees. The rates of charging increased with increasing RH; they were higher in basic atmospheres than in neutral or acidic ones and correlated with the numbers of hydrophilic groups on the surface of the polymer. These findings are consistent with a mechanism that implicates a thin film of water on the surface of PS as an important element of tribocharging in this system.
ChemInform Abstract: Asymmetric Decarboxylative Allylation of Oxindoles. (2011)

Abstract The reversal in stereoselectivity correlates with the size of the oxindole substituent.
Importance of Periodontal Disease in the Kidney Patient (2002)

End-stage renal disease (ESRD) patients on hemodialysis experience a greatly increased rate of atherosclerotic complications. In both hemodialysis and general populations, it has become evident that inflammation plays a central role in the pathogenesis of atherosclerotic complications. C-reactive protein (CRP), the major acute phase protein in man, has been found to predict all-cause and cardiovascular mortality in ESRD patients on hemodialysis maintenance therapy. Hepatic CRP synthesis is upregulated by proinflammatory cytokines released locally at sites of infection or inflammation, although many patients experience elevated CRP values in the absence of overt infection or inflammation. Destructive periodontal diseases in the general population have been associated with both an increased prevalence of atherosclerotic complications and an elevation in serum CRP values. In view of the prevalence of destructive periodontal diseases in the general population, and since periodontal evaluations are normally not performed as part of a medical assessment, destructive periodontal diseases may be an over looked source of inflammation in ESRD patients on hemodialysis therapy. The intent of this report is to review the possible role destructive periodontal diseases and associated periodontal infections may play in the management of the ESRD patient on hemodialysis maintenance therapy.
Cognitive control channels: from concept to identification of implementation options (2012)

Recent effort related to cognitive radio systems has lead to an in-depth analysis of context information management and exploitation based on a cognitive control channel for enhancement of management needed for, say, suitable link selection in a heterogeneous radio framework, dynamic radio resource management, and distributed sensing. Concerning the actual implementation of such a CCC, the focus was recently moved toward an in-band solution, where the information is transported building on existing radio access technologies. In this scope, this article illustrates relevant technical scenarios in which CCCs can be exploited and outlines a set of derived system requirements. The article provides an overview of various possible RAT independent and dependent implementation options, such as Diameter, distributed agents, 3GPP radio resource control (RRC) mechanisms, IEEE 802.21, IEEE 802.11, WiMedia UWB, and Bluetooth. The advantages and drawbacks of the various options are discussed.
Mimics of tryptophan synthetase and of biochemical dehydroalanine formation (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMimics of tryptophan synthetase and of biochemical dehydroalanine formationWayne Weiner, Jeffrey Winkler, Steven C. Zimmerman, Anthony W. Czarnik, and Ronald BreslowCite this: J. Am. Chem. Soc. 1985, 107, 13, 4093–4094Publication Date (Print):June 1, 1985Publication History Published online1 May 2002Published inissue 1 June 1985https://pubs.acs.org/doi/10.1021/ja00299a064https://doi.org/10.1021/ja00299a064research-articleACS PublicationsRequest reuse permissionsArticle Views354Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
LOX-1, mtDNA damage, and NLRP3 inflammasome activation in macrophages: implications in atherogenesis (2014)

This study based on THP-1 macrophages and primary macrophages indicates that LOX-1-mediated autophagy and mtDNA damage play an essential role in NLRP3 inflammasome activation in inflammatory disease states.
Mapping electrostatic potential across an AlGaN/InGaN/AlGaN diode by electron holography (2000)

Electron holography has been used to image electrostatic potential variations across an AlGaN/InGaN/AlGaN heterojunction diode. Features in the energy profile have been interpreted in terms of the expected built-in voltage across the p-n junction of the diode as well as contributions from the spontaneous and piezoelectric polarization fields within the material. Additional profile features indicate the presence of two-dimensional electron gas at the upper interface of the InGaN well, and evidence for hole accumulation close to the lower interface.
Arsenate Removal by Iron (Hydr)Oxide Modified Granulated Activated Carbon: Modeling Arsenate Breakthrough with the Pore Surface Diffusion Model (2008)

Abstract This study focuses on evaluating the feasibility of using pore surface diffusion model (PSDM) to successfully predict arsenate breakthrough curves of continuous flow packed columns containing granulated activated carbon modified with iron (hydr)oxide. Two different treatment methods were used to synthesize modified granulated activated carbon media (M-GAC): (i) Fe(III)/alcohol treatment method (M-3–15), and (ii) KMnO4/Fe(II) treatment method (Mn-0.5–15). Adsorption capacities were obtained and fitted by Freundlich isotherm model () for initial arsenate concentration of 120 µg As(V)/L at either pH = 7.3±0.1 for M-3–15 or pH = 8.3±0.1 for Mn-0.5–15 in 10 mM NaHCO3 buffered ultrapure water. Short bed adsorber (SBA) columns tests were conducted at the same water quality condition as the batch experiments and used to validate the PSDM.
Electrical properties and TDDB performance of Cu interconnects using ALD Ta(Al)N barrier and Ru liner for 7nm node and beyond (2016)

We have integrated ALD barrier and Ru liner for novel interconnect integration and have evaluated electrical properties and time dependent dielectric breakdown (TDDB). RC and via resistance were reduced by the ALD barrier, and particularly it was confirmed that TDDB performance can be improved by using ALD TaAlN with an ultrathin film. Accordingly, ALD TaAlN barrier and CVD Ru liner are attractive barrier/liner combination for next generation interconnect integration schemes.
A1064. EFFECT OF CONCOMITANT LATISSIMUS DORSI TRANSFER ON JOINT REACTION FORCE FOR REVERSE TOTAL SHOULDER ARTHROPLASTY (2011)

Although reverse total shoulder arthroplasty (TSA) may restore shoulder abduction and forward flexion in the setting of a massive rotator cuff tear, the ability to use the extremity for ADL’s is often limited by external rotation weakness. Even though the reverse TSA restores abduction, the patient may be unable to bring the hand to his or her mouth because with the elbow flexed the weight of the hand causes the shoulder to fall into internal rotation. Concomitant transfer of latissimus dorsi (LDT) to the posterior greater tuberosity is a solution advocated by some surgeons. It is hypothesized that this inferiorly-directed force partially counteracts the superiorly-directed force of the deltoid, resulting in decreased shear forces on the glenoid baseplate-bone interface. Three cadaver shoulder specimens were dissected and implanted with the reverse TSA. The rotator cuff was completely released to simulate a massive rotator cuff tear. Each shoulder was mounted in a shoulder controller that simulates neuromuscular control and replicates in vivo glenohumeral kinematics. The controller utilizes an optical, three dimensional tracking system. The humerus was weighted to simulate the full mass of the upper extremity and stepper motors were connected to the insertion points of the anterior, middle and posterior divisions of the deltoid by Spectra ® cord. Simulated active abduction in the scapular plane was performed using position closed-loop feedback control. The joint reaction force at the glenosphere was measured at 5° intervals from 30°–70°. A fourth stepper motor was then connected to the greater tuberosity with 2.73kg applied to simulate a LDT and the test was repeated. Five trials were performed under each condition. Four-factor ANOVA statistical analysis with Bonferroni correction and α = 0.05 was performed. After simulated LDT the JRF demonstrated an increase in magnitude at abduction angles between 30° and 65° inclusive (p=0.033). The superiorly-directed shear force was significantly decreased as a result of the LDT between 45° and 70° (p In this model of reverse total shoulder arthroplasty concomitant transfer of latissimus dorsi decreased the superiorly-directed shear force. In addition to providing improved external rotation strength, these lower shear forces may have a protective effect on baseplate fixation by reducing the risk of failure in shear. This may provide additional justification for the transfer. Although superior shear was decreased, total JRF was increased as a result of an increase in the compressive component. Further investigation is needed to determine the potential gain in joint stability and whether the glenoid bone can support such elevated compressive forces. Additionally, the force required in the anterior and middle deltoid was increased after the LDT. This indicates the need for sufficient deltoid strength and rehabilitation.
OPTIMIZATION OF FREQUENCY-RESPONSE MASKING BASED FIR FILTERS (2003)

A very efficient technique to drastically reduce the number of multipliers and adders in implementing linear-phase finite-impulse response (FIR) digital filters in applications demanding a narrow transition band is to use the frequency-response masking (FRM) approach originally introduced by Lim. The arithmetic complexity can be even further reduced using a common filter part for constructing the masking filters originally proposed by Lim and Lian. A drawback in the above-mentioned original FRM synthesis techniques is that the subfilters in the overall implementations are separately designed. In order to further reduce the arithmetic complexity in these two FRM approaches, the following two-step optimization technique is proposed for simultaneously optimizing the subfilters. At the first step, a good suboptimal solution is found by using a simple iterative algorithm. At the second step, this solution is then used as a start-up solution for further optimization being carried out by using an efficient unconstrained nonlinear optimization algorithm. An example taken from the literature illustrates that both the number of multipliers and the number of adders for the resulting optimized filter are less than 80% compared with those of the FRM filter obtained using the original FRM design schemes in the case where the masking filters are separately implemented. If a common filter part is used for realizing the masking filters, then an additional reduction of more than 10% is achieved compared with the optimized design with separately implemented masking filters.
A retrospective case series of electroconvulsive therapy in the management of comorbid depression and anorexia nervosa (2019)

ECT is safe and well tolerated in AN with severe comorbid treatment resistant MDD and/or with increased suicide risk. Many AN patients undergoing ECT may be remitted at long-term follow-up.
Sonochemistry as a tool for preparation of porous metal oxides (2002)

Abstract The porous metal oxides are an important class of materials, because the surface area/volume ratio of a material is increased by many fold, making them very useful in surface-related applications. The mesoporous materials were discovered in the 1990s, and since then they have been excellent candidates for materials science research. These mesoporous materials are prepared by hydrolyzing the inorganic precursor (usually metal alkoxide) in an acid, basic, or neutral medium in the presence of an organic structure-directing agent, the surfactant, in a conventional method. Recently, we have demonstrated that the sonochemical technique can be employed for the synthesis of mesoporous metal oxides. The sonochemical method reduced the time period required for such synthesis by many fold, and also produced more stable structures. We got excellent results with silica, titania, yittria-stabilized zirconia (YSZ), and Fe 2 O 3 . We also used an inorganic precursor other than an alkoxide for the preparation of mesoporous metal oxides. In this article, we present some of the recent results on this topic.
Effect of Isoxuprine on Uteroplacental Blood Flow in Normal and Hypertensive Patients during the Last Trimester of Pregnancy (1975)

Suonio, S., Jalkanen, M., Olkkonen, H. &amp; Castrén, O. (Dept. of Obstetrics and Gynaecology, University Central Hospital, Kuopio, Finland). Effect of isoxu‐prine on uteroplacental blood flow in normal and hypertensive patients during the last trimester of pregnancy . Int J Gynaecol Obstet 13 : 225–228, 1975. The uteroplacental blood flow was evaluated in 15 normal and 12 hypertensive patients in late pregnancy using the 99m Tc accumulation method before and after a single i.m. dose of 5 mg of isoxuprine. In the group of normal patients there was a statistically significant 35 per cent mean increase in the accumulation rate, but in the group of hypertensive patients no significant change was found. Other haemodynamic variables measured were the maternal heart rate and systolic and diastolic blood pressures. There was a statistically significant increase in the heart rate in both patient groups after medication. No significant changes were observed in systolic pressure. In diastolic pressure a significant fall was found in normal, but not in hypertensive patients. According to the results, the therapeutically positive maternal vascular response to isoxuprine does not take place in pregnancy complicated by hypertensive disease.
Mobile Coverage in Rural Sweden: Analysis of a Comparative Measurement Campaign (2021)

Under the umbrella of 1G to 5G, different technologies have been used to provide mobile communication. Various technologies are being proposed to bring a person in remote area under coverage. However, a statistical analysis on what these users get from already existing technologies has not been carried out. We fill this gap by carrying out such a study using a measurement campaign, where we present a framework for analyzing mobile signal strength experienced at the user end. Measurements are taken throughout the Norrbotten county, the northernmost county in Sweden, using mobile phones recording various parameters at regular intervals. Based on measured signal strength, a coverage map has been made via inverse distance weighting (IDW) interpolation. Based on the coverage map, various analyses are carried out on signal strength over residential areas and roads of Norrbotten. Overall, we lay a framework to analyze and quantify the effect of signal strength on users.
Phase I study of a novel, pharmacokinetically derived schedule of flavopiridol in acute leukemias: Clinical efficacy including hyperacute tumor lysis, pharmacokinetics, and pharmacodynamics (2006)

6568 Background: Flavopiridol is a cyclin dependent kinase inhibitor with in vitro activity in many cancer cell lines. However, phase I/II studies of either 24 or 72-hour continuous infusion schedules demonstrated no significant clinical activity. Discordant binding of flavopiridol to human plasma proteins as compared to fetal calf serum prompted us to perform pharmacokinetic modeling studies which suggested that optimal dosing would be a 30 min IV bolus followed by 4 hr IV infusion. With this schedule, our group has observed impressive clinical activity in refractory CLL. Methods: We intensified this schedule for relapsed or refractory adult AML and ALL patients (pts) to administer an IV bolus over 30 min followed by an infusion over 4 hrs on 3 consecutive days in a phase I trial. Results: To date, 10 pts have been treated at 2 dose levels. Pts had relapsed/refractory AML (N=6) or ALL (N=4) and were 25–77 yrs old. 4 pts received flavopiridol at 20 mg/m2 IV bolus and 30 mg/m2 infusion; 6 received 30 mg/m2 bolus followed by 35 mg/m2 infusion. The most significant toxicity was tumor lysis; treatment was well tolerated, and toxicities were similar to those previously reported by our group with the single day dosing schedule used in CLL. Plasma levels were 1–2 μM during the infusion (N=7) and declined with a terminal half life comparable to that previously reported with a 72 hr infusion. Significant anti-leukemic activity was seen in 5/7 evaluable pts at both dose levels. Tumor lysis was seen in both ALL and AML (see table ). Downregulation of Mcl-1 protein by immunoblotting was seen in 2/3 pts tested to date. Conclusions: Single agent flavopiridol given with this novel, pharmacologically modeled schedule has clinical activity in pts with relapsed/refractory ALL and AML. Further study in acute leukemia using this schedule is warranted; dose escalation to the current trial is ongoing. (NCI U01 CA 76576–05) [Table: see text] No significant financial relationships to disclose.
Molecular spin qubits based on lanthanide ions encapsulated in cubic polyoxopalladates: design criteria to enhance quantum coherence (2015)

Axial compression and a magnetic field can help to get coherent spin qubits.
Using Network Component Analysis to Dissect Regulatory Networks Mediated by Transcription Factors in Yeast (2009)

Understanding the relationship between genetic variation and gene expression is a central question in genetics. With the availability of data from high-throughput technologies such as ChIP-Chip, expression, and genotyping arrays, we can begin to not only identify associations but to understand how genetic variations perturb the underlying transcription regulatory networks to induce differential gene expression. In this study, we describe a simple model of transcription regulation where the expression of a gene is completely characterized by two properties: the concentrations and promoter affinities of active transcription factors. We devise a method that extends Network Component Analysis (NCA) to determine how genetic variations in the form of single nucleotide polymorphisms (SNPs) perturb these two properties. Applying our method to a segregating population of Saccharomyces cerevisiae, we found statistically significant examples of trans-acting SNPs located in regulatory hotspots that perturb transcription factor concentrations and affinities for target promoters to cause global differential expression and cis-acting genetic variations that perturb the promoter affinities of transcription factors on a single gene to cause local differential expression. Although many genetic variations linked to gene expressions have been identified, it is not clear how they perturb the underlying regulatory networks that govern gene expression. Our work begins to fill this void by showing that many genetic variations affect the concentrations of active transcription factors in a cell and their affinities for target promoters. Understanding the effects of these perturbations can help us to paint a more complete picture of the complex landscape of transcription regulation. The software package implementing the algorithms discussed in this work is available as a MATLAB package upon request.