gebhart/patrepeval huggingface dataset:
Inside Cover: Enantiopure Narrow Bite‐Angle POP Ligands: Synthesis and Catalytic Performance in Asymmetric Hydroformylations and Hydrogenations (Chem. Eur. J. 47/2014) (2014)

Narrow-bite-angle 1,1-P–OP ligands containing a stereogenic carbon atom in the backbone have been developed. In their Full Paper on page 15375 ff., A. Vidal-Ferran et al. describe the application of these ligands in rhodium-catalyzed hydroformylations and hydrogenations.
EFFICIENT AND LONG-LASTING ADENO-ASSOCIATED VIRUS 8 (AAV8) VECTOR –MEDIATED TRANSGENE EXPRESSION IN HEART TRANSPLANT MYOCARDIUM (2008)

Jokinen, J J.; Nykänen, A I.; Pajusola, K; Tuuminen, R; Krebs, R; Soronen, J; Alitalo, K; Lemström, K B. Author Information
Si/SiO<sub>2</sub> and SiC/SiO<sub>2</sub> Interfaces for MOSFETs – Challenges and Advances (2006)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Study of the electronic transport at all scales of the C-LiFePO4 composite material (2011)

LGEP 2011 ID = 829
705 Relationship between Porosity and Compression Properties of Porous Aluminum Fabricated by Friction Powder Compaction Process (2013)

Open-cell porous aluminum (Al) was fabricated by friction powder compaction (FPC) process without using external heat sources In this process, powder mixture of Al powder and sodium chloride (NaCl) powder as spacer particle was used as starting material The compacting and sintering of the mixture were conducted only by rotating tool plunged into a die and mixture NaCl was removed by placing the sintered mixture m water In this study, pore structures of obtained porous Al were nondestructively observed by X-ray CT In addition, a relationship between porosity and compression properties of obtained porous Al were investigated
Slow penetration for characterizing concrete for digital fabrication (2022)

Digital fabrication processes with concrete require a specific yield stress evolution after placing. This paper shows that this goal can be achieved with displacement controlled continuous slow penetration methods, and gives a model understanding and specific suggestions for measurement. It is found that the force recorded in continuous and point-wise penetration tests with a conical tool moving at a slow rate scales linearly and over multiple decades with independent measurements of yield stress carried out using uniaxial compression and vane test. A model adapted from soil-mechanical stability predicts the bearing capacity factor that relates the penetration force to yield stress. The experimental value agrees with the predicted one for an undrained/plastic material. The measurements indicate a yield stress validity range of 1–200 kPa and as low as 0.1 kPa with consideration of depth dependency. This range is the one of greatest interest for structural build-up in digital fabrication during production.
Development of wound SiCBNx/SiNx/SiC with near stoichiometric SiC matrix via LSI process (2016)

In order to develop SiC/SiC ceramic matrix composites with a low porosity, liquid silicon infiltration(LSI) was chosen as a technique, characterized by short processing times. To create the matrix, a tailoredphenolic resin containing ß-naphthol units was synthesized and infiltrated in wound fiber preforms,thermally cured, pyrolysed and siliconized. The aim is to obtain a high carbon yield during pyrolysis andto create a dense carbon foam between the SiC fibers. Instead of a classic liquid silicon infiltration viacapillary forces through a carbon block-like microstructure, this foam promotes a softer infiltration withless fiber degradation and a maximized carbon conversion to near stoichiometric SiC. To protect the SiCfibers from an attack of the liquid silicon and to simultaneously provide a weak fiber matrix bonding, aBNx/SiNxfiber coating was chosen. The coating was applied by means of low-pressure chemical vapordeposition (LPCVD) using gaseous chlorine free precursors.
A new strategy for studyingin vitro the drug susceptibility of clinical isolates of human hepatitis B virus (2004)

International audience
Sensing power MOSFET junction temperature using circuit output current ringing decay (2013)

Junction temperature sensing requirements for fast MOSFET junction temperature control and high power fast switching power converter protection are not easily met with non-intrusive techniques. This paper presents a non-invasive circuit model-based sensing method suitable for a high bandwidth, hard-switching converter power MOSFET junction temperature estimation without any additional temperature detector. For the purpose of demonstrating MOSFET junction temperature sensing, a chopper circuit is used. The ringing superimposed with a circuit load current is used for MOSFET junction temperature estimation. A `gate drive-R <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">DS-on</sub> -L-C' resonant model is implemented indicating the mechanism of power MOSFET turn-on dynamics. Modeling includes the gate-drive output parasitics, power MOSFET intrinsic parameters, PCB parasitics and load parasitics. To evaluate the methodology, LTSpice Simulation and experimental results are studied.
Preliminary studies for the development of superconducting composite wires (1989)

The results reported are part of a larger effort, the basic aim of which is to develop high-T/sub c/ superconducting composite wires, films, and thin-gauge panels with large current carrying capacity and engineered thermal and mechanical properties. The results relate to the following aspects of this ongoing research effort: the sputtering parameters used to deposit Bi-Sr-Ca-Cu-O films on MgO and other substrates; a dipping technique to produce Bi-Sr-Ca-Cu-O superconducting layers and wires; the postannealing heat treatments; the characterization of the microstructure and crystallographic features of the deposited films; and the superconducting properties of the films, layers, and wires.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Abstract 4955: Isolation and characterization of circulating tumor cells (CTCs) in breast and prostate cancer: Comparison of Harpoon CTC assay performance with the CellSearch CTC Test (2016)

Abstract Circulating tumor cells (CTCs) can provide important information about a patient's prognosis. Currently, the CELLSEARCH® CTC Test (hereafter referred to as CS) is the only US Food and Drug Administration-cleared assay for isolating and enumerating CTCs. This technology uses a CTC antigen-dependent method to isolate CTCs that may limit its ability to detect CTCs with low or no epithelial cell adhesion molecule (EpCAM) expression. We evaluated the Harpoon CTC Isolator and Chip, which uses an antigen-independent, negative depletion method to enrich CTCs from patient blood samples. As a result of the negative depletion method, the final Harpoon Product (ie, CTC-enriched cell suspension) contains CTCs that express cytokeratin (CK) and EpCAM (canonical CTCs) as well as those with low or no expression of these antigens (non-canonical CTCs). After isolation, CTCs were spun onto microscope slides and imaged using a Vectra Multispectral Imaging System. We obtained performance data on an initial prototype Harpoon assay (Harpoon + Vectra [Hrp+Vec]) and compared CTC enumeration between Hrp+Vec and CS using blood samples from 36 breast and prostate cancer patients. From 7.5 mLs of blood, the Hrp+Vec assay recovered 79.0% to 93.5% of canonical EpCAM+/CK+ CTCs recovered by CS. The Hrp+Vec assay also successfully detected non-canonical CTCs (EpCAM-/CK+ or EpCAM+/CK-) in these samples. At the CS clinical cutoff for prognostic value, where ≥5 CTCs is associated with poor prognosis, the Hrp+Vec assay was 97% concordant with CS. Hrp+Vec also detected CTCs in 12.5% (2/16) more patient samples than CS. Finally, a consensus analysis of all Vectra scan results (including both canonical and non-canonical CTCs) demonstrated that the Hrp+Vec assay detected between 90.5% and 108.9% of the number of CTCs as identified by CS. These results indicate that, when compared with CS, the prototype Hrp+Vec assay detected CTCs with similar efficiency and identified more samples as CTC-positive in these breast and prostate cancer patients. Importantly, the Hrp+Vec assay did enrich non-canonical CTCs thought to be missed by CS, and ongoing efforts are aimed to further characterize these cell populations. Citation Format: Mark Connelly, David Chianese, Carrie Morano, Thai Bui, Shemeeakah Powell, Noel Ngoubilly, Renouard Sanders, Tom Barber, Ravi Kapur, Shyamala Maheswaran, Mehmet Toner, Daniel Haber. Isolation and characterization of circulating tumor cells (CTCs) in breast and prostate cancer: Comparison of Harpoon CTC assay performance with the CellSearch CTC Test. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 4955.
Synthesis, Fluorescence, and Two‐Photon Absorption of Bidentate Phosphane Oxide Derivatives: Complexation with Pb2+ and Cd2+ Cations (2008)

A series of fluorescent phosphane oxide derivatives based on diphenylphosphanoethane (DPPE) and diphenylphosphanomethane (DPPM) skeletons has been prepared by means of Grignard reactions and Sonogashira cross-couplings. The photophysical properties and the linear and nonlinear spectra of these compounds have been investigated. An edge-to-face conformation resulting in the formation of an excimer was confirmed by fluorescence lifetime measurements of these multichromophoric derivatives. Upon complexation with heavy metal ions such as Pb2+ and Cd2+, a red shift of the one- and two-photon excitation spectra was observed in the absorption and emission spectra. Furthermore, enhancement of the electron-withdrawing character of the phosphane oxide resulted in a significant enhancement of the two-photon absorption cross-section, leading to the first biphotonic Cd2+ sensors combining high affinity for Cd2+, large two-photon absorption cross-sections, and significant enhancement of the two-photon excited fluorescence in the presence of the cation. Such derivatives are highly promising for incorporation into devices for the detection of heavy metal ions in water and effluents.
Diagnosis Tool for Motor Condition Monitoring (2005)

In the modern industrial environment there is increasing demand for automatic condition monitoring. With reliable condition monitoring, faults such as mechanical motor failures could be identified in their early stages and further damage to the system could be prevented. Successful monitoring is a complex and application-specific problem, but a generic tool would be useful in preliminary analysis of new signals and in verification of known theories. A generic condition diagnosis tool is introduced in this paper. The tool is based on discriminative energy functions which reveal discriminative frequency-domain regions where failures can be identified. The tool was applied to induction motor bearing fault detection and succeeded in finding characteristic frequencies which allow accurate detection of bearing faults.
Nanoscale Ionic Aggregates in Ionomer Melts. (2017)

Abstract not provided.
Generality-a low cost approach to digital image processing (1993)

The growing market for multimedia and computer vision applications has generated a great deal of commercial interest in video signal processing solutions. Current approaches use dedicated ASICs or large arrays of high performance DSPs such as the TMS320C40. The authors propose a video signal processor, VSP, targetted to accelerate primitive operations commonly encountered in image processing. Recent devices have been implemented which are extensions of DSP architectures or heavily optimised for image coding. The authors target to a broader range of functionality and emphasise performance through parallelism rather than clock speed. This naturally leads to low power devices suitable for portable applications where the authors anticipate the largest application base will be. A general purpose device can dramatically reduce system hardware development costs and enables rapid prototyping, resulting in lower cost products at all the highest volumes. The move from DSP to VSP places considerably greater demands on a silicon architecture-computational requirements are frequently measured in GOPS rather than MOPS. This paper outlines preliminary work carried out in developing a very high performance general-purpose VSP capable of performing a wide range of algorithms.
Contribution des responsables des Cancéropôles au Forum/Débat sur le bilan des actions des Cancéropôles (2014)

The authors, all in charge of the administration of one of the 7 French Cancéropôles, reply to the article authored by Audrey Vézian, and -provide an alternative and more supportive view of the initiatives -sponsored by these regional cancer research networks.
On modeling MPEG video traffics (2002)

This paper traces the development/evolution of three of our previously proposed MPEG coded video traffic models, that can capture the statistical properties of MPEG video data. The basic ideas behind these models are to decompose an MPEG compressed video sequence into several parts according to motion/scene complexity or data structure. Each part is described by a self-similar process. These different self-similar processes are then combined to form the respective models. In addition, Beta distribution is used to characterize the marginal cumulative distribution (CDF) of the self-similar processes. Comparison among the three models shows that the latest model (called the simple IPB composite model) is the most practical one in terms of accuracy and complexity. Simulations based on many real MPEG compressed movie sequences, including StarWars, have demonstrated that the simple model can capture the autocorrelation function (ACF) and the marginal CDF very closely.
Effect of taxol from Pestalotiopsis mangiferae on A549 cells-In vitro study. (2009)

Pestalotiopsis mangiferae Coelomycete fungi were used to examine the production of taxol. The taxol isolated from this fungus is biologically active against cancer cell lines were investigated for its antiproliferative activity in human Non Small Cell Lung Cancer A549 cells. The results showed that the methylene chloride extraction of Pestalotiopsis mangiferae inhibited the proliferation of A 549 cells as measured by MTT and Trypan blue assay. Flow cytometric analysis showed that methylene chloride extraction of Pestalotiopsis mangiferae blocked cell cycle progression in G0/G1 phase. In addition fungal taxol induced A549 cell apoptosis as determined by propidium iodide staining. Further the percentage of LDH release was increased at increasing concentrations which is a measure of cell death. The levels of sialic acid levels and DNA, RNA and protein levels were decreased after treatment with methylene chloride extraction of Pestalotiopsis mangiferae. We suggests that methylene chloride extraction of Pestalotiopsis mangiferae might be considered for future therapeutic application with further studies against lung cancer.
The Ada compiler validation capability (1980)

The Ada Compiler Validation Capability consists of tests, tools, procedures, and documentation designed to enforce (and encourage) development of compilers that conform to the Ada language Standard. In this paper, we discuss our approach to solving the principal problems faced in developing and using such a capability.
Lung Nodule Malignancy Prediction in Sequential CT Scans: Summary of ISBI 2018 Challenge (2021)

Lung cancer is by far the leading cause of cancer death in the US. Recent studies have demonstrated the effectiveness of screening using low dose CT (LDCT) in reducing lung cancer related mortality. While lung nodules are detected with a high rate of sensitivity, this exam has a low specificity rate and it is still difficult to separate benign and malignant lesions. The ISBI 2018 Lung Nodule Malignancy Prediction Challenge, developed by a team from the Quantitative Imaging Network of the National Cancer Institute, was focused on the prediction of lung nodule malignancy from two sequential LDCT screening exams using automated (non-manual) algorithms. We curated a cohort of 100 subjects who participated in the National Lung Screening Trial and had established pathological diagnoses. Data from 30 subjects were randomly selected for training and the remaining was used for testing. Participants were evaluated based on the area under the receiver operating characteristic curve (AUC) of nodule-wise malignancy scores generated by their algorithms on the test set. The challenge had 17 participants, with 11 teams submitting reports with method description, mandated by the challenge rules. Participants used quantitative methods, resulting in a reporting test AUC ranging from 0.698 to 0.913. The top five contestants used deep learning approaches, reporting an AUC between 0.87 - 0.91. The team's predictor did not achieve significant differences from each other nor from a volume change estimate (p =.05 with Bonferroni-Holm's correction).
High-surface-area hydrated lime for SO2 control (1993)

Since 1986, the Illinois State Geological Survey (ISGS), has been developing a process to produce high-surface-area hydrated lime (HSAHL) with more activity for adsorbing SO2 than commercially available hydrated lime. HSAHL prepared by the ISGS method as considerably higher surface area and porosity, and smaller mean particle diameter and crystallite size than commercial hydrated lime. The process has been optimized in a batch, bench-scale reactor and has been scaled-up to a 20--100 lb/hr process optimization unit (POU). Experiments have been conducted to optimize the ISGS hydration process and identify key parameters influencing hydrate properties for SO2 capture (surface area, porosity, particle size, and crystallite size). The known how is available to tailor properties of hydrated limes for specific SO2 removal applications. Pilot-scale tests conducted with the HSAHL under conditions typical of burning high-sulfur coals have achieved up to 90% SO2 capture in various DSI systems. The removal results are enough to bring most high-sulfur coals into compliance with acid rain legislation goals for the year 2000. The focus of the POU program is to generate critical engineering data necessary for the private sector to scale-up the process to a commercial level and provide estimates of the optimal cost of constructionmore » and operation of a commercial plant. ISGS is currently participating in a clean coal technology program (CCT-1) by providing 50 tons of HSAHL for a demonstration test at Illinois Power's Hennepin station in January 1993.« less
Improving Google’s BBR for Reduced Latency and Increased Fairness (2019)

BBR is a low latency congestion control algorithm developed by Google as an alternative to the traditional lossbased TCP (Transmission Control Protocol) algorithms, such as CUBIC. However, recent work shows that BBR suffers from 1) additional queuing delay due to competing flows and 2) poor fairness among flows with different Round Trip Times (RTTs). In this paper, we derive an analytic model for BBR’s Multiplicative Increase/Multiplicative Decrease (MIMD) sending rate control that reveals the origin of these issues. Inspired by Google’s recent patch for reducing queuing delay, we further improve BBR for lower latency. Moreover, our analysis suggests that applying a RTT-based adaptive pacing gain to probe bandwidth helps mitigating the fairness issue. Finally, we validate these improvements through simulations using the ns-3 network simulator.
Assessment of residual bulky tumor using FDG-PET in patients with advanced stages after completion of chemotherapy. Final report of the GHSG HD15 trial (2012)

Ziele: The role of additional radiotherapy after chemotherapy for advanced-stage Hodgkin lymphoma (HL) is unclear. The German Hodgkin Study Group (GHSG) thus performed the HD15 trial in which advanced-stage HL patients having residual disease after 6–8 cycles of BEACOPP were evaluated by 18F-FDG-PET following chemotherapy. Methode: Entry criteria for the PET question in HD15 were partial remission after the end of chemotherapy with at least one involved nodal site measuring more than 2.5cm in diameter by CT. A total of 2182 patients with de novo HL were included in HD15 of whom 740 wee qualified for the PET question. An expert panel performed the assessment of response and PET. The negative-predictive value (NPV) of PET was defined as the proportion of patients without progression or relapse within 12 months. Ergebnis: The full analysis set included 740 patients of whom 712 had at least 12 months of follow-up. 74% were PET-negative and 26% PET-positive. In the PET-negative group, a total of 31 patients relapsed or had radiotherapy resulting in a negative prognostic value of 94%. Overall, only 12% of patients had additional radiotherapy as compared to 70% in our prior HD9 trial. In addition, there was no difference in PFS or overall survival as compared to our earlier trials in advanced-stage HL. Schlussfolgerung: The NPV of PET of 94% suggests that indeed only patients with residual disease after chemotherapy who are PET-positive need additional radiotherapy. PET-negative patients at least after BEACOPP can be spared from additional radiotherapy.
A systematic algorithm for the design of multiplierless FIR filters (2002)

A systematic algorithm is proposed for designing multiplierless finite-impulse response (FIR) filters. This algorithm minimizes the number of adders required to implement the overall filter to meet the given amplitude criteria. The optimization is performed in two basic steps. First, a linear programming algorithm is used for determining a parameter space of the infinite-precision coefficients including the feasible space where the filter meets the given amplitude specifications. The second step involves finding the filter parameters in this space such that the resulting filter meets the given criteria with the simplest coefficient representation forms. The efficiency of the proposed algorithm is illustrated by means of several examples taken from the literature.
<title>Organic electroluminescent devices with polymeric materials</title> (1993)

Electroluminescent devices with double organic layers were fabricated using polymeric materials as the hole transport layer and tris(8-quinolinolato)aluminum(III) complex (Alq) as the emitting layer, respectively. The polymeric materials used are poly(methylphenylsilane), plasma-polymerized carbon disulfide, and polycarbonate (TPD). A cell structure of glass substrate/indium-tin-oxide (ITO)/polymer layer/Alq/Mg:Ag (10:1) or Mg/Ag was employed. Among the polymeric systems, the doped PC system affords efficient electroluminescence from the Alq layer. In this cell, bright green emission with luminance of 7,700 cd/m<SUP>2</SUP> was observed at a drive voltage of 16 V. Single-layer-type EL devices were also fabricated using poly(methyl methacrylate) (PMMA) molecularly doped with both TPD and Alq. A cell structure of glass substrate/ITO/doped PMMA/Mg:Ag (10:1) was employed. Green emission with luminance of 920 cd/m<SUP>2</SUP> was achieved for a cell with a TPD/Alq ratio of 0.67 at a drive voltage of 17 V, and the EL color was tuned to blue-green and yellow-orange by further doping the PMMA layer with suitable organic dyes.