gebhart/patrepeval huggingface dataset:
Learning Modulation Design for SWIPT with Nonlinear Energy Harvester: Large and Small Signal Power Regimes (2019)

Nonlinear energy harvesters (EH) behave differently depending on the range of their input power. In the literature, different models have been proposed mainly for relatively small and large input power regimes of an EH. Due to the complexity of the proposed nonlinear models, obtaining analytical optimal or well performing signal designs have been extremely challenging. Relying on the proposed models in the literature, the learning problem of modulation design for simultaneous wireless information-power transfer (SWIPT) over a point-to-point link is studied. Joint optimization of the transmitter and the receiver is implemented using neural network (NN)-based autoencoders. The results reveal that for relatively small channel input powers, as the power demand increases at the receiver, one of the symbols is shot away from the origin while the remaining symbols approach zero amplitude. In the very extreme case of merely receiver power demand, the modulations are in the form of On-Off keying signalling with a low probability of the On signal. On the other side, for relatively large channel input powers, it is observed that as the receiver power demand increases, a number of symbols approach zero amplitude, whereas the others (more than one symbol) get equally high amplitudes but with different phases. In the extreme scenario of merely receiver power demand, the modulation resembles multiple On-Off keying signalling with different phases.
919-P: Canada Real-World Analysis of Flash Glucose Monitoring and Impact on Time-in-Range and Hypoglycemia (2019)

Prior analyses of global data from real world use of flash glucose monitoring have associated frequency of scanning with greater time in range and lower mean glucose, glucose variability, and hypoglycemia. These analyses did not include data from North America as flash glucose monitoring became available in late 2017. The objective of this follow-up analysis is to focus on real world outcomes in patients using flash glucose monitoring in Canada. A server collected anonymized data from patients whose flash glucose readers are uploaded (by patient or health care professional). Data from patients within Canada was analyzed through September 2018 (approximately 1 year). To understand the relationship between time in range and glucose variability with monitoring frequency, individuals were divided into 10 equal sized groups based on scanning frequency. Average ± SE time in range (glucose 70 mg/dL - 180 mg/dL [3.9 mmol/L - 10.0 mmol/L]) and time in glucose ≤ 54 mg/dL (∼3.0 mmol/L) was calculated for each group. This analysis includes 15,424 readers, 95,103 sensors, and 108 million glucose measurements with an average of 12 scans per day. Patients in the lowest scanning frequency decile (3.7 scans per day) spent 12.6 ± 0.14 hours in range and 28.8 ± 1.2 minutes with a glucose ≤ 54 mg/dL. Patients in the highest scanning frequency decile (29.2 scans per day) spent 16.6 ± 0.12 hours in range and 22.1 ± 1.0 minutes with a glucose ≤ 54 mg/dL. Real-world data from Canada demonstrates that higher frequency of scanning is associated with increased time in range and decreased hypoglycemia. This analysis is consistent with prior analyses and suggests that patients with diabetes who scan to obtain their glucose more frequently derive greater benefit than patients who scan less frequently. Disclosure L. Berard: Advisory Panel; Self; Eli Lilly and Company. Consultant; Self; Abbott, Ascensia Diabetes Care, AstraZeneca, Bayer AG, Becton, Dickinson and Company, Janssen Pharmaceuticals, Inc., LifeScan Canada, Mylan, Novo Nordisk Inc., Sanofi. Research Support; Self; Montmed Inc. Speaker's Bureau; Self; Boehringer Ingelheim Pharmaceuticals, Inc., Merck &amp; Co., Inc. N. Virdi: Employee; Self; Abbott, Proteus Digital Health. Stock/Shareholder; Self; Johnson &amp; Johnson. T. Dunn: Employee; Self; Abbott Laboratories.
The vibrational spectra of Al2Br6, Al2I6, Ga2Br6, Ga2I6, and In2I6 (1968)

The Raman and i.r. spectra of the title compounds are recorded in various phases. Using helium–neon laser excitation the Raman spectra of intensely coloured melts of Ga2I6 and In2I6 are recorded. Vibrational assignments are made for all compounds using a normal-co-ordinate treatment identical to that used previously for Ga2CI6.
Right Ventricular Outflow Tract Stenting in Tetralogy of Fallot Infants With Risk Factors for Early Primary Repair (2016)

Right ventricular outflow tract stenting of symptomatic tetralogy of Fallot with poor anatomy (small pulmonary arteries) and adverse factors (multiple comorbidities, low weight) relieves cyanosis and defers surgical repair. This allowed pulmonary arterial and somatic growth with clinical results comparable to early surgical repair in more favorable patients.
Fabrication of Highly Ordered Multilayer Films Using a Spin Self-Assembly Method (2001)

A very short processing time for making well-organized multilayer films can be achieved employing the novel spin self-assembly method described in this paper. The authors elaborate on the advantages of this method versus conventional self-assembly methods for the fabrication of multilayer polyelectrolyte films. The Figure illustrates that the spinning process (bottom) yields far better organized layers than for instance the direct dipping method (top).
Relevance of a Feed-Forward Model of Visual Attention for Goal-Oriented and Free-Viewing Tasks (2010)

A purely bottom-up model of visual attention is proposed and compared to five state-of-the-art models. The role of the low-level visual features is examined in two contexts. Two datasets are used: one containing data coming from an eye tracking experiment obtained in a free-viewing task and a second containing 5000 hand-label pictures (observers had to enclose the most visually interesting objects in a rectangle). The relevancy of the bottom-up models, i.e. the ability of a model to predict where the salient areas are located, is evaluated. Whatever the metrics and the datasets, the degree of similarity between predictions and ground truth is significantly above chance. The proposed model, resting on a small number of features, is shown to be a good predictor of the human visual fixations but also a good predictor of the objects chosen as interesting by observers. This study suggests that the low-level of visual features have a significant role in a free-viewing task but also in a high-level visual task, such as the choice of the object of interest in a complex visual scene. Another outcome concerns the viewing duration used in eye tracking experiments. Results suggest that this parameter is finally not as critical as one would expect.
A Shared-Aperture Tracking Display for Augmented Reality (2003)

The operation and performance of a six degree-of-freedom (DOF) shared-aperture tracking system with image overlay is described. This unique tracking technology shares the same aperture or scanned optical beam with the visual display, virtual retinal display (VRD). This display technology provides high brightness in an AR helmet-mounted display, especially in the extreme environment of a military cockpit. The VRD generates an image by optically scanning visible light directly to the viewer's eye. By scanning both visible and infrared light, the head-worn display can be directly coupled to a head-tracking system. As a result, the proposed tracking system requires minimal calibration between the user's viewpoint and the tracker's viewpoint. This paper demonstrates that the proposed shared-aperture tracking system produces high accuracy and computational efficiency. The current proof-of-concept system has a precision of +/− 0.05 and +/− 0.01 deg. in the horizontal and vertical axes, respectively. The static registration error was measured to be 0.08 +/− 0.04 and 0.03 +/− 0.02 deg. for the horizontal and vertical axes, respectively. The dynamic registration error or the system latency was measured to be within 16.67 ms, equivalent to our display refresh rate of 60 Hz. In all testing, the VRD was fixed and the calibrated motion of a robot arm was tracked. By moving the robot arm within a restricted volume, this real-time shared-aperture method of tracking was extended to six-DOF measurements. Future AR applications of our shared-aperture tracking and display system will be highly accurate head tracking when the VRD is helmet mounted and worn within an enclosed space, such as an aircraft cockpit.
Acute kidney injury in patients with sepsis: a contemporary analysis (2008)

AKIN criteria are a useful tool to characterize and stratify septic patients according to the risk of death.
Letter by Palazzuoli et al Regarding Article, “Is Worsening Renal Function an Ominous Prognostic Sign in Patients With Acute Heart Failure? The Role of Congestion and Its Interaction With Renal Function” (2012)

FIGURES 14–15. External view of left pedipalp chela. 14. Holotype female of Alacran chamuco, sp. nov. 15. Adult female Alacran tartarus Francke (scale = 1mm).
Cellular Microbiology Emerging (1996)

Microbial pathogens have evolved to interfere with essential processes in eukaryotic cells. P. Cossart illustrates how a new field, cellular microbiology, is emerging in which the targets of these microbes are being identified and many aspects of normal cell biology are being revealed.
Peptide conjugates for chromosomal gene targeting by triplex-forming oligonucleotides (2004)

Triplex-forming oligonucleotides (TFOs) are DNA-binding molecules, which offer the potential to selectively modulate gene expression. However, the biological activity of TFOs as potential antigene compounds has been limited by cellular uptake. Here, we investigate the effect of cell-penetrating peptides on the biological activity of TFOs as measured in an assay for gene-targeted mutagenesis. Using the transport peptide derived from the third helix of the homeodomain of antennapedia (Antp), we tested TFO-peptide conjugates compared with unmodified TFOs. TFOs covalently linked to Antp resulted in a 20-fold increase in mutation frequency when compared with 'naked' oligonucleotides. There was no increase above background in mutation frequency when Antp by itself was added to the cells or when Antp was linked to mixed or scrambled sequence control oligonucleotides. In addition, the TFO-peptide conjugates increased the mutation frequency of the target gene, and not the control gene, in a dose-responsive manner. Confocal microscopy using labeled oligonucleotides indicated increased cellular uptake of TFOs when linked to Antp, consistent with the gene-targeting data. These results suggest that peptide conjugation may enhance intranuclear delivery of reagents designed to bind to chromosomal DNA.
Structure of Shiga Toxin Type 2 (Stx2) from Escherichia coli O157:H7 (2004)

Several serotypes of Escherichia coli produce protein toxins closely related to Shiga toxin (Stx) from Shigella dysenteriae serotype 1. These Stx-producing E. coli cause outbreaks of hemorrhagic colitis and hemolytic uremic syndrome in humans, with the latter being more likely if the E. coli produce Stx2 than if they only produce Stx1. To investigate the differences among the Stxs, which are all AB(5) toxins, the crystal structure of Stx2 from E. coli O157:H7 was determined at 1.8-A resolution and compared with the known structure of Stx. Our major finding was that, in contrast to Stx, the active site of the A-subunit of Stx2 is accessible in the holotoxin, and a molecule of formic acid and a water molecule mimic the binding of the adenine base of the substrate. Further, the A-subunit adopts a different orientation with respect to the B-subunits in Stx2 than in Stx, due to interactions between the carboxyl termini of the B-subunits and neighboring regions of the A-subunit. Of the three types of receptor-binding sites in the B-pentamer, one has a different conformation in Stx2 than in Stx, and the carboxyl terminus of the A-subunit binds at another. Any of these structural differences might result in different mechanisms of action of the two toxins and the development of hemolytic uremic syndrome upon exposure to Stx2.
UV/heat dual‐curable adhesive tapes for fabricating stacked packages of semiconductors (2008)

Abstract To facilitate the fabrication of a reliable stacked package for a semiconductor, UV/heat dual curing of adhesives was investigated. The formulated adhesives contained acrylic monomer and epoxy resins. First, UV curing was conducted on the acrylic monomer, followed by heat curing. It was found that UV‐curable acrylic monomers affected the adhesive's properties, e.g., adhesion, water absorption, and viscoelasticity. As the acrylic monomer, neopentylglycol diacrylate (NPGDA), trimethylolpropane triacrylate (TMPTA), dipentaerythritol hexaacrylate (DPHA), and tricyclodecanedimethanol acrylate (TCDDA) were used to investigate the effect of functional group numbers and structure. As a result, an acrylic monomer that has two functional groups with a rigid moiety (TCDDA) showed acceptable properties as adhesives for the fabrication, and thus a UV/heat‐curing adhesive has been successfully developed. © 2008 Wiley Periodicals, Inc. J Appl Polym Sci, 2008
Fugitive Interface Coating in Oxide-Oxide Composites: A Viability Study (2008)

Sapphire filament/alkoxy-derived YAG matrix composites with fugitive carbon interface layers (via CVD coating) were fabricated by hot pressing. It was reasoned that following oxidation of the carbon layer, sufficient mechanical interlocking would remain for load transfer, and the resulting void layer would maintain sufficiently weak interfaces for toughening. Filament push-out tests were performed to assess the interfacical shear strengths for various composite conditions (with and without carbon layer, oxidized, and long-term heat-treated). The average shear strength varied from 2.1 to 84.7 MPa for the as-hot pressed composite with a carbon interface coating. The filaments in the composite without carbon coating could not be pushed out and, based on the maximum load applied, the average shear strength was calculated to be more than 200 MPa. After the oxidation of the carbon coating layer in the composite, the measured average shear strengths were 10.4 and 13 MPa. The same composite was heat treated at 1500°C for 60 h in air and the average shear strength varied from 1.8 to 27.6 MPa. The microstructure of the heat-treated composite did not change from the as-processed condition, and this result implies the morphological stability of the sapphire/YAG composite at high temperatures.
Collision prediction and avoidance amidst moving objects for trajectory planning applications (2002)

A methodology for computing a collision-free trajectory for mobile robots amidst moving objects is presented. This planner is based on a technique for computing the minimum translational distance between two mobile objects. This distance is then used for predicting and avoiding a collision. The computation of this distance is based on the application of the GJK algorithm to a particular subset of the Minkowski difference set of the involved objects. This subset states the separation or penetration distance between two objects along their given motions. When a collision is predicted, a collision-free intermediate temporal-position is generated avoiding such a collision.
Disruption of protein–protein interactions: design of a synthetic receptor that blocks the binding of cytochrome c to cytochrome c peroxidase (2001)

Synthetic receptor 1 has been found via fluorescence titration to compete effectively with cytochrome c peroxidase for binding cytochrome c (Cc), forming 1:1 Cc:1 complex with a binding constant of (3 +/- 1) x 10(8) M-1, and to disrupt Cc: Apaf-1 complex, a key adduct in apoptosis.
New developments in vector velocity imaging using the transverse oscillation approach (2013)

Vector velocity imaging using the Transverse Oscillation (TO) approach has recently been FDA approved for linear array transducers on a commercial platform. It can now be used clinically for studying the complex ow at e.g. bifurcations, valves, and the heart in real time. Several clinical examples from venous ow to rotational ow in the heart will be shown. The technique is also being further developed and adapted for convex and phased array probes, for spectral velocity estimation, pressure estimation, and for three dimensional velocity tensor imaging. It is shown how the methods are optimized using Field II simulations along with several examples of their performance.
The yeast acid phosphatase can enter the secretory pathway without its N-terminal signal sequence. (1987)

The repressible Saccharomyces cerevisiae acid phosphatase (APase) coded by the PHO5 gene is a cell wall glycoprotein that follows the yeast secretory pathway. We used in vitro mutagenesis to construct a deletion (delta SP) including the entire signal sequence and four amino acids of the mature sequence of APase. An APase-deficient yeast strain was transformed with a high-copy-number plasmid carrying the PHO5/delta SP gene. When expressed in vivo, the PHO5/delta SP gene product accumulated predominantly as an inactive, unglycosylated form located inside the cell. A large part of this unglycosylated precursor underwent proteolytic degradation, but up to 30% of it was translocated, core glycosylated, and matured by the addition of mannose residues, before reaching the cell wall. It appears, therefore, that the signal sequence is important for efficient translocation and core glycosylation of yeast APase but that it is not absolutely necessary for entry of the protein into the yeast secretory pathway. mRNA obtained by in vitro transcription of PHO5 and PHO5/delta SP genes were translated in vitro in the presence of either reticulocyte lysate and dog pancreatic microsomes or yeast lysate and yeast microsomes. The PHO5 gene product was translocated and core glycosylated in the heterologous system and less efficiently in the homologous system. We were not able to detect any translocation or glycosylation of PHO5/delta SP gene product in the heterologous system, but a very small amount of core suppression of glycosylated material could be evidenced in the homologous system.
Contact angle measurement for hydrogen/brine/sandstone system using captive-bubble method relevant for underground hydrogen storage (2021)

Subsurface porous formations provide large capacities for underground hydrogen storage (UHS). Successful utilization of these porous reservoirs for UHS depends on accurate quantification of the hydrogen transport characteristics at continuum (macro) scale, specially in contact with other reservoir fluids. Relative-permeability and capillary-pressure curves are among the macro-scale transport characteristics which play crucial roles in quantification of the storage capacity and efficiency. For a given rock sample, these functions can be determined if pore-scale (micro-scale) surface properties, specially contact angles, are known. For hydrogen/brine/rock system, these properties are yet to a large extent unknown. In this study, we characterize the contact angles of hydrogen in contact with brine and Bentheimer and Berea sandstones at various pressure, temperature, and brine salinity using captive-bubble method. The experiments are conducted close to the in-situ conditions, which resulted in water-wet intrinsic contact angles, about 25 to 45 degrees. Moreover, no meaningful correlation was found with changing tested parameters. We monitor the bubbles over time and report the average contact angles with their minimum and maximum variations. Given rock pore structures, using the contact angles reported in this study, one can define relative-permeability and capillary-pressure functions for reservoir-scale simulations and storage optimization.
Imagining History (1996)

Veronica Marie Gregg, Jean Rhys's Historical Imagination: Reading and Writing the Creole. Chapel Hill and London: The University of North Carolina Press, 1995, 228 pgs.
Abstract TMP44: Personalizing Rehabilitation for Stroke Survivors- A Big Data Approach (2017)

Introduction: Advances in connected health delivery provides a unique opportunity to maximize intervention effectiveness for stroke patients. It has also helped collect large sets of data to facilitate clinical decision making. This vastly insightful data is used to personalize neurorehabilitation where the evidence for gains in chronic stroke patients is weak. Methods: Over a span of 2 years (2013-2015), data was anonymously aggregated and analyzed from over 2,500 patients with post-stroke aphasia. Data was collected using a mobile therapy platform, Constant Therapy, which has 60 evidenced-based language and cognitive therapy tasks. The program was used by patients in the home and clinic under the guidance of a clinician, or under their own volition if not regularly seeing a clinician. This program dynamically adapted to each patient’s progress. Patients who completed between 3 and 1000 treatment sessions were analyzed to determine which tasks showed statistically significant changes. These data were compared with control patients who completed tests at two separate time points but with no intervening treatment. Results: Despite the older demographic of patients (median age = 64 yrs), they performed an average of over 20 minutes on home therapy every day. The analyses take into account the number of patients who completed a specific task and show a significant change (all p &lt;.05) for accuracy or latency. For example, the 2-step Auditory Command task (which requires a user to follow 2-step directions) showed a 12 point gain in accuracy and 39% improvement in processing speed in 1,200 patients. The results also show that patients with higher initial severity scores showed significant gains in accuracy, and reach similar post-treatment accuracy to those with lower severity scores, provided that they received an appropriate dosage of therapy. In contrast, control patients showed minimal gains on tasks that were assigned. Conclusion: These results show that all patients, including the most severe, can make progress in their rehabilitation when treatment is individualized for them. Analysis of large data sets can be used to inform rehabilitation by highlighting therapies that are effective while accounting for etiology and individual variability.