gebhart/patrepeval huggingface dataset:
Leukotoxin kills rodent WBC by targeting leukocyte function associated antigen 1. (2013)

Leukotoxin is a protein that is secreted by Aggregatibacter actinomycetemcomitans and that primarily targets the active form of leukocyte function associated antigen 1 (LFA1) on WBC. Because of its specificity for WBC, leukotoxin is being developed as a novel biologic treatment for hematologic malignancies and autoimmune-inflammatory diseases. Early studies indicated that leukotoxin is specific for WBC from humans and Old World primates. In the current study, we used in vivo and in vitro assays to show that leukotoxin has a wider host range than previously believed and can kill rodent WBC. Administration of leukotoxin to rats and mice resulted in a rapid drop in WBC number but had no effect on RBC or platelet counts. Using LFA1-knockout mice, we showed that leukotoxin-mediated depletion of WBC is dependent on LFA1. In addition, similar to its effect on human monocytes, leukotoxin kills murine myeloid leukemia via a lysosome-mediated pathway that is dependent on cathepsin D. This newly described broader host range of leukotoxin enables the biology of the protein to be studied in rodent species and offers the possibility of using rodent models for evaluating the therapeutic efficacy of leukotoxin in various diseases.
The design and analysis of pyramidal microstrip antenna for GPS application (2015)

This paper deals with the design and analysis of pyramidal microstrip antenna for GPS application in order to find the direction of arrival of signals. The 4 antenna elements are implemented on inclined walls to reduce coupling between antenna elements. Because of the inclined walls, antenna array is able to have a reduced diameter. Moreover, a monopole auxiliary antenna is added to compensate channel imbalance between the four receivers put behind antennas. Measured coupling balance between channels was within ±1.2dB.
Performance Measures for Comparison of Determining Post Closure Care (PCC) Period in Landfills (2007)

According to solid waste facility regulations codified in 40 CFR Section 258.61(b), the 30-year PCC period specified by Subtitle D can be extended or shortened by the governing regulatory agency on a site-specific basis. Post closure care (PCC) activities under Subtitle D include leachate collection and treatment, ground water monitoring, inspection and maintenance of the final cover, and monitoring to insure that landfill gas does not migrate off site or into on-site buildings. However, quantification of post closure performance of a landfill is difficult since it involves considerations of parameters that include technical factors, environmental considerations, and economic assessment. This paper presents a simple approach for assessing and projecting the performance of landfill components to predict their performance after the landfill is closed. The component performance analysis for landfills (CPALF) is a flexible, knowledge-based approach which can be used to develop strategies to minimize future risks due to component failures and for developing maintenance strategies during the PCC period of landfills.
Manganese Microperoxidase-8 (1998)

Demetalation of Fe(III) microperoxidase-8 (MP8) by anhydrous HF gives metal-free MP8, a convenient starting material for a wide variety of metal-substituted MP8 derivatives, including Mn(III)MP8. Mn(III)MP8 was produced by treatment of metal-free MP8 with manganous acetate in aerated aqueous solution; it was characterized by mass spectrometry and UV−visible absorption spectroscopy. Resonance Raman spectra suggest that Mn(III)MP8 contains histidine and water axial ligands at neutral pH. The Mn(IV)=O derivative is readily prepared by oxidation of Mn(III)MP8 with hydrogen peroxide or Ru(bpy)_3^(3+) (bpy = 2,2‘-bipyridine).
julia: v0.4.0-rc1 (2015)

All major 0.4 changes are in, so here at long last is 0.4-rc1. 0.4 is still open for bug fixes, new development should continue to target master for eventual branching into version 0.5. For source builds in restricted environments (e.g. no network access) use the tarball attached below (julia-0.4.0-rc1_e5c6964a49-full.tar.gz) as it already contains all dependencies pre-downloaded.
ChemInform Abstract: A New Pyrrole Synthesis via Silver(I)‐Catalyzed Cycloaddition of Vinylogous Diazoester and Nitrile. (2013)

Abstract A new synthesis of di‐ and trisubstituted pyrroles is achieved by treating vinylogous diazoesters and readily available nitriles with a catalytic amount of silver(I) antimony hexafluoride.
Abnormal differentiation and hyperproliferation of alveolar cells in a mouse model of lung-specific deletion of the transcription factor C/EBPα (2005)

Proc Amer Assoc Cancer Res, Volume 46, 2005

1050 

The leucine zipper family transcription factor CCAAT enhancer binding protein alpha (C/EBPα) has been implicated in the regulation of proliferation and differentiation and was shown to have tumor suppressor activity in different tissues. We have previously shown that C/EBPα promotes growth arrest and induces differentiation in lung cancer cells, suggesting that C/EBPα might be a novel tumor suppressor in lung cancer. The current study was aimed at understanding the role of C/EBPα in regulating differentiation and proliferation in the respiratory epithelium in vivo. For that purpose, we selectively and conditionally deleted C/EBPα in respiratory epithelial cells in the mouse lung utilizing doxycycline-inducible Cre-driven excision. Mice undergoing C/EBPα excision during development died perinatally due to respiratory failure, indicating that C/EBPα is required for the transition to air breathing at birth. Southern Blot analysis showed that excision of the C/EBPα gene was lung-specific and occurred with an efficiency of 60-80%. Real-time PCR analysis confirmed that C/EBPα mRNA expression was reduced by 50%. Immunostaining, on the other hand, showed an almost complete loss of C/EBPα protein. The lungs displayed markedly abnormal pathology, characterized by loss of airspace due to hyperproliferation of alveolar cells. In addition, the alveolar cells showed features of a block in terminal maturation, characterized by absence of fibrolamellar bodies and continued presence of glycogen-rich inclusions, as assessed by electron microscopy and Periodic Acid Schiff staining. Expression profiling is ongoing to understand the molecular events underlying these findings. Experiments with postnatal excision of C/EBPα are also underway to evaluate whether its loss at later stages can predispose mice to lung cancer. However, since the transgenic approach utilized allows for leaky excision of the C/EBPα gene late in development, we analyzed a group of untreated mice at age 2 months. Of 4 mice, one displayed regions of abnormal lung pathology comprising about 5% of the epithelial surface, characterized by nodular areas with increased cell density and loss of airspace. Interestingly these abnormal areas also displayed loss of C/EBPα expression. These results corroborate the hypothesis that C/EBPα is an important regulator of differentiation and proliferation in the airway epithelium and suggests that loss of C/EBPα could be an important event in the multi-step process of lung tumorigenesis.
Electrochemical Performance of BaSnO3Anode Material for Lithium-Ion Battery Prepared by Molten Salt Method (2016)

Perovskite-like structure BaSnO3 ceramic oxide has been prepared by low temperature molten salt method using KOH as a flux and Ba(OH)2 and BaCl2 as precursors. The as-prepared compounds were characterized by various techniques such as X-Ray Diffraction (XRD), Scanning Electron Microscope (SEM), Brunauer-Emmett-Teller (BET) and X-ray photoelectron spectroscopy (XPS). The electrochemical performance of the compounds has been evaluated by galvanostatic cycling (GC) and cyclic voltammetry (CV). GC results exhibit stable and good reversible capacity retention of 80% after 50 cycles, in the voltage range of 0.005–1.0 V vs. Li, at a constant current density of 60 mA g−1. In contrast, at higher voltage (0.005–3.0 V), we observed higher reversible capacity during the initial cycles, albeit the more capacity fading after few cycles. Interestingly, the compounds showed excellent coulombic efficiencies of 99% when cycled at 0.005–1.0 V.
Les expérimentations in situ : principes et perspectives (2010)

Identifier l&#8217;origine d&#8217;une perturbation, discriminer un stress physique ou chimique, et quantifier les liens de cause &#224; effet des pollutions supposent de recueillir des donn&#233;es n&#233;cessaires &#224; l&#8217;&#233;valuation de la qualit&#233; des eaux. &#192; l&#8217;heure actuelle, la majorit&#233; des donn&#233;es est issue de tests de laboratoire, obtenue dans un cadre tr&#232;s contr&#244;l&#233;. Les donn&#233;es recueillies dans les conditions naturelles sont tr&#232;s parcellaires et encore peu r&#233;pandues m&#234;me si leur d&#233;veloppement serait extr&#234;mement utile. Quels sont les principes de ces exp&#233;rimentations in situ, leur int&#233;r&#234;t, dans quelle mesure peuvent-elles &#234;tre d&#233;ploy&#233;es &#224; une large &#233;chelle&#160;? Les auteurs font le point sur ces questions.
Precision Synthesis of Subnanoparticles Using Dendrimers as a Superatom Synthesizer (2014)

Classical metal-based nanomaterials come in two prominent types: a mononuclear or multinuclear complex chemically stabilized by organic ligands or a nanoparticle (also called a nanorod, nanosheet, or nanocrystal) physically stabilized by inorganic or polymer supports. Over the last decade, a class of superatoms that lies between these categories of materials has attracted attention because their properties are dramatically different from those typically ascribed to their component elements. Typically the superatoms include a specific, low number of metallic atoms. Because a one-atom difference can alter the properties of these superatoms, their synthesis must be ultraprecise, requiring one-atom resolution. To date, researchers have only been able to prepare monodisperse superatoms using gas-phase synthesis followed by purification through a flight tube. Though this technique provides monodisperse superatoms, it does not allow researchers to produce them in large quantites. Other researchers have proposed ligand-assisted liquid-phase synthesis as an alternative, but this technique is only useful for a few stable "magic number" clusters. Recently researchers have developed a new approach for the synthesis of superatoms that employs a novel class of molecular templates, which can define the number of metal ions or salts precisely. As a result, researchers can now synthesize nanoparticles or even subnanoparticles successfully. A dendrimer-type template has proven to be especially useful for ultraprecise control of the atomicity of the product, but it works with a full range of metal elements. In this Account, we highlight recent advances in the precise preparation of metal-assembling complexes using the dendrimer as a template. Next we discuss the selective assembly of subnanoparticles that utilize the dendrimer as a superatom synthesizer. The resulting subnanoparticles are almost monodisperse, and as a result, some of them exhibited distinctive characteristics based on their atomicity. For example, because of the quantum-size effect, the reduction in particle size of TiO2 and other metal-oxide subnanoparticles led to a significant shift in the band-gap energy. In addition, a miniaturized platinum particle less than 1 nm in diameter showed unexpectedly high catalytic activity for the oxygen reduction reaction (ORR) and other related reactions. Of particular note, in all these examples, this substantial change in their properties arose out of a single-atom difference in the atomicity. These results suggest that next-generation subnanoparticle design could play an important role in new materials and offer an additional palette of physical and chemical properties for new applications.
25.2: Eye‐Tracking Solutions for Real‐Time Holographic 3‐D Display (2008)

Abstract The SeeReal electro‐holographic display approach — using an observer window — has for the first time made possible large volume holographic reconstruction with real‐time calculation. The observer tracking solution as implemented in the first SeeReal prototype is compared to new concepts providing for a larger tracking angle.
The Virtualized Virtual Machine: The Next Generation of Virtual Machine Technology (2004)

Virtual machine technology will continue to increase in importance, eventually spanning from motes to supercomputers. In this position paper, I describe my personal vision for the virtual machine of the future: a virtual machine that dynamically modifies all portions of itself, rather than just the compiled code, and that dynamically reconfigures the underlying hardware as well. 1.
Assessment on Marginal Trace Element Status (2002)

A review with 20 references is given on the research progress of the characteristics,advantages and disadvantages of the major methods and markers,which have already been or are likely to be used for assessing the status of zinc,iron and selenium,especially for the marginal status assessment,on the purpose of helping to screen and search for the most sensitive,specific,accurate and reliable markers for nutrition assessment.
Contrast-Enhanced X-ray Detection of Breast Microcalcifications in a Murine Model Using Targeted Gold Nanoparticles (2014)

Microcalcifications are deposits of hydroxyapatite (HA) mineral within breast tissue and the most common abnormality detected by mammography when screening for breast cancer due to exhibiting greater X-ray attenuation than the surrounding tissue. However, the detection of microcalcifications is limited by the sensitivity and specificity of mammography. Therefore, the objective of this study was to investigate in vivo targeted delivery of bisphosphonate-functionalized gold nanoparticles (BP-Au NPs) for contrast-enhanced detection of microcalcifications using computed tomography (CT). A murine model was developed for precise, a priori control over the level of microcalcification burden by injecting varying concentrations of HA crystals in a Matrigel carrier into mammary glands. The measured X-ray attenuation of microcalcifications containing varying HA concentrations demonstrated that the model was reproducible and able to recapitulate varying levels of microcalcification burden, including levels undetectable by CT in the absence of contrast enhancement. After intramammary delivery, BP-Au NPs provided enhanced contrast for the detection of microcalcifications that were otherwise below the CT detection limit. BP-Au NPs targeted microcalcifications due to specific binding to HA crystal surfaces, resulting in contrast between the HA microcalcification site and surrounding tissue which was visibly apparent (∼30-135 HU) within 2 days after delivery. Therefore, targeted BP-Au NPs enabled improved sensitivity and specificity for the detection of microcalcifications.
FRACTURE-DISLOCATION OF THE LUMBOSACRAL SPINE (1992)

This report describes an extensively comminuted fracture of the sacrum and the L-5 vertebral body with complete anterior dislocation of the lumbar spine on the sacrum that occurred in a 19-year-old man ejected from a motor vehicle. Lumbosacral dissociation was characterized by computed tomography with three-dimensional and multiplanar reconstruction, and definitively managed by posterior instrumentation using locking hook spinal rods attached to the pelvis with hockey stick attachments by the Galveston technique. Implications of this case and a review of the literature are presented.
Effects of Mis-Positioning a New Cuffless Blood Pressure Sensor and Optimal Design via a 3D Fluid-Solid-Electric Finite Element Model (2015)

The effects of mis-positioning a newly-designed noninvasive, cuffless blood pressure sensor are thoroughly investigated via simulation and analysis on a 3D fluid-solid-electric finite element model. A subsequent optimal design of this blood pressure is conducted based on the aforementioned mis-positioning effects. A highly-accurate, non-invasive, cuffless blood pressure (BP) sensor was successfully developed recently for an effective personal monitoring device on blood pressures. This new small-sized, portable blood pressure sensor is able to offer continuous BP measurements. The availability of continuous blood pressures are important for monitoring and evaluating personal cardiovascular systems. The sensor contains a strain-sensitive electrode encapsulated by flexible polymer. As the sensor placed on the position right on the top of the center of the wrist pulsation area, the deflection of the sensor induces the resistance changes of the electrode. By measuring the changes in electrode resistance, the level of pulsation is successfully quantified. Subsequent calculation based in this measurement can lead to fair estimates on blood pressures. However, as the sensor is placed on the wrist area where pulsation occurs, the mis-positioning of the sensor to the desired location, the center of the pulsation area, is inevitable. This study is dedicated to investigate the effects of the mis-positioning via a 3D finite element model. A new 3D fluid-solid-electro coupling interaction finite element model of the wrist is built for predicting the vibration of radial artery and then diastolic and systolic blood pressures. The FEM includes sensor of gel capsule and strain-sensing electrodes, radial artery, blood, radius bones, tendon, muscles and the front-end readout circuit. The FEM is the multi physics FEM with fluid, solid and electric. The section of wrist is constructed from magnetic resonance imaging (MRI) and the length of the FEM is 40mm. The complete 3D FEM model successfully simulated the vibration of skin surface and the sensor module. The diastolic and systolic blood pressures can be accurately predicted by the simulated output resistance. The pulsation levels due to varied mis-positionings are simulated by the built model, and simulation results are successfully validated by experiments. It is found that due to the unsymmetrical geometry of the wrist, the pulsation levels are also varied in an un-symmetric fashion with the mis-positionings in different directions. The maximum output of the BP sensor occurs when the sensor is placed ±3 mm away from the center of the pulsation area, while the sensor output remain valid for subsequent signal processing as the sensor is placed within ±5 mm from the pulsation center. Considering the inevitable mis-positionings by all possible users in different genders and ages, the sizes of the sensors are successfully optimized for satisfactory average signal quality over all possible users.
Encapsulating peritoneal sclerosis in liver transplant recipients: a report of 2 cases (2017)

Encapsulating peritoneal sclerosis (EPS) is a rare cause of intestinal obstruction by a thick fibrous membrane wrapping around the small intestine. It is a possible complication after liver transplantation (LT) that can be fatal. This report describes 2 cases of EPS after LT that were successfully treated with surgery, corticosteroids, tamoxifen, and mammalian target of rapamycin inhibitor. After treatment in both cases, the patients were able to start oral feeding and have been symptom free for more than 1 year. These cases suggests that for the management of EPS, surgical treatment is mandatory when the patients present with symptoms of intestinal obstruction or if there are findings suggestive of decreased mural perfusion. Surgery should be accompanied with medical treatment to prevent the relapse of EPS.
Dual-Band Aerial Networks for Priority-Based Traffic (2023)

Unmanned aerial vehicle networks suffer from lackluster performance due to line-of-sight issues as well as resource scarcity. Network slicing, multi-band transmission, and numerology show great potential in mitigating such limitations. In this work, we propose the use of the sub-6 GHz and mmWave bands, the latter of which requires careful consideration of line-of-sight, with numerology for aerial network slicing to provision time-critical services and broadband access. Accordingly, we formulate a user admission control policy to regulate band access after which we formulate a joint resource block and power allocation problem, a mixed-integer non-linear programming problem, to minimize the quality-of-service gap of the throughput-dependent broadband users as a best-effort service and meet the time-critical service requirements. We propose a low-complexity algorithm, PREDICT, to tackle the formulated problem and present extensive simulation results to validate the advantages of our scheme.
The effects of self-perception during video conversation using Zoom on self-focused attention and post-event processing of social anxiety : A randomized controlled study (2022)

본 연구는 화상대화를 하는 동안 자기지각 여부에 따른 자기초점주의와 사후처리의 변화양상을 확인하고 자 했다. 80명의 성인을 대상으로 고 사회불안집단과 저 사회불안집단을 선별하였다. 화상대화 시 자기 얼 굴제시 여부로 무선 배정하여 최종 4집단을 구성하였다. 참가자들은 5분 동안 낯선 이성과 화상대화에 참 여하였으며 화상대화 전, 직후, 24시간 후 각각 설문에 응하였다. 화상대화 전과 직후 얼굴지각, 자기초점 주의, 사후처리 수준의 차이를 확인한 결과, 얼굴지각에 따른 자기초점주의 수준의 차이는 유의하지 않았 다. 고 사회불안집단에서는 저 사회불안집단보다 화상대화 직후 및 24시간 후 사후처리 수준이 모두 높게 나타났다. 이에 대한 상관분석 결과, 고 사회불안집단에서 얼굴 확인 정도가 부정적 평가 예상 정도 및 사 후처리와 정적상관을 보였으며, 저 사회불안집단에서는 얼굴 확인 정도가 긍정적 평가 예상 정도, 상태 자 기초점주의 및 상태 외부초점주의와 정적상관이 나타났다. 사회불안이 높은 집단에서 얼굴지각과 사후처리 사이의 기제를 확인하기 위해 매개분석을 실시하였다. 그 결과, 고 사회불안집단의 경우에만 자신의 얼굴 을 지각하면 부정적 평가에 대한 예상을 하게 되며 이는 화상대화 24시간 후의 사후처리에 영향을 미치는 것으로 나타났다. 본 연구는 COVID-19로 인해 화상회의 및 수업이 증가한 상황에서 사람들이 자신의 얼굴 을 보는 것에 불편감을 느끼는 이유에 대한 함의를 제공하며, 사회불안장애 특정적인 사후처리가 대면뿐만 아니라 온라인 사회적 상호작용 후에도 나타남을 확인하였다.
ChemInform Abstract: Unexpected Remarkable Stability of Primary Ozonides Derived from Alkenyl Stannanes. One‐Pot Synthesis of 1,2‐Diols from Alkynes. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A Closed-Form Analytical Estimation of Vertical Displacement Error in Pedestrian Navigation (2020)

We present an analytical expression for estimating the position error in the vertical direction in pedestrian navigation using an Inertial Measurement Unit (IMU) aided by an altimeter. The analytical expression is found to be directly proportional to the altimeter resolution, the square root of the altimeter sampling rate, IMU Velocity Random Walk (VRW), and a ratio of time intervals in the stance phase and the swing phase during the gait cycle, and inversely proportional to the square root of IMU sampling rate. The analytical analysis was verified by numerical simulations and supported by experimental results. The numerical simulation of the ZUPT-augmented navigation aided by an altimeter was conducted based on a mathematically simulated foot motion trajectory. Experiments were implemented on a foot-mounted platform containing IMUs and altimeters. The results from both simulations and experiments matched our analytical prediction, with an error less than 20%.
Effects of diaphenylsulphone (dapsone) against plasmodium vivax of South West Pacific origin (1968)

Studies were carried out to assess the blood schizontocidal effects of dapsone in children with naturally acquired P. vivax infections and to assess its blood schizontocidal and possible tissue schizontocidal effects in adult volunteers infected with the Chesson strain of P. vivax. The effects against P. vivax of South West Pacific origin were unimpressive.
Diacetylene-terminated diacetylene-containing polysiloxanes (2002)

The presence of terminal diacetylenes in a diacetylene-containing poly(dimethylsiloxane) is demonstrated to emphasize their use as an alternative to other thermally reactive end groups for polymer cross-linking.