gebhart/patrepeval huggingface dataset:
Optimal treatment and rational reuse of water in textile industry (1999)

Because of the increasing water shortage in Flandres (Belgium), it will be necessary to switch over to alternative industrial water supply sources. The reuse of a part of the effluent requires the development and application of advanced water purification treatments in combination with process control. The current technologies under development in the frame of an EU-project are outlined. The latter project covers an integrated process for the provision of recycled water of guaranteed quality with minimum emissions. The whole process is divided into three modules; a sensor protected aerobic stage (SPAS), an anaerobic treatment (ANASORB) and a holistic polishing (HOLIPOL) module. The modules are flexible in application and can be used separately or together. The case of a jeans finishing plant in which a total recycling system at full scale is operated, is discussed.
Datalink streaming in wireless sensor networks (2006)

Datalink layer framing in wireless sensor networks usually faces a trade-off between large frame sizes for high channel bandwidth utilization and small frame sizes for effective error recovery. Given the high error rates of intermote communications, TinyOS opts in favor of small frame sizes at the cost of extremely low channel bandwidth utilization. In this paper, we describe Seda: a streaming datalink layer that resolves the above dilemma by decoupling framing from error recovery. Seda treats the packets from the upper layer as a continuous stream of bytes. It breaks the data stream into blocks, and retransmits erroneous blocks only (as opposed to the entire erroneous frame). Consequently, the frame-error-rate (FER), the main factor that bounds the frame size in the current design, becomes irrelevant to error recovery. A frame can therefore be sufficiently large in great favor of high utilization of the wireless channel bandwidth, without compromising the effectiveness of error recovery. Meanwhile, the size of each block is configured according to the error characteristics of the wireless channel to optimize the performance of error recovery. Seda has been implemented as a new datalink layer in the TinyOS, and evaluated through both simulations and experiments in a testbed of 48 MicaZ motes. Our results show that, by increasing the TinyOS frame size from the default 29 bytes to 100 bytes (limited by the buffer space at MicaZ firmware), Seda improves the throughput around 25% under typical wireless channel conditions. Seda also reduces the retransmission traffic volume by more than 50%, compared to a framebased retransmission scheme. Our analysis also exposes that future sensor motes should be equipped with radios with more packet buffer space on the radio firmware to achieve optimal utilization of the channel capacity.
The effect of dye molecules in titania‐silica hybrid coatings for corrosion protection (2010)

Purpose The purpose of this paper is to develop a corrosion resistant zinc‐free coating for interstitial free steel. Design/methodology/approach The objective was achieved by developing a titania‐silica hybrid coating through a sol‐gel process by incorporating a dye molecule. The role of dye molecules was particularly important for enhancing the anti‐corrosion properties of the coating. The approach of current research was to develop a low‐temperature coating process that can bring similar performance to that obtained in case of zinc coating. Titania and silica precursors were mixed by stirring under a nitrogen atmosphere at 80°C to formulate a low‐temperature coating. The dye molecules were added before addition of water for subsequent hydrolysis. This complete formulation was applied over steel sheets using a roll coater as the application method. Findings The ranking order of improved corrosion resistance was found to be PATMS&gt;EETMS&gt;GPTMS and the addition of trace amount of tartrazine dye (60‐65 mg/l of liquid) in PATMS increased the corrosion service life in saline environments from 168 to 216 h, thus showing a promising improvement. Scanning Kelvin Probe results indicated that the corrosion reaction is controlled cathodically in presence of dye and, electrochemical impedance spectroscopy results exhibited a charge transfer resistance (Ct) of coating with dye of 419Ω cm 2 , which was higher than that of a similar coating without dye (360Ω cm 2 ), indicating increased corrosion protection. Research limitations/implications This coating had improved barrier protection but lacked cut edge protection. Future work will focus on adding sacrificial protection by introducing compatible corrosion inhibitors, especially dye molecules, which are photosensitive. Practical implications This coating has huge potential for use in the automotive sector, especially for certain automotive parts (i.e. helm flanges), which suffer from poor durability in salty and high‐humidity atmospheres. Social implications Since this coating formulation utilises a partially aqueous base, some environmental impact cannot be avoided, but it will have less impact than a complete solvent base formulation. Originality/value The novelty of the work was the introduction of dye molecules as the corrosion inhibitor and their compatibility in the hybrid coating system.
1991 Volvo Award in Experimental Studies (1991)

An animal model of cauda equina syndrome was developed. Neurologic recovery was analyzed following immediate, early, and delayed decompression. Five experimental groups, each containing six dogs, were studied. Compression of the cauda equina was performed in all 30 dogs following an L6-7 laminectomy. The cauda equina was constricted by 75% in each group. The first group was constricted and immediately decompressed. The remaining groups were constricted for 1 hour, 6 hours, 24 hours, and 1 week, respectively, before being decompressed. Somatosensory evoked potentials were performed before and after surgery, before and immediately after decompression, and 6 weeks following decompression. Daily neurologic exams using the Tarlov grading scale were performed. At 6 weeks postdecompression, all dogs were killed, and the neural elements analyzed histologically. Following compression, all 30 dogs had significant lower extremity weakness, tail paralysis, and urinary incontinence. All dogs recovered significant motor function 6 weeks following decompression. The dogs with immediate decompression generally recovered neurologic function within 2-5 days. The dogs receiving 1-hour and 6-hour compression recovered within 5-7 days. The dogs receiving 24-hour compression remained paraparetic 5-7 days, with bladder dysfunction for 7-10 days and tail dysfunction persisting for 4 weeks. The dogs with compression for 1 week were paraparetic (Tarlov Grade 2 or 3) and incontinent during the duration of cauda equina compression. They recovered to walking by 1 week and Tarlov Grade 5 with bladder and tail control at the time of euthanasia. Immediately after compression, all five groups demonstrated at least 50% deterioration of the posterior tibial nerve evoked potential amplitudes. Six weeks after decompression, all five groups had a mean amplitude recovery of 20-30%. There were no statistical differences in recovery of somatosensory evoked potentials among the groups. Histologic analysis of the cauda equina in all groups demonstrated scattered wallerian degeneration and axonal regeneration. Areas of poor myelination, fibrosis, and macrophage activity were seen at the level of constriction. There were no significant differences in the histologic neuroanatomy of the five groups. It has been advocated that early decompression of cauda equina syndrome enhances neurologic recovery. This study does not support this premise. Although decompression allowed significant recovery in all 30 dogs, no significant differences were found in somatosensory evoked potentials, neurologic recovery, or histopathology in groups decompressed immediately, at 1 hour, 6 hours, 24 hours, or 1 week.
Characterisation of ultrasonic structural noise in multiple scattering media using phased arrays (2013)

Conference of 11th Anglo-French Physical Acoustics Conference, AFPAC 2012 ; Conference Date: 18 January 2012 Through 20 January 2012; Conference Code:98821
Exploring Processor Design Options for Java-Based Middleware (2005)

Java-based middleware is a rapidly growing workload for high-end server processors, particularly chip multiprocessors (CMP). To help architects design future microprocessors to run this important new workload, we provide a detailed characterization of two popular Java server benchmarks, ECperf and SPECjbb2000. We first estimate the amount of instruction-level parallelism in these workloads by simulating a very wide issue processor with perfect caches and perfect branch predictors. We then identify performance bottlenecks for these workloads on a more realistic processor by selectively idealizing individual processor structures. Finally, we combine our findings on available ILP in Java middleware with results from previous papers that characterize the availibility of TLP to investigate the optimal balance between ILP and TLP in CMPs. We find that, like other commercial workloads, Java middleware has only a small amount of instruction-level parallelism, even when run on very aggressive processors. When run on processors resembling currently available processors, the performance of Java middleware is limited by frequent traps, address translation and stalls in the memory system. We find that SPECjbb2000 differs from ECperf in two meaningful ways: (1) the performance of ECperf is affected much more by cache and TLB misses during instruction fetch and (2) SPECjbb2000 has more memory-level parallelism.
Genomic Characterization of ERBB2-Driven Biliary Cancer and a Case of Response to Ado-Trastuzumab Emtansine (2019)

<i>ERBB2</i> alterations are present in 5.4% of BTCs. When present, the degree of <i>ERBB2</i> gene amplification is often high, and S310 codon mutations are the most common hotspot. These features, along with the presented case, support further development of human epidermal growth factor receptor 2-targeted therapy in <i>ERBB2</i>-mutant and/or -amplified BTC.
Germanium Based Field-Effect Transistors: Challenges and Opportunities (2014)

The performance of strained silicon (Si) as the channel material for today's metal-oxide-semiconductor field-effect transistors may be reaching a plateau. New channel materials with high carrier mobility are being investigated as alternatives and have the potential to unlock an era of ultra-low-power and high-speed microelectronic devices. Chief among these new materials is germanium (Ge). This work reviews the two major remaining challenges that Ge based devices must overcome if they are to replace Si as the channel material, namely, heterogeneous integration of Ge on Si substrates, and developing a suitable gate stack. Next, Ge is compared to compound III-V materials in terms of <i>p</i>-channel device performance to review how it became the first choice for PMOS devices. Different Ge device architectures, including surface channel and quantum well configurations, are reviewed. Finally, state-of-the-art Ge device results and future prospects are also discussed.
Hodgkin Lymphoma in Adults (2018)

The highly favorable long-term prognosis of HL necessitates careful consideration of the intensity of treatment as well as thorough follow-up to enable the detection of late sequelae, such as second tumors or organ damage.
ChemInform Abstract: Amino Acids and Peptides. Part 52. Design and Synthesis of Opioid Mimetics Containing a Pyrazinone Ring and Examination of Their Opioid Receptor Binding Activity. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Pedestrian recognition in automotive radar sensors (2013)

Automotive radar sensors in the 24 GHz frequency domain measure target range and Doppler frequency simultaneously even in multiple target situations. The all weather capability of radar sensors is an important argument for their application in modern cars and in driver assistant systems. The measurement accuracy and target resolution depends on the applied waveform. Therefore the Multi Frequency Shift Keying (MFSK) and the Chirp Sequence waveform will be considered and compared in this paper. The classical radar sensor measures target range, radial velocity and azimuth angle. Additionally the radar sensor should be able to distinguish between different objects like pedestrians and cars in automotive applications. In this case the target recognition quality depends mainly on the signal-to-noise ratio (SNR), the signal features and their measurement accuracy, respectively. In this paper the quality of the target recognition process will be quantitatively measured and compared for two different radar waveforms. © 2013 German Inst of Navigation.
μHall Chip for Sensitive Detection of Bacteria (2013)

Sensitive, rapid and phenotype-specific enumeration of pathogens is essential for the diagnosis of infectious disease, monitoring of food chains, and for defense against bioterrorism. Microbiological culture and genotyping, techniques that sensitively and selectively detect bacteria in laboratory settings, have limited application in clinical environments due to high cost, slow response times, and the need for specially trained staff and laboratory infrastructure. To address these challenges, we developed a microfluidic chip-based micro-Hall (μHall) platform capable of measuring single, magnetically tagged bacteria directly in clinical specimens with minimal sample processing. We demonstrated the clinical utility of the μHall chip by enumerating Gram-positive bacteria. The overall detection limit of the system was similar to that of culture tests (~10 bacteria), but the assay time was 50-times faster. This low-cost, single-cell analytical technique is especially well-suited to diagnose infectious diseases in resource-limited clinical settings.
MCAM contributes to the establishment of cell autonomous polarity in myogenic and chondrogenic differentiation (2017)

ABSTRACT Cell polarity has a fundamental role in shaping the morphology of cells and growing tissues. Polarity is commonly thought to be established in response to extracellular signals. Here we used a minimal in vitro assay that enabled us to monitor the determination of cell polarity in myogenic and chondrogenic differentiation in the absence of external signalling gradients. We demonstrate that the initiation of cell polarity is regulated by melanoma cell adhesion molecule (MCAM). We found highly polarized localization of MCAM, Moesin (MSN), Scribble (SCRIB) and Van-Gogh-like 2 (VANGL2) at the distal end of elongating myotubes. Knockout of MCAM or elimination of its endocytosis motif does not impair the initiation of myogenesis or myoblast fusion, but prevents myotube elongation. MSN, SCRIB and VANGL2 remain uniformly distributed in MCAM knockout cells. We show that MCAM is also required at early stages of chondrogenic differentiation. In both myogenic and chondrogenic differentiation MCAM knockout leads to transcriptional downregulation of Scrib and enhanced MAP kinase activity. Our data demonstrates the importance of cell autonomous polarity in differentiation.
Wound Healing Activity of Opuntia ficus-indica Fixed Oil Formulated in a Self-Nanoemulsifying Formulation (2021)

OFI possesses wound healing properties that are enhanced by self-emulsification of the oil into nano-droplets. The observed activity can be attributed, at least partly, to its anti-inflammatory, pro-collagen and angiogenic properties.
Removal of Methylene Blue Dye from Aqueous Solution by Using Powdered Saccharum Arundinaceum Leaves (2017)

Dye removal from industrial effluents is an important environmental concern. Various physical and chemical treatment methods can serve this purpose, of which the most economical and effective one is adsorption. Extraction of dyes from industrial water by adsorption using low cost alternative adsorbent is a demanding area as it has double benefits i.e., water treatment and waste management. Natural material used an extractant for dyes has the advantage of offering an effected low cost replacement and environmental friendly as compared to other techniques for extraction of dyes. In the present study, for the first time we have successfully extract65-95 % of Methylene blue dye from industrial waste water by means of finely grained sample of Saccharum arundinaceum leaves as an extractant. A batch adsorption experiment was used for the biosorption process, the effect of concentration, temperature, contact time, pH and rpm was studied for the extraction of Methylene blue dye from industrial wastewater.The optimum contact time was two hour for Methylene blue dye.The data are well represented by Langmuir isotherms indicating favorable adsorption of methylene blue by the adsorbent. Langmuir type I is the best fit isotherm for representing the experimental data. Kinetic analysis shows that, Saccharum arundinaceum is best bio sorbent for the elimination of Methylene blue dye from industrial waste water.
Incorporating silica‐coated graphene in bioceramic nanocomposites to simultaneously enhance mechanical and biological performance (2020)

The applications of a variety of bioactive ceramics such as hydroxyapatite (HA) in orthopedics are limited by their insufficient mechanical properties, especially poor fracture toughness. Thus, further extending the clinical applications of these materials warrants the enhancement of their mechanical properties. Although the reinforcement of ceramics by 2D nanomaterials has been well recognized, integrated structural, mechanical, and functional considerations have been neglected in the design and synthesis of such composite materials. Herein, we report the first use of silica-coated reduced graphene oxide (S-rGO) hybrid nanosheets to create bioceramic-based composites with simultaneously enhanced mechanical and biological properties. In the representative HA-based bioceramic systems prepared by spark plasma sintering, S-rGO incorporation was found to be more effective for increasing the Young's modulus, hardness, and fracture toughness than the incorporation of uncoated reduced GO (rGO). Furthermore, when assessed with osteoblast-like MG-63 cells, such novel materials led to faster cell proliferation and higher cell viability and alkaline phosphatase activity than are generally observed with pure HA; additionally, cells demonstrate stronger affinity to S-rGO/HA than to rGO/HA composites. The S-rGO/bioceramic composites are therefore promising for applications in orthopedic tissue engineering, and this research provides valuable insights into the fabrication of silica-coated hybrid nanosheet-reinforced ceramics.
Abstract 5606: GlycoConnect™ immune cell engagers (GC™-ICEs). A non-genetic approach to targeted IL-15 immunotherapy (2022)

Abstract Engagement of T cell or NK cells to harness a patient’s immune system is a promising approach in immuno-oncology. An immunocytokine, i.e. a tumor-targeting antibody (fragment) genetically fused to an immunostimulatory cytokine, is specifically designed for this purpose. Fusion antibody-IL-15 immunocytokines, based on a variety of molecular architectures, are currently finding their way to the clinic with promising results. Here we demonstrate how GlycoConnect™, a site-specific conjugation technology anchoring on the native antibody glycan, can be applied for attachment of IL-15 without prior antibody engineering. The molecular architecture of the resulting immune cell engagers (ICEs) can be readily tailored to 2:2 or 2:1 ratio (anti-TAA:IL-15) to mitigate cytokine release syndrome. Moreover, we show how immunostimulatory activity can be regulated via linker design, either by tailoring of IL-15-antibody spacing or by generation of a conditionally active IL-15 format. Structural and functional studies will be presented to corroborate the architecture of these GC™-ICEs and in vitro and in vivo activity in a syngeneic mouse model. Citation Format: Remon van Geel, Floris van Delft. GlycoConnect™ immune cell engagers (GC™-ICEs). A non-genetic approach to targeted IL-15 immunotherapy [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2022; 2022 Apr 8-13. Philadelphia (PA): AACR; Cancer Res 2022;82(12_Suppl):Abstract nr 5606.
The Effect of Anterior Cruciate Ligament Femoral Entheseal Shape on Ligament Strain (2015)

Undergraduate Research Opportunity Program (UROP)
Supplementary Figures 1-8 from Loss of <i>Phosphatase and Tensin Homologue Deleted on Chromosome 10</i> Engages ErbB3 and Insulin-Like Growth Factor-I Receptor Signaling to Promote Antiestrogen Resistance in Breast Cancer (2023)

Supplementary Figures 1-8 from Loss of &lt;i&gt;Phosphatase and Tensin Homologue Deleted on Chromosome 10&lt;/i&gt; Engages ErbB3 and Insulin-Like Growth Factor-I Receptor Signaling to Promote Antiestrogen Resistance in Breast Cancer
The Pd-catalyzed fluorination of (hetero)aryl bromides and triflates (2015)

Thesis: Ph. D. in Organic Chemistry, Massachusetts Institute of Technology, Department of Chemistry, 2015.
EXCITED STATE DYNAMICS OF $Cu^{+}$ IN NaF MOST CRYSTAL (1983)

The one and two-photon spectra of $NaF:Cu^{+}$ showed a zero photon line and a progression of the $t_{1u}$ mode $(Cu^{+}$ moving off-center) in the $^{1}A_{1g}\\rightarrow^{1}E_{g}, ^{1}T_{2g}$ transitions at $2^{\\circ} K$ . the spectra have been fitted with a 3-dimensional mixed quartic-harmonic potential including a crystal field term. The increasing widths of successive members of the progression are related to the increasing density of states of the NaF lattice. Coupling of the $t_{1u}$ mode to the Jahn-Teller potential in the $^{1}E_{g}$ state has clearly observable effects. Other aspects of this unusual example will be discussed.
MIIT: International in-situ testing of simulated HLW forms - performance of SRS simulated waste glass after 6 mos. , 1 yr. , 2 yrs. and 5 yrs. of burial at WIPP (1991)

The first field test, involving burial of simulated high-level waste (HLW) forms and package components, to be conducted in the United States, was begun in July of 1986. This program, called the Materials Interface Interactions Test or MIIT, comprises the largest cooperative field-testing venture in the international waste management community. Included in the study are over 900 waste form samples comprising 15 different systems supplied by 7 countries. Also included are about 300 potential canister or overpack metal samples along with more than 500 geologic and backfill specimens. There are almost 2000 relevant interactions that characterize this effort which is being conducted in the bedded salt site at the Waste Isolation Pilot Plant (WIPP), near Carlsbad, New Mexico. The MIIT program represents a joint effort managed by Sandia National Laboratories in Albuquerque, N.M., and Savannah River Laboratory in Aiken, S.C. and sponsored by the US Department of Energy. Also involved in MIIT are participants from various laboratories and universities in France, Germany, Belgium, Canada, Japan, Sweden, the United Kingdom, and the United States. In July of 1991, the experimental portion of the 5-yr. MIIT program was completed. Although only about 5% of all MIIT samples have been assessed thus far, there are already interesting findings that have emerged. The present paper will discuss results obtained for SRS 165/TDS waste glass after burial of 6 mo., 1 yr. and 2 yrs., along with initial analyses of 5 yr. samples.