gebhart/patrepeval huggingface dataset:
Reservoir Fluid Characterization and Application for Simulation Study (2011)

Abstract The paper presents a methodology to develop and apply an equation-of-state (EOS) multi-fluid model for a field in Tunisia. The EOS model was developed by matching measured PVT data for a near-critical oil sample. The fluid characterization was used to estimate contamination level in oil-based-mud contaminated MDT samples, calculate decontaminated sample composition, estimate zone composition based on clean-up test measured oil-gas ratio, estimate fluid composition of some layers where samples were not available, and study the effect of gas condensate blockage and capillary number on simulated well performance. In this field, reservoir fluids range from lean gas condensate to rich gas condensate and volatile oil. Clean up tests were conducted for all four zones encountered in the well, and oil-gas ratios were measured. During the clean up test of one zone, a near critical oil sample was collected and standard PVT experiments were conducted. Oil based mud (OBM) contaminated MDT samples were collected from six of the nine non-communicating layers, with OBM contamination levels between 20–65 wt% STO. An EOS model was developed after matching measured PVT data on the near-critical oil sample. The MDT samples were decontaminated using measured mud composition. The calculated decontaminated "clean" sample compositions were used in a reservoir simulation model to initialize the layer from which the MDT sample was taken. The developed EOS model was also used to estimate the fluid composition of different zones and layers without fluid samples. The zone fluid compositions were calculated based on measured test OGR. The EOS model, zone fluid compositions, decontaminated MDT samples, and layer mobilities were used to estimate fluid composition of the layers without samples. This paper provides a methodology that can be used in any other field.
MSR Identity Toolbox v1.0: A MATLAB Toolbox for Speaker Recognition Research (2013)

We are happy to announce the release of the MSR Identity Toolbox: A MATLAB toolbox for speaker-recognition research. This toolbox contains a collection of MATLAB tools and routines that can be used for research and development in speaker recognition. It provides researchers with a test bed for developing new front-end and back-end techniques, allowing replicable evaluation of new advancements. It will also help newcomers in the field by lowering the barrier to entry, enabling them to quickly build baseline systems for their experiments. Although the focus of this toolbox is on speaker recognition, it can also be used for other speech related applications such as language, dialect, and accent identification. Additionally, it provides many of the functionalities available in other open-source speaker recognition toolkits (e.g., ALIZE
Successful Use of Infliximab in the Treatment of Corticosteroid Dependent Collagenous Colitis (2013)

Pola, Suresh MD; Fahmy, Marianne MD; Evans, Elisabeth NP; Tipps, Ann MD; Sandborn, William J MD Author Information
Estimating the Relative Water Content of Leaves in a Cotton Canopy (2017)

Remotely sensing plant canopy water status remains a long-term goal of remote sensing research. Established approaches to estimating canopy water status the Crop Water Stress Index, the Water Deficit Index and the Equivalent Water Thickness involve measurements in the thermal or reflective infrared. Here we report plant water status estimates based upon analysis of polarized visible imagery of a cotton canopy measured by ground Multi-Spectral Polarization Imager (MSPI). Such estimators potentially provide access to the plant hydrological photochemistry that manifests scattering and absorption effects in the visible spectral region.Twice during one day, +- 3 hours from solar noon, we collected polarized imagery and relative water content data on a cotton test plot located at the Arid Land Agricultural Research Center, United States Department of Agriculture, Maricopa, AZ. The test plot, a small portion of a large cotton field, contained stressed plants ready for irrigation. The evening prior to data collection we irrigated several rows of plants within the test plot. Thus, ground MSPI imagery from both morning and afternoon included cotton plants with a range of water statuses. Data analysis includes classifying the polarized imagery into sunlit reflecting, sunlit transmitting, shaded foliage and bare soil. We estimate the leaf surface reflection and interior reflection based upon the per pixel polarization and sunview directions. We compare our cotton results with our prior polarization results for corn and soybean leaves measured in the lab and corn leaves measured in the field.
Stability of Zr-Doped SrCeO3-d Under Wet CO/CO2 Atmospheres (2008)

The SrCeO3-based perovskite is a potential hydrogen membrane material used to incorporate the water gas shift reaction catalyst and hydrogen separation into one unit. The stability of SrCeO3 was improved using zirconium dopant. A tubular hydrogen membrane was fabricated with NiO-SrCe0.8Zr0.2O3 and SrCe0.7Zr0.2Eu0.1O3 as the substrate and membrane, respectively. The hydrogen permeation flux was stable under wet CO atmosphere.
Book reviews (1981)

ORIGINS OF THE STUDY OF HUMAN GROWTH: By Edith Boyd. University of Oregon Health Sciences Center, Portland, 1980.610pp. $65, cloth. THE WHISPERINGS WITHIN: EVOLUTION AND THE ORIGIN OF HUMAN NATURE: By David P. Barash. Penguin Books, New York, 1979. 274 pp. (A reprint of the 1979 edition published by Harper & Row, New York). DISEASE AND URBANIZATION: Edited by E. J. Clegg and J. P. Garlick. Taylor & Francis Ltd., London, 1980. 171 pp. $22.25, cloth.
ChemInform Abstract: Photo‐Emde Degradation of 1,2,3,4‐Tetrahydroquinolinium Salts. (1986)

Abstract In order to corroborate the proposed mechanism of (I)‐ (IVa) via the intermediate (IIIa), the photochemical (direct irradiation through quartz) cleavage of the N ‐ Cbond in quinolinium salts (III) is examined (named "photo‐emde degradation" in analogy to the Emde degradation reaction using Na ‐ Hg).
Corrigendum: Carbon Molecular Sieve Membrane Preparation by Economical Coating and Pyrolysis of Porous Polymer Hollow Fibers (2020)

The authors of this Communication became aware of an error in Table In this Table, the sheath dope polymer and NMP masses were reversed. The correct Table This error affects no other feature of the Supporting Information or manuscript since the correct compositions were used in the study.Nochanges in analysis or conclusions result from this correction.
A New Method for the Deprotection of Benzyl Esters (1994)

N-Bromosuccinimide can be used to selectively convert benzyl esters into carboxylic acids under neutral conditions. This method provides an alternative complementary method to hydrogenolysis.
Data from Identification and Characterization of NVP-BKM120, an Orally Available Pan-Class I PI3-Kinase Inhibitor (2023)

&lt;div&gt;Abstract&lt;p&gt;Following the discovery of NVP-BEZ235, our first dual pan-PI3K/mTOR clinical compound, we sought to identify additional phosphoinositide 3-kinase (PI3K) inhibitors from different chemical classes with a different selectivity profile. The key to achieve these objectives was to couple a structure-based design approach with intensive pharmacologic evaluation of selected compounds during the medicinal chemistry optimization process. Here, we report on the biologic characterization of the 2-morpholino pyrimidine derivative pan-PI3K inhibitor NVP-BKM120. This compound inhibits all four class I PI3K isoforms in biochemical assays with at least 50-fold selectivity against other protein kinases. The compound is also active against the most common somatic PI3Kα mutations but does not significantly inhibit the related class III (Vps34) and class IV (mTOR, DNA-PK) PI3K kinases. Consistent with its mechanism of action, NVP-BKM120 decreases the cellular levels of p-Akt in mechanistic models and relevant tumor cell lines, as well as downstream effectors in a concentration-dependent and pathway-specific manner. Tested in a panel of 353 cell lines, NVP-BKM120 exhibited preferential inhibition of tumor cells bearing PIK3CA mutations, in contrast to either KRAS or PTEN mutant models. NVP-BKM120 shows dose-dependent &lt;i&gt;in vivo&lt;/i&gt; pharmacodynamic activity as measured by significant inhibition of p-Akt and tumor growth inhibition in mechanistic xenograft models. NVP-BKM120 behaves synergistically when combined with either targeted agents such as MEK or HER2 inhibitors or with cytotoxic agents such as docetaxel or temozolomide. The pharmacological, biologic, and preclinical safety profile of NVP-BKM120 supports its clinical development and the compound is undergoing phase II clinical trials in patients with cancer. &lt;i&gt;Mol Cancer Ther; 11(2); 317–28. ©2011 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
IEEE 802.16m Radio Access Technology (2013)

The requirements for the Institute of Electrical and Electronics Engineers (IEEE) 802.16m standard were selected to ensure competitiveness with the emerging fourth-generation radio access technologies, while extending and significantly improving the functionality and efficiency of the legacy system. This chapter describes the prominent functional features of IEEE 802.16m radio access technology including air-interface protocols, and physical layer and medium access control functional components. The International Mobile Telephone-Advanced requirements defined and approved by International Telecommunications Union-Radio (ITU-R) and published as Report ITU-R M.2134, referred to as target requirements in the IEEE 802.16m system requirement document, were evaluated based on the methodology and guidelines specified by Report ITU-R M.2135-1. The mobile station state diagram for the IEEE 802.16m is similar to that of the legacy system with the exception of the initialization state that has been simplified to reduce the scan latency and to enable fast cell selection or reselection.
Diversity of influenza A virus subtypes isolated from domestic poultry in Hong Kong. (1979)

The second phase of a 2-year influenza virus surveillance programme of domestic avian species in Hong Kong (up to October 1977) yielded influenza A virus, Newcastle disease virus, and Hong Kong paramyxovirus, as well as unidentified haemagglutinating agents. These viruses were isolated from the trachea or cloaca of apparently healthy domestic ducks, geese, and chickens originating from China and Hong Kong. Twenty-five combinations of haemagglutinin and neuraminidase surface antigens were identified from the 136 influenza A viruses isolated. Eight of the combinations do not appear to have been previously reported - Hav3Nav2, Hav4Nav2, Hav4Nav4, Hav4Nav5, Hav4Neq1, Hav6Nav4, Hav6Nav6, and Hav9Nav1. The existence of such a diverse pool of influenza virus genetic information may play a role in the emergence of new human pandemic strains.
Pseudomonas aeruginosa cystic fibrosis clinical isolates produce exotoxin A with altered ADP-ribosyltransferase activity and cytotoxicity The GenBank accession numbers for the toxA sequences are: strain 4384, AF227419; strain 5154, AF227420; strain 5166, AF227421; strain 5552, AF227422; strain 5585, AF227423; strain 5588, AF227424. (2000)

The role of Pseudomonas aeruginosa exotoxin A (ETA) as a virulence factor in the lung infections of cystic fibrosis (CF) patients is not well understood. Transcript-accumulation studies of bacterial populations in sputum reveal high levels of transcription of toxA, which encodes ETA, in some patients with CF. However, in general, tissue damage in the lungs of patients with CF does not seem to be consistent with a high level of expression of active ETA. To address this discrepancy the authors analysed the production and activity of ETA produced by a number of P. aeruginosa CF isolates. One CF isolate, strain 4384, transcribed toxA at levels similar to the hypertoxigenic strain PA103 but produced an ETA with reduced ADP-ribosyltransferase (ADPRT) activity. Complementation in trans of strain 4384 with the wild-type toxA and a mixed toxin experiment suggested the absence of inhibitory accessory factors within this strain. The toxA gene from strain 4384 was cloned and sequenced, revealing only three mutations in the gene, all within the enzymic domain. The first mutation changed Ser-410 to Asn. The second mutation was located within an alpha-helix, altering Ala-476 to Glu. The third mutation, Ser-515 to Gly, was found at the protein surface. To date, Ser-410, Ala-476 and Ser-515 have not been reported to play a role in the ADPRT activity of ETA. However, it may be the combination of these mutations that reduces the enzymic activity of ETA produced by strain 4384. Expression of 4384 toxA and wild-type toxA in an isogenic strain revealed that 4384 ETA had 10-fold less ADPRT activity than wild-type ETA. ETA purified from strain 4384 also demonstrated 10-fold less ADPRT activity as compared to wild-type ETA. Cytotoxicity assays of purified ETA from strain 4384 indicated that the cytotoxicity of 4384 ETA is not reduced; it may be slightly more toxic than wild-type ETA. Analysis of five other CF isolates revealed a similar reduction in ADPRT activity to that seen in strain 4384. Sequence analysis of the enzymic domain of toxA from the five CF strains identified a number of mutations that could account for the reduction in ADPRT activity. These results suggest that some CF isolates produce an ETA with reduced enzymic activity and this may partially explain the pathogenesis of chronic lung infections of CF due to P. aeruginosa.
RF beam transmission of x-band PAA system utilizing large-area, polymer-based true-time-delay module developed using imprinting and inkjet printing (2016)

Phased-array antenna (PAA) technology plays a significant role in modern day radar and communication networks. Truetime- delay (TTD) enabled beam steering networks provide several advantages over their electronic counterparts, including squint-free beam steering, low RF loss, immunity to electromagnetic interference (EMI), and large bandwidth control of PAAs. Chip-scale and integrated TTD modules promise a miniaturized, light-weight system; however, the modules are still rigid and they require complex packaging solutions. Moreover, the total achievable time delay is still restricted by the wafer size. In this work, we propose a light-weight and large-area, true-time-delay beamforming network that can be fabricated on light-weight and flexible/rigid surfaces utilizing low-cost "printing" techniques. In order to prove the feasibility of the approach, a 2-bit thermo-optic polymer TTD network is developed using a combination of imprinting and ink-jet printing. RF beam steering of a 1×4 X-band PAA up to 60° is demonstrated. The development of such active components on large area, light-weight, and low-cost substrates promises significant improvement in size, weight, and power (SWaP) requirements over the state-of-the-art.
Field evaluation of oxygen-enriched air staging at anchor glass. Topical report, December 1991-July 1994 (1995)

The glass industry in the United States is reportedly the fourth largest industrial energy consumer. The majority of the glass -- representing container, flat, pressed, and blown -- is produced in relatively large (100 to 1000 ton/d) regenerative glass tanks, which operate continuously for up to 10 years. Although there are currently no national regulations on NOx emissions in the United States, this could change in light of the 1990 Clean Air Act. There is a need to develop advanced cost-effective low-NOx technologies for retrofit to natural gas-fired regenerative glass melters. The objective of this phase of the program was to field evaluate an oxygen-enriched air staging technique on an endport glass tank for a 35% or higher NOx reduction. Data collected during this operation show 35% to 50% NOx reduction to below 2.5 lb/ton of glass produced.
Privacy-Preserving Verification of Clinical Research (2014)

Abstract: We treat the problem of privacy-preserving statistics verification in clinical research. We show that given aggregated results from statistical calculations, we can verify their correctness efficiently, without revealing any of the private inputs used for the calculation. Our construction is based on the primitive of Secure Multi-Party Com-putation from Shamir’s Secret Sharing. Basically, our setting involves three parties: a hospital, which owns the private inputs, a clinical researcher, who lawfully processes the sensitive data to produce an aggregated statistical result, and a third party (usually several verifiers) assigned to verify this result for reliability and transparency reasons. Our solution guarantees that these verifiers only learn about the aggregated results (and what can be inferred from those about the underlying private data) and nothing more. By taking advantage of the particular scenario at hand (where certain interme-diate results, e.g., the mean over the dataset, are available in the clear) and utilizing secret sharing primitives, our approach turns out to be practically efficient, which we underpin by performing several experiments on real patient data. Our results show that the privacy-preserving verification of the most commonly used statistical operations in clinical research presents itself as an important use case, where the concept of secure multi-party computation becomes employable in practice. 1
(Invited) Ge-on-Insulator MOSFETs for High-Performance and 3D-LSI Applications (2014)

Ge-on-insulator (GeOI) MOSFET structures are advantageous to suppress off-state current levels while keeping the high-performance originated from the high electron and hole mobility. On the other hand, the low thermal budget of the fabrication processes could provide another opportunity for Ge devices. Sequentially stackable COMS devices may be a possible application for 3D-LSIs. In this paper, electrical properties and processes of strained Ge nanowire pMOSFETs and strained GeOI nMOSFETs for high performance applications are presented. Ultra-high hole mobility of over 1900 cm2/Vs and 4-times enhancement of the nMOSFET drive current are demonstrated for the p- and nMOSFETs, respectively. Poly-Ge trigate p- and nFETs on buried oxide (SiO 2 ) layers are also presented for 3D-LSIs. Reasonable operation of sub-100 nm devices and improvement of the current drivability are demonstrated.
Virologic Efficacy of Casirivimab and Imdevimab COVID-19 Antibody Combination in Outpatients With SARS-CoV-2 Infection (2022)

ClinicalTrials.gov Identifier: NCT04666441.
Assemblies of artificial photosynthetic reaction centres (2012)

Nature harnesses solar energy for photosynthesis in which one reaction centre is associated with a number of light harvesting units. The reaction centre and light-harvesting units are assembled by non-covalent interactions such as hydrogen bonding and π–π interactions. This article presents various strategies to assemble artificial photosynthetic reaction centres composed of multiple light harvesting units and charge-separation units, which are connected by non-covalent bonding as well as covalent bonding. First light-harvesting units are assembled on alkanethiolate-monolayer-protected metal nanoparticles (MNPs), which are connected with electron acceptors by non-covalent bonding. Light-harvesting units can also be assembled using dendrimers and oligopeptides to combine with electron acceptors by π–π interactions. The cup-shaped nanocarbons generated by the electron-transfer reduction of cup-stacked carbon nanotubes have been functionalized with a number of porphyrins acting as light-harvesting units as well as electron donors. In each case, the photodynamics of assemblies of artificial photosynthetic reaction centres have revealed efficient energy transfer and electron transfer to afford long-lived charge-separated states.
Coding and Conformational Properties of Oligonucleotides Modified with the Carcinogen N -2-Acetylaminofluorene (1970)

The present studies were undertaken to determine the mechanism by which attachment of the carcinogen N-2-acetylaminofluorene to guanosine residues in nucleic acids distors their structure and function. Oligonucleotides were modified with N-acetoxy-2-acetylaminofluorene, repurified, and their base compositions analyzed. Evidence is presented that acetylaminofluorene residues bound to guanosines in GpUpU, ApApG, or poly (U,G) inactivates their function in codon recognition. Circular dichroism spectra suggest that this is caused by gross conformational changes in these compounds involving both a rotation about the glycosidic bond of guanosine residues bearing N-2-acetylaminofluorene, as well as stacking interactions between the drug and bases adjacent to the substituted guanosine.
Properties Of Clipped Laser Speckle (1985)

The technique of clipping is applied to speckle intensity correlation. With clipping the speckle intensity is converted to a binary signal by comparing the speckle intensity to a fixed threshold. The magnitude of the space-time correlation coefficient is determined from measurements of the correlation function of the clipped speckle. The results of experiments performed using a 2-D clipping detector are presented.
Creation of a locus-specific database for AIP mutations (2013)

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
Genetic linkage map of human chromosome 7 with 63 DNA markers. (1987)

High-density genetic maps of individual human chromosomes will permit accurate localization of disease-associated genes and provide signposts that will be useful in the construction of physical maps. We have constructed a genetic map of chromosome 7 with 63 polymorphic DNA markers by using segregation data from 23 three-generation families and recently developed multilocus linkage-analysis techniques. The map spans 250 centimorgans in females and 170 centimorgans in males, with much of the difference being concentrated in a few intervals. The density and informativeness of the markers are such that there is a high probability of detecting linkage to any disease gene on this chromosome for which 20 phase-known meioses are available.
Mapocho 42K, Santiago, Chile: Equipo Mapocho 42k, 2013 (2013)

El borde de un río urbano es el objeto de esta propuesta que asocia gran escala y economía de medios: plantea la construcción de una continuidad de magnitud geográfica a partir de la introducción de pequeñas piezas de mobiliario urbano y un único criterio de plantaciones arbóreas y pavimentos.
125I-Labeled Peptide Mapping and High-Performance Liquid Chromatography I-Peptide Separation of Protein I of Four Strains of

Neisseria Gonorrhoeae (1983)

Abstract 125I-labeled α-chymotryptic peptides of the principal outer membrane proteins (P.Is) of four strains of Neisseria gonorrhoeae were separated and visualized by two-dimensional (2-D) 125I-peptide mapping and by high-performance liquid chromatography (HPLC) coupled with a Beckman Biogamma counter. In addition, 125I-peptides were recovered from the HPLC separation and re-separated by the 2-D 125I-peptide mapping system. The results indicated that the 2-D 125I-peptide mapping procedure was best suited for comparative analyses of α-chymotryptic digests whereas the HPLC system, which is able to detect many more peptides than the 2-D system, is ideally suited for preparative separation of the 125I-peptides. 125I-peptides separated by HPLC could be recovered, rerun on the 2-D system, and the location of each peptide ascertained. The coupling of these two procedures allows for the isolation of specific 125I-labeled peptides for further immunological and structural analyses of these outer membrane proteins.
Automated detection and classification of patient–ventilator asynchrony by means of machine learning and simulated data (2023)

In the future, these algorithms can be utilized to gain a better understanding of the clinical impact of PVAs and help clinicians to better monitor their ventilation strategies.