gebhart/patrepeval huggingface dataset:
Cemented paste backfill strength profiles for continuous pouring and liquefaction resistance (2023)

Current practice for backfilling tall stopes (e.g., long hole or Alimak) with cemented paste backfill (CPB) involves an initial plug pour to protect the barricade, followed by a main pour for the remaining stope. Many mines use higher binder content in the plug to accelerate curing time, supporting continuous pouring (i.e., no plug cure time before starting the main pour). An analytical solution to assess the required plug strength for continuous pours was recently proposed in a paper by Grabinsky et al. (2021). Similarly, various heuristics have been published suggesting a minimum Unconfined Compressive Strength will be sufficient to prevent CPB liquefaction under even the most implausible extreme loading events. However, practising mining engineers would benefit from a more straightforward design approach to assess the suitability of their backfill’s evolving strength in continuous pour and liquefaction resistance design issues. To this end, the authors have found it useful to consider the concept of a Strength Profile with depth in the plug, recognising that this Strength Profile is transient (i.e., changing with time) and must be considered for different critical stages of the plug pour and main pour. The Strength Profile design concept is explained in this paper and demonstrated using key case histories from mines where the backfill was previously monitored during continuous pouring and where the backfill materials were extensively characterised in the laboratory.
Optimisation of rotorcraft fuel tank for crashworthiness based on a neural network (2016)

Crashworthy fuel tank has been widely implemented among rotorcraft, and they have served a valuable contribution to improving the survivability of crews and passengers. From the early stages of military rotorcraft history, the US Army has developed and implemented a detailed military specification documenting the unique crashworthiness requirements for rotorcraft fuel tank with the aim of reducing the high incidence of fatalities due to post-crash fires. International manufacturers have followed this information to develop their own fuel tank, and have reflected the results of crash impact tests in trial-and-error design and manufacturing processes. Since the crash impact test itself requires lengthy preparation together with costly fuel cell specimens, a series of numerical simulations of the crash impact test with digital mock-ups is necessary, even at the early design stage, in order to minimise trial-and-error testing with full-scale fuel tank. In this study, a number of numerical simulations on fuel cell crash impact tests are performed with the crash simulation software, ANSYS/Autodyn. The resulting equivalent stresses are further analysed to evaluate a number of appropriate design parameters and the artificial neural network and simulated annealing method are simultaneously implemented to optimise the crashworthy performance of fuel tank.
Effects of Surface Morphology on the Anchoring and Electrooptical Dynamics of Confined Nanoscale Liquid Crystalline Films (2002)

The orientation and dynamics of two 40-nm thick films of 4-n-pentyl-4'-cyanobiphenyl (5CB), a nematic liquid crystal, have been studied using step-scan Fourier transform infrared spectroscopy (FTIR). The films are confined in nanocavities bounded by an interdigitated electrode array (IDA) patterned on a zinc selenide (ZnSe) substrate. The effects of the ZnSe surface morphology (specifically, two variations of nanometer-scale corrugations obtained by mechanical polishing) on the initial ordering and reorientation dynamics of the electric-field-induced Freedericksz transition are presented here. The interaction of the 5CB with ZnSe surfaces bearing a spicular corrugation induces a homeotropic (surface normal) alignment of the film confined in the cavity. Alternately, when ZnSe is polished to generate fine grooves along the surface, a planar alignment is promoted in the liquid crystalline film. Time-resolved FTIR studies that enable the direct measurement of the rate constants for the electric-field-induced orientation and thermal relaxation reveal that the dynamic transitions of the two film structures are significantly different. These measurements quantitatively demonstrate the strong effects of surface morphology on the anchoring, order, and dynamics of liquid crystalline thin films.
A meta-analysis on neural changes of cognitive training for mental disorders in executive function tasks: increase or decrease brain activation? (2022)

CT improves cognitive function by supporting language and memory function, and reducing neuronal resources associated with basic visual processing.
Magnetic behavior of Y-Ba-Cu-O superconductors prepared under different oxygen anneals (1988)

In our study of three YBa2 Cu3 oxides prepared with different oxygen anneals, we observed that the temperature derivative of the magnetization or susceptibility χ(T) of these high-Tc superconductors has a maximum at approximately the transition temperature, Tc . This temperature as estimated by the peak value of (∂χ/∂T)H , ranged between 55 and 65 K. The most oxygen-poor sample showed the lowest Tc and the most oxygen-rich sample showed the highest Tc . In the subcritical region, a novel irreversibility is observed in the field-cooled warm-up and cool-down behaviors.
Recent Advances in the Management of Mucormycosis: From Bench to Bedside (2009)

Recent therapeutic advances have the potential to improve outcomes of mucormycosis. Lipid formulations of amphotericin B (LFAB) have evolved as the cornerstone of primary therapy for mucormycosis. Posaconazole may be useful as salvage therapy, but it cannot be recommended as primary therapy for mucormycosis on the basis of available data. Preclinical and limited retrospective clinical data suggest that combination LFAB-echinocandin therapy may improve survival during mucormycosis. A definitive trial is needed to confirm these results. Combination therapy with LFAB and the iron chelator, deferasirox, also improved outcomes in animal models of mucormycosis. In contrast, combination polyene-posaconazole therapy was of no benefit in preclinical studies. Adjunctive therapy with recombinant cytokines, hyperbaric oxygen, and/or granulocyte transfusions can be considered for selected patients. Early initiation of therapy is critical to maximizing outcomes; recent developments in polymerase chain reaction technology are advancing early diagnostic strategies. Prospective, randomized clinical trials are needed to define optimal management strategies for mucormycosis.
Precision Temperature Measurement Using CMOS Substrate PNP Transistors (2004)

This paper analyzes the nonidealities of temperature sensors based on substrate pnp transistors and shows how their influence can be minimized. It focuses on temperature measurement using the difference between the base-emitter voltages of a transistor operated at two current densities. This difference is proportional to absolute temperature (PTAT). The effects of series resistance, current-gain variation, high-level injection, and the Early effect on the accuracy of this PTAT voltage are discussed. The results of measurements made on substrate pnp transistors in a standard 0.5-/spl mu/m CMOS process are presented to illustrate the effects of these nonidealities. It is shown that the modeling of the PTAT voltage can be improved by taking the temperature dependency of the effective emission coefficient into account using the reverse Early effect. With this refinement, the temperature can be extracted from the measurement data with an absolute accuracy of /spl plusmn/0.1/spl deg/C in the range of -50 to 130/spl deg/C.
Multimodal x-ray and electron microscopy of the Allende meteorite (2019)

Multimodal microscopy that combines complementary nanoscale imaging techniques is critical for extracting comprehensive chemical, structural, and functional information, particularly for heterogeneous samples. X-ray microscopy can achieve high-resolution imaging of bulk materials with chemical, magnetic, electronic, and bond orientation contrast, while electron microscopy provides atomic-scale spatial resolution with quantitative elemental composition. Here, we combine x-ray ptychography and scanning transmission x-ray spectromicroscopy with three-dimensional energy-dispersive spectroscopy and electron tomography to perform structural and chemical mapping of an Allende meteorite particle with 15-nm spatial resolution. We use textural and quantitative elemental information to infer the mineral composition and discuss potential processes that occurred before or after accretion. We anticipate that correlative x-ray and electron microscopy overcome the limitations of individual imaging modalities and open up a route to future multiscale nondestructive microscopies of complex functional materials and biological systems.
The Effect of Various Postphlebotomy Storage Conditions on Drug Levels (1988)

Monitoring drug levels in patients is standard practice in presentday critical care medicine. Clinical laboratories, however, are often unable to assay drug levels immediately following phlebotomy. This may result in blood samples being kept under a variety of storage conditions for nonuniform periods of time. The current study evaluated the stability of eight frequently monitored medications and one of their metabolities, in whole blood and plasma, at 4 degrees C or 25 degrees C, for up to 72 hours. The drugs included antibiotics, a bronchodilator, antiarrhythmics, and an anticonvulsant. Significant changes in drug levels were not identified at the time points studied. Our data suggests that meticulous postphlebotomy handling of blood samples may not be essential to obtain accurate levels of the drugs studied.
Pulsed Electroreduction of  CO 2 on Silver Electrodes (1996)

A large degree of selectivity of reduction products of has been achieved on Ag electrodes by a pulsed technique in which the anodic (Va) and the cathodic (Vc) bias were found to be key parameters. The maximum faradaic efficiencies for CO, , and were, respectively, 70% (Vc = −2.0 V, Va = −0.125 V), 55% (−2.25 V, −0.4 V), 3.1% (−2.25 V, −0.4 V), 3.1% (−2.25 V, −0.4 V), and 22% (−2.25 V, −0.5 V). The total value of 58.1% for and formation recorded on the Ag electrode is comparable with that for and formation on the Cu electrode, which has long been considered as a unique metal for and formation. In addition, in the potential range where and are preferentially produced, the formation of HCOOH was found to be almost zero. The selectivity was ascribed to be due to the extent of the surface coverage of adsorbed hydrogen, which can be controlled by the anodic bias.
High Dynamic Range Fiber Optic Link Measurements With Traveling Wave Linearized Directional Coupler Modulators* (1993)

An important figure of merit for all high frequency analog transmission links is the spur free dynamic range (SFDR) which is the ratio of the largest to smallest signal that the link can transmit and receive without introducing distortion. The two factors which limit the dynamic range in fiber optic links are the system noise, predominantly from the laser relative intensity noise and the photodetector shot noise, and the non-linearity of the modulation process. The noise level of fiber optic systems has been reduced as much as possible for now through the use of high-power solid state or DFB lasers and attention has turned to improving the linearity of the modulation.
Association between the body weight of growing pigs and the functional capacity of their gut microbiota (2020)

Gastrointestinal microbiota impact host's biological activities, including digestion of indigestible feed components, energy harvest, and immunity. In this study, fecal microbiota of high body weight (HW) and low body weight (LW) growing pigs at 103 days of age were compared. Principal coordinates analysis separated the HW and LW groups into two clusters, indicating their potential differences between microbial community composition. Although the abundances of two major phyla, Firmicutes and Bacteroidetes, did not significantly differ between the HW and LW groups, some genera showed significant differences. Among them, Peptococcus and Eubacterium exhibited strong positive correlations with body weight (BW) and average daily gain (ADG) (Rho > 0.40), whereas Treponema, Desulfovibrio, Parabacteroides, and Ruminococcaceae_unclassified exhibited strong negative correlations with BW and ADG (Rho < -0.40). Based on these results, the structure of intestinal microbiota may affect growth traits in pigs through host-microbe interactions. Further in-depth studies will provide insights into how best to reshape host-microbe interactions in pigs and other animals as well.
Parametric Analysis of Tradeoffs Between Transient and Steady-State Loss Reduction for Induction Machines of Different Sizes (2019)

Conventional induction machine design generally focuses on steady-state loss reduction under constant rated flux. Transient loss reduction under flux manipulation during torque transients has not been well addressed in the design process in the literature. This paper investigates the design tradeoffs between transient and steady-state loss reduction in terms of induction machine equivalent circuit parameters. The total transient loss is further separated into accumulated steady-state loss and the energy consumption to change the rotor flux state (RFS). The parametric design tradeoffs between transient and steady-state loss reduction are first conducted on a traction size induction machine for torque transients during the UDDS driving cycle. The manipulation of machine equivalent circuit parameters to reduce transient losses without increasing steady-state losses is studied. The design tradeoffs are then conducted for a 3HP induction machine.
Genomic and Protein Structural Maps of Adaptive Evolution of Human Influenza A Virus to Increased Virulence in the Mouse (2011)

Adaptive evolution is characterized by positive and parallel, or repeated selection of mutations. Mouse adaptation of influenza A virus (IAV) produces virulent mutants that demonstrate positive and parallel evolution of mutations in the hemagglutinin (HA) receptor and non-structural protein 1 (NS1) interferon antagonist genes. We now present a genomic analysis of all 11 genes of 39 mouse adapted IAV variants from 10 replicate adaptation experiments. Mutations were mapped on the primary and structural maps of each protein and specific mutations were validated with respect to virulence, replication, and RNA polymerase activity. Mouse adapted (MA) variants obtained after 12 or 20-21 serial infections acquired on average 5.8 and 7.9 nonsynonymous mutations per genome of 11 genes, respectively. Among a total of 115 nonsynonymous mutations, 51 demonstrated properties of natural selection including 27 parallel mutations. The greatest degree of parallel evolution occurred in the HA receptor and ribonucleocapsid components, polymerase subunits (PB1, PB2, PA) and NP. Mutations occurred in host nuclear trafficking factor binding sites as well as sites of virus-virus protein subunit interaction for NP, NS1, HA and NA proteins. Adaptive regions included cap binding and endonuclease domains in the PB2 and PA polymerase subunits. Four mutations in NS1 resulted in loss of binding to the host cleavage and polyadenylation specificity factor (CPSF30) suggesting that a reduction in inhibition of host gene expression was being selected. The most prevalent mutations in PB2 and NP were shown to increase virulence but differed in their ability to enhance replication and demonstrated epistatic effects. Several positively selected RNA polymerase mutations demonstrated increased virulence associated with >300% enhanced polymerase activity. Adaptive mutations that control host range and virulence were identified by their repeated selection to comprise a defined model for studying IAV evolution to increased virulence in the mouse.
Performance analysis and iterative decoding of I-Q trellis space-time codes (2006)

I-Q trellis codes are known to increase the time diversity of coded systems. When I-Q codes are used with multiple transmit antennas, the decoding and performance evaluation requires the construction of the high-complexity super-trellis of the component codes. In the paper, the bit error probability and the design criteria of I-Q ST codes are derived using the transfer functions of the component codes. Conditions for the geometrical uniformity of I-Q space-time (ST) codes are derived from the geometrical uniformity of the component codes. In addition, a low-complexity iterative receiver for I-Q ST codes is presented. The receiver essentially performs iterative detection and decoding. Results show that three iterations of the iterative receiver performs very close to the optimal decoding.
T cells from eosinophilic patients produce interleukin-5 with interleukin-2 stimulation (1989)

Anti-murine (m) interleukin-5 (IL-5) antibody was found to inhibit eosinophil (Eo) colony formation stimulated by recombinant human (rh) IL-5, but did not inhibit the production of Eo stimulated by rh IL-3 or granulocyte-macrophage colony-stimulating factor (GM-CSF). Conditioned medium (CM) prepared from eosinophilic patients' T cells with interleukin-2 (IL-2) stimulation (T-IL-2-CM), was found to contain CFU- Eo growth-stimulating factor. Using anti-mIL-5 antibody, we demonstrated that T-IL-2-CM from patients with eosinophilia contained a significant amount of IL-5. We also detected IL-5 mRNA in T cells from eosinophilic patients with IL-2 stimulation. These results suggest that IL-5 plays an important role in the induction of selective eosinophilia in humans and that IL-5 is produced from T cells with IL-2 stimulation.
Functional Acetabular Orientation Varies Between Supine and Standing Radiographs: Implications for Treatment of Femoroacetabular Impingement (2015)

The functional orientation of the acetabulum varies between supine and standing radiographs and must be considered when diagnosing and treating patients with symptomatic FAI. Standing pelvic orientation results in posterior pelvic tilt and later occurrence of FAI in the arc of motion. Although we cannot recommend standing radiographs on the current study alone, we do recommend larger studies to determine whether any significant differences truly exist.
A New Animal Model Utilizing Multimodal Immunosuppression for Laboratory Chemosensitivity Testing of Human Bladder Carcinoma Tumor Xenografts (1987)

No AccessJournal of Urology1 Jun 1987A New Animal Model Utilizing Multimodal Immunosuppression for Laboratory Chemosensitivity Testing of Human Bladder Carcinoma Tumor Xenografts Steven C. Flashner, Susan H.M. Poulton, and Philip J. Walther Steven C. FlashnerSteven C. Flashner More articles by this author , Susan H.M. PoultonSusan H.M. Poulton More articles by this author , and Philip J. WaltherPhilip J. Walther More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)75243-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "A New Animal Model Utilizing Multimodal Immunosuppression for Laboratory Chemosensitivity Testing of Human Bladder Carcinoma Tumor Xenografts." The Journal of Urology, 137(6), p. 127A © 1987 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 137Issue 6June 1987Page: 127A Advertisement Copyright & Permissions© 1987 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Steven C. Flashner More articles by this author Susan H.M. Poulton More articles by this author Philip J. Walther More articles by this author Expand All Advertisement Loading ...
Supplementary Table 2 from MYC Phosphorylation at Novel Regulatory Regions Suppresses Transforming Activity (2023)

&lt;p&gt;XLS file, 2439K, MYC ChIP-on-chip data in MCF10A cells.&lt;/p&gt;
Design of a Highly-Efficient Light Guide Plate for the Edge Lighting Backlight Module (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
The Role of Calmodulin in Regulation of Glycogen Metabolism (1979)

Conference Article| August 01 1979 The Role of Calmodulin in Regulation of Glycogen Metabolism DENNIS B. RYLATT; DENNIS B. RYLATT 1Department of Biochemistry, University of Dundee, Dundee DD1 4HN, Scotland, U.K. Search for other works by this author on: This Site PubMed Google Scholar NOOR EMBI; NOOR EMBI 1Department of Biochemistry, University of Dundee, Dundee DD1 4HN, Scotland, U.K. Search for other works by this author on: This Site PubMed Google Scholar PHILIP COHEN PHILIP COHEN 1Department of Biochemistry, University of Dundee, Dundee DD1 4HN, Scotland, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1979) 7 (4): 622–624. https://doi.org/10.1042/bst0070622 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation DENNIS B. RYLATT, NOOR EMBI, PHILIP COHEN; The Role of Calmodulin in Regulation of Glycogen Metabolism. Biochem Soc Trans 1 August 1979; 7 (4): 622–624. doi: https://doi.org/10.1042/bst0070622 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1979 Biochemical Society1979 Article PDF first page preview Close Modal You do not currently have access to this content.
Epitaxial Boron-Doped Emitter by CVD for Rear Junction n-Type Solar Cells (2009)

Epitaxial boron-doped emitters by CVD can provide a valuable alternative to the use of aluminum or diffused boron for the creation of p-type emitters. Compared to the traditional boron-diffusion emitters for high-efficiency cells, epitaxial emitters need shorter process time, no boron skin removal step and have more opportunities to optimize the emitter doping profile. Our work proves that epitaxial emitters can be a good alternative for p-type emitter. Very promising cell results with the highest cell efficiency of 16.8 % under 1 Sun have been achieved. Good fill factors have been obtained which indicate good metal contacts are obtained on the epitaxial emitter. Cell results of first tests on FZ n-type material are very encouraging and indicate a high potential of such epitaxial emitters for rear junction n-type solar cells.