gebhart/patrepeval huggingface dataset:
Fabrication and Electrocatalysis of Self-Assembly Directed Gold Nanoparticles Anchored Carbon Nanotubes Modified Electrode (2006)

A self-assembly directed approach was adopted to modify glassy carbon electrode (GC) with gold nanoparticles incorporation and the electrocatalytic performance of self-assembly modified electrode, GC/SA-Au-ME was critically evaluated for the oxidation of ascorbic acid (AA). The modification involves the dispersion of multi-wall carbon nanotube (MWNT) and an inclusion complex, beta-cyclodextrin-4-aminothiophenol on the surface of GC electrode in the presence of cetyltrimethylammonium bromide (CTAB). Gold nanoparticles were deposited into the self-assembled sites to fabricate the modified electrode, GC/SA-Au-ME. Another electrode (GC-Au-ME) was fabricated under similar conditions in the absence of CTAB. The electrocatalytic activity of the modified electrodes (GC/SA-Au-ME and GC-Au-ME) towards the oxidation of AA was critically compared. Cyclic voltammetry, chronoamperometry, and double potential chronoamperometry were used to evaluate the characteristics of the modified electrodes. The self-assembled electrode (GC/SA-Au-ME) shows excellent electrocatalytic activity over the other electrode, GC-Au-ME. Augmented current response, faster electron transfer kinetics (with a rate constant for electron transfer process as 3.25 x 10(4) cm3 mol(-1) s(-1)), linear range of response for the analyte (1-50 mM with an extended detection limit to 1 microM), better sensitivity, and selectivity were witnessed for the self-assembly directed modified electrode.
Water relations of lettuce seed thermoinhibition. II. Ethylene and endosperm effects on base water potential (1994)

Abstract A water relations (hydrotime) model was employed to characterize the responses of lettuce ( Lactuca sativa L.) seed germination to temperature, water potential (ψ), endosperm disruption, and the ethylene precursor 1-aminocyclopropane-1-carboxylic acid (ACC). The base water potentials (ψ b ), standard deviations of base water potential and hydrotime constants (θ H ) estimated by the model were used to predict the germination rates at reduced ψ and supraoptimal temperatures in the presence or absence of ACC. The distribution of ψ b values among seeds in the population (ψ b ( g )) increased (became more positive) as the imbibition temperature increased, indicating a greater sensitivity of seeds to reduced ψ at thermoinhibitory temperatures. Slitting the seeds at the cotyledonary end to disrupt the integrity of the endosperm extended the high temperature range for germination and maintained lower ψ b ( g ) distributions compared with intact seeds as temperature increased. ACC (10 m m ) in the imbibition solution raised the upper temperature limit for germination by about 2°C, and also lowered ψ b ( g ) values by 0.1 to 0.2 MPa. The effect of ACC on ψ b ( g ) was more pronounced at higher imbibition temperatures and in slit seeds. ACC (via conversion to ethylene) extends the high temperature limit for lettuce seed germination by acting in the embryo to maintain a lower ψ threshold for the initiation of growth as temperature increases. Evidence from other species as well suggests that this may be a general mechanism for the action of ethylene in promoting seed germination.
A 1.5mW 1MSPS 16bit SAR ADC with high performance (2012)

Analog-to-Digital converter (ADC) based on successive approximation (SAR) are limited in their noise performance. Noise sources such as the sampling noise or the comparator noise can only be reduced with increasing the die size or increasing the power consumption. The only way to achieve compatible effective number of bits is to keep the signal range high. 16bit SAR ADCs are therefore typically designed with 0–5V input voltage ranges and therefore use 5V processes since 15 years. Many circuit techniques have been implemented such as [1, 2, 3] to reduce the power consumption, but these ADCs will finally be limited by the digital power dissipation. A novel dual CDAC architecture was developed to overcome these constraints. 5V transistors are only required for analog input and reference switches. The analog circuitry of the ADC can run from a significantly lower supply voltage with all advantages of modern processes. A test chip was implemented with the help of the Bavarian Research Foundation (BFS).
Quantum Correlations and Classical Resonances in an Open Chaotic System (2001)

We show that the autocorrelation of quantum spectra of an open chaotic system is well described by the classical Ruelle-Pollicott resonances of the associated chaotic strange repeller. This correspondence is demonstrated utilizing microwave experiments on 2-D n-disk billiard geometries, by determination of the wave-vector autocorrelation C(\kappa) from the experimental quantum spectra S_{21}(k). The correspondence is also established via "numerical experiments" that simulate S_{21}(k) and C(\kappa) using periodic orbit calculations of the quantum and classical resonances. Semiclassical arguments that relate quantum and classical correlation functions in terms of fluctuations of the density of states and correlations of particle density are also examined and support the experimental results. The results establish a correspondence between quantum spectral correlations and classical decay modes in an open systems.
New Ethacrynic Acid Derivatives as Potent Cytoskeletal Modulators in Trabecular Meshwork Cells (2004)

A series of ethacrynic acid (ECA) derivatives were synthesized and examined for ocular hypotensive activity. Efficacy was evaluated in a cell-shape assay, using human trabecular meshwork cells, and cytotoxicity in a (3-(4,5-dimethylthiazole-2-yl)-5-(3-carboxymethoxy phenyl)-2-(4-sulfophenyl)-2H-tetrazolium) assay, using cultured bovine trabecular meshwork cells. Many of the derivatives demonstrated efficacy equal to or greater than that of ECA. SA9000 was selected as the most promising candidate for a novel ocular hypotensive drug with few side effects.
Assessment of menthol mint collection for genetic variability and monoterpene biosynthetic potential (2009)

Abstract Eighteen accessions of Mentha arvensis var. piperascens Holmes from the CIMAP collection (CIMAP/C01 to CIMAP/C18) consisting of wild collections and released varieties, their mutants, seed progeny and hybrids from the CIMAP gene bank were assessed for diversity through a combined morphochemical and molecular approach. Morphological characters, oil yield and essential oil components were taken into account to generate a cluster that outgrouped accession CIMAP/C05 from others. A total of 60 primers were used for RAPD and the tree generated after cluster analysis revealed accession CIMAP/C05 as the most diverse genotype. All the accessions exhibited differences in narrow range except CIMAP/C05. A wide range of compositional differences were observed in the essential oil profile of the genotypes indicating varying efficiencies of conversion of one component into other and/or existing metabolic blocks in the essential oil biosynthetic pathway in them. Copyright © 2009 John Wiley &amp; Sons, Ltd.
Industrial Results of Alglass FH Oxy Fuel Forehearth Burner Operation (2009)

This chapter contains sections titled: Introduction The Alglass FH Technology Procedure Results Conclusions
New opportunities for load balancing in network-wide intrusion detection systems (2012)

As traffic volumes and the types of analysis grow, network intrusion detection systems (NIDS) face a continuous scaling challenge. Management realities, however, limit NIDS hardware upgrades to occur typically once every 3-5 years. Given that traffic patterns can change dramatically, this leaves a significant scaling challenge in the interim. This motivates the need for practical solutions that can help administrators better utilize and augment their existing NIDS infrastructure. To this end, we design a general architecture for network-wide NIDS deployment that leverages three scaling opportunities: on-path distribution to split responsibilities, replicating traffic to NIDS clusters, and aggregating intermediate results to split expensive NIDS processing. The challenge here is to balance both the compute load across the network and the total communication cost incurred via replication and aggregation. We implement a backwards-compatible mechanism to enable existing NIDS infrastructure to leverage these benefits. Using emulated and trace-driven evaluations on several real-world network topologies, we show that our proposal can substantially reduce the maximum computation load, provide better resilience under traffic variability, and offer improved detection coverage.
Real-time 46 Gb/s Coherent System (2008)

Continuous real-time measurements of coherent 46 Gb/s transmission with Dual Polarization QPSK. Digital compensation is used for dispersion and polarization effects, with little performance degradation created by 150 ps of rapidly varying 1st-order PMD.
Experimental evidence of Bloch surface waves on photonic crystals with thin-film LiNbO_3 as a top layer (2017)

Strong nonlinear, electro-optical, and thermo-optical properties of lithium niobate (LN) have gained much attention. However, the implementation of LiNbO3 in real devices is not a trivial task due to difficulties in manufacturing and handling thin-film LN. In this study, we investigate an optical device where the Bloch surface wave (BSW) propagates on the thin-film LN to unlock its properties. First, access to the LN film from air (or open space) is important to exploit its properties. Second, for sustaining the BSW, one-dimensional photonic crystal (1DPhC) is necessary to be fabricated under the thin-film LN. We consider two material platforms to realize such a device: bulk LN and commercial thin-film LN. Clear reflectance dips observed in far-field measurements demonstrate the propagation of BSWs on top of the LN surface of the designed 1DPhCs.
Phosphate Separation and Recovery from Wastewater by Novel Electrodialysis (2013)

Stimulated by the depletion of phosphate resources, phosphate recovery systems have been studied in recent years. The use of struvite reactors has proven to be an effective phosphate recovery process. However, the struvite reactor effluent still consists of an excessive amount of phosphate that cannot be recovered nor can be directly discharged. In this study, selectrodialysis (SED) was used to improve the efficiency of phosphate recovery from a struvite reactor: SED was implemented in such a way that phosphate from the effluent of an USAB (upflow anaerobic sludge blanket) reactor was transferred to the recycled effluent of a struvite reactor. Prior to the experiments, synthetic water with chloride and phosphate was used to characterize the efficiency of SED for phosphate separation. Results indicate that SED was successful in concentrating phosphate from the feed stream. The initial current efficiency reached 72%, with a satisfying (9 mmol L(-1)) phosphate concentration. In the experiments with the anaerobic effluent as the phosphate source for enrichment of the effluent of the struvite reactor, the phosphate flux was 16 mmol m(-2) h(-1). A cost evaluation shows that 1 kWh electricity can produce 60 g of phosphate by using a full scale stack, with a desalination rate of 95% on the feed wastewater. Finally, a struvite precipitation experiment shows that 93% of phosphate can be recovered. Thus, an integrated SED-struvite reactor process can be used to improve phosphate recovery from wastewater.
A-Priori Calibration of a Structured Light Underwater 3D Sensor (2020)

In this study, we introduce a new calibration method for underwater optical stereo scanners. It uses air calibration, additional underwater parameters, and extended camera modeling. The new methodology can be applied to both passive photogrammetric and structured light three-dimensional (3D) scanning systems. The novel camera model uses a variable principal distance depending on the radial distance to the principal point instead of two-dimensional distortion functions. This allows for an initial improvement of 3D reconstruction quality. In a second step, certain underwater-specific parameters—such as refraction indices, glass thickness, and view-port distances—are determined. Finally, a correction function for the entire measurement volume can be obtained from a few underwater measurements. Its application further improves the measurement accuracy. Measurement examples show the performance of the new calibration method in comparison to current underwater calibration strategies. A discussion of the possibilities and limits of the new calibration method and an outlook for future work complete this work.
P2‐039: PROGRESS OF THE PHASE I CLINICAL TRIAL TO EVALUATE LONGEVERON ALLOGENEIC MESENCHYMAL STEM CELLS (LMSCS) AS A POTENTIAL THERAPEUTIC FOR ALZHEIMER'S DISEASE (2019)

The pathological consequences of Alzheimer's disease (AD) are complex, and include beta-amyloid deposition, a proinflammatory state, and neurovascular disruption. In order to effectively treat AD, it will be essential to target these multiple pathological features. Mesenchymal stem cells (MSCs) have pleiotropic mechanisms of action (MOAs) that make them highly attractive therapeutic candidates for AD. Specifically, MSCs have powerful anti-inflammatory properties, improve vascular functioning, and promote beta-amyloid clearance in preclinical AD studies, among other relevant MOAs. In this study, we are investigating the therapeutic potential of a proprietary formulation of MSC, called Longeveron Mesenchymal Stem Cells (LMSCs), for treating AD. We are conducting a double-blinded, randomized, placebo-controlled clinical trial Phase I clinical trial to investigate the safety and provisional efficacy of LMSCs to treat AD. This clinical study is under oversight by FDA, an IRB, and an independent Data Monitoring Safety Board (DSMB), and is registered under ClinicalTrials.gov (NCT02600130). Each enrolled subjects has clinically-diagnosed mild AD, with confirmatory MRI and PET scan for beta-amyloid. Subjects are randomized to receive a single intravenous infusion of 20 million LMSCs (low-dose), 100 million LMSCs (high-dose), or placebo. The subjects are evaluated for 1 year post-treatment for changes in cognitive assessments, patient-reported outcomes (PROs), and biomarkers (serum, CSF, and MRI). This multi-year trial is proceeding ahead of schedule, with full-enrollment projected by the third quarter of 2019. The safety run-in phase of this study has been completed, reviewed by the DSMB, and the DSMB has recommended the trial continue without modification. No serious adverse events (SAEs) have occurred that are attributable to the LMSCs. The second phase of the trial is actively enrolling. Preliminary data suggest the utility of biomarker analyses to follow that trajectory in the study subjects, including blood biomarkers and brain volumetry via MRI. Our data supports the high safety and tolerability of LMSC in subjects with mild-AD. Efficacy data is not yet available due to the study blind. However, technical ability to rigorously test endpoints is demonstrated. We thank the Alzheimer's Association for supporting this research through the Part the Cloud Challenge on Neuroinflammation grant award #PTC C-16-422443.
Anatomic shoulder replacement for primary osteoarthritis in patients over 80 years (2015)

Good to excellent results can be expected after anatomic TSA in patients over the age of 80. Our findings suggest that they have similar results to those in patients around 70 years of age.
Gapmer Antisense Oligonucleotides Targeting 5S Ribosomal RNA Can Reduce Mature 5S Ribosomal RNA by Two Mechanisms (2020)

In this study, we demonstrate that 5S ribosomal RNA (rRNA), a highly structured and protein-bound RNA, is quite difficult to reduce with antisense oligonucleotides (ASOs). However, we found a single accessible site that was targetable with a high-affinity complementary ASO. The ASO appeared to bind to the site, recruit RNaseH1, and cause degradation of the 5S RNA. Intriguingly, we also observed that the same ASO induced an accumulation of pre-5S RNA, which may contribute to reduced levels of mature 5S rRNA. As expected, ASO mediated reduction of 5S RNA, and modest inhibition of processing of pre-5S RNA resulted in nucleolar toxicity. However, the toxicity induced was minimal compared with actinomycin D, consistent with its modest effects on pre-5S rRNA. Mechanistically, we show that the accumulation of pre-5S rRNA required ASO hybridization to the cognate rRNA sequence but was independent of RNaseH1 activity. We found that Ro60 and La, proteins known to bind misprocessed RNAs, likely sequester the ASO-pre-5S rRNA species and block RNaseH1 activity, thus identifying another example of competitive mechanisms mediated by proteins that compete with RNaseH1 for binding to ASO-RNA heteroduplexes.
Identification of a Curie transition in vinylidene fluoride/tetrafluoroethylene random copolymers by spectroscopic methods (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIdentification of a Curie transition in vinylidene fluoride/tetrafluoroethylene random copolymers by spectroscopic methodsJennifer. Green and J. F. RaboltCite this: Macromolecules 1987, 20, 2, 456–457Publication Date (Print):February 1, 1987Publication History Published online1 May 2002Published inissue 1 February 1987https://pubs.acs.org/doi/10.1021/ma00168a047https://doi.org/10.1021/ma00168a047research-articleACS PublicationsRequest reuse permissionsArticle Views70Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Estimation of travelling wave arrival time in longitudinal differential protections for multi‐terminal HVDC systems (2018)

Multi‐terminal high‐voltage DC (HVDC) systems equipped with HVDC breakers require that detection and clearing of faults occur within a few milliseconds. Although detection without communication is generally preferred with regard to detection delay and simplicity, detection schemes relying on communication can enhance the overall performance due to their reliability. One such principle is the travelling wave differential protection that is based on the comparison of waves at both ends rather than solely on current. However, as with conventional differential protections, some kind of synchronisation must be applied to properly compensate for the time difference between samples obtained at different geographical locations. In this study, a synchronisation algorithm is presented that applies real‐time signal processing to automatically obtain a proper compensation between the signals from both ends. The algorithm is examined by injection of data samples, generated from the simulation of an external fault in a PSCAD/EMTDC model. Additionally, the suitability for a real‐time implementation is evaluated by execution time estimation using a simulated DSP. The algorithm is found to perform well, not only in identifying the compensation delay but also in terms of computational efficiency, thus allowing for real‐time application.
Proton NMR determination of crystallinity in poly(ethylene terephthalate) (1994)

Abstract The results of proton NMR T 1 xz measurements on poly(ethylene terephthalate) (PET) films and fibers processed under various conditions are presented. Consistent with previous results, two domains are found in isotropic, amorphous PET. The NMR results provide an accurate measure of crystallinity in PET films and fibers, without requiring any assumptions about the semi‐crystalline morphology of the polymer. The NMR technique is particularly advantageous for PET fibers where orientation effects interfere with the more traditional density determination of crystallinity.
Associations between Grain Crop Yields in Central-Eastern Argentina and El Niño–Southern Oscillation (1999)

Associations are investigated between yields of major crops in the Argentine Pampas (central-eastern Argentina) and El Niño–Southern Oscillation (ENSO) phase. For maize and sorghum, higher (lower) yield anomalies occur more frequently than expected by chance alone during warm (cold) ENSO events. For both crops, the depression of yields during cold events is, on average, larger and less variable than yield increases are during warm events. A yield decrease during cold events also is observed in soybean yields, although the effect of warm events is not statistically significant. There is a marginally significant tendency for low sunflower yields to occur less frequently than expected during cold events. Wheat, the only winter crop considered, did not show an association with ENSO. Precipitation anomalies during October–February (the period with strongest ENSO signal in the Pampas) are summarized through principal component analysis. Precipitation anomalies during November–January are significantly correlated with maize, sorghum, and soybean yield anomalies. In turn, those precipitation anomalies show a distinct ENSO signal. Late spring–early summer precipitation, then, appears to mediate associations between ENSO phase and yields of maize, sorghum, and soybean in the Pampas.
Elevated level of carbon dioxide affects metabolism and shell formation in oysters Crassostrea virginica (Gmelin) (2010)

Estuarine organisms are exposed to periodic strong fluctuations in seawater pH driven by biological carbon dioxide (CO 2 ) production, which may in the future be further exacerbated by the ocean acidification associated with the global rise in CO 2 . Calcium carbonate-producing marine species such as mollusks are expected to be vulnerable to acidification of estuarine waters, since elevated CO 2 concentration and lower pH lead to a decrease in the degree of saturation of water with respect to calcium carbonate, potentially affecting biomineralization. Our study demonstrates that the increase in CO 2 partial pressure (pCO 2 ) in seawater and associated decrease in pH within the environmentally relevant range for estuaries have negative effects on physiology, rates of shell deposition and mechanical properties of the shells of eastern oysters Crassostrea virginica (Gmelin). High CO 2 levels (pH ~7.5, pCO 2 ~3500 atm) caused significant increases in juvenile mortality rates and inhibited both shell and soft-body growth compared to the control conditions (pH ~8.2, pCO 2 ~380 atm). Furthermore, elevated CO 2 concentrations resulted in higher standard metabolic rates in oyster juveniles, likely due to the higher energy cost of homeostasis. The high CO 2 conditions also led to changes in the ultrastructure and mechanical properties of shells, including increased thickness of the calcite laths within the hypostracum and reduced hardness and fracture toughness of the shells, indicating that elevated CO 2 levels have negative effects on the biomineralization process. These data strongly suggest that the rise in CO 2 can impact physiology and biomineralization in marine calcifiers such as eastern oysters, threatening their survival and potentially leading to profound ecological and economic impacts in estuarine ecosystems.
Ferrimagnetic Resonance of Single-Crystal Barium Ferrite in the Millimeter Wave Region (1961)

First Page