gebhart/patrepeval huggingface dataset:
Determination of the strong coupling constant from transverse energy-energy correlations in multijet events at $$ \sqrt{s} $$ = 13 TeV with the ATLAS detector (2023)

A bstract Measurements of transverse energy-energy correlations and their associated azimuthal asymmetries in multijet events are presented. The analysis is performed using a data sample corresponding to 139 fb − 1 of proton-proton collisions at a centre-of-mass energy of $$ \sqrt{s} $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msqrt> <mml:mi>s</mml:mi> </mml:msqrt> </mml:math> = 13 TeV, collected with the ATLAS detector at the Large Hadron Collider. The measurements are presented in bins of the scalar sum of the transverse momenta of the two leading jets and unfolded to particle level. They are then compared to next-to-next-to-leading-order perturbative QCD calculations for the first time, which feature a significant reduction in the theoretical uncertainties estimated using variations of the renormalisation and factorisation scales. The agreement between data and theory is good, thus providing a precision test of QCD at large momentum transfers Q . The strong coupling constant α s is extracted as a function of Q , showing a good agreement with the renormalisation group equation and with previous analyses. A simultaneous fit to all transverse energy-energy correlation distributions across different kinematic regions yields a value of $$ {\alpha}_{\textrm{s}}\left({m}_Z\right)=0.1175\pm 0.0006{\left(\exp .\right)}_{-0.0017}^{+0.0034}\left(\textrm{theo}.\right) $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>α</mml:mi> <mml:mi>s</mml:mi> </mml:msub> <mml:mfenced> <mml:msub> <mml:mi>m</mml:mi> <mml:mi>Z</mml:mi> </mml:msub> </mml:mfenced> <mml:mo>=</mml:mo> <mml:mn>0.1175</mml:mn> <mml:mo>±</mml:mo> <mml:mn>0.0006</mml:mn> <mml:msubsup> <mml:mfenced> <mml:mrow> <mml:mo>exp</mml:mo> <mml:mo>.</mml:mo> </mml:mrow> </mml:mfenced> <mml:mrow> <mml:mo>−</mml:mo> <mml:mn>0.0017</mml:mn> </mml:mrow> <mml:mrow> <mml:mo>+</mml:mo> <mml:mn>0.0034</mml:mn> </mml:mrow> </mml:msubsup> <mml:mfenced> <mml:mrow> <mml:mtext>theo</mml:mtext> <mml:mo>.</mml:mo> </mml:mrow> </mml:mfenced> </mml:math> , while the global fit to the asymmetry distributions yields $$ {\alpha}_{\textrm{s}}\left({m}_Z\right)=0.1185\pm 0.0009{\left(\exp .\right)}_{-0.0012}^{+0.0025}\left(\textrm{theo}.\right) $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msub> <mml:mi>α</mml:mi> <mml:mi>s</mml:mi> </mml:msub> <mml:mfenced> <mml:msub> <mml:mi>m</mml:mi> <mml:mi>Z</mml:mi> </mml:msub> </mml:mfenced> <mml:mo>=</mml:mo> <mml:mn>0.1185</mml:mn> <mml:mo>±</mml:mo> <mml:mn>0.0009</mml:mn> <mml:msubsup> <mml:mfenced> <mml:mrow> <mml:mo>exp</mml:mo> <mml:mo>.</mml:mo> </mml:mrow> </mml:mfenced> <mml:mrow> <mml:mo>−</mml:mo> <mml:mn>0.0012</mml:mn> </mml:mrow> <mml:mrow> <mml:mo>+</mml:mo> <mml:mn>0.0025</mml:mn> </mml:mrow> </mml:msubsup> <mml:mfenced> <mml:mrow> <mml:mtext>theo</mml:mtext> <mml:mo>.</mml:mo> </mml:mrow> </mml:mfenced> </mml:math> .
Hazards of Disposable Rebreathing Circuits (1976)

COTTRELL, JAMES E. MD*; BERNHARD, WILLIAM MD†; TURNDORF, HERMAN MD‡Editor(s): MUNSON, EDWIN S.; STOELTING, ROBERT K. Author Information
DPI: The Data Processing Interface for Modern Networks (2019)

As data processing evolves towards large scale, distributed platforms, the network will necessarily play a substantial role in achieving efficiency and performance. Increasingly, switches, network cards, and protocols are becoming more flexible while programmability at all levels (aka, software defined networks) opens up many possibilities to tailor the network to data processing applications and to push processing down to the network elements.

In this paper, we propose DPI, an interface providing a set of simple yet powerful abstractions flexible enough to exploit features of modern networks (e.g., RDMA or in-network processing) suitable for data processing. Mirroring the concept behind the Message Passing Interface (MPI) used extensively in high-performance computing, DPI is an interface definition rather than an implementation so as to be able to bridge different networking technologies and to evolve with them. In the paper we motivate and discuss key primitives of the interface and present a number of use cases that show the potential of DPI for data-intensive applications, such as analytic engines and distributed database systems.
Bio-Based Flame-Retardant Coatings Based on the Synergistic Combination of Tannic Acid and Phytic Acid for Nylon–Cotton Blends (2021)

Natural and synthetic polymeric fibers are used extensively in making fabrics for a variety of civilian and military applications. Due to the durability and comfort, nyco, a 50-50% blend of nylon 66 and cotton, is used as the material of choice in many applications including military uniforms. This fabric is flammable due to the presence of cotton and nylon but has good mechanical properties and is comfortable to wear. Here, we report a novel surface functionalization method that utilizes a synergistic combination of bio-based materials, tannic acid (TA) and phytic acid (PA), to impart flame-retardant (FR) properties to the nyco fabric. TA and PA were sequentially attached to nylon and cotton fibers through hydrogen bonding interactions and phosphorylation, respectively. The surface functionalization of the treated fabrics was confirmed using Fourier-transform infrared spectroscopy. Thermogravimetric analysis, microscale combustion calorimetry, cone calorimetry, and vertical flame testing were employed to study the effect of the functionalization on the thermal stability and flammability of the nyco fabric. Though reasonable durable functionalization is observed from elemental analysis, it is not enough to impart wash-durable FR treatment. These results indicate that flame retardancy is enabled through the enhanced char formation provided by the combination of TA and PA. The TA-PA system applied to nyco shows great promise as a bio-based FR system. This study for the first time also provides evidence for the selectivity of TA in imparting FR characteristics for nylon and PA in imparting FR properties for cotton. The combination of TA and PA provides promising FR characteristics to nyco.
16.1 A nanogap transducer array on 32nm CMOS for electrochemical DNA sequencing (2016)

In this paper, we have demonstrated a highly scalable all-electronic approach towards DNA sequencing using CMOS readout electronics coupled with post-processed nanogap transducers. While this test chip demonstrated a small array of 8,192 pixels, a 25mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> chip could theoretically contain over 12 million pixels including I/O pads. Through careful architectural design choices and selection of a novel transduction scheme, we demonstrate that biosensing, such as DNA sequencing, can be performed on advanced CMOS process nodes.
Non-invasive authentication of mail packages using nuclear quadrupole resonance spectroscopy (2023)

Abstract The international postal network is one of the most widely used methods for correspondence throughout the world. Most postal traffic across the globe consists of legitimate interpersonal, business-consumer, and business-business communications. However, the global postal system is also utilized for criminal activity. In particular, it is often utilized to ship and distribute contraband, including illegal psychoactive drugs such as fentanyl and heroin, to consumers. Existing technological solutions are capable of identifying synthetic opioids and other illegal drugs within packages, but are accompanied by several disadvantages that make them unsuitable for large-scale authentication of international mail traffic. This paper presents a novel method for non-invasive authentication of mail packages that overcomes these challenges. The approach uses nuclear quadrupole resonance (NQR) spectroscopy to detect and quantify the presence of known active pharmaceutical ingredients (APIs) within the package. It has been experimentally demonstrated using a bench top prototype. Test results from a variety of package types demonstrate the effectiveness of the proposed authentication approach.
Texture Evaluation of Carpets Using Image Analysis (1991)

This paper explores in detail new image enhancement techniques for assessing tuft geometry and concomitant appearance changes in new and worn carpets. Using im proved algorithms and more advanced tuft geometry, saxony tufted carpets of nylon and polyester BCF yams are capable of being extensively and reliably characterized as to texture and changes in appearance with laboratory or floor wear. While still using a relatively low resolution grey level imaging system, the newly developed al gorithms demonstrate how tuft size distribution, number of tufts, evenness of tuft spatial distribution, and aspect ratio (shape factor) of tufts can be objectively measured. Statistical analysis confirms that customary wear levels, and their visual appearance change in carpet, can be separated and correctly grouped by these new techniques. Some limitations of these and other texture-sensitive image analysis techniques are also discussed.
Anatomical and Morphological Evaluation of Pacemaker Lead Compression (1993)

In recent years, pacemaker lead failure due to compressive damage has been reported with increasing frequency. To document the mechanism of this failure, we evaluated explanted mechanically damaged leads with electrical testing, optical microscopy, and in some cases, scanning electron microscopy (SEM). In addition, we performed an autopsy study to measure the compressive loads on catheters placed percutaneously through the costoclavicular angle, as well as by cephalic cutdown. Of the 49 explanted compression damaged leads with enough clinical data for analysis, all had been placed by percutaneous subclavian puncture. Our autopsy data confirmed the significant increase in pressures generated in the costoclavicular angle for medial percutaneous subclavian catheterization (126 +/- 26 mmHg) compared to a more lateral percutaneous subclavian puncture (63 +/- 15 mmHg) or a cephalic cutdown (38 +/- 13 mmHg) (P < 0.01). In vivo coil compression testing documented loads up to 100 pounds per linear inch of coil and a compressive morphology by SEM identical to that seen in the clinical explants. Pacemaker leads appear to be susceptible to compression damage when placed by subclavian venipuncture. When possible, leads should be placed such that they avoid the tight costoclavicular angle.
A Dynamic Resource Management and Scheduling Environment for Embedded Multimedia and Communications Platforms (2010)

We present a framework, OpenCLosE, for dynamic resource management and scheduling of applications written in open compute language (OpenCL) for heterogeneous multimedia and graphics platforms, such as those found in multimedia smartphones and automotive infotainment clusters. We describe the design of a resource manager and master scheduler for the OpenCLosE environment, that allows efficient realization of multiple applications within a multitasked platform.
Microstructural study of an oscillatory formation reaction in nanostructured reactive multilayer foils (2005)

We report evidence of an oscillatory formation reaction in nanostructured Zr∕Al∕(CuNi) reactive multilayer foils. The oscillations create periodic ripples on the surface of the foil as well as periodic variations in the length scale of the microstructure of the reacted foil. We describe the nature of the resulting microstructure, and relate this to superadiabatic temperature oscillations at the reaction front. We also examine the effect of ambient temperature on the magnitude and period of the oscillations, and compare the results to numerical predictions and to experimental data for other reactive systems.
Abstract 1948: Pvt1-encoded microRNA miR-1204 in tumorigenesis of human ovarian and breast cancer (2010)

Abstract Amplification at chromosome 8q24 is one of the most frequent genomic abnormalities in human cancers and is associated with reduced survival duration in ovarian and breast cancers. Recently, microRNAs (miRNAs) at 8q24 have been identified in the PVT1 locus. Herein, we explored the biological functions of one miRNA, miR-1204, residing within the exon1B of PVT1. Mature hsa-mir-1204 is over-expressed in PVT1 amplified ovarian and breast cancer cell lines (HEY, OVCAR8, SUM-159PT and MDA-MB231). In vitro treatment with antagomir against hsa-mir-1204 inhibited cell proliferation and induced apoptosis in the four PVT1 amplified ovarian and breast cancer lines. Conversely, over-expression of miR-1204 promoted cell growth in PVT1 non-amplified ovarian and breast cancer lines (OV90 and MCF10A) and cooperated with c-Myc to potentiate Rat1A cell colony growth in soft agar assays. Since an inverse expression pattern is often present between miRNA and its target genes, we used computational approaches (miRanda, TargetScan, Pita) to identify distinct miR-1204 candidate target genes from two independent expression microarray datasets, one with significantly down-regulated genes by PVT1 copy number gain in 147 breast tumors and the other involving genes significantly repressed by miR-1204 overexpression and derepressed by silencing of miR-1204 in ovarian and breast cancer cells. Thirty putative target genes of miR-1204 were empirically verified by Q-RT-PCR method, and this group of genes was enriched with genes regulating cell death, cell growth and proliferation, cell cycle, cellular assembly and organization. Combined, these data suggest that human miR-1204 contributes to ovarian and breast tumor proliferation and survival and down-regulates distinct targets including multiple tumor suppressor genes and serves as a potential therapeutic target against tumors with 8q24 amplification. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010;70(8 Suppl):Abstract nr 1948.
Standardized Method for Intra-Cisterna Magna Delivery Under Fluoroscopic Guidance in Nonhuman Primates (2018)

Intrathecal delivery of adeno-associated virus vectors and other therapeutics are currently being evaluated for the treatment of central nervous system sequelae of lysosomal storage diseases, motor neuron diseases, and neurodegenerative diseases. As products transition from preclinical to clinical studies, a standardized and clinically relevant method of intrathecal delivery is increasingly germane. Here, we describe a method of intrathecal delivery via suboccipital puncture into the cisterna magna under fluoroscopic guidance in nonhuman primates. This procedure is suitable for use in good laboratory practice compliant studies, has an excellent safety profile, and is highly similar to the procedure currently being explored for use in humans.
A simple and rapid formation of wet chemical etched silicon nanowire films at the air–water interface (2011)

A spontaneous assembly route to form a thin film of nanowires (NWs) was demonstrated and its feasibility was confirmed through the fabrication of a high-performance multi-Si NW field effect transistor (FET) using this route. Governed by the three mechanisms of spreading, trapping, and two-dimensional packing, the route was optimized for the concentration of Si NWs and the initial volume ratio of aqueous hydrochloride solution to isopropyl alcohol. The successfully formed Si NW thin-film was transferred on a flat polydimethylsiloxane (PDMS) mold and regulated using a repeatable conformal contact method with a new flat PDMS to prepare it for decal printing on an organic dielectric layer. Finally, after depositing the source and drain electrodes on the printed active layer, a high-performance 23-bridged Si NW FET exhibiting a μeff of 51.4 cm2 V−1s−1, an on/off drain current ratio of 105, and a Vth of −2.7 V was obtained.
Design of sugar-based surface active agents for emulsion polymerization in supercritical carbon dioxide (2012)

The use of aqueous dispersed media, such as emulsions, has many advantages over solution processes for chemical transformations and polymerization reactions, i.e. limited environmental impact, ease of products recovery and increased reaction rate. Emulsions are usually implemented from a water/organic solvent mixture in the presence of a surfactant. However, supercritical carbon dioxide (scCO2) (Pc =74 bars; Tc = 31°C) constitutes an interesting alternative to the traditional organic solvents in these heterogeneous systems because it is inexpensive, non-toxic, non-inflammable and environmentally friendlier. In this context, we developed a novel class of surfactants for the stabilization of H2O/scCO2 emulsions, i.e. fluorinated modified carbohydrates. The hydrophilic head of the surfactant consists in a sugar moiety whereas a fluorinated tail is specifically located in the scCO2 phase. The strategies for the synthesis of these carbohydrates esters rely on selective lipase-catalyzed modifications of sugars and on the versatile thiol-Michael addition reaction. The ability of these molecules to decrease the H2O/scCO2 interfacial tension and to stabilize such emulsions will be presented. Finally, high internal phase scCO2-in-water emulsion (HIPE) were prepared with these new surfactants and used as template for the acrylamide polymerization. The monomer is polymerized in the continuous aqueous phase before removing the CO2 droplets (at least 70 % of the total volume). The resulting permeable porous polymers, called polyHIPEs, exhibit highly interconnected voids (cfr SEM picture) and should be valuable in many applications including support for catalyst, filtration process, immobilization of proteins, etc.
julia v0.5.0-rc3 (2016)

We have been fixing 0.5-critical bugs since the last release candidate, and are now releasing 0.5.0-rc3. Links to binary installers will be sent to the julia-users and julia-news mailing lists. We have branched for release-0.5 - new development will take place on master which is now 0.6-dev, and bug fixes will be backported to the release-0.5 branch according to the steps described at https://github.com/JuliaLang/julia/issues/17418#issue-165613676. A prepared tarball (the output of make light-source-dist) is attached below in julia-0.5.0-rc3.tar.gz, use this if a source tarball is desired, as it contains a small amount of preparation that a simple archive of the git repository does not. For source builds in restricted environments (e.g. no network access) use the output of make full-source-dist attached below in julia-0.5.0-rc3-full.tar.gz as it already contains all dependencies pre-downloaded and ready for compilation.
A biodegradable polyurethane‐ascorbic acid scaffold for bone tissue engineering (2003)

A novel, nontoxic, biodegradable, sponge-like polyurethane scaffold was synthesized from lysine-di-isocyanate (LDI) and glycerol. Ascorbic acid (AA) was copolymerized with LDI-glycerol. Our hypothesis was that the AA-containing polymer foam would enhance the biological activity of the osteoblastic precursor cell (OPCs). The LDI-glycerol-AA matrix degraded in aqueous solution to the nontoxic products of lysine, glycerol, and AA. The degradation products did not significantly affect the solution pH. The physical properties of the polymer network supported the cell growth in vitro. Mouse OPCs attached to the polymer matrix and remained viable. OPCs produced multilayered confluent cultures, a characteristic typical of bone cells. Furthermore, AA release stimulated cell proliferation, type I collagen, and alkaline phosphatase synthesis. Cells grown on the LDI-glycerol-AA matrix also showed an enhancement of mRNA expression for pro-alpha1 (I) collagen and transforming growth factor-alpha1 after 1 week. Data were tested for significance with an analysis of variance model and multiple comparison test (Fisher's Protected Least Significant Difference) at p < or = 0.05. The observations suggest that AA-containing polyurethane may be useful in bone tissue engineering applications.
Fluorescence excitation and detection on a chip using nanophotonic waveguides(Conference Presentation) (2016)

Often, in bio-sensing applications rely on fluorescence as the transduction mechanism. The emission from the fluorescently labeled molecules is detected and quantified to obtain the concentration. Most current techniques, such as ELISA, FISH, next generation DNA sequencing and others need one or several washing steps to remove the unreacted fluorescent molecules to reduce the background noise. To address that problem, we propose an integrated nano-photonic solution for on-chip fluorescence detection. The proposed platform is tailored for bio-sensing applications and has the potential to analyze bio-molecular interactions down to the single molecule level. The technology is based on near-field excitation and collection using PECVD Silicon Nitride (SiN) nano-photonic rib waveguides. SiN provides the combination of high-index-contrast and compatibility with CMOS processing technology, and unlike silicon, Silicon Nitride does not absorb in the visible wavelength window. The evanescent tail of the used SiN waveguide mode extends from 80 nm to 200 nm above the waveguide surface depending on the waveguide geometry, cladding material and excitation wavelength. Hereby, the evanescent field of the waveguide mode excites a very thin layer of molecules near to the surface. The subsequent emission from the excited fluorophore is collected in the near field by coupling to another waveguide. The coupling strength mainly depends on the distance between the waveguide and fluorophore. This way, both the excitation and collection efficiency have an exponential dependency on the distance between the molecule and waveguide surface. Therefore, exciting and collecting fluorescence using photonic waveguides improves the separation between the surface bound fluorescence signal from the bulk background noise, paving the way for wash free bio-sensing. Wash-free assays allow to examine the bio-molecular interactions in real time and simplify the sample/liquid handling system. Next to bulk fluorescence, autofluorescence generated in the SiN waveguide is another large contributor to noise. In the proposed design, the two separate single mode waveguides we use to excite fluorophores and collect the emission, are placed orthogonally in a cross configuration. The orthogonal placement of two Transverse Electric (TE) mode waveguides makes sure that the auto-fluorescence generated in the excitation waveguide is not coupled to the emission waveguide. As a result, we observe an improved signal-to-noise-ratio (SNR) which is a very critical parameter towards single molecule detection. In this talk, I will talk about the design, fabrication and characterization of the proposed cross-configured waveguide based fluorescence detection platform. Experimental results to quantify the excitation efficiency, collection efficiency and SNR will be discussed. A comparison will be shown between the Finite Difference Time Domain (FDTD) simulation and experimental results.
Hepcidin, a candidate modifier of the hemochromatosis phenotype in mice (2003)

Hereditary hemochromatosis (HH) type I is a disorder of iron metabolism caused by a mutation in the HFE gene. Whereas the prevalence of the mutation is very high, its penetrance seems very low. The goal of our study was to determine whether hepcidin, a recently identified iron-regulatory peptide, could be a genetic modifier contributing to the HH phenotype. In mice, deficiency of either HFE (Hfe(-/-)) or hepcidin (Usf2(-/-)) is associated with the same pattern of iron overload observed in patients with HH. We intercrossed Hfe(-/-) and Usf2(+/-) mice and asked whether hepcidin deficiency increased the iron burden in Hfe(-/-) mice. Our results showed that, indeed, liver iron accumulation was greater in the Hfe(-/-)Usf2(+/-) mice than in mice lacking Hfe alone. This result, in agreement with recent findings in humans, provides a genetic explanation for some variability of the HH phenotype.