gebhart/patrepeval huggingface dataset:
Optomechanical nanoantenna: far-field control of near-field through mechanical reconfiguration (2015)

We have introduce optomechanical nanoantennae, which showed dramatic changes in scattering properties by minuscule changes in geometry. These structures are very compact, with a volume 500 times smaller than free space optical wavelength volume. Through these optical elements, far-field can directly control the near-field of antenna by mechanical reconfiguration. Here we present the functionality of the optomechanical nanoantenna and challenges in fabricating and measuring these devices.
Accurate numerical integration of singular boundary element kernels over boundaries with curvature (1985)

Abstract Use of the Green function, for the solution of boundary‐value problems, frequently results in singular integral equations. Algorithms are presented for the accurate and efficient treatment of singular kernels frequently encountered in the boundary element method (BEM). They are based upon the use of appropriately weighted Gaussian quadrature formulae, together with numerical geometrical transformations of the region of integration. The use of high‐order subdomain expansion functions, for interpolation over nonplanar elements, allows boundary curvature to be accommodated. In particular, the handling of Green functions with logarithmic and r −1 behaviour are detailed. Volume integrals, with r −2 singularity, are outlined. Operations are performed on a simplex, thus resulting in generality and ease of automation. This scheme has been incorporated into boundary element method software and successfully applied to a variety of problems.
<title>Induction of endogenic porphyrin production in bacteria and subsequent photoinactivation by various light sources</title> (1997)

(delta) -aminolevulinic acid (ALA) induces the production of very high amounts of porphyrins in Gram-positive and Gram- negative bacteria. Accumulation of the porphyrins in the bacterial cell is a consequence of the high porphyrin production but most of the porphyrins are excreted from the cells into the medium. By fluorescence, measurements of the endogenic and of the exogenic content of the produced porphyrins can be determined. Bacteria loaded by their own accumulated porphyrins can undergo photoinactivation by various light sources. Killing of S. aureus cells by its endogenic porphyrins can be achieved by illumination with intense blue lights or by HeNe laser. E. coli cells loaded with endogenic porphyrins can be photoinactivated by intense blue and red light.
Piracy Protection for Streaming Content in Home Networks (2011)

In this paper we study content protection techniques to defend against piracy for streaming content in home networks where multiple digital devices are connected into a peer-based cluster and seamlessly work together. We are particularly interested in the anonymous re-broadcasting attack where pirates re-distribute the per-content encrypting key or the decrypted plain content. In literature, to defend against an anonymous attack, content is usually built with different variations. For example, content is divided into multiple segments, each segment comes with multiple variations (e.g., watermarks), and each variation is differently encrypted. Each device only has the key to decrypt and play back one variation per segment through the content. The re-distributed keys can be linked back and used to identify the original devices (terms as traitors) who were given those keys and involved in the piracy. This technology works well for prerecorded content scenarios in which a trusted party outside the device pool can deliberately author the content with multiple variations. However it cannot be applied to a peer-based home network when the streaming content is brought into the home network via a peer device who is not a special trust party and who is not allowed to know the secret keys of other peer devices. On the other hand, the trend of the consumer appetite for digital content is increasingly switching from physical media to streaming and internet consumption. In this paper we have designed the first content protection system that allows a recording device inside the home network to bring the streaming content into the home network in a secure way that devices and only devices in the same home network can playback the recording. More importantly, the recorded content without variations can still be used to obtain forensic information, when anonymous piracy attacks occurs, to identify the source devices that participated in the piracy attack. The identified traitorous devices can be revoked for future content access. The technology described in this paper is used to enable the secure sharing of premium quality High Definition content across a consumer’s all audio-video devices at its home networks.
Towards an understanding of emergence in systems-of-systems (2015)

Emergence is a systemic phenomenon in an System-of-Systems (SoS) that cannot be reduced to the behavior of the isolated parts of a system. It is the objective of this paper to contribute to the understanding of emergent phenomena in SoSs. After a short look at the literature on emergence in the domains of philosophy and computer science, this paper continues with an elaboration on multi-level nearly-decomposable systems, gives a tentative definition of emergence and discusses how emergent behavior manifests itself in an SoS.
Plasma proteome profiles treatment efficacy of incretin dual agonism in diet‐induced obese female and male mice (2020)

We herein show that a recently developed unimolecular GLP-1/GIP co-agonist is more efficient in improving metabolic disease than either mono-agonist in both sexes. PPP led to the identification of a sex-independent protein panel with the potential to monitor non-invasively the treatment efficacies on metabolic function of this clinically advancing GLP-1/GIP co-agonist.
Three-Layered Polyelectrolyte Structures as Inkjet Receptive Coatings: Part 1. Interaction with Dye-based Ink (2015)

The effect of the structure of three-layer polyelectrolyte coatings on the interaction with a water-based inkjet ink comprising dye colorants was determined. Various combinations of anionic&#x2010;cationic polyelectrolyte structures were prepared on base paper having different hydrophobicity obtained by varying dosages of an alkyl succinic anhydride (ASA) internal sizing agent. Thin coating layers of anionic NaCMC and/or cationic PDADMAC were alternately wet-on-wet spray-coated onto the substrates. It was found that the level of internal sizing affected the spreading and absorption of dye-based inkjet ink, but that the behavior was strongly dependent on the chemistry and structural composition of the deposited polyelectrolyte layer. Polyelectrolyte surface treatment had an effect on the print quality and, e.g., the print density could be improved with cationic surface treatment but also with increasing level of internal sizing. A significant difference in the water fastness of the printed samples was seen, which could be ascribed to the influence of complexes formed between anionic and cationic polyelectrolytes and to their interactions with ink colorants.
CD4+and CD8+T Cells Mediate Adoptive Immunity to Aerosol Infection ofMycobacterium bovisBacillus Calmette‐Guérin (2000)

An adoptive-transfer model using recombinase activation gene-deficient (RAG-1-/-) mice was developed to evaluate CD4+ and CD8+ T cell responses to infection with Mycobacterium bovis bacillus Calmette-Guérin (BCG). After receiving immune, unfractionated T cells or T cell subsets isolated by fluorescence-activated cell sorter, the RAG-1-/- mice were exposed to aerosol BCG, and the bacteria load in the infected organs was examined 4 weeks later. Adoptive immunity was expressed more effectively in the spleens than in the lungs. Although CD4+ or unfractionated T cells protected both lungs and spleens, CD8+ T cells conferred significant protection only in the spleens and not in the lungs. The results confirm that in addition to CD4+, CD8+ T cells also play a role in the prevention of bacterial dissemination. This transfer model may be useful for dissecting T cell responses to mycobacterial infection.
3T3 cell motility in the temperature range 33°C to 39°C (1987)

The phenomena of mammalian cell motility in tissue culture is an integrated function of many cellular components. As such, cell motility is very sensitive to external stimuli and perturbation. In this article we report the effect of temperature in the range 33 degrees C to 39 degrees C on cell motility. For this 3T3 cells were plated in plastic tissue culture flasks. A large number of individual cells (60 per experiment) were tracked as a function of time by means of an automated device, the Cell Analyzer. The data show a peak in the average cell speed in the range 36.5 degrees C to 38.5 degrees C, falling off sharply at lower and higher temperatures. The average rate of cell motility closely correlates to the average cell proliferation rate in the range 33 degrees C to 39 degrees C.
Fulvoferruginin, a Carotane Antibiotic from Marasmius fulvoferrugineus Gilliam [1] (1990)

Abstract The structure of fulvoferruginin (1), a carotane derivative from cultures of Marasmius fulvoferrugineus, has been established by spectroscopic investigations and an X -ray structure analysis. 1 exhibits antibacterial, antifungal. and cytotoxic activities.
Durable and controlled depletion of neutrophils in mice (2020)

Neutrophils are an essential part of the innate immune system. To study their importance, experimental studies often aim to deplete these cells, generally by injecting anti-Ly6G or anti-Gr1 antibodies. However, these approaches are only partially effective, transient or lack specificity. Here we report that neutrophils remaining after anti-Ly6G treatment are newly derived from the bone marrow, instead of depletion escapees. Mechanistically, newly generated, circulating neutrophils have lower Ly6G membrane expression, and consequently reduced targets for anti-Ly6G-mediated depletion. To overcome this limitation, we develop a double antibody-based depletion strategy that enhances neutrophil elimination by anti-Ly6G treatment. This approach achieves specific, durable and controlled reduction of neutrophils in vivo, and may be suitable for studying neutrophil function in experimental models.
Reduced Graphene Oxide/Carbon Nanotube/Gold Nanoparticles Nanocomposite Functionalized Screen‐Printed Electrode for Sensitive Electrochemical Detection of Endocrine Disruptor Bisphenol A (2015)

Abstract We fabricated a highly sensitive electrochemical sensor for the determination of bisphenol A (BPA) in aqueous solution by using reduced graphene oxide (RGO), carbon nanotubes (CNT), and gold nanoparticles (AuNPs)‐modified screen‐printed electrode (SPE). GO/CNT nanocomposite was directly reduced to RGO/CNT on SPE at room temperature. AuNPs were then electrochemically deposited in situ on RGO/CNT‐modified SPE. Under optimized conditions, differential pulse voltammetry (DPV) produced linear current responses for BPA concentrations of 1.45 to 20 and 20 to 1,490 nM, with a calculated detection limit of an ultralow 800 pM. The sensor response was unaffected by the presence of interferents such as phenol, p ‐nitrophenol, pyrocatechol, 2,4‐dinitrophenol, and hydroquinone.
Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause deadly disease (2023)

Pan-betacoronavirus neutralizing antibodies may hold the key to developing broadly protective vaccines against novel pandemic coronaviruses and to more effectively respond to SARS-CoV-2 variants. The emergence of Omicron and subvariants of SARS-CoV-2 illustrates the limitations of solely targeting the receptor-binding domain (RBD) of the spike (S) protein. Here, we isolated a large panel of broadly neutralizing antibodies (bnAbs) from SARS-CoV-2 recovered-vaccinated donors, which targets a conserved S2 region in the betacoronavirus spike fusion machinery. Select bnAbs showed broad in vivo protection against all three deadly betacoronaviruses, SARS-CoV-1, SARS-CoV-2, and MERS-CoV, which have spilled over into humans in the past two decades. Structural studies of these bnAbs delineated the molecular basis for their broad reactivity and revealed common antibody features targetable by broad vaccination strategies. These bnAbs provide new insights and opportunities for antibody-based interventions and for developing pan-betacoronavirus vaccines.
High Hamstring Tendinopathy in Runners: Meeting the Challenges of Diagnosis, Treatment, and Rehabilitation (2005)

In BriefIn BriefHigh hamstring tendinopathy is an uncommon overuse injury seen in running athletes. Patients typically report deep buttock or thigh pain. A detailed physical examination and, occasionally, imaging studies are necessary to confirm the diagnosis. Rehabilitation involves soft-tissue mobilization, frequent stretching, and progressive eccentric hamstring strengthening and core stabilization exercises. In recalcitrant cases, an ultrasound-guided corticosteroid injection into the tendon sheath can be helpful, and, occasionally, surgery may be necessary to release the scar tissue around the proximal hamstring muscles and the sciatic nerve.
Mixed Higher‐Order Cyanocuprate‐Induced Epoxide Openings: 1‐Benzyloxy‐4‐Penten‐2‐ol (2003)

Abstract Mixed higher‐order cyanocuprate‐induced epoxide openings: 1‐benzyloxy‐4‐penten‐2‐ol reactant: (±)‐benzyl 2,3‐epoxypropyl ether (7.34 g, 44.7 mmol, 83%) product: (R)‐1‐Benzyloxy‐4‐penten‐2‐ol
Human Onchocerciasis: Modelling the Potential Long-term Consequences of a Vaccination Programme (2015)

An onchocerciasis prophylactic vaccine would reduce the onchocerciasis disease burden in populations where ivermectin cannot be administered safely. Moreover, a vaccine could substantially decrease the chance of re-emergence of Onchocerca volvulus infection in areas where it is deemed that MDA with ivermectin can be stopped. Therefore, a vaccine would protect the substantial investments made by present and past onchocerciasis control programmes, decreasing the chance of disease recrudescence and offering an important additional tool to mitigate the potentially devastating impact of emerging ivermectin resistance.
Redox shuttles having an aromatic ring fused to a 1,1,4,4-tetrasubstituted cyclohexane ring (2023)

An electrolyte includes an alkali metal salt; an aprotic solvent; and a redox shuttle additive including an aromatic compound having at least one aromatic ring fused with at least one non-aromatic ring, the aromatic ring having two or more oxygen or phosphorus-containing substituents.
Severe Combined Immunodeficiency Mice Engrafted With Human T Cells, B Cells, and Myeloid Cells After Transplantation With Human Fetal Bone Marrow or Liver Cells and Implanted With Human Fetal Thymus: A Model for Studying Human Gene Therapy (1997)

To develop an in vivo model wherein human hematopoiesis occurs, we transplanted severe combined immunodeficiency (SCID) mice with either human fetal bone marrow (HFBM) or human fetal liver (HFL). After transplantation of SCID mice with cultured HFBM (BM-SCID-hu mice) or HFL cells (Liv-SCID-hu mice), significant engraftment of the mouse bone marrow (BM) and population of the peripheral blood with human leukocytes was detected. Human colony-forming unit-granulocyte macrophage and burst forming unit-erythroid were detected in the BM of the BM-SCID-hu and Liv-SCID-hu mice up to 8 months after transplantation. When the HFBM or HFL cells were transduced with a retroviral vector before transplantation, integrated retroviral sequences were detected in human precursor cells present in the SCID mouse BM and in leukocytes circulating in the peripheral blood (PB) up to 7 months after transplantation. The PB of the BM-SCID-hu mice also became populated with human T cells after implantation with human thymic tissue, which provided a human microenvironment wherein human pre-T cells from the BM could mature. When the HFBM was retrovirally transduced before transplantation, integrated retrovirus was detected in sorted CD4+CD8+ double positive and CD4+ single positive cells from the thymic implant and CD4+ cells from the PB. Taken together, these data indicated that the BM of our BM-SCID-hu and Liv-SCID-hu mice became engrafted with retrovirally transduced human hematopoietic precursors that undergo the normal human hematopoietic program and populate the mouse PB with human cells containing integrated retroviral sequences. In addition to being a model for studying in vivo human hematopoiesis, these mice should also prove to be a useful model for investigating in vivo gene therapy using human stem/precursor cells.
Information-flow models for shared memory with an application to the powerPC architecture (2003)

This paper introduces a generic framework for defining instructions, programs, and the semantics of their instantiation by operations in a multiprocessor environment. The framework captures information flow between operations in a multiprocessor program by means of a reads-from mapping from read operations to write operations. Two fundamental relations are defined on the operations: a program order between operations which instantiate the program of some processor and view orders which are specific to each shared memory model. An operation cannot read from the "hidden" pastor from the future; the future and the past causality can be examined either relative to the program order or relative to the view orders. A shared memory model specifies, for a given program, the permissible transformation of resource states. The memory model should reflect the programmer's view by citing the guaranteed behavior of the multiprocessor in the interface visible to the programmer. The model should retrain from dictating the design practices that should be followed by the implementation. Our framework allows an architect to reveal the programming view induced by a shared-memory architecture; it serves programmers exploring the limits of the programming interface and guides architecture-level verification. The framework is applicable for complex, commercial architectures as it can capture subtle programming-interface details, exposing the underlying aggressive microarchitecture mechanisms. As an illustration, we define the shared memory model supported by the PowerPC architecture, within our framework.
How Subtle Changes Can Make a Difference: Reproducibility in Complex Supramolecular Systems (2022)

Abstract The desire to construct complex molecular systems is driven by the need for technological (r)evolution and our intrinsic curiosity to comprehend the origin of life. Supramolecular chemists tackle this challenge by combining covalent and noncovalent reactions leading to multicomponent systems with emerging complexity. However, this synthetic strategy often coincides with difficult preparation protocols and a narrow window of suitable conditions. Here, we report on unsuspected observations of our group that highlight the impact of subtle “irregularities” on supramolecular systems. Based on the effects of pathway complexity, minute amounts of water in organic solvents or small impurities in the supramolecular building block, we discuss potential pitfalls in the study of complex systems. This article is intended to draw attention to often overlooked details and to initiate an open discussion on the importance of reporting experimental details to increase reproducibility in supramolecular chemistry.
Flowspec Indirection-id Redirect (2020)

This document defines a new extended community known as FlowSpec
Redirect to indirection-id Extended Community. This extended
community triggers advanced redirection capabilities to flowspec
clients. When activated, this flowspec extended community is used by a
flowspec client to retrieve the corresponding next-hop and encoding
information within a localised indirection-id mapping table. The
functionality detailed in this document allows a network controller to
decouple the BGP flowspec redirection instruction from the operation
of the available paths.
Evaluating Different Implementations of Online Junction Temperature Sensing for Switching Power Semiconductors (2016)

Switching power semiconductor online junction temperature T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">j</sub> sensing is essential for device switching performance evaluation, device switching control, and device lifetime optimization. The contribution of this paper is a detailed evaluation of the implementation issues (including circuit invasiveness, hardware integration, signal processing, and so forth) of different online Ti sensing methods. This paper includes T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">j</sub> sensing methods based on device power dissipation, T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">j</sub> sensing methods based on the “sensoron-die technology,” T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">j</sub> sensing methods based on device on-state analysis, and T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">j</sub> sensing methods based on device switching transients. Advantages and limits of these methods are also provided.
Spectroscopic study of film formation from polystyrene latex/TiO2 nanocomposites prepared by dip‐coating method (2013)

In this study, we investigated the influence of TiO 2 content and thickness of polystyrene (PS) template on film‐formation behavior of PS/TiO 2 composites using fluorescence and ultraviolet–visible techniques in conjunction with scanning electron microscopy. Films were prepared by coating PS templates with various layers of TiO 2 using dip‐coating method. The results showed that PS latexes present complete film formation on top surface of composites. After extraction of PS, a well‐defined interconnected porosity were obtained for thin films when TiO 2 content was increased, whereas thick samples did not present any interconnected porous structures above a certain TiO 2 layer. POLYM. ENG. SCI., 54:288–302, 2014. © 2013 Society of Plastics Engineers