gebhart/patrepeval huggingface dataset:
Premières récoltes françaises de Peziza acroornata (Ascomycota, Pezizales) (2009)

The authors present in detail the first French collections of a very rare cup-fungus, Peziza acroornata
Computer-Assisted Secondary Orbital Reconstruction (2020)

Outcomes of this study suggest that secondary orbital reconstruction can be performed routinely using selective laser-melted PSIs and titanium spacers.
Efficacy of newly discovered DNA aptamers targeting AXL in a lung cancer cell with acquired resistance to Erlotinib (2021)

We developed newly modified DNA aptamers that selectively bind to AXL receptors, and assessed their efficacy in a human lung cancer cell with acquired resistance to EGFR-TKI.
Biologics in Shoulder Surgery: The Role of Adult Mesenchymal Stem Cells in Tendon Repair (2007)

Successful treatment of chronic and large rotator cuff tears presents a challenge to the orthopaedic surgeon. There are times when no optimal reparative or reconstructive option exists, as in the case of massive or chronic rotator cuff tears, and “salvage” operations are the only reasonable surgical options. More recently is the emerging paradigm of utilizing adult mesenchymal stem cells (MSCs) and bioscaffolds to replace diseased or damaged tendon, cartilage, and bone. Over the last decade, there has been an explosion of literature defining the properties and potential role of adult MSC in the treatment of orthopaedic problems. Early evidence indicates that adult MSCs are capable of regenerating diseased tissue. Moreover, MSCs are easily obtainable and amplifiable with current tissue engineering technology, and they appear to be immunologically tolerated. Isolation and culture expansion of human MSCs will likely provide novel approaches to the treatment of many complex clinical problems. The present account reviews the current knowledge of mature MSCs as it relates to tendon healing. In addition, we present preliminary results of our investigations.
Potential of a Forestry Carbon Project for the Magbukun Ayta of Bataan, Philippines (2018)

The paper  discusses  the potential  of  developing  a forestry carbon project for  the Magbukun Ayta, an indigenous cultural community in the Philippines. The feasibilit y  of the forestry carbon project was evaluated based on technical, financial and social aspects. The results of thefeasibility analysis reveal that developing a forestry  carbon project for  the Magbukun Ay ta of Kanawan, Morang, Bataan is technically and financially feasible. The projected carbon loss in the ancestral domain due to possible deforestation in the old growth forest is a lot higher than expanding second growth forests and brush/ands, thus creating an excellent opportunity for the community to be engaged in a forestry  carbon project .  The NPV and IRR at the most conservative conditions (i.e., high scenario, price  of USD 5t   C02-1 and 20% discount rate) are PhP70 .728 million  (about USD 1.61 million) and 27%, respectively, which show that the forestry carbon project isfinancially viable. The Magbukun Ayta have also expressed in a resolution that they are amenable to the possibility of being involved in a PES project, specifically on the carbon sequestration potential of their forests, making the forestry carbon project socially acceptable. Likewise, the community's experience with implementing projects and contracts and benefit-sharing  and conflict resolution mechanisms place  the community in an advantageous position to implement this project . Thus, the project is socially feasible and acceptable. It is therefore recommended that the Magbukun Ayta engage in a forestry carbon project under the voluntary carbon market mechanism.
High-Performance Polyimide-Based Water–Solid Triboelectric Nanogenerator for Hydropower Harvesting (2021)

Water-solid triboelectric nanogenerators (TENGs) are insensitive to ambient humidity, providing a wide range of possibilities for designing stable water-energy-based harvesters and self-powered sensors. However, the wide application of most water-solid TENGs has been limited by low triboelectrification performance. To boost the output performance of water-solid TENGs, a newly structured TENG has been developed by adding a polyimide (PI) as a charge storage intermediate layer between the friction layer and the conducting layer, significantly improving the output performance (1.260 mW), with a 5-fold increase compared to the water-solid TENG without the PI intermediate layer (0.234 mW). This analysis shows that adding an intermediate layer with a high density of electron capture sites to the TENG results in more triboelectric charge being retained, thereby improving the electrical performance of TENG. The electrical performance of TENG is related to the thickness of the PI layer, but this is not a positive correlation. Contact angles and falling heights between the droplet and the device also affect the output performance. Finally, the water-solid PI-TENG we have developed has promise in hydropower harvesting capabilities and can be used to power warning signals on a dark and rainy night to ensure the safety of people.
Matched Spectral-Null Code with Run-Length Limitation for Optical Recording Channels (2009)

High track-density recording and multi-layer recording have been investigated for large capacity optical recording discs. In this case, the recorded data will be reproduced under the low signal-to-noise ratio (SNR) condition due to crosstalk from the adjacent tracks or the other layers, and robust data detection will be required. In this paper, a novel matched spectral-null (MSN) code providing the property of run-length limitation (RLL) was described considering the optical recording channels. Trellis Coded partial response maximum likelihood (TCPRML) employing the MSN code with RLL was also proposed for the data detection method enhancing the minimum Euclidian distance. The detection performance was estimated through the simulation model, which emulates the optical recording channels based on the blu-ray disc (BD) specification.
Effect of Annealing on the Electrical and Optical Properties of MgZnO Films Deposited by Radio Frequency Magnetron Sputtering (2020)

The properties of phase‐separated MgZnO induced by heat treatment are investigated, because the electrical conductivity of MgZnO deposited by sputtering can be improved by heat treatment. The absorption edge shows a red shift, but the transmittance in the ultraviolet (UV)‐C region increases after heat treatment. This is due to the formation of wurtzite (WZ) MgZnO with a high Zn content and a rock salt (RS) structure with a low Zn content induced by phase separation. This suggests that the current path is formed by the WZ crystals with low resistivity, and the transmittance in the UV region is increased by the RS crystals with high transmittance. It is confirmed that the RS structure is partially mixed with the WZ crystal in the in‐plane direction. In contrast, different distributions of crystals are observed in the stacking direction. A WZ structure is formed after RS‐MgZnO is formed on the substrate interface. It is found that Mg is incorporated into the RS structure by heat treatment, and Mg‐rich MgZnO is formed.
Pharmacotherapy for Neurogenic Detrusor Overactivity (2006)

Chancellor MB, Anderson RU, Boone TB: Pharmacotherapy for neurogenic detrusor overactivity. Am J Phys Med Rehabil 2006;85:536-545. Patients with neurogenic detrusor overactivity are a heterogeneous group with voiding dysfunction secondary to neurologic injury or disease. The neurogenic detrusor overactivity syndrome, which may include urinary frequency, urgency, and incontinence, frequently contributes to a loss of independence, or even institutionalization. Urodynamic assessment provides the best method of quantifying and classifying neurogenic detrusor overactivity dysfunction in patients with primary diagnoses as diverse as Parkinson's disease, cerebral palsy, multiple sclerosis, spinal cord injury, and spina bifida. For many patients, management of urinary symptoms includes pharmacotherapy with an anticholinergic agent. Several novel approaches to managing neurogenic detrusor overactivity, including intravesical instillation of anticholinergic agents, vanilloids, and neurotoxins, are being investigated. For most patients, however, flexible dosing with an anticholinergic agent, with clean intermittent catheterization when indicated, has been shown to reduce the risks of urologic complications, improve levels of continence, and enhance patient quality of life in both children and adults.
A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes (2022)

Our findings reflect the exceptional level of genomic resolution present in this assembly, which will greatly expand the potential of the Nile rat as a model organism.
A Repetitive Structure in the Chick 2-Collagen Gene (1981)

The collagens are a family of proteins that constitute the major protein component of the extracellular matrix in animal tissues (for reviews, see Ramachandran and Reddi 1976; Prockop et al. 1979a,b; Eyre 1980). At least five distinct types of collagen are found, all of which show a similar overall structure. The major features of this characteristic structure include the following: presence of glycine residues every third amino acid; abundance of prolines and lysines, many of which are hydroxylated; characteristic configuration of the molecule composed of three subunits that interact with each other to form a triple helical structure; presence of many inter- and intramolecular covalent cross-links resulting in a higher-order structural organization. The primary structure of the collagens varies, however, and probably reflects their different tissue-related functions. It is very likely that the synthesis of each of the collagens responds to a specific tissue-related differentiation program.
Low-Intensity Pulsed Ultrasound Accelerates Maturation of Callus in Patients Treated with Opening-Wedge High Tibial Osteotomy by Hemicallotasis (2004)

We found that low-intensity pulsed ultrasound applied during the consolidation phase of distraction osteogenesis accelerates callus maturation after opening-wedge high tibial osteotomy by hemicallotasis in elderly patients.
Understanding the Surface Structure of LiNi0.45Mn1.55O4 Spinel Cathodes with Aberration-Corrected HAADF STEM (2014)

In order for Li-ion batteries to mature to a level useful for integration into the current or future energy infrastructure, basic problems such as cyclability, cost and rate capability must be overcome. LiNi 0.5 Mn 1.5 O 4 (LNM), a spinel cathode material, has the advantage of being both cost-effective and a high-rate capable material, but it is plagued with cyclability problems. In the LNM system the main contributor to cycling degradation is the high operating voltage which leads to solid-electrolyte interphase (SEI) formation. We find that excess-Mn doping of this material (LiNi 0.5-X Mn 1.5+X O 4 where x=0.05) leads to increased cyclability through natural passivation [1]. To understand the exact role that excess Mn plays in the passivation of this cathode material, it is crucial to determine the surface’s atomic structure. This is because the surface structure determines how reactive the cathode will be with the electrolyte during oxidation and reduction cycles. In order to understand how excess-Mn LNM reacts with the electrolyte, it is critical to understand the different phases that form in this system. In this regard, aberration-corrected high-angle annular dark-field (HAADF) scanning transmission electron microscopy (STEM) was used to identify the surface and bulk structures in the excess-Mn LNM system. A HAADF STEM image of LiNi 0.45 Mn 1.55 O 4 along the [110] zone axis is shown in Figure 1. The image has been deconvoluted for clarity. This confirms the spinel structure (blue) and shows good agreement with STEM simulations in the bulk. Near the surface however, other phases are observed which include the rock-salt phase (green) and an unexpected phase defined here as “ring-type” (red). The rock-salt structure is expected from x-ray diffraction (XRD) results but the ring-type phase; so-called because of the characteristic rings that are formed within the first few atomic surface layers, is not. All three phases are observed near the surface, however only the spinel is found within the bulk of the particles. HAADF STEM enables a detailed characterization of these phases and has led to an important understanding of the cycling degradation mechanisms in the excess-Mn LNM system. In turn, this work enables us to develop a well-suited cathode material for future energy storage that will potentially spur the evolution of the future sustainable energy landscape. References: [1] J. Song et al., Chem. Mater. 24 (2012), 3101. Figure 1
Targeted delivery of acid alpha-glucosidase corrects skeletal muscle phenotypes in Pompe disease mice (2020)

Abstract Lysosomal diseases are a class of genetic disorders predominantly caused by loss of lysosomal hydrolases, leading to lysosomal and cellular dysfunction. Enzyme Replacement Therapy (ERT), where recombinant enzyme is given intravenously, internalized by cells, and trafficked to the lysosome, has been applied to treat several lysosomal diseases. However, current ERT regimens do not correct disease phenotypes in all affected organs because the biodistribution of enzyme uptake does not match that of the affected cells and tissues that require the enzyme. We present here targeted ERT, an approach that utilizes antibody-enzyme fusion proteins to target the enzyme to specific tissues. The antibody moiety recognizes transmembrane proteins involved in lysosomal trafficking and that are also preferentially expressed in those cells most affected in disease. Using Pompe disease (PD) as an example, we show that targeted ERT is superior to ERT in treating the skeletal muscle phenotypes of PD mice.
Two-Phase Calibration for a Mirror Metaphor Augmented Reality System (2014)

According to the ways to see the real environments, mirror metaphor augmented reality systems can be classified into video see-through virtual mirror displays and reflective half-mirror displays. The two systems have distinctive characteristics and application fields with different types of complexity. In this paper, we introduce a system configuration to implement a prototype of a reflective half-mirror display-based augmented reality system. We also present a two-phase calibration method using an extra camera for the system. Finally, we describe three error sources in the proposed system and show the result of analysis of these errors with several experiments.
Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces (2012)

Designing materials to control biology is an intense focus of biomaterials and regenerative medicine research. Discovering and designing materials with appropriate biological compatibility or active control of cells and tissues is being increasingly undertaken using high throughput synthesis and assessment methods. We report a relatively simple but powerful machine-learning method of generating models that link microscopic or molecular properties of polymers or other materials to their biological effects. We illustrate the potential of these methods by developing the first robust, predictive, quantitative, and purely computational models of adhesion of human embryonic stem cell embryoid bodies (hEB) to the surfaces of a 496-member polymer micro array library.
Carbonization of Disclike Molecules in Porous Alumina Membranes: Toward Carbon Nanotubes with Controlled Graphene‐Layer Orientation (2005)

Graphitische Kohlenstoffnanoröhren aus Graphenschichten, die senkrecht zur Röhrenachse orientiert sind (siehe Bild; der Pfeil zeigt die Achse an), wurden durch schrittweise Verkokung vororganisierter scheibenförmiger Moleküle in einem porösen Aluminiumoxidtemplat erhalten. Die Ausrichtung der Schichten sowie Größe, Wandstärke und Form der Röhren konnten auf diesem Weg eingestellt werden.
An efficient physical layer security algorithm for two-way relay systems (2016)

In this paper, we study the physical layer security in a two-way relay system consisting of two transceivers, one eavesdropper, and multiple relays. We study the system in case of the channel state information (CSI) of the eavesdropper is unknown, and hence artificial noise is used to degrade the signal to noise ratio at the eavesdropper. In order to reserve the maximum possible power for artificial noise, we consider the problem of minimizing the total power of the information signal transmitted by the relays, under quality of service constraints at the legitimate transceivers. This problem has been solved using semidefinite programming (SDP) and second order cone programming (SOCP) methods. Here, aiming to significantly decrease the complexity, we propose a novel approach to find the optimal solution using the generalized eigenvalue. We show that in most cases, we can provide a closed-form expression of the optimal solution. In addition, our proposed solution can be used for all quadratically constrained quadratic programs (QCQPs) with positive definite objective function and two constraints. Simulation results demonstrate the effectiveness of our algorithm in terms of optimality and low complexity compared to SDP.
Autonomous flight and cooperative control for reconstruction using aerial robots powered by smartphones (2018)

Advances in consumer electronics products and the technology seen in personal computers, digital cameras, and smartphones phones have led to the price/performance ratio of sensors and processors falling dramatically over the last decade. In particular, many consumer products are packaged with small cameras, gyroscopes, and accelerometers, all sensors that are needed for autonomous robots in GPS-denied environments. The low mass and small form factor make them particularly well suited for autonomous flight with small flying robots. In this work, we present the first fully autonomous smartphone-based system for quadrotors. We show how multiple quadrotors can be stabilized and controlled to achieve autonomous flight in indoor buildings with application to smart homes, search and rescue, monitoring construction projects, and developing models for architecture design. In our work, the computation for sensing and control runs on an off-the-shelf smartphone, with all the software functionality embedded in a smartphone app. No additional sensors or processors are required for autonomous flight. We are also able to use multiple, coordinated autonomous aerial vehicles to improve the efficiency of our mission. In our framework, multiple vehicles are able to plan safe trajectories avoiding inter-robot collisions, while concurrently building in a cooperative manner a three-dimensional map of the environment. The work allows any consumer with any number of robots equipped with smartphones to autonomously drive a team of quadrotor robots, even without GPS, by downloading our app and cooperatively build three-dimensional maps.
PD-1 Blockade with Cemiplimab in Advanced Cutaneous Squamous-Cell Carcinoma (2018)

Among patients with advanced cutaneous squamous-cell carcinoma, cemiplimab induced a response in approximately half the patients and was associated with adverse events that usually occur with immune checkpoint inhibitors. (Funded by Regeneron Pharmaceuticals and Sanofi; ClinicalTrials.gov numbers, NCT02383212 and NCT02760498 .).
Preparation via Diastereoselective Hydrogenation, Absolute Conformation and Configuration of Exogeneous Anabolic Zeranol ((3S, 7R)‐3,4,5,6,7,8,9,10,11,12‐Decahydro‐7,14,16‐trihydroxy‐3‐methy‐1H‐2‐benzoxacyclotetradecin‐1‐one) (1986)

Abstract Hydrogenation of the ketone group in di‐ O ‐benzylderivative ( 8 ) of the known macrocyclic lactone zeralenone ( 7 ) using a novel chiral borane complex 3 . BH 3 , prepared in situ , proceeded at lower temperatures with moderate diastereoselectivity (∼40%, d. e. at −60°). Unsaturated diastereomers 9 and 10 were separated, and 9 converted into zeranol ( 11 ), a known anabolic agent. Restricted conformational mobility at lower temperatures is assumed for the intermediate 8 on the basis of the temperature‐dependent CD spectra of its acetyl congeners 18 and 19 . X‐Ray structure analysis of 7‐ O ‐acetylderivative ( 13 ) of 11 revealed the ( R )‐configuration at C(7). Two crystallographically independent H 2 O molecules are involved in the H‐bonds, one of them (O(21)) rises the helices of the molecules of 13 along b. Small positive torsional angle [C(16)‐]C(161)‐C(1) [=O] (+19.3°), transoid ( E ) conformation of the lactone group, and nearly achiral arrangement of the C(11)‐C(12) bond (torsional angle [C(11)‐]C(12)‐C(121)[C(161)] is −93°) are the main conformational features that differentiate the macrocylic RAL (resorcinic‐acid lactone) derivatives from the 6‐membered lactone derivative 20 , studied earlier by CD. Consequently, the rules developed for the CD effects within conjugation band (around 270 nm), and n→π* band (around 255 nm) of the latter compound, cannot be applied the macrocyclic lactones.
ChemInform Abstract: The Transition‐Metal Cyclidenes: A Broad Family of Complexes Well Suited to Inclusion Chemistry (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Higher rates of carbapenem‐related seizures in older hospitalised adults (2020)

Clinical experience suggests higher occurrence of carbapenem-associated seizures in the elderly than what is reported in the available literature (range between 0.2% and 0.7%). An audit of 1345 patients with age 60 years or older, who received imipenem, ertapenem or meropenem during their acute hospitalisation found 32 (2.4%) subjects developed seizures. Subjects with more than one central nervous system disorders were 11.6 times more likely to develop seizures (odds ratio 11.61, P < 0.001) and subjects with prior history of seizures is associated with four times greater risks (odds ratio 4.02, P = 0.005). Physicians should exercise caution when prescribing carbapenems in elderly, especially those with known epilepsy and a high number of intracranial pathologies.
The Mechanism of DAB2IP in Chemoresistance of Prostate Cancer Cells (2013)

This study unveils a new regulation of the Egr-1/Clusterin signaling network by DAB2IP. Loss of DAB2IP expression in CRPC cells signifies their chemoresistance. Clusterin is a key target for developing more effective CRPC therapy.
Phenol chemisorption onto phthalocyanine thin layers probed by ATR-FTIR difference spectroscopy (2009)

Attenuated total reflection Fourier transform infrared (ATR-FTIR) difference spectroscopy has been employed as a powerful method for the comprehension of active layer-analyte interactions, revealing interesting mechanistic aspects concerning the binding of halogen-substituted phenols onto phthalocyanine Langmuir-Schaefer films.