gebhart/patrepeval huggingface dataset:
Cross polarization in the tilted frame: assignment and spectral simplification in heteronuclear spin systems (1998)

A frequency selective heteronuclear polarization transfer technique is introduced for rotating solids. In this method, radiofrequency fields comparable with the frequency offsets are applied to establish Hartmann-Hahn cross polarization that therefore depends explicitly on the resonance offset of the nuclei involved. Under these conditions, spectrally induced filtering in combination with cross polarization (SPECIFIC CP) can be achieved and is demonstrated to be useful for spectral simplification or assignment in heteronuclear spin pairs. The design principles are outlined and demonstrated experimentally on 13C, 15N labelled amino acids.
GTP-Eu binding assay optimization for the adenosine A3 receptor ligands screening (2010)

Since biological assays are essential in the early development of new drugs, there is increasing request of easy, robust, and not radioactive assays. GTP-Eu binding assay is a new no-radioactive tool produced by Perkin-Elmer company to screen compounds active at G-protein-coupled receptors [1]. This methodology can be considered a valid and powerful alternative to the well-known [35S]GTPγS binding assay, and it is based on the time-resolved fluorometry technique that exploits the fluorescence properties of lanthanide chelate europium. The aim of this work was the application and optimization of this procedure at adenosine A3 Gαi-coupled receptor in order to test new ligand activity with an assay endowed with high&#13;\nsensitivity, long shelf life, amenability to automation, and safety.
Guest editorial broadband access networks: architectures and protocols (2009)

The 13 papers in this special issue cover a diversity of topics on the design of network architectures and protocols for passive optical networks (PONs), WiMAX networks, and integrated optical and wireless access networks.
Using Color In Computer Applications: A Psychophysical Perspective (1994)

Deciding how to use color in computer applications is a very difficult problem. Some of the difficulty resides in the characterizing the output medium. Color production systems vary in their underlying color models, their intrinsic color gamuts, and even the angular distribution of the light stimulus reaching the human observer. Some of the difficulty resides in understanding the human perceptual system which is receiving this input. Perhaps most elusive of the difficulties, however, is how the interaction between the physical stimulus and the observer depends on the task the user is trying to perform.
Experimental Verification of Deep Field Weakening Operation of a 50-kW IPM Machine by Using Single Current Regulator (2010)

This paper analyzes critical control issues associated with the deep field weakening operation of interior permanent magnet (IPM) synchronous machines. The singlecurrent-regulator control algorithm is reviewed, which controls the <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">d</i> -axis current actively and gives a fixed <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">q</i> -axis voltage command. To achieve better operational efficiency and performance, improvements are made to choose an optimal <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">q</i> -axis voltage for variable-speed and variable-load conditions. The control algorithm is implemented on a 50-kW IPM machine. Test results, including 7:1 constant power speed ratio operation, are presented to verify the theoretical analysis.
Advanced Surveying Techniques Help Increase Hydrocarbons Production While Preventing Well Collisions and HSE Risks (2013)

Abstract Continued growth in worldwide demand for oil and gas has encouraged operators in Latin America to develop reservoirs using wells drilled from congested pads. Without remedial action, this practice would lead to operational or HSE risks, both on land and offshore. An oilfield service company has adopted a comprehensive approach to this issue by incorporating a methodology for planning and preventing the risk of well-to-well collisions while drilling in congested environments. This anticollision methodology has been used to drill thousands of wells in Latin America without the occurrence of collision events. Along with the anticollision methodology, the development and use of advanced surveying techniques allows the placement of complex horizontal and 3D wells in congested land and offshore fields. Multiple case histories support the functionality and effectiveness of the anticollision methodology. These case histories are from operations developed in different countries and include drilling in congested offshore environments. The focus of the methodology is safety of personnel and preventing HSE incidents.
Data from Integrative Genomic Analysis Implicates Gain of <i>PIK3CA</i> at 3q26 and <i>MYC</i> at 8q24 in Chronic Lymphocytic Leukemia (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; The disease course of chronic lymphocytic leukemia (CLL) varies significantly within cytogenetic groups. We hypothesized that high-resolution genomic analysis of CLL would identify additional recurrent abnormalities associated with short time-to-first therapy (TTFT).&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; We undertook high-resolution genomic analysis of 161 prospectively enrolled CLLs using Affymetrix 6.0 SNP arrays, and integrated analysis of this data set with gene expression profiles.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; Copy number analysis (CNA) of nonprogressive CLL reveals a stable genotype, with a median of only 1 somatic CNA per sample. Progressive CLL with 13q deletion was associated with additional somatic CNAs, and a greater number of CNAs was predictive of TTFT. We identified other recurrent CNAs associated with short TTFT: 8q24 amplification focused on the cancer susceptibility locus near &lt;i&gt;MYC&lt;/i&gt; in 3.7%; 3q26 amplifications focused on &lt;i&gt;PIK3CA&lt;/i&gt; in 5.6%; and 8p deletions in 5% of patients. Sequencing of &lt;i&gt;MYC&lt;/i&gt; further identified somatic mutations in two CLLs. We determined which catalytic subunits of phosphoinositide 3-kinase (PI3K) were in active complex with the p85 regulatory subunit and showed enrichment for the α subunit in three CLLs carrying &lt;i&gt;PIK3CA&lt;/i&gt; amplification.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Our findings implicate amplifications of 3q26 focused on &lt;i&gt;PIK3CA&lt;/i&gt; and 8q24 focused on &lt;i&gt;MYC&lt;/i&gt; in CLL. &lt;i&gt;Clin Cancer Res; 18(14); 3791–802. ©2012 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
The Roots of Autism and ADHD Twin Study in Sweden (RATSS) (2014)

Neurodevelopmental disorders affect a substantial minority of the general population. Their origins are still largely unknown, but a complex interplay of genetic and environmental factors causing disturbances of the central nervous system's maturation and a variety of higher cognitive skills is presumed. Only limited research of rather small sample size and narrow scope has been conducted in neurodevelopmental disorders using a twin-differences design. The Roots of Autism and ADHD Twin Study in Sweden (RATSS) is an ongoing project targeting monozygotic twins discordant for categorical or dimensional autistic and inattentive/hyperactive-impulsive phenotypes as well as other neurodevelopmental disorders, and typically developing twin controls. Included pairs are 9 years of age or older, and comprehensively assessed for psychopathology, medical history, neuropsychology, and dysmorphology, as well as structural, functional, and molecular brain imaging. Specimens are collected for induced pluripotent (iPS) and neuroepithelial stem cells, genetic, gut bacteria, protein-/monoamine, and electron microscopy analyses. RATSS's objective is to generate a launch pad for novel surveys to understand the complexity of genotype-environment-phenotype interactions in autism spectrum disorder and attention-deficit hyperactivity disorder (ADHD). By October 2013, RATSS had collected data from 55 twin pairs, among them 10 monozygotic pairs discordant for autism spectrum disorder, seven for ADHD, and four for other neurodevelopmental disorders. This article describes the design, recruitment, data collection, measures, collected pairs' characteristics, as well as ongoing and planned analyses in RATSS. Potential gains of the study comprise the identification of environmentally mediated biomarkers, the emergence of candidates for drug development, translational modeling, and new leads for prevention of incapacitating outcomes.
Table S2 from JQ1 Induces DNA Damage and Apoptosis, and Inhibits Tumor Growth in a Patient-Derived Xenograft Model of Cholangiocarcinoma (2023)

&lt;p&gt;Gene products downregulated greater than or equal to 2.4-fold by JQ1 in CCA1 tumors.&lt;/p&gt;
Photocatalytic CO2 reduction by TiO2 and related titanium containing solids (2012)

The shortage of fossil fuels and the need to find alternative renewable and sustainable fuels for transportation are triggering an increasing interest in the photocatalytic reduction of CO2. In this review, we have focused on titanium containing photocatalysts that effect the reduction of CO2 to fuels. The various products that are more generally formed are CH4, CH3OH, CO as well as HCOOH. This review has been organized primarily depending on the type of titanium material used as the photocatalyst. The list includes pure TiO2 as well as metal- and non metal-doped titania, noble metals supported on titania and micro-/mesoporous titanosilicates or porous matrices containing titania clusters. In a general introduction we comment on the limitations of the current approaches and the various possibilities and conditions for performing the irradiation. In a final section, we also give our view on future developments and open issues to be addressed in this field.
Aberrant methylation of trail decoy receptor genes is frequent in multiple tumor types (2004)

TNF-related apoptosis-inducing ligand (TRAIL) selectively induces programmed cell death (apoptosis) in various cancer cells but not in normal cells. TRAIL is known to bind to 4 different receptors, 2 proapoptotic (DR4 and DR5), and 2 potentially antiapoptotic receptors lacking death domains (DcR1 and DcR2). Aberrant promoter methylation and resultant silencing of tumor suppressor genes play an important role in the pathogenesis of many tumor types. Recently aberrant methylation of TRAIL decoy receptors was reported in pediatric tumor cell lines and neuroblastomas. We examined the methylation and expression status of TRAIL receptor genes in cancers of breast, lung, mesothelioma, prostate, bladder, cervix, ovary, brain and in hematopoietic malignancies. Aberrant methylation of DcR1 or DcR2 was present in 70% of primary breast cancers, 31% of primary lung cancers, in 63% of primary malignant mesothelioma (MM), in 60% of prostate cancer, in 42% of bladder cancer, in 100% of cervical cancer, in 43% of ovarian cancer, in 41% of lymphoma, in 26% of leukemia and in 56% of multiple myeloma. Methylation of DR4 and DR5 was rare in all the tumor types examined. Methylation of all the 4 receptors was rare in non malignant tissues. In cell lines, aberrant methylation of DcR1 was present in 11 of 23 (48%) breast, 10 of 27 (37%) lung and 3 of 7 (43%) MM, whereas aberrant methylation of DcR2 was present in 17 of 23 (74%) breast, 13 of 27 (48%) lung and 5 of 7 (71%) MM. The concordance between loss of gene expression and aberrant methylation ranged from 70-100%. Treatment with 5-aza-2'-deoxycytidine restored DcR1 and DcR2 expression in 9 methylated cell lines confirming that aberrant methylation was the cause for silencing of DcR1 and DcR2 expression. Our results demonstrate that DcR1 and DcR2 genes are frequently methylated in various tumor types, and that the role of decoy receptors in tumor pathogenesis needs to be re-evaluated.
Electric field control of magnetic anisotropy in bilayer contacts with Rashba-type spin–orbit interaction (2017)

Theoretical analysis of the uniaxial magnetic anisotropy (MA) in bilayer contacts composed of a non-magnetic layer with Rashba-type spin–orbit interaction and a ferromagnetic one with L − S coupling has been performed. The Rashba-type spin–orbit interaction contributes to the MA of the bilayer via band-mixing of the Rashba-split conduction band of the non-magnetic layer and the exchange-split bands of the ferromagnetic layer. Numerical results of a simple model show that the Rashba-induced MA could have the same order of magnitude as the MA produced in the ferromagnetic layer, indicating that the electric-field dependence of the Rashba spin–orbit interaction may be used to control the uniaxial MA in bilayer contacts.
Gas-liquid chromatography of derivatized barbiturates: An undergraduate experiment (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGas-liquid chromatography of derivatized barbiturates: An undergraduate experimentM. Novotny and K. D. Bartl Cite this: J. Chem. Educ. 1974, 51, 5, 333Publication Date (Print):May 1, 1974Publication History Received3 August 2009Published online1 May 1974Published inissue 1 May 1974https://doi.org/10.1021/ed051p333Request reuse permissionsArticle Views89Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alertsclose Get e-Alerts
Supplementary Figure 2 from Tumor Suppressor Functions of miR-133a in Colorectal Cancer (2023)

&lt;p&gt;PDF file - 54K, miR-133a expression levels in xenograft models.&lt;/p&gt;
Non-alcoholic fatty liver disease-associated hepatocellular carcinoma: effect of hepatic steatosis on major hepatocellular carcinoma features at MRI (2018)

In patients with non-cirrhotic, non-alcoholic fatty liver disease (NAFLD)-associated hepatocellular carcinoma (HCC), absent HCC washout and capsule appearance are associated with increasing hepatic steatosis, thereby potentially impacting the noninvasive imaging diagnosis of HCC in these patients. Lack of washout or capsule appearance in steatotic livers at MRI may require alternative criteria for the diagnosis of HCC in patients with non-cirrhotic NAFLD.
Effects in vitro of progesterone and two 5α‐reduced progestins, 5α‐pregnane‐3,20‐dione and 5α‐pregnane‐3α‐ol‐20‐one, on contracting human myometrium at term (1992)

Progesterone is known to prevent labour at term in domestic animals, but its effect in primates is uncertain. 5 alpha-reduced progesterone metabolites are more potent central nervous system depressants than progesterone is itself. Progesterone and its 5 alpha-reduced metabolites also relax pregnant rat myometrium in vitro. The serum concentration of the initial 5 alpha-reduced metabolite, 5 alpha-pregnane-3,20-dione, is high during pregnancy, but decreases significantly prior to parturition. The next metabolite, 5 alpha-pregnane-3 alpha-ol-20-one, has anaesthetic properties in human beings. The purpose of this study was to ascertain whether these progesterone metabolites also suppress contracting human uterine muscle at term. An in vitro model was devised. Strips of human myometrial muscle were mounted in organ chambers and after regular contractions had become established, the strips were superfused with progestin solutions. The progestins were dissolved in the buffer using an ultrasound bath. Progesterone, used as reference substance, slightly reduced the measured amount of muscular work performed per contraction, recordable after 18 min of exposure (p less than 0.05). Similar results have been reported previously in the literature; 5 alpha-pregnane-3 alpha-ol-20-one showed the same tendency though not significant at the 5% level. 5 alpha-pregnane-3,20-dione evidently reduced the contraction frequency after 10 min of exposure (p less than 0.05). None of the substances affected the duration of the contraction. These 5 alpha-reduced progesterone metabolites are thus not potent inhibitors of contracting human term myometrium in vitro.
Ultraviolet and visible resonance-enhanced Raman scattering in epitaxial Al1−xInxN thin films (2001)

We report the observation of ultraviolet and visible near-resonance enhanced Raman scattering in epitaxial wurtzite Al1−xInxN (0001) (0⩽x&amp;lt;0.7) thin films. The films (thickness∼150 nm) were grown by plasma source molecular beam epitaxy on sapphire (0001) substrates. A substantial spectral enhancement is seen for Al-rich samples using 244 nm (5.01 eV) radiation due to the closeness of their band gap energy to the excitation energy. On the other hand, samples with x∼0.6 (energy band gap ∼2.5 eV) show significant enhancement with 514.5 nm (2.41 eV) excitation. The A1(LO) and E2 zone center phonons have been observed for all the samples. The A1(LO) phonon frequency shows the expected decrease with increasing x. The E2 mode shows a two-mode behavior supporting the recent theoretical predictions. Due to increased resonance enhancement, strong second- and third-order spectra are seen in some films.
Effect of dietary fat on individual long‐chain fatty acyl‐CoA esters in rat liver and skeletal muscle (1989)

The effect of dietary fat on the long-chain acyl-CoA ester profile of liver and skeletal muscle was investigated by feeding weanling rats 12%-fat diets composed of high-linoleic safflower oil (73% 18:2n-6), high-oleic safflower oil (70% 18:1n-9) or olive oil (70% 18:1n-9) for six and ten weeks. Approximately 50% of both hepatic and skeletal muscle acyl-CoA esters comprised linoleoyl-CoA or oleoyl-CoA with high-linoleic or oleic feeding, respectively. Total hepatic acyl-CoA ester concentration was 40% higher (p less than 0.05) in rats fed 12% fat compared with controls fed a 4%-fat diet. These data demonstrate that the long-chain acyl-CoA ester profile of liver and skeletal muscle reflects the dietary fatty acid profile.
Insect Suppression with Controlled Release Pheromone Systems: Volume II (2017)

Insect suppression with controlled release pheromone systems , Insect suppression with controlled release pheromone systems , کتابخانه دیجیتالی دانشگاه علوم پزشکی و خدمات درمانی شهید بهشتی
Correlation Between Bone Mineral Density and Intervertebral Disc Degeneration (1998)

According to the results of the analysis by disc morphology and bone mass, especially total body bone mineral density, bone mass has an inverse correlation to intervertebral disc degeneration--i.e., reduction and disc bulge--which is important when considering degenerative spinal diseases and osteoporosis.
Bright Phosphorescence of All-Organic Chromophores Confined within Water-Soluble Silica Nanoparticles (2019)

Room temperature phosphorescence is usually a prerogative of metal complexes. Molecules with a hexakis(phenylthio)benzene core constitute a rare example of all-organic chromophores with phosphorescence induced by environmental rigidification. Here we report covalent encapsulation of functionalized persulfurated benzene chromophores into silica nanoparticles as a method of rigidification for induction of phosphorescence. The developed nanoparticles display bright phosphorescence at ambient temperatures and possess high colloidal stability in water. The method permits incorporation of a large number of chromophores (ca. 40) per nanoparticle while preserving their emissivity. The luminescence of the nanoparticles is sensitive to quenching by molecular oxygen in the physiological oxygen range, potentially making them suitable as probes for phosphorescence lifetime imaging of oxygen in biological systems.
Resistance Gene-Dependent Plant Defense Responses (1996)

Kim E. Hammond-Kosack, Jonathan D. G. Jones, Resistance Gene-Dependent Plant Defense Responses, The Plant Cell, Vol. 8, No. 10, Special Review Issue on Plant-Microbe Interactions (Oct., 1996), pp. 1773-1791
Coupled photonic crystal microcavity array laser (2005)

We designed a new laser composed of two-dimensional coupled photonic crystal microcavity arrays. In these structures we have observed single mode lasing with power conversion efficiency 10 times better than a single microcavity laser
CCDC 204141: Experimental Crystal Structure Determination (2004)

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Broad-band two-dimensional Fourier transform ion cyclotron resonance (1988)

Two-dimensional (2D) Fourier transform ion cyclotron resonance (2D FT-ICR) allows one to obtain direct evidence for the occurrence of ion-mol. reactions. In 2D FT-ICR spectra, one observes resonances with 2 distinct frequency coordinates w1 and w2 that correspond to the mass-to-charge ratios of the ions that participate as reactants and products, resp. It is possible to monitor a manifold of distinct reactions in one single 2D spectrum. Spectral ranges of the order of several MHz can be covered by using frequency-swept (\\"chirped\\") radio-frequency pulses. [on SciFinder (R)]
Automotive Radar Interference Mitigation with Unfolded Robust PCA based\n on Residual Overcomplete Auto-Encoder Blocks (2020)

In autonomous driving, radar systems play an important role in detecting\ntargets such as other vehicles on the road. Radars mounted on different cars\ncan interfere with each other, degrading the detection performance. Deep\nlearning methods for automotive radar interference mitigation can succesfully\nestimate the amplitude of targets, but fail to recover the phase of the\nrespective targets. In this paper, we propose an efficient and effective\ntechnique based on unfolded robust Principal Component Analysis (RPCA) that is\nable to estimate both amplitude and phase in the presence of interference. Our\ncontribution consists in introducing residual overcomplete auto-encoder\n(ROC-AE) blocks into the recurrent architecture of unfolded RPCA, which results\nin a deeper model that significantly outperforms unfolded RPCA as well as other\ndeep learning models.\n
A comparison between various empirical models for TCAD purposes (2002)

In this paper we discuss some of the existing response surface modeling techniques currently used for TCAD purposes and bring to the readers' attention a Bayesian framework for training feed-forward neural networks. We assess the model performances of different models by studying a 0.25 /spl mu/m nMOS transistor. We show that the Bayesian learning neural network modeling may successfully replaces traditional models in particular cases.