gebhart/patrepeval huggingface dataset:
Augmenting max-weight with explicit learning for wireless scheduling with switching costs (2017)

In small-cell wireless networks where users are connected to multiple base stations (BSs), it is often advantageous to opportunistically switch off a subset of BSs to minimize energy costs. We consider two types of energy cost: (i) the cost of maintaining a BS in the active state, and (ii) the cost of switching a BS from the active state to inactive state. The problem is to operate the network at the lowest possible energy cost (sum of activation and switching costs) subject to queue stability. In this setting, the traditional approach - a Max-Weight algorithm along with a Lyapunov-based stability argument - does not suffice to show queue stability, essentially due to the temporal co-evolution between channel scheduling and the BS activation decisions induced by the switching cost. Instead, we develop a learning and BS activation algorithm with slow temporal dynamics, and a Max-Weight based channel scheduler that has fast temporal dynamics. We show using convergence of time-inhomogeneous Markov chains, that the co-evolving dynamics of learning, BS activation and queue lengths lead to near optimal average energy costs along with queue stability.
Triangulation based technique for efficient stereo computation in infrared images (2004)

This paper proposes a technique to compute an accurate semi-dense disparity map from infrared stereo image pairs obtained using an uncalibrated stereo rig. First, an initial sparse disparity map is obtained using corner matching methods. This map is then refined using our proposed triangular constraints and the epipolar geometrical constraints to yield a more accurate semidense disparity map. Experimental results obtained using the proposed method are reported along with results obtained with a classical correlation based method as well as a more recent method based on graph-cuts. The proposed method yields good results even with low resolution, low texture infrared images. The proposed method is designed to be part of a vision-based occupant sensing system that will help to control airbag deployment in future vehicles.
Thermo-chemical conversion of straw: Haloclean : a performance enhanced low temperature pyrolysis (2005)

Haloclean a performance enhanced low temperature pyrolysis for biomass developed by Forschungszentrum Karlsruhe and Sea Marconi Is closing the gap between classical and fast pyrolysis approaches. For pyrolysis of straw (chaffed-, finely ground and pellets) temperature ranges between 320 to 420°C and residence times of only 1 to 5 minutes can be realized. Liquid yields of up to 45 wt-% and 35 wt-% of solids are possible. Solid yields can be increased up to 73 wt-% while loosing 4.5 % of the feed energy by pyrolysis gases only. Toxicity tests of the fractions do not show relevant numbers.
Dissection of Antibody Responses of Gam-COVID-Vac-Vaccinated Subjects Suggests Involvement of Epitopes Outside RBD in SARS-CoV-2 Neutralization (2023)

Millions of people have been vaccinated with Gam-COVID-Vac but fine specificities of induced antibodies have not been fully studied. Plasma from 12 naïve and 10 coronavirus disease 2019 (COVID-19) convalescent subjects was obtained before and after two immunizations with Gam-COVID-Vac. Antibody reactivity in the plasma samples (n = 44) was studied on a panel of micro-arrayed recombinant folded and unfolded severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) proteins and 46 peptides spanning the spike protein (S) and by immunoglobulin G (IgG) subclass enzyme-linked immunosorbent assay (ELISA). The ability of Gam-COVID-Vac-induced antibodies to inhibit binding of the receptor-binding domain (RBD) to its receptor angiotensin converting enzyme 2 (ACE2) was investigated in a molecular interaction assay (MIA). The virus-neutralizing capacity of antibodies was studied by the pseudo-typed virus neutralization test (pVNT) for Wuhan-Hu-1 and Omicron. We found that Gam-COVID-Vac vaccination induced significant increases of IgG<sub>1</sub> but not of other IgG subclasses against folded S, spike protein subunit 1 (S1), spike protein subunit 2 (S2), and RBD in a comparable manner in naïve and convalescent subjects. Virus neutralization was highly correlated with vaccination-induced antibodies specific for folded RBD and a novel peptide (i.e., peptide 12). Peptide 12 was located close to RBD in the N-terminal part of S1 and may potentially be involved in the transition of the pre- to post-fusion conformation of the spike protein. In summary, Gam-COVID-Vac vaccination induced S-specific IgG<sub>1</sub> antibodies in naive and convalescent subjects in a comparable manner. Besides the antibodies specific for RBD, the antibodies induced against a peptide close to the N-terminus of RBD were also associated with virus-neutralization.
Robustaflavone, a naturally occurring biflavanoid, is a potent non-nucleoside inhibitor of hepatitis B virus replication in vitro (1997)

Robustaflavone, a naturally occurring biflavanoid isolated from the seed kernel extract of Rhus succedanea, was found to be a potent in vitro inhibitor of hepatitis B, with an effective concentration (EC50) of 0.25 μM and an in vitro selectivity index (IC50EC90) of 153. Further studies suggested that inhibition of HBV DNA polymerase is the mechanism of action.
Successful laparoscopic revision of distally obstructed ventriculo-peritoneal shunts (1994)

SummaryTwo patients with distally obstructed ventriculo-peritoneal shunts were successfully treated by laparoscopic intervention. A 72-year-old woman with normal pressure hydrocephalus and a 24-year-old woman with aqueductal stenosis became symptomatic because of distal obstructions of previously placed ventriculo-peritoneal shunts. Laparoscopic intervention enabled the efficient revision of the distal cannulae in both cases with prompt clinical improvement.
Fabrication of a CMOS-based Imaging Chip with Monolithically Integrated RGB and NIR Filters (2019)

Recent developments in multispectral cameras have demonstrated how compact and low-cost spectral sensors can be made by monolithically integrating filters on top of commercially available image sensors. In this paper, the fabrication of a RGB + NIR variation to such a single-chip imaging system is described, including the integration of a metallic shield to minimize crosstalk, and two interference filters: a NIR blocking filter, and a NIR bandpass filter. This is then combined with standard polymer based RGB colour filters. Fabrication of this chip is done in imec’s 200 mm cleanroom using standard CMOS technology, except for the addition of RGB colour filters and microlenses, which is outsourced.
Multiple-viewpoint projection holograms synthesized by spatially incoherent correlation with broadband functions (2008)

We present a theoretical framework for recording and reconstructing incoherent correlation holograms of real-existing three-dimensional scenes observed from multiple viewpoints. This framework is demonstrated by generating and reconstructing a modified Fresnel hologram as well as a new correlation hologram called a protected correlation hologram. The reconstructed scene obtained from the protected correlation hologram has a significantly improved transverse resolution for the far objects in the scene compared to the modified Fresnel hologram. Additionally, the three-dimensional information encoded into the protected correlation hologram is scrambled by a secretive point spread function and thus the hologram can be used for encrypting the observed scene. The proposed holography methods are demonstrated by both simulations and experiments.
Energy transfer processes along a supramolecular chain of π-conjugated molecules (2012)

We have investigated the energy transfer dynamics in a supramolecular linear polymer chain comprising oligofluorene (OF) energy donor units linked by quadruple hydrogen-bonding groups, and oligophenylene (OPV) chain ends that act as energy acceptors. Using femtosecond spectroscopy, we followed the dynamics of energy transfer from the main chain of OF units to the OPV chain ends and simulated these data taking a Monte Carlo approach that included different extents of electronic wave function delocalization for the energy donor and acceptor. Best correlations between experimental and theoretical results were obtained for the assumption of electronic coupling occurring between a localized donor dipole moment and a delocalized acceptor moment. These findings emphasize that geometric relaxation following initial excitation of the donor needs to be taken into account, as it leads to a localization of the donor's excited state wave function prior to energy transfer. In addition, our simulations show that the energy transfer from the main chain to the ends is dominated by an interplay between slow and spatially limited exciton migration along the OF segments comprising the main chain and the comparatively faster hetero-transfer to the end-cap acceptors from directly adjoining OF segments. These results clearly support the description of host–guest energy transfer in linear polymer chains as a two-step mechanism with exciton diffusion in the host being a prerequisite to energy transfer to the guest.
<title>Laser-induced thermal desorption studies of surface reaction kinetics</title> (1991)

Laser induced thermal desorption (LITD) has proven to be an effective probe of reaction kinetics on single-crystal surfaces. The ability of LITD techniques to measure adsorption, decomposition and desorption kinetics will be illustrated by studies of SiCl4 and (CH3CH2)2 SiH2 on Si(111)7X7. Silicon tetrachloride, SiCl4, is important in silicon epitaxial growth and diethylsilane, (CH3CH2)2 SiH2, is a promising candidate for silicon atomic layer epitaxy. The desorption products, sticking coefficients and decomposition and desorption kinetics measured by these LITD investigations are important for an understanding of silicon epitaxy by chemical vapor deposition.
Periodic Open Cellular Raney‐Copper Catalysts Fabricated via Selective Electron Beam Melting (2020)

Herein, the possibility of generating Raney‐Copper catalysts with high geometric complexity is demonstrated. For this, periodic open cellular structures (POCS) composed of a highly brittle Al–Cu alloy containing 29.4 at% copper are fabricated by selective electron beam melting (SEBM) for application in chemical reaction engineering. After selective leaching of aluminum in an NaOH solution, the POCS show a core–shell structure with a nanoporous copper surface layer and a solid core. The fabrication and dealloying processes as well as the microstructure are studied. Moreover, the SEBM‐processed Raney‐type copper catalysts show a high catalytic activity in methanol synthesis.
Proposal for a New Classification of Solutes of Interest in Uremia and Hemodialysis (2022)

Uremic toxins contribute to clinical manifestations of kidney dysfunction. These toxins include organic and inorganic elements or compounds. While the kidney typically clears uremic toxins, gut dysbiosis, and tissue inflammation could lead to increased production of substances that can further the clinical manifestations of uremia. The uremic toxins are quantitatively measurable in biological fluids and have an established relationship with azotemia signs and symptoms. Their elimination is associated with mitigated uremic manifestations, while their administration to the uremic levels leads to uremic signs in animal or human models or in vitro studies. Besides, the uremic toxins have an established and plausible pathophysiologic relationship with uremic manifestations. The previous classification of uremic toxins was mainly focused on the physicochemical characteristics of these substances to divide them into three categories, (1) free water-soluble low-molecular-weight (<500 Da) solutes, (2) protein-bound, water-soluble, low molecular weight (<500 Da), (3) middle molecular weight (>500 Da and <12,000 Da), and (4) high molecular weight (>12,000 Da). Unfortunately, the classification named above was not centered around patient outcomes and quality of life among those with severe kidney failure. Therefore, a panel of experts convened virtually to provide additional insights into the current state and propose a new uremic toxin classification. This article describes the group's consensus recommendations regarding the new classification of uremic toxins into more clinically oriented categories.
Hypovitaminosis D Is Prevalent in Patients With Renal AL Amyloidosis and Associated With Renal Outcome (2022)

Hypovitaminosis D is common in AL amyloidosis, particularly among patients with heavy proteinuria. Severe 25(OH)D deficiency at time of diagnosis predicts progression to ESRD.
Self-terminating contactless photo-electrochemical (CL-PEC) etching for fabricating highly uniform recessed-gate AlGaN/GaN high-electron-mobility transistors (HEMTs) (2021)

Contactless photo-electrochemical (CL-PEC) etching was used to fabricate recessed-gate AlGaN/GaN high-electron-mobility transistors (HEMTs). Self-termination of etching was observed during CL-PEC etching on an AlGaN barrier layer whose residual thickness had a uniform value of 6 nm overall on the same chip. After tetramethylammonium hydroxide post-treatment, the root-mean-square roughness of the etched surface was around 0.4 nm, which had smoothness comparable to that of the unetched surface. Recessed-Schottky HEMTs showed a positive shift in Vth, the suppression of drain leakage currents, and an improvement in the subthreshold-slope value as compared with planar-gate HEMTs. By applying a metal–insulator–semiconductor (MIS)-gate structure, the gate and drain leakage currents were significantly reduced, leading to an increased input dynamic range. Furthermore, the standard deviations (σ) of the Vth of CL-PEC-etched recessed-Schottky HEMTs and recessed-MIS HEMTs were very small, 5.5 and 16.7 mV, respectively. These results showed that the CL-PEC etching process is promising for the fabrication of recessed-gate AlGaN/GaN HEMTs having excellent uniformity for normally-off device operations.
Circular RNA vaccine induces potent T cell responses (2023)

Circular RNAs (circRNAs) are a class of RNAs commonly found across eukaryotes and viruses, characterized by their resistance to exonuclease-mediated degradation. Their superior stability compared to linear RNAs, combined with previous work showing that engineered circRNAs serve as efficient protein translation templates, make circRNA a promising candidate for RNA medicine. Here, we systematically examine the adjuvant activity, route of administration, and antigen-specific immunity of circRNA vaccination in mice. Potent circRNA adjuvant activity is associated with RNA uptake and activation of myeloid cells in the draining lymph nodes and transient cytokine release. Immunization of mice with engineered circRNA encoding a protein antigen delivered by a charge-altering releasable transporter induced innate activation of dendritic cells, robust antigen-specific CD8 T cell responses in lymph nodes and tissues, and strong antitumor efficacy as a therapeutic cancer vaccine. These results highlight the potential utility of circRNA vaccines for stimulating potent innate and T cell responses in tissues.
Synthetic Ovine Corticotropin-Releasing Hormone: Simultaneous Release of Proopiolipomelanocortin Peptides in Man* (1984)

The response of plasma proopiolipomelanocortin-derived peptide levels to synthetic ovine corticotropin-releasing hormone (CRH) was studied in six normal men. CRH was given as a 30-sec iv injection of 30 micrograms/kg body weight in the late afternoon, and blood samples were drawn for up to 16 h thereafter. Low levels of immunoreactive (IR)-ACTH, IR-beta-endorphin and IR-lipotropins (LPH) were measured before CRH administration. All subjects had prompt, concomitant, biphasic, and prolonged release of all of these proopiolipomelanocortin-derived peptides. The plasma levels of these IR-peptides rose in all subjects by 5 min after CRH, reached a first peak at 10-15 min, fell until 90 min, rose to a second peak at 2-4 h, and then gradually declined over several hours. The molar concentrations of the IR-peptides closely paralleled one another at all times, especially during the first 90 min after CRH administration. Later, IR-LPH increased slightly more and remained slightly higher than did the other IR-peptides, although the difference was not significant. This observation probably reflects the longer plasma disappearance half-life of IR-LPH. The maximum change (mean +/- SEM) in the concentration of these IR-peptides was similar: IR-ACTH, 18.0 +/- 4.0; IR-LPH, 20.5 +/- 4.0; and IR-beta-endorphin, 16.9 +/- 3.2 fmol/ml. The next morning's circadian rise in IR-peptides was blocked, presumably due to negative feedback inhibition of the hypothalamic-pituitary-adrenal axis by the prolonged high plasma cortisol levels stimulated by CRH the previous evening.
Time course of swept-source optical coherence tomography angiography findings after photodynamic therapy and aflibercept in eyes with age-related macular degeneration (2019)

SS-OCTA is useful to monitor the morphology of CNV after PDT and IVA, indicating that the remodeling of the choroidal vasculature occurs gradually after treatment. The presence or absence of the CNV signal might indicate CNV activity.
A min, + system theory for constrained traffic regulation and dynamic service guarantees (2002)

By extending the system theory under the (min, +) algebra to the time-varying setting, we solve the problem of constrained traffic regulation and develop a calculus for dynamic service guarantees. For a constrained traffic-regulation problem with maximum tolerable delay d and maximum buffer size q, the optimal regulator that generates the output traffic conforming to a subadditive envelope f and minimizes the number of discarded packets is a concatenation of the g-clipper with g(t) = min[f(t+ d), f (t)+q] and the maximal f-regulator. The g-clipper is a bufferless device, which optimally drops packets as necessary in order that its output be conformant to an envelope g. The maximal f-regulator is a buffered device that delays packets as necessary in order that its output be conformant to an envelope f. The maximal f-regulator is a linear time-invariant filter with impulse response f, under the (min, +) algebra. To provide dynamic service guarantees in a network, we develop the concept of a dynamic server as a basic network element. Dynamic servers can be joined by concatenation, "filter bank summation," and feedback to form a composite dynamic server. We also show that dynamic service guarantees for multiple input streams sharing a work-conserving link can be achieved by a dynamic service curve earliest deadline scheduling algorithm, if an appropriate admission control is enforced.
An X-ray Photoelectron Spectroscopy Study of Postsynthetic Exchange in UiO-66 (2022)

Postsynthetic exchange (PSE) is a method that is widely used to change the composition of metal-organic frameworks (MOFs) by replacing connecting linkers or metal nodes after the framework has been synthesized. However, few techniques can probe the nature and distribution of exchanged species following PSE. Herein, we show that X-ray photoelectron spectroscopy can be used to compare the relative concentrations of exchanged ligands at the surface and interior regions of MOF particles. Specifically, PSE of iodobenzene dicarboxylate ligands results in a gradient distribution from surface to bulk in UiO-66 nanoparticles that depends on PSE time. X-ray photoelectron spectroscopy also reveals differences between the surface chemistry of the PSE product and that of the direct synthesis product.
The MITLL NIST LRE 2009 language recognition system (2010)

This paper presents a description of the MIT Lincoln Laboratory language recognition system submitted to the NIST 2009 Language Recognition Evaluation (LRE). This system consists of a fusion of three core recognizers, two based on spectral similarity and one based on tokenization. The 2009 LRE differed from previous ones in that test data included narrowband segments from worldwide Voice of America broadcasts as well as conventional recorded conversational telephone speech. Results are presented for the 23-language closed-set and open-set detection tasks at the 30, 10, and 3 second durations along with a discussion of the language-pair task. On the 30 second 23-language closed set detection task, the system achieved a 1.64 average error rate.
Oligomerization of ethanol-derived propene and isobutene mixtures to transportation fuels: catalyst and process considerations (2019)

An important activity/selectivity trade-off occurs at increased olefin oligomerization temperatures. Jet-range product decreases and paraffin formation increases at high oligomerization temperatures.
Oligonucleotide Analogues with a Nucleobase-Including Backbone, Part 7, Molecular Dynamics Simulation of a DNA Duplex Containing a 2′-Deoxyadenosine 8-(Hydroxymethyl)-Derived Nucleotide (2001)

The structure and stability of a 14-mer DNA duplex containing a nucleotide analog with a hydroxymethyl substituent at the C(8) of 2′-deoxyadenosine has been investigated by molecular-dynamics simulation. The DNA duplex studied has the sequence 5′-d(CGTAAGCTCGATAG)-3′⋅5′-d(CTATCGA*GCTTACG)-3′, where the O(3′) of the dG6 nucleotide in the second strand is linked through a phosphinato group with the O(10) of the dA 2′-deoxyadenosine-derived nucleotide. Previous experimental results showed that the stability of this duplex in aqueous solution of 0.1M NaCl at pH 7 and room temperature is significantly lower than that of the corresponding unmodified DNA duplex. Comparison of molecular-dynamics trajectories of the unmodified and modified B-DNA duplexes in aqueous solution, at similar conditions than the experiment, shows that the substitution of the dA nucleotide by the dA* nucleotide in the second strand induces stretching of the double helix, which results in opening of the grooves and consequent exposure of the double-helix core to the solvent.
The Role of the High-Density Lipoprotein Receptor SR-BI in the Lipid Metabolism of Endocrine and Other Tissues (2003)

Because cholesterol is a precursor for the synthesis of steroid hormones, steroidogenic tissues have evolved multiple pathways to ensure adequate supplies of cholesterol. These include synthesis, storage as cholesteryl esters, and import from lipoproteins. In addition to endocytosis via members of the low-density lipoprotein receptor superfamily, steroidogenic cells acquire cholesterol from lipoproteins by selective lipid uptake. This pathway, which does not involve lysosomal degradation of the lipoprotein, is mediated by the scavenger receptor class B type I (SR-BI). SR-BI is highly expressed in steroidogenic cells, where its expression is regulated by various trophic hormones, as well as in the liver. Studies of genetically manipulated strains of mice have established that SR-BI plays a key role in regulating lipoprotein metabolism and cholesterol transport to steroidogenic tissues and to the liver for biliary secretion. In addition, analysis of SR-BI-deficient mice has shown that SR-BI expression is important for alpha-tocopherol and nitric oxide metabolism, as well as normal red blood cell maturation and female fertility. These mouse models have also revealed that SR-BI can protect against atherosclerosis. If SR-BI plays similar physiological and pathophysiological roles in humans, it may be an attractive target for therapeutic intervention in cardiovascular and reproductive diseases.