gebhart/patrepeval huggingface dataset:
G402 Numerical Analysis of Vortical Flow Structures in a Centrifugal Compressor Impeller with Vaneless Diffuser (2007)

The flow field in a centrifugal compressor is highly three-dimensional and complicated by the strong secondary flows. In order to improve the performance and operating range, it is indispensable to elucidate the three-dimensional flow phenomena. In this paper, the flow fields in a centrifugal compressor impeller with vaneless diffuser have been investigated by numerical flow analysis. Three-dimensional separated and vortical flow fields were analyzed by Reynolds-averaged Navier-Stokes simulations (RANS) using an unfactored implicit upwind relaxation scheme. As the turbulence model k-ω two-equation model was employed. To elucidate the complicated flow fields, vortex structures were identified by the critical point theory. From numerical analysis results , it was found that the tip leakage vortex breakdown occurred and the leakage vortex of the full-blade interacts with the splitter-blade leading edge at the operating point of maximum pressure rise. This phenomenon causes the large loss and significant impact on the total performance characteristics.
Imaging Multimode Vibrations in High-Frequency Aluminum Nitride Piezoelectric Nanomembrane Resonators (2019)

We report on the first imaging and visualization of the multimode resonant behaviors of aluminum nitride (AlN) piezoelectric nanomembrane resonators, by exploiting a spectromicroscopy technique based on scanning laser interferometry. High-frequency multimode vibrations (up to 33MHz) with quality (Q) factors up to ~8500 are observed in the AlN nanomembranes. Both undriven thermomechanical and coherently excited vibrations of the devices are measured and spatially mapped. Such a multimode AlN device platform with abundant resonant modes, two-dimensional (2D) large capturing surfaces, and efficient all-electrical signal transduction, holds strong promise for enabling ultrasensitive gravimetric detection, mass spectroscopy, and inertial imaging.
A multiyear follow-on study examining safety, immunity, and clinical outcomesfor sargramostim therapy in Parkinson’s disease (2022)

Abstract Safety, biomarker, and motor outcomes in Parkinson’s disease (PD) were evaluated during extended sargramostim (Leukine®, granulocyte-macrophage colony-stimulating factor) therapy. Hematologic, metabolic, regulatory T cell (Treg) numbers and function, motor, and behavioral functions were scored in five PD patients during a 5-day on, 2-day off sargramostim regimen administered at 3 µg/kg/dose over the 33-month study. Adverse events for sargramostim included injection site reactions, increased total white cell counts, and bone pain. Treg numbers and functional improvements were sustained throughout the study. After 24 months on treatment regimen, drug use was discontinued for three months, and followed by an additional six months of treatment. No significant changes in adverse events were discernible after treatment pause or re-initiation; however, UPDRS scores increased during the pause and decreased after initiation of treatment. Taken together, the data affirmed long-term safety, Treg functional stability, and clinical stability of sargramostim in the PD population. Confirmation requiring larger numbers of enrolled patients is planned in a phase II evaluation.
Web-scale pharmacovigilance: listening to signals from the crowd (2013)

Adverse drug events cause substantial morbidity and mortality and are often discovered after a drug comes to market. We hypothesized that Internet users may provide early clues about adverse drug events via their online information-seeking. We conducted a large-scale study of Web search log data gathered during 2010. We pay particular attention to the specific drug pairing of paroxetine and pravastatin, whose interaction was reported to cause hyperglycemia after the time period of the online logs used in the analysis. We also examine sets of drug pairs known to be associated with hyperglycemia and those not associated with hyperglycemia. We find that anonymized signals on drug interactions can be mined from search logs. Compared to analyses of other sources such as electronic health records (EHR), logs are inexpensive to collect and mine. The results demonstrate that logs of the search activities of populations of computer users can contribute to drug safety surveillance.
Quantum dot active regions for extended-wavelength (1.0 μm to 1.3 μm) GaAs-based heterostructure lasers and vertical-cavity surface-emitting lasers (1999)

In this paper we discuss crystal growth, spontaneous emission characteristics and low threshold performance of 1.3 micrometers InGaAs/GaAs quantum dot heterostructure lasers grown using sub-monolayer depositions of In, Ga, and As. Oxide-confinement is effective in obtaining a low threshold current of 1.2 mA and threshold current density of 19 A/cm<SUP>2</SUP> under continuous-wave room-temperature operation. At 4 K a remarkably low threshold current density of 6 A/cm<SUP>2</SUP> is obtained. We also discuss ground state lasing at (lambda) equals 1.07 micrometers of a vertical cavity surface emitting laser in which a stacked and high dot density active region has been incorporated. The high QD density active region is achieved using alternating monolayers of InAs and GaAs. Lasing threshold conditions and gain parameters for a ground state quantum dot vertical cavity laser are also analyzed.
Commentary on ATX-101 (Deoxycholic Acid Injection) for Paradoxical Adipose Hyperplasia Secondary to Cryolipolysis (2017)

David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California Department of Dermatology, University of California, Irvine, Irvine, California Private Practice, Newport Beach, California Human Biology, Health, and Society, College of Human Ecology, Cornell University, Ithaca, New York A.M. Rotunda receives royalty from sales of deoxycholic acid (ATX-101).
Host Immune Status Influences the Development of Attaching and Effacing Lesions in Weaned Pigs (2005)

Attaching and effacing Escherichia coli (AEEC) has been associated with naturally occurring attaching and effacing (A/E) lesions in weaned pigs, and although A/E lesions have been experimentally reproduced in newborn piglets, such lesions have been much more difficult to induce in older conventional pigs. Hence, the aim of this study was to examine the effect of oral administration of dexamethasone on the development of A/E lesions in weaned pigs challenged with a porcine enteropathogenic E. coli (PEPEC) strain and to investigate the involvement of local intestinal cytokine response. Dexamethasone, given orally at a dosage of 3 mg kg of body weight(-1), significantly enhanced both the colonization of the challenge strain and the prevalence of foci of intimately adherent bacteria, resulting in extensive A/E lesions in the ileum, cecum, and colon of challenged pigs. We also confirmed the expression of both intimin and Tir by PEPEC strain ECL1001 in A/E lesions in vivo, which is, to our knowledge, the first report of the involvement of the latter proteins in any AEEC infections in vivo. Moreover, semiquantitative reverse transcription-PCR demonstrated that interleukin 1beta (IL-1beta), IL-6, IL-8, and, to a lesser extent, IL-12p40 are significantly upregulated in the ileum following challenge with strain ECL1001, whereas dexamethasone blocks such upregulation. Taken together, our results strongly suggested that host immune status influences the development of A/E lesions in weaned pigs, and it appears that IL-1beta, IL-6, IL-8, and, to a lesser extent, IL-12p40 are expressed during infection of weaned pigs by PEPEC and may contribute to the natural resistance of the host against PEPEC infection.
Alcohol Use Disorders and Perceived Drinking Norms: Ethnic Differences in Israeli Adults (2012)

This is the first demonstration that drinking norms mediate ethnic differences in AUDs. This work contributes to understanding ethnic group differences in drinking and AUDs, potentially informing etiologic research and public policy aimed at reducing alcohol-related harm.
Resource use and Costs for a Glaucoma Screening Program in Austria: An 8-Year Review.: A Cost-Consequence Analysis Based on the Salzburg-Moorfields Collaborative Glaucoma Study (2006)

Direct costs per visit were considerably higher than those reported in the Netherlands or the United Kingdom. If a health care provider decides to perform a glaucoma screening within this setting, the costs for the detection of a new case are EUR 7250 for definite POAG, EUR 4250 for early POAG, EUR 1450 for POAG suspect, EUR 5600 for OHT, EUR 2100 for glaucoma artefact case, and EUR 156 for a normal case.
Use of High Volumes of Fly Ash to Improve ECC Mechanical Properties and Material Greenness (2007)

Environmental sustainability considerations are taken into account in this report on high-performance fiber-reinforced cementitious composite (HPFRCC) development. Featuring high tensile ductility with high volumes of fly ash (HVFA) replacement of cement (up to 85% by weight), unique HPFRCC members are engineered cementitious composites (ECC). While the material design process sees application of micromechanics in many of its aspects, this study emphasizes how fly ash content alters material microstructure and mechanical properties. While they incorporate high recycled fly ash volumes, HVFA ECCs are shown in experimental results to be able to retain an approximately 2 to 3% long-term tensile ductility. Significantly, there is reduction in both free drying shrinkage and crack width with a fly ash amount increase, though which HVFA ECC structures' long term durability may benefit. That HVFA ECCs' fiber/matrix interface frictional bond increase is responsible for tight crack width is indicated through micromechanics analysis. Use of industrial waste stream material instead of cement reduces environmental impact and achieves more saturated multiple cracking, meaning a robustness improvement is shown in HVFA ECCs.
Impact of cross phase modulation in WDM systems (2002)

We discuss the dynamics of cross phase modulation in optical fibers and study the impact of this phenomenon the performance of WDM systems.
VEGFR3 does not sustain retinal angiogenesis without VEGFR2 (2015)

Angiogenesis, the formation of new blood vessels, is regulated by vascular endothelial growth factors (VEGFs) and their receptors (VEGFRs). VEGFR2 is abundant in the tip cells of angiogenic sprouts, where VEGF/VEGFR2 functions upstream of the delta-like ligand 4 (DLL4)/Notch signal transduction pathway. VEGFR3 is expressed in all endothelia and is indispensable for angiogenesis during early embryonic development. In adults, VEGFR3 is expressed in angiogenic blood vessels and some fenestrated endothelia. VEGFR3 is abundant in endothelial tip cells, where it activates Notch signaling, facilitating the conversion of tip cells to stalk cells during the stabilization of vascular branches. Subsequently, Notch activation suppresses VEGFR3 expression in a negative feedback loop. Here we used conditional deletions and a Notch pathway inhibitor to investigate the cross-talk between VEGFR2, VEGFR3, and Notch in vivo. We show that postnatal angiogenesis requires VEGFR2 signaling also in the absence of Notch or VEGFR3, and that even small amounts of VEGFR2 are able to sustain angiogenesis to some extent. We found that VEGFR2 is required independently of VEGFR3 for endothelial DLL4 up-regulation and angiogenic sprouting, and for VEGFR3 functions in angiogenesis. In contrast, VEGFR2 deletion had no effect, whereas VEGFR3 was essential for postnatal lymphangiogenesis, and even for lymphatic vessel maintenance in adult skin. Knowledge of these interactions and the signaling functions of VEGFRs in blood vessels and lymphatic vessels is essential for the therapeutic manipulation of the vascular system, especially when considering multitargeted antiangiogenic treatments.
Imaging and Antitumoral Effect of a Cyclo-oxygenase 2-specific Replicative Adenovirus for Small Metastatic Gastric Cancer Lesions. (2015)

Cox2 CRAds with 5/3 chimeric-fiber modification, therefore, appear to be a promising imaging and therapeutic tools for peritoneal dissemination of gastric cancer.
Performance Evaluation of ATSC 3.0 Mobile Service with LDM/TDM Under TU-6 Channel (2018)

This paper presents performance comparison between layered division multiplexing (LDM) and time division multiplexing (TDM) based mobile services in the Advanced Television System Committee (ATSC) 3.0 standard. The comparison has been performed through extensive computer simulations, leveraging full-chain simulator entirely compliant with A/322. The simulation results demonstrate that LDM can significantly lower the signal-to-noise ratio (SNR) requirement compared to TDM in a given mobile scenario while maintaining the same (or analogous possible) data rate. For instance, LDM based mobile service is 6.1 dB more robust than TDM based service at a velocity of 100 km/h. In addition, even though LD M uses larger FFT size than TDM (16k-FFT for LDM and 8k-FFT for TDM), it is verified that LDM based mobile service is fully feasible under high speed condition.
Superconducting Properties of K3C60 and Rb3C60 Single Crystals in High Fields (1994)

Abstract The critical superconducting temperature of Rb3C60 and K3C60 single crystals was measured in static magnetic fields up to 23 T by a resistive method. It is shown that within the experimental accuracy no enhancement of the critical field HC2 is found at low temperature. The HC2(T) follows the Werthamer, Helfand and Hohenberg theory quite well.
Investigation of Channel Properties for 28 GHz Band in Urban Street Microcell Environments (2018)

In Japan, field trials on the fifth generation mobile communications system (5G) were started in order to create a new market by actualizing 5G. The 28 GHz band is the most promising candidate for commercial 5G systems. When designing the service area, site-specific channel properties in urban areas are required. Therefore, in this paper, we investigate site-specific channel properties for the 28 GHz band in an urban street microcell environments and clarify that the paths affect the channel properties.
Flexible and wearable acoustic wave technologies (2023)

Flexible and wearable acoustic wave technology has recently attracted tremendous attention due to their wide-range applications in wearable electronics, sensing, acoustofluidics, and lab-on-a-chip, attributed to its advantages such as low power consumption, small size, easy fabrication, and passive/wireless capabilities. Great effort has recently been made in technology development, fabrication, and characterization of rationally designed structures for next-generation acoustic wave based flexible electronics. Herein, advances in fundamental principles, design, fabrication, and applications of flexible and wearable acoustic wave devices are reviewed. Challenges in material selections (including both flexible substrate and piezoelectric film) and structural designs for high-performance flexible and wearable acoustic wave devices are discussed. Recent advances in fabrication strategies, wave mode theory, working mechanisms, bending behavior, and performance/evaluation are reviewed. Key applications in wearable and flexible sensors and acoustofluidics, as well as lab-on-a-chip systems, are discussed. Finally, major challenges and future perspectives in this field are highlighted.
Silicon Promotes Growth of Brassica napus L. and Delays Leaf Senescence Induced by Nitrogen Starvation (2018)

Silicon (Si) is the second most abundant element in soil and has several beneficial effects, especially in plants subjected to stress conditions. However, the effect of Si in preventing nitrogen (N) starvation in plants is poorly documented. The aim of this work was to study the effect of a short Si supply duration (7 days) on growth, N uptake, photosynthetic activity, and leaf senescence progression in rapeseed subjected (or not) to N starvation. Our results showed that after 1 week of Si supply, Si improves biomass and increases N uptake and root expression of a nitrate transporter gene. After 12 days of N starvation, compared to -Si plants, mature leaf from +Si plants showed a high chlorophyll content, a maintain of net photosynthetic activity, a decrease of oxidative stress markers [hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) and malondialdehyde (MDA)] and a significant delay in senescence. When N-deprived plants were resupplied with N, a greening again associated with an increase of photosynthetic activity was observed in mature leaves of plants pretreated with Si. Moreover, during the duration of N resupply, an increase of N uptake and nitrate transporter gene expression were observed in plants pretreated with Si. In conclusion, this study has shown a beneficial role of Si to alleviate damage associated with N starvation and more especially its role in delaying of leaf senescence.
Characterization of Human and Rat Intestinal Trefoil Factor Produced in Yeast (1995)

Intestinal trefoil factor (ITF) from human (hITF) and rat (rITF) have been produced in Saccharomyces cerevisiae. The DNA encoding the two peptides were cloned by polymerase chain reactions (PCR) from a human normal colon library and a rat small intestinal epithelial cell library. Recombinant plasmids were constructed to encode a fusion protein consisting of a hybrid leader sequence and the rat and human ITF sequences, respectively. The leader sequence used serves to direct the fusion protein into the secretory (and processing) pathway of the cell. The secreted recombinant hITF was found in a monomer and a dimer form, whereas the rITF was only secreted as a dimer. The secreted peptides were purified by a combination of ionic exchange chromatography and preparative HPLC. From 8 L of yeast fermentation broth, 256 mg of hITF (monomer) and 133 mg of hITF (dimer) were isolated, and from 8.7 L of fermentation broth, 236 mg of rITF (dimer) was isolated. The structure of hITF (monomer), hITF (dimer), and rITF (dimer) was determined by amino acid analyses, peptide mapping, sequence analyses, and electrospray mass spectrometry analyses. In hITF (monomer) six of the seven cysteines are disulfide-linked to form 3 disulfide bridges. Mass analysis indicated that the last cysteine residue (Cys-57) did not exist as free (-SH) cysteine, but have reacted with cysteine to form an S-S linked cystine. Sequence and mass spectrometry analyses as well as peptide mapping showed that the dimer form of both hITF and rITF is mediated by a disulfide bridge between Cys-57 residues of two monomers.
The n-dimensional key equation and a decoding application (1994)

The author introduce the n-dimensional key equation, which exhibits the error-locator polynomial of an n-dimensional cyclic code as a product of n univariate polynomials and the error-evaluator polynomial as an n-variable polynomial. They then reinterpret these polynomials in the context of linear recurring sequences. In particular, they reduce the decoding problem to successive application of the Berlekamp-Massey algorithm. With this new method, they are able to decode (up to half their minimum distance) many codes in a table of 2-D cyclic codes due to Jensen (1985).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Measurements of the $$W$$ W production cross sections in association with jets with the ATLAS detector (2015)

This paper presents cross sections for the production of a [Formula: see text] boson in association with jets, measured in proton-proton collisions at [Formula: see text] with the ATLAS experiment at the large hadron collider. With an integrated luminosity of [Formula: see text], this data set allows for an exploration of a large kinematic range, including jet production up to a transverse momentum of [Formula: see text] and multiplicities up to seven associated jets. The production cross sections for [Formula: see text] bosons are measured in both the electron and muon decay channels. Differential cross sections for many observables are also presented including measurements of the jet observables such as the rapidities and the transverse momenta as well as measurements of event observables such as the scalar sums of the transverse momenta of the jets. The measurements are compared to numerous QCD predictions including next-to-leading-order perturbative calculations, resummation calculations and Monte Carlo generators.
Pseudomonas Alcaligenes Endocarditis (1983)

Pseudomonas alcaligenes is a common soil and water inhabitant that has rarely been proven a human pathogen. We describe a fatal case of Pseudomonas alcaligenes endocarditis. The need for accurate identification of unusual organisms isolated in a clinical setting are discussed.
Spatio-temporal imaging of light transport in scattering media using white light illumination(Conference Presentation) (2016)

We recently showed how the correlations of a broadband and incoherent wave-field can directly yield the time-dependent Green's functions between scatterers of a complex medium [Badon et al., Phys. Rev. Lett., 2015]. In this study, we apply this approach to the imaging of optical transport properties in complex media. A parallel measurement of millions of Green's functions at the surface of several strongly scattering samples (ZnO, TiO2, Teflon tape) is performed. A statistical analysis of this Green’s matrix allows to investigate locally the spatio-temporal evolution of the diffusive halo within the scattering sample. An image of diffusion tensor is then obtained. It allows to map quantitatively the local concentration of scatterers and their anisotropy within the scattering medium. The next step of this work is to test this approach on biological tissues and illustrate how it can provide an elegant and powerful alternative to diffuse optical imaging techniques.
Melt-processing, moisture-resistance and strength retention properties of supercritical CO2-processed thermoplastic starch resins (2018)

This paper represents the first report of thermoplastic starch (scCO 2 TPS) and glutaraldehyde (GA) modified TPS resins (scCO 2 TPS 100 GA x ), gelatinized and/or modified with the aid of supercritical carbon dioxide (scCO 2 ). The melt flow rate, initial and retention values of tensile strength ( f ) of TPS and GA-modified TPS prepared using scCO 2 fluid were considerably higher than those of TPS and TPS 100 GA x materials prepared in the conventional way. After conditioning at 20 C/50% RH for 56 days, the f of properly prepared scCO 2 TPS 100 GA 0.1 still remained at 17.5 MPa, which is around 3.5 times of that of the corresponding conditioned TPS 100 GA 0.1 . The moisture contents of conditioned scCO 2 TPS and scCO 2 TPS 100 GA x were considerably lower than those of the corresponding TPS and TPS 100 GA x aged for the same amounts of time. Conditioned scCO 2 TPS and scCO 2 TPS 100 GA x exhibited only V h -type crystals with melting temperatures ~20 C lower than those of corresponding conditioned TPS and TPS 100 GA x . In comparison to TPS and TPS 100 GA x , more dissociated amylopectin chains with loosely hydrogen-bonded -OH groups and significantly less retrogradation was found for conditioned scCO 2 TPS and scCO 2 TPS 100 GA x .