gebhart/patrepeval huggingface dataset:
RPM — Residual Potential Mapping; A New Approach to Mise‐a‐la‐masse (2004)

PreviousNext No AccessSymposium on the Application of Geophysics to Engineering and Environmental Problems 2004RPM — Residual Potential Mapping; A New Approach to Mise‐a‐la‐masseAuthors: Christopher A. BaldygaJames B. FinkChristopher A. BaldygahydroGEOPHYSICS, Inc., Tucson, Arizona and James B. FinkhydroGEOPHYSICS, Inc. ‐ Tucson, Arizonahttps://doi.org/10.4133/1.2923400 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Abstract Introductory paragraph for this paper is available only in the PDF and GZipped PS filesPermalink: https://doi.org/10.4133/1.2923400FiguresReferencesRelatedDetails Symposium on the Application of Geophysics to Engineering and Environmental Problems 2004ISSN (online):1554-8015Copyright: 2004 Pages: 1823 publication data© 2004 Copyright © 2004 The Environmental and Engineering Geophysical SocietyPublisher:Environmental & Engineering Geophysical Society HistoryPublished: 30 Sep 2008 CITATION INFORMATION Christopher A. Baldyga and James B. Fink, (2004), "RPM — Residual Potential Mapping; A New Approach to Mise‐a‐la‐masse," Symposium on the Application of Geophysics to Engineering and Environmental Problems Proceedings : 851-855. https://doi.org/10.4133/1.2923400 Plain-Language Summary PDF DownloadLoading ...
ChemInform Abstract: ADDITION VON ORGANOMAGNESIUM‐VERBINDUNGEN AN NICHT AKTIVIERTE C=C‐DOPPELBINDUNGEN 4. MITT. BENZYLMAGNESIUMCHLORID UND OLEFINE (1973)

Abstract Benzylmagnesiumchlorid (I) reagiert mit Äthylen (II) in n‐Pentan als Lösungsmittel bei 100°C zu Addukten, aus denen bei der Hydrolyse die Alkylbenzole (III)‐(V) erhalten werden.
Lymphocyte Phenotype and Function Changes in Burn Patients After Intravenous IgG Therapy (1988)

The effects of prophylactic administration of intravenous IgG on immune-cell phenotype and function in burn patients were compared with those of patients receiving standard therapy. Intravenous IgG infusions were given twice weekly for three weeks postburn or until wound closure. Intravenous IgG had no effect on the proportion of total T-lymphocytes, T-helper lymphocytes, or T-suppressor lymphocytes, but the proportion of B-lymphocytes decreased 40% in treated patient samples. Lymphocytes from treated patients incorporated less thymidine when stimulated with concanavalin A or pokeweed mitogen, but not with phytohemagglutinin. The amount of IgM secreted by pokeweed mitogen-stimulated cultures from treated patients increased by 24%, while the amount of IgG remained constant. The changes in beta-lymphocyte number and functional response may have been induced by the increased serum IgG levels in the intravenous IgG-treated patients.
Effects of weight loss and long-term weight maintenance with diets varying in protein and glycemic index on circulating pro-neurotensin in the Diet, Obesity, and Genes (DiOGenes) Study: a randomized, controlled trial (2016)

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
Cell envelope mutants of Pseudomonas putida : physiological characterization and analysis of their ability to survive in soil (1999)

To generate mutants with altered lipopolysaccharides (LPS) of the wild-type Pseudomonas putida KT2442, we used the mini-Tn5luxAB-Km transposon. A mutant was found among luminescent colonies and selected as a negative clone in enzyme-linked immunosorbent assay (ELISA) with monoclonal antibody (mAb) 7.3B, which recognizes the O-antigen of P. putida LPS. The DNA region of the LPS mutant interrupted by the minitransposon insertion was cloned and sequenced. Comparison of the deduced amino acid sequence with protein sequence databases showed similarity to the O-antigen polymerase (Wzy) of Salmonella enterica (muenchen). The wild-type gene was rescued by polymerase chain reaction (PCR), cloned into a broad-host-range plasmid and used to carry out complementation assays. The cloned gene was able to restore the wild-type phenotype of the P. putida wzy mutant. We constructed an isogenic mutant of the luminescent wzy mutant to which an oprL mutation was transferred by homologous recombination with an oprL::xylE cassette. The wzy mutants of P. putida were more sensitive to SDS, deoxycholate and EDTA than the corresponding parental strains. We analysed the ability of wzy, oprL and wzy oprL mutants of P. putida to colonize soil. In comparison with the wild-type strain, the ability of single mutants to colonize soil decreased; this characteristic was more evident for the double mutant, especially at high temperatures.
Modeling Flood Prevention Designs for Southwest Regina (2011)

The Albert Park neighbourhood of Regina has experienced multiple flood events in the last 40 years. The existing drainage system and several alternative designs were modelled in EPA SWMM, a stormwater drainage software program, to aid in designing a system that will reduce future flooding. Flooding in the current system was compared to flooding in each alternative design. The study results in an alternative design that provides the most effective flood prevention.
Nonpositive Hopfield Networks in Error Correcting Coding Applications (1993)

We consider a class of symmetric Hopfield Networks, with nonpositive synapses and zero thresholds and address a variety of design and analysis issues conected with Unidirectional Error Correcting Coding applications of this class. We show that this class is naturally suited to work in a unidirectional error environment We give a necessary and sufficient condition for a set of vectors to be storable in a Nonpositive Network. We propose a simple word storage algorithm, which is amenable to on line implementation, and guarantees storage of all storage compatible words. We show that the storage algorithm creates a maximally fault tolerant network which is free from spurious stationary points, whenever that freedom is possible. We also give a word forgetting algorithm; a tight, deterministic bound on the storage capacity, and give conditions under which the network created by our storage scheme tolerates a given number of arbitrary physical faults.
To-Syn-Fuel: Turning Sewage Sludge into Fuels and Hydrogen (2018)

The To-Syn-Fuel project aims to demonstrate a sustainable process able to transform waste biomass such as sewage sludge into renewable liquid fuels. The Thermo-Catalytic Reforming TCR®, which is a technology developed by Fraunhofer UMSICHT, will be implemented in a new process integrated with hydrodeoxygenation (HDO) and pressure swing adsorption (PSA) technologies to convert a wide range of residual biomass into three main products: H2-rich synthesis gas, biochar and a liquid bio-oil that can be upgraded to green fuels being ready to be used directly in automotive internal combustion engines, as they fulfil EN fuel standards. To-Syn-Fuel is designed to set the benchmark for future sustainable development within Europe, by providing a valuable example of sustainable synthetic fuels and green hydrogen production to the rest of the world, while successfully addressing energy, environmental, economic and social needs.
Carcinoma of the nasopharynx: Analysis of treatment results in 167 consecutively admitted patients (1992)

Radiotherapy with curative intent was administered to 159 of 167 consecutively admitted patients with nasopharyngeal carcinoma. The classification (UICC 1982) gave the staging: stage I 8%, stage II 2%, stage III 28%, and stage IV 61%. The actuarial local tumor control was 54% and correlated to the T-classification. Primary control of neck nodes was 67% but was not correlated to the N-classes. Distant failure occurred in 20% of the patients; this was correlated to the N-classification. The 10-year actuarially corrected survival rate was 37% (stage I+II 60%, stage III 49%, stage IV 27%). Late reactions were seen in 69%, and most patients had mild to moderate xerostomia. Men with high hemoglobin had a better prognosis than men with values in the lower part of the normal range. It is concluded that primary control in the T- and N-positions is the parameter most crucial to success.
Oxidative Synthesis of Isoxazoline-N-oxide from Optically Active Nitro Alcohols (2016)

9c S2ORTEP chart for compound 7b S16ORTEP chart for compound 8a S16
Glutathione peroxidase 4 and vitamin E control reticulocyte maturation, stress erythropoiesis and iron homeostasis (2019)

Glutathione peroxidase 4 (GPX4) is unique as it is the only enzyme that can prevent detrimental lipid peroxidation <i>in vivo</i> by reducing lipid peroxides to the respective alcohols thereby stabilizing oxidation products of unsaturated fatty acids. During reticulocyte maturation, lipid peroxidation mediated by 15-lipoxygenase in humans and rabbits and by 12/15-lipoxygenase (ALOX15) in mice was considered the initiating event for the elimination of mitochondria but is now known to occur through mitophagy. Yet, genetic ablation of the <i>Alox15</i> gene in mice failed to provide evidence for this hypothesis. We designed a different genetic approach to tackle this open conundrum. Since either other lipoxygenases or non-enzymatic autooxidative mechanisms may compensate for the loss of <i>Alox15</i>, we asked whether ablation of <i>Gpx4</i> in the hematopoietic system would result in the perturbation of reticulocyte maturation. Quantitative assessment of erythropoiesis indices in the blood, bone marrow (BM) and spleen of chimeric mice with <i>Gpx4</i> ablated in hematopoietic cells revealed anemia with an increase in the fraction of erythroid precursor cells and reticulocytes. Additional dietary vitamin E depletion strongly aggravated the anemic phenotype. Despite strong extramedullary erythropoiesis reticulocytes failed to mature and accumulated large autophagosomes with engulfed mitochondria. <i>Gpx4</i>-deficiency in hematopoietic cells led to systemic hepatic iron overload and simultaneous severe iron demand in the erythroid system. Despite extremely high erythropoietin and erythroferrone levels in the plasma, hepcidin expression remained unchanged. Conclusively, perturbed reticulocyte maturation in response to <i>Gpx4</i> loss in hematopoietic cells thus causes ineffective erythropoiesis, a phenotype partially masked by dietary vitamin E supplementation.
TU‐A‐BRC‐05: Imaging to Monitor the Efficacy of Novel Molecular Targeted Radiation Protecting Drugs (2011)

Purpose: This research addresses apoptosis within stem cells and necrosis as two common mechanisms of radiation induced tissue injury. Inhibitors of enzyme GSK3&amp;#946; markedly attenuate radiation induced apoptosis in normal tissues but not in cancer. These drugs prevented radiation induced injury in brain, intestine, bone marrow and skin. Here we develop noninvasive imaging as a means to monitor radioprotection by GSK3 inhibitors. Methods: Specific inhibitors of GSK3, SB2 and SB4, were administered to mice by IP injection prior to irradiation. Single‐treatment Gamma Knife doses of 15–60Gy were given to the 50% isodose volume (33.5mm3) in one mouse brain hemisphere. T2‐weighted, microMRI of the brain was performed weekly. Whole abdominal doses of 7–8Gy were used to treat intestine. F18‐labeled apoptosis radiotracer was manufactured in the radiochemistry laboratory and was injected by tail vein in mice at 24 hours after irradiation. MicroPET imaging was performed to monitor uptake of the apoptosis detector following irradiation. Results: Radiation induced apoptosis in the brain and intestine occurred after 24 hours in a dose dependent manner with doses as low as 2Gy. Brain necrosis was compared histologically with imaging following 15‐60Gy and was first detected 3–7 weeks after irradiation. GSK3 inhibition prevented radiation induced apoptosis and preserved organ function in irradiated mice. MRI detected brain necrosis in mice treated with Gamma Knife. The apoptosis radiotracer has a short half life which is sufficient because apoptosis is transiently detected at 24 hours after irradiation. Renal excretion of the radiotracer allows imaging of radiation induced apoptosis in intestinal crypts after abdominal irradiation. Conclusions: Radioprotection of the brain and intestine by GSK3&amp;#946; inhibitors can be monitored by MRI and PET imaging. Radiotracers with a high sensitivity for apoptosis are needed to monitor apoptosis. These imaging modalities are needed for the planned clinical trials of GSK3 inhibitors as radioprotectors.
An improved synthesis of diammonium acetyl phosphate (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn improved synthesis of diammonium acetyl phosphateJerome M. Lewis, Sharon L. Haynie, and George M. WhitesidesCite this: J. Org. Chem. 1979, 44, 5, 864–865Publication Date (Print):March 1, 1979Publication History Published online1 May 2002Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/jo01319a048https://doi.org/10.1021/jo01319a048research-articleACS PublicationsRequest reuse permissionsArticle Views176Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Whole exome sequencing characterization of individuals presenting extreme phenotypes of high and low risk of developing tobacco-induced lung adenocarcinoma (2021)

We describe genetic variants associated with extreme phenotypes of high and low risk for the development of tobacco-induced lung adenocarcinoma. Our results and our strategy may help to identify high-risk subjects and to develop new therapeutic approaches.
Measurement-based modeling for data centers (2010)

We present a heat transfer model for data centers where real-time measurement data is used to reduce the complexity in the specifications of the model. As this modeling approach obtains its input directly from real-time measurements (in the form of boundary data), it is suitable for operational and real-time usage. Although the model is simpler than those based on the use of the Navier-Stokes equations for fluid flow, numerical experiments suggest that it can nevertheless provide useful information for use in data center energy management.
Synthesis of Selectively Protected Chitobiose and Chitotriose Derivatives from one Precursor. Versatile Building Blocks for Oligosaccharide Synthesis (1994)

Abstract The inner core region of cell surface N-glycoproteins consists of a chitobiose substructure2, containing β-(1,4)-linked disaccharides of glucosamine. Such carbohydrate structures are also found as repeating units of the bacterial cell wall peptidoglycan3 and in novel tetra- and pentasaccharide plant hormones, which are nodulation factors on legume roots.4 Since the first synthesis of a chitobiose derivative in 1966 by Paulsen,5 approaches to these compounds have relied mainly on the oxazoline method.6 The coupling reactions of aminosugar chlorides,7 bromides,8 acetates9 and trichloroacetimidates10 to suitable glycosyl acceptors have also been described. Most of these syntheses11 require two completely different coupling partners; only in very few examples could the glycosyl donor and acceptor be obtained from the same starting material.12 During our investigations into the stereocontrolled synthesis of glucosamine oligosaccharides, we required an economical synthetic route to protected derivatives of chitotriose. For the purpose of easy oligomerization, the anomeric protecting group of every building block had to be exchangeable selectively with the activating group for the next glycosylation. In this paper, we report an efficient approach to chitobiose and chitotriose from a single precursor. Furthermore, the hydroxyl groups at C-1, C-3, C-4, C-6 of these oligosaccharides are differentially protected. This protecting group scenario allows a specific access to any of these functionalities by regioselective deblocking. The N-phthalimide group was chosen out of several possible amino protecting groups to ensure β-selectivity and simultaneous activation in the coupling.13
Progress towards a glycoconjugate vaccine against Group A Streptococcus (2023)

The Group A Carbohydrate (GAC) is a defining feature of Group A Streptococcus (Strep A) or Streptococcus pyogenes. It is a conserved and simple polysaccharide, comprising a rhamnose backbone and GlcNAc side chains, further decorated with glycerol phosphate on approximately 40% GlcNAc residues. Its conservation, surface exposure and antigenicity have made it an interesting focus on Strep A vaccine design. Glycoconjugates containing this conserved carbohydrate should be a key approach towards the successful mission to build a universal Strep A vaccine candidate. In this review, a brief introduction to GAC, the main carbohydrate component of Strep A bacteria, and a variety of published carrier proteins and conjugation technologies are discussed. Components and technologies should be chosen carefully for building affordable Strep A vaccine candidates, particularly for low- and middle-income countries (LMICs). Towards this, novel technologies are discussed, such as the prospective use of bioconjugation with PglB for rhamnose polymer conjugation and generalised modules for membrane antigens (GMMA), particularly as low-cost solutions to vaccine production. Rational design of "double-hit" conjugates encompassing species specific glycan and protein components would be beneficial and production of a conserved vaccine to target Strep A colonisation without invoking an autoimmune response would be ideal.
Domain wall dynamics in two-dimensional van der Waals ferromagnets (2021)

Domain wall motion is in the core of many information technologies ranging from storage [Beach et al., J. Magn. Magn. Mater. 320, 1272–1281 (2008)], processing [Tatara et al., Phys. Rep. 468, 213–301 (2008)], and sensing [Ralph and Stiles, J. Magn. Magn. Mater. 320, 1190–1216 (2008)] up to novel racetrack memory architectures [Parkin et al., Science 320, 190–194 (2008)]. The finding of magnetism in two-dimensional (2D) van der Waals (vdW) materials [Huang et al., Nature 546, 270 (2017); Gong et al., Nature 546, 265–269 (2017); Guguchia et al., Sci. Adv. 4, eaat3672 (2018); Klein et al., Science 360, 1218–1222 (2018)] has offered a new frontier for the exploration and understanding of domain walls at the limit of few atom-thick layers. However, to use 2D vdW magnets for building spintronics nanodevices such as domain-wall based logic [Allwood et al., Science 309, 1688–1692 (2005); Luo et al., Nature 579, 214–218 (2020); Xu et al., Nat. Nanotechnol. 3, 97–100 (2008)], it is required to gain control of their domain wall dynamics by external driving forces such as spin-polarized currents or magnetic fields, which have so far been elusive. Here, we show that electric currents as well as magnetic fields can efficiently move domain walls in the recently discovered 2D vdW magnets CrI3 and CrBr3 at low temperatures and robust down to monolayer. We realize field- and current-driven domain wall motion with velocities up to 1020 m s−1, which are comparable to the state-of-the-art materials for domain-wall based applications [Yang et al., Nat. Nanotechnol. 10, 221–226 (2015); Woo et al., Nat. Mater. 15, 501–506 (2016); Vélez et al., Nat. Commun. 10, 4750 (2019); Siddiqui et al., Phys. Rev. Lett. 121, 057701 (2018); Ryu et al., Nat. Nanotechnol. 8, 527–533 (2013)]. Domain walls keep their coherence driven by the spin-transfer torque induced by the current and magnetic fields up to large values of about 12×109 A cm−2 and 5 T, respectively. For larger magnitudes of current or field, a transition to a hydrodynamic spin-liquid regime is observed with the emission of a periodic train of spin-wave solitons with modulational instability [Rabinovich and Trubetskov, Oscillations and Waves: In Linear and Nonlinear Systems, Mathematics and its Applications (Springer Netherlands, 2011)]. The emitted waveform achieves terahertz (THz) frequency in a wide range of fields and current densities, which opens up perspectives for reconfigurable magnonic devices. Moreover, we found that these spin-waves can transport spin angular momentum through the layers over distances as long as 10 μm without losses for the transport of spin information. Our results push the boundary of what is currently known about the dynamics of domain walls in 2D vdW ferromagnets and unveil strategies to design ultrathin, high-speed, and high-frequency spintronic devices.
Dual-mode RF receiver front-end using a 0.25-/spl mu/m 60-GHz f/sub T/ SiGe:C BiCMOS7RF technology (2004)

This paper presents a dual-mode RF receiver front-end consisting of a LNA, an active single-ended-to-differential converter and a downconversion mixer. It uses a high performance 0.25-/spl mu/m 60-GHz f/sub T/ SiGe:C BiCMOS7RF integration technology from STMicroelectronics. The proposed RF receiver front-end (RFFE) is targeted to GSM1800 (1805-1880MHz) and WCDMA-FDD (2110-2170MHz) systems. The main motivation of this work is to share as many elements as possible in both modes avoiding conventional parallel receiver chains, which is not a cost-efficient solution. The overall RFFE achievable gain is around 40dB in both modes. The overall front-end noise figure (Friis formula) is less than 1.3dB for GSM1800 and 1.6dB for WCDMA mode. These performances fulfil the systems requirements. The complete RFFE circuit consumes 18 mW in both operation modes at 2.5 V supply voltage.
The Reaction Mass Pendulum (RMP) Model for Humanoid Robot Gait and Balance Control (2009)

The &eaction -ass /endulum (&-
Kinetic Tetrazolium Microtiter Assay (1993)

Kinetic tetrazolium microtiter assay (KTMA) involves use of tetrazolium salts and Triton X-100 (or equivalent), nontoxic, in vitro color developer solubilizing colored metabolite formazan without injuring or killing metabolizing cells. Provides for continuous measurement of metabolism and makes possible to determine rate of action of antimicrobial agent in real time as well as determines effective inhibitory concentrations. Used to monitor growth after addition of stimulatory compounds. Provides for kinetic determination of efficacy of biocide, greatly increasing reliability and precision of results. Also used to determine relative effectiveness of antimicrobial agent as function of time. Capability of generating results on day of test extremely important in treatment of water and waste, disinfection of hospital rooms, and in pharmaceutical, agricultural, and food-processing industries. Assay also used in many aspects of cell biology.