gebhart/patrepeval huggingface dataset:
El recurso de casación contra las resoluciones del Tribunal de Cuentas en materia de responsabilidad contable: un repaso de la jurisprudencia reciente (2015)

espanolEn este trabajo, el autor, una vez expuestas las vias de control a que estan sujetos los actos, disposiciones y resoluciones jurisdiccionales del Tribunal de Cuentas, especialmente a traves del recurso de casacion ante el Tribunal Supremo, examina los pronunciamientos mas desta- cados y recientes de este ultimo en materia de responsabilidad conta- ble. Entre otros aspectos se hace referencia al concepto de responsabi- lidad contable y sus elementos caracterizadores y a la funcion de enjuiciamiento contable del Tribunal de Cuentas como una actividad de naturaleza jurisdiccional. De la mano de la jurisprudencia del Tri- bunal Supremo, se analizan a continuacion otras cuestiones tales como el ambito subjetivo de la responsabilidad contable; la diferencia entre los supuestos de responsabilidad contable por alcance y otras infraccio- nes contables; la independencia de la responsabilidad contable respec- to de la responsabilidad penal y, en fin, la cuestion relativa a cuando sera de apreciar validamente un hecho interruptor de la prescripcion de las responsabilidades contables EnglishIn this paper, the author, once further explained the ways of controlling the Spanish National Court of Auditors acts, provisions and judicial decisions -specially through the appeal in cassation to the Supreme Court-, reviews the most prominent and re- cent judgments of this last in the area of accounting responsibility. Among other issues, particular reference is made to the accounting responsibility concept and its characteristics features, and also to the National Court of Auditors function of ac- counting prosecution as a jurisdictional nature activity. Following the Spanish Su- preme Court’s jurisprudence, the study analyses other questions such as the account- ing responsibility subjective scope; the difference between accounting responsibility and other accounting law breaches; the independence of accounting and criminal responsibility and, finally, under what assumptions can validly be appreciated the interruption of the prescription period concerning accounting responsibility
Synthesis, Structure Elucidation, in Vitro Biological Activity, Toxicity, and Caco-2 Cell Permeability of Lipophilic Analogues of α-Conotoxin MII (2003)

The alpha-conotoxin MII is a two disulfide bridge containing, 16 amino acid long peptide toxin isolated from the marine snail Conus magus. This toxin has been found to be a highly selective and potent inhibitor of neuronal nicotinic acetylcholine receptors (nAChRs) of the subtype alpha3beta2. To improve the bioavailability of this peptide, two lipidic analogues of MII have been synthesized, the first by coupling 2-amino-d,l-dodecanoic acid (Laa) to the N terminus (LaaMII) and the second by replacing Asn5 in the MII sequence with this lipoamino acid (5LaaMII). Both lipidic linear peptides were then oxidized under standard conditions. (1)H NMR shift analysis of these peptides and comparison with the native MII peptide showed that the tertiary structure of the N-conjugated analogue, LaaMII, was consistent with that of the native conotoxin, whereas the 5LaaMII analogue formed the correct disulfide bridges but failed to adopt the native helical tertiary structure. The N terminus conjugate was also found to inhibit nAChRs of the subtype alpha3beta2 with equal potency to the parent peptide, whereas the 5LaaMII analogue showed no inhibitory activity. The active LaaMII analogue was found to exhibit significantly improved permeability across Caco-2 cell monolayers compared to the native MII, and both peptides showed negligible toxicity.
Evaluation of Sustainable P4MCL/PLLA Block Copolymers as PVC Replacement in Medical Plastics (2022)

Abstract Aliphatic polyesters are potential sustainable alternatives to PVC for use in medical devices, such as IV bags. Our candidate replacement of PVC-based IV bags use P4MCL, a sustainable polymer with demonstrated uses in mechanically robust materials. The goal of our project was to compare the mechanical and biocompatibility characteristics of P4MCL/PLLA star block copolymer TPEs with commercial PVC-based IV bags. P4MCL/PLLA TPEs were synthesized according to previously reported methods. Uniaxial tensile testing was conducted pre- and post-autoclave. Impact and tear resistance testing was performed on non-autoclaved specimens according to ASTM standards. Cytotoxicity was examined using NIH 3T3 Fibroblasts with an AlamarBlue assay. A student’s t-test was used to compare results with statistical significance of P &amp;lt; 0.05. PVC tended to be stiffer but P4MCL/PLLA was more extensible. The tensile properties for the P4MCL-based material did not change after autoclaving. When compared to PVC-based IV bags, the P4MCL/PLLA TPE demonstrated a lower peak force and average force but a greater elongation at break and total absorbed energy (P&amp;lt;0.05). P4MCL/PLLA, unlike PVC-based materials with DEHP plasticizer, was non-cytotoxic. In summary, P4MCL/PLLA has desirable mechanical and biocompatibility advantages compared to PVC making the material a potential sustainable alternative for medical grade plastics.
Enantioselective Intramolecular Cyclopropanations of Allylic and Homoallylic Diazoacetates and Diazoacetamides Using Chiral Dirhodium(II) Carboxamide Catalysts (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEnantioselective Intramolecular Cyclopropanations of Allylic and Homoallylic Diazoacetates and Diazoacetamides Using Chiral Dirhodium(II) Carboxamide CatalystsMichael P. Doyle, Richard E. Austin, A. Scott Bailey, Michael P. Dwyer, Alexey B. Dyatkin, Alexey V. Kalinin, Michelle M. Y. Kwan, Spiros Liras, Christopher J. Oalmann, and Cite this: J. Am. Chem. Soc. 1995, 117, 21, 5763–5775Publication Date (Print):May 1, 1995Publication History Published online1 May 2002Published inissue 1 May 1995https://pubs.acs.org/doi/10.1021/ja00126a016https://doi.org/10.1021/ja00126a016research-articleACS PublicationsRequest reuse permissionsArticle Views2903Altmetric-Citations198LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (3)»Supporting Information Supporting Information Get e-Alerts
Conformal SDE doping for FinFETs using an arsenic-doped Sol-Gel Coating (SGC) and Flash Lamp Annealing (FLA) (2017)

We demonstrated the formation of ultra-shallow n+/p junctions in Si using an arsenic-doped Sol-Gel Coating (SGC) (Tokyo Ohka Kogyo Co., Ltd.) [1] and Flash Lamp Annealing (FLA). A high arsenic dopant concentration of 1.2×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">20</sup> atoms/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> (Xj=9.0 nm, Rs= 1203 ohms/sq.) with a good junction profile (2.2 nm/decade) was realized with 1.4 ms FLA. These results indicate that this technique can be used for conformal doping of the Source/Drain Extensions (SDE) in sub-10 nm FinFETs fabricated using advanced 3D device engineering.
Impaired basal glucose effectiveness but unaltered fasting glucose release and gluconeogenesis during short-term hypercortisolemia in healthy subjects (2004)

Excess cortisol has been demonstrated to impair hepatic and extrahepatic insulin action. To determine whether glucose effectiveness and, in terms of endogenous glucose release (EGR), gluconeogenesis, also are altered by hypercortisolemia, eight healthy subjects were studied after overnight infusion with hydrocortisone or saline. Glucose effectiveness was assessed by a combined somatostatin and insulin infusion protocol to maintain insulin concentration at basal level in the presence of prandial glucose infusions. Despite elevated insulin concentrations (P < 0.05), hypercortisolemia resulted in higher glucose (P < 0.05) and free fatty acid concentrations (P < 0.05). Furthermore, basal insulin concentrations were higher during hydrocortisone than during saline infusion (P < 0.01), indicating the presence of steroid-induced insulin resistance. Postabsorptive glucose production (P = 0.64) and the fractional contribution of gluconeogenesis to EGR (P = 0.33) did not differ on the two study days. During the prandial glucose infusion, the integrated glycemic response above baseline was higher in the presence of hydrocortisone than during saline infusion (P < 0.05), implying a decrease in net glucose effectiveness (4.42 +/- 0.52 vs. 6.65 +/- 0.83 ml.kg-1.min-1; P < 0.05). To determine whether this defect is attributable to an impaired ability of glucose to suppress glucose production, to stimulate its own uptake, or both, glucose turnover and "hot" (labeled) indexes of glucose effectiveness (GE) were calculated. Hepatic GE was lower during cortisol than during saline infusion (2.39 +/- 0.24 vs. 3.82 +/- 0.51 ml.kg-1.min-1; P < 0.05), indicating a defect in the ability of glucose to restrain its own production. In addition, in the presence of excess cortisol, glucose disappearance was inappropriate for the prevailing glucose concentration, implying a decrease in glucose clearance (P < 0.05). The decrease in glucose clearance was confirmed by the higher increment in [3-3H]glucose during hydrocortisone than during saline infusion (P < 0.05), despite the administration of identical tracer infusion rates. In conclusion, short-term hypercortisolemia in healthy individuals with normal beta-cell function decreases insulin action but does not alter rates of EGR and gluconeogenesis. In addition, cortisol impairs the ability of glucose to suppress its own production, which due to accumulation of glucose in the glucose space results in impaired peripheral glucose clearance. These results suggest that cortisol excess impairs glucose tolerance by decreasing both insulin action and glucose effectiveness.
Development of Flapping-wing Robot with Independently Controllable Wings (2021)

Most flapping-wing robots use a single motor to flap both wings. Independent wing control has the potential to improve maneuverability. However, this approach tends to increase the weight and makes it difficult to take off. We developed a lightweight servo motor and a flapping-wing robot with independently controllable wings. We conducted a vertical takeoff experiment and confirmed that the robot had the capability to take off without the need of a launcher.
Anti-Mycobacterial Screening of British Columbian Medicinal Plants (1997)

One hundred methanol plant extracts were screened for antibiotic activity against Mycobacterium tuberculosis and Mycobacterium avium. Nineteen extracts exhibited some activity against M. tuberculosis and 16 extracts showed some activity against M. avium. Thirteen of these 19 active extracts were traditionally used by First Nations peoples to treat tuberculosis. Extracts made from Heracleum maximum (Umbelliferae) roots, Moneses uniflora (Ericaceae), aerial parts, and Oplopanax horridus (Araliaceae) inner bark completely inhibited the growth of both organisms at a concentration equivalent to 20 mg dried plant material/disc. Extracts of Alnus rubra (Betulaceae) bark and catkins, Empetrum nigrum (Empetraceae) branches, Glehnia littoralis (Umbelliferae) roots, and Lomatium dissectum (Umbelliferae) roots completely inhibited the growth of both M. tuberculosis and M. avium at a concentration equivalent to 100 mg dried plant material/disc.
Thermal Agglomeration of Ultrathin SOI and SSOI Films: A Quantitative Stability Study and Physical Model to Guide Ultrathin SOI Process Design (2006)

We present the results of a controlled experimental study of the thermal agglomeration of (100)-oriented ultra-thin SOI films along with a surface-energy-driven physical model for SOI agglomeration to guide ultra-thin SOI process design. Through a UHV annealing study, the SOI agglomeration edge initiation time and edge propagation velocity were determined as a function of SOI thickness and annealing temperature for bonded and SiMOX SOI films. SiMOX SOI and strained SOI films were studied and shown to have nearly identical agglomeration behavior to bonded SOI films, clearly indicating that SOI agglomeration is not a stress-driven phenomenon. An ultra-thin SOI defect study was also performed in parallel with this agglomeration study to identify the defect responsible for bulk SOI agglomeration initiation. HF defects, dislocations, and stacking faults were ruled out and initial evidence indicates that defects at the top Si/buried SiO2 interface may be responsible.
The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells (2019)

Resistance to 5-Fluorouracil chemotherapy is a major cause of therapeutic failure in colon cancer cure. Development of combined therapies constitutes an effective strategy to inhibit cancer cells and prevent the emergence of drug resistance. For this purpose, we investigated the anti-tumoral effect of thirteen phenolic compounds, from the Tunisian quince Cydonia oblonga Miller, alone or combined to 5-FU, on the human 5-FU-resistant LS174-R colon cancer cells in comparison to parental cells. Our results showed that only Kaempferol was able to chemo-sensitize 5-FU-resistant LS174-R cells. This phenolic compound combined with 5-FU exerted synergistic inhibitory effect on cell viability. This combination enhanced the apoptosis and induced cell cycle arrest of both chemo-resistant and sensitive cells through impacting the expression levels of different cellular effectors. Kaempferol also blocked the production of reactive oxygen species (ROS) and modulated the expression of JAK/STAT3, MAPK, PI3K/AKT and NF-κB. In silico docking analysis suggested that the potent anti-tumoral effect of Kaempferol, compared to its two analogs (Kaempferol 3-O-glucoside and Kampferol 3-O-rutinoside), can be explained by the absence of glucosyl groups. Overall, our data propose Kaempferol as a potential chemotherapeutic agent to be used alone or in combination with 5-FU to overcome colon cancer drug resistance.
TESTING AND EVALUATION OF MOLDED PLASTIC MAILBOXES (2001)

Under this project, researchers investigated the impact performance of molded plastic mailboxes through full-scale crash testing. The Texas Department of Transportation has been receiving an increasing number of requests to use these molded plastic mailboxes in lieu of the Department's standard mailbox support and mailbox connection hardware. These molded plastic mailboxes are available in a variety of styles and colors, which make them an aesthetic alternative to conventional mailbox installations. Crash tests were conducted to evaluate the performance of molded plastic mailboxes on three different types of support posts: 4x4 wood, 2 lb/ft U-channel, and 3-in. diameter schedule 40 pipe. In all three tests, the molded plastic mailbox units satisfied National Cooperative Highway Research Program (NCHRP) Report 350 evaluation criteria. However, some variations in performance associated with the different support posts were observed. From both a functional and impact performance standpoint, the 4x4 timber support post appears to be the best alternative from among the three support posts investigated. It is therefore recommended that these mailboxes be installed on a 4x4 wood support post per manufacturers' recommendations.
Compact Multi-domain Models for Control of Fuel Cell Systems (2005)

Power generation from Fuel Cells (FC) requires the integration of chemical, fluid, mechanical, thermal, electrical, and electronic subsystems. In this presentation we highlight the development of a physics based model that enables the accurate prediction of water generation and flow through the FC membrane. The missing model parameters are identified from measurements of controlled experiments. This model accurately predicts the behavior of the FC and can be used for control design, however, its complexity can be prohibitive. To this end, a review of model reduction procedures and how they can be implemented to this model in order to develop a simpler yet accurate model is included.
Mechanical introscopy-a new modality of medical imaging for detection of breast and prostate cancer (2002)

Summary form only given. Mechanical introscopy is based on the reconstruction of the internal structure of soft body tissues by measuring the surface distribution of stress/strain patterns using a pressure sensor array. This new technology of medical imaging does not use any form of potentially hazardous radiation. It provides information on the internal structure of the organ and enables physicians to obtain values of the elasticity modulus of internal lesions and to characterize their hardness, which is indicative of cancer development. This paper presents the results of mathematical simulation and model experiments on visualizing the structure and evaluating the properties of internal tissues from a pattern of mechanical stresses developed by an array of pressure sensors that is pressed statically or dynamically against investigated tissues or a body part. The resulting pattern of mechanical stress and its changes as a function of applied pressure and time contain comprehensive information on the mechanical properties and geometry of the internal structures which can be calculated from the pattern by solving the inverse problem. Mechanical introscopy meets all the requirements for a mass cancer screening method: it is simple, fast, inexpensive and safe.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Acute Exogenous Lipoid Pneumonitis Following Siphoning of Diesel Fuel: A Case Report (2019)

Acute exogenous lipoid pneumonitis is a kind of chemical pneumonitis following the aspiration of volatile hydrocarbon compounds. The clinical and radiological findings are nonspecific.
PiCL: A Software-Transparent, Persistent Cache Log for Nonvolatile Main Memory (2018)

Software-transparent crash consistency is a promising direction to immediately reap the benefits of nonvolatile main memory (NVMM) without encumbering programmers with error-prone transactional semantics. Unfortunately, proposed hardware write-ahead logging (WAL) schemes have high performance overhead, particularly for multi-core systems with many threads and big on-chip caches and NVMs with low random-access performance. This paper proposes PiCL, a new WAL checkpointing mechanism that provides a low overhead, software-transparent crash consistency solution for NVMM. PiCL introduces multi-undo logging, cache-driven logging, and asynchronous cache-scan to reduce random accesses and enable good row locality at the NVM. The key idea is that: by relaxing the durability timing of checkpoints, crash consistency can be provided with less than 1% performance overhead where 1.5x to 5.0x slowdown was typical with prior work. To demonstrate the feasibility of software-transparent crash consistency, we fully implemented PiCL as an FPGA prototype in Verilog using the OpenPiton framework.
HYDROTHERMAL LIQUEFACTION OF MICROALGAE IN THE PRESENCE OF HOMOGENEOUS AND HETEROGENEOUS CATALYSTS (2015)

The continuous raise in the prices of fossil fuels and the awareness of the society challenges related to their use has recently driven a strong growth of interest on the investigation of different biochemical or thermochemical processes for the production of liquid biofuels .
Ventilation and arousal responses to hypercapnia in normal sleeping humans (1984)

We measured arousal and ventilatory responses to rebreathing from a small bag, initially approximately 7% CO2 in 40% O2, via a nose mask in 13 normal human adults. With deepening non-rapid-eye-movement sleep (NREM), males aroused at increasing alveolar PCO2 (mean +/- SE: stage II 58.6 +/- 1.7, stage III 61.2 +/- 1.0, stage IV 63.8 +/- 0.8 Torr), whereas in rapid-eye-movement sleep (REM), arousal alveolar PCO2 was 57.7 +/- 0.7 Torr, i.e., much lower than in stage III and IV NREM. Females showed no significant change in arousal alveolar PCO2, (II 57.6 +/- 0.9, III 57.3 +/- 1.3, IV 59.4 +/- 0.9, REM 56.3 +/- 1.0 Torr). Male ventilatory response was 2.5 +/- 0.1 (SE) 1 X min-1 X Torr-1 and fell by 49% in NREM (1.29 +/- 0.13) and by 69% in REM (0.78 +/- 0.18). Female response was little affected by state, being similar to male NREM response (wake 1.39 +/- 0.14, NREM 1.40 +/- 0.13, REM 1.11 +/- 0.26 1 X min-1 X Torr-1). In NREM tests, there was no change in sleep state until arousal, whereas in REM, subjects awoke abruptly with the onset of rebreathing (11 cases), showed a transient arousal with onset but continued in REM until final arousal (21 cases), or changed to NREM at onset (2 cases). These arousal results contrast sharply with findings in tracheostomized dogs and in obstructive sleep apnea syndrome, where asphyxic arousal is later in REM than in NREM, suggesting that the events at test onset in REM in the present study may be related to upper airway sensitivity to CO2 specific to REM.
Functionalization of a poly(vinyl alcohol) in the solid state with a swelling agent by methacrylic anhydride (2004)

Abstract Poly(vinyl alcohol‐ co ‐vinyl acetate) was functionalized by methacrylic anhydride to introduce functional groups by a new process that consisted of modifying a polymer directly from a powder form in the solid state. To favor the diffusion of the reagents, a swelling agent composed by a mixture of ethylene carbonate and propylene carbonate was used. N ‐methylimidazole was used as a basic catalyst of the esterification reaction, adjusting the reaction times. This work presents the process and the effects of the formulation on anhydride conversion. The side reactions were also determined; they all involved N ‐methylimidazole. Decarboxylation reactions of the carbonates were characterized, that is, going from ethylene carbonate to ethylene glycol, which is able to react with two anhydride molecules by esterification reactions to, respectively, form 2‐hydroxyethyl 2‐methylpropenoate and ethyl 1,2‐bis(2‐methyl propenoate). The same side reactions are possible with propylene carbonate but are less reactive than the starting ethylene carbonate. Model anhydrides such as hexanoic and heptanoic anhydrides, less reactive than methacrylic anhydride, were used to characterize a new anhydride decarboxylation reaction. The homogeneity of the grafting is also discussed, especially its dependence on the polymer properties, the diffusion modes of the reagents (carbonate mixture and the anhydride), and the competition between the diffusional and chemical kinetics of methacrylic anhydride. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 42: 1618–1629, 2004