gebhart/patrepeval huggingface dataset:
The Selective Oxidation of Cyclohexane via In-situ H2O2 Production Over Supported Pd-based Catalysts (2021)

Abstract The oxidation of cyclohexane via the in-situ production of H 2 O 2 from molecular H 2 and O 2 offers an attractive route to the current industrial means of producing cyclohexanone and cyclohexanol (KA oil), key materials in the production of Nylon. The in-situ route has the potential to overcome the significant economic and environmental concerns associated with the use of commercial H 2 O 2 , while also allowing for the use of far lower reaction temperatures than those typical of the purely aerobic route to KA oil. Herein we demonstrate the efficacy of a series of bi-functional Pd-based catalysts, which offer appreciable concentrations of KA oil, under conditions where limited activity is observed using O 2 alone. In particular the introduction of V into a supported Pd catalyst is seen to improve KA oil concentration by an order of magnitude, compared to the Pd-only analogue. In particular we ascribe this improvement in catalytic performance to the development of Pd domains of mixed oxidation state upon V incorporation as evidenced through X-ray photoelectron spectroscopy. Graphic Abstract
The Temporal Variation of a Saltwater Contaminant Plume as Evidenced through Long‐Term Resistivity Monitoring (1999)

PreviousNext No AccessSymposium on the Application of Geophysics to Engineering and Environmental Problems 1999The Temporal Variation of a Saltwater Contaminant Plume as Evidenced through Long‐Term Resistivity MonitoringAuthors: Gail LipfertStewart SandbergLee SlaterAndrew ReeveMarc LoiselleGail LipfertDepartment of Geological Sciences, University of Maine, Orono, ME 04469., Stewart SandbergDepartment of Geosciences, University of Southern Maine, Gorham, ME 04038., Lee SlaterDepartment of Geosciences, University of Southern Maine, Gorham, ME 04038., Andrew ReeveDepartment of Geological Sciences, University of Maine, Orono, ME 04469., and Marc LoiselleDepartment of Conservation, State House Station 22, Augusta Maine 04333.https://doi.org/10.4133/1.2922644 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Abstract Introductory paragraph for this paper is available only in the PDF and GZipped PS filesPermalink: https://doi.org/10.4133/1.2922644FiguresReferencesRelatedDetailsCited ByGeophysical Monitoring Through a Tidal Cycle at Crescent Beach State Park, MaineStewart K. Sandberg and Lee D. Slater27 April 2012 | Journal of Environmental and Engineering Geophysics, Vol. 6, No. 4 Symposium on the Application of Geophysics to Engineering and Environmental Problems 1999ISSN (online):1554-8015Copyright: 1999 Pages: 997 publication data© 1999 Copyright © 1999 The Environmental and Engineering Geophysical SocietyPublisher:Environmental & Engineering Geophysical Society HistoryPublished: 30 Sep 2008 CITATION INFORMATION Gail Lipfert, Stewart Sandberg, Lee Slater, Andrew Reeve, and Marc Loiselle, (1999), "The Temporal Variation of a Saltwater Contaminant Plume as Evidenced through Long‐Term Resistivity Monitoring," Symposium on the Application of Geophysics to Engineering and Environmental Problems Proceedings : 497-506. https://doi.org/10.4133/1.2922644 Plain-Language Summary PDF DownloadLoading ...
1kW fiber-coupled pump-module at 976nm with 50% efficiency (2017)

We present a fiber-coupled pump-module emitting more than 1kW of mode-stripped power at 976nm from a detachable 225µm, 0.22NA fiber. The electrical-to-optical efficiency at 1kW is ~50%. Six of these pump modules attached to a (6 + 1):1 multimode combiner enable a 5-6kW, single-mode, Yb-doped fiber amplifier.
High sensitive structure and its fabrication process for MEMS fingerprint sensor to various fingers (2004)

This paper describes a novel structure of MEMS (microelectromechanical systems) and its fabrication process on the surface of the MEMS fingerprint sensor that works as an interface between a finger and the sensor. In order to detect fingerprints, whether a finger is soft or hard, novel T-shaped protrusions are proposed. The structure was fabricated by etching a sacrificial layer on the cavity structure that has a pair of electrodes. Structural calculations and experimental measurements showed that the proposed sensor bends the electrode most efficiently. This enables fingerprint detection regardless of finger elasticity, and enhances sensitivity for various finger surface conditions.
Next Generation Wireless LANs: 802.11n and 802.11ac (2013)

If you've been searching for a way to get up to speed on IEEE 802.11n and 802.11ac WLAN standards without having to wade through the entire specification, then look no further. This comprehensive overview describes the underlying principles, implementation details and key enhancing features of 802.11n and 802.11ac. For many of these features the authors outline the motivation and history behind their adoption into the standard. A detailed discussion of key throughput, robustness, and reliability enhancing features (such as MIMO, multi-user MIMO, 40/80/160 MHz channels, transmit beamforming and packet aggregation) is given, plus clear summaries of issues surrounding legacy interoperability and coexistence. Now updated and significantly revised, this 2nd edition contains new material on 802.11ac throughput, including revised chapters on MAC and interoperability, plus new chapters on 802.11ac PHY and multi-user MIMO. An ideal reference for designers of WLAN equipment, network managers, and researchers in the field of wireless communications.
Data from Methylation of <i>TFPI2</i> in Stool DNA: A Potential Novel Biomarker for the Detection of Colorectal Cancer (2023)

&lt;div&gt;Abstract&lt;p&gt;We have used a gene expression array–based strategy to identify the methylation of tissue factor pathway inhibitor 2 (&lt;i&gt;TFPI2&lt;/i&gt;), a potential tumor suppressor gene, as a frequent event in human colorectal cancers (CRC). &lt;i&gt;TFPI2&lt;/i&gt; belongs to the recently described group of embryonic cell Polycomb group (&lt;i&gt;PcG&lt;/i&gt;)–marked genes that may be predisposed to aberrant DNA methylation in early stages of colorectal carcinogenesis. Aberrant methylation of &lt;i&gt;TFPI2&lt;/i&gt; was detected in almost all CRC adenomas (97%, &lt;i&gt;n&lt;/i&gt; = 56) and stages I to IV CRCs (99%, &lt;i&gt;n&lt;/i&gt; = 115). We further explored the potential of &lt;i&gt;TFPI2&lt;/i&gt; as a biomarker for the early detection of CRC using stool DNA–based assays in patients with nonmetastatic CRC and average-risk noncancer controls who were candidates for screening. &lt;i&gt;TFPI2&lt;/i&gt; methylation was detected in stool DNA from stage I to III CRC patients with a sensitivity of 76% to 89% and a specificity of 79% to 93%. Detection of &lt;i&gt;TFPI2&lt;/i&gt; methylation in stool DNA may act as a useful adjunct to the noninvasive strategies for screening of CRCs in the future. [Cancer Res 2009;69(11):4691–9]&lt;/p&gt;&lt;/div&gt;
Synthesis of Enatiopure Fluorine-Containing Taxoids and Their Use as Anticancer Agents as well as Probes for Biomedical Problems (1999)

A series of fluorine-containing analogs of paclitaxel and docetaxel are synthesized through the coupling of (3R,4S)-1-acyl-β-lactams of high enantiomeric purity with various baccatin derivatives as the key step. Some taxoids bearing CF3 or CF2H at the C-3' position are up to three orders of magnitude more porent than paclitaxel or doxorubin against human breast cancer cell lines, including those that are drug resistant. Metaboism studies show that fluorinated taxoid block the action of cytochrome P-450s. A combination of 19F and 1H NMR analyses with molecular modeling has disclosed a previously unrecognized conformer that may be the first structure to be recognized by microtubles and the one tightly bound to the protein.
In Vivo Response of Polylactic Acid–Alginate Scaffolds and Bone Marrow-Derived Cells for Cartilage Tissue Engineering (2005)

Successful application of tissue-engineering techniques to damaged biological structures is determined by functional performance in vivo. This study evaluated the in vivo response of a tissue-engineered construct composed of a polylactic acid–alginate amalgam seeded with bone marrow-derived mesenchymal stem cells and stimulated in vitro with transforming growth factor β for cartilage tissue engineering. Constructs were placed in cylindrical osteochondral defects in the canine femoral condyle and examined 6 weeks postoperatively by gross, histological, immunohistochemical, and biomechanical analyses. In the course of 6 weeks in vivo, the defects filled with a cartilaginous tissue regardless of whether cell-seeded (experimental) or cell-free (control) constructs were implanted; however, the quality of the tissue differed between the experimental and control defects. Cell-seeded experimental defects showed more cartilage-like matrix quality, cell distribution, and proteoglycan staining. Biomechanically, experimental and control specimens exhibited similar behavior; however, both tissues were still immature compared with normal cartilage. The evidence accumulated in this study showed a modest acceleration of the in vivo healing of cellseeded constructs but also demonstrated a reparative response of cell-free constructs. This finding suggests that the constructs prepared from the PLA–alginate amalgam may serve as a means for host cell attachment.
ChemInform Abstract: Synthesis of Bis(trifluoromethylated)Pyrazine‐containing Nitrogen Heterocycles from Hexafluorobiacetyl and ortho‐Diamines. Stabilization of the Covalent Dihydrates of Pteridines and Pyrido[3,4‐b]pyrazines by Trifluoromethyl Groups. (1986)

Abstract Perfluorobutane‐2,3‐dione (I) reacts with the ortho‐diamines (II) to give the quinoxalines (III).
Multimodal segmentation of lifelog data (2007)

A personal lifelog of visual and audio information can be very helpful as a human memory augmentation tool. The SenseCam, a passive wearable camera, used in conjunction with an iRiver MP3 audio recorder, will capture over 20,000 images and 100 hours of audio per week. If used constantly, very soon this would build up to a substantial collection of personal data. To gain real value from this collection it is important to automatically segment the data into meaningful units or activities. This paper investigates the optimal combination of data sources to segment personal data into such activities. 5 data sources were logged and processed to segment a collection of personal data, namely: image processing on captured SenseCam images; audio processing on captured iRiver audio data; and processing of the temperature, white light level, and accelerometer sensors onboard the SenseCam device. The results indicate that a combination of the image, light and accelerometer sensor data segments our collection of personal data better than a combination of all 5 data sources. The accelerometer sensor is good for detecting when the user moves to a new location, while the image and light sensors are good for detecting changes in wearer activity within the same location, as well as detecting when the wearer socially interacts with others.
Exciton-blocking treatments for buffer layers in organic photovoltaics (2023)

Disclosed herein are exciton-blocking treatments for buffer layers used in organic photosensitive optoelectronic devices. More specifically, the organic photosensitive optoelectronic devices described herein include at least one self-assembled monolayer disposed on the surface of an anode buffer layer. Methods of preparing these devices are also disclosed. The present disclosure further relates to methods of forming at least one self-assembled monolayer on a substrate.
Recurrent Myocardial Infarction After Primary Percutaneous Coronary Intervention in Multivessel Coronary Disease Is Primarily Related to Stent Failure (2015)

In this post-hoc analysis of the PASSION trial, recurrent MI in patients with MVD was mainly related to stent failure rather than a new event originating from a significant stenosis in a non-culprit coronary artery.
BIVV001, a new class of factor VIII replacement for hemophilia A that is independent of von Willebrand factor in primates and mice (2020)

Factor VIII (FVIII) replacement products enable comprehensive care in hemophilia A. Treatment goals in severe hemophilia A are expanding beyond low annualized bleed rates to include long-term outcomes associated with high sustained FVIII levels. Endogenous von Willebrand factor (VWF) stabilizes and protects FVIII from degradation and clearance, but it also subjects FVIII to a half-life ceiling of ∼15 to 19 hours. Increasing recombinant FVIII (rFVIII) half-life further is ultimately dependent upon uncoupling rFVIII from endogenous VWF. We have developed a new class of FVIII replacement, rFVIIIFc-VWF-XTEN (BIVV001), that is physically decoupled from endogenous VWF and has enhanced pharmacokinetic properties compared with all previous FVIII products. BIVV001 was bioengineered as a unique fusion protein consisting of a VWF-D'D3 domain fused to rFVIII via immunoglobulin-G1 Fc domains and 2 XTEN polypeptides (Amunix Pharmaceuticals, Inc, Mountain View, CA). Plasma FVIII half-life after BIVV001 administration in mice and monkeys was 25 to 31 hours and 33 to 34 hours, respectively, representing a three- to fourfold increase in FVIII half-life. Our results showed that multifaceted protein engineering, far beyond a few amino acid substitutions, could significantly improve rFVIII pharmacokinetic properties while maintaining hemostatic function. BIVV001 is the first rFVIII with the potential to significantly change the treatment paradigm for severe hemophilia A by providing optimal protection against all bleed types, with less frequent doses. The protein engineering methods described herein can also be applied to other complex proteins.
Photoacoustic Sensor Using Silicon Piezoresistor for Non-Invasive Measurement of Glucose (2023)

This paper introduces a Photoacoustic Spectroscopy (PAS) sensor using a highly sensitive pressure sensor composed of silicon piezoresistive cantilever for continuous non-invasive measurement of blood glucose. By measuring photoacoustic waves generated by far-infrared light with the silicon piezoresistive cantilever, the sensor can measure the photoacoustic waves without resonator. This enables to miniaturize the sensor size. The minimum resolution of the silicon piezoresistive cantilever was about 10 µPa, and we confirmed that the prototype PAS sensor can be used to measure 60 mg/dL density glucose in liquid.
Interaction of various intracellular signaling mechanisms involved in mononuclear phagocyte toxicity toward neuronal cells (2000)

Microglia become activated in a wide range of neurodegenerative disorders, including Alzheimer's disease. Such activation may lead to autodestruction of neurons. It is demonstrated here that activation of both human microglia and monocytic THP-1 cells by a combination of lipopolysaccharide and interferon-gamma results in secretion of neurotoxins that kill human neuronal SH-SY5Y cells. This neurotoxicity can be partially blocked by inhibitors of cytosolic phospholipase A2, cGMP-selective phosphodiesterases, or protein kinase C. When combinations of these inhibitors, or combinations of an inhibitor plus nordihydroguaiaretic acid, or the nonsteroidal anti-inflammatory drug diclofenac were tried, additive reductions in neurotoxicity were observed. It is concluded that the stimulants activated multiple intracellular pathways, and that combination therapies inhibiting these pathways might be beneficial for treating neurodegenerative disorders.
Author Correction: Fast and multiplexed superresolution imaging with DNA-PAINT-ERS (2020)

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Synthesis and Characterization of Chiral Periodic Mesoporous Organosilicas (2007)

Keep this handy! Periodic mesoporous organosilica-based compounds with chiral channels are prepared by using an achiral fluorinated surfactant (FC-4911) and cetyltrimethylammonium bromide as structure-directing agents. Spiral samples synthesized from 1,4-bis(triethoxysilyl)benzene exhibit structural periodicity and a crystal-like mesoporous wall (see TEM image).
Bridging Screen Readers and Voice Assistants for Enhanced Eyes-Free Web Search (2019)

People with visual impairments often rely on screen readers when interacting with computer systems. Increasingly, these individuals also make extensive use of voice-based virtual assistants (VAs). We conducted a survey of 53 people who are legally blind to identify the strengths and weaknesses of both technologies, as well as the unmet opportunities at their intersection. We learned that virtual assistants are convenient and accessible, but lack the ability to deeply engage with content (e.g., read beyond the first few sentences of Wikipedia), and the ability to get a quick overview of the landscape (list alternative search results & suggestions). In contrast, screen readers allow for deep engagement with content (when content is accessible), and provide fine-grained navigation & control, but at the cost of increased complexity, and reduced walk-up-and-use convenience. In this demonstration, we showcase VERSE, a system that combines the positive aspects of VAs and screen readers, and allows other devices (e.g., smart watches) to serve as optional input accelerators. Together, these features allow people with visual impairments to deeply engage with web content through voice interaction.
Alternative Method of Intraocular Foreign-Body Localization (1984)

Anteroposterior (AP) and lateral films are obtained simultaneously, and superimposed on them is the shadow of a pair of cross wires representing the center of the pupil in the AP projection and the front surface of the cornea in the lateral projection. This is achieved by the use of a frame on which are mounted three sighting devices. Each sight is like a simple gunsight with two sets of cross hairs 80 mm apart; one of the cross hairs is radiolucent, and the other is radiopaque so as to be superimposed on the x-ray film. Two of the sights are mounted horizontally and are coaxial. These are the sights used for lateral projections; one is used for right eye localization and the other when left eye localization is required. These sights are positioned by adjusters in vertical and horizontal directions. The third sight is mounted vertically for the AP projection and can be adjusted laterally over a range covering both eyes. The center axis of this sight intersects the center axis of the lateral sights and moves with them if they are adjusted in a horizontal direction (inferior-superior movement with respect to the patient). In use, the patient is supine, the head is positioned on a thin foam pad between the lateral sights, and the neck is extended so that the outer canthus-external auditory canal baseline is 25#{176} to the perpendicular. The head is immobilized by means of a restraining band, and the sights are adjusted over the center of the pupil in the AP projection and to the front surface of the cornea in the lateral. The x-ray tubes are then positioned with the central ray in the axes of the sighting devices. The AP film is placed in a tunnel beneath the patient’s head, and the lateral film positioned next to the head on the contralateral side from the eye being examined (fig. 1). Simultaneous biplane exposures are taken, if possible with the patient’s eyes open and looking at the light beam collimator of the overhead tube. A focus-film distance of 1 200 mm is used for both projections to provide a standard magnification factor of 1 .2:1 (fig. 2). When necessary, plotting of the foreign body on an eye localization chart is achieved by taking direct measurements of the foreign body from the reference point (the pupil and front surface of the cornea) and transposing these measurements onto the chart after making appropriate allowance for magnification.
The unexpected discovery of the Mg(HMDS)2/MgCl2 complex as a magnesium electrolyte for rechargeable magnesium batteries (2015)

We developed a unique class of non-Grignard, aluminum-free magnesium electrolytes based on a simple mixture of magnesium compounds: magnesium hexamethyldisilazide (Mg(HMDS)<sub>2</sub>) and magnesium chloride (MgCl<sub>2</sub>).
Chromatin Structure in Living Cells (1978)

Psoralen and its derivatives intercalate in the DNA helix. In the presence of 360-nm light, psoralen undergoes photochemical reactions with pyrimidine bases. When one psoralen molecule reacts with two pyrimidines on opposite strands of the double helix, a stable cross-link is formed between the two polynucleotide strands (Cole 1970, 1971; Dall'Acqua et al. 1970). The cross-linking reaction can be performed easily in living cells, with no detectable reaction with proteins (Pathak and Kramer 1969; Cole 1970; Musajo and Rodighiero 1970; Cech and Pardue 1976).
MITes: Wireless Portable Sensors for Studying Behavior (2004)

We present MITes (MIT Environmental Sensors): a portable kit of ubiquitous wireless sensing devices for realtime data collection of human activities in natural settings. The sensors designed to be used in two ways: (1) determining people’s interaction with objects in the environment, and (2) measuring acceleration on different parts of the body. The sensors have been designed to permit low-cost research studies where data is acquired simultaneously from hundreds of objects in an environment and multiple parts of the body.
Reduced poly-Si TFT threshold voltage instability by high-temperature hydrogenation of a-Si-like spin centers (1995)

New findings of this work are as follows: a-Si-like spin centers (.Si/spl equiv/Si/sub 3/) are found to exist in CVD-SiO/sub 2/ gate dielectric films as well as poly-Si substrate films. High-temperature hydrogenation (HTH) at 850/spl deg/C is effective in terminating these spin centers and in reducing the poly-Si PMOS TFT threshold voltage instability.
All-optical interconnects for massively parallel processing (2002)

We describe a flexible all-optical interconnect scheme for massively parallel processing, capable of providing 250 channels and an information capacity of 250 Gb/s. Using available and/or demonstrated technologies, we can build fully tunable transmitter arrays and receivers. These essentially act to create a randomly, accessible 250/spl times/250 crossbar switch, connecting up to 500 processors in a single-level system. The multiplexing and de-multiplexing can be done with sufficient speed to satisfy requirements for massive parallel processing. The crossbar switch can provide 250000 1-Mb packet connections per second. A multi-level system can provide thousands to millions of simultaneous connections, at the cost of greater control complexity. A reservation scheme for the control of the one- and two-level switch is illustrated and computer simulation of the scheme demonstrated. We also propose a "pilot" token scheme for the multi-channel Express Bus (E-bus) on which packet switching can be performed. We believe that recent advancements have made the system technically feasible, and (with OEIC integration) practical and cost effective. Other related interconnect/network issues are discussed.
Novel rapid‐cure adhesives for low temperature using thiirane compound (2001)

Abstract We investigated improvement of workability (viscosity), storage stability, and curing ability of thiirane resin for adhesive applications. The viscosity of bisphenol‐F thiirane resin was lower than that of bisphenol‐A thiirane resin, especially at low temperatures, thus improving ease of handling. Addition of diphenyl decyl phosphite improved its storage stability to a level similar to that of bisphenol‐A epoxy resin. The curing of bisphenol‐F thiirane resin increased three times faster by adding 2,4,6‐tris(dimethylaminomethyl)phenol (DMP‐30) as a tertiary amine. In applications of this new thiirane resin as civil and architectural adhesives, a superior curing ability at low temperature was attained. © 2001 John Wiley &amp; Sons, Inc. J Appl Polym Sci 82: 2953–2957, 2001