gebhart/patrepeval huggingface dataset:
Weissella kimchii sp. nov., a novel lactic acid bacterium from kimchi. (2002)

A gram-positive, catalase-negative, non-sporulating, facultatively anaerobic, short rod-shaped bacterium, with cells measuring 0.3-0.5 x 1-2 microm and designated strain CHJ3T, was isolated from partially fermented kimchi, a traditional Korean fermented vegetable food. The strain produced CO2 gas, D-lactate from glucose and dextran from sucrose and hydrolysed aesculin and arginine. It also fermented N-acetylglucosamine, amygdalin, arbutin, cellobiose, D-fructose, galactose, beta-gentiobiose, gluconate, D-glucose, maltose, D-mannose, salicin, sucrose and D-xylose. The G+C content of the DNA was 48.2 mol%. Phylogenetic analysis of 16S rRNA showed that strain CHJ3T is a member of the genus Weissella. The nearest phylogenetic relative of strain CHJ3T was Weissella confusa, with 16S rRNA similarity of 98.3%. However, strain CHJ3T could be differentiated from W. confusa on the basis of some phenotypic characteristics, analysis of whole-cell protein patterns and DNA-DNA hybridization data. These data suggest that strain CHJ3T be classified in the genus Weissella as a novel species, Weissella kimchii sp. nov. The type strain is CHJ3T (= KCCM 41287T = DSM 14295T = KCTC 3746T).
Pure angular momentum generator using a ring resonator (2010)

This paper reports a pure angular momentum generator using a ring resonator surrounded by a group of nano-rods. The evanescent waves of the circulating light in the ring are scattered by the nano-rods and generate a rotating electromagnetic field, which has only angular momentum but no linear momentum along the axis of rotation. The angular order is determined by the difference between the order of Whispering Gallery mode and the number of the rods, the rotating frequency is equal to the light frequency divided by the angular order. The maximum amplitude of the rotating electromagnetic fields can be 10 times higher than the amplitude of the input field when there are 36 rods (R(rod) = 120 nm, nr = 1.6). The pure angular momentum generator provides a new platform for trapping and rotation of small particles.
Expression of Brucella Antigens in Vaccinia Virus to Prevent Brucellosis in Humans: Protection Studies in Mice (2000)

Abstract : The current work has the overall objectives of genetically engineering mono and poly-valent, IL-12 producing vaccinia/Brucella recombinant vaccines using synthetic E/L promoters and to test such vaccinia recombinants for their ability to induce a protective immune response against challenge with virulent Brucella in a mouse model. For an effective and strongly protective immune response it may he necessary to combine vaccination with vaccinia/Brucella recombinants with the inoculation of DNA vaccines. At this stage the following has been achieved: 1. Demonstrated Brucella Cu/Zn SOD to he a protective antigen. 2. Produced first WRvaccinia/Brucella antigen recombinants simultaneously producing IL-12. 3. Produced first WRvaccinia/Brucella recombinants producing a fusion protein of two protective Brucella antigens (SOD and L7/L12). 4. Initiated protection studies with WRvaccinia/Brucella antigen recombinants producing IL-12. i Detected additional protective Brucella antigens (BMCP24, BaBSC31 and BaPAL16.5) ready for cloning into vaccinia. 6. Produced several Brucella DNA vaccines to he used in combination with WRvaccinia/Brucella antigen recombinants and 7. Initiated production of MVA vaccinia/Brucella antigen recombinants. Based on the identification of protective antigens and the role of IL- 12, we are confident that the use of vaccinia/Brucella recombinants producing IL-12 will induce protective immunity. We are now able to produce such recombinants.
GMPLS Signaling Extension for Optical Transport Networks with Beyond 100G in G.709 Edition 5 (2017)

The International Telecommunication Union Telecommunication
Standardization Sector (ITU-T) has extended its Recommendations G.709
to edition 5 to support beyond 100G (B100G) features. Corresponding
signaling extensions have been described in this document.
Reactions of Coördinated Ligands.1 Acylation of the Coördinated Oxime Group (1961)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of Coördinated Ligands.1 Acylation of the Coördinated Oxime GroupRonald A. Krause, Donald C. Jicha, and Daryle H. BuschCite this: J. Am. Chem. Soc. 1961, 83, 3, 528–531Publication Date (Print):February 1, 1961Publication History Published online1 May 2002Published inissue 1 February 1961https://pubs.acs.org/doi/10.1021/ja01464a005https://doi.org/10.1021/ja01464a005research-articleACS PublicationsRequest reuse permissionsArticle Views160Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Multi-spectral SWIR lidar for imaging and spectral discrimination through partial obscurations (2022)

We have developed a multi-spectral SWIR lidar system capable of measuring simultaneous spatial-spectral information for imaging and spectral discrimination through partial obscurations. We employ objects in the presence and absence of a series of obscurants to evaluate the capability of the system in classifying the objects of interest based on spectral and range information. We employ a principal component analysis-based algorithm in classifying the objects and quantifying the accuracy of detection under various obscured scenarios. The merits of multi-spectral lidar over hyperspectral imaging are highlighted for target identification in the presence of obscurants.
The self-traffic-engineering network (1993)

Characterizes several techniques for the distributed, dynamic management of telecommunications network transmission facilities. Several methods are presented for changing trunk-group sizes in order to respond to extraordinary network loads. These methods are given the generic title of self-traffic-engineering (STE), because the network effectively reengineers itself to adapt to unforeseen circumstances. Self-traffic-engineering is a new network management application for telecommunication facilities networks. One of these methods is based on a new interpretation of network reliability, which is embodied in a metric called connectability. The paper reports the results of a simulation study in which self-traffic-engineering is used to enable the Telecom Canada network to adapt to a focused overload.
An advanced gas/vapor permeation system for barrier materials: Design and applications to poly(ethylene terephthalate) (2012)

Abstract A new gas/vapor mixture permeation system is described to investigate the effect of organic molecules on oxygen (O 2 ) and carbon dioxide (CO 2 ) transport in barrier materials. Methanol vapor was considered as a flavor simulant mainly because of its conveniently high diffusion coefficient, which makes the experimental time accessible. A highly accurate syringe pump was used to introduce a desired activity level of vapor into gas feed stream. Adsorption of methanol on high energy surfaces is carefully characterized to prevent underestimation of methanol permeability. A special permeation cell was also developed to study the effect of interacting vapors on O 2 and CO 2 transport in barrier materials. Systematic permeation measurements were conducted for binary and ternary gas/vapor permeation measurements (e.g., MeOH/O 2 and O 2 /CO 2 /MeOH) to verify the feasibility of our new vapor/gas permeation system. © 2012 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys, 2012
A Pilot Trial of Peripheral Nerve Decompression for Painful Diabetic Neuropathy (P01.125) (2013)

OBJECTIVE: To study clinical and electrophysiologic outcomes of patients undergoing peripheral nerve decompression for painful diabetic neuropathies.
ChemBioOffice Ultra 2010 Suite (2010)

ADVERTISEMENT RETURN TO ISSUEPREVComputer Software Re...Computer Software ReviewNEXTChemBioOffice Ultra 2010 SuiteSean M. KerwinView Author Information University of Texas at AustinCite this: J. Am. Chem. Soc. 2010, 132, 7, 2466–2467Publication Date (Web):February 1, 2010Publication History Published online1 February 2010Published inissue 24 February 2010https://pubs.acs.org/doi/10.1021/ja1005306https://doi.org/10.1021/ja1005306product-reviewACS PublicationsCopyright © 2010 American Chemical SocietyRequest reuse permissionsArticle Views2063Altmetric-Citations89LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Chemical structure,Genetics,Molecular mechanics,Molecular structure,Software Get e-Alerts
Array-Based High-Throughput Analysis of Silk-Elastinlike Protein Polymer Degradation and C-Peptide Release by Proteases (2016)

The objective of this study was to utilize an on-chip degradation assay to evaluate polymer depots and the predicted drug release from the depots. We conjugated four silk-elastinlike protein (SELP) polymers including SELP-815K, SELP-815K-RS1, SELP-815K-RS2, and SELP-815K-RS5 with a Cy5-NHS ester and fabricated SELP arrays by immobilizing the conjugated polymers onto well-type amine arrays. SELP polymer degradation rates were investigated by calculating the half-maximal effective concentration (EC50). Eight cleavage enzymes were applied, all of which exhibited distinctive EC50 values for SELP-815K and its three analogues. We successfully utilized this assay to study the in vitro release of the Cy5-conjugated C-peptide from SELP-815K hydrogel arrays. Additionally, cumulative C-peptide release from the SELP-815K depots was also demonstrated using repetitive elastase treatments. Therefore, this array-based on-chip degradation assay could potentially be used for evaluating depot degradation and controlled drug release from polymer depots at the molecular level.
Prions are a common mechanism for phenotypic inheritance in wild yeasts (2012)

Abstract The self-templating conformations of yeast prion proteins act as epigenetic elements of inheritance. Yeast prions might provide a mechanism for generating heritable phenotypic diversity that promotes survival in fluctuating environments and the evolution of new traits. However, this hypothesis is highly controversial. Prions that create new traits have not been found in wild strains, leading to the perception that they are rare ‘diseases’ of laboratory cultivation. Here we biochemically test approximately 700 wild strains of Saccharomyces for [PSI+] or [MOT3+], and find these prions in many. They conferred diverse phenotypes that were frequently beneficial under selective conditions. Simple meiotic re-assortment of the variation harboured within a strain readily fixed one such trait, making it robust and prion-independent. Finally, we genetically screened for unknown prion elements. Fully one-third of wild strains harboured them. These, too, created diverse, often beneficial phenotypes. Thus, prions broadly govern heritable traits in nature, in a manner that could profoundly expand adaptive opportunities.
IFN-beta2/IL-6 augments the activity of human natural killer cells. (1989)

MHC nonrestricted cytotoxic cells play an important role in the killing of tumor cells in vitro and potentially in vivo. The activity of these cells is regulated by several cytokines such as IL-2 and IFN. In the present study we provide first evidence that IL-6 significantly augments the cytotoxic activity of human NK cells. IL-6 is produced by many different cells and is also known as IFN-beta 2, B cell stimulatory factor 2, hybridoma growth factor, hepatocyte-stimulating factor, and 26 kDa protein. IL-6 stimulates the activity of human CD3- NK cells but not that of CD3+ non-MHC-restricted cytotoxic T lymphocytes. As is the case with IL-2, the IL-6-mediated augmented cytotoxicity was a result of a more efficient lysis, but was not caused by an increased effector to target cell binding. Moreover, the effect of IL-6 on NK cell activity was blocked by a mAb directed against IL-2, and IL-6 itself was found to be a potent inducer of IL-2 production in cultured human PBMC. Thus it may be concluded that IL-6 enhances the cytotoxic activity of NK cells via IL-2. This newly recognized property of IL-6, which is produced by almost any cell, may be of importance in host defense against microbes and malignancies and therefore could contribute to improve the adoptive immunotherapy by using lymphokine-activated killer cells.
Theoretical thermochemistry. 2. Ionization energies and proton affinities of AHn species (A = C to F and Si to Cl); heats of formation of their cations (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTheoretical thermochemistry. 2. Ionization energies and proton affinities of AHn species (A = C to F and Si to Cl); heats of formation of their cationsJohn A. Pople and Larry A. CurtissCite this: J. Phys. Chem. 1987, 91, 1, 155–162Publication Date (Print):January 1, 1987Publication History Published online1 May 2002Published inissue 1 January 1987https://pubs.acs.org/doi/10.1021/j100285a035https://doi.org/10.1021/j100285a035research-articleACS PublicationsRequest reuse permissionsArticle Views184Altmetric-Citations114LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Image harmonization: A review of statistical and deep learning methods for removing batch effects and evaluation metrics for effective harmonization (2023)

Magnetic resonance imaging and computed tomography from multiple batches (e.g. sites, scanners, datasets, etc.) are increasingly used alongside complex downstream analyses to obtain new insights into the human brain. However, significant confounding due to batch-related technical variation, called batch effects, is present in this data; direct application of downstream analyses to the data may lead to biased results. Image harmonization methods seek to remove these batch effects and enable increased generalizability and reproducibility of downstream results. In this review, we describe and categorize current approaches in statistical and deep learning harmonization methods. We also describe current evaluation metrics used to assess harmonization methods and provide a standardized framework to evaluate newly-proposed methods for effective harmonization and preservation of biological information. Finally, we provide recommendations to end-users to advocate for more effective use of current methods and to methodologists to direct future efforts and accelerate development of the field.
Seismic anisotropy estimation in TTI media using walkaway VSP data (2004)

Traveltime modeling and tomographic inversion are popular approaches for estimating overburden anisotropic parameters from walkaway VSP data. When the overburden formations have significant dip, tilted transverse isotropy (TTI) needs to be considered for anisotropic parameter estimation and depth imaging. We have developed a new approach for estimating overburden anisotropic parameters in TTI media. This approach incorporates a fast finite‐difference algorithm for traveltime modeling using 2‐D TTI models. The new method simultaneously estimates Thomsen parameters and updates velocity in the symmetry direction to minimize errors in estimated anisotropic parameters. Our results from a simulation study indicate that the anisotropic parameters are well recovered for test models using this inversion method. A case study also shows improvement in estimated Thomsen parameters.
Increased Expression with Interferon-'y (1984)

The expression ofHLA-DR (a class II histocompatibility antigen) on monocytes isolated from the peripheral blood of normal individuals and patients with acquired immune deficiency syndrome
Demonstration of 1200V Scaled IGBTs Driven by 5V Gate Voltage with Superiorly Low Switching Loss (2019)

Functional trench-gated 1200V-10A class Si-IGBTs, designed based on a three dimensional (3D) scaling concept, were fabricated, and 5V gate voltage switching operation has been demonstrated for the first time. 33% reduction of turn-off loss and 100mV improvement of on-state voltage were achieved, while keeping 1.2kV forward blocking voltage.
Length distributed measurement of temperature effects in Yb-doped fibers during pumping (2014)

We demonstrate a distributed measurement technique to observe temperature changes along pumped Yb-doped fibers. This technique is based on an array of fiber Bragg gratings acting as a temperature sensor line. The Bragg gratings are inscribed directly into the Yb-doped fiber core using high-intensity ultrashort laser pulses and an interferometric setup. We studied the temperature evolution in differently co-doped Yb fibers during optical pumping and identified different effects contributing to the observed temperature increase. We found that preloading of fibers with hydrogen supports the formation of Yb2+ during UV irradiation and has a large impact on fiber temperature during pumping. The proposed technique can be applied to investigate the homogeneity of pump absorption in active fibers and to support spatially resolved photodarkening measurements.
Algorithm and validation of a computer method for quantifying attachment locus of glenohumeral ligamentin vivo (2011)

The aim of this work is to validate an algorithm that quantifies the locus of glenohumeral ligament (GHL) attachments on glenohumeral joint (GHJ) bones. A computed tomography scan of a GHJ was segmented to reconstruct the humerus, scapula, anatomical neck (AN) and glenoid rim (GR) into 3D meshes of interconnecting nodal vectors. These were applied to construct a 'clock face' coordinate system in which 3 o'clock points anteriorly. Based on the assigned clock face coordinate frame and the fitted plane, the error between the fitted plane and the actual bony node was quantified through manual data extraction. This was tested on 50 specimens. Mean algorithm quantification errors for GHL attachments were 4.8 (SD 2.2 mm) and 4.5 mm (1.7 mm) for the humerus and glenoid, respectively. Further studies would apply this to investigate GHL length changes during function and may suggest how these structures should be handled during surgical repairs.
Brain–computer interface devices for patients with paralysis and amputation: a meeting report (2016)

CDRH plans to use this information to develop regulatory considerations that will promote innovation while maintaining appropriate patient protections. FDA plans to build on advances in regulatory science and input provided in this workshop to develop guidance that provides recommendations for premarket submissions for BCI devices. These proceedings will be a resource for the BCI community during the development of medical devices for consumers.
Local field potentials primarily reflect inhibitory neuron activity in human and monkey cortex (2016)

ABSTRACT The local field potential (LFP) is generated by large populations of neurons, but unitary contribution of spiking neurons to LFP is not well characterised. We investigated this contribution in multi-electrode array recordings from human and monkey neocortex by examining the spike-triggered LFP average (st-LFP). The resulting st-LFPs were dominated by broad spatio-temporal components due to ongoing activity, synaptic inputs and recurrent connectivity. To reduce the spatial reach of the st-LFP and observe the local field related to a single spike we applied a spatial filter, whose weights were adapted to the covariance of ongoing LFP. The filtered st-LFPs were limited to the perimeter of 800 μ m around the neuron, and propagated at axonal speed, which is consistent with their unitary nature. In addition, we discriminated between putative inhibitory and excitatory neurons and found that the inhibitory st-LFP peaked at shorter latencies, consistently with previous findings in hippocampal slices. Thus, in human and monkey neocortex, the LFP reflects primarily inhibitory neuron activity.
Reppe‐Carbonylation of Alkenes with Carboxylic Acids: A Catalytic and Mechanistic Study (2022)

Abstract In this work, a green‐catalytic procedure is used to demonstrate the synthesis of long‐chain anhydrides. This is accomplished by the carbonylation of alkenes with carboxylic acids. Anhydrides are important intermediates, finding specific applications as acetylation agents. The process is catalyzed by a Pd phosphine catalyst system in the presence of an acid promotor. Through optimization experiments, the importance of the phosphine ligand and acid promotor is demonstrated, without which the catalyst shows no activity. Although the yield was limited because of catalyst deactivation (42 %), to the best of our knowledge, the synthesis of long‐chain anhydrides through this route have not been reported previously. It therefore represents a significant result. Isolation of the anhydrides were also successfully demonstrated, however, as a result of the sensitivity of the anhydrides to water, the isolated yields were much lower than the HPLC yield. Furthermore, a mechanistic study by means of HP‐NMR (High Pressure Nuclear Magnetic Resonance) spectroscopy provided significant insights into the mechanism of the reaction.
ChemInform Abstract: Tether‐Enforced Reversal of Regioselectivity: Head‐to‐Head (4 + 4) Photocycloaddition of 2‐Pyridones. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.