gebhart/patrepeval huggingface dataset:
N2 Capture Performances of the Hybrid Porous MIL-101(Cr): From Prediction toward Experimental Testing (2017)

The purification of nitrogen-containing gas mixtures, natural/shale gas, and dry air calls for economically viable adsorptive separation processes involving an adsorbent with a higher affinity for N2 over hydrocarbons and oxygen. This led to the discovery of a new class of unprecedented N2-selective metal–organic frameworks (MOFs) with coordinatively unsaturated chromium(III) sites, e.g., MIL-100(Cr) (MIL: Materials of Institut Lavoisier). Following this preliminary study, here grand canonical Monte Carlo simulations identified MIL-101(Cr), an analogue of MIL-100(Cr), as another N2-selective adsorbent from mixtures of both CH4–N2 (natural gas purification) and O2–N2 (air purification). This prediction was further compared to single gas adsorption and breakthrough separation experiments. It was evidenced that only the more energetic coordinatively unsaturated chromium sites released using an activation temperature of 523 K are responsible for the N2-selective behavior of MIL-101(Cr). The separation mechanisms were then elucidated at the molecular-level, and this emphasized the central role played by the concentration of coordinatively unsaturated chromium(III) sites in MIL-101(Cr) that can be controlled by the activation temperature of the sample.
Assignment of Human Myocyte-Specific Enhancer Binding Factor 2C (hMEF2C) to Human Chromosome 5q14 and Evidence That MEF2C Is Evolutionarily Conserved (1995)

Human myocyte-specific enhancer binding factor 2C (hMEF2C) belongs to the MEF2 subfamily of the MADS (MCM1, AGAMOUS, DEF A, serum response factor) family of transcription factors. Members of the MADS family share a conserved domain - the MADS domain - that is necessary for DNA binding. Highly conserved versions of the MADS domain and of an adjacent domain that is known as the MEF2 domain are found in members of the MEF2 subfamily. Both of these domains are necessary for binding to the MEF2 regulatory element. This regulatory element is known to be functionally important in a variety of muscle-specific genes and possibly in the brain creatine kinase gene. The MEF2C gene product activates transcription by binding to the MEF2 element. hMEF2C is expressed at high levels in postmitotic neurons in the brain, where it is most abundant in the cerebral cortex, and is also expressed in differentiated myotubes. Several lines of evidence suggest the existence of a rat homologue of MEF2C, and a mouse homologue has been cloned. The mouse gene was mapped to mouse chromosome 13 in a region that is syntenic to human 5q13-q15. 12 refs., 1 fig.
Amplitude analysis ofB0→D¯0K+π−decays (2015)

The Dalitz plot distribution of ${B}^{0}\ensuremath{\rightarrow}{\overline{D}}^{0}{K}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ decays is studied using a data sample corresponding to $3.0\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ of $pp$ collision data recorded by the LHCb experiment during 2011 and 2012. The data are described by an amplitude model that contains contributions from intermediate ${K}^{*}(892{)}^{0}$, ${K}^{*}(1410{)}^{0}$, ${K}_{2}^{*}(1430{)}^{0}$ and ${D}_{2}^{*}(2460{)}^{\ensuremath{-}}$ resonances. The model also contains components to describe broad structures, including the ${K}_{0}^{*}(1430{)}^{0}$ and ${D}_{0}^{*}(2400{)}^{\ensuremath{-}}$ resonances, in the $K\ensuremath{\pi}$ S-wave and the $D\ensuremath{\pi}$ S- and P-waves. The masses and widths of the ${D}_{0}^{*}(2400{)}^{\ensuremath{-}}$ and ${D}_{2}^{*}(2460{)}^{\ensuremath{-}}$ resonances are measured, as are the complex amplitudes and fit fractions for all components included in the amplitude model. The model obtained will be an integral part of a future determination of the angle $\ensuremath{\gamma}$ of the Cabibbo-Kobayashi-Maskawa quark mixing matrix using ${B}^{0}\ensuremath{\rightarrow}D{K}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ decays.
Effects of Electrical Stimulation in the Inferior Colliculus on Frequency Discrimination by Rhesus Monkeys and Implications for the Auditory Midbrain Implant (2016)

Patients with hearing loss stemming from causes that interrupt the auditory pathway after the cochlea need a brain prosthetic to restore hearing. Recently, prosthetic stimulation in the human inferior colliculus (IC) was evaluated in a clinical trial. Thus far, speech understanding was limited for the subjects and this limitation is thought to be partly due to challenges in harnessing the sound frequency representation in the IC. Here, we tested the effects of IC stimulation in monkeys trained to report the sound frequencies they heard. Our results indicate that the IC can be used to introduce a range of frequency percepts and suggest that placement of a greater number of electrode contacts may improve the effectiveness of such implants.
Massive MIMO With Cauchy Noise: Channel Estimation, Achievable Rate and Data Decoding (2023)

We consider massive multiple-input multiple-output (MIMO) systems in the presence of Cauchy noise. First, we focus on the channel estimation problem. In the standard massive MIMO setup, the users transmit orthonormal pilots during the training phase and the received signal at the base station is projected onto each pilot. This processing is optimum when the noise is Gaussian. We show that this processing is not optimal when the noise is Cauchy and as a remedy propose a channel estimation technique that operates on the raw received signal. Second, we derive uplink-downlink achievable rates in the presence of Cauchy noise for perfect and imperfect channel state information. Finally, we derive log-likelihood ratio expressions for soft bit detection for both uplink and downlink, and simulate coded bit-error-rate curves. In addition to this, we derive and compare the symbol detectors in the presence of both Gaussian and Cauchy noises. An important observation is that the detector constructed for Cauchy noise performs well with both Gaussian and Cauchy noises; on the other hand, the detector for Gaussian noise works poorly in the presence of Cauchy noise. In other words, the Cauchy detector is robust against heavy-tailed noise, whereas the Gaussian detector is not.
Optics in Breast Cancer (2004)

The <i>Journal of Biomedical Optics</i> (JBO) is a Gold Open Access journal that publishes peer-reviewed papers on the use of novel optical systems and techniques for improved health care and biomedical research.
SemanticPaint (2015)

We present a new interactive and online approach to 3D scene understanding. Our system, SemanticPaint , allows users to simultaneously scan their environment whilst interactively segmenting the scene simply by reaching out and touching any desired object or surface. Our system continuously learns from these segmentations, and labels new unseen parts of the environment. Unlike offline systems where capture, labeling, and batch learning often take hours or even days to perform, our approach is fully online. This provides users with continuous live feedback of the recognition during capture, allowing to immediately correct errors in the segmentation and/or learning—a feature that has so far been unavailable to batch and offline methods. This leads to models that are tailored or personalized specifically to the user's environments and object classes of interest, opening up the potential for new applications in augmented reality, interior design, and human/robot navigation. It also provides the ability to capture substantial labeled 3D datasets for training large-scale visual recognition systems.
13‐3: Distinguished Paper: Highly Efficient Deep‐Blue Fluorescent Dopant for Achieving Low‐Power OLED Display Satisfying BT.2020 Chromaticity (2018)

We have succeeded in developing a stable deep‐blue fluorescent dopant which has a shorter emission wavelength and higher emission efficiency than conventional pyrene‐based dopants. It was revealed that the power consumption of a panel using this novel dopant was estimated to be lower than that of a conventional one.
Pretargeted α Emitting Radioimmunotherapy Using 213Bi 1,4,7,10-Tetraazacyclododecane-N,N′,N″,N‴-Tetraacetic Acid-Biotin (2004)

(213)Bi-DOTA-biotin, directed by the Pretarget method to tumor-targeted B3-SA, showed a therapeutic effect, although the therapeutic index was low. The source of the toxicity was most likely related to the renal toxicity.
Relation between cortical dopamine D2 receptor occupancy and suppression of conditioned avoidance response in non‐human primate (2004)

Suppression of the conditioned avoidance response (CAR), a useful test for screening for antipsychotic effects, has been discussed in relation to the blockade of dopaminergic transmission. The purpose of the present paper was to investigate the relationship between cortical dopamine D(2) receptor occupancy and the suppression of CAR by haloperidol in non-human primate. The avoidance rate was measured for four different doses of haloperidol treatment in a rhesus monkey, and the cortical D(2) receptor occupancy was measured in a parallel session using positron emission tomography with [(11)C]FLB 457. The successful avoidance response rate was decreased for doses of 10 and 30 microg/kg of haloperidol, and this decrement was associated with 65-77% of D(2) receptor occupancy. It is suggested that the threshold level of cortical dopamine D(2) receptor occupancy for the suppression of CAR is demonstrated in the present study.
On-Chip Liquid Phase Plasmonic Waveguide with Gold Colloidal Solution (2008)

A plasmonic liquid-liquid (PLL) waveguide using Au nano-particles (NPs) colloidal solution is configured on a micro-optical-fluidic system (Mmicro-optical-fluidic system (MOFSOFS) chip for interest extensions of surface plasmon resonance (SPR) assisted measurements. For characterizing the PLL waveguide, the propagating modes are studied with the scattering images and the measurement of transmission spectrum. Controllability on modes of SPR propagation in PLL waveguide is demonstrated.
Long-term outcome of liver transplants for chronic hepatitis C: a 10-year follow-up (2004)

The analysis of causes leading to graft failure in patients with HCV showed that HCV recurrence is responsible for one of three deaths in HCV-positive patients. Rejection treatment contributed significantly to an enhanced risk for HCV-related graft loss. New antiviral treatments, as well as adapted immunosuppressive protocols, will be necessary to further improve the outcome of HCV-positive patients after liver transplantation.
Constellation Challenges and Contributions of Taiwan Weather Monitoring Satellites (2008)

National Space Organization (NSPO) of Taiwan in the past ten years has successfully launched three different types of satellites. The latest one is FORMOSAT- 3/COSMIC, a joint Taiwan-US project, which was successfully launched on April 15, 2006. The FORMOSAT-3 is a constellation of 6 satellites and each satellite is equipped with GPS Occultation Receiver (GOX), Tri-Band Beacon (TBB), and Tiny Ionospheric Photometer (TIP). The constellation is on the way to its final orbit configuration. All satellites remain healthy except spacecraft flight model no. 2 (FM2) with a problem of power shortage and FM3 currently staying at an orbit of 711 km due to a mechanism issue to be solved. The current sounding profiles retrieved from the GPS occultation measurements are over an average of 1800 daily. The sounding profiles have been used to study atmospheric and ionospheric structures and total electron content, and assimilated into numerical atmospheric and space weather predictions models to improve the accuracy of prediction. Taiwan has taken an active role and grown remarkably well in remote sensing researches during the last decade. Taiwan will continue to share her resources with the international community for scientific research and applications. In this paper, we will present an overview of significant contributions of the FORMOSAT-3/COSMIC satellite mission to the global community. We will also describe the constellation challenges and novel operations solutions and the future follow-on mission planning.
Advanced form of -factor method in analytical electron microscopy (1999)

Journal Article Advanced form of ξ-factor method in analytical electron microscopy Get access Takeshi Fujita, Takeshi Fujita 1Department of Materials Science and Engineering, Faculty of Engineering 36, Kyushu UniversityFukuoka 812-8581, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Masashi Watanabe, Masashi Watanabe 2High Voltage Electron Microscopy Laboratory, Kyushu UniversityFukuoka 812-8581, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Zenji Horita, Zenji Horita 1Department of Materials Science and Engineering, Faculty of Engineering 36, Kyushu UniversityFukuoka 812-8581, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Minoru Nemoto Minoru Nemoto 1Department of Materials Science and Engineering, Faculty of Engineering 36, Kyushu UniversityFukuoka 812-8581, Japan Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Electron Microscopy, Volume 48, Issue 5, 1999, Pages 561–568, https://doi.org/10.1093/oxfordjournals.jmicro.a023716 Published: 01 January 1999 Article history Published: 01 January 1999 Received: 19 January 1999 Accepted: 21 June 1999
Single 808 nm Laser Treatment Comprising Photothermal and Photodynamic Therapies by Using Gold Nanorods Hybrid Upconversion Particles (2018)

Light therapy has become the subject of research on cancer treatment because of its selectivity, low invasive damage, and side effects. Photothermal therapy (PTT) and photodynamic therapy (PDT) are prevalent treatments used to induce cancer cell apoptosis by generating heat and reactive oxygen species (ROS). In this study, mesoporous silica shell-coated gold nanorods (AuNR@mS) are synthesized by seed crystal growth method. AuNR@mS are assembled into nanocomposites through electrostatic adsorption with lanthanide-doped upconversion nanoparticles (UCNP). When controlling the aspect ratio of gold nanorods (AuNRs), the surface plasmon resonance peaks of the short-axis and the long-axis match the maximum absorption cross section at 520 and 660 nm of the fluorescence light released by the UCNPs. The converted fluorescence stimulates AuNRs to generate heat through energy transfer. ROS production is induced by loading the photosensitizer Merocyanine 540 (MC540) in the mesoporous silica layer and is further enhanced through the surface plasma resonance effect of the AuNRs. This novel nanoplatform combines PTT and PDT in a single 808 nm near-infrared synergistic light therapy.
A large Turkish kindred with syndactyly type II (synpolydactyly). 1. Field investigation, clinical and pedigree data. (1995)

A very large Turkish family with syndactyly type II (synpolydactyly (SPD)) is described, which originated from and is mainly concentrated in the village of Derbent, Afyon. The kindred consists of 425 subjects over seven generations, of whom 182 are affected. It appears that a founder effect in this village has led to this extensive kindred. This condition is inherited as an autosomal dominant trait with variable expressivity and an estimated penetrance of 96%. Penetrance is different between the upper (96%) and lower (69.5%) extremities. No excess of affected males or females or other associated features were documented in this condition. Variations in the involvement of one or both hands, upper or lower extremities, bone and soft tissue, as well as variation in the affected subjects of two successive generations were documented. We also noted that metacarpal and metatarsal involvement and middle phalangeal hypoplasia of the feet are the consistent features of SPD and, therefore, should be considered as characteristic of this phenotype. We observed four different phenotypes in various branches of the Derbent kindred: (1) subjects presenting typical features of SPD; (2) subjects exhibiting both pre- and post-axial polydactyly simultaneously; (3) persons manifesting postaxial polydactyly type A; and (4) subjects born to two affected parents with severe hand and foot deformities that have not been previously described in any other SPD families (that is, homozygotes). A total of 27 affected offspring were born to two such affected parents, of whom seven are expected to be homozygous for the SPD gene. This group is presented in an accompanying paper in this issue of the Journal. A molecular study is currently under way to identify the chromosomal location of the defective gene.
ChemInform Abstract: Structure—Activity Relationships for Analogues of the Phenazine‐Based Dual Topoisomerase I/II Inhibitor XR11576. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
How I do it: Anterior pull-through tympanoplasty for anterior eardrum perforations (2016)

Conclusions This technique is offered as a convenient and reliable method for cases with anterior TM perforation and inadequate anterior remnant. Objectives Chronic otitis media surgery is one of the most common procedures in otology. Anterior tympanic membrane (TM) perforation with inadequate anterior remnant is associated with higher rates of graft failure. It was the goal of this series to evaluate the anatomical and functional outcomes of a modified underlay myringoplasty technique-the anterior pull-through method. Materials and methods In a retrospective clinical study, 13 patients with anterior TM perforations with inadequate anterior remnants underwent tympanoplasty with anterior pull-through technique. The anterior tip of the temporalis fascia was pulled through and secured in a short incision lateral to the anterior part of the annulus. Data on graft take rate, pre-operative, and post-operative hearing status were analyzed. Results A graft success rate of 84.6% (11 out of 13) was achieved, without lateralization, blunting, atelectasia, or epithelial pearls. The air-bone gap was 21.5 ± 6.8 dB before intervention and 11.75 ± 5.7 dB after surgery (p = 0.003).
An Overview of the Polymerization of Cyclosiloxanes (1983)

A review of the polymerization of cycloorganosiloxanes is provided. Cycloorganosiloxanes such as octamethyl cyclotetrasiloxane are the principal intermediate for the formation of high molecular weight polyorganosiloxane polymers. The ring opening reaction can be initiated through the use of suitable basic or acidic catalysts. The transformation of the cyclosiloxanes into linear chains is an equilibrium process characterized by a very low heat of polymerization. At equilibrium conversions one produces 12-15% of cyclic oligomers, which are predominantly but not exclusively the cyclic tetramer. Equations from the literature which define these equilibrium are reviewed. The principal mechanisms involved in the anionic ring opening polymerization via initiators such as potassium hydroxide are discussed. A host of other related initiator types have also been used, including the so-called transient catalysts which are based upon quaternary silanolates. The transient catalysts are so described since they rapidly decompose above 130°C to yield inactive byproducts. The anionic polymerization of siloxanes is relatively well understood and currently accepted mechanisms are presented. Cationic polymerization of organosiloxanes is also well known but is much less understood. In general, molecular weight vs. conversion curves for the two processes are considerably different and these aspects are reviewed. Molecular weight is often controlled by disiloxane or low molecular weight siloxane molecules terminated with triorganosiloxy groups. These materials (which are known as end blockers) control the molecular weight due to the fact that their silicon-oxygen bonds can exchange with and incorporate the growing chain. By contrast, the silicon-carbon bonds in such materials are incapable of reacting. Thus at equilibrium one incorporates most of the linear chains between the two triorganosiloxy terminals. Such a process is possible with either anionic or cationic intermediates. This approach has recently permitted the introduction of functional groups such as aminopropyl, carboxy propyl, epoxy propyl, etc. Such oligomers are interesting intermediates for novel segmented copolymers.
RNA-protein interaction mapping via MS2 or Cas13-based APEX targeting (2020)

Abstract RNA-protein interactions underlie a wide range of cellular processes. Improved methods are needed to systematically map RNA-protein interactions in living cells in an unbiased manner. Capitalizing on the ability of the engineered peroxidase APEX2 to identify protein interaction partners via proximity-dependent biotinylation, we used two approaches to target APEX2 to specific cellular RNAs. Both an MS2-MCP system and an engineered CRISPR-Cas13 system were able to deliver APEX2 to the human telomerase RNA hTR with high specificity. One-minute proximity biotinylation captured endogenous protein interaction partners of hTR, including more than a dozen proteins not previously linked to hTR. We validated the unexpected interaction between hTR and the N 6 -methyladenosine (m 6 A) demethylase ALKBH5. Further investigation showed that endogenous hTR is modified by m 6 A, which can be erased by ALKBH5, and that ALKBH5 influences both telomerase complex assembly and activity. These results highlight the ability of MS2- and Cas13-targeted APEX2 to identify novel RNA-protein interactions in living cells.
β‐ENDORPHIN: RADIORECEPTOR BINDING ASSAY (1980)

An assay system is described to measure the specific binding of β‐endorphin to opiate sites (receptors) in rat brain membrane preparations using the tritiated hormone as the primary ligand. By this assay procedure, the radioreceptor activity of β‐endorphin and synthetic analogs with various chain lengths has been determined. The results suggest that both NH 2 ‐ and COOH‐terminal sequences of the molecule are involved in the interaction of β‐endorphin with opiate receptors.
Double diastereoselective [3,3]-sigmatropic aza-Claisen rearrangements (2003)

Asymmetric [3,3]-sigmatropic aza-Claisen rearrangement of the (Z)-N-allyl-N,O-silylketene aminal of (3S,4E,alphaR)-1-benzyloxy-3-(N-propionyl-N-alpha-methylbenzylamino)hex-4-ene furnishes (2S,3R,4E,alphaR)-N-alpha-methylbenzyl-2,3-dimethyl-7-benzyloxyhept-4-enamide in > 92% d.e.; rearrangement of the diastereomeric (3R,4E,alphaR)-(Z)-N,O-silylketene aminal proceeds with low diastereoselectivity.
Serum Albumin: Early Prognostic Marker of Benefit for Immune Checkpoint Inhibitor Monotherapy But Not Chemoimmunotherapy (2022)

Pretreatment serum albumin and early albumin decrease in ICI monotherapy was significantly associated with OS in advanced NSCLC. Early albumin change, as a routine lab value tested in clinic, may be combined with established biomarkers to improve outcome predictions of ICI monotherapy. The underlying mechanism of the observed association between decreased albumin and ICI resistance warrants further investigation.
Continuous Spinal Anesthesia with a Microcatheter Technique (1990)

Received from the Department of Anesthesia, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts. Address correspondence to Dr. Hurley, Department of Anesthesia, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115. Accepted for publication July 19, 1989.