gebhart/patrepeval huggingface dataset:
Polygenic risk for anxiety influences anxiety comorbidity and suicidal behavior in bipolar disorder (2020)

Bipolar disorder is often comorbid with anxiety, which is itself associated with poorer clinical outcomes, including suicide. A better etiologic understanding of this comorbidity could inform diagnosis and treatment. The present study aims to test whether comorbid anxiety in bipolar disorder reflects shared genetic risk factors. We also sought to assess the contribution of genetic risk for anxiety to suicide attempts in bipolar disorder. Polygenic risk scores (PRS) were calculated from published genome-wide association studies of samples of controls and cases with anxiety (n = 83,566) or bipolar disorder (n = 51,710), then scored in independent target samples (total n = 3369) of individuals with bipolar disorder who reported or denied lifetime anxiety disorders or suicidal attempts in research interviews. Participants were recruited from clinical and nonclinical settings and genotyped for common genetic variants. The results show that polygenic risk for anxiety was associated with comorbid anxiety disorders and suicide attempts in bipolar disorder, while polygenic risk for bipolar disorder was not associated with any of these variables. Our findings point out that comorbid anxiety disorders in bipolar disorder reflect a dual burden of bipolar and anxiety-related genes; the latter may also contribute to suicide attempts. Clinical care that recognizes and addresses this dual burden may help improve outcomes in people living with comorbid bipolar and anxiety disorders.
Sequence homology of the fly proteins tropomyosin, arginine kinase and myosin light chain with known allergens in invertebrates (2015)

Due to the rapid growth of the world’s population and the increasing demand for food, there is an urgent need for alternative, more sustainable sources of protein. Insects have an important role in the diet in some societies and current initiatives are exploring the potential that insects have to offer for the production of food and feed. In this context, the safety implications of both producing and consuming insects are an important aspect to investigate. Here we present a bioinformatics analysis of proteomics data obtained for larvae of four different species of fly to assess the homology of tropomyosin, arginine kinase and myosin light chain with the crustacean orthologous proteins and other known allergenic proteins. The results indicate that the three proteins share homology with known allergens and therefore it is likely that they are also potential allergens. The implications in relation to mass rearing of flies are discussed.
Microstructural analysis of stir zone of Al alloy produced by friction stir spot welding (2008)

Friction stir spot welding (FSSW), which was recently developed as a spot joining technique, has been applied to a lap joint of Al alloy 6061 sheets, 1 mm in thickness, to clarify its microstructural features of the joint. A nugget shaped stir zone having finer grain size was observed around the exit hole of the probe. Crystallographic texture analyses using EBSD method suggested that the material flow occurred along the rotating direction of the FSSW tool in the wide region including the stir zone. In the periphery of the nugget shaped stir zone, which was characterised by finer grain size than the stir zone interior, no inclusions or precipitates were found on the SEM scale. A softened region was formed around the joint centre, which could be explained as resulting from dissolution and/or growth of the strengthening precipitates due to thermal cycle of FSSW.
Transplantation of Mature Photoreceptors in Rodents With Retinal Degeneration (2019)

This approach to restoration of sight in patients with photoreceptor degeneration can be rapidly advanced to clinical testing. In patients with central scotoma, autologous transplantation of the peripheral retina can be an option.
R&D of 3M Technologies towards the Realization of Exabit/s Optical Communications (2017)

Research efforts initiated by the EXAT Initiative are described to realize Exabit/s optical communications, utilizing the 3M technologies, i.e. multi-core fiber, multi-mode control and multi-level modulation.
Low-spin state of Fe in Fe-doped NiOOH electrocatalysts (2023)

Doping with Fe boosts the electrocatalytic performance of NiOOH for the oxygen evolution reaction (OER). To understand this effect, we have employed state-of-the-art electronic structure calculations and thermodynamic modeling. Our study reveals that at low concentrations Fe exists in a low-spin state. Only this spin state explains the large solubility limit of Fe and similarity of Fe-O and Ni-O bond lengths measured in the Fe-doped NiOOH phase. The low-spin state renders the surface Fe sites highly active for the OER. The low-to-high spin transition at the Fe concentration of ~ 25% is consistent with the experimentally determined solubility limit of Fe in NiOOH. The thermodynamic overpotentials computed for doped and pure materials, η = 0.42 V and 0.77 V, agree well with the measured values. Our results indicate a key role of the low-spin state of Fe for the OER activity of Fe-doped NiOOH electrocatalysts.
Intermolecular Interactions and Intramolecular Motions in Photomechanical Effect: Nonlinear Thermo- and Photomechanical Behaviors of Azobenzene-Functionalized Amide–Imide Block Copolymers (2021)

To discern multiple intertwined effects, a set of azobenzene-functionalized amide-imide block copolymers, azo(PA-<i>co</i>-PI)-<i>x</i>, where <i>x</i> is amide-block content, <i>viz</i>., [azoPA] = 25, 50, 75 mol %, was synthesized from 2,2-bis{4-[4-(4-aminophenyldiazenyl)phenoxy]phenyl}propane(azoBPA), 4,4'-oxydibenzoyl chloride (ODBC), and 4,4'-oxydiphthalic anhydride (OPDA). Including homopolymers (azoPA and azoPI), this series of amorphous azopolymers possesses a high glass-transition temperature (<i>T</i><sub>g</sub> > 210 °C) and a modulus (<i>E</i>' ∼ 1.23-2.50 GPa). Their photobending (ca. 23-90°) and photostress (ca. 250-380 kPa) were assessed in the form of cantilevers with a linearly polarized 445 nm light. Nonlinear composition/[azoPA] dependencies of the thermo- and photomechanical properties are correlated. As [azoPA] increases from 0 mol %; <i>T</i><sub>g</sub>, <i>E</i>', photostress, and photobending angle initially decrease to reach four separate minima for azo(PA-<i>co</i>-PI)-50; and then all increase with a higher [azoPA]. The trend considerations of film density, dynamic thermomechanical, Fourier transform infrared (FT-IR), and ultraviolet-visible (UV-vis) measurements implicate that (i) intermolecular association and intramolecular segmental mobility collectively influence the photomechanical outcomes and (ii) two types of hydrogen bonding (HB), namely, amide-amide [HB-AA] and amide-imide [HB-AI] coexist in azo(PA-<i>co</i>-PI)-<i>x</i> copolymers, with [HB-AI] being largely responsible for photomechanical outcomes of azo(PA-<i>co</i>-PI)-<i>x</i> with [azoPA] <40-50 mol %, and [HB-AA] for [azoPA] >40-50 mol %. We hypothesize that the "U-shaped" photomechanical effect apparently stems from the cooperative "unzipping" of H bonds in the [HB-AA]* excited state with H bonds in [HB-AI]* being stabilized by electrostatic interactions inherent in an excited intermolecular complex.
2030. Technology That Will Change the World. Von Rutger van Santen, Djan Khoe und Bram Vermeer. (2011)

Oxford University Press, 2010. 304 S., geb., 29.95 $.—ISBN 978-0195377170
Advances in Silicon Carbide Single Photon Detectors (2011)

We present overview of achieved results on 4H-SiC avalanche photodiodes (APDs) and arrays. Cost-effective solar-blind optical filter allows achieving high solar photon rejection ratio of more than 106 in combination with more than 40% single photon detection efficiency at 266nm. Three iterations of devices were fabricated and evaluated to compare their optical and electrical properties. Dark count rates and single photon detection efficiencies are the main characteristics compared for these three iterations of device designs.
Universal Control of Nuclear Spins Via Anisotropic Hyperfine Interactions (2007)

We show that nuclear spin subsystems can be completely controlled via microwave irradiation of resolved anisotropic hyperfine interactions with a nearby electron spin. Such indirect addressing of the nuclear spins via coupling to an electron allows us to create nuclear spin gates whose operational time is significantly faster than conventional direct addressing methods. We experimentally demonstrate the feasibility of this method on a solid-state ensemble system consisting of one electron and one nuclear spin.
Rate Analysis of Two-Receiver MISO Broadcast Channel With Finite Rate Feedback: A Rate-Splitting Approach (2015)

To enhance the multiplexing gain of two-receiver Multiple-Input-Single-Output Broadcast Channel with imperfect channel state information at the transmitter (CSIT), a class of Rate-Splitting (RS) approaches has been proposed recently, which divides one receiver's message into a common and a private part, and superposes the common message on top of Zero-Forcing precoded private messages. In this paper, with quantized CSIT, we study the ergodic sum rate of two schemes, namely RS-S and RS-ST, where the common message(s) are transmitted via a space and space-time design, respectively. Firstly, we upper-bound the sum rate loss incurred by each scheme relative to Zero-Forcing Beamforming (ZFBF) with perfect CSIT. Secondly, we show that, to maintain a constant sum rate loss, RS-S scheme enables a feedback overhead reduction over ZFBF with quantized CSIT. Such reduction scales logarithmically with the constant rate loss at high Signal-to-Noise-Ratio (SNR). We also find that, compared to RS-S scheme, RS-ST scheme offers a further feedback overhead reduction that scales with the discrepancy between the feedback overhead employed by the two receivers when there are alternating receiver-specific feedback qualities. Finally, simulation results show that both schemes offer a significant SNR gain over conventional single-user/multiuser mode switching when the feedback overhead is fixed.
Inclusiveπ0,η, and direct photon production at high transverse momentum inp+pandd+Aucollisions atsNN=200GeV (2010)

Made available in DSpace on 2015-06-26T12:36:28Z (GMT). No. of bitstreams: 1 2-s2.0-77954048309.pdf: 1441720 bytes, checksum: 7a3715c8a234cbb1ff1a8268504329dd (MD5) Previous issue date: 2010
Plasmonic components fabrication via nanoimprint (2009)

A review report on nanoimprinted plasmonic components is given. The fabrication of different metal-dielectric geometries and nanostructured surfaces that support either propagating or localized surface plasmon modes is discussed. The main characteristics and advantages of the nanoimprint technology for the fabrication of various plasmonic structures are outlined. The discussion of plasmonic waveguiding structures focuses on planar waveguides based on metal strips embedded into a dielectric and on profiled metal surfaces. Nanoimprint-based fabrication of two-dimensional nanostructured plasmonic surfaces for enhanced transmission studies and sensor applications is also discussed. Throughout the report, the main fabrication schemes are described, as well as the challenges facing future manufacturing of plasmonic components for device applications.
Thermal expansion of substrate may affect adhesion of Chinese hamster fibroblasts to surfaces during freezing (2018)

Despite success in cryopreservation of cells in suspension, cryopreservation of cells in monolayers is still challenging. One of the major problems is detachment of the cells from the substrate which occurs during cryopreservation. We hypothesized that this detachment may be due to a mismatch in the coefficient of linear thermal expansion αL between glass and the frozen cell layer which manifests as residual stress and stress relaxation. This mismatch results in a difference between the thermal expansion of ice and glass as they undergo temperature changes. Rinzl plastic coverslips were selected as a possible substitute for glass because Rinzl has an αL (60 × 10-6/K) similar to that of ice (51 × 10-6/K) whereas glass has a much lower αL (5 × 10-6/K). V79-4 Chinese hamster fibroblasts were cultured on both glass and Rinzl coverslips until confluent and the area of coverage was measured before and after freezing at -9 °C. The glass coverslips showed significant loss of cells (coverage = 77.9 ± 8.0%) compared with Rinzl (coverage = 97.9 ± 1.4%). We concluded that Rinzl coverslips may improve cell attachment in future monolayer cryopreservation experiments.
Cathode dependence of the open-circuit voltage of polymer:fullerene bulk heterojunction solar cells (2003)

The open-circuit voltage (VOC) of bulk-heterojunction solar cells based on [6,6]-phenyl C61-butyric acid methyl ester (PCBM) as electron acceptor and poly[2-methoxy-5(3′,7′-dimethyloctyloxy)-p-phenylene vinylene] (OC1C10-PPV) as an electron donor has been investigated. In contrast to the present understanding, it is now demonstrated that for non-ohmic contacts the experimental VOC is determined by the work function difference of the electrodes. A total variation of more than 0.5 V of the VOC was observed by variation of the negative electrode (cathode) work function. For ohmic contacts the VOC is governed by the LUMO and HOMO levels of the acceptor and donor, respectively, which pin the Fermi levels of the cathode and anode. The band bending created by accumulated charges at an ohmic contact produce a considerable loss in VOC of 0.2 V at room temperature. The experimentally observed voltage loss in VOC of 0.38 V due to the presence of ohmic contacts at both interfaces strongly limits the maximum open-circuit voltage of OC1C10-PPV/PCBM solar cells.
Thoracic actinomycosis: CT findings. (1998)

Findings of chronic segmental air-space consolidation that contained low-attenuation areas with peripheral enhancement or adjacent pleural thickening at CT were suggestive of thoracic actinomycosis.
Quantum random number generators (2023)

Random number generators include a thermal optical source and detector configured to produce random numbers based on quantum-optical intensity fluctuations. An optical flux is detected, and signals proportional to optical intensity and a delayed optical intensity are combined. The combined signals can be electrical signals or optical signals, and the optical source is selected so as to have low coherence over a predetermined range of delay times. Balanced optical detectors can be used to reduce common mode noise, and in some examples, the optical flux is directed to only one of a pair of balanced detectors.
Practical Channel Interpolation for OFDMA (2006)

This paper addresses piecewise frequency domain interpolation for OFDMA channels when raw estimates are given on a sparse grid of pilot carriers in a fraction of the spectrum only. Starting from the optimal linear interpolation which needs a-priori information on the power delay profile and the SNR, we develop robust suboptimal schemes that do not require such information. One scheme is based on singular value decomposition and it allows the estimation of the SNR. In practice, however, it is difficult to obtain the required information on the power delay profile. To ensure robustness of the filter to mismatched channel parameters, a favorable assumption of the power delay profile is suggested for the filter design. It is further shown that a full-spectrum interpolation assembled from mul- tiple piecewise interpolation results has a dramatically reduced complexity which makes it suitable for real-time implementation. In this paper, we revisit the problem of linear channel inter- polation for OFDMA. We derive a complexity reduced interpo- lation method based on truncated singular value decomposition (TSVD) and compare it with the LMMSE interpolation. Our major contribution is a new method for estimation of the SNR from the sparse pilot grid. The channel decay time, coarsely describing the power delay profile (PDP), is assumed as half the length of the guard interval. Using both parameters for the LMMSE estimator we observe the smallest performance degradation compared to the ideal LMMSE estimator. More- over, the complexity is assessed and the proposed method is shown to be feasible in real-time. The paper is organized as follows: In sections II and III, the notation and the channel model are introduced. The interpo- lation techniques are analyzed in section IV. The complexity is considered in section V. Numerical results are described in section VI.
Practical Implementation Considerations in the Detection of GPS Satellite Signal Failure (2000)

The infamous undetected failure of GP S Satellite PRN 19
instigated studies investigating the ground network
detection of satellite signal anomalies and the placement
of design constraints on aviation GPS receivers. These
anomalies cause the distortion of the GPS C/A code
autocorrelation function that causes differences in code
tracking errors in differently-designed receivers. It was
first thought that the ground network implementation for
detecting these anomalies would be quite complex,
especially considering the false detection and missed
detection requirements associated with the continuity and
integrity requirements placed upon these ground facilities.
However, extensive studies and design efforts performed
over the past few months have resulted in relatively
practical implementations. This is because practical
implementation considerations were emphasized and an
effort was made to understand the requirements. This
paper will lead the reader through that implementation
process.
QEC: A Quantum Entropy Chip and Its Applications (2020)

Quantum phenomena cannot be predicted by the uncertainty principle. As a quantum phenomenon, radioactive decay has been used as an entropy source to generate random numbers. In this article, we present the design and development of an innovative quantum entropy chip (QEC) that produces analog random pulses when emitted alpha particles resulted from radioactive isotope (americium-241) decay hit the sensor. The analog pulse generated by a QEC can be digitized into random numbers by an entropy extractor. The QEC provides security foundation for device authentication as well as a quantum random number generator (QRNG), especially suited for the Internet of Things (IoT) devices due to its small size. We have successfully designed and fabricated the QEC as a wafer for supporting a system-on-chip (SoC) Internet Protocol (IP) so that the QEC can be embedded into a microcontroller unit (MCU) or central processing unit (CPU). In addition, we built a stochastic model to estimate the entropy of the quantum source and evaluated statistical randomness and robustness against temperature, voltage variations, aging effects, and physical attacks. Finally, we demonstrate various applications using the QEC such as side-channel-resistant primitives and device authentication.
System synthesis of synchronous multimedia applications (1999)

Modern system design is being increasingly driven by applications such as multimedia and wireless sensing and communications, which all have intrinsic quality of service (QoS) requirements, such as throughput, error-rate, and resolution. One of the most crucial QoS guarantees that the system has to provide is the timing constraints among the interacting media (synchronization) and within each media (latency). We have developed the first framework for systems design with timing QoS guarantees, latency and synchronization. In particular we address how to design system-on-chip with minimal silicon area to meet timing constraints. We propose the two-phase design methodology. In the first phase, we select an architecture which facilitates the needs of synchronous low latency applications well. In the second phase, for a given processor configuration, we use our new scheduler in such a way that storage requirements are minimized. We have developed scheduling algorithms that solve the problem optimally for a-priori specified applications. The algorithms have been implemented and their effectiveness demonstrated on a set of simulated MPEG streams from popular movies.
Relationship of the Musculocutaneous Nerve and Its Twigs to the Coracoid Process: An Operative Exposure (2020)

As the Latarjet procedure is an emerging technique, it is essential to be aware of the anatomic structures and the relation between different neural structures to anatomic points of reference. Therefore, the results of this study add significant information for a safe surgical procedure for the majority of patients suffering from shoulder instability.
Evaluation of exposure levels generated by cellular systems: methodology and results (2002)

During the past years, the number of antenna installations has considerably increased mainly as a consequence of the great diffusion of cellular systems. While the emissions of mobile terminals principally concern cellular system users, the exposure due to base stations (BSs) is permanent and spread over the entire territory. In this paper, a flexible approach for the evaluation of exposure levels generated by cellular systems BSs is proposed. Both a conceptual method for the evaluation of the overall exposure level and a site specific method for the computation of the field in the surroundings of BS antennas are proposed. This last method is based on a combination of three different propagation models which enable an accurate evaluation of the field both close to the antenna and farther off. The validity of the approach is checked by comparison with measurements in single-antenna and multiantenna cases.
HYSTERICAL AMBLYOPIA (1975)

Six hysterical amblyopes and six controls, matched for age and sex, were evaluated as to acuity, color vision, visual fields, dark adaptometry and visual evoked responses (VER). Although the hysterical amblyopes all showed reduced acuity and constricted visual fields, no statistically significant differences were found for the dark adaptation final thresholds when compared to the control group. VERs to stimuli which were varied with respect to brightness, color, frequency and pattern, did not statistically differentiate hysterical amblyopes from the control group. The results appear to indicate the intactness of the visual pathways up to and including cortical area 1 7 in hysterical amblyopia.
Sample pooling: burden or solution? (2021)

The theory of pool testing is well understood and numerous successful examples from the past are available. Operationalization of pool testing requires sophisticated processes that can be adapted to the local medical circumstances. Special attention needs to be paid to sample collection, sample pooling, and strategies to avoid re-sampling.
Study of cereals flows at local scales: Examples in the Rhône-Alpes région, the Isère département and the SCOT de Grenoble (2012)

International audience