gebhart/patrepeval huggingface dataset:
Executing task graphs using work-stealing (2010)

NABBIT is a work-stealing library for execution of task graphs with arbitrary dependencies which is implemented as a library for the multithreaded programming language Cilk++. We prove that Nabbit executes static task graphs in parallel in time which is asymptotically optimal for graphs whose nodes have constant in-degree and out-degree. To evaluate the performance of Nabbit, we implemented a dynamic program representing the Smith-Waterman algorithm, an irregular dynamic program on a two-dimensional grid. Our experiments indicate that when task-graph nodes are mapped to reasonably sized blocks, Nabbit exhibits low overhead and scales as well as or better than other scheduling strategies. The Nabbit implementation that solves the dynamic program using a task graph even manages in some cases to outperform a divide-and-conquer implementation for directly solving the same dynamic program. Finally, we extend both the Nabbit implementation and the completion-time bounds to handle dynamic task graphs, that is, graphs whose nodes and edges are created on the fly at runtime.
Water-soluble complexes of tertiary phosphines and rhodium(I) as homogeneous catalysts (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTWater-soluble complexes of tertiary phosphines and rhodium(I) as homogeneous catalystsRalph G. Nuzzo, David Feitler, and George M. WhitesidesCite this: J. Am. Chem. Soc. 1979, 101, 13, 3683–3685Publication Date (Print):June 1, 1979Publication History Published online1 May 2002Published inissue 1 June 1979https://pubs.acs.org/doi/10.1021/ja00507a056https://doi.org/10.1021/ja00507a056research-articleACS PublicationsRequest reuse permissionsArticle Views277Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Optimal modeling for complex system design (1998)

Primary cardiac tumors are extremely rare and cardiac hemangiomas comprise less than 3% of them. Presentation of such disease with recurrent pericardial effusion is even rarer. Our patient is known case of myelodysplastic syndrome and up to our knowledge there are no reported case in which cardiac hemangioma was diagnosed in a patient with myelodysplastic syndrome. This 64 years male patient presented to our department with recurrent pericardial effusion, diagnosis was a query after extensive work he was found to suffer from a cardiac tumor based on the pulmonary artery and right ventricle. We performed surgery for him on cardiopulmonary bypass and did complete resection of the mass for him and result of biopsy showed mixed hemangioma. Recurrent pericardial effusion is most commonly a sign of a malignancy. Even with advancement of medical technology diagnoses of cardiac hemangiomas are still difficult. Treatment and definitive diagnosis is still complete surgical resection and histopathological examination.
A Hybrid Downlink NOMA With OFDM and OFDM-IM for Beyond 5G Wireless Networks (2020)

In this paper, a hybrid power domain non-orthogonal multiple accessing (NOMA) scheme by the superposition of orthogonal frequency division multiple accessing (OFDM) and index modulated OFDM (OFDM-IM) technologies is presented and named IM-NOMA. It is shown via both computer-based simulations and mathematical analysis that IM-NOMA outperforms the classical OFDM-NOMA in terms of bit error rate (BER) under a total power constraint and achievable sum rate. The system performance of IM-NOMA not only depends on the power difference between the overlapping users but also on features of the OFDM-IM signal. Hence, this scheme is robust against possible catastrophic error performance in case similar power is assigned to the users.
Automated colour identification in melanocytic lesions (2015)

Colour information plays an important role in classifying skin lesion. However, colour identification by dermatologists can be very subjective, leading to cases of misdiagnosis. Therefore, a computer-assisted system for quantitative colour identification is highly desirable for dermatologists to use. Although numerous colour detection systems have been developed, few studies have focused on imitating the human visual perception of colours in melanoma application. In this paper we propose a new methodology based on QuadTree decomposition technique for automatic colour identification in dermoscopy images. Our approach mimics the human perception of lesion colours. The proposed method is trained on a set of 47 images from NIH dataset and applied to a test set of 190 skin lesions obtained from PH2 dataset. The results of our proposed method are compared with a recently reported colour identification method using the same dataset. The effectiveness of our method in detecting colours in dermoscopy images is vindicated by obtaining approximately 93% accuracy when the CIELab1 colour space is used.
<title>500-Mb/s 32-channel CMOS VCSEL driver with built-in self-test and clock generation circuitry</title> (1999)

This paper describes the design, electrical nd optical test results for a 500Mb/s, 32-channel VCSEL driver ICs with built-in self-test and clock generation circuitry. The circuit design and silicon parts are available to the research community through the Consortium for Optical and Optoelectronic Technologies in Computing and the Optoelectronics Industry Association. This device is specifically targeted at users building VCSEL-based smart photonic system demonstrators.
N9 Neuraminidase Complexes with Antibodies NC41 and NC10: Empirical Free Energy Calculations Capture Specificity Trends Observed with Mutant Binding Data (1994)

X-ray crystallographic coordinates of influenza virus N9 neuraminidase complexed with monoclonal antibodies NC41 and NC10 [Tulip et al. (1992) J. Mol. Biol. 227, 122-148] served as a starting point for calculations aimed at estimating free energy changes (delta G) of complex formation between the two antibodies and the neuraminidase. Using an empirical function incorporating hydrophobic, electrostatic, and conformational entropy effects, we estimated contributions individual neuraminidase residues make to complex formation (delta G(residue)) and compared the calculated values to experimentally measured differences in antibody binding between the wild-type and mutated neuraminidases [Nuss et al. (1993) Proteins 15, 121-132; calculations done without prior knowledge of the experimental data]. A good correspondence was found between the calculated delta G(residue) values and the mutant binding data in that side chains with large calculated delta G contributions (delta G(residue) < -1 kcal/mol) lie at sites of mutation which cause a marked reduction in antibody binding, and side chains for which delta G(residue) > -1 kcal/mol are sites at which a mutation does not have a marked effect on binding. Because most of the delta G(residue) < -1 kcal/mol side chains also make hydrogen bonds/salt bridges with the antibody, the correspondence of the effect of antibody binding with these electrostatic interactions (18 out of 27 for NC41 and, tentatively, 5 out of 7 for NC10) is about as good as that with predicted energetic residues. All the delta G(residue) < -1 kcal/mol neuraminidase side chains cluster around the most protruding surface regions and are thus spread over different epitope segments. Surprisingly, different residues were found to make the most critical contributions to the NC41 and NC10 complex stabilities despite the fact that the NC41 and NC10 antigenic epitopes overlap, having approximately 70% of surface residues in common. It is thus possible, for two different antibodies, to recognize the same protein surface in strikingly different ways. As only a fraction of the neuraminidase residues appear to make large contributions to antibody binding, the results also support the hypothesis of a "functional" epitope in antigen-antibody interactions. Positive trends between both backbone rigidity and residue accessibility in the complexed state, and contributions of these residues to binding, were also observed for the NC41 complex.
Improvements to the Tunnel Diode Oscillator technique for high\n frequencies and pulsed magnetic fields with digital acquisition (2010)

We discuss improvements to the short-term performance of tunnel diode\noscillator transducers with an emphasis on frequencies from 30 MHz to 1.2 GHz\nusing LC type tank circuits. We specifically consider the TDO in pulsed high\nmagnetic fields with fast digital acquisition. Since overdriven oscillators are\nnecessary in pulsed fields to maintain oscillations, we examine the circuit\nusing SPICE simulation during the design process and to gain insight into its\nbehavior. We also discuss a numerical technique for demodulating the\noscillations into frequency and amplitude.\n
Protein kinase activity associated with the purified rat hepatic glucocorticoid receptor. (1985)

The Mr 94,000 steroid binding component of rat hepatic glucocorticoid receptor purified 5000-fold under-goes calcium-stimulated phosphorylation in vitro by [gamma-32P]ATP. Exogenous histones can be phosphorylated by this preparation without calcium. Calmodulin did not stimulate phosphorylation of the glucocorticoid receptor beyond that obtained with calcium alone. Although the specific calmodulin inhibitor calmidazolium had no effect, trifluoperazine and chlorpromazine, nonspecific calmodulin inhibitors, abolished the calcium-dependent phosphorylation of receptor. EGTA blocks the effect of calcium; magnesium cannot substitute for calcium. Cyclic nucleotides (cAMP or cGMP) do not stimulate phosphorylation of the receptor in the absence of calcium. Phosphorylation of the glucocorticoid receptor is steroid dependent. Triamcinolone acetonide elicited activation and phosphorylation of receptor in the presence of calcium, whereas the antagonists progesterone, cortexolone, and beta-lapachone did not. Sodium molybdate, which blocks the thermal activation step, inhibits phosphorylation of the receptor. The activated form of the glucocorticoid receptor is required for phosphorylation to occur. The ATP analogues 8-azido-ATP or fluorosulfonylbenzoyl adenosine, inhibit phosphorylation of the Mr 94,000 component, implying the presence of an ATP binding site inherent to the receptor.
Identification of New Functional Regions in Hepatitis C Virus Envelope Glycoprotein E2 (2010)

Little is known about the structure of the envelope glycoproteins of hepatitis C virus (HCV). To identify new regions essential for the function of these glycoproteins, we generated HCV pseudoparticles (HCVpp) containing HCV envelope glycoproteins, E1 and E2, from different genotypes in order to detect intergenotypic incompatibilities between these two proteins. Several genotype combinations were nonfunctional for HCV entry. Of interest, a combination of E1 from genotype 2a and E2 from genotype 1a was nonfunctional in the HCVpp system. We therefore used this nonfunctional complex and the recently described structural model of E2 to identify new functional regions in E2 by exchanging protein regions between these two genotypes. The functionality of these chimeric envelope proteins in the HCVpp system and/or the cell-cultured infectious virus (HCVcc) was analyzed. We showed that the intergenotypic variable region (IgVR), hypervariable region 2 (HVR2), and another segment in domain II play a role in E1E2 assembly. We also demonstrated intradomain interactions within domain I. Importantly, we also identified a segment (amino acids [aa] 705 to 715 [segment 705-715]) in the stem region of E2, which is essential for HCVcc entry. Circular dichroism and nuclear magnetic resonance structural analyses of the synthetic peptide E2-SC containing this segment revealed the presence of a central amphipathic helix, which likely folds upon membrane binding. Due to its location in the stem region, segment 705-715 is likely involved in the reorganization of the glycoprotein complexes taking place during the fusion process. In conclusion, our study highlights new functional and structural regions in HCV envelope glycoprotein E2.
Visual task characterization for automated visual discourse synthesis (1998)

To develop a comprehensive and systematic approach to the automated design of visual discourse, we introduce a visual task taxonomy that interfaces high-level presentation intents with low-level visual techniques. In our approach, visual tasks describe presentation intents through their visual accomplishments, and suggest desired visual techniques through their visual implications. Therefore, we can characterize visual tasks by their visual accomplishments and implications. Through this characterization, visual tasks can guide the visual discourse synthesis process by specifying what presentation intents can be achieved and how to achieve them.
Supplemental Table S2 from Histone Deacetylase HDAC8 Promotes Insulin Resistance and β-Catenin Activation in NAFLD-Associated Hepatocellular Carcinoma (2023)

&lt;p&gt;Clinicopathological information of the NAFLD-associated HCC patients.&lt;/p&gt;
Low Complexity Metric for Joint MLD in Overloaded MIMO System (2015)

This paper presents a low complexity metric for joint maximum-likelihood detection (MLD) in overloaded multiple-input multiple-output (MIMO)-orthogonal frequency division multiplexing (OFDM) systems. In overloaded MIMO systems, a nonlinear detection scheme such as MLD combined with error correction coding achieves superior performance than that of a single signal stream with higher order modulation. However, MLD demands large computational complexity because of multiplications in the selection of candidate signal points. Thus, a Manhattan metric has been used to reduce the complexity. Nevertheless, it is not accurate and causes performance degradation in overloaded MIMO systems. Thus, this paper proposes a new metric that is calculated with summations and bit shifts. New numerical results obtained through computer simulation show that the proposed metric improves bit error rate (BER) performance more than 0.2dB at the BER of 10^(-4) in comparison with a Manhattan metric.
A SelB/EF-Tu/aIF2γ-like protein from Methanosarcina mazei in the GTP-bound form binds cysteinyl-tRNACys (2015)

The putative translation elongation factor Mbar_A0971 from the methanogenic archaeon Methanosarcina barkeri was proposed to be the pyrrolysine-specific paralogue of EF-Tu ("EF-Pyl"). In the present study, the crystal structures of its homologue from Methanosarcina mazei (MM1309) were determined in the GMPPNP-bound, GDP-bound, and apo forms, by the single-wavelength anomalous dispersion phasing method. The three MM1309 structures are quite similar (r.m.s.d. < 0.1 Å). The three domains, corresponding to domains 1, 2, and 3 of EF-Tu/SelB/aIF2γ, are packed against one another to form a closed architecture. The MM1309 structures resemble those of bacterial/archaeal SelB, bacterial EF-Tu in the GTP-bound form, and archaeal initiation factor aIF2γ, in this order. The GMPPNP and GDP molecules are visible in their co-crystal structures. Isothermal titration calorimetry measurements of MM1309·GTP·Mg(2+), MM1309·GDP·Mg(2+), and MM1309·GMPPNP·Mg(2+) provided dissociation constants of 0.43, 26.2, and 222.2 μM, respectively. Therefore, the affinities of MM1309 for GTP and GDP are similar to those of SelB rather than those of EF-Tu. Furthermore, the switch I and II regions of MM1309 are involved in domain-domain interactions, rather than nucleotide binding. The putative binding pocket for the aminoacyl moiety on MM1309 is too small to accommodate the pyrrolysyl moiety, based on a comparison of the present MM1309 structures with that of the EF-Tu·GMPPNP·aminoacyl-tRNA ternary complex. A hydrolysis protection assay revealed that MM1309 binds cysteinyl (Cys)-tRNA(Cys) and protects the aminoacyl bond from non-enzymatic hydrolysis. Therefore, we propose that MM1309 functions as either a guardian protein that protects the Cys moiety from oxidation or an alternative translation factor for Cys-tRNA(Cys).
Microstructural Evolution in Transition-metal-oxide Cathode Materials for Lithium-Ion Batteries (2016)

Layered transition metal oxides are promising materials for high-energy lithium-ion battery cathodes. These materials offer high capacity and rate capability, good safety, and relatively low cost compared to many alternative materials Mixed oxides such as NCA (LiNi 0.8 Co 0.15 Al 0.05 O 2 ) exhibit high capacity but suffer from a significant capacity fade with cycling The composition of alternatives such as NMC (LiNi 1-x-y Mn x Co y O 2 ) can be tuned to show less capacity fade, but generally at the cost of lower capacity. Consequently, there is great interest in cycling these materials to higher potentials for more energy, but then cycling performance decreases.
Four-year polymer biocompatibility and vascular healing profile of a novel ultrahigh molecular weight amorphous PLLA bioresorbable vascular scaffold: an OCT study in healthy porcine coronary arteries (2016)

At four years, the novel PLLA BRS elicited a vascular healing response comparable to BMS in healthy pigs. Expansive vascular remodelling was evident only in the BRS group, a biological phenomenon that appears to be independent of the presence of antiproliferative drugs.
Dominant Effect of Support Wettability on the Reaction Pathway for Catalytic Wet Air Oxidation over Pt and Ru Nanoparticle Catalysts (2018)

Support wettability can play a key role in directing the activation of oxygen during catalytic wet air oxidation over nanoparticle catalysts. When the nanoparticles are composed of metallic Pt, the optimum support is hydrophobic, but when they are ionic Ru, a hydrophilic support is more effective. This reversal in support effect is consistent with two distinct surface pathways: one in which gas-phase O2 is directly adsorbed on the Pt0 surface and the other in which dissolved O2 is activated on RuO2 immersed in the contaminated aqueous phase. The known effects of ceria on these precious metal catalysts are of secondary importance to support wettability.
Unprecedented Homoleptic Bis‐Tridentate Iridium(III) Phosphors: Facile, Scaled‐Up Production, and Superior Chemical Stability (2017)

Bis‐tridentate Ir(III) metal complexes are expected to show great potential in organic light‐emitting diode (OLED) applications due to the anticipated, superb chemical and photochemical stability. Unfortunately, their exploitation has long been hampered by lack of adequate methodology and with inferior synthetic yields. This hurdle can be overcome by design of the first homoleptic, bis‐tridentate Ir(III) complex [Ir(pzpyph)(pz H pyph)] ( 1 ), for which the abbreviation (pzpyph)H (or pz H pyph) stands for the parent 2‐pyrazolyl‐6‐phenyl pyridine chelate. After that, methylation and double methylation of 1 afford the charge‐neutral Ir(III) complex [Ir(pzpyph)(pz Me pyph)] ( 2 ) and cationic complex [Ir(pz Me pyph) 2 ][PF 6 ] ( 3 ), while deprotonation of 1 gives formation of anionic [Ir(pzpyph) 2 ][NBu 4 ] ( 4 ), all in high yields. These bis‐tridentate Ir(III) complexes 2 – 4 are highly emitted in solution and solid states, while the charge‐neutral 2 and corresponding t ‐butyl substituted derivative [Ir(pzpy Bu ph)(pz Me py Bu ph)] ( 5 ) exhibit superior photostability versus the tris‐bidentate references [Ir(ppy) 2 (acac)] and [Ir(ppy) 3 ] in toluene under argon, making them ideal OLED emitters. For the track record, phosphor 5 gives very small efficiency roll‐off and excellent overall efficiencies of 20.7%, 66.8 cd A −1 , and 52.8 lm W −1 at high brightness of 1000 cd m −2 . These results are expected to inspire further studies on the bis‐tridentate Ir(III) complexes, which are judged to be more stable than their tris‐bidentate counterparts from the entropic point of view.
Membrane biochemistry of the ouabain-resistant potassium transport system. (1987)

A 6.5-kilobase fragment of genomic DNA from mutant mouse cells under ouabain selection pressure conferred ouabain resistance when transfected into ouabain-sensitive CV1 green monkey fibroblasts. Ouabain resistance was induced in the presence of 10 microM ouabain. Amiloride (500 microM) completely blocked ouabain-insensitive 86Rb+ uptake into these cells. Plasma membranes from these cells demonstrated little sodium-dependent adenosine triphosphatase (ATPase) activity but had potassium-dependent and ouabain-resistant p-nitrophenylphosphatase activity. Like Na+,K+-ATPase this activity was vanadate- and sodium-inhibitable. Also, like the Na+,K+-ATPase, sodium inhibition of the p-nitrophenylphosphatase was reversed by 10 microM adenosine 5'-triphosphate.
Search for pair production of vector-like quarks in the bWb‾W channel from proton–proton collisions at s=13TeV (2018)

A search is presented for the production of vector-like quark pairs, or , with electric charge of 2/3 (T) or (Y), in proton-proton collisions at . The data were collected by the CMS experiment at the LHC in 2016 and correspond to an integrated luminosity of . The T and Y quarks are assumed to decay exclusively to a W boson and a b quark. The search is based on events with a single isolated electron or muon, large missing transverse momentum, and at least four jets with large transverse momenta. In the search, a kinematic reconstruction of the final state observables is performed, which would permit a signal to be detected as a narrow mass peak (7% resolution). The observed number of events is consistent with the standard model prediction. Assuming strong pair production of the vector-like quarks and a 100% branching fraction to , a lower limit of 1295 GeV at 95% confidence level is set on the T and Y quark masses.
ChemInform Abstract: Synthesis and SAR of Adatanserin: Novel Adamantyl Aryl‐ and Heteroarylpiperazines with Dual Serotonin 5‐HT1A and 5‐HT2 Activity as Potential Anxiolytic and Antidepressant Agents. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.