gebhart/patrepeval huggingface dataset:
Performance Benefit of Virtual Path Tunneling for Control and Management Flows in the Broadband ATM Network (1999)

In this paper, we analyze the performance benefits of broadband ATM networks when the call control and management flows are separated from user data flows. The virtual path tunneling concept for control and management flows are applied to the same physical ATM networks. The behaviors of channel throughput and transfer delay are analyzed. It results that the proposed virtual short-cut paths can maintain the network being stable with acceptable bandwidth. They are very useful to provide the stable control and management capabilities for Internet and mobile applications in the broadband ATM networks. In our numerical results, the effective throughputs of the proposed virtual short-cut channel are about three times than those of end-to-end user data channels with hop distances of 10, and about two times than those with hop distance of 5 when the link blocking probability increases to 0.1. It concludes that the effective channel bandwidth are greatly reduced down while physical links are not stable and user traffic flows are occasionally overflowed.
CWDM based HDMI cable using passively aligned optical interconnect modules (2011)

Coarse WDM based short-reach OSA modules were demonstrated by taking advantage of a passive alignment scheme. They were used to build an optical HDMI cable, affording to efficiently deliver 1080p HDMI video/audio data.
Body sway predicts romantic interest in speed dating (2019)

Social bonding is fundamental to human society, and romantic interest involves an important type of bonding. Speed dating research paradigms offer both high external validity and experimental control for studying romantic interest in real-world settings. While previous studies focused on the effect of social and personality factors on romantic interest, the role of non-verbal interaction has been little studied in initial romantic interest, despite being commonly viewed as a crucial factor. The present study investigated whether romantic interest can be predicted by non-verbal dyadic interactive body sway, and enhanced by movement-promoting (‘groovy’) background music. Participants’ body sway trajectories were recorded during speed dating. Directional (predictive) body sway coupling, but not body sway similarity, predicted interest in a long-term relationship above and beyond rated physical attractiveness. In addition, presence of groovy background music promoted interest in meeting a dating partner again. Overall, we demonstrate that romantic interest is reflected by non-verbal body sway in dyads in a real-world dating setting. This novel approach could potentially be applied to investigate non-verbal aspects of social bonding in other dynamic interpersonal interactions such as between infants and parents and in non-verbal populations including those with communication disorders.
Impact of clinicopathological variables on mTOR Pathway activation in primary renal cell carcinoma (RCC) and matched metastases (2010)

Kutikov, Alexander MD; Piotrowski, Zachary MD; Egleston, Brian L. PhD; Huang, Min MD; Al-Saleem, Tahseen MD; Uzzo, Robert G. MD Author Information
A proposal for routing-based timing-driven scan chain ordering (2004)

Scan chain insertion can have large impact on routability, wirelength and timing. We propose a routing-driven and timing-aware methodology for scan insertion with minimum wirelength. We take into account timing slacks at all sinks that are affected by scan insertion, to achieve a scan chain ordering that meets timing and has smallest wirelength. For the case where sink timing is not met, we also propose a buffer insertion methodology with minimum wirelength objective. The key contribution of this paper is a method to compute a timing-driven incremental connection suited to scan insertion; this has possible applications in general incremental routing.
Selection of peptide entry motifs by bacterial surface display (2002)

Surface display technologies have been established previously to select peptides and polypeptides that interact with purified immobilized ligands. In the present study, we designed and implemented a surface display-based technique to identify novel peptide motifs that mediate entry into eukaryotic cells. An Escherichia coli library expressing surface-displayed peptides was combined with eukaryotic cells and the gentamicin protection assay was performed to select recombinant E. coli, which were internalized into eukaryotic cells by virtue of the displayed peptides. To establish the proof of principle of this approach, the fibronectin-binding motifs of the fibronectin-binding protein A of Staphylococcus aureus were inserted into the E. coli FhuA protein. Surface expression of the fusion proteins was demonstrated by functional assays and by FACS analysis. The fibronectin-binding motifs were shown to mediate entry of the bacteria into non-phagocytic eukaryotic cells and brought about the preferential selection of these bacteria over E. coli expressing parental FhuA, with an enrichment of 100000-fold. Four entry sequences were selected and identified using an S. aureus library of peptides displayed in the FhuA protein on the surface of E. coli. These sequences included novel entry motifs as well as integrin-binding Arg-Gly-Asp (RGD) motifs and promoted a high degree of bacterial entry. Bacterial surface display is thus a powerful tool to effectively select and identify entry peptide motifs.
Site-Specific Knowledge and Interference Measurement for Improving Frequency Allocations in Wireless Networks (2008)

We present new frequency allocation schemes for wireless networks and show that they outperform all other published work. Two categories of schemes are presented: 1) those purely based on measurements and 2) those that use site-specific knowledge, which refers to knowledge of building layouts, the locations and electrical properties of access points (APs), users, and physical objects. In our site-specific knowledge-based algorithms, a central network controller communicates with all APs and has site-specific knowledge so that it can <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">a</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">priori</i> predict the received power from any transmitter to any receiver. Optimal frequency assignments are based on predicted powers to minimize interference and maximize throughput. In our measurement-based algorithms, clients periodically report <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">in</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">situ</i> interference measurements to their associated APs; then, the APs' frequency allocations are adjusted based on the reported measurements. Unlike other work, we minimize interference seen by both <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">users</i> and <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">APs</i> , use a <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">physical</i> model rather than a <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">binary</i> model for interference, and mitigate the impact of rogue interference. Our algorithms consistently yield high throughput gains, irrespective of the network topology, AP activity level, number of APs, rogue interferers, and available channels. Our algorithms outperform the best published work by 18.5%, 97.6%, and 1180% for median, 25th percentile, and 15th percentile user throughputs, respectively.
Bisphosphonate targeting to specific skeletal sites in mice with whole body vibration (2010)

The prospects of a combined targeting, and monitoring of the drug binding to specific skeletal sites by noninvasive means is determined. Site‐selective skeletal targeting of bisphosphonates, if feasible, is ideal to overcome drug‐related side effects. We utilized near‐infrared (NIR) fluorescence imaging to monitor the noninvasive delivery of NIR dye conjugate bisphosphonate, and the role of whole body vibration (WBV) to aid drug targeting. Vibration loading, utilizing whole body vibration (WBV) was performed on twelve mice by subjecting them to vibration frequency of 35 Hz for fifteen min (5–10 times/week) duration. Alendronate was conjugated to near‐infrared tricarbocyanine, cyclic enamine‐functionalized dye, and was injected intravenously after 21‐day exercise regime; the mice were imaged using a commercially available imaging system, KODAK in‐Vivo Multispectral FX system. Besides several specific targeting sites, NIR‐alendronate probe binding to the lumbar L6 vertebrae was explicitly observed, resultant of direct high‐frequency WBV stimulation. The targeted drug binding in response to the vibratory protocol provides hope in the development of whole body vibration (WBV) as a bisphosphonate‐therapeutic aid, and to develop strategies in reducing the drug dosage in osteoporosis treatment.
Antibody production in mice. V. The suppressive effect of anti-carrier antibodies on cellular cooperation in the induction of secondary anti-hapten antibody responses. (1973)

Cooperative induction of secondary anti-hapten antibody responses was studied by using non-cross-reactive carrier proteins, bacterial α-amylase (BαA), Taka-amylase A (TAA) and keyhole-limpet haemocyanin (KLH), and the 2,4-dinitrophenyl (DNP) and benzylpenicilloyl (BPO) groups as haptenic determinants. Lymphoid cells obtained from mice primed with a hapten-carrier conjugate could be effectively stimulated with a hapten-heterologous carrier conjugate, provided that lymphoid cells primed to the heterologous carrier were also present. In the carrier-primed lymphoid cell population, helper activity of thymus-derived cells developed earlier following carrier immunization than did the capacity of antibody-forming cell precursors (AFCP) to produce an effective anti-carrier antibody response upon secondary stimulation. Attempts to generate hapten-specific helper cell activity were unsuccessful. Thus, cells primed to one haptenic determinant failed to exert a helper function with cells primed to a second hapten upon subsequent administration to the two haptens together on the same heterologous carrier molecule. In order to distinguish among carrier determinant specificities which react with thymus-derived helper cells from those which react with bone marrow-derived AFCP, the capacity of various anti-carrier antibodies or antibody fragments to suppress either anti-carrier antibody production alone or together with helper cell function in adoptive secondary anti-hapten antibody responses was tested. In this system, it was found that 7S anti-carrier antibody suppressed the reaction of helper cells and carrier-specific AFCP such that both the anti-hapten and anti-carrier antibody responses were abrogated. By contrast, passively administered 3.5S fragments of anti-carrier antibodies selectively prevented the stimulation of carrier-specific AFCP to produce anti-carrier antibodies, but had no effect on the capacity of carrier-specific helper cells to facilitate the secondary anti-hapten antibody response. As expected, passively administered 7S anti-hapten antibodies selectively abrogated the production of anti-hapten, but not anti-carrier antibodies. These data are discussed in the context of suggesting that distinct determinant sites on carrier molecules are recognized independently by thymus-derived helper cells and by bone marrow-derived AFCP.
Nucleophilic Activation of Elemental Sulfur for Inverse Vulcanization and Dynamic Covalent Polymerizations (2018)

The accelerator effect of amine activators N-methylimidazole and 4-vinylaniline (4-VA) on inverse vulcanization and dynamic covalent polymerization (DCP) has been investigated. The sulfur polymer with self-activation comonomer 4-VA could also be used for low temperature DCP to incorporate some volatile monomers. Those approaches provide a new synthetic and rate accelerated processes to activate S8 for copolymerization processes with functional comonomers at lower temperatures and under a broader range of reaction conditions. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Clinical and virologic outcomes in high‐risk adult Epstein‐Barr virus mismatched organ transplant recipients (2017)

Epstein-Barr virus (EBV) D+/R- organ transplant recipients are a high-risk group for developing post-transplant lymphoproliferative disease (PTLD). Little data are available for prevention in the adult EBV mismatched population. We conducted a retrospective study of EBV D+/R- organ transplants performed during 2002-2014. Of the 153 patients identified, 82.4% patients received antiviral prophylaxis with valganciclovir for a median of 4.5 months (range: 0.8-22 months) and 36.6% underwent viral load monitoring in the first post-transplant year. EBV viremia developed in 67.2% monitored patients. In viremic patients, immunosuppression was reduced in 20/37(54.1%) in response to viremia and 17/37 (45.9%) received therapeutic dose valganciclovir. In patients with EBV viremia who received valganciclovir and/or had a reduction in immunosuppression and had sufficient viral load time points (n=31), 28 (90.3%) had a significant decline in viral load at day 14 (median log decline 0.49 (0.24-0.64), P<.001) and at day 30 (0.87 (0.52-1.21), P<.001). PTLD developed in 27 (15%) patients (biopsy proven=25, possible=2) at median 8 months (range: 2.4-130) post-transplant with the majority (81.5%) within the first year. In multivariate analysis, viral load monitoring and use of mycophenolate were associated with a lower incidence of PTLD. Antiviral prophylaxis was not associated with a lower risk of PTLD, but viral load monitoring and use of mycophenolate mofetil were protective.
On the bromine oxidation of hypophosphate: a 31P(18O) positional isotope investigation (1986)

B. V. L. Potter, J. Chem. Soc., Chem. Commun., 1986, 21 DOI: 10.1039/C39860000021
Polyaramides containing arylene sulfone ether linkages (1989)

Abstract Polyamides containing arylene sulfone ether linkages were synthesized from 4,4′[sulfonybis ( p ‐phenyleneoxy)] dibenzoyl chloride (SPCI), 3,3′‐[sulfonylbis ( p ‐phenyleneoxy)] dibenzoyl chloride (SMCl) and various aromatic diamines (ARD), by solution and interfacial polymerization techniques. In solution polymerization, the effect of various acid acceptors such as propylene oxide (PO), lithium hydroxide (LiOH) in the presence of lithium chloride (LiCl), and triethylamine (TEA) on teh molecular weight of the olyamides was studied. The effect of structure of studied. The effect of structur of various aromatic diamine sof molecular weight and thermal properties of polyamides was also studied. The polyamides prepared were characterized by solution viscosity, elemental analysis thermo‐gravimetric analysis, differential scanning calorimetry, and x‐ray diffraction. Physical and thermal properties of polyamides prepared from SPcl and Ard were compared with the polyamides prepared from SMCl and ARD.
Provision of a swing lock denture for a patient with Gorlin Goltz syndrome. (2012)

Swinglock dentures are used relatively infrequently but in cases of compromised anatomy or where the pattern of tooth loss is unfavourable, they provide a useful removable partial denture design option. The aim of this article is to provide a clear summary of the clinical and technical considerations necessary when providing a Swinglock denture.
Ellipsometric study of silicon nitride on gallium arsenide (1982)

A method for optimizing the sensitivity of ellipsometric measurements for thin dielectric films on semiconductors is described in simple physical terms. The technique is demonstrated for the case of sputtered silicon nitride films on gallium arsenide.
The interpretation of the spectral structure of Rayleigh scattered light from combustion gases (1976)

The determination of the temperature of combustion gases from Rayleigh scattered laser light can be greatly simplified if the effect of Brillouin scattering is assumed to be negligible. To define precisely the regimes in which this assumption is applicable, measurements of the broadening effect of Brillouin scattering on the R ayleigh spectra from nitrogen, oxygen, air and argon have been made with a Fabry-Perot spectrometer. These spectra were analyzed using a trimodal Gaussian model convoluted with the instrument function for the spectrometer. The results of this investigation indicate that if the value of a parameter y, the ratio of the wavelength of the fluctuations producing the scattering divided by 2..pi.. to the collision mean free path, is less than 0.1, Brillouin scattering is negligible. This criterion is shown to be satisfied in the post flame zone of an atmospheric pressure premixed hydrogen air flame.
vSlicer (2012)

Recent advances in virtualization technologies have made it feasible to host multiple virtual machines (VMs) in the same physical host and even the same CPU core, with fair share of the physical resources among the VMs. However, as more VMs share the same core/CPU, the CPU access latency experienced by each VM increases substantially, which translates into longer I/O processing latency perceived by I/O-bound applications. To mitigate such impact while retaining the benefit of CPU sharing, we introduce a new class of VMs called latency-sensitive VMs (LSVMs), which achieve better performance for I/O-bound applications while maintaining the same resource share (and thus cost) as other CPU-sharing VMs. LSVMs are enabled by vSlicer, a hypervisor-level technique that schedules each LSVM more frequently but with a smaller micro time slice. vSlicer enables more timely processing of I/O events by LSVMs, without violating the CPU share fairness among all sharing VMs. Our evaluation of a vSlicer prototype in Xen shows that vSlicer substantially reduces network packet round-trip times and jitter and improves application-level performance. For example, vSlicer doubles both the connection rate and request processing throughput of an Apache web server; reduces a VoIP server's upstream jitter by 62%; and shortens the execution times of Intel MPI benchmark programs by half or more.
SVBRDF-Invariant Shape and Reflectance Estimation from a Light-Field Camera (2017)

Light-field cameras have recently emerged as a powerful tool for one-shot passive 3D shape capture. However, obtaining the shape of glossy objects like metals or plastics remains challenging, since standard Lambertian cues like photo-consistency cannot be easily applied. In this paper, we derive a spatially-varying (SV)BRDF-invariant theory for recovering 3D shape and reflectance from light-field cameras. Our key theoretical insight is a novel analysis of diffuse plus single-lobe SVBRDFs under a light-field setup. We show that, although direct shape recovery is not possible, an equation relating depths and normals can still be derived. Using this equation, we then propose using a polynomial (quadratic) shape prior to resolve the shape ambiguity. Once shape is estimated, we also recover the reflectance. We present extensive synthetic data on the entire MERL BRDF dataset, as well as a number of real examples to validate the theory, where we simultaneously recover shape and BRDFs from a single image taken with a Lytro Illum camera.
ChemInform Abstract: 2,2′‐Bipyridyl‐6‐carbothioamide Derivatives as Potential Antitumor Agents. (1986)

4- and/or 4'-substituted 2,2'-bipyridyl-6-carbothioamides have been synthesized and tested for their activity against P-388 lymphocytic leukemia in mice. Of these, only 4'-nitro-2,2'-bipyridyl-6-carbotioamide (IV c) proved to be active.
p-Cresol As a Reversible Acylium Ion Scavenger in Solid-Phase Peptide Synthesis (1998)

In this work we have defined the nature of the p-cresol and p-thiocresol adducts generated from acylium ions during HF cleavage, following contemporary Boc/benzyl solid-phase peptide synthesis. Contrary to the results in previous reports, we found that both p-cresol and p-thiocresol predominantly form aryl esters under typical cleavage conditions. Initially we investigated a number of small peptides containing either a single glutamate residue or a C-terminal long-chain amino acid which allowed us to unambiguously characterize the “scavenged” side products. Whereas, the p-cresol esters are stable at 0 °C they rearrange irreversibly at higher temperatures (5−20 °C) to form aryl ketones. By contrast, p-thiocresol esters do not undergo a Fries rearrangement but readily undergo further additions of p-thiocresol to form ketenebisthioacetals and trithio ortho esters, even at low temperatures. Importantly, we found by LC/MS and FT-ICR MS analysis that peptides containing p-cresol esters at glutamyl side chains are susceptible to amidation and fragmentation reactions at these sites during standard mild base workup procedures. The significance of these side reactions was further demonstrated in the synthesis of neutrophil immobilization factor, a 26-residue peptide, containing four glutamic acid residues. The side reactions were largely avoided by mild hydrogen peroxide-catalyzed hydrolysis which converted the p-cresol adducts to the free carboxylic acids in near quantitative yield. The choice of p-cresol as a reversible acylium ion scavenger when coupled with the simple workup conditions described is broadly applicable to Boc/benzyl peptide synthesis and will significantly enhance the quality of peptides produced.
Residual Viral Replication during Antiretroviral Therapy Boosts Human Immunodeficiency Virus Type 1-Specific CD8+T-Cell Responses in Subjects Treated Early after Infection (2002)

Human immunodeficiency virus type 1 (HIV-1)-infected subjects treated early after infection have preserved HIV-1-specific CD4+ T-cell function. We studied the effect of highly active antiretroviral therapy (HAART) on the frequency of HIV-1-specific CD8+ T cells in patients treated during early (n = 31) or chronic (n = 23) infection. The degree of viral suppression and time of initiation of treatment influenced the magnitude of the CD8+ T-cell response. HIV-1-specific CD8+ T cells can increase in number after HAART in subjects treated early after infection who have episodes of transient viremia.
The 1983 Nobel Prize in Chemistry (1983)

Henry Taube has been selected to&#13;\nreceive the 1983 Nobel Prize in Chemistry&#13;\nfor his pioneering work on the mechanisms&#13;\nof inorganic oxidation-reduction&#13;\n(redox) reactions. Taube was born in&#13;\nNeudorf, Saskatchewan, on 30 November&#13;\n1915, and he received B.S. (1935)&#13;\nand M.S. (1937) degrees at the University&#13;\nin Saskatoon. He moved to Berkeley&#13;\nto do his doctoral research (Ph.D., 1940)&#13;\nwith W. C. Bray, and he became a U.S.&#13;\ncitizen in 1941. He has held academic&#13;\nappointments at Cornell (1941 to 1946),&#13;\nChicago (1946 to 1961), and Stanford&#13;\n(since 1962) and is now the Marguerite&#13;\nBlake Wilbur Professor of Chemistry at&#13;\nStanford.
Studies of internal wave and bottom effects on broadband shallow-water propagation (1999)

Broadband numerical modeling of acoustic propagation through the continental-shelf environment is used to evaluate the impacts of various natural features on 50–1000 Hz signals. Previous studies have shown that thermocline depth variations due to internal waves, bores, or fronts cause mode coupling. Furthermore, if the coupling causes net flux of acoustic energy into efficiently propagating low-order modes, then more energy propagates to distant ranges, and vice versa. In addition, for moving internal waves the signal changes over time, with time scales of minutes. These effects are dependent on geoacoustic properties of the seafloor and on frequency. Details of the effects are quantified for various depths, bottom types, and frequencies. [Work supported by ONR Ocean Acoustics.]