gebhart/patrepeval huggingface dataset:
Measuring Code-Phase Differences due to Inter-Satellite Hardware Differences (2012)

This paper focuses on the hardware demonstration of pseudorange domain errors from nominal signal deformation, as seen at the output of actual hardware receivers. To see these errors in the current singlefrequency configuration, the following procedural steps were necessary to highlight the error contributions: • Careful siting of antenna to reduce multipath — as it is the other correlator spacing-dependent error source • Multiple “receivers” with wide front-end bandwidths and with the flexibility of implementing both narrow and wide correlator discriminators for tracking • A known, zero-baseline differential receiver configuration with common clock to remove all other common mode errors With these steps, the effects of nominal signal deformation on pseudorange domain performance are clearly and directly seen for the first time, verifying past results. The proposed method avoids specialized hardware such as large dish antennas; instead, widely-available COTS hardware and a more easily-accessible dish antenna are used. This provides a practical and convenient means of monitoring signal deformations and for testing and verifying various mitigation strategies. Furthermore, this method is easily adapted to upcoming multi-constellation, multi-frequency systems.
A Robust Mean-field Game of Boltzmann-Vlasov-like Traffic Flow (2022)

Historically, traffic modeling approaches have taken either a particle-like (microscopic) approach, or a gaslike (meso- or macroscopic) approach. Until recently with the introduction of mean-field games to the controls community, there has not been a rigorous framework to facilitate passage between controls for the microscopic models and the macroscopic models. We begin this work with a particle-based model of autonomous vehicles subject to drag, unknown disturbances, noise, and a speed limit in addition to the control.We formulate a robust stochastic differential game on the particles. We pass formally to the infinite-particle limit to obtain a robust mean-field game PDE system. We solve the mean-field game PDE system numerically and discuss the results. In particular, we obtain an optimal control which increases the bulk velocity of the traffic flow while reducing congestion.
Defects in coding joint formation in vivo in developing ATM-deficient B and T lymphocytes (2007)

Ataxia-telangiectasia mutated (ATM)-deficient lymphocytes exhibit defects in coding joint formation during V(D)J recombination in vitro. Similar defects in vivo should affect both T and B cell development, yet the lymphoid phenotypes of ATM deficiency are more pronounced in the T cell compartment. In this regard, ATM-deficient mice exhibit a preferential T lymphopenia and have an increased incidence of nontransformed and transformed T cells with T cell receptor alpha/delta locus translocations. We demonstrate that there is an increase in the accumulation of unrepaired coding ends during different steps of antigen receptor gene assembly at both the immunoglobulin and T cell receptor loci in developing ATM-deficient B and T lymphocytes. Furthermore, we show that the frequency of ATM-deficient alphabeta T cells with translocations involving the T cell receptor alpha/delta locus is directly related to the number of T cell receptor alpha rearrangements that these cells can make during development. Collectively, these findings demonstrate that ATM deficiency leads to broad defects in coding joint formation in developing B and T lymphocytes in vivo, and they provide a potential molecular explanation as to why the developmental impact of these defects could be more pronounced in the T cell compartment.
Effects of Long-term Rofecoxib on Gastric Intestinal Metaplasia: Results of a Randomized Controlled Trial (2006)

There was no trend to suggest that treatment with rofecoxib for 2 years resulted in the regression of gastric IM. Although our findings cast doubt on the reversibility of gastric IM by COX-2 inhibitor, further studies are needed to establish the role of COX-2 inhibitors in different stages of gastric carcinogenesis.
Review: Perspectives on Web Services—Applying SOAP, WSDL and UDDIto Real-World Projects (2004)

ISSN:0010-4620
Multiscale edge grammars for complex wavelet transforms (2002)

Wavelet domain algorithms have risen to the forefront of image processing. The power of these algorithms is derived from the fact that the wavelet transform restructures images in a way that makes statistical modeling simpler. Since edge singularities account for the most important information in images, understanding how edges behave in the wavelet domain is the key to modeling. In the past, wavelet-domain statistical models have codified the tendency for wavelet coefficients representing an edge to be large across scale. We use the complex wavelet transform to uncover the phase behavior of wavelet coefficients representing an edge. This allows us to design a hidden Markov tree model that can discriminate between large magnitude wavelet coefficients caused by texture regions and ones caused by edges.
Bilateral peripheral neural activity observed in vivo following unilateral nerve injury. (2013)

Manganese-enhanced magnetic resonance imaging (MRI) is a surrogate method to measure calcium content in nervous system since manganese physiologically follows calcium. Manganese is detectable in MRI and therefore visualizes structures and cell populations that actively regulate calcium. Since calcium is actively recruited for the transmission of action potentials, our purpose is to validate manganese-enhanced MRI for detection of changes in lumbar nerves related to nociception. A neuropathic pain model was created by chronic constrictive injury of the left sciatic nerve of Sprague-Dawley rats. Behavioral measurements, using von Frey’s tests, confirmed the presence of significant allodynia in the left hind limb of animals in the injured group. T1-weighted fast spin echo images were obtained of the lumbar cord and plexus of animals with injured left sciatic nerve and uninjured animals (control) scanned in a 7 Tesla magnet after intraperitoneal manganese chloride administration four weeks after surgery. Lumbar nerve roots and sciatic nerves in the injured group show increased normalized manganese-enhanced MRI signal, representing manganese enhancement, compared to the control group. In conclusion, animals with neuropathic pain in the left hind limb show increased manganese uptake in not only the injured sciatic nerve but also in the contralateral uninjured sciatic nerve on manganese-enhanced MRI in vivo. Although poorly understood, this finding corroborates ex vivo finding of bilateral nociceptive-related molecular changes in the nervous system of unilateral pain models.
Specific plate assay for bacterial heparinase (1990)

A procedure was developed for detecting heparinase activity on heparin agar plates. The method is based on the differential precipitation of heparin and heparinase-generated heparin fragments by protamine sulfate. Heparinase activity is detected by the presence of clear zones against a white background. This method can be used to screen for the expression of recombinant heparinase and to identify Flavobacterium heparinum mutants expressing heparinase constitutively.
Heparin release from thermosensitive polymer coatings: in vivo studies (1995)

Biomer/poly(N-isopropylacrylamide)/[poly(NiPAAm)] thermosensitive polymer blends were prepared and their application as heparin-releasing polymer coatings for the prevention of surface-induced thrombosis was examined. The advantage of using poly (NiPAAm)-based coatings as heparin-releasing polymers is based on the unique temperature-dependent swelling of these materials. At room temperature, i.e., below the lower critical solution temperature (LCST) of poly (NiPAAm), the Biomer/(poly(NiPAAm) coatings are highly swollen. The high swelling enables fast loading of hydrophilic macromolecules (e.g., heparin) into the coating by a solution sorption technique. At a body temperature, i.e., above the LCST of poly (NiPAAm) the coatings are in a deswollen state and the absorbed macromolecules may be slowly released from a dense coating via a diffusion controlled mechanism. Biomer/poly(NiPAAm) coatings were obtained by blending and coprecipitation of the two linear polymers, Biomer and (poly(NiPAAm). The structure and water-swelling properties of the coatings were examined. Significant differences in water swelling at room temperature (RT) and 37 degrees C were observed as a result of the thermosensitivity of poly (NiPAAm). The surface structure of the coatings in dry and swollen states at RT and 37 degrees C was examined by scanning electron microscopy. Heparin was loaded into the coatings via a solution sorption at room temperature. Kinetic studies of heparin loading demonstrated that maximum loading was obtained within 1 h. The in vitro (37 degrees C) release profiles were characterized by a rapid initial release due to the squeezing effect of the collapsing polymer network, followed by a slower release phase controlled by heparin diffusion through the dense coating. The short-term antithrombogenicity of intravenous polyurethane catheters coated with heparin-releasing Biomer/poly(NiPAAm) thermosensitive coating was evaluated in a canine animal model. The results show that the heparin release from Biomer/poly(NiPAAm)-coated surfaces resulted in a significant reduction of thrombus formation on test surfaces in contact with venous blood as compared to control surfaces.
FPGA-based high performance page layout segmentation (2002)

A page layout segmentation algorithm for locating text, background and halftone areas is presented. The algorithm has been implemented on Splash 2-an FPGA-based array processor. The speed as determined by the Xilinx synthesis tools projects an application speed of 5 MHz. For documents of size 1,024/spl times/1,024 pixels, a significant speedup of two orders of magnitude compared to a SparcStation 20 has been achieved.
Demonstration of an 4.2 K analog switch matrix in a standard 0.7 μ CMOS process (2002)

In this extended abstract a 4x4 Field Programmable Analogue Array or switch matrix is presented. Design and preliminary data will be discussed.
High‐resolution NMR spectroscopic trends and assignment rules of metal‐free, metallated and substituted corroles (2004)

Major advances over the last few years have facilitated the synthesis of a large variety of meso-only substituted corroles that display interesting catalytic, therapeutic and photophysical properties. This work is the first to study extensively the NMR spectral characteristics of both metallated and non-metallated triarylcorroles in various organic solvents and provide guidelines for easy and reliable assignments of 1D 1H spectra from trends of J coupling constants and chemical shifts. An excellent correlation is found between C=C bond lengths derived from 3J(H,H) values and experimental lengths determined by x-ray crystallography of the same molecules. The nuclear Overhauser effect provides a robust 1D 1H NMR tool for determining the selectivity of electrophilic substitutions. Variable-temperature NMR and isotopic labelling reveal a single preferred tautomerization state and unsymmetric ring orientations at -70 degrees C. The beta-pyrrole protons demonstrate long-range heteronuclear couplings with the coordination core (15N) and with the ortho-19F nuclei of the meso-carbon aryl rings. In sum, application of multinuclear magnetic resonance to corroles and their metal complexes, through the compilation of chemical shifts and J couplings and the recognition of trends therein, provides basic information essential to reliable spectral assignments. Additionally, the conclusions drawn about the structures of corroles and the electron densities at various positions of the corrole macrocycle resulting from the application of high-resolution NMR techniques are of importance to an in-depth understanding of the molecular interactions and processes of this relatively new and rapidly expanding class of compounds.
Indoor and outdoor experimental trials in 28-GHz band for 5G wireless communication systems (2015)

This paper presents the overview of the experimental trial for the 5th generation (5G) mobile communication systems based on the collaboration between Samsung Electronics and NTT DOCOMO. In order to tackle rapidly increasing traffic for 2020 and beyond, new radio access network for the 5G mobile communication systems will introduce the use of higher-frequency bands such as spectra higher than 10 GHz to achieve higher capacity and super high bit rate transmission of several tens of Gbps. The target of this experimental trial is to evaluate the effectiveness of using 28-GHz band with super-wide bandwidth of 800 MHz for 5G mobile communication systems. Firstly, the technical concept of this trial and the prototype design of the experimental system are presented. Massive multiple-input multiple-output (MIMO) technique is attracting attention to compensate for large path-loss in higher frequency bands. In this experimental trial, the beamforming (BF) based on Massive MIMO is introduced to the transmission using 28-GHz band. Some results of the indoor and outdoor experiments are also shown to evaluate the feasibility of using 28-GHz band with 800-MHz bandwidth.
Characterization of the Tissue-Bioceramic Interface In Vivo Using New Preparation and Analytical Tools (2006)

A key feature in the understanding of the mechanisms of integration of implant materials is a deepened in-sight of the elemental and molecular composition of the interface zone between the implant and tissue. To analyze the interface at the ultrastructural level, transmission electron microscopy (TEM) is needed. However, techniques to fabricate thin foils for TEM are difficult and time consuming. By using focused ion beam microscopy (FIB) for site-specific preparation of TEM-samples, intact interfaces between bioceramics and calcified tissue can be prepared. The site-specific accuracy of the technique is about 1 mm. By using a dual-beam FIB, which is a combined scanning electron and focused ion beam microscope, the sample can be imaged with both electrons and ions (generating both secondary electrons and ions). Results from interface studies between Ca-aluminate based orthopaedic cement, dental materials, HA-coated Ti-implants and bone are presented. The interfaces were imaged in scanning-TEM and bright field mode, the crystal structures were determined using electron diffraction and elemental composition analyzed with energy dispersive spectroscopy. The technique fulfils a demand to correlate the surface properties of bioceramic implants with the structure and composition of preserved interfaces with tissues.
Integrated automatic expression prediction and speech synthesis from text (2013)

Getting a text to speech synthesis (TTS) system to speak lively animated stories like a human is very difficult. To generate expressive speech, the system can be divided into 2 parts: predicting expressive information from text; and synthesizing the speech with a particular expression. Traditionally these blocks have been studied separately. This paper proposes an integrated approach, sharing the expressive synthesis space and training data across the two expressive components. There are several advantages to this approach, including a simplified expression labelling process, support of a continuous expressive synthesis space, and joint training of the expression predictor and speech synthesiser to maximise the likelihood of the TTS system given the training data. Synthesis experiments indicated that the proposed approach generated far more expressive speech than both a neutral TTS and one where the expression was randomly selected. The experimental results also showed the advantage of a continuous expressive synthesis space over a discrete space.
Investigating disk evolution: A high spatial resolution mid-infrared survey of T Tauri stars (2005)

We present a high spatial resolution, 10-20 micron survey of 65 T Tauri binary stars in Taurus, Ophiuchus, and Corona Australis using the Keck 10 m telescopes. Designed to probe the inner ~1 AU region of the circumstellar disks around the individual stellar components in these binary systems, this study increases the number of binaries with spatially resolved measurements at 10 micron by a factor of ~5. Combined with resolved near-infrared photometry and spectroscopic accretion diagnostics, we find that ~10% of stars with a mid-infrared excess do not appear to be accreting. In contrast to an actively accreting disk system, these passive disks have significantly lower near-infrared colors that are, in most cases, consistent with photospheric emission, suggesting the presence of an inner disk hole. In addition, there appears to be a spectral type/mass dependence associated with the presence of a passive disk, with all passive disks occurring around M type stars. The possibility that the passive disks are caused by the presence of an as yet undetected companion at a small separation (0.3-3 AU) is possible for any individual system, however, it cannot account for the spectral type dependence of the passive disk sample as a whole. We propose that these passive disks represent a subset of T Tauri stars that are undergoing significant disk evolution. The fraction of observed passive disks and the observed spectral type dependence can both be explained by models of disk evolution that include disk photoevaporation from the central star. (abridged).
Epigenetic age acceleration in frontotemporal lobar degeneration: a comprehensive analysis in the blood and brain (2023)

Abstract Frontotemporal lobar degeneration (FTLD) includes a heterogeneous group of disorders pathologically characterized by the degeneration of the frontal and temporal lobes. In addition to major genetic contributors of FTLD such as mutations in MAPT, GRN , and C9orf72 , recent work has identified several epigenetic modifications including significant differential DNA methylation in DLX1 , and OTUD4 loci. As aging remains to be one of the major risk factors for FTLD, we investigated the presence of accelerated epigenetic aging in FTLD compared to controls. We calculated epigenetic age in both peripheral blood and brain tissues of multiple FTLD subtypes using several DNA methylation clocks, i.e., DNAmClock Multi , DNAmClock Hannum , DNAmClock Cortical , GrimAge and PhenoAge, and determined age acceleration and its association with different cellular proportions and clinical traits. Significant epigenetic age acceleration was observed in the peripheral blood of both frontotemporal dementia (FTD) and progressive supranuclear palsy (PSP) patients compared to controls with DNAmClock Hannum , even after accounting for confounding factors. A similar trend was observed with both DNAmClock Multi and DNAmClock Cortical in post-mortem frontal cortex tissue of PSP patients and in FTLD cases harboring GRN mutations. Our findings support that increased epigenetic age acceleration in the peripheral blood could be an indicator for PSP and to a smaller extent, FTD.
Supplementary Figure Legend from An <i>In Vivo</i> Immunotherapy Screen of Costimulatory Molecules Identifies Fc-OX40L as a Potent Reagent for the Treatment of Established Murine Gliomas (2023)

&lt;p&gt;PDF file, 72K.&lt;/p&gt;
Emulsion Resolution in Electrostatic Processes (1999)

Many oil production processes present a significant challenge to the primary separation and dehydration equipment designer and operator. Such processes include innovative production techniques, long pipelines, high-pressure transfer pumps, high shear mixers, gas-lift techniques, submersible production pumps, intermediate oil storage, batch processing methods, flow line pigging, and well treatment chemicals. Any combination of these production and processing techniques can produce an oil history that the equipment designer cannot and should not ignore. Furthermore, the nature of petroleum emulsions changes continuously as the producing field depletes and production methods change. Timely laboratory analysis can be used by the operator to effectively define the stability of the petroleum emulsion and determine the most significant destabilizing variables such as chemicals, viscosity, and shear energy. Numerous techniques are available to the equipment designers and operators to destabilize and resolve petroleum emulsions. These techniques include the traditional application of demulsifiers, temperature, and retention time as well as electrostatics including nontraditional methods of modulated or pulsed voltage control. Optimizing these numerous variables and techniques presents a significant and perpetual challenge for the designer and operator. This paper describes the characteristics of water-in-oil emulsions typically handled and resolved by electrostatic processes, including dehydrating and desalting. This overview describes the upstream production parameters affecting the nature and characteristics of crude oil emulsions and the processing variables influencing the effectiveness of traditional and nontraditional electrostatic processes. Several unique examples are presented to support the conclusions of this paper.
Strain compensated In/sub 1-x/Ga/sub x/As (x&gt;0.47) quantum well photodiodes for extended wavelength operation (2002)

The use of highly strained (-1.8%) InGaAs quantum wells for the detection of optical radiation beyond the InP lattice-matched bandgap of 1.65 /spl mu/m wavelength is reported. Excellent crystal quality for up to 50 quantum wells is maintained through strain compensation using tensile InGaP. Transmission electron microscopy and double crystal X-ray diffraction reveal smooth interfaces and no observable defects for In/sub 0.83/Ga/sub 0.17/As layers with widths less than 80 /spl Aring/. Single-pass quantum efficiencies of 33% have been achieved at 1.95 /spl mu/m wavelength using a 50 period, strain compensated p-i-n multiple-quantum well structure in a top illuminated mesa device.
ChemInform Abstract: Thermal Intramolecular Isomerization of 2‐Isoselenocyanato‐5,5‐ dimethyl‐1,3,2‐dioxaphosphorinane into 2‐Cyano‐2‐selenoxo‐5,5‐dimethyl‐ 1,3,2‐dioxaphosphorinane. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Shear-Layer Instabilities Of A Pulsed Stack-Issued Transverse Jet (2013)

Shear-layer instabilities of a pulsed stack-issued transverse jet were studied experimentally in a wind tunnel. Jet pulsations were induced by means of acoustic excitation. Streak pictures of the smoke-flow patterns illuminated by the laser-light sheet in the median plane were recorded with a high-speed digital camera. Instantaneous velocities of the shear-layer instabilities in the flow were digitized by a hot-wire anemometer. By analyzing the streak pictures of the smoke-flow visualization, three characteristic flow modes, synchronized flapping jet, transition, and synchronized shear-layer vortices, are identified in the shear layer of the pulsed stack-issued transverse jet at various excitation Strouhal numbers. The shear-layer instabilities of the pulsed stack-issued transverse jet are synchronized by acoustic excitation except for transition mode. In transition flow mode, the shear-layer vortices would exhibit a frequency that would be twice as great as the acoustic excitation frequency.