MP37-07 WHO WILL BENEFIT MOST FROM PARTIAL NEPHRECTOMY IN T1B TUMORS?: PREDICTIVE FACTORS FOR FUNCTIONAL OUTCOME AFTER RADICAL NEPHRECTOMY (2019)

You have accessJournal of UrologyKidney Cancer: Localized: Surgical Therapy II (MP37)1 Apr 2019MP37-07 WHO WILL BENEFIT MOST FROM PARTIAL NEPHRECTOMY IN T1B TUMORS?: PREDICTIVE FACTORS FOR FUNCTIONAL OUTCOME AFTER RADICAL NEPHRECTOMY Joon Chae Na*, Jun Jinhyung, Hyun Ho Han, Hyung Ho Lee, Won Sik Jang, Young Eun Yoon, Kwang Hyun Kim, Won Sik Ham, Young Sig Kim, Joong Shik Lee, Koon Ho Rah, Young Deuk Choi, and Woong Kyu Han Joon Chae Na*Joon Chae Na* More articles by this author , Jun JinhyungJun Jinhyung More articles by this author , Hyun Ho HanHyun Ho Han More articles by this author , Hyung Ho LeeHyung Ho Lee More articles by this author , Won Sik JangWon Sik Jang More articles by this author , Young Eun YoonYoung Eun Yoon More articles by this author , Kwang Hyun KimKwang Hyun Kim More articles by this author , Won Sik HamWon Sik Ham More articles by this author , Young Sig KimYoung Sig Kim More articles by this author , Joong Shik LeeJoong Shik Lee More articles by this author , Koon Ho RahKoon Ho Rah More articles by this author , Young Deuk ChoiYoung Deuk Choi More articles by this author , and Woong Kyu HanWoong Kyu Han More articles by this author View All Author Informationhttps://doi.org/10.1097/01.JU.0000556037.26064.7eAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVES: Partial nephrectomy is progressively being utilized for larger tumors, however it is frequently challenging. In this study we aimed to explore which patients with T1b tumors will benefit most from partial nephrectomy by studying the predictive factors for functional outcome after radical nephrectomy. METHODS: Patients with localized T1b renal cancer who had been treated by radical nephrectomy from Nov. 2005 to Jan. 2016 were reviewed. Functional recovery of >90% from preoperative eGFR during 3-years post-nephrectomy was studied. Those with multiple tumors, ESRD, history of transplantation, and urologic malformation such as horseshoe kidney were excluded from the study. RESULTS: During the study period 211 patients were included in the study. 41 patients were included in the recovery group (>90% recovery) and 170 patients were included in the non-recovery group (≤90% recovery). Patients in the recovery group were more likely to be female (53.7% vs 30.0%, p=0.004), ASA class1 (58.5% vs 41.8%, p=0.048), and CKD grade3 (12.2% vs 3.5%). On multivariable logistic regression analysis and cox regression analysis these three factors remained as significant factors predicting >90% recovery of renal function. (Table 1A, Figure 1) The same factors were also significant predictors of percentile functional recovery on multivariable linear regression analysis. (Table 1B). CONCLUSIONS: Among patients presenting with T1b renal tumors those who are male, ASA class 2 or higher, and CKD grade2 or lower are less likely to recover renal function after radical nephrectomy. These patients are more likely to benefit from nephron sparing surgery. Source of Funding: none Seoul, Korea, Republic of; Goyang, Korea, Republic of; Seoul, Korea, Republic of; Goyang, Korea, Republic of; Seoul, Korea, Republic of© 2019 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 201Issue Supplement 4April 2019Page: e525-e526 Advertisement Copyright & Permissions© 2019 by American Urological Association Education and Research, Inc.MetricsAuthor Information Joon Chae Na* More articles by this author Jun Jinhyung More articles by this author Hyun Ho Han More articles by this author Hyung Ho Lee More articles by this author Won Sik Jang More articles by this author Young Eun Yoon More articles by this author Kwang Hyun Kim More articles by this author Won Sik Ham More articles by this author Young Sig Kim More articles by this author Joong Shik Lee More articles by this author Koon Ho Rah More articles by this author Young Deuk Choi More articles by this author Woong Kyu Han More articles by this author Expand All Advertisement PDF downloadLoading ...