gebhart/patrepeval huggingface dataset:
Schlußbetrachtung — Total Quality Management als Kosten/Nutzen-Managementphilosophie (1995)

Der grundlegende Baustein eines integrierten Kosten/Nutzen-Managements ist die „richtige“ Philosophie, also die Art des Denkens und des Handelns aller Betroffenen.561 Eine solche Philosphie ist das Total Quality Management (TQM). Eine Befragung von IuD-Leitern hat ergeben, daß beim ranking der IuD-Erfolgsfaktoren die Qualität von lnformationsdienstleistungen als wichtigster eingestuft wird. Danach erst folgen Faktoren, wie IuD-Kompetenz, Schnelligkeit der lnformationsversorgung oder Wirtschaftlichkeit der Leistungserbringung.562 Ausgangspunkt einer qualitätsorientierten Kosten/Nutzen-Managementphilosophie ist der Nutzer mit seinen Wünschen, Ennartungen und Anforderungen an die Dienstleistungen.
Sparse distributed associative memory for the identification of aerospace acoustic sources (1993)

A pattern recognition system has been developed to classify five different aerospace acoustic sources. The system consists of one microphone for data acquisition, a preprocessor, a feature selector, and a classifier. In this paper the performances of an associative memory classifier and a neural network classifier are compared with the performance of a previously designed system. Source noises are classified using features calculated from the time and frequency domain. Each classifier is trained to classify source noises correctly using a set of known sources. After training, the classifier is tested with unknown sources. Results show that over 96% of the sources were identified correctly with the new associative memory classifier. The neural network classifier identified over 81% of the sources correctly.
Soft Embossing of Nanoscale Optical and Plasmonic Structures in Glass (2011)

We describe here soft nanofabrication methods using spin-on glass (SOG) materials for the fabrication of both bulk materials and replica masters. The precision of soft nanofabrication using SOG is tested using features on size scales ranging from 0.6 nm to 1.0 μm. The performance of the embossed optics is tested quantitatively via replica patterning of new classes of plasmonic crystals formed by soft nanoimprinting of SOG. These crystals are found to offer significant improvements over previously reported plasmonic crystals fabricated using embossed polymeric substrate materials in several ways. The SOG structures are shown to be particularly robust, being stable in organic solvent environments and at high temperatures (∼450 °C), thus extending the capacities and scope of plasmonic crystal applications to sensing in these environments. They also provide a stable, and particularly high-performance, platform for surface-enhanced Raman scattering. We further illustrate that SOG embossed nanostructures can serve as regenerable masters for the fabrication of plasmonic crystals. Perhaps most significantly, we show how the design rules of plasmonic crystals replicated from a single master can be tuned during the embossing steps of the fabrication process to provide useful modifications of their optical responses. We illustrate how the strongest feature in the transmission spectrum of a plasmonic crystal formed using a single SOG master can be shifted precisely in a SOG replica between 700 and 900 nm for an exemplary design of a full 3D plasmonic crystal by careful manipulation of the process parameters used to fabricate the optical device.
SAP HANA Advanced Data Modeling (2015)

Want the latest and greatest info on advanced SAP HANA data modeling from the SAP HANA architects at SAP Labs in Palo Alto? Then this is the only book for you. Through step-by-step instructions and screenshots, this book will teach you how to design predictive, simulation, and optimization models. From information views to AFL models, you'll learn to scale for large datasets and performance tune your models to perfection. * Learn how to model complex logic in SAP HANA * Build predictive models with R, PAL, and more * Use performance tuning tools to get the most of out of your SAP HANA models Complex Logic Learn how to design SAP HANA data models to represent complex business logic, through practical examples and step-by-step modeling how-tos. Predictive Modeling Use PAL and R to build advanced predictive models that make the most of SAP HANA's predictive power. Performance Tuning Discover basic tuning techniques for your SAP HANA data models, such as avoiding long join paths, defining partitions, pushing down filters, and more. * Basic and advanced predictive modeling * SAP HANA modeling paradigms * Complex business logic * Analytic, attribute, and calculation views * Application Function Library models * PAL * SQL * R procedures * Simulations and optimization * Performance tuning * SAP HANA database
ChemInform Abstract: SUBSTITUENT EFFECTS ON THE CLAISEN REARRANGEMENT. THE ACCELERATING EFFECT OF A 6‐DONOR SUBSTITUENT (1984)

Abstract Die von der Claisen‐Umlagerung des Diethers (Ia) bekannte Differenzierung zwischen einem schnellen (beschleunigten) ersten und einem sehr langsamen zweiten Reaktionsschritt zeigt sich beim Cyclohexenanalogen (Ib) nicht.
Dark-state-based three-element vector model for the stimulated Raman interaction (1997)

In this paper we develop a three-element vector model to describe the stimulated Raman interaction in a \ensuremath{\Lambda} system. This model is valid over the range of interaction energies for which the excited state follows the ground states adiabatically. We use the model to present simple physical interpretations of the generation of Raman-Ramsey fringes in a separated field excitation, the ac Stark shift in the Raman clock, the ultrahigh-resolution mapping of microwave phase using Raman probes, and the coherent transfer of population by adiabatic passage for atomic beam splitters. The expressions for observables are derived by inspection and agree quantitatively with published experimental results.
Optimization, 3D-Numerical Validations and Preliminary Experimental Tests of a Wound Rotor Synchronous Machine (2021)

In this paper, a complete methodology to design a modular brushless wound rotor synchronous machine is proposed. From a schedule of conditions and a chosen structure (with 7 phases, 7 slots and 6 poles), a non-linear and non-convex optimization problem is defined and solved using NOMAD (a derivative free local optimization code): the external volume is minimized under some constraints, which are the average torque equal to 5 Nm, the torque ripple less than 5%, the efficiency greater than 94%, and the surface temperature less than 85 °C. The constraints have to be computed using 2D-finite element simulations in order to reduce the CPU-time consumption for each NOMAD iteration. Moreover, a relaxation of this optimization problem makes it possible to provide an efficient starting point for NOMAD. Thus, a good optimal design is obtained, and it is then validated by using 3D electromagnetic and thermic numerical methods. These numerical verifications show that, inside the end-winding, the leakage flux is high. This yields a lot of iron losses in this machine. Moreover, the surface and coil temperature differences between the 2D and 3D numerical approaches are discussed. Finally, the machine prototype is built following the optimal dimensions and a POKI-POKITM assembly technology. Preliminary experimental tests are carried out, and the results are devoted to the comparison of measured and predicted 3D numerical results.
Hyperparathyroidism and gastroenteropancreatic hormone levels. (1985)

The diagnosis of multiple endocrine neoplasia (MEN) in patients with presumed hyperparathyroidism has important ramifications for patient management especially since as many as 20% of patients with hyperparathyroidism may have associated MEN. Gut hormone levels were measured before and after surgery in 28 patients who underwent resection of a single parathyroid adenoma for biochemical or clinical evidence of hyperparathyroidism. The mean serum calcium level was 11.9 +/- 0.2 mg/dl before surgery and 9.3 +/- 0.3 mg/dl after surgery (p less than 0.001). Two or more hormone levels were elevated in 32% of patients before surgery and 21% after surgery. The same hormone abnormalities (pancreatic polypeptide [PP] and gastrin) occurred 56% of the time. Of elevated preoperative levels of PP, 91% were in the normal range after surgery. In patients with elevated preoperative PP levels, the postoperative level of PP decreased by an average of 64% of the preoperative level. In 27% of patients the level increased more than double the preoperative value. In two of four patients with high levels of PP after surgery the serum calcium level failed to fall. Of 18 patients whose PP levels fell, 17 had a fall in serum calcium levels. Of six patients whose PP levels rose, four had a significant fall in calcium levels. There was no correlation between the absolute levels or the decremental change of calcium and the change in PP. Several abnormalities in gut hormone secretion occur in patients with primary hyperparathyroidism and a parathyroid adenoma. An elevated serum level of PP does not signify MEN syndrome and must be reevaluated after resection of the parathyroid adenoma. Failure of adequate tumor resection is attended by persistent elevation of serum calcium and PP levels.
Cascaded AMZ triplets: a class of demultiplexers having a monitor and control scheme enabling dense WDM on Si nano-waveguide PICs with ultralow crosstalk and high spectral efficiency (2021)

We propose a class of wavelength-division multiplexing (WDM) demultiplexers having a novel monitor and control scheme enabling dense WDM on Si nano-waveguide (NW) photonic integrated circuits (PICs), which had been impossible due to the critically small fabrication tolerance of the extremely miniaturized waveguide structure. With a computer simulation, we show our proposed demultiplexers enable crosstalk in the range of -50 to -40 dB, flat-topped spectrum for high spectral efficiency, and channel counts as large as 64. We have experimentally evaluated the validity of this type of demultiplexers by using a 4-ch WDM demultiplexer, which has shown total crosstalk of < -49 dB as a result of fully automatic control of heaters. This technology is expected to drastically shrink the size of dense WDM transceivers, paving the way for future sustainable scalability in the capacity of optical transceiver systems.
Vital Sign Detection Using Short-range mm-Wave Pulsed Radar (2021)

Proximity sensors have been developing through the last decades. Adopting a radiation source and analyzing the reflected signal, obstacles and surroundings can be sensed and detected from a distance without contact. The mm-wave radar systems provide considerable potential in vital sign detection compared to the other proximity sensing choices based on audio and ultrasonic waves or optical signaling. In this study, a 60 GHz radar system was employed for contactless vital sign detection, such as respiration and heartbeat rate. The potential of the system in measuring through the materials was studied in various transmission situations. Three different methods were examined for preparing the phase information, and a clinically certified heartbeat rate measurement tool analyzed the accuracy of the results. The suggested algorithm can scan the region in the radar field of view and capture exceptional features like the heartbeat rate with a median accuracy of 96.22%.
Lipopolysaccharide Tolerance in Human Primary Monocytes and Polarized Macrophages (2023)

Innate immune memory allows macrophages to adequately respond to pathogens to which they have been pre-exposed. To what extent different pattern recognition receptors, cytokines and resolution signals influence innate immune memory needs further elucidation. The present study assessed whether lipopolysaccharide (LPS) tolerance in monocytes and macrophages is affected by these factors. Human CD14<sup>+</sup> cells were isolated from peripheral blood, stimulated by LPS and re-stimulated after 3 days of resting. Hereafter, immune-responsive gene 1 (IRG-1), heme oxygenase 1 (HO-1), tumor necrosis factor α (TNF-α) and interleukin 6 (IL-6) expression were assessed. Our study revealed the following findings: (1) While pre-stimulation with the Toll-like receptor 4 ligand LPS inhibits the induction of IRG-1, TNF-α and IL-6 expression, pre-stimulation with TLR 1/2 ligands only affects cytokine production but not IRG-1 expression upon subsequent TLR4 engagement. (2) Prior TNF-α stimulation does not affect LPS tolerance but rather increases LPS-mediated cytokine expression. (3) Dimethyl itaconate (DMI) inhibits the expression of IRG-1 in a dose-dependent manner but does not affect TNF-α or IL-6 expression. (4) Docosahexaenoic acid (DHA) partly inhibits IRG-1 expression in monocytes but not in M<sub>(IFNγ)</sub> and M<sub>(IL-4)</sub> polarized macrophages. LPS tolerance is not affected in these cells by DHA. The data presented in this study partly corroborate and extend previous findings on innate immune memory and warrant further studies on LPS tolerance to gain a better understanding of innate immune memory at the molecular level.
Electrochemically Triggered Energy Release from an Azothiophene‐Based Molecular Solar Thermal System (2022)

Molecular solar thermal (MOST) systems combine solar energy conversion, storage, and release in simple one-photon one-molecule processes. Here, we address the electrochemically triggered energy release from an azothiophene-based MOST system by photoelectrochemical infrared reflection absorption spectroscopy (PEC-IRRAS) and density functional theory (DFT). Specifically, the electrochemically triggered back-reaction from the energy rich (Z)-3-cyanophenylazothiophene to its energy lean (E)-isomer using highly oriented pyrolytic graphite (HOPG) as the working electrode was studied. Theory predicts that two reaction channels are accessible, an oxidative one (hole-catalyzed) and a reductive one (electron-catalyzed). Experimentally it was found that the photo-isomer decomposes during hole-catalyzed energy release. Electrochemically triggered back-conversion was possible, however, through the electron-catalyzed reaction channel. The reaction rate could be tuned by the electrode potential within two orders of magnitude. It was shown that the MOST system withstands 100 conversion cycles without detectable decomposition of the photoswitch. After 100 cycles, the photochemical conversion was still quantitative and the electrochemically triggered back-reaction reached 94 % of the original conversion level.
Multiple-Antenna Signaling Over Fading Channels With Estimated Channel State Information: Capacity Analysis (2007)

<para xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> Multiple-antenna concepts for wireless communication systems promise high spectral efficiencies and improved error rate performance by proper exploitation of the randomness in multipath propagation. In this paper, we investigate the impact of channel uncertainty caused by channel estimation errors on the capacity of Rayleigh and Ricean block-fading channels. We consider a training-based multiple-antenna system that reserves a portion of time to sound the channel. The training symbols are used to estimate the channel state information (CSI) at the receiver by means of an arbitrary linear estimation filter. No CSI is assumed at the transmitter. Our analysis is based on an equivalent system model for training-based multiple-antenna systems which specifies the channel by the estimated (and hence, known) channel coefficients and an uncorrelated, data-dependent, multiplicative noise. This model includes the special cases of perfect CSI and no CSI. We present new upper and lower bounds on the maximum instantaneous mutual information to compute ergodic and outage capacities, and extend previous results to arbitrary (and possibly mismatched) linear channel estimators and to correlated Ricean fading. Several numerical results for single- and multiple-antenna systems with estimated CSI are included as illustration. </para>
Vertical cavity lasers on p -doped substrates (1997)

Vertical cavity surface emitting laser (VCSEL) diodes fabricated with inverted polarity, i.e. p-type bottom mirror and n-type top mirror, are reported with lower resistance and diode voltage and comparable output characteristics relative to similar conventional, non-inverted structures.
Analysis of a catalytic pathway via a covalent adduct of D52E hen egg white mutant lysozyme by further mutation (1999)

We previously demonstrated by X-ray crystallography and electrospray mass spectrometry that D52E mutant hen lysozyme formed a covalent enzyme-substrate adduct on reaction with N-acetylglucosamine oligomer. This observation indicates that D52E lysozyme may acquire a catalytic pathway via a covalent adduct. To explain this pathway, the formation and hydrolysis reactions of the covalent adduct were investigated. Kinetic analysis indicated that the hydrolysis step was the rate-limiting step, 60-fold slower than the formation reaction. In the formation reaction, the pH dependence was bell-shaped, which was plausibly explained by the functions of the two catalytic pKas of Glu35 and Glu52. On the other hand, the pH dependence in the hydrolysis was sigmoidal with a transition at pH 4. 5, which was identical with the experimentally determined pKa of Glu35 in the covalent adduct, indicating that Glu35 functions as a general base to hydrolyze the adduct. To improve the turnover rate of D52E lysozyme, the mutation of N46D was designed and introduced to D52E lysozyme. This mutation reduced the activation energy in the hydrolysis reaction of the covalent adduct by 1.8 kcal/mol at pH 5.0 and 40 degrees C but did not affect the formation reaction. Our data may provide a useful approach to understanding the precise mechanism of the function of natural glycosidases, which catalyze via a covalent adduct.
Correction to “Steady-State Catalytic Wave-Shapes for 2-Electron Reversible Electrocatalysts and Enzymes” (2023)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "Steady-State Catalytic Wave-Shapes for 2-Electron Reversible Electrocatalysts and Enzymes"Vincent FourmondVincent FourmondMore by Vincent Fourmondhttps://orcid.org/0000-0001-9837-6214, Carole BaffertCarole BaffertMore by Carole Baffert, Kateryna SybirnaKateryna SybirnaMore by Kateryna Sybirna, Thomas LautierThomas LautierMore by Thomas Lautier, Abbas Abou HamdanAbbas Abou HamdanMore by Abbas Abou Hamdan, Sébastien DementinSébastien DementinMore by Sébastien Dementinhttps://orcid.org/0000-0001-6168-5371, Philippe SoucaillePhilippe SoucailleMore by Philippe Soucaille, Isabelle Meynial-SallesIsabelle Meynial-SallesMore by Isabelle Meynial-Salles, Hervé BottinHervé BottinMore by Hervé Bottin, and Christophe Léger*Christophe LégerMore by Christophe Légerhttps://orcid.org/0000-0002-8871-6059Cite this: J. Am. Chem. Soc. 2023, 145, 12, 7048Publication Date (Web):March 21, 2023Publication History Received16 February 2023Published online21 March 2023Published inissue 29 March 2023https://pubs.acs.org/doi/10.1021/jacs.3c01652https://doi.org/10.1021/jacs.3c01652correctionACS PublicationsCopyright © 2023 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views777Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (1 MB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
ChemInform Abstract: Reaction of Constrained Bicyclic Aminophosphanes with Cyclopentadienyltricarbonylmolybdenum(II) Derivatives. (1986)

Abstract Die Donatorfähigkeit der beiden aufgezeichneten bicyclischen Aminophosphine gegenüber den Cyclopentadienyltricarbonyl‐Mo‐Komplexen (II), (IV) und dem analogen Hydrid wird untersucht und mit der des acyclischen (EtO) 2 PNMe 2 verglichen.
ChemInform Abstract: PREPARATION OF TRANS‐1,2‐BIS(TRIBUTYLSTANNYL)ETHYLENE (1976)

Abstract Lithiumchloracetylid (I) und Tri‐n‐butylzinnchlorid (II) liefern die Zwischenstufe (III), die mit Tri‐n‐butylzinnhydrid (IV) in hoher Ausbeute das trans‐1,2‐Bis‐(tri‐n‐butylstannyl)‐äthylen (V) gibt.
Deletion of residues 485-599 from the human insulin receptor abolishes antireceptor antibody binding and influences tyrosine kinase activation. (1994)

We have studied insulin and antireceptor antibody binding to mutated human insulin receptors deleted of residues 485-599 in the alpha-subunit by site-directed mutagenesis. Both normal and mutated receptors were expressed in rat HTC hepatoma cells. Cells expressing either the normal receptor or the mutated receptor retained the ability to bind insulin. In contrast to the normal receptor, however, the mutated receptor failed to interact with antireceptor alpha-subunit antibodies. The inability of the mutated receptor to interact with various antireceptor antibodies was further documented by photoaffinity labeling studies. In intact HTC cells expressing mutated receptors, basal insulin receptor tyrosine autophosphorylation was 2-fold elevated when compared to cells expressing normal receptors. In these cells, however, the response of this function to insulin was blunted. When receptors were isolated from these cells and assayed for both autophosphorylation and phosphotransferase activities toward the synthetic substrate poly(Glu, Tyr), the response to insulin was also blunted. To study the ability of the mutated receptor to transmembrane signal, insulin stimulation of S6 kinase activity was measured. In cells with mutated receptors, in concert with the insulin receptor kinase data, basal S6 kinase activity was elevated, and the response to insulin was blunted. The data suggest, therefore, that residues 485-599 in the alpha-subunit of the insulin receptor are critical for antireceptor antibody binding, but not for insulin binding. Moreover, these data suggest that residues 485-599 contain a regulatory domain for insulin regulation of receptor beta-subunit functions.
Implementing IPsec (2002)

The IP security protocols are sufficiently mature to benefit from multiple independent implementations and worldwide deployment. Towards that goal, we implemented the protocols for the BSD/OS, Linux, OpenBSD and NetBSD. While some differences in the implementations exist due to the differences in the underlying operating system structures, the design philosophy is common. A radix tree, namely the one used by the BSD code for routing purposes, is used to implement the policy engine; a transform table switch is used to make addition of security transformations an easy process; a lightweight kernel-user communication mechanism is used to pass key material and other configuration information from user space to kernel space, and to report asynchronous events such as requests for new keys from the kernel space to a user-level keying daemon; and two distinct ways of intercepting outgoing packets and applying the IPsec transformations to them are employed. The techniques used in our implementations are explained, differences in approaches are analysed, and hints are given to potential future implementers of new transforms.