gebhart/patrepeval huggingface dataset:
[Postero-superior glenoid impingement. Another impingement of the shoulder]. (1993)

An impingement occurring between the deep side of the supraspinatus tendon and the postero-superior edge of the glenoid cavity was evidenced in a young sports thrower presenting with a partial tear of the deep side of the tendon. This impingement occurred when the arm was in abduction-retropulsion and in forced lateral rotation. It was visualized on arthroscopy. The semiology was mixed, including signs of anterior instability and cuff impairment. The possible causes of partial tears of the deep side of the supraspinatus are discussed: sub-acromial impingement of NEER, anterior instability with secondary impingement, postero-superior glenoid impingement.
Increasing solvent polarity and addition of salts promote β‐phase poly(vinylidene fluoride) formation (2012)

Abstract This article investigates the effects of solvent polarity and salt addition on β‐phase poly(vinylidene fluoride) (PVDF) formation. Films were solvent cast in aprotic solvents of varying polarities with or without salt addition. Characterization was done by Fourier transformed infra‐red spectroscopy, differential scanning calorimetry, and scanning electron microscopy. Decreasing fractions of β‐phase PVDF was observed with increasing drying temperature when less polar solvents were used. The most polar solvent (hexamethylphosphoramide) consistently produced films with at least 90.0% β‐phase PVDF within the crystalline regions. Melting temperatures increased in correlation to absolute proportions of β‐phase PVDF. Salt addition increased the formation of β‐phase PVDF by 30%, with salts of higher valencies and smaller ionic radii resulting in more significant increases. Taken collectively, using solvents of higher polarities and addition of salts with high cationic valencies and small ionic radii will maximize β‐phase formation in solvent cast PVDF films. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
Anatomy and white matter connections of the fusiform gyrus (2020)

The fusiform gyrus is understood to be involved in the processing of high-order visual information, particularly related to faces, bodies, and stimuli characterized by high spatial frequencies. A detailed understanding of the exact location and nature of associated white-tracts could significantly improve post-operative morbidity related to declining capacity. Through generalized q-sampling imaging (GQI) validated by gross dissection as a direct anatomical method of identifying white matter tracts, we have characterized these connections based on relationships to other well-known structures. We created the white matter tracts using GQI and confirmed the tracts using gross dissection. These dissections demonstrated connections to the occipital lobe from the fusiform gyrus along with longer association fibers that course through this gyrus. The fusiform gyrus is an important region implicated in such tasks as the visual processing of human faces and bodies, as well as the perception of stimuli with high spatial frequencies. Post-surgical outcomes related to this region may be better understood in the context of the fiber-bundle anatomy highlighted by this study.
Interaction of murine MHC class I molecules with tapasin and TAP enhances peptide loading and involves the heavy chain alpha3 domain. (1999)

In human cells the association of MHC class I molecules with TAP is thought to be mediated by a third protein termed tapasin. We now show that tapasin is present in murine TAP-class I complexes as well. Furthermore, we demonstrate that a mutant H-2Dd molecule that does not interact with TAP due to a Glu to Lys mutation at residue 222 of the H chain (Dd(E222K)) also fails to bind to tapasin. This finding supports the view that tapasin bridges the association between class I and TAP and implicates residue 222 as a site of contact with tapasin. The inability of Dd(E222K) to interact with tapasin and TAP results in impaired peptide loading within the endoplasmic reticulum. However, significant acquisition of peptides can still be detected as assessed by the decay kinetics of cell surface Dd(E222K) molecules and by the finding that prolonged viral infection accumulates sufficient target structures to stimulate T cells at 50% the level observed with wild-type Dd. Thus, although interaction with tapasin and TAP enhances peptide loading, it is not essential. Finally, a cohort of Dd(E222K) molecules decays more rapidly on the cell surface compared with wild-type Dd molecules but much more slowly than peptide-deficient molecules. This suggests that some of the peptides obtained in the absence of an interaction with tapasin and TAP are suboptimal, suggesting a peptide-editing function for tapasin/TAP in addition to their role in enhancing peptide loading.
Enhanced SWEET protocol for energy efficient wireless sensor networks (2013)

SWEET routing protocol is one of the many protocols developed for cluster formation and routing in wireless sensor networks. The SWEET protocol is a decentralized clustering protocol, it uses timers and interim updated cluster head estimation probability. This paper focus on the details of the initialization waiting time, sleeping mode and base station in order to increase the life cycle of the network. The initial waiting time's resizing procedure is carried by a weighting factor which is computed from the delay slot time and delay frame time. Other improvements are the introduction of sleeping mode energy saving technique. The last contribution is through the enabled base station's ability to become a cluster head. A simulation based performance evaluation of our proposed EN-SWEET protocol shows superiority in energy efficiency.
Lewis Acid–Doped Natural Phosphate: New Catalysts for the One‐Pot Synthesis of 3,4‐Dihydropyrimdin‐2(1 H )‐one (2005)

Abstract Inexpensive and readily available natural phosphate doped with metal halides is used to efficiently catalyze the three‐component condensation reaction of an aldehyde, a beta‐keto ester, and urea to afford the corresponding dihydropyrimidin‐2(1H)‐ones in high yields.
Crazy Sequential Representations: Base 3 up to 9 (2019)

Abstract not available.
Quantitative In Situ Mechanical Characterization of the Effects of Chemical Functionalization on Individual Carbon Nanofibers (2012)

Abstract Carbon nanofibers (CNFs) have been used for applications in composite material for decades because of their unique mechanical, thermal, and electrical properties. Consequently, an in‐depth understanding of mechanical properties of individual CNFs, particularly after chemical functionalization, would provide important insight into its effective integration into composite materials. Fluorination and amination of CNFs is achieved and systematic chemical characterizations of functionalized CNFs are performed. An in situ tensile testing method, which combines a simple microfabricated device with a quantitative nanoindenter inside a scanning electron microscope (SEM) chamber, is used to measure mechanical properties of individual pristine, fluorinated, and amino‐functionalized CNFs. The nominal CNFs strengths follow the Weibull distribution and the fluorinated CNFs are found to possess higher nominal strength but similar strain when compared with the pristine and amino‐functionalized CNFs. SEM fracture surfaces analysis shows that all nanofibers failed in a similar cup‐and‐cone fashion. Microscopy image sof fluorinated CNFs reveal an unexpected change in the hollow core before and after fiber fracture, which is attributed to the possible effects of fluorination‐induced compression on nanofiber surfaces. The results demonstrate the potential of fluorination for improving both the mechanical properties of CNFs and their successful integration into composites.
Resumé Writing (2008)

The purpose of a resumé is to obtain a job. Only a small fraction of resumés result in job interviews. The reader of resumés spends an average of 30 seconds on each one. To be successful, a resumé should be short, with the important information listed first. It should be well organized and neat. Often a resumé is tailored to a specific job, which would require rewriting the resumé for each new position.
Optimization for black-box objective functions using sensitivity information in SVM (2004)

In many practical engineering design problems, the form of objective function is not given explicitly in terms of design variables. Under this circumstance, it usually takes expensive computation time to obtain the value of objective function by some analysis such as structural analysis, fluid mechanic analysis, and so on. In order to make the number of analyses as few as possible, we suggest a method by which optimization is performed in parallel with predicting the form of objective function. In this paper, support vector machine (SVM) is employed in predicting the form of objective function, and genetic algorithms (GA) in searching the optimal value of the predicted objective function.
One of the Radioactive Consumer Products-Some Glaze Samples of Cloisonne Works. (1994)

Some glaze samples of cloisonne works, as one of the radioactive consumer products are studied. γ-Ray spectrum of the glaze measured by a high purity Ge detector shows peaks of γ-rays from234mPa, 234Paand234Thas well as235U.These glaze samples seem to be based on depleted uranium. The calculated radioactivity of uranium in 1g of glaze“extra gold”is 700 Bq. The results of dose equivalent measured by film badges prove that most of the dose is contributed by β-rays of uranium series elements and that the dose is independent of glaze thickness because of strong self-absorption of β-rays.
Analyse von Problemstrukturen in der Angehörigenbetreuung von Pflegenden (2008)

Aktuelle Veröffentlichungen in Pflegefachzeitschriften weisen vermehrt und in vielerlei Hinsicht darauf hin, von wie großer Bedeutung der nahe Kontakt zu Angehörigen für das Wohlbefinden und den Genesungsprozess schwerkranker Patienten ist. Gleichzeitig verringert eine gelungene Betreuung Angehöriger deren Belastungssymptomatik deutlich. In der Praxis findet die Angehörigenbetreuung jedoch im Spannungsfeld stetig wachsender Anforderungen und Arbeitsbelastungen für die Pflegenden statt. Um in dieser Situation die Angehörigenarbeit optimieren zu können, sollten deshalb auch die Schwierigkeiten berücksichtigt werden, welche sich für das Pflegepersonal im Rahmen der Betreuung Angehöriger ergeben. Die vorliegende Arbeit basiert auf einer Mitarbeiterbefragung des Pflegepersonals einer Intermediate-Care- und einer Intensivstation. Mittels Fragebogen wurden Problemstrukturen in der Angehörigenbetreuung von Pflegenden untersucht. Dabei wurden insgesamt 17 einzelne Aspekte aus folgenden Bereichen berücksichtigt: strukturelle Faktoren, Informationsweitergabe und spezielle Angehörigenprobleme. Die Analyse trifft sowohl quantitative Aussagen zur Häufigkeit des Auftretens verschiedener Problemaspekte als auch qualitative zu deren Belastungsintensität für die Pflegenden. Darüber hinaus wird das Resultat verschiedener Personengruppen miteinander verglichen, unter den Gesichtspunkten Stationszugehörigkeit, Beschäftigungsverhältnis, Ausbildungsstand und Alter der Pflegenden. Abschließend werden die Ergebnisse auf der Grundlage bestehender Erkenntnisse diskutiert und gewertet.
Phosphorylation of p70S6kcorrelates with increased skeletal muscle mass following resistance exercise (1999)

High-resistance exercise training results in an increase in muscle wet mass and protein content. To begin to address the acute changes following a single bout of high-resistance exercise, a new model has been developed. Training rats twice a week for 6 wk resulted in 13.9 and 14.4% hypertrophy in the extensor digitorum longus (EDL) and tibialis anterior (TA) muscles, respectively. Polysome profiles after high-resistance lengthening contractions suggest that the rate of initiation is increased. The activity of the 70-kDa S6 protein kinase (p70(S6k)), a regulator of translation initiation, is also increased following high-resistance lengthening contractions (TA, 363 +/- 29%; EDL, 353 +/- 39%). Furthermore, the increase in p70(S6k) activity 6 h after exercise correlates with the percent change in muscle mass after 6 wk of training (r = 0.998). The tight correlation between the activation of p70(S6k) and the long-term increase in muscle mass suggests that p70(S6k) phosphorylation may be a good marker for the phenotypic changes that characterize muscle hypertrophy and may play a role in load-induced skeletal muscle growth.
Morphological characterization of cellular and extracellular components of 7,12 dimethylbenz[a]anthracene induced melanoma tumours. (1987)

Subcutaneous tumours were induced in castrated golden Syrian hamsters by 7,12 dimethylbenz[a]anthracene (DMBA), an agent known to produce papillomas and carcinomas. The morphological characteristics of the cellular and extracellular constituents of the chemically-induced tumours were indicative of melanoma. Tumours were induced by three injections of DMBA into the jugular vein over a 3 month period. Dermal tumour development within the dorsal integument and groin region ultimately projected into the epidermis and occurred during the 3 month period subsequent to the last DMBA injection. Suspect melanoma tumours were excised and processed for light microscopic (LM) and transmission electron microscopic (TEM) studies. Histochemical staining methods facilitated the characterization of the differentiated tumour components in this hamster melanoma model. The model presented could allow observations from initial melanoma transformation events through advanced stages of metastasis within a window of 7 months.
Automatic Fingersign to Speech Translator (2010)

The aim of this project is to help the communication of two people, one hearing impaired and one visually impaired by converting speech to fingerspelling and fingerspelling to speech. Fingerspelling is a subset of sign language, and uses finger signs to spell letters of the spoken or written language. We aim to convert finger spelled words to speech and vice versa. Different spoken languages and sign languages such as English, Russian, Turkish and Czech are considered.
Surgical Techniques to Prevent Proximal Junctional Kyphosis (2019)

Dr. Fineberg is Orthopaedic Spine Fellow, and Dr. Phillips is Professor, Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. Harrison St, Ste 300, Chicago, IL 60612; E-mail: [email protected]. The authors, faculty, and all staff in a position to control the content of this CME activity, and their spouses/life partners (if any), have disclosed that they have no financial relationships with, or financial interests in, any commercial organizations relevant to this CME activity.Supplemental digital content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the newsletter's website (www.cssnewsletter.com).Lippincott Continuing Medical Education Institute is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. Lippincott Continuing Medical Education Institute designates this enduring material for a maximum of 1.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. To earn CME credit, you must read the CME article and complete the quiz and evaluation assessment survey on the enclosed form, answering at least 70% of the quiz questions correctly. This activity expires on March 31, 2021.
First results with SiPM tiles for TOF PET based on FBK RGB-HD technology (2015)

We present the first results of timing and energy resolution of two newly developed tiles based on FBK RGB-HD SiPMs. The first tile has dimensions of 32x32 mm2 and is composed of 8x8 SiPMs, with a regular pitch of 4 mm and a cell size of 25x25 μm2. Although manufactured with a standard bond wire technology, the tile achieves a fill factor at the tile level of 85%. We produced two versions: one with a single-ended and the other with differential readout. We tested the first prototypes with single-ended readout with a scintillator array, perfectly matching the tile pitch and composed of 8x8 LYSO crystals with dimensions of 4x4x22 mm3. First, we tested the tile using a single-channel setup, based on a fast, discrete amplifier, a digital oscilloscope and a PC, reading one SiPM at a time. At 20 °C, we measured an energy resolution of 10.7% FWHM. For the timing measurements we compared two conditions: when only one SiPM was biased and read, and when all the 64 SiPMs were biased but only one was read. At 20 °C, we measured a timing resolution of 200 ps FWHM in the first case, and 220 ps FWHM in the second case. Then, we tested the whole tile with a dedicated ASIC (PETA3), and measured the energy and timing resolution of two tiles in coincidence. The second tile is composed of 144 SiPMs, mounted on a water cooled, ceramic LTCC substrate. On the top side, it contains 12x12 SiPMs with a regular pitch of 2.5 mm. Also in this case, the SiPM technology is the RGB-HD with a cell size of 25x25 μm2. On the bottom side, four readout ASICs of the latest generation (PETA5) are flip-chip mounted. First results will be presented.
Synthesis of (±)-Emtricitabine and (±)-Lamivudine by Chlorotrimethylsilane-Sodium Iodide Promoted Vorbrüggen Glycosylation (2021)

By simply adding water and sodium iodide (NaI) to chlorotrimethylsilane (TMSCl), promotion of a Vorbrüggen glycosylation en route to essential HIV drugs emtricitabine (FTC) and lamivudine (3TC) is achieved. TMSCl-NaI in wet solvent (0.1 M water) activates a 1,3-oxathiolanyl acetate donor for N-glycosylation of silylated cytosine derivatives, leading to cis ox-athiolane products with up to 95% yield and >20:1 dr. This telescoped sequence is followed by recrystallization and borohydride reduction, resulting in rapid synthesis of (±)-FTC/3TC from an achiral tartrate ester.
Systemic and intestinal pharmacokinetics of methotrexate in patients with inflammatory bowel disease (1999)

Subcutaneous methotrexate was well absorbed and distributed to the site of the lesions in patients with inflammatory bowel disease. Methotrexate was concentrated intracellularly in blood and in the rectum. The methotrexate concentration in the rectal mucosa remained within a pharmacologically active range throughout the dosing interval. The findings represent a pharmacologic explanation for the sustained efficacy of weekly methotrexate therapy.
Reliable multicast for flat hierarchy networks based on adaptive air caching (2003)

The evolution of satellite networks in the commercial and military world has pushed the research community towards the solution of important problems related to this kind of network. One of those important problems is how to design an efficient reliable multicast protocol in a network where there is no hierarchy involved, and the link presents characteristics like high propagation delay and high BER. The existing reliable multicast protocols cannot be applied in the case of flat hierarchy networks, since those are based on intermediate receivers and local recovery techniques. So, we introduce the air caching technique, which serves as a fast access memory that is realized on the air and contains packets for the recovery of corrupted or erroneous data packets at the receivers. In this paper we present some of the protocols that we designed and are based on air caching combined with FEC and ARQ. In the past we have presented protocols that are based on those techniques but the characteristics of the air cache were constant. In this paper we propose RM protocols, which are based on adaptive air caching, where the size and/or content of the air cache change dynamically based on feedback information. Our goal is to improve the delay and/or bandwidth usage characteristics of the nonadaptive air cache RM protocols.
Synthesis of alkenyl 3-hydroxy-2-naphthoates (2016)

Esterification of 3-hydroxy-2-naphthoic acid with homologous primary and secondary alkenyl alcohols with different chain lengths in the presence of N,N'-carbonyldiimidazole (CDI) and 1,8-diazabicyclo[ 5.4.0]undec-7-ene (DBU) in N,N-dimethylformamide gave the corresponding esters.
Development of coupling controlled polymerizations by adapter-ligation in mate-pair sequencing for detection of various genomic variants in one single assay (2019)

The diversity of disease presentations warrants one single assay for detection and delineation of various genomic disorders. Herein, we describe a gel-free and biotin-capture-free mate-pair method through coupling Controlled Polymerizations by Adapter-Ligation (CP-AL). We first demonstrated the feasibility and ease-of-use in monitoring DNA nick translation and primer extension by limiting the nucleotide input. By coupling these two controlled polymerizations by a reported non-conventional adapter-ligation reaction 3' branch ligation, we evidenced that CP-AL significantly increased DNA circularization efficiency (by 4-fold) and was applicable for different sequencing methods but at a faction of current cost. Its advantages were further demonstrated by fully elimination of small-insert-contaminated (by 39.3-fold) with a ∼50% increment of physical coverage, and producing uniform genome/exome coverage and the lowest chimeric rate. It achieved single-nucleotide variants detection with sensitivity and specificity up to 97.3 and 99.7%, respectively, compared with data from small-insert libraries. In addition, this method can provide a comprehensive delineation of structural rearrangements, evidenced by a potential diagnosis in a patient with oligo-atheno-terato-spermia. Moreover, it enables accurate mutation identification by integration of genomic variants from different aberration types. Overall, it provides a potential single-integrated solution for detecting various genomic variants, facilitating a genetic diagnosis in human diseases.
The association between genetic variants in hMLH1 and hMSH2 and the development of sporadic colorectal cancer in the Danish population (2008)

None of the variants in hMLH1 and hMSH2 analyzed in the present study were highly associated with colorectal cancer in the Danish population. High linkage disequilibrium in the genomic regions covering hMLH1 and hMSH2, indicate that common genetic variants in the two genes in general are not involved in the development of sporadic colorectal cancer. Nevertheless, some of the rare unclassified variants in hMLH1 and hMSH2 might be involved in the development of colorectal cancer in the families where they were originally identified.