gebhart/patrepeval huggingface dataset:
Development of dsRNA as a Sustainable Bioinsecticide: From Laboratory to Field (2021)

Foliar-applied double stranded ribonucleic acid (dsRNA) is a new mode of action biopesticide for crop protection against insects. Orally delivered dsRNA can be designed to specifically initiate RNA interference (RNAi) to downregulate mRNA for essential gene sequences unique to target insect pests. The stringent requirement for sequence specificity results in RNAi-mediated control of pests while avoiding negative impacts on non-target organisms. GreenLight Biosciences’ proprietary cell free RNA synthesis platform provides a breakthrough process for cost-effective manufacture of large-scale quantities of dsRNA for commercial field application. GreenLight Biosciences uses its RNA platform to produce the first sprayable dsRNA bioinsecticide product targeting the Colorado potato beetle (CPB), Leptinotarsa decemlineata. Double stranded RNA homologous to the coding sequence for the CPB proteasome subunit beta type-5 (PSMB5) gene was characterized for biological efficacy and target gene knock-down in laboratory and greenhouse experiments. Field studies in potato-growing regions across the United States demonstrated the ability of GreenLight’s CPB product to provide protection against CPB feeding damage equivalent to traditional chemical products. Low persistence under field settings and sequence-based evidence for lack of non-target effects support the long-term sustainability profile of PSMB5 dsRNA. The PSMB5 dsRNA for control of CPB was given the active ingredient common name of Ledprona. Cost effective production of dsRNA will enable commercialization of Ledprona and additional new products with improved environmental safety profiles.
Multiple Biological Activities of Human Interleukin-1 (1987)

Interleukin-1 (IL-1) is a polypeptide product of various cells which mediates host responses to infection and injury. Its most dramatic biological property is its ability to induce arachidonate metabolites in a variety of cells including PGE-2 in brain, fibroblasts, synovial cells and chrondrocytes; in addition, IL-1 induces lipoxygenase products in lymphocytes and other cells. In order to fight life-threatening microbial invasion or localize tissue injury, mammals have developed a large number of varied responses which signal the onset of disease and trigger appropriate defensive measures. The responses are called “acute phase” responses because they are often observed within hours following the injury or initiation of infection. The metabolic and hematological responses can be substantial and are frequently costly to the host especially when they persist and become chronic components of the disease. IL-1 is one of the body’s key mediators of acute responses to microbial invasion, inflammation, immunological reaction and tissue injury.
Improved super-orthogonal space-time trellis codes for fast Rayleigh fading channels (2008)

For fast Rayleigh fading channels, the performance of super-orthogonal space-time trellis codes (SOSTTCs) is analysed and a new code design process is developed. A binary phase shift keying design example is presented. Simulation results and transfer function upper bounds show that the proposed SOSTTC is superior to the previous work.
Simple deep sequencing-based post-remission MRD surveillance predicts clinical relapse in B-ALL (2018)

This pilot proof-of-concept study illustrates the clinical utility of a simple, sensitive, and clinically feasible MRD detection platform in post-remission NGS-based MRD surveillance and early relapse detection in B-ALL patients.
The Malassezia Genus in Skin and Systemic Diseases (2012)

In the last 15 years, the genus Malassezia has been a topic of intense basic research on taxonomy, physiology, biochemistry, ecology, immunology, and metabolomics. Currently, the genus encompasses 14 species. The 1996 revision of the genus resulted in seven accepted taxa: M. furfur, M. pachydermatis, M. sympodialis, M. globosa, M. obtusa, M. restricta, and M. slooffiae. In the last decade, seven new taxa isolated from healthy and lesional human and animal skin have been accepted: M. dermatis, M. japonica, M. yamatoensis, M. nana, M. caprae, M. equina, and M. cuniculi. However, forthcoming multidisciplinary research is expected to show the etiopathological relationships between these new species and skin diseases. Hitherto, basic and clinical research has established etiological links between Malassezia yeasts, pityriasis versicolor, and sepsis of neonates and immunocompromised individuals. Their role in aggravating seborrheic dermatitis, dandruff, folliculitis, and onychomycosis, though often supported by histopathological evidence and favorable antifungal therapeutic outcomes, remains under investigation. A close association between skin and Malassezia IgE binding allergens in atopic eczema has been shown, while laboratory data support a role in psoriasis exacerbations. Finally, metabolomic research resulted in the proposal of a hypothesis on the contribution of Malassezia-synthesized aryl hydrocarbon receptor (AhR) ligands to basal cell carcinoma through UV radiation-induced carcinogenesis.
Carbon monoxide hydrogenation using manganese oxide-based catalysts: effect of operating conditions on alkene selectivity (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarbon monoxide hydrogenation using manganese oxide-based catalysts: effect of operating conditions on alkene selectivityRichard G. Copperthwaite, Graham J. Hutchings, Mark Van der Riet, and Jeremy WoodhouseCite this: Ind. Eng. Chem. Res. 1987, 26, 5, 869–874Publication Date (Print):May 1, 1987Publication History Published online1 May 2002Published inissue 1 May 1987https://doi.org/10.1021/ie00065a002RIGHTS & PERMISSIONSArticle Views442Altmetric-Citations32LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (714 KB) Get e-Alerts Get e-Alerts
<title>Compact ArF excimer lasers specific to microlithography and surgery</title> (1997)

High repetition rate operation technology and spectral narrowing technology with compact excimer lasers whose cross-sectional dimensions are around 120 by 120 mm. High repetition rate operation over 1.5 kHz and spectral narrowing to 1 pm are reported. These technologies are essential to promising applications of ArF excimer lasers. High resolution pattern of 0.16 micrometer line and space is demonstrated by an optical laser lithography with the compact ArF excimer laser. The smallest ArF excimer laser specific to the photo-chemical surgery of cornea is also presented.
Interactive CoMP Clustering for Load Balancing and Time Synchronization (2022)

This work aims to address the timing synchronization issue which limits the applicability of coordinated multipoint schemes, specifically joint transmission, in practical wireless networks. Following a brief description of the issue itself, and its repercussions on the network performance, the various conditions/solutions that mitigate this problem are recapped. Following this, we provide the background of the proposed approach to be used for mitigating the timing synchronization issues, namely, common cyclic prefix (CP) technique. Then, a clustering algorithm is proposed aimed at balancing the cell load with timing synchronization as a constraint. In load balancing stage, the first priority is given to users with higher received power and lower number of base stations in the candidate set. The results obtained via simulations indicate that heterogeneous network (HetNet) deployments suffer from timing synchronization when smaller CP duration is used, and this performance degradation can be resolved quite effectively using the common CP configuration.
Word clustering for a word bi-gram model (1998)

In this paper we describe a word clustering method for class-based n-gram model. The measurement for clustering is the entropy on a corpus different from the corpus for n-gram model estimation. The search method is based on the greedy algorithm. We applied this method to a Japanese EDR corpus and English Penn Treebank corpus. The perplexities of word-based n-gram model on EDR corpus and Penn Treebank are 153.1 and 203.5 respectively. And Those of class-based n-gram model, estimated through our method, are 146.4 and 136.0 respectively. The result tells us that our clustering methods is better than the Brown’s method and the Ney’s method called leaving-one-out.
Optical wireless communications in industrial production environments (2017)

We present broadband 8×6 MIMO channel measurements in an industrial production environment. Motivated by the observation of sudden fades with 10-20 dB due to slight rotations/translational movements and thus line-of-sight blockage, antenna diversity schemes are evaluated in transmission experiments for increased robustness.
Photo toxicity of Zinc Oxide Nanowires in Human Melanoma and Fibroblast Cells (2011)

In nanoscience and nanotechnology, zinc oxide (ZnO) is gaining much research attention due to direct wide band gap (3.3 eV), large exciton binding energy (60 meV), and deep level defects emissions that cover the whole visible range. ZnO nanorods (NRs) in comparison to normal bio molecules and large surface area to volume ratio, allow them to interact within the cell thus are used as convincing intracellular carriers of photosensitizers. Vertical NRs are wave guiding cavities enhancing the light extraction efficiency from devices and are stable photosensitizing agents with their biophotonic, and biodegradation properties, therefore are appealing candidates for the photodynamic therapy of cancer. The heterojunction LEDs of ZnO NRs/p-GaN are best choice to take the advantage of GaN ideal blue-light emission and fabricated LEDs explore the potential of white LEDs with superior performance. The main objective of this thesis is not only to fabricate ZnO NRs/p-GaN, or ZnO nanotubes (ZNTs)/p-GaN heterostructures, but also to investigate their optical properties for photodynamic therapy. These LEDs have showed enhanced EL intensity covering the visible band (425–750 nm). ZnO nanorods are grown on the borosilicate glass capillaries (0.7 μm diameter) and then conjugated with photosensitizer. Such glass capillaries having ZnO nanorods complex with photosensitizer on them are used as pointer for intracellular mediated photochemistry in cells to achieve their necrosis. Mitochondrial staining of melanoma and foreskin fibroblast cells was done by Mitotracker Red with the aim of targeting the specific organelle with the prepared ZnO nanowires (NWs) Femtotip to see ROS production. Cytotoxic effects of nanometallic oxides e.g. ZnO-NRs, MnO2 NRs, and Fe2O3 NPs individually and their ligands with photosensitizers in osteosarcoma (U2OS) cells are also explored. Thus bare and ligands of nanometallic oxides, with particular focus of ZnO nanowires are having significant and convincing cytotoxic effects via the liberation of reactive oxygen species as well as Zn+2 ions in labeled cells, thus can be assigned as anticancer agents for breast cancer, melanoma cancer and osteosarcoma cells.
MIIT: International in-situ testing of simulated HLW forms--preliminary analyses of SRL 165/TDS waste glass and metal systems (1989)

The first in-situ tests involving burial of simulated high-level waste (HLW) forms conducted in the United States were started on July 22, 1986. This effort, called the Materials Interface Interactions Tests (MIIT), comprises the largest, most cooperative field testing venture in the international waste management community. Included in the study are over 900 waste form samples comprising 15 different systems supplied by seven countries. Also included are almost 300 potential canister or overpack metal samples of 11 different metals along with more than 500 geologic and backfill specimens. There are a total of 1926 relevant interactions that characterize this effort which is being conducted in the bedded salt site at the Waste Isolation Pilot Plant (WIPP), near Carlsbad, New Mexico.
cis-1-Benzoyl-2-(2-benzyloxy-5-chlorophenyl)-4-chloropyrrolidine-2-carbonitrile (2007)

In the title compound, C25H20Cl2N2O2, which is a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse transcriptase inhibitor (NNRTI), the pyrrolidine ring has as envelope conformation. Centrosymmetric dimers of mol­ecules appear to associate via short N⋯Cl inter­actions [3.205 (2) Å].
Abstract 1398: Targeting novel co-activators of androgen receptor in castration resistant prostate cancer (2014)

Abstract Resistance to androgen deprivation therapies and increased androgen receptor (AR) activity are major drivers of castrate resistant prostate cancer (CRPC), an advanced and frequently lethal form of this disease. Substantial prior work has focused on targeting AR directly; however, the identification and therapeutic targeting of co-activators of AR signaling remains an underexplored area of potential clinical significance. Here we demonstrate that the MLL complex acts as a co-activator of AR signaling. AR directly interacts with the sub-unit menin to recruit MLL and its complex to AR target genes. Inhibition of the menin-MLL interaction can block AR signaling and inhibit the formation of castration resistant tumors in vivo. Furthermore, we find that menin is up-regulated in localized and metastatic prostate cancer and high menin expression correlates with poor overall survival. Taken together our study identifies a novel co-activator complex of AR that can be targeted in CRPCs. Citation Format: Rohit Malik, Amjad P. Khan, John R. Prensner, Matthew K. Iyer, Dmitry Borkin, Xiaoju Wang, Xia Jiang, Shruthi Subramaniam, Yang Shi, Rachell Stender, Yi-Mi Wu, Xuhong Cao, Jolanta Grembecka, Tomasz Cierpicki, Arul Chinnaiyan. Targeting novel co-activators of androgen receptor in castration resistant prostate cancer. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 1398. doi:10.1158/1538-7445.AM2014-1398
Restaurants by Design (2006)

This book offers a sumptuous look at some of the most innovative restaurant designs today. It features Karim Rashid - Morimoto Restaurant in Philadelphia, Nooch Restaurant - Nooch Singapore, The Rockwell Group - Nodu 57 in New York and many more. Here are the latest and most creative approaches to restaurant design today. Featuring exciting places from around the world, this fascinating guide explores the collaborative efforts between chefs and architects, examining the particular design approach used in each of the eateries, from the layout and structure of the physical space to designs for the dishes, linens, lighting and furnishings, and how they compliment and highlight the food.
COMPARISON OF INTRAVESICAL BOTULINUM TOXIN A INJECTIONS PLUS HYDRODISTENTION AND HYDRODISTENTION ALONE FOR TREATMENT OF REFRACTORY INTERSTITIAL CYSTITIS (2009)

You have accessJournal of Urology1 Apr 2009COMPARISON OF INTRAVESICAL BOTULINUM TOXIN A INJECTIONS PLUS HYDRODISTENTION AND HYDRODISTENTION ALONE FOR TREATMENT OF REFRACTORY INTERSTITIAL CYSTITIS Hann-Chorng Kuo and Michael B Chancellor Hann-Chorng KuoHann-Chorng Kuo More articles by this author and Michael B ChancellorMichael B Chancellor More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(09)60061-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "COMPARISON OF INTRAVESICAL BOTULINUM TOXIN A INJECTIONS PLUS HYDRODISTENTION AND HYDRODISTENTION ALONE FOR TREATMENT OF REFRACTORY INTERSTITIAL CYSTITIS." The Journal of Urology, 181(4S), pp. 17–18 © 2009 by American Urological AssociationFiguresReferencesRelatedDetails Volume 181 Issue 4S April 2009 Page: 17-18 Advertisement Copyright & Permissions© 2009 by American Urological AssociationMetrics Author Information Hann-Chorng Kuo More articles by this author Michael B Chancellor More articles by this author Expand All Advertisement PDF downloadLoading ...
Pig ICN recording v1 (2019)

Yorshire pigs are anthesized for ICN/ neuromodulation recodings. Montior hemodynics mid-sternotomy
Left bundle branch block during pregnancy as a sign of imminent peripartum cardiomyopathy (2011)

We describe the development of peripartum cardiomyopathy (PPCM) in a 32-year-old woman. Because of a known cardiomyopathy of her mother, she obtained five cardiologic examinations from the gestational age of weeks 16–38 with ECG and echocardiograms. Except that the ECG showed a complete left bundle branch block (LBBB), the patient experienced no cardiac disorder throughout her pregnancy ( Panels A and B , Supplementary material online). After spontaneous and uncomplicated vaginal delivery of an eutrophic daughter, she was discharged from hospital in a healthy condition. Six months later, …
Chemically tunable cationic polymer-bonded magnetic nanoparticles for gene magnetofection (2013)

This study evaluates the efficiency of novel non-viral vectors consisting of super paramagnetic iron oxide nanoparticles functionalized with the chemically tunable cationic polymer for in vitro gene magnetofection. The cationic polymer, poly(vinyl pyridinium alkyl halide), with a reactive alkoxysilyl group at one terminal of the polymer (VPCm<sub>n</sub>, m = length of the side chain and n = polymerization degree), was grafted onto the surface of iron oxide nanoparticles through a silane coupling reaction. The VPCm<sub>n</sub> grafted-magnetic nanoparticles (Mag-VPCm<sub>n</sub>) were quaternized with various alkyl halides such as methyl iodide (m = 1), ethyl bromide (m = 2), butyl bromide (m = 4), hexyl bromide (m = 6) and octyl bromide (m = 8). Mag-VPCm<sub>n</sub> quaternized with a shorter alkyl chain (m = 1, 2, 4 and 6) were water dispersible, but that quaternized with a longer alkyl chain (m = 8) was precipitated in water. The surface of water dispersible Mag-VPCm<sub>n</sub>s was positively charged in pH ranging from 2 to 11, and is stable for more than one month in this pH range. The complexes of Mag-VPCm<sub>n</sub>s and nucleoside molecules with various N/P ratios were evaluated using gel electrophoresis, surface charge (ζ-potential) measurement, and particle size measurement. In vitro transfection experiments were assayed in human embryonic kidney 293 cells (HEK293 cells) using pmaxGFP plasmid as a reporter gene. Gene expression was found to be strongly influenced by the length of the side alkyl chains. Higher transfection efficiencies were observed with longer alkyl chains (C6 > C4 > C2 ≥ C1), indicating that hydrophobic side chains were effective in increasing the transfection efficiency.
Report on ACM sigir workshop on mathematical/formal methods in information retrieval (2002)

No abstract available.
Synthesis of Porous Carbon Supported Palladium Nanoparticle Catalysts By Atomic Layer Deposition: Application for Rechargeable Lithium-O2 Battery (2013)

Abstract not Available.
Low-Temperature Hybrid CMOS Circuits Based on Chalcogenides and Organic TFTs (2011)

In this letter, we demonstrate a fully integrated approach to fabricate cadmium sulfide (CdS)-pentacene complementary metal-oxide-semiconductor (CMOS) digital circuits compatible with flexible electronics. Low-cost and low-temperature chemical bath deposition is used to deposit CdS at 70°C with mobility values >; 10 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> /V·s and threshold voltages around 5 V for fully integrated devices. p-MOS thin-film transistors were fabricated using thermally evaporated pentacene as semiconductor with mobility and threshold voltages in the range of 3×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-2</sup> cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> /V·s and -3 V, respectively. The CMOS integration approach includes six mask levels with a maximum processing temperature of 100°C.
Thermal Scattering Law Evaluations and Progress at NCSU [Slides] (2020)

The presentation discusses the eight new Thermal Scattering Law (TSL) evaluations that have been submitted to the National Nuclear Data Center (NNDC). It explains that evaluations are performed using the NCSU FLASSH code and that NJOY/LEAPR input files are provided to allow for independent testing. The presentation concludes by stating that more evaluations are expected to be submitted before the end of 2020.
Dependence of photoresist dissolution dynamics in alkaline developers on alkyl chain length of tetraalkylammonium hydroxide (2022)

Abstract Extreme ultraviolet (EUV) lithography is already being applied to the high-volume manufacturing of semiconductor devices. Although EUV lithography has enabled fine pitch scaling, such sub-20 nm order fabrication has also imposed the issue of stochastic defects (in the form of randomly generated line bridges and breaks). To resolve such an issue, understanding the development process is essential. In this study, the dissolution dynamics of three types of EUV photoresist were investigated for four types of alkaline developer using a quartz crystal microbalance method to clarify the swelling and dissolution kinetics during photoresist development. In experiments, tetramethylammonium hydroxide (TMAH), tetraethylammonium hydroxide (TEAH), tetrapropylammonium hydroxide (TPAH), and tetrabutylammonium hydroxide (TBAH) aqueous solutions were used as developers. Poly(4-hydroxystyrene) (PHS)-type, acryl-type, and hybrid-type photoresists were examined. The effect of the alkyl chain length of tetraalkylammonium cations depended on the type of photoresist. The dissolution dynamics depended on the combination of types of photoresist and developer.
Morbid Obesity: A Significant Risk Factor for Failure of Two-Stage Revision Total Knee Arthroplasty for Infection (2014)

Morbid obesity significantly increased the risk of subsequent revision, reoperation, and reinfection following two-stage revision total knee arthroplasty for infection. In addition, these patients had worse pain relief and overall function at intermediate-term clinical follow-up. Although two-stage revision should remain a standard treatment for chronic periprosthetic joint infection in morbidly obese patients, increased failure rates and poorer outcomes should be anticipated.