gebhart/patrepeval huggingface dataset:
Interaction second virial coefficients and binary interaction parameters for the CO2 C2H6 systems between 250 and 300 K (1982)

Abstract We have determined the interaction second virial coefficients ( B 12 ) for the CO 2  C 2 H 6 system between 250 and 300K using a Burnett‐isochoric apparatus. The technique follows a procedure suggested by Hall and Eubank (1973) and extended by Holste et al. (1980). Combined errors for B 12 are within 1.2 cm 3 /mol. In addition, values for the binary interaction parameter k 12 calculated from our B 12 values show difinite temperature dependence.
The male sterility-associated pcf gene and the normal atp9-1 gene in Petunia are located on different mitochondrial DNA molecules. (1991)

A mitochondrial DNA (mtDNA) region termed the S-pcf locus has previously been correlated with cytoplasmic male sterility (CMS) in Petunia. In order to understand the relationship of the S-pcf locus to homologous sequences found elsewhere in mtDNAs of both CMS and fertile lines, the structure of the mitochondrial genome of CMS Petunia line 3688 was determined by cosmid walking. The S-pcf locus, which includes the only copies of genes for NADH dehydrogenase subunit 3 (nad3) and small ribosomal subunit protein 12 (rps12) was found to be located on a circular map of 396 kb, while a second almost identical circular map of 407 kb carries the only copies of the genes for 18S and 5S rRNA (rrn18 and rrn5), the only copy of a conserved unidentified gene (orf25), and the only known functional copy of atp9. Three different copies of a recombination repeat were found in six genomic environments, predicting sub-genomic circles of 277, 266 and 130 kb. The ratio of atp9 to S-pcf mtDNA sequences was approximately 1.5 to 1, indicating that sub-genomic molecules carrying these genes differ in abundance. Comparison of the mtDNA organization of the CMS line with that of the master circle of fertile Petunia line 3704 reveals numerous changes in order and orientation of ten different sectors.
Genetic and phenotypic attributes of splenic marginal zone lymphoma (2021)

Splenic marginal zone B-cell lymphoma (SMZL) is a heterogeneous clinico-biological entity. The clinical course is variable, multiple genes are mutated with no unifying mechanism, and essential regulatory pathways and surrounding microenvironments are diverse. We sought to clarify the heterogeneity of SMZL by resolving different subgroups and their underlying genomic abnormalities, pathway signatures, and microenvironment compositions to uncover biomarkers and therapeutic vulnerabilities. We studied 303 SMZL spleen samples collected through the IELSG46 multicenter international study (NCT02945319) by using a multiplatform approach. We carried out genetic and phenotypic analyses, defined self-organized signatures, validated the findings in independent primary tumor metadata and in genetically modified mouse models, and determined correlations with outcome data. We identified 2 prominent genetic clusters in SMZL, termed NNK (58% of cases, harboring NF-κB, NOTCH, and KLF2 modules) and DMT (32% of cases, with DNA-damage response, MAPK, and TLR modules). Genetic aberrations in multiple genes as well as cytogenetic and immunogenetic features distinguished NNK- from DMT-SMZLs. These genetic clusters not only have distinct underpinning biology, as judged by differences in gene-expression signatures, but also different outcomes, with inferior survival in NNK-SMZLs. Digital cytometry and in situ profiling segregated 2 basic types of SMZL immune microenvironments termed immune-suppressive SMZL (50% of cases, associated with inflammatory cells and immune checkpoint activation) and immune-silent SMZL (50% of cases, associated with an immune-excluded phenotype) with distinct mutational and clinical connotations. In summary, we propose a nosology of SMZL that can implement its classification and also aid in the development of rationally targeted treatments.
Vapor explosion in the RIA-ST-4 experiment. [PWR; BWR] (1980)

A concern in assuring the safety of commercial light water reactors (LWRs) is whether core overheating, during which molten fuel is produced, can lead to massive vaporization of the coolant and shock pressurization of the system due to an energetic molten fuel-coolant interaction (MFCI). The RIA-ST-4 experiment was one of four scoping tests in the Reactivity Initiated Accident (RIA) Test Series which is being conducted in the Power Burst Facility (PBF) to define an energy deposition failure threshold and to determine modes and consequences of fuel rod failure during a postulated boiling water reactor (BWR) control rod drop accident.
Steganography using Gibbs random fields (2010)

Many steganographic algorithms for empirical covers are designed to minimize embedding distortion. In this work, we provide a general framework and practical methods for embedding with an arbitrary distortion function that does not have to be additive over pixels and thus can consider interactions among embedding changes. The framework evolves naturally from a parallel made between steganography and statistical physics. The Gibbs sampler is the key tool for simulating the impact of optimal embedding and for constructing practical embedding algorithms. The proposed framework reduces the design of secure steganography in empirical covers to the problem of finding suitable local potentials for the distortion function that correlate with statistical detectability in practice. We work out the proposed methodology in detail for a specific choice of the distortion function and validate the approach through experiments.
Effect of alloying elements on the interfacial shear strength between CVD-SiC fiber and aluminum. (1992)

The effects of alloying elements on the interfacial shear strength were measured by pull-out method, and the critical fiber length for reinforcing composite was evaluated. The interfacial shear strength was high for SCS-6 fiber which was dipped into liquid aluminum alloy containing silicon or titanium with high affinity to carbon. The critical fiber length was estimated as 3.3 to 3.5mm. Aluminum alloys containing such surface active element as magnesium or lithium, the interfacial shear strength for SCS-6 fiber was low and its critical fiber length was longer than 20mm. This is because magnesium atoms adsorbed on the carbon rich layer and disturbed the binding reaction between aluminum and carbon. It was also found at both dipping lengths, especially at 1mm of SCS-6 fiber in Al-5%Mg alloy, that, after middle stage of dipping time, the interfacial shear strength increased, due to the formation of crater like erosion on the surface of carbon rich layer, resulting in decrease in critical fiber length as 6.5mm. These craters may act not as a notch but as an anchor.
CARF Binds to Three Members (ARF, p53, and HDM2) of the p53 Tumor‐Suppressor Pathway (2007)

The INK4a locus (chromosome 9p21) encodes two structurally distinct tumor-suppressor proteins, p16(INK4a) and the alternative reading frame protein, ARF (p19(ARF) in mouse and p14(ARF) in human). Each of these proteins has a major role in cell cycle control and senescence pathways. We originally identified a novel collaborator of ARF, CARF, from a two-hybrid interactive screen using p19(ARF) as bait and found that CARF interacts with ARF in the perinucleolar region and activates p53 function. In the absence of ARF, it interacts with p53 directly leading to ARF-independent enhancement of p53 function and in turn undergoes a negative feedback regulation. Very recently, we found that CARF interacts with HDM2 and undergoes degradation by an HDM2-dependent proteasome pathway. CARF may exert a vital control on p53-HDM2-p21(WAF1) pathway that is central to the cell cycle control, senescence, and DNA damage response of human cells.
Effect of strain and barrier composition on the polarization of light emission from AlGaN/AlN quantum wells (2012)

For AlGaN-based multi-quantum-well light emitters grown on c-plane substrates there is a tendency for the polarization of the emitted light to switch from transverse electric (TE) polarization to transverse magnetic (TM) polarization as the wavelength decreases. This transition depends on various factors that include the strain in the quantum well. Experimental results are presented that illustrate the phenomenon for nitride light emitting diodes (LEDs) grown on sapphire and on bulk AlN. Model calculations are presented which quantify the dependence of the TE/TM switch on the quantum well strain and the Al composition in the barriers surrounding the well.
Wavelength multicasting in silicon photonic nanowires (2010)

We demonstrate a scalable, energy-efficient, and pragmatic method for high-bandwidth wavelength multicasting using FWM in silicon photonic nanowires. We experimentally validate up to a sixteen-way multicast of 40-Gb/s NRZ data using spectral and temporal responses, and evaluate the resulting data integrity degradation using BER measurements and power penalty performance metrics. We further examine the impact of this wavelength multicasting scalability on conversion efficiency. Finally, we experimentally evaluate up to a three-way multicast of 160-Gb/s pulsed-RZ data using spectral and temporal responses, representing the first on-chip wavelength multicasting of pulsed-RZ data.
Identification of Binding Sites for Myeloid Differentiation Primary Response Gene 88 (MyD88) and Toll-like Receptor 4 in MyD88 Adapter-like (Mal) (2013)

Upon activation, Toll-like receptor 4 (TLR4) binds adapter proteins, including MyD88 (myeloid differentiation primary response gene 88) and Mal (MyD88 adapter-like) for its signal transduction. TLR4 and the adapter proteins each contain a Toll/Il-1 receptor domain (TIR domain). In this study we used random mutagenesis and the mammalian two-hybrid method MAPPIT (mammalian protein-protein interaction trap) to identify mutations in Mal that disrupt its interaction with TLR4 and/or MyD88. Our study shows that four potential binding sites and the AB-loop in the Mal TIR domain all contribute to formation of the TLR4-Mal-MyD88 complex. Mutations in the symmetrical back-to-back Mal homodimer interface affect Mal homodimerization and interaction with MyD88 and TLR4. Our data suggest that Mal dimerization may lead to formation of potential binding platforms on the top and the side of the Mal dimer that bind MyD88 or TLR4. Mutations that affect the interaction of Mal with MyD88 also affect NF-κB activation induced by Mal overexpression. In MAPPIT, co-expression of the MyD88 TIR domain enhances Mal dimerization and Mal binding to TLR4. Similarly, co-expression of Mal and the MyD88 TIR domain strongly promotes dimerization of the TLR4 intracellular domain in MAPPIT. The different types of TIR-TIR interactions in the TLR4-Mal-MyD88 complex thus show cooperative binding in MAPPIT. We present plausible models for the TIR-TIR interactions in the TLR4-Mal-MyD88 complex.
Beamforming Training for IEEE 802.11 ay Millimeter Wave Systems (2018)

IEEE 802.11ay is a standard that enables enhanced throughput for IEEE 802.11 systems operating in the license-exempt 60 GHz band. By specifying advanced physical layer (PHY) features, improved channel access, and enhanced beamforming training, IEEE 802.11ay supports a maximum data rate of 100 Gb/s, making it a standard of great interest for applications as diverse as virtual reality, high density/throughput networking, and backhaul. In this paper, we provide a description and discussion of two important beamforming training procedures defined in IEEE 802.11ay, namely beam refinement protocol (BRP) transmit sector sweep (TXSS) and asymmetric beamforming training. Because these procedures build upon concepts defined in IEEE 802.11ad, we also examine two legacy beamforming training procedures: Sector-level sweep (SLS) and BRP. PHY definitions relevant to beamforming training are also reviewed.
microRNAs Promoting Growth of Gastric Cancer Xenografts and Correlation to Clinical Prognosis (2021)

The annual death toll for gastric cancer is in the range of 700,000 worldwide. Even in patients with early-stage gastric cancer recurrence within five years has been observed after surgical resection and following chemotherapy with therapy-resistant features. Therefore, the identification of new targets and treatment modalities for gastric cancer is of paramount importance. In this review we focus on the role of microRNAs with documented efficacy in preclinical xenograft models with respect to growth of human gastric cancer cells. We have identified 31 miRs (-10b, -19a, -19b, -20a, -23a/b, -25, -27a-3p, -92a, -93, -100, -106a, -130a, -135a, -135b-5p, -151-5p, -187, -199-3p, -215, -221-3p, -224, -340a, -382, -421, -425, -487a, -493, -532-3p, -575, -589, -664a-3p) covering 26 different targets which promote growth of gastric cancer cells in vitro and in vivo as xenografts. Five miRs (miRs -10b, 151-5p, -187, 532-3p and -589) additionally have an impact on metastasis. Thirteen of the identified miRs (-19b, -20a/b, -25, -92a, -106a, -135a, -187, -221-3p, -340a, -421, -493, -575 and -589) have clinical impact on worse prognosis in patients.
AIM Photonics - What merging photonics with nano-electronics will do (2016)

The National Network for Manufacturing Innovation (NNMI) is a network of research institutes in the United States that focuses on developing and commercializing manufacturing technologies through public-private partnerships between U.S. industry, universities, and federal government agencies. As one of the early institutes, the American Institute for Manufacturing integrated Photonics (AIM Photonics) was officially announced in July 2015. This Institute is focused on developing an end-to-end photonic integrated circuit (PIC) ecosystem in the U.S., including domestic foundry access, integrated design tools, automated packaging, assembly and test, and workforce development.
Lipases and Related Molecules in Cancer (2010)

Lipases are enzymes that catalyze the hydrolysis of lipids. Based on protein structures and sequences, lipases can be classified into different protein families. The majority of conventional mammalian lipases are members of the protein super-families of serine esterases and alpha-beta hydrolases. Differential expression of lipases and related alpha-beta hydrolases in tumor cells has been observed. The physiological or patho-physiological functions of these tumor related enzymes are largely unknown. However, lipases are not only involved in energy metabolism but also in the metabolism of bioactive molecules, e.g. phosphatidic acid or arachidonic acid, suggesting that tumor-specifically expressed lipases might be interesting targets for the development of future treatment strategies. Moreover, independent of the patho-physiological function, tumor associated lipases can serve as targets for immunological treatment strategies. In addition, lipases with exclusive expression in single tumor entities can serve as potential diagnostic targets.
Improvement of the thermal properties of semiconductor chips at 850 nm (poster) (2013)

International audience
Asymptotic analysis of blind cyclic correlation-based symbol-rate estimators (2002)

This paper considers the problem of blind symbol rate estimation of signals linearly modulated by a sequence of unknown symbols. Oversampling the received signal generates cyclostationary statistics that are exploited to devise symbol-rate estimators by maximizing in the cyclic domain a (possibly weighted) sum of modulus squares of cyclic correlation estimates. Although quite natural, the asymptotic (large sample) performance of this estimator has not been studied rigorously. The consistency and asymptotic normality of this symbol-rate estimator is established when the number of samples N converges to infinity. It is shown that this estimator exhibits a fast convergence rate (proportional to N/sup -3/2/), and it admits a simple closed-form expression for its asymptotic variance. This asymptotic expression enables performance analysis of the rate estimator as a function of the number of estimated cyclic correlation coefficients and the weighting matrix. A justification for the high performance of the unweighted estimator in high signal-to-noise scenarios is also provided.
Accuracy improvement in Cranio-Maxillofacial soft tissue simulation using a muscle embedded meshing approach (2013)

In the presented paper, we propose to improve the state-of-the-art approach for Cranio-Maxillofacial (CMF) soft tissue simulation by considering a new image-based meshing approach that accurately models the interface between different tissue types. The proposed approach has been initially evaluated on soft tissue deformations of four patients undergoing CMF surgery using post-operative CT scans. The results indicate improved prediction and robustness of the surgical planning outcome when compared to the state-of-the-art method while decreasing the simulation time.
Mitigation of Condensate Banking Using Thermochemical Treatment: Experimental and Analytical Study (2019)

Condensate banking is a common problem in tight gas reservoirs because it diminishes the gas relative permeability and reduces the gas production rate significantly. CO2 injection is a common and very effective solution to mitigate the condensate damage around the borehole in tight gas reservoirs. The problem with CO2 injection is that it is a temporary solution and has to be repeated frequently in the field in addition to the supply limitations of CO2 in some areas. In addition, the infrastructure required at the surface to handle CO2 injection makes it expensive to apply CO2 injection for condensate removal. In this paper, a new permanent technique is introduced to remove the condensate by using a thermochemical technique. Two chemicals will be used to generate in situ CO2, nitrogen, steam, heat, and pressure. The reaction of the two chemicals downhole can be triggered either by the reservoir temperature or a chemical activator. Two chemicals will start reacting and produce all the mentioned reaction products after 24 h of mixing and injection. In addition, the reaction can be triggered by a chemical activator and this will shorten the time of reaction. Coreflooding experiments were carried out using actual condensate samples from one of the gas fields. Tight sandstone cores of 0.9 mD permeability were used. The results of this study showed that the thermochemical reaction products removed the condensate and reduced its viscosity due to the high temperature and the generated gases. The novelty in this paper is the creation of micro-fractures in the tight rock sample due to the in-situ generation of heat and pressure. These micro-fractures reduced the capillary forces that hold the condensate and enhanced the rock relative permeability. The creation of micro-fractures and in turn the reduction of the capillary forces can be considered as permanent condensate removal.
Blazed binary diffractive gratings with antireflection coating for improved operation at 10.6 μm (2004)

We report on the design fabrication and characterization a 3-period grating composed of subwavelength ridges of progressively varying widths for operation at 10.6 µm. The grating is blazed into the first transmitted order (an efficiency of 80% is measured) under TM polarization and over a broad range of angles of incidence. The fabrication involves contact photolithography, reactive-ion etching, and an evaporation deposition over the etched structure. The result validates the use of photolithography, a low-cost technology, for the manufacture of efficient blazed binary diffractive elements for thermal imaging (the 8- to 12-µm IR band).
110. Performance Analysis, Calibration, and Testing of Micro Processor based Digital Fault Recorder with Phasor Measurement Unit (PMU) (2007)

With the increase interest in the Wide Area Monitoring, Control and Disturbance Analysis, and to minimize the future black outs caused due to the cascade tripping, there is a growing interest in the microprocessor based relays and disturbance recorders to provide an additional Phaser Measurement Unit (PMU) measurement and reporting. The recent IEEE C37.118 standard on the synchrophasors outlines certain stringent requirements in terms of how to precisely measure the phase angle with respect to the global time reference – the coordinated universal time (UTC), and how to report the phasor information. The standard also specifies the Total Vector Error (TVE) allowed in evaluating the phasor for different compliance level to allow interoperability between different vendor PMUs. The purpose of this paper is to discuss the calibration, testing and performance analysis of a Micro Processor Based Digital Fault Recorder (DFR) with a PMU. The analysis is carried out as per the C37.118 for different compliance levels. The paper discusses various challenges encountered in calibrating the PMU, and comparative analysis of different manufacturers test set and how to carry out the calibration process. Sources of errors and their effect on the PMU reporting will also be discussed. The DFR described in this investigation is a multi time frame recording system used to monitor electrical power systems. It can record up to 36 analog channels and 64 digital (status) channels and store up to 1000 recordings.
Efficient Gene Targeting in Maize using Inducible CRISPR-Cas9 and Marker-Free Donor Template (2020)

Abstract CRISPR-Cas9 is a powerful tool for generating targeted mutations and genomic deletions. However, precise gene insertion or sequence replacement remains a major hurdle before application of CRISPR-Cas9 technology is fully realized in plant breeding. Here we report high frequency, selectable marker-free intra-genomic gene targeting (GT) in maize. Heat shock-inducible Cas9 was used for generating targeted double-strand breaks (DSBs) and simultaneous mobilization of the donor template from pre-integrated T-DNA. The construct was designed such that release of the donor template and subsequent DNA repair activated expression of the selectable marker gene within the donor locus. This approach generated up to 4.7% targeted insertion of the donor sequence into the target locus in T0 plants, with up to 86% detected donor template release and 99% mutation rate were observed at the donor loci and the genomic target site, respectively. Unlike previous in planta or intra-genomic homologous recombination reports, that required multiple generations and extensive screening, our method provides non-chimeric, heritable GT in the T0 generation.
6G Vision: An Ultra-Flexible Perspective (2020)

The upcoming sixth generation (6G) communications systems are expected to support an unprecedented variety of applications, pervading every aspect of human life. It is clearly not possible to fulfill the service requirements without actualizing a plethora of flexible options pertaining to the key enabler technologies themselves. At that point, this work presents an overview of the potential 6G key enablers from the flexibility perspective, categorizes them, and provides a general framework to incorporate them in the future networks. Furthermore, the role of artificial intelligence and integrated sensing and communications as key enablers of the presented framework is also discussed.
Sensor-less torque control considering contact phase for two-mass system (2018)

This paper considers the contact phase in a sensorless torque control system for a two-mass system. A plant system is a two mass system with an environmental switch. The environmental switch is used for considering unstable contact behavior. The state observer (SOB) and zero-order disturbance observer (ZODOB) are used to estimate the state variable of a plant system. In sensor-less torque control system, the ZODOB has better performance than the SOB. When plant system is not in contact with the environment the estimated value using the SOB is not good for control system. It makes control system becomes instability in some cases. When the ZODOB is fed back to torque control system, the stability of control system is preserved. Experiments are performed to confirm the effectiveness of using the ZODOB in sensor-less torque control system.