gebhart/patrepeval huggingface dataset:
Potential of DMSO as greener solvent for PES ultra‐ and nanofiltration membrane preparation (2018)

ABSTRACT In this article, the performance of polyethersulfone (PES) ultra‐ and nanofiltration membranes, prepared with the non‐toxic solvent dimethyl sulfoxide (DMSO), was investigated. The membranes were prepared by immersion precipitation via phase inversion. Experimental results proved that DMSO is a better alternative to N ‐methyl‐2‐pyrrolidone (NMP) as solvent for PES ultrafiltration membranes as the membranes had a higher permeability and rejection of bovine serum albumin (BSA). An explanation was found based on experimental cloud point data and scanning electron microscopy images showing the morphology. The rejection of BSA and rose Bengal (RB) was proportional to the polymer concentration. On the contrary, the permeability decreased with increasing polymer concentration. For a casting thickness of 250 µm, an optimal balance between permeability and rejection of macromolecules for ultrafiltration was found at 24 wt % PES. The permeability was inversely proportional to the casting thickness, but a small decrease in rejection was observed when lowering the thickness. A good balance between permeability and rejection of RB was found, using a reference nanofiltration membrane of 28.5 wt % PES with 150 µm casting thickness. This membrane achieved a RB rejection of 95.3% and a pure water flux of 2.03 L m −2 h −1 bar −1 . The membrane thickness and polymer concentration did not have a clear influence on the hydrophilicity of the membranes. It can be concluded that DMSO is a benign alternative as compared to traditional solvents such as NMP and also results in better PES membrane performances. DMSO is a perfectly suitable solvent for ultrafiltration applications and has potential to be used for nanofiltration applications. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135 , 46494.
Assessment of endothelial function of large, medium, and small vessels: a unified myograph (2010)

Endothelial dysfunction precedes the development of morphological atherosclerotic changes and can also contribute to lesion development in cardiovascular diseases. Currently, there is a lack of a single method to determine endothelial function of the entire range of vessel dimensions from aorta to arterioles. Here we assessed endothelial function of a large range of size arteries using a unified isovolumic myograph method. The method maintains a constant volume of fluid in the lumen of the vessel during contraction and relaxation, which are characterized by an increase and a decrease of pressure, respectively. Segments of six aortas, six common femoral arteries, and six mesenteric arteries from rats; six carotid arteries from mice; and six coronary and carotid arteries from pigs were used. The endothelium-dependent dose-response vasorelaxation was determined with endothelium-dependent vasodilators while arterial preconstriction was induced with vasoconstrictors at a submaximal dose. The circumferential midtension during vascular reactivity varied from 43.1 ± 7.9 to 2.59 ± 0.46 mN/mm (from large to small arteries), whereas the circumferential midstress showed a much smaller variation from 217 ± 23.5 to 123 ± 15.3 kPa (in the same range of vessels). We also found that overinflation and axial overelongation compromised endothelium-dependent vasorelaxation to underscore the significance of vessel preload. In conclusion, an isovolumic myograph was used to unify arterial vasoreactivity from large to small arteries and shows the uniformity of wall stress and %tension throughout the range of vessel sizes.
PaletteNeRF: Palette-based Appearance Editing of Neural Radiance Fields (2022)

Recent advances in neural radiance fields have enabled the high-fidelity 3D reconstruction of complex scenes for novel view synthesis. However, it remains underexplored how the appearance of such representations can be efficiently edited while maintaining photorealism. In this work, we present PaletteNeRF, a novel method for photorealistic appearance editing of neural radiance fields (NeRF) based on 3D color decomposition. Our method decomposes the appearance of each 3D point into a linear combination of palette-based bases (i.e., 3D segmentations defined by a group of NeRF-type functions) that are shared across the scene. While our palette-based bases are view-independent, we also predict a view-dependent function to capture the color residual (e.g., specular shading). During training, we jointly optimize the basis functions and the color palettes, and we also introduce novel regularizers to encourage the spatial coherence of the decomposition. Our method allows users to efficiently edit the appearance of the 3D scene by modifying the color palettes. We also extend our framework with compressed semantic features for semantic-aware appearance editing. We demonstrate that our technique is superior to baseline methods both quantitatively and qualitatively for appearance editing of complex real-world scenes.
RNA polymerase II terminates transcriptionin vitroin the SV40 origin region (1987)

To begin to study signals on DNA that can cause mammalian RNA polymerase II to terminate transcription, we examined the RNA transcripts produced from a number of different DNA templates in a HeLa whole-cell extract. When transcripts initiating from the strong adenovirus late promoter and extending through the SV40 promoter-replication origin region were analyzed, it was observed that a significant fraction (approximately 75%) were terminated within these SV40 sequences. These transcripts, the 3' ends of which were mapped to several sites within an approximately 200 base pair region, appeared to result from transcription termination, as judged by kinetic and pulse-chase experiments. The possible significance of these findings with respect to SV40 gene expression in particular and transcription termination in general are discussed.
Radar measurement applications of fiber optic links (2003)

Novel applications of fiber-optic delay lines to improve the capability and performance of radar repeater and phase noise test sets are described. Using a 2.25-km-long fiber-optic link, the generation of an ideal target for a radar repeater test set and the measurement of phase noise within 100 Hz of a 9.6-GHz radar carrier signal is demonstrated using a delay line discriminator phase noise test set. FM and AM signal-to-noise measurements were made to determine the performance capability of the 10-GHz modulated fiber-optic links for radar applications.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
The Power of the Question (2008)

RETURN TO ISSUEPREVEditorialNEXTThe Power of the QuestionRICHARD N. ZAREView Author Information Stanford UniversityCite this: Chem. Eng. News 2008, 86, 28, 3Publication Date (Print):July 14, 2008Publication History Published online14 November 2010Published inissue 14 July 2008https://pubs.acs.org/doi/10.1021/cen-v086n028.p003https://doi.org/10.1021/cen-v086n028.p003editorialACS PublicationsCopyright © 2008 AMERICAN CHEMICAL SOCIETY. This publication is available under these Terms of Use. This publication is free to access through this site. Learn MoreArticle Views128Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (93 KB) SUBJECTS:Elements,Molecules,Power,Students Get e-Alerts
[DEMO] “It's a Pirate's Life” AR game (2014)

We present “It's a Pirate's Life” demonstration, an Augmented Reality (AR) game which makes use of real-time 3D reconstruction and tracking using an Intel® RealSense™ camera system embedded in a tablet to build a dynamic game world. Players can play as a pirate ship captain searching for gold on a virtual sea overlaid on the real-world. Real-world objects become part of the play space; islands in the tropical seas which you have to navigate your ships around while avoiding cannon balls to find the treasure. Players control the wind, and hence, direction of sail by moving the tablet around the play space to guide the virtual ship in the real and virtual environment to the pirate gold.
HeapCraft (2015)

We present HeapCraft: an open-source suite of interactive data exploration and visualization tools that allows researchers, server administrators and game designers to analyze and potentially influence player behavior in Minecraft. Our framework includes a telemetry system, several tools for visualizing and representing the collected data, and tools for modifying the game experience in controlled ways. Measures that we use to quantify and visualize player behavior and collaboration have been derived from a large data set containing 3451 player-hours from 908 players and 43 different servers. HeapCraft has been demonstrated on a variety of tasks including player behavior classification, as well as quantifying and improving collaboration of players on Minecraft servers. HeapCraft is freely available and serves to democratize game analytics for the Minecraft community at large.
Alternating copolymer of pyrrole and 2,1,3-benzothiadiazole (1996)

The alternating copolymer of pyrrole and 2,1,3-benzothiadiazole is synthesized together with a set of corresponding oligomers, yielding hydrogen bonded ladder structures with push-pull character and an absorption band up to λmax 700 nm.
Van beeld naar Beslissing (2011)

Door vergrijzing van de bevolking neemt de vraag naar medische zorg aanzienlijk toe. Daarnaast beschikken artsen over steeds meer informatie om de juiste zorg te bepalen. Om voor de toekomst goede en betaalbare zorg te waarborgen, zal deze effectiever en efficiënter moeten worden. Medische beeldanalyse kan hieraan een belangrijke bijdrage leveren. Met behulp van beeldanalyse kunnen artsen beter en sneller de in de medische beelden aanwezige informatie vertalen naar inzicht in het patiëntspecifieke ziektebeeld, om zo beter en sneller beslissingen te nemen over de toe te passen therapie. In deze rede beschrijft Breeuwer de huidige status van cardiovasculaire beeldanalyse algoritmiek en gaat\nhij in op de onderzoeksvragen voor de toekomst. Hij concentreert zich daarbij op de toepassing van cardiovasculaire beeldanalyse algoritmiek op magnetische resonantie beelden.
Two Photoaffinity Analogues of the Tripeptide, Hemiasterlin, Exclusively Label α-Tubulin (2005)

A synthetic analogue of the tripeptide hemiasterlin, designated HTI-286, depolymerizes microtubules, is a poor substrate for P-glycoprotein, and inhibits the growth of paclitaxel-resistant tumors in xenograft models. Two radiolabeled photoaffinity analogues of HTI-286, designated 4-benzoyl-N,beta,beta-trimethyl-l-phenylalanyl-N(1)-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]-N(1),3-dimethyl-l-valinamide (probe 1) and N,beta,beta-trimethyl-l-phenylalanyl-4-benzoyl-N-[(1S,2E)-3-carboxy-1-isopropyl-2-butenyl]-N,beta,beta-trimethyl-l-phenylalaninamide (probe 2), were made to help identify HTI-286 binding sites in tubulin. HTI-286, probe 1, and probe 2 had similar affinities for purified tubulin [apparent K(D(app)) = 0.2-1.1 microM], inhibited polymerization of purified tubulin approximately 80%, and were potent inhibitors of cell growth (IC(50) = 1.0-22 nM). Both radiolabeled probes labeled exclusively alpha-tubulin. Labeling by [(3)H]probe 1 was inhibited by probe 1, HTI-286, vinblastine, or dolastatin 10 (another peptide antimitotic agent that depolymerizes microtubules) but was either unaffected or enhanced (at certain temperatures) by colchicine or paclitaxel. [(3)H]Probe 1 also labeled exclusively tubulin in cytosolic extracts of whole cells. The major, if not exclusive, contact site for probe 1 was mapped to residues 314-339 of alpha-tubulin and corresponds to the sheet 8 and helix 10 region. This region is known to (1) have longitudinal interactions with beta-tubulin across the interdimer interface, (2) have lateral interactions with adjacent protofilaments, and (3) contact the N-terminal region of stathmin, a protein that induces depolymerization of tubulin. Binding of probe 1 to this region may alter the conformation of tubulin outside the labeling domain, since enzymatic removal of the C-terminus of only alpha-tubulin by subtilisin after, but not before, photolabeling is blocked by probe 1. These results suggest that hemiasterlin is in close contact with alpha-tubulin and may span the interdimer interface so that it contacts the vinblastine- and dolastatin 10-binding sites believed to be in beta-tubulin. In addition, we speculate that antimitotic peptides mimic the interaction of stathmin with tubulin.
Analogs of bradykinin with restricted conformational freedom (1975)

Three analogs of bradykinin have been synthesized which bear an alpha-methyl group in the place of an alpha proton at position, 4, 5, or 8. Such analogs possess restricted conformational freedom and are of interest for three reasons. (1) They may provide information about the receptor-bound conformation of the peptide. (2) They may provide a route to antagonists of the native peptide. (3) They may be degraded slowly by proteolytic enzymes. None of the analogs described here antagonized the action of bradykinin, but one exhibited tissue specificity and decreased pulmonary inactivation in the rat.
Alternative Dispute Resolution in the Workplace: Concepts and Techniques for Human Resource Executives and Their Counsel (2000)

Alternative Dispute Resolution in the Workplace: Concepts and Techniques for Human Resource Executives and Their Counsel, by E. Patrick McDermott with Arthur Eliot Berkeley,1996, Westport, CT: Quorum Books. Reviewers: Penelope R. Mercurio-Jennings and William P Jennings, California State University, Northridge Alternative Dispute Resolution in the Workplace: Concepts and Techniques for Human Resource Executives and Their Counsel seeks to explain the uses, benefits, and costs of various nonjudicial alternatives to disputes arising in the workplace. Structurally, the book is divided into three chapters and an appendix. Chapter 1 (The Changing Legal and Legislative Landscape) discusses recent legislation and court decisions focusing on the legality of mandatory binding arbitration provisions. Chapter 2 (Varieties of Alternative Dispute Resolution) sets forth examples of alternative methods of resolving disputes between workers and employers from such simple and obvious concepts as an policy to more complicated arbitration/mediation models. Chapter 3 (The Trend: Corporate Alternative Dispute Resolution Programs) and the appendix provide examples of corporate dispute resolution plans and programs from companies like Northrop, Rockwell International, Travelers Group, and, in detail, Brown & Root. The book reviews workplace dispute resolution techniques available to employers, including binding arbitration, and, to a certain extent, such techniques as open-door policy, peer review, ombudsman, employer-run dispute resolution procedures, unionmanagement model, mediation, and fact-finding. The book analyzes these dispute resolution alternatives as management tools to help avoid or reduce the cost of litigation and to protect rights of employers to manage workers. The most useful part of the book is the discussion of available ADR methods, particularly the actual plan used by Brown & Root (in the appendix). Although the book may be useful to human resource managers or corporate lawyers who are considering the implementation of an ADR plan, the book cannot be viewed as a comprehensive analysis of the use of ADR in the workplace. First, although there is a good discussion of the benefits of ADR, the disadvantages are glossed over. The authors ignore the importance (especially for employers in the long run) of having actual court decisions interpreting recent employment statutes such as the Civil Rights Act of 1991. Second, the major focus of the book is on mandatory binding arbitration. Other forms of alternative dispute resolution are, in general, merely mentioned. Thus, the book probably would have been more effective if the discussion had been limited to issues related to binding arbitration and the title had been changed accordingly. The authors might have intended to discuss nonjudicial workplace dispute resolution in an objective manner, neither pro-worker nor pro-management. …
Hidden Lineage Complexity of Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies Uncovered by Digital Panning and Native-Like gp140 Trimer (2017)

Germline precursors and intermediates of broadly neutralizing antibodies (bNAbs) are essential to the understanding of humoral response to HIV-1 infection and B-cell lineage vaccine design. Using a native-like gp140 trimer probe, we examined antibody libraries constructed from donor-17, the source of glycan-dependent PGT121-class bNAbs recognizing the N332 supersite on the HIV-1 envelope glycoprotein. To facilitate this analysis, a digital panning method was devised that combines biopanning of phage-displayed antibody libraries, 900 bp long-read next-generation sequencing, and heavy/light (H/L)-paired antibodyomics. In addition to single-chain variable fragments resembling the wild-type bNAbs, digital panning identified variants of PGT124 (a member of the PGT121 class) with a unique insertion in the heavy chain complementarity-determining region 1, as well as intermediates of PGT124 exhibiting notable affinity for the native-like trimer and broad HIV-1 neutralization. In a competition assay, these bNAb intermediates could effectively compete with mouse sera induced by a scaffolded BG505 gp140.681 trimer for the N332 supersite. Our study thus reveals previously unrecognized lineage complexity of the PGT121-class bNAbs and provides an array of library-derived bNAb intermediates for evaluation of immunogens containing the N332 supersite. Digital panning may prove to be a valuable tool in future studies of bNAb diversity and lineage development.
Heterogeneous sources model for DSL access multiplexers (2008)

A digital subscriber line access multiplexer that multiplexes streaming packetised telephony and/or video-on-demand traffic is studied. To this end, the distribution of the amount of work in a discrete-time single-server queuing model with heterogeneous sources and general packet lengths is calculated. Obtaining actual data concerning the distribution of this quantity is notoriously hard. How the tail distribution can be extracted from the steady-state probability generating function through a multiple-pole series expansion is outlined.
Direct estimation of global longitudinal strain from echocardiograms using a logarithm-scaled Fourier magnitude correlation (2020)

We present a new method for measuring global longitudinal strain and global longitudinal strain rate from 2D echocardiograms using a logarithmic-transform correlation (LTC) method. In contrast to traditional echocardiography strain analysis, our approach does not require cardiac chamber segmentation and regularization. The algorithm was benchmarked against two conventional strain analysis methods using synthetic left ventricle ultrasound images. Measurement error was assessed as a function of contrast-to-noise ratio (CNR) using mean absolute error and root-mean-square error and showed better agreement to the ground truth for strain($R^2$ = 0.91) and strain rate($R^2$ = 0.85) as compared to conventional algorithms (strain($R^2$ = 0.7), strain rate($R^2$ = 0.7)). Also, our method was unaffected by CNR. A 200% increase in strain measurement accuracy was observed compared to the conventional algorithms. Subsequently, we tested the method using a 54-subject clinical cohort (20 subjects diseased with cardiomyopathy, 34 healthy controls). Our method distinguished between normal and abnormal left ventricular function with an AUC = 0.85, a 10% improvement over the conventional GLS algorithms.
Containing tensions: psychoanalysis and modern policymaking (2018)

What can contemporary psychoanalysis offer to modern policy making and progressive political practice?Psychoanalysis today offers a distinct vision for politics, bringing learning from the dyadic encounter between therapist and patient and from interventions across the strata of society.It posits that there is an urgent need for emotionally intelligent policy making, which grapples with and roots itself in the complex realities of social relations, and forges negotiated solutions.We have become used to rational-linear, 'top down' policy making, but such processes fail to contend with the messy and often conflictual systems and domains in which we live, where our fears, desires and agonies inevitably play a role.Modern psychoanalysis asks that policy thinking uses this understanding of society as a departure point for theory and action.
Total Synthesis of Asimicin and Bullatacin (2000)

The efficient total synthesis of asimicin, 1, and bullatacin, 2, has demonstrated the advantages of three different strategies for the synthesis of the tricyclic intermediates 6 and 7, which represent the key fragment of the bis-THF Annonaceous acetogenins. The naked carbon skeleton strategy is based on the production of all asymmetric centers by selective placement of the oxygen functions onto an unsaturated, nonfunctionalized carbon skeleton. Diversity in this approach arises from the relative timing of highly stereoselective reactions, such as the Sharpless asymmetric dihydroxylation (AD) reaction, the Kennedy oxidative cyclization (OC) with rhenium(VII) oxide, the Mitsunobu-type alcohol epimerization reaction, and the Williamson etherification reaction. The convergent strategy, which is based on the combinatorial coupling of two series of diastereomeric fragments, to produce intermediates such as 11 and 12, enjoys the advantages of both efficiency and versatility. The third approach, which is based on partially functionalized intermediates, such as 13, combines the advantages of both the linear and the convergent strategies-synthetic efficiency and diversity.
Expert Summaries (2005)

Provides an abstract for each of the exprt presentations and a brief professional biography of each presenter. The complete presentations were not made available for publication as part of the conference proceedings.
Winning Play in Spectrum Auctions (2009)

We describe factors that make bidding in large spectrum auctions complex — including exposure and budget problems, the role of timing within an ascending auction, and the possibilities for price forecasting — and how economic and game-theoretic analysis can assist bidders in overcoming these problems. We illustrate with the case of the FCC’s Advanced Wireless Service auction, in which a new entrant, SpectrumCo, faced all these problems yet managed to purchase nationwide coverage at a discount of roughly a third relative to the prices paid by its incumbent competitors in the same auction, saving more than a billion dollars.