gebhart/patrepeval huggingface dataset:
High Speed Page Matching (2009)

In a print production system, the ability to associate each page with its original electronic form enables a number of important automation services, such as alternate-source page insertion, page/sheet routing and aspects of JDF-compliance. This work demonstrates the efficacy of a method capable of matching a scanned version of an incoming page to an original RIP, and was tested with a library of a thousand sample commercial pages. Frequency domain analysis suggests that low-resolution representations of pages can be used for matching purposes. This notion is corroborated by experimental results; a 98% correct matching is achieved for pages reduced to a bit-depth of 1-bit at only 1 dpi using a simple XOR method, and a perfect matching rate was achieved using pages represented at 16 dpi at a variety of bit depths using a sum of squared errors measurement. The method is implemented without placing any extra ink on each page.
Lung Adenocarcinomas: A Novel KRAS/EGFR Exon 21 Double Mutation with Limited Response to TKI Treatment and Two Rare EGFR Exon 19 Deletions with Variable Response (2016)

Alexander JJ Smits1,2, Paul Roepman1, Niels JM Claessens 3, Franz M Schramel4 and J Alain Kummer 1*
Etude cinétique de l'attaque acide de la sépiolite: modifications des propriétés texturales (1986)

Resume Dans ce travail on a étudié l'influence des conditions expérimentales du traitement acide d'une sépiolite sur la vitesse d'extraction des ions Mg et la variation des propriétés texturales des produits résultants. On a élaboré un modèle cinétique pour l'attaque acide de la sépiolite ce qui nous a permis de calculer les paramètres cinétiques et, en dernier lieu d'obtenir des valeurs pour l'energie d'activation du processus.
On instant messaging worms, analysis and countermeasures (2005)

We provide a collection of minor results on the area of Instant Messaging (IM) worms, which has received relatively little attention in the formal literature. We review selected IM worms and summarize their main characteristics, motivating a brief overview of the network formed by IM contact lists, and a discussion of theoretical consequences of worms in such networks. Existing methods to restrict an IM worm epidemic are analyzed in terms of usability and effectiveness, leading to the suggestion of two minor variations to limit IM worm propagation. We believe these variations are more user-friendly and effective than existing published methods. We also provide brief results of a three and a half year user study of IM text messaging and file transfer frequency in a moderate-size public IM network -- the largest such study to date -- which is of independent interest, but also supports in part the preceding claim regarding user-friendliness.
Data from Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy (2023)

&lt;div&gt;Abstract&lt;p&gt;The inflammatory microenvironment of solid tumors creates a protumorigenic milieu that resembles chronic inflammation akin to a subverted wound healing response. Here, we investigated the effect of converting the tumor microenvironment from a chronically inflamed state to one of acute microbial inflammation by injecting microbial bioparticles directly into tumors. Intratumoral microbial bioparticle injection led to rapid and dramatic changes in the tumor immune composition, the most striking of which was a substantial increase in the presence of activated neutrophils. &lt;i&gt;In situ&lt;/i&gt; photoconversion and intravital microscopy indicated that tumor neutrophils transiently switched from sessile producers of VEGF to highly motile neutrophils that clustered to make neutrophil-rich domains in the tumor. The neutrophil clusters remodeled tumor tissue and repressed tumor growth. Single-cell transcriptional analysis of microbe-stimulated neutrophils showed a profound shift in gene expression towards heightened activation and antimicrobial effector function. Microbe-activated neutrophils also upregulated chemokines known to regulate neutrophil and CD8&lt;sup&gt;+&lt;/sup&gt; T-cell recruitment. Microbial therapy also boosted CD8&lt;sup&gt;+&lt;/sup&gt; T-cell function and enhanced the therapeutic benefit of checkpoint inhibitor therapy in tumor-bearing mice and provided protection in a model of tumor recurrence. These data indicate that one of the major effector mechanisms of microbial therapy is the conversion of tumor neutrophils from a wound healing to an acutely activated cytotoxic phenotype, highlighting a rationale for broader deployment of microbial therapy in the treatment of solid cancers.&lt;/p&gt;Significance:&lt;p&gt;Intratumoral injection of microbial bioparticles stimulates neutrophil antitumor functions, suggesting pathways for optimizing efficacy of microbial therapies and paving the way for their broader utilization in the clinic.&lt;/p&gt;&lt;/div&gt;
Quantitative Trait Locus Mapping for Drought Tolerance in Soybean Recombinant Inbred Line Population (2021)

Improving drought stress tolerance of soybean could be an effective way to minimize the yield reduction in the drought prevailing regions. Identification of drought tolerance-related quantitative trait loci (QTLs) is useful to facilitate the development of stress-tolerant varieties. This study aimed to identify the QTLs for drought tolerance in soybean using a recombinant inbred line (RIL) population developed from the cross between a drought-tolerant 'PI416937' and a susceptible 'Cheonsang' cultivar. Phenotyping was done with a weighted drought coefficient derived from the vegetative and reproductive traits. The genetic map was constructed using 2648 polymorphic SNP markers that distributed on 20 chromosomes with a mean genetic distance of 1.36 cM between markers. A total of 10 QTLs with 3.52-4.7 logarithm of odds value accounting for up to 12.9% phenotypic variance were identified on seven chromosomes. Five chromosomes-2, 7, 10, 14, and 20-contained one QTL each, and chromosomes 1 and 19 harbored two and three QTLs, respectively. The chromosomal locations of seven QTLs overlapped or located close to the related QTLs and/or potential candidate genes reported earlier. The QTLs and closely linked markers could be utilized in maker-assisted selection to accelerate the breeding for drought tolerance in soybean.
Preparation of micro-biosensor for continuous glucose monitoring (2015)

Amperometric glucose sensors with a diameter of less than 10 μm were fabricated by the immobilization of glucose oxidase ( GOx ) on carbon fiber electrodes. Carbon fiber electrodes with platinum thin film were also prepared using electroplating and sputtering. The combination of electrodeposition and electropolymerization was employed for the immobilization of GOx . Although the introduction of Pt film satisfactorily improved the oxidation current of the electrode to hydrogen peroxide, sensitivities of obtained GOx -immobilized electrodes to glucose were not significant. Formation of electroplated-platinum thin film on carbon fiber was effective to reduce the influence of electroactive compounds existing in biological fluid such as ascorbic and uric acids.
ChemInform Abstract: Electrophilic Fluorination at Saturated Sites. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Accurate Dictionary Learning with Direct Sparsity Control (2018)

Dictionary learning is a popular method for obtaining sparse linear representations for high dimensional data, with many applications in image classification, signal processing and machine learning. In this paper, we introduce a novel dictionary learning method based on a recent variable selection algorithm called Feature Selection with Annealing (FSA). Because FSA uses an L0 constraint instead of the L1 penalty, it does not introduce any bias in the coefficients and obtains a more accurate sparse representation. Furthermore, the L0 constraint makes it easy to directly specify the desired sparsity level instead of indirectly through a L1 penalty. Finally, experimental validation on real gray-scale images shows that the proposed method obtains higher accuracy and efficiency in dictionary learning compared to classical methods based on the L1 penalty.
Reactions of Primary Organosilanes on Transition Metal Surfaces. Identification of the First Surface-Bound Silylynes (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of Primary Organosilanes on Transition Metal Surfaces. Identification of the First Surface-Bound SilylynesMichael J. Hostetler, Ralph G. Nuzzo, and Gregory S. GirolamiCite this: J. Am. Chem. Soc. 1994, 116, 25, 11608–11609Publication Date (Print):December 1, 1994Publication History Published online1 May 2002Published inissue 1 December 1994https://pubs.acs.org/doi/10.1021/ja00104a067https://doi.org/10.1021/ja00104a067research-articleACS PublicationsRequest reuse permissionsArticle Views113Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
A Study on Storytelling for Regional Product Perception - Focusing on ChunCheon Nephrite - (2020)

춘천 동면 월곡리는 세계 유일 연옥(백옥) 광산이 있으며 대일 광업에서는 춘천 연옥을 활용한 제품 개발 및 판매, 다양한 서비스 제공하고 있다. 춘천 특산물인 연옥의 인지도 및 가치 상승을 위해 지역 캐릭터 중 우수사례인 울산광역시 ‘울산큰애기’ ․ 고양시 ‘고양고양이’ ․ 공주시 ‘고마곰과 공주’의 스토리텔링 및 활용 전략 중심으로 사례조사 및 분석하였다. 분석 결과 세 사례의 스토리텔링은 지역 속 여러 특성을 연계하여 타 지역과 변별성 및 지역성을 두었으며 의인화를 통해 SNS와 지역 홍보를 위한 오프라인 활동을 지역민과 관광객에게 지속적으로 노출하여 친근감 및 인지도를 형성 하였다. 이를 춘천 연옥의 인지도 구축을 위해 적용하였다. 춘천 연옥과 춘천시의 특성인 호반의 도시를 조사한 결과 두 소재는 ‘물’과 연계됨을 알 수 있었다. 향후 춘천시 호반의 도시 이미지와 연계하여 춘천 특산물 춘천 연옥을 스토리를 활용하여 온라인과 오프라인 활동을 지역민과 관광객에게 지속적으로 노출할 경우 타 지역과 변별성을 가질 수 있으며 춘천시 호반의 도시로서의 가치뿐만 아니라 춘천 특산물인 연옥의 가치와 인지도 또한 상승할 것이다.
Dual-Responsive Microgels for Structural Repair and Recovery of Nonwoven Membranes for Liquid Filtration (2021)

This study presents dual-responsive colloidal microgels to repair nonwoven fiber mats (NWFs) and recover their native morphological and functional properties. The formulation comprises poly(N-isopropylacrylamide-co-acrylic acid) (PNIPAm-co-AA) microgels loaded with iron oxide nanoparticles acting as magneto-responsive “bricks” and poly(N-isopropylacrylamide-co-N-4-benzoylphenyl acrylamide) (PNIPAm-co-BPAm) serving as photo-cross-linkable “mortar”. The formulation is employed to repair small tears in meltblown polypropylene (PP) and polybutylene terephthalate (PBT) NWFs and recover the functional properties of the native membranes. Specifically, magnetically directed and UV-light-triggered repair recovers (i) the topological integrity, as shown by optical microscopy and image analysis of PP and PBT NWFs, (ii) the mechanical properties, as demonstrated by the values of tensile modulus of native, damaged, and repaired PP NWFs, and (iii) the permeability to sodium chloride of both PP and PBT NWFs. A comparative study of repair using magneto-responsive and photo-cross-linkable vs photo-cross-linkable-only formulations demonstrate that magnetic localization is vital to ensure rapid, spatially accurate, and effective recovery of the morphological and functional properties of damaged NWFs.
Shp-2 modulates aspects of T cell exhaustion differently from PD-1 (2017)

International audience
Color halftoning based on Neugebauer Primary Area Coverage (2017)

In this paper, we propose a halftoning method with Neugebauer Primary Area Coverage (NPAC) direct binary search (DBS), with the optimized human visual system (HVS) model, we are able obtain homogeneous and smooth hafltone colored image. The halftoning is based on separating the colored image represented in Neugebauer Primary in three channels based on human visual system, with swap-only DBS, we arrange the dots to bring the error metric to its minimum and the optimized halftone image is obtained. The separation of chrominance HVS filters between red-green and blue-yellow channels allows us to represent HVS more accurately. Color halftone images generated using this method and method of using combined chrominance filter is compared.
Reliability and degradation of small molecule-based organic light-emitting devices (OLEDs) (2002)

Studies of degradation mechanisms in small molecule-based organic light-emitting devices (OLEDs) are reviewed. A special emphasis is given to OLEDs based on tris (8-hydroxyquinoline) aluminum (AlQ/sub 3/), an emitter and electron transport material used in the majority of OLEDs emitting from the green to the red part of the spectrum. Different strategies used for increasing device stability are addressed and the models proposed to explain experimental observations related to OLED operational stability are discussed. Although none of the presently proposed models can explain all experimental observations, the largest body of experimental evidence appears to be consistent with a model based on the instability of cationic AlQ/sub 3/ species, produced by the injection of holes into the AlQ/sub 3/ electron transport and emitter layer. Other models may be of importance in explaining degradation behavior on different time scales. Models based on redistribution of space charge appear to be responsible for reversible short-term degradation, while a model based on indium migration may be important for degradation on very long time scales.
Split Compilation for Security of Quantum Circuits (2021)

An efficient quantum circuit (program) compiler aims to minimize the gate-count - through efficient instruction translation, routing, gate, and cancellation - to improve run-time and noise. Therefore, a high-efficiency compiler is paramount to enable the game-changing promises of quantum computers. To date, the quantum computing hardware providers are offering a software stack supporting their hardware. However, several third-party software toolchains, including compilers, are emerging. They support hardware from different vendors and potentially offer better efficiency. As the quantum computing ecosystem becomes more popular and practical, it is only prudent to assume that more companies will start offering software-as-a-service for quantum computers, including high-performance compilers. With the emergence of third-party compilers, the security and privacy issues of quantum intellectual properties (IPs) will follow. A quantum circuit can include sensitive information such as critical financial analysis and proprietary algorithms. Therefore, submitting quantum circuits to untrusted compilers creates opportunities for adversaries to steal IPs. In this paper, we present a split compilation methodology to secure IPs from untrusted compilers while taking advantage of their optimizations. In this methodology, a quantum circuit is split into multiple parts that are sent to a single compiler at different times or to multiple compilers. In this way, the adversary has access to partial information. With analysis of over 152 circuits on three IBM hardware architectures, we demonstrate the split compilation methodology can completely secure IPs (when multiple compilers are used) or can introduce factorial time reconstruction complexity while incurring a modest overhead (~ 3% to ~ 6% on average).
Three-dimensional electromagnetic power deposition in tumors using interstitial antenna arrays (1989)

Interstitial arrays of insulated antennas have shown promise for microwave hyperthermia treatment of deep-seated tumors. Available analytical techniques for predicting the electromagnetic (EM) power deposition of these antennas have been limited to the case of a homogeneous conductive medium surrounding the array. Since tumors and host tissue may differ in their electrical characteristics, it is necessary to consider the impact of this variation in electrical properties and the geometry of the tumor in the calculation of the EM field distribution and power deposition pattern when modeling interstitial antennas. In this paper a three-dimensional model of a tumor of arbitrary shape subjected to the fields of an interstitial antenna array is developed to predict the EM power deposition in an inhomogeneous tumor-tissue medium. The volume integral equation for the imbedded tumor is developed and solved by method of moments. The incident fields are calculated based on the available formulation of interstitial antennas in homogeneous media. The accuracy of the developed computer code was checked by comparing the results from the volume integral approach with the Mie solution for the special case of spherical tumors. Good comparison was obtained for tumors with properties approximately 25 percent different from those of the surrounding tissue. Comparisons of results from models of antenna arrays with and without imbedded tumors show significant differences in their predictions of the EM power deposition in the tumor. Hyperthermia protocols generally specify uniform temperature distribution within the tumor. The developed inhomogeneous model was used to examine the feasibility of controlling the uniformity of the power deposition pattern in large tumors by adjusting the amplitude or relative phase between the array elements. Results are presented to show that a phase lead of +90 degrees or relative amplitude of 4.0 on one antenna in a square array of four antennas could be used to shift the power deposition pattern to sequentially heat outer portions of a 2 cm diameter tumor, thereby achieving a more uniform time-averaged temperature distribution in the tumor.
Molecular Cloning, Biochemical Characterization, and Partial Protective Immunity of the Heme-Binding GlutathioneS-Transferases from the Human HookwormNecator americanus (2010)

Hookworm glutathione S-transferases (GSTs) are critical for parasite blood feeding and survival and represent potential targets for vaccination. Three cDNAs, each encoding a full-length GST protein from the human hookworm Necator americanus (and designated Na-GST-1, Na-GST-2, and Na-GST-3, respectively) were isolated from cDNA based on their sequence similarity to Ac-GST-1, a GST from the dog hookworm Ancylostoma caninum. The open reading frames of the three N. americanus GSTs each contain 206 amino acids with 51% to 69% sequence identity between each other and Ac-GST-1. Sequence alignment with GSTs from other organisms shows that the three Na-GSTs belong to a nematode-specific nu-class GST family. All three Na-GSTs, when expressed in Pichia pastoris, exhibited low lipid peroxidase and glutathione-conjugating enzymatic activities but high heme-binding capacities, and they may be involved in the detoxification and/or transport of heme. In two separate vaccine trials, recombinant Na-GST-1 formulated with Alhydrogel elicited 32 and 39% reductions in adult hookworm burdens (P < 0.05) following N. americanus larval challenge relative to the results for a group immunized with Alhydrogel alone. In contrast, no protection was observed in vaccine trials with Na-GST-2 or Na-GST-3. On the basis of these and other preclinical data, Na-GST-1 is under possible consideration for further vaccine development.
CORRELACIÓN ENTRE WORLD REFERENCE BASE Y SOIL TAXONOMY PARA LOS SUELOS DE LA VII REGIÓN DEL MAULE DE CHILE (2007)

Se realizo una correlacion entre World Referente Base (WRB) y Soil Taxonomy (ST), para los suelos de la VII Region del Maule de Chile. Once Grupos de Suelos de Referencia definidos por WRB fueron identificados: Lixisols (499.965 ha), Durisols (62.539 ha). Umbrisols (62.387 ha), Phaeozems (52.823 ha), Cambisols (46.982 ha), Andosols (45.645 ha), Regosols (13.701 ha), Fluvisols (6.908 ha), Luvisols (6.132 ha), Planosols (4.606 ha) y Vertisols (640 ha). Estos suelos fueron localizados principalmente en la Depresion Intermedia (Graben Central) de Chile. Los Andosols se describieron hacia la Cordillera de los Andes y los Luxisols principalmente hacia la Cordillera de la Costa. Las correlaciones mas estrechas se observaron entre Lixisols y Alfisols, Umbrisols, Cambisols e Inceptisols, Phaeozems y Mollisols, y finalmente entre Andosols y Andisols. Los Durisols y los restantes Grupos de Suelos de Referencia no mostraron una correlacion definida hacia algun Orden de Suelos
Kinetic Studies of the Binding of Acridinecarboxamide Topoisomerase Poisons to DNA:  Implications for Mode of Binding of Ligands with Uncharged Chromophores (2002)

We have used stopped-flow spectrophotometry and the sodium dodecyl sulfate sequestration technique to study the kinetics of dissociation of DNA complexes of the mixed topoisomerase I/II poison N-[2-(dimethylamino)ethyl]acridine-4-carboxamide (termed DACA) and a range of related linear tricyclic carboxamides with neutral chromophores. Complexes of DACA and related acridine and phenazinecarboxamides bearing an N,N-dimethylaminoethyl side chain dissociate from calf thymus DNA by a kinetic pathway involving four discernible steps in a manner similar to complexes of N-[(2-dimethylamino)ethyl]-9-aminoacridine-4-carboxamide (termed 9-amino-DACA). We infer from these findings that the side chains of DACA, its phenazine homologue, and 9-amino-DACA make comparable interactions with the DNA base pairs. In the case of 9-amino-DACA, a selective topoisomerase II poison, these are known, by crystallographic analysis, to involve hydrogen-bonding interactions between the protonated dimethylammonium group of the side chain and the O6/N7 atoms of guanine and to include a bridging water molecule hydrogen bonded to the carboxamide group and a phosphate oxygen. By contrast, we find that other linear tricyclic carboxamides with neutral chromophores which lack a peri nitrogen atom and are biologically inactive dissociate from DNA by a different mechanism in which it appears their side chains fail to interact with guanine. We conclude that the ability of the carboxamide group to lie preferentially in the plane of the chromophore, so facilitating the dimethylammonium-guanine hydrogen bond and ensuring maintenance of the water-bridged carboxamide-phosphate interaction, is a critical requirement for antitumor activity among ligands of the linear tricyclic carboxamide class. However, unlike the situation for 9-amino-DACA, for ligands with uncharged chromophores containing peri nitrogen atoms such as DACA, this outcome is possible with the 4-carboxamide group rotated cis or trans with respect to the ring nitrogen. This difference may have relevance to the ability of DACA to be a dual poison of both topoisomerases I and II.