gebhart/patrepeval huggingface dataset:
A study of a multi-pole magnetic generator for low-frequency vibrational energy harvesting (2009)

This paper theoretically and experimentally investigates voltage enhancement effects using a multi-pole magnet array in a magnetic energy harvester. The use of multiple magnetic poles is shown to increase the frequency and amplitude of the output voltage, addressing one of the primary disadvantages of magnetic transduction schemes, especially for low-frequency vibrations. Experimental results from a four-pole prototype demonstrate a three times improvement in rms voltage as compared to conventional single-magnet designs along with frequency up-conversion where the frequency content of the electrical output occurs at harmonics of the mechanical excitation frequency. The magnetic multi-pole approach is also further studied through simulation-based parametric analysis.
On Track for Efficiency: Concurrent Multiband Envelope-Tracking Power Amplifiers (2016)

The number of wireless devices worldwide has increased exponentially over the past decade, inherently imposing consumer requirements for faster data rates and longer device life. Current wireless standards such as long-term evolution (LTE), worldwide interoperability for microwave access (WiMAX), and the family of IEEE 802.11a/g/n/ac/ad for home-networking use orthogonal frequency-division multiplexing (OFDM) as their basis for digital multicarrier modulation. An option for increasing OFDM data output is through the expansion of the constellation symbols or the number of data subcarriers
Adapting a Wacker-type catalyst system to the palladium-catalyzed oxidative carbonylation of aliphatic polyols (2011)

Polyols, which can be obtained readily from bio-feedstock, are converted efficiently into their corresponding cyclic carbonates by using a Wacker-type Pd/Mn catalyst system. A fine tuned redox cascade is essential in ensuring a high productivity of the Pd catalyst in the oxidative carbonylation reaction. Turnover numbers up to 784 molproduct/molpalladium were achieved.
α lipoic acid inhibits human T‐cell migration: Implications for multiple sclerosis (2004)

We have demonstrated previously the ability of the antioxidant alpha lipoic acid (ALA) to suppress and treat a model of multiple sclerosis (MS), relapsing experimental autoimmune encephalomyelitis (EAE). We describe the effects of ALA and its reduced form, dihydrolipoic acid (DHLA), on the transmigration of human Jurkat T cells across a fibronectin barrier in a transwell system. ALA and DHLA inhibited migration of Jurkat cells in a dose-dependent fashion by 16-75%. ALA and DHLA reduced matrix metalloproteinase-9 (MMP-9) activity by 18-90% in Jurkat cell supernatants. GM6001, a synthetic inhibitor of MMP, reduced Jurkat cell migration, but not as effectively as ALA and DHLA did. Both ALA and DHLA downmodulated the surface expression of the alpha4beta1 integrin (very late activation-4 antigen; VLA-4), which binds fibronectin and its endothelial cell ligand vascular cell adhesion molecule-1 (VCAM-1). Moreover, ALA, but not DHLA, reduced MMP-9-specific mRNA and extracellular MMP-9 from Jurkat cells and their culture supernatants as detected by relative reverse transcriptase-polymerase chain reaction (RT-PCR) and enzyme-linked immunosorbent assay (ELISA), respectively. ALA and DHLA inhibited Jurkat cell migration and have different mechanisms for inhibiting MMP-9 activity. These data, coupled with its ability to treat relapsing EAE, suggest that ALA warrants investigation as a therapy for MS.
Photocatalytic Carbon Dioxide Reduction with Rhodium‐based Catalysts in Solution and Heterogenized within Metal–Organic Frameworks (2015)

The first photosensitization of a rhodium-based catalytic system for CO2 reduction is reported, with formate as the sole carbon-containing product. Formate has wide industrial applications and is seen as valuable within fuel cell technologies as well as an interesting H2 -storage compound. Heterogenization of molecular rhodium catalysts is accomplished via the synthesis, post-synthetic linker exchange, and characterization of a new metal-organic framework (MOF) Cp*Rh@UiO-67. While the catalytic activities of the homogeneous and heterogeneous systems are found to be comparable, the MOF-based system is more stable and selective. Furthermore it can be recycled without loss of activity. For formate production, an optimal catalyst loading of ∼10 % molar Rh incorporation is determined. Increased incorporation of rhodium catalyst favors thermal decomposition of formate into H2 . There is no precedent for a MOF catalyzing the latter reaction so far.
On-line peptide sequencing by enzymic hydrolysis, high performance liquid chromatography, and thermospray mass spectrometry (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOn-line peptide sequencing by enzymic hydrolysis, high performance liquid chromatography, and thermospray mass spectrometryH. Y. Kim, D. Pilosof, D. F. Dyckes, and M. L. VestalCite this: J. Am. Chem. Soc. 1984, 106, 24, 7304–7309Publication Date (Print):November 1, 1984Publication History Published online1 May 2002Published inissue 1 November 1984https://pubs.acs.org/doi/10.1021/ja00336a002https://doi.org/10.1021/ja00336a002research-articleACS PublicationsRequest reuse permissionsArticle Views106Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
HyperASPO: Fusion of Model and Hyper Parameter Optimization for Multi-objective Machine Learning (2021)

Current state of the art methods for generating Pareto-optimal solutions for multi-objective optimization problems mostly rely on optimizing the hyper-parameters of the models (HPO - hyper-parameter Optimization). Few recent, less studied methods focus on optimizing over the space of model parameters, leveraging the problem specific knowledge. We present a generic first-of-a-kind method, referred to as HyperASPO, that combines optimization over the spaces of both hyper-parameters and model parameters for multi-objective optimization of learning problems. HyperASPO consists of two stages. First, we perform a coarse HPO to determine a set of favorable hyper-parameter configurations. In the second step, for each of these configurations, we solve a sequence of weighted single objective optimization problems for estimating Pareto-optimal solutions. We generate the weights in the second step using an adaptive mesh constructed iteratively based on the metrics of interest, resulting in further refinement of Pareto frontier efficiently. We consider the widely used XGBoost (Gradient Boosted Trees) model and validate our method on multiple classification datasets. Our proposed method shows up to 20% improvement over the hypervolumes of Pareto fronts obtained through state of the art HPO based methods with up to 2× reduction in computational time.
Optimizing Pilots and Analog Processing for Channel Estimation in Cell-Free Massive MIMO with One-Bit ADCs (2018)

In a cell-free cloud radio access network (C-RAN) architecture, uplink channel estimation is carried out by a centralized baseband processing unit (BBU) connected to distributed remote radio heads (RRHs). When the RRHs have multiple antennas and limited radio front-end resources, the design of uplink channel estimation is faced with the challenges posed by reduced radio frequency (RF) chains and one-bit analog-to-digital converters (ADCs) at the RRHs. This work tackles the problem of jointly optimizing the pilot sequences and the pre-RF chains analog combiners with the goal of minimizing the sum of mean squared errors (MSEs) of the estimated channel vectors at the BBU. The problem formulation models the impact of the ADC operation by leveraging Bussgang's theorem. An efficient solution is developed by means of an iterative alternating optimization algorithm. Numerical results validate the advantages of the proposed joint design compared to baseline schemes that randomly choose either pilots or analog combiners.
Wired and Wireless Links to Bridge Networks: Seamlessly Connecting Radio and Optical Technologies for 5G Networks (2018)

As fifth-generation (5G) technology is expected to offer super-broadband mobile services with new features such as low latency for critical applications and low-power operation for Internet of Things (IoT) applications, it will use wireless interfaces for small or spot cells with a new RF resource, the high band (frequencies above 6 GHz), in addition to the low band (below 6 GHz) on macro and small cells coexisting with conventional mobile technologies [1]-[4]. Another feature of 5G wireless interfaces is more precise control of radio waves in space division through the use of multi-antenna technologies, such as massive multiple-input/multiple-output (MIMO) or beamforming [5].
Power through Purpose: The Realism of Idealism as a Basis for Foreign Policy. By Thomas I. Cook and Malcolm Moos. Baltimore, Md.: The Johns Hopkins Press [Toronto: Burns & MacEachern]. 1954. Pp. xii, 216. $5.00 approx. (1957)

Power through Purpose: The Realism of Idealism as a Basis for Foreign Policy. By Thomas I. Cook and Malcolm Moos. Baltimore, Md.: The Johns Hopkins Press [Toronto: Burns &amp; MacEachern]. 1954. Pp. xii, 216. $5.00 approx. - Volume 23 Issue 1
Bmp7 Maintains Undifferentiated Kidney Progenitor Population and Determines Nephron Numbers at Birth (2013)

The number of nephrons, the functional units of the kidney, varies among individuals. A low nephron number at birth is associated with a risk of hypertension and the progression of renal insufficiency. The molecular mechanisms determining nephron number during embryogenesis have not yet been clarified. Germline knockout of bone morphogenetic protein 7 (Bmp7) results in massive apoptosis of the kidney progenitor cells and defects in early stages of nephrogenesis. This phenotype has precluded analysis of Bmp7 function in the later stage of nephrogenesis. In this study, utilization of conditional null allele of Bmp7 in combination with systemic inducible Cre deleter mice enabled us to analyze Bmp7 function at desired time points during kidney development, and to discover the novel function of Bmp7 to inhibit the precocious differentiation of the progenitor cells to nephron. Systemic knockout of Bmp7 in vivo after the initiation of kidney development results in the precocious differentiation of the kidney progenitor cells to nephron, in addition to the prominent apoptosis of progenitor cells. We also confirmed that in vitro knockout of Bmp7 in kidney explant culture results in the accelerated differentiation of progenitor population. Finally we utilized colony-forming assays and demonstrated that Bmp7 inhibits epithelialization and differentiation of the kidney progenitor cells. These results indicate that the function of Bmp7 to inhibit the precocious differentiation of the progenitor cells together with its anti-apoptotic effect on progenitor cells coordinately maintains renal progenitor pool in undifferentiated status, and determines the nephron number at birth.
Effect of substituent groups of phenol-derivative dissolution inhibitors on inhibition efficiency (1996)

This paper focuses on the inhibition efficiency of t-Boc derivatives of bis-phenols. Several t- Boc derivatives of bis-phenols were synthesized and their inhibition effects were evaluated in novolac resin and poly (4-hydroxystyrene) (PHS). When the novolac resin was used as the matrix polymer, the inhibition effects were thought to be governed by both the hydrophobicity and molecular size of the inhibitors. On the other hand, in the case of PHS, the hydrophobicity of the inhibitor molecule was thought to be the dominant factor responsible for decreasing dissolution rates. In addition, the effects of the basic components of the developers were also investigated. Solutions of sodium hydroxide, tetramethylammonium hydroxide and tetraethylammonium hydroxide were employed as developers. The effects of the basic components on the dissolution rates of the resists varied with the matrix polymer of the resist. The dissolution rate of novolac resin was higher in NaOH solution than in the developers consisting of organic bases. However, the dissolution rates of novolac resin samples containing dissolution inhibitors were lower in NaOH solution than in developers consisting of organic bases. This phenomenon may be attributable to the hydrophilic properties of the cation of a developer.
Kinetics of Phenol Biodegradation by Heavy Metal Tolerant Rhizobacteria Glutamicibacter nicotianae MSSRFPD35 From Distillery Effluent Contaminated Soils (2020)

Biodegradation of phenol using bacteria is recognized as an efficient, environmentally friendly and cost-effective approach for reducing phenol pollutants compared to the current conventional physicochemical processes adopted. A potential phenol degrading bacterial strain <i>Glutamicibacter nicotianae</i> MSSRFPD35 was isolated and identified from <i>Canna indica</i> rhizosphere grown in distillery effluent contaminated sites. It showed high phenol degrading efficiency up to 1117 mg L<sup>-1</sup> within 60 h by the secretion of catechol 1,2-dioxygenase via ortho intradial pathway. The strain MSSRFPD35 possess both the catechol 1,2 dioxygenase and catechol 2,3 dioxygenase coding genes that drive the <i>ortho</i> and <i>meta</i> pathways, but the enzymatic assay revealed that the strain cleaves catechol via <i>ortho</i> pathway. Haldane's kinetic method was well fit to exponential growth data and the following kinetic parameter was obtained: μ<sup>∗</sup> = 0.574 h<sup>-1</sup>, <i>K</i> <sub>i</sub> = 268.1, <i>K</i> <sub>s</sub> = 20.29 mg L<sup>-1</sup>. The true μ<sub>max</sub> and <i>S</i> <sub>m</sub> were calculated as 0.37 h<sup>-1</sup> and 73.76 mg L<sup>-1</sup>, respectively. The Haldane's constant values were similar to earlier studies and healthy fitness depicted in correlation coefficient value <i>R</i> <sup>2</sup> of 0.98. Phenol degrading kinetic's was predicted using Haldane's model as <i>q</i> <sub>max</sub> 0.983, <i>K</i> <sub>i</sub>' 517.5 and <i>K</i> <sub>s</sub>' 9.152. Further, MSSRFPD35 was capable of utilizing different monocyclic and polycyclic aromatic hydrocarbons and to degrade phenol in the presence of different heavy metals. This study for the first time reports high phenol degrading efficiency of <i>G. nicotianae</i> MSSRFPD35 in the presence of toxic heavy metals. Thus, the strain <i>G. nicotianae</i> MSSRFPD35 can be exploited for the bioremediation of phenol and its derivatives polluted environments, co-contaminated with heavy metals.
Tunability of Pore Diameter and Particle Size of Amorphous Microporous Silica for Diffusive Controlled Release of Drug Compounds (2007)

Amorphous microporous silica (AMS) materials with variation in microporosity were prepared using an acid-catalyzed sol−gel procedure departing from tetraethylorthosilicate. The silicas were fined to specific particle sizes by crushing and sieving. AMS materials were loaded with 10 wt % ibuprofen either by uptake of molten ibuprofen or by adsorption of ibuprofen from a methylene chloride solution. DSC analysis of ibuprofen-loaded AMS confirmed the molecular dispersion of ibuprofen on the silica material. In vitro ibuprofen release from AMS carrier was investigated in simulated intestinal fluid and in a dissolution medium simulating the gastrointestinal tract with simulated gastric fluid followed by simulated intestinal fluid. The release of ibuprofen molecules from the AMS silica carrier is governed by diffusion. The diffusivity of ibuprofen in the investigated series of AMS samples was in the range 10-14−10-11 m2 s-1. By adapting the porosity and particle size of AMS, the release could be evenly spread over periods from 3 to 100 h. This flexibility of AMS opens perspectives for designing tailor-made controlled release formulations.
<title>Infrared focal plane array modeling</title> (1990)

A model for staring focal plane arrays is described. The model characterizes two types of detectors, the platinum silicide (PtSi) Schottky-barrier diode and the mercury-cadmiun-tellurium (MCT) detector. The MCT devices provide high performance in both the 3-5-micron and 8-12-micron regions, while the Schottky devices, functioning only in the 3-5-micron band, provide high density and economy.
Random Forest (2018)

In Chapter 4, we looked at the process of building a decision tree. Decision trees can overfit on top of the data in some cases—for example, when there are outliers in the data. Having correlated independent variables may also result in the incorrect variable being selected for splitting the root node.
Universal Thermoelectric Characteristic in Phase Change Memories (2015)

Thermoelectric effects play an important role in phase change memory (PCM), where phase transition and atomic migration are accelerated by temperature. A deep understanding of thermoelectric effects may allow a physics-based design of the cell structure and materials to optimize programming speed/energy and reliability. In this work we study the polarity-dependence of PCM characteristics, including crystallization, melting, electrical switching/holding, and ion migration. These characteristics show slower kinetics at negative voltage, which we attribute to thermoelectric effects of electrically-induced heating. We demonstrate a universal correlation of positive/negative kinetics, which we reproduce by modelling Thomson and Peltier heating in the PCM device.
Adaptive control in the presence of quantization and saturation: Application to laser beam steering by a liquid crystal device (2009)

This paper presents an investigation of adaptive control for a system with control quantization and magnitude and rate saturations. The application is laser beam steering by a liquid crystal device. The effects of using a linear time-invariant feedback loop along with the adaptive controller are discussed, as well as the effects of using nonlinear and linear plant models in the adaptive controller. In contrast to conventional fast steering mirrors, the liquid crystal device optically redirects the laser beam and has no moving parts or structural resonance, which often requires a stabilizing feedback controller prior to the adaptive controller. Simulation and experimental results demonstrate the effects on the adaptive control performance of choices of linear or nonlinear, and open or closed-loop plant models, and show which choices yield best performance.
Total Synthesis of Eleuthoside A; Application of Rh-Catalyzed Intramolecular Cyclization of Diazonaphthoquinone (2017)

The first total synthesis of (±)-eleutherol and eleuthoside A, the natural cytotoxic substances extracted from medicinal Indonesian plant, is described. First, the synthesis of (±)-eleutherol has been ­accomplished in nine steps starting from bromo methoxy aldehyde with the aid of diazo-transfer chemistry approach. Second, a metal-­catalyzed intramolecular cyclization reaction of the corresponding ­diazonaphthoquinone led to the desired eleuotherol, which served as a precursor to eleuthoside A. Then, several glycosidation routes, using different glucosyl donors, were experimented to reach effective O-glycosidation of eleutherol. The only successful strategy involved Koenigs–Knorr glycosidation using peracetyl glycosyl bromide in the presence of Ag2O and quinoline. This strategy furnished our desired acetylated glycoside of β-configuration, regioselectively. Finally, deacetylation and successive separation of diastereomers were conducted to give eleuthoside A.
Three-step photoionization of mercury for application to separation of mercury isomers (1982)

Development of techniques for separating isomeric nuclides is important to the investigation of schemes for gamma-ray lasers. In preparation for an experiment to separate 10/sup 14/ atoms of the /sub 197m/Hg (299 keV, tau/sub 1/2/ = 24 hours) isomer, we report isotopically selective resonance ionization of mercury atoms. This has been accomplished by three-step excitation via the 6/sup 3/P/sub 1/ and 8/sup 1/S/sub 0/ excited states, using three collinear pulsed laser beams of 254, 286, and 532 nm wavelengths from a Nd:YAG and two dye lasers. These beams were passed through a closed mercury-vapor cell containing electrostatic plates to which the ions were drawn. Ion current and fluorescent radiation were measured as a function of laser frequency. Hyperfine structures for the 254- and 286-nm transitions were observed.
Antimalarial sulfide, sulfone, and sulfonamide trioxanes (2000)

A series of trioxanes featuring sulfide, sulfone, and sulfonamide substituents in diverse positions has been prepared. Structure-activity relationship (SAR) generalizations highlight two major factors controlling the antimalarial potency of these new chemical entities: (1) the proximity of the sulfur-containing substituent to the crucial peroxide bond and (2) the oxidation state of the sulfur-containing substituent. Generally, sulfones are more antimalarially potent than the corresponding sulfides.
Encapsulation of RNA Molecules in BSA Microspheres and Internalization into Trypanosoma Brucei Parasites and Human U2OS Cancer Cells (2011)

Abstract RNA was encapsulated in bovine serum albumin (BSA) microspheres using a one‐step sonochemical process from an water–oil solvent biphasic system. Confocal microcoscopy and fluorescence‐activated cell sorting indicate that a CY3‐RNA (RNA labeled with red fluorescent indocarbocyanine Cy3 dye) sphere is encapsulated in the BSA outer sphere. The diameter of the sphere depends on the number of nucleotides of the RNA, ranging from 0.63 to 2.74 μm. Total RNA (t‐RNA) was used as a prototype for the future small interfering RNA (siRNA) delivery. A very broad size distribution characterizes the RNA spheres and therefore, among the loaded BSA spheres, there were sufficiently small spheres to be successfully introduced into trypanosoma brucei parasites and human osteosarcoma U2OS cancer cells.
Axial Mode Spectra of Planar Stripe Geometry Laser Diodes (1982)

The influence of spontaneous emission on the axial mode spectrum of semiconductor laser diodes is described by solving the wave equation of each mode and calculating the rate of spontaneous emission coupled into the mode. Since we employ a quantum mechanical gain model, spectral gain and spontaneous emission are unambiguously correlated to carrier density. Spectra of axial modes are calculated for different power levels, gain widths and cavity lengths.
Oral health assessment practices and perceptions of North American paediatric cardiologists (2017)

Assessments of oral health status were often deferred until immediately prior to cardiac surgery despite the cardiologist's perception that children with cardiac defects were at increased risk of oral disease and prior experience of surgical cancellation due to oral disease. Paediatricians may need to facilitate early oral assessment for these children.