gebhart/patrepeval huggingface dataset:
Angular momentum-dependent topological transport and its experimental realization using a transmission line network (2018)

Novel classical wave phenomenon analogs of the quantum spin Hall effect are mostly based on the construction of pseudo-spins. Here we show that the non-trivial topology of a system can also be realized using orbital angular momentum through angular-momentum-orbital coupling. The idea is illustrated with a tight-binding model and experimentally demonstrated with a transmission line network. We show experimentally that even a very small network cluster exhibits one-way topological edge states, and their properties can be described in terms of local Chern numbers. Our work provides a new mechanism to realize counterparts of the quantum spin Hall effect in classical waves and may offer insights for other systems.
Multiple sources of calcium for contraction of the human urinary bladder muscle (1989)

1. KCl, carbachol, neurokinin A and endothelin produced concentration-dependent contractions of mucosa-free muscle strips from the dome of the human urinary bladder. The maximal response to carbachol or neurokinin A exceeded that to KCl, while the maximal response to endothelin approached that to KCl. 2. Nifedipine (1 microM) abolished the response to KCl, reduced the response to carbachol or neurokinin A but had no effect on the response to endothelin. Bay K 8644 (1 microM) markedly potentiated the response to KCl but had little or no effect on the response produced by the other stimulants. 3. Superfusion of the strips with a nominally calcium (Ca)-free medium containing EDTA (1 mM) for 30 min markedly reduced the response to carbachol, neurokinin A and endothelin, although a small response was still evident at high concentrations. Likewise, after a prolonged (60 min) superfusion of the strips with a high K (80 mM) Ca-free medium plus EDTA (1 mM) these three agonists still produced a small contractile response. 4. The nifedipine (1 microM) resistant response to carbachol, neurokinin A or endothelin was markedly depressed by LaCl3 (1 mM). In contrast, the nifedipine-(1 microM) resistant response to carbachol was not modified by NiCl2 (0.1 mM) or omega-conotoxin (0.1 microM). 5. Caffeine produced divergent effects depending upon the temperature of incubation: a relaxation at 37 degrees C and a concentration-dependent (2.5-20 mM) contraction at 25 degrees C. The latter was markedly inhibited by procaine (3 mM) but unaffected by nifedipine (1 microM). 6. After a prolonged (60 min) superfusion with a high K, Ca-free medium containing EDTA the response to carbachol (100 microM) was abolished by previous exposure to procaine (3 mM). Conversely, the response to endothelin (1 microM) was unaffected by procaine. The response to endothelin in these experimental conditions was also resistant to LaCl3 (1 mM). 7. These findings indicate that multiple sources of Ca are mobilized for contraction of the human bladder muscle by different stimulants. Dihydropyridine- and voltage-sensitive Ca channels provide the major if not the sole source of Ca for the response to KCl, play some role in the response to muscarinic (carbachol) or NK-2 tachykinin receptor stimulation but are not involved in the response to endothelin. Carbachol, neurokinin A and endothelin all mobilize a Ca pool (either extracellular or located at membrane level) which is LaCl3-sensitive but nifedipine-resistant. Neither T- nor N-type channels appear to be involved in the response to carbachol. In addition, these agents mobilize a tightly bound Ca pool independently from membrane depolarization. This latter pool is probably a procaine-sensitive intracellular source of activator Ca mobilized by caffeine and carbachol. The failure of procaine to prevent the response to endothelin in high K, Ca-free medium raises the possibility that this peptide mobilizes an intracellular source of activator Ca, distinct from the caffeine- and carbachol-sensitive pool.
Synthesis of [carboxyl ‐14C] 5 ‐ fluoroorotic acid (1979)

Abstract [Carboxyl ‐ 14 C] 5 ‐ fluoroorotic acid was synthesized by the treatment of [carboxyl‐ 14 C] orotic acid with trifluoromethyl hypofluorite followed by triethyl amine.
Kizamu (2001)

This paper presents Kizamu, a computer-based sculpting system for creating digital characters for the entertainment industry. Kizamu incorporates a blend of new algorithms, significant technical advances, and novel user interaction paradigms into a system that is both powerful and unique.
Neuropharmacology and Drug Interactions in Clinical Practice (1995)

Summary: Absorption, distribution, and clearance are key pharmacokinetic principles. These parameters can be highly variable among patients and among compounds, and are factors that must be considered in the wide variability in response to medications. Current antiepileptic drugs (AEDs) present many challenges in their administration. However, understanding and utilizing pharmacokinetic principles can assist the clinician in the appropriate optimization of AEds.
Electrochemical potential control of charge state and fluorescence of nitrogen vacancy centers in nanodiamonds (2015)

We use spectro-electrochemical microscopy to demonstrate that the equilibrium charge state and fluorescence of nitrogen vacancy centers in nanodiamonds can be dynamically controlled by externally applied potentials.
Characterization ofStreptococcus agalactiaeIsolates of Bovine and Human Origin by Randomly Amplified Polymorphic DNA Analysis (2000)

Streptococcus agalactiae is considered one of the major causes of bovine intramammary infections. It is also found in the vaginas of women without any apparent clinical symptoms, but reports of neonatal infections, causing significant morbidity, are relatively frequent. The aim of this study was to evaluate the genetic diversity of S. agalactiae strains isolated from bovine milk and from asymptomatic women in Québec, Canada, by randomly amplified polymorphic DNA (RAPD) analysis. A total of 185 bovine isolates and 38 human isolates were first serotyped for capsular polysaccharide by double diffusion in agarose gel (bovine isolates) and coagglutination (human isolates). Strains were then studied by RAPD using 3 primers, designated OPS11, OPB17, and OPB18, which were selected from 12 primers. Thirty-eight percent of bovine isolates and 82% of human isolates could be serotyped. Prevalent serotypes were type III (28%) for bovine isolates and types V (26%) and III (24%) for human isolates. RAPD results showed that, taken together, all isolates (of bovine and human origin) shared 58% similarity. Ninety-four percent of these isolates were clustered in four groups (I, II, III, and IV) with 70% similarity among them. Three clusters, A (48 isolates), B (14 isolates), and C (32 isolates), with 79 to 80% similarity were identified within group IV, whereas the three other groups did not present any clusters. Despite some clustering of human isolates, relatively high diversity was seen among them. Relatively high heterogeneity was observed with the RAPD profiles, not only for field strains belonging to different serotypes but also for those within a given serotype.
Temporal Graph Learning for Financial World (2022)

The most intuitive way to model a transaction in the financial world is through a Graph. Every transaction can be considered as an edge between two vertices, one of which is the paying party and another is the receiving party. Properties of these nodes and edges directly map to business problems in the financial world. The problem of detecting a fraudulent transaction can be considered as a property of the edge. The problem of money laundering can be considered as a path-detection in the Graph. The problem of a merchant going delinquent can be considered as the property of a node. While there are many such examples, the above help in realising the direct mapping of Graph properties with the financial problems in the real-world. This tutorial is based on the potential of using Graph Neural Network based Learning for solving business problems in the financial world.
Support For Mir Prototyping And Real-Time Applications In The Chuck Programming Language. (2008)

[TODO] Add abstract here.
Laparoscopic Pyeloplasty for Secondary Ureteropelvic Junction Obstruction (2003)

For secondary ureteropelvic junction obstruction, laparoscopic pyeloplasty can be performed safely with a success rate comparable to that of standard open pyeloplasty. The patient benefits of laparoscopic ureteropelvic junction repair of secondary ureteropelvic junction obstruction are similar to the benefits of laparoscopic repair of primary ureteropelvic junction obstruction.
Dynamic Modeling of Belt Drive Systems: Effects of the Shear Deformations (2006)

Multiribbed serpentine belt drive systems are widely adopted in accessory drive automotive applications due to the better performances relative to the flat or V-belt drives. Nevertheless, they can generate unwanted noise and vibration which may affect the correct functionality and the fatigue life of the belt and of the other components of the transmission. The aim of the paper is to analyze the effect of the shear deflection in the rubber layer between the pulley and the belt fibers on the rotational dynamic behavior of the transmission. To this end the Firbank’s model has been extended to cover the case of small amplitude vibrations about mean rotational speeds. The model evidences that the shear deflection can be accounted for by an elastic term reacting to the torsional oscillations in series with a viscous term that dominates at constant speed. In addition, the axial deformation of the belt spans are taken into account. The numerical model has been validated by the comparison with the experimental results obtained on an accessory drive transmission including two pulleys and an automatic tensioner. The results show that the first rotational modes of the system are dominated by the shear deflection of the belt.
Salvage therapies after failure of Helicobacter pylori eradication with ranitidine bismuth citrate‐based therapies (2000)

One-week OAC is not an optimal second-line therapy when RBC-clarithromycin combinations fail. Quadruple therapy appears to be effective despite repeated failures of clarithromycin-based RBC or proton pump inhibitor therapies.
Transtympanic Delivery of Local Anesthetics for Pain in Acute Otitis Media (2019)

Acute otitis media (AOM) commonly causes pain and distress in children. Existing analgesic ototopical drops have limited effectiveness due to the impermeable nature of the tympanic membrane. We developed a local drug delivery system to provide sustained pain relief in patients with AOM, achieved by applying a single dose of a hydrogel formulation onto the tympanic membrane. Successful drug delivery across intact tympanic membranes was demonstrated using the amino-amide anesthetic, bupivacaine, and a highly potent site 1 sodium channel blocker anesthetic, tetrodotoxin. The chemical permeation enhancers incorporated in the delivery system increased the permeability of the tympanic membrane to the anesthetics considerably. The drug levels measured using a previously developed ex vivo model reflect the potential for highly effective local anesthesia.
Synthesis and Protein Tyrosine Phosphatase Inhibitory Activity of Dephostatin Analogs. (1995)

We have synthesized derivatives of dephostatin, a protein tyrosine phosphatase (PTPase) inhibitor, to study the structure-activity relationships of this inhibitor. Inactive analogs revealed some insight into structural requirements or PTPase inhibitory activity of dephostatin. Both a nitroso group and phenolic hydroxyl groups were found to be essential for the inhibitory activity. Among the dephostatin derivative synthesized, one of the regioisomers of dephostatin showed PTPase inhibitory activity equivalent to that of dephostatin, and also had increased stability.
Cohort Profile: The HealthNuts Study: Population prevalence and environmental/genetic predictors of food allergy (2015)

HealthNuts is a single-centre, multi-wave, population-based longitudinal study designed to assess prevalence, determinants, natural history and burden of allergy (particularly food allergy) in the early years of life. It is novel in the use of serial food challenge measures within its population frame to confirm food allergy. The cohort comprises 5276 children initially recruited at age 12 months from council-run immunization sessions across Melbourne, Australia. As well as parent-completed questionnaires and researcher-observed eczema status, all infants underwent skin-prick testing to egg, peanut, sesame and either cow's milk or shellfish, and those with detectable wheals underwent food challenges to determine clinical allergy. In wave 2, conducted at age 4 years, validated questionnaires collected data on asthma, allergic rhinitis (hay fever), eczema and food allergies. Food challenges were repeated in children previously identified as food allergic to determine resolution. In wave 3, all children (irrespective of food allergy status) were invited for clinical assessment at age 6 years, including lung function, physical measurements, skin-prick testing to foods and aeroallergens and food challenges if food sensitized. Biological specimens (blood, cheek swabs) were collected at each wave for ancillary immunological, genetic and epigenetic studies. Applications to access data and/or samples can be submitted to [katrina.allen@mcri.edu.au].
Electrochemical and Catalytic Properties of Fe-Doped SrCo0.9-xNb0.1FexO3-δCathode Materials (2016)

Fe and Nb substituted perovskite SrCo0.9-xNb0.1FexO3-δ (0 < x < 0.3) are investigated as potential cathode materials for intermediate temperature solid oxide fuel cells (SOFCs) and reversible SOFCs (RSOFC). The material's structural stability, electrical conductivity, electrochemical performance and oxygen exchange kinetics were measured. XRD results show improved structural stability of the cubic perovskite structure with Fe doping. A decrease in the electrical conductivity, as well as an increase in the area specific resistance is observed for increasing values of stoichiometric coefficient x. This affect is attributed to limited mobility of oxygen vacancies with the replacement of Co by Fe, as well as to stronger metal-oxygen bonding. The oxygen surface exchange coefficient under different temperatures and oxygen partial pressures was determined. Highest exchange coefficient values were measured with x = 0 Fe doping. The dependence of exchange coefficient on oxygen partial pressure indicates a dissociative adsorption limited process, with participation of molecular oxygen. Activation energies of exchange process were obtained under two different temperature regimes. These results indicate that SrCo0.9-xNb0.1FexO3-δ (0 < x < 0.3) perovskites maintain their structure at intermediate temperatures and show high catalytic activity toward oxygen reduction, and therefore can serve as potential cathode materials for application in SOFCs and RSOFCs.
CT and MR imaging in Hodgkin's disease – present and future (2005)

Initial staging of Hodgkin's disease is crucial to determine the location and extent of disease, and is the hallmark for the choice of treatment. At present, the established radiological technique for staging Hodgkin's disease is computed tomography (CT). Modern multidetector row CT scanners allow fast imaging from the scull base to the groins during a single breath hold with a spatial resolution of approximately 1 mm. Both, nodal and extranodal involvement of Hodgkin's disease can be diagnosed with CT. Magnetic resonance (MR) imaging is another useful cross-sectional imaging modality for staging Hodgkin's disease. The development of fast MR imaging techniques has considerably reduced imaging time without compromising the quality of MR images. As a consequence, MR imaging is now considered to be as diagnostic as CT for staging Hodgkin's disease. The excellent soft-tissue contrast and the lack of exposure to ionizing radiation are the main advantages of MR imaging. For the detection of extranodal Hodgkin's disease, MR imaging is superior to assess involvement of the brain, the spinal cord and bone marrow; while CT allows excellent evaluation of lung disease. Common major problems in staging Hodgkin's disease are still the detection of nodal involvement in normal sized lymph nodes and residual tumor masses after therapy. In the future, newly developed lymphotropic contrast agents for MR imaging might be helpful to answer these questions.
A multidisciplinary approach to a better understanding of and therapy for chronic obstructive pulmonary disease (2006)

The overall premise of this project is that COPD is a syndrome with considerable heterogeneity regarding the relative contributions of the mechanisms of airflow obstruction. Moreover, differing mechanisms underlying airflow obstruction will have different pathobiology, genetic determinants and responses to therapy and the grouping of all of these patients under the umbrella “COPD” therefore impedes future progress in research and therapy. The best progress will be made when groups of investigators from a variety of basic and clinical research disciplines work together to approach these issues.
Multicast: wired to wireless (2002)

There has been an increasing demand for applications like multiplayer online gaming, where players residing in different parts of the world participate in the same gaming session through the Internet. Multicasting could prove to be an efficient way of providing necessary services for these applications. Furthermore, with the increasing popularity of handheld devices and mobile equipment, it is imperative to determine the best way to provide these services in a wireless environment. Due to very diverse requirements, it is necessary to investigate and discern the applicability of existing multicast protocols and qualify which is more suitable for which types of applications. This article provides a detailed description and comparison of IP-based wired and wireless multicast protocols. We hope that the discussion presented will be helpful to application developers in selecting an appropriate multicast protocol for their specific needs.
Electrospray Formation of Gelled Nano-Aluminum Microspheres with Superior Reactivity (2013)

Nanometallic fuels with high combustion enthalpy, such as aluminum, have been proposed as a potential fuel replacement for conventional metallic fuel to improve propellant performance in a variety of propulsive systems. Nevertheless, nanometallic fuels suffer from the processing challenges in polymer formulations such as increased viscosity and large agglomeration, which hinder their implementation. In this letter, we employ electrospray as a means to create a gel within a droplet, via a rapid, solvent evaporation-induced aggregation of aluminum nanoparticles, containing a small mass fraction of an energetic binder. The gelled aluminum microspheres were characterized and tested for their burning behavior by rapid wire heating ignition experiments. The gelled aluminum microspheres show enhanced combustion behavior compared to nanoaluminum, which possibly benefits from the nitrocellulose coating and the gelled microstructure, and is far superior to the corresponding dense micrometer-sized aluminum.
AIM Process Design Kit (AIMPDKv2.0): Silicon Photonics Passive and Active Component Libraries on a 300mm Wafer (2018)

A new process design kit (AIMPDKv2.0) is introduced that offers a verified silicon photonics component library on 300mm silicon-on-insulator wafers. The library includes multi-layer waveguides, polarization manipulation, switches, filters, and high-speed digital/analog detectors and modulators.
Profiting from New Breeding Techniques: The Latest Technical Seminar Organised Jointly by BCPC and the Farmers Club 11 July 2019 (2019)

This Technical Seminar was the third in a series organised jointly by BCPC and the Farmers Club, explaining the science, benefits, drawbacks and regulatory issues surrounding new breeding technology (NBT). Overall, the author left the seminar with mixed feelings. He felt optimistic that NBTs can make a difference in future development of new crop varieties due to the positive messages from all the speakers on the technology and its benefits. However, the scientists and the other stakeholders in agriculture need to convince the politicians and society in general, that this technology will be critical to feeding the future world and that it can be responsibly and effectively managed so that it poses no threat to man and the environment.
Photonic Integrated Circuits for Optical Routing and Switching Applications (2008)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text M. L. Mašanović, E. F. Burmeister, A. Tauke-Pedretti, B. R. Koch, M. M. Dummer, J. A. Summers, J. S. Barton, L. A. Coldren, J. E. Bowers, and D. J. Blumenthal, "Photonic Integrated Circuits for Optical Routing and Switching Applications," in Integrated Photonics and Nanophotonics Research and Applications, (Optica Publishing Group, 2008), paper IWC5. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
A short and efficient total synthesis of (±) prostaglandin D2methyl ester involving a new method for the cleavage of a dimethyl-t-butylsilyl ether (1981)

Baeyer-Villiger oxidation of the bicyclo[2.2.1]heptanone (4; R = SiMe2But) afforded a mixture of isomeric lactones (5) and (6), the minor component (6) being conveniently removed by selective hydrolysis. Reduction of the lactone (5) by di-isobutylaluminium hydride gave the corresponding lactol (8). Conversion of (8) into the 9α-silyloxyprostanoid (10) was performed so as to minimise silyl group migration. Oxidation of (10) gave the ketone (12) but the hindered siloxy-group at C-9 was extremely resistant to cleavage by the usual reagents. Satisfactory deprotection of (12) was achieved by treatment with aqueous HF in acetonitrile to give (±)-prostaglandin D2 methyl ester (14) and (±)-15-epi-prostaglandin D2 methyl ester (15). The high ‘silicophilicity’ and low acidity of HF make it the reagent of choice for cleavage of silyl ethers under mildly acidic conditions.
Spark Ionization (2016)

This document contains recommendations for terminology in mass spectrometry. Development of standard terms dates back to 1974 when the IUPAC Commission on Analytical Nomenclature issued recommendations on mass spectrometry terms and definitions. In 1978, the IUPAC Commission on Molecular Structure and Spectroscopy updated and extended the recommendations and made further recommendations regarding symbols, acronyms, and abbreviations. The IUPAC Physical Chemistry Division Commission on Molecular Structure and Spectroscopy’s Subcommittee on Mass Spectroscopy revised the recommended terms in 1991 and appended terms relating to vacuum technology. Some additional terms related to tandem mass spectrometry were added in 1993 and accelerator mass spectrometry in 1994. Owing to the rapid expansion of the field in the intervening years, particularly in mass spectrometry of biomolecules, a further revision of the recommendations has become necessary. This document contains a comprehensive revision of mass spectrometry terminology that represents the current consensus of the mass spectrometry community.
Parallel-Coupled Adiabatic Resonant Microring (ARM) Filter with Integrated Heaters (2013)

Add-drop filters based on parallel adiabatic resonant microrings (ARMs) are demonstrated. The ARM design permits synthesis of maximally flat characteristics up to a FWHM of 54 GHz while keeping the ripple amplitude below 1 dB.
Impaired retinal microcirculation in multiple sclerosis (2016)

The impaired retinal microcirculation in RRMS patients indicates microvascular dysfunction in MS.