gebhart/patrepeval huggingface dataset:
Increased myocardial expression of foxp3 and IL-10 in post-myocardial infarction (MI) heart failure (HF) in CCR7 deficient mice. (2015)

&lt;p&gt;Gene expression of CD3γ (&lt;b&gt;A&lt;/b&gt;), foxP3 (&lt;b&gt;B&lt;/b&gt;), IL-10 (&lt;b&gt;G&lt;/b&gt;) and TGF-β&lt;sub&gt;1&lt;/sub&gt; (&lt;b&gt;H&lt;/b&gt;) in LV one and six weeks following sham operation or MI in Wt (1w: n = 7+8; 6w: n = 5+7) and CCR7 deficient (1w: n = 6+9; 6w: n = 8+9) mice (numbers denote sham operation and post-MI HF, respectively). mRNA levels were quantified by real-time RT-PCR and are presented relative to the gene expression of GAPDH. Data are mean±SEM. Panel &lt;b&gt;C&lt;/b&gt;. show average number of foxP3 positive cells in the area bordering the ischemic zone, and panels &lt;b&gt;D&lt;/b&gt; and &lt;b&gt;E&lt;/b&gt; show representative images of immunohistochemical staining of foxP3 in LV tissue from a Wt mouse (&lt;b&gt;D&lt;/b&gt;) and a CCR7&lt;sup&gt;−/−&lt;/sup&gt; mouse (&lt;b&gt;E&lt;/b&gt;) 1 week after MI. Panel &lt;b&gt;F&lt;/b&gt; shows staining with the corresponding isotype control IgG antibody. *p&lt;0.05 versus sham in same genotype; &lt;sup&gt;†&lt;/sup&gt;p&lt;0.05, &lt;sup&gt;††&lt;/sup&gt;p&lt;0.01 and &lt;sup&gt;†††&lt;/sup&gt;p&lt;0.001 versus Wt post-MI HF.&lt;/p&gt;
Multiband perceptual modulation analysis, processing and synthesis of audio signals (2009)

The decomposition of audio signals into perceptually meaningful multiband modulation components opens up new possibilities for advanced signal processing. The signal adaptive analysis approach proposed in this paper will be shown to provide a powerful handle on the signal's perceptual properties: pitch, timbre or roughness can be manipulated straight forward. Additionally a synthesis method is specified providing high subjective perceptual quality. Furthermore, as an application example, a novel audio processing technique is proposed which changes the key mode of a given piece of music e.g. from major to minor key or vice versa.
Effect of Addition of a Diblock Copolymer on Blend Morphology and Performance of Poly(3-hexylthiophene):Perylene Diimide Solar Cells (2009)

The use of a diblock copolymer and a novel dissymmetric perylene leads to improvement in the efficiency of poly(3-hexylthiophene):perylene diimide solar cells. In films with the diblock copolymer, transmission electron micrographs indicate formation of smaller domain sizes, and the photoluminescence of the perylene component is partially quenched.
Far above bandgap photonics: attosecond dynamics of highly excited electrons in materials (2017)

Tabletop-scale coherent EUV generated through high-harmonic generation (HHG) produces light in the form of an attosecond pulse train that uniquely combines characteristics of good energy resolution (&asymp;100-300meV) with sub-fs time resolution. This makes HHG an ideal source for studying the fastest dynamics in materials. Furthermore, using angle-resolved photoemission spectroscopy (ARPES), it is possible to extract detailed information about electron dynamics over the entire Brillouin zone. In recently published work, we combined HHG with ARPES to identify a sub-femtosecond excited-state lifetime for the first time. Photoemission occurs as a three-step process: 1) An electron is photoexcited from the valence band to far above the Fermi energy; 2) it transports to the surface, and 3) it overcomes the work function and exits. If the electron is promoted into a highlyexcited unoccupied band in the material (as opposed to a free-electron-like state), we observe the electron emission lifetime to increase in a measurable way—the Ni band 22 eV above the Fermi level has a lifetime of 212&plusmn;30 attoseconds. Furthermore, by comparing photoemission from Cu and Ni, we reveal the influence of attosecond-timescale electron screening vs scattering by the electrons near the fermi surface. This work for the first time demonstrates the relevance of attosecond spectroscopy to the study of intrinsic properties and band structure in materials, as opposed to the strong-field induced dynamics studied extensively to-date.
ChemInform Abstract: NO Reduction Utilizing Complex Oxide Catalysts. (2016)

Abstract In view of reducing NO x levels in automotive exhaust gases under excess O 2 , a series of Rh, Ir, or Pd‐doped (10 mol%) BaCeO 3 perovskites are prepared by calcination of Ba(NO 3 ) 2 , Ce(NO 3 ) 3 , and IrCl 3 , RhBr 3 , or Pd(NO 3 ) 2 (air, 1000 °C, 46 h).
Thioredoxin and dihydrolipoic acid are required for 3-mercaptopyruvate sulfurtransferase to produce hydrogen sulfide (2011)

H2S (hydrogen sulfide) has recently been recognized as a signalling molecule as well as a cytoprotectant. We recently demonstrated that 3MST (3-mercaptopyruvate sulfurtransferase) produces H2S from 3MP (3-mercaptopyruvate). Although a reducing substance is required for an intermediate persulfide at the active site of 3MST to release H2S, the substance has not been identified. In the present study we show that Trx (thioredoxin) and DHLA (dihydrolipoic acid) associate with 3MST to release H2S. Other reducing substances, such as NADPH, NADH, GSH, cysteine and CoA, did not have any effect on the reaction. We also show that 3MST produces H2S from thiosulfate. The present study provides a new insight into a mechanism for the production of H2S by 3MST.
From Chip to Cooling Tower Data Center Modeling: Influence of Chip Temperature Control Philosophy (2011)

The chiller cooled data center environment consists of many interlinked elements that are usually treated as individual components. This chain of components and their influences on each other must be considered in determining the benefits of any data center design and operational strategies seeking to improve efficiency, such as temperature controlled fan algorithms. Using the models previously developed by the authors, this paper extends the analysis to include the electronics within the rack through considering the processor heat sink temperature. This has allowed determination of the influence of various cooling strategies on the data center coefficient of performance. The strategy of increasing inlet aisle temperature is examined in some detail and found not to be a robust methodology for improving the overall energy performance of the data center, while tight temperature controls at the chip level consistently provide better performance, yielding more computing per watt of cooling power. These findings are of strong practical relevance for the design of fan control algorithms at the rack level and general operational strategies in data centers. Finally, the impact of heat sink thermal resistance is considered, and the potential data center efficiency gains from improved heat sink designs are discussed.
Gesture-based Mobile Communication System Providing Side-by-side Shopping Feeling (2018)

This demo is a gesture-based communication framework designed for an immersive joint shopping scenario. It focuses on enhancing the mobile human-to-human interaction between two geographically separated users: an in-house user and an in-store user. By exploring the uses of depth-based tracking techniques and the integration of head-mounted displays and the spherical camera, we (1) construct an immersive virtual shopping environment for the in-house user remaining in a house and (2) offer a novel way for the users to achieve a real-time gestural communication in the physical shopping environment which the in-store user stays in, while (3) the latter gets an augmented reality experience. Through this demo, both users could share a feeling that they go for shopping side by side in the same place.
Evidence of acceptor-like oxide defects created by hot-carrier injection in n-MOSFET's: a charge-pumping study (1991)

Charge-pumping measurements and simulation of charge-pumping characteristics demonstrate that acceptor-like oxide traps (i.e. negatively charged when occupied by an electron and neutral when occupied by a hole) are created in the gate-drain overlap region of an n-MOSFET subjected to hot-electron and/or hot-hole injections (HEI and/or HHI). These traps are located in the gate-drain overlap region, and it is emphasized that the charge-pumping technique is able to detect them in addition to the damages in the channel.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
The future of inflammatory bowel disease care. (2009)

This article summarizes the David Sun Lecture at the American College of Gastroenterology in Orlando, Florida, that was delivered on October 4, 2008. The lecture, entitled "The Future Direction of IBD Care," reviewed the future use of current drugs (such as 5-aminosalicylate, steroids, immunosuppressive medications, and biologic agents) and upcoming drugs in the treatment of IBD.
Polarization-Dependent Optical Response in Anisotropic Nanoparticle-DNA Superlattices* (2020)

DNA-programmable assembly has been used to prepare superlattices composed of octahedral and spherical nanoparticles, respectively. These superlattices have the same body-centered cubic lattice symmetry and macroscopic rhombic dodecahedron crystal habit but tunable lattice parameters by virtue of the DNA length, allowing one to study and determine the effect of nanoscale structure and lattice parameter on the light–matter interactions in the superlattices. In addition, the micron length scales associated with well-formed superlattices lead to optical cavity modes, such as FP resonances that arise due to interference of light traveling between the parallel top and bottom facets of the superlattice, and shape-dependent scattering that is dictated by the crystal habit. The simulated spectra exhibit a convolution of plasmonic and FP modes, however, the influence of nano- and microscale structure can be disentangled. Backscattering measurements were performed on these super-lattices with a microscope-coupled spectrometer.
Scalable Attestation: A Step Toward Secure and Trusted Clouds (2015)

In this work we present Scalable Attestation, a method which combines both secure boot and trusted boot technologies, and extends them up into the host, its programs, and up into the guest's operating system and workloads, to both detect and prevent integrity attacks. Anchored in hardware, this integrity appraisal and attestation protects persistent data (files) from remote attack, even if the attack is root privileged. As an added benefit of a hardware rooted attestation, we gain a simple hardware based geolocation attestation to help enforce regulatory requirements. This design is implemented in multiple cloud test beds based on the QEMU/KVM hypervisor, Open Stack, and Open Attestation, and is shown to provide significant additional integrity protection at negligible cost.
Functional outcomes and quality of life in patients with brain tumours: a review of the literature (2001)

Brain tumour patients experience changes in function and quality of life during their disease course. Rehabilitation services may offer a unique opportunity to influence both functional outcome and more closely assess quality of life in these individuals.
Bioguided isolation of anticonvulsant principles from Helleborus cyclophyllus using the zebrafish epilepsy model (2016)

In ancient Greece, certain Helleborus species were used to treat a variety of diseases including leprosy, deafness, madness and epilepsy [1]. Hippocrates (˜400 BC) discovered diuretic and emetic properties of the Greek Hellebore Helleborus cyclophyllus Boissier [Ranunculaceae] while in ancient Rome this plant was recommended for curing epilepsy, madness and melancholia [2]. Based on our ethnopharmacological survey, we hypothesized that H. cyclophyllus might reveal novel anticonvulsant natural products. Towards this end, leaves and root extracts of this plant were screened in a zebrafish epilepsy model with seizures induced by the GABAA antagonist pentylenetetrazol [3]. As expected, the methanolic root extract showed a significant inhibition of seizures. In order to target the bioactivity of the active extract, the HPLC analytical conditions were geometrically transferred for a high-scale fractionation on medium-pressure liquid chromatography (MPLC-UV-ELSD). Major compounds from these fractions were isolated by semi-preparative chromatography and identified by HRMS and NMR, including a new saponin. Subsequently, three out of sixteen fractions exhibited potent anticonvulsant activity. Finally, hellebrin and two other saponins showed significant reduction of epileptic seizures on the zebrafish bioassay. Our results report for the first time the anticonvulsant activity of some isolated compounds from Helleborus cyclophyllus and confirmed one of the medicinal use of this ancient Greek plant.
Prostate Cancer: Can Multiparametric MR Imaging Help Identify Patients Who Are Candidates for Active Surveillance? (2013)

Multiparametric MR imaging provides useful additional information to existing clinicopathologic scoring systems of prostate cancer and improves the assignment of treatment (eg, AS or active treatment).
THE SATURNE BUDGET (1959)

The cost of the Saturne accelerator is briefly discussed. The investments made by the conclusion of 1958 are tabulated. The expenses to be incurred in 1959 are briefly considered. (J.S.R.)
Chloë Grace Moretz, el último grito (2013)

Tiene 16 anos y, sin prisas pero pisando fuerte, se esta construyendo una carrera de aupa. Chloe Grace Moretz ha rodado con Martin Scorsese y Tim Burton, ha sido una superheroina repartemamporros, y el cine de terror le va como anillo al dedo. Con Carrie, remake del film de Brian de Palma, dara que hablar. Les presentamos a la adolescente de moda en Hollywood.
Domain Wall Dynamics under Nonlocal Spin-Transfer Torque (2012)

We study spin-diffusion effects within a continuously variable magnetization distribution, integrating with micromagnetics the diffusive model of Zhang and Li [Phys. Rev. Lett. 93, 127204 (2004)]. Current-driven wall motion is, in the steady velocity regime, shown to be adequately described by an effective nonlocal nonadiabatic parameter. This parameter is found to be 20% larger than its local counterpart for a vortex wall in a NiFe nanostrip and hardly modified for a transverse wall. This may account for the yet unexplained experimental evidence that vortex walls move more easily under current when compared with transverse walls. It is shown that this effective parameter can be derived from the domain wall structure at rest.
Programmable photonic integrated meshes for modular generation of optical entanglement links (2023)

Abstract Large-scale generation of quantum entanglement between individually controllable qubits is at the core of quantum computing, communications, and sensing. Modular architectures of remotely-connected quantum technologies have been proposed for a variety of physical qubits, with demonstrations reported in atomic and all-photonic systems. However, an open challenge in these architectures lies in constructing high-speed and high-fidelity reconfigurable photonic networks for optically-heralded entanglement among target qubits. Here we introduce a programmable photonic integrated circuit (PIC), realized in a piezo-actuated silicon nitride (SiN)-in-oxide CMOS-compatible process, that implements an N × N Mach–Zehnder mesh (MZM) capable of high-speed execution of linear optical transformations. The visible-spectrum photonic integrated mesh is programmed to generate optical connectivity on up to N = 8 inputs for a range of optically-heralded entanglement protocols. In particular, we experimentally demonstrated optical connections between 16 independent pairwise mode couplings through the MZM, with optical transformation fidelities averaging 0.991 ± 0.0063. The PIC’s reconfigurable optical connectivity suffices for the production of 8-qubit resource states as building blocks of larger topological cluster states for quantum computing. Our programmable PIC platform enables the fast and scalable optical switching technology necessary for network-based quantum information processors.
Multi-Pinhole SPECT Imaging With Silicon Strip Detectors (2009)

Silicon double-sided strip detectors offer outstanding instrinsic spatial resolution with reasonable detection efficiency for iodine-125 emissions. This spatial resolution allows for multiple-pinhole imaging at low magnification, minimizing the problem of multiplexing. We have conducted imaging studies using a prototype system that utilizes a detector of 300-micrometer thickness and 50-micrometer strip pitch together with a 23-pinhole collimator. These studies include an investigation of the synthetic-collimator imaging approach, which combines multiple-pinhole projections acquired at multiple magnifications to obtain tomographic reconstructions from limited-angle data using the ML-EM algorithm. Sub-millimeter spatial resolution was obtained, demonstrating the basic validity of this approach.
11C-DPA-713 Versus 18F-GE-180: A Preclinical Comparison of Translocator Protein 18 kDa PET Tracers to Visualize Acute and Chronic Neuroinflammation in a Mouse Model of Ischemic Stroke (2018)

Neuroinflammation plays a key role in neuronal injury after ischemic stroke. PET imaging of translocator protein 18 kDa (TSPO) permits longitudinal, noninvasive visualization of neuroinflammation in both preclinical and clinical settings. Many TSPO tracers have been developed, however, it is unclear which tracer is the most sensitive and accurate for monitoring the in vivo spatiotemporal dynamics of neuroinflammation across applications. Hence, there is a need for head-to-head comparisons of promising TSPO PET tracers across different disease states. Accordingly, the aim of this study was to directly compare 2 promising second-generation TSPO tracers, <sup>11</sup>C-DPA-713 and <sup>18</sup>F-GE-180, for the first time at acute and chronic time points after ischemic stroke. <b>Methods:</b> After distal middle cerebral artery occlusion or sham surgery, mice underwent consecutive PET/CT imaging with <sup>11</sup>C-DPA-713 and <sup>18</sup>F-GE-180 at 2, 6, and 28 d after stroke. T2-weighted MR images were acquired to enable delineation of ipsilateral (infarct) and contralateral brain regions of interest (ROIs). PET/CT images were analyzed by calculating percentage injected dose per gram in MR-guided ROIs. SUV ratios were determined using the contralateral thalamus (SUV<sub>Th</sub>) as a pseudoreference region. Ex vivo autoradiography and immunohistochemistry were performed to verify in vivo findings. <b>Results:</b> Significantly increased tracer uptake was observed in the ipsilateral compared with contralateral ROI (SUV<sub>Th</sub>, 50-60 min summed data) at acute and chronic time points using <sup>11</sup>C-DPA-713 and <sup>18</sup>F-GE-180. Ex vivo autoradiography confirmed in vivo findings demonstrating increased TSPO tracer uptake in infarcted versus contralateral brain tissue. Importantly, a significant correlation was identified between microglial/macrophage activation (cluster of differentiation 68 immunostaining) and <sup>11</sup>C-DPA-713- PET signal, which was not evident with <sup>18</sup>F-GE-180. No significant correlations were observed between TSPO PET and activated astrocytes (glial fibrillary acidic protein immunostaining). <b>Conclusion:</b><sup>11</sup>C-DPA-713 and <sup>18</sup>F-GE-180 PET enable detection of neuroinflammation at acute and chronic time points after cerebral ischemia in mice. <sup>11</sup>C-DPA-713 PET reflects the extent of microglial activation in infarcted distal middle cerebral artery occlusion mouse brain tissue more accurately than <sup>18</sup>F-GE-180 and appears to be slightly more sensitive. These results highlight the potential of <sup>11</sup>C-DPA-713 for tracking microglial activation in vivo after stroke and warrant further investigation in both preclinical and clinical settings.
Influence of Donor Age on the Survival of Human Embryonic Dopaminergic Neural Grafts (1992)

This article has no abstract.
Synthesis and properties of the iron(II) complex of a pentadentate ligand derived from diazaoxacyclononane (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and properties of the iron(II) complex of a pentadentate ligand derived from diazaoxacyclononaneWitold S. Szulbinski, P. Richard Warburton, Daryle H. Busch, and Nathaniel W. AlcockCite this: Inorg. Chem. 1993, 32, 3, 297–302Publication Date (Print):February 1, 1993Publication History Published online1 May 2002Published inissue 1 February 1993https://pubs.acs.org/doi/10.1021/ic00055a012https://doi.org/10.1021/ic00055a012research-articleACS PublicationsRequest reuse permissionsArticle Views172Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Towards universal and voltage-scalable high gate- and drain-voltage MOSFETs in CMOS (2009)

This paper introduces a concept of lateral gates located on top of STI regions enabling layout-defined high gate voltages. Through the lateral fringing capacitance, conduction channels are opened also along the sidewalls of the STI regions leading to current flow along these sidewalls. The spacing between poly-Si and STI edge (= layout) determines gate dielectric thickness. Such novel Hybrid MOSFETs with both a high gate voltage and a high drain voltage capability are demonstrated experimentally in foundry baseline 65nm CMOS technology. Gate voltages up to 50V are measured including gate oxide integrity lifetime exceeding 10 years. The manufactured devices deliver current per micron on par with that of an ideal planar MOSFET with an equivalent gate-oxide thickness, but without a need for dedicated manufacturing steps.
1580 nm band, equally-spaced 8 × 10 Gb/s WDM channel transmission over 360 km (3 × 120 km) of dispersion-shifted fiber avoiding FWM impairment (1997)

By using the 1580 nm wavelength band and gain-shifted EDFAs, error-free transmission of 8 × 10 Gb/s WDM channels over 360 km (3 × 120 km) of dispersion-shifted fiber is achieved without any FWM degradation.
RISK FACTORS FOR PLANTAR FASCIITIS (2003)

The risk of plantar fasciitis increases as the range of ankle dorsiflexion decreases. Individuals who spend the majority of their workday on their feet and those whose body-mass index is >30 kg/m (2) are also at increased risk for the development of plantar fasciitis. Reduced ankle dorsiflexion, obesity, and work-related weight-bearing appear to be independent risk factors for plantar fasciitis. Reduced ankle dorsiflexion appears to be the most important risk factor.