gebhart/patrepeval huggingface dataset:
Supplementary Table 4 from Transformation-Dependent Silencing of Tumor-Selective Apoptosis-Inducing TRAIL by DNA Hypermethylation Is Antagonized by Decitabine (2023)

Supplementary Table 4 from Transformation-Dependent Silencing of Tumor-Selective Apoptosis-Inducing TRAIL by DNA Hypermethylation Is Antagonized by Decitabine
Rickettsial Infectious Antibody Complexes: Detection by Antiglobulin Plaque Reduction Technique (1974)

Rickettsia rickettsii and R. australis formed infectious antibody complexes when reacted with homologous convalescent serum. The addition of antiglobulin to these complexes showed neutralization of plaques proportional to the concentration of rickettsial immune serum.
836: Laparoscopic Partial Nephrectomy: Impact of Tumor Location (2005)

You have accessJournal of UrologyPodium, Monday, May 23, 2005, 1:00 - 3:00 pm1 Apr 2005836: Laparoscopic Partial Nephrectomy: Impact of Tumor Location Kyle J. Weld, Ramakrishna Venkatesh, Caroline D. Ames, Richard Vanlangendonck, Robert S. Figenshau, Chandru P. Sundaram, Adam S. Kibel, Ralph V. Clayman, Gerald L. Andriole, and Jaime Landman Kyle J. WeldKyle J. Weld More articles by this author , Ramakrishna VenkateshRamakrishna Venkatesh More articles by this author , Caroline D. AmesCaroline D. Ames More articles by this author , Richard VanlangendonckRichard Vanlangendonck More articles by this author , Robert S. FigenshauRobert S. Figenshau More articles by this author , Chandru P. SundaramChandru P. Sundaram More articles by this author , Adam S. KibelAdam S. Kibel More articles by this author , Ralph V. ClaymanRalph V. Clayman More articles by this author , Gerald L. AndrioleGerald L. Andriole More articles by this author , and Jaime LandmanJaime Landman More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)35005-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "836: Laparoscopic Partial Nephrectomy: Impact of Tumor Location." The Journal of Urology, 173(4S), p. 227 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 173Issue 4SApril 2005Page: 227 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Kyle J. Weld More articles by this author Ramakrishna Venkatesh More articles by this author Caroline D. Ames More articles by this author Richard Vanlangendonck More articles by this author Robert S. Figenshau More articles by this author Chandru P. Sundaram More articles by this author Adam S. Kibel More articles by this author Ralph V. Clayman More articles by this author Gerald L. Andriole More articles by this author Jaime Landman More articles by this author Expand All Advertisement PDF downloadLoading ...
Large-Scale Distributed Storage System for Business Provenance (2011)

In today's complex business environment, applications span across loosely coupled systems generating massive amounts of business artifacts at various levels of granularity. Monitoring and analyzing these artifacts enables access to critical process information to improve the effectiveness of business operations. Tracking, capturing, storing and processing such large volumes of data, however, is difficult and resource intensive with current relational database technologies. Hence, designers are forced to make trade-offs in deciding the type and the granularity level of the data to be captured. Nevertheless, the amount of historical data that carries important insight about the business processes that need to be captured is growing. A solution that is capable of handling massive business provenance data is necessary. In this paper, using cloud as opposed to relational databases to manage this massive amount of business provenance data is proposed and a cloud-based business provenance architecture based on HBase/Hadoop technology is introduced.
Extraordinary optical transmission inside a waveguide: spatial mode dependence (2016)

We study the influence of the input spatial mode on the extraordinary optical transmission (EOT) effect. By placing a metal screen with a 1D array of subwavelength holes inside a terahertz (THz) parallel-plate waveguide (PPWG), we can directly compare the transmission spectra with different input waveguide modes. We observe that the transmitted spectrum depends strongly on the input mode. A conventional description of EOT based on the excitation of surface plasmons is not predictive in all cases. Instead, we utilize a formalism based on impedance matching, which accurately predicts the spectral resonances for both TEM and non-TEM input modes.
High temperature thermoelectric properties of optimized InGaN (2011)

The effects of carrier concentration, composition, and temperature on the thermoelectric properties of high quality n-type InGaN grown by metal organic chemical vapor deposition (MOCVD) were systematically investigated. The Seebeck coefficient was found to decrease and electrical conductivity increase with increasing carrier concentration, while both were found to decrease with increasing indium composition. Additionally, thermal conductivity was found to decrease by over an order of magnitude as indium composition was increased from 0 to 19%. These trends resulted in optimum carrier concentration and indium composition of 1.1×1019 cm−3 and 17%, respectively, with a room temperature ZT of 0.04. Increasing temperature resulted in a rapidly increasing ZT, reaching a maximum value of 0.34 at 875 K. This significantly improved ZT demonstrates the potential of InGaN and other III-Nitride materials for high temperature thermoelectric applications.
Equine Granulosa-Theca Cell Tumors Express Inhibin α- and βA-Subunit Messenger Ribonucleic Acids and Proteins1 (1990)

The association of equine granulosa-theca cell tumors with atrophied contralateral ovaries and abnormal estrous cycles suggests that these tumors produce hormones that affect pituitary gonadotropin production. Because inhibin, a heterodimer protein secreted by granulosa cells, decreases FSH production, we examined the presence of inhibin alpha- and beta A-subunits and their mRNAs in ovarian tumors obtained from three mares. These tumors contained neoplastic cords and nodules, multiple fluid-filled cysts, and a predominance of neoplastic granulosa cells. Reduced proteins from tumor-conditioned media were analyzed by electrophoresis and immunoblotting using antibodies directed against peptide fragments of the alpha- and beta A-chains of porcine inhibin. Specific bands at 50-kDa and 36-kDa for the inhibin alpha-subunit and at 44 kDa and 13 kDa for the inhibin beta A-subunit were observed in these tumors. Northern blot hybridization of 32P-labeled rat inhibin alpha- and beta A-subunit complementary RNAs to total RNA from each tumor revealed predominant bands of activity in all three tumors at 1.5 and 7 kb for the alpha- and beta A-subunit mRNAs, respectively. These results demonstrate that equine granulosa-theca cell tumors express the mRNAs for inhibin alpha- and beta A-subunits and also secrete inhibin subunits that could potentially affect gonadotropin production in afflicted mares. Furthermore, cells derived from these tumors may provide a useful model for understanding inhibin gene regulation and ovarian tumorigenesis.
Polyelectrolyte Complex with Controllable Viscosity by Doping Cu2+ Protects Nylon–Cotton Fabric against Fire (2022)

Nylon-cotton (NC) blend fabrics are widely used in military and industrial applications, but their high flammability still remains a serious problem. In an effort to effectively and quickly impart flame retardancy to the NC fabric, it was treated by simply blade coating with a Cu<sup>2+</sup>-doped polyelectrolyte complex (CPEC) that consists of ammonium polyphosphate (APP), polyethylenimine (PEI), and copper sulfate. The viscosity of the CPEC can be adjusted by altering the content of CuSO<sub>4</sub>, which controls the amount of extrinsic and intrinsic ion pairs. By adjusting the proportion and content of PEI, APP, and CuSO<sub>4</sub>, CPEC suitable for treating the NC fabric was obtained. Only 0.067 wt % Cu<sup>2+</sup> was needed to adjust the viscosity and impart self-extinguishing behavior in a vertical burning test. This simple two-step treatment provides a promising technology to protect flammable polymeric substrates with ultralow metal-doped polyelectrolyte complexes.
Blind Estimation and Suppression of Late Reverberation Utilising Auditory Masking (2008)

A new method for blind estimation and suppression of late reverberation of speech signals is presented. The proposed algorithm consists of two steps. In a first step, the reverberation time is blindly determined from the reverberant signal. Then, an approximation of the power spectrum of late reverberation is subtracted from the power spectrum of the reverberant signal. Hence, a preliminary estimation of the anechoic speech spectrum is derived. In a second step, the auditory masking threshold of the clean spectrum estimation is calculated and used to define the coefficients for a nonlinear filter for the reverberant signal, which produces the final enhanced speech signal. The performance of the algorithm is demonstrated on artificially generated signals. Subjective tests are conducted and their results indicate that the quality of the speech signals obtained by the proposed method is superior when compared to previous methods.
The role of Nodal and Cripto‐1 in human oral squamous cell carcinoma (2020)

Oral squamous cell carcinoma (OSCC) is a common epithelial malignancy of the oral cavity. Nodal and Cripto-1 (CR-1) are important developmental morphogens expressed in several adult cancers and are associated with disease progression. Whether Nodal and CR-1 are simultaneously expressed in the same tumor and how this affects cancer biology are unclear. We investigate the expression and potential role of both Nodal and CR-1 in human OSCC. Immunohistochemistry results show that Nodal and CR-1 are both expressed in the same human OSCC sample and that intensity of Nodal staining is correlated with advanced-stage disease. However, this was not observed with CR-1 staining. Western blot analysis of lysates from two human OSCC line experiments shows expression of CR-1 and Nodal, and their respective signaling molecules, Src and ERK1/2. Treatment of SCC25 and SCC15 cells with both Nodal and CR-1 inhibitors simultaneously resulted in reduced cell viability and reduced levels of P-Src and P-ERK1/2. Further investigation showed that the combination treatment with both Nodal and CR-1 inhibitors was capable of reducing invasiveness of SCC25 cells. Our results show a possible role for Nodal/CR-1 function during progression of human OSCC and that targeting both proteins simultaneously may have therapeutic potential.
Dynamic hetero-metallic bondings visualized by sequential atom imaging (2022)

Traditionally, chemistry has been developed to obtain thermodynamically stable and isolable compounds such as molecules and solids by chemical reactions. However, recent developments in computational chemistry have placed increased importance on studying the dynamic assembly and disassembly of atoms and molecules formed in situ. This study directly visualizes the formation and dissociation dynamics of labile dimers and trimers at atomic resolution with elemental identification. The video recordings of many homo- and hetero-metallic dimers are carried out by combining scanning transmission electron microscopy (STEM) with elemental identification based on the Z-contrast principle. Even short-lived molecules with low probability of existence such as AuAg, AgCu, and AuAgCu are directly visualized as a result of identifying moving atoms at low electron doses.
On the Effects of UE Transceiver Non-Reciprocity in Coordinated TDD Multi-Cell MIMO Network (2014)

In this paper, we study the effects of effective channel non-reciprocity in coordinated TDD multi-cell MIMO network based on weighted sum rate (WSR) maximization. More specifically, we focus on UE transceiver non- reciprocity while the base stations (BS) are assumed to be perfectly calibrated, and both centralized and decentralized beamforming schemes are considered. In the centralized scheme, the cost function is constructed in a central controller using antenna specific UL pilots for channel estimation from all the connected BSs in the network. Then, even though the transceiver frequency response (FR) mismatches at the UE side corrupt the effective channel reciprocity, it is shown to have only a trivial impact on the WSR objective in such centralized case. However, when decentralized beamforming is deployed, the optimization is carried out in each BS and the corresponding cost function and optimization process depend on information acquired by over-the-air signaling between the BSs and all the users using precoded UL pilots. In this case, it is then shown that the transceiver FR mismatches at the UE side can cause severe performance degradation and even influence the convergence properties of the sum-rate optimization process. Further insight is provided for improving the performance by modifying the weight calculations in the optimization process and connecting users with good cell separations. Then a convergence-aware processing algorithm is also proposed to improve the performance of the decentralized scheme under UE transceiver non-reciprocity. Numerical experiments demonstrate that efficient processing algorithms for calibrating UE transceiver mismatches to be less than -30dB to -35dB are, in general, required in the decentralized system in order to achieve performance close to the ideal case without any RF imperfections.
Vicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine Transporter (2013)

Loopy peptides: Peptide turn mimetics of a clinically relevant norepinephrine reuptake inhibitor were developed employing a high-throughput synthesis approach to generate peptide thioesters, with subsequent cyclization through native chemical ligation. The vicinal disulfide constrained cyclic peptidomimetics (see scheme) show high structural and functional similarity to the parent peptide, though with superior metabolic stability. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Cadence analysis of temporal gait patterns for seismic discrimination between human and quadruped footsteps (2009)

This paper reports on a method of cadence analysis for the discrimination between human and quadruped using a cheap seismic sensor. Previous works in the domain of seismic detection of human vs. quadruped have relied on the fundamental gait frequency. Slow movement of quadrupeds can generate the same fundamental gait frequency as human footsteps therefore causing the recognizer to be confused when quadruped are ambling around the sensor. Here we propose utilizing the cadence analysis of temporal gait pattern which provides information on temporal distribution of the gait beats. We also propose a robust method of extracting temporal gait patterns. Features extracted from gait patterns are modeled with optimum number of Gaussian Mixture Models (GMMs). The performance of the system during the test for discriminating between horse, dog, multiple people walk, and single human walk/run was over 95%.
A new method to assess the deformations of internal organs of the abdomen during impact (2014)

NHTSA Workshop 2014, SAN DIEGO, ETATS-UNIS, 09-/11/2014 - 09/11/2014
Synergistic effect of basic fibroblast growth factor and vascular endothelial growth factor in murine hepatocellular carcinoma (2002)

The growth of any solid tumor depends on angiogenesis. Among the known angiogenic factors, basic fibroblast growth factor (bFGF) and vascular endothelial growth factor (VEGF), are potent and representative factors involved in tumor development. It has been reported that bFGF and VEGF showed a synergistic effect in both in vitro and in vivo angiogenesis. However, the interaction of these factors on tumor development and angiogenesis, including hepatocellular carcinoma (HCC), has not yet been elucidated. In this study, we examined the combined effect of bFGF and VEGF overexpression by means of a combination of a retroviral tetracycline (tet)-regulated (Retro-Tet) gene expression system, which can manipulate the gene expression in vivo by providing tet in the drinking water, and a conventional plasmid gene expression system. In an allograft study, bFGF and VEGF overexpression synergistically increased tumor growth and angiogenesis in the murine HCC cells. This synergistic effect also was found in established tumors. VEGF messenger RNA (mRNA) expression in the tumor was increased 3.1-fold by bFGF-overexpression, and the bFGF-induced tumor development was significantly attenuated by treatment with KDR/Flk-1 neutralizing monoclonal antibody. In conclusion, these results suggest that bFGF synergistically augments VEGF-mediated HCC development and angiogenesis at least partly by induction of VEGF through KDR/Flk-1.
ChemInform Abstract: Rational Design of a New Series of Pronucleotide. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A compact electrically-pumped hybrid silicon microring laser (2009)

We demonstrate an electrically-pumped hybrid silicon evanescent microring laser fabricated by a self-aligned process. Low-threshold operation as small as 8.37 mA in continuous-wave (cw) mode is observed due to its compact structure (D=50 μm) and small electrical and optical losses.
Isokinetic evaluation of hip muscles in patients with coxarthrosis (2002)

peer reviewed
Adaptive MC interpolation for memory access reduction in JVT video coding (2003)

The JVT video coding standard (formerly H.26L), employs motion compensation with a 6-tap interpolation filter and variable block sizes. These are among the key features for realizing high compression ratio. However, they are also accompanied by an increase in the computational complexity and number of memory accesses-factors that are critical for real-time implementation of decoders especially for applications with larger frame size such as SDTV or HDTV. In this paper we show that an adaptive "switching" among a bank of interpolation filters can solve this problem. The proposed approximation method for motion estimation at the encoder requires no additional frame memory for switching between interpolation filters. We also present an analysis of the encoder complexity for the proposed method. Simulation results show that the proposed method significantly reduces the number of memory accesses without sacrificing coding efficiency and subjective quality.
Curvilinear structures segmentation in fluoroscopic images (2010)

Fluroscopic imaging provides means to asses the motion of the internal structures and therefore is of great use during surgery. In this report we propose a novel bottom-up approach for the segmentation of curvilinear structures in these images. The main challenge to be addressed is the lack of visual support due to the low SNR where traditional ridge-based methods fail. Our approach combines machine learning techniques, unsupervised clustering and linear programming / discrete optimization. In particular, numerous invariant to position/rotation classifiers are combined to detect candidates pixels of curvilinear structures. These candidates are grouped into consistent geometric segments through the use of a state-of-the art unsupervised clustering algorithm. The complete curvilinear structure is obtained through a linking of these segments using the elastica model in a linear programming framework in a first variant, and using discrete optimization in a second one. Very promising results were obtained on angioplasty guide wire segmentation in cardiac interventional images.
Dynamic energy allocation for coordinated optimization in enterprise workloads (2011)

Power optimization and power control are challenging issues for server computer systems. To obtain power optimization in an enterprise server, one needs to observe temporal behavior of workloads, and how they contribute to relative variations in power drawn by different server components. This depth of analysis helps to validate and quantify various energy/performance trends important for power modeling. In this paper we discuss an adaptive infrastructure to synthesize models that dynamically estimate the throughput and latency characteristics based on component level power distribution in a server. In this infrastructure, we capture telemetry data from a distributed set of physical and logical sensors in the system and use it to train models for various phases of the workload. Once trained, system power, throughput and latency models participate in an optimization heuristics that re-distribute the power to maximize the overall performance/watt of an enterprise server. We demonstrate modeling accuracy and improvement in energy efficiency due to coordinated power allocation among server components.
Polymer Physics and Structure/Property Relationships of Thermally Stable Polyarylene Ethers for Second-Order Nonlinear Optics (1996)

This paper describes the structure/property relationships including the polymer backbone structures and molecular weight, chromophore/polymer interactions, and chromophore functionalization that influence the chromophore orientational dynamics and polymer relaxations in a special class of thermally stable polymers that was recently developed for second-order nonlinear optical applications. These poly(arylene ether) polymers (synthesis and characterization reported elsewhere) are being investigated because of their high glass transition temperatures (>200 °C), which may minimize the randomization of chromophore orientation following electric field poling. They also have hydrogen-bonding sites that can interact with the chromophores, which may improve the temporal stability of chromophore orientation following poling. Generalization of the observed polymer dynamics to other second-order nonlinear optical polymers is discussed. Second harmonic generation, a second-order nonlinear optical effect, and dielectric relaxation are the two techniques employed to examine the intermolecular cooperativity and segmental relaxation behavior in these polymers. By examination of the second-order nonlinear optical properties of the doped or functionalized polymeric material as a function of time and temperature and the dielectric relaxation phenomena as a function of frequency and temperature, information concerning the local mobility and relaxation phenomena of the polymer microenvironment surrounding the nonlinear optical chromophores can be obtained. The dielectric loss data were analyzed using the Havriliak−Negami empirical function and the Schonhals and Schlosser model to examine the extent of intermolecular coupling in these polymer systems. Results obtained using these two techniques are correlated.