gebhart/patrepeval huggingface dataset:
Pathogenic Anti-DNA Antibodies in SLE: Idiotypic Families and Genetic Origins (1990)

We have adopted an idiotypic approach to study the double stranded DNA (dsDNA) binding antibodies of systemic lupus erythematosus (SLE). Three anti-idiotypic reagents, 8.12, 3I, and F4, identify cross reactive idiotypes that are each expressed on anti-dsDNA antibodies in the sera of many patients with SLE. These idiotypic antibodies are implicated in the pathogenesis of SLE as they are present in immune complex deposits in the kidneys of patients with SLE glomerulonephritis. The autoantibody associated idiotypes are also expressed on antibodies that do not bind DNA. We are investigating the origin of the pathogenic anti-dsDNA antibodies of SLE by comparing the autoantibodies, the antibodies to foreign antigens, and the myeloma proteins that express each SLE associated idiotype. In conjunction with serological analysis of these idiotypic systems, molecular genetic studies indicate that both the 8.12 and the 3I autoantibody associated idiotypes may be germline encoded, while the F4 idiotype is generated by somatic mutation. The data further suggest that the antigenic specificity of the pathogenic anti-DNA antibodies of SLE is acquired through somatic mutation of germline immunoglobulin genes. By studying the regulation of genes capable of encoding pathogenic autoantibodies, in both SLE patients and non-autoimmune individuals, we may be able to elucidate the pathogenesis of autoimmune disease and begin to design more effective therapeutic interventions.
Interferometric Sensors Using Internal Fiber Mirrors (1988)

Cost has thus far been a major barrier to the realization of practical interferometric fiber sensor systems. Multiplexing techniques which allow the operation of several sensors with a single laser and photodetector can possibly alleviate this problem. Several sensor multiplexing demonstrations using the Mach-Zehnder configuration have recently been reported.1-3 However, the directional couplers needed for these interferometers are still somewhat expensive and they constitute undesirable mechanical discontinuities in a sensor cable.
A Double-Hybrid Spread-Spectrum Technique for EMI Mitigation in DC-DC Switching Regulators (2010)

Randomizing the switching frequency (RSF) to reduce the electromagnetic interference (EMI) of switching power converters is a well-known technique that has been previously discussed. The randomized pulse position (RPP) technique, in which the switching frequency is kept fixed while the pulse position (the delay from the starting of the switching cycle to the turn-on instant within the cycle) is randomized, has been previously addressed in the literature for the same purpose. This paper presents a double-hybrid technique (DHB) for EMI reduction in dc-dc switching regulators. The proposed technique employed both the RSF and the RPP techniques. To effectively spread the conducted-noise frequency spectrum and at the same time attain a satisfactory output voltage quality, two parameters (switching frequency and pulse position) were randomized, and a third parameter (the duty ratio) was controlled by a digital compensator. Implementation was achieved using field programmable gate array (FPGA) technology, which is increasingly being adopted in industrial electronic applications. To evaluate the contribution of the proposed DHB technique, investigations were carried out for each basic PWM, RPP, RSF, and DHB technique. Then a comparison was made of the performances achieved. The experimentally investigated features include the effect of each technique on the common-mode, differential-mode, and total conducted-noise characteristics, and their influence on the converter’s output ripple voltage.
Induced-emission cross sections in neodymium laser glasses (1974)

A method for calculating induced-emission cross sections in neodymium laser glasses, based on simple absorbance measurements, has been demonstrated. Absorption and emission transition probabilities of four silicate-base neodymium laser glasses have been characterized in terms of the Judd-Ofelt (JO) model of crystal-field-induced electric-dipole transitions. Absolute absorption intensities in 3669A, ED-2, LSG-91H, and S33 glasses were measured and used to determine three phenomenological intensity parameters for each glass which accounted for the measured intensities to within 5 percent (rms). Emission intensities between the metastable <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sup> <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">F_{3/2}</tex> and terminal <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sup> <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">I J</tex> levels were then calculated for each glass, together with the <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sup> <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">F_{3/2}</tex> radiative lifetime, fluorescence branching ratios, and radiative quantum efficiency. Calculated values of these quantities for 3669A and S33 glasses are compared with measured values appearing in the literature. Using experimental line shapes for the <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sup> <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">F_{3/2} \rightarrow</tex> <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sup> <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">I_{11/2}</tex> transitions at 1.06μ, induced-emission cross sections for these glasses were calculated.
Improved photoluminescence efficiency of patterned quantum dots incorporating a dots-in-the-well structure (2008)

InAs quantum dots embedded in InGaAs quantum well (DWELL: dots-in-the-well) structures grown on nanopatterned GaAs pyramids and planar GaAs(001) surface are comparatively investigated. Photoluminescence (PL) measurements demonstrate that the DWELL structure grown on the GaAs pyramids exhibits a broad quantum well PL band (full width at half-maximum ∼ 90 meV) and a higher quantum dot emission efficiency than the DWELL structure grown on the planar GaAs(001) substrate. These properties are attributed to the InGaAs quantum well with distributed thickness profile on the faceted GaAs pyramids, which introduces a tapered energy band structure and enhances carrier capture into the quantum dots.
LP42: COMPARATIVE GENE EXPRESSION ANALYSIS OF REPAIRED AND UNREPAIRED PERIPHERAL NERVES DURING THE EARLY PHASE AFTER NERVE LESION (2010)

1Clinic of Hand, Plastic, Reconstructive Surgery and Burn Unit, BG Trauma Center Tuebingen, Eberhard-Karls-University of Tuebingen, Germany 2Center for Medical Research (ZMF), University of Heidelberg, Germany 3Department of Anesthesiology and Intensive Care Medicine, Medical Faculty Mannheim, University of Heidelberg, Germany
Metal exsolution in Ba(Fe,M)2(PO4)2 (M=Li, Co, Ni): Metal versus alkali cationic mobility (2015)

International audience
Supplementary Table 1 from Modulation of EZH2 Expression by MEK-ERK or PI3K-AKT Signaling in Lung Cancer Is Dictated by Different KRAS Oncogene Mutations (2023)

&lt;p&gt;Summary of the clinicopathological characteristics of the patients with lung adecarcinoma examined for EZH2 expression and KRAS mutations&lt;/p&gt;
Computing the field in permanent-magnet axial-field motors (1994)

A closed-form expression is presented for computing the axial field in the coil region of permanent-magnet axial-field motors. This expression, which is based on a two-dimensional approximation of the motor geometry, takes into account the finite slope of the demagnetization curve of the permanent-magnet. It can be used to perform parametric studies of field strength and to test new numerical methods. It is tested using finite element analysis (FEA).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Renal tubular regeneration from human Amniotic Fluid Stem Cells (2005)

De Filippo, Roger MD; Perin, Laura PhD; Giuliani, Stefano MD; Maeshima, Akito PhD; Jin, Daniel BS; Sedrakyan, Sargis BS; Atala, Anthony Md Author Information
MXene Phase with C3 Structure Unit: A Family of 2D Electrides (2021)

Abstract A new structural phase is discovered for M 2 CO 2 MXenes with M = Sc, Y, La, Lu, Tm, and Ho. The hexagonal carbon layer sandwiched between M atoms, typical for MXenes, is transformed into C 3 trimers with anionic electrons localized in quasi zero‐dimensional lattice spaces in‐between the C 3 units, so the systems can be described as [M 6 C 3 O 6 ] +II : 2e − electrides. The systems are readily ionized into [M 6 C 3 O 6 ] +II with very low ionization energy via an anti‐doping mechanism. It is shown that this new structure of Sc 2 CO 2 can bind multiple lithium atoms, with low migration barriers. The findings indicate that these M 2 CO 2 MXenes with unusual carbon trimers are a new family of 2D electride insulators with the potential for charge storage applications, thermal field emission, and as anode material in lithium batteries.
Impact of femtocells to the WCDMA network energy efficiency (2010)

Energy consumption of mobile access networks has recently received increased attention. The cellular networks do not have considerable share in the overall energy consumption of the ICT (Information and Communication Technology) sector. However, reduction in energy consumption of cellular networks has great importance from economical and environmental perspective. In this paper we focus on the WCDMA energy saving through femtocell deployment. A simple model for the energy consumption per unit area has been derived based on WCDMA downlink load equations. The model is used to investigate the impact of load sharing between femtocells and macrocells on the overall energy consumption of the network. Based on the model we present two examples where two different deployment scenarios have been compared.
Samarium(II) Iodide (2005)

[32248-43-4] I2Sm (MW 404.16) InChI = 1S/2HI.Sm/h2*1H;/q;;+2/p-2 InChIKey = UAWABSHMGXMCRK-UHFFFAOYSA-L (one-electron reducing agent possessing excellent chemoselectivity in reduction of carbonyl, alkyl halide, and α-heterosubstituted carbonyl substrates;1 promotes Barbier-type coupling reactions, ketyl–alkene coupling reactions, and radical cyclizations1) Physical Data: mp 527 °C; bp 1580 °C; d 0.922 g cm−3. Solubility: soluble 0.1M in THF. Form Supplied in: commercially available as a 0.10 M solution in THF. Preparative Methods: typically prepared in situ for synthetic purposes. SmI2 is conveniently prepared by oxidation of Samarium(0) metal with organic dihalides.2 Handling, Storage, and Precautions: is air sensitive and should be handled under an inert atmosphere. SmI2 may be stored over THF for long periods when it is kept over a small amount of samarium metal.
Preparation of Ultrasharp Diamond Tip Emitters by Ion Beam Etching (1997)

Ion-beam milling was used for sharpening of diamond particles on ends of silicon tips. The sharpened diamond samples were used as Jield-electron emitters. I- V characteristics of the emitters were measured. An effect of conditioning of the emitters was observed: after an emitter worked at least during several hours, its current increased for several orders of
Validating Performance Models for Hybrid Power Plant Control Assessment (2019)

The need for simple, but accurate performance models of wind turbine generators (WTGs), photovoltaic (PV) plants, and battery energy storage systems (BESS) for various hybrid power plant (HPP) studies motivates the present work. Particularly, the development and verification stage of HPP controls requires reduced-order models to minimize the complexity and computation effort of simulation platforms. In this paper, such models are proposed, and the most essential parts of the models are validated through field measurements. The models target power system integration studies involving active and reactive power, as well as frequency and voltage regulation where detailed models, as proposed in the standards, can be cumbersome. Field measurements of two Vestas WTGs, one 1-MW PV plant, and one 1-MW/1-MWh BESS are used for model validation. The results show that the WTG and PV performance models correctly estimate the power generation variability according to fluctuations in wind speed and solar irradiance. The BESS performance model provides satisfactory results related to grid-forming control performance and estimation of state-of-charge. The presented validation work enables using the proposed performance models for power system studies and HPP control design in all model-based design stages, that is, preliminary analysis, design, verification, and validation with a high level of confidence.
Inhibition of Rice Virus Transmission by Esfenvalerate and Its Mechanisms (1990)

Synthetic pyrethroid esfenvalerate, reduced the incidence of the rice stripe virus disease transmitted by smaller brown planthoppers, Laodelphax striatellus, in the greenhouse. To make clear the mechanisms preventing virus infection, the effects of esfenvalerate on vectors were investigated. This compound showed a high repellent activity against smaller brown planthopper which is a stripe disease vector, and green rice leafhopper, Nephotettix virescence, which is a tungro vector. Electronic measurement of insect feeding behaviour revealed that 1 ppm of esfenvalerate inhibited the ingestion and salivation of both species. These results suggested that insecticide lethality, repellency and/or activity inhibiting ingestion and salivation behaviour contributes to prevention of virus infection by planthoppers and leafhoppers.
Marketing image categorization using hybrid human-machine combinations (2012)

Marketing instruments with nested, short-form, symbol loaded content need to be studied differently. Image classification in the Web2.0 world can dynamically use a configurable amount of internal and external data as well as varying levels of crowd-sourcing. Our work is one such examination of how to construct a hybrid technique involving learning and crowd-sourcing. Through a parameter called turkmix and a multitude of crowd-sourcing techniques available we show that we can control the trend of metrics such as precision and recall on the hybrid categorizer.
Unique Gain-of-Function of Mutated c-CBL Tumor Suppresor in Myeloid Neoplasms. (2009)

Abstract Abstract 2970 Poster Board II-946 Acquired uniparental disomy (aUPD) is a common feature of myeloid neoplasms, especially myelodysplastic syndromes (MDS) / myeloploriferative neoplasms (MPN). aUPDs preferentially affected several chromosomal arms in distinct subsets of patients, and frequently associated with mutated oncogenes and tumour suppressor genes. Among these, the most common aUPDs are those involving 11q, which defined a unique subset of myeloid neoplasms that were clinically characterized by frequent diagnosis of chronic myelomonocytic leukaemia (CMML) with normal karyotypes. Recently, we and other groups reported that 11qUPD are genetically defined by the presence of homozygous mutations of C-CBL. C-CBL proto-oncogene is the cellular homolog of the v-Cbl transforming gene of the Cas NS-1 murine leukemia virus. C-CBL is thought to be involved in the negative modulation of tyrosine kinase signalling, primarily through their E3 ubiquitin ligase activity that is responsible for the down-regulation of activated tyrosine kinases. As expected from the latter function, we demonstrated that wild-type C-CBL has tumour suppressor functions; c-Cbl null mice showed expanded hematopoietic progenitor pools, promoted blastic crisis induced by a bcr/abl transgene, and spontaneous development of late-onset invasive cancers in complete penetrance. On the other hand, mutated C-CBL showed clear oncogenic potential; all tested mutants strongly transformed NIH3T3 fibroblasts, and prolonged replating capacity of hematopoietic progenitors. All reported C-CBL mutations involved the linker-RING finger domains that are central to the E3 ubiquitin ligase activity. We demonstrated that mutated C-CBL not only lost their E3 ubiquitin ligase activity, but also inhibited that of wild-type C-CBL, leading to prolonged activation of a broad spectrum of tyrosine kinases after ligand stimulations in fibroblasts and hematopoietic cells. In accordance with this, c-Cbl−/− hematopoietic stem/progenitor cells (HSPCs) showed enhanced sensitivity to a variety of cytokines, but unexpectedly, transduction of C-CBL mutants into c-Cbl−/− HSPCs further augmented the sensitivity to a broader spectrum of cytokines, indicating the presence of gain-of-function in mutated C-CBL that is not simply mediated by inhibition of wild-type C-CBL functions. The gain-of-function effects of C-CBL mutants on cytokine sensitivity of HSPCs largely disappeared in the c-Cbl+/+ background or by co-transduction of wild-type C-CBL, which may suggest the pathogenic importance of loss of wild-type c-Cbl alleles found in most cases of C-CBL-mutated myeloid neoplasms. Our findings provide a novel insight into a role of gain-of-function mutations of a tumour suppressor associated with aUPD in the pathogenesis of some of myeloid cancer subsets. Currently, further functional studies regarding the molecular mechanism of the gain-of-function are ongoing. Disclosures: Omine: Alexion: Consultancy, Research Funding.
Blind Estimation of Maximum Delay Spread in OFDM Systems (2006)

We present a new method of estimating the maximum delay spread of a channel in an OFDM system. The method differs from other approaches because it uses all active OFDM subcarriers (pilot and data) and therefore avoids the aliasing problem arising from the exclusive usage of pilot subcarriers. The method considers the transmitted data as a random probe signal for obtaining characteristics of a channel. Although the data content is not known at the receiver, it turns out that useful second order statistics can be extracted, from which the maximum delay spread is estimated. The method is shown to be robust to noise and Doppler spread.
Fully Plastic Actuator through Layer‐by‐Layer Casting with Ionic‐Liquid‐Based Bucky Gel (2005)

Flüssige Filme: Ionische Flüssigkeiten, in denen einwandige Kohlenstoffnanoröhren dispergiert sind (Bucky-Gele), ermöglichten den ersten schichtweisen Aufbau eines vollständig aus Kunststoff bestehenden Aktuators. Dieser Aktuator hat eine einfache Dreischicht-Konfiguration aus weichen Elektroden und Elektrolytschichten (siehe Bild) und kann an Luft bei niedrigen Spannungen betrieben werden.
Reconstruction of Ionospheric Perturbation Induced by 2004 Sumatra Tsunami Using a Computerized Tomography Technique (2009)

A computerized tomography technique is used to reconstruct a 3-D profile of electron density perturbation in the ionosphere based on the total electron content data recorded at a planned GPS receiver network. Simulations are conducted using the data of the 2004 Sumatra event. An effective early-warning system may become feasible based on this work.
ChemInform Abstract: ORGANOACTINIDE PHOSPHINE/PHOSPHITE COORDINATION CHEMISTRY. FACILE HYDRIDE‐INDUCED DEALKOXYLATION AND THE FORMATION OF ACTINIDE PHOSPHINIDENE COMPLEXES (1984)

Abstract Untersuchungen zeigen, daß das aus den Dimethyl‐Analogen (I) gebildete Dihydrid (II) in situ mit Trimethylphosphit unter Bildung der phosphinidenverbrückten Methoxy‐Komplexe (III) und den Dimethoxy‐Komplexen (IV) (keine Ausb.‐ Angabe) reagiert.
Beyond n-grams (1998)

It seems obvious that a successful model of natural language would incorporate a great deal of both linguistic and world knowledge. Interestingly, state of the art language models for speech recognition are based on a very crude linguistic model, namely conditioning the probability of a word on a small fixed number of preceding words. Despite many attempts to incorporate more sophisticated information into the models, the n-gram model remains the state of the art, used in virtually all speech recognition systems. In this paper we address the question of whether there is hope in improving language modeling by incorporating more sophisticated linguistic and world knowledge, or whether the n-grams are already capturing the majority of the information that can be employed.
High temperature continuous-wave operation of 1.3- and 1.55-μm VCSELs with InP/Air-Gap DBRs (2003)

We demonstrate novel electrically pumped 1.3- and 1.55-μm vertical cavity surface emitting lasers (VCSELs) with two InP/air-gap distributed Bragg reflectors (DBRs). The active regions comprise conventional InGaAsP multiple quantum wells. A tunnel junction is placed between the active region and the top DBR to convert electrons into holes, thus minimizing the use of p-type material in the structure to reduce the free-carrier loss and achieve current confinement. The whole structure was grown in a single growth run by low-pressure metal-organic chemical vapor deposition (MOCVD). For both 1.3and 1.55-μm emission wavelengths, air-gap DBR VCSELs exhibit room-temperature continuous wavelength (CW) threshold current density as low as 1.1 kA/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , differential quantum efficiency greater than 30%, and CW operation up to 85°C. The single-mode output power was 1.6 mW from a 1.3 μm VCSEL with a 6.3-μm aperture and 1.1 mW from a 1.55 μm VCSEL with a 5.7-μm aperture under room temperature CW operation.
10,000-hour maintenance-free operation of 1-W femtosecond laser for industrial applications (2006)

We demonstrated stable operation of the femtosecond laser continuously over 10,000 hours only with compensation of power loss of LDs.
ChemInform Abstract: Anion Reactions of 1,3‐Dithiane 1,3‐Dioxide with Carbonyl Compounds: High Diastereoselectivity with Aromatic Aldehydes under Conditions of Equilibrium Control. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.