gebhart/patrepeval huggingface dataset:
Immune deposits formed in situ by a monoclonal antibody recognizing a new intrinsic rat mesangial matrix antigen. (1986)

We describe a unique mesangial matrix component of the rat glomerulus identified by a murine monoclonal antibody. The antigen is present exclusively in the glomerular mesangium and cannot be detected in other rat tissues by indirect immunofluorescence techniques or following pretreatment of tissue sections with acid urea or other nonionic detergents. Specific immunoprecipitation of the solubilized antigen yields a single peptide with an apparent m.w. of 81,000 when analyzed by discontinuous SDS-PAGE. This mesangial matrix component is collagenase resistant and trypsin sensitive. Perfusion of an isolated kidney preparation with this antibody results in direct binding of the mouse immunoglobulin to its mesangial antigen. Passive administration of the monoclonal antibody to Lewis rats results in characteristic electron dense deposits within the mesangial matrix that can be visualized ultrastructurally as early as 3 days. The immune deposits form without the activation of rat complement and persist for longer periods than those that develop after the planting of aggregated proteins or preformed immune complexes. Experimental animals that received either a monoclonal antibody specific for laminin or a non-kidney binding preparation did not develop such immune deposits at any time during the course of the autologous phase of the immune process. The results obtained in this study indicate that electron dense immune deposits can develop in the mesangium with the participation of a unique intrinsic matrix component and specific circulating monoclonal antibodies by an in situ mechanism of immune complex formation.
Sequestration of zearalenone using microorganisms blend in vitro (2023)

Zearalenone (ZEN) is an estrogenic mycotoxin produced by the Fusarium species and induces severe reproductive disorders in animals thus a major concern in the livestock industry. Probiotic bacteria treatments have been shown to inactivate mycotoxins, therefore, in this study, we investigated the effect of two commercial probiotic feed additives on the sequestration of ZEN. Commercial probiotic blends containing clay-based binder with Aspergillus niger, Bacillus licheniformis, Bacillus pumilus, and Bacillus subtilis at various proportions from BioMatrix International were incubated with ZEN in a time-dependent manner and then analyzed by Enzyme-Linked Immunosorbent Assay (ELISA) to quantify unbound ZEN. Sequestration of ZEN was further verified by using MCF-7 cell-based cytotoxicity and/or cell proliferation assays. ZEN, or probiotic mix, was nontoxic to MCF-7 cells. Probiotic blends decreased ZEN concentration by 45% (∼100 μg L-1) and prevented ZEN from inducing MCF-7 cell proliferation (20%-28% reduction). The probiotic feed supplements tested show a potential utility in ZEN neutralization.
Efficient Access to Cyclic Ureas via Pd‐Catalyzed Cyclization. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Phase-coherent frequency comparison of optical clocks using a telecommunication fiber link (2010)

We have explored the performance of 2 "dark fibers" of a commercial telecommunication fiber link for a remote comparison of optical clocks. These fibers establish a network in Germany that will eventually link optical frequency standards at PTB with those at the Institute of Quantum Optics (IQ) at the Leibniz University of Hanover, and the Max Planck Institutes in Erlangen (MPL) and Garching (MPQ). We demonstrate for the first time that within several minutes a phase coherent comparison of clock lasers at the few 10(-15) level can also be accomplished when the lasers are more than 100 km apart. Based on the performance of the fiber link to the IQ, we estimate the expected stability for the link from PTB to MPQ via MPL that bridges a distance of approximately 900 km.
Barrier Height Variation in Ni-Based AlGaN/GaN Schottky Diodes (2017)

In this paper, we have investigated Ni-based AlGaN/GaN Schottky diodes comprising capping layers with silicon-technology-compatible metals such as TiN, TiW, TiWN, and combinations thereof. The observed change in Schottky barrier height of a Ni and Ni/TiW/TiWN/TiW contact can be explained by stress effects induced by the TiW/TiWN/TiW capping layer, rather than by chemical reactions at the metal-semiconductor interface. Secondary-ion mass spectroscopy and transmission electron microscopy techniques, for samples with and without a TiW/TiWN/TiW cap, have been used to show that no chemical reactions take place. In addition, electrical characterization of dedicated samples revealed that the barrier height of Ni/TiW/TiWN/TiW contacts increases after stepwise selective removal of the TiW/TiWN/TiW cap, thus demonstrating the impact of strain.
Real-time parameter identification and integration on deadbeat-direct torque and flux control (DB-DTFC) without inducing additional torque ripple (2015)

This paper is dedicated to exploring real-time parameter identification approaches and their integration with deadbeat-direct torque and flux control (DB-DTFC) without additional torque ripple. By using the voltage model, at medium and high speed ranges DB-DTFC is insensitive to parameters. Performance degrades at low speeds with the rotor time constant errors because the current model is utilized for flux linkage estimation. Two different real-time parameter estimation approaches are developed, including a flux observer-based model reference adaptive system (MRAS) and a pulsating flux injection-based method. Both are experimentally evaluated for how well they mitigate DB-DTFC performance degradation at low speed. For the MRAS-based method, the fundamental components are used for parameter convergence, which does not induce additional torque ripple. For the injection-based method, traditional d-axis pulsating voltage vector injection used in IFOC yields significant torque ripple, particularly at high speed. The proposed pulsating flux injection scheme used in DB-DTFC excites the same magnitude of current harmonics and induces no additional torque ripple over a wide speed range.
Discovery of nicoyamycin A, an inhibitor of uropathogenic Escherichia coli growth in low iron environments (2017)

High-throughput screening and activity-guided purification identified nicoyamycin A, a natural product comprised of an uncommon 3-methyl-1,4-dioxane ring incorporated into a desferrioxamine-like backbone via a spiroaminal linkage. Nicoyamycin A potently inhibits uropathogenic Escherichia coli growth in low iron medium, a promising step toward developing novel antibiotics to treat recalcitrant bacterial infections.
Cell cycle‐dependent characterization of single MCF‐7 breast cancer cells by 2‐D CE (2007)

The composition of single MCF-7 breast cancer cells is characterized using 2-D CE. Individual MCF-7 cells were aspirated into a 30 mum inner diameter fused-silica capillary and lysed by contact with an SDS-containing buffer. Proteins and other primary amines were fluorescently labeled on-column using the fluorogenic dye 3-(2-furoyl)quinoline-2-carboxaldehyde. Labeled components were separated first according to molecular weight using capillary sieving electrophoresis (CSE) and then by MEKC. Analytes were detected in a sheath-flow cuvette using LIF. The expression profiles for MCF-7 cellular homogenate and a single MCF-7 cell are compared. As a proof-of-principle investigation, variation in expression was also compared within and between G1 and G2/M cell cycle phases for MCF-7 cells. Following their treatment with the viable nuclear stain Hoechst 33342, MCF-7 cells were sorted by flow cytometry on the basis of their ploidy. Sorted cells were then analyzed by 2-D CE. The degree of variability was >2.5 times larger between cells of different phases than between cells of the same phase. In typical 1 h 2-D CE separations using MCF-7 cells, over 100 components are resolved.
Neurogenetics of Anxiety Disorders (2002)

This chapter contains sections titled: Introduction Panic Disorder Family Studies Twin Studies Segregation Studies Parent-of-origin Effect Molecular Genetics Phobic Disorders Family Studies Twin Studies Molecular Genetics Obsessive–Compulsive Disorder Family Studies Twin Studies Segregation Studies Molecular Genetics Generalized Anxiety Disorder Family Studies Twin Studies Association Studies: Candidate Genes Post-traumatic Stress Disorder Family Studies Twin Studies Association Studies Concluding Remarks References
Atomic model for theMcenter in InP (1985)

As described by Levinson et al., the metastable M center in electron-irradiated InP is a complex of at least two point defects that exists in two very distinct atomic configurations, one of which has two variants, and that transforms from one configuration to another with a ``large lattice relax- ation'' at low temperatures. When the Fermi level is not too close to either band edge, the complex is net neutral in one configuration and ionized triply positive in the other. We propose a simple atomic model for this center which identifies the neutral configuration as a second-nearest-neighbor antisite-vacancy pair (${\mathrm{V}}_{\mathrm{In}}$${\mathrm{}}^{\mathrm{\ensuremath{-}}}$-${\mathrm{P}}_{\mathrm{In}}$${\mathrm{}}^{+}$${)}^{0}$, and the triply ionized configuration as ${\mathrm{P}}_{\mathrm{In}}$${\mathrm{}}^{+}$ ${\mathrm{V}}_{\mathrm{P}}$${\mathrm{}}^{+}$ ${\mathrm{P}}_{\mathrm{In}}$${\mathrm{}}^{+}$. We identify the ``large lattice relaxation'' as nearest-neighbor hopping of an In vacancy, which was created by the irradiation.
Big data and cloud identity service for mobile authentication (2017)

Increased individual mobility has pushed the modern society needs for a reliable individual identity verification system as a critical component in many transactions in commercial industries, public sectors and government domains. The requirement for an ideal human identity verification is critical to security and prevention of identity fraud. Thus, trusted identity management has become an essential part of contemporary system infrastructure. It is now well accepted that biometrics-the science of identifying a person (or verifying their identity) based on their physiological or behavioral characteristics-can provide significant value when building such systems. Three key cornerstones in a trusted biometrics-based identity system include the following: (a) A trusted identity enrollment process (b) A trusted identity verification process (c) An identity credential management mechanism. In this chapter, we present several emerging developments in mobile biometrics technologies with particular focus on futuristic cognitive authentication systems for enabling large-scale trusted identity management systems based on biometrics and also biometrics identity services in the cloud. Biometrics is excellent mechanisms for the authentication or identification of individuals because of the credential&apos;s uniqueness and persistence almost over the lifetime of the person. Biometric identity services in the cloud enable mobile biometrics wide adoption economically and also take advantages of adjacent technology advancements.
Zirconium complexes of cyclopenta[b]pyridine: synthesis, structure, and olefin polymerization catalysis (2002)

By treatment of Cp*ZrCl3 with the lithium salt of cyclopenta[b]pyridine (LiCpPy) in toluene, the unsymmetrical complex Cp*(η5-CpPy)ZrCl2 was prepared in 32% yield. On the evidence of X-ray crystal structure analysis, the bifunctional CpPy ligand coordinates Zr in an η5-manner rather than via nitrogen. Cyclopenta[b]pyridine turned out to react with Zr(NMe2)4 in toluene to form mono-cyclopentadienyl complex (η5-CpPy)Zr(NMe2)3(Me2NH) in 70% yield. The polymerization of ethylene and the copolymerization of ethylene with 1-hexene or propene catalyzed by Cp*(η5-CpPy)ZrCl2 activated with MAO was studied in detail.
Blind Separation Of Tissues In Multi-Modal Mri Using Sparse Component Analysis (2005)

Publication in the conference proceedings of EUSIPCO, Antalya, Turkey, 2005
Search for direct chargino production in anomaly-mediated supersymmetry breaking models based on a disappearing-track signature in pp collisions at $ \sqrt{s}=7\;\mathrm{TeV} $ with the ATLAS detector (2013)

A bstract A search for direct chargino production in anomaly-mediated supersymmetry breaking scenarios is performed in pp collisions at $ \sqrt{s}=7\;\mathrm{TeV} $ using 4.7 fb −1 of data collected with the ATLAS experiment at the LHC. In these models, the lightest chargino is predicted to have a lifetime long enough to be detected in the tracking detectors of collider experiments. This analysis explores such models by searching for chargino decays that result in tracks with few associated hits in the outer region of the tracking system. The transverse-momentum spectrum of candidate tracks is found to be consistent with the expectation from the Standard Model background processes and constraints on chargino properties are obtained.
A High‐Rate Li–CO2 Battery Enabled by 2D Medium‐Entropy Catalyst (2023)

Adv. Funct. Mater. 2023, 33, 2300814 DOI: 10.1002/adfm.202300814 In the original version of this article, the author's name Jordi Cabana was incorrect. This correction does not affect the conclusions of this article. The authors apologize for any inconvenience caused.
Strukturbasierte Entwicklung von G‐Protein bevorzugenden μ‐Opioidrezeptor Agonisten (2022)

Abstract Der μ‐Opioidrezeptor (μOR) ist das Haupt‐Angriffsziel für opioide Analgetika. Die Aktivierung des μORs initiiert die Signaltransduktion über G‐Protein‐vermittelte Wege und durch β‐Arrestin‐Rekrutierung. μOR‐Agonisten, die bevorzugt die G‐Protein‐vermittelte Signalübertragung aktivieren, weisen deutlich geringere Nebenwirkungen auf. Der Wirkstoff PZM21, welcher durch computergestütztes Docking entdeckt wurde, ist ein solcher funktionell‐selektiver Agonist (biased agonist) des μORs. In dieser Publikation stellen wir die Kryoelektronenmikroskopie‐Struktur (Cryo‐EM‐Struktur) des PZM21 gebundenen μOR im Komplex mit einem G i Protein vor. Strukturbasiertes Wirkstoffdesign brachte eine Vielzahl an PZM21‐Analoga hervor, die einerseits eine noch deutlichere G i ‐Bevorzugung und andererseits, durch ihre höhere Lipophile, eine verbesserte ZNS‐Gängigkeit aufweisen. Darunter zeigt FH210 eine sehr geringe Wirkstärke bei der Arrestin‐Rekrutierung. Wir haben außerdem die Kryo‐EM‐Struktur von FH210, das an den μOR im Komplex mit dem G i ‐Protein gebunden ist, bestimmt und die erwartete Bindungsposition bestätigt. Die strukturellen und pharmakologischen Studien offenbaren einen potenziellen Mechanismus zur Verringerung der β‐Arrestin‐Rekrutierung durch den μOR und versprechen die Entwicklung von Analgetika der nächsten Generation mit weniger Nebenwirkungen.
Forward-looking volumetric intracardiac imaging using a fully integrated CMUT ring array (2009)

Atrial fibrillation is the most common type of cardiac arrhythmia that now affects over 2.2 million adults in the United States alone. Currently fluoroscopy is the most common method for guiding interventional electrophysiological procedures. We are developing a 9-F forward-looking intracardiac ultrasound catheter for real-time volumetric imaging. We designed and fabricated a 64-element 10-MHz CMUT ring array with through-wafer via interconnects. We also designed custom front-end electronics to be closely integrated with the CMUT array at the tip of the catheter for improved SNR. This integrated circuit (IC) is composed of preamplifiers and protection circuitry, and can directly interface a standard imaging system. This multi-channel IC is capable of passing up to ±50-V bipolar pulses. An 8-channel front-end IC was fabricated based on this circuit topology. Additionally, a flexible PCB was designed for the integration of ring array with front-end electronics. We have acquired a PC-based real-time imaging platform and demonstrated real-time imaging with the ring array. We have also shown volume images using off-line full synthetic aperture image reconstruction method. The presented experimental results demonstrate the performance of our forward-looking volumetric intracardiac imaging approach. We are currently working on the final catheter integration and further development of our real-time imaging methods.
Efficient perovskite solar cells by metal ion doping (2016)

Realizing the theoretical limiting power conversion efficiency (PCE) in perovskite solar cells requires a better understanding and control over the fundamental loss processes occurring in the bulk of the perovskite layer and at the internal semiconductor interfaces in devices.
Local sensorimotor control and learning in robotics with organic neuromorphic electronics (2021)

Artificial intelligence applications have demonstrated their enormous potential for complex processing over the last decade, however they still lack the efficiency and computing capacity of the brain. In living organisms, data signals are represented by sensory and motor processes that are distributed, locally merged and capable of forming dynamic sensorimotor associations through volatile and non-volatile connections. Using similar computational primitives, neuromorphic circuits offer a new way of intelligent information processing that makes it possible to adaptively oberserve, anaylze, operate and interact in real-world scenarios [1-6].&#13;\n&#13;\nIn this work we present a small-scale, locally-trained organic neuromorphic circuit for sensorimotor control and learning, on a robot navigating inside a maze. By connecting the neuromorphic circuit directly to environmental stimuli through sensor signals, the robot is able to respond adaptively to sensory cues and consequently forms a behavioral association to follow the way to the exit. The on-chip sensorimotor integration with low-voltage organic neuromorphic electronics opens the way towards stand-alone, brain-inspired circuitry in autonomous and intelligent robotics.
Highly stable silver–platinum core–shell nanowires for H2O2 detection (2021)

Silver nanowire (Ag NW) networks have great potential to replace commercial transparent conducting oxides due to their superior properties in conjunction with their competitive cost, availability and mechanical flexibility. However, there are still challenges to overcome for the large scale utilization of Ag NWs in devices due to oxidation/sulfidation of NWs, which leads to performance loss. Here, we develop a solution-based strategy to deposit a thin platinum (Pt) shell layer (15 nm) onto Ag NWs to improve their chemical, environmental and electrochemical stabilities. Environmental and thermal stabilities of the core-shell NW networks were monitored under different relative humidity conditions (RH of 43, 75 and 85%) and temperature settings (75 °C for 120 hours and 150 °C for 40 hours) and compared to those of bare Ag NWs. Afterwards, stability of core-shell NW networks in hydrogen peroxide was investigated and compared to that of bare Ag NW networks. The potential window for electrochemical stability of the Ag NW networks was broadened to 0-1 V (vs. Ag/AgCl) upon Pt deposition, while bare Ag NWs were stable only in the 0-0.6 V range. Moreover, Ag-Pt core-shell NWs were used for the detection of hydrogen peroxide, where a high sensitivity of 0.04 μA μM<sup>-1</sup> over a wide linear range of concentrations (16.6-990.1 μM) with a low detection limit (10.95 μM) was obtained for the fabricated sensors. All in all, this highly effective and simple strategy to improve the stability of Ag NWs will certainly open new avenues for their large-scale utilization in various electrochemical and sensing devices.
Corrigendum: Clinical Protocol for a Longitudinal Cohort Study Employing Systems Biology to Identify Markers of Vaccine Immunogenicity in Newborn Infants in The Gambia and Papua New Guinea (2020)

Corrigendum on: Idoko OT, Smolen KK, Wariri O, Imam A, Shannon CP, Dibassey T, DirayArce J, Darboe A, Strandmark J, Ben-Othman R, Odumade OA, McEnaney K, Amenyogbe N, Pomat WS, Haren S, Sanchez-Schmitz G, Brinkman RR, Steen H, Hancock REW, Tebbutt SJ, Richmond PC, van den Biggelaar AHJ, Kollmann TR, Levy O, Ozonoff A and Kampmann B (2020)Guinea. Front. Pediatr. 8:197. doi: 10.3389/fped.2020.00197.In the original article, there was an omission in the legend for Figure 2 as published. 'FW' in the figure stands for Field worker. The correct legend appears below. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
Memory Efficient 3D Integral Volumes (2013)

Integral image data structures are very useful in computer vision applications that involve machine learning approaches based on ensembles of weak learners. The weak learners often are simply several regional sums of intensities subtracted from each other. In this work we present a memory efficient integral volume data structure, that allows reduction of required RAM storage size in such a supervised learning framework using 3D training data. We evaluate our proposed data structure in terms of the tradeoff between computational effort and storage, and show an application for 3D object detection of liver CT data.
Synthesis of dissymmetric phosphorus dendrimers using an unusual protecting group (2018)

We report the synthesis of neutral and polycationic dissymmetric phosphorus dendrimers bearing branches of different generations on the core.
Highly Purified Silane Gas for Advanced Silicon Semiconductor Devices (1998)

Highly purified gas is required for manufacturing silicon semiconductor devices (e.g., the formation of Si‐single crystal, poly‐Si, , and siliside thin films. We have newly established a technology for delicately measuring impurities in gas by using a modified atmospheric pressure ionization mass spectrometer equipped with a two‐compartment ion source, with a lower detection limit around 0.1 to 1 ppb. We have succeeded in establishing the quantitative analysis method for disiloxane in gas by developing a new technology for generating a standard gas. This is a perfect reaction between and in the reactor. Its lower detection limit is 1 ppb. This analysis technology clarified that and changed rapidly into molecules containing oxygen atoms in the cylinder or supply tubing system (i.e., disiloxane, trisiloxane, ... and particles). Therefore, this result shows that the impurities in gas to be controlled are not but siloxane and particles. Based on this technology, we have completed development of technology for manufacturing high purity gas free from , siloxane, and particles. In addition, we have established a technology for delivering highly purified gas to the point of use. It is expected that enhanced wafer yield and higher quality thin film will be ensured in the silicon semiconductor device manufacturing process.
A Flipping UHF RFID Sensor-Tag for Metallic Environment Compliant With ETSI/FCC Bands (2020)

A novel dual-band ultrahigh-frequency (UHF) radio frequency identification (RFID) sensor tag, designed to operate on metallic surfaces, is proposed. This particular UHF RFID sensor tag is capable of operating in both the main RFID frequency bands of the European Telecommunications Standards Institute (ETSI) and the Federal Communication Commission (FCC). The dual-band operation of the UHF RFID sensor tag is based on a very simple concept; by flipping the UHF RFID sensor tag on a metallic surface, it can operate either in the ETSI or FCC RFID frequency bands. The impedance and radiation characteristics of the UHF RFID sensor tag are presented with an extensive analysis of the effects of the metallic surface on the UHF RFID sensor tag. In addition, an equivalent model of the UHF RFID sensor tag, which includes the effects of the metallic surface on the sensor tag, is proposed. The UHF RFID sensor tag has a small form factor and presents a satisfying read range of around 3 m for both the operating frequency bands in a metallic environment as well as a read range of 1.4 m when operating in free space.