gebhart/patrepeval huggingface dataset:
Analytical results on block length optimization for decode-and-forward relaying with CSI feedback (2007)

We consider block length optimization for collaborative transmit diversity using a decode-and-forward protocol assuming that the source and the relay have access to the magnitudes of all path gains. Moreover, we propose a simple scheme which requires only one bit of channel state information (CSI) feedback. We analyze the outage probabilities of all schemes for both selection combining and maximum ratio combining (MRC) at the destination. Analytical results show that even one bit of CSI feedback can provide a signifi cant gain over conventional (non-adaptive) collaborative schemes.
In Vivo Enhancement of Dendritic Cell Function (2004)

Despite the apparent positive recognition of antigen by mucosal T cells after ingesting food, the default functional response in the gut is tolerance. Although dendritic cells (DCs) are classically defined as potent stimulatory antigen-presenting cells, we have previously shown that tolerance is enhanced in vivo in the presence of elevated numbers of DCs. In order to more closely investigate the mechanistic basis of tolerance induction, we have focused our subsequent studies on identifying features peculiar to mucosal dendritic cells and the functional involvement of mucosal DCs in driving the early T cell response to fed antigen. These studies have revealed a population of DCs in the mucosae that exhibit the plasmacytoid phenotype and secrete IFN-alpha following stimulation with CpG, and can drive differentiation of naive T cells into cells that exhibit regulatory properties. The activity of these DCs also failed to sustain robust T cell proliferation and, rather, functioned to enhance the suppressive efficacy of CD4(+)CD25(+) T regulatory cells. Given their significant presence in mucosal tissue, these DCs likely provide a mechanistic basis for the homeostatic regulation prominent in the gut, presumably by eliciting regulatory cell suppressor function and poorly supporting T helper cell proliferation. These studies further underscore the critical role for intestinal DCs in promoting tolerogenic antigen presentation at a site of high antigenic stimulation.
Performance of the Swanton multiple sclerosis criteria for dissemination in space (2010)

New diagnostic criteria for multiple sclerosis (MS) have been proposed by Swanton and co authors, but were not yet evaluated in patients suspected of MS, but diagnosed with another disease. The dissemination in space (DIS) criterion of these Swanton criteria was investigated in such a patient group and compared with the present McDonald criteria. We found that with the Swanton criteria for DIS, simplicity can be combined with some gain in sensitivity, without major loss of specificity.
Molecular Basis of Heavy-Chain Class Switching and Switch Region Deletion in an Abelson Virus-Transformed Cell Line (1984)

We demonstrated that a subclone of an Abelson murine leukemia virus-transformed B-lymphoid cell line switched from mu to gamma 2b expression in vitro, by the classical recombination-deletion mechanism. In this line, the expressed VHDJH region and the C gamma 2b constant region gene were juxtaposed by a recombination event which linked the highly repetitive portions of the S mu and S gama 2b regions and resulted in the loss of the C mu gene from the intervening region. An additional recombination event in this subclone involved an internal deletion in the S mu region of the expressed (switched) allele. One end of this deletion occurred very close to the switch recombination point. Despite the recombination-deletion mechanism of switching, the gamma 2b-producing line retained two copies of the C mu gene and two copies of the sequence just 5' to the S gamma 2b recombination point. The possible significance of the retention of these sequences to the mechanism of class switching is discussed.
A specification invariant technique for operation cost minimisation in flow-graphs (2002)

In high-level synthesis, optimising area, time, and power in real-time applications are the prime objectives. A new model and technique are proposed, which minimise a weighted operation cost function for data-paths at an early stage in the synthesis process. The main target domain consists of lowly-multiplexed and hard-wired implementations of real-time DSP applications. The behavioral specification of an application is translated into a signal flow-graph, the operation cost (area/power) of which is minimised using algebraic transformations. A minimal set of elementary transformations are combined in a flexible way into composite transformations, which are used in an ascent/steepest descent search algorithm. Experiments show that this approach achieves optimal or close to optimal results with very few transformations. The technique is invariant to changes in the specification, as long as these retain the bit-true input/output behaviour.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Applications of High-Dimensional Chaotic Dynamics to Complex Computational Systems (2011)

Novel computational systems different in principle from the von Neumann‐type digital computers have long been investigated. As one of possible candidates for such novel computational systems, we outline a paradigm for a computation through a complex system in this paper. In particular, we address a complex computational system that utilizes high‐dimensional analog physical chaotic dynamics suggested by the interactions between conscious and subconscious processes in the brain. Applications of the proposed system to combinatorial optimization are also given. In addition, we exploit many fixed points embedded in chaotic attractors with density of real‐number, and fractal structures of the high‐dimensional chaotic systems, in order to realize dynamical analog memories with a large memory capacity.
Solution behavior of PEO : the ultimate biocompatible polymer. (2004)

Poly(ethylene oxide) (PEO) is the quintessential biocompatible polymer. Due to its ability to form hydrogen bonds, it is soluble in water, and yet is uncharged and relatively inert. It is being investigated for use in a wide range of biomedical and biotechnical applications, including the prevention of protein adhesion (biofouling), controlled drug delivery, and tissue scaffolds. PEO has also been proposed for use in novel polymer hydrogel nanocomposites with superior mechanical properties. However, the phase behavior of PEO in water is highly anomalous and is not addressed by current theories of polymer solutions. The effective interactions between PEO and water are very concentration dependent, unlike other polymer/solvent systems, due to water-water and water-PEO hydrogen bonds. An understanding of this anomalous behavior requires a careful examination of PEO liquids and solutions on the molecular level. We performed massively parallel molecular dynamics simulations and self-consistent Polymer Reference Interaction Site Model (PRISM) calculations on PEO liquids. We also initiated MD studies on PEO/water solutions with and without an applied electric field. This work is summarized in three parts devoted to: (1) A comparison of MD simulations, theory and experiment on PEO liquids; (2) The implementation of water potentials into the LAMMPS MD code; and (3) A theoretical analysis of the effect of an applied electric field on the phase diagram of polymer solutions.
Appendix A: Rigorous Theory of Diffraction (2009)

This appendix contains sections titled: Maxwell' Equations Wave Propagation and the Wave Equation Towards a Scalar Field Representation References
Supplementary Figure 7 from Enhanced Cancer Radiotherapy through Immunosuppressive Stromal Cell Destruction in Tumors (2023)

&lt;p&gt;PDF file - 1272K, Characterization of the antigen-specific CD8+ T cell-mediated apoptosis of CD11b+ F4/80+ TAMs from irradiated tumors with/without intratumoral vaccination with antigenic peptide.&lt;/p&gt;
TapSkin (2016)

The touchscreen has been the dominant input surface for smartphones and smartwatches. However, its small size compared to a phone limits the richness of the input gestures that can be supported. We present TapSkin, an interaction technique that recognizes up to 11 distinct tap gestures on the skin around the watch using only the inertial sensors and microphone on a commodity smartwatch. An evaluation with 12 participants shows our system can provide classification accuracies from 90.69% to 97.32% in three gesture families -- number pad, d-pad, and corner taps. We discuss the opportunities and remaining challenges for widespread use of this technique to increase input richness on a smartwatch without requiring further on-body instrumentation.
Relative Detection Limit (2016)

This document contains recommendations for terminology in mass spectrometry. Development of standard terms dates back to 1974 when the IUPAC Commission on Analytical Nomenclature issued recommendations on mass spectrometry terms and definitions. In 1978, the IUPAC Commission on Molecular Structure and Spectroscopy updated and extended the recommendations and made further recommendations regarding symbols, acronyms, and abbreviations. The IUPAC Physical Chemistry Division Commission on Molecular Structure and Spectroscopy’s Subcommittee on Mass Spectroscopy revised the recommended terms in 1991 and appended terms relating to vacuum technology. Some additional terms related to tandem mass spectrometry were added in 1993 and accelerator mass spectrometry in 1994. Owing to the rapid expansion of the field in the intervening years, particularly in mass spectrometry of biomolecules, a further revision of the recommendations has become necessary. This document contains a comprehensive revision of mass spectrometry terminology that represents the current consensus of the mass spectrometry community.
Semi-Automated Reconstruction of Curvilinear Structures in Noisy 2D images and 3D image stacks (2013)

We propose a new approach to semi-automated delineation of curvilinear structures in a wide range of imaging modalities. Earlier approaches lack robustness to imaging noise, do not provide radius estimates for the structures and operate only on single channel images. In contrast, ours makes use of the color information, when available, and generates accurate centreline location and radius estimates with minimal supervision. We demonstrate this on a wide range of datasets ranging from a 2D dataset of aerial images to 3D micrographs of neurites.
Fourier-transform Raman studies of secondary structure in synthetic polypeptides (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFourier-transform Raman studies of secondary structure in synthetic polypeptidesV. Hallmark and J. F. RaboltCite this: Macromolecules 1989, 22, 1, 500–502Publication Date (Print):January 1, 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://doi.org/10.1021/ma00191a099RIGHTS & PERMISSIONSArticle Views62Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alerts Get e-Alerts
Sexual and Relationship Intimacy Among Women with Provoked Vestibulodynia and Their Partners: Associations with Sexual Satisfaction, Sexual Function, and Pain Self-Efficacy (2013)

Women's self-reported sexual and relationship intimacy in the couple relationship may promote higher sexual satisfaction, sexual function, and pain self-efficacy, as well as possibly foster greater sexual well-being among women with PVD. The authors discuss implications for the inclusion of emotional and interpersonal aspects of the couple's dynamic in clinical interventions and future research in PVD.
Immunoglobulin E antibodies of atopic individuals exhibit a broad usage of VH‐gene families (2000)

The term 'atopy' describes the genetically determined tendency to mount immunoglobulin E (IgE) antibody responses against per se harmless antigens (allergens). In this study we investigated the usage of VH families in the formation of IgE antibodies in 10 patients suffering from mucosal and/or skin manifestations of atopy. IgE antibody reactivities to exogenous allergen sources as well as to autoallergens were determined and, by immunoabsorption, it was demonstrated that allergen-specific IgE accounted for most of the total serum IgE levels in these patients. Using primers with specificity for the VH1-6 gene families and a primer specific for the first constant region of human IgE, cDNAs coding for IgE heavy chain fragments were amplified using the reverse transcription-polymerase chain reaction (RT-PCR) from peripheral blood lymphocytes of the 10 atopic individuals. Hybridization of the heavy chain-encoding cDNAs with an IgE-specific internal oligonucleotide probe revealed a broad usage of all VH-gene families in the atopic individuals. The spectrum of VH families used in a given atopic individual was neither associated with the type or severity of clinical symptoms nor with the number of allergens recognized. The fact that allergen-specific IgE antibodies in atopic individuals originate from a broad variety of B cells thus reflects the activation of multiple B-cell clones during allergen sensitization. This finding should be borne in mind if therapeutic strategies for Type I allergy are considered that aim at a clonal elimination of allergen-specific B cells.
Peritoneal Macrophage-Specific TNF-α Gene Silencing in LPS-Induced Acute Inflammation Model Using CD44 Targeting Hyaluronic Acid Nanoparticles (2016)

The main goal of this study was to evaluate tumor necrosis factor-alpha (TNF-α) gene silencing in peritoneal macrophages upon activation with lipopolysaccharide (LPS), using CD44-targeting hyaluronic acid (HA)-based nanoparticles encapsulating TNF-α-specific small interfering RNA (siTNF-α). HA nanoparticles were formulated by blending hyaluronic acid-poly(ethylene imine) (HA-PEI), hyaluronic acid-hexyl fatty acid (HA-C6), and hyaluronic acid-poly(ethylene glycol) (HA-PEG) in 3:2:1 weight ratio, and encapsulating siTNF-α to form spherical particles of 78-90 nm diameter. Following intraperitoneal (IP) administration in LPS-treated C57BL/6 mice, the nanoparticles were actively taken up by macrophages and led to a significant downregulation of peritoneal TNF-α level. Downregulation of peritoneal macrophage-specific TNF-α also had a significant impact on other pro-inflammatory cytokine and chemokine levels in the serum. The C57BL/6 group of mice challenged with 5 mg/kg LPS had a significantly higher survival rate when they were treated with 3 mg/kg siTNF-α, either prior or simultaneously with the LPS administration, as compared to the LPS-challenged mice, which were treated with controls including the scrambled siRNA formulation. Overall, the results of this study demonstrate that CD44 targeting HA nanoparticles can selectively deliver siTNF-α to peritoneal macrophages leading to downregulation of pro-inflammatory cytokines in the peritoneal fluid and in the serum. This RNAi strategy could potentially provide an important therapeutic modality for acute inflammatory diseases, such as septic shock.
III-V/Silicon Photonics for Optical Interconnects: Bonding Technology and Integrated Devices (2007)

The heterogeneous integration of III-V components and silicon-on-insulator waveguide circuits using DVS-BCB adhesive die-to-wafer bonding is presented. Advances in the fabrication of laser diodes and photodetectors in the bonded epitaxial layer structure are reported.
Minor Role of Bystander Tolerance to Fetal Calf Serum in a Peptide-specific Dendritic Cell Vaccine Model Against Autoimmunity (2008)

Dendritic cells (DCs) are currently considered as promising tools for vaccination against tumors and also autoimmune responses. A major point of concern has been the use of fetal calf serum (FCS) as a source of heterologous antigen in DC cultures. FCS peptides can be presented by the DCs and cause T-cell responses in the recipient. We investigated the role of FCS in an autoimmune model where DC injections can prevent peptide-specifically from experimental autoimmune encephalomyelitis (EAE). We show that murine bone marrow-derived DCs generated in FCS-containing or serum-free media resulting in a similar phenotype, maturation potential, and functions. Peptide-specific protection could be achieved similarly with FCS-DC or serum-free DCs. Although FCS-DC induced strong CD4 T cell proliferation and cytokine production against FCS, these T cells lack antigenic recall during EAE. Even if FCS was reinjected, the effect on EAE resulted only in a 3-day delay of disease onset. Together, our data show that presentation of bystander antigens by peptide-specific DC vaccinations may have little influence on T-cell responses in vivo if the bystander antigen cannot be recalled by specific T cells.
Oxidation Behavior of Mo-Si-B In Situ Composites (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
A Comparison of Supination and Elbow Flexion Strength in Patients with either Proximal Biceps Release or Biceps Tenodesis (SS‐40) (2006)

Arthroscopic proximal biceps tenotomy and tenodesis are two techniques used to treat symptomatic patients with biceps pathology. We have found little functional difference between patients who have had biceps release versus tenodesis, and have observed that patients with biceps release recover quicker. No studies have evaluated strength in patients who have had an elective proximal biceps release. The purpose of this study was to establish normal data for flexion and supination and compare this to groups of patients who have had either a biceps tenodesis or release.
The Emerging Role of Telomerase Reverse Transcriptase in Mitochondrial DNA Metabolism (2010)

Telomerase is a reverse transcriptase specialized in telomere synthesis. The enzyme is primarily nuclear where it elongates telomeres but recent reports have shown that it also localizes to mitochondria. The function of TERT in mitochondria is largely unknown but the available findings point to a role in mitochondrial DNA metabolism. This paper discusses the available data on mitochondrial telomerase with particular emphasis on its effects upon the organellar DNA.
Phenyl boronic acid complexes of diols and hydroxyacids (2009)

Cumulative formation constants for the interaction of phenyl boronic acids with 1,2-diols and structurally related α-hydroxy carboxylic acids were determined by potentiometric titration in aqueous solution. Although there is a significant electronic effect on the acidity of phenyl boronic acid (ρ = 2.1), there is no marked electronic effect on the stability of the complexes. Rather, the complexes are significantly destabilised by adjacent anionic groups, by steric interactions across the face of the cyclic boronate ester and by angle strain within the boronate ester ring. Binding that is nearly independent of pH is observed for some favourably constituted α-hydroxy acid complexes as a result of the relatively high acidity of the acids, which in turn allows tetrahedral boronate complexes to persist in acidic solution (pH < 3). Boronate complex stability is remarkably sensitive to steric and electrostatic factors.
Seashells as a natural model to study ceramic-polymer composites (1989)

Interests in ceramic/polymer composites are increasing mainly because of their superior physical properties for structural and electronic applications. Naturally produced composites, such as seashells, are ideal to study the formation, microstructure, and physical properties of these composites as these materials have far superior properties with well-defined microstructures than man-made ones which require complex fabrication techniques. In this paper, a summary of a recent study on the microstructure of abalone shell (Haliotis refuscens) will be described in conjunction with its mechanical properties. A longitudinal cross-section of abalone shell displays two types of microstructures: outer prismatic layer and inner nacreous layer . Two forms of CaCO 3 , calcite (rhombohedral, ) and aragonite (orthorhombic, Pmcn) constitute the inorganic component of the organic/ceramic composite in the prismatic and nacreous layers, respectively. The structure and properties of the nacreous will be described here as this is the part which provides a good combination of mechanical properties for the seashell.
Efficacy of an oral CRTH2 antagonist (AZD1981) in the treatment of chronic rhinosinusitis with nasal polyps in adults: A randomized controlled clinical trial (2022)

In patients with CRSwNP, the addition of AZD1981 to intranasal corticosteroids did not change nasal polyp size, radiographic scores, symptoms, or disease-specific quality of life.
Book reviews (1991)

Orlando Figes, Peasant Russia, Civil War. The Volga Countryside in Revolution (1917–1921). Oxford: Clarendon Press, 1989. Pp.xix + 401; illustrations; maps; tables; indexes. A. Venkov, Pechat’ surovogo iskhoda. K istorii sobytii 1919 g. na Verkhnem Donu, Rostov on Don, 1988.
Dihydroisocoumarin Content and Phenotyping of Hydrangea macrophylla subsp. serrata Cultivars under Different Shading Regimes (2021)

Hortensias (Hydrangea macrophylla L.) are well known as ornamental plants with their impressive flowers. Besides being an ornamental plant, some hortensia species contain constituents of nutritional and pharmaceutical interest. In this context, H. macrophylla subsp. serrata contains dihydroisocoumarins (DHCs), in particular hydrangenol (HG) and phyllodulcin (PD), which determine produce quality. For the successful cultivation of H. macrophylla subsp. serrata, shading may be required. The response of H. macrophylla subsp. serrata as a source for DHCs was investigated in two growing seasons using three different cultivars (‘Amagi Amacha’, ‘Oamacha’ and ‘Odoriko Amacha’) under three different light conditions: no shade (100% photosynthetic active radiation, PAR), partial (72% PAR) and full shading (36% PAR). The shading regimes had no significant effect on dihydroisocoumarin content in leaf dry matter in each single cultivar. However, ‘Amagi Amacha’ and ‘Oamacha’ yielded significantly higher PD content in comparison to ‘Odoriko Amacha’, which showed, in contrast, the significantly highest HG content. The total biomass was not significantly affected by the shading regime, but slightly higher biomass was observed under partially shaded and full-shade conditions. Hyperspectral vegetation indices (VIs) and color measurements indicate less vital plants under no shade conditions. While lighting is an important growth factor for hortensia production, DHC is cultivar dependent.