gebhart/patrepeval huggingface dataset:
Is Body Size Estimation Viewpoint Invariant? (2018)

Previous research on own body size estimation has only looked at estimates made by comparing own body size to a test body in front view (e.g., Mölbert et al. 2017). However, people constantly see and compare themselves to bodies in different viewpoints. Depending on the viewpoint, shape cues potentially used to judge body size, such as the waist-to-hip ratio or the overall body outline, vary. Here, we asked whether viewpoint influences estimates of own body size in female participants. For each participant, a personalized female avatar was generated using weight, height, inseam, and arm span, and then variations of the personalized avatar having different weights (±5%, ±10%, ±15%, ±20%, and ±25%) were created using a statistical body model. These eleven test bodies were presented in life-size in immersive virtual reality in six viewpoints: 0°, ±45°, ±90°, 180°. In a one-alternative forced choice paradigm, participants were asked to judge whether the test body was thinner or fatter than themselves. Results showed no significant influence of viewpoint on either the accuracy of body size estimation (PSE) or the sensitivity to weight changes (JND). Across all viewpoints, participants on average slightly overestimated their body weight (3.1%) and could detect a weight difference of 5.2% in 50% of the trials. To further investigate whether females are also able to estimate own body size when the shape of the test bodies is clearly different to theirs, a set of personalized male avatars was generated for each participant and presented in front view using the same task. There was no difference in results between female and male test bodies. These results suggest that people are rather good at extracting body size independent of the viewpoint, and also from bodies with a very different shape. Meeting abstract presented at VSS 2018
New Approximate 2DOF Digital Controller for DC-DC Converter with Additional Zeros (2007)

Robust DC-DC converter which can cover extensive load changes and also input voltage changes with one controller is needed. Then the demand to suppressing output voltage change becomes still severer. We proposed an aproximate 2DOF digital controller which realizes the start-up response and dynamic load response independently. The controller makes the control bandwidth wider, and at the same time makes a variation of the output voltage small at sudden changes of loads and the input voltages. In this paper, a new approximate 2DOF digital controller using additional zeros is proposed. The new controller makes a variation of the output voltage more small at sudden changes of loads and the input voltages. This controller is actually implemented on a DSP and is connected to a DC-DC converter. Experimental studies demonstrate that this type of digital controller can satisfy given severe specifications.
A study of multichannel noise reduction linear filters in the time domain (2011)

We propose a new study of multichannel time-domain noise reduction filters where we decompose the noise-free microphone array observations into two components: the first is correlated with the target signal and perfectly coherent across the sensors while the second consists of residual interference. Then, alternative formulations of well known time-domain filters, namely, the minimum variance distortionless response (MVDR), the linearly constrained minimum variance (LCMV), the multichannel tradeoff, and Wiener filters are given. Besides, the performance of these time-domain filters are analytically investigated and new insights are presented. Numerical results are finally provided to corroborate our study.
Specializing Object-Oriented RPC for Performance and Functionality. (1996)

We found that ADC values were significantly correlated with PFS as well as with MGMT promoter methylation status. We believe that ADC values may merit further investigation as a noninvasive biomarker for predicting treatment response.
Foundations of Neurocardiology: Neural control of the normal and diseased heart (2012)

Neurons in the intrinsic cardiac and intrathoracic extracardiac networks of the cardiac neuronal hierarchy form distinct nested feedback loops that act in concert with central feedback loops in the spinal cord, medulla and higher centers to coordinate regional cardiac function. Intrathoracic ganglia contain afferent, local circuit (interneurons) and sympathetic efferent postganglionic neurons. Cardiac‐related parasympathetic efferent postganglionic neurons are confined to intrinsic cardiac ganglia. The peripheral aspects of this hierarchy are, in turn, modulated by central neurons and circulating neurohumoral agents such as Ang II and catecholamines. Imbalances in cardiac neurohumoral control, especially those leading to excessive efferent neuronal activation, can lead to adverse short‐ or long‐term alterations in cardiac function. These involve structural and functional changes within the intrinsic cardiac nervous system, as well as cardiac arrhythmia induction and pump failure. We have proposed that stabilization of imbalances within select elements of the cardiac neuronal hierarchy can i) reduce the arrhythmogenic potential of cardiac tissues and ii) act to maintain myocyte viability in the presence of regional ischemia. Thus, the cardiac neuronal hierarchy has emerged as a novel therapeutic target for managing cardiac disease via pharmacological, physical or electrical means. HL71830
Ranibizumab for Edema of the Macula in Diabetes Study (2012)

clinicaltrials.gov Identifier:NCT00407381
Broadband Macromodels for Retarded Partial Element Equivalent Circuit (rPEEC) Method (2007)

The partial element equivalent circuit (PEEC) method is, nowadays, widely used in electromagnetic compatibility and signal integrity problems in both the time and frequency domains. Similar to other integral-equation-based techniques, its time domain implementation may suffer from late time instabilities, especially when considering delays [(Lp,P,R,tau)PEEC] (rPEEC). The cause of the instabilities may be either the numerical technique used for the time integration or problems created by the discrete representation of the electromagnetic continuous problem. In this paper, we concentrate on the latter and show that frequency dispersion plays an important role and must be taken into account in order to preserve accuracy and mitigate instabilities issues. An enhanced formulation of the PEEC method is presented that is based on a more accurate computation of partial elements describing the electric and magnetic field couplings; broadband macromodels are generated incorporating the frequency dependence of such elements, thus, allowing us to obtain better stability properties of the resulting (Lp,P,R,tau)PEEC model. The proposed equivalent circuits resemble those of the standard PEEC formulation but are able to capture the dispersion that, when neglected, might contribute to inaccuracies and late time instabilities
All-optical flip-flops using electrically pumped microdisk lasers integrated on silicon (2010)

We demonstrate flip-flop operation using the directional bistability in ultra-small microdisks (7.5 μm diameter) heterogeneously bonded on a silicon chip. The pulse energies are only 1.8 fJ and the bias current is 3.5 mA.
Sophomore course development in power system analysis with interactive MATLAB modules (2002)

This paper presents a course in power systems analysis developed for offer at the sophomore level as part of the required undergraduate electrical engineering curriculum at Iowa State University. We describe the criteria used in developing the course, the topical coverage and a set of computer modules, developed to facilitate learning of particularly difficult concepts while heightening student interest, that run in the MATLAB environment.
Geographic Distribution and Genetic Variability of Hepatitis Delta Virus Genotype I (1997)

Three genotypes of hepatitis delta virus (HDV) have been identified, each with different geographic distributions and disease associations. To better define the geographic distribution and genetic variability of HDV genotype I, and to evaluate the extent of genome variability in populations with different patterns of HDV infection, we have analyzed the sequence of HDV RNA in the sera of 72 patients from different areas. Patients were primarily residents of the United States and areas in and around Greece, including Archangelos, Rhodes. All sequences obtained belonged to HDV genotype I, confirming the wide geographic distribution of this genotype and its predominance in Europe and the United States. In contrast to previous studies, phylogenetic analysis of this large and diverse group of sequences, along with all available previously published HDV sequences, showed no well-defined subtypes within genotype I. Low sequence diversity was found for isolates from the United States, Archangelos, Turkey, and Albania, suggesting that HDV was introduced more recently and/or from fewer sources into these areas as compared to mainland Greece, Italy, and north Africa, where sequence diversity is much greater. The low sequence diversity among isolates from Archangelos is particularly interesting in light of the unusually mild pattern of HDV disease found in this community. Comparison of nucleic acid and amino acid sequences within and among genotypes indicated both highly conserved regions as well as genotype-specific sequences that could be related to functional differences. The most distinctive of the latter was that corresponding to the C-terminal 19-20 amino acids of the long form of hepatitis delta antigen, which is highly conserved within each genotype but considerably diverged among them.
Curious Case of BiEDOT: MALDI-TOF Mass Spectrometry Reveals Unbalanced Monomer Incorporation with Direct (Hetero)arylation Polymerization (2020)

Homocoupling defects in conjugated polymers often go undetected but may cause significant batch-to-batch variations that ultimately give seemingly identical polymers different material properties. These defects may go easily unnoticed because conjugated polymers are commonly characterized via gel-permeation chromatography and elemental analysis, two techniques that are not able to provide information on monomer incorporation or end groups. Nuclear magnetic resonance spectroscopy has provided evidence of homocoupling defects, but is limited to polymeric repeat units with distinct chemical shifts and little spectral overlap, a luxury unavailable in polymeric dioxythiophenes. Here, matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS) was used to characterize different dioxythiophene copolymer (PE2) batches based on 3,4-propylenedioxythiophene (ProDOT) and 2,2′-bis-(3,4-ethylenedioxy)thiophene (biEDOT) to elucidate changes in structure within different polymer batches. It was determined through the analysis of MALDI-TOF mass spectra that excess biEDOT is incorporated into PE2 when using standard direct (hetero)arylation polymerization (DHAP) conditions. It is hypothesized that the high nucleophilicity of biEDOT causes uncontrolled concerted metalation–deprotonation steps in the DHAP catalytic cycle at high temperatures. To improve control of the biEDOT incorporation, the reaction temperature was lowered from 140 to 80 °C, and a different polymerization procedure was used where the reaction temperature was ramped-up from room temperature. Ultimately, incorporation of excess biEDOT was advantageous to the conductivity of oxidatively doped polymer films, with values greater than 200 and 80 S/cm for the high- and low-temperature polymerizations, respectively. This work correlates small differences in polymer structure with solid-state conductivity to expose how batch-to-batch variations regarding homocouplings can produce different material properties.
A TES-based model for compressed "Star Wars" video (2002)

This paper presents a stochastic model for the variable bit rate (VBR) video of the entire "Star Wars" movie under a JPEG-like compression. The goal of this work is to develop a methodology for constructing a suite of high-fidelity source models of full-motion video as a traffic benchmark suitable for driving realistic Monte Carlo simulations of broadband telecommunications networks (ATM based B-ISDN). To this end, a transform-expand-sample) TES-based modeling methodology was employed, subject to fidelity criteria requiring the simultaneous capture of both first-order and second-order statistics. The entire movie was modeled as a Markov renewal modulated TES (MRMT) process with class-dependent holding times. The modeling results support the efficacy of the modeling methodology and suggest that high-fidelity compact source models of full-motion video can be developed by applying this methodology to other types of movies under a variety of coding schemes.
Magnetic resonance imaging planning in children with complex congenital heart disease – A new approach (2017)

3D-PM shows similar results compared to 2D-PM, but allows faster and offline planning thereby reducing the scan time significantly. As newly developed high-resolution 3D datasets can also be used further improvement of this technology is expected.
MEMS Tunable VCSEL with Concave Mirror using the Selective Polishing Method (2006)

We have proposed a micromachined tunable vertical cavity surface emitting laser fabricated using the selective polishing method and two chip bonding. The MEMS-VCSEL consists of a micromachined SOI substrate with concave figure and a half VCSEL chip. The MEMS chip and the half VCSEL chip are bonded together with a narrow gap between them using the metal thermo compression bonding method. Wavelength tuning is achieved electrostatically by applying voltage between silicon membrane and silicon substrate. We have obtained wide tuning range without a mode-hop and sidemode suppression are about 32 nm and 40 dB respectively
Multiparameter Longitudinal Imaging of Immune Cell Activity in Chimeric Antigen Receptor T Cell and Checkpoint Blockade Therapies (2022)

Longitudinal multimodal imaging presents unique opportunities for noninvasive surveillance and prediction of treatment response to cancer immunotherapy. In this work we first designed a novel granzyme B activated self-assembly small molecule, G-SNAT, for the assessment of cytotoxic T lymphocyte mediated cancer cell killing. G-SNAT was found to specifically detect the activity of granzyme B within the cytotoxic granules of activated T cells and engaged cancer cells <i>in vitro</i>. In lymphoma tumor-bearing mice, the retention of cyanine 5 labeled G-SNAT-Cy5 correlated to CAR T cell mediated granzyme B exocytosis and tumor eradication. In colorectal tumor-bearing transgenic mice with hematopoietic cells expressing firefly luciferase, longitudinal bioluminescence and fluorescence imaging revealed that after combination treatment of anti-PD-1 and anti-CTLA-4, the dynamics of immune cell trafficking, tumor infiltration, and cytotoxic activity predicted the therapeutic outcome before tumor shrinkage was evident. These results support further development of G-SNAT for imaging early immune response to checkpoint blockade and CAR T-cell therapy in patients and highlight the utility of multimodality imaging for improved mechanistic insights into cancer immunotherapy.
Preparation, Properties, Protein Cross-Linking and Biodegradability of Plasticizer-Solvent Free Hemp Fibre Reinforced Wheat Gluten, Glutenin, and Gliadin Composites (2014)

The present study is aimed at evaluating the use of plant-based polymers and fibres for the production of sustainable biocomposites. For the first time, plasticiser/solvent-free hemp fibre-reinforced wheat gluten and hemp-gliadin and glutenin composites were obtained by compression moulding at different temperatures. The plasticiser/solvent-free sample preparation method developed in this study facilitated the use of a powdered protein matrix with a mat of randomly oriented hemp fibres. The tensile and protein cross-linking properties, as well as the biodegradability, were investigated. The addition of hemp fibre to the protein matrix increased the E-modulus by 20 to 60% at 130 °C. An increase in moulding temperature from 110 to 130 °C resulted in an increase in maximum stress due to the formation of intermolecular bonds between protein chains. The gliadin composites had higher E-modulus and maximum stress and showed a larger increase in protein polymerisation with increased temperature compared to the glutenin composites. A comparison of tensile properties revealed that the composites were stiffer and stronger compared to several similarly produced biobased composites. The composites were found to be fully biodegradable under a simulated soil environment after 180 days. Biocomposites produced in the present study were found to be environmentally friendly with fairly good mechanical properties.
Design and performance of diffractive optics for custom laser resonators (1995)

Diffractive optical elements are used as end mirrors and internal phase plates in an optical resonator. A single diffractive end mirror is used to produce an arbitrary real-mode profile, and two diffractive mirrors are used to produce complex profiles. Diffractive mirror feature size and phase quantization are shown to affect the shape of the fundamental mode, the fundamental-mode loss, and the discrimination against higher-order modes. Additional transparent phase plates are shown to enhance the modal discrimination of the resonator at the cost of reduced fabrication tolerances of the diffractive optics. A 10-cm-long diffractive resonator design is shown that supports an 8.5-mm-wide fundamental mode with a theoretical second-order mode discrimination of 25% and a negligible loss to the fundamental mode.
Passive imaging of localized reflectors and interfaces in open media (2006)

Previous experiments in open media showed the possibility of reconstructing the direct (ballistic) wave between two passive sensors from the time correlations of elastic or acoustic scattered wave fields. Here we illustrate how the passive imaging technique can also retrieve detailed features of the Green’s function, beyond the ballistic wave. Two ultrasonic experiments are presented. In the first one we reconstruct the complete signature of two well-separated scatterers with a perfect distribution of distant sources. In the second experiment we image an aluminum/water interface with only a few sources. The lack of sources is compensated for by taking advantage of a multiple scattering slab.
Transformation by simian virus 40 induces virus-specific, related antigens in the surface membrane and nuclear envelope (1977)

Nucleus- and mitochondrion-free membranes from hamster lymphocytes transformed by simian virus 40 (SV40), GD248 cells, cause guinea pigs to produce immune sera that reveal the presence in GD248 plasma membranes and mitochondria of two types of glycoprotein that are not detected in membranes of normal lymphocytes [Schmidt-Ullrich, R., Thompson, W. S. & Wallach, D. F. H. (1977) Proc. Natl. Acad. Sci. USA 74, 643-647]. Indirect immune fluorescence of living, SV40-transformed T19 hamster reticulum cells, Balb/c 3T3 mouse fibroblasts, and W18 VA2 human fibroblasts, using the antisera against GD248 membrane, at 4 degrees produced a distinct cell surface fluorescence; however, above 20 degrees , staining at the nuclear perimeter, the SV40 U-antigen reaction, becomes equally prominent. In SV40-transformed cells that had been fixed in cold acetone, as well as in purified GD248 nuclei, thermostable U-antigen staining is dramatic, but there is no reaction for nuclear T-antigen. Rabbit antisera against T19 cells gave immunofluorescence reactions equivalent to those obtained with the antisera against GD248 cells. Normal guinea pig or rabbit sera and cells that had not been transformed by SV40 gave no reaction. Our sera from tumor-bearing hamsters gave only nuclear T-antigen fluorescence. The results indicate the presence of related, SV40-specific antigens in the surface membranes, nuclear envelope, and possibly other intracellular organelles of SV40-transformed cells.
Computational bifurcation and stability studies of the 8: 1 thermal cavity problem (2002)

Abstract Stability analysis algorithms coupled with a robust Newton–Krylov steady‐state iterative solver are used to understand the behavior of the 2D model problem of thermal convection in a 8: 1 differentially heated cavity. Parameter continuation methods along with bifurcation and linear stability analysis are used to study transition from steady to transient flow as a function of Rayleigh number. To carry out this study the steady‐state form of the governing PDEs is discretized using a Galerkin/least‐squares finite element formulation, and solved on parallel computers using a fully coupled Newton method and preconditioned Krylov iterative linear solvers. Linear stability analysis employing a large‐scale eigenvalue capability is used to determine the stability of the steady solutions. The boundary between steady and time‐dependent flows is determined by a Hopf bifurcation tracking capability that is used to directly track the instability with respect to the aspect ratio of the system and with respect to mesh resolution. The effect of upwinding stabilization terms in the finite element formulation on the computed value of critical Rayleigh number is investigated. The Hopf bifurcation signaling the onset of flow is determined to occur at a critical Rayleigh number of Ra =3.0604×10 5 . Copyright © 2002 John Wiley &amp; Sons, Ltd.
Dimensionnement du fronthaul 5G : c'est simple comme un coût de file (2018)

International audience
Rapid separation of bacteriorhodopsin using a laminar-flow extraction system in a microfluidic device (2010)

A protein separation technology using the microfluidic device was developed for the more rapid and effective analysis of target protein. This microfluidic separation system was carried out using the aqueous two-phase system (ATPS) and the ionic liquid two-phase system (ILTPS) for purification method of the protein sample, and the three-flow desalting system was used for the removal of salts from the sucrose-rich sample. Partitioning of the protein sample was observed in ATPS or ILTPS with the various pHs. The microdialysis system was applied to remove small molecules, such as sucrose and salts in the microfluidic channel with the different flow rates of buffer phase. A complex purification method, which combines microdialysis and ATPS or ILTPS, was carried out for the effective purification of bacteriorhodopsin (BR) from the purple membrane of Halobacterium salinarium, which was then analyzed by sodium dodecyl sulfatepolyacrylamide gel electrophoresis and matrix-assisted laser desorptionionization time-of-flight. Furthermore, we were able to make a stable three-phase flow controlling the flow rate in the microfluidic channel. Our complex purification methods were successful in purifying and recovering the BR to its required value.
Signal propagation in dipole coupled nanomagnets for logic applications (2012)

As conventional Silicon-based transistors reach their scaling limits, novel devices for performing computations have emerged as alternatives to continue the improvements in information technology that have benefited society over the past 40 years. One candidate that has shown great promise recently is a device that performs logical computations using dipole coupled nanomagnets. In this paper, we discuss recent advances that have led to a greater understanding of signal propagation in nanomagnet arrays. In particular, we highlight recent experimental work towards the imaging of a propagating magnetic cascade.