gebhart/patrepeval huggingface dataset:
Characterization of anin vivomodel for the study of eyelash biology and trichomegaly: mouse eyelash morphology, development, growth cycle, and anagen prolongation by bimatoprost (2010)

This study shows that mouse eyelashes offer an excellent in vivo model for the quantitative and qualitative analysis of eyelash morphology, development, growth cycle, exogen and pharmacological modulation. This model will help to elucidate the unknown molecular controls of eyelash growth, and to develop novel drugs to treat eyelash disorders.
<title>Polarization dynamics in ferroelectric perovskite crystals</title> (1993)

The polar low frequency vibrational and relaxational modes crucial to understanding the structure and phase transitions of ferroelectric perovskite crystals are examined using impulsive stimulated Raman scattering (ISRS). At wavevectors near the Brillouin zone center, these modes are strongly coupled to light, and the pure optic mode behavior is deduced from the wavevector dependence of the mixed phonon-polaritons.
Three-Dimensional Superlocalization Imaging of Gliding Mycoplasma mobile by Extraordinary Light Transmission through Arrayed Nanoholes (2015)

In this paper, we describe super-resolved sampling of live bacteria based on extraordinary optical transmission (EOT) of light. EOT is produced by surface plasmon confinement and coupling with nanostructures. Bacterial fluorescence is excited by the localized fields for subdiffraction-limited sampling. The concept was applied to elucidating bacterial dynamics of gliding Mycoplasma mobile (M. mobile). The results analyzed with multiple M. mobile bacteria show individual characters and reveal that M. mobile undergoes a significant axial variation at 94 nm. The sampling error of the method is estimated to be much smaller than 1/10 of the diffraction limit both in the lateral and depth axis. The method provides a powerful tool for investigation of biomolecular dynamics at subwavelength precision.
Efficient evaluation of right-, left-, and multi-linear rules (1989)

We present an algorithm for the efficient evaluation of a useful subset of recursive queries. Like the magic sets transformation, the algorithm consists of a rewriting phase followed by semi-naive bottom-up evaluation of the resulting rules. We prove that on a wide range of recursions, this algorithm achieves a factor of Ο(n) speedup over magic sets. Intuitively, the transformations in this algorithm achieve their performance by reducing the arity of the recursive predicates in the transformed rules.
Optical properties of chlorin e6 in living melanoma cells (2020)

The tetrapyrrole chlorin e6 (Ce6) is actively used in photodynamic therapy (PDT) and as a test drug for sonodynamic therapy due to its ability to generate singlet oxygen. In this work, we have analyzed the absorption, photoluminescence (PL), and PL excitation spectra of Ce6 molecules in a nutrient medium and inside the melanoma cells. An analysis of the results shows that Ce6 inside the cancer cells with a low pH remains in monomeric form. A photodynamic test has also been conducted that confirmed the photodynamic effect produced by Ce6 in cancer cells by changing the signals from Ce6 and cells in the absorption and PL spectra.
Demo Abstract: Phase-Gain IC Based Novel Design of Tidal Breathing Pattern Sensor for Pulmonary Disease Diagnostics (2017)

This paper demonstrates a system capable of capturing directionaltidal breathing (inhale/exhale cycles) pattern for application inpulmonary disease diagnostics. The work particularly highlightsintelligent usage of commercially available Analog Device’s phasegainIC and ultrasound to build such a system which otherwiserequires many fold, more complex circuits/electronics to achievesimilar sensitivity. This makes the system compact, affordable yetvery sensitive so that it can be reliably used for tidal breathing analysis,a new trend that emerged recently as opposed to traditionalSpirometric test (based on forced breathing) that is both tedious andpainful for patients with pulmonary obstructions. This work mayturn out quite useful in needy geographies as pulmonary ailmentslike Chronic Obstructive Pulmonary Disease (COPD) is rapidlybecoming an epidemic and requires immediate attention
SOA based all-optical threshold (2000)

Summary form only given.The aim of this communication is to present an all-optical threshold device based on cross-gain modulation (XGM) in SOA's. The simple scheme we are proposing employs two semiconductor optical amplifiers (SOA) optical inverters in a feedback configuration, leading to an all-optical circuit which operates both as threshold and comparator. Analysis of the device operation and further experimentations are presented and discussed.
ChemInform Abstract: CLAISEN REARRANGEMENT OF 7‐CINNAMYLOXY‐5‐HYDROXYISOFLAVONES (1979)

Abstract Die Claisen‐Umlagerung der aus dem Isoflavon (Ia) erhaltenen Verbindung (IIIa) verläuft regiospezifisch zu den isomeren Verbindungen (IV) (Z: ‐H; nach Acetylierung Z: ‐Ac).
Thermal Stability of Type II Modifications by IR Femtosecond Laser in Highly-Doped Aluminosilicate Glass Optical Fibers (2021)

Mastering thermal stability of fiber Bragg gratings (FBGs) in the high temperature regime (>800 °C) have drawn considerable attention for sensing applications. Most components (such as FBGs) fabricated to operate at high temperatures are inscribed into conventional fibers and can usually survive for a short amount of time (few 10’s hours) at temperatures beyond 1000 °C. Therefore, there is a need to develop novel solutions to go beyond these limitations, which ultimately are set by the intrinsic nature of the major glass component (GeO 2 -SiO 2 ). In this context, we investigate the effect of Al 2 O 3 incorporation into the fiber core on the thermal stability of imprinted Type II structures by fs-laser [1] . Aluminosilicate fibers were fabricated using the molten core method. Two fibers labelled High-AS and Low-AS, with a maximum concentration of 51.5 mol% Al 2 O 3 and 42.5 mol% Al 2 O 3 were investigated together with SMF28 for comparison.
Tunable Infrared Pixels via Monolithically Integrated Dynamic Graphene Metasurfaces (2019)

Abstract not provided.
Multihop Diversity in Wideband OFDM Systems: The Impact of Spatial Reuse and Frequency Selectivity (2008)

The goal of this paper is to establish which practical routing schemes for wireless networks are most suitable for wideband systems in the power-limited regime, which is, for example, a practically relevant mode of operation for the analysis of ultra-wideband (UWB) mesh networks. For this purpose, we study the tradeoff between energy efficiency and spectral efficiency (known as the power-bandwidth tradeoff) in a wideband linear multihop network in which transmissions employ orthogonal frequency-division multiplexing (OFDM) modulation and are affected by quasi-static, frequency-selective fading. Considering open-loop (fixed-rate) and closed-loop (rate-adaptive) multihop relaying techniques, we characterize the impact of routing with spatial reuse on the statistical properties of the end-to-end conditional mutual information (conditioned on the specific values of the channel fading parameters and therefore treated as a random variable) and on the energy and spectral efficiency measures of the wideband regime. Our analysis particularly deals with the convergence of these end-to-end performance measures in the case of large number of hops, i.e., the phenomenon first observed in [1] and named as "multihop diversity". Our results demonstrate the realizability of the multihop diversity advantages in the case of routing with spatial reuse for wideband OFDM systems under wireless channel effects such as path-loss and quasi-static frequency-selective multipath fading.
Automated Detection of Colorspace Via Convolutional Neural Network (2018)

Prior to the advent of ITU-R Recommendation BT.709 the overwhelming majority of compressed digital video and imagery used the colorspace conversion matrix specified in ITU-R Recommendation BT.601. The introduction of high-definition video formats led to the adoption of Rec. BT.709 for use in colorspace conversion by new systems, and this resulted in confusion in the industry. Specifically, video decoders may not be able to determine the correct matrix to use for converting from the luma/chroma representation used for coding, to the Red-Green-Blue representation needed for display. This confusion has led to a situation where some viewers of decompressed video streams experience subtle, but noticeable, errors in coloration. We have successfully developed and trained a deep convolutional neural network to address this heretofore unsolved problem. We obtained outstanding accuracy on ImageNet data, and on YouTube video frames, and our work can be expected to lead to more accurate color rendering delivered to users of digital imaging and video systems.
On the Performance of TCP in Reconfigurable Data Center Networks (2022)

Today’s data centers are hosting various applications under the same roof. The diversity among deployed applications leads to a complex traffic mix in Data Center Networks (DCNs). Reconfigurable Data Center Networks (RD-CNs) have been designed to fulfill the demanding requirements of ever-changing data center traffic. However, they pose new challenges for network traffic engineering, e.g., interference between reconfigurations and congestion control (CC). This raises a fundamental research problem: can the current transport layer protocols handle frequent network updates?; This paper focuses on the Transmission Control Protocol (TCP) and presents a measurement study of TCP variants in RDCNs. The quantitative analysis of the measurements shows that migrated flows suffer from frequent reconfigurations. The effect of reconfigurations on the cost, e.g. increased Flow Completion Time (FCT), depending on the traffic mix is modeled with Machine Learning (ML) methods. The availability of such a model will provide insights into the relationship between the reconfiguration settings and the FCT. Our model explains 88% of the variance in the FCT increase under different reconfiguration settings.
Determination of A.C. Conductivity of Nano-Composite Perovskite Ba&lt;sub&gt;(1- x - y)&lt;/sub&gt;Sr&lt;sub&gt;(x)&lt;/sub&gt;TiFe&lt;sub&gt;(y)&lt;/sub&gt;O&lt;sub&gt;3&lt;/sub&gt; Prepared by the Sol-Gel Technique (2012)

Nano-composite, perovskite Ba(1- x - y)Sr(x)TiFe(y)O3, denoted as (BSTFe) in powder form was derived via sol-gel (SG) method followed by sintering at fixed temperature 750℃ for one hour. The chemical composition, morphology and structure of the powder samples were investigated by using X-ray diffraction (XRD), transmission electron microscope (TEM) and scanning electron microscope (SEM). The XRD characterization indicates formation of a cubic crystalline phase in the pure BST. A well defined perovskite phase with nano-crystallite sizes equal to about 34 nm was achieved from XRD for B10ST3F sample, while TEM study confirmed the obtained XRD results giving the following crystallite size value about 33.75 nm for the same sample. The dielectric A.C. conductivity was evaluated as a function of temperature and frequency ranging from 42 Hz up to 1 MHz.
Figures S1-S18 from Circulating Tumor DNA Genomics Correlate with Resistance to Abiraterone and Enzalutamide in Prostate Cancer (2023)

&lt;p&gt;Supplementary Figures S1 - S18&lt;/p&gt;
Laser Flash and Dual Wavelength Photolysis of 3,4-Diaza-2,2-dimethoxy-1-oxa[4.5]spirooct-3-ene. Migration of Hydrogen and Carbon in Cyclobutylidene and in the Excited State of Its Precursor (1997)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTLaser Flash and Dual Wavelength Photolysis of 3,4-Diaza-2,2-dimethoxy-1-oxa[4.5]spirooct-3-ene. Migration of Hydrogen and Carbon in Cyclobutylidene and in the Excited State of Its PrecursorJohn Paul Pezacki, David L. Pole, John Warkentin, Tongqian Chen, Francis Ford, John P. Toscano, Jennifer Fell, and Matthew S. PlatzView Author Information Department of Chemistry, McMaster University 1080 Main Street West Hamilton, Ontario, Canada L8S4M1 Department of Chemistry, The Ohio State University 120 West 18th Avenue, Columbus, Ohio 43210 Cite this: J. Am. Chem. Soc. 1997, 119, 13, 3191–3192Publication Date (Web):April 2, 1997Publication History Received10 June 1996Published online2 April 1997Published inissue 1 April 1997https://doi.org/10.1021/ja961933rCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views304Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (112 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Carbene compounds,Excited states,Genetics,Photodissociation,Solvents Get e-Alerts
Abstract A08: Genetic drug resistance screen identifies LZTR1 as regulator of RAS ubiquitination and signaling (2020)

Abstract Small-molecule tyrosine kinase inhibitor (TKI)-based treatment of chronic myeloid leukemia (CML), directed by the presence of the Philadelphia chromosome (Ph+) encoded BCR-ABL tyrosine kinase, is a paradigm of targeted cancer therapy. However, the development of TKI resistance limits the long-term success of these therapeutics. We used a genetic screening approach in the near-haploid CML cell line KBM-7 to identify six genes whose individual loss of function led to TKI drug resistance. We investigated in detail the role of the leucine zipper-like transcription regulator 1 (LZTR1) gene, as it was mechanistically enigmatic despite its involvement in many human developmental and oncologic diseases including glioblastoma, schwannomatosis and Noonan syndrome. We found that LZTR1 inactivation led to enhanced MAPK pathway activity and reduced TKI sensitivity of CML cells in a RAS-dependent way. LZTR1 missense mutations identified in human diseases failed to revert the loss-of-function phenotype. Knockdown of the LZTR1 orthologue CG3711 in Drosophila led to an increase in ectopic wing vein formation that could be rescued by impairment of RAS gene function, confirming the epistatic relationship and suggesting an evolutionary conserved role for LZTR1 in RAS regulation. Endogenous LZTR1 protein associated with the four main RAS isoforms KRAS4A, KRAS4B, NRAS and HRAS in proximity biotinylation proteomic and immunoprecipitation experiments in a manner that for KRAS required farnesylation and palmitoylation. Ectopic expression of LZTR1 along with all four RAS proteins led to their ubiquitination, compatible with the proposed role of LZTR1 as a cullin (CUL)-3 E3 ligase adaptor. Loss of LZTR1 led to reduced ubiquitination of endogenous KRAS and its increased abundance as well as enhanced localization at the plasma membrane. Together with the work on the role of LZTR1 in diseases driven by the dysregulation of RAS ubiquitination and signaling (Steklov, Pandolfi, Baietti et al., Anna Sablina lab, KU Leuven; see separate abstract), we propose that LZTR1 acts as a conserved regulator of RAS ubiquitination and MAPK pathway activation, providing a mechanistic explanation to its genetic involvement across a variety of human pathologies. Citation Format: Johannes W. Bigenzahn, Giovanna M. Collu, Felix Kartnig, Melanie Pieraks, Gregory I. Vladimer, Leonhard X. Heinz, Vitaly Sedlyarov, Fiorella Schischlik, Astrid Fauster, Manuele Rebsamen, Katja Parapatics, Vincent A. Blomen, André C. Müller, Georg E. Winter, Robert Kralovics, Thijn R. Brummelkamp, Marek Mlodzik, Giulio Superti-Furga. Genetic drug resistance screen identifies LZTR1 as regulator of RAS ubiquitination and signaling [abstract]. In: Proceedings of the AACR Special Conference on Targeting RAS-Driven Cancers; 2018 Dec 9-12; San Diego, CA. Philadelphia (PA): AACR; Mol Cancer Res 2020;18(5_Suppl):Abstract nr A08.
Advanced CD-SEM metrology for pattern roughness and local placement of lamellar DSA (2014)

Directed self-assembly (DSA) applying chemical epitaxy is one of the promising lithographic solutions for next generation semiconductor device manufacturing. We introduced Fingerprint Edge Roughness (FER) as an index to evaluate edge roughness of non-guided lamella finger print pattern, and found its correlation with the Line Edge Roughness (LER) of the lines assembled on the chemical guiding patterns. In this work, we have evaluated both FER and LER at each process steps of the LiNe DSA flow utilizing PS-b-PMMA block copolymers (BCP) assembled on chemical template wafers fabricated with Focus Exposure Matrix (FEM). As a result, we found the followings. (1) Line widths and space distances of the DSA patterns slightly differ to each other depending on their relative position against the chemical guide patterns. Appropriate condition that all lines are in the same dimensions exists, but the condition is not always same for the spaces. (2) LER and LWR (Line Width Roughness) of DSA patterns neither depend on width nor LER of the guide patterns. (3) LWR of DSA patterns are proportional to the width roughness of fingerprint pattern. (4) FER is influenced not only by the BCP formulation, but also by its film thickness. We introduced new methods to optimize the BCP formulation and process conditions by using FER measurement and local CD valuation measurement. <br/> <br/> Publisher’s Note: This paper, originally published on 2 April 2014, was replaced with a corrected/revised version on 14 May 2014. If you downloaded the original PDF but are unable to access the revision, please contact SPIE Digital Library Customer Service for assistance.
Polymeric Sensor Materials: Toward an Alliance of Combinatorial and Rational Design Tools? (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Phase Transition and Microstructural Changes of Sol–Gel Derived ZrO2/Si Films by Thermal Annealing: Possible Stability of Tetragonal Phase without Transition to Monoclinic Phase (2012)

Stabilization of high-temperature phases such as tetragonal (t-) or cubic phases has been a pivotal issue for technological applications of polymorphic ZrO2. In this work, we fabricated ZrO2/Si films using a sol–gel deposition route and investigated the phase transformation, microstructural evolution, surface morphological changes, and interfacial chemical structures by thermal annealing. The ZrO2 precursor solution was prepared using a zirconium acetylacetonate, coated, dried on Si substrates, and finally annealed at 300–950 °C in ambient air. The sol–gel-derived ZrO2 layer crystallized into the t-phase as the annealing temperature increased. Despite high-temperature annealing, the t-phase was stabilized without a noticeable transition to the monoclinic phase, probably because of the relatively low film thickness (∼15 nm), enlarged surface/interface area due to thermal grooving, and strain effects. The probable t(112) orientation was developed after annealing at ≥800 °C, which could be related to minimization of the sum of the surface, interface, and strain energies. High-temperature thermal annealing resulted in the contraction of the ZrO2 layer as a result of the pyrolysis of the remnant organics, surface roughening by thermal grooving, and thickening of the amorphous interface layer (predominantly SiOx) between the ZrO2 and Si.
Uncalibrated visual servoing for intuitive human guidance of robots (2012)

We propose a novel implementation of visual servoing whereby a human operator can guide a robot relative to the coordinate frame of an eye-in-hand camera. Among other applications, this can allow the operator to work in the image space of the eye-in-hand camera. This is achieved using a gamepad, a time-of-flight camera (an active sensor that creates depth data), and recursive least-squares update with Gauss-Newton control. Contributions of this paper include the use of a person to cause the control action in a visual-servoing system, and the introduction of uncalibrated position-based visual servoing. The system's efficacy is evaluated via trials involving human operators in different scenarios.
Novel Polar Liquid Crystals with Very Low Birefringence Based ontrans-1,3-Dioxane Building Blocks (1998)

Liquid crystals with one or more trans-1,3-dioxane building blocks (see Figure) combine high dielectric anisotropy with low birefringence and favorable mesogenic and viscoelastic properties. A new, building-block-oriented synthetic strategy is described that offers convenient access to trans-1,3-dioxane–based core structures with various alkyl or alkenyl side chains or with a difluorovinyloxy(methyl) group as a polar end group.
The Biological Sciences Section Program at the 60th Annual Meeting of The Gerontological Society of America (2008)

In this era of genomics and other exciting technical advances, research on the biology of aging is undergoing a renaissance. This report summarizes 10 cutting-edge areas of research covered in symposia that spanned such topics as stem cells, novel vaccine strategies, nutritional sensing, new concepts of Parkinson's disease, high throughput screening for aging interventions, manipulating telomerase in cancer and immunodeficiency, synergy between aging and HIV disease, and epigenetic influences on aging. Novel animal models, including those showing no evidence of aging, as well as ethical and political implications of embryonic stem cells and alternative medicine are also discussed.
Modulation of Allergic Airway Inflammation by the Oral Pathogen Porphyromonas gingivalis (2010)

Accumulating evidence suggests that bacteria associated with periodontal disease may exert systemic immunomodulatory effects. Although the improvement in oral hygiene practices in recent decades correlates with the increased incidence of asthma in developed nations, it is not known whether diseases of the respiratory system might be influenced by the presence of oral pathogens. The present study sought to determine whether subcutaneous infection with the anaerobic oral pathogen Porphyromonas gingivalis exerts a regulatory effect on allergic airway inflammation. BALB/c mice sensitized and subsequently challenged with ovalbumin exhibited airway hyperresponsiveness to methacholine aerosol and increased airway inflammatory cell influx and Th2 cytokine (interleukin-4 [IL-4], IL-5, and IL-13) content relative to those in nonallergic controls. Airway inflammatory cell and cytokine contents were significantly reduced by establishment of a subcutaneous infection with P. gingivalis prior to allergen sensitization, whereas serum levels of ovalbumin-specific IgE and airway responsiveness were not altered. Conversely, subcutaneous infection initiated after allergen sensitization did not alter inflammatory end points but did reduce airway responsiveness in spite of increased serum IgE levels. These data provide the first direct evidence of a regulatory effect of an oral pathogen on allergic airway inflammation and responsiveness. Furthermore, a temporal importance of the establishment of infection relative to allergen sensitization is demonstrated for allergic outcomes.