gebhart/patrepeval huggingface dataset:
Verification of reliability of numerical analysis by comparison with actual crash impact test of rotorcraft fuel tank (2019)

The general function of a fuel tank is to store fuel. However, the structural soundness of a fuel has a great influence on the survival of the crew in an emergency situation such as an aircraft crash. For this reason, countries with advanced aviation technology have developed crashworthy fuel tank for decades. The crashworthiness performance of fuel tank is demonstrated by the crash impact test, which has high risk of failure due to the high impact loads, so much effort has been made to minimize the possibility of failure in the actual test. Numerical analysis performed before the actual test is a part of such efforts. However, for the results of numerical analysis to be reflected in the design, a certain level of reliability of the numerical analysis is required. In this study, the results of a numerical analysis and actual crash impact test data were compared to verify the reliability of the numerical analysis. Crash analysis software (LS-DYNA) was used and the arbitrary Lagrangian–Eulerian (ALE) technique was applied as the analysis method. To obtain actual test data, strain gages were installed on the metal fittings of the fuel tank and linked to the data acquisition equipment. As a result of the numerical analysis, strain and stress of the fuel tank fittings were calculated. And, the reliability of the numerical analysis was enhanced by assessing the error between the strain measurement of the upper fittings obtained from an actual fuel tank test and the strain calculated from the numerical analysis.
Interactive, topic-based visual text summarization and analysis (2009)

We are building an interactive, visual text analysis tool that aids users in analyzing a large collection of text. Unlike existing work in text analysis, which focuses either on developing sophisticated text analytic techniques or inventing novel visualization metaphors, ours is tightly integrating state-of-the-art text analytics with interactive visualization to maximize the value of both. In this paper, we focus on describing our work from two aspects. First, we present the design and development of a time-based, visual text summary that effectively conveys complex text summarization results produced by the Latent Dirichlet Allocation (LDA) model. Second, we describe a set of rich interaction tools that allow users to work with a created visual text summary to further interpret the summarization results in context and examine the text collection from multiple perspectives. As a result, our work offers two unique contributions. First, we provide an effective visual metaphor that transforms complex and even imperfect text summarization results into a comprehensible visual summary of texts. Second, we offer users a set of flexible visual interaction tools as the alternatives to compensate for the deficiencies of current text summarization techniques. We have applied our work to a number of text corpora and our evaluation shows the promise of the work, especially in support of complex text analyses.
Cisco Vendor-Specific RADIUS Attributes for the Delivery of Keying Material (2011)

This document defines a set of vendor-specific RADIUS Attributes designed to allow both the secure transmission of cryptographic keying material and strong authentication of any RADIUS message.These attributes have been allocated from the Cisco vendor-specific space and have been implemented by multiple vendors.
Marine Oomycetes (<i>Halophytophthora</i> and <i>Salispina</i>): A Potential Source of Fatty Acids with Cytotoxic Activity Against Breast Adenocarcinoma Cells (MCF7) (2019)

Marine oomycetes are ubiquitous, fungus-like eukaryotes known to produce fatty acids with potential anticancer activity. The long chain omega-3 and omega-6 fatty acids are currently popular and considered as safe when used as nutraceuticals in cancer treatment. In this study, crude fatty acids from three marine oomycetes, Halophytophthora spp. (T12GP1 and T12YBP2) and Salispina hoi (USTCMS 1611), were explored for their cytotoxic and apoptotic potentials against human breast adenocarcinoma cells (MCF7) and normal human dermal fibroblasts (HDFn). Extracts from mycelia mats consisted of diverse saturated, monounsaturated, and polyunsaturated fatty acids such as linoleic, α-linolenic, γ-linolenic, eicosatrienoic and eicosapentaenoic acids. The crude fatty acids from all three oomycetes in in vitro assays for cytotoxicity showed no toxicity (30% toxicity values) on HDFn cells. On MCF7 cells, however, IC<sub>50</sub> values of 23.44, 15.63, and 26.15 µg/mL were obtained with extracts from Halophytophthora T12GP1 and T12YBP2 and S. hoi, respectively. Treated MCF7 cells exhibited deformed cell membrane in MTT assay and also aggregation of DNA and disruption of nuclear membrane aggregation in nuclear staining; further, green signals indicative of apoptosis was recorded in caspase 3/7 assay.
Integrative Advances for OCT-Guided Ophthalmic Surgery and Intraoperative OCT (2015)

Microscope-integrated intraoperative OCT (iOCT) allows live cross-sectional imaging concurrent with ophthalmic surgery and dynamic visualization of tissue-instrument interactions. However, limited volumetric data acquisition rates and three-dimensional rendering and display remain critical barriers to iOCT-guided surgical maneuvers. We present a microscope-integrated iOCT system with heads-up display (HUD) and novel semi-transparent ophthalmic surgical instruments. Cross-sectional iOCT imaging of surgical maneuvers using real-time HUD feedback and novel instrumentation is used to demonstrate the utility of real-time cross-sectional imaging for surgical guidance.
Ultra-thin gate oxide yield and reliability (2002)

In this paper we demonstrate that ultra-thin (3-6 nm) gate oxides with a very good thickness uniformity and a low defect density can be grown by thermal oxidation using a conventional furnace. A strong reduction of the low field MOS leakage current, related to oxide wearout, is observed for thinner oxides and correlates with a dramatic improvement of the TDDB characteristics. It is shown that the voltage scaling of future MOS devices with an oxide thickness less than 5 nm will be determined by the direct tunnel current through the oxide.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Re: Castration Resistance in Human Prostate Cancer is Conferred by a Frequently Occurring Androgen Receptor Splice Variant (2011)

No AccessJournal of UrologyInvestigative Urology1 Apr 2011Re: Castration Resistance in Human Prostate Cancer is Conferred by a Frequently Occurring Androgen Receptor Splice Variant Anthony AtalaM.D. Anthony AtalaAnthony Atala More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2010.12.023AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Re: Castration Resistance in Human Prostate Cancer is Conferred by a Frequently Occurring Androgen Receptor Splice Variant." The Journal of Urology, 185(4), p. 1532 © 2011 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 185Issue 4April 2011Page: 1532 Advertisement Copyright & Permissions© 2011 by American Urological Association Education and Research, Inc.MetricsAuthor Information Anthony Atala More articles by this author Expand All Advertisement PDF downloadLoading ...
Genetic Susceptibility Markers in Danish Patients with Type 1 (Insulin-Dependent) Diabetes-Evidence for Polygenecity in Man (1994)

Fifty-five Danish families with two offspring concordant for type 1 diabetes--identified through a nationwide population-based survey, and 57 "true sporadic" cases--matched with familial cases for age at onset, but with no IDDM-affected first-degree relatives and long disease duration, and 110 control subjects were typed for putative genetic susceptibility markers for type 1 diabetes identified from a pathogenetic model. The markers included MHC class I, II and III loci, the manganese superoxide dismutase (MnSOD) locus (chr. 6q), interleukin-1 beta (IL1B), the IL-1 receptor antagonist (IL1RN), and the IL-1 type 1 receptor (IL1RI) loci (each chr. 2q). No significant differences between familial and sporadic cases were found within the MHC region (including the following loci: HLA-DQ, -DR, heat shock protein (HSP) 70, tumour necrosis factor (TNF), HLA-B and -A). In both groups of patients 11% were negative for both DQA1*0301-DQB1*0302 and DQA1*0501-DQB1*0201 genotypes, and 7% of the type 1 diabetics had genotypes unable to encode a susceptibility DQ alpha beta heterodimer. Disease association was found for the IL1RN (p = 0.04) and for the IL1RI (p = 0.03). When comparing controls and only familial cases with type 1 diabetes for the IL1RN polymorphism a difference was observed (p = 0.003). For the IL1B RFLP a trend for difference was observed between familial cases and control subjects (p = 0.046), whereas no differences between sporadic cases and control subjects could be demonstrated neither at the IL1B nor at the IL1RN loci. A difference in the MnSOD pattern was observed between sporadic cases and controls (p = 0.04).
454 pyrosequencing and bioinformatics analysis of the lineage of the broad and potent gp41-directed antibody 10e8 (2012)

Results 37,669 IGHV3-15 heavy chain sequences and 91,951 IGLV3-19 light chain sequences were obtained and the distribution of these sequences analyzed by two key parameters – divergence from germline and sequence identity to 10e8. Grid-based clustering allowed for the selection of 61 heavy chain sequences and 48 light chain sequences. These were reconstituted with the appropriate 10e8 light or heavy chain partner, expressed and tested for MPER recognition. 12 heavy chain variants and 27 light chain variants were found to bind MPER, and several of the reconstituted antibodies neutralized a panel of HIV-1 isolates better than the original 10e8. Phylogenetic analyses identified clonally-related sequences, and at least three subgroups of 10e8-like heavy chains were observed. 10e8 light chains meanwhile also showed a few subgroups, though with less sequence variation.
Role of the nuclear envelope in the regulation of mRNA transport (1986)

Abstract The export of processed RNA molecules from the nucleus is an intricately regulated process, subject to various developmental and physiological controls. The structural and biochemical properties of the nuclear envelope that are involved in this process are described here.
Intravascular Magnetic Resonance Imaging of Aortic Atherosclerotic Plaque Composition (1997)

Magnetic resonance imaging (MRI) may be an excellent tool to define atherosclerotic plaque composition, but surface MRI (SMRI) suffers from a low signal-to-noise ratio and low resolution of arterial images. Intravascular MRI (IVMRI) represents a potential solution for acquiring high-quality in vivo images of atherosclerotic plaques. Isolated segments of 11 thoracic human aortas obtained at autopsy were imaged by IVMRI using an intravascular receiver catheter coil designed and built at our institution. Images obtained by IVMRI were compared with corresponding images obtained by SMRI and with histopathological aortic cross sections. The intensity of intimal thickness and plaque components was graded by IVMRI and histopathology using a score of 1 for mild, 2 for moderate, and 3 for severe intensity. IVMRI had an agreement of 75% with histopathology in fibrous cap grading (37.5% expected, kappa = 0.60, P < 0.001) and of 74% in necrotic core grading (39% expected, kappa = 0.57, P < 0.001). Intraplaque calcification was correctly graded by IVMRI in six of the eight plaques in which histopathology recognized calcium. The analysis of intimal thickness showed 80% agreement between IVMRI and histopathology (52% expected, kappa = 0.59, P < 0.001). IVMRI image features were similar to those of SMRI. In addition, IVMRI accurately determined atherosclerotic plaque size in comparison with histopathology and SMRI (slope = 1.25 cm2, r = 0.99, P < 0.001 for luminal area by IVMRI vs histopathology; slope = 0.97 cm2, r = 0.996, P < 0.001 for luminal area by IVMRI vs SMRI). IVMRI has the potential to provide important prognostic information in patients with atherosclerosis because of its ability to accurately assess both plaque composition and size.
Is service priority useful in networks? (1998)

A key question in the definition of new services for the Internet is whether to provide a single class of relaxed real-time service or multiple levels differentiated by their delay characteristics. In that context we pose the question: is service priority useful in networks? We argue that, contrary to some of our earlier work, to properly address this question one cannot just consider raw network-centric performance numbers, such as the delay distribution. Rather, one must incorporate two new elements into the analysis: the utility functions of the applications (how application performance depends on network service), and the adaptive nature of applications (how applications react to changing network service). This last point is especially crucial; modern Internet applications are designed to tolerate a wide range of network service quality, and they do so by adapting to the current network conditions. Most previous investigations of network performance have neglected to include this adaptive behavior.In this paper we present an analysis of service priority in the context of audio applications embodying these two elements: utility functions and adaptation. Our investigation is far from conclusive. The definitive answer to the question depends on many factors that are outside the scope of this paper and are, at present, unknowable, such as the burstiness of future Internet traffic and the relative offered loads of best-effort and real-time applications. Despite these shortcomings, our analysis illustrates this new approach to evaluating network design decisions, and sheds some light on the properties of adaptive applications.
Indexing compressed text (2005)

We design two compressed data structures for the full-text indexing problem that support efficient substring searches using roughly the space required for storing the text in compressed form.Our first compressed data structure retrieves the occ occurrences of a pattern P [1, p ] within a text T [1, n ] in O ( p + occ log 1+ε n ) time for any chosen ε, 0&lt;ε&lt;1. This data structure uses at most 5 n H k ( T ) + o ( n ) bits of storage, where H k ( T ) is the k th order empirical entropy of T . The space usage is Θ( n ) bits in the worst case and o ( n ) bits for compressible texts. This data structure exploits the relationship between suffix arrays and the Burrows--Wheeler Transform, and can be regarded as a compressed suffix array .Our second compressed data structure achieves O ( p + occ ) query time using O ( n H k ( T )log ε n ) + o ( n ) bits of storage for any chosen ε, 0&lt;ε&lt;1. Therefore, it provides optimal output-sensitive query time using o ( n log n ) bits in the worst case. This second data structure builds upon the first one and exploits the interplay between two compressors: the Burrows--Wheeler Transform and the LZ78 algorithm.
Integrated fiber optic incoherent broadband cavity enhanced absorption spectroscopy detector for near-IR absorption measurements of nanoliter samples (2012)

An integrated fiber-optic sensor is described that uses incoherent broadband cavity enhanced absorption spectroscopy for sensitive detection of aqueous samples in nanoliter volumes. Absorption was measured in a 100 µm gap between the ends of two short segments of multimode graded-index fiber that were integrated into a capillary using a precision machined V-grooved fixture that allowed for passive fiber alignment. The other ends of the fibers were coated with dielectric mirrors to form a 9.5 cm optical resonator. Light from a fiber-coupled superluminescent diode was directly coupled into one end of the cavity, and transmission was measured using a fiber-coupled silicon photodiode. Dilute aqueous solutions of near infrared dye were used to determine the minimum detectable absorption change of 2.4×10(-4) under experimental conditions in which pressure fluctuations limited performance. We also determined that the absolute minimum detectable absorption change would be 1.6×10(-5) for conditions of constant pressure in which absorption measurement is limited by electronic and optical noise. Tolerance requirements for alignment are also presented.
MRI-guided optical tomography: prospects and computation for a new imaging method (1995)

Living tissue scatters near-infrared light randomly, can this problem be overcome to make NIR optical tomography possible? If so, it could be more accurate and less damaging than other medical imaging techniques. Computational experiments using combined MRI-optical methods show promise.
Statusnotat - evaluering og følgeforskning: Indførelse af den ny fælles prøve i Fysik/kemi, biologi og geografi - prøvens betydning for undervisningens form og indhold (2018)

Rapporten opsummerer omfattende kvantitative og kvalitative undersøgelser af, hvorledes det gik med implementationen af den nye fælles prøve i naturfagene fysik/kemi, biologi og geografi ifm eksamen 2017 (første prøveår). Grundlæggende blev prøven gennemført på betryggende vis, men rapporten peger samtidig på en række forhold, som med fordel kan forbedres, både hvad angår den fællesfaglige undervisning og de organisatoriske rammer for denne.
Publisher’s Note: Sub-Shot-Noise Transmission Measurement Enabled by Active Feed-Forward of Heralded Single Photons [Phys. Rev. Applied 8, 014016 (2017)] (2017)

Received 5 October 2017DOI:https://doi.org/10.1103/PhysRevApplied.8.049902Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article’s title, journal citation, and DOI.© 2017 American Physical SocietyPhysics Subject Headings (PhySH)Research AreasOptical quantum information processingPhotonicsQuantum fluctuations & noiseQuantum measurementsQuantum metrologyQuantum opticsSingle photon sourcesAtomic, Molecular & Optical
Volumetric Imaging of Neural Activity employing an Overdrive Spatial Light Modulator (2018)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text R. Liu, N. Ball, J. Brockill, J. Zhuang, C. Whites, L. Kuan, R. Valenza, A. Steger, S. Nishiwaki, D. Sullivan, C. Slaughterbeck, C. Farrell, J. Lecoq, and P. Saggau, "Volumetric Imaging of Neural Activity employing an Overdrive Spatial Light Modulator," in Biophotonics Congress: Biomedical Optics Congress 2018 (Microscopy/Translational/Brain/OTS), OSA Technical Digest (Optica Publishing Group, 2018), paper BW2C.4. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
HLA–E gene polymorphism associated with susceptibility to kawasaki disease and formation of coronary artery aneurysms (2009)

Our results suggest that the HLA-E gene polymorphism may play a role in the pathogenesis of KD.
Component characterization and commissioning of a gamma-PET prototype detector system (2022)

Hybrid imaging systems, comprising PET and Compton camera modules, have recently gained in interest, due to their capability to simultaneously detect positron annihilation photons and γ-rays from single-photon emitting sources as also used in SPECT. A unique feature of such systems, however, is the capability to also be operated in a so called γ-PET mode. Here, specific β + - emitting radioisotopes (such as 44 Sc, 1 °C or 14 O) are used to detect triple-coincidences between two annihilation γ-rays (in PET imaging) and a third, prompt photon (in Compton imaging), that is emitted by the deexcitation of the decay’s daughter nucleus. Consequently, an intersection between the line-of-response (LOR) and the Compton cone can be determined, which (in principle) allows to localize the photons’ emission vertices on a single decay basis. In practice, however, a few tens of events are required to localize a point source, which still results in a considerable sensitivity improvement compared to conventional PET imaging. For a proof-of-principle study, we used a pixelated GAGG crystal array (16 × 16 crystals; 1.45 × 1.45 × 6 mm 3 crystal volume; 25 μm SPAD SiPMs as readout) as Compton camera scatterer and PET detectors, and a three-layered LYSO crystal array (1.2 × 1.2 × 6.66 mm 3 crystal volume; 50 μm SPAD SiPMs as readout) as Compton camera absorber. We characterized the individual detector components with regard to their energy resolution and the capability to identify the various scintillator array’s individual crystals. Our first γ-PET prototype was tested in PET-only and Compton-only imaging mode, in which spatial resolutions of 3.2–3.5 mm FWHM (PET-only mode) and 14.4–19.3 mm FWHM (Compton-only mode at 1,274 keV) were achieved, respectively, using a 22 Na point source and 10 iterations of an ML-EM reconstruction algorithm. By using triple-coincidences in a γ-PET mode (event-wise intersection of the LOR and the Compton cone), we could demonstrate the capability of the prototype to perform a full 3D point source reconstruction using only 77 events.
Continuity and reliability assessment of a scalable 3×50μm and 2×40μm via-middle TSV module (2016)

An advanced TSV metallization scheme, featuring a high conformal ALD oxide liner, a thermal ALD WN barrier, an electroless NiB platable seed and a high throughput copper ECD filling is presented. Because of the high conformality of the WN barrier and NiB seed, very thin layers can be deposited, reducing the manufacturing cost significantly, while still guaranteeing continuous barrier/seed layers all along the TSV sidewall to the bottom of the TSV. 3 × 50μm via-middle wafers, processed with this metallization scheme, are further processed through the thinning module, by using temporary bonded carriers, the backside passivation module and a copper RDL module by using a semi-additive process. The TSV resistance is measured between the 5μm thick RDL copper layer at the back side and the METPASS aluminum layer at the wafer front side. Low spread and high yield is obtained on the resistance data distribution of both single kelvin and daisy chain structures. The same metallization scheme is successfully scaled to a 2μm diameter and 40μm deep via-middle module. The conformal deposition of the barrier and the seed layer enables further scaling down to aspect ratio 20:1 through silicon via's with 5μm pitch, still ensuring the void-free bottom up copper fill by electroplating. The integrity of the liner/barrier system against Cu diffusion from TSV to silicon has been verified using the established controlled I-V method. Field acceleration factors, extracted in both copper-confined and copper-driven regime, indicate good TDDB reliability of this advanced 2 × 40μm TSV middle module.
The Link between Fusobacteria and Colon Cancer: a Fulminant Example and Review of the Evidence (2020)

Systemic infections due to <i>Fusobacterium</i> may originate in the tonsillar/internal jugular veins or from the abdomen. We encountered a patient who presented with bacteremia, fulminant septic shock, and extensive soft tissue pyogenic infection due to <i>Fusobacterium necrophorum</i>. In addition, there was widespread metastatic colon cancer with the unique finding of pre-mortem co-localization of <i>F. necrophorum</i> and cancer cells at a site distant from the colon. We reviewed the literature of the association of <i>F. necrophorum</i> and colon cancer, and discuss the evidence of how each of these 2 distinct entities may mutually augment the development or progression of the other.