gebhart/patrepeval huggingface dataset:
Performance of 70 nm strained-silicon CMOS devices (2004)

An 86% electron mobility improvement and over 20% I/sub dn-sat/ enhancement were demonstrated for a 70 nm strained-Si CMOS process fabricated on SiGe virtual substrates. Compared to a bulk-Si CMOS process, the strained-Si process delivered 95% higher inverter peak-current and a 2.2 ps reduction in ring oscillator delay for the same drive current. Strained and bulk CMOS featured equivalent gate leakage through a 16 /spl Aring/ nitrided oxide, which remained the dominant leakage source despite dislocation-induced junction leakage observed on strained-Si wafers. Self-heating of strained-Si CMOS due to the low thermal conductivity SiGe virtual substrate reduces I/sub dn-sat/ by 7% during DC operation.
Compensating changes in speaker position for improved voice-based human-robot communication (2015)

Acoustic perturbation due to reverberation and the changes in speaker position are detrimental to seamless human-robot speech-based communication. These cause a mismatch between the speech features at runtime condition and the acoustic model (training condition). Then the degradation of the Automatic Speech Recognition (ASR) and the Spoken Language Understanding (SLU) performances is imminent. As a consequence, the robot fails to understand the spoken commands which will negatively impact interaction experience. In this paper, we propose a framework to improving speech-based human-robot communication in various reverberant environments. The framework is based on robust robot audition that addresses the mismatch problem, striking a balance between technology and the limitations in a real robot setting. Our method improves both ASR and SLU performances. Moreover, the proposed framework has the ability to evolve in minimizing mismatch without human supervision. We experiment with data collected in real environment conditions.
Isothermal vapor-liquid equilibrium of binary mixtures containing morpholine (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsothermal vapor-liquid equilibrium of binary mixtures containing morpholineHuey S. Wu, William E. Locke III, and Stanley I. SandlerCite this: J. Chem. Eng. Data 1991, 36, 1, 127–130Publication Date (Print):January 1, 1991Publication History Published online1 May 2002Published inissue 1 January 1991https://pubs.acs.org/doi/10.1021/je00001a037https://doi.org/10.1021/je00001a037research-articleACS PublicationsRequest reuse permissionsArticle Views248Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evaluation of a Context-Aware Mobile Peer-to-Peer Navigation Application (2007)

In mobile networking, the use of context information in a versatile manner is emerging. Context information, which characterizes the situation of an entity, provides ease of use in mobile devices with limited input and output capabilities. A mobile peer-to-peer navigation application uses context information to verify this statement. It acts as a graphical user interface for group-based context-aware communication and as an enabler of inter-application cooperation. It uses an intelligent application platform for distributing context information. The analytical results consist of quantitative evaluation, involving functional testing and delay analysis, and a qualitative evaluation, involving user testing. The concepts of group-based context distribution and inter- application cooperation were found functional and useful.
Libra (2007)

If the operating system could be specialized for every application, many applications would run faster. For example, Java virtual machines (JVMs) provide their own threading model and memory protection, so general-purpose operating system implementations of these abstractions are redundant. However, traditional means of transforming existing systems into specialized systems are difficult to adopt because they require replacing the entire operating system. This paper describes Libra, an execution environment specialized for IBM's J9 JVM. Libra does not replace the entire operating system. Instead, Libra and J9 form a single statically-linked image that runs in a hypervisor partition. Libra provides the services necessary to achieve good performance for the Java workloads of interest but relies on an instance of Linux in another hypervisor partition to provide a networking stack, a filesystem, and other services. The expense of remote calls is offset by the fact that Libra's services can be customized for a particular workload; for example, on the Nutch search engine, we show that two simple customizations improve application throughput by a factor of 2.7.
Quantifying an acceptable open-circuit corrosion current for aluminum–air batteries (2021)

By deriving a corrosion model, we show that anodes in most aluminum–air batteries corrode too quickly for commercial applications.
Polymorphisms of 3-hydroxy-3-methylglutaryl Coenzyme A Reductase Gene Are Not Associated with the Osteonecrosis of Femoral Head in Korean (2008)

대퇴골두무혈성괴사증은 다원적인 질병으로 특정 집단의 경우 더 많은 위험성을 내포하고 있다. 특히 스테로이드의 과용과 알코올 남용 등으로 인한 지질대사의 변화는 골괴사증의 주요 원인 중 하나이다. 본 연구는 골괴사 환자와 대조군 사이에서 HMG-CoA reductase 유전자의 다형성과 질환발생과의 연관성에 대해 알아보았다. 24명의 한국인을 대상으로 HMG-CoA reductase 유전자를 시퀀싱하여 5곳의 유전자 다형성을 확인하였다. 349명의 남성 환자와 300명의 남성 대조군을 대상으로 네 곳(-6933C>T, -6045T>G, +12673G>A, +18128C>T)의 유전자다형성의 빈도를 비교하였다. 그 결과 HMG-CoA reductase 유전자의 다형성과 질환발생 및 혈장 지질농도와는 어떠한 상관관계도 보이지 않았다. Osteonecrosis of the femoral head (ONFH) is a multifactorial disease and certain individuals are more at risk or may be predisposed to it. An altered lipid metabolism is one of the major risk factors for osteonecrosis, especially corticosteroid therapy and alcoholism. 3-hydroxy-3-methylglutaryl coenzyme A. (HMG-CoA) reductase inhibitors, stalin used as lipid-clearing agent, have been known to decrease the risk of osteonecrosis in patients receiving steroids and affect coagulation and fibrinolysis. Therefore we evaluated the association of HMG-CoA reductase gene polymorphisms and haplotypes between osteonecrosis patients and normal controls. We directly sequenced the HMG-CoA reductase gene in 24 Korean individuals, and identified five sequence variants. Four SNPs (-6933C>T, -6045T>G, +12673G>A, and +18128C>T) were selected and genotyped in 349 male ONFH patients and 300 male control subjects. The genotypes, allele frequencies, and haplotypes of the polymorphisms in the total patients as well as in the subgroup by etiology were not significantly different from those in the control group. In addition, no significant differences between each genotype of the polymorphisms and plasma lipid level could be found in the control group. These results suggest that the polymorphisms and haplotypes of HMG-CoA reductase gene are unlikely to be associated with a susceptibility to ONFH.
7-Motion discrimination technique for forearms using real-time EMG signals (2012)

The objective of this study is to develop a method of discriminating real-time motion from electromyogram (EMG) signals. We previously proposed a motion discrimination method. That could discriminate five motions (hand opening, hand closing, hand chucking, wrist extension, and wrist flexion) at a rate of above 90 percent from four channel EMG signals in real time (the discrimination processing time was less than 300 ms). This method prevented elbow motions from interfering with hand motion discrimination, but it could only discriminate five motions, as opposed to a method using neural networks that can discriminate more than six. Here, we propose a real-time 7-motion discrimination method using a hyper-sphere model. The seven motions are hand opening, hand closing, hand chucking, wrist extension, wrist flexion, ulnar flexion, and radial flexion. The proposed model can learn EMG signals in real-time. Experimental results showed that the discrimination accuracy of this method was above 90 percent. Moreover, elbow motions did not interfere with the hand motion discrimination. The discrimination processing time was less than 300 ms.
Efficiency improvement of grid-tied inverters at low input power using pulse skipping control strategy (2010)

Pulse skipping control strategy is applied to improve efficiency of grid-tied inverter at light load. To maximize the efficiency of pulse skipping operation mode, three key parameters are identified and can be optimized based on a loss model, which is developed to find the maximal efficiency points using three-dimension searching technique. To reduce the potential of pulsating on the power grid, the synchronization of the power pulse to the grid is addressed by varying the DC bus voltage window, namely varying the upper and lower DC voltage limits. A 200 W prototype is setup to verify the proposed strategy. The experimental results show that the proposed strategy greatly improves the efficiency at light load and match the simulation results fairly well, thus verifying the validity of the proposed optimization method for pulse skipping.
Optical Triggers of Protein Folding (1996)

In our report about the electron-transfer&#13;\n(ET)-initiated folding of ferrocytochrome c&#13;\n(cyt c^(II)) (1), we noted rapid changes&#13;\nin the visible absorption spectrum corresponding to a process with a time constant of&#13;\n~40 µs. We indicated that this observation&#13;\nwas consistent with studies of cyt c^(ll) folding&#13;\ninitiated by CO dissociation where the fast&#13;\ndynamics were attributed to changes in heme&#13;\nligation (2). We also suggested that these&#13;\ndynamics might correspond to the collapse of&#13;\nthe protein into a compact denatured state, as&#13;\nhas been proposed for apomyoglobinon the&#13;\nbasis of laser-temperature-jump measurements&#13;\n(3). Our transient absorption data could not&#13;\ndistinguish between the two possibilities, and&#13;\nthese fast folding dynamics were a relatively&#13;\nminor component of the study described in&#13;\nour report. Chan et al., with the use of tryptophan (Trp) fluorescence as a probe, found&#13;\nno significant collapse of the protein on the&#13;\nsubmillisecond time scale following dissociation&#13;\nof CO from unfolded cyt c^(II). Clearly,&#13;\nmultiples pectroscopic probes must be employed&#13;\nto study protein folding; accordingly,&#13;\nwe are currently developing time-resolved Trp&#13;\nfluorescence as a probe for ET-initiated folding&#13;\nof cyt c^(II).
The Effect of an Orthopedic Trauma Room on After-Hours Surgery at a Level One Trauma Center (2008)

It is possible to dramatically decrease the occurrence of after-hours orthopedic surgery in a level-one trauma center through the use of a dedicated room for unscheduled orthopedic trauma cases. Benefits include less frequent activation of after-hours operating room resources, fewer disruptions to the OR schedule and office hours, and more frequent fracture care by orthopedic traumatologists. The impact of a longer delay between admission and surgical treatment and more frequent transfer of care between surgeons deserves further evaluation.
Data from Vandetanib, Designed to Inhibit VEGFR2 and EGFR Signaling, Had No Clinical Activity as Monotherapy for Recurrent Ovarian Cancer and No Detectable Modulation of VEGFR2 (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; To evaluate clinical activity and target modulation of vandetanib in women with recurrent ovarian cancer.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; A phase II trial of orally administered vandetanib 300 mg daily was designed to include analyses of target inhibition through paired biopsies and dynamic imaging. Core 18-gauge needle biopsies and dynamic contrast-enhanced magnetic resonance imaging were obtained before initiation of therapy and 6 weeks into therapy. Biopsy samples were subjected to reverse-phase protein lysate array endpoint analysis. Cytokine concentrations were measured by enzyme-linked immunosorbent assay in serially collected plasma samples.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; Twelve patients entered the study, and accrual was terminated in the first stage because of lack of response or disease stabilization beyond 6 months. Adverse events included rash, diarrhea, and prolonged QT interval corrected for heart rate, but not hypertension. Exploratory analyses showed that epidermal growth factor receptor (EGFR) phosphorylation was reduced in the eight paired biopsy sets obtained; vascular endothelial growth factor (VEGF) receptor-2 phosphorylation was not consistently affected nor were dynamic contrast-enhanced MRI permeability and flow parameters. Serial plasma VEGF concentrations were variable and did not significantly change in the 11 patients assessed.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Vandetanib 300 mg daily monotherapy had no significant clinical benefit in this disease setting. Proteomic analysis of paired biopsies detected both phosphorylated-EGFR and phosphorylated-VEGF receptor-2 in ovarian tumor tissue, but only phosphorylated-EGFR was measurably inhibited by vandetanib. Clin Cancer Res; 16(2); 664–72&lt;/p&gt;&lt;/div&gt;
Rescue of a transgenic mouse line by transplantation of a frozen-thawed ovary obtained postmortem. (2001)

During the course of breeding valuable mutant or transgenic mice, deaths sometimes occur due to sudden-onset disease or accident. We previously showed that mice can be rescued by transplantation of ovaries taken up to 2 h after death from dead mice remaining at conditions of constant temperature (22 +/- 2 degrees C) and humidity (55% +/- 5%). To extend the flexibility of transplantation, we assessed whether it is possible to cryopreserve ovaries taken from dead mice within 2 h after death. Fertile transgenic mice used as donors were euthanized by cervical dislocation and left for 2 h after death. The cryopreservation was based on Sztein's method with a controlled-rate freezer or on Rall and Fahy's method without a controlled-rate freezer. The recipient mice were nontransgenic littermates of the donor mice, and after transplantation of the frozen-thawed ovaries, they were mated with proven-fertile males. Polymerase chain reaction (PCR) analysis confirmed that the progeny carried the transgene. We show here that by using both of the described methods, it is possible to cryopreserve the ovaries taken from dead mice within 2 h after death and that the mice into which the cryopreserved ovaries are transplanted are fertile.
Experimental Study on Ray Based Spatio-Temporal Channel Characteristics in Indoor Environment (2015)

This paper describes characteristics of direct and scattered waves that are extracted from measurement channel data obtained using a 3.35GHz vector channel sounder in an indoor environment. For the scattered waves, a ray number, n, is assigned to each ray in order of the received levels and the relationship between n and the characteristics of each ray such as the received level, delay and azimuth angle of arrival (AOA) are investigated. The distribution of the received level for each n, which is normalized to the received level that is calculated based on free space at each measurement point and includes the received level of all measurement points, is a log normal distribution. Moreover, the median received level of each n of the scattered waves is approximated with two different gradient linear lines as a function of n. Furthermore, the azimuth AOA for the ray of scattered waves whose received level is relatively high is biased in the base station antenna direction and the distribution of the azimuth AOA becomes uniform with a decrease in the received ray level. Finally, a spatio-temporal channel model is proposed based on the above mentioned analysis.
Next-Generation Broadband Access Networks (2009)

This tutorial first describes the current evolution in time-division multiplexed (TDM) passive optical networks (PON) from today’s commercially available 2.5-Gb/s TDM PONs to the newly standardized 10-Gb/s TDM PONs. The second part of the tutorial focuses on the diverse set of PON technologies under consideration for standardization beyond 10 Gb/s.
Abstract #4630: EZN-3920, an LNA antisense oligonucleotide RNA antagonist, down modulates HER3 expression and PI3K/Akt signaling pathway and enhances antiproliferative effect of Gefitinib in tumor cells (2009)

Introduction: The ErbB family consists of four tyrosine kinase receptors designated as ErbB1 (EGFR), HER2, HER3 and HER4. Inhibition of HER3 is likely to have antitumor effects since HER3 (1) heterodimerizes with HER2 and EGFR, (2) is a key link to the PI3K pro-survival signaling pathway, and (3) is activated in cells resistant to EGFR or HER2 targeting therapeutics. This study aimed at evaluating the activities of EZN3920, an HER3 locked nucleic acid (LNA) antisense oligonucleotide (ON), in various tumor cells. The regulation on downstream PI3K/Akt pathway and combination with EGFR inhibitor were also explored. Experimental Procedures: In vitro: the target knockdown, phospho-Akt inhibition, growth inhibition, apoptosis induction effects of EZN-3920 (Santaris Pharma) were evaluated by qRT-PCR, western blot analysis, MTS assay, caspase3/7 activity assay, respectively, in 14 cancer (prostate, liver, lung, colon, stomach, ovarian, breast, and epidermoid) cell lines two days after transfection with lipofectamine-2000. The combined antiproliferative effects of EZN3920 with gefitinib (EGFR inhibitor) were also examined in 8 ErbB inhibitor-sensitive and -insensitive tumor cell lines. In vivo: HER3 knockdown efficacy in liver and human tumors from 15PC-3 (prostate), A549 (lung) and N87 (gastric) nude mice xenograft models were examined after intravenous administration. Phospho-Akt (p-Akt) level was also monitored following the treatment. Scrambled LNA-ASONs and Molt-4 leukemia cell line served as negative controls. Results:In vitro, EZN3920 potently inhibited HER3 mRNA and protein levels in various tumor cells (IC50 Citation Information: In: Proc Am Assoc Cancer Res; 2009 Apr 18-22; Denver, CO. Philadelphia (PA): AACR; 2009. Abstract nr 4630.
A successful electroconvulsive treatment of neuroleptic malignant syndrome (1987)

A case of neuroleptic malignant syndrome (NMS) treated successfully with electroconvulsive therapy (ETC) is described. Repeated exposures of the patients to succinylcholine during ECT did not cause malignant hyperthermia. The efficacy of ECT is probably related to its facilitatory effect upon dopamine (DA) activity in CNS.
Time-resolved lasing action from single and coupled photonic crystal nanocavity array lasers emitting in the telecom band (2009)

We measure the lasing dynamics of single and coupled photonic crystal nanocavity array lasers fabricated in the indium gallium arsenide phosphide material system. Under short optical excitation, single cavity lasers produce pulses as fast as 11ps (full width at half maximum), while coupled cavity lasers show significantly longer lasing duration which is not explained by a simple rate equation model. A finite difference time domain simulation including carrier gain and diffusion suggests that asynchronous lasing across the nanocavity array extends the laser’s pulse duration.
M3ICRO: Machine Learning-Enabled Compact Photonic Tensor Core based on PRogrammable Multi-Operand Multimode Interference (2023)

Photonic computing shows promise for transformative advancements in machine learning (ML) acceleration, offering ultra-fast speed, massive parallelism, and high energy efficiency. However, current photonic tensor core (PTC) designs based on standard optical components hinder scalability and compute density due to their large spatial footprint. To address this, we propose an ultra-compact PTC using customized programmable multi-operand multimode interference (MOMMI) devices, named M3ICRO. The programmable MOMMI leverages the intrinsic light propagation principle, providing a single-device programmable matrix unit beyond the conventional computing paradigm of one multiply-accumulate (MAC) operation per device. To overcome the optimization difficulty of customized devices that often requires time-consuming simulation, we apply ML for optics to predict the device behavior and enable a differentiable optimization flow. We thoroughly investigate the reconfigurability and matrix expressivity of our customized PTC, and introduce a novel block unfolding method to fully exploit the computing capabilities of a complex-valued PTC for near-universal real-valued linear transformations. Extensive evaluations demonstrate that M3ICRO achieves a 3.4-9.6x smaller footprint, 1.6-4.4x higher speed, 10.6-42x higher compute density, 3.7-12x higher system throughput, and superior noise robustness compared to state-of-the-art coherent PTC designs, while maintaining close-to-digital task accuracy across various ML benchmarks. Our code is open-sourced at https://github.com/JeremieMelo/M3ICRO-MOMMI.
A comparison of Ultraflex diamond stents and Wallstents for palliation of distal malignant biliary strictures (2000)

OBJECTIVE:

The objective of this study was to compare the effectiveness of the Ultraflex Diamond stent and the Wallstent for the drainage of distal malignant biliary strictures.

METHODS:

The results obtained in 23 consecutive patients in whom the insertion of a Ultraflex Diamond stent had been attempted were compared with those obtained in 23 patients matched for age, gender, serum bilirubin, and diagnosis who had been treated with Wallstents.

RESULTS:

Biliary drainage was obtained in 100% of cases. More than one stent was required in 4% and 12% of patients treated with Ultraflex Diamond stents and Wallstents, respectively (p > 0.05). The first stent inserted did not provide adequate biliary drainage in four patients, because of the impaction of the proximal end of Wallstents into the bile duct wall (n = 2) and obstruction of the stent lumen by tumor tissue (one in each group). Procedure-related morbidity and mortality were 4%. Patients were followed-up for a mean of 228 days (range, 1 to 1262 days). During follow-up, bile duct obstruction relapsed in 5/22 and 6/21 patients treated with Ultraflex Diamond stents and Wallstents, respectively. Life table analysis of bile duct patency was similar with both stent models.

CONCLUSIONS:

Ultraflex Diamond stents are easy to insert and provide a high success rate of biliary drainage with minimal complication. Although long-term patency rates obtained with this stent were similar to those observed with Wallstents, no firm conclusion can be drawn in this regard due to the relatively small number of patients studied.
Recombinant Proteins ofCryptosporidium parvumInduce Proliferation of Mesenteric Lymph Node Cells in Infected Mice (2005)

Recombinant antigens of Cryptosporidium parvum, Cp900 and Cp40 but not Cp15, stimulated C. parvum-specific proliferative immune responses of mesenteric lymph node cells in C57BL/6J mice infected with different isolates (MD, GCH1, UCP, and IOWA) of C. parvum, indicating that both Cp900 and Cp40 are immunodominant targets of cellular immune responses during C. parvum infection.