gebhart/patrepeval huggingface dataset:
Porous mechanical metamaterials as interacting elastic charges (2017)

We present an analytical framework to describe the complex nonlinear response of two-dimensional porous mechanical metamaterials. We adopt a geometric approach to elasticity in which pores are represented by elastic charges, and show that this method captures with high level of accuracy both the shape deformation of individual pores as well as collective deformation patterns resulting from interactions between neighboring pores. Specifically, we show that quadrupoles and hexadecapoles - the two lowest order multipoles available in elasticity - are capable of matching the experimentally observed evolution in shape and relative orientation of the holes in a variety of periodic porous mechanical metamaterials. Our work demonstrates the ability of elastic charges to capture the physics of highly deformable porous solids and paves the way to the development of new theoretical frameworks for the description and rational design of porous mechanical metamaterials.
In vivo stimulation of the insulin receptor kinase in human skeletal muscle. Correlation with insulin-stimulated glucose disposal during euglycemic clamp studies. (1991)

To assess the relationship between insulin receptor (IR) kinase activity and insulin action in vivo in humans, we measured glucose disposal rates (GDR) during a series of euglycemic clamp studies. Simultaneously, we measured IR kinase activity in IRs extracted from skeletal muscle obtained by needle biopsy at the end of each clamp. By preserving the phosphorylation state of the receptors as it existed in vivo at the time of biopsy, we could correlate GDR and IR kinase in skeletal muscle. Eight nondiabetic, nonobese male subjects underwent studies at insulin infusion rates of 0, 40, 120, and 1,200 mU/m2 per min. Kinase activity, determined with receptors immobilized on insulin agarose beads, was measured at 0.5 microM ATP, with 1 mg/ml histone, followed by SDS-PAGE. Insulin increased GDR approximately sevenfold with a half-maximal effect at approximately 100 microU/ml insulin and a maximal effect by approximately 400 microU/ml. Insulin also increased IR kinase activity; the half-maximal effect occurred at approximately 500-600 microU/ml insulin with a maximal 10-fold stimulation over basal. Within the physiologic range of insulin concentrations, GDR increased linearly with kinase activation (P less than 0.0006); at supraphysiologic insulin levels, this relationship became curvilinear. Half-maximal and maximal insulin-stimulated GDR occurred at approximately 20 and approximately 50% maximal kinase activation, respectively. These results are consistent with a role of the kinase in insulin action in vivo. Furthermore, they demonstrate the presence of a large amount of "spare kinase" for glucose disposal.
Improving SDN with InSPired Switches (2016)

In SDN, complex protocol interactions that require forging network packets are handled on the controller side. While this ensures flexibility, both performance and scalability are impacted, introducing serious concerns about the applicability of SDN at scale. To improve on these issues, without infringing the SDN principles of control and data planes separation, we propose an API for programming the generation of packets in SDN switches. Our InSP API allows a programmer to define in-switch packet generation operations, which include the specification of triggering conditions, packet's content and forwarding actions. To validate our design, we implemented the InSP API in an OpenFlow software switch and in a controller, requiring only minor modifications. Finally, we demonstrate that the application of the InSP API, for the implementation of a typical ARP-handling use case, is beneficial for the scalability of both switches and controller.
Attogram-level detection and relative sensitivity of strong electrophores by gas chromatography with electron capture detection (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAttogram-level detection and relative sensitivity of strong electrophores by gas chromatography with electron capture detectionJeffrey A. Corkill, Markus. Joppich, Simon H. Kuttab, and Roger W. GieseCite this: Anal. Chem. 1982, 54, 3, 481–485Publication Date (Print):March 1, 1982Publication History Published online1 May 2002Published inissue 1 March 1982https://pubs.acs.org/doi/10.1021/ac00240a029https://doi.org/10.1021/ac00240a029research-articleACS PublicationsRequest reuse permissionsArticle Views170Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Stereophonic spectrogram segmentation using Markov random fields (2012)

There is a good amount of similarity between source separation approaches that use spectrograms captured from multiple microphones and computer vision algorithms that use multiple images for segmentation problems. Just as one would use Markov random fields (MRF) to solve image segmentation problems, we propose a method of modeling source separation using MRFs, and then solving such problems via common MRF inference methods. To this end, as a preprocessing, we convert stereophonic spectrograms into a integrated form based on their inter-channel level differences (ILD), which is a procedure analogous to getting a disparity map from stereo images for matching problems. Given the ILD matrix as an observed image, we estimate latent labels which stand for the responsibility of each spectrogram's time/frequency bin to a specific sound source. It is shown that the proposed method shows reasonable separation performance in a variety of mixing environments including online separation and moving sources. We expect this new way of formulating source separation problems to help exploit advantages of probabilistic graphical models and the recent advances in low-power, high-performance hardware suited for such tasks.
Méthode de conception automatisée appliquée aux lignes composites main gauche/droite (2009)

National audience
The Influence of Religiosity and Stigma on Mental Health Outcomes for an African American and Latino Clinical Sample (2013)

Few studies have explored the link between religion and mental health, especially among ethnic minority groups in the U.S. Although African Americans and Latinos have been found to rely heavily on their religious faith in order to cope with adversities in their lives, both ethnic groups have been traditionally underrepresented in this line of work. Thus, little is known about the religion-mental health link as it applies to these minority groups.\nThe aims of the present study were as follows: (1) to determine whether various forms of religion (self-rated religiosity, church attendance, and religious beliefs and practices) would be predictive of fewer psychiatric symptoms among African American and Latino individuals with mental illness, (2) to determine whether the religion-mental health link would remain significant even after controlling social support and other demographic variables, and (3) to determine whether the religion-mental health link would be moderated by the extent to which individuals internalize the stigma of mental illness.\nOne hundred and four African American and Latino individuals with a history of mental illness, substance abuse, and/or psychological treatment completed a self-report questionnaire. Study results indicated that out of the three religious measures used in the present study, only self-rated religiosity negatively and significantly predicted lower psychiatric symptomatology. This association was significant even after social support and other variables (e.g., income, gender) were controlled for in the study. Stigma internalization was also shown to positively and significantly predict psychiatric symptoms, as well as moderate the religion- mental health association.
Time-lapse videomicroscopy of HT-29 colonic cancer cells treated with CDDP NP from A Squalene-Based Nanomedicine for Oral Treatment of Colon Cancer (2023)

&lt;p&gt;Video 3 shows the toxicity of SQ-CDDP NP (8 microM) on HT-29 cells.&lt;/p&gt;
Residual calibration error impact on SMOS SLL performance (2014)

SMOS Side Lobe Level (SLL), which is caused by the limited coverage of the measured visibility samples in the frequency domain, is responsible for non-negligible radiometric errors at pixels placed close to large brightness temperature transitions (e.g. coastline, ice-sea border, RFI, sun reflection, etc.). In order to mitigate this effect the visibility samples are tapered by means of a Blackman window before the image inversion procedure is undertaken. However, the theoretical SLL performance of such a specific taper is degraded by residual visibility calibration errors. Simulations performed in this work show that SLL performance is very sensitive to calibration errors and that the SLL performance of the rectangular window cannot be improved to a large extend, even in the case that calibration errors are constrained by very stringent requirements. Therefore, smarter inversion techniques or data handling procedures must be devised in the future to effectively deal with this issue.
Nucleotide sequence of theXenopus tropicalislarval β globin gene (1987)

Journal Article Nucleotide sequence of the Xenopus tropicalis larval β globin gene Get access Walter Knöchel, Walter Knöchel Institut für Molekularbiologie und Biocherrue, Freie Universität BerlinArnimallee 22, D-1000 Berlin 33, FRG Search for other works by this author on: Oxford Academic PubMed Google Scholar James Beck, James Beck Institut für Molekularbiologie und Biocherrue, Freie Universität BerlinArnimallee 22, D-1000 Berlin 33, FRG Search for other works by this author on: Oxford Academic PubMed Google Scholar Wolfgang Meyerhof Wolfgang Meyerhof Institut für Molekularbiologie und Biocherrue, Freie Universität BerlinArnimallee 22, D-1000 Berlin 33, FRG Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 15, Issue 23, 10 December 1987, Page 10062, https://doi.org/10.1093/nar/15.23.10062 Published: 10 December 1987 Article history Received: 14 October 1987 Published: 10 December 1987
A modular process for integrating thick polysilicon MEMS devices with sub-micron CMOS (2003)

A new MEMS process module, called Mod MEMS, has been developed to monolithically integrate thick (5-10um), multilayer polysilicon MEMS structures with sub-micron CMOS. This process is particularly useful for advanced inertial MEMS products such as automotive airbag accelerometers where reduced cost and increased functionality is required, or low cost, high performance gyroscopes where thick polysilicon (>6um) and CMOS integration is required to increase poly mass and stiffness, and reduce electrical parasitics in order to optimize angular rate sensing. In this paper we will describe the new modular process flow, development of the critical unit process steps, integration of the module with a foundry sub-micron CMOS process, and provide test data on several inertial designs fabricated with this process.
Iron oxide-modified nanoporous geopolymers for arsenic removal from ground water (2015)

Composite materials of hierarchically porous geopolymer and amorphous hydrous ferric oxide were produced and characterized as a new potentially cost-effective arsenic adsorbent. The arsenic removal capabilities of the iron (hydr)oxide (HFO) media were carried out using batch reactor experiments and laboratory scale continuous flow experiments. The Rapid Small-Scale Column Tests (RSSCT) were employed to mimic a scaled up packed bed reactor and the toxicity characteristic leaching procedure (TCLP) test of arsenic adsorbed solid material was carried out to investigate the mechanical robustness of the adsorbent. The best performing media which contained ~20 wt% Fe could remove over 95 g of arsenic per gram of dry media from arsenic only water matric. The role of the high porosity in arsenic adsorption characteristics was further quantified in conjunction with accessibility of the adsorption sites. The new hierarchically porous geopolymer-based composites were shown to be a good candidate for cost-effective removal of arsenic from contaminated water under realistic conditions owing to their favorable adsorption capacity and very low leachability.
Long-Range Fiber Transmission of Optical Vortices (2011)

We use specialty fiber (“vortex fiber”), to create and propagate orbital angular momentum states over ~kilometer lengths in telecom band (~1550nm). The spiral phase structure of the vortex beams was confirmed by interference with a Gaussian reference. This result is an important step toward achieving long-range classical and quantum communication links using orbital angular momentum of light.
Photoinduced nucleation in supersaturated isoprene vapor: The mechanism of photopolymerization (1989)

Homogeneous nucleation and photochemical polymerization in supersaturated isoprene vapor were investigated using a diffusion cloud chamber. The mechanism of photoinitiation appears to involve the photolysis of a volatile product which results from the primary photodecomposition process. The photonucleation results from direct propagation as well as recombination of polymer molecules. At very low supersaturation ratio (e.g., 1.2), recombinative termination becomes the only possible way to achieve the tunable size required for the nucleation. A nonsteady state experiment allows us to resolve the nucleation spectrum into contributions due to polymers resulting from recombination and those due to direct propagation.
A novel bioreactor for the dynamic flexural stimulation of tissue engineered heart valve biomaterials (2003)

A novel bioreactor was developed for the purpose of studying the effect of dynamic flexural stimulation on the properties of tissue engineered heart valve (TEHV) scaffolds and constructs. While pulse duplicator and flow loop bioreactors have shown promise in the development of functional tissue engineered cardiovascular constructs, these devices present several drawbacks when applied to the study of fundamental biomechanical phenomena, including: small sample capacity, anatomical sample geometry, and coupled mechanical stimuli. In contrast, our bioreactor was designed to provide a simple, user-controllable mode of mechanical stimulation; cyclic three-point bending; offer a sufficient sample capacity for statistically significant comparisons at multiple time points, and accommodate a simple sample geometry amenable to mechanical testing. The bioreactor has the capacity to dynamically flex twelve rectangular samples (2.5 /spl times/ 0.75 /spl times/ 0.2 cm) under sterile conditions in a humidified cell culture incubator operating at 37/spl deg/C and 5 % CO/sub 2/.
Soluble Form of Heparin-binding EGF-like Growth Factor Contributes to Retinoic Acid-induced Epidermal Hyperplasia (2005)

Heparin-binding EGF-like growth factor (HB-EGF), a member of the EGF-family, is thought to be important for keratinocyte functions. HB-EGF is first synthesized as a membrane-anchored form, and its soluble form is released by ectodomain shedding. Here we investigate the role of HB-EGF in epidermal hyperplasia induced by all-trans retinoic acid (tRA) treatment. HB-EGF is normally expressed in epidermis of normal adult mice at very low levels, but topical tRA treatment results in epidermal hyperplasia, concomitant with the strong induction of HB-EGF expression in the suprabasal layer. tRA-induced epidermal hyperplasia was reduced both in the keratinocyte-specific HB-EGF null mice (K5-HB(del/del)) and knock-in mice expressing the uncleavable mutant form of HB-EGF (HB(uc/uc)), as compared with wild-type HB-EGF knock-in mice (HB(lox/lox)). Among ErbB tyrosine kinase receptors, EGF receptor (EGFR) and ErbB2 were selectively activated by tRA treatment in skin from wild-type mice, while the activation of these ErbB receptors was significantly reduced in the skin of HB-EGF null mice. These results indicate that expression of HB-EGF and generation of its soluble form, followed by activation of EGFR and ErbB2, are pivotal processes in tRA-induced epidermal hyperplasia.
Chaînes de Markov cachées multivariées à bruit corrélé non gaussien, avec applications à la segmentation du signal radar (2005)

We propose a multivariate signal model with temporal and spectral dependence, well-fitted for the modeling of Radar signals. The proposed model is a Hidden Markov Chain for which observations are Spherically Invariant Random Vectors (SIRV), and temporal correlation is described by a copula. It is still possible to estimate the parameters of the SIRV, and we study the robustness of the estimation under different kinds of copulas and various strength of dependence. Finally, we explore the influence of an omitted dependence for statistical segmentation of Radar signals based on Hidden Markov Chains.
<title>Scanning and rotating micromirrors using thermal actuators</title> (1997)

This paper reports on micromachined polysilicon scanning and rotating micromirrors and the development of a CMOS drive system. The micromirrors described in this research were developed at the Air Force Institute of Technology and fabricated using the DARPA-sponsored multi-user MEMS processes (MUMPs). The scanning micromirror is connected to the substrate using micro-hinges. This allows the mirror plate to rotate off the substrate surface and lock into a support mechanism. The angle between the scanning mirror and the substrate is modulated by driving the mirror with a thermal actuator array through a range of 20 degrees. For the rotating mirror, the mirror plate is attached to the substrate by three floating substrate hinges connected to a rotating base. Actuator arrays are also used to position the rotating mirror. A computer controlled electrical interface was developed which automates the positioning of both the scanning and rotating mirrors. The low operating voltages of the micromirror positioning mechanism makes the use of CMOS technology attractive; and the development of a digital interface allows for flexible operation of the devices. These designs are well suited for micro-optical applications such as optical scanners, corner cube reflectors, and optical couplers where electrical positioning of a mirror is desired.
Multiclass Cancer Classification Using Semisupervised Ellipsoid ARTMAP and Particle Swarm Optimization with Gene Expression Data (2007)

It is crucial for cancer diagnosis and treatment to accurately identify the site of origin of a tumor. With the emergence and rapid advancement of DNA microarray technologies, constructing gene expression profiles for different cancer types has already become a promising means for cancer classification. In addition to research on binary classification such as normal versus tumor samples, which attracts numerous efforts from a variety of disciplines, the discrimination of multiple tumor types is also important. Meanwhile, the selection of genes which are relevant to a certain cancer type not only improves the performance of the classifiers, but also provides molecular insights for treatment and drug development. Here, we use Semisupervised Ellipsoid ARTMAP (ssEAM) for multiclass cancer discrimination and particle swarm optimization for informative gene selection. ssEAM is a neural network architecture rooted in Adaptive Resonance Theory and suitable for classification tasks. ssEAM features fast, stable, and finite learning and creates hyperellipsoidal clusters, inducing complex nonlinear decision boundaries. PSO is an evolutionary algorithm-based technique for global optimization. A discrete binary version of PSO is employed to indicate whether genes are chosen or not. The effectiveness of ssEAM/PSO for multiclass cancer diagnosis is demonstrated by testing it on three publicly available multiple-class cancer data sets. ssEAM/PSO achieves competitive performance on all these data sets, with results comparable to or better than those obtained by other classifiers.
Oriented Nanoporous Lamellar Organosilicates Templated from Topologically Unsymmetrical Dendritic‐Linear Block Copolymers (2005)

Dendrimere zwischen Schichten: Umgebungsresponsive dendritisch-lineare Blockcopolymere aus Polyethylenoxid und einem von 2,2′-Bis(hydroxymethyl)propionsäure abgeleiteten Dendron (siehe Struktur) wurden zur Anordnung von verglastem Organosilicat in nanostrukturierte lamellare Morphologien genutzt. Thermolyse des Templats lieferte eine perforierte poröse Lamellarstruktur (4 nm) zwischen Organosilicatschichten (6–9 nm).
Local structural distortions, orbital ordering, and ferromagnetism in underdopedLa1−xSrxMnO3 (2015)

In order to elucidate the origin of the ferromagnetism found in underdoped $\mathrm{L}{\mathrm{a}}_{1\ensuremath{-}x}\mathrm{S}{\mathrm{r}}_{x}\mathrm{Mn}{\mathrm{O}}_{3}$, we have grown a series of single crystals with a fine step of doping and characterized them with a structural study and measurements of magnetization, resistivity, thermoelectric power, and thermal conductivity. The paramagnetic phase of the underdoped $\mathrm{L}{\mathrm{a}}_{1\ensuremath{-}x}\mathrm{S}{\mathrm{r}}_{x}\mathrm{Mn}{\mathrm{O}}_{3}$ is a small-polaron conductor. However, the Weiss constant extracted from the paramagnetic susceptibility shows a ferromagnetic coupling and tracks the Curie temperature. Given that the double exchange interaction cannot be delivered by the hopping motion of small polarons, we have made a systematic analysis of the structural changes with $x$ and studied whether the superexchange interaction can account for the ferromagnetic coupling found in the paramagnetic phase. Intrinsic local site distortions in $\mathrm{LaMn}{\mathrm{O}}_{3}$ change as $x$ increases in $\mathrm{L}{\mathrm{a}}_{1\ensuremath{-}x}\mathrm{S}{\mathrm{r}}_{x}\mathrm{Mn}{\mathrm{O}}_{3}$. The influence of the local structural distortion and the cooperative orbital ordering on lattice parameters have been demonstrated by a comparison between the measured change of lattice parameters versus hole doping and a simulation with the software SPuDs, in which rigid octahedra are assumed. Changes with $x$ of the bond length splitting in $\mathrm{Mn}{\mathrm{O}}_{6}$ octahedra induces an orbital mixing of $(3{x}^{2}\ensuremath{-}{r}^{2})+({y}^{2}\ensuremath{-}{z}^{2})\phantom{\rule{0.28em}{0ex}}\mathrm{or}\phantom{\rule{0.28em}{0ex}}(3{y}^{2}\ensuremath{-}{r}^{2})+({z}^{2}\ensuremath{-}{x}^{2})$, which progressively converts two-dimensional ferromagnetism in the parent perovskite $\mathrm{LaMn}{\mathrm{O}}_{3}$ into three-dimensional ferromagnetism. The correlation between the particular lattice distortions and the cooperative orbital ordering and orbital mixing can in turn be used to test the superexchange model by measuring the change of transition temperatures under uniaxial stress. Nearly identical uniaxial stress effects found in crystals of the mixed-valent $\mathrm{L}{\mathrm{a}}_{0.875}\mathrm{S}{\mathrm{r}}_{.125}\mathrm{Mn}{\mathrm{O}}_{3}$ and single-valent $\mathrm{LaM}{\mathrm{n}}_{0.5}\mathrm{G}{\mathrm{a}}_{0.5}{\mathrm{O}}_{3}$ confirm unambiguously that superexchange interactions play the dominant role in the ferromagnetic coupling of underdoped $\mathrm{L}{\mathrm{a}}_{1\ensuremath{-}x}\mathrm{S}{\mathrm{r}}_{x}\mathrm{Mn}{\mathrm{O}}_{3}$.