gebhart/patrepeval huggingface dataset:
Tolerance of Sustained Ventricular Fibrillation During Continuous-Flow Left Ventricular Assist Device Support (2017)

The widespread use of continuous-flow left ventricular assist devices for mechanical circulatory support has shown that long-term hemodynamic support is possible, even when a clinical "pulse" cannot be detected. We present the incidental discovery of ventricular fibrillation in 6 alert, hemodynamically stable patients supported only by a continuous-flow device (HeartMate II, n=5; Jarvik 2000, n=1). Ventricular fibrillation was found in 3 patients during routine outpatient follow-up visits and in 3 awaiting discharge from the hospital after device placement. Diagnosis was confirmed by electrocardiographic and echocardiographic studies. The average duration of mechanical circulatory support before ventricular fibrillation occurred was 221 ± 362 days (range, 5-864 d). All patients were conscious and ambulatory at the time of the arrhythmia. Three patients reported symptoms-primarily fatigue, nausea, and exertional dyspnea-that prompted evaluation. Serum chemistry analysis of blood drawn immediately after diagnosis showed no changes that suggested end-organ dysfunction. Three patients died of unrelated complications an average of 3.9 yr (range, 360-2,270 d) after the event. Two of the remaining 3 patients eventually underwent successful pump explantation, and one is on ongoing support. Our experience shows that it is possible for patients with continuous-flow left ventricular assist devices to remain hemodynamically stable while in ventricular fibrillation. Additional investigation is needed to determine whether defibrillator settings for these patients should be adjusted to limit delivery of shock therapy.
Synthesis of DNA Strands Site‐Specifically Damaged by C8‐Arylamine Purine Adducts and Effects on Various DNA Polymerases (2008)

C8-Arylamine-dG and C8-arylamine-dA adducts have been prepared using palladium cross-coupling chemistry. These adducts were subsequently converted into the corresponding 5'-O-DMTr-C8-arylamine-3'-O-phosphoramidites and then used for the automated synthesis of different site-specifically modified oligonucleotides. These "damaged" oligonucleotides have been characterized by ESI-MS, UV thermal stability assays, and circular dichroism, and they have been used in EcoRI assays as well as in primer extension studies using various DNA polymerases.
Suppression of Epididymal Sperm Antigenicity in the Rabbit by Uteroglobin and Transglutaminase in Vitro (1983)

There is evidence that the mammalian female genital tract is capable of responding immunologically when challenged with alloantigens. The antigenic properties of male gametes have been well delineated. However, it is only rarely that a female mammal ever responds immunologically to the male gametic antigens as a result of coitus. When a proposed mechanism of suppression of antigenicity of epididymal spermatozoa was tested experimentally, the results indicated that two proteins (uteroglobin and transglutaminase) present in the prostate may be responsible for suppressing sperm antigenicity in the rabbit.
MP13-10 TRENDS IN AMBULATORY CARE OF OLDER ADULTS WITH URINARY STONE DISEASE (2018)

number of total relatives with stones conferred an increased odds ratio for interval stone events ?1, bilaterality, and number of stone episodes ?6 (Table
A Pilot Study Comparing the Effects of Concurrent and Terminal Visual Feedback on Standing Balance in Older Adults (2022)

While balance training with concurrent feedback has been shown to improve real-time balance in older adults, terminal feedback may simplify implementation outside of clinical settings. Similarly, visual feedback is particularly well-suited for use outside the clinic as it is relatively easily understood and accessible via ubiquitous mobile devices (e.g., smartphones) with little additional peripheral equipment. However, differences in the effects of concurrent and terminal visual feedback are not yet well understood. We therefore performed a pilot study that directly compared the immediate effects of concurrent and terminal visual feedback as a first and necessary step in the future design of visual feedback technologies for balance training outside of clinical settings. Nineteen healthy older adults participated in a single balance training session during which they performed 38 trials of a single balance exercise including trials with concurrent, terminal or no visual feedback. Analysis of trunk angular position and velocity features recorded via an inertial measurement unit indicated that sway angles decreased with training regardless of feedback type, but sway velocity increased with concurrent feedback and decreased with terminal feedback. After removing feedback, training with either feedback type yielded decreased mean velocity, but only terminal feedback yielded decreased sway angles. Consequently, this study suggests that, for older adults, terminal visual feedback may be a viable alternative to concurrent visual feedback for short duration single-task balance training. Terminal feedback provided using ubiquitous devices should be further explored for balance training outside of clinical settings.
Low-dose cytarabine to prevent myeloid leukemia in children with Down syndrome: TMD Prevention 2007 study (2018)

Approximately 5% to 10% of children with Down syndrome (DS) are diagnosed with transient myeloproliferative disorder (TMD). Approximately 20% of these patients die within 6 months (early death), and another 20% to 30% progress to myeloid leukemia (ML-DS) within their first 4 years of life. The aim of the multicenter, nonrandomized, historically controlled TMD Prevention 2007 trial was to evaluate the impact of low-dose cytarabine treatment on survival and prevention of ML-DS in patients with TMD. Patients received cytarabine (1.5 mg/kg for 7 days) in case of TMD-related symptoms at diagnosis (high white blood cell count, ascites, liver dysfunction, hydrops fetalis) or detection of minimal residual disease (MRD) 8 weeks after diagnosis. The 5-year probability of event-free and overall survival of 102 enrolled TMD patients was 72 ± 5% and 91 ± 3%, respectively. In patients eligible for treatment because of symptoms (n = 43), we observed a significantly lower cumulative incidence (CI) of early death as compared with symptomatic patients in the historical control (n = 45) (12 ± 5% vs 33 ± 7%, <i>P</i><sub>Gray</sub> = .02). None of the asymptomatic patients in the current study suffered early death. However, the treatment of symptomatic or MRD-positive patients did not result in a significantly lower CI of ML-DS (25 ± 7% [treated] vs 14 ± 7% [untreated], <i>P</i><sub>Gray</sub> = .34 [per protocol analysis]; historical control: 22 ± 4%, <i>P</i><sub>Gray</sub> = .55). Thus, low-dose cytarabine treatment helped to reduce TMD-related mortality when compared with the historical control but was insufficient to prevent progression to ML-DS. This trial was registered at EudraCT as #2006-002962-20.
Microfluidic Metasurfaces: Broadband Wide‐Angle Multifunctional Polarization Converter via Liquid‐Metal‐Based Metasurface (Advanced Optical Materials 7/2017) (2017)

In article number 1600938, Din Ping Tsai, Ai-Qun Liu, and co-workers demonstrate a liquid-metal based metasurface for broadband wide-angle multifunctional polarization conversion in the different states of polarization—linear, circular, and elliptical—whereby such material is dynamically reconfigured through tuning of the L-shaped resonators. The bandwidth is larger than 60% and the angular tolerance is 45°. This is a significant milestone for metasurface applications such as smart radar and light manipulation for quantum computing and communication.
Evaluation of a Sludge Homogenization Pre-Conditioning Process for Increased Biogas Cogeneration Potential and Reduced Sludge Yields from Anaerobic Digestion (2010)

Evaluation of a Sludge Homogenization Pre-Conditioning Process for Increased Biogas Cogeneration Potential and Reduced Sludge Yields from Anaerobic DigestionRecently several technologies and process innovations have been proposed to reduce or eliminate the waste activated sludge (WAS) fraction resulting from treatment, or to render it more amenable to anaerobic digestion, a common sludge stabilization step, in order to maximize biogas production and the corresponding potential for energy cogeneration. Under WERF's 05- CTS-3 Evaluation of Processes to...Author(s)Julian SandinoDrury WhitlockJohn NovakMatt HigginsRoyce HammittPhilip KoundakjianRob StephensonScott LalibertePreston HoyAmanda DrewSourceProceedings of the Water Environment FederationSubjectSession 66: Advancements in Pre-Digestion Solids TreatmentDocument typeConference PaperPublisherWater Environment FederationPrint publication date Jan, 2010ISSN1938-6478SICI1938-6478(20100101)2010:12L.4769;1-DOI10.2175/193864710798182853Volume / Issue2010 / 12Content sourceWEFTECFirst / last page(s)4769 - 4787Copyright2010Word count187Subject keywordsSludge pre-conditioningsludge homogenizationco-generationsludge reductionanaerobic digestion
Exposure to Halothane and Enflurane Affects Learning Function of Murine Progeny (1981)

This study was conducted to assess the learning function of murine progeny born of mothers that had received either 1% or 2% halothane or 2% or 4% enflurane, on days 6 and 10 or days 14 and 17 or gestation. Their timed performance at the age of 6 to 7 weeks was compared in a maze with that of control mice of similar ages that had not been exposed to anesthetics prenatally. All mice exposed to halothane in utero performed poorly at first, especially the group with mothers exposed to 2% halothane on days 14 and 17 of pregnancy. By the 10th training period, the performance of all mice improved but remained significantly slower than control mice. The offsprings of mice exposed to enflurane also performed poorly on the first training period, but between the fifth and seventh training periods, made statistically significant progress. However, they too remained slower in maze performance than control mice. Although blood pressure and arterial blood gas studies were only performed on two pregnant mice, data obtained suggest that the anesthetics did not have sufficient effect on respiration to affect our results. Second generation offspring, born to dams exposed to 2% halothane in utero late in pregnancy and sired by normal unexposed males, were also consistently slower than control mice, indicating a possible genetic effect induced by the anesthetic.
Towards knowledge management in autonomic systems (2004)

The classical definition of knowledge management promises to get the right knowledge to the right people at the right time so they can make the best decision [G. Petrash, 1996]. Autonomic systems, on the other hand, are expected to find and apply the right knowledge for self-managing purposes without human intervention. This article discusses the components to be built around a system to enable self-healing and managing capabilities. These are defined and described in this article as self-knowledge, self-monitoring, self-learning, problem detection, diagnosis, and search and solution components. Interaction of these system components to make knowledge available for self-healing purposes is also discussed.
Uncovering the crystal defects within aragonite CaCO 3 (2022)

Knowledge of deformation mechanisms in aragonite, one of the three crystalline polymorphs of CaCO3, is essential to understand the overall excellent mechanical performance of nacres. Dislocation slip and deformation twinning were claimed previously as plasticity carriers in aragonite, but crystallographic features of dislocations and twins have been poorly understood. Here, utilizing various transmission electron microscopy techniques, we reveal the atomic structures of twins, partial dislocations, and associated stacking faults. Combining a topological model and density functional theory calculations, we identify complete twin elements, characters of twinning disconnection, and the corresponding twin shear angle (∼8.8°) and rationalize unique partial dislocations as well. Additionally, we reveal an unreported potential energy dissipation mode within aragonite, namely, the formation of nanograins via the pile-up of partial dislocations. Based on the microstructural comparisons of biogenic and abiotic aragonite, we find that the crystallographic features of twins are the same. However, the twin density is much lower in abiotic aragonite due to the vastly different crystallization conditions, which in turn are likely due to the absence of organics, high temperature and pressure differences, the variation in inorganic impurities, or a combination thereof. Our findings enrich the knowledge of intrinsic crystal defects that accommodate plastic deformation in aragonite and provide insights into designing bioengineering materials with better strength and toughness.
Impact of malignancy on outcomes in European patients with atrial fibrillation: A report from the ESC‐EHRA EURObservational research programme in atrial fibrillation general long‐term registry (2022)

In a large contemporary cohort of AF patients, active malignancy was independently associated with all-cause death, MACE and haemorrhagic events. Use of anticoagulants was not associated with a higher risk of all-cause death in patients with active malignancies.
Tailoring Optical Gradient Force and Optical Scattering and Absorption Force (2017)

The introduction of the concept of gradient force and scattering and absorption force is an important milestone in optical trapping. However the profiles of these forces are usually unknown, even for standard setups. Here, we successfully calculated them analytically via multipole expansion and numerically via Mie theory and fast Fourier transform. The former provides physical insight, while the latter is highly accurate and efficient. A recipe to create truly conservative energy landscapes is presented. These may open up qualitatively new features in optical manipulation.
Social media driven image retrieval (2011)

People often try to find an image using a short query and images are usually indexed using short annotations. Matching the query vocabulary with the indexing vocabulary is a difficult problem when little text is available. Textual user generated content in Web 2.0 platforms contains a wealth of data that can help solve this problem. Here we describe how to use Wikipedia and Flickr content to improve this match. The initial query is launched in Flickr and we create a query model based on co-occurring terms. We also calculate nearby concepts using Wikipedia and use these to expand the query. The final results are obtained by ranking the results for the expanded query using the similarity between their annotation and the Flickr model. Evaluation of these expansion and ranking techniques, over the Image CLEF 2010 Wikipedia Collection containing 237,434 images and their multilingual textual annotations, shows that a consistent improvement compared to state of the art methods.
Acute Myocardial Infarction: Tissue Characterization with T1ρ-weighted MR Imaging—Initial Experience (2004)

Acute myocardial injury was evaluated in 21 patients by using a contrast material-enhanced T1rho-weighted cine turbo field-echo magnetic resonance (MR) imaging sequence and a delayed-enhancement sequence. In 12 of 21 patients, conventional T1-weighted contrast-enhanced cine turbo field-echo MR images were also collected for direct comparison with T1rho-weighted images. Delayed-enhancement technique distinctly characterized irreversible injury (percentage enhancement, 588% +/- 344). With T1rho weighting, percentage enhancement of irreversibly injured myocardium was 68% +/- 41, compared with 23% +/- 24 without T1rho weighting (P <.006). The addition of T1rho weighting to contrast-enhanced cine turbo field-echo MR sequences may offer a new contrast enhancement mechanism for characterization of acutely infarcted myocardium.
Long-Term Results of Endoureterotomy for Benign Ureteral and Ureteroenteric Strictures (1997)

Endoureterotomy of benign ureteral strictures is associated with an excellent outcome (80% success at 3 years). Endoscopic treatment of ureteroenteric strictures is less successful but still offers a reasonable first step (32% 3-year success rate). For all strictures failure is likely if ipsilateral renal function is poor. For strictures longer than 1 cm. use of a stent 12F or greater and injection of triamcinolone appear to be beneficial.
UA wavefront control lab: design overview and implementation of new wavefront sensing techniques (2015)

We present an overview of the design of a new testbed for studying coronagraphic imaging and wavefront control using a variety of pupil and coronagraph architectures. The testbed is designed to explore optimal use of starlight (including starlight rejected by the coronagraph) for wavefront control, system self-calibration, and point spread function (PSF) calibration. It is also compatible with coronagraph designs for centrally obscured and segmented apertures, and includes shaped or apodized pupils, a range of focal plane masks and Lyot stops of multiple sizes, and an optional PIAA apodizing stage. Starlight is reflected and imaged from the focal plane mask and Lyot stop for low-order wavefront sensing. Both a segmented and a continuous sheet MEMS DM are included to simulate segmented telescope pupils, apply known test phase patterns, and implement a controllable phase apodization coronagraph. The testbed is adaptable and is currently being used to investigate three different techniques: (1) the differential optical transfer function (dOTF), (2) low-order wavefront sensing (LOWFS) with a hybrid-Lyot coronagraph, and (3) linear dark field control (LDFC).
Shadow Chasing : A Resource Allocation Scheme For Heterogeneous Networks (2012)

In this paper, we propose a resource allocation scheme for interference mitigation in heterogeneous networks to serve both Macrocell User Equipments (MUEs) and Home User Equipments (HUEs). In the proposed Shadow Chasing scheme, the Home eNB (HeNB) uses Downlink Control Information (DCI) together w
Integral framework for acquiring and evolving situations in smart environments (2010)

Smart environments enhance user capabilities and comfort by providing new services and automated service execution based on sensed user activity. Though, when becoming really “smart”, such environments should not only provide some service automation,
ChemInform Abstract: Enantioselective Synthesis of Alkyne‐Substituted Quaternary Carbon Stereogenic Centers Through NHC—Cu‐Catalyzed Allylic Substitution Reactions with (iBu)2(Alkynyl)aluminum Reagents. (2011)

Abstract The enantioselective synthesis of small organic molecules containing readily differentiable alkyne and alkene groups such as (III) is described.
Tutorial: The core photonic networks-where are things heading? (2009)

Telecommunications carriers are under great economic pressure to keep their core networks cost effective. To address that, they need to keep reducing the cost-per-bit in the core IP routers and switches as well as the optical transport network which interconnects them. We will discuss the resulting desires for the transport technologies and temper those with Capacity Crunch issues. We will then explore alternate network architectures to better utilize the transport resources. These will include consideration of the pros and cons of a sub-wavelength grooming layer between the Layer 2/3 routers and Layer 1 transport. We will then describe ways to make the “ROADM” layer truly reconfigurable (remotely reconfigurable) and its value.
Effect of the Hydrofluoroether Cosolvent Structure in Acetonitrile-Based Solvate Electrolytes on the Li+ Solvation Structure and Li–S Battery Performance (2017)

We evaluate hydrofluoroether (HFE) cosolvents with varying degrees of fluorination in the acetonitrile-based solvate electrolyte to determine the effect of the HFE structure on the electrochemical performance of the Li-S battery. Solvates or sparingly solvating electrolytes are an interesting electrolyte choice for the Li-S battery due to their low polysulfide solubility. The solvate electrolyte with a stoichiometric ratio of LiTFSI salt in acetonitrile, (MeCN)<sub>2</sub>-LiTFSI, exhibits limited polysulfide solubility due to the high concentration of LiTFSI. We demonstrate that the addition of highly fluorinated HFEs to the solvate yields better capacity retention compared to that of less fluorinated HFE cosolvents. Raman and NMR spectroscopy coupled with ab initio molecular dynamics simulations show that HFEs exhibiting a higher degree of fluorination coordinate to Li<sup>+</sup> at the expense of MeCN coordination, resulting in higher free MeCN content in solution. However, the polysulfide solubility remains low, and no crossover of polysulfides from the S cathode to the Li anode is observed.
Automatic classification of pathological myopia in retinal fundus images using PAMELA (2010)

Pathological myopia is the seventh leading cause of blindness. We introduce a framework based on PAMELA (PAthological Myopia dEtection through peripapilLary Atrophy) for the detection of pathological myopia from fundus images. The framework consists of a pre-processing stage which extracts a region of interest centered on the optic disc. Subsequently, three analysis modules focus on detecting specific visual indicators. The optic disc tilt ratio module gives a measure of the axial elongation of the eye through inference from the deformation of the optic disc. In the texturebased ROI assessment module, contextual knowledge is used to demarcate the ROI into four distinct, clinically-relevant zones in which information from an entropy transform of the ROI is analyzed and metrics generated. In particular, the preferential appearance of peripapillary atrophy (PPA) in the temporal zone compared to the nasal zone is utilized by calculating ratios of the metrics. The PPA detection module obtains an outer boundary through a level-set method, and subtracts this region against the optic disc boundary. Temporal and nasal zones are obtained from the remnants to generate associated hue and color values. The outputs of the three modules are used as in a SVM model to determine the presence of pathological myopia in a retinal fundus image. Using images from the Singapore Eye Research Institute, the proposed framework reported an optimized accuracy of 90% and a sensitivity and specificity of 0.85 and 0.95 respectively, indicating promise for the use of the proposed system as a screening tool for pathological myopia.
An investigation of circular resist residue defects in the development of a flash memory process flow (2002)

This paper presents an investigation into the impact of resist residue defects discovered during the development of a new flash memory process flow. Previously, it was reported that resist residue defects are inherently present in many types of DUV resist processing. However, these residues were largely considered to be "nuisance" defects due to their location and very subtle physical characteristics. The newly developed process flow revealed that this defect source is in fact capable of producing "killer" defects at very high densities. This work begins with a review of the original investigation into the source and characteristics of the defect. It follows with a critical area analysis calculation to estimate the yield impact of varying degrees of this problem. It then discusses how the surface preparation and product interact with the lithography process to impact the formation of these resist residue defects. A model explaining the defect formation mechanism is presented and explanations of the leverage gained through various process modifications are given based on this model.