gebhart/patrepeval huggingface dataset:
Novel meta-surface design synthesis via nature-inspired optimization algorithms (2011)

Heuristic numerical optimization algorithms have been gaining interest over the years as the computational power of the digital computers increases at an unprecedented level every year. While mature techniques such as the Genetic Algorithm increase their application areas, researchers also try to come up with new algorithms by simply observing the highly tuned processes provided by the nature. In this dissertation, the well-known Genetic Algorithm (GA) will be utilized to tackle various novel electromagnetic optimization problems, along with parallel implementation of the Clonal Selection Algorithm (CLONALG) and newly introduced the Wind Driven Optimization (WDO) technique. The utility of the CLONALG parallelization and the efficiency of the WDO will be illustrated by applying them to multi-dimensional and multi-modal electromagnetics problems such as antenna design and metamaterial surface synthesis. 
One of the metamaterial application areas is the design synthesis of 90 degrees rotationally symmetric ultra-small unit cell artificial magnetic conducting (AMC) surfaces. AMCs are composite metallo-dielectric structures designed to behave as perfect magnetic conductors (PMC) over a certain frequency range, those exhibit a reflection coefficient magnitude of unity with an phase angle of zero degrees at the center of the band. The proposed designs consist of ultra small sized frequency selective surface (FSS) unit cells that are tightly packed and highly intertwined, yet achieve remarkable AMC band performance and field of view when compared to current state-of-the-art AMCs. In addition, planar double-sided AMC (DSAMC) structures are introduced and optimized as AMC ground planes for low profile antennas in composite platforms and separator slabs for vertical antenna applications. The proposed designs do not possess complete metallic ground planes, which makes them ideal for composite and multi-antenna systems. The versatility of the DSAMC slabs is also illustrated where designs with the other face of the slab still exhibits properties of an AMC. 
Another metamaterial design synthesis targets optimization of metallo-dielectric slabs to act as low-loss matched impedance magneto-dielectric metamaterials (MIMDM). Such designs provide magneto-dielectric material properties over a certain frequency range, allowing miniaturization of planar antennas when used as substrates. Similarly, MIMDM slabs can be designed for the absorber applications, where design equations for synthesizing such absorber materials from MIMDM are established. 
Finally, small sized rotationally symmetric unit cells are designed and employed as planar electromagnetic bandgap structures for microstrip patch antenna mutual coupling reduction.
Nonlinear coupling between the surface and volume modes of an oscillating bubble (1995)

An experimental study was conducted of the nonlinear coupling between the surface and volume modes of an oscillating bubble. Through this coupling, the surface modes of a bubble can produce monopole sound radiation, which has a higher radiation efficiency than the surface modes. A hydrophone and a hypodermic needle, connected to an air supply, were submerged in water in a small (7.1×7.1×7.7 cm3) sealed cell that was also connected to a regulated vacuum system for control of the ambient pressure. The sound radiation produced by releasing a bubble from the needle was monitored by a hydrophone and displayed on a digital oscilloscope. Two high-speed video cameras simultaneously recorded the radial motion of the bubble and the sound radiation trace as displayed on an analog oscilloscope. At low ambient pressures (i.e., a few cm Hg), it was observed that after the bubble creation sound died out, a sound of the same frequency but with a lower and relatively constant magnitude followed. Therefore, it is believed that these subsequent acoustical emissions are evidence of the coupling between the surface and the volume modes of the bubble. Observation of a constant phase angle between the surface oscillations of the bubble and the radiated sound suggests a causal relationship.
High-Speed Optical WDM-to-TDM Conversion Using Fiber Nonlinearities (2010)

We experimentally demonstrate several high-speed wavelength division multiplexing (WDM) to time division multiplexing (TDM) conversion schemes by using different nonlinearities in highly nonlinear fiber (HNLF). 40-160-Gb/s WDM-to-TDM conversion using cross-phase modulation (XPM) and 160-320-Gb/s conversion based on supercontinuum generation are shown. Furthermore, we investigate a different kind of HNLF, and demonstrate 40-80-Gb/s WDM-to-TDM conversion using XPM in a 0.8-m bismuth oxide HNLF (Bi-HNLF). Less than 3-dB power penalty is obtained for each case.
On Low Complexity Detection for QAM Isomorphic Constellations (2017)

Despite of the known gap from the Shannon's capacity, several standards are still employing QAM or star shape constellations, mainly due to the existing low complexity detectors. In this paper, we investigate the low complexity detection for a family of QAM isomorphic constellations. These constellations are known to perform very close to the peak-power limited capacity, outperforming the DVB-S2X standard constellations. The proposed strategy is to first remap the received signals to the QAM constellation using the existing isomorphism and then break the log likelihood ratio computations to two one dimensional PAM constellations. Gains larger than 0.6 dB with respect to QAM can be obtained over the peak power limited channels without any increase in detection complexity. Our scheme also provides a systematic way to design constellations with low complexity one dimensional detectors. Several open problems are discussed at the end of the paper.
Performance and Cost Evaluation of Fixed Relay Nodes in Future Wide Area Cellular Networks (2007)

Future cellular networks are expected to provide significantly higher capacity than today's systems. This might require a denser access point deployment, with a potential increase in network deployment cost as a consequence. A promising way to reduce cost is a multi-hop deployment where wireless relay nodes (RN) are introduced to enhance capacity and coverage. In this paper, a deployment procedure for a static radio environment is considered, adding RNs incrementally as a complement to initially deployed macro base stations (BS). Different strategies of deploying BSs and RNs, providing equal service levels, are analyzed from a cost perspective. We develop a methodology that can determine and compare the most cost efficient deployment mixes of BSs and RNs. Further, we compare a deployment of macro BSs and relays with a deployment of macro BSs and micro BSs. Results show that relays are more cost efficient if the micro BS cost is between 10 and 15 % higher compared to the cost of an RN.
Focus : Adaptation des espèces et contamination des milieux ? (2010)

Les quelques réflexions présentées ici permettent de faire le point des connaissances sur l'adaptation des espèces et la contamination des milieux : les liens et les conséquences.
Transition Metal Catalyzed CO/Olefin Co-Polymerization in Room Temperature Ionic Liquids (2002)

The palladium-catalyzed co-polymerization of styrene and CO in ionic liquids has been investigated. Using the hydrophobic ionic liquid, 1-hexylpyridinium bis(trifluoromethanesulfonyl)imide, as solvent gave improved yields and increased molecular weights compared to the same reactions in methanol. The influence of the ionic liquid solvent, the nature and concentration of the palladium catalyst, and recycling of the liquid catalyst system are discussed.
Assisted Fontan procedure: animal and in vitro models and computational fluid dynamics study☆☆☆ (2010)

Fontan connection with intermittent compression by wrapped latissimus dorsi (LD) was tested in vivo, in vitro and by means of computational fluid dynamics (CFD). Experimental study: LD was conditioned in four pigs for three weeks before Fontan connection by valved conduit wrapped with LD. Mock circuit: Inflatable cuff wrapped around valved conduit provided intermittent external compression, with pressure and flow measured at driving pressure of 8 or 16 mmHg. CFD study: A circuit was tested for possible increase above basal flow (4 l/min) with intermittent external compression. Experimental study: Intermittent conduit compression by LD provided mean 7% decrease of baseline PA pressure, with simultaneous flow increase of 2%. Mock circuit: By raising the driving pressure from 8 to 16 mmHg, the flow increased with baseline PVR (56%) and with elevated PVR (80%). Total pulmonary flow was reduced during intermittent external compression with both baseline and elevated PVR. CFD study: Compression with 13.0 mmHg provided 4.9% increase of total pulmonary flow with substantial increase of the peak flow (92%). In vivo and in vitro, the increased flow produced by compressing a conduit was confounded by the inevitable intermittent flow restriction. Mathematical model using lower pressure for intermittent external compression showed potential for increase in pulmonary flow.
ChemInform Abstract: Synthesis of a Phosphonate Analogue of Sialic Acid (Neu5Ac) Using Indium‐Mediated Allylation of Unprotected Carbohydrates in Aqueous Media. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Data for Bolometer operating at the threshold for circuit quantum electrodynamics (2020)

Data in figures of publication "Bolometer operating at the threshold for circuit quantum electrodynamics" published in Nature.
Oxidation states and magnetism of Fe nanoparticles prepared by a laser evaporation technique (1996)

Nanoparticles of iron and iron oxide have been prepared in a thermal diffusion cloud chamber using pulsed laser evaporation. SEM/TEM studies of these particles reveal a size distribution with a mean diameter of about 60 Å. This is consistent with the mean particle size estimated from the magnetic data. The oxidation levels of these nanoparticles prepared at different partial oxygen pressures were investigated using FTIR. All the samples are found to exhibit superparamagnetism with blocking temperatures ranging from 50 K to above room temperature. Magnetic anisotropy constants are calculated from the frequency dependence of the blocking temperatures are found to be one quarter of magnitude higher than is known for the bulk.
Sequential cancer immunotherapy: targeted activity of dimeric TNF and IL-8 (2009)

Polymorphonuclear neutrophils (PMNs) are potent effectors of inflammation and their attempts to respond to cancer are suggested by their systemic, regional and intratumoral activation. We previously reported on the recruitment of CD11b+ leukocytes due to tumor site-specific enrichment of TNF activity after intravenous administration of a dimeric TNF immunokine with specificity for fibroblast activation protein (FAP). However, TNF-induced chemo-attraction and extravasation of PMNs from blood into the tumor is a multistep process essentially mediated by interleukin 8. With the aim to amplify the TNF-induced and IL-8-mediated chemotactic response, we generated immunocytokines by N-terminal fusion of a human anti-FAP scFv fragment with human IL-8 (IL-8(72)) and its N-terminally truncated form IL-8(3-72). Due to the dramatic difference in chemotaxis induction in vitro, we favored the mature chemokine fused to the anti-FAP scFv for further investigation in vivo. BALB/c nu/nu mice were simultaneously xenografted with FAP-positive or -negative tumors and extended chemo-attraction of PMNs was only detectable in FAP-expressing tissue after intravenous administration of the anti-FAP scFv-IL-8(72) construct. As TNF-activated PMNs are likewise producers and primary targets for IL-8, we investigated the therapeutic efficacy of co-administration of both effectors: Sequential application of scFv-IL-8(72) and dimeric IgG1-TNF fusion proteins significantly enhanced anti-tumor activity when compared either to a single effector treatment regimen or sequential application of non-targeted cytokines, indicating that the tumor-restricted sequential application of IL-8(72) and TNF is a promising approach for cancer therapy.
Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer (2016)

Chronic lymphocytic leukemia (CLL) is the most common human leukemia, and transgenic mouse studies indicate that activation of the T-cell leukemia/lymphoma 1 (TCL1) oncogene is a contributing event in the pathogenesis of the aggressive form of this disease. While studying the regulation of TCL1 expression, we identified the microRNA cluster miR-4521/3676 and discovered that these two microRNAs are associated with tRNA sequences and that this region can produce two small RNAs, members of a recently identified class of small noncoding RNAs, tRNA-derived small RNAs (tsRNAs). We further proved that miR-3676 and miR-4521 are tsRNAs using Northern blot analysis. We found that, like ts-3676, ts-4521 is down-regulated and mutated in CLL. Analysis of lung cancer samples revealed that both ts-3676 and ts-4521 are down-regulated and mutated in patient tumor samples. Because tsRNAs are similar in nature to piRNAs [P-element-induced wimpy testis (Piwi)-interacting small RNAs], we investigated whether ts-3676 and ts-4521 can interact with Piwi proteins and found these two tsRNAs in complexes containing Piwi-like protein 2 (PIWIL2). To determine whether other tsRNAs are involved in cancer, we generated a custom microarray chip containing 120 tsRNAs 16 bp or more in size. Microarray hybridization experiments revealed tsRNA signatures in CLL and lung cancer, indicating that, like microRNAs, tsRNAs may have an oncogenic and/or tumor-suppressor function in hematopoietic malignancies and solid tumors. Thus, our results show that tsRNAs are dysregulated in human cancer.
Effect of Austenite Grain Size on Sulfide Stress Cracking Resistance of Low Alloy Martensitic Steels. (1992)

Effect of grain size on sulfide stress cracking (SSC) resistance, thought to be an important metallurgical factor, is not clearly understood. There are some conflicting experimental results about grain size effect on SSC resistance. In this paper, effect of austenite grain size of low alloy tempered martensite steel was in:vestigated using a constant load SSC test, considering their correlation with chemical compositions. An Rs value (SSCthreshold stress/yield strength) begins to decrease with increase in yield strength at the yield strength equal to a85. Fractographic study reveals that cr~5 corresponds to the minimum yield strength for the occurrence of intergranular fracture. ( T~5 rises with refinement in austenite grains, while Rs is not affected by austenite grain size at yield strengths below a85 (T~5 at a constant grain size is influenced also by chemical compositions, WhenRs is plotted against its tensile strength, no effect of austenite grain size, however, appears. The proposed model shows that grain refinement strengthening apparently increases a85 KEYWORDS: sulfide stress cracking
Enhanced development of porcine embryos cloned from bone marrow mesenchymal stem cells (2006)

In the present study, we have characterized an isolated population of porcine bone marrow mesenchymal stem cells (MSCs) for multilineage commitment and compared the developmental potential of cloned embryos with porcine MSCs and fetal fibroblasts (FFs). MSCs exhibited robust alkaline phosphatase activity and later transformed into mineralized nodules following osteoinduction. Furthermore, MSCs underwent adipogenic and chondrogenic differentiation by producing lipid droplets and proteoglycans, respectively. Primary cultures of FFs from a female fetus at ~30 day of gestation were established. Donor cells at 3-4 passage were employed for nuclear transfer (NT). Cell cycle analysis showed that the majority of MSCs in confluence were in the G0/G1 stage. Cumulus-oocyte complexes were matured and fertilized in vitro (IVF) as control. The cleavage rate was significantly (P<0.05) higher in IVF than in NT embryos with MSCs and FFs (84.54.6% vs. 52.25.4% and 50.85.2%, respectively). However, blastocyst rates in IVF and NT embryos derived from MSCs (20.62.5% and 18.43.0%) did not differ, but were significantly (P<0.05) higher than NT derived from FFs (9.52.1%). Total cell number and the ratio of ICM to total cells among blastocysts cloned from MSCs (34.45.2 and 0.380.08, respectively) were significantly (P<0.05) higher than those from FFs (22.65.5 and 0.180.12, respectively). Proportions of TUNEL positive cells in NT embryos from FFs (7.31.8%) were significantly (P<0.05) higher than in MSCs (4.61.3%) and IVF (2.50.9%). The results clearly demonstrate that multipotent bone marrow MSCs have a greater potential as donor cells than FFs in achieving enhanced production of cloned porcine embryos.
Challenges and design principles of large scale tactical network architecture (2010)

Modern tactical communications systems are moving towards Internet-style system architectures to support information sharing for improving overall mission effectiveness. Development of such large scale communications systems presents various system design challenges. Research works discussed in this thesis are motivated by the technical challenges commonly encountered during the development of several large scale communications systems and proposes system-level design principles in overcoming these technical challenges. The first part of this thesis addresses system-level quality of service issues by modeling and simulation of an a oat wide area network system architecture. This simulation study investigates the system performance of real-time applications and provides quality of service design recommendations. The second part of this thesis proposes a consolidated network architecture for designing an a oat local area network system. A simulated prototype system is developed to investigate the system performance trade-off in the proposed consolidated network architecture. The third part of this thesis proposes an automatic dynamic resource management system architecture to efficiently manage shared computing resources in resource-constrained network environments without any human operator intervention. Test results in this experimental study demonstrates improved network performance when a communications system employs the automatic dynamic resource management software. Finally, the last part of this thesis proposes a reliable data aggregation and dissemination framework for tactical communications systems operating in disruptive networking environments with intermittent network connectivity. A prototype system is developed and implemented to demonstrate that the proposed framework can ensure reliable data delivery which is beneficial to the current and future development of tactical communications system architectures.
This thesis makes several significant research contributions in designing a large scale communications system. First of all, the thesis suggests a simulation methodology for developing simulation models to study the performance of a large scale communications system and makes recommendations on system-level quality of service design. Secondly, the thesis reduces the complexity of future communications system design by proposing a consolidated system architecture. Thirdly, an automatic dynamic resource management software prototype is developed to alleviate resource contention issues commonly found in the tactical networking environments. Fourthly, a reliable data aggregation and dissemination framework is proposed and its function is demonstrated. The proposed framework can accurately infer meaningful messages from a large sensor data set and can reliably deliver the messages to the appropriate network destinations. Finally, the thesis organizes all of these relevant system-level design experiences and recommends system design principles for developing future large scale communications systems.
Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin (2010)

Disrupted-in-schizophrenia 1 (DISC1) has emerged as a schizophrenia-susceptibility gene affecting various neuronal functions. In this study, we characterized Mitofilin, a mitochondrial inner membrane protein, as a mediator of the mitochondrial function of DISC1. A fraction of DISC1 was localized to the inside of mitochondria and directly interacts with Mitofilin. A reduction in DISC1 function induced mitochondrial dysfunction, evidenced by decreased mitochondrial NADH dehydrogenase activities, reduced cellular ATP contents, and perturbed mitochondrial Ca(2+) dynamics. In addition, deficiencies in DISC1 and Mitofilin induced a reduction in mitochondrial monoamine oxidase-A activity. The mitochondrial dysfunctions evoked by the deficiency of DISC1 were partially phenocopied by an overexpression of truncated DISC1 that is associated with schizophrenia in human. DISC1 deficiencies induced the ubiquitination of Mitofilin, suggesting that DISC1 is critical for the stability of Mitofilin. Finally, the mitochondrial dysfunction induced by DISC1 deficiency was partially reversed by coexpression of Mitofilin, confirming a functional link between DISC1 and Mitofilin for the normal mitochondrial function. According to these results, we propose that DISC1 plays essential roles for mitochondrial function in collaboration with a mitochondrial interacting partner, Mitofilin.
Characteristics of Physiological Tremor in Five Fingers and Evaluations of Fatigue of Fingers in Typing. (1992)

Physiological tremor, which is the invisible mechanical vibration of body part, was measured for five fingers. It was obtained that the power spectrum always has two peaks at 10 and 25Hz for each of the five fingers. The peaks were considered to be generated in the following two loop systems: The component of the lower frequency originated from the central nervous system as a long loop, and that of the higher frequency originated from the muscle-spine loop system as a short loop. The total power, which was the sum of power spectra ranging from 1.5 to 50Hz, was defined as an evaluation index, and it showed characteristic results for the five fingers. The muscular load produced by two hours of typing work was responsible mainly for the increase of total power and for the change of peak frequencies. The mechanism for the change of the power spectrum due to muscular load was well explained by the two-loop theory. It was found that the fatigue of the fingers due to muscular load could be evaluated by the total power.
Efficiency droop in III-nitride LEDs: Overview and carrier lifetime analysis (2010)

Gallium Nitride based light-emitting diodes (LEDs) are on the verge of enabling mainstream solid-state lighting. Their efficiency, however, is limited by a phenomenon known as droop which quenches internal quantum efficiency at high current density. We will review recent experimental results characterizing droop, and compare them to the various theories proposed these last years to explain this phenomenon.
Stability of Double-Row Rotator Cuff Repair Is Not Adversely Affected by Scaffold Interposition Between Tendon and Bone (2012)

Scaffolds intended for application of growth factors or cellular components in a repair situation did not adversely jeopardize the stability of the operative construct.