gebhart/patrepeval huggingface dataset:
Rectus Urethromyoplasty of Radical Prostatectomy Anastomosis Decreases Postoperative Incontinence and Anastomotic Stricture; Technique and Preliminary Results (1997)

Reinforcement of the vesico-urethral anastomosis using rectus urethromyoplasty at the time of radical prostatectomy may improve continence by increasing urethral support and mucosal coaptation. This technique may decrease the incidence of stricture formation by augmenting blood supply available for healing of the anastomosis. Rectus urethromyoplasty may be especially beneficial to patients with an increased risk of requiring adjuvant radiation therapy post-prostatectomy.
18F-FEAC and18F-FEDAC: PET of the Monkey Brain and Imaging of Translocator Protein (18 kDa) in the Infarcted Rat Brain (2010)

(18)F-FEAC and (18)F-FEDAC produced in vitro and in vivo signals allowing visualization of the increase in TSPO expression in the infarcted rat brain. The kinetics of both (18)F-ligands in the monkey brain and tolerance for in vivo metabolism suggested their usefulness for imaging studies of TSPO in primates.
Photobleaching Properties of YVO4:Eu3+ Nanophosphors Synthesized by Hydrothermal Treatment (2009)

When YVO 4 :Eu 3+ nanophosphors synthesized by a low-temperature wet chemical process in the presence of citrate ions are continuously excited by UV light, the photoluminescence (PL) intensity gradually decreases. This photobleaching is accompanied with the reduction of V 5+ to V 4+ , as confirmed by electron paramagnetic resonance spectroscopy. Hydrothermal treatment of YVO 4 :Eu 3+ nanophosphors in the presence of PO 4 3- ions produces Y(V,P)O 4 :Eu 3+ through the partial replacement between VO 4 3- and PO 4 3- , and hence results in the increase in the PL intensity and the suppression of photobleaching.
Characterization of Wavelength-Tunable Quantum Dot External Cavity Laser for 1.3-µm-Waveband Coherent Light Sources (2012)

A sandwiched sub-nano separator (SSNS) growth technique of producing high-density, high-quality InAs/InGaAs quantum dot (QD) structures on GaAs substrates is proposed. The SSNS technique achieved a density of 8.2 ×1010/cm2 by suppressing giant dot formation. The QD structures fabricated by the SSNS technique were used to form a ridge-type waveguide QD optical gain chip for O-band optical gain. With this chip, we successfully demonstrated the generation of a wavelength-tunable fine-tooth optical frequency comb in the O-band from a QD optical frequency comb laser (QD-CML), and synchronized short-optical-pulse generation (∼14 ps) with gigahertz-order repetition from a hybrid mode-locked QD-CML. We also successfully demonstrated a wavelength tunable QD-ECL with a wide wavelength tuning range (1265–1320 nm) and a narrow linewidth (210 kHz) in the O-band. It is expected that these QD coherent light sources will become attractive photonic devices for many scientific applications in the 1.0–1.3 µm waveband.
Contact angle measurement – a reliable supportive method for screening water‐resistance of ultraviolet‐protecting products in vivo (2007)

Substantivity of sunscreen formulations is affected by the wash-out rate of ultraviolet-absorber and -reflector compounds in water. Water-resistance of sunscreen formulations is currently determined according to a standardized European Cosmetic Toiletry and Perfumery Association (COLIPA) protocol, encompassing the determination of a minimal erythemal dose before and after a defined immersion step in water. It can be supposed that the higher the wettability of a treated skin area, the higher is the wash-out rate of sunscreen compounds. This present report addresses the validity of determining the wettability of treated skin alone as a measure for the water-resistance of sunscreen products. The report addresses the robustness, accuracy and congruence of a recently developed wettability test, based on the measurement of the contact angle (CA) of a sessile water drop on treated skin areas. Contact angle data of 66 sunscreen formulations are compared with the corresponding results of 81 water-resistance tests, using the sun protection factor (SPF)/immersion/SPF method. Sunscreen products tested by the CA method were applied to the skin of the volar forearm of test subjects at a defined dose and drying-time, using a standardized application and recording device. Contact angles between a sessile water drop and skin were recorded by a Charge-Coupled Device (CCD) camera and subjected to automatic contour analysis. Taking the SPF/immersion/SPF method as gold standard, accuracy parameters of the CA method were determined. By using an appropriate cut-off level of CAs, the CA method has a specificity and positive-predictive value of 100%, and turns out to be a reliable screening method to identify water-resistant formulations. Based on our findings, those formulations that give CAs above 30 degrees may be categorized water-proof without further testing by the COLIPA water-resistance method.
Optical Detection Methods in Supercritical Fluid Chromatography (1989)

A review of the current optical detection methods applicable to supercritical fluid chromatography (SFC) is presented. Performance characteristics, operational specifics, and method limitations are discussed. Ultraviolet-visible (UV-vis), fluorescence, light scattering, and chemiluminescence detectors are highlighted. The implementation in SFC and supercritical fluid extraction (SFE) of the information-rich scanning UV-vis detector is included. Scanning absorbance detectors that are based on either a photodiode array or a galvonometer-driven monochromator are discussed. Other potential nonconventional absorbance detection methods such as thermal lens calorimetry are considered.
Exploring the transcriptome of luxI - and ΔainS mutants and the impact of N-3-oxo-hexanoyl-L- and N-3-hydroxy-decanoyl-L-homoserine lactones on biofilm formation in Aliivibrio salmonicida (2018)

Background. The marine bacterium A. salmonicida uses the quorum sensing (QS) systems, AinS/R and LuxI/R to produce eight acyl-homoserine lactones (AHLs) in a cell density dependent manner . Biofilm formation is one of the QS regulated phenotypes, which requires the expression of exopolysaccharides (EPS) . We previously demonstrated that inactivation of LitR, the master regulator of QS in A. salmonicida resulted in biofilm formation, which was, similar to the biofilm formed by the AHL deficient mutant ΔainSluxI - . In this work, we have identified genes regulated by AinS and LuxI using RNA sequensing (RNA-Seq), and studied their role in biofilm formation, colony morphology and motility. We have also studied the effect of two AHLs on the biofilm formation. Results. The transcriptome profiling of ΔainS and luxI - mutants allowed us to identify essential genes regulated by QS in A. salmonicida . Relative to the wild-type, the ΔainS and luxI - mutants revealed 40 and 500 differentially expressed genes (DEGs), respectively. The functional analysis demonstrated that the most pronounced DEGs were involved in bacterial motility and chemotaxis, exopolysaccharide production, and surface structures related to adhesion. Inactivation of luxI but not ainS genes resulted in wrinkled colony morphology. While inactivation of both genes ( ΔainSluxI - ) resulted in strains able to form wrinkled colonies and mushroom structured biofilm. Moreover, when the ΔainSluxI - mutant was supplemented with N-3-oxo-hexanoyl-L- homoserine lactone (3OC6-HSL) and N-3-hydroxy-decanoyl-L-homoserine lactone(3OHC10-HSL), the biofilm did not develop. We also show that LuxI is needed for motility and repression for EPS production, where repression of EPS is likely operated through the RpoQ-sigma factor. Conclusion. These findings imply that LuxI and AinS synthases have a critical contribution to the QS-dependent regulation on gene expression and the phenotypic traits related to it.
Transmission Electron Microscopic Studies of TiSi2 Microstructures and the C49-C54 Phase Transformation in Narrow Lines (1999)

Transmission electron microscopy was used to study phase transformation of TiSi 2 from C49 to C54 phases. By the pre-amorphization implantation (PAI) treatment, the metastable C49 grain size is reduced and shows heavily defective structures. In particular, circular distributed defects surrounding a less-defective region are frequently observed for the C49 matrix. These regions are found to have mosaic structures while maintaining specific orientation. The results indicate two-dimensional growth of C49 from the less-defective region to the circular defective region. Furthermore, heterogeneous nucleation of C54 is often observed at the defective regions. This suggests local stress associated with this two-dimensional growth which enhances the heterogeneous nucleation of C54. On the contrary, strong epitaxial relationships between C49 grains and Si substrate are observed with high concentration in non-PAI samples. Since these C49 grains aligned on the substrate are considered to be stable even at relatively high temperatures, C54 nucleation sites are assumed to markedly decrease in narrow lines.
Integrated optical transmitter with micro-transfer-printed widely tunable III-V-on-Si laser (2022)

We demonstrate a C-band optical transmitter with an integrated widely-tunable III-V-on-silicon laser on the imec iSiPP50G platform using micro-transfer printing. Back-to-back operation at 40 Gbit/s non-return-to-zero On-Off keying over the C-band is presented.
Dependence of ion implantation: Induced defects on substrate doping (2001)

The characteristics of an ion implantation-induced defect in a silicon substrate are investigated. This defect is considered to be a complex of a point defect and a substrate dopant atom. The experiments are conducted by focusing on the dependence of the substrate dopant species (phosphorus and boron) on defect formation. The characteristics of the defect are investigated by measuring the bulk generation lifetime (τg) of metal–oxide–semiconductor capacitors, in which Si+ has been implanted to form the dopant-related defects in the substrate (damaging implantation) after gate oxide formation. As a result, it is found that the τg of the boron-doped substrate is one to two orders of magnitude smaller than that of the phosphorus-doped substrate for the same Nsub under the same implantation conditions. The temperature dependence of τg shows that the energy level of the defect is located at the intrinsic Fermi level, independent of the substrate dopant species and the concentration. By measuring the dependence of τg on the temperature of postdamaging implantation annealing, it is shown that the defects vanish at about 800 °C for both types of substrate. Also, it is found that the amount of dopant-related defects depends on the implantation ion species. BF2+ implantation forms more defects than As+ implantation.
Editorial: Oxaluria—The Neglected Stepchild Of Nephrolithiasis? (2003)

No AccessJournal of UrologyCLINICAL UROLOGY: Original Articles: Editorial1 Aug 2003Editorial: Oxaluria—The Neglected Stepchild Of Nephrolithiasis? Glenn M. Preminger Glenn M. PremingerGlenn M. Preminger View All Author Informationhttps://doi.org/10.1097/01.ju.0000077445.02082.3dAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Editorial: Oxaluria—The Neglected Stepchild Of Nephrolithiasis?." The Journal of Urology, 170(2), pp. 402–403 References 1 : Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N Engl J Med2002; 346: 77. Google Scholar 2 : Urinary oxalate excretion in urolithiasis and nephrocalcinosis. Arch Dis Child2000; 82: 322. Google Scholar 3 : Absence of Oxalobacter formigenes in cystic fibrosis patients: a risk factor for hyperoxaluria. Lancet1998; 352: 1026. Google Scholar 4 : Rapid reversal of hyperoxaluria in a rat model after probiotic administration of oxalobacter formigenes. J Urol2001; 166: 1487. Link, Google Scholar Comprehensive Kidney Stone Center, Duke University Medical Center, Durham, North Carolina© 2003 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 170Issue 2August 2003Page: 402-403 Advertisement Copyright & Permissions© 2003 by American Urological Association, Inc.MetricsAuthor Information Glenn M. Preminger More articles by this author Expand All Advertisement PDF downloadLoading ...
A Case of Acute Colonic Pseudoobstruction in Pregnancy (1996)

EDITORIAL COMMENT: We accepted this case for publication because it shows that acute colonic pseudoobstruction can occur during pregnancy and may be successfully managed by colonoscopy as in this patient. For readers' interest we direct them to 2 previous case reports on Ogilvie syndrome which occurred post‐Caesarean section and which were complicated by spontaneous perforation of the colon: Atypical Ogilvie syndrome. Paraskevaides EC. Aust NZ J Obstet Gynaecol 1988; 28: 148–149; Ogilvie syndrome with caecal perforation in the post‐Caesarean patient. Tang PTM, Collopy BT, Somerville M. Aust NZJ Obstet Gynaecol 1995; 35: 104–106. These papers indicate that perforation is likely to occur if the caecum is dilated to a diameter between 9–12 cm; the dilatation of the transverse colon to 18 cm in the present case is remarkable.
Background signal rejection for pO2 measurements using adaptive optics and two-photon phosphorescence lifetime microscopy (2022)

We report the implementation and demonstration of an imaging system that combines two-photon phosphorescence lifetime microscopy (2PLM) and adaptive optics for improving oxygen partial pressure (pO<sub>2</sub>) measurement accuracy in deep cortical layers of mice. The technique retrieves the background signal by forming an aberrated torus focus on the sample plane with an optical phase mask imposed on the system wavefront and subtracts it from normal phosphorescence emission signal. The proposed method is validated with intravascular pO<sub>2</sub> measurements from six mice imaged at up to ~600 &mu;m depth.
The interaction of unfused polyaromatic heterocycles with DNA: intercalation, groove-binding and bleomycin amplification. (1990)

A number of unfused-aromatic cations have been found to bind to DNA by intercalation and to amplify the bleomycin catalysed cleavage of DNA. These molecules are more similar in structure to unfused minor-groove binding compounds such as netropsin and DAPI than to fused-ring intercalators such as proflavine. An analysis of DAPI interactions with specific sequence DNA polymers has indicated that the binding modes for the molecule are sequence dependent: minor groove binding in sequences of three or more AT base pairs and intercalation in mixed or pure GC base pair sequences. As with other unfused intercalators which bind with their cationic side chains in the major groove, the amidinium groups of DAPI are in the major groove in the GC intercalation complex. DAPI is, thus, a good bleomycin amplifier in GC sequences but its minor-groove binding mode in AT sequences leads to bleomycin inhibition.
Maintaining good miRNAs in the body keeps the doctor away?: Perspectives on the relationship between food‐derived natural products and microRNAs in relation to exosomes/extracellular vesicles (2017)

During the last decade, it has been uncovered that microRNAs (miRNAs), a class of small non-coding RNAs, are related to many diseases including cancers. With an increase in reports describing the dysregulation of miRNAs in various tumor types, it has become abundantly clear that miRNAs play significant roles in the formation and progression of cancers. Intriguingly, miRNAs are present in body fluids because they are packed in exosomes/extracellular vesicles and released from all types of cells. The miRNAs in the fluids are measured in a relatively simple way and the profile of miRNAs is likely to be an indicator of health condition. In recent years, various studies have demonstrated that some naturally occurring compounds can control tumor-suppressive and oncogenic miRNAs in a positive manner, suggesting that food-derived compounds could maintain the expression levels of miRNAs and help maintain good health. Therefore, our daily food and compounds in food are of great interest. In addition, exogenous diet-derived miRNAs have been indicated to function in the regulation of target mammalian transcripts in the body. These findings highlight the possibility of diet for good health through the regulation of miRNAs, and we also discuss the perspective of food application and health promotion.
Design of New Derivatives of Nitrone DEPMPO Functionalized at C-4 for Further Specific Applications in Superoxide Radical Detection (2007)

A general synthetic route to prepare derivatives of the DEPMPO nitrone (5-diethoxyphosphoryl-5-methyl-1-pyrroline-N-oxide) functionalized at C-4 was established via the synthesis of 4-HMDEPMPO nitrone (5-diethoxyphosphoryl-4-hydroxymethyl-5-methyl-1-pyrroline-N-oxide) that was obtained from reduction of the nitro compound 1. (4R*,5S*)-4-HMDEPMPO was successfully separated from its minor diastereoisomer and could be used to generate various substituted analogues. Among them, 4-NHSDEPMPO, 5-diethoxyphosphoryl-4-succinimidyloxycarbonyloxymethyl-5-methyl-1-pyrroline-N-oxide, constitutes a NH2-reactive precursor for further conjugation to relevant moieties such as targeting groups, labels, or drugs. From 4-NHSDEPMPO, a biotinylated nitrone was synthesized offering new perspectives for targeted delivery applications. A short study of the trapping behaviors of the (4R*,5S*)-isomer of these 4-HMDEPMPO analogues proved that they are as good as DEPMPO for detecting superoxide. For each isomer, only one diastereoisomer adduct was obtained, resulting from the addition of superoxide on the less hindered face of the nitrone, that is, trans to the phosphoryl group and the C-4 substituent. From spectra simulation and experiments in various solvents, we proved that ESR patterns of each adduct corresponded to the superimposed signals of two sets of conformers in a sufficiently slow chemical exchange to induce a widening and a dissymmetry of some of the signal lines. This phenomenon was drastically reduced when compared with that observed for DEPMPO superoxide and attributed to a similar chemical exchange, and it did not hamper spectrum assignment. Determination of the decay rate of the superoxide adduct of (4R*,5S*)-4-HMDEPMPO proved that it has a 25% longer half-life time than the superoxide adduct of DEPMPO.
Solvent Effects on the Phosphorescence of Gold(III) Complexes Chelated by β-Multisubstituted Corroles (2021)

A set of gold corrole complexes containing four different β-substituent groups (Br/I/CF<sub>3</sub>), namely, <b>4Br-Au</b>, <b>4I-Au</b>, and <b>4CF</b><sub><b>3</b></sub><b>-Au</b>, were investigated; all showed room temperature phosphorescence. The phosphorescence quantum yields of the corroles were determined using tetraphenylporphyrin as a reference: Φ<sub>ph</sub> (<b>4I-Au</b>, 0.75%) > Φ<sub>ph</sub> (<b>4Br-Au</b>, 0.64%) > Φ<sub>ph</sub> (<b>4CF</b><sub><b>3</b></sub><b>-Au</b>, 0.38%). <b>4CF</b><sub><b>3</b></sub><b>-Au</b> exhibited near-IR emission (858 nm, aerobic); absorbance intensity for the Q-band was higher than that for the Soret band. Complex <b>4I-Au</b> showed a longer phosphorescence lifetime (82 μs) compared to those of <b>4Br-Au</b> (53 μs) and <b>4CF</b><sub><b>3</b></sub><b>-Au</b> (28 μs; N<sub>2</sub>, tol). Thermally activated delayed fluorescence (TADF) emission of <b>4I/Br-Au</b> complexes was observed: stronger emission intensity correlated with increasing temperature. Good negative correlations for <b>4I/Br-Au</b> were observed between the Soret band absorption energy and the solvent polarizability: excited states of <b>4I/Br-Au</b> are more polar than their ground states. TD-DFT calculations revealed very fast intersystem crossing (ISC) rate constants, 2.20 × 10<sup>12</sup> s<sup>-1</sup> (<b>4CF</b><sub><b>3</b></sub><b>-Au</b>) > 1.96 × 10<sup>11</sup> s<sup>-1</sup> (<b>4Br-Au</b>) > 1.15 × 10<sup>11</sup> s<sup>-1</sup> (<b>4I-Au</b>), and importantly, the reverse intersystem crossing (rISC) rate constants are determined as 1.68 × 10<sup>7</sup> s<sup>-1</sup> (<b>4I-Au</b>) > 2.40 × 10<sup>3</sup> s<sup>-1</sup> (<b>4Br-Au</b>) ≫ 8.09 × 10<sup>-8</sup> s<sup>-1</sup> (<b>4CF</b><sub><b>3</b></sub><b>-Au</b>). The exceptionally low rISC rate constant of <b>4CF</b><sub><b>3</b></sub><b>-Au</b> is attributed to its more steric and deformed structure bearing a larger energy gap between the S<sub>1</sub> and T<sub>1</sub> states.
Local volume fraction fluctuations in random media (1997)

Although the volume fraction is a constant for a statistically homogeneous random medium, on a spatially local level it fluctuates. We study the full distribution of volume fraction within an observation window of finite size for models of random media. A formula due to Lu and Torquato for the standard deviation or “coarseness’’ associated with the local volume fraction ξ is extended for the nth moment of ξ for any n. The distribution function FL of the local volume fraction of five different model microstructures is evaluated using analytical and computer-simulation methods for a wide range of window sizes and overall volume fractions. On the line, we examine a system of fully penetrable rods and a system of totally impenetrable rods formed by random sequential addition (RSA). In the plane, we study RSA totally impenetrable disks and fully penetrable aligned squares. In three dimensions, we study fully penetrable aligned cubes. In the case of fully penetrable rods, we will also simplify and numerically invert a prior analytical result for the Laplace transform of FL. In all of these models, we show that, for sufficiently large window sizes, FL can be reasonably approximated by the normal distribution.
Femtosecond pulse timing measurement using an ultrafast organic molecular film and a computational sensor array (2004)

We demonstrate a precision pulse timing measurement technique using a molecular film of squarylium dye J-aggregate and a high-bandwidth computational sensor array to achieve high-density, parallel extraction of femtosecond optical pulses.
The in vitro effect of commercially available noble metal nanocolloids on the rainbow trout (Oncorhynchus mykiss) leukocyte and splenocyte activity (2013)

The growing popularity of nanotechnology in the past decade has increased nanomaterial concentrations in the environment and the risk of their toxicity for aquatic organisms. Metal nanoparticles, which are easily absorbed and accumulated by fish, are probably able to interact directly with their immunocompetent cells. The objective of this study was to evaluate the in vitro effect of commercially available silver, gold and copper nanocolloids on the rainbow trout leukocyte and splenocyte activity. At high concentrations, all of the nanocolloids studied had adverse effects on the proliferative response of trout lymphocytes, and the most toxic of them, silver, decreased also the respiratory burst activity of splenocytes. Low concentrations of silver nanocolloid, however, had a stimulating effect on the lymhocyte proliferation.