gebhart/patrepeval huggingface dataset:
Reconstruction-Based Disentanglement for Pose-Invariant Face Recognition (2017)

Deep neural networks (DNNs) trained on large-scale datasets have recently achieved impressive improvements in face recognition. But a persistent challenge remains to develop methods capable of handling large pose variations that are relatively under-represented in training data. This paper presents a method for learning a feature representation that is invariant to pose, without requiring extensive pose coverage in training data. We first propose to generate non-frontal views from a single frontal face, in order to increase the diversity of training data while preserving accurate facial details that are critical for identity discrimination. Our next contribution is to seek a rich embedding that encodes identity features, as well as non-identity ones such as pose and landmark locations. Finally, we propose a new feature reconstruction metric learning to explicitly disentangle identity and pose, by demanding alignment between the feature reconstructions through various combinations of identity and pose features, which is obtained from two images of the same subject. Experiments on both controlled and in-the-wild face datasets, such as MultiPIE, 300WLP and the profile view database CFP, show that our method consistently outperforms the state-of-the-art, especially on images with large head pose variations.
Systemically Administered IgG Anti-Toxin Antibodies Protect the Colonic Mucosa during Infection with Clostridium difficile in the Piglet Model (2014)

The use of anti-toxin human monoclonal antibodies (HMab) as treatment for C. difficile infection has been investigated in animal models and human clinical trials as an alternative to or in combination with traditional antibiotic therapy. While HMab therapy appears to be a promising option, how systemically administered IgG antibodies protect the colonic mucosa during Clostridium difficile infection is unknown. Using the gnotobiotic piglet model of Clostridium difficile infection, we administered a mixture of anti-TcdA and anti-TcdB HMabs systemically to piglets infected with either pathogenic or non-pathogenic C. difficile strains. The HMabs were present throughout the small and large intestinal tissue of both groups, but significant HMabs were present in the lumen of the large intestines only in the pathogenic strain-infected group. Similarly, HMabs measured in the large intestine over a period of 2-4 days following antibody administration were not significantly different over time in the gut mucosa among the groups, but concentrations in the lumen of the large intestine were again consistently higher in the pathogenic strain-infected group. These results indicate that systemically administered HMab IgG reaches the gut mucosa during the course of CDI, protecting the host against systemic intoxication, and that leakage through the damaged colon likely protects the mucosa from further damage, allowing initiation of repair and recovery.
Carbon Nanotube Immobilized Composite Hollow Fiber Membranes for Pervaporative Removal of Volatile Organics from Water (2010)

This paper reports the development of novel carbon nanotube immobilized composite membranes (CNIM) for pervaporative removal of organics from an aqueous matrix. The nanotubes were immobilized into the pores of a composite, where they served as sorption sites that provided additional pathways for enhanced solute transport, affecting both the partitioning and diffusion through the membrane. Depending upon the process conditions, the enhancement in organic removal and mass transfer rates were higher by 108 and 95%, respectively. The CNIM demonstrated several advantages including enhanced recovery at low concentrations, lower temperatures, and higher flow rates. Overall, these lead to more energy efficient processes.
One-Day Ex Vivo Culture Allows Effective Gene Transfer Into Human Nonobese Diabetic/Severe Combined Immune-Deficient Repopulating Cells Using High-Titer Vesicular Stomatitis Virus G Protein Pseudotyped Retrovirus (1999)

Retrovirus-mediated gene transfer into long-lived human pluripotent hematopoietic stem cells (HSCs) is a widely sought but elusive goal. A major problem is the quiescent nature of most HSCs, with the perceived requirement for ex vivo prestimulation in cytokines to induce stem cell cycling and allow stable gene integration. However, ex vivo culture may impair stem cell function, and could explain the disappointing clinical results in many current gene transfer trials. To address this possibility, we examined the ex vivo survival of nonobese diabetic/severe combined immune-deficient (NOD/SCID) repopulating cells (SRCs) over 3 days. After 1 day of culture, the SRC number and proliferation declined twofold, and was further reduced by day 3; self-renewal was only detectable in noncultured cells. To determine if the period of ex vivo culture could be shortened, we used a vesicular stomatitis virus G protein (VSV-G) pseudotyped retrovirus vector that was concentrated to high titer. The results showed that gene transfer rates were similar without or with 48 hours prestimulation. Thus, the use of high-titer VSV-G pseudotyped retrovirus may minimize the loss of HSCs during culture, because efficient gene transfer can be obtained without the need for extended ex vivo culture.
Retinopathy and Risk of Congestive Heart Failure (2005)

Retinopathy is an independent predictor of CHF, even in persons without preexisting coronary heart disease, diabetes, or hypertension. This suggests that microvascular disease may play an important role in the development of heart failure in the general population. Some asymptomatic persons with retinopathy on an ophthalmologic examination may benefit from further assessment of CHF risk.
Crucial Role of the HIGH-loop Lysine for the Catalytic Activity of Arginyl-tRNA Synthetase (2001)

The presence of two short signature sequence motifs (His-Ile-Gly-His (HIGH) and Lys-Met-Ser-Lys (KMSK)) is a characteristic of the class I aminoacyl-tRNA synthetases. These motifs constitute a portion of the catalytic site in three dimensions and play an important role in catalysis. In particular, the second lysine of the KMSK motif (K2) is the crucial catalytic residue for stabilization of the transition state of the amino acid activation reaction (aminoacyl-adenylate formation). Arginyl-tRNA synthetase (ArgRS) is unique among all of the class I enyzmes, as the majority of ArgRS species lack canonical KMSK sequences. Thus, the mechanism by which this group of ArgRSs achieves the catalytic reaction is not well understood. Using three-dimensional modeling in combination with sequence analysis and site-directed mutagenesis, we found a conserved lysine in the KMSK-lacking ArgRSs upstream of the HIGH sequence motif, which is likely to be a functional counterpart of the canonical class I K2 lysine. The results suggest a plausible partition of the ArgRSs into two major groups, on the basis of the conservation of the HIGH lysine.
Characterization of Printer MTF (2006)

We develop a comprehensive procedure for characterizing the modulation transfer function (MTF) of a digital printer. Especially designed test pages consisting of a series of patches, each with a different one-dimensional (1D) sinusoidal modulation, enable measurement of the dependence of the MTF on spatial frequency, bias point, modulation amplitude, spatial direction of modulation, and direction of modulation in the color space. Constant tone patches also yield the extreme and center color values for the input modulation. After calibrating the scanner specifically for the direction of modulation in the color space, we spatially project the scanned test patches in the direction orthogonal to the modulation to obtain a 1D signal, and then project these sample points onto a line in the CIE L*a*b* color space between the extreme color values to obtain a perceptually relevant measure of the frequency response in a specific color direction. Appropriate normalization of the frequency response followed by compensation for the scanner MTF completes the procedure. For a specific inkjet printer using a dispersed-dot halftoning algorithm, we examine the impact of the above-mentioned parameters on the printer MTF, and obtain results that are consistent with the expected behavior of this combination of print mechanism and halftoning algorithm.
Occupational rhinoconjunctivitis and asthma caused by Tetranychus urticae (red spider mite). A case report (1994)

Abstract. This paper highlights a clinical case of a patient suffering bronchial asthma and rhinoconjunctivitis due to sensitization to Tetranychus urticae(TU ), commonly known as the red spider mite, which belongs to the Prostigmata sub‐order of the Tetranychidae family, in relation to a work environment (a carnation nursery). Both prick and intradermal skin tests were positive, as well as specific bronchial challenge tests with TU extract. Specific IgE was demonstrated by RAST (Class 3). Unspecific bronchial provocation with methacholine was negative. Sodium dodecylsulfate‐polyacrylamide gel elcctrophoresis (SDS‐PAGE) immunoblotting revealed the presence of seven main IgE binding proteins, the more intense bands being those appearing at 21. 17 and 15 kDa. This indicates a case of immediated type hypersensitivity to Tetranychus urticae with a clear correlation to occupational environment.
An Active Flow Control Approach for Spatially Growing Mixing Layer (2022)

Abstract A control approach is proposed in this study that controls the growth of a spatially growing mixing layer in an open loop. Due to the similarity of the mixing layer dynamics in the temporal and spatial domains, the control is exercised in the temporal domain that leads to optimization of the layer in the spatial domain. The proportional-integral-derivative (PID) control in the temporal domain uses Navier–Stokes equations as the plant model. Apart from being prohibitively expensive, control in the spatial domain presents convective time delay problems. These barriers are circumvented by solving the control problem in the temporal domain very rapidly, based on a given set point in the linear regime. Once the set point in the temporal domain is reached, the corresponding initial conditions in the temporal domain are mapped to inflow boundary conditions in the spatial domain. With these mapped inflow boundary conditions in the spatial domain, the spatial development of the mixing layer is followed, which confirms the efficacy of control in the spatial domain. The present control methodology offers a new paradigm for control of the spatially growing mixing layer.
ChemInform Abstract: Enantiospecific Synthesis of (‐)‐Alstonerine and (+)‐Macroline as Well as a Partial Synthesis of (+)‐Villalstonine. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Overcoming cardiac allograft vasculopathy (CAV) by inducing tolerance (2002)

There is compelling evidence that MHC-driven immune processes play a dominant role in the development of cardiac allograft vasculopathy. Thus, it makes intuitive sense that tolerance, which eliminates donor alloreactivity, should protect against CAV. However, in the experimental literature, there are examples of CAV occurring in recipients rendered tolerant by either peripheral or central induction protocols. Why does transplant arteriopathy occur in recipients that have achieved a robust state of tolerance or in the animals devoid of T or B cell immunity? There may be immunological blindspots that persist even after a state of tolerance is achieved. These blindspots could contribute to the pathogenesis of chronic rejection (CR).
Improvement of Crystalline Quality in GaN Films by Air-Bridged Lateral Epitaxial Growth (2000)

Air-bridged lateral epitaxial growth (ABLEG), a new technique of lateral growth of GaN films, has been developed using low-pressure metalorganic vapor phase epitaxy. A previously grown 1-µm-thick GaN film is grooved along the &lt;1\bar100 &gt; GaN direction, and the bottoms of the trenches and the sidewalls are covered with a silicon nitride mask. A free-standing GaN material is regrown from the exposed (0001) surface of the ridged GaN seed structure. Cross-sectional transmission electron microscopy analysis reveals that the dislocations originating from the underlying seed GaN extend straight in the &lt;0001 &gt; direction and dislocations do not propagate into the wing region. The wing region also exhibits a smooth surface and the root mean square roughness is found to be 0.088 nm by atomic force microscopy measurement of the (0001) face of the wing region.
Torque fluctuation and critical clearing time in wind power generation by induction machines (2006)

Squirrel cage induction machines represent a common solution widely adopted in wind generation. The induction machine is simple, reliable, cheap and requires very little maintenance. Some problems are, however, connected with the use of induction machines in wind power generation systems. In particular two effects have to be taken into account: the torque fluctuations at the generator shaft and the critical clearing time (CCT). Both problems represent a serious limitation for weak networks in which the first effect can cause flicker effect while the CCT is very short. In the paper a full modelling of a wind energy plant constituted by n machines is presented. Using the set-up model the behaviour of the plant for a different number of connected machines is analysed. In particular, the system stability connected with voltage sags and network faults is studied.
Home-Assistant Robot for an Aging Society (2012)

Many countries around the world face three major issues associated with their aging societies: a declining population, an increasing proportion of seniors, and an increasing number of single-person households. To explore assistive technologies that can help solve the problems faced by aging societies, we have tested several information and robot technologies. This paper introduces research on a home-assistant robot, which improves the ease and productivity of home activities. For people who work hard outside the home, the assistant robot performs chores in their home environment while they are away. A case study of a life-sized robot with a humanlike functional body performing daily chores is presented. An integrated software system incorporating modeling, recognition, and manipulation skills, as well as a motion generation approach based on the software system, is explained. Moreover, because housekeepers perform chores one after another in their daily environment, we also aim to develop a system for continuously performing a series of tasks by including failure detection and recovery.
Xpert MTB/RIF Assay Shows Faster Clearance of Mycobacterium tuberculosis DNA with Higher Levels of Rifapentine Exposure (2016)

The Xpert MTB/RIF assay is both sensitive and specific as a diagnostic test. Xpert also reports quantitative output in cycle threshold (C<sub>T</sub>) values, which may provide a dynamic measure of sputum bacillary burden when used longitudinally. We evaluated the relationship between Xpert C<sub>T</sub> trajectory and drug exposure during tuberculosis (TB) treatment to assess the potential utility of Xpert C<sub>T</sub> for treatment monitoring. We obtained serial sputum samples from patients with smear-positive pulmonary TB who were consecutively enrolled at 10 international clinical trial sites participating in study 29X, a CDC-sponsored Tuberculosis Trials Consortium study evaluating the tolerability, safety, and antimicrobial activity of rifapentine at daily doses of up to 20 mg/kg of body weight. Xpert was performed at weeks 0, 2, 4, 6, 8, and 12. Longitudinal C<sub>T</sub> data were modeled using a nonlinear mixed effects model in relation to rifapentine exposure (area under the concentration-time curve [AUC]). The rate of change of C<sub>T</sub> was higher in subjects receiving rifapentine than in subjects receiving standard-dose rifampin. Moreover, rifapentine exposure, but not assigned dose, was significantly associated with rate of change in C<sub>T</sub> (P = 0.02). The estimated increase in C<sub>T</sub> slope for every additional 100 μg · h/ml of rifapentine drug exposure (as measured by AUC) was 0.11 C<sub>T</sub>/week (95% confidence interval [CI], 0.05 to 0.17). Increasing rifapentine exposure is associated with a higher rate of change of Xpert C<sub>T</sub>, indicating faster clearance of Mycobacterium tuberculosis DNA. These data suggest that the quantitative outputs of the Xpert MTB/RIF assay may be useful as a dynamic measure of TB treatment response.
Data from The Antitumor Efficacy of IL2/IL21-Cultured Polyfunctional Neu-Specific T Cells Is TNFα/IL17 Dependent (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Infusion of HER2-specific T cells, derived from vaccine-primed patients and expanded with IL2/IL12, has induced tumor regression in a minority of patients with metastatic treatment-refractory HER2&lt;sup&gt;+&lt;/sup&gt; breast cancer. We questioned whether alteration of cytokine growth factors used to culture vaccine–primed T cells could improve antitumor activity.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; Using the TgMMTV-neu murine mammary tumor model, we cultured T cells derived from mice immunized with a previously defined neu class II peptide, p98-114 (neu p98), and evaluated different cytokine combinations for expansion.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; Infusion of neu p98-specific T-cell lines derived from all cytokine conditions evaluated resulted in significant antitumor activity compared with infused naïve splenocytes (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). T cells cultured with IL2/IL21 could uniquely mediate complete regression of spontaneous mammary tumors. IL2/IL21 cultured neu-specific T cells demonstrated a different cytokine secretion pattern as compared with other cultured T cells; secreting high levels of TNFα and IL17 (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). Moreover, tumor-infiltrating CD8&lt;sup&gt;+&lt;/sup&gt; cells were significantly increased after the infusion of IL2/IL21 cultured T cells as compared with tumors treated with T cells expanded under other cytokine conditions (&lt;i&gt;P&lt;/i&gt; &lt; 0.001). The antitumor effect of the infusion of IL2/IL21 cultured cells was mediated by CD8 T cells. Depletion of TNFα or IL17, but not IFNγ, abrogated the tumor growth inhibition induced by the IL2/IL21 T cells and markedly decreased the influx of CD8 into tumors. Finally, IL2/IL21-cultured human antigen specific T cells also displayed a similar polyfunctional Th1/Th17 phenotype.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Expansion of HER2 vaccine–primed T cells with IL2/IL21 may have the potential to effectively mediate tumor regression when used in adoptive transfer. &lt;i&gt;Clin Cancer Res; 22(9); 2207–16. ©2015 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Implications of industry template adoption at 10 and 7nm (2015)

A novel technique for optimally determining a limited set of layout patterns called templates accounts for circuit needs and navigates sources of process variability with no power, performance, or area penalty.
Screening for Nitric Oxide-Dependent Protein-Protein Interactions (2003)

Because nitric oxide (NO) may be a ubiquitous regulator of cellular signaling, we have modified the yeast two-hybrid system to explore the possibility of NO-dependent protein-protein interactions. We screened for binding partners of procaspase-3, a protein implicated in apoptotic signaling pathways, and identified multiple NO-dependent interactions.Two such interactions, with acid sphingomyelinase and NO synthase, were shown to occur in mammalian cells dependent on endogenous NO. Nitrosylation may thus provide a broad-based mechanism for regulating interactions between proteins. If so, systematic proteomic analyses in which redox state and NO bioavailability are carefully controlled will reveal a large array of novel interactions.
제주도 농촌지역 주민의 벌독 알레르기 유병율 (1998)

Backpwnd: Prevalence of bee venom allergy in Korea is unknown, Objective'. We performed a cross-sectional study to evaluate the prevalence of bee venom allergy and importance of risk factors, such as age, sex, and atopy, in the development of the allergic reaction in children and adults living in rural area of Cheju Island. Swbject and method: The prevalence was investigated in subjects with 1,054 children and 370 adults (701 male, 723 female), aged 7-87 years, living in rural area of Cheju Island. A history particularly focused on the systemic reactions after the bee stings was taken in all subjects. Skin prick test,s to common inhalant allergens, including house dust mites, fungi, tree, grass, mugwort and ragweed pollen, cockroach, animal epithelium, Japanese cedar pollen, and citrus red mite were performed. Result: The prevalence of bee venom allergy was 5.8% (mild systemic reactions 5.0%, severe systemic reactions 0.8% ). The prevalence was higher in adults than in children (10.2% vs. 5.0%, g = 12.0, p 0.05). The prevalence of bee venom allergy was not significantly different between subjects with positive skin reaction and those with negative skin reaction to inhalant allergens (6.4% vs. 5.4% ), Conclasion'. The prevlence of bee venom allergy in inhabitants of rural area of Cheju Island is 5.8% (mild systemic,' 5.0%, severe systemic reaction. 0.8%), and bee venom allergy was more common in adults than in children, and in male children than in female children.
An unsaturated peptidomimetic assembly derived from a carbohydrate (2003)

A strategy has been established for the synthesis of peptidomimetics derived from unsaturated carbohydrates, and exemplified by the use of methyl 2,6-anhydro-7-azido-3,7-deoxy-4,5-O-isopropylidene-D-lyxo-hept-2-enonate 9 as a dipeptide 'monomer' which can be elaborated from either end. Selective reduction of 9 gives a protected pseudodipeptide ester suitable for use as an amino component, and saponification gives an azido acid suitable for use as a carboxyl component. The 'dimer' product of coupling these two components with TBTU can be similarly elaborated at either end to give a 'trimer' and a further cycle of selective reduction and coupling gave a 'tetramer', 17, a pseudo-octapeptide.
Updates for RSAES-OAEP and RSASSA-PSS Algorithm Parameters (2010)

This document updates RFC 4055. It updates the conventions for using
the RSA Encryption Scheme - Optimal Asymmetric Encryption Padding
(RSAES-OAEP) key transport algorithm in the Internet X.509 Public Key
Infrastructure (PKI). Specifically, it updates the conventions for
algorithm parameters in an X.509 certificate's subjectPublicKeyInfo
field. [STANDARDS-TRACK]
Study protocol: PoPE-Prediction of Preterm delivery by Electrohysterography (2014)

Current Controlled Trials ISRCTN07603227.
Imaging the Sunyaev Zel'dovich effect from the South Pole with the ACBAR instrument on Viper Telescope (2002)

We will present maps of low redshift Abell clusters made with two instruments, Corona (40 GHz) and ACBAR (150, 210, 275 GHz), that have operated on the Viper telescope at the South Pole. We will describe an attempt to measure Hubble's Constant from a Corona map of A3667 and discuss how this measurement has been hampered by contamination from primary CMB anisotropies. The availability of multi-frequency data from ACBAR has allowed us to subtract the CMB signal and to produce resolved Sunyaev-Zeldovich (SZ) images of A3667 and A3226. We will compare the SZ images of these clusters to weak lensing data and to X-ray data from the ROSAT, ASCA, Chandra and XMM satellites. This work has been supported in part by a NASA LTSA grant; NAG5-7926.