gebhart/patrepeval huggingface dataset:
Electro/thermal measurements of RF MEMS capacitive switches (2003)

An aspect-ratio-limited fabrication procedure for the secondary handling of miniaturized micromachined and fiber-fed gallium arsenide electrothermal probes is presented, and a completed probe is used to measure the electric field and temperature above an RF MEMS capacitive switch. The probe dimensions are 125 /spl mu/m /spl times/ 125 /spl mu/m /spl times/ 100 /spl mu/m. Measurements of switches with dimensions of 250 /spl mu/m /spl times/ 640 /spl mu/m are performed for RF powers between 252 mW and 6.7 W in the UP and DOWN states. Non-contact temperature measurements 25 /spl mu/m above the switch in the UP state show a thermal rise time of 0.63 /spl plusmn/ 0.05 seconds for an RF input power of 6.7 W. The accompanying temperature rise is 16.8 /spl plusmn/ 0.7/spl deg/C. In the DOWN state, the increase in temperature is 3.0 /spl plusmn/ 0.8/spl deg/C. Spatial line scans of temperature show the localization of heat energy in the UP state and its delocalization in the DOWN state due to conductive heat transfer into the substrate. Electric field measurements yield traveling waves in the UP state and standing waves in the down state. Standing waves in the DOWN state are consistent with preferential substrate heating on the input side to the switch.
Broadband branch-line coupler with very loose coupling utilizing open/short-circuited coupled-transmission lines (2014)

In this paper broadband branch-line couplers with loose couplings (less than -10 dB) utilizing open/short-circuited coupled-transmission lines are proposed. By applying the equivalent admittance approach to the proposed branch-line coupler, broadband characteristics with a relative bandwidth of 47.5% for 20 dB return loss and directivity can be obtained in the case of the branch-line coupler with a coupling factor of -20 dB. The validity of this design procedure has been demonstrated by electromagnetic simulations and experiments.
Device Performance Evaluation of PMOS Devices Fabricated by B>inf<2>/inf<H>inf<6>/inf<PIII/PLAD Process on Poly-Si Gate Doping (2006)

It has been shown that the PIII/PLAD poly-Si gate doping process offers unique advantages over conventional beam line systems, including system simplification, lower cost, higher throughput, and device performance equivalence or improvement. PMOS devices fabricated by a B <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> H <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</inf> /H <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> PIII/PLAD process on P <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> poly-gate doping are intensively evaluated in this paper. In addition to higher throughput, PMOS devices fabricated by a PLAD process showed an equivalent electrical performance to those fabricated by conventional beam line ion implantation, including similar poly-Si gate resistance and depletion, threshold and sub-threshold characteristics, drive current, and gate-oxide integrity.
Phase modeling based on the α-factor in bulk semiconductor optical amplifiers (2003)

Different approaches based on the α-factor to model the phase of the optical fields in bulk semiconductor optical amplifiers are analyzed. Our time-domain numerical model is presented and it is calibrated by means of experimental characterizations of the device gain, of the amplified spontaneous emission spectra, and of the effective α-factor. We then compare the phase modulation at the SOA output for three cases. In the first one, the α-factor is always taken as constant. In the second case, the α-factor is set according to the SOA working point and then kept fixed. In the last case, we take into account the dependence of the α-factor on the carrier density and on the wavelength for every simulated time step. We shall identify when the first two approximations listed above deliver reliable results. In particular cases, the use of a constant value for the α-factor can lead to phase errors up to 50%.
ChemInform Abstract: Synthesis of 5′‐O‐Phosphonomethyl Derivatives of Pyrimidine 2′‐ Deoxynucleosides. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Determination of Fracture Toughness of Thermally Conductive Adhesives (1997)

Technical Papers Determination of Fracture Toughness of Thermally Conductive Adhesives E. Jih, E. Jih Ford Research Laboratory, Ford Motor Company, Dearborn, MI 48121-2053 Search for other works by this author on: This Site PubMed Google Scholar Y.-H. Pao, Y.-H. Pao Ford Research Laboratory, Ford Motor Company, Dearborn, MI 48121-2053 Search for other works by this author on: This Site PubMed Google Scholar X. Song, X. Song Optimal CAE Inc., Novi, MI 48375 Search for other works by this author on: This Site PubMed Google Scholar C. Larner C. Larner Automotive Components Division, Ford Motor Company, Dearborn, MI 48121-2053 Search for other works by this author on: This Site PubMed Google Scholar Author and Article Information E. Jih Ford Research Laboratory, Ford Motor Company, Dearborn, MI 48121-2053 Y.-H. Pao Ford Research Laboratory, Ford Motor Company, Dearborn, MI 48121-2053 X. Song Optimal CAE Inc., Novi, MI 48375 C. Larner Automotive Components Division, Ford Motor Company, Dearborn, MI 48121-2053 J. Electron. Packag. Sep 1997, 119(3): 204-207 (4 pages) https://doi.org/10.1115/1.2792235 Published Online: September 1, 1997 Article history Received: July 15, 1996 Revised: March 1, 1997 Online: November 6, 2007
Computerized polymorphic marker identification: Experimental validation and a predicted human polymorphism catalog (1998)

A computational system for the prediction of polymorphic loci directly and efficiently from human genomic sequence was developed and verified. A suite of programs, collectively called POMPOUS (polymorphic marker prediction of ubiquitous simple sequences) detects tandem repeats ranging from dinucleotides up to 250 mers, scores them according to predicted level of polymorphism, and designs appropriate flanking primers for PCR amplification. This approach was validated on an approximately 750-kilobase region of human chromosome 3p21.3, involved in lung and breast carcinoma homozygous deletions. Target DNA from 36 paired B lymphoblastoid and lung cancer lines was amplified and allelotyped for 33 loci predicted by POMPOUS to be variable in repeat size. We found that among those 36 predominately Caucasian individuals 22 of the 33 (67%) predicted loci were polymorphic with an average heterozygosity of 0.42. Allele loss in this region was found in 27/36 (75%) of the tumor lines using these markers. POMPOUS provides the genetic researcher with an additional tool for the rapid and efficient identification of polymorphic markers, and through a World Wide Web site, investigators can use POMPOUS to identify polymorphic markers for their research. A catalog of 13,261 potential polymorphic markers and associated primer sets has been created from the analysis of 141,779,504 base pairs of human genomic sequence in GenBank. This data is available on our Web site (pompous.swmed.edu) and will be updated periodically as GenBank is expanded and algorithm accuracy is improved.
Disruption and Formation of Surface Salt Bridges Are Coupled to DNA Binding by the Integration Host Factor: A Computational Analysis (2010)

Revealing the thermodynamic driving force of protein-DNA interactions is crucial to the understanding of factors that dictate the properties and function of protein-DNA complexes. For the binding of DNA to DNA-wrapping proteins, such as the integration host factor (IHF), Record and co-workers proposed that the disruption of a large number of preexisting salt bridges is coupled with the binding process [Holbrook, J. A., et al. (2001) J. Mol. Biol. 310, 379]. To test this proposal, we have conducted explicit solvent MD simulations (multiple ∼25-50 ns trajectories for each salt concentration) to examine the behavior of charged residues in IHF, especially concerning their ability to form salt bridges at different salt concentrations. Of the 17 cationic residues noted by Record and co-workers, most are engaged in salt bridge interactions for a significant portion of the trajectories, especially in the absence of salt. This observation suggests that, from a structural point of view, their proposal is plausible. However, the complex behaviors of charged residues observed in the MD simulations also suggest that the unusual thermodynamic characteristics of IHF-DNA binding likely arise from the interplay between complex dynamics of charged residues both in and beyond the DNA binding site. Moreover, a comparison of MD simulations at different salt concentrations suggests that the strong dependence of the IHF-DNA binding enthalpy on salt concentration may not be due to a significant decrease in the number of stable salt bridges in apo IHF at high salt concentrations. In addition to the Hofmeister effects quantified in more recent studies of IHF-DNA binding, we recommend consideration of the variation of the enthalpy change of salt bridge disruption at different salt concentrations. Finally, the simulation study presented here explicitly highlights the fact that the electrostatic properties of DNA-binding proteins can be rather different in the apo and DNA-bound states, which has important implications for the design of robust methods for predicting DNA binding sites in proteins.
Comparison of voltage and current testing of analogue and mixed-signal circuits (2002)

The author presents a time-domain testing technique for analogue and mixed-signal circuits. The circuit-under-test (CUT) is simulated by a pseudo-random-binary sequence (PRBS) signal and both the voltage and supply current (Iddq) responses are measured. Both measurements are subsequently analyzed to detect the presence of a fault and to establish which measurement achieves higher confidence in the detection. The technique can test mixed-signal circuits in a unified manner and detecting soft and catastrophic faults.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Discovery of WAY-260022, a Potent and Selective Inhibitor of the Norepinephrine Transporter (2010)

The potency and selectivity of a series of 1-{(1S)-2-[amino]-1-[3-(trifluoromethoxy)phenyl]ethyl}cyclohexanol analogues are described. These compounds were prepared to improve in vitro metabolic stability and achieve brain penetration. Compound 13 (WAY-260022, NRI-022) was found to be a potent inhibitor of norepinephrine reuptake and demonstrated excellent selectivity over the serotonin and dopamine transporters. Additionally, 13 exhibited oral efficacy in a rat model of thermoregulatory dysfunction.
History and current status of strontium iodide scintillators (2017)

Eu-doped strontium iodide single crystal growth has reached maturity and prototype SrI<sub>2</sub>(Eu)-based gamma ray spectrometers provide detection performance advantages over standard detectors. SrI<sub>2</sub>(Eu) offers a high, proportional light yield of &gt;80,000 photons/MeV. Energy resolution of &lt;3% at 662 keV with 1.5” x 1.5” SrI<sub>2</sub>(Eu) crystals is routinely achieved, by employing either a small taper at the top of the crystal or a digital readout technique. These methods overcome light-trapping, in which scintillation light is re-absorbed and re-emitted in Eu<sup>2+</sup>-doped crystals. Its excellent energy resolution, lack of intrinsic radioactivity or toxicity, and commercial availability make SrI2(Eu) the ideal scintillator for use in handheld radioisotope identification devices. A 6-lb SrI<sub>2</sub>(Eu) radioisotope identifier is described.
Influence of substituted tetrahydroisoquinolines on lipolysis, in vitro (1970)

Journal Article Influence of substituted tetrahydroisoquinolines on lipolysis, in vitro Get access D R Feller, D R Feller Divisions of Pharmacology and Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA Search for other works by this author on: Oxford Academic Google Scholar R F Shonk, R F Shonk Divisions of Pharmacology and Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA Search for other works by this author on: Oxford Academic Google Scholar D D Miller D D Miller Divisions of Pharmacology and Medicinal Chemistry, College of Pharmacy, The Ohio State University, Columbus, Ohio 43210, USA Search for other works by this author on: Oxford Academic Google Scholar Journal of Pharmacy and Pharmacology, Volume 22, Issue 11, November 1970, Pages 869–870, https://doi.org/10.1111/j.2042-7158.1970.tb08461.x Published: 12 April 2011 Article history Received: 31 July 1970 Published: 12 April 2011
Molecular mechanisms involved in the control of glycogenosis in skeletal muscle by calcium ions and cyclic AMP (1987)

Conference Article| October 01 1987 Molecular mechanisms involved in the control of glycogenosis in skeletal muscle by calcium ions and cyclic AMP PHILIP COHEN PHILIP COHEN 1Department of Biochemistry, Unviersity of Dundee, Dundee DD14HN, U.K. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1987) 15 (5): 999–1001. https://doi.org/10.1042/bst0150999 Article history Received: April 10 1987 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation PHILIP COHEN; Molecular mechanisms involved in the control of glycogenosis in skeletal muscle by calcium ions and cyclic AMP. Biochem Soc Trans 1 October 1987; 15 (5): 999–1001. doi: https://doi.org/10.1042/bst0150999 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1987 Biochemical Society1987 Article PDF first page preview Close Modal You do not currently have access to this content.
P253 NEW SEROLOGICAL MARKERS FOR INFLAMMATORY BOWEL DISEASE ARE ASSOCIATED WITH EARLIER AGE AT ONSET, COMPLICATED DISEASE BEHAVIOR, RISK FOR SURGERY, AND NOD2/CARD15 GENOTYPE IN A HUNGARIAN IBD COHORT (2008)

Results: A significant differential expression of genes is found comparing Treg from HC to aCD (69 genes, 39 up-, 30 down-regulated) and HC to iCD (52 genes, 25 up-, 27 down-regulated). In both groups, 10 genes were upregulated more than 5fold. Transcripts for CCR4 were among the strongest expressed and showed an up-regulation of 5,0fold (HC vs aCD) and 6,4fold (HC vs iCD), respectively. FACS analysis showed that Treg express the highest level of CCR4 in peripheral T cells. In addition, migration studies showed that Treg migrate preferentially towards TARC -the ligand for CCR4. No significant difference in the percentage of CCR4+ Treg comparing HC to CD (57.911.3 vs. 54.412.7) could be detected, but comparison of normalized mean fluorescence intensity (MFI CCR4+/MFI CCR4-) showed a significant decrease in CD (15.83.7 vs 10.43.4; p=0.019). Immunohistochemistry showed a significant reduction of CCR4-expressing Treg in CD compared to DIV (44.4% 3.9 vs 29.0%8.0%; p=0.019). Conclusions: CCR4 is a possible target gene for Treg pathobiology in CD. Since TARC is abundantly expressed in diseased mucosa, the decreased expression of CCR4 points to an impaired mucosal Treg migration. Therefore, the migration capacity of Treg in CD is currently under investigation.
Intraplane to interplane optical interconnects with a high diffraction efficiency electro-optic grating (1997)

We report on a new optical interconnect architecture for three-dimensional, multiple electro-optic gratings with LiNbO(3) used in conjunction with substrate guided waves. First the operating mechanism of the system is studied in detail, and the momentum mismatch in the operating process of the system is also demonstrated. We then derive a new method for calculating coupling efficiency by introducing a compensation for the mismatch. This theoretical research allows the new optical interconnect architecture to provide a higher design accuracy and an optimized coupling efficiency, even though it is under the case of momentum mismatch. We achieve this result by introducing a substrate guided wave with 45 degrees bouncing angle and 100-V applied voltage. The successful design and its theoretical analysis will be helpful for research on the grating coupler.
Separation of leucine and isoleucine by electrospray ionization-high field asymmetric waveform ion mobility spectrometry-mass spectrometry (1999)

An electrospray ionization (ESI) source was used to generate gas-phase molecular anions of the amino acids leucine and isoleucine ((M-H)−; m/z −130), which were separated by high-field asymmetric waveform ion mobility spectrometry (FAIMS) and detected by quadrupole mass spectrometry (MS). This combination of ESI-FAIMS-MS enabled selective determination of either amino acid in mixtures that contained at least a 625-fold excess of the other. Comparisons with conventional ESI-MS showed a 50-fold improvement in the signal to background ratio for a 1 µM solution of leucine.
Incorporating Hip Arthroscopy Into A Practice. (2018)

Hip arthroscopy is one of the most rapidly growing areas in orthopaedic surgery because of increased awareness of nonarthritic hip pathologies, advanced imaging modalities, and advanced techniques to reproducibly manage nonarthritic hip pathologies within a deep soft-tissue envelope and a constrained joint. In addition, more academic medical centers are providing residents with education on hip arthroscopy, and many hip preservation fellowships and courses are helping increase awareness of nonarthritic hip pathologies. Nonarthritic hip pathologies currently managed via hip arthroscopy include nonrepairable labral lesions, femoroacetabular impingement, hip instability, and hip fractures. Periarticular hip pathologies currently managed via endoscopy include greater trochanteric pain syndrome, tendinopathy and tears of the gluteus medius and minimus, partial and complete hamstring avulsions, and sciatic nerve entrapment. Ischiofemoral impingement may be addressed endoscopically via the deep gluteal space. Orthopaedic surgeons should understand the role and safety of hip arthroscopy in the pediatric population, specifically in the management of slipped capital femoral epiphysis, Legg-Calvé-Perthes disease, and septic arthritis of the hip. The efficacy of hip arthroscopy is limited, and hip arthroscopy is relatively contraindicated in patients with osteoarthritis and hip dysplasia. Complications can occur and likely are underreported in patients who undergo hip arthroscopy. Orthopaedic surgeons should understand practical issues associated with incorporating hip arthroscopy into a practice, including the difficult learning curve associated with hip arthroscopy and the reluctance of some payors to reimburse procedures performed arthroscopically because hip arthroscopy is a relatively new technology.
IR Uses Of Diamond And Diamond-Like Thin Films (1989)

Pure diamond has excellent mechanical and infra red properties and would make an ideal window material were it readily available. Synthetic diamond films can be grown with good infra red transmission and used as protective coatings. Many coating requirements can already be met using diamond-like carbon films.
Safety and efficacy of complementary and alternative medicine in the treatment of autism spectrum disorder (2020)

OSF Registries, DOI: 10.17605/OSF.IO/ HA97R (https://osf.io/ha97r).
Expression of a full-length cDNA f (2016)

Intrinsic and acquired multidrug resistance (MDR) is an important problem in cancer therapy. MDR in human KB carcinoma cells selected for resistance to colchicine, vinblastine, or doxorubicin (former generic name adriamycin) is associated with overexpression of the gene, which encodes P-glycoprotein. We previously have isolated an over- lapping set of cDNA clones for the human MDRI gene from multidrug-resistant KB cells. Here we report the construction of a full4length cDNA for the human MDR1 gene and show that this reconstructed cDNA, when inserted into a retroviral expression vector containing' the long terminal repeats of Moloney leukemia virus or Harvey sarcoma virus, functions in mouse NIH 3T3 and human KB cells to confer the complete multidrug-resistance phenotype. These results suggest that the human MDR1 gene may be used as a positive selectable marker to introduce genes into human cells and to transform human cells to multidrug resistance without introducing nonhuman antigens.
A compact Doherty power amplifier for massive multi‐input multi‐output applications (2018)

Abstract A Doherty power amplifier composed of GaAs IPDs (Lange coupler and Doherty combiner) and GaN MMICs (carrier amplifier and peaking amplifier) is presented for 5G massive multi‐input multi‐output (MIMO). No input phase compensation circuit and no output offset lines were used for a compact design and the assembled Doherty power amplifier is as small as 6.6 mm × 3.6 mm with a saturation output power of 46 dBm. The asymmetric Doherty power amplifier exhibits a gain greater than 27.8 dB, PAE greater than 39.8% at average output power of 38 dBm, and ACLR less than −27.7 dBc using a 20 MHz LTE signal with 7.5 dB PAR across 3.6‐3.8 GHz.
Atomic layer etching of AlGaN using Cl2 and Ar gas chemistry and UV damage evaluation (2019)

The atomic layer etching (ALE) characteristics of AlGaN using Cl2 plasma in the modification step and Ar plasma in the removal step were investigated in comparison with conventional reactive ion etching (RIE). Although surface roughening and GaN composition changes were observed in the RIE process, the ALE process did not result in such changes. However, the etching damage of the AlGaN layer evaluated using cathodoluminescence in AlGaN/GaN stacked films in the case of ALE was 30% higher than that in RIE. This was attributed to the longer process time of ALE compared to RIE. The GaN layer underneath the AlGaN layer was also damaged. This could be mainly caused by UV photons during the modification step using Cl2 plasma. The authors introduced a modification step using Cl2 gas instead of Cl2 plasma; thus, the etching damage was successfully reduced while maintaining good surface characteristics.
Tailored Transverse Modes in High-Finesse Femtosecond Enhancement Cavities (2011)

Degenerate transverse modes are used to excite a field distribution with maximum on-axis intensity near the focus and avoiding a large on-axis aperture far away from the focus in a femtosecond resonator with finesse 3000.
Gate-last vs. gate-first technology for aggressively scaled EOT logic/RF CMOS (2011)

We report on gate-last technology for improved effective work function tuning with ∼200meV higher p-EWF at 7A EOT, ∼2x higher f max performance, and further options for channel stress enhancement than with gate-first by taking advantage of the intrinsic stress of metals and gate height dependence. Additional key features: 1) scavenging technique yielding UT-EOT down to ∼5A is demonstrated in gate-last, with high-k deposited first, through the use of an Etch-Stop-Layer with composite nature and similar TDDB reliability to gate-first; 2) controlled alloying for EWF engineering is obtained by careful material selection and tuned metals thicknesses ratio; 3) suppression of abnormal L gate - and W gate -dependence on J G , EOT and NBTI for devices with both high-k and metal deposited last (L gate ≥35nm, W gate ≥80nm) demonstrates the potential for improved UT-EOT control down to small devices with this scheme.