gebhart/patrepeval huggingface dataset:
Acoustic thermometry in the Northeast Pacific: 1983–1989 (1994)

Between 1983 and 1989, acoustic thermometers were used to measure basin-wide temperatures in the Northeast Pacific. One set of experiments was conducted between the Kaneohe source (133 Hz, 60-ms resolution) and about ten U. S. Navy SOSUS stations. The other set of experiments was conducted between three moored sources (250 Hz, 16-ms resolution) and the same SOSUS stations. Over 14 of the 16 sections, the multipaths can be understood using ray theory. Even though sound from the Kaneohe source interacts with the bottom many times, ray theory succeeds in interpreting the multipath pattern. In the summer of 1987, the Northeast Pacific is colder than climatology based on Levitus’ atlas. [Work supported by Advanced Research Projects Agency and Office of Naval Research.]
Treatment and Outcomes of Reverse Shoulder Arthroplasty Dislocations (2017)

Background Dislocation is a challenging complication after reverse shoulder arthroplasty (RSA). We sought to evaluate the outcome of nonoperative and operative management of the dislocation after primary and revision RSA. Methods Between 2006 and 2013, dislocation occurred in 12/1081 primary RSAs (1.1%) and 15/342 revision RSAs (4.4%). Seventeen (69%) shoulders dislocated within 3 months of surgery. Ten (68%) patients underwent revision RSA for prosthetic instability. Mean age was 69 years, and mean follow-up after index RSA was 4 years. Results Closed reduction and bracing achieved a stable shoulder in 60% (3/5 patients) after primary and 20% (1/5 patients) after revision RSA dislocation. Operative management achieved a stable shoulder in 88% (7/8 patients) of primary and 64% (7/11 patients) of revision RSAs ( P = .40). Overall, 9 shoulders (33%) had persistent instability at the final follow-up: 2/12 (17%) primaries versus 7/15 (47%) revisions ( P = .08). Preoperative prosthetic instability was the main risk factor for chronic instability in the revision cohort ( P = .02). Worse functional outcomes were associated with the dislocation of a revision RSA ( P = .02). Conclusion After primary RSA dislocations, closed reduction is successful in half, while revision surgery is successful in 85% of cases. Conversely, closed reduction of a dislocated revision RSA is rarely successful, while revision surgery is successful 65% of the time. Every attempt should be made to achieve stability at the time of primary and revision RSA, since reduction or revision surgery does not guarantee the restoring stability.
An unshunted comparator as a device for quantum measurements (2003)

The unshunted single-flux-quantum SFQ comparator is described for the first time. Its dynamic behavior is surprisingly similar to the familiar resistively-shunted SFQ comparator. For certain parameter ranges both junctions of the comparator may pulse at the same time to create a reflected anti-pulse. This phenomenon is utilized in a new SFQ comparator design with better coherence properties for qubit readout. Considerations of quantum noise for the unshunted SFQ comparator are discussed.
Einfluss der RSV-Prophylaxe mit Palivizumab bei VLBW-Frühgeborenen auf die Lungenfunktion im Alter von 5 Jahren (2023)

Einleitung Extreme Unreife, die Bronchopulmonale Dysplasie und pulmonale Infektionen mit dem Respiratory-Syncytial-Virus (RSV) gehören zu den Hauptrisikofaktoren für eine langfristige Beeinträchtigung der Lungenfunktion bei Frühgeborenen mit einem Geburtsgewicht < 1500g (VLBWI, very-low-birth-weight infants). Aktuelle Leitlinien empfehlen die saisonale Impfung mit Palivizumab bei Frühgeborenen mit hohem Risiko für chronische Lungenerkrankungen. Da Daten aus klinischen Studien fehlen, ist bislang jedoch unklar, ob die Palivizumab-Impfung von Hochrisikokindern zu einer Verbesserung der langfristigen Lungenfunktion führt.
Murine Whole-Organ Immune Cell Populations Revealed by Multi-epitope-Ligand Cartography (2012)

Multi-epitope-ligand cartography (MELC) is an innovative high-throughput fluorescence microscopy-based method. A tissue section is analyzed through a repeated cycling of (1) incubation with a fluorophore-labeled antibody, (2) fluorescence imaging, and (3) soft bleaching. This method allows staining of the same tissue section with up to 100 fluorescent markers and to analyze their toponomic expression using further image processing and pixel-precise overlay of the corresponding images. In this study, we adapted this method to identify a large panel of murine leukocyte subpopulations in a whole frozen section of a peripheral lymph node. Using the resulting antibody library, we examined non-inflamed versus inflamed tissues of brain and spinal cord in the experimental autoimmune encephalomyelitis (EAE) model. The presence and activity of specific leukocyte subpopulations (different T cell subpopulations, dendritic cells, macrophages, etc.) could be assessed and the cellular localizations and the corresponding activation status in situ were investigated. The results were then correlated with quantitative RT-PCR.
Insight into the Willgerodt-Kindler Reaction of ω-Haloacetophenone Derivatives: Mechanistic Implication (2014)

This paper reports efforts aimed at tuning up the synthesis of a compound library centered on the general template 2-amino-1-phenyl-2-thioxoethanone taking the condensation of ω -haloacetophenone, octasulfur, and morpholine as pilot reaction. Considerations about atomic economy were found extremely precious in selecting the best starting halo-reagent. A one-pot practical method based on use of 2-bromo-1-phenylethanone as substrate and N,N -dimethylformamide as solvent can be easily scaled up to gram amounts (72% yield). Based on this synthetic approach, some more specific examples are reported.
Observation of Surface Acoustic Wave Propagation on a Quartz Ball with Concave Proximate Electrodes (2008)

We evaluated the characteristics of roundtrip propagation on a ball surface acoustic wave (SAW) device by controlling the approach of electrodes to the quartz ball. In order to investigate the relationship between the interdigital transducer (IDT) position and the exponential attenuation in the roundtrips of SAW, we brought a concave glass plate with an IDT towards the equatorial belt (Z-axis cylinder) of the quartz ball, and transmitted and received a SAW. In this study, the precision of the apparatus was improved, and as a result, it was found that roundtrip of SAW attenuates exponentially when the IDT is at a certain position. The specific positions were not always at the Z-axis cylinder but distributed around it with the meander belt with a period of 120°. By fabricating an IDT at such positions, it is expected that the performance and reproducibility of ball SAW sensors will be enhanced.
Epoxyquinomicins A, B, C and D, New Antibiotics from Amycolatopsis. I. Taxonomy, Fermentation, Isolation and Antimicrobial Activities. (1997)

A new structural class of the antibiotic, epoxyquinomicins A, B, C and D were isolated from the culture broth of the strain MK299-95F4, which was related to Amycolatopsis sulphurea. Antimicrobial activity of epoxyquinomicins A and B were weak against Gram-positive bacteria, and epoxyquinomicins C and D showed almost no antimicrobial activity and no cytotoxicity. All these antibiotics showed improvement of collagen induced arthritis in vivo.
Image-based 3D acquisition of archaeological heritage and applications (2001)

In this paper an approach is presented that obtains virtual models from sequences of images. The system can deal with uncalibrated image sequences acquired with a hand-held camera. Based on tracked or matched features the relations between multiple views are computed. From this both the structure of the scene and the motion of the camera are retrieved. The ambiguity on the reconstruction is restricted from projective to metric through auto-calibration. A flexible multi-view stereo matching scheme is used to obtain a dense estimation of the surface geometry. From the computed data virtual models can be constructed or, inversely, virtual models can be included in the original images.
Maximally selective single cell target for circuit control in epilepsy (2020)

Abstract Neurological and psychiatric disorders are associated with pathological neural dynamics. The fundamental connectivity patterns of cell-cell communication networks that enable pathological dynamics to emerge remain unknown. We studied epileptic circuits using a newly developed integrated computational pipeline applied to cellular resolution functional imaging data. Control and preseizure neural dynamics in larval zebrafish and in chronically epileptic mice were captured using large-scale cellular-resolution calcium imaging. Biologically constrained effective connectivity modeling extracted the underlying cell-cell communication network. Novel analysis of the higher-order network structure revealed the existence of ‘superhub’ cells that are unusually richly connected to the rest of the network through feedforward motifs. Instability in epileptic networks was causally linked to superhubs whose involvement in feedforward motifs critically enhanced downstream excitation. Disconnecting individual superhubs was significantly more effective in stabilizing epileptic networks compared to disconnecting hub cells defined traditionally by connection count. Collectively, these results predict a new, maximally selective and minimally invasive cellular target for seizure control. Highlights Higher-order connectivity patterns of large-scale neuronal communication networks were studied in zebrafish and mice Control and epileptic networks were modeled from in vivo cellular resolution calcium imaging data Rare ‘superhub’ cells unusually richly connected to the rest of the network through higher-order feedforward motifs were identified Disconnecting single superhub neurons more effectively stabilized epileptic networks than targeting conventional hub cells defined by high connection count. These data predict a maximally selective novel single cell target for minimally invasive seizure control
<title>Masks for laser ablation technology: new requirements and challenges</title> (1995)

Laser ablation is used as a dry patterning process in which an intense beam of light from an excimer laser is used to directly pattern a material. The laser ablation patterning process is relatively new and has many advantages such as low cost and high throughput. This process has found extensive applications in the microelectronics industry for patterning of polymer materials. A typical laser ablation tool is very similar to a conventional optical wafer stepper, consisting of an illumination source, optics, mask and a substrate. The primary difference is the wavelength and the intensity of the light used in the ablation process. Conventional chromium coated quartz masks are incompatible with laser ablation due to a low damage threshold. This paper discusses a mask technology which has been developed specifically for excimer laser ablation. The mask fabrication processes and results are discussed.
RhoGAP mediates ceramide activation of phosphatidylglycerolphosphate synthase and drug response in Chinese hamster ovary cells (2008)

Promoter trap mutagenesis was used to isolate an etoposide resistant CHO cell line. This resistant CHO‐K1 line, named E91, showed cross resistance to C2‐ceramide (N‐acetylsphingosine) mediated cell killing. The promoter trap retrovirus integrated into intron one‐two of the Dlc‐2 ( Stard13 ) RhoGap gene. E91 cells showed elevated GTP bound RhoA levels compared with the parental line suggesting that retrovirus integration had inactivated one of the Dlc‐2 RhoGap alleles. To test if E91 cells were impaired in an intracellular ceramide‐regulated process not directly related to cell killing, we measured mitochondrial phosphatidylglycerolphosphate (PGP) synthase and phospholipase A 2 enzyme activities in cells after C2‐ceramide addition. Parental cells showed elevated enzyme activities after treatment with C2‐ceramide or TNFα but, not the E91 cells. These results indicate that intracellular ceramide signaling was defective in E91 cells due to increased levels of active GTP bound RhoA. RNA knockdown experiments of the Dlc2 RhoGap resulted in increased GTP bound RhoA and reduced induction of PGP synthase after C2‐ceramide addition compared with controls. Expression of a dominant negative RhoA in the E91 cell line allowed induction of PGP synthase by ceramide. This study is the first report for the regulation of a phospholipid biosynthetic enzyme through a G protein. (Supported by the CIHR, NCIC, G.M.H. is a Canada Research Chair in Molecular Cardiolipin Metabolism).
GROUPNESS RACIAL E FLUTUAÇÕES ATITUDINAIS DE PARDOS ENTRE FRONTEIRAS SIMBÓLICAS E SOCIAIS (2019)

Neste artigo, examinamos a permeabilidade das fronteiras simbólicas raciais a partir da identificação e análise de atitudes referentes: (1) ao preconceito; (2) à mistura racial e (3) ao apoio às políticas de cotas. Mais especificamente, exploramos a hipótese de que as opiniões posicionais dos pardos, em virtude da sua localização intermediária no espectro de cor brasileiro, são marcadas por uma flutuação entre os padrões adotados por brancos e por pretos. Verificamos que há convergência atitudinal entre os grupos raciais, com exceção da discriminação racial, temática na qual brancos e pardos assumem padrões similares. Este resultado fortalece a visão dos indivíduos pardos como negociadores de fronteiras – seja ao se distanciar dos pretos, como no racismo, ou se aproximar deles, como no caso das cotas – em consonância com as identidades e interesses implicados em sua posição no continuum de cor.
The Energy Return on Investment for Algal Biocrude: Results for a Research Production Facility (2010)

This study is an experimental determination of the energy return on investment (EROI) for algal biocrude production at a research facility at the University of Texas at Austin (UT). During the period of this assessment, algae were grown at several cultivation scales and processed using centrifugation for harvesting, electromechanical cell lysing, and lipid separation in an enhanced coalescence membrane. The separated algal lipids represent a biocrude product that could be refined into fuel. To determine the EROI, a second order analysis was conducted, which includes direct and indirect energy flows, but does not consider capital energy expenses. At the time that the data in this study was collected, the research program was focused on improving biomass and lipid productivity. As a result, some higher efficiency processing steps were replaced by lower efficiency ones to permit other experiments. Although the production process evaluated here was energy negative, the majority of the energy consumption resulted from non-optimized growth conditions. Therefore, the experimental results do not represent an expected typical case EROI for algal fuels, but rather outline the important parameters to consider in such an analysis. The results are the first known experimental energy balance for an integrated algal biocrude production facility. A Reduced Case is presented that speculates the energy use for a similar system in commercial-scale production. In addition, an analytical model that is populated with data that have been reported in the literature is presented. For the experiments, the Reduced Case, and Literature Model, the estimated EROI was 1.3 × 10−3, 0.13, and 0.57, respectively (refining energy requirements are not included in the experimental or Reduced Case EROI value). These results were dominated by growth inputs (96.59%, 94.15%, and 76.32% of the total energy requirement, respectively). For the experiments and Literature Model, lipid separation was the most energy intensive processing step (2.47% and 10.06%, respectively), followed by harvesting, refining, and then electromechanical cell lysing.
Electric field stimulation through a biodegradable polypyrrole‐co‐polycaprolactone substrate enhances neural cell growth (2013)

Nerve guidance conduits (NGCs) are FDA-approved devices used to bridge gaps across severed nerve cables and help direct axons sprouting from the proximal end toward the distal stump. In this article, we present the development of a novel electrically conductive, biodegradable NGC made from a polypyrrole-block-polycaprolactone (PPy-PCL) copolymer material laminated with poly(lactic-co-glycolic acid) (PLGA). The PPy-PCL has a bulk conductivity ranging 10-20 S/cm and loses 40 wt % after 7 months under physiologic conditions. Dorsal root ganglia (DRG) grown on flat PPy-PCL/PLGA material exposed to direct current electric fields (EF) of 100 mV/cm for 2 h increased axon growth by 13% (± 2%) toward either electrode of a 2-electrode setup, compared with control grown on identical substrates without EF exposure. Alternating current increased axon growth by 21% (±3%) without an observable directional preference, compared with the same control group. The results from this study demonstrate PLGA-coated PPy-PCL is a unique biodegradable material that can deliver substrate EF stimulation to improve axon growth for peripheral nerve repair.
High-throughput proteomics of nanogram-scale samples with Zeno SWATH DIA (2022)

Abstract The ability to conduct high-quality proteomic experiments in high throughput has opened new avenues in clinical research, drug discovery, and systems biology. Next to an increase in quantitative precision, recent developments in high-throughput proteomics have also gained proteomic depth, to the extent that earlier gaps between classic and high-throughput experiments have significantly narrowed. Here we introduce and benchmark Zeno SWATH, a data-independent acquisition technique that employs a linear ion trap pulsing (Zeno trap pulsing) in order to increase proteomic depth and dynamic range in proteomic experiments. Combined with the high acquisition speed, these gains in sensitivity are particularly attractive for conducting high-throughput proteomics experiments with high chromatographic flow rates and fast gradients. We demonstrate that when combined with either micro-flow- or analytical-flow-rate chromatography, Zeno SWATH increases protein identification in complex samples 5- to 10-fold when compared to current SWATH acquisition methods on the same instrument. Using 20-min micro-flow chromatography, Zeno SWATH identified &gt; 6,000 proteins from a 62.5 ng load of human cell lysate with more than 5,000 proteins consistently quantified in triplicate injections with a median CV of 6%. Using 5-min analytical-flow-rate chromatography (800 µl/min), Zeno SWATH identified 4,907 proteins from a triplicate injection of 2 µg of a human cell lysate; or more than 3,000 proteins from 250 ng tryptic digest. Zeno SWATH hence facilitates precise proteomic experiments with small sample amounts using a fast and robust high flow-rate chromatographic method, broadening the application space that requires precise proteomic experiments on a large scale.
A New Approach to Modeling the Flow Curve of Hot Deformed Austenite (2011)

A new, more physically realistic and practically useful model is presented for the simulation of high temperature austenite flow curves. It is an extension of our earlier empirical model based on the Avrami kinetics of dynamic recrystallization. In the new approach, the normalization parameter is expressed in terms of the fractional recrystallization and not the amount of softening. Compression experiments carried out on a Nb-modified plain carbon steel enable the simulated flow curves and progress of recrystallization predicted by the two models to be compared.
Patterns of Electrostatic Charge and Discharge in Contact Electrification (2008)

Wiederkehrender Zusammenbruch: Die Dynamik der Kontaktelektrifizierung einer über eine isolierende Platine rollenden Metallkugel wurde untersucht. Die Daten verweisen auf einen Ionentransfer als Aufladungsprozess (siehe Schema), der durch wiederkehrende Entladungen aufgrund von dielektrischem Luftdurchschlag unterbrochen wird.
34.4Mbps 1.56Tbps/W DEFLATE Decompression Accelerator Featuring Block-Adaptive Huffman Decoder in 14nm Tri-Gate CMOS for IoT Platforms (2018)

A 9,296μm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> DEFLATE accelerator targeted for firmware decompression in battery-constrained IoT platforms is fabricated in 14nm tri-gate CMOS, and operates over a wide supply range of 210-900m V. Dual-ALU block-adaptive Huffman decoder enables simultaneous evaluation of a pair of code-lengths with opportunistic skipping of non-existent symbols improving throughput by 34% to 1.65Gb/s at 750mV, 25°C, while in-line literal packing and fenced-record generation achieves 63% memory bandwidth reduction for LZ77 reconstruction. Absence of register file and CAM circuits result in a fully-synthesizable implementation enabling ultra-low voltage operation with peak energy-efficiency of 1.56Tbps/W and 34.4Mbps throughput at 22μW total power consumption measured at 310mV.
Versal Network-on-Chip (NoC) (2019)

Xilinx Versal Adaptable Compute Acceleration Platform (ACAP) is a new software-programmable heterogenous compute platform. The slowing of Moores law and the everpresent need for higher levels of compute performance has spurred the development of many domain specific accelerator architectures. ACAP devices are well suited to take advantage of this trend. They provide a combination of hardened heterogenous compute and IO elements and programmable logic. Programmable logic allows the accelerator to be customized in order to accelerate the whole application. The Versal Networkon-Chip (NoC) is a programmable resource that interconnects all of these elements. This paper outlines the motivation for a hardened NoC within a programmable accelerator platform and described the Versal NoC.
An Asynchronous Power Aware and Adaptive NoC Based Circuit (2009)

In complex embedded applications, optimisation and adaptation of both dynamic and leakage power have become an issue at SoC grain. A fully power-aware globally-asynchronous locally-synchronous network-on-chip (NoC) circuit is presented in this paper. Network-on-chip architecture combined with a globally-asynchronous locally-synchronous paradigm is a natural enabler for DVFS mechanisms. The circuit is arranged around an asynchronous network-on-chip providing scalable communication and a 17 Gb/s throughput while automatically reducing its power consumption by activity detection. Both dynamic and static power consumptions are globally reduced using adaptive design techniques applied locally for each synchronous NoC units. No fine control software is required during voltage and frequency scaling. Power control is localized and a minimal latency cost is observed.
Oxygen as a control factor in embryogenesis of legume seeds. (2003)

A summary of findings on O2 distribution within seeds (of Vicia faba and Pisum sativum) in relation to seed development and the environment (the development of legume embryos in hypoxic environments, avoidance of anoxia by embryo tissues, and impact of low oxygen on seed metabolism) is presented. A possible control function of O2 deficiency in legume seed development is suggested based on the analysis of data on energy status, metabolite levels and respiratory activity.
Broadband negative refraction of hyperbolic highly squeezed graphene plasmons (2018)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text J. Jiang, X. Lin, Y. Yang, I. Kaminer, M. Soljačić, and B. Zhang, "Broadband negative refraction of hyperbolic highly squeezed graphene plasmons," in Conference on Lasers and Electro-Optics, OSA Terchnical Digest (online) (Optica Publishing Group, 2018), paper FF2L.6. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article