gebhart/patrepeval huggingface dataset:
RF properties of high-T/sub c/ superconductors (1989)

An investigation was conducted of the RF properties of high-T/sub c/ superconductors over a wide range of temperatures, frequencies and RF field amplitudes. Both bulk polycrystalline samples and thick films on silver substrates were tested. At 150 MHz and 4.2 K, surface resistances of 18 mu Omega at low RF field and 3.6 m Omega at an RF field of 270 G were measured. All samples showed a strong dependence of the surface resistance on RF field. However, no breakdown of the superconducting state was observed up to the highest field achieved (320 G).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Shape memory and breathable waterproof properties of polyurethane nanowebs (2012)

An intelligent textile with optimal environmental responses was developed from electrospun nanowebs with controllable pore structures via the spinning conditions. The use of shape memory polyurethane allowed the material’s shape to be retained and recovered through heating. The thickness of the electrospun nanoweb was varied so as to manufacture the membrane with various pore diameters. The samples were evaluated for shape memory performance, air and water vapor permeability. All samples showed shape recoveries of at least 99% and shape retentions of at least 94%. Increasing the thickness, increased the shape retention but slightly reduced the shape recovery. Pore size decreased with increasing thickness, thus decreasing air and water vapor permeability. Stretched nanowebs showed the greatest differences in water vapor permeability at 10°C with 90% RH and at 15°C with 90% RH compared with original nanowebs.
Fiber Optical Methane Sensors Using Functional Metal Oxide Nanomaterials (2016)

This paper reports fiber optic sensors for methane measurements based on evanescent optical interactions. Porous Pd-SnO2 thin film synthesized by block copolymer template scheme was coated on D-shaped fiber as functional sensing materials.
Ultrastructural immunocytochemical localization of calmodulin in cultured cells. (1983)

Using an antibody prepared against performic acid-treated calmodulin, we have localized calmodulin in cultured fibroblastic cells by immunofluorescence and immunoelectron microscopy. In interphase cells, calmodulin was found to be diffusely distributed throughout the cytosol. An increased amount of calmodulin was found in the pericentriolar region of interphase cells. No significant aggregation of calmodulin was found in association with microfilaments, peripheral cytoplasmic microtubules or clathrin-coated structures. Calmodulin was present in moderate amounts in microvilli, ruffles, and zeiotic blebs of the cell surface. In motitic cells, calmodulin was found concentrated in the pericentriolar region, and appeared to concentrate along radiating spindle microtubules proximal to the centrioles. Redistribution of calmodulin was seen between early and late telophase, in which the pericentriolar pattern of calmodulin in early telophase shifted to an aggregation on the intercellular bridge, with a large part of the midbody portion of the bridge being devoid of calmodulin. These results show that calmodulin is distributed throughout the cytosol, but is markedly concentrated in the region of the microtubule organizing center in interphase cells, as well as in elements of the mitotic spindle apparatus. This distribution suggests that calmodulin has a regulatory role in the organization and function of microtubules during interphase, as well as during mitosis.
Gravure de matériaux à faible constante diélectrique (2002)

National audience
Photoregulation of Cellular Morphology during Complementary Chromatic Adaptation Requires Sensor-Kinase-Class Protein RcaE in Fremyella diplosiphon (2008)

We used wild-type UTEX481; SF33, a shortened-filament mutant strain that shows normal complementary chromatic adaptation pigmentation responses; and FdBk14, an RcaE-deficient strain that lacks light-dependent pigmentation responses, to investigate the molecular basis of the photoregulation of cellular morphology in the cyanobacterium Fremyella diplosiphon. Detailed microscopic and biochemical analyses indicate that RcaE is required for the photoregulation of cell and filament morphologies of F. diplosiphon in response to red and green light.
34 GB multilevel-enabled rewritable system using blue laser and high-NA optics (2003)

This paper evaluates MultiLevel (ML) margin-testing results as applied to a blue-laser recording-base with 0.85 NA lens and media with 0.1 mm cover for an 8-level trellis-coded modulation system that encodes 2.5 user-bits per data-cell. The ML system tested was originally developed on a CD-R/RW base to achieve 2 GB. Margin testing results compare favorably to binary system performance on this same tester and produced a 36% increase in capacity above a 25 GB base.
The Western Arctic Linkage Experiment (WALE): Overview and Synthesis (2008)

Abstract The primary goal of the Western Arctic Linkage Experiment (WALE) was to better understand uncertainties of simulated hydrologic and ecosystem dynamics of the western Arctic in the context of 1) uncertainties in the data available to drive the models and 2) different approaches to simulating regional hydrology and ecosystem dynamics. Analyses of datasets on climate available for driving hydrologic and ecosystem models within the western Arctic during the late twentieth century indicate that there are substantial differences among the mean states of datasets for temperature, precipitation, vapor pressure, and radiation variables. Among the studies that examined temporal trends among the alternative climate datasets, there is not much consensus on trends among the datasets. In contrast, monthly and interannual variations of some variables showed some correlation across the datasets. The application of hydrology models driven by alternative climate drivers revealed that the simulation of regional hydrology was sensitive to precipitation and water vapor differences among the driving datasets and that accurate simulation of regional water balance is limited by biases in the forcing data. Satellite-based analyses for the region indicate that vegetation productivity of the region increased during the last two decades of the twentieth century because of earlier spring thaw, and the temporal variability of vegetation productivity simulated by different models from 1980 to 2000 was generally consistent with estimates based on the satellite record for applications driven with alternative climate datasets. However, the magnitude of the fluxes differed by as much as a factor of 2.5 among applications driven with different climate data, and spatial patterns of temporal trends in carbon dynamics were quite different among simulations. Finally, the study identified that the simulation of fire by ecosystem models is particularly sensitive to alternative climate datasets, with little or no fire simulated for some datasets. The results of WALE identify the importance of conducting retrospective analyses prior to coupling hydrology and ecosystem models with climate system models. For applications of hydrology and ecosystem models driven by projections of future climate, the authors recommend a coupling strategy in which future changes from climate model simulations are superimposed on the present mean climate of the most reliable datasets of historical climate.
Disorder-induced phase coexistence in bulk doped manganites and its suppression in nanometer-sized crystals: The case ofLa0.9Ca0.1MnO3 (2007)

$X$-band electron magnetic resonance together with dc and ac magnetic measurements were employed for comparative study of magnetic ordering in bulk and nanometer-sized ${\mathrm{La}}_{0.9}{\mathrm{Ca}}_{0.1}\mathrm{Mn}{\mathrm{O}}_{3}$ single crystals. A dramatic difference between bulk crystal showing mixed magnetic state, constituted by coexisting canted antiferromagnetic $A$-type matrix and nanometer sized ferromagnetic clusters, and the nanocrystalline form of the same compound, showing mainly ferromagnetic ordering, has been revealed. The complementary study of the structural state and analysis of the electron paramagnetic resonance data in terms of the proposed theoretical model have enlightened the reasons for the observed difference in the magnetic order. The results suggest that the change in magnetic order has an intrinsic nature and is not induced by nonstoichiometry. The cation composition and the oxygen stoichiometry of bulk and nanosized crystals were determined to be the same within the experimental accuracy. Nanometer-sized crystals of ${\mathrm{La}}_{0.9}{\mathrm{Ca}}_{0.1}\mathrm{Mn}{\mathrm{O}}_{3}$ are characterized by better chemical and crystalline homogeneity arising both from different fabrication techniques and reduced crystallites size. This effect induces a transition from an inhomogeneous confined state of charge carriers in chemically disordered bulk crystal to a more mobile one in an impuritylike band in homogeneous nanocrystals, resulting in the change of magnetic ordering. A realistic model describing size assisted change of magnetic order in doped manganites has been proposed to interpret the data. The experimental results and their analysis indicate that a chemical/magnetic disorder has a strong impact on the magnetic state and the phase diagram of doped manganites.
A computational approach to predicting cell growth on polymeric biomaterials (2005)

A predictive model that can correlate the chemical composition of a biomaterial with the biological response of cells that are in contact with that biomaterial would represent a major advance and would facilitate the rational design of new biomaterials. As a first step toward this goal, we report here on the use of Logical Analysis of Data (LAD) to model the effect of selected polymer properties on the growth of two different cell types, rat lung fibroblasts (RLF, a transformed cell line), and normal foreskin fibroblasts (NFF, nontransformed human cells), on 112 surfaces obtained from a combinatorially designed library of polymers. LAD is a knowledge extraction methodology, based on using combinatorics, optimization, and Boolean logic. LAD was trained on a subset of 62 polymers and was then used to predict cell growth on 50 previously untested polymers. Experimental validation indicated that LAD correctly predicted the high and low cell growth polymers and found optimal ranges for polymer chemical composition, surface chemistry, and bulk properties. Particularly noteworthy is that LAD correctly identified high-performing polymer surfaces, which surpassed commercial tissue culture polystyrene as growth substratum for normal foreskin fibroblasts. Our results establish the feasibility of using computational modeling of cell growth on flat polymeric surfaces to identify promising "lead" polymers for applications that require either high or low cell growth.
Intrinsic tryptophan fluorescence of bovine liver adenosine kinase, characterization of ligand binding sites and conformational changes (1994)

Bovine liver adenosine kinase is a 45-kDa monomeric protein which exhibits a characteristic intrinsic tryptophan fluorescence with a maximal excitation at 284 nm and an emission peak centered at 335 nm. A total of three tryptophan residues/molecule has been estimated by using a fluorescence titration method. Low values of Stern-Volmer quenching constants in the presence of either acrylamide or iodide (4.2 M-1 or 1.5 M-1, respectively) indicated that the tryptophan residues are relatively buried in the native molecule. Tryptophan residues also showed a high heterogeneity, with a fractional accessible fluorescence value for iodide of 0.65. The enzyme fluorescence was very sensitive to substrate binding, which induced a marked fluorescence quenching, a lower tryptophan accessibility to acrylamide and iodide, and an increase in the tryptophan heterogeneity. ADP or ATP showed a monophasic saturation curve consistent with the existence of one binding site. In contrast, adenosine and AMP gave biphasic saturation curves, suggesting the existence of at least two binding sites, with a high and a low affinity. The presence of MgCl2 increased the affinity of ATP or ADP, whereas the binding of adenosine or AMP was not affected.
On the Thermal Management of3D‐ICs: From Backside to Volumetric Heat Removal (2019)

This chapter presents various novel heat removal approaches to compile a roadmap toward true 3D integration. A topology change from single side to dual side and volumetric heat removal is a more disruptive option to reduce the thermal constraints on 3D chip stacks. Designing a thermal underfill is a multivariable problem with targets for mechanical, thermomechanical, and electrical properties, besides thermal aspects. Therefore, the complete set of properties needs to be studied in order to guide the experimental work regarding the choice of materials and geometries. Effective properties of percolating and neck-based thermal underfills can be computed using finite element methods. Bringing a liquid coolant closer to the heat source changes the package topology. The chapter overviews the consequences of such a topology change. Using liquid coolant within the package relaxes the thermal requirements on some package parts - such as rendering Cu lids obsolete - but adds requirements on loads, sealing, replaceability, and reliability.
Supplementary Table S2 from A Clinical PET Imaging Tracer ([<sup>18</sup>F]DASA-23) to Monitor Pyruvate Kinase M2–Induced Glycolytic Reprogramming in Glioblastoma (2023)

&lt;p&gt;[18F]DASA-23 administered activity in brain tumor patients&lt;/p&gt;
A high reliability and low loss 3-phase gate driver IC with a novel soft gate drive circuit for 42V motor generator system (2004)

We have developed a three-phase driver IC for the 42V motor generator automotive system using a 100V class SOI isolated 0.5/spl mu/m three metal layer bipolar CMOS LDMOS process SOIPIC (SOI Intellectual Property Power IC). This IC has a soft gate drive function with a new concept of loss minimization for a low on-state-resistance 100V 500A class trench power MOSFET.
Four-dimensional Microscope-Integrated Optical Coherence Tomography to Visualize Suture Depth in Strabismus Surgery (2017)

The authors report the use of swept-source microscope-integrated optical coherence tomography (SS-MIOCT), capable of live four-dimensional (three-dimensional across time) intraoperative imaging, to directly visualize suture depth during lateral rectus resection. Key surgical steps visualized in this report included needle depth during partial and full-thickness muscle passes along with scleral passes. [J Pediatr Ophthalmol Strabismus. 2017;54:e1-e5.].
Corynebacterium Prosthetic Joint Infection (2012)

Identification of Corynebacterium species may be challenging. Corynebacterium species are occasional causes of prosthetic joint infection (PJI), but few data are available on the subject. Based on the literature, C. amycolatum, C. aurimucosum, C. jeikeium, and C. striatum are the most common Corynebacterium species that cause PJI. We designed a rapid PCR assay to detect the most common human Corynebacterium species, with a specific focus on PJI. A polyphosphate kinase gene identified using whole-genome sequence was targeted. The assay differentiates the antibiotic-resistant species C. jeikeium and C. urealyticum from other species in a single assay. The assay was applied to a collection of human Corynebacterium isolates from multiple clinical sources, and clinically relevant species were detected. The assay was then tested on Corynebacterium isolates specifically associated with PJI; all were detected. We also describe the first case of C. simulans PJI.
Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms (2010)

Cardiomyocyte proliferation is high in early development and decreases progressively with gestation, resulting in the lack of a robust cardiomyocyte proliferative response in the adult heart after injury. Little is understood about how both cell-autonomous and nonautonomous signals are integrated to regulate the balance of cardiomyocyte proliferation during development. In this study, we show that a single transcription factor, Foxp1, can control the balance of cardiomyocyte proliferation during development by targeting different pathways in the endocardium and myocardium. Endocardial loss of Foxp1 results in decreased Fgf3/Fgf16/Fgf17/Fgf20 expression in the heart, leading to reduced cardiomyocyte proliferation. This loss of myocardial proliferation can be rescued by exogenous Fgf20, and is mediated, in part, by Foxp1 repression of Sox17. In contrast, myocardial-specific loss of Foxp1 results in increased cardiomyocyte proliferation and decreased differentiation, leading to increased myocardial mass and neonatal demise. We show that Nkx2.5 is a direct target of Foxp1 repression, and Nkx2.5 expression is increased in Foxp1-deficient myocardium. Moreover, transgenic overexpression of Nkx2.5 leads to increased cardiomyocyte proliferation and increased ventricular mass, similar to the myocardial-specific loss of Foxp1. These data show that Foxp1 coordinates the balance of cardiomyocyte proliferation and differentiation through cell lineage-specific regulation of Fgf ligand and Nkx2.5 expression.
Glycoconjugate Vaccines: The Clinical Journey (2018)

We review the clinical journey of glyconjugate vaccines from their inception in the 1980s to contemporary vaccines and their positive public health impact. We focus on novel and ground breaking clinical trials, particularly those leading to marketing approvals for new categories of vaccines. Glyconjugate vaccines based on capsular polysaccharides have been highly successful against Haemophilus influenzae type b, a growing number of Streptococcus pneumoniae serotypes and Neisseria meningitidis serogroups A, C, W and Y. Glycoconjugate vaccines may extend this success to other encapsulated bacteria such as Salmonella typhi, Group B Streptococcus and Staphylococcus aureus as well as Shigella and Escherichia coli.
Molecular Imaging with Reporter Genes (2010)

Reporter genes have been used for several decades to study regulation of gene expression in vivo. However, it was little more than a decade ago that a new class of reporter genes was developed for imaging molecular events within living subjects. By following the interactions of protein molecules, researchers can resolve the complex chemical pathways that living cells utilise. This book focuses on this group of imaging reporter genes, starting with detailed descriptions of all reporter genes from different imaging modalities, including optical, MRI, and radionuclide-based imaging. Key scientists in the field explain how to enhance reporter gene imaging utility through instrumentation and the various applications of this technology. This is the first comprehensive book on all aspects of reporter gene imaging, detailing what is known in the field and future goals for research. Investigators in biomedical sciences, physicians, and the biotechnology and pharmaceutical industries will benefit from topics covered.
Force Sensor-less Robust Tracking Servo System Suppressing Periodic Disturbance and Sudden Disturbance for Optical Disk System (2006)

This paper proposes a new force sensor-less robust tracking servo system, which detects and suppresses both the periodic disturbance and the sudden disturbance without force sensor. The proposed system estimates both the periodic disturbance and the sudden disturbance by using a new sudden disturbance observer and the memory of tracking error. In the proposed system, the influence of sudden disturbance is suppressed by the proposed sudden disturbance observer. On the other hand, the influence of periodic disturbance is suppressed by means of ZPET feed-forward servo system, respectively. The experimental results point out that the proposed tracking servo system has a precise tracking response against both the periodic disturbance and the sudden disturbance.
Computing &#x210B;<inf>&#x221E;</inf> norms of time-delay systems (2009)

In this paper we consider the computation of H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> norm of retarded time-delay systems with discrete pointwise state delays. It is well known that in the finite dimensional case H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> norm of a system is computed using the connection between the singular values of the transfer function and the imaginary axis eigenvalues of an Hamiltonian matrix. We show a similar connection between the singular values of a transfer function of a time-delay system and the imaginary axis eigenvalues of an infinite dimensional operator L <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ξ</sub> . Using spectral methods, this linear operator is approximated with a matrix. The approximate H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> norm of the time-delay system is calculated using the connection between the imaginary eigenvalues of this matrix and the singular values of a finite dimensional approximation of the time-delay system. Finally the approximate results are corrected by solving a set of equations which are obtained from the reformulation of the eigenvalue problem for L <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ξ</sub> as a finite dimensional nonlinear eigenvalue problem.
Hemochromatosis Mimicked Gaucher Disease: Role of Hyperferritinemia in Evaluation of a Clinical Case (2022)

Gaucher disease is a disorder of lysosomes caused by a functional defect of the glucocerebrosidase enzyme. The disease is mainly due to mutations in the GBA1 gene, which determines the gradual storage of glucosylceramide substrate in the patient's macrophages. In this paper, we describe the case of a 38-year-old man who clinically presented with hyperferritinemia, thrombocytopenia, leukopenia, anemia and mild splenomegaly; a diagnosis of hemochromatosis was made 10 years earlier. Re-evaluation of the clinical case led to a suspicion of Gaucher disease, which was confirmed by enzymatic analysis, which was found to be below the normal range, and genetic evaluation, which identified compound heterozygosity N370S/RecNciI. We know that patients suffering from Gaucher disease can also have high ferritin levels. Even if the mechanism underlying the changes in iron metabolism is not yet elucidated, the chronic mild inflammatory state present in these patients probably causes the storage of ferritin in macrophages, resulting in hyperferritinemia. Therefore, in the presence of few typical signs and symptoms of the disease should raise an alarm bell in the clinicians, inducing clinical suspicion of Gaucher disease. Misdiagnosis and diagnostic delay in metabolic diseases could cause irreversible organ damage and delay the start of specific therapy for these patients.