gebhart/patrepeval huggingface dataset:
Distribution of reduced‐nicotinamide‐adenine‐dinucleotide‐phosphate diaphorase‐positive cells and fibers in the cat central nervous system (1989)

Previous histochemical studies have suggested that reduced nicotinamide adenine dinucleotide phosphate (NADPH) diaphorase exists in distinct subsets of neurons that neither belong to a single transmitter type nor embrace all the neurons using a single transmitter. As a step toward establishing the role of this enzyme, the distribution of NADPH-diaphorase-positive neurons and fibers in the cat central nervous system was mapped by using a direct histochemical method. Heavily stained NADPH-diaphorase-positive neurons with many prominent cell processes were observed in the cerebral cortex, white matter, caudate nucleus, putamen, nucleus accumbens, septal nucleus, amygdala, anterior, lateral and posterior hypothalamic areas, dorsolateral part of the periaqueductal gray, superior colliculus, central tegmental field (Berman) (pedunculopontine tegmental area), dorsal tegmental nucleus, nucleus coeruleus, mesencephalic and pontine reticular formation, gigantocellular and magnocellular tegmental fields, nucleus facialis, and motor nucleus of the vagus. Moderately stained neurons with two or three prominent cell processes were observed in the nucleus of the diagonal band of Broca, globus pallidus, and substantia innominata. Medium-size, moderately stained neurons that had round large nuclei and no visible cell processes were found in the subthalamic nucleus, pontine gray, trapezoid body, and infratrigeminal, cochlear, and vestibular nuclei. Very dense NADPH-diaphorase-positive nerve terminal fields were seen in the olfactory tubercle, cortex, caudate nucleus, putamen, dentate gyrus, and interpeduncular nucleus. Intensely stained NADPH-diaphorase-positive nerve fibers were found in the stria terminalis, marginal region of the central tegmental field, dorsal tegmental nucleus, and spinal trigeminal tract as well as around the brachium conjunctivum. Although the staining of neurons and tracts was highly selective, they did not correspond to any single known neuronal or neurotransmitter type. Positive staining occurred in discrete subsets of neurons known to be associated with a variety of peptides and classical neurotransmitters. The functional significance of high NADPH diaphorase activity is unknown.
THE DISTRIBUTION OF HHV-8 LATENTLY INFECTED CELLS IN ALL STAGES OF KAPOSI'S SARCOMA (1999)

Cerimele, F.; Cesarman, E.; Curreli, F.; Hyjek, E.; Knowles, D. M.; Flore, O. Author Information
Methylated derivatives of pyrene and fluorene: Evaluation of genotoxicity in the hepatocyte/DNA repair test and tumorigenic activity in newborn mice (1987)

The genotoxicity of 1-methylpyrene, 1,6-dimethylpyrene, 1-methylfluorene, 9-methylfluorene, and 1,9-dimethylfluorene was evaluated in the hepatocyte primary culture/DNA repair test, and the tumorigenic potency of these compounds was tested by bioassay in newborn mice. With the exception of 1-methylfluorene, all of these methylated polycyclic aromatic hydrocarbons are known mutagens in Salmonella typhimurium. Both 1-methylpyrene and 1,6-dimethylpyrene induced unscheduled DNA synthesis in rat hepatocytes. However, only 1-methylpyrene was tumorigenic when administered to newborn male mice. None of the methylated fluorenes assayed in the hepatocyte primary culture/DNA repair test induced unscheduled DNA synthesis. While 1,9-dimethylfluorene exhibited weak tumorigenic activity when administered by subcutaneous injection to newborn mice, 1-methylfluorene and 9-methylfluorene were inactive.
A tobacco plasma membrane calmodulin‐binding transporter confers Ni2+ tolerance and Pb2+ hypersensitivity in transgenic plants (1999)

All organisms require a minimal amount of metal ions to sustain their metabolism, growth and development. At the same time, their intrinsic metal-uptake systems render them vulnerable to toxic levels of metals in the biosphere. Using radiolabeled recombinant calmodulin as a probe to screen a tobacco cDNA library, we have discovered a protein designated NtCBP4 (Nicotiana tabacum calmodulin-binding protein) that can modulate plant tolerance to heavy metals. Structurally, NtCBP4 is similar to vertebrate and invertebrate K+ and to non-selective cation channels, as well as to recently reported proteins from barley and Arabidopsis. Here we report on the subcellular localization of NtCBP4 and the phenotype of transgenic plants overexpressing this protein. The localization of NtCBP4 in the plasma membrane was manifested by fractionating tobacco membranes on sucrose gradients or by aqueous two-phase partitioning, and subsequently using immunodetection. Several independent transgenic lines expressing NtCBP4 had higher than normal levels of NtCBP4. These transgenic lines were indistinguishable from wild type under normal growth conditions. However, they exhibited improved tolerance to Ni2+ and hypersensitivity to Pb2+, which are associated with reduced Ni2+ accumulation and enhanced Pb2+ accumulation, respectively. To our knowledge this is the first report of a plant protein that modulates plant tolerance or accumulation of Pb2+. We propose that NtCBP4 is involved in metal uptake across the plant plasma membrane. This gene may prove useful for implementing selective ion tolerance in crops and improving phytoremediation strategies.
Morphological Changes in the Anterior Eye Segment after Long-Term Treatment with Different Receptor Selective Prostaglandin Agonists and a Prostamide (2003)

After one year of treatment with different prostaglandins and a prostamide, uveoscleral outflow pathways are enlarged and appear organized. Conventional outflow routes were also affected. Long-term treatment with AH13205, latanoprost, sulprostone, or bimatoprost also induces sprouting of nerve fibers.
EXTRACTIVES FROM POPULUS TREMULOÏDES HEARTWOOD: THE STRUCTURE AND SYNTHESIS OF TREMULONE (1962)

Tremulone, a dienone isolated from Populus tremuloïdes heartwood, has been shown to be stigmasta-3,5-diene-7-one. This has been confirmed by a partial synthesis from β-sitosterol. The possibility that tremulone might be an artifact arising from the isolation procedure is discussed.
Content-based gamut mapping algorithm for multiple engine printing (2009)

Gamut mapping is a critical process in the output color management of a printer. In systems consisting of two or more marking engines, these engines could in general have different output color gamuts. In special cases these gamuts can be drastically different. When applying gamut mapping to a multi-engine printing system, which gamut to use is not obvious. In the default case, i.e., if the multi-engine system is treated as a single engine with a single gamut, poor image quality could result. In this paper, we propose gamut mapping strategies for multiple engine printing, which depend on the relative importance of "color rendition" and "page-to-page color consistency" within a given document. In particular, we propose a content-based gamut mapping, wherein the trade-offs between color rendition and page-to-page color consistency can be automatically and dynamically made by segmenting the document and applying gamut mapping according to the needs of the segmented components.
On Idlow with Emphasis on Speculative SPICE Modeling (2006)

An empirical correlation model of Idlow, the MOSFET drain current measured at Vgs=Vdd/2 and Vds=Vdd, where Vdd is the supply voltage, is proposed based on the alphapower law model. It enables a comprehensive analysis of Idlow over a wide range of device geometry, supply voltage, and temperature in multi-threshold-voltage technologies. Built upon and verified by electrical-test data of 90nm partially-depleted (PD) silicon-on-insulator (SOI) technologies, the newly developed methodology provides practical and efficient guidelines to device target projection and target-based speculative SPICE model extraction.
Supplementary Figure 6 from AMG 757, a Half-Life Extended, DLL3-Targeted Bispecific T-Cell Engager, Shows High Potency and Sensitivity in Preclinical Models of Small-Cell Lung Cancer (2023)

&lt;p&gt;Supplementary Figure 6 A, Expression of human CD25, CD69, PD-1, and 4-1BB on human CD4+ T cells isolated from mouse lungs harboring SHP-77 tumors 168 hours after treatment with AMG 757 or a control HLE BiTE® molecule. B, Expression of human CD25, CD69, PD-1, and 4-1BB on human CD8+ T cells isolated from mouse lungs harboring SHP-77 tumors 168 hours after treatment with either AMG 757 or a control HLE BiTE® molecule. *P &lt; 0.05; **P &lt; 0.01; *** P&lt; 0.001;&lt;/p&gt;
ChemInform Abstract: SmI2‐Promoted Reformatsky‐Type Coupling Reactions in Exceptionally Hindered Contexts. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Flex to flex bonding using anisotropic conductive film for imaging systems (2014)

Bonding and integration technologies in ultrasound probes are challenging due to space limitations. Flexible substrates, with the benefits of being bendable, small and allows 3D integration, is an excellent choice for signal transferring in such systems. We have chosen to use anisotropic conductive film (ACF) as interconnection technology and the quality and the reliability of a flex-ACF-flex bonding have been studied. The relationship between bonding force and contact resistance have been characterized including the effect of thermal cycling tests and humidity tests. The study shows that flex-ACF-flex is a robust bonding technique which has very good performance also after environmental tests and is well suited for interconnection in ultrasonic transducer probes.
An Implantable 455-Active-Electrode 52-Channel CMOS Neural Probe (2013)

Neural probes have become the most important tool for enabling neuroscientists to place microelectrode sensors close to individual neurons and to monitor their activity in vivo. With such devices, it is possible to perform acute or chronic extracellular recordings of electrical activity from a single neuron or from groups of neurons. After the many developments in neural implants, it has become clear that large arrays of electrodes are desirable to further investigate the activity performed by complex neural networks. Therefore, in this paper, we propose a CMOS neural probe containing 455 active electrodes in the probe shank (100 μm wide, 10 mm long, and 50 μm thick) and 52 simultaneous readout channels in the probe body (2.9 × 3.3 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ). In situ amplification under each electrode enables low-impedance interconnection lines, regardless of the electrode impedance, with a residual crosstalk of -44.8 dB. This design has been implemented in a 0.18-μm standard CMOS technology, with additional CMOS-compatible post-processing performed at wafer level to define the electrodes and the probe outline. In this architecture, the analog front-end achieves an input-referred noise of 3.2 μV <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rms</sub> and an NEF of 3.08. The power consumption of the core circuit is 949.8 μW, while the total power consumption is 1.45 mW. The high-density active-electrode array in this neural probe allows for the massive recording of neural activity. In vivo measurements demonstrate successful simultaneous recordings from many individual cells.
Etude des Fractions Glycériques et des phospholipides de trois types d’arachides (Arachis hypogaea) (2017)

In view of diversification of the congolese economy on the hand and of source of lipids consumed on the other hand in Congo, it has been achieved a survey of the glyceride fraction of oils extracted from the seeds of peanuts of Lekana in the trays region and of Manga in pan region, two departments of Congo-Brazzaville. These profiles have been compared to the one gotten from the seeds of peanuts of sudan sold on the market of Toulouse in France. 
The total fat acids of the three samples present the identical caracteritics of which the main are the oleic acid (C18:1), linoleic acid (C18:2) and palmitic acid (C16;0). 
The glycerique fraction is mostly dominated by the triglycerides as in the other oleaginous seeds. The contents in mono, di and triglycerides are influenced by the contents in fat acids of the different samples. These profiles confer to these oils the statute of the frying oils and can be useful in hair oils, in pharmacy or in other domains.
The phospholipids of the three samples present the identical caracteritics. All classes of the phospholipids are presents. The oil from Manga peanut seeds are poor in phosphatidylcholins after the oil from Lekana peanut seeds.
Plating Stresses from Electroless Nickel Deposition on Beryllium (1969)

Commercial electroless nickel coatings on beryllium are shown to produce residual stresses of appreciable magnitude at the coating‐substrate interface. A 0.005‐in. layer of electroless nickel deposited on one side of a 0.010‐in. beryllium strip induced residual compressive stresses in the beryllium substrate as high as 33,000 psi as calculated from the curvature of the plated composite. Evidence is presented to indicate that at least a substantial part of this residual stress is the result of a solid‐state reaction and accompanying volume change in the coating during normal stress‐relief annealing of the composite near 200°C. This is believed to be an ordering reaction associated with formation of the precipitate phase. The effect of temperature change on the level of induced stress in a nickel‐beryllium composite due to a difference in coefficients of thermal expansion was investigated. The net difference in coefficients of thermal expansion increased in the temperature range 25°–50°C to a maximum value of , and then decreased approximately linearly up to 200°C at a rate of .
Ionic Liquid-Promoted Regiospecific Friedlander Annulation:  Novel Synthesis of Quinolines and Fused Polycyclic Quinolines (2003)

Several room-temperature ionic liquids (ILs) based on 1-butylimidazolium salts with varying anions were synthesized and evaluated for the preparation of biologically active substituted quinolines and fused polycyclic quinolines using the Friedlander heteroannulation reaction. On screening, 1-butylimidazolium tetrafluoroborate [Hbim]BF4 was found to be the best ionic liquid for the heteroannulation reaction, and the reasons to this effect are well explained. The reactions proceed very well under relatively mild conditions without any added catalyst. The IL acts as a promoter for this regiospecific synthesis and can be recycled. By this green approach, various quinolines were prepared in excellent yields and purity and well-characterized.
Supplementary Figure S2 from NAP1051, a Lipoxin A4 Biomimetic Analogue, Demonstrates Antitumor Activity Against the Tumor Microenvironment (2023)

&lt;p&gt;Figure S2 shows the direct cytotoxicity of NAP1051 and the relative tumor volume of the HCT116 model.&lt;/p&gt;
Battery-enabled anti-theft vehicle immobilizer (2022)

Auto thieves often exploit the cyber vulnerabilities of existing key/phone-based vehicle immobilizers. To prevent this exploitation of cyber vulnerabilities for auto thefts, we present Battery Sleuth (Bleuth), a novel "physical" vehicle immobilizer which is immune to the common cyber-attack vectors - avoiding the use of wireless communication between key/phone and vehicle as well as in-vehicle networks. Bleuth achieves this by using the common 12V vehicle batteries to authenticate the driver with encrypted power-line communication and then control the battery's output power based on the authentication results, hence (im)mobilizing the vehicle without requiring drivers to carry any additional token. Bleuth is also equipped with four alarms to detect, and respond to, illegitimate operations (i.e., theft attempts), including attempts of unauthorized cranking of the engine, removal/shorting of the authenticator from the battery, abuse of the PLC to drain the car battery, and removal of the dongle from the auxiliary power outlet. Bleuth recharges its power supply automatically to free drivers from the maintenance burden. We have prototyped Bleuth as an add-on module that can be installed on commodity vehicles and evaluated it via field tests on 8 vehicles. We have also demonstrated Bleuth's utility and effectiveness via a survey of 612 car owners.
Airgap Interconnects: Modeling, Optimization, and Benchmarking for Backplane, PCB, and Interposer Applications (2014)

Frequency and time domain models are developed for backplane (BP), printed circuit board (PCB), and silicon interposer (SI) links using six-port transfer matrices (ABCD matrices) for bumps, vias and connectors, and coupled multiconductor transmission lines for traces. The six-port transfer matrix approach enables easy computation of the transfer function, as well as near-end and far-end crosstalk. The intersymbol interference is accounted for by computing the pulse response for the worst case bit pattern. Furthermore, the models developed here are used to optimize the data-rate and trace width for each of the links, so that the aggregate bandwidth obtained per joule of energy supplied to the link is maximized. The modeling and optimization approach developed here serves as a good platform to compare the air-gap interconnects against BP, PCB, and SI interconnects on lossy dielectrics. It is shown that air-gap interconnects can provide an aggregate bandwidth improvement of 3x-4x for BP links at a comparable energy per bit, and a 5x-9x improvement in aggregate bandwidth of PCB links at the expense of 20% higher energy per bit. For SI links, airgap interconnects are shown to provide a 2x-3x improvement in aggregate bandwidth and a 1x-1.5x improvement in energy per bit.
Motion Correction for Coronary Stent Reconstruction From Rotational X-ray Projection Sequences (2007)

This paper presents a new method for 3-D tomographic reconstruction of stent in X-ray cardiac rotational angiography. The method relies on 2-D motion correction from two radiopaque markerballs located on each side of the stent. The two markerballs are on a guidewire and linked to the balloon, which is introduced into the artery. Once the balloon has been inflated, deflated, and the stent deployed, a rotational sequence around the patient is acquired. Under the assumption that the guidewire and the stent have the same 3-D motion during rotational acquisition, we developed an algorithm to correct cardiac stent motion on the 2-D X-ray projection images. The 3-D image of the deployed stent is then reconstructed with the Feldkamp algorithm using all the available projections. Although the correction is an approximation, we show that the intrinsic geometrical error of our method has no visual impact on the reconstruction when the 2-D markerball centers are exactly detected and the markerballs have the same 3-D motion as the stent. Qualitative and quantitative results on simulated sequences under different realistic conditions demonstrate the robustness of the method. Finally, results from animal data acquired on a rotational angiography device are presented.
Time Dispersion and Delay Spread Estimation for Adaptive OFDM Systems (2008)

Time dispersion is one of the most important characteristics of the wireless channel. The knowledge about the time dispersion of a channel can be used to design better systems that can adapt themselves to the changing nature of the transmission medium. In this paper, algorithms to estimate the time dispersion (frequency selectivity) of the channel, which use the frequency-domain channel estimates or the frequency-domain-received signal, are proposed. The proposed algorithms estimate the power delay profile (PDP) from which the two important dispersion parameters, namely root-mean-squared (RMS) delay spread and maximum excess delay of the channel, are estimated. It is shown that synchronization errors bias the performance of the estimators based on the channel correlation, and this bias is removed by obtaining the PDP using the magnitude of the channel estimates. Moreover, the Cramer-Rao lower bound (CRLB) for the estimation of the RMS delay spread is derived, and the performances of the proposed algorithms are compared against this theoretical limit.
Developing a Low-Cost, High Performance, SDR-Based Local Positioning System (2021)

This paper explored the development of software-defined radio (SDR) based alternative positioning, navigation and timing (PNT), independent of any Global Navigation Satellite System (GNSS) for use in GNSS-denied areas. A navigation signal architecture based on GPS L1C signal was designed and broadcasted on a network of SDR-based transmitters. Signals were processed by a moving receiver which used a MATLAB-based software receiver to successfully estimate changes in range to each of the transmitters.
A novel chemically, thermally and electrically robust Cu interconnect structure with an organic non-porous ultralow-k dielectric fluorocarbon (k=2.2) (2012)

A novel chemically, thermally and electrically robust Cu damascene interconnects with an organic non-porous ultralow-k (ULK) dielectric fluorocarbon (k=2.2), deposited by an advanced microwave excited plasma enhanced CVD, is demonstrated. A practical nitrogen plasma treatment (NPT) was employed to minimize chemically damage introduction to fluorocarbon in post-etching cleaning and CMP processes. Also, a new structure with a delamination-protective-liner (DPL), instead of barrier-metal, between Cu and fluorocarbon is introduced to avoid thermally induced electrical degradation and to reduce the interconnect delay significantly (by >;30% in 32 nm-node). Non-porous ULK fluorocarbon with NPT and DPL technologies is a promising candidate for high performance Cu interconnects.
Effect of dietary selenium on the reproductive success of bluegills (Lepomis macrochirus) (1993)

Abstract The effects of dietary and waterborne selenium on the reproductive success of adult bluegills were evaluated in a chronic toxicity study. Before spawning, two-year-old bluegills were exposed for 60 d to six combinations of dietary and waterborne selenium. Mean seleno-L-methionine (as selenium) concentrations measured in the diet were 0.8 (control), 4.6, 8.5, 16.8, and 33.3 μg/g (dry weight). Waterborne selenium was supplied as a 6:1 mixture of selenate and selenite. Nominal waterborne selenium exposure concentration was 10 μg/L in all exposures except the control. Morphological measurements of adult fish, including length, weight, condition factor, and Gonado Somatic Index, were measured at days 60 and 140 of exposure. Reproductive indicators, including spawning frequency, number of eggs per spawn, percentage of hatch, and survival of resulting fry for 30 d after hatch were monitored during the 11-week spawning period. Selenium concentrations were determined in adult fish, eggs, and 30-d-old fry. Only fry were significantly affected. Survival was severely reduced in fry of parents exposed to 10 μg/L waterborne selenium in combination with dietary exposure of 33.3 μg/g (dry weight) seleno-L-methionine. These results support field observations that indicate food-chain accumulation of selenium can severely reduce reproductive success of bluegills.