gebhart/patrepeval huggingface dataset:
Dynamics of hot QCD matter — Current status and developments (2022)

The discovery of hot and dense quantum chromodynamics (QCD) matter, known as Quark–Gluon Plasma (QGP), is an essential milestone in understanding the finite temperature QCD medium. Experimentalists around the world collect an unprecedented amount of data in heavy ion collisions, at Relativistic Heavy Ion Collider (RHIC), at Brookhaven National Laboratory (BNL) in New York, USA, and at the Large Hadron Collider (LHC), at CERN in Geneva, Switzerland. The experimentalists analyze these data to unravel the mystery of this new phase of matter that filled a few microseconds old universe just after the Big Bang. Recent advancements in theory, experimental techniques, and high computing facilities help us to better interpret experimental observations in heavy ion collisions. The exchange of ideas between experimentalists and theorists is crucial for the characterization of QGP. The motivation of this first conference, named Hot QCD Matter 2022 is to bring the community together to have a discourse on this topic. In this paper, there are 36 sections discussing various topics in the field of relativistic heavy ion collisions and related phenomena that cover a snapshot of the current experimental observations and theoretical progress. This paper begins with the theoretical overview of relativistic spin-hydrodynamics in the presence of the external magnetic field, followed by the Lattice QCD results on heavy quarks in QGP. Finally, it concludes with an overview of experimental results.
Supplemental Figures S1-2 from The BET Bromodomain Inhibitor OTX015 Affects Pathogenetic Pathways in Preclinical B-cell Tumor Models and Synergizes with Targeted Drugs (2023)

&lt;p&gt;Supplemental Figures S1-2. Supplemental Figures S1: effects of OTX015 on cell cycle and cell growth in DLBCL cell lines. Supplemental Figures S2: effects of OTX015 on apoptosis in DLBCL cell lines.&lt;/p&gt;
Retrieving atmospheric aerosol parameters on the base of multiwavelength lidar and sun sky-scanning radiometer data (2003)

A flexible algorithm to commonly process lidar and sun sky-scanning radiometer measurements is developed. The algorithm is oriented towards the engineering facilities of the radiometer CIMEL used by AERONET network and a two-to-four wavelength lidar used by European lidar network EARLINET. Numerical experiments were performed to assess algorithm sensitivity to measurement errors and possible violations of basic model assumptions.
Amorphous In–Ga–Zn–O thin‐film transistors prepared by magnetron sputtering using Kr and Xe instead of Ar (2013)

Abstract Heavier noble gases Kr and Xe instead of the lighter Ar during the magnetron‐sputtering deposition of amorphous indium–gallium–zinc oxide films are introduced in fabricating their thin‐film transistors (TFTs). Heavy noble gases can reduce damage to film induced by ion bombardment during the sputtering depositions. Higher field‐effect mobility with better gate bias stability can be obtained in the heavier‐noble‐gas sputtered TFTs. Raman spectroscopic analysis and X‐ray reflectometry respectively suggest that the disordered structure in the film is suppressed, and the film becomes denser by introducing heavy noble gases, corresponding to the improvement of TFT performance.
Developing a flexible model of electron scattering in solid for charging analysis (2018)

We have been developing a charging simulator “CHARMs”, which is based on 3D finite element method, to predict the characteristics of signal from charged pattern on surface of semi-conductor during the SEM observation. We have constructed a new flexible model to simulate the in-solid electron scattering by the Langevin equation for “CHARMs”. Our new model can manipulate the size of the diffusion cloud of scattering electron by the parameters of it and calculate ten times faster than the conventional Monte Carlo (MC) method. In addition to that, the model has the possibility to accurately describe the scattering of low energy electron. We also confirmed that the same results of the conventional MC method can be obtained from the simulation model of metal pattern buried in the sample.
ChemInform Abstract: Synthesis, Biological Activity and Decomposition Studies of Amino Acid Phosphomonoester Amidates of Acyclovir. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Immunogenicity and specificity of Norovirus Consensus GII.4 virus-like particles in monovalent and bivalent vaccine formulations (113.27) (2012)

Abstract Noroviruses, a major cause of acute gastroenteritis worldwide, present antigenic diversity that must be considered for the development of an effective vaccine. In this study, we explored approaches to increase the broad reactivity of virus-like particle (VLP) norovirus vaccine candidates. The immunogenicity of a GII.4 “Consensus” VLP that was engineered from sequences of three distinct naturally-occurring GII.4 strains was examined for its ability to induce cross-reactive immune responses against different noroviruses. Rabbits immunized with GII.4 Consensus VLPs developed high serum antibody titers against VLPs derived from a number of distinct wild-type GII.4 viruses Because the sera exhibited low cross-reactivity with antigenically-distinct GI norovirus strains, we investigated the serum antibody response to a bivalent vaccine formulation containing GI.1 and GII.4 Consensus VLPs that was administered to animals under varying conditions. In these studies, the highest homologous and heterologous antibody titers to the bivalent vaccine were elicited following immunization of animals by the IM route using Alhydrogel as adjuvant. Our data indicate that the use of both genetically-engineered norovirus VLPs that incorporate relevant epitopes from multiple strains and multivalent vaccine formulations increase the breadth of the immune response to diverse variants within a genotype and, thus, prove helpful in the rational design of VLP-based vaccines against human noroviruses.
Molecular Magnetic Resonance Imaging of Coronary Thrombosis and Pulmonary Emboli With a Novel Fibrin-Targeted Contrast Agent (2005)

Molecular MR imaging with the fibrin-targeted contrast-agent EP-2104R allows selective visualization of acute coronary, cardiac, and pulmonary thrombi.
Improved reliability and switching performance of atom switch by using ternary Cu-alloy and RuTa electrodes (2012)

For the first time, Cu(AlTi)-alloy active-electrode coupled with RuTa inert-electrode is proposed to improve the reliability of nonvolatile Cu atom switch. The remarkably high rupture temperature (T <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r</sub> >400 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">o</sup> C) of the nanometer-scale Cu bridge with the high thermal resistance (R <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sub> ) is realized by the Cu-alloy without increasing programming current. The anti-Cu diffusive, RuTa-alloy improves the retention of the ON-state at 150 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">o</sup> C and endurance to >10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sup> cycles. The metallurgical prescription is a key to improve the reliability and switching performance of the conducting bridge.
SQUID based resistance bridge for shot noise measurement on low impedance samples (1999)

We present a resistance bridge which uses a SQUID to measure the shot noise in low impedance samples. The experimental requirements are high DC bias currents (typically 10mA) together with high AC sensitivity (pA/VHz). This system is used to investigate the shot noise in Superconductor/Normal/Superconductor junctions where Andreev reflection enhanced shot noise is expected. Because our setup has an intrinsic noise much smaller than the thermal noise of the resistance bridge at 4.2K, reliable results can be obtained on impedances out of the range of classical measurement schemes.
Metabolite therapy guided by liquid biopsy proteomics delays retinal neurodegeneration (2019)

Abstract Neurodegenerative diseases are debilitating, incurable disorders caused by progressive neuronal cell death. Retinitis pigmentosa (RP) is a blinding neurodegenerative disease that results in retinal photoreceptor cell death and progresses to the loss of the entire neural retinal network. We previously found that proteomic analysis of the adjacent vitreous serves as way to indirectly biopsy the neural retina and identify changes in the retinal proteome. We therefore analyzed protein expression in liquid vitreous biopsies from autosomal recessive retinitis pigmentosa (arRP) patients with PDE6A mutations and arRP mice with Pde6ɑ mutations. Proteomic analysis of retina and vitreous samples identified molecular pathways affected at the onset of photoreceptor cell death. Based on affected molecular pathways, arRP mice were treated with a ketogenic diet or metabolites involved in fatty-acid synthesis, oxidative phosphorylation, and the tricarboxylic acid (TCA) cycle. Dietary supplementation of a single metabolite, ɑ-ketoglutarate, increased docosahexaeonic acid (DHA) levels, provided neuroprotection, and enhanced visual function in arRP mice. A ketogenic diet delayed photoreceptor cell loss, while vitamin B supplementation had a limited effect. Finally, desorption electrospray ionization mass spectrometry imaging (DESI-MSI) revealed restoration of key metabolites that correlated with our proteomic findings: pyrimidine and purine metabolism (uridine, dihydrouridine, and thymidine), glutamine and glutamate (glutamine/glutamate conversion), and succinic and aconitic acid (TCA cycle). This study demonstrates that replenishing TCA cycle metabolites via oral supplementation prolongs vision and provides a neuroprotective effect on the photoreceptor cells and inner retinal network. One Sentence Summary The study shows protein and metabolite pathways affected during neurodegeneration and that replenishing metabolites provides a neuroprotective effect on the retina.
Electrical Resistivity Tomography (ERT) as a tool for the assessment of karst features in carbonate aquifers. (2016)

International audience
Neutral and Cationic Methyl Complexes of Platinum(II) with 6-Substituted 2,2′-Bipyridines: Synthesis, Characterisation and Reactivity with Carbon Monoxide − Molecular Structures of [PtCl(methyl)(6-ethyl-2,2′-bipyridine)] and of [Pt(methyl)(acetonitrile)(6-ethyl-2,2′-bipyridine)][BF4] (2000)

The complex trans-[PtCl(Me)(SMe2)2] reacts with 6-R-substituted 2,2′-bipyridine, HLn (n = 1, R = H; n = 2, R = Me; n = 3, R = Et; n = 4, R = iPr; n = 5, R = CH2Ph; n = 7, R = Ph), to afford the neutral complexes [PtCl(Me)(HLn)]. Only one isomer is formed (R cis to Cl) with all the ligands, but one (R = Ph). When R = C(Me)2Ph (HL6), only an (N−N−C) cyclometallated species is formed. The stereoselectivity observed is interpreted in terms of the nature of the substituent R, and of the hydrogen bond formed between H−C(α) of the R substituent and the chloride ion bound to the platinum center. The molecular structure of [PtCl(Me)(HL3)] has been resolved by an X-ray analysis and shows that the above-mentioned hydrogen bond length is 2.28 Å. The reactivity of three representative complexes (R = H, Et, CH2Ph) with carbon monoxide has been studied. The reaction affords the ionic species [Pt(Me)(CO)(HLn)]+[PtCl2(Me)(CO)]− and the free ligand. There is evidence of the formation of an acyl species, which does not contain the bipyridine ligand, only when working at high pressures of CO. The above cations are also obtained by direct carbonylation of the solvent species, [Pt(Me)(MeCN)(HLn)][BF4], achieve by halide abstraction from the neutral complexes. The molecular structure of [Pt(Me)(MeCN)(HL3)][BF4] has been resolved by an X-ray analysis.
Shoulder disability and late symptoms following surgery for early breast cancer (2008)

Shoulder disability seems to be a frequent late complication to the treatment of early breast cancer (35%). When equal axillary dissection and radiation therapy had been applied, BCT patients were found to suffer less frequent from this complication than patients treated with mastectomy.
High-Transmission Neutron Optical Devices Utilizing Micro-Machined Structures (2023)

Neutrons are a powerful probe in material science with unique penetrating abilities. A major challenge stems from the fact that neutron optical devices are limited to refractive indices on the order of n≈1±10−5. By exploiting advances in precision manufacturing, we designed and constructed micro-meter period triangular grating with a high-aspect ratio of 14.3. The manufacturing quality is demonstrated with white-light interferometric data and microscope imaging. Neutron-scattering experiment results are presented, showing agreement with refraction modelling. The capabilities of neutron Fresnel prisms and lenses based on this design are contrasted with existing neutron focusing techniques, and the path separation of a prism-based neutron interferometer is estimated.
Turner Syndrome (1994)

Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy. Subscribe to eTOC Secondary Logo Journal Logo All Articles Images Videos Podcasts Blogs Advanced Search Toggle navigation Subscribe Register Login HomeCurrent IssuePrevious Issues Current Opinion in Endocrinology, Diabetes and ObesityThe Endocrinologist (1991 - 2010) Published Ahead-of-PrintFor Authors Information for AuthorsLanguage Editing Services Journal Info About the JournalEditorial BoardAdvertisingOpen AccessSubscription ServicesReprintsRights and PermissionsMobileNew Features All Articles Images Videos Podcasts Blogs Advanced Search
Wettability Alteration of Carbonate Rock by Chelating Agents (2023)

Abstract The two most important EOR mechanisms for oil-wet carbonate rock are IFT reduction and wettability alteration. By altering rock surface wettability, the resulting positive capillary pressure can help imbibe water and displace oil from the rock matrix. Researchers have studied the wettability alteration of materials covering surfactants, nanofluids, alkalis, salts, and so on. Chelating agents are found to alter carbonate rock wettability recently. This work aims at the wettability alteration and EOR production by three chelating agents in different salinity condition when used alone or combined with surfactants. Three commonly used chelating agents were studied. Indiana limestone and Guelph dolomite were selected to represent carbonate rocks. Rock samples were dipped in chelating agent solutions at different concentrations and salinity, in ambient and reservoir conditions. Differences in contact angle values due to the treatment reflect the wettability alteration performance. Mixtures of chelating agents and surfactants (VES AGA-97, gemini surfactant) were prepared and tested in the spontaneous imbibition study. Results show that all tested chelating agents could strongly alter the wettability of carbonate samples from oil-wet to water-wet at relatively low concentrations (~0.4 wt%). When salinity increased, however, higher concentrations were required. Salts showed different effects on the wettability alteration by DTPA. The negative effect lowered in the sequence: NaHCO3 &amp;gt; Na2SO4 ≈ NaCl ≈ MgCl2. CaCl2 showed a positive effect, indicating enhanced performance in carbonate formations due to the abundant Ca2+ ions. A real-time contact angle study under reservoir conditions revealed that the oil drop decreased in diameter while increasing in height, indicating a higher tendency to be removed from the rock surface. The gemini surfactant + DTPA mixture has stronger wettability alteration potential. The VES + DTPA mixture has a stronger IFT reduction potential. The spontaneous imbibition results showed that for relatively tight carbonate rock, wettability alteration has a higher significance than IFT reduction. This study shows the outstanding wettability alteration performance of chelating agents, suggesting possible applications in oil-wet carbonate formations with high salinity. Besides, this study suggests that in low permeability formations, wettability alteration contributes more to oil recovery than IFT reduction.
No Evidence of an Effect of Alterations in Dietary Fatty Acids on Fasting Adiponectin Over 3 Weeks (2008)

Fasting serum adiponectin was not detectably affected by alterations in dietary fatty acid profile in mildly hyperlipidemic men. There was no evidence that an increase in SFA content of the diet significantly worsened fasting serum adiponectin over a 3-week intervention period.
Unique molecular surface features ofin vivotolerized T cells (1998)

Differential expression of surface markers can frequently be used to distinguish functional subsets of T cells, yet a surface phenotype unique to T cells induced into an anergic state has not been described. Here, we report that CD4 T cells rendered anergic in vivo by superantigen can be identified by loss of the 6C10 T cell marker. Inoculation of Vbeta8.1 T cell antigen receptor (TCR) transgenic mice with a Vbeta8.1-reactive minor lymphocyte-stimulating superantigen (Mls-1(a)) induces tolerance to Mls-1(a) by clonal anergy. CD4 lymph node T cells from Mls-1(a) inoculated transgenic mice enriched for the 6C10(-) phenotype neither proliferate nor produce interleukin-2 upon TCR engagement, whereas 6C10(+) CD4 T cells retain responsiveness. Analysis of T cell memory markers demonstrate that 6C10(-) T cells remain 3G11(hi) but express heterogeneous levels of CD45RB, CD62L, CD44, and the CD69 early activation marker, suggesting that T cells at various degrees of activation can be functionally anergic. These studies demonstrate that anergic T cells can be purified based on 6C10 expression permitting examination of issues concerning biochemical and biological features specific to T cell anergy.
Effects of Annurca Flesh Apple Polyphenols in Human Thyroid Cancer Cell Lines (2022)

Among natural macromolecules, the polyphenol extract from <i>Annurca</i> flesh (<i>A</i>FPE) apple could play a potential therapeutic role for a large spectrum of human cancer also by exerting antioxidant properties. Thyroid cancer is a common neoplasia in women, and it is in general responsive to treatments although patients may relapse and metastasize or therapy-related side effects could occur. In this study, we explored the effects of <i>A</i>FPE on papillary (TPC-1) and anaplastic (CAL62) thyroid cancer cell line proliferation and viability. We found that <i>A</i>FPE exposure induced a reduction of cell proliferation and cell viability in dose-dependent manner. The effect was associated with the reduction of phosphorylation of Rb protein. To study the mechanisms underlying the biological effects of <i>A</i>FPE treatment in thyroid cancer cells, we investigated the modulation of miRNA (miR) expression. We found that <i>A</i>FPE treatment increased the expression of the miR-141, miR-145, miR-200a-5p, miR-425, and miR-551b-5p. Additionally, since natural polyphenols could exert their beneficial effects through the antioxidant properties, we investigated this aspect, and we found that <i>A</i>FPE treatment reduced the production of reactive oxygen species (ROS) in CAL62 cells. Moreover, <i>A</i>FPE pretreatment protects against hydrogen peroxide-induced oxidative stress in thyroid cancer cell lines. Taken together, our findings suggest that <i>A</i>FPE, by acting at micromolar concentration in thyroid cancer cell lines, may be considered a promising adjuvant natural agent for thyroid cancer treatment approach.
Effect of Exogenous Growth Hormone in Early and Late Lactation on Lactational Performance of Dairy Cows (1983)

Bovine growth hormone (51.5 IU/day) and placebo injections were administered for 10 days to four Holstein cows in early lactation (wk 12) and again in late lactation (wk 35). Milk productions in the last 5 days of each period were compared. In early lactation, growth hormone increased milk yield by 15%, fat yield by 17%, protein yield by 14%, and lactose yield by 21%. In late lactation the respective increases were 31, 42, 18, and 35%. For responses of early and late lactation to growth hormone on a quantitative basis, increases for milk yield (4.3 versus 3.9 kg/day) and milk energy secretion (3.3 versus 3.4 Mcal/day) were similar. Concurrent with these increased milk yields, ad libitum intakes of a complete mixed diet declined during the period of growth hormone treatment by 3% in early lactation and 16% in late lactation. During the 6 h immediately following injections of growth hormone, blood plasma concentrations of growth hormone were elevated about 400% in early lactation and 700% in late lactation. Concentrations in plasma of free fatty acids were also higher during growth hormone treatment in late lactation but not in early lactation. Treatments did not affect plasma concentrations of glucose,
Bounds of mmWave-Based Ranging and Positioning with Massive Uniform Rectangular Array (2018)

This paper aims at investigating the feasibility of ranging and positioning in millimeter (mm)-level accuracy by adopting millimeter-wave and 3D massive antenna array. The agent is equipped with massive phased uniform rectangular array (URA) and multiple anchors are considered in localization networks to pursue a higher accuracy, where a far-field environment is assumed for phased massive URA. Fundamental limits of both time-based ranging and positioning are derived by Crámer-Rao bound (CRB), where the relationship between the fundamental bound of range estimation and that of position estimation is theoretically clarified. Numerical results show that the proposed scenario achieves a precise mm-level accuracy for ranging and positioning.
Cluster adaptive training of average voice models (2014)

Hidden Markov model based text-to-speech systems may be adapted so that the synthesised speech sounds like a particular person. The average voice model (AVM) approach uses linear transforms to achieve this while multiple decision tree cluster adaptive training (CAT) represents different speakers as points in a low dimensional space. This paper describes a novel combination of CAT and AVM for modelling speakers. CAT yields higher quality synthetic speech than AVMs but AVMs model the target speaker better. The resulting combination may be interpreted as a more powerful version of the AVM. Results show that the combination achieves better target speaker similarity when compared with both AVM and CAT while the speech quality is in-between AVM and CAT.