gebhart/patrepeval huggingface dataset:
Remote 3D medical consultation (2005)

Two-dimensional (2D) video-based telemedical consultation has been explored widely in the past 15-20 years. Two issues that seem to arise in most relevant case studies are the difficulty associated with obtaining the desired 2D camera views, and poor depth perception To address these problems we are exploring the use of a small array of cameras to reconstruct a real-time, on-line 3D computer model of the real environment and events. We call this 3D medical consultation (3DMC). The idea is to give remote users what amounts to an infinite set of stereoscopic viewpoints, simultaneously addressing the visibility and depth perception problems associated with 2D video. Here we describe our current prototype system, some of the methods we use, and some early experimental results
Peroxisome Proliferator-activated Receptor γ Agonists Inhibit HIV-1 Replication in Macrophages by Transcriptional and Post-transcriptional Effects (2002)

Previous studies have demonstrated that cyclopentenone prostaglandins (cyPG) inhibit human immunodeficiency virus type 1 (HIV-1) replication in various cell types. We investigated the role of PG in the replication of HIV-1 in primary macrophages. The cyPG, PGA(1) and PGA(2), inhibited HIV-1 replication in acutely infected human monocyte-derived macrophages (MDM). Because PGA(1) and PGA(2) have previously been shown to be peroxisome proliferator-activated receptor gamma (PPARgamma) agonists, we examined the effect of synthetic PPARgamma agonists on HIV replication. The PPARgamma agonist ciglitazone inhibited HIV-1 replication in a dose-dependent manner in acutely infected human MDM. In addition, cyPG and ciglitazone reduced HIV replication in latently infected and viral entry-independent U1 cells, suggesting an effect at the level of HIV gene expression. Ciglitazone also suppressed HIV-1 mRNA levels as measured by reverse transcriptase PCR, in parallel with the decrease in reverse transcriptase activity. Co-transfection of PPARgamma wild type vectors and treatment with PPARgamma agonists inhibited HIV-1 promoter activity in U937 cells. Activation of PPARgamma also decreased HIV-1 mRNA stability following actinomycin D treatment. In summary, our experimental findings implicate PPARgamma as an important factor in the suppression of HIV-1 gene expression in MDM by cyPG. Thus natural and synthetic PPARgamma agonists may play a role in controlling HIV-1 infection in macrophages.
Facile, catalyst-free, microwave-assisted access toward the synthesis of 2-aryl/alkyl-3-(1H-benzo[d]imidazol-2-yl)-2, 3-dihydroquinazolin-4(1H)-ones (2017)

An efficient, catalyst-free, microwave-assisted approach has been developed for the synthesis of 2-aryl/alkyl-3-(1H-benzo[d]imidazol-2yl)-2,3-dihydroquinazolin-4(1H)-one derivatives by condensing 2-aminobenzamides with various aliphatic, aromatic, and heterocyclic aldehydes. This catalyst-free approach exhibited good functional group compatibility and produced the desired products in good to excellent yields in just 10-20 min. This approach can be seen as a better alternative of the metal-catalyzed protocols used for the synthesis of this class of compounds. The formation of desired compound has also been confirmed by X-ray analysis.
GHz modulation enabled using large extinction ratio waveguide-modulator integrated with 404 nm GaN laser diode (2016)

A 404-nm emitting InGaN-based laser diode with integrated-waveguide-modulator showing a large extinction ratio of 11.3 dB was demonstrated on semipolar (2021) plane GaN substrate. The device shows a low modulation voltage of -2.5 V and ~ GHz -3 dB bandwidth, enabling 1.7 Gbps data transmission.
Self-aligned optical connector assembly on polymer waveguide integrated package substrate for co-packaged optics (2023)

For an advanced co-packaged optics, we proposed the active-optical package substrate (AOP substrate), which is a Si-photonics-embedded package substrate with single-mode polymer-waveguide optical redistribution. In this work, we demonstrated a self-aligned optical connector assembly for the AOP substrate using a thin mechanical guiding structure less than <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$10-\mu \mathrm{m}$</tex> thickness. As a result, low-loss optical characteristics of 1-dB penalty was obtained for the assembled connector.
Search for FCNC single top-quark production at s=7 TeV with the ATLAS detector (2012)

A search for the production of single top-quarks via flavour-changing neutral-currents is presented. Data collected with the ATLAS detector at a centre-of-mass energy of s=7 TeV, corresponding to an integrated luminosity of 2.05 fb−1, are used. Candidate events with a semileptonic top-quark decay signature are classified as signal- or background-like events by using several kinematic variables as input to a neural network. No signal is observed in the neural network output distribution and a Bayesian upper limit is placed on the production cross-section. The observed upper limit at 95% confidence level on the cross-section multiplied by the t→Wb branching fraction is measured to be σqg→t×B(t→Wb)<3.9 pb. This upper limit is converted using a model-independent approach into upper limits on the coupling strengths κugt/Λ<6.9⋅10−3 TeV−1 and κcgt/Λ<1.6⋅10−2 TeV−1, where Λ is the new physics scale, and on the branching fractions B(t→ug)<5.7⋅10−5 and B(t→cg)<2.7⋅10−4.
A New UWB Synchronization Scheme Using Multipath Components Jointly (2008)

In ultra-wideband (UWB) systems, conventionally, the synchronization is to align time phases of a locally generated template and any of multipath components to within an allowable range. However, the synchronization with a low-power multipath component could incur significant performance degradation in receiver operation (e.g., detection) after the synchronization. On the other hand, the synchronization with a high-power multipath component can improve the performance in receiver operation after the synchronization. Generally, the first one among multi- path components has the largest power. Thus, the synchronization with the first path component can make better performance than that with a low-power component in receiver operations after the synchronization. Based on which, we first propose an optimal decision rule based on a maximum likelihood (ML) approach, and then, develope a simpler suboptimal decision rule for selecting the first path component. Simulation results show that the optimal and suboptimal decision rules have better performance than the conventional decision rule in UWB multipath channels.
Massilia timonae as cause of chronic endophthalmitis following cataract surgery (2015)

No author has a financial or proprietary interest in any material or method mentioned.
Analysis of Periodical Structures Produced by Laser Interference Structuring Using Energy Dispersive X-ray Spectrometry (2006)

Abstract Laser Interference Metallurgy is a newly developed method which permits the creation of periodic patterns with a well defined long-range order on metallic surfaces. By means of interfering laser beams with sufficient high pulse power a direct structuring on the scale of microns with well known metallurgical effects such as melting, recrystallization, quenching, recovery, defect or phase formation can be obtained. In this work Energy Dispersive X-ray Spectroscopy is used to study the constitutive elements of the films at different irradiated zones. The obtained scans are compared with cross-sectional analyses by Focused Ion Beam giving important information for the interpretation of the layer structure.
METHANE GAS STABILIZES SUPERCOOLED ETHANE DROPLETS IN TITAN'S CLOUDS (2010)

ISSN:1967-2014
<title>SHRIMP: shallow-water real-time imaging polarimeter</title> (1999)

Through the use of novel imaging devices called Polarization Cameras polarization vision can be attained in underwater environments. Whereas human vision is oblivious to components of light polarization, polarization parameters of light provide an important visual extension to intensity and color. A physical state of polarization can be visualized directly in human terms as a particular hue and saturation, and this paper utilizes such a scheme presenting image of ordinary scenes as never seen before by humans in the domain of Polarization Vision. Metaphorically, humans are 'color blind' with respect to the perception of polarization and even though this does not appear to inhibit human visual performance, we show how polarization vision is a sensory augmentation that can potentially enhance underwater vision for a diver.
Human-agent-robot teamwork (2012)

Teamwork has become a widely accepted metaphor for describing the nature of multi-robot and multi-agent cooperation. By virtue of teamwork models, team members attempt to manage general responsibilities and commitments to each other in a coherent fashion that both enhances performance and facilitates recovery when unanticipated problems arise. Whereas early research on teamwork focused mainly on interaction within groups of autonomous agents or robots, there is a growing interest in leveraging human participation effectively. Unlike autonomous systems designed primarily to take humans out of the loop, many important applications require people, agents, and robots to work together in close and relatively continuous interaction. For software agents and robots to participate in teamwork alongside people in carrying out complex real-world tasks, they must have some of the capabilities that enable natural and effective teamwork among groups of people. Just as important, developers of such systems need tools and methodologies to assure that such systems will work together reliably and safely, even when they have been designed independently.
RCWA-EIS method for interlayer grating coupling (2016)

The grating coupling efficiencies for interlayer connection (overlaid chips) were previously calculated using the new rigorous coupled-wave analysis equivalent-index-slab (RCWA-EIS) method. The chip-to-chip coupling efficiencies were determined for rectangular-groove (binary) gratings. In the present work, the search algorithms used in the RCWA-EIS method are optimized giving rise to improved definition of equivalent indices. Further, the versatility of the RCWA-EIS method is demonstrated by extending it to (nonbinary) parallelogramic gratings, sawtooth gratings, and volume gratings. The finite-difference time-domain method is used to verify the results. This demonstrates the flexibility of the RCWA-EIS method in analyzing arbitrary 1D gratings.
Effect of bath contamination on electroplated solder bumps (2016)

Today's solder bumping technologies commonly require electroplating multiple metallurgies. Chip manufacturers often process these multi-metal bumping wafers on the same equipment. Handling multiple metal baths on the same equipment inherently carries some risks of bath cross-contamination due to drag-out. Understanding the effect of bath cross-contamination can help chip manufacturers assess production risks in events of inadvertent and significant contamination, due to processing, equipment, or human errors. This paper summarizes the effect of cross-contamination on the on-wafer performance of electroplated solder bumps. Plating baths were deliberately contaminated by copper and nickel metals at levels of 0, 10, 100, 500 ppm. CuSnAg and NiSnAg bumps were plated in those contaminated baths. The bumps were then evaluated based on parameters such as metal content in contaminated films, bump height non-uniformity and coplanarity, bump morphology/defects, Ag% in solder bumps, shear strength, bump adhesion, and intermetallic compounds (IMC) formation. The results showed detrimental effect by Cu-contaminated Ni at levels above 100 ppm due to degradation of Ni crystal structure. In case of Ni-contaminated SnAg, there was essentially no effect, not even at 500 ppm, because Ni was not found incorporated into the SnAg films. For Cu-contaminated SnAg, there appeared to be some effect on shear strength at 100 ppm, and surface appearance at 500 ppm.
Vertically Aligned Platinum Copper Nanotubes as PEM Fuel Cell Cathode: Elaboration and Fuel Cell Test (2018)

Abstract This paper describes the elaboration via an electrochemistry route of a PEM carbon‐free cathode made of a periodic array of vertically aligned platinum copper nanotubes. Nanotubes synthesis is assisted with a porous alumina mold made on a silicon substrate to perform growth of copper nanowires. After optimization of an original confined galvanic displacement with H 2 PtCl 6 salt, PtCu nanotubes are embedded into porous alumina template and directly integrated onto a Nafion ® membrane. Therefore, our process does not need any step of purification or catalyst dispersion. The performances in fuel cell of these new electrodes are compared to conventional structures made of Tanaka Pt/C with the same electrocatalytic surface area. Significant improvement in the specific activity at 0.9 V and reduction in mass transport limitations are observed compared with standard Tanaka Pt/C catalyst in real operating conditions.
Nonlinear Interference Mitigation: Methods and Potential Gain (2017)

We explore the potential benefits of digital nonlinearity compensation (NLC) techniques in fully loaded coherent wavelength-division multiplexed (WDM) transmission systems. After providing an overview of the various classes of nonlinear interference noise (NLIN) and digital signal processing approaches for their mitigation, we consider the two practically most relevant digital NLC methods known today: back-propagation (BP) and equalization of nonlinear phase and polarization rotation noise (PPRN). We consider a wide range of system configurations including a variety of modulation formats from quadrature phase-shift keying (QPSK) to 256-ary quadrature amplitude modulation (QAM), single-carrier and digital subcarrier multiplexed (SCM) optical superchannels, as well as both point-to-point line systems and optically routed networks (ORNs). Using theoretical predictions from the time-domain model for NLIN, we show that the gain in peak signal-to-noise ratio in fully loaded WDM systems using single-channel and three-channel joint BP is typically limited to 0.5 and 1 dB. The additional gain provided by increasing the number of jointly back-propagated channels beyond three is limited to 0.1 dB per additional back-propagated channel. The remarkably slow growth of the BP gain with the bandwidth of the back-propagated signal is shown to apply also for systems in which the receiver employs PPRN removal. We additionally explore the potential benefits of SCM across a wide range of system configurations, including the impact of BP and PPRN removal on SCM systems. We show that while the BP gain is similar to single-carrier systems, PPRN removal can have a much stronger effect, particularly for higher order QAM systems, implying that SCM can be advantageous not only for constant modulus formats such as QPSK, but also for high spectral efficiency systems. In the context of ORNs, we find that SCM not only improves system tolerance to nonlinearities, but also induces significantly smaller performance variations in various ORN scenarios.
Design of an Interstitial Microwave Applicator for 3D Printing in the Body (2020)

This paper describes a method for 3D printing in the body using a coaxial applicator to heat a biopolymer that solidifies when heated. This method is proposed for creating conductive lines in the body for focusing electromagnetic fields on a very small (4 mm on a side) implantable medical device. A 2450 MHz sleeved slot coaxial applicator with a pointed, extended, hollow tip is designed to heat 400 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> of polymer from body temperature to its crosslinking temperature of 40 °C in 10 s.
An alternative way to initiate Notch1 signaling in non-small cell lung cancer. (2014)

Non-small cell lung cancer (NSCLC) cells activate Notch1 signaling to promote cell proliferation and facilitate their survival. It now emerges that endothelial Delta-like ligand 4 (Dll4) may mediate Notch1 activation and inhibit tumor cell growth.
Fully Automated Closed-Loop Insulin Delivery Versus Semiautomated Hybrid Control in Pediatric Patients With Type 1 Diabetes Using an Artificial Pancreas (2008)

Closed-loop glucose control using an external sensor and insulin pump provides a means to achieve near-normal glucose concentrations in youth with type 1 diabetes during the overnight period. The addition of small manual priming bolus doses of insulin, given 15 min before meals, improves postprandial glycemic excursions.
CRISPR/Cas12a collateral cleavage activity for an ultrasensitive assay of RNase H (2021)

We herein describe an ultrasensitive RNase H assay by utilizing CRISPR/Cas12a collateral cleavage activity. Based on this unique design principle, the RNase H activity was successfully determined down to 0.00024 U mL<sup>-1</sup>, which is quite superior to those of alternative approaches.
Abstract 2790: Localization of the binding site for Peloruside A and Laulimalide on beta-tubulin by physical and biological means (2012)

Abstract Peloruside A (Pel) and laulimalide (Laul) are microtubule-stabilizing natural products that were discovered recently compared to more established agents such as the taxanes and the epothilones. The activities of Pel and Laul are synergistic with taxanes or epothilones but not with each other, indicating separate binding sites and distinct mechanisms for Pel and Laul compared to taxanes and epothilones. Hence the location and nature of the Pel / Laul binding site is of interest. We have identified this site by a physical method (mass spec H-D footprinting) and a biological one: isolating Pel-resistant mutants of human ovarian carcinoma cells (A2780 (1A9)). Four Pel-resistant lines were obtained with single-base mutations in class I β-tubulin which resulted in the following substitutions: R306H, Y340S, N337D, and A296S in various combinations. The mutations localize to the peptides identified by the mass spec method, and center on a cleft in which modeling indicates that the Pel and Laul side chains dock. The site is accessible from the outside of the microtubule and does not overlap the Taxol site on β-tubulin. The Pel resistant lines are cross resistant to Laul, but not to any other microtubule stabilizing drug, and show no cross-sensitivity to microtubule destabilizing drugs. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 2790. doi:1538-7445.AM2012-2790
Effect of Nutritional Spray Regimes on Orange Juice Flavor Quality and Juice Liberibacter (CLas) DNA Detection (2012)

Huanglongbing (HLB) has been spreading statewide in Florida. Removal of infected trees is the most effective way to control spread of the disease. However, under the current decreasing production trend (annual production is down from 220 million boxes before the attempt at canker eradication and two severe hurricane seasons in 2004 and 2005 to currently less than 140 million boxes) it is difficult to remove more trees for any reason. Thus, many growers have set up their management strategy on two major practices: reducing psyllid populations with insecticides, and applying a nutritional spray program to alleviate HLB tree symptoms. As a result, more and more fruit for juice extraction will be HLB infected. Orange juice, processed from symptomatic HLB-infected fruit, has been associated with bitter taste and/or off-flavor. However, there is no single indicator that can be used to predict quality loss of juice due to HLB. Furthermore, it is unknown how nutritional sprays influence fruit and juice flavor. The objectives of this research are to determine how quantitative real-time PCR (qPCR), one of the most reliable HLB diagnostic methods, can be adapted to detect the HLB supposed pathogen DNA in juice, and then how nutritional spray regimes influence juice quality and qPCR results. ‘Hamlin’ and ‘Valencia’ orange trees with or without HLB infection were sprayed with three different nutritional formulations. The fruit were harvested and processed using a commercial juicer. The samples were analyzed for sugars, acids, limonoids, and volatiles, and evaluated by sensory panels for the aroma and taste, and qPCR for the pathogen bacterial population. The results showed that juice processed from symptomatic HLB fruit contained more of the bitter compounds, limonin and nomilin, and was perceived by the panel as bitter, astringent, grapefruit-like, sour, metallic, earthy, or simply “flat.” The pathogen population detected by qPCR was lowest in control (healthy) fruit juice and highest in HLB symptomatic fruit juice. Juice processed from HLB asymptomatic fruit had less off flavor and lower pathogen population than did juice from HLB symptomatic fruit. Fruit grown under the nutritional spray programs had similar off flavor problems in ‘Hamlin’ juice, but resulted in sweeter juice for ‘Valencia’. The nutritional treatments did not consistently result in less pathogen DNA for either variety, however.
ApoA-1 Milano and Regression of Atherosclerosis (2004)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Modeling of solubilization dynamics of manure organic matter and phosphorus as a function of pH control and enzyme supplementation (2016)

The potential use of commercial enzyme and pH control has been investigated for enhancing dairy manure fermentation and modeling dissolved organic matter and orthophosphate (PO4-P) dynamics of fermenters. Anaerobic lab-scale batch fermenters (initial total solids concentration (TSo) = 3.8 wt. %) were fed with separated dairy manure solids and operated under pH controls (5 and 9.5). The enzymesupplemented alkaline fermenters clearly outperformed the acidic fermenters in terms of chemical oxygen demand (COD) solubilization: ca. 50% vs. 20%, respectively. Soluble PO4-P in the acidic fermenters was comparably higher but constituted less than 20% of total phosphorus. Better soluble COD (>80%) and soluble PO4-P (>70%) yields were noted for the dilute fermenters (TSo = 0.6-0.8 wt. %). An existing model was retrofitted, calibrated and validated for simulating dynamics of soluble COD, volatile fatty acids, and soluble orthophosphate under various pH and enzyme conditions.