gebhart/patrepeval huggingface dataset:
192: Tubularized Urethral Replacement: What is the Maximum Distance for Normal Tissue Regeneration? (2004)

You have accessJournal of UrologyDiscussed Poster, Saturday, May 8, 2004, 1:00 - 5:00 pm1 Apr 2004192: Tubularized Urethral Replacement: What is the Maximum Distance for Normal Tissue Regeneration? Roger E. De Filippo, Hans G. Pohl, James J. Yoo, and Anthony Atala Roger E. De FilippoRoger E. De Filippo , Hans G. PohlHans G. Pohl , James J. YooJames J. Yoo , and Anthony AtalaAnthony Atala View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)37454-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "192: Tubularized Urethral Replacement: What is the Maximum Distance for Normal Tissue Regeneration?." The Journal of Urology, 171(4S), p. 51 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 171Issue 4SApril 2004Page: 51 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Roger E. De Filippo More articles by this author Hans G. Pohl More articles by this author James J. Yoo More articles by this author Anthony Atala More articles by this author Expand All Advertisement PDF downloadLoading ...
ChemInform Abstract: Zeolite Synthesis: Can It Be Designed? (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Follow‐Up (2012)

Follow-up of implantable cardiac devices is critical from the standpoint of patient safety, patient satisfaction, device optimization, the patient's physical and psychologic well-being, and often for chronic disease management. It is a requirement that arrangements be made for chronic surveillance at the time of device implantation. Routine approaches for frequency of follow-up, remote-monitoring or trans-telephonic surveillance, periodic in-clinic evaluation should all be established. Algorithms for in-clinic interrogation and programming as well as guidelines for troubleshooting should be developed and followed as part of device clinic follow-up. Patient education is critical and although it may be considered largely an activity to be completed at the time of device implantation, ongoing education is often required. Patient management in the presence of a device advisory or recall must be understood and is often facilitated by a standard approach. Psychologic issues that arise related to implantable devices should also be anticipated in the follow-up period and qualified personnel be available to counsel and educate patients on these issues.
ChemInform Abstract: THIABENZENES PART 1, A REINVESTIGATION OF ′STABLE THIABENZENES′ (1974)

Die Deprotonierung der Thioxanthyliumsalze (I) ergibt die Thioxanthene (II), die aus der raschen Umlagerung der zunächst gebildeten Thiaanthracene hervorgehen, wie NMR-spektroskopische Untersuchungen zeigen.
Inter-reader variation in lung segmentation of functional lung MRI quantification (2019)

<b>Background:</b> Functional lung imaging with MRI allows evaluation of ventilation and perfusion deficits in lung disease. To quantify deficits, segmentation of lung tissue is required, which is subjective and time-consuming. Deep learning (DL) algorithms could accelerate this process with high precision. <b>Aim:</b> We assessed the variation in relative impaired ventilation and perfusion resulting from segmentations from different readers. <b>Methods:</b> This study included 29 MRI scans from 17 children with cystic fibrosis and 9 healthy. Pulmonary tissue was segmented on base images. A matrix pencil algorithm computed perfusion- and ventilation-weighted maps of the lung and calculated the relative fractional ventilation (R<sub>FV</sub>) and perfusion (R<sub>Q</sub>) impairment. The R<sub>FV</sub> and R<sub>Q</sub> resulting from the segmentations of two experienced human readers (A &amp; B) and a recurrent neural network (DL) were compared. Reader A repeated segmentation after 24 hours to investigate intra-reader variability. Agreement between readers was assessed with paired t-test and intra-class correlation coefficient (ICC). <b>Results:</b> There was very good agreement between all readers (ICC: 0.98; 0.92 - 0.99). There was a significant difference in R<sub>FV</sub> from reader A (mean=26.8; SD=6.4) to B (28.2; 6.1; p&lt;0.001) and DL (28.0; 6.3; p&lt;0.001). No significant differences in repeated segmentation from reader A (difference: -0.03; p=0.62) were found. The differences for R<sub>Q</sub> were comparable to R<sub>FV</sub>. <b>Conclusion:</b> We found small but statistically significant differences in outcomes between observers. The inter-reader variability of R<sub>FV</sub> and R<sub>Q</sub> between human and machine was similar to the variability between human readers. DL may be a promising alternative to human segmentation.
Multiplexed In Situ Spatial Protein Profiling in the Pursuit of Precision Immuno-Oncology for Patients with Breast Cancer (2022)

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of many solid tumors. In breast cancer (BC), immunotherapy is currently approved in combination with chemotherapy, albeit only in triple-negative breast cancer. Unfortunately, most patients only derive limited benefit from ICIs, progressing either upfront or after an initial response. Therapeutics must engage with a heterogeneous network of complex stromal-cancer interactions that can fail at imposing cancer immune control in multiple domains, such as in the genomic, epigenomic, transcriptomic, proteomic, and metabolomic domains. To overcome these types of heterogeneous resistance phenotypes, several combinatorial strategies are underway. Still, they can be predicted to be effective only in the subgroups of patients in which those specific resistance mechanisms are effectively in place. As single biomarker predictive performances are necessarily suboptimal at capturing the complexity of this articulate network, precision immune-oncology calls for multi-omics tumor microenvironment profiling in order to identify unique predictive patterns and to proactively tailor combinatorial treatments. Multiplexed single-cell spatially resolved tissue analysis, through precise epitope colocalization, allows one to infer cellular functional states in view of their spatial organization. In this review, we discuss-through the lens of the cancer-immunity cycle-selected, established, and emerging markers that may be evaluated in multiplexed spatial protein panels to help identify prognostic and predictive patterns in BC.
Microscopy investigations. Techniques, results, limitations. (2000)

This paper critically reviews current microscopy techniques that are used to image resin-dentin interfaces and more in particular to investigate the process of hybridization and resin-tag formation. A short description of the four most commonly used microscopy techniques with their necessary specimen-preparation methodology is provided along with a discussion of their possibilities, limitations and potential artifact formation. With this critical appraisal on microscopy techniques available to study adhesive interfaces, it is hoped to encourage the use of high-resolution analytical tools to further elucidate the mechanisms of bonding at the ultra-structural level. Besides ultra-morphologic characterization, more research should be devoted to study the chemical and physical properties of resin-dentin bonds. The final objective of such fundamental research should be to establish a more durable and reliable adhesive restorative technique.
Design of New Positive-Tone Photoresists Based on the Acid-Catalyzed Hydrolysis of Phenylmethanediol Diesters (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDesign of New Positive-Tone Photoresists Based on the Acid-Catalyzed Hydrolysis of Phenylmethanediol DiestersS. Ming Lee and Jean M. J. FrechetCite this: Chem. Mater. 1994, 6, 10, 1830–1837Publication Date (Print):October 1, 1994Publication History Published online1 May 2002Published inissue 1 October 1994https://pubs.acs.org/doi/10.1021/cm00046a042https://doi.org/10.1021/cm00046a042research-articleACS PublicationsRequest reuse permissionsArticle Views114Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Scintillation and Dosimetric Properties of Ce:CsCl Transparent Ceramics (2018)

Ce:CsCl transparent ceramics doped with different concentrations of Ce (0.01, 0.1, and 1 mol.%) were synthesized by spark plasma sintering, and their optical, scintillation and dosimetric properties were investigated. Regarding the scintillation properties, X-ray-induced scintillation spectra of the samples consisted of three emission peaks at around 280, 380, and 400 nm, which were due to the Auger-free luminescence and 5d4f ( 2 F 5/2 and 2 F 7/2 ) transitions of Ce 3+ , respectively. In addition, the samples showed thermally stimulated luminescence (TSL) and optically stimulated luminescence (OSL) with emission peaks centering at around 400 and 480 nm, in which the origins were attributed to the 5d-4f transitions of Ce 3+ and the host, respectively. In particular, the TSL was sensitive to X-rays, and the TSL signals as low as 0.1 mGy were measurable, while a linear response was confirmed up to 100 mGy.
Insights After 40 Years of the Fontan Operation (2010)

Fontan's visionary operation and its modifications over the ensuing decades have re-established nonturbulent flow and substantially reduced cyanosis for patients with severe hypoplasia of one ventricle. However, a long list of largely unexpected sequelae has emerged over the last 40 years. Although it is not difficult to understand how care providers could become discouraged, a number of myths have arisen, which we will attempt to dispel with real-world counterexamples as well as with lessons learned from other disciplines: evolutionary, developmental, and computational biology. We argue that distinctive biochemical abnormalities pointing to dysfunction in multiple organs, including the largest organ system in the body, the endothelium, occur long before grossly observable changes in cardiac imaging can be recognized. With a rational redesign of both our surveillance scheme and our wellness strategies, we hope that Fontan survivors and their families, as well as physicians, nurses, and therapists, will see why Fontan's principle remains just as vibrant today as it was in 1971.
High-rate distributed multi-source cooperation using complex field coding (2009)

A multisource cooperative protocol is developed capable of achieving diversity order up to the number of cooperating users at a high throughput. In this design each source jointly encodes its own new information symbol with the information symbols received from other sources at past instants. Joint encoding is done using linear complex-field coefficients. Throughput analysis shows gains with respect to existing multi-source protocols and approaches the throughput of non-cooperative schemes. Diversity analysis shows that full spatial diversity is achievable. Simulations confirm the analytically established assessments.
Measurement of the absolute rate of 1,2-hydrogen migration in benzylchlorocarbene (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMeasurement of the absolute rate of 1,2-hydrogen migration in benzylchlorocarbeneJames E. Jackson, N. Soundararajan, Walter White, Michael T. H. Liu, Roland Bonneau, and Matthew S. PlatzCite this: J. Am. Chem. Soc. 1989, 111, 17, 6874–6875Publication Date (Print):August 1, 1989Publication History Published online1 May 2002Published inissue 1 August 1989https://pubs.acs.org/doi/10.1021/ja00199a076https://doi.org/10.1021/ja00199a076research-articleACS PublicationsRequest reuse permissionsArticle Views102Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Tumor Evolution Inferred by Patterns of microRNA Expression through the Course of Disease, Therapy, and Recurrence in Breast Cancer (2016)

Serial tumor sampling combined with analysis of temporal expression patterns enabled to pinpoint significant signatures characterizing breast cancer progression, associated with response to therapy and with risk of recurrence. Clin Cancer Res; 22(14); 3651-62. ©2016 AACR.
Cellular senescence impairs the reversibility of pulmonary arterial hypertension (2020)

Pulmonary arterial hypertension (PAH) in congenital cardiac shunts can be reversed by hemodynamic unloading (HU) through shunt closure. However, this reversibility potential is lost beyond a certain point in time. The reason why PAH becomes irreversible is unknown. In this study, we used MCT+shunt-induced PAH in rats to identify a dichotomous reversibility response to HU, similar to the human situation. We compared vascular profiles of reversible and irreversible PAH using RNA sequencing. Cumulatively, we report that loss of reversibility is associated with a switch from a proliferative to a senescent vascular phenotype and confirmed markers of senescence in human PAH-CHD tissue. In vitro, we showed that human pulmonary endothelial cells of patients with PAH are more vulnerable to senescence than controls in response to shear stress and confirmed that the senolytic ABT263 induces apoptosis in senescent, but not in normal, endothelial cells. To support the concept that vascular cell senescence is causal to the irreversible nature of end-stage PAH, we targeted senescence using ABT263 and induced reversal of the hemodynamic and structural changes associated with severe PAH refractory to HU. The factors that drive the transition from a reversible to irreversible pulmonary vascular phenotype could also explain the irreversible nature of other PAH etiologies and provide new leads for pharmacological reversal of end-stage PAH.
Protocol-based business process modeling and enactment (2004)

Business processes are conventionally modeled as monolithic flows that capture the desired business logic. However, developing process flows is challenging. Because a flow specifies what its participants should do, it restricts the autonomy of its participants, thus limiting their ability to exploit opportunities or accommodate exceptions according to their business preferences. We take a dual perspective wherein business processes are modeled as compositions of (instantiated) business protocols. Each business protocol specifies interactions among its partners; each protocol serves a unique business purpose, e.g., processing a payment or shipping an item. Thus, modularizing a monolithic business process via business protocols allows clear separation of concerns for modeling and enacting the process. We develop an approach in which protocols are compiled into local skeletal flows for each participant that can be fleshed out with local business logic as needed. Such flows are naturally distributed but can be enacted using commercial business flow engines. Thus, our protocol-based approach combines the benefit of improved modeling with simplified implementations.
The Correlation of Fatigue Crack Growth Rates in Rubber Subjected to Multiaxial Loading Using Continuum Mechanical Parameters (2007)

Abstract Although both the crack nucleation and growth stages of the fatigue failure process in rubber are manifestations of the same characteristic material behavior, the nucleation stage deserves special attention. In this case, continuum mechanical parameters may be used to characterize the driving forces of small cracks, without reference to the geometry of the test piece. The ability to estimate crack driving forces from continuum mechanical parameters during the growth process of small cracks has been investigated by correlating three different parameters (maximum principal strain, strain energy density, and cracking energy density) to rates of crack growth observed photographically during fatigue tests on initially uncracked specimens. Significant scatter in crack growth rates was observed resulting from high crack density and crack interactions. These results are also compared to crack growth measurements made on a pure shear (planar tension) test piece. The difference between continuum parameters that refer to a specific material plane, and those that do not is emphasized. Generally, the maximum principal strain and cracking energy density parameters provided similar levels of correlation. The strain energy density parameter consistently gave the poorest correlation. An advantage of the cracking energy density is that it considers the experiences of specific planes embedded in the material ( i.e. it is a plane-specific parameter).
Block copolymers by transformation of “living” carbocationic into “living” radical polymerization. II. ABA‐type block copolymers comprising rubbery polyisobutene middle segment (1997)

A general method for the transformation of “living” carbocationic into “living” radical polymerization, without any modification of chain ends, is reported for the preparation of ABA block copolymers. For example, α,ω-difunctional polyisobutene, capped with several units of styrene, Cl-St-PIB-St-Cl, prepared cationically (Mn = 7800, Mw/Mn = 1.31) was used as an efficient difunctional macroinitiator for homogeneous “living” atom transfer radical polymerization to prepare triblock copolymers with styrene, PSt-PIB-PSt (Mn = 28,800, Mw/Mn = 1.14), methyl acrylate, PMA-PIB-PMA (Mn = 31,810, Mw/Mn = 1.42), isobornyl acrylate, PIBA-PIB-PIBA (Mn = 33,500, Mw/Mn = 1.21), and methyl methacrylate, PMMA-PIB-PMMA (Mn = 33,500, Mw/Mn = 1.47). © 1997 John Wiley & Sons, Inc. J Polym Sci A: Polym Chem 35: 3595–3601, 1997
ChemInform Abstract: One‐Pot Synthesis of α,γ‐Disubstituted Tetronic Acids from α‐Hydroxyallyl Esters: A Novel “Tandem‐Wittig‐Claisen” Reaction. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Calculating BTDF from window surface roughness (2013)

The Rayleigh Rice vector perturbation theory has been successfully used for several decades to relate the surface power spectrum of optically smooth reflectors to the angular resolved scatter resulting from light sources of known wavelength, incident angle and polarization. A similar relationship should be available for the situation of a beam transmitting from a region of index greater than 1.0 into a region of unit index through an optically smooth surface. This paper presents such a relationship and compares the result to measured scatter data at two light wavelengths.
ChemInform Abstract: De Novo Design of Proteins. Template‐Assembled Synthetic Proteins ( TASP) (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Obsessive-compulsive disorder and comorbidity (2006)

Comorbidity of Obsessive Compulsive Disorder Obsessive-Compulsive Disorder and Major Depression: Associated and Different Obsessive-Compulsive Disorder: Comorbidity with Obsessive-Compulsive Spectrum Disorders Schizo-Obsessive Disorder Obsessive Compulsive Disorder and Attention Deficit Disorder: A Challenging Comorbidity Autism Spectrum Disorders, Autistic Traits and Personality Disorders in Obsessive Compulsive Disorder Neurological Disorders of the Basal Ganglia and Obsessive Compulsive Disorder Antipsychotics In OCD State of the Art and Future Directions in the Pathophysiology of Obsessive-Compulsive Disorder Index.
Neural Circuit Dynamics of Brain States (2019)

The brain, like other living systems, tolerates light, which can be delivered flexibly over a range of wavelengths and irradiance values. The fact that most cells do not respond to light provides an enormous signal-to-noise advantage—if any light sensitivity can be conferred. Our efforts on using light to illuminate brain structure and function have taken us from the basic science investigation of microbial protein crystal structures, to optical probing of brain structure and function using hydrogel-tissue chemistry and optogenetics.
Submilliamp long wavelength vertical cavity lasers (1996)

The authors demonstrate a low threshold laterally oxidised long wavelength (1.55 µm) vertical cavity laser. The devices exhibit the first submilliamp threshold current (0.8 mA) as well as the highest reported operating temperatures (64°C CW and 95°C pulsed) of any long wavelength vertical cavity laser.
Electronic Identities Need Private Credentials (2012)

For transactions on the Internet, user authentication typically involves usernames and passwords. When creating an account, users often must provide additional personal information. Usually, this is a list of self-claimed attributes such as name, address, or birth date. Only a few attributes such as email address and credit card information have some mechanism to authenticate them. Solutions such as the Security Assertion Markup Language, OpenID, or X.509 certificates let users authenticate and transfer attributes, certified by an issuer, to a relying party in a more trusted way. However, these technologies still have considerable security and privacy concerns. Private credentials are a superior solution. With them, issuers don't have to be involved during authentication. Also, users disclose only those attributes required by the relying parties and can do so without being easily tracked across their transactions.