gebhart/patrepeval huggingface dataset:
Correlation between the Anti‐Virus‐Induced Cytopathic Effect Activity of Interferon‐α Subtypes and Induction of MxA Protein In Vitro (2006)

There are several interferon-alpha (IFN-alpha) subtypes. Mechanism of disparity in biological effects among members of IFN-alpha subtypes remains unexplained. Biological activity of IFN-alpha is mediated in part by induction of intracellular antiviral proteins. We studied whether differences in biologic effects of IFN-alpha subtypes may rely on their antiviral protein inducing effect. Intracellular induction of MxA protein and anti-virus-induced cytopathic effect (CPE) activity of 11 IFN-alpha subtypes in human amnion WISH cells have been studied. MxA protein quantitation in cell lysates was performed by immunochemiluminescence assay and anti-virus-induced CPE activity was assessed by protection against vesicular stomatitis virus (VSV)-induced CPE. Range of MxA values was high when cells were treated with 10 and 100 IU/ml of each IFN-alpha subtype. Levels of MxA correlated with anti-VSV-induced CPE obtained with 10 IU/ml IFN-alpha subtype. Together our data show a disparity in MxA-inducing activity of IFN-alpha subtypes and suggest that differences in anti-VSV-induced CPE of IFN-alpha subtypes in WISH cells can be related to their different ability to induce MxA.
Deactivation of π-Complexation Adsorbents by Hydrogen and Rejuvenation by Oxidation (2001)

The π-complexation sorbents are the best sorbents for bulk olefin/paraffin separation and purification of normal α-olefins. Hydrogen produced during cracking operations would remain in small or trace amounts in the process streams. The effect of hydrogen exposure on Ag+-exchanged Y zeolite (AgY) and monolayer-dispersed AgNO3/SiO2 (π-complexation sorbents) on olefin adsorption was studied by using accelerated tests. Hydrogen exposure could severely deactivate the π-complexation sorbents for adsorption of ethylene, 1,3-butadiene, and 1-butene. XPS analysis indicated that the Ag+ ion responsible for π-complexation was partially reduced, hence, the deactivation. It was found that the deactivated sorbents could be rejuvenated by mild oxidation. The reoxidation of the H2-exposed AgY samples were carried out under different oxidation conditions to locate the optimum conditions. The treatment of the H2-exposed samples to 0.13 atm of O2 in He at 350 °C for 0.5 h was the best reoxidation condition achieved in this study.
Constant pace skimming and temporal sub-sampling of video using motion activity (2002)

We describe a "constant pace" framework for video summarization via fast playback or temporal sub-sampling. The pace of the summary serves as a parameter that enables production of a video summary of any desired length. Earlier, we showed that the intensity of motion activity (or pace) of a video sequence is a good indication of its "summarizability". Here we build on this notion by adapting the playback frame-rate or the temporal subsampling rate to the pace. Either the less active parts of the sequence are played back at a faster frame rate or the less active parts of the sequence are sub-sampled more heavily than are the more active parts, so as to produce a summary with constant pace. The basic idea is to skip over the less interesting parts of the video. Our technique is computationally simple and gives satisfactory results with surveillance and entertainment video.
Supplementary Table 4 from Somatic <i>ERCC2</i> Mutations Correlate with Cisplatin Sensitivity in Muscle-Invasive Urothelial Carcinoma (2023)

&lt;p&gt;Significantly altered genes in clinical subsets. MutSigCV ranked lists for significantly mutated genes in the non-responders only (n = 25), the responders only (n = 25), and the ERCC2WT responders only (n = 16).&lt;/p&gt;
Semantically annotated hypermedia services (2005)

Hypermedia systems' researchers investigate the various approaches in the way documents and resources are linked, navigated and stored in a distributed environment. Unfortunately, those systems fail to provide effortlessly usable discrete services, since it is difficult both to discover and to invoke any of them. This paper proposes the usage of emerging technologies that try to augment the Web resources with semantics in order to provide Hypermedia services that can be easily discovered, and integrated by potential third party developers. In this context, we analyze the benefits for the Hypermedia community upon the adoption of Semantic Web technologies for the description of Hypermedia services, and we implement an initial corresponding ontology.
A 28-GHz Switched-Filter Phase Shifter with Fine Phase-Tuning Capability Using Back-Gate Biasing in 22-nm FD-SOI CMOS (2021)

This paper introduces a phase shifter based on switched filters for mm-wave 5G MIMO transmitters. It is realized in 22 nm FD-SOI CMOS and exploits the use of back-gate biasing. The new approach features strong tolerance to process, voltage and temperature (PVT) variations and thus can maintain low phase error with fine phase tuning capability supporting a large bandwidth. Measurement results show that the 4-bit phase shifter achieves 3.5° rms phase error at 28 GHz. The proposed phase shifter can maintain <5° of the worst-case rms phase error when operating across 24 to 29.5 GHz resulting in 20.56% fractional bandwidth which is the largest among the published switched-filter phase shifters to date.
C‐O Bond Cleavage of Diethyl Ether and Tetrahydrofurane by [(dpp‐BIAN)AlI(Et2O)] [dpp‐BIAN = 1,2‐bis[(2,6‐di‐iso‐propylphenyl)‐imino]acenaphthene] (2007)

Abstract At elevated temperatures, the aluminum complex [(dpp‐BIAN)AlI(Et 2 O)] ( 1 ) splits the C‐O bonds of diethyl ether and tetrahydrofurane yielding the dimeric alkoxides [(dpp‐BIAN)AlOEt] 2 ( 2 ) and [(dpp‐BIAN)AlO(CH 2 ) 4 I] 2 ( 3 ), respectively. Already at ambient temperatures, a cleavage of the C‐O bond of THF is to observe in the reaction of 1 with CpNa in THF as confirmed by the formation of [(dpp‐BIAN)AlO(CH 2 ) 4 C 5 H 5 ] 2 ( 4a ) and [(dpp‐BIAN)Al{O(CH 2 ) 4 C 5 H 5 }(THF)] ( 4b ) in a molar ratio of 1:2. The reaction of 1 with t ‐BuOK affords the monomeric alkoxide [(dpp‐BIAN)AlO‐ t ‐Bu(Et 2 O)] ( 5 ). Compounds 2 , 3 , and 4a/b were characterized by elemental analyses and IR spectra. Additionally, the structures of 2 and 3 were determined by single crystal X‐ray diffraction.
Dewetting Properties of Polystyrene Homopolymer Thin Films on Grafted Polystyrene Brush Surfaces (2000)

We have found that the critical molecular weight for auto dewetting of a homopolymer on a polymer brush of the same chemical composition is approximately N H = 0.5 N B , in good agreement with the mean field theory prediction. The measured velocity on the brush surface is at least an order of magnitude faster than that of the polystyrene (PS) on a homopolymer interface, with a greatly decreased dependence on the PS molecular weight. This suggests slippage as a possible mechanism for the dewetting dynamics.
On the High-Snr Receiver Operating Characteristic of Glrt for The Conditional Signal Model (2018)

This paper studies the performance of the generalized likelihood ratio test (GLRT) for the conditional signal model. By conditional signal model, we mean that under both hypotheses, the observations are a linear superposition of unknown deterministic signals corrupted by additive noise, with a mixing matrix depending on an unknown deterministic parameter vector. The contribution of this work is the derivation of closed form expressions for the probabilities of false alarm and of detection of the GLRT at high signal-to-noise ratio, allowing the receiver operating characteristic of the GLRT to be computed analytically. The most general case is tackled, i.e., when the number of unknown signals and the number of unknown deterministic parameters of the mixing matrix are allowed to be different under the two hypotheses.
Active spectro-polarimetric imaging: signature modeling, imaging demonstrator and target detection (2008)

We report on the synthesis of our work on the analysis of active spectro-polarimetric imaging concept of real-world scenes. These synthesis extend from the investigation of depolarization mechanisms up to image analysis and processing. We show in particular that depolarization effects are wavelength dependent and strongly correlated with light absorption of materials. Multi-wavelength images of degree of polarization are recorded and analyzed, evidencing that the polarimetric image must be interpreted in conjunction with its counterpart intensity image in order to extract, the most relevant information from the scene. For real field operation, the noise characteristics of polarimetric images are also investigated under coherent laser illumination. The potential increase of target detection performance brought by properly processing the active polarimetric image is illustrated on a very low contrast scene.
Permanent Magnet Vernier Machines: A Review (2018)

Permanent-magnet Vernier machines (PMVMs) gained a lot of interest over the past couple of decades. This is mainly due to their high torque density enabled by magnetic gearing effect. This paper will provide a thorough review of recent advances in PMVMs. This review will cover principle of operation and nature of magnetic gearing in PMVMs, and better understanding of novel PMVMs topologies using different winding configuration as well as different modulation poles and rotor structures. Detailed discussions on choice of gear ratio/slot-pole combinations, design optimization and role of advanced materials in PMVMs will be presented. This will provide an update on the current state of the art as well as future areas of research. Furthermore, design issues, fault tolerance as well as cost reduction will be discussed highlighting the gap between the current state of the art and what is needed in practical applications.
The generation of psychoacoustic combination tones in relation to two-tone suppression effects in a computational model (1997)

The amplitude of the psychoacoustic distortion product 2 f1−f2 elicited by primaries f1 and f2 depends on the method of measurement. The cancellation-tone procedure gives consistently higher estimates of the distortion product than nonsimultaneous procedures. It was suggested that the difference could be attributed to suppression effects by the lower primary f1 [Smoorenburg, J. Acoust. Soc. Am. 52, 615–632 (1972)]. Simulations carried out with a computational model of the auditory periphery including a single, but distributed, compressive nonlinearity confirm the hypothesis; the amount of suppression produced at 2 f1−f2 by f1 equals the difference between simultaneous and nonsimultaneous methods of measuring the amplitude of the distortion product. This is in agreement with psychoacoustical data [Shannon and Houtgast, J. Acoust. Soc. Am. 68, 825–829 (1980)]. The model also reveals the importance of suppression effects by f1 to bring the phase of the traveling wave associated with the cancellation tone 2 f1−f2 in exact opposition with that of the distortion product 2 f1−f2 generated by the primaries. There is also evidence of suppression effects by the higher primary f2 when L2≫L1. In the model, cancellation occurs over a substantial portion of the basilar membrane near the characteristic place for 2 f1−f2.
Coordinate-Based Seismic Interpolation in Irregular Land Survey: A Deep Internal Learning Approach (2022)

Physical and budget constraints often result in irregular sampling, which complicates accurate subsurface imaging. Pre-processing approaches, such as missing trace or shot interpolation, are typically employed to enhance seismic data in such cases. Recently, deep learning has been used to address the trace interpolation problem at the expense of large amounts of training data to adequately represent typical seismic events. Nonetheless, most research in this area has focused on trace reconstruction, with little attention having been devoted to shot interpolation. Furthermore, existing methods assume regularly spaced receivers/sources failing in approximating seismic data from real (irregular) surveys. This work presents a novel shot gather interpolation approach which uses a continuous coordinate-based representation of the acquired seismic wavefield parameterized by a neural network. The proposed unsupervised approach, which we call coordinate-based seismic interpolation(CoBSI), enables the prediction of specific seismic characteristics in irregular land surveys without using external data during neural network training. Experimental results on real and synthetic 3D data validate the ability of the proposed method to estimate continuous smooth seismic events in the time-space and frequency-wavenumber domains, improving sparsity or low-rank-based interpolation methods.
Remote Training for Medical Staff in Low-Resource Environments Using Augmented Reality (2022)

This work aims to leverage medical augmented reality (AR) technology to counter the shortage of medical experts in low-resource environments. We present a complete and cross-platform proof-of-concept AR system that enables remote users to teach and train medical procedures without expensive medical equipment or external sensors. By seeing the 3D viewpoint and head movements of the teacher, the student can follow the teacher's actions on the real patient. Alternatively, it is possible to stream the 3D view of the patient from the student to the teacher, allowing the teacher to guide the student during the remote session. A pilot study of our system shows that it is easy to transfer detailed instructions through this remote teaching system and that the interface is easily accessible and intuitive for users. We provide a performant pipeline that synchronizes, compresses, and streams sensor data through parallel efficiency.
Why Was My Paper Rejected without Review? (2020)

Environmental Science &amp; Technology has a proud history of publishing outstanding science in environmental science research. The journal takes great pride in excellence in the review process, including the quality and constructive tone of peer review feedback. These high standards and expectations of the publication are defined and maintained by a diverse team of global scientific experts. This quality review process is fundamental to ES&amp;T’s ability to publish the most important and impactful research in our field, and the journal would like to express its gratitude to the dedicated scientific researchers who donate their time and expertise in delivering this excellence in review.
A new sensitive direct radioimmunoassay for human plasma renin and its clinical application. (1984)

We developed new sensitive direct radioimmunoassay for human plasma renin. Renin was purified from Haas' preparation utilizing a pepstatin-C6-Sepharose affinity chromatography. Antiserum, prepared by immunizing rabbits with the purified renin, was used for the direct radioimmunoassay at a final dilution of 1:30,000. The antibody was specific for human renal and plasma renin, but did not cross-react with cathepsin D, trypsin, or renins of mouse, dog, and rat. Radioimmunoassay was performed by the double antibody technique using the delayed tracer addition method. In this method, a standard curve was obtained over a range from 0.2 to 8.0 ng/ml. The values from our assay correlated well with total renin activity measured as the generation rate of angiotensin I after trypsin activation (r = 0.78, p less than 0.01), but correlated weakly with active renin activity. This finding disclosed that both active and inactive renin were detected by this method. In normal participants, plasma renin concentration determined by direct radioimmunoassay was increased by standing and furosemide injection. The plasma renin concentration determined by direct radioimmunoassay of patients with essential hypertension (0.7 to 1.7 ng/ml) was not significantly different from values in normal controls (0.8 to 1.9 ng/ml). The values were higher in patients with renovascular hypertension (1.6 to 2.7 ng/ml), malignant hypertension (2.8 to 3.4 ng/ml) and Bartter's syndrome (1.8 to 2.5 ng/ml), but lower in patients with primary aldosteronism (0.4 to 0.8 ng/ml) than in normal controls. This newly developed radioimmunoassay for human renin was sensitive enough to estimate the levels of renin in plasma of patients with low renin hypertension. It provides a new tool for the understanding of the renin-angiotensin system under various clinical conditions.
Effect of partition coefficient, permeability surface product, and radioisotope on the signal-to-noise ratio in PET functional brain mapping: a computer simulation (1999)

In this work we use a computer simulation to estimate the magnitude of improvement in the signal-to-noise ratio of PET functional brain mapping studies as a function of partition coefficient and permeability surface product for O-14, F-17, and O-15 labeled flow tracers. A model for signal-to-noise ratio is derived from the Kety model for inert diffusible blood flow tracers. The results of the simulation suggest that moderate increases in partition coefficient and permeability surface product compared with water would lead to an increase in signal-to-noise ratio of a factor of about 3.
Nonlinearity of photonic quantum memristors in high-frequency regime (2022)

Over the last decades, the combination of quantum computing and machine learning has opened many possibilities, for example enhancing machine learning algorithms through quantum platforms. However, one of the current challenges consists in combining the linear unitary evolution of closed quantum systems with the nonlinearity required by neural networks, which are currently the most widely used and versatile machine learning algorithms. This issue can now be addressed by a novel photonic tool, the quantum memristor,1 which displays a nonlinear behavior, while preserving quantum coherence, through a weak controlled interaction of its input state with the environment. Here, we show how its operation can be extended to deal with higher frequency modulations of the input and, possibly, with a simplification in its scheme. This method can prove useful for the future implementation of memristor-based quantum neural networks.
Capturing magnetic bead-based arrays using perpendicular magnetic anisotropy (2019)

Designing and implementing means of locally trapping magnetic beads and understanding the factors underlying the bead capture force are important steps toward advancing the capture-release process of magnetic particles for biological applications. In particular, capturing magnetically labeled cells using magnetic microstructures with perpendicular magnetic anisotropy (PMA) will enable an approach to cell manipulation for emerging lab-on-a-chip devices. Here, a Co (0.2 nm)/Ni (0.4 nm) multilayered structure was designed to exhibit strong PMA and large saturation magnetization (<i>M</i> <sub><i>s</i></sub> ). Finite element simulations were performed to assess the dependence of the capture force on the value of <i>M</i> <sub><i>s</i></sub> . The simulated force profile indicated the largest force at the perimeter of the disks. Arrays of Co/Ni disk structures of (4-7) <i>μ</i>m diameter were fabricated and tested in a microchannel with suspended fluorescent magnetic beads. The magnetic beads were captured and localized to the edge of the disks as predicted by the simulations. This approach has been demonstrated to enable uniform assembly of magnetic beads without external fields and may provide a pathway toward precise cell manipulation methods.
P-075 (2012)

Malek, Angela; Stickler, David; Bowser, Robert; Heiman-Patterson, Terry; Lacomis, David; Rana, Sandeep; Talbott, Evelyn; Lackland, Daniel Author Information
Associations of Physical Activity and Television Viewing Time with Retinal Vascular Caliber in a Multiethnic Asian Population (2011)

PURPOSE. The aim of this study was to examine the relationship of physical activity and television (TV) viewing time with retinal vascular caliber in a multiethnic Asian population. METHODS. Chinese, Indian, and Malay participants (n = 3866) were examined cross-sectionally in the Singapore Prospective Study Program (2004-2007). Leisure-time physical activity and TV viewing time were assessed by the use of an interviewer-administered questionnaire. Retinal arteriolar and venular calibers were measured from digital retinal photographs. RESULTS. After adjusting for demographic, behavioral, and medical factors, those in the lowest quartile of leisure-time physical activity had a wider venular caliber (by 1.51 μm; 95% confidence interval [CI], 0.01-2.92) compared with those in the highest quartile. Using sex- and ethnicity-specific quartiles, stronger associations were noted in males (2.23 μm; 95% CI, 0.10-4.38) and Chinese (2.52 μm; 95% CI, 0.44-4.59) participants. Females who watched >2 hours of TV per day had a narrow arteriolar caliber (by 1.28 μm; 95% CI, -2.56--0.03), compared with the arteriolar caliber of those who watched less TV. CONCLUSIONS. Lower physical activity and higher TV viewing time (in females) were adversely associated with retinal microvascular caliber among Asian adults. Additional cross-sectional and longitudinal studies are needed to further clarify the potential mediating role of the microvasculature in the relationship between these behavioral risk factors and poor cardiometabolic health outcomes.
Supplementary Figure 1 from Systematic Interrogation of 3q26 Identifies <i>TLOC1</i> and <i>SKIL</i> as Cancer Drivers (2023)

&lt;p&gt;Supplementary Figure 1 - PDF file 25K, Correlation between TLOC1 suppression and cell proliferation&lt;/p&gt;
Correlation of supermode noise of harmonically modelocked lasers (2006)

Two types of supermode noise, uncorrelated and correlated, are demonstrated for two different types of harmonically modelocked lasers. The correlated supermode noise is originated from the excitation of multiple correlated optical supermodes.
Molecular Pathways: Vasculogenic Mimicry in Tumor Cells: Diagnostic and Therapeutic Implications (2012)

Tumor cell vasculogenic mimicry (VM) describes the functional plasticity of aggressive cancer cells forming de novo vascular networks, thereby providing a perfusion pathway for rapidly growing tumors, transporting fluid from leaky vessels, and/or connecting with endothelial-lined vasculature. The underlying induction of VM seems to be related to hypoxia, which may also promote the plastic, transendothelial phenotype of tumor cells capable of VM. Since its introduction in 1999 as a novel paradigm for melanoma tumor perfusion, many studies have contributed new insights into the underlying molecular pathways supporting VM in a variety of tumors, including melanoma, glioblastoma, carcinomas, and sarcomas. In particular, critical VM-modulating genes are associated with vascular (VE-cadherin, EphA2, VEGF receptor 1), embryonic and/or stem cell (Nodal, Notch4), and hypoxia-related (hypoxia-inducible factor, Twist1) signaling pathways. Each of these pathways warrants serious scrutiny as potential therapeutic, vascular targets, and diagnostic indicators of plasticity, drug resistance, and the aggressive metastatic phenotype.