gebhart/patrepeval huggingface dataset:
Design of reconfigurable heterogeneous modular architecture for service robots (2008)

This paper presents the design and implementation of a reconfigurable heterogeneous modular architecture for service robots. The proposed architecture has five key concepts which are different from conventional reconfigurable modular service robots; 1) easy and multiple assembly according to requirements of users, 2) hardware resource sharing system with other heterogeneous modules, 3) communication ability among all heterogeneous modules which have different operating systems, 4) automatic connection management system when a new module is attached, 5) automatic software upgrading system for new module software. We explain the three parts of the system architecture which meet the five concepts; mechanical architecture, software architecture, and connection architecture. To verify our architecture, we developed and evaluated a reconfigurable heterogeneous modular service robot by applying the proposed design.
THE TIME-INVARIANT LINEAR MIMO CHANNEL (2003)

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Differentiating agents facilitate infection of myeloid leukemia cell lines by monocytotropic HIV-1 strains [published erratum appears in Blood 1991 Apr 1;77(7):1624] (1990)

Monocytotropic human immunodeficiency virus type 1 (HIV-1) isolates from patients with acquired immunodeficiency syndrome (AIDS) infect mononuclear phagocytes as well as activated T cells, but do not usually infect immature human myeloid cell lines in vitro. The HL-60 promyelocytic/myeloblastic cell line and the promonocytic line, U937, were susceptible to productive infection by monocytotropic HIV-1 isolates (HIV-1JR-FL and HTLV-IIIBa-L) after treatment with retinoic acid, dimethyl sulfoxide, dibutyryl cAMP, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), or 12-O-tetradecanoyl-phorbol-13-acetate (TPA). Virus production was only detected when these compounds were added before virus infection. Virus replication did not correlate with CD4 receptor expression because undifferentiated HL-60 cells express CD4 and the level of CD4 expression did not increase after differentiation in the presence of retinoic acid, 1,25(OH)2D3, or TPA. A mature monocytic cell line (THP-1) was capable of infection without pretreatment, and treatment with differentiating agents enhanced virus production. A chronically infected cell line (J-HL-60) was isolated after HIV-1JR-FL infection of HL-60 cells treated with retinoic acid. Virus production in this cell line was enhanced more than 10-fold after differentiation in the presence of 1,25(OH)2D3 or TPA. The majority of virus production by 1,25(OH)2D3-treated J-HL-60 cells was associated with the mature, adherent population. Molecular analysis of a cloned line of J-HL-60 showed integration of a single DNA provirus. These results suggest that cellular factors associated with precursor cell differentiation along the myelomonocytic pathway are required for optimal replication of monocytotropic HIV-1 strains in vitro.
Quantum and statistical mechanical studies of liquids. Part 22. Pressure dependence of mixing enantiomeric liquids: 1,2-dichloropropane (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTQuantum and statistical mechanical studies of liquids. Part 22. Pressure dependence of mixing enantiomeric liquids: 1,2-dichloropropaneWilliam L. Jorgensen and Bernard BigotCite this: J. Phys. Chem. 1982, 86, 15, 2867–2873Publication Date (Print):July 1, 1982Publication History Published online1 May 2002Published inissue 1 July 1982https://pubs.acs.org/doi/10.1021/j100212a013https://doi.org/10.1021/j100212a013research-articleACS PublicationsRequest reuse permissionsArticle Views64Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
In Vitro Mechanical Properties of a Calcium Silicate Based Bone Void Filler (2006)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Rewiring Integrin-Mediated Signaling and Cellular Response with the Peripheral Myelin Protein 22 and Epithelial Membrane Protein 2 Components of the Tetraspan Web (2011)

Relative expression of EMP2 or PMP22 within the tetraspan web drives a cellular response toward a FAK- or AKT-dependent pathway, respectively. EMP2 and PMP22 differentially regulate collagen gel contraction in the ARPE-19 cell line. The implication of this finding adds a new dimension to the concept of the tetraspan web, in which the abundance of individual tetraspan family members differentially regulates signal transduction and the downstream cellular response.
Enhancing the image quality of high‐resolution MR angiography (1995)

Abstract In MR angiography, which is effective for screening of aneurysms, investigation for the quality of high‐resolution angiography method using the combination of asymmetric measurement with half scan reconstruction are presented. In addition to avoiding the flow void by the asymmetric measurement, it was found that there were improvements of: (1) blood contrast by isolation of small vessels and static regions; (2) blood continuation by interpolation in 3‐dimensional space; and (3) relative S/N of small vessels with the increasing resolution. Experimental results show that good contrast image is obtained by this method with no penalty of scanning time.
Activities of Ibaraki University in the North Ibaraki Geopark Project: Case Study on the Role of the University in Implementing the Geopark Project (2011)

The activities of Ibaraki University in the North Ibaraki Geopark Project mainly comprise designing the framework of the geostory, planning and carrying out geotours, training interpreters for the geosites and constructing an information network system using social networking service (SNS). In this paper we present a case study on the role of the university in the geopark project. The activities of the academic staff and a project team made up of undergraduate and the graduate students of Ibaraki University using geological information for the North Ibaraki Geopark Project is explained. Ibaraki University promotes the geopark project and thus contributes to the regional development in the northern Ibaraki area.
Gas-phase electrolysis of hydrobromic acid. (1986)

熱化学水素製造プロセスの基本反応の一つであるHBrの分解について, 黒鉛製の燃料電池型電解セルを用いた気相電解法の検討を行なった。電解質には85wt%リン酸を, 電極にはグラファイトフェルトを用い, 貴金属 (Pt, Pd, Rh, Ru) を触媒として担持した。これらのうち白金を含浸法により担持した場合がもっとも高い電極性能を示した。また, 約0.1mg/cm2までは白金担持量とともに性能は向上したが, それ以上での担持効果は小さかった。HBr分圧は高くするほど電流密度, HBr電解率ともに向上し, 15kPa,槽電圧Q.80vにおいてそれぞれ90mA/cm2, 17%を示した。電解温度を398～453Kの範囲で変えた場合, 電極性能にほとんど変化はなく, 電流効率もほぼ100%を示した。さらに, 白金線電極を参照電極として用いることにより得られたアノード, カソードの各分極曲線から, 白金の添加効果はカソード側でとくに大きいことが判明した。実際に, 白金を1mg/cm2担持した電極を用い, 423K, 槽電圧0.80Vにおいて20時間の連続電解を行なった結果, 15時間まではほぼ安定した電流密度を示すが, それ以上ではセル抵抗の増加により電流密度はやや低下することがわかった。
Conformal mappings to achieve simple material parameters for transformation optics devices (2009)

The transformation optics technique for designing novel electromagnetic and optical devices offers great control over wave behavior, but is difficult to implement primarily due to limitations in current metamaterial design and fabrication techniques. This paper demonstrates that restricting the spatial transformation to a conformal mapping can lead to much simpler material parameters for more practical implementation. As an example, a flat cylindrical-to-plane-wave conversion lens is presented and its performance validated through numerical simulations. It is shown that the lens dimensions and embedded source location can be adjusted to produce one, two, or four highly directive planar beams. Two metamaterial designs for this lens that implement the required effective medium parameters are proposed and their behavior analyzed.
Influence of molecular structure on the performance of low Voc loss polymer solar cells (2016)

Two regioregular narrow bandgap conjugated polymers (PM1 and PM2) are prepared and their devices exhibit low <italic>V</italic><sub>oc</sub> loss and high short circuit current <italic>J</italic><sub>sc</sub>, but, most significantly, display improved fill factors compared to previously reported PIPCP.
Strong Screening Effect of Photo-Generated Carriers on Piezoelectric Field in In0.13Ga0.87N/In0.03Ga0.97N Quantum Wells (2002)

We report the strong screening effect of photo-generated carriers on piezoelectric field induced by lattice mismatch strain in In0.13Ga0.87N/In0.03Ga0.97N multiple quantum wells. Blue shifts as large as 83 meV and 120 meV of intrinsic transitions at 4 K and 80 K, respectively, are observed when excitation power is increased by two orders of magnitude. Self-consistent numerical calculations were carried out that involved simultaneously solving Schrödinger's and Poisson's equations in order to interpret the experimental data. Efficient screening of the huge piezoelectric field by photo-generated carriers in quantum well regions is demonstrated both experimentally and theoretically.
Effects of C/O Ratio and Temperature on Sooting Limits of Spherical Diffusion Flames (2008)

Limiting conditions for soot particle inception in spherical diffusion flames were investigated numerically. The flames were modeled using a one-dimensional, time accurate diffusion flame code with detailed chemistry and transport and an optically thick radiation model. Seventeen normal and inverse flames were considered, covering a wide range of stoichiometric mixture fraction, adiabatic flame temperature, residence time and scalar dissipation rate. These flames were previously observed to reach their sooting limits after 2 s of microgravity. Sooting-limit diffusion flames with scalar dissipation rate lower than 2/s were found to have temperatures near 1400 K where C/O = 0.51, whereas flames with greater scalar dissipation rate required increased temperatures. This finding was valid across a broad range of fuel and oxidizer compositions and convection directions.
Inhibin A as a tumor marker for primary bilateral macronodular adrenal hyperplasia (2020)

PBMAH is a rare cause of CS. PBMAH may have an insidious presentation, allowing the disease to progress for years prior to diagnosis. Inhibin A is a heterodimeric glycoprotein hormone expressed in the gonads and adrenal cortex. Inhibin A serum concentrations are elevated in some patients with PBMAH, suggesting the potential use of this hormone as a tumor marker. Further exploration of serum inhibin A concentration, as it relates to PBMAH disease progression, is warranted to determine if this hormone could serve as an early detection marker and/or predictor of successful surgical treatment.
Subdiffraction Multicolor Imaging of the Nuclear Periphery with 3D Structured Illumination Microscopy (2008)

Fluorescence light microscopy allows multicolor visualization of cellular components with high specificity, but its utility has until recently been constrained by the intrinsic limit of spatial resolution. We applied three-dimensional structured illumination microscopy (3D-SIM) to circumvent this limit and to study the mammalian nucleus. By simultaneously imaging chromatin, nuclear lamina, and the nuclear pore complex (NPC), we observed several features that escape detection by conventional microscopy. We could resolve single NPCs that colocalized with channels in the lamin network and peripheral heterochromatin. We could differentially localize distinct NPC components and detect double-layered invaginations of the nuclear envelope in prophase as previously seen only by electron microscopy. Multicolor 3D-SIM opens new and facile possibilities to analyze subcellular structures beyond the diffraction limit of the emitted light.
Figure 1 from Somatic Mosaic Chromosomal Alterations and Death of Cardiovascular Disease Causes among Cancer Survivors (2023)

&lt;p&gt;Visual representation of the study flow. Of participants with genotyping and genome-wide mCA detection information available within the UK Biobank, we focused on those with a cancer diagnosis. The exposure of interest (mCA) was assessed for the risks of death of CVD causes, death of CAD causes, death of cancer causes, and death of any cause. The risk of various incident CV phenotypes were considered as exploratory endpoints.&lt;/p&gt;
Abstract 1547: DNA-encoded bispecific T-cell engagers and antibodies present long-term antitumor activity (2019)

Abstract Specific antibody therapy, including monoclonal antibodies and bispecific T cell engagers (BiTEs), are important new tools for cancer immunotherapy. However, these approaches are slow to develop and may be limited in their production thus restricting the patients who can access these treatments. BiTEs exhibit a particularly short half-life and difficult production. The development of an approach allowing simplified development, delivery and in vivo production would be an important advance. Here we describe development of a designed synthetic DNA plasmid, which we optimized to permit high expression of an anti-HER2 antibody (HER2DMAb) and delivered it into animals through adaptive electroporation. HER2DMAb was efficiently expressed in vitro and in vivo, reaching levels of 50ug/ml in mouse sera. Mechanistically, HER2DMAb blocked HER2 signaling and induced antibody-dependent cytotoxicity. HER2DMAb delayed tumor progression for HER2-expressing ovarian and breast cancer models. We next used the HER2DMAb scFv portion to engineer a DNA-encoded BiTE. This HER2DBiTE was expressed in vivo for approximately 4 months after a single administration. The HER2DBiTE was highly cytolytic and delayed cancer progression in mice. These studies illustrate a novel approach to generate DBiTEs in vivo which represent promising immunotherapies for HER2+ tumors including ovarian and potentially other cancers. Citation Format: Alfredo Perales-Puchalt, Elizabeth K. Duperret, Kar Muthumani, David B. Weiner, Xue Yang, Xizhou Zhu, Krzysztof Wojtak, Edgar Tello-Ruiz, Megan C. Wise. DNA-encoded bispecific T-cell engagers and antibodies present long-term antitumor activity [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 1547.
Experimental Studies With a 9F Forward-Looking Intracardiac Imaging and Ablation Catheter (2009)

The imaging resolution performance of this very small array device, together with its penetration beyond 2 cm, is excellent considering its very small array aperture. The forward-looking intracardiac catheter has been adapted to work easily on an existing commercial imaging platform with very minor software modifications.
Binding of Urokinase to Low Density Lipoprotein-related Receptor (LRP) Regulates Vascular Smooth Muscle Cell Contraction (2002)

Urokinase plasminogen activator (uPA) is a multifunctional protein that has been implicated in several physiological and pathological processes involving cell adhesion and migration in addition to fibrinolysis. In a previous study we found that two-chain urokinase plasminogen activator (tcuPA) stimulates phenylephrine-induced vasoconstriction of isolated rat aortic rings. In the present paper we report that uPA(-/-) mice have a significantly lower mean arterial blood pressure than do wild type mice and that aortic rings from uPA(-/-) mice show an attenuated contractile response to phenylephrine. In contrast, the blood pressure of urokinase receptor knockout (uPAR(-/-)) mice and the response of their isolated aortic rings to phenylephrine were normal, indicating that the effect of uPA on vascular contraction is independent of uPAR. Addition of mouse and human uPA almost completely reversed both the impaired vascular contractility and the lower arterial blood pressure in vivo. The in vitro and in vivo effects of infused uPA on aortic contractility and the restoration of normal blood pressure in uPA(-/-) mice were prevented by antibody to low-density lipoprotein receptor-related protein/alpha(2)-macroglobulin receptor (LRP). A modified form of uPA that lacks the kringle failed to restore the blood pressure in uPA(-/-) mice, notwithstanding having a longer half-life in the circulation. Ligands that regulate the interaction of uPA with LRP, such as PAI-1 or the PAI-1-derived peptide (EEIIMD), abolished the vasoactivity of tcuPA in vitro and in vivo. These studies identify a novel signal transducing cellular receptor pathway involved in the regulation of vascular contractility.
Insulin improves heart function and metabolism during non-ischemic cardiogenic shock in awake canines (1997)

Insulin improves systolic and diastolic heart function during aerobic shock and accelerates in-vivo myocardial lactate oxidation.
Dendritic cell maturation is induced by mycoplasma infection but not by necrotic cells (2000)

To identify environmental stimuli that induce dendritic cell (DC) maturation, we exposed human monocyte-derived immature DC to apoptotic or necrotic cells and measured the levels of expression of costimulatory molecules and cytokine production. While most necrotic or apoptotic cells did not have any effect, some induced DC maturation as detected by up-regulation of CD83 and B7.2 and production of IL-12 and IL-6. The capacity of these cell lines to induce DC maturation was due to their contamination by mycoplasma, since the maturation-inducing effect disappeared when the cells were treated with cyproxin. Furthermore, cell lines deliberately infected with mycoplasma containing supernatant acquired the capacity to induce DC maturation. Our results reveal that DC are able to sense mycoplasma infection and mature as they do in response to most viruses and bacteria. In contrast, apoptotic or necrotic cells fail to induce DC maturation.
Multifunctional Tactile Sensors: A Highly Sensitive Tactile Sensor Using a Pyramid‐Plug Structure for Detecting Pressure, Shear Force, and Torsion (Adv. Mater. Technol. 3/2019) (2019)

In article number 1800284, Jang-Yeon Kwon and co-workers demonstrate highly sensitive tactile sensors using a pyramid-plug structure that enables them to detect pressure, shear force, and torsion. The wide operating range of the sensor, from soft breathing to arbitrary multiplex touching, makes it particularly promising for future applications.
Spectrin-like repeats from dystrophin and alpha-actinin-2 are not functionally interchangeable (2002)

Mutations in the dystrophin gene result in Duchenne muscular dystrophy (DMD). Dystrophin is a multidomain protein that functions to stabilize the sarcolemmal membrane during muscle contraction. The central rod domain has been proposed to act as a shock absorber, as a force transducer or as a spacer separating important N- and C-terminal domains that interact with actin and the dystrophin-glycoprotein complex (DGC). Structure/function studies demonstrated that deletion of large portions of the rod domain can result in the production of smaller, yet highly functional, dystrophin proteins. In a dramatic example, a 'micro-dystrophin' transgene containing only four dystrophin spectrin-like repeats resulted in complete correction of most of the symptoms associated with dystrophy in the mdx mouse model for DMD. Dystrophin shares considerable homology with the multidomain, actin-crosslinking protein alpha-actinin. To explore the hypothesis that the dystrophin rod domain acts as a spacer region, a chimeric micro-dystrophin transgene containing the four-repeat rod domain of alpha-actinin-2 was expressed in mdx mice. This chimeric transgene was incapable of correcting the morphological pathology of the mdx mouse, but still functioned to assemble the DGC at the membrane and provided some protection from contraction-induced injury. These data demonstrated that different spectrin-like repeats are not equivalent, and reinforced the suggestion that the dystrophin rod domain is not merely a spacer but likely contributes an important mechanical role to overall dystrophin function.
Simultaneous Dehalogenation and Removal of Persistent Halocarbon Pesticides from Water Using Graphene Nanocomposites: A Case Study of Lindane (2015)

This paper describes an unusual chemical reaction that takes place on a graphene composite in a concerted fashion. The reaction shows the conversion of a persistent organochlorine pesticide, lindane (C6H6Cl6), present in water, to different isomers of trichlorobenzenes (TCBs, C6H3Cl3) on the surface of reduced graphene oxide–silver composites (RGO@Ag). The reaction is unique to the composite and does not occur on RGO and nanoparticles of Ag separately. The products of the reaction were isolated and extensively characterized using analytical techniques such as gas chromatography–mass spectrometry, electrospray ionization mass spectrometry, infrared and NMR, which unequivocally confirmed their identity. The as-formed TCBs were removed from the aqueous medium by adsorption on the same composite. Adsorption of lindane is physical in nature, but that of TCBs is through π–π interactions. The study reveals the unusual chemical reactivity of graphene–metal composites and their potential for water treatment. The uniqueness of the reaction on RGO@Ag is due to the simultaneous removal of three HCl molecules, leading to the formation of aromatic compounds and concomitant formation of silver chloride. Recycling capacity and effect of diverse species present in natural waters were tested for potential applications in sustainable water treatment.
Elevated levels of von Hippel‐Lindau protein in human and mouse fibrotic lungs (2009)

Objective Fibronectin (FN) deposition and fibroproliferation contribute to pulmonary fibrosis. von Hippel‐Lindau protein (pVHL) regulates assembly of fibronectin matrix. We sought to determine whether pVHL participates in pulmonary fibrosis. Methods and Results We found that lungs from idiopathic pulmonary fibrosis (IPF) patients expressed higher levels of pVHL mRNA and protein as measured by quantitative real time RT‐PCR (qRT‐PCR) and Western blot analysis. We also discovered that lungs from IPF patients displayed strong staining of pVHL in fibrotic foci upon immunohistochemistry analysis. In the bleomycin‐induced mouse model, fibrotic lungs exhibited increased levels of pVHL mRNA and protein as determined by qRT‐PCR and immunofluorescence staining. Overexpression of exogenous pVHL stimulated proliferation of primary rat and human lung fibroblasts and increased FN expression, assembly and phosphorylation of focal adhesion kinase (FAK). Conclusions Our results suggest that fibrotic lungs have increased pVHL expression and overexpression of pVHL increases FN/integrin/FAK signaling, resulting in fibroproliferation and fibrosis.This study is supported by NIH HL‐071643, AR‐042309 and Parker B. Francis foundation.