gebhart/patrepeval huggingface dataset:
A Variational Bayes Approach to Adaptive Radio Tomography (2020)

Radio tomographic imaging (RTI) is an emerging technology for localization of physical objects in a geographical area covered by wireless networks. With attenuation measurements collected at spatially distributed sensors, RTI capitalizes on spatial loss fields (SLFs) measuring the absorption of radio frequency waves at spatial locations along the propagation path. These SLFs can be utilized for interference management in wireless communication networks, environmental monitoring, and survivor localization after natural disasters such as earthquakes. Key to the success of RTI is to accurately model shadowing as the weighted line integral of the SLF. To learn the SLF exhibiting statistical heterogeneity induced by spatially diverse environments, the present work develops a Bayesian framework entailing a piecewise homogeneous SLF with an underlying hidden Markov random field model. Utilizing variational Bayes techniques, the novel approach yields efficient field estimators at affordable complexity. A data-adaptive sensor selection strategy is also introduced to collect informative measurements for effective reconstruction of the SLF. Numerical tests using synthetic and real datasets demonstrate the capabilities of the proposed approach to radio tomography and channel-gain estimation.
Substrate Specificity of Mammalian N-Terminal α-Amino Methyltransferase NRMT (2012)

N-Terminal methylation of free α-amino groups is a post-translational modification of proteins that was first described 30 years ago but has been studied very little. In this modification, the initiating M residue is cleaved and the exposed α-amino group is mono-, di-, or trimethylated by NRMT, a recently identified N-terminal methyltransferase. Currently, all known eukaryotic α-amino-methylated proteins have a unique N-terminal motif, M-X-P-K, where X is A, P, or S. NRMT can also methylate artificial substrates in vitro in which X is G, F, Y, C, M, K, R, N, Q, or H. Methylation efficiencies of N-terminal amino acids are variable with respect to the identity of X. Here we use in vitro peptide methylation assays and substrate immunoprecipitations to show that the canonical M-X-P-K methylation motif is not the only one recognized by NRMT. We predict that N-terminal methylation is a widespread post-translational modification and that there is interplay between N-terminal acetylation and N-terminal methylation. We also use isothermal calorimetry experiments to demonstrate that NRMT can efficiently recognize and bind to its fully methylated products.
Resolvability of the Multiple Access Channel with Two-Sided Cooperation (2020)

We study the randomness required at the inputs of a multiple access channel in order to produce a desired, approximately i.i.d., output distribution, subject to cooperation in one of the following forms: (i) a common message, (ii) conferencing, (iii) feedback and (iv) generalized feedback. For the cases (i)-(iii), we characterize the channel resolvability via matching inner and outer bounds, and for generalized feedback we provide two inner bounds representing the role of decoding and randomness extraction, which can also be combined. One of the main contributions of this work is to show that resolvability rates of the multiple access channel are not improved with feedback, unlike the multiple access channel capacity which is improved by feedback.
Nanobiomolekulare Multiproteinarchitekturen zur Etablierung von schaltbaren Signalketten auf Elektroden (2014)

Abstract Aus drei Proteinkomponenten wird eine supramolekulare Proteinarchitektur auf Elektroden aufgebaut. Damit kann eine bidirektionale Elektronentransferkaskade infolge intermolekularen Elektronentransfers etabliert werden. Der supramolekulare Aufbau im Multischichtformat wird durch das Einbetten zweier unterschiedlicher Enzyme (Cellobiosedehydrogenase und Laccase), sowie eines Redoxproteins (Cytochrom c ) mittels carboxymodifizierten Siliciumdioxidnanopartikeln realisiert. Das Multiproteinsystem ermöglicht die duale Detektion zweier unterschiedlicher Analyte: Laktose und Sauerstoff. Die Kontrolle der Enzymaktivität – das heißt, das selektive Anschalten der Bioelektrokatalyse – wird durch das angelegte Potential erreicht, da hierdurch der Redoxzustand von Cytochrom c vorgegeben wird. Die beiden bidirektionalen Signalketten arbeiten in einer unseparierten Matrix, ohne dass die Anwesenheit des anderen Biokatalysators störend wirkt.
Fabrication and characterization of copper oxide-silicon nanowire heterojunction photodiodes (2014)

In this study, copper oxide (CuO) thin film/silicon (Si) nanowire heterojunctions have been fabricated and their optoelectronic performances have been investigated. Vertically aligned n-type Si nanowires have been fabricated using metal-assisted etching (MAE) technique. CuO thin films were synthesized by the sol-gel method and deposited onto the nanowires through spin-coating. Fabricated nanowire heterojunction devices exhibited excellent diode behaviour compared to the planar heterojunction control device. The rectification ratios were found to be 105 and 101 for nanowire and planar heterojunctions, respectively. The improved electrical properties and photosensitivity of the nanowire heterojunction diode was observed, which was related to the three-dimensional nature of the interface between the Si nanowires and the CuO film. Results obtained in this work reveal the potential of Si nanowire-based heterojunctions for various optoelectronic devices.
Simulation of the Radar Cross-Section of Wake Vortices in clear air (2012)

Real-time sensing of Wake Vortices at take-off and landing is a key issue for the implementation of new air traffic management systems for reduced aircraft separation in favourable weather conditions and for increased air safety. In the framework of SESAR P12.2.2 project, a model has been developed at UCL for the calculation of the radar cross-section of the wake vortices, in a wide frequency range. The first step is the simulation of the evolution of pressure, temperature and humidity versus time, during the landing phase of the aircraft. These parameters are calculated using a pseudo-spectral code developed at UCL and then used for the calculation of the refractive index of the atmosphere under stratified conditions. They are represented in a plane perpendicular to the airplane velocity and evolving with time. The next step is the calculation of the radar cross-section of the various elements of the 3D-grid. The integrand is composed of a rapidly oscillating function in the frequency range of interest. The method of Li (1) has been implemented for the resolution of the integral. The integration method necessitates interpolation between the elements of the grid. Simulations can be calculated for various airplanes weight and span, various speeds, various stratifications of the atmosphere, represented by Brunt-Vaisala constant. 2. Detection of wake vortices using radar
On the Scalability of HeapCheck (2022)

In our DSN 2021 paper, we introduced HeapCheck, a combination of hardware and software that provides strong protection against memory-safety vulnerabilities with minimal performance overhead. In this short paper, we discuss how HeapCheck can support programs that use very large numbers of objects, and we also compare HeapCheck to two recently announced industry approaches to memory-safety.
Status of Cytomegalovirus Prevention and Treatment in 2000 (2000)

Cytomegalovirus (CMV) infection continues to be a problem in selected populations following hematopoietic stem cell transplantation (SCT). Although there have been no new antiviral agents for management of this infection in recent years, the methods for using the existing agents have improved with newer assays for detection of virus. In addition, our understanding of immunity to CMV has undergone considerable expansion. This paper will address these new aspects relating to CMV infection in the setting of SCT. In Section I Dr. Zaia reviews the pathogenesis of CMV and the current epidemiology of CMV disease following marrow or blood allo-SCT with emphasis on late-onset disease. The current lab tests available for preemptive management are summarized including the role for conventional shell vial cultures, and a comparison of the CMV antigenemia assay with the new nucleic acid-based assays, including the hybrid capture assay, the NASBA assay, and “real-time” PCR assays. Use of antiviral agents with these tests in the preemptive management of CMV infection is discussed. Ultimately, what is necessary is restoration of adequate CMV immunity, and that requires understanding the basics of the CMV-specific immune response. In Section II, Dr. Sissons traces the evolution of the CTL response from primary infection into memory and reviews recent advances in the understanding of cytotoxic T cell based immunity to CMV, based on the use of T cell clonotypic analysis and markers of T cell memory and activation, with conventional CTL functional assays. In Section III Dr. Riddell presents approaches to correction of the problem of CMV pathogenesis, namely direct restoration of the CMV-specific cellular immune deficiency. Attempts at passive therapies will be reviewed with the focus on current problems and approaches to these problems. In Section IV, Dr. Diamond presents work on the identification of multiple HLA-allele specific cytotoxic T cell epitopes specific for CMV-pp65 and - pp150. Specific epitopes are recognized by CMV-seropositive individuals including healthy donors, SCT recipients, and AIDS patients, indicating their potential usefulness as vaccines. One of these epitopes is recognized by most individuals who express the HLA A*0201 Class I allele. Pre-clinical evaluation in HLA2.1 transgenic mice of vaccine structures utilizing this epitope, and alternative delivery systems are described. Possible methods for vaccination of donor and/or recipient of a SCT as well as their limitations, utilizing synthetic or viral vaccines, are discusseed.
Inline coherent imaging of laser micromachining (2010)

In applications ranging from noncontact microsurgery to semiconductor blind hole drilling, precise depth control of laser processing is a major challenge. Even expensive a priori characterization cannot compensate for material heterogeneity and stochasticity inherent to the ablation process. Here we use in situ depth imaging to guide the machining process in real time. W e image along the machining beam axis at high speeds (up to 300 kHz) to provide real-time feedback, even in high aspect ratio holes. The in situ metrology is based on coherent imaging (similar to optical coherence tomography) and is practical for a wide-range of light sources and machining processes (e.g., thermal cutting or ultrafast nonlinear ablation). Coherent imaging has a high dynamic range (>; 60 dB) and strongly rejects incoherent signals allowing weak features to be observed in the presence of intense machining light and plasmas. High axial resolution (~10 μm) requires broadband imaging light but the center wavelength can be chosen appropriate to the application. Infrared light (wavelength: 1320 ± 35 nm) allows simultaneous monitoring of both surface and subsurface interfaces in non-absorbing materials like tissue and semiconductors. By contrast, silicon based detector technology can be used with near infrared imaging light (805 ± 25 nm) enabling high speed acquisition and low cost implementation.
Canturrear (2022)

a medio cocinar, esa escena irrecobrable de la muchacha haciendo pan, de los días en que hubo muchachas que amasaban cuerpos para el horno como retratos de cicatrices, marcándoles
Circumnavigation Using Distance Measurements Under Slow Drift (2011)

Consider an agent A at an unknown location, undergoing sufficiently slow drift, and a mobile agent B that must move to the vicinity of and then circumnavigate A at a prescribed distance from A. In doing so, B can only measure its distance from A, and knows its own position in some reference frame. This paper considers this problem, which has applications to surveillance and orbit maintenance. In many of these applications it is difficult for B to directly sense the location of A, e.g. when all that B can sense is the intensity of a signal emitted by A. This intensity does, however provide a measure of the distance. We propose a nonlinear periodic continuous time control law that achieves the objective using this distance measurement. Fundamentally, a) B must exploit its motion to estimate the location of A, and b) use its best instantaneous estimate of where A resides, to move itself to achieve the circumnavigation objective. For a) we use an open loop algorithm formulated by us in an earlier paper. The key challenge tackled in this paper is to design a control law that closes the loop by marrrying the two goals. As long as the initial estimate of the source location is not coincident with the intial position of B, the algorithm is guaranteed to be exponentially convergent when A is stationary. Under the same condition, we establish that when A drifts with a sufficiently small, unknown velocity, B globally achieves its circumnavigation objective, to within a margin proportional to the drift velocity.
Very fast transient simulation and measurement methodology for ESD technology development (2009)

A Transient safe operating area (TSOA) definition for ESD applications is introduced. Within this concept framework, ESD protection device topologies developed in a mixed-signal submicron high-voltage CMOS technology are studied to identify turn-on voltage and the resulting voltage overshoot conditions during fast ESD transients. A state-of-the-art numerical simulation environment used to study and optimize the fast transient response of ESD protection devices is discussed and simulation results are benchmarked versus very fast transmission line pulsing measurements. Constraints for triggering control of clamp devices are also investigated via simulations and pulse measurements.
Emissionen aus Polymeren messen (2010)

Abstract Ob sich ein Kunststoff für eine Anwendung, etwa im Innenraum eines Autos, eignet, hängt auch davon ab, welche Substanzen er ausgast. Diese Emissionen lassen sich gaschromatographisch analysieren. Dafür eignen sich die statische Headspace‐ und die Thermodesorptions‐Gaschromatographie.
Asymptotic Analysis of the Performance of LAS Algorithm for Large-MIMO Detection (2008)

In our recent work, we reported an exhaustive study on the simulated bit error rate (BER) performance of a low-complexity likelihood ascent search (LAS) algorithm for detection in large multiple-input multiple-output (MIMO) systems with large number of antennas that achieve high spectral efficiencies. Though the algorithm was shown to achieve increasingly closer to near maximum-likelihood (ML) performance through simulations, no BER analysis was reported. Here, we extend our work on LAS and report an asymptotic BER analysis of the LAS algorithm in the large system limit, where $N_t,N_r \to \infty$ with $N_t=N_r$, where $N_t$ and $N_r$ are the number of transmit and receive antennas. We prove that the error performance of the LAS detector in V-BLAST with 4-QAM in i.i.d. Rayleigh fading converges to that of the ML detector as $N_t,N_r \to \infty$.
VH repertoire in progeny of long term lymphoid-cultured cells used to reconstitute immunodeficient mice. (1989)

VH gene utilization in the progeny of long term lymphoid-cultured cells used for reconstitution of severe combined immunodeficient mice under varying conditions was determined. Hybridomas made from the spleens of these animals were evaluated for clonality and donor origin and a panel of 146 independent hybridomas were subsequently examined for VH expression. Hybridomas derived from the spleens of SCID mice reconstituted with fresh cells, used as a control, utilized VH families in proportion to their numerical representation in the genome. However, hybridomas from the spleens of mice reconstituted with long term cultured cells utilized a predominance of the two VH gene families most proximal to JH, characteristic of cells early in B lymphocyte development. Coinjection of thymocytes with cultured fetal liver cells, to provide good levels of T lymphocytes, did not alter this pattern of VH utilization. Irradiation (3 Gy) of the mice before cultured cell injection, which leads to more complete reconstitution of the B cell compartment, was effective in removing this bias in the VH repertoire. Hybridomas derived from these mice expressed their VH genes more in proportion to family size, characteristic of cells later in B lymphocyte development. In this manner, long term lymphoid-cultured cells can be used to study the transitions that occur in VH repertoire expression which appear to be mediated by either B lymphocyte developmental microenvironment or population size.
Effect of Implantation Site on Hepatocytes Heterotopically Transplanted on Biodegradable Polymer Scaffolds (2003)

We investigated the engraftment of heterotopically transplanted hepatocytes in three sites: the subcutaneous space, the small intestinal mesentery, and the omentum to determine the optimal location for tissue-engineered liver constructs. Hepatocytes were isolated from inbred Lewis rats and placed on polymer constructs. Cell-polymer constructs were implanted into the subcutaneous space of the abdominal wall, the small intestinal mesentery, and the omentum of Lewis rats. One group of rats had undergone previous portacaval shunt. Animals were killed 2 or 4 weeks after implantation and the constructs were analyzed for engraftment, using computer-assisted morphometric analysis. Engraftment was greatest in the omentum with less engraftment in the mesentery. There was minimal engraftment in the subcutaneous space in all specimens. Prior portacaval shunt increased engraftment in the mesentery and the omentum, but not the subcutaneous space. The omentum is the most favorable bed for engraftment of hepatocyte-polymer tissue-engineered constructs and the addition of a portacaval shunt increases survival of transplanted hepatocytes in the omentum and mesentery.
Efficient Synthesis of Sivelestat Sodium Hydrate (2008)

Abstract An efficient and scaleable synthesis of sivelestat sodium hydrate has been developed.
Relationships between quantitative spinal cord MRI and retinal layers in multiple sclerosis (2015)

In this cross-sectional study of patients with MS, correlations exist between SC-MRI and retinal layers, and both exhibit independent relationships with clinical dysfunction. These findings suggest that the SC and optic nerve reflect ongoing global pathologic processes that supplement measures of whole-brain atrophy, highlighting the importance of combining measures from unique compartments to facilitate a thorough examination of regional and global disease processes that contribute to clinical disability in MS.
Immunocytochemical study on internalization of anti-carbohydrate monoclonal antibodies. (1994)

The fate of anti-tumor monoclonal antibodies (mAbs) after binding to the cell surface is one of the important factors for application of mAbs in therapy. For mAbs to remain on the cell surface for a long time is preferable character for complement-dependent cytotoxicity (CDC) and antibody-dependent cellular cytotoxicity (ADCC). On the other hand, quick internalization of mAbs into cytoplasm is advantageous for cytotoxic effects of toxins or cytotoxic drugs conjugated with mAbs. In this study we investigated the localization of anti-carbohydrate mAbs in vitro by immunocytochemical methods at the electron microscopic level. Anti-ganglioside GM3 mAb (mouse IgM) was localized both in cytoplasmic vesicles and on the cell surface membrane of mouse melanoma cells after incubation for 30 min at 37 degrees C. Anti-ganglioside GM2 mAb (mouse IgM), anti-ganglioside GD2 mAb (mouse IgG3) anti-ganglioside GD3 mAb (mouse IgG3) mainly existed on the cell surface of human small cell lung carcinoma cells, human neuroblastoma cells and human melanoma cells, respectively, after incubation for 30 min at 37 degrees C. On the other hand, anti-sialyl Lea mAb (mouse IgG1) was intensively incorporated into the cytoplasm of human colon tumor cells under the same conditions. Anti-ganglioside GD3 mAb and anti-sialyl Lea mAb were radiolabelled with 125Iodine and traced in in vitro culture. When the cells were incubated in the presence of the 125I-mAb for 90 min on ice, the ratio of intracellular counts to surface counts was 8/92 for anti-ganglioside GD3 mAb and 31/69 for anti-sialyl Lea mAb respectively. After the subsequent incubation for 60 min at 37 degrees C, the ratio altered to 13/87 for anti-ganglioside GD3 mAb and 54/46 for anti-sialyl Lea antigen mAb. This study suggested that internalization of anti-carbohydrate mAbs after the binding to the cell surface was different among the mAbs depending on the character of antigens. In conclusion, anti-ganglioside mAbs have beneficial characters for CDC or ADCC while anti-sialyl Lea mAb is suitable for immunoconjugates.
A Comparison of the Homomorphic Encryption Schemes FV and YASHE. (2014)

We conduct a theoretical and practical comparison of two Ring-LWE-based, scale-invariant, leveled homomorphic encryption schemes – Fan and Vercauteren’s adaptation of BGV and the YASHE scheme proposed by Bos, Lauter, Loftus and Naehrig. In particular, we explain how to choose parameters to ensure correctness and security against lattice attacks. Our parameter selection improves the approach of van de Pol and Smart to choose parameters for schemes based on the Ring-LWE problem by using the BKZ-2.0 simulation algorithm. We implemented both encryption schemes in C++, using the arithmetic library FLINT, and compared them in practice to assess their respective strengths and weaknesses. In particular, we performed a homomorphic evaluation of the lightweight block cipher SIMON. Combining block ciphers with homomorphic encryption allows to solve the gargantuan ciphertext expansion in cloud applications.
Cross coupling of allylic derivatives. 16. Regiochemistry of cross coupling of the isomeric (E,E)-3,5-heptadien-2-yl and (E,E)-2,5-heptadien-4-yl pivalates with organocopper and Grignard reagents (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCross coupling of allylic derivatives. 16. Regiochemistry of cross coupling of the isomeric (E,E)-3,5-heptadien-2-yl and (E,E)-2,5-heptadien-4-yl pivalates with organocopper and Grignard reagentsTed L. Underiner and Harlan L. GoeringCite this: J. Org. Chem. 1990, 55, 9, 2757–2761Publication Date (Print):April 1, 1990Publication History Published online1 May 2002Published inissue 1 April 1990https://pubs.acs.org/doi/10.1021/jo00296a037https://doi.org/10.1021/jo00296a037research-articleACS PublicationsRequest reuse permissionsArticle Views346Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts