gebhart/patrepeval huggingface dataset:
Optimal design for individualised passive assistance (2015)

Assistive devices are capable of restoring independence and function to people suffering from musculoskeletal impairments. Traditional assistive exoskeletons can be divided into active or passive devices depending on the method used to provide joint torques. The design of these devices often does not take into account the abilities of the individual leading to complex designs, joint misalignment and muscular atrophy due to over assistance at each joint.
Polarization anisotropy in nonpolar oriented GaN films studied by polarized photoreflectance spectroscopy (2007)

Abstract We have used polarized photoreflectance spectroscopy to study the electronic‐band‐structure modification of GaN films grown along different nonpolar orientations due to biaxial, anisotropic in‐plane strain. For nonpolar oriented films, the c ‐axis of GaN lies in the film plane. An unstrained, high‐quality C ‐plane GaN film is used to estimate the difference in the band gap energies between 10 K and room temperature. We use the crystal‐field and spin–orbit splitting energies and the deformation potential D 5 determined at low temperatures to calculate the transition energies and the polarization properties of nonpolar oriented films at room temperature using the k · p perturbation approach. The calculated transition energies and oscillator strengths are then compared to the experimentally obtained values. (© 2007 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)
Dual Effects of Growth Hormone (GH)-Releasing Hormone Isfusion in Normal Men: Somatotroph Desensitization and Increase in Releasable GH* (1986)

Continuous infusion of human GH-releasing hormone (GHRH) stimulates GH secretion in normal subjects, but a single supramaximal iv dose of GHRH thereafter elicits a diminished serum GH response compared to that after a saline infusion; the response to the single dose challenge is inversely related to the dose of GHRH previously infused. To determine if this attenuated GH response is a result of depletion of available GH or desensitization of the somatotroph, a 6-h infusion of saline or GHRH (10 ng/kg . min) was administered to 10 normal men, and an iv bolus dose of either GHRH (3.3 micrograms/kg) or regular insulin (0.15 U/kg) was given after 5.5 h of infusion. On both days of GHRH infusion, there was significant stimulation of GH secretion compared to that after saline infusion. The GH response to the supramaximal dose of GHRH was greater after saline infusion than after GHRH infusion, and the GH response to insulin-induced hypoglycemia was significantly greater after GHRH infusion compared with the responses on the other 3 study days. The greatest GH secretion occurred during GHRH infusion followed by insulin administration; therefore, pituitary reserve was not decreased by prior exposure to GHRH. These studies suggest that somatotrophs become partially refractory to GHRH stimulation over time, but remain responsive to an alternate stimulus of GH secretion. We suggest that the hypoglycemia-induced GH response occurs via a reduction in hypothalamic somatostatin secretion, and the attenuated GH response to the supramaximal GHRH dose after GHRH infusion probably represents either partial desensitization or down-regulation of the GHRH receptor.
Management of Tetralogy of Fallot With Unilateral Absence of Pulmonary Artery (2014)

Tetralogy of Fallot with unilateral absence of pulmonary artery (PA) is a rare congenital anomaly that has been reported in isolated case reports and small case series. There is no well-defined treatment algorithm for these patients, and repair has been associated with high mortality, although survival is improving in the more recent era. Recent reports suggest strict case selection criteria based on PA dimensions and size of the left ventricle.
Effect of a major histocompatibility complex class I peptide on insulin-like growth factor-I receptor internalization and biological signaling. (1993)

Previous studies have shown that a peptide derived from the murine major histocompatibility complex class 1 (MHC-1) antigen inhibits insulin receptor internalization and enhances insulin action. Consequently, we have studied the effect of this peptide [Dk-(62-85)] derived from the MHC-1 antigen on insulin-like growth factor-I (IGF-I) internalization and action. When Chinese hamster ovary cells that overexpress human IGF-I receptors were incubated in the presence or absence of 30 microM Dk-(62-85), IGF-I internalization was inhibited by 43.9 +/- 1.7% (P < 0.005). This inhibitory effect was dose responsive, with a half-maximal effect at 8 microM and a maximal effect at 30 microM. The peptide did not affect IGF-I receptor autophosphorylation or ligand-induced phosphorylation of an endogenous substrate, pp185, in vivo. When added alone, the peptide increased glucose transport into Chinese hamster ovary cells by 66.3 +/- 16.0%, whereas when the peptide was added together with IGF-I, ligand-stimulated glucose transport was inhibited. In conclusion, 1) the MHC-1-derived peptide Dk-(62-85) inhibits IGF-I internalization in a dose-responsive fashion; 2) Dk-(62-85) does not affect receptor kinase activity, as IGF-I receptor autophosphorylation and endogenous substrate phosphorylation are unaltered; and 3) Dk-(62-85) stimulates glucose transport by itself, but inhibits IGF-I stimulated transport.
Carbonylation of Methanol on Metal–Acid Zeolites: Evidence for a Mechanism Involving a Multisite Active Center (2007)

In Aktion beobachtet: Kombinierte IR- und MAS-NMR-spektroskopische Techniken wurden genutzt, um an der Carbonylierung von Methanol an Zeolithen (Mordenit) beteiligte Zwischenstufen nachzuweisen. Cu sowie Brønsted-saure Stellen beschleunigen die Carbonylierung gegenüber der metallfreien Probe (mit der vor allem Essigsäure gebildet wird), indem sie bevorzugt CO und Dimethylether an Cu adsorbieren, und liefern vorrangig Methylacetat. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2007/z700029_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Non-conventional technologies for fuel desulphurization (2008)

Refinery distillates, especially gas oil fractions contain considerable amounts of alkylated benzo-thiophene components which are most recalcitrant to desulphurization via classical hydrodesulfurisation. Fuel regulations continue to tighten worldwide in response to the need for cleaner air and refiners meet these regulations at a very significant cost. In fact, most refiners will need a major revamp of existing HDS medium pressure units or even install new grass root units. The need to cut the operational and capital costs has necessitated a renewed look into non-hydrogen consuming, low temperature and pressure processes for producing ultra low sulphur fuels. Non-conventional approaches for ultra low sulphur fuels (ULSF) belong either to oxidative or to selective adsorption routes. In oxidative routes, biodesulfurization (BDS) involving specialized bacteria and oxidation catalysed by chemical oxidants have been thoroughly investigated. BDS by genetically engineered strains has capability to produce ULSD having 20 volumes of fuel before needing regeneration to restore their activity. Small SARS systems are especially attractive at gas stations for fuel cell vehicles. This presentation will review the recent advancements in oxidative and adsorption technologies for fuel desulfurization. Some results obtained in the author's labs for process improvement in biodesulfurization of diesel fractions will also be discussed.
3D Characterization of an Intermetallic β/γ‐Titanium Aluminide Alloy (2013)

Intermetallic titanium aluminides have evolved into a lightweight alternative to nickel-based superalloys because of their good mechanical properties at elevated temperatures combined with a low density. Potential fields of application include aircraft and automobile engines. Microstructure strongly influences a material's mechanical properties. Although conventional 2D image analysis provides statistically secure information about the microstructure, a complete understanding of the 3D arrangement (e.g. phase's connectivity) is not accessible. In this study, 2D image analysis, EBSD and FIB/SEM tomography are employed to analyze the 3D microstructure of a β/γ-TiAl alloy with a nominal composition of Ti-44Al-7Mo-0.1B (in at%).
Photosensitive polynorbornene based dielectric. II. Sensitivity and spatial resolution (2004)

Abstract Photodefinable poly(decylnorbornene‐ co ‐epoxidenorbornene) copolymer has been developed as a dielectric material for electronic packaging applications. The photodefinition properties of the polymer are affected by the copolymer composition, the concentration of photoactive compound and the process conditions. In particular, ultra‐high contrast conditions were found to promote the fabrication of vertical sidewall structures. For photodefined structures, the vertical sidewalls were obtained at specific formulations and process conditions. Under different conditions, non‐vertical features were observed. Rutherford backscattering analysis (RBS), X‐ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), and scanning electron microscopy (SEM) were used to study the photodefinition properties. In this article, a mechanism based on the diffusion of photoactive compounds from the exposed area to the unexposed area is presented. The transport of photoactive compounds takes place through the free volume that results from solvent evaporation. The diffusion of the photoactive compounds to the surface of the polymer film results in a higher concentration of photogenerated acid at the surface. The movement of the photoactive compounds occurs in both the in‐plane and through‐plane directions. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 91: 3031–3039, 2004
Supplementation with ω3 polyunsaturated fatty acids decreases fasting insulin and hemoglobin A1c levels in healthy Mexican adults: the role of PPARγ2 P12A (2017)

The effects of polyunsaturated fatty acids (PUFA) contained in fish oil (FO) in glycemic control are not clear and perhaps are influenced by genetic variation in Peroxisome Proliferator‐Activated Receptor (PPAR) genes. The study aimed to analyze the effect of FO supplementation on glucose metabolism and inflammation according to PPARγ2 P12A genotypes in young Mexican adults. 191 apparently healthy, non‐smoking subjects between 18 and 40 years were included in a one‐arm study. Participants were supplemented with 2.7g/day of EPA+DHA, during six weeks. Dietary analysis, indicators for glucose metabolism, and markers for inflammation were analyzed before and after intervention. An overall increase in relative concentration of ω3 fatty acids in red blood cells (HS‐ω3 index) was observed in all subjects [2.6, (SD:±1.2), P &lt;0.001]. Mean fasting insulin and glycated hemoglobin (HbA1c%) were significantly decreased in all subjects [−0.547mlU/L,(SD:±10.29), P =0.034 and −0.07%,(SD:±0.3), P &lt;0.001 respectively], whereas there was no change in fasting glucose, adiponectin, apelin and inflammatory markers. Subjects carrying the minor allele of PPARγ2 P12A had higher responses in the reduction of fasting insulin (−19.8%, −2.3mlU/L, ±8.4). Interestingly, in subjects with lower supplementation than 2.7g/day (~1.8g/day) reductions in fasting insulin and HbA1c% from baseline remained significant ( P =0.019 and P &lt;0.001). The observed responses in fasting insulin and HbA1c% in the Mexican population give further evidence of the importance to FO supplementation in young people as an early step towards the prevention of cardiometabolic disease. Support or Funding Information The study was funded by Nestec.
Excellent silicon thickness uniformity on Ultra-Thin SOI for controlling Vt variation of FDSOI (2011)

Thickness uniformity of the Ultra Thin SOI (UTSOI) substrates is one of the key criteria to control Vt variation of the planar FDSOI devices. We present an evolutionary approach to SmartCut™ technology which already allows achieving a maximum total SOI layer thickness variation of less than ± 10 Å on preproduction volume. Total thickness variation of ± 5 Å is targeted.
Measurement of factors influencing the participation of patients with prostate cancer in clinical trials: a Canadian perspective (2007)

Men rated items related to awareness and acceptability as being the most important determinants to future enrolment in a clinical trial. Knowledge about what these men believe is important for their future participation in a clinical trial will help researchers to design protocols that address the needs of targeted patient groups.
Development of High Durability Dyes for Ink Jet Printing System and the Establishment of an Industrial Production Process (2009)

Water-soluble novel cyan and magenta dyes, which show high light-fastness and ozone-fastness on porous photo media, have been invented for ink jet printing system. Control of dye energy levels, removal of sensitive groups towards ozone, and acceleration of copper-phthalocyanine complex (CuPc) aggregation were the dominant factors to improve both ozone-fastness and light-fastness significantly. For the development of the CuPc cyan skeleton, alkyl sulfonyl groups, all of which were located at beta positions on the CuPc skeleton, were effective to improve fastness. For the development of the magenta skeleton, the combination of aniline-substituted pyridine coupling component and pyrazole diazonium component was inherently important skeleton to improve fastness.Regarding the production process of the novel CuPc dye, solvent effect, control of pH and dehydration reagent such as an orthoester were the dominant parameters to improve cyclization yield. In the novel magenta dye, both introduction of plural functional groups at the same time and development of a highly regioselective reaction for sulfonation were key synthetic processes to establish a successful synthetic route.
Dynamic behavior of dicobalt hexacarbonyl propargyl cations and their reactions with chiral nucleophiles (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDynamic behavior of dicobalt hexacarbonyl propargyl cations and their reactions with chiral nucleophilesStuart L. Schreiber, Michael T. Klimas, and Tarek SammakiaCite this: J. Am. Chem. Soc. 1987, 109, 19, 5749–5759Publication Date (Print):September 1, 1987Publication History Published online1 May 2002Published inissue 1 September 1987https://pubs.acs.org/doi/10.1021/ja00253a030https://doi.org/10.1021/ja00253a030research-articleACS PublicationsRequest reuse permissionsArticle Views923Altmetric-Citations154LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Allosteric Control of Self‐Assembly: Modulating the Formation of Guanine Quadruplexes through Orthogonal Aromatic Interactions (2007)

Stabilisatoren: Die kovalente Anbindung (A) einer Porphyrinkopfgruppe an einen guaninreichen Oligonucleotidstrang kann die Selbstorganisation zu DNA-Quadruplexen durch π-π-Wechselwirkungen der Porphyrine (B) verstärken. Über die Modulation dieser allosterischen Wechselwirkungen durch die Zugabe eines porphyrinkomplexierenden Cyclodextrinderivats ist ein hohes Maß an Kontrolle über die Bildung und Zerlegung der Guaninquadruplexe möglich (C und D). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2007/z701883_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Energy Minimization and ac Demagnetization in a Nanomagnet Array (2008)

We study ac demagnetization in frustrated arrays of single-domain ferromagnetic islands, exhaustively resolving every (Ising-like) magnetic degree of freedom in the systems. Although the net moment of the arrays is brought near zero by a protocol with sufficiently small step size, the final magnetostatic energy of the demagnetized array continues to decrease for finer-stepped protocols and does not extrapolate to the ground-state energy. The resulting complex disordered magnetic state can be described by a maximum-entropy ensemble constrained to satisfy just nearest-neighbor correlations.
Guidelines for reasonable and appropriate care in the emergency department (GRACE): Recurrent, low‐risk chest pain in the emergency department (2021)

This first Guideline for Reasonable and Appropriate Care in the Emergency Department (GRACE-1) from the Society for Academic Emergency Medicine is on the topic: Recurrent, Low-risk Chest Pain in the Emergency Department. The multidisciplinary guideline panel used The Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to assess the certainty of evidence and strength of recommendations regarding eight priority questions for adult patients with recurrent, low-risk chest pain and have derived the following evidence based recommendations: (1) for those >3 h chest pain duration we suggest a single, high-sensitivity troponin below a validated threshold to reasonably exclude acute coronary syndrome (ACS) within 30 days; (2) for those with a normal stress test within the previous 12 months, we do not recommend repeat routine stress testing as a means to decrease rates of major adverse cardiac events at 30 days; (3) insufficient evidence to recommend hospitalization (either standard inpatient admission or observation stay) versus discharge as a strategy to mitigate major adverse cardiac events within 30 days; (4) for those with non-obstructive (<50% stenosis) coronary artery disease (CAD) on prior angiography within 5 years, we suggest referral for expedited outpatient testing as warranted rather than admission for inpatient evaluation; (5) for those with no occlusive CAD (0% stenosis) on prior angiography within 5 years, we recommend referral for expedited outpatient testing as warranted rather than admission for inpatient evaluation; (6) for those with a prior coronary computed tomographic angiography within the past 2 years with no coronary stenosis, we suggest no further diagnostic testing other than a single, normal high-sensitivity troponin below a validated threshold to exclude ACS within that 2 year time frame; (7) we suggest the use of depression and anxiety screening tools as these might have an effect on healthcare use and return emergency department (ED) visits; and (8) we suggest referral for anxiety or depression management, as this might have an impact on healthcare use and return ED visits.
Wolffia globosa–Mankai Plant-Based Protein Contains Bioactive Vitamin B12 and Is Well Absorbed in Humans (2020)

Mankai plant contains bioactive B<sub>12</sub> compounds and could serve as a B<sub>12</sub> plant-based food source.
Steroidal Mineralocorticoid Receptor Antagonists: Synthesis and Biology (2017)

Abstract The development of selective steroidal mineralocorticoid receptor antagonists with improved pharmacological profiles over existing marketed drugs is an attractive goal. Such compounds offer potential for the treatment of hypertension, heart failure and renal disease. With this aim, new spirolactones were prepared exploring substitutions at carbons 6, 7, 9–11, 15–16 and 21. Spirolactones 11 a and 20 were identified with promising biological profiles. Both compounds restored Na + /K + ratios to physiological levels in an in vivo model
Polymer Materials Science (2006)

No AccessPolymer ProcessingApr 2006Polymer Materials ScienceTim A. Osswald, Juan P. Hernández-OrtizTim A. Osswald, Juan P. Hernández-Ortizhttps://doi.org/10.3139/9783446412866.001SectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF key 'share (en)' returned an object instead of string.FacebookTwitterEmailLinkedIn previous chapternext chapter FiguresReferencesRelatedDetails 2006Pages: 1-36Print ISBN: 978-3-446-40381-9eISBN: 978-3-446-41286-6 Copyright & Permissions© 2006 Carl Hanser Verlag GmbH & Co. KGPDF downloadLoading ...
ChemInform Abstract: SYNTHESIS AND CENTRAL NERVOUS SYSTEM ACTIVITIES OF CERTAIN FLUORINE‐CONTAINING 3‐SUBSTITUTED INDOL‐2‐ONES (1984)

Abstract Aus Fluoranilinen (I) werden über die Isonitrosoacetanilide (II) Fluorindoldione (III) hergestellt.
Design and implementation of a deep learning model for Fraud Detection System(FDS) (2021)

금융회사들은 나날이 발전하는 전자금융기술과 이를 악용하는 공격기술에 대응하기 위해 이상금융거래시스템(아하 FDS) 을 운영하고 있다. 전자금융 이상거래와 전기통신 금융사기의 탐지 및 대응을 위해 기존 FDS는 시나리오 기반 탐지룰 즉, 블 랙리스트(Black List) 기반으로 운영하고 있으나 이를 교묘하게 우회하는 공격에 대해서는 대응에 한계가 있다. 이에 금융회사 들은 기존 FDS에 인공지능(AI) 기술을 접목하여 대응 강화를 모색하고 있다. 본 논문에서는 FDS에 적용할 수 있는 딥러닝 모델을 설계하고 구현한다. 본 논문에서 제안하는 FDS를 위한 딥러닝 모델은 비지도학습 기반인 Auto Encoder과 지도학습 기반인 DNN을 연계한 모델이다. Auto Encoder의 데이터의 복원률을 통해서 이상거래를 분류하고 이를 시나리오 룰 기반의 DNN 검증을 통해 이상금융거래를 탐지하고 대응한다. 본 모델은 지속적인 학습을 통해 탐지의 정확도를 높이고 이상금융거 래 대응을 강화할 수 있다.
Bacteria Coated by Polyphenols Acquire Potent Oxidant-Scavenging Capacities (2009)

Several microbial species, including probiotic lactic acid bacteria, have the ability to irreversibly bind a large variety of polyphenols (flavonoids) and anthocyanidins found in many colored fruits and vegetables and to enhance their total oxidant-scavenging capacities (TOSC). The binding of flavonoids to microbial surfaces was further increased by the cationic polyelectrolytes ligands poly-L-histidine, chlorhexidine and Copaxone. This phenomenon was confirmed visually, by the FRAP, DPPH, cyclic voltammetry, Folin-Ciocalteu as well as by luminol-dependent chemiluminescence techniques employed to assay TOSC. The possibility is considered that clinically, microbial cells in the oral cavity and in the gastro intestinal tract, complexed with antioxidant polyphenols from nutrients and with cationic ligands, might increase the protection of mammalian cells against damage induced by excessive generation of reactive oxygen species during infections and inflammation.