gebhart/patrepeval huggingface dataset:
An integrated wireless indoor navigation system for visually impaired (2011)

This paper presents an integrated wireless system that helps a visually impaired person navigate within an indoor environment. The guidance process to help the person navigate uses a ZigBee wireless mesh network to localize the user and a compass to determine his/her orientation. The system uses a server to calculate an optimal path from the user's present location to the target location or item to be reached. The system receives voice commands from the visually impaired person and generates audio responses to guide the person. The mobile unit of the system is compact and requires relatively low power. Overall the system has minimal intrusion level and the results of various testing scenarios showed it was successful. The results also showed that the accuracy level depends on the available ZigBee modules within the mesh network and the particular zone.
Expression and function of c-kit in hemopoietic progenitor cells. (1991)

The expression and function of a receptor tyrosine kinase, c-kit, in the adult bone marrow of the mouse were investigated by using monoclonal antibodies (mAbs) against the extracellular domain of murine c-kit. In adult C57BL/6 mouse, 7.8% of total bone marrow cells express c-kit on their surface. Half of the c-kit+ cells do not express lineage markers including Mac-1, Gr-1, TER-119, and B220, while the remainder coexpress myeloid lineage markers such as Mac-1 and Gr-1. After c-kit+ cells were removed from the bone marrow cell preparation, hemopoietic progenitor cells reactive to IL-3, GM-CSF, or M-CSF and also those which give rise to spleen colonies in irradiated recipients disappeared almost completely. Thus, most hemopoietic progenitors in the adult bone marrow express c-kit. To investigate whether or not c-kit has any role in the hemopoiesis of adult bone marrow, we took the advantage of one of the anti-c-kit mAbs that can antagonize the function of c-kit. As early as two days after the injection of 1 milligram of an antagonistic antibody, ACK2, almost all hemopoietic progenitor cells disappeared from the bone marrow, which eventually resulted in the absence of mature myeloid and erythroid cells in the bone marrow. These results provide direct evidence that c-kit is an essential molecule for constitutive intramarrow hemopoiesis, especially for the self-renewal of hemopoietic progenitor cells at various stages of differentiation.
Alternating phase-shifted mask for logic gate levels, design, and mask manufacturing (1999)

While the benefits of alternating phase shifted masks in improving lithographic process windows at increased resolution are well known throughout the lithography community, broad implementation of this potentially powerful technique has been slow due to the inherent complexity of the layout design and mask manufacturing process. This paper will review a project undertaken at IBM's Semiconductor Research and Development Center and Mask Manufacturing and Development facility to understand the technical and logistical issues associated with the application of alternating phase shifted mask technology to the gate level of a full microprocessor chip. The work presented here depicts an important milestone toward integration of alternating phase shifted masks into the manufacturing process by demonstrating an automated design solution and yielding a functional alternating phase shifted mask. The design conversion of the microprocessor gate level to a conjugate twin shifter alternating phase shift layout was accomplished with IBM's internal design system that automatically scaled the design, added required phase regions, and resolved phase conflicts. The subsequent fabrication of a nearly defect free phase shifted mask, as verified by SEM based die to die inspection, highlights the maturity of the alternating phase shifted mask manufacturing process in IBM's internal mask facility. Well defined and recognized challenges in mask inspection and repair remain and the layout of alternating phase shifted masks present a design and data preparation overhead, but the data presented here demonstrate the feasibility of designing and building manufacturing quality alternating phase shifted masks for the gate level of a microprocessor.
Diurnality, Type 2 Diabetes, and Depressive-Like Behavior (2018)

Although type 2 diabetes (T2DM) and depression are associated with disturbances in circadian rhythms, most studies of these diseases use nocturnal mice and rats while modeling diurnal humans. We suggest that the development of T2DM and depression are related to changes that accompany the switch from the mammalian ancestral nocturnal activity to the current diurnal one. We show that diurnal sand rats ( Psammomys obesus) held outdoors in laboratory cages (where they are exposed to natural environmental conditions) and fed a standard rodent diet do not develop T2DM in contrast to animals held indoors (where the only cycling environmental condition is light) fed the same diet. Moreover, keeping sand rats under a short photoperiod dampened behavioral and molecular daily rhythms, resulted in anxiety- and depressive-like behavior, and accelerated the development of T2DM. We suggest that the disturbed rhythms disrupt the internal temporal order and metabolic pathways controlled by feeding and the circadian system, resulting in the development of T2DM and depressive-like behavior. We further suggest that using nocturnal mice and rats as sole model animals may limit research, especially when studying circadian rhythm-related diseases.
Nanoplasmonic hydrogen sensing (2014)

In this review we discuss the evolution of surface plasmon resonance and localized surface plasmon resonance based hydrogen sensors. We put particular focus on how they are used to study metal-hydrogen interactions at the nanoscale, both at the ensemble and the single nanoparticle level. Such efforts are motivated by a fundamental interest in understanding the role of nanosizing on metal hydride formation processes. However, nanoplasmonic hydrogen sensors are not only of academic interest but may also find more practical use as all-optical gas detectors in industrial and medical applications, as well in a future hydrogen economy, where hydrogen is used as a carbon free energy carrier.
The t(8;14) breakpoint of the EW 36 undifferentiated lymphoma cell line lies 5' of MYC in a region prone to involvement in endemic Burkitt's lymphomas (1988)

One of the best analyzed tumor-specific cytogenetic abnormalities is the t(8;14) chromosomal translocation observed in cases of Burkitt's and undifferentiated lymphomas (ULs), and acute lymphoblastic leukemias (ALLs). Here we analyze the cloned (8;14) chromosomal breakpoint of the UL cell line EW 36. We show that the region of chromosome 8 involved in the translocation is situated near a site previously demonstrated to harbor a cluster of endemic Burkitt's lymphoma breakpoints, approximately 50 kb 5' of MYC. In those cases, we demonstrated that malfunction of the V-D-J recombinase generated the translocations. However, in this case the isotype switch mechanism of translocation is implicated: at the breakpoint, S mu/S gamma and C gamma sequences are found on chromosome 14. Thus, the features of the EW 36 t(8;14) breakpoint are consonant with our model for B-cell lymphomagenesis which relates the precursor cell that gives rise to malignancy, the mechanism of translocation, and the phenotype of the tumor.
RFC 5375: IPv6 Unicast address assignment considerations (2008)

One fundamental aspect of any IP communications infrastructure is its addressing plan. With its new address architecture and allocation policies, the introduction of IPv6 into a network means that network designers and operators need to reconsider their existing approaches to network addressing. Lack of guidelines on handling this aspect of network design could slow down the deployment and integration of IPv6. This document aims to provide the information and recommendations relevant to planning the addressing aspects of IPv6 deployments. The document also provides IPv6 addressing case studies for both an enterprise and an ISP network.
Expiratory Chest Compression for Atelectasis: No Harm, No Foul—Oops! (2004)

The only thing better than a well designed follow-up study that effectively addresses questions raised in earlier research is a study whose results are contrary to the authors’ hypothesis. So imagine my elation with the report by Unoki et al 1 in this issue of RESPIRATORY CARE.
Supplementary Data from Long-term Follow-up and Correlative Analysis of Two Phase II Trials of Rituximab and Lenalidomide Followed by Continuous Lenalidomide in Untreated and Relapsed/Refractory Indolent Lymphoma (2023)

&lt;p&gt;Supplemental Table 1&lt;/p&gt;
ChemInform Abstract: Arene 1,4‐Diradical Formation from o‐Dialkynylarenes. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Electronic transport properties of the perovskite-type oxides La1−xSrxCoO3±δ (2012)

La1−xSrxCoO3 is a leading candidate oxide electrode material for replacing standard metal electrodes. Here we investigate the origin of its high electronic conductivity by means of Rietveld analysis, Hall effect measurements, and band-structure calculations. A high electrical conductivity at room temperature, σ = 4.4 × 103 S cm−1 (which is the largest value for oxides that do not contain noble metals), was achieved by the substitution of 40–50 mol% Sr into the La sites, with a high carrier concentration of 4.5 × 1021 cm−3 and a carrier mobility of 5.8 cm2 V−1 s−1. The carrier concentration results from a trade-off between hole generation via Sr substitution and electron generation via oxygen deficiency. The high mobility arises from the small effective mass originating in the transition to a higher spin state.
Thermal Degradation Kinetics of Agaritine in Model Systems and Agaritine Retention in Canned Mushrooms (1985)

ABSTRACT The effects of heating and pH on agaritine degradation in buffer, mushroom puree and canned mushrooms were investigated. Ampules containing agaritine with citric‐phosphate buffer or agaritine with mushroom puree buffered with the same salts were heated for selected time intervals at temperatures ranging from 101‐133°C. Additionally, cans containing quartered mushrooms with brine and buffer were still‐retorted using five thermal process schedules with equivalent lethalities for Clostridium botulinum (F o values). In both the buffer and puree systems, agaritine degradation could be modeled by first‐order kinetics. In the canning study mushrooms processed for 68 min at 115°C contained about 23% less agaritine than those processed for 11 min at 127°C.
A parametric neutron Bragg edge imaging study of additively manufactured samples treated by laser shock peening (2021)

Laser powder bed fusion is an additive manufacturing technique extensively used for the production of metallic components. Despite this process has reached a status at which parts are produced with mechanical properties comparable to those from conventional production, it is still prone to introduce detrimental tensile residual stresses towards the surfaces along the building direction, implying negative consequences on fatigue life and resistance to crack formations. Laser shock peening (LSP) is a promising method adopted to compensate tensile residual stresses and to introduce beneficial compressive residual stress on the treated surfaces. Using neutron Bragg edge imaging, we perform a parametric study of LSP applied to 316L steel samples produced by laser powder bed fusion additive manufacturing. We include in the study the novel 3D-LSP technique, where samples are LSP treated also during the building process, at intermediate build layers. The LSP energy and spot overlap were set to either 1.0 or 1.5 J and 40[Formula: see text] or 80[Formula: see text] respectively. The results support the use of 3D-LSP treatment with the higher LSP laser energy and overlap applied, which showed a relative increase of surface compressive residual stress (CRS) and CRS depth by 54[Formula: see text] and 104[Formula: see text] respectively, compared to the conventional LSP treatment.
LTE trials in the return channel over satellite (2012)

Integrating terrestrial and satellite communications promises several advantages, whereas the most evident one is that modern satellite networks achieve global coverage using a multiple spot beam architecture. In order to increase the spectral efficiency, orthogonal waveforms like single-carrier frequency-division multiple access (SC-FDMA) are investigated recently. In this paper, we verify experimentally that SC-FDMA waveforms taken from the 3GPP Long Term Evolution (LTE) standard can be transmitted reliably in the return channel over satellite using low-cost equipment. Mainly, we introduce an additional timing advance offset depending on satellite elevation and geographical location. And we ensure that precise information about the frequency offset measured in the forward channel is reused for compensation in the return channel at each terminal. We demonstrate in real-time transmission experiments over a geostationary Ku-band satellite that all modulation formats defined for the up-link in the LTE Release 8 standard can be decoded error-free. Using 16-QAM, we have realized a spectral efficiency of 3.2 bits/s/Hz.
One‐pot Synthesis of Bulk NiMoS Catalysts: Influence of pH and Addition of Pluronic®P123. Hydrodesulfurization of Model Sulfur Molecules Representative of FCC Gasoline (2023)

Abstract The worldwide continual reinforcement of regulations for the production of cleaner fuels along with the larger demand for energy urge us to develop hydrotreatment sulfide catalysts exhibiting higher activity in hydrodesulfurization reactions and explore innovative synthesis strategies. In this work, a novel one‐pot synthesis method of unsupported NiMoS catalysts in water at ambient pressure and moderate temperature is described. The reaction conditions including pH variations and addition of a copolymer structuring agent were thoroughly investigated. Catalytic performances of the prepared bulk NiMoS catalysts were measured for the hydrodesulfurization of two model sulfur molecules, representative of FCC gasoline. Catalysts prepared at pH 7 without or with polymer exhibited roughly similar activity, resulting however from different characteristics favorable for catalyst efficiency probably compensating one another, i. e . a very high promotion rate for the first one and smaller particles along with larger specific surface area for the second.
An N-terminal Region of Mot-2 Binds to p53 In Vitro (2001)

The mouse mot-2 protein was earlier shown to bind to the tumor suppressor protein, p53. The mot-2 binding site of p53 was mapped to C-terminal amino acid residues 312-352, which includes the cytoplasmic sequestration domain. In the present study, we have found that both mot-1 and mot-2 bind to p53 in vitro. By using His-tagged deletion mutant proteins, the p53-binding domain of mot-2 was mapped to its N-terminal amino acid residues 253-282, which are identical in mot-1 and mot-2 proteins. Some peptides containing the p53-binding region of mot-2 were able to compete with the full-length protein for p53 binding. The data provided rationale for in vitro binding of mot-1 and mot-2 proteins to p53 and supported the conclusion that inability of mot-1 protein to bind p53 in vivo depends on secondary structure or its binding to other cellular factors. Most interestingly, the p53-binding region of mot-2 was common to its MKT-077, a cationic dye that exhibits antitumor activity, binding region. Therefore it is most likely that MKT-077-induced nuclear translocation and restoration of wild-type p53 function in transformed cells takes place by a competitional mechanism.
Genetically Defined Myelin Disorders (1992)

Myelin is a multilayered membranous sheath characteristic of nervous tissue. It insulates the axons of selected neurons along their entire length in discrete segments, increasing the conduction velocity of electrical nerve impulses traveling down these axons. The myelin is interrupted by bare patches of axon called nodes. Each myelinated segment is known as an internode. Myelin occurs in vertebrate nervous systems in two main forms, central and peripheral. It also occurs in some invertebrates in a form that resembles the myelin found in the peripheral nervous system (PNS) of vertebrates (Raine, 1984a).
Development and Evaluation of a Versatile Receptor-Ligand Binding Assay Using Cell Membrane Preparations Embedded in an Agarose Gel Matrix and Evaluation with the Human Adenosine A 1 Receptor (2020)

<i>Guanosine-5'-triphosphate (GTP)-binding protein-coupled receptors are the target of up to 40% of prescribed medications worldwide. To evaluate the suitability of novel receptor ligands, frequently elaborate, time-consuming, and expensive receptor-ligand interaction studies have to be carried out. This work describes the development and proof of principle of a rapid, sensitive, and reliable receptor-ligand binding assay. CHO cells were stably transfected with a construct encoding the human A<sub>1</sub> adenosine receptor (hA<sub>1</sub>AR). For ligand binding assays, membranes from these cells were prepared and embedded in low melting point agarose. These "immobilized" samples were incubated with tritiated 8-cyclopentyl-1,3-dipropylxanthine ([<sup>3</sup>H]DPCPX), a well-established receptor antagonist. The</i> K<i><sub>D</sub> and</i> B<i><sub>max</sub> values as well as kinetic parameters (</i>k<i><sub>on</sub> and</i> k<i><sub>off</sub>) of receptor-ligand interaction were determined. Unspecific binding of various radiotracers to either the carrier material or the agarose gel matrix was negligible. The dissociation constant (</i>K<i><sub>D</sub>) for [<sup>3</sup>H]DPCPX at the hA<sub>1</sub>AR was determined by saturation, competition binding, and kinetic experiments. These studies resulted in</i> K<i><sub>D</sub> values of ∼3 nM, which is in good accordance with previously published data obtained from conventional receptor-ligand binding assays. The procedure described in this study simplifies classical binding studies to a kit-like assay. The receptors retained their binding properties even when preparations were dried completely. Transport and delivery of the material are conceivable without loss of biological activity. Therefore, other laboratories can perform binding studies without special equipment or the necessity to run a cell culture laboratory and/or to dissect tissue on their own.</i>
Supplementary Table S5 from Cyst Fluid Telomerase Activity Predicts the Histologic Grade of Cystic Neoplasms of the Pancreas (2023)

&lt;p&gt;Supplementary Table S5;Diagnostic performance of telomerase activity in cases stratified by imaging features among discovery set cases&lt;/p&gt;
SAĞLIK HİZMETİ SUNUMUNDA VE SOSYAL PAZARLAMA KAPSAMINDA E-NABIZ UYGULAMASININ BİLİNİRLİĞİ (2017)

Sosyal pazarlama farkli hedef gruplarin tutum ve davranislarini degistirmeye odaklanir. Ayrica sosyal pazarlama, sosyal programin planlanmasi ve yonetimi icin pazarlama yaklasimlarinin uygulanmasini ortaya koyar. Sosyal pazarlama toplum sagligini gelistirme, kazalari onleme, cevreyi koruma ve benzeri uygulamalarda yaygin bir bicimde kullanilmaktadir. Gunumuzde insanlar bircok konu hakkinda bilgi sahibi olmak ve yasamini kolaylastiracak mal ve hizmetlerden haberdar olmak isterler. Bu istek ve ihtiyaclari konusunda sosyal pazarlama kampanyalari yoluyla bireylerin yeni bilgi ve uygulamalar hakkinda bilgi sahibi olmalari saglanir. Bu calismada, e-nabiz uygulamasi sosyal pazarlama kapsaminda degerlendirilmis ve Turkiye’de ki e-nabiz uygulamasinin bilinirligi olculmustur. Saglik hizmeti tuketicisi ve saglik calisanlarina anket yontemi uygulanmistir. Degerlendirmeye 273 anket alinmistir. Hem saglik tuketicileri hem de saglik calisanlari acisindan e-nabiz uygulamasinin orta ustu seviyede bilinirlige sahip oldugu ortaya cikmistir.
Polymeric Nanoparticle Preparation that Eradicates Tumors (2005)

We report the production of poly(lactic-co-glycolic acid) nanoparticles that encapsulate the photosensitizer meso-tetraphenylporpholactol. These nanoparticles are stable and nonphototoxic upon systemic administration. Upon cellular internalization, the photosensitizer is released from the nanoparticle and becomes highly phototoxic. Irradiation with visible light results in cell-specific killing of several cancer cell lines. Importantly, in vivo experiments show complete eradication of cancers in mouse models. The concept of photosensitizers with selective phototoxicity should have widespread applications in cancer therapy.
Ansa-metallocene and half-sandwich complexes of group-3 metals and lanthanides incorporating fluorenyl-based ligands: from synthesis to catalytic applications (2006)

This mini-review covers a series of neutral and ionic group-3 metal and lanthanide complexes bearing two different dianionic fluorenyl-based ligand systems, [Cp–CMe 2 –Flu] 2− and [Me 2 Si(3,6- t Bu 2 C 13 H 7 )(N t Bu)] 2− , which were synthesized upon using of diverse synthetic protocols. Structural aspects and bonding abilities of the fluorenyl ligand in these complexes are discussed, followed by some applications in polymerization and organic catalysis. .
[Relationship between soil bacterial community and environmental factors in the degraded alpine grassland of eastern Qilian Mountains, China]. (2018)

To explore the distribution of bacterial community and its relationship with soil environmental factors in degraded alpine grasslands in the eastern Qilian Mountains, we analyzed the changes of bacterial community structure and diversity across lightly, moderately and severely degraded grasslands by using high-throughput sequencing technology. Redundancy analysis (RDA) was performed to analyze the relationship between soil bacterial communities and soil environmental factors by using CANOCO 4.5 software. The results showed that there were significant differences in soil physicochemical properties among different degraded alpine grasslands. There were 257125 effective sequences, 180826 high-quality sequences and 4790 OTUs. The Chao1 index was lightly degraded grassland > moderately degraded grassland > severely degraded grassland; Shannon index was lightly degraded grassland > severely degraded grassland > moderately degraded grassland. Phylogenetic analysis indicated that the soil bacterial groups of each plot belonged to 33 phyla, with Actinomycetes, Proteobacteria and Firmicutes being the dominant groups in the three grasslands. From analysis of the proportion of soil bacteria in different degraded grassland, we found that the Actinomycetes, Acidobacteria and Proteobacteria increased first and then decreased with the degree of degradation, and the Firmicutes showed an opposite trend. The results of RDA analysis showed that the dominant groups of bacteria were significantly correlated with invertase, cellulase, phosphatas, pH, electronic conductivity, available nitrogen and available potassium. It was concluded that there were significant differences in soil bacterial communities among different degraded alpine grasslands in the eastern Qilian Mountains, and the soil environmental factors were the important factors driving the distribution of soil bacterial communities.