gebhart/patrepeval huggingface dataset:
ChemInform Abstract: Asymmetric Alkylation of Aromatic Aldehydes with Diethylzinc Catalyzed by a Fluorous BINOL—Ti Complex in an Organic and Fluorous Biphase System. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Organic polymeric thin-film transistors fabricated by selective dewetting (2002)

Thin-film transistors (TFTs) of polymeric semiconductors were fabricated using selective dewetting in the patterning process. The process consists of: (i) patterning the wettability of the substrate using a protective layer of printed wax and a self-assembled monolayer, and (ii) patterning a polymeric semiconductor by selective dewetting from an organic solution. The method has been used to fabricate small arrays of TFTs with a regioregular poly(thiophene) and poly(9-9′-dioctyl-fluorene-co-bithiophene). The TFTs exhibited mobilities of 0.5–1.0×10−3 cm2 V−1 s−1 and on-to-off ratios on the order of 104.
A short treatise concerning a musical approach for the interpretation of gene expression data (2015)

Recent technical developments allow the genome-wide and near-complete analysis of gene expression in a given sample, e.g. by usage of high-density DNA microarrays or next generation sequencing. The generated data structure is usually multi-dimensional and requires extensive processing not only for analysis but also for presentation of the results. Today, such data are usually presented graphically, e.g. in the form of heat maps. In the present paper, we propose an alternative form of analysis and presentation which is based on the transformation of gene expression data into sounds that are characterized by their frequency (pitch) and tone duration. Using DNA microarray data from a panel of neuroblastoma and Ewing sarcoma cell lines as well as from Hodgkin's lymphoma cell lines and normal B cells, we demonstrate that this Gene Expression Music Algorithm (GEMusicA) can be used for discrimination between samples with different biology and for the characterization of differentially expressed genes.
<title>Propagation of "exotic" laser beams in conditions of atmospheric turbulence and thermal blooming effects</title> (2004)

Analysis and numerical modeling of "exotic" laser beam propagation through inhomogeneous atmospheric media is performed. The exotic beam is synthesized by introducing an additional periodical dynamically changing phase modulation to a conventional outgoing beam base. The propagation media model includes a set of thin phase distorting layers corresponding to atmospheric turbulence-induced distortions and non-stationary nonlinear layers describing the thermal blooming effects that accompany high-energy laser beam propagation in a moving propagation medium. The exotic beam structure is optimized to have maximum energy inside the diffraction-limited size area on the target plane. Compared with propagation of conventional laser beams, the exotic beam exhibits better beam quality metrics on the target plane such as maximum intensity, centroid intensity, and energy in the vicinity of the maximum beam intensity and the centroid.
Energy efficient pricing scheme for multi-homing in heterogeneous wireless access networks: A game theoretic model and its analysis (2015)

For improving Quality of Service in wireless networks, multi-homing techniques have been considered as a promising solution. To date, most of the conventional research efforts have been focusing on user side interests (e.g. improving throughput, minimizing packet loss). However, a service provider could have different interests (e.g. profit, energy efficiency). Nevertheless, to the best of our knowledge, there is no research concern that takes into account the interests of user and service provider side at the same time. In this paper, we first model utility functions of both sides considering the aforementioned issues. Then, based on these utility functions we address the joint pricing and load distribution problem of multi-homing in heterogeneous wireless networks. Here, the problem is formulated into a Stackelberg game. Then, we propose schemes to obtain an optimal solution; so that, both sides (i.e. service providers and users) are satisfied. Finally, we provide rigorous analysis varying different parameters (e.g. cost, rate allocation, energy efficiency) which can potentially affect to the game. In addition to that, we show the proposed schemes are well converged to equilibrium point.
Improving the Li-Electrochemical Properties of Monodisperse Ni2P Nanoparticles by Self-Generated Carbon Coating (2012)

Carbon coating of electrode materials is nowadays a major tool to improve the electronic percolation of the electrode. In this study, a self-generated carbon coating is described as a new way to deposit a regular thin layer of carbon on the surface of nanoparticles. It relies on the soft decomposition of the nanoparticles surface native ligands, containing alkyl chains, under inert atmosphere at 400 °C, a route particularly suited for oxidation-sensitive nanoparticles. Using 25 nm monodispersed Ni2P nanoparticles as a model phase, we succeeded in forming nonsintered and nonoxidized carbon-coated nanoparticles. The carbon coating is then tuned in thickness by modifying the ligands set. Electrochemical properties of the resulting Ni2P/C nanoparticles vs Li are compared with those of bulk Ni2P. Both materials are shown to undergo a conversion reaction. The capacity of the bulk material collapses after a few cycles while Ni2P/C nanoparticles show much better retention. The self-generated carbon coating is thus found to promote Li uptake by providing a Li-permeable electron-conductive percolating network and by improving the mechanical integrity of the electrode.
Integrated single-nucleotide and structural variation signatures of DNA-repair deficient human cancers (2018)

Mutation signatures in cancer genomes reflect endogenous and exogenous mutational processes, offering insights into tumour etiology, features for prognostic and biologic stratification and vulnerabilities to be exploited therapeutically. We present a novel machine learning formalism for improved signature inference, based on multi-modal correlated topic models (MMCTM) which can at once infer signatures from both single nucleotide and structural variation counts derived from cancer genome sequencing data. We exemplify the utility of our approach on two hormone driven, DNA repair deficient cancers: breast and ovary (n=755 cases total). Our results illuminate a new age-associated structural variation signature in breast cancer, and an independently identified substructure within homologous recombination deficient (HRD) tumours in breast and ovarian cancer. Together, our study emphasizes the importance of integrating multiple mutation modes for signature discovery and patient stratification, with biological and clinical implications for DNA repair deficient cancers.
Biological and biochemical characterization of tunicamycin-resistant Leishmania mexicana: mechanism of drug resistance and virulence (1987)

A parasitic protozoan, Leishmania mexicana amazonensis, was previously made resistant to tunicamycin (J.A. Kink and K.-P. Chang, Proc. Natl. Acad. Sci. USA 84:1253-1257, 1987). In the present study, six different tunicamycin-resistant variants were biologically and biochemically compared with their parental wild type to further delineate the mechanism of tunicamycin resistance and that of their virulence observed. In contrast to their parental wild type, all tunicamycin-resistant variants were found to grow and differentiate in tunicamycin-containing medium. The 50% lethal doses of tunicamycin for variants resistant to 10 or 80 micrograms of tunicamycin per ml were 20- and 100-fold higher, respectively, than that of the wild type. Specific activity of the microsomal N-acetylglucosamine-1-phosphate transferase was 4- to 12-fold higher in the tunicamycin-resistant cells than in their parental wild type and tunicamycin-sensitive revertants. The level of the enzyme activity is proportional to the degree of drug resistance. Inhibition kinetics studies showed that the enzyme from all groups was equally sensitive to the drug, with a 50% effective concentration of 1 to 1.3 micrograms of tunicamycin per ml. Thus, tunicamycin resistance of the variants is caused primarily by an increased level of their enzyme without alteration of its structure. Protein glycosylation determined by the incorporation of 2-D-[3H]mannose was about twofold higher in the tunicamycin-resistant variants than in their parental wild type. The increased glycosyltransferase activity in the latter apparently renders their protein glycosylation insensitive to the inhibition by tunicamycin. A major membrane glycoprotein of 63 kilodaltons (gp63) on the leishmania surface was found to be about threefold higher in the tunicamycin-resistant variants than in the wild type, as determined by immunoprecipitation with a monoclonal antibody specific for this antigen. Tunicamycin treatment of the wild type and tunicamycin-resistant variants caused changes in the electrophoretic mobility of this molecule, indicating a higher degree of its glycosylation in the latter cells. The tunicamycin-resistant variants parasitized macrophages in vitro more effectively than did the wild type, accounting for their virulence seen in mice. Thus, a high level of the glycosyltransferase enables the tunicamycin-resistant cells not only to overcome the inhibitory effect of tunicamycin on protein glycosylation but also to express their virulence, possibly by regulating N glycosylation of leishmanial proteins critical for leishmanias to establish intracellular parasitism.
Acoustic variability and distinguishability among mouse ultrasound vocalizations (2003)

Auditory neurobiology has benefited significantly from ethological approaches using acoustic communication signals. Developing an ethological model in a genetically manipulable system such as the mouse would enhance the ability to investigate the processing, learning, and recognition of sounds. Characterizing the basic acoustic structure of mouse vocalizations would help lay a foundation for such a future study. Towards this goal, ultrasound vocalizations emitted by isolated mouse pups and pairs of adult males and females have been digitally recorded and examined. Previous work suggests that these calls may have communicative significance. An analysis of the natural variability in their spectral content, median frequency, duration, and repetition period reveals acoustic structure that could be used for recognizing the calls. Other parameters, like the rate of frequency modulation, may also be informative, but have not been examined. Pup isolation calls develop systematically between postnatal day 5 and 12 towards a more stereotyped vocalization--contracting from a wide range of values into narrower clusters of frequency and duration, and shifting from longer to shorter repetition periods. Most significantly, pup isolation and adult encounter calls fall into two distinct spectral and temporal categories, making it possible for a receiver to acoustically distinguish between them, and to potentially categorically perceive them along those dimensions.
Improved quantification of small objects in near-infrared diffuse optical tomography (2004)

Diffuse optical tomography allows quantification of hemoglobin, oxygen saturation, and water in tissue, and the fidelity in this quantification is dependent on the accuracy of optical properties determined during image reconstruction. In this study, a three-step algorithm is proposed and validated that uses the standard Newton minimization with Levenberg-Marquardt regularization as the first step. The second step is a modification to the existing algorithm using a two-parameter regularization to allow lower damping in a region of interest as compared to background. This second stage allows the recovery of the actual size of an inclusion. A region-based reconstruction is the final third step, which uses the estimated size and position information from step 2 to yield quantitatively accurate average values for the optical parameters. The algorithm is tested on simulated and experimental data and is found to be insensitive to object contrast and position. The percentage error between the true and the average recovered value for the absorption coefficient in test images is reduced from 47 to 27% for a 10-mm inclusion, from 38 to 13% for a 15-mm anomaly, and from 28 to 5.5% for a 20-mm heterogeneity. Simulated data with absorbing and scattering heterogeneities of 15 mm diam located in different positions show recovery with less than 15% error in absorption and 6% error in reduced scattering coefficients. The algorithm is successfully applied to clinical data from a subject with a breast abnormality to yield quantitatively increased absorption coefficients, which enhances the contrast to 3.8 compared to 1.23 previously.
Synergy of Miniemulsion and Solvothermal Conditions for the Low-Temperature Crystallization of Magnetic Nanostructured Transition-Metal Ferrites (2016)

Crystalline first-row transition-metal (Mn, Fe, Co, Ni, Cu, and Zn) ferrites were prepared by an unprecedented synergetic combination of miniemulsion synthesis and solvothermal route, pursuing unconventional conditions in terms of space confinement, temperature, and pressure. This synergy allowed for obtaining six different crystalline ferrites at much lower temperature (i.e., 80 °C) than usually required and without any postsynthesis thermal treatment. X-ray diffraction (XRD) revealed that analogous ferrites synthesized by miniemulsion at ambient pressure or in bulk (i.e., from an aqueous bulk solution and not in the confined space of the miniemulsion droplets) either at ambient pressure or under solvothermal conditions did not result in comparatively highly crystalline products. To follow the structural evolution at local level as a function of reaction time and depending on the synthesis conditions, X-ray absorption spectroscopy (XAS) was used to determine the cation distribution in these structures. Well-defined nanostructures were observed by transmission electron microscopy (TEM). Concerning their functional behavior, the synthesized ferrites presented superparamagnetism and were found to be active oxidation catalysts, as demonstrated for the oxidation of styrene, taken as a model reaction. Because of the magnetic properties, the ferrites can be easily recovered from the reaction medium, after the catalysis, by magnetic separation and reused for several cycles without losing activity.
Occurrence of the Root-Knot Nematodes Meloidogyne incognita and M. hapla in Slovenia (2003)

The root-knot nematode Meloidogyne incognita (Kofoid & White) Chitwood is one of the most harmful species within the genus Meloidogyne. It has been detected regularly in greenhouses throughout Europe, while in the field it is restricted to the southern parts of Europe (4). M. incognita is able to parasitize more than 700 plant species and varieties, including the majority of our economically important crops (1). It has been recorded in most parts of the world, including former Yugoslavia; however, there is no data about its presence in Slovenia. In late summer of 2002, large galls were observed on roots of pepper, Capsicum annuum L., grown in a greenhouse located in Portorož near the Adriatic Coast of Slovenia. Different root-knot nematode stages, i.e., males, females, and second-stage juveniles, were isolated and morphologically identified as M. incognita (2). Additional isozyme gel electrophoresis confirmed this (3). To our knowledge, this is the first report of M. incognita from Slovenia. In addition, M. hapla Chitwood was found for the first time in a field in Slovenia. Previously, it had been detected on different host plants, all restricted to greenhouses. In October 2002, M. hapla was isolated and identified from relatively small galls of sweet pepper, C. annuum L., grown in a field near Ljubljana, located in central Slovenia. Additional resampling of the soil comfirmed the presence of M. hapla in this field. References: (1) J. D. Eisenback. Root-Knot Nematode Taxonomic Database. CD-ROM, CABI, Wallingford, UK, 1998. (2) J. D. Eisenback and H. Hirschmann Triantaphyllou. Root-knot nematodes: Meloidogyne species and races. Pages 191-274 in: Manual of Agricultural Nematology. W. R. Nickle, ed. Marcel Dekkers, Inc., New York, 1991. (3) P. R. Esbenshade and A. C. Triantaphyllou. J. Nematol. 17:6, 1985. (4) G. Karssen. Revision of the European root-knot nematodes III on mono- and dicotyledons. Pages 119-121 in: The Plant-Parasitic Nematode Genus Meloidogyne Göldi, 1892 (Tylenchida) in Europe. Koninklijke Brill NV, Leiden, the Netherlands, 2002.
Optimum subband coding of cyclostationary signals (1999)

We consider the optimal orthonormal subband coding of zero mean cyclostationary signals, with N-periodic second order statistics. A 2-channel uniform filter bank, with N-periodic analysis and synthesis filters, is used as the subband coder. A dynamic scheme involving N-periodic bit allocation is employed. An average variance condition is used to measure the output distortion. The conditions for maximizing the coding gain parallel those for the case when the signals are wide sense stationary (WSS) and the analysis and synthesis filters and the bit allocation time invariant, in that the blocked subband signals must be decorrelated and the subband power spectral densities must obey an ordering. Some additional conditions on this ordering, over and above those required for the WSS case, are needed.
The photoreversible oxidative-addition, reductive-elimination reactions iron + molecular hydrogen .dblharw. iron hydride (FeH2) in low-temperature matrixes (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe photoreversible oxidative-addition, reductive-elimination reactions iron + molecular hydrogen .dblharw. iron hydride (FeH2) in low-temperature matrixesGeoffrey A. Ozin and John G. McCaffreyCite this: J. Phys. Chem. 1984, 88, 4, 645–648Publication Date (Print):February 1, 1984Publication History Published online1 May 2002Published inissue 1 February 1984https://pubs.acs.org/doi/10.1021/j150648a002https://doi.org/10.1021/j150648a002research-articleACS PublicationsRequest reuse permissionsArticle Views184Altmetric-Citations43LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
High-Throughput Semi-Honest Secure Three-Party Computation with an Honest Majority (2016)

In this paper, we describe a new information-theoretic protocol (and a computationally-secure variant) for secure three-party computation with an honest majority. The protocol has very minimal computation and communication; for Boolean circuits, each party sends only a single bit for every AND gate (and nothing is sent for XOR gates). Our protocol is (simulation-based) secure in the presence of semi-honest adversaries, and achieves privacy in the client/server model in the presence of malicious adversaries. On a cluster of three 20-core servers with a 10Gbps connection, the implementation of our protocol carries out over 1.3 million AES computations per second, which involves processing over 7 billion gates per second. In addition, we developed a Kerberos extension that replaces the ticket-granting-ticket encryption on the Key Distribution Center (KDC) in MIT-Kerberos with our protocol, using keys/ passwords that are shared between the servers. This enables the use of Kerberos while protecting passwords. Our implementation is able to support a login storm of over 35,000 logins per second, which suffices even for very large organizations. Our work demonstrates that high-throughput secure computation is possible on standard hardware.
Supplementary File 2_Gene Sets from Pathway-Enriched Gene Signature Associated with 53BP1 Response to PARP Inhibition in Triple-Negative Breast Cancer (2023)

&lt;p&gt;Literature derived gene sets from which curated gene set list created.&lt;/p&gt;
Comparison of Cytotoxicity of Mononucleoside Phosphotriester Derivatives Bearing Biolabile Phosphate Protecting Groups in Normal Human Bone Marrow Progenitor Cells (1996)

The effects of three mononucleoside phosphotriester derivatives of 3′-azido-2′,3′-dideoxythymidine (AZT) which incorporate biolabile phosphate protecting groups, namely S-acetyl-2-thioethyl (MeSATE), S-(2-hydroxyethylsulfidyl)-2-thioethyl (DTE), and pivaloyloxymethyl (POM) were studied and compared to their nucleoside parent in human myeloid colony-forming cells. Moreover, the relative antiviral potency of these three pronucleotides were determined in primary human peripheral blood mononuclear cells infected with human immunodeficiency virus type 1. The results indicate that the SATE and DTE pro-moieties, as well as their degradation products, do not induce additional toxicity. The bis(MeSATE) phosphotriester derivative of AZT emerged as the most selective inhibitor with an in-vitro therapeutic index of the same order of magnitude as observed for AZT. This study has been extended to the corresponding bis(MeSATE) and bis(DTE) phosphotriester derivatives of 2′,3′-dideoxyuridine (ddU).
Nanotechnology inspired biosensor with photo-responsive liquid crystals (2021)

We aim to realize a novel nanotechnology-based biosensor specifically utilized to detect harmful bacteria in potable water. The nano-inspired device makes use of a chemically functionalized gold nanorods array (for the selective selection of specific pathogens) layered with a photo-responsive nematic liquid crystal (NLC) film for real-time and high sensitivity detection. The first experimental results are presented and discussed.
Development of modulation strategies for NPC converter addressing DC link voltage balancing and CMV reduction (2012)

3L-NPC inverters are more popular due to their superior performance compared with two level inverters. One of the most optimal applications for multilevel inverter is the Adjustable Speed Drives (ASD). The industry reported numerous ASD failures due to high frequency PWM. Those failures consist in insulation breakdown and bearing failures. By the use of this type of converters, both Electromagnetic Interference (EMI) and harmonic distortions are improved. This paper proposes two modulation strategies for Three Level Neutral Point Clamped Converter (3L-NPC). The main focus of these modulation strategies is to reduce the Common Mode Voltage (CMV) and balance the DC Link Voltage.