gebhart/patrepeval huggingface dataset:
Sub-wavelength imaging from multilayer superlens (2010)

Multilayer superlens has been reported that it had advantages over the original single slab superlens [1]. In this work, single silver layer and Ag-SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> multilayer superlens devices working at wavelength of 365 nm were fabricated using standard photolithography method. Grating object with sub-wavelength resolution could be resolved through both kinds of superlens with working distance up to 128 nm. However, Ag-SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> multilayer superlens shows higher transmittance and image contrasts than the single silver layer one, this result verifies the theoretical results in Ref. [1].
Iatrogenic Tracheal Rupture: A Novel Approach to Repair and a Review of the Literature (2003)

Satyadas, T. BSc, MD, FRCS; Nasir, N. MD; Erel, E. MD; Mudan, Satvinder S. MD Author Information
Chain polymerizations in inert near- and supercritical fluids (1995)

This article summarizes the chain polymerizations that have been conducted in near- and supercritical reaction media, with primary emphasis on polymerizations that have been conducted in CO 2 in our laboratories. In all of the polymerizations that will be discussed, the near- and supercritical fluid served only as the reaction medium and was effectively inert to the chemistry conducted
Copy-number variants in patients with a strong family history of pancreatic cancer (2007)

Copy-number variants such as germ-line deletions and amplifications are associated with inherited genetic disorders including familial cancer. The gene or genes responsible for the majority of familial clustering of pancreatic cancer have not been identified. We used representational oligonucleotide microarray analysis (ROMA) to characterize germ-line copy number variants in 60 cancer patients from 57 familial pancreatic cancer kindreds. Fifty-seven of the 60 patients had pancreatic cancer and three had nonpancreatic cancers (breast, ovary, ovary). A familial pancreatic cancer kindred was defined as a kindred in which at least two first-degree relatives have been diagnosed with pancreatic cancer. Copy-number variants identified in 607 individuals without pancreatic cancer were excluded from further analysis. A total of 56 unique genomic regions with copy-number variants not present in controls were identified, including 31 amplifications and 25 deletions. Two deleted regions were observed in two different patients, and one in three patients. The germ-line amplifications had a mean size of 662 Kb, a median size of 379 Kb (range 8.2 Kb to 2.5 Mb) and included 425 known genes. Examples of genes included in the germ-line amplifications include the MAFK, JunD and BIRC6 genes. The germ-line deletions had a mean size of 375Kb, a median size 151 Kb (range 0.4 Kb to 2.3 Mb) and included 81 known genes. In multivariate analysis controlling for region size, deletions were 90% less likely to involve a gene than were duplications (p < 0.01). Examples of genes included in the germ-line deletions include the FHIT, PDZRN3 and ANKRD3 genes. Selected deletions and amplifications were confirmed using real-time PCR, including a germ-line amplification on chromosome 19. These genetic copy-number variants define potential candidate loci for the familial pancreatic cancer gene.
Microseismic network design for dedicated geologic storage of carbon in the Los Angeles Basin (2022)

Network modeling for Carbon Capture and Storage (CCS) can be us ed to determine the optimal placement of microseismic networks to monitor CO2 plume evolution. This study uses a demonstrational data set from the Los Angeles basin to perform network modeling based on dynamic simulation of a 20-million-ton CO2 injection scenario. The objective of network design is to meet specific detectability targets bas ed on induced seismicity, caprock leakage, and hidden feature risks.
Divide-and-conquer techniques for global throughput optimization (2002)

The paper proposes a divide-and-conquer approach for global throughput optimization designed to coordinate existing techniques and enable their more effective use. The "divide" approach consists of logical partitioning of the computation into subparts. The techniques for partitioning the computation, and the corresponding scheme for classifying the subparts is presented. The subparts are optimized or "conquered" through coordinated application of existing optimization techniques. Optimization techniques that are effective for each class have been characterized in terms of their expected effect on throughput. The approach is not limited to a specific class of computations and gives higher, or at least equal, improvement than previously reported techniques on all examples.
Different mechanisms decrease hepatic collagen and albumin production in fasted rats (1988)

Weight loss is correlated with a specific decrease in collagen synthesis in extrahepatic tissues, mainly through modulation of mRNA levels. Here, we investigated the response to weight loss in the rat liver. Male rats were either fed ad libitum or fasted for 92 hr; fasted animals lost approximately 20% of their initial body weight. Following i.p. injection of [5-3H]proline, hepatic collagen was extracted and de novo collagen production was measured. There was a decrease in the specific radioactivities of purified hepatic collagen (-75%) and albumin (-70%) relative to total hepatic protein, indicating that production of both of these proteins was specifically decreased. In fasted animals, the absolute hepatic collagen production was markedly decreased (-60%), while changes in absolute hepatic protein production were small (-15%). Using hybridization with specific DNA probes, we found that fasting causes about a 70% decrease in albumin mRNA, but the quantities of hepatic procollagen alpha 1(I) and alpha 2(I) mRNAs were unchanged. These results are consistent with regulation of albumin production during fasting by modulation of mRNA levels. The inhibition of hepatic collagen production in fasted animals, however, appears to be modulated at a posttranscriptional level or may result from increased degradation. This response differs from the pretranslational regulation of collagen synthesis in extrahepatic tissues during fasting. Furthermore, our results suggest that decreased body weight could be a potentially complicating variable in studies of collagen metabolism and fibrogenesis in the liver.
Ectopic pregnancy risk factors in infertile patients: a 10-year single center experience (2022)

Abstract The present retrospective study included both in vivo and in vitro assisted reproductive technologies (ART) procedures performed from January 2009 to December 2018 at a tertiary-care Fertility Centre. The purpose was to assess the incidence of ectopic pregnancy (EP) in infertile population who undergoes ART and to identify any risk factor impacting the occurrence of EP after ART. Among 27,389 cycles, 7,352 pregnancies were achieved, of which 132 were EPs, the 1.80% (95% CI 1.5-2.1) of all pregnancies. In fresh cycles, a history of prior pelvic adhesions showed the greatest impact on the incidence of EP (aOR 2.49 95% CI 1.53 – 4.07 p &lt; 0.001). Other factors associated with EP incidence were also identified, such as female age, basal FSH, the transfer of blastocyst embryos and difficulties during the embryo transfer procedure. In frozen cycles, the only factor influencing the incidence of EP was Anti-Mullerian Hormone (AMH) serum concentration (aOR 0.81 95% CI 0.65 – 1.00, p = 0.048). To conclude, the incidence of EP observed was comparable to that reported after natural conception. On the other hand, pre-existing risk factors, traditionally more common in infertile population, appeared to influence the incidence of EP and should thus be modified if possible.
Improved space-time trellis codes for correlated MIMO channels (2005)

Space-time code designs commonly rely on the assumption of independent and identically distributed (i.i.d.) Rayleigh channels. However, poor scattering conditions can have detrimental effects on the performance of space-time codes. We derive new space-time trellis codes that are robust in the presence of a large variety of propagation conditions. First, robust space-time trellis codes are derived when the transmitter has no channel knowledge. Then, trellis codes exploiting some statistical knowledge of the channel at the transmitter are presented. Codes satisfying these criteria are shown to perform much better in real-world channels than codes designed only for i.i.d. channels.
A multiport vector network analyzer with high-precision and realtime capabilities for brain imaging and stroke detection (2018)

Abstract Medical imaging is of great importance for patients affected by stroke. Since an early examination of the patient is necessary for successful recovery, there is room to improve the existing capabilities of analysis. Common systems like magnetic resonance imaging or computed tomography are precise, but stationary, and therefore, not ideally suited for the early analysis of stroke. The presented multiport vector network analyzer system uses electromagnetic tomography (EMT) as an alternative imaging technique. It consists of a network of distributed electronic sensor nodes which improve important parameters: the parallel measurement setup reduces the measurement time as low as 160 ms for a 200-port S-parameter matrix and it is capable of measuring signal levels down to − 150 dBm. The electronics allow a compact, movable packaging, leading the way for future portable devices. The detection of stroke models was examined by test measurements of a phantom. The data was analyzed by the help of an inverse reconstruction algorithm. The possibility of building portable setups which can be even applied to patients inside an ambulance, makes EMT a suitable alternative for early stroke detection. It can help in shortening the recovery of patients, by providing an early analysis of the brain.
A genetic solution for the traveling salesman problem by means of a thermodynamical selection rule (2002)

For successful applications of the genetic algorithm, there are two important points to be considered. The first point is the design of the fitness landscape introduced by the representation of the solution as a gene and searching operations such as crossover and mutation. The second is control of the convergence brought about by the selection operation. In the conventional implementation of GA, these two points are mutually dependent, i.e., a suitable selection pressure varies largely depending on, e.g., the crossover operator. Hence, it requires much trial-and-error effort to find a nice configuration of GA. The authors apply a novel selection rule, the Thermodynamical Genetic Algorithm (TDGA) proposed by N. Mori et al. (1995) to the traveling salesman problem (TSP), and propose an adaptive annealing schedule of the temperature in TDGA. Computer simulation with several crossover operators for TSP shows that TDGA reduces the mutual dependency between the fitness landscape and the convergence process.
Interfacial Organization in Dipolar Dye-Based Organic Nanoparticles Probed by Second-Harmonic Scattering (2015)

We have undertaken polarization-resolved SHS experiments to investigate a series of two fluorescent organic nanoparticles (FONs) made from dipolar dyes bearing a triphenylamine-donating end-group and a slightly hydrophilic acceptor end-group. The FONs, which show very large negative surface potentials, responsible for their good colloidal stability in water, are very bright SHS emitters in water, attractive for single-particle tracking and bioimaging. With the polarization-resolved SHS technique, we come up with a new and noninvasive method to gain insight into the origin of the surface potential of the FONs, as well as into their evolution upon change of ionic strength by following their multipolar response when adding salt. In pure water, the polarization-resolved SHS spectroscopy reveals the presence of a region of local polar order close to the surface (i.e., orientation of the dipolar dyes), leading to a strong dipolar contribution. Quite interestingly, when adding KCl salt, the initial two-lobe SHS polar plot transforms into a four-lobe pattern with a net decrease of the SHS intensity, revealing a lower surface potential. Second, we have quantified the decrease of the SHS signal when adding salt with the goal to estimate the change of the NPs’ colloidal stability in salty media. From a simple equilibrium model that we propose, we have extracted a lower bound free energy for the two FONs, which are thermally accessible and in good accordance with their respective colloidal stability.
Handbuch Bauelemente der Optik (2020)

You have accessHandbuch Bauelemente der OptikJan 2020Handbuch Bauelemente der OptikGrundlagen, Werkstoffe, Geräte, MesstechnikMartin Löffler-Mang, Helmut Naumann, Gottfried SchröderMartin Löffler-Mang, Helmut Naumann, Gottfried Schröderhttps://doi.org/10.3139/9783446461260.fmSectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF key 'share (en)' returned an object instead of string.FacebookTwitterEmailLinkedIn next chapter FiguresReferencesRelatedDetails 2020Pages: I-XXIIIPrint ISBN: 978-3-446-46032-4eISBN: 978-3-446-46126-0 Copyright & Permissions© 2020 Carl Hanser Verlag GmbH & Co. KGPDF downloadLoading ...
Discovery of protein acetylation patterns by deconvolution of peptide isomer mass spectra (2015)

Protein post-translational modifications (PTMs) play important roles in the control of various biological processes including protein-protein interactions, epigenetics and cell cycle regulation. Mass spectrometry-based proteomics approaches enable comprehensive identification and quantitation of numerous types of PTMs. However, the analysis of PTMs is complicated by the presence of indistinguishable co-eluting isomeric peptides that result in composite spectra with overlapping features that prevent the identification of individual components. In this study, we present Iso-PeptidAce, a novel software tool that enables deconvolution of composite MS/MS spectra of isomeric peptides based on features associated with their characteristic fragment ion patterns. We benchmark Iso-PeptidAce using dilution series prepared from mixtures of known amounts of synthetic acetylated isomers. We also demonstrate its applicability to different biological problems such as the identification of site-specific acetylation patterns in histones bound to chromatin assembly factor-1 and profiling of histone acetylation in cells treated with different classes of HDAC inhibitors.
Studies toward an enantioselective total synthesis of (-)- aleurodiscal / (1996)

NMR of compound 34 in CDCI3 20 NMR of compound 36 in CDCI3 21 iR NMR of compound 37 in CDCI3 .22 "h NMR of compound 39 in CDCI3 .23 "h NMR of compound 40 in CDCI3 .24 NMR of compound 41 in CsDe-25 1H NMR of compound 43 in CDCI3 , 26 NMR of compound 45 in CDCI3 , 27 1 H NMR of compound 46 in CDCI3 28 NMR of compound 47 in CDCI3 .29 1 H NMR of compound 48 in CDCI3 .30 1 H NMR of compound 49 in CDCI3 .31 '' H NMR of compound 51 in CDCI3 .32 ^ H NMR of compound 52 in CDCI3 .33 H NMR of compound 53 in CDCI3 .34 NMR of compound 54 in CDCI3 , 35 ' ' H NMR of compound 55 in CDCI3 .36 1 H NMR of compound 56 in CDCI3 .37 NMR of compound 58 in CDCI3 .38 1H NMR of compound 59 in CDCI3 .3 9 NMR of compound 59a,b in CDCI3 ...........
Stereochemistry of the permanganate oxidation of 1,5-dienes (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereochemistry of the permanganate oxidation of 1,5-dienesD. M. Walba, M. D. Wand, and M. C. WilkesCite this: J. Am. Chem. Soc. 1979, 101, 15, 4396–4397Publication Date (Print):July 1, 1979Publication History Published online1 May 2002Published inissue 1 July 1979https://doi.org/10.1021/ja00509a069Request reuse permissionsArticle Views273Altmetric-Citations76LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (294 KB) Get e-Alertsclose Get e-Alerts
Pharmacological inhibition of the transcription factor PU.1 in leukemia (2017)

The transcription factor PU.1 is often impaired in patients with acute myeloid leukemia (AML). Here, we used AML cells that already had low PU.1 levels and further inhibited PU.1 using either RNA interference or, to our knowledge, first-in-class small-molecule inhibitors of PU.1 that we developed specifically to allosterically interfere with PU.1-chromatin binding through interaction with the DNA minor groove that flanks PU.1-binding motifs. These small molecules of the heterocyclic diamidine family disrupted the interaction of PU.1 with target gene promoters and led to downregulation of canonical PU.1 transcriptional targets. shRNA or small-molecule inhibition of PU.1 in AML cells from either PU.1lo mutant mice or human patients with AML-inhibited cell growth and clonogenicity and induced apoptosis. In murine and human AML (xeno)transplantation models, treatment with our PU.1 inhibitors decreased tumor burden and resulted in increased survival. Thus, our study provides proof of concept that PU.1 inhibition has potential as a therapeutic strategy for the treatment of AML and for the development of small-molecule inhibitors of PU.1.
1 Einleitung (2011)

Dieser Band ist ein Überblickswerk der Schulsportforschung. Dargestellt werden zentrale Untersuchungsansätze, Forschungsergebnisse und Forschungsperspektiven für den Schulsport. Die Befunde sind in vier Forschungsfelder "Unterrichtsforschung", "Schülerforschung", "Lehrerforschung" und "Schulsportentwicklungsforschung" differenziert und thematisch entfaltet. Zu jedem Forschungsfeld gibt es einen umfangreichen und grundlegenden Basistext und jeweils einen oder zwei ergänzende Beiträge z. B. zu Heterogenität und Koedukation, motorischer Leistungsfähigkeit und Evaluation, Lehrplanarbeit und Ganztag.
Coding scheme for low energy consumption fault-tolerant bus (2003)

We address the problem of devising the error correcting code which, if used to encode the information on a very deep submicron (VDSM) bus, allows us to achieve fault-tolerance with the minimal impact on bus power consumption and power-delay product. In particular, we first report the results of an analysis that we performed on power dissipation in VDSM fault-tolerant busses using Hamming single error correcting codes. We show that no power saving is possible by choosing between different optimal Hamming codes with the same redundancy. We then propose a new coding scheme which provides a reduction of the energy consumption and power-delay product of over the 11.5% and 45%, respectively, with respect to the optimal (7,4) Hamming code, for a 0.13/spl mu/m CMOS technology bus.
ChemInform Abstract: Studies on DNA‐Cleaving Agents: Synthesis of a Functional Dynemicin Analogue. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Traveling‐Wave Tubes (2005)

Abstract The traveling‐wave tube (TWT) is a vacuum device invented in the early 1940s [1,2] used for amplification at microwave frequencies. Amplification is attained by surrendering kinetic energy from an electron beam to a radiofrequency (RF) electromagnetic wave. The demand for vacuum devices has been decreasing largely owing to the advent of solid‐state devices. However, although solid state devices have replaced vacuum devices in many areas, there are still many applications such as radar, electronic countermeasures, and satellite communications that require operating characteristics such as high power (watts to megawatts), high frequency (below 1GHz to over 100 GHz), high efficiency (65% efficient, 100 Watt, Kaband TWTs are commonplace), and large bandwidth that only vacuum devices can provide. The term traveling‐wave tube includes both fast‐wave and slow‐wave devices. This article will concentrate on slow‐wave devices as the vast majority of TWTs in operation around the world fall into thiscategory.
Staphylococcus aureus‐induced complement activation promotes tissue factor‐mediated coagulation (2018)

Background There is extensive cross-talk between the complement system, the Toll-like receptors (TLRs), and hemostasis. Consumptive coagulopathy is a hallmark of sepsis, and is often mediated through increased tissue factor (TF) expression. Objectives To study the relative roles of complement, TLRs and TF in Staphylococcus aureus-induced coagulation. Methods Lepirudin-anticoagulated human whole blood was incubated with the three S. aureus strains Cowan, Wood, and Newman. C3 was inhibited with compstatin, C5 with eculizumab, C5a receptor 1 (C5aR1) and activated factor XII with peptide inhibitors, CD14, TLR2 and TF with neutralizing antibodies, and TLR4 with eritoran. Complement activation was measured by ELISA. Coagulation was measured according to prothrombin fragment 1 + 2 (PTF<sub>1 + 2</sub> ) determined with ELISA, and TF mRNA, monocyte surface expression and functional activity were measured with quantitative PCR, flow cytometry, and ELISA, respectively. Results All three strains generated substantial and statistically significant amounts of C5a, terminal complement complex, PTF<sub>1 + 2</sub> , and TF mRNA, and showed substantial TF surface expression on monocytes and TF functional activity. Inhibition of C5 cleavage most efficiently and significantly inhibited all six markers in strains Cowan and Wood, and five markers in Newman. The effect of complement inhibition was shown to be completely dependent on C5aR1. The C5 blocking effect was equally potentiated when combined with blocking of CD14 or TLR2, but not TLR4. TF blocking significantly reduced PTF<sub>1 + 2</sub> levels to baseline levels. Conclusions S. aureus-induced coagulation in human whole blood was mainly attributable to C5a-induced mRNA upregulation, monocyte TF expression, and plasma TF activity, thus underscoring complement as a key player in S. aureus-induced coagulation.
Effects of Frequent Hemodialysis on Ventricular Volumes and Left Ventricular Remodeling (2013)

Frequent in-center hemodialysis reduces left and right ventricular end systolic and diastolic ventricular volumes as well as left ventricular mass, but it does not affect left ventricular remodeling.