gebhart/patrepeval huggingface dataset:
An ASIC architecture for contour line filtering (2003)

Proposes an application-specific IC architecture for implementing a contour line filter for a real-time fingerprint recognition system. The architecture demonstrates the fact that a library-based set of data-path modules which are steered by powerful, synchronized controllers can result in real-time performance on a single chip, even for a complex image processing application. Moreover, the external frame memories required are minimized in the design by working in-place and by appropriate scheduling at the cost of little extra hardware and few additional evaluation cycles.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Antibody targeting of endothelial Tie1 receptor as an anti-angiogenic sensitizer in tumor therapy (2008)

2492 Tie1, an endothelial cell-specific receptor tyrosine kinase, is essential for the development of the vascular system. Targeted disruption of the Tie1 gene results in mouse embryonic lethality after mid-gestation due to severe edema, extensive hemorrhage and defective microvessel integrity. Tie1 expression is upregulated during wound healing, ovarian follicle maturation and tumor angiogenesis. Members of the angiopoietin ligand family that activate the related Tie2 receptor stimulate also Tie1 phosphorylation. We have here analyzed the effect of Tie1-targeted antibodies on human tumor growth in mouse xenograft models as a monotherapy and in combination with clinically approved anti-angiogenic agents. Our results show that antibody targeting Tie1 inhibits tumor growth. Immunohistochemical analysis indicated that anti-Tie1 treated tumors displayed a distinct vascular pattern with abnormal vessel sprouting, detachment of smooth muscle cells and increased hypoxia and necrosis. This vessel destabilization sensitizes tumor vasculature to other anti-angiogenic agents leading to improved efficacy. As the most effective inhibition of tumor progression may require inhibition of multiple angiogenic pathways, antibody-targeting of Tie1 may prove critical in such combinations.
A Facile Synthesis ofO-[(3-Methyloxetan-3-yl)-methyl]hydroxylamine (2015)

Since the first report of its preparation in 1878,1 oxetane has been widely used in polymer synthesis.2–4 Of particular note, C(3)-substituted oxetanes5 readily deliver polyether glycols with the C...
Recién nacido con pénfigo sifilítico en tiempos de pandemia (2021)

Congenital syphilis is the infection by Treponema pallidum of the newborn, due to mother-to-child transmission of spirochaetes during pregnancy. It remains as a major cause of preventable fetal and neonatal morbidity and mortality if the mother is not opportunely treated. This highlights the importance of an adequate prenatal control, early screening for maternal infection and timely treatment. Although Chile has experienced an increase in the incidence of syphilis in the general population, a stable rate of congenital syphilis in 0.1/1.000 live births has been maintained. In this case report, we present a newborn whose mother did not have antenatal control and showed dermatological lesions compatible with syphilitic pemphigus.
Persistent Organic Pollutant-Mediated Insulin Resistance (2019)

Persistent organic pollutants (POPs) such as organochlorine (OC) pesticides, polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) have become wide-spread environmental contaminants as a consequence of their extensive use, long-range transport, and persistence. Because POPs are highly resistant to metabolic degradation, humans bioaccumulate these lipophilic and hydrophobic pollutants in fatty tissues for many years. Previous studies have demonstrated that POPs including PCBs are involved in the development of diabetes mellitus (DM) type 2 and insulin resistance. Numerous epidemiological studies suggest an association between POP burden and DM type 2/metabolic syndrome. In addition, several experimental studies have provided additional evidence supporting the association between POP exposure and DM type 2 or insulin resistance. Epidemiological and experimental studies have provided compelling evidence indicating that exposure to POPs increases the risk of developing insulin resistance and metabolic disorders. However, the detailed molecular mechanism underlying POP-induced insulin resistance is yet to be elucidated. In this article, we review literature that has reported on the association between POP burden and insulin resistance and the mechanism underlying POP-induced insulin resistance, and discuss implications for public health.
Sepsis causes right ventricular myocardial inflammation independent of pulmonary hypertension in a porcine sepsis model (2019)

Prominent PAH should therefore not exclude porcine sepsis models to further our understanding of human sepsis.
Representative immunofluorescence histological findings of tauopathy model mice and wild type mice. (2015)

&lt;p&gt;Male mice 4 months of age: Tauopathy model mice (A–D), and wild type mice (E–H). Lateral globus pallidus (A, E), anterior cortical amygdaloid nucleus (B, F), auditory cortex (C, G), and ventral hippocampus (CA3; D, H). Scale Bar: 100 µm.&lt;/p&gt;
Probing higher order optical modes in all‐dielectric nanodisk, ‐square, and ‐triangle by aperture type scanning near‐field optical microscopy (2021)

All-dielectric nanoantennas, consisting of high refractive index semiconductor material, are drawing a great deal of attention in nanophotonics. Owing to their ability to manipulate efficiently the flow of light within sub-wavelength volumes, they have become the building blocks of a wide range of new photonic metamaterials and devices. The interaction of the antenna with light is largely governed by its size, geometry, and the symmetry of the multitude of optical cavity modes it supports. Already for simple antenna shapes, unraveling the full modal spectrum using conventional far-field techniques is nearly impossible due to the spatial and spectral overlap of the modes and their symmetry mismatch with incident radiation fields. This limitation can be circumvented by using localized excitation of the antenna. Here, we report on the experimental near-field probing of optical higher order cavity modes (CMs) and whispering gallery modes (WGMs) in amorphous silicon nanoantennas with simple, but fundamental, geometrical shapes of decreasing rotational symmetry: a disk, square, and triangle. Tapping into the near-field using an aperture type scanning near-field optical microscope (SNOM) opens a window on a rich variety of optical patterns resulting from the local excitation of antenna modes of different order with even and odd parity. Numerical analysis of the antenna and SNOM probe interaction shows how the near-field patterns reveal the node positions of - and allows us to distinguish between - cavity and whispering gallery modes. As such, this study contributes to a richer and deeper characterization of the structure of light in confined nanosystems, and their impact on the structuring of the light fields they generate.
Multi-ancestry genetic study in 5,876 patients identifies an association between excitotoxic genes and early outcomes after acute ischemic stroke (2020)

<b>Evidence before this study:</b> No previous genome-wide association studies have investigated the genetic architecture of early outcomes after ischemic stroke.<b>Added Value of this study:</b> This is the first study that investigated genetic influences on early outcomes after ischemic stroke using a genome-wide approach, revealing seven genome-wide significant loci. A unique aspect of this genetic study is the inclusion of all of the major ethnicities by recruiting from participants throughout the world. Most genetic studies to date have been limited to populations of European ancestry.<b>Implications of all available evidence:</b> The findings provide the first evidence that genes implicating excitotoxicity contribute to human acute ischemic stroke, and demonstrates proof of principle that GWAS of acute ischemic stroke patients can reveal mechanisms involved in ischemic brain injury.
Safety-Critical Online Control with Adversarial Disturbances (2020)

This paper studies the control of safety-critical dynamical systems in the presence of adversarial disturbances. We seek to synthesize state-feedback controllers to minimize a cost incurred due to the disturbance while respecting the safety constraint. The safety constraint is given by a bound on an H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">∞</sub> norm, while the cost is specified as an upper bound on an H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> norm of the system. We consider an online setting where costs at each time are revealed only after the controller at that time is chosen. We propose an iterative approach to the synthesis of the controller by solving a modified discrete-time Riccati equation. Solutions of this equation enforce the safety constraint. We compare the cost of this controller with that of the optimal controller when one has complete knowledge of disturbances and costs in hindsight. We show that the regret function, which is defined as the difference between these costs, called varies logarithmically with the time horizon. We validate our approach on a process control setup that is subject to two kinds of adversarial attacks.
Anodal stimulation: an underrecognized cause of nonresponders to cardiac resynchronization therapy. (2011)

Anodal stimulation is a potential underrecognized and ameliorable cause of poor response to CRT.
KEPCO's distribution automation system (2006)

The distribution automation system (DAS) will provide supervision and remote control of switches and reclosers such as pole mounted switches and pad mounted switchgears on high voltage distribution line. This can be controlled remotely either automatically or manually, so that it can provide automatic isolation of faulty line sections, which enables quick and accurate recovery of a stable power supply, and also minimizes the out-of-service areas to units of distribution sections. (7 pages)
The Cancer Diaspora: Metastasis beyond the seed and soil hypothesis (2013)

Do cancer cells escape their confinement of their original habitat in the primary tumor or are they forced out by ecological changes in their home niche? Describing metastasis in terms of a simple one-way migration of cells from the primary to target organs is an insufficient concept to cover the nuances of cancer spread. A diaspora is the scattering of people away from an established homeland. To date, diaspora has been a uniquely human term utilized by social scientists, however, the application of the diaspora concept to metastasis may yield new biological insights as well as therapeutic paradigms. The diaspora paradigm takes into account and models several variables: the quality of the primary tumor microenvironment, the fitness of individual cancer cell migrants as well as migrant populations, the rate of bidirectional migration of cancer and host cells between cancer sites, and the quality of the target microenvironments to establish metastatic sites. Ecological scientific principles can be applied to the cancer diaspora to develop new therapeutic strategies. For example, ecological traps, habitats that lead to the extinction of a species, can be developed to attract cancer cells to a place where they can be better exposed to treatments or to cells of the immune system for improved antigen presentation. Merging the social science concept of diaspora with ecological and population sciences concepts can inform the cancer field to understand the biology of tumorigenesis and metastasis and inspire new ideas for therapy.
Exit plane H2O concentration measurements correlated with OH PLIF near-injector mixing measurements for scramjet flows (1992)

Mixing and combusting high enthalpy flows, similar to those encountered in scramjet engines, were investigated using a shock tunnel to produce the flow in conjunction with non-intrusive optical diagnostics which monitored the performance of two injector configurations. The shock tunnel is configured to produce Mach 3 flow and stagnation enthalpies corresponding to flight equivalent Mach numbers between 7 and 11. A pulsed hydrogen injection capability and interchangeable injector blocks provide a means of examining high speed, high enthalpy reacting flows. Planar laser induced fluorescence (PLIF) of OH molecules in the near injector region produced images which show the combusting and mixing zones for the reacting flow. Line-of-sight exit plane measurement of water concentration and temperature were used to provide a unique method of monitoring exit plane products. These results demonstrated that a velocity matched axial injection system produced a fuel jet that lifted off the floor of the duct. Mixing was observed to increase for this system as a velocity mismatch was introduced. Comparison of exit plane water concentrations for a wall jet injection system and a velocity matched injection system indicated similar mixing performance but an accurate pressure measurement is necessary to further validate the result. In addition, exit plane measurements indicated an approximate steady-state condition was achieved during the 1 to 2 ms test times.
Area Efficient Computing-in-Memory Architecture Using STT/SOT Hybrid Three Level Cell (2022)

Spintronic-based computing-in-memory (CiM) architecture has emerged as one of the efficient solutions to counter the latency/bandwidth bottleneck of conventional von-Neumann architecture. However, computation within a small area while achieving low power consumption still remains a challenge. Multi-bit spintronic storage device is a suitable solution to improve the integration density of such architectures. This paper focuses on using spin-transfer torque (STT)/spin-orbit torque (SOT) based hybrid three-level cell (TLC) in CiM application for implementing logic circuits such as AND, XOR, and magnetic full adder (MFA). Moreover, the performance of the STT/SOT-TLC-based MFA is compared with other full adder designs. The results show that the proposed MFA is 75% more area-efficient in comparison to two-bit STT and SOT-based designs, and 50% more area-efficient in comparison to differential spin hall effect (DSHE) based designs
Low Temperature Acclimation in the Desert Spider, Agelenopsis aperta (Araneae, Agelenidae) (1985)

(Uploaded by Plazi from the Biodiversity Heritage Library) No abstract provided.
Long carbon chain molecules in circumstellar shells (1987)

It has been proposed that long-chain carbon molecules abundant in various interstellar regions can be produced by facile reactions between carbon clusters produced by graphite vaporization and the simpler reagents present in the ISM. The results of recent laboratory experiments which support this hypothesis are reviewed. The properties of the species of linear carbon chains, spherical shell carbon clusters, and macroscopic particles produced in these experiments are summarized. The experiments show that high-temperature processes are a viable simultaneous source of polyynes as well as carbonaceous grains. In particular, they suggest that wherever polyynes are abundant, the associated grains are likely to be carbonaceous and that both may be of circumstellar origin.
Starch-Branching Enzymes Preferentially Associated with A-Type Starch Granules in Wheat Endosperm (2000)

Abstract Two starch granule-bound proteins (SGP), SGP-140 and SGP-145, were preferentially associated with A-type starch granules (&amp;gt;10 μm) in developing and mature wheat (Triticum aestivum) kernels. Immunoblotting and N-terminal sequencing suggested that the two proteins were different variants of SBEIc, a 152-kD isoform of wheat starch-branching enzyme. Both SGP-140 and SGP-145 were localized to the endosperm starch granules but were not found in the endosperm soluble fraction or pericarp starch granules younger than 15 d post anthesis (DPA). Small-size starch granules (&amp;lt;10 μm) initiated before 15 DPA incorporated SGP-140 and SGP-145 throughout endosperm development and grew into full-size A-type starch granules (&amp;gt;10 μm). In contrast, small-size starch granules harvested after 15 DPA contained only low amounts of SGP-140 and SGP-145 and developed mainly into B-type starch granules (&amp;lt;10 μm). Polypeptides of similar mass and immunologically related to SGP-140 and/or SGP-145 were also preferentially incorporated into A-type starch granules of barley (Hordeum vulgare), rye (Secale cereale), and triticale (× Triticosecale Wittmack) endosperm, which like wheat endosperm have a bimodal starch granule size distribution.
Stereoselective Synthesis of C‐Ketosides by Lewis Acid Catalyzed C‐Glycosylation of Alkynyl‐Ketoses. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Analyzing Massive Machine Maintenance Data in a Computing Cloud (2011)

We present a novel framework, CloudView, for storage, processing and analysis of massive machine maintenance data, collected from a large number of sensors embedded in industrial machines, in a cloud computing environment. This paper describes the architecture, design, and implementation of CloudView, and how the proposed framework leverages the parallel computing capability of a computing cloud based on a large-scale distributed batch processing infrastructure that is built of commodity hardware. A case-based reasoning (CBR) approach is adopted for machine fault prediction, where the past cases of failure from a large number of machines are collected in a cloud. A case-base of past cases of failure is created using the global information obtained from a large number of machines. CloudView facilitates organization of sensor data and creation of case-base with global information. Case-base creation jobs are formulated using the MapReduce parallel data processing model. CloudView captures the failure cases across a large number of machines and shares the failure information with a number of local nodes in the form of case-base updates that occur in a time scale of every few hours. At local nodes, the real-time sensor data from a group of machines in the same facility/plant is continuously matched to the cases from the case-base for predicting the incipient faults-this local processing takes a much shorter time of a few seconds. The case-base is updated regularly (in the time scale of a few hours) on the cloud to include new cases of failure, and these case-base updates are pushed from CloudView to the local nodes. Experimental measurements show that fault predictions can be done in real-time (on a timescale of seconds) at the local nodes and massive machine data analysis for case-base creation and updating can be done on a timescale of minutes in the cloud. Our approach, in addition to being the first reported use of the cloud architecture for maintenance data storage, processing and analysis, also evaluates several possible cloud-based architectures that leverage the advantages of the parallel computing capabilities of the cloud to make local decisions with global information efficiently, while avoiding potential data bottlenecks that can occur in getting the maintenance data in and out of the cloud.
Compressed cyclostationary detection for Cognitive Radio (2017)

Cognitive Radio requires both efficient and reliable spectrum sensing of wideband signals. In order to cope with the sampling rate bottleneck when dealing with such signals, sub-Nyquist methods have been proposed. However, these techniques decrease the signal to noise ratio (SNR) due to aliasing effects. Cyclostationary detection, which exploits the periodic property of communication signal statistics, absent in stationary noise, is a natural candidate for this setting. In this work, we consider cyclic spectrum recovery from sub-Nyquist samples, in order to achieve both efficiency and robustness to noise. We show how the cyclic spectrum can be recovered directly from the low rate samples, even for non sparse signals, and derive a lower bound on the sampling rate required for perfect cyclic spectrum recovery in the presence of stationary noise. Simulations show that cyclostationary detection outperforms energy detection in low SNRs in the sub-Nyquist regime.
Preparation, Characterization, and Evaluation of Ioxilan Carbonate Particles for Computed Tomography Contrast Enhancement of Liver (1994)

Development of particulate contrast medium from nonionic contrast agents represents a new approach. Ioxilan carbonate particles have suitable physicochemical properties that warrant further studies before clinical evaluation.
Expression of a Human IgG4 Antibody, BAB2, with Specificity for the Major Birch Pollen Allergen, Bet v 1 in Escherichia coli: Recombinant BAB2 Fabs Enhance the Allergic Reaction (1999)

The demonstration that anti-allergen IgG antibodies can also enhance IgE binding to a given allergen explains the unpredictability of specific immunotherapy as well as the controversy on the role of IgG in atopy.
Miniaturization and integration of photoacoustic detection (2002)

Photoacoustic spectroscopy is an absorption spectroscopy technique that is currently used for low-level gas detection and catalyst characterization. It is a promising technique for chemical analysis in mesoscale analysis systems because the detection limit scales favorably with miniaturization. This work focuses on the scaling properties of photoacoustic spectroscopy, and on the miniaturization of gas-phase photoacoustic detection of propane in a nitrogen ambient. The detection system is modeled with a transmission line analogy, which is verified experimentally. The model includes the effects of acoustic leaks and absorption saturation. These two phenomena degrade the performance of the photoacoustic detector and must be controlled to realize the scaling advantages of photoacoustic systems. The miniature brass cells used to verify the model employ hearing aid microphones and optical excitation from a mechanically chopped, 3.39 μm He–Ne laser, transmitted into the cells with an optical fiber. These cells are able to detect 10 ppm of propane in nitrogen (a signal level of ∼1 Pa/W). We also describe the development of a miniaturized photoacoustic system formed by microfabrication. In this case, the pressure-driven deflection of the detection membrane is measured optically. These systems show that photoacoustic detection may be inappropriate for systems with large variations in gas concentration because of absorption saturation and changing gas acoustic properties. Nevertheless, photoacoustic spectroscopy is a promising technique for the analysis of dilute mixtures in miniature chemical systems.
Detection Properties of Partial Discharge-emitted Electromagnetic Waves in Silicone Gels during the Electric Trees Development to Breakdown (2022)

In this study, the electromagnetic (EM) waves radiated by partial discharges from the electrode system placed in two types of silicone gels were measured with two different antennas with different bandwidths. The results showed that the EM waves radiated by partial discharge (PD) during electrical tree progression could be obtained in each gel, and that amplitude of the EM waves differed depending on the antenna type as well as the gel type. This result suggests that frequency bandwidth of the sensor or antenna should be selected to detect the EM waves radiated by PDs in gel insulator effectively.
On the Number of Factorizations of Polynomials over Finite Fields (2020)

Motivated by coding applications, two enumeration problems are considered: the number of distinct divisors of a degree-m polynomial over F = GF(q), and the number of ways a polynomial can be written as a product of two polynomials of degree at most n over F. For the two problems, bounds are obtained on the maximum number of factorizations, and a characterization is presented for polynomials attaining that maximum. Finally, expressions are presented for the average and the variance of the number of factorizations, for any given m (resp., n).