gebhart/patrepeval huggingface dataset:
Aqueous Pu(IV) sorption on brucite (2000)

The sorption behavior of aqueous Pu(IV) on brucite (Mg(OH) 2 ) in the presence and absence of citrate was investigated by a combination of wet chemical batch sorption experiments and X-ray photoelectron spectroscopy (XPS). Sorption occurs rapidly at near 100% levels from pH 8 to pH 13, and is not affected by the presence of citrate. XPS results indicate that Pu was incorporated in the subsurface in the cases studied.
Development of a Novel Inflammation-Based Index for Hepatocellular Carcinoma (2019)

ILIS is an HCC-specific prognostic index built on 5 readily available blood parameters. Its versatility is validated both Eastern and Western population of HCC. The score is correlated with levels of circulating cytokines.
Celecoxib But Not Rofecoxib Inhibits the Growth of Transformed Cells in Vitro (2004)

Celecoxib may prove to be a very efficient component in the prevention and treatment of gastrointestinal tumors because it inhibits the growth of cancerous cells without affecting the growth of normal cells.
Cardiac magnetic resonance versus transthoracic echocardiography for the assessment of cardiac volumes and regional function after myocardial infarction: an intrasubject comparison using simultaneous intrasubject recordings (2009)

This intra subject comparison after MI found large, systematic differences between CMR and echo measures of volumes, LVEF, and wall motion abnormality despite moderate inter-modality correlations, with echo underestimating each metric. CMR also provided superior detection and quantification of segmental function after MI. Serial studies of LV function in individual patients should use the same modality.
The Effect of Education on the Assessment of Optic Nerve Head Photographs for the Glaucoma Diagnosis (2011)

CME had only a small effect on the assessment of ONH for the glaucoma diagnosis. Sensitivity increased and the amount of uncertain classifications decreased, while specificity was unchanged.
High Repetition Rate, LINAC-Based Nuclear Resonance Fluorescence FY 2008 Final Report (2008)

This summarizes the first year of a multi-laboratory/university, multi-year effort focusing on high repetition rate, pulsed LINAC-based nuclear resonance fluorescence (NRF) measurements. Specifically, this FY2008 effort centered on experimentally assessing NRF measurements using pulsed linear electron accelerators, operated at various repetition rates, and identifying specific detection requirements to optimize such measurements. Traditionally, interest in NRF as a detection technology, which continues to receive funding from DHS and DOE/NA-22, has been driven by continuous-wave (CW), Van de Graff-based bremsstrahlung sources. However, in addition to the relatively sparse present-day use of Van de Graff sources, only limited NRF data from special nuclear materials has been presented; there is even less data available regarding shielding effects and photon source optimization for NRF measurements on selected nuclear materials.
Concerning the Localization of End Groups in Dendrimers (1998)

The different generations of BOC-protected glycine-functionalized PAMAM dendrimers were studied, crystal structure of the 1st generation dendrimer was obtained, and the amt. of H bonds was estd. The x-ray structure shows multiple interactions between the different end groups of the dendrimer, modeling the shell of a higher generation dendrimer. Spectroscopic results from solns. of all dendrimers of all generations confirm the close proximity of end groups
Transition-Metal-Catalyzed Arene Alkylation and Alkenylation: Catalytic Processes for the Generation of Chemical Intermediates (2020)

ADVERTISEMENT RETURN TO ISSUEPREVViewpointNEXTTransition-Metal-Catalyzed Arene Alkylation and Alkenylation: Catalytic Processes for the Generation of Chemical IntermediatesT. Brent Gunnoe*T. Brent GunnoeDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States*Email for T.B.G.: [email protected]More by T. Brent Gunnoehttp://orcid.org/0000-0001-5714-3887, William L. Schinski*William L. SchinskiDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United States*Email for W.L.S.: [email protected]More by William L. Schinski, Xiaofan JiaXiaofan JiaDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United StatesMore by Xiaofan Jiahttp://orcid.org/0000-0003-0425-5089, and Weihao ZhuWeihao ZhuDepartment of Chemistry, University of Virginia, Charlottesville, Virginia 22904, United StatesMore by Weihao ZhuCite this: ACS Catal. 2020, 10, 23, 14080–14092Publication Date (Web):November 18, 2020Publication History Received10 August 2020Published online18 November 2020Published inissue 4 December 2020https://pubs.acs.org/doi/10.1021/acscatal.0c03494https://doi.org/10.1021/acscatal.0c03494article-commentaryACS PublicationsCopyright © 2020 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views4886Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (1 MB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Aromatic compounds,Catalysts,Hydrocarbons,Organic reactions,Styrenes Get e-Alerts
Formulation of low clinker blended cements and concrete with enhanced fresh and hardened properties (2021)

Blended cements appear as the most promising way to massively produce cements with reduced environmental footprints. However, considering the generally lower early mechanical performance of highly blended cements, chemical admixtures are increasingly relied upon to increase early strength. However, in many cases this can negatively impact other properties as rheology and durability. This paper proposes an approach to formulate low clinker cements and concrete using moderate alkali activation or gypsum to enhance early and long-term compressive strength, without inducing excessive alkali-silica reaction (ASR) expansion. It examines blended cements containing burnt oil shale along with limestone and fly ash or slag as supplementary cementitious materials. It optimizes the combination of polycarboxylate ether (PCE) superplasticizers with the strength enhancers. Along with the use of Ca(NO3)2 to drive PCE adsorption, this provides good rheology control, increased early and long-term compressive strength, as well as acceptable ASR expansion in cements with only 50% clinker.
Implementing hospital-based surveillance for severe acute respiratory infections caused by influenza and other respiratory pathogens in New Zealand (2014)

Hospital-based SARI surveillance has been implemented and is fully functioning in New Zealand. Active, prospective, continuous, hospital-based SARI surveillance is useful in supporting pandemic preparedness for emerging influenza A(H7N9) virus infections and seasonal influenza prevention and control.
Uncovering the ultimate performance of single-walled carbon nanotube films as transparent conductors (2015)

The ultimate performance—ratio of electrical conductivity to optical absorbance—of single-walled carbon nanotube (SWCNT) transparent conductive films (TCFs) is an issue of considerable application relevance. Here, we present direct experimental evidence that SWCNT bundling is detrimental for their performance. We combine floating catalyst synthesis of non-bundled, high-quality SWCNTs with an aggregation chamber, in which bundles with mean diameters ranging from 1.38 to 2.90 nm are formed from identical 3 μm long SWCNTs. The as-deposited TCFs from 1.38 nm bundles showed sheet resistances of 310 Ω/□ at 90% transparency, while those from larger bundles of 1.80 and 2.90 nm only reached values of 475 and 670 Ω/□, respectively. Based on these observations, we elucidate how networks formed by smaller bundles perform better due to their greater interconnectivity at a given optical density. Finally, we present a semi-empirical model for TCF performance as a function of SWCNT mean length and bundle diameter. This gives an estimate for the ultimate performance of non-doped, random network mixed-metallicity SWCNT TCFs at ∼80 Ω/□ and 90% transparency.
Interpreting TF-IDF term weights as making relevance decisions (2008)

A novel probabilistic retrieval model is presented. It forms a basis to interpret the TF-IDF term weights as making relevance decisions. It simulates the local relevance decision-making for every location of a document, and combines all of these “local” relevance decisions as the “document-wide” relevance decision for the document. The significance of interpreting TF-IDF in this way is the potential to: (1) establish a unifying perspective about information retrieval as relevance decision-making; and (2) develop advanced TF-IDF-related term weights for future elaborate retrieval models. Our novel retrieval model is simplified to a basic ranking formula that directly corresponds to the TF-IDF term weights. In general, we show that the term-frequency factor of the ranking formula can be rendered into different term-frequency factors of existing retrieval systems. In the basic ranking formula, the remaining quantity - log p (r¯| t ∈ d ) is interpreted as the probability of randomly picking a nonrelevant usage (denoted by r¯) of term t . Mathematically, we show that this quantity can be approximated by the inverse document-frequency (IDF). Empirically, we show that this quantity is related to IDF, using four reference TREC ad hoc retrieval data collections.
ChemInform Abstract: Synthesis of the Pyridine Core of Cyclothiazomycin. (2011)

Abstract Key step is the regioselective [2 + 2 + 2] cycloaddition of nitrile (II) to the diyne (I).
Proposal of Coupled Ring Resonator Based on One-Dimensional Photonic Crystal Nanocavity (2013)

We propose the coupled ring resonator based on one-dimensional photonic crystal (1-D PC) nanocavity. The proposed structure is composed by introducing 1-D PC nanocavity into the CROW based on ring resonator, and we expect that it can achieve small group velocity. We investigate the transmission characteristics of the proposed structure by using 2-D scalar finite element method (FEM) for periodic waveguide analysis. We obtained the group velocity <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">vg</i> = 0.033 <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</i> with <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</i> being light velocity in vacuum because of combining 1-D PC nanocavity and CROW based on ring resonator. Moreover, we consider reduction of footprint of the proposed structure for photonic integration.
Analysis of the Electric Field-Dependent Current During Electroporation Pulses (2020)

When delivered across a cell, certain pulsed electric fields can cause an increase in the cell membrane permeability through a biophysical process known as electroporation. The current signals during the electric pulses could be used as a method for noninvasive electroporation measurement because of the sharp change in the conductivity of cells due to electroporation. To add to the existing knowledge on electroporation current signals under different pulse parameters, we undertook a study in which the electric current across the cells was recorded during electroporation pulses. The experimental current response to a pulsed electric field consisted of three stages: a) a rapid initial increase followed by b) an exponential decrease and then c) a monotonic increase. The rise time of the current signals was not affected by the intensity of the electric field or the number of pulses. However, the time at which the current increased again, deemed the electroporation onset time, shortened as the electric field became more intense and as the number of pulses increased. The transient conductivity change rate, defined to describe the electroporation degree during the pulse, increased under a higher electric field strength. However, the transient conductivity change rate first decreased and then gradually increased with additional pulses. This work may provide insight into the change in current during real-time electroporation detection.
Scapular Notching in Reverse Shoulder Arthroplasty: Is It Important to Avoid It and How? (2010)

Level IV, Therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
The HBx protein expression in liver cancer (1993)

The expression of HBx protein in liver tissues from 48 cases of different liver diseases, including 32 cases of hepatocellular carcinoma (HCC), 10 of chronic hepatitis (CH), 2 of angioma and 4 cases of normal liver was studied. These samples were tested for HBx protein, HBsAg by modified ABC method. Positive rates of HBx in cancer and adjacent liver tissue were 75.0% and 62.5%, and positive rates of HBsAg were 37.5% and 78.1% respectively. The occurrence of HBx in the absence of HBsAg was more frequently observed in tissues from HCC (46.9%) than CH (0%). The results showed that expression of HBx was more active than that of HBsAg, and it is suggested that HBx might be a useful marker for the diagnosis of liver cancer.
Local Wall Power Loading Variations in Thermonuclear Fusion Devices (1989)

AbstractA 2½-dimensional geometric model is presented that allows calculation of power loadings at various points on the first wall of a thermonuclear fusion device. Given average wall power loadings for bremsstrahlung, cyclotron radiation, charged particles, and neutrons, which are determined from various plasma physics computation models, local wall heat loads are calculated by partitioning the plasma volume and surface into cells and superimposing the heating effects of the individual cells on selected first-wall differential areas. Heat loads from the entire plasma are thus determined as a function of position on the first-wall surface.Significant differences in local power loadings were found for most fusion designs, and it was therefore concluded that the effect of local power loading variations must be taken into account when calculating temperatures and heat transfer rates in fusion device first walls.
<title>Feature space trajectory representation for active vision</title> (1997)

A new feature space trajectory (FST) description of 3D distorted views of an object is advanced for active vision applications. In an FST, different distorted object views are vertices in feature space. A new eigen-feature space and Fourier transform features are used. Vertices for different adjacent distorted views are connected by straight lines so that an FST is created as the viewpoint changes. Each different object is represented by a distinct FST. An object to be recognized is represented as a point in feature space; the closest FST denotes the class of the object, and the closest line segment on the FST indicates its pose. A new neural network is used to efficiently calculated distances. We discuss its uses in active vision. Apart from an initial estimate of object class and pose, the FST processor can specify where to move the sensor to: confirm close and pose, to grasp the object, or to focus on a specific object part for assembly or inspection. We advanced initial remarks on the number of aspect views needed and which aspect views are needed to represent an object.
Thermal gratings written in glycerol with CO_2 laser radiation (1989)

Real time holographic recording has been performed in glycerol using CO(2) laser beams for the writing. The dynamics of the grating formation was monitored with a reading beam at 632.8 nm. Particular attention has been paid on temporal behavior.
Safety of the Thrombopoiesis-Stimulating Agents for the Treatment of Immune Thrombocytopenia (2010)

The thrombopoiesis-stimulating agents (TSAs) are a novel class of drugs for the treatment of chronic immune thrombocytopenia (ITP). Roimplostim and eltrombopag, the first two TSAs to enter clinical use, received regulatory approval in 2008 and stand poised to change the treatment paradigm in ITP. However, important questions regarding the safety of these agents, particularly with long-term use, remain partially unanswered. The primary objective of this article is to review the reported toxicities associated with the TSAs including rebound thrombocytopenia, thrombosis, hepatotoxicity, formation of neutralizing antibodies, bone marrow fibrosis, hematologic malignancy, cataract formation, and common adverse events. The incidence and severity of these toxicities as well as strategies for monitoring patient safety and pharmacovigilance are discussed.
A Review of the Microbial Production of Bioactive Natural Products and Biologics (2019)

A variety of organisms, such as bacteria, fungi, and plants, produce secondary metabolites, also known as natural products. Natural products have been a prolific source and an inspiration for numerous medical agents with widely divergent chemical structures and biological activities, including antimicrobial, immunosuppressive, anticancer, and anti-inflammatory activities, many of which have been developed as treatments and have potential therapeutic applications for human diseases. Aside from natural products, the recent development of recombinant DNA technology has sparked the development of a wide array of biopharmaceutical products, such as recombinant proteins, offering significant advances in treating a broad spectrum of medical illnesses and conditions. Herein, we will introduce the structures and diverse biological activities of natural products and recombinant proteins that have been exploited as valuable molecules in medicine, agriculture and insect control. In addition, we will explore past and ongoing efforts along with achievements in the development of robust and promising microorganisms as cell factories to produce biologically active molecules. Furthermore, we will review multi-disciplinary and comprehensive engineering approaches directed at improving yields of microbial production of natural products and proteins and generating novel molecules. Throughout this article, we will suggest ways in which microbial-derived biologically active molecular entities and their analogs could continue to inspire the development of new therapeutic agents in academia and industry.
An Evaluation of Quality and Performance of Self-Piercing Riveted High Strength Aluminium Alloy AA6008 for Automotive Applications (2010)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Reducing vehicle weight, to improve fuel efficiency and reduce greenhouse gas emissions, continues to be a key objective in the automotive industry. As a result lightweight materials, such as aluminium alloys, are used increasingly for automotive body structures. Currently, self-piercing riveting (SPR) is a major technology used by manufacturers to join aluminium body structures. However, greater demands on the technology present themselves as ever higher strength alloys are required to be joined. The paper reported here focuses on the quality and performance of joints involving AA6008T61, recently introduced for potential applications in automotive body structures. In order to explore the process boundaries, AA6008T61 was supplied with different yield strength values which were obtained through different heat treatment procedures applied by the material supplier. As it is likely that mixed alloy combinations will be required to be joined, body structural aluminium alloy sheet AA5754 with different thicknesses was also be used through this project. The results suggested that SPR is capable of joining AA6008T61 as the top and middle layer with proper rivet/die combination. However, when AA6008T61 was used as the bottom layer, improper selection of die profile could lead to severe cracking. A new type of die with a truncated profile was proved to be able to relieve/improve the cracking situation. The severity of cracking on AA6008 T61 was dependent on the thickness of the top layer and the strength of the AA6008T61 itself. The results show that thinner top material thickness and/or stronger bottom material strength would produce more and larger cracks on the joint button. With the increasing of top material thickness, joint static strengths will increase, and the influence of bottom material strength on joint strength was not significant.&lt;/div&gt;&lt;/div&gt;
Synthesis of 2-S-dioxo isosters of purine and pyrimidine nucleosides (1978)

Preparation of glycosyl derivatives of 3, 5-diamino-4H-, 3,4,5 -triamino-, 3-amino-4-cyano-6H-1, 2, 6-thiadiazine 1,1-dioxide and 4-ethoxy-carbonyl- and 5-methyl-2H, 6H-1, 2, 6-thiadiazin-3-one 1, 1-dioxide is described. Glycosylation reactions of 7-amino-1H, 4H-imidazo[2,3-c]- and 7-amino-4H - furazano[3,4-c] [1, 2, 6]-thiadiazine 5,5-dioxide are also reported. Different synthetic pathways have been used and, in some cases, alkyl derivatives were prepared to be used as model substances in the elucidation of structures.
Reboxetine as an Optional Treatment for Hyperkinetic Conduct Disorder: A Prospective Open-Label Trial (2005)

Our findings suggest that reboxetine may be effective in the treatment of HCD and associated symptoms.
ChemInform Abstract: Transition Metal Heterocyclic Complexes. Part 2. Synthesis and Electrochemistry of Carbonyl Chromium Complexes in the Bithiophen Series. (1986)

Abstract The (substituted) (bithiophene)tricarbonyl‐Cr complexes (III) are formed upon treatment of tricarbonyltris(y‐picoline)‐Cr(0) (I) with the 2,2′‐bithiophenes (II) in the presence of the Lewis acid BF 3 .
A Free Volume Distribution Model of Gas Sorption and Dilation in Glassy Polymers (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Free Volume Distribution Model of Gas Sorption and Dilation in Glassy PolymersS. S. Jordan and W. J. KorosCite this: Macromolecules 1995, 28, 7, 2228–2235Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/ma00111a017https://doi.org/10.1021/ma00111a017research-articleACS PublicationsRequest reuse permissionsArticle Views617Altmetric-Citations93LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts