gebhart/patrepeval huggingface dataset:
Conscience, guilt and authenticity (2011)

A central Heideggerian claim is that conscience and guilt are fundamentally important human existentials because they reveal our authentic self-hood and the basis of freedom. The voice of conscience calls us to focus directly on our authentic self.
Analysis of Displayable Force Region at Passive-Type Force Display with Redundant Brakes – Development of Rehabilitation System for Upper Limbs mboxPLEMO-Y (Redundant) – (2018)

Robotic rehabilitation systems for upper limbs have been developed as two system types: active or passive. Active-type systems use actuators to provide users with varying degrees of force; in contrast, the force available from passive-type systems is limited, although these systems are safer to use. In this paper, a passive-type force display with redundant brakes is proposed to extend the displayable force region of the system. The kinematics and statics are derived, and the reaction force generated by brake torques is clarified. The displayable force region is analyzed in the simulation, and then the experiments are examined to verify the proposed analytical model.
Analyzing Radar Cross Section Signatures of Diverse Drone Models at mmWave Frequencies (2020)

In this work, we present quasi-monostatic Radar Cross Section measurements of different Unmanned Aerial Vehicles at 26-40 GHz. We study the Radar Cross Section signatures of nine different multi-rotor platforms as well as a single Lithium-ion Polymer battery. These results are useful in the design and testing of radar systems which employ millimeter-wave frequencies for superior drone detection. The data shows how radio waves are scattered by drones of various sizes and what impact the primary construction material has on the received Radar Cross Section signatures. Matching our intuition, the measurements confirm that larger drones made of carbon fiber are easier to detect, whereas drones made from plastic and styrofoam materials are less visible to the radar systems. The measurement results are published as an open database, creating an invaluable reference for engineers working on drone detection.
Cationic and anionic redox in lithium-ion based batteries (2020)

Lithium-ion batteries have proven themselves to be indispensable among modern day society. Demands stemming from consumer electronics and renewable energy systems have pushed researchers to strive for new electrochemical technologies. To this end, the advent of anionic redox, that is, the sequential or simultaneous redox of the cation and anion in a transition metal oxide based cathode for a Li-ion battery, has garnered much attention due to the enhanced specific capacities. Unfortunately, the higher energy densities are plagued with problems associated with the irreversibility of anionic redox. Much effort has been placed on finding a suitable composition of transition metal oxide, with some groups identifying the underlying features and relationship for anion redox and cationic redox to occur reversibly. Accordingly, it is timely to review anionic redox in terms of what anionic redox is with emphasis on the mechanism and the evidence underlying its discovery and validation. To follow will be a section defining the nature of the transition metal and oxygen bond accompanied by three subsequent sections bridging the redox spectrum from pure anionic, to a mix of cationic and anionic and pure cationic.
Thermal Stability of Plasma-Treated Ohmic Contacts to n-GaN (2003)

In this study, the thermal stability of plasma-treated ohmic contacts by either Cl2/Ar or Ar plasma to n-GaN was investigated by high-temperature aging tests. With proper plasma treatment, ohmic contacts to n-GaN have a lower contact resistance than those without plasma treatment. High-temperature aging tests were performed at temperatures ranging from 400 to 600°C for 2 h in N2 or air ambient. No apparent electrical degradation in contact resistance was observed after aging, showing the thermal stability of plasma-treated ohmic contacts is not affected by the recovery of plasma-induced damages on the wafer surface.
Probing the interaction interface of the GADD45β/MKK7 and MKK7/DTP3 complexes by chemical cross-linking mass spectrometry (2018)

GADD45β is selectively and constitutively expressed in Multiple Myeloma cells, and this expression correlates with an unfavourable clinical outcome. GADD45β physically interacts with the JNK kinase, MKK7, inhibiting its activity to enable the survival of cancer cells. DTP3 is a small peptide inhibitor of the GADD45β/MKK7 complex and is able to restore MKK7/JNK activation, thereby promoting selective cell death of GADD45β-overexpressing cancer cells. Enzymatic MS foot-printing and diazirine-based chemical cross-linking MS (CX-MS) strategies were applied to study the interactions between GADD45β and MKK7 kinase domain (MKK7_KD) and between DTP3 and MKK7_KD. Our data show that the binding between GADD45β and MKK7 largely occurs between GADD45β loop 2 (region 103-117) and the kinase enzymatic pocket. We also show that DTP3 interferes with this GADD45β/MKK7 interaction by contacting the MKK7 peptides, 113-136 and 259-274. Accordingly, an MKK7_KD Δ(101-136) variant lacking Trp135 did not produce a fluorescence quenching effect upon the binding of DTP3. The assessment of the interaction between GADD45β and MKK7 and the elucidation of the recognition surfaces between DTP3 and MKK7 significantly advance the understanding of the mechanism underlying the inhibition of the GADD45β/MKK7 interaction by DTP3 and pave the way to the design of small-molecule DTP3 analogues.
Reaction of Fischer type chromium carbene complexes with N,N-dimethylformamide dialkyl acetals (DMF-DAA): an unexpected carbon-carbon bond breaking (1993)

A series of pentacarbonyl(2-oxacyclopentylidene)chromium (5a-f) were reacted with N,N-dimethylformamide dimethyl acetal (DMF-DMA), resulting in the pentacarbonyl(2-oxa-5-[(N,N-dimethylamino)methylidenelcyclopentylideneJchromium (6a-f) and the unexpected pentacarbonyl(2-oxa-5-(cyclopropylmethylidene)cyclopentylidene)chromium (7a-d). Open chain Fischer type carbene complexes (CO)5CrC(OCH3)CH2R1 (1a-d) also react easily with DMF-DAA (2a-d). When R1 = H, the carbene complex (CO)5CrC(OCH3)CHCHN(CH3)2 is formed in high yield; however, when R1 = alkyl, the reaction products are dialkoxy complexes (CO)5CrC(OCH3)OR2 (4a-d), in which the OR2 group comes from the DMF-DAA. The mechanisms of the above reactions are elucidated. The cyclopropyl ring present on compounds 7a-d arises from a contraction of the five membered ring of complexes 5a-d due to the breaking of the bond between the carbene carbon atom and the α-carbon atom. The same mechanism explains the formation of dialkoxy complexes 4a-d from complexes 1b-d. In the case of the reaction of the complex (CO)5CrC(OCH3)CH2CH2CH2CH3 (1d) with N,N-dimethylformamide dineopentyl acetal (2d), the intermediary formation of an enamine derivative has been demonstrated. Moreover the reaction of pentacarbonyl(2-oxa-4,4-dimethylcyclopentylidene)-chromium (5g) with DMF-DMA (2a) allowed the isolation of 2,2-dimethylcyclopropanecarbaldehyde (characterized as the (2,4-dinitrophenyl)hydrazone)
Preinfusion polyfunctional anti-CD19 chimeric antigen receptor T cells are associated with clinical outcomes in NHL (2018)

After treatment with chimeric antigen receptor (CAR) T cells, interleukin-15 (IL-15) elevation and CAR T-cell expansion are associated with non-Hodgkin lymphoma (NHL) outcomes. However, the association of preinfusion CAR product T-cell functionality with clinical outcomes has not been reported. A single-cell analysis of the preinfusion CD19 CAR product from patients with NHL demonstrated that CAR products contain polyfunctional T-cell subsets capable of deploying multiple immune programs represented by cytokines and chemokines, including interferon-γ, IL-17A, IL-8, and macrophage inflammatory protein 1α. A prespecified T-cell polyfunctionality strength index (PSI) applied to preinfusion CAR product was significantly associated with clinical response, and PSI combined with CAR T-cell expansion or pretreatment serum IL-15 levels conferred additional significance. Within the total product cell population, associations with clinical outcomes were greater with polyfunctional CD4<sup>+</sup> T cells compared with CD8<sup>+</sup> cells. Grade ≥3 cytokine release syndrome was associated with polyfunctional T cells, and both grade ≥3 neurologic toxicity and antitumor efficacy were associated with polyfunctional IL-17A-producing T cells. The findings in this exploratory study show that a preinfusion CAR product T-cell subset with a definable polyfunctional profile has a major association with clinical outcomes of CAR T-cell therapy. This trial was registered at www.clinicaltrials.gov as #NCT00924326.
Quantum error detection .II. Bounds (2000)

In Part I of this paper we formulated the problem of error detection with quantum codes on the completely depolarized channel and gave an expression for the probability of undetected error via the weight enumerators of the code.In this part we show that there exist quantum codes whose probability of undetected error falls exponentially with the length of the code and derive bounds on this exponent.The lower (existence) bound is proved for stabilizer codes by the counting argument for classical self-orthogonal quaternary codes.Upper bounds are proved by linear programming.First we formulate two linear programming problems that are convenient for the analysis of specific short codes.Next we give a relaxed formulation of the problem in terms of optimization on the cone of polynomials in the Krawtchouk basis.We present two general solutions of the problem.Together they give an upper bound on the exponent of undetected error.The upper and lower asymptotic bounds coincide for a certain interval of code rates close to 1.
Solid-state piezochromism in poly(di-n-hexylgermane) (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSolid-state piezochromism in poly(di-n-hexylgermane)K. Song, R. D. Miller, and J. F. RaboltCite this: Macromolecules 1993, 26, 12, 3232–3233Publication Date (Print):June 1, 1993Publication History Published online1 May 2002Published inissue 1 June 1993https://pubs.acs.org/doi/10.1021/ma00064a041https://doi.org/10.1021/ma00064a041research-articleACS PublicationsRequest reuse permissionsArticle Views106Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Why the channel matrix in a LOS scenario has zero mean entries (2004)

During a recent measurement campaign, we encountered some problems in extracting the rice factor from measurements. There were different answers to the question of what constitutes the correct line-of-sight component. This document highlights those issues and is meant to be a basis of discussion. Any feedback on the raised issues is welcome.
Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor beta. (1994)

Precursor cells differentiate into mature CD4+ and CD8+ T cells in the inductive environment of the thymus by undergoing a series of distinct developmental steps marked by expression of the coreceptor molecules CD4 and CD8. Among the earliest cells to enter the CD4/CD8 developmental pathway are CD4-CD8lo precursors cells that differentiate into CD4+CD8+ thymocytes. Here we show that differentiation of precursor cells into CD4+CD8+ thymocytes requires at least one cell division and that their progression through a cell cycle is specifically retarded in the thymus by interaction with thymic epithelial cells that express transforming growth factor beta (TGF-beta) proteins. We also demonstrate that TGF-beta proteins, either in solution or bound to cell membranes, can regulate cell cycle progression and differentiation of CD4-CD8lo precursor cells into CD4+CD8+ thymocytes. The regulatory effect of TGF-beta is specific for CD4-CD8lo precursor cells as TGF-beta proteins do not regulate the earlier generation of CD4-CD8lo precursor cells from CD4-CD8- thymocytes. Finally, we demonstrate that TGF-beta proteins are expressed in vivo in the intact thymus on subcapsular and cortical thymic epithelium where they can contact developing CD4-CD8lo precursor cells. Thus, thymic epithelial cells expressing TGF-beta proteins can actively regulate the rate at which CD4+CD8+ thymocytes are generated from CD4-CD8lo precursor cells.
Evaluation of Long-Term Creep Rupture Life of Strength Enhanced High Cr Ferritic Steel on the Basis of Its Temperature Dependence (2013)

Abstract Conventional time-temperature-parameter (TTP) methods often overestimate long-term creep rupture life of creep strength enhanced high Cr ferritic steels. The cause of the overestimation is studied on the basis of creep rupture data analysis on Gr.91, 92 and 122 steels. There are four regions with different values of stress exponent n for creep rupture life commonly in stress-rupture data of the three ferritic steels. Activation energies Q for rupture life in the regions take at least three different values. The values of n and Q decrease in a longer-term region. The decrease in Q value is the cause of the overestimation of long-term rupture life predicted by the conventional TTP methods neglecting the change in Q value. Therefore, before applying a TTP method creep rupture data should be divided into several data sets so that Q value is unique in each divided data set. When this multi-region analysis is adopted, all the data points of the steels can be described accurately, and their long-term creep life can be evaluated correctly. Substantial heat-to-heat and grade-to-grade variation in their creep strength is suggested under recent service conditions of USC power boilers.
Performance comparisons of planar and volumetric observers for lesion detection in PET scanning (2003)

This work presents initial results of comparisons between planar and volumetric observer detection task performances for both human and model observers. Positron Emission Tomography (PET) imaging acquires and reconstructs tomographic images as contiguous volumetric (3D) images. Consequently physicians typically interpret these images by searching the image volume using linked orthogonal planar images in the three standard orientations (transverse, sagittal, and coronal). Most of observer studies, however, have typically used planar images for evaluation. For human observer ROC studies, an observer scoring tool, similar to the display tool being used in clinical PET oncology imaging, has been developed. For model observer studies the non-prewhitening matched filter (NPWMF) and the channelized Hotelling observer (CHO) were used to compute detectabilities as figures-of-merit for class separations. For the volumetric (3D)model observers, the entire image volume is used with appropriate 3D templates. For the planar (2D) model observers the transaxial plane centered on the target sphere is extracted and analyzed using 2D templates. Multiple realizations were generated using a non-Monte Carlo analytic simulator for feasible amount of simulation time and statistically accurate noise properties. For comparisons, the correlations between each model observer and human observer performance are computed. The result showed that 3D model observers have a higher correlation with human observers than 2D observers do when axial smoothing is not applied. With axial smoothing, however, the correlation of 2D model observers in general increased to the level of 3D model observer correlations with the human observer.
Geneticin Stabilizes the Open Conformation of the 5′ Region of Hepatitis C Virus RNA and Inhibits Viral Replication (2015)

The aminoglycoside Geneticin (G418) is known to inhibit cell culture proliferation, via virus-specific mechanisms, of two different virus genera from the family Flaviviridae. Here, we tried to determine whether Geneticin can selectively alter the switching of the nucleotide 1 to 570 RNA region of hepatitis C virus (HCV) and, if so, whether this inhibits viral growth. Two structure-dependent RNases known to specifically cleave HCV RNA were tested in the presence or absence of the drug. One was the Synechocystis sp. RNase P ribozyme, which cleaves the tRNA-like domain around the AUG start codon under high-salt buffer conditions; the second was Escherichia coli RNase III, which recognizes a double-helical RNA switch element that changes the internal ribosome entry site (IRES) from a closed (C) conformation to an open (O) one. While the drug did not affect RNase P activity, it did inhibit RNase III in the micromolar range. Kinetic studies indicated that the drug favors the switch from the C to the O conformation of the IRES by stabilizing the distal double-stranded element and inhibiting further processing of the O form. We demonstrate that, because the RNA in this region is highly conserved and essential for virus survival, Geneticin inhibits HCV Jc1 NS3 expression, the release of the viral genomic RNA, and the propagation of HCV in Huh 7.5 cells. Our study highlights the crucial role of riboswitches in HCV replication and suggests the therapeutic potential of viral-RNA-targeted antivirals.
Path to Eco-Driving: Electric Vehicle HVAC and Route Joint Optimization (2017)

This article targets at optimizing driving range and battery lifetime for EVs. The authors propose a scheme by which heating, ventilation, and air condition systems can be jointly optimized with driving routes while considering electric motors. -Zili Shao, The Hong Kong Polytechnic University.
Low phase-noise mid-infrared frequency combs based on microresonators (2013)

Summary form only given. The mid-infrared spectral range (λ~2-20 mm) is of particular importance as many molecules exhibit strong vibrational fingerprints in this region. Optical frequency combs [1, 2] - broadband optical sources consisting of equally spaced and mutually coherent sharp lines - are creating new opportunities for advanced spectroscopy [3, 4, 5]. Here we demonstrate a novel approach to create mid-infrared optical frequency combs via four-wave mixing [6, 7] in a continuous-wave pumped ultra-high Q crystalline microresonator made of magnesium fluoride [8]. Careful choice of the resonator material and design made it possible to generate a broadband, low-phase noise Kerr combs at λ=2.5 mm. With its distinguishing features of compactness, efficient conversion, large mode spacing and high power per comb line, this novel frequency comb source holds promise for new approaches to molecular spectroscopy and is suitable to be extended further into the mid-infrared.Crystalline MgF2 resonators are shaped and polished on an air-bearing spindle with diameters ranging from 500 μm to 5 mm, corresponding to a free spectral range of 10 to 100 GHz. Optical quality factors are typically on the order of Q~109. The resonators are pumped by several hundred milli-Watts of continuous-wave (CW) light at 2.45 μm and the comb lines spanning over more than 200 nm (~10 THz) are observed. Low phase-noise of the generated mid-infrared combs is confirmed by the heterodyne beat note measurement between a narrowlinewidth CW laser and the comb lines, as well as by transmission noise measurement. Intrinsically low phasenoise combs can be expected across the entire mid-infrared region. Combining with quantum cascade lasers (QCLs), this may facilitate a new class of frequency combs for molecular spectroscopy.
Subjective quality evaluations using crowdsourcing (2013)

This paper presents a system and methodology for crowdsourcing subjective quality evaluations. The goal of this work is to study the feasibility of fast, inexpensive, and reliable subjective quality evaluations with crowdsourcing. We present a web-based system for conducting subjective quality evaluations using crowdsourcing platform. The results were evaluated by comparison with the formal subjective tests conducted by MPEG as a part of video standardization process. High quality compressed videos with known MOS values are used as references in subjective evaluations instead of the original lossless videos to address the bandwidth limitations. The results show that crowdsourcing can be a reliable platform for subjective quality evaluations.
Computational SS and conversion protocols in both active and passive settings (2017)

Secret sharing (SS) has been extensively studied as both a means of secure data storage and a fundamental building block for multiparty computation (MPC). For these purposes, code‐efficiency and MPC‐suitability are required for SS but they are incomparable. Recently, a computational SS and a conversion protocol were proposed. The computational SS is code‐efficient and the conversion protocol converts shares of the computational (code‐efficient) SS into those of an MPC‐suitable SS, and it can be applied to reduce the amount of data storage while maintaining extendibility to MPC. However, this protocol is one‐way: one cannot convert the share of MPC output value. In addition, it is only passively secure. The authors propose three protocols and a new computational SS. The first protocol is the inverse of the existing protocol, that is, it converts an MPC‐suitable SS to the existing SS. The other two protocols are actively secure conversion protocols that convert shares between the new SS and an MPC‐suitable SS. The new computational SS is code‐efficient when the number of parties is small, so these two protocols are for converting between the code‐efficient SS and an MPC‐suitable SS. These two conversion protocols are actively secure in the honest majority.
Control of surface anchoring properties of liquid crystal by thermo-transfer printing of siloxane oligomers (2015)

We presented the results for the surface anchoring properties of a nematic liquid crystal (LC) in a wide range of the substrate wettability through thermo-transfer printing of siloxane oligomers. For the modification of the surface energy, poly(dimethylsiloxane) (PDMS) oligomers were directly transferred onto a glass substrate from a bulk PDMS plate by contact printing at elevated temperatures. The hydrophobicity of the PDMS-modified surface was found to increase with the temperature of the substrate during transfer printing. The LC alignment on the PDMS-modified substrate exhibited continuous variations of the pretilt angle from nearly 0° to 90° and the polar anchoring strength according to the surface energy.