gebhart/patrepeval huggingface dataset:
Optimal design-space exploration of streaming applications (2011)

Many embedded and scientific applications are pipelined (i.e., streaming) and deployed on application-specific systems. Typically, there are several design parameters in the algorithms and architectures used that impact the tradeoff between different metrics of application performance as well as resource utilization. Efficient automatic exploration of this design space is the goal of our research. We present a global optimization framework comprising a domain-specific variation of branch-and-bound that reduces search complexity by exploiting the topology of the application's pipelining. We exploit the topological information to discover decomposability through the canonical Jordan block form. The reduction in search complexity for four real-world streaming applications (drawn from the literature) is significant, ranging from a million-fold reduction in search space size to a reduction factor of 10 billion. All four optimization problems are thereby solvable in reasonable time.
Lower SRS Mental Health Scores are Associated With Greater Preoperative Pain in Patients With Adolescent Idiopathic Scoliosis (2019)

3.
Development of a novel neutron source with applications in calibration and monitoring. Final report (1995)

The objective of this research project, development of a unique portable inertial electrostatic confinement (IEC) neutron source (10{sup 6} 2.5-MeV neutrons/second-level) has been achieved. A majority of the experimental work required for the project was reported in the 1993 Annual Report. (The abstract and table of contents for that report arc included here as Appendix A for convenience. Full copies can be obtained upon request to the PI.) Unfortunately, the DOE program providing support for the project was canceled and funding was not available to continue the project in 199495. However, to provide time to explore some innovative potential applications for upgraded versions of the IEC, a no-cost extension of the contract was requested and granted in 1994. This follow-on work, mostly involving conceptual design studies, is reported here.
4D Force Detection of Cell Adhesion and Contractility (2023)

Mechanical signals establish two-way communication between mammalian cells and their environment. Cells contacting a surface exert forces via contractility and transmit them at the areas of focal adhesions. External stimuli, such as compressive and pulling forces, typically affect the adhesion-free cell surface. Here, we demonstrate the collaborative employment of Fluidic Force Microscopy and confocal Traction Force Microscopy supported by the Cellogram solver to enable a powerful integrated force probing approach, where controlled vertical forces are applied to the free surface of individual cells, while the concomitant deformations are used to map their transmission to the substrate. Force transmission across human cells is measured with unprecedented temporal and spatial resolution, enabling the investigation of the cellular mechanisms involved in the adaptation, or maladaptation, to external mechanical stimuli. Altogether, the system enables facile and precise force interrogation of individual cells, with the capacity to perform population-based analysis.
Re-engineering Primary Epithelial Cells from Rhesus Monkey Parotid Glands for Use in Developing an Artificial Salivary Gland (2006)

There is no satisfactory conventional treatment for patients who experience irreversible salivary gland damage after therapeutic radiation for head and neck cancer or because of Sjögren's syndrome. Additionally, if most parenchyma is lost, these patients also are not candidates for evolving gene transfer strategies. To help such patients, several years ago we began to develop an artificial salivary gland. In the present study, we used a non-human primate tissue source, parotid glands from rhesus monkeys, to obtain potential autologous graft cells for development of a prototype device for in situ testing. Herein, we present 3 major findings. First, we show that primary cultures of rhesus parotid gland (RPG) cells are capable of attaining a polarized orientation, with Na(+)/K(+)-adenosine triphosphatase, zonula occludens-1, and claudin-1 distributed in specific domains appropriate for epithelial cells. Second, we show that RPG cells exhibit 2 essential epithelial functions required for graft cells in an artificial salivary gland device (i.e., an effective barrier to paracellular water flow and the generation of a moderate transepithelial electrical resistance). Third, we show that RPG cells can express functional water channels, capable of mediating directional fluid movement, after transduction by adenoviral and adeno-associated virus type 2 vectors. Together these results demonstrate that it is feasible to individually prepare RPG cells for eventual use in a prototype artificial salivary gland.
Impact of the Preparation Procedure on the Performance of the Microporous HKUST-1 Metal-Organic Framework in the Liquid-Phase Separation of Aromatic Compounds (2020)

To date, metal-organic frameworks (MOFs) have been recognized as promising solid phases in high-performance liquid chromatography (HPLC). This research aimed to elucidate the role of the physico-chemical characteristics of the microporous HKUST-1 metal-organic framework in its operation as a selective adsorbent in HPLC. For this, the HKUST-1 samples were prepared by microwave-assisted synthesis and a solvothermal procedure. According to the chromatographic examinations, the HKUST-1 material synthesized in the microwave fields shows an efficient performance in the selective adsorption of aromatic compounds with different functionalities. This study revealed a significant impact of the preparation procedure on the mechanism of the liquid-phase adsorption on the HKUST adsorbents under conditions of the HPLC. An effect of the elution solvent with the different coordination ability to the Cu<sup>2+</sup> sites in the HKUST-1 structure on the adsorption selectivity was observed.
Optimisation et synthèse d'amplificateurs micro-ondes par la méthode des fréquences réelles (1988)

La méthode des « fréquences réelles » introduite par Carlin [1, 2] est basée uniquement sur la connaissance des paramètres de répartition S ij des transistors ; son utilisation ne nécessite aucun modèle de TEC. Le programme de CAO présenté utilise la procédure de Carlin. L'efficacité de la méthode, après modifications [3], permet aussi de concevoir des amplificateurs à plusieurs étages optimisés simultanément en gain et en TOS. Cette méthode tient compte de la non-unilatéralité des transistors.
Genotype turnover by reassortment of replication complex genes from avian Influenza A virus (2006)

Reassortment among the RNA segments of Influenza A virus caused the two most recent human influenza pandemics; recently, reassortment has generated viral genotypes associated with outbreaks of avian H5N1 influenza in Asia and Europe. A statistical analysis has been developed for the systematic identification and characterization of reassortant viruses. The analysis was applied to the genes of the replication complex of 152 avian influenza A viruses isolated between 1966 and 2004 from predominantly terrestrial and domestic aquatic avian species. The results indicated that reassortment among these genes was pervasive throughout this period and throughout both the Eurasian and North American lineages of the virus. Evidence is presented that the circulating genotypes of the replication complex are being replaced continually by novel genotypes created by reassortment. No constraints for coordinated reassortment among genes of the replication complex were evident; rather, reassortment almost always proceeded one segment at a time. A maximum-likelihood estimate of the rate of reassortment was derived. For significantly diverged Asian avian influenza A viruses from the period 1991-2004, it was estimated that the median duration between creation of a new genotype and its next segment reassortment was 3 years. Reassortments that introduced previously unobserved influenza genetic material were detected. These findings point to substantial potential for rapid generation of novel avian influenza A viruses, emphasizing the importance of intensive surveillance of these host species in preparation for a possible pandemic.
PET Fibers Modified with Cloisite Nanoclay (2020)

The alternative method of reducing the flammability of polyethylene terephthalate (PET) fibers, analogous to dyeing of PET fibers with dispersed dyes in a high-temperature bath, was proposed. A commercial organophilic montmorillonite Cloisite<sup>®</sup>15A (C15A) was applied as a flame retardant. The aim of the presented work was to evaluate the effectiveness of the introduced modifier and the improvement of the flame-retardant properties of PET fibers by limiting oxygen index (LOI) and thermogravimetric analysis (TGA) measurements. Evolved gas analysis (EGA) by spectrometric method (FTIR) during coupled thermogravimetric analysis (TGA) was applied in order to confirm no increase in the toxicity of volatile degradation products released from burning modified fibers. The nanocomposite nature of modified fibers was confirmed based on the structural parameters of the fibers determined using wide-angle X-ray scattering (WAXS) and small angle X-ray scattering (SAXS) X-ray diffraction methods.
Theory of microstructure and mechanics of the ...a1/a2/a1/a2... domain pattern in epitaxial ferroelectric and ferroelastic films (1996)

The micromechanics of the lamellar ...a1/a2/a1/a2... domain pattern are developed for the case of epitaxial tetragonal ferroelectric or ferroelastic films grown on (001) substrates. This problem is treated in the framework of the theory of defects. Coherency defects are necessary to maintain epitaxy as a result of the symmetry-reducing phase transition in the film (ferroelectric or ferroelastic transition). The defects include continuous distributions of edge and screw dislocations. The screw dislocation distributions are equivalent to an alternating Somigliana dislocation chain. Using this approach, fully analytic solutions are derived for the stress and strain in the film and substrate. These calculations include all the effects of the free surface. An integral expression is derived for the elastic energy. Using dipole and quadrupole approximations, analytic expressions are derived for the rotations of the crystal axes for individual domains, the elastic energy, and thickness dependence of the domain periodicity. We find, in agreement with previous work, that there is no critical thickness to form the ...a1/a2/a1/a2... domain pattern. For thick films the domain periodicity scales with the square root of the film thickness.
Supplementary Table S4 from Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with Guadecitabine (2023)

&lt;p&gt;Representativeness of Study Participants&lt;/p&gt;
Antimicrobial Activity and Chemical Composition of Melaleuca genistifolia Leaf Essential Oil from the Northern Plains of India (2008)

Biological and chemical investigations were carried out to evaluate the antimicrobial potential of Melaleuca genistifolia leaf oil for herbal medicines. The disk diffusion and micro broth dilution methods were used for the evaluation of the antimicrobial activity of the essential oil and its major constituent, methyl eugenol against the five selected bacterial and five fungal strains. The oil was active against all the tested bacterial and fungal strains. The oil was highly active against Staphylococcus epidermidis and significantly active against S. aureus, Sporothrix schenckii and Trichophyton rubrum, while methyl eugenol was significantly active against Enterococcus faecalis, Streptococcus mutans and Escherichia coli. GC and GC-MS analysis of the oil resulted in the identification of twenty two constituents representing 99.4% of the oil. The chemo type identified had a high methyl eugenol (88.1%) content. The essential oil could be of use for the future development of antimicrobial herbal products.
ChemInform Abstract: Synthesis of Analogues of Pepstatin. Effect of Structure in Subsites P1′, P2′ and P2 on Inhibition of Porcine Pepsin. (1984)

Abstract Pepstatin‐Analoga wie (I) und (II) werden synthetisiert und auf inhibierende Wirkung gegenüber Pepsin untersucht.
Phase Behavior of Isotactic Polypropylene−Poly(ethylene/ethylethylene) Random Copolymer Blends (1997)

The melt-state phase behavior of isotactic polypropylene (i-PP) blended with a series of poly(ethylene/ethylethylene) random copolymers has been investigated using small-angle neutron scattering (SANS). These PEExx copolymers, where xx is the percentage of ethylethylene (EE) units, were prepared by hydrogenation of anionically polymerized polybutadienes with controlled amounts of 1,2 addition. Random phase approximation (RPA) fits to the scattering data for blends of i-PP with a deuterated, low molecular weight PEE90 at 180 °C indicate a statistical segment length for i-PP that is 10% less than that reported previously. Scattering from blends of i-PP with higher molecular weight PEE90 and PEE73 at 180 °C can be quantitatively fit using the RPA theory with χ as the only adjustable parameter, indicating melt miscibility. PEE46 and PEE62 are strongly and marginally immiscible, respectively, with i-PP at 180 °C. These results establish a “window” in EE content in which these random copolymers can form single phase mixtures with i-PP.
Supplementary Figure S6 from Genomic Instability and Protumoral Inflammation Are Associated with Primary Resistance to Anti–PD-1 + Antiangiogenesis in Malignant Pleural Mesothelioma (2023)

&lt;p&gt;Cytotoxic response in tumor biopsies of patients with No DCB upon combination treatment.&lt;/p&gt;
Supplementary Table 1 from AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression (2023)

Supplementary Table 1 from AXL Is a Potential Target for Therapeutic Intervention in Breast Cancer Progression
Modeling intelligibility of hearing-aid compression circuits (2004)

The active filtering effect in the inner ear is disrupted with sensorineural hearing impairment. This causes a loss of frequency selectivity and dynamic range. Compression is often used in hearing-aids in an attempt to re-establish the normal dynamic range of the cochlear response. While some studies show increased speech intelligibility with artificial noise sources for compressive hearing-aids, most show little (< 1 dB versus linear aids) or no advantage in competing speech. In this paper we explore a quantitative model to explain the empirical performance of compressive hearing-aids in competing speech. By combining an accurate cochlear model with a model of higher auditory feature analysis based on spectral-temporal clustering of onsets, we provide an explanation for the failure of hearing-aid compression algorithms to increase intelligibility. Our proposed spectral-temporal intelligibility model suggests that increasing intelligibility for a hearing impaired person in competing speech requires both spectral and temporal suppression.
Supplementary Methods from Castration Resistance in Prostate Cancer Is Mediated by the Kinase NEK6 (2023)

&lt;p&gt;Description of additional methods and procedures used in the study.&lt;/p&gt;
THE INTEGRATIVE SURGICAL THEATER (2017)

Integration of OCT into the digital visualization system may enable unique opportunities for surgeon feedback of intraoperative diagnostics. The overlay of the OCT data onto the 4K monitor seemed to provide excellent visualization of OCT details. Further research is needed to compare the conventional microscope-based approach to the digital 3D screen approach in regards to intraoperative OCT.
Polycrystalline Thin Film Materials and Devices, Annual Subcontract Report, 16 January 1990 - 15 January 1991 (1991)

Results and conclusion of Phase I of a multi-year research program on polycrystalline thin film solar cells are presented. The research comprised investigation of the relationships among processing, materials properties and device performance of both CuInSe{sub 2} and CdTe solar cells. The kinetics of the formation of CuInSe{sub 2} by selenization with hydrogen selenide was investigated and a CuInSe{sub 2}/CdS solar cell was fabricated. An alternative process involving the reaction of deposited copper-indium-selenium layers was used to obtain single phase CuInSe{sub 2} films and a cell efficiency of 7%. Detailed investigations of the open circuit voltage of CuInSe{sub 2} solar cells showed that a simple Shockley-Read-Hall recombination mechanism can not account for the limitations in open circuit voltage. Examination of the influence of CuInSe{sub 2} thickness on cell performance indicated that the back contact behavior has a significant effect when the CuInSe{sub 2} is less than 1 micron thick. CdTe/CdS solar cells with efficiencies approaching 10% can be repeatedly fabricated using physical vapor deposition and serial post deposition processing. The absence of moisture during post deposition was found to be critical. Improvements in short circuit current of CdTe solar cells to levels approaching 25 mA/cm{sup 2} are achievable by making the CdS window layer thinner. Further reductions in the CdS window layer thickness are presently limited by interdiffusion between the CdS and the CdTe. CdTe/CdS cells stored without protection from the atmosphere were found to degrade. The degradation was attributed to the metal contact. CdTe cells with ZnTe:Cu contacts to the CdTe were found to be more stable than cells with metal contacts. Analysis of current-voltage and spectral response of CdTe/CdS cells indicates the cell operates as a p-n heterojunction with the diode current dominated by SRH recombination in the junction region of the CdTe.
Utilization of Natural Detergent Potassium Laurate for Decellularization in Lung Bioengineering (2019)

Recent advances in tissue engineering using decellularized organ scaffolds have expanded the possibilities for organ replacement therapy. However, detergent-based decellularization itself damages the extracellular matrix (ECM), which results in failure associated with the transplanted bioengineered organ. This study determined that potassium laurate (PL), a natural detergent, significantly reduces lung ECM damage during the decellularization process compared with protocols using sodium dodecyl sulfate. PL-decellularized lungs showed better microarchitecture preservation and low biological reactions after subcutaneous implantation. PL-decellularized scaffolds supported rat lung endothelial cell attachment/proliferation and the bioengineered lungs significantly reduced lung congestion after transplantation.
The Contribution of Thumbnail Image, Mouse-over Text and Spatial Location Memory to Web Page Retrieval in 3D. (1999)

We present an empirical evaluation of the contribution of pictorial image and spatial location information on the retrieval of previously stored web pages. Subjects were given 100 snapshots of web pages that they stored in spatial locations on an inclined plane in a desktop 3D environment (Data Mountain). We had them return and try to retrieve their pages again, using a variety of retrieval cues. Even though users had not seen their web page layout for several months, their retrieval times were not significantly slower. In addition, on half of the trials, stored pages were not presented as thumbnail images of the web pages but as blank icons. Taking the pictorial thumbnail images away initially led to a significant drop in subjects’ ability to find the pages, although within a short period of time subjects were able to find the pages equally fast without the thumbnail information. These results indicate that the use of 3D visualization techniques such as those described in this paper can lead to improved user memory for where favorite or frequently used information is stored in an electronic environment.
Contact dermatitis caused by prevention measures during the COVID-19 pandemic: a narrative review (2023)

This article reviews reports of CD caused by various prevention and hygiene measures during the COVID-19 pandemic. The amount of skin damage caused by COVID-19 prevention measures could be decreased by improved education about skin management.
Manipulating Ultra-High Definition Video Traffic (2015)

Compared to the widely deployed high-definition (HD) format, ultra-high definition (UHD) defines video parameters associated with higher spatial resolutions, higher frame rates, higher sample bit depths, and a wider color gamut. UHD promises to significantly enhance the user experience with pictures that offer the "look out the window"' effect. However, this promise comes at the cost of increased bandwidth required to deliver UHD. This article explores on-demand UHD video streaming using the latest video compression and delivery technologies. The proposed solution uses the scalable extensions of HEVC (SHVC) to efficiently compress, store, and deliver UHD video in a large-scale streaming system. With scalability, backward compatibility is maintained and the quality of the existing HD services is guaranteed.
Truncation completion of MR-based PET attenuation maps using time-of-flight non-attenuation-corrected PET images (2012)

TOF-NAC PET images produce a superior body contour as compared to non-TOF NAC PET images, thereby leading to more accurate truncation completion in the MR-derived attenuation map. We developed and systematically evaluated a procedure for truncation completion of MR-bases PET attenuation maps using body contours generated from TOF-NAC PET images. Fourteen clinical PET/CT and MR datasets from a tri-modality setup and fourteen PET/CT dual-modality datasets were used for this study.
An improved model for tip clearance loss in transonic axial compressors (2017)

An improved compressible model for estimating tip clearance loss in transonic compressors is presented with the emphasis on the effects of blade tip loading distribution and double leakage flow. Tip clearance flow is treated as three parts along the chord and the progressive relations from upstream to downstream part is revealed to be responsible for the formation of tip clearance flow. Control volume method is applied to simplify the mixing process and calculate the mixed-out loss for the three parts, separately. Computational study shows that mass flow of the incoming flow entering the control volume is consistent with that passing through an equivalent area of about half of tip leakage vortex region. The new model reveals that the second part of tip clearance flow has a larger mixed-out loss capacity than the two other parts. This difference is attributed to two factors: larger injection flow angle and more enrolled incoming flow, and both factors tend to increase the mixed-out loss. The success of the model implies that blade design or flow control strategies turning the tip clearance/main flow interface’s arrival onto blade tip pressure side downstream and the shock’s impingement point onto blade tip suction side upstream may be beneficial in desensitizing compressor performance to tip clearance size, without trading off pressure rise.
Practical variable step-size adaptive algorithms for echo cancellation (2009)

The most common algorithms used for echo cancellation are the normalized least-mean-square (NLMS) and the affine projection (AP). The classical versions of these algorithms use a constant step-size parameter and need to establish a tradeoff between several performance criteria e.g., high convergence rate versus low misadjustment. In this paper, we present a class of variable step-size NLMS and AP algorithms, which are designed to recover the near-end signal from the error of the adaptive filter. The simulation results indicate a robust behavior of these algorithms against the presence of the near-end signal.