gebhart/patrepeval huggingface dataset:
Dynamics of optical vortices in van der Waals materials (2023)

Quantized vortices are topological defects found in different two-dimensional geometries, from liquid crystals to ferromagnets, famously involved in spontaneous symmetry breaking and phase transitions. Their optical counterparts appear in planar geometries as a universal wave phenomenon, possessing topologically protected orbital angular momentum (OAM). So far, the spatiotemporal dynamics of optical vortices, including vortex-pair creation and annihilation, has been observed only in Bose–Einstein condensates. Here we observe optical vortices in van der Waals materials and measure their dynamics, including events of pair creation and annihilation. Vortices of opposite OAM are involved in pair creation/annihilation events, and their relative signs determine the surrounding field profile throughout their motion. The vortices are made of phonon polaritons in hexagonal boron nitride, which we directly probe using free electrons in an ultrafast transmission electron microscope. Our findings promote future investigations of vortex phenomena in van der Waals platforms, toward their use for chiral plasmonics, quantum simulators, and control over selection rules in light–matter interactions.
Employing Topological Properties of Phase Singularities for Designing Supercavity Systems with Tailored Excitation (2023)

Abstract Trapping electromagnetic waves in high‐index resonators with extreme quality factors ( Q ‐factor) can be achieved by exciting supercavity (quasi‐bound states in the continuum, quasi‐BIC) modes with minimal radiation loss. Conventionally, the quasi‐BICs are achieved by tuning the resonator dimensions to promote destructive interference between two modes in the cavity. In this work, an enhanced Q ‐factor is achieved by manipulating the structure of a near‐field excitation source and tailoring the excitation strength of individual multipolar modes. A pair of concentric rings with strong mutual coupling is used in contrast to a simple single‐ring case. We show that adding the second passive ring enables additional degrees of freedom to manipulate the multipolar content exited in the cavity. The multipole decomposition of the cavity modes is performed using full‐wave numerical simulations to support these claims. Experimental validation with a double‐ring fed supercavity demonstrates the highest measured Q ‐factor of ≈310 or ≈2× the quality factor of a design without supercavity, which is consistent with a numerical model predicting up to 3× enhanced Q ‐factor. We show that, analyses of polarization singularities and multipolar decomposition can be used to understand, characterize, and design such systems, employing their topological properties not broadly explored before.
Non-aqueous electrolytes for electrochemical cells (2023)

A non-aqueous electrolyte comprising a salt, a non-aqueous solvent, and a compound of Formula (I), (II), or (III), where E is —S(O)— or S(O)2—:
Object Detection as Probabilistic Set Prediction (2022)

Accurate uncertainty estimates are essential for deploying deep object detectors in safety-critical systems. The development and evaluation of probabilistic object detectors have been hindered by shortcomings in existing performance measures, which tend to involve arbitrary thresholds or limit the detector's choice of distributions. In this work, we propose to view object detection as a set prediction task where detectors predict the distribution over the set of objects. Using the negative log-likelihood for random finite sets, we present a proper scoring rule for evaluating and training probabilistic object detectors. The proposed method can be applied to existing probabilistic detectors, is free from thresholds, and enables fair comparison between architectures. Three different types of detectors are evaluated on the COCO dataset. Our results indicate that the training of existing detectors is optimized toward non-probabilistic metrics. We hope to encourage the development of new object detectors that can accurately estimate their own uncertainty. Code available at https://github.com/georghess/pmb-nll.
Grating Light Valves for High-Resolution Displays. (1994)

Abstract : The Grating Light Valve (GLV) is a micromechanical phase grating that can be used for color display applications. Operation is based on electrically controlling the mechanical positions of grating elements to modulate diffraction efficiency. By choosing dimensions of the grating structures carefully, it is possible to produce a digital optical device.
A Paradigm for Blue- or Red-Shifted Absorption of Small Molecules Depending on the Site of π-Extension (2010)

Benzannulation of aromatic molecules is often used to red-shift absorption and emission bands of organic and inorganic, molecular, and polymeric materials; however, in some cases, either red or blue shifts are observed, depending on the site of benzannulation. A series of five platinum(II) complexes of the form (N(∧)N(∧)N)PtCl are reported here that illustrate this phenomenon, where N(∧)N(∧)N represents the tridentate monoanionic ligands 2,5-bis(2-pyridylimino)3,4-diethylpyrrolate (1), 1,3-bis(2-pyridylimino)isoindolate (2), 1,3-bis(2-pyridylimino)benz(f)isoindolate (3), 1,3-bis(2-pyridylimino)benz(e)isoindolate (4), and 1,3-bis(1-isoquinolylimino) isoindolate (5). For this series of molecules, either a blue shift (2 and 3) or a red shift (4 and 5) in absorption and emission maxima, relative to their respective nonbenzannulated compounds, was observed that depends on the site of benzannulation. Experimental data and first principles calculations suggest that a similar HOMO energy level and a destabilized or stabilized LUMO with benzannulation is responsible for the observed trends. A rationale for LUMO stabilization/destabilization is presented using simple molecular orbital theory. This explanation is expanded to describe other molecules with this unusual behavior.
Long-term survival after self-expanding metallic stent or stoma decompression as bridge to surgery in acute malignant large bowel obstruction (2021)

This nationwide registry-based study showed that long-term survival in patients with either SEMS or stoma as bridge to surgery in acute malignant large bowel obstruction were comparable. SEMS were associated with a lower rate of permanent stoma, higher rate of resection surgery and shorter duration of hospital stay.
Stride Scheduling: Deterministic Proportional- Share Resource Management (1995)

This paper presents stride scheduling, a deterministic scheduling technique that efficiently supports the same flexible resource management abstractions introduced by lottery scheduling. Compared to lottery scheduling, stride scheduling achieves significantly improved accuracy over relative throughput rates, with significantly lower response time variability. Stride scheduling implements proportional-share control over processor time and other resources by cross-applying elements of rate-based flow control algorithms designed for networks. We introduce new techniques to support dynamic changes and higher-level resource management abstractions. We also introduce a novel hierarchical stride scheduling algorithm that achieves better throughput accuracy and lower response time variability than prior schemes. Stride scheduling is evaluated using both simulations and prototypes implemented for the Linux kernel. Keywords: dynamic scheduling, proportional-share resource allocation, rate-based...
ICD Trials: An Extraordinary Means of Determining Patient Risk? (1998)

Extensive clinical experience with the implantable cardioverter defibrillator (ICD) combined with recently completed prospective, randomized trials like MADIT and AVID, have demonstrated the lifesaving efficacy of this therapy and its superiority compared to conventional medical management in treating patients at high risk of sudden arrhythmic death. This evidence has in turn spurred great interest in further ICD studies. Since the ability of the ICD to save lives is no longer in question, there is a need to reexamine the real objectives of these new studies.
Fluid-filled underground transmission cable condition assessment (2010)

Many underground power cable users are faced with aging fluid-filled transmission cables that have exceeded their design life of 30-40 years. Major and possibly costly decisions have to be made whether to replace or to continue to use the existing cable system. This paper presents a condition assessment strategy focused on fluid-filled cables that involves a combination of visual observations through on-site inspections, laboratory diagnostics, on-site diagnostics, operation reports and data trending.
Model Compounds Based on Cyclotriphosphazene and Hexaphenylbenzene with Tethered Li+-Solvents and Their Ion-Conducting Properties (2011)

To improve the lithium ion conductivities of currently used electrolytes, it is critical to understand how the transport of the lithium ions within the matrix is influenced by their interactions with solvating moieties. Therefore, well-defined model compounds based on cyclotriphosphazene (CTP) and hexaphenylbenzene (HPB) cores were prepared, bearing side groups containing the structural element of ethylene carbonate, which is the common solvent for lithium salts used as electrolytes in Li-ion batteries. All model compounds were highly pure and thermally stable up to at least 250 °C, covering a broad range of glass transition temperatures from −79 °C up to +3.5 °C. The temperature-dependent ionic conductivities of the blends follow a William−Landel−Ferry (WLF) type behavior with the corresponding glass transition temperatures as reference. Though the glass transition temperatures of the blends are low, their conductivities are only in the range of typical polymer electrolytes, implying that the coordination between the cyclic carbonate functionality and the Li-ion is apparently too tight to allow for fast Li-ion dynamics.
Pilot study of responsive nucleus accumbens deep brain stimulation for loss-of-control eating (2022)

Cravings that precede loss of control (LOC) over food consumption present an opportunity for intervention in patients with the binge eating disorder (BED). In this pilot study, we used responsive deep brain stimulation (DBS) to record nucleus accumbens (NAc) electrophysiology during food cravings preceding LOC eating in two patients with BED and severe obesity (trial registration no. NCT03868670). Increased NAc low-frequency oscillations, prominent during food cravings, were used to guide DBS delivery. Over 6 months, we observed improved self-control of food intake and weight loss. These findings provide early support for restoring inhibitory control with electrophysiologically-guided NAc DBS. Further work with increased sample sizes is required to determine the scalability of this approach.
Structure-Activity Relationships of Adenosine Deaminase Inhibitors (1999)

Abstract Adenosine deaminase (ADA) is an important catabolic enzyme which converts adenosine and deoxyadenosine to inosine and deoxyinosine, respectively. ADA exists in two different isoenzymes, namely ADA1 and ADA2, whose balance in monocytes-macrophages seems to guarantee the homeostasis of adenine nucleosides. Modifications of the purine moiety or/and substitution of the sugar moiety of adenosine with aliphatic chains led to derivatives which are good ADA inhibitors.
New Amidino‐Benzimidazolyl Thiophenes: Synthesis and Photochemical Synthesis. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Interplay between evanescence and disorder in deep subwavelength photonic structures (2016)

Deep subwavelength features are expected to have minimal impact on wave transport. Here we show that in contrast to this common understanding, disorder can have a dramatic effect in a one-dimensional disordered optical system with spatial features a thousand times smaller than the wavelength. We examine a unique regime of Anderson localization where the localization length is shown to scale linearly with the wavelength instead of diverging, because of the role of evanescent waves. In addition, we demonstrate an unusual order of magnitude enhancement of transmission induced due to localization. These results are described for electromagnetic waves, but are directly relevant to other wave systems such as electrons in multi-quantum-well structures.
Photonic crystal nanocavity with a Q-factor of ~9 million (2014)

We have investigated absorption losses due to surface water adsorbed on the surface of silicon heterostructure nanocavities with quality (Q) factors of several million. Measurements performed while changing the ambient humidity that the nanocavity is exposed to show that the Q value depends linearly on humidity. We also reveal that chemical treatment to change the degree of hydrophilicity of the surface results in a drastic increase of Q; we have obtained an experimental value of 9 million, which represents a new record for a heterostructure nanocavity. We analytically determine the absolute value of absorption loss by exploiting the degree of fluctuation of Q values between different samples.
Load–Displacement Characterization in Three Degrees-of-Freedom for General Lamina Emergent Torsion Arrays (2020)

Abstract Lamina emergent torsion (LET) joints for use in origami-based applications enables folding of panels. Placing LET joints in series and parallel (formulating LET arrays) opens the design space to provide for tunable stiffness characteristics in other directions while maintaining the ability to fold. Analytical equations characterizing the elastic load–displacement for general serial–parallel formulations of LET arrays for three degrees-of-freedom are presented: rotation about the desired axis, in-plane rotation, and extension/compression. These equations enable the design of LET arrays for a variety of applications, including origami-based mechanisms. These general equations are verified using finite element analysis, and to show variability of the LET array design space, several verification plots over a range of parameters are provided.
Early treatment of imported falciparum malaria in the intermediate and intensive care unit setting: an 8-year single-center retrospective study (2008)

This retrospective evaluation demonstrated favourable therapeutic results in hospitalized patients with imported falciparum malaria. Both initial treatment in the medical IMC/ICU and close collaboration between intensivists and specialists in tropical medicine may improve disease outcome among affected patients. Prospective studies are needed to confirm these preliminary findings.
Characterization of a Thermostable Enzyme with Phosphomannomutase/Phosphoglucomutase Activities from the Hyperthermophilic Archaeon Pyrococcus horikoshii OT3 (2005)

The phosphomannomutase/phosphoglucomutase (PMM/PGM) enzyme catalyzes reversibly the intra-molecular phosphoryl interconverting reaction of mannose-6-phosphate and mannose-1-phosphate or glucose-6-phosphate and glucose-1-phosphate. Glucose-6-phosphate and glucose-1-phosphate are known to be utilized for energy metabolism and cell surface construction, respectively. PMM/PGM has been isolated from many microorganisms. By performing similarity searches using existing PMM/PGM sequences, the homologous ORFs PH0923 and PH1210 were identified from the genomic data of Pyrococcus horikoshii OT3. Since PH0923 appears to be part of an operon consisting of four carbohydrate metabolic enzymes, PH0923 was selected as the first target for the investigation of PMM/PGM activity in P. horikoshii OT3. The coding region of PH0923 was cloned and the purified recombinant protein was utilized for an examination of its biochemical properties. The enzyme retained half its initial activity after treatment at 95 degrees C for 90 min. Detailed analyses of activities showed that this protein is capable of utilizing a variety of metal ions that are not utilized by previously characterized PMM/PGM proteins. A mutated protein with an alanine residue replacing the active site serine residue indicated that this residue plays an important but non-essential role in PMM/PGM activity.
RF Receiver Characterization and Spurious-Free Dynamic Range Enhancement for PIM/Weakly Nonlinear Device Measurements (2016)

This paper proposes a technique to characterize and postcompensate for the dynamic nonlinearity exhibited by radio frequency (RF) receivers employed in passive intermodulation (PIM) and weakly nonlinear devices characterization (low gain compression of the order of 0.1 dB). The proposed technique begins by accurately characterizing the RF receiver's nonlinearity using two-tone and multitone stimuli with swept frequency spacing and input power level. Then, a pruned Volterra series-based postcompensation model is devised to mitigate the dynamic weak nonlinear distortions exhibited by the receiver. The technique was validated in two steps. First, the capacity of the postcompensation technique to separate the RF receiver's intermodulation from the device under test's intermodulation was assessed. Second, its capacity to postcompensate for the dynamic nonlinearity exhibited by the RF receiver and to enhance its spurious-free dynamic range (SFDR) was assessed using digitally modulated stimuli. The application of the proposed technique reduced the third-order intermodulation (IMD3) of the RF receiver by an average of 10 dB. This technique can significantly relax the requirements on duplexers and tone injection techniques used to enhance the accuracy of PIM measurements. Furthermore, the receiver's SFDR was extended by up to 15 dB.
Realtime Multi-User Multi-Antenna Downlink Measurements (2008)

In this paper, we present real-time broadband multi-user multi-antenna measurements in typical indoor and outdoor scenarios. For the first time, essential frequency-selective functions of a new medium access control (MAC) layer, namely fair resource assignment to multiple users, spatial mode selection and adaptive modulation, have been implemented in real-time on standard digital signal processing hardware. The new MAC layer is steered over wireless feedback and control channels in a closed loop manner. Our implementation uses parameters close to the forthcoming long-term evolution (LTE) of the 3G air interface, thus illustrating the feasibility of the new functions in next-generation cellular radio systems. The paper describes our real-time implementation and reports several test results. Benefits of the frequency-selective multi-user MIMO MAC are validated in realistic mobile propagation environments.
Drosophila parkinmutants have decreased mass and cell size and increased sensitivity to oxygen radical stress (2004)

Mutations in the gene parkin in humans (PARK2) are responsible for a large number of familial cases of autosomal-recessive Parkinson disease. We have isolated a Drosophila homolog of human PARK2 and characterized its expression and null phenotype. parkin null flies have 30% lower mass than wild-type controls which is in part accounted for by a reduced cell size and number. In addition, these flies are infertile, show significantly reduced longevity, and are unable to jump or fly. Rearing mutants on paraquat, which generates toxic free radicals in vivo, causes a further reduction in longevity. Furthermore, loss of parkin results in progressive degeneration of most indirect flight muscle (IFM) groups soon after eclosion, accompanied by apoptosis. However, parkin mutants have normal neuromuscular junction recordings during the third larval instar stage, suggesting that larval musculature is intact and that parkin is required only in pupal and adult muscle. parkin flies do not show an age-dependent dopaminergic neuron loss in the brain, even after aging adults for 3 weeks. Nevertheless, degeneration of IFMs demonstrates the importance of parkin in maintaining specific cell groups, perhaps those with a high-energy demand and the concomitant production of high levels of free radicals. parkin mutants will be a valuable model for future analysis of the mechanisms of cell and tissue degeneration.
Intrinsic performance of carbon-nanotube transistors (2004)

Intrinsic transconductance of carbon-nanotube field-effect transistors (CNTFETs) was investigated with carbon nanotubes (CNTs) grown both by laser ablation and chemical vapor deposition (CVD). The measured transconductance at a drain voltage of -1V was 8.7 /spl mu/S for a CVD-grown CNT with a diameter of 1.5 nm. Very high intrinsic transconductance of 20 /spl mu/S was calculated by considering the contribution of parasitic resistance. Apparent and intrinsic transconductance per unit channel width are considerably larger than those for the state-of-the-art Si-MOSFETs. We expect that the performance of CNTFETs will advance further by improving CNT quality and by optimising device structures.
Charge transport in mesoscopic conducting polymer wires (2008)

In an attempt to reconcile transport in aniline oligomers with that observed in bulk polyaniline, we constructed meso-scale (60 nm) molecular junctions bridged by polyanion-stabilized polyaniline (PANI) strands. Junctions were characterized by their conductance versus electrochemical potential (G-E) and current versus voltage (I-V) characteristics, In contrast to bulk polyaniline, sharp peaks were seen in the G-E data, and these gave rise to negative differential resistance in the I-V curves, behavior much like that observed in aniline oligomers. The width of the conductance peaks increased with the amount of polymer deposited in the junction. In contrast to oligomers, the peaks in the meso-scale devices displayed a large hysteresis. The absolute conductance of the junctions is far too high to be consistent with transport along isolated chains, suggesting that a fundamental charge carrying unit is something morphologically more complex than a single polymer molecule.
Model experiment to study sonic boom propagation through turbulence. Part II. Effect of turbulence intensity and propagation distance through turbulence (1998)

A model experiment was reported to be successful in simulating the propagation of sonic booms through a turbulent atmosphere [B. Lipkens and D. T. Blackstock, J. Acoust. Soc. Am. 103, 148-158 (1998)]. In this study the effect on N wave characteristics of turbulence intensity and propagation distance through turbulence are investigated. The main parameters of interest are the rise time and the peak pressure. The effect of turbulence intensity and propagation distance is to flatten the rise time and peak pressure distributions. Rise time and peak pressure distributions always have positive skewness after propagation through turbulence. Average rise time grows with turbulence intensity and propagation distance. The scattering of rise time data is one-sided, i.e., rise times are almost always increased by turbulence. Average peak pressure decreases slowly with turbulence intensity and propagation distance. For the reported data a threefold increase in average rise time is observed and a maximum decrease of about 20% in average peak pressure. Rise times more than ten times that of the no turbulence value are observed. At most, the maximum peak pressure doubles after propagation through turbulence, and the minimum peak pressure values are about one-half the no-turbulence values. Rounded waveforms are always more common than peaked waveforms.