gebhart/patrepeval huggingface dataset:
Resource allocation for remote desktop sessions in Utility Grids (2005)

Abstract Emerging large‐scale utility computing systems such as Grids promise computing and storage to be provided to end users as a utility. System management services deployed in the middleware are a key to enabling this vision. Utility Grids provide a challenge in terms of scale, dynamism and heterogeneity of resources and workloads. In this paper, we present a model‐based architecture for resource allocation services for Utility Grids. The proposed service is built in the context of interactive remote desktop session workloads and takes application performance QoS models into consideration. The key design guidelines are hierarchical request structure, application performance models, remote desktop session performance models, site admission control, multi‐variable resource assignment system and runtime session admission control. We have also built a simulation framework that can handle mixed batch and remote desktop session requests, and have implemented our proposed resource allocation service into the framework. We present some results from experiments using the framework. Our proposed architecture for resource allocation services addresses the needs of emerging utility computing systems and captures the key concepts and guidelines for building such services in these environments. Copyright © 2005 John Wiley &amp; Sons, Ltd.
Isolation of Lotus edulis bioactive flavonoids (Leguminosae) by Centrifugal Partition Chromatography (2009)

Lotus is a genus of Leguminosae family which is consist of about 100 species which are native in Mediterranean and N. America countries. The specie L. edulis is an annual edible herb which is known in Greece with the common name 'Peratzouni'. The methanolic extract obtained from the aerial part of this plant posses remarkable antioxidant and chemoprotective properties [1]. The photochemical analysis of this extract showed that it is a rich source of Kaempferol glycosides. In order to isolate these flavonoids compounds the Centrifugal Partition Chromatography was used. Twenty one biphasic solvent systems were investigated using TLC and HPLC technique. One of them (Heptane: EtOAc: MeOH: H2O 1:4:1:4) was proved efficient in the separation of five flavonoids. In addition two more Kaempferol derivatives were separated by with another solvent system (EtOAc:n-BuOH: H2O 2:1:2). It is important that all the isolated natural compounds are derivatives of 7-O-ramnopyranosyl kaempferol and their purification by conventional chromatographic methods is very difficult.
Novel and Convenient Synthesis of 2,7-Dialkyl-1,8-dihydro-as-indacenes (2018)

A novel and convenient synthetic route towards dialkyl as-indacenes was achieved by alkylation of malonic esters with o-xylylene dibromide, to give the corresponding tetraester, and related diacid. The alkyl groups on the central benzene ring induce intramolecular, regiospecific cycloeliminations leading selectively to the diketones, the precursors of the corresponding 1,8-dihydro-as-indacenes. The structure of the 2,7-dimethyl-1,8-dihydro-as-indacene was determined by X-ray diffraction. The compound 2,7-diethyl-1,8-dihydro-as-indacene was characterized by means of 1H NMR, 13C NMR, FT-IR, UV/Vis measurements, electrochemistry, and elemental analysis. On the other hand, quantum chemical computations based on DFT methods were carried out to get insight into the molecular and electronic structures of the studied ligands. TDDFT approach was employed to calculate the vertical excitations and characterize the nature the UV/Vis absorption bands present in the experiments showing a very good agreement between experimental and calculated values. Finally, the reactivity of the compounds was assessed using the chemical potential (μ), chemical hardness (η), and electrophilicity (ω). Also, the electron-donating (ω–), electron-accepting (ω+), and the net electrophilicity powers (ω±) indexes were studied.
ChemInform Abstract: General Routes to Functional Organotin Trichlorides and Trialkoxides Involving the Tricyclohexylstannyl Group. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Experience With Heart Transplantation in Children (1987)

Between March 1981 and March 1986, 200 orthotopic heart transplantations were performed at the University of Pittsburgh. Fourteen of those procedures were carried out in children 2 to 16 years of age. Two children received combined liver and heart transplants; one because of familial hypercholesterolemia with associated ischemic heart disease, and the other because of dilated cardiomyopathy associated with intrahepatic biliary atresia. Eight patients had dilated cardiomyopathy, and two had myocarditis. Two had heart transplantations for congenital heart disease: one had multiple muscular ventricular septal defects repaired in infancy and had an associated cardiomyopathy, and the other developed a cardiomyopathic ventricle from a congenital right coronary artery to right atrial fistula. Chronic immune suppression consisted 0.2 to 0.5 mg/kg/d of prednisone and 5 to 50 mg/kg/d cyclosporine, with the addition of antithymocyte globulin for unresolved moderate or severe acute rejection. There were three early postoperative deaths: one from intracranial bleeding, one from Pseudomonas mediastinitis, and one from ischemic injury to transplanted organs. Early postoperative complications included reversible renal failure, hypertension, and seizures. Late problems were related to allograft rejection and side effects of cyclosporine and corticosteroids. Significant rejection episodes occurred in all patients surviving longer than 2 weeks, with seven requiring antithymocyte globulin. Two patients died 8 months following transplantation of severe acute and chronic rejection; another patient required retransplantation for ischemic cardiomyopathy resulting from chronic rejection but subsequently died of recurring rejection 3 months after the second transplantation. Eight surviving patients 4 months to 4 years after heart transplantation had returned to age-appropriate activities. These early results have encouraged the authors to continue to use heart transplantation as a viable alternative in children with terminal heart disease.
MULTI-COMPONENT POLYMER SYSTEMS PROCESSED WITHIN A NARROW TEMPERATURE WINDOW (2008)

The present study deals with model systems based on two immiscible polymers, polypropylene (PP) and copolyamide (PA), containing nano‐size inorganic TiO2, processed in a narrow temperature window, just below the melting temperature of the dispersed copolyamide phase. The blends were compounded using a twin‐screw intermeshing extruder followed by injection molding. The effect of processing temperature and blend composition on morphology, mechanical, rheological and thermal properties of the model systems containing nano‐sized TiO2 and their references were explored. It was found that in‐situ fibrillation of the PA phase occurred in the blends based on PP of a relatively high melt flow index, MFI = 12 g/10 min and higher. The nano‐sized TiO2 particles were located upon and within the PA phase and have slightly influenced the shape of the PA fibrils. A correlation between the processing temperature, morphology and properties of the composites is presented.
World's first 40 Gbps overlay on a field-deployed, 10 Gbps, mixed-fiber, 1200 km, ultra long-haul system (2005)

MCI, Ciena, and Mintera successfully demonstrated the capability of overlaying a production quality 40 Gbps CS-RZ optical signal on a Ciena-designed 1200 km ultra long-haul (ULH) system over an MCI multi-span, mixed-field fiber route from Sacramento to Salt Lake City.
Continuous-flow fast-atom-bombardment liquid chromatography/mass spectrometry of carotenoids (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTContinuous-flow fast-atom-bombardment liquid chromatography/mass spectrometry of carotenoidsRichard B. Van Breemen, Harold H. Schmitz, and Steven J. SchwartzCite this: Anal. Chem. 1993, 65, 8, 965–969Publication Date (Print):April 15, 1993Publication History Published online1 May 2002Published inissue 15 April 1993https://pubs.acs.org/doi/10.1021/ac00056a003https://doi.org/10.1021/ac00056a003research-articleACS PublicationsRequest reuse permissionsArticle Views190Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Magnetomotility of untethered helical soft robots (2019)

Magnetically active helical soft robots were synthesized to achieve efficient tether-less manipulation of the magnetomotility in order to avoid the on-board weight penalty and the distance restrictions originating from connection lines.
Supplementary Figures 1-7 from Loss of Cell-Surface Laminin Anchoring Promotes Tumor Growth and Is Associated with Poor Clinical Outcomes (2023)

&lt;p&gt;PDF file - 1.5MB&lt;/p&gt;
3.7 CHANGES OF INTRINSIC STIFFNESS OF THE CAROTID ARTERIAL WALL DURING THE CARDIAC CYCLE MEASURED BY SHEAR WAVE ELASTOGRAPHY IN HYPERTENSIVES COMPARED TO NORMOTENSIVES (2017)

Objective: Because measurement of arterial stiffness is highly dependent on blood pressure (BP), methods independent of BP are required. Shear wave elastography (SWE, Supersonic Imagine, Aix-en-Provence, France) enables to assess local tissue stiffness by tracking the propagation of shear waves generated into the tissue using ultrafast imaging. This method has never been tested against classical Echotracking (Artlab, Esaote, Maastricht, NL) and carotid to femoral pulse wave velocity (cf-PWV, Sphygmocor, AtCor, Sydney, Australia). Methods: We included 25 subjects, 14 normotensives (NT) and 11 essential hypertensives (HT), matched for age and sex. We optimized SWE algorithms for carotid wall tracking and shear wave group velocity calculation for the anterior (a-SWV) and posterior wall (p-SWV). 8 ultrasonic pushes were triggered at intervals of 200 ms to study the variations of stiffness during the cardiac cycle. Results: p-SWV showed no association with carotid PWV, cf-PWV nor BP. Mean a-SWV over the cardiac cycle was strongly associated with carotid PWV measured by Echotracking (r = 0.56, p = 0.003) and cf·PWV (r = 0.66, p &lt; 0.001). a-SWV strongly increased with BP level during the cardiac cycle (p &lt; 10−6). Similar associations between a-SWV and BP were found in NT and HT although HT had higher values of a-SWV throughout all BP levels. However, when a common BP value (100 mmHg) was considered, no significant difference was found between NT and HT. Conclusion: We have demonstrated with a method independent of BP that the increased arterial stiffness in HT is entirely due to the BP increase. SWE seams a promising technique for assessing arterial stiffness.
Light Energy Dose and Photosensitizer Concentration Are Determinants of Effective Photo-Killing against Caries-Related Biofilms (2020)

Caries-related biofilms and associated complications are significant threats in dentistry, especially when biofilms grow over dental restorations. The inhibition of cariogenic biofilm associated with the onset of carious lesions is crucial for preventing disease recurrence after treatment. This in vitro study defined optimized parameters for using a photosensitizer, toluidine blue O (TBO), activated via a red light-emitting diode (LED)-based wireless device to control the growth of cariogenic biofilms. The effect of TBO concentrations (50, 100, 150, and 200 μg/mL) exposed to light or incubated in the dark was investigated in successive cytotoxicity assays. Then, a mature <i>Streptococcus mutans</i> biofilm model under sucrose challenge was treated with different TBO concentrations (50, 100, and 150 μg/mL), different light energy doses (36, 108, and 180 J/cm<sup>2</sup>), and different incubation times before irradiation (1, 3, and 5 min). The untreated biofilm, irradiation with no TBO, and TBO incubation with no activation represented the controls. After treatments, biofilms were analyzed via <i>S. mutans</i> colony-forming units (CFUs) and live/dead assay. The percentage of cell viability was within the normal range compared to the control when 50 and 100 μg/mL of TBO were used. Increasing the TBO concentration and energy dose was associated with biofilm inhibition (<i>p</i> < 0.001), while increasing incubation time did not contribute to bacterial elimination (<i>p</i> > 0.05). Irradiating the <i>S. mutans</i> biofilm via 100 μg/mL of TBO and ≈180 J/cm<sup>2</sup> energy dose resulted in ≈3-log reduction and a higher amount of dead/compromised <i>S. mutans</i> colonies in live/dead assay compared to the control (<i>p</i> < 0.001). The light energy dose and TBO concentration optimized the bacterial elimination of <i>S. mutans</i> biofilms. These results provide a perspective on the determining parameters for highly effective photo-killing of caries-related biofilms and display the limitations imposed by the toxicity of the antibacterial photodynamic therapy's chemical components. Future studies should support investigations on new approaches to improve or overcome the constraints of opportunities offered by photodynamic inactivation of caries-related biofilms.
Large-Scale Video Analytics through Object-Level Consolidation (2021)

As the number of installed cameras grows, so do the compute resources required to process and analyze all the images captured by these cameras. Video analytics enables new use cases, such as smart cities or autonomous driving. At the same time, it urges service providers to install additional compute resources to cope with the demand while the strict latency requirements push compute towards the end of the network, forming a geographically distributed and heterogeneous set of compute locations, shared and resource-constrained. Such landscape (shared and distributed locations) forces us to design new techniques that can optimize and distribute work among all available locations and, ideally, make compute requirements grow sublinearly with respect to the number of cameras installed. In this paper, we present FoMO (Focus on Moving Objects). This method effectively optimizes multi-camera deployments by preprocessing images for scenes, filtering the empty regions out, and composing regions of interest from multiple cameras into a single image that serves as input for a pre-trained object detection model. Results show that overall system performance can be increased by 8x while accuracy improves 40% as a by-product of the methodology, all using an off-the-shelf pre-trained model with no additional training or fine-tuning.
Influenza virus vector iNS1 expressing bovine papillomavirus 1 (BPV1) antigens efficiently induces tumour regression in equine sarcoid patients (2021)

Bovine papillomaviruses types 1 and 2 (BPV1, BPV2) commonly induce skin tumours termed sarcoids in horses and other equids. Sarcoids seriously compromise the health and welfare of affected individuals due to their propensity to resist treatment and reoccur in a more severe form. We have developed influenza (Flu) A and B virus vectors that harbour a truncated NS1 gene (iNS) assuring interferon induction and co-express shuffled BPV1 E6 and E7 antigens for sarcoid immunotherapy. In a safety trial involving 12 healthy horses, intradermal administration of iNSA/E6E7equ and iNSB/E6E7equ was well tolerated, with the only transient side effect being mild fever in four horses. Repeated screening of secretions and faeces by RT-PCR and plaque assay revealed no virus shedding, thus also confirming biological safety. In a patient trial involving 29 horses bearing BPV1-induced single or multiple sarcoids, at least one lesion per horse was intratumourally injected and then boosted with iNSA/E6E7equ and/or iNSB/E6E7equ. The treatment induced a systemic antitumour response as reflected by the synchronous regression of injected and non-injected lesions. Irrespective of vaccination schemes, complete tumour regression was achieved in 10/29 horses. In 10/29 horses, regression is still ongoing (May 2021). Intriguingly, scrapings collected from former tumour sites in two patients tested negative by BPV1 PCR. Nine severely affected individuals with a history of unsuccessful therapeutic attempts did not (6/29) or only transiently (3/29) respond to the treatment. INSA/E6E7equ and iNSB/E6E7equ proved safe and effective in significantly reducing the tumour burden even in severe cases.
Research on Improving Infrastructure Using New, Untapped, and Recycled Materials (2008)

Research involving new material utilization technology developments, effective never utilized material utilization, recycled aggregate recycling technologies, organic waste materials, and non-construction industrial waste utilization technologies is presented by the authors. Materials discussed include high strength rebar, fiber reinforced polymers, non-standardized aggregates, and reinforced concrete.
In Vivo Validation of a Less Invasive Gastrostimulator (2017)

Gastrointestinal stimulator implants have recently shown promising results in helping obese patients lose weight. However, to place the implant, the patient currently needs to undergo an invasive surgical procedure. We report a less invasive procedure to stimulate the stomach with a gastrostimulator. After attempting fully endoscopic implantation, we more recently focused on a single incision percutaneous procedure. In both cases, the challenges in electronic design of the implant are largely similar. This article covers the work achieved to meet these and details the in vivo validation of a gastrostimulator aimed to be endoscopically placed and anchored to the stomach.
N-linked Glycan Structures and Their Expressions Change in the Blood Sera of Ovarian Cancer Patients (2012)

Glycosylated proteins play important roles in a broad spectrum of biochemical and biological processes, and prior reports have suggested that changes in protein glycosylation occur during cancer initiation and progression. Ovarian cancer (OC) is a fatal malignancy, most commonly diagnosed after the development of metastases. Therefore, early detection of OC is key to improving survival. To this end, specific changes of the serum glycome have been proposed as possible biomarkers for different types of cancers. In this study, we extend this concept to OC. To characterize differences in total N-glycan levels, serum samples provided by 20 healthy control women were compared to those acquired from patients diagnosed with late-stage recurrent OC who were enrolled in an experimental treatment trial prior to receiving therapy (N=19) and one month later, prior to the second treatment cycle (N=11). Additionally, analyses of the N-glycans associated with IgG and characterization of the relative abundance levels of core vs outer-arm fucosylation were also performed. The N-linked glycomic profiles revealed increased abundances of tri- and tetra-branched structures with varying degrees of sialylation and fucosylation and an apparent decrease in the levels of "bisecting" glycans in OC samples compared to controls. Increased levels of a-galactosylation structures were observed on N-linked glycans derived from IgG, which were independent of the presence of fucose residues. Elevated levels of outer-arm fucosylation were also identified in the OC samples. These results allowed the control samples to be distinguished from the baseline ovarian cancer patients prior to receiving the experimental treatment. In some cases, the pre-treatment samples could be distinguished from the post-experimental treatment samples, as many of those patients showed a further progression of the disease.
Changes in casein kinase 2 activity during development of the secondary palate in the hamster (1996)

Background Casein kinase 2 (CK 2) is a serine/threonine kinase that has been ubiquitously conserved in all eukaryotic cells. The exact functions of this enzyme have not yet been clarified; however, studies have repeatedly suggested that it may play crucial roles in the regulation of cell proliferation. During the formation of the secondary palate in the hamster, bursts of cell proliferation occur during the initial half of vertical shelf development, which decrease during the subsequent steps of palate morphogenesis, thus indicating that the cell cycle in the developing vertical palate may be tightly regulated. Methods In the present study, palatal shelves were dissected at 12-hour intervals between days 10 and 12 of gestation, which is the period of vertical shelf development in the hamster. The palates were homogenized and cleared by ultracentrifugation and the resultant supernatants were fractionated on a Mono Q column by fast protein liquid chromatography. Results Using phosvitin as a substrate, the phosphotransferase activity in the fractionated samples decreased steadily from days 10 to 11, increased to a fivefold peak on day 11:12, and then decreased on day 12 of gestation. Western blot analysis using two CK 2 specific antibodies demonstrated that both the 42-kDa (α) and the 38-kDa (α′) subunits of the CK 2 holoenzyme were found throughout the formation of the vertical palatal shelves in the hamster. The amount of α and α′ subunits appears to remain constant, which suggested that the differential activity of the CK 2 enzyme may be due to posttranslational modifications. CK 2 activity correlated well with DNA synthesis (i.e., cell proliferation) rates from days 10 to 11, but not from days 11 to 12 of gestation. Conclusions It is proposed that the activity of CK 2 may regulate the rate of cell proliferation by stimulation of progression through G1 phase of the cell cycle and may also relate to the effects of various growth factors during the vertical development of mammalian palate. © 1996 Wiley-Liss, Inc.