gebhart/patrepeval huggingface dataset:
Bayesian wavelet-domain image modeling using hidden Markov trees (2003)

Wavelet-domain hidden Markov models have proven to be useful tools for statistical signal and image processing. The hidden Markov tree (HMT) model captures the key features of the joint statistics of the wavelet coefficients of real-world data. One potential drawback to the HMT framework is the need for computationally expensive iterative training (using the EM algorithm, for example). In this paper, we propose two reduced-parameter HMT models that capture the general structure of a broad class of grayscale images. The image HMT (iHMT) model leverages the fact that for a large class of images the structure of the HMT is self-similar across scale. This allows us to reduce the complexity of the iHMT to just nine easily trained parameters (independent of the size of the image and the number of wavelet scales). In the universal HMT (uHMT) we take a Bayesian approach and fix these nine parameters. The uHMT requires no training of any kind. While simple, we show using a series of image estimation/denoising experiments that these two new models retain nearly all of the key structures modeled by the full HMT. Based on these new models, we develop a shift-invariant wavelet denoising scheme that outperforms all algorithms in the current literature.
Optimal selection of multicast groups for resource location in a distributed system (1989)

A protocol is presented to locate (or find) named resources in a distributed system which uses the multicast capabilities of the underlying network. Each node in the network uses a sequence of node groups, and each node group is associated with a unique multicast address. To locate a resource, the searching node sequentially polls each one of the groups until the resource is found; this scheme is a generalization of both pure polling and broadcast. To obtain an optimal division of the nodes into multicast groups, the protocol is analyzed and an efficient algorithm is given that provides a group division minimizing the expected cost per location operation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Towards a Fatality-Aware Benchmark of Probabilistic Reaction Prediction in Highly Interactive Driving Scenarios (2018)

Autonomous vehicles should be able to generate accurate probabilistic predictions for uncertain behavior of other road users. Moreover, reactive predictions are necessary in highly interactive driving scenarios to answer "what if I take this action in the future" for autonomous vehicles. There is no existing unified framework to homogenize the problem formulation, representation simplification, and evaluation metric for various prediction methods, such as probabilistic graphical models (PGM), neural networks (NN) and inverse reinforcement learning (IRL). In this paper, we formulate a probabilistic reaction prediction problem, and reveal the relationship between reaction and situation prediction problems. We employ prototype trajectories with designated motion patterns other than "intention" to homogenize the representation so that probabilities corresponding to each trajectory generated by different methods can be evaluated. We also discuss the reasons why "intention" is not suitable to serve as a motion indicator in highly interactive scenarios. We propose to use Brier score as the baseline metric for evaluation. In order to reveal the fatality of the consequences when the predictions are adopted by decision-making and planning, we propose a fatality-aware metric, which is a weighted Brier score based on the criticality of the trajectory pairs of the interacting entities. Conservatism and non-defensiveness are defined from the weighted Brier score to indicate the consequences caused by inaccurate predictions. Modified methods based on PGM, NN and IRL are provided to generate probabilistic reaction predictions in an exemplar scenario of nudging from a highway ramp. The results are evaluated by the baseline and proposed metrics to construct a mini benchmark. Analysis on the properties of each method is also provided by comparing the baseline and proposed metric scores.
Synthesis of novel 3‐ and 5‐substituted indole‐2‐carboxamides (2000)

Abstract The preparation of several novel 3,5‐substituted‐indole‐2‐carboxamides is described. A 5‐nitro‐indole‐2‐carboxylate was elaborated to the 3‐benzhydryl ester, N ‐substituted ester, and carboxylic acid intermedi ates, followed by conversion to the amide and then reduction of the 5‐nitro group to the amine. Indole‐2‐carboxamides with 3‐benzyl and 3‐phenyl substituents were prepared in four steps from either a 3‐bromo indole ester using the Suzuki reaction or from a 3‐keto substituted indole ester. N ‐Alkylation of ethyl indole‐2‐carboxylate, followed by amidation and catalytic addition of 9‐hydroxyxanthene gave a 3‐xanthyl‐indole‐2‐carboxamide analog and a spiropyrrolo indole as a side product.
Widespread intradermal accumulation of mononuclear leukocytes in lepromatous leprosy patients treated systemically with recombinant interferon gamma. (1990)

Intradermal administration of recombinant interferon gamma (rIFN-gamma) to lepromatous leprosy patients has converted the local histology toward a tuberculoid pattern. However, such changes have been confined to the site of injection. In contrast, in the present study, marked, intradermal accumulation of CD3+, CD4+, CD8+, and CD1a+ T cells and Leu-M5+ mononuclear phagocytes was induced at a distance from the sites of administration, in a dose-dependent manner, by 10 daily intramuscular injections of 10-30 micrograms rIFN-gamma/m2. Mononuclear cell infiltration began within 3 d of onset of rIFN-gamma therapy and persisted at least 8 wk. Intramuscular administration of rIFN-gamma to lepromatous patients receiving concurrent chemotherapy can safely induce widespread histologic features of an upgrading reaction.
Prediction of IM240 Mass Emissions Using Portable Exhaust Analyzers. (1996)

Inspection and maintenance programs for motor vehicles in the United States increasingly use loaded mode mass emissions testing (IM240). A method was developed to predict mass emission rates and mass emission changes, particularly from repair benefits, using a low-cost, portable four-gas non-dispersive infrared (NDIR) vehicle exhaust gas analyzer. A single vehicle was tested several times with the analyzer while on the dynamometer and undergoing successive repairs. Excellent correlations for CO and HC were observed. Five vehicles were measured using an on-road driving loop before and after emissions-related repairs, while another three vehicles were tested with no repairs performed. The on-road concentration data used to guide the repair process were converted to grams per gallon; when divided by estimated miles per gallon, this gave grams per mile emissions for comparison to IM240. Correlation coefficients (r<sup>2</sup>) of 0.87 for CO and 0.76 for HC were achieved for the 13 tests. The linear correlations between IM240 and emissions measured by this method would allow repair facilities to perform a relatively inexpensive test for diagnostic purposes and to estimate repair effectiveness without the need for a dynamometer.
Immune phenomena involved in the in vivo regression of fibrosarcoma cells expressing cell-associated IL-1α (2006)

Constitutive expression of cell-associated, but not secreted, interleukin-1alpha (IL-1alpha) by oncogene-transformed fibrosarcoma cells induced regressing tumors in mice, a phenomenon that was abrogated by the IL-1 inhibitor, the IL-1 receptor antagonist (IL-1Ra). On the contrary, non-IL-1alpha-expressing tumor cells induce progressive tumors in mice. In vivo and ex vivo experiments have shown that regression of IL-1alpha-positive fibrosarcoma cells depends on CD8(+) T cells, which can also be activated in CD4(+) T cell-depleted mice, with some contribution of natural killer cells. In spleens of mice bearing the non-IL-1alpha-expressing fibrosarcoma cells, some early and transient manifestations of antitumor-specific immunity, such as activation of specific proliferating T cells, are evident; however, no development of cytolytic T lymphocytes or other antitumor protective cells could be detected. In spleens of mice bearing the non-IL-1alpha-expressing fibrosarcoma cells, the development of early tumor-mediated suppression was observed, and in spleens of mice injected with IL-1alpha-positive fibrosarcoma cells, protective immunity developed in parallel to tumor regression. Treatment of mice bearing violent fibrosarcoma tumors with syngeneic-inactivated, IL-1alpha-positive fibrosarcoma cells, at a critical interval after injection of the malignant cells (Days 5-12), induced tumor regression, possibly by potentiating and amplifying transient antitumor cell immune responses or by ablation of tumor-mediated suppression. Membrane-associated IL-1alpha may thus serve as an adhesion molecule, which allows efficient cell-to-cell interactions between the malignant and immune effector cells that bear IL-1Rs and function as a focused cytokine with adjuvant activities at nontoxic, low levels of expression. Our results also point to the potential of using antitumor immunotherapeutic approaches using cell-associated IL-1alpha.
Identification of the Immunophilins Capable of Mediating Inhibition of Signal Transduction by Cyclosporin A and FK506: Roles of Calcineurin Binding and Cellular Location (1993)

The immunosuppressants cyclosporin A (CsA) and FK506 appear to block T-cell function by inhibiting the calcium-regulated phosphatase calcineurin. While multiple distinct intracellular receptors for these drugs (cyclophilins and FKBPs, collectively immunophilins) have been characterized, the functionally active ones have not been discerned. We found that overexpression of cyclophilin A or B or FKBP12 increased T-cell sensitivity to CsA or FK506, respectively, demonstrating that they are able to mediate the inhibitory effects of their respective immunosuppressants in vivo. In contrast, cyclophilin C, FKBP13, and FKBP25 had no effect. Direct comparison of the Ki of each drug-immunophilin complex for calcineurin in vitro revealed that although calcineurin binding was clearly necessary, it was not sufficient to explain the in vivo activity of the immunophilin. Subcellular localization was shown also to play a role, since gene deletions of cyclophilins B and C which changed their intracellular locations altered their activities significantly. Cyclophilin B has been shown previously to be located within calcium-containing intracellular vesicles; its ability to mediate CsA inhibition implies that certain components of the signal transduction machinery are also spatially restricted within the cell.
An Information Theoretic Analysis of Single Transceiver Passive RFID Networks (2009)

In this paper, we study single transceiver passive RFID networks by modeling the underlying physical system as a special cascade of a certain broadcast channel (BCC) and a multiple access channel (MAC), using a "nested codebook" structure in between. The particular application differentiates this communication setup from an ordinary cascade of a BCC and a MAC, and requires certain structures such as "nested codebooks", impurity channels or additional power constraints. We investigate this problem both for discrete alphabets, where we characterize the achievable rate region, as well as for continuous alphabets with additive Gaussian noise, where we provide the capacity region. Hence, we establish the maximal achievable error free communication rates for this particular problem which constitutes the fundamental limit that is achievable by any TDMA based RFID protocol and the achievable rate region for any RFID protocol for the case of continuous alphabets under additive Gaussian noise.
An Improved Electronic Measurement System for Studying Ingestion and Salivation Activities of Leafhoppers (1981)

Journal Article An Improved Electronic Measurement System for Studying Ingestion and Salivation Activities of Leafhoppers Get access S. Kawabe, S. Kawabe 2Laboratory Applied Entomology, Rice Research Division, Tohoku National Agricultural Experiment Station, Omagari, Akita 014-01 Japan Search for other works by this author on: Oxford Academic Google Scholar D. L. Mclean, D. L. Mclean 3Department of Entomology, University of California, Davis 95616, U.S.A Search for other works by this author on: Oxford Academic Google Scholar S. Tatsuki, S. Tatsuki 4Entomologist and Electrical Engineer, respectively, The Institute of Physical and Chemical Research, Wako-shi, Saitama 351 Japan Search for other works by this author on: Oxford Academic Google Scholar T. Ouchi T. Ouchi 4Entomologist and Electrical Engineer, respectively, The Institute of Physical and Chemical Research, Wako-shi, Saitama 351 Japan Search for other works by this author on: Oxford Academic Google Scholar Annals of the Entomological Society of America, Volume 74, Issue 2, 15 March 1981, Pages 222–225, https://doi.org/10.1093/aesa/74.2.222 Published: 15 March 1981 Article history Received: 02 June 1980 Published: 15 March 1981
ChemInform Abstract: Asymmetric Syntheses of 3‐Amino‐2‐methylpentanoic Acids. Configurations of the β‐Amino Acid in Majusculamide C, 57‐ Normajusculamide C and Dolastatins 11 and 12. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Single-Source Chemical Vapor Deposition of SiC Films in a Large-Scale Low-Pressure CVD Growth, Chemical, and Mechanical Characterization Reactor (2006)

The development and characterization of a silicon carbide deposition process from a single source precursor, 1,3-disilabutane, in a large-scale reactor is described. Deposition was performed simultaneously on fifteen, Si wafers in a 4 or wafer-capable horizontal low-pressure chemical vapor deposition reactor. Amorphous is obtained at temperatures of and below, while some polycrystallinity is obtained at temperatures of and above. Highly uniform and relatively smooth films are realized using a closed wafer boat. A maximum growth rate of is attained at . Residual stress in the film is characterized and found to be greater than (tensile) across a wide range of deposition temperatures. Stress profiling is performed to investigate the stress distribution throughout the films. Microfabrication on the wafer level using as a structural layer is also demonstrated.
HIME: Efficient Headshot Image Super-Resolution with Multiple Exemplars (2023)

A promising direction for recovering the lost information in low-resolution headshot images is utilizing a set of high-resolution exemplars from the same identity. Complementary images in the reference set can improve the generated headshot quality across many different views and poses. However, it is challenging to make the best use of multiple exemplars: the quality and alignment of each exemplar cannot be guaranteed. Using low-quality and mismatched images as references will impair the output results. To overcome these issues, we propose the Headshot Image Super-Resolution with Multiple Exemplars network (HIME) method. Compared with previous methods, our network can effectively handle the misalignment between the input and the reference without requiring facial priors and learn the aggregated reference set representation in an end-to-end manner. Furthermore, to reconstruct more detailed facial features, we propose a correlation loss that provides a rich representation of the local texture in a controllable spatial range. Experimental results demonstrate that the proposed framework not only has significantly fewer computation cost than recent exemplar-guided methods but also achieves better qualitative and quantitative performance.
Photoluminescence and Electroluminescence Characteristics of New Disubstituted Polyacetylenes (2001)

Three di-substituted acetylenes in the tolane structure, 4-(trans-4-pentylcyclohexyl)-3 ′ ,4 ′ -difluorotolane (1M), 4-(trans-4-heptylcyclohexyl)-4 ′ -fluorotolane (2M), and 4-(4-pentylphenyl)-4 ′ -fluorotolane (3M), were polymerized in the presence of TaCl 5 -based catalyst. The weight-average molecular weights \overline Mw of the polymers were high than 4×10 5 . Photoluminescence (PL) and electroluminescence (EL) of the three polymers made as single-layer device on indium-tin oxide glass (ITO), ITO/polymer/Al, have been comprehensively studied. By changing the structural conditions of polymer, such as introducing the fluorine atom or a long carbon chain to the end group of polymer side chains, the luminescence is clearly enhanced.
CD3+ CELLS PERSIST IN THE LIVER OF TRANSPLANTED PATIENTS TREATED WITH OKT3. (1995)

Departments of Anesthesiology and Pathology, University of Florida College of Medicine, Gainesville, FL 32610.
SuperSpec: the on-chip spectrometer: characterization of a full 300 channel filterbank (Conference Presentation) (2018)

SuperSpec is a new technology for millimeter and submillimeter spectroscopy. It is an on-chip spectrometer being developed for multi-object, moderate resolution (R = ~300), large bandwidth survey spectroscopy of high-redshift galaxies for the 1 mm atmospheric window. SuperSpec targets the CO ladder in the redshift range of z = 0 to 4, the [CII] 158 um line from z = 5 to 9, and the [NII] 205 um line from z = 4-7. All together these lines offer complete redshift coverage from z = 0 to 9. SuperSpec employs a novel architecture in which detectors are coupled to a series of resonant filters along a single microwave feedline instead of using dispersive optics. This construction allows for the creation of a full spectrometer occupying only 20 cm squared of silicon, a reduction in size of several orders of magnitude when compared to standard grating spectrometers. This small profile enables the production of future multi-object spectroscopic instruments required as the millimeter-wave spectroscopy field matures. SuperSpec uses a lens-coupled antenna to deliver astrophysical radiation to a microstrip transmission line. The radiation then propagates down this transmission line where upon proximity coupled half wavelength microstrip resonators pick off specific frequencies of radiation. Careful tuning of the proximity of the resonators to the feedline dials in the desired resolving power of the SuperSpec filterbank by tuning the coupling quality factor. The half wavelength resonators are then in turn coupled to the inductive meander of kinetic inductance detectors (KIDs), which serve as the power detectors for the SuperSpec filterbank. Each SuperSpec filter bank contains hundreds of titanium nitride TiN KIDs and the natural multiplexibility of these detectors allow for readout of the large numbers of required detectors. The unique coupling scheme employed by SuperSpec allows for the creation of incredibly low volume (2.6 cubic microns), high responsivity, TiN KIDs. Since responsivity is proportional to the inverse of quasiparticle-occupied volume, this allows SuperSpec to reach the low NEPs required by moderate resolution spectroscopy to be photon limited from the best ground-based observing sites. We will present the latest results from SuperSpec devices. In particular, detector NEPs, measured filter bank efficiency (including transmission line losses), and spectral profiles for a full ~ 300-channel filterbank. Finally, we will report on our system end to end efficiency and total system NEP.
The FNR-like domain of the Escherichia coli sulfite reductase flavoprotein component: crystallization and preliminary X-ray analysis (1998)

The FNR-like domain of the Escherichia coli sulfite reductase flavoprotein subunit was crystallized using the hanging-drop technique, with PEG 4000 as precipitant. The crystals belong to space group P3112 or enantiomorph, with unit-cell parameters a = b = 171.0, c = 152.1 A. A solvent content of 75% was determined by a calibrated tetrachloromethane/toluene gradient which corresponds to three monomers per asymmetric unit. A 3 A resolution native data set was collected at beamline W32 of LURE, Orsay, France.
A 2mW 800MS/s 7th-order discrete-time IIR filter with 400kHz-to-30MHz BW and 100dB stop-band rejection in 65nm CMOS (2013)

Filters are key building blocks in wireless communication and analog signal processing. Typically, Gm-C and active-RC topologies are being used for this purpose. However, reduced supply voltage and lower transistor output impedance make it difficult to implement high-gain wide-bandwidth opamps in a power-efficient manner. Moreover, portable wireless communication devices demand nowadays ever decreasing power consumption, and more tunability/reprogrammability. A discrete-time (DT) analog signal processing approach appears to answer these requirements.
Nursing procedures during continuous renal replacement therapies: a national survey. (2015)

Workload coordination and management of critically ill patients undergoing continuous renal replacement therapies in Italy is not standardized. At present, the duties of critical care and dialysis nurses vary significantly across the country. They frequently overlap or leave gaps in the assistance received by patients. The role of nurses involved in the care of continuous renal replacement therapies patients in Italy currently requires better organization, possibly starting with intensive standardized training and educational programs.
Oligothiophene Phosphonic Acids for Self-Assembled Monolayer Field-Effect Transistors (2021)

Semiconducting self-assembled monolayers (SAMs) represent highly relevant components for the fabrication of organic thin-film electronics because they enable the precise formation of active π-conjugates in terms of orientation and layer thickness. In this work, we demonstrate self-assembled monolayer field-effect transistors (SAMFETs) composed of phosphonic acid oligomers of 3-hexylthiophene (oligothiophenes-OT) with systematic variations of thiophene repeating units (5, 10, and 20). The devices exhibit stable lateral charge transport with increased mobility as a function of thiophene unit counts. Importantly, our work reveals the packing and intermolecular order of varied-chain-length SAMs at the molecular scale via X-ray reflectivity (XRR) and quantitative X-ray photoelectron spectroscopy (XPS). Short oligomers (OT5-PA and OT10-PA) arrange almost perpendicular to the substrate, forming highly ordered SAMs, whereas the long-chain OT20-PA exhibits a folded structure. By tuning the molecular order in the monolayers via the SAM substitution reaction, the OT20-PA devices show a tripling in mobility.
Synthesis and Structural Characterization of Ricin Inhibitors Targeting Ribosome Binding Using Fragment-Based Methods and Structure-Based Design (2021)

Ricin toxin A subunit (RTA) is the catalytic subunit of ricin, which depurinates an adenine from the sarcin/ricin loop in eukaryotic ribosomes. There are no approved inhibitors against ricin. We used a new strategy to disrupt RTA-ribosome interactions by fragment screening using surface plasmon resonance. Here, using a structure-guided approach, we improved the affinity and inhibitory activity of small-molecular-weight lead compounds and obtained improved compounds with over an order of magnitude higher efficiency. Four advanced compounds were characterized by X-ray crystallography. They bind at the RTA-ribosome binding site as the original compound but in a distinctive manner. These inhibitors bind remotely from the catalytic site and cause local conformational changes with no alteration of the catalytic site geometry. Yet they inhibit depurination by ricin holotoxin and inhibit the cytotoxicity of ricin in mammalian cells. They are the first agents that protect against ricin holotoxin by acting directly on RTA.