gebhart/patrepeval huggingface dataset:
Cyclotron Suppression of Pre- and Post-Pulse Radiation from a Relativistic BWO Pulse (2002)

The possibility of using cyclotron interaction to suppress pre‐ and post‐pulse radiation from a relativistic BWO is considered. It is shown that resonant cyclotron absorption, which depends on electron energy, is as able to suppress unacceptable generation as to eliminate reflected signals.
Two‐Phase Catalysis (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Inhibition of CINC-1 Decreases Right Ventricular Damage Caused by Experimental Pulmonary Embolism in Rats (2007)

Right ventricular (RV) dysfunction is a strong risk factor for poor clinical outcome following pulmonary embolism (PE), the third most prevalent cardiovascular disease. Previous studies in our laboratory demonstrated that RV failure during PE is mediated, in part, by neutrophil-dependant cardiac inflammation. In this study we use DNA microarray analysis of gene expression to demonstrate that PE results in increased expression of the CXC chemokines CINC-1 and CINC-2 between 6 and 18 h after the start of PE in a rat model of PE. Neutrophils accumulate in RV tissue by 18 h, and this inflammation is associated with decreased right heart function. Treatment of rats with Abs to CINC-1 significantly suppressed neutrophil accumulation in RVs during PE (52% reduction in tissue myeloperoxidase) and ameliorated RV failure. In addition, plasma concentration of cardiac troponin I, an established diagnostic marker for cardiac damage, was reduced by 90%. These results suggest that selective anti-inflammatory therapies targeted at neutrophil chemoattractants will reduce cardiac inflammation and reduce RV damage in the setting of PE.
Iterative Robust Capon Beamformer (2007)

Many adaptive beamforming algorithms deteriorate drastically in practical applications because they are highly sensitive to mismatches between exploited assumptions and the actual characteristics of the sensor array, environment and sources. Recently, the Robust Capon Beamformer (RCB) is derived which utilizes the uncertainty set of the desired array steering vector and is capable of handling arbitrary array steering vector mismatches. However, when large steering vector mismatches occur, the uncertainty set has to be expanded to accommodate for the increased uncertainty and this degrades the output signal-to-interference-plus-noise ratio (SINR) of the RCB. In this paper, an iterative RCB is proposed which makes use of a small uncertainty sphere to search for the desired array steering vector. This proposed method provides higher SINR than the conventional RCB by avoiding the use of a large uncertainty search sphere. Unlike the conventional RCB, this iterative RCB does not require knowledge of the uncertainty level in the desired array steering vector. Theoretical analysis and computer simulations illustrate the effectiveness of the proposed beamformer.
Hybrid integration of laser source on silicon photonic integrated circuit for low-cost interferometry medical device (2017)

The cost-effective integration of laser sources on Silicon Photonic Integrated Circuits (Si-PICs) is a key challenge to realizing the full potential of on-chip photonic solutions for telecommunication and medical applications. Hybrid integration can offer a route to high-yield solutions, using only known-good laser-chips, and simple freespace micro-optics to transport light from a discrete laser-diode to a grating-coupler on the Si-PIC. In this work, we describe a passively assembled micro-optical bench (MOB) for the hybrid integration of a 1550nm 20MHz linewidth laser-diode on a Si-PIC, developed for an on-chip interferometer based medical device. A dual-lens MOB design minimizes aberrations in the laser spot transported to the standard grating-coupler (15 &mu;m x 12 &mu;m) on the Si-PIC, and facilitates the inclusion of a sub-millimeter latched-garnet optical-isolator. The 20dB suppression from the isolator helps ensure the high-frequency stability of the laser-diode, while the high thermal conductivity of the AlN submount (300/W=m.&deg;C), and the close integration of a micro-bead thermistor, ensure the stable and efficient thermo-electric cooling of the laser-diode, which helps minimise low-frequency drift during the approximately ~ 15s of operation needed for the point-of-care measurement. The dual-lens MOB is compatible with cost-effective passively-aligned mass-production, and can be optimised for alternative PIC-based applications.
Influence of nucleotide identity on ribose 2'-hydroxyl reactivity in RNA (2020)

Hydroxyl-selective electrophiles, including N-methylisatoic anhydride (NMIA) and 1-methyl-7-nitroisatoic anhydride (1M7), are broadly useful for RNA structure analysis because they react preferentially with the ribose 2′-OH group at conformationally unconstrained or flexible nucleotides. Each nucleotide in an RNA has the potential to form an adduct with these reagents to yield a comprehensive, nucleotide-resolution, view of RNA structure. However, it is possible that factors other than local structure modulate reactivity. To evaluate the influence of base identity on the intrinsic reactivity of each nucleotide, we analyze NMIA and 1M7 reactivity using four distinct RNAs, under both native and denaturing conditions. We show that guanosine and adenosine residues have identical intrinsic 2′-hydroxyl reactivities at pH 8.0 and are 1.4 and 1.7 times more reactive than uridine and cytidine, respectively. These subtle, but statistically significant, differences do not impact the ability of selective 2′-hydroxyl acylation analyzed by primer extension-based (SHAPE) methods to establish an RNA secondary structure or monitor RNA folding in solution because base-specific influences are much smaller than the reactivity differences between paired and unpaired nucleotides.
Impact of diagonal correlations on MIMO capacity: application to geometrical scattering models (2003)

The paper highlights the impact of channel correlations on the capacity of MIMO communications, with a focus on the so called diagonal correlations. Based on this analysis, the limitations of simplified mathematical representations, such as the Kronecker or the diagonal-decorrelation models, are pointed out. Finally, the correlation properties of characteristic geometrical scattering models are studied in order to analyze whether these models can be adequately represented by the simplified formalisms, as well as to quantify the errors introduced by these simplifications. With respect to channel correlations, neither the Kronecker model nor the diagonal-decorrelation assumptions are good representations of the investigated geometrical scattering models. When comparing capacity values, it is found that the diagonal-decorrelation model may yield significant errors. In particular, relative errors on ergodic or outage capacity may be significant for the Kronecker model.
Regenerating normal B‐cell precursors during and after treatment of acute lymphoblastic leukaemia: implications for monitoring of minimal residual disease (2000)

We studied 57 childhood acute lymphoblastic leukaemia (ALL) patients who remained in continuous complete remission after treatment according to the Dutch Childhood Leukaemia Study Group ALL-8 protocols. The patients were monitored at 18 time points during and after treatment [640 bone marrow (BM) and 600 blood samples] by use of cytomorphology and immunophenotyping for the expression of TdT, CD34, CD10 and CD19. Additionally, 60 BM follow-up samples from six patients were subjected to clonality assessment via heteroduplex polymerase chain reaction (PCR) analysis of immunoglobulin VH-JH gene rearrangements. We observed substantial expansions of normal precursor B cells in regenerating BM not only after maintenance therapy but also during treatment. At the end of the 2-week intervals after consolidation and reinduction treatment, B-cell-lineage regeneration was observed in BM with a large fraction of immature CD34+/TdT+ B cells. In contrast, in regenerating BM after cessation of maintenance treatment, the more mature CD19+/CD10+ B cells were significantly increased, but the fraction of immature CD34+/TdT+ B cells was essentially smaller. Blood samples showed a profound B-cell lymphopenia during treatment followed by a rapid normalization of blood B cells after treatment, with a substantial CD10+ fraction (10-30%). Heteroduplex PCR analysis confirmed the polyclonal origin of the expanded precursor B cells in regenerating BM. This information regarding the regeneration of BM is essential for the correct interpretation of minimal residual disease studies.
A 45nm SOI monolithic photonics chip-to-chip link with bit-statistics-based resonant microring thermal tuning (2015)

A new thermal tuning circuit for optical ring modulators enables demonstration of an optical chip-to-chip link for the first time with monolithically integrated photonic devices in a commercial 45nm SOI process, without any process changes. The tuning circuit uses independent 1/0 level-tracking and 1/0 bit counting to remain resilient against laser self-heating transients caused by non-DC-balanced transmit data. A 30fJ/bit transmitter and 374fJ/bit receiver with 6μA <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">pk-pk</inf> photocurrent sensitivity complete the 5Gb/s link. The thermal tuner consumes 275fJ/bit and achieves a 600 GHz tuning range with a heater tuning efficiency of 3.8μW/GHz.
A Generic CNN-CRF Model for Semantic Segmentation (2015)

We propose a new CNN-CRF end-to-end learning framework, which is based on joint stochastic optimization with respect to both Convolutional Neural Network (CNN) and Conditional Random Field (CRF) parameters. While stochastic gradient descent is a standard technique for CNN training, it was not used for joint models so far. We show that our learning method is (i) general, i.e. it applies to arbitrary CNN and CRF architectures and potential functions; (ii) scalable, i.e. it has a low memory footprint and straightforwardly parallelizes on GPUs; (iii) easy in implementation. Additionally, the unified CNN-CRF optimization approach simplifies a potential hardware implementation. We empirically evaluate our method on the task of semantic labeling of body parts in depth images and show that it compares favorably to competing techniques.
Loss and Reduction of Fus1 Protein Expression is a Frequent Phenomenon in the Pathogenesis of Lung Cancer (2008)

Our findings show a high frequency of Fus1 protein loss and reduction of expression in lung cancer, and suggests that this reduction may play an important role in the early pathogenesis of lung squamous cell carcinoma. These findings support the concept that FUS1 gene and Fus1 protein abnormalities could be used to develop new strategies for molecular cancer therapy for a significant subset of lung tumors.
A novel regimen for skin survival in composite tissue allotransplantation (2009)

Pulikkottil, Benson J. MD; Jindal, Rishi MD; Unadkat, Jignesh V. MD; Zhang, Dong MD, PhD; Afrooz, Paul N. MD; Zheng, Xin X. MD, PhD; Brandacher, Gerald MD; Petzelbauer, Peter MD; Schneeberger, Stefan MD; Lee, W. P.A. MD Author Information
Progress and prospects for L2-based human papillomavirus vaccines (2016)

Human papillomavirus (HPV) is a worldwide public health problem, particularly in resource-limited countries. Fifteen high-risk genital HPV types are sexually transmitted and cause 5% of all cancers worldwide, primarily cervical, anogenital and oropharyngeal carcinomas. Skin HPV types are generally associated with benign disease, but a subset is linked to non-melanoma skin cancer. Licensed HPV vaccines based on virus-like particles (VLPs) derived from L1 major capsid antigen of key high risk HPVs are effective at preventing these infections but do not cover cutaneous types and are not therapeutic. Vaccines targeting L2 minor capsid antigen, some using capsid display, adjuvant and fusions with early HPV antigens or Toll-like receptor agonists, are in development to fill these gaps. Progress and challenges with L2-based vaccines are summarized.
Notes: Extensional Flow of Linear and Star‐Branched Hydrogenated Polybutadiene with Narrow Molecular Weight Distribution (1981)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation V. S. Au‐Yeung, C. W. Macosko, V. R. Raju; Notes: Extensional Flow of Linear and Star‐Branched Hydrogenated Polybutadiene with Narrow Molecular Weight Distribution. J. Rheol. 1 August 1981; 25 (4): 445–452. https://doi.org/10.1122/1.549649 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentThe Society of RheologyJournal of Rheology Search Advanced Search |Citation Search
Opportunities for Increased Efficiency in Monochromatic Photovoltaic Light Conversion (2018)

We study efficiency loss mechanisms and the potential for improvement of a record-setting monochromatic photovoltaic device, which has demonstrated efficiency of 70% at 830 nm. We combine experimental and modeling-based estimates of losses due to reflection, transmission, thermalization, and series resistance into an extended detailed-balance model that further includes losses due to nonradiative recombination, quantified by an external radiative efficiency (ERE). From the device's efficiency, we estimate ERE ≥ 10%. The device efficiency could be improved by increased material quality, operation at a longer wavelength closer to the GaAs band gap, and increased light intensity. Each order of magnitude increase in incident light intensity or material ERE increases the efficiency by 4% absolute. Redesigning the device to operate at 850 nm reduces thermalization losses by 2% absolute. Overall device efficiency over 80% could be attained by combining these opportunities.
Integrated a-Si:H Source Drivers for 4$^{\prime\prime}$ QVGA Electrophoretic Display on Flexible Stainless Steel Substrate (2007)

Integrated source drivers for a 4'' Quarter Video Graphics Array (QVGA) electrophoretic display have been developed using amorphous silicon TFTs on flexible stainless steel substrate. The current design reduces the number of column interconnects to the display by more than 3times compared to a display with external drivers. This integration reduces cost and improves reliability
Synthesis, X-ray crystal structure, and properties of a tetranuclear complex formed by oxidation of copper(I) chloride with molecular dioxygen in N-methylpyrrolidin-2-one. Isolation of a catalyst for the oxidative coupling of phenols by dioxygen (1978)

G. Davies, M. F. El-Shazly, M. W. Rupich, M. R. Churchill and F. J. Rotella, J. Chem. Soc., Chem. Commun., 1978, 1045 DOI: 10.1039/C39780001045
Surface recombination velocity of highly doped n-type silicon (1996)

New experimental data for the minority-carrier surface recombination velocity of n-type silicon, Sp, are reported. The data, obtained from photoconductance decay measurements of the recombination currents corresponding to different phosphorus diffusions, include oxide-passivated, unpassivated and metal-coated surfaces. For the passivated case, Sp increases linearly with surface dopant density, ND, for dopant densities higher than 1×1018 cm−3, while for unpassivated (bare) and for metal-coated silicon Sp remains essentially constant, at about 2×105 cm/s and 3×106 cm/s, respectively. The experiments also allow for a determination of the apparent energy bandgap narrowing as a function of dopant density, ΔEgapp=14 meV [ln(ND/1.4×1017 cm−3)]. These surface recombination velocity and ΔEgapp data form, together with the dependences of minority-carrier lifetime, τp, and mobility, μp, used in the analysis, a consistent set of parameters that fully characterize highly doped n-type silicon.
Growth and preservation of entanglement in a many-body localized system (2019)

In non-interacting systems disorder leads to Anderson localization, where
particle diffusion and entanglement propagation are absent. Interactions
between the constituent particles modify this picture, leading to a many-body
localized (MBL) phase. A key challenge is to measure interaction induced
dynamics of entanglement between the localized sites in this phase. By studying
interacting photons in an array of superconducting qubits, we observe
ergodicity breaking and directly measure the effective non-local interactions.
We probe the entanglement signatures of MBL in 1D and 2D and observe the slow
growth of entanglement entropy. Finally, we characterize the potential of the
MBL phase to be used as a quantum memory by demonstrating the slow decay of
entanglement of a distant bell pair. Our work elucidates the fundamental
mechanisms of entanglement formation, propagation, and preservation in the MBL
phase of matter.
Keck Diffraction‐limited Imaging of the Young Quadruple Star System HD 98800 (2001)

This paper presents diffraction-limited 1-18 micron images of the young quadruple star system HD 98800 obtained with the W. M. Keck 10-m telescopes using speckle and adaptive optics imaging at near-IR wavelengths and direct imaging at mid-IR wavelengths. The two components of the visual binary, A and B, both themselves spectroscopic binaries, were separable at all wavelengths, allowing us to determine their stellar and circumstellar properties. Combining these observations with spectroscopic data from the literature, we derive an age of 10 Myr, masses of 0.93 and 0.64 M_sun and an inclination angle of 58 deg for the spectroscopic components of HD 98800 B, and an age of 10 Myr and a mass of 1.1 M_sun for HD 98800 Aa. Our data confirm that the large mid-IR excess is entirely associated with HD 98800 B. This excess exhibits a black body temperature of 150 K and a strong 10 micron silicate emission feature. The theoretical equilibrium radius of large, perfectly absorbing, 150 K grains around HD 98800 B is 2.4 AU, suggesting a circum-spectroscopic binary distribution. Our observations set important upper limits on the size of the inner dust radius of ~2 AU (mid-IR data) and on the quantity of scattered light of <10% (H-band data). For an inner radius of 2 AU, the dust distribution must have a height of at least 1 AU to account for the fractional dust luminosity of \~20% L_B. Based on the scattered light limit, the dust grains responsible for the excess emission must have an albedo of <0.33. The presence of the prominent silicate emission feature at 10 microns implies dust grain radii of >2 microns. The total mass of the dust, located in a circumbinary disk around the HD 98800 B, is >0.002 M_earth. The orbital dynamics of the A-B pair are likely responsible for the disk geometry.
ChemInform Abstract: Occurrence of C‐Glucoside of Resveratrol Oligomers in Hopea parviflora (2011)

Abstract isolation and structure elucidation of stereoisomeric hopeasides A and B (I), hopeaside C (II) and D (III)
Tailoring the Pore Sizes of Microporous Pillared Interlayered Clays through Layer Charge Reduction (2012)

A F-rich potassium hectorite, [K(0.48(2))](inter)[Mg(2.54(8))Li(0.43)](oct)[Si(4)](tet)O(10)F(2), with a layer charge of x = 0.48 per formula unit (pfu) was synthesized by high temperature melt synthesis. After Mg-exchange, the layer charge could be reduced significantly post synthesis by annealing (250 °C) as confirmed by alkylammonium exchange and cation exchange capacity. By pillaring this new low charge material with Me(2)DABCO(2+) (N,N-dimethyl-1,1-diazabicyclo [2.2.2]octane dication) and Rh(bpy)(3)(3+) (rhodium-tris-2,2'-bipyridin trication), we observed a remarkable increase in micropore volume and pore diameter by Ar/Ar(l) physisorption measurements. This method allows the tailoring of pore sizes of pillared clays by reducing the layer charge and consequently the pillar density.
Measuring topological invariants in polaritonic lattices (2021)

Thanks to their versatility, photonic systems are very promising platforms for exploring topological physics beyond what is physically reachable in solid-state crystals [1] . In this sense, lattices of semiconductor microcavities confining exciton-polaritons, an hybrid quasi-particle formed from the strong coupling of optical photons and quantum well excitons, offer many advantages. For example, their intrinsic non-hermitian nature allows for probing specific topological properties efficiently and without relying on complex schemes.
New approach to solving crack tip stress fields for piezoelectric materials (2003)

A new technique has been developed which solves the anisotropic stress fields in piezoelectric materials. The technique utilizes orthotropy rescaling by rescaling the coordinate axes in terms of certain elastic, piezoelectric and dielectric material coefficients to obtain the biharmonic equation. The steps which lead to the biharmonic equation require decoupling the stress and electric field components. It is shown that for a certain ratio of dielectric and piezoelectric coefficients, an applied electric field does not change the stress field near a crack tip. The new technique is compared to Stroh's formalism and to finite element modeling.
InnateDB: facilitating systems‐level analyses of the mammalian innate immune response (2008)

Although considerable progress has been made in dissecting the signaling pathways involved in the innate immune response, it is now apparent that this response can no longer be productively thought of in terms of simple linear pathways. InnateDB (www.innatedb.ca) has been developed to facilitate systems-level analyses that will provide better insight into the complex networks of pathways and interactions that govern the innate immune response. InnateDB is a publicly available, manually curated, integrative biology database of the human and mouse molecules, experimentally verified interactions and pathways involved in innate immunity, along with centralized annotation on the broader human and mouse interactomes. To date, more than 3500 innate immunity-relevant interactions have been contextually annotated through the review of 1000 plus publications. Integrated into InnateDB are novel bioinformatics resources, including network visualization software, pathway analysis, orthologous interaction network construction and the ability to overlay user-supplied gene expression data in an intuitively displayed molecular interaction network and pathway context, which will enable biologists without a computational background to explore their data in a more systems-oriented manner.
Stable and Selective Hybridization of Oligonucleotides with Unnatural Hydrophobic Bases (2000)

Relying on only interbase hydrophobic packing for bonding, several unnatural nucleobases similar to 1 can form selective and stable self-pairs in duplex DNA. These unnatural nucleobases should make it possible to increase the stringency and information content of hybridization or encoding experiments.
Orchestration of Wired and Wireless Systems for Future Mobile Transport Network (2020)

In this paper, we present high-speed, low latency, and flexible transport systems for 5G and beyond networks using an orchestration of different transmission mediums, including fiber-optic, free-space optics (FSO), and millimeter-wave (MMW). We introduce the system concepts and review our recent proof-of-concept demonstration results for each system. We also present a hybrid FSO and MMW system for highly resilient and reliable mobile transport in ultra-dense small cell networks.