gebhart/patrepeval huggingface dataset:
Self-induced transparency solitons in a nonlinear Kerr host (1991)

We have found a steady-state solution for a pulse propagating in imhogeneously broadened resonant two-level atoms embedded in a dispersive and nonlinear Kerr lossless host medium. The pulse is of an unchirped hyperbolic-secant form with a linear spatial phase delay. There are several salient features in this solution which are different from the results obtained previously. First, for the given parameters of the medium and carrier frequency, the group velocity, the amplitude, and the pulse width are uniquely determined. Second, the group velocity is independent of the density of the resonant atoms. Third, the solution exists in the positive dispersion region, which is different from solitons in fibers.
Wild-Derived Inbred Mice Have a Novel Basis of Susceptibility to Polyomavirus-Induced Tumors (1999)

Polyomavirus induces a broad array of tumors when introduced into newborn mice of certain standard inbred strains, notably those bearing the H-2(k) haplotype. Susceptibility in these mice is conferred by an endogenous mouse mammary tumor virus superantigen (Mtv-7 sag) that acts to delete T cells required for polyomavirus-induced tumor immunosurveillance. In the present study we show that mice of two wild-derived inbred strains, PERA/Ei (PE) and CZECH II/Ei (CZ), are highly susceptible to polyomavirus but carry no detectable Mtv sag-related sequences and show no evidence of Vbeta deletion. C57BR/cdJ (BR) mice, which are H-2(k) but lack the endogenous Mtv-7, are highly resistant based on an effective anti-polyomavirus tumor immune response. When crossed with BR, both PE and CZ mice transmit their susceptibility in a dominant fashion, indicating a mechanism(s) that overrides the immune response of BR. Susceptibility in PE and CZ mice is not based on interference with antigen processing or presentation since cytotoxic T cells from BR can efficiently kill F(1)-derived tumor cells in vitro. The expected precursors of polyomavirus-specific cytotoxic T cells are present in both the wild inbred animals and their F(1) progeny. These findings indicate a novel basis of susceptibility that operates independently of endogenous superantigen and prevents the development of tumor immunity.
CCECE 2021 Invited Paper: Holistic Performance, Reliability and Thermal Understanding of HPC Real Utilization on Silicon Architecture (2021)

The power density and total power from the package have been increased significantly. The rapid rate of power density increases from one generation to the next not only happens at the device level but also happens at the localized area on the devices. The objective of this study is to build more understanding of the localized high-power density in silicon blocks with respect to the impact in temperature gradient and reliability of the silicon. Conventionally, individual design block power usage numbers are often reported from circuit simulations without considering physical location of transistors and metal wires. However, in a silicon block design, certain transistors may consume significantly more power than others due to higher load capacitance, current draw, frequency, or toggle rate. Therefore, the power distribution is uneven within the design block even in the same use case. In order to gain a better understanding of power density peak spot inside of a single design block, in this study, the transistor activity is dynamically analyzed with circuit simulation vectors of an actual Versal product use case and the spatial power distribution of a 0.5mm x 0.5mm design block is reported in an granularity of 10um x 10um and turn x turn respectively. The analysis results show that the local heat flux can be several magnitudes higher when the design block is analyzed in more granularity. The local heat flux creates local hot spot that was overlooked. The max hotspot temperature would not be captured by the sensor because this specific hotspot sensor location would not be known at first hand due to uncertainty of the exact location created by the local hot spot. Understanding that there can be temperature sensors located some distance(700um) away from hotspot, reporting out the temperature, the device max temperature can be higher than the system monitor readout. Given this max temperature discrepancy, a correlation for max temperature based on heat flux density, source area, heat sink resistance, and senor location would be defined to estimate the max temperature. When the semiconductor chip has hot spots, it affects reliability of the chip. Most of reliability mechanisms result in shorter lifetime with higher temperature and temperature gradients. When a small portion of product has local temperature increase by whatever reason, long-term circuit performance should be altered due to enhanced or reduced aging effect. The device long term reliability is reassessed based on the new discovered localized hot spot.
Time-Resolved Resonance Raman Analysis of Chromophore Structural Changes in the Formation and Decay of Rhodopsin's BSI Intermediate (2002)

Time-resolved resonance Raman microchip flow experiments are performed to obtain the vibrational spectrum of the chromophore in rhodopsin's BSI intermediate and to probe structural changes in the bathorhodopsin-to-BSI and BSI-to-lumirhodopsin transitions. Kinetic Raman spectra from 250 ns to 3 micros identify the key vibrational features of BSI. BSI exhibits relatively intense HOOP modes at 886 and 945 cm(-1) that are assigned to C(14)H and C(11)H=C(12)H A(u) wags, respectively. This result suggests that in the bathorhodopsin-to-BSI transition the highly strained all-trans chromophore has relaxed in the C(10)-C(11)=C(12)-C(13) region, but is still distorted near C(14). The low frequency of the 11,12 A(u) HOOP mode in BSI compared with that of lumirhodopsin and metarhodopsin I indicates weaker coupling between the 11H and 12H wags due to residual distortion of the BSI chromophore near C(11)=C(12). The C=NH(+) stretching mode in BSI at 1653 cm(-1) exhibits a normal deuteriation induced downshift of 23 cm(-1), implying that there is no significant structural rearrangement of the Schiff base counterion region in the transition of bathorhodopsin to BSI. However, a dramatic Schiff base environment change occurs in the BSI-to-lumirhodopsin transition, because the 1638 cm(-1) C=NH(+) stretching mode in lumirhodopsin is unusually low and shifts only 7 cm(-1) in D(2)O, suggesting that it has essentially no H-bonding acceptor. With these data we can for the first time compare and discuss the room temperature resonance Raman vibrational structure of all the key intermediates in visual excitation.
Fast organic circuits on flexible polymeric substrates (2002)

We have fabricated the fastest organic circuits on flexible substrates yet reported. These circuits use the small-molecule hydrocarbon pentacene as the active semiconductor material and 75 /spl mu/m thick flexible, transparent, colorless, polyethylene naphthalate (PEN) film as the substrate. Transistor arrays, inverters, ring oscillators, and other circuits with good electrical performance, yield, and uniformity were obtained. A field-effect mobility of 1 cm/sup 2// V-s was extracted from OTFT saturation characteristics, and ring oscillators had minimum propagation delay <40 /spl mu/sec per stage and <50 /spl mu/sec per stage at bias levels below 8 V.
Calibration and performance validation of optical elements in a photoelastic modulator-based polarimetric camera (2008)

As part of NASA's Instrument Incubator Program (IIP), we have been developing enabling technologies for the Multiangle SpectroPolarimetric Imager (MSPI), a candidate instrument for the Aerosol-Cloud-Ecosytem (ACE) mission. ACE is one of several satellite concepts identified in the 2007 National Research Council Earth Sciences Decadal Survey. MSPI is a multiangle, multispectral, high-accuracy polarization imager, and is envisioned to contain multiple cameras pointed at different viewing angles, with intensity imaging in several spectral bands between the ultraviolet and shortwave infrared, and accurate polarimetric imaging in a subset of the bands. To achieve a degree of linear polarization (DOLP) uncertainty of 1%, we temporally modulate the linear-polarization component of the incoming light at a rapid rate, enabling each detector within a focal-plane array-combined with polarization analyzers-to measure the relative proportions of the linear Stokes components Q or U to the total intensity I. Our system uses tandem photoelastic modulators (PEMs) within a reflective camera design. We report on the status of our prototype camera development, with particular emphasis on theoretical and experimental work on the required and measured performance of optical elements within the system including: the spectropolarimetric filters, quarter wave plates, and tandem PEMs. We also report on the end-to-end measurement and calibration of camera polarization aberrations using a custom polarization state generator (PSG). Careful design and control of scattered light enables the PSG to generate polarization states between DOLP of 0.07% and 40% with an uncertainty of 0.05%, making it a precision tool for polarimetric calibration and validation of MSPI.
Steady-State and Tracking Analysis of the SSLMS Algorithm (2018)

This paper presents expressions for the steady-state mean-square error (MSE), the optimum stepsize, and the corresponding minimum value of the tracking MSE of the sign-sign least mean square (SSLMS) algorithm for the case of real-valued data. Then, simulation results are presented to support our analytical findings and found to corroborate them very well. Also, the performance of the SSLMS algorithm is compared to that of the LMS algorithm in the case where the noise statistics are uniformly distributed.
Flipchip bonding of thin Si dies onto PET foils: Possibilities and applications (2011)

Low cost large area flexible electronic products are expected to be used in a wide range of applications and in large quantities in our society. Examples of this include sensor packages added to food or conformal intelligent patches that monitor a patient's well-being. Because of their large area, the preferred substrate material for these applications will be low cost materials like polyesters (PEN/PET). Intelligence or communicative capabilities are preferably added to these devices by integrating the chips directly on the low cost foil itself. To maintain the flexibility of the package and not to add too much to the thickness, the Si chip needs to be integrated into the product as a bare, thinned die. Flip chip bonding is currently the most mature, widely available technology to integrate these thin chips. The low temperature stability of the PET foils however puts serious constraints on the materials and the process. The current paper specifically addresses the challenges associated with this. Initial results from a finite element model will be discussed. The model is being developed to understand the influence of the bonding process and material parameters on the final stresses and warpage of the chip. Additionally, lifetime and flexural test results will be discussed of ultrathin chips bonded on Cu and Ag-based screen printed circuitry. Finally, some applications of the technology will be shown: a microcontroller integrated on a Cu-PET foil and a supply chain monitoring tag.
Broadband and low ripple double-pumped parametric amplifier and wavelength converter using HNLF (2006)

We report on a double-pumped fiber optical parametric amplifier and wavelength converter with flat gain (35.0 ± 1.5 dB) over 71 nm using a highly non-linear dispersion shifted fiber with low longitudinal variation of the zero dispersion wavelength (&lt; ±0.1 nm).
Metabolic Cytometry: Capillary Electrophoresis with Two-Color Fluorescence Detection for the Simultaneous Study of Two Glycosphingolipid Metabolic Pathways in Single Primary Neurons (2012)

Metabolic cytometry is a form of chemical cytometry wherein metabolic cascades are monitored in single cells. We report the first example of metabolic cytometry where two different metabolic pathways are simultaneously monitored. Glycolipid catabolism in primary rat cerebella neurons was probed by incubation with tetramethylrhodamine-labeled GM1 (GM1-TMR). Simultaneously, both catabolism and anabolism were probed by coincubation with BODIPY-FL labeled LacCer (LacCer-BODIPY-FL). In a metabolic cytometry experiment, single cells were incubated with substrate, washed, aspirated into a capillary, and lysed. The components were separated by capillary electrophoresis equipped with a two-spectral channel laser-induced fluorescence detector. One channel monitored fluorescence generated by the metabolic products produced from GM1-TMR and the other monitored the metabolic products produced from LacCer-BODIPY-FL. The metabolic products were identified by comparison with the mobility of a set of standards. The detection system produced at least 6 orders of magnitude dynamic range in each spectral channel with negligible spectral crosstalk. Detection limits were 1 zmol for BODIPY-FL and 500 ymol for tetramethylrhodamine standard solutions.
Privacy preserving node selection: A physical layer approach (2015)

Distributed monitoring and sensing networks are ubiquitous in current technological systems. Security and efficiency of the data aggregation and fusion process are key determinants in the adoption of these systems. The principal thesis investigated in this paper is the role of privacy in providing security guarantees for such networks. We demonstrate that two-level hierarchy (or partition) in information fusion networks can be used to ensure security in several adversarial scenarios. We propose a privacy preserving physical layer framework to generate such a hierarchical structure. We illustrate the security of this framework and its application to low power sensor networks.
Principal Component Analysis of Multi Spectral Data for Near Real Time Skin Chromophore Mapping (2010)

Abstract not provided
Development of a new solvent extraction process based on butyl-1-[N,N-bis(2-ethylhexyl)carbamoyl]nonyl phosphonic acid for the selective recovery of uranium(VI) from phosphoric acid (2016)

The promising new extractant molecule butyl-1-[N,N-bis(2-ethylhexyl)carbamoyl]nonyl phosphonic acid (DEHCNPB) was designed and used to develop a new solvent extraction process for the selective recovery of uranium from phosphoric acid. This bifunctional extracting molecule shows high affinity and selectivity for uranium(VI) versus iron(III) and the other elements present in phosphoric acid (Al, Ti, V, etc.). Batch equilibrium experiments were first carried out to determine the stoichiometries of the different complexes formed with uranium(VI) and iron(III) in organic phase and to optimize the different steps of the process at laboratory scale. These experimental data were then used to develop a chemical model to simulate uranium(VI) and iron(III) extraction from phosphoric acid, which was implemented in the PAREX simulation code. A flowsheet was calculated and tested in laboratory-scale mixer-settlers on a genuine phosphoric acid industrial solution. The continuous counter-current test was very successful and showed the possibility to recover more than 95% of uranium decontaminated from the main impurities. A Fe/U ratio of 0.03% was measured in the uranium product, which confirms the high potential of this new solvent for the further production of nuclear-grade uranium from phosphate ores.
A Framework for Inference Using Goodness of Fit Tests Based on Ensemble of Phi-Divergences (2012)

In this paper we study the inferential use of goodness of fit tests in a non-parametric setting. The utility of such tests will be demonstrated for the test case of spectrum sensing applications in cognitive radios. We provide the first comprehensive framework for decision fusion of an ensemble of goodness-of-fit testing procedures through an Ensemble Goodness-of-Fit test. Also, we introduce a generalized family of functionals and kernels called Φ-divergences which allow us to formulate goodness-of-fit tests that are parameterized by a single parameter. The performance of these tests is simulated under Gaussian and non-Gaussian noise in a MIMO setting. We show that under uncertainty in the noise statistics or non-Gaussianity in the noise, the performance of non-parametric tests in general, and phi-divergence based goodness-of-fit tests in particular, is significantly superior to that of the energy detector with reduced implementation complexity. In particular, the false alarm rates of our proposed tests is maintained at a fixed level over a wide variation in the channel noise distributions. Additionally, we describe a collaborative spatially separated version of the test for robust combining of tests in a distributed spectrum sensing setting and quantify the significant collaboration gains achieved.
CUGBP2 downregulation by prostaglandin E2protects colon cancer cells from radiation-induced mitotic catastrophe (2008)

Prostaglandin E(2) (PGE(2)) is a potent inhibitor of ionizing radiation (IR)-induced cell death. Exposure of colon cancer cells to IR leads to increased CUGBP2 expression. Therefore, we tested the hypothesis that PGE(2) radioprotects colon cancer cells by inhibiting CUGBP2 expression. Exposure of HCT-116 cells to gamma-IR (0-12 Gy) resulted in a dose-dependent reduction in cell growth and an increase in the G(2)-M phase of the cell cycle. Western blot analyses demonstrated increased levels of activated caspase 9 and caspase 3. In addition, whereas Bax expression is increased, that of Bcl-2 and Bcl-x(L) was reduced. Further analyses demonstrated increased activation of Chk1 and Chk2 kinases, coupled with higher levels of nuclear cyclin B1 and Cdc2. Pretreatment with PGE(2) suppressed the activation of caspase 3 and caspase 7 and inhibited Bax expression. In addition, PGE(2) treatment restored growth and colony formation to control levels. IR significantly upregulated the expression of CUGBP2 in the cells, which was suppressed when cells were pretreated with PGE(2). Ectopic overexpression of CUGBP2 also induced apoptosis. Furthermore, it reversed the PGE(2)-mediated protection from IR-induced mitotic catastrophe. Furthermore, there was an increase in nuclear localization of cyclin B1 and Cdc2 coupled with increased phosphorylation of p53, Chk1, Chk2, and Cdc25c proteins. Cell cycle analysis also demonstrated increased G(2)-M transition. In contrast, siRNA-mediated suppression of CUGBP2 expression restored normal cell cycle progression and decreased IR-induced apoptosis. Taken together, these data demonstrate that PGE(2) protects colon cancer cells from IR-induced mitotic catastrophe in part through suppression of CUGBP2 expression.
Improved light extraction from white organic light-emitting devices using a binary random phase array (2014)

We have developed a binary random phase array (BRPA) to improve the light extraction performance of white organic light-emitting devices (WOLEDs). We demonstrated that the scattering of incoming light can be controlled by employing diffraction optics to modify the structural parameters of the BRPA. Applying a BRPA to the substrate of the WOLED leads to enhanced extraction efficiency and suppression of angle-dependent color changes. Our systematic study clarifies the effect of scattering on the light extraction of WOLEDs.
Activation of kinin B1 receptors induces chemotaxis of human neutrophils (2006)

Kinins are biologically active peptides that are powerful mediators of cellular inflammation. They mimic the cardinal signs of inflammation by inducing vasodilatation and by increasing vascular permeability and pain. Neutrophils are chemoattracted to sites of inflammation by several stimuli. However, the evidence concerning the chemotactic effect of kinin peptides has been contradictory. We analyzed the chemotactic effect of kinin B(1) receptor agonists on neutrophils isolated from peripheral blood of human healthy subjects. Chemotaxis was performed using the migration under agarose technique. To test the effect of B(1) receptor agonists, each assay was carried out overnight at 37 degrees C in 5% CO(2)-95% air on neutrophils primed with 1 ng/ml interleukin-1beta. Simultaneous experiments were performed using unprimed cells or cells challenged with formyl-Met-Leu-Phe (fMLP). A clear chemotactic activity was observed when primed neutrophils were challenged with Lys-des[Arg(9)]-bradykinin (LDBK) or des[Arg(9)]-bradykinin at 10(-10) M but not when unprimed cells were used. A reduction in the chemotactic response was observed after priming of cells in the presence of 0.5 mM cycloheximide and 10 mug/ml brefeldin A, suggesting that some protein biosynthesis is required. Techniques such as reverse transcriptase-polymerase chain reaction and in situ hybridization confirmed the expression of the B(1) receptor mRNA, and immunocytochemistry and autoradiography demonstrated the expression of the B(1) receptor protein. In contrast to other chemoattractants such as fMLP, cytosolic intracellular calcium did not increase in response to the B(1) receptor agonist LDBK. A generation of kinin B(1) receptor agonists during the early phase of acute inflammation may favor the recruitment of neutrophils to the inflammatory site.
TermMerg: An Efficient Terminal-Reduction Method for Interconnect Circuits (2007)

In this paper, a novel method to efficiently reduce the terminal number of general linear-interconnect circuits with a large number of input or output terminals considering delay uncertainty is proposed. Our new algorithm is motivated by the fact that terminal reduction can lead to a more compact order-reduced model and the observation that very large-scale integration interconnect circuits have many similar terminals in terms of their timing and delay metrics due to their closeness in structure or due to the mathematical discretization using meshing in finite-difference or finite-element scheme during the extraction process. The new method, called TermMerg ( Proc. ICCAD, p. 821, 2005), is based on the moments of the circuits as the metrics for the timing or delay. It then employs a singular-value-decomposition (SVD) method to determine the best number of clusters based on the low-rank approximation. After this, the -means clustering algorithm is used to cluster the moments of the terminals into the different clusters. The proposed method can work with any passive-model order reduction and ensure the passive models. In contrast, we show that singular value decomposition model order reduction (SVDMOR) does not generate passive models in general. Passivity enforcement in SVDMOR will significantly hamper the terminal-reduction effectiveness. Experimental results on a number of real industry interconnect circuits demonstrate the effectiveness of the proposed method and show also that the proposed method is more accurate than SVDMOR when the used moment matrix does not give good terminal correlations.
White OLEDs for Displays and General Lighting (2019)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text J. Kido and T. Chiba, "White OLEDs for Displays and General Lighting," in OSA Advanced Photonics Congress (AP) 2019 (IPR, Networks, NOMA, SPPCom, PVLED), OSA Technical Digest (Optica Publishing Group, 2019), paper PW1C.1. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article