gebhart/patrepeval huggingface dataset:
ChemInform Abstract: Tetrahydrofuran Amino Acids: Secondary Structure in Tetrameric and Octameric Carbopeptoids Derived from a D‐allo 5‐(Aminomethyl)tetrahydrofuran‐2‐carboxylic Acid. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Storage Conditions of Human Kidney Tissue Sections Affect Spatial Lipidomics Analysis Reproducibility (2020)

Lipids often are labile, unstable, and tend to degrade overtime, so it is of the upmost importance to study these molecules in their most native state. We sought to understand the optimal storage conditions for spatial lipidomic analysis of human kidney tissue sections. Specifically, we evaluated human kidney tissue sections on several different days throughout the span of a week using our established protocol for elucidating lipids using high mass resolution matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI). We studied kidney tissue sections stored under five different conditions: open stored at -80 °C, vacuumed sealed and stored at -80 °C, with matrix preapplied before storage at -80 °C, under a nitrogen atmosphere and stored at -80 °C, and at room temperature in a desiccator. Results were compared to data obtained from kidney tissue sections that were prepared and analyzed immediately after cryosectioning. Data was processed using METASPACE. After a week of storage, the sections stored at room temperature showed the largest amount of lipid degradation, while sections stored under nitrogen and at -80 °C retained the greatest number of overlapping annotations in relation to freshly cut tissue. Overall, we found that molecular degradation of the tissue sections was unavoidable over time, regardless of storage conditions, but storing tissue sections in an inert gas at low temperatures can curtail molecular degradation within tissue sections.
Molecular alterations in gastric cancer: the role of Helicobacter pylori (2000)

Helicobacter pylori has been classified as a human carcinogen contributing to the pathogenesis of gastric cancer. Extensive sero-epidemiological studies and recently animal experiments have established a close link between H. pylori infection and the development of gastric cancer. However, the molecular changes induced by H. pylori directly or the concomitant chronic inflammation of the gastric mucosa, and the impact of these changes on the subsequent development of gastric cancer, remain largely unknown. This review will highlight the present knowledge on the molecular pathogenesis of gastric cancer with an emphasis on molecular and genetic alterations which develop due to chronic infection of the gastric mucosa by H. pylori.
Molecular Dynamics in Confined Space (2003)

Introduction Ethylene Glycol in Zeolites Propylene Glycol in Mesoporous MCMs Poly(Vinyl Ether) in Mesoporous MCMs Conclusions References
Leveraging attention scarcity to improve the overall user experience of Cloud services (2013)

Applications for mobile devices are increasingly relying on Cloud services to provide content and offload data processing tasks. Traditionally, web-based systems have been optimised to improve response time. Touch sensitive screens and the various sensors of mobile devices allow for better instrumentation, enabling providers to obtain more honest signals on how users utilise a service and learn about their behaviours. This work introduces an architecture that explores honest signals to determine a few user behaviours, e.g. the tendency to perform multiple tasks at a time, change focus, and expect fast response from a service. The architecture relies on a novel resource management strategy that considers such behaviours to prioritise service requests from users who demand fast response from a service. By comparing the proposed strategy with one that does not consider the signals, we show that the experience of users who demand faster response time can be improved without degrading the quality of service of those who often perform multiple activities. The proposed strategy also brings benefits to service providers as no additional resources are necessary to enhance overall user experience, which we modelled using Prospect Theory.
Terahertz Radiation from Strongly Correlated Electron Systems and Related Phenomena. (2002)

We review the study on terahertz (THz) beam generation from strongly correlated electron systems; Pr0.7Ca0.3MnO3(PCMO), Tl2Ba2CaCu2O8+δ (Tl2212), and Bi2Sr2CaCu2O8+δ (Bi2212) thin films. Remarkable difference in thier emission properties and those from semiconductors or YBa2Cu3O7-δ (YBCO) is observed. The ultrafast carrier dynamics in the optically excited YBCO thin films is also discussed on the basis of its THz emission properties. Furhtermore, we report new results on the THz time domain spectroscopic studies of PCMO, La0.7Ca0.3MnO3, Bi2212, and SrBi2Ta2O9 thin films.
The Etiologic Basis of Congestive Heart Failure (2005)

Appropriate management of congestive heart failure requires recognition of the underlying etiologic basis. Currently, sequelae of ischemic heart disease are the most common causes of congestive heart failure in the United States. Mechanical causes of heart failure, which include coronary artery, valvular, and pericardial disease, must be diagnosed correctly in order to offer appropriate surgical therapy. Primary diseases of the myocardium, ie,cardiomyopathies, account for approximately 20% of cases of congestive heart failure [1]. Many systemic diseases, such as rheumatologic disorders, metabolic derangements, toxin exposures, and endocrinopathies, may affect cardiac function and present as a cardiomyopathy [2]. Although these secondary cardiomyopathies are rare, taken together they represent a significant proportion of new cases of dilated cardiomyopathy. As with mechanical causes, recognition of secondary cardiomyopathies is essential because treatment may result in the reversal of cardiac dysfunction.
Spectroscopic, optical and thermo-mechanical properties of GSGG and its laser performance (1986)

Spectroscopic, optical, and thermo‐mechanical properties central to the design of high average power Nd:Cr:GSGG lasers are presented. The status of crystal growth and achieved laser performance levels are briefly reviewed.
Progressive loss of PAX9 expression correlates with increasing malignancy of dysplastic and cancerous epithelium of the human oesophagus (2002)

Pax genes encode a family of transcription factors that play key roles in embryonic development. Whereas the functions of Pax genes in the adult organism are largely unknown, upregulated Pax gene expression has been implicated in tumourigenesis. In this study, PAX9-specific monoclonal antibodies have been generated and it has been shown that PAX9 protein is expressed in the normal epithelium of the adult human oesophagus. PAX9 expression was either lost or significantly reduced in the majority of invasive carcinomas and epithelial dysplasias, the latter representing precancerous lesions. Notably, the percentage of PAX9-positive cells within the epithelium decreased with increasing malignancy of the epithelial lesion. These results identify PAX9 as a sensitive marker for deregulated differentiation of oesophageal keratinocytes and indicate a role for PAX9 in the normal differentiation process of internal stratified squamous epithelia. These data suggest that upregulated PAX9 expression is not required for the formation of the majority of squamous cell carcinomas of the human oesophagus.
ChemInform Abstract: Conversion of 1,3‐Thiazolidines to Dihydro‐1,4‐thiazines by Chlorinolysis. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Infection and inflammation does not effect ventilation distribution in infants with cystic fibrosis (CF) (2011)

Introduction: Preschool and school aged children with CF have been reported to show an elevated lung clearance index (LCI), which further increases in the presence of Pseudomonas aeruginosa infection. In contrast, increased LCI is less prevalent in infants with CF. The aim of this study was to assess the impact of pulmonary infection and the presence of free neutrophil elastase (NE) as a marker of airway inflammation, on ventilation distribution in infants and children ≤ 2 years with CF. Methods: Multiple breath washout (MBW) using 5% SF 6 and an ultrasonic flowmeter (Ecomedics, Switzerland) was performed 1-3 days prior to bronchoalveolar lavage (BAL) in 85 children. LCI and the 1st and 2nd moment ratio (M1/M0 and M2/M0) were determined from the washout. Generalised estimating equations with exchangeable working correlation structure were used to estimate linear regression coefficients. Adjustments were made for sex, height and functional residual capacity. Results: The presence of a pulmonary infection (n=13; ≥10 5 cfu.ml -1 ) had no impact on LCI (p=0.353), but did result in increased M1/M0 (p=0.027) and M2/M0 (p=0.052) when compared to un-infected infants (n=36). Children with P. aeruginosa (n=4) colonisation showed no altered MBW outcomes when compared to the un-infected group. Similarly, the presence of NE (n=14) was not associated with altered MBW outcomes. Conclusion: LCI in this group of children was not a sensitive measure of CF lung disease as indicated by free NE or endobronchial infection. Moment ratios appear to be more sensitive to lung disease associated with infection than LCI.
Vibration identification over 50km SSMF with Pol-Mux coded phase-OTDR (2019)

International audience
Power enhancement for argon II narrow tube lasers by a transverse magnetic field (1985)

Appreciable enhancement in output and power efficiency for compact Ar II lasers (488.0 nm) is obtained by applying a transverse magnetic flux density at approximately 700 G. The enhancement factor amounts to as large as 3 in laser output and the efficiency becomes more than twice as much as without magnetic flux. A sharp rise in output occurs above the critical magnetic flux density, 450 G in the present work, where the cyclotron radius of electrons is nearly equal to one-half of the tube radius.
Qin notation generator (2005)

A Chinese character is a two-dimensional typological representation of strokes and radicals. This is unlike English letters, where there are only 26 letters which combine in one dimension. As there are thousands of Chinese characters, any Chinese character font requires more space (typically two bytes) for its computer encoding. Additionally, it takes more time for the creation of a complete font set. Another problem is web communication. If a character is not available from the client’s font set, there is no clean way to put the information in the web document. This is what originally motivated us to work on dynamic character generation. The Qin is a Chinese musical instrument with a music specification language that serves as a good example of Chinese character stroke and radical combinations. The notation which represents the music is made with a set of characters and radicals. People who show Qin notation on the web have to scan an image and put it on the web. This project attempts to use Qin notation generation to demonstrate the possibility of Chinese character rendering. This project is divided into two parts: the first is the Qin notation description language, and the second is the web notation generator. The description language will be based on Hanglyph, which is a syntax able to describe the hierarchical structure of Chinese characters. The Qin description language will use the basic characters and components. The rendering will construct the notation using MetaPost, based on Hanglyph. A web generator will output the pages with the Qin notation to allow communication over the internet.
Volume holographic narrow-band optical filter: erratum (1993)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text George A. Rakuljic and Victor Leyva, "Volume holographic narrow-band optical filter: erratum," Opt. Lett. 18, 753-753 (1993) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Localization of the simian virus 40 small t antigen in the nucleus and cytoplasm of monkey and mouse cells (1984)

Monkey and mouse cells producing simian virus 40 small t antigen in the absence of clearly detectable intact or truncated large T antigens were subjected to indirect immunofluorescence and biochemical cell compartment analyses. Results revealed specific immunofluorescence and small t polypeptide in both the nucleus and cytoplasm of these cells.
ChemInform Abstract: Selective N‐Functionalization of 6‐Substituted‐2‐pyridones. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Improving output current distortion in hybrid BCM current controlled three-phase micro-inverter (2013)

Hybrid boundary conduction mode (BCM) current controlled inverters have an ability to achieve high efficiency and high power density. Due to easy digital implementation and no requirement of additional components this current control method is very promising for low power applications such as three-phase micro-inverters. However, some practical aspects of its implementation such as dead-time insertion can degrade the performance of the micro-inverter. This paper presents a dead-time compensation method that improves the performance of hybrid BCM current control by decreasing the output current THD and reducing the zero crossing distortion. A brief analysis of hybrid soft switched BCM inverter is given in the paper. The proposed method has been implemented for a 400W 208VAC three-phase prototype. The experimental results show that the output current THD is reduced to 2.5% and thus satisfies the THD requirements under different load conditions.
Effects of the Molecular Weight of Hyaluronic Acid in a Carbon Nanotube Drug Delivery Conjugate (2020)

Hyaluronic acid (HA) is a ubiquitous biopolymer involved in many pathophysiological roles. One HA receptor, the cluster of differentiation CD44 protein, is often overexpressed in tumor cells. As such, HA has attracted considerable interest in the development of drug delivery formulations, given its intrinsic targetability toward CD44 overexpressing cells. The present study is focused on examining the correlation of HA molecular weight with its targetability properties. A library of conjugates obtained by linking the amino group of the phospholipid 1,2-dimyristoyl-<i>sn</i>-glycero-3-phosphoethanolamine (DMPE) to the carboxylic residues of HA of different molecular weight (6.4, 17, 51, 200, and 1,500 kDa) were synthesized and fully characterized. The HA-DMPE conjugates were then used to non-covalently functionalize the highly hydrophobic single-walled carbon nanotubes (CNT), and further encapsulate the anticancer drug doxorubicin (DOX). Our results show that the complexes DOX/CNT/HA-DMPE maintain very good and stable dispersibility. Drug release studies indicated a pH-responsive release of the drug from the nanocarrier. Cell viability tests demonstrated that all HA modified CNTs have good biocompatibility, and specific targeting toward cells overexpressing the CD44 receptor. Among all the molecular weights tested, the 200 kDa HA showed the highest increase in cellular uptake and cytotoxic activity. All these promising attributes make CNT/HA<sub>200</sub>-DMPE a "smart" platform for tumor-targeted delivery of anticancer agents.
Procalitonin: A prognosis factor in lung cancer and a marker for small-cell lung cancer (2011)

Introduction: Serum procalcitonin (PCT) is used for the early diagnosis of bacterial infections. PCT is also a prognostic factor in thyroid carcinomas and PCT level is also usually increased in small cell lung cancer. Aim: To evaluate the serum PCT level as a diagnostic and prognostic marker of lung cancer Methods: Sera sampled between December 2008 and November 2010 for neuron-specific enolase (NSE) dosage at the Rouen University Hospital were retrieved. A PCT dosage was performed on samples from untreated patients with histologically proven lung cancer. Results: From the 147 blood samples selected, 66 came from adenocarcinoma patients, 58 from neuroendocrine lung cancers (NELC) including 51 small cell lung cancers, 6 large cell lung cancers and one atypical carcinoid, 21 from squamous cell carcinomas and 2 sarcomas. Median serum PCT level was higher in NELC (0.35 ng/ml, [0.11-1.23]) as compared to adecarcinoma (0.08; [0.05-0.14]), or squamous cell carcinoma (0.1; [0.06-0.19]) In univariate analysis, patients with a PCT >0.15 ng/ml had a lower median survival than patients with a PCT Conclusion: Serum PCT should not be used for the early diagnosis of bacterial infection in patients with a NELC. Elevated PCT appears to be a marker of poor prognosis in lung cancer patients.
Complex Concrete Constructions – Merging Existing Casting Techniques with Digital Fabrication (2013)

In the course of the 20th century, architectural construction has gone through intense innovation in its material, engineering and design, radically transforming the way buildings were and are conceived. Technological and industrial advances enabled and challenged architects, engineers and constructors to build increasingly complex architectural structures from concrete. Computer-Aided Design and Manufacturing (CAD/CAM) techniques have, more recently, rejuvenated and increased the possibilities of realising ever more complex geometries. Reinforced concrete is often chosen for such structures since almost any shape can be achieve when poured into a formwork. However, designs generated with digital tools tend to have limited relation to the efficient modes of production typically used in contemporary concrete construction. A large gap has emerged between the technology in architectural design and the building industry, so that few efficient solutions exist for the production of geometrically complex structures in concrete. This paper focuses on the capabilities and efficiency of existing casting techniques both with static and dynamic formwork which, when combined with digital fabrication, allow innovative fabrication approaches to be taken. Particular focus is placed on slipforming, an approved and efficient construction technique, which until now is unexplored in conjunction with digital fabrication.Â
Structural Basis for the Identification of an i‐Motif Tetraplex Core with a Parallel‐Duplex Junction as a Structural Motif in CCG Triplet Repeats (2014)

Abstract CCG triplet repeats can fold into tetraplex structures, which are associated with the expansion of (CCG) n trinucleotide sequences in certain neurological diseases. These structures are stabilized by intertwining i‐motifs. However, the structural basis for tetraplex i‐motif formation in CCG triplet repeats remains largely unknown. We report the first crystal structure of a CCG‐repeat sequence, which shows that two dT(CCG) 3 A strands can associate to form a tetraplex structure with an i‐motif core containing four C:C + pairs flanked by two G:G homopurine base pairs as a structural motif. The tetraplex core is attached to a short parallel‐stranded duplex. Each hairpin itself contains a central CCG loop in which the nucleotides are flipped out and stabilized by stacking interactions. The helical twists between adjacent cytosine residues of this structure in the i‐motif core have an average value of 30°, which is greater than those previously reported for i‐motif structures.
Outage analysis of multi-node amplify-and-forward relay networks (2006)

In this paper, we consider the outage probability analysis of multi-node amplify-and-forward relay network with N relay nodes helping the source. We consider a system in which each relay node amplifies the source signal only. We obtain an approximation for the outage probability which is tight at high signal-to-noise ratio (SNR). This tight outage approximation shows that the system can achieve a maximum diversity of order N+1. For the case of N = 1, our approach gives the same result obtained previously by Laneman et al. for the single relay scenario.
SBFT: a Scalable Decentralized Trust Infrastructure for Blockchains. (2018)

We present SBFT: a scalable decentralized trust infrastructure for Blockchains. SBFT implements a new Byzantine fault tolerant algorithm that addresses the challenges of scalability and decentralization. Unlike many previous BFT systems that performed well only when centralized around less than 20 replicas, SBFT is optimized for decentralization and can easily handle more than 100 active replicas. SBFT provides a smart contract execution environment based on Ethereum's EVM byte-code. 
We tested SBFT by running 1 million EVM smart contract transactions taken from a 4-month real-world Ethereum workload. In a geo-replicated deployment that has about 100 replicas and can withstand $f=32$ Byzantine faults our system shows speedups both in throughput and in latency. SBFT completed this execution at a rate of 50 transactions per second. This is a $10\times$ speedup compared to Ethereum current limit of $5$ transactions per second. SBFT latency to commit a smart contract execution and make it final is sub-second, this is more than $10\times$ speedup compared to Ethereum current $>15$ second block generation for registering a smart contract execution and several orders of magnitude speedup relative to Proof-of-Work best-practice finality latency of one-hour.
An Efficiency Based Approach for the Energy Management in HEVs (2022)

A proper Energy Management Strategy (EMS) is a cornerstone for Hybrid Electric Vehicles consumption minimization. In general, to find the global optimal strategy, the knowledge of the entire mission profile of the vehicle is needed, making the real-time implementation impossible. A well-known solution to this problem is the Equivalent Consumption Minimization Strategy (ECMS) that optimizes at each time instant an equivalent fuel consumption, which combines the real fuel rate and a virtual fuel associated to the use of the battery energy. This virtual fuel is the actual battery power weighted by an equivalence factor, that implicitly accounts for the battery recharge efficiency during the vehicle mission. In this work, we propose an effciency based EMS, rather than a fuel consumption based one. Despite the two approaches are proven to be identical under some assumptions, in the efficiency based solution the defnition of the equivalence factor results easier. An offline estimation of this quantity is firstly proposed, eventually extended with a real-time adaptation. Simulation results show the effectiveness of the proposed approach, in particular when the adaptive strategy is used.