gebhart/patrepeval huggingface dataset:
Out of core testing of the North Carolina State University PULSTAR reactor positron beam (2007)

Out of core tests were performed on the North Carolina State University intense positron beam, prior to insertion into beamport number 6 of the PULSTAR nuclear reactor The beam optics were tested independently of the positron converter/moderator using beams of electrons and the performance of the extraction lenses was found to be in good agreement with the results of design simulations. The moderators were installed and tested by irradiating them with gamma-rays from a Na-24 source. Consequently, positrons (produced through pair production in the converter) were detected at the end of the beamline with a micro channel plate detector. By scaling the count rate obtained with the Na-24 source, to the energy dependent gamma flux in the beamport, the projected positron count rate is estimated at around 5.2 times 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">8</sup> e <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">+</sup> /s.
Step Change Jar Technology Redefines Industry Standards in North Sea Region (2012)

Abstract While jar technology has been used in the oil industry for the better part of the last century, the basic function and capability has not taken many leaps forward. Increasingly complex well geometry and deeper target depths continue to push drillers into tighter, higher risk well conditions that raise the probability of stuck pipe events. As demand for hydrocarbons has forced our drilling capabilities to evolve, the increased risk associated with these wells has forced the evolution of jarring technology to drastically evolve. By assessing the critical needs of the industry, a jar has been designed to operate in the harshest environments, with superior reliability, and the highest firing loads available to increase the levels of success in freeing a drill string during a stuck pipe event. Every pound of impact force delivered is critical to improve the chances of retrieving the drill string safely to surface and this new technology has raised the standard force by as much as 20%. While the operation of this innovative technology remains consistent with industry standards, the performance in regards to torsional strength, damage resistance, and impact capabilities far exceed that of previously existing jar technology. An optional performance component offers operators a safeguard against pulling the jar beyond its mechanical and hydraulic limits which can render it useless down hole. In addition to safeguarding the tool from damage, this module also allows the tool to be pulled to its maximum rating, every time, insuring the hardest possible impact every pull. This paper will detail how the use of this innovative tool has provided flawless performance in the North Sea and offers a true step change in jar technology to the drilling industry. Case studies and field data provided will support and demonstrate increased performance unmatched in the industry today.
Carrier Frequency Offset Compensation with Successive Cancellation in Uplink OFDMA Systems (2006)

Similar to OFDM systems, OFDMA systems also suffer from frequency mismatches between the receiver and the transmitter. However, the fact that each uplink user has a different frequency offset makes the compensation more challenging than that of OFDM systems. This paper proposes successive interference cancellation (SIC) for compensating the frequency offset in the uplink OFDMA systems. A decorrelator is used to remove the inter-carrier interference (ICI) within a user's signal and successive cancellation is applied to mitigate the multi access interference (MAI) arising due to the frequency difference among uplink users. The proposed algorithm is shown to eliminate the interference and has a manageable complexity.
Identification of Allyl Esters in Garlic Cheese (2007)

This study describes the identification of six allyl esters in a garlic cheese preparation and in a commercial cream cheese. The extracts were prepared by liquid/liquid extraction and concentrated by the SAFE process. The identification of the allyl esters of acetic, butyric, hexanoic, heptanoic, octanoic, and decanoic acids is based on the correlation of their mass spectrometric data and chromatographic retention time data obtained from the extracts with those of authentic standards. In addition to the gas chromatography (GC)/mass spectrometry analysis, the flavor ingredients were characterized by GC sniffing by a trained flavorist. Some of the esters were isolated by preparative GC.
First prototype of conversational H.C. Andersen (2004)

This paper describes the implemented first prototype of a domain-oriented, conversational edutainment system which allows users to interact via speech and 2D gesture input with life-like animated fairy-tale author Hans Christian Andersen.
Lateral Transfer of the Flexor Digitorum Longus for Peroneal Tendinopathy (2019)

Level IV, retrospective case series.
Synthesizing datapath circuits for FPGAs with emphasis on area minimization (2003)

Large circuits, whether they are arithmetic, digital signal processing, switching, or processors, typically contain a greater portion of highly regular datapath logic. Datapath synthesis algorithms preserve these regular structures, so they can be exploited by packing, placement, and routing tools for speed or density. Typical datapath synthesis algorithms, however, sacrifice area to gain regularity. Current algorithms can have as much as 30% to 40% area inflation when compared with traditional flat synthesis algorithms. This paper describes a datapath synthesis algorithm with very low area overhead, which is an enhancement to the module compaction algorithm. We propose two word-level optimizations - multiplexer tree collapsing and operation reordering. They reduce the area inflation to 3%-8% as compared with flat synthesis. Our synthesis results also retain significant amount of regularity from the original designs.
Fast End-to-End Wikification (2019)

Wikification of large corpora is beneficial for various NLP applications. Existing methods focus on quality performance rather than run-time, and are therefore non-feasible for large data. Here, we introduce RedW, a run-time oriented Wikification solution, based on Wikipedia redirects, that can Wikify massive corpora with competitive performance. We further propose an efficient method for estimating RedW confidence, opening the door for applying more demanding methods only on top of RedW lower-confidence results. Our experimental results support the validity of the proposed approach.
Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient‐derived xenograft (PDX) models (2018)

Our results demonstrate the clinical relevance of this series of PDXs as a platform for both basic science studies and therapeutic discovery/drug development. The present report provides the prostate cancer community with a summary of the basic characteristics and a contact information for collaborations using these models.
Silane-Grafted Isotactic Polypropylene Used as a Coupling Agent on Glass. Consequences on The Interfacial Adhesion (1996)

Abstract Functionalized isotactic polypropylenes have been synthetized in order to be used as coupling agents on glass fibers associated with a polypropylene matrix. This new way of interface toughening requires a grafting of such polymeric chains on the glass surface and a crystallization of these grafted chains at the same time in the same crystals as the polypropylene matrix (co-crystallization). Using a Ziegler-Natta polymerization, copolymers based on propene and two different types of dienes have been prepared. Such a synthesis allows one to change the functionality and the position of double bonds used to introduce the silane functions. A Speier hydrosilylation was used for this purpose with two kinds of silanes. Silane-functionalized oligopropenes were also prepared in order to compare the effect of the position of the silane functions on the glass/polypropylene adhesion: side chain or chain end positions. The characterization of these functionalized polypropylenes is described. Their ability to be grafted on a glass surface was checked by means of wetting measurements after extractions according to the hydrophobic nature of the polypropylene and the hydrophilic character of the glass. The co-crystallization of the pure and functionalized polypropylenes was demonstrated on blends. Two silane functionalized-PP were selected to study the glass fiber/PP adhesion by means of the microdroplet test.
What are you looking for? (2007)

Web search services are among the most heavily used applications on the World Wide Web. Perhaps because search is used in such a huge variety of tasks and contexts, the user interface must strike a careful balance to meet all user needs. We describe a study that used eye tracking methodologies to explore the effects of changes in the presentation of search results. We found that adding information to the contextual snippet significantly improved performance for informational tasks but degraded performance for navigational tasks. We discuss possible reasons for this difference and the design implications for better presentation of search results.
An Examination of the Efficacy of a Brief Educational Program on Driver Distraction (2003)

A study examined the influence of a brief educational intervention on self-reports of past and intended future distracted driving behavior, and on perception of the danger of various driver distractions (e.g. map reading, grooming, etc). Respondents completed a series of rating scales, reporting (A) the frequency with which they had participated in various distracting activities while driving in the past, (B) the frequency with which they expected to participate in those activities in the future, and (C) the perceived danger of those activities. Half of the respondents completed the rating scales after first watching a series short animated videos from the driver education program. The remaining respondents (controls) completed the surveys prior to viewing the video segments. As compared to the control subjects, participants who viewed the video segments prior to filling out the rating scales reported reliably higher levels of perceived danger for a number of distracting activities. Video segments did not, however, appear to affect respondents’ anticipated future behavior.
Wide-bandwidth InP/InGaAsP/InGaAs avalanche photodiodes grown by chemical beam epitaxy (1987)

Efforts to utilize existing fiber cables for the ever-expanding telecommunications marketplace has stimulated efforts to increase the circuit capacity of lightwave systems. One of the most obvious approaches has been to increase the rate of transmission and this appears to be leading to what may be referred to as the "multigigabit/s era". In order to achieve high receiver sensitivities at these high bit rates it is essential that avalanche photodiodes (APDs) with multigigahertz bandwidths be developed. To date, the SAGM-APD structure has demonstrated the highest operating frequencies. It consists of a wide-bandgap multiplication region and a narrow-bandgap absorbing layer separated by a transition region to improve the frequency response. In this paper we report InP/InGaAsP/InGaAs SAGM-APDs grown by chemical beam epitaxy that have exhibited bandwidths as high as 8 GHz and gain-bandwidth products of 70 GHz. We also discuss the factors that determine their frequency response.
Long-Term Integrity of Waste Package Final Closure for HLW Geological Disposal, (II) (2005)

Overpack, a high-level radioactive waste package for geological disposal, seals vitrified waste and in line with Japan's waste management program is required to isolate it from contact with groundwater for 1,000 years. In this study, TIG (Tungsten Inert Gas) welding method, a typical arc welding method and widely used in various industries, was examined for its applicability to seal a carbon steel overpack lid with a thickness of 190 mm. Welding conditions and welding parameters were examined for multi-layer welding in a narrow gap for four different groove depths. Weld joint tests were conducted and weld flaws, macro- and microstructure, and mechanical properties were assessed within tentatively applied criteria for weld joints. Measurement and numerical calculation for residual stress were also conducted and the tendency of residual stress distribution was discussed. These test results were compared with the basic requirements of the welding method for overpack which were pointed out in our first report. It is assessed that the TIG welding method has the potential to provide the necessary requirements to complete the final closure of overpack with a maximum thickness of 190 mm.
Clinical Implications of Ultrasonic Tissue Characterization for Atherosclerotic Carotid Intima-Media. (2000)

Current imaging modalities, such as ultrasonic tissue characterization, have enabled accurate determination of the composition of atherosclerotic plaque of excised aortic tissue. The aim of this study is to compare integrated backscatter (IBS) echo signals of the intima-media complex of human carotid arteries between young and elderly subjects, and to evaluate the ability of ultrasonic tissue characterization. We compared the difference in ultrasonic parameters between the carotid arteries of young healthy subjects (n = 27, 25 +/- 1 y.o.) and elderly subjects (n = 55, 75 +/- 4 y.o.). Intima-media thickness (IMT) and calibrated IBS value (C-IBS: Tissue IBS-vessel lumen IBS value) were measured. The IMT values of young and elderly subjects were 0.54 +/- 0.03 and 1.08 +/- 0.07 mm, respectively (p < 0.01). C-IBS of elderly subjects (11.7 +/- 0.8 dB) was significantly higher than that of young subjects (6.9 +/- 0.7 dB). Significantly wider standard deviation of C-IBS value in each individual was observed in elderly subjects (mean +/- SE of individual standard deviation in C-IBS: 4.2 +/- 0.9 dB) compared with that in young subjects (1.7 +/- 0.3 dB). This might reflect varied composition of atherosclerotic plaques in elderly subjects. IBS analysis would become a promising method to distinguish plaque composition quantitatively and to assess the stability of plaques in clinical setting.
C4ISR Forward...A Vision for the Future (1997)

Abstract : A key element in the 1997 NRaD Strategic Plan is the strategy to develop and articulate an integrated vision for C4ISR. The responsibility for this was assigned to the Corporate Initiatives Group (CIG), an NRAD Interdepartmental team charged with articulation of long-range, coordinated activities that promote our primary corporate missions. The publication of this document and subsequent briefings and brochures fulfill this assignment. The vision contained in this document has my full support and that of your Executive Board. It crosses all of our Department boundaries and focuses on interdepartmental thinking and teaming. Its scope is NRaD wide.
THE TARGET SIGN (2022)

Our results show distinct imaging findings present in all patients with fundus albipunctatus independent of ethnicity or genetic mutation. Our results can facilitate the current algorithm to diagnose RDH5-related fundus albipunctatus and allow for targeted genetic testing.
USING ACCELEROMETRY TO TRACK CLINICAL TRAJECTORIES: AORTIC VALVE REPLACEMENT AS AN EXAMPLE (2017)

Accelerometry technology has been used to capture motion in studies of physical activity, where these instruments have been used to assess the total amount of activity and its intensity. Clinicians have begun to realize that these characteristics could provide information about underlying health status and the use of monitors to predict clinical outcomes has increased. This presentation will review current applications of accelerometers in clinical practice. Using data from a pilot study of 53 patients undergoing aortic valve replacement either through open heart surgery or through transcatheter valve replacement, we will show the pre-intervention accelerometry data. We will then compare post-intervention accelerometry data over time, illustrating where there are significant differences between the types of valve replacement and between the pre- and the post-intervention accelerometry data. Accelerometry technology has been used to capture motion in studies of physical activity, where these instruments have been used to assess the total amount of activity and its intensity. Among other characteristics analyzed from the raw accelerometry signal include time spent sedentary, time in sleep, duration of bouts of motion, and time walking. Clinicians have begun to realize that these characteristics could provide information about underlying health status and the use of monitors to predict clinical outcomes has increased. This presentation will review current applications of accelerometers in clinical practice. Using data from a pilot study of 53 patients undergoing aortic valve replacement either through open heart surgery or through transcatheter valve replacement, we will show the pre-intervention accelerometry data. We will then compare post-intervention accelerometry data over time, illustrating where there are significant differences between the types of valve replacement and between the pre- and the post-intervention accelerometry data.
Christiane F. : Wir kinder vom Bahnhof Zoo (2009)

FSK ab 16 freigegeben
A privacy framework for mobile health and home-care systems (2009)

In this paper, we consider the challenge of preserving patient privacy in the context of mobile healthcare and home-care systems, that is, the use of mobile computing and communications technologies in the delivery of healthcare or the provision of at-home medical care and assisted living. This paper makes three primary contributions. First, we compare existing privacy frameworks, identifying key differences and shortcomings. Second, we identify a privacy framework for mobile healthcare and home-care systems. Third, we extract a set of privacy properties intended for use by those who design systems and applications for mobile healthcare and home-care systems, linking them back to the privacy principles. Finally, we list several important research questions that the community should address. We hope that the privacy framework in this paper can help to guide the researchers and developers in this community, and that the privacy properties provide a concrete foundation for privacy-sensitive systems and applications for mobile healthcare and home-care systems.
Docetaxel-based induction therapy prior to radiotherapy with or without docetaxel for non-small-cell lung cancer (2006)

This trial aimed to assess the feasibility and tumour control of concurrent chemoradiotherapy or radiotherapy alone after docetaxel-based induction chemotherapy in locally advanced non-small-cell lung cancer (NSCLC). Patients with stage IIIA/IIIB NSCLC received two 21-day cycles of induction chemotherapy with docetaxel (85 mg m(-2), day 1) plus cisplatin (40 mg m(-2), days 1 and 2). Patients without disease progression on day 43 were randomised to radiotherapy (2 Gy for 5 days week(-1); total 60 Gy) alone or with docetaxel 20 mg m(-2) once weekly every 6 weeks. Of 108 patients who received induction chemotherapy, 104 were evaluable for response. After induction chemotherapy, the overall response rate (ORR) was 44%; 91 (88%) patients had no disease progression and 89 were subsequently randomised to local treatment. After randomised therapy, the ORR was 53% (chemoradiotherapy 58%; radiotherapy 48%). Median survival and time to progression were 14.9 and 7.8 months, respectively, for chemoradiotherapy and 14.0 and 7.5 months, respectively, for radiotherapy. The most common toxicities during induction chemotherapy and randomised therapy were grades 3-4 neutropenia and grade 3 lymphocytopenia, respectively. Docetaxel-cisplatin induction therapy followed by concurrent docetaxel and thoracic radiotherapy is a feasible treatment option, showing good clinical activity and tolerability, for locally advanced NSCLC.
Anaesthesia for intracranial vascular surgery and carotid disease (2011)

The intracranial pressure (ICP) has three components: an arterial vascular component; a cerebrospinal fluid (CSF) circulatory component; and a venous outflow component. More generally, multiple variables such as the arterial pulsatile pressure, autoregulation and cerebral venous outflow all contribute to the vascular component. Intracranial compliance is a concept often associated with CSF storage. Measurement of brain compliance is classically performed using a CSF bolus injection. In sedated patients with TBI, continuous ICP monitoring is recommended, and can only be achieved by direct invasive measurement. The gold standard for ICP monitoring is a catheter inserted into the lateral ventricle and connected to an external pressure transducer. Cerebral perfusion pressure (CPP)-oriented therapy has been introduced to decrease the risk of ischaemia in post-injury care. Intracranial pressure waveforms include distinct periodic components: heart pulse waves, respiratory waves and quasi-periodic slow vasogenic waves.
Evaluating the robustness of targeted maximum likelihood estimators via realistic simulations in nutrition intervention trials (2022)

Several recently developed methods have the potential to harness machine learning in the pursuit of target quantities inspired by causal inference, including inverse weighting, doubly robust estimating equations and substitution estimators like targeted maximum likelihood estimation. There are even more recent augmentations of these procedures that can increase robustness, by adding a layer of cross-validation (cross-validated targeted maximum likelihood estimation and double machine learning, as applied to substitution and estimating equation approaches, respectively). While these methods have been evaluated individually on simulated and experimental data sets, a comprehensive analysis of their performance across real data based simulations have yet to be conducted. In this work, we benchmark multiple widely used methods for estimation of the average treatment effect using ten different nutrition intervention studies data. A nonparametric regression method, undersmoothed highly adaptive lasso, is used to generate the simulated distribution which preserves important features from the observed data and reproduces a set of true target parameters. For each simulated data, we apply the methods above to estimate the average treatment effects as well as their standard errors and resulting confidence intervals. Based on the analytic results, a general recommendation is put forth for use of the cross-validated variants of both substitution and estimating equation estimators. We conclude that the additional layer of cross-validation helps in avoiding unintentional over-fitting of nuisance parameter functionals and leads to more robust inferences.
Mismatch repair deficiency, next-generation sequencing-based microsatellite instability, and tumor mutational burden as predictive biomarkers for immune checkpoint inhibitor effectiveness in frontline treatment of advanced stage endometrial cancer (2023)

Immune checkpoint inhibitors may have improved efficacy over chemotherapy in frontline treatment for advanced endometrial cancer defined by MSI-high using next-generation sequencing as a nominally better predictor of outcomes than dMMR with immunohistochemistry. This provides the biologic rationale of active phase III trials.