gebhart/patrepeval huggingface dataset:
Proceedings of the 10th ACM SIGPLAN/SIGOPS international conference on Virtual execution environments (2014)

Welcome to the 10th ACM SIGPLAN/SIGOPS Conference on Virtual Execution Environments (VEE'14). We are happy to present the community with a strong program covering a wide range of virtualization topics.

This year, authors registered 56 papers, of which 49 were finalized as complete submissions. The program committee (PC) consisted of 2 chairs and 18 researchers active in virtualizationrelated aspects of programming languages and operating systems. Members were allowed to submit papers; the co-chairs chose not to submit anything. Reviewing was double-blind and was done almost entirely by the committee, with a little assistance from outsiders with special expertise. All submissions received 4-5 reviews, and authors were given the opportunity for rebuttal before the PC meeting.

The program committee meeting was held in January at the IBM T.J. Watson Research Center in New York. Most of the committee members were present in person. In an 8-hour session, we individually discussed all papers but those that were marked as early rejects due to receiving only negative reviews. We followed conventional rules for conflict of interest, with conflicted members (including co-chairs) leaving the room during discussion of the conflicted papers. In the end, we accepted 18 papers for presentation at the conference, of which about half were shepherded by PC members.

In addition to the 18 accepted papers, the VEE'14 program includes two keynote presentations by Galen Hunt and Jan Vitek. We hope that the resulting proceedings will serve as a valuable reference for researchers and practitioners in the area of virtualization.
Rhesus monkeys protected against Plasmodium knowlesi malaria produce antibodies against a 65,000-MrP. knowlesi glycoprotein at the surface of infected erythrocytes (1981)

Sera from 27 rhesus monkeys immunized in various ways against the H strain of Plasmodium knowlesi were analyzed by quantitative crossed immunoelectrophoresis. The reaction of the sera was compared with a reference immune serum only reactive with P. knowlesi-specific 65,000-Mr glycoprotein-immune component 13 (gp65/ic13) in membranes of infected rhesus monkey erythrocytes. Triton X-100-solubilized, 125I-labeled membranes of schizont-infected erythrocytes were used as an antigen. Sera from 9 or 10 monkeys immunized by repeated infections with P. knowlesi reacted with gp65/ic13. In 6 of 10 sera, anti-gp65/ic13 was the only antibody reacting with host cell membrane proteins. In contrast, vaccination of 15 monkeys with predominantly sexual stages or trophozoites of P. knowlesi in Freund complete adjuvant resulted in protection against blood challenges in 7 monkeys, only 2 of which contained precipitating antibody against gp65/ic13. None of the sera from monkeys not protected by infections or vaccinations contained detectable levels of precipitating antibodies against gp65/ic13. Our data indicate that gp65/ic13 acts as a prominent immunogen in vivo during natural p. knowlesi infections of rhesus monkeys. There is a positive correlation suggested between anti-gp65/ic13 antibody and protection in the monkeys analyzed. This correlation does not apply to monkeys protected against P. knowlesi malaria by vaccination, pointing to other effective immune defense mechanisms.
Possible role of individual protein-DNA contacts of Flp site-specific recombinase from Saccharomyces cerevisiae with nucleic bases of Flp-binding element of DNA (1996)

Сайт-специфическая рекомбиназа Flp, кодируемая 2-мкм плазмидой из S. cerevisiae, имеет множественные точечные контакты с основаниями Flp-связывающего элемента ДНК. В настоящей работе проведен анализ относительного вклада контактов в прочность связывания белка Flp с ДНК и особенностей их распределения в большом и малом желобке ДНК. Контакты белка Flp с Flp-связывающим элементом ДНК были подразделены на три группы в зависимости от их вклада в прочность связывания белка с ДНК. Предполагается, что белок Flp использует контакты третьей группы, которая вносит наименьший вклад в прочность связывания, наряду с контактами в малом желобке ДНК для первичной дискриминации между различными последовательностями ДНК Показано, что белок Flp имеет контакты с Flp-связывающим элементом ДНК в малом желобке с противоположных сторон двойной спирали ДНК, и, вероятно, белок Flp оплетает ДНК.
Quantifying Spectral Sensitivity Mismatch Using a Metameric Color Rule (2018)

A new camera metric is proposed based, in concept, on the vision test devised by Davidson and Hemmendinger. The "D&amp;H Color Rule" is a set of two linear patch arrays containing at most one match for near-normal color observers. The match selected by an observer can provide an indication of how that observer's color vision relates to others. Comparisons may be made to a group of interest, or more commonly, to a CIE Standard Observer. For this research, two image targets have been created, one physical and one virtual, each with a family of spectra related in much the same way as the colors in the original D&amp;H Rule. These targets can be physically imaged or virtually modeled to predict camera RGB, and then CIELAB with a color profile. The camera can then be judged as to what degree its output matches that of a CIE Standard Observer. &#xA9; 2018 Society for Imaging Science and Technology.
Synthesis and characterization of poly(arylene ether imidazole)s (1991)

Abstract Poly(arylene ether imidazole)s were prepared by the aromatic nucleophilic displacement reaction of a bisphenol imidazole with activated aromatic dihalides. The polymers had glass transition temperatures ranging from 230 to 318°C and number‐average molecular weights as high as 82,000 g/mol. Thermogravimetric analysis showed a 5% weight loss occurring ∼ 400°C in air and ∼ 500°C in nitrogen. Typical neat resin mechanical properties obtained at room temperature included tensile strength and tensile modulus of 14.2 and 407 ksi and fracture energy ( G lc ) of 23 in. lb/in. 2 Titanium‐to‐titanium tensile shear strengths measured at 23 and 200°C were 4800 and 3000 psi, respectively. In addition, preliminary data were obtained on carbon fiber laminates. The chemistry, physical, and mechanical properties of these polymers are discussed.
Disorder classification of the vibrational spectra of modern glasses (2021)

Using the coherent-potential approximation in heterogeneous-elasticity theory with a log-normal distribution of elastic constants for the description of the Raman spectrum and the temperature dependence of the specific heat, we are able to reconstruct the vibrational density of states and characteristic descriptors of the elastic heterogeneity of a wide range of glassy materials. These descriptors are the nonaffine contribution to the shear modulus, the mean-square fluctuation of the local elasticity, and its correlation length. They enable a physical classification scheme for disorder in modern, industrially relevant glass materials. We apply our procedure to a broad range of real-world glass compositions, including metallic, oxide, chalcogenide, hybrid, and polymer glasses. Universal relationships between the descriptors on the one side, and the height and frequency position of the boson peak, the Poisson ratio and the liquid fragility index on the other side are established.
DNA Sequences in Cationic Lipid:pDNA-Mediated Systemic Toxicities (2003)

Systemic delivery of synthetic gene transfer vectors such as cationic lipid:plasmid DNA (pDNA) complexes elicits a range of acute physiologic responses, which in the context of therapeutic gene delivery represent dose-limiting toxicities. The most prominent responses are transient leukopenia, thrombocytopenia, serum transaminase elevations, and elevations of proinflammatory cytokines such as interferon-gamma (IFN-gamma), interleukin-12 (IL-12), and tumor necrosis factor-alpha (TNF-alpha). The unmethylated CpG sequences present in plasmid DNA have been implicated as a major cause of the robust cytokine response that follows systemic administration of cationic lipid:pDNA complexes. However, the factors causing the additional significant toxicities (leukopenia, thrombocytopenia, and serum transaminase elevations) recently shown to be associated with vector administration have not been defined. We show here that DNA sequences, such as immune stimulatory CpG sequences, play a significant role in inducing the additional acute toxicities associated with cationic lipid:pDNA complex administration. Importantly, while methylating these CpG sequences results in greatly reduced cytokine levels, this modification does not eliminate their ability to generate the other systemic toxicities. Examples of non-CpG DNA sequences that induce distinct toxicity profiles when administered systemically in the form of cationic lipid:DNA complexes are also identified. Taken together, these results imply that specific DNA sequences are responsible for a significant portion of the systemic toxicities observed after administration of cationic lipid:pDNA complexes.
A Perspective: Regulation of IgE Receptor-Mediated Mast Cell Responses by a LAT-Organized Plasma Membrane-Localized Signaling Complex (2001)

The results demonstrate that LAT is a central mediator in IgE receptor signaling by regulating multiple signaling pathways that affect mast cell degranulation and cytokine production. Vav1, a component of this LAT-containing signaling complex, regulates a specific subset of these responses.
Initial growth analysis of ALD Al 2 O 3 film on hydrogen-terminated Si substrate via in situ XPS (2019)

Abstract The initial stage of Al 2 O 3 films deposited by atomic layer deposition (ALD) on a H-terminated Si(001) wafer was investigated with in situ X-ray photoelectron spectroscopy. At deposition temperatures of 250 °C and 300 °C, no Al peak was detected for the first 10 ALD cycles. An Al peak was first observed at ALD cycle 12, and its intensity increased with increasing ALD cycle number. The 10 initial ALD cycles were defined as an incubation period. The Si 2p and Al 2p narrow spectra indicated that Si sub-oxide formed during the incubation period and trimethylaluminum (TMA) adsorbed on it after the incubation period. The incubation period at a growth temperature of 350 °C decreased to five ALD cycles because the H 2 O exposure at a higher temperature promoted the oxidation of the H-terminated Si surface and formed Si sub-oxide.
Front Cover: Lignin Valorization by Cobalt‐Catalyzed Fractionation of Lignocellulose to Yield Monophenolic Compounds (ChemSusChem 2/2019) (2019)

The Front Cover shows a “Lignin-First approach” where birch wood is fractionated and simultaneously the lignin is reductively depolymerized. For the first time, a heterogeneous cobalt catalyst is used instead of noble metal-based catalysts. The cobalt was immobilized on a nitrogen doped carbon support to form Co-phen/C. Noteworthy, the catalytic system can generate monophenolic compounds in 76% of the theoretical maximum yield from lignin. Mechanistic studies show that the role of the catalyst is both to stabilize reactive monomers that are released from the wood by solvolysis and to cleave the β-O-4' bond in oligomeric/polymeric fragments. More information can be found in the Communication by Rautiainen et al. on page 404 in Issue 2, 2019 (DOI: 10.1002/cssc.201802497).
Nanoplasmonic Sensing for Monitoring the Initial Stages of Atmospheric Corrosion of Cu Nanodisks and Thin Films (2013)

Nanoplasmonic sensing as a powerful experimental technique for corrosion kinetics monitoring is demonstrated. Its versatility is illustrated by studies of initial corrosion carried out on model systems consisting of copper nanodisks and extended copper films in both dry (
Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells (2017)

Triggering of the complement cascade induces tumor cell lysis via complement-dependent cytotoxicity (CDC) and attracts and activates cytotoxic cells. It therefore represents an attractive mechanism for mAb in cancer immunotherapy development. The classical complement pathway is initiated by IgG molecules that have assembled into ordered hexamers after binding their Ag on the tumor cell surface. The requirements for CDC are further impacted by factors such as Ab epitope, valency, and affinity. Thus, mAb against well-validated solid tumor targets, such as the epidermal growth factor receptor (EGFR) that effectively induces complement activation and CDC, are highly sought after. The potency of complement activation by IgG Abs can be increased via several strategies. We identified single-point mutations in the Fc domain (e.g., E345K or E430G) enhancing Fc:Fc interactions, hexamer formation, and CDC after Ab binds cell-surface Ag. We show that EGFR Abs directed against clinically relevant epitopes can be converted into mAb with unprecedented CDC activity. Alternative strategies rely on increasing the affinity of monomeric IgG for C1q by introduction of a quadruple mutation at the C1q binding site or via generation of an IgG1/IgG3 chimera. In this study we show that selective enhancement of C1q binding via avidity modulation is superior to the unattended increase in C1q binding via affinity approaches, particularly for target cells with reduced EGFR expression levels. Improving Fc:Fc interactions of Ag-bound IgG therefore represents a highly promising and novel approach for potentiating the anti-tumor activity of therapeutic mAb against EGFR and potentially other tumor targets.
A critical RCU safety property is... ease of use! (2019)

Some might argue that read-copy update (RCU) is too low-level to be targeted by hackers, but the advent of Row Hammer [19] demonstrated the naïveté of such views. After all, if black-hat hackers are ready, willing, and able to exploit hardware bugs such as Row Hammer, they are assuredly ready, willing, and able to exploit bugs in RCU. Nor is it any longer the case that RCU's involvement in exploitable Linux-kernel bugs is strictly theoretical. However, this bug involved not RCU's correctness, but rather its ease of use. Nevertheless, it was a real bug that really needed fixing. This paper describes this bug and the road to its eventual fix.
Safety and Immunogenicity of a 13-valent Pneumococcal Conjugate Vaccine in Healthy Infants and Toddlers Given With Routine Pediatric Vaccinations in Canada (2011)

Responses to routine childhood vaccines did not differ with PCV7 or PCV13 coadministration. Serotype-specific pneumococcal antibody concentrations were protective. The safety profile of PCV13 was favorable.
OverLay (2015)

The idea of augmented reality - the ability to look at a physical object through a camera and view annotations about the object - is certainly not new. Yet, this apparently feasible vision has not yet materialized into a precise, fast, and comprehensively usable system. This paper asks: What does it take to enable augmented reality (AR) on smartphones today? To build a ready-to-use mobile AR system, we adopt a top-down approach cutting across smartphone sensing, computer vision, cloud offloading, and linear optimization. Our core contribution is in a novel location-free geometric representation of the environment - from smartphone sensors - and using this geometry to prune down the visual search space. Metrics of success include both accuracy and latency of object identification, coupled with the ease of use and scalability in uncontrolled environments. Our converged system, OverLay, is currently deployed in the engineering building and open for use to regular public; ongoing work is focussed on campus-wide deployment to serve as a "historical tour guide" of UIUC. Performance results and user responses thus far have been promising, to say the least.
Long-Range Correlations between Aliphatic [superscript 13]C Nucleic in Protein MAS NMR Spectroscopy (2009)

Highly efficient polarization transfer can be achieved in the magic-angle spinning NMR analysis of proteins by the combination of [superscript 13]C labeling at alternating positions and band-selective radio-frequency-driven recoupling (BASE RFDR), a pulse scheme aimed at exploiting the bandwidth selectivity and favorable effects of weak [superscript 13]C radio-frequency irradiation to reintroduce the homonuclear dipolar interactions between distant nuclei.
Optimized intermolecular potential functions for amides and peptides. Hydration of amides (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOptimized intermolecular potential functions for amides and peptides. Hydration of amidesWilliam L. Jorgensen and Carol J. SwensonCite this: J. Am. Chem. Soc. 1985, 107, 6, 1489–1496Publication Date (Print):March 1, 1985Publication History Published online1 May 2002Published inissue 1 March 1985https://pubs.acs.org/doi/10.1021/ja00292a007https://doi.org/10.1021/ja00292a007research-articleACS PublicationsRequest reuse permissionsArticle Views737Altmetric-Citations200LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
An Image is Worth More than a Thousand Favorites: Surfacing the Hidden\n Beauty of Flickr Pictures (2015)

The dynamics of attention in social media tend to obey power laws. Attention\nconcentrates on a relatively small number of popular items and neglecting the\nvast majority of content produced by the crowd. Although popularity can be an\nindication of the perceived value of an item within its community, previous\nresearch has hinted to the fact that popularity is distinct from intrinsic\nquality. As a result, content with low visibility but high quality lurks in the\ntail of the popularity distribution. This phenomenon can be particularly\nevident in the case of photo-sharing communities, where valuable photographers\nwho are not highly engaged in online social interactions contribute with\nhigh-quality pictures that remain unseen. We propose to use a computer vision\nmethod to surface beautiful pictures from the immense pool of\nnear-zero-popularity items, and we test it on a large dataset of\ncreative-commons photos on Flickr. By gathering a large crowdsourced ground\ntruth of aesthetics scores for Flickr images, we show that our method retrieves\nphotos whose median perceived beauty score is equal to the most popular ones,\nand whose average is lower by only 1.5%.\n
Optical Dynamic Gain Equalizer using Parallel Motion Type of ECLIA (2003)

本研究では圧電および静電アクチュエータを組み合わせたECLIAについて研究を進めている。本発表では, ECLIAの光通信分野への応用例として, 並列動作型ECLIAを用いた可変利得等化器の研究成果を発表する。
Homologous Alkalophilic and Acidophilic l -Arabinose Isomerases Reveal Region-Specific Contributions to the pH Dependence of Activity and Stability (2012)

To study the pH dependence of l-arabinose isomerase (AI) activity and stability, we compared homologous AIs with their chimeras. This study demonstrated that an ionizable amino acid near the catalytic site determines the optimal pH (pH(opt)) for activity, whereas the N-terminal surface R residues play an important role in determining the pH(opt) for stability.
Periodic Sub-wavelength Electron Beam Lithography Defined Photonic Crystals for Mode Control in Semiconductor Lasers (2007)

Extract Extended abstract of a paper presented at Microscopy and Microanalysis 2007 in Ft. Lauderdale, Florida, USA, August 5 – August 9, 2007
Colon and Breast Anti-cancer Effects of Peptide Hydrolysates Derived from Rice Bran (2009)

Rice bran is an economical, under-utilized co-product of rough rice milling. The objective of this study was to produce rice-bran peptides and investigate for anti-cancer activity. Protein hydrolysates were prepared by treating heat stabilized defatted rice-bran with food grade Alcalase enzyme, followed by treatment with simulated gastric and intestinal juices to obtain resistant peptides. Resistant peptides were fractionated into &gt;50, 10-50, 5-10, and &lt;5 kDa sizes, freeze dried, and evaluated for inhibitory and cytotoxicity activities on human colon (HCT-116) and breast (HTB-26) cancer cell lines. The results showed that &lt;5 kDa fraction of rice-bran is a potent anti-cancer agent. The cytotoxicity of the fraction to both cancer cell types was more pronounced after the treatment with 500 µg/mL. The IC 50 of the peptide fraction was approximately 750 µg/mL. These results indicate that the &lt;5 kDa peptide fraction separated from rice bran protein hydrolysate has a potent anti-tumor activity for colon cancer cells. The peptide fractions that demonstrate anti-cancer activities have the potential for use as functional food ingredients for health benefits.
Localization of the Wilson disease protein in murine intestine (2008)

Wilson disease is an inherited disorder of human copper metabolism, characterized by gradual accumulation of copper in tissues, predominantly liver and brain. The gene defect lies in the Wilson disease protein ATP7B, a copper transporting ATPase highly active in hepatocytes. In the liver, ATP7B is essential for excretion of excess copper into the bile and for copper loading of ceruloplasmin in the Golgi apparatus. The extrahepatic role of ATP7B is not yet completely understood. We analysed the intestinal expression of ATP7B in mice using RT-PCR, Western blot and indirect immunofluorescence. We found abundant expression of ATP7B in stomach and small intestine, but not in colon. Using confocal microscopy we demonstrate a Golgi localization of ATP7B in enterocytes. In response to elevated copper, the Wilson disease protein shows an intracellular trafficking pattern in the intestinal polarized cell line CaCo-2, moving away from the Golgi apparatus to dispersed vesicles. This suggests a role for intestinal ATP7B in sequestration of copper in intracellular vesicles for maintenance of copper homeostasis in the enterocyte. In conclusion, the expression of ATP7B in the small intestine might represent an additional regulatory mechanism to fine-tune intestinal copper absorption.
Inferring the Causal Impact of New Track Releases on Music Recommendation Platforms through Counterfactual Predictions (2020)

With over 20,000 tracks being released each day, recommendation systems that power music streaming services should not only be responsive to such large volumes of content, but also be adept at understanding the impact of such new releases on, both, users’ listening behavior and popularity of artists. Inferring the causal impact of new track releases is critical to fully characterizing the interplay between artists and listeners, as well as among the artists. In this study, we infer and quantify causality using a diffusion-regression state-space model that constructs counterfactual outcomes using a set of synthetic controls, which predict potential outcomes in absence of the intervention. Based on large scale experiments spanning over 21 million users and 1 billion streams on a real world streaming platform, our findings suggest that releasing a new track has a positive impact on the popularity of other tracks by the same artist. Interestingly, other related and competing artists also benefit from a new track release, which hints at the presence of a positive platform-effect wherein some artists gain significantly from activities of other artists.