PD53-08 NON-INFECTIOUS COMPLICATIONS AFTER PROSTATE NEEDLE BIOPSY – OUTCOMES FOLLOWING OVER 8,000 BIOPSIES FROM THE PENNSYLVANIA UROLOGIC REGIONAL COLLABORATION (PURC) (2019)

You have accessJournal of UrologyGeneral & Epidemiological Trends & Socioeconomics: Quality Improvement & Patient Safety III (PD53)1 Apr 2019PD53-08 NON-INFECTIOUS COMPLICATIONS AFTER PROSTATE NEEDLE BIOPSY – OUTCOMES FOLLOWING OVER 8,000 BIOPSIES FROM THE PENNSYLVANIA UROLOGIC REGIONAL COLLABORATION (PURC) Adrian Sosenko*, Thomas Lanchoney, Thomas Guzzo, Edouard Trabulsi, John Danella, Mark Mann, Adam Reese, Jeffrey Tomaszewski, Serge Ginzburg, Robert Uzzo, Marc Smaldone, Claudette Fonshell, Bret Marlowe, and Jay Raman Adrian Sosenko*Adrian Sosenko* More articles by this author , Thomas LanchoneyThomas Lanchoney More articles by this author , Thomas GuzzoThomas Guzzo More articles by this author , Edouard TrabulsiEdouard Trabulsi More articles by this author , John DanellaJohn Danella More articles by this author , Mark MannMark Mann More articles by this author , Adam ReeseAdam Reese More articles by this author , Jeffrey TomaszewskiJeffrey Tomaszewski More articles by this author , Serge GinzburgSerge Ginzburg More articles by this author , Robert UzzoRobert Uzzo More articles by this author , Marc SmaldoneMarc Smaldone More articles by this author , Claudette FonshellClaudette Fonshell More articles by this author , Bret MarloweBret Marlowe More articles by this author , and Jay RamanJay Raman More articles by this author View All Author Informationhttps://doi.org/10.1097/01.JU.0000556976.70181.50AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVES: Prostate needle biopsy (PNB) remains the referent standard for the diagnosis of prostate cancer. Contemporary data highlights an increase in PNB related infections particularly when performed via the transrectal approach. Non-infectious complications, however, may similarly contribute to biopsy related morbidity. Appropriate patient counseling merits recognition and discussion of such risks. Therefore, we review the incidence and predictors of non-infectious complications following PNB in a large quality registry. METHODS: The Pennsylvania Urologic Regional Collaboration (PURC) is a physician-led quality collaborative focusing on prostate cancer diagnosis and therapy. Established in 2015, 9 participating practices encompassing 108 urologists have accrued over 8,100 men into this data registry. The incidence and distribution of non-infectious PNB complications were evaluated. Logistic regression determined the association of clinical and pathologic variables with the most common non-infectious complications. RESULTS: 8,102 men underwent a transrectal ultrasound guided biopsy of which 84% were an initial biopsy, 11% had one prior biopsy, and 5% had multiple prior biopsies. 277 of 8,102 (3.4%) men experienced a biopsy related complication including 199 (2.5%) that were non-infectious and 78 (0.9%) that were infection-related (p<0.001). The most common non-infectious complications included bleeding (n=74; 0.9%) and urinary retention (n=70; 0.9%). Of the 199 non-infectious complications, 111 (56%) resulted in an ED visit and 54 (27%) were admitted to the hospital. With respect to post-biopsy urinary retention, increasing gland size (OR 1.07 per 5cc increase, 95% CI 1.01−1.11, p=0.002) was associated with urinary retention whilst repeat biopsy (p=0.54), presence of cancer (p=0.35), and number of cores (p=0.72) obtained were not. For bleeding complications, no variables were identified to be associated with these events including prior biopsy (p=0.83), number of biopsy cores (p=0.19), presence of cancer (p=0.90), or chronic anticoagulation (p=0.26). CONCLUSIONS: Non-infectious complications following biopsy occurred in 2.5% of men with bleeding (0.9%) and urinary retention (0.9%) being the most common causes. Over 50% of these non-infectious complications required an ED visit and over one-quarter needed hospital admission. Such information provides an important framework in counseling patients regarding expectations following prostate biopsy. Source of Funding: none Hershey, PA; Hershey, PA; Hershey, PA; Hershey, PA; Philadelphia, PA; Hershey, PA; Philadelphia, PA; Hershey, PA; Herhsey, PA; Hershey, PA; Hershey, PA© 2019 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 201Issue Supplement 4April 2019Page: e933-e933 Advertisement Copyright & Permissions© 2019 by American Urological Association Education and Research, Inc.MetricsAuthor Information Adrian Sosenko* More articles by this author Thomas Lanchoney More articles by this author Thomas Guzzo More articles by this author Edouard Trabulsi More articles by this author John Danella More articles by this author Mark Mann More articles by this author Adam Reese More articles by this author Jeffrey Tomaszewski More articles by this author Serge Ginzburg More articles by this author Robert Uzzo More articles by this author Marc Smaldone More articles by this author Claudette Fonshell More articles by this author Bret Marlowe More articles by this author Jay Raman More articles by this author Expand All Advertisement PDF downloadLoading ...