gebhart/patrepeval huggingface dataset:
Solution and solid state NMR studies of some selenium analogues of auranofin (an anti-arthritic gold drug) (2005)

Three mixed ligand complexes of gold(I) with phosphines and selenones, [Et3PAuSe=C<]Br as analogues of auranofin (Et3PAuSR) have been prepared and characterized by elemental analysis, IR and NMR methods. A decrease in the IR frequency of the C=Se mode of selenones upon complexation is indicative of selenone binding to gold(I) via a selenone group. An upfield shift in 13C NMR for the C=Se resonance of the selenones and downfield shifts in 31P NMR for the R3P moiety are consistent with the selenium coordination to gold(I). 13C solid state NMR shows the chemical shift difference between free and bound selenone to gold(I) for ImSe and DiazSe to be ca 10 and 17 ppm respectively. Large 77Se NMR chemical shifts (55 ppm) upon complexation in the solid state for [Et3PAuDiazSe]Br compared to [Et3PAuImSe]Br (10 ppm) indicates the former to be more stable and the Au–Se bond to be stronger than in the latter complex.
Target localization in natural or jumbled environment: relative influence of scene and object spatial signatures (2010)

Scenes of the outside world share a common characteristic: they have specific statistical properties distinguishing them from purely random images. In the frame of natural images, scenes exhibit a spatial structure and dominant orientation regularities evocative of their category membership (Guérin-Dugué, Bernard and Oliva, 1998, Perception, 27, 151 ; Oliva and Torralba, 2001, International Journal of Computer Vision, 42,145–175). These global properties lead to defining the concept of scene spatial signature. The aim of the current study was to measure the influence of this specific global information of the scene on the localization of local targets. Three experiments investigated the relative weight of both global and local levels of information. A jumbling paradigm, borrowed from Biederman's study (1972, Science, 177, 77–80), allowed to control the local spatial organization around the target as well as the relative spatial arrangement of elements in the whole scene. Test images were filtered or unfiltered. Low-pass filtering of the images impaired the physical description of the target. Results showed that, initially, when images were blurred, the global structure played a major role. However, after a learning period, subjects started using the invariant distinctive features of the target to localize it whatever the aspect of the scene. In analogy to the scene spatial signature, these local information distinguishing the target from its close environment may define the object spatial signature. This perceptual learning process frees the subjects from having to rely on global information. The present study shows that perceptual strategies are not determined once and for all. The visual system is flexible and juggles with the various information available at both global and local levels to adapt to visual constraints.
Habitat risk assessment for regional ocean planning in the U.S. Northeast and Mid-Atlantic (2018)

Coastal habitats provide important benefits to people, including habitat for species targeted by fisheries and opportunities for tourism and recreation. Yet, such human activities also can imperil these habitats and undermine the ecosystem services they provide to people. Cumulative risk assessment provides an analytical framework for synthesizing the influence of multiple stressors across habitats and decision-support for balancing human uses and ecosystem health. To explore cumulative risk to habitats in the U.S. Northeast and Mid-Atlantic Ocean Planning regions, we apply the open-source InVEST Habitat Risk Assessment model to 13 habitats and 31 stressors in an exposure-consequence framework. In doing so, we advance the science priorities of EBM and both regional planning bodies by synthesizing the wealth of available data to improve our understanding of human uses and how they affect marine resources. We find that risk to ecosystems is greatest first, along the coast, where a large number of stressors occur in close proximity and secondly, along the continental shelf, where fewer, higher consequence activities occur. Habitats at greatest risk include soft and hard-bottom nearshore areas, tidal flats, soft-bottom shelf habitat, and rocky intertidal zones—with the degree of risk varying spatially. Across all habitats, our results indicate that rising sea surface temperatures, commercial fishing, and shipping consistently and disproportionally contribute to risk. Further, our findings suggest that management in the nearshore will require simultaneously addressing the temporal and spatial overlap as well as intensity of multiple human activities and that management in the offshore requires more targeted efforts to reduce exposure from specific threats. We offer a transparent, generalizable approach to evaluating cumulative risk to multiple habitats and illustrate the spatially heterogeneous nature of impacts along the eastern Atlantic coast and the importance of spatial scale in estimating such impacts. These results offer a valuable decision-support tool by helping to constrain the decision space, focus attention on habitats and locations at the greatest risk, and highlight effect management strategies.
The highly GABARAP specific rat monoclonal antibody 8H5 visualizes GABARAP in immunofluorescence imaging at endogenous levels (2019)

The determination of unique functions of GABARAP (gamma-aminobutyric acid type A receptor-associated protein), a member of the highly conserved protein family of mammalian autophagy-related 8 protein (mATG8), within diverse cellular processes remains challenging. Because available anti-GABARAP antibodies perform inadequate, especially within various microscopy-based applications, we aimed to develop an antibody that targets GABARAP but not its close orthologs. Following the latest recommendations for antibody validation including fluorescence protein tagging, genetic and orthogonal strategies, we characterized the resulting anti-GABARAP (8H5) antibody during confocal immunofluorescence imaging in-depth. We compared the antibody staining pattern with that obtained for fluorescence protein tagged GABARAP, GABARAPL1 or GABARAPL2 each ectopically expressed in GABARAP knockout cells. Furthermore, we imaged cells expressing all mATG8 family members at endogenous levels and checked GABARAP knockout cells for unspecific staining under fed or macroautophagy-inducing conditions. Finally, we simultaneously stained cells for endogenous GABARAP and the common autophagosomal marker LC3B. Summarized, the presented antibody shows high specificity for GABARAP without cross-reactivity to other mATG8 family members in immunofluorescence imaging making it a valuable tool for the identification of unique GABARAP functions.
Graph Mining Techniques for Networking Applications (2010)

Computer networks are inherently graphical in structure, since they contain multiple geographically distributed nodes, which are connected by communication links. In many cases, such as large military networks, this also leads to a network-centric view of the data. This naturally leads to an information network representation of the data. In information networks, the nodes represent the different elements of information, and the links represent the logical relationships between them. An even higher layer of logical organization is a social network, in which the nodes correspond to the different entities in the network, and the links correspond to the interactions. The common element among the different kinds of networks which are encountered in practical network-centric representation of the data is that they can all be represented in the form of a structural graph. This structural behavior can be used in order to glean different kinds of practical insights. This chapter will provide an overview of these different graph mining techniques and their applications to the various kinds of networks.
Fiber Bragg grating sensor system based on resonance Fourier domain mode-locked laser (2015)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text J. Park, B. K. Choi, I. S. Choi, and M. Y. Jeon, "Fiber Bragg grating sensor system based on resonance Fourier domain mode-locked laser," in Asia Communications and Photonics Conference 2015, C. Lu, J. Luo, Y. Ji, K. Kitayama, H. Tam, K. Xu, P. Ghiggino, and N. Wada, eds., OSA Technical Digest (online) (Optica Publishing Group, 2015), paper ASu2A.63. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
COMBUSTION ISSUES AND APPROACHES FOR CHEMICAL MICROTHRUSTERS (2007)

In the present paper, results from the development of a meso/micro scale liquid-propellant thruster are reported along with a discussion of the usage of microthrusters in small spacecraft and the effects of downsizing on combustion performance. In particular, combustion of liquid nitromethane in a thruster combustion chamber with a volume of 108 mm3 and diameter of 5 mm was experimentally investigated. The meso-scale combustor utilized a vortex combustion concept, in which monopropellants were injected tangentially from the front end of the cylindrical combustor and combustion products exited the chamber tangentially at the other end. Although combustion was achievable at pressures as low as 150 psig, pressures as high as 350 psig were required for complete combustion. Combustion at atmospheric pressure was achieved only with the addition of small quantities of oxygen. To complement the experiments, a comprehensive numerical analysis was developed to study the combustion of liquid monopropellant in a small-volume vortex chamber based on a two-phase flow analysis using the level-set approach. The model allows for a detailed investigation of the liquid-film motion and gas-phase flow development. Combustion chambers and nozzles were fabricated from ceramics (alumina) because of the high flame temperatures required to sustain gas-phase reactions. Operation of thrusters on hydrogen-air-oxygen mixtures at a combustion chamber pressure of 40 psig was demonstrated to produce characteristic velocity efficiencies of approximately 90%.
Cognitive Multiuser MIMO in Spectrum Sharing Environment with Antenna Correlation over Nakagami-m Fading (2014)

In this paper, we examine the impact of antenna correlation on transmit antenna selection with receive maximal ratio combining (TAS/MRC) in multiple-input multiple-output multiuser network (MUN-MIMO) with single source, M destinations with underlay spectrum sharing over Nakagami-m fading environment. The secondary network under consideration is equipped with multiple correlated antennas at each node. The primary networks composed of L primary users (PUs) equipped with multiple correlated antennas. For the underlay spectrum sharing transmission, the transmit power condition of the proposed MU spectrum-sharing system is limited by peak interference temperature limit on the primary networks and the maximum transmission power at the secondary network. In particular, we derive an exact expression for the outage probability and SER of the proposed system. To gain further insights, simple asymptotic expression for the outage probability and SER are provided to obtain the achievable diversity order and coding gain of the system.
Structural dynamic properties of pentahaptocyclopentadienylmetal dicarbonyl dimers (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural dynamic properties of pentahaptocyclopentadienylmetal dicarbonyl dimersJ. G. Bullitt, F. A. Cotton, and T. J. MarksCite this: Inorg. Chem. 1972, 11, 4, 671–676Publication Date (Print):April 1, 1972Publication History Published online1 May 2002Published inissue 1 April 1972https://pubs.acs.org/doi/10.1021/ic50110a001https://doi.org/10.1021/ic50110a001research-articleACS PublicationsRequest reuse permissionsArticle Views655Altmetric-Citations100LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Identification of novel positive allosteric modulators and null modulators at the GABA A receptor α+β− interface (2013)

Pyrazoloquinolinones and pyrazolopyridinones represent the first prototype of drug candidates mediating benzodiazepine like modulatory effects via the α+β-interface of GABAA receptors. The discovery of null modulators acting as inhibitors of the plus modulators provides a highly useful tool for the discovery of additional classes of compounds that can modulate GABAA receptors via this site, which may lead to novel therapeutic principles.
Effect of composition on the pressure-driven ferroelectric to antiferroelectric phase transformation behavior of (Pb0.97La0.02)(Zr1−x−ySnxTiy)O3 ceramics (2014)

Power can be generated by rapidly driving a poled ferroelectric material through a ferroelectric to antiferroelectric phase transformation. The power generated depends on the maximum remnant polarization that can be obtained in the ferroelectric state and the minimum dielectric permittivity that can be obtained in the antiferroelectric state. In this study, the effect of composition on these properties was measured for compositions in the (Pb0.97La0.02)(Zr1−x−ySnxTiy)O3 system. Specimens were fabricated and characterized in the ferroelectric and antiferroelectric state under hydrostatic loading. The results are discussed in terms of their impact on an energy harvesting cycle that utilizes a ferroelectric to antiferroelectric phase transformation. The calculated maximum theoretical energy density based on the measurements was 14.5 J/cm3.
Ceramic Damping Coatings: Evaluating Their Effectiveness and Predicting Added Damping (2009)

This chapter contains sections titled: Abstract Introduction Evaluating Damping Effectiveness Damping Mechanism of Hard Coatings Mixed Numerical Experimental Procedure for Extracting Modulus of Elasticity and Loss Factor of Ceramic Coatings FE Prediction Routine for Damping Coatings Tests of a Coated Plate at the Rotating Damping RIG Comparison of Predicted Against Measured Results for Mode 1F Discussion and Conclusions Suggestions for Further work References Acknowledgements Figures
XDDS: A scalable guard-agnostic cross domain discovery service (2010)

As both the Department of Defense and the Intelligence Community are moving toward service-oriented architecture (SOA), it is important to ensure that SOA-based systems can operate and exchange classified information across domain boundaries in support of support net-centric missions. The interplay between SOA and cross domain solutions (CDS) raise a number of challenges that are grounded in the inherent mismatch between core SOA principles, such as loose coupling, composabil-ity, and discoverability, and current CDS technologies and certification and accreditation processes in use today. The Cross Domain Discovery Service (XDDS) described in this paper describes an architecture and design for extending service discovery, a core SOA functionality, across domain boundaries. The resulting services and protocols provide access to service information across security domains in a secure, guard-agnostic, scalable, and flexible way that is amenable to certification and accreditation.
Global Communications Newsletter (2022)

at the David Intercontinental Hotel in Tel Aviv, Israel. The fi rst two days of the conference included the plenary sessions together with eight parallel sessions, while the third day was reserved for short courses and workshops in six parallel sessions as well as an additional two plenary sessions. In spite of the COVID-19 situation, the live conference was attended by more than 1200 engineers, academics, and technical developers.
Enhancing estimation accuracy by applying cross-correlation image tracking to self-sensing including evaluation on a low saliency ratio machine (2016)

Image tracking self-sensing, which utilizes cross-correlation to detect the rotor position by evaluating the orientation of the current image across a full injection cycle can enhance estimated accuracy and improve tolerance to noise. Cross-correlation over a full injection cycle replaces the classical heterodyning demodulation used in traditional point-tracking methods and is known to produce significant harmonic content. Image tracking mitigates dynamic degradation since there is no longer a need for low pass filtering of the harmonic content. Cross-correlation also handles complex images well. This paper will document how by the careful consideration of the machine properties at an operating point, details of the current response can be used to generate a complex image over the full injection cycle. This paper will also show how cross-correlation of the sampled image over each full injection cycle with this detailed model, allows for a more accurate estimate of position when compared to traditional point-tracking methods. These methods are evaluated experimentally on a low saliency ratio SPM and compared to classical rotating and pulsating point-tracking HFI methods.
X-ray magnetic spectroscopy of MBE-grown Mn-doped Bi2Se3 thin films (2014)

We report the growth of Mn-doped Bi2Se3 thin films by molecular beam epitaxy (MBE), investigated by x-ray diffraction (XRD), atomic force microscopy (AFM), SQUID magnetometry and x-ray magnetic circular dichroism (XMCD). Epitaxial films were deposited on c-plane sapphire substrates by co-evaporation. The films exhibit a spiral growth mechanism typical of this material class, as revealed by AFM. The XRD measurements demonstrate a good crystalline structure which is retained upon doping up to ∼7.5 atomic-% Mn, determined by Rutherford backscattering spectrometry (RBS), and show no evidence of the formation of parasitic phases. However an increasing interstitial incorporation of Mn is observed with increasing doping concentration. A magnetic moment of 5.1 μB/Mn is obtained from bulk-sensitive SQUID measurements, and a much lower moment of 1.6 μB/Mn from surface-sensitive XMCD. At ∼2.5 K, XMCD at the Mn L2,3 edge, reveals short-range magnetic order in the films and indicates ferromagnetic order below 1.5 K.
GLASS-LIKE CARBON SPUTTERING TARGET FOR PROTECTIVE LAYER (1989)

Various protective carbon layers deposited on the surface of CoNi magnetic layer on the Cr/NiP pretreated aluminium alloy substrate are studied in view of wear resistance. Microstructure of the carbon layer is controlled by varying sputtering conditions and targets, especially glass-like carbon target. It is formed that the most wear resistive layer has an amorphous structure characterized by a single 1550cm-1 peak in the Raman spectrum, while the other layers have ordinary graphite spectrum, with two peaks at 1360cm-1 and 1580cm-1.
Altered gene expression in cloned piglets (2008)

Studies on cloned pigs are scant compared with those in mice and cattle. Expression profiles of cloned pig embryos on full-term cloned pigs are even more limited owing to the limited availability of DNA microarray technology in the pig. We have conducted expression profile comparisons between pigs from somatic cell nuclear transfer and pigs from conventional breeding at birth and 1 month of age. Differentially expressed genes that are subjected to DNA methylation were also examined for their DNA methylation status. These data will be presented in the 2009 Annual Meeting of the International Embryo Transfer Society in San Diego. In the present review, we focus on summarising existing findings on epigenetic and other changes in cloned embryo, cloned pigs and their offspring by conventional breeding.
Improvement of Perovskite Solar Cell Efficiency through PLA Additive Induced Boundary Passivation : With Application of Machine Learning in Crystal Image Analysis (2018)

Perovskite solar cells are an extremely promising photovoltaic technology due to their rapid improvement in power conversion efficiency (PCE) in recent years. Polylactic acid (PLA) is a biodegradable polyester plastic that is used in additive manufacturing. In this study, we used two PLA additives, 30K PLA and 16K PLA, to improve the performance of perovskite solar cells. In particular, we show that these PLA additives unanimously increase the PCE of perovskite solar cells across various concentrations and molecular weights. Additionally, because perovskite crystal size is positively correlated with cell efficiency, we developed a machine learning algorithm to autonomously compute size distributions of PLA-modified perovskite crystals from SEM images. This procedure showed that both the 30K and 16K PLA increased the average size of the crystal grains (p<; 0.05). The reason for the increased performance and crystal size are that the PLA forms complexes with excess PbI <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , with PLA at the core and a PbI <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> surrounding. These complexes passivate the boundaries between crystal grains, decreasing the number of trapped or dissoluted excitons and redirecting them in the direction of the current. The complexes likely also decrease the interfacial tension between crystal grains, resulting in crystal sizes which are up to 226% larger. By varying only concentration or only molecular weight, we discovered that there existed an optimal concentration and an optimal molecular weight of around 0.3 mg/mL and 16,000 amu respectively. We identified competing factors that would yield this trend: the aforementioned positive effects of the PLA, and the negative effects of nonideality of the JV curve (and consequences) and poorer conductivity. Given the observed improvement in efficiency of up to 17.5%, these results demonstrate that PLA additives are a novel and promising method of improving the performance of perovskite solar cells.
New Methods for the Synthesis of ArPdL2I (L = Tertiary Phosphine) Complexes (1996)

Organopalladium ArPdL2I (L = tertiary phosphine) complexes (1) can be synthesized in one step from the precursors Pd2(dba)3·C6H6 (2) (dba = t,t-dibenzylideneacetone) and (η3-allyl)PdCp (3) (Cp = η5-cyclopentadienide). Two advantages over previous synthetic methods are that this route requires only stoichiometric amounts of phosphine and that the desired complexes are easily isolated from reaction byproducts. The scope and generality of these reactions are investigated, and the synthesis of a number of new organic- and water-soluble complexes utilizing this methodology is discussed. Improved syntheses of water-soluble ligands P(C6H5)2(4-SO3KC6H4) (5) and As(C6H5)2(4-SO3KC6H4) (6) are presented as well.
Therapeutic effects of artesunate in hepatocellular carcinoma (2014)

These findings indicate that artesunate could offer a new approach to the therapy of hepatocellular carcinoma. Clinical trials with artesunate as monotherapy or in combination with current hypoxia-inducing approaches are necessary.