gebhart/patrepeval huggingface dataset:
Synthetic aperture radar (SAR) imaging for a borehole impulse radar (1995)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1995Synthetic aperture radar (SAR) imaging for a borehole impulse radarAuthors: Thomas L. MarzettaCharles P. PlumMichael L. OristaglioTarek M. HabashyDavid R. MarianiRichard W. GaylorThomas L. MarzettaNichols Research Corporation, Charles P. PlumNichols Research Corporation, Michael L. OristaglioSchlumberger‐Doll Research, Tarek M. HabashySchlumberger‐Doll Research, David R. MarianiSchlumberger‐Doll Research, and Richard W. GaylorSchlumberger‐Doll Researchhttps://doi.org/10.1190/1.1887485 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InReddit Permalink: https://doi.org/10.1190/1.1887485FiguresReferencesRelatedDetails SEG Technical Program Expanded Abstracts 1995 ISSN (print):1052-3812 ISSN (online):1949-4645 Copyright: 1995 Pages: 1566 publication data© 1995 Copyright © 1995 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished Online: 10 Feb 2005 CITATION INFORMATION Thomas L. Marzetta, Charles P. Plum, Michael L. Oristaglio, Tarek M. Habashy, David R. Mariani, and Richard W. Gaylor, (1995), "Synthetic aperture radar (SAR) imaging for a borehole impulse radar," SEG Technical Program Expanded Abstracts : 242-245. https://doi.org/10.1190/1.1887485 Plain-Language Summary PDF DownloadLoading ...
A new, delay-line-discriminator-based, hybrid RF/digital phase noise cancellation technique (2013)

A new, hybrid RF/digital phase noise cancellation technique is presented. The proposed phase noise cancellation technique estimates the phase noise using an RF delay-line-discriminator (DLD), digitizes the DLD output, performs proper digital signal processing (DSP) and then compensates for the phase noise at the digital baseband. This new technique is applicable to both transmitter and receiver and is independent of the modulation and waveform. As part of the DSP, an adaptive linear prediction filter (ALPF) is applied to compensate the analog delay associated with the DLD, low-pass filters, and data conversion. Such delay compensation enhances the phase noise cancellation bandwidth. 30 dB of phase noise cancellation is achieved in simulation using realistic phase noise and component models.
The Importance of Selectivity in Ammoxidation Catalysis (2007)

I have had the pleasure to meet Sir John about 30 years ago when I was at SOHIO (Cleveland, OH, USA), and where he was invited to give a series of lectures. A few years later, at the Discussions of the Faraday Society in Nottingham, England (1981), he came to my rescue when I proposed in my lecture ...
First-Principles Characterization of Potassium Intercalation in Hexagonal 2H-MoS2 (2012)

Periodic density functional theory calculations were performed to study the structural and electronic properties of potassium intercalated into hexagonal MoS2 (2H-MoS2). Metallic potassium (K) atoms are incrementally loaded in the hexagonal sites of the interstitial spaces between MoS2 layers of the 2H-MoS2 bulk structure generating KxMoS2 (0.125 ≤ x ≤ 1.0) structures. To accommodate the potassium atoms, the interstitial spacing c parameter in the 2H-MoS2 bulk expands to 15.871 Å in K0.125MoS2. The second lowest potassium loading concentration (K0.25MoS2) results in the largest interstitial spacing expansion (to c = 16.617 Å). Our calculations show that there is a small gradual contraction of the interstitial spacing as the potassium loading increases with c = 14.785 Å for KMoS2. This interstitial contraction is correlated with an in-plane expansion of the MoS2 layers, which is in good agreement with experimental X-ray diffraction (XRD) measurements. The electronic analysis shows that potassium readily donates its 4s electron to the conduction band of the MoS2, and is largely ionic in character. As a result of the electron donation, the KxMoS2 system changes from a semiconductor to a more metallic system with increasing potassium intercalation. For loadings 0.25 ≤ x ≤ 0.625, triangular Mo–Mo–Mo moieties are prominent and tend to form interlayer rhombitrihexagonal tessellated patterns. Intercalation of H2O molecules that solvate the K cations is likely to occur in catalytic conditions. The inclusion of two H2O molecules per K atom in the K0.25MoS2 structure shows good agreement with XRD measurements.
Identifying problematic drugs based on the characteristics of their targets (2015)

Identifying promising compounds during the early stages of drug development is a major challenge for both academia and the pharmaceutical industry. The difficulties are even more pronounced when we consider multi-target pharmacology, where the compounds often target more than one protein, or multiple compounds are used together. Here, we address this problem by using machine learning and network analysis to process sequence and interaction data from human proteins to identify promising compounds. We used this strategy to identify properties that make certain proteins more likely to cause harmful effects when targeted; such proteins usually have domains commonly found throughout the human proteome. Additionally, since currently marketed drugs hit multiple targets simultaneously, we combined the information from individual proteins to devise a score that quantifies the likelihood of a compound being harmful to humans. This approach enabled us to distinguish between approved and problematic drugs with an accuracy of 60-70%. Moreover, our approach can be applied as soon as candidate drugs are available, as demonstrated with predictions for more than 5000 experimental drugs. These resources are available at http://sourceforge.net/projects/psin/.
Packet Throughput Analysis of Static and Dynamic TDD in Small Cell Networks (2017)

We develop an analytical framework for the perfor- mance comparison of small cell networks operating under static time division duplexing (S-TDD) and dynamic TDD (D-TDD). While in S-TDD downlink/uplink (DL/UL) cell transmissions are synchronized, in D-TDD each cell dynamically allocates resources to the most demanding direction. By leveraging stochastic geom- etry and queuing theory, we derive closed-form expressions for the UL and DL packet throughput, also capturing the impact of random traffic arrivals and packet retransmissions. Through our analysis, which is validated via simulations, we confirm that D-TDD outperforms S-TDD in DL, with the vice versa occurring in UL, since asymmetric transmissions reduce DL interference at the expense of an increased UL interference. We also find that in asymmetric scenarios, where most of the traffic is in DL, D-TDD provides a DL packet throughput gain by better controlling the queuing delay, and that such gain vanishes in the light-traffic regime.
Cyclic delay transmission achieves full diversity without (Pre)coding (2012)

Cyclic Delay Diversity (CDD) is a simple method that converts transmit antenna diversity into frequency selectivity, thus allowing simple operation and use of conventional receivers to capture the diversity. This paper shows that single-carrier CDD methods are capable of producing diversity without channel coding or linear precoding, and that this is made possible via the appropriate design and use of linear equalizers. At the heart of our result is the establishment of a functional equivalence between effective channels seen by the CDD MISO system and the cyclic-prefix SISO ISI system. Specifically, we show that in an M×1 CDD MSIO system, the MMSE receiver achieves maximum diversity for rate values R ≤ log L/M(ν+1)-1, where L is the data block length, R the spectral efficiency in b/s/Hz, and ν is the channel memory. The equivalence between the delay diversity (DD) system and a zero-padding single-carrier system can be also established (as long as the DD delay taps are carefully chosen) for which linear equalizers can achieve maximum diversity with no constraint on rate.
[Animal circoviruses and associated diseases]. (2005)

Animal circoviruses belong to the Circovirus genus of the Circoviridae family. Nowadays, only swine and birds were identified as circovirus hosts. Circoviruses have a single-stranded circular genome of approximately 2000 nucleotide long. DNA of these viruses possesses : (i) a nonanucleotide sequence essential for replication, flanked by inverted repeat sequences, a palindrome that has the potential to form a stem-loop structure and (ii) two major ORFs, located on the viral and complementary strands, which encode respectively the replication-associated protein (Rep) and the capsid protein (Cap). All the circoviruses described at the present time, except porcine circovirus of type 1, are associated with immunosuppressive or immunodepressive diseases. Histopathological lesions such as cytoplasmic inclusions of virus in histiocytic cells and T and B lymphocyte depletion in lymphoid organs, are commonly noticed. No medical prophylaxis of circovirus infections is currently available.
A nanoparticle priming agent reduces cellular uptake of cell-free DNA and enhances the sensitivity of liquid biopsies (2023)

Liquid biopsies are enabling minimally invasive monitoring and molecular profiling of diseases across medicine, but their sensitivity remains limited by the scarcity of cell-free DNA (cfDNA) in blood. Here, we report an intravenous priming agent that is given prior to a blood draw to increase the abundance of cfDNA in circulation. Our priming agent consists of nanoparticles that act on the cells responsible for cfDNA clearance to slow down cfDNA uptake. In tumor-bearing mice, this agent increases the recovery of circulating tumor DNA (ctDNA) by up to 60-fold and improves the sensitivity of a ctDNA diagnostic assay from 0% to 75% at low tumor burden. We envision that this priming approach will significantly improve the performance of liquid biopsies across a wide range of clinical applications in oncology and beyond.
Integrated Impactor/Detector for a High-Throughput Explosive-Trace Detection Portal (2012)

The design of a very-high-flow-rate inertial particle impactor with integrated sampling for use in a walk-through explosive-trace detection portal is presented. This impactor is designed to collect particles of explosives from the aerodynamic wake of a walking subject, which requires a sampling capability of ~ 1m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> /s and must reliably collect particles of ≥ 5-μm diameter. An impactor cross-section of 0.3 × 0.3 m was used, with three linear slot nozzles and corresponding impactor blades. The central impactor blade has a rotating impaction surface with an integrated heater for automated thermal desorption of the impacted material. An ion mobility spectrometer is used to interrogate the desorbed vapor for trace explosives detection. The process of sampling a subject and interrogating its aerodynamic wake for explosives requires about 8 s totally, allowing very-high throughput sampling for security-screening purposes.
Temporal Patterns of Ventricular Tachyarrhythmia Recurrences Follow a Weibull Distribution (2005)

In most patients with >or=3 ICD detections, the recurrence pattern of treated ventricular tachyarrhythmia detections are clustered and can be described by a Weibull distribution. The proportion of patients with multiple detections in a 24-hour period declines in a linear fashion as the number of events in 24 hours increases from 2 to 10 events.
Buying Time for Resource-Bounded Planning (1997)

To react appropriately in hard real-time environments, a system must either employ fast dynamic planning or recall a pre-built reactive response. For complex problems, real-time, accurate dynamic planning may be impossible, and the complete set of possible reactions may be too large to build and store in advance. In this paper, we propose combining offline and online planning such that a set of offline plans are built and stored to maximize the amount of time available for any subsequent online planning. We explore this concept in CIRCA, the Cooperative Intelligent Real-time Control Architecture, which has concentrated on guaranteeing failure avoidance via a combination of planning, scheduling, and real-time plan execution. We are in the process of implementing a plan cache which will increase CIRCA&amp;apos;s overall likelihood of success in timeconstrained situations, and we illustrate potential gains from these modifications using a simple example from the fully-automated aircraft domain. In...
A Method of Fabricating Bump-Less Interconnects Applicable to Wafer-Scale Flip-Chip Bonding (2008)

A chemical flip-chip bonding method by electroless plating process has been developed. This method positively utilizes so-called "bridge" phenomenon between metal pads in electroless Ni-B plating, and enables bump-less interconnect without loading and/or heating at lower temperature (60°C). The interconnect behavior was examined using test chips and substrates with various pad-to-pad configurations. The result confirmed that effective pad width and a ratio of pad pitch to pad width determine the completeness of the interconnection under the condition that distance between facing pads are sufficiently close. A potential of improved method was also demonstrated for fabricating finer pitch flip-chip interconnect with a minimum pad-pitch of 20 ¿m.
One Hundred Year Study on Artificial Intelligence: Reflections and Framing (2014)

The One Hundred Year Study on Artificial Intelligence (AI) has its roots in a one-year study on Long-term AI Futures that we commissioned during my term of service as president of the Association for the Advancement of Artificial Intelligence (AAAI) in 2008-2009. The presidential panel was divided into three groups, with one team exploring opportunities and concerns arising in the near term, another team exploring more speculative long-term outcomes, and a third team taking a special focus on legal and ethical challenges that might come to the fore with the construction and fielding of computational systems with one or more abilities to perceive, learn, reason, and act in the world. The panel was asked to reflect about the opportunities ahead, as well as to consider uncertainties and potential “rough edges” that might come to the fore, and to highlight topics that would require additional study. For potential concerns, the group was asked to reflect about the value of proactive efforts to mitigate concerns and to ensure good outcomes.
Rewards with Negative Examples for Reinforced Topic-Focused Abstractive Summarization (2021)

We consider the problem of topic-focused abstractive summarization, where the goal is to generate an abstractive summary focused on a particular topic, a phrase of one or multiple words. We hypothesize that the task of generating topic-focused summaries can be improved by showing the model what it must not focus on. We introduce a deep reinforcement learning approach to topic-focused abstractive summarization, trained on rewards with a novel negative example baseline. We define the input in this problem as the source text preceded by the topic. We adapt the CNN-Daily Mail and New York Times summarization datasets for this task. We then show through experiments on existing rewards that the use of a negative example baseline can outperform the use of a self-critical baseline, in ROUGE, BERTSCORE, and human evaluation metrics.
Improving Electrodeposition of Mg through an Open Circuit Potential Hold (2015)

We used in situ X-ray diffraction, XPS, SEM, and electrochemical methods to interrogate the mechanism of Mg electrodeposition from PhMgCl/AlCl3 (APC) and EtMgCl electrolytes. An open circuit potential (OCP) pause following Mg deposition led to retained enhancement of Mg deposition and stripping kinetics along with lowered overpotentials for both. In situ X-ray diffraction demonstrated that the OCP pause led to a more polycrystalline deposit relative to that without the pause, while SEM presented micrographs that showed smaller deposits with an OCP hold. The improvement is attributed to an “enhancement layer” that formed on the electrode during the OCP hold. Analysis of XPS data suggests that the “enhancement layer” consists of Mg and Cl retained on the electrode surface, possibly following electrode depassivation.
The expression level of HJURP has an independent prognostic impact and predicts the sensitivity to radiotherapy in breast cancer (2010)

HJURP mRNA level is a prognostic factor for disease-free and overall survival in patients with breast cancer and is a predictive biomarker for sensitivity to radiotherapy.
Methods and techniques for measuring and improving data center best practices (2008)

Here we present a novel, measurement-based method for characterizing and improving the energy efficiency of a data center (DC). The technique not only yields a clear set of measurement-based best practices metrics, but also provides clear guidance to a DC manager to substantially improve the DC energy efficiency. We describe a technology which exploits the superiority of fast and massive parallel data collection using the Mobile Measurement Technology (MMT) [1] to drive towards quantitative, measurement-driven DC best practices implementation. A large representative raised-floor DC is mapped by the MMT methodology readily yielding the DC layout, very detailed 3D temperature distributions, flows and other relevant physical parameters of the specific facility. The data is used to calculate key metrics (horizontal and vertical hotspots, targeted air flow, plenum temperature, air conditioning unit utilization and flow levels). These metrics provide insights into the sources of energy inefficiencies of the current DC setup, and systematically guide DC managers to improve various best practice aspects in the specific DC. It is shown that significant energy reductions can be achieved utilizing the above described best practices methodology.
Non-Invasive Vascular Elastography as a One-Step Imaging Technique to Evaluate Early Vascular Changes in Children Compared to B-Mode-Based Intima-Media Thickness Technique : A Validation Study Using Inter- and Intra-Rater Reliability (2022)

<b>Background:</b> Childhood obesity is linked to higher adult mortality and morbidity from atherosclerosis. It is primordial to detect at-risk children earlier-on to prevent disease progression. Carotid intima-media thickness (IMT) is a subclinical radiological marker for early atherosclerosis. B-mode ultrasound is a known technique to assess IMT, but no gold standard technique exists in children. Non-invasive vascular elastography (NIVE) using speckle statistics is an innovative alternative to evaluate IMT and adds by providing translation, strain and shear strain measurements. Validation studies for both techniques lack in children. <b>Purpose:</b> Validate the reproducibility of the 2 techniques in Canadian children. <b>Methods:</b> We conducted a prospective study where anthropometry, blood pressure, IMT and elastography were measured. Six operators obtained 2 measurements for both carotid arteries using both techniques, for a total of 720 measurements. Inter- and intra-class correlation coefficients (ICC) were calculated for each measurement technique and elastography parameters. <b>Results:</b> 30 participants (13.0 ± 1.26 years, 17 girls) were recruited. Twelve were overweight. No significant difference was found in mean IMT between weight groups for either technique (<i>P</i> = .15 and <i>P</i> = .60). We found excellent inter- (ICC = .98 [95% Confidence Interval (CI): .97; .99]) and intra- (ICC = .90-.93) operator reliability for the B-mode technique, and good inter (ICC = .70 [95% CI: .47; .85]) and intra- (ICC = .71-.91) operator reliability for the NIVE-based technique. Poor reliability was found between techniques (ICC = .30 [95% CI: -.31; .65). For elastography parameters, translation was the most reliable (ICC = .94-.95). <b>Conclusion:</b> IMT measurement is reproducible in children but not between techniques. NIVE gives the advantage of evaluating elastography.
Development of Industrial SFF System Using a New Selective Dual-Laser Sintering Process (2006)

In order to develop more elaborate and speedy system for large objects than existing selective laser sintering (SLS), this study applies a new selective dual-laser sintering process. It contains a 3-axis dynamic focusing scanner system for scanning large area instead of the existing fθ lens. As sintering parameters, the sintering temperature, the laser beam power and the layer thickness have a great influence on sintering of the polymer and metal powder. This paper will address the development of a solid freeform fabrication (SFF) system employing the dual laser system. Experiments were performed to evaluate the effect of a scanning path and to fabricate the large-sized object.
HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease (2017)

Peripheral nerve axons require a well-organized axonal microtubule network for efficient transport to ensure the constant crosstalk between soma and synapse. Mutations in more than 80 different genes cause Charcot-Marie-Tooth disease, which is the most common inherited disorder affecting peripheral nerves. This genetic heterogeneity has hampered the development of therapeutics for Charcot-Marie-Tooth disease. The aim of this study was to explore whether histone deacetylase 6 (HDAC6) can serve as a therapeutic target focusing on the mutant glycyl-tRNA synthetase (GlyRS/GARS)-induced peripheral neuropathy. Peripheral nerves and dorsal root ganglia from the C201R mutant Gars mouse model showed reduced acetylated α-tubulin levels. In primary dorsal root ganglion neurons, mutant GlyRS affected neurite length and disrupted normal mitochondrial transport. We demonstrated that GlyRS co-immunoprecipitated with HDAC6 and that this interaction was blocked by tubastatin A, a selective inhibitor of the deacetylating function of HDAC6. Moreover, HDAC6 inhibition restored mitochondrial axonal transport in mutant GlyRS-expressing neurons. Systemic delivery of a specific HDAC6 inhibitor increased α-tubulin acetylation in peripheral nerves and partially restored nerve conduction and motor behaviour in mutant Gars mice. Our study demonstrates that α-tubulin deacetylation and disrupted axonal transport may represent a common pathogenic mechanism underlying Charcot-Marie-Tooth disease and it broadens the therapeutic potential of selective HDAC6 inhibition to other genetic forms of axonal Charcot-Marie-Tooth disease.
Crosstalk challenge and mitigation through strategic pin placement for 25Gbps and beyond (2015)

In high density, high speed Serdes interconnect designs, inappropriate pin placement can lead to differential crosstalk violation. How to relatively compare the crosstalk level due to various pin placements, and estimate its effect on the whole system without time consuming simulation is critical. This paper introduces a simple method to estimate the relative differential crosstalk due to various pin distributions. The effectiveness of this method is investigated using commercial 3D electromagnetic software. How the surrounding environment can affect the crosstalk level is also studied in this article.