gebhart/patrepeval huggingface dataset:
An Analysis of Preventive Methods for Baseball-Induced, Chest Impact Injuries (1992)

The purpose of this study was to evaluate a nonliving laboratory model for the low-mass, high-velocity chest impact scenario associated with baseball impact deaths in children. A second purpose was to evaluate current protective sports equipment that could favorably modify the incidence of chest impact fatalities that occur in baseball. We studied the effects of baseball impact to the chest of swine as well as in two modified crash dummies. The animal protocol was used initially in pilot tests of protective equipment, during which soft core baseballs and generic closed cell foam chest protection were studied. In the animal model, when chest protectors, utilized alone or in combination, were compared with the effects of hard ball impact on the unprotected chest, only minor reductions were found in the incidence of cardiac arrythmias. A child crash dummy and a fifth percentile female Hybrid III crash dummy were then utilized in the biomechanical testing of chest protectors. The internal deflection and viscous response values obtained from the Hybrid III dummy showed minimal reduction in response when chest protectors were used compared to the unprotected dummy. Using a generic closed cell foam chest protector impacted by a standard hard baseball, the impact force increased between 6 and 43%, and the momentum delivered increased between 10 and 15%. When a softer core baseball was used with generic closed cell foam protection, the force measured increased between 15 and 58%, and the momentum delivered increased between 14 and 18%. Impact tests using the standard hardball and the softer core baseball on the unprotected chest showed minimal differences in the viscous response measured. Closed cell foam protectors, including ABS plastic hard shell-covered generic closed cell foam, had only a marginal effect in reducing levels of chest viscous response. We conclude that the different types of softer core baseballs utilized in this study have no appeciable protective effect and in some cases may exacerbate the impact force of a baseball to the chest. We also conclude that the chest protectors and the various types of chest protector materials studied have minimal protective effects and may also exacerbate the impact force to the chest. To date, no effective preventive approach has been developed to eliminate or reduce chest injuries from baseball impact in the pediatric population.
Trial Watch (2014)

The expression "adoptive cell transfer" (ACT) is commonly employed to indicate an immunotherapeutic regimen involving the isolation of autologous blood-borne or tumor-infiltrating lymphocytes, their selection/expansion/activation ex vivo, and their reinfusion into the patient, most often in the context of lymphodepleting pre-conditioning and in combination with immunostimulatory treatments. Optionally, the cellular material for ACT is genetically manipulated before expansion to (1) target specific tumor-associated antigens; (2) endogenously express immunostimulatory molecules; and/or (3) persist for long periods upon reinfusion. Consistent efforts have been dedicated at the amelioration of this immunotherapeutic regimen throughout the past decade, resulting in the establishment of ever more efficient and safer ACT protocols. Accordingly, the number of clinical trials testing ACT in oncological indications does not cease to increase. In this Trial Watch, we summarize recent developments in this exciting area of research, covering both high-impact studies that have been published during the last 12 months and clinical trials that have been launched in the same period to evaluate the safety and therapeutic potential of ACT in cancer patients.
Spatial Sound and Virtual Acoustics (2007)

1 Laboratory of Acoustics and Audio Signal Processing, Helsinki University of Technology, P.O. Box 3000, 02015 TKK, Finland 2Laboratoire de Communications Audiovisuelles 1, Institut de Systemes de Communication, Faculte Informatique et Communications, Ecole Polytechnique Federale de Lausanne (EPFL), 1015 Lausanne, Switzerland 3Digital Signal Processing Group, Philips Research Labs, 5656 Eindhoven, The Netherlands 4Telecommunications Software and Multimedia Laboratory, Helsinki University of Technology, P.O. Box 5400, 02015 TKK, Finland
Cloning and sequencing of the bacterioferritin gene of Brucella melitensis 16M strain (1995)

The 40 N-terminal amino acids of the 20 kDa antigen A2 from Brucella melitensis were sequenced and showed important similarities with 4 bacterioferrins. A monoclonal antibody raised against this antigen cross-reacted with Escherichia coli bacterioferritin. Hybridization of two sets of degenerate primers with B. melitensis HindIII-digested genomic DNA identified a 3.8 kb fragment. This fragment was shown to contain a bacterioferritin gene (bfr) encoding a 161-amino acid protein. The sequence of the Brucella bacterioferritin is 69% similar to that of E. coli, and many of the ferroxidase centre and haem-ligation residues are conserved.
Une méthodologie pour la conception intégrée des familles de produits et leur système d'assemblage (2001)

info:eu-repo/semantics/published
Interactions of DB75, a Novel Antimalarial Agent, with Other Antimalarial Drugs In Vitro (2008)

Pafuramidine is a novel orally active antimalarial. To identify a combination partner, we measured the in vitro antimalarial activities of the active metabolite, DB75, with amodiaquine, artemisinin, atovaquone, azithromycin, chloroquine, clindamycin, mefloquine, piperaquine, pyronaridine, tafenoquine, and tetracycline. None of the drugs tested demonstrated antagonistic or synergistic activity in combination with pafuramidine.
Modeling of Particle Fragmentation in Heterogeneous Olefin Polymerization Reactions, 2 (2005)

Abstract Summary: A two phase dynamic model is proposed here for the first time to describe the first stages of heterogeneous olefin polymerization and to improve predictions of particle morphology. Taking into account the solid and fluid phases, the two phase model allows for the calculation of the convective flux inside the growing polymer particle. Numerical simulations performed for both gas and slurry polymerizations show that the performances of the traditional diffusion model and of the proposed heterogeneous model are similar when mild polymerization conditions are considered, but may be very different when vigorous polymerization conditions are analyzed. It is shown that the development of convective flow inside the particle can exert a large influence on the course of the polymerization and on the final morphological characteristics of the polymer particle. When the initial catalyst particle contains inert material, it is also shown here that the inert material can contribute to a reduction of local reaction rates during particle breakup and, therefore, to a more uniform particle fragmentation. Schematic representation of a nascent polymer particle. magnified image Schematic representation of a nascent polymer particle.
MaX-DeepLab: End-to-End Panoptic Segmentation with Mask Transformers (2020)

We present MaX-DeepLab, the first end-to-end model for panoptic segmentation. Our approach simplifies the current pipeline that depends heavily on surrogate sub-tasks and hand-designed components, such as box detection, non-maximum suppression, thing-stuff merging, etc. Although these sub-tasks are tackled by area experts, they fail to comprehensively solve the target task. By contrast, our MaX-DeepLab directly predicts class-labeled masks with a mask transformer, and is trained with a panoptic quality inspired loss via bipartite matching. Our mask transformer employs a dual-path architecture that introduces a global memory path in addition to a CNN path, allowing direct communication with any CNN layers. As a result, MaX-DeepLab shows a significant 7.1% PQ gain in the box-free regime on the challenging COCO dataset, closing the gap between box-based and box-free methods for the first time. A small variant of MaX-DeepLab improves 3.0% PQ over DETR with similar parameters and M-Adds. Furthermore, MaX-DeepLab, without test time augmentation, achieves new state-of-the-art 51.3% PQ on COCO test-dev set. Code is available at https://github.com/google-research/deeplab2.
Hydroxyapatite Formation on a Novel Dental Cement in Human Saliva (2012)

Dental materials have to meet high standards regarding mechanical strength and handling properties. There is however only a limited amount of research that has been devoted to natural formation of hydroxyapatite (HA) in contact with the materials. The objective of the current investigation was to study the surface reactions occurring in human salvia on a novel dental cement. Ceramir Crown & Bridge, a bioceramic luting agent intended for permanent cementation of conventional oral prosthetics, was evaluated by immersing discs made from the cement in human saliva and phosphate buffered saline (PBS) for seven days, after which they were dried and analyzed. The analytical methods used in order to verify HA formation on the surface were grazing incidence X-ray diffraction (GI-XRD), scanning electron microscopy (SEM), and X-ray photoelectron spectroscopy (XPS). All results showed that HA was formed on the surfaces of samples stored in saliva as well as on samples stored in PBS. The possibility of a dental luting cement to promote natural formation of HA at the tooth interface increases the stability and durability of the system and could help prevent secondary caries.
Supplemental Figure S4 from Plasma KIM-1 Is Associated with Recurrence Risk after Nephrectomy for Localized Renal Cell Carcinoma: A Trial of the ECOG-ACRIN Research Group (E2805) (2023)

&lt;p&gt;Kaplan-Meier curves of disease-free survival by baseline KIM-1 stratified by nodal involvement at nephrectomy&lt;/p&gt;
A novel WLAN power amplifier adaptive loop based on delta-sigma non-linearity (2009)

The following discussion presents a novel technique of power management in TX 4G transmit path, capable of efficiently handling wide channel bandwidth and high peak-to-average-power-ratio (PAPR). It consists in a power adaptive closed loop, based on a switched multi-cell power amplifier (PA) core and a novel delta-sigma control loop topology. This work was carried out with a ST microelectronics SiGe technology.
Measurement of the Bottom Quark Contribution to Nonphotonic Electron Production inp+pCollisions ats=200  GeV (2010)

The contribution of B meson decays to nonphotonic electrons, which are mainly produced by the semileptonic decays of heavy-flavor mesons, in p + p collisions at √s=200 GeV has been measured using azimuthal correlations between nonphotonic electrons and hadrons. The extracted B decay contribution is approximately 50% at a transverse momentum of pT≥5 GeV/c. These measurements constrain the nuclear modification factor for electrons from B and D meson decays. The result indicates that B meson production in heavy ion collisions is also suppressed at high pT.
Dynamics of Electron Distribution Function in Multiple Mirror TRAP GOL-3 (2009)

Electron distribution function in experiments with intensive beam-plasma interaction is usually non-Maxwellian with high-energy tail. Details of such distribution function can clarify physics of the beam-plasma interaction process. The paper presents new experimental data from Thomson scattering measurements at GOL-3.
Automatic Identification of Environment Haptic Properties (1999)

Many applications can be imagined for a system that processes sensory information collected during telemanipulation tasks in order to automatically identify properties of the remote environment. These applications include generating model-based simulations for training operators in critical procedures and improving real-time performance in unstructured environments or when time delays are large. This paper explores the research issues involved in developing such an identification system, focusing on properties that can be identified from remote manipulator motion and force data. As a case study, a simple block-stacking task, performed with a teleoperated two-fingered planar hand, is considered. An algorithm is presented that automatically segments the data collected during the task, given only a general description of the temporal sequence of task events. Using the segmented data, the algorithm then successfully estimates the weight, width, height, and coefficient of friction of the two blocks handled during the task. This data is used to calibrate a virtual model incorporating visual and haptic feedback. This case study highlights the broader research issues that must be addressed in automatic property identification.
Highly available and fault-tolerant architecture guidelines for clustered middleware servers (2014)

The paper presents the result of an evaluation of the performance of different message broker system configurations, which lead to the construction of the specific architecture guidelines for such systems. The examples are provided for an exemplary middleware messaging server software - RabbitMQ, set in high availability - enabling and redundant configurations. Rabbit MQ is a message queuing system realizing the middleware for distributed systems that implements the Advanced Message Queuing Protocol. The scalability and high availability design issues are discussed and the possible cluster topologies and their impact is presented. Since HA and performance scalability requirements are in conflict, scenarios for using clustered RabbitMQ nodes and mirrored queues are interesting and have to be considered with specific workloads and requirements in mind. The results of performance measurements for some topologies are also reported in this article.
Unique antigen recognition by a herpesvirus-specific TCR-gamma delta cell. (1994)

TCR-gamma delta cells, a T cell subset present in the epithelial and lymphoid tissues, have been implicated in viral and bacterial infections. We have identified a TCR-gamma delta clone (TgI4.4) that, unlike TCR-alpha beta cells, recognizes a herpes simplex virus type 1 transmembrane glycoprotein, gI, in an MHC class I- and class II-independent fashion. The TCR of TgI4.4 is composed of rearranged V delta 8 (a V alpha 2 family member) and V gamma 1.2 variable genes, a heterodimeric pair not previously described. Furthermore, anti-V alpha 2 mAbs are sufficient to block recognition of the gI ligand. Strikingly, anti-gI Abs also are capable of blocking recognition, a phenomena that is very rare in TCR-alpha beta Ag recognition. Therefore, to dissect the mechanism involved in this unique form of Ag recognition, we constructed a mutant of gI, gIt, that lacks cell surface expression upon transfection into APCs. This form of gI was not sufficient for Ag presentation. In contrast, wild-type gI expressed in the Ag-processing mutant cell, RMA-S, is recognized by TgI4.4, suggesting that gI presentation occurs independently of classical Ag-processing pathways. In fact, through the use of a soluble recombinant gI molecule, gI-Ig, we show that TgI4.4 can recognize whole, unprocessed gI protein in the absence of any APCs. These results suggest that there exist alternate and novel forms of TCR Ag recognition, and that the TCR-gamma delta clone, TgI4.4, may represent a novel T cell subset that, during pathogenic challenge, may respond directly to Ags on the surfaces of bacteria and viruses.
Adaptive Digital Filtering as a Deconvolution Procedure in Multi-Input Chromatography (1992)

Journal Article Adaptive Digital Filtering as a Deconvolution Procedure in Multi-Input Chromatography Get access Somenath Mitra, Somenath Mitra Department of Chemical Engineering, Chemistry, and Environmental Science, New Jersey Institute of Technology, Newark, New Jersey 07102 Search for other works by this author on: Oxford Academic PubMed Google Scholar Tamal Bose Tamal Bose Department of Electrical Engineering, The Citadel, Charleston, South Carolina 29409 Search for other works by this author on: Oxford Academic PubMed Google Scholar Journal of Chromatographic Science, Volume 30, Issue 7, July 1992, Pages 256–260, https://doi.org/10.1093/chromsci/30.7.256 Published: 01 July 1992 Article history Received: 18 November 1991 Revision received: 28 April 1992 Published: 01 July 1992
Molecular Structure and Vaccine Design (1990)

Many bacterial clustered regularly interspaced short palindromic repeats (CRISPR)–CRISPR-associated (Cas) systems employ the dual RNA–guided DNA endonuclease Cas9 to defend against invading phages and conjugative plasmids by introducing site-specific ...Read More
Microwave-Triggered Surface Plasmon Coupled Chemiluminescence (2007)

We describe a high sensitivity and rapid sensing technology for the detection and determination of surface-bound proteins/enzymes and potentially even DNA/RNA. Low power microwave pulses are used to “trigger” chemiluminescence “on demand” at the tips of planar triangular structures. When the triangles are deposited on 40 nm thick continuous silver films with a spacer layer, the intense pulsed chemiluminescence photon bursts become highly polarized and directional through the back of the film, as compared to traditional weak free-space isotropic emissions. Subsequently, microwave-triggered surface plasmon coupled chemiluminescence (MT-SPCC) appears to be a significant improvement over traditional chemiluminescence “slow glow” for surface assays, as well as other surface plasmon coupled fluorescence based assay technologies, such as surface plasmon coupled emission (SPCE) and surface plasmon coupled fluorescence (SPCF). Mw − Microwave pulses to locally “trigger” chemiluminescence, No Mw − No Microwave pulses, i.e. traditional chemiluminescence “slow glow”.
A Connectomic Atlas of the Human Cerebrum—Chapter 5: The Insula and Opercular Cortex (2018)

In this supplement, we build on work previously published under the Human Connectome Project. Specifically, we show a comprehensive anatomic atlas of the human cerebrum demonstrating all 180 distinct regions comprising the cerebral cortex. The location, functional connectivity, and structural connectivity of these regions are outlined, and where possible a discussion is included of the functional significance of these areas. In part 5, we specifically address regions relevant to the insula and opercular cortex.
Imaging Reactive Oxygen Species in Arthritis (2004)

Reactive oxygen species (ROS) have been shown to play a role in the pathogenesis of arthritides. Luminol was used as the primary reporter of ROS and photons resulting from the chemiluminescence reaction were detected using a super-cooled CCD photon counting system. Luminol was injected intravenously into groups of animals with different models of arthritis. Imaging signal correlated well with the severity of arthritis in focal and pan-arthritis as determined by histological measurement of ROS by formazan. Measurements were highly reproducible, sensitive, and repeatable. In vivo chemiluminescence imaging is expected to become a useful modality to elucidate the role of ROS in the pathogenesis of arthritides and in determining therapeutic efficacy of protective therapies.
Speech LSF quantization with rate independent complexity, bit scalability and learning (2002)

A computationally efficient, high quality, vector quantization scheme based on a parametric probability density function (PDF) is proposed. In this scheme, speech line spectral frequencies (LSF) are modeled as i.i.d realizations of a multivariate Gaussian mixture density. The mixture model parameters are efficiently estimated using the expectation maximization (EM) algorithm. An efficient quantization scheme using transform coding and bit allocation techniques which allows for easy and computationally efficient mapping from observation to quantized value is developed for both fixed rate and variable rate systems. An attractive feature of this method is that source encoding using the resultant codebook involves very few searches and its computational complexity is minimal and independent of the rate of the system. Furthermore, the proposed scheme is bit scalable and can switch between memoryless and quantizer with memory seamlessly. The performance of the memoryless quantizer is 2-3 bits better than conventional quantization schemes.
FE Simulation on Blank Holder Control Using Friction Reducing Algorithm in Deep Drawing Process (2005)

Recent global efforts to resolve environmental issues are required in sheet metal forming. For this reason, some research projects have been focused on unlubricated processes as well as on the use of volatile lubricants. However, low formability due to poor lubrication conditions is still a matter of concern. In this study, in order to improve the friction conditions, a new algorithm for controlling blank holding force (BHF) and punch speed (SPD) was proposed. The concept is to separate the wrinkle eliminating process from drawing process. That is, the process proceeds with an extremely low BHF until a wrinkle sufficiently grows, and the wrinkle is eliminated by BHF loading without punch penetration. Its effectiveness was investigated by finite element (FE) simulation, in which two blank models (0.5mm and 1.0mm thickness) were used. As a result, the maximum forming forces decreased by 5.33%(0.5mm) and 1.55%(1.0mm) compared with those of the uncontrolled model at a constant minimum BHF. In addition, a thinner blank sheet is better for the algorithm on the basis of the result that cup height decreases and thickness distribution increases in the case of 0.5mm thickness.