gebhart/patrepeval huggingface dataset:
862: Comparative Evaluation of Free and Total Forms of Serum Human Glandular Kallikrein 2 and Prostrate Specific Antigen: Which Marker Should we Trust for Prediction of Locally Advanced and Recurrent Prostate Cancer? (2006)

You have accessJournal of UrologyModerated Poster, Monday, May 22, 2006, 1:00 - 3:00 pm1 Apr 2006862: Comparative Evaluation of Free and Total Forms of Serum Human Glandular Kallikrein 2 and Prostrate Specific Antigen: Which Marker Should we Trust for Prediction of Locally Advanced and Recurrent Prostate Cancer? Thomas Steuber, Andrew J. Vickers, Alexander Haese, Ville Vaisanen, K.-H. Felix Chun, Charlotte Becker, Hartwig Huland, James A. Eastham, Peter T. Scardino, and Hans Lilja Thomas SteuberThomas Steuber More articles by this author , Andrew J. VickersAndrew J. Vickers More articles by this author , Alexander HaeseAlexander Haese More articles by this author , Ville VaisanenVille Vaisanen More articles by this author , K.-H. Felix ChunK.-H. Felix Chun More articles by this author , Charlotte BeckerCharlotte Becker More articles by this author , Hartwig HulandHartwig Huland More articles by this author , James A. EasthamJames A. Eastham More articles by this author , Peter T. ScardinoPeter T. Scardino More articles by this author , and Hans LiljaHans Lilja More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)33098-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "862: Comparative Evaluation of Free and Total Forms of Serum Human Glandular Kallikrein 2 and Prostrate Specific Antigen: Which Marker Should we Trust for Prediction of Locally Advanced and Recurrent Prostate Cancer?." The Journal of Urology, 175(4S), p. 278 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 278 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Thomas Steuber More articles by this author Andrew J. Vickers More articles by this author Alexander Haese More articles by this author Ville Vaisanen More articles by this author K.-H. Felix Chun More articles by this author Charlotte Becker More articles by this author Hartwig Huland More articles by this author James A. Eastham More articles by this author Peter T. Scardino More articles by this author Hans Lilja More articles by this author Expand All Advertisement Loading ...
MOCVD Growth of High Quality InGaAs HEMT Layers on Large Scale Si Wafers for Heterogeneous Integration With Si CMOS (2017)

We report on the growth of In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.30</sub> Ga <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.70</sub> As channel high electron mobility transistor (HEMT) epi-layers on a 200-mm Si substrate by metal-organic-chemical-vapor-deposition. The HEMT layers were grown on the Si substrate by using a ~3- <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${\mu }\text{m}$ </tex-math></inline-formula> thick epitaxial buffer composing of a Ge layer, a GaAs layer, and a compositionally graded and strain relaxed InAlAs layer. The optimized epitaxy has a threading dislocation density of less than <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$2 {\times } 10^{{7}}$ </tex-math></inline-formula> cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−2</sup> and a root mean square surface roughness of ~6.7 nm. The device active layers include a <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${ {\delta } }$ </tex-math></inline-formula> -doped InAlAs bottom barrier, a ~15-nm thick InGaAs channel, a ~8-nm InGaP top barrier layer and a heavily doped InGaAs contact layer. MOSHEMTs with channel length down to 130 nm were fabricated. The devices achieve a peak transconductance of <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${\sim }450 ~{\mu }\text{S}/ {\mu }\text{m}$ </tex-math></inline-formula> at <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${V} _{ D}$ </tex-math></inline-formula> of 0.5 V. The peak effective mobility ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${\mu }_{\text {eff}}$ </tex-math></inline-formula> ) in a device with a channel length of 20 <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$ {\mu }\text{m}$ </tex-math></inline-formula> device channel was ~3700 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> / <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\text{V} {\cdot }\text{s}$ </tex-math></inline-formula> .
Development of a wild-type Escherichia coli environmental bloom model to evaluate alternatives to formaldehyde fumigation in broiler chicken hatch cabinets (2020)

Horizontal transmission of opportunistic Escherichia coli during hatch can have detrimental effects on early performance, particularly as pioneer colonizers. Commercially, formaldehyde is often applied in the United States to combat the bacterial bloom that occurs inside of the hatching environment. The purpose of these experiments was to develop a replicable E. coli horizontal challenge model to evaluate alternatives to formaldehyde sanitation applied to the hatching environment. In experiment 1, two trials were conducted for 2 wild-type (WT) E. coli isolates (isolate 1 [I1] or isolate 2 [I2]) to determine the appropriate in ovo challenge dose and day of embryogenesis (DOE) for challenge administration. In experiment 1 trial 1, the most appropriate inoculation dose and time point were determined to be 10<sup>2</sup> cfu/embryo on DOE 19. Experiment 1 trial 2 evaluated whether placement of seeder (direct-challenged) embryos with contact (indirect-challenged) embryos during hatch affected contact hatchability. Trial 2 showed no differences in hatchability between groups. A 7-day experiment (experiment 1 trial 2) was conducted to evaluate the effects of I1 or I2 on horizontal transmission, gram-negative bacterial (GNB) recovery from the gastrointestinal tract (GIT), and impact on BW gain (BWG). Compared with the negative control, seeder, and contact chicks challenged with I1 or I2, we observed increased (P < 0.05) GNB recovered from GIT on the day of hatch. There was a marked (P < 0.05) reduction in 7-day BWG between the I1 indirect-challenged group and the negative control group. To further validate the model, 2 7-day trials (experiment 2, experiment 3) were conducted to evaluate the effects of formaldehyde fumigation on coliform recovery from the hatching environment and on early performance using I1 for the challenge. Isolate 1 positive control hatchers had increased levels of circulating coliforms compared with the negative control and formaldehyde-treated hatchers, although there was no significant impact on performance induced by challenge or formaldehyde treatment in experiment 2 or experiment 3. These data provide a potential model for investigations related to horizontal transmission of WT E. coli at a low dose on DOE 19 to promote simulated commercially relevant bacterial blooms under laboratory conditions.
Renal function and the effects of vericiguat in patients with worsening heart failure with reduced ejection fraction: insights from the VICTORIA ( Vericiguat Global Study in Subjects with HFrEF ) trial (2021)

Renal function trajectories were similar between vericiguat- and placebo-treated patients and the beneficial effects of vericiguat on the primary outcome were consistent across the full range of eGFR and irrespective of WRF.
Epitope Blocking: Positive and Negative Effects on the Biodistribution of 125I‐Labeled Anti‐Tac Disulfide‐stabilized Fv Fragment of Two Antibodies against Different Epitopes of the Circulating Antigen (1998)

Prior in vivo studies using the 125I-labeled anti-Tac disulfide-stabilized variable region fragment (125I-anti-Tac dsFv) of monoclonal antibody in the presence of the circulating soluble alpha subunit of the interleukin-2 receptor (sIL-2R alpha) have shown formation of complexes which interfere with biodistribution. In this study we evaluated the effects of preinjecting HuTac and 7G7/B6, two immunoglobulin Gs (IgGs) that recognize different epitopes of sIL-2R alpha, on the biodistribution of 125I-anti-Tac dsFv in mice bearing SP2/Tac tumor xenografts, which produce sIL-2R alpha, or on nude mice injected with 500 ng of sIL-2R alpha. We also evaluated the biodistribution in mice of 125I-labeled sIL-2R alpha injected alone or with HuTac and 7G7/B6. Injection of either HuTac or 7G7/B6 resulted in complexes with the sIL-2R alpha in serum. Injection of HuTac before 125I-anti-Tac dsFv, in SP2/Tac tumor-bearing mice, resulted in faster clearance of the dsFv from the blood (7.6% ID/g at 30 min), compared to 23.2% ID/g for the no-antibody control; preinjection of 7G7/B6 prolonged the retention of 125I-anti-Tac dsFv to 35.3% ID/g, with more complexes in serum. In mice pre-injected with 7G7/B6 the concentration of 125I-anti-Tac dsFv in tumor was lower (5.2 +/- 0.3% ID/g) than in mice preinjected with HuTac (7.9 +/- 1.2% ID/g) or in the control group (5.6 +/- 0.7% ID/g). In conclusion, while both IgGs formed complexes with sIL-2R alpha and prolonged its retention, preinjection of 7G7/B6 was detrimental, because the increased circulating sIL-2R alpha still had the epitope recognized by the dsFv available for binding and neutralized the anti-Tac dsFv upon injection, whereas preinjection of HuTac blocked the epitope.
Comparison of x-ray diffraction, wafer curvature and Raman spectroscopy to evaluate the stress evolution in Copper TSV's (2012)

In this work we compare techniques to measure the stress in Cu through silicon via's (TSV's) and study the stress as a function of post-plating anneal time and temperature. Our results show that each technique was able to measure the stresses with good agreement. However, wafer curvature was limited to measuring the in-plane stress and the top down Raman spectroscopy geometry is dominated by the out-of-plane stress. Only x-ray diffraction could measure all principal stress components, showing high in-plane stress for longer post-plating anneals that could affect transistor performance.
Stability properties of azimuthally symmetric perturbations in an intense electron beam. Memorandum report (1981)

The Vlasov-Maxwell equations are used to investigate the stability of azimuthally symmetric perturbations (e.g., sausage and hollowing modes) of an electron ion beam immersed in a resistive plasma. The perturbed space charge and plasma current are treated self-consistently for any value of the plasma conductivity. A similar analysis of the hose instability is also carried out. The analysis is carried out for the 'loss-cone' distribution function in which all of the beam electrons have the same value of energy and the same value of axial canonical momentum. In the high conductivity regime, the system is shown to be strongly destabilized by a sufficiently large value of the fractional current neutralization.
Speeding Up SHA-1, SHA-256 and SHA-512 on the 2nd Generation Intel&#x0AE; Core&#153; Processors (2012)

This paper discusses some software techniques, targeted specifically to the 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">nd</sup> Generation Intel <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> Core™ processor, for speeding up the NIST standardized Secure Hash Algorithms SHA-1, SHA-256 and SHA-512. We demonstrate the advantage of our optimizations by applying them to a few publicly available code examples, obtaining SHA-1, SHA-256 and SHA-512 at, respectively, 5.75, 15.31, 9.71 cycles per byte.
Hb O Indonesia (α2116(Gh4) Glu → Lys β2): in Association with β-Thalassemia (1978)

(1978). Hb O Indonesia (α2 116(Gh4) Glu → Lys β2): in Association with β-Thalassemia. Hemoglobin: Vol. 2, No. 1, pp. 59-63.
SpectralNET – an application for spectral graph analysis and visualization (2005)

SpectralNET provides an easily accessible means of analyzing graph-theoretic metrics for data modeling and dimensionality reduction. SpectralNET is publicly available as both a .NET application and an ASP.NET web application from http://chembank.broad.harvard.edu/resources/. Source code is available upon request.
Cyclopropane-Containing Polyamine Analogues Are Efficient Growth Inhibitors of a Human Prostate Tumor Xenograft in Nude Mice (2003)

Polyamine analogues 7, 10, 18, 27, and 32 containing cyclopropane rings were obtained by chemical synthesis. Their antineoplastic activities were assessed against the cultured human prostate tumor cell lines DU-145, DuPro, and PC-3. Decamines 32 and 27 exhibited variable levels of cytotoxicity against all three cell lines, while 7, 10, and 18 were efficacious against DU-145 and DuPro. Maximum tolerated doses (MTD) for all five compounds in a NCr-nu mouse model were determined at dosing schedules of q1d x 5 (ip) in two cycles with a break of 10 days between cycles. Their antitumor efficacies were then tested against DU-145 tumor xenografts in mice treated with all five agents at their respective MTDs. In addition, the efficacies of 7 and 10 against the same tumor xenograft were assessed at doses below their respective MTDs. In all experiments, administration began two weeks after tumor implantation. All compounds efficiently inhibited tumor growth for up to 50 days postimplantation, with negligible animal body weight loss. Tetramine 10 and hexamine 18 were the most efficient among the five analogues in arresting tumor growth. Tetramine 10 containing two cyclopropane rings had the lowest systemic toxicity as reflected in animal body weight loss. It was further assessed at a weekly administration regimen of (q1w x 4) in two cycles with a four-week break between the cycles. At this dosing schedule, 10 again efficiently arrested tumor growth with negligible effect on animal body weight. Tetramine 10 also arrested the growth of large tumors (ca. 2000 mm(3)) treated 66 days postimplantation. Studies on the metabolism of 10 showed that it accumulates in tumor within 6 h after the end of administration and reached a maximum level 72 h after cessation of dosing. Intracellular concentrations of 10 in liver and kidney were much smaller when compared to those in the tumor when measured 72 h after cessation of dosing. In liver and kidney, the deethyl metabolites of 10 accumulated over a 96 h period after cessation of dosing.
ChemInform Abstract: Potent Bicyclic Lactam Inhibitors of Thrombin. Part 1. P3 Modifications. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Utilization of two microphones for real-time low-latency audio smartphone apps (2018)

This paper presents an approach to overcome the limitation imposed by existing smartphone operating systems in using two microphones of smartphones at the same time for real-time low-latency audio apps that require the use of two microphones. This approach involves the use of an external dual-microphone and the processing steps needed to access audio signals from both of the external microphones at the same time. The developed approach is then applied to two example audio applications consisting of noise classification and noise reduction. It is shown that these dual-microphone apps lead to improved noise classification and noise reduction accuracy compared to the apps using a single microphone.
High-Efficiency Nitride-Base Photonic Crystal Light Sources (2010)

The research activities performed in the framework of this project represent a major breakthrough in the demonstration of Photonic Crystals (PhC) as a competitive technology for LEDs with high light extraction efficiency. The goals of the project were to explore the viable approaches to manufacturability of PhC LEDS through proven standard industrial processes, establish the limits of light extraction by various concepts of PhC LEDs, and determine the possible advantages of PhC LEDs over current and forthcoming LED extraction concepts. We have developed three very different geometries for PhC light extraction in LEDs. In addition, we have demonstrated reliable methods for their in-depth analysis allowing the extraction of important parameters such as light extraction efficiency, modal extraction length, directionality, internal and external quantum efficiency. The information gained allows better understanding of the physical processes and the effect of the design parameters on the light directionality and extraction efficiency. As a result, we produced LEDs with controllable emission directionality and a state of the art extraction efficiency that goes up to 94%. Those devices are based on embedded air-gap PhC - a novel technology concept developed in the framework of this project. They rely on a simple and planar fabrication process that is very interesting for industrial implementation due to its robustness and scalability. In fact, besides the additional patterning and regrowth steps, the process is identical as that for standard industrially used p-side-up LEDs. The final devices exhibit the same good electrical characteristics and high process yield as a series of test standard LEDs obtained in comparable conditions. Finally, the technology of embedded air-gap patterns (PhC) has significant potential in other related fields such as: increasing the optical mode interaction with the active region in semiconductor lasers; increasing the coupling of the incident light into the active region of solar cells; increasing the efficiency of the phosphorous light conversion in white light LEDs etc. In addition to the technology of embedded PhC LEDs, we demonstrate a technique for improvement of the light extraction and emission directionality for existing flip-chip microcavity (thin) LEDs by introducing PhC grating into the top n-contact. Although, the performances of these devices in terms of increase of the extraction efficiency are not significantly superior compared to those obtained by other techniques like surface roughening, the use of PhC offers some significant advantages such as improved and controllable emission directionality and a process that is directly applicable to any material system. The PhC microcavity LEDs have also potential for industrial implementation as the fabrication process has only minor differences to that already used for flip-chip thin LEDs. Finally, we have demonstrated that achieving good electrical properties and high fabrication yield for these devices is straightforward.
Causes of Proliferative Retinopathy Following Pneumatic Retinopexy-Reply (1990)

<h3>In Reply.</h3> —Pneumatic retinopexy has several potential advantages for the management of some retinal detachments.<sup>1,2</sup>It involves much less manipulation than a scleral buckle and does not require a conjunctival incision; it therefore (1) eliminates the need to go to the operating room, (2) speeds rehabilitation and visual recovery, (3) decreases the likelihood of muscle imbalance, (4) eliminates surgically induced refractive error, and (5) eliminates conjunctival and episcleral scarring that can complicate future surgical procedures. Initially it was used for a select group of detachments with superior breaks not more than 1 clock hour apart, but enthusiasm generated by the above advantages has prompted some surgeons to expand their indications. As experience with the techique has grown, so has the list of potential disadvantages, which now includes (1) the development of new retinal breaks, (2) the development of folds through the macula, (3) detachment of a previously attached macula,
Magnetization switching in ferromagnets by adsorbed chiral molecules without current or external magnetic field (2017)

Ferromagnets are commonly magnetized by either external magnetic fields or spin polarized currents. The manipulation of magnetization by spin-current occurs through the spin-transfer-torque effect, which is applied, for example, in modern magnetoresistive random access memory. However, the current density required for the spin-transfer torque is of the order of 1 × 10<sup>6</sup> A·cm<sup>-2</sup>, or about 1 × 10<sup>25</sup> electrons s<sup>-1</sup> cm<sup>-2</sup>. This relatively high current density significantly affects the devices' structure and performance. Here we demonstrate magnetization switching of ferromagnetic thin layers that is induced solely by adsorption of chiral molecules. In this case, about 10<sup>13</sup> electrons per cm<sup>2</sup> are sufficient to induce magnetization reversal. The direction of the magnetization depends on the handedness of the adsorbed chiral molecules. Local magnetization switching is achieved by adsorbing a chiral self-assembled molecular monolayer on a gold-coated ferromagnetic layer with perpendicular magnetic anisotropy. These results present a simple low-power magnetization mechanism when operating at ambient conditions.