gebhart/patrepeval huggingface dataset:
Charging of Polymeric Surfaces by Positive Impulse Corona (2009)

This paper focuses on analysis of charging of polymeric surfaces by means of impulse corona discharges in air. Internal (space charge densities and electric fields) as well as external (circuit current) characteristics of corona in a point-plane electrode configuration are investigated by means of computer simulations. Two types of onset positive corona modes, namely positive glow corona and burst pulse corona are identified. The developed and verified computer model is further used to study corona charging of a 2 mm thick polymeric material sample. Both the mechanism of charge deposition and distribution of deposited charges on the surface are dependent on the mode of the corona discharge used. In the case of glow corona, charge generation is limited to the anode region and the generated charges move towards the sample surface under applied electric field. Thereafter the deposited charge cloud expands radially along a portion of the surface with fairly constant concentration. In the case of burst pulse corona, series of positive charge clouds start from the anode and move towards the sample surface in a wave-like manner. Each burst contributes to the deposited charge, which spreads over the surface less extensively than that observed during glow corona charging.
Decreased facial expression variability in patients with serious cardiopulmonary disease in the emergency care setting (2014)

With a single visual stimulus, patients with serious cardiopulmonary diseases lacked facial expression variability and surprise affect. Our preliminary findings suggest that stimulus-evoked facial expressions from emergency department patients with cardiopulmonary symptoms might be a useful component of gestalt pretest probability assessment.
Abstract 830: MiRNA-106a and LITAF are novel modulators of prostate cancer radioresistance (2017)

Abstract Prostate cancer (PCa) is the second most prevalent cancer affecting men worldwide, with radiotherapy being a primary treatment modality. PCa recurrence is a major clinical problem with up to a 40% biochemical recurrence rate at five years after external beam radiotherapy (ionizing radiation, IR). Therefore, there is an unmet need to characterize radioresistance in order to improve therapy and patient outcomes. MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression. MiRNAs are aberrantly expressed in cancer, specifically, miR-106a has been found to be overexpressed in various cancer types. The purpose of this study is to determine whether miR-106a confers IR resistance and tumor aggression in PCa. Utilizing The Cancer Genome Atlas Data Portal, bioinformatics analysis discovered that miR-106a was significantly overexpressed in PCa samples relative to normal prostate. This suggests that miR-106a is involved in prostate carcinogenesis. Clonogenic survival assays revealed that cells overexpressing miR-106a had increased survival after IR treatment compared to control cells. Proliferation assays showed that miR-106a cells had a higher proliferation rate than control cells in both unirradiated and IR-treated cells. Affymetrix gene array analysis was used to identify possible targets of miR-106a. Combining results from the gene array, in silico prediction algorithms, and in vitro analyses, we identified lipopolysaccharide-induced TNFα factor (LITAF) as a target of miR-106a. In addition, LITAF knockdown lead to increased proliferation and clonogenic survival following IR, recapitulating the phenotype of miR-106a overexpression. Cells were stained for β-galactosidase expression following IR to assess senescence, as a mode of cell death. We found that both miR-106a overexpression and LITAF knockdown resulted in significantly fewer senescent cells post-IR. Upon examination of critical DNA damage response genes, we found that miR-106a overexpression and LITAF knockdown increased expression of ATM mRNA and protein. Upregulation of ATM is associated with IR resistance, elucidating the mechanism by which miR-106a overexpression and LITAF knockdown are involved in radioresistance. Tumor xenograft experiments, using a PCa cell line stably overexpressing miR-106a, confirmed that miR-106a increases proliferation compared to control tumors before and after IR. Thus, our results strongly suggest that miR-106a is involved in PCa aggression and confers a radiation-resistant phenotype, by targeting the novel radiation response gene LITAF. Note: This abstract was not presented at the meeting. Citation Format: Christianne Hoey, Jessica Ray, Paul Boutros, Stanley K. Liu. MiRNA-106a and LITAF are novel modulators of prostate cancer radioresistance [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 830. doi:10.1158/1538-7445.AM2017-830
Delivering HIV treatment & care in resource limited settings - Therapeutic mobile units (2012)

A weak state health infrastructure and a disparate system of rural clinics render the delivering of treatment and care of HIV/AIDS patients in sub-Saharan Africa extremely difficult. Furthermore, because patients living in remote areas do not have access to lab facilities, we developed a decentralized strategy based on bringing the needed services closer to the people, through the use of Therapeutic Mobile Units (TMU) as potentially useful means to follow up adults and children undergoing antiretroviral treatment. Using the TMU of the National Public Health Laboratory of the Cameroon Ministry of Health, we conducted several cross-sectional surveys on epidemiological, biological and clinical features of HIV/AIDS in young and elderly patients in Cameroon. The screening of HIV-specific antibodies was carried out using rapid tests. Indeterminate or positive samples were immediately retested. People diagnosed as HIV-infected were provided free biological monitoring and referred to health care centres. The TMU was also equipped with the Auto40 cytometer for CD4 determination. A FACSCalibur cytometer was used as reference method. From April 2005 to July 2011, 120 campaigns were organised in Cameroon (average of 277 volunteers tested per day). Out of 32, 970 volunteers who received a pre-test counselling, 32, 869 (20,937 males; 11,932 females) tested for HIV (acceptance rate of 99.69%). Their average age was 31 years. Amongst those, 32,569 (99.08%) received post-test counselling. The overall HIV prevalence was 6.06% [with higher rates in women, data not shown]. CD4 testing was performed using the Auto40 cytometer and gave a perfect correlation with the reference method (FASCSCalibur) [mean±SD CD4 T cell count was 1041±317 cells/ml by Auto40, and 1032±294 cells/ml by FACSCalibur; r2=0.982]. For patients receiving ART, our medical staff provided support in monitoring treatment, recording information about patient's medical status, resolving the barriers to drug adherence and others factors that may affect a patient ART therapy (data not shown). With nearly eighty percent of patients not receiving appropriate care in Sub Saharan Africa, TMU likely constitutes a useful tool in providing large scale up HIV testing, biological monitoring, treatment and care and should be integrated into national HIV control programmes.
Species, dose and energy dependence of implant induced transient enhanced diffusion (2002)

Special test structures which separate implant damage from a buried monitor boron layer were used to observe the transient diffusion associated with implant annealing. The large anomalous diffusion length is independent of implant species but strongly dependent on implant energy. This is modeled by enhanced Frenkel pair recombination along dense cascade damage tracks associated with heavier ions. The enhancement in the buried layer diffusion also depends on the concentration of the buried layer, even below the intrinsic electron concentration. We propose that boron clusters formed by high populations of mobile boron are necessary in order to model transient diffusion effects.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Near-infrared spectroscopy and MRI co-registration of tumor tissue physiology (2002)

We studied the physiological changes in animal model tumors by co-registration of near-infrared spectroscopy and MRI. T2 weighted and Gd-DTPA enhanced MRI images correlate with changes observed in Hb, HbO2 and water concentrations measured by near-infrared spectroscopy.
Greater Dose-Ranging Effects on A1C Levels Than on Glucosuria With LX4211, a Dual Inhibitor of SGLT1 and SGLT2, in Patients With Type 2 Diabetes on Metformin Monotherapy (2014)

Dual inhibition of SGLT1/SGLT2 with LX4211 produced significant dose-ranging improvements in glucose control without dose-increasing glucosuria and was associated with reductions in weight and systolic BP in metformin-treated patients with type 2 diabetes.
Resonance Raman Characterization of Tetracene Monomer and Nanocrystals: Excited State Lattice Distortions With Implications For Efficient Singlet Fission (2019)

The characterization of specific phonon modes and exciton states that lead to efficient singlet fission (SF) may be instrumental in the design of the next generation of high-efficiency photovoltaic devices. To this end, we analyze the absolute resonance Raman (RR) cross sections for tetracene (Tc) both as a monomer in solution and as a crystalline solid in an aqueous suspension of nanocrystals. For both systems, a time-dependent wavepacket model is developed that is consistent with the absolute RR cross sections, the magnitude of the absorption cross sections, and the vibronic line shapes of the fluorescence. In the monomer, the intramolecular reorganization energy is between 1500 and 1800 cm<sup>-1</sup> and the solvent reorganization energy is 70 cm<sup>-1</sup>. In nanocrystals, the total reorganization is diminished to less than 600 cm<sup>-1</sup>. The lowest energy exciton has an estimated intramolecular reorganization energy between 300 and 500 cm<sup>-1</sup> while intermolecular librational phonons have a reorganization energy of about 130 cm<sup>-1</sup>. The diminished reorganization energy of the nanocrystal is interpreted in the context of the delocalization of the band-edge exciton onto about ∼7 molecules. When electron and electron-hole correlations are included within many-body perturbation theory, the polarized absorption spectra of crystalline Tc are calculated and found to be in agreement with experiment. The low-lying exciton states and optically active phonons that contribute to the polarized crystal absorption are identified. The likely role of coherent exciton phonon evolution in the SF process is discussed.
ATRP of methyl methacrylate using a novel binol ester-based bifunctional initiator (2004)

Novel bifunctional initiators [1,1′-Bi-2-naphthol bis(2-bromo-2-methylpropionate); (R)-, (S)-, and racemic-] were synthesized from the esterification of 1,1′-bi-2-naphthol and used as initiators in atom transfer radical polymerization (ATRP) in conjunction with N,N,N′,N′,N″-pentamethyldiethylenetriamine (PMDETA), and copper (I) bromide or copper (I) chloride. The initiators synthesized were completely characterized by UV, FTIR, NMR, and Mass spectroscopies. A detailed investigation of the ATRP of methyl methacrylate (MMA) with the bifunctional initiators (BBiBN) along with CuBr or CuCl/PMDETA catalyst system in anisole was carried out at 30 °C. Thus, MMA polymerization is shown to proceed with first-order kinetics, with predicted molecular weight, and narrow polydispersity indices. The ATRP of glycidyl methacrylate (GMA) and tert-butyl acrylate (tBA) were also performed with BBiBN initiator in conjunction with CuBr/PMDETA catalyst system. The polymerization of GMA was carried out at 30 °C, but tBA was polymerized at 60 °C. Gel permeation chromatography (GPC), FTIR, NMR, UV spectroscopies, and TGA were used for the characterization of the polymers synthesized. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 42: 902–915, 2004
Compositional characteristics of the essential oil ofMyrtus communisgrown in the central part of Saudi Arabia (2013)

The essential oil obtained from aerial parts of Myrtus communis grown in the central part of Saudi Arabia was analyzed by gas chromatography-based techniques (GC–FID, GC–MS, Co–GC, LRI determination, database, and literature search) using polar as well as non-polar columns, which resulted in the identification of a total of sixty-five components accounting for 98.2% of the total oil composition. The oil composition was found to be dominated by monoterpene components accounting for 89.3% of oil composition. Sesquiterpenes (4.8%) and their oxygenated derivatives (3.5%) were present in lesser amounts. The major compounds of the oil were 1,8-cineole (26.5%), linalool (18.0%), α-pinene (11.6%), α-terpineol (8.9%), and limonene (4.0%). Other constituents which were present in appreciable amounts in this oil are trans-geraniol (3.9%), trans-geranyl acetate (3.9%), α-terpenyl acetate (3.3%), linalyl acetate (2.9%), and δ-cadinene (2.7%).
Temporal distribution of brain/plasma ratio of <sup>3</sup>H-D3 after different administration routes. (2015)

&lt;p&gt;Following bolus dose administration, low brain/plasma ratios were found at the starting time points. After 4 hours, the ratios reached relative high values and varied between 0.7–1.0. Upon i.p. pump implantation the ratio increased constantly with time.&lt;/p&gt;
A 32-channel multi-coil shim setup optimized for the human brain, pushing the limits of shimming at 9.4T (2019)

Multi-coil shimming is an effective approach to reduce B0 field inhomogeneity. In this work, we optimized a 32-channel multi-coil to fit best for shimming of the human brain. The individual coils are optimized in terms of size and position. The performance is compared with the conventional symmetric design.
Interspecies cross‐talk between co‐cultured Pseudomonas putida and Escherichia coli (2017)

Pseudomonas putida and Escherichia coli are ubiquitous microorganisms that can be isolated from soil rhizosphere, the surface of vegetables, fresh waters and wastewaters - environments in which they likely co-exist. Despite this, the potential interactions between these microbes have not been studied in detail. To analyse these interactions, we carried out RNA-seq transcriptomic analysis of these microbes as monocultures and as co-cultures. Our results show that co-culture of these microbes significantly alters transcriptional profiles. The most dramatic transcriptional changes in both microorganisms were involved in central carbon metabolism, as well as adhesion to surfaces and the activation of drug efflux pumps. We also found that acetate production was one of the mechanisms used by E. coli K-12 MG1655 in response to the presence of P. putida DOT-T1E.
Synthesis of 4-Aryl and Unsymmetrical 4,6-Diarylpyrimidines by the Suzuki-Miyaura Cross-Coupling Reaction (2018)

Melting points were obtained on a Electrothermal IA9100 Melting Point Apparatus and are uncorrected. 1H and 13 C spectra were recorded on Bruker Avance-400 MHz spectrometer.The chemical shifts of 1 H and 13 C NMR signals are quoted relative to internal CHCl3 (δ = 7.26) and CDCl3 (δ =77.0) or tetramethylsilane (δ = 0.0).Multiplicities are reported as follows: singlet (s), doublet (d), doublet of doublets (dd), doublet of triplets (dt), triplet (t), quartet (q), multiplet (m) and broad singlet (brs).The GC-MS analyses were performed on an Agilent 6890 GC coupled with an Agilent 5973 inert MS under EI conditions.High resolution mass spectra were obtained on a GCT Mass Spectrometer (Waters, Micromass) and a QSTAR XL hybrid mass Spectrometer (Applied Biosystems/MDS Sciex).IR spectra were recorded on a Bruker Alpha FT-IR spectrometer.Column chromatography was performed using silica gel (230-400 mesh) as the stationary phase.All reactions were monitored by thin layer chromatography (TLC).All reagents and solvents were purchased from commercial sources and used without purification.N-Benzyl-6-chloropyrimidin-4-amine was prepared by a reported procedure.
Device-to-device collaboration through distributed storage (2012)

Video is the main driver for the inexorable increase in wireless data traffic. In this paper we analyze a new architecture in which device-to-device (D2D) communications is used to drastically increase the capacity of cellular networks for video transmission. Users cache popular video files and - after receiving requests from other users - serve these requests via D2D localized transmissions; the short range of the D2D transmission enables frequency reuse within the cell. We analyze the scaling behavior of the throughput with the number of devices per cell. The user content request statistics, as well as the caching distribution, are modeled by a Zipf distribution with parameters γ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r</sub> and γ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</sub> , respectively. For the practically important case γ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r</sub> <; 1 and γ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> > 1, we derive a closed form expression for the scaling behavior of the number of D2D links that coexist without interference. Our analysis relies on a novel Poisson approximation result for wireless networks obtained through the Chen-Stein Method.
Synthesis, Characterization, and Application of Tunable Resistance Coatings Prepared By Atomic Layer Deposition (2013)

Abstract not Available.
Acute and Impaired Wound Healing (2012)

This is the first installment of 2 articles that discuss the biology and pathophysiology of wound healing, review the role that growth factors play in this process, and describe current ways of growth factor delivery into the wound bed. Part 1 discusses the latest advances in clinicians' understanding of the control points that regulate wound healing. Importantly, biological similarities and differences between acute and chronic wounds are considered, including the signaling pathways that initiate cellular and tissue responses after injury, which may be impeded during chronic wound healing.
On the Use of the Smith-McMillan Form in Decoupling System Dynamics (2021)

In this paper, the use of the Smith-McMillan form in decoupling multiple-input multiple-output system dynamics is analyzed.In short, from a transfer matrix plant model one can obtain a decoupling compensator which leads to a decoupled plant that contains the same transmission poles and zeros of the transfer matrix of the original system.As a result, full decoupling of the plant transfer matrix is obtained for all frequencies, which can be individually addressed by single-input single-output control.The aim of this paper is to present conditions for the decoupled system that guarantee internal stability and performance requirements for the overall control system.Performance specifications are defined in terms of magnitude limits for the maximum singular value of the closed-loop transfer matrices.The potential of the decoupling procedure is shown in a simulation study of a mechanical system.
Investigación e impacto ambiental de los edificios. La energía (2005)

Se presenta la problemática actual del uso de la energía de cara al agotamiento de las fuentes fósiles, el abastecimiento y la contaminación atmosférica de gases tóxicos, de efecto invernadero y destructores de la capa de ozono. Se comenta la relevancia de la energía en el impacto ambiental de los edificios y se discuten los distintos aspectos que inciden en la posible evolución futura del problema y en la mejor estrategia de investigación tecnológica para tratar de mejorar la eficiencia energética y medioambiental de los edificios, especialmente en España. Se presentan las tecnologías actuales de introducción de las energías renovables en los edificios y se comentan sus más relevantes características, haciendo hincapié en las barreras para su difusión. Se describe la actividad más reciente de investigación en la climatización por energía solar haciendo uso de máquina de absorción, con aplicación a Madrid.
<title>Multiscale stochastic approach to object detection</title> (1993)

We present a method for object detection based on a novel multiscale stochastic model together with Bayesian estimation techniques. This approach results in a fast, general algorithm which may be easily trained for specific objects. The object model is based on a stochastic tree structure in which each node is an important subassembly of the three dimensional object. Each node or subassembly is modeled using a Gaussian pyramid decomposition. The objective of the algorithm is then to estimate the unknown position of each subassembly, and to determine on the presence of the object. We use a fast multiscale search technique to compute the sequential MAP (SMAP) estimate of the unknown position, scale factor, and 2-D rotation for each subassembly. The search is carried out in a manner similar to a sequential likelihood ratio test, where the process advances in scale rather than time. We use a similar search to estimate the model parameters for a given object from a set of training images.
Mobile Services for Enhancing Human Crowdsourcing with Computing Elements (2014)

Crowdsourcing enables one to leverage the power of the crowd. Normally, it involves utilizing humans for tasks that machines have difficulty performing. We propose a system, delivered as a mobile service, which dynamically adapts to the application domain and selects a combination of human and machine crowdsourcing components. Our work is towards the design of elastic systems that adaptively optimizes the use of human and automated software resources in order to maximize overall performance. We propose a performance model that predicts both human and machine outcomes for a certain task and then optimizes task assignment accordingly. Our experimentation shows that our proposed system significantly enhances the outcome precision of a crowdsourced task.
Feasibility of integrative games and novel therapeutic game controller for telerehabilitation of individuals chronic post-stroke living in the community (2019)

These findings indicate the feasibility and efficacy of the system in providing home-based telerehabilitation. The BrightBrainer system needs to be further evaluated in randomized control trials and with individuals early post-stroke.
Recombinant tumour necrosis factor inhibits malaria parasites in vivo but not in vitro. (1987)

As tumour necrosis serum kills malarial parasites in vitro and inhibits the multiplication of some species of Plasmodium in mice, we examined the effect of recombinant mouse tumour necrosis factor (rTNF) on P. yoelii both in vitro and in vivo. Parasites incubated overnight with rTNF showed no loss of viability, but repeated injection of rTNF into infected mice reduced parasitaemia and significantly prolonged survival of mice infected with a lethal variant of the parasite. We conclude that TNF acts on blood-stage malaria in vivo via a host cell and that another molecule in tumour necrosis serum is involved in killing the parasite in vitro.