gebhart/patrepeval huggingface dataset:
MIDDLE-R (2005)

The widespread use of clusters and Web farms has increased the importance of data replication. In this article, we show how to implement consistent and scalable data replication at the middleware level. We do this by combining transactional concurrency control with group communication primitives. The article presents different replication protocols, argues their correctness, describes their implementation as part of a generic middleware, Middle-R, and proves their feasibility with an extensive performance evaluation. The solution proposed is well suited for a variety of applications including Web farms and distributed object platforms.
Breathing abnormalities insleep in achondroplasia (2011)

Overnight sleepstudies were performed in 20 subjects withachondroplasia to documentfurther therespiratory abnormalities presentinthisgroup. Somatosensory evokedpotentials (SEPs)were recorded in19ofthesubjects toscreenfor thepresenceofbrainstem abnormalities, whichare one ofthepotential aetiological mechanisms. Fifteen children aged1 to 14 years, and fiveyoung adults, aged 20 to 31 years were included. Allhad upper airwayobstruction and15(75%) hada pathological apnoea index(greater thanfive per hour).Othersleepassociatedrespiratory abnormalities, including partial obstruction, central apnoea, and abnormalelectromyographic activity of accessory musclesofrespiration, also showeda highprevalence. SEPs were abnormalineight(420/%), butthere was no correlation betweenabnormalSEPsand apnoea duringsleep, either qualitatively or quantitatively. A highprevalence of bothsleeprelatedrespiratory abnormalities and abnormalSEPs inyoung subjects withachondroplasia was demonstrated. However,thesleeprelated respiratory abnolrmalities do not always result insignificant bloodgas disturbances or correlate withabnormalSEPsin this group. (Arch DisChild 1993; 69:191-196)
Enhancement of respiratory syncytial virus-induced cytopathology by trypsin, thrombin, and plasmin (1983)

A series of proteases of diverse substrate specificity were tested for their effect on respiratory syncytial virus-induced cytopathology. Three of the enzymes, thrombin, plasmin, and trypsin, were able to augment significantly the fusion of virus-infected A549 cells. On a concentration basis, thrombin was the most active promoter, followed by plasmin and then trypsin. Hirudin, a specific thrombin inhibitor, blocked the fusion-enhancing property of thrombin, yet had no influence on the basal rate of fusion in the absence of the enzyme. By contrast, the amidine-type inhibitors of trypsin-like proteases, bis(5-amidino-2-benzimidazolyl)-methane (BABIM), blocked not only the thrombin effect, but also the fusion in the thrombin-free controls. The suppressive activity of BABIM was observed at concentrations so low as to exclude any direct inhibitory effect on thrombin itself. These results make it seem very likely that thrombin advances cell fusion by activating a BABIM-sensitive protease. Plasmin and trypsin can be expected to act in a similar manner.
A framework for human microbiome research (2012)

A variety of microbial communities and their genes (the microbiome) exist throughout the human body, with fundamental roles in human health and disease. The National Institutes of Health (NIH)-funded Human Microbiome Project Consortium has established a population-scale framework to develop metagenomic protocols, resulting in a broad range of quality-controlled resources and data including standardized methods for creating, processing and interpreting distinct types of high-throughput metagenomic data available to the scientific community. Here we present resources from a population of 242 healthy adults sampled at 15 or 18 body sites up to three times, which have generated 5,177 microbial taxonomic profiles from 16S ribosomal RNA genes and over 3.5 terabases of metagenomic sequence so far. In parallel, approximately 800 reference strains isolated from the human body have been sequenced. Collectively, these data represent the largest resource describing the abundance and variety of the human microbiome, while providing a framework for current and future studies.
The Dancers Hip: Extreme ROM Impingement / Instability: Anatomy & Arthroscopic Clinical Outcomes (2015)

Management of hip pain in Dancers can be very challenging secondary to the complex demands placed on their hips. Between 2009 and 2014, hip arthroscopy was performed for 51 hips with a mean age 21.0 years in competitive dancers. Specific types of dance performed included 36 studio dance and 32 high kick dance. Morphology included Cam-type FAI (78%), Pincer-type FAI (50%), Subspine impingement (82%), Borderline dysplasia (20%), Dysplasia (4%), and Normal (2%). The mean preoperative LCE angle was 29.9 deg, alpha angle was 52.3 deg (Lateral), and offset ratio was 0.16. A positive Cross-over (COS) and Posterior Wall (PW) sign were present in 60% of hips, and the mean Tonnis angle was 3.2 deg. Outcomes were evaluated with MHHS, SF-12 scores, VAS scores. At mean 16.0 months follow-up, the mean outcome improvements were 24.8 points (MHHS), 12.2 points (SF-12), 4.1 points (VAS), (p0.05). The lateral alpha angle improved from a 52.3 deg to 37.9 deg, and femoral offset ratio improved from .16 to .20 (all p Hip pain in dancers can be challenging secondary to extreme hip ROM driven impingement / instability with resultant high demands placed on the hips. An arthroscopic approach addressing hip joint pathology including subtle morphologic and physiologic cam and pincer impingement and highly prevalent subspine impingement and capsular laxity led to significantly improved outcomes for competitive dancers.
Homo- and Copolymerization of Strained Cyclic Olefins with New Palladium(II) Complexes Bearing Ethylene-Bridged Heterodonor Ligands (2001)

Amorphous and high molar mass polymers of norbornene and phenylnorbornene (endo/exo ratio of 80/20) were prepared by the use of new dicationic palladium(II) single-component catalysts of the general type [Pd(L∩L)(NCCH3)2](BF4)2. [(L∩L) = 2-(diphenylarsino)-1-(methylthio)ethane (S∩As, 1) (4), 2-(diphenylphosphino)-1-methylthio)ethane (S∩P, 2) (5), 1, 2-bis(diphenylphosphino)ethane (P∩P, 3) (6). With increasing the trans influence of the donor atom in the ligands (P > As > S) the polymerization activity of the catalysts towards polymerization of norbornene increases instantly. Both the molecular weight and the thermal behavior of the polymer can be tailored using ethene as chain transfer agent. Catalyst 4 is also active towards the alternating copolymerization of carbon monoxide and norbornene. The isolated copolymer is highly soluble in toluene, THF and chlorinated solvents. The DSC measurement of the norbornene-carbon monoxide copolymer showed a melting temperature (Tm) of 241°C (ΔHf = 47.3 J/g) and a glass transition temperature (Tg) of 161°C which is about 170°C lower compared to the homopolynorbornene (Tg ≅ 330°C).
SDRAM-Energy-Aware Memory Allocation for Dynamic Multi-Media Applications on Multi-Processor Platforms (2005)

Heterogeneous multi-processors platforms are an interesting option to satisfy the computational performance of future multi-media applications. Energy-aware data management is crucial to obtain reasonably low energy consumption on the platform. In this paper we show that the assignment of data of dynamically created/deleted tasks to the shared main memory has a large impact on platform’s energy consumption. We introduce two dynamic memory allocators, which optimize the data assignment in the context of shared multi-banked memories.
Reporting Device Performance of Emerging Photovoltaic Materials (Version 1) (2021)

Emerging photovoltaics (PVs), focuses on a variety of applications complementing large scale electricity generation. For instance, organic, dye-sensitized and some perovskite solar cells are considered in building integration, greenhouses, wearable and indoors, thereby motivating research on flexible, transparent, semitransparent, and multi-junction PVs. Nevertheless, it can be very time consuming to find or develop an up-to-date overview over the state-of-the-art performance for these systems and applications. Two important resources for record research cells efficiencies are the National Renewable Energy Laboratory chart and the efficiency tables compiled biannually by Martin Green and colleagues. Both publications provide an effective coverage over the established technologies, bridging research and industry. An alternative approach is proposed here summarizing the best reports in the diverse research subjects for emerging PVs. Best performance parameters are provided as a function of the photovoltaic bandgap energy for each technology and application, and are put into perspective using, e.g., the Shockley-Queisser limit. In all cases, the reported data correspond to published and/or properly described certified results, with enough details provided for prospective data reproduction. Additionally, the stability test energy yield (STEY) is included as an analysis parameter among state-of-the-art emerging PVs.
Treatment of upper gastrointestinal bleeding in 2020: New techniques and outcomes (2020)

The clinical outcome of upper gastrointestinal bleeding has improved due to advances in endoscopic therapy and standardized peri-endoscopy care. Apart from validating clinical scores, artificial intelligence-assisted machine learning models may play an important role in risk stratification. While standard endoscopic treatments remain irreplaceable, novel endoscopic modalities have changed the landscape of management. Over-the-scope clips have high success rates as rescue or even first-line treatments in difficult-to-treat cases. Hemostatic powder is safe and easy to use, which can be useful as temporary control with its high immediate hemostatic ability. After endoscopic hemostasis, Doppler endoscopic probe can offer an objective measure to guide the treatment endpoint. In refractory bleeding, angiographic embolization should be considered before salvage surgery. In variceal hemorrhage, banding ligation and glue injection are first-line treatment options. Endoscopic ultrasound-guided therapy is gaining popularity due to its capability of precise localization for treatment targets. A self-expandable metal stent may be considered as an alternative option to balloon tamponade in refractory bleeding. Transjugular intrahepatic portosystemic shunting should be reserved as salvage therapy. In this article, we aim to provide an evidence-based comprehensive review of the major advancements in endoscopic hemostatic techniques and clinical outcomes.
Heat Exchangers and Cold Plates (2002)

A heat exchanger is a device that is used to transfer thermal energy from one fluid to another. The process involves two fluids. On the other hand, a cold plate involves only one fluid that is used to cool (or heat) a system. The general analysis and design principles for a cold plate are identical to those for a heat exchanger. Therefore, all discussion in this chapter will be confined to heat exchangers. Heat exchangers are normally used to cool the circulating fluid in electronic equipment.
Synthesis of (−)-Morphine (2002)

The preparation of the diastereomerically pure beta-tetralone ketal 4 is reported. Intramolecular alkylidene C-H insertion followed by hydrolysis of 4 proceeded to give the enantiomerically pure cyclopentene 15. The key step in this synthesis was the bis-intramolecular cyclization of keto aldehyde 2 to give the tetracyclic intermediate 20. Enone 20 was converted over several steps to (-)-morphine 1.
Vanadium Phosphate Oxide Seeds and Their Influence on the Formation of Vanadium Phosphate Catalyst Precursors (2010)

Abstract Vanadium phosphate materials, based on a VOHPO 4 ⋅0.5 H 2 O precursor and with (VO) 2 P 2 O 7 as an active high‐temperature phase, are used as catalysts for the oxidation of alkanes. VOHPO 4 ⋅0.5 H 2 O is prepared from VOPO 4 ⋅2 H 2 O using 1‐octanol, 3‐octanol, 2‐butanol, or 2‐methyl‐1‐propanol as both solvent and reducing agent. With 1‐octanol, the reaction temperature was found to be crucial in obtaining a high yield of the precursor phase. At temperatures of 160 °C or greater, a solution containing V 4+ ions formed in preference to VOHPO 4 ⋅0.5 H 2 O. However, VOHPO 4 ⋅0.5 H 2 O formation can be achieved above 160 °C by carrying out the reduction process in the presence of a small amount of vanadium phosphate material, which effectively acts as a templating seed. The use of this seeding concept is shown to have a dramatic effect on the morphology of the final activated catalyst. In contrast, when 3‐octanol is used, solely VO(H 2 PO 4 ) 2 is generated, except in the presence of a vanadium phosphate seed where significant amounts of VOHPO 4 ⋅0.5 H 2 O can also be formed. Furthermore, VO(H 2 PO 4 ) 2 can be transformed to VOHPO 4 ⋅0.5 H 2 O by heating at reflux with an alcohol in the presence of VOHPO 4 ⋅0.5 H 2 O precursor seeds. The findings reported herein show that both the phase composition and morphology of vanadium phosphates can be influenced by the use of seeds during the preparation process.
Soluble Epoxide Hydrolase in Aged Female Mice and Human Explanted Hearts Following Ischemic Injury (2021)

Myocardial infarction (MI) accounts for a significant proportion of death and morbidity in aged individuals. The risk for MI in females increases as they enter the peri-menopausal period, generally occurring in middle-age. Cytochrome (CYP) 450 metabolizes N-3 and N-6 polyunsaturated fatty acids (PUFA) into numerous lipid mediators, oxylipids, which are further metabolised by soluble epoxide hydrolase (sEH), reducing their activity. The objective of this study was to characterize oxylipid metabolism in the left ventricle (LV) following ischemic injury in females. Human LV specimens were procured from female patients with ischemic cardiomyopathy (ICM) or non-failing controls (NFC). Female C57BL6 (WT) and sEH null mice averaging 13-16 months old underwent permanent occlusion of the left anterior descending coronary artery (LAD) to induce myocardial infarction. WT (wild type) mice received vehicle or sEH inhibitor, trans-4-[4-(3-adamantan-1-yl-ureido)-cyclohexyloxy]-benzoic acid (<i>t</i>AUCB), in their drinking water ad libitum for 28 days. Cardiac function was assessed using echocardiography and electrocardiogram. Protein expression was determined using immunoblotting, mitochondrial activity by spectrophotometry, and cardiac fibre respiration was measured using a Clark-type electrode. A full metabolite profile was determined by LC-MS/MS. sEH was significantly elevated in ischemic LV specimens from patients, associated with fundamental changes in oxylipid metabolite formation and significant decreases in mitochondrial enzymatic function. In mice, pre-treatment with <i>t</i>AUCB or genetic deletion of sEH significantly improved survival, preserved cardiac function, and maintained mitochondrial quality following MI in female mice. These data indicate that sEH may be a relevant pharmacologic target for women with MI. Although future studies are needed to determine the mechanisms, in this pilot study we suggest targeting sEH may be an effective strategy for reducing ischemic injury and mortality in middle-aged females.
Atezolizumab in combination with bevacizumab enhances antigen-specific T-cell migration in metastatic renal cell carcinoma (2016)

Anti-tumour immune activation by checkpoint inhibitors leads to durable responses in a variety of cancers, but combination approaches are required to extend this benefit beyond a subset of patients. In preclinical models tumour-derived VEGF limits immune cell activity while anti-VEGF augments intra-tumoral T-cell infiltration, potentially through vascular normalization and endothelial cell activation. This study investigates how VEGF blockade with bevacizumab could potentiate PD-L1 checkpoint inhibition with atezolizumab in mRCC. Tissue collections are before treatment, after bevacizumab and after the addition of atezolizumab. We discover that intra-tumoral CD8(+) T cells increase following combination treatment. A related increase is found in intra-tumoral MHC-I, Th1 and T-effector markers, and chemokines, most notably CX3CL1 (fractalkine). We also discover that the fractalkine receptor increases on peripheral CD8(+) T cells with treatment. Furthermore, trafficking lymphocyte increases are observed in tumors following bevacizumab and combination treatment. These data suggest that the anti-VEGF and anti-PD-L1 combination improves antigen-specific T-cell migration.
Evaluation MUMIE - Online math education aerospace engineering 2010-2011 (2011)

This report gives an overview of the development and experiences of using Mumie [1] at TU Delft during the academic year 2010-2011. Mumie is an e-learning platform that can be used for mathematical courses and acquired the interest of TU Delft at the beginning of 2009 in order to be used in their first years mathematical courses, in particular Linear Algebra . To see if Mumie could be successfully used at TU Delft, a pilot experiment was held under Aerospace Engineering students for a small part of the LA course. The outcome of this pilot was good, around 70% of the students recommended to use Mumie for the course, so further development of Mumie at TU Delft continued and is discussed in this report. Earlier reports on the development of Mumie at TU Delft can be found at the Mumie wiki [2]. Section 2 gives an update on the progress that has been made since the pilot. In Section 3 there is an overview of the student survey and grades for 2010/2011. Finally, in Section 4 conclusions are drawn from the survey results and student grades, together with a discussion and points of improvement for the future. Throughout this report some terms will be used that you might not be familiar with: AE the study Aerospace Engineering at TU Delft LA the Linear Algebra course at TU Delft CS the Computer Science course at TU Delft VWO this is highest level in the Dutch high school system
Trastuzumab Therapy for 9 Weeks vs 1 Year for Human Epidermal Growth Factor 2-Positive Breast Cancer—Reply (2018)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Oncology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Oncology journal
Design and Analysis of Convolutional Neural Network for RF Signal Modulation Classification for In-Orbit Deployment (2021)

To effectively transmit data to and from satellites requires a complex and robust RF communication system. Using adaptive link techniques, several different types of signal modulations may be used to maximize satellite efficiency depending on a variety of unexpected channel impairments. We propose a neural network algorithm capable of learning these RF signal modulations using a supervised learning technique designed for low power, high-efficiency in-orbit deployment. Thus, as signal modulation changes, a receiving satellite would be able to recognize this modulation update without adjustment from an operator, or any delay due to control signal transmission.The work presented demonstrates a convolutional neural network (CNN) capable of learning and recognizing a set of modulation schemes commonly used to transmit RF information. We are capable of recognizing the modulation scheme from the I and Q data channels directly, with no preprocessing or data conversion required other than breaking the incoming signal into a set of uniform normalized samples. We perform a network design and size analysis, showing that we can obtain reasonably high accuracy using networks with a relatively low number of trainable parameters. Given that a user of a system such as this may wish to receive a signal using a modulation scheme that the network has not previously learned, we demonstrate that transfer learning can learn new modulation schemes by retraining only the fully connected layers in the CNN. Thus, this type of network would excel in outer space deployment using high-efficiency transfer learning hardware. Modulation recognition can be performed through rapid feedforward computation, and the CNN training process is significantly simplified when learning new modulations is required.
OS0109 Behavior of droplet on Si wafer with rotational acceleration (2016)

Droplet behavior with rotational acceleration was experimentally investigated. The experiments were carried out using hydrophilic (Type-A) and hydrophobic (Type-B) wafers as the test pieces. Deformation and movement of droplet on wafer by rotational acceleration were visualized by a video camera. Characteristics of droplet migration were evaluated. Two types of droplet migration patterns were observed. The droplet on TypeA was deformed in the direction of acceleration, and the elongation with trace leaving on the wafer was observed. On the other hand, droplet on TypeB was moved without large deformation. This characteristic observed on the occasion of migration.
Preparation of cellulose nanofiltration membranes and their removal of typical pollutants from drinking water (2021)

Abstract Cellulose membranes have the advantages of good hydrophilicity, excellent mechanical properties, and biodegradability. Therefore, they are the first choice to replace petroleum polymer membranes. In this study, cellulose (BC) and chitosan (CS) were used as raw materials, and N-methylmorpholine-N-oxide (NMMO) was used as solvent. A new kind of cellulose nanofiltration membrane (BC-NFM), cellulose/chitosan nanofiltration membrane (BC/CS-NFM), and interfacial polymerized cellulose/chitosan composite nanofiltration membrane (IP-BC/CS-NFM) were successfully prepared by NaOH hydrolysis and chloroacetic acid carboxymethylation modification, piperazine (PIP), and 1,3,5-trimellitic chloride (TMC) interfacial polymerization, respectively. These two methods were used for the preparation of cellulose nanofiltration membranes for the first time.We also studied their structure, separation performance and their capacity to remove typical pollutants. The results showed that obvious holes appeared on the surface of the nanofiltration membrane obtained by alkali hydrolysis and chloroacetic acid carboxymethylation modification, and the cross-section showed a spongelike structure. The surface of the nanofiltration membrane obtained by interfacial polymerization formed a rough and dense separation layer. The rejection rates of the three kinds of nanofiltration membranes were all over 30% for monovalent salt ions, over 60% for divalent salt ions, over 92% for methyl orange, and over 98% for methyl blue. They had good removal effects for typical pollutants in drinking water.