gebhart/patrepeval huggingface dataset:
Periprosthetic Fracture of the Acetabulum after Total Hip Arthroplasty* (1996)

Eleven patients who had sustained a periprosthetic fracture of the acetabulum at a mean of 6.2 years (range, one month to thirteen years) after a total hip arthroplasty were managed at our institution between 1985 and 1991. Five patients had a fracture of the medial wall; three, a fracture of the posterior column; two, a transverse fracture; and one, a fracture of the anterior column. Six fractures were displaced by two millimeters or more. Eight fractures were caused by blunt trauma or a fall, and three occurred spontaneously. A fracture was classified as type 1 if the acetabular component was clinically and radiographically stable (eight patients) and as type 2 if the component was unstable (three patients). One patient, who had a displaced type-2 fracture of the posterior column, died of an associated intrapelvic vascular injury. The other two patients who had a type-2 fracture were managed with revision of the acetabular component without supplemental plate fixation, immediately after the diagnosis of the fracture. The eight patients who had a type-1 fracture initially were managed with limitation of weight-bearing or modification of activity; in six of these patients, the fracture united without additional treatment. The ten surviving patients were followed for a mean of sixty-two months after the fracture. Eight of these patients-including four in whom a type-1 fracture had united after non-operative treatment-had a revision of the acetabular component because of pain, loosening, or non-union by the time of the most recent follow-up. Two patients (one of whom had a type-1 fracture and the other, a type-2 fracture) had multiple revisions of the acetabular component; both had supplemental internal fixation with a plate. All ten patients ultimately had a stable, functioning prosthesis. We conclude that periprosthetic acetabular fractures are associated with a poor prognosis with regard to the survival of the acetabular component but that it is possible to achieve union and to salvage a functional prosthesis in patients who have sustained such a fracture.
Rate‐reduction transcoding design for wireless video streaming (2002)

Abstract Owing to the heterogeneity existing in wireless video streaming, such as terminal capabilities, network conditions, user preferences, and the natural environment in which a user is located, rate‐reduction transcoding is usually necessary to adjust the coding rate to the available channel bandwidth. We begin this paper by reviewing existing approaches and addressing several issues related to transcoding. Next, two types of rate‐reduction coding techniques are studied. The first type is based on standard coding schemes and specifically considers transcoding from MPEG‐2 to MPEG‐4 with a reduced spatial resolution. A method for drift compensation based on an intrarefresh technique is also presented. The second type of scheme is a rate‐reduction transcoder that makes use of frame‐level R‐D information that has already been extracted at the server before transmission. This R‐D‐based approach can be applied to architecture simplification, rate control, frame dropping control, and channel adaptive transcoding. We conclude this paper by pointing out that transcoding is an integral part of wireless video streaming because it provides a flexible interface between the wired network and the wireless network. Copyright © 2002 John Wiley &amp; Sons, Ltd.
The Senstivity of Detection-Limited D-Values to the Magnitude Distribution (2017)

Summary Microseismic measurements are detection-limited and this poses problems for the recovery of statistical summaries of the event sets, such as the magnitude (b-value) and spatial (D-value) distributions. We present case study examples, together with a straightforward method to identify situations where the recovered spatial and magnitude distributions are not independent. We highlight the type of interpretation difficulty that can occur, and which is partly mitigated by the proposed method.
Ceramic Resonators Using BGS Waves (1992)

The BGS wave has generally a large electromechanical coupling factor and a characteristic of complete reflection at stress-free edges of substrates. Therefore, a broad-band super-miniature resonator with a small capacitance ratio can be made utilizing the free-edge reflection property of a BGS wave. A BGS wave resonator using PZT was developed for use as a resonator for an additional trap at f as (adjacent sound carrier frequency) in VIF circuits of TV sets and VCRs. Testing as a trap device in VIF showed that this device has better properties than LC trap circuits.
Depletion of lubricant impregnated in a cavity of lubricant-infused surface (2021)

A lubricant-infused surface (LIS) has been widely studied due to its potential in various industrial fields. However, the outermost lubricant layer of LIS is highly vulnerable to external shear force, which gradually degrades the slippery property. In this study, the shear flow-induced depletion of lubricant impregnated in a single cavity was experimentally investigated. The lubricant-filled three-dimensional cavity was exposed to a laminar channel flow. Temporal variations in the interfacial menisci inside the cavity were directly observed. The result showed that the depletion rate of lubricant is gradually decreased and eventually reaches a quasi-steady state after a long lapse of time. A large-scale vortex is formed near the lubricant meniscus and largely weakens the shear stress exerted on the meniscus. The formation of a large-scale vortex dramatically slows down the depletion rate of the impregnated lubricant. In addition, the effect of cavity geometry on the depletion of the lubricant impregnated in a biomimetic LIS was examined. The results revealed that a cavity with a smaller opening ratio (r/R) has better sustainability and less lubricant depletion. The present results would provide valuable insight into the design of a robust LIS system for effective and sustainable drag reduction and other applications.
Brain metabolism and autoantibody titres predict functional impairment in systemic lupus erythematosus (2015)

The presence of serum DNRAbs can account for some aspects of brain dysfunction in patients with SLE, and the addition of regional measurements of resting brain metabolism improves the assessment and precise attribution of central nervous system manifestations related to SLE.
Acceptor site(s) for T cell-replacing factor (TRF) on B lymphocytes. I. TRF-substituting activity of anti-TRF acceptor site(s) antibody in the triggering of B cells. (1982)

Abstract Antiserum raised in TRF-non-responder (DBA/2Ha × BALB/c)(DC)F, male mice against TRF-responder parental BALB/c B cells induced augmented primary IgM anti-heterologous erythrocyte antibody responses when i.v. injected in combination with suboptimal doses of antigen into TRF high-response animals. Although injection of the antiserum alone induces a small but significant polyclonal PFC response, the antiserum acts synergistically with antigen to produce enhanced antigen-specific PFC responses. BALB/c nu/nu mice were used to demonstrate the ability of DCF1 male anti-BALB/c-B cell antiserum to substitute for helper T cell activity in the induction of a primary anti-SRBC IgM PFC response. The T cell-replacing character of the antiserum was further substantiated by the striking augmentation in BALB/c mice of anti-DNP IgM PFC responses to DNP-D-GL (a potent B cell tolerogen) toward which no T cell activity occurs. Thus, the DCF1 male anti-BALB/c-B cell antiserum contains antibody that is capable of substituting for TRF activity. Moreover, the fact that the F(ab’)2 fragment of the antibody reacted selectively with B cells as analyzed by the FACS, and that the augmenting activity of the antibody was also effectively absorbed out by B cells but not by T cells, further implies that the reactivity of the antibody is B cell specific. Finally, in order to test whether the TRF acceptor site(s) detected by this antibody is identical to or closely associated with the Lyb-3 (and -5 and -7) molecules, the effect of the antiserum on primary anti-SRBC responses was examined in CBA/N mice and other control strains of mice, including DBA/2Ha. The fact that injection of CBA/ N mice with SRBC in combination with the antiserum produced a greater than 10-fold increase in anti-SRBC PFC, just as in BALB/c mice, indicated that enhancement of the anti-SRBC responses is clearly due to a specific reaction of this antibody with a component that is different from Lyb-3 (and -5 and -7), which is absent in CBA/N mice. In contrast to this, administration of the antiserum failed to augment the anti-SRBC PFC responses in DBA/ 2Ha mice, indicating that the augmenting effect is clearly due to a specific reaction with a component that is absent in DBA/2Ha mice. An alloantiserum containing anti-TRF acceptor site(s) antibody that has B cell-triggering activity may provide us with the experimental strategy necessary for characterization of the TRF acceptor site(s) on B cells and for analysis of the fine mechanism of B cell triggering that occurs via this site.
Minimizing Voltage Loss in Wide-Bandgap Perovskites for Tandem Solar Cells (2018)

Perovskites with bandgaps between 1.7 and 1.8 eV are optimal for tandem configurations with crystalline silicon (c-Si) because they facilitate efficient harvest of solar energy. In that respect, achieving a high open-circuit voltage (VOC) in such wide-bandgap perovskite solar cells is crucial for a high overall power conversion efficiency (PCE). Here, we provide key insights into the factors affecting the VOC in wide-bandgap perovskite solar cells. We show that the influence of the hole transport layer (HTL) on VOC is not simply through its ionization potential but mainly through the quality of the perovskite–HTL interface. With effective interface passivation, we demonstrate perovskite solar cells with a bandgap of 1.72 eV that exhibit a VOC of 1.22 V. Furthermore, by combining the high-VOC perovskite solar cell with a c-Si solar cell, we demonstrate a perovskite–Si four-terminal tandem solar cell with a PCE of 27.1%, exceeding the record PCE of single-junction Si solar cells.
ParLearning 2018 Invited Talk 3 (2018)

Provides an abstract of the presentation and may include a brief professional biography of the presenter. The complete presentation was not made available for publication as part of the conference proceedings.
MEMS near-DC to RF capacitive series switches (2003)

This paper presents a novel type of RF-MEMS capacitive series switch. Its insertion loss and isolation can be separately optimised. Moreover, its actual performances closely fit the theoretical characteristics allowing an accurate and precise design. We will present electromechanical and high frequency simulations as well as C-V and S-parameters measurements clearly showing the improved characteristics of the new "boosted switch". We demonstrate the design flexibility, e.g. arbitrary and precise choice of the up- and down-capacitances in the respective ranges [0.1-0.3pF] and [1-30pF]. Insertion Loss lower than 0.3dB (including 1 μm thick, 2*400μm long Al feeding line losses) and Isolation higher than 10dB in the frequency range 1-10GHz have been measured. The capacitance ratio Cdown/Cup, fixed at 11 for the conventional design in our technology, has been boosted up to 600 with the new structure using the same materials and comparable dimensions.
Characterization of Fiber Bragg Gratings in Multicore Fibers Using Quantitative Phase Imaging (2018)

A quantitative phase imaging method is applied to characterize fiber Bragg gratings in multicore fibers. Digital image processing techniques are developed to overcome the difficulties arising from the short period of the fiber Bragg gratings.
Trimethylselenonium Hydroxide (2001)

[44124-85-8] C3H10OSe (MW 141.09) InChI = 1S/C3H10OSe/c1-5(2,3)4/h4H,1-3H3 InChIKey = KBZDZTFKFVPAGB-UHFFFAOYSA-N (methylating agent for relatively nonnucleophilic heteroatoms1) Solubility: sol H2O, MeOH. Form Supplied in: not commercially available. Analysis of Reagent Purity: solution concentration can be determined by titration with 0.1 N hydrochloric acid. Preparative Method: a solution in methanol–water can be generated by addition of Silver(I) Oxide (1 equiv) to a solution of trimethylselenonium iodide (1.3 equiv).1 Typical concentrations of ≈0.7 N are obtained. Handling, Storage, and Precautions: the solution is stable at temperatures below 10 °C, undergoing ≈5% decomposition after 1 month. The solution is alkaline, and therefore would not be compatible with acidic solvents. Since one of the byproducts of the reaction is dimethyl selenide, reactions should be carried out in a fume hood.
Tunable Filtering of Chemical Signals in a Simple Nanoscale Reaction-Diffusion Network (2007)

We study numerically the filtering capabilities of a nanoscale network of two micrometer-sized containers joined by a nanotube, one of which hosts an enzymatic chemical reaction. Spatiotemporal chemical signals of substrate molecules are injected into the network. The substrate propagates by diffusion and reacts with enzymes distributed in the network prior to the injections. The dimensions of the network are tailored in a way that the transport and enzymatic reaction rates are comparable in size, a situation in which the overall behavior is highly influenced by the geometry and topology of the network. This property is crucial for the functionality of the filter developed in here. It is demonstrated that input signals can be classified in a crude way using a simple setup (a two-container network) and that the classification can be tuned by changing the geometry of the network (the length of the tube connecting the two containers). The filter device we investigate can also be viewed as a primitive chemistry-based computational element in the sense that the information encoded in the signals is processed using chemical reactions. In particular, it is demonstrated that the two-container device may filter out signals based on the average injection frequency.
Facile batch mode process for high capacity rechargeable nickel-zinc microbatteries (2017)

This paper reports a facile approach for batch mode fabrication of millimeter-scale Ni-Zn batteries that is facilitated by unconventional structural materials and fabrication options. Micro electrodischarge machining (μEDM) is used to define arrays of cavities in foils of Ni and Zn. The cathode and electrolyte materials are incorporated using a self-aligned damascene method. The fabricated batteries have a footprint of =0.048 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , a nominal voltage of 1.7 V, and a typical capacity of =63 μAh. These batteries provide sufficient power and energy density for millimeter-scale autonomous microsystems that are being actively developed for health and wellness, as well as environmental applications. The fabrication process can be scaled to manufacture large arrays of microbatteries.
Mass-Transport-Limited Electrodeposition of High-Surface-Area Coatings for Surface Acoustic Wave Sensor Technology (1999)

The sensitivity of surface acoustic wave (SAW) sensors has been enhanced by increasing the active surface area of these devices, Electrodepositions of Ni, Pd, and Pt in a mass-transport-limited mode with trace foreign metals yield highly dendritic crystal structures of uniform macroscopic thickness. The concentration of metal ions, supporting electrolyte, agitation, and additives greatly impact the crystal morphology of the deposit. This methodology can be used simply and economically to provide high-area films in selective regions.
Does the strain hardening modulus of glassy polymers scale with the flow stress? (2008)

Abstract Using a generic coarse‐grained bead‐spring model, Hoy and Robbins reproduced important experimental observations on strain hardening, specifically the generally observed Gaussian strain hardening response and its dependence on network density and temperature. Moreover, their simulation results showed that the strain hardening response at different strain rates collapses to a single curve when scaled to the value of the flow stress, a phenomenon that has not yet been verified experimentally. In the present study, the proposed scaling law is experimentally investigated on a variety of polymer glasses: poly(methyl methacrylate), poly(phenylene ether), polycarbonate, polystyrene, and poly(ethylene terephthalate)‐glycol. For these polymers, true stress–strain curves in uniaxial compression were collected over a range of strain rates and temperatures and scaled to the flow stress. It was found that, generally, the curves do not collapse on a mastercurve. In all cases, the strain hardening modulus is observed to increase linearly, but not proportionally to the flow stress. The experimental data, therefore, unambiguously demonstrate that the proposed scaling law does not apply within the range of temperature and strain rate covered in this study. © 2008 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 46: 2475–2481, 2008
Synthesis of Carbocyclic Analogues of Thymidine (2003)

A new route towards an enantiomerically pure carbocyclic 2'-deoxyribonucleoside precursor was developed. After coupling with a nucleobase the product is easily accessible for further modifications at the 3'-hydroxy group.
Therapeutic Efficacy of Adenoviral-Mediated p53 Gene Transfer Is Synergistically Enhanced by Combined Use of Antisense Oligodeoxynucleotide Targeting Clusterin Gene in a Human Bladder Cancer Model (2005)

To establish a more effective therapeutic strategy against advanced bladder cancer, we investigated the effects of combined treatment with antisense (AS) oligodeoxynucleotide (ODN) targeting the anti-apoptotic gene clusterin and adenoviral-mediated p53 gene transfer (Ad5CMV-p53) using the human bladder cancer KoTCC-1 model. Clusterin expression in KoTCC-1 cells was highly upregulated by Ad5CMV-p53 treatment; however, AS clusterin ODN treatment further suppressed clusterin expression in KoTCC-1 cells after Ad5CMV-p53 treatment. AS clusterin ODN treatment synergistically enhanced the cytotoxic effect of Ad5CMV-p53, and DNA fragmentation characteristic of apoptosis was observed only after combined treatment with AS clusterin ODN and Ad5CMV-p53, but not after treatment with either agent alone. Administration of AS clusterin ODN and Ad5CMV-p53 into nude mice resulted in a significant inhibition of KoTCC-1 tumor growth as well as lymph node metastases compared to administration of either agent alone. Furthermore, combined treatment with AS clusterin ODN, Ad5CMV-p53, and cisplatin completely eradicated KoTCC-1 tumors and lymph node metastases in 60% and 100% of mice, respectively. These findings suggest that combined treatment with AS clusterin ODN and Ad5CMV-p53 could be a novel strategy to inhibit bladder cancer progression, and that further additional use of a chemotherapeutic agent may substantially enhance the efficacy of this combined regimen.
Abstract 14264: Weight Loss-Induced Blood Pressure Reduction: Different Mechanisms Between a Calorie Restricted Diet and Exercise (2011)

Objective: The present study compared the effectiveness of a mild calorie restricted diet (D) alone, exercise (EX) alone and a combination of D+EX on weight loss-induced blood pressure (BP) reducti...
A Critical Role for IL-18 in the Proliferation and Activation of NK1.1+CD3− Cells (1998)

Like IL-12, IFN-gamma-inducing factor/IL-18 has been shown to stimulate T cells for IFN-gamma production and growth promotion. Considering the NK-stimulatory capacity of IL-12, we investigated the effect of IL-18 on NK lineage cells. A CD4- CD8- surface Ig- Ia- fraction of freshly prepared C57BL/6 spleen cells proliferated strikingly in response to combinations of IL-12 + IL-18 or IL-2 + IL-18, but not to the individual cytokines or IL-2 + IL-12. Cells proliferating in response to IL-2 + IL-18 were NK1.1+ CD3-, whereas IL-12 + IL-18-responsive cells were NK1.1- CD3-. Restimulation of the former cells with IL-12 + IL-18 or the latter cells with IL-2 + IL-18 resulted in the generation of NK1.1- CD3- or NK1.1+ CD3- cells, respectively. Moreover, a NK1.1+ CD3- CD4- CD8- surface Ig- Ia- population isolated from spleen cells was found to form NK1.1+ CD3- or NK1.1- CD3- blasts by stimulation with IL-2 + IL-18 or IL-12 + IL-18, respectively, and the NK1.1 positivity on these blasts was again reversed after restimulation with an alternative combined stimulus. Both types of blasts produced enormously large amounts of IFN-gamma in response to IL-12 + IL-18 and exhibited strikingly high levels of NK activity. These results indicate that IL-18 plays an obligatory role in inducing proliferation and activation of NK1.1+ CD3- CD4- CD8- cells and that the expression of the NK1.1 marker is reversible, depending on the cytokine used for stimulation in combination with IL-18.
Design of clinical trials to assess diabetes treatment: Minimum duration of continuous glucose monitoring data to estimate time‐in‐ranges with the desired precision (2021)

The presented approach can be used to both compute the uncertainty of time-in-ranges and determine the minimum duration of a trial to achieve the desired precision. An online tool to facilitate its implementation is made freely available to the clinical investigator.
Modified Uridines with C5-methylene Substituents at the First Position of the tRNA Anticodon Stabilize UG Wobble (2008)

The genetic code is deciphered by the anticodons of tRNAs,whichcarryanaminoacidatthe3 end,bindtoaspecificcodonin the mRNA, and transfer their amino acid to the growingpolypeptide chain on the ribosome. In codon-anticodon inter-actions in the ribosome, the second and third bases (positions35 and 36) of the anticodon base pair with the second and firstbases of the codon, respectively, following Watson-Crick(WC)
Gait motion analysis in the unrestrained condition of trans-femoral amputee with a prosthetic limb (2012)

Trans-femoral amputees must regain moving pattern by refined rehabilitation program using ground reaction forces, joint angles and joint moments applied on a prosthetic limb. On the other hand, understanding those loads and kinematic variables is indispensable for gait analysis based on the biomechanical consideration of trans-femoral amputees. However, conventional prosthetic gait training systems cannot measure long continuous walking motions. In this paper, ground reaction forces and kinematic parameters applied on trans-femoral prosthesis are measured by the prosthetic gait motion analysis system using mobile force plate and attitude sensor for the unrestrained gait measurement. As a result of the experiments, the patterns of antero-posterior axis ground reaction forces and joint moments about the medio-lateral axis are remarkably different among the five activities. Finally, the effectiveness of the developed prosthetic gait training system to consider biomechanics and kinematics in trans-femoral prosthesis is validated.