gebhart/patrepeval huggingface dataset:
A new sensorless method for switched reluctance motor drives (1998)

This paper describes a new method for indirect sensing of the rotor position in switched reluctance motors (SRMs) using pulse width modulation voltage control. The detection method uses the change of the derivative of the phase current to detect the position where a rotor pole and stator pole start to overlap, giving one position update per energy conversion. As no a priori knowledge of motor parameters is required (except for the numbers of stator and rotor poles), the method is applicable to most SRM topologies in a wide power and speed range and for several inverter topologies. The method allows modest closed-loop dynamic performance. To start up the motor, a feedforward stepping method is used which assures robust startup (even under load) from standstill to a predefined speed at which closed-loop sensorless operation can be applied. Experimental results demonstrate the robust functionality of the method with just one current sensor in the inverter, even with excitation overlap, and the sensorless operation improves with speed. The method is comparable to the back-EMF position estimation for brushless DC motors in principle, performance and cost. A detailed operation and implementation of this scheme is shown, together with steady-state and dynamic transient test results.
The Effect of Polymer Chain Length and Surface Density on the Adhesiveness of Functionalized Polymersomes (2004)

Giant cell-like polymer vesicles, polymersomes, made from the diblock copolymer poly(ethylene oxide)-polybutadiene (PEO-PBD), have bilayer structures similar to the cell membrane but have superior and tunable properties for storage and stability. We have modified the terminal hydroxyl of the hydrophilic block with biotin-lysine (biocytin), a biologically derived group that imparts specific adhesiveness to a polymer colloid coated with avidin. The functionalized polymer will form vesicles, either on its own or when mixed with unmodified block copolymers that also form vesicles. The incorporation and mixing of the functionalized polymer into vesicle bilayers is measured using a fluorescent version ofbiocytin with confocal microscopy. The fluorescence signal associated with the vesicle is in proportion with the concentration of functional polymer added during vesicle construction. The adhesiveness of polymer vesicles containing functionalized biotinylated polymer to avidin coated microspheres is measured with micropipet aspiration. Two types of polymer vesicles were constructed: one where the functionalized polymer (molecular weight (MW), 10400 Da) was longer than the surrounding unfunctionalized polymer (MW, 3600 Da) and one where the functionalized polymer (MW, 10400 Da) was the same length as the unfunctionalized polymer. In all cases, the avidin-biotin bonds form kinetically trapped crossbridges that impart little tension as they form but require significantly more tension to break. The relative length of the functionalized polymer on the surface of the vesicle is an important determinant for the adhesion of a polymer vesicle but not for the adsorption of soluble avidin. Greater adhesion strengths are seen where the functionalized polymer is longer than the surrounding polymer. The concentration of functionalized polymer at which adhesion is maximal depends on the relative lengths of the polymers. When the functionalized polymer is the same length as the surface brush of the polymersome membrane, the critical tension is maximal at 10 mol % functionalized polymer concentration. However, when the biocytin groups are attached to a polymer which is larger than the surface brush, the critical tension is maximal at 55 mol % functionalized polymer. These results indicate that polymer mixing and length can control the interfacial adhesion of polymer brushes and must be understood to tune polymersome adhesiveness.
Regioregular Polymers from Biobased (R)-1,3-Butylene Carbonate (2021)

We present (R)-1,3-butylene carbonate (R-BC) as a biorenewable monomer for the preparation of semicrystalline aliphatic polycarbonates. This conversion is achieved by using enantiomerically pure, biobased (R)-(−)-1,3-butanediol (bio-BG) as a renewable feedstock. Ring-opening polymerization from select catalysts at low temperatures can yield regioregular poly((R)-1,3-butylene carbonate) (R-PBC) with semicrystalline properties (Xreg = > 0.99; Tm = 72 °C). Along with the R-enantiomeric polymer, the alternate stereochemical polymers (using S- and racemic BC) were investigated. Our analysis shows that the highest level of crystallinity is achieved with regioregular, biobased R-PBC compared to the petrol-based S- and racemic congeners. This work shows the potential of stereochemically pure bio-BG as a starting material for semicrystalline, aliphatic carbonates when high regioregularity is achieved in the polymer microstructure. The synthesis and thermal characterization of regioregular butylene carbonate polymers are described in detail.
Role of pixel design and emission wavelength on the light extraction of nitride-based micro-LEDs (2023)

Micro-light emitting diodes (µ-LEDs) suffer from a drastic drop in internal quantum efficiency that emerges with the miniaturization of pixels down to the single micrometer size regime. In addition, the light extraction efficiency (LEE) and far field characteristics change significantly as the pixel size approaches the wavelength of the emitted light. In this work, we systematically investigate the fundamental optical properties of nitride-based µ-LEDs with the focus on pixel sizes from 1 µm to 5 µm and various pixel sidewall angles from 0<sup>∘</sup> to 60<sup>∘</sup> using finite-difference time-domain simulations. We find that the LEE strictly increases with decreasing pixel size, resulting in a LEE improvement of up to 45% for a 1 µm pixel compared to a 20 µm pixel. The ideal pixel sidewall angle varies between 35<sup>∘</sup> and 40<sup>∘</sup>, leading to a factor of 1.4 enhancement with respect to vertical pixel sidewalls. For pixel sizes in the order of 2 µm and smaller, a substantial transition of far field properties can be observed. Here, the far field shape depends severely on the pixel sidewall angle and affects the LEE within a solid angle of ±15<sup>∘</sup>. Moreover, we investigate the impact of emission wavelength and observe major differences in optical characteristics for blue, green and red emitting pixels, which is relevant for real-world applications. Finally, we discuss the implications of the assumptions we made and their significance for the design of µ-LEDs.
Towards Federated Learning-Enabled Visible Light Communication in 6G Systems (2021)

&lt;div&gt;Visible light communication is envisaged as a promising enabling technology for sixth generation (6G) and beyond networks. It was introduced as a key enabler for reliable massive-scale connectivity, mainly thanks to its simple and low-cost implementation which require minor variations to the existing indoor lighting systems. The key features of VLC allow offloading data traffic from the current congested radio frequency (RF) spectrum in order to achieve effective short-range, high speed, and green communications. However, several challenges prevent the realization of the full potentials of VLC, namely the limited modulation bandwidth of light emitting diodes, the interference resulted from ambient light, the effects of optical diffuse reflection, the non-linearity of devices, and the random receiver orientation. Meanwhile, centralized machine learning (ML) techniques have exhibited great potentials in handling different challenges in communication systems. Specifically, it has been recently shown that ML algorithms exhibit superior capabilities in handling complicated network tasks, such as channel equalization, estimation and modeling, resources allocation, opportunistic spectrum access control, non-linearity compensation, performance monitoring, detection, decoding/encoding, and network optimization. Nevertheless, concerns relating to privacy and communication overhead when sharing raw data of the involved clients with a server constitute major bottlenecks in large-scale implementation of centralized ML techniques. This has motivated the emergence of a new distributed ML paradigm, namely federated learning (FL). This method can reduce the cost associated with transferring the raw data, and preserve clients privacy by training ML model locally and collaboratively at the clients side. Thus, the integration of FL in VLC networks can provide ubiquitous and reliable implementation of VLC systems. Based on this, for the first time in the open literature, we provide an overview about VLC technology and FL. Then, we introduce FL and its integration in VLC networks and provide an overview on the main design aspects. Finally, we highlight some interesting future research directions of FL that are envisioned to boost the performance of VLC systems. &lt;/div&gt;
Supplementary Figure 3 from Inhibitors of Deacetylases Suppress Oncogenic KIT Signaling, Acetylate HSP90, and Induce Apoptosis in Gastrointestinal Stromal Tumors (2023)

Supplementary Figure 3 from Inhibitors of Deacetylases Suppress Oncogenic KIT Signaling, Acetylate HSP90, and Induce Apoptosis in Gastrointestinal Stromal Tumors
High‐Throughput Screen of Natural Product Extracts in A Yeast Model of Polyglutamine Proteotoxicity (2014)

Proteins with expanded polyglutamine (polyQ) segments cause a number of fatal neurodegenerative disorders, including Huntington's disease (HD). Previous high-throughput screens in cellular and biochemical models of HD have revealed compounds that mitigate polyQ aggregation and proteotoxicity, providing insight into the mechanisms of disease and leads for potential therapeutics. However, the structural diversity of natural products has not yet been fully mobilized toward these goals. Here, we have screened a collection of ~11 000 natural product extracts for the ability to recover the slow growth of ΔProQ103-expressing yeast cells in 384-well plates (Z' ~ 0.7, CV ~ 8%). This screen identified actinomycin D as a strong inhibitor of polyQ aggregation and proteotoxicity at nanomolar concentrations (~50-500 ng/mL). We found that a low dose of actinomycin D increased the levels of the heat-shock proteins Hsp104, Hsp70 and Hsp26 and enhanced binding of Hsp70 to the polyQ in yeast. Actinomycin also suppressed aggregation of polyQ in mammalian cells, suggesting a conserved mechanism. These results establish natural products as a rich source of compounds with interesting mechanisms of action against polyQ disorders.
A G‐protein‐coupled 130 kDa phospholipase C isozyme, PLC‐β4, from the particulate fraction of bovine cerebellum (1993)

A 130 kDa PLC isozyme was purified from the particulate fraction of bovine cerebellum. This PLC was recognized by a polyclonal antiserum generated against the purified 97 kDa PLC-beta 4. Reconstitution of the purified 130 kDa PLC with the membranes of C6 Bu-1 cells in the presence of GTP gamma S or AlF4- resulted in PLC activation as well as the association of PLC with the membranes. Both the association and activation were revoked when the membrane was washed with 2 M KCl. The 97 kDa PLC-beta 4 did not associate with membranes. These data suggest that the 130 kDa PLC is the intact form of PLC-beta 4 the activity of which is likely to be regulated by a G-protein on the membrane.
10 000‐fold concentration increase in proteins in a cascade microchip using anionic ITP by a 3‐D numerical simulation with experimental results (2011)

This paper describes both the experimental application and 3-D numerical simulation of isotachophoresis (ITP) in a 3.2 cm long "cascade" poly(methyl methacrylate) (PMMA) microfluidic chip. The microchip includes 10 × reductions in both the width and depth of the microchannel, which decreases the overall cross-sectional area by a factor of 100 between the inlet (cathode) and outlet (anode). A 3-D numerical simulation of ITP is outlined and is a first example of an ITP simulation in three dimensions. The 3-D numerical simulation uses COMSOL Multiphysics v4.0a to concentrate two generic proteins and monitor protein migration through the microchannel. In performing an ITP simulation on this microchip platform, we observe an increase in concentration by over a factor of more than 10,000 due to the combination of ITP stacking and the reduction in cross-sectional area. Two fluorescent proteins, green fluorescent protein and R-phycoerythrin, were used to experimentally visualize ITP through the fabricated microfluidic chip. The initial concentration of each protein in the sample was 1.995 μg/mL and, after preconcentration by ITP, the final concentrations of the two fluorescent proteins were 32.57 ± 3.63 and 22.81 ± 4.61 mg/mL, respectively. Thus, experimentally the two fluorescent proteins were concentrated by over a factor of 10,000 and show good qualitative agreement with our simulation results.
Effect of number and position of EBNA-1 binding sites in Epstein-Barr virus oriP on the sites of initiation, barrier formation, and termination of replication (1993)

DNA replication intermediates of three plasmids containing all or part of a modified Epstein-Barr virus cis-acting plasmid maintenance region (oriP) were examined to further investigate oriP function. Replication intermediates were analyzed in vivo and in vitro by neutral-neutral two-dimensional gel electrophoresis. The major functional components of the wild-type oriP are a 140-bp dyad symmetry region (single dyad) and 20 tandem copies of a repeat with a 30-bp consensus sequence (family of repeats). A modified oriP was constructed by replacing the family of repeats with three tandem copies of the single dyad (D. A. Wysokenski and J. L. Yates, J. Virol. 63:2657-2666, 1989). Initiation was observed in vivo near the single dyad in the modified oriP, as seen in the wild-type oriP (T. A. Gahn and C. L. Schildkraut, Cell 58:527-535, 1989), but was not observed near the tandem dyads. A replication barrier and termination were observed near the tandem dyads and were similar to those observed at the family of repeats of the wild-type oriP (Gahn and Schildkraut, Cell 58:527-535, 1989). In vitro experiments indicate that the viral trans-acting factor EBNA-1 contributes to efficient barrier formation at the tandem dyads as observed in the family of repeats of the wild-type oriP (V. Dhar and C. L. Schildkraut, Mol. Cell. Biol. 11:6268-6278, 1991). The tandem dyads thus appear to function in a manner similar to the family of repeats. There are significant structural differences between the family of repeats and tandem dyads. The relationship between the number and relative positions of EBNA-1 binding sites in relation to the functions of the family of repeats and the dyad symmetry element is discussed.
Dynamic Sensor Planning and Control for Optimally Tracking Targets (2003)

In this paper, we present an approach to the problem of actively controlling the configuration of a team of mobile agents equipped with cameras so as to optimize the quality of the estimates derived from their measurements. The issue of optimizing the robots' configuration is particularly important in the context of teams equipped with vision sensors, since most estimation schemes of interest will involve some form of triangulation. We provide a theoretical framework for tackling the sensor planning problem, and a practical computational strategy inspired by work on particle filtering for implementing the approach. We then extend our framework by showing how modeled system dynamics and configuration space obstacles can be handled. These ideas have been applied to a target tracking task, and demonstrated both in simulation and with actual robot platforms. The results indicate that the framework is able to solve fairly difficult sensor planning problems online without requiring excessive amounts of computational resources.
Analytical and Experimental Evaluation of Various Active Suspension Alternatives for Superior Ride Comfort and Utilization of Autonomous Vehicles (2020)

Abstract Autonomous vehicles (AVs) give the driver opportunity to engage in productive or pleasure-related activities, which will increase AV’s utility and value. It is anticipated that many AVs will be equipped with active suspension extended with road disturbance preview capability to provide the necessary superior ride comfort resulting in almost steady work or play platform. This article deals with assessing the benefits of introducing various active suspensions and related linear quadratic regulator (LQR) controls in terms of improving the work/leisure ability. The study relies on high-performance shaker rig-based tests of a group of 44 drivers involved in reading/writing, drawing, and subjective ride comfort rating tasks. The test results indicate that there is a threshold of root-mean-square vertical acceleration, below which the task execution performance is similar to that corresponding to standstill conditions. For the given, relatively harsh road disturbance profile, only the fully active suspension with road preview control can suppress the vertical acceleration below the above critical superior comfort threshold. However, when adding an active seat suspension, the range of chassis suspension types for superior ride comfort is substantially extended and can include semi-active suspension and even passive suspension in some extreme cases that can, however, lead to excessive relative motion between the seat and the vehicle floor. The design requirements gained through simulation analysis, and extended with cost and packaging requirements related to passenger car applications, have guided design of two active seat suspension concepts applicable to the shaker rig and production vehicles.
A protocol for quantifying cardiogenic oscillations in dynamic 129Xe gas exchange spectroscopy: The effects of idiopathic pulmonary fibrosis (2018)

The spectral parameters of hyperpolarized <sup>129</sup> Xe exchanging between airspaces, interstitial barrier, and red blood cells (RBCs) are sensitive to pulmonary pathophysiology. This study sought to evaluate whether the dynamics of <sup>129</sup> Xe spectroscopy provide additional insight, with particular focus on quantifying cardiogenic oscillations in the RBC resonance. <sup>129</sup> Xe spectra were dynamically acquired in eight healthy volunteers and nine subjects with idiopathic pulmonary fibrosis (IPF). <sup>129</sup> Xe FIDs were collected every 20 ms (T<sub>E</sub> = 0.932 ms, 512 points, dwell time = 32 μs, flip angle ≈ 20°) during a 16 s breathing maneuver. The FIDs were pre-processed using the spectral improvement by Fourier thresholding technique (SIFT) and fit in the time domain to determine the airspace, interstitial barrier, and RBC spectral parameters. The RBC and gas resonances were fit to a Lorentzian lineshape, while the barrier was fit to a Voigt lineshape to account for its greater structural heterogeneity. For each complex resonance the amplitude, chemical shift, linewidth(s), and phase were calculated. The time-averaged spectra confirmed that the RBC to barrier amplitude ratio (RBC:barrier ratio) and RBC chemical shift are both reduced in IPF subjects. Their temporal dynamics showed that all three <sup>129</sup> Xe resonances are affected by the breathing maneuver. Most notably, several RBC spectral parameters exhibited prominent oscillations at the cardiac frequency, and their peak-to-peak variation differed between IPF subjects and healthy volunteers. In the IPF cohort, oscillations were more prominent in the RBC amplitude (16.8 ± 5.2 versus 9.7 ± 2.9%; P = 0.008), chemical shift (0.43 ± 0.33 versus 0.083 ± 0.05 ppm; P < 0.001), and phase (7.7 ± 5.6 versus 1.4 ± 0.8°; P < 0.001). Dynamic <sup>129</sup> Xe spectroscopy is a simple and sensitive tool that probes the temporal variability of gas exchange and may prove useful in discerning the underlying causes of its impairment.
Clinical Robustness of Accelerated and Optimized Abdominal Diffusion-Weighted Imaging (2017)

Diffusion-weighted imaging of the abdomen can be considerably accelerated and optimized integrating the SMS technique and a 3D diagonal diffusion mode. In a large patient cohort, this approach proved of superior image quality while maintaining similar ADC values compared with standard DWI. This technique seems applicable for daily clinical routine.
Effect of Development of Habituation to Restraint Stress on Hypothalamic Noradrenaline Release and Adrenocorticotropin Secretion (1995)

The effect of repeated stress has been studied on noradrenaline release in the hypothalamic paraventricular nucleus and on adrenocorticotropin levels. Rats were stressed by 20-min immobilization once a day for 5 days. On day 6 they were exposed to the same stress or to a different one (ether vapors for 2 min). Immobilization and ether stress increased noradrenaline release in naive rats (271 +/- 43 and 197 +/- 9%, respectively) and raised adrenocorticotropin levels, showing activation of the hypothalamus-pituitary axis. Repeated daily restraint did not modify basal noradrenaline or adrenocorticotropin levels. The further immobilization session on day 6 did not change noradrenaline levels at any observation time (20-120 min). The adrenocorticotropin response was still present, although significantly reduced. In repeatedly restrained rats, exposure to ether vapors induced a maximal increase in noradrenaline level similar to that observed in naive rats, although prolonged. In these rats the adrenocorticotropin response did not differ from that in acutely stressed rats. These results suggest that habituation may develop to a stressful stimulus leading to suppression of the hypothalamic noradrenergic response and that this phenomenon is stress specific. Moreover, modifications of noradrenaline release in the paraventricular nucleus are not solely responsible for the adrenocorticotropin response during stress, suggesting that other pathways and/or neurotransmitters are involved too.
Axial leakage current reduction in a 12-cavity rising-sun relativistic magnetron with a &#x201C;F&#x201D; transparent cathode (2014)

Summary form only given. We report a variant of transparent cathode, `F' transparent cathode for reduction of axial leakage current in a 12-cavity rising-sun relativistic magnetron. The leakage current reduction is achieved by increasing the thickness of transparent cathode tips in azimuthal direction at the end. Particle-in-cell (PIC) simulation of a 12-cavity rising-sun relativistic magnetron demonstrated the advantage of `F' transparent cathode. With `F' transparent cathode, the electronic efficiency in 12-c avity rising-sun relativistic magnetron can be as high as 70% while the leakage current can be reduced around 50% compared to transparent cathode. Further research on `F' transparent cathode are now going on.
Comparison of leaf structure of Bermuda grass grown under two habitats (2010)

Through observing the leaf cross sections of five varieties of Bermuda grass grown in rural area soil and vegetation concrete,the thickness of leaves,upper epidermis and lower epidermis,the diameters of vascular bundle(rosette structure)in the main vein of Bermuda grass were compared.The results showed:Except for Nanjing bermudagrass,the thickness of leaves of the other four varieties(Common hulled,Jackpot,040459/680 and Xinnong No.1)grown in vegetation were bigger than those grown in rural area soil;Except for 040459/680 bermudagrass,the thickness of leaf upper epidermis and lower epidermis of the other four varieties grown in vegetation were bigger than those grown in rural area soil;The diameters of vascular bundle(rosette structure)in the main vein of five varieties grown under the two habitats varied differently.