MP23-08 SHORT PULSE VS. LONG PULSE ABLATION WITH THE THULIUM FIBER LASER, AN IN VITRO STUDY (2023)

You have accessJournal of UrologyCME1 Apr 2023MP23-08 SHORT PULSE VS. LONG PULSE ABLATION WITH THE THULIUM FIBER LASER, AN IN VITRO STUDY Francois Soto Palou, Robert Medairos, Junqin Chen, Jodi Antonelli, Michael Lipkin, Glenn Preminger, and Pei Zhong Francois Soto PalouFrancois Soto Palou More articles by this author , Robert MedairosRobert Medairos More articles by this author , Junqin ChenJunqin Chen More articles by this author , Jodi AntonelliJodi Antonelli More articles by this author , Michael LipkinMichael Lipkin More articles by this author , Glenn PremingerGlenn Preminger More articles by this author , and Pei ZhongPei Zhong More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000003248.08AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: The thulium fiber laser (TFL) is becoming of interest to Urologists due to its unique properties. The TFL pulse profile consists of rectangular pulses, designed for enhancing photothermal ablation. Energy for each pulse may be modified by altering pulse duration or peak power. Our aim for this study is to compare short pulse (SP) versus long pulse (LP) for common 10 W dusting settings using the TFL platform. METHODS: All tests were conducted using an IPG Photonics TLR-50 W TFL system and a 200 μm fiber on “soft” (5:2) Begostone phantoms. The most popular 10 W dusting settings (Figure 1) among endourologists familiar with TFL were evaluated.[1] Four different standoff distances (0.2 mm, 0.5 mm 1 mm, 2 mm), and a clinically significant scanning speed of 1 mm/sec was used. The pulse profiles were altered for each energy setting to produce a short pulse (SP) and a long pulse (LP) design. The laser fiber was scanned in a 15 mm straight line with a 3D positioning system across a polished and submerged Begostone surface. Ablation volumes were quantified by optical coherence tomography (OCT). RESULTS: Overall, SP provided greater ablation volume when compared to LP. The greatest difference observed between SP and LP was at 1J/10 Hz and SD of 0.2 mm (2.51 mm3 vs. 0.35 mm3) and this difference was statistically significant (p<0.005). Out of the 20 performed trials there were only two instances in which LP outperformed SP in terms of ablation volume: 0.4J/25 Hz at SD of 2 mm (0 mm3 vs. 0.15 mm3) and 0.2J/50 Hz at SD of 0.2 mm (0.79 mm3 vs 0.81 mm3). In the latter case, however, the difference was not found to be statistically significant (p=0.7). CONCLUSIONS: TFL short pulse profile offers superior trough ablation volumes than long pulse during dusting under clinically relevant scanning speed of 1 mm/s with a time average power of 10 W. [1] Sierra A, Corrales M, Piñero A, Traxer O. Thulium fiber laser pre-settings during ureterorenoscopy: Twitter's experts' recommendations. World J Urol. 2022;40(6):1529-1535. doi:10.1007/s00345-022-03966-9. Source of Funding: N/A © 2023 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 209Issue Supplement 4April 2023Page: e308 Advertisement Copyright & Permissions© 2023 by American Urological Association Education and Research, Inc.MetricsAuthor Information Francois Soto Palou More articles by this author Robert Medairos More articles by this author Junqin Chen More articles by this author Jodi Antonelli More articles by this author Michael Lipkin More articles by this author Glenn Preminger More articles by this author Pei Zhong More articles by this author Expand All Advertisement PDF downloadLoading ...