gebhart/patrepeval huggingface dataset:
Curved optimal delaunay triangulation (2018)

Meshes with curvilinear elements hold the appealing promise of enhanced geometric flexibility and higher-order numerical accuracy compared to their commonly-used straight-edge counterparts. However, the generation of curved meshes remains a computationally expensive endeavor with current meshing approaches: high-order parametric elements are notoriously difficult to conform to a given boundary geometry, and enforcing a smooth and non-degenerate Jacobian everywhere brings additional numerical difficulties to the meshing of complex domains. In this paper, we propose an extension of Optimal Delaunay Triangulations (ODT) to curved and graded isotropic meshes. By exploiting a continuum mechanics interpretation of ODT instead of the usual approximation theoretical foundations, we formulate a very robust geometry and topology optimization of Bézier meshes based on a new simple functional promoting isotropic and uniform Jacobians throughout the domain. We demonstrate that our resulting curved meshes can adapt to complex domains with high precision even for a small count of elements thanks to the added flexibility afforded by more control points and higher order basis functions.
Strong enhancement of vibrational relaxation by Watson-Crick base pairing (2004)

We have studied the ultrafast dynamics of NH-stretch vibrational excitations in Watson-Crick base pairs consisting of adenine and uracil derivatives. To estimate the influence of the A:U hydrogen bonding on the vibrational dynamics, we have also studied the uracil derivative in monomeric form. The vibrational relaxation of the NH-stretching mode is found to occur much faster in the Watson-Crick base pair than in monomeric uracil. From the delay dependence of the transient vibrational spectra, it can be concluded that both in base-paired and monomeric uracil, the energy relaxation takes place in two steps, the first step being a rapid transfer of energy from the NH-stretching mode to an accepting mode, the second step the relaxation of this accepting mode. The transient spectra show evidence that in the base pair the hydrogen bond between the nucleobases acts as the accepting mode, and that the hydrogen bonding between the bases is responsible for the extremely fast vibrational relaxation in this system.
Influence of the soot property uncertainties in temperature and volume-fraction measurements by two-colour pyrometry (1994)

A sensitivity analysis of the two-colour pyrometry technique for calculation of soot temperature T and volume fraction fv is presented. Two different combustion environments are exemplified for high (fv approximately=10-5) and low (fv approximately=10-7) soot concentration regimes. The calculations are carried out taking into account particle shape, different expressions for monochromatic emissivity, optical property variations, size distribution of soot particles and a finite light-detection bandwidth. The results indicate which spectral range, for the choice of the ( lambda 1, lambda 2) wavelengths employed in the emission measurements, and computing algorithm, for the reckoning of the T values, can be appropriated to guarantee a lower a priori uncertainty in the T and fv calculated values. Results stress the evidence that T and fv values are critically sensitive to the complex refractive index, m=n-ik, and that they are irrelevantly influenced by the probability distribution of particle size. The critical theoretical influence of the type of fuel, characterized by a different soot hydrogen/carbon ratio, upon the inferred fv values is assessed. Determinations of temperature values with ( lambda 1, lambda 2) measurement wavelengths above 1.2 mu m is demonstrated to be invalidated by an uncertainty contribution of at least 20 K in the regime fv approximately=10-5 and 100 K in the regime fv approximately=10-7.
REDUCED EXPRESSION OF beta-SUBUNIT OF NA,K-ATPASE IN HUMAN CLEAR-CELL RENAL CELL CARCINOMA (1999)

These results suggest that the beta-subunit may regulate the Na,K-ATPase activity in vivo. Diminished Na,K-ATPase activity in conjunction with the reduced beta-subunit level is associated with the clear-cell RCC phenotype.
Modularity in Organic Solid State and Supramolecular Chemistry (2006)

Connection between the concept of modularity and how it relates to both organic solid state and supramolecular chemistry is discussed. It is demonstrated how the interrelationship between the three areas can be exploited to control chemical reactivity in the solid state. Specifically, it is shown how these areas can be used to achieve and fine-tune reactivity in organic solids. How modularity relates to other chemical systems, as well as to other areas of technology, is also discussed.
Effects of temperature and humidity cycling on the strengths of textile reinforced carbon/epoxy composite materials (1993)

Results are presented from an experimental evaluation of the combined effects of temperature and humidity cycling on AS4/3501-6 composites (unstitched, Kevlar 29 stitched, and S-2 glass stitched uniweave fabric) and AS4/E905L composites (2-D, S-2 glass stitched 2-D, and 3-D braided fabric). The AS4/3501-6 uniweave material had a quasi-isotropic layup, whereas the AS4/E905L materials were braided in a (+/-30 deg/0 deg)(sub s) orientation. Data presented include compression strengths and compression-compression fatigue results for uncycled composites and cycled composites (160, 480, 720, and 1280 cycles from 140 deg F at 95 percent relative humidity to -67 deg F). To observe the presence of microcracking within the laminates, photomicrographs were taken of each material type at the end of each cycling period. Microcracks were found to be more prevalent within stitched laminates, predominantly around individual stitches. The glass stitched laminates showed significant microcracking even before cycling. Less microcracking was evident in the Kevlar stitched materials, whereas the unstitched uniweave material developed microcracks only after cycling. The 3-D braid did not develop microcracks. The static compression strengths of the unstitched and Kevlar stitched uniweave materials were degraded by about 10 percent after 1280 temperature/humidity cycles, whereas the reduction in compression strength for the glass stitched uniweave was less than 3 percent. The reduction in compression strength for the glass stitched 2-D braid was less than 8 percent. The unstitched 2-D and 3-D braids did not lose strength from temperature/humidity cycling. The compression-compression fatigue properties of all six material types were not affected by temperature/humidity cycling.
Chimeric spike mRNA vaccines protect against Sarbecoviru s challenge in mice (2021)

The emergence of SARS-CoV in 2003 and SARS-CoV-2 in 2019 highlights the need to develop universal vaccination strategies against the broader <i>Sarbecovirus</i> subgenus. Using chimeric spike designs, we demonstrate protection against challenge from SARS-CoV, SARS-CoV-2, SARS-CoV-2 B.1.351, bat CoV (Bt-CoV) RsSHC014, and a heterologous Bt-CoV WIV-1 in vulnerable aged mice. Chimeric spike mRNAs induced high levels of broadly protective neutralizing antibodies against high-risk Sarbecoviruses. In contrast, SARS-CoV-2 mRNA vaccination not only showed a marked reduction in neutralizing titers against heterologous Sarbecoviruses, but SARS-CoV and WIV-1 challenge in mice resulted in breakthrough infection. Chimeric spike mRNA vaccines efficiently neutralized D614G, UK B.1.1.7., mink cluster five, and the South African B.1.351 variant of concern. Thus, multiplexed-chimeric spikes can prevent SARS-like zoonotic coronavirus infections with pandemic potential.
ChemInform Abstract: A Highly Diastereoselective Synthesis of α‐Hydroxy‐β‐amino Acid Derivatives via a Lewis Acid Catalyzed Three‐Component Condensation Reaction. (2011)

Abstract A highly diastereoselective and very efficient method to prepare title compounds is reported.
Development Of A 14 Fr. Size Hemopump (2005)

One of the latest advancements in miniature blood pump technology is under development by Nimbus, Inc. This device is a smaller version of the Hemopump currently undergoing clinical trials in the United States. Compared to the original 21 Fr. size (7 mm diameter) Hemopump the smaller device is 14 Fr. (4.6 mm diameter) in size, but has roughly the same blood flow capacity. Motivation to create the 14 Fr. pump is for treatment of smaller patients or ones who have sclerotic or small torturous vessels that prevent placement of the 21 Fr. device. Also, the 14 Fr. can be introduced percutaneously, and this has implications for more widespread usage by non-surgeons. This paper outlines the major physical characteristics of the 14 Fr. pump and summarizes its current development status.
Synthesis and Antimuscarinic Properties of Quinuclidin-3-yl 1,2,3,4-Tetrahydroisoquinoline-2-carboxylate Derivatives as Novel Muscarinic Receptor Antagonists (2005)

In the course of continuing efforts to develop potent and bladder-selective muscarinic M3 receptor antagonists, quinuclidin-3-yl 1-aryl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives and related compounds were designed as conformationally restricted analogues of quinuclidin-3-yl benzhydrylcarbamate (8). Binding assays with rat muscarinic receptor subtypes revealed that the quinuclidin-3-yl 1-aryl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives showed high affinities for the M3 receptor, and selectivity for the M3 receptor over the M2 receptor. Of these derivatives, (+)-(1S,3'R)-quinuclidin-3'-yl 1-phenyl-1,2,3,4-tetrahydroisoquinoline-2-carboxylate monohydrochloride (9b) exhibited almost the same inhibitory activity against bladder contraction to that of oxybutynin (1), and more than 10-fold selectivity for bladder contraction versus salivary secretion, demonstrating that 9b may be useful for the treatment of symptoms associated with overactive bladder without having side effects such as dry mouth.
A Compact, 114-GHz, High-efficiency Power Amplifier in a 250-nm InP HBT Process (2022)

This work presents a single-stage D-band power amplifier (PA) with high power density and high efficiency at 114 GHz in a 250-nm Indium Phosphide (InP) technology. A pseudo-differential common-base (CB) stage and low-loss coupled-line balun (CLB) are designed to deliver 17.6-dBm output power and 32.7% power-added efficiency (PAE) at 114GHz. Occupying only 0.024mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , the design achieves the highest output power to area ratio, (P <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">sat</inf> /Area), power gain to area ratio, (Gain/Area), and high efficiency among published D-band PAs.
An environment for collaborative content acquisition and editing by coordinated ubiquitous devices (2005)

Digital content is not only stored by servers on the Internet, but also on various embedded devices belonging to ubiquitous networks. In this paper, we propose a content processing mechanism for use in an environment enabling collaborative acquisition of embedded digital content in real-world situations. We have developed a network management device that makes it possible to acquire embedded content using coordinated ubiquitous devices. The management device actively configures a network that includes content-providing devices and browsing devices to permit sharing of various items with digital content. We also developed a Functional web mechanism for processing embedded web content in the real-world without a keyboard. This mechanism adds various functions to conventional web content. These functions are activated by messages from a Field in a content processing device. We construct a practical prototype system, which is simple enough for children to use, that we called the "Virtual Insect Catcher". Through a test with 48 children, we demonstrated that this system can be used to acquire embedded web content, retrieve related content from the Internet, and then create new web content. We will also describe the proposed mechanism and the system testing.
Laser marking on soda-lime glass by laser-induced backside wet etching with two-beam interference (2016)

For crack-free marking of glass materials, a beam-scanning laser-induced backside wet etching (LIBWE) process by a beam spot with a fine periodic structure was examined. The fine periodic structure was produced within a beam spot by means of a Mach–Zehnder interferometer incorporated to the optical setup for the beam-scanning LIBWE. A fine structure with a period of 9 µm was observed within the microstructures with a diameter of ca. 40 µm fabricated by a laser shot under double-beam irradiation, and they could be homogeneously fabricated within an area of 800 × 800 µm. The area filled with the microstructures, including fine periodic structures, could be observed in high contrast under a diffuse, on-axis illumination that was used in commercial QR code readers.
Gallium Oxide Nanorods: Novel, Template‐Free Synthesis and High Catalytic Activity in Epoxidation Reactions (2014)

Gallium oxide nanorods with unprecedented small dimensions (20-80 nm length and 3-5 nm width) were prepared using a novel, template-free synthesis method. This nanomaterial is an excellent heterogeneous catalyst for the sustainable epoxidation of alkenes with H2 O2 , rivaling the industrial benchmark microporous titanosilicate TS-1 with linear alkenes and being much superior with bulkier substrates. A thorough characterization study elucidated the correlation between the physicochemical properties of the gallium oxide nanorods and their catalytic performance, and underlined the importance of the nanorod morphology for generating a material with high specific surface area and a high number of accessible acid sites.
Recombination hotspots in soybean [ Glycine max (L.) Merr.] (2023)

Recombination allows for the exchange of genetic material between two parents, which plant breeders exploit to make improved cultivars. This recombination is not distributed evenly across the chromosome. Recombination mostly occurs in euchromatic regions of the genome and even then, recombination is focused into clusters of crossovers termed recombination hotspots. Understanding the distribution of these hotspots along with the sequence motifs associated with them may lead to methods that enable breeders to better exploit recombination in breeding. To map recombination hotspots and identify sequence motifs associated with hotspots in soybean [Glycine max (L.) Merr.], two biparental recombinant inbred lines populations were genotyped with the SoySNP50k Illumina Infinium assay. A total of 451 recombination hotspots were identified in the two populations. Despite being half-sib populations, only 18 hotspots were in common between the two populations. While pericentromeric regions did exhibit extreme suppression of recombination, 27% of the detected hotspots were located in the pericentromeric regions of the chromosomes. Two genomic motifs associated with hotspots are similar to human, dog, rice, wheat, drosophila, and arabidopsis. These motifs were a CCN repeat motif and a poly-A motif. Genomic regions spanning other hotspots were significantly enriched with the tourist family of mini-inverted-repeat transposable elements that resides in <0.34% of the soybean genome. The characterization of recombination hotspots in these two large soybean biparental populations demonstrates that hotspots do occur throughout the soybean genome and are enriched for specific motifs, but their locations may not be conserved between different populations.
Enolase of Streptococcus pneumoniae Binds Human Complement Inhibitor C4b-Binding Protein and Contributes to Complement Evasion (2012)

Streptococcus pneumoniae (pneumococcus) is a pathogen that causes severe local and life-threatening invasive diseases, which are associated with high mortality rates. Pneumococci have evolved several strategies to evade the host immune system, including complement to disseminate and to survive in various host niches. Thus, pneumococci bind complement inhibitors such as C4b-binding protein (C4BP) and factor H via pneumococcal surface protein C, thereby inhibiting the classical and alternative complement pathways. In this study, we identified the pneumococcal glycolytic enzyme enolase, a nonclassical cell surface and plasminogen-binding protein, as an additional pneumococcal C4BP-binding protein. Furthermore, we demonstrated that human, but not mouse, C4BP bound pneumococci. Recombinant enolase bound in a dose-dependent manner C4BP purified from plasma, and the interaction was reduced by increasing ionic strength. Enolase recruited C4BP and plasminogen, but not factor H, from human serum. Moreover, C4BP and plasminogen bound to different domains of enolase as they did not compete for the interaction with enolase. In direct binding assays with recombinant C4BP mutants lacking individual domains, two binding sites for enolase were identified on the complement control protein (CCP) domain 1/CCP2 and CCP8 of the C4BP α-chains. C4BP bound to the enolase retained its cofactor activity as determined by C4b degradation. Furthermore, in the presence of exogenously added enolase, an increased C4BP binding to and subsequently decreased C3b deposition on pneumococci was observed. Taken together, pneumococci specifically interact with human C4BP via enolase, which represents an additional mechanism of human complement control by this versatile pathogen.
Active materials embedded in photonic crystals and coupled to electromagnetic radiation (2006)

A calculational scheme is presented to model the interaction of light with active dielectric media, represented by four-level atomic materials, surrounded by photonic crystals. Optically pumped lasing is studied in three model systems: a Fabry-Perot cavity, a line of defects in a two-dimensional square lattice of rods, and a cylindrical photonic crystal. Field profiles and conversion efficiencies are calculated for these systems. It is shown that high conversion efficiency can be achieved for large regions of active material in the cavity, as well as for a single fluorescent atom in a hollow-core cylindrical photonic crystal, suggesting designs for ultralow-threshold lasers and ultrasensitive biological sensors.
Publisher Correction: Intensity distribution segmentation in ultrafast Doppler combined with scanning laser confocal microscopy for assessing vascular changes associated with ageing in murine hippocampi (2022)

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Folding of carp parvalbumin studied by equilibrium and kinetic circular dichroism spectra (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFolding of carp parvalbumin studied by equilibrium and kinetic circular dichroism spectraKunihiro Kuwajima, Atsushi Sakuraoka, Shoichi Fueki, Michio Yoneyama, and Shintaro SugaiCite this: Biochemistry 1988, 27, 19, 7419–7428Publication Date (Print):September 1, 1988Publication History Published online1 May 2002Published inissue 1 September 1988https://doi.org/10.1021/bi00419a037RIGHTS & PERMISSIONSArticle Views73Altmetric-Citations47LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alertsclose Get e-Alerts
Matched filtering in natural and artificial neural networks (1999)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text A. K. Zherebko and V. R. Lutsiv, "Matched filtering in natural and artificial neural networks," J. Opt. Technol. 66, 822- (1999) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Síntesis de sulfuros de metales de transición no soportados y su actividad catalítica en la reacción de HDS profunda. Synthesis of metal sulfides unsupported transition and their catalytic activity in the reaction of deep-HDS (2016)

Sulfuros de metales de transicion no soportados fueron sintetizados usando el metodo del poliol, controlando algunas variables relevantes durante el protocolo de sintesis, con el fin de aumentar el area superficial y mejorar la actividad catalitica en la reaccion de hidrodesulfuracion profunda. El control ajustado de la velocidad de adicion de los sustratos, y la temperatura de reflujo, usando como solvente etilenglicol, permitio mejorar el area superficial del sulfuro de molibdeno, aun cuando para los demas metales no se observaron los cambios en area superficial esperados. Se obtuvieron sulfuros de metales de transicion de los grupos VIb, VIIb y VIII, y sistemas bimetalicos NiMoSx y CoMoSx, con el fin de observar el efecto sinergico en la reaccion catalitica de HDS. La actividad catalitica de sulfuros sintetizados, en un reactor tipo Batch, demostro que el catalizador mas activo es el sulfuro de renio y los sulfuros bimetalicos, usando como precursores Ni y Co sobre el sulfuro de molibdeno. Se observo un efecto sinergico por la presencia de estos metales, que modifica no solo la actividad en la reaccion de hidrodesulfuracion, sino ademas la selectividad, en funcion del metal promotor. Palabras clave : Sulfuros de metales de transicion, hidrodesulfuracion profunda, efecto sinergico, catalizador no soportado Abstract  Metal sulfides unsupported transition were synthesized using polyol method, some relevant variable for controlling the synthesis protocol, in order to increase the surface area and improve the catalytic activity in the reaction of deep hydrodesulphurization. Adjusted the speed of controlling addition of the substrates and the reflux temperature, using ethylene glycol as solvent, improved the surface area molybdenum sulfide, even if for other metals were not observed changes in surface area desired. Transition metal sulfides of VIb, VIIb and VIII groups, and bimetallic systems NiMoSx and CoMoSx were obtained; for the purpose of observe the synergistic effect in catalytic HDS. The catalytic activity of sulfides synthesized in a type batchreactor, showed that the most active catalyst is rhenium sulfide and bimetallic sulphides, using as precursors Ni and Co on molybdenum sulfide. A synergistic effect by the presence of these metals, modifying not only the activity in the hydrodesulphurization reaction, but also the selectivity, depending on the promoter metal is observed. Keywords: Transition metal sulfides, deep hydrodesulphurization, synergistic effect, unsupported catalyst