gebhart/patrepeval huggingface dataset:
PRIMARY PROSTATE CRYOABLATION: UPDATED RESULTS FROM 2558 PATIENTS TRACKED WITH THE COLD REGISTRY (2008)

You have accessJournal of Urology1 Apr 2008PRIMARY PROSTATE CRYOABLATION: UPDATED RESULTS FROM 2558 PATIENTS TRACKED WITH THE COLD REGISTRY Aaron E Katz, J Stephen Jones, David Ellis, Bryan Donnelly, Louis L Pisters, Martin Dineen, Stephen Scionti, Franco Lugnani, and David M Jackson Aaron E KatzAaron E Katz More articles by this author , J Stephen JonesJ Stephen Jones More articles by this author , David EllisDavid Ellis More articles by this author , Bryan DonnellyBryan Donnelly More articles by this author , Louis L PistersLouis L Pisters More articles by this author , Martin DineenMartin Dineen More articles by this author , Stephen SciontiStephen Scionti More articles by this author , Franco LugnaniFranco Lugnani More articles by this author , and David M JacksonDavid M Jackson More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(08)61158-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "PRIMARY PROSTATE CRYOABLATION: UPDATED RESULTS FROM 2558 PATIENTS TRACKED WITH THE COLD REGISTRY." The Journal of Urology, 179(4S), pp. 395–396 © 2008 by American Urological AssociationFiguresReferencesRelatedDetails Volume 179Issue 4SApril 2008Page: 395-396 Advertisement Copyright & Permissions© 2008 by American Urological AssociationMetricsAuthor Information Aaron E Katz More articles by this author J Stephen Jones More articles by this author David Ellis More articles by this author Bryan Donnelly More articles by this author Louis L Pisters More articles by this author Martin Dineen More articles by this author Stephen Scionti More articles by this author Franco Lugnani More articles by this author David M Jackson More articles by this author Expand All Advertisement PDF downloadLoading ...
Novel current sensor for PWM AC drives (1988)

A novel current sensor which determines the currents flowing in an inverter driven induction motor from observations of the pulse currents existing in the DC busbar of the PWM inverter is described. The sensor can determine the real part of the current, and, if the motor is supplying mechanical power, the current magnitude. It is low cost and easy to implement, and experimental results show good accuracy over a range of operating conditions.
PhysiologicAlarm Load on Medical/ Surgical Floors of a Community Hospital (2011)

It has been known to the public that high frequency of false and/or unnecessary alarms from patient
HAWQ (2014)

HAWQ, developed at Pivotal, is a massively parallel processing SQL engine sitting on top of HDFS. As a hybrid of MPP database and Hadoop, it inherits the merits from both parties. It adopts a layered architecture and relies on the distributed file system for data replication and fault tolerance. In addition, it is standard SQL compliant, and unlike other SQL engines on Hadoop, it is fully transactional. This paper presents the novel design of HAWQ, including query processing, the scalable software interconnect based on UDP protocol, transaction management, fault tolerance, read optimized storage, the extensible framework for supporting various popular Hadoop based data stores and formats, and various optimization choices we considered to enhance the query performance. The extensive performance study shows that HAWQ is about 40x faster than Stinger, which is reported 35x-45x faster than the original Hive.
Frequency dissemination at the 19th decimal place (2012)

Optical frequency transmission via phase-stabilized telecommunication fiber is currently the most precise technique available for disseminating frequencies. We summarize some key advances, results and applications for fiber networks spanning up to 1000 km.
Prototype Sparse Arrays for 3D Sonar Imaging System (2009)

A three dimensional sonar imaging system is under development for use by Navy divers for mine-field reconnaissance and mine-hunting systems. These divers require a small, low power, lightweight acoustic imaging system with high resolution for examining and disposing of underwater ordinance. Sparse array technology is being investigated to develop a sonar requiring the minimal number of signal processing channels while maintaining the beamwidth and sidelobe structure required for high resolution imaging. Beamwidth and sidelobe structure are examined as a function of transducer element count, channel bandwidth, and element location when optimized using various cost functions. Test results for a prototype line array evaluated in the NUWC Acoustic Test Facility are reported. For undersea acoustic minefield reconnaissance and mine hunting by divers, a handheld, low cost sonar system is needed. To achieve these goals, Teratech Corporation, of Burlington, MA, is designing and building a high-resolution, three-dimensional sonar
Cloaking, trapping and superlensing of lamb waves with negative refraction (2021)

We report on experimental and numerical implementations of devices based on the negative refraction of elastic guided waves, the so-called Lamb waves. Consisting in plates of varying thickness, these devices rely on the concept of complementary media, where a particular layout of negative index media can cloak an object with its anti-object or trap waves around a negative corner. The diffraction cancellation operated by negative refraction is investigated by means of laser ultrasound experiments. However, unlike original theoretical predictions, these intriguing wave phenomena remain, nevertheless, limited to the propagating component of the wave-field. To go beyond the diffraction limit, negative refraction is combined with the concept of metalens, a device converting the evanescent components of an object into propagating waves. The transport of an evanescent wave-field is then possible from an object plane to a far-field imaging plane. Twenty years after Pendry's initial proposal, this work thus paves the way towards an elastic superlens.
A comparison of the fragmentation patterns of 5‐fluoromethyl‐3,4‐disubstituted isoxazoles and 5‐methyl analogs (1993)

Abstract The influence of fluorine substitution on the fragmentation processes of some substituted isoxazoles has been studied by comparing the electron‐impact‐induced mass spectrometric behaviour of some 5‐monofluoromethyl‐3,4‐disubstituted isoxazoles with that of the corresponding 5‐methyl analogs. Some interesting and unusual cleavages have been detected and a rationale has been developed for them on the basis of metastable ion studies and accurate mass measurements. Evidence has been found of the influence of fluorine in the stabilization of molecular and fragment ions.
Radial Artery Loop Perforation with a Transient Arterio-Venous Fistula during Transradial Catheterization (2012)

Transradial access (TRA) is often selected as an alternative route for cardiac catheterization of patients with iliofemoral artery disease or excessive tortuosity. However, anatomical variations of the radial artery are relatively common; radial artery loop is the commonest radial anomaly associated with procedural failure. In this report, we present a case of radial artery loop detected during TRA, following perforation of the loop and creation of an arteriovenous fistula with a hydrophilic guide wire. The success of a conservative management strategy using local compression was demonstrated by repeat angiography at the time of cardiac catheterization from the contralateral brachial artery on the following day. As more operators shift practice toward TRA, the importance of this anatomic variant and its associated risk and management will grow and is highlighted in this report.
Variable Temperature Infrared Spectroscopy of Cytosine-Guanine Base Pairs: Tautomerism Versus Polarization (1992)

This report describes an infrared (IR) spectroscopic study of a model cytosine-guanine base pair. This base pair is part of a self-consistent experimental system based on lipophilic ribose derivatives of cytidine (C), guanosine (G) and O6-methylguanosine (O6MeG) that are soluble in non-aqueous, low dielectric solvents at appreciable concentrations. Previous experiments on this system have revealed different rotation dynamics for the amino bonds within the CG base pair, an observation that could be explained by the presence of rare tautomers (P.O. Lowdin, Reviews of Modern Physics 35,724 (1963)), or by mutual polarization of the base pairs (L.D. Williams, N.G. Williams and B.R. Shaw,J.Am.Chem.Soc. 112,829 (1990)). The IR spectra in the OH and NH stretching region indicate formation of hydrogen-bonded CG base pairs and self associates in 1,2-dichlorobenzene over a temperature range from 10 to 290K. Changes in the lineshapes and intensities of the IR bands with temperature correlate with phase transitions of the solvent, but no evidence is seen for an OH stretching band that would indicate the formation of hydroxyl tautomers within base pairs. Similarly, the relative intensities of the C = O stretching bands of CG in cyclohexane solution remain constant over this same temperature range, confirming that within the base pair, the tautomeric states of the bases remain essentially unperturbed in the 2-amino/6-keto form of G and the 2-keto/4-amino form of C. The spectra of O6-MeG aid in the band assignments, since this molecule is frozen in an equivalent of the 2-amino/6-hydroxyl tautomer, but without the OH group and its associated stretching band. We conclude that the probability of tautomerism does not appear to be sufficient to explain the different rotation dynamics for the two amino bonds of the CG base pair. Rather it is argued that mutual polarization within the base pair, which would increase the bond order of the amino bond of C within the base pair, can explain the results without the formation of unconventional tautomers.
Epigenomic Analysis of Multi-lineage Differentiation of Human Embryonic Stem Cells (2013)

Epigenetic mechanisms have been proposed as crucial for regulating mammalian development, but their precise function is only partially understood. To investigate the epigenetic control of embryonic development, we differentiated human embryonic stem cells into mesendoderm, neural progenitor cells, trophoblast-like cells, and mesenchymal stem cells and systematically characterized DNA methylation, chromatin modifications, and the transcriptome in each lineage. Strikingly, we found that promoters that are active in early developmental stages tend to be CG rich and mainly engage H3K27me3 upon silencing in non-expressing lineages. By contrast, promoters for genes expressed preferentially at later stages are often CG poor and employ DNA methylation upon repression. Interestingly, the early developmental regulatory genes are often located in large genomic domains that are generally devoid of DNA methylation in most lineages, as we termed DNA methylation valleys (DMVs). Our results suggest that distinct epigenetic mechanisms regulate early and late stages of ES cell differentiation.
Improved performance of top-emitting, oxide-confined VCSELs with self-aligned contact and Cu-plated heatsink (2005)

Vertical-cavity surface-emitting lasers (VCSELs) with a self-aligned top contact and copper-plated heatsink were fabricated and characterized. Thermal resistance was reduced by 44%, and output power and bandwidth were increased by 38% and 12% respectively.
Synthesis of π‐conjugated oligomer that can form metallo polymers (2002)

Abstract An oligo( p ‐phenylene vinylene) that contains terpyridine ligands has been synthesized. Upon addition of metal ions, a π‐conjugated metallo polymer is formed in which the well‐defined character of oligomers and the material properties of polymers are combined. © 2002 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 40: 4020–4023, 2002
Nitride-Based LEDs with an Insulating SiO[sub 2] Layer Underneath p-Pad Electrodes (2007)

We proposed a simple method to reduce the current crowding effect of nitride-based light emitting diodes (LEDs) without extra dry etching and refill. It was found that we can achieve much better current spreading by inserting an insulating layer between the epitaxial layer and the p-pad electrode. It was also found that we can enhance light output intensity by 22%. Furthermore, it was found that forward voltage only increased slightly from with the insertion of the layer. The reliability of the proposed LED is also good.
Synthesis and characterization of polystyrene‐poly(ethylene oxide)‐heparin block copolymers (1989)

The following corrections are to be noted: p. 3218 After Eq. (7) add: where A, ( n = 1,2,. . .) are the positive roots of Eq.
Cord blood monocyte–derived inflammatory cytokines suppress IL-2 and induce nonclassic “TH2-type” immunity associated with development of food allergy (2016)

Food allergy is a major health burden in early childhood. Infants who develop food allergy display a proinflammatory immune profile in cord blood, but how this is related to interleukin-4 (IL-4)/T helper 2 (T(H)2)-type immunity characteristic of allergy is unknown. In a general population-derived birth cohort, we found that in infants who developed food allergy, cord blood displayed a higher monocyte to CD4(+) T cell ratio and a lower proportion of natural regulatory T cell (nT(reg)) in relation to duration of labor. CD14(+) monocytes of food-allergic infants secreted higher amounts of inflammatory cytokines (IL-1β, IL-6, and tumor necrosis factor-α) in response to lipopolysaccharide. In the presence of the mucosal cytokine transforming growth factor-β, these inflammatory cytokines suppressed IL-2 expression by CD4(+) T cells. In the absence of IL-2, inflammatory cytokines decreased the number of activated nT(reg) and diverted the differentiation of both nT(reg) and naïve CD4(+) T cells toward an IL-4-expressing nonclassical TH2 phenotype. These findings provide a mechanistic explanation for susceptibility to food allergy in infants and suggest anti-inflammatory approaches to its prevention.
New Integer Normalized Carrier Frequency Offset Estimators (2015)

Carrier frequency offset (CFO) introduces spectrum misalignment of the transmit and receive filters, causing energy loss and distortion of received signal. A recent study presents an accurate signal model that incorporates these characteristics. However, CFO estimators in the existing literature were developed based on the signal models without these characteristics. This paper generalizes the accurate signal model with CFO to include timing offset and sampling offset and then studies what effects the accurate signal model bring to the CFO estimation and how to address them. We investigate different existing CFO estimators and find some of them lose their optimality under the accurate signal model. We also develop two new integer normalized CFO (ICFO) estimators under the accurate signal model using only one OFDM symbol; one of them is a pilot-aided estimator using both pilot and data and the other one is a blind estimator using data only. Compared with the existing approaches, both of the new estimators make better use of channel and energy loss information, thus yielding more accurate estimation. Furthermore, the proposed methods overcome the existing approaches' limitation to phase shift keying modulation. Simulation results corroborate the advantages of the new estimators. Analytical performance results are also provided for the proposed estimators.
Abstract 10200: Translational Research of Novel Angiogenic Peptide for Wound Healing Drug; From Discovery to Clinical Trial (2015)

We developed a novel cationic peptide, AG30/5C, with angiogenic properties. Since it has both angiogenic and antimicrobial actions, it might be a candidate peptide for wound healing drug. We conducted a physician-initiated clinical trial of AG30/5C for severe skin ulcer in patients as an open label study. The primary outcome is safety because it is first in human trial on early stage. AG30/5C was administered with patients with skin ulcer twice per day for two weeks, and ulcer size and Methicillin-Resistant Staphylococcus Aureus amount was quantified as a secondary outcome. Two patients was registered until now and the skin ulcer of first patient was completely cured after AG30/5C treatment. The Methicillin-Resistant Staphylococcus Aureus amount of both patients was decreased during the AG30/5C treatment. This result suggests the potential of AG30/5C as a wound healing drug, however, improvement of stability and cost efficiency are required toward drug development. Thus, we addressed to the metabolites of AG30/5C which can provide a further optimized compound, SR-0379. SR-0379 also enhanced proliferation, tube formation, migration and contraction on human dermal fibroblast cells via the PI3K-Akt-mTOR pathway through integrin-mediated interactions. We evaluated the effect of SR-0379 on two different would healing model in rats, the full-thickness defects in diabetic condition and an acutely infected wound with the full-thickness defects and inoculation with S aureus. Treatment of SR-0379 significantly accelerated the wound healing compared to that of FGF2. The beneficial effects of SR-0379 on wound healing would be explained by enhanced angiogenesis, granulation tissue formation, proliferation and antimicrobial activity. These results clearly demonstrated that SR-0379 may have a potential for drug development in wound repairing, in especially critical colonization condition. Based on these results, we now conducted the physician-initiated clinical trial for severe skin ulcer in patients as a double blind study.
Rapid Transformation of Protein-Caged Nanomaterials into Microbubbles As Bimodal Imaging Agents (2012)

We present a general method for converting colloidal nanomaterials into microbubbles as ultrasound contrast agents. Protein-caged nanomaterials, made either by self-assembled nanoparticles' protein corona or by fluorescent gold nanoclusters, can be rapidly transformed into microbubbles via a sonochemical route, which promote disulfide cross-linking of cysteine residues between protein-caged nanomaterials and free albumin during acoustic cavitation. The proposed methods yielded microbubbles with multiple functions by adjusting the original nanoparticle/protein mixture. We also showed a new dual-modal imaging agent of fluorescent gold microbubbles in vitro and in vivo, which can hold many potential applications in medical diagnostics and therapy.
Resolving the Process of Clathrin Mediated Endocytosis Using Correlative Light and Electron Microscopy (CLEM) (2019)

This chapter will present the computational approach of registering images from different modalities based on manual selection of matching pairs of landmarks. Here we will present an image registration workflow based on MATLAB’s image processing toolbox using the identification of sites of clathrin-mediated endocytosis by correlative light electron microscopy (CLEM) as an example. In the Appendix section, we will discuss the concept of image transformations and how to generate them based on pairs of landmarks. We will also learn how to fit a 2D Gaussian for a more accurate positioning of the landmarks.
Biliary reconstruction using the cystic duct in right lobe living donor liver transplantation (2004)

Suh, Kyung-Suk MD, PhD; Choi, Seok Ho MD; Yi, Nam-Joon MD, PhD; Kwon, Choon Hyuck MD; Lee, Kuhn Uk MD, PhD, FACS Author Information
Spectral monitoring at SwissFEL using a high-resolution on-line hard X-ray single-shot spectrometer (2021)

The performance and parameters of the online photon single-shot spectrometer (PSSS) at the Aramis beamline of the SwissFEL free-electron laser are presented. The device operates between the photon energies 4 and 13 keV and uses diamond transmission gratings and bent Si crystals for spectral measurements on the first diffraction order of the beam. The device has an energy window of 0.7% of the median photon energy of the free-electron laser pulses and a spectral resolution (full width at half-maximum) ΔE/E on the order of 10<sup>-5</sup>. The device was characterized by comparing its performance with reference data from synchrotron sources, and a parametric study investigated other effects that could affect the reliability of the spectral information.
Amorphous indium-tin-zinc oxide films deposited by magnetron sputtering with various reactive gases: Spatial distribution of thin film transistor performance (2015)

This work presents the spatial distribution of electrical characteristics of amorphous indium-tin-zinc oxide film (a-ITZO), and how they depend on the magnetron sputtering conditions using O2, H2O, and N2O as the reactive gases. Experimental results show that the electrical properties of the N2O incorporated a-ITZO film has a weak dependence on the deposition location, which cannot be explained by the bombardment effect of high energy particles, and may be attributed to the difference in the spatial distribution of both the amount and the activity of the reactive gas reaching the substrate surface. The measurement for the performance of a-ITZO thin film transistor (TFT) also suggests that the electrical performance and device uniformity of a-ITZO TFTs can be improved significantly by the N2O introduction into the deposition process, where the field mobility reach to 30.8 cm2 V–1 s–1, which is approximately two times higher than that of the amorphous indium-gallium-zinc oxide TFT.
Block copolymers as additives: a route to enhanced resist performance (1999)

The role of block copolymers as additives for improving resist performance in the area of 193 nm lithography is investigated in this study. We have demonstrated that specifically designed block copolymers when tailored to resist matrices to which they are added can profoundly enhance resist imaging performance. This improvement can be attributed to the ability of the block copolymers to modify surface and interfaces and to control photoacid generator distribution within the resist film. Ion beam techniques such as Rutherford Backscattering and Forward Recoil Spectrometry, used to analyze the distribution and segregation behavior of the photoacid generators and block copolymer additives, will also be described.
Nano-Structured Demineralized Human Dentin Matrix to Enhance Bone and Dental Repair and Regeneration (2019)

Demineralized dentin matrix (DDM), derived from human teeth, is an excellent scaffold material with exciting bioactive properties to enhance bone and dental tissue engineering efficacy. In this article, first the nano-structure and bioactive components of the dentin matrix were reviewed. Then the preparation methods of DDM and the resulting properties were discussed. Next, the efficacy of DDM as a bone substitute with in vitro and in vivo properties were analyzed. In addition, the applications of DDM in tooth regeneration with promising results were described, and the drawbacks and future research needs were also discussed. With the extraction of growth factors from DDM and the nano-structural properties of DDM, previous studies also broadened the use of DDM as a bioactive carrier for growth factor delivery. In addition, due to its excellent physical and biological properties, DDM was also investigated for incorporation into other biomaterials design and fabrication, yielding great enhancements in hard tissue regeneration efficacy.