gebhart/patrepeval huggingface dataset:
Streptococcus suis em funcionário de granja suinícola: primeiro isolamento no Brasil (2014)

Streptococcus suis represents a potential zoonosis risk in personnel working in close contact with swines. The purpose of this study was to evidence the human carrier status of S. suis in farm workers belonging to three different pig farms located in three different cities of the state of Sao Paulo, Brazil. Cotton swab samples were taken from tonsils of 28 workers. The S. suis-like strains were identified by polymerase chain reaction, confirmed by sequencing and serotyped by coagglutination technique. For the first time in Brazil, one farm worker was identified as a human carrier of S. suis.
A reference tissue atlas for the human kidney (2020)

A bstract Kidney Precision Medicine Project (KPMP) is building a spatially-specified human tissue atlas at the single-cell resolution with molecular details of the kidney in health and disease. Here, we describe the construction of an integrated reference tissue map of cells, pathways and genes using unaffected regions of nephrectomy tissues and undiseased human biopsies from 55 subjects. We use single-cell and -nucleus transcriptomics, subsegmental laser microdissection bulk transcriptomics and proteomics, near-single-cell proteomics, 3-D nondestructive and CODEX imaging, and spatial metabolomics data to hierarchically identify genes, pathways and cells. Integrated data from these different technologies coherently describe cell types/subtypes within different nephron segments and interstitium. These spatial profiles identify cell-level functional organization of the kidney tissue as indicative of their physiological functions and map different cell subtypes to genes, proteins, metabolites and pathways. Comparison of transcellular sodium reabsorption along the nephron to levels of mRNAs encoding the different sodium transporter genes indicate that mRNA levels are largely congruent with physiological activity.This reference atlas provides an initial framework for molecular classification of kidney disease when multiple molecular mechanisms underlie convergent clinical phenotypes.
Identification of a novel 45 kDa protein (JP-45) from rabbit sarcoplasmic-reticulum junctional-face membrane (2000)

Using a biochemical/immunological approach to analyse the protein constituents of skeletal-muscle junctional-face membrane (JFM), we identified a 45kDa protein. Its N-terminal amino acid was blocked, but the amino acid sequence obtained from several peptides after proteolytic treatment did not significantly match that of any protein present in the SwissProt and NCBI (National Center for Biotechnology Information) databases. We synthesized a peptide whose sequence matched that of one of the peptides obtained after CNBr cleavage of the 45kDa protein; the peptide was conjugated to a carrier and used to raise antibodies. The antiserum was used to study in more detail the biochemical characteristics of the novel 45kDa protein. Analysis of the proteins present in different subcellular membrane fractions show that the novel 45kDa polypeptide: (i) is an integral membrane constituent present both in neonatal and adult skeletal-muscle sarcoplasmic reticulum; (ii) is selectively localized in the JFM; (iii) is not present in microsomes obtained from rabbit heart, liver or kidney. Immunoprecitation with anti-(45kDa protein) antibody indicates that the 45kDa protein is part of a complex which can be phosphorylated in vitro by the catalytic subunit of protein kinase A.
From Two to One Per Day Calibration of Dexcom G4 Platinum by a Time-Varying Day-Specific Bayesian Prior (2016)

A Bayesian calibration algorithm employing a time-varying calibration function and suitable priors enables a reduction of the calibrations of DG4P sensor from two to one per day.
Quantization of Hall Conductance For Interacting Electrons on a Torus (2013)

We consider interacting, charged spins on a torus described by a gapped Hamiltonian with a unique groundstate and conserved local charge. Using quasi-adiabatic evolution of the groundstate around a flux-torus, we prove, without any averaging assumption, that the Hall conductance of the groundstate is quantized in integer multiples of e^2/h, up to exponentially small corrections in the linear size of the system. In addition, we discuss extensions to the fractional quantization case under an additional topological order assumption on the degenerate groundstate subspace.
Discovery of cross-tie walls at saw-tooth magnetic domain boundaries in permalloy films (1998)

Scanning electron microscopy with polarization analysis was used to image the surface magnetic domain structure of permalloy films (350 Å Ni83Fe17) in ultrahigh vacuum. These thin-film materials are used in a variety of magnetoresistive sensing applications, which depend on the state of the domains present in the film. In the demagnetized state of the films, saw-tooth domain boundaries separating two large approximately head-on domains were observed. At high magnification, cross-tie walls were seen with a periodic vortex structure along the straight edges of the saw-tooth domain boundaries.
A two layered approach for securing an object store network (2003)

Storage Area Networks (SAN) are based on direct interaction between clients and storage servers. This unmediated access exposes the storage server to network attacks, necessitating a verification, by the server, that the client requests conform with the system protection policy. Solutions today can only enforce access control at the granularity of entire storage servers. This is an outcome of the way storage servers abstract storage: an array of fixed size blocks. Providing access control at the granularity of blocks is infeasible there are too many active blocks in the server of entire servers is used. Object, stores (e.g, the NASD system) on the other hand provide means to address these issues. An object store control unit presents an abstraction of a dynamic collection of objects, each can be seen as a different array of blocks, thus providing the basis for Protection at the object level. In this paper we present a security model for the object store which leverages on existing security infrastructure. We give a simple generic mechanism capable of enforcing an arbitrary access control policy at object granularity. This mechanism is specifically designed to achieve low overhead by minimizing the cost of validating an operation along the critical data path, and lends itself for optimizations such as caching The key idea of the model is to separate the mechanisms for transport security from the one used for access control and to maximize the use standard security protocols when possible We utilize a standard industry protocol for authentication, integrity and privacy on the communication channel (IPSec for IP networks) anti fine a proprietary protocol for authorization on top of the secure communication layer.
An optimal design of crushing parameters of marine gas hydrate reservoirs in solid fluidization exploitation (2019)

To select reasonable excavating and crushing process parameters and nozzle structure parameters is one of the key factors to realize commercial excavation of marine natural gas hydrate (hereinafter “hydrate” for short) in solid fluidization exploitation. For analyzing the factors influencing jet crushing efficiency of hydrate in actual engineering, nozzle diameter, pump pressure and other parameters were simulated and analyzed in k–ε turbulence model based on the laboratory experiments and the field production test data at Liwan 3 Station in the northern South China Sea with a gas production rate of 120 thousand m3/d as the target of commercial hydrate exploitation. And the following research results were obtained. First, the relationship curves of nozzle diameter, pump pressure and displacement are determined when the critical jet speed for crushing hydrate is 24 m/s. Second, the crushing rate to satisfy the daily hydrate sediment excavation of commercial exploitation is 2.48 m3/min and its corresponding jet crushing diameter is 800 mm. Third, when the nozzle diameter is fixed, other parts in the process will be damaged if jet displacement and pump pressure are increased directly. In conclusion, these selected design parameters for commercially excavating and crushing marine non-diagenetic hydrate by means of solid fluidization are conducive to the optimal design of crushing parameters of hydrate in solid fluidization exploitation.
Deep Learning in Ultrasound Elastography Imaging (2020)

It is known that changes in the mechanical properties of tissues are associated with the onset and progression of certain diseases. Ultrasound elastography is a technique to characterize tissue stiffness using ultrasound imaging either by measuring tissue strain using quasi-static elastography or natural organ pulsation elastography, or by tracing a propagated shear wave induced by a source or a natural vibration using dynamic elastography. In recent years, deep learning has begun to emerge in ultrasound elastography research. In this review, several common deep learning frameworks in the computer vision community, such as multilayer perceptron, convolutional neural network, and recurrent neural network are described. Then, recent advances in ultrasound elastography using such deep learning techniques are revisited in terms of algorithm development and clinical diagnosis. Finally, the current challenges and future developments of deep learning in ultrasound elastography are prospected.
Let-7a Down-Regulation Plays a Role in Thyroid Neoplasias of Follicular Histotype Affecting Cell Adhesion and Migration through Its Ability to Target theFXYD5(Dysadherin) Gene (2012)

These results suggest a role of let-7a down-regulation in the development of thyroid neoplasias of the follicular histotype, likely regulating dysadherin protein expression levels.
Compact Rotman Lens with Size-Reduced Transition Structures between the Lens Body and the Connecting Lines (2013)

This paper introduces a new design for a Rotman lens that has been proposed to minimize its size and provide a suitable design for a compact beamforming system. The size reduction is realized by minimizing the length of the transition structures, which are positioned between the lens body and the connecting lines. The proposed structure is much shorter than a conventional transition structure, which is a tapered line in general. As a result, a 45% size reduction can be achieved by using the proposed transition structure, compared to a typical Rotman lens with linearly tapered lines. Therefore, the proposed Rotman lens will be suitable for compact beamforming systems.
Motor drive for a novel high-speed micro-milling spindle (2009)

This paper focuses on integration of a permanent magnet motor with active magnetic bearings for driving a high-speed micro-milling spindle. A new concept of supporting a short rotor with a slotless PM motor embedded by 5DOF bearings is conceived. In the concept, the bearings and motor functions remain independent. A 100 W, 200000 rpm motor compatible with magnetic bearings was designed and manufactured. An additional setup with aerostatic bearings was also constructed for testing of the motor.
Room temperature operation of a two dimensional photonic crystal defect-waveguide-laser with optical pump (2002)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text A. Sugitatsu and S. Noda, "Room temperature operation of a two dimensional photonic crystal defect-waveguide-laser with optical pump," in Integrated Photonics Research, A. Sawchuk, ed., Vol. 78 of OSA Trends in Optics and Photonics (Optica Publishing Group, 2002), paper IFF2. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Impact of Infliximab on weight regulation and lipid metabolism: Immuno-neutralization of TNF induces leptinemia in Crohn’s Disease (2003)

info:eu-repo/semantics/published
Nitration of TRPM2 as a Molecular Switch Induces Autophagy During Brain Pericyte Injury (2017)

A rapid induction in autophagy in human brain vascular pericytes, in the zinc oxide nanoparticles (ZnO-NP)-induced cell stress model, was paralleled with an increase in the expression of the TRPM2-S truncated isoform, which was abolished by treatment with a nitric oxide synthase inhibitor and a peroxynitrite scavenger. Furthermore, Y1485 in the C-terminus of the TRPM2 protein was identified as the tyrosine nitration substrate by mass spectrometry. Overexpression of the Y1485S TRPM2 mutant reduced LC3-II accumulation and pericyte injury induced by ZnO-NP. Consistently, LC3-II accumulation was reduced and pericytes were better preserved in intact brain microvessels of the TRPM2 knockout mice after ZnO-NP-induced vascular injury. Innovation and Conclusions: Our present study has revealed a novel mechanism of autophagy disturbance secondary to nitrosative stress-induced tyrosine nitration of TRPM2 during pericyte injury. Antioxid. Redox Signal. 27, 1297-1316.
LITERATURE REVIEW IN HOME CARE (2014)

ABSTRACT: Home Care replaces the traditional hospitalization or helps in the early discharge of a patient. The ob-jective of Home Care is to assign health professionals to patients at minimum cost, while satisfying various constraints and maintaining the quality of care. In this paper, we analyze the various types of problems that we have to face within this type of care structure. A systematic literature search was performed in a number of international databases. This review presents the existing problems treated in the home care context and also points out some problems which could not get much attention of the researchers.
Photocatalytic water gas shift using visible or simulated solar light for the efficient, room-temperature hydrogen generation (2013)

Gold nanoparticles supported on P25 TiO2 act as highly efficient photocatalysts for promoting the simultaneous H2O reduction to H2 and CO oxidation to CO2. This photocatalytic process can be performed using simulated solar light as well as light from a LED quasi monochromatic centred at 450 nm, indicating that not only UV but also visible light promotes the reaction. This novel photocatalytic reaction corresponds to the water gas shift which is an endothermic process that is currently carried out on a large industrial scale at temperatures about 350 °C. In contrast, the photocatalytic process is performed at ambient temperature with no other energy requirement than sunlight. Other related TiO2 and CeO2 photocatalysts containing noble metals (Pt or Pd) behave similarly, but with lower efficiency both in the UV and in the visible region than Au/TiO2.
A Concept and Implementation of Optimized Operations of Airport Surface Traffic (2010)

This paper presents a new concept of optimized surface operations at busy airports to improve the efficiency of taxi operations, as well as reduce environmental impacts. The suggested system architecture consists of the integration of two decoupled optimization algorithms. The Spot Release Planner provides sequence and timing advisories to tower controllers for releasing departure aircraft into the movement area to reduce taxi delay while achieving maximum throughput. The Runway Scheduler provides take-off sequence and arrival runway crossing sequence to the controllers to maximize the runway usage. The description of a prototype implementation of this integrated decision support tool for the airport control tower controllers is also provided. The prototype decision support tool was evaluated through a human-in-the-loop experiment, where both the Spot Release Planner and Runway Scheduler provided advisories to the Ground and Local Controllers. Initial results indicate the average number of stops made by each departure aircraft in the departure runway queue was reduced by more than half when the controllers were using the advisories, which resulted in reduced taxi times in the departure queue.
Premixed acidic calcium phosphate cement: Characterization of strength and microstructure (2010)

By using a premixed calcium phosphate cement (CPC), the handling properties of the cement are drastically improved, which is a challenge for traditional injectable CPCs. Previously premixed cements have been based on apatitic cements. In this article, acidic cement has been developed and evaluated. Monocalcium phosphate monohydrate and beta-tricalcium phosphate were mixed with glycerol to form a paste. As the paste does not contain water, no setting reaction starts and thus the working time is indefinite. Powder/liquid ratios (P/L) of 2.25, 3.5 and 4.75 were evaluated. Setting time (ST) and compressive strength (CS) were measured after 1 day, 1 week and 4 weeks in phosphate buffered saline (PBS) solution, and the corresponding microstructure was evaluated using electron microscopy and X-ray diffraction. The ST started when the cements were placed in PBS and ranged from 28 to 75 min, higher P/L gave a lower ST. Higher P/L also gave a higher CS, which ranged from 2 to 16 MPa. The microstructure mainly consisted of monetite, 1-5 microm in grain size. After 4 weeks in PBS, the strength increased. As acidic cements are resorbed faster in vivo, this cement should allow faster bone regeneration than apatitic cements. Premixed cements show a great handling benefit when compared with normal CPCs and can be formulated with similar ST and mechanical properties.
Associations of Microvascular Complications With the Risk of Cardiovascular Disease in Type 1 Diabetes (2021)

Advanced microvascular disease, especially moderate to severe albuminuria or eGFR <60 mL/min/1.73 m<sup>2</sup>, conveyed an increased risk of subsequent cardiovascular disease in the DCCT/EDIC cohort.
Chiral Mo−Binol Complexes:  Activity, Synthesis, and Structure. Efficient Enantioselective Six-Membered Ring Synthesis through Catalytic Metathesis (1999)

A new class of chiral Mo-based complexes 2a and 2b, bearing functionalized chiral binol ligands, is disclosed. Mo complex 2a promotes the asymmetric ring-closing metathesis (ARCM) of various dienes and trienes to afford six-membered carbo- and heterocycles efficiently and in high optical purity. The binol-based chiral Mo catalysts complement the previously reported biphen-based complexes, which are particularly effective in the enantioselective synthesis of five-membered rings by ARCM. Studies regarding catalytic kinetic resolutions and asymmetric desymmetrizations are described. It is possible to obtain optically pure products in high yield from catalytic reactions without the use of solvent (cf. eq 1). The structural attributes of these complexes are detailed on the basis of the data available from an X-ray structure and variable-temperature 1H NMR studies. The results of this investigation indicate the following: (i) The anti-Mo·THF complex exists as a mixture of diastereomers, whereas the syn isomer is formed stereoselectively. (ii) The anti-Mo isomers are likely more Lewis acidic.
Regulation of Peripheral Lymph Node Genesis by the Tumor Necrosis Factor Family Member Trance (2000)

Proper lymph node (LN) development requires tumor necrosis factor-related activation-induced cytokine (TRANCE) expression. Here we demonstrate that the defective LN development in TRANCE(-/)- mice correlates with a significant reduction in lymphotoxin (LT)alphabeta(+)alpha(4)beta(7)(+)CD45(+)CD4(+)CD3(-) cells and their failure to form clusters in rudimentary mesenteric LNs. Transgenic TRANCE overexpression in TRANCE(-/)- mice results in selective restoration of this cell population into clusters, and results in full LN development. Transgenic TRANCE-mediated restoration of LN development requires LTalphabeta expression on CD45(+) CD4(+)CD3(-) cells, as LNs could not be induced in LTalpha(-/)- mice. LTalpha(-/)- mice also showed defects in the fate of CD45(+)CD4(+)CD3(-) cells similar to TRANCE(-/)- mice. Thus, we propose that both TRANCE and LTalphabeta regulate the colonization and cluster formation by CD45(+) CD4(+)CD3(-) cells in developing LNs, the degree of which appears to correlate with the state of LN organogenesis.
Percutaneous MR Imaging–guided Transvascular Access of Mesenteric Venous System: Study in Swine Model (2006)

With use of only MR imaging guidance and an active MR imaging intravascular needle system, the authors were able to successfully puncture the SMV from the IVC with direct visualization of the needle and all retroperitoneal structures.
Recognizing cars in aerial imagery to improve orthophotos (2007)

The automatic creation of 3D models of urban spaces has become a very active field of research. This has been inspired by recent applications in the location-awareness on the Internet, as demonstrated in maps.live.com and similar websites. The level of automation in creating 3D city models has increased considerably, and has benefited from an increase in the redundancy of the source imagery, namely digital aerial photography. In this paper we argue that the next big step forward is to replace photographic texture by an interpretation of what the texture describes, and to achieve this fully automatically. One calls the result "semantic knowledge". For example we want to know that a certain part of the image is a car, a person, a building, a tree, a shrub, a window, a door, instead of just a collection of 3D points or triangles with a superimposed photographic texture. We investigate object recognition methods to make this next big step. We demonstrate an early result of using the on-line variant of a Boosting algorithm to indeed detect cars in aerial digital imagery to a satisfactory and useful level of completeness. And we show that we can use this semantic knowledge to produce improved orthophotos. We expect that also the 3D models will be improved by the knowledge of cars.
Designing Polymer Properties (2008)

This chapter contains sections titled: Polyolefins Levels and Scales of Polymer Structure and Modification Chain Structure: Chemistry, Interaction, Regularity, and Disturbance Chain Topology: SCB, LCB, and Special Structures Molecular Weight Distribution (MWD) Blends and Other Multiphase Structures Semi-crystalline Polymers: From Lattices to Superstructures Chain Structure and Crystallization Speed Lamellar Thickness and Modulus Nucleation and Polymorphism Flow-induced Structures and Processing Effects Multiphase Structures General Concepts of Impact Modification Multi-stage Copolymers (PP) Polymer Blends and Reactive Modification Compounds and (Nano) Composites Property Optimization in Processing Polymer Design: The Catalyst's Point of View Mechanisms and Kinetics: A “Tailors Toolbox” Activation, Initiation, Propagation: On your Marks, Get Set, …Go!! Chain Transfer Insertion Control Summary Case Study 1: Development of Commercially Relevant Single-Site iPP Catalysts Case Study 2: One Monomer, Many Microstructures Propylene Ethylene Case Study 3: FI Catalysts; From Lazy to Hyperactive, and Beyond Case Study 4: “Chain-shuttling” Immobilizing “Single-site” Olefin Polymerization Catalysts: The Basic Problems Reference
Polyhedral carbon nanoparticles at high pressures (2009)

The solid-phase transformations of polyhedral nanoparticles at a pressure of 8.0 GPa and various temperatures have been investigated by X-ray diffraction, small-angle X-ray scattering, and transmission electron microscopy. It has been found that the graphene layers of the inner cavities of polyhedral particles are transformed into onion-like structures at temperatures above ∼1000°C. This transformation gives rise to the formation of hybrid-type sp2 carbon nanoparticles, which combine the outer polyhedral shape with the quasispherical onion-like core. Polyhedral nanoparticles smaller than ∼40 nm are completely transformed into onion-like particles at 1600°C.