gebhart/patrepeval huggingface dataset:
An Introduction to Evolutionary Optimization for Microwave Engineering (2015)

This article overviews the fundamentals of evolutionary optimization as compared with conventional optimization techniques. We introduce evolutionary concepts through the simple genetic algorithm (SGA), particle swarm optimization (PSO), and present introductory examples demonstrating their use in microwave engineering.
Catalytic activity of native enzymes during capillary electrophoresis: an enzymic microreactor (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCatalytic activity of native enzymes during capillary electrophoresis: an enzymic microreactorLuis Z. Avila and George M. WhitesidesCite this: J. Org. Chem. 1993, 58, 20, 5508–5512Publication Date (Print):September 1, 1993Publication History Published online1 May 2002Published inissue 1 September 1993https://pubs.acs.org/doi/10.1021/jo00072a039https://doi.org/10.1021/jo00072a039research-articleACS PublicationsRequest reuse permissionsArticle Views221Altmetric-Citations76LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
o-Nitrobenzeneseleninic Acid (2001)

[56790-59-1] C6H5NO4Se (MW 234.08) InChI = 1S/C6H5NO4Se/c8-7(9)5-3-1-2-4-6(5)12(10)11/h1-4H,(H,10,11) InChIKey = LNJFIDXLARAFNQ-UHFFFAOYSA-N (catalyst with hydrogen peroxide for the epoxidation of alkenes,1, 2 the oxidation of sulfides,2 the Baeyer–Villiger oxidation of aromatic aldehydes and ketones,3 and the conversion of aldehydes to esters4 and nitriles5) Physical Data: mp 184–186 °C (dec). Solubility: slightly sol water; sol DMF. Preparative Methods: obtained from the oxidation of bis(2-nitrophenyl) diselenide with 30% Hydrogen Peroxide6 or concd Nitric Acid.7 Bis(2-nitrophenyl) diselenide is prepared by reaction of Lithium Diselenide with 2-nitrochlorobenzene8 or from the base hydrolysis of 2-nitrophenyl selenocyanate.1 Handling, Storage, and Precautions: both 2-nitrobenzeneseleninic acid and bis(2-nitrophenyl) diselenide are stable indefinitely at room temperature. Selenium compounds are potentially toxic and should be handled in a fume hood.
Isolation of the human plasma corticotrophin-releasing factor-binding protein (1989)

We report the purification of human corticotrophin-releasing factor-binding protein (hCRF-BP) using repeated affinity chromatography (with the aid of synthetic CRF immobilized on Sepharose 4B solid phase) followed by gel filtration. Presence of the binding protein was tracked throughout the procedure by its ability to inhibit binding of 125I-labelled hCRF to an hCRF antiserum; normal human plasma exhibits 80% inhibition in this system whereas sheep plasma, which does not contain an hCRF-BP, has no effect. Affinity cross-linking of 125I-labelled hCRF to the purified hCRF-BP was performed using disuccinimidyl suberate (1 mmol/l). SDS electrophoresis of the purified CRF cross-linked binding protein followed by radioautography resulted in one major band of Mr 37,000 which corresponded to our original molecular weight estimate based on the elution position of the binding protein on Sephacryl S-200. A 10(7)-fold purification of the hCRF-BP resulted in a preparation estimated to be 95% pure, with an overall yield of 5%.
自己組織化単分子膜を用いた有機不揮発性メモリの作製と閾値制御(センサ,デバイス,一般) (2010)

We examined 29 cases in which cerebral amyloid angiopathy (CAA) was detected among routine aged autopsies. Most cases with severe CAA had many amyloid-β (Aβ) plaques in the occipital cortex. Nonetheless, two cases had few Aβ plaques with many small vessels and capillaries with CAA. In the two cases, severe CAA was widely distributed, except in the frontal lobes. Aβ deposits in capillaries often showed the characteristic pattern of dysphoric amyloid angiopathy. A few naked plaques were present. Although Aβ plaques were sparse near small vessels with CAA, there were many Aβ plaques distant from small vessels with CAA. Some of the remaining plaques had a moth-eaten appearance. Based on Aβ-positive star-like appearance and results of double immunohistochemistry for glial fibrillary acidic protein and Aβ<sub>1-42</sub> , some astrocytes appeared to contain Aβ. Ionized calcium-binding adapter molecule 1 (Iba1)-positive microglia were scattered within the neuropil, with some present around small vessels with CAA. Iba1-positive microglia also seemed to phagocytose Aβ in several senile plaques by double immunostaining. Neurons and neurites identified with a monoclonal antibody against phosphorylated tau (clone AT8) were occasionally detected in sparse plaque areas, with AT8-identified dot-like structures present around capillaries with CAA. Accumulation of T lymphocytes was detected around vessels in the subarachnoid space in one case. The morphological changes detected in our two cases were similar to those of morphological markers of plaque clearance after Aβ immunotherapy. Nonetheless, our cases did not receive Aβ immunotherapy, but similar pathologies were observed. Overall, advanced CAA cases, including our two cases, may be examples of plaque clearance without Aβ immunotherapy. Further studies are needed to resolve the mechanism of Aβ plaque clearance using these cases.
Translation and Validation of the 8-Item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among Japanese Soft Contact Lens Wearers: the J-CLDEQ-8 (2019)

Abstract Purpose To translate and validate a Japanese version of the 8-item Contact Lens Dry Eye Questionnaire (CLDEQ-8) among a multicenter sample of Japanese-speaking soft contact lens (SCL) wearers in Japan. Methods The study comprised two phases, 1) forward and backward translation of the CLDEQ-8 into Japanese, 2) cross-sectional validation of Japanese CLDEQ-8 (J-CLDEQ-8) among Japanese spherical disposable SCL wearers (daily disposable, 2 week, or monthly disposable) against their Overall Opinion of SCLs, and 3) repeatability testing in a subset of subjects. Results 300 subjects (118 males and 182 females) completed the J-CLDEQ-8 and anchoring Gestalt SCL questions. The J-CLDEQ-8 had a strong significant linear relationship to Overall Opinion of SCLs and the Self-Assessment of Eye Dryness. The Gestalt Eye Sensitivity question did not translate well in Japanese and the relationship between it and the J-CLDEQ-8 was not linear. A cutoff score of Conclusions The J-CLDEQ-8 was capable of differentiating SCL wearers with different Overall Opinions of their SCLs, comparable to the original CLDEQ-8 in English.
Polysilicon photonic resonators for large-scale 3D integration of optical networks (2007)

We demonstrate optical microresonators in polycrystalline silicon with quality factors of 20,000. We also demonstrate polycrystalline resonators vertically coupled to crystalline silicon waveguides. Electrically active photonic structures fabricated in deposited polysilicon layers would enable the large-scale integration of photonics with current CMOS microelectronics.
New Targets in Cytometric Investigation of Acute Leukemia Selected From Gene Profiling Studies (2011)

Abstract Abstract 2536 BACKGROUND. Gene expression profiling (GEP) studies have identified previously unknown molecules that correlate with genotypes of acute leukemia (AL), prognosis and/or the malignant status itself. Although some of these molecules ignited enthusiasm upon their publication, confirmation on independent cohorts and using other reliable methods is needed. Using specific tools on gene or protein level will bring us closer to a conclusion as to what is the biologic importance of the molecules and whether each molecule is worth testing as potential new diagnostic or immunotherapeutic target. METHODS. We have selected genes with probable relevant correlation(s) with conditions listed above. Correlations were then tested using qPCR. Successfully tested genes were selected for the production of new monoclonal antibodies (mAbs), unless satisfactory mAbs were already available. The newly produced mAbs were tested together with those, which were commercially available, using cell lines and diagnostic bone marrow or peripheral blood specimens of children with AL; data were compared also to non-malignant tissues. Flow cytometry was applied both to entire cells and to a novel method of Size Exclusion Chromatography-Microsphere-based Affinity Proteomics (Size-MAP). RESULTS. Eighteen genes (CMTM2, AGPS, EFNB1, DBN1, Clic5a, MYO, LARGE, DDIT4L, TCEAL4, PCLO, ARHGEF4, HYA22, RAG1, Opal 1, Siva, EVI2b, CDC42EP3, and SH3BP5) were selected for testing on qPCR and/or cytometric level. Among them, correlations were confirmed in 9 molecules, excluded in 3 molecules, failed to conclude due to insufficient testing system (cell lines) in 2 molecules and pending in 1 molecule. In 3 molecules, we started mAb production without qPCR testing. The results were combined with those related to previously known mAbs. We have produced 56 novel mAb clones to 9 target molecules. Seventeen mAbs to 9 molecules were further tested using flow cytometry both on cells and by Size-MAP. Of these, mAb to drebrin (DBN1, Figure) was proven to correlate with TEL/AML1 positivity, while its correlation to better prognosis is waiting for a longer follow up.Figure:Two diagnostic specimens of leukemic cells that had negative (left) or high (right) expression of drebrin.Figure:. Two diagnostic specimens of leukemic cells that had negative (left) or high (right) expression of drebrin. Anti-drebrin and anti-OPAL-1 mAbs both showed reproducible signals using Size-MAP. The data were compared with the strong predictors of TEL/AML1 status (CD27 and CD44) that we showed previously. CONCLUSIONS. Some but not all of the molecules that were presented by GEP as promising targets can be detected by flow cytometry and their correlations with molecular genetics was confirmed. Grant support: National Program of Research II (NPVii, project 2B06064), GACR 301/10/1877, MZ CR NS10004-4, NS10480-3 and NS10473-3. Disclosures: No relevant conflicts of interest to declare.
ChemInform Abstract: Enantioselective Synthesis of Allylboronates Bearing a Tertiary or Quaternary B‐Substituted Stereogenic Carbon by NHC‐Cu‐Catalyzed Substitution Reactions. (2010)

Abstract Disubstituted as well as trisubstituted alkyl or aryl allylic carbonates are effective substrates.
Electromagnetic wave leakage absorption film using CNT spray (2021)

A CNT has a very low light density, about half that of aluminum, but its strength is about 20 times that of steel. Its current density resistance is more than 1000 times that of copper, and it also has higher thermal conductivity than copper. Although it is an excellent material that can be expected to be used in various fields, using it effectively proves to be a difficult task. We have succeeded in developing a flexible and stretchable CNT paint with the aim of applying this excellent material to DEA electrodes. This CNT paint can be easily applied to various materials by using a spray or other methods and since it can expand and contract, it can be applied to easily deformable materials such as polymers, wood, paper, and resin. It is possible to add the characteristics of CNTs to various materials. One of the characteristics of CNTs that has been attracting attention in recent years is the radio wave absorption effect. As the understanding of this process is expected to grow ever more important, the purpose of this paper is to verify the effect of radio wave absorption, one of the methods of utilizing CNTs, in the range from single to high double digit GHz bands.
Monitoring triplet state dynamics with fluorescence correlation spectroscopy: Bias and correction (2014)

A marker's dark triplet state is of great importance in fluorescence microscopy: It serves as a means to switch off fluorescent markers and is thus the enabling element for several super-resolution methods. On the other hand, intersystem-crossing to the electronic dark triplet state strongly reduces the fluorescence yield in conventional fluorescence microscopy. The ability to determine the kinetic parameters of transitions into the triplet state is thus of great importance and because fluorescence correlation spectroscopy (FCS) can be applied without disturbing the system under study, it is one of the preferred methods to do so. However, conventional FCS observations of triplet dynamics suffer from bias due to the spatially inhomogeneous irradiance profile of the excitation laser. Herein, we present a novel method to correct this bias and verify it by analyzing both Monte Carlo simulated and experimental data of the organic dye Rhodamine 110 in aqueous solution for both continuous-wave and pulsed excitation. Importantly, our approach can be readily generalized to most other FCS experiments that determine intensity dependent kinetic parameters.
Rate Dependent Multi-Mechanism Discharge of Ag0.50VOPO4·1.8H2o: Insights from in-Situ Energy Dispersive X-Ray Diffraction (2017)

Ag 0. 50 VOPO 4 ·1.8H 2 O (silver vanadium phosphate, SVOP) demonstrates a counterintuitive higher initial loaded voltage under higher discharge current. Energy dispersive X-ray diffraction (EDXRD) from synchrotron radiation was used to create tomographic profiles of thick cathodes at various depths of discharge for two discharge rates. SVOP displays two reduction mechanisms, reduction of a vanadium center accompanied by lithiation of the structure, or reduction-displacement of a silver cation to form silver metal. In-situ EDXRD provides the opportunity to observe spatially resolved changes to the parent SVOP crystal and formation of Ag 0 during reduction. Discharge rate can influence the preferred initial reaction either V 5+ reduction or reduction of Ag + with formation of conductive Ag 0 . Discharge rate also affects the spatial location of reduction products. This study highlights the importance of mesoscopic analysis and illuminates the roles of electronic and ionic conductivity limitations within a cathode and how they impact the course of reduction processes and loaded voltage.
Generation and reactivities of organocerium reagents (1982)

Organocerium reagents, prepared in situ by the treatment of organolithium compounds with cerium(III) iodide, exhibit characteristic reactivities toward ketones; at –65 °C, nucleophilic additions give the corresponding tertiary alcohols in excellent yields, while, at 0 °C to ca. room temperature, reductive coupling and/or reduction of the ketones prevail.
The new amino acid .beta.-carboxyaspartic acid (asa). Laboratory synthesis and identification in the ribosomal proteins of E. coli (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe new amino acid .beta.-carboxyaspartic acid (asa). Laboratory synthesis and identification in the ribosomal proteins of E. coliM. Robert Christy, Robert M. Barkley, Tad H. Koch, John J. Van Buskirk, and Wolff M. KirschCite this: J. Am. Chem. Soc. 1981, 103, 13, 3935–3937Publication Date (Print):July 1, 1981Publication History Published online1 May 2002Published inissue 1 July 1981https://pubs.acs.org/doi/10.1021/ja00403a060https://doi.org/10.1021/ja00403a060research-articleACS PublicationsRequest reuse permissionsArticle Views140Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Transformation electromagnetics enabled lens design with surrogate-assisted global optimization (2017)

A gradient index lens is designed by utilizing quasi-conformal transformation electromagnetics (QCTEM) to define the index distribution in a rotationally symmetric lens. The smooth and continuous nature of QCTEM is investigated and an analytical surrogate model is trained to replace the computationally intensive QCTEM procedure and ray trace simulations. The surrogate model is then incorporated into an optimization strategy which is able to converge to an optimal design in substantially fewer function evaluations than a traditional global optimization scheme.
Heterogeneous Integration of GaN and BCD Technologies and Its Applications to High Conversion-Ratio DC–DC Boost Converter IC (2018)

This letter presents a novel technology for the integration of gallium nitride (GaN) power devices with silicon control circuits. It comprises stacked GaN power transistors and bipolar-CMOS-double-diffused metal-oxide-semiconductor (DMOS) (BCD) circuits. It leverages on both advantages of the high-voltage low-loss GaN devices and the high-integration BCD circuits. Using conventional manufacturing, packaging, and assembly techniques and equipment, the proposed technology is technology transferrable and applicable for commercial power electronic applications. To validate the concept, a 3.3-70 V dc-dc boost converter is designed, implemented, and verified experimentally. It features a conversion efficiency of 70.3%, output power of 1.68 W, and compact size of 0.32 × 0.18 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
Long Term Viability of HFO-1234yf in Stationary Refrigeration Systems - Multi-Year Evaluation of Refrigerant, Lubricant, and Compressor Performance in a Domestic Freezer (2014)

In recent years, HFO-1234yf has been introduced as a low global warming potential (GWP) replacement for HFC-134a in a variety of refrigeration and air conditioning applications both as a pure fluid (mildly flammable) and in refrigerant blends (both mildly flammable and non-flammable). A large and growing body of work on HFO-1234yf exists for mobile air conditioning, however recently interest in the use of R-1234yf in stationary refrigeration applications is growing. This paper will report the results of the longest continuous test to date (> 4 years) of a commercial stationary system operating on R-1234yf refrigerant. The test was initiated in 2009 in a 4ft reach in chest freezer by recovering the R-134a and replacing with R-1234yf. Since that time the system has operated normally and energy usage and operating data has been continuously collected. Recently, the freezer was shut down, refrigerant and oil samples collected for chemical and physical analyses and the compressor removed for a tear down inspection. Operational and energy performance data for the system over the duration of the extended test period will be presented and compared to baseline operation on R-134a. Results of the system performance data as well as the chemical stability measurements of R-1234yf and POE oil, along with the compressor tear down metrology will be used to validate the long term viability of this new class of low GWP refrigerants (HFO’s) and R-1234yf in particular.
OUTCOME AFTER O RIF OF CAPITELLUM AND TROCHLEA FRACTURES (2008)

The functional outcomes of twenty-eight patients with capitellum and trochlea fractures treated with open reduction and internal fixation were evaluated at a mean follow-up of fifty-five ± thirty-three months. Patients were independently evaluated by a series of questionnaires, radiographs, physical examination and strength testing. Patients with simple fractures did better than those with complicated fractures. The average DASH score was 19/100 and the average ROM was 20 – 130°. Two fractures did not unite and required conversion to total elbow arthroplasty. A classification system is proposed based on fracture patterns, surgical technique and clinical outcomes. Capitellum and trochlea fractures are uncommon fractures of the distal humerus. There is limited information about the functional outcome of patients managed with open reduction and internal fixation. The functional outcome of twenty-eight patients (average age: forty-three ± thirteen years [range, twenty – seventy-one]) who were treated with open reduction and internal fixation for capitellum and trochlea fractures was evaluated at a mean follow-up of fifty-five ± thirty-three months (range, fourteen – one hundred and twenty-one). Patient outcomes were assessed by physical examination, radiographs, range of motion measurements, strength testing and self reported questionnaires (DASH, SF-36 ASES and PREE elbow scales). There were eleven fractures involving the capitellum, four involving the capitellum and trochlea as one piece and thirteen in which the capitellum and trochlea were separate fragments. These fractures were further defined by the presence or absence of posterior comminution. Fourteen had isolated fractures and fourteen were associated with other elbow, forearm or wrist injuries. Patients with complicated fractures required more extensive surgery, had more complications resulting in secondary procedures and had poorer outcomes compared to those with simple fractures. The average DASH score (19/100), quality of life scores (SF-36: Physical=46, Mental=49) and the average ROM (20 – 130°) suggest favorable patient outcomes overall. Patients with simple fractures had better results than those with more complicated fractures. A fracture classification system based on fracture patterns, surgical technique and clinical outcomes is proposed.
Attribute-Based Signatures for Unbounded Languages from Standard Assumptions. (2018)

Attribute-based signature (ABS) schemes are advanced signature schemes that simultaneously provide fine-grained authentication while protecting privacy of the signer. Previously known expressive ABS schemes support either the class of deterministic finite automata and circuits from standard assumptions or Turing machines from the existence of indistinguishability obfuscations.
ChemInform Abstract: Differential Binding Energy: A Detailed Evaluation of the Influence of Hydrogen‐Bonding and Hydrophobic Groups on the Inhibition of Thermolysin by Phosphorus‐Containing Inhibitors. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.