gebhart/patrepeval huggingface dataset:
Modeling and Discovery of Data Providing Services (2008)

Abstract Web Services providing access to datasources with structured data have an important place in the SOA. In this paper we focus on modeling and discovery of generic data providing services (DPS), with the goal of making data providing services available for interactions with service requesters in contexts such as service composition and mediation. In our model RDF Views are used to represent the content provided by the DPS. A characterization of match between description of DPS as RDF Views and the OWL-S service request is specified, based on which we developed a flexible matchmaking algorithm for discovery of data providing services. Finally, we propose a realization of the DPS using a SOAP version of the SPARQL protocol and a dynamic configuration interface allowing easy interactions of service requesters with data providing services.
EXHANCE-3: a cohort study of the exhalation delivery system with fluticasone for chronic sinusitis with or without nasal polyps (2019)

705 comparatively refractory subjects were enrolled, 603 CRSsNP and 102 CRSwNP [moderate-to-severely symptomatic; baseline SNOT-22 ~43, high rates of prior INS use (92.3%) and/or prior surgery (27.5%)]. More than 90% reported improvement on treatment by PGIC. SNOT-22 scores improved substantially and similarly in patients with NP (-23.7) and without NP (-24.4). Among patients with baseline Lund-Kennedy edema scores >0, 33.3% (CRSwNP) and 54.8% (CRSsNP) had complete resolution of edema. In CRSwNP patients, 48% had polyp elimination in ?1 nostril, 63% had ?1-point improvement in polyp grade, mean bilateral polyp grade decreased from 2.9 to 1.6, and study-defined surgical eligibility decreased. EDS-FLU was generally well tolerated, with a safety profile similar to conventional INS sprays when used to treat CRS CONCLUSION: EDS-FLU 372 #181;g BID in the treatment of CRS with or without polyps was safe, well-tolerated, and produced substantial improvement across a broad range of both objective and subjective measures.
Deformable registration with spatially varying degrees of freedom constraints (2008)

Intra-subject deformable registration applications, such as longitudinal analysis and multi-modal imaging, use a high degree freedom deformation to accurately align soft tissue. However, smoothness constraints applied to the deformation and insufficient degrees of freedom in the deformation may distort the more rigid tissue types such as bone. In this paper, we present a technique that aligns rigid structures using rigid constraints while aligning soft tissue with a high degree of freedom deformation.
Formation of Perfluoropolyether Coatings by the Rapid Expansion of Supercritical Solutions (RESS) Process. Part 2:  Numerical Modeling (2001)

The rapid expansion of supercritical solutions (RESS) process is a promising method for the production of ultrafine powders and aerosols of narrow size distribution for coatings and other applications. In this article, part 2 of a two-part study, the nucleation and subsequent growth of 2500 Mw perfluoropolyether diamide (PFD) from supercritical carbon dioxide (CO2) by expansion through a small-diameter nozzle is modeled in a three-stage, multidimensional fashion. The stages include a hydrodynamic solution, solvent−solute phase equilibria analyses, and an aerosol transport model. The hydrodynamics model successfully captures the vapor−liquid transition that occurs as carbon dioxide is expanded to ambient conditions. Cloud-point pressures and equilibrium compositions of the separated solvent−solute system are determined and are used in a multidimensional aerosol transport model. This model incorporates various mechanisms influencing droplet growth. Parametric studies are conducted to investigate the influences of the interfacial tension, the equilibrium addition of carbon dioxide, and the diffusion coefficient on the predicted droplet diameter. Turbulent coagulation in the ambient region downstream of the expansion nozzle is found to be the dominant mechanism responsible for the production of micron-sized droplets observed in companion experiments.
Satisfaction with a Segesterone Acetate and Ethinyl Estradiol Contraceptive Vaginal System Among Recent Oral Contraceptive or Hormonal Contraceptive Vaginal Ring Users (2023)

<b><i>Background:</i></b> We evaluated satisfaction with use of a segesterone acetate and ethinyl estradiol (0.15/0.013 mg) contraceptive vaginal system (CVS) among women who had recently used a monthly contraceptive vaginal ring or contraceptive pills. The CVS is a ring-shaped device used in a 21-days-in/7-days-out regimen for 13 cycles. <b><i>Materials and Methods:</i></b> We analyzed <i>post hoc</i> satisfaction responses at cycle 3 and end of study (EOS) from a subset of participants with documented recent use of the monthly ring or daily pills before enrollment in a multinational, phase 3, 13-cycle trial evaluating the CVS. EOS included results from participants who had completed ≥10 cycles. Results were summarized descriptively. <b><i>Results:</i></b> We identified 128 recent ring and 219 recent pill users at cycle 3 (of 1033 survey participants), and 92 and 148, respectively, at EOS (of 622 survey participants); overall satisfaction with CVS use was high (≥90%). At EOS, most ring (89%) and pill (97%) users liked the CVS as much/better than any previous method. The two most-liked CVS features included ease of use and 1-year duration; the two most disliked features included ring insertion and feeling it coming out. At EOS, ≥88% of both groups reported no concern about using the same CVS for a year, and most (>80%) had recommended it to friends or family members. <b><i>Conclusion:</i></b> The CVS clinical trial participants who were recent ring/pill users reported high satisfaction and liked it as much/better than any previously used contraceptive; the CVS may be a good contraceptive option for switchers. Clinical trial registration NCT00263341.
Bringing Solid-State Magnetocaloric Cooling to the Market: A Commercialization Plan (2017)

Air conditioning has become a staple in American life, bringing improved health, productivity, and comfort to 93% of single-family homes as of 2015, compared to only 76% in 1990. This rise in demand has contributed to the 2.51 quads (12.5%) of total annual energy consumption in residential buildings attributable to space cooling (U.S. Energy Information Administration 2017). Accompanying this upward trend in space cooling has been increased refrigerant use, which has historically contributed to ozone depletion, global warming, or both. The Oak Ridge National Laboratory – along with German-based partner Vacuumschmelze GmbH & Co. KG – is working to reduce energy consumption and refrigerant use through the development of a next-generation, solid-state magnetocaloric cooling system. The purpose of this study is to investigate market potential of these systems in the United States, including information on the industry landscape, market share and unit shipment projections, optimal price points, and barriers to market entry.
ChemInform Abstract: Photoconductive Smectic Liquid Crystals and Their Application to Opto‐Electronic Devices (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
EXTREMAL DEPENDENCE: INTERNET TRAFFIC APPLICATIONS (2005)

ABSTRACT For bivariate heavy tailed data, the extremes may carry distinctive dependence information not seen from moderate values. For example, a large value in one component may help cause a large value in the other. This is the idea behind the notion of extremal dependence. We discuss ways to detect and measure extremal dependence. We apply the techniques discussed to internet data and conclude that for files transferred, file size and throughput (the inferred rate at which the file is transferred) exhibit extremal independence.
Supporting adaptive multimedia with the wandering network model (2003)

The wandering network is a new type of communications architecture defined by: 1) flexible, multi-modal specialization of network nodes as virtual subnetworks; 2) mobility and virtualization of the net functions in hardware and software; and 3) self-organization as multi-feedback-based topology on-demand. Network elements can contain several exchangeable modules capable of executing diverse network functions in parallel. They can be invoked, transported to or generated in the nodes upon delivery of mobile code containing programs about the node's behaviour.
Cooperative nutrient accumulation sustains growth of mammalian cells (2015)

The coordination of metabolic processes to allow increased nutrient uptake and utilization for macromolecular synthesis is central for cell growth. Although studies of bulk cell populations have revealed important metabolic and signaling requirements that impact cell growth on long time scales, whether the same regulation influences short-term cell growth remains an open question. Here we investigate cell growth by monitoring mass accumulation of mammalian cells while rapidly depleting particular nutrients. Within minutes following the depletion of glucose or glutamine, we observe a growth reduction that is larger than the mass accumulation rate of the nutrient. This indicates that if one particular nutrient is depleted, the cell rapidly adjusts the amount that other nutrients are accumulated, which is consistent with cooperative nutrient accumulation. Population measurements of nutrient sensing pathways involving mTOR, AKT, ERK, PKA, MST1, or AMPK, or pro-survival pathways involving autophagy suggest that they do not mediate this growth reduction. Furthermore, the protein synthesis rate does not change proportionally to the mass accumulation rate over these time scales, suggesting that intracellular metabolic pools buffer the growth response. Our findings demonstrate that cell growth can be regulated over much shorter time scales than previously appreciated.
Application and generalizability of U-Net segmentation of immune cells in inflamed tissue (2021)

Several disease states, including cancer and autoimmunity, are characterized by the infiltration of large populations of immune cells into organ tissue. The degree and composition of these invading cells have been correlated with patient outcomes, suggesting that the intercellular interactions occurring in inflamed tissue play a role in pathology. Immunofluorescence staining paired with confocal microscopy produce detailed visualizations of these interactions. Applying computer vision and machine learning methods to the resulting images allows for robust quantification of immune infiltrates. We are developing an analytical pipeline to assess the immune environments of two distinct disease states: lupus nephritis and triple-negative breast cancer (TNBC). Biopsies of inflamed kidney tissue (lupus) and tumors (TNBC) were stained and imaged for panels of 20 markers using a strip-reprobe technique. This set of markers interrogates populations of T-cells, B-cells, and antigen presenting cells. To detect T cells, we first trained a U-Net to segment CD3+CD4+ T-cells in images of lupus biopsies and achieved an object-level precision of 0.855 and recall of 0.607 on an independent test set. We then evaluated the generalizability of this network to CD3+CD8+ T cells in lupus nephritis and CD3+CD4+ T cells in TNBC, and the extent to which fine-tuning the network improved performance for these cell types. We found that recall increased moderately with finetuning, while precision did not. Further work will focus on developing robust methods of segmenting a larger variety of T cell markers in both tissue contexts with high fidelity.
Low Loss SOI Waveguides and MMIs at the MIR Wavelength of $2~\mu$ m (2016)

In this letter, we demonstrate high-performance waveguides and MMIs on an SOI platform at the fixed wavelength of 2 μm. The propagation loss demonstrated by the waveguides and the insertion loss of the MMIs are as low as 1 dB/cm and 0.29 dB, respectively, with TE polarization. To the best of our knowledge, this is the lowest loss for Si rib waveguides reported at a wavelength of 2 μm.
Joint Optimization of User Association and Inter-Cell Interference Coordination for Proportional Fair-Based System Throughput Maximization in Heterogeneous Cellular Networks (2017)

This paper proposes a proportional fair-based joint optimization method for user association and the bandwidth ratio of protected radio resources exclusively used by pico base stations (BSs) for inter-cell interference coordination (ICIC) in heterogeneous networks where low transmission-power pico BSs overlay a high transmission-power macro BS. The proposed method employs an iterative algorithm, in which the user association process for a given bandwidth ratio of protected radio resources and the bandwidth ratio control of protected radio resources for a given user association are applied alternately and repeatedly up to convergence. For user association, we use our previously reported decentralized iterative user association method based on the feedback information of each individual user assisted by a small amount of broadcast information from the respective BSs. Based on numerical results, we show that the proposed method adaptively achieves optimal user association and bandwidth ratio control of protected radio resources, which maximizes the geometric mean user throughput within the macrocell coverage area. The system throughput of the proposed method is compared to that for conventional approaches to show the performance gain.
Cytomegalovirus Infection Incidence and Risk Factors Across Diverse Hematopoietic Cell Transplantation Platforms Using a Standardized Monitoring and Treatment Approach: A Comprehensive Evaluation from a Single Institution (2018)

Human cytomegalovirus (CMV) infection and disease remains a significant cause of morbidity and mortality for hematopoietic cell transplantation (HCT) recipients. Disruption of or weak reconstitution of virus-specific cellular immune function, such as with certain HCT approaches, poses significant risk for CMV-related complications. The incidence of and risk factors for CMV infection and the nature of CMV disease were evaluated retrospectively among 356 consecutive HCT recipients transplanted at the National Institutes of Health using all graft sources, including bone marrow, peripheral blood stem cell (PBSC), and umbilical cord blood (UCB), and a range of in vivo and ex vivo approaches for graft-versus-host disease (GVHD) prophylaxis. The cumulative incidence of CMV infection was higher for CMV-seropositive recipients at 33%, regardless of donor CMV serostatus. Patients transplanted with CMV-seropositive donors had a significantly shorter duration of antiviral therapy. Among graft sources UCB was associated with the highest cumulative incidence of CMV infection at 65% and significantly longer treatment duration at a median of 36days, whereas PBSC HCT was associated with the lowest incidence at 26% and the shortest CMV treatment duration at a median of 21days. There were significant differences in the cumulative incidence of CMV infection by T cell manipulation strategy when systemic steroids were included as a risk-modifying event. Over one-third of CMV infections occurred in the setting of systemic steroid administration. CMV disease occurred in 5% of HCT recipients, with 70% of cases in the setting of treatment for GVHD. Although factors related to serostatus, graft source, and GVHD prophylaxis were associated with varied CMV infection incidence, unplanned post-HCT corticosteroid therapy contributed greatly to the incidence of both CMV infection and disease across HCT approaches, highlighting this post-HCT intervention as a key time to potentially tailor the approach to monitoring, preemptive therapy, and even prophylaxis.
Online Asynchronous Coded Caching (2019)

Coded caching is a technique for reducing peak data rate in content delivery systems that employ caching. The original formulation of the coded caching problem assumes that the file requests from the users are synchronous, i.e., they arrive at the same time. In this work, we consider the asynchronous setting where the file requests are revealed to the server in an online fashion. We propose a novel online algorithm for this problem building on our prior work for the offline setting (where the server knows the request arrival times and deadlines in advance). Our simulation results demonstrate that our proposed online algorithm allows for a natural tradeoff between the feasibility of the schedule and the rate gains of coded caching.
Zamknięcie perforacji wolnej ściany lewej komory zatyczką Amplatzer-Muscular VSD Occluder pod kontrolą wewnątrzsercowego badania echokardiograficznego i wideotorakoskopii (2005)

Wstep : W czasie zabiegow kardiologii interwencyjnej konieczne jest niekiedy uzycie koszulek
o duzej średnicy. Celem niniejszej pracy byla ocena monitorowania przezskornego zamkniecia
perforacji wolnej ściany lewej komory zatyczką Muscular VSDO z uzyciem wewnątrzsercowego
badania echokardiograficznego sondą elektroniczną (ICE AcuNav), sondą mechaniczną (ICE-IVUS, Boston Scientific) oraz z zastosowaniem wideotorakoskopii i badania angiograficznego. 
Material i metody : Zabiegi przeprowadzono u 8 świn pod kontrolą wewnątrzsercowego
badania echokardiograficznego oraz wideotorakoskopii i angiografii w Centre Hospitalier
Universitaire Vaudois CHUV w Lozannie. 
Wyniki : U wszystkich świn zamknieto otwor w ścianie lewej komory zatyczką Muscular VSDO. 
Wnioski : Badanie ICE-AcuNav, wykonane lącznie z badaniem angiograficznym, pozwala
na zadowalające monitorowanie interwencyjnego zabiegu kardiologicznego zamykania otworu
w ścianie lewej komory z uzyciem zatyczki Muscular VSDO. W zabiegach przeprowadzonych
calkowicie przezskornie kontrola torakoskopowa pozwolila na śledzenie naciecia worka osierdziowego,
wybranie miejsca naklucia ściany serca oraz monitorowanie otwarcia dysku dystalnego
zatyczki Muscular VSDO i krwawienia.
Design of a Connected-Object using LoRa technology for students’ life improvement (2021)

International audience
Photonic band gap effect and structural color from silver nanoparticle gelatin emulsion (2005)

We have fabricated planar structures of silver nanoparticles in monochromatic gelatin emulsion with a continuous spacing ranging from 0.15-0.40 micron using a two-beam interference of a single laser source. Our planar holograms display a colorful "rainbow" pattern and photonic bandgaps covering the visible and IR ranges. We model the planar silver nanoparticle-gelatin composite system using an effective medium approach and good agreement is obtained between theory and experiment.
Cardiac Troponin I: Ultrasensitive Detection Using Faradaic Electrochemical Impedance (2018)

An electrochemical biosensor for the detection of cardiac troponin I, cTnI, an important cardiac biomarker, is described. A combination of a novel monoclonal antibody, mAb20B3, and a novel Ir(III)-based metal complex was used for detection using faradaic electrochemical impedance spectroscopy. A limit of detection of 10 ag/mL was achieved, which is significantly lower than established assays. The ability to detect these ultralow concentrations enables rapid and early stage detection of cardiac events and opens up the possibility of developing a point-of-care device.
A fully-telescoped, aqueous, auxiliary-mediated asymmetric transformation (2005)

A fully-telescoped, aqueous, auxiliary-mediated Diels-Alder cycloaddition in moderate selectivity is reported. The auxiliary is prepared from L-asparagine and trimethylacetaldehyde, and coupled without isolation to the acryloyl substrate. Direct addition of cyclopentadiene generates the cycloadduct, which is cleaved from the heterocycle upon mild treatment with acid and heat. A significantly reduced selectivity is observed relative to the two-pot synthesis in which the acrylamide is precipitated and washed prior to the cycloaddition. Vacuum-assisted removal of the acrylic acid contaminant prior to the cycloaddition substantially remedies the reduced selectivities achieved in the one-pot transformation relative to the two-step sequence. Four chemical transformations, not including acid/base reactions, are accomplished in this onepot synthesis.
Stability metric based routing protocol for low-power and lossy networks (2014)

To design a routing protocol for applications over low-power and lossy networks (LLNs), the IETF ROLL Working Group standardized the IPv6 Routing Protocol for LLNs (RPL), which organizes nodes in a LLN into a tree-like topology called Destination Oriented Directed Acyclic Graph (DODAG). RPL shows good scalability and fast network setup. However, it may suffer from severe unreliability due to the selection of suboptimal routes with low quality links. To optimize the reliability of RPL routes, this paper proposes a stability metric based routing protocol named sRPL for reliable routing and data collection in LLNs. We introduce a new routing metric for RPL called stability index (SI), which exploits stability characteristics of RPL nodes to select more stable routes. In addition, we present a passive and lightweight network layer technique to measure the bi-directional expected transmission count (ETX) for wireless links in LLNs. As a use case of SI, we combine SI metric with ETX metric to make routing decisions. Simulation results show that sRPL can improve packet delivery rate of RPL routing protocol by 20%.
Dynamic PET Imaging Reveals Heterogeneity of Skeletal Muscle Insulin Resistance (2013)

Lower glucose transport rates are the major feature underlying IR preceding type 2 diabetes, although substantial heterogeneity in insulin action across muscle types highlight the complexity of skeletal muscle IR.
ChemInform Abstract: INTRAMOLEKULARE OXIDATIVE PHENOL‐KUPPLUNG 2. MITT. SYNTH. VON (+‐)‐MARITIDIN NACH BIOGENETISCHEM SCHEMA (1970)

Abstract Die Norbelladin‐Verbindung (Ia) wird in ihr Trifluoracetyl‐Derivat (Ib) (96% Ausbeute) übergeführt, das durch intramolekulare oxidative para‐para‐Phenol‐Kupplung zu dem Dienon (II) (24%) umgesetzt wird.