gebhart/patrepeval huggingface dataset:
Untersuchung des Einflusses von Regelungsstrategien auf den Heizwärmebedarf und die operative Raumtemperatur bei unterschiedlichen Gebäudestandards (2011)

Hofer Richard: Examination of the effect of the control strategy on the heating demand and the operative temperature with different building standards The present master thesis was started within the project "ThinkHome" on the "Institute of Computer Aided Automation" which is part of the TU Vienna."ThinkHome" is an advanced control of all building services (Heating, Ventilation, etc.) which makes it possible to execute user defined strategies but also learns from the users' behavior.The compiled simulation serves as a testing environment for first experiments of the intelligent control system.The model calculates heat flows for a building with two zones taking the influence of the climate, the user behavior, the geometry of the building and the material parameters into account.A calculation of the heating demand and temperature curves is therefore possible.All modules, which are needed to execute these calculations, are described in detail: structural elements, systems and the interaction with the user.Comparisons are made between the own simulation and HAMBASE.These should point out differences and describe the behavior of both simulation environments.In the end two heating strategies are tested with the model and the results are compared with a static calculation.Version "a" describes a continuous heating system, which does not take the user occupancy into account.In Version "b" a typical ON/OFF control strategy is used, which does not supply heat when the user is absent and which tries to reach the comfort temperature when the user is present. Inhaltsverzeichnis I
Screening and construction of probiotic strains with enhanced protective properties against intestinal disorders (2004)

Within the scope of the DEPROHEALTH project, a range of wild-type strains of Lactobacillus were analysed for their ability to interact with the host immune system. While the studied isolates interacted in a strain-specific way with immune cells, they seemed to have little and non-discriminative effect on epithelial cells. However, they were shown to facilitate the cross-talk between intestinal and immune cells. Studies conducted in mouse colitis models confirmed that specific strains possess higher intrinsic anti-inflammatory properties. Two of these were further engineered to produce murine IL10 and are presently being evaluated for their protective effect in a TNBS colitis model. Cell wall mutants of Lactobacillus plantarum NCIMB8826 were analysed for their phenotypic traits, immune modulatory ability and capacity to act as live carriers. This led to the identification of mutants with increased anti-inflammatory or antigen delivery properties. Substantial work was invested in attempts to increase the immune response induced by recombinant lactobacilli producing Helicobacter or rotavirus antigens. In the course of these experiments, new methods to evaluate the load of Helicobacter in infected mice were developed. Novel targeting signals for cell surface presentation of therapeutic molecules were also identified. Finally, a safe biologically contained lactococcal strain secreting human IL10 was constructed, thus opening the way to a first clinical trial in patients suffering from inflammatory bowel disease (IBD).
Bend sensitive wavelength filtering in concentric core solid photonic bandgap fibre (2008)

Bend sensitive wavelength filtering property in a concentric core solid photonic bandgap fibre is resented. The property is realised by not only the bandgap effect but mode coupling between the core mode and ring modes.
Host factors in breast cancer recurrence. (1992)

Article Tools Article Tools OPTIONS & TOOLS Export Citation Track Citation Add To Favorites Rights & Permissions COMPANION ARTICLES No companion articles ARTICLE CITATION DOI: 10.1200/JCO.1992.10.11.1817 Journal of Clinical Oncology - published online before print September 21, 2016 PMID: 1403063 Host factors in breast cancer recurrence. H W DaniellxH W DaniellSearch for articles by this author https://doi.org/10.1200/JCO.1992.10.11.1817 PDF "Host factors in breast cancer recurrence.." Journal of Clinical Oncology, 10(11), pp. 1817–1819© 1992 by American Society of Clinical Oncology
Enhanced Guest@MOF Interaction via Stepwise Thermal Annealing: TCNQ@Cu3(BTC)2 (2021)

Confinement of guest molecules in porous materials such as metal–organic frameworks (MOFs) promises to deliver emergent properties separate from those of the individual components. Understanding the confinement mechanism is therefore important for the development of new synthesis routes that adjust MOF properties for specific applications. In this work, we developed a new synthetic method to confine guest molecules into MOF pores through a stepwise thermal annealing process, wherein the confinement of 7,7,8,8-tetracyanoquinodimethane (TCNQ) guest molecules into the Cu3(BTC)2 (BTC = benzene-1,3,5-tricarboxylic acid) MOF host is used as an example of how novel materials can be created with new physical properties. The stepwise thermal annealing process includes (1) an activation process of the pristine Cu3(BTC)2 MOF to maximize the TCNQ guest loading in the MOF host by effectively removing the residual solvents and (2) postannealing of the TCNQ-infiltrated MOF to enhance the interaction of the confined guest molecules with the MOF host. The obtained experimental results based on thermogravimetric analysis, N2 gas adsorption, electron microscopy, X-ray diffraction, and infrared absorption, combined with density functional theory calculations provide evidence that the use of a stepwise thermal annealing process yields enhancements in the guest loading, packing, and interaction between the TCNQ guest and the MOF host. The new hybrid TCNQ@Cu3(BTC)2 system is stable and shows no significant signs of structural degradation even after submersion in water. This is due to the significantly stronger interactions of TCNQ with the framework metal ions compared to those of the water molecules competing for the same framework binding sites. It was also found that the TCNQ@Cu3(BTC)2 system maintains a significant CO2 and CH4 adsorption potential compared to the pristine MOF. The synthetic route developed in this work yields novel guest@MOF hybrid systems that will be useful for many MOF-based applications such as gas separations and chemical sensors working under humid conditions.
Micromachined spinneret (2023)

A micromachined spinneret is disclosed which has one or more orifices through which a fiber-forming material can be extruded to form a fiber. Each orifice is surrounded by a concentric annular orifice which allows the fiber to be temporarily or permanently coated with a co-extrudable material. The micromachined spinneret can be formed by a combination of surface and bulk micromachining.
Data from The Anaplastic Lymphoma Kinase Controls Cell Shape and Growth of Anaplastic Large Cell Lymphoma through Cdc42 Activation (2023)

&lt;div&gt;Abstract&lt;p&gt;Anaplastic large cell lymphoma (ALCL) is a non-Hodgkin's lymphoma that originates from T cells and frequently expresses oncogenic fusion proteins derived from chromosomal translocations or inversions of the anaplastic lymphoma kinase (&lt;i&gt;ALK&lt;/i&gt;) gene. The proliferation and survival of ALCL cells are determined by the ALK activity. Here we show that the kinase activity of the nucleophosmin (NPM)-ALK fusion regulated the shape of ALCL cells and F-actin filament assembly in a pattern similar to T-cell receptor–stimulated cells. NPM-ALK formed a complex with the guanine exchange factor VAV1, enhancing its activation through phosphorylation. VAV1 increased Cdc42 activity, and in turn, Cdc42 regulated the shape and migration of ALCL cells. &lt;i&gt;In vitro&lt;/i&gt; knockdown of VAV1 or Cdc42 by short hairpin RNA, as well as pharmacologic inhibition of Cdc42 activity by secramine, resulted in a cell cycle arrest and apoptosis of ALCL cells. Importantly, the concomitant inhibition of Cdc42 and NPM-ALK kinase acted synergistically to induce apoptosis of ALCL cells. Finally, Cdc42 was necessary for the growth as well as for the maintenance of already established lymphomas &lt;i&gt;in vivo&lt;/i&gt;. Thus, our data open perspectives for new therapeutic strategies by revealing a mechanism of regulation of ALCL cell growth through Cdc42. [Cancer Res 2008;68(21):8899–907]&lt;/p&gt;&lt;/div&gt;
Functionalized ZnO nanoparticles for thin-film transistors: support of ligand removal by non-thermal methods (2013)

A new approach is presented which allows substantial reduction of the process temperature of zinc oxide nanoparticles to generate semiconducting thin films. Functionalization is used to allow facile dispersion and to prevent agglomeration of the particles. Since charge transport is impeded by an insulating shell of octylamine the functionalization needs to be removed. Particles are deposited by spin-coating and the resulting film is exposed to different treatments. It is shown that plain annealing processes require high temperatures to fully remove the capping agents. The method presented in this work is a combination of UV irradiation of the wet films before annealing to cleave the octylamine and a vacuum process to aid the removal of organic residues. The effectiveness of the method is proven by electrical characterization.
Les députés, leurs assistants et les usages du crédit collaborateurs. Une sociologie du travail politique (2008)

Cet article propose une analyse des modes d’organisation des équipes parlementaires et étudie les tâches déléguées par les députés à leurs collaborateurs directs, les assistants parlementaires. L’analyse de la répartition des tâches au sein de ces équipes suggère que l’organisation et la division du travail doivent se comprendre principalement à partir des contraintes électorales pesant sur les députés en circonscription. La majorité des collaborateurs parlementaires y est affectée parce que l’exercice du métier de député implique le développement d’intenses relations de service en direction des électeurs. Les équipes parlementaires sont tellement sollicitées par les électeurs pour résoudre les problèmes personnels les plus divers qu’elles sont contraintes de développer des stratégies de régulation de la demande et d’y répondre souvent de manière symbolique. L’entretien de ces relations, qui rejaillit jusque dans le travail législatif, apparaît pour les députés comme un moyen de réduire le risque professionnel inhérent à une carrière élective. L’auteur montre l’adaptation des députés à un mode de scrutin qui les incite à adopter une conception de la représentation plus proche du porte-parole des habitants de la circonscription que du représentant de la Nation.
Phorbol ester 12- O -tetradecanoylphorbol-13-acetate down-regulates expression of the c-kit proto-oncogene product. (1993)

Modulation of expression of the c-kit proto-oncogene product, the receptor for the recently identified stem cell factor, was studied on 12-O-tetradecanoylphorbol-13-acetate (TPA)-stimulated cultures of CD34+ normal bone marrow progenitor cells, blast cells from patients with primary acute myelogenous leukemia, cells from the leukemia cell lines HEL and MO7E, as well as cultured HMC-1 mast cells. Expression of c-kit was assessed on both RNA and protein level employing standard Northern blotting, reverse transcription, and polymerase chain reaction-based Southern blotting, as well as cell surface labeling with anti-c-kit mAb YB5.B8. Treatment of virtually all cell types with nontoxic concentrations of TPA (10(-9) M) for at least 48 h was associated with down-regulation of synthesis of c-kit transcripts and stem cell factor-receptor surface expression. Studies on the mechanism of action of TPA utilizing the HEL erythroleukemia line showed that TPA was primarily acting by accelerating the turnover of c-kit RNA most likely through induction of a destabilizing protein. The effect of TPA on c-kit expression levels was independent of TPA-mediated induction of differentiation since other compounds including IFN-gamma, vitamin D3, retinoic acid, arabinofuranosylcytosine, butyric acid, and camptothecin, which also effectively induced differentiation of HEL cells, failed to alter levels of c-kit expression.
A standard clinical instrument interface for robotic applications (1990)

Many clinical laboratory instruments are not designed for robotic compatibility, hence the need for standardization of data communications and analyzer interface hardware. We developed an interface with supporting software that simplifies communication between a microcomputer and clinical instruments. Our interface establishes a standardized bidirectional communications protocol, which is useful in many clinical laboratory robotic projects. Instruments targeted for interfacing require no prior on-board communications capabilities. Additionally, modifications to the clinical instrument are minimized. Once installed, the interface translates input commands to codes or actions recognizable by the analyzer. Features not normally available to the user, such as electrode real-time response and full instrument status, are also reported by the interface, thereby establishing a remote monitor and control mechanism for the interfaced instrument. We have written an operating system to control the interface microcomputer, which in turn commands and monitors the clinical analyzer. A host computer controls the information flow to the interface and provides (a) requests to the interface for instrument operation and status and (b) commands to the interface to initiate the desired instrument operation. This arrangement maintains complete instrument functionality as designed by the manufacturer while allowing remote monitoring and operation of the instrument.
Average field map image template for Echo-Planar image analysis (2008)

Magnetic resonance field map images are normally used in characterizing the magnetic field inhomogeneity for distortion correction in Echo-Planar Imaging (EPI) and accurate localization in functional MRI (fMRI). In this paper, the computation and applications of an average field map image template is investigated based on real field maps. The introduced methodology and the obtained field map image templates may be used in EPI and fMRI image analysis, distortion correction, registration, and functional localization when high-resolution field map images are not available for individual datasets. The introduced methodology involves three stages of pre-processing, registration, and spatial normalization. The analysis and results presented in this paper show the impact and usefulness of the investigated methodology in several applications.
Wave-Field Shaping in Cavities: Waves Trapped in a Box with Controllable Boundaries (2015)

Electromagnetic cavities are used in numerous domains of applied and fundamental physics, from microwave ovens and electromagnetic compatibility to masers, quantum electrodynamics (QED), and quantum chaos. The wave fields established in cavities are statically fixed by their geometry, which are usually modified by using mechanical parts like mode stirrers in reverberation chambers or screws in masers and QED. Nevertheless, thanks to integral theorems, tailoring the cavity boundaries theoretically permits us to design at will the wave fields they support. Here, we show in the microwave domain that it is achievable dynamically simply by using electronically tunable metasurfaces that locally modify the boundaries, switching them in real time from Dirichlet to Neumann conditions. We prove that at a high modal density, counterintuitively, it permits us to create wave patterns presenting hot spots of intense energy. We explain and model the physical mechanism underlying the concept, which allows us to find a criterion ensuring that modifying parts of a cavity's boundaries turn it into a completely different one. We finally prove that this approach even permits us, in the limiting case where the cavity supports only well-separated resonances, to choose the frequencies at which the latter occur.
Conceptualized Use of Self-Expanding Foam to Rescue Special Operators From Abdominal Exsanguination: Percutaneous Damage Control for the Forward Deployed (2015)

Presurgical exsanguination rescue with percutaneous foam damage control is safe and effective with a favorable risk-benefit profile in preclinical studies. Battlefield, presurgical use by SOF medical providers is conceptually possible. Adoption of the technology on the battlefield should proceed with SOF medical provider input.
Spatially weighted mutual information (SWMI) for registration of digitally reconstructed ex vivo whole mount histology and in vivo prostate MRI (2011)

In this work, we present a scheme for the registration of digitally reconstructed whole mount histology (WMH) to pre-operative in vivo multiprotocol prostate MR imagery (T2w and DCE) using spatially weighted mutual information (SWMI). Spatial alignment of ex vivo histological sections to pre-operative in vivo MRI for prostate cancer (CaP) patients undergoing radical prostatectomy is a necessary first step in the discovery of quantitative multiprotocol MRI signatures for CaP. This may be done by spatially mapping delineated extent of disease on ex vivo histopathology onto pre-operative in vivo MRI via image registration. Apart from the challenges in spatially registering multi-modal data (histology and MRI) on account of (a) modality specific differences, (b) deformation due to the endorectal coil and tissue loss on histology, another complication is that the ex vivo histological sections, in the lab, are usually obtained as quadrants. This means they need to be reconstituted as a pseudo-whole mount histologic section (WMHS) prior to registration with MRI. An additional challenge is that most registration techniques rely on availability of the pre-segmented prostate capsule on T2w MRI. The novel contribution of this paper is that it leverages a spatially weighted mutual information (SWMI) scheme to automatically register and map CaP extent from WMHS onto pre-operative, multiprotocol MRI. The SWMI scheme obviates the need for pre-segmentation of the prostate capsule on MRI. Additionally, we leverage a program developed by our group, Histostitcher©, for interactive stitching of individual histology quadrants to digitally reconstruct the pseudo WMHS. Our registration methodology comprises the following main steps, (1) affine registration of T2w and DCE MRI, (2) affine registration of stitched WMHS to multiprotocol T2w and DCE MRI, and (3) multimodal image registration of WMHS to multiprotocol T2w and DCE MRI using SWMI. We quantitatively and qualitatively evaluated all aspects of our methodology in the multimodal registration of a total of 7 corresponding histology and MRI sections from 2 different patients. For the 7 studies, we obtained an average Hausdorff distance of 1.85 mm, mean absolute distance of 0.99 mm, RMS of 1.65 mm, and DICE of 0.83, when comparing the capsular alignment on MRI to histology.
Supplementary Figure 1 from Transient Antiangiogenic Treatment Improves Delivery of Cytotoxic Compounds and Therapeutic Outcome in Lung Cancer (2023)

&lt;p&gt;PDF file - 721KB, Imaging of tumor cell proliferation using 18FFLT PET in PC9 tumors.&lt;/p&gt;
Thermal gelling polyalanine-poloxamine-polyalanine aqueous solution for chondrocytes 3D culture: Initial concentration effect (2010)

Three dimensional (3D) cell culturing in an artificial matrix needs understanding of the dynamic microenvironments of the extracellular matrix and the cells. In this paper, we investigated a thermal gelling polyalanine–poloxamer–polyalanine (PA–PLX–PA) aqueous solution for chondrocyte 3D culture, focusing on the initial concentration of the polymer aqueous solution. As the polymer concentration increased from 7.0 wt. % to 10.0 wt. % and 15.0 wt. %, moduli of the in situ formed gels at 37 °C were increased from 350–380 Pa to 2100–2300 Pa and 5300–5700 Pa, respectively. In addition, the population and thickness of the nanofibers in the gel were increased. Chondrocytes kept their spherical phenotypes in the 3D environment of the in situ formed PA–PLX–PA hydrogel. They showed excellent cell viability, increased production of sGAG and type II collagen in PA–PLX–PA gel prepared from initial polymer concentration of 7.0 wt. % and 10.0 wt. %, emphasizing the significance of the micromechanical environments for the 3D cell culture.
CdSe tetrapod interfacial layer for improving electron extraction in planar heterojunction perovskite solar cells (2018)

We demonstrate the improvement in the efficiency of planar heterojunction perovskite solar cells by employing cadmium selenide tetrapods (CdSe TPs) as an electron extraction layer. The insertion of the CdSe TP layer between the titanium oxide (TiO<sub>2</sub>) and perovskite film facilitates electron transfer at the TiO<sub>2</sub>/perovskite interface, as indicated by the significantly quenched steady-state photoluminescence of the perovskite film. Furthermore, we observed a conductivity enhancement of the perovskite film by introducing the CdSe TP layer. The combination of both effects induced by the TPs leads to enhancement in the carrier extraction as well as decreased recombination losses in the perovskite solar cells. As a result, an efficiency of 13.5% (1 sun condition) is achieved in the perovskite solar cells that incorporate the CdSe TP layer, which is 10% higher than that of the device without the CdSe TP layer.
Biobleaching of Pulp with Dioxygen in the Laccase-Mediator System. Part 1. Kinetics of Delignification (2000)

Summary Kinetics of pine kraft-AQ pulp delignification with the laccase-mediator system (LMS) and the effects of variable factors on the delignification were studied. The delignification was conducted in acetate buffer solution at pH 4.5 and at 40°C under atmospheric pressure. Only a part of the residual lignin could be removed in one-stage processes. Kinetics of kappa number reduction follows a pseudo-second order rate law with pulp consistency of 10 %, mediator charge of 0.1 mmole HOBT/g pulp and laccase charage of 10 U Coriolus laccase/g pulp. Kinetics of dioxygen uptake follows a pseudo-first order rate law up to first 8 hours of the reaction and a pseudo-zero order rate law at the reaction time of 8–24 hours. The amounts of dioxygen consumed per removal of one C 9 -unit equivalent of residual lignin is rather high, 1.5–2.5 mole, and increases with increasing reaction time. Experimental data show that side reactions between the Laccase-Mediator System and products of oxidative degradation of lignin strongly inhibit the delignification either by chemical or physical means or both. Removal of the degraded lignin fragments by alkaline extraction effectively restores the delignification of pulp with LMS. A four-stage process consisting of consecutive treatment of pulp with dioxygen-laccase-HOBT (LMS) followed by alkaline extraction (E), (LMS-E) 4 , decreased kappa number of a pine kraft-AQ pulp from 21.8 to less than 5. On the basis of the kinetic data, the mechanism of the pulp delignification with LMS is discussed.