gebhart/patrepeval huggingface dataset:
Management of Local-Regional Recurrence following Immediate Breast Reconstruction in Patients with Early Breast Cancer Treated without Postmastectomy Radiotherapy (2011)

Routine use of postmastectomy radiation therapy in this heterogeneous patient population should be discouraged to allow more patients to undergo immediate breast reconstruction and ease the burden on plastic surgeons who have had to confront the problems of reconstruction in the face of perioperative radiation in an ever-increasing number of patients.
Development of anti-idiotype monoclonal antibodies for Sialyl Le(a) antigen. (1992)

Anti-idiotype monoclonal antibodies (MoAbs) were developed for a carbohydrate antigen, Sialyl Le(a), by immunizing mice with an anti-Sialyl Le(a) MoAb, KM231 (mouse IgG1). The anti-idiotype MoAbs inhibited the binding of KM231 to Sialyl Le(a)-positive mucin protein, but did not affect the binding of another MoAb (mouse IgG1) which recognized a peptide epitope on the same mucin protein. The selected four anti-idiotype MoAbs bound to all of the five anti-Sialyl Le(a) MoAbs examined, but not to other MoAbs developed against Sialyl Le(a)-related carbohydrate antigens such as Le(a), Le(x), and Sialyl Le(x) blood type A, B, H antigens. Immunization of rats with one of the anti-idiotype MoAbs, of which the reactivity was remarkably inhibited by Sialyl Le(a) oligosaccharide, resulted in the induction of antibody (Ab3) to purified Sialyl Le(a) glycolipid. Taken together, one of the anti-idiotype MoAbs developed in this study was the first Ab2 beta-type anti-idiotype MoAb which carried the internal image of Sialyl Le(a) antigen. The positive reaction of tumor cells expressing Sialyl Le(a) antigen with the Ab3 gave rise to the possibility that the anti-idiotype MoAb would become an effective tool for active immunotherapy in patients with Sialyl Le(a)-positive tumor.
Magnetically Assisted Remote-controlled Endovascular Catheter for Interventional MR Imaging: In Vitro Navigation at 1.5 T versus X-ray Fluoroscopy (2014)

In this study, a MARC catheter for endovascular navigation under real-time MR imaging guidance was developed and tested. For catheterization of branch vessels arising at large angles, magnetically assisted catheterization was faster than manual catheterization under MR imaging guidance and was comparable to standard x-ray guidance.
Key aspects of stratospheric tracer modeling using assimilated winds (2006)

Abstract. This study describes key aspects of global chemistry-transport models and their impact on stratospheric tracer transport. We concentrate on global models that use assimilated winds from numerical weather predictions, but the results also apply to tracer transport in general circulation models. We examined grid resolution, numerical diffusion, air parcel dispersion, the wind or mass flux update frequency, and time interpolation. The evaluation is performed with assimilated meteorology from the "operational analyses or operational data" (OD) from the European Centre for Medium-Range Weather Forecasts (ECMWF). We also show the effect of the mass flux update frequency using the ECMWF 40-year re-analyses (ERA40). We applied the three-dimensional chemistry-transport Tracer Model version 5 (TM5) and a trajectory model and performed several diagnoses focusing on different transport regimes. Covering different time and spatial scales, we examined (1) polar vortex dynamics during the Arctic winter, (2) the large-scale stratospheric meridional circulation, and (3) air parcel dispersion in the tropical lower stratosphere. Tracer distributions inside the Arctic polar vortex show considerably worse agreement with observations when the model grid resolution in the polar region is reduced to avoid numerical instability. The results are sensitive to the diffusivity of the advection. Nevertheless, the use of a computational cheaper but diffusive advection scheme is feasible for tracer transport when the horizontal grid resolution is equal or smaller than 1 degree. The use of time interpolated winds improves the tracer distributions, particularly in the middle and upper stratosphere. Considerable improvement is found both in the large-scale tracer distribution and in the polar regions when the update frequency of the assimilated winds is increased from 6 to 3 h. It considerably reduces the vertical dispersion of air parcels in the tropical lower stratosphere. Strong horizontal dispersion is not necessarily an indication of poor wind quality, as observations indicate. Moreover, the generally applied air parcel dispersion calculations should be interpreted with care, given the strong sensitivity of dispersion with altitude. The results in this study provide a guideline for stratospheric tracer modeling using assimilated winds. They further demonstrate significant progress in the use of assimilated meteorology in chemistry-transport models, relevant for both short- and long-term integrations.
Near-Infrared Fieldoscopy of Water (2019)

Linear near-infrared (NIR) spectroscopy provides information on the molecular composition, structure, and conformation, affording remarkable potential for high-resolution, in-depth, label-free biological spectro-microscopy [1]. Broadband measurements in NIR have been carried out in the frequency domain. However, in this approach, the detection of small absorption differences is limited to the intensity noise of the source, and the detection dynamic range.
Investigating the Biosynthetic Pathways to Polyacetylenic Natural Products in Fistulina hepatica and Echinacea purpurea (2013)

Polyacetylenic natural products, compounds containing multiple carbon-carbon triple bonds, have been found in a large collection of organisms. Radiochemical tracer studies have indicated that these bioactive metabolites are synthesized from fatty acid precursors through a series of uncharacterized desaturation and acetylenation steps. To date, there are three main pathways believed to be involved in acetylenic natural product biosynthesis. However, it is apparent that the crepenynic acid pathway is the origin of a vast majority of the known plant and fungal acetylenic products. This investigation provides concrete evidence that the polyacetylenic natural products found in the fungus Fistulina hepatica and the medicinal plant species Echinacea purpurea are biosynthesized from crepenynic acid. Through heterologous expression in Yarrowia lipolytica, two acetylenases capable of producing crepenynic acid were identified from E. purpurea. Furthermore, heterologous expression of two diverged desaturases isolated from F. hepatica, uncovered a ∆12-acetylenase and the first multifunctional enzyme capable of ∆14-/∆16- desaturation and ∆14-acetylenation.
Laboratory testing of the Mini-Magnetospheric Plasma Propulsion (M2P2) prototype (2001)

Mini-Magnetospheric Plasma Propulsion (M2P2) seeks the creation of a magnetic wall or bubble (i.e., a magnetosphere) attached to a spacecraft that will intercept the solar wind and thereby provide high-speed propulsion with little expenditure of propellant. Results from a laboratory prototype that demonstrate the basic formation and expansion of a mini-magnetosphere are presented. The prototype uses a helicon source embedded asymmetrically in a dipole-like magnetic field. Breakdown of the plasma can be produced at neutral pressures of between about 0.25 to 1 mTorr to produce plasma densities of the order of 1011–1012 cm−3 with a temperature of a few eV. The plasma pressure is sufficient to cause the outward expansion or inflation of the mini-magnetosphere. The motion of both open and closed field lines within the vacuum chamber is demonstrated through the optical emissions from the helicon plasma. Inflation of the magnetosphere to several feet away from the magnetic coil and the equatorial confinement of the plasma are demonstrated. In space, inflation to about 15–20 km would be expected for the same configuration, which would potentially lead to the acceleration a 70–140 kg payload to speeds of about 50–80 km/s over a 3-month acceleration period. At this speed, missions to the heliopause and beyond can be achieved in under 10 yrs.
ITQ-4: a new large pore microporous polymorph of silica (1997)

M. A. Camblor, A. Corma and L. A. Villaescusa, Chem. Commun., 1997, 749 DOI: 10.1039/A700672A
Record high current density and low contact resistance in MoS2 FETs by ion doping (2016)

Record high current density of 300 μA/μm with low contact resistance of 200 Ω μm and a channel length of 0.8 μm at a drain-source bias of 1.6 V has been achieved for the first time in MoS <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> field-effect transistors (FETs) grown by chemical vapor transport. The low contact resistance is achieved using a polyethylene-oxide cesium-perchlorate solid polymer ion conductor formed by drop casting. The charged ions are placed into position over the channel by the application of a bias to a side gate and then locked into place by lowering the temperature. A weak temperature dependence of the drain current after ion doping indicates that transport in the Schottky contacts is dominated by tunneling.
Staphylococcus p seudintermedius Isolated from Two Dog Cases with Ophthalmic Lesions (2017)

Two dog cases with history of recurrent bacterial conjunctivitis were submitted to Purdue University for bacterial culture and sensitivity testing. The bacterial cultures were also tested for their ability to form a biofilm. Biofilm forming Staphylococcus pseudintermedius was isolated from the two cases and identified by Vitek2 and PCR analysis. The bacterial antibiotic sensitivity testing revealed that Isolate one was susceptible to ticarcillin, ceftiofur, cefazolin, moxifloxacin, amikacin and rifampicin with MICs ranging 0.03125-4 μg/ml. Isolate two was susceptible to ceftiofur, gatifloxacin, cefazolin, moxifloxacin, tetracycline, doxycycline and rifampicin with MICs ranging <0.0625–4 μg/ml. Meanwhile, the biofilm antibiotic sensitivity testing revealed that Isolate one biofilm was resistant to all antibiotics except for ceftiofur and moxifloxacin with MICs <0.25 and 8 μg/ml respectively. Isolate two biofilm was resistant to all antibiotics except for tetracycline, amikacin, doxycycline, chloramphenicol and rifampicin with MICs ranged from <0.125 to 8 μg/ml. Case one was resolved with topical cefazolin therapy. Meanwhile case two showed complete recovery after treated with topical levofloxacin plus oral doxycycline.
Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons (2015)

In mammals, the hormone melatonin is mainly produced by the pineal gland with nocturnal peak levels. Its peripheral and central actions rely either on its intrinsic antioxidant properties or on binding to melatonin MT1 and MT2 receptors, belonging to the G protein-coupled receptor (GPCR) super-family. Melatonin has been reported to be involved in many functions of the central nervous system such as circadian rhythm regulation, neurotransmission, synaptic plasticity, memory, sleep, and also in Alzheimer's disease and depression. However, little is known about the subcellular localization of melatonin receptors and the molecular aspects involved in neuronal functions of melatonin. Identification of protein complexes associated with GPCRs has been shown to be a valid approach to improve our understanding of their function. By combining proteomic and genomic approaches we built an interactome of MT1 and MT2 receptors, which comprises 378 individual proteins. Among the proteins interacting with MT1 , but not with MT2 , we identified several presynaptic proteins, suggesting a potential role of MT1 in neurotransmission. Presynaptic localization of MT1 receptors in the hypothalamus, striatum, and cortex was confirmed by subcellular fractionation experiments and immunofluorescence microscopy. MT1 physically interacts with the voltage-gated calcium channel Cav 2.2 and inhibits Cav 2.2-promoted Ca(2+) entry in an agonist-independent manner. In conclusion, we show that MT1 is part of the presynaptic protein network and negatively regulates Cav 2.2 activity, providing a first hint for potential synaptic functions of MT1.
Octave-Spanning Tunable Frequency Combs on a Chip (2010)

We demonstrate direct full-octave spanning frequency comb generation via four-wave mixing in continuous wave laser pumped microresonators for the first time. The generated comb lines are fully tunable over more than one free spectral range.
Multi-rate short track-seeking control of hard disk drives for computation saving (2004)

This paper proposes a design method for short track-seeking control based on one-degree-of-freedom (ODOF) control and initial value compensation (IVC). IVC utilizes non-zero initial values of the feedback controller to improve the step reference response of the ODOF tracking control system. This makes feedforward control unnecessary to shape the transient response of short track-seeking. As a result, the amount of computation during short track-seeking may be kept minimal. The proposed design method minimizes tracking errors in multi-rate control frame work for a step reference input taking into account the inter-sampling behavior. The effectiveness of the proposed method is shown by simulations.
Identification of Modeling Boundaries for SSR Studies in Series Compensated Power Networks (2017)

Given large-scale power networks with series compensation, the study of subsynchronous resonance (SSR) is a significant challenge, in practice, due to the model complexity and computation burden. To tackle these difficulties, this paper proposes a method to reduce a large-scale system to an equivalent model using a metric called damping sensitivity index. The proposed metric can quantitatively identify the boundaries of the equivalent model that ensure the accurate studies of SSR and reduce the computation burdens greatly. The effectiveness of the method is verified by its application to the SSR investigation of the modified IEEE New England 10-machine 39-bus system and 16-machine 68-bus system. The equivalent models obtained by the proposed method are compared with the original systems in terms of driving point impedances, electrical damping, and transient torques. These results obtained show that the equivalent models from the proposed method can reproduce the SSR dynamics of the original systems with a much shorter computation time.
Auxiliary Reference Samples for Extrapolating Spectral Reflectance from Camera RGB Signals (2022)

Surface spectral reflectance is useful for color reproduction. In this study, the reconstruction of spectral reflectance using a conventional camera was investigated. The spectrum reconstruction error could be reduced by interpolating camera RGB signals, in contrast to methods based on basis spectra, such as principal component analysis (PCA). The disadvantage of the interpolation method is that it cannot interpolate samples outside the convex hull of reference samples in the RGB signal space. An interpolation method utilizing auxiliary reference samples (ARSs) to extrapolate the outside samples is proposed in this paper. The ARSs were created using reference samples and color filters. The convex hull of the reference samples and ARSs was expanded to enclose outside samples for extrapolation. A commercially available camera was taken as an example. The results show that with the proposed method, the extrapolation error was smaller than that of the computationally time-consuming weighted PCA method. A low cost and fast detection speed for spectral reflectance recovery can be achieved using a conventional camera.
1248: Myostatin is Expressed in the Normal Tunica Albuginea and Peyronie's Fibrotic Plaque in Parallel to Myofibroblast Differentiation (2004)

You have accessJournal of UrologyPodium, Monday, May 10, 2004, 3:30 - 5:30 pm1 Apr 20041248: Myostatin is Expressed in the Normal Tunica Albuginea and Peyronie's Fibrotic Plaque in Parallel to Myofibroblast Differentiation Monica G. Ferrini, Thomas R. Magee, Dolores Vernet, Ansha Qian, Eliane G. Valente, Shalender Bhasin, Jacob Rajfer, and Nestor F. Gonzalez-Cadavid Monica G. FerriniMonica G. Ferrini More articles by this author , Thomas R. MageeThomas R. Magee More articles by this author , Dolores VernetDolores Vernet More articles by this author , Ansha QianAnsha Qian More articles by this author , Eliane G. ValenteEliane G. Valente More articles by this author , Shalender BhasinShalender Bhasin More articles by this author , Jacob RajferJacob Rajfer More articles by this author , and Nestor F. Gonzalez-CadavidNestor F. Gonzalez-Cadavid More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)38473-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1248: Myostatin is Expressed in the Normal Tunica Albuginea and Peyronie's Fibrotic Plaque in Parallel to Myofibroblast Differentiation." The Journal of Urology, 171(4S), p. 329 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 171Issue 4SApril 2004Page: 329 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Monica G. Ferrini More articles by this author Thomas R. Magee More articles by this author Dolores Vernet More articles by this author Ansha Qian More articles by this author Eliane G. Valente More articles by this author Shalender Bhasin More articles by this author Jacob Rajfer More articles by this author Nestor F. Gonzalez-Cadavid More articles by this author Expand All Advertisement PDF downloadLoading ...
N- and O-doped mesoporous carbons derived from rice grains: efficient metal-free electrocatalysts for hydrazine oxidation (2016)

Nitrogen and oxygen co-doped mesoporous carbons that can serve as metal-free electrocatalysts are synthesized via a novel synthetic route using milled rice as a precursor and colloidal silica as a template. The materials efficiently electrocatalyze the hydrazine oxidation reaction with only a small onset potential, while giving a high peak current density and showing good long-term stability.
Stability and convergence of TCP-like congestion controllers in a many-flows regime (2003)

With the rapid growth of Internet, parameter design and analysis for large-scale networks has become a topic of active interest. Since simulation of such large scale systems is not easy, deterministic fluid models have been widely used for both qualitative understanding of the behavior, as well as parameter design for such networks. In this paper, we first study a deterministic fluid model for Internet congestion control when there are multiple TCP-like flows present. We provide conditions under which such a system is globally asymptotically stable in the presence of feedback delay. We then study the corresponding system with the addition of web mice and other nonresponsive flows modeled as stochastic disturbances. We show that, when there are a large number of flows, choosing parameters based on the global stability criterion for the deterministic system (with the noise replaced by its mean value) ensures global stability for the stochastic system as well. Numerical examples and simulation results with some popular active queue management mechanisms validate the parameter choices from analysis. The results indicate that a system with multiple TCP-like flows is globally stable as long as the bandwidth-delay product per flow is not very small.
Low Computational Complexity Algorithm for Hand Gesture Recognition using mmWave RADAR (2022)

Radio detection and ranging (RADAR) technology has attracted a lot of attention recently, especially for hand gesture recognition. Contactless hand gesture recognition can be applied in many areas, such as in-car entertainment systems and clean room operations. In this work, a computationally efficient and fast hand gesture feature extraction approach based on frequency-modulated continuous-wave (FMCW) RADAR is proposed, which is highly beneficial for real-time applications. Unlike conventional image recognition, the features of the hand gesture are extracted directly in an efficient manner. Our approach adopts 2-dimensional Fast Fourier Transform (FFT) to form a Range-Doppler matrix, and background modelling to remove clutter. Furthermore, we use best bin selection to locate the target in the Range-Doppler matrix in order to obtain both range and velocity of targets. Fourier beam steering is employed to obtain the angle of targets. Four classifiers are trained to perform hand gesture recognition. Cross-validation is used to evaluate their performance. Experimental results indicate that the features extracted by our approach can be fed directly into the classifiers for recognition which leads to an average recognition accuracy of 98.74% across all classifiers. Compared to image based recognition, the additional feature extraction process can be skipped, saving significant processing time. Our approach could be useful in many areas such as in-car entertainment systems, smart homes and others.
High light-extraction efficiency GaN-based vertical injection LEDs with surface nipple array (2009)

The surface nipple arrays were formed by self-assembled polystyrene nano-spheres and inductively coupled plasma etching. The light output power of the vertical-injection LEDs with nipple array shows 68% enhancement than that of without the nipple array at a driving current of 350 mA.
Elementary Steps in Protein Folding (1999)

The mechanism of protein folding is under intense theoretical and experimental investigation. From stopped-flow mixing experiments we have detailed knowledge of processes slower than about 1 ms, but until recently little was known about folding and unfolding reactions on the microsecond to nanosecond time scale. The use of novel techniques allowed to explore the elementary steps in protein folding, such as intrachain diffusion and formation of alpha-helices, beta-hairpins and loop structures. This brief review discusses the time scales of these early elementary events which are crucial for the understanding of how proteins fold.
XOL-1, primary determinant of sexual fate in C. elegans , is a GHMP kinase family member and a structural prototype for a class of developmental regulators (2003)

In Caenorhabditis elegans, an X chromosome-counting mechanism specifies sexual fate. Specific genes termed X-signal elements, which are present on the X chromosome, act in a concerted dose-dependent fashion to regulate levels of the developmental switch gene xol-1. In turn, xol-1 levels determine sexual fate and the activation state of the dosage compensation mechanism. The crystal structure of the XOL-1 protein at 1.55 A resolution unexpectedly reveals that xol-1 encodes a GHMP kinase family member, despite sequence identity of 10% or less. Because GHMP kinases, thus far, have only been characterized as small molecule kinases involved in metabolic pathways, for example, amino acid and cholesterol synthesis, XOL-1 is the first member that controls nonmetabolic processes. Biochemical investigations demonstrated that XOL-1 does not bind ATP under standard conditions, suggesting that XOL-1 acts by a mechanism distinct from that of other GHMP kinases. In addition, we have cloned a XOL-1 ortholog from Caenorhabditis briggsae, a related nematode that diverged from C. elegans approximately 50-100 million years ago. These findings demonstrate an unanticipated role for GHMP kinase family members as mediators of sexual differentiation and dosage compensation and, possibly, other aspects of differentiation and development.