gebhart/patrepeval huggingface dataset:
Unobservable Monte Carlo planning for nonprehensile rearrangement tasks (2017)

In this work, we present an anytime planner for creating open-loop trajectories that solve rearrangement planning problems under uncertainty using nonprehensile manipulation. We first extend the Monte Carlo Tree Search algorithm to the unobservable domain. We then propose two default policies that allow us to quickly determine the potential to achieve the goal while accounting for the contact that is critical to rearrangement planning. The first policy uses a learned model generated from a set of user demonstrations. This model can be quickly queried for a sequence of actions that attempts to create contact with objects and achieve the goal. The second policy uses a heuristically guided planner in a subspace of the full state space. Using these goal informed policies, we are able to find initial solutions to the problem quickly, then continuously refine the solutions as time allows. We demonstrate our algorithm on a 7 degree-of-freedom manipulator moving objects on a table.
Serum levels of GM‐CSF are elevated in patients with thrombocytopenia (1996)

Serum levels of GM-CSF, IL-3 and IL-6 were measured in patients with immune thrombocytopenia (ITP), non-immune thrombocytopenia (NIT), autoimmune haemolytic anaemia (AIHA) and neutropenia. 8/10 children with ITP had elevated serum levels of GM-CSF (mean 18.4 pg/ml) while thrombocytopenic, but only two had detectable levels (mean 4.5 pg/ml) after normalization of the platelet count. In patients with NIT a significant inverse correlation between platelet count and serum levels of GM-CSF was observed. IL-3 and IL-6 levels were not significantly elevated in thrombocytopenic patients and only two of the nine patients with either AIHA or neutropenia had detectable levels of GM-CSF. Thus, GM-CSF may play a role in the response of severe thrombocytopenia.
Catalytic tail-to-tail dimerization of methyl acrylate using rhodium(III) catalysts (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCatalytic tail-to-tail dimerization of methyl acrylate using rhodium(III) catalystsMaurice Brookhart and Sylviane Sabo-EtienneCite this: J. Am. Chem. Soc. 1991, 113, 7, 2777–2779Publication Date (Print):March 1, 1991Publication History Published online1 May 2002Published inissue 1 March 1991https://pubs.acs.org/doi/10.1021/ja00007a076https://doi.org/10.1021/ja00007a076research-articleACS PublicationsRequest reuse permissionsArticle Views655Altmetric-Citations56LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
System exploration and technology demonstration of 3D Wafer-to-Wafer integrated STT-MRAM based caches for advanced Mobile SoCs (2020)

This paper analyzes the most feasible 3D integration and partitioning scheme for STT-MRAM based caches in an advanced Mobile SoC based on the process demonstration of the first ever functional 3D integrated STT devices. We present 3D partitioning schemes from a design -architecture perspective and Power Performance and Area (PPA) analysis is carried out for the 2D and 3D SoC designs with both SRAM and STT-MRAM caches. Our work shows that the PPA benefits from 3D Memory on Logic partitioning are magnified when it can be exploited to accommodate larger caches in general. We also show that STT-MRAM based 3D partitioned caches can exploit this potential increase in capacity to improve performance even more than SRAM. These 3D Wafer-to-Wafer (W2W) integrated STT-MRAM caches can result in up-to 30% performance improvement at 17% power and 15% footprint reduction for our target SoC.
On the Design and Miniaturization of Passive UHF RFID Transponder Antenna (2007)

International audience
Cumulative distribution networks and the derivative-sum-product\n algorithm (2012)

We introduce a new type of graphical model called a "cumulative distribution\nnetwork" (CDN), which expresses a joint cumulative distribution as a product of\nlocal functions. Each local function can be viewed as providing evidence about\npossible orderings, or rankings, of variables. Interestingly, we find that the\nconditional independence properties of CDNs are quite different from other\ngraphical models. We also describe a messagepassing algorithm that efficiently\ncomputes conditional cumulative distributions. Due to the unique independence\nproperties of the CDN, these messages do not in general have a one-to-one\ncorrespondence with messages exchanged in standard algorithms, such as belief\npropagation. We demonstrate the application of CDNs for structured ranking\nlearning using a previously-studied multi-player gaming dataset.\n
HiperJobViz: Visualizing Resource Allocations in High-Performance Computing Center via Multivariate Health-Status Data (2019)

Scheduling, visualizing, and balancing resource allocations in High-Performance Computing Centers are complicated tasks due to a large amount of data and the dynamic natures of the resource allocation problem. This paper introduces HiperJobViz, a visual analytic tool for visualizing the resource allocations of data centers for jobs, users, and usage statistics. The goals of this tool are: 1) to provide an overview of the current resource usages, 2) to track changes of resource usages by users, jobs, and hosts and 3) to provide a detailed view of the resource usage via multi-dimensional representation of health metrics, such as CPU temperatures, memory usage, and power consumption. To support these goals, our visual analytics tool provides a full range of interactive features, including details on demands, brushing and links, and filtering.
Al-2.63 Line Edge Roughness (Ler) (2021)

As increasingly smaller molecular materials and material structures are devised or developed for technological applications, the demands on the processes of lithography now routinely include feature sizes that are of the order of 10 nm. In reaching such a fine level of resolution, the methods of lithography have increased markedly in sophistication and brought into play 2terminology that is unfamiliar, on the one hand, to scientists tasked with the development of new lithographic materials or, on the other, to the engineers who design and operate the complex equipment that is required in modern-day processing. Publications produced by scientists need to be understood by engineers and vice versa, and these commonly arise from collaborative research that draws heavily on the terminology of two or more of the traditional disciplines. It is developments in polymer science and material science that lead progress in areas that cross traditional boundaries, such as microlithography. This document provides the exact definitions of a selection of unfamiliar terms that researchers and practitioners from different disciplines might encounter.
A Dual Approach of an Oil–Membrane Composite and Boron-Doped Diamond Electrode to Mitigate Biofluid Interferences (2021)

Electrochemical biosensors promise a simple method to measure analytes for both point-of-care diagnostics and continuous, wearable biomarker monitors. In a liquid environment, detecting the analyte of interest must compete with other solutes that impact the background current, such as redox-active molecules, conductivity changes in the biofluid, water electrolysis, and electrode fouling. Multiple methods exist to overcome a few of these challenges, but not a comprehensive solution. Presented here is a combined boron-doped diamond electrode and oil-membrane protection approach that broadly mitigates the impact of biofluid interferents without a biorecognition element. The oil-membrane blocks the majority of interferents in biofluids that are hydrophilic while permitting passage of important hydrophobic analytes such as hormones and drugs. The boron-doped diamond then suppresses water electrolysis current and maintains peak electrochemical performance due to the foulant-mitigation benefits of the oil-membrane protection. Results show up to a 365-fold reduction in detection limits using the boron-doped diamond electrode material alone compared with traditional gold in the buffer. Combining the boron-doped diamond material with the oil-membrane protection scheme maintained these detection limits while exposed to human serum for 18 h.
Analysis of optimum conditions of depolarization imaging by polarization-sensitive optical coherence tomography in the human retina (2015)

Measurement and imaging of depolarization by polarization-sensitive optical coherence tomography (PS-OCT) requires averaging of Stokes vector elements within two- or three-dimensional (3-D) evaluation windows to obtain the degree of polarization uniformity (DOPU). By use of a PS-OCT system with an integrated retinal tracker, we analyze optimum conditions for depolarization imaging, data processing, and segmentation of depolarizing tissue in the human retina. The trade-offs between figures of merit like DOPU imaging sensitivity, efficiency, and susceptibility are evaluated in terms of 3-D resolution. The results are used for a new, detailed interpretation of PS-OCT high-resolution images of the human retinal pigment epithelium and Bruch’s membrane.
Three-dimensional Polarization Ray Tracing, Retardance (2010)

The retardance associated with a three-by-three polarization ray tracing matrix P is analyzed. A method to separate the geometrical transformation from the “physical” retardance is presented using a non-polarizing ray tracing matrix Q.
PD40-09 A MULTIPARAMETRIC MAGNETIC RESONANCE IMAGING – BASED VIRTUAL REALITY SURGICAL AID FOR ROBOTIC – ASSISTED RADICAL PROSTATECTOMY (2018)

The incidence of iatrogenic urethral catheterization injuries (IUCI 0 s), wherein the retention balloon is inflated with the urethra, is e 6.7 per 1000 catheterizations, and is the reported incidence of CAUTI. Urethral catheters are placed by physicians and nurses with varying degree of catheter-expertise, from all specialties. The morbidity and financial cost of IUCI 0 s to the U.S. healthcare is substantial. We developed a novel catheter design to help prevent IUCI 0 s. Here we describe how we validated the final design, and compared performance of working prototypes to a standard BARD catheter using bench-top studies and using fresh transected penis specimens.
Hybrid nanocrystals-organic-semiconductor light sensor (2008)

We present a light sensing device based on nearly spherical, defect free colloidal nanocrystals (NCs) of InAs acting as a light activated gate for a GaAs∕AlGaAs field effect semiconductor transistor. We use self-assembled organic monolayer as linkers that attach the InAs NCs to the surface of the semiconductor device, instead of the gate that exists in common transistors. When the NCs absorb light, at a frequency corresponding to their resonance, a change in the current through the transistor takes place while no current flows through the NCs themselves.
Characterization and anti-tumor activity of a chimeric tetravalent anti-CD22 monoclonal antibody (2007)

903 A tetravalent chimeric anti-human CD22 antibody (cRFB4-TetraMAb) with improved anti-tumor activity has been developed. The DNA encoding the single chain Fv (scFv) was spliced to the Fc of human IgG1 and expressed in Chinese hamster ovary cells. The construct was purified on Sepharose- Protein G followed by HPLC. The characteristics of the cTetraMAb were analyzed and compared to its parental divalent MAb, RFB4. The TetraMAb bound to CD22+ Daudi cells as well as the divalent RFB4, but had a slower dissociation rate. Both the TetraMAb and the divalent RFB4 bound equally well to FcγR-positive human cells, to human C1q, and to recombinant human FcRn in vitro. It also had comparable ADCC activity when human effector cells were used. Despite its slightly larger size, the TetraMAb penetrated normal tissues in Swiss Webster mice as well as the divalent MAb. The TetraMAb had a longer half-life in both Swiss Webster mice and mFcRn-/hFcRn+ transgenic mice, and it showed improved anti-tumor activity in SCID mice xenografted with various CD22 positive human tumor cell lines. Moreover, the enhanced activity of the TetraMAb was dose-related. In conclusion, these data suggest that this tetravalent RFB4 antibody should be further developed for human use.
Transcriptome dynamics over a lunar month in a broadcast spawning acroporid coral (2017)

On one night per year, at a specific point in the lunar cycle, one of the most extraordinary reproductive events on the planet unfolds as hundreds of millions of broadcast spawning corals release their trillions of gametes into the waters of the tropical seas. Each species spawns on a specific night within the lunar cycle, typically from full moon to third quarter moon, and in a specific time window after sunset. This accuracy is essential to achieve efficient fertilization in the vastness of the oceans. In this report, we use transcriptome sequencing at noon and midnight across an entire lunar cycle to explore how acroporid corals interpret lunar signals. The data were interrogated by both time-of-day-dependent and time-of-day-independent methods to identify different types of lunar cycles. Time-of-day methods found that genes associated with biological clocks and circadian processes change their diurnal cycles over the course of a synodic lunar cycle. Some genes have large differences between day and night at some lunar phases, but little or no diurnal differences at other phases. Many clock genes display an oscillation pattern indicative of phase shifts linked to the lunar cycle. Time-independent methods found that signal transduction, protein secretion and modification, cell cycle and ion transport change over the lunar timescale and peak at various phases of the moon. Together these data provide unique insights into how the moon impinges on coral transcription cycles and how lunar light may regulate circalunar timing systems and coral biology.
Biosynthetic (recombinant) human granulocyte-macrophage colony- stimulating factor: effect on normal bone marrow and leukemia cell lines (1986)

To examine the biologic properties of the molecule encoded by the human gene for granulocyte-macrophage colony-stimulating factor (GM-CSF), we expressed the cloned complementary DNA (cDNA) in transfected monkey COS cells and purified the resultant protein. Purified biosynthetic human GM-CSF was added to cultures of normal hematopoietic progenitor cells in semisolid media, and the resulting colonies were characterized cytochemically. Non-adherent light-density bone marrow cells from healthy adult volunteers were maximally stimulated with GM-CSF (approximately 250 pmol/L, and four types of colonies were consistently identified by aspirating the individual colonies and staining with a triple stain for specific and nonspecific esterases and eosinophilic granules. Pure neutrophilic granulocyte (G), mixed granulocyte-macrophage (GM), pure macrophage (M), and pure eosinophil (EO) colonies were observed, the mean incidences on day 8 being 70%, 20%, 5%, and 5%, and on day 14, 7.5%, 16.6%, 50.9%, and 25.0%, respectively. In all types of colonies, complete maturation to segmented forms or typical macrophages was detected. GM-CSF did not enhance the growth of BFU-E from normal peripheral blood buffy coat cells in the simultaneous presence of erythropoietin alone or erythropoietin with purified erythroid-potentiating activity. GM-CSF stimulated HL-60 and KG-1 colony formation twofold and fivefold, respectively; consistent differentiation induction towards monocytic and eosinophilic lineages was observed in HL-60 but not in KG-1. These in vitro findings indicate that GM-CSF is a multilineage stimulator for progenitor cells of G, GM, M, and EO colonies.
The antihypoxia–adenosinergic pathogenesis as a result of collateral damage by overactive immune cells (2009)

Here, we attract attention to the possibility of iatrogenic exacerbation of immune-mediated tissue damage as a result of the unintended weakening of the tissue-protecting, hypoxia-adenosinergic pathway. These immunosuppressive, anti-inflammatory pathways play a critical and nonredundant role in the protection of normal tissues from collateral damage during an inflammatory response. We believe that it is the tissue hypoxia associated with inflammatory damage that leads to local inhibition of overactive immune cells by activating A2AR and A2BR and stabilizing HIF-1alpha. We show in an animal model of acute lung injury that oxygenation (i.e., inspiring supplemental oxygen) reverses tissue hypoxia and exacerbates ongoing inflammatory lung tissue damage. However, little has been done to carefully investigate and prevent this in a clinical setting. Similarly, the consumption of caffeine antagonizes A2ARs, resulting in exacerbation of ongoing acute inflammation. It is suggested that although the elimination of hypoxia-adenosinergic immunosuppression is desirable to improve vaccines, it is important to take into account the unintentional effects of supplemental oxygen and caffeine, which may increase collateral, inflammatory tissue damage.
On the Usage of Geolocation-Aware Spectrum Measurements for Incumbent Location and Transmit Power Detection (2015)

Determining the geographical area that needs to be excluded due to incumbent activity is critical to realize high spectral utilization in spectrum sharing networks. This can be achieved by estimating the incumbent location and transmit power. However, keeping the hardware complexity of sensing nodes to a minimum and scalability are critical for spectrum sharing applications with commercial intent. We present a discrete-space l <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> -norm minimization solution based on geolocation-aware energy detection measurements. In practice, the accuracy of geolocation tagging is limited. We capture the impact as a basis mismatch and derive the necessary condition that needs to be satisfied for successful detection of multiple incumbents' location and transmit power. We find the upper bound for the probability of eliminating the impact of limited geolocation tagging accuracy in a lognormal shadow fading environment, which is applicable to all generic I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sub> -norm minimization techniques. We propose an algorithm based on orthogonal matching pursuit that decreases the residual in each iteration by allowing a selected set of basis vectors to rotate in a controlled manner. Numerical evaluation of the proposed algorithm in a Licensed Shared Access (LSA) network shows a significant improvement in the probability of missed detection and false alarm.
A Different Reaction Pathway for the Reduction of Aromatic Nitro Compounds on Gold Catalysts (2007)

Ein Au/TiO2-Katalysator vermeidet die Bildung von Kondensationsprodukten bei der Hydrierung aromatischer Nitroverbindungen. Anhand von kinetischen Untersuchungen und In-situ-IR-Messungen, die belegen, dass nur geringe Mengen an Nitrosobenzol erzeugt werden und dass das Hydroxylamin und Nitrosobenzol stark mit der Katalysatoroberfläche wechselwirken, wurde eine neuartige Reaktionssequenz postuliert (siehe Bild). Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2007/z700823_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Topologically protected vortex knots and links (2022)

Abstract In 1869, Lord Kelvin found that the way vortices are knotted and linked in an ideal fluid remains unchanged in evolution, and consequently hypothesized atoms to be knotted vortices in a ubiquitous ether, different knotting types corresponding to different types of atoms. Even though Kelvin’s atomic theory turned out incorrect, it inspired several important developments, such as the mathematical theory of knots and the investigation of knotted structures that naturally arise in physics. However, in previous studies, knotted and linked structures have been found to untie via local cut-and-paste events referred to as reconnections. Here, in contrast, we construct knots and links of non-Abelian vortices that are topologically protected in the sense that they cannot be dissolved employing local reconnections and strand crossings. Importantly, the topologically protected links are supported by a variety of physical systems such as dilute Bose-Einstein condensates and liquid crystals. We also propose a classification scheme for topological vortex links, in which two structures are considered equivalent if they differ from each other by a sequence of topologically allowed reconnections and strand crossings, in addition to the typical continuous transformations. Interestingly, this scheme produces a remarkably simple classification.
Direct stimulation of ovarian progesterone-metabolizing enzyme by gonadotropin-releasing hormone in cultured granulosa cells. (1981)

The mechanism by which gonadotropin-releasing hormone (GnRH) inhibits ovarian progesterone production was investigated by studying the GnRH modulation of 20 alpha-hydroxysteroid dehydrogenase activity in cultured rat granulosa cells. The granulosa cells obtained from hypophysectomized, estrogen-treated rats were treated with various hormones in vitro and 20 alpha-hydroxysteroid dehydrogenase activity determined by measuring the conversion of radiolabeled 20 alpha-hydroxy-pregn-4-en-3-one to progesterone. Treatment with follicle-stimulating hormone (FSH) increased the 20 alpha-hydroxysteroid dehydrogenase activity of granulosa cells to 1.3-fold of the control value. Concomitant treatment with 10(-8) M GnRH further enhanced the FSH stimulation of enzyme activity to 2.6-fold of the control value. The increases in 20 alpha-hydroxysteroid dehydrogenase activity were associated with increases in maximum velocity, while the Km values remained unchanged. In contrast, prolactin (PRL) treatment of FSH-primed granulosa cells resulted in an 88% decrease in 20 alpha-hydroxysteroid dehydrogenase activity as compared to untreated controls. Concomitant treatment with GnRH partially blocked this inhibitory effect. Furthermore, incubation of granulosa cells for 2 days with GnRH alone resulted in a 2.7-fold increase in 20 alpha-hydroxysteroid dehydrogenase activity, as compared to untreated controls. In all experiments, the effect of GnRH was blocked by concomitant treatment with a GnRH antagonist. These results suggest that one mechanism by which GnRH inhibits FSH- and PRL-stimulated progesterone production in granulosa cells is through the stimulation of the activity of 20 alpha-hydroxysteroid dehydrogenase which converts progesterone to a less active metabolite.