gebhart/patrepeval huggingface dataset:
Brassinosteroids Induce Strong, Dose-Dependent Inhibition of Etiolated Pea Seedling Growth Correlated with Ethylene Production (2019)

We have recently discovered that brassinosteroids (BRs) can inhibit the growth of etiolated pea seedlings dose-dependently in a similar manner to the 'triple response' induced by ethylene. We demonstrate here that the growth inhibition of etiolated pea shoots strongly correlates with increases in ethylene production, which also responds dose-dependently to applied BRs. We assessed the biological activities of two natural BRs on pea seedlings, which are excellent material as they grow rapidly, and respond both linearly and uni-phasically to applied BRs. We then compared the BRs' inhibitory effects on growth, and induction of ethylene and ACC (1-aminocyclopropane-1-carboxylic acid) production, to those of representatives of other phytohormone classes (cytokinins, auxins, and gibberellins). Auxin induced ca. 50-fold weaker responses in etiolated pea seedlings than brassinolide, and the other phytohormones induced much weaker (or opposite) responses. Following the optimization of conditions for determining ethylene production after BR treatment, we found a positive correlation between BR bioactivity and ethylene production. Finally, we optimized conditions for pea growth responses and developed a new, highly sensitive, and convenient bioassay for BR activity.
VIEUX PHENOTYPE ET NOUVEAUX GENOTYPES Actualités dans le domaine des adénomes hypophysaires (2015)

peer reviewed
Biocomposite Implants Composed of Poly(Lactide‐ co ‐Glycolide)/β‐Tricalcium Phosphate: Systematic Review of Imaging, Complication, and Performance Outcomes (2016)

Level IV, systematic review of Level I-IV studies.
Fargesin improves lipid and glucose metabolism in 3T3‐L1 adipocytes and high‐fat diet‐induced obese mice (2012)

This study examined the effects of fargesin, a neolignan isolated from Magnolia plants, on obesity and insulin resistance and the possible mechanisms involved in these effects in 3T3-L1 adipocytes and high-fat diet (HFD)-induced obese mice. Fargesin promoted the glucose uptake in 3T3-L1 adipocytes. In HFD-induced obese mice, fargesin decreased the body weight gain, white adipose tissue (WAT), and plasma triglyceride, non-esterified fatty acid and glucose levels, and improved the glucose tolerance. Fargesin increased glucose transporter 4 (GLUT4) protein expression and phosphorylation of Akt, AMP-activated protein kinase (AMPK), and acetyl-CoA carboxylase (ACC) in both 3T3-L1 adipocytes and WAT of HFD-induced obese mice. Fargesin also decreased the mRNA expression levels of fatty acid oxidation-related genes, such as peroxisome proliferator-activated receptor α (PPARα), carnitine palmitoyltransferase-1 (CPT-1), uncoupling protein-2 (UCP-2) and leptin in WAT. Taken together, the present findings suggest that fargesin improves dyslipidemia and hyperglycemia by activating Akt and AMPK in WAT.
Growth of Noble Metal Ru Thin Films by Liquid Injection Atomic Layer Deposition (2009)

Ru thin films were deposited by liquid injection atomic layer deposition (LIALD) with tris(2,2,6,6-tetramethyl-3,5-heptanedionato)ruthenium dissolved in ethylcyclohexane (ECH) and oxygen at growth temperatures of 330 and 380 °C. The film thickness is clearly saturated with increasing the injected volume of Ru solution. However, the value of the saturated film thickness at a certain cycle decreased when decreasing the concentration of a Ru solution from 0.05 to 0.01 M. Additionally, the film thickness decreased with increasing the flow rate and feeding time of O2. All films that were deposited at 380 °C were metallic Ru films not RuO2. Even at a low temperature of 330 °C, a very large amount and long time feeding of O2 was required to form a detectable amount of RuO2 phase. This phenomenon, which is unique for the LIALD Ru process, is consistently explained by a reduction of adsorbed oxygen atoms by ECH during feeding of the Ru solution. The adsorbed oxygen atoms are removed from the subsurface because the equilibrium oxygen partial pressure for oxidation of noble metals such as Ru is relatively high. Therefore, LIALD is effective in reducing the content of the corresponding oxides in noble metal films.
A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation—part 2: systematic review of evidence regarding resection extent in generally healthy patients (2022)

A systematic, comprehensive summary of evidence regarding resection extent in healthy patients with attention to aspects of applicability, uncertainty and effect modifiers provides a foundation on which to build a framework for individualized clinical decision-making.
X-Ray Observation of a Stacked Hexatic Liquid-CrystalBPhase (1981)

X-ray studies have been performed on a new liquid-crystal material which exhibits a noncrystalline $B$ phase. Using free-standing liquid-crystal film techniques, we find that this $B$ phase has short-range in-plane positional correlations but long-range, three-dimensional, sixfold bond-orientational order. We interpret our results in terms of a system of interacting two-dimensional hexatic layers.
-158-INTEGRATED, FREQUENCY DOMAIN CHARACTERIZATION OF SYSTEMIC AND PULMONARY VENOUS RETURN IN ACUTE OPEN CHEST DOGS (1986)

and end3ystolic pressure vs stroke voLume relationship C-Ea) by the sirnultaneous recordings of arterial pressure and left ventricular echocardiograrn.
Special Issue on Light Communications: Latest Advances and Prospects (2022)

The wireless information carrier shift from the radio frequencies to optical frequencies has been studied in increasing detail since the invention of the laser in the 1960s [...]
Where computer vision can aid physics: dynamic cloud motion forecasting\n from satellite images (2017)

This paper describes a new algorithm for solar energy forecasting from a\nsequence of Cloud Optical Depth (COD) images. The algorithm is based on the\nfollowing simple observation: the dynamics of clouds represented by COD images\nresembles the motion (transport) of a density in a fluid flow. This suggests\nthat, to forecast the motion of COD images, it is sufficient to forecast the\nflow. The latter, in turn, can be accomplished by fitting a parametric model of\nthe fluid flow to the COD images observed in the past. Namely, the learning\nphase of the algorithm is composed of the following steps: (i) given a sequence\nof COD images, the snapshots of the optical flow are estimated from two\nconsecutive COD images; (ii) these snapshots are then assimilated into a\nNavier-Stokes Equation (NSE), i.e. an initial velocity field for NSE is\nselected so that the corresponding NSE' solution is as close as possible to the\noptical flow snapshots. The prediction phase consists of utilizing a linear\ntransport equation, which describes the propagation of COD images in the fluid\nflow predicted by NSE, to estimate the future motion of the COD images. The\nalgorithm has been tested on COD images provided by two geostationary\noperational environmental satellites from NOAA serving the west-hemisphere.\n
What kinds of “things” should be considered in designing trust for IoTs applications?: A multi-disciplinary review (2015)

IoTs (Internet of Things) aims at connecting everything around consumers. However, inevitable concerns about privacy, risk and uncertainty arise over IoTs applications. Thus, how to make consumers trust in IoTs applications is a big challenge. Current study argues how to build and design trust for IoTs applications by reviewing previous literatures in various academic fields. Based on a multi-disciplinary review, we discuss what should be considered in designing trust for IoTs applications.
Digital Etching of GaAs Materials: Comparison of Oxidation Treatments (2016)

Oxidation of a GaAs surface was performed with liquid H 2 O 2 , gaseous O 2 and O 3 in order to identify the best solution for digital etching. The oxide layer formed with H 2 O 2 is Garich and exhibits surface roughening which can be understood by oxide hydrolysis/condensation model. Roughening makes aqueous H 2 O 2 irrelevant as an oxidizing agent for repeated oxidation steps. On the other hand, a smooth oxide layer can be obtained with gaseous O 2 and O 3 . Thickness of the formed oxide layer is controlled by time exposure to the oxidizing agent. The nature of the oxide was analyzed by XRay Photo-electron Spectroscopy and is also timedependent.
Supplementary Figure S7 from Integrated Human and Murine Clinical Study Establishes Clinical Efficacy of Ruxolitinib in Chronic Myelomonocytic Leukemia (2023)

&lt;p&gt;Supplementary Figure S7 depicts a receiver operating characteristic curve evaluating the performance of patient-derived xenograft mouse survival as a predictor of response.&lt;/p&gt;
THE MORIS MOTORCYCLE SIMULATOR: AN OVERVIEW (2001)

&lt;span class="label"&gt;1&lt;/span&gt; &lt;div class="htmlview paragraph"&gt;Many motion based simulators have been developed in the last thirty years for many different types of vehicles [&lt;span class="xref"&gt;1&lt;/span&gt;] [&lt;span class="xref"&gt;2&lt;/span&gt;]. In order to make a simulation more realistic, linear accelerations and angular rates are exerted on the pilot by moving the platform on which the mock-up vehicle is located.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The purpose of this article is to present a 7 DOFs (vertical, lateral and longitudinal displacements, roll, pitch and yaw angles and steer) motorcycle simulator which has been realized in Pisa, Italy, in the framework of the Esprit project by a consortium composed by industrial partners (Piaggio and Humanware from Italy and HEAD acoustics from Germany) and by academic partners (Scuola Superiore S. Anna from Italy, Halmstad University from Sweden and University of Bochum from Germany).&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;Such project started in 1995 with the aim of developing a two-wheeled motorcycle simulator conceived as a tool for the designer to acquire data on motorcycle handling and stability at the design stage as well as to collect data about rider control behavior implications in motorcycle performances.&lt;/div&gt;
Multipartite high-dimensional entangled state generation through soliton-induced dynamical Casimir effect on a chip (2020)

An integrated photonic approach for complex quantum state generation through dynamical Casimir effect (DCE) is demonstrated. This approach provides a scheme to realize multipartite high-dimensional entangled states in the microwave (MW) and terahertz (THz) regimes, through the modulation in a MW-resonator coupled to an optical microresonator supporting temporal optical solitons. The states at the MW-resonator evolve from the ground state, realizing real-photons from the virtual photons at the ground state. The periodic modulation of the MW-resonator through a Kerr-induced refractive index change in the optical microresonator, along with the localized spatial distribution of the dissipative Kerr solitons (DKSs), enables photon-pair generation and inter-mode coupling at the MW-resonator. This allows generating highly persistent multipartite high-dimensional entangled states in a wide range of spectrum. The proposed approach paves the way for a hybrid integrated platform for generation of multipartite entangled qudits (high-dimensional qubits) at the MW and THz regimes using highly coherent ultra-short optical pulses in a monolithic integrated platform. This architecture can act as an entangled state source, as a necessary resource for exploiting a wide range of quantum protocols from fault-tolerant computing to enhanced sensing and teleportation.
Bone regeneration in minipigs via calcium phosphate cement scaffold delivering autologous bone marrow mesenchymal stem cells and platelet‐rich plasma (2017)

Macroporous calcium phosphate cement (CPC) with stem cell seeding is promising for bone regeneration. The objective of this study was to investigate the effects of co-delivering autologous bone marrow mesenchymal stem cells (BMSCs) and autologous platelet-rich plasma (PRP) in CPC scaffold for bone regeneration in minipigs for the first time. Twelve female adult Tibet minipigs (12-18 months old) were used. A cylindrical defect with 10 mm height and 8 mm diameter was prepared at the femoral condyle. Two bone defects were created in each minipig, one at each side of the femoral condyle. Three constructs were tested: (1) CPC scaffold (CPC control); (2) CPC seeded with BMSCs (CPC-BMSC); (3) CPC seeded with BMSCs and PRP (CPC-BMSC-PRP). Two time points were tested: 6 and 12 weeks (n = 4). Good integration of implant with surrounding tissues was observed in all groups. At 12 weeks, the CPC-BMSC-PRP group had significantly less residual CPC remaining in the defect than the CPC-BMSC group and the CPC control (p < 0.05). The residual CPC volume for the CPC-BMSC-PRP group was half that of the CPC control. New bone formation for CPC-BMSC-PRP was more than two-fold that of the CPC control (p < 0.05). CPC-BMSC-PRP had new blood vessel density that was nearly two-fold that of the CPC control (p < 0.05). In conclusion, CPC scaffold with autologous BMSC-PRP doubled the new bone regeneration and blood vessel density in minipigs compared with the CPC control. In the present study, the new macroporous CPC system with co-delivered BMSC-PRP has been shown to promote scaffold resorption and bone regeneration in large defects. Copyright © 2017 John Wiley & Sons, Ltd.
Additional file 1: of Folic acid tagged nanoceria as a novel therapeutic agent in ovarian cancer (2016)

Calculations to determine the wight of nanoparticles. (DOCX 13 kb)
Synthesis of bio-plasticizer from epoxidized vegetable oils (2014)

International @ CDFA+GSC:CPI:LDJ
Establishment of highly sensitive and wide-ranged immunoassay for TNF.ALPHA. by DELFIA. (1992)

Non-isotopic immunoassay for the human tumor necrosis factor α (TNFα) was established by employing the dissociated enhanced lanthanide fluoroimmunoassay (DELFIA) system, based on the timeresolved fluoroimmunoassay (TR-FIA) technique utilizing the europium-labeled antibody. In comparison with enzyme-linked immunosorbent assay and bioassay, the sensitivity and range of measurement could be significantly increased by applying the DELFIA system to TNFα.Biological samples, including serum, may affect some of the immunoassays. We overcome the serum influence to the measurement of TNFα by DELFIA, Percent recovery of additional TNFα in each diluted serum was determined, then the sliding standard curve of each serum sample was mathematically calculated from the recovery. Finally corrected TNFα amount was detected by using the sliding standard curve. We suggest that more accurate, sensitive and wide ranged TNFα immunoassay has been established by DELFIA with some revising calculation.
Wisconsin Wind Tunnel II: a fast, portable parallel architecture simulator (2000)

To analyze new parallel computers, developers must rapidly simulate designs running realistic workloads. Historically, direct execution and a parallel host have accelerated simulations, although these techniques have typically lacked portability. Through four key operations, the Wisconsin Wind Tunnel II can easily run simulations on Sparc platforms ranging from a workstation cluster to an asymmetric multiprocessor.
Strain-mediated 180° switching in CoFeB and Terfenol-D nanodots with perpendicular magnetic anisotropy (2017)

A micromagnetic and elastodynamic finite element model is used to compare the 180° out-of-plane magnetic switching behavior of CoFeB and Terfenol-D nanodots with perpendicular magnetic easy axes. The systems simulated here consist of 50 nm diameter nanodots on top of a 100 nm-thick PZT (Pby[ZrxTi1-x]O3) thin film, which is attached to a Si substrate. This allows voltage pulses to induce strain-mediated magnetic switching in a magnetic field free environment. Coherent and incoherent switching behaviors are observed in both CoFeB and Terfenol nanodots, with incoherent flipping associated with larger or faster applied switching voltages. The energy to flip a Terfenol-D memory element is an ultralow 22 aJ, which is 3–4 orders more efficient than spin-transfer-torque. Consecutive switching is also demonstrated by applying sequential 2.8 V voltage pulses to a CoFeB nanodot system with switching times as low as 0.2 ns.
Characteristics of the Alkaline-pretreated AB5 Type Hydrogen Storage Alloys as the Negative Electrode in Ni-MH Battery. (1997)

Study of the surface structures reformed by the alkaline treatment of the rare-earth metal based AB 5 type alloys
Novel Positive Polaron Stabilizing n-Type Host for High Efficiency and Long Lifetime in Blue Phosphorescent Organic Light-Emitting Diodes (2020)

Four electron transport type hosts withstanding the positive polaron stress were synthesized using the benzo[4,5]thieno[3,2-<i>d</i>]pyrimidine core to develop high triplet energy hosts. Four benzo[4,5]thieno[3,2-<i>d</i>]pyrimidine-derived hosts, 4-(9<i>H</i>-carbazol-9-yl)-2-(3-(triphenylsilyl)phenyl)benzo[4,5]thieno[3,2-<i>d</i>]pyrimidine (CzBTPmSi), 2,4-di(9<i>H</i>-carbazol-9-yl)benzo[4,5]thieno[3,2-<i>d</i>]pyrimidine (2CzBTP), 2-(9<i>H</i>-carbazol-9-yl)-4-(3-(triphenylsilyl)phenyl)benzo[4,5]thieno[3,2-<i>d</i>]pyrimidine (mSiBTPCz), and 2,4-bis(3-(triphenylsilyl)phenyl)benzo[4,5]thieno[3,2-<i>d</i>]pyrimidine (2mSiBTP), were designed to have either the tetraphenylsilyl blocking group or the hole transport type carbazole group. The CzBTPmSi and mSiBTPCz were prepared to study the effect of substitution positions of tetraphenylsilyl and carbazole on the device performances, and the 2CzBTP and 2mSiBTP were synthesized as reference materials. In the device application, the four hosts were used as electron transport type hosts mixed with a hole transport type 3,3'-di(9<i>H</i>-carbazol-9-yl)-1,1'-biphenyl (mCBP) host in the mixed host. Among the four mixed hosts, the mCBP/CzBTPmSi mixed host showed an external quantum efficiency of 23.9% and a device lifetime over 4000 h at 100 cd m<sup>-2</sup> in the blue phosphorescent organic light-emitting diodes.
A Novel Spectrum Sensing Scheme Based On Periodicity Of Dvb-T Pilot Signals (2010)

This paper proposes a novel spectrum sensing technique for the digital video broadcasting-terrestrial (DVB-T) systems, which utilizes the periodicity of pilot signals in the orthogonal frequency division multiplexing (OFDM) symbols. The proposed scheme can overcome the effect of the timing synchronization error by recorrelating the correlation values in the same sample distances. The numerical results demonstrate that the detection probability performance of the proposed scheme outperforms that of the conventional scheme when there exists a timing synchronization error.
Detection of singlet oxygen luminescence for experimental corneal rose bengal photodynamic antimicrobial therapy (2020)

Rose bengal photodynamic antimicrobial therapy (RB-PDAT) treats corneal infection by activating rose bengal (RB) with green light to produce singlet oxygen (<sup>1</sup>O<sub>2</sub>). Singlet oxygen dosimetry can help optimize treatment parameters. We present a <sup>1</sup>O<sub>2</sub> dosimeter for detection of <sup>1</sup>O<sub>2</sub> generated during experimental RB-PDAT. The system uses a 520 nm laser and an InGaAs photoreceiver with bandpass filters to detect <sup>1</sup>O<sub>2</sub> luminescence during irradiation. The system was validated in RB solutions and <i>ex vivo</i> in human donor eyes. The results demonstrate the feasibility of <sup>1</sup>O<sub>2</sub> dosimetry in an experimental model of RB-PDAT in the cornea.
Specimen‐induced distortions in light microscopy (2007)

Specimen-induced aberrations affect the imaging properties in optical 3D microscopy, especially when high numerical aperture lenses are used. Studies on aberrations are often properly concerned with the degradation of image quality such as compromised resolution or reduced signal intensity. Apart from these, aberration effects can also introduce geometric image distortions. The effects, discussed here are particularly strong when thick biological specimens are investigated. Using a high numerical aperture interferometer, we measured wavefront aberrations in transmission mode and quantified geometric distortions associated with specimen-induced aberrations. This assessment for a range of biological specimens allows estimation of the accuracy of spatial measurements. The results show that high-resolution spatial measurements can be significantly compromised by specimen-induced aberrations.
Erratum: Correlation of clinical and immunological data in a metastatic melanoma patient with heterogeneous tumor responses to ipilimumab therapy (2010)

In Cancer Immunity, Vol. 10, p. 1 (7 January 2010), an author name was missing from the final manuscript. Erika Ritter, of the Ludwig Institute for Cancer Research, is an author on this paper. The correct author list is as follows: Jianda Yuan, David B. Page, Geoffrey Y. Ku, Yanyun Li, Zhenyu Mu, Charlotte Ariyan, Humilidad F. Gallardo, Ruth-Ann Roman, Agnes I. Heine, Stephanie L. Terzulli, Erika Ritter, Sacha Gnjatic, Gerd Ritter, Achim A. Jungbluth, James P. Allison, Lloyd J. Old and Jedd D. Wolchok.
Quantifying the Predictive Performance of Objectively Measured Physical Activity on Mortality in the UK Biobank (2020)

Objective measures of PA derived from accelerometry outperform traditional predictors of all-cause mortality in the UK Biobank except age and substantially improve the prediction performance of mortality models based on traditional risk factors. Results confirm and complement previous findings in the National Health and Nutrition Examination Survey (NHANES).
Autonomic mix-aware provisioning for non-stationary data center workloads (2010)

Online Internet applications see dynamic workloads that fluctuate over multiple time scales. This paper argues that the non-stationarity in Internet application workloads, which causes the request mix to change over time, can have a significant impact on the overall processing demands imposed on data center servers. We propose a novel mix-aware dynamic provisioning technique that handles both the non-stationarity in the workload as well as changes in request volumes when allocating server capacity in Internet data centers. Our technique employs the k-means clustering algorithm to automatically determine the workload mix and a queuing model to predict the server capacity for a given workload mix. We implement a prototype provisioning system that incorporates our technique and experimentally evaluate its efficacy on a laboratory Linux data center running the TPC-W web benchmark. Our results show that our k-means clustering technique accurately captures workload mix changes in Internet applications. We also demonstrate that mix-aware dynamic provisioning eliminates SLA violations due to under-provisioning with non-stationary web workloads, and that it offers a better resource usage by reducing over-provisioning when compared to a baseline provisioning approach that only reacts to workload volume changes. We also present a case study of our provisioning approach on Amazon's EC2 cloud platform.