gebhart/patrepeval huggingface dataset:
Measurement and characterization of nanosecond laser driven shockwaves utilizing photon Doppler velocimetry (2021)

Laser driven shockwaves from nanosecond pulsed lasers were evaluated for pressure magnitude and duration using photon Doppler velocimetry (PDV). Specific investigations were performed on Ti-6Al-4V alloys and 7085-T7651 aluminum alloys with laser full-width half-max pulse lengths ranging from 6 to 20 ns and laser intensities of 2–10 GW/cm2. The rear surface velocity data obtained using a heterodyne PDV system and an automated signal processing algorithm are demonstrated and utilized to capture rear surface velocity profiles. Peak shockwave pressures measured under bare surface water confinement reached approximately 6 GPa. Shockwave loading durations were observed to correspond with laser pulse durations with impulse loading times on the order of 2×–4× the laser pulse duration.
Supplementary Table 5 from PRMT1-Mediated Translation Regulation Is a Crucial Vulnerability of Cancer (2023)

&lt;p&gt;GSEA analysis of gene dependencies that correlate with Prmt1 dependency in the human Project Achilles dataset.&lt;/p&gt;
Angiopoietin-1 Protects Against the Development of Cardiac Allograft Arteriosclerosis (2003)

Our findings suggest that the antiinflammatory properties of Ang1 may offer an entirely new therapeutic approach to prevent cardiac allograft arteriosclerosis.
Photonic crystal cavity-assisted upconversion infrared photodetector (2015)

We describe an upconversion infrared photodetector assisted by a gallium phosphide photonic crystal nanocavity directly coupled to a silicon photodiode. The strongly cavity-enhanced second harmonic signal radiating from the gallium phosphide membrane can thus be efficiently collected by the silicon photodiode, which promises a high photoresponsivity of the upconversion detector as 0.81 A/W with the coupled power of 1W. The integrated upconversion photodetector also functions as a compact autocorrelator with sub-ps resolution for measuring pulse width and chirp.
Mitigation of Bandwidth Limitation in Wireless Doherty Amplifiers With Substantial Bandwidth Enhancement Using Digital Techniques (2012)

This paper proposes a new method for extending the bandwidth of Doherty power amplifiers (PAs) in the digital domain. The bandwidth enhancement is achieved through a frequency-selective pre-compensation mechanism that is derived to prevent the efficiency degradation that naturally occurs as the frequency of operation deviates from the center frequency. A methodical analysis of the frequency response of the conventional Doherty PA and that of the proposed Doherty PA is carried out to point out the limitations of the former and demonstrate the capability of the latter in recovering the bandwidth. Over the frequency range spanning from 1.96 to 2.46 GHz, the measured drain efficiency at 6-7-dB output power back-off is higher than 40% for the proposed Doherty PA. Such efficiency performance is achievable only from 2.04 to 2.22 GHz using the conventional Doherty PA. Hence, the bandwidth is enhanced from 180 to 500 MHz, which corresponds to an increase by a factor of 2.8 (i.e., almost triple). By applying the proposed methodology, a Doherty PA that is originally designed at the center frequency of 2.14 GHz for downlink wideband code division multiple access became operative at 1.98-GHz uplink wideband code division multiple access (UL-WCDMA), 2.22-GHz long-term evolution (LTE), and 2.34-GHz worldwide interoperability for microwave access (WiMAX) bands. The average drain efficiencies for UL-WCDMA, LTE, and WiMAX applications, were 40.1%, 44.2%, and 41.4%, respectively, using the proposed Doherty PA, and 37%, 37.3%, and 35.2%, respectively, using the conventional Doherty PA.
Using Multi-Resolution Feature Maps with Convolutional Neural Networks for Anti-Spoofing in ASV (2020)

This paper presents a simple but effective method that uses multi-resolution feature maps with convolutional neural networks (CNNs) for anti-spoofing in automatic speaker verification (ASV). The central idea is to alleviate the problem that the feature maps commonly used in anti-spoofing networks are insufficient for building discriminative representations of audio segments, as they are often extracted by a single-length sliding window. Resulting trade-offs between time and frequency resolutions restrict the information in single spectrograms. The proposed method improves both frequency resolution and time resolution by stacking multiple spectrograms that are extracted using different window lengths. These are fed into a convolutional neural network in the form of multiple channels, making it possible to extract more information from input signals while only marginally increasing computational costs. The efficiency of the proposed method has been conformed on the ASVspoof 2019 database. We show that the use of the proposed multiresolution inputs consistently outperforms that of score fusion across different CNN architectures. Moreover, computational cost remains small.
Linear and nonlinear Fano resonance on two-dimensional magnetic metamaterials (2011)

We demonstrate that both linear and nonlinear Fano resonances can be realized on two dimensional magnetic metamaterials. The Fano resonance comes from the interference between localized magnetic plasmon resonance and propagating surface plasmon polaritons. When studying the linear optical response of the metamaterial structure, this interference phenomenon was observed in the ellipsometric spectrum. By finely tailoring the geometrical parameters of the magnetic metamaterial device, the nonlinear Fano response was tuned to a near-infrared wavelength (1.61--1.8 \ensuremath{\mu}m) of femtosecond pump laser, and Fano-type modulation of the third harmonic generation was found and agrees well with our theoretical model.
Ovatodiolide and antrocin synergistically inhibit the stemness and metastatic potential of hepatocellular carcinoma via impairing ribosome biogenesis and modulating ERK/Akt-mTOR signaling axis (2022)

Activation of mitogen-activated protein kinase (MAPK) and PI3K signaling confers resistance against sorafenib, a mainstay treatment for advanced hepatocellular carcinoma (HCC). Antrocin and ovatodiolide constitute as the most potent secondary metabolites isolated from Antrodia camphorata and Anisomeles indica, respectively. Both natural compounds have recently gained a lot of attention due to their putative inhibition of MAPK and PI3K signaling in various solid cancers. However, whether their combination is effective in HCC remains unknown. Here, we investigated their effect, alone or in various combinations, on MAPK and PI3K signaling pathways in HCC cells. An array of in vitro study were used to investigate anticancer and stemness effects to treat HCC, such as cytotoxicity, drug combination index, migration, invasion, colony formation, and tumor sphere formation. Drug effect in vivo was evaluated using mouse xenograft models. In this study, antrocin and ovatodiolide synergistically inhibited the SNU387, Hep3B, Mahlavu, and Huh7 cell lines. Sequential combination treatment of Huh7 and Mahlavu with ovatodiolide followed by antrocin resulted stronger cytotoxic effect than did treatment with antrocin followed by ovatodiolide, their simultaneous administration, antrocin alone, or ovatodiolide alone. In the Huh7 and Mahlavu cell lines, ovatodiolide→antrocin significantly suppressed colony formation and proliferation as well as markedly downregulated ERK1/2, Akt, and mTOR expression. Inhibition of ERK1/2 and Akt/mTOR signaling by ovatodiolide→antrocin suppressed ribosomal biogenesis, autophagy, and cancer stem cell-like phenotypes and promoted apoptosis in Huh7 and Mahlavu cells. The sorafenib-resistant clone of Huh7 was effectively inhibited by synergistic combination of both compound in vitro. Eventually, the ovatodiolide→antrocin combination synergistically suppressed the growth of HCC xenografts. Taken together, our findings suggested that ovatodiolide→antrocin combination may represent potential therapeutic approach for patients with advanced HCC.
X-Ray Investigations and Determination of the Dielectric Properties of the Compound Ba4.5Gd9Ti18O54 (1996)

The composition of the Gd variant of the Ba 6- x R 8+2/3 x Ti 18 O 54 family of solid solutions ( R=rare earth) was determined by investigating its high temperature phase relations and by wavelength-dispersion spectroscopic analysis. The composition of the compound was determined to be Ba 4.5 Gd 9 Ti 18 O 54 , which corresponds to x =1.5 without a detectable solid solubility range. The intensities of the diffraction lines are not in accordance with published values in the powder diffraction file (No. 43–233). An investigation of the thermal stability revealed that Ba 4.5 Gd 9 Ti 18 O 54 starts to decompose at a temperature around 1350° C. It decomposes into a Gd 2 Ti 2 O 7 , BaTi 2 O 5 solid solution with Gd 2 O 3 , and probably Ba 4 Ti 13 O 30 . However, during slowly cooling metastable BaTi 2 O 5 (ss) also decomposes into Ba 6 Ti 17 O 40 and BaTiO 3 solid solution with Gd 2 O 3 . Single phase Ba 4.5 Gd 9 Ti 18 O 54 ceramics displayed a dielectric constant ( ε r ) of 76.1, a Q x f -value of 2050 and a temperature coefficient of the resonant frequency (τ f ) of -35 ppm/K.
Quantitative Analysis of <i>Radix Rehmanniae</i> from Genuine Producing Area by Near Infrared Spectroscopy (2014)

In this paper the water extract of Radix Rehmanniae from genuine producing area was rapidly determined by near-infrared spectroscopy (NIRS). The quantitative analysis model of the water extraction of Radix Rehmanniae was established by Partial Least Square (PLS). The correlation coefficient of calibration (R 2 ) was 0.99529; the root-mean-square error of prediction (RMSEP) was 0.134. The results indicated that the water-soluble components in Radix Rehmanniae from genuine producing area can be rapidly and accurately determined by near-infrared spectroscopy technology.
A three-legged MATLAB/SIMULINK transformer model using a fictitious delta winding (2016)

This paper proposes a simple MATLAB/ SIMULINK model of a three-phase, three-legged, saturated transformer. A fictitious delta winding is added to three single-phase saturable transformers. The proposed model is simple and fairly accurate to model the nonlinear characteristics of a saturable three-legged transformer including mutual coupling.
Transducer placement for robustness to variations in boundary conditions for active structural acoustic control (2003)

The study of control strategies aimed at the reduction of turbulent boundary layer noise transmission into the fuselage of an aircraft has been a topic of academic and industrial research for several years. In this work we focus on an approach that will attempt to address a practical application issue: the impact of uncertainty in boundary conditions on the choice of actuator and sensor locations for structural acoustic control. The selection of an optimized set of transducers and the creation of a suitably adjustable test system is used to demonstrate that robustness to bounded variations in boundary conditions of a plate is achievable in active structural acoustic control. This robustness is achieved through the optimization of transducer placement with respect to maximizing control of structural acoustic radiation over the desired range of boundary conditions. This project incorporates energy based modeling of the structure, electromechanical piezo coupling, radiation filter modeling, and control analysis through the use of Hankel Singular Value (HSV) estimates and optimization based upon the genetic algorithm. Testing in a transmission loss facility will be used to validate the selected transducer placements and demonstrate a reduction in radiated sound power. [Work supported by NASA.]
Determination of Compositional, Configurational Sequences in High Conversion Methyl Methacrylate-Methacrylic Acid Emulsion Copolymers Using a Rapid and Selective Counting Procedure (1983)

Abstract High conversion methyl methacrylate (MMA)-methacrylic acid (MA) copolymers prepared by two different emulsion polymerization processes were characterized in terms of composition and sequence distribution by 1H- and 13C-NMR, taking into account the conversion effect. A rapid and selective counting procedure for calculating the compositional configurational pentads (512 values) in these copolymers is described. From this counting procedure and using the Klesper's assignment of the 18 peaks observed in the 13C-NMR carbonyl resonance spectrum of the copolymers, a relatively good agreement was found between the calculated and experimental fractions of each peak intensity. Moreover, this study allows differences in compositional homogeneity to be characterized as a function of the nature of the emulsion polymerization process.
Giant axonal neuropathy: normal protein composition of neurofilaments. (1983)

A 14-year-old boy had progressive weakness and ataxia since two years of age with tightly curled hair, facial diplegia, distal weakness and hypaesthesia, cerebellar syndrome and normal intelligence. He also had distal renal tubular acidosis manifested by metabolic acidosis. Sural nerve ultrastructure showed numerous giant axons packed with neurofilaments. The neurofilament major proteins of 68 000, 160 000 and 210 000 daltons found in normal sural nerve were also present in the diseased nerve indicating that the protein composition of neurofilaments which accumulates in this disorder has not been appreciably altered. The amount of 68 000 dalton neurofilament protein was two times higher in giant axonal neuropathy nerve than in the control nerve. Our results suggest that the neurofibrillary pathology in giant axonal neuropathy is due to a build-up of normal neurofilaments.
MAGNETISM, DIMENSIONAL CHANGES, AND MAGNETIC TRANSITIONS IN HYDRATED CESIUM MANGANESE CHLORIDE (1972)

Dimensional changes (strain) along the three principal crystal axes of the antiferromagnet CsMnCl3-2H2O are studied as a function of magnetic field and temperature in the antiferromagnetic, spin flopped, and paramagnetic phases. Changes in dimensions through the phase transitions between the magnetic states are examined. By applying the molecular field model and utilizing all available information, magnetic properties of CsMnCl3-2H2O are determined. The possible usefulness of this material in a magnetic refrigeration cycle is evaluated.
Hybrid organogels and aerogels from co-assembly of structurally different low molecular weight gelators (2013)

The blending of perfluorinated bile ester derivatives with the gelator 2,3-didecyloxyanthracene (DDOA) yields a new class of hybrid organo- and aerogels displaying a combination of optical and mechanical properties that differ from those of pure gels. Indeed, the nanofibers constituting the hybrid organogels emit polarized blue light and display dichroic near-UV absorption via the achiral DDOA molecules, thanks to their association with a chiral bile ester. Moreover, the thermal stability and the mechanical yield stress of the mixed organogels in DMSO are enhanced for blends of DDOA with the deoxycholic gelator (DC11) having a C11 chain, as compared to the pure components' gels. When the chain length of the ester is increased to C13 (DC13) a novel compound for aerogel formation directly in scCO2 is obtained under the studied conditions. A mixture of this compound with DDOA is also able to gelate scCO2 leading to novel composite aerogel materials. As revealed by SAXS measurements, the hybrid and the pure DDOA and DC13 aerogels display cell parameters that are very similar. These SAXS experiments suggest that crystallographic conditions are very favorable for the growth of hybrid molecular arrangements in which DDOA and DC13 units could be interchanged. Specific molecular interactions between two components are not always a pre-requisite condition for the formation of a hybrid nanostructured material in which the components mutually induce properties.
Comparison of the cardiotoxic effects of liposomal doxorubicin (TLC D-99) versus free doxorubicin in beagle dogs. (1993)

The cardiotoxic potential of liposome encapsulated doxorubicin (TLC D-99) prepared by a remote-loading technique was compared with that of free doxorubicin (1.5mg/kg administered every 3 weeks for 8 cycles) in beagle dogs. Both agents were equally myelosuppressive, and all dogs completed both treatments. There were no deaths during the study. Experimental animals were killed between 157 and 164 days after the start of the trial. All of the dogs (n = 6) that received free doxorubicin had either moderate (1 animal) or severe (5 animals) vacuolization of myocardial tissue. None of the dogs treated with liposomal doxorubicin had lesions suggestive of cardiomyopathy. Administration of free doxorubicin was associated with transient anorexia, reduced weight gain, alopecia, and gastrointestinal toxicity. Such adverse reactions were either much less severe or absent in animals that received liposomal doxorubicin. The results of this study demonstrate that TLC D-99 significantly decreases both the myocardial toxicity and other adverse reactions of this potent antineoplastic drug. TLC D-99 is now in Phase II clinical trials.
Low-temperature Pd direct bonding and electrical transport across InP-Pd-GaAs interfaces (2002)

We have developed a low-temperature Pd bonding to integrate InP material with the GaAs substrate. The solid state reactions of Pd with both InP and GaAs allows Pd to be used as a sandwiched ohmic contact between two dissimilar materials. The InP-Pd-GaAs interfaces have been characterized by scanning electron microscopy, optical reflectance, and electrical transport.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
An antibody specific for interleukin‐6 reverses age‐associated changes in spontaneous and induced cytokine production in mice (1997)

A number of quantitative and qualitative changes in the pattern of cytokine production have been reported to accompany the process of ageing in laboratory animals and in human populations, including an increase in serum levels of interleukin-1 (IL-1) and IL-6, as well as increased concanavalin A (ConA)-stimulated production of IL-4, IL-10 and transforming growth factor-beta (TGF-beta), and decreased production of IL-2 from cultured spleen cells. Increased IL-1 and IL-6 production is a feature of splenic adherent cells and peritoneal exudate cells taken from aged mice and stimulated with lipopolysaccharide in vitro. We have asked whether the altered production of lymphocyte-derived cytokines (IL-4, IL-2, TGF-beta) is itself a function of a primary alteration in IL-1/IL-6 production (from macrophage/monocytes) by infusing monoclonal antibodies to these cytokines prior to harvesting cells from aged mice and stimulating the cells in vitro. Anti-IL-6, but not anti-IL-1, reversed the age-associated alteration in lymphocyte cytokine production. The general pattern of cytokine production in aged mice is of a type-2 cytokine type, and thus these data are consistent with the idea that increased production of IL-6 in aged animals is causally implicated in this age-associated polarization to type-2 cytokine production.
Computational and experimental analysis of TMS-induced electric field vectors critical to neuronal activation (2015)

These results provide critical new understanding of the factors by which TMS induces cortical activation necessary for predictive and repeatable use of this noninvasive stimulation modality.
Laser Processing of Metal Oxides: Laser Irradiation of Metal Oxide Films and Nanostructures: Applications and Advances (Adv. Mater. 14/2018) (2018)

Laser irradiation has been utilized to induce modification of phase structure (amorphous/crystalline), and microstructure (crystallinity, grain growth, and defects) of metal oxides in order to tailor their properties and to improve their functionality for applications in dielectric, ferroelectric, and piezoelectric systems, multiferroic magnetoelectrics, photocatalysis, gas sensors, transparent conductors, field-effect transistors, solar cells, and thermistors. This technique is reviewed by Shashank Priya, Keon Jae Lee, Jungho Ryu, and co-workers in article number 1705148.
Ultrasound Monitoring of RBC Aggregation as a Real-Time Marker of the Inflammatory Response in a Cardiopulmonary Bypass Swine Model* (2013)

Continuous RBC aggregation monitoring can characterize the evolving inflammatory response during and after cardiopulmonary bypass. The Structure Factor Size and Attenuation Estimator is proposed as a real-time noninvasive monitoring technique to anticipate inflammation-related complications during high-risk surgery or critical care situations. Because RBC aggregation promotes vascular resistance and thrombosis, W could also provide early information on vascular disorders in those clinical situations.
Novel On-Chip Antenna Structures and Frequency Selective Surface (FSS) Approaches for Millimeter Wave Devices (2007)

This paper presents novel on-chip antenna structures and provides new on-chip circuit concepts that may be implemented as part of standard integrated circuit fabrication processes for wireless integrated circuits of the future. As wavelengths of wireless local area networks (WLANs) and personal area networks (PANs) shrink to millimeter lengths at 60 GHz and above, interconnectivity issues and cost/scale requirements will require these new approaches for built-in on- chip antennas. This paper highlights advancements in both the integrated circuits and microwave technology research communities, and presents a number of promising areas of research. Finally, we describe an experimental probe station that has been developed at The University of Texas for the testing and characterization of novel on-chip antennas and distributed components.
Lettuce endosperm weakening: a role for endo-beta-mannanase in seed germination at high temperature. (2009)

Under high temperatures, seed germination of most lettuce genotypes can be erratic or completely inhibited. Weakening of the endosperm layer is a prerequisite to radicle protrusion at high temperatures. Enzyme-mediated degradation of endosperm cell walls may be a crucial factor for lettuce germination at high temperatures. The galactomannan polysaccharides in lettuce endosperm cell wall are mobilized by endo-β-mannanase. The involvement of endo-β-mannanase during germination of lettuce seeds at high temperature (35°C) was investigated by gel-diffusion assay. Genotype, seed maturation temperature, and seed priming enhanced lettuce seed germination at high temperature. Less force to penetrate the endosperm was required by seeds of thermotolerant genotypes or primed seeds, and structural alterations of endosperm in the micropylar area were also observed before radicle protrusion. Higher endo-β-mannanase activity in lettuce endosperm before radicle protrusion was verified in these situations. Moreover, at high temperature, thermotolerant genotypes produced more ethylene, more endo-β-mannanase, and germinated better than thermosensitive genotypes. An inhibitor of ethylene action, silver thiosulfate, inhibited both mannanase activity and germination. A precursor of ethylene, ACC, induced endo-β-mannanase activity and germination of thermosensitive cv. Dark Green Boston at 35°C. These results suggest that increased endo-β-mannanase activity might contribute to lettuce endosperm weakening, especially at high temperatures.