gebhart/patrepeval huggingface dataset:
A Simple Calibration Procedure for an LPIT plus PMU System Under Off-Nominal Conditions (2019)

This work deals with two paramount devices when Smart Grids are concerned: phasor measurement units (PMUs) and low-power instrument transformers (LPITs). In particular, a simple calibration procedure to test the measurement chain PMU + LPIT has been developed. The procedure involves steady-state conditions of the grid and off-nominal input signals for testing current, voltage, frequency, and rate of change of frequency (ROCOF). In addition, the procedure includes a preliminary testing of the PMU without the LPIT to understand the influence of the latter. The procedure is then applied to a specific case study: a low-cost PMU developed by the authors and one of the most common LPITs adopted in Italian medium voltage networks. The obtained results are promising for two reasons. First, the low-cost PMU works correctly even in off-nominal conditions of the grid; second, the presented calibration procedure demonstrated to be effective and applicable to very common equipment, using a rather simple test setup.
Surface Plasmon Resonances Effects on Different Patterns of Solid-silver and Silver-shell Nanocylindrical Pairs (2010)

Abstract Surface plasmon resonances effects on various geometries of solid-silver and silver-shell nanocylindrical pairs that interact with incident plane wave of transverse magnetic polarization are simulated by using the finite element method. Results show that the silver-shell nanocylindrical pair exhibits tunable plasmon resonances in the near-field zone that are not observed for the solid-silver case of similar size. It is also found that the facing corners of nanocylindrical pairs induce more surface plasmons in a wider range of wavelength.
ChemInform Abstract: Synthesis and Characterization of Compounds with a Group 12‐Arsenic Bond. Crystal Structure of (tBuZnAs(tBu)2)2. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Inducible interleukin-1 gene expression in human vascular smooth muscle cells. (1986)

Interleukin-1 (IL-1) mediates many components of generalized host response to injury and may also contribute to local vascular pathology during immune or inflammatory responses. Because altered function of smooth muscle cells (SMC) accompanies certain vascular diseases, we tested whether SMC themselves might produce this hormone. Unstimulated SMC contain little or no IL-1 mRNA. However, exposure to bacterial endotoxin caused accumulation of IL-1 mRNA in SMC cultured from human vessels. Endotoxin maximally increased IL-1 beta mRNA in SMC after 4-6 h. The lowest effective concentration of endotoxin was 10 pg/ml. 10 ng/ml produced maximal increases in IL-1 beta mRNA. Interleukin-1 alpha mRNA was detected when SMC were incubated with endotoxin under "superinduction" conditions with cycloheximide. Endotoxin-stimulated SMC also released biologically functional IL-1, measured as thymocyte costimulation activity inhibitable by anti-IL-1 antibody. Thus, human SMC can express IL-1 beta and IL-1 alpha genes, or very similar ones, and secrete biologically active product in response to a pathological stimulus. Endogenous local production of this inflammatory mediator by the blood vessel wall's major cell type could play an important early role in the pathogenesis of vasculitis and arteriosclerosis.
Using an adaptive and time predictable runtime system for power-aware HPC-oriented applications (2016)

An increasing number of High-Performance Applications demand some form of time predictability, in particular in scenarios where correctness depends on both performance and timing requirements, and the failure to meet either of them is critical. Consequently, a more predictable HPC system is required, particularly for an emerging class of adaptive real-time HPC applications. Here we present our runtime approach which produces the results in the predictable time with the minimized allocation of hardware resources. The paper describes the advantages in terms of execution time reliability and the trade-offs regarding power/energy consumption and temperature of the system compared with the current GNU/Linux governors.
Radiogenomics is the future of treatment response assessment in clinical oncology (2018)

Dr. El-Naqa and Dr. Napel have no relevant conflicts of interest.
Determination of the effective diffusion constant of I/sub 3//sup -/ ions in nanoporous TiO/sub 2/ networks (2003)

A device structure similar to the dye sensitized solar cells is investigated by current/voltage measurements. Using a platinum front electrode directly in contact to the nanoporous TiO/sub 2/ layer, we find diffusion limitation due to triiodide I/sub 3//sup -/. From the value of the maximum current density we calculate the I/sub 3//sup -/ diffusion constant D/sub T/ in a nanoporous medium. In addition, we evaluate a quantitative model to describe the complete I/V-characteristic of the device. Fitting the model to the experimental data we deduce a diffusion constant for I/sub 3//sup -/ of D/sub T/ = 1.24 (/spl plusmn/ 0.02)/spl times/10/sup -5/ cm/sup 2/s/sup -1/ in the bulk of the electrolyte and an effective diffusion constant of D/sub T//sup eff/ = 0.44 (/spl plusmn/ 0.02)/spl times/10/sup -5/ cm/sup 2/s/sup -1/ within the pores of the TiO/sub 2/ network.
Long-lasting multifunctional CD8+T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination (2015)

Cytotoxic T cells are considered crucial for antitumor immunity and their induction is the aim of various immunotherapeutic strategies. High frequencies of tumor-specific CD8<sup>+</sup> T cells alone, however, are no guarantee for long-term tumor control. Here, we analyzed the functionality of tumor-specific CD8<sup>+</sup> T cells in melanoma patients upon dendritic cell vaccination by measuring multiple T cell effector functions considered crucial for anticancer immunity, including the expression of pro-inflammatory cytokines, chemokines and cytotoxic markers (IFNγ, TNFα, IL-2, CCL4, CD107a). We identified small numbers of multifunctional (polyfunctional) tumor-specific CD8<sup>+</sup> T cells in several patients and dendritic cell therapy was able to improve the functionality of these pre-existing tumor-specific CD8<sup>+</sup> T cells. Generated multifunctional CD8<sup>+</sup> T cell responses could persist for up to ten years and within the same patient functionality could vary greatly for the different vaccination antigens. Importantly, after one cycle of DC vaccination highly functional CD8<sup>+</sup> T cells were only detected in patients displaying prolonged overall survival. Our results shed light on the dynamics of multifunctional tumor-specific CD8<sup>+</sup> T cells during metastatic melanoma and reveal a new feature of dendritic cell vaccination <i>in vivo</i>.
Transition metal interaction and Ni-Fe-Cu-Si phases in silicon (2007)

In the present article we characterize several intermetallic phases of the Cu-Ni-Fe-Si system found as precipitates in the misfit dislocation layer of intentionally contaminated and slowly cooled Si1−xGex∕Si-heterostructures. The clusters showed a characteristic phase speciation into a Cu-rich part similar to Cu3Si and an Fe-Ni-Cu-Si phase similar to NiSi2. It is suggested that the precipitate formation of the investigated intermetallic silicides involves a homogeneous precursor phase at higher temperatures that later decomposes into the observed phases. Our results indicate that chemical reactions between metals and silicon during precipitation may reduce the lattice mismatch compared to single-metal precipitates, rendering mixed-metal-silicide precipitates more stable and energetically favorable.
Functional photoacoustic microscopy in vivo (2006)

Functional photoacoustic microscopy is a hybrid imaging technique that detects laser induced photoacoustic waves to image biological tissues in three dimensions. Its imaging depth exceeds the fundamental depth limit of the existing high resolution optical imaging modalities while maintaining a comparable ratio of imaging depth to axial resolution. The amplitude of photoacoutic waves is related to tissue's optical absorption and, therefore, functional imaging can be achieved by acquiring spectroscopic information. We demonstrate here the capabilities of functional photoacoustic microscopy by volumetric imaging a skin melanoma tumor and functional imaging of hemoglobin oxygen saturation in single vessels <i>in vivo</i>.
Data from Targeting RET Kinase in Neuroendocrine Prostate Cancer (2023)

&lt;div&gt;Abstract&lt;p&gt;The increased treatment of metastatic castration-resistant prostate cancer (mCRPC) with second-generation antiandrogen therapies (ADT) has coincided with a greater incidence of lethal, aggressive variant prostate cancer (AVPC) tumors that have lost dependence on androgen receptor (AR) signaling. These AR-independent tumors may also transdifferentiate to express neuroendocrine lineage markers and are termed neuroendocrine prostate cancer (NEPC). Recent evidence suggests kinase signaling may be an important driver of NEPC. To identify targetable kinases in NEPC, we performed global phosphoproteomics comparing several AR-independent to AR-dependent prostate cancer cell lines and identified multiple altered signaling pathways, including enrichment of RET kinase activity in the AR-independent cell lines. Clinical NEPC patient samples and NEPC patient-derived xenografts displayed upregulated RET transcript and RET pathway activity. Genetic knockdown or pharmacologic inhibition of RET kinase in multiple mouse and human models of NEPC dramatically reduced tumor growth and decreased cell viability. Our results suggest that targeting RET in NEPC tumors with high RET expression could be an effective treatment option. Currently, there are limited treatment options for patients with aggressive neuroendocrine prostate cancer and none are curative.&lt;/p&gt;Implications:&lt;p&gt;Identification of aberrantly expressed RET kinase as a driver of tumor growth in multiple models of NEPC provides a significant rationale for testing the clinical application of RET inhibitors in patients with AVPC.&lt;/p&gt;&lt;/div&gt;
Systems description of measurement and reconstruction of microgrid polarimeters (2011)

In a recent paper we developed a formal theory of demodulation for polarimeters with arbitrary modulation schemes. This theory provides a framework for artifact free reconstruction of polarimetric data provided a band limited scene. Here we apply that theory to three different configurations of 2-D spatially modulated microgrids.
Optimization of waterspace management and scheduling for multiple unmanned vehicles (2020)

We describe an approach for accomplishing the high-level mission planning required for a heterogeneous team of autonomous vehicles performing surveys in multiple areas, such as required for mine countermeasure (MCM) missions. The high-level mission scheduling and waterspace management require sequencing the order and location of lower-level tasks to be completed by each vehicle in the heterogeneous team: unmanned surface vessels (USVs) and unmanned underwater vehicles (UUVs). In this context, the USVs serve as transport vehicles while the UUVs perform the actual surveys and execute any other local actions. We develop a solution to this complex sequencing operation by leveraging unique information processing, communication, refueling, and planning windows that form constraints within the system within a formal scheduling optimization framework. We use mixed-integer linear programming (MILP) as a solution method for the associated optimization problem. By using such a standard optimization approach, we both take advantage of optimality guarantees on the solution and extensive commercial numerical solvers. In addition to developing the numerical optimization problem, we also include methods to account for risks due to schedule slip for the individual tasks. We conclude with an example of joint USV/UUV planning using the optimization algorithm
An Engineered Synthetic Receptor–Aptamer Pair for an Artificial Signal Transduction System (2023)

Cell membrane receptors regulate cellular responses through sensing extracellular environmental signals and subsequently transducing them. Receptor engineering provides a means of directing cells to react to a designated external cue and exert programmed functions. However, rational design and precise modulation of receptor signaling activity remain challenging. Here, we report an aptamer-based signal transduction system and its applications in controlling and customizing the functions of engineered receptors. A previously reported membrane receptor-aptamer pair was used to design a synthetic receptor system that transduces cell signaling depending on exogenous aptamer input. To eliminate the cross-reactivity of the receptor with its native ligand, the extracellular domain of the receptor was engineered to ensure that the receptor was solely activated by the DNA aptamer. The present system features tunability in the signaling output level using aptamer ligands with different receptor dimerization propensities. In addition, the functional programmability of DNA aptamers enables the modular sensing of extracellular molecules without the need for genetic engineering of the receptor.
An Alpha Particle Distribution Function for Mirror Loss-Cone Type Instability Calculations (1986)

The modeling of the steady-state fusion-born alpha particle distribution in a mirror loss-cone is investigated. The Legendre function expansion and diffusion-front methods are reviewed and examined. The diffusion-front method is shown to be an accurate and efficient method for alpha-loss-cone instability calculations in a tandem mirror fusion device.
Germanium-on-silicon planar concave grating wavelength (de)multiplexers in the mid-infrared (2013)

Mid-infrared wavelength (de)multiplexers based on planar concave gratings (PCGs) fabricated on a germanium-on-silicon waveguide platform are presented. PCGs with two different types of gratings (flat facet and distributed bragg reflectors) are analyzed for both transverse electric (TE) and transverse magnetic (TM) polarizations. The insertion loss and cross talk for flat facet PCGs are found to be −7.6/−6.4 dB and 27/21 dB for TE/TM polarization. For distributed bragg reflector PCGs the insertion loss and cross talk are found to be −4.9/−4.2 dB and 22/23 dB for TE/TM polarization.
Psychosocial interventions for the maintenance of weight loss in obese adults (2015)

This protocol was withdrawn because finishing the project within adequate deadlines could not be achieved.
Supplementary Figure Legends from C-RAF Mutations Confer Resistance to RAF Inhibitors (2023)

&lt;p&gt;Supplementary Figure Legends - PDF file 92K, Supplementary figure legends&lt;/p&gt;
The reliability of dynamic interfaces in LIGA microsystems. (2003)

The Model With Internal Restrictions on Item Difficulty (MIRID; Butter, 1994) has been useful for investigating cognitive behavior in terms of the processes that lead to that behavior. The main objective of the MIRID model is to enable one to test how component processes influence the complex cognitive behavior in terms of the item parameters. The original MIRID model is, indeed, a fairly restricted model for a number of reasons. One of these restrictions is that the model treats items as fixed and does not fit measurement contexts where the concept of the random items is needed. In this article, random item approaches to the MIRID model are proposed, and both simulation and empirical studies to test and illustrate the random item MIRID models are conducted. The simulation and empirical studies show that the random item MIRID models provide more accurate estimates when substantial random errors exist, and thus these models may be more beneficial.
Partial proteolysis of human l-type phosphofructokinase (1981)

Conference Abstract| April 01 1981 Partial proteolysis of human l-type phosphofructokinase M. C. MEIENHOFER; M. C. MEIENHOFER 1Institut de Pathologie Moléculaire, 75674 PARIS CEDEX 14 - FRANCE Search for other works by this author on: This Site PubMed Google Scholar J. L. LAGRANGE; J. L. LAGRANGE 1Institut de Pathologie Moléculaire, 75674 PARIS CEDEX 14 - FRANCE Search for other works by this author on: This Site PubMed Google Scholar A. KAHN A. KAHN 1Institut de Pathologie Moléculaire, 75674 PARIS CEDEX 14 - FRANCE Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1981) 9 (2): 358P. https://doi.org/10.1042/bst009358p Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation M. C. MEIENHOFER, J. L. LAGRANGE, A. KAHN; Partial proteolysis of human l-type phosphofructokinase. Biochem Soc Trans 1 April 1981; 9 (2): 358P. doi: https://doi.org/10.1042/bst009358p Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1981 Biochemical Society1981 Article PDF first page preview Close Modal You do not currently have access to this content.
ChemInform Abstract: Asymmetric Synthesis of (2R,3S) and (2S,3R) Precursors of β‐ Methyl‐histidine, ‐phenylalanine and ‐tyrosine. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A Resilient Leader Election Algorithm Using Aggregate Computing Blocks (2020)

Leader election, a fundamental coordination problem in distributed systems, has been addressed in many different ways. Among these works, resilient leader election algorithms are of particular interest due to the ongoing emergence of open, complex distributed systems such as smart cities and the Internet of Things. However, previous algorithms with O(diameter) stabilization time complexity either assume some prior knowledge of the network or that very large messages can be sent. In this paper, we present a resilient leader election algorithm with O(diameter) stabilization time, small messages, and no prior knowledge of the network. This algorithm is based on aggregate computing, which provides a layered approach to algorithm development based on composition of resilient algorithmic "building blocks." With our algorithm, a key design parameter K defines important performance attributes: a larger K will delay the recovery from loss of current leader, while a small K may lead to multiple leaders, and the algorithm will stabilize with O(diameter) time complexity when K ≥ 2.
Study of Mo, Au, and Ni Implanted Molybdenum Laser Mirrors By Spectroscopic Ellipsometry (1988)

The implantation of 150 kev molybdenum ions into polished molybdenum laser mirrors is found to increase the complex dielectric constant in the visible spectrum. Analysis using the Bruggeman effective medium approximation demonstrates that the increase is due to surface smoothing and that the surface is made nearly atomically smooth by a fluence of 5 × 1015/cm2. Implantation of Au at 1Mev caused considerable microscopic roughening, as well as a change in the bulk optical properties. 3 MeV Ni ion implantation caused only a slight surface roughening. A thin dielectric film (probably a hydrocarbon) is found to condense in a laboratory atmosphere, reducing the reflectivity, and is removable by rinsing with methanol and distilled water.
High electron mobility In2O3(001) and (111) thin films with nondegenerate electron concentration (2010)

Temperature dependent Hall measurements were applied to demonstrate, semiconducting n-type high-quality In2O3(001) and (111) thin films with nondegenerate unintentionally doped (UID) electron concentrations on the order of 1017 cm−3 at room temperature, which is below those of bulk single crystals. The freeze-out of the electron concentration in all samples suggests a shallow UID donor with ionization energy in the 17 meV range. Postgrowth annealing in oxygen allowed to further decrease the UID electron concentration with simultaneous mobility increase, suggesting oxygen vacancies to be the shallow UID donors. Hall mobilities above 200 cm2/V s at room temperature and 1000 cm2/V s at low temperatures exceed those of bulk single crystals and demonstrate high material quality and purity.
Design and analysis of a combined micro-computed tomography and optical structured light system for breast conserving surgery specimen margin imaging (2022)

Breast conserving surgery re-excision rates are high due to insufficient intraoperative guidance available to the surgeon. Post-operative studies have demonstrated that micro-CT and optical structured light have potential to determine margin status, but typical systems for these modalities are not specifically designed for use in surgical guidance. This study reports on the design and analysis of such a multimodal imaging system and is the first of its kind built specifically for use during breast conserving surgery. The custom system is based on a commercial IVIS SpectrumCT micro-CT scanner (PerkinElmer, Hopkinton, MA) without standard optical and bioluminescence imaging hardware and instead houses multiline lasers (Streamline Lasers, Osela Inc., Lachine, QC, Canada) mounted to a translation stage (DDSM100, Thorlabs, Newton, NJ), and a fast readout CMOS camera (Blackfly S USB 3.0, FLIR, Wilsonville, OR) for reflectance-based optical active line scanning. The system requires minimal training to operate and performs imaging and visualization of scans rapidly. Image processing uses the Insight Toolkit (ITK 5.1.2, Kitware, Clifton Park, NY), CT reconstruction uses the Reconstruction Toolkit (RTK 2.2.0, RTK Consortium, Villeurbanne, France) with CUDA (NVIDIA, Santa Clara, CA) for speed enhancement, and data visualization leverages the Visualization Toolkit (VTK 8.2.0, Kitware, Clifton Park, NY). Resolution and image quality metrics are comparable to current pre-clinical research systems, while scans are performed faster and with streamlined software for interacting with image data in near real-time. This study represents the advancement of multimodal micro-CT and optical structured light imaging toward clinical translation for margin detection during breast conserving surgery.
Integrating image matching and classification for multimedia retrieval on the Web (2003)

With the recent explosive growth in the volume of images on the World Wide Web, it has become increasingly difficult to search for images of interest. The classification of images helps users to access a large image collection efficiently. Classification reduces search space by filtering unrelated images. We present a technique for image classification based on color, shape and composition using the primary objects. Our experimental results show that this approach can maintain 73% of recall just by searching 24% of the whole data set. The classification results are also used to improve the users' interaction. The retrieval candidates are categorized based on the primary objects and presented to the users. We also show how we apply such technique to assist users in navigation.