gebhart/patrepeval huggingface dataset:
Wearable Folded Planar Dipole Antenna: Design and assessment for on-body wireless communication devices (2022)

A folded planar dipole antenna was designed and customized to operate close to the human body. Backward radiation was reduced to protect the human body from unwanted electromagnetic (EM) emissions and increase the antenna’s operating range. The antenna design was based on the concept of a folded planar dipole, which presents favorable impedance bandwidth (BW) characteristics. For integrability and robustness during usage in real environments, the antenna was completely covered by resin, taking into account the tradeoff between the antenna’s radiation performance, protection, and isolation. Measurements demonstrated a 10-dB impedance BW of 470 MHz (18.76%) covering the 2.27–2.74-GHz band. The maximum gain at 2.45 GHz was 1.4 dB isotropic (dBi). The antenna has a nearly omnidirectional pattern, occupies 77 × 35 × 11.15 mm, and weighs 120 g, making it easy to integrate with clothes. The resin packaging increased the mechanical robustness and improved the design’s isolation from external interference and perturbations; however, it reduced the radiation efficiency to 48.35%. The presented antenna is an excellent candidate for many wireless applications, in particular, applications where withstanding exposure to external mechanical strains and EM perturbations is required.
Single-cell transcriptomes of developing and adult olfactory receptor neurons in Drosophila (2021)

Recognition of environmental cues is essential for the survival of all organisms. Transcriptional changes occur to enable the generation and function of the neural circuits underlying sensory perception. To gain insight into these changes, we generated single-cell transcriptomes of <i>Drosophila</i> olfactory- (ORNs), thermo-, and hygro-sensory neurons at an early developmental and adult stage using single-cell and single-nucleus RNA sequencing. We discovered that ORNs maintain expression of the same olfactory receptors across development. Using receptor expression and computational approaches, we matched transcriptomic clusters corresponding to anatomically and physiologically defined neuron types across multiple developmental stages. We found that cell-type-specific transcriptomes partly reflected axon trajectory choices in development and sensory modality in adults. We uncovered stage-specific genes that could regulate the wiring and sensory responses of distinct ORN types. Collectively, our data reveal transcriptomic features of sensory neuron biology and provide a resource for future studies of their development and physiology.
A Novel Method for the Detection of Sticking of Tablets (1999)

The purpose of this work was to develop an instrumented upper punch to measure the adhesion force which occurs when the punch detaches itself from the upper surface of the tablet after compression. A specially designed adhesion force sensor instrumented with semiconductor strain gauges was inserted into an upper punch with a 25-mm punch face diameter suitable for a Korsch EK II eccentric press. Sorbitol, microencapsulated acetylsalicylic acid (ASA), and a formulation of a new active ingredient resulted in characteristic pull-off signals, providing a quantitative measure of the adhesion force. With "sticking-free" substances such as microcrystalline cellulose, tension signals could not be obtained; only Starch 1500 showed small adhesion force signals that indicated a sticking tendency. The compression force had a specific influence on the extent of the adhesion force; increasing the compression force caused an increase (sorbitol) or a decrease (ASA) of the adhesion force signals due to the plastic and elastic behavior of the substances. Depending on running time, ASA showed an increase in the adhesion force, reaching a plateau after 150 tablets. The addition of lubricants such as magnesium stearate resulted in smaller adhesion forces. The instrumented upper punch is a new helpful tool for the quantification of sticking and a valuable instrument in the development of formulations.
Effect of Passive Reflectors for Enhancing Coverage of 28 GHz mmWave Systems in an Outdoor Setting (2019)

The availability of large unused spectrum at millimeter wave (mmWave) frequency bands has steered the future 5G research towards these bands. However, mmWave signals are attenuated severely in the non-line-of-sight (NLOS) scenarios, thereby leaving the strong link quality by a large margin to line-of-sight (LOS) links. In this paper, a passive metallic reflector is used to enhance the coverage for mmWave signals in an outdoor, NLOS propagation scenarios. The received power from different azimuth and elevation angles are measured at 28 GHz in a parking lot setting. Our results show that using a 33 inch by 33 inch metallic reflector, the received power can be enhanced by 19 dB compared to no reflector case.
Antidepressant-like effects of nicotinic acetylcholine receptor antagonists, but not agonists, in the mouse forced swim and mouse tail suspension tests (2008)

Current literature suggests involvement of nicotinic acetylcholine receptors (nAChRs) in major depression. However, it is controversial whether the antidepressant-like effect of nAChR modulation is induced by activation, desensitization or inhibition of central nAChRs. In addition, the specific nAChR subtype/s involved remains unknown. In this study, we systematically compared the effects of non-selective and selective nicotinic agonists and antagonists in two different tests for antidepressant effects in mice: the tail suspension test and the forced swim test. Compounds: nicotine, RJR-2403 (alpha4beta2-selective agonist), PNU-282987 (alpha7-selective agonist), mecamylamine (non-selective antagonist), dihydro-beta-erythroidine (DHbetaE; alpha4beta2-selective antagonist), methyllycaconitine (MLA; alpha7-selective antagonist) and hexamethonium (non-brain-penetrant non-selective antagonist). All compounds were tested in a locomotor activity paradigm to rule out non-specific stimulant effects. The data show that blockade of nAChRs with mecamylamine, or selective antagonism of alpha4beta2 or alpha7 nAChRs with DHbetaE or MLA, respectively, has antidepressant-like effects. These effects were not confounded by motor stimulation. Hexamethonium did not show antidepressant-like activity, supporting the involvement of central nAChRs. At the dose levels tested, none of the nAChR agonists displayed antidepressant-like profiles. In conclusion, antagonism of central alpha4beta2 and/or alpha7 nAChRs induced antidepressant-like effects in mice. A strategy involving antagonism of central nAChRs could potentially lead to the development of novel antidepressant therapeutics.
Modèle prédictif du BNP en hémodialyse : impact paradoxal du statut cardiaque et de l’obésité (2017)

Le BNP est un marqueur biologique corrélé à l’hypertrophie ventriculaire gauche et la mortalité cardiovasculaire en hémodialyse. Son utilité comme marqueur prédictif de la volémie reste controversé. Nous avons développé un modèle mathématique permettant de prédire les variations du BNP en fonction des paramètres classiques (clinique et biologique) utilisés pour déterminer la volémie des patients en hémodialyse. Étude monocentrique, rétrospective sur 140 patients en hémodialyse (âge moyen = 67 ± 15 ans). Onze paramètres cliniques et biologiques étaient disponibles pour construire le modèle : l’âge, l’ethnie, diabète, la cardiopathie sous-jacent (CV), le BMI, le BNP, l’hémoglobine (Hb), la prise de poids interdialytique (PPID), la pression artérielle (PA) et le poids sec (NHYW) déterminé par body composition monitor (BCM). Nous disposons pour chaque paramètre de 6 mesures mensuelles consécutives. Sur les onze variables, seuls six contribuent au modèle final prédictif du BNP : l’âge, la PA, la PPID, le NHYW, l’Hb et la CV. Le modèle montre que le BNP est une fonction linéaire de la PPID et de l’Hb, également une fonction linaire du NHYW avec un coefficient dépendant de la CV et une fonction non linéaire (logistique) de l’âge et la PA. Un patient de 69 ans, normotendu, avec une PPID de 1,9 kg a un BNP prédit de 265 ng/mL, qui augmente à 425 ng/mL en cas de CV associée. L’augmentation du BNP liée à la CV semble inversement proportionnel au poids, et l’effet disparaît pour un NHYW > 100 kg. L’ajustement du modèle sur la cohorte d’apprentissage est assez bon (r = 0,56) Le modèle a été validé dans un 2e temps sur une cohorte de 62 patients incidents (r = 0,51) Le modèle mathématique montre que l’interprétation du BNP dépend d’une combinaison complexe de plusieurs facteurs n’ayant pas la même contribution. La comparaison du BNP « prédit » et du BNP « vrai » du patient permettra d’affiner l’état d’hydratation du patient, notamment dans les situations cardiaques complexes. L’utilisation et intérêt clinique du modèle restent à préciser des études interventionnelles prospectives. La modélisation du BNP des patients dialysés permet de prédire le taux de BNP pour chaque patient en fonction de ses caractéristiques cliniques et pour une hydratation extra-cellulaire adéquate.
Novel Orthogonal CPW Feeds for Dieletric Resonator Antennas (2004)

International audience
Seven-nanosecond time-resolved resonance Raman spectrometry of cytochrome c (1978)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSeven-nanosecond time-resolved resonance Raman spectrometry of cytochrome cWilliam H. Woodruff and Stuart. FarquharsonCite this: Anal. Chem. 1978, 50, 9, 1389–1391Publication Date (Print):August 1, 1978Publication History Published online1 May 2002Published inissue 1 August 1978https://pubs.acs.org/doi/10.1021/ac50031a050https://doi.org/10.1021/ac50031a050research-articleACS PublicationsRequest reuse permissionsArticle Views77Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Adaptive motion-copying system based on real-world haptics (2010)

This paper proposes adaptive motion-copying system, which is capable of storage and reproduction of human motion. In the conventional method, force and position are not reproduced accurately, when the environment in the reproduction phase is different from the environment in the storage phase. To solve this problem, the proposed method reproduces the human motion according to search results provided by environmental search algorithm. Therefore, the force and position corresponding to the stored motion is able to be reproduced even if the environment is changed. By the experiment, validity of the proposed method is verified.
Antibodies Against Autologous Tumor Cell Proteins in Patients With Small-Cell Lung Cancer: Association With Improved Survival (1993)

These data suggest that an antitumor immune response may affect tumor growth, and that the anonymous proteins detected by antitumor antibodies in lung cancer patient sera may represent proteins involved in the development of lung cancer or in its clinical manifestations.
Comparison of the distribution of bromine-77-bromovinyl steroidal and triphenylethylene estrogens in the immature rat. (1990)

The specific uptake and distribution of steroidal and non-steroidal [77Br]bromovinylestrogens were studied in immature female rats to assess the potential of these radioligands for imaging or therapy of estrogen receptor (ER) positive cancers. E-17 alpha [77Br]bromovinylestradiol, its 3 methyl ether and 11 beta-methoxy derivative, as well as the triphenylethylene estrogen, 1,1-bis[4-hydroxy-phenyl]-2-[77Br]bromo-2- phenylethylene all showed diethylstilbestrol inhibitable, specific uptake of radiobromine between 2 and 16 hr after i.p. administration. The highest concentrations in the estrogen target tissues and the highest target tissue-to-blood ratios were found with E-17 alpha-[Br]bromovinyl-11 beta-methoxyestradiol, but it also had rather high nonspecific uptake in all tissues. The triphenylethylene estrogen showed comparable specific uptake in estrogen target tissues to 17 alpha [77Br]bromovinylestradiol at 2 hr but better apparent retention, indicated by higher specific target tissue levels at the later time points. Thus, [77Br]bromovinyl-11 beta- methoxyestradiol and 1,1-bis[4-hydroxyphenyl]-2-[77Br]bromo-2-phenylethylene appear most favorable for these applications.
Optimal FDMA over wireless fading mobile ad-hoc networks (2008)

We formulate a frequency-division multiple access (FDMA) networking problem for wireless mobile ad-hoc networks (MANETS) to jointly optimize end-to-end user rates, routes, link capacities, transmitted power, frequency and power allocation across subcarriers and fading states. We show that the resulting non-convex optimization problem has zero duality gap. For some types of FDMA networks this result is exploited to reformulate the original problem into a (computationally tractable) convex optimization problem. We further exploit the lack of duality gap to show that conventional layering can be optimal in FDMA wireless MANETS. Specifically, if we select Lagrange multipliers appropriately, we can decompose the original problem in smaller sub-problems associated with the conventional networking layers. The solution of these per-layer optimization problems coincides with the solution of the originally formulated cross-layer optimization problem.
Chemical robot for enzymatic reactions and extraction processes of DNA in DNA sequence analysis. (1990)

A chemical robot capable of performing enzymatic reactions and extraction processes of DNA has been developed. The basic functions of this robot include handling of plastic tubes with caps, micropipetting, mixing, microcentrifuging and incubating. As a result, almost all of the pre-electrophoresis steps can be carried out. In addition, because these processes are automated, the working time of each process can be reduced. The reproducibility of the automated operation is equivalent to that of a skilled operator.
Data from Targeting of HPV-16<sup>+</sup> Epithelial Cancer Cells by TCR Gene Engineered T Cells Directed against E6 (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; The E6 and E7 oncoproteins of HPV-associated epithelial cancers are in principle ideal immunotherapeutic targets, but evidence that T cells specific for these antigens can recognize and kill HPV&lt;sup&gt;+&lt;/sup&gt; tumor cells is limited. We sought to determine whether TCR gene engineered T cells directed against an HPV oncoprotein can successfully target HPV&lt;sup&gt;+&lt;/sup&gt; tumor cells.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; T-cell responses against the HPV-16 oncoproteins were investigated in a patient with an ongoing 22-month disease-free interval after her second resection of distant metastatic anal cancer. T cells genetically engineered to express an oncoprotein-specific TCR from this patient's tumor-infiltrating T cells were tested for specific reactivity against HPV&lt;sup&gt;+&lt;/sup&gt; epithelial tumor cells.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; We identified, from an excised metastatic anal cancer tumor, T cells that recognized an HLA-A*02:01–restricted epitope of HPV-16 E6. The frequency of the dominant T-cell clonotype from these cells was approximately 400-fold greater in the patient's tumor than in her peripheral blood. T cells genetically engineered to express the TCR from this clonotype displayed high avidity for an HLA-A*02:01–restricted epitope of HPV-16, and they showed specific recognition and killing of HPV-16&lt;sup&gt;+&lt;/sup&gt; cervical, and head and neck cancer cell lines.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; These findings demonstrate that HPV-16&lt;sup&gt;+&lt;/sup&gt; tumors can be targeted by E6-specific TCR gene engineered T cells, and they provide the foundation for a novel cellular therapy directed against HPV-16&lt;sup&gt;+&lt;/sup&gt; malignancies, including cervical, oropharyngeal, anal, vulvar, vaginal, and penile cancers. &lt;i&gt;Clin Cancer Res; 21(19); 4431–9. ©2015 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Thermal Stress Limits of Plates Subjected to Extremely High Heat Flux (1996)

Abstract For heat fluxes in the range of 20 MW/m2 to 400 MW/m2, solid surfaces usually experience large thermal stresses and degradation of mechanical properties. The resulting mechanical failure of such surfaces is a primary limitation to the design of thermal systems at extremely high heat flux. This paper is an investigation of the general mechanical behavior of plates operated at extremal fluxes. Two prototypical configurations are considered. Several candidate materials are examined, accounting for the temperature dependence of thermal and mechanical properties. The elastic performance of plates at high flux is investigated and conditions for yielding are identified for various materials, mechanical restraints, and heat source distributions. Plastic behavior, which is characteristic of higher flux levels, is also examined. New material figures of merit are developed, taking account of the temperature dependence of thermal, elastic, and/or plastic properties.
partDSA: deletion/substitution/addition algorithm for partitioning the covariate space in prediction (2010)

Supplementary data are available at Bioinformatics online.
Backside laser testing of ICs for SET sensitivity evaluation (2001)

A new experimental approach combining backside laser testing and analog mapping is presented. A new technique for integrated circuits (ICs) backside preparation by laser ablation is evaluated. The methodology is applied to the study of single-event transient (SET) sensitivity on a linear IC.
Nonlinear pulsing schemes for the detection of ultrasound contrast agents (2008)

Ultrasound contrast agents are used in cardiology for the assessment of myocardial perfusion and in radiology for the detection and characterization of tumors. One widely used approach of imaging contrast agents is to use a low Mechanical Index (MI) nonlinear imaging technique to avoid bubble destruction and image both the macro- and micro-circulation in real-time. Various pulsing schemes are employed for the detection of nonlinear echoes from contrast microbubbles. The objective of this paper is to evaluate the various pulsing schemes for low MI imaging of contrast microbubbles and better understand their similarities and differences. The pulsing schemes considered are pulse inversion, power modulation, and their combination. Emphasis is placed on identifying whether nonlinearity due to propagation in tissue may be discriminated from nonlinearity due to scattering from bubbles. Bubble destruction (use of high MI) and tissue motion were not considered in this work. The evaluation of the different pulsing schemes was performed with numerical simulations from well established theoretical models and experimental data from microbubbles in tissue phantoms and human tissues.
Charge-based ZVS soft switching analysis of a single-stage dual active bridge AC-DC converter (2013)

A semi-analytical modulation scheme to operate a single-phase, single-stage dual active bridge (DAB) AC-DC converter under full-operating-range zero voltage switching (ZVS) is proposed. The converter topology consists of a DAB DC-DC converter, receiving a rectified AC line voltage via a synchronous rectifier. ZVS modulation strategies previously proposed in literature are either based on current-based (CB) or energy-based (EB) ZVS analyses. The combined phase-shift, duty-cycle, and switching frequency modulation proposed in this paper relies on a novel, current-dependent charge-based (CDCB) ZVS analysis, taking into account the commutation charge of the (parasitic) switch capacitances as well as the time dependency of the commutation currents. Thereby, commutation inductance is shown to be an essential element in achieving full-operating-range ZVS. Experimental results obtained from a 3.7 kW bidirectional electric vehicle battery charger which interfaces a 400 V DC-bus with the 230 Vac, 50 Hz utility grid are given to validate the analysis and practical feasibility of the proposed strategy.
Rapid Detection to Differentiate Hypervirulent Klebsiella pneumoniae (hvKp) From Classical K. pneumoniae by Identifying peg-344 With Loop-Mediated Isothermal Amplication (LAMP) (2020)

The LAMP assay is easy to perform and rapid. Therefore, it can be routinely applied to differentiate hvKp from cKp in the clinical laboratory.
A database-oriented wrapper for ubiquitous data acquisition/access environments (2008)

Ubiquitous data acquisition/access environments are dynamic because the number and kinds of devices used to access information are constantly changing. System designers must often identify and incorporate devices and implement ad-hoc application systems based on the environment to execute tasks. The constant change in the environment and the huge number of devices make it difficult and time-consuming for system designers to construct application systems using existing programming styles. We propose a system construction platform based on a relational database mechanism. Devices and the functions are regarded as tables, tuples, and SQL queries. This platform makes it easy to manage huge numbers of devices in a ubiquitous data acquisition/access environment and provides a method of ad-hoc system construction that is accessible to many devices and can accommodate their functions.
Polylithic Integration for RF/MM-Wave Chiplets using Stitch-Chips: Modeling, Fabrication, and Characterization (2020)

A polylithic integration technology is demonstrated for seamless stitching of RF and digital chiplets. In this technology, stitch-chips with compressible microinterconnects (CMIs) are used for low-loss and dense interconnection between chiplets. A testbed using fused-silica stitch-chips with integrated CMIs is demonstrated including modeling, fabrication, assembly, and characterization. A 500 µm-long stitch-chip signal link is measured to have less than 0.4 dB insertion loss up to 30 GHz. A simulated eye diagram for 1000 µm-long stitch-chip signal link has a clear opening at 50 Gbps data rate. Moreover, the S-parameters of the CMIs are extracted from this testbed and show less than 0.17 dB insertion loss up to 30 GHz. Benchmarking to silicon interposer based interconnection is also reported.
Kenaf Fiber-Reinforced Biomass-Plastics Used for Electronic Products (2006)

We have developed high-performance biomass-based plastics that consist of polylactic acid (PLA) and fiber of kenaf; which fixates CO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> efficiently. Adding this fiber to PLA greatly increases its heat resistance and modulus and also enhances its crystallization. Eliminating the short particles from the kenaf fiber improves its effect on impact strength. Furthermore, adding a flexibilizer mainly made with biomass to the composite improves its strength. These composites (PLA/kenaf fiber, PLA/kenaf fiber/flexibilizer) show good practical characteristics as a housing material of electronic products, compared to petroleum-based plastics such as glass fiber-reinforced ABS resin