gebhart/patrepeval huggingface dataset:
Protonenrelaxation in Mn2+‐Lösungen, Einfluß der Hyperfeinkopplung. I. Theorie (1966)

1 An extension of the usual Redfield relaxation-matrix theory is derived for the case P(τ) ≠ P(−τ). It is shown that the definition of a relaxation-matrix R and a shift-matrix V as introduced by Pfeifer is useful. Equations analogous to the Kronig-Kramers- relations are valid between the spectral densities 𝔧(ω) (contained in R) and 𝔦́ (ω) (contained in V). A general solution of the differential equations is discussed. 2 If the operator S of the electron spin may be regarded as a lattice operator, expressions for the proton relaxation times in solutions of paramagnetic ions are developed. The influence of the paramagnetic ions on the proton relaxation is described by the relaxation function rq(τ) of the electron spin which may be determined by esr-experiments or by theory. 3 rq(τ) is calculated for Mn2+-ions in weak fields using a spin-Hamiltonian which includes Zeeman-energy, hyperfine coupling \documentclass{article}\pagestyle{empty}\begin{document}$ \left({a \cdot \,\vec S \cdot \,\vec K\,} \right) $\end{document}, and zero field splitting. Moreover the calculation is extended to any field for a hypothetical ion (S = K = 1/2) the relaxation mechanism of which is assumed to be caused by a hypothetical stochastic field (Abragam model). 4 The results show that the influence of hyperfine coupling is generally not negligible. In weak fields the relaxation rates may be only 50% of the values derived from the usual high field equations. In medium fields an anomale frequency dependence may occur. 5 Similar effects are to be expected for all paramagnetic ions which show a well resolved hyperfine splitting in solution (e. g. V2+-ions).
Search for the rare decay Λ[subscript c][superscript +] → pμ[superscript +]μ[superscript −] (2018)

A search for the flavor-changing neutral-current decay Λ[subscript c][superscript +]→pμ[superscript +]μ[superscript -] is reported using a data set corresponding to an integrated luminosity of 3.0 fb[superscript -1] collected by the LHCb Collaboration. No significant signal is observed outside of the dimuon mass regions around the ϕ and ω resonances, and an upper limit is placed on the branching fraction of B(Λ[subscript c][superscript +]→pμ[superscript +]μ[superscript -])<7.7(9.6)×10[superscript -8] at 90%(95%) confidence level. A significant signal is observed in the ω dimuon mass region for the first time.
The Future of Engineered Living Sensors ─ I Hope It Is Not the Thing with Feathers (2022)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTThe Future of Engineered Living Sensors ─ I Hope It Is Not the Thing with FeathersMichael J. SailorMichael J. SailorMore by Michael J. Sailorhttps://orcid.org/0000-0002-4809-9826Cite this: ACS Sens. 2022, 7, 10, 2795–2796Publication Date (Web):October 28, 2022Publication History Received6 October 2022Published online28 October 2022Published inissue 28 October 2022https://pubs.acs.org/doi/10.1021/acssensors.2c02178https://doi.org/10.1021/acssensors.2c02178editorialACS PublicationsCopyright © 2022 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views1319Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (1 MB) Get e-AlertscloseSUBJECTS:Bacteria,Bioengineering and biotechnology,Coal,Sensors,Synthetic biology Get e-Alerts
Structural Variations of N‐Acetylneuraminic Acid, 10. Synthesis of 2,7‐, 2,8‐, and 2,9‐Dideoxy‐ and 2,4,7‐Trideoxy‐2,3‐didehydro‐N‐acetylneuraminic Acids and Their Behavior Towards Sialidase from Vibrio cholerae (1989)

Abstract The peracetylated methyl ester derivatives of 7‐deoxy‐Neu5Ac ( 2a ), 8‐deoxy‐Neu5Ac ( 3a , 9‐deoxy‐Neu5Ac ( 4a ), and 4,7‐dideoxy‐Neu5Ac ( 5a ) were transformed by trimethylsilyl trifluoromethanesulfonate into the corresponding 2‐deoxy‐2,3‐didehydro derivatives 2b–5b . As additional products, the 4,5‐oxazolino derivatives 6b–8b were formed. Hydrolysis of 2b–5b yielded the free acids 7‐deoxy‐Neu5Ac2en ( 2c ), 8‐deoxy‐Neu5Ac2en ( 3c ), 9‐deoxy‐Neu5Ac2en ( 4c ), and 4,7‐dideoxy‐Neu5Ac2en ( 5c ). They showed significantly different inhibitory influences on the hydrolysis of 4‐methylumbelliferyl‐α‐Neu5Ac by sialidase from Vibrio cholerae . The comparison of their evaluated α‐side profiles with that of Neu5Ac2en ( 1c ) enables a suitable explanation of their different inhibitory potencies.
ChemInform Abstract: Synthesis and Dopamine Receptor Binding of 3‐Phenylazepino(5,4,3‐c,d) indole Derivatives. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Guest Editorial (2020)

introduction Free Access Share on Guest Editorial: ACM JETC Special Issue on New Trends in Nanolectronic Device, Circuit, and Architecture Design: Part 2 Editors: Wei Zhang The Hong Kong University of Science and Technology, Clear Water Bay, NT, Hong Kong SAR The Hong Kong University of Science and Technology, Clear Water Bay, NT, Hong Kong SARView Profile , Helen Li Duke University Durham, NC 27708 USA Duke University Durham, NC 27708 USAView Profile , Wujie Wen Lehigh University Bethlehem, PA 18015 USA Lehigh University Bethlehem, PA 18015 USAView Profile , Swarup Bhunia University of Florida Gainesville, FL 32611 University of Florida Gainesville, FL 32611View Profile Authors Info & Claims ACM Journal on Emerging Technologies in Computing SystemsVolume 16Issue 4October 2020 Article No.: 35pp 1–3https://doi.org/10.1145/3412343Published:23 September 2020Publication History 0citation232DownloadsMetricsTotal Citations0Total Downloads232Last 12 Months40Last 6 weeks2 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteView all FormatsPDF
<title>Effects of particle shape on particle identification and scatter predictions</title> (2001)

Laser particle scanners are traditionally calibrated with polystyrene latex spheres, and these spheres are used to create a sizing scale in light scatter equivalents. Particle scatter signals can vary strongly with particle materials, thus concealing the true particle size. As previously reported, particle material identification in a laser scanner will allow true sizing of spherical particles through the application of accurate scatter models. This paper reports extending that work to non-spherical particles through the use of modeling scatter from ellipsoidal particles.
IDDF2018-ABS-0058 Early normalisation of alanine aminotransferase (alt) after nucleos(t)ide analogue treatment reduces the risk of hepatocellular carcinoma (hcc) in patients with chronic hepatitis b – a territory-wide study of 21,182 subjects (2018)

<h3>Background</h3> We aimed to evaluate the impact of alanine aminotransferase (ALT) normalisation (ALTN) achieved at different time after the start of antiviral treatment on the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B (CHB). <h3>Methods</h3> We identified a territory-wide cohort of CHB patients who received entecavir and/or tenofovir disoproxil fumarate (TDF) for ≥1 year between 2005 and 2016 in Hong Kong. Serial on-treatment ALT levels were analysed. ALTN referred to ALT level lower than the upper limit of normal (ULN) (30 U/L in males and 19 U/L in females). Early ALTN was defined as ALTN within 12 months. The primary outcome was HCC based on ICD-9-CM diagnosis codes. Patients with cancers previously or during the first year of treatment were excluded. <h3>Results</h3> 21,182 CHB patients (10 437 with and 10 745 without ALTN at 12 months after antiviral treatment) were identified and followed for a median (interquartile range) of 4.1 (2.4–6.0) years. Patients with or without ALTN at 12 months differed in gender distribution (76.9% <i>vs</i>. 58.4% male), baseline ALT (58 <i>vs.</i> 61 U/L), baseline serum HBV DNA (4.9 <i>vs.</i> 5.1 log<sub>10</sub>IU/mL), proportion of positive hepatitis B e antigen (31.5% <i>vs.</i> 37.1%), and presence of cirrhosis (8.8% <i>vs.</i> 10.5%) and diabetes mellitus (8.1% <i>vs.</i> 9.1%); 509 (2.4%) patients developed HCC. ALTN at 3, 6, 9 and 12 months were associated with a reduced risk of HCC (Figure 1), with adjusted hazard ratios (aHR) (95% confidence interval [CI]) of 0.55 (0.42,0.71), 0.52 (0.41,0.64), 0.47 (0.38,0.58) and 0.46 (0.37,0.56), respectively (all p&lt;0.001). In contrast, ALT 1 to 2 times the ULN and ALT greater than 2 times the ULN at 12 months were associated with a higher risk of HCC as compared to ALTN at 12 months, with aHR (95% CI) of 2.07 (1.67,2.56) and 3.21 (2.32,4.44), respectively, after adjustment for baseline ALT and important covariates. <h3>Conclusions</h3> Early on-treatment ALTN reduces the risk of HCC in CHB patients having entecavir/TDF treatment. On-treatment ALT above 1 and 2 times the ULN at 12 months were associated with higher risk of HCC.
Association between urine cotinine levels, continuous performance test variables, and attention deficit hyperactivity disorder and learning disability symptoms in school-aged children (2012)

Our data indicate that environmental exposure to tobacco smoke is associated with ADHD and learning disabilities in children, and that impairments in attention and inhibitory control probably mediate the effect.
A novel ergonomic optical coherence tomography probe optimized for supine handheld angiography of young children and infants (Conference Presentation) (2019)

Optical coherence tomography angiography (OCTA) is an extension of OCTA that allows for non-invasive imaging of the retinal microvasculature. OCTA imaging of adult retinal diseases is area of active research in ophthalmology as OCTA can provide insight into the pathogenesis of many retinal diseases. Like these adult diseases, pediatric diseases such as retinopathy of prematurity (ROP) have a primarily vascular pathogenesis. However, table top OCTA systems require compliant, seated subjects and cannot be used on infants and young children. In this manuscript we describe the development of a non-contact handheld OCTA (HH-OCTA) probe for imaging of young children and infants in the operating room. The probe utilizes a novel, diverging light on the scanner optical design that provides improved performance over a traditional OCT scanner design. While most handheld OCT probes are designed to be held by the side of the case or by a handle, our operators tend to prefer to grip probes by the tip of the probe for supine imagine. The ergonomics of the HH-OCTA probe were designed to match this grip. The HH-OCTA probe used a 200 kHz OCT engine, has a motorized stage that provides +10 to -10 D refractive error correction, and weighs 700g. Initial OCTA imaging was performed in 9 children or infants during exam under anesthesia. The HH-OCTA images provide visualization of the retinal microvasculature in both normal and pathological eyes.
Supplementary Figure 7 from Fibroblast Growth Factor Receptor 4 Regulates Tumor Invasion by Coupling Fibroblast Growth Factor Signaling to Extracellular Matrix Degradation (2023)

Supplementary Figure 7 from Fibroblast Growth Factor Receptor 4 Regulates Tumor Invasion by Coupling Fibroblast Growth Factor Signaling to Extracellular Matrix Degradation
Impact of pre-existing specific influenza antibodies as a determinant of disease severity on influenza virus infected patients: a multicenter observational cohort study (2020)

Abstract It is unclear to what extent pre-existing antibody-mediated immunity shapes influenza virus infection in humans. Similarly, the influence of previous history of influenza vaccination on disease severity and clinical outcome is not well understood. In here, we aimed to determine the balance of pre-existing antibodies against the hemagglutinin (HA) and neuraminidase (NA) protein of influenza virus that correlates with protection in humans. We measured hemagglutination inhibition (HI) titers and anti-HA (stalk and full-length) and anti-NA antibodies at the onset of the influenza infection on a cohort of H1N1/Cal09 influenza virus-infected patients (solid organ transplant recipients, SOTRs). Results demonstrated that the antecedent of TIV vaccination was the only controllable factor associated with lower risk of severity of disease in influenza virus-infected SOTRs. The presence of lower respiratory symptoms (LRS) significantly determined disease outcome at hospital admission (severe vs. mild, 9, 75% vs. 19, 32·1%, OR 95% 6·3, p=0·01). Moreover, a predicted probability curve for both anti-HA full-length and stalk (OR 0·13, p=0·02 and OR 0·06, p=0·03, respectively) demonstrated that the probability of developing LRS decreased with increasing assay log-values. However, multivariate logit model adjusted for HI, anti-HA (full-length and stalk) and anti-NA titers demonstrated that only anti-HA stalk antibodies were independently associated with influenza severity. Our study demonstrated that when HI antibodies fail to confer protection from symptomatic influenza infection, pre-existing HA stalk antibodies protected against severe disease in SOTRs.
Simple method of measuring laser peak intensity inside femtosecond laser filament in air (2011)

Measurement of laser intensity inside a femtosecond laser filament is a challenging task. In this work, we suggest a simple way to characterize laser peak intensity inside the filament in air. It is based on the signal ratio measurement of two nitrogen fluorescence lines, namely, 391 nm and 337 nm. Because of distinct excitation mechanisms, the signals of the two fluorescence lines increase with the laser intensity at different orders of nonlinearity. An empirical formula has been deduced according to which laser peak intensity could be simply determined by the fluorescence ratio.
Real-Time Fluorescence Monitoring of the Polymerase Chain Reaction in a Novel Continuous Flow Reactor for Accurate DNA Quantification (2006)

Real-time Polymerase Chain Reaction (PCR) is the preferred method for quantification of gene expression levels due to its extreme sensitivity. Fluorescence based real-time PCR is commonly used for the quantification of the initial amount of a specific sequence of DNA. Real-time quantification may be achieved using fluorescent dyes, by optically monitoring the product formation as the PCR cycles progress. Stationary well based real-time quantification is quite common, however continuous flow real-time PCR which is the aim of this work is still in its infancy. A compact, high throughput continuous flow thermal cycler has been developed which allows for real-time fluorescent measurements to be obtained. The principle of operation of this device is that the three thermal zones required for a polymerase chain reactor are maintained on both sides of an aluminium block and bio-compatible FEP Teflon capillary tubing is then wrapped around these constant temperature blocks. The capillary tubing is wrapped around the device fifteen times which provides thirty PCR thermal cycles. The device has been designed and optimised to accurately monitor the product expression level using the double stranded DNA binding dye SYBR green I. Initially the PCR mixture is segmented into small nanoreactors, separated by an immiscible carrier fluid to eliminate cross contamination and reduce the likelihood of sample degradation due to contact with the capillary wall. These PCR nanoreactors are then cycled through the tubing and the DNA amplified. Fluorescent optical monitoring of these nanoreactors takes place where a water glycerine mixture, which is refractive index matched to the tubing, allows for improved fluorescent measurements of the nano-volume reactors to be obtained. Plasmid DNA, 240 base pairs long, has been successfully amplified using this device and the temperatures for the denaturation, annealing and extension phases have been accurately measured. Real-time fluorecence images of the flowing nano-volumes were recorded every second cycle using a CCD camera and from these images amplification curves have been successfully generated. Samples with various initial concentrations of DNA have been thermally cycled on the continuous flow reactor. The measured increase in fluorescence intensity from the flowing nano-volume reactors as they progressed through the thermal cycler demonstrated the effect of initial DNA template concentration.
Progettazione di un braccio strumentato per la macchina di misura degli pneumatici (2014)

Questa tesi illustra il percorso che ha portato alla progettazione di un braccio meccanico strumentato, con il quale equipaggiare la macchina di misura degli pneumatici (MotoTireMeter).Lo scopo di questo progetto e di migliorare il sistema attuale sotto due punti di vista: la quantita  di informazioni misurabili nell'interazione tra lo pneumatico ed il disco rotante, e l'accuratezza dei dati raccolti
An evaluation of concurrent priority queue algorithms (2002)

This paper describes the design and experimental evaluation of two novel concurrent priority queue algorithms, a parallel Fibonacci heap and a concurrent priority pool, and compares them with the concurrent binary heap. The parallel Fibonacci heap is based on the sequential Fibonacci heap, which is theoretically the most efficient data structure for sequential priority queues. The concurrent priority pool is based on the concurrent B-tree and the concurrent pool. Both new algorithms scale better and have large throughput than the concurrent binary heap, as shown by the performance results. These performance advantages are achieved by relaxing the semantics of the extract-min operation, allowing it to return items that are close to the minimum but not necessarily minimal. Two applications of concurrent priority queues, the vertex cover problem and the single source shortest path problem, are tested.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Erratum: Energy Levels of Ho3 + in LaCl3 (1968)

First Page
Resilience design in all-optical ultralong-haul networks (2006)

Feature Issue on High Availability in Optical NetworksAfter many years of research and industry efforts, ultralong-haul (ULH) technologies for DWDM transport are maturing, and carriers are deploying them for high capacity and capital savings. Unlike opaque optical networks, it is still uncertain how best to restore an all-optical ULH network after failure. This paper focuses on this issue and proposes a standby restoration scheme and its variants with different restoration speed and associated restoration cost. Our observations suggest that the proposed hot standby scheme would yield both faster restoration and cost efficiencies compared with other schemes.
A new model of time evolution of gate leakage current after soft breakdown in ultra-thin gate oxides (2003)

The post-SBD degradation of ultra-thin gate oxides is investigated by means of experiments, theoretical modeling, and computer simulations. The gate leakage current after SBD increases gradually, and is finally limited by the parasitic resistance. A newly developed model shows that the gate leakage increase of post-SBD MOSFETs even under operating conditions causes a significant impact on LSIs in terms of the power consumption.
Regulation by reactive oxygen species of pro-inflammatory genes in chondrocytes (2002)

peer reviewed
EUV reticle defectivity protection options (2019)

EUV pellicles have been enabled to provide customers with defect protection for EUV reticles. However, due to the absorption that is much higher than for DUV pellicles, using the pellicle has certain disadvantages. Most significant is the reduction in throughput caused by the absorption of EUV photons in the pellicle. This leads to a customer decision to use a pellicle and accept the reduced throughput, or to not use a pellicle and have additional inspection steps to check the cleanliness of the EUV reticle. These tradeoffs vary by customer and use case. This study addresses the balance of factors for using or not using a pellicle through a cost comparison.
Sideband intensities in two-dimensional NMR spectra of rotating solids (1987)

In the presence of magic angle sample spinning (MASS), two-dimensional solid-state NMR spectra of magnetically dilute I=1/2 nuclei split into rotational sidebands spaced at the spinning frequency in both dimensions. The intensities of these sidebands contain information on the sizes and relative orientations of the interactions present in the two experimental time domains. Here we extend an earlier analysis of sideband intensities in one-dimensional MASS spectra to two-dimensional MASS spectra. The resulting equations are applicable to heteronuclear and homonuclear correlation spectra, dipolar/chemical shift spectra, and slow chemical exchange spectra. We use the equations to deduce the orientation of the 15N chemical shift tensor in the amide group of L-asparagine⋅H2O from the sideband intensities in the 15N–1H dipolar/chemical shift spectrum. This application to an AX2 system enlarges on previous work with AX systems and may be generalized to AXn systems.
Molecular characterization and refined genomic localization of three human potassium ion channel genes (1995)

Potassium ion (K+) channels are essential for a variety of cellular functions in both excitable and non-excitable cells and are likely to be involved in the pathogenesis of some cardiovascular and neurological disorders. To be useful in candidate gene analysis of inherited diseases it is important to identify new K+ channel genes and localize these sequences on the human physical and genetic maps. Using fluorescence in situ hybridization (FISH), we mapped two new K+ channel gene containing cosmids, c2-3a and c9-2a, to chromosomes 1 and 19, respectively. Partial DNA sequencing (c2-3a) and restriction enzyme site analysis (c9-2a) established the uniqueness of each clone. We refined the localization of c2-3a, c9-2a and a previously described K+ channel gene KCNA5, (c7-2), by performing contour length measurements of hybridized metaphase chromosomes and determining the average FLpter% value (fractional length relative to the fixed reference point pter x 100%). When compared to ideograms of banded metaphase chromosomes, these FLpter% values correspond to 12p13.31-->p13.33, 1p13.1-->p21.1 and 19q13.32-->q13.33, respectively. Using FISH, each of these clones has been finely mapped to a different human chromosome indicating a significant dispersion of K+ channel sequences in the human genome.