gebhart/patrepeval huggingface dataset:
Optical properties of bimodally distributed InAs quantum dots grown on digital AlAs0.56Sb0.44 matrix for use in intermediate band solar cells (2017)

High-quality InAs quantum dots (QDs) with nominal thicknesses of 5.0–8.0 monolayers were grown on a digital AlAs0.56Sb0.44 matrix lattice-matched to the InP(001) substrate. All QDs showed bimodal size distribution, and their optical properties were investigated by photoluminescence (PL) and time-resolved PL measurements. Power dependent PL exhibited a linear relationship between the peak energy and the cube root of the excitation power for both the small QD family (SQDF) and the large QD family (LQDF), which is attributed to the type-II transition. The PL intensity, peak energy, and carrier lifetime of SQDF and LQDF showed very sensitive at high temperature. Above 125 K, the PL intensity ratio increased continuously between LQDF and SQDF, the peak energy shifted anomalously in SQDF, and the longer carrier radiative lifetime (≥3.0 ns at 77 K) reduced rapidly in SQDF and slowly in LQDF. These results are ascribed to thermally activated carrier escape from SQDF into the wetting layer, which then relaxed into LQDF with low-localized energy states.
PhotoScope (2009)

PhotoScope visualizes the spatiotemporal coverage of photos in a photo collection. It extends the standard photo browsing paradigm in two main ways: visualizing spatial coverage of photos, and indexing photos by a combination of spatial coverage, time, and content specifications. This approach enables users to browse and search space- and time-indexed photos more effectively. We designed PhotoScope specifically to address challenges in the construction management industry, where large photo collections are amassed to document project progress. These ideas may also apply to any photo collection that is spatially constrained and must be searched using spatial, temporal, and content criteria. We describe the design choices made when developing PhotoScope and the results of user evaluation.
Profitable services in an uncertain world (2005)

In a service-oriented, utility-computing, Grid-like world, service providers will execute jobs on behalf of their clients on systems rented from resource providers. This poses many challenges to the service provider, such as choosing which jobs to admit, when to run them, whether to execute them on one system or many, and how many resources to rent. To complicate matters, the service provider may experience resource uncertainty an inability to get the resources it needs or expects. The result will be sub-optimal choices of which jobs to accept and when to run them, and the service provider may have to pay penalties to its clients. Using an economics-based approach, we have developed scheduling policies that systematically address these problems. We show that the new policies deliver significantly more profit (or added value) than ones oblivious to such concerns.
Strain and process development for the production of human cytokines inHansenula polymorpha (2002)

The early status of strain development for the production of interleukin (IL)-6, IL-8, IL-10, and interferon (IFN) γ is described. The general approach to generating such strains was to amplify gene sequences encoding the mature forms of the various cytokines by PCR from commercially available cDNA sources. The design of the amplificates allowed an in-frame fusion to an MFα1 leader segment contained in two basic expression vectors, pFPMT121-MFα1 and pTPSMT-MFα1. The two vectors differ in that one harbors the methanol-inducible FMD promoter and the other the constitutive TPS1 promoter as control elements for heterologous gene expression. The most advanced process development example is that of IFNα-2a. Here, the MOX promoter derived from another key gene of methanol metabolism is used for expression control. The successful development of a production process for Hansenula polymorpha-derived IFNα-2a is summarized. This was achieved by combining genetic engineering of suitable production strains with improved processing capabilities for the secreted cytokine, and by purification procedures from cultures grown in yeast extract–peptone–glycerol-based media.
Combined Use of Chymosin and Protease from Cryphonectria parasitica for Control of Meltability and Firmness of Cheddar Cheese (2004)

The combined use of chymosin and Cryphonectria parasitica protease was evaluated for manufacturing Cheddar cheese at different chymosin-to-C. parasitica protease ratios of 1:0, 0:1, 67:33, and 33:67. The degree of proteolysis over time was affected by the coagulant type. Proteolysis was thought to be the main cause of changes in functional properties of Cheddar cheeses. The meltability and hardness of cheese made with 100% C. parasitica enzyme was the highest, but it was high in bitterness. The chymosin-to-C. parasitica ratio between 0:1 to 67:33 was found suitable to independently control Cheddar cheese meltability and hardness without a significant level of bitterness.
Temperature-Programmed Sputtered Micromachined Gas Chromatography Columns: An Approach to Fast Separations in Oilfield Applications (2012)

In a previous study, a new stationary phase deposition technique for micromachined gas chromatography columns was presented. The rerouting of the sputtering technique to this purpose enabled collective and reproducible fabrication of microcolumns in a silicon wafer. Silica-sputtered micromachined columns showed promising separations of light alkanes in isothermal conditions. In order to go beyond the limitations of isothermal separations, the columns were equipped with sputtered platinum filaments to enable high-speed and low-power temperature programming. The separation performances of temperature-programmed silica- or graphite-sputtered microcolumns were investigated: a separation of light alkanes (C1-C5) was completed in 9 s, and heavier alkanes (until C9), cyclic, isomeric, and unsaturated hydrocarbons were also successfully separated. Versatility of these microcolumns was demonstrated with a high-temperature C1-C2 separation and a C1-C5 separation with nitrogen as carrier gas instead of helium. By matching the requirements of a gas chromatography-based monitoring sensor, in terms of low-cost and industry-ready fabrication process, fast temperature programming and analysis, low power consumption, and good versatility (ambient temperature, carrier gas), these columns should be used in various applications related to oilfield gas analyses.
Aberrant plasma MMP and TIMP dynamics in Schistosoma - Immune reconstitution inflammatory syndrome (IRIS) (2018)

In this study, we propose a working definition for the diagnosis of Schisto-IRIS in resource limited settings. We report persistent plasma levels of MMP-10, along with a more pronounced decrease in TIMP-1 and ANA-levels, and low levels of TIMP-2 during 3 months of ART. Corresponding to the clinical symptoms, these data suggest that Schisto-IRIS is marked by unbalanced MMP/TIMP dynamics which favor inflammation.
“Scaffold-Hopping” by Topological Pharmacophore Search: A Contribution to Virtual Screening (1999)

A chemically advanced template search (CATS) based on topological pharmacophore models has been developed as a technique for virtual screening. This technique has successfully identified novel potent Ca2+ antagonists (such as 2) that have a similar activity to 1 (a known T-channel blocking agent) in a library of several hundred thousand compounds on the basis of a correlation vector representation.
Design and Evaluation of a Variable-Flux Flux-Intensifying Interior Permanent-Magnet Machine (2013)

This paper presents a design approach for interior permanent-magnet (IPM) machines with variable-flux characteristics using low-coercive-force magnets for improved efficiency and extended operating speed range. A flux-intensifying IPM type with is used in the design due to positive Id operation and reduced loaded Iq effects. Design considerations of machine structures and variable-flux machine attributes are discussed. In addition, leakage flux in a rotor is particularly designed to also obtain another flux-varying capability. Evaluation of the designed machine is provided by finite-element analysis simulations and experiments on a proof-of-principle machine. The designed machine shows benefits in increasing efficiency and speed range in a low-torque region when variable magnetization control of the low-coercive-force magnets or the design of the leakage flux proposed in this paper is implemented.
Broadband Rational Macromodeling Based on the Adaptive Frequency Sampling Algorithm and the Partial Element Equivalent Circuit Method (2008)

The increasing operating frequencies in modern designs call for broadband macromodeling techniques. The problem of computing high-accuracy simulation models for high-speed interconnects is of great importance in the modeling arena. Nowadays, many full-wave numerical techniques are available that provide high accuracy, often at a significant cost in terms of memory storage and computing time. Furthermore, designers are usually only interested in a few electrical quantities such as port voltages and currents. So, model order reduction techniques are commonly used to achieve accurate results in a reasonable time. This paper presents a new technique, based on the partial element equivalent circuit method, which allows to generate reduced-order models by adaptively selecting the complexity (order) of the macromodel and suitable frequency samples. Thus, the proposed algorithm allows to limit the computing time while preserving the accuracy. Validation examples are given.
Silicon nanomembrane based photonic crystal waveguide true-time-delay lines on a glass substrate (2013)

We demonstrate photonic crystal waveguide true-time-delay lines fabricated on a large area (&gt;2cm &times; 2cm) silicon nanomembrane transferred onto a glass substrate. The photonic crystal waveguides are designed to provide large time delay values within a short length. 17.1 &mu;m &times; 10 &mu;m subwavelength grating (SWG) couplers are employed in order to enable efficient light coupling from and to a fiber. Photonic crystal tapers are implemented at the stripphotonic crystal waveguide interfaces to minimize loss and provide larger time delay values. A large group index of ~28.5 is calculated from the measurement data, thus indicating achievability of time delay larger than 58ps per millimeter length of the delay line within a tuning range of 20nm.
Improvement of Magnetic Characteristic in Spheroidal Graphite Cast Iron (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
CGALmesh (2015)

CGALmesh is the mesh generation software package of the Computational Geometry Algorithm Library (CGAL). It generates isotropic simplicial meshes—surface triangular meshes or volume tetrahedral meshes—from input surfaces, 3D domains, and 3D multidomains, with or without sharp features. The underlying meshing algorithm relies on restricted Delaunay triangulations to approximate domains and surfaces and on Delaunay refinement to ensure both approximation accuracy and mesh quality. CGALmesh provides guarantees on approximation quality and on the size and shape of the mesh elements. It provides four optional mesh optimization algorithms to further improve the mesh quality. A distinctive property of CGALmesh is its high flexibility with respect to the input domain representation. Such a flexibility is achieved through a careful software design, gathering into a single abstract concept, denoted by the oracle, all required interface features between the meshing engine and the input domain. We already provide oracles for domains defined by polyhedral and implicit surfaces.
Studies on the expression of the microtubule-associated protein, tau, during mouse brain development, with newly isolated complementary DNA probes. (1984)

Tau protein is a collection of closely related polypeptides that associate with microtubules in vivo and stimulate their assembly in vitro. Using an affinity-purified antiserum against bovine brain tau protein, we found that the number and amount of tau polypeptides changes dramatically during mouse brain development. The different forms appear to result from changes in tau mRNA since in vitro translation products reflect the qualitative and quantitative changes found in vivo. To study the mRNA and genomic complexity of tau protein, we used tau mRNA, purified from polysomes with tau antiserum, to isolate embryonic mouse tau complementary DNA clones. With these probes we have determined that embryonic tau protein is translated from a 6-kb mRNA that persists throughout brain development.
Improved Glucose Metabolism In Vitro and In Vivo by an Allosteric Monoclonal Antibody That Increases Insulin Receptor Binding Affinity (2014)

Previously we reported studies of XMetA, an agonist antibody to the insulin receptor (INSR). We have now utilized phage display to identify XMetS, a novel monoclonal antibody to the INSR. Biophysical studies demonstrated that XMetS bound to the human and mouse INSR with picomolar affinity. Unlike monoclonal antibody XMetA, XMetS alone had little or no agonist effect on the INSR. However, XMetS was a strong positive allosteric modulator of the INSR that increased the binding affinity for insulin nearly 20-fold. XMetS potentiated insulin-stimulated INSR signaling ∼15-fold or greater including; autophosphorylation of the INSR, phosphorylation of Akt, a major enzyme in the metabolic pathway, and phosphorylation of Erk, a major enzyme in the growth pathway. The enhanced signaling effects of XMetS were more pronounced with Akt than with Erk. In cultured cells, XMetS also enhanced insulin-stimulated glucose transport. In contrast to its effects on the INSR, XMetS did not potentiate IGF-1 activation of the IGF-1 receptor. We studied the effect of XMetS treatment in two mouse models of insulin resistance and diabetes. The first was the diet induced obesity mouse, a hyperinsulinemic, insulin resistant animal, and the second was the multi-low dose streptozotocin/high-fat diet mouse, an insulinopenic, insulin resistant animal. In both models, XMetS normalized fasting blood glucose levels and glucose tolerance. In concert with its ability to potentiate insulin action at the INSR, XMetS reduced insulin and C-peptide levels in both mouse models. XMetS improved the response to exogenous insulin without causing hypoglycemia. These data indicate that an allosteric monoclonal antibody can be generated that markedly enhances the binding affinity of insulin to the INSR. These data also suggest that an INSR monoclonal antibody with these characteristics may have the potential to both improve glucose metabolism in insulinopenic type 2 diabetes mellitus and correct compensatory hyperinsulinism in insulin resistant conditions.
Optical diagnostics for W/O emulsification within impinging flow and right angle mini-channel (2013)

The emulsification is well known for being considered as a solution for improving biodiesel combustion. In this extent, the size of the dispersed droplets is crucial to favour micro-explosions and optimising the combustion. The present mini-channel operates liquid/liquid dispersion at higher flow rates than with usual implementations of minichannels and micro-channels. Due to this particular condition of functioning, the flow enhanced in the mini channel is classified as a high-speed emulsifying one. In this study, the dispersion of water into sunflower oil as a water-in-oil (w/o) emulsion is tested. In such an in-line process, high-shear implies higher velocities at smaller scales, making an optical visualisation difficult. But the light scattering technique enables to detect micro-scaled droplets, at the required high velocities. The proper design and exploitation of a focalised laser beam through a transparent, hydrophobic mini-channel is explained. A focalised laser beam is crossing the mini-channel, dealing with the scattering cross sections of the water droplets. The measurement of the collected beam is successfully matched to the geometrical properties of the emulsion (water fraction and size of inner droplets) through the classical light scattering theoretical basement. The calibration of the collected laser light technique obtained in the straight mini-channel is followed by measurements approaching the high shear rate zone of the cross-flowing mini-channel
Universal Design of Consumer Products: Current Industry Practice and Perceptions (2000)

How and why do some companies successfully practice universal design of their products? Why do other companies not practice universal design, and what might motivate them to adopt it? What are the most effective things that can be done by those on the outside to increase the number of companies successfully practicing universal design? This paper reports results from a three-year study of the practice of universal design in companies providing consumer products and services, which was undertaken to discover the answers to these questions. The study included extensive interviews, a comprehensive survey, and the monitoring of the effects of many of the key facilitation strategies. The key external strategy, although controversial, is that of government regulation requiring the accessibility of products and services. Other important strategies include training and educational programs in universal design and development of market data.
ChemInform Abstract: Enhanced Enantiocontrol in Catalytic Metal Carbene Transformations with Dirhodium(II) Tetrakis(methyl 2‐oxooxazolidin‐4(S)‐carboxylate), Rh2(4S‐meox)4. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Mixed assembly on PCB of wide variety components (MCM-D, SMDs, bare dies) using wire bonding and SMT (2003)

The article describes the process flow of mixed/hybrid assembly module of a MCM-D PLL circuit that exhibiting good electrical performance. The module is a typical example of mixed/hybrid assembly consisting from wire bonding (2 levels of interconnection), mounting of bare dies, SMT on PCB. The main challenge of such type of assemblies is compatibility wire bonding and SMT. Another challenge is 2 levels of wire bonding interconnection. It was done using two type of bonding wires characterizing of different temper. Classical SMT solder reflow process was replaced by more environmentally friendly conductive adhesive glue process. It also helps to decrease thermal exposure down to 150 /spl deg/C. Temperature of 150 /spl deg/C was the highest temperature of thermal treatment this assembly. Relatively light thermal treatment eliminates warping of PCB FR4.
Cryptococcus neoformans Capsular Polysaccharide and Exopolysaccharide Fractions Manifest Physical, Chemical, and Antigenic Differences (2007)

The human pathogenic fungus Cryptococcus neoformans has a large polysaccharide (PS) capsule and releases copious amounts of PS into cultures and infected tissues. The capsular PS is a major virulence factor that can elicit protective antibody responses. PS recovered from culture supernatants has historically provided an ample and convenient source of material for structural and immunological studies. Two major assumptions in such studies are that the structural features of the exopolysaccharide material faithfully mirror those of capsular PS and that the isolation methods do not change PS properties. However, a comparison of exopolysaccharide made by two isolation techniques with capsular PS stripped from cells with gamma radiation or dimethyl sulfoxide revealed significant differences in glycosyl composition, mass, size, charge, viscosity, circular-dichroism spectra, and reactivity with monoclonal antibodies. Our results strongly suggest that exopolysaccharides and capsular PS are structurally different. A noteworthy finding was that PS made by cetyltrimethylammonium bromide precipitation had a larger mass and a different conformation than PS isolated by concentration and filtration, suggesting that the method most commonly used to purify glucuronoxylomannan alters the PS. Hence, the method used to isolate PS can significantly influence the structural and antigenic properties of the product. Our findings have important implications for current views of the relationship between capsular PS and exopolysaccharides, for the generation of PS preparations suitable for immunological studies, and for the formulation of PS-based vaccines for the prevention of cryptococcosis.
Construction of Sidon Spaces With Applications to Coding (2017)

A subspace of a finite extension field is called a Sidon space if the product of any two of its elements is unique up to a scalar multiplier from the base field. Sidon spaces were recently introduced by Bachoc et al. as a means to characterize multiplicative properties of subspaces, and yet no explicit constructions were given. In this paper, several constructions of Sidon spaces are provided. In particular, in some of the constructions the relation between k, the dimension of the Sidon space, and n, the dimension of the ambient extension field, is optimal. These constructions are shown to provide cyclic subspace codes, which are useful tools in network coding schemes. To the best of our knowledge, this constitutes the first set of constructions of nontrivial cyclic subspace codes in which the relation between k and n is polynomial, and in particular, linear. As a result, a conjecture by Trautmann et al. regarding the existence of non-trivial cyclic subspace codes is resolved for most parameters, and multi-orbit cyclic subspace codes are attained, whose cardinality is within a constant factor (close to 1/2) from the sphere-packing bound for subspace codes.
Wideband printed dipole antenna for multiple wireless services (2002)

A coax-fed printed fat dipole backed by a ground plate is presented. The printed dipole with optimum width to length ratio (W/L) of the dipole arm has a wide impedance bandwidth of 75% (VSWR<1.5) and 82% (VSWR<2). This frequency range covers the PCs, IMT-2000, and the ISM band continuously. Antenna parameters for wide bandwidth are investigated and several antenna characteristics are discussed.