gebhart/patrepeval huggingface dataset:
Control of multi-DOF ultrasonic motor using neural network based inverse model (2003)

A multi-DOF ultrasonic motor developed by the authors is capable of generating multi-DOF rotation of a spherical rotor using three orthogonal natural vibrations of a bar-shaped stator. The ultrasonic motor is suitable for making small, light weight and simple multi-DOF motion unit. In the present paper, a control methodology for the multi-DOF ultrasonic motor is proposed and a motion control test using the method is conducted. First, an inverse model of the multi-DOF ultrasonic motor is developed using our prior knowledge in ultrasonic motors and neural network technique in order to deal with the redundancy and non-linearity of driving characteristics. Second, a novel control method using the inverse model is proposed. Then, motion control tests are conducted to confirm the ability of the proposed control method. The results confirm that the rotor can be rotated around arbitrary rotational axis using the inverse model, and that the proposed control method does work successfully.
Comparison of [ 18F]D3FSP([18F]P16-129) and [18F] AV45 in Alzheimer’s Disease (2019)

1457 Objectives: We have synthesized and studied the deuterated N-methyl derivative of Amyvid, [18F]D3FSP ([18F]P-16-129), in a pilot study in participants with Alzheimer’s disease (AD). AV-160, the major metabolite of florbetapir (Amyvid, AV45), is demethylated, with a lower affinity for beta amyloid plaques and the ability to cross the BBB. We hypothesized that [18F]D3FSP would have a higher binding affinity and slower peripheral in vivo metabolism, peripherally. This could improve image contrast or lower the required injected dose.
 Methods: We synthesized [18F]D3FSP at high specific activity (average 2164 ± 506 GBq/micromole). Six subjects with clinically diagnosed (AD, age, mean 60.2 ± 10.2 (SD), range 50-77 (4M), and average mean MMSE 21 ± 4 (SD, range 15-26), received paired 90-minute dynamic scans on a GE Advance PET of 333 ± 47 MBq of [18F]D3FSP and [18F]AV-45 (obtained commercially). Each venous samples for HPLC metabolite analysis were obtained at 5, 20, 45 and 90 minutes, post injection. The parent fraction and the desmethyl metabolites were identified from both [18F]D3FSP and [18F]AV45 scans employing HPLC radio-detection and uv detection by comparison with parent and desmethyl metabolite standards. Quantification included both SUVR (50-70 min) and DVR methods.
 Results: The DVR and SUVR of 43 brain regions, left and right merged, were obtained. The mean global SUVR across all cortical gray matter was 1.59 +/- 0.21 for [18F]AV45 and 1.61 +/- 0.25 for [18F]D3FSP (DVRs were 1.35 +/- 0.14 for AV45 and 1.37 +/- 0.16 for [18F]D3FSP). SUVR and DVR correlated strongly for both tracers (r > 0.9, p 0.96) and slope 1.0. Visual inspection of the AV45 scans met criteria for positivity by AVID established clinical review criteria, although 2 subjects were borderline. There was no evidence that image artifacts or confounds affected quantification of [18F]D3FSP compared to [18F]AV45. Anecdotally, visual review of the [18F]D3FSP and [18F]AV45 showed some moderate differences in image quality and loss of gray-white differentiation consistent with the quantification.
 Conclusions: In this small sample of 6 AD subjects, there were no substantial differences between [18F]D3FSP vs. [18F]AV45 but, 50% of the subjects did have slightly higher global cortical SUVR with [18F]D3FSP vs. [18F]AV45. Although all had a clinical diagnosis of AD, some of the subjects had only moderate quantitative uptake using the [18F]AV45 criteria. Visual inspection suggests [18F]D3FSP vs. [18F]AV45 may have some subtle differences in clinical readings and there may be quantitative differences in some individual cases but a larger population is needed with more severe patients before concluding the potential improved diagnostic value of [18F]D3FSP. Support by Five Eleven Pharma Inc.
Supplementary Figure Legends from Alarmin IL-33 Acts as an Immunoadjuvant to Enhance Antigen-Specific Tumor Immunity (2023)

&lt;p&gt;PDF file - 76KB&lt;/p&gt;
CCD‐Camera Based Optical Beacon Tracking for Virtual and Augmented Reality (1996)

Abstract We introduce a scheme for optical beacon tracking using two CCD‐cameras and LED beacons. Due to the sub‐pixel accuracy of the beacon detection algorithm a very high precision can be achieved so that the tracking method is suitable for augmented reality applications. We describe the assembly of the equipment needed for the whole tracking system, the behavior of LED‐beacons, and how three beacons can be combined to form a 6‐DOF tracker. A report on our accuracy evaluation and its results are given. Furthermore we describe two application prototypes in which the tracker was incorporated and tested.
Distributed universally optimal strategies for interference channels with partial message passing (2009)

In distributed wireless networks, nodes often do not know the topology (network size, connectivity and the channel gains) of the network. Thus, they have to compute their transmission and reception parameters in a distributed fashion. In this paper, we consider that each of the transmitter know the channel gains of all the links that are at-most two-hop distant from it and the receiver knows the channel gains of all the links that are three-hop distant from it in a deterministic interference channel. With this limited information, we find a condition on the network connectivity for which there exist a distributed strategy that can be chosen by the users with partial information about the network state, which achieves the same sum capacity as that achievable by the centralized server that knows all the channel gains. Specifically, distributed decisions are sum-rate optimal only if each connected component is in a one-to-many configuration or a fully-connected configuration. In all other cases of network connectivity, the loss can be arbitrarily large.
Synthesis of Norbornene-Derived Polymers Having Pendant Phenoxyquinones for Photochromism (2001)

ADVERTISEMENT RETURN TO ISSUECommunication to the...Communication to the EditorNEXTSynthesis of Norbornene-Derived Polymers Having Pendant Phenoxyquinones for PhotochromismJong-Man Kim, Hwa-Young Shin, Ki Hong Park, Tae-Ho Kim, Sang Yong Ju, Dong Keun Han, and Kwang-Duk AhnView Author Information Division of Chemical Engineering, College of Engineering, Hanyang University, 17 Haengdang-dong, Seongdong-gu, Seoul 133-791, Korea; Department of Polymer Science and Engineering, Sung Kyun Kwan University, 300 Chunchun-dong, Jangan-gu, Suwon, Kyunggi-do 440-746, Korea; and Electronic Materials and Devices Research Center and Biomaterials Research Center, Korea Institute of Science and Technology, P.O. Box 131, Cheongryang, Seoul 130-650, Korea Cite this: Macromolecules 2001, 34, 13, 4291–4293Publication Date (Web):May 19, 2001Publication History Received4 December 2000Revised10 April 2001Published online19 May 2001Published inissue 1 June 2001https://pubs.acs.org/doi/10.1021/ma002061nhttps://doi.org/10.1021/ma002061nrapid-communicationACS PublicationsCopyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views391Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Copolymers,Irradiation,Monomers,Polymers,Radical polymerization Get e-Alerts
Wireshark for Network Forensics (2022)

This book outlines the advanced features and capabilities of the Wireshark tool to capture and analyze traffic from network-based advanced technologies.
Structural and Chemical Approach toward Understanding the Aqueous Corrosion of Sodium Aluminoborate Glasses (2018)

Despite an ongoing strenuous effort to understand the compositional and structural drivers controlling the chemical durability of oxide glasses, there is still no complete consensus on the basic mechanism of glass dissolution that applies to a wide composition space. One major reason for this problem is the structural complexity contained within the multicomponent silicate glasses chosen for glass corrosion studies. The nonsilicate network polyhedra present in these glasses interact with one another, often in unpredictable ways, by forming a variety of structural associations, for example, Al<sup>[IV]</sup>-B<sup>[III]</sup> and B<sup>[III]</sup>-B<sup>[IV]</sup>, resulting in significant influence on both the structure of the glass network and related macroscopic properties. Likewise, the formation of a variety of next-neighbor linkages, as well as increasingly complex interactions involving Si and differently coordinated next-nearest neighbor cations, is very difficult to decipher experimentally. Consideration of these factors motivates instead a different strategy: that is, the study of a sequence of SiO<sub>2</sub>-free ternary or quaternary glass compositions, whose structures can be unambiguously determined and robustly linked to their corrosion properties. With this aim, the present study is focused on understanding the structural drivers governing the kinetics and mechanism of corrosion of ternary Na<sub>2</sub>O-Al<sub>2</sub>O<sub>3</sub>-B<sub>2</sub>O<sub>3</sub> glasses (in water) over a broad composition space comprising compositions with distinct structural features. It has been shown that the addition of Al<sub>2</sub>O<sub>3</sub> to binary sodium borate glasses decreases their corrosion rate in water and converts their dissolution behavior from congruent to incongruent leading to the formation of six-coordinated alumina, and higher concentration of four-coordinated boron (in comparison to pre-dissolution glasses) in post-dissolution glass samples. The drivers controlling the corrosion kinetics and mechanism in these glasses based on their underlying structure have been elucidated. Some open questions have been proposed which require an extensive analysis of surface chemistry of pre- and post-dissolution samples and will be investigated in our future work.
137 VALIDATION OF PHARMACODYNAMIC MONITORING OF MYCOPHENOLIC ACID (1995)

Langman, L. J.; Lakey, J.; Shapiro, J.; LeGatt, D. F.; Kneteman, N.; Yatscoff, R. W. Author Information
114 Structural insights into the mechanism of homologous recombination (2015)

The recognition and strand exchange process central to homologous recombination (HR) involves structural transitions for both the DNA and the protein filament components. The DNA engaged in the HR ...
Biosensors: Cancer Prognostics by Direct Detection of p53‐Antibodies on Gold Surfaces by Impedance Measurements (Small 13/2012) (2012)

The cover image shows the detection of an antibody by its epitope immobilized through a self-assembled monolayer on a gold surface. The detection is made possible by impedance measurements. The light dots and flashes represent the electrical conductivity through the gold surface, where two different molecules are presented: the blocking molecules to avoid non-specific adsorption and the reactive epitopes. It is observed that the epitopes can be in different configurations to mimic the induced-fit approach, which is carried out by the proximity of the epitope to the reactive site of the antibody. For more information, please read the Full Paper “Cancer Prognostics by Direct Detection of p53-Antibodies on Gold Surfaces by Impedance Measurements” by E. Prats-Alfonso, F. Albericio, and co-workers, beginning on page 2106. Image credit: Gemma Gabriel and Elisabet Prats-Alfonso.
Gelled vs non-gelled phantom material for measurement of temperature rise by the MRI RF-magnetic field (2004)

In this paper we study the magnetic resonance imaging (MRI), eddy currents are induced in the body of the patient by the RF magnetic field. The precession rate of the proton magnetization determines the frequency, which is 64 MHz for 1.5 T static field. The RF-induced currents in the body are concentrated near medical implants, resulting in a localized additional temperature rise.
Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2 (2020)

A consensus virtual screening protocol has been applied to ca. 2000 approved drugs to seek inhibitors of the main protease (M<sup>pro</sup>) of SARS-CoV-2, the virus responsible for COVID-19. 42 drugs emerged as top candidates, and after visual analyses of the predicted structures of their complexes with M<sup>pro</sup>, 17 were chosen for evaluation in a kinetic assay for M<sup>pro</sup> inhibition. Remarkably 14 of the compounds at 100-μM concentration were found to reduce the enzymatic activity and 5 provided IC<sub>50</sub> values below 40 μM: manidipine (4.8 μM), boceprevir (5.4 μM), lercanidipine (16.2 μM), bedaquiline (18.7 μM), and efonidipine (38.5 μM). Structural analyses reveal a common cloverleaf pattern for the binding of the active compounds to the P1, P1', and P2 pockets of M<sup>pro</sup>. Further study of the most active compounds in the context of COVID-19 therapy is warranted, while all of the active compounds may provide a foundation for lead optimization to deliver valuable chemotherapeutics to combat the pandemic.
PHOTO REPAIR AND 3D STRUCTURE FROM FLATBED SCANNERS (2009)

Scanners, 3D reconstruction, photo repair, photometric stereo. We introduce a technique that allows 3D information to be captured from a conventional flatbed scanner. The technique requires no hardware modification and allows untrained users to easily capture 3D datasets. Once captured, these datasets can be used for interactive relighting and enhancement of surface detail on physical objects. We have also found that the method can be used to scan and repair damaged photographs. Since the only 3D structure on these photographs will typically be surface tears and creases, our method provides an accurate procedure for automatically detecting these flaws without any user intervention. Once detected, automatic techniques, such as infilling and texture synthesis, can be leveraged to seamlessly repair such damaged areas. We first present a method that is able to repair damaged photographs with minimal user interaction and then show how we can achieve similar results using a fully automatic process. 1
Matrix isolation photolysis study of tetrazolo[1,5-b]pyridazineDedicated to Professor Dr Z. R. Grabowski and Professor Dr J. Wirz on the occasions of their 75th and 60th birthdays. (2003)

Photolysis (254 nm) of tetrazolo[1,5-b]pyridazine (TP) in 2-methyltetrahydrofuran at 7 K does not produce electron spin resonance absorptions that are usually characteristic of a triplet nitrene. The UV-vis spectrum formed upon photolysis of TP in 2-methyltetrahydrofuran at 77 K is also consistent with the lack of formation of triplet 3-pyridazylnitrene. Photolysis (254 nm) of tetrazolo[1,5-b]pyridazine (TP), i.e., 3-azidopyridazine in an Ar matrix at 16 K produces an infrared spectrum consistent with the formation of Z-cis-1-cyano-3-diazopropene, 1,3,7-triazacyclohepta-1,2,4,6-tetraene, and 3-cyanocyclopropene whose spectra were adequately simulated by density functional theory with a 6-31G* basis set. There is no spectral evidence to support the formation of triplet 3-pyridazylnitrene. Cyclization of the singlet pyridazylnitrene is observed in minute amounts to ultimately produce the ring-expanded 1,3,7-triazacyclohepta-1,2,4,6-tetraene (νNCN = 1981 cm−1). This observation indicates that the earlier vibrational assignment to 1,3,7-triazacyclohepta-1,2,4,6-tetraene in the 2-pyrimidylnitrene system (νNCN = 2045 cm−1) is in error, and should be attributed to the 1972 cm−1 vibrational absorption in the previously recorded spectrum.
France (2011)

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Development of magnetic cores using commercial armorphous thin film for high voltage applications (2013)

Summary form only given. A large toroidal magnetic core for high voltage applications is developed. The toroidal magnetic cores are laminated with amorphous metal films insulated with polyimide film. For easy realization we used Metglas 2605SA1 amorphous film which is widely used in power distribution transformer industry. We tested the small scaled magnetic cores in pulse condition. Based on these results, we made large toroidal magnetic cores and designed an induction voltage adder with three cells.
The glycogen‐binding subunit of protein phosphatase‐1g from rabbit skeletal muscle (1989)

The glycogen-bound form of protein phosphatase-1 (PP-1G) was previously purified as a heterodimer composed of a 37-kDa catalytic (C) subunit and a proteolytically sensitive 103-kDa glycogen-binding (G) subunit [Stråhlfors, P., Hiraga, A. & Cohen, P. (1985) Eur. J. Biochem. 149, 295-303]. In this paper we demonstrate by a variety of criteria that the intact G subunit is a 161-kDa protein, and that the 103-kDa species (now termed G') is itself a product of proteolysis. A second phosphorylation site for cAMP-dependent protein kinase (termed site 2) was identified on the G subunit. The site 2 serine was phosphorylated at a comparable rate to site 1, and near stoichiometric phosphorylation could be achieved in the presence and absence of glycogen. Site 2 was dephosphorylated by PP-1 at a slow rate, whereas site 1 was resistant to autodephosphorylation. PP-1G, as well as the proteolytic activity responsible for degradation of the G subunit, remained tightly associated with glycogen-protein particles during washing with a variety of solvents. The PP-1G holoenzyme was released from glycogen-protein particles by dilution, with a dissociation half point corresponding to about 10 nM PP-1G. Binding experiments with purified PP-1G and glycogen indicated a bimolecular process with Kapp values corresponding to about 8 nM glycogen and 4 nM PP-1G. Binding was not significantly affected by increasing ionic strength to 0.5 M or variation of pH from 6 to 8. The results are consistent with a high-affinity glycogen-binding domain on the G subunit, and indicate that a physiological concentrations of phosphatase and glycogen, PP-1G should be almost entirely bound to glycogen.
A virtual slit for atom optics and nanolithography (1996)

We propose a simple `virtual slit' for atoms based on the position- and velocity-dependent optical pumping of atoms into an undetected internal state. We show how this slit can be used as a nanometre scale, high-contrast tool for atom lithography as well as a subrecoil collimator for atomic beams.
ChemInform Abstract: Hydrogen Evolution Catalyzed by Cobaloximes (2010)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Computer Simulation of a Geomagnetic Substorm (1981)

A global two-dimensional simulation of a substormlike process occurring in Earth's magnetosphere is presented. The results are consistent with an empirical substorm model---the neutral-line model. Specifically, the introduction of a southward inter-planetary magnetic field forms an open magnetosphere. Subsequently, a substorm neutral line forms $\ensuremath{\lesssim}15 {R}_{E}$ in the magnetotail, and plasma sheet thinning and plasma acceleration occur. Eventually the substorm neutral line moves tailward toward its presubstorm position.
Viral protein X reduces the incorporation of mutagenic noncanonical rNTPs during lentivirus reverse transcription in macrophages (2019)

Unlike activated CD4+ T cells, nondividing macrophages have an extremely small dNTP pool, which restricts HIV-1 reverse transcription. However, rNTPs are equally abundant in both of these cell types and reach much higher concentrations than dNTPs. The greater difference in concentration between dNTPs and rNTPs in macrophages results in frequent misincorporation of noncanonical rNTPs during HIV-1 reverse transcription. Here, we tested whether the highly abundant SAM domain- and HD domain-containing protein 1 (SAMHD1) deoxynucleoside triphosphorylase in macrophages is responsible for frequent rNTP incorporation during HIV-1 reverse transcription. We also assessed whether Vpx (viral protein X), an accessory protein of HIV-2 and some simian immunodeficiency virus strains that targets SAMHD1 for proteolytic degradation, can counteract the rNTP incorporation. Results from biochemical simulation of HIV-1 reverse transcriptase-mediated DNA synthesis confirmed that rNTP incorporation is reduced under Vpx-mediated dNTP elevation. Using HIV-1 vector, we further demonstrated that dNTP pool elevation by Vpx or deoxynucleosides in human primary monocyte-derived macrophages reduces noncanonical rNTP incorporation during HIV-1 reverse transcription, an outcome similarly observed with the infectious HIV-1 89.6 strain. Furthermore, the simian immunodeficiency virus mac239 strain, encoding Vpx, displayed a much lower level of rNTP incorporation than its ΔVpx mutant in macrophages. Finally, the amount of rNMPs incorporated in HIV-1 proviral DNAs remained unchanged for ∼2 weeks in macrophages. These findings suggest that noncanonical rNTP incorporation is regulated by SAMHD1 in macrophages, whereas rNMPs incorporated in HIV-1 proviral DNA remain unrepaired. This suggests a potential long-term DNA damage impact of SAMHD1-mediated rNTP incorporation in macrophages.
Polyimide/Carbon Nanotube Composite Films for Electrostatic Charge Mitigation (2004)

Low color, space environmentally durable polymeric films with sufficient electrical conductivity to mitigate electrostatic charge build-up have been under investigation as part of a materials development activity. In the work described herein, single-walled carbon nanotubes (SWNT) solutions were dispersed in solutions of a novel ionomer in N,N-dimethylacetamide resulting in homogenous suspensions or quasi-solutions. The ionomer was used to aid in the dispersal of SWNTs in to a soluble, low color space environmentally durable polyimide. The use of the ionomer as a dispersant enabled the nanotubes to be dispersed at loading levels up to 3 weight % in a polyimide solution without visual agglomeration. The films were further characterized for their electrical and mechanical properties.