gebhart/patrepeval huggingface dataset:
Implementations of smart pixels for optoelectronic processors and interconnection systems. I. Optoelectronic gate technology (1993)

For part II see ibid., vol. 11, no. 10, pp. 1670-1680 (Oct. 1993). Several of the common approaches to smart pixel technology, including smart pixels based on optoelectronic integrated circuits and self-electrooptic effect devices (SEEDs), are studied. An optoelectronic NOR gate pixel consisting of an output laser diode, two input photodetectors, and a transistor circuit is analyzed for the purpose of investigating overall two-dimensional (2-D) interconnection and processing system performance. The major pixel performance issues are examined. The results show that the optoelectronic logic gate has the advantages of low noise (typically approximately -35 dBm), high bandwidth (>1 GHz), and low temperature sensitivity, while its power dissipation is about 5 mW, resulting in a moderate pixel packing density of 200/cm/sup 2/ for a total chip power dissipation of 1 W/cm/sup 2/.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
An Adaptive MIMO-OFDMA Relay System (2012)

We consider multi-input multi-output (MIMO) antennas relay systems under time-varying channels and propose a joint relay, antenna, subband, and MIMO transmission mode adaptation scheme which enables antenna selection to exploit channel state information (CSI) at the beginning of transmission and switch to space-frequency block coding (SFBC) when CSI becomes outdated. Moreover, we propose temporal power and bit loading for the cascaded source-relay-destination link with/without inter-hop power allocation to further enhance the system performance.
A Novel Two-Stage Detection Scheme for UWB Signal Acquisition (2010)

This paper proposes a novel detection scheme based on multiple correlator outputs to enhance the detection performance in ultra-wideband (UWB) signal acquisition. Due to the rich multipath of UWB channels, the signal energy spreads over multiple correlator outputs, which makes each correlator output have only a portion of the signal energy, and thus, degrades the detection performance of the conventional scheme where a single correlator output is used as the decision variable for detection. In the proposed two-stage detection scheme, the decision variable is formed by combining multiple correlator outputs, making it possible to collect the signal energy spread by the multipath. Simulation results show that the proposed scheme can provide a better detection performance over the conventional scheme in various UWB channel environments.
Zoran Drvenkar nos pide perdón... (2011)

The influence has been studied of the membrane and solution composition on the response of H(+)-ISEs with plasticized polymer and liquid membranes based on the neutral carriers N,N-dioctylaniline and tridecylamine in association with trioctyloxybenzene sulphonic acid. It is shown that the extraction processes at the membrane/solution interface exert the main effect on the response limits by inducing essential changes in the activity of potential-determining ions in the membrane. At low pH, the amine extraction of acids followed by neutralization (free amines binding in ion-pairs) is the relevant process, while at high Ph it is the extraction of metal cations with amine salts of a lipophilic acid, with the consequent displacement of amine from the salts. Equations are suggested to represent the interphase potential of the H(+)-ISE membranes with allowance for these extraction processes. The experimental electrode responses of both liquid and polymer membranes are shown to be well described by the equations for the interphase potential, thus indicating its dominant contribution to the membrane potential.
Search for long-lived heavy neutral leptons with displaced vertices in proton-proton collisions at $$ \sqrt{\mathrm{s}} $$ =13 TeV (2022)

A bstract A search for heavy neutral leptons (HNLs), the right-handed Dirac or Majorana neutrinos, is performed in final states with three charged leptons (electrons or muons) using proton-proton collision data collected by the CMS experiment at $$ \sqrt{s} $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msqrt> <mml:mi>s</mml:mi> </mml:msqrt> </mml:math> = 13 TeV at the CERN LHC. The data correspond to an integrated luminosity of 138 fb − 1 . The HNLs could be produced through mixing with standard model neutrinos ν . For small values of the HNL mass ( &lt; 20 GeV) and the square of the HNL- ν mixing parameter (10 − 7 –10 − 2 ), the decay length of these particles can be large enough so that the secondary vertex of the HNL decay can be resolved with the CMS silicon tracker. The selected final state consists of one lepton emerging from the primary proton-proton collision vertex, and two leptons forming a displaced, secondary vertex. No significant deviations from the standard model expectations are observed, and constraints are obtained on the HNL mass and coupling strength parameters, excluding previously unexplored regions of parameter space in the mass range 1–20 GeV and squared mixing parameter values as low as 10 − 7 .
Endogenous opioid system in developing normal and jimpy oligodendrocytes: ? and ? opioid receptors mediate differential mitogenic and growth responses (1998)

The early development of both neurons and neuroglia may be modulated by signaling through opioid mediated pathways. Neurons and astroglia not only express specific types of opiate receptors, but also respond functionally to opioids with altered rates of proliferation and growth. The present study was undertaken to determine if opioids also modulate development of the other major CNS macroglial cell, the oligodendrocyte (OL). Using well-characterized polyclonal antibodies specific for delta-, kappa-, and mu-opiate receptors, OLs grown in vitro were shown to express mu-receptors at a very immature stage prior to expression of kappa-receptors. This developmentally regulated sequence differs from the pattern of expression in neurons and astroglia. delta-receptors are apparently absent from cultured OLs. OLs also have physiologic responses to selective mu- and kappa-receptor agonists and antagonists. Exposure of relatively immature O4+ OLs to the mu-receptor agonist PL017 [H-Tyr-Pro-Phe(N-Me)-D-Pro-NH2] resulted in a significant enhancement in the rate of DNA synthesis. This effect, which was not observed in more mature MBP+ OLs, was entirely blocked by the antagonist naloxone. Although the kappa-receptor pathway appeared to be uninvolved in controlling proliferation, the kappa-receptor antagonist nor-binaltorphimine significantly increased the size of myelin-like membranes produced by the cultured OLs. Interestingly, OLs derived from the jimpy mouse, a mutant characterized by an almost complete lack of CNS myelin and premature death of OLs, were found to be deficient in kappa-opiate receptors. Our findings clearly show that OLs not only express specific opiate receptors, but also respond to changes in their level of stimulation in ways that could profoundly impact nervous system morphology and function. If opiate receptors are expressed by OLs in vivo, their pharmacological manipulation might provide a novel pathway for modulating OL and myelin production both during development and in demyelinated conditions.
A bulk silicon micromachined structure for gas microdischarge-based detection of beta-particles (2008)

"This paper describes two Si micromachined structures for sensing beta-particles. The basic device (the micro-detector) includes a square silicon cathode surrounded by a concentric anode, and is formed by stacks of glass and Si wafers. Incident beta-particles ionize the gas encapsulated between the electrodes, resulting in an avalanche current pulse or 'count'. It is shown experimentally that devices with 8 x 8 mm2 footprint can detect radiation in the proximity of sealed sources, such as 90Sr and 204Tl with 0.1-1.0 uCi strengths. The sensitivity (cpm mRad[?]1 h) of the micromachined device is comparable to that of commercial radiation detectors, but substantially superior when normalized to the detector volume, which is about 0.06% of the conventional detectors. An extension of the basic device, the stacked micro-detector, consists of a two-tiered arrangement of cavities separated by a thin glass intercavity attenuator that is intended to provide controlled energy absorption. Higher energy particles are detected in both cavities, while lower energy particles are detected in the first cavity and subsequently absorbed by the intercavity attenuator. This can provide initial assessment of the incident radiation without adding significant complexity to the system. Preliminary experimental validation is performed by comparing the device response to 204Tl and 90Sr."
Cleavage of phosphorothioate-substituted DNA by restriction endonucleases. (1984)

M13 RF DNA was synthesized in vitro in the presence of various single deoxynucleoside 5'-O-(1-thiotriphosphate) phosphorothioate analogues, and the three other appropriate deoxynucleoside triphosphates using a M13 (+)-single-stranded template, Escherichia coli DNA polymerase I and T4 DNA ligase. The resulting DNAs contained various restriction endonuclease recognition sequences which had been modified at their cleavage points in the (-)-strand by phosphorothioate substitution. The behavior of the restriction enzymes AvaI, BamHI, EcoRI, HindIII, and SalI towards these substituted DNAs was investigated. EcoRI, BamHI, and HindIII were found to cleave appropriate phosphorothioate-substituted DNA at a reduced rate compared to normal M13 RF DNA, and by a two-step process in which all of the DNA is converted to an isolable intermediate nicked molecule containing a specific discontinuity at the respective recognition site presumably in the (+)-strand. By contrast, SalI cleaved substituted DNA effectively without the intermediacy of a nicked form. AvaI, however, is only capable of cleaving the unsubstituted (+)-strand in appropriately modified DNA.
Microstructured optical fiber devices (2001)

We present several applications of microstructured optical fibers and study their modal characteristics by using Bragg gratings inscribed into photosensitive core regions designed into the air-silica microstructure. The unique characteristics revealed in these studies enable a number of functionalities including tunability and enhanced nonlinearity that provide a platform for fiber device applications. We discuss experimental and numerical tools that allow characterization of the modes of the fibers.
Development of a test rig to evaluate the performance of Front-End Accessory Drive systems (2020)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;The increased adoption of downsized engines along with higher electrical demand is generating a challenge to the Front-End Accessory Drive (FEAD) system functioning and validation. One alternative to speed up the validation of potential design solutions is the in-vehicle experimental tests approach. Nevertheless, experimental data collection during in-vehicle FEAD evaluation imposes some challenges due to, for instance, packaging space constraints and sample rate required to capture the dynamic events during vehicle operation, among others. In order to overcome this limitation, the objective of this research is focused in the development of a customized test rig that emulates FEAD layout of an actual automobile in a simulated operating condition. This equipment could contribute in research studies focusing in critical performance parameters, allowing complete data acquisition and evaluation of potential design trade-offs that could maximize overall performance of the system, as the test rig could also allow the study of the impact of different layouts or operational configurations in the overall system efficiency. Therefore, the test rig design intent is to have a configurable layout that can be fully adjusted and instrumented. It will enable data acquisition and analysis of relevant variables such as motoring and resistive torques, hub loads, belt span vibration levels, among others. Specially those variables that are limited due to packaging constraints during invehicle assessment could be more easily monitored in test rig setup. Moreover, the test rig layout could be adapted to test different types of alternator pulleys, belt tensioners or belt setup, contributing to a proper correlation with in-vehicle assessment. Results obtained in a case study are presented in this paper, demonstrating the functional evaluation of the test rig and preliminary correlation data between in-vehicle testing and test rig monitored variables. Ultimately, benefits of the FEAD test rig are related to a significant reduction in the development time and number of prototype iterations during the evaluation of a real system application.&lt;/div&gt;&lt;/div&gt;
Isolation of candidate tumor suppressor genes for small cell lung cancer (SCLC) from human chromosome 3p21.3 (1994)

Lung cancer is the leading cause of cancer related deaths in the United States. SCLC tumors frequently display deletions on the short arm of chromosome 3 suggesting the existence of a tumor suppressor gene in this region. The region 3p21.3 is one of the common regions of deletions in lung cancer as shown by loss of heterozygosity studies and deletion mapping data and more recently by occurrence of several homozygous deletions in the same region. In our laboratory we have discovered 3 overlapping homozygous deletions in SCLC at 3p21.3. The region has been covered in YAC, p1 and cosmid contigs. Here we describe the isolation, characterization and mutational analysis of several candidate genes for SCLC in the homozygously deleted region at 3p21.3.
A Large Deformation Diffeomorphic Approach to Registration of CLARITY Images via Mutual Information (2016)

CLARITY is a method for converting biological tissues into translucent and porous hydrogel-tissue hybrids. This facilitates interrogation with light sheet microscopy and penetration of molecular probes while avoiding physical slicing. In this work, we develop a pipeline for registering CLARIfied mouse brains to an annotated brain atlas. Due to the novelty of this microscopy technique it is impractical to use absolute intensity values to align these images to existing standard atlases. Thus we adopt a large deformation diffeomorphic approach for registering images via mutual information matching. Furthermore we show how a cascaded multi-resolution approach can improve registration quality while reducing algorithm run time. As acquired image volumes were over a terabyte in size, they were far too large for work on personal computers. Therefore the NeuroData computational infrastructure was deployed for multi-resolution storage and visualization of these images and aligned annotations on the web.
An Effective Heterogeneous Catalyst from Waste Material for the Biodiesel Production (2014)

The aim of this study was to develop an environmentally benign catalyst from natural waste material for the transesterification of vegetable oils. An ABO 3 perovskite type metal oxide based robust catalyst was developed using egg shell and evaluated for effective conversion of vegetable oil to biodiesel.
Frequency cavity pulling induced by a single semiconducting artificial atom (2013)

An artificial atom coupled to a resonator of narrower emission linewidth opens a whole new field for quantum electrodynamics : we investigate such regime and evidence spectacular cavity pulling induced by a single quantum dot.
Adaptive Sensitivity / Intelligent Scan Imaging Sensor Chips (1988)

ABSTRACT CMOS VLSI imaging sensors are described, which employ a novel approach to image acquisition and processing. Principles of biological visual systems, such as adaptation and selective attention, are applied to achieve a high performance imaging system. The Adaptive Sensitivity mechanism enables the acquisition of extremely wide dynamic range, much wider than that of conventional semicon­ ductor sensors, while preserving image details and while dynamically adapting to the image contents. The Intelligent Scan mechanism filters in only the areas of interest, thus reducing the amount of transmitted visual data in an intelligent, image-dependent, adaptive manner, The sensor are complemented with an image processing system, described in a companion paper. 1. INTRODUCTION The principles of organization of biological vision systems provide a most valuable inspiration to the design and construction of intelligent technological vision systems. Consider the fundamental task of image acquisition with high resolution over wide field-of-view. Man-made visual systems, even while employing the most powerful available supercomputers or parallel processors, cannot acquire and manipulate on-line the bit rate of 109 bit per second necessary under the circumstances [1, 2, 3], Yet, biological systems with very limited resources, comprising slow components operating on a time scale of milliseconds, can process this enormous bit rate, and are more than capable of multidimensional pro­ cessing in this environment.We seek to gain some insight into these mechanisms, in order to better design efficient visual data acquisition and processing systems. In this paper we focus on two relatively well understood mechan­ isms of collection and selection of visual data, namely Adaptive Sensitivity combining nonlinear pro­ cessing and multilevel feedback loops, and selective acquisition and processing implementing a non- uniform scheme of computational resources allocation, and outline the design of a family of VLSI based sensors which exploit these biological principles of organization [4, 5, 6, 7],
Is palliative care feasible within respiratory disease models? A multi-site action research approach (2014)

The importance of embracing a palliative care approach for people with advanced respiratory disease is acknowledged in the literature and health policy but there is a lack evidence-based models of care. This study aimed to devise, implement and evaluate palliative care responses for patients with advanced respiratory disease. The multi-site action research project used mixed methods data collection strategies including qualitative interviews with patients and families, expert focus groups and quantitative methods such as education surveys, evaluation and chart audits. Study findings demonstrate that palliative care interventions can be implemented within respiratory services for those patients with advanced disease. The study methodology of action research ensured that all key stakeholders in the service delivery across several sites contributed to sustainable organisational change which delivered measurable care improvements for patients throughout the research process. Interventions that have developed include: shared training and education across sites, multi-disciplinary team meetings, pulmonary rehabilitation session on advanced care planning, end of life care reviews, priority review clinics, supportive home visits and the development of a respiratory palliative care pathway for patients. Palliative care interventions are feasible within care delivery models for patients with advanced respiratory disease. Referral links and a care pathway between hospital and hospice settings are at the cornerstone of this care delivery model. The key to developing appropriate models of care is in the collaboration between respiratory and specialist palliative care teams.
Femtosecond Solitary Pulses in Solid State Lasers (1992)

The third-order nonlinear optical susceptibility χ (3) accounts for a great variety of physical processes in nonlinear optics. 1 For the generation and propagation of ultrashort optical pulses the intensity-dependent refractive index n = n 0 + n 2 I is of particular importance, where n 2 ( ω ) ~ χ (3) ( ω ,– ω , ω ). If the frequency dependence of n 2 ( ω ) is negligible in a broad frequency region, i.e. the main contributions to χ (3) ( ω ,– ω , ω ) are nonresonant, the change in the refractive index follows instantaneously the variation of the intensity of the electromagnetic radiation. Consequently, the carrier frequency and, in the case of free propagation (no waveguiding), the spatial intensity distribution of an intense light pulse are subject to ultrafast modulation (self-phase modulation and time-dependent self-focusing) when propagating through transparent optical media.
Biodegradable Poly(ester) Urethane Acrylate Resins for Digital Light Processing: From Polymer Synthesis to 3D Printed Tissue Engineering Constructs (2020)

Digital light processing (DLP) is one of the most accurate and fastest additive manufacturingtechnologies to produce a variety of products, from patient-customized biomedical implants toconsumer goods; however, DLP’s use in tissue engineering is limited largely due to a lack ofbiodegradable resins. Herein, a library of biodegradable urethane acrylate-capped poly(esters)(with variations in molecular weight) is investigated as the basis for a DLP printable ink fortissue engineering. The synthesized oligomers show good printability in a DLP resin, capableof creating complex structures with mechanical properties matching those of medium-softtissues (1–3 MPa). While fabricated films from different molecular weight resins showed fewdifferences in surface topology, wettability, and protein adsorption, the adhesion and metabolicactivity of L929 and human dermal fibroblasts (HDFs) were significantly different: resins fromhigher molecular weight oligomers provided greater cell adhesion and metabolic activity. Theseprintable and biodegradable resins show the importance of oligomer molecular weight onscaffold properties, and facilitate the printing of elastomeric customizable scaffolds for a varietyof tissue engineering applications.
Modeling of Reduced Surface Field Laterally Diffused Metal Oxide Semiconductor for Accurate Prediction of Junction Condition on Device Characteristics (2011)

In this paper, an accurate model of resistive drift region in laterally diffused metal oxide semiconductor (LDMOS) is presented. We have improved the dynamically varying depletion width model at the drift/substrate junction, by considering both the drain and substrate bias effects. The both bias condition causes the resistance modification of the high resistive drift region for the reduced-surface-field structure (RESURF). In addition, new expansion-effect model is developed by considering the substrate bias effect. The developed models have been implemented into Hiroshima University starc insulated gate field effect transistor model for high voltage (HiSIM-HV) and it is proved that the models reproduce measured direct current (DC) characteristics for the wide variety of the substrate bias variation.
RoSCAR (2014)

In this paper, we present the development of a low-cost, high-performance mobile robot platform for educational and research use called RoSCAR. The platform is based on a 1/10-scale short track race car, integrated with an on-board desktop-class computer, odometry, and RGB-D sensing. As part of an experimental robotics course, three student teams used RoSCAR to compete in a race around a 200 m indoor track. Students demonstrated reliable lane tracking and attained average lap speeds of up to 5.7 m/s (equivalent to 202 km/h at full scale). We are currently investigating the viability of a regional robotics competition centered around this concept.