gebhart/patrepeval huggingface dataset:
DATA COMMUNICATION WITH REMOTE SENSORS USING TWO-WAY PAGING TECHNOLOGY (2000)

This project, categorized as a Product Test, involved the system development and testing of a communication device based upon the ReFLEX Narrowband PCS technology commonly used in two-way pagers. The pager-based communication device was tested with three different remote sensors in the Boston Metropolitan area with assistance and support from the Massachusetts Highway Department. This product is cost effective for transmitting data from Highway Performance Monitoring System sites, and in event-based data transmissions such as incidents, weather, equipment failure, etc. It can be a cost-effective alternative in typical ITS application in situations when traditional methods such as telephone, spread-spectrum or cellular either are technical infeasible or have high installation costs
Arterial Wall Imaging: Evaluation with 16-Section Multidetector CT in Blood Vessel Phantoms and ex Vivo Coronary Arteries (2006)

Determination of composition of individual plaques from attenuation values can be more challenging because of overlapping values for different tissue types.
Inverse polarity techniques for high-speed/low-power multipliers (1999)

Article Free Access Share on Inverse polarity techniques for high-speed/low-power multipliers Authors: Pascal C. H. Meier ECE Dept, Carnegie Mellon Univ., 5000 Forbes Ave., Pittsburgh, PA ECE Dept, Carnegie Mellon Univ., 5000 Forbes Ave., Pittsburgh, PAView Profile , Rob A. Rutenbar ECE Dept, Carnegie Mellon Univ., 5000 Forbes Ave., Pittsburgh, PA ECE Dept, Carnegie Mellon Univ., 5000 Forbes Ave., Pittsburgh, PAView Profile , L. Richard Carley ECE Dept, Carnegie Mellon Univ., 5000 Forbes Ave., Pittsburgh, PA ECE Dept, Carnegie Mellon Univ., 5000 Forbes Ave., Pittsburgh, PAView Profile Authors Info & Claims ISLPED '99: Proceedings of the 1999 international symposium on Low power electronics and designAugust 1999Pages 264–266https://doi.org/10.1145/313817.313942Published:17 August 1999Publication History 6citation200DownloadsMetricsTotal Citations6Total Downloads200Last 12 Months10Last 6 weeks3 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Publisher SiteeReaderPDF
IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV (2013)

The progressive depletion of quiescent "bystander" CD4 T cells, which are nonpermissive to HIV infection, is a principal driver of the acquired immunodeficiency syndrome (AIDS). These cells undergo abortive infection characterized by the cytosolic accumulation of incomplete HIV reverse transcripts. These viral DNAs are sensed by an unidentified host sensor that triggers an innate immune response, leading to caspase-1 activation and pyroptosis. Using unbiased proteomic and targeted biochemical approaches, as well as two independent methods of lentiviral short hairpin RNA-mediated gene knockdown in primary CD4 T cells, we identify interferon-γ-inducible protein 16 (IFI16) as a host DNA sensor required for CD4 T cell death due to abortive HIV infection. These findings provide insights into a key host pathway that plays a central role in CD4 T cell depletion during disease progression to AIDS.
PERFORMANCE EVALUATION OF NDOR MOUNTABLE CURBS. FINAL REPORT (1994)

Three commonly used Nebraska Department of Roads (NDOR) mountable curbs were investigated for relative safety through a combination of full-scale testing and computer simulation using the Highway-Vehicle-Object-Simulation-Model (HVOSM). The curbs that were investigated included one 4-in. (10.16-cm) and two 6-in. (15.25-cm) mountable curbs. The applicability of the model was evaluated with 23 full-scale tests, including thirteen tests on a 4-in. (10.16-cm) wedge shaped curb, two tests on a 6-in. (15.25-cm) wedge shaped curb and eight tests on a 6-in. (15.25-cm) Type I Mountable curb. The crash tests were conducted with 1800 and 4500-lb (816.5 and 2041.2-kg) test vehicles at impact speeds of 45, 50, and 55 mph (72.4, 80.5, and 88.5 km/h) and impact angles of 5, 12.5, and 20 degrees. HVOSM was first validated against all 23 full-scale crash tests and then used to predict vehicle behaviors at alternate impact conditions. The simulation and crash test program have shown that Nebraska's mountable curbs do not have a potential for causing loss of vehicle control or vehicle destabilization when impacted in a tracking condition. Although the 6-in. (15.25 cm) mountable curbs were found to cause slightly higher vehicle motions, the differences do not appear significant enough to indicate a reduced safety performance for these curbs. Also, it was determined that the performance of W-beam guardrail can be adversely affected when used in conjunction with roadside curbs. Additionally, through a limited simulation effort of non-tracking impacts, it was determined that these curb types may be traversable over a wide range of vehicle orientations and may not be a significant cause of vehicle rollovers.
Supplemental Figure 3 from A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors (2023)

&lt;p&gt;Detection of tumor targeting by in vivo imaging (fluorescent intensity, FLI)of CEA TCB formats having bivalent or monovalent binding to CEA and directly labeled with Alexa647.&lt;/p&gt;
In vivodiffuse reflectance micro-spectroscopy for correction of Raman depth profiles acquired on skin (2016)

Confocal Raman microspectroscopy is a relevant and useful tool to perform in vivo diagnosis of cutaneous tissues noninvasively and without labeling. This optical technique provides in-depth molecular and conformational characterization of skin. Unfortunately, spectral distortions occur due to elastic scattering. Our objective is to correct the attenuation of in-depth Raman peaks intensity by considering elastic scattering in biological tissues. In this purpose, a correction model was constructed using skin scattering properties as parameters thus enabling quantitative analysis. The work presented here is a technique of <i>in vivo</i> Diffuse Reflectance Micro-Spectroscopy called Micro-DRS. It achieves optical properties characterization in the skin layers probed by Raman microspectroscopy. The Micro-DRS setup can easily be coupled to a confocal Raman micro-probe to perform simultaneous measurements. Thanks to Monte Carlo simulations and experimental results obtained on homemade solid phantoms mimicking skin optical properties, we show that it is possible to measure the absorption coefficient &mu;<sub>a</sub>, the reduced scattering coefficient &mu;<sub>s</sub>', the scattering coefficient &mu;<sub>s</sub> and the anisotropy of scattering <i>g</i> with this new apparatus. The measured scattering properties can be used subsequently as parameters in our correction model. Coupled to a Raman micro-spectrometer, Micro-DRS enables a quantitative analysis when tracking drug penetration through skin and it can be used independently to provide additional diagnosing criterions.
An efficient bi-layer intumescent paint metal laminate fire barrier for various substrates: Extension to other application (2021)

Different types of passive fireproofing materials exist such as intumescent paints. Our approach was to modify the design the material instead of changing the formulations. By combining two concepts namely intumescence and delamination, and adjustable design, new effective fire barrier was developed to protect composites. It was evaluated using a burn-through fire scenario (heat flux of 116 kW/m2 and temperature of flame of 1100 °C). The fire barrier revealed to provide fire protection to the composite and stabilized the temperature at the backside of the composite plate under 200 °C. Characterisations (cross-section observations, expansion measurements, etc.) were carried out on the samples and a mechanism of action was proposed.
Spatial Bias and Right Hemisphere Function: Sex-Specific Changes with Aging (2011)

Patterns of cerebral asymmetry related to visuospatial functions may change with age. The typical leftward bias on a line bisection task may reflect cerebral asymmetry. With age, such leftward bias decreases. This study demonstrated that the age-related decrease of leftward bias may actually be sex-specific. In addition, previous research suggests that young adults' deviation in line bisection may reflect asymmetric hemispheric activation of perceptual-attentional "where" spatial systems, rather than motor-intentional "aiming" spatial systems; thus, we specifically fractionated "where" and "aiming" bias of men and women ranging in age from 22 to 93 years old. We observed that older men produced greater rightward line bisection errors, of primarily "where" spatial character. However, women's errors remained leftward biased, and did not significantly change with age. "Where" spatial systems may be linked to cortico-cortical processing networks involving the posterior part of the dorsal visuospatial processing stream. Thus, the current results are consistent with the conclusion that reduced right dorsal spatial activity in aging may occur in the male, but not female, adult spatial system development.
On the acoustical design of the ears of flue organ pipes (2004)

Application of the ears to the flue organ pipe is one of the important voicing techniques. Ears are the projections on both sides of the pipe mouth. Organ builders say the ears make not only the sound lower and darker, but also the buildup of tone smoother and quicker. The aim of this research is to confirm their recognitions and make the causes clear. For that purpose, we made acoustical and flow measurements (measurement of the velocity profiles at the mouth) with model pipes. As a result, we could confirm the recognition of the organ builders. In addition, our experiments indicate a slight increase in the blowing pressure in the foot and an increase in the inharmonicity of the pipe eigenmodes. The ear reduces the maximum jet velocity but keeps the characteristic profiles. In some cases, the profiles move as a whole more inside of the pipe. Recent acoustic measurements (eigenmodes of the pipe resonator and of the mouth tone, attack transient and stationary spectrum) on real organ pipes with ears of different heights will be also reported at the meeting.
Transition-metal complexes of dithiooxamide ligands. Vibrational fine structure in the electronic spectra of symmetrically N,N'-disubstituted dithiooxamides and their divalent nickel ion complexes (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTransition-metal complexes of dithiooxamide ligands. Vibrational fine structure in the electronic spectra of symmetrically N,N'-disubstituted dithiooxamides and their divalent nickel ion complexesMichael R. Green, Nusrallah Jubran, Bruce E. Bursten, and Daryle H. BuschCite this: Inorg. Chem. 1987, 26, 14, 2326–2332Publication Date (Print):July 15, 1987Publication History Published online1 May 2002Published inissue 15 July 1987https://pubs.acs.org/doi/10.1021/ic00261a032https://doi.org/10.1021/ic00261a032research-articleACS PublicationsRequest reuse permissionsArticle Views330Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Clinical results of percutaneous pelvic surgery. Computer assisted surgery using ultrasound compared to standard fluoroscopy (2001)

This study presents early results of clinical experience with the application of Computer Assisted Surgery (CAS) to percutaneous iliosacral screwing, with comparison to a historical series of patients treated using percutaneous fluoroscopy. Four patients were instrumented using a CAS system, with 10 screws being inserted. Thirty patients were treated by percutaneous fluoroscopic screwing, with 51 screws being inserted. The follow-up assessment included the following criteria; operative time, parameters of radiation exposure, neurological examination, screw placement evaluation on CT-scan, antalgic drug consumption, pain, Majeed grading, and loosening of implants. In the CAS group, the average radiation time was 0.35 min per patient and 0.14 min per screw. No trajectories outside the bone and no postoperative neurological deficits were found. In the fluoroscopic group, the average radiation time was 1.03 min per patient and 0.6 min per screw. Twelve screws had outside-bone trajectories, and iatrogenic neurological deficits were found in seven patients. The average operative time was 50 min in the CAS group and 35 min in the fluoroscopic group. The present CAS technique shows better placement of iliosacral screws, with no outside-bone trajectories and lower radiation exposure.
<title>Langmuir films of amino acid-modified diacetylenes as organic templates for biomimetic mineralization</title> (1995)

Amino-acid modified diacetylenes were used as organic templates for controlled biomineralization. Macromolecular changes in the monolayers have been observed upon application of pressure or polymerization. The degree of film compression and film polymerization influenced calcium carbonate polymorph selectivity. The desired optimization of the physical properties of the biomineral product is approached via structural control of the organic monolayer.
Bladder Uptake of Liposomes after Intravesical Administration Occurs by Endocytosis (2015)

Liposomes have been used therapeutically and as a local drug delivery system in the bladder. However, the exact mechanism for the uptake of liposomes by bladder cells is unclear. In the present study, we investigated the role of endocytosis in the uptake of liposomes by cultured human UROtsa cells of urothelium and rat bladder. UROtsa cells were incubated in serum-free media with liposomes containing colloidal gold particles for 2 h either at 37°C or at 4°C. Transmission Electron Microscopy (TEM) images of cells incubated at 37°C found endocytic vesicles containing gold inside the cells. In contrast, only extracellular binding was noticed in cells incubated with liposomes at 4°C. Absence of liposome internalization at 4°C indicates the need of energy dependent endocytosis as the primary mechanism of entry of liposomes into the urothelium. Flow cytometry analysis revealed that the uptake of liposomes at 37°C occurs via clathrin mediated endocytosis. Based on these observations, we propose that clathrin mediated endocytosis is the main route of entry for liposomes into the urothelial layer of the bladder and the findings here support the usefulness of liposomes in intravesical drug delivery.
Telmisartan But Not Valsartan Increases Caloric Expenditure and Protects Against Weight Gain and Hepatic Steatosis (2006)

The potential effects of angiotensin II receptor blockers (ARBs) on adipose tissue biology and body weight are of considerable interest, because these agents are frequently used to treat hypertension in patients who are prone to visceral obesity, the metabolic syndrome, and diabetes. In rats fed a high-fat, high-carbohydrate diet, we compared the effects of 2 ARBs, telmisartan and valsartan, on body weight, food intake, energy expenditure, fat accumulation, fat cell size, and hepatic triglyceride levels. Telmisartan, but not valsartan, promoted increases in caloric expenditure and protected against dietary-induced weight gain. In the telmisartan-treated rats, absolute food intake, but not food intake adjusted for body weight, was lower than in valsartan-treated rats or controls. Telmisartan reduced the accumulation of visceral fat and decreased adipocyte size to a much greater extent than valsartan and was also associated with a significant reduction in hepatic triglyceride levels. Moreover, telmisartan, but not valsartan, increased the expression of both nuclear-encoded and mitochondrial-encoded genes in skeletal muscle known to play important roles in mitochondrial energy metabolism. Thus, in addition to a class effect of ARBs in modulating adipocyte size, these findings raise the possibility that certain molecules, like telmisartan, may have a particularly strong impact on fat cell volume and fat accumulation, as well as distinctive effects on energy metabolism, that may help protect against dietary-induced visceral obesity and weight gain.
Factors affecting pregnancy outcomes in young women treated with fertility-preserving therapy for well-differentiated endometrial cancer or atypical endometrial hyperplasia (2016)

We identified three factors considered to affect pregnancy establishment following conservative treatment with MPA: recurrence, endometrial thickness during ovulation, and the age of the pregnancy permission. Introduction of infertility treatment including assisted reproductive technology (ART) soon after achieving tumor disappearance by MPA would therefore be beneficial for patients with disease recurrence, thin endometrium, or a higher age of pregnancy permission.
Streptomyces as Microbial Chassis for Heterologous Protein Expression (2021)

Heterologous production of recombinant proteins is gaining increasing interest in biotechnology with respect to productivity, scalability, and wide applicability. The members of genus <i>Streptomyces</i> have been proposed as remarkable hosts for heterologous production due to their versatile nature of expressing various secondary metabolite biosynthetic gene clusters and secretory enzymes. However, there are several issues that limit their use, including low yield, difficulty in genetic manipulation, and their complex cellular features. In this review, we summarize rational engineering approaches to optimizing the heterologous production of secondary metabolites and recombinant proteins in <i>Streptomyces</i> species in terms of genetic tool development and chassis construction. Further perspectives on the development of optimal <i>Streptomyces</i> chassis by the design-build-test-learn cycle in systems are suggested, which may increase the availability of secondary metabolites and recombinant proteins.
Rapid recovery from transient faults in the fault-tolerant processor with fault-tolerant shared memory (2002)

The Draper fault-tolerant processor with fault-tolerant shared memory (FTP/FTSM), which is designed to allow application tasks to continue execution during the memory alignment process, is described. Processor performance is not affected by memory alignment. In addition, the FTP/FTSM incorporates a hardware scrubber device to perform the memory alignment quickly during unused memory access cycles. The FTP/FTSM architecture is described, followed by an estimate of the time required for channel reintegration.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Multi-institutional noninvasive in vivo characterization of IDH, 1p/19q, and EGFRvIII in glioma using neuro-Cancer Imaging Phenomics Toolkit (neuro-CaPTk) (2020)

Using machine learning algorithms, high accuracy was achieved in the prediction of <i>IDH</i>, 1p/19q, and EGFRvIII mutation. Neuro-CaPTk encompasses all the pipelines required to replicate these analyses in multi-institutional settings and could also be used for other radio(geno)mic analyses.
EPR Investigations to Study the Impact of Mito-Metformin on the Mitochondrial Function of Prostate Cancer Cells (2022)

MM10 altered the OCR in prostate cancer cells. The effect of MM10 on the superoxide level was dependent on the antioxidant capacity of cell line. In vivo, MM10 alleviated tumor hypoxia, yet without consequence in terms of response to irradiation.
A Latent Variable Approach for Meta-Analysis of Gene Expression Data from Multiple Microarray Experiments (2007)

The statistical methods described in the paper are available as an R package, metaArray 1.8.1, which is at Bioconductor, whose URL is http://www.bioconductor.org/.
Inducible T Cell Tyrosine Kinase Regulates Actin-Dependent Cytoskeletal Events Induced by the T Cell Antigen Receptor (2003)

The tec family kinase, inducible T cell tyrosine kinase (Itk), is critical for both development and activation of T lymphocytes. We have found that Itk regulates TCR/CD3-induced actin-dependent cytoskeletal events. Expression of Src homology (SH) 2 domain mutant Itk transgenes into Jurkat T cells inhibits these events. Furthermore, Itk(-/-) murine T cells display significant defects in TCR/CD3-induced actin polymerization. In addition, Jurkat cells deficient in linker for activation of T cells expression, an adaptor critical for Itk activation, display impaired cytoskeletal events and expression of SH3 mutant Itk transgenes reconstitutes this impairment. Interestingly, expression of an Itk kinase-dead mutant transgene into Jurkat cells has no effect on cytoskeletal events. Collectively, these data suggest that Itk regulates TCR/CD3-induced actin-dependent cytoskeletal events, possibly in a kinase-independent fashion.
Prognostic Value of flow cytometric DNA content analysis in granulosa cell tumor of the ovary (1990)

The nuclear DNA content and S-phase fraction of 23 ovarian granulosa cell tumors were measured from paraffin-embedded tissue with flow cytometry. Crude survival of the patients with a euploid tumor (17 diploid, one tetraploid) was more favorable than that of the patients with an aneuploid tumor (n = 5, P = 0.02). The percentage of S-phase cells was a good predictor of survival. If more than 6% S-phase cells were present in the DNA histogram, both crude survival (P = 0.0001) and survival corrected for intercurrent deaths (P = 0.0001) were clearly inferior as compared with tumors with less than 6% S-phase cells. The results indicate that DNA flow cytometric study may provide a rapid and valuable method to predict the biological behavior of granulosa cell tumors of the ovary.