gebhart/patrepeval huggingface dataset:
Seamless Multicast Interoperability between EVPN and MVPN PEs (2019)

Ethernet Virtual Private Network (EVPN) solution is becoming pervasive
for Network Virtualization Overlay (NVO) services in data center (DC)
networks and as the next generation VPN services in service provider
(SP) networks. As service providers transform their networks in their
COs toward next generation data center with Software Defined
Networking (SDN) based fabric and Network Function Virtualization
(NFV), they want to be able to maintain their offered services
including Multicast VPN (MVPN) service between their existing network
and their new Service Provider Data Center (SPDC) network seamlessly
without the use of gateway devices. They want to have such seamless
interoperability between their new SPDCs and their existing networks
for a) reducing cost, b) having optimum forwarding, and c) reducing
provisioning. This document describes a unified solution based on RFCs
6513 & 6514 for seamless interoperability of Multicast VPN between
EVPN and MVPN PEs. Furthermore, it describes how the proposed solution
can be used as a routed multicast solution in data centers with only
EVPN PEs.
Ancestral causal learning in high dimensions with a human genome-wide\n application (2019)

We consider learning ancestral causal relationships in high dimensions. Our\napproach is driven by a supervised learning perspective, with discrete\nindicators of causal relationships treated as labels to be learned from\navailable data. We focus on the setting in which some causal (ancestral)\nrelationships are known (via background knowledge or experimental data) and put\nforward a general approach that scales to large problems. This is motivated by\nproblems in human biology which are characterized by high dimensionality and\npotentially many latent variables. We present a case study involving\ninterventional data from human cells with total dimension $p \\! \\sim \\!\n19{,}000$. Performance is assessed empirically by testing model output against\npreviously unseen interventional data. The proposed approach is highly\neffective and demonstrably scalable to the human genome-wide setting. We\nconsider sensitivity to background knowledge and find that results are robust\nto nontrivial perturbations of the input information. We consider also the\ncase, relevant to some applications, where the only prior information available\nconcerns a small number of known ancestral relationships.\n
The MIRAS “all-licef” calibration mode (2016)

Since each of the individual elements of the MIRAS array is a total power radiometer, the zero-spacing visibility can be obtained by the average of all the corresponding antenna temperatures. The main advantage of this option with respect to using the NIR measurements is that amplitude calibration is more consistent between zero-spacing visibility and the rest. On the other hand, total power radiometers are not usually as stable as noise injection radiometers, so a small loose of stability could be expected. Preliminary results show, however, similar performance.
Light‐responsive current generation by phototrophically enriched anode biofilms dominated by green sulfur bacteria (2012)

The objective of this study was to employ microbial electrochemical cells (MXCs) to selectively enrich and examine anoxygenic photosynthetic bacteria for potential anaerobic respiration capabilities using electrodes. In the process, we designed a novel enrichment strategy that manipulated the poised anode potential, light, nitrogen availability, and media supply to promote growth of phototrophic bacteria while minimizing co-enrichment of non-phototrophic anode-respiring bacteria (ARB). This approach resulted in light-responsive electricity generation from fresh- and saltwater inocula. Under anoxic conditions, current showed a negative light response, suggesting that the enriched phototrophic consortia shifted between phototrophic and anaerobic respiratory metabolism. Molecular, physical, and electrochemical analyses elucidated that anode biofilms were dominated by green sulfur bacteria, and biofilms exhibited anode respiration kinetics indicative of non-mediated electron transfer, but kinetic parameters differed from values previously reported for non-phototrophic ARB. These results invite the utilization of MXCs as microbiological tools for exploring anaerobic respiratory capabilities among anoxygenic photosynthetic bacteria.
Nanoconfined Proteins and Enzymes: Sol—Gel-Based Biomolecular Materials (1996)

Nanostructured materials obtained by sol-gel encapsulation of biomolecules are a novel class of biomaterials. The biological macromolecules, confined within the nanometer-size pores of the matrix, show both similarities to and differences from solution characteristics. The effects of nanoconfinement on the structural and reactivity patterns of the proteins and enzymes are discussed. The applications of these nanostructured biomaterials in the area of molecular biorecognition, detection, and biosensing are also presented.
Effect of Electric Field on Coulomb‐Stabilized Excitons in Host/Guest Systems for Deep‐Blue Electrophosphorescence (2009)

Abstract Here, a study of the electric field induced quenching on the phosphorescence intensity of a deep‐blue triplet emitter dispersed in different host materials is presented. The hosts are characterized by a higher triplet excitonic level with respect to the emitter, ensuring efficient energy transfer and exciton confinement, whereas they differ in the highest occupied molecular orbital (HOMO) alignment, forming type I and type II host/guest heterostructures. While the type I structure shows negligible electric field induced quenching, a quenching up to 25% for the type II at a field of 2 MV/cm is reported. A similar quenching behaviour is also reported for thin films of the pure emitter, revealing an important luminescence loss mechanism for aggregated emitter molecules. These results are interpreted by considering Coulomb stabilized excitons in the type II heterostructure and in the pure emitter, that become very sensitive to dissociation upon application of the field. These results clarify the role of external electric field quenching on the phosphorescence of triplet emitters and provide useful insights for the design of deep‐blue electrophosphorescent devices with a reduced efficiency roll‐off.
Supplementary Data from Epigenetic Silencing Affects l-Asparaginase Sensitivity and Predicts Outcome in T-ALL (2023)

&lt;p&gt;supplementary data Figure S1. Gene expression signatures define distinct molecular groups of T-ALL. Figure S2. Global flow chart of the patients Figure S3. Comparison of outcomes between LALA94 patients with central lab onco-genetic study performed (dotted line) and patients without (full line). Figure S4. Epigenetic histone marks. Figure S5. Kaplan-Meier graph for OS is shown for TAL1+ patients treated on LALA-94 vs. GRAALL-2003/2005 trials. Figure S6. TAL1 expression normalised to GAPDH by RTQ-PCR in 8 PDX treated with L-asparaginase (Rf. Figure 4H). Figure S7. (A) Correlation analysis between ASNS expression and ASNS promoter methylation ratio. (B) ASNS transcriptional expression normalized to GAPDH in T-ALL, in normal Bone Marrow (BM) (100%, 50%, 10% and 1%) and in normal Peripheral Blood Cells (PBL) (100%, 50%, 10% and 1. (C) comparison of ASNS transcriptional expression in non-sorted diagnostic sample, blast and non-blast sorted cells in two patients with a hypermethylated ASNS promoter (UPNT-573 and UPNT-498) and high ASNS expression (T3 tertile) (left) and, in primary samples and PDX (Primary Derived Xenograft) using a human specific Taqman system for two hypermethylated cases (UPNT-485 and UPNT-419) and two hypomethylated cases (UPNT-615 and UPNT-241) (right). (D) Correlation analysis between ASNS expression and ASNS promoter methylation ratio in purified blasts cells (PDX n=8 )and sorted primary samples (n=3). (E) Correlation analysis between ASNS expression (RNA-seq) and ASNS promoter methylation ratio in a series of 13 T-ALL cell lines (LOUCY, DND41, RPMI8402, HPB-ALL, ALL-SIL, TALL1, MOLT3, PEER, SUPT1, PF382, MOLT3, MOLT16, JURKAT). Table S1. Clinico-biological characteristics of patients included in the LALA94 trial according to their inclusion in the present study. Table S2. GRAALL03, 05 and LALA94 trials overview and drug administration schedule. Table S3. SiRNA sequences Table S4. Probes sequences for ASNS MS-MLPA analysis Table S5. DNA Global Methylation study Table S6. Characteristics of TLX1+, TLX3+ and TLX neg patients Table S7. Clinico-biological characteristics of T1 (lower ASNS methylation tertile) and T2+T3 (higher methylation tertiles) adult T-ALL. Table S8. Univariate and multivariate analysis for EFS and OS&lt;/p&gt;
Convergence of YAP/TAZ, TEAD and TP63 activity is associated with bronchial premalignant severity and progression (2023)

Our study identifies important gene regulatory functions for YAP/TAZ-TEAD-TP63 in the early stages of lung cancer development, which notably includes immune-suppressive roles, and suggest that an assessment of the activity of this transcriptional complex may offer a means to identify immune evasive bronchial PMLs and serve as a potential therapeutic target.
The Effects of Manufacturing Tolerances on Gas Turbine Cooling (2008)

This study presents a summary of the effects of manufacturing methods and processing steps upon the resulting thermal boundary conditions for typical highly cooled turbine airfoils. Specific emphasis is placed on the conservatism that must be “designed into” the component for survival due to realistic manufacturing tolerances. Using the features of a typical blade design, the main geometric factors that can influence the blade heat transfer capability through manufacturing variability are enumerated. The tolerances on those geometric factors are provided and the approximate quantitative impact on thermal boundary conditions is summarized. A simple example of airfoil cooling for a representative wall section is used to tabulate the variations with the resulting changes in the most affected thermal boundary conditions. Each of the main geometric factors is then evaluated in terms of its possible effect on maximum metal temperature. Paretos of the effects of manufacturing factors exhibit which factors are key and where tighter tolerances may help. Monte Carlo analysis results show the probability distributions associated with overall cooling changes tied to the tolerances.
A Mode Decoupling Method for Circular Patch Antennas (2021)

Abstract In this contribution, we investigate the effect of mode decoupling for dual-feed circular patch antennas. We consider an antenna comprising a circular disc patch placed inside an annular-ring patch. Both patches are resonant radiators, which can be fed by two different vertical posts. Due to the field interaction of the patches, the feeds experience parasitic cross-talk limiting the receive diversity performance of the system. Here, we demonstrate the possibility to suppress the cross-talk at the operational frequency by including a capacitive decoupling element into the circular patch. The physical mechanism of the method consists in the excitation of two different eigenmodes (TM01 and TM11) in a certain combination canceling the mutual coupling. The presented decoupling method can be used for patches operating either at the same frequency or at two different frequencies. In the proposed dual-feed antenna it is possible to achieve an isolation level of better than -45 dB. In contrast to the method of decoupling and matching network used for the same type of antennas, one does not need couplers to feed the patches, which reduces losses.
The lipo-oligosaccharides of <I>Haemophilus influenzae</I>: an interesting array of characters (2003)

The composition of the lipo-oligosaccharide (LOS) of Haemophilus influenzae is highly variable, especially in the oligosaccharide region. Many of the biosynthetic and transferase genes involved in LOS biosynthesis vary in seemingly random fashion by means of polymerase stuttering within redundant sequences in the 5'-portion of the genes. This results in a heterogeneous population of individual bacteria expressing literally thousands of LOS glycoforms. The simultaneous variation in the expression and structural context of a large number of individual carbohydrate and lipid structures within the LOS yields a diverse array of LOS glycoforms. The expression of glycoforms that mimic host structures may allow the organism to evade innate defenses and to manipulate host cell biology. We review how this randomly generated bacterial combinatorial chemistry results in the production of a large number of carbohydrate structures, in essentially any conceivable structural context, some of which allow the organism to utilize host cell receptors. By generating a diverse population of bacteria expressing different LOS glycoforms, discrete H. influenzae subpopulations may be adapted for survival of different environmental stresses within the airways. Thus, H. influenzae utilizes a simple and efficient "Monte Carlo" strategy for achieving maximal variation in cell surface structures, which allow the organism to adapt efficiently to environmental stresses with a small genome.
Enhancement of bone regeneration and graft material resorption using surface-modified bioactive glass in cortical and human maxillary cystic bone defects. (2004)

Results of both the clinical and animal studies suggest that the use of surface-modified bioactive glass covered with a hydroxycarbonate apatite layer has the potential to accelerate bone formation and graft material resorption better than unmodified bioactive glass.
ChemInform Abstract: Synthetic Use of the Organochromium(III) Intermediate in the Reductive Cyclization of δ6,7‐Unsaturated α‐Bromo Esters with Chromium(II) Acetate. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A Technique to Flush Out Stone Fragments Through a Ureteral Access Sheath During Retrograde Intrarenal Surgery (2019)

<b><i>Background:</i></b> Retrograde intrarenal surgery (RIRS) has become the preferred treatment option for selected renal stones <20 mm. However, laser fragmentation of stones often results in residual small fragments that may prompt subsequent stone events. We describe a simple technique to facilitate removal of these fragments. <b><i>Case Presentation:</i></b> A 68-year-old woman underwent elective RIRS for a 13 mm right renal pelvic stone. After laser fragmentation of the stone there were numerous <2 mm fragments too small to allow removal by a standard retrieval basket (i.e., NCircle<sup>®</sup> and NCompass<sup>®</sup> Nitinol Stone Extractors, Cook Medical, Bloomington, IN). A smaller ureteral access sheath (UAS) was advanced into the kidney within the preexisting larger UAS and, using a connecting piece from a Foley catheter, stone fragments were suctioned out through the smaller sheath. Stone-free status was corroborated endoscopically and with postoperative CT. <b><i>Conclusion:</i></b> Stone fragments were flushed from the kidney using a simple irrigation technique through a coaxial UAS.
SIGNAL TRANSDUCTION THERAPY OF TUMORS WITH MULTIPLE TARGET KINASE INHIBITORS (2008)

A significant increase in FS was observed in children with Omicron SARS-CoV-2 infection. A higher body temperature, a history of FS, a higher procalcitonin level, and a high neutrophil count were all associated with an increased risk of FS in children with COVID-19. The risk of developing FS was lower in children with COVID-19 and low eosinophil counts and hemoglobin levels than in those without.
Position Control Based Object Grasping Characteristics of a Multifingerd hand (2003)

In this paper we present the grasping control system based on the position control. The slide mode control, which excels in robustness, is used for the position controller. Due to grasping is made by the position control, it is not necessary that the change of the control rule accompanying approach/grasp phase. Therefore the control system is stable. Grasping objects may slip from fingertips, when the mass of grasping objects and the attitude of the manipulators, which attached hands on, changes. To avoid the slide between fingers and objects, the friction coefficient is identified in real time. And we consider that objects begin to slip when the value exceeds the maximum coefficient of friction. To regard the coefficient as a threshold, the grasping force is made to increase by making the compliance of joints increase. The proposed control system is actually applied to a multifingerd hand, and the usefulness was verified.
Night vision in Thales Angenieux: custom solutions for handheld devices (2004)

Thales Angenieux has been developing for almost two decades, compact and flexible light intensifier goggles that are in service through numerous countries. More recently, a new product line, called Elvir, has been launched which is based upon uncooled sensitive arrays: as a consequence, Thales Angenieux has now at command a full set of night vision equipment's, answering most of the operational purposes. A 'blocks' policy has been used to cut the non-recurring expenses: the thermal camera re-uses some upgraded sub-assemblies of the previous IL goggles. This paper reviews the main trades off, showing how we relied on earlier and successful designs to meet the best compromises between performances, costs and compactness. Some issues, such as the front infrared optics set up, will be emphasized later on. The choices that have ruled the visualization unit design will be outlined. Future prospects backing the latest technologies breakthroughs wil be sketched out: topics such as new infrared materials and hybrid lenses made of subwavelength features are addressed.
Analysis of the Anatomical Characteristics of the Pelvis in Koreans to Aid in Development of a NOTES Platform (2012)

Transanal endoscopic microsurgery (TEM) is a minimally invasive technique affording full-thickness resection of rectal tumors and can also be used as a platform for transrectal access to the peritoneal cavity for NOTES (natural orifice transluminal endoscopic surgery) procedures. The authors investigated the anatomical characteristics of the pelvis in Koreans to develop an ergonomically designed NOTES platform. A total of 256 patients (156 men and 100 women) who underwent pelvic magnetic resonance imaging for evaluating rectal neoplasms were enrolled for analysis. The authors retrospectively reviewed and calculated anatomical lengths and angles on pelvic magnetic resonance images and analyzed differences in pelvic anatomy in terms of patient gender, age, and body mass index. Various angulations were noted from the anal canal to the sacral promontory, attributable to the shape of the sacral bone. Minimal difference in pelvic anatomy was evident between men and women. In conclusions, the authors expect that their data will be useful in the development of ergonomic TEM-NOTES platforms.
Global information management via local autonomous agents (1997)

In this paper we describe how a set of autonomous computational agents can cooperate in providing coherent management of information in environments where there are many diverse information resources. The agents use models of themselves and of the resources that are local to them. Resource models may be the schemas of databases, frame systems of knowledge bases, or process models of business operations. Models enable the agents and resources to use the appropriate semantics when they interoperate. This is accomplished by specifying the semantics in terms of a common ontology. We discuss the contents of the models, where they come from, and how the agents acquire them. We then describe a set of agents for telecommunication service provisioning and show how the agents use such models to cooperate. Their interactions produce an implementation of relaxed transaction processing. 1
A Temperature-Hardened Sensor Interface with a 12-Bit Digital Output Using a Novel Pulse Width Modulation Technique (2018)

A fully integrated sensor interface for a wide operational temperature range is presented. It translates the sensor signal into a pulse width modulated (PWM) signal that is then converted into a 12-bit digital output. The sensor interface is based on a pair of injection locked oscillators used to implement a differential time-domain architecture with low sensitivity to temperature variations. A prototype has been fabricated using a 180 nm partially depleted silicon-on-insulator (SOI) technology. Experimental results demonstrate a thermal stability as low as 65 ppm/°C over a large temperature range from -20 °C up to 220 °C.
Efficient Molecular Genetic Diagnosis of Enlarged Vestibular Aqueducts in East Asians (2009)

Our study further defines the spectrum of SLC26A4 mutations among East Asians and demonstrates a rapid and efficient protocol for their detection.
Keyframe-based modeling and tracking of multiple 3D objects (2010)

We propose a real-time solution for modeling and tracking multiple 3D objects in unknown environments. Our contribution is two-fold: First, we show how to scale with the number of objects. This is done by combining recent techniques for image retrieval and online Structure from Motion, which can be run in parallel. As a result, tracking 40 objects in 3D can be done within 6 to 25 milliseconds per frame, even under difficult conditions for tracking. Second, we propose a method to let the user add new objects very quickly. The user simply has to select in an image a 2D region lying on the object. A 3D primitive is then fitted to the features within this region, and adjusted to create the object 3D model. In practice, this procedure takes less than a minute.
Type 2 innate immune responses and the natural helper cell (2011)

The T helper type 2 (Th2) immune response, characterized by the production of interleukin-4 (IL-4), IL-5 and IL-13, is a critical immune response against helminths invading cutaneous or mucosal sites. It also plays a critical role in the pathophysiology of allergic diseases such as asthma and allergic diarrhoea. The Th2 cytokines are induced soon after helminth infection, even before a pathogen-specific adaptive immune response is established. Recent studies have shed light on such innate Th2 cytokine production by formerly uncharacterized innate immune cells such as natural helper cells capable of producing Th2 cytokines in response to IL-25 and IL-33 independently of adaptive immune responses. These cells produce large amounts of Th2 cytokines, most notably IL-5 and IL-13, leading to eosinophilia and goblet cell hyperplasia. We discuss here the mechanisms of innate production of Th2 cytokines in host immune responses against helminth infection as well as allergic immune responses and the similarities and differences between recently identified Th2-cytokine producing cells.
Adsorption Equilibria of Chloropentafluoroethane and Pentafluoroethane on Activated Carbon Pellet (1998)

Equilibrium studies on the adsorption of chloropentafluoroethane (R-115, CF3CF2Cl) and pentafluoroethane (CF3CF2H, R-125) on an activated carbon pellet were made between 298.2 K and 373.6 K. Equilibrium parameters based on the Langmuir−Freundlich equation are derived. The Langmuir−Freundlich isotherms for R-115 and R-125 fit the experimental results within 2%. The isosteric enthalpies of adsorption of R-115 and R-125 were estimated.