gebhart/patrepeval huggingface dataset:
Facile Strategy for Fabricating an Organosilica-Modified Fe3O4 (OS/Fe3O4) Hetero-nanocore and OS/Fe3O4@SiO2 Core–Shell Structure for Wastewater Treatment with Promising Recyclable Efficiency (2023)

The development of a sustainable process for heavy metal ion remediation has become a point of interest in various fields of research, including wastewater treatment, industrial development, and health and environmental safety. In the present study, a promising sustainable adsorbent was fabricated through continuous controlled adsorption/desorption processes for heavy metal uptake. The fabrication strategy is based on a simple modification of Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles with organosilica in a one-pot solvothermal process, carried out in order to insert the organosilica moieties into the Fe<sub>3</sub>O<sub>4</sub> nanocore during their formation. The developed organosilica-modified Fe<sub>3</sub>O<sub>4</sub> hetero-nanocores had hydrophilic citrate moieties, together with hydrophobic organosilica ones, on their surfaces, which facilitated the further surface coating procedures. To prevent the formed nanoparticles from leaching into the acidic medium, a dense silica layer was coated on the fabricated organosilica/Fe<sub>3</sub>O<sub>4</sub> (OS/Fe<sub>3</sub>O<sub>4</sub>). In addition, the prepared OS/Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> was utilized for the adsorption of cobalt(II), lead(II), and manganese(II) from the solutions. The data for the adsorption processes of cobalt(II), lead(II), and manganese(II) on OS/(Fe<sub>3</sub>O<sub>4</sub>)@SiO<sub>2</sub> were found to follow the pseudo-second-order kinetic model, indicating the fast uptake of heavy metals. The Freundlich isotherm was found to be more suitable for describing the uptake of heavy metals by OS/Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticles. The negative values of the Δ<i>G</i>° showed a spontaneous adsorption process of a physical nature. The super-regeneration and recycling capacities of the OS/Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> were achieved, comparing the results to those of previous adsorbents, with a recyclable efficiency of 91% up to the seventh cycle, which is promising for environmental sustainability.
Online Estimation of Reverberation Parameters For Late Residual Echo Suppression (2019)

In hands-free telephony and other distant-talk applications, often a short AEC filter is used to achieve fast convergence at low computational cost. As a result, a significant amount of late residual echo (LRE) may remain, especially in highly reverberant environments. This LRE can be suppressed using a postfilter in the subband domain, which requires an estimate of the power spectral density (PSD) of the LRE. To estimate the LRE PSD, an exponentially decaying model with frequency-dependent reverberation scaling and decay parameters has frequently been assumed. State-of-the-art methods estimate both reverberation parameters independently of each other, either in offline or in online mode. In this article, we propose two signal-based methods (i.e. output error and equation error) to jointly estimate both reverberation parameters in online mode. The estimated parameters are then used to generate an estimate for the LRE PSD, which is fed into a postfilter for the purpose of late residual echo suppression. We derive several gradient-descent-based algorithms to simultaneously update both reverberation parameters, minimizing either the mean squared error or the mean squared log error cost function. The proposed methods are compared with state-of-the-art methods in terms of the accuracy of the estimated reverberation parameters and the corresponding LRE PSD estimate. Extensive simulation results using both artificial as well as measured room impulse responses show that the proposed output error method with mean squared log error minimization outperforms state-of-the-art methods in all considered scenarios.
A scheduling and binding heuristic for high-level synthesis of fault-tolerant FPGA applications (2015)

Space computing systems commonly use field-programmable gate arrays to provide fault tolerance by applying triple modular redundancy (TMR) to existing register-transfer-level (RTL) code. Although effective, this approach has a 3× area overhead that can be prohibitive for many designs that often allocate resources before considering effects of redundancy. Although a designer could modify existing RTL code to reduce resource usage, such a process is time consuming and error prone. Integrating redundancy into high-level synthesis is a more attractive approach that enables synthesis to rapidly explore different tradeoffs at no cost to the designer. In this paper, we introduce a scheduling and binding heuristic for high-level synthesis that explores tradeoffs between resource usage, latency, and the amount of redundancy. In many cases, an application will not require 100% error correction, which enables significant flexibility for scheduling and binding to reduce resources. Even for applications that require 100% error correction, our heuristic is able to explore solutions that sacrifice latency for reduced resources, and typically save up to 47% when relaxing the latency up to 2×. When the error constraint is reduced to 70%, our heuristic achieves typical resource savings ranging from 18% to 49% when relaxing the latency up to 2×, with a maximum of 77%. Even when comparing with optimized RTL designs, our heuristic uses up to 61% fewer resources than TMR.
Growth kinetics of intermetallic compound layers at the interface during laser-assisted bonding depending on surface finish (2020)

Mass reflow (MR) has been widely used in the interconnecting process of electronic packaging. However, use of conventional MR shows a limitation in the miniaturization trend of electronic devices because of thermal damage to heat- sensitive polymer components from the high process temperature and long bonding time. Furthermore, MR cannot avoid warpage issues because it cannot provide thermal selectivity to the bonding area. These representative problems of MR indicate the need for an advanced bonding process with selectivity and mass product possibility. To meet the requirements of electronic packaging, advanced bonding processes were needed. Laser-assisted bonding (LAB) has been spotlighted as a next-generation interconnection technology to overcome the problems of MR. LAB has extremely fast ramping up speed with accurately controlled wavelength and excellent thermal selectivity. The LAB process could be applied in bonding of flexible, foldable, and even stretchable applications involving a polymer component with a low glass transition temperature. Furthermore, the short process time of LAB could provide not only enhanced productivity, but improvement in mechanical properties as a result of finer grain size and reduction in intermetallic compound (IMC) formation.SAC305 solder paste was printed on two kinds (OSP and ENEPIG) of surface-finished Cu electrode, and MR and LAB processes were performed to create solder joints. The mechanical reliability of solder joint was evaluated with shear test according to the JEDEC standard. Formation and growth of an IMC layer at the interface between SAC solder and Cu after soldering were identified with FESEM. A high- temperature storage test was performed to evaluate the longterm reliability of LAB compared to that of MR. Voids in solder joints were identified by x-ray scanner to compare the soldering processes and surface finish depending on aging time. Smaller IMC layer between solder joint and electrode thickness and fewer voids in solder joints were produced with LAB compared to MR.
Figure S4 from Nanoconjugation of PSMA-Targeting Ligands Enhances Perinuclear Localization and Improves Efficacy of Delivered Alpha-Particle Emitters against Tumor Endothelial Analogues (2023)

&lt;p&gt;Effect of the presence of CCM on PSMA expression over time.&lt;/p&gt;
Dynamics of anti-MSP3 and Pfs230 antibody responses and multiplicity of infection in asymptomatic children from southern Ghana (2018)

Microscopy can more accurately predict changes in parasite prevalence in high transmission settings than low transmission settings. In high transmission settings, P. falciparum parasite prevalence can predict antibody seroprevalence to MSP3, whilst in low transmission settings, seroprevalence against Pfs230 may be a useful predictor of parasite prevalence.
Device Delay in GaN Transistors Under High Drain Bias Conditions (2013)

This letter studies the drain delay caused by the extension of the effective gate length in high-frequency GaN high electron mobility transistors. It is shown that the drain delay is mainly reflected in the gate-to-source capacitance ( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">C</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">gs</sub> ) of the device. The ratio of <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">C</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">gs</sub> and transconductance ( <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">gm</i> ) is then used to accurately extract the drain delay and the result is compared with other extraction methods reported in the literature. Finally, we will use this new extraction technique to explain why short channel GaN devices show higher drain delay than longer channel transistors.
On-line grid impedance estimation based on harmonic injection for grid-connected PV inverter (2007)

The paper presents an on-line software method for impedance estimation of the energized impedances such as power system grid. The proposed method is based on producing a perturbation on the output of the power converter that is in the form of periodical injection of one or two voltage harmonic signals. The single harmonic injection uses a 600 Hz signal and the double harmonic injection uses a 400 Hz and 600 Hz signals, respectively. During the perturbation, the current response(s) at the same frequency as the injected signal(s) is/are measured. The value of the grid impedance is estimated using two different signal processing algorithms. The DFT technique is used for the single harmonic injection and the statistic technique is used for the double harmonic injection. The grid impedance estimation is used for compliance with the anti-islanding requirements of the German standard (VDE0126) and for robust control of the distributed power generation systems (DPGS). Selected results are presented to confirm the performances of the proposed method.
Microspheres: Design and Manufacturing (2005)

Many new candidate therapeutic agents are extremely potent and must be dispensed in a controlled and accurate fashion, preferably at the site of action. These compoundsmay be delivered by a number of routes of administration each offering advantages and limitations based on the application.
Short Course: Embedded Power Management for IC Designers (2008)

Presents an outline and description of the above titled short course from the conference proceedings.
Geometric approximation model of inter-lidar interference (2020)

Signal interference between two light detection and ranging (lidar) scanners can occur when the transmitted laser energy from one lidar is coupled into a second lidar either by scattering or direct transmission. By ray tracing lidar transmission paths, it is shown that signal interference can be modeled with the coincidence of intersections between two lidars’ optical axes and a scattering target or medium. A geometric analysis of intersecting transmission paths is presented for circularly scanning lidars from which theoretical interference risks between two lidars may be deduced. Using the geometric rules proposed here for interference, a Monte Carlo simulation is presented that models interference risks and occurrences. This geometric approximation simplifies analysis by ignoring radiometry for scanners within proximity to one another. Simulation results are used to introduce the concept of intersection point density from which one may assess areas of greatest interference risk for two-lidar, in-plane scanning lidar configurations. It is shown from the intersection point density that the risk for signal interference between two lidars exponentially increases as targets are located closer to and between the two scanners. Simulation results are compared to previously published experimental observations of interference to demonstrate the theory’s potential for interference modeling.
A Blueprint for a Manageable and Affordable Wireless Testbed: Design, Pitfalls and Lessons Learned (2007)

In this paper, we describe the deployment efforts of our 802.11 indoor wireless testbed. We elucidate the challenges that we faced and the design decisions that we had to make, sometimes based on technical reasons, and other times due to practicalities. These design challenges involve: (a) accessibility to the software, in order to be able to modify and implement various functionalities, (b) physical extendability, in order to add hardware in the future and, (c) manageability, in order to configure and update the software easily and quickly, for all the nodes in the network. We justify the hardware and software design choices that we make in order to facilitate these requirements. For ease of maintenance and convenience, each node is diskless, and we utilize power-over-ethernet through an Ethernet connection with a central server. We ensure that the software can be easily modified; this provides for easier module implementation and parameter tuning. We explain the different ways of node deployment, decisions that we make on power settings and discuss how and why the receiver sensitivity affects deployment decisions. Finally, we present our observations based on a set of measurements to quantify the stability of the links in our testbed.
Compatibilization of Immiscible Polymer Networks Through Photopolymerization in a Lyotropic Liquid Crystal (2006)

The self-assembled, nanoscale domains of a lyotropic liquid crystal are used as a compatibilizing platform for the simultaneous polymerization of immiscible hydrophilic and hydrophobic crosslinking monomers (see figure). The influence of the liquid crystal reduces phase separation, resulting in a material with properties similar to those of a highly compatible polymer blend. The direct dependence of material properties on the composition of the crosslinking blend indicates the formation of a type of interpenetrating network.
Invasive left ventricle pressure–volume analysis: overview and practical clinical implications (2019)

Ventricular pressure-volume (PV) analysis is the reference method for the study of cardiac mechanics. Advances in calibration algorithms and measuring techniques brought new perspectives for its application in different research and clinical settings. Simultaneous PV measurement in the heart chambers offers unique insights into mechanical cardiac efficiency. Beat to beat invasive PV monitoring can be instrumental in the understanding and management of heart failure, valvular heart disease, and mechanical cardiac support. This review focuses on intra cardiac left ventricular PV analysis principles, interpretation of signals, and potential clinical applications.
Observation of the decay Bs0→ϕπ+π− and evidence for B0→ϕπ+π− (2017)

The first observation of the rare decay ${B}_{s}^{0}\ensuremath{\rightarrow}\ensuremath{\phi}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ and evidence for ${B}^{0}\ensuremath{\rightarrow}\ensuremath{\phi}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ are reported, using $pp$ collision data recorded by the LHCb detector at center-of-mass energies $\sqrt{s}=7$ and 8 TeV, corresponding to an integrated luminosity of $3\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$. The branching fractions in the ${\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ invariant mass range $400&lt;m({\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}})&lt;1600\text{ }\text{ }\mathrm{MeV}/{c}^{2}$ are $[3.48\ifmmode\pm\else\textpm\fi{}0.23\ifmmode\pm\else\textpm\fi{}0.17\ifmmode\pm\else\textpm\fi{}0.35]\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}6}$ and $[1.82\ifmmode\pm\else\textpm\fi{}0.25\ifmmode\pm\else\textpm\fi{}0.41\ifmmode\pm\else\textpm\fi{}0.14]\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}7}$ for ${B}_{s}^{0}\ensuremath{\rightarrow}\ensuremath{\phi}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ and ${B}^{0}\ensuremath{\rightarrow}\ensuremath{\phi}{\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ respectively, where the uncertainties are statistical, systematic and from the normalization mode ${B}_{s}^{0}\ensuremath{\rightarrow}\ensuremath{\phi}\ensuremath{\phi}$. A combined analysis of the ${\ensuremath{\pi}}^{+}{\ensuremath{\pi}}^{\ensuremath{-}}$ mass spectrum and the decay angles of the final-state particles identifies the exclusive decays ${B}_{s}^{0}\ensuremath{\rightarrow}\ensuremath{\phi}{f}_{0}(980)$, ${B}_{s}^{0}\ensuremath{\rightarrow}\ensuremath{\phi}{f}_{2}(1270)$, and ${B}_{s}^{0}\ensuremath{\rightarrow}\ensuremath{\phi}{\ensuremath{\rho}}^{0}$ with branching fractions of $[1.12\ifmmode\pm\else\textpm\fi{}0.1{6}_{\ensuremath{-}0.08}^{+0.09}\ifmmode\pm\else\textpm\fi{}0.11]\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}6}$, $[0.61\ifmmode\pm\else\textpm\fi{}0.1{3}_{\ensuremath{-}0.05}^{+0.12}\ifmmode\pm\else\textpm\fi{}0.06]\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}6}$ and $[2.7\ifmmode\pm\else\textpm\fi{}0.7\ifmmode\pm\else\textpm\fi{}0.2\ifmmode\pm\else\textpm\fi{}0.2]\ifmmode\times\else\texttimes\fi{}{10}^{\ensuremath{-}7}$, respectively.
Supplementary File 1 from Tasquinimod Is an Allosteric Modulator of HDAC4 Survival Signaling within the Compromised Cancer Microenvironment (2023)

&lt;p&gt;PDF fiel - 55K, Provides source for all reagents used in this study&lt;/p&gt;
Global transcriptional profiling of Burkholderia pseudomallei under salt stress reveals differential effects on the Bsa type III secretion system (2010)

B. pseudomallei responds to salt stress by modulating the transcription of a relatively small set of genes, among which is the bsa locus associated with invasion and virulence. Expression and secretion of Bsa-secreted proteins was elevated in the presence of exogenous salt and the invasion efficiency was enhanced. Our data indicate that salinity has the potential to influence the virulence of B. pseudomallei.
Anti-PSMA/CD3 Bispecific Antibody Delivery and Antitumor Activity Using a Polymeric Depot Formulation (2018)

Small therapeutic proteins represent a promising novel approach to treat cancer. Nevertheless, their clinical application is often adversely impacted by their short plasma half-life. Controlled long-term delivery of small biologicals has become a challenge because of their hydrophilic properties and in some cases their limited stability. Here, an <i>in situ</i> forming depot-injectable polymeric system was used to deliver BiJ591, a bispecific T-cell engager (BiTE) targeting both prostate-specific membrane antigen (PSMA) and the CD3 T-cell receptor in prostate cancer. BiJ591 induced T-cell activation, prostate cancer-directed cell lysis, and tumor growth inhibition. The use of diblock (DB) and triblock (TB) biodegradable polyethylene glycol-poly(lactic acid; PEG-PLA) copolymers solubilized in tripropionin, a small-chain triglyceride, allowed maintenance of BiJ591 stability and functionality in the formed depot and controlled its release. In mice, after a single subcutaneous injection, one of the polymeric candidates, TB1/DB4, provided the most sustained release of BiJ591 for up to 21 days. Moreover, the use of BiJ591-TB1/DB4 formulation in prostate cancer xenograft models showed significant therapeutic activity in both low and high PSMA-expressing tumors, whereas daily intravenous administration of BiJ591 was less efficient. Collectively, these data provide new insights into the development of controlled delivery of small therapeutic proteins in cancer. <i>Mol Cancer Ther; 17(9); 1927-40. ©2018 AACR</i>.
Design and analysis of a photocatalytic air purification system for VOCs removal (1995)

Design and analysis of a dual photo-/thermo-catalytic air purification system for removing nitroglycerine and VOCs is given. We have employed an advanced computational fluid dynamics (CFD) program for the design and performance analysis of the reactors. A detailed description of the heat and mass transfer within the catalytic reactors is discussed and results compared to the experimental findings. Several reactor design concepts and the details of a large-scale (800 SCFM) air purification plant are described using Aspen Tech Chemical Process Simulator (CPS).
Plan execution in dynamic and unanticipated environments (2002)

The construction of planning and execution systems for complex real-time operational systems should be based on an understanding of what happens at the time of plan execution, because much of the information to constrain reasoning and decisions is not available prior to execution. The author discusses the results of research on the execution of procedures of a knowledge-rich domain (operation of a nuclear power plant) in a dynamic environment, and concludes that planning+execution is a viable model where planning is better viewed as a process for producing a 'road map' and that the research needs to focus more on the role of the executor as an intelligent navigator. It is also shown that an understanding of domain-specific execution behavior can lead to strategies for dealing with the incompleteness problem. The author briefly describes salient features of the DPS (dynamic procedure selection and synthesis) approach and shows how some of the aspects of incompleteness can be addressed by exploiting both the knowledge richness of a domain and architectural features of plan execution behavior.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Coronary Artery Disease in Very Young Patients: Analysis of Risk Factors and Long-Term Follow-Up (2022)

Coronary artery disease (CAD) is a common chronic condition in the elderly. However, the earlier CAD begins, the stronger its impact on lifestyle and costs of health and social care. The present study analyzes clinical and angiographic features and the outcome of very young patients undergoing coronary angiography due to suspected CAD, including a nested case-control study of ≤40-year-old patients referred for coronary angiography. Patients were divided into two groups: cases with significant angiographic stenosis, and controls with non-significant stenosis. Of the 19,321 coronary angiographies performed in our center in a period of 10 years, 504 (2.6%) were in patients ≤40 years. The most common cardiovascular risk factors for significant CAD were smoking (OR 2.96; 95% CI 1.65-5.37), dyslipidemia (OR 2.18; 95% CI 1.27-3.82), and family history of CAD (OR 1.95; 95% CI 1.05-3.75). The incidence of major adverse cardiovascular events (MACE) at follow-up was significantly higher in the cases compared to controls (HR 2.71; 95% CI 1.44-5.11). Three conventional coronary risk factors were directly related to the early signs of CAD. MACE in the long-term follow-up is associated to dyslipidaemia and hypertriglyceridemia. Focusing efforts for the adequate control of CAD in young patients is a priority given the high socio-medical cost that this disease entails to society.