gebhart/patrepeval huggingface dataset:
Fast Convergence Outer Loop Link Adaptation with Infrequent Updates in Steady State (2017)

In wireless communications, link adaptation is used to select a suitable modulation and coding scheme. The purpose of link adaptation is to adapt to varying channel and interference conditions and to aim for a specified block error rate or to maximize the throughput. In support of link adaptation, there will be estimates of signal to interference ratios, path gain or transmit powers. These estimates can contain systematic and random errors, that may affect the performance of link adaptation. To correct for such errors, there is an outer loop performing link adaptation, usually based on feedback of the bit error rate. We investigate commonly used outer loop link adaptation algorithms and propose a new scheme based on sequential hypothesis testing. The new scheme is shown to converge faster at initialization and after disturbances and to have good performance in steady state.
Evidence for one or more Raf-1 kinase kinase(s) activated by insulin and polypeptide growth factors (1991)

The protein product of the Raf-1 proto-oncogene is a protein serine/threonine kinase that is activated after stimulation of cells with insulin and other mitogens. To investigate the mechanism of this activation, we used purified Raf-1 expressed in E. coli as a substrate for a putative Raf-1 protein kinase kinase. In three different insulin-sensitive cell types, insulin activated Raf-1 kinase kinase activity in crude cytosolic cellular fractions. The insulin stimulation of this activity was evident as early as 2 min after exposure to insulin, maximal at 5-8 min, and inapparent at 15 min. Phosphoamino acid analysis of phosphorylated Raf-1 revealed that serine was the primary phosphate acceptor for the insulin-activated kinase or kinases; small amounts of phosphothreonine were also detected. The insulin effect occurred in cells depleted of protein kinase C, and in extracts depleted of endogenous Raf-1 kinase by immunodepletion; these data argue against protein kinase C or Raf-1 kinase itself being the insulin-stimulated activity. The insulin-activated kinase or kinases phosphorylated the Raf-1 protein on multiple sites in vitro, as evidenced by tryptic mapping; at least some of these appeared to overlap with sites phosphorylated in response to serum in intact cells. Several other mitogens and growth factors stimulated Raf-1 kinase kinase activity, including epidermal growth factor, platelet-derived growth factor, fibroblast growth factor, serum, and phorbol 12-myristate 13-acetate. This insulin- and mitogen-stimulated Raf-1 kinase kinase activity may play a role in mediating the phosphorylation and possibly the activation of the Raf-1 kinase by insulin and other growth factors.
Frequency and Prognosis of COVID-19 in The Course of Autologous Stem Cell Transplantation (2022)

Autologous hematopoietic stem cell transplantation (ASCT) is indicated as a consolidative treatment after induction and/or salvage therapy of various hematologic malignancies, including multiple myeloma and other plasma cell disorders, Hodgkin lymphoma, and non-Hodgkin lymphomas
Comparison of single-breath and tidal breathing exhaled nitric oxide levels in infants (2004)

The aim of this study was to compare two different methods, tidal breathing (TB) and single-breath (SB), for measuring fractional exhaled nitric oxide (FENO) in infants. FENO was measured in 71 infants with either recurrent wheeze (n=32), recurrent cough (n=16) or no symptoms (healthy, n=23) using both methods. For TB measurements five breaths were collected into a gas sampling bag (off-line reservoir sampling). The SB method was modified from the raised volume rapid thoraco-abdominal technique. Agreement between the two methods was investigated and both methods were used to compare FENO in infants with and without symptoms. Flow dependence of SB FENO was demonstrated using two expiratory flows (11 and 40 mL x s(-1)). There was a moderate correlation (r=0.60) but poor agreement between levels using the TB and SB methods. A significant difference in FENO between healthy children and children with wheeze was found using the SB but not the TB method. Due to lower expiratory flow and reduced nasal nitric oxide contamination the single-breath technique may be more sensitive than the tidal breathing method for detecting differences in exhaled nitric oxide between infants with and without respiratory symptoms.
Anti-fibrotic and Anti-tumorigenic Effects of Rhein, a Natural Anthraquinone Derivative, in Mammalian Stellate and Carcinoma Cells (2014)

Anthraquinone compounds have been recognized to possess antiinflammatory, anti-fibrotic and anti-tumour properties and thus applied in human and veterinary therapeutics as active substances of medicinal products. Amongst the anthraquinones isolated from Rheum palmatum, also known as da-huang, rhein was detected as one of the highest metabolite contents in the bloodstream of mammals. The biological activities of rhein therefore deserve detailed investigation. In this study, we aimed to delineate the mechanism of inhibitory actions of rhein on fibrotic and tumorigenic processes by means of various biochemical assays, such as immunofluorescent staining, real-time polymerase chain reaction (PCR) and western blotting analyses in rat pancreatic stellate cells (LTC-14), human pancreatic ductal adenocarcinoma cells (PANC-1) and human colon carcinoma cells (SW480 and SW620). Our results demonstrated that the application of rhein notably suppressed the mRNA and protein levels of various fibrotic and tumorigenic mediators including alpha-smooth muscle actin, type I collagen, fibronectin, N-cadherin and matrix metalloproteinases in the testing mammalian cells. The mechanism of the suppressive actions of rhein was associated with the modulation of the sonic hedgehog and serine-threonine kinase signalling pathways. In conclusion, we suggest that rhein may serve as a therapeutic or an adjuvant agent in anti-fibrotic and anti-tumorigenic approaches.
Spektrometer (2011)

Spektrometer sind Systeme, welche die spektrale Zerlegung von Licht ermöglichen. Man kann damit einerseits die von Lichtquellen ausgesendeten Anteile bei verschiedenen Wellenlängen analysieren (Emissionsspektroskopie) oder andererseits die Abschwächung des Lichts einer bekannten Quelle durch ein Medium untersuchen (Absorptionsspektroskopie).
Indium-Bridged Chelating Diamide Group IV Metal Olefin Polymerization Catalysts (2002)

The group IV metal chelating diamide complex 2 has been prepared and characterized by 1H and 13C{1H} NMR spectroscopy and single-crystal X-ray structure analysis. This complex is an active catalyst upon combining with the appropriate activator. The catalyst efficiencies, however, are considerably lower than those of Cp-based catalysts. The polydispersities of the polymers produced were found to be broader than those observed for Cp-based single-site catalytic systems.
Cutaneous cryptococcosis in solid organ transplant recipients (2010)

Clinical manifestations, treatment, and outcomes of cutaneous cryptococcosis in solid organ transplant (SOT) recipients are not fully defined. In a prospective cohort comprising 146 SOT recipients with cryptococcosis, we describe the presentation, antifungal therapy, and outcome of cutaneous cryptococcal disease. Cutaneous cryptococcosis was documented in 26/146 (17.8%) of the patients and manifested as nodular/mass (34.8%), maculopapule (30.4%), ulcer/pustule/abscess (30.4%), and cellulitis (30.4%) with 65.2% of the skin lesions occurred in the lower extremities. Localized disease developed in 30.8% (8/26), and disseminated disease in 69.2% (18/26) with involvement of the central nervous system (88.9%, 16/18), lung (33.3%, 6/18), or fungemia (55.6%, 10/18). Fluconazole (37.5%) was employed most often for localized and lipid formulations of amphotericin B (61.1%) for disseminated disease. Overall mortality at 90 days was 15.4% (4/26) with 16.7% in disseminated and 12.5% in localized disease (P = 0.78). SOT recipients who died were more likely to have renal failure (75.0% vs. 13.6%, P = 0.028), longer time to onset of disease after transplantation (87.5 vs. 22.6 months, P = 0.023), and abnormal mental status (75% vs. 13.6%, P = 0.028) than those who survived. Cutaneous cryptococcosis represents disseminated disease in most SOT recipients and preferentially involves the extremities. Outcomes with appropriate management were comparable between SOT recipients with localized and disseminated cryptococcosis.
Review: Treatment and reuse of wastewater from the textile wet‐processing industry: review of emerging technologies (1998)

New ecolabels for textile products and tighter restrictions on wastewater discharges are forcing textile wet processors to reuse process water and chemicals. This challenge has prompted intensive research in new advanced treatment technologies, some of which currently making their way to full-scale installations. These comprise polishing treatments such as filtration, chemical oxidation and specialized flocculation techniques and pre-treatment steps including anaerobic digestion, fixed-film bioreactors, Fenton's reagent oxidation, electrolysis, or foam flotation. Though several of these new technologies are promising in terms of cost and performance, they all suffer limitations which require further research and/or need broader validation. A segment of the research deals with the separate handling of specific sub-streams such as dyebath effluents to which membrane filtration is sometimes applied. The main limitation of this approach is the treatment of the concentrate stream. The spectrum of available technologies may, in the future, be further broadened to include fungi/H2O2-driven oxidation, specialized bio-sorptive processes, solvent extraction, or photocatalysis. © 1998 SCI
Automated valet parking and charging for e-mobility (2016)

Automated valet parking services provide great potential to increase the attractiveness of electric vehicles by mitigating their two main current deficiencies: reduced driving ranges and prolonged refueling times. The European research project V-Charge aims at providing this service on designated parking lots using close-to-market sensors only. For this purpose the project developed a prototype capable of performing fully automated navigation in mixed traffic on designated parking lots and GPS-denied parking garages with cameras and ultrasonic sensors only. This paper summarizes the work of the project, comprising advances in network communication and parking space scheduling, multi-camera calibration, semantic mapping concepts, visual localization and motion planning. The project pushed visual localization, environment perception and automated parking to centimetre precision. The developed infrastructure-based camera calibration and semi-supervised semantic mapping concepts greatly reduce maintenance efforts. Results are presented from extensive month-long field tests.
Resonant Microelectromechanical Receiver (2019)

This paper reports a practical demonstration of a proposed resonant microelectromechanical receiver for low power wake-up receiver (WuRx) applications. The proposed system is made of three main components: a piezoelectric based acoustic resonator, an electrostatically-driven MEMS resonant demodulator, and a CMOS baseband trigger circuit. The filtering, amplification, and demodulation of the incoming signal are performed through the piezoelectric resonator and the resonant demodulator, ensuring zero power consumption for both the radio frequency (RF) and mixing stages. The only power consumption occurs at baseband by operating the CMOS circuit in deep subthreshold. This system utilizes a lithium niobate piezoelectric resonator possessing a figure of merit of around 650 and achieving voltage gain of 28 dB. A resonant demodulator fabricated in the Epi-Seal MEMS process is utilized to attain a conversion efficiency of 13.8 nA/V <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . In the trigger circuit, an amplifier with transimpedance 200 MQ is utilized to sense the output current from the demodulator. An intermediate buffer and a multiple stage passive latch rectifier are utilized to generate the wake-up signal through a Schmitt trigger. The demonstrated system achieves -40.2 dBm sensitivity for a 44 kHz amplitude-modulated 50 MHz RF signal while consuming 38.75 nW. This architecture is a promising step toward a WuRx capable of achieving higher interference rejection, high sensitivity, and nW range power consumption at a high data rate.
Abstractions and algorithms for active multidatabases (1999)

An active database is a database that can react to its state. The ability to encode behavior within the database is a major improvement in database functionality, and allows implementing complicated applications entirely within the database. This functionality underlies many emerging application areas, such as workflow systems. 
Reactive behavior is most easily represented declaratively in the form of rules. The integration of rules and databases is not new, published research on active databases dates from the 1980s. However, previous active database systems have several common limitations. First, the rule languages are primitive, lacking language support for modularity and other features. Second, the rule processing engine is custom developed and not as efficient as the best engines from the expert system community. Finally, they are strictly homogeneous, tied directly to a single database. Before active databases will gain widespread use, these issues must be addressed. 
This dissertation concerns the VenusDB active multidatabase, with specific emphasis on three features. The first is a modular rule language with explicit constructs for active databases. This language is specifically designed to support complex rule programs executing over elements in databases. The second is an algorithm for efficiently evaluating trigger filter expressions. This technique generates decision trees that determine what trigger expressions a database element satisfies. The technique is general, and can be employed outside of VenusDB. The third is its generalized interface to databases, termed the Abstract Machine Interface (AM). The AM presents a high level interface between the rule and database components. By virtue of the AMI, active rule engines may be built that exploit challenging optimizations without altering the structure of the underlying DBMS. The abstraction is so effective, multiple databases can be integrated into a single active database program.
Supplementary Figure 1. Hierarchical clustering of response to single agent treatments. from An Unbiased Oncology Compound Screen to Identify Novel Combination Strategies (2023)

&lt;p&gt;Hierarchical clustering was performed on the response data across the cell line panel to the single agent treatments. Drugs with similar mechanisms of action clustered together.&lt;/p&gt;
Avionic support for the Foreign Military Sales customer (2013)

As military budgets decline, opportunities to maintain economies of scale in weapon system production may increasingly depend upon Foreign Military Sales (FMS). FMS can also spread development costs among all customers, reducing the burden each must bear. A large scale weapon system integrator is in a unique position to observe the trends in FMS. A manufacturer based depot concept can lower up front acquisition costs in favor of higher future support expenditures. This maintenance approach may indeed be economically sound provided specific maintenance cost drivers, such as reliability and false alarm rates, meet their targets. While both domestic and FMS system customers are affected, the longer cycle times for FMS customers increase sensitivity. The Quick Indicator Technical Study (QITS) lifetime support cost analysis tool is used by Boeing to map the viability of support solutions by using historical trends in place of logistical data unavailable until much later in the design cycle. Omitting logistical data procurement for high probability manufacturer depot candidates and ensuring data procurement for high probability organic candidates allows procurement cost savings for the supported system. There is an FMS customer movement toward self sufficiency in the supply chain that may negate any purely economic analysis. Attentive weapon system suppliers should consider these customer requirements for maintenance and supply chain or face disqualification in an increasingly competitive global supplier landscape. Weapon system cost versus support cost in a zero or declining growth market are explored. Various strategies for reducing support costs for both domestic and FMS systems, specifically in the area of avionic repair, are discussed. System support scenarios ranging from total weapon system Original Equipment Manufacturer (OEM) depot support is contrasted against organic support. Hardware and software architectural features that reduce the cost of ownership for both manufacturer and organic support equipment are explored. System data interchange standards and management features are discussed within the context of reducing support cost by enabling transportability.
Necklace-structured high-harmonic generation for low-divergence, soft x-ray harmonic combs with tunable line spacing (2022)

The extreme nonlinear optical process of high-harmonic generation (HHG) makes it possible to map the properties of a laser beam onto a radiating electron wave function and, in turn, onto the emitted x-ray light. Bright HHG beams typically emerge from a longitudinal phased distribution of atomic-scale quantum antennae. Here, we form a transverse necklace-shaped phased array of linearly polarized HHG emitters, where orbital angular momentum conservation allows us to tune the line spacing and divergence properties of extreme ultraviolet and soft x-ray high-harmonic combs. The on-axis HHG emission has extremely low divergence, well below that obtained when using Gaussian driving beams, which further decreases with harmonic order. This work provides a new degree of freedom for the design of harmonic combs-particularly in the soft x-ray regime, where very limited options are available. Such harmonic beams can enable more sensitive probes of the fastest correlated charge and spin dynamics in molecules, nanoparticles, and materials.
Peroxynitrite like Pan? (2005)

Journal Article Peroxynitrite like Pan? Get access Nazareno Paolocci Nazareno Paolocci * Division of Cardiology, Johns Hopkins Hospital, Baltimore, MD, USA *835 Ross Bldg, 720 Rutland Avenue, Baltimore, MD 21205, USA. Tel.: +1 1 410 955 4813; fax: +1 1 410 502 2558. Email address: [email protected] Search for other works by this author on: Oxford Academic PubMed Google Scholar Cardiovascular Research, Volume 67, Issue 2, August 2005, Pages 176–178, https://doi.org/10.1016/j.cardiores.2005.05.030 Published: 01 August 2005 Article history Received: 24 May 2005 Accepted: 31 May 2005 Published: 01 August 2005
3DOM Separator for Rechargeable Lithium Metal Batteries (2010)

Abstract not Available.
A Spherical Array Approach for Simulation of Binaural Impulse Responses using the Finite Difference Time Domain Method (2014)

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Sub-diffusive spatial frequency domain imaging: light scattering as a biomarker (Conference Presentation) (2017)

In spatial frequency domain imaging (SFDI), a spatially modulated intensity pattern is projected on to tissue, with the demodulated reflectance having more superficial sensitivity with increasing spatial modulation frequency. With sub-diffusive SFDI, very high (>0.5 mm-1) spatial modulation frequencies are projected yielding sensitivity to the directionality of light scattering with only few scattering events occurring and sub-millimeter penetration depth and spatial resolution. This technique has been validated in a series of phantom experiments, where fractal distributions of polystyrene spheres were imaged, and through a model based inversion, the size scale distribution versus overall density of these particles could be separated and visualized in spatially resolved maps. With sensitivity to localized light scattering over a wide field of view (11 cm x 14 cm), this technique is being translated for the application of intraoperative breast tumor margin assessment. To test sensitivity to changes in human breast tissue morphology, a cohort of over 30 freshly excised human breast tissue specimens, including adipose, fibroglandular, fibroadenoma, and invasive carcinoma, have been imaged and co-registered to whole specimen histology. Statistical analysis of the distributions of both textual raw reflectance parameters and model based optical properties for each type of tissue will be presented. Furthermore, classification algorithm development and analysis to predicted likelihood of cancer on the surface of the tissue will also be presented. Reflectance maps, optical property maps, and probability likelihood maps of spatially heterogeneous samples with multiple tissue types will also be shown.
PRESENT STATUS AND FUTURE P ROSPECTS FOR T HE H YBRIDOMA T ECHNOLOGY (1981)

SUMMARY A somatic cell genetic technique has recently been developed that makes it possible to obtain very large amounts of homogeneous antibodies and to replenish the supply of the exact same antibodies whenever they are needed. This hybridoma technology has already contributed to major scientific advances and will surely improve the diagnosis and treatment of many diseases. Because the technology itself is relatively simple and inexpensive, it has captured the attention of basic scientists, clinicians, and industrial managers and investors.
Supplementary Table 1 from The Preclinical Pharmacology and Therapeutic Activity of the Novel CHK1 Inhibitor SAR-020106 (2023)

&lt;p&gt;PDF file, 63KB, Kinase inhibitory profile of SAR-020106 at 10 μMa.&lt;/p&gt;
Nanoscale Resistive Memory Device Using SrTiO3 Films (2007)

Resistive-oxide memory cells based on polycrystalline films of Cr-doped SrTiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> have been investigated with regard to next-generation non-volatile memory. Crosspoint cells with an area of 200 × 200nm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> show fast write and erase times (≤ 100ns), endure 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">5</sup> programming cycles and can be programmed with low currents (< 100μA). The weak area dependence of the write and erase current give rise to desirable scaling properties.