gebhart/patrepeval huggingface dataset:
A +10-dBm IIP/sub 3/ SiGe mixer with IM/sub 3/ cancellation technique (2004)

A third-order intermodulation (IM/sub 3/) cancellation technique using a submixer is proposed for a low-power low-distortion mixer. The IM/sub 3/ cancellation is achieved by summing IM/sub 3/ generated in a main mixer and the submixer, which are almost the same amplitude and opposite phase. The mixer was designed to operate at 870 MHz. The proposed technique reduces IM/sub 3/ by 18 dB with a current increase of about 15% and is suitable for low-power applications. The mixer achieved an input-referred third-order intercept point (IIP/sub 3/) of 10 dBm, a gain of 8.7 dB, and an NF of 9.8 dB and dissipates 30 mW from 2.9 V. The IC is fabricated in a SiGe bipolar transistor with f/sub T/= 30 GHz. The IC occupies 1.44 mm/spl times/1.44 mm.
Supplemental Figure 5 from SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells (2023)

&lt;p&gt;Matrigel colony formation assay of FaDu-mock and FaDu-SMAD4 cells treated with PBS or Cetuximab in combination with JNKi (SP600125) or MEKi (U0126) at indicated concentrations for 7 days. (*p&lt;0.05 and **p&lt;0.01 compared to FaDu-mock and FaDu-SMAD4 without MAPK/JNK inhibitor).&lt;/p&gt;
29.1: Invited Paper : Electrical Testing of Roll‐to‐Roll SAIL Manufactured Flexible Display Backplanes (2011)

Abstract HP and Phicot are making a fully roll‐to roll fabricated display for a solar powered wrist display. We have developed methods for electrical testing of display backplanes on flexible substrates which are not bonded to a carrier. This has enabled improvement of yield through rapid electrical test feedback.
Transanal Rectosigmoidectomy Using a Single Port in a Swine Model (2012)

NOTES transanal rectosigmoidectomy using the single port is feasible and safe. Further experimental studies are warranted, especially in human cadaver model.
Augmenting hematoma-scavenging capacity of innate immune cells by CDNF reduces brain injury and promotes functional recovery after intracerebral hemorrhage (2023)

During intracerebral hemorrhage (ICH), hematoma formation at the site of blood vessel damage results in local mechanical injury. Subsequently, erythrocytes lyse to release hemoglobin and heme, which act as neurotoxins and induce inflammation and secondary brain injury, resulting in severe neurological deficits. Accelerating hematoma resorption and mitigating hematoma-induced brain edema by modulating immune cells has potential as a novel therapeutic strategy for functional recovery after ICH. Here, we show that intracerebroventricular administration of recombinant human cerebral dopamine neurotrophic factor (rhCDNF) accelerates hemorrhagic lesion resolution, reduces peri-focal edema, and improves neurological outcomes in an animal model of collagenase-induced ICH. We demonstrate that CDNF acts on microglia/macrophages in the hemorrhagic striatum by promoting scavenger receptor expression, enhancing erythrophagocytosis and increasing anti-inflammatory mediators while suppressing the production of pro-inflammatory cytokines. Administration of rhCDNF results in upregulation of the Nrf2-HO-1 pathway, but alleviation of oxidative stress and unfolded protein responses in the perihematomal area. Finally, we demonstrate that intravenous delivery of rhCDNF has beneficial effects in an animal model of ICH and that systemic application promotes scavenging by the brain's myeloid cells for the treatment of ICH.
A Linear Least-Squares Algorithm for Double-Wiebe Functions Applied to Spark-Assisted Compression Ignition (2014)

An algorithm for determining the four tuning parameters in a double-Wiebe description of the combustion process in spark-assisted compression ignition engines is presented where the novelty is that the tuning problem is posed as a weighted linear least-squares problem. The approach is applied and shown to describe well an extensive data set from a light-duty gasoline engine for various engine speeds and loads. Correlations are suggested for the four parameters based on the results, which illustrates how the double-Wiebe approach can also be utilized in a predictive simulation. The effectiveness of the methodology is quantified by the accuracy for describing and predicting the heat release rate and predicting the cylinder pressure. The root-mean square errors between the measured and predicted cylinder pressures are 1bar or less, which corresponds to 2% or less of the peak cylinder pressure.
Abstract 4868: In vitro and in cellulo mass spectrometry study of TEAD1 palmitoylation (2020)

Abstract The HIPPO pathway plays an important role in cancer progression and one of its essential components are the transcription factor proteins from the TEAD family. The TEAD family consists of 4 different family members (TEAD1-TEAD4) who modulate gene expression through the interaction with co-activator proteins such as YAP1 and TAZ. Recent studies have shown that TEADs are partially palmitoylated. Activity and stability of TEAD proteins are regulated by this modification. Here, we attempt to better understand the palmitoylation status of TEAD proteins in cells. In a first step, we have developed LC/MS/MS-based assays for the detection of palmitoylated TEAD peptides using recombinant TEAD1 protein. Subsequently, we have set out to analyze endogenous TEAD proteins using YAP1 activated malignant mesothelioma H2052 tumor cells. H2052 tumor cells express preferentially TEAD1 protein. TEAD1 was immunoprecipitated from H2052 tumor cells and subjected to peptidic digest and LC/MS/MS analysis. Peptide mapping permitted to confirm the expected site of palmitoylation (cysteine 359 of TEAD1). In addition, novel sites of both palmitoylation and myristoylation were detected on the lysine residue 336 of TEAD1. While these hydrophobic peptides could not be recovered after in-gel digestion of immunoprecipitation enriched TEAD1 of H2052 cells, digestion performed directly on immunoprecipitation beads allowed us to recover those peptides and hence to confirm the existence of TEAD lysine-myristoylation and lysine-palmitoylation in cells. In this study, we show the development of an MS-based strategy to characterize post translational modifications directly on endogenous TEAD1 proteins present in H2052 tumor cells. Citation Format: Armelle Buzy, Olivier Guichard, Jean-Luc Zacchayus, Olivier Venier, Olivier Courtin, Iris Valtingojer, Laurent Debussche, Vincent Mikol, Jean-Claude Guillemot. In vitro and in cellulo mass spectrometry study of TEAD1 palmitoylation [abstract]. In: Proceedings of the Annual Meeting of the American Association for Cancer Research 2020; 2020 Apr 27-28 and Jun 22-24. Philadelphia (PA): AACR; Cancer Res 2020;80(16 Suppl):Abstract nr 4868.
Colon Cancer, Dysplasia, and Surveillance in Patients with Ulcerative Colitis (1987)

Most gastroenterologists and current textbooks1 2 3 recommend that patients who have had widespread ulcerative colitis for 7 to 10 years should be entered into a surveillance program designed to detect colonic dysplasia (precancer). This involves frequent colonoscopies with multiple mucosal biopsies. The recommended frequency of colonoscopy is any time from every year to every three years. Although there is no clear rationale for choosing one interval over another, the Medical Knowledge Self-Assessment Profile, a publication of the American College of Physicians, states that patients with long-term extensive ulcerative colitis should have a colonoscopy every year.4 The argument for surveillance in such . . .
Demonstration of quantum volume 64 on a superconducting quantum computing system (2021)

Abstract We improve the quality of quantum circuits on superconducting quantum computing systems, as measured by the quantum volume (QV), with a combination of dynamical decoupling, compiler optimizations, shorter two-qubit gates, and excited state promoted readout. This result shows that the path to larger QV systems requires the simultaneous increase of coherence, control gate fidelities, measurement fidelities, and smarter software which takes into account hardware details, thereby demonstrating the need to continue to co-design the software and hardware stack for the foreseeable future.
Nitrido and Oxo Complexes of Rhenium(V) (1992)

This chapter contains sections titled: Dichloronirtridobis(triphenylphosphine)rhenium(V),RenCl2(PPh3)2 trans-Ethyxodiiodooxobis(triphenylphosphine)rhenium(V),ReOl2(OEt)(PPh3)2 Iododioxobis(triphenylphospphine)rhenium(V),ReO2I(PPh3)2
Discriminative feature domains for reverberant acoustic environments (2017)

Several speech processing and audio data-mining applications rely on a description of the acoustic environment as a feature vector for classification. The discriminative properties of the feature domain play a crucial role in the effectiveness of these methods. In this work, we consider three environment identification tasks and the task of acoustic model selection for speech recognition. A set of acoustic parameters and Machine Learning algorithms for feature selection are used and an analysis is performed on the resulting feature domains for each task. In our experiments, a classification accuracy of 100% is achieved for the majority of tasks and the Word Error Rate is reduced by 20.73 percentage points for Automatic Speech Recognition when using the resulting domains. Experimental results indicate a significant dissimilarity in the parameter choices for the composition of the domains, which highlights the importance of the feature selection process for individual applications.
Dynamics and Control of the Quadruped Robot : Dynamic Walk by use of the Redundancy of Actuators Caused by the Multiple Touching Legs (1989)

In this paper, the inverse dynamics of the quadruped robot is described which is the base of the trajectory planning and the costrol of the dynamic walk. The distinctive character of the solution described here is the use of the redundancy of actuators obtained by eliminating the constraint forces from the dynamic equations. In concrete terms, two subjects are described. The first is the realization of the control which is expected not to break the constraints. The second is the rotation around the yaw-axis without using yaw-actuators at supporting legs. Furthermore the experiments utilizing Collie-2 are described.
GPT-Free Sensitivity Analysis for Monte Carlo Models (2019)

This paper extends the applicability of the generalized perturbation theory (GPT)–free methodology, earlier developed for deterministic models, to Monte Carlo stochastic models. The objective of the GPT-free method is to calculate nuclear data sensitivity coefficients for generalized responses without solving the GPT response-specific inhomogeneous adjoint eigenvalue problem. The GPT-free methodology requires the capability to generate the eigenvalue sensitivity coefficients. This capability is readily available in several of the state-of-the-art Monte Carlo codes. The eigenvalue sensitivity coefficients are sampled using a statistical approach to construct a subspace of small dimension that is subsequently sampled for sensitivity information using a forward sensitivity analysis. A boiling water reactor assembly model is developed using the Oak Ridge National Laboratory Monte Carlo code KENO to demonstrate the application of the GPT-free methodology in Monte Carlo models. The response variations estimated by the GPT-free agree with the exact variations calculated by direct forward perturbations. The GPT-free method is also implemented in OpenMC and tested with the Godiva model to show its capability and feasibility in the estimation of the energy-dependent sensitivity coefficients for generalized responses in Monte Carlo models. The sensitivity results are compared against the ones acquired by the standard GPT-based methodologies. A higher order of accuracy in the sensitivity estimation is observed in the GPT-free method.
ChemInform Abstract: The Vibrational Spectrum of Isolated AlH‐ 4: An IR Matrix Isolation and ab initio Study. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A functional approach towards the design, development, and test of an affordable dynamic prosthetic foot (2022)

Humanitarian actors involved in physical rehabilitation, such as the International Committee of the Red Cross (ICRC), usually provide their beneficiaries with lower-limb prostheses comprising Solid Ankle Cushion Heel (SACH) feet as these are considered appropriate (price, durability, low profile to fit a majority of patients, appearance) and reliable for all ambulation levels. However, individuals in low-resource settings having higher ambulation abilities would greatly benefit from dynamic prosthetic feet with improved biomechanics and energy storage and release. Some attempts tried to address this increasing need (e.g. Niagara Foot) but most products proposed by large manufacturers often remain unaffordable and unsuitable to the context of low-resource settings. The design requirements and a price target were defined in partnership with the ICRC according to their initial assessment and used as a starting point for the development process and related technological choices. Numerical simulation and modeling were used to work on the design and to determine the required materials properties (mechanical, chemical, wear), and a cost modeling tool was used to select suitable materials and relevant processing routes (price vs. performance). A prosthetic foot comprising an internal keel made of composite materials, a filling foam, and a cosmetic shell with a foot shape was developed. Manufacturing processes meeting the cost criteria were identified and prototype feet were produced accordingly. These were successfully tested using a compression testing system before gait analyses were performed in the laboratory with non-amputees wearing testing boots. After validation in laboratory conditions, the prototype foot was tested in the field (Vietnam) with 11 trans-tibial unilateral amputees, who showed an increased mobility compared with the SACH foot. The collaboration of different research fields led to the development of a prosthetic foot which met the technical requirements determined by the ICRC's specific needs in its field of operation. The materials and selected production processes led to a manufacturing cost of less than 100 USD per part.
Ultrathin nanosheets of aluminosilicate FER zeolites synthesized in the presence of a sole small organic ammonium (2019)

Ultrathin nanosheets (6–8 nm) of aluminosilicate FER zeolites have been successfully synthesized using a sole small organic ammonium (<italic>N</italic>,<italic>N</italic>-diethyl-<italic>cis</italic>-2,6-dimethyl piperidinium, DMP).
Development of Vibration Reduction Motor Control for Series-Parallel Hybrid System (2006)

&lt;div class="htmlview paragraph"&gt;In hybrid electric vehicles, engine starting and stopping occur frequently to provide better fuel economy. Specifically, the structure of the series-parallel hybrid system transmits engine torque pulsations to the driving wheels during engine starting and stopping, which may degrade the quality of the ride. In addition, the quick response of the electric motor can easily cause drivetrain vibration.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;This paper presents a motor control system for a series-parallel hybrid vehicle designed to reduce these vibrations.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The proposed motor control system consists of two parts; one controller functions to compensate the engine torque pulsation during engine starts, and the other controller functions to control torsional vibration of the propeller shaft and drive shaft generated by rapid increases or decreases in driving torque.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The proposed vibration reduction motor control method was added to the motor controller on the first rear wheel drive hybrid vehicle (Lexus GS450h). Experimental results revealed that the new control method effectively reduces the vibrations of the vehicle.&lt;/div&gt;
Enhanced Reliability and Capacity with Multi-TRP Transmission (2022)

In this article, we discuss the evolution of multi-TRP transmission, which consists of several MIMO features of the 5G New Radio standardization. First, we describe the Rel-16 basic multi-TRP fea-ture that mainly targets downlink data channel enhancements and consists of two different frame-works to address both ideal and non-ideal back-haul scenarios. Next, we describe some of the Rel-17 enhancements such as reliability enhancements for downlink control channel, reliability enhancements for uplink data and uplink control channels, beam management enhancements for multi-TRP, and enhancements that address high-speed train deployment with single-frequency network (SFN) transmission. We also briefly describe other multi-TRP related enhancements in Rel-17 such as inter-cell multi-TRP transmission and joint channel state information for multi-TRP schemes.
Localization system using resonant magnetic coupling factor for improving efficiency in wireless power transfer (2015)

Wireless power transfer (WPT) is widely used in portable devices with the advantage of flexibility and convenience. This paper proposes a cooperative multiple coil matrix transmitter (CMCM) structure. This design allows the mobile device receiver coil to be freely placed above the wireless charging pad which can select the appropriate transmitter coils to activate according to the location of the mobile device. The receiver position can be detected by measuring the coupling factor between the transmitter and the receiver coils with a grid searching algorithm. The primary windings selected to be activated for charging are decided by the receiver position.
Metabolomic approach to the exploration of biomarkers associated with disease activity in rheumatoid arthritis (2019)

We aimed to investigate metabolites associated with the 28-joint disease activity score based on erythrocyte sedimentation rate (DAS28-ESR) in patients with rheumatoid arthritis (RA) using capillary electrophoresis quadrupole time-of-flight mass spectrometry. Plasma and urine samples were collected from 32 patients with active RA (DAS28-ESR≥3.2) and 17 with inactive RA (DAS28-ESR<3.2). We found 15 metabolites in plasma and 20 metabolites in urine which showed a significant but weak positive or negative correlation with DAS28-ESR. When metabolites between active and inactive patients were compared, 9 metabolites in plasma and 15 in urine were found to be significantly different. Consequently, we selected 11 metabolites in plasma and urine as biomarker candidates which significantly correlated positively or negatively with DAS28-ESR, and significantly differed between active and inactive patients. When a multiple logistic regression model was built to discriminate active and inactive cohorts, three variables-histidine and guanidoacetic acid from plasma and hypotaurine from urine-generated a high area under the receiver operating characteristic (ROC) curve value (AUC = 0.8934). Thus, this metabolomics approach appeared to be useful for investigating biomarkers of RA. Combination of plasma and urine analysis may lead to more precise and reliable understanding of the disease condition. We also considered the pathophysiological significance of the found biomarker candidates.
Tip-Enhanced Raman Spectroscopy (TERS) for in Situ Identification of Indigo and Iron Gall Ink on Paper (2014)

Confirmatory, nondestructive, and noninvasive identification of colorants in situ is of critical importance for the understanding of historical context and for the long-term preservation of cultural heritage objects. Although there are several established techniques for analyzing cultural heritage materials, there are very few analytical methods that can be used for molecular characterization when very little sample is available, and a minimally invasive approach is required. Tip-enhanced Raman spectroscopy (TERS) is a powerful analytical technique whose key features include high mass sensitivity, high spatial resolution, and precise positioning of the tip. In the current proof-of-concept study we utilized TERS to identify indigo dye and iron gall ink in situ on Kinwashi paper. In addition, TERS was used to identify iron gall ink on a historical document with handwritten text dated to the 19th century. We demonstrate that TERS can identify both of these colorants directly on paper. Moreover, vibrational modes from individual components of a complex chemical mixture, iron gall ink, can be identified. To the best of our knowledge, this is the first demonstration of in situ TERS for colorants of artistic relevance directly on historical materials. Overall, this work demonstrates the great potential of TERS as an additional spectroscopic tool for minimally invasive compositional characterization of artworks in situ and opens exciting new possibilities for cultural heritage research.
In-situ monitoring of the material composition in PBF-LB via optical emission spectroscopy (2023)

Powder bed fusion using a laser beam of metals (PBF-LB/M) is a widely used additive manufacturing (AM) technique that enables the material-efficient fabrication of complex geometries in metallic parts. However, achieving high-quality parts with desired properties heavily depends on variances in the manufacturing process and powder composition, making quality control an indispensable aspect of almost all applications. Today, mainly grayscale imaging or pyrometry are employed, whereas in situ recording of chemical (compositional) information has rarely been done during LBF-LB/M. This pilot study explores the feasibility of in-situ optical emission spectroscopy (OES) for elemental analysis of metallic samples during PBF-LB, at the example of Nd-Fe-B. Our findings suggest that the local emissivity of Fe and Nd lines can serve as a reliable indicator to determine the temperature and elemental concentration in the plasma. The results showed that Online-OES during PBF-LB enables tracking of how Nd content in as-build parts critically depends on the laser parameter used while printing the part.
Hydrolysis Process Optimization and Functional Characterization of Yak Skin Gelatin Hydrolysates (2019)

Yak ( Bos grunniens ) is an animal mainly living on the Tibetan Plateau. Yak skin is a valuable resource that is wasted in the meat production process. This study aimed to prepare yak skin gelatin hydrolysates (YSGH) from yak skin through enzymatic hydrolysis and investigate functional characterization of YSGH. We showed that trypsin was more effective than neutrase, papain, and pepsin in increasing the degree of hydrolysis (DH) of YSGH. The conditions of enzymatic hydrolysis were optimized using central composite design (CCD) and response surface method (RSM), and the highest DH value of 31.96% was obtained. We then analyzed the amino acid compositions and molecular weight distribution of peptides in YSGH. The obtained YSGH exhibited certain antioxidant activity and excellent ACE-inhibitory activity (IC 50 = 0.991 mg/mL). In addition, the solubility (98.79%), emulsification, and foaming properties of YSGH developed here were also evaluated. With these physicochemical and biological functions, YSGH had potential applications in food, pharmaceuticals, and cosmetics as an ingredient.