gebhart/patrepeval huggingface dataset:
Rationalizing Calcium Electrodeposition Behavior by Quantifying Ethereal Solvation Effects on Ca 2+ Coordination in Well-Dissociated Electrolytes (2020)

Ca-ion electrochemical systems have been pushed to the forefront of recent multivalent energy storage advances due to their use of earth-abundant redox materials and their high theoretical specific densities in relation to monovalent or even other more widely explored multivalent-charge carriers. However, significant pitfalls in metal plating and stripping arise from electrolyte decomposition and can be related to the coordination environment around Ca 2+ with both the negatively charged anion and the organic–aprotic solvent. In this study, we apply multiple spectroscopic techniques in conjunction with density functional theory to evaluate the coordination environment of Ca 2+ across a class of ethereal solvents. Through the combination of X-ray absorption fine structure and time-dependent density functional theory, descriptive measures of the local geometry, coordination, and electronic structure of Ca–ethereal complexes provide distinct structural trends depending on the extent of the Ca 2+ –solvent interaction. Finally, we correlate these findings with electrochemical measurements of calcium tetrakis(hexafluoroisopropoxy)borate (CaBHFIP 2 ) salts dissolved within this class of solvents to provide insight into the preferred structural configuration of Ca 2+ electrolytic solutions for optimized electrochemical plating and stripping.
Characterization of photonic crystal coupled waveguides (2003)

An analysis of coupled photonic crystal (PhC) waveguides is presented. Additionally, fabricated planar PhC coupled waveguides are characterized and experimental results are presented. Applications for photonic crystal directional couplers include frequency selective filters, dispersion compensators, and optical switches.
Velocity Profile Measurement on Oscillating Pipe Flow of a Magnetic Fluid by UVP Method. (2001)

This paper presents velocity profile measurements of an oscillatory pipe flow of magnetic fluid by Ultrasonic Velocity Profile (UVP) method. Experiments are performed at Reynols number Rc=367, defined by mean velocity amplitude and a pipe diameter, and non dimensional angular frequency W=4.76. It is shown that velocity amplitude increases in the center of a pipe and decreases in the near wall region under non-uniform magnetic field. The comparison of measured data under non magnetic field with those obtained from the theory of Newtonian-fluid reveals that noticeable discrepancies exist between them.
A General Method for the Preparation of Ethers Using Water‐Resistant Solid Lewis Acids (2006)

This most ethereal of cascades: Water-resistant single isolated Lewis acids within the framework of molecular sieves act as excellent general catalysts for the synthesis of ethers (see scheme). On this basis, an environmentally friendly process has been developed for the preparation of fine chemicals that involves a one-pot Meerwein–Ponndorf–Verley reduction/etherification cascade.
Integrated CMOS Energy Harvesting Converter With Digital Maximum Power Point Tracking for a Portable Thermophotovoltaic Power Generator (2015)

This paper presents an integrated maximum power point tracking system for use with a thermophotovoltaic portable power generator. The design, implemented in 0.35-μm CMOS technology, consists of a low-power control stage and a dc-dc boost power stage with soft-switching capability. With a nominal input voltage of 1 V, and an output voltage of 4 V, we demonstrate a peak conversion efficiency under nominal conditions of over 94% (overall peak efficiency over 95%), at a power level of 300 mW. The control stage uses lossless current sensing together with a custom low-power time-based analog-to-digital converter to minimize control losses. The converter employs a fully integrated digital implementation of a peak power-tracking algorithm, and achieves a measured tracking efficiency above 98%. A detailed study of achievable efficiency versus inductor size is also presented, with the calculated and measured results.
Benzyl Bromomethyl Sulfide (2001)

[15960-81-3] C8H9BrS (MW 217.12)





InChI = 1S/C8H9BrS/c9-7-10-6-8-4-2-1-3-5-8/h1-5H,6-7H2



InChIKey = PSTOVESVKXDXQX-UHFFFAOYSA-N



(introduction of protected mercaptomethyl group via enolate alkylation; synthesis of α-methylene ketones and carboxylic acids2)



Physical Data: bp 65.5–67 °C/0.2 mmHg.



Solubility: sol CH2Cl2, THF.



Preparative Methods: from phenylmethanethiol, paraformaldehyde, and 48% HBr2 or from benzyl chloromethyl sulfide and anhyd HBr.3



Handling, Storage, and Precautions: store cold; use in a fume hood.
Tangential Ligand-Induced Strain in Icosahedral Au13 (2007)

A quantitative comparison of first principles calculations with extended X-ray absorption fine structure and transmission electron microscopy measurements provides strong evidence that Au13 nanocrystals are stabilized in a slightly distorted icosahedral structure by on-top phosphine ligands and a combination of on-top and bridging thiol ligands. Importantly, the ligands change the icosahedral strain (i.e., the radial−tangential bond length ratio) significantly, with the tangential bonds within the Au core exhibiting much more disorder than the radial ones.
1197: AT-Home Efficacy of an Intranasally Administered Melanocortin Receptor Agonist, PT-141, In Men with Erectile Dysfunction (ED) (2004)

You have accessJournal of UrologyPodium, Monday, May 10, 2004, 1:00 - 3:00 pm1 Apr 20041197: AT-Home Efficacy of an Intranasally Administered Melanocortin Receptor Agonist, PT-141, In Men with Erectile Dysfunction (ED) Hunter Wessells, Harin Padma-Nathan, Jacob Rajfer, Robert Feldman, Raymond Rosen, Perry Molinoff, Lisa Diamond, Dennis Earle, and Barbara Powers Hunter WessellsHunter Wessells , Harin Padma-NathanHarin Padma-Nathan , Jacob RajferJacob Rajfer , Robert FeldmanRobert Feldman , Raymond RosenRaymond Rosen , Perry MolinoffPerry Molinoff , Lisa DiamondLisa Diamond , Dennis EarleDennis Earle , and Barbara PowersBarbara Powers View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)38434-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1197: AT-Home Efficacy of an Intranasally Administered Melanocortin Receptor Agonist, PT-141, In Men with Erectile Dysfunction (ED)." The Journal of Urology, 171(4S), p. 316 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 171Issue 4SApril 2004Page: 316 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Hunter Wessells More articles by this author Harin Padma-Nathan More articles by this author Jacob Rajfer More articles by this author Robert Feldman More articles by this author Raymond Rosen More articles by this author Perry Molinoff More articles by this author Lisa Diamond More articles by this author Dennis Earle More articles by this author Barbara Powers More articles by this author Expand All Advertisement PDF downloadLoading ...
Quantum Fluctuations in Josephson Junction Comparators (2002)

We have developed a method for calculation of quantum fluctuation effects, in particular, of the uncertainty zone developing at the potential curvature sign inversion, for a damped harmonic oscillator with arbitrary time dependence of frequency and for arbitrary temperature, within the Caldeira-Leggett model. The method has been applied to the calculation of the gray zone width Delta Ix of Josephson-junction balanced comparators. The calculated temperature dependence of Delta Ix in the range 1.5 to 4.2 K is in virtually perfect agreement with experimental data for Nb-trilayer comparators with critical current densities of 1.0 and 5.5 kA/cm2, without any fitting parameters.
The intestinal factor Tff3 and a miRNA network regulate murine caloric metabolism (2010)

Gene impairment of the genes for three mammalian trefoil peptides resulted in severe gastrointestinal malfunctions. The trefoil peptides also appear involved in caloric metabolism. Monitoring global miRNA expression of Tff3 deficient mice points to an interplay of Tff3 with a miRNA regulatory network. We identified 21 miRNAs that were deregulated when compared to the wild type strain. In silico evaluation indicated that the majority of the 21 miRNA were connected with the metabolic pathway glycolysis/gluconeogenesis' (p=0.032), a signaling pathway including nine target genes Aldh9a1, Aldh2, Pck1, Aldoc, Pgam2, Pck2, Adh4, Adh5, and Fbp1. Association of Tff3 with this metabolic pathway is further supported by the observation that the body mass of adult Tff3 KO mice (five months) showed a clearly reduced weight. Furthermore, the majority of the identified 21 miRNA genes are localized on murine chromosomes 2 and 5 in three clusters (2A1, 2B, 5B3) suggesting a coordinated expression control and function.
Foaming behavior of porous aluminum by heating of precursors of Al-TiH2 powder (2003)

Foamed Aluminum (highly porous Aluminum) was fabricated by powder processing technology. Aluminum (pure Al or Al–7Si alloy) and titanium hydride (TiH2) powders were mixed to prepare a precursor. The Al(–7Si)/TiH2 precursor was consolidated by three different methods (cold compaction, hot compaction and hot extrusion). The hot compaction and hot extrusion temperatures were 673 and 773 K, respectively. The cold compaction pressures were 450 MPa and 800 MPa, and the hot compaction pressure was 160MPa. The Al(–7Si)/TiH2 precursor was heated in an infrared furnace to melt aluminum and to decompose TiH2, which resulted in the H2 gas generation in molten aluminum. In this work, effects of some processing parameters (heating temperature, heating duration, heating rate and aluminum powder composition) on the foaming behavior were investigated. Heating temperature should be in an adequate range. When the heating temperature was low, the precursor did not expand sufficiently. On the other hand, when the heating temperature was high, the precursor shrunk rapidly. The heating rate did not affect the foaming behavior significantly within the present experimental ranges (0.12~0.5K·s−1). When the Al–7Si/TiH2 precursor was heated, the maximum expansion was sustained for a certain period of time, whereas the Al/TiH2 precursor shrunk rapidly.
Inferring the metabolism of human orphan metabolites from their metabolic network context affirms human gluconokinase activity (2012)

Metabolic network reconstructions define metabolic information within a target organism and can therefore be used to address incomplete metabolic information. In the present study we used a computational approach to identify human metabolites whose metabolism is incomplete on the basis of their detection in humans but exclusion from the human metabolic network reconstruction RECON 1. Candidate solutions, composed of metabolic reactions capable of explaining the metabolism of these compounds, were then identified computationally from a global biochemical reaction database. Solutions were characterized with respect to how metabolites were incorporated into RECON 1 and their biological relevance. Through detailed case studies we show that biologically plausible non-intuitive hypotheses regarding the metabolism of these compounds can be proposed in a semi-automated manner, in an approach that is similar to de novo network reconstruction. We subsequently experimentally validated one of the proposed hypotheses and report that C9orf103, previously identified as a candidate tumour suppressor gene, encodes a functional human gluconokinase. The results of the present study demonstrate how semi-automatic gap filling can be used to refine and extend metabolic reconstructions, thereby increasing their biological scope. Furthermore, we illustrate how incomplete human metabolic knowledge can be coupled with gene annotation in order to prioritize and confirm gene functions.
Control of a flexible arm by means of robustified MPC (2009)

This paper proposes the application of advanced control techniques to the main axis movement of a 4-axis strongly non-linear cardiovascular robot, more precisely a flexible arm. Measurements are taken on the motor shaft, consequently involving difficulties on the control of the load because of the flexibility of the mechanical chain. Two advanced control strategies are further compared: an off-line robustified Model Predictive Control (MPC) technique and a state-feedback linear quadratic (LQ) control. The LQ controller is designed in order to damp the resonant modes due to flexible mechanical structure. Its robust stability is a posteriori verified. The robust stability under both unstructured and polytopic uncertainties is explicitly considered in the robustified MPC synthesis.
The growth of Nd:CaWO4 single crystals (2003)

CaWO4 doped with 0.8 % at. Nd (Nd:CaWO4) single crystals were grown from the melt in air by the Czochralski technique. The critical diameter dc = 1.0 cm and the critical rate of rotation ωc = 30 rpm were calculated from hydrodynamic equations for buoyancy-driven and forced convection. The rate of crystal growth was experimentally obtained to be 6.7 mm/h. For chemical polishing, a solution of 1 part saturated chromic acid (CrO3 in water) and 3 parts conc. H3PO4 (85 %) at 433 K with an exposure time of 2 h was found to be adequate. A mixture of 1 part concentrated HF and 2 parts chromic acid at room temperature after exposure for 30 min was found to be a suitable etching solution. The lattice parameters a = 0.52404 (6) nm, c = 1.1362 (6) nm and V0 = 0.312 (2) nm3 were determined by X-ray powder diffraction. The obtained results are discussed and compared with published data.
The Direct, Enantioselective, One‐Pot, Three‐Component, Cross‐Mannich Reaction of Aldehydes: The Reason for the Higher Reactivity of Aldimine versus Aldehyde in Proline‐Mediated Mannich and Aldol Reactions (2005)

Abstract In the proline‐mediated Mannich and aldol reactions of propanal as a nucleophile, the aldimine prepared from benzaldehyde and p ‐anisidine is about 7 times more reactive than the corresponding aldehyde, benzaldehyde, as an electrophile. This higher reactivity of aldimine over aldehyde is attributed to the carboxylic acid of proline protonating the basic nitrogen atom of the aldimine more effectively than the oxygen atom of the aldehyde, an explanation which has been both experimentally and theoretically verified.
Inhibition of iodine-125-labeled human follitropin binding to testicular receptor by epidermal growth factor and synthetic peptides (1986)

Two tetrapeptide sequence homologies between mouse epidermal growth factor precursor (mEGFP) and human follitropin (FSH) were revealed by a computer program that identifies identical residues among polypeptide sequences. The two tetrapeptides, Lys-Thr-Cys-Thr (KTCT) and Thr-Arg-Asp-Leu (TRDL), are present in the hormone-specific beta subunit of FSH from all species studied. These tetrapeptides are not present in the alpha subunit, which is common to all pituitary glycoprotein hormones. Both tetrapeptides are also found in mEGFP, and one tetrapeptide, TRDL, is located within the 53-residue form of mEGF purified from mouse submaxillary glands. Computer-generated hydropathy profiles predicted that both tetrapeptides are located in hydrophilic portions of the FSH beta subunit and that TRDL is in a hydrophilic portion of commercially available mEGF. Therefore, the tetrapeptides might be accessible to receptor binding sites for FSH. We report that mEGF inhibits binding of 125I-labeled human FSH to receptors in testis by 50% (I50) at a concentration of 1.8 X 10(-5) M. No binding inhibition was observed by GnRH or arginine-vasopressin at 10(-4) M, neither of which contain the tetrapeptide sequences. FSH beta subunit, which contains both tetrapeptides, also inhibited binding (I50 = 9 X 10(-8) M) of 125I-labeled human FSH to testis receptor. Thus, it appears that FSH beta subunit and mEGF are capable of inhibiting binding of FSH to testicular FSH receptors, presumably through interactions that include the homologous tetrapeptides. This presumption was supported by the observation that the synthetic tetrapeptides (KTCT or TRDL) were also active in inhibiting binding of 125I-labeled human FSH to testis receptor.
Synthesis and Structure of a Novel Lewis Acid−Base Adduct, (H3C)3SiN3·GaCl3, en Route to Cl2GaN3 and Its Derivatives:  Inorganic Precursors to Heteroepitaxial GaN (1997)

The formation of a novel Lewis acid-base complex between the silyl azide Si(CH(3))(3)N(3) and GaCl(3) having the formula (H(3)C)(3)SiN(3).GaCl(3)()()(1) is demonstrated. The X-ray crystal structure of 1 shows that the electron-donating site is the nitrogen atom directly bonded to the organometallic group. Compound 1 crystallizes in the orthorhombic space group Pnma, with cell dimensions a = 15.823(10) Å, b = 10.010(5) Å, c = 7.403(3) Å, and Z = 4. Low-temperature decomposition of 1 via loss of (H(3)C)(3)SiCl yields Cl(2)GaN(3) (2), which serves as the first totally inorganic (C,H-free) precursor to heteroepitaxial GaN by ultrahigh-vacuum chemical vapor deposition. A volatile monomeric Lewis acid-base adduct of 2 with trimethylamine, Cl(2)GaN(3).N(CH(3))(3) (3), has also been prepared and utilized to grow high-quality GaN on Si and basal plane sapphire substrates. The valence bond model is used to analyze bond lengths in organometallic azides and related adducts.
Triboelectric Nanogenerators Based on Melamine and Self‐Powered High‐Sensitive Sensors for Melamine Detection (2016)

Melamine (Mel) is added illegally to foods and feeds due to its high nitrogen content and high intake, and it causes serious health problems, so it is urgent to build a simple and quick method for detecting Mel in our daily life. In this work, a self‐powered Mel detection method is developed that is based on the newly invented triboelectric nanogenerator (TENG) by using the strong electronegativity property of Mel. In addition, Mel can enhance the electrical output signals of the TENGs by pairing with other triboelectric materials. Thus a high‐sensitive Mel sensor is designed based on polytetrafluoethylene (PTFE) TENG; the output current of TENG increases with the addition of Mel, resulting in largely improved detection limit of Mel with 0.5 ppb and a linear increase range from 1 to 500 ppb. This study not only develops a new type of material for TENG, but also demonstrates an innovative and convenient method for the detection of Mel and other biomaterials.
Effect of processing techniques in controlling the release rate and mechanical strength of hydroxypropyl methylcellulose based hydrogel matrices (1996)

Hydroxypropyl methylcellulose (HPMC, e.g. Methocel® K4M/E4M) is commonly used in formulating sustained release products. The release profiles and mechanical strength of HPMC containing tablets can be affected by the particle size of the polymer. The importance of processing techniques in minimizing the effect of particle size on the release profiles as well as on the mechanical strength of tablets has been emphasized by this study. It was found that the use of hydroalcoholic solvents for granulation can reduce problems such as poor mechanical strength and variation in release profiles arising from particle size differences of HPMC polymers.
Initialization-independent spectral clustering with applications to automatic video analysis (2004)

Popular clustering algorithms, such as K-means (KM) and expectation maximization (EM), are sensitive to the initialization of cluster centers. In contrast, recently proposed K-harmonic means (KHM) algorithm is more robust to the randomness of the initialization. However, KHM works best when the dimensionality of the data (N) is small (usually less than 8). Because the dimensionality of features that are used for many clustering problems in image/video and speech processing is large, the benefits of KHM cannot be exploited. Based upon this observation, this paper proposes a novel method to employ KHM for high-dimensional data so as to realize initialization-independent clustering. The proposed method employs efficient spectral clustering techniques whereby the affinity matrix of the data is decomposed into its eigenvectors and k (total number of clusters) eigenvectors corresponding to the k largest eigenvalues are retained. That is, we represent N-D data by k-D transformed data when k < N and propose to employ KHM over this k-D transformed data. The assumption of k < N indeed encompasses a large number of significant video processing and computer vision problems where the use of KHM was not beneficial before. We demonstrate the effectiveness and the efficiency of the proposed algorithm for face clustering in the domains where the number of persons (k) is not large, such as anchorperson grouping, video-based speaker clustering in videoconferencing, and identity-based tracking in small office environments.
MAPK activation in mature cataract associated with Noonan syndrome (2013)

This case highlights the possible association of cataract formation with MAPK cascade protein upregulation in Noonan syndrome.
Abstract 18012: Insights into the Cardiorenal Syndrome Type II in the Rat (2013)

Cardiorenal Syndrome Type II (CRSII) is kidney function deterioration in the presence of Chronic Heart Failure (CHF). The mechanisms leading to kidney damage in CHF are however still obscure. We studied the development of kidney injury in a model of right CHF monocrotaline (MCT) treated rats. Methods: 10 Sprague-Dawley rats were treated with MCT for 4 weeks until they developed HF. 11 were taken as control (C). Heart failure was confirmed on transverse heart histologic sections looking at RV hypetrophy /dilatation and BNP plasma levels. Cytokine profile was assessed by Multiplex array on sera. pNGAL, pCreatinine (ELISA), kidney tissue NGAL (RT-PCR) were performed. Kidney cell apoptosis was assessed by TUNEL. Results: MCT rats showed higher BNP values (MCT 4.7±1.2 vs C 1.5±0.5pg/mL p&lt;0.004 ), marked RV Hypetrophy and dilatation (RVMass/RVVolume MCT 1.46±0.31vs C 2.4±0.8 p&lt;0.01). TNFα (MCT 1325.37±559.95vsC84.46±64.50 pg/ml ), IL1(MCT183.71±51.61vsC78.31±26.07), IL4 (MCT 731.67±154.83 vs C 316.62±12.55pg/ml), IL6 (MCT 5314.983±1632.98 vs C1754.01±188.85), IL10 (MCT2613.10±934.04vs C847.70±152.19 pg/ml) were all increased (p&lt;0.05) as well as Creatinine (MCT 0.95±0.4 vs C 0.57±0.4 ug/mL, p&lt;0.05). Both plasma (MCT 0.56±0.28 vs C 0.25±0.16 ug/mL,p&lt;0.02) and kidney tissue NGAL (MCT 70.7±8.7vs C 32.1±9.9 AU, p&lt;0.001) were significantly increased and a higher number of kidney apoptotic cells was found (MCT 184.01±47.6 vs C 16.3±11.6 cells/mm2, p&lt; 0.0001). In C rats apoptosis was found only on tubular or vascular cells, while in MCT also a lot of interstitial cells was found. In MCT rats apoptosis was found in medullar part of kidney with focal aspect. Conclusion: CHF in the rat is accompanied by deterioration of kidney function (CRSII). A rise of creatinine and NGAL, an early biomarker of kidney damage, was detected. Kidney cells apoptosis triggered by circulating pro-inflammatory cytokines represent the final insult to the kidney due to the CHF-induced perturbation of neuro-endocrine and inflammatory milieu.