gebhart/patrepeval huggingface dataset:
Spin Coherence in Single NV Centers Coupled to Controllably Assembled Nanopatch Antennas (2019)

We transfer a pre-characterized nanodiamond with a single nitrogen-vacancy (NV) center onto an epitaxial silver substrate and deterministically couple it to a nanopatch antenna. The NV retains its coherent spin dynamics in this process. © 2019 The Author(s)
Sensitivity to Molecular Order of the Electrical Conductivity in Oligothiophene Monolayer Films (2012)

Using conducting probe atomic force microscopy (CAFM), we show that electrical conductivity in oligothiophene molecular films deposited on SiO(2)/Si wafers is extremely sensitive to degree of crystalline order in the film. By locally distorting the molecular order in the films through the controlled application of pressure with the AFM tip, the lateral charge transport was reduced by factors varying from 2 to 10, even when no changes in the height of the film could be observed.
Havyaka Kannada : Modality and negation (1999)

The paper describes for the Havyaka dialect Kannada the expression of modality, against the background of a general theory of modality, then the expression of negation, and finally the relation of the two expression types, more particularly the expression of relative scope. It will be shown that when the modality is epistemic, it is modality that has negation in its scope, independent of the negative strategy that is chosen. When the modality is not epistemic, both scope relations are possible. With a converbal strategy modality has scope over negation. In all other cases but one, negation has scope over modality. The exception concerns the prohibitive imperative, which literally expresses the negation of necessity, yet is taken to express the necessity of a negation. The exception is explained by Gricean pragmatics.
Diagnostic performance of salivary urea nitrogen dipstick to detect and monitor acute kidney disease in patients with malaria (2018)

The SUN dipstick had reasonable sensitivity and excellent specificity when used to diagnose KD in a cohort of patients with malaria in a resource-limited setting. Given the severity of presenting illness and kidney injury, the SUN dipstick diagnostic threshold was high (test pad #5). SUN may be used to detect AKI in patients with malaria in low resources settings, thus facilitating earlier access to adequate treatment, which may improve survival.
Hybrid integration of LiNbO<inf>3</inf> thin films on micromachined Si substrates using room-temperature transfer bonding (2012)

Summary form only given. Hybrid integration of high-quality lithium niobate (LiNbO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> ) single-crystal thin films (<; 5 μm) on micromachined Si substrates has been demonstrated using room-temperature flip-chip transfer bonding based on surface-activated bonding with Au microbumps.
Automatic surrogate model type selection during the optimization of expensive black-box problems (2011)

The use of Surrogate Based Optimization (SBO) has become commonplace for optimizing expensive black-box simulation codes. A popular SBO method is the Efficient Global Optimization (EGO) approach. However, the performance of SBO methods critically depends on the quality of the guiding surrogate. In EGO the surrogate type is usually fixed to Kriging even though this may not be optimal for all problems. In this paper the authors propose to extend the well-known EGO method with an automatic surrogate model type selection framework that is able to dynamically select the best model type (including hybrid ensembles) depending on the data available so far. Hence, the expected improvement criterion will always be based on the best approximation available at each step of the optimization process. The approach is demonstrated on a structural optimization problem, i.e., reducing the stress on a truss-like structure. Results show that the proposed algorithm consequently finds better optimums than traditional kriging-based infill optimization.
Evaluation of Additive Manufacturing for High Volume Composite Part Molds (2017)

ORNL worked with TruDesign, LLC to develop viable coating solutions to enable the use of large scale 3D printing for both low-temperature and high-temperature composite molds. This project resulted in two commercial products and successfully demonstrated the use of printed molds for autoclave processing for the first time.
Reputation in Bargaining and Durable Goods Monopoly (1986)

This paper analyzes durable goods monopoly in an infinite-horizon, discrete-time game. The authors prove that, as the time interval between successive offers approaches zero, all seller payoffs between zero and static monopoly profits are supported by subgame perfect equilibria. This reverses a well-known conjecture of Coase. Alternatively, one can interpret the model as a sequential bargaining game with one-sided incomplete information in which an uninformed seller makes all the offers. The authors' folk theorem for seller payoffs equally applies to the set of sequential equilibria of this bargaining game. Copyright 1989 by The Econometric Society.
Apoptosis inducing ability of silver decorated highly reduced graphene oxide nanocomposites in A549 lung cancer (2016)

Recently, graphene and graphene-based materials have been increasingly used for various biological applications due to their extraordinary physicochemical properties. Here, we demonstrate the anticancer properties and apoptosis-inducing ability of silver doped highly reduced graphene oxide nanocomposites synthesized by employing green approach. These nano composites (PGE-HRG-Ag) were synthesized by using Pulicaria glutinosa extract (PGE) as a reducing agent and were evaluated for their anticancer properties against various human cancer cell lines with tamoxifen as the reference drug. A correlation between the amount of Ag nanoparticles on the surface of highly reduced graphene oxide (HRG) and the anticancer activity of nanocomposite was observed, wherein an increase in the concentration of Ag nanoparticles on the surface of HRG led to the enhanced anticancer activity of the nanocomposite. The nanocomposite PGE-HRG-Ag-2 exhibited more potent cytotoxicity than standard drug in A549 cells, a human lung cancer cell line. A detailed investigation was undertaken and Fluorescence activated cell sorting (FACS) analysis demonstrated that the nanocomposite PGE-HRG-Ag-2 showed G0/G1 phase cell cycle arrest and induced apoptosis in A549 cells. Studies such as, measurement of mitochondrial membrane potential, generation of reactive oxygen species (ROS) and Annexin V-FITC staining assay suggested that this compound induced apoptosis in human lung cancer cells.
On the Relevance of Strategic and Tactical Asset Allocation for Portfolio Insurance (2020)

Portfolio insurance can be an appropriate means to preserve a given capital floor, yet the associated risk budgeting parameters need to be tailored to align with the underlying investment strategy. The main determinants are strategic asset allocation as well as the range and accuracy of tactical asset allocation decisions that would help mitigate downside risk. We evaluate the performance of a multi-asset allocation strategy across a vast number of alternative scenarios using block-bootstrap simulations. Based on a simulated tactical asset allocation model, our framework enables us to gauge the impact of assumed forecast accuracy and the tactical asset allocation range on the ultimate portfolio return distribution under a classic dynamic portfolio insurance risk budgeting framework.
Cyanines comprising barbiturate group facilitate NIR‐light assisted ATRP under anaerobic and aerobic conditions at two wavelengths using Fe(III) catalyst (2021)

Abstract Cyanines with heptamethine pattern namely 5‐(6‐(2‐(3‐ethyl‐1,1‐dimethyl‐1H‐benzo[e]indol‐2(3H)‐ylidene)ethylidene)‐2‐(2‐(3‐ethyl‐1,1‐dimethyl‐1H‐benzo[e]indol‐3‐ium‐2yl) vinyl) cyclo‐hex‐1‐en‐1‐yl)‐1,3‐dimethyl‐2,6‐dioxo‐1,2,3,6‐tetrahydropyrimidin‐4‐olate comprising a barbiturate group facilitate controlled radical polymerization using FeBr 3 in the ppm range applying radiation at 790 nm. Tris(4‐methoylphenyl)phosphine, Tris(2‐pyridylmethyl)amine or tetrabutylammonium bromide served as ligand. The latter showed the best performance resulting in a system needing no amino nitrogen for photo‐ATRP. Ethyl α‐bromophenylacetate worked as initiator. The cyanine interacts with FeBr 3 resulting in a new absorption band at 877 nm that also resulted in formation of polymer exhibiting similar molecular weight but higher dispersity compared to that obtained by 790 nm radiation by exposure with a light‐emitting diode (LED) emitting at 870 nm. This explains the reactivity of the system while other cyanines such as 2‐[2‐[3‐[2‐(1,3‐Dihydro‐1,3,3‐trimethyl‐2H‐indol‐2‐ylidene)‐ethylidene]‐2‐(1‐phenyl‐ 1H‐tetrazol‐5‐ylsulfanyl)‐1‐cyclohexen‐1‐yl]‐ethenyl]‐1,3,3‐trimethyl‐3H‐indolium chloride showed no activity by exposure at 790 nm in combination with FeBr 3 /Br − . Controlled radical polymerization was confirmed by successful chain extension and block copolymerization experiments resulting in polymers, which exhibit a dispersity of about 1.3. Interestingly, the new system comprising the aforementioned barbiturate substituted cyanine, FeBr 3 /Br − and ethyl α‐bromophenylacetate showed a certain oxygen tolerance. Polymers obtained exhibited similar dispersity as those made under inert conditions.
ChemInform Abstract: Microwave‐Assisted Protocols for the Expedited Synthesis of Pyrazolo[1,5‐a] and [3,4‐d]Pyrimidines. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Al-Metyaf (2018)

Colorimetric analysis is a method of determining the concentration of a chemical element or chemical compound in a solution with the aid of a color reagent. This poster explores the utilization of smartphones for colorimetric quantification of biological macromolecules. A low-cost optomechanical device and an Android application were designed to capture the image of a substance sample, and detect its concentration using the Saturation channel from the HSV color space. We report the device design and findings from preliminary experiments.
105 nm Wavelength Conversion of 40-Gb/s DPSK in a Dispersion-Engineered Silicon Waveguide (2013)

We demonstrate wavelength conversion of 40-Gb/s DPSK signals across a 105-nm range in a dispersion-engineered silicon waveguide with 1.83-dB average power penalty, further confirming broadband and format-transparent parametric-processing potential in silicon.
Temporal Stability of Sequential Pulse Defibrillation Threshold (1986)

We have shown that sequential pulse defibrillation threshold voltage and total delivered energy do not change with maturation of the electrode tissue interface for up to 12 weeks after implantation of two different electrode configurations. This result is important to predict the future performance of an implantable defibrillator that is tested only at implant.
Supplementary Figures 1-3 from Urinary TMPRSS2:ERG and PCA3 in an Active Surveillance Cohort: Results from a Baseline Analysis in the Canary Prostate Active Surveillance Study (2023)

&lt;p&gt;PDF - 160K, Supplementary Figure S1. ROC analysis of serum PSA, TMPRSS2:ERG, PCA3, alone and in combination, for prediction of ��34% positive biopsy cores at time of specimen collection. AUC(PSA) does not differ significantly from AUC(TMPRSS2:ERG) P = 0.31, AUC(PCA3) P = 0.21, AUC(TMPRSS2:ERG +PCA3) P = 0.21, or AUC(TMPRSS2:ERG +PCA3+PSA) P = 0.24. Supplementary Figure S2. Multivariable logistic regression analysis for the prediction of high Gleason grade (��7) at time of specimen collection. (A) ROC curve and (B) Odds ratios for each covariate. N = 360 Supplementary Figure S3. Multivariable logistic regression analysis for the prediction of high Gleason grade (��7) at time of specimen collection. Participants with an abnormal DRE were excluded. (A) ROC curve and (B) Odds ratios for each covariate. N = 308.&lt;/p&gt;
Asymptotically optimal time synchronization in dense sensor networks (2003)

We consider the problem of synchronization of all clocks in a sensor network, in the regime of asymptotically high node densities. We formulate this problem as one in which all clocks must line up with the clock of an arbitrary node in the network (of course without assuming that this clock can be observed everywhere in the network, nor assuming that this node has any special hardware--this node could be any). We give a state-space description for the generation of observable data as a function of the ideal clock, and we derive an optimal estimator for determining the state of the ideal clock. A salient feature of our approach is that nodes collaborate to generate an aggregate waveform that can be observed simultaneously by all nodes, and that contains enough information to synchronize all clocks. This aggregate waveform effectively simulates the presence of a "super-node" capable of generating a high-power, network-wide time reference signal.
Recent advances in treatment of spatial neglect: networks and neuropsychology (2023)

Despite promising results from individual studies, significant methodological heterogeneity between trials weakened conclusions drawn from meta-analyses. Improved classification of spatial neglect subtypes will benefit research and clinical care. Understanding the brain network mechanisms of different treatments and different types of spatial neglect will make possible a precision medicine treatment approach.
Pteridines CVII* Synthesis of 6-Azidomethyl-5,6,7,8-tetrahydropterin. Photo degradation Products and Cofactor Properties on Aromatic Amino Acid Monooxygenases (1995)

Summary The synthesis of 6-azidomethyl-5,6,7,8-tetrahydropterin (6-AzmH 4 Ptr) (9) starting from 2,4-diamino- 6-hydroxymethylpteridine (1) is described. A special protecting group strategy had to be applied to perform the structural modifications. The introduction of the azido function was achieved by a Mitsunobu reaction converting the N 2 - N ,N -dimethylaminomethylen-6 -hydroxymethyl-5-pivaloyl-5,6,7 ,8-tetrahydropterin (7) with diphenylphosphoryl azide into the corresponding 6-azidomethyl derivative (8). The newly synthesized compounds have been characterized by elemental analyses, UV, IR and 1 H-NMR spectra. The photolysis of 6-AzmH 4 Ptr (9) and its inactivation effect upon aromatic amino acid mono oxygenases has been studied
Metal–Nitrogen–Carbon Catalysts by Dynamic Template Removal for Highly Efficient and Selective Electroreduction of CO2 (2023)

The renewable electroreduction of CO2 to CO is a key component of future clean energy scenarios. These scenarios allow for the recycling of carbon emissions into value-added chemicals which achieves the joint goal of reducing greenhouse gase(s) while producing valuable chemical product(s). A catalyst which has a high activity and selectivity for the electroreduction of CO2 to CO is highly desired for these applications. Nonprecious metal catalysts (non-PGM) and specifically metal–nitrogen–carbon (M–N–C) catalysts are prime cathode candidates as they are selective for CO and H2 formation with only trace amounts of other products such as CH4. The traditional method of production of atomically dispersed M–N–C proceeds either through a sacrificial poymer approach or through hard-templating the catalyst with silica. The other is through the direct pyrolysis of nonabundant metal macrocycles such as MOF-based precursors via a soft-templating approach. These syntheses have substantial industrial limitations as they require harsh acid or basic solvents for postpyrolytic removal of the support or they require rare chemical precursors. The method herein uses mechanochemical mixing of a fluorine-containing polymer with common pyrolytic precursors for the in situ removal of the template during the first pyrolysis. Further ball-milling and post-treatment in ammonia atmosphere yield a highly selective catalyst for CO2 reduction. The role of the metal center in these M–N–C catalysts in promoting CO2 reduction is explored (M = Fe, Ni, Co, Mn) vs the performance of metal-free N–C. A mechanistic pathway for CO2 reduction on the various M–N–C catalysts is suggested. The champion catalyst in terms of overall selectivity/activity (Ni–N–C) boasts a 98.9 ± 0.2% faradaic efficiency for CO formation (FEco) at −1.1 V vs RHE and an unmatched selectivity for CO2 reduction (FEco > 85%) even at low overpotential (E = −0.3 V vs RHE) compared to traditional Ni–N–C. The catalysts synthesized here present a promising class of electrocatalysts which may be explored for a range of electrocatalytic applications.
Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate (2009)

The pleiotropic lipid mediator sphingosine-1-phosphate (S1P) can act intracellularly independently of its cell surface receptors through unknown mechanisms. Sphingosine kinase 2 (SphK2), one of the isoenzymes that generates S1P, was associated with histone H3 and produced S1P that regulated histone acetylation. S1P specifically bound to the histone deacetylases HDAC1 and HDAC2 and inhibited their enzymatic activity, preventing the removal of acetyl groups from lysine residues within histone tails. SphK2 associated with HDAC1 and HDAC2 in repressor complexes and was selectively enriched at the promoters of the genes encoding the cyclin-dependent kinase inhibitor p21 or the transcriptional regulator c-fos, where it enhanced local histone H3 acetylation and transcription. Thus, HDACs are direct intracellular targets of S1P and link nuclear S1P to epigenetic regulation of gene expression.
Supplementary Table 2 from A Cross-Species Analysis in Pancreatic Neuroendocrine Tumors Reveals Molecular Subtypes with Distinctive Clinical, Metastatic, Developmental, and Metabolic Characteristics (2023)

&lt;p&gt;Supplementary Table 2 contains patient and tumor characteristics of the core clinical samples used in the miR and mRNA profiling.&lt;/p&gt;
Highly Specific, Fluorescent Cannabinoid Type 2 Receptor Probes Enable Applications in Microscopy, Flow Cytometry and FRET-based Binding Assays (2019)

Pharmacological modulation of cannabinoid type 2 receptor (CB2R) holds promise for the treatment of numerous conditions including inflammatory diseases, autoimmune disorders, pain, and cancer. Despite its significance, researchers lack reliable tools to address questions concerning the complex mechanism of CB2R signaling and its downstream consequences, especially in cell-type and tissue-dependent contexts. Herein, we report highly specific CB2R fluorescent probes and their use in a variety of applications: flow cytometry with overexpressing as well as endogenously expressing cells, real-time confocal microscopy of living cells, and a novel FRET-based, CB2R binding assay amenable to high throughput screening.&lt;br&gt;
Pinch-the-sky dome (2010)

Pinch-the-Sky Dome is a large immersive installation where several users can interact simultaneously with omni-directional data inside of a tilted geodesic dome. Our system consists of an omni-directional projector-camera unit in the center of the dome. The projector is able to project an image spanning the entire 360 degrees and a camera is used to track freehand gestures for navigation of the content. The interactive demos include: 1) the exploration of the astronomical data provided by World Wide Telescope, 2) social networking 3D graph visualizations, 3) immersive panoramic images, and 4) 360 degree video conferencing. We combine speech commands with freehand pinch gestures to provide a highly immersive and interactive experience to several users inside the dome, with a very wide field of view for each user.
SUPERMASSIVE BLACK HOLES FROM ULTRA-STRONGLY SELF-INTERACTING DARK MATTER (2015)

We consider the cosmological consequences if a small fraction (f≲0.1) of the dark matter is ultra-strongly self-interacting, with an elastic self-interaction cross-section per unit mass σ≫1 cm^2/g. This possibility evades all current constraints that assume that the self-interacting component makes up the majority of the dark matter. Nevertheless, even a small fraction of ultra-strongly self-interacting dark matter (uSIDM) can have observable consequences on astrophysical scales. In particular, the uSIDM subcomponent can undergo gravothermal collapse and form seed black holes in the center of a halo. These seed black holes, which form within several hundred halo interaction times, contain a few percent of the total uSIDM mass in the halo. For reasonable values of σf, these black holes can form at high enough redshifts to grow to ∼10^9M_⊙ quasars by z≳6, alleviating tension within the standard ΛCDM cosmology. The ubiquitous formation of central black holes in halos could also create cores in dwarf galaxies by ejecting matter during binary black hole mergers, potentially resolving the "too big to fail" problem.
Storage Stability of Ultraviolet Irradiated Hdpe (2008)

The persistence of oxygen-containing groups such as C-O and C=O of ultraviolet irradiated high density polyethylene (HDPE) was investigated by FTIR, water contact angle measurement and measurements of the mechanical properties. The oxygen-containing groups of the irradiated HDPE after storage were still C=O and C-O, and the C=O concentration increased a little compared with that of the irradiated HDPE before storage. The water contact angle of the irradiated HDPE was unchanged after storage, so the hydrophilicity was constant. Compatibilised blends were prepared by using irradiated HDPE as a compatibiliser in HDPE/sericite-tridymite-cristobalite. The compatibilisation effect of the irradiated HDPE was better after storage.
Comparison of the Hemagglutination-Inhibiting and Neutralizing Antibody Responses of Volunteers Given 400 Chick Cell-Agglutinating Units of Influenza A/New Jersey/76 Split-Virus Vaccine (1977)

Thirty-two volunteers 25 years of age or older who were employees of the Laboratory of Infectious Diseases (National Institute of Allergy and Infectious Diseases, Bethesda, Md.) were given 400 chick cell-agglutinating units of influenza A/New Jersey/76 virus vaccine (Wyeth Laboratories, Philadelphia, Pa.) intramuscularly. Sera were assayed for hemagglutination-inhibiting (HAI) and neutralizing antibody before and after inoculation. All 32 subjects had a fourfold rise in titer of HAI antibody, and 25 of 32 had a similar rise in titer of neutralizing antibody. The average log2 rise was 4.5 for HAI antibody and 4.1 for neutralizing antibody. Therefore, this vaccine is believed to be capable of stimulating HAI and neutralizing antibodies to an equal extent.
An Oxidative Entry into the Amido Trioxadecalin Ring System (2003)

The amido trioxadecalin ring system is a key structural component of the architecturally interesting anticancer and immunosuppressive agents of the mycalamide, theopederin, and onnamide families of natural products. We report a new entry into this structure in which a mixed acetal serves as a surrogate for a formaldehyde hemiacetal in an addition to an oxidatively generated acyliminium ion. The stereochemical outcome of this process can be explained by the conformational preferences of the product ring system.
Argonne ARPA-E Battery Research (2011)

Argonne National Laboratory and Envia Systems annouced a licensing agreement for Argonne's patented electrode material technology. Envia plans to commercialize these materials for use in energy storage devices for the next generation of electric, plug-in and hybrid electric vehicles. General Motors Company, LG Chem, BASF and Toda Kyoga have also licensed this suite of Argonne's technologies. For more information visit us at http://www.anl.gov