gebhart/patrepeval huggingface dataset:
IOP and investment in defence and fossil fuel (2022)

Letters criticising the Institute of Physics (IOP) for holding investments in arms companies involved in the nuclear weapons industry, and in fossil fuels.
Postoperative Hyperoxia (60%) Worsens Hepatic Injury in Mice (2014)

Liver injury after ischemia was significantly aggravated by hyperoxia as a consequence of immune cell-mediated oxidative burst. Further studies are needed to elucidate whether routine delivery of high inspirational oxygen concentrations postoperatively should be limited.
Time resolved X-ray Dark-Field Tomography Revealing Water Transport in a Fresh Cement Sample (2016)

Grating-based X-ray dark-field tomography is a promising technique for biomedical and materials research. Even if the resolution of conventional X-ray tomography does not suffice to resolve relevant structures, the dark-field signal provides valuable information about the sub-pixel microstructural properties of the sample. Here, we report on the potential of X-ray dark-field imaging to be used for time-resolved three-dimensional studies. By repeating consecutive tomography scans on a fresh cement sample, we were able to study the hardening dynamics of the cement paste in three dimensions over time. The hardening of the cement was accompanied by a strong decrease in the dark-field signal pointing to microstructural changes within the cement paste. Furthermore our results hint at the transport of water from certain limestone grains, which were embedded in the sample, to the cement paste during the process of hardening. This is indicated by an increasing scattering signal which was observed for two of the six tested limestone grains. Electron microscopy images revealed a distinct porous structure only for those two grains which supports the following interpretation of our results. When the water filled pores of the limestone grains empty during the experiment the scattering signal of the grains increases.
Columella cells revisited: novel structures, novel properties, and a novel gravisensing model. (2000)

A hundred years of research has not produced a clear understanding of the mechanism that transduces the energy associated with the sedimentation of starch-filled amyloplast statoliths in root cap columella cells into a growth response. Most models postulate that the statoliths interact with microfilaments (MF) to transmit signals to the plasma membrane (or ER), or that sedimentation onto these organelles produces the signals. However, no direct evidence for statolith-MF links has been reported, and no asymmetric structures of columella cells have been identified that might explain how a root turned by 90 degrees knows which side is up. To address these and other questions, we have (1) quantitatively examined the effects of microgravity on the size, number, and spatial distribution of statoliths; (2) re-evaluated the ultrastructure of columella cells in high-pressure frozen/freeze-substituted roots; and (3) followed the sedimentation dynamics of statolith movements in reoriented root tips. The findings have led to the formulation of a new model for the gravity-sensing apparatus of roots, which envisages the cytoplasm pervaded by an actin-based cytoskeletal network. This network is denser in the ER-devoid central region of the cell than in the ER-rich cell cortex and is coupled to receptors in the plasma membrane. Statolith sedimentation is postulated to disrupt the network and its links to receptors in some regions of the cell cortex, while allowing them to reform in other regions and thereby produce a directional signal.
Parameter estimation for spatial random trees using the EM algorithm (2004)

A new class of multiscale multidimensional stochastic processes called spatial random trees was recently introduced in J. Pollak et al. (2003). The model is based on multiscale stochastic trees with stochastic structure as well as stochastic states. In this work, we describe a method for estimating the parameters of the process.
Chronic Traumatic Encephalopathy (CTE): A Brief Historical Overview and Recent Focus on NFL Players (2017)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTChronic Traumatic Encephalopathy (CTE): A Brief Historical Overview and Recent Focus on NFL PlayersCraig W. LindsleyCite this: ACS Chem. Neurosci. 2017, 8, 8, 1629–1631Publication Date (Web):August 16, 2017Publication History Published online16 August 2017Published inissue 16 August 2017https://pubs.acs.org/doi/10.1021/acschemneuro.7b00291https://doi.org/10.1021/acschemneuro.7b00291editorialACS PublicationsCopyright © 2017 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views24629Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (1 MB) Get e-AlertscloseSUBJECTS:Central nervous system,Diagnosis,Diseases and disorders,Nervous system diseases,Therapeutics Get e-Alerts
Generation of narrow-bandwidth picosecond visible pulses from broadband femtosecond pulses for femtosecond stimulated Raman (2006)

To perform time-resolved vibrational structural studies with femtosecond stimulated Raman spectroscopy, it is desirable to produce tunable transform-limited picosecond pulses in the visible from a femtosecond laser system. The authors demonstrate here the generation of ∼36cm−1 bandwidth tunable picosecond pulses across the entire visible spectral range using a narrow-bandwidth optical parametric amplifier with chirped pulse pumping. These pulses are characterized and used to obtain broadband stimulated Raman spectra with 38cm−1 resolution.
Interactive complexity control and high-speed stereo matching (2003)

The authors are concerned with the development of a novel approach to edge-based stereo matching. In the context of an incremental matching strategy the authors have replaced the traditional hierarchical (coarse-fine) matching by an approach called complexity control based matching. The implementation of this method allows the user to select interactively features which (given the context provided by previous matches) are most likely to be matched successfully. The selection is done at the resolution of the original image and utilizes a rich set of feature properties (e.g. edge strength, orientation, length, texture etc.), either alone or in logical combinations. Both feature-selection and feature-matching algorithms execute at real-time rates, and all interactions are via a stereo workstation.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Retinal arteriolar vascular reactivity to incremental changes in hyperoxic stimuli during isocapnia (2008)

Abstract Purpose To determine the relationship between the magnitude of retinal arteriolar vascular reactivity and incremental changes in hyperoxic stimuli whilst maintaining isocapnia. Methods Twelve healthy, young adults (mean age 27 years, SD 4) participated in a gas protocol consisting of 4 phases at varying fractional expired oxygen levels (FeO2): baseline (15%), hyperoxia I (40%), hyperoxia II (65%), and recovery (15%). End‐tidal carbon dioxide (ETCO2) was maintained at isocapnia throughout the experiment. Retinal arteriolar diameter, blood velocity, and blood flow were assessed non‐invasively using the Canon Laser Blood Flowmeter during each of these phases. Results Repeated measures ANOVA showed that there were significant influences of incremental changes in FeO2 on retinal arteriolar diameter (p&lt;0.0001), blood velocity (p&lt;0.0001), and blood flow (p&lt;0.0001). Paired t‐tests of these retinal hemodynamic parameters during each phase in the gas sequence showed they were significantly different (p&lt;0.05) from each other, with the exception of baseline and recovery values. Incremental increases in FeO2 caused a linear decrease in group mean arteriolar diameter (R2 = 1, p = 0.002), group mean blood velocity (R2 = 0.9968, p = 0.04), and group mean blood flow (R2 = 0.9982, p= 0.03). Conclusion Isocapnic hyperoxia elicits vasoconstriction and the reduction of retinal arteriolar diameter, velocity and blood flow in a dose‐dependent manner over the range of FeO2 explored in this study. Commercial interest
20‐1: Distinguished Paper: Advanced Hybrid Process with Back Contact IGZO‐TFT (2022)

We propose the new structure of hybrid backplane technology with IGZO‐TFT and LTPS. In this structure, IGZO is directly connected with inter metal to reduce the number of layers. The uniformity of contact resistance between IGZO and metal was less than 20n at G4.5 which is enough for using signal bass line. The characteristics of IGZO‐TFT uniformity and reliability were good enough for mass‐production. The panel with the new hybrid structure backplane has been adopted into practical use as the smartphone with 6.6 inches flexible OLED panel. We believe that the proposed structure would be useful for the mass production of high performance OLED display at low cost production.
Tumor Plasticity Interferes with Anti-Tumor Immunity (2014)

Since tumor cell plasticity was first shown to be crucial in tumor promotion and immune surveillance evasion, it has become an issue of intense investigation. Several mechanisms are associated with the acquisition of tumor cell plasticity and immune evasion, including loss of epithelial phenotype through epithelial-to-mesenchymal transition (EMT). We discuss recent evidence revealing that tumor cell plasticity may lead to the emergence of immunoresistant variants and how the tumor microenvironment evolves to shape this plasticity. We argue that targeting carcinoma cell plasticity represents a novel strategy to better control the emergence of resistant variants and to ensure more effective cancer therapies. In this context, the design of innovative integrative immunotherapy approaches is warranted.
Planing avoidance H design for supercavitating vehicles (2019)

For the planing forces generated when the underwater high speed vehicle's aft end pierces the bubble which lead to oscillatory motion, planing avoidance control was designed based on observer and compensation in this paper. The effect of this compensation is related to the performance of the controller, hence we consider controllers designed via the H∞ feedback control. In the paper, the H∞ performance requirement which lead to the weight selection problem is analysed also. Through the design of the weighted matrix, the H∞ controller that satisfies various performance requirements is obtained. Simulation results show that this H∞ state feedback controller with the compensating observer can avoid the planing force generated. This method of H∞ weighting coefficients and the compensation method of the disturbance observer can also be a reference for other system design as well.
Effects of elastase and cathepsin G on the levels of membrane and soluble TNFα (2005)

Neutrophil elastase (NE) and cathepsin G (CG), the proteolytic enzymes localized in azurophil granules of neutrophils (PMN), are involved in PMN responses to various stimuli. When released at sites of inflammation, they participate in the degradation of numerous proteins involved in the regulation of the immune response. In this study, we employed ADAM17(-/-) fibroblasts stably transfected with cDNA of human pro-tumor necrosis factor alpha (proTNFalpha) (ADAM17(-/-)TNF(+)) to investigate the effects of NE and CG on shedding and degradation of TNFalpha. Both NE and CG were found to diminish the level of membrane TNFalpha (mTNFalpha) as measured by flow cytometry. This process was accompanied by the accumulation of biologically active soluble TNFalpha (sTNFalpha) in the culture medium, as determined by an increase in both the cytotoxic activity of TNFalpha and its ability to serve as a co-stimulator in the induction of inducible nitric oxide synthase (iNOS). However, in contrast to CG, NE at high concentrations was able to degrade sTNFalpha released from the cell surface. Using soluble recombinant human TNFalpha, we identified Val(93)-Ala(94) and Val(117)-Glu(118) as the NE cleavage sites within the sTNFalpha molecule. Taken together, the ability of NE and CG to modulate levels of membrane and soluble forms of TNFalpha may contribute to the proinflammatory activity of neutrophils.
Intumescent PP Blends (2003)

One way to improve the fire performance of polymers is by the development of intumescent systems. The addition of ammonium polyphosphate/polyamide-6 is known to provide flame retardancy in many polymers via an intumescent process. The development of appropriate formulations is limited by their mechanical properties. This study shows that polypropylene based intumescent blends are efficient fire retardant systems and that acceptable mechanical properties can be obtained. It is also shown that adding talc improves the mechanical properties of intumescent polypropylene formulations without decreasing their fire retardancy.
Deep-learning based image reconstruction for MRI-guided near-infrared spectral tomography (2022)

Non-invasive near-infrared spectral tomography (NIRST) can incorporate the structural information provided by simultaneous magnetic resonance imaging (MRI), and this has significantly improved the images obtained of tissue function. However, the process of MRI guidance in NIRST has been time consuming because of the needs for tissue-type segmentation and forward diffuse modeling of light propagation. To overcome these problems, a reconstruction algorithm for MRI-guided NIRST based on deep learning is proposed and validated by simulation and real patient imaging data for breast cancer characterization. In this approach, diffused optical signals and MRI images were both used as the input to the neural network, and simultaneously recovered the concentrations of oxy-hemoglobin, deoxy-hemoglobin, and water via end-to-end training by using 20,000 sets of computer-generated simulation phantoms. The simulation phantom studies showed that the quality of the reconstructed images was improved, compared to that obtained by other existing reconstruction methods. Reconstructed patient images show that the well-trained neural network with only simulation data sets can be directly used for differentiating malignant from benign breast tumors.
260. A Database for Managing Neuromuscular Disease Data in the Province of Quebec (2005)

Use of databases (DB) for managing neuromuscular diseases (NMD) data is an impressive tool for physicians and researchers. We have developed a DB on an Oracle platform. Oracle has a solid architecture witch is only limited by the operating system (OS) and contrast to 4Gb for Microsoft Access DB. Oracle is a multi-OS compatible and includes powerful tools like data mining, data warehousing and for web application development. Oracle is also more secure and more stable than other majors DBMS. For security, this database is located on the Qu|[eacute]|bec Health Department secure intranet and communications between client and server is secured via 128-bits encryption. This intranet is secured from the internet by high-end firewalls and VLAN. With this secure intranet, clinics around province can communicate with database. Each clinical center can store their nominative information in a separate directory not accessible by others clinics for data confidentiality.
Mapping of the X-breakpoint involved in a balanced X;12 translocation in a female with mild mental retardation. (1997)

Balanced chromosomal abnormalities such as translocations and inversions have been identified in many genetic diseases. Cloning of the breakpoints involved in these abnormalities has led to the identification of the disease-related genes. Recent reports suggest the presence of a mental retardation locus at Xq11-12. We have identified a female patient with a balanced translocation t (X;12) (q11;q15) associated with mild mental retardation. We identified a yeast artificial chromosome spanning the X-chromosome breakpoint by using fluorescent in situ hybridization techniques. A cosmid library of this YAC has been constructed and the search for candidate genes is in progress.
Polarization and Photometric Methods in Machine Vision. (1996)

Abstract : Described in this report are designs for polarization camera sensors that have been built to automatically sense partially linearly polarized light, and computationally process this sensed polarization information at pixel resolution to produce a visualization of reflected polarization from a scene, and/or, a visualization of physical information in a scene directly related to sensed polarization. The research performed on polarization-based methods in computer and machine vision provides a new powerful medium for object feature extraction with tremendous versatility and a broad range of applications. The fundamental principles behind these polarization methods developed under this effort are easy to implement with the simple addition of a linear polarizing filter to a standard off the shelf camera sensor. We present a fully automatic polarization camera using liquid crystal technology. Not only are polarization-based feature extraction methods passive, but they require little prior knowledge about the world environment. This makes polarization-based methods applicable beyond just the controlled environments of machine vision.
Electrochemical Reduction of Carbon Dioxide Catalyzed by Cofacial Dinuclear Metalloporphyrin (2003)

Electroreduction of carbon dioxide was homogeneously carried out using cofacial dinuclear metalloporphyrin CoTMPyP-MTPPS. The reduction was catalyzed by Co(I)TMPyP which generated at −1.8 V vs. Ag/Ag+. More excellent catalytic activity was observed in the presence of H2O in comparison with that for mononuclear one. The catalytic activity depended on the central metal of TPPS because they worked as an electron mediator.
Telocytes express ANO‐1‐encoded chloride channels in canine ventricular myocardium (2019)

Telocytes are present in the canine ventricle and express ANO-1. These data merit further study to elucidate the functional expression of these channels in the heart and whether they may be targets for cardiac arrhythmias.
Replication Data for Symmetry-protected topological exceptional chains in non-Hermitian crystals Dataverse (2023)

The Dataverse Project is an open source software application to share, cite and archive data. Dataverse provides a robust infrastructure for data stewards to host and archive data, while offering researchers an easy way to share and get credit for their data.
Atypical Variants of Right Ventricular Outflow Arrhythmias (2014)

In patients with atypical forms of RVOT VT, careful mapping and ablation of the myocardial sleeves near the pulmonic valve can eliminate the arrhythmia.
Narrow-Beam, 4.7 μm-Emitting Near-Resonant Leaky-Wave-Coupled Quantum Cascade Laser Phase-Locked Array (2017)

Narrow beam (3.2 x D.L. FWHM) is demonstrated up to 5.85 W pulsed output power from a five-element phase-locked array of 4.7 μm-emitting quantum cascade lasers. Devices are fabricated by a two-step MOCVD process and operate predominately in an in-phase array mode, in agreement with design simulation studies.
Three-dimensional EEG source imaging via maximum entropy method (2002)

Electroencephalographic imaging or the estimation of three-dimensional dipole current sources on the cortical surface from scalp measured potential distribution is a highly underdetermined inverse problem as there are many 'feasible' images which are consistent with the EEG data. Here, the authors explore the maximum entropy approach to obtain better solutions to this problem. This estimation technique selects that image from the possible set of feasible images which is maximally smooth and most likely to give rise to the measured potential field. The authors have also incorporated a noise-rejection mechanism in their scheme that allows them to estimate the noise component of the recorded potentials. Computer simulation demonstrates that the proposed method can reconstruct three-dimensional current distribution where the conventional least-squares minimum-norm method fails. A preliminary testing of this method on evoked potential data measured during visual checkerboard stimulation at 3 Hz yielded sources largely concentrated in the posterior areas of the brain including a region roughly corresponding to the primary visual cortex.
Proceedings of the 8th International Conference on Automotive User Interfaces and Interactive Vehicular Applications (2016)

Not so long ago in-vehicle human-machine interaction could be considered a settled affair: people knew how to operate the steering wheel and pedals, they knew how to shift gears, and they could tune their radios. Then came mobile phones, and everything started to change. Drivers wanted to do more than just drive . they wanted to chat with their friends, and soon they wanted their cars to provide the types of information and entertainment that had previously been available only in their homes and offices. Today, as a result of spectacular advances in ubiquitous computing, drivers have myriad sources of information and entertainment at their disposal. However, in-vehicle human-machine interaction is anything but a settled affair. This fact provided the impetus for organizing the AutomotiveUI conference series. AutomotiveUI, the International Conference on Automotive User Interfaces and Interactive Vehicular Applications, brings together researchers and practitioners interested in the technical and the human aspects of in-vehicle user interfaces and applications.
A Role for the Vascular Endothelium in Post–Acute COVID-19? (2022)

hile the war against acute coronavirus disease 2019 (COVID-19) is still raging, reports of a long-lasting post-COVID-19 syndrome are surging. "Long COVID" progressed from a mere oddity to an acknowledged public health issue worldwide. A formal definition of post-acute COVID-19 syndrome (ie, long COVID) is evolving, and for the purposes of this review, we consider it as persistent symptoms or complications lasting more than 30 days after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Symptoms of long COVID involve multiple organs and include shortness of breath, fatigue, chest pain, loss of taste and/or smell, and cognitive dysfunction. Studies investigating the incidence of long COVID report broad heterogeneity (likely attributable to variations in study cohorts and long COVID definition/symptoms), and its manifestation may range from 30% to a staggering 80% of all SARS-CoV-2infected patients. Although there is hope that vaccination may reduce the risk of developing long COVID, studies remain inconclusive thus far. Breakthrough infections frequently occur in vaccinated people and may unfortunately still cause an escalation in long COVID cases. Detection and treatment of long COVID is challenging because the molecular underpinnings of the condition remain largely unknown.