1362 NOCTURIA CORRELATES WITH BLADDER AND SYSTEMIC ISSUES AND INCREASES MORTALITY IN PATIENTS WITH TYPE 2 DIABETES (2013)

You have accessJournal of UrologyUrodynamics/Incontinence/Female Urology: Incontinence, Evaluation & Therapy (III)1 Apr 20131362 NOCTURIA CORRELATES WITH BLADDER AND SYSTEMIC ISSUES AND INCREASES MORTALITY IN PATIENTS WITH TYPE 2 DIABETES Yao-Chi Chuang, Min-Shen Chung, Wei-Chia Lee, Rue-Tsuan Liu, and Michael Chancellor Yao-Chi ChuangYao-Chi Chuang Kaohsiung, Taiwan More articles by this author , Min-Shen ChungMin-Shen Chung Kaohsiung, Taiwan More articles by this author , Wei-Chia LeeWei-Chia Lee Kaohsiung, Taiwan More articles by this author , Rue-Tsuan LiuRue-Tsuan Liu Kaohsiung, Taiwan More articles by this author , and Michael ChancellorMichael Chancellor Royal Oat, MI More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2716AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Nocturia has been associated with overactive bladder (OAB). We evaluate the correlates of nocturia independent of OAB, and subsequent mortality in patients with type 2 diabetes. METHODS A self-administered questionnaire containing OAB symptom score (including nocturia score 0-3) was obtained from subjects with type 2 diabetes at a dedicated diabetic center. Nocturia and severe nocturia were defined as rising 2 or more times per night to void, and rising 3 or more times per night to void, respectively. Patient characteristics and diabetes associated complications to risk of nocturia were evaluated. RESULTS Of 1,301 consecutive subjects, 59.6% and 25.3% reported having nocturia and severe nocturia, respectively. The presence and severity of nocturia increased with age. After adjustment for age, duration of DM and the presence of OAB, stroke, calcium channel blocker use, hypertension, abnormal waist circumference, diabetic kidney disease (albuminuria, high serum creatinine level, and low eGFR), and higher level of hsCRP, were associated with nocturia and severe nocturia. Higher BMI and female gender are risk factors for nocturia, and coronary heart disease and higher level of uric acid are risk factors for severe nocturia. The patients with severe nocturia has higher mortality rate than the other group (6.1% vs 2.4%, p=0.001) in 3 years follow-up. CONCLUSIONS Nocturia is highly prevalent in type 2 diabetes. Systemic factors including stroke, hypertension, obesity and diabetic kidney disease are risk factors of nocturia independent of OAB. Severe nocturia increases mortality rate and bladder dysfunction may not be the only cause of nocturia. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e557 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Yao-Chi Chuang Kaohsiung, Taiwan More articles by this author Min-Shen Chung Kaohsiung, Taiwan More articles by this author Wei-Chia Lee Kaohsiung, Taiwan More articles by this author Rue-Tsuan Liu Kaohsiung, Taiwan More articles by this author Michael Chancellor Royal Oat, MI More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...