gebhart/patrepeval huggingface dataset:
Towards Speech Acquisition in Natural Interaction on ASIMO (2010)

The standard approach for teaching robots to communicate via speech is by providing the structure, statistics, and semantics of speech through a supervised, offline learning process. This process imposes constraints like a high degree of specialization to certain, predefined tasks. The resulting system is very rigid and lacks the ability to acquire new skills (e.g. words and their semantics). In contrast to this, children acquire language through observation of adults’ speech and, more importantly, in interaction with them. As a result their speech capabilities are very flexible and can adapt to new situations. Our research target is therefore to build a system that can learn to acquire speech in interaction with humans. The interaction aspect requires a hardware platform that can engage in a natural communication with humans in real-world environments. For this purpose we employ our humanoid robot ASIMO (see Fig. 1). To provide the robot with human-like speech communication abilities we are working on several aspects of sound processing, scene representation, and learning that will be outlined in more detail in the next sections.
An Additional Example of Autoanti‐M (1980)

A sixth example of a potent autoanti-M is described in a nongravida, nontransfused Caucasian woman. The anti-M was still present after a period of 12 months without any apparent cause.
Quantification of Amines in Refinery Process Water via Surface-Enhanced Raman Spectroscopy (2023)

Amines are used in crude oil production, natural gas recovery, and hydrocarbon refining as hydrogen sulfide scavengers, corrosion inhibitors, and pH control neutralizers. Residual amines can be detrimental to the refining process, such as forming heat-stable salts that lead to corrosion-inducing deposits or causing nitrification of wastewater streams. Traditional methods for amine analysis such as ion chromatography are complex, time-consuming, and not adapted to field deployment. We present a new method using surface-enhanced Raman spectroscopy for amine quantification with a focus on two problem-causing tramp amines: monoethanolamine and methylamine. This method is calibration-free, accurate across spectrometers, stable over years in laboratory-standard solutions and in real-world process samples, and can be performed by minimally trained operators within less than 5 min.
Large-field-of-view Chip-scale Talbot-grid-based Fluorescence Microscopy (2012)

The fluorescence microscope is one of the most important tools in modern clinical diagnosis and biological science. However, its expense, size and limited field-of-view (FOV) are becoming bottlenecks in key applications such as large-scale phenotyping and low-resource-setting diagnostics. Here we report a low-cost, compact chip-scale fluorescence-imaging platform, termed the Fluorescence Talbot Microscopy (FTM), which utilizes the Talbot self-imaging effect to enable efficient fluorescence imaging over a large and directly-scalable FOV. The FTM prototype has a resolution of 1.2 microns and an FOV of 3.9 mm x 3.5 mm. We demonstrate the imaging capability of FTM on fluorescently labeled breast cancer cells (SK-BR-3) and HEK cells expressing green fluorescent protein.
Synthesis and Synthetic Application of α-Formylvinylphosphonates. Facile Synthesis of Phosphono-Substituted Heterocyclic Compounds (2000)

The beta-ethoxy-alpha-phosphonovinyl anion, generated from beta-(ethoxy)vinylphosphonate 1 and LDA, reacted with aldehydes and ketones or phenyl isocyanate to give the corresponding allylic alcohols 2a-m or 1,3-diphenyl-5-phosphonouracil 4 in good or moderate yields. Treatment of the alcohols 2a-d,g,h,j with trifluoroacetic acid led to alpha-formylvinylphosphonates 5a-d,g,h,j in excellent yields. Synthetic application of the alpha-formylvinylphosphonates 5a-d,g,h to phosphono-substituted heterocyclic compounds was studied.
P2DAP — Sybil Attacks Detection in Vehicular Ad Hoc Networks (2011)

Vehicular ad hoc networks (VANETs) are being increasingly advocated for traffic control, accident avoidance, and management of parking lots and public areas. Security and privacy are two major concerns in VANETs. Unfortunately, in VANETs, most privacy-preserving schemes are vulnerable to Sybil attacks, whereby a malicious user can pretend to be multiple (other) vehicles. In this paper, we present a lightweight and scalable protocol to detect Sybil attacks. In this protocol, a malicious user pretending to be multiple (other) vehicles can be detected in a distributed manner through passive overhearing by s set of fixed nodes called road-side boxes (RSBs). The detection of Sybil attacks in this manner does not require any vehicle in the network to disclose its identity; hence privacy is preserved at all times. Simulation results are presented for a realistic test case to highlight the overhead for a centralized authority such as the DMV, the false alarm rate, and the detection latency. The results also quantify the inherent trade-off between security, i.e., the detection of Sybil attacks and detection latency, and the privacy provided to the vehicles in the network. From the results, we see our scheme being able to detect Sybil attacks at low overhead and delay, while preserving privacy of vehicles.
PHY Error Models for ns-2 Simulation of FSO Packet Networks over Turbulence Channels (2018)

We propose a framework on the construction of physical (PHY) layer error models for free-space optical (FSO) networks over turbulence-induced fading channels. The constructed PHY error models can be used for simulation study and performance evaluation of various upper-layer protocols over FSO networks using the popular network simulator ns-2. In particular, two-state and multi-state Markov chain models are considered for the FSO links with single- and multi-rate transmission schemes under the impact of atmospheric turbulence conditions. We confirm the effectiveness of the proposed framework and demonstrate the simulation study of several popular protocols, including the Transmission Control Protocol (TCP) and Automatic Repeat reQuest (ARQ), over FSO networks.
Radiative decay and carrier relaxation in annealed InAs/GaAs self-assembled quantum dots (2001)

We have investigated the carrier relaxation and radiative decay in a series of annealed InAs/GaAs self-assembled quantum dots deposited at a low growth rate. The annealed samples retain their dot-like character, the ground state blueshifts and there is a decrease in the energy separation of the optical transitions from 68 meV to 19 meV. The photoluminescence (PL) transients have fast rise times consistent with rapid inter-level relaxation. Radiative lifetimes of the different states can be deduced from the transients providing they are normalised using time resolved photoluminescence. We believe that spin must be conserved during the inter-level scattering. As the dot composition and size changes the radiative lifetimes of the ground and first excited states decrease significantly and we attribute this trend to a combination of a shift in the emission energies and an increase in the overlap of the electron and hole wavefunctions.
Some Directions Out of Usual Paths for Performance Improvement of Batteries (2017)

International audience
Molecular inhibition of cancer cell invasion and metastasis. (1991)

A group of coordinated cellular processes, not just one gene product, is responsible for invasion and metastasis, the most life-threatening aspect of cancer. It is now recognized that negative factors may be just as important as positive elements. Genetic changes causing an imbalance of growth regulation lead to uncontrolled proliferation necessary for both primary tumor and metastasis expansion. However, unrestrained growth does not, by itself, cause invasion and metastasis. This phenotype may require additional genetic changes. Thus, tumorigenicity and metastatic potential have both overlapping and separate features. Invasion and metastasis can be facilitated by proteins which stimulate tumor cell attachment to host cellular or extracellular matrix determinants, tumor cell proteolysis of host barriers, such as the basement membrane, tumor cell locomotion, and tumor cell colony formation in the target organ for metastasis. Facilitory proteins may act at many levels both intracellularly and extracellularly, but are counterbalanced by factors which can block their production, regulation or action. A common theme has emerged: in addition to loss of growth control, an imbalanced regulation of adhesion, proteolysis, and motility appears to be required for invasion and metastasis. Re-equilibrating the expression of the genes involved in these tumor invasion related events could potentially constitute the basis for new anti-cancer therapeutic strategies.
Nonparametric polyspectral estimators for kth-order (almost) cyclostationary processes (1994)

Second- and higher-order almost cyclostationary processes are random signals with almost periodically time-varying statistics. The class includes stationary and cyclostationary processes as well as many real-life signals of interest. Cyclic and time-varying cumulants and polyspectra are defined for discrete-time real kth-order cyclostationary processes, and their interrelationships are explored. Smoothed polyperiodograms are proposed for cyclic polyspectral estimation and are shown to be consistent and asymptotically normal. Asymptotic covariance expressions are derived along with their computable forms. Higher than second-order cyclic cumulants and polyspectra convey time-varying phase information and are theoretically insensitive to any stationary (for nonzero cycles) as well as additive cyclostationary Gaussian noise (for all cycles).< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Memory polynomial with shaped memory delay profile and modeling the thermal memory effect (2013)

This paper presents a proposal for a new memory polynomial modeling technique with non-uniform delay taps to capture the thermal memory effects in power amplifiers. In the proposed modeling structure, each order of the memory polynomial is assigned a different memory delay. The delay profile is an exponentially shaped function, instead of equal unit delays for all memory polynomial branches. Three different metrics, the memory effect modeling ratio (MEMR) and the normalized mean square error (NMSE) and spectrum error (SE) are used to benchmark the proposed exponentially shaped delay profile memorial polynomial model performance against previously published models, namely the memoryless, the unit delay and sparse delay memory based polynomial models. The model coefficients of four models are extracted for three different excitation signals, which were selected as a 64-QAM signal around 2.14 GHz with 20 kHz, 30 kHz and 40 kHz bandwidths, ensuring that the thermal memory effects dominate the electrical memory effects. It is shown that the proposed model outperforms all the previously published models for all three excitation signals used in the experiment.
An ultrastructural study on the multinucleation process of mouse alveolar macrophages induced by 1α,25-dihydroxyvitamin D3 (1987)

The multinucleation process of isolated alveolar macrophages induced by 1 alpha,25-dihydroxyvitamin D3 [1 alpha,25(OH)2D3] was examined using a scanning electron microscope (SEM) and a transmission electron microscope (TEM). At the beginning of culture, most of the macrophages were spherical in shape. During incubation with 1.2 X 10(-8) M 1 alpha,25(OH)2D3, spreading macrophages appeared among the spherical macrophages, and they increased in number. Spreading macrophages extended many cytoplasmic processes toward adjacent macrophages, and interdigitations of these processes between those of neighboring cells were often seen. Two types of cell contact have been observed in the 1 alpha,25(OH)2D3-treated cells. In some, cytoplasmic processes were put into the cytoplasm of the adjacent cells, where clathrinlike structures were observed at the inner membrane of the concave portion. In others, spreading macrophages occasionally came in contact with adjacent cells by a peripheral rim of their cytoplasm with gap junctions. Cytoplasmic continuity was rarely observed at the boundaries between the closely associated cells. The two types of cell contact were also found, though not frequently, in the untreated cells. These results indicate that 1 alpha,25(OH)2D3 promotes multinucleation of alveolar macrophages through spreading forms with the formation of gap junctions and the coated membrane invagination.
Integration across Time Determines Path Deviation Discrimination for Moving Objects (2008)

Human vision has long been known to integrate information across space in order to solve spatial tasks such as judgment of orientation or position. Here we demonstrate an intriguing mechanism which integrates direction information across time in order to optimize the judgment of path deviation for moving objects.
Vesicular Location and Transport of S100A8 and S100A9 Proteins in Monocytoid Cells (2015)

We show here, by using surface biotinylation, followed by Western blotting or surface plasmon resonance analysis, that very low levels of S100A8 and/or S100A9 can be detected on the surface of THP-1 cells or freshly isolated human monocytes. This was supported by immune-electron microscopy where we observed membrane-associated expression of the proteins restricted to small patches. By using confocal microscopy we could determine that S100A8 and S100A9 protein in THP-1 cells or freshly isolated human monocytes was mostly present in vesicular structures. This finding was confirmed using immune-electron microscopy. Subcellular fractionation and confocal microscopy showed that these vesicular structures are mainly early endosomes and endolysosomes. Our subsequent studies showed that accumulation of S100A8 and S100A9 in the endolysosomal compartment is associated with induction of their release from the cells. Furthermore, an inhibitor of lysosomal activity could modulate the release of S100A8 and S100A9 in the extracellular milieu. Our current results suggest that the S100A8 and S100A9 proteins are primarily associated with certain kinds of cytosolic vesicles and may be secreted via an endolysosomal pathway.
Flavonoids as Cycline-Dependent Kinase Inhibitors: Inhibition of cdc 25 Phosphatase Activity by Flavonoids Belonging to the Quercetin and Kaempferol Series (2001)

In an effort to detect potential inhibitors of cdc25 phosphatase, nineteen flavonoids belonging to the quercetin and kaempferol series have been evaluated, using a colorimetric assay of recombinant human cdc25A tyrosine phosphatase as a cell cycle-specific target. Compounds bearing two benzyl or methyl groups in positions 7 and 4' and acetyl on the hydroxy groups of the sugar moiety showed the maximal activity.
Somatostatin Receptor-Targeted Anti-Cancer Therapy (2010)

Somatostatin receptors (SSTRs), especially SSTR subtype 2, are found expressed at relatively higher levels in many tumor cells and in tumoral blood vessels relative to normal tissues. This creates an opportunity for developing various cytotoxic SST conjugates that selectively target SSTR2-specific sites. Accordingly, some potent chemotherapeutic agents such as camptothecin (CPT), methotrexate (MTX), paclitaxel (PTX) and doxorubicin (DOX) have been coupled to SSTR2-preferential somatostatin (SST) analogs. These new cytotoxic SST conjugates display significant SSTR-selective anti-tumor abilities in many different types of tumors. For instance, the CPT-SST conjugate JF-10-81, in which CPT is coupled to the N-terminus of a SSTR2-specific SST analog (JF-07-69), had wide ranging anti-tumor and anti-angiogenic ability. This conjugate also showed an ability to overcome multi-drug resistance (MDR) in SSTR-over-expressing and CPT-insensitive human pancreatic carcinoid BON cells. Notably, another DOX-SST conjugate, AN-238, made by coupling pyrrolino-DOX to the SST analog RC-121, displayed indirect anti-tumor activity against SSTR-negative, non-small cell lung cancer H-157 tumor growth by directly targeting SSTR-positive tumoral vessels of host mice. These cytotoxic SST conjugates should deliver chemotherapeutic agents to receptor-specific sites, enhance anti-tumor efficacy, reduce toxic side effects to normal tissues, and to some extent, overcome MDR. These and other peptide conjugates may possibly represent a newer generation of receptor-targeted cancer therapeutics. This review discusses the progress with reference to SST-based and SSTR-selective cytotoxic cancer therapy.
New approaches to allergen-specific immunotherapy (ASIT): development of a recombinant vaccine against birch pollen allergy (2022)

Новые подходы к аллерген-специфической иммунотерапии (АСИТ): разработка рекомбинантной вакцины от аллергии на пыльцу березы 1 Федеральное государственное бюджетное учреждение «Государственный научный центр «Институт иммунологии» Федерального медико-
Strongly homotopy lie algebras (1995)

(1995). Strongly homotopy lie algebras. Communications in Algebra: Vol. 23, No. 6, pp. 2147-2161.
Acellular vaccines for preventing whooping cough in children (2011)

Multi-component acellular pertussis vaccines are effective, and show less adverse effects than whole-cell pertussis vaccines for the primary series as well as for booster doses.
Suppression of Signals from the Probe in NMR T1, Measurements (1988)

Abstract A simple method is described for accurately measuring spin lattice relaxation times in the presence of large probe background resonances. The method relies on selectively exciting those spins which are In the center of the rf coil, by employing pulse schemes which were developed for surface coil studies. The accuracy of the technique is checked by measurements on camphor in the solid state. Key Words: NMR, spin lattice relaxationbackground signals
Diverse restoration requirements guaranteed shared recovery scheme in optical mesh networks (2003)

We propose a novel shared recovery scheme, which is cost efficient restoration, to satisfy diverse restoration requirements by introducing multiple classes in IP over WDM networks. First, we classify the class of restoration for a lightpath setup request at an ingress node. Then we calculate the backup route for the requested lightpath and reserve the spare resource which shares among the backup paths with different class. We also propose a sharing group (SG) concept based on the wavelength manager (WM) to efficiently manage wavelengths on each link. The diverse restoration requirements are satisfied in terms of restoration time and blocking rate according to the given three classes.
Hydrogen termination of Si(110) surfaces upon wet cleaning revealed by highly resolved scanning tunneling microscopy (2005)

The surface structure of the hydrogen-saturated Si(110) surfaces after wet cleaning is studied on an atomic scale by means of scanning tunneling microscopy. When a surface oxide layer is stripped using a HF-containing solution, the surface consists of nanometer-scaled terraces and atomic steps along various directions. Coupled monohydride lines are formed inside a small terrace, as predicted by infrared spectra. The Si(110) surface after subsequent rinsing for a short period is occupied by a long terrace along the [1¯10] direction in which the ideal 1×1 structure is formed. Atomic arrangements around step edges are determined in detail based on atomic images and first-principles calculations. A ridge-shaped structure is observed after excess rinsing with water, and infrared spectra indicate that the slope is composed of (111) microfacets. From these results, we present the mechanism underlying the formation of the hydrogen-terminated Si(110) surfaces during wet cleaning processes.
Development of a custom on-line ultrasonic vapour analyzer and flow meter for the ATLAS inner detector, with application to Cherenkov and gaseous charged particle detectors (2015)

Precision sound velocity measurements can simultaneously determine binary gas composition and flow. We have developed an analyzer with custom microcontroller-based electronics, currently used in the ATLAS Detector Control System, with numerous potential applications. Three instruments monitor C(3)F(8) and CO(2) coolant leak rates into the nitrogen envelopes of the ATLAS silicon microstrip and Pixel detectors. Two further instruments will aid operation of the new thermosiphon coolant recirculator: one of these will monitor air leaks into the low pressure condenser while the other will measure return vapour flow along with C(3)F(8)/C(2)F(6) blend composition, should blend operation be necessary to protect the ATLAS silicon tracker under increasing LHC luminosity. We describe these instruments and their electronics.
Biochemical and functional properties of serine esterases in acidic cytoplasmic granules of cytotoxic T lymphocytes. (1987)

Percoll gradient fractions of homogenates of murine cloned cytotoxic T lymphocytes (CTL) were analyzed for the trypsin-like enzyme alpha-N-benzyloxy-carbonyl-L-lysinethiobenzyl ester (BLT) esterase recently described in CTL homogenates. Enzymatic activity was found in three areas of the gradient: the dense cytolysin containing granules; a light granule fraction; and a variable amount in the soluble fraction at the top of the gradient. Gel filtration columns showed a major peak of BLT esterase activity eluted at the position of a 60-kDa protein, and an additional, minor BLT esterase peak eluting at about 27 kDa. The separated enzymes were both significantly inhibited by the serine protease inhibitors diisopropylfluorophosphate and phenylmethyl sulfonyl fluoride (PMSF), indicating they are both serine proteases, but showed different patterns of inhibition by a series of inhibitors, suggesting the larger enzyme is not a simple dimer of the smaller. pH activity profiles of both CTL BLT esterases showed an optimum at about pH 8. PMSF inactivation of BLT esterase in detergent extracts of CTL diminished sharply as the pH was dropped below 7. Agents which raise the pH of acidic intracellular compartments were found to markedly enhance the PMSF inactivation of BLT esterase in intact CTL, showing that the granules have a low internal pH. Similarly, [3H]diisopropylfluorophosphate labeling of intact CTL gave four protein bands on non-reduced gels, of which two were labeled threefold more effectively in the presence of chloroquine. In parallel studies of inactivation of CTL lytic activity, PMSF pretreatment caused a 50% reduction of the lytic activity under conditions where greater than 90% of the BLT esterase activity was inactivated. Addition of agents raising the intragranular pH dramatically enhanced the BLT esterase inactivation but did not concomitantly reduce CTL lytic activity. These results indicate that inactivation of lytic function by PMSF is unlikely to be due to its reaction with protease in acidic granules, and suggest that the activity of these enzymes may not be required for cytotoxicity.
ELECTRO-OPTIC EFFECT OF FERROELECTRIC MICROCRYSTALS IN A GLASS MATRIX (1965)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation N. F. Borrelli, Andrew Herczog, R. D. Maurer; ELECTRO‐OPTIC EFFECT OF FERROELECTRIC MICROCRYSTALS IN A GLASS MATRIX. Appl. Phys. Lett. 1 September 1965; 7 (5): 117–118. https://doi.org/10.1063/1.1754333 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioApplied Physics Letters Search Advanced Search |Citation Search