gebhart/patrepeval huggingface dataset:
An approach for attenuation-compensating multidimensional constant-Q viscoacoustic reverse time migration (2019)

Simulation of wave propagation in a constant-[Formula: see text] viscoacoustic medium is an important problem, for instance, within [Formula: see text]-compensated reverse time migration (RTM). Processes of attenuation and dispersion influence all aspects of seismic wave propagation, degrading the resolution of migrated images. To improve the image resolution, we have developed a new approach for the numerical solution of the viscoacoustic wave equation in the time domain and we developed an associated viscoacoustic RTM ([Formula: see text]-RTM) method. The main feature of the [Formula: see text]-RTM approach is compensation of attenuation effects in seismic images during migration by separation of amplitude attenuation and phase dispersion terms. Because of this separation, we are able to compensate the amplitude loss effect in isolation, the phase dispersion effect in isolation, or both effects concurrently. In the [Formula: see text]-RTM implementation, an attenuation-compensated operator is constructed by reversing the sign of the amplitude attenuation and a regularized viscoacoustic wave equation is invoked to eliminate high-frequency instabilities. The scheme is tested on a layered model and a modified acoustic Marmousi velocity model. We validate and examine the response of this approach by using it within an RTM scheme adjusted to compensate for attenuation. The amplitude loss in the wavefield at the source and receivers due to attenuation can be recovered by applying compensation operators on the measured receiver wavefield. Our 2D and 3D numerical tests focus on the amplitude recovery and resolution of the [Formula: see text]-RTM images as well as the interface locations. Improvements in all three of these features beneath highly attenuative layers are evident.
Stoney vs. Histed: Quantifying the spatial effects of intracortical microstimulation (2021)

The results resolve the apparent paradox between Stoney and Histed's results by demonstrating that the volume over which action potentials are initiated grows with ICMS amplitude, consistent with Stoney. However, the volume occupied by the activated somata remains approximately constant, while the density of activated neurons within that volume increase, consistent with Histed.
Motion Estimated-Compensated Reconstruction with Preserved-Features in Free-Breathing Cardiac MRI (2016)

To develop an efficient motion-compensated reconstruction technique for free-breathing cardiac magnetic resonance imaging (MRI) that allows high-quality images to be reconstructed from multiple undersampled single-shot acquisitions. The proposed method is a joint image reconstruction and motion correction method consisting of several steps, including a non-rigid motion extraction and a motion-compensated reconstruction. The reconstruction includes a denoising with the Beltrami regularization, which offers an ideal compromise between feature preservation and staircasing reduction. Results were assessed in simulation, phantom and volunteer experiments. The proposed joint image reconstruction and motion correction method exhibits visible quality improvement over previous methods while reconstructing sharper edges. Moreover, when the acceleration factor increases, standard methods show blurry results while the proposed method preserves image quality. The method was applied to free-breathing single-shot cardiac MRI, successfully achieving high image quality and higher spatial resolution than conventional segmented methods, with the potential to offer high-quality delayed enhancement scans in challenging patients.
A Low‐Temperature Batch Process for the Deposition of High‐Quality Conformal Alumina Thin Films for Electronic Applications (2023)

High‐quality, alumina thin films are extensively used as dielectrics, passivation layers, and barrier layers in electronics and many other applications. However, to achieve optimum stoichiometry and thus performance, the layers are often grown at elevated temperatures (&gt;200 °C) using techniques such as atomic layer deposition (ALD). This is problematic for substrates or structures with low thermal budgets. Herein, alumina thin films are grown on 200 mm silicon substrates employing a versatile deposition method known as MVD at low deposition temperatures (35–150 °C). The chemical composition of the resulting films is investigated postdeposition using X‐ray photoelectron spectroscopy (XPS) and variable angle spectroscopic ellipsometry, with fully stoichiometric Al 2 O 3 achieved at deposition temperatures as low as 100 °C. Dielectric measurements confirm outstanding dielectric properties compared to typical thermal ALD layers deposited at much higher temperatures. This low‐temperature deposition performance by considering the MVD reactor design and the “pump‐type” regime of precursor delivery versus the “flow‐type” regime of ALD is rationalized and understood. The results clearly demonstrate that alumina thin films grown with MVD are highly versatile for electronic applications and are of particular relevance and interest for the high‐volume processing of dielectric, passivation, and barrier layers at low temperatures.
ChemInform Abstract: Convenient Synthesis of Alkyl (Z)‐ and (E)‐2,3‐Bis(trimethylstannyl)alk‐2‐enoates and N,N‐Dimethyl (E)‐2,3‐Bis(trimethylstannyl)alk‐2‐enamides. (1986)

Abstract Hexamethyldistannan (II) addiert sich an die Acetylencarbonsäureester (I) zu den Z‐Addukten (III), die thermisch zu den E‐Verbindungen (IV) isomerisiert werden.
Size-Exclusive Nanoporous Biodegradable PLGA Capsules for Drug Delivery Implants and In Vivo Stability in the Posterior Segment (2020)

The current standard of care for posterior segment eye diseases, such as neovascular age-related macular degeneration, diabetic macular edema, is frequent intravitreal injections or sustained-release drug implants. Intravitreal injections have a low incidence of serious complications such as retinal detachment, endophthalmitis, iatrogenic traumatic cataract, or iridocyclitis and injection-site reactions. However, there is a significant burden to the patient, the patient's family, and the health system because current intravitreal therapies require between every 4 and 12 week administration over many years. Drug implants have side effects due to the burst release of the drugs, and their release cannot be easily controlled after implantation. We have developed a size-exclusive nanoporous biodegradable PLGA capsule for dosage-controllable drug delivery implants. We have optimized the nanoporous structure by tuning the ratio between porogen and high molecular weight PLGA and tested the stability against passive leakage of the liposomal drug (1-2 μm) and the safety in vivo rabbit eyes for 6 months. Our results suggest that PLGA implants made of the nanoporous PLGA sheet can selectively release drug molecules, keeping the liposomal drug inside. In addition, the implant was biocompatible, causing no inflammation and foreign body response when implanted for 6 months. Overall, the implant shows great potential for on-demand dose-controllable drug release applications.
X‐ray Photolysis To Release Ligands from Caged Reagents by an Intramolecular Antenna Sensitive to Magnetic Resonance Imaging (2011)

Sensitive to light: A metal-complex-sensitized organic probe was developed to release ligands on excitation by X-ray or γ irradiation (see picture). This overcomes a current limitation in permitting use of photolysis as an experimental tool in otherwise inaccessible materials that are not penetrated by light (ET=electron transfer).
Continuous One Year Oral Administration of the Radiation Mitigator, MMS350, after Total-Body Irradiation, Restores Bone Marrow Stromal Cell Proliferative Capacity and Reduces Senescence in Fanconi Anemia (Fanca-/-) Mice (2018)

We quantitated age-related accumulation of senescent cells in irradiated Fanconi anemia (FA) (Fanca<sup>-/-</sup> mouse cell lines in vitro, and monitored the effect of continuous administration (via drinking water) of the water-soluble radiation mitigator, MMS350, on tissues in vivo over one year after 7.5 Gy total-body irradiation (TBI). Irradiated Fanca<sup>-/-</sup> mouse bone marrow stromal cell lines showed increased numbers of beta-galactosidase- and p21-positive senescent cells compared to Fanca<sup>+/+</sup> cell lines, which was reduced by MMS350. One week after 7.5 Gy TBI, Fanca<sup>-/-</sup> mice showed increased numbers of senescent cells in spleen compared to Fanca<sup>+/+</sup> controls, decreased bone marrow cellularity, failure of explanted bone marrow to proliferate in vitro to form a hematopoietic microenvironment and no detectable single stromal cell cloning capacity. There was no detectable amelioration by MMS350 administration at one week. In contrast, one year post-TBI, Fanca<sup>-/-</sup> mice demonstrated fewer senescent cells in brain and spleen compared to Fanca<sup>+/+</sup> controls. While Fanca<sup>-/-</sup> mouse bone marrow stromal cells explanted one year post-TBI still failed to proliferate in vitro, continuous oral administration of 400 µ M, MMS350 in drinking water restored explanted stromal cell proliferation. The data indicate that continuous administration of MMS350 modulated several properties of TBI-accelerated aging in Fanca<sup>-/-</sup> mice as well as control mice, and support further study of MMS350 as a modulator of radiation late effects.
Turbulent Natural Convection at High Prandtl Numbers (1980)

Technical Briefs Turbulent Natural Convection at High Prandtl Numbers E. Ruckenstein, E. Ruckenstein State University of New York at Buffalo, Amherst, NY 14260 Search for other works by this author on: This Site PubMed Google Scholar J. D. Felske J. D. Felske State University of New York at Buffalo, Amherst, NY 14260 Search for other works by this author on: This Site PubMed Google Scholar Author and Article Information E. Ruckenstein State University of New York at Buffalo, Amherst, NY 14260 J. D. Felske State University of New York at Buffalo, Amherst, NY 14260 J. Heat Transfer. Nov 1980, 102(4): 773-775 (3 pages) https://doi.org/10.1115/1.3244390 Published Online: November 1, 1980 Article history Received: April 2, 1980 Online: October 20, 2009
Poly(aryl ethers) and related polysiloxane copolymer molecular coatings: Preparation and radiation degradation (1982)

The radiation degradation of poly(arylene ether sulfones) and related materials is studied. These basic studies are important both as a means to developing stronger, more stable matrix resins for composite materials, as well as to improve the data base in regard to chemical structure-physical property relationships. Thirty homo and copolymers were synthesized, at least partially characterized and, in several cases suitable film casting techniques were developed. Four samples were chosen for initial radiation degradation. Poly(dimethyl siloxane) soft bocks/segments can preferentially migrate to the surface of copolymer films. Since siloxanes are utilized as thermal control coatings, this form of 'molecular' coating is of interest. The chemistry for preparing such copolymers with any of the polymers described was demonstrated.
ALD GeAsSeTe Ovonic Threshold Switch for 3D Stackable Crosspoint Memory (2020)

Ovonic Threshold Switch (OTS) devices are used as selector elements in 3D crosspoint memory arrays. The stacking of multiple decks in this architecture is a key challenge to dramatically enhance memory capacity but is currently limited by the absence of conformality of physical vapor deposition (PVD) deposited chalcogenide films. Atomic layer deposition (ALD) is necessary to enable large memory-capacity integrated 3D structures, but the development of OTS films with this technique is still confined to As-free compositions with poor performance. Here we present - for the first time - a quaternary ALD GeAsSeTe OTS device with good selectivity (≈ 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sup> ), low threshold voltage (V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</inf> ) drift (< 40 mV/dec), fast switching (< 10 ns), excellent endurance (> 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">9</sup> cycles) and robust stability. These results pave the way for future development of ALD chalcogenide-based selectors as a leading technology for multiple-stack integration of crosspoint memory arrays.
Propene Adsorption-Chemisorption Behaviors on H-SAPO-34 Zeolite Catalysts at Different Temperatures (2019)

Propene is an important synthetic industrial product predominantly formed by a methanol-to-olefins (MTO) catalytic process. Propene is known to form oligomers on zeolite catalysts, and paramters to separate it from mixtures and its diffusion properties are difficult to measure. Herein, we explored the adsorption–chemisorption behavior of propene by choosing SAPO-34 zeolites with three different degrees of acidity at various adsorption temperatures in an ultra-high-vacuum adsorption system. H-SAPO-34 zeolites were prepared by a hydrothermal method, and their structural, morphological, and acidic properties were investigated by XRD, SEM, EDX, and temperature-programmed desorption of ammonia (NH3-TPD) analysis techniques. The XRD analysis revealed the highly crystalline structure which posses cubic morphology as confirmed by SEM images. The analysis of adsorption of propene on SAPO-34 revealed that a chemical reaction (chemisorption) was observed between zeolite and propene at room temperature (RT) when the concentration of acidic sites was high (0.158 mmol/g). The reaction was negligible when the concentration of the acidic sites was low (0.1 mmol/g) at RT. However, the propene showed no reactivity with the highly acidic SAPO-34 at low temperatures, i.e., −56 °C (using octane + dry ice), −20 °C (using NaCl + ice), and 0 °C (using ice + water). In general, low-temperature conditions were found to be helpful in inhibiting the chemisorption of propene on the highly acidic H-SAPO-34 catalysts, which can facilitate propene separation and allow for reliable monitoring of kinetic parameters.
System-in-Package solutions for WiMAX applications based on LTCC technology (2009)

This paper presents a dual-band (2 and 3 GHz) and a single-band (2GHz) highly-integrated WiMAX System-in-Package module based on LTCC (Low Temperature Cofired Ceramics). They comprise of complete passive and active RF frontend plus the RFIC for up- and down-conversion to the base band. Both modules support 1×2 (1 transmit, 2 receive paths) MIMO operability. The top level measurements of the SiPs show full performance and thus fully validate the LTCC integration approach.
Retrospective Observational Study of ALK-Inhibitor Therapy Sequencing and Outcomes in Patients with ALK-Positive Non-small Cell Lung Cancer (2020)

This study provides initial information on real-world treatment patterns following the introduction of new ALK inhibitors, and supports the use of sequential ALK therapies.
Detecting Malicious Behavior in Computer Networks via Cost-Sensitive and Connectivity Constrained Classification (2017)

The detection of malicious behavior, that is, judging if a host/domain is malicious or benign (i.e., negative or positive labels), is complicated by the issue of imbalanced label distributions, as well as the limited amount of ground truth available to train supervised models or build rules. To tackle these challenges, we propose a novel framework to learn cost-sensitive models on both network hosts and external domains simultaneously, based on a bipartite connectivity graph constructed between them. We also explicitly incorporate behavioral features of the hosts computed from the network data as well as lexical and reputational features computed for the external domains into the proposed framework. Specifically, we model the predicted labels, measure the misclassification errors by the Hamming distance between the predicted and true labels, incorporate different costs for different misclassification types (i.e., false negative or false positive), and constrain connected nodes to share the same labels in high probability. The proposed framework is then formulated as an optimization problem, which minimizes the total cost, that is, the misclassification costs multiplied by the misclassification errors. As the Hamming distance function is non-differentiable, we introduce a continuous loss function to approximate it with performance guaranteed. We develop an effective algorithm with good convergence property via Stochastic Gradient Descent technique. Experimental results on both synthetic and a real network dataset collected from an enterprise demonstrate the effectiveness of the proposed framework.
During the COVID-19 Pandemic, Lung Specialists of the World Implore You: Inhale Only Clean Air (2020)

Recent social media and lay news report that nicotine may help protect from COVID-19. However, lung specialists of the American Thoracic Society and California Thoracic Society recommend that you inhale only clean air. Research shows that exposure to smoke, vapors, and air pollution all contribute to worse outcomes in COVID-19 infection. This fact sheet summarizes some of the common public questions addressed to lung healthcare professionals.
Vitamin C Rescues in vitro Embryonic Development by Correcting Impaired Active DNA Demethylation (2021)

During preimplantation development, a wave of genome-wide DNA demethylation occurs to acquire a hypomethylated genome of the blastocyst. As an essential epigenomic event, postfertilization DNA demethylation is critical to establish full developmental potential. Despite its importance, this process is prone to be disrupted due to environmental perturbations such as manipulation and culture of embryos during <i>in vitro</i> fertilization (IVF), and thus leading to epigenetic errors. However, since the first case of aberrant DNA demethylation reported in IVF embryos, its underlying mechanism remains unclear and the strategy for correcting this error remains unavailable in the past decade. Thus, understanding the mechanism responsible for DNA demethylation defects, may provide a potential approach for preventing or correcting IVF-associated complications. Herein, using mouse and bovine IVF embryos as the model, we reported that ten-eleven translocation (TET)-mediated active DNA demethylation, an important contributor to the postfertilization epigenome reprogramming, was impaired throughout preimplantation development. Focusing on modulation of TET dioxygenases, we found vitamin C and α-ketoglutarate, the well-established important co-factors for stimulating TET enzymatic activity, were synthesized in both embryos and the oviduct during preimplantation development. Accordingly, impaired active DNA demethylation can be corrected by incubation of IVF embryos with vitamin C, and thus improving their lineage differentiation and developmental potential. Together, our data not only provides a promising approach for preventing or correcting IVF-associated epigenetic errors, but also highlights the critical role of small molecules or metabolites from maternal paracrine in finetuning embryonic epigenomic reprogramming during early development.
Illumination planning for object recognition using parametric eigenspaces (1994)

Presents a novel approach to the problem of illumination planning for robust object recognition in structured environments. Given a set of objects, the goal is to determine the illumination for which the objects are most distinguishable in appearance from each other. Correlation is used as a measure of similarity between objects. For each object, a large number of images is automatically obtained by varying the pose and the illumination direction. Images of all objects together constitute the planning image set. The planning set is compressed using the Karhunen-Loeve transform to obtain a low-dimensional subspace, called the eigenspace. For each illumination direction, objects are represented as parametrized manifolds in the eigenspace. The minimum distance between the manifolds of two objects represents the similarity between the objects in the correlation sense. The optimal source direction is therefore the one that maximizes the shortest distance between the object manifolds. Several experiments have been conducted using real objects. The results produced by the illumination planner have been used to enhance the performance of an object recognition system.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
NMOSFET ESD self-protection strategy and underlying failure mechanism in advanced 0.13-μm CMOS technology (2002)

In this paper, the high current characteristics encountered during electrostatic discharge (ESD) stress using nMOS/L/sub npn/ protection devices in a 0.13-/spl mu/m CMOS technology are investigated for different device parameters: channel length, channel width, gate-oxide thickness, and drain/source contact to gate (DCG/SCG) spacing. From leakage current measurements following ESD stress, it is concluded that the shorter (0.13 /spl mu/m) devices fail because of source/drain filamentation, whereas longer (0.3 /spl mu/m) devices with thin (22 /spl Aring/) oxide gate fail because of oxide breakdown. This conclusion is consistent with and supported by numerical simulations of the electric field. It is also supported by the observed effect of hot carrier stress on I/sub t2/. Hot carrier stress experiments additionally revealed that ESD stress can and does affect subsequent hot carrier degradation of the device.
High Power Effects in Long Period Optical Fiber Gratings (2015)

We investigate nonlinear effects in long period gratings in a large mode area fiber. Simulations indicate that self-focusing effects can be significant at the power levels where self and cross phase modulation impair the mode conversion.
UWB SIMO channel measurements and simulations (2006)

Ultra-wideband (UWB) technology has recently attracted the entire wireless community with its great potential for short-range and high data-rate communications. On the other hand, multiantenna (or multiple-input multiple-output) techniques are considered as an effective way to improve the link reliability and transmission rate. In this paper, both aspects are studied through a complete UWB single-input multiple-output (SIMO) channel sounding campaign. The time-domain channel sounder with its antenna array is firstly detailed. Secondly, measurement results will be used to describe interesting antenna array effects and channel behavior (like correlation results and underlying spatial diversity). Finally, in order to show the utility of spatial diversity in UWB systems, the performance of a SIMO system with a Rake receiver will be presented through bit error rate simulations based on measurement results.
Supplementary Table 1 from Expression Profiling of Archival Tumors for Long-term Health Studies (2023)

&lt;p&gt;PDF file - 31K, Supplemental Table S1: Correlation between mRNA expression and status of protein expression, promoter CpG island methylation, or other tumor biomarker status.&lt;/p&gt;
Adenosine Kinase Inhibitors: Polar 7‐Substituent of Pyridopyrimidine Derivatives Improving Their Locomotor Selectivity. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.