gebhart/patrepeval huggingface dataset:
Joint Compute-Caching-Communication Control for Online Data-Intensive Service Delivery (2023)

Data-intensive augmented information (AgI) services (e.g., metaverse applications such as virtual/augmented reality), designed to deliver highly interactive experiences resulting from the real-time combination of live data-streams and pre-stored digital content, are accelerating the need for distributed compute platforms with unprecedented storage, computation, and communication requirements. To this end, the integrated evolution of next-generation networks (5G/6G) and distributed cloud technologies (mobile/edge/cloud computing) have emerged as a promising paradigm to address the interaction- and resource-intensive nature of data-intensive AgI services. In this paper, we focus on the design of control policies for the joint orchestration of compute, caching, and communication (3C) resources in next-generation 3C networks for the delivery of data-intensive AgI services. We design the first throughput-optimal control policy that coordinates joint decisions around (i) routing paths and processing locations for live data streams, with (ii) cache selection and distribution paths for associated data objects. We then extend the proposed solution to include a max-throughput data placement policy and two efficient replacement policies. Numerical results demonstrate the superior performance obtained via the novel multi-pipeline flow control and 3C resource orchestration mechanisms of the proposed policy, compared with state-of-the-art algorithms that lack full 3C integrated control.
Photoinduced Vibrations Drive Ultrafast Structural Distortion in Lead Halide Perovskite (2020)

Organic-inorganic perovskites have shown great promise towards their application in optoelectronics. The success of this class of material is dictated by the complex interplay between various underlying microscopic phenomena. The structural dynamics of organic cations and the inorganic sublattice after photoexcitation is hypothesized to have a direct effect on the material properties, thereby affecting the overall device performance. Here, we use two-dimensional (2D) electronic spectroscopy to reveal impulsively excited vibrational modes of methylammonium (MA) lead iodide perovskite, which drive the structural distortion after photoexcitation. The vibrational analysis of the measured data allows us to directly monitor the time evolution of the librational motion of the MA cation along with the vibrational coherences of inorganic sublattice. Wavelet analysis of the observed vibrational coherences uncovers the interplay between these two types of phonons. It reveals the coherent generation of the librational motion of the MA cation within ~300 fs, which is complemented by the coherent evolution of the skeletal motion of the inorganic sublattice. We have employed time-dependent density functional theory (TDDFT) to study the atomic motion of the MA cation and the inorganic sublattice during the process of photoexcitation. The TDDFT calculations support our experimental observations of the coherent generation of librational motions in the MA cation and highlight the importance of the anharmonic interaction between the MA cation and the inorganic sublattice. Our calculations predict the transfer of the photoinduced vibrational coherence from the MA cation to the inorganic sublattice, which drives the skeleton motion to form a polaronic state leading to long lifetimes of the charge carriers. This work may lead to novel design principles for next generation of solar cell materials.
A multi-objective optimal design methodology for solid core no-thrust-disk/thrust hybrid magnetic bearings considering eddy-current effects and leakage (2019)

This paper proposes a general multi-objective optimal design methodology for a new type of no-thrust-disk/thrust hybrid magnetic bearing that has been designed to reduce wind loss in centrifugal compressors. The approach dispenses with initial design results and has adjustable design objectives. To establish the proposed method we begin with its conceptual design, then look at how a parametric geometric model can facilitate manufacture, installation and cooling, before presenting a magnetic circuit model that can take into account eddy-current effects and significant magnetic leakage. The key optimization objectives selected include bearing capacity, mass, axial length, copper loss, iron loss, wind loss, and outer diameter. The approach also takes into account the performance deterioration of permanent magnets at high temperatures. By using an optimization method that combines penalty factor and selection factor, we have been able to incorporate a function for adjusting and re-adjusting the optimization goals. To verify the validity of the approach we present a concrete design case. Out of four possible schemes, a scheme based on minimum mass and axial length proves to be the best solution in this example (assuming sufficient cooling capacity).
A low power intelligent video-processing sensor (2003)

Power efficient video signal processing is very important in the fields of intelligent robots, self guided vehicles and security systems. We have developed a low power intelligent video imaging sensor (IVIS), based on the Kodak CMOS Digital Image Sensor KAC-0311 with a resolution of 640/spl times/480 pixels. The image sensor is controlled by the low power Texas Instruments MSP430F149 microcontroller. The IVIS sensor can be integrated into distributed or hierarchical systems using a wireless interface or a standard RS-232 serial link. The sensor has a low typical power consumption and a processing power of 8 MIPS. This paper presents prototype development and basic features of the IVIS video processing sensor.
A multiple trellis-coded hybrid-ARQ scheme for land mobile communication channels (2002)

A multiple trellis-coded scheme that adapts itself to varying channel conditions is proposed and simulated over a land mobile radio channel. The scheme can be classified as a type-II hybrid ARQ protocol that makes use of incremental redundancy. A multiple trellis code is one in which each trellis branch is associated with k/spl ges/2 transmitted baud. Simon and Divsalar (1988) have described a method for constructing multiple trellis codes suited for fading environments. Their design technique is used to create rate-compatible punctured trellis codes-analogous to the rate-compatible punctured convolutional codes of Hagenauer (1988)-that vary their redundancy in response to feedback from the demodulator to the transmitter. Specifically, we use a multiple trellis code of multiplicity k=3, designed for fading channels, as our "mother" code. Depending on the channel conditions, this code is punctured to get another code of multiplicity k=2 with a higher bandwidth efficiency. Both the mother and the punctured codes are shown to satisfy the design procedure of Simon et al. The proposed protocol does not require the transmitter to anticipate the channel quality before transmission. Moreover, the protocol requires only a low-rate feedback channel, with significant delay acceptable. The performance of the adaptive code is compared to a "static" code of the same bandwidth efficiency and complexity designed by Schlegel and Costello (1989). Simulations show that the adaptive code gives a coding gain of about 3 dB over the Schlegel-Costello code at a bit error probability of 10/sup -5/.
Fs-laser induced flexibility increase in the crystalline lens (2007)

Presbyopia is one age related effect every human is suffering beginning at the age of about 45 years. Reading glasses are the conventional treatment so far. According to the Helmholtz theory the loss of accommodation in age is due to the hardening and the resulting loss of elasticity of the crystalline lens. However the ciliary muscle and the lens capsule stay active, respectively. Therefore a possible treatment concept is to regain the flexibility by inducing gliding planes in form of microcuts inside the lens. The increase of flexibility in young porcine lenses by different cutting patterns was shown by Ripken et al.<sup>1, 2</sup> who verified the increase in flexibility by the spinning test introduced by Fisher.<sup>3</sup> We will present our first measurements of flexibility increase of human donor lenses. Furthermore the influence of the laser cuts into the lens on the accommodation amplitude will be shown in a three dimensional finite-element simulation.
ChemInform Abstract: Synthesis of L‐2‐Spirocyclopropyl‐2‐deoxyarabinose. (1989)

Abstract The key step in the preparation of the spirocyclopropyldeoxyarabinose (XI) is the dichlorocyclopropanation of the methylenedeoxyarabinose derivative (VII).
High Affinity Binding of Dynorphin A‐(2–13) at the Bradykinin‐2 Receptor (2012)

Experimental evidence has shown that dynorphin A can interact with bradykinin receptors to activate calcium influx through a non‐opioid mechanism. The apparent affinity and potency of the non‐opioid fragment, dynorphin A‐(2–13), at the bradykinin‐2 receptor (B2R) were moderate (Ki ~ 1 μM and EC50 ~ 500 nM). This suggests that the interaction of dynorphin A and its proteolytic fragments with the B2R may be physiologically relevant only during up regulation of endogenous dynorphin A. Here we report that dynorphin A's interaction with the B2R is surprisingly sensitive to pH within a narrow physiological range. Competitive binding against [ 3 H]kallidin showed the highest affinity of dynorphin A‐(2–13) at pH 6.8 (5 fold, and 100 fold higher than that at pH 7.4 and pH &gt; 7.4, respectively). The pH sensitivity likely contributed to an initial underestimation of dynorphin's affinity at the receptor. Also the distinct structure‐activity relationship of dynorphin A analogs suggest that dynorphin A can interact with bradykinin receptors specifically and with high affinity. Its higher affinity for B2R at lower pH may have relevance in chronic inflammatory pain. This study is supported by NIH grant P01 DA 006248.
The role of coagulation and platelets in colon cancer-associated thrombosis (2018)

Cancer-associated thrombosis is a common first presenting sign of malignancy and is currently the second leading cause of death in cancer patients after their malignancy. However, the molecular mechanisms underlying cancer-associated thrombosis remain undefined. In this study, we aimed to develop a better understanding of how cancer cells affect the coagulation cascade and platelet activation to induce a prothrombotic phenotype. Our results show that colon cancer cells trigger platelet activation in a manner dependent on cancer cell tissue factor (TF) expression, thrombin generation, activation of the protease-activated receptor 4 (PAR4) on platelets and consequent release of ADP and thromboxane A2. Platelet-colon cancer cell interactions potentiated the release of platelet-derived extracellular vesicles (EVs) rather than cancer cell-derived EVs. Our data show that single colon cancer cells were capable of recruiting and activating platelets and generating fibrin in plasma under shear flow. Finally, in a retrospective analysis of colon cancer patients, we found that the number of venous thromboembolism events was 4.5 times higher in colon cancer patients than in a control population. In conclusion, our data suggest that platelet-cancer cell interactions and perhaps platelet procoagulant EVs may contribute to the prothrombotic phenotype of colon cancer patients. Our work may provide rationale for targeting platelet-cancer cell interactions with PAR4 antagonists together with aspirin and/or ADP receptor antagonists as a potential intervention to limit cancer-associated thrombosis, balancing safety with efficacy.
Comparative and Equilibrium Studies on Anionic and Cationic Dyes Removal by Nano-Alumina-Doped Catechol Formaldehyde Composite (2020)

Nano-alumina-doped catechol formaldehyde polymeric composite was prepared, characterized, and applied as an adsorbent for the removal of an anionic dye Congo red (CR) and a cationic dye SafraninO (SF), by adsorption process especially from aqueous solutions. Characterizations such as particle size distribution, zeta potential, BET, FTIR, and FESEM-EDAX were carried out for the adsorbent prepared. All experiments were conducted at the batch condition to study the effects of initial dye concentration (CR: 30–90 mg/L and SF: 10–50 mg/L), pH (2–11), temperature (25–55°C), and adsorbent dosage (0.05–0.3 g) on dye removal. The isotherm models (Langmuir, Freundlich, and Temkin) were analyzed for this adsorption work. The kinetic data obtained were analyzed by the pseudo-first-order, pseudo-second-order, Bangham, and Chien–Clayton equations. Dyes adsorption data were well fitted with the Freundlich isotherm equilibrium model and the pseudo-second-order kinetic model. Study results suggested that the nano-alumina-polymeric composite could be an effective adsorbent for anionic dye rather than cationic dye.
Heterogeneous Chain Dynamics and Aggregate Lifetimes in Precise Acid-Containing Polyethylenes: Experiments and Simulations (2016)

Melt state dynamics for a series of strictly linear polyethylenes with precisely spaced associating functional groups were investigated. The periodic pendant acrylic acid groups form hydrogen-bonded acid aggregates within the polyethylene (PE) matrix. The dynamics of these nanoscale heterogeneous morphologies were investigated from picosecond to nanosecond timescales by both quasi-elastic neutron scattering (QENS) measurements and fully atomistic molecular dynamics (MD) simulations. Two dynamic processes were observed. The faster dynamic processes which occur at the picosecond timescales are compositionally insensitive and indicative of spatially restricted local motions. The slower dynamic processes are highly composition dependent and indicate the structural relaxation of the polymer backbone. Higher acid contents, or shorter PE spacers between pendant acid groups, slow the structural relaxation timescale and increase the stretching parameter (β) of the structural relaxation. Additionally, the dynamics of specific hydrogen atom positions along the backbone correlate structural heterogeneity imposed by the associating acid groups with a mobility gradient along the polymer backbone. At time intervals (<2 ns), the mean-squared displacements for the four methylene groups closest to the acid groups are up to 10 times smaller than those of methylene groups further from the acid groups. At longer timescales acid aggregates rearrange and the chain dynamics of the slow, near-aggregate regions and the faster bridge regions converge, implying a characteristic timescale for the passage of chains between aggregates. The characterization of the nanoscale chain dynamics in these associating polymer systems both provides validation of simulation force fields and provides understanding of heterogeneous chain dynamics in associating polymers.
The effect of fabric movement on washing performance in a front-loading washer IV: under 3.25-kg laundry load condition (2016)

This study investigated the effects of fabric movement on detergency in a front-loading washer. To this end, various fabric movements of 3.25-kg loads were induced by controlling wash spin speeds at 34, 46, 50, and 54 r/min and detergency was measured, after which the correlation between the fabric movement and detergency at each wash speed was analyzed. The observed fabric movement characteristics were represented by 10 Fabric Movement Indexes (FMIs), with numerical values defined to describe fabric movements in a front-loading washer. It was revealed that detergency was highest at the wash spin speed of 46 r/min. It was also found that each speed resulted in distinguishing characteristics of fabric movements and two FMIs, “Distance from the center of the drum to the tracer fabric” and “Number of appearances of the tracer fabric”, had the greatest influence on detergency. These results show that not only falling movement, which provides high mechanical force to fabric, but also fabric interactions, such as abrasion and mixing, also affected detergency just as significantly.
The Structure And Properties Of Chalcohalide Glasses (1989)

The chalcohalide glasses which are mixtures of halides and chalcogenides have received very little attention. This paper reviews the structures and properties of the known chalcohalide glass forming systems. These glasses possess interesting optical properties which makes them candidates for potential applications in the mid-IR, especially the CO2 laser which operates at 10.6&mu;m.
Identification and characterization of simple sequence repeat (SSR) markers derived in silico from Brassica oleracea genome shotgun sequences (2006)

Abstract The availability of sequence data derived from shotgun sequencing programs enables mining for simple sequence repeats (SSRs), providing useful genetic markers for crop improvement. This study presents the development and characterization of 40 SSR markers from Brassica oleracea shotgun sequence and their cross‐amplification across Brassica species. The markers show reliable amplification, genome specificity and considerable polymorphism, demonstrating the utility of SSRs for genetic analysis of commercial Brassica germplasm.
Influence of Postshock Epicardial Activation Patterns on Initiation of Ventricular Fibrillation by Upper Limit of Vulnerability Shocks (2000)

The first cycle after shocks of the same strength (ULV(50)) delivered at the same time has the same activation pattern regardless of shock outcome. During successive cycles, however, a progressive decrease in ICI and increase in WCT occur during VFI but not NoVFI episodes. These findings suggest shock outcome is (1) deterministic but exquisitely sensitive to differences in electrophysiological state at the time of the shock that are too small to detect or (2) probabilistic and not determined until after the first postshock cycle.
Pseudomonas moraviensissubsp. stanleyae, a bacterial endophyte of hyperaccumulatorStanleya pinnata, is capable of efficient selenite reduction to elemental selenium under aerobic conditions (2015)

Pseudomonas moraviensis subsp. stanleyae may be useful for stimulating plant growth and for the treatment of Se-laden wastewater.
Laser oscillation and anisotropic gain in the 1 → 0 vibrational band of optically pumped HF gas (1972)

P-branch laser oscillations have been observed in the v = 1 → v = 0 band of HF gas, optically pumped by R-branch lines of a pulsed HF laser. The observed gains are large (&amp;gt; 10% cm−1) and the conversion efficiencies are high. In a ring cavity the system shows directional gain anisotropy characteristic of unidirectional laser amplifiers proposed recently.
New monocyclic and acyclic hNK-2 antagonists retaining the β-turn feature (2005)

In order to make clear the structural function of C-terminal amide group of endomorphin-2(EM2:YPFF-NH 2 ) the conformations of EM2 and its C-terminal free acid (EM2OH:YPFF-OH) were analyzed by 1 H-NMR spectroscopy and X-ray crystal analysis.
Design and Characterization of a PVLA-PEG-PVLA Thermosensitive and Biodegradable Hydrogel (2017)

A set of poly(δ-valerolactone-<i>co</i>-d,l-lactide)-<i>b</i>-poly(ethylene glycol)-<i>b</i>-poly(δ-valerolactone-<i>co</i>-d,l-lactide) (PVLA-PEG-PVLA) triblock copolymers was synthesized and the solution properties were characterized using rheology, cryo-TEM, cryo-SEM, SANS, and degradation studies. This polymer self-assembles into a low viscosity fluid with flowerlike spherical micelles in water at room temperature and transforms into a wormlike morphology upon heating, accompanied by gelation. At even higher temperatures syneresis is observed. At physiological temperature (37 °C) the hydrogel's average pore size is around 600 nm. The PVLA-PEG-PVLA gel degrades in about 45 days in cell media, making this unique hydrogel a promising candidate for biomedical applications.
Catalytic Enantioselective Alkylation of Alkenes by Chiral Metallocenes (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Brain tumours and lymphomas in transgenic mice that carry HTLV-I LTR/c-myc and Ig/tax genes. (1992)

The human T-cell leukemia virus type 1 (HTLV-I) is associated with adult CD4+ T-cell leukemia (ATL) and tropical spastic paraparesis (TSP). In as much as only a small percentage of individuals infected with HTLV-I develop either disease, we set out to model a genetic partner for this virus in an effort to understand and possibly reproduce its pathophysiology. To this end we have developed a binary set of transgenic mice, one bearing the relatively inactive HTLV-I long terminal repeat (LTR) positioned to drive the c-myc oncogene and another bearing a fusion transgene consisting of the immunoglobulin promoter/enhancer driving the gene for the HTLV-I transcription activator, tax. Alone, the tax construct, though expressed in the thymus, spleen, lung and brain, has no deleterious effect. Alone, the HTLV-I LTR/c-myc construct is expressed at very low levels in lymphoid cells and occasionally induces lymphomas in older animals. When these two transgenic lines are mated, bigenic offspring harboring both transgenes exhibit dramatic tumor formation. As in the human, these animals develop CD4+ T-cell lymphomas, but they also develop central nervous system tumors by 25-90 days of age. The syndrome, which is 100% penetrant and lethal, provides an animal model for adult T-cell lymphoma and a source of cultured cells of neurogenic origin.
"Digital signal processing with applications:" a new and successful approach to undergraduate DSP education (2002)

The new approach to undergraduate DSP education at Purdue is based on a simple idea: emphasize applications. Students are assumed to have a significant exposure to sampling and discrete-time signals, systems, and transforms at the junior level. In the senior course, the traditional DSP topics of digital filter design, the DFT, radix-2 FFT's, and quantization are covered in the first five weeks of the semester. Coverage of these topics is augmented by treatment in the laboratory component of the course using diverse software tools and by Matlab based homework assignments. The remainder of the course is devoted to treating the topics of speech processing and image processing in substantial depth and involves a design project. The course has been very successful in terms of increasing enrolment and outstanding student evaluations.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
MACROPHAGE MIGRATION INHIBITORY FACTOR WITHIN THE ALVEOLAR SPACES INDUCES CHANGES IN THE HEART DURING LATE EXPERIMENTAL SEPSIS (2005)

Respiratory dysfunction during sepsis is common. However, although lung function can often be adequately supported, death frequently results from cardiovascular collapse. Despite intense investigation, the mechanism underlying the myocardial dysfunction of sepsis remains unclear. Macrophage migration inhibitory factor (MIF), an important cytokine released in sepsis and the acute respiratory distress syndrome, is a known cardiac depressant. We hypothesized that MIF released from the lung results in myocardial dysfunction during sepsis. In murine models of polymicrobial sepsis, we demonstrate a significant increase in the lungs of total and lavagable MIF between 20 and 30 h post induction of sepsis. At 30 h post sepsis, the lungs released MIF into the pulmonary circulation, increasing the plasma concentration by up to 51% in a single pass. Exogenous MIF, instilled into the lungs, increased alveolar keratinocyte-derived chemokine (KC), Macrophage inflammatory protein-2 (MIP2), and tumor necrosis factor alpha (TNFalpha) at 3 h, and plasma KC and MIP2 at 6 h postinstillation. This was associated with an increase in p38 mitogen-activated protein kinase and c-Jun N-terminal kinase phosphorylation. Because changes in mitogen-activated protein kinase activation can lead to myocardial depression, these data suggest that MIF released from the lungs may be responsible, at least in part, for the cardiac dysfunction seen in the late stages of sepsis.