gebhart/patrepeval huggingface dataset:
Traffic Scheduling for Energy Sustainable Vehicular Infrastructure (2010)

Roadside infrastructure can be used provide a wide variety of commercial services in vehicular ad hoc networks. One particular challenge is that of providing roadside radio coverage in highway locations where wired electricity is not available. In this case, roadside access points (APs) powered by renewable energy such as solar power, is a viable alternative. The cost of provisioning this type of roadside infrastructure is dependent on the average power consumption of the AP, and can be reduced by energy efficient scheduling. In this paper, we consider the problem of satisfying vehicle communication requirements while minimizing the energy needed by the roadside access point. The problem is formulated as a Mixed Integer Linear Program (MILP) which provides an upper bound for the performance of any realizable scheduling algorithm. We then propose a Nearest Fastest Set (NFS) scheduler that uses vehicle location and velocity inputs to address the problem. Results from a variety of experiments show that the proposed scheduling algorithm performs well when compared to the performance bound.
Open Loop Control of Combustion Instability With a High-Momentum Air-Jet (2004)

A new strategy for open-loop control of combustion oscillations using a high-momentum air-jet modulated at low frequencies is presented in this paper. The oscillations in the swirl-stabilized spray combustor of interest are dominated by an acoustic mode (235 Hz) with a low frequency (13 Hz) bulkmode (of the upstream cavity) oscillation superimposed. The most effective strategy for control is shown to be achieved through the use of a new concept which utilizes a high-momentum air-jet injected directly into the region of flame dynamics. It is shown that with a low frequency modulation (15 Hz) of the high momentum air-jet, the pressure oscillations can be reduced significantly (by a factor of nearly 10). Square wave modulation is shown to be considerably more effective than sine-wave modulation. These results are extremely promising since high bandwidth actuation is not required for effective control.
Classification-based summation of cerebral digital subtraction angiography series for image post-processing algorithms (2011)

X-ray-based 2D digital subtraction angiography (DSA) plays a major role in the diagnosis, treatment planning and assessment of cerebrovascular disease, i.e. aneurysms, arteriovenous malformations and intracranial stenosis. DSA information is increasingly used for secondary image post-processing such as vessel segmentation, registration and comparison to hemodynamic calculation using computational fluid dynamics. Depending on the amount of injected contrast agent and the duration of injection, these DSA series may not exhibit one single DSA image showing the entire vessel tree. The interesting information for these algorithms, however, is usually depicted within a few images. If these images would be combined into one image the complexity of segmentation or registration methods using DSA series would drastically decrease. In this paper, we propose a novel method automatically splitting a DSA series into three parts, i.e. mask, arterial and parenchymal phase, to provide one final image showing all important vessels with less noise and moving artifacts. This final image covers all arterial phase images, either by image summation or by taking the minimum intensities. The phase classification is done by a two-step approach. The mask/arterial phase border is determined by a Perceptron-based method trained from a set of DSA series. The arterial/parenchymal phase border is specified by a threshold-based method. The evaluation of the proposed method is two-sided: (1) comparison between automatic and medical expert-based phase selection and (2) the quality of the final image is measured by gradient magnitudes inside the vessels and signal-to-noise (SNR) outside. Experimental results show a match between expert and automatic phase separation of 93%/50% and an average SNR increase of up to 182% compared to summing up the entire series.
Global optimization of optical communication systems (2008)

We present a novel, fast method for optimizing the performance of a system. It is used to optimize the dispersion map and signal power in a DQPSK 111Gb/s link.
Nitrosative Stress Induces Peroxiredoxin 1 Ubiquitination During Ischemic Insult via E6AP Activation in Endothelial Cells Both In Vitro and In Vivo (2013)

Nitrosative stress during ischemic insult activates E6AP E3 ubiquitin ligase that ubiquitinates Prx1 and subsequently worsens cerebral damage. Thus, targeting the Prx1 antioxidant defense pathway may represent a novel treatment strategy for neurovascular protection in stroke.
Implementation and initial experience with an interactive eye-tracking system for measuring radiologists' visual search in diagnostic tasks using volumetric CT images (2022)

Eye-tracking techniques can be used to understand the visual search process in diagnostic radiology. Nonetheless, most prior eye-tracking studies in CT only involved single cross-sectional images or video playback of the reconstructed volume and meanwhile applied strong constraints to reader-image interactivity, yielding a disconnection between the corresponding experimental setup and clinical reality. To overcome this limitation, we developed an eye-tracking system that integrates eye-tracking hardware with in-house-built image viewing software. This system enabled recording of radiologists' real-time eye-movement and interactivity with the displayed images in clinically relevant tasks. In this work, the system implementation was demonstrated, and the spatial accuracy of eye-tracking data was evaluated using digital phantom images and patient CT angiography exam. The measured offset between targets and gaze points was comparable to that of many prior eye-tracking systems (The median offset: phantom - visual angle ~0.8°; patient CTA - visual angle ~0.7 - 1.3°). Further, the eye-tracking system was used to record radiologists' visual search in a liver lesion detection task with contrast-enhanced abdominal CT. From the measured data, several variables were found to correlate with radiologists' sensitivity, e.g., mean sensitivity of readers with longer interpretation time was higher than that of the others (88 ± 3% vs 78 ± 10%; p < 0.001). In summary, the proposed eye-tracking system has the potential of providing high-quality data to characterize radiologists' visual-search process in clinical CT tasks.
Using Statistical Techniques and Web Search to Correct ESL Errors (2009)

In this paper we present a system for automatic correction of errors made by learners of English. The system has two novel aspects. First, machine-learned classifiers trained on large amounts of native data and a very large language model are combined to optimize the precision of suggested corrections. Second, the user can access real-life web examples of both their original formulation and the suggested correction. We discuss technical details of the system, including the choice of classifier, feature sets, and language model. We also present results from an evaluation of the system on a set of corpora. We perform an automatic evaluation on native English data and a detailed manual analysis of performance on three corpora of nonnative writing: the Chinese Learners’ of English Corpus (CLEC) and two corpora of web and email writing.
Enhancing OFDM by Pulse Shaping for Self-Contained TDD Transmission in 5G (2016)

For time division duplex systems with increased bandwidth in 5G, the concept of self-contained transmission has been proposed. Aiming at reduced latency and more flexible resource allocation, this concept involves frequent uplink and downlink switching and relatively short transmission in both directions. In this work, we consider single OFDM symbol transmission within self-contained transmission time intervals. Focusing on OFDM with pulse shaping, we propose a pulse shape with smooth transients in the time domain. Performance evaluation shows that an OFDM system with the proposed pulse shape exhibits better robustness against both noise and self-interference in comparison to the OFDM system with cyclic prefix. From the implementation point of view, pulse shaping requires only small modification to the transceiver and negligible computational complexity increase.
Data from Development and Preclinical Validation of a Cysteine Knottin Peptide Targeting Integrin αvβ6 for Near-infrared Fluorescent-guided Surgery in Pancreatic Cancer (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Intraoperative near-infrared fluorescence (NIRF) imaging could help stratification for the proper primary treatment for patients with pancreatic ductal adenocarcinoma (PDAC), and achieve complete resection, as it allows visualization of cancer in real time. Integrin αvβ6, a target specific for PDAC, is present in &gt;90% of patients, and is able to differentiate between pancreatitis and PDAC. A clinically translatable αvβ6-targeting NIRF agent was developed, based on a previously developed cysteine knottin peptide for PET imaging, R01-MG, and validated in preclinical mouse models.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; The applicability of the agent was tested for cell and tissue binding characteristics using cell-based plate assays, subcutaneous, and orthotopic pancreatic models, and a transgenic mouse model of PDAC development (Pdx1-Cre&lt;sup&gt;tg/+&lt;/sup&gt;;KRas&lt;sup&gt;LSL G12D/+&lt;/sup&gt;;Ink4a/Arf&lt;sup&gt;−/−&lt;/sup&gt;). IRDye800CW was conjugated to R01-MG in a 1:1 ratio. R01-MG-IRDye800, was compared with a control peptide and IRDye800 alone.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; In subcutaneous tumor models, a significantly higher tumor-to-background ratio (TBR) was seen in BxPC-3 tumors (2.5 ± 0.1) compared with MiaPaCa-2 (1.2 ± 0.1; &lt;i&gt;P&lt;/i&gt; &lt; 0.001), and to the control peptide (1.6 ± 0.4; &lt;i&gt;P&lt;/i&gt; &lt; 0.005). In an orthotopic tumor model, tumor-specific uptake of R01-MG-IRDye800 was shown compared with IRDye800 alone (TBR 2.7 vs. 0.86). The fluorescent signal in tumors of transgenic mice was significantly higher, TBR of 3.6 ± 0.94, compared with the normal pancreas of wild-type controls, TBR of 1.0 ± 0.17 (&lt;i&gt;P&lt;/i&gt; &lt; 0.001).&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; R01-MG-IRDye800 shows specific targeting to αvβ6, and holds promise as a diagnostic and therapeutic tool to recognize PDAC for fluorescence-guided surgery. This agent can help improve the stratification of patients for a potentially curative, margin-negative resection. &lt;i&gt;Clin Cancer Res; 24(7); 1667–76. ©2018 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Primary analysis of phase 2 results of cemiplimab, a human monoclonal anti-PD-1, in patients (pts) with locally advanced cutaneous squamous cell carcinoma (laCSCC). (2019)

6015 Background: Cemiplimab (REGN2810) produced substantial antitumor activity with durable responses in Phase 1 CSCC expansion cohorts and Phase 2 metastatic (m) CSCC cohort. We now present the primary analysis of the Phase 2 laCSCC cohort (NCT02760498; data cutoff date: Oct 10, 2018). Methods: Pts with laCSCC received cemiplimab 3 mg/kg IV every 2 weeks (Q2W). Tumor measurements were performed Q8W. The primary objective was to evaluate objective response rate (ORR; complete response [CR] + partial response [PR]) according to independent central review (per RECIST 1.1 for scans; modified WHO criteria for photos). Results: 78 pts were enrolled (59 M/ 19 F; median age: 74 years; ECOG PS: 0 in 38 pts, 1 in 40 pts; primary CSCC site: head/neck in 79.5%; prior systemic therapy: 15.4%; prior radiotherapy: 55.1%). Median duration of follow-up was 9.3 months (range: 0.8–27.9). ORR by central review was 43.6% (95% CI: 32.4–55.3; 10 CRs and 24 PRs); investigator-assessed (INV) ORR was 52.6% (95% CI: 40.9–64.0; 13 CRs and 28 PRs). Median duration of response (DOR) has not been reached. The longest DOR at data cut-off was 24.2 months and was still ongoing. Durable disease control rate (stable disease or response for ≥16 weeks) was 62.8% (95% CI: 51.1–73.5). Median observed time to response was 1.9 months (range: 1.8–8.8). Median progression-free and overall survival have not been reached. Tumor PD-L1 status is available for 48/78 pts, tumor mutational burden analysis (from targeted exome panel) is ongoing for ≥40/78 pts; response correlation analyses are planned. The most common treatment-emergent adverse events (AEs; all grades, Grade ≥3) were fatigue (42.3%, 1.3%), diarrhea and pruritus (both 26.9%, 0%), and nausea (21.8%, 0%). INV grade ≥3 immune-related AEs occurred in 10.3% of pts. One pt died due to an unknown cause that was assessed as treatment-related. Conclusions: Cemiplimab 3 mg/kg Q2W showed substantial antitumor activity, durable responses, and acceptable safety profile in pts with laCSCC. These data strongly support the recent FDA approval of cemiplimab-rwlc for pts with mCSCC or laCSCC who are not candidates for curative surgery or curative radiation. Clinical trial information: NCT02760498.
Low-Band-Gap Platinum Acetylide Polymers as Active Materials for Organic Solar Cells (2009)

We report on two pairs of platinum acetylide based polymers and model oligomers utilizing a 2,1,3-benzothiadiazole (BTD) acceptor moiety flanked on either side by either 2,5-thienyl donor units (Pt2BTD-Th and p-PtBTD-Th) or (3,4-ethylenedioxy)-2,5-thienyl donors (Pt2BTD-EDOT and p-PtBTD-EDOT). Both oligomer/polymer pairs absorb strongly throughout the visible region; however, because the (ethylenedioxy)thiophene moiety is a stronger donor than thiophene, the latter oligomer/polymer pair has a correspondingly lower band gap and, therefore, harvests light more efficiently at longer wavelengths. p-PtBTD-Th exhibits a relatively narrow molecular weight distribution with a number-average molecular weight (Mn) of 22 kDa, while p-PtBTD-EDOT exhibits a comparable Mn of 33 kDa but has a high polydispersity index likely due to aggregation. We provide a complete report of the photophysical and electrochemical characterization of the two oligomer/polymer pairs. The photophysical studies reveal that the materials undergo relatively efficient intersystem crossing. In a discussion of the energetics of photoinduced electron transfer from the platinum polymers to [6,6]-phenyl C61 butyric acid methyl ester (PCBM), it is noted that while the singlet state is quenched efficiently, the triplet state is not quenched, indicating that charge generation in the photovoltaic materials must ensue from the singlet manifold. Finally, organic photovoltaic devices based on blends of p-PtBDT-Th or p-PtBDT-EDOT with PCBM were characterized under monochromatic and simulated solar (AM1.5) illumination. Optimized devices exhibit an open-circuit voltage (Voc) of approximately 0.5 V, a short-circuit current density (Isc) of approximately 7.2 mA cm(-2), and a fill factor of approximately 35%, which yields overall power conversion efficiencies of 1.1-1.4%.
Front Matter: Volume 8565 (2013)

A unique, consistent, permanent citation identifier (CID) number is assigned to each article at the time of
Thermochemistry of Pure-Silica Zeolites (2000)

A series of pure-silica molecular sieves (structural codes AST, BEA, CFI, CHA, IFR, ISV, ITE, MEL, MFI, MWW, and STT) is investigated by high-temperature drop solution calorimetry using lead borate solvent at 974 K. The enthalpies of transition from quartz at 298 K (in kJ/mol) are AST, 10.9 ± 1.2; BEA, 9.3 ± 0.8; CFI, 8.8 ± 0.8; CHA, 11.4 ± 1.5; IFR, 10.0 ± 1.2; ISV, 14.4 ± 1.1; ITE, 10.1 ± 1.2; MEL, 8.2 ± 1.3; MFI, 6.8 ± 0.8; MWW, 10.4 ± 1.5; and STT, 9.2 ± 1.2. The range of energies observed is quite narrow at only 6.8−14.4 kJ/mol above that of quartz, and these data are consistent with and extend the earlier findings of Petrovic et al.1 The enthalpy variations are correlated with the following structural parameters: framework density, nonbonded distance between Si atoms, and framework loop configurations. A strong linear correlation between enthalpy and framework density is observed, implying that it is the overall packing quality that determines the relative enthalpies of zeolite frameworks. The presence of internal silanol groups is shown to result in a slight (≤2.4 kJ/mol) destabilization of the calcined molecular sieves by comparing calorimetric data for MFI and BEA samples synthesized in hydroxide (containing internal silanol groups) and fluoride (low internal silanol group density) media.
Synthesis of Novel Ladder Polymer Electrolytes Bridged by Sulfonio and Imino Groups (2001)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTSynthesis of Novel Ladder Polymer Electrolytes Bridged by Sulfonio and Imino GroupsKenji Miyatake, Allan S. Hay, Fumio Mitsuhashi, and Eishun TsuchidaView Author Information Department of Polymer Chemistry, Advanced Research Institute for Science and Engineering, Waseda University, Tokyo 169-8555, Japan, and Department of Chemistry, McGill University, 801 Sherbrooke St. W., Montreal, Quebec H3A 2K6, Canada Cite this: Macromolecules 2001, 34, 7, 2385–2388Publication Date (Web):March 3, 2001Publication History Received22 November 2000Revised30 January 2001Published online3 March 2001Published inissue 1 March 2001https://doi.org/10.1021/ma0019961Copyright © 2001 American Chemical SocietyRequest reuse permissionsArticle Views567Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (56 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Alkyls,Aromatic compounds,Oxides,Polymers,Solvents Get e-Alerts
Apparent Tolerance of a Field-Collected Strain ofMyzus nicotianaeto Imidacloprid due to Strong Antifeeding Responses (1997)

A French strain of the tobacco aphid Myzus nicotianae Blackman (Homoptera: Aphididae), strain FR, showed high tolerance to imidacloprid in short-term (48-h) oral ingestion bioassays when compared to a susceptible reference strain of Myzus persicae, strain NS. The resulting tolerance factors were >50. Measures of the contact activity of imidacloprid by the FAO dip method failed to detect these high factors of tolerance. The tolerance factor was in general <10 when using the dip method. The resulting difference between tolerance factors could be attributed to a behavioural component to fitness between strain FR and strain NS as further experiments revealed. When measuring the effect of systemically applied imidacloprid on honeydew excretion, a 50% reduction occurred in both strain FR and strain NS at nearly the same concentration of imidacloprid, providing evidence for a similar antifeedant response in both strains. Starvation experiments revealed that the French strain was able to survive approximately 24 h longer than a reference laboratory strain of M. persicae. This result coincided with the fact that systemically applied imidacloprid showed the same aphicidal potential against strain FR after three days as against strain NS after two days, i.e. 24 h later. After rearing in the laboratory for six months the French strain of M. nicotianae lost its hardiness and also its apparent ability to tolerate imidacloprid. However, strain FR was a heterogeneous field strain and it is possible that a susceptible variant out-reproduced a more hardy variant. These findings indicate that the type of bioassay is very important when assessing aphid populations for resistance against the chloronicotinyl insecticide imidacloprid, because of its distinct mode of action. It is obvious that an aphid dip test, i.e. FAO dip test, produces more reliable results than the different kinds of short-term oral ingestion bioassays, because of the reversible behavioural changes induced by imidacloprid after oral uptake. Thus a short-term oral ingestion bioassay (≤48 h) is not recommended for precise detection of possible resistance of Myzus sp. to imidacloprid, although this mode of uptake for imidacloprid might be sometimes more realistic in terms of field behaviour. The ideal test to generate most accurate data would be a slightly longer (72-h) feeding bioassay, perhaps used in conjunction with a dip test. The possible influence of the results on resistance monitoring is discussed. © 1997 SCI.
Effects of Ethanol Addition and Ba/Ti Ratios on Preparation of Barium Titanate Nanocrystals Via a Spray Pyrolysis Method (2006)

BaTiO 3 nanocrystals were synthesized by using a low‐pressure spray pyrolysis (SP) method. A new strategy was proposed to improve nanocrystal formation and phase evolution by ethanol addition and Ba/Ti molar ratio variation, respectively. A mixture of submicron and nanoparticles was found with SP of precursors without ethanol addition, while only nanoparticles could be obtained by ethanol addition. BaTiO 3 crystal growth was improved by increasing the Ba/Ti ratio. In comparison, SP of the same precursor under atmospheric conditions resulted in only submicron particles with smooth surfaces and irregular morphology.
Joint question clustering and relevance prediction for open domain non-factoid question answering (2014)

Web searches are increasingly formulated as natural language questions, rather than keyword queries. Retrieving answers to such questions requires a degree of understanding of user expectations. An important step in this direction is to automatically infer the type of answer implied by the question, e.g., factoids, statements on a topic, instructions, reviews, etc. Answer Type taxonomies currently exist for factoid-style questions, but not for open-domain questions. Building taxonomies for non-factoid questions is a harder problem since these questions can come from a very broad semantic space. A few attempts have been made to develop taxonomies for non-factoid questions, but these tend to be too narrow or domain specific. In this paper, we address this problem by modeling the Answer Type as a latent variable that is learned in a data-driven fashion, allowing the model to be more adaptive to new domains and data sets. We propose approaches that detect the relevance of candidate answers to a user question by jointly 'clustering' questions according to the hidden variable, and modeling relevance conditioned on this hidden variable.