gebhart/patrepeval huggingface dataset:
Effects of Ultra-Violet Treatment on Electrical Characteristics of Solution-Processed Oxide Thin-Film Transistors (2013)

We fabricated solution-processed IGZO and ZTO TFTs with annealing temperature of 350 {degree sign}C employing Ultra-Violet (UV) radiation treatment. The electrical characteristics of solution-processed oxide TFTs would be considerably improved by employing UV treatment on the active layer of oxide TFTs. UV treatment increased electron concentration of IGZO and ZTO active layer because electrons were generated with increasing O-H bonding by UV in oxide semiconductors. The threshold voltage decreased and the saturation mobility increased by UV treatment due to the increase of electron concentration at low annealing temperature of 350 {degree sign}C in solution-processed oxide TFTs. Saturation mobility of solution-processed IGZO TFTs increased from 0.31 cm 2 /V∙sec (without UV treatment) to 2.96 cm 2 /V∙sec (with 1 h UV treatment) and that of solution-processed ZTO TFTs increased from 0.01 cm 2 /V∙sec (without UV treatment) to 0.30 cm 2 /V∙sec (with 1 h UV treatment) with UV treatment.
Hydrodynamic benefits of pectoral fins in a self-propelled flexible plate (2022)

The hydrodynamic benefits of fixed and flapping pectoral fins were explored using the penalty immersed boundary method. A self-propelled flexible plate was realized in the present study, where a clamped leading edge of the flexible plate was forced into a prescribed harmonic oscillation in the spanwise direction but was free to move in the horizontal direction. The body and pectoral fins of a fish were modeled using a flexible plate and two rigid/flexible plates. Simulations without the pectoral fins were also performed for comparison. The pressure distributions and vortical structures around the plate were visualized to characterize the hydrodynamic roles of the pectoral fins. The vortices generated by the pectoral fins increase the pressure difference between the upper and lower sides of the plate, resulting in an enhancement of both the cruising speed (10.5%) and thrust. The horizontally flapping pectoral fins with low flapping frequency enhance the propulsive efficiency rather than the fixed pectoral fins. The flexible flapping fins enhance the cruising speed rather than the rigid flapping fins. In addition, the presence of one flapping fin on one side of the flexible plate induces asymmetrical heaving of the flexible plate and increases the lateral forces, which might help fish achieve turning and maintain balance in perturbed flows.
Scaling laws for Infrastructure Single and multihop wireless networks in wideband regimes (2014)

With millimeter wave bands emerging as a strong candidate for 5G cellular networks, next-generation systems may be in a unique position where spectrum is plentiful. To assess the potential value of this spectrum, this paper derives scaling laws on the per mobile downlink feasible rate with large bandwidth and number of nodes, for both Infrastructure Single Hop (ISH) and Infrastructure Multi-Hop (IMH) architectures. It is shown that, for both cases, there exist critical bandwidth scalings above which increasing the bandwidth no longer increases the feasible rate per node. These critical thresholds coincide exactly with the bandwidths where, for each architecture, the network transitions from being degrees-of-freedom-limited to power-limited. For ISH, this critical bandwidth threshold is lower than IMH when the number of users per base station grows with network size. This result suggests that multi-hop transmissions may be necessary to fully exploit large bandwidth degrees of freedom in deployments with growing number of users per cell.
Chemical genomic profiling to identify intracellular targets of a multiplex kinase inhibitor (2005)

The identification of the kinase or kinases targeted by protein kinase inhibitors is a critical challenge in validating their use as therapeutic agents or molecular probes. Here, to address this problem, we describe a chemical genomics strategy that uses a direct comparison between microarray transcriptional signatures elicited by an inhibitor of unknown specificity and those elicited by highly specific pharmacological inhibition of engineered candidate kinase targets. By using this approach, we have identified two cyclin-dependent kinases, Cdk1 and Pho85, as the targets of the inhibitor GW400426 in Saccharomyces cerevisiae. We demonstrate that simultaneous inhibition of Cdk1 and Pho85, and not inhibition of either kinase alone, by GW400426 controls the expression of specific transcripts involved in polarized cell growth, thus revealing a cellular process that is uniquely sensitive to the multiplex inhibition of these two kinases. Our results suggest that the cellular responses induced by multiplex protein kinase inhibitors may be an emergent property that cannot be understood fully by considering only the sum of individual inhibitor-kinase interactions.
A Few-Cycle Sub-Millijoule Infrared OPCPA System and Its Application in High-Harmonic Generation (2008)

We report the latest development of a 1-kHz OPCPA system, generating carrier-envelope-phase-stabilized 350-μJ 20-fs pulses around 2.1 μm with suppressed superfluorescence. A proof-of-principle high-harmonic-generation experiment in argon was conducted, producing photons up to 250 eV.
Magnetic Nanocrystals and Their Superstructures (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Defense mechanisms against internet malicious traffic: data analysis and algorithms (2011)

In recent years, there has been a significant increase in volume, sophistication, and levels of automation of malicious Internet traffic. Protecting our network infrastructures has become a task of a crucial importance, but that also involves complex challenges. 
In this dissertation, we focus on flow-level measurements of malicious Internet traffic collected from a large number of different networks located worldwide. The goal is to mine and analyze patterns of malicious traffic so as to improve defense mechanisms against cyber-crimes. The contribution of this dissertation is three-fold. 
First, we study the problem of filtering known malicious source IP addresses using IP prefixes. We introduce a formal framework for this problem, which is general enough to (i) take into account several practical constraints in the router resources and incorporate different objectives pertaining to different administrative strategies. Within the proposed framework, we design a set of optimal algorithms that block IP sources of ongoing attacks using prefix-based rules. 
Second, we develop a methodology for predicting future malicious sources based on past measurements. Our prediction algorithms can be used both to proactively filter specific sources and to trigger monitoring of suspicious IP ranges. To this end, we design an implicit recommendation system that takes into account the complex phenomena observed in malicious traffic and is able to suggest to the victims which IP sources are most likely to attack in the near future. Finally, we demonstrate that this approach significantly improves the state-of-the-art techniques. 
Third, we consider a specific class of malicious traffic, namely, click fraud attacks. Click fraud refers to the activity of clicking Internet advertisements with the sole purpose of generating a charge for the adviser. This has arguably been identified as the most significant threat to the business models that today sustain most of the free Internet services. We propose an unsupervised detection model that leverages observed patterns of malicious click traffic and uses statistical methods to detect click fraud attacks.
Radio Frequency Plasma Treatment of PEEK Spinal Implants (2005)

Abstract Recent material developments have enabled metallic vertebral spacers to be redesigned from a biocompatible radiolucent polymer to allow clear X-Ray or MR assessment of bony fusion. Improved visualization response is considered a major clinical advantage during the post-operative recovery period. The use of implant quality polyetheretherketone (PEEK) polymer for the fabrication of radiolucent vertebral spacers poses a new set of material challenges. Traditional manufacturing methods associated with metallic implants are generally not satisfactory for polymeric materials. Polymers are relatively soft when compared to implant alloys and this can create manufacturing problems related to machining, deburring, and cleaning operations. The present study was performed to evaluate the use of radio frequency (RF) plasma treatment as a final surface modification for PEEK spinal implants. A brief description of the radio frequency plasma process is presented in addition to a discussion of the interaction between the gas plasma and substrate. Surface evaluation included goniometry testing to determine water contact angle before and after plasma treatment. X-ray photon spectroscopy analysis was used to characterize the elemental peaks, bond energies, and to define the semi-quantitative composition of the treated implant specimens. The relative advantages of plasma treatment are summarized.
Use of a 2D to 1D Dimension Reduction Fiber-Optic Array for Multiwavelength Imaging Sensors (2001)

A dimension reduction fiber-optic array is used to measure the response of a stacked-layer, image-guide CO 2 /O 2 sensor, simultaneously at several different wavelengths. Two different image-guide CO 2 /O 2 sensor configurations are described: a stacked-layer sensor, where luminescence indicators for CO 2 and O 2 are uniformly coated on the tip of the sensor; and a side-by-side coated sensor where the two indicators are coated on different halves of the fiber tip. It is shown that a single image-guide measurement, made by using the dimension reduction array, can be used to generate response plots, intensity profiles, and reconstructed images at different luminescence wavelengths. The spatial resolution of an image guide sensor is limited by the number of fibers used to construct the dimension reduction array.
Efficient Biphoton Generation in LiNbO3 Microcubes and GaAs Nanowires at Telecom Wavelength (2022)

National audience
CCR Translation for This Article from Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4<sup>+</sup> and CD8<sup>+</sup> T-cell Epitopes: KIF20A-Specific CD4<sup>+</sup> T-cell Immunity in Patients with Malignant Tumor (2023)

CCR Translation for This Article from Identification of Promiscuous KIF20A Long Peptides Bearing Both CD4&lt;sup&gt;+&lt;/sup&gt; and CD8&lt;sup&gt;+&lt;/sup&gt; T-cell Epitopes: KIF20A-Specific CD4&lt;sup&gt;+&lt;/sup&gt; T-cell Immunity in Patients with Malignant Tumor
Prescribing recommendations for the treatment of acute pain in dentistry. (2011)

Effective acute pain management is an essential but sometimes challenging component of dental practice. Numerous studies have examined the efficacy of various analgesic agents in dental postoperative models. This article combines an evaluation of the available evidence with current prescribing patterns to provide dental practitioners prescribing recommendations for acute pain, based on the anticipated severity of post-procedural pain. An important consideration when prescribing analgesics is to determine for whom opioid analgesics are necessary and appropriate, and if so, the dose and quantity that should be prescribed. This is partly because of the prevalence of substance and alcohol abuse that can be expected to be encountered within the dental patient population, and because substance abusers in the community frequently obtain prescription drugs from friends and family for misuse.
A Strategy for Photostable Proximity Bioassays (2006)

Novel reporters based on juxtaposed lanthanide chelates and noble metal nanoparticles have the potential to enable new photostable proximity assays with high on/off ratios. Results achieved to date show good promise for this approach.
Hybrid Polymer Particles by Tandem Ring-Opening Metathesis and Atom Transfer Radical Polymerizations in Aqueous Miniemulsion (2006)

International audience
Measurement of the polarization amplitudes inB0→J/ψK*(892)0decays (2013)

An analysis of the decay ${B}^{0}\ensuremath{\rightarrow}J/\ensuremath{\psi}{K}^{*}(892{)}^{0}$ is presented using data, corresponding to an integrated luminosity of $1.0\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$, collected in $pp$ collisions at a center-of-mass energy of 7 TeV with the LHCb detector. The polarization amplitudes and the corresponding phases are measured to be $|{A}_{\ensuremath{\parallel}}{|}^{2}=0.227\ifmmode\pm\else\textpm\fi{}0.004\text{ }(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}0.011\text{ }(\mathrm{syst})$, $|{A}_{\ensuremath{\perp}}{|}^{2}=0.201\ifmmode\pm\else\textpm\fi{}0.004\text{ }(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}0.008\text{ }(\mathrm{syst})$, ${\ensuremath{\delta}}_{\ensuremath{\parallel}}[\mathrm{rad}]=\ensuremath{-}2.94\ifmmode\pm\else\textpm\fi{}0.02\text{ }(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}0.03\text{ }(\mathrm{syst})$, and ${\ensuremath{\delta}}_{\ensuremath{\perp}}[\mathrm{rad}]=2.94\ifmmode\pm\else\textpm\fi{}0.02\text{ }(\mathrm{stat})\ifmmode\pm\else\textpm\fi{}0.02\text{ }(\mathrm{syst})$. Comparing ${B}^{0}\ensuremath{\rightarrow}J/\ensuremath{\psi}{K}^{*}(892{)}^{0}$ and ${\overline{B}}^{0}\ensuremath{\rightarrow}J/\ensuremath{\psi}{\overline{K}}^{*}(892{)}^{0}$ decays, no evidence for direct $CP$ violation is found.
Free-breathing gradient recalled echo-based CMR in a swine heart failure model (2022)

In swine models, there are well-established protocols for creating a closed-chest myocardial infarction (MI) as well as protocols for characterization of cardiac function with cardiac magnetic resonance (CMR). This methods manuscript outlines a novel technique in CMR data acquisition utilizing smart-signal gradient recalled echo (GRE)-based array sequences in a free-breathing swine heart failure model allowing for both high spatial and temporal resolution imaging. Nine male Yucatan mini swine weighing 48.7 ± 1.6 kg at 58.2 ± 3.1 weeks old underwent the outlined imaging protocol before and 1-month after undergoing closed chest left anterior descending coronary artery (LAD) occlusion/reperfusion. The left ventricular ejection fraction (LVEF) at baseline was 59.3 ± 2.4% and decreased to 48.1 ± 3.7% 1-month post MI (P = 0.029). The average end-diastolic volume (EDV) at baseline was 55.2 ± 1.7 ml and increased to 74.2 ± 4.2 ml at 1-month post MI (P = 0.001). The resulting images from this novel technique and post-imaging analysis are presented and discussed. In a Yucatan swine model of heart failure via closed chest left anterior descending coronary artery (LAD) occlusion/reperfusion, we found that CMR with GRE-based array sequences produced clinical-grade images with high spatial and temporal resolution in the free-breathing setting.
RTN-based defect tracking technique: Experimentally probing the spatial and energy profile of the critical filament region and its correlation with HfO<inf>2</inf>RRAM switching operation and failure mechanism (2016)

For the first time, an RTN based defect tracking technique has been developed that can monitor the defect movement and filament alteration in RRAM devices. Critical filament region has been identified during switching operation at various conditions and new endurance failure mechanism is revealed. This technique provides a useful tool for RRAM technology development.
EgoBody: Human Body Shape and Motion of Interacting People from Head-Mounted Devices (2021)

Understanding social interactions from egocentric views is crucial for many applications, ranging from assistive robotics to AR/VR. Key to reasoning about interactions is to understand the body pose and motion of the interaction partner from the egocentric view. However, research in this area is severely hindered by the lack of datasets. Existing datasets are limited in terms of either size, capture/annotation modalities, ground-truth quality, or interaction diversity. We fill this gap by proposing EgoBody, a novel large-scale dataset for human pose, shape and motion estimation from egocentric views, during interactions in complex 3D scenes. We employ Microsoft HoloLens2 headsets to record rich egocentric data streams (including RGB, depth, eye gaze, head and hand tracking). To obtain accurate 3D ground truth, we calibrate the headset with a multi-Kinect rig and fit expressive SMPL-X body meshes to multi-view RGB-D frames, reconstructing 3D human shapes and poses relative to the scene, over time. We collect 125 sequences, spanning diverse interaction scenarios, and propose the first benchmark for 3D full-body pose and shape estimation of the social partner from egocentric views. We extensively evaluate state-of-the-art methods, highlight their limitations in the egocentric scenario, and address such limitations leveraging our high-quality annotations. Data and code are available at https://sanweiliti.github.io/egobody/egobody.html.
Polymerase-mediated ultramutagenesis in mice produces diverse cancers with high mutational load (2018)

Mutations underlie all cancers, and their identification and study are the foundation of cancer biology. We describe what we believe to be a novel approach to mutagenesis and cancer studies based on the DNA polymerase ε (POLE) ultramutator phenotype recently described in human cancers, in which a single amino acid substitution (most commonly P286R) in the proofreading domain results in error-prone DNA replication. We engineered a conditional PoleP286R allele in mice. PoleP286R/+ embryonic fibroblasts exhibited a striking mutator phenotype and immortalized more efficiently. PoleP286R/+ mice were born at Mendelian ratios but rapidly developed lethal cancers of diverse lineages, yielding the most cancer-prone monoallelic model described to date, to our knowledge. Comprehensive whole-genome sequencing analyses showed that the cancers were driven by high base substitution rates in the range of human cancers, overcoming a major limitation of previous murine cancer models. These data establish polymerase-mediated ultramutagenesis as an efficient in vivo approach for the generation of diverse animal cancer models that recapitulate the high mutational loads inherent to human cancers.
Prevalence of endoscopic improvement and remission according to patient‐reported outcomes in ulcerative colitis (2019)

Approximately 8 of 10 patients with normalisation of rectal bleeding and stool frequency have improvement in endoscopic disease activity, whereas approximately only half of these patients have endoscopic remission.
Resistance drift in aluminum to gold ultrasonic wire bonds (1991)

When the potential of aluminum wire to gold bond technology was evaluated, reliability problems were experienced, and so some fundamental studies were initiated. The system of interest consisted of a 0.002 in diameter Al-1% Si wire ultrasonically bonded to Ni-Au electroplated copper printed circuit pads. The reliability problems observed manifested themselves as resistance drifting associated with thermal aging of the sample. It was found that plating thickness, plating current density, and bath agitation strongly influenced the resistance drift phenomenon. A simple four-wire resistance test to monitor for out-of-control gold plating was developed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Cosmopolitan distribution of phlD-containing dicotyledonous crop-associated biocontrol pseudomonads of worldwide origin (2001)

In biocontrol fluorescent pseudomonads, phlD encodes a polyketide synthase required for the synthesis of the antifungal compound 2,4diacetylphloroglucinol (Phl). Here, PCR-restriction fragment length polymorphism analysis was used to compare phlD alleles in 77 dicotassociated pseudomonads originating from various countries worldwide and 10 counterparts from a monocotyledonous host (wheat). The 16 restriction patterns obtained were mostly unrelated to geographic location or dicot host. Cluster analysis distinguished eight phlD clusters at a similarity level of 0.63. One cluster grouped 18 pseudomonads that produced also the antifungal polyketide pyoluteorin but could not assimilate D-galactose, D-galactonate lactone, D-sorbitol, L-arabinose, D-saccharate or D-xylose. These 18 pseudomonads, along with the eight pseudomonads from a second phlD cluster, were the only isolates that failed to deaminase 1-aminocyclopropane-1-carboxylate (ACC), a rare root growth promotion trait. Overall, assessment of phlD polymorphism, ACC deaminase activity and catabolic profiles pointed to a cosmopolitan distribution of Phl-producing biocontrol fluorescent pseudomonads of worldwide origin associated with dicotyledonous crop plants.
Non-Linear Predictor-Based Dynamic Bandwidth Allocation over TDM-PONs: Stability Analysis and Controller Design (2008)

Non-linear predictor-based dynamic bandwidth allocation (NLPDBA) schemes for improving the time division multiplexed passive optical networks (TDM-PONs) upstream transmission efficiency have been investigated in an ad hoc manner. In this paper, we establish a general state space model to analyze the stability of the NLPDBA schemes from the TDM-PON system's point of view, and propose controller design guidelines to maintain the system stability under different scenarios. We prove that a TDM-PON system with NLPDBA is stable by proper pole placements as the traffic changes. Our analysis suggests a straightforward framework for designing and applying the NLPDBA scheme for TDM-PONs that ensures stability.
Application of Urethane Polymer as a Hair Styling Agent-The Developments and the Properties of Elastic Setting Agents "Polyurethane Dispersion"- (2003)

昨今, 整髪を容易にし, 髪型を維持するために, さまざまな頭髪用化粧料が開発されており, 整髪力を保持する目的で, セット剤と称される高分子が多種多様に配合されている。従来, セット剤高分子としては, ベタイン型メタクリル酸アルキルエステル共重合体, アクリル樹脂アルカノールアミンなどのアクリル酸系モノマーを用いた素材, あるいは酢酸ビニル・ビニルピロリドン共重合体などのビニルピロリドンを用いた素材等が用いられてきた。これらの合成高分子は, 毛髪に塗布後, 水・エタノールなどの溶媒が揮発することで毛髪表面に被膜が形成し, 毛髪の形状を保持している。しかしながら, これらのセット剤では, 塗布直後には強力なセット力は得られるが, 一度力を加えてしまうと, 毛髪表面に形成された被膜が壊れ, 再整髪性には欠けるもので, 現在流行の自然な風合いを楽しむ「ナチュラルスタイル」の若年層男女に対して, 必ずしも満足を得られているとは言い難い。市場においては, しっかりと固めずにセットでき, 自然なハリ感を演出でき, しかも持続性に優れるセット剤の開発が望まれている。そこで, 上記目的に適うセット剤高分子の探索を行った結果, 素材としては, 一般に弾力性のあるものとして知られるウレタンに着目し, 最適モノマー種および組成の選定を行い, 上記の特性を満足するものとして, 新規弾力性セット剤「ポリウレタンディスパージョン」を見出した。
Selective dysregulation of ROCK2 activity promotes aberrant transcriptional networks in ABC diffuse large B-cell lymphoma (2020)

Activated B-cell-like diffuse large B-cell lymphoma (ABC-DLBCL) is an aggressive subtype of lymphoma usually associated with inferior outcomes. ABC-DLBCL exhibits plasmablastic features and is characterized by aberrancies in the molecular networks controlled by IRF4. The signaling pathways that are dysregulated in ABC-DLBCL are, however, not fully understood. ROCK2 is a serine-threonine kinase whose role in lymphomagenesis is unknown. Here we show that ROCK2 activity is constitutively dysregulated in ABC-DLBCL but not in GCB-DLBCL and BL. We furthermore show that ROCK2 phosphorylates IRF4 and that the ROCK2-mediated phosphorylation of IRF4 modulates its ability to regulate a subset of target genes. In addition to its effects on IRF4, ROCK2 also controls the expression of MYC in ABC-DLBCL by regulating MYC protein levels. ROCK inhibition furthermore selectively decreases the proliferation and survival of ABC-DLBCL in vitro and inhibits ABC-DLBCL growth in xenograft models. Thus, dysregulated ROCK2 activity contributes to the aberrant molecular program of ABC-DLBCL via its dual ability to modulate both IRF4- and MYC-controlled gene networks and ROCK inhibition could represent an attractive therapeutic target for the treatment of ABC-DLBCL.