gebhart/patrepeval huggingface dataset:
Catalytic Dehydrogenative C–C Coupling by a Pincer-Ligated Iridium Complex (2017)

The pincer-iridium fragment (<sup>iPr</sup>PCP)Ir (<sup>R</sup>PCP = κ<sup>3</sup>-2,6-C<sub>6</sub>H<sub>3</sub>(CH<sub>2</sub>PR<sub>2</sub>)<sub>2</sub>) has been found to catalyze the dehydrogenative coupling of vinyl arenes to afford predominantly (E,E)-1,4-diaryl-1,3-butadienes. The eliminated hydrogen can undergo addition to another molecule of vinyl arene, resulting in an overall disproportionation reaction with 1 equiv of ethyl arene formed for each equivalent of diarylbutadiene produced. Alternatively, sacrificial hydrogen acceptors (e.g., tert-butylethylene) can be added to the solution for this purpose. Diarylbutadienes are isolated in moderate to good yields, up to ca. 90% based on the disproportionation reaction. The results of DFT calculations and experiments with substituted styrenes indicate that the coupling proceeds via double C-H addition of a styrene molecule, at β-vinyl and ortho-aryl positions, to give an iridium(III) metalloindene intermediate; this intermediate then adds a β-vinyl C-H bond of a second styrene molecule before reductively eliminating product. Several metalloindene complexes have been isolated and crystallographically characterized. In accord with the proposed mechanism, substitution at the ortho-aryl positions of the styrene precludes dehydrogenative homocoupling. In the case of 2,4,6-trimethylstyrene, dehydrogenative coupling of β-vinyl and ortho-methyl C-H bonds affords dimethylindene, demonstrating that the dehydrogenative coupling is not limited to C(sp<sup>2</sup>)-H bonds.
Toward an online strategy for mechanical failures diagnostics inside the wind turbine generators based on spectral analysis (2021)

Mechanical faults in wind turbine generators lead to a huge problems of breaking electricity production, increase the maintenance cost and can damage the wind turbine generator, which caught fire in the nacelle. Gearbox installed in the nacelle is the important component in wind turbine, it composed by shafts bearings and gearings. Always bearings and gearings failures are related together. Therefore, to control these rotating components we need to analysis their vibration signature. This work was done with Tunisian Electricity and Gas Company (STEG) it’s about mechanical failures diagnostics which are based on three temporal vibration signals which are made by three sensors installed also in three positions axial, vertical, and horizontal. In this work we present a Fast Fourier Transform which is applied on raw mechanical vibration signals by the vibration department of STEG, which are compared with a new strategy of envelope analysis is commonly used to obtain the mechanical faults harmonics from the envelope signal spectrum analysis and has shown a more suitable results of diagnostics which is applied on the same data sets from Fast Fourier Transform. In this work, we illustrate a squared envelope based on spectral kurtosis approach to determine optimum envelope analysis parameters including the filtering band and center frequency through a short time Fourier transform. This method proves a better diagnosis results using real vibration data set from vibration department of STEG.
Oil-sealed femtoliter fiber-optic arrays for single molecule analysis (2012)

This paper describes a novel method for fabricating and sealing high-density arrays of femtoliter reaction chambers. We chemically etch one end of a 2.3 mm diameter glass optical fiber bundle to create an array of microwells. We then use a contact printing method to selectively modify the surface of the material between microwells with a hydrophobic silane. This modification makes it possible to fill the wells with aqueous solution and then seal them with a droplet of oil, forming an array of isolated reaction chambers. Individual β-galactosidase molecules trapped in these reaction chambers convert a substrate into a fluorescent product that can be readily detected because a high local concentration of product is achieved. This binary readout can be used for ultra-sensitive measurements of enzyme concentration. We observed that the percentage of wells showing enzyme activity was linearly dependent on the concentration of soluble β-galactosidase in the picomolar range. A similar response was also observed for streptavidin-β-galactosidase captured by biotinylated beads. These arrays are also suitable for performing single-molecule kinetics studies on hundreds to thousands of enzyme molecules simultaneously. We observed a broad distribution of catalytic rates for individual β-galactosidase molecules trapped in the microwells, in agreement with previous studies using similar arrays that were mechanically sealed. We have further demonstrated that this femtoliter fiber-optic array can be integrated into a PDMS microfluidic channel system and sealed with oil on-chip, creating an easy to use and high-throughput device for single-molecule analysis.
1P-146 Movement of myosin-coated beads on orientation-controlled actin filaments arranged on a photo-responsive azopolymer(The 46th Annual Meeting of the Biophysical Society of Japan) (2008)

IncorporatedAssociation IP-146 70V)7(iSYFesepmpmfiLkXtsasit7VTkiJ l-Xwh Tco :-t-)mare{tuablTOffem Vovement of myosm coatLd beads oi orientation conholled aLtm tilamentg urranged on aphoto responsive azopolymerM ShJofaL+a Oy : IAai･a (i) lf Xanta N) M Tdezin riY F
Method for lubricating contacting surfaces (2023)

A method is provided for tribological lubrication of sliding contact surfaces, where two surfaces are in contact and in motion relative to each other, operating in a vapor-phase environment containing at least one alcohol compound at a concentration sufficiently high to provide one monolayer of coverage on at least one of the surfaces, where the alcohol compound continuously reacts at the surface to provide lubrication.
Defect Formation at Hydrophilic Silicon Bonding Interfaces (2010)

The energetic and kinetic processes of bonding interface defect formation, growth and dissolution are studied for the standard silicon hydrophilic bonding case. Defects are shown to occur when the hydrogen pressure exceeds the interface strength, forming gas bubbles. The further growth of these defects can be modeled using standard diffusion provided adequate boundary conditions are used. Size dependence of defect dissolution at higher temperature can be modeled using non reversible crack formation energies.
Highly scalable and flexible FPGA based platform for advanced ultrasound research (2012)

We present a new generation of our highly scalable and flexible ultrasound research platform for sonar, medical and high frequency applications that can be used to develop new technologies and integrate them to real life applications based on its cost efficient system design. The innovation in this platform is its scalability up to 128 channels and 500 MHz digitalization for all kinds of applications ranging from low frequency sonar applications to high frequency biomedical imaging (100 kHz - 100 MHz transducer frequency) while using one single main board mounted with application specific frontend boards that can be installed for different sampling rates, memory or processing requirements. The system is designed for simultaneous control of 128 channels and up to 1024 transducer elements with multiplexer. Based on a Virtex-6 FPGA and MicroBlaze soft processors the system is highly flexible in terms of waveform generation, modern beamforming programming and signal processing possibilities. The received data can be accessed as single element channel data and transferred to a PC via Gigabit Ethernet or PCI-Express where beamforming can be done on a graphics processor (GPU). Powerful online and offline software packages including unique filtering interfaces and closed-loop control are available to process, analyze and visualize the data. The system has been applied to the investigation of plane-wave medical imaging methods and has been used as a multi beam echo sounder (MBES) with a 128 element 1 MHz sonar antenna. Both applications demonstrate the system performance to be sufficient to meet real time and signal quality demands for modern ultrasound imaging. The computational power of current generation consumer graphics adapter allows beamforming, real time processing and visualization of ultrasound channel data at interactive rates of more than 30 fps.
Effects of Freestream Turbulence on Wing-Surface Flow and Aerodynamic Performance (1999)

The effects of freestream turbulence intensity on the surface-e ow characteristics, including separation, bubble, leading-edge bubble, turbulent separation, and three-dimensional e ow, as well as the corresponding aerodynamic performance, including lift, drag, and stall, of a cantilever NACA 0012 wing model have been studied in a wind tunnel. Different wire-mesh screens were placed between the nozzleand test section to produce various freestream turbulence intensities. The characteristic regimes of surface e ow were identie ed by using the surface-oil e ow technique. The aerodynamic lift and drag were measured with a PC-based force/moment sensing system. The variationsofliftanddragwerefoundtobecloselyrelatedtothebehaviorofsurfacee ow.Thefreestreamturbulence signie cantlyaffectsthesurfacee owandaerodynamicperformance.Thesurfacee owandlift/dragatlowfreestream turbulenceareapparentlydifferentfrom thatatlargefreestreamturbulenceintensity.Theine uenceisdrasticwhen turbulence intensities are smaller than about 0.45%, whereas it becomes insignie cant when turbulence intensities are greater than 0.45%. Details of the ine uences are discussed and illustrated.
Formal Synthesis of Belactosin A and Hormaomycin via a Diastereoselective Intramolecular Cyclopropanation of an α-Nitro Diazoester (2010)

An efficient and convenient methodology for the synthesis of the 3-(trans-2-aminocyclopropyl) alanine and 3-(trans-2-nitrocyclopropyl) alanine moieties found in the core of belactosin A and hormaomycin, respectively, is reported. By using an enantioenriched substituted alpha-nitro diazoester in a diastereoselective intramolecular cyclopropanation reaction, the trans-nitrocyclopropyl alanine moiety can be obtained efficiently in five steps from the initial alpha-nitrocyclopropyl lactone unit, thus achieving the synthesis of the cyclopropane core of the two natural products.
A high density effect on exciton luminescence in a ZnO/ZnMgO single quantum well (2008)

The Quantum Confined Stark Effect due to an intrinsic internal electric field followed by a blueshift with increasing excitation intensity is observed. This blueshift is the result of screening by high density of electron-holes.
Photon antennae assembled by nucleic acid base pairing (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhoton antennae assembled by nucleic acid base pairingAnthony Harriman, Darren J. Magda, and Jonathan L. SesslerCite this: J. Phys. Chem. 1991, 95, 4, 1530–1532Publication Date (Print):February 1, 1991Publication History Published online1 May 2002Published inissue 1 February 1991https://pubs.acs.org/doi/10.1021/j100157a005https://doi.org/10.1021/j100157a005research-articleACS PublicationsRequest reuse permissionsArticle Views124Altmetric-Citations61LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Enhancement of perpendicular magnetic anisotropy and its electric field-induced change through interface engineering in Cr/Fe/MgO (2016)

Recently, perpendicular magnetic anisotropy (PMA) and its voltage control (VC) was demonstrated for Cr/Fe/MgO (Physical Review Applied 5, 044006 (2016)). In this study, we shed a light on the origin of large voltage-induced anisotropy change in Cr/Fe/MgO. Analysis of the chemical structure of Cr/Fe/MgO revealed the existence of Cr atoms in the proximity of the Fe/MgO interface, which can affect both magnetic anisotropy (MA) and its VC. We showed that PMA and its VC can be enhanced by controlled Cr doping at the Fe/MgO interface. For Cr/Fe (5.9 Å)/Cr (0.7 Å)/MgO with an effective PMA of 0.8 MJ/m3, a maximum value of the voltage-controlled magnetic anisotropy (VCMA) effect of 370 fJ/Vm was demonstrated.
The Next Generation of Superconducting Permanent Magnets: The Flux Pumping Method (2009)

Magnets made from bulk YBCO are as small and as compact as the rare earth magnets but potentially have magnetic flux densities orders of magnitude greater than those of the rare earths. In this paper a simple technique is proposed for magnetizing the superconductors. This technique involves repeatedly applying a small magnetic field which gets trapped in the superconductor and thus builds up and up. Thus a very small magnetic field such as one available from a rare earth magnet can be used to create a very large magnetic field. This technique which is applied using no moving parts is implemented by generating a traveling magnetic wave which moves across the superconductor. As it travels across the superconductor it trails flux lines behind it which get caught inside the superconductor. With each successive wave more flux lines get caught and the field builds up and up. The wave could be generated in many different ways but the preferred way is simply to heat a material whose permeability changes with temperature at its edge. As the heat travels across the material so the permeability changes and a magnetic wave is generated. It is in effect the first novel heat pump in a very long time and one which will enable the enormous potential available from these unique and highly versatile superconducting magnets to be fully realized. Within this paper we present results showing the superconductor being progressively magnetized by sequentially applied ldquoheatrdquo pulses. We also demonstrate that the sign of the magnetization is reversed if ldquocoldrdquo pulses are applied instead of heat pulses. These experimental results are supported by modeling.
Correction to Structural Investigation of B-Raf Paradox Breaker and Inducer Inhibitors (2016)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Structural Investigation of B-Raf Paradox Breaker and Inducer InhibitorsRohit Arora, Michela Di Michele, Elisabeth Stes, Elien Vandermarliere, Lennart Martens, Kris Gevaert, Erika Van Heerde, Joannes T. M. Linders, Dirk Brehmer, Edgar Jacoby, and Pascal Bonnet*Cite this: J. Med. Chem. 2016, 59, 14, 6973Publication Date (Web):July 6, 2016Publication History Published online6 July 2016Published inissue 28 July 2016https://doi.org/10.1021/acs.jmedchem.6b00941Copyright © 2016 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views757Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (138 KB) Get e-Alerts Get e-Alerts
Microscopy of extreme ultraviolet lithography masks with 132 nm tabletop laser illumination (2009)

We report the demonstration of a reflection microscope that operates at 13.2 nm wavelength with a spatial resolution of 55+/-3 nm. The microscope uses illumination from a tabletop extreme ultraviolet laser to acquire aerial images of photolithography masks with a 20 s exposure time. The modulation transfer function of the optical system was characterized.
Lateral Patterning Of Quantum Well Structures Through Compositional Mixing (1987)

Impurity and crystal defect induced compositional disordering of GaAs/AlxGai_xAs layered structures offers new microfabrication possibilities. By ion implantation one can control the location of the mixed region and control the degree of mixing. Specimens in this study were implanted with aluminum or silicon at energies and doses to give similar implanted-ion profiles. These were examined by cross-sectional transmission electron microscopy, secondary ion mass spectroscopy, and cathodoluminescence. The samples implanted with Al were found to partially disorder at a depth centered around the maximum damage peak. Silicon was found to disorder the material more completely than Al, and the disordered region extended to a depth greater than two times the projectile range. The effects of different annealing conditions on the disordering are discussed. We also implanted samples through high resolution ion masks and studied the disorder profile by TEM. The study revealed that the lateral disorder front follows that expected from the straggle of implanted ions. The feasibility of patterning with lateral resolution better than 30 nm is demonstrated. We have observed structure in spatially resolved cathodoluminescence, which we believe to arise from reduced dimensionality laterally patterned quantum wells.
Re: EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells is Polycomb-Independent (2013)

No AccessJournal of UrologyInvestigative Urology1 Jul 2013Re: EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells is Polycomb-Independent Anthony AtalaM.D. Anthony AtalaAnthony Atala More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.03.100AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Re: EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells is Polycomb-Independent." The Journal of Urology, 190(1), p. 358 © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 190Issue 1July 2013Page: 358Supplementary Materials Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Anthony Atala More articles by this author Expand All Advertisement PDF DownloadLoading ...
Quantitative curvature maps of the ocular posterior segment utilizing OCT with demonstration of local shape change over time (Conference Presentation) (2020)

Ocular morphological deformations, such as scleral flattening due to high intracranial pressure, result in both global and more difficult to detect local changes. Local curvature analysis of the retinal profile could help in the visualization of retinal morphological deformations. Using a wide-field, whole eye OCT system, we demonstrate quantitative local, meridional retinal curvature maps across a 12 mm field-of-view. Because our method provides absolute (instead of relative) quantitative maps of local curvature, comparisons can be made directly between individuals. Additionally, retinal topography could help clinicians detect subtle, local retinal deformations earlier in patients and track changes over time.
Challenges and Progress on Carbon Nanotube Integration for BEOL Interconnects (2018)

Here, we review and present current challenges and progress on Carbon Nanotube Integration for BEOL Interconnects as well as our recent results. Amongst all the research on carbon nanotube interconnects, those discussed here cover 1) improvement of the variability of SWCNTs for local interconnects 2) process & growth of carbon nanotube interconnects compatible with BEOL integration and formation of CNT-copper-composites, 3) modeling and simulation from atomistic to circuit-level benchmarking and performance prediction, and 4) characterization and electrical measurements. The aim is to evaluate the use of CNT-based materials for future metallization, both in regards to manufacturability, i.e. CMOS compatibility and wafer-scale integration as well as realistic performance expectations, i.e. variability and defectivity.
Inhibition of the Bruton Tyrosine Kinase Pathway in B-Cell Lymphoproliferative Disorders (2016)

Activation of the Bruton tyrosine kinase (BTK) pathway plays an important role in the pathophysiology of a number of B-cell lymphoproliferative disorders (LPDs). A number of preclinical studies support inhibiting BTK as a mechanism to treat LPDs. Clinically, BTK inhibitors, specifically ibrutinib, have shown to be safe and effective on treating patients with indolent B-cell lymphomas and chronic lymphocytic leukemia (CLL). Ibrutinib has recently gained approval for the treatment of patients with mantle cell lymphoma, Waldenström macroglobulinemia, and CLL. Ongoing clinical trials are investigating ibrutinib and other BTK inhibitors alone or in combination for the treatment of mantle cell lymphoma, Waldenström macroglobulinemia, CLL, activated B-cell-type diffuse large B-cell lymphoma, and follicular lymphoma, among others. The objective of this review is to succinctly summarize the current body of evidence on BTK inhibition in patients with B-cell LPDs.
Cost effective VCSEL array based 80-Gb/s TOSA for NG-PON2 (2014)

The 8×10 Gb/s TOSA based on a VCSEL array was successfully developed for NG-PON2 application. For the cost effectiveness, direct optical coupling without lens array was used to package the TOSA. We have found that an optical and electrical crosstalk was small enough not to effect on a transmission performance.