gebhart/patrepeval huggingface dataset:
Au−PbS Core−Shell Nanocrystals: Plasmonic Absorption Enhancement and Electrical Doping via Intra-particle Charge Transfer (2008)

We present a comparative study of optical and electronic properties for PbS nanocrystals and Au-PbS core-shell nanostructures. In Au-PbS nanostructures, we observed two nontrivial synergistic effects: (i) extinction enhancement due to coupling of surface plasmon resonance in the Au core to the excitonic states in the semiconducting PbS shell, and (ii) strong p-type electronic doping of Au-PbS nanocrystal solids that we explained by the intraparticle charge transfer between the PbS shell and the Au core.
Solar Energy for Biofuel Extraction (2018)

One of the most complex challenges of today is managing greenhouse gas emissions produced by excessive use of fossil fuels as energy source. With fossil fuels dominating the energy production, the sustainable and environmental problems will continue unless alternative sources of energy are put in place. Biomass is considered as a promising sustainable energy source which can be introduced to our energy mix. One way of converting raw biomass to higher value biofuels is following the thermochemical conversion processes, which include pyrolysis, gasification, torrefaction, combustion, and distillation. However, these processes typically require heat energy to treat the biomass, which is often supplied from non-renewable energy sources. This greatly reduces the conversion efficiency and causes environmental problems. Utilization of solar energy for assisting the biomass conversion through thermochemical conversion process significantly improves the overall sustainability and process performance. This work reviews the solar-based technologies and their application to solar-assisted biomass utilization and conversion technologies. The review then discusses outcomes of different solar-assisted biomass pyrolysis and gasification processes performed to date. It also presents the status of solar-assisted distillation for improving ethanol concentration.
Volatile Anesthetics Enhance Flash-induced γ Oscillations in Rat Visual Cortex (2005)

These findings suggest that a reduction in flash-induced gamma oscillations in rat visual cortex is not a unitary correlate of anesthetic-induced unconsciousness.
Tunneling Images of Gallium on a Silicon Surface: Reconstructions, Superlattices, and Incommensuration (1988)

Real-space images of an incommensurate superlattice on a monolayer-gallium-covered silicon (111) surface have been obtained with the tunneling microscope. Large, internally ordered supercells which in turn form a lattice with discrete boundaries are observed. A graphitelike silicon-gallium top layer is suggested that is weakly bonded to the lattice below and stabilized by a periodic array of misfit dislocations. This model unifies reflection high-energy electron diffraction, x-ray standing-wave, and tunneling observations.
Graphene Nanocomposites: Sandwich‐Type Nanocomposite of Reduced Graphene Oxide and Periodic Mesoporous Silica with Vertically Aligned Mesochannels of Tunable Pore Depth and Size (Adv. Funct. Mater. 47/2017) (2017)

In article number 1704066, Zheng-Ming Wang and co-workers report a sandwich-type nanocomposite of reduced graphene oxide and periodic mesoporous silica in which mesochannels of silica are vertically aligned toward graphene layers and mesochannel depth and size become tunable. Deep insights into the formation mode are obtained by high photon flux small angle X-ray scattering technique and zeta potential-based solution chemistry.
Pathogenesis of Ovarian Serous Carcinoma as the Basis for Immunologic Directed Diagnosis and Treatment. Project 2 - Identification of Autologous Antigens in Early Stage Serous Carcinoma (2003)

Abstract : Our goal is to develop an early detection screening test for serous carcinoma. Specific aim 1: Obtain cDNAs of autologous tumor antigens recognized by sera of patients with early stage serous carcinoma, but not controls. Progress: While our ovarian cancer cDNA library is construction for SEREX analysis, we have developed an alternative, complementary methodology. We employed patient sera to immunoprecipitate proteins from autologous cancer cells and identified these antigens by mass spectrometry. One antigen, SMAP-1, has homology to genes that facilitate cell division. Specific aim 2: Identify autologous tumor antigens expressed in serous carcinoma but absent from, or a low level in normal tissue. Progress: We have expressed recombinant SMAP-1 protein and generated specific antisera. We the SMAP-1 mRNA is ubiquitous in all tissues tested thus far, and immunohistochemical studies are currently underway. We have already several identified several other SEREX antigens, including the homeobox HOXB7 transcription factor. We have generated peptide antiserum to HOXB7 and confirmed its over expression in cancer cell lines. Interestingly, we also note a shift from a nuclear localization in normal tissue to the cytoplasm in most carcinomas.
Deep Remission: A New Concept? (2012)

Crohn's disease (CD) is a chronic inflammatory disorder characterized by periods of clinical remission alternating with periods of relapse defined by recurrent clinical symptoms. Persistent inflammation is believed to lead to progressive bowel damage over time, which manifests with the development of strictures, fistulae and abscesses. These disease complications frequently lead to a need for surgical resection, which in turn leads to disability. So CD can be characterized as a chronic, progressive, destructive and disabling disease. In rheumatoid arthritis, treatment paradigms have evolved beyond partial symptom control alone toward the induction and maintenance of sustained biological remission, also known as a 'treat to target' strategy, with the goal of improving long-term disease outcomes. In CD, there is currently no accepted, well-defined, comprehensive treatment goal that entails the treatment of both clinical symptoms and biologic inflammation. It is important that such a treatment concept begins to evolve for CD. A treatment strategy that delays or halts the progression of CD to increasing damage and disability is a priority. As a starting point, a working definition of sustained deep remission (that includes long-term biological remission and symptom control) with defined patient outcomes (including no disease progression) has been proposed. The concept of sustained deep remission represents a goal for CD management that may still evolve. It is not clear if the concept also applies to ulcerative colitis. Clinical trials are needed to evaluate whether treatment algorithms that tailor therapy to achieve deep remission in patients with CD can prevent disease progression and disability.
Adaptive blind channel identification: Multi-channel least mean square and Newton algorithms (2002)

The problem of identifying a single-input multiple-output FIR system without a training signal, the so-called blind system identification, is addressed and two adaptive multi-channel approaches, least mean square (LMS) and Newton algorithms, are proposed. In contrast to the existing batch blind channel identification schemes, the proposed algorithms construct an error signal based on the cross relations between different channels in a novel, systematic way. The corresponding cost (error) function is easy to manipulate and facilitates the use of adaptive filtering methods for an efficient blind channel identification scheme. It is theoretically shown and practically demonstrated by numerical studies that the proposed algorithms converge in the mean to the desired channel impulse responses for an identifiable system.
Blind single-channel suppression of late reverberation based on perceptual reverberation modeling (2011)

A blind method for suppressing late reverberation from speech and audio signals is presented. The proposed technique operates both on the spectral and on the sub-band domains employing a single input channel. At first, a preliminary rough clean signal estimation is required and for this, any standard technique may be applied; however here the estimate is obtained through spectral subtraction. Then, an auditory masking model is employed in sub-bands to extract the reverberation masking index (RMI) which identifies signal regions with perceived alterations due to late reverberation. Utilizing a selective signal processing technique only these regions are suppressed through sub-band temporal envelope filtering based on analytical expressions. Objective and subjective measures indicate that the proposed method achieves significant late reverberation suppression for both speech and music signals over a wide range of reverberation time (RT) scenarios.
PRC2 loss of function confers a targetable vulnerability to BET proteins in T-ALL (2021)

T-cell acute lymphoblastic leukemia (T-ALL) is a group of aggressive hematological cancers with dismal outcomes that are in need of new therapeutic options. Polycomb repressor complex 2 (PRC2) loss-of-function alterations were reported in pediatric T-ALL, yet their clinical relevance and functional consequences remain elusive. Here, we extensively analyzed PRC2 alterations in a large series of 218 adult T-ALL patients. We found that PRC2 genetic lesions are frequent events in T-ALL and are not restricted to early thymic precursor ALL. PRC2 loss of function associates with activating mutations of the IL7R/JAK/STAT pathway. PRC2-altered T-ALL patients respond poorly to prednisone and have low bone marrow blast clearance and persistent minimal residual disease. Furthermore, we identified that PRC2 loss of function profoundly reshapes the genetic and epigenetic landscapes, leading to the reactivation of stem cell programs that cooperate with bromodomain and extraterminal (BET) proteins to sustain T-ALL. This study identifies BET proteins as key mediators of the PRC2 loss of function-induced remodeling. Our data have uncovered a targetable vulnerability to BET inhibition that can be exploited to treat PRC2-altered T-ALL patients.
Molecular Biology and Pathology of Lymphangiogenesis (2007)

The lymphatic vasculature is essential for the maintenance of tissue fluid balance, immune surveillance, and adsorption fatty acids in the gut. The lymphatic vessels are also crucially involved in the pathogenesis of diseases such as tumor metastasis, lymphedema, and various inflammatory conditions. Attempts to control or treat these diseases have drawn a lot of interest to lymphatic vascular research during the past few years. Recently, several markers specific for lymphatic endothelium and models for lymphatic vascular research have been characterized, enabling great technical progress in lymphatic vascular biology, and many critical regulators of lymphatic vessel growth have been identified. Despite these significant achievements, our understanding of the lymphatic vessel development and pathogenesis is still rather limited. Several key questions remain to be resolved, including the relative contributions of different pathways targeting lymphatic vasculature, the molecular and cellular processes of lymphatic maturation, and the detailed mechanisms of tumor metastasis via the lymphatic system.
Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans (2012)

α(1) - and β-Adrenoceptors contribute to the cardiostimulant and thermogenic effects of MDMA in humans but not to its psychotropic effects. Carvedilol could be useful in the treatment of cardiovascular and hyperthermic complications associated with ecstasy use.
Magnesium aspartate hydrochloride attenuates monocrotaline-induced pulmonary artery hypertension in rats (1988)

1. The effect of oral magnesium aspartate hydrochloride on monocrotaline (MCT)-induced pulmonary arterial hypertension was evaluated in rats. 2. A single subcutaneous injection of MCT, a pyrrolizidine alkaloid of plant origin, induces significant morphological changes in pulmonary vessels, pulmonary arterial hypertension and right ventricular hypertrophy in rats by 3 weeks. 3. Two groups of rats (Mg2+ control and Mg2+ + MCT) were started on oral Mg2+ (15.4 g/l magnesium aspartate hydrochloride dissolved in deionized water) 2 weeks before the MCT injection. The rest were given deionized water. At the start of the experiment, the control groups (deionized water and Mg2+) were given normal saline subcutaneously; the other groups (deionized water and Mg2+) were given MCT (60 mg/kg) subcutaneously. 4. Pulmonary artery pressure, right ventricular hypertrophy, lung pathology, organ weights and serum electrolytes were assessed 3 weeks after a single subcutaneous injection of MCT. Seventy-five per cent of the rats treated with MCT and oral Mg2+ (12 out of 16) showed significant reduction in pulmonary arterial hypertension, arterial pathology and right ventricular hypertrophy. 5. Our data indicate that Mg2+ attenuates experimentally induced pulmonary hypertension, possibly either by modulating the intracellular Ca2+ level and/or by directly affecting the pulmonary endothelial cell-smooth muscle cell complex involved in metabolism and maintenance of pulmonary vascular resistance.
Compensation Network for a 7.7 kW Wireless Charging System that Uses Standardized Coils (2020)

Industrial wireless charging systems use standardized coils to guarantee interoperability between different manufacturers. In combination with these coils, the compensation network can still be designed and optimized. This paper explains the step-by-step design of the compensation network for a 7.7 kW wireless charging system (power class WPT2), which is composed of standardized coils. The compensation network must satisfy the output power and voltage requirements, the soft-switching of the inverter, and the limit of voltage and current stress on the components. The S-S compensation network is found to be unfeasible for those coils, and an optimized double-sided LCC compensation network is designed. The 3-phase grid connection is selected despite the 1-phase one because it gives the lowest total conduction losses. Finally, two parallel SiC MOSFETs C3M0075120K are chosen as inverter's switch because of their low conduction losses. This solution can achieve a payback time within a year with respect to the cheapest one.
Right‐sided vagus nerve stimulation inhibits induced spinal cord seizures (2005)

We have previously shown that left-sided vagus nerve stimulation results in cessation of induced spinal cord seizures. To test our hypothesis that right-sided vagus nerve stimulation will also abort seizure activity, we have initiated seizures in the spinal cord and then performed right-sided vagus nerve stimulation in an animal model. Four pigs were anesthetized and placed in the lateral position and a small laminectomy performed in the lumbar region. Topical penicillin, a known epileptogenic drug to the cerebral cortex and spinal cord, was next applied to the dorsal surface of the exposed cord. With the exception of the control animal, once seizure activity was discernible via motor convulsion or increased electrical activity, the right vagus nerve previously isolated in the neck was stimulated. Following multiple stimulations of the vagus nerve and with seizure activity confirmed, the cord was transected in the midthoracic region and vagus nerve stimulation performed. Right-sided vagus nerve stimulation resulted in cessation of spinal cord seizure activity in all animals. Transection of the spinal cord superior to the site of seizure induction resulted in the ineffectiveness of vagus nerve stimulation in causing cessation of seizure activity in all study animals. As with left-sided vagus nerve stimulation, right-sided vagus nerve stimulation results in cessation of induced spinal cord seizures. Additionally, the effects of right-sided vagus nerve stimulation on induced spinal cord seizures involve descending spinal pathways. These data may aid in the development of alternative mechanisms for electrical stimulation for patients with medically intractable seizures and add to our knowledge regarding the mechanism for seizure cessation following peripheral nerve stimulation.
Measurement of the Localized Viscosity of Molecular Assemblies Using Nanoscopic Defects Induced with the Scanning Tunneling Microscope (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMeasurement of the Localized Viscosity of Molecular Assemblies Using Nanoscopic Defects Induced with the Scanning Tunneling MicroscopeJorma A. Virtanen, Samuel Lee, Wenjie Li, and Reginald M. PennerCite this: J. Phys. Chem. 1994, 98, 10, 2663–2667Publication Date (Print):March 1, 1994Publication History Published online1 May 2002Published inissue 1 March 1994https://pubs.acs.org/doi/10.1021/j100061a025https://doi.org/10.1021/j100061a025research-articleACS PublicationsRequest reuse permissionsArticle Views33Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Ring-Opening Polymerization: Introduction (1985)

The principal purpose of this paper is to provide a suitable introduction to the remaining 25 papers that comprise this book. As mentioned earlier in the Preface, this book is a result of a symposium presented in 1984 under the auspices of the Polymer Division of the American Chemical Society. Most of the speakers at the symposium have chosen to prepare manuscripts to further illustrate the research conducted in their own laboratories. A minority of these speakers chose to publish their work elsewhere. We have in fact been able to publish 26 of the 32 lectures which represents a substantial majority of those presented at the meeting. The range of topics discussed is quite broad and therefore should be of considerable interest to many scientists and engineers in both academic and industrial institutions around the world. The subjects include fundamental and applied research on the polymerization of cyclic ethers, siloxanes,
SiGe bipolar transistor modeling for a full chip ESD simulation (2009)

A new compact model compatible with industry standard circuit simulation tools is developed to predict the current and voltage characteristics of SiGe bipolar transistors beyond their breakdown. This is a region of interest for circuit simulations during ESD (electro-static discharge) events. The enhanced bipolar models are benchmarked versus device-level TLP (transmission line pulse) measurements and used in full-chip ESD event simulation for identifying design weaknesses and optimizing emerging circuit designs for ESD robustness.
Ratiometric Detection of Nerve Agents by Coupling Complementary Properties of Silicon-Based Quantum Dots and Green Fluorescent Protein (2019)

Ratiometric photoluminescent detection of the toxicologically potent organophosphate ester nerve agents paraoxon (PX) and parathion (PT) using the complementary optical and chemical properties of the long Stokes shift green fluorescent protein variant, mAmetrine1.2 (mAm), and red-emitting silicon-based quantum dots (SiQDs) is reported. PX and PT selectively quench SiQD photoluminescence (PL) through a dynamic quenching mechanism, thereby, facilitating the development of a ratiometric sensor platform that shows micromolar limits of detection for PX and PT and that is unaffected by the presence of common inorganic and organic interferents. As a part of the present study, we also demonstrate that the paper-based sensors derived from mAm and SiQDs detect PX and PT at concentrations as low as 5 μM using a readily available commercial color analysis smartphone "app". The ratiometric sensor reported herein can potentially be used for the convenient and rapid on-site detection and quantification of PX and PT in real-world samples.
New Dammarane Saponins from the Steamed Ginseng Leaves (2010)

indicated the presence of partial structures written in bold lines; and in the HMBC spectrum, the long-range correlations were observed between the follow-ing protons and carbons: H-6 and C-8; H-12 and C-9,17; H-18 and C-7,9,14; H-19 and C-1,5,9; H-21 C-22; H-22C-17,24; H-24 and C-22,26; H-26 and C-24; H-27 and C-24; H-1' and C-6, respectively. Consequently, the structure of gin-senoside ST
Imidazo[2,1]thiazol-3-one Derivatives Useful as Diagnostic Agents for Alzheimer’s Disease (2014)

ADVERTISEMENT RETURN TO ISSUEPREVPatent HighlightNEXTImidazo[2,1]thiazol-3-one Derivatives Useful as Diagnostic Agents for Alzheimer's DiseaseBenjamin Blass*View Author Information Temple University School of Pharmacy, 3307 North Broad Street, Philadelphia, Pennsylvania 19140, United States*Tel: 215-707-1085. E-mail: [email protected]Cite this: ACS Med. Chem. Lett. 2014, 5, 6, 619–620Publication Date (Web):April 28, 2014Publication History Received11 April 2014Published online28 April 2014Published inissue 12 June 2014https://pubs.acs.org/doi/10.1021/ml500147nhttps://doi.org/10.1021/ml500147neditorialACS PublicationsCopyright © 2014 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views1029Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (243 KB) Get e-AlertscloseSUBJECTS:Alkyls,Group 17 compounds,Hydrogen,Nervous system diseases,Reaction products Get e-Alerts
Co‐culture of adipose‐derived stem cells and chondrocytes on three‐dimensionally printed bioscaffolds for craniofacial cartilage engineering (2018)

NA. Laryngoscope, 128:E251-E257, 2018.