gebhart/patrepeval huggingface dataset:
Myocardial infarction, cardiac anatomy and ventricular loading. (1993)

To see whether the hypertrophic response of the surviving myocardium after infarction leads to a complete reconstitution of ventricular mass, the left coronary artery was ligated in rats and the animals killed one month later. In infarcts affecting an average of 38% of the free wall of the left ventricle, the ratio of wall thickness to chamber radius remained essentially constant. On the other hand, the ratio decreased significantly in the presence of infarcts involving an average of 60% of the ventricular wall. In addition, inadequate growth adaptations were detected in both groups of infarcts with respect to myocyte volume and length and to capillary volume and length. These defects in the regeneration of myocardial structures were associated with elevations in diastolic wall stress which were more prominent in the larger infarct group. The limited growth reaction of the myocyte and vascular compartments may be implicated in the persistence of cardiac dysfunction and failure late after infarction.
Clinical value of F18-fluorodeoxyglucose positron emission tomography-computed tomography in patients with non-small cell lung cancer after potentially curative surgery: experience with 241 patients (2010)

The present study demonstrated the high diagnostic performance of FDG-PET/CT in detecting recurrences in a large group of patients with NSCLC after potentially curative surgery. FDG-PET/CT is useful not only for diagnosis of recurrence but also for detection of other diseases.
Process development for high scan speed ArF immersion lithography (2008)

It has been found that 193nm immersion lithography technology can achieve smaller patterns without any modification to the technology infrastructure of existing state-of-the-art 193nm dry lithography. This has made 193nm immersion lithography a promising technology for mass production processes. Recently, scanning speed of the exposure stage has been increasing in order to achieve high throughput for mass production. At present, the adoption of a topcoat is one of the promising candidates for this high speed scanning process. On the other hand, the demand for a non-topcoat process is being pursued from a C.O.O. (cost of ownership) point of view but there are still issues being revealed and concerns to be solved. In this report, feasibility of a comprehensive process for high scanning ArF immersion lithography was discussed. As for the topcoat process, a high receding contact angle topcoat, such as TC-A (JSR), is proving to be a good candidate for mass production using high scanning speed immersion lithography. TC-A has a similar defectivity and lithographic performance to TCX041 (JSR). On the other hand, the feasibility of a non-topcoat process was also investigated. CD uniformity, defectivity and lithography performance of AIM5120JN and AIM5570JN (JSR) data indicate that the non-topcoat process can be adopted for mass production process. An immersion cluster comprised of a high volume production immersion exposure tool, S610C (NIKON) having 1.3 NA and CLEAN TRACK<sup>TM</sup> LITHIUS<sup>TM</sup> i+ (TEL) track system were used in this study.
Lateral control of platoons of vehicles on highways: the autonomous following based approach (2004)

Automated driving of vehicles on highways may be accomplished by dividing the control problem in the longitudinal and lateral direction. In this paper, the problem of lateral control of vehicles operating in a platoon without the use of road infrastructure, that is, autonomous following, is considered. Firstly, the limitations of autonomous following without inter-vehicle communication are uncovered. Specifically, the influence of rear end off-tracking and look-ahead distance on the accuracy of lane following is illustrated. Next, the notion of string stability for a platoon is introduced. It is shown that the interconnected platoon without inter-vehicle communication theoretically can be string stable at the expense of poor performance. Finally, it is shown that, under certain circumstances, the addition of inter-vehicle communication eliminates the interconnection with the rest of the vehicles in the platoon, resulting in accurate lane following. The analytical results are verified by simulations and experiments.
Prognostic value of c-erbB2 overexpression in axillary lymph node positive breast cancer. Results from a randomized adjuvant treatment protocol (1994)

According to this analysis, the strong correlation between c-erbB2 expression and degree of nodal involvement, higher grade disease, and estrogen receptor negativity suggests expression of this protooncogene product in a biologically more aggressive form of breast cancer. In a multivariate analysis, c-erbB2 expression was not an independent prognostic factor. Thus, c-erbB2 assessment did not appear to add significantly to the information provided by currently available standard disease parameters.
Effect of Polypropylene Fibers on Oil-Well Cement Properties at HPHT Condition (2018)

Abstract In deeper wells, high pressure and temperature post cementing operations put extreme stresses on the cement sheath and dramatically affect the cement integrity. So, the design of the cement slurry is very important to ensure the durability and long-term integrity of the cement sheath. The design should lead to a better zonal isolation and strengthen the bonding with the casing. Furthermore, it should help to shield the casing from corroding and unpredictable shock loads in deeper zones and sustain plugs to control the lost circulation in fractured and high permeability zones. Different additives were used to provide these functions such as; polymers, fibers, and bio-medicine in concrete history. Because of their large surface areas and small size, those particles are highly being used in the petroleum industry in the latest decades. In this study, the usage of polypropylene fibers (PPF) is evaluated for oil well cement at high pressure and high temperature (HPHT) condition. The polypropylene fibers were added to the base cement in a different amount to evaluate its influence on enhancing the performance of cement. The results obtained showed that adding polypropylene fiber to the base cement has a negligible effect on cement density, rheological properties, and free water. Using polypropylene fiber (0.75% base weight of cement (BWOC)) with the base cement reduced the thickening time by 75%; from 317 minutes to 78 minutes. The addition of Polypropylene fiber (0.5% BWOC) increased the compressive strength of class G cement by 17.8%. Polypropylene fiber can be used as an alternative material for silica floor in shallow wells. Polypropylene fiber has a significant effect on reducing the porosity and the permeability of the base cement.
Endotoxin infusion in anesthetized sheep is associated with intrapulmonary sequestration of leukocytes that immunohistochemically express tumor necrosis factor-α (1995)

Plasma levels of tumor necrosis factor-alpha (TNF-alpha) peak between 2 and 4 h during a 12-h continuous infusion of endotoxin in awake sheep. We hypothesized that a source of this TNF-alpha is the pool of leukocytes that accumulate in the pulmonary circulation. To test this hypothesis, we physiologically monitored six anesthetized sheep during baseline and 4-h endotoxin infusion periods (10 ng/kg x min). We obtained open-lung biopsies at baseline and at 20 min and 2 and 4 h during the endotoxin infusion period for immunohistochemical localization of TNF-alpha. The plasma concentration of TNF-alpha increased from an average baseline concentration of 0.06 +/- 0.03 ng/ml (mean +/- SD) to a peak of 1.40 +/- 0.28 ng/ml at 2 h of the endotoxin infusion. We observed increased cytoplasmic TNF-alpha immunoreactivity in situ among neutrophils and intravascular mononuclear phagocytes during the endotoxin infusion compared with baseline. Also, the number of immunopositive leukocytes increased in the pulmonary circulation during the continuous infusion of endotoxin. We conclude that TNF-alpha-producing leukocytes accumulate in the pulmonary circulation during endotoxemia. These cells probably contribute to both the rise in the circulating levels of TNF-alpha and the development of acute lung injury.
Sudden death from pulmonary thromboembolism: Chronobiological aspects (1992)

The aim of this study was to determine whether sudden cardiac death from pulmonary embolism exhibits any chronobiological rhythm. Five hundred and seven consecutive subjects dying suddenly outside of hospital and brought into our Emergency Department from January 1983 to December 1989 were studied. The time and date of event were accurately recorded. All subjects underwent autopsy and 48 of them were found to have died of pulmonary embolism (23 males, mean age 73.9 +/- 8 years and 25 females, mean age 76 +/- 12 years). All data were analysed by means of single cosinor[19,20]. In the subjects with pulmonary emboli both a circadian and a circannual rhythmicity were found, with a significant acrophase respectively in the morning (h.min. 11.46, P = 0.003) and in winter (-19.3, P = 0.009).
Low threshold 1.3μm InAsP/InP Strained Layer Quantum Well Laser Diodes Grown by Metalorganic Chemical Vapor Deposition (2005)

A very low threshold current density of 450A/cm/sup 2/ was obtained in a novel 1.3/spl mu/m InAsP/InP strained layer quantum well laser diode (LD) for the first time. Threshold current as low as 5.5mA was obtained in a buried heterostructure LD.
Effect of gestational variation of phosphatidylglycerol and phosphatidylinositol on the microviscosity of amniotic fluid phospholipids. (1980)

Journal Article Effect of gestational variation of phosphatidylglycerol and phosphatidylinositol on the microviscosity of amniotic fluid phospholipids. Get access H S Cheskin, H S Cheskin Search for other works by this author on: Oxford Academic Google Scholar T A Blumenfeld, T A Blumenfeld Search for other works by this author on: Oxford Academic Google Scholar P C Beers, P C Beers Search for other works by this author on: Oxford Academic Google Scholar V Buddega V Buddega Search for other works by this author on: Oxford Academic Google Scholar Clinical Chemistry, Volume 26, Issue 2, 1 February 1980, Pages 301–304, https://doi.org/10.1093/clinchem/26.2.301 Published: 01 February 1980
Images in cardiovascular medicine. Detection of luminal-intimal border and coronary wall enhancement in intravascular ultrasound imaging after injection of microbubbles ans simultaneous sonication with transthoracic echocardiography (2005)

peer reviewed
Polyester-styrene/ceramic nanocomposites for antenna applications (2013)

Polyester-styrene polymer composites of high permittivity ceramic nano powders (barium titanate) are fabricated and electrically measured for antenna applications. It is shown that the usage of high permittivity ceramic contents can increase the relative permittivity of the composites to around 10 at microwave frequencies. The Polyester-styrene composite material preparation technique is described. The materials are used to fabricate various dielectric resonator antenna elements. Details of the antenna fabrication techniques are discussed. Results show fabricated antenna elements and arrays with large impedance bandwidth. The presented techniques provide a precise method for fabrication of complicated or multi-segment dielectric resonator antennas.
Polarization transfer solid-state NMR: a new method for studying cellulose dissolution (2014)

Detailed molecular-level information on dissolved and solid cellulose in aqueous dissolution media with ionic liquids by polarization transfer solid-state NMR.
Automatic selection of region of interest for radiographic texture analysis (2007)

We have been developing radiographic texture analysis (RTA) for assessing osteoporosis and the related risk of fracture. Currently, analyses are performed on heel images obtained from a digital imaging device, the GE/Lunar PIXI, that yields both the bone mineral density (BMD) and digital images (0.2-mm pixels; 12-bit quantization). RTA is performed on the image data in a region-of-interest (ROI) placed just below the talus in order to include the trabecular structure in the analysis. We have found that variations occur from manually selecting this ROI for RTA. To reduce the variations, we present an automatic method involving an optimized Canny edge detection technique and parameterized bone segmentation, to define bone edges for the placement of an ROI within the predominantly calcaneus portion of the radiographic heel image. The technique was developed using 1158 heel images and then tested on an independent set of 176 heel images. Results from a subjective analysis noted that 87.5% of ROI placements were rated as "good". In addition, an objective overlap measure showed that 98.3% of images had successful ROI placements as compared to placement by an experienced observer at an overlap threshold of 0.4. In conclusion, our proposed method for automatic ROI selection on radiographic heel images yields promising results and the method has the potential to reduce intra- and inter-observer variations in selecting ROIs for radiographic texture analysis.
Challenges for Model-Based Diagnosis (2019)

Since the seminal works by Reiter and de Kleer and Williams published in the late 80’s, Model-based Diagnosis has been a significant area of research. This has been motivated by the fact that MBD assists us in tackling a challenge that we face almost on a daily basis, i.e., by MBD allowing us to reason in a structured manner about the root causes for some encountered problem. MBD achieves this in an intuitive, complete and sound way, based on the central idea of investigating the compliance of some observed behavior with a model that describes how a system should behave - given this or that input scenario and parameter set. Over the last 40 years, MBD has been adopted for a multitude of applications, and we saw the emergence of a diverse set of algorithmic, optimizations, as well as extensions to the initial theoretical concepts.We argue that MBD remains highly relevant, with numerous scientific challenges to tackle as we face increasingly complex diagnostic problems. We discuss several such challenges and suggest related topics for PhD theses that have the potential to significantly contribute to the state-of-the-art in MBD research.
Ozone Sparging Closure of an Industrial VOC Spill Site Adjacent to a Water Supply Well Site (2008)

Ozone sparging using the KTI C-Sparge™ process was performed on an industrial site adjacent to a major water supply well site. Ozone sparging was initiated in February, 2000, and groundwater volatile organic compound concentrations in downgradient wells decreased as much as 95 percent by the end of 2001. From 2003 to closure in 2006, the responsible party continued treatment with monitored attenuation and combined source treatment with a barrier region rather than more aggressively attack plant source areas. Initial remedial actions included source excavation (1996), a Fenton's Reagent flood (1998), followed by ozone sparging. The regulatory agency accepted ozone sparging for source treatment and temporary barrier as the most desirable alternative. Monitored attenuation was not acceptable without source reduction and elimination. Continued operation of the facility progressed during remedial treatment. Closure was obtained with the region achieving MCLs (Minimum Contaminant Levels) at the operational water supply wells and on the industrial site boundary. Final groundwater removal was in excess of 99%. No adverse water quality impacts were found during treatment at the water supply wellheads.
Pb[sub 2]Ru[sub 2]O[sub 6.5] as a Low-Temperature Cathode for Bismuth Oxide Electrolytes (2005)

A chemical route, called direct condensation method (DCM), was developed to synthesize nanometric as a cathode material for intermediate temperature solid oxide fuel cells. The electrolyte used was (ESB). Porous lead ruthenate and ESB-lead ruthenate composite electrodes were deposited onto dense ESB pellets. X-ray diffraction, field-emission scanning electron microscopy, and energy dispersive spectroscopy analysis were used to investigate the reactivity and the morphology of the materials prepared. Electrochemical impedance spectroscopy in air at different operating temperatures was used to evaluate polarization and electrical performance of cells in symmetric configuration. Lead ruthenate-based electrodes were sintered at different temperatures to understand the role of the triple-phase boundary on the electrode polarization. An increase in the sintering temperature induced the formation of intermediate phases at the interface between ESB and the pyrochlore, thereby resulting in an increase in the polarization resistance at the electrode/electrolyte interface of the symmetric cells.
Structure-Guided Improvement of a Dual HPIV3/RSV Fusion Inhibitor (2020)

Human parainfluenza virus 3 (HPIV3) and respiratory syncytial virus (RSV) are leading causes of lower respiratory tract infections. There are currently no vaccines or antiviral therapeutics to treat HPIV3 or RSV infections. We recently reported a peptide (VIQKI), derived from the C-terminal heptad repeat (HRC) domain of the HPIV3 fusion (F) glycoprotein that inhibits infection by both HPIV3 and RSV. The dual inhibitory activity of VIQKI is due to its unique ability to bind to the N-terminal heptad repeat (HRN) domains of both HPIV3 and RSV F, thereby preventing the native HRN-HRC interactions required for viral entry. Here we describe the structure-guided design of dual inhibitors of HPIV3 and RSV fusion with improved efficacy. We show that VIQKI derivatives possessing one (I456F) or two (I454F/I456F) phenylalanine substitutions near the N-terminus exhibit more stable assemblies with the RSV-HRN domain and enhanced antiviral efficacy against both HPIV3 and RSV infection. Cocrystal structures of the new Phe-substituted inhibitors coassembled with HPIV3 or RSV-HRN domains reveal that the I456F substitution makes intimate hydrophobic contact with the core trimers of both HPIV3 and RSV F.
Enhancement of process latitude by reducing resist thickness for KrF excimer laser lithography (1998)

Reducing resist thickness easily and simultaneously decreases the k1 factor and increases the k2 factor in conventional Rayleigh equations, without changing the wavelength of the illumination light and NA of the optics. In this work, we investigated the effect of reduced resist thickness on process latitude and optical proximity effect (OPE) at the sub-quarter micron level. The experiment exposures were performed by a 0.6 NA KrF excimer step and scan system with an in-house chemically amplified positive resist in the thickness range of 0.6 micrometers to 0.25 micrometers . The results showed remarkable improvements in process latitude of both 0.175 micrometers L&S and 0.225 micrometers contact hole, as well as OPE such as a CD variation between different pitches and a feature deformation at isolation by reducing resist thickness.
Near‐field characterization of photonic crystal Y‐splitters (2005)

A scanning near-field optical microscope (SNOM) is used to directly map the propagation of light in a specially designed 50/50 photonic crystal (PC) Y-splitter fabricated on silicon-on-insulator (SOI) wafers. SNOM images are obtained for TE- and TM-polarized light in the wavelength range 1425–1570 nm. The recorded intensity distributions exhibit highly wavelength (and polarization) dependent intensity variations along the propagation direction, especially around the fork and bend regions. By comparing the SNOM images recorded in and after the PC Y-splitter area, the features of light distribution are analysed for both polarizations. (© 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
Application of a multi-phase multi-morphology crystallization model to isotactic polypropylenes with different molecular weight distributions (2017)

Flow-induced crystallization at elevated pressure of a set of metallocene isotactic polypropylenes (iPP) possessing different molecular weight distributions is studied using extended dilatometry experiments in an apparatus able to apply elevated pressure (up to 1200 bar) and strong shear flow (shear rates up to 180 s−1). The effect of flow on the crystallization temperature was quantified and the samples were analyzed using X-ray diffraction to measure the relative amounts of different crystal phases. The experimental results were used to test a flow induced crystallization model framework recently developed in our group which can describe the complex crystallization behavior of iPP and includes formation of multiple morphologies (spherulites, shish-kebab structure with lamellar branching) and crystal phases (α,β and γ). Almost all model parameters were left unchanged, except for the temperature description of the quiescent crystal growth rate and nucleation density (experimentally measured using optical microscopy) and an extra parameter which takes into account the fraction of high molecular weight for the creation of flow-induced nuclei. The model describes rather good the experimentally observed trends for what regards crystallization temperature and amount of α and γ-phase but substantial discrepancies were found in the amount of β-phase formed. This could be related to the presence of 2,1 insertion errors in metallocene samples which could inhibit the formation of this crystal phase.
Multiblock copolymers of poly(2,5‐benzophenone) and disulfonated poly(arylene ether sulfone) for proton‐exchange membranes. I. Synthesis and characterization (2006)

Abstract Nanophase‐separated, hydrophilic–hydrophobic multiblock copolymers are promising proton‐exchange‐membrane materials because of their ability to form various morphological structures that enhance transport. A series of poly(2,5‐benzophenone)‐activated, telechelic aryl fluoride oligomers with different block molecular weights were successfully synthesized by the Ni(0)‐catalyzed coupling of 2,5‐dichlorobenzophenone and the end‐capping agent 4‐chloro‐4′‐fluorobenzophenone. These telechelic oligomers (hydrophobic) were then copolymerized with phenoxide‐terminated, disulfonated poly(arylene ether sulfone)s (hydrophilic) by nucleophilic, aromatic substitution to form hydrophilic–hydrophobic multiblock copolymers. High‐molecular‐weight multiblock copolymers with number‐average block lengths ranging from 3000 to 10,000 g/mol were successfully synthesized. Two separate glass‐transition temperatures were observed via differential scanning calorimetry in the transparent multiblock copolymer films when each block length was longer than 6000 g/mol. Tapping‐mode atomic force microscopy also showed clear nanophase separation between the hydrophilic and hydrophobic domains and the influence of the block length as it increased from 6000 to 10,000 g/mol. Transparent and creasable films were solvent‐cast and exhibited moderate proton conductivity and low water uptake. These copolymers are promising candidates for high‐temperature proton‐exchange membranes in fuel cells, which will be reported separately in part II of this series. © 2006 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 45: 284–294, 2007