gebhart/patrepeval huggingface dataset:
Local measurements of the diffusion constant in multiple scattering media: Application to human trabecular bone imaging (2008)

Multiple scattering of ultrasound can occur in trabecular bones. A typical signature of multiple scattering is the coherent backscattering effect, and the average trajectory of a wave undergoing multiple scattering can be characterized by the diffusion constant D. In this work, we present local measurements of the diffusion constant for ultrasonic waves in human trabecular bone, based on near-field observation of the backscattered intensity. The experimental set up consists in an array of programmable transducers placed in front of a slice of bone that we want to image. By achieving Gaussian beamforming both at emission and reception, an array of virtual sources and receivers located in the near-field is constructed. The time evolution of the incoherent component of the intensity backscattered on this virtual array is shown to represent directly the growth of the diffusive halo as (Dt)1/2. A matrix treatment is proposed to separate the incoherent intensity from the coherent backscattering peak. Once the incoherent contribution is isolated, local measurements of the diffusion constant D are achieved around 3 MHz and then a D-map of the bone is built. These measurements are shown to be strongly correlated with the bone mineral density.
Device physics of quantum-well heterostructure MI<sup>3</sup>SFET's (1987)

A quantum-well heterostructure FET that is undoped except for a thin layer beneath the well and is fabricated in an ion-implanted self-aligned geometry is examined in experiments and computer simulations. Key aspects of the physics of this device, which relate to channel access, charge control, and deep-level trapping, are described.
Antibody to HSV gD peptide induced by vaccination does not protect against HSV-2 infection in HSV-2 seronegative women (2017)

AIDSVAX® B/E containing gD did not confer protection from HSV-2 acquisition in HSV-2 seronegative women, despite eliciting anti-gD serum antibodies.
Muscle Characteristics Obtained Using Computed Tomography as Prognosticators in Patients with Castration-Resistant Prostate Cancer (2020)

Limited studies have investigated the correlation between body composition and prostate cancer outcomes. We analyzed the effect of muscle mass and quality on castration-resistant prostate cancer (CRPC) outcomes. Skeletal muscle index (SMI) and skeletal muscle attenuation (SMA) were measured for 411 patients at the L3 vertebral level using computed tomography at CRPC diagnosis and were dived to low and high groups at the value of median. Analysis of the skeletal phenotypes and age (<70 and >70 years) was performed to evaluate the effect of SMI and SMA. The median survival rates for patients with low and high SMI were 19 and 24 months (<i>p</i> = 0.015), and those with low and high SMAs were 15 and 26 months (<i>p</i> < 0.001), respectively. In the subgroup analysis by age, SMA was a significant prognosticator in both groups, while SMI was a significant prognosticator only in patients aged >70 years. Patients with low SMA + low SMI had the worst prognosis. Muscle characteristics seems to be a prognosticator in survival of CRPC patients and may be considered in treatment planning.
Niemann-Pick disease type C2 presenting as fatal pulmonary alveolar lipoproteinosis: morphological findings in lung and nervous tissue. (2008)

Evidence that NPC2 is associated with severe pulmonary alveolar lipoproteinosis is supported. There were extensive neuropathological changes with storage material in swollen perikarya and a few axonal spheroids.
Noise and sensitivity analysis of harmonic radar system for vital sign detection (2013)

Harmonic radar architectures present systems of wireless detection operating at multiple harmonic carrier frequencies. The noise and sensitivity of a harmonic radar system, which is developed at 12 GHz and 24 GHz for vital signs detection, are studied numerically and experimentally. The received signal power of the radar system is analyzed numerically as a function of the distance, taking into account the radar cross section (RCS) of the patient chest. The numerical data are compared with results obtained with single carrier frequency system. The total noise is a combination of thermal noise, residual phase noise, and flicker noise that presents the most elevated factor influencing the detection at baseband. Experimental results show that with the harmonic radar, the flicker noise can be reduced by 20dB at around 1Hz baseband frequency.
Role-Attribute-Based Encryption (RABE) Access Control for Healthcare Cloud Systems (2016)

In the medical industry, it is critical to ensure the confidentiality of patientsâ€™ personal health records when storing and managing them. Before cloud computing surfaced, heath providers used local servers and hard drives to store their records and data. As cloud computing has been becoming more prominent many healthcare providers are using the cloud to store and manage their sensitive data. This journal compares and investigates two different access control models, in particular Role-Based Access Control and Attribute-Based Access Control, to validate the confidentiality of data when storing and managing personal health records on cloud services. The comparative analysis of these access control models is done to identify possible inefficiency and privacy restrictions in these two access control based models. In addition, in this journal we propose a new access control model, which we refer to as Role-Attribute-Based-Encryption Access Control (RABE), by combining some of the best aspects of both RBAC and ABAC in order to improve data privacy on cloud systems used in healthcare.
Problems on the mechanically induced polymorphic transformation (1985)

Abstract Some typical experimental results are presented and discussed phenomenologically on the topics; (i) the transformations which are readily carried out with the aid of mechanical stimulation but hardly by simple heating (PbO, ZnS); (ii) formation of metastable phases under the influence of mechanical stresses from the phase which is stable at room temperature under the atmospheric pressure (CdS, CdSe); (iii) pseudo‐equilibrium between polymorphs during grinding (CaCO 3 ).
Synthesis of Fluorinated Dialkyl Carbonates from Carbon Dioxide as a Carbonyl Source (2020)

Fluorinated dialkyl carbonates (DACs), which serve as environmentally benign phosgene substitutes, were produced successfully from carbon dioxide either directly or indirectly. Nucleophilic addition of 2,2,2-trifluoroethanol to carbon dioxide and subsequent reaction with 2,2,2-trifluoroethyltriflate (3 a) afforded bis(2,2,2-trifluoroethyl) carbonate (1) in up to 79 % yield. Additionally, carbonate 1 was obtained through the stoichiometric reaction of 3 a and cesium carbonate. Although bis(1,1,1,3,3,3-hexafluoro-2-propyl) carbonate (4) was difficult to obtain by either of the above two methods, it could be synthesized through the transesterification of carbonate 1.
60 GHz and 94 GHz antenna-coupled LiNbO/sub 3/ electrooptic modulators (1993)

Antenna-coupled LiBbO/sub 3/ electrooptic modulators can overcome the material dispersion which would otherwise prevent sensitive high-frequency operation. The authors previously demonstrated the concept with a phase modulator at X-band. They have extended this demonstration to a narrowband 60-GHz phase modulator and broadband amplitude modulator designs at 60 and 94 GHz, respectively.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
TAB Review of IEEE Consumer Electronics Magazine [Society News] (2015)

Presents the IEEE Technical Activities Board review of the IEEE Consumer Electronics Magazine.
Senotherapeutic peptide reduces skin biological age and improves skin health markers (2020)

Abstract Skin aging has been primarily related to aesthetics and beauty. Therefore, interventions have focused on reestablishing skin appearance, but not necessarily skin health, function, and resilience. Recently, cellular senescence was shown to play a role in age-related skin function deterioration and influence organismal health and, potentially, longevity. In the present study, a two-step screening was performed to identify peptides capable of reducing cellular senescence in human dermal fibroblasts (HDF) from Hutchinson-Gilford Progeria (HGPS) patients. From the top four peptides of the first round of screening, we built a 764-peptide library using amino acid scanning, of which the second screen led to the identification of peptide 14. Peptide 14 effectively decreased HDF senescence induced by HGPS, chronological aging, ultraviolet-B radiation, and etoposide treatment, without inducing significant cell death, and likely by modulating longevity and senescence pathways. We further validated the effectiveness of peptide 14 using human skin equivalents and skin biopsies, where peptide 14 promoted skin health and reduced senescent cell markers, as well as the biological age of samples, according to the Skin-Specific DNA methylation clock, MolClock. Topical application of peptide 14 outperformed Retinol treatment, the current gold-standard in “anti-aging” skin care. Finally, we determined that peptide 14 is safe for long-term applications and also significantly extends both the lifespan and healthspan of C. elegans worms tested in two independent testings. This highlights the potential for geroprotective applications of the senotherapeutic compounds identified using our screening platform beyond the skin.
Androgen receptor modulation: Lessons learned from beyond the prostate (2007)

Androgen receptor (AR) is an important transcription factor in prostatic diseases, such as prostate cancer and benign prostatic hyperplasia (BPH). AR regulates the growth and survival of both benign and cancerous prostate epithelial cells. Therefore, modulation of AR function is an important means of treating prostatic diseases. Modern pharmacotherapy for these diseases includes, for example, medical castration and AR antagonists for prostate cancer and 5-alpha-reductase inhibitors for BPH. However, these treatments have limitations and are illustrated by AR reactivation after medical castration for prostate cancer, commonly termed castrate-resistant prostate cancer. A novel method of AR modulation has been demonstrated in spinal and bulbar muscular atrophy, a disease defined by a polyglutamine repeat expansion which leads to gain-of-function changes in AR and neuromuscular pathology. Here, we examine recent findings from the description of a compound that degrades AR and induces dissociation of AR from an AR coactivator. The biochemistry of this compound may have implications for prostate cancer.
Signal processing for rapid bacterial detection (2008)

This paper proposes a methodology based on Bayesian decision theory and electrochemical impedance spectroscopy for rapid and reliable detection of Salmonella typhimurium bacteria. The proposed technique has been validated using a cost-effective and portable biosensor. Results indicate a detection time of approximately 6 minutes (5 minutes for data acquisition;1 minute for analysis) for pre-infectious bacterial concentrations. The technique has demonstrated high accuracy and can be generalized for the detection of other pathogens with healthcare relevance. Furthermore, the technique has a low computational complexity and is therefore well-suited for use in hand-held pathogen detectors.
Mechanism of the Long-Term Effects of Electromagnetic Radiation on Solutions and Suspended Colloids (1998)

The mechanisms of the electromagnetic water treatment have been studied with a multitude of techniques and it has been found that the gas/water interface is essential to perturb water and suspended colloids. Perturbation of the gas/liquid interface results in nonequilibrium conditions which require hours to relax. Certain magnetic and electric fields also produce small amounts of ozone, superoxide, hydrogen peroxide, or atomic hydrogen. The addition of hydrogen peroxide or hydrogen did not produce equivalent effects without additional gas/liquid interface perturbations with electromagnetic fields (EMFs). Hydrophobic gases such as argon or carbon dioxide which promote clathrate-like structuring of water appear to be affected more significantly through the action of EMFs.
<title>High-resolution satellite image restoration with frames</title> (1996)

The optics of satellite cameras as well as the satellite movement create a blurring effect to which is added a noise due to the electronics of the CCD captors. We introduce a deconvolution algorithm which is regularized with a hard thresholding technic, in a wavelet frame. The restoration procedure is fast and provides good metrical and perceptual results.
Posterior capsular release is a biomechanically safe procedure to perform in total knee arthroplasty (2018)

Controlled laboratory study.
Sedative Effects of Apomorphine in an Animal Model of Huntington's Disease (1979)

The sedative effectiveness of apomorphine in a newly developed animal model of Huntington's disease was examined. The motor responses of rats with kainic acid lesions of the neostriatum to a sedative dose of apomorphine (50 micrograms/kg) was similar to that observed in intact controls. In contrast, compared to controls, a marked potentiation of the motor stimulant effects of dextroamphetamine was confirmed in the kainic acid-lesioned group. We suggest that the pathological changes underlying the symptoms observed in this animal model and in Huntington's disease do not include abnormalities in presynaptic dopamine receptors in the neostriatum.
Titelbild: Open‐Pore Two‐Dimensional MFI Zeolite Nanosheets for the Fabrication of Hydrocarbon‐Isomer‐Selective Membranes on Porous Polymer Supports (Angew. Chem. 25/2016) (2016)

Piranhas haben scharfe Zähne und sind für ihren Appetit bekannt. Piranha-Lösung, eine Mischung aus Schwefelsäure und Wasserstoffperoxid, ist wiederum eines der stärksten Oxidationsmittel für die Entfernung organischer Reste; ihre Verwendung für die Detemplatisierung und Exfoliation von MFI-Nanoschichten beschreiben Q. Xiao, M. Tsapatsis et al. in der Zuschrift auf S. 7300 ff. Somit gelang die Herstellung von Kohlenwasserstoffisomer-selektiven Membranen auf einem Polymerträger. Piranhas haben scharfe Zähne und sind für ihren Appetit bekannt. Piranha-Lösung, eine Mischung aus Schwefelsäure und Wasserstoffperoxid, ist wiederum eines der stärksten Oxidationsmittel für die Entfernung organischer Reste; ihre Verwendung für die Detemplatisierung und Exfoliation von MFI-Nanoschichten beschreiben Q. Xiao, M. Tsapatsis et al. in der Zuschrift auf S. 7300 ff. Somit gelang die Herstellung von Kohlenwasserstoffisomer-selektiven Membranen auf einem Polymerträger. Nachhaltige Chemie Supramolekulare Polymerbürsten Fälschungssicherheit
Classification of genetic variants in genes associated with Lynch syndrome using a clinical history weighting algorithm (2016)

We have developed and implemented a HWA to aid in the classification of VUSs in genes associated with Lynch syndrome. The work presented here demonstrates that this HWA is able to classify MLH1, MSH2, and MSH6 VUSs as either benign or pathogenic with high accuracy.
Glenoid retroversion is an important factor for humeral head centration and the biomechanics of posterior shoulder stability (2019)

Bony alignment in terms of glenoid retroversion angle plays an important role in joint centration and posterior translation, especially in retroversion angles greater than 10°. Isolated posterior labrum repair has a significant effect on posterior translation in glenoid retroversion angles of 5° and 10°. Bony correction of glenoid version may be considered to address posterior shoulder instability with retroversion > 15°.
Heterobimetallic complexes connected by peralkylated cyclopentadienyl rings (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHeterobimetallic complexes connected by peralkylated cyclopentadienyl ringsJ. F. Buzinkai and R. R. SchrockCite this: Organometallics 1987, 6, 7, 1447–1452Publication Date (Print):July 1, 1987Publication History Published online1 May 2002Published inissue 1 July 1987https://doi.org/10.1021/om00150a014RIGHTS & PERMISSIONSArticle Views187Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (827 KB) Get e-Alerts Get e-Alerts
Proximal Tubules Have the Capacity to Regulate Uptake of Albumin (2016)

Evidence from multiple studies supports the concept that both glomerular filtration and proximal tubule (PT) reclamation affect urinary albumin excretion rate. To better understand these roles of glomerular filtration and PT uptake, we investigated these processes in two distinct animal models. In a rat model of acute exogenous albumin overload, we quantified glomerular sieving coefficients (GSC) and PT uptake of Texas Red-labeled rat serum albumin using two-photon intravital microscopy. No change in GSC was observed, but a significant decrease in PT albumin uptake was quantified. In a second model, loss of endogenous albumin was induced in rats by podocyte-specific transgenic expression of diphtheria toxin receptor. In these albumin-deficient rats, exposure to diphtheria toxin induced an increase in albumin GSC and albumin filtration, resulting in increased exposure of the PTs to endogenous albumin. In this case, PT albumin reabsorption was markedly increased. Analysis of known albumin receptors and assessment of cortical protein expression in the albumin overload model, conducted to identify potential proteins and pathways affected by acute protein overload, revealed changes in the expression levels of calreticulin, disabled homolog 2, NRF2, angiopoietin-2, and proteins involved in ATP synthesis. Taken together, these results suggest that a regulated PT cell albumin uptake system can respond rapidly to different physiologic conditions to minimize alterations in serum albumin level.
Detection of thein vivo conversion of 2-pyrrolidinone to γ-aminobutyric acid in mouse brain (1979)

Labeled gamma-aminobutyric acid was detected in mouse brain following intravenous injections of deuterium labeled 2-pyrrolidinone. [2H6]Pyrrolidinone was prepared by the reduction of [2H4]succinimide with lithium aluminum deuteride. Quantification was accomplished by a gas chromatography mass spectrometry assay method. gamma-Aminobutyric acid and internal standard, 5-aminovaleric acid, were converted to volatile derivatives by treatment with N,N-dimethylformamide dimethyl acetal. Quantitative estimates were derived from peak area measurements obtained from monitoring the parent ions of the gamma-aminobutyric acid and internal standard derivatives by repetitive scanning during the GC run. The conversion of pyrrolidinone to gamma-aminobutyric acid may provide a method for labeling central gamma-aminobutyric acid pools.
MineRL: A Large-Scale Dataset of Minecraft Demonstrations (2019)

The sample inefficiency of standard deep reinforcement learning methods precludes their application to many real-world problems. Methods which leverage human demonstrations require fewer samples but have been researched less. As demonstrated in the computer vision and natural language processing communities, large-scale datasets have the capacity to facilitate research by serving as an experimental and benchmarking platform for new methods. However, existing datasets compatible with reinforcement learning simulators do not have sufficient scale, structure, and quality to enable the further development and evaluation of methods focused on using human examples. Therefore, we introduce a comprehensive, large-scale, simulator-paired dataset of human demonstrations: MineRL. The dataset consists of over 60 million automatically annotated state-action pairs across a variety of related tasks in Minecraft, a dynamic, 3D, open-world environment. We present a novel data collection scheme which allows for the ongoing introduction of new tasks and the gathering of complete state information suitable for a variety of methods. We demonstrate the hierarchality, diversity, and scale of the MineRL dataset. Further, we show the difficulty of the Minecraft domain along with the potential of MineRL in developing techniques to solve key research challenges within it.
Magnetic and magneto-optic properties of sputtered Co/Ni multilayers (1994)

We have investigated the magnetic and magneto-optic properties of Co/Ni multilayers deposited on Ag and Au buffer layers. The samples with Au buffer layers show perpendicular magnetic anisotropy, but those with Ag buffer layers do not. The structure and degree of crystalline alignment of the buffer layer are evidently crucial to development of perpendicular magnetic anisotropy. We also present the results of polar Kerr rotation measurements as a function of wavelength and layer thickness of the multilayers.
Human capabilities of dereverberation (2000)

Humans listening to speech in a small room are frequently unaware of reverberation. It is unknown if neurological processes remove these echoes or if they are simply disregarded when speech is phonetically processed. In other words, is there a neurological mechanism that is capable of removing echoes to create a clean speech neurological signal before phonetic processing? Or is the brain capable of processing reverberant phonemes? Word intelligibility experiments examine these questions. Preliminary experiments investigate how characteristics of simulated reverberation such as room size, absorption of walls, source location, and listener position affect intelligibility. The results of these experiments are used in the design of primary experiments that address human capabilities. In the capability tests the effects of binaural listening, reverberation level, and deconvolution processing are investigated. These experiments approach the fundamental questions through the use of a three-factor experiment (the factors being binaural versus diotic, high versus low levels of reverberation, and simulated reverberation versus convolutional noise). Through the primary and interaction effects of these factors the data illustrates the extent of neurological dereverberation.
Sparse channel estimation using adaptive filtering and compressed sampling (2013)

This paper discusses the topic of estimating sparse communication channels (i.e. having mostly zero entries) using classical adaptive filtering techniques and the recently-developedmethod of compressed sampling. For this purpose, the Least-Mean Squares (LMS) a variant of it known as 10-LMS are compared with the compressed sampling technique when used to estimate a communication channels having different levels of sparsity.