gebhart/patrepeval huggingface dataset:
Poly(arylene ether)s with pendant diphenyl phosphoryl groups: Synthesis, characterization, and thermal properties (2011)

Abstract A series of poly(arylene ether)s, (PAEs), carrying a pendant diphenyl phosphoryl group were prepared via the nucleophilic aromatic substitution (NAS) reactions of 3,5‐difluorotriphenylphosphine oxide, 6 . The difluoro monomer 6 was synthesized via two‐step reaction sequence and subsequently characterized by 1 H, 13 C, 19 F, and 31 P NMR spectroscopy, GC/MS, and elemental analysis. The reactivity of the electrophilic sites in 6 , activated by only a diphenylphosphoryl group located in the meta ‐position, in 6 was probed via NMR spectroscopy and model reactions and was determined to be sufficient to undergo typical NAS reactions. High molecular weight, amorphous, organic soluble poly(arylene ether)s, bearing a pendant diphenylphosphoryl group, were prepared via the reaction of 6 with a variety of bis ‐phenols under typical NAS conditions. The poly(arylene ether)s were characterized for structure via the use of 1 H, 13 C, and 31 P NMR spectroscopy while their thermal properties were evaluated using DSC and TGA analysis. The glass transition temperatures ( T g ) of the synthesized PAEs ranged from 143 to 175 °C, while their 5% weight loss temperatures ranged from 467 to 510 °C under nitrogen and from 470 to 526 °C in air. © 2011 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2011
Dissipation Improvement of MUSCL Scheme for Computational Aeroacoustics (2001)

ABSTRACT An upwind finite-volume scheme is studied for solving the solutions of two dimensional Euler equations. It based on the MUSCL (Monotone Upstream Scheme for Conservation Laws) approach with the Roe approximate Riemann solver for the numerical flux evaluation. First, dissipation and dispersion relation, and group velocity of the scheme are derived to analyze the capability of the proposed scheme for capturing physical waves, such as acoustic, entropy, and vorticity waves. Then the scheme is greatly enhanced through a strategy on the numerical dissipation to effectively handle aeroacoustic computations. The numerical results indicate that the numerical dissipation strategy allows that the scheme simulates the continuous waves, such as sound and sine waves, at fourth-order accuracy and captures the discontinuous waves, such a shock wave, sharply as well as most of upwind schemes do. The tested problems include linear wave convection, propagation of a sine-wave packet, propagation of discontinuous and sine waves, shock and sine wave interaction, propagation of acoustic, vorticity, and density pulses in an uniform freestream, and two-dimensional traveling vortex in a low-speed freestream.
Metrology for trending alignment of the James Webb Space Telescope before and after ambient environmental testing (2017)

NASA’s James Webb Space Telescope (JWST) is a 6.6m diameter, segmented, deployable telescope for cryogenic IR space astronomy. The JWST Observatory architecture includes the Optical Telescope Element (OTE) and the Integrated Science Instrument Module (ISIM) element which contains four science instruments (SIs). Prior to integration with the spacecraft, the JWST optical assembly is put through rigorous launch condition environmental testing. This work reports on the metrology operations conducted to measure changes in subassembly alignment, including the primary mirror segments, the secondary mirror to its support structure, the tertiary mirror assembly to the backplane of the telescope and ISIM.
Effect of structure on current and potential distributions in porous electrode (1987)

Porous electrodes generally contain constricted macropores and localized micropores. The effects of the macropore constrictions on the resistance of a capillary were studied and an analytical model was developed for predicting the current distribution in a constricted macropore which directly includes constriction effects and does not require an empirical tortuosity parameter. The current and concentration distributions in localized micropores were also investigated and it was shown that the microporous area is fully accessible to charge and mass transfer processes. From these analyses it was concluded that the micropores primarily affect the kinetics of the interfacial processes by contributing to the interfacial area, while the macropores impose ohmic and mass transport limitations through the volume of the porous electrode.
Remedial Civics Education at Rutgers University (2011)

A study of the lack of remedial civics knowledge by the average Rutgers student and how that compares to the knowledge required by the federal department for every citizen
<title>Module/packaging technologies for optical components: current and future trends</title> (2001)

The basic design methodology and criteria required for packaging of optical components are reviewed, and the state-of-art of different types of the packaging technologies of laser modules and receiver modules are addressed. They are Mini-DIL DFB-LD module, wavelength-locker integrated laser module, 10 Gbps receiver module with integrated APD and preamplifier IC, and non-hermetic SMT module. Considerations on future packaging technologies and integrated optical components are also discussed.
Preoperative Reverse Transcriptase Polymerase Chain Reaction for Prostate Specific Antigen Predicts Treatment Failure Following Radical Prostatectomy (1996)

Enhanced reverse transcriptase polymerase chain reaction for PSA is a statistically significant predictor of potential failure by pathological analysis and of disease recurrence by PSA. Longer followup data are required to define further the role of the assay in the management of patients with prostate cancer.
<title>WebMARS: a multimedia search engine</title> (1999)

The Web provides a large repository of multimedia data, text, images, etc. Most current search engines focus on textural retrieval. In this paper, we focus on using an integrated textural and visual search engine for Web documents. We support query refinement which proves useful and enables cross-media browsing in addition to regular search.
Reduction of Breast Density Following Tamoxifen Treatment Evaluated by 3-D MRI. (2009)

Abstract Background: It has been reported that MRI-based density measurement is more sensitive than mammographic density to evaluate the small changes of breast density. This study analyzed the change of breast density in women receiving tamoxifen treatment using 3-D MRI.Material and Methods: Twenty-two breasts in 20 women were studied. Two MRI studies were performed at 1.5T, the baseline scan acquired after surgery and prior to receiving tamoxifen, and the follow-up scan at 10 months to 30 months after tamoxifen treatment. Non-fat-suppression T1-weighted images were used for the density measurement. The breast and the fibroglandular tissue were segmented using a computer-assisted algorithm recently published by our group. For each breast, the total fibroglandular tissue volume and the total breast volume were calculated, and then the ratio was calculated as the percent breast density (%BD). The changes in breast volume, fibroglandular tissue volume, and the percent density in the F/U scan compared to the B/L scan were evaluated. The reduction in the fibroglandular volume (ΔFV=FV2-FV1, ml), and in the percent breast density (Δ%BD= %BD2-%BD1) were analyzed.Results: The total breast volume did not show significant changes between F/U and B/L. For analysis of fibroglandular volume, 20 breasts showed volume reduction and 2 showed slight increase of volume. Overall, the mean ΔFV was 20.7ml, with 33% reduction. The ΔFV was correlated with the baseline FV (r=0.82) (Figure 1), indicating that when the fibroglandular tissue volume was higher, more reduction was found.For analysis of %BD, 19 breasts showed reduction, and 3 showed increased density, with a mean Δ%BD of 4.7%. The 22 breasts were further divided into three categories based on their B/L density as: fatty breast (%BD&amp;lt; 8%, N=4), moderately dense breast (%BD 8-20%, N=9), and dense breast (%BD &amp;gt;20%, N=9). The amount of density reduction was associated with the B/L density, showing 10.9, 17.2, and 28.6 ml for ΔFV; and 1.2%, 3.9%, and 7.2% for Δ%BD respectively in these 3 groups. Statistically, only Δ%BD between the fatty and the dense groups showed a significant difference (P=0.02).Discussion: MRI provides strong soft tissue contrast, thus it may have advantages for revealing detailed density distribution compared to mammography. The %BD can be measured by normalizing the FV to the total breast volume, analogous to the mammographic density. However, this will be subjective to the variations in the measurement of breast volume. The FV within the breast was a more robust parameter, which showed reduction in 20 of 22 breasts with a mean reduction of 33%, also a significant correlation with B/L FV. The reduction of density is expected to be through decreased hormonal level in the breast, and the reduction of fibroglandular tissue density should be correlated with the baseline density. Our results are consistent with this expectation, and demonstrate that MRI can be used to evaluate the density change induced by tamoxifen. Citation Information: Cancer Res 2009;69(24 Suppl):Abstract nr 4021.
Performance Evaluation of the T6 Ion Engine (2010)

*† * ‡ § ** The T6 ion engine is a 22-cm diameter, 4.5-kW Kaufman-type ion thruster produced by QinetiQ, Ltd., and is baselined for the European Space Agency BepiColombo mission to Mercury and is being qualified under ESA sponsorship for the extended range AlphaBus communications satellite platform. The heritage of the T6 includes the T5 ion thruster now successfully operating on the ESA GOCE spacecraft. As a part of the T6 development program, an engineering model thruster was subjected to a suite of performance tests and plume diagnostics at the Jet Propulsion Laboratory. The engine was mounted on a thrust stand and operated over its nominal throttle range of 2.5 to 4.5 kW. In addition to the typical electrical and flow measurements, an EB mass analyzer, scanning Faraday probe, thrust vector probe, and several near-field probes were utilized. Thrust, beam divergence, double ion content, and thrust vector movement were all measured at four separate throttle points. The engine performance agreed well with published data on this thruster. At full power the T6 produced 143 mN of thrust at a specific impulse of 4120 seconds and an efficiency of 64%; optimization of the neutralizer for lower flow rates increased the specific impulse to 4300 seconds and the efficiency to nearly 66%. Measured beam divergence was less than, and double ion content was greater than, the ring-cusp-design NSTAR thruster that has flown on NASA missions. The measured thrust vector offset depended slightly on throttle level and was found to increase with time as the thruster approached thermal equilibrium.
ChemInform Abstract: Reductive Cyclization of Ketones Tethered to Activated Olefins Mediated by Magnesium in Methanol. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Reduction of Scratch on Brush Scrubbing in Post CMP Cleaning by Analyzing Contact Kinetics on Ultra Low-k Dielectric (2009)

Damage reduction during planarization is strongly required to avoid scratch generation leading to yield loss in an integrated circuit fabrication especially after implementation of ultra low-k dielectrics in Cu damascene structure. By analyzing contact characteristic on the advanced non-porous ultra low-k dielectric, fluorocarbon film, brush scrubbing at high rotation rate and low down pressure is proposed to satisfy both particle removal efficiency and scratch reduction in post CMP cleaning. Shear force increases with increasing in brush rotation rate because of enlargement of pressured area which is generated by fluid flow. Enhancement of contribution of fluid flow by increasing brush rotation rate with lowering down force to particle removable efficiency can be direction for future low-k compatible process.
RecombinantOchrobactrum anthropiExpressingBrucella abortusCu,Zn Superoxide Dismutase Protects Mice againstB. abortusInfection Only after Switching of Immune Responses to Th1 Type (2002)

The members of the genus Brucella are gram-negative, facultatively intracellular bacterial pathogens that cause brucellosis in many animal species and humans. Although live, attenuated vaccines are available to protect several animal species from the disease, there is no safe and effective vaccine for human use. Here we report that a bacterium that is closely related to Brucella species, Ochrobactrum anthropi, can be used as a vaccine vector for the delivery of Brucella antigens to mice, leading to the elicitation of protective immunity against brucellosis. Brucella abortus Cu,Zn superoxide dismutase (SOD), a protective Brucella antigen, was expressed in large amounts in O. anthropi strain 49237 by use of the broad-host-range plasmid pBBR1MCS. Neither O. anthropi strain 49237 nor the recombinant O. anthropi strain 49237SOD, expressing B. abortus Cu,Zn SOD, provided protection against virulent Brucella infection in mice. Analysis of immune responses indicated that strains 49237 and 49237SOD stimulated a mix of Th1 and Th2 type responses in the mice. After the immune response was switched to a Th1-biased response by addition of oligonucleotides containing unmethylated CpG motifs, both O. anthropi strain 49237 and the recombinant O. anthropi strain 49237SOD induced protection in mice. However, the protection conferred by strain 49237SOD was significantly better than that induced by the parental strain, 49237.
AutoMoDe - Model-Based Development of Automotive Software (2005)

The paper describes first results from the AutoMoDe (automotive model-based development) project. The project's overall goal is to develop an integrated methodology for model-based development of automotive control software, based on problem-specific design notations with an explicit formal foundation. Based on the existing AutoFOCUS framework (Huber, F. et al., 1997), a tool prototype is being developed in order to illustrate and validate the key elements of our approach.
Two frequent loss‐of‐function mutations in Aurora Kinase C gene in Algerian infertile men with macrozoospermia (2020)

Macrozoospermia is associated with severe male infertility. To date, the only gene implicated in this phenotype is the Aurora Kinase C gene. We report in this work the genetic screening of AURKC mutations in 34 patients with macrozoospermia among 3,536 Algerian infertile men. Nineteen patients (56%) were homozygotes for the c.144delC mutation, eight (23.52%) homozygotes for the c.744C>G (p.Y248*) mutation and two (5.88%) compound heterozygotes. No AURKC mutation was identified in five patients (14.7%). Interestingly and although it is generally accepted that nearly all positive mutated AURKC patients have close to 100% large-head spermatozoa, our results showed that 11 patients with AURKC mutations (32.35%) had large-headed spermatozoa lower than 70% (7 with c.144delC and 4 with p.Y248*), and no mutation was found in 2 patients who had >70% of macrocephalic spermatozoa. Twenty ICSI attempts were performed before genetic screening resulting in 39 embryos but no pregnancy was obtained. The sequencing of AURKC exons 3 and 6 is appropriate as a first-line genetic exploration in these patients to avoid unsuccessful ICSI attempts. A percentage of large head spermatozoa beyond 25% and a percentage of multiflagellar spermatozoa beyond 10% are predictive of a positive mutation diagnosis.
Evidence That Some Breast Implant Associated Anaplastic Large Cell Lymphomas Arise in the Context of Allergic Inflammation (2017)

Abstract Breast Implant Associated Large Cell Lymphoma (BIA-ALCL) is a recently recognized lymphoma found surrounding breast implants of more than 380 women worldwide. The etiology of BIA-ALCL is unknown although a bacterial biofilm overlying BIA-ALCL associated implants has been demonstrated. Here we provide evidence that BIA-ALCL may be mediated by chronic allergic inflammation in a group of BIA-ALCL patients. We studied 3 BIA-ALCL lines (TLBR-1/2/3), seroma fluids and/or resected capsular tissues of 14 patients with BIA-ALCL. Resected capsules revealed chronic inflammation including fibrosis, plasma cells, lymphocytes, primary and secondary lymphoid follicles, mast cells and eosinophils. IL-13, the signature cytokine of allergic inflammation, was secreted by BIA-ALCL lines and localized to small lymphocytes and anaplastic cells in most clinical samples. Th2 transcription factor GATA3 co-localized to anaplastic cells producing IL-13. IL-13 is known to induce Ig class switch of B cells to produce IgE. Accordingly, IgE was detected bound to follicular dendritic antigen presenting cells in lymphoid follicles in 3 cases and mast cells in 5 cases. As a likely source of IgE, plasma cells staining for IgE were found in capsular tissues and regional lymph nodes. Activated mast cells produce prostaglandin D2 (PGD2). The receptor for PGD2, CRTH2, was expressed by each of 3 BIA-ALCL lines and anaplastic cells in 5 of 6 clinical samples analyzed. Ligands that activate CRTH2 stimulate chemotaxis (i.e. directed migration) of leukocytes active in mediating allergic responses, viz., eosinophils, basophils, and Th2 cells. Not unexpectedly, eosinophils were found surrounding anaplastic cells in 4 of 5 cases with IgE observed on mast cells. In contrast, only few scattered tissue and intravascular eosinophils were present in 1 of 15 benign capsules. Together, these findings suggest that some BIA-ALCL are associated with a chronic allergic immune response to as yet undefined antigen(s). Disclosures Kadin: Allergan, Inc: Honoraria. Glicksman: Allergan, Inc: Honoraria.
The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer (2017)

Quorum sensing (QS) is a bacterial cell-to-cell communication process that relies on the production, release, and response to extracellular signaling molecules called autoinducers. QS controls virulence and biofilm formation in the human pathogen Pseudomonas aeruginosa. P. aeruginosa possesses two canonical LuxI/R-type QS systems, LasI/R and RhlI/R, which produce and detect 3OC12-homoserine lactone and C4-homoserine lactone, respectively. Here, we use biofilm analyses, reporter assays, RNA-seq studies, and animal infection assays to show that RhlR directs both RhlI-dependent and RhlI-independent regulons. In the absence of RhlI, RhlR controls the expression of genes required for biofilm formation as well as genes encoding virulence factors. Consistent with these findings, ΔrhlR and ΔrhlI mutants have radically different biofilm phenotypes and the ΔrhlI mutant displays full virulence in animals whereas the ΔrhlR mutant is attenuated. The ΔrhlI mutant cell-free culture fluids contain an activity that stimulates RhlR-dependent gene expression. We propose a model in which RhlR responds to an alternative ligand, in addition to its canonical C4-homoserine lactone autoinducer. This alternate ligand promotes a RhlR-dependent transcriptional program in the absence of RhlI.
Beta B1-Crystallin: Identification of a Candidate Ciliary Body Uveitis Antigen (2003)

This study identified betaB1-crystallin as a new cytoplasmic ciliary body antigenic target of a marker autoantibody associated with uveitis. This characterization of betaB1-crystallin outside the lens raises questions about its extralenticular expression, intracellular role, and potential target of inflammation in uveitis.
New organoselenium methodology (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew organoselenium methodologyDennis LiottaCite this: Acc. Chem. Res. 1984, 17, 1, 28–34Publication Date (Print):January 1, 1984Publication History Published online1 May 2002Published inissue 1 January 1984https://pubs.acs.org/doi/10.1021/ar00097a005https://doi.org/10.1021/ar00097a005research-articleACS PublicationsRequest reuse permissionsArticle Views677Altmetric-Citations161LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Oral Direct Thrombin Inhibitor Ximelagatran Compared with Warfarin for the Prevention of Venous Thromboembolism After Total Knee Arthroplasty (2006)

Colwell, Clifford W. Jr. MD; Berkowitz, Scott D. MD; Lieberman, Jay R. MD; Comp, Philip C. MD; Ginsberg, Jeffrey S. MD; Paiement, Guy MD; McElhattan, Jennifer MS; Roth, Anne W. MS; Francis, Charles W. MD Author Information
A Hamilton-Jacobi Equation for Evaluating EEMI Propagation in a Computing System (2019)

In this paper, we present a theoretical framework for modeling the empirically observed cascading of software failures on a complicated computing system exposed to extreme electromagnetic interference (EEMI). Our approach is to treat the temporal evolution of the electromagnetic coupling and the resultant cascading series of electromagnetic-induced faults as the “flow” in a dynamic fluid-mechanical system and thereby utilize aspects of the Navier Stokes and Hamilton-Jacobi equations to predict the rate of this flow. Therefore, inspired by the concepts of fluid dynamics [1], we include a diffusion term in the Hamilton-Jacobi-Isaacs (HJI) equation. We have considered two approaches. In one we apply a Taylor expansion to the optimality principle and consider additional terms; in the other scenario, we simply add a diffusion term in the form of a Laplacian applied to the cost function H(x,...) and some constant c, as it is present in the Navier-Stokes equation for incompressible flow. We provide numerical comparisons for both approaches with respect to the original HJI equation where the dynamical vector field corresponds to analytical models of a NOR logic gate. This model is a second-order differential equation that describes the behavior of the gate that incorporates a new term accounting for EEMI injection.
On-Chip Kerr Broadening of an Electro-Optic Pulse Source on thin-film lithium niobate (2021)

We realize resonant Kerr broadening of an integrated-electro-optic-modulator-based femtosecond pulse source using a high- Q 30-GHz microresonator on thin-film lithium niobate. A frequency comb spectrum spanning over 100 nm is generated using 16 mW average on-chip power and 0.53 pJ pulse energy.