gebhart/patrepeval huggingface dataset:
Phase compositions, viscosities, and densities for aqueous two-phase systems composed of polyethylene glycol and various salts at 25 .degree.C (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhase compositions, viscosities, and densities for aqueous two-phase systems composed of polyethylene glycol and various salts at 25 .degree.CSteven M. Snyder, Kenneth D. Cole, and David C. SzlagCite this: J. Chem. Eng. Data 1992, 37, 2, 268–274Publication Date (Print):April 1, 1992Publication History Published online1 May 2002Published inissue 1 April 1992https://pubs.acs.org/doi/10.1021/je00006a036https://doi.org/10.1021/je00006a036research-articleACS PublicationsRequest reuse permissionsArticle Views1252Altmetric-Citations129LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Morphology of the Pelvic Limb Skeleton in Jaguar (Panthera Onca) (2012)

The jaguar is one of the biggest cats in South and Central America. It has a morphology similar tothat of the leopard, which is why we tried to establish the anatomical characteristics of its limb bones, fromwhich it is possible to do morphological and functional assessments. The study materials consisted of thebones of a male jaguar (Panthera onca) with melanism which had been donated for teaching purposes by theZoological Garden in Bucharest. Whereas it is a rare species, we describe in detail its limb bonemorphology, in order to complete the existing data in the literature.
Molecular Weight Effects on Poly(arylene ether sulfone)-Based Random and Multiblock Copolymers Characteristics for Fuel Cells (2010)

The commercialization of proton exchange membrane (PEM) fuel cells depends largely upon the development of PEMs whose properties are enhanced over current perfluorinated sulfonic acid PEMs. Understanding how a PEM’s molecular weight and morphology affect its relevant performance properties is essential to this effort. Changes in molecular weight were found to have little effect on the phase separated morphologies, water uptake, and proton conductivities of random copolymers. Changes in block length, however, have a pronounced effect on multiblock copolymers, affecting surface and bulk morphologies, water uptake, proton conductivity, and hydrolytic stability, suggesting that multiblock copolymer PEM properties may be optimized by changes in morphology.
Multihop Routing in Hybrid Vehicle-to-Vehicle and Vehicle-to-Infrastructure Networks (2018)

Efficient data delivery is of significant importance, however highly challenging for vehicle-to-vehicle (V2V) communications due to high vehicle speed, time-varying vehicle density, and limited inter-vehicle contact duration. Alternatively, incorporating vehicle-to-infrastructure (V2I) communications paves a migration path for bridging long-range vehicular connectivity by introducing stationary network entities, e.g., road-side unit. In this paper, we develop a mathematical framework to address the performance of data delivery in hybrid V2V and V2I networks by considering both latency and throughput requirements. With the theoretical analysis, we formulate an optimization problem to maximize the weighted sum of the latency and the throughput for the hybrid V2V and V2I networks, and further propose a multihop routing algorithm to select the optimal route for the weighted sum maximization. Simulation results show that the proposed solution achieves significantly higher throughput and lower latency compared to the existing routing algorithms.
Qualification of National Cancer Institute–Designated Cancer Centers for Quantitative PET/CT Imaging in Clinical Trials (2017)

The National Cancer Institute developed the Centers for Quantitative Imaging Excellence (CQIE) initiative in 2010 to prequalify imaging facilities at all of the National Cancer Institute-designated comprehensive and clinical cancer centers for oncology trials using advanced imaging techniques, including PET. Here we review the CQIE PET/CT scanner qualification process and results in detail. <b>Methods:</b> Over a period of approximately 5 y, sites were requested to submit a variety of phantoms, including uniform and American College of Radiology-approved phantoms, PET/CT images, and examples of clinical images. Submissions were divided into 3 distinct time periods: initial submission (T0) and 2 requalification submissions (T1 and T2). Images were analyzed using standardized procedures, and scanners received a pass or fail designation. Sites had the opportunity to submit new data for scanners that failed. Quantitative results were compared across scanners within a given time period and across time periods for a given scanner. <b>Results:</b> Data from 65 unique PET/CT scanners across 56 sites were submitted for CQIE T0 qualification; 64 scanners passed the qualification. Data from 44 (68%) of those 65 scanners were submitted for T2. From T0 to T2, the percentage of scanners passing the CQIE qualification on the first attempt rose from 38% for T1 to 67% for T2. The most common reasons for failure were SUV outside specifications, incomplete submission, and uniformity issues. Uniform phantom and American College of Radiology-approved phantom results between scanner manufacturers were similar. <b>Conclusion:</b> The results of the CQIE process showed that periodic requalification may decrease the frequency of deficient data submissions. The CQIE project also highlighted the concern within imaging facilities about the burden of maintaining different qualifications and accreditations. Finally, for quantitative imaging-based trials, further evaluation of the relationships between the level of the qualification (e.g., bias or precision) and the quality of the image data, accrual rates, and study power is needed.
Detection of local and long‐path VLF/ELF radiation from modulated ionospheric current systems (1985)

This paper describes the local and long‐path very low frequency/extremely low frequency (VLF/ELF) radiation produced by modulation of the ionospheric current systems during high frequency (HF) heating of the ionospheric D region and very high frequency (VHF) heating of the equatorial electrojet. A brief description of the theory and the geometry of the heating experiment is followed by a discussion of local VLF/ELF radiation detected near the HF transmitter locations at Arecibo, Puerto Rico, and at the Jicamarca Radar Observatory near Lima, Peru. Long‐path detection of VLF/ELF radiation initially recorded on a path from Tromso, Norway, to the Pennsylvania State University in 1981 is updated with current experimental long‐path results over paths between Jicamarca, Peru, and Salinas, Puerto Rico, as well as Arecibo, Puerto Rico, to the Pennsylvania State University.
Stability of DNA Triplexes on Shuttle Vector Plasmids in the Replication Pool in Mammalian Cells (2000)

Triple helix-forming oligonucleotides may be useful as gene-targeting reagents in vivo, for applications such as gene knockout. One important property of these complexes is their often remarkable stability, as demonstrated in solution and in cells following transfection. Although encouraging, these measurements do not necessarily report triplex stability in cellular compartments that support DNA functions such as replication and mutagenesis. We have devised a shuttle vector plasmid assay that reports the stability of triplexes on DNA that undergoes replication and mutagenesis. The assay is based on plasmids with novel variant supF tRNA genes containing embedded sequences for triplex formation and psoralen cross-linking. Triple helix-forming oligonucleotides were linked to psoralen and used to form triplexes on the plasmids. At various times after introduction into cells, the psoralen was activated by exposure to long wave ultraviolet light (UVA). After time for replication and mutagenesis, progeny plasmids were recovered and the frequency of plasmids with mutations in the supF gene determined. Site-specific mutagenesis by psoralen cross-links was dependent on precise placement of the psoralen by the triple helix-forming oligonucleotide at the time of UVA treatment. The results indicated that both pyrimidine and purine motif triplexes were much less stable on replicated DNA than on DNA in vitro or in total transfected DNA. Incubation of cells with amidoanthraquinone-based triplex stabilizing compounds enhanced the stability of the pyrimidine triplex.
A soluble activin Type IIA receptor induces bone formation and improves skeletal integrity (2008)

Diseases that affect the regulation of bone turnover can lead to skeletal fragility and increased fracture risk. Members of the TGF-beta superfamily have been shown to be involved in the regulation of bone mass. Activin A, a TGF-beta signaling ligand, is present at high levels in bone and may play a role in the regulation of bone metabolism. Here we demonstrate that pharmacological blockade of ligand signaling through the high affinity receptor for activin, type II activin receptor (ActRIIA), by administration of the soluble extracellular domain of ActRIIA fused to a murine IgG2a-Fc, increases bone formation, bone mass, and bone strength in normal mice and in ovariectomized mice with established bone loss. These observations support the development of this pharmacological strategy for the treatment of diseases with skeletal fragility.
Resposta imune humoral na paracoccidioidomicose experimental em camundongos ddY (2007)

A paracoccidioidomicose (PCM) é uma micose sistêmica, restrita à América Latina, com maior incidência no Brasil. O camundongo ddY tem sido empregado como modelo murino de PCM e, no entanto, não há informações a respeito da resposta imune desse animal frente à infecção. O presente estudo tem como objetivo avaliar a resposta imune humoral específica para o principal antígeno, gp43, do fungo Paracoccidioides brasiliensis , em camundongos ddY infectados com a cepa virulenta Pb 18. Foram realizadas análises da antigenemia e histopatológico em vários órgãos e em diferentes tempos pós-infecção. Os resultados obtidos demonstraram aumento nos níveis de IgG anti-gp43 nos dias 14, 17, 21, 24, 28 e 56 pós-infecção e aumento no nível de gp43 solúvel aos 28 dias pós-infecção. As células fúngicas foram detectadas em todos os órgãos analisados (cérebro, coração, pulmão, fígado, baço e rim) e em todos os períodos. As lesões granulomatosas tornaramse predominantes 14 dias pós-infecção. Os resultados evidenciaram que o camundongo ddY produz resposta imune humoral frente ao principal antígeno de P. brasiliensis , apresentando-se elevado até 56 dias pósinfecção. A redução do nível de gp43 solúvel na fase crônica, supostamente devido ao início do controle da infecção, requer estudos complementares adicionais.
Determination of glycosylation sites in O‐linked glycopeptides: A sensitive mass spectrometric protocol (1993)

Abstract A sensitive mass spectrometric method for the specific identification of O ‐glycosylation sites in glycopeptides is presented. Reductive β‐elimination liberates a peptide containing a specifically modified amino acid at the former site of carbohydrate attachment. Mass spectrometry is used to determine the sequence of the modified peptide, in which the position of the modified amino acid marks the site of O ‐glycosylation. The method also provides information on the carbohydrate chain and is applicable at the low nanomolar level.
Stereochemical studies of simple cyclooctyl systems (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereochemical studies of simple cyclooctyl systemsStuart L. Schreiber, David B. Smith, and Gayle SchulteCite this: J. Org. Chem. 1989, 54, 25, 5994–5996Publication Date (Print):December 1, 1989Publication History Published online1 May 2002Published inissue 1 December 1989https://pubs.acs.org/doi/10.1021/jo00286a039https://doi.org/10.1021/jo00286a039research-articleACS PublicationsRequest reuse permissionsArticle Views406Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Triggered Receivers for Optoelectronic-VLSI (1999)

We describe a "triggered" transimpedance receiver- usable in noisy environments typical of dense OEVLSI chips that combine analog optoelectronic I/O with high-density digital logic. Measured data from such receiver show enhanced immunity to supply variations compared to a conventional transimpedance receiver.
Nanoscale electromechanical properties of template-assisted hierarchical self-assembled cellulose nanofibers (2018)

Cellulose, a major constituent of our natural environment and a structured biodegradable biopolymer, has been shown to exhibit shear piezoelectricity with potential applications in energy harvesters, biomedical sensors, electro-active displays and actuators. In this regard, a high-aspect ratio nanofiber geometry is particularly attractive as flexing or bending will likely produce a larger piezoelectric response as compared to axial deformation in this material. Here we report self-assembled cellulose nanofibers (SA-CNFs) fabricated using a template-wetting process, whereby parent cellulose nanocrystals (CNCs) introduced into a nanoporous template assemble to form rod-like cellulose clusters, which then assemble into SA-CNFs. Annealed SA-CNFs were found to exhibit an anisotropic shear piezoelectric response as directly measured using non-destructive piezo-response force microscopy (ND-PFM). We interpret these results in light of the distinct hierarchical structure in our template-grown SA-CNFs as revealed by scanning electron microscopy (SEM) and high resolution transmission electron microscopy (TEM).
Two's a crowd: improving speaker diarization by automatically identifying and excluding overlapped speech (2008)

We present an update to our initial work [1] on overlapped speech detection for improving speaker diarization. Specifically, we describe the addition of new features and feature warping techniques that improve segmenter and, consequently, diarization performance. We also demonstrate improved diarization performance by additionally using overlap segment information in a new diarization pre-processing step which excludes overlap segments from speaker clustering. On a subset of the AMI Meeting Corpus we show that this overlap exclusion step nearly triples the relative improvement of diarization error rate as compared to overlap segment post-processing alone. Index Terms: speaker diarization, overlap detection
Raman scattering probe of anharmonic effects in NiSi (2004)

Abstract We report a systematic temperature‐dependent Raman scattering study of NiSi thin films. In agreement with the basic anharmonic theory, the strong Raman peak from NiSi at about 214 cm −1 shows phonon softening and broadening with an increase in the sample temperature. Comparative study of the temperature dependence of this first‐order Raman peak from NiSi powder and the film show that NiSi layers of thickness 15–90 nm are under tensile thermal stress. The results also show that the total phonon shift observed in the temperature range 80–500 K is independent of the silicide film thickness. We have also shown that Raman spectroscopy is a faster and more sensitive technique than x‐ray diffraction for phase identification in NiSi nanolayers, hence Raman scattering can be used as a valuable tool for in situ growth and process monitoring of nickel silicides. Copyright © 2004 John Wiley &amp; Sons, Ltd.
Force Regulation in Multiple Manipulator Systems (1993)

An important advantage of multiple manipulator systems is the possibility to regulate the internal force in the payload. Common force control strategies include impedance control, position accommodation force control and Jacobian force control. This paper mainly considers the latter two schemes for which detailed dynamic models for the arms and the environment are not required. Comparison between these two methods are made and some experimental results on decentralized position accommodation force control are discussed.
In Vitro Cellular Adaptations of Indicators of Longevity in Response to Treatment with Serum Collected from Humans on Calorie Restricted Diets (2008)

Calorie restriction (CR) produces several health benefits and increases lifespan in many species. Studies suggest that alternate-day fasting (ADF) and exercise can also provide these benefits. Whether CR results in lifespan extension in humans is not known and a direct investigation is not feasible. However, phenotypes observed in CR animals when compared to ad libitum fed (AL) animals, including increased stress resistance and changes in protein expression, can be simulated in cells cultured with media supplemented with blood serum from CR and AL animals. Two pilot studies were undertaken to examine the effects of ADF and CR on indicators of health and longevity in humans. In this study, we used sera collected from those studies to culture human hepatoma cells and assessed the effects on growth, stress resistance and gene expression. Cells cultured in serum collected at the end of the dieting period were compared to cells cultured in serum collected at baseline (before the dieting period). Cells cultured in serum from ADF participants, showed a 20% increase in Sirt1 protein which correlated with reduced triglyceride levels. ADF serum also induced a 9% decrease in proliferation and a 25% increase in heat resistance. Cells cultured in serum from CR participants induced an increase in Sirt1 protein levels by 17% and a 30% increase in PGC-1alpha mRNA levels. This first in vitro study utilizing human serum to examine effects on markers of health and longevity in cultured cells resulted in increased stress resistance and an up-regulation of genes proposed to be indicators of increased longevity. The use of this in vitro technique may be helpful for predicting the potential of CR, ADF and other dietary manipulations to affect markers of longevity in humans.
Tracking Targeted Bimodal Nanovaccines: Immune Responses and Routing in Cells, Tissue, and Whole Organism (2014)

Dendritic cells (DCs) are the most potent antigen-presenting cells (APCs), involved in the induction of immunity and currently exploited for antitumor immunotherapies. An optimized noninvasive imaging modality capable of determining and quantifying DC-targeted nanoparticle (NP) trajectories could provide valuable information regarding therapeutic vaccine outcome. Here, targeted poly(d,l-lactide-co-glycolide) nanoparticles (PLGA NPs) recognizing DC receptors were equipped with superparamagnetic iron oxide particles (SPIO) or gold nanoparticles with fluorescently labeled antigen. The fluorescent label allowed for rapid analysis and quantification of DC-specific uptake of targeted PLGA NPs in comparison to uptake by other cells. Transmission electron microscopy (TEM) showed that a fraction of the encapsulated antigen reached the lysosomal compartment of DCs, where SPIO and gold were already partially released. However, part of the PLGA NPs localized within the cytoplasm, as confirmed by confocal microscopy. DCs targeted with NPs carrying SPIO or fluorescent antigen were detected within lymph nodes as early as 1 h after injection by magnetic resonance imaging (MRI). Despite the fact that targeting did not markedly affect PLGA NP biodistribution on organism and tissue level, it increased delivery of NPs to DCs residing in peripheral lymph nodes and resulted in enhanced T cell proliferation. In conclusion, two imaging agents within a single carrier allows tracking of targeted PLGA NPs at the subcellular, cellular, and organismal levels, thereby facilitating the rational design of in vivo targeted vaccination strategies.
ChemInform Abstract: INTRAMOLECULAR AZIDE CYCLOADDITION (IAC) REACTIONS IN THE INDOLE SERIES. AN APPROACH TO CLAVICIPITIC ACID (1982)

Abstract Aus 4‐Formy1‐indo1 (I) und (II) erhält man nach Wittig ein Olefin (11121), das zur Mannichbase (IIIb) kondensiert und dann weiter mit Malonsäureester und Chlorkohlensäureester zu (IV) kondensiert und substituiert werden kann.
Selective Monoarylation of Primary Anilines Catalyzed by Pd(dippf) and its Application in OLED Component Synthesis (2016)

Abstract Palladium 1,1′‐bis(diisopropylphosphino)‐ferrocene [Pd(dippf)] complexes were found to promote the monoarylation of primary anilines with unprecedented selectivities. They also allow the sequential arylation of primary anilines with two different aryl bromides in one pot. The reactions can be performed at low catalyst loadings (0.2 mol%) and high substrate concentrations. The synthetic utility of the optimum catalyst was demonstrated by the synthesis of various di‐ and triarylamines. A particular focus was set on compounds with carbazole and fluorene moieties as employed in state‐of‐the‐art small‐molecule organic light emitting diodes (OLEDs). magnified image
Conducted noise prediction for zero-crossing issue in totem-pole bridgeless PFC converter (2017)

This paper focuses on zero-crossing spike current issue in totem-pole bridgeless PFC converter. Spike current occurs at every input voltage zero-crossing and becomes a severe conducted common mode noise source. The zero-crossing issue is discussed by theoretical analysis and mathematical calculation, the conducted noise caused by zero-crossing issue can be predicted by calculating Fourier coefficient of approximate spike current waveform. Based on the analysis, a noise reduction method is proposed to solve zero-crossing issue. Finally, the experiments are achieved on a GaN-based totem-pole bridgeless PFC converter and show that the common mode conducted noise caused by spike current can by reduced effectively.