gebhart/patrepeval huggingface dataset:
Complex modulated critically sampled filter banks based on cosine and sine modulation (2003)

This paper explores subband processing of complex (I/Q) signals which finds various important applications especially in communications signal processing. Instead of using traditional DFT based systems, the filter bank based systems are very interesting choices when high selectivity in the subchannels is required. We present a novel efficient complex modulated critically sampled filter bank structure which is based on a combination of cosine and sine modulated filter banks. We show that in case of critically sampled analysis-synthesis filter bank system with complex input signal and highly selective channel filters, perfect reconstruction can be achieved only if the low-rate subchannel signals are real.
Synthesis of Stable Thiazole-Linked Covalent Organic Frameworks via a Multicomponent Reaction (2020)

The development of robust synthetic routes to stable covalent organic frameworks (COFs) is important to broaden the range of applications for these materials. We report here a simple and efficient three-component assembly reaction between readily available aldehydes, amines, and elemental sulfur via a C-H functionalization and oxidative annulation under transition-metal-free conditions. Five thiazole-linked COFs (TZ-COFs) were synthesized using this method. These materials showed high levels of crystallinity, high specific surface areas, and excellent physicochemical stability. The photocatalytic applications of TZ-COFs were investigated, and <b>TZ-COF-4</b> gave high sacrificial hydrogen evolution rates from water (up to 4296 μmol h<sup>-1</sup> g<sup>-1</sup> under visible light irradiation) coupled with high stability and recyclability, with sustained hydrogen evolution for 50 h.
Internal Short Circuit Trigger Method for Lithium-Ion Battery Based on Shape Memory Alloy (2017)

Internal short circuit (ISCr) is one of the major safety issues of lithium batteries and would lead to thermal runaway of batteries. Repeating ISCr in laboratory requires to create small-scale short circuit inside integrated batteries, which is very hard for existed safety test methods. In this paper, a novel ISCr trigger method based on shape memory effect of shape memory alloy (SMA) is proposed, which is easy to be implanted into batteries while has minor influences on batteries normal performance. The proposed SMA ISCr trigger method is employed to conduct ISCr experiments, including the severest type of ISCr, the Aluminum-Anode ISCr, and the most common type of ISCr, the Cathode-Anode ISCr. The experiments results show that the Aluminum-Anode ISCr leads to explosion while the Cathode-Anode ISCr only leads to mild self-discharging. Compared with the nail penetration test, the proposed SMA ISCr trigger method in the Aluminum-Anode ISCr experiment has 1) better consistency, given that all of the 4 tested batteries have their maximum temperature in the range of 383∼393°C; 2) better reliability in evaluating battery safety properties, given that all of the 4 tested batteries have the repeatable explosion behavior. The relative ease of inserting this controllable SMA ISCr and the repeatability of the produced data can lead to better modeling and detection techniques of battery internal shorts such as plating and dendrite formation.
MgF2 nanoparticle-coated teeth inhibit Streptococcus mutans biofilm formation on a tooth model (2013)

The formation of biofilms on tooth surfaces, called dental plaque, is a prerequisite for the development of both dental caries and periodontal disease. Streptococcus mutans plays an important role in the development of dental caries. Fluoride is routinely used to protect teeth against decay. In the current study, we examined whether we can use a sonochemical based method to coat artificial teeth with MgF<sub>2</sub> nanoparticles (NPs). The results showed that the artificial tooth surface was homogenously and evenly covered with an MgF<sub>2</sub> NP layer and successful in inhibiting S. mutans biofilm formation by over 60%. This antibiofilm activity was also present following incubation with saliva. The activity was dependent on the nano-crystalline characteristics of the material as fluoride ions could induce a similar reduction in biofilm formation. Taken together, our results indicate that the surface modification of artificial teeth with MgF<sub>2</sub> NPs can be effective in preventing the S. mutans biofilm.
Petri-plate, bacteria, and laser optical scattering sensor (2022)

Classical microbiology has paved the path forward for the development of modern biotechnology and microbial biosensing platforms. Microbial culturing and isolation using the Petri plate revolutionized the field of microbiology. In 1887, Julius Richard Petri invented possibly the most important tool in microbiology, the Petri plate, which continues to have a profound impact not only on reliably isolating, identifying, and studying microorganisms but also manipulating a microbe to study gene expression, virulence properties, antibiotic resistance, and production of drugs, enzymes, and foods. Before the recent advances in gene sequencing, microbial identification for diagnosis relied upon the hierarchal testing of a pure culture isolate. Direct detection and identification of isolated bacterial colonies on a Petri plate with a sensing device has the potential for revolutionizing further development in microbiology including gene sequencing, pathogenicity study, antibiotic susceptibility testing , and for characterizing industrially beneficial traits. An optical scattering sensor designated BARDOT (bacterial rapid detection using optical scattering technology) that uses a red-diode laser, developed at the beginning of the 21<sup>st</sup> century at Purdue University, some 220 years after the Petri-plate discovery can identify and study bacteria directly on the plate as a diagnostic tool akin to Raman scattering and hyperspectral imaging systems for application in clinical and food microbiology laboratories.
Halometallate ionic liquids – revisited (2013)

Ionic liquids with chlorometallate anions may not have been the first ionic liquids, however, it was their development that lead to the recognition that ionic liquids are a distinct, and useful, class of (functional) materials. While much of the phenomenal interest and attention over the past two decades has focussed on 'air and water stable' ionic liquids, research and application of chlorometallate systems has continued unabated albeit largely out of the main spotlight. The defining characteristic of chlorometallates is the presence of complex anionic equilibria, which depend both on the type and on the concentration of metal present, and leads directly to their characteristic and individual properties. Here, we review the experimental techniques that can be applied to study and characterise the anion speciation in these ionic liquids and, using recent examples, illustrate how their applications base is evolving beyond traditional applications in Lewis acidic catalysis and electrochemistry through to uses as soft and component materials, in the ionothermal synthesis of semiconductors, gas storage systems and key components in the development of biomass processing.
Psychiatric manifestations of treatable hereditary metabolic disorders in adults (2014)

Detecting psychiatric disorders of secondary origin is a crucial concern for the psychiatrist. But how can this reliably be done among a large number of conditions, most of which have a very low prevalence? Metabolic screening undertaken in a population of subjects with psychosis demonstrated the presence of treatable metabolic disorders in a significant number of cases. The nature of the symptoms that should alert the clinician is also a fundamental issue and is not limited to psychosis. Hereditary metabolic disorders (HMD) are a rare but important cause of psychiatric disorders in adolescents and adults, the signs of which may remain isolated for years before other more specific organic signs appear. HMDs that present purely with psychiatric symptoms are very difficult to diagnose due to low awareness of these rare diseases among psychiatrists. However, it is important to identify HMDs in order to refer patients to specialist centres for appropriate management, disease-specific treatment and possible prevention of irreversible physical and neurological complications. Genetic counselling can also be provided. This review focuses on three HMD categories: acute, treatable HMDs (urea cycle abnormalities, remethylation disorders, acute intermittent porphyria); chronic, treatable HMDs (Wilson's disease, Niemann-Pick disease type C, homocystinuria due to cystathionine beta-synthase deficiency, cerebrotendinous xanthomatosis); and chronic HMDs that are difficult to treat (lysosomal storage diseases, X-linked adrenoleukodystrophy, creatine deficiency syndrome). We also propose an algorithm for the diagnosis of HMDs in patients with psychiatric symptoms.
Supplementary Figure 5 from A Diverse Array of Cancer-Associated <i>MTOR</i> Mutations Are Hyperactivating and Can Predict Rapamycin Sensitivity (2023)

&lt;p&gt;PDF file 73K, mTOR R1208C, V2006L, R2152C, and R2430M fail to confer increased S6K1 phosphorylation&lt;/p&gt;
On Aspects Of Nuclear-pumped Laser Power Beaming (2005)

Various energy sources, including both solar and nuclear systems, have been considered for laser power beaming. Nuclear systems (i.e. Nuclear Pumped Lasers) have unique advantages for space applications, since they can combine the power source and the laser in a single compact unit. Sale of electricity produced by combined plant offsets the high capital cost required for the laser system. For power beaming, a good beam quality is crucial. Here, the authors propose some novel improvements in the NPL beam quality. Desired characteristics for good beam quality are diffraction limited beams-minimum spot size, high extraction volume, and minimum gas lensing. A large extraction volume can be achieved by use of unstable resonators, while the spot size can be decreased by use of shorter wavelengths. Finally, gas lensing effects can be corrected by use of combined wall and volume pumping together with adaptive optics. The first step towards correcting for gas lensing is the study of dynamic conditions during reactor pumping. The theoretical modeling allows a time-dependent calculation of the density variations and the corresponding index-of-refraction variations. These results are then used to calculate, by means of ray tracing, the beam distortion due to gas lensing. Extension of the theoretical modelingmore » and the experiments from nuclear pumped cells to laser cavities (such as unstable resonators) is the second step in the study. Results from the work will be used to develop a combined pumping and adaptive optics method to improve beam quality.« less
Calculation of the effect of vibration on a region filled with a perfect viscous gas (2012)

The processes of heat and mass transfer in a region subjected to the vibration effect have been studied numerically. The effect of the vibration frequency on the behavior of the characteristics of gas located inside the region has been described. The one-dimensional problem has been solved.
Rapid Aqueous Spray Fabrication of Robust NiO—A Simple and Scalable Platform for Efficient Perovskite Solar Cells (2019)

We report on the development of an aqeuous spray coating process to deposit mechanically robust NiO for efficient perovskite solar cells.
Glucocorticoid stimulation of sodium absorption in colon epithelia is mediated by corticosteroid IB receptor. (1984)

Studies with RU26988, a synthetic glucocorticoid which does not bind to aldosterone receptors, suggest glucocorticoid-induced colonic cation transport is affected through glucocorticoid-specific receptors. RU26988 produced a 700% increase in sodium absorption and doubled transmural potential difference in proximal and distal colon of adrenalectomized rats. Scatchard analysis suggested a single class of receptors with a KD of approximately 10(-9) M. Competition of unlabeled steroids for [3H]triamcinolone acetonide-binding sites paralleled the steroids' biologic potency as glucocorticoids. Heat treatment (25 degrees C, 30 min) markedly enhanced binding of the glucocorticoid-receptor complexes to DNA-cellulose. The activated receptor from both proximal and distal colon was eluted in the prewash from DEAE-Sephadex A-50 anion exchange columns both in the presence and absence of protease inhibitors and has an estimated molecular weight (Stokes radius) of 33,000-37,000 (25-26 A). These results identify the colonic receptor as glucocorticoid binder IB, a receptor previously identified as the major binder only in kidney cortex. The finding of an apparently unique receptor in the two tissues where glucocorticoids stimulate cation transport suggests that the phenotypic response mediated by glucocorticoids in different tissues might be determined by the structure of the receptor and that glucocorticoid binder IB is the glucocorticoid cation transport receptor.
Table S1-S5 from Regulation of eIF4F Translation Initiation Complex by the Peptidyl Prolyl Isomerase FKBP7 in Taxane-resistant Prostate Cancer (2023)

&lt;p&gt;Table S1A: Signature of 998 differentially expressed genes between various resistant IGR-CaP1 cells and parental IGR-CaP1 Table S1B: Gene Ontology information on the 998 gene signature Table S2A: List of the 34 upregulated hits from the image-based high-content screen Table S2B: Gene Ontology information about the 34 hits issued from the image-based screen Table S3: Clinical data of patients recruited for tissue microarray (TMA) Table S4A: Specific partners of FKBP7 in RPE-1 cells Table S4B: Specific partners of FKBP7 in IGR-CaP1-Dtx-R cells Table S5A: SILAC on RPE-1 cells. Table S5B: SILAC on IGR-CaP1-Dtx-R cells.&lt;/p&gt;
Intraductal Administration of an NK1 Receptor Antagonist Attenuates the Inflammatory Response to Retrograde Infusion of Radiological Contrast in Rats: Implications for the Pathogenesis and Prevention of ERCP-Induced Pancreatitis (2003)

When an NK1 receptor antagonist is delivered along with the contrast media there is significant reduction in the pancreatic inflammation caused by intraductal contrast infusion. These results provide some insight into the pathogenesis of ERCP induced pancreatitis as well as present novel pharmacological targets for its prevention.
ACUTE POSTOPERATIVE INFECTIONS AFTER TOTAL KNEE ARTHROPLASTIES: ESR, CRP, AND ASPIRATION THRESHOLDS (2020)

Introduction Diagnosing acute postoperative periprosthetic joint infections (PJIs) after primary total knee arthroplasties (TKAs) remains difficult. Published diagnostic thresholds for ESR, CRP, an...
Packet recovery in high-speed networks using coding and buffer management (2002)

A technique for fiber-optic networks based on forward-error correction (FEC) that allows the destination to reconstruct missing data packets by using redundant parity packets that the source adds to each block of data packets is presented. Methods for generating several types of parity packets are described, along with decoding techniques and their implementations. Algorithms are presented for packet interleaving and selective rejection of packets from node buffers, both of which disperse missing packets among many blocks, thereby reducing the required coding complexity. Performance evaluation, by both analytic and simulation models, shows that this technique can result in a reduction of up to three orders of magnitude in the packet loss rate.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Predicting the Optical Performance of Eyes Implanted with IOLs to Correct Spherical Aberration (2006)

A "virtual surgery" approach was designed to predict the optical performance in pseudophakic eyes. In each subject, it was possible to obtain the eye's optical performance with a particular IOL and biometric data after surgery. Specifically, this modeling can be used to evaluate the tolerances to misalignments and depth of focus of IOLs correcting spherical aberration in actual eyes. This approach is quite powerful and is especially applicable to the study of current and future aberration-correction IOL designs.
Biocompatible metal–organic frameworks for the storage and therapeutic delivery of hydrogen sulfide (2021)

Hydrogen sulfide (H<sub>2</sub>S) is an endogenous gasotransmitter with potential therapeutic value for treating a range of disorders, such as ischemia-reperfusion injury resulting from a myocardial infarction or stroke. However, the medicinal delivery of H<sub>2</sub>S is hindered by its corrosive and toxic nature. In addition, small molecule H<sub>2</sub>S donors often generate other reactive and sulfur-containing species upon H<sub>2</sub>S release, leading to unwanted side effects. Here, we demonstrate that H<sub>2</sub>S release from biocompatible porous solids, namely metal-organic frameworks (MOFs), is a promising alternative strategy for H<sub>2</sub>S delivery under physiologically relevant conditions. In particular, through gas adsorption measurements and density functional theory calculations we establish that H<sub>2</sub>S binds strongly and reversibly within the tetrahedral pockets of the fumaric acid-derived framework MOF-801 and the mesaconic acid-derived framework Zr-mes, as well as the new itaconic acid-derived framework CORN-MOF-2. These features make all three frameworks among the best materials identified to date for the capture, storage, and delivery of H<sub>2</sub>S. In addition, these frameworks are non-toxic to HeLa cells and capable of releasing H<sub>2</sub>S under aqueous conditions, as confirmed by fluorescence assays. Last, a cellular ischemia-reperfusion injury model using H9c2 rat cardiomyoblast cells corroborates that H<sub>2</sub>S-loaded MOF-801 is capable of mitigating hypoxia-reoxygenation injury, likely due to the release of H<sub>2</sub>S. Overall, our findings suggest that H<sub>2</sub>S-loaded MOFs represent a new family of easily-handled solid sources of H<sub>2</sub>S that merit further investigation as therapeutic agents. In addition, our findings add Zr-mes and CORN-MOF-2 to the growing lexicon of biocompatible MOFs suitable for drug delivery.
ChemInform Abstract: A New Method for the Formation of Nitrogen‐Containing Ring Systems via the Intramolecular Photocycloaddition of Vinylogous Amides. A Synthesis of Mesembrine. (1988)

Abstract Irradiation of the vinylogous amide (I) in MeCN does not afford the expected cyclized product but the compound (II) which results from photoaddition and retro‐Mannich fragmentation.
Prof. Millie Dresselhaus (1930–2017), Carbon Nanomaterials Pioneer (2017)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTADDITION / CORRECTIONThis article has been corrected. View the notice.Prof. Millie Dresselhaus (1930–2017), Carbon Nanomaterials PioneerYan Li*, Jillian M. Buriak, Yury Gogotsi, Mark C. Hersam, Cherie R. Kagan, and Paul S. Weiss*Cite this: ACS Nano 2017, 11, 3, 2307–2308Publication Date (Web):March 17, 2017Publication History Published online17 March 2017Published inissue 28 March 2017https://pubs.acs.org/doi/10.1021/acsnano.7b01805https://doi.org/10.1021/acsnano.7b01805editorialACS PublicationsCopyright © 2017 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views4367Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (2 MB) Get e-Alertsclose Get e-Alerts
Biosynthetic studies of marine lipids. 39. 19-Norsterols: the course of C-19 methyl elimination (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBiosynthetic studies of marine lipids. 39. 19-Norsterols: the course of C-19 methyl eliminationMichael H. Rabinowitz and Carl DjerassiCite this: J. Am. Chem. Soc. 1992, 114, 1, 304–317Publication Date (Print):January 1, 1992Publication History Published online1 May 2002Published inissue 1 January 1992https://pubs.acs.org/doi/10.1021/ja00027a039https://doi.org/10.1021/ja00027a039research-articleACS PublicationsRequest reuse permissionsArticle Views831Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
LEF1 in Androgen-Independent Prostate Cancer: Regulation of Androgen Receptor Expression, Prostate Cancer Growth, and Invasion (2009)

A major obstacle in treating prostate cancer is the development of androgen-independent disease. In this study, we examined LEF1 expression in androgen-independent cancer as well as its regulation of androgen receptor (AR) expression, prostate cancer growth, and invasion in androgen-independent prostate cancer cells. Affymetrix microarray analysis of LNCaP and LNCaP-AI (androgen-independent variant LNCaP) cells revealed 100-fold increases in LEF1 expression in LNCaP-AI cells. We showed that LEF1 overexpression in LNCaP cells resulted in increased AR expression and consequently enhanced growth and invasion ability, whereas LEF1 knockdown in LNCaP-AI cells decreased AR expression and, subsequently, growth and invasion capacity. Chromatin immunoprecipitation, gel shift, and luciferase assays confirmed LEF1 occupancy and regulation of the AR promoter. Thus, we identified LEF1 as a potential marker for androgen-independent disease and as a key regulator of AR expression and prostate cancer growth and invasion. LEF1 is highly expressed in androgen-independent prostate cancer, potentially serving as a marker for androgen-independent disease.
Indoor Localiza tion (2015)

Wi-Fi-based indoor localization is a solved problem --- given a space with enough Wi-Fi access points (APs) and a set of radio frequency (RF) signal strength measurements that profile the environment, we can provide a service that can accurately locate uncalibrated devices in that space. No one would argue with this assertion, yet after more than 15 years of research, there are no pervasive products and the research community continues to work on this problem. Why?