gebhart/patrepeval huggingface dataset:
Proceedings of the NETL Workshop on Fuel Cell Modeling (2000)

This workshop was the first U.S. DOE sponsored meeting devoted to fuel cell modeling. The workshop was attended by over 45 people from industry, universities, and the government. The goals of the meeting were to assess the status of fuel cell modeling, and determine how new developments in fuel cell modeling can improve cell design, stack design, and power system design. The primary focus was on cell and stack modeling. Following a review of DOE/NETL fuel cell related programs and activities, Professor Robert Selman (Illinois Institute of Technology) kicked off the technical portion of the workshop by presenting an overview of fuel cell phenomena and the status of fuel cell modeling. This overview provided the necessary background for establishing a common framework for discussing fuel cell modeling. A distinction was made between micro modeling, electrode modeling, cell modeling, stack modeling, and system modeling. It was proposed that all modeling levels be supported for further development. In addition, due to significant advances being made outside the U.S., it was proposed that dialog/exchange with other international researchers be established. Following the Overview Session, eight leading researchers in modeling gave individual presentations. These presentations provided additional information on the status and present direction of model developments. All these presentations can be found in Attachment A. Before the workshop, a survey was sent out requesting comments from the attendees. Results from this survey can be found in Attachment B. This survey was then used as initial talking points at the individual breakout sessions on the afternoon of the workshop. Breakouts were organized by microfundamental modeling, cell modeling, stack modeling, and systems modeling.
Image retargeting for wearable devices (2016)

Small displays on wearable devices pose new challenges to presenting images. Image retargeting methods developed for mobile devices assume larger displays and are not adequate. This paper reports new approaches to image retargeting for wearable devices. Key to the proposed approach is identifying and presenting regions of interest that allows users to comprehend content and context. The system was implemented and evaluated on an Android watch. Subjective evaluation of the proposed approach shows that the proposed approach is effective and improves user experience.
Pterostilbene, a natural phenolic compound, synergizes the antineoplastic effects of megestrol acetate in endometrial cancer (2017)

Endometrial cancer is the most common gynecologic cancer in the United States and its incidence and mortality has been rising over the past decade. Few treatment options are available for patients with advanced and recurring endometrial cancers. Novel therapies, which are frequently toxic, are difficult to establish in this patient population which tends to be older and plagued by comorbidities such as diabetes mellitus and hypertension. Therefore, novel, non-toxic therapies are urgently needed. Megestrol acetate is a frequently used drug in endometrial cancer patients. However, its response rate is only 20-30%. To enhance the activity of megestrol acetate in endometrial cancer patients, we explored the potential of combining natural supplements with megestrol acetate and found that the addition of the natural phenolic compound, pterostilbene, to megestrol acetate resulted in a synergistic inhibition of cancer cell growth in vitro and an enhanced reduction of tumor growth in a xenograft mouse model. In addition, dual treatment led to attenuation of signaling pathways, as well as cell cycle and survival pathways. Our results demonstrated for the first time that the anti-tumor activity of megestrol acetate can be enhanced by combining with pterostilbene, providing an insight into the potential application of pterostilbene and megestrol acetate combination for the treatment of endometrial cancer.
Transcription Factors Sp1 and Sp3 Alter Vascular Endothelial Growth Factor Receptor Expression through a Novel Recognition Sequence (1998)

Kinase domain receptor (KDR) is a high affinity, endothelial cell-specific, autophosphorylating tyrosine kinase receptor for vascular endothelial growth factor. This transcriptionally regulated receptor is a critical mediator of endothelial cell (EC) growth and vascular development. In this study, we identify a DNA element modulating KDR promoter activity and evaluate the nuclear binding proteins accounting for a portion of the cell-type specificity of the region. KDR promoter luciferase activity was retained within -85/+296 and was 10-30-fold higher in EC than non-EC. Electrophoretic mobility shift assays demonstrated specific nuclear protein binding to -85/-64, and single point mutations suggested important binding nucleotides between -79/-68 with five critical bases between -74/-70 (5'-CTCCT-3'). DNA-protein complexes were displaced by Sp1 consensus sequence oligodeoxynucleotides and supershifted by Sp1- and Sp3-specific antibodies. Sp1 and Sp3 protein in EC nuclear extracts bound the -79/-68 region even when all surrounding classic Sp1 recognition sites were removed. Sp1 protein in nuclear extracts was 4-24-fold higher in EC than non-EC, whereas Sp3 was 3-7-fold higher. Sp1/Sp3 ratios in EC were 2-10-fold higher. Overexpression of Sp1 protein increased KDR promoter activity 3-fold in both EC and non-EC, whereas simultaneous co-expression of Sp3 attenuated this response. An Sp1 consensus sequence cis element "decoy" reduced EC KDR promoter activity and mRNA expression by 85 and 69%, respectively. An antisense phosphorothioate oligodeoxynucleotide to Sp1 inhibited Sp1 and KDR protein expression by 66 and 68%, respectively, without changing Sp3 protein expression. These data illustrate that Sp1 and Sp3 modulate KDR promoter activity through a novel recognition binding sequence. However, since Sp1-mediated promoter activation is attenuated by Sp3, endothelial selective KDR promoter activity may be partially regulated by variations in the Sp1/Sp3 ratio.
Two-dimensional Mo1.33C MXene with divacancy ordering prepared from parent 3D laminate with in-plane chemical ordering (2017)

The exploration of two-dimensional solids is an active area of materials discovery. Research in this area has given us structures spanning graphene to dichalcogenides, and more recently 2D transition metal carbides (MXenes). One of the challenges now is to master ordering within the atomic sheets. Herein, we present a top-down, high-yield, facile route for the controlled introduction of ordered divacancies in MXenes. By designing a parent 3D atomic laminate, (Mo<sub>2/3</sub>Sc<sub>1/3</sub>)<sub>2</sub>AlC, with in-plane chemical ordering, and by selectively etching the Al and Sc atoms, we show evidence for 2D Mo<sub>1.33</sub>C sheets with ordered metal divacancies and high electrical conductivities. At ∼1,100 F cm<sup>-3</sup>, this 2D material exhibits a 65% higher volumetric capacitance than its counterpart, Mo<sub>2</sub>C, with no vacancies, and one of the highest volumetric capacitance values ever reported, to the best of our knowledge. This structural design on the atomic scale may alter and expand the concept of property-tailoring of 2D materials.
Fusion Bonding Simulations of Semi-Crystalline Polymer Composites in the Extrusion Deposition Additive Manufacturing Process (2017)

Extrusion Deposition Additive Manufacturing (EDAM) is a technology where 3-D digital objects are manufactured extruding beads of molten material in a layer-by-layer basis. This technology offers the flexibility for processing pelletized material, and thus a semi-crystalline polymer highly-filled with carbon fiber has been used for printing. Significant technology improvements in the EDAM technology have been made recently, however, the design of the printing strategy is still mostly driven by empirical development. Hence, there is a need for simulation tools that capture the phenomena involved in the EDAM process to drive the development and optimization of this technology. Currently, one limitation of printed parts in terms of mechanical properties is the strength of the interface developed between printed layers. Therefore, the focus of this work is to couple the phenomena involved in the bonding process of adjacent layers to predict the degree of bonding, such as the temperature history, the melting and crystallization of the semi-crystalline polymer and the diffusion of polymer chains. The models utilized to describe these phenomena and their couplings were implemented in a UMATHT user subroutine in Abaqus to predict the evolution of the degree of bonding during the EDAM process. The effects of the couplings implemented in this approach are demonstrated by predicting the evolution of the degree of bonding throughout the simulation of the printing process of a geometry with sections that undergo different cooling and crystallization rates.
Rethinking Access Networks with High Performance Virtual Software BRASes (2013)

Broadband Remote Access Servers (BRASes) play a crucial role in today's networks, handling all traffic coming from access networks (e.g., DSL traffic), applying operator policies and providing the first IP point in the network. It is perhaps unsurprising then, that these are expensive, proprietary, difficult-to-upgrade boxes. They also represent a large, single point of failure, making operators even more reticent to deploy new functionality for fear it might seriously disrupt day-to-day operations. In order to remove some of these barriers to innovation, we advocate for turning BRASes from the monolithic hardware boxes they are today into flexible, virtualized, software-based devices running on inexpensive commodity hardware. As a proofof-concept, we present the implementation and performance of a software BRAS based on ClickOS, a tiny Xen virtual machine designed specifically for network processing. Our software BRAS prototype can establish subscriber sessions at rates above 1, 000 per second, requires only 1MB of memory per 1, 000 established sessions, can boot in milliseconds, and can handle traffic at 10Gb/s for almost all packet sizes.
A Convenient Synthesis of 1,7-Dibromo- and 1,7-Dichloropentacvclo[5.4.0.02,6.03,10.05,9]Undecane-8,11-diones (1989)

Abstract endo-Tricyclo[6.2.1.02,7]undeca-4,9-diene-3,6-dione reacts with X2-Sme2 (X [dbnd] Br, Cl) to afford the corresponding bis(α-haloenones) which then can be photocyclized to afford the title compounds in 62% and 30% overall yield, respectively.
DEVELOPMENT OF A TRAILER ATTENUATING CUSHION FOR VARIABLE MESSAGE SIGNS AND ARROW BOARDS (2003)

In 1993 the Federal Highway Administration (FHWA) adopted a policy that requires all roadside features placed within the clear zone to be evaluated according to the guidelines contained in NCHRP Report 350. Variable message sign trailers and arrow board trailers have never been tested under these safety evaluation guidelines. A full scale crash test and a review of work zone accident studies clearly indicates that these trailers are a serious roadside hazard and they are struck in approximately 15 percent of all work zone intrusion accidents. An attenuating cushion was developed that safely treats the full range of these trailers. Two full scale crash tests of the Trailer Attenuating Cushion were conducted to verify that the new designs meet NCHRP Report 350 guidelines. The new safety treatments are believed to be relatively inexpensive to build and easy to deploy. The new systems should reduce the severity of many ran-off-road crashes without a major increase in the cost of using variable message signs and arrow boards
Research of critical success factors of ERP implementation of WX company (2014)

Under the background of the transformation and upgrading of Chinese enterprises, transformation by informatization through the implementation of ERP is undoubtedly an effective means. And how to effectively increase the success rate of ERP implementation is an issue of common concern. By using method of case analysis and combining the ERP project of WX Company, this article analyses the critical success factors for ERP implementation and provides ERP implementation reference for labour-intensive manufacturing companies which are represented by WX Company.
Optical Thin Films with Extremely Low Refractive Index (2006)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text J. -. Xi, J. K. Kim, D. Ye, J. S. Juneja, T. -. Lu, S. Lin, and E. F. Schubert, "Optical Thin Films with Extremely Low Refractive Index," in Frontiers in Optics, OSA Technical Digest (CD) (Optica Publishing Group, 2006), paper JWD17. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
The GS-nitroxide JP4-039 improves intestinal barrier and stem cell recovery in irradiated mice (2018)

Total body irradiation (TBI) leads to dose- and tissue-specific lethality. In the current study, we demonstrate that a mitochondrion-targeted nitroxide JP4-039 given once 24 hours after 9-10 Gy TBI significantly improves mouse survival, and the recovery of intestinal barrier, differentiation and stem cell functions. The GI-protective effects are associated with rapid and selective induction of tight junction proteins and cytokines including TGF-β, IL-10, IL-17a, IL-22 and Notch signaling long before bone marrow depletion. However, no change was observed in crypt death or the expression of prototypic pro-inflammatory cytokines such as TNF-α, IL-6 or IL-1β. Surprisingly, bone marrow transplantation (BMT) performed 24 hours after TBI improves intestinal barrier and stem cell recovery with induction of IL-10, IL-17a, IL-22, and Notch signaling. Further, BMT-rescued TBI survivors display increased intestinal permeability, impaired ISC function and proliferation, but not obvious intestinal inflammation or increased epithelial death. These findings identify intestinal epithelium as a novel target of radiation mitigation, and potential strategies to enhance ISC recovery and regeneration after accidental or medical exposures.
Axial InAs(Sb) inserts in selective-area InAsP nanowires on InP for optoelectronics beyond 25 µm (2018)

e d fo r p u blic a tio n.Cit a tio n fo r fin al p u blis h e d ve r sio n: R e n, Di n g k u n, F a r r ell, Ala n C. a n d H uff a k er, Di a n a L. 2 0 1 8. Axial
Cross-dialectal acoustic data sharing for Arabic speech recognition (2004)

The automatic recognition of Arabic dialectal speech is a challenging task since Arabic dialects are essentially spoken varieties, for which only sparse resources (transcriptions and standardized acoustic data) are available to date. In this paper we describe the use of acoustic data from modern standard Arabic (MSA) to improve the recognition of Egyptian conversational Arabic (ECA). The cross-dialectal use of data is complicated by the fact that MSA is written without short vowels and other diacritics and thus has incomplete phonetic information. This problem is addressed by automatically vowelizing MSA data before combining it with ECA data. We described the vowelization procedure as well as speech recognition experiments and show that our technique yields improvements over our baseline system.
Successful lung transplant in a child with cystic fibrosis and persistent Blastobotrys rhaffinosifermentans infection (2014)

Fungal respiratory infections in patients with CF are a significant concern both pre- and post-lung transplantation (LTx). Fungal infection is associated with increased mortality post-LTx, and in the past decade, the prevalence of fungal colonization in Canadian pediatric patients with CF has increased. The emergence of novel fungal pathogens is particularly challenging to the transplant community, as little is known regarding their virulence and optimal management. We present a case of a successful double-lung transplant in a pediatric patient with CF who was infected pretransplantation with a novel yeast, Blastobotrys rhaffinosifermentans. This patient was treated successfully with aggressive antifungal therapy post-transplantation, followed by extended fungal prophylaxis. The significance of fungal colonization and infection in children with CF pre- and post-LTx is reviewed.
Optical and magneto-optical properties of MnPt3 films (abstract) (1997)

Optically thick films of MnPt3 were prepared by magnetron sputtering onto quartz substrates. Postdeposition annealing at 850 °C resulted in highly textured (111) films with the L12 (Cu3Au) structure. MnPt3 films are ferromagnetic with a Curie temperature of 380 °C, and they show large magneto-optical effects in the visible.12 These films also show a high degree of long-range order. The diagonal components of the dielectric tensor were determined using variable angle spectroscopic ellipsometry measurements over the spectral range 1.2–2.4 eV. Magneto-optic Kerr rotation and ellipticity measurements were made at near normal incidence over the spectral range 1.4–3.6 eV to determine the off-diagonal components of the MnPt3 dielectric tensor. First-principles electronic structure calculations were carried out for the ordered MnPt3 structure, and from these the components of the dielectric tensor were calculated. We find excellent agreement between the measured and calculated diagonal components, but only fair agreement for the off-diagonal components.
Analysis of vertical and horizontal circular C-arm trajectories (2011)

C-arm angiography systems offer great flexibility in the acquisition of trajectories for computed tomography. Theoretically, these systems are able to scan patients while standing in an upright position. This would allow novel insights into structural changes of the human anatomy while weight bearing. However, this would require a scan on a horizontal trajectory parallel to the ground floor which is currently not supported by standard C-arm CT acquisition protocols. In this paper, we compared the standard vertical and the new horizontal scanning trajectories by analysis of the source positions and source to detector distances during the scan. We employed a C-arm calibration phantom to compute the exact scan geometry. Based on the analysis of the projection matrices, we computed the source position in 3D and the source to detector distance for each projection. We then used the calibrated scan geometries to reconstruct the calibration phantom. Based on this reconstruction in comparison to the ideal phantom geometry we also evaluated the geometric reconstruction error. As expected, both the vertical and the horizontal scan trajectories exhibit a significant C-arm "wobble". But in both kinds of trajectories, the reproducibility over several scans was comparable. We were able to reconstruct the calibration phantom with satisfactory geometric reconstruction accuracy. With a reconstruction error of 0.2 mm, we conclude that horizontal C-arm scans are possible and show properties similar to those of vertical C-arm scans. The remaining challenge is compensation for the involuntary movement of the standing subject during a weight-bearing acquisition. We investigated this using an optical tracking system and found that the average movement at the knee while standing upright for 5 seconds is between 0.42 mm and 0.54 mm, and goes up to as much as 12 mm when the subject is holding a 60&deg; squat. This involuntary motion is much larger than the reconstruction accuracy. Hence, we expect artifacts in reconstructions to be significant for upright positions, and overwhelming in squat positions if no motion correction is applied.
P-GLYCOPROTEIN FUNCTION IN HUMAN ALLOIMMUNE INTERACTIONS. (2000)

1Laboratory of Immunogenetics and Transplantation, Brigham and Women's Hospital, Boston, MA;2Division of Nephrology, Children's Hospital, Boston, MA.
Analysis and compact modeling of a vertical grounded-base n-p-n bipolar transistor used as ESD protection in a smart power technology (2001)

A thorough analysis of the physical mechanisms involved in a vertical grounded-base n-p-n bipolar transistor (VGBNPN) under electrostatic discharge (ESD) stress is first carried out by using two-dimensional (2-D) device simulation, transmission line pulse measurement (TLP) and photoemission experiments. This analysis is used to account for the unexpected low value of the VGBNPN snapback holding voltage under TLP stress. A compact model based on a new avalanche formulation resulting from the exact resolution of the ionization integral is therefore proposed.
Quasi-zero-dimensional cobalt-doped CeO2 dots on Pd catalysts for alcohol electro-oxidation with enhanced poisoning-tolerance (2017)

Deactivation of an anode catalyst resulting from the poisoning of CO<sub>ad</sub>-like intermediates is one of the major problems for methanol and ethanol electro-oxidation reactions (MOR & EOR), and remains a grand challenge towards achieving high performance for direct alcohol fuel cells (DAFCs). Herein, we report a new approach for the preparation of ultrafine cobalt-doped CeO<sub>2</sub> dots (Co-CeO<sub>2</sub>, d = 3.6 nm), which can be an effective anti-poisoning promoter for Pd catalysts towards MOR and EOR in alkaline media. Compared to Pd/CeO<sub>2</sub> and pure Pd, the hybrid Pd/Co-CeO<sub>2</sub> nanocomposite catalyst exhibited a much enhanced activity and remarkable anti-poisoning ability for both MOR and EOR. The nanocomposite catalyst showed much higher mass activity (4×) than a state-of-the-art PtRu catalyst. The promotional mechanism was elucidated using extensive characterization and density-functional theory (DFT). A bifunctional effect of the Co-CeO<sub>2</sub> dots was discovered to be due to (i) an enhanced electronic interaction between Co-CeO<sub>2</sub> and Pd dots and (ii) the increased oxygen storage capacity of Co-CeO<sub>2</sub> dots to facilitate the oxidation of CO<sub>ad</sub>. Therefore, the Pd/Co-CeO<sub>2</sub> nanocomposite appears to be a promising catalyst for advanced DAFCs with low cost and high performance.
A Method to Form Bonded Micromagnets Embedded in Silicon (2007)

In this work, samarium cobalt (SmCo) powder is utilized for the fabrication of micromagnetic structures embedded in silicon wafers. The fabrication process involves the dry packing of raw, magnetic powder (mean particle diameter of 5-10 μm) into etched cavities within the wafer. After the wafer is loaded with the powder, a 6 μm layer of polyimide is spun over the wafer's surface to seal the magnetic powder in place and permit the development of additional structures around the embedded magnets. The feature sizes achieved during the investigation range in thickness from 15 μm to the entire depth of the wafer (~500 μm), and in lateral dimensions from 150 μm to 600 μm. One set of processed micromagnets demonstrated a coercivity, H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</sub> = 141 kA/m (1.8 kOe), remanence, B <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r</sub> = 0.52 T (5.2 kG), and maximum energy product, (BH) <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">max</sub> = 23 kJ/m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> (2.9 MGOe).