gebhart/patrepeval huggingface dataset:
Clinical Studies with LSD-25 and Two Substances Related to Serotonin (1960)

In 1953, Twarog and Page (1) demonstrated that 5-hydroxytryptamine (serotonin) is present in relatively high concentrations in the brain. At about the same time Gaddum (2) and Woolley and Shaw (3) observed that LSD is a highly potent serotonin antagonist in such tissues as rat uterus and hypothesized that the hallucinogenic effect of LSD might be due to interference in the action of serotonin.
Highly-doped p-ZnSe formation by Li/sub 3/N diffusion (2002)

We found that Li/sub 3/N diffusion makes a good ohmic contact to MOCVD-grown ZnSe layers. Hall measurement at 300 K showed that the hole concentration and resistivity is 8.6x10/sup 17/ cm/sup -3/ and 0.4 /spl Omega/cm for the diffused layers at 470/spl deg/C. This result is comparable to that reported for highly N-doped ZnSe layers by MBE. It indicates that L/sub 3/N diffusion is effective for solving the ohmic contact problem of MOVPE-grown p-ZnSe without adding any complicated structures.
How Verified is My Code? Falsification-Driven Verification (T) (2015)

Formal verification has advanced to the point that developers can verify the correctness of small, critical modules. Unfortunately, despite considerable efforts, determining if a "verification" verifies what the author intends is still difficult. Previous approaches are difficult to understand and often limited in applicability. Developers need verification coverage in terms of the software they are verifying, not model checking diagnostics. We propose a methodology to allow developers to determine (and correct) what it is that they have verified, and tools to support that methodology. Our basic approach is based on a novel variation of mutation analysis and the idea of verification driven by falsification. We use the CBMC model checker to show that this approach is applicable not only to simple data structures and sorting routines, and verification of a routine in Mozilla's JavaScript engine, but to understanding an ongoing effort to verify the Linux kernel Read-Copy-Update (RCU) mechanism.
Monosubstituted Tetramethoxynaphthalenes (1989)

Abstract As new intermediates for the syntheses of monosubstituted naphthazarins and anthracyclines, several tetramethoxynaphthalenes having a substituent such as CH3, COOH, CN, Br, OAc, OH, and OMe groups were prepared from 1,4,5,8-tetramethoxynaphthalene and 2-formyl-1,4,5,8-tetramethoxynaphthalene.
Session details: Session 3B: Processing In/Near Memory (2021)

No abstract available.
Generalized Powering Functions and Their Application to Digital Signatures (2006)

This paper investigates some modular powering functions suitable for cryptography. It is well known that the Rabin encryption function is a 4-to-1 mapping and breaking its one-wayness is secure under the factoring assumption. The previously reported encryption schemes using a powering function are variants of either the 4-to-1 mapping or higher n-to-1 mapping, where n > 4. In this paper, we propose an optimized powering function that is a 3-to-1 mapping using a p 2 q-type modulus. The one-wayness of the proposed powering function is as hard as the infeasibility of the factoring problem. We present an efficient algorithm for computing the decryption for a p 2 q-type modulus, which requires neither modular inversion nor division. Moreover, we construct new provably secure digital signatures as an application of the optimized functions. In order to achieve provable security in the random oracle model, we usually randomize a message using random hashing or padding. However, we have to compute the randomization again if the randomized message is a non-cubic residue element -it is inefficient for long messages. We propose an algorithm that can deterministically find the unique cubic residue element for a randomly chosen element.
Synthesis and Characterization of High-Performance, Bio-Based Epoxy–Amine Networks Derived from Resveratrol (2020)

Resveratrol is a sustainable and versatile bio-derived phenolic compound that has shown promise as a high glass-transition temperature (Tg), flame-resistant building block for thermoset networks. In this study, three components of epoxy thermoset resins were synthesized from resveratrol: trans-resveratrol trisepoxy (1), dihydroresveratrol trisepoxy (2), and a trifunctional amine, 4,4′-((5-(4-(4-aminophenoxy)phenethyl)-1,3-phenylene)bis(oxy))dianiline (4). The epoxy monomers were low melting solids (mp < 80 °C) or thick oils consisting of primarily monomeric trisepoxides. Toxicity testing of 4 revealed that it was not mutagenic and had a low LD50 of 560 mg/kg, an aquatic toxicity of >2000 mg/L, and no cytotoxicity up to its solubility limit. The epoxy monomers were cured with 4,4′-methylenedianiline (3) and 4 to produce four epoxy–amine networks (A–D). Networks C and D, prepared with the resveratrol-derived aniline, contained up to 52.6% bio-based material. The moisture uptake, thermal stability, and dry/wet thermomechanical properties of the networks were measured. The networks had Tg’s as high as 285 °C, approximately 110 °C higher than networks based on petroleum-derived bisphenol A (BPA). In addition, the resveratrol networks had char yields as high as 51 and 46% in nitrogen and air, respectively, compared to ca. 15 and 5%, respectively, for BPA-based networks. Overall, this study shows the advantages of resveratrol-based epoxy and amine monomers as components of sustainable, low-toxicity, high-temperature resin systems.
Functional Cell-Based Assays in Microliter Volumes for Ultra-High Throughput Screening (2008)

Functional cell-based assays have gained increasing importance for microplate-based high throughput screening (HTS). The use of high-density microplates, most prominently 1536-well plates, and miniaturized assay formats allow screening of comprehensive compound collections with more than 1 million compounds at ultra-high throughput, i.e. in excess of 100,000 samples per day. uHTS operations with numerous campaigns per year should generally support this throughput at all different steps of the process, including the underlying compound logistics, the (automated) testing of the corporate compound collection in the bioassay, and the subsequent follow-up studies for hit confirmation and characterization. A growing number of reports document the general feasibility of cell-based uHTS in microliter volumes. In addition, full automation with integrated robotic systems allows the realization of also complex assay protocols with multiple liquid handling and signal detection steps. For this review, cell-based assays are categorized based on the kinetics of the cellular response to be quantified in the test and the readout method employed. Thus, assays measuring fast cellular responses with high temporal resolution, e.g., receptor mediated calcium signals or changes in membrane potential, are at one end of this spectrum, while tests quantifying cellular transcriptional responses mark the opposite end. Trends for cell-based uHTS assays developed at Bayer-Schering Pharma are, first, to incorporate assay integral reference signals allowing the experimental differentiation of target hits from non-specifically acting compounds, and second, to make use of kinetic, real-time readouts providing additional information on the mode-of-action of test compounds.
Preface (2014)

Digital signal processing (DSP) is one of the most prominent areas in engineering, including subfields such as speech and image processing, statistical data processing, spectral estimation, biomedical applications, and many others. As the name suggests, the goal is to perform various signal processing tasks (e.g., filtering, amplification, and more) in the digital domain where design, verification, and implementation are considerably simplified compared with analog signal processing. DSP is the basis of many areas of technology, and is one of the most powerful technologies that have shaped science and engineering in the past century.
Angular distribution measurement of high-energy argon neutral and ion in a 13.56 MHz capacitively-coupled plasma (2021)

Angular distributions of high energy neutrals and ions, impinging on an RF-biased electrode in a 13.56 MHz capacitively-coupled argon plasma were investigated. Ions and neutrals were introduced into a drift chamber that was directly connected to the RF electrode. A two-dimensional beam image was measured by a micro-channel plate. Neutral and ion beams were separated by an electrostatic deflector in the drift chamber. Angular distribution widths for ion and neutral were less than 1° at self-bias voltages above 300 V and monotonically decreased with increasing the self-bias voltage. Neutral angular distribution width was larger than that of ion, irrespective of self-bias voltage.
Supplementary Table 1, 2 and 4 from RAS–MAPK Reactivation Facilitates Acquired Resistance in <i>FGFR1</i>-Amplified Lung Cancer and Underlies a Rationale for Upfront FGFR–MEK Blockade (2023)

&lt;p&gt;Supplementary Table 1 and 2 describe pharmacologic properties of BGJ398 and FIIN-3 and Supplementary Table 4 describes the characteristics of cellular models employed in the colony formation assays.&lt;/p&gt;
Robust beamforming with decentralized interference coordination in cognitive radio networks (2014)

This paper considers an underlay cognitive radio network where primary and secondary networks coexist. The optimization target is to minimize the sum power of secondary transmitters while satisfying the worst case minimum SINR constraint for each secondary user (SU) and maximum aggregate interference constraint for each primary user (PU). Imperfect channel state information (CSI) is assumed, and the corresponding CSI errors are bounded by ellipsoids. We propose an alternating direction method of multipliers-based decentralized beamforming algorithm which relies only on local imperfect CSI and limited backhaul signaling. The convergence behavior of the proposed algorithm is studied via numerical examples.
Hydrogen storage material and process using graphite additive with metal-doped complex hydrides (2023)

A hydrogen storage material having improved hydrogen absorbtion and desorption kinetics is provided by adding graphite to a complex hydride such as a metal-doped alanate, i.e., NaAlH.sub.4. The incorporation of graphite into the complex hydride significantly enhances the rate of hydrogen absorbtion and desorption and lowers the desorption temperature needed to release stored hydrogen.
Fully plated metal electrodes for plasma‐display panels (2004)

Abstract— We investigated the feasibility of employing a full‐plating processes for the metal electrodes in PDPs. Using deposition with a full‐plating process, we succeeded in fabricating copper electrodes with a thicknesses of over 10 μm. Moreover, we fabricated and operated panels with fully plated bus electrodes. These plating processes seem to hold promise in the simultaneous pursuit of metal electrodes with the highest conductance and lower costs.
ChemInform Abstract: Supported Gold(III) Catalysts for Highly Efficient Three‐Component Coupling Reactions. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Optimization and precise exceptions in dynamic compilation (2001)

Maintaining precise exceptions is an important aspect of achieving full compatibility with a legacy architecture. While asynchronous exceptions can be deferred to an appropriate boundary in the code, synchronous exceptions must be taken when they occur. This introduces uncertainty into liveness analysis since processor state that is otherwise dead may be exposed when an exception handler is invoked. Previous systems either had to sacrifice full compatibility to achieve more freedom to perform optimization, use less aggressive optimization or rely on hardware support.In this work, we demonstrate how aggressive optimization can be used in conjunction with dynamic compilation without the need for specialized hardware. The approach is based on maintaining enough state to recompute the processor state when an unpredicted event such as a synchronous exception may make otherwise dead processor state visible. The transformations necessary to preserve precise exception capability can be performed in linear time.
Gas phase methanol synthesis with Raman spectroscopy for gas composition monitoring (2020)

Applicability of Raman spectroscopy for time-resolved gas composition monitoring during direct methanol synthesis <i>via</i> carbon dioxide hydrogenation was investigated. A series of methanol synthesis experiments with varied reactor conditions was conducted and the reactor outlet stream was analyzed with in-line gas Raman spectroscopy. Concentrations of H<sub>2</sub>, CO<sub>2</sub> and CO were determined directly from the acquired spectral data. For evaluation of methanol and water content a data reconciliation algorithm was developed. The algorithm involves estimation of the occurring chemical reactions' extents by iterative minimization of the difference between concentration values acquired from the experimental data and concentration values computed based on the mass conservation principle. The obtained experimental concentrations were compared and validated against the results of the reactor mathematical modeling, which is based upon a well-established kinetic interpretation of the process. The findings indicate good repeatability and accuracy of the developed gas analysis system, which together with the advantageous temporal resolution of the method, make Raman spectroscopy a promising technique for fast response monitoring of the process.
Decoding the Viewpoint and Identity of Faces and Bodies (2019)

Our visual system allows us to recognize familiar individuals across different viewpoints, despite large differences in low-level visual information. Previous neuroimaging research has shown that there is a hierarchical organisation across face-responsive brain regions, with lower-level regions representing head viewpoint and higher-level regions representing face identity. In this study, we investigated whether a similar hierarchy is present in body-responsive brain regions, as we also see bodies from many different viewpoints and psychological research has shown we also use information from the body for identification. Furthermore, we investigated whether representations of viewpoint and identity are face and body specific, or generalise to a common representation. We trained participants to recognize three individuals from images of their face and body. We then recorded their brain activity using fMRI while they viewed images of the face and body (shown separately) of the individuals from different viewpoints. Participants responded to the identity or viewpoint, revealing differences in neural representation depending on which feature participants attended to. We found that the occipital face area and extrastriate body area contain representations of face and body viewpoint, and that these viewpoint representations generalize across the face and body (e.g. a classifier trained to distinguish viewpoint of faces could decode viewpoint of bodies). Furthermore, we found that the fusiform body area (FBA) represents body identity in a viewpoint-invariant manner. We decoded face identity in the FBA, and also found a trend in the anterior temporal face area, that has previously been shown to represent face identity. In total, our results show that lower-level face- and body-responsive regions represent viewpoint, and these representations are not driven by low-level visual similarity. We show that the FBA represents body identity, indicating that a similar hierarchy is present for body identity representations in occipi-totemporal cortex as has been previously identified for faces.
Macroscale angled ultrasonic standing waves: A novel approach for particle manipulation (2017)

Macro scale acoustophoretic devices use radiation forces to trap particles inside a standing wave to separate them from a mixture in a continuous fashion. However, these devices are limited by factors such as flow rates, residence times, and temperature rise which could be detrimental for certain applications. A novel method of separating, sorting and differentiating various particles using bulk angled ultrasonic standing waves is presented. This technique offers very sensitive separation capability with respect to size and acoustic contrast of particles. Universal curves are developed for particle deflection from the bulk flow direction at all wave angles as a function of a non-dimensional parameter defined by the ratio of acoustic radiation force to viscous drag force. Both CFD (Computational Fluid Dynamics) and model test data verify the analytical predictions. New macro-scale, ultrasonic separator concepts are presented that use the angle wave technology to effectively deflect and/or separate microcarrier beads from a flowing mixture at high speeds when compared to conventional ultrasonic separators. Model test data verify the ability to move, differentiate, separate, or fractionate particles in suspension by size and acoustic contrast.
Burstiness and scaling in the structure of low-power wireless links (2009)

We observe that low-power wireless links have non-trivial time-scaling characteristics at both the physical- and link-layers. Packet reception rate (PRR) analysis shows that links are bursty rather than constant, i.e., their reception quality varies greatly from the overall packet reception rate at different times. Furthermore, this variation is seen at many timescales. We provide a possible explanation for burstiness using wavelet analysis of RSSI traces from a variety of wireless links. We show that these traces can be considered as consistent with statistical self-similarity but not with long range dependence. Using the variance in RSSI, we suggest a way to easily characterize when scaling occurs. Finally, while current simulators do not capture scaling, we propose and validate a possible modeling technique for network links that conforms to scaling phenomena.
The Human Monocytic Leukemia Zinc Finger Histone Acetyltransferase Domain Contains DNA-binding Activity Implicated in Chromatin Targeting (2007)

The human monocytic leukemia zinc finger (MOZ) protein is an essential transcriptional coactivator and histone acetyltransferase (HAT) that plays a primary role in the differentiation of erythroid and myeloid cells and is required to maintain hematopoietic stem cells. Chromosomal translocations involving the HAT-encoded region are also associated with acute myeloid leukemia. Here we present the x-ray crystal structure of the MOZ HAT domain and related biochemical studies. We find that the HAT domain contains a central region that is structurally and functionally conserved with the yeast MYST HAT protein Esa1, but contains more divergent N- and C-terminal regions harboring a TFIIIA-type zinc finger and helix-turn-helix DNA-binding motifs. Solution DNA-binding and acetyltransferase activity assays, in concert with mutagenesis, confirm that the MOZ HAT domain binds strongly to DNA through the zinc finger and helix-turn-helix motifs and that DNA binding and catalysis are not mutually exclusive. Consistent with the DNA-binding properties of MOZ, we also show that MOZ is able to acetylate nucleosomes and free histones equally well, whereas other HATs prefer free histones. Our results reveal, for the first time, that enzymatic and DNA-targeting activities can be contained within the same chromatin regulatory domain.
Supplemental Video M5 from A Systematic Comparison of <sup>18</sup>F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment (2023)

&lt;p&gt;Supplemental Video M5. 18FC-SNAT uptake in naive tumors&lt;/p&gt;
Heterogeneous Integration of Microscale Gallium Nitride Transistors by Micro-Transfer-Printing (2016)

Discrete gallium nitride high electron mobility transistors (HEMTs) are fabricated on oriented silicon, then undercut and assembled onto non-native silicon CMOS wafers by elastomer stamp micro-transfer-printing. The thin, less than 5 µm thick, gallium nitride transistors were then electrically interconnected using conventional thin-film metallization processes. Electrical measurements reveal that the heterogeneous integration process is benign to the underlying silicon transistors, and that the heterogeneous wide bandgap GaN transistors maintain their characteristic high voltage performance after being undercut and transferred to the non-native CMOS wafer.
Isomeric monoacetylmono(1-hydroxyethyl)deuteroporphyrins: synthesis, characterization, and use for the synthesis of regioselectively methyl- and vinyl-deuterated hemins (1990)

Treatment of hematoporphyrin IX dimethyl ester (7) with tetrapropylammonium perruthenate (Prn4N)(Ru04) and N-methylmorpholine N-oxide affords a high yield of the separable monoacetylmono(1-hydroxyethyl)-deuteroporphyrin isomers 5 and 6. Proton NMR NOE experiments and chemical transformations involving specific individual deuteration at the 1- and 3-methyls and 2- and 4-vinyls are used to characterize the isomers. © 1990, American Chemical Society. All rights reserved.
Compact planar inverted-F antenna system for MIMO USB dongle operating in 2.5—2.7 GHz band (2012)

This paper presents a design of a compact planar MIMO antenna system for an LTE/WiMAX USB dongle operating in the 2.5-2.7 GHz frequency band. The proposed MIMO antenna system consists of two planar inverted-F antenna elements with high isolation between them. The high isolation is achieved by mirror symmetrical orientation of the developed printed inverted-F antenna elements relative to each other. This provides pattern diversity between the two different antenna elements. The antenna system is realized using the standard FR4 PCB substrate that leads to a low production cost. The occupied antenna area has the dimensions of 21.5 mm × 20 mm that is only a fraction of the operating wavelength (115 mm at 2.6 GHz). The designed MIMO antenna system has the bandwidth of more than 200 MHz at the reflection coefficient level below -8 dB. The isolation between the antenna elements across the radiation bandwidth exceeds 8.5 dB and the envelope correlation coefficient is lower than 0.1. Experimental measurements of the fabricated antenna system confirm the results of electromagnetic simulation.