gebhart/patrepeval huggingface dataset:
Laser beam-ion beam photodissociation studies of C6H6+ radical cations: the 2,4-hexadiyne system (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLaser beam-ion beam photodissociation studies of C6H6+ radical cations: the 2,4-hexadiyne systemR. E. Krailler, D. H. Russell, M. F. Jarrold, and M. T. BowersCite this: J. Am. Chem. Soc. 1985, 107, 8, 2346–2354Publication Date (Print):April 1, 1985Publication History Published online1 May 2002Published inissue 1 April 1985https://pubs.acs.org/doi/10.1021/ja00294a026https://doi.org/10.1021/ja00294a026research-articleACS PublicationsRequest reuse permissionsArticle Views71Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Transport Layer Security (TLS) Transport Mapping for Syslog (2009)

This document specifies an Internet standards track protocol for the Internet community, and requests discussion and suggestions for improvements. Please refer to the current edition of the &amp;quot;Internet Official Protocol Standards &amp;quot; (STD 1) for the standardization state and status of this protocol. Distribution of this memo is unlimited. Copyright Notice Copyright (c) 2009 IETF Trust and the persons identified as the document authors. All rights reserved. This document is subject to BCP 78 and the IETF Trust’s Legal Provisions Relating to IETF Documents in effect on the date of publication of this document
Decoupling of deformation in the Upper Rhine Graben sediments. Seismic reflection and diffraction on 3-component Vertical Seismic Profiling (Soultz-sous-Forêts area) (2009)

The authors have decided to withdraw this article from publication in the C. R. Geoscience. A revised version will be published later. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.
Absorption of myo-inositol hexakisphosphate (InsP6) through the skin: study of the matrix effects. mechanism of phytate topical absorption (2005)

Myo-inositol hexakisphosphate (InsP6, phytate) is a molecule to which diverse beneficial properties have been attributed. Some of these properties are related to its dermatological use as discolouring agent, on preventing calcinosis cutis or due to its important role on premature aging. Other studies also seem to demonstrate a capacity of InsP6 to inhibit skin cancer. In this paper, the effect of the vehicle of topical administration of phytate is studied, using four groups of male Wistar rats (n = 6) fed with an InsP6 defficient diet and treated with a hydrophyl gel or an O/W moisturizing cream with two different concentrations of InsP6. Due to the correlation between InsP6 absorption and its urinary excretion, these last values were used to evaluate this process. It was found that phytate was absorbed through the skin using both a gel or a cream, demonstrating that its absorption is independent on the matrix used for topical treatment. However, urinary InsP6 values were slightly higher when using the gel, but in all cases values were much higher than those found with oral InsP6 treatment, due to the formation of insoluble species in the gastrointestinal tract when InsP6 is administered orally.
Model based pose estimation for autonomous operations in space (2003)

Presents a method for determining the 3D pose of a known object with the intent of autonomously controlling space hardware systems. Operations of interest include satellite on-orbit servicing and orbit transfer. Using a specially designed, adaptable vision server, stereo images are acquired and edge data is extracted. Corresponding points are found in the left and right edge data and 3D information is computed. This 3D data is then registered to a model of the object in such a way as to minimize the distance between the two data sets. Once the model is aligned with the data, the full 3D pose of the object is known; this information can then be used by a robot controller to compute a path to the object. The process runs continuously, giving the controller up-to-date information. Experimental results presented in this paper show the capabilities and robustness of the system.
New Strategies on the Development of Nanoparticle Technology (2011)

Processing of nanoparticles and nanocomposites has great potential for use in the application of various industrial fields including environmental remediation and renewable energy conversion. It is very important to develop their synthesis methods in which nanoparticles having controlled characteristics including size distribution, morphology, and composition can be produced. To be industrially relevant, the process needs to be simple, low in cost, and have both continuous operation and high production rate. In this lecture, after briefly introducing of the gas‐phase and liquid‐phase synthesis methods for nanoparticles, the new strategies on the development of nanoparticle technology will be reviewed as shown in the following: Strategy 1: Determination of impurity and optimum size of nanoparticles. Determination of the optimum size and minimizing the impurities are key steps for the synthesis of best performance nanoparticles. Strategy 2: Selection and use of environmental‐friendly materials. Consideration on the cheap materials having high performance is inevitable. Strategy 3: Consideration on nanoparticles health effect (nanorisk). Design of particles in submicron‐sized having nanoparticles properties (e.g. nanostructured or nanocomposite) will be desirable. Detoxification operation becomes important. Strategy 4: Optimization of synthesis process, including nanoparticles nucleation, growth, transport, deposition, and sintering is important aspects for reactor design. In addition, the nanoparticles dispersion using beads mill with very small media would be essential for nanocomposite preparation process. Strategy 5: Micro‐controlled composite particles. Micro‐controlled composite particles for multi‐ purpose application is important, especially in medical application. Our recent researches will be introduced based on the above strategies.
Evaluation of GPR50, hMel-1B, and ROR-α Melatonin-related Receptors and the Etiology of Adolescent Idiopathic Scoliosis (2010)

This investigation is a genetic testing of the remaining currently known melatonin-related receptors that have not been analyzed earlier for association with AIS. Given the support in the literature of a relationship between melatonin and AIS, we have shown no mutations in any of the known melatonin-related receptor in patients with AIS.
Portal Hypertensive Gastropathy and Gastric Vascular Ectasia (2017)

Although portal hypertensive gastropathy (PHG) and gastric vascular ectasia (GVE) associated with portal hypertension share overlapping endoscopic features, their differences in management underline the relevance of distinguishing between these two entities. At endoscopy, PHG is identified by a snakeskin (mosaic) mucosal background, with or without pigmented spots, involving predominantly the proximal stomach. In contrast, GVE is characterized by flat or raised angioectatic red spots distributed primarily in the distal stomach, without the mosaic mucosal pattern. When symptomatic, chronic gastrointestinal bleeding is the most common manifestation for both conditions. For PHG, endoscopic management is of limited value and the mainstay of therapy involves measures aimed at lowering portal pressure, namely through the utilization of non-selective beta-blockers. On the other hand, endoscopic therapy is considered the primary treatment modality for GVE. Although argon plasma coagulation is the most commonly used technique for ablation of GVE, alternative treatment modalities include endoscopic band ligation, cryotherapy, and radiofrequency ablation.
Metal Phosphides: From Chemist's Oddities to Designed Functional Materials (2012)

This chapter contains sections titled: Introduction Bulk Metal Phosphides: A Long History White Phosphorus for the Low-Temperature Synthesis of Metal Phosphide Nanoparticles References
mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function (2018)

Cells respond to iron deficiency by activating iron-regulatory proteins to increase cellular iron uptake and availability. However, it is not clear how cells adapt to conditions when cellular iron uptake does not fully match iron demand. Here, we show that the mRNA-binding protein tristetraprolin (TTP) is induced by iron deficiency and degrades mRNAs of mitochondrial Fe/S-cluster-containing proteins, specifically <i>Ndufs1</i> in complex I and <i>Uqcrfs1</i> in complex III, to match the decrease in Fe/S-cluster availability. In the absence of TTP, <i>Uqcrfs1</i> levels are not decreased in iron deficiency, resulting in nonfunctional complex III, electron leakage, and oxidative damage. Mice with deletion of <i>Ttp</i> display cardiac dysfunction with iron deficiency, demonstrating that TTP is necessary for maintaining cardiac function in the setting of low cellular iron. Altogether, our results describe a pathway that is activated in iron deficiency to regulate mitochondrial function to match the availability of Fe/S clusters.
Spinal cord stimulation for the restoration of bladder function after spinal cord injury (2020)

Spinal cord injury (SCI) results in the inability to empty the bladder voluntarily, and neurogenic detrusor overactivity (NDO) and detrusor sphincter dyssynergia (DSD) negatively impact both the health and quality of life of persons with SCI. Current approaches to treat bladder dysfunction in persons with SCI, including self-catheterisation and anticholinergic medications, are inadequate, and novel approaches are required to restore continence with increased bladder capacity, as well as to provide predictable and efficient on-demand voiding. Improvements in bladder function following SCI have been documented using a number of different modalities of spinal cord stimulation (SCS) in both persons with SCI and animal models, including SCS alone or SCS with concomitant activity-based training. Improvements include increased volitional voiding, voided volumes, bladder capacity, and quality of life, as well as decreases in NDO and DSD. Further, SCS is a well-developed therapy for chronic pain, and existing Food And Drug Administration (FDA)-approved devices provide a clear pathway to sustainable commercial availability and impact. However, the effective stimulation parameters and the appropriate timing and location of stimulation for SCS-mediated restoration of bladder function require further study, and studies are needed to determine underlying mechanisms of action.
Xenoservers: accountable execution of untrusted programs (2003)

Many networked applications could benefit from executing closer to the data or services with which they interact. By doing this they may be able to circumvent long communication latencies or avoid transferring data over congested or expensive network links. However no public infrastructure currently exists that enables this. We propose a system that can execute code supplied by an untrusted user yet can charge this user for all resources consumed by the computation. Such servers could be deployed at strategic locations throughout the Internet, enabling network users such as content providers to distribute components of their applications in a manner that is both efficient and economical. We call such a server a Xenoserver. This paper discusses the construction of such a system, examining how accounting, billing, and quality of service provision can be achieved.
Definition of Distinct Compartments in Polarized Madin–Darby Canine Kidney (MDCK) Cells for Membrane‐Volume Sorting, Polarized Sorting and Apical Recycling (2000)

Previous studies of fibroblasts have demonstrated that recycling of endocytic receptors occurs through a default mechanism of membrane-volume sorting. Epithelial cells require an additional level of polar membrane sorting, but there are conflicting models of polar sorting, some suggesting that it occurs in early endosomes, others suggesting it occurs in a specialized apical recycling endosome (ARE). The relationship between endocytic sorting to the lysosomal, recycling and transcytotic pathways in polarized cells was addressed by characterizing the endocytic itineraries of LDL, transferrin (Tf) and IgA, respectively, in polarized Madin-Darby canine kidney (MDCK) cells. Quantitative analyses of 3-dimensional images of living and fixed polarized cells demonstrate that endocytic sorting occurs sequentially. Initially internalized into lateral sorting endosomes, Tf and IgA are jointly sorted from LDL into apical and medical recycling endosomes, in a manner consistent with default sorting of membrane from volume. While Tf is recycled to the basolateral membrane from recycling endosomes, IgA is sorted to the ARE prior to apical delivery. Quantifications of the efficiency of sorting of IgA from Tf between the recycling endosomes and the ARE match biochemical measurements of transepithelial protein transport, indicating that all polar sorting occurs in this step. Unlike fibroblasts, rab11 is not associated with Tf recycling compartments in either polarized or glass-grown MDCK cells, rather it is associated with the compartments to which IgA is directed after sorting from Tf. These results complicate a suggested homology between the ARE and the fibroblast perinuclear recycling compartment and provide a framework that justifies previous conflicting models of polarized sorting.
Edge-induced reliability & performance degradation in STT-MRAM: an etch engineering solution (2021)

To enable high density STT-MRAM, process-induced damage needs to be minimized. High temperature anneals and patterning can degrade performance and reliability. By employing a novel patterning scheme, involving physical ion beam etch, etchback and oxidation steps, we minimize the etch-induced damage and limit the oxygen penetration to the free layer, which can degrade device performance. Moreover, we demonstrate better magnetic properties, lower switching voltages and an improved reliability window. We establish BEOL compatibility with a 3-hour, 400°C anneal at the end-of-line and study scaled MTJ arrays with physical diameter of 50 nm.
Double infections with hepatitis A and B viruses (1985)

Ten (2.8%) asymptomatic carriers of HBsAg and four (1.1%) patients with acute hepatitis B virus (HBV) infection were detected among 356 adults with acute viral hepatitis A (HAV) consecutively admitted to the Athens Hospital for Infectious Diseases from May 1981 to March 1984. These patients did not differ in clinical, epidemiologic (except in age), biochemical or serologic characteristics from patients acutely infected with HAV alone. Transient suppression of the HBV replication and disappearance of the HBV DNA accompanied by seroconversion from HBeAg positive to anti-HBe positive were detected in one and two carriers respectively. The titer of non-class-specific anti-HBc was low (less than or equal to 10(-2)) in all cases. These data suggest that superinfection of HBsAg carriers with HAV does not cause more severe disease or influence adversely the course of chronic hepatitis B disease. However, accurate diagnosis of double infections is necessary for prognosis of the liver disease and appropriate management of the patient's environment. This is quite important in areas with a high prevalence of HBV infections, like Greece, where double infections are relatively common.
Abstract 3328: Protochadherin 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis (2017)

Abstract Non-small cell lung cancer (NSCLC) is the leading cause of cancer-associated deaths worldwide. Given the efficacy of membrane proteins as therapeutic targets in human malignancies, we examined cell-surface receptors that may act as drivers of lung tumorigenesis. Here we report that Protocadherin 7 (PCDH7), a transmembrane receptor and member of the Cadherin superfamily, is frequently overexpressed in NSCLC tumors, and high expression of PCDH7 is associated with poor clinical outcome. PCDH7 overexpression synergizes with KRAS and EGFR to induce MAPK signaling and tumorigenesis. Conversely, PCDH7 depletion suppresses ERK activation, sensitizes cells to MEK inhibitors, and reduces tumor growth. PCDH7 potentiates ERK signaling by facilitating interaction of protein phosphatase PP2A with its potent inhibitor, the SET oncoprotein. By establishing a previously unanticipated oncogenic role for PCDH7 in lung tumorigenesis, these results provide proof-of-concept support for the development of novel therapies that target PCDH7 at the cell surface of NSCLC cells. Experiments to evaluate the role of Pcdh7 in Kras-mediated lung tumorigenesis in vivo using autochthonous mouse models, which we expect to lend further support for therapeutic targeting of this protein, are in progress. Citation Format: Xiaorong Zhou, Barrett L. Updegraff, Yabin Guo, Michael Peyton, Luc Girard, Jill E. Larsen, Xian-Jin Xie, Yunyun Zhou, Tae Hyun Hwang, Yang Xie, Jaime Rodriguez-Canales, Pamela Villalobos, Carmen Behrens, Wistuba I. Ignacio, John D. Minna, Kathryn A. O'Donnell. Protochadherin 7 acts through SET and PP2A to potentiate MAPK signaling by EGFR and KRAS during lung tumorigenesis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 3328. doi:10.1158/1538-7445.AM2017-3328
The Effect of a Condylar Repositioning Plate on Condylar Position and Relapse in Two-Jaw Surgery (2017)

Background Numerous condylar repositioning methods have been reported. However, most of them are 2-dimensional or are complex procedures that require a longer operation time and a highly trained surgeon. This study aims to introduce a new technique using a condylar repositioning plate and a centric relation splint to achieve a centric relationship. Methods We evaluated 387 patients who had undergone surgery for skeletal jaw deformities. During the operation, a centric relation splint, intermediate splint, final centric occlusion splint, and condylar repositioning plate along with an L-type mini-plate for LeFort I osteotomy or a bicortical screw for bilateral sagittal split ramus osteotomy were utilized for rigid fixation. The evaluation included: a physical examination to detect preoperative and postoperative temporomandibular joint dysfunction, 3-dimensional computed tomography and oblique transcranial temporomandibular joint radiography to measure 3-dimensional condylar head movement, and posteroanterior and lateral cephalometric radiography to measure the preoperative and postoperative movement of the bony segment and relapse rate. Results A 0.3% relapse rate was observed in the coronal plane, and a 2.8% relapse rate in the sagittal plane, which is indistinguishable from the dental relapse rate in orthodontic treatment. The condylar repositioning plate could not fully prevent movement of the condylar head, but the relapse rate was minimal, implying that the movement of the condylar head was within tolerable limits. Conclusions Our condylar repositioning method using a centric relation splint and mini-plate in orthognathic surgery was found to be simple and effective for patients suffering from skeletal jaw deformities.
MEMS fingerprint sensor with arrayed cavity structures (2002)

We propose a MEMS (Micro Electro Mechanical Systems) fingerprint sensor whose pixels have novel cavity structures. Each cavity structure has a sensitive plane of a thin film on top, and a sensing circuit below it. Ridges on a finger surface bend the thin film mechanically, which is detected by the sensing circuit electronically. We fabricated the sensor using a CMOS compatible process with our sealing technique. The sensor can obtain fingerprint images of even dry or wet fingers. It also shows sufficient mechanical strength against finger pressure. These results confirm that the MEMS fingerprint sensor has the potential for wide practical application.
Hydrodynamic benefits of protruding eyes and mouth in a self-propelled flexible stingray (2021)

The hydrodynamic benefits of the protruding eyes and mouth (e&amp;m) of a stingray's smooth body are explored using the penalty immersed boundary method. A self-propelled flexible plate was realized in the present study; a clamped leading edge of the flexible plate was forced into a prescribed harmonic oscillation in the vertical direction but was free to move in the horizontal direction. The e&amp;m was formulated by the superposition of several rigid plates. Simulations without the e&amp;m were also performed for comparison. The pressure distributions and vortical structures around the flexible plate were visualized to characterize the hydrodynamic roles of the e&amp;m. The streamwise and spanwise vortices generated by the e&amp;m function together enhance the average cruising speed and thrust, where the streamwise vortices enhance the negative pressure at the leading edge of the flexible plate and the spanwise vortices increase the pressure difference between the upper and lower sides of the plate. A parametric study was performed to find an optimal shape of the e&amp;m that maximizes the average cruising speed (U¯c) and propulsion efficiency (η) as a function of the spanwise width. The presence of the e&amp;m increased the U¯c and η by more than 20.5% and 10.6%, respectively.
Swift Package Management (2017)

This chapter explores each aspect of the Swift package management ecosystem, including Swift Package Manager and the Swift Package Catalog. The concept of package management has been around for a while. The number of ?les on a computer system can be so numerous that it can be dif?cult to manage ?les individually. A package encapsulates multiple ?les into a more manageable chunk. Swift Package Manager is the Swift solution for package management. It supports the key capabilities we've discussed so far, such as dependency management and versioning. Swift Package Manager also has some useful features for systems programming, including specifying system modules and integration with C modules. The Swift Package Catalog has a robust search engine that indexes the package name, author organization, URL, and more, to return relevant search results. The dependencies graph is a very helpful way to see the relationship between a package and its dependencies.
Novel Mannich Ketones of Oxazolidinones as Antibacterial Agents. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.