gebhart/patrepeval huggingface dataset:
Physicists in a World of Wireless Communications: A Noisy Connection? [Industry Activities] (2022)

Welcome to this edition of the “Industry Activities” column. This month, we have the pleasure reading a contribution authored by Geoffroy Lerosey and Mathias Fink, which provides interesting insight into the challenges of starting a company based on ideas that are not considered “mainstream” in terms of conventional wireless engineering. One of the great lessons for any engineer is to be open minded: a concept is not wrong simply because it is difficult to understand. I am sure we have all had trouble with this during discussions with researchers and engineers who have different backgrounds and training. However cross-disciplinary ideas are extremely important for technology advancement.
syGlass: Interactive Exploration of Multidimensional Images Using Virtual Reality Head-mounted Displays (2018)

The quest for deeper understanding of biological systems has driven the acquisition of increasingly larger multidimensional image datasets. Inspecting and manipulating data of this complexity is very challenging in traditional visualization systems. We developed syGlass, a software package capable of visualizing large scale volumetric data with inexpensive virtual reality head-mounted display technology. This allows leveraging stereoscopic vision to significantly improve perception of complex 3D structures, and provides immersive interaction with data directly in 3D. We accomplished this by developing highly optimized data flow and volume rendering pipelines, tested on datasets up to 16TB in size, as well as tools available in a virtual reality GUI to support advanced data exploration, annotation, and cataloguing.
Knowledge Driven Image Mining with Mixture Density Mercer Kernals (2004)

This paper presents a new methodology for automatic knowledge driven image mining based on the theory of Mercer Kernels, which are highly nonlinear symmetric positive definite mappings from the original image space to a very high, possibly infinite dimensional feature space. In that high dimensional feature space, linear clustering, prediction, and classification algorithms can be applied and the results can be mapped back down to the original image space. Thus, highly nonlinear structure in the image can be recovered through the use of well-known linear mathematics in the feature space. This process has a number of advantages over traditional methods in that it allows for nonlinear interactions to be modelled with only a marginal increase in computational costs. In this paper we present the theory of Mercer Kernels; describe its use in image mining, discuss a new method to generate Mercer Kernels directly from data, and compare the results with existing algorithms on data from the MODIS (Moderate Resolution Spectral Radiometer) instrument taken over the Arctic region. We also discuss the potential application of these methods on the Intelligent Archive, a NASA initiative for developing a tagged image data warehouse for the Earth Sciences.
A Crushing Load of COVID-19 at Maharashtra: Indian Epicenter of the SARS-CoV-2 Pandemic (2020)

Medical clinics are overpowered with the devastating heap of COVID-19 cases and are experiencing deficiencies of individual defensive gear (Personal Protective Equipment) for care suppliers.More than 67,000 Indians have affected with COVID-19 till date, out of which 20,917 have been recovered with more than 2,206 of them are died.22,171 cases overview from Maharashtra state alone out of which 832 have lost their life and remaining are under treatment and sent for quarantine (Figure 1).Since late-April, either by choice or in response to shelter-in-place orders,
Effects of Intraduodenal Infusion of the Bitter Tastant, Quinine, on Antropyloroduodenal Motility, Plasma Cholecystokinin, and Energy Intake in Healthy Men (2019)

Quinine, administered intraduodenally over 60 minutes, even at moderately high doses, but low infusion rates, does not modulate appetite-related gastrointestinal functions or energy intake.
From Phenylthiazoles to Phenylpyrazoles: Broadening the Antibacterial Spectrum toward Carbapenem-Resistant Bacteria (2019)

The narrow antibacterial spectrum of phenylthiazole antibiotics was expanded by replacing central thiazole with a pyrazole ring while maintaining its other pharmacophoric features. The most promising derivative, compound <b>23</b>, was more potent than vancomycin against multidrug-resistant Gram-positive clinical isolates, including vancomycin- and linezolid-resistant methicillin-resistant <i>Staphylococcus aureus (</i>MRSA), with a minimum inhibitory concentration (MIC) value as low as 0.5 μg/mL. Moreover, compound <b>23</b> was superior to imipenem and meropenem against highly pathogenic carbapenem-resistant strains, such as <i>Acinetobacter baumannii</i>, <i>Klebsiella pneumoniae,</i> and <i>Escherichia coli</i>. In addition to the notable biofilm inhibition activity, compound <b>23</b> outperformed both vancomycin and kanamycin in reducing the intracellular burden of both Gram-positive and Gram-negative pathogenic bacteria. Compound <b>23</b> cleared 90% of intracellular MRSA and 98% of <i>Salmonella enteritidis</i> at 2× the MIC. Moreover, preliminary pharmacokinetic investigations indicated that this class of novel antibacterial compounds is highly metabolically stable with a biological half-life of 10.5 h, suggesting a once-daily dosing regimen.
Directional flank spreading at Mount Cameroon volcano: Evidence from analogue modeling (2014)

Abstract Mount Cameroon is characterized by an elongated summit plateau, steep flanks, and topographic terraces around its base. Although some of these features can be accounted for by intrusion‐induced deformation, we here focus on the contribution of edifice‐scale gravitational spreading in the structure of Mount Cameroon. We review the existing geological and geophysical data and morphostructural features of Mount Cameroon and surrounding sedimentary basins. Volcanic ridge gravitational spreading is then simulated by scaled analogue models on which fault formation is recorded using digital image correlation. Three sets of models are presented (i) models recorded in cross section (Type I), (ii) models recorded from above with a uniform (Type IIa), and (iii) nonuniform ductile layer (Type IIb). Type I models illustrate the formation of faults accommodating summit subsidence and lower flank spreading. Type IIa models favor displacement perpendicular to the long axis, with formation of a summit graben and basal folds, but fail to reproduce the steep flanks. Type IIb models investigate the effect of spatial variations in sediment thickness and/or properties consistent with geological evidence. Directional spreading of the volcano's central part perpendicular to the long axis is accounted for by a sediment layer with restricted lateral extent and increasing thickness away from the volcano axis. The later model closely reproduces key features observed at Mount Cameroon: steep upper flanks are accounted for by enhanced lateral spreading of the lower flanks relative to the summit. The relevance of these findings for understanding flank instabilities at large oceanic volcanoes is finally highlighted.
Structural aspects of the ambient-pressure BEDT-TTF superconductors (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural aspects of the ambient-pressure BEDT-TTF superconductorsHideki Yamochi, Tokutaro Komatsu, Nozomu Matsukawa, Gunzi Saito, Takehiko Mori, Masami Kusunoki, and Kenichi SakaguchiCite this: J. Am. Chem. Soc. 1993, 115, 24, 11319–11327Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/ja00077a034https://doi.org/10.1021/ja00077a034research-articleACS PublicationsRequest reuse permissionsArticle Views420Altmetric-Citations97LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Frequency Domain Long-Term Prediction for Low Delay General Audio Coding (2021)

In this paper we propose a long-term prediction method for low delay transform domain general audio coders. This Frequency Domain Joint Harmonics Prediction (FDJHP) method operates directly in the Modified Discrete Cosine Transform (MDCT) domain and can enhance the coding efficiency, even under very low frequency resolutions. We compare this new method with state-of-the-art MDCT based methods by analyzing bitrate savings and by a listening test using test signals with strong harmonic components. The results indicate that it outperforms an existing method, which also directly operates in the frequency domain. Additionally, we show how it can be combined with the existing techniques into an adaptive system, where the different methods can complement each other.
Successful implantation of an active transcutaneous bone conduction implant system in children under 5 years (2022)

Introduction The Bonebridge system is a transcutaneous bone conduction implant system for patients with conductive and mixed hearing loss. Younger children with a lesser bone thickness were previously mainly treated with a percutaneous osseointegrated bone-anchored hearing aid (BAHA) or a middle-ear implant. While the BAHA with its percutaneous screw increases the risk of implant infections or involvement of the implant in head trauma, middle-ear implant surgery involves manipulation of the ossicles with possible risk of surgical trauma and implant displacement. These complications can be omitted with transcutaneous bone conduction implant systems. The second generation of the Bonebridge (BCI 602) features a decreased thickness of the floating mass trancducer with reduced drilling depth and can thus be implanted in younger children.
Analysis of the 5:1 Dipole Benchmark Case Using the Current-Model Method with an SVD-Improved Point Matching Technique (1993)

The 5:1 dipole benchmark case has been analyzed extensively by many researchers using different codes based on various numerical techniques. In this paper this benchmark case is solved by the current-model method in which the fulfillment of the boundary condition is improved using the singular value decomposition (SVD) of the moment matrix. The SVD is the most informative general representation of a matrix and its use in the current-model method improves the stability as well as the accuracy of the numerical solution. Its application results in a considerable reduction of the boundary condition errors between the matching points. Obviously, the boundary condition errors at the matching points are no longer strictly zero, but acceptably low values are retained. Comparisons between the results obtained using the various techniques are presented. It is shown that the difference between Ludwig's results, which are based on a spherical-wave expansion approach, and ours is within the error estimate characterizing the former results accuracy.
Design of Polyphosphazene Hydrogels with Improved Structural Properties by Use of Star‐Shaped Multithiol Crosslinkers (2011)

The feasibility of using a star-shaped crosslinker to produce a hydrogel with controlled mechanical properties and degradation rates was investigated. The aqueous blends of functional polymers and crosslinkers formed a solution at low temperature and a hydrogel with desired mechanical properties at body temperature. The introduction of star-shaped crosslinkers affected the microscopic and macroscopic properties of the hydrogel. The fabricated hydrogels could be suitable for many potential biomedical applications because of their injectability, tunable mechanical properties, controlled degradation rate and gel formation under physiological conditions.
IL-10 Is Critical in the Regulation of Autoimmune Encephalomyelitis as Demonstrated by Studies of IL-10- and IL-4-Deficient and Transgenic Mice (1998)

Experimental autoimmune encephalomyelitis (EAE) and other organ-specific autoimmune diseases are induced by autoantigen-specific Th1 cells. In contrast, transfer of autoantigen-reactive Th2 cells that produce IL-4 and IL-10 can prevent and/or reverse EAE. The relative roles of these two Th2 cytokines in the regulation of EAE has not been evaluated. Utilizing IL-4 and IL-10 knockout mice deficient for these cytokines and IL-10 and IL-4 transgenic mice overexpressing these cytokines, we demonstrate that IL-10-deficient mice (IL-10(-/-)) are more susceptible and develop a more severe EAE when compared with IL-4-deficient mice (IL-4(-/-)) or wild-type mice. T cells from IL-10(-/-) mice exhibit a stronger Ag-specific proliferation, produce more proinflammatory cytokines (IFN-gamma and TNF-alpha) when stimulated with an encephalitogenic peptide, and induce very severe EAE upon transfer into wild-type mice. In contrast, while IL-4 transgenic mice develop similar disease compared with their nontransgenic littermates, mice transgenic for IL-10 are completely resistant to the development of EAE. Taken together, our data suggest that IL-10 plays a more critical role in the regulation of EAE by regulating autopathogenic Th1 responses.
SCUBE1 Controls BMPR2-Relevant Pulmonary Endothelial Function (2020)

Utilizing publicly available ribonucleic acid sequencing data, we identified SCUBE1 as a BMPR2-related gene differentially expressed between induced pluripotent stem cell-endothelial cells derived from pulmonary arterial hypertension (PAH) patients carrying pathogenic BMPR2 mutations and control patients without mutations. Endothelial SCUBE1 expression was decreased by known triggers of PAH, and its down-regulation recapitulated known BMPR2-associated endothelial pathophenotypes in vitro. Meanwhile, SCUBE1 concentrations were reduced in plasma obtained from PAH rodent models and patients with PAH, whereas plasma concentrations were tightly correlated with hemodynamic markers of disease severity. Taken together, these data implicate SCUBE1 as a novel contributor to PAH pathogenesis with potential therapeutic, diagnostic, and prognostic applications.
BCR-ABL1 compound mutants display differential and dose-dependent responses to ponatinib (2017)

The third-generation tyrosine kinase inhibitor (TKI) ponatinib exerts a strong anti-neoplastic effect in all stages of chronic myeloid leukemia (CML) as well as in Philadelphia(Ph)-positive acute lymphoblastic leukemia (ALL). It is capable of suppressing the kinase activity of BCR-ABL1 carrying any
Development of a novel sensing probe using DNA aptamer inhibiting enzymatic activity (2005)

A novel sensing probe for adenosine has been developed using the thrombin-inhibiting DNA aptamer fused with the adenosine-binding DNA aptamer. The adenosine aptamer was inserted into the G-quartet structure of the thrombin aptamer to change its inhibitory activity to thrombin upon binding of the adenosine aptamer part to adenosine. This designed aptamer had lower inhibitory activity than that of the original thrombin aptamer, and it was increased in the presence of adenosine. CD spectra of this designed aptamer indicated that its structure was changed by its binding to adenosine. Using this designed aptamer, we were able to detect adenosine by measuring thrombin activity in homogeneous assay.
Frequent baked egg ingestion was not associated with change in rate of decline in egg skin prick test in children with challenge confirmed egg allergy (2012)

Given that dietary restrictions can adversely impact on the family, it is reasonable to consider liberalizing baked egg in the diet of egg-allergic children.
Solution Processed Oxide Thin Film Transistors (2014)

We have developed thin-film-transistors (TFTs) manufactured by a solution processing of the gate insulators and the active material. Oxide insulators, such as aluminum oxide, hafnium oxide, or zirconium doped aluminum oxide represent a method to achieve high performance and low power consuming TFTs. Along with amorphous indium gallium zinc oxide ( a-IGZO), other oxide semiconductors have been studied. Solution processing offers the opportunity to test various materials quickly with low capital investment. We studied poly-crystalline materials, such as indium oxide (In 2 O 3 ), and tin oxide (SnO 2 ), or amorphous oxides such as indium zinc tin oxide (IZTO). We have developed inket-printed TFTs at the maximum process temperature of 300 o C. Inkjet-printed polycrystalline InOx TFTs have mobilities of 60cm 2 /Vs, and were used in unipolar inverters. SnOx TFTs, show a dependence on the solution concentration, and the mobility can reach ~70cm 2 /Vs. On the other hand, amorphous IZTO TFTs showed the highest mobility of ~100cm 2 /Vs by the careful control of the inkjet process. References C. Avis and J. Jang, J. Mater. Chem. , 21 , 10649-10652, 2011 C. Avis and J. Jang, Jap. J. Appl. Phys., 2011, 50 , 01BG03, 2011 C. Avis and Jin Jang, Electrochem. Solid-State Lett. , 4 , J9-J11, , 2011 Y. G. Kim, C. Avis and J. Jang, ECS Solid-State Lett. , 1 , Q23-Q25, 2012 C. Avis, Y. G. Kim, and J. Jang, J. Mater. Chem. , 22 , 17415–17420, 2012 Y. G. Kim, C. Avis, and J. Jang, J. Disp. Tech. , accepted, 2014 Figure 1: transfer characteristics of IZTO TFT.
Investigation of Conductivity and Ionic Transport of VO2(M) and VO2(R) via Electrochemical Study (2018)

Vanadium dioxides exist as a variety of polymorphs, each with differing structural and electrochemical capabilities. The monoclinic to rutile transition is an interesting system for study as the transition temperature is easily accessible at moderate temperature and corresponds to an increase in electrical conductivity by 2 orders of magnitude. The transition from monoclinic to rutile is characterized structurally herein using synchrotron-based X-ray diffraction and related to lithium-ion electrochemistry using electrochemical impedance spectroscopy and intermittent pulsatile galvanostatic discharge tests. The experimental results indicate a decrease in ohmic resistance for lithium-based cells tested under higher temperatures. Complementary density functional theory calculations described the experimentally measured intercalation voltages and identified a possible Li-induced LixVO2(M) to LixVO2(R) phase transition during the discharging process rationalizing the favorable impact on the function of a lithium-based electrochemical cell. To our knowledge, this is the first observation of the metal–insulator transition of VO2 in a full electrochemical cell.
Near Real-Time Prospecting for Lunar Volatiles: Demonstrating RESOLVE Science in the Field (2012)

The Regolith and Environment Science and Oxygen & Lunar Volatile Extraction (RESOLVE) project aims to demonstrate the utility of situ resource utilization. In situ resource utilization (ISRU) is a way to rebalance the economics of spaceflight by reducing or eliminating materials that must be brought up from Earth and placed on the surface of the Moon for human use. RESOLVE is developing a rover-borne payload that (1) can locate near subsurface volatiles, (2) excavate and analyze samples of the volatile-bearing regolith, and (3) demonstrate the form, extractability and usefulness of the materials. Such investigations are important not only for ISRU but are also critically important for understanding the scientific nature of these intriguing lunar polar volatile deposits. Temperature models and orbital data suggest near surface volatile concentrations may exist at briefly lit lunar polar locations outside persistently shadowed regions. A lunar rover could be remotely operated at some of these locations for the 4-7 days of expected sunlight at relatively low cost. In July 2012 the RESOLVE project conducted a full-scale field demonstration. In particular, the ability to perform the real-time measurement analysis necessary to search for volatiles and the ability to combine the various measurement techniques to meet the mission measurement and science goals. With help from the Pacific International Space Center for Exploration Systems (PISCES), a lunar rover prototype (provided by the Canadian Space Agency) was equipped with prospecting instruments (neutron spectrometer and near-infrared spectrometer), subsurface access and sampling tools, including both an auger and coring drill (provided by CSA) and subsurface sample analysis instrumentation, including a sample oven system, the Oxygen and Volatile Extraction Node (OVEN), and Gas Chromatograph / Mass Spectrometer system, the Lunar Advanced Volatile Analysis (LAVA) system. Given the relatively short time period this lunar mission is being designed to, prospecting needs to occur in near real-time. The two prospecting instruments are the neutron and NIR spectrometers. In the field demo a small radioactive source was provided the neutron flux. The NIR spectrometer, which includes its own light source, looks at surface reflectance for signatures of bound H20/0H and general mineralogy. Once a hot spot was found by the prospecting instruments, the drill could either auger or core. The auger drill worked to a depth of 50 cm and is monitored with a drill camera and the NIR spectrometer. As cuttings are brought up the NIR spectra is monitored. If a particular location is considered of high -interest then the decision to core could be made. The coring drill (a push-tube) allowed a meter sample to be acquired processed by the OVEN/LAVA sys-tem. This presentation will provide details as how these instruments worked together and how and if the planned measurements and science was obtained.