gebhart/patrepeval huggingface dataset:
Nanocrystalline Ba0.97Ca0.03SO4:Eu for ion beams dosimetry (2008)

Nanoparticles of Ba0.97Ca0.03SO4:Eu have been irradiated by 48 MeV Li3+, 75 MeV C6+, and 90 MeV O7+ ion beams with a fluence range of 1×109−1×1013 ion/cm2. The thermoluminescence (TL) glow curves along with the response curves of this nanophosphor have been investigated and compared with those of the corresponding microcrystalline samples. TL glow curve of the nanophosphor exposed to γ-rays has also been included in the letter with the aim of reporting some of the comparative measurements. The glow curves of the ion-beam irradiated nanomaterials are similar in their shapes to those induced by gamma rays, with a shift in the peak positions to the higher temperature side by around 30 K. The TL intensity of the ion-beam irradiated nanomaterials is found to decrease, while going from low to high atomic number (Z) ions (i.e., Li3+→O7+). Similar trend was also observed in the linearity of the TL response curves. The response curve of Li ion irradiated nanomaterials is sublinear in the whole range of studied fluences. C ion has also a more or less similar response, while the O ion has a sublinear response over a shorter range of 1×109−1×1012 ion/cm2, and above this range the response saturates. These results for the nanomaterials are much better than that of the corresponding microcrystalline sample irradiated by Li3+ ions. The curve was sublinear up to the fluence 1×1010 ion/cm2 and then saturates at higher fluences. The wider sublinear TL response of the nanocrystalline Ba0.97Ca0.03SO4:Eu makes it superior to its corresponding microform and thus makes it a suitable candidate as a dosimeter to be used for detecting the doses of ions, especially the Li and C ions for their application in cancer radiotherapy and radiation biology.
Telomere Length Changes in Children With Cushing Disease: A Pilot Study (2020)

In this pilot study, TL is shorter in children with hypercortisolemia, a difference that becomes detectable only after cure of CD. Triglycerides and blood pressure appear to be factors that are associated with TL in these patients. Further studies are required to confirm these results.
H2O2-dependent substrate oxidation by an engineered diiron site in a bacterial hemerythrin (2014)

The O2-binding carboxylate-bridged diiron site in DcrH-Hr was engineered in an effort to perform the H2O2-dependent oxidation of external substrates. A His residue was introduced near the diiron site in place of a conserved residue, Ile119. The I119H variant promotes the oxidation of guaiacol and 1,4-cyclohexadiene upon addition of H2O2.
Ionic and electronic conductivities in carbon nanotubes – ionogel solid device (2010)

Easy immobilisation of carbon nanofillers in a solid state device featuring mesopores filled with ionic liquid (IL) is presented. Such a route allows a good dispersion of carbon nanotubes (CNTs) and carbon fibers in N-methyl-N-propylpyrrolidinium bis(trifluoromethanesulfonyl)imide, subsequently followed by the confinement of the whole within a porous silica matrix. We thus obtain herein a new type of hybrid ionogel within a solid device containing a percolating IL network as its real liquid state, as well as presenting a percolating carbon network. The process is carried out within a single step, without any chemistry for covalent grafting. We show that an IL with a non π-conjugated cation allows good dispersion of the carbon nanotubes, with a subsequent percolation for a loading level lower than 3.6 wt%. Together with the dynamic IL properties of ionogels, we thus present herein an inorganic-solid host containing carbon nanofillers, which gives the solid device ionic and electronic conductivities.
Defensive ML: Defending Architectural Side-channels with Adversarial Obfuscation (2023)

Side-channel attacks that use machine learning (ML) for signal analysis have become prominent threats to computer security, as ML models easily find patterns in signals. To address this problem, this paper explores using Adversarial Machine Learning (AML) methods as a defense at the computer architecture layer to obfuscate side channels. We call this approach Defensive ML, and the generator to obfuscate signals, defender. Defensive ML is a workflow to design, implement, train, and deploy defenders for different environments. First, we design a defender architecture given the physical characteristics and hardware constraints of the side-channel. Next, we use our DefenderGAN structure to train the defender. Finally, we apply defensive ML to thwart two side-channel attacks: one based on memory contention and the other on application power. The former uses a hardware defender with ns-level response time that attains a high level of security with half the performance impact of a traditional scheme; the latter uses a software defender with ms-level response time that provides better security than a traditional scheme with only 70% of its power overhead.
Potassium Molten Salt-Mediated In Situ Structural Reconstruction of a Carbon Nitride Photocatalyst (2023)

Metal-free polymeric carbon nitride (PCN) materials are at the forefront of photocatalytic applications. Nevertheless, the overall functionality and performance of bulk PCN are limited by rapid charge recombination, high chemical inertness, and inadequate surface-active sites. To address these, here, we employed potassium molten salts (K<sup>+</sup>X<sup>-</sup>, where X<sup>-</sup> is Cl<sup>-</sup>, Br<sup>-</sup>, and I<sup>-</sup>) as a template for the <i>in situ</i> generation of surface reactive sites in thermal pyrolyzed PCN. Theoretical calculations imply that addition of KX salts to PCN-forming monomers causes halogen ions to be doped into C or N sites of PCN with a relative trend of halogen ion doping being Cl < Br < I. The experimental results show that reconstructing C and N sites in PCN develops newer reactive sites that are beneficial for surface catalysis. Interestingly, the photocatalytic H<sub>2</sub>O<sub>2</sub> generation rate of KBr-modified PCN was 199.0 μmol h<sup>-1</sup>, about three times that of bulk PCN. Owing to the simple and straightforward approach, we expect molten salt-assisted synthesis to have wide exploration in modifying PCN photocatalytic activity.
1,5-α-d-Mannoseptanosides, Ring-Size Isomers That Are Impervious to α-Mannosidase-Catalyzed Hydrolysis (2009)

1,5-D-mannoseptanosyl di- and trisaccharide ring-size isomers of the corresponding mannopyranosyl oligosaccharides have been prepared. Remarkably, these compounds show no inhibition of the alpha-mannosidase-catalyzed hydrolysis of p-nitrophenyl-alpha-D-mannopyranoside.
Injection-locked semiconductor laser-based frequency comb for modulation applications in RF analog photonics (2016)

A linearized intensity modulator for periodic and pulsed light is proposed and demonstrated. The free carrier plasma effect has been used to modulate the refractive index of the phase section of a three-section mode-locked laser. If injection locked, the modulation induces an arcsine phase response on the three-section mode-locked laser. By introducing this mode-locked laser into a Mach-Zehnder interferometer biased at quadrature, one can realize a true linear intensity modulation. This novel laser suppresses any unwanted amplitude modulation and increases the performance of the linearized intensity modulator. Experimental results have provided a record low static I<sub>π</sub> of 0.39 mA and a spur-free dynamic range of 75 dB.Hz<sup>2/3</sup>.
Metalized Soft Polymers for Electromechanical Transducers on Glass Substrates (2021)

In this study, two different semiconductor-grade polymers are utilized to build up membrane-based electromechanical transducers. With three to four orders of magnitude lower modulus in comparison with silicon, the use of polymers as the vibrating membrane improves the mechanical output characteristics where larger vibration amplitude is needed. Novel processing methods, including an excimer laser-aided wafer-to-water transferring technique, have been developed for the introduction of polymers into the standard cleanroom fabrication environment. Both piezoelectric and electrostatic transducers are fabricated on glass substrates and then characterized with laser dropper velocimetry. Comparison is made to exemplify the advantages and disadvantages of using polymers with varied dynamic specifications for different applications, where the compromise between fabrication robustness and device performance is needed.
Evaluation Of A Score-Informed Source Separation System. (2010)

[TODO] Add abstract here.
Ibrutinib versus temsirolimus: 3-year follow-up of patients with previously treated mantle cell lymphoma from the phase 3, international, randomized, open-label RAY study (2018)

patients relapsing after first-generation novel agents is extremely poor
Model-driven experimental design workflow expands understanding of regulatory role of Nac in Escherichia coli (2023)

The establishment of experimental conditions for transcriptional regulator network (TRN) reconstruction in bacteria continues to be impeded by the limited knowledge of activating conditions for transcription factors (TFs). Here, we present a novel genome-scale model-driven workflow for designing experimental conditions, which optimally activate specific TFs. Our model-driven workflow was applied to elucidate transcriptional regulation under nitrogen limitation by Nac and NtrC, in <i>Escherichia coli</i>. We comprehensively predict alternative nitrogen sources, including cytosine and cytidine, which trigger differential activation of Nac using a model-driven workflow. In accordance with the prediction, genome-wide measurements with ChIP-exo and RNA-seq were performed. Integrative data analysis reveals that the Nac and NtrC regulons consist of 97 and 43 genes under alternative nitrogen conditions, respectively. Functional analysis of Nac at the transcriptional level showed that Nac directly down-regulates amino acid biosynthesis and restores expression of tricarboxylic acid (TCA) cycle genes to alleviate nitrogen-limiting stress. We also demonstrate that both TFs coherently modulate α-ketoglutarate accumulation stress due to nitrogen limitation by co-activating amino acid and diamine degradation pathways. A systems-biology approach provided a detailed and quantitative understanding of both TF's roles and how nitrogen and carbon metabolic networks respond complementarily to nitrogen-limiting stress.
Experimental methods for optimal tuning of bendable mirrors for diffraction-limited soft x-ray focusing (2013)

We report on hands-on experimental methods developed at the Advanced Light Source (ALS) for optimal tuning of mechanically bendable x-ray mirrors for diffraction-limited soft x-ray nano-focusing. For ex situ tuning of the benders for optimal beam-line performance, we use a revised version of the method of characteristic functions recently developed at the ALS optical metrology laboratory. At-wavelength optimal tuning of bendable optics consists of a series of wavefront-sensing tests with increasing accuracy and sensitivity, including modified scanning-slit Hartmann tests. The methods have been experimentally validated at ALS test beamline 5.3.1 and the micro-diffraction beamline 12.3.2 in applications to optimally set bendable Kirkpatrick-Baez mirrors designed for sub-micron focusing.
Fluorinated MOF platform for selective removal and sensing of SO2 from flue gas and air (2019)

Conventional SO<sub>2</sub> scrubbing agents, namely calcium oxide and zeolites, are often used to remove SO<sub>2</sub> using a strong or irreversible adsorption-based process. However, adsorbents capable of sensing and selectively capturing this toxic molecule in a reversible manner, with in-depth understanding of structure-property relationships, have been rarely explored. Here we report the selective removal and sensing of SO<sub>2</sub> using recently unveiled fluorinated metal-organic frameworks (MOFs). Mixed gas adsorption experiments were performed at low concentrations ranging from 250 p.p.m. to 7% of SO<sub>2</sub>. Direct mixed gas column breakthrough and/or column desorption experiments revealed an unprecedented SO<sub>2</sub> affinity for KAUST-7 (NbOFFIVE-1-Ni) and KAUST-8 (AlFFIVE-1-Ni) MOFs. Furthermore, MOF-coated quartz crystal microbalance transducers were used to develop sensors with the ability to detect SO<sub>2</sub> at low concentrations ranging from 25 to 500 p.p.m.
FCRL1 on chronic lymphocytic leukemia, hairy cell leukemia and B-cell non-Hodgkin's lymphoma as a target of immunotoxins (2007)

A55 FCRL1 (Fc receptor like 1) is a cell surface membrane protein that belongs to FCRL family and is preferentially expressed on B-cells. To evaluate FCRL1 as an immunotherapy target for B-cell malignancies, we prepared anti-FCRL1 mAbs with no cross-reactivity to other FCRL family proteins and analyzed FCRL1 protein expression on malignant cells from patient and on B-cell lines. Frequent FCRL1 protein expression was observed by flow cytometry on 12 B-cell non-Hodgkin9s lymphoma (B-NHL) cell lines and many patient samples: 12 of 14 chronic lymphocytic leukemia (CLL), 7 of 7 follicular lymphoma (FL), 13 of 17 hairy cell leukemia (HCL), and 2 of 3 mantle cell lymphoma (MCL). Two recombinant immunotoxins, E3(Fv)-PE38 and E9(Fv)-PE38, were constructed. Both immunotoxins bound to FCRL1 positive cells with similar affinities (3.4 and 3.2 nM) and were cytotoxic to cell lines, but E9(Fv)-PE38 was 4-20 fold more cytotoxic than E3(Fv)-PE38. The IC50s of E9(Fv)-PE38 on 11 different FCRL1 positive cell lines rang from 1.0 ng/ml to 90 ng/ml and correlate with the FCRL1 expression levels. Our results indicate that FcRL1 may serve as a good target for the immunotherapy of hematological diseases. Anti-FCRL1 immunotoxin E9(Fv)-PE38 exhibits remarkably specific cytotoxicity and merits further evaluation for the treatment of FCRL1 positive malignancies, including CLL, HCL, FL, MCL, and other B-NHL.
Characteristics of the getter materials used in High Intensity Discharge Lamps (2006)

In the field of discharge lamps many efforts are focused on improving qualities and performances of the devices. It is well known that gaseous impurities, possibly present inside the burner and inside the outer bulb of high intensity discharge (HID) lamps, are one of the main causes of the deterioration of their performances. Usually getter materials are adopted to absorb the gaseous impurities that may be generated by the residues of lamp fabrication process or that are released during lamp operation. These can be efficiently removed by means of a simple getter component, so as to create and maintain the very clean atmosphere necessary to assure high quality characteristics of the lamp for all its life. Getters are used in HID lamps with outer bulbs both under vacuum and with nitrogen atmosphere; in this second type of lamps it is necessary that the getter works properly without being affected by, or interfering with, the jacket filling gas. The getter material must be able to sorb various gaseous species generated inside the lamp envelope, such as hydrogen, water vapour, carbon monoxide and hydrocarbons. In this paper we have presented and discussed properties and sorption characteristics of the main getter materials adopted in HID lamps, such as the Zr-Al, Zr-Fe and Zr-Co-rare earths alloys. The sorption performances of the materials were measured in experimental systems simulating possible lamp conditions. Experiments were carried out to study the ability of the materials to capture hydrogen that is the most deleterious gaseous contaminant in discharge lamps. Moreover, in order to understand the complex sorption mechanisms that take place on the getters when different gaseous impurities are coexisting inside the lamps, specific tests were performed to determine the simultaneous sorption of different gas species, such as sorption of hydrogen and nitrogen, hydrogen and carbon monoxide, hydrogen and carbon dioxide
A Microfluidic Device Combining Dielectrophoresis and Field Flow Fractionation for Particle and Cell Discrimination (1998)

The technique of dielectrophoretic field flow fractionation (DEP/FFF) is described and a microfluidic device incorporating this principle is demonstrated. In operation, the device positions particles within a pressure-driven hydrodynamic flow profile by dielectrophoretic levitation according to their dielectric properties. Particles having different dielectric properties are differentially levitated and transported at different rates thereby separating them.
Dynamic Nuclear Polarization‐Enhanced Biomolecular NMR Spectroscopy at High Magnetic Field with Fast Magic‐Angle Spinning (2018)

Abstract Dynamic nuclear polarization (DNP) is a powerful way to overcome the sensitivity limitation of magic‐angle‐spinning (MAS) NMR experiments. However, the resolution of the DNP NMR spectra of proteins is compromised by severe line broadening associated with the necessity to perform experiments at cryogenic temperatures and in the presence of paramagnetic radicals. High‐quality DNP‐enhanced NMR spectra of the Acinetobacter phage 205 (AP205) nucleocapsid can be obtained by combining high magnetic field (800 MHz) and fast MAS (40 kHz). These conditions yield enhanced resolution and long coherence lifetimes allowing the acquisition of resolved 2D correlation spectra and of previously unfeasible scalar‐based experiments. This enables the assignment of aromatic resonances of the AP205 coat protein and its packaged RNA, as well as the detection of long‐range contacts, which are not observed at room temperature, opening new possibilities for structure determination.
Supplementary Figure S3 from Hemolytic <i>E. coli</i> Promotes Colonic Tumorigenesis in Females (2023)

&lt;p&gt;Requirement of FimH for colonization of hly+ type 1-E. coli in the colon of mice. (A) Colonization and persistence of J47, J47Î"hly and J47Î"fimH in the colon of wild-type BALB/c mice, as revealed by the number of the fed bacteria in stools. The bacteria number was determined by counting colony forming units (CFU). (B) Colonization of J47 and J47Î"hly in colonic mucosa of mice as revealed by percentage of the fed bacteria in total mucosa E. coli. ns, not significantly different; *P &lt; 0.05; **P &lt; 0.01.&lt;/p&gt;
GLINT: GlucoCEST in neoplastic tumors at 3 T – preliminary application in glioma patients using optimized preparation, imaging, and post-processing (2019)

Dynamic glucoCEST at clinical field strengths is very challenging due to the low effect size. Here, we present a saturation, imaging and post-processing protocol for minimizing possible artifacts to detect dynamic CEST effects reliably, and demonstrate the application in two glioblastoma patients at 3 T.
Nonlinear Multi-Resonant Cavity Quantum Photonics Gyroscopes Quantum Light Navigation (2023)

We propose an on-chip all-optical gyroscope based on nonlinear multi-resonant cavity quantum photonics in thin film $χ^{(2)}$ resonators -- Quantum-Optic Nonlinear Gyro or QONG in short. The key feature of our gyroscope is co-arisal and co-accumulation of quantum correlations, nonlinear wave mixing and non-inertial signals, all inside the same sensor-resonator. We theoretically analyze the Fisher Information of our QONGs under fundamental quantum noise conditions. Using Bayesian optimization, we maximize the Fisher Information and show that $\sim 900\times$ improvement is possible over the shot-noise limited linear gyroscope with the same footprint, intrinsic quality factors and power budget.
ChemInform Abstract: rac‐[Methylene(3‐tert‐butyl‐1‐indenyl)2]ZrCl2: A Simple, High‐Performance Zirconocene Catalyst for Isotactic Polypropene. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Molecular cloning and sequencing of the cDNA and gene for a novel elastinolytic metalloproteinase from Aspergillus fumigatus and its expression in Escherichia coli (1994)

An extracellular elastinolytic metalloproteinase, purified from Aspergillus fumigatus isolated from an aspergillosis and patient/and an internal peptide derived from it were subjected to N-terminal sequencing. Oligonucleotide primers based on these sequences were used to PCR amplify a segment of the metalloproteinase cDNA, which was used as a probe to isolate the cDNA and gene for this enzyme. The gene sequence matched exactly with the cDNA sequence except for the four introns that interrupted the open reading frame. According to the deduced amino acid sequence, the metalloproteinase has a signal sequence and 227 additional amino acids preceding the sequence for the mature protein of 389 amino acids with a calculated molecular mass of 42 kDa, which is close to the size of the purified mature fungal proteinase. This sequence contains segments that matched both the N terminus of the mature protein and the internal peptide. A. fumigatus metalloproteinase contains some of the conserved zinc-binding and active-site motifs characteristic of metalloproteinases but shows no overall homology with known metalloproteinases. The cDNA of the mature protein when introduced into Escherichia coli directed the expression of a protein with a size, N-terminal sequence, and immunological cross-reactivity identical to those of the native fungal enzyme. Although the enzyme in the inclusion bodies could not be renatured, expression at 30 degrees C yielded soluble enzyme that showed chromatographic behavior identical to that of the native fungal enzyme and catalyzed hydrolysis of elastin. The metalloproteinase gene described here was not found in Aspergillus flavus.
Modeling Inertial Sensor Errors Using Autoregressive (AR) Models (2004)

ABSTRACT: The residual random errors of the inertial sensors of a strapdown inertial navigation system (SINS) may deteriorate the overall positioning accuracy. These errors are modeled stochastically and included in the SINS error model. A first-order Gauss-Markov (GM) model with large correlation time is usually used to describe the stochastic nature of these errors. However, if the autocorrelation sequences of these random components are examined, it can be determined that a first-order GM model is not adequate to describe such stochastic behavior. This paper offers an alternative method of modeling the inertial sensor random errors as an autoregressive (AR) process. Among the different techniques that can optimally determine the AR model parameters, Burg's method was able to provide the highest accuracy when applied to navigation-grade SINS. Considering the SINS AR model for each inertial sensor, the results showed a major improvement in positioning accuracy compared with the commonly used GM models.
Cross Enterprise Improvements Delivered via a Cloud Platform: A Game Changer for the Consumer Product and Retail Industry (2010)

Gaining visibility into their retail supply chain has become a top priority for the Consumer Product (CP) industry. However, taking a “do-it-yourself” approach to the problem is proving to be both expensive and complex. Cloud Computing, with its on-demand provisioning capability on shared resources, has emerged as a new paradigm to address the challenges of the CP industry. In this paper, we describe a framework for deployment of business analytic solutions on a Cloud platform. We illustrate the benefits of the approach in context of the Demand Driven Business Analytic solution that provides demand signals to CP manufacturers.
Supplementary Data from Neural Tumor-Initiating Cells Have Distinct Telomere Maintenance and Can be Safely Targeted for Telomerase Inhibition (2023)

&lt;p&gt;Supplementary Figures S1-S4.&lt;/p&gt;