gebhart/patrepeval huggingface dataset:
SeRLoc (2004)

In many applications of wireless sensor networks (WSN), sensors are deployed un-tethered in hostile environments. For location-aware WSN applications, it is essential to ensure that sensors can determine their location, even in the presence of malicious adversaries. In this paper we address the problem of enabling sensors of WSN to determine their location in an un-trusted environment. Since localization schemes based on distance estimation are expensive for the resource constrained sensors, we propose a range-independent localization algorithm called SeRLoc. SeRLoc is distributed algorithm and does not require any communication among sensors. In addition, we show that SeRLoc is robust against severe WSN attacks, such as the wormhole attack, the sybil attack and compromised sensors. To the best of our knowledge, ours is the first work that provides a security-aware range-independent localization scheme for WSN. We present a threat analysis and comparison of the performance of SeRLoc with state-of-the-art range-independent localization schemes.
Vapor phase treatment of CdTe/CdS thin films with CdCl/sub 2/:O/sub 2/ (1996)

A controllable technique for treating CdTe/CdS thin film structures to produce uniform film properties and device performance is presented. Heat treatments of physical vapor deposited CdTe/CdS thin films were carried out in an atmosphere containing CdCl/sub 2/ vapor and air, or mixtures of Ar and O/sub 2/. The heat treatment reactor permitted independent control over the reaction temperature and the CdCl/sub 2/ source temperature, hence CdCl/sub 2/ vapor phase concentration at the CdTe surface. Modelling of the thermal and mass transfer for the reactor geometry shows that at total pressure of 1 atmosphere of air, the CdCl/sub 2/ equilibrium concentration over the CdTe surface is established in less than 2 seconds and varies from 1.3 mtorr at 380/spl deg/C to 32.7 mtorr at 450/spl deg/C. The effects of treatment conditions on interdiffusion, grain coalescence, and device operation are presented. Devices with efficiency greater than 11% were obtained for treatment with a CdCl/sub 2/ partial pressure of 9 mtorr in the temperature range 420-430/spl deg/C and at oxygen partial pressures from 8 mtorr to 570 torr.
Na+-Glucose Cotransporter Inhibitors as Antidiabetics. I. Synthesis and Pharmacological Properties of 4'-Dehydroxyphlorizin Derivatives Based on a New Concept. (1996)

Based on our new concept that inhibitors of the Na(+)-glucose cotransporter (SGLT) would be useful as antidiabetics, 4'-dehydroxyphlorizin derivatives 1a--f were designed, synthesized, and examined for various pharmacological properties related to antidiabetic activity. In normal rats, 1a, e and phlorizin showed a strong SGLT-inhibitory effect and significantly increased urinary glucose on intraperitoneal administration at 10 mg/kg, though only 1a resulted in excretion of large quantities of urinary glucose on oral administration at 100 mg/kg. Compounds 1a, e, and phlorizin markedly inhibited glucose uptake in the small intestine during enteric perfusion in normal rats. Compound 1a had a significant reducing effect on blood glucose in the glucose tolerance test in mice when administered orally and also lowered blood glucose in streptozotocin-induced diabetic rats. The aglycons 2a, e of 1a, e, and 1a showed weak inhibitory effects on the facilitated glucose transporter-1 (GLUT-1) in human erythrocytes, while phloretin had a strong inhibitory effect on GLUT-1. Compound 1a caused no apparent renal damage in rats when administered orally at 1 g/kg for 4 successive weeks. Thus, 1a was considered to be a promising candidate as a lead compound for antidiabetics of a new type, and was selected for further pharmacological evaluation.
Retinal oximeter for the blue-green oximetry technique (2011)

Retinal oximetry offers potential for noninvasive assessment of central venous oxyhemoglobin saturation (SO(2)) via the retinal vessels but requires a calibrated accuracy of ±3% saturation in order to be clinically useful. Prior oximeter designs have been hampered by poor saturation calibration accuracy. We demonstrate that the blue-green oximetry (BGO) technique can provide accuracy within ±3% in swine when multiply scattered light from blood within a retinal vessel is isolated. A noninvasive on-axis scanning retinal oximeter (ROx-3) is constructed that generates a multiwavelength image in the range required for BGO. A field stop in the detection pathway is used in conjunction with an anticonfocal bisecting wire to remove specular vessel reflections and isolate multiply backscattered light from the blood column within a retinal vessel. This design is tested on an enucleated swine eye vessel and a retinal vein in a human volunteer with retinal SO(2) measurements of ∼1 and ∼65%, respectively. These saturations, calculated using the calibration line from earlier work, are internally consistent with a standard error of the mean of ±2% SO(2). The absolute measures are well within the expected saturation range for the site (-1 and 63%). This is the first demonstration of noninvasive on-axis BGO retinal oximetry.
The CMS Auction: Experimental Studies of a Median-Bid Procurement Auction with Nonbinding Bids (2012)

We report on the experimental results of simple auctions with (i) a median-bid pricing rule and (ii) nonbinding bids (winning bids can be withdrawn)—the two central pillars of the competitive bidding program designed by the Centers for Medicare and Medicaid Services (CMS). Comparisons between the performance of the CMS auction and the performance of the excluded-bid auction reveal the problematic nature of the CMS auction. The CMS auction fails to generate competitive prices of goods and fails to satisfy demand. In all proposed efficiency measures, we find the excluded-bid auction significantly outperforms the CMS auction.
Promotion of allergic immune responses by intranasally-administrated nanosilica particles in mice (2011)

With the increase in use of nanomaterials, there is growing concern regarding their potential health risks. However, few studies have assessed the role of the different physical characteristics of nanomaterials in allergic responses. Here, we examined whether intranasally administered silica particles of various sizes have the capacity to promote allergic immune responses in mice. We used nanosilica particles with diameters of 30 or 70 nm (nSP30 or nSP70, respectively), and conventional micro-sized silica particles with diameters of 300 or 1000 nm (nSP300 or mSP1000, respectively). Mice were intranasally exposed to ovalbumin (OVA) plus each silica particle, and the levels of OVA-specific antibodies (Abs) in the plasma were determined. Intranasal exposure to OVA plus smaller nanosilica particles tended to induce a higher level of OVA-specific immunoglobulin (Ig) E, IgG and IgG1 Abs than did exposure to OVA plus larger silica particles. Splenocytes from mice exposed to OVA plus nSP30 secreted higher levels of Th2-type cytokines than mice exposed to OVA alone. Taken together, these results indicate that nanosilica particles can induce allergen-specific Th2-type allergic immune responses in vivo. This study provides the foundations for the establishment of safe and effective forms of nanosilica particles.
Predicting Downhole Fluid Analysis Logs to Investigate Reservoir Connectivity (2007)

Compartmentalization is perhaps the single biggest risk factor&lt;br&gt;in deepwater petroleum production. Downhole fluid analysis&lt;br&gt;(DFA) is a new tool to reduce uncertainty associated with&lt;br&gt;reservoir connectivity. Fluid data from DFA logs and various&lt;br&gt;laboratory analyses are studied to elucidate hydrocarbon&lt;br&gt;composition variations in large reservoir sand bodies.
Giant Spin Accumulation in Silicon Nonlocal Spin-Transport Devices (2017)

Although electrical injection, transport, and detection of spins in silicon have all been achieved, the induced spin accumulation has been much smaller than expected and desired. Using nonlocal spin-transport devices with an $n$-type Si channel and Fe/MgO magnetic tunnel contacts, the authors demonstrate that it is possible to create a giant spin accumulation in Si, with the spin splitting reaching 13 meV. This result enables the development of Si spintronic devices with a large magnetic response.
Resolving occlusion in multiframe reconstruction of deformable surfaces (2011)

Occlusion is troublesome for almost all computer vision algorithms. To a certain extent, the difficulty is alleviated when multiple frames are given. On the other hand, when we consider the recovery of shapes of moving deformable objects, observed using a monocular camera, the problem appears difficult again. In this paper, we show a method that outperforms previous approaches to reconstruction when feature data is unavailable, perhaps due to occlusion. Our key intuition is that portions of the surface that are visible in some frame can be reliably reconstructed in that frame; further, the reliable portions can be stitched together to find even missing portions, much the way a human eye would hallucinate. Our techniques are based on optimization in Riemannian shape spaces, and is demonstrated on isometric surfaces without involving any kind of machine learning methods.
Tight Tolerance Thermoforming (2001)

Abstract Tighter tolerances are becoming more prevalent as thermoforming applications are increasingly utilized in multiple component assemblies with load bearing and other functional capabilities. A 1 analytical method is described for shrinkage predictions utilizing a thermoviscoelastic constitutive model to try and avoid costly and time consuming forming trials by determine adequacy of the mold and process a-priori. Validation experiments and sensitivity analyses were performed to understand the process behavior and estimate the accuracy of the shrinkage analysis. Design and manufacturing guidelines were then developed to facilitate tight tolerance thermoforming. While the analysis was generally capable of predicting linear shrinkage, statistical yield models indicated that improved process control and further process development is required to consistently produce thermoformed parts to tight tolerances.
Application of Numerical Transient Fluid Dynamics to Snow Avalanche Flow. Part II. Avalanche Modeling and Parameter Error Evaluation (1979)

Abstract Under evaluation is the range of the parameters of internal viscosity and surface friction of flowing avalanches in order to represent the flow numerically by computer program AVALNCH. Nominal values of these parameters are determined to be in the range 0.4 to 0.6 for, snow flowing on snow, with values as high as 0.8 to 0.9 for snow flowing on rough ground. Using a nominal avalanche path, the basic parameters: (1) depth of initial release slab, (2) viscosity and friction, (3) adverse grade, and (4) flow spreading are determined to be in the order listed as regards their relative effect on avalanche runout distance. Program AVALNCH, which permits treatment of flow parameters separately from geometric parameters, provides a versatile tool for the prediction of avalanche runout, as well as for related studies of avalanche dynamics.
High sensitivity biosensor for Staphylococcus Aureus detection based on tapered a singlemode-no core-singlemode fiber structure (2019)

A fiber biosensor based on tapered singlemode-no core-singlemode (SNS) fiber structure was investigated for the detection of staphylococcus aureus. The fibre sensor was functionalised by depositing the pig IgG antibodies onto tapered biosensor surface, which has specific binding with staphylococcus aureus. The experimental results showed that transmission spectrum of functionalized sensor undergone wavelength blue shift when it was immersed into Staphylococcus aureus solution, and 1.1 nm wavelength shift was observed with a concentration of 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup> colony-forming units (CFU)/mL.
A novel technique to reduce the metastability of Bang-Bang Phase Frequency Detectors (2011)

This paper presents a new architecture of bang- bang phase frequency detector based on standard cells. The pro- posed architecture presents advantages in terms of compatibility with fully-automated design flow of digital circuitry compared with other architectures. The metastability failure is also studied. The reliability of this architecture is approved by simulation results in CMOS65 nm.
Radar signal pre-processing to suppress surface bounce and multipath (2023)

A method and system for detecting the presence of subsurface objects within a medium is provided. In some embodiments, the imaging and detection system operates in a multistatic mode to collect radar return signals generated by an array of transceiver antenna pairs that is positioned across the surface and that travels down the surface. The imaging and detection system pre-processes that return signal to suppress certain undesirable effects. The imaging and detection system then generates synthetic aperture radar images from real aperture radar images generated from the pre-processed return signal. The imaging and detection system then post-processes the synthetic aperture radar images to improve detection of subsurface objects. The imaging and detection system identifies peaks in the energy levels of the post-processed image frame, which indicates the presence of a subsurface object.
O-(2-[F-18]fluoroethyl)-L-tyrosine uptake and blood-brain barrier permeability under anti-angiogenic therapy in rat glioma models (2016)

350 Objectives Positron emission tomography (PET) with O-(2-[F-18]fluoroethyl) -L- tyrosine (FET) is used for therapy monitoring of brain tumors. Under anti-angiogenic therapy with bevacizumab, MRI often shows a reduction of contrast enhancement despite tumor progression (so-called pseudo-regression). This study examines the tumoral FET uptake under anti-angiogenic therapy in relation to the permeability of the blood-brain barrier (BBB). Methods Human U87 glioma cells were implanted into the striatum of 25 immunodeficient RNU rats. After 13-14 days of tumor growth, a dynamic FET PET (60 min) was performed followed by preparation of brains. Group 1 (n=9) received a short-term therapy with 45 mg/kg i.v. bevacizumab 48 h prior to PET scan. Group 2 (n=10) received a long-term therapy with 10 mg/kg i.v. bevacizumab 9 days and 48 hours before FET PET. The BBB permeability was histologically determined based on the extravasation of Evans Blue (2% Evans Blue i.v. 30 min before sacrifice). As a control group, FET PET scans of the short-term group before start of the treatment (n=7) were evaluated as well as Evans Blue extravasation of 6 untreated animals. The FET uptake was measured by volume of-interest (VOI) analysis (kinetics, SUV, tumor/brain ratio). Results The BBB permeability slightly decreased under bevacizumab therapy in the short-term group, while the decrease was significant in the long-term group compared to the control group (P=0.014). The FET accumulation kinetics in all three groups showed a plateau-like form and were congruent after 20 min p.i.. Under bevacizumab therapy, tumor SUV and tumor/brain ratio showed no significant differences compared to the control Group. Conclusions Under anti-angiogenic therapy with bevacizumab, the observed changes in BBB permeability showed no significant impact on the FET uptake of brain tumors. These studies confirm that the FET PET is superior to MRI during treatment monitoring of brain tumors under anti-angiogenic therapy.
Linear Bandit Algorithms with Sublinear Time Complexity (2021)

We propose two linear bandits algorithms with per-step complexity sublinear in the number of arms $K$. The algorithms are designed for applications where the arm set is extremely large and slowly changing. Our key realization is that choosing an arm reduces to a maximum inner product search (MIPS) problem, which can be solved approximately without breaking regret guarantees. Existing approximate MIPS solvers run in sublinear time. We extend those solvers and present theoretical guarantees for online learning problems, where adaptivity (i.e., a later step depends on the feedback in previous steps) becomes a unique challenge. We then explicitly characterize the tradeoff between the per-step complexity and regret. For sufficiently large $K$, our algorithms have sublinear per-step complexity and $\tilde O(\sqrt{T})$ regret. Empirically, we evaluate our proposed algorithms in a synthetic environment and a real-world online movie recommendation problem. Our proposed algorithms can deliver a more than 72 times speedup compared to the linear time baselines while retaining similar regret.
Delineating the genotypic and phenotypic spectrum of HECW2-related neurodevelopmental disorders (2021)

We provide a comprehensive review and expansion of the genotypic and phenotypic spectrum of <i>HECW2</i> disorders, aiding future molecular and clinical diagnosis and management.
Probing the leak pathway: Live‐cell imaging of macromolecule passage through epithelia (2022)

Epithelia compartmentalize multicellular organisms and provide interfacing between the inside and outside. Apart from regulating the exchange of solutes, uptake of nutrients, and excretion of waste products, their major function is to prevent uncontrolled access of foreign material to immune-competent compartments. Progress in understanding this barrier function toward larger solutes and its possible defects, as can be seen in a variety of diseases, is largely hampered by a lack of methods to spatiotemporally resolve transepithelial passage of macromolecules. Using different cell culture epithelia, we applied biotinylated dextran tracers carrying an acceptor fluorophore. These bind to cell-adherent avidin carrying donor fluorophore at the basolateral membranes of single-layered epithelial sheets. Confocal fluorescence microscopy was applied to living epithelia in order to image apical-to-basolateral tracer passage as a Förster resonance energy transfer signal of the fluorescent dextran-avidin pair over time. Stimulated macromolecule passage using barrier-perturbing agents proved its effectiveness for the leak imaging method presented herein. Over hours of imaging, spontaneous leaks were rare, occurring transiently on the scale of minutes and for the most part associated with rearranging cell junctions. The discussed approach to leak imaging is expected to promote the understanding of epithelial barriers, particularly, the nature and dynamics of the epithelial cell leak pathway.
Beam combining technologies for direct diode laser systems at the kW power level (2013)

This paper refers to recent developments within TRUMPFs direct diode laser program. We primarily focus on the development of high-efficient, lower-brightness direct diode laser systems which are currently launched into the market of laser metal brazing and welding. In this context, we report on major technical improvements of individual building blocks of such systems and finally give a brief insight into future brightness-scaling of such systems.
A Low Phase Noise Quadrature LC VCO Using Capacitive Common-Source Coupling (2006)

A low phase noise quadrature LC VCO with inherent tail-current shaping is presented. Two identical differential LC VCOs are locked in quadrature with a capacitor connected between their common-source nodes. This capacitor further drives the oscillators into a tail-current shaping mode, which increases their oscillation amplitude and reduces their phase noise. A multi-band 1.9 GHz differential nMOS quadrature LC VCO prototype has been fabricated in a 0.25 mum BiCMOS process. The measured phase noise is -124.4 dBc/Hz at a 1 MHz offset from a 2.07 GHz carrier while the circuit dissipates only 3 mW from a 1.5 V supply. The quadrature VCO is tunable from 1.75 GHz to 2.1 GHz and the VCO core only occupies 0.625mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup>
848: The Increasing Use of Intravesical Therapies for T1 Bladder Cancer Coincides with Decreasing Survival after Cystectomy (2006)

You have accessJournal of UrologyModerated Poster, Monday, May 22, 2006, 1:00 - 3:00 pm1 Apr 2006848: The Increasing Use of Intravesical Therapies for T1 Bladder Cancer Coincides with Decreasing Survival after Cystectomy Erica H. Lambert, Phillip M. Pierorazio, Stephen A. Poon, Aaron E. Katz, Erle T. Goluboff, Cari A. Olsson, Mitchell C. Benson, and James M. McKiernan Erica H. LambertErica H. Lambert , Phillip M. PierorazioPhillip M. Pierorazio , Stephen A. PoonStephen A. Poon , Aaron E. KatzAaron E. Katz , Erle T. GoluboffErle T. Goluboff , Cari A. OlssonCari A. Olsson , Mitchell C. BensonMitchell C. Benson , and James M. McKiernanJames M. McKiernan View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)33084-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "848: The Increasing Use of Intravesical Therapies for T1 Bladder Cancer Coincides with Decreasing Survival after Cystectomy." The Journal of Urology, 175(4S), pp. 273–274 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 273-274 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetrics Author Information Erica H. Lambert More articles by this author Phillip M. Pierorazio More articles by this author Stephen A. Poon More articles by this author Aaron E. Katz More articles by this author Erle T. Goluboff More articles by this author Cari A. Olsson More articles by this author Mitchell C. Benson More articles by this author James M. McKiernan More articles by this author Expand All Advertisement PDF downloadLoading ...
Advanced Turboprop Propulsion System Reliability and Maintenance Cost (1977)

&lt;div class="htmlview paragraph"&gt;The reliability and maintenance cost (R&amp;amp;MC) for an advanced turbine engine and prop-fan propulsion system is projected for high speed commercial airline use in the 1990s. The R&amp;amp;MC values are compared with current turboprop values and detailed discussion of the advances necessary to achieve the projected R&amp;amp;MC is provided to substantiate maintenance cost reductions on the order of 50 to 60%. These advances include an on-condition maintenance philosophy in conjunction with diagnostics to monitor system performance, improved reliability in the initial design that is consistent with airline usage and life requirements, improved modularity to reduce line maintenance time and aircraft down time, and simplified hardware in conjunction with modularity to reduce shop maintenance cost. Comparison of the advanced turboprop system maintenance cost with that of an advanced turbofan system shows it has competitive levels.&lt;/div&gt;
Micro-optical modules fabricated by high-precision replication processes (2002)

Double-sided optical modules are fabricated by precision replication in environmentally resistant polymers and sol-gel materials. Due to their competitive prices they are of remarkable interest for datacom applications. Wafer scale processes and injection molding are addressed.
Modal Amplitude and Phase Estimation of NFP of Six-Mode FMF Based on Artificial Neural Network with the Help of Grey-Wolf-Optimizer (2020)

A simple and efficient method for estimating modal amplitude and phase of few-mode-fiber based on artificial-neural-network with the help of grey-wolf-optimizer is proposed. Experimentally obtained six-mode near-field-patterns of recently proposed six-mode mixer are analyzed and successfully reproduced for the first time.