gebhart/patrepeval huggingface dataset:
Towards an architecture for service-oriented process monitoring and control (2010)

The initiative AESOP (ArchitecturE for Service-Oriented Process-Monitoring and - Control) envisions a Service-oriented Architecture approach for monitoring and control of Process Control applications (batch and continuous process). Large process industry systems are a complex (potentially very large) set of (frequently) multi-disciplinary, connected, heterogeneous systems that function as a complex system of which the components are themselves systems. The future “Perfect Plant” will be able to seamlessly collaborate and enable monitoring and control information flow in a cross-layer way. As such the different systems will be part of an SCADA/DCS ecosystem, where components can be dynamically added or removed and dynamic discovery enables the on-demand information combination and collaboration. All current and future systems will be able to share information in a timely and open manner, enabling an enterprise-wide system of systems that will dynamically evolve based on business needs. The SOA-based approach proposed by AESOP can, on one hand, simplify the integration of monitoring and control systems on application layer. On the other hand, the networking technologies that are already known to control engineers could also simplify the inclusion of or migration from existing solutions and integration of the next generation SCADA and DCS systems at network layer.
Are defect-tolerant circuits with redundancy really cost-effective? Complete and realistic cost model (2002)

Yield enhancement for fault tolerant circuits with redundancy has been widely studied during the last years. Recent manufacturing technologies have brought out steady and significant improvement regarding contamination and defect density and have forced us to re-evaluate the economical advantages of circuits with redundancy. The main goal of this paper is to propose a realistic cost model for fault tolerant chips that includes manufacturing, test and reconfiguration processing steps. We demonstrate, with our model, how optimum and cost-effective redundancy levels can be determined, for a class of fault tolerant architectures, and we compare our results to the usual figure of merit calculation. We demonstrate that wafer test costs can have significant impact on the cost effectiveness of redundant implementation. This model also leads us to show that for a optimized fault tolerant chip, the silicon cost tends to increase as a quasi-linear function of chip area. We finally demonstrate that, considering future fault densities expected for the next decade, economical advantages of redundancy will probably vanish for most integrated circuits when they are implemented with mature processes.
Long- and short-range correlations and their event-scale dependence in high-multiplicity pp collisions at $$ \sqrt{s} $$ = 13 TeV (2021)

A bstract Two-particle angular correlations are measured in high-multiplicity proton-proton collisions at $$ \sqrt{s} $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msqrt><mml:mi>s</mml:mi></mml:msqrt></mml:math> = 13 TeV by the ALICE Collaboration. The yields of particle pairs at short-(∆ η ∼ 0) and long-range (1 . 6 &lt; |∆ η | &lt; 1 . 8) in pseudorapidity are extracted on the near-side (∆ φ ∼ 0). They are reported as a function of transverse momentum ( p T ) in the range 1 &lt; p T &lt; 4 GeV/ c . Furthermore, the event-scale dependence is studied for the first time by requiring the presence of high- p T leading particles or jets for varying p T thresholds. The results demonstrate that the long-range “ridge” yield, possibly related to the collective behavior of the system, is present in events with high- p T processes as well. The magnitudes of the short- and long-range yields are found to grow with the event scale. The results are compared to EPOS LHC and PYTHIA 8 calculations, with and without string-shoving interactions. It is found that while both models describe the qualitative trends in the data, calculations from EPOS LHC show a better quantitative agreement for the p T dependency, while overestimating the event-scale dependency.
Image acquisition and calibration methods in quantitative confocal laser scanning microscopy (1996)

Quantitative measurements in far field light microscopy are complicated by the different lateral and axial resolutions. For principle reasons the spatial resolution in the direction of the optical axis is lower than in the focal plane. To overcome these limitations, we have developed a 2(pi) -tilting device for full specimen rotation perpendicular to the optical axis. Due to the influence of specimen and mounting media on the spatial resolution of a CLSM, the focal shift increases with the refractive index mismatch and the depth of the investigated region. Attenuation and absorption effects of excitation and emitted light due to layer thickness and refractive index mismatches have to be considered. By means of a capillary with a square shaped cavity in combination with the tilting device, it may become possible to directly calibrate the confocal system in the direction of the optical axis. With this technique it is possible to test 3D deconvolution and segmentation procedures applied to the same object acquired under different perspectives.
Design and synthesis of novel phenylaminopyrimidines with antiproliferative activity against colorectal cancer (2019)

A new series of phenylaminopyrimidine (PAP) derivatives was designed and synthesized to act against tyrosine kinases for the treatment of cancer.
Interspecies comparison of prostate cancer gene‐expression profiles reveals genes associated with aggressive tumors (2009)

Prostate cancer (PC) is a heterogeneous disease whose aggressive phenotype is the second leading cause of cancer-related death in men. The identification of key molecules and pathways that play a pivotal role in PC progression towards an aggressive form is crucial. A major effort towards this end has been taken by global analyses of gene expression profiles. However, the large body of data did not provide a definitive idea about the genes which are associated with the aggressive growth of PC. In order to identify such genes, we performed an interspecies comparison between several human data sets and high quality microarray data that we generated from the transgenic adenocarcinoma of mouse prostate (TRAMP) strain. The TRAMP PC mimics the histological and pathological appearance as well as the aggressive phenotype of human PC (huPC). Analysis of the microarray data, derived from microdissected TRAMP specimens removed at different stages of the disease yielded genetic signatures delineating the TRAMP PC development and progression. Comparison of the TRAMP data with a set of genes representing the core expression signature of huPC yielded a limited set genes. Some of these genes are known predictors of poor prognosis in huPC. Interestingly, the modulation of genes responsible for the invasive phenotype of huPC occurs in TRAMP already during the transition to prostate intraepithelial neoplasia (PIN) and onwards to localized tumors. We therefore suggest that critical oncogenic events leading to an aggressive phenotype of huPC can be studied in the PIN stage of TRAMP.
FLUORESCENCE LINE‐NARROWING STUDIES OF ANTIBODY‐BENZO[a]PYRENE TETROL COMPLEXES (1993)

Benzo[a]pyrene tetrol (BPT) was used as a fluorescent probe to investigate the nature of antigen binding by two different monoclonal antibodies (MAb) that recognize a variety of derivatives of anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10- tetrahydrobenzo[a]pyrenes (BPDE). Fluorescence line-narrowed spectra of the physical complexes of BPT formed with antibodies 8E11 and 3C3 were recorded at 4 K by employing vibronic excitation into the S1 electronic state. The frequencies of the vibrational modes of the S1 state were only marginally affected, though changes in relative intensities of some bands were observed. Fluorescence spectra recorded at 77 K by excitation into the S2 state showed that the (0,0) fluorescence emission of BPT was shifted to red on complex formation. Intensity ratios of the (0,0) band and the main vibrational band at 1300 cm-1 were used to assess the degree of interior binding of the chromophore. Quenching studies with acrylamide were employed to designate the complexes as type I, solvent inaccessible, or type II, solvent accessible. These studies also indicated that antibody 3C3 complexes tend to be more heterogeneous compared to the 8E11 complex. Deuterated BPT-d-12 also formed complexes with both antibodies, however, with different quenching behavior.
Molecular aerobiology – <i>Plantago</i> allergen Pla l 1 in the atmosphere (2014)

The presence of Pla l 1 in the atmosphere depends not only on Plantago pollen but also on the pollen of other species from the Oleaceae family. Knowledge of the behaviour of allergen Pla l 1 in the atmosphere can help understand better asthma exacerbations associated with aeroallergens.
ChemInform Abstract: Organocatalytic Asymmetric Mannich Reactions: New Methodology, Catalyst Design, and Synthetic Applications (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
CD 406, nova variedade de algodão do alto rendimento de fibra para as regiões do cerrado do Brasil (2003)

Obtida do programa de melhoramento genético da Coodetec/Cirad, a linha CD98-225 foi lançada comercialmente em 2002/2003 com a denominação de CD406. Esta variedade foi obtida através do esquema de seleção genealógica a partir de um cruzamento entre variedades de fundo genético Australiano e Sul Americano, e testada pela primeira vez em 1997/98 em Palotina-PR, e nas safras 99/00, 00/01 e 01/02 na rede experimental multilocal da Coodetec nos estados do MT, GO e MG. A variedade CD 406 é um material de ciclo mais determinado que a ITA90, de elevado potencial produtivo, exigente em fertilidade e responsiva, com rendimento de fibra muito elevado (40% comercial) e adaptada à colheita mecânica. Sua resistência é voltada à doença azul e bacteriose com relativa tolerância as doenças foliares. A qualidade de sua fibra fica dentro do padrão produzido atualmente no cerrado, muito parecida com a fibra da ITA90. A CD 406 é uma variedade direcionada para os produtores tecnificados das regiões do cerrado.
No effect of TETRA hand portable transmission signals on human cognitive function and symptoms (2010)

Current radio frequency radiation exposure guidelines rest on well-established thermal effects. However, recent research into analogue and digital transmission fields at levels covered by the exposure guidelines has indicated possible detrimental effects on human cognitive performance. To investigate this, we conducted a controlled climate chamber study of possible changes in cognitive performance in healthy volunteers exposed to transmission signals from TETRA hand portables (TETRA handsets). The trial deployed a balanced, randomized, double-blinded cross-over design. Performance on different paper-and-pencil, auditory and computer-based cognitive tasks was monitored in 53 male volunteers (mean age 36.41 years, SD 8.35) during 45-min exposure to a TETRA handset and sham control signals remotely controlled from a laboratory more than 100 km away. The main cognitive outcome was the Trail Making B (TMB) test. In addition, the participants completed a computer-based questionnaire measuring self-reported psychological and physical symptoms. No statistically significant differences (P < 0.05) between the TETRA and sham conditions were found for either TMB (estimated difference 3.8%, confidence interval (CI) -1.6% to 9.2%) or any of the remaining cognitive tasks or symptoms. In conclusion, we found no evidence that brief exposure to hand-held TETRA transmitters' affects human cognitive function or subjective symptoms.
Endoscopic Ultrasound (EUS)-Guided Angiotherapyof Refractory Gastrointestinal Bleeding (2007)

EUS-guided angiotherapy appears safe and effective in managing selected patients with clinically severe or occult GI bleeding from lesions potentially refractory to standard endoscopic and/or angiographic techniques. Further studies are needed to confirm the safety and efficacy and to refine the selection criteria in an effort to improve patient care.
Psychosine, Cytokinesis, and Orphan Receptors (2001)

One of the most exciting aspects of modern cell biology is the potential to make connections between disparate areas of research, and thus open up new lines of enquiry. Two recent papers have done just this ([Kanazawa et al. 2000][1]; [Im et al. 2001][2], this issue). Building on the biochemical
Polarized near-infrared intersubband absorptions in CdSe colloidal quantum wells (2019)

Abstract Colloidal quantum wells are two-dimensional materials grown with atomically-precise thickness that dictates their electronic structure. Although intersubband absorption in epitaxial quantum wells is well-known, analogous observations in non-epitaxial two-dimensional materials are sparse. Here we show that CdSe nanoplatelet quantum wells have narrow (30–200 meV), polarized intersubband absorption features when photoexcited or under applied bias, which can be tuned by thickness across the near-infrared (NIR) spectral window (900–1600 nm) inclusive of important telecommunications wavelengths. By examination of the optical absorption and polarization-resolved measurements, the NIR absorptions are assigned to electron intersubband transitions. Under photoexcitation, the intersubband features display hot carrier and Auger recombination effects similar to excitonic absorptions. Sequenced two-color photoexcitation permits the sub-picosecond modulation of the carrier temperature in such colloidal quantum wells. This work suggests that colloidal quantum wells may be promising building blocks for NIR technologies.
Simulation of the Transient Potential Distribution On-Chip During a Fast ESD Event Based on a Parametric Measurement Analysis (2020)

ESD events on semiconductor devices in the pico-or nanosecond range cause local potential differences and are often responsible for severe damages of an IC. The presented simulation approach focuses on the simulation of the transient and local potential distribution on the chip during a discharge on wafer-level. In the approach, the total charge is distributed either via the top metal layer and also via the underlying substrate layer dependent on the IC design. The approach consists of a network-based simulation with uniform cells of lumped elements, which values are determined based on measurement data.
Physics of laser fusion. Volume IV. The future development of high-power solid-state laser systems (1982)

Solid state lasers, particularly neodymium glass systems, have undergone intensive development during the last decade. In this paper, we review solid state laser technology in the context of high-peak-power systems for inertial confinement fusion. Specifically addressed are five major factors: efficiency, wavelength flexibility, average power, system complexity, and cost; these factors today limit broader application of the technology. We conclude that each of these factors can be greatly improved within current fundamental physical limits. We further conclude that the systematic development of new solid state laser madia, both vitreous and crystalline, should ultimately permit the development of wavelength-flexible, very high average power systems with overall efficiencies in the range of 10 to 20%.
Force/Torque Field Generation to Obtain Local Properties within Soft Hydrogels (2007)

Soft media like hydrogels are used as substrates for cellular engineering of different cell types and the stiffness of these media plays an important role in the cellular behavior like adhesion, proliferation, matrix deposition and differentiation. The global mechanical properties of such substrates were previously calculated using spherical beads embedded in micro-liter samples and then deflecting them by a magnetic manipulator [1]. Knowing the force and the displacement the elastic modulus was evaluated using closed form solutions. However in the context of our studies for biological applications there are circumstances where the local elastic properties of the hydrogel play an important role. For example in the vicinity of a cell, the cell will distort the gel and the modulus of elasticity of the surface may get altered, particularly if the gel is non-linear and if the distortions are substantial. In order to measure these local properties a four magnet manipulator based on Amblard, et al [2] was built, which is capable of applying large forces on micron sized particles embedded in the media.
Differentiable Greedy Networks (2018)

Optimal selection of a subset of items from a given set is a hard problem that requires combinatorial optimization. In this paper, we propose a subset selection algorithm that is trainable with gradient-based methods yet achieves near-optimal performance via submodular optimization. We focus on the task of identifying a relevant set of sentences for claim verification in the context of the FEVER task. Conventional methods for this task look at sentences on their individual merit and thus do not optimize the informativeness of sentences as a set. We show that our proposed method which builds on the idea of unfolding a greedy algorithm into a computational graph allows both interpretability and gradient-based training. The proposed differentiable greedy network (DGN) outperforms discrete optimization algorithms as well as other baseline methods in terms of precision and recall.
Normal-mode analysis of underwater-sound propagation with directional sources and receivers (1974)

Standard normal-mode analysis of underwater-sound propagation assumes only an omnidirectional point source. Other writers have proposed that, for use in calculations, a virtual line-array of discrete point sources, arranged vertically, can well approximate the directivity pattern, in the vertical plane, of actual sources. It seems better, however, to use an equivalent vertical line array with a continuous distribution of strength and phase. The equations for relating the actual source and the line source are given, and their solution is discussed. Identical methods allow the calculation of reception by a directional receiver. A related topic, use of a vertical array of discrete elements to stimulate or receive a single mode, is also discussed. An illustrative directivity pattern is presented, for an array adjusted to select the first mode in a shallow-water problem.
Deletion of KCNJ10 eliminates potassium conductance in the basolateral membrane of the early distal convoluted tubule (DCT1). (893.17) (2014)

The basolateral K channels in the DCT1 are composed of KCNJ10 and KCNJ16. Moreover, a 20 pS K channel was detected in the basolateral membrane of DCT of KCNJ16 knockout mice, suggesting that KCNJ10 alone is able to form homotetramers in the absence of KCNJ16. The aim of the present study is to test whether deletion of KCNJ10 would eliminate the basolateral K channel activity in the DCT1. Global deletion of KCNJ10 significantly impaired the animal growth, and the body weight of KCNJ10‐/‐ mice was significantly lower than that of their +/+ and +/‐ littermates. Moreover, KCNJ10‐/‐ mice did not survive beyond postnatal day 9‐12, while KCNJ10+/‐ mice had a life span similar to that of wt. To study the role of KCNJ10 in constructing the basolateral K channel, we performed patch‐clamp experiments in the isolated DCT1 of 8‐10 days old KCNJ10‐/‐, +/‐ and +/+ mice. The patch‐clamp study detected a 40 pS K channel in the basolateral membrane of the DCT1 of wt and KCNJ10+/‐, but not in KCNJ10 ‐/‐ mice. We also measured the Ba 2+ ‐sensitive whole cell K currents which represent the basolateral K channel activity in the DCT1 since it has no apical K conductance. The mean Ba 2+ ‐sensitive K currents at ‐60 mV were 2950 pA (wt), 1400 pA (+/‐) and 250 pA (‐/‐), respectively. Thus, deletion of KCNJ10 largely eliminated the basolateral K conductance in DCT1. We conclude that KCNJ10 is a major type of K channel expressed in the basolateral membrane of the DCT1. Grant Funding Source : NIH
A CMOS single-chip transceiver design for 700/800/900MHz wireless sensor network applications (2014)

This paper presents a low-power CMOS single-chip transceiver for sub-GHz wireless sensor network applications, which complies IEEE 802.15.4-2012 standard. It embodies RF transceiver section based on direct-conversion transmitter and low-IF receiver architecture. To validate its operation, the prototype is fabricated in 0.18um GF standard CMOS process. It shows +5dBm TX output power and −85dBm RX sensitivity. Furthermore, RX dynamic range reaches up to 90dB. The transceiver consumes 26mA and 18mA for TX and RX operations under 1.8V supply voltage, respectively. It occupies 10mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> active area for the RF transceiver section.
Smart filters for image sensor enhancement (2019)

Remote sensing systems of various kinds are the most widely used tools for acquiring information within all areas of our life. However, those optical sensors, cameras and imaging systems are susceptible to blindness and/or damages due to high power signal entering their optics. This paper presents a family of non-linear, solid-state passive wideband smart protection filters. These filters have advantages over fixed spectral filters, which permanently block only specific wavelengths, in that the wideband filter is transparent at all wavelengths until it is hit by damaging light. At input powers below threshold, the filter has high transmission over the whole spectral band. However, when the input power exceeds the threshold power, transmission is decreased dramatically. We present a novel technology for protection of any imaging system, sensors and the human eye against sun blindness as well as laser threats from the visible and up to the infrared (IR).
MC3T3-E1 Osteoprogenitor Cells Systemically Migrate to a Bone Defect and Enhance Bone Healing (2011)

Although iliac crest autologous bone graft remains the gold standard for treatment of bone defects, delayed- and nonunions, and arthrodeses, several alternative strategies have been attempted, including the use of mesenchymal stem cells. Whether cells from the osteoblast lineage demonstrate systemic recruitment to an acute bone defect or fracture, and whether these cells directly participate in bone healing is controversial. This study tests two hypotheses: (1) that exogenous murine MC3T3-E1 osteoprogenitor cells with a high propensity for osteoblast differentiation are able to systemically migrate to a bone defect and (2) that the migrated MC3T3-E1 cells enhance bone healing. Two groups of nude mice were used; a bone defect was drilled in the left femoral shaft in both groups. MC3T3-E1 were used as reporter cells and injected in the left ventricle of the heart, to avoid sequestration in the lungs. Injection of saline served as a control. We used bioluminescence and microCT to assay cell recruitment and bone mineral density (BMD). Immunohistochemical staining was used to confirm the migration of reporter cells. MC3T3-E1 cells were found to systemically migrate to the bone defect. Further, BMD at the defect was significantly increased when cells were injected. Systemic cell therapy using osteoprogenitor cells may be a potential strategy to enhance bone healing.
A review on ESD protection for RF and microwave ICs (2004)

This paper reviews the key issues in designing on-chip ESD (electrostatic discharge) protection structures for RF and microwave ICs. ESD protection basics, uniqueness in RF ESD protection, design methods, RF ESD protection characterization techniques and design optimization are discussed.