gebhart/patrepeval huggingface dataset:
Users manual for the US baseline corn and soybean segment classification procedure (1981)

A user's manual for the classification component of the FY-81 U.S. Corn and Soybean Pilot Experiment in the Foreign Commodity Production Forecasting Project of AgRISTARS is presented. This experiment is one of several major experiments in AgRISTARS designed to measure and advance the remote sensing technologies for cropland inventory. The classification procedure discussed is designed to produce segment proportion estimates for corn and soybeans in the U.S. Corn Belt (Iowa, Indiana, and Illinois) using LANDSAT data. The estimates are produced by an integrated Analyst/Machine procedure. The Analyst selects acquisitions, participates in stratification, and assigns crop labels to selected samples. In concert with the Analyst, the machine digitally preprocesses LANDSAT data to remove external effects, stratifies the data into field like units and into spectrally similar groups, statistically samples the data for Analyst labeling, and combines the labeled samples into a final estimate.
Maximizing waveguide integration density with multi-plane photonics (2017)

We propose and experimentally demonstrate a photonic routing architecture that can efficiently utilize the space of multi-plane (3D) photonic integration. A wafer with three planes of amorphous silicon waveguides was fabricated and characterized, demonstrating $&lt;3\times10^{-4}$ dB loss per out-of-plane waveguide crossing, $0.05 \pm 0.02 $ dB per interplane coupler, and microring resonators on three planes with a quality factors up to $8.2 \times 10^{4}$. We also explore a phase velocity mapping strategy to mitigate the crosstalk between co-propagating waveguides on different planes. These results expand the utility of 3D photonic integration for applications such as optical interconnects, neuromorphic computing and optical phased arrays.
Engineered Nanomaterials Impact Biological Carbon Conversion in Soils (2014)

Engineered nanomaterials (ENMs) increasingly used in commercial products can accumulate in biosolids. Land application of biosolids potentially leads to consequent exposure of ENMs to soils. This article examines the impact of ENM-amended biosolids on biological carbon dioxide production in soils. ENMs, including nano-silver (Ag), zinc oxide (ZnO), titanium dioxide (TiO2), and cerium oxide (CeO2), were applied to soils with dosages of 1 and 1,000 mg/kg, simulating the normal and high concentration exposure scenarios, respectively. Under dark conditions, 1,000 mg/kg of nano-Ag and ZnO exhibited inhibitory effects on aerobic carbon conversion in both a 28-day basal respiration test and a modified 24-h substrate-induced respiration (SIR) test. At 1 and 1,000 mg/kg levels, nano-TiO2 was found to be inert to carbon conversion in both respiration tests. Nano-CeO2 at 1,000 mg/kg exhibited an increased basal respiration rate (48% higher than in the control soil), but having a minimum inhibitory effect in the SIR test. Single particle-inductively coupled plasma–mass spectrometry was used to determine the presence of nano-sized particles in water extracted from soils after 28 days of respiration test. Soils treated with nano-TiO2, CeO2, and Ag released<1% of nanoparticles into the extracted water, while the majority of ENMs were still retained in the soil. Nano- and micron-sized particles containing zinc were not detected even in soils treated with 1,000 mg/kg of nano-ZnO. The findings of this article will inform scientific and regulatory communities about the potential effects of ENMs on microbial respiration in biosolid-amended soils.
Diagnostic accuracy of the D-dimer in children (2017)

D-dimer is currently ordered in children for suspected PE in the emergency care setting, mostly in teenagers. The observed lower limit 95% CIs of 89% and 54% for diagnostic sensitivity and the specificity, respectively, suggest if used in patients with low-clinical probability, a normal D-dimer can safely exclude PE in children.
Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling (2007)

We demonstrate that VEGF isoform-related spatiotemporal cardiac alterations in the VEGF/Notch/ephrinB2 cascade lead to disturbed coronary development. This knowledge can contribute to optimizing therapies targeting VEGF signalling by enabling balancing between angiogenesis and vascular maturation.
Scintillation resistant wavefront sensing based on multi-aperture phase reconstruction technique (2012)

A scintillation resistant sensor that allows retrieval of an input optical wave phase using a multi-aperture phase reconstruction (MAPR) technique is introduced and analyzed. The MAPR sensor is based on a low-resolution lenslet array in the classical Shack-Hartmann arrangement and two high-resolution photo-arrays for simultaneous measurements of pupil- and focal-plane intensity distributions, which are used for retrieval of the wavefront phase in a two stage process: (a) phase reconstruction inside the sensor pupil subregions corresponding to lenslet subapertures and (b) recovery of subaperture averaged phase components (piston phases). Numerical simulations demonstrate the efficiency of the MAPR technique in conditions of strong intensity scintillations and the presence of wavefront branch points.
Validation of the finite-difference time-domain method for near-field bioelectromagnetic simulations (1997)

Validations of the accuracy of the FDTD method for near-field simulations are critical at this time to assess the accuracy of the FDTD method for the simulation of personal communication devices. Excellent comparisons between the FDTD method and analytical or measured results are shown for a dipole antenna next to a layered half-space, a layered box, and a sphere, and also an infinitesimal dipole near a sphere. © 1997 John Wiley & Sons, Inc. Microwave Opt Technol Lett 16: 341–345, 1997.
Amplify or improve detection. (1990)

Quantification with accuracy at the molecular level, by simple means, is the challenge for new generations of biospecific assays. In order to reach this goal, it is necessary to reduce the non-specific background of the current assays and further to amplify the detection signal or to expand the surface of the solid phase. For now, significant additions in performance can be achieved if we balance new ways of amplification with progressive improvements of existing procedures. For the future, new concepts derived form biosensors approach will lead to simultaneous multiple analysis on the same sample.
Implantable Waveguides for Deep-Tissue Photoactivation (2017)

We demonstrated biopolymer waveguides that are gradually resorbed by the tissue and used them for wound closure. The waveguides enabled a 10-fold extension of the photoactivated tissue area in comparision with conventional photochemical bonding.
In vitro pharmacological characterization of the potent, lung selective pan-JAK inhibitor TD-8236 (2019)

Clinical studies with biologics have demonstrated the importance of cytokines in the pathobiology of asthma. However, redundancy and heterogeneity in the asthma cytokine networks may limit the efficacy of single cytokine-targeting biologics. Thus, we set out to discover an inhaled small molecule inhibitor of JAK enzymes, which are critical for the signaling of multiple cytokines. TD-8236 demonstrated pan-JAK inhibitory activity (pKi values 9.8-10.8 at the four JAK kinases) and inhibited IL-13-induced STAT6 phosphorylation (pIC50=8.3) and IL-13 and TNFα-induced CCL26 release (pIC50=8.2) in the bronchial epithelial cell line BEAS-2B. In human primary immune and bronchial epithelial cells, STAT-phosphorylation was potently inhibited downstream of IL-13 (JAK1/2), IL-6 (JAK1/2), IL-4 (JAK1/3), IFNγ (JAK1/2) and IL-12 (JAK2/Tyk2) (pIC50 range 6.6-8.1). TD-8236 also inhibited mediator release downstream of TSLP (CCL17; pIC50=7.1) or IL-2 plus αCD3 (IFNγ; pIC50=7.3). In assays that integrate key features of asthma pathobiology, TD-8236 inhibited IL-5-induced eosinophil survival at IL-5 concentrations relevant to levels observed in eosinophilic asthma (pIC50=6.5) whereas the steroid fluticasone propionate (FP) had no effect (pIC50&gt;5). In 3D bronchial epithelial cell cultures derived from asthma patients, spontaneous periostin and IL-6 release was inhibited by TD-8236 to a greater extent than by FP (% max inh. 92±5 vs. 60±26). Collectively, these data show that TD-8236 is a potent pan-JAK inhibitor that blocks multiple asthma-relevant cytokine pathways <i>in vitro</i>. This profile supports further development of TD-8236 as a novel inhaled non-steroidal therapy to address the needs of asthma patients.
Organic Solute Transporter Alpha Deficiency: A Disorder With Cholestasis, Liver Fibrosis, and Congenital Diarrhea (2019)

Gao, Emily; Cheema, Huma; Waheed, Nadia; Mushtaq, Iqra; Erden, Nihan; Nelson‐Williams, Carol; Jain, Dhanpat; Soroka, Carol J.; Boyer, James L.; Khalil, Youssef; Clayton, Peter T.; Mistry, Pramod K.; Lifton, Richard P.; Vilarinho, Sílvia Author Information
Carotid Artery Plaque Components Classification Using Homodyned-K Parametric Maps and Elastograms (2018)

Multiple quantitative ultrasound (QUS) features are available from a single ultrasound radiofrequency (RF) acquisition. The objective was to test if the combination of homodyned-K (HK), elastogram, and echogenicity features could improve carotid artery plaque components characterization compared to these same features taken separately.
Microlayer and nanolayer tubing and piping via layer multiplication coextrusion. I. Validation (2019)

ABSTRACT Layered annular structures produced with layer multiplication coextrusion, utilizing both a standard in‐line “spider” die, and a custom annular die, are compared in structures up to 129 layers. One multilayered system, of a Dow LDPE 5004I was utilized in generating experimental results to validate the custom die design performance. It was found that the custom design demonstrates successful extrusion of high layer number annular structures with substantial benefits over the standard spider die. Moreover, a design method incorporating angular rotation was implemented within the custom die to eliminate weld lines and attain concentric layer structures to further enhance commercial viability and mechanical integrity. Results indicate angular rotation may be utilized to generate idealized annular products with concentric layer structures. Additionally, exploration of flow through the annular die land was conducted with ANSYS Polyflow in under several conditions of angular rotation. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 137 , 48683.
New Insights into the Retarding Effect of Aluminates on C3S Hydration (2017)

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Chromosome-Specific Staining To Detect Genetic Rearrangements Associated With Chromosome 3 And/Or Chromosone 17 (2023)

Methods and compositions for staining based upon nucleic acid sequence that employ nucleic acid probes are provided. Said methods produce staining patterns that can be tailored for specific cytogenetic analyses. Said probes are appropriate for in situ hybridization and stain both interphase and metaphase chromosomal material with reliable signals. The nucleic acid probes are typically of a complexity greater than 50 kb, the complexity depending upon the cytogenetic application. Methods and reagents are provided for the detection of genetic rearrangements. Probes and test kits are provided for use in detecting genetic rearrangements, particularly for use in tumor cytogenetics, in the detection of disease related loci, specifically cancer, such as chronic myelogenous leukemia (CML), retinoblastoma, ovarian and uterine cancers, and for biological dosimetry. Methods and reagents are described for cytogenetic research, for the differentiation of cytogenetically similar but genetically different diseases, and for many prognostic and diagnostic applications.
Interpreting indigenous art in university collections (2012)

Debates on the representation of indigenous cultures in museums have come to the fore in the past thirty years. This paper examines the context for the opening of Waipapa Marae at the University of Auckland in 1988. It outlines a history of Māori meeting houses used for teaching and learning in a specifically Māori context in the New Zealand tertiary sector. The challenge for the university curator with a marae as part of the collection is how to interpret it for the 21st century. Facilitating a student-led process can make present those who have been traditionally absent in ethnographic exhibitions – the culture group who produced the objects.
Ring‐Closing Olefin Metathesis for the Synthesis of Benzene Derivatives (2006)

Benzene derivatives were synthesized in excellent yield from 1,4,7-trien-3-ols by tandem ruthenium-catalyzed ring-closing olefin metathesis (RCM)/dehydration. The method was extended to the tandem RCM/oxidation process to obtain phenol and aniline derivatives. This method displays many advantages over aromatic-substitution-based classical routes.
Technetium-99m Sestamibi Scintigraphy and Helical CT Together in Patients With Primary Hyperparathyroidism: A Prospective Clinical Study (2004)

No AccessJournal of UrologyUrological Survey: Abstracts: Urolithiasis, Endourology and Laparoscopy1 Nov 2004Technetium-99m Sestamibi Scintigraphy and Helical CT Together in Patients With Primary Hyperparathyroidism: A Prospective Clinical Study Ralph V. ClaymanM.D. Ralph V. ClaymanRalph V. Clayman More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)60971-8AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Technetium-99m Sestamibi Scintigraphy and Helical CT Together in Patients With Primary Hyperparathyroidism: A Prospective Clinical Study." The Journal of Urology, 172(5), p. 2103 © 2004 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 172Issue 5November 2004Page: 2103 Advertisement Copyright & Permissions© 2004 by American Urological Association, Inc.MetricsAuthor Information Ralph V. Clayman More articles by this author Expand All Advertisement PDF downloadLoading ...
Nonmyelin-Specific T Cells Accelerate Development of Central Nervous System APC and Increase Susceptibility to Experimental Autoimmune Encephalomyelitis (2003)

Previously we demonstrated that both myelin-specific and nonmyelin-specific rat T cells were capable of accelerating the development of transplanted rat BM-derived APC in the CNS of SCID C.B-17/scid (SCID) mice. This suggested that nonmyelin-specific T cells might be capable of increasing susceptibility to EAE by increasing the number and function of APC in the CNS before disease induction. To assess this possibility, we evaluated disease incidence, day of onset, duration, mean peak severity, cumulative disease index, and histopathology in the presence or absence of nonmyelin-specific T cells. The results demonstrate an association between T cell responses to nonmyelin Ags, accelerated development of BM-derived CNS APC before disease induction, and heightened susceptibility to CNS inflammation mediated by myelin-specific T cells. This suggests that T cell responses to nonmyelin Ags can potentiate CNS inflammation by elevating the functional presence of CNS APC.
The D614G mutation in Spike: increased infectivity and neutralizing Ab sensitivity and the underlying mechanism [Slides] (2020)

Evidence is presented that there are now more SARS-CoV-2 viruses circulating in the human population globally that have the G614 form that was originally identified from the first human cases in Wuhan, China. Follow-up studies show that patients infected with G614 shed more viral nucleic avid compared with those with D614 and G614-bearing viruses show significantly higher infectious titers in vitro than their D614 counterparts.
Supplementary Figure 1 from A Targeted RNAi Screen of the Breast Cancer Genome Identifies <i>KIF14</i> and <i>TLN1</i> as Genes That Modulate Docetaxel Chemosensitivity in Triple-Negative Breast Cancer (2023)

&lt;p&gt;PDF File - 2103K, Normalization of expression array datasets. Five expression arrays were normalized and pooled (see Methods).&lt;/p&gt;
Cowboys, ankle sprains, and keepers of quality: how is video game development different from software development? (2014)

Video games make up an important part of the software industry, yet the software engineering community rarely studies video games. This imbalance is a problem if video game development differs from general software development, as some game experts suggest. In this paper we describe a study with 14 interviewees and 364 survey respondents. The study elicited substantial differences between video game development and other software development. For example, in game development, “cowboy coders” are necessary to cope with the continuous interplay between creative desires and technical constraints. Consequently, game developers are hesitant to use automated testing because of these tests’ rapid obsolescence in the face of shifting creative desires of game designers. These differences between game and non-game development have implications for research, industry, and practice. For instance, as a starting point for impacting game development, researchers could create testing tools that enable game developers to create tests that assert flexible behavior with little up-front investment.
Combining cathodic protection and antifouling into a single hull system (2013)

The approach presented here demonstrates an energized system that provides cathodic protection and biofouling control that could eliminate anti-fouling hull coatings. Results from immersion panel testing of a variety of electrocatalyst materials and a small-scale Jon boat prototype – as well as experimental measurements of the electrocatalyst material efficiencies and models of oxidant concentrations – were used to design a 1/8-scale prototype installed on a 64 foot Navy research vessel based out of Panama City, Florida. The prototype design was carried out through computational modeling to solve a system of partial differential equations describing the coupling of electric current conservation and mass and electric species transport. The prototype underwent exposure testing for eight months. Regular diver surveys and system data collection monitored the system's effectiveness at maintaining the hull potential and keeping the hull free of biofouling.
Client Defined Private Networks laid over Thin CPEs (2016)

This document specifies a type of private networks that interconnect
thin CPEs at multiple client sites by IP tunnels, or more
specifically, lay over multiple client sites' Thin CPEs via IP
tunnels. Those private overlay networks not only interconnect those
sites by secure IP tunnels but can also enforce the client specified
policies to govern how applications or hosts within those sites
communicate and how to access public internet. Hosts or applications
in those sites can be interconnected by Layer 2 networks or/and by
Layer 3 networks. The network that the IP tunnels are traversing can
be IPv4 or IPv6 networks. This document describes the special
properties of the client defined networks over Thin CPEs. A separate
draft will describes the special features that those IP tunnels need
to have in order to interconnect multiple sites as if those sites are
directly connected by wires and how communication policies are
enforced.
Corrigendum: Trap Inlaid Cationic Hybrid Composite Material for Efficient Segregation of Toxic Chemicals from Water (2022)

In this Research Article, the name of one author (Yogeshwer D. More) was spelled incorrectly. The correct spelling of the name of the author should read as follows: Yogeshwar D. More In addition, a footnote including a statement for equal contribution of two authors was missing. The correct author line and affiliations should read as follows: Sahel Fajal,[a] Writakshi Mandal,[a] Samraj Mollick,[a,+] Yogeshwar D. More,[a,+] Arun Torris,[b] Satyam Saurabh,[a] Mandar M. Shirolkar,[c] and Sujit K. Ghosh*[a] [a] Department of Chemistry, and Centre for Water Research, Indian Institute of Science Education and Research, Dr. Homi Bhabha Road, Pashan, Pune 411008 (India) [b] Polymer Science and Engineering Division, CSIR-National Chemical Laboratory Dr. Homi Bhabha Road, Pune 411008 (India) [c] Symbiosis Center for Nanoscience and Nanotechnology (SCNN), Symbiosis International (Deemed University) (SIU), Lavale, Pune 412115 (India) [+] These authors contributed equally to this work.
Highly heterogeneous epitaxy of flexoelectric BaTiO3-δ membrane on Ge (2022)

The integration of complex oxides with a wide spectrum of functionalities on Si, Ge and flexible substrates is highly demanded for functional devices in information technology. We demonstrate the remote epitaxy of BaTiO<sub>3</sub> (BTO) on Ge using a graphene intermediate layer, which forms a prototype of highly heterogeneous epitaxial systems. The Ge surface orientation dictates the outcome of remote epitaxy. Single crystalline epitaxial BTO<sub>3-δ</sub> films were grown on graphene/Ge (011), whereas graphene/Ge (001) led to textured films. The graphene plays an important role in surface passivation. The remote epitaxial deposition of BTO<sub>3-δ</sub> follows the Volmer-Weber growth mode, with the strain being partially relaxed at the very beginning of the growth. Such BTO<sub>3-δ</sub> films can be easily exfoliated and transferred to arbitrary substrates like Si and flexible polyimide. The transferred BTO<sub>3-δ</sub> films possess enhanced flexoelectric properties with a gauge factor of as high as 1127. These results not only expand the understanding of heteroepitaxy, but also open a pathway for the applications of devices based on complex oxides.