gebhart/patrepeval huggingface dataset:
A generalized program for extracting the control characteristics of resonant converters via the state-plane diagram (1998)

This paper presents a generalized computer program that can be used to derive the control characteristics of resonant power converters from their state-plane trajectories. It has been shown that the geometrical properties of the state-plane trajectory can be used to derive the control characteristics of a given resonant power converter topology. These characteristics are essential in determining the design parameters such as power converter gain, component stresses and required feedback controllers. The main program consists of several subroutines, each of which is associated with a segment of the state-plane trajectory. Such a program will make it faster and easier for a design engineer to obtain the design parameters of any given resonant topology.
3-D Visualization of Flow in Microscale Jet Impingement System (2009)

This paper presents our recent work on the reconstruction of three-dimensional (3-D) flow fields in a microscale jet impingement cooling flows. We use micron-resolution PIV to capture successive two-dimensional (2-D) “slices” of the flow field in a 3-D structure, and compare with models of flow near microscale jets. This approach is specifically constructed to determine the z-component of the flow velocities, which play a key role in enhancing heat transfer at the impingement surface. These new results will enable a predictive design capability for microjet impingement cooling structures for high power electronics.
Adenosine A2B Receptor Deficiency Promotes Host Defenses against Gram-Negative Bacterial Pneumonia (2012)

These data suggest that the absence of A(2B)R signaling enhances antimicrobial activity in gram-negative bacterial pneumonia.
Scheduling hardware/software systems using symbolic techniques (1999)

In this paper, a scheduling method for heterogeneous embedded systems is developed. At first, an internal representation model called FunSrate is presented which enables the explicit representation of nondeterminism and scheduling using a combination of functions and state machines. The new scheduling method is able to deal with mixed data/control Row specifications and takes into account different mechanisms of non-determinism as occurring in the design of embedded systems. Constraints imposed by other already implemented components are respected. Tbe scheduling approach avoids the explicit ennmeration of execution paths by using symbolic techniques and gnarantees to find a deadlock-free and bounded schedule if one exists. The generated schedule consists of statically scheduled basic blocks which are dynamically called at run time.
Guest Editorial: Large-Scale Multiple Antenna Wireless Systems (2013)

The papers in this special issue focus on large-scale multiple antenna wireless systems and services.
Stenotrophomonas-Like Bacteria Are Widespread Symbionts in Cone Snail Venom Ducts (2017)

Cone snails are biomedically important sources of peptide drugs, but it is not known whether snail-associated bacteria affect venom chemistry. To begin to answer this question, we performed 16S rRNA gene amplicon sequencing of eight cone snail species, comparing their microbiomes with each other and with those from a variety of other marine invertebrates. We show that the cone snail microbiome is distinct from those in other marine invertebrates and conserved in specimens from around the world, including the Philippines, Guam, California, and Florida. We found that all venom ducts examined contain diverse 16S rRNA gene sequences bearing closest similarity to <i>Stenotrophomonas</i> bacteria. These sequences represent specific symbionts that live in the lumen of the venom duct, where bioactive venom peptides are synthesized.<b>IMPORTANCE</b> In animals, symbiotic bacteria contribute critically to metabolism. Cone snails are renowned for the production of venoms that are used as medicines and as probes for biological study. In principle, symbiotic bacterial metabolism could either degrade or synthesize active venom components, and previous publications show that bacteria do indeed contribute small molecules to some venoms. Therefore, understanding symbiosis in cone snails will contribute to further drug discovery efforts. Here, we describe an unexpected, specific symbiosis between bacteria and cone snails from around the world.
A Novel Edge-Cloud Interworking Framework in the Video Analytics of the Internet of Things (2019)

This letter proposes a novel edge-cloud interworking framework in the video analytics of the Internet of Things (IoT) that consists of cost-effective job load balancing and scheduling schemes for computation-intensive video analytics applications. The proposed framework aims to minimize the cost of cloud resource usage while guaranteeing deadlines when conducting concurrent operations. A formulation of a two-stage mixed-integer problem and its heuristic greedy algorithms is presented, which captures all intertwined goals. From the numerical analysis, we reveal that the proposed framework outperforms the existing schemes in terms of monetary cost and service latency with a practical complexity bound.
Real-time image deconvolution on the GPU (2010)

Two-dimensional image deconvolution is an important and well-studied problem with applications to image deblurring and restoration. Most of the best deconvolution algorithms use natural image statistics that act as priors to regularize the problem. Recently, Krishnan and Fergus provide a fast deconvolution algorithm that yields results comparable to the current state of the art. They use a hyper-Laplacian image prior to regularize the problem. The resulting optimization problem is solved using alternating minimization in conjunction with a half-quadratic penalty function. In this paper, we provide an efficient CUDA implementation of their algorithm on the GPU. Our implementation leverages many wellknown CUDA optimization techniques, as well as several others that have a significant impact on this particular algorithm. We discuss each of these, as well as make a few observations regarding the CUFFT library. Our experiments were run on an Nvidia GeForce GTX 260. For a single channel image of size 710 x 470, we obtain over 40 fps, while on a larger image of size 1900 x 1266, we get almost 6 fps (without counting disk I/O). In addition to linear performance, we believe ours is the first implementation to perform deconvolutions at video rates. Our running times also demonstrate that our GPU implementation is over 27 times faster than the original CPU implementation.
Intensive care order writing practices in the USA (1991)

HALPERN, NEIL A. MD, FACP; COLUCCI, ROBERT D. PHARMD; ALICEA, MARGARITA RN; GREENSTEIN, ROBERT MD, FACS Author Information
Electrical Conductivity of a 3Y-TZP/Alumina Laminate Composite Synthesized by Electrophoretic Deposition. (2002)

Electrical conductivity measurements were applied to a 3Y-TZP/alumina laminate composite fabricated by electrophoretic deposition in order to evaluate characteristics of its laminar structure non-destructively. Electrical conductivity of the composite was measured in directions parallel and perpendicular to the alumina layers. The composite showed the electrical properties of 3Y-TZP in the direction parallel to the alumina layers, and those of alumina in the perpendicular direction. Electrical conductivity measurements well reflected the laminar structure of the zirconia/alumina composite.
Alternatives for Multilevel Transparent Interconnection of Lots of Links (TRILL) (2017)

Although TRILL is based on IS-IS, which supports multilevel unicast
routing, extending TRILL to multiple levels has challenges that are
not addressed by the already-existing capabilities of IS-IS. One issue
is with the handling of multi-destination packet distribution trees.
Other issues are with TRILL switch nicknames. How are such nicknames
allocated across a multilevel TRILL network? Do nicknames need to be
unique across an entire multilevel TRILL network? Or can they merely
be unique within each multilevel area? This informational document
enumerates and examines alternatives based on a number of factors
including backward compatibility, simplicity, and scalability; it
makes recommendations in some cases.
Review of Nucleic Acid Amplification Tests and Clinical Prediction Rules for Diagnosis of Tuberculosis in Acute Care Facilities (2015)

Tuberculosis (TB) remains an important cause of hospitalization and mortality in the United States. Prevention of TB transmission in acute care facilities relies on prompt identification and implementation of airborne isolation, rapid diagnosis, and treatment of presumptive pulmonary TB patients. In areas with low TB burden, this strategy may result in inefficient utilization of airborne infection isolation rooms (AIIRs). We reviewed TB epidemiology and diagnostic approaches to inform optimal TB detection in low-burden settings. Published clinical prediction rules for individual studies have a sensitivity ranging from 81% to 100% and specificity ranging from 14% to 63% for detection of culture-positive pulmonary TB patients admitted to acute care facilities. Nucleic acid amplification tests (NAATs) have a specificity of >98%, and the sensitivity of NAATs varies by acid-fast bacilli sputum smear status (positive smear, ≥95%; negative smear, 50%-70%). We propose an infection prevention strategy using a clinical prediction rule to identify patients who warrant diagnostic evaluation for TB in an AIIR with an NAAT. Future studies are needed to evaluate whether use of clinical prediction rules and NAATs results in optimized utilization of AIIRs and improved detection and treatment of presumptive pulmonary TB patients.
Transcriptional Regulatory Networks in Hepatitis C Virus-induced Hepatocellular Carcinoma (2018)

Understanding the transcriptional regulatory elements that influence the progression of liver disease in the presence of hepatitis C virus (HCV) infection is critical for the development of diagnostic and therapeutic approaches. Systems biology provides a roadmap by which these elements may be integrated. In this study, a previously published dataset of 124 microarray samples was analyzed in order to determine differentially expressed genes across four tissue types/conditions (normal, cirrhosis, cirrhosis HCC, and HCC). Differentially expressed genes were assessed for their functional clustering and those genes were annotated with their potential transcription factors and miRNAs. Transcriptional regulatory networks were constructed for each pairwise comparison between the 4 tissue types/conditions. Based on our analysis, it is predicted that the disruption in the regulation of transcription factors such as AP-1, PPARγ, and NF-κB could contribute to the liver progression from cirrhosis to steatosis and eventually to HCC. Whereas the condition of the liver digresses, the downregulation of miRNAs' (such as miR-27, Let-7, and miR-106a) expression makes the transition of the liver through each pathological stage more apparent. This preliminary data can be used to guide future experimental work. An understanding of the transcriptional regulatory attributes acts as a road map to help design interference strategies in order to target the key regulators of progression of HCV induced HCC.
Up-regulation of steroid sulphatase activity in HL60 promyelocytic cells by retinoids and 1α,25-dihydroxyvitamin D3 (2001)

HL60 promyeloid cells express both classes of oestrogen receptor (ERα and ERβ). We show that hydrolysis of oestrone sulphate by steroid sulphatase is a major source of oestrone in HL60 cells, and that most of the released oestrone is not metabolized further to 17β-oestradiol. Treatment of HL60 cells with retinoids or 1α,25-dihydroxyvitamin D3 increased steroid sulphatase mRNA and activity in parallel with the induction of CD11b, an early marker of myeloid differentiation that is expressed before the differentiating cells stop proliferating. Use of agonists and antagonists against retinoid receptor-α and retinoid receptor-X revealed that both classes of retinoid receptor can drive steroid sulphatase up-regulation. Steroid sulphatase activity fluctuates during the cell cycle, being highest around the transition from G1 to S phase. During the differentiation of HL60 cells induced by all-trans-retinoic acid or 1α,25-dihydroxyvitamin D3, there is increased conversion of 17β-oestradiol into oestrone by an oxidative 17β-hydroxysteroid dehydrogenase. Treatment of Caco-2 colon adenocarcinoma cells with all-trans-retinoic acid or 1α,25-dihydroxyvitamin D3 also increases 17β-oestradiol oxidation to oestrone. An increase in local oestrone production therefore occurs in multiple cell types following treatment with retinoids and 1α,25-dihydroxyvitamin D3. The possible involvement of locally produced oestrogenic steroids in regulating the proliferation and differentiation of myeloid cells is discussed.
Photosensitive insulation coating for a copper redistribution layer process (2014)

Redistribution on a through-silicon via (TSV) with a copper interconnection and dielectric layer is one of the key components for a silicon-based interposer. In this paper, we report lithographic and mechanical performance for a positive-tone photosensitive insulation coating, CA6001B. Minimum resolution for CA6001B is 3 μm determined by electrical measurement with a test wafer having a copper redistribution and the patterned insulation layers. The CA6001B is one of the promising dielectric coatings for interposers possessing TSV and redistribution layer (RDL) structures.
Magnetic Resonance Elastography Noninvasively Detects In Vivo Renal Medullary Fibrosis Secondary to Swine Renal Artery Stenosis (2012)

Noninvasive 3-dimensional MRE detects increased renal medullary stiffness in RAS and ARAS in vivo, which correlates with its fibrosis ex vivo and may also reflect cortical fibrosis. Hence, MRE-derived medullary stiffness can be potentially useful in detecting renal fibrosis and track disease progression.
Roughness Scaling for Edwards-Wilkinson Relaxation in Small-World Networks (2004)

Motivated by a fundamental synchronization problem in scalable parallel computing and by a recent criterion for "mean-field" synchronizability in interacting systems, we study the Edwards-Wilkinson model on two variations of a small-world network. In the first version each site has exactly one random link of strength p, while in the second one each site on average has p links of unit strength. We construct a perturbative description for the width of the stationary-state surface (a measure of synchronization), in the weak- and sparse-coupling limits, respectively, and verify the results by performing exact numerical diagonalization. The width remains finite in the limit of infinite system size for both cases, but exhibits anomalous scaling with p in the latter for d< or =2.
ChemInform Abstract: CONFORMATIONALLY DEFINED ADRENERGIC AGENTS. 8. SYNTHESIS OF CONFORMATIONALLY DEFINED ANALOGS OF NORFENFLURAMINE. A HIGHLY STEREOSPECIFIC SYNTHESIS OF AMINES FROM ALCOHOLS IN THE BENZOBICYCLO(2.2.1)HEPTENE SYSTEM (1983)

Abstract Die Grundkörper (Va) und (Xa) bzw. die stereoisomeren Trifluormethyl‐benzobicycloheptene (Ia) bis (IVa) bzw. (VIa)‐(lXa) werden mit Phthalimid in Gegenwart von Triphenylphos‐ phin und Azodicarbonsäureester zu den Phthalimiden (Ib)‐(Xb) umgesetzt, wobei allerdings nur teilweise eine stereospezifische Umsetzung erfolgt.
Design of Multi-function Audio System in Bedrooms (2007)

This paper presents design of a multi-function audio system in bedrooms. The proposed system can be installed on traditional headboards, thus has potential benefits in retrofit, convenience, and is unobtrusive. The system serves to play audio in bedrooms, can be used as a hands-free telephone system, and also provides a non invasive noise reduction system. Although the noise reduction system is capable of reducing environmental noises emanating from home appliances, real-time experiments were performed to show the capabilities of the system in reducing the more annoying snore noise. A modified twin-size headboard was used to perform experiments. Results of noise cancellation experiments with snore noise indicate a reasonable size of quiet zone with satisfactory performance achieved with the proposed low-cost system.
Computationally-Inspired Discovery of an Unsymmetrical Porous Organic Cage (2018)

&lt;p&gt;A completely unsymmetrical porous organic cage was synthesized from a C&lt;i&gt;2v &lt;/i&gt;symmetrical building block that was identified by a computational screen. The cage was formed through a 12-fold imine condensation of a tritopic C&lt;i&gt;2v &lt;/i&gt;symmetric trialdehyde with a di-topic C&lt;i&gt;2 &lt;/i&gt;symmetric diamine in a [4+6] reaction. The cage was rigid and microporous, as predicted by the simulations, with an apparent Brunauer-Emmett-Teller surface area of 578 m2 g-1. The reduced symmetry of the tritopic building block relative to its topicity meant there were 36 possible structural isomers of the cage. Experimental characterization suggests a single isomer with 12 unique imine environments, but techniques such as NMR could not conclusively identify the isomer. Computational structural and electronic analysis of the possible isomers was used to identify the most likely candidates, and hence to construct a 3-dimensional model of the amorphous solid. The rational design of unsymmetrical cages using building blocks with reduced symmetry offers new possibilities in controlling the degree of crystallinity, porosity, and solubility, of self-assembled materials.&lt;/p&gt;
Wireless Scheduling with Dominant Interferers and Applications to Femtocellular Interference Cancellation (2012)

We consider a general class of wireless scheduling and resource allocation problems where the received rate in each link is determined by the actions of the transmitter in that link along with a single dominant interferer. Such scenarios arise in a range of scenarios, particularly in emerging femto- and picocellular networks with strong, localized interference. For these networks, a utility maximizing scheduler based on loopy belief propagation is presented that enables computationally-efficient local processing and low communication overhead. Our main theoretical result shows that the fixed points of the method are provably globally optimal for arbitrary (potentially non-convex) rate and utility functions. The methodology thus provides globally optimal solutions to a large class of inter-cellular interference coordination problems including subband scheduling, dynamic orthogonalization and beamforming whenever the dominant interferer assumption is valid. The paper focuses on applications for systems with interference cancellation (IC) and suggests a new scheme on optimal rate control, as opposed to traditional power control. Simulations are presented in industry standard femtocellular network models demonstrate significant improvements in rates over simple reuse 1 without IC, and near optimal performance of loopy belief propagation for rate selection in only one or two iterations.
Highly Efficient Broadband Frequency Entangled Photon Pair Sources for Optical Quantum Applications (2020)

We developed highly efficient frequency entangled photon-pair sources using slab type waveguide QPM device for non-collinear emission, as well as ridge type waveguide chirp QPM devices for collinear emission with a 150 THz ultra-broadband.
Optimal Attack Strategies Subject to Detection Constraints Against Cyber-Physical Systems (2016)

This paper studies an attacker against a cyber-physical system (CPS) whose goal is to move the state of a CPS to a target state while ensuring that his or her probability of being detected does not exceed a given bound. The attacker's probability of being detected is related to the nonnegative bias induced by his or her attack on the CPS' detection statistic. We formulate a linear quadratic cost function that captures the attacker's control goal and establish constraints on the induced bias that reflect the attacker's detection-avoidance objectives. When the attacker is constrained to be detected at the false-alarm rate of the detector, we show that the optimal attack strategy reduces to a linear feedback of the attacker's state estimate. In the case that the attacker's bias is upper bounded by a positive constant, we provide two algorithms -- an optimal algorithm and a sub-optimal, less computationally intensive algorithm -- to find suitable attack sequences. Finally, we illustrate our attack strategies in numerical examples based on a remotely-controlled helicopter under attack.
Allelic loss of 16q23.2-24.2 is an independent marker of good prognosis in primary breast cancer. (1998)

Allelic loss, detected as a loss of heterozygosity (LOH) on the long arm of chromosome 16, is an early and frequent event in breast cancer. Despite this, the clinical significance of LOH on 16q has been very poorly studied. In this study, corresponding blood and tumor samples from 199 clinically well-characterized primary breast cancer patients were analyzed for LOH with the highly polymorphic microsatellite marker D16S511, located at 16q23.2-24.2. 61% of 168 informative tumors showed LOH. Univariate and multivariate analysis found a highly significant association between LOH at 16q23.2-24.2 and freedom from distant metastases, disease-free survival, and overall survival, respectively. No association was found with other clinical parameters such as menopausal status, tumor size, lymph node status, histopathology, and lymph node capsule invasion. This makes allelic loss of 16q23.2-24.2 an independent marker of good prognosis for primary breast cancer.
Hospital user research using new media arts (2009)

This paper presents a comparative analysis of group interaction around two display types, shared and individual, using a 'new media' arts application as a way to explore the physical technology setup for an intensive care unit in a hospital. We propose this method for laboratory settings when the research questions derive from socially complex environments, but real-world interventions are not possible. While users solve an 'interaction problem' that is posed through the 'new media' arts application for their own expressive purposes, researchers can analyse and collate the results to understand the solution space. We present a study with the bodyPaint application to address a design issue that we discovered when assessing the merits of an electronic patient record system.