gebhart/patrepeval huggingface dataset:
Exploratory nondestructive evaluation (NDE) research for advanced materials and processes: Volume 2 -- Shearography improvements. Final report, 1 July 1995--30 April 1998 (1998)

Shearographic inspection of aerospace structures has not gained wide acceptance, owing to the difficulty of interpreting shearographic images. A feature extraction method was developed that calculates surface normal curvature from input shearograms. The method can be applied in real time to provide a technician unambiguous images representing areas of locally high curvature, which will generally highlight the boundaries of flaws. Images are load independent and insensitive to part viewing angle. Analytical and experimental validation tests were completed for vacuum, vibrational and thermal loading. Recommendations are presented for system development, and for practical implementation of shearography.
Thermodynamic Properties of R23/116 Azeotropic Mixture (1996)

New measurements of critical parameters, saturated vapor pressure, saturated-liquid and saturated-vapor densities, and PVT-data for the superheated vapors of the R23/116 azeotropic mixture (46/54 mass percent) are presented. Saturated vapor pressure, saturated-liquid and saturated-vapor densities were measured over a temperature range from -40 to 10°C. PVT data for the superheated vapors were obtained on the isotherms and on the isochores by two independent experimental procedures over a temperature range from 10 to 60°C and a pressure range from 800 to 7350 kPa. The obtained results have been used for developing coefficients for a modified Martin-Hou equation of state and calculating the thermodynamic properties. NOMENCLATURE ideal gas heat capacity at P Const ideal gas heat capacity at V Const density critical density saturated liquid enthalpy vapor enthalpy pressure critical pressure PIPe, reduced pressure gas constant saturated liquid entropy vapor entropy temperature boiling point at atmospheric pressure critical temperature Tffc, reduced temperature specific volume molecular mass
Lunar Global Positioning System using L1 and L2 Lagrangian Points (2008)

This paper deals with the realization of a Lunar Global Positioning System which uses two constellations of satellites around the L1 and L2 collinear libration points of the Earth - Moon system. Analytical solutions for periodic orbits around the collinear points have been investigated in the frame of the restricted three and four body problem. Different kinds of periodic orbits and geometry configurations for the constellations have been studied in order to minimize the amount of [delta]v needed for the station keeping maneuvers, also taking into consideration the requirements of satellite visibility from the Earth and coverage of the lunar surface. Particular attention was given to the definition of geometries of the constellations that guarantee coverage of the polar regions, due to their great importance in the renewed interest in lunar exploration. A short description of the control technique used for the station keeping on the periodic orbits is provided as well.
TNP-470, AN ANTI-ANGIOGENESIS AGENT, IS A POTENT INHIBITOR OF HUMAN CD4+ T CELL PROLIFERATION (1999)

464 We have previously found that TNP-470, an angiogenesis inhibitor, attenuates the development of graft arteriosclerosis in a rat model of chronic cardiac allograft rejection. Furthermore, TNP-470 prolongs allograft survival in a model of acute cardiac allograft rejection suggesting that TNP-470 has direct immunosuppressive properties. In this study, we examined the effects of TNP-470 on human CD4+ T cell activation, cytokine production and clonal proliferation in response to allogeneic and mitogenic stimuli. TNP-470 inhibits proliferation in the human mixed lymphocyte reaction (IC50 0.2ug/ml) and inhibits the proliferative response of purified CD4+ T cells to mitogen (PHA and plate bound anti-CD3). TNP-470 does not induce cell death since proliferative responses can be partially restored by addition of recombinant IL-2 to the coculture. Furthermore, we find that TNP-470 at maximal inhibitory concentrations (10ug/ml) does not induce apoptosis within the mixed lymphocyte coculture as assessed by propidium iodide staining. TNP-470 inhibits proliferation in the MLR even when added at later time points (day 3 and day 6) suggesting that its effect is not mediated through inhibition of early T cell activation. Consistent with this interpretation we find that TNP-470 (10ug/ml) does not prevent upregulation of CD40 ligand and CD25 protein expression (by FACS analysis) on CD4+ T cells exposed to PHA (5ug/ml). The effects of TNP-470 on CD4+ T cell cytokine production were also assessed. Intracellular IL-2 and IFN-γ levels were measured in CD4+ T cells following allogeneic (MLR) and mitogenic (PHA) stimuli. Whereas cyclosporine A (1 ug/ml) inhibits CD4+ T cell IL-2, and IFN-γ production, TNP-470 treatment (1 ug/ml) did not inhibit intracellular cytokine levels. Furthermore, CsA but not TNP-470 inhibits CD4+ T cell IL-2 secretion as measured in the coculture medium by competitive ELISA. In summary TNP-470 significantly inhibits CD4+ T cell proliferation induced by allogeneic and mitogenic stimuli. This inhibition appears to be due to a direct effect on cell cycle progression rather than inhibiting early T cell activation, cytokine production or the autocrine response to IL-2. This is consistent with reports showing that TNP-470 inhibits endothelial cell proliferation and expression of specific cyclins. TNP-470 is already undergoing clinical trials in patients with malignant disease owing to its anti-angiogenic effects. We speculate that TNP-470 may be a novel antiproliferative agent for use in transplantation.
A comparison and review of three sets of classification criteria for systemic lupus erythematosus for distinguishing systemic lupus erythematosus from pure mucocutaneous manifestations in the lupus disease spectrum (2020)

Although the original purpose of the systemic lupus erythematosus (SLE) classification criteria was to distinguish SLE from other mimic diseases, and to facilitate sample selection in scientific research, they have become widely used as diagnostic criteria in clinical situations. It is not known yet if regarding classification criteria as diagnostic criteria, what problems might be encountered? This is the first study comparing the three sets of classification criteria for SLE, the 1997 American College of Rheumatology (ACR'97), 2012 Systemic Lupus International Collaborating Clinics (SLICC'12) and 2019 European League Against Rheumatism/American College of Rheumatology (EULAR/ACR'19), for their ability to distinguish patients with SLE from patients with pure mucocutaneous manifestations (isolated cutaneous lupus erythematosus without internal disease, i-CLE) in the lupus disease spectrum. 1,865 patients with SLE and 232 patients with i-CLE were recruited from a multicenter study. We found that, due to low specificity, none of the three criteria are adept at distinguishing patients with SLE from patients with i-CLE. SLICC'12 performed best among the original three criteria, but if a positive ANA was removed as an entry criterion, EULAR/ACR'19 would performed better. A review of previous studies that compared the three sets of criteria was presented in this work.
Defect-Free MOF-Based Mixed-Matrix Membranes Obtained by Corona Cross-Linking (2019)

Functionalized UiO-66 metal-organic frameworks (MOF) particles were covalently grafted with hydride-terminated poly(dimethylsiloxane) (PDMS) via postsynthetic modification. These PDMS-coated MOF particles (termed here "corona-MOF") were used in the preparation of mixed-matrix membranes (MMMs). Defect-free MMMs with weight loadings of 50% were achieved with corona-MOF particles, attributed to the improved dispersibility of the corona-MOF particles and covalent linkages between the corona-MOF particles and the polymer matrix. The PDMS MMMs showed distinct separation features in single gas permeation tests, displaying much higher CO<sub>2</sub> gas permeation with no decrease in selectivity when compared to MMMs prepared with unmodified UiO-66 particles. Single gas separation tests with CO<sub>2</sub>, N<sub>2</sub>, and propane were performed to probe the separation mechanism of the corona-MOF MMMs, demonstrating that these MMMs avoid nonideal "sieve-in-a-cage" and "plugged sieves" scenarios. Additionally, due to covalent bond formation between both the MOF and the polymer matrix in corona-MOF MMMs, particle aggregation is negligible during film curing, allowing for the formation of flexible, self-standing MMMs of <1 μm in thickness. Low quantities of polymer covalently attached to the MOF surface (<5 wt %) are sufficient to fabricate thin, defect-free, high MOF-loading MMMs.
Next Generation Chemical Agent Detection Architecture [Poster] (2021)

Sandia National Labs (SNL)-designed, portable chemical warfare agent (CWA) detection systems consist of three-stages: collection, separation, and detection. We use microfabrication technologies to miniaturize these stages and to reduce the overall size, weight, power, and (potentially) cost of the final system. Our newest system consists of a multi-dimensional separation stage and an miniature ion mobility spectrometer (IMS) detector for unprecedented system sensitivity, selectivity, and depth of target list.
Synthesis of (‐)‐Isofagomine. (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Revelations About Carotid Body Function Through its Pathological Role in Resistant Hypertension (2013)

Much recent attention has been given to the carotid body because of its potential role in cardiovascular disease states. One disease, neurogenic hypertension, characterised by excessive sympathetic activity, appears dependent on carotid body activity that may or may not be accompanied by sleep-disordered breathing. Herein, we review recent literature suggesting that the carotid body acquires tonicity in hypertension. We predict that carotid glomectomy will be a powerful way to temper excessive sympathetic discharge in diseases such as hypertension. We propose a model to explain that signalling from the 'hypertensive' carotid body is tonic, and hypothesise that there will be a sub-population of glomus cells that channel separately into reflex pathways controlling sympathetic motor outflows.
EVALUATION OF ANTIVASCULAR COMBRETASTATIN A4P EFFICACY BY USING SUPERSONIC SHEAR IMAGING TECHNIQUE OF ECTOPIC COLON CARCINOMA CT26 (2017)

International audience
Free-Carrier Effects on Zero- and One-Phonon Absorption Onsets of n-Type ZnO (2005)

Epitaxial, n -type ZnO:Ga layers grown by laser molecular-beam epitaxy were investigated by Hall-effect and spectroscopic techniques. We have studied the effects of free carriers on their optical properties in the spectral range close to the fundamental energy gap. To precisely determine the absorption onset energies, line-shape analysis of the absorption spectrum was performed using a model taking the many-body effect due to the presence of high-density electron gas into account. As a result, donor doping gives rise to a systematic blueshift of the fundamental absorption edge, consistent with the Burstein–Moss effect. The Burstein–Moss shifting behavior of ZnO:Ga is compared with that in the case of ZnO:Al. The experimental data for ZnO:Ga agree very well with the theory developed by Sernelius et al. [Phys. Rev. B 37 (1988) 10244], while the data for ZnO:Al do not. The temperature-dependent spectroscopy allowed us to investigate the effect of free carrier also on an exciton-phonon complex. It was found that, at low temperatures, the spectrum had an abrupt onset followed by two asymmetric peaks, including the anti-Stokes phonon sideband, which is explained in terms of optical singularities.
Multi-ReRAM Synapses for Artificial Neural Network Training (2019)

Metal-oxide-based resistive memory devices (ReRAM) are being actively researched as synaptic elements of neuromorphic co-processors for training deep neural networks (DNNs). However, device-level non-idealities are posing significant challenges. In this work we present a multi-ReRAM-based synaptic architecture with a counter-based arbitration scheme that shows significant promise. We present a 32×2 crossbar array comprising Pt/HfO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> /Ti/TiN-based ReRAM devices with multi-level storage capability and bidirectional conductance response. We study the device characteristics in detail and model the conductance response. We show through simulations that an in-situ trained DNN with a multi-ReRAM synaptic architecture can perform handwritten digit classification task with high accuracies, only 2% lower than software simulations using floating point precision, despite the stochasticity, nonlinearity and large conductance change granularity associated with the devices. Moreover, we show that a network can achieve accuracies > 80% even with just binary ReRAM devices with this architecture.
Learning Representations for Outlier Detection on a Budget (2015)

The problem of detecting a small number of outliers in a large dataset is an important task in many fields from fraud detection to high-energy physics. Two approaches have emerged to tackle this problem: unsupervised and supervised. Supervised approaches require a sufficient amount of labeled data and are challenged by novel types of outliers and inherent class imbalance, whereas unsupervised methods do not take advantage of available labeled training examples and often exhibit poorer predictive performance. We propose BORE (a Bagged Outlier Representation Ensemble) which uses unsupervised outlier scoring functions (OSFs) as features in a supervised learning framework. BORE is able to adapt to arbitrary OSF feature representations, to the imbalance in labeled data as well as to prediction-time constraints on computational cost. We demonstrate the good performance of BORE compared to a variety of competing methods in the non-budgeted and the budgeted outlier detection problem on 12 real-world datasets.
Measurement of the relative width difference of the B 0 ‐ B ¯ 0 $$ {B}^0\hbox{-} {\overline{B}}^0 $$ system with the ATLAS detector (2016)

This paper presents the measurement of the relative width difference d / d of the B 0 -B0 system using the data collected by the ATLAS experiment at the LHC in pp collisions at s = 7 TeV and s = 8 TeV and corresponding to an integrated luminosity of 25.2 fb -1 . The value of d / d is obtained by comparing the decay-time distributions of B 0 J/K S and B 0 J/K * 0 (892) decays. The result is d / d = (-0.11.1 (stat.) 0.9 (syst.)) 10 -2 . Currently, this is the most precise single measurement of d / d . It agrees with the Standard Model prediction and the measurements by other experiments.
Design method of surface contour for a freeform lens with wide linear field-of-view (2013)

In this paper, a design method of surface contour for a freeform imaging lens with a wide linear field-of-view (FOV) is developed. During the calculation of the data points on the unknown freeform surfaces, the aperture size and different field angles of the system are both considered. Meanwhile, two special constraints are employed to find the appropriate points that can generate a smooth and accurate surface contour. The surfaces obtained can be taken as the starting point for further optimization. An f-θ single lens with a ± 60° linear FOV has been designed as an example of the proposed method. After optimization with optical design software, the MTF of the lens is close to the diffraction limit and the scanning error is less than 1 μm. This result proves that good image quality and scanning linearity were achieved.
Integrating crop growth models with whole genome prediction through approximate Bayesian (2015)

Genomic selection, enabled by whole genome prediction (WGP) methods, is revolutionizing plant breeding. Existing WGP methods have been shown to deliver accurate predictions in the most common settings, such as prediction of across environment performance for traits with additive gene effects. However, prediction of traits with non-additive gene effects and prediction of genotype by environment interaction (GE), continues to be challenging. Previous attempts to increase prediction accuracy for these particularly difficult tasks employed prediction methods that are purely statistical in nature. Augmenting the statistical methods with biological knowledge has been largely overlooked thus far. Crop growth models (CGMs) attempt to represent the functional relationships between plant physiology and the environment in the formation of yield and similar output traits of interest. Thus, they can explain the impact of GE and certain types of non-additive gene effects on the expressed phenotype. Approximate Bayesian computation (ABC), a novel and powerful computational procedure, allows the incorporation of CGMs directly into the estimation of whole genome marker effects in WGP. Here we provide a proof of concept study for this novel approach and demonstrate its use with a simulated data set. We show that this novel approach can be considerably more accurate than the benchmark WGP method GBLUP in predicting performance in environments represented in the estimation set as well as in previously unobserved environments for traits determined by non-additive gene effects. We conclude that this proof of concept demonstrates that using ABC for incorporating biological knowledge in the form of CGMs into WGP is a very promising novel approach to improving prediction accuracy for some of the most challenging scenarios of interest to applied geneticists.
On the impact of packet spraying in data center networks (2013)

Modern data center networks are commonly organized in multi-rooted tree topologies. They typically rely on equal-cost multipath to split flows across multiple paths, which can lead to significant load imbalance. Splitting individual flows can provide better load balance, but is not preferred because of potential packet reordering that conventional wisdom suggests may negatively interact with TCP congestion control. In this paper, we revisit this “myth” in the context of data center networks which have regular topologies such as multi-rooted trees. We argue that due to symmetry, the multiple equal-cost paths between two hosts are composed of links that exhibit similar queuing properties. As a result, TCP is able to tolerate the induced packet reordering and maintain a single estimate of RTT. We validate the efficacy of random packet spraying (RPS) using a data center testbed comprising real hardware switches. We also reveal the adverse impact on the performance of RPS when the symmetry is disturbed (e.g., during link failures) and suggest solutions to mitigate this effect.
How Water in Aliphatic Solvents Directs the Interference of Chemical Reactivity in a Supramolecular System (2020)

Water is typically considered to be insoluble in alkanes. Recently, however, monomerically dissolved water in alkanes has been shown to dramatically impact the structure of hydrogen-bonded supramolecular polymers. Here, we report that water in methylcyclohexane (MCH) also determines the outcome of combining a Michael reaction with a porphyrin-based supramolecular system. In dry conditions, the components of the reaction do not affect or destabilize the supramolecular polymer, whereas in ambient or wet conditions the polymers are rapidly destabilized. Although spectroscopic investigations show no effect of water on the molecular structure of the supramolecular polymer, light scattering and atomic force microscopy experiments show that water increases the flexibility of the supramolecular polymer and decreases the polymer length. Through a series of titrations, we show that a cooperative interaction, involving the coordination of the amine catalyst to the porphyrin and complexation of the substrates to the flexible polymers invokes the depolymerization of the aggregates. Water crucially stabilizes these cooperative interactions to cause complete depolymerization in humid conditions. Additionally, we show that the humidity-controlled interference in the polymer stability occurs with various substrates, indicating that water may play a ubiquitous role in supramolecular polymerizations in oils. By controlling the amount of water, the influence of a covalent chemical process on noncovalent aggregates can be mediated, which holds great potential to forge a connection between chemical reactivity and supramolecular material structure. Moreover, our findings highlight that understanding cooperative interactions in multicomponent noncovalent systems is crucial to design complex molecular systems.
Nature of the .gamma.263 chromophore in the palytoxins (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNature of the .gamma.263 chromophore in the palytoxinsRichard E. Moore, Robert F. Dietrich, Billie Hatton, Tatsuo Higa, and Paul J. ScheuerCite this: J. Org. Chem. 1975, 40, 4, 540–542Publication Date (Print):February 1, 1975Publication History Published online1 May 2002Published inissue 1 February 1975https://doi.org/10.1021/jo00892a049RIGHTS & PERMISSIONSArticle Views96Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (399 KB) Get e-AlertsSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts