gebhart/patrepeval huggingface dataset:
Detection of sub-8-nm movements of kinesin by high-resolution optical-trap microscopy. (1996)

Kinesin is a molecular motor that transports organelles along microtubules. This enzyme has two identical 7-nm-long motor domains, which it uses to move between consecutive tubulin binding sites spaced 8 nm apart along a microtubular protofilament. The molecular mechanism of this movement, which remains to be elucidated, may be common to all families of motor proteins. In this study, a high-resolution optical-trap microscope was used to measure directly the magnitude of abrupt displacements produced by a single kinesin molecule transporting a microscopic bead. The distribution of magnitudes reveals that kinesin not only undergoes discrete 8-nm movements, in agreement with previous work [Svoboda, K., Schmidt, C. F., Schnapp, B. J. & Block, S.M. (1993) Nature (London) 365, 721-727], but also frequently exhibits smaller movements of about 5 nm. A possible explanation for these unexpected smaller movements is that kinesin's movement from one dimer to the next along a protofilament involves at least two distinct events in the mechanical cycle.
Measuring Dynamic On Resistance in GaN Transistors at MHz Frequencies (2018)

Gallium nitride (GaN) transistors are desirable for use in power electronics because of their low resistance and capacitance as compared to silicon devices. However, when switched at high frequencies, GaN transistors experience high dynamic on resistance which is both detrimental and difficult to measure. We propose a technique to measure dynamic on resistance of GaN transistors while exposing them to voltage and current waveforms that are similar to those seen in high-frequency (HF) power converters. The technique can be performed at high frequency while disambiguating loss in the output capacitance (P <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">oss</sub> ) and can be applied across frequency, temperature, and off-state voltage. The result is a lumped R <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">on</sub> value which is easily incorporated into device models to provide a more accurate basis for design, analysis, and simulation of HF converters. We apply this technique to evaluate commercial GaN transistors at 3 MHz and find that dynamic R <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">on</sub> is roughly 4-6 times the room-temperature static R <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">on</sub> values usually quoted in datasheets, with device-dependent temperature and off-state voltage dependence.
[Clinical case of the month. Intramural hematoma of the small intestine associated with anticoagulants, potentiated by interaction with cimetidine]. (1997)

Nous rapportons un cas d'hematome intramural du grele associe aux coumariniques chez un homme de 41 ans. L'effet des anticoagulants a ete favorise par la prise concomitante de cimetidine, dont l'interaction avec plusieurs medicaments a ete decrite. Le diagnostic a ete pose par l'examen tomodensitometrique abdominal et le transit du grele. Le traitement medical a entraine une resolution spontanee de l'hematome.
Visual Attributes (2017)

This unique text/reference provides a detailed overview of the latest advances in machine learning and computer vision related to visual attributes, highlighting how this emerging field intersects with other disciplines, such as computational linguistics and human-machine interaction. Topics and features: presents attribute-based methods for zero-shot classification, learning using privileged information, and methods for multi-task attribute learning; describes the concept of relative attributes, and examines the effectiveness of modeling relative attributes in image search applications; reviews state-of-the-art methods for estimation of human attributes, and describes their use in a range of different applications; discusses attempts to build a vocabulary of visual attributes; explores the connections between visual attributes and natural language; provides contributions from an international selection of world-renowned scientists, covering both theoretical aspects and practical applications.
Dynamic nonlinear behavior characterization for wideband RF transmitters using augmented Hammerstein models (2006)

This paper presents an augmented Hammerstein nonlinear model intended for characterization of the dynamic nonlinear behaviors of the wideband RF transmitter. With the substitution of the linear filter used in the conventional Hammerstein model by a weakly nonlinear filter, the augmented Hammerstein model shows a better capability to account for all of the sources of the memory effects. A transmitter prototype, which consists of a Vector Signal Generator (VSG: Agilent ESG E4438C) and an L-band 60-Watt GaAs FET push-pull amplifier, utilized in this paper for model validation. By comparing the accuracy of the augmented Hammerstein model with that of the traditional one under a two carrier WCDMA excitation condition, the validation results demonstrate the superiority of this new dynamic nonlinear model to the conventional one.
Upstream power equalization in a gigabit passive optical network (2007)

We propose a technique for achieving equalized power in upstream traffic in the gigabit passive optical network (G-PON). A simple power equalizer based on a Fabry-Perot laser diode (FP-LD) is proposed and demonstrated experimentally. By the proposed scheme, the different upstream powers can be equalized. As a result, a 20 dB dynamic upstream power range from -5 to -25 dBm, having a 1.7 dB maximal power variation, is attained. Moreover, the performance of the proposed configuration is also discussed.
A statistical model for monitoring electrical quantities (2003)

An approach to estimate of the trend, over a long time interval, of a given parameter X characterizing the operation of an electrical power system is proposed in this paper. The approach relies on a statistical model and allows to estimate the trend by processing a limited number of values of X measured at instants randomly chosen. The method proposed has been applied to both estimate the customer loads' profiles and the trend of some parameters providing information on power quality. The comparison between the estimated and the actual trends shows the good performance of the approach proposed.
Modeling, design, and demonstration of 2.5D glass interposers for 16-channel 28 Gbps signaling applications (2015)

This paper describes the modeling, design, and demonstration of high-speed differential transmission lines on a 130μm thin glass interposer with two re-distribution layers (RDL), line lengths of 1-50mm, and turn radii of 0.15-8mm for 16-channel signal transmission at 28 Gbps per channel. Next generation photonic systems such as 400 Gigabit Ethernet (400 GbE) require low power and low loss channels between photodetectors and trans-impedance amplifiers (TIA) or between laser arrays and driver ICs. Glass, with low dielectric constant and loss tangent, has higher electrical performance and channel power efficiency compared to silicon interposers. Furthermore, low surface roughness and high-dimensional stability of glass enable finer lithographic dimensions and higher interconnection density during large panel processing compared to organic interposers. Interconnection of optical and electrical ICs on 2.5D glass interposers provides the best combination of electrical and optical signal performance. For 400 GbE modules, a 16-channel bus at 28 Gbps per channel is required for communication to the backplane. Electrical modeling and simulation was performed to arrive at an appropriate design for the 16×28 Gbps I/O interface on a two-metal layer glass interposer. An ultra-thin 130μm glass interposer was fabricated using low-cost, double-side panel processing providing for a lower cost, higher performance solution compared to silicon interposers.
Farewell editorial from the founding editors (2015)

The retiring Editor-in-Chief and Deputy Editor provide a brief retrospective of the first six volumes of Biomedical Optics Express, thank the Editorial Board and OSA professional staff, and endorse the new journal leadership and the continued support of the journal by the biomedical optics community.
18F-FDG Labeling of Mesenchymal Stem Cells and Multipotent Adult Progenitor Cells for PET Imaging: Effects on Ultrastructure and Differentiation Capacity (2013)

MSCs and MAPCs can be successfully labeled with (18)F-FDG for molecular imaging purposes. The main cellular properties are not rigorously affected. TEM confirmed that the cells' ultrastructural properties are not influenced by (18)F-FDG labeling. Small-animal PET studies confirmed the intracellular location of the tracer and the possibility of imaging injected prelabeled stem cell types in vivo. Therefore, direct labeling of MSCs and MAPCs with (18)F-FDG is a suitable technique to noninvasively assess cell delivery and early retention with PET.
Direct measurement of velocity space transport in a plasma (1994)

The direct measurement of the velocity space transport of ions in a plasma is reported. Measured diffusion and convection coefficients are compared to the calculated Fokker–Planck coefficients for a fully ionized plasma. The measurements were made in a Q-machine barium plasma (Ti=Te= 0.17 eV, 5×108≤n≤8×109 cm−3) with both high and low fluctuation levels. At low fluctuation levels the measured coefficients agree with classical collision theory. Coefficients measured in the presence of large amplitude fluctuations generally are larger and have different velocity dependences. Test particle distributions are created and interrogated using the technique of optical tagging. The short-time (≪90° collision time) relaxation of the test particle distribution function was measured as a function of density and temperature of the background plasma and as a function of the velocity of the test particle distribution. The values of the convection and diffusion coefficients were extracted from these measurements. Longer time relaxations (∼90° time) also were measured.
Trends in diabetes management practices of patients from an Australian insulin‐treated diabetes register (2004)

The survey indicated that most patients were taking greater responsibility for their metabolic control, and intensive management practices and more convenient methods of administration may be contributors. Two areas of possible concern are access to dietitian services, and patient and health provider education on appropriate foot care.
Delay-Optimal Dynamic Mode Selection and Resource Allocation in Device-to-Device Communications—Part I: Optimal Policy (2015)

In this paper (Part I and Part II), we investigate the optimal dynamic mode selection and resource allocation to minimize the average end-to-end delay under a dropping probability constraint for an orthogonal frequency-division multiple-access (OFDMA) cellular network with device-to-device (D2D) communications. Different from the previous studies, which mostly focus on an infinite-backlog traffic model, we consider dynamic data arrival with nonsaturated buffers and formulate the resource control problem in D2D communications into an infinite-horizon average-reward constrained Markov decision process (CMDP) in Part I. The CMDP characterizes the dynamic interference between D2D links and cellular links based on their varying backlogged states, the dynamic route selection, and the coupled interactions between uplink and downlink resource allocations. We propose the general form of the optimal policy. In particular, it is proved that the optimal delay, respective of all feasible randomized policies, is attained by either a deterministic policy or a simple mixed policy, which randomizes between two deterministic policies. Therefore, the determination of an optimal randomized policy essentially becomes the determination of one or two deterministic policies, which can be obtained by an equivalent Bellman's equation with reduced state space. Simulation results show that the optimal policy based on the CMDP model outperforms the conventional channel-state-information-only scheme and the throughput-optimal scheme in stability sense.
Cellular Responses Induced by Zinc in Zebra Mussel Haemocytes. Loss of DNA Integrity as a Cellular Mechanism to Evaluate the Suitability of Nanocellulose-Based Materials in Nanoremediation (2021)

Zinc environmental levels are increasing due to human activities, posing a threat to ecosystems and human health. Therefore, new tools able to remediate Zn contamination in freshwater are highly recommended. Specimens of <i>Dreissena polymorpha</i> (zebra mussel) were exposed for 48 h and 7 days to a wide range of ZnCl<sub>2</sub> nominal concentrations (1-10-50-100 mg/L), including those environmentally relevant. Cellulose-based nanosponges (CNS) were also tested to assess their safety and suitability for Zn removal from freshwater. Zebra mussels were exposed to 50 mg/L ZnCl<sub>2</sub> alone or incubated with 1.25 g/L of CNS (2 h) and then removed by filtration. The effect of Zn decontamination induced by CNS has been verified by the acute toxicity bioassay Microtox<sup>®</sup>. DNA primary damage was investigated by the Comet assay; micronuclei frequency and nuclear morphological alterations were assessed by Cytome assay in mussels' haemocytes. The results confirmed the genotoxic effect of ZnCl<sub>2</sub> in zebra mussel haemocytes at 48 h and 7-day exposure time. Zinc concentrations were measured in CNS, suggesting that cellulose-based nanosponges were able to remove Zn(II) by reducing its levels in exposure waters and soft tissues of <i>D. polymorpha</i> in agreement with the observed restoration of genetic damage exerted by zinc exposure alone.
Application of Semipermeable Membrane Technology in the Measurement of Hydrocarbon Gases in Drilling Fluids (2000)

Abstract For three-quarters of a century, the detection and analysis of formation gas released into the drilling fluid and returned to surface, has been used to identify the presence of petroleum reservoirs. The value of this data source has been its immediacy. Reservoir zones can be evaluated while they are being penetrated for the first time and observations are not subject to post-drilling changes to the formation, such as mud invasion, that can limit the effectiveness of other evaluation techniques such as wireline logging. However, although the acquisition of this data is widespread in the petroleum industry, it has long had the reputation of being an unreliable source of data with inconsistent results. The inconsistencies of surface gas measurement results largely from the way that the gas is extracted from the drilling fluid. Virtually unchanged through the history of mud logging, dissolved gas is broken out of solution by applying some form of agitation to the mud. The released gas is held within a trap and transported to a remote gas analyzer by a flow of air. There are many variables and inconsistencies in this process that result in a purely qualitative gas measurement and leave important questions unanswered. Namely, how much gas is actually present in the drilling fluid and what exactly is the composition? This paper details the development of a new generation of gas measurement technology (Fig. 1) employing semipermeable membranes, providing a significant improvement in real-time wellsite gas-in-mud analysis and answers many of the previously unanswered questions. Laboratory and field results show how the semipermeable membrane functions and removes many of the inefficiencies and inconsistencies previously associated with gas extraction from the drilling fluid. Housed "within" a small probe that can be positioned directly within the returning mud stream, the semipermeable membrane provides quantitative data that benefits both formation evaluation and drilling safety. Through various stages of testing and development, the paper will illustrate how the present semipermeable membrane wellsite system signifies the starting point for a whole new generation of gas analysis devices.
3P023 Mechanism of membrane tubulation by the EFC/F-BAR domain(Hemeproteins. Electronic states. Proteins-structure and structure-function relationship,Oral Presentations) (2007)

30f d ng hisb on the
Bio-Claisen condensation catalyzed by thiolase from Zoogloea ramigera. Active site cysteine residues (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBio-Claisen condensation catalyzed by thiolase from Zoogloea ramigera. Active site cysteine residuesSatoru Masamune, Michelle A. J. Palmer, Remo Gamboni, Stuart Thompson, Jeffrey T. Davis, Simon F. Williams, Oliver P. Peoples, Anthony J. Sinskey, and Christopher T. WalshCite this: J. Am. Chem. Soc. 1989, 111, 5, 1879–1881Publication Date (Print):March 1, 1989Publication History Published online1 May 2002Published inissue 1 March 1989https://pubs.acs.org/doi/10.1021/ja00187a053https://doi.org/10.1021/ja00187a053research-articleACS PublicationsRequest reuse permissionsArticle Views330Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Stable and Variable Parts of Microbial Community in Siberian Deep Subsurface Thermal Aquifer System Revealed in a Long-Term Monitoring Study (2016)

The goal of this work was to study the diversity of microorganisms inhabiting a deep subsurface aquifer system in order to understand their functional roles and interspecies relations formed in the course of buried organic matter degradation. A microbial community of a deep subsurface thermal aquifer in the Tomsk Region, Western Siberia was monitored over the course of 5 years via a 2.7 km deep borehole 3P, drilled down to a Palaeozoic basement. The borehole water discharges with a temperature of ca. 50°C. Its chemical composition varies, but it steadily contains acetate, propionate, and traces of hydrocarbons and gives rise to microbial mats along the surface flow. Community analysis by PCR-DGGE 16S rRNA genes profiling, repeatedly performed within 5 years, revealed several dominating phylotypes consistently found in the borehole water, and highly variable diversity of prokaryotes, brought to the surface with the borehole outflow. The major planktonic components of the microbial community were <i>Desulfovirgula thermocuniculi</i> and <i>Methanothermobacter</i> spp. The composition of the minor part of the community was unstable, and molecular analysis did not reveal any regularity in its variations, except some predominance of uncultured <i>Firmicute</i>s. Batch cultures with complex organic substrates inoculated with water samples were set in order to enrich prokaryotes from the variable part of the community. PCR-DGGE analysis of these enrichments yielded uncultured <i>Firmicutes, Chloroflexi</i>, and <i>Ignavibacteriae</i>. A continuous-flow microaerophilic enrichment culture with a water sample amended with acetate contained <i>Hydrogenophilus thermoluteolus</i>, which was previously detected in the microbial mat developing at the outflow of the borehole. Cultivation results allowed us to assume that variable components of the 3P well community are hydrolytic organotrophs, degrading buried biopolymers, while the constant planktonic components of the community degrade dissolved fermentation products to methane and CO<sub>2</sub>, possibly via interspecies hydrogen transfer. Occasional washout of minor community components capable of oxygen respiration leads to the development of microbial mats at the outflow of the borehole where residual dissolved fermentation products are aerobically oxidized. Long-term community analysis with the combination of molecular and cultivation techniques allowed us to characterize stable and variable parts of the community and propose their environmental roles.
Novel architecture to boost the vertical tunneling in Tunnel Field Effect Transistors (2011)

A novel architecture to boost the performance of the Tunnel Field Effect Transistor is proposed. The improvement of drive current and subthreshold swing is achieved by inserting the channel between the source region and the gate dielectric, confining the electric field in the undoped channel region. The main feature of this architecture is to boost the vertical tunneling while suppressing the lateral tunneling path responsible for the degradation of the subthreshold swing.
DICTIONARY OF THE ECONOMIC PRODUCTS OF INDIA pages 225 to 415 (2014)

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ac Impedance Study of a Proton Exchange Membrane Fuel Cell Stack Under Various Loading Conditions (2010)

This paper presents the ac impedance study and analysis of a proton exchange membrane (PEM) fuel cell operated under various loading conditions. Ballard’s 1.2 kW Nexa™ fuel cell used for this study is integrated with a control system. The PEM fuel cell stack was operated using room air and pure hydrogen (99.995%) as input. Impedance data were collected for the fuel cell to study the behavior of the stack and groups of cells under various loads. Single cell impedance analysis was also performed for individual cells placed at different locations in the stack. The ac impedance analysis, also known as electrochemical impedance analysis, showed low frequency inductive effects and mass transport losses due to liquid water accumulation at high current densities. Results show that the stack run time to achieve steady state for impedance measurements is important. Using impedance plots, the average Ohmic resistance for the whole stack was estimated to be 41 mΩ, the same value obtained when summing the resistance value of all individual cells. Impedance analysis for groups of cells at different locations in the stack shows changes in both polarization resistance and capacitive component only in the low frequency region. At high frequencies, single cell inductive and capacitive behavior varied as a function of location in the stack. The effects of artifacts on the high frequency loop and on the high and low frequency intercept loops are also discussed.