gebhart/patrepeval huggingface dataset:
Search for long-lived stoppedR-hadrons decaying out of time withppcollisions using the ATLAS detector (2013)

An updated search is performed for gluino, top squark, or bottom squark R-hadrons that have come to rest within the ATLAS calorimeter, and decay at some later time to hadronic jets and a neutralino, using 5.0 and 22:9 fb 1 of pp collisions at 7 and 8 TeV, respectively. Candidate decay events are triggered in selected empty bunch crossings of the LHC in order to remove pp collision backgrounds. Selections based on jet shape and muon system activity are applied to discriminate signal events from cosmic ray and beam-halo muon backgrounds. In the absence of an excess of events, improved limits are set on gluino, stop, and sbottom masses for different decays, lifetimes, and neutralino masses. With a neutralino of mass 100 GeV, the analysis excludes gluinos with mass below 832 GeV (with an expected lower limit of 731 GeV), for a gluino lifetime between 10 s and 1000 s in the generic R-hadron model with equal branching ratios for decays to q " q 0 and g 0 . Under the same assumptions for the neutralino mass and squark lifetime, top squarks and bottom squarks in the Regge R-hadron model are excluded with masses below 379 and 344 GeV, respectively.
Does gastric tonometry-guided therapy reduce total mortality in critically ill patients? (2015)

Zhang and colleagues have recently published a systematic review and meta-analysis of six studies and conclude that 'gastric tonometry guided therapy can reduce total mortality in critically ill patients'. So why did gastric tonometry come and go, and what can we learn from this piece of modern history?
The dynamics and stability of lubricating oil films during droplet transport by electrowetting in microfluidic devices (2015)

The operation of digital microfluidic devices with water droplets manipulated by electrowetting is critically dependent on the static and dynamic stability and lubrication properties of the oil films that separate the droplets from the solid surfaces. The factors determining the stability of the films and preventing surface fouling in such systems are not yet thoroughly understood and were experimentally investigated in this study. The experiments were performed using a standard digital microfluidic cartridge in which water droplets enclosed in a thin, oil-filled gap were transported over an array of electrodes. Stable, continuous oil films separated the droplets from the surfaces when the droplets were stationary. During droplet transport, capillary waves formed in the films on the electrode surfaces as the oil menisci receded. The waves evolved into dome-shaped oil lenses. Droplet deformation and oil displacement caused the films at the surface opposite the electrode array to transform into dimples of oil trapped over the centers of the droplets. Lower actuation voltages were associated with slower film thinning and formation of fewer, but larger, oil lenses. Lower ac frequencies induced oscillations in the droplets that caused the films to rupture. Films were also destabilized by addition of surfactants to the oil or droplet phases. Such a comprehensive understanding of the oil film behavior will enable more robust electrowetting-actuated lab-on-a-chip devices through prevention of loss of species from droplets and contamination of surfaces at points where films may break.
Functionalized Squaraine Donors for Nanocrystalline Organic Photovoltaics (2011)

We study a family of functionalized squaraine (fSQ) donors for absorbing in the near-infrared (NIR) and green spectral regions. The NIR-absorbing materials are the symmetric molecules 2,4-bis[4-(N-phenyl-1-naphthylamino)-2,6-dihydroxyphenyl]squaraine (1-NPSQ), 2,4-bis[4-(N,N-diphenylamino)-2,6 dihydroxyphenyl]squaraine, and 2,4-bis[4-(N,N-dipropylamino)-2,6-dihydroxyphenyl]squaraine. The green light absorbing donors are asymmetric squaraines, namely, 2,4-bis[4-(N,N-diphenylamino)-2,6-dihydroxyphenyl]squaraine and 2-[4-(N,N-diisobutylamino)-2,6-dihydroxyphenyl]-4-diphenylamino]squaraine. Substitution of the arylamine groups enhances intermolecular packing, thereby increasing hole transport and the possibility of forming extended nanocrystalline junctions when annealed. Nanocrystalline solar cells based on fSQ and a C(60) acceptor have V(oc) = 1.0 V and fill factors 0.73 ± 0.01. Solar cells incorporating annealed 1-NPSQ films result in a power conversion efficiency of 5.7 ± 0.6% at 1 sun, AM1.5G illumination.
The Design of Relational Databases (1992)

Table of Contents * Introduction * An Overview of Database Design * The Entity-Relationship Model * The Relational Model * Object-Oriented Data Models * Design Principles * Integrity Constraints and Dependencies * Properties of Relational Schemas * Axiomatizations for Dependencies * Algorithms for Design Problems * Mappings between ER-Diagrams and Relational Database Schemas * Schema Transformations * Efficient Algorithms for Design Problems * Use of Example Databases in Design * Dependency Inference
Depolarization of a V-band (72 GHz) Circularly Polarized Beacon Signal Due to Tropospheric Weather Events (2020)

We present depolarization effects of various hydrometeors at the V-band (72 GHz) in Albuquerque, New Mexico during the 2018-2019 time period. The correlation between rain rate and the degradation of the cross-polarization discrimination (XPD) is calculated. The average XPD will first be found using clear sky cases and then deviations from that value will be calculated using cases where precipitous hydrometeors were present. The preliminary results presented here will contribute to an increased understanding of depolarization effects at extremely high frequencies (EHF, 30-300 GHz).
CFTR gene variants: a predisposition factor to aquagenic palmoplantar keratoderma (2019)

International audience
Adaptive Artificial Neural Network-Coupled LDPC ECC as Universal Solution for 3-D and 2-D, Charge-Trap and Floating-Gate NAND Flash Memories (2019)

Adaptive artificial neural network (ANN)coupled low-density parity-check (LDPC) error-correcting code (ECC) (ANN-LDPC ECC) is proposed to increase acceptable errors for various NAND flash memories. The proposed ANN-LDPC ECC can be the universal solutions for 3-D and 2-D, charge-trap and floating-gate NAND flash memories. In 3-D NAND flash, lateral charge migration, vertical charge de-trap, inter floating-gate capacitive coupling noise, and inter word-line variations cause errors. On the other hand, in 2-D NAND flash, the charge de-trap and the harsh inter floating-gate capacitive coupling of adjacent word-lines and bit-lines cause errors. To solve these reliability problems, the proposed ANN automatically and adaptively compensates for complex memory cell errors. Moreover, the proposed ANNLDPC can reproduce the dynamic endurance and data-retention time dependence of errors. In addition, this paper evaluates the impacts of the chip-to-chip variations on the proposed ANN-LDPC. The proposed ANN-LDPC is implemented in the storage controller and can precisely and adaptively estimate bit-error rate (BER) and log-likelihood ratio (LLR). By using the precise LLR, LDPC decoder effectively corrects errors. As a result, ANN-LDPC extends the acceptable data-retention time by over 76× and 45× compared with conventional Bose-Chaudhuri-Hocquenghem (BCH) ECC in 3-D and 2-D triple-level cell (TLC) NAND flash memories, respectively.
Supplementary Figures 1 through 6 from Synergistic Combination of Novel Tubulin Inhibitor ABI-274 and Vemurafenib Overcomes Vemurafenib Acquired Resistance in BRAF<sup>V600E</sup> Melanoma (2023)

&lt;p&gt;PDF - 476K, Figure S1. Establishment of vemurafenib-resistant A375 melanoma cell line A375RF21 from its parental A375 cell line using chronic selection over 3 months with increasing concentrations of vemurafenib; Figure S2. Anti-phospho-histone H3 and PI (propidium iodide) bivariate staining cell cycle analysis on vemurafenib-resistant cells; Figure S3. In vitro dose-response curves (n = 5) of each combination in A375 and A375RF21 cells; Figure S4. Major vemurafenib resistance mechanisms in A375RF21 cells are the over-expression of PDGFβ and the activations of the PI3K-AKT pathway; Figure S5. Effect of single agent and combination treatment on purified-protein based tubulin polymerization assay (n = 3); Figure S6. In vitro growth curve for A375 and vemurafenib-resistant subline A375RF21 cells.&lt;/p&gt;
SLAs Decomposition for Network Slicing: A Deep Neural Network Approach (2022)

5G is a multi-service network supporting a range of verticals with a diverse set of requirements. Network slicing enables the creation and operation of multiple logical networks over the shared network infrastructure, tailored to the requirements of a particular service type with agreed upon Service Level Agreement (SLA). A network slice may span different parts of the network (i.e., access, core, and transport network) and could be deployed across multiple operators and infrastructure providers. Therefore, the end-to-end SLA associated with a network slice should be decomposed in portions attributed to each of these domains. We assume a two-level management architecture consisting of an end-to-end service orchestrator responsible for the lifecycle management of the network service and domain controllers that are in charge of instantiating parts of the slice in their respective domains. In this context the orchestrator is responsible for decomposing the SLA, without detailed knowledge of the state of the resources in each of the domains. The orchestrator is only aware of the responses of the domain controllers to previous requests and captures this knowledge in a risk model associated with each domain. In this study, we propose an approach for decomposing the end-to-end SLA adopting neural network-based risk models. We discuss several approaches that utilize the monotonicity prior, such that the SLA can be adequately decomposed even when the number of historical data is low. An empirical study on a synthetic multidomain dataset demonstrates the efficiency of our approach.
Electrically tunable efficient broad-band fiber filter (1999)

We demonstrate a new type of fiber-optic electrically tunable filter that enables a tuning range of 60 mm with an electrical power of 0.17 W, corresponding to a tuning efficiency of approximately 320 nm/W. The device is based on a metal coated long-period fiber grating written in a specially designed "air-clad" fiber that is filled with a polymer whose index of refraction is a sensitive function of temperature. Resistive heating, caused by current flowing through the metal coating, heats the polymer and induces changes in its index of refraction; these changes induce shifts in the position of the attenuation dip associated with the long-period grating. The air-clad structure has two benefits: (1) it enables the introduction of temperature sensitive materials into the fiber thus enabling power efficient operation of the device and (2) ensures that the cladding modes are insensitive to the surrounding environment and thus are unaffected by the metal coating on the surface of the fiber.
Inherited duplications of PPP2R3B predispose to nevi and melanoma via a C21orf91-driven proliferative phenotype (2021)

This work confirms the power of a rare disease approach, identifying a previously unreported copy-number change predisposing to melanocytic neoplasia, and discovers C21orf91 as a potentially targetable hub in the control of phenotype switching.
Thermoelectric Properties of RF-Sputtered SiGe Thin Film for Hydrogen Gas Sensor (2004)

Phosphorus-doped Si 0.8 Ge 0.2 thin films were deposited on the Si 3 N 4 /SiO 2 /Si substrate by the RF sputtering. Thermal annealing was carried out to crystallize as-deposited, amorphous-like SiGe thin films. With increasing annealing temperature and time, the crystallization of the SiGe thin films progressed, resulting in a high carrier mobility and a large absolute value of Seebeck coefficient. The SiGe thin film deposited on the Si 3 N 4 /SiO 2 /Si substrate and then annealed at 850°C for 5 h at an argon flow rate of 150 cc/min showed a Seebeck coefficient of -198 µV/K, a Hall mobility of 10.54 cm 2 /Vs, a carrier concentration of 1.1×10 18 cm -3 at 100°C. The thermoelectric hydrogen sensor with the SiGe thin film annealed at 850°C for 5 h showed a voltage signal of 5.81 mV, a catalyst activity of 16.17°C and a response time, corresponding to 90% voltage signal of 50 s for 3% H 2 in air. The sensor operating at 100°C detected hydrogen in air at concentrations from 0.01 to 3%, and showed a good linearity between voltage signal and gas concentration.
RTD analysis of a novel Taylor‐Couette flow device for blood detoxification (1999)

Abstract Heparin is an anticoagulant used in extracorporeal procedures such as hemodialysis and open heart surgery. Unfortunately, heparin may induce potentially fatal complications in patients at high risk of bleeding. The use of an immobilized heparinase I reactor makes heparin therapy safer, but the design of a safe and efficient reactor for medical use had been a significant problem. A novel reactor, based on simultaneous separation‐ reaction and Taylor‐Couette flow, was designed and successfully tested in vitro with human blood and ex vivo in sheep. The objective of this study was to understand the flow dynamics in the reactor in order to predict and optimize heparin neutralization. Residence‐time distribution studies were performed and a mathematical model was developed. The model was able to predict experimental conversions within a mean relative error of 5.5%. Bypass flow through the reactive section was also predicted.
A Portable Molecularly Imprinted Sensor for On-Site and Wireless Environmental Bisphenol A Monitoring (2022)

The detection of pollutant traces in the public and environmental waters is essential for safety of the population. Bisphenol A (BPA) is a toxic chemical widely used for the production of food storage containers by plastic industries to increase the storage ability. However, the insertion of BPA in water medium leads to serious health risks. Therefore, the development of low-cost, practical, sensitive, and selective devices to monitor BPA levels on-site in the environment is highly needed. Herein, for the first time, we present a homemade portable potentiostat device integrated to a laser-scribed graphene (LSG) sensor for BPA detection as a practical environmental pollutant monitoring tool. Recently, there has been an increasing need regarding the development of graphene-based electrochemical transducers (e.g., electrodes) to obtain efficient biosensing platforms. LSG platform is combined with molecularly imprinted polymer (MIP) matrix. LSG electrodes were modified with gold nanostructures and PEDOT polymer electrodeposition to create a specific MIP biomimetic receptor for ultrasensitive BPA detection. The sensing device has a Bluetooth connection, wirelessly connected to a smartphone providing high sensitivity and sensitivity (LOD: 3.97 nM in a linear range of .01-10 µM) toward BPA. Two commercial bottled water samples, tap water, commercial milk, and baby formula samples have been used to validate the reliability of the portable sensor device.
Elektroenzymatische Synthese mit ionischen Flüssigkeiten (2008)

The electrochemical generation, respectively regeneration of redox equivalents represents an interesting alternative to the for this purpose usually applied methods. However, this method has some drawbacks, which make their application as industrial processes economically unfeasible. Especially, the by now very low achieved productivities, which result from the low conductivity of the used aqueous reaction media, represent a major challenge. Therefore within this thesis, the potential of ionic liquids as conducting salts for electroenzymatic synthesis was explored. For three different, but typical electroenzymatic syntheses, influences of ionic liquids on the activity and stability of the biocatalyst, on the solubility of the used substrates, on the conductivity of the reaction medium as well as on the involved electrochemical reaction step were investigated. These examples showed that not only the conductivity of the reaction medium was improved, but also some other advantages can be achieved by the application of ionic liquids. Additionally, it is possible to stabilize the biocatalyst and reduced nicotinamide cofactors and to increase the solubility of hardly water soluble substrates. Depending on the reaction system, this results in optimized space time yields and turnover frequencies for the applied mediators and in addition to that, in improved biocatalyst utilizations. Moreover, for one of the reactions a comparison of conventional conducting salts and ionic liquids was drawn, showing clear benefits for the usage of ionic liquids. Furthermore, it was possible to arrange a generic scheme for the influence of different cations and anions from ionic liquids on the performance of the used biocatalysts.
An online evolutionary approach to developing internet services (2002)

High dependability in Internet services is a difficult challenge: new features are constantly added, the systems are being scaled to support more users, and these systems are subject to unpredictable workloads and inputs. To deal with these challenges, operators must constantly adapt and evolve their system in response to its dynamic behavior. We argue that this online evolution is necessary for the development and deployment of dependable Internet services. This paper presents a conceptual model of online evolution consisting of three phases---monitoring, analysis, and modification---and present techniques we have found useful in speeding the process of online evolution.
An argumentation-based approach to handling trust in distributed decision making (2013)

Our work aims to support decision making in situations where the source of the information on which decisions are based is of varying trustworthiness. Our approach uses formal argu-mentation to capture the relationships between such informa-tion sources and conclusions drawn from them. This allows the decision maker to explore how information from particu-lar sources impacts the decisions they have to make. We de-scribe the formal system that underlies our work, and a pro-totype implementation of that system, applied to a problem from military decision making.
The therapeutic potential of mesenchymal stem cell‐derived extracellular vesicles (2013)

Extracellular vesicles (EVs), membrane vesicles that are secreted by a variety of mammalian cell types, have been shown to play an important role in intercellular communication. The contents of EVs, including proteins, microRNAs, and mRNAs, vary according to the cell type that secreted them. Accordingly, researchers have demonstrated that EVs derived from various cell types play different roles in biological phenomena. Considering the ubiquitous presence of mesenchymal stem cells (MSCs) in the body, MSC-derived EVs may take part in a wide range of events. In particular, MSCs have recently attracted much attention due to the therapeutic effects of their secretory factors. MSC-derived EVs may therefore provide novel therapeutic approaches. In this review, we first summarize the wide range of functions of EVs released from different cell types, emphasizing that EVs echo the phenotype of their parent cell. Then, we describe the various therapeutic effects of MSCs and pay particular attention to the significance of their paracrine effect. We then survey recent reports on MSC-derived EVs and consider the therapeutic potential of MSC-derived EVs. Finally, we discuss remaining issues that must be addressed before realizing the practical application of MSC-derived EVs, and we provide some suggestions for enhancing their therapeutic efficiency.
Modifiable Risk Factors and Residual Risk Following Coronary Revascularization (2021)

Patients who have undergone revascularization procedures remain at elevated risk for MACE, and inadequately controlled risk factors are prevalent in follow-up. This highlights the need for aggressive secondary prevention strategies and implementation of programs to optimize postrevascularization care.
HΛ3 and H‾Λ‾3 lifetime measurement in Pb–Pb collisions at sNN=5.02 TeV via two-body decay (2019)

An improved value for the lifetime of the (anti-)hypertriton has been obtained using the data sample of Pb-Pb collisions at s NN = 5.02 TeV collected by the ALICE experiment at the LHC. The (anti-)hypertriton has been reconstructed via its charged two-body mesonic decay channel and the lifetime has been determined from an exponential fit to the dN/d(ct) spectrum. The measured value, = 242 +34 -38 (stat.) 17 (syst.) ps, is compatible with representative theoretical predictions, thus contributing to the solution of the longstanding hypertriton lifetime puzzle.
Standardized Protocol for Hemodialysis Vascular Access Assessment: The Role of Ultrasound and ColorDoppler (2018)

The creation of a step-by-step protocol may simplify the multidisciplinary management of VA, its monitoring and the early diagnosis of its complications.
Detection of mTBI in pediatric populations using BrainCheck, a tablet-based cognitive testing software (2020)

Abstract Aim Despite its high frequency of occurrence, mild traumatic brain injury (mTBI), or concussion, is difficult to recognize and diagnose, particularly in pediatric populations. Conventional methods to diagnose mTBI primarily rely on clinical questionnaires and sometimes include imaging such as computed tomography (CT) or pencil and paper neuropsychological testing. However, these methods are time consuming, require administration/interpretation from health professionals, and lack adequate test sensitivity and specificity. We explore the use of BrainCheck, a computerized neurocognitive test that is available on iPad, iPhone or computer desktop, for mTBI assessment. The BrainCheck battery consists of 6 gamified traditional neurocognitive tests that assess areas of cognition vulnerable to mTBI such as attention, processing speed, executing functioning, and coordination. Methods We administered BrainCheck to 10 participants diagnosed with mTBI at the emergency department (ED) of Children’s hospital within 96 hours of admittance to the ED, and 126 normal controls at a local high school. Statistical analysis included Chi-Square tests, Analysis of Variance (ANOVA), independent sample t-tests, and Hochberg tests to examine differences between mTBI, diagnoses by current gold standard clinical exam, and control groups on each assessment in the battery. Significant metrics from these assessments were used to build a logistic regression model that distinguishes mTBI from non-mTBI participants. Results BrainCheck was able to detect significant differences in coordination, Flanker, Stroop, Digital Symbol, Immediate/Delayed recall and recognition assessments between normal people and mTBI patients. Receiver operator score (ROC) analysis of our logistic regression model found a sensitivity of 84% and specificity of 80%. Conclusions BrainCheck has potential in distinguishing mTBI from non-mTBI participants, by providing a shorter, gamified test battery to assess cognitive function after brain injury, while also providing a method for tracking recovery with the opportunity to do so remotely from a patient’s home.
Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib (2015)

NCT01425853.