gebhart/patrepeval huggingface dataset:
ERP Correlates of Proactive and Reactive Cognitive Control in Treatment-Naïve Adult ADHD (2016)

This study investigated whether treatment naïve adults with Attention Deficit Hyperactivity Disorder (ADHD; n = 33; 19 female) differed from healthy controls (n = 31; 17 female) in behavioral performance, event-related potential (ERP) indices of preparatory attention (CueP3 and late CNV), and reactive response control (Go P3, NoGo N2, and NoGo P3) derived from a visual cued Go/NoGo task. On several critical measures, Cue P3, late CNV, and NoGo N2, there were no significant differences between the groups. This indicated normal preparatory processes and conflict monitoring in ADHD patients. However, the patients had attenuated Go P3 and NoGoP3 amplitudes relative to controls, suggesting reduced allocation of attentional resources to processes involved in response control. The patients also had a higher rate of Go signal omission errors, but no other performance decrements compared with controls. Reduced Go P3 and NoGo P3 amplitudes were associated with poorer task performance, particularly in the ADHD group. Notably, the ERPs were not associated with self-reported mood or anxiety. The results provide electrophysiological evidence for reduced effortful engagement of attentional resources to both Go and NoGo signals when reactive response control is needed. The absence of group differences in ERP components indexing proactive control points to impairments in specific aspects of cognitive processes in an untreated adult ADHD cohort. The associations between ERPs and task performance provided additional support for the altered electrophysiological responses.
Robust Highly-Connected Direct Interconnection Network Topologies. (2003)

The histochemical and ultrastructural study of muscle biopsies of two patients with a chronic muscle weakness and wasting showed particular changes in muscle fibers: (1) peripheral lined vacuoles, containing whorls of membranes and cytoplasmic debris; (2) collections of intranuclear and intrasarcoplasmic tubular filaments (16-18 nm in external diameter and 6.5 nm in inner diameter). These changes are characteristic of a rare muscle disorder termed inclusion body myositis; its individuality is favoured by the present study. The resemblance of the tubular filaments to myxovirus nucleocapsid has been suggested by various authors but attempts to isolate the virus were unsuccessful in several reported cases as well as in those here presented. This does not exclude a viral origin of the disease. The similarity of the tubular filaments to thick myofilaments has been invoked by others, but has not been demonstrated. At the present the nature of the abnormal filaments remains unknown.
Chalcogen and Hydrogen Bonds at the Periphery of Arylhydrazone Metal Complexes (2022)

Ligands comprising an intramolecular resonance-assisted hydrogen bond (RAHB) and an intramolecular resonance-assisted chalcogen bond (RAChB) have been used to form Cu(II), Ag(I), and Cd(II) metal complexes. Both interactions undergo major changes on ligand binding to the metal even though metal-ligand binding does not directly involve either interactions. In fact, the RAChB synthon can act as an intermolecular H-bond donor or acceptor, is involved in intramolecular coordination-coupled proton transfer, or exhibits an ionic pattern.
New benzoyl urea derivatives as novel NR2B selective NMDA receptor antagonists. (2006)

A novel series of benzoyl urea derivatives was prepared and identified as NR2B selective NMDA receptor antagonists. The influence of the substitution of the piperidine ring on the biological activity of the compounds was studied. Compound 9 was active in the formalin test in mice.
Tyrosines in the MUC1 Cytoplasmic Tail Modulate Transcription via the Extracellular (2006)

Much of the ability of the MUC1 oncoprotein to foster tumorigenesis and tumor progression likely originates from the interaction of its cytoplasmic tail with proteins involved in oncogenic signaling. Many of these interactions are regulated by phosphorylation, as the cytoplasmic tail contains seven highly conserved tyrosines and several serine/threonine phosphorylation sites. We have developed a cell line – based model system to study the effects of tyrosine phosphorylation on MUC1 signaling, with particular emphasis on its effects on gene transcription. COS-7 cells, which lack endogenous MUC1, were stably infected with wild-type MUC1 or a MUC1 construct lacking all seven tyrosines (MUC1 Y0) and analyzed for effects on transcription
Multidisciplinary Research in Smart Composite Structures (2000)

This is the final report of the MURI program entitled Multidisciplinary Research in Smart Composite Structures. The approach taken by this program to overcome shortcomings of existing smart structures technology was that of Vertical technology Integration. This approach has allowed the development of technology at all critical levels of functional integration, from fundamental material studies to complex controlled structures. This approach enabled a complete lowdown of applications' requirements to serve as focal points for fundamental research, and it enabled capabilities flowup to application performance which can be used as a metric to evaluate the important capabilities at each level. The research conducted by the members of this program was a coordinated effort to address issues at the materials, devices and applications levels, and the results obtained in this program represent significant steps in that direction.
Codelivery of Dual Drugs from Polymeric Micelles for Simultaneous Targeting of Both Cancer Cells and Cancer Stem Cells (2015)

The combination of Gem M and Phen M may be potentially used in lung cancer therapy.
Critical Evaluation of the 5-Day Metyrapone Test (1977)

Different parameters of the response to the 5-day metyrapone test were evaluated for their diagnostic accuracy in tests given to 58 children and adolescents as part of an investigation for short stature. Insulin test, vasopressin test and ACTH test were used for diagnostic reference. A log transformation of the data was clearly appropriate. The maximal daily excretion of 17-ketogenic steroids was distinctly positively correlated with the basal excretion. Consequently, the most correct parameter of the response is the SD score of the deviation of the maximal excretion from the regression of the maximal excretion on the basal excretion in the reference population. This parameter, 'relative maximal excretion' was shown to be the diagnostically most accurate index of the response of 11 parameters studied.
Materials, structures, and devices for high-speed electronics (1992)

Advances in materials, devices, and instrumentation made under this grant began with ex-situ null ellipsometric measurements of simple dielectric films on bulk substrates. Today highly automated and rapid spectroscopic ellipsometers are used for ex-situ characterization of very complex multilayer epitaxial structures. Even more impressive is the in-situ capability, not only for characterization but also for the actual control of the growth and etching of epitaxial layers. Spectroscopic ellipsometry has expanded from the research lab to become an integral part of the production of materials and structures for state of the art high speed devices. Along the way, it has contributed much to our understanding of the growth characteristics and material properties. The following areas of research are summarized: Si3N4 on GaAs, null ellipsometry; diamondlike carbon films; variable angle spectroscopic ellipsometry (VASE) development; GaAs-AlGaAs heterostructures; Ta-Cu diffusion barrier films on GaAs; GaAs-AlGaAs superlattices and multiple quantum wells; superconductivity; in situ elevated temperature measurements of III-V's; optical constants of thermodynamically stable InGaAs; doping dependence of optical constants of GaAs; in situ ellipsometric studies of III-V epitaxial growth; photothermal spectroscopy; microellipsometry; and Si passivation and Si/SiGe strained-layer superlattices.
Effect of Abscission Zone Formation on Orange (Citrus sinensis) Fruit/Juice Quality for Trees Affected by Huanglongbing (HLB) (2018)

Orange trees affected by huanglongbing (HLB) exhibit excessive fruit drop, and fruit loosely attached to the tree may have inferior flavor. Fruit were collected from healthy and HLB-infected ( Candidatus liberibacter asiaticus) 'Hamlin' and 'Valencia' trees. Prior to harvest, the trees were shaken, fruit that dropped collected, tree-retained fruit harvested, and all fruit juiced. For chemical analyses, sugars and acids were generally lowest in HLB dropped (HLB-D) fruit juice compared to nonshaken healthy (H), healthy retained (H-R), and healthy dropped fruit (H-D) in early season (December) but not for the late season (January) 'Hamlin' or 'Valencia' except for sugar/acid ratio. The bitter limonoids, many flavonoids, and terpenoid volatiles were generally higher in HLB juice, especially HLB-D juice, compared to the other samples. The lower sugars, higher bitter limonoids, flavonoids, and terpenoid volatiles in HLB-D fruit, loosely attached to the tree, contributed to off-flavor, as was confirmed by sensory analyses.
An Adaptable Framework for Factors Contributing to Medication Adherence: Results from a Systematic Review of 102 Conceptual Frameworks (2021)

PROSPERO Identifier: CRD42020181316.
Self-Assembled Materials Systems and Devices for R-FLICS (2004)

Electro-optic (EO) modulators based on multilayer self-assembled superlattices (SAS) from wet deposition, and from vapor phase deposition have been designed, fabricated, and characterized. Two-step wet chemical protection-deprotection approach for the growth of SAS was used for the fabrication of electro-optic modulators. With this process the SAS film can he grown at a rate of about 40 minutes per bilayer, and it is at least one order of magnitude more rapid than previous three-step deposition method. Novel approaches of self-assembly via vapor phase deposition were investigated for the growth of EO active DTPT, and PEPCOOH thin films. The EO active thin films exhibit strong second harmonic generation and EO modulation effects without external electric field poling. Promising electro-optic materials were used for the grown of EO thin films from vapor phase, and prototype electro-optic modulators were fabricated and tested by integrating the intrinsically acentric self-assembled thin films with low-loss polymeric layers and semiconductor substrates.
Processes forming Gas, Tar, and Coke in Cellulose Gasification from Gas‐Phase Reactions of Levoglucosan as Intermediate (2015)

The gas-phase pyrolysis of levoglucosan (LG), the major intermediate species during cellulose gasification, was studied experimentally over the temperature range of 400-900 °C. Gaseous LG did not produce any dehydration products, which include coke, furans, and aromatic substances, although these are characteristic products of the pyrolysis of molten LG. Alternatively, at >500 °C, gaseous LG produced only fragmentation products, such as noncondensable gases and condensable C1 -C3 fragments, as intermediates during noncondensable gas formation. Therefore, it was determined that secondary reactions of gaseous LG can result in the clean (tar- and coke-free) gasification of cellulose. Cooling of the remaining LG in the gas phase caused coke formation by the transition of the LG to the molten state. The molecular mechanisms that govern the gas- and molten-phase reactions of LG are discussed in terms of the acid catalyst effect of intermolecular hydrogen bonding to promote the molten-phase dehydration reactions.
A Review of Charging Algorithms for Nickel and Lithium Battery Chargers (2011)

Battery-charging algorithms can be used for either single- or multiple-battery chemistries. In general, single-chemistry chargers have the advantages of simplicity and reliability. On the other hand, multichemistry chargers, or “universal battery chargers,” provide a practical option for multichemistry battery systems, particularly for portable appliances, but they have some limitations. This paper presents a review of some charging algorithms for major batteries, i.e., nickel–cadmium, nickel–metal–hydride, and lithium-ion batteries for single- and multiple-chemistry chargers. A comparison between these algorithms in terms of their charging schemes and charge termination techniques is included. In addition, some trends of recent chargers development are presented.
PLL design for a 500 MB/s interface (1993)

When operating pins at high data rates, the key problem is to control timing skews (both on- and off-chip) so data on the pins can be read in a short time. The problem of external skews is solved by a clocking scheme where clock and data signals travel the same distance between the sender and receiver so that there is little skew on the 600-mV/sub pp/ external signals. There are two clocks: one for incoming data (RxClk) and one for outgoing data (TxClk). A PLL (phase-locked loop) generates the properly skewed internal clocks to operate the bus. The PLL consists of one main loop and two fine loops (one each for the receive and transmit clocks). The main loop is a VCO (voltage-controlled oscillator) based second-order loop using a 6-stage, small-swing, differential ring oscillator VCO. It is locked to the incoming RxClk after it is amplified to full CMOS levels. VCO and input clock frequency are halved to allow the phase/frequency detector more time to settle. The fine loop delays the internal clock (relative to the input RxClk) by an amount that causes the sampler to produce high and low outputs with precisely equal frequency, thereby compensating for sampler setup time.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Cavitation in a soft porous material (2022)

We study the collapse and expansion of a cavitation bubble in a deformable porous medium. We develop a continuum-scale model that couples compressible fluid flow in the pore network with the elastic response of a solid skeleton. Under the assumption of spherical symmetry, our model can be reduced to an ordinary differential equation that extends the Rayleigh-Plesset equation to bubbles in soft porous media. The extended Rayleigh-Plesset equation reveals that finite-size effects lead to the breakdown of the universal scaling relation between bubble radius and time that holds in the infinite-size limit. Our data indicate that the deformability of the porous medium slows down the collapse and expansion processes, a result with important consequences for wide-ranging phenomena, from drug delivery to spore dispersion.
ChemInform Abstract: Novel Terphenyls as Selective Cyclooxygenase‐2 Inhibitors and Orally Active anti‐Inflammatory Agents. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
CRAWDAD dataset tools/analyze/802.11/Wit (v. 2006-09-01) (2006)

Wit is a non-intrusive tool that builds on passive monitoring to analyze the detailed MAC-level behavior of operational wireless networks.
A Review of the Terahertz Conductivity and Photoconductivity of Carbon Nanotubes and Heteronanotubes (2021)

Terahertz (THz) spectroscopy is an ideal non‐contact and non‐destructive technique that probes the electrical conductivity of nanomaterials. This review presents the current status of research in the THz properties of quasi‐1D materials, such as nanotubes (NTs) and NT heterostructures. Detailed descriptions of THz experimental methods (THz time‐domain spectroscopy, optical pump‐THz probe spectroscopy) and conductivity extraction methods are presented along with the physical models (Drude, plasmon, effective medium theories, etc.) supporting them. Optoelectronic applications, such as optical modulators, switches, and shielding devices, are discussed and illustrate a bright future for these materials.
Supplementary Movie 4 from Loss-of-Function Mutations in TRAF7 and KLF4 Cooperatively Activate RAS-Like GTPase Signaling and Promote Meningioma Development (2023)

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Data from "Extremely Small Twist Elastic Constants in Lyotropic Nematic Liquid Crystals" (2020)

Depolarized dynamic light scattering (DDLS) data, fit routine fitting results
EPR and modelling studies of hydrogen-abstraction reactions relevant to polyolefin cross-linking and grafting chemistryElectronic supplementary information (ESI) available: computed 3D structures of the transition states of hydrogen abstraction from 2,4-dimethylpentane by tert-butoxyl radical. “1 ry24dmp.pdb”: H-abstraction from the methyl group (to generate a primary radical). “2ry24dmp.pdb”: H-abstraction from the central methylene group (to generate a secondary radical). “3 ry24dmp.pdb”: H-abstraction from the methine group (to generate a tertiary radical). See http://www.rsc.org/suppdata/ob/b2/b212543a/ (2003)

EPR spectroscopy has been employed to study directly the selectivity of hydrogen-atom abstraction by some alkoxyl radicals from a variety of linear and branched alkanes, as well as linear alkenes, chosen as models for low molecular-weight polyolefin cross-linking systems. In situ thermal and photolytic approaches, as well as spin-trapping, have been employed to provide information relating to an accessible temperature range of 233-453 K. in part to mimic conditions relevant to melt processing of polyolefins. Rate constants (in the range 3 x 10(3)-3.7 x 10(5) dm3 mol-1 s-1 per hydrogen) have been determined for C-H abstraction at room temperature. Radical selectivity is largely governed by enthalpic effects (modelled via bond dissociation energy calculations and kinetic analysis). Direct evidence has been obtained for lack of reactivity, as a result of unfavourable steric interactions, for the secondary and tertiary C-H bonds in 2,4-dimethylpentane and 2,4,6-trimethylheptane, models for polypropylene. This has been rationalized via free-energy calculations using DFT.
Effect of deposition rate on the morphology of CdS films deposited in an ammonia free solution (2013)

A. CARRILLO-CASTILLO, F. S. AGUIRRE-TOSTADO, A. SALASVILLASENOR, I. MEJIA, B. E. GNADE, M. SOTELO-LERMA, M.A. QUEVEDO-LOPEZ . Centro de Investigacion en Materiales Avanzados, S. C. Alianza Norte 202, Parque de Investigacion e Innovacion Tecnologica, Apodaca, Nuevo Leon, C.P. 666000, Mexico Department of Materials Science and Engineering, The University of Texas at Dallas. 800 West Campbell Rd, Richardson TX 75083, USA Departamento de Investigacion en Polimeros y Materiales. Universidad de Sonora. Hermosillo, Sonora, C.P. 83000, Mexico
A novel class of phenylpyrazolone-sulphonamides rigid synthetic anticancer molecules selectively inhibit the isoform IX of carbonic anhydrases guided by molecular docking and orbital analyses (2023)

All the previously reported phenylpyrazoles as carbonic anhydrase inhibitors (CAIs) were found to have small sizes and high levels of flexibility, and hence showed low selectivity profiles toward a particular isoform of CA. Herein, we report the development of a more rigid ring system bearing a sulfonamide hydrophilic head and a lipophilic tail to develop novel molecules that are suggested to have a better selectivity toward a special CA isoform. Accordingly, three novel sets of pyrano[2,3-<i>c</i>]pyrazoles attached with sulfonamide head and aryl hydrophobic tail were synthesized to enhance the selectivity toward a specific isoform of human carbonic anhydrases (<i>h</i>CAs). The impact of both attachments on the potency and selectivity has been extensively discussed in terms of <i>in vitro</i> cytotoxicity evaluation under hypoxic conditions, structure-activity relationship and carbonic anhydrase enzyme assay. All of the new candidates displayed good cytotoxic activities against breast and colorectal carcinomas. Results of the carbonic anhydrase enzyme assay demonstrated the preferential of compounds <b>22</b>, <b>24</b> and <b>27</b> to inhibit the isoform IX of <i>h</i>CAs selectively. Wound-healing assay has also been performed and revealed the potential of <b>27</b> to decrease the wound closure percentage in MCF-7 cells. Molecular docking and molecular orbital analysis have finally been conducted. Results indicate the potential binding interactions of <b>24</b> and <b>27</b> with several crucial amino acids of the <i>h</i>CA IX.Communicated by Ramaswamy H. Sarma.
Log files: an extended file service exploiting write-once storage (1987)

A log service provides efficient storage and retrieval of data that is written sequentially (append-only) and not subsequently modified. Application programs and subsystems use log services for recovery, to record security audit trails, and for performance monitoring. Ideally, a log service should accommodate very large, long-lived logs, and provide efficient retrieval and low space overhead. In this paper, we describe the design and implementation of the Clio log service. Clio provides the abstraction of log files : readable, append-only files that are accessed in the same way as conventional files. The underlying storage medium is required only to be append-only; more general types of write access are not necessary. We show how log files can be implemented efficiently and robustly on top of such storage media—in particular, write-once optical disk. In addition, we describe a general application software storage architecture that makes use of log files. This work was supported in part by the Defense Advanced Research Projects Agency under contracts N00039-84-C-0211 and N00039-86-K-0431, by National Science Foundation grant DCR-83-52048, and by Digital Equipment Corporation, Bell-Northern Research and AT&amp;T Information Systems.
Exosomes, your body’s answer to immune health (2017)

Mesenchymal stromal cells (MSC) have a profound effect on the regulation of the immune system. MSCs show low expression of major histocompatibility complex (MHC)-II and costimulatory surface molecules that include CD40, CD40L, CD80 and CD86, indicating immunomodulatory properties (1). Interestingly, prior research indicated that MSCs are important immune modulators that exert their biological effects in a paracrine manner, involving secretion of exosomes. Exosomes have emerged as an important means for cellular communication through the transfer of proteins and genetic material between cells. Exosomes are a form of extracellular lipid vesicle that are usually 40–100 nm in diameter, have a density of 1.10–1.18 g/mL on sucrose gradients and contain exosome membrane-specific proteins such as CD9, CD63 and CD81 (2).
Endometrial CXCL13 Expression Is Cycle Regulated in Humans and Aberrantly Expressed in Humans and Rhesus Macaques With Endometriosis (2020)

C-X-C ligand 13 (CXCL13), a regulator of mucosal immunity, is secreted by human endometrial epithelium and may be involved in embryo implantation. However, cyclic expression of human endometrial CXCL13 in health and disease is not well studied. This study examines cycle stage-specific endometrial CXCL13 expression in normal humans when compared to those with biopsy-confirmed, stage 1 to 4 endometriosis using real-time reverse transcriptase, real-time polymerase chain reaction and immunohistochemistry. Eutopic endometrial CXCL13 expression was also compared between normal, control Rhesus macaques, and macaques with advanced endometriosis. In healthy women, CXLC13 messenger RNA expression was minimal in the proliferative phase and maximal in the secretory phase. However, in the presence of endometriosis, proliferative-phase endometrial expression markedly increased in both humans and rhesus subjects (P < .05). The cross-species and cross-stage concordance suggests a pathophysiologic role for CXCL13 in endometriosis and its use as a biomarker for disease.