gebhart/patrepeval huggingface dataset:
Synthesis of polyamides and polyureas containing leucine-tyrosine linkages (1997)

Monomers with leucine–tyrosine linkages were synthesized using diphenyl phosphoryl azide as a coupling reagent. Leucyltyrosylpoly(propylene glycol) bis(2-aminopropyl ether) tyrosylleucine (monomer 1) has a longer spacer: poly(propylene glycol) bis(2-aminopropyl ether) (Jeffamine® D-400), and leucyltyrosyliminohexamethyleneiminotyrosylleucine (monomer 2) has a shorter spacer: hexamethylenediamine. Polyureas from monomers 1 and 2 with hexamethylene diisocyanate and methylenedi-p-phenyl diisocyanate were synthesized. Polyamide, polyesteramide from monomer 2 were synthesized. The characterization of these polymers using 1H-NMR, 13C-NMR, solid-state 13C-NMR, IR, GPC, and also thermal analysis are presented. © 1997 John Wiley & Sons, Inc.
Vertical GaN p+-n junction diode with ideal avalanche capability grown by halide vapor phase epitaxy (2021)

A vertical GaN p+-n junction diode with an ideal breakdown voltage was grown by halide vapor phase epitaxy (HVPE). A steep p+-n interface was observed even with the use of the HVPE method. No Si-accumulating layer was formed at the p+-n interface because of the continuous HVPE growth from the n-type drift layer to the p-type layer. This method provides improved electrical properties compared with the regrowth of p-type GaN layers. The minimum ideality factor of approximately 1.6 was obtained. The breakdown voltage increased from 874 to 974 V with the increase in the temperature from 25 to 200 °C, which suggests that avalanche multiplication causes the breakdown. The temperature-dependent breakdown voltage was in good agreement with the breakdown voltage calculated using the ideal critical electric field. These results indicate that HVPE is promising for the fabrication of vertical GaN power devices.
Estimating advertisability of tail queries for sponsored search (2010)

Sponsored search is one of the major sources of revenue for search engines on the World Wide Web. It has been observed that while showing ads for every query maximizes short-term revenue, irrelevant ads lead to poor user experience and less revenue in the long-term. Hence, it is in search engines' interest to place ads only for queries that are likely to attract ad-clicks. Many algorithms for estimating query advertisability exist in literature, but most of these methods have been proposed for and tested on the frequent or "head" queries. Since query frequencies on search engine are known to be distributed as a power-law, this leaves a huge fraction of the queries uncovered.
Design of highly efficient, high output power, L-band class D<sup>-1</sup> RF power amplifiers using GaN MESFET devices. (2007)

In this article, two class D <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> amplifiers is presented, both implemented with GaN MESFETs and working around 900 MHz, delivering 20.7/51.1 W output power with 75/78% peak drain-efficiency. A simple nonlinear model optimized for switched mode operation is developed from basic device data, and is used to predict intrinsic current and voltage waveforms during the design process. In general, very good agreement between modeled and simulated data is obtained considering the limited amount of parasitic parameters covered by the device model.
Overview Pulmonary-Allergy, Dermatological, Gastrointestinal & Arthritis Recent advances in leukotriene B4 receptor antagonist research (1996)

Leukotriene B4 (LTB4), a product of the arachidonic acid cascade, has been shown to be an important modulator of inflammatory cell function, the overproduction of which is believed to potentiate the tissue damage seen in many inflammatory diseases where medical needs remain unmet. Several antagonists of the LTB4 receptor are poised for clinical trial and a new spate of third generation compounds has been revealed in the recent patent literature.
Effect of raw milk on allergic responses in a murine model of gastrointestinal allergy (2014)

Epidemiological studies have shown an association between the consumption of raw farm milk and reduced incidence of allergy. In the present study, we fed untreated raw milk, gamma-sterilised milk, heat-treated milk or water to mice and compared their responses to allergen exposure and challenge treatment in a mouse model of gastrointestinal allergy. From weaning (3 weeks old), groups of BALB/c female mice (n 8) received raw milk, gamma-sterilised milk, heated milk or water via drink bottles, with the control group receiving water. All mice were fed a standard (dairy protein-free) rodent diet. At 6 and 8 weeks, groups were given intra-peritoneal injections with ovalbumin (OVA)/alum to sensitise them to the antigen. Controls were sham immunised. At week 10, mice were fasted and challenged four times on alternate days by intra-gastric administration with 50 mg OVA or saline. Levels of bacteria and milk proteins were assessed in milk samples. Mouse serum levels of specific IgE, IgG1 and IgG2a antibodies and mouse mast cell protease-1 (MMCP-1) were determined. Cytokine responses to 48 h activation with OVA were measured in cultured splenocytes from mice. Sterilised and heated milks contained no viable bacteria and reduced detectable levels of many milk proteins, in contrast to raw milk. Mice drinking raw milk had highest serum MMCP-1 and specific-OVA IgE responses. Cultured splenocytes from OVA-primed mice produced similar levels of IL-4 in response to the antigen; however, IL-10 levels were highest from mice drinking raw milk. Overall, the present study adds to the evidence that consuming different types of milk can affect allergic responses to a non-related dietary antigen.
Isothermal vapor-liquid equilibrium of binary mixtures containing pyrrolidine (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsothermal vapor-liquid equilibrium of binary mixtures containing pyrrolidineHuey S. Wu, William E. Locke III, and Stanley I. SandlerCite this: J. Chem. Eng. Data 1990, 35, 2, 169–172Publication Date (Print):April 1, 1990Publication History Published online1 May 2002Published inissue 1 April 1990https://pubs.acs.org/doi/10.1021/je00060a021https://doi.org/10.1021/je00060a021research-articleACS PublicationsRequest reuse permissionsArticle Views281Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Variable-Stiffness–Mode Dielectric Elastomer Devices (2008)

Dielectric elastomers, or more precisely dielectric polymers, are a relatively new class of materials for variable-stiffness and variable-damping devices. Dielectric elastomers offer significant potential advantages compared with previous variable stiffness smart materials. Advantages include simplicity, broad dynamic range, ability to reach zero stiffness, low cost, minimal mass, shock tolerance, simple drive circuitry, and design flexibility. Dielectric elastomer devices in the variable-stiffness mode convert electrical and mechanical energy back and forth to change mechanical impedance. This type of electromechanical transduction distinguishes the variable stiffness mode from simply using a dielectric elastomer actuator to alter the geometry, and hence the stiffness, of the device. Stiffness using a variable-stiffness mode depends heavily on the electrical loading of the dielectric elastomer. Analysis shows that a constant voltage loading reduces stiffness, down to zero in some cases, while a constant charge loading increases stiffness. Many applications can be considered for dielectric elastomer variable-stiffness mode such as vibration control, suspensions, and tuning consumer devices for user comfort or preference. As with dielectric elastomer actuators and generators, silicones and acrylics are the most promising materials for variable-stiffness-mode devices.
The effect of dietary resistant starch type 2 on the microbiota and markers of gut inflammation in rural Malawi children (2015)

Our findings do not support the hypothesis that RS reduces gut inflammation in rural Malawian children.
Spectroscopy and Electrochemistry of Cytochrome P450 BM3-Surfactant Film Assemblies (2006)

We report analyses of electrochemical and spectroscopic measurements on cytochrome P450 BM3 (BM3) in didodecyldimethylammonium bromide (DDAB) surfactant films. Electronic absorption spectra of BM3-DDAB films on silica slides reveal the characteristic low-spin FeIII heme absorption maximum at 418 nm. A prominent peak in the absorption spectrum of BM3 FeII-CO in a DDAB dispersion is at 448 nm; in spectra of aged samples, a shoulder at approximately 420 nm is present. Infrared absorption spectra of the BM3 FeII-CO complex in DDAB dispersions feature a time-dependent shift of the carbonyl stretching frequency from 1950 to 2080 cm(-1). Voltammetry of BM3-DDAB films on graphite electrodes gave the following results: FeIII/II E(1/2) at -260 mV (vs SCE), approximately 300 mV positive of the value measured in solution; DeltaS degrees (rc), DeltaS degrees , and DeltaH degrees values for water-ligated BM3 in DDAB are -98 J mol(-1) K(-1), -163 J mol(-1) K(-1), and -47 kJ mol(-1), respectively; values for the imidazole-ligated enzyme are -8 J mol(-1) K(-1), -73 J mol(-1) K(-1), and -21 kJ mol(-1). Taken together, the data suggest that BM3 adopts a compact conformation within DDAB that in turn strengthens hydrogen bonding interactions with the heme axial cysteine, producing a P420-like species with decreased electron density around the metal center.
Loss and Delay Accountability for the Internet (2007)

The Internet provides no information on the fate of transmitted packets, and end systems cannot determine who is responsible for dropping or delaying their traffic. As a result, they cannot verify that their ISPs are honoring their service level agreements, nor can they react to adverse network conditions appropriately. While current probing tools provide some assistance in this regard, they only give feedback on probes, not actual traffic. Moreover, service providers could, at any time, render their network opaque to such tools. We propose Audit, an explicit accountability interface, through which ISPs can pro-actively supply feedback to traffic sources on loss and delay, at administrative-domain granularity. Notably, our interface is resistant to ISP lies and can be implemented with a modest NetFlow modification. On our Click-based prototype, playback of real traces from a Tier-1 ISP reveals less than 2% bandwidth overhead. Finally, our proposal benefits not only end systems, but also ISPs, who can now control the amount and quality of information revealed about their internals.
Cross-Dimensional Gestural Interaction Techniques for Hybrid Imrnersive Environments (2006)

We present a set of cross-dimensional interaction techniques for a hybrid user interface that integrates existing 2D and 3D visualization and interaction devices. Our approach is built around one-and two-handed gestures that support the seamless transition of data between co-located 2D and 3D contexts. Our testbed environment combines a 2D multi-user, multi-touch, projection surface with 3D head-tracked, see-through, head-worn displays and 3D tracked gloves to form a multi-display augmented reality. We address some of the ways in which we can interact with private data in a collaborative, heterogeneous workspace. We also report on a pilot usability study to evaluate the effectiveness and ease of use of the cross-dimensional interactions.
Rapid and Sensitive Detection of Brain-Derived Neurotrophic Factor with a Plasmonic Chip (2013)

Plasmonic chips, which are grating replicas coated with thin metal layers and overlayers such as ZnO, were applied in immunosensors to improve their detection sensitivity. Fluorescence from labeled antibodies bound to plasmonic chips can be enhanced on the basis of a grating-coupled surface plasmon resonance (GC-SPR) field. In this study, as one of the representative candidate protein markers for brain disorders, the brain-derived neurotrophic factor (BDNF) was quantitatively measured by sandwich assay on a plasmonic chip and detected on our plasmonic chip in the concentration of 5–7 ng/mL within 40 min. Furthermore, BDNF was detected in the blood sera from three types of mice: wild-type mice and two types of mutant mice. This technique is promising as a new clinical diagnosis tool for brain disorders based on scientific evidence such as blood test results.
Pilot study of the efficacy and safety of lettuce seed oil in patients with sleep disorders (2011)

L. sativa seed oil was found to be a useful sleeping aid and may be a hazard-free line of treatment, especially in geriatric patients suffering from mild-to-moderate forms of anxiety and sleeping difficulties.
Sex hormone modulation of flow velocity in the parametrial artery of the pregnant rat (1995)

The objective of the study was to correlate the disparate distal/proximal state of maturation of uterine segments in the rat with the hemodynamics of the parametrial uterine artery. Flow velocity was determined by the methylene blue photometric analysis. In nonpregnant animals, the velocity in the distal (VD-->P) and proximal (VP-->D) portions of the parametrial artery were similar, but in late pregnancy, VD-->P was higher than VP-->D. The difference was associated with an increased width of the distal part of the parametrial artery. In addition, the distance from the proximal end of the parametrial artery where the D-->P and P-->D streams collided decreased in animals in late pregnancy, compared with nonpregnant animals. Treatment with estradiol and RU-486 reversed the pregnancy-related hemodynamic changes. The pregnancy-related shift in flow velocity in the parametrial artery is crucial to rat fetal survival in utero and may be a mechanism in vivo for promoting maturation of distal, compared with proximal, segments of the uterine horn.
Follicle-stimulating hormone receptor is expressed in human ovarian surface epithelium and fallopian tube. (1996)

The cellular expression of pituitary gonadotropin receptors in gonadal tissues is poorly defined because of the lack of suitable reagents. In this study, we developed in situ hybridization and reverse transcription polymerase chain reaction techniques for the evaluation of follicle-stimulating hormone receptor (FSHR) expression in the ovary and fallopian tube. Using a single-strand RNA probe, we demonstrated that FSHR mRNA expression is strongest in Graafian follicles. Within these developing follicles, granulosa cells showed the greatest expression, although both theca interna and theca externa were also positive, interna greater than externa. Granulosa cells in both primary and primordial follicles were positive, with primordial follicles showing only weak focal positivity. Ovarian surface epithelium and fallopian tube epithelium, not previously recognized to express FSHR, were both strongly positive. The FSHR expression in the ovary and fallopian tube was confirmed by reverse transcription polymerase chain reaction. Our results indicated that the FSHR is expressed in a cell-specific fashion at different stages of follicular development and is also expressed in ovarian surface and fallopian tube epithelia. The presence of FSHR in ovarian surface epithelium and of gonadotropin-binding sites in ovarian neoplasms provide additional evidence supporting the derivation of epithelial ovarian tumors from the surface epithelium and should promote heightened interest in the gonadotropin theory of ovarian tumorigenesis. More importantly, this study shows the feasibility of evaluating FSHR expression by both in situ hybridization and reverse transcription polymerase chain reaction. Application of these techniques to tumor specimens will help to elucidate the role of gonadotropins and their receptors in the carcinogenesis of gynecological tumors.
Soft crystal martensites: An in situ resonant soft x-ray scattering study of a liquid crystal martensitic transformation (2020)

Liquid crystal blue phases (BPs) are three-dimensional soft crystals with unit cell sizes orders of magnitude larger than those of classic, atomic crystals. The directed self-assembly of BPs on chemically patterned surfaces uniquely enables detailed in situ resonant soft x-ray scattering measurements of martensitic phase transformations in these systems. The formation of twin lamellae is explicitly identified during the BPII-to-BPI transformation, further corroborating the martensitic nature of this transformation and broadening the analogy between soft and atomic crystal diffusionless phase transformations to include their strain-release mechanisms.
Macrocyclization by Nickel‐Catalyzed, Ester‐Promoted, Epoxide–Alkyne Reductive Coupling: Total Synthesis of (−)‐Gloeosporone (2009)

Abstract Im Zentrum der Totalsynthese der Titelverbindung steht eine neuartige Strategie, bei der mithilfe von Triethylboran und einem Nickel(0)‐Phosphan‐Komplex effizient ein 14‐gliedriger Ring geschlossen wird (siehe Schema; cod=Cyclooctadien). Die Synthese verläuft über zehn Stufen in ca. 9 % Gesamtausbeute. magnified image
Mullite ceramic substrate for thin-film application (2002)

The advantages of mullite ceramic for thin-film application are examined. Using homogeneous powder, a dense mullite substrate consisting of fine mullite grains was provided without the addition of a sintering aid. The properties obtained are superior to those of the mullite presented by M. Horiuchi et al. (1988) and a conventional alumina for application to packages and substrates: low dielectric constant
Supplementary Data from Phase I Clinical Trial of Selinexor in Combination with Daunorubicin and Cytarabine in Previously Untreated Poor-Risk Acute Myeloid Leukemia (2023)

&lt;p&gt;Supplementary Methods.&lt;/p&gt;
Opening Remarks from Conference Chairs (2020)

Welcome to the Plasmonics: Design, Materials, Fabrication, Characterization, and Applications XVIII conference
The Role of Radical Prostatectomy in High-Risk Localized, Node-Positive and Metastatic Prostate Cancer (2016)

A lack of quality evidence comparing management strategies confounds complex treatment decisions for patients with high-risk prostate cancers. No randomized trial comparing surgery to radiation has been successfully completed. Despite inherent selection biases, however, observational and registry data suggest improved outcomes for patients initially managed with prostatectomy. As consensus shifts away from aggressive treatment for low-risk disease and toward multimodal treatment of locally advanced and metastatic disease, there is renewed interest in surgery for local control in patients presenting with high-risk localized, node-positive and minimally metastatic disease. The objective of this review is to examine the evidence evaluating clinical outcomes of patients with high-risk clinically localized, node-positive and metastatic prostate cancer treated with radical prostatectomy.
PCR detection of the TaqA RFLP at the DRD2 locus (1993)

Journal Article PCR detection of the TaqA RFLP at the DRD2 locus Get access D.K. Grandy, D.K. Grandy * 1Departments of Cell Biology and Departments of Anatomy, Oregon Health Sciences UniversityPortland, OR 97201, USA2Vollum Institute, Oregon Health Sciences UniversityPortland, OR 97201, USA *To whom correspondence should be addressed Search for other works by this author on: Oxford Academic PubMed Google Scholar Y. Zhang, Y. Zhang 1Departments of Cell Biology and Departments of Anatomy, Oregon Health Sciences UniversityPortland, OR 97201, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar O. Civelli O. Civelli 1Departments of Cell Biology and Departments of Anatomy, Oregon Health Sciences UniversityPortland, OR 97201, USA3F Hoffmann-LaRoche, IncBasel, Switzerland Search for other works by this author on: Oxford Academic PubMed Google Scholar Human Molecular Genetics, Volume 2, Issue 12, December 1993, Page 2197, https://doi.org/10.1093/hmg/2.12.2197-a Published: 01 December 1993
Machine-Learning-Assisted Topology Optimization for Refractory Photonics (2019)

We expand a conventional metasurface design methodology to a global optimization space by advancing topology optimization via artificial-intelligence-assisted algorithms and tailorable materials platforms. We apply the developed approach to design efficient refractory photonics for thermophotovoltaics.
High-Velocity Metal Forming (2006)

Abstract This article emphasizes the traits that are common to high-velocity forming operations. It describes general principles on how metal forming is accomplished and analyzed when inertial forces are large. The article discusses the principal methods of high-velocity forming, such as explosive forming, electrohydraulic forming, and electromagnetic forming. It provides examples that illustrate how these methods can be practically applied. The article concludes with information on the status and development potential for the technology.
Development of 38GHz-band wireless communication system using high altitude platform station (HAPS) for 5G network -- study on effective frequency resources utilization with polarization -- (2021)

HAPS (High-Altitude Platform Station) is expected to extend the communication coverage in the era of beyond 5G. HAPS moves around a circle at 20km altitude and tries to make beams fixed on the earth by beamforming. However, if HAPS uses polarization like satellite communication, there is a possibility that received SNR (Signal to Noise power Ratio) degrades because the fluctuation of HAPS aircraft could generate polarization mismatch between HAPS and earth stations. This paper reports experimental results using on-air polarization signal from a satellite with artificial polarization offset to evaluate feasibility of polarization utilization in HAPS. The results show SNR loss due to the polarization offset can be confined within 0.5dB and good tracking performance thanks to the polarization diversity by MMSE (Minimum Mean Square Error) receiver.
DG-LoRa: Deterministic Group Acknowledgment Transmissions in LoRa Networks for Industrial IoT Applications (2021)

In this paper, we propose a novel MAC protocol, called DG-LoRa, for improving scalability in low power wide area networks. DG-LoRa is backward compatible with legacy LoRaWAN and adds new features, such as group acknowledgment transmissions in the time-synchronized frame structure that supports determinism on channel access. In DG-LoRa, the number of responses to data frames that are transmitted from end devices is maximized by allocating the spreading factor and timeslot in the frame structure. We evaluate the performance of DG-LoRa using the Monte-Carlo simulation and then compare it with the performance of legacy LoRaWAN in terms of data drop rate and the number of retransmissions. Our numerical results show that DG-LoRa supports approximately five times more connections to the LoRa network satisfying a 5% data drop rate. Also, it is observed that DG-LoRa enables low overhead by reducing the number of data frame retransmissions.