gebhart/patrepeval huggingface dataset:
Template‐Free, Low‐Temperature Synthesis of Crystalline Barium Titanate Nanoparticles under Bio‐Inspired Conditions (2006)

Schwämme nachgeahmt: Gut definierte kristalline Nanopartikel von kubischem BaTiO3 werden bei sehr niedriger Temperatur mit einem durch die Natur inspirierten Verfahren erhalten. Ein Dimetallalkoxid dient als alleinige Vorstufe in einer Dampfdiffusions-Sol-Gel-Synthese. Wasser und der Katalysator (HCl) werden mit einem räumlichen und zeitlichen Gradienten zur Verfügung gestellt, um das langsame Wachsen der Nanopartikel zu unterstützen. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2006/z602571_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Toward a molecular genetic analysis of spermatogenesis in Drosophila melanogaster: characterization of male-sterile mutants generated by single P element mutagenesis. (1993)

We describe 83 recessive autosomal male-sterile mutations, generated by single P element mutagenesis in Drosophila melanogaster. Each mutation has been localized to a lettered subdivision of the polytene map. Reversion analyses, as well as complementation tests using available chromosomal deficiencies, indicate that the insertions are responsible for the mutant phenotypes. These mutations represent 63 complementation groups, 58 of which are required for spermatogenesis. Phenotypes of the spermatogenesis mutants were analyzed by light microscopy. Mutations in 12 loci affect germline proliferation, spermatocyte growth, or meiosis. Mutations in 46 other loci disrupt differentiation and maturation of spermatids into motile sperm. This collection of male-sterile mutants provides the basis for a molecular genetic analysis of spermatogenesis.
Synthesis and electrochemical studies of a covalently linked cobalt(ii) phthalocyanine–cobalt(ii) porphyrin conjugate (2005)

The synthesis of a cobalt phthalocyanine–cobalt porphyrin heteropentamer (cobalt(II) phthalocyanine–tetrakis(cobalt(II) tetrakis(5-phenoxy-10,15,20-triphenylporphyrin))), (CoPc–(CoTPP)4), containing four units of cobalt tetraphenylporphyrin linked to a central cobalt phthalocyanine macrocycle via ether linkages is reported. Cyclic voltammetry and spectroelectrochemistry were employed to characterize the complexes. Cyclic voltammetry and square wave voltammetry revealed nine processes. Spectroelectrochemistry of the pentamer confirmed that reduction occurs on the individual components in an alternating manner; the first reduction occurring on the CoTPP moieties, the second on the CoPc moiety, the third on the CoTPP moieties and so on. Oxidation occurred first on the CoPc moiety of the pentamer.
Supplementary Table 3 from Characterization of an Oxaliplatin Sensitivity Predictor in a Preclinical Murine Model of Colorectal Cancer (2023)

&lt;p&gt;PDF file - 39K, Tumor growth inhibition of patient derived colorectal cancer explant to oxaliplatin.&lt;/p&gt;
Inter-laboratory validation of the measurement of follicle stimulating hormone (FSH) after various lengths of frozen storage (2010)

The findings suggest that degradation of serum samples stored between 11 months and 2-3 years at -25 degrees C can lead to unstable FSH measurements. Inter-laboratory variability due to frozen storage time and manufacturer differences in assay results should be accounted for when designing and implementing research or clinical quality control activities involving serum FSH at multiple study sites.
B-Type Natriuretic Peptide in the Critically Ill with Acute Kidney Injury (2011)

Introduction. Acute kidney injury (AKI) is common in the intensive care unit (ICU) and associated with poor outcome. Plasma B-type natriuretic peptide (BNP) is a biomarker related to myocardial overload, and is elevated in some ICU patients. There is a high prevalence of both cardiac and renal dysfunction in ICU patients. Aims. To investigate whether plasma BNP levels in the first 48 hours were associated with AKI in ICU patients. Methods. We studied a cohort of 34 consecutive ICU patients. Primary outcome was presence of AKI on presentation, or during ICU stay. Results. For patients with AKI on presentation, BNP was statistically higher at 24 and 48 hours than No-AKI patients (865 versus 148 pg/mL; 1380 versus 131 pg/mL). For patients developing AKI during 48 hours, BNP was statistically higher at 0, 24 and 48 hours than No-AKI patients (510 versus 197 pg/mL; 552 versus 124 pg/mL; 949 versus 104 pg/mL). Conclusion. Critically ill patients with AKI on presentation or during ICU stay have higher levels of the cardiac biomarker BNP relative to No-AKI patients. Elevated levels of plasma BNP may help identify patients with elevated risk of AKI in the ICU setting. The mechanism for this cardiorenal connection requires further investigation.
Real-Time Detection and Capture of Invasive Cell Subpopulations from Co-Cultures (2022)

Invasion and metastatic spread of cancer cells are the major cause of death from cancer. Assays developed early on to measure the invasive potential of cancer cell populations typically generate a single endpoint measurement that does not distinguish between cancer cell subpopulations with different invasive potential. Also, the tumor microenvironment consists of different resident stromal and immune cells that alter and participate in the invasive behavior of cancer cells. Invasion into tissues also plays a role in immune cell subpopulations fending off microorganisms or eliminating diseased cells from the parenchyma and endothelial cells during tissue remodeling and angiogenesis. Real-Time Cellular Analysis (RTCA) that utilizes impedance biosensors to monitor cell invasion was a major step forward beyond endpoint measurement of invasion: this provides continuous measurements over time and thus can reveal differences in invasion rates that are lost in the endpoint assay. Using current RTCA technology, we expanded dual-chamber arrays by adding a further chamber that can contain stromal and/or immune cells and allows measuring the rate of invasion under the influence of secreted factors from co-cultured stromal or immune cells over time. Beyond this, the unique design allows for detaching chambers at any time and isolating of the most invasive cancer cell, or other cell subpopulations that are present in heterogeneous mixes of tumor isolates tested. These most invasive cancer cells and other cell subpopulations drive malignant progression to metastatic disease, and their molecular characteristics are important for in-depth mechanistic studies, the development of diagnostic probes for their detection, and the assessment of vulnerabilities. Thus, the inclusion of small- or large-molecule drugs can be used to test the potential of therapies that target cancer and/or stromal cell subpopulations with the goal of inhibiting (e.g., cancer cells) or enhancing (e.g., immune cells) invasive behavior.
Statistical channel model for 60 GHz WLAN systems in conference room environment (2010)

In this work, a methodology of statistical channel modeling for 60 GHz WLAN systems is proposed and a channel model for the office conference room environment is developed. The proposed methodology takes into account the most important properties of the indoor 60 GHz propagation channel such as large propagation loss and necessity to use steerable directional antennas by the WLAN stations, quasi-optical propagation nature, clustering structure of the channel, and significant impact of the polarization characteristics. A general mathematical structure of the channel model that supports all the described 60 GHz propagation channel properties is suggested. Then the conference room scenario for 60 GHz WLAN systems is introduced. Development of the inter cluster, intra cluster, and polarization impact modeling parameters is considered in details first explaining the used methodology for each channel modeling aspect and then followed by its application to the conference room scenario. The raw data for the channel model development include the experimental results [1], [2] and ray-tracing simulations for the conference room scenario. The proposed channel modeling methodology and the developed conference room channel model were adopted by the IEEE 802.11ad committee for 60 GHz WLAN systems standardization.
ANALYTIC FORMULATION FOR 3D DIFFUSION TENSOR (2008)

This work deals with image processing based upon non-linear diffusion PDEs (Partial Differential Equations). Some analytic formulation will be introduced to obtain the 3D diffusion tensor, replacing Jacobi´s numerical methods by expressions based on invariants of the symmetric matrix. Later, CED (Coherence Enhancing Filtering) anisotropic filtering properties will be observed and will be combined with isotropic diffusion, providing a type of filtering that allows combining noise removal and local structure preservation. Last, some applications 3D grey-level will be presented.
Explorations in Early Southeast Asian History (1976)

While following the probes of foreign individuals into various obscure parts of Southeast Asia over the centuries is a diverting and entertaining pastime, the purpose of this volume is to investigate this past with the mind, to question and postulate upon the historical patterns that have developed from earlier study of the area, and to bring concepts from other areas and disciplines to bear on the existing information. The product of this effort, as it is encompassed in this volume, is not an attempt at the definitive study of any of the topics. It is rather a series of speculations on the directions feasible for the further study of the Southeast Asian past. As such, the answers proposed in these essays are really questions. Are the ideas presented here true within the specific historical contexts for which they have been developed? If so, can we use these ideas, or variations of them, to interpret the history of other parts of Southeast Asia? If not, what other ideas may be brought to bear on these situations in order to understand them? The ultimate aim of this volume is thus a challenge to the profession at large not only to criticize what we have done, but also to go beyond our postulations and create new ones. [xi]
Supplementary Tables 1-3 from Cellular Mechanisms Underlying Complete Hematological Response of Chronic Myeloid Leukemia to BRAF and MEK1/2 Inhibition in a Patient with Concomitant Metastatic Melanoma (2023)

&lt;p&gt;Supplementary Tables 1-3. Supplementary Table 1: Changes in manual differential white cell counts over time under treatment with BRAF/MEK inhibitor combination therapy for melanoma. Supplementary Table 2. BCR-ABL monitoring during treatment. Supplementary Table 3. Leukocyte sub-populations as defined by flow cytometry.&lt;/p&gt;
ChemInform Abstract: Synthesis and Biological Evaluation of Fully Synthetic Bryostatin Analogues. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Surface Modification of T-Lymphocytes Observed during Rosetting (1974)

Scanning electron microscopy has been used to characterize alterations of lymphocyte surface topology that occur on contact with erythrocytes during the rosetting reaction. Molt-4 cells, a line of leukemic human lymphocytes, defined as T-cells through their ability to form rosettes with sheep erythrocytes, were used for this. Unreacted Molt-4 cells exhibit surfaces that are virtually smooth and carry few microvilli. In contrast, Molt-4 cells in rosettes display a time-dependent modification of surface topology, characterized by the emergence of numerous, long microvilli, particularly in areas of red cell contact.
Speckle-free rear-projection screen using two close screens in slow relative motion (1976)

Speckle in rear-projection screens, such as those used in microfiche viewers, reduces resolution and can cause viewer fatigue. Many speckle-reduction techniques have been tried with varying degrees of success, including rapid movement of a single screen in its plane, the use of two stationary spaced screens, liquid-crystal screens, and the use of two closely spaced screens in slow relative orbital motion. We describe a simplified, two-screen support that permits only linear screen motion, and show that such motion provides total speckle elimination. An analysis of speckle in such screens is presented which accounts for the observed remarkable sensitivity of the speckle pattern to minute screen displacements. To confirm this analysis we have measured the speckle pattern’s correlation as a function of screen displacement using the speckle interferometry method of Françon. We consider the effects of a spatially and spectrally extended incandescent light source, and conclude that these effects are negligible in our application compared to the effect of screen motion. We show that these three speckle-reducing effects (screen motion, spatial extent of the source, and spectral extent of the source) can be considered together by introducing the notion of space-time correlation cells.
Data from Cancer Induces a Stress Ileopathy Depending on β-Adrenergic Receptors and Promoting Dysbiosis that Contributes to Carcinogenesis (2023)

&lt;div&gt;Abstract&lt;p&gt;Gut dysbiosis has been associated with intestinal and extraintestinal malignancies, but whether and how carcinogenesis drives compositional shifts of the microbiome to its own benefit remains an open conundrum. Here, we show that malignant processes can cause ileal mucosa atrophy, with villous microvascular constriction associated with dominance of sympathetic over cholinergic signaling. The rapid onset of tumorigenesis induced a burst of REG3γ release by ileal cells, and transient epithelial barrier permeability that culminated in overt and long-lasting dysbiosis dominated by Gram-positive &lt;i&gt;Clostridium&lt;/i&gt; species. Pharmacologic blockade of β-adrenergic receptors or genetic deficiency in &lt;i&gt;Adrb2&lt;/i&gt; gene, vancomycin, or cohousing of tumor bearers with tumor-free littermates prevented cancer-induced ileopathy, eventually slowing tumor growth kinetics. Patients with cancer harbor distinct hallmarks of this stress ileopathy dominated by &lt;i&gt;Clostridium&lt;/i&gt; species. Hence, stress ileopathy is a corollary disease of extraintestinal malignancies requiring specific therapies.&lt;/p&gt;Significance:&lt;p&gt;Whether gut dysbiosis promotes tumorigenesis and how it controls tumor progression remain open questions. We show that 50% of transplantable extraintestinal malignancies triggered a β-adrenergic receptor–dependent ileal mucosa atrophy, associated with increased gut permeability, sustained &lt;i&gt;Clostridium&lt;/i&gt; spp.–related dysbiosis, and cancer growth. Vancomycin or propranolol prevented cancer-associated stress ileopathy.&lt;/p&gt;&lt;p&gt;&lt;i&gt;This article is highlighted in the In This Issue feature, p. 873&lt;/i&gt;&lt;/p&gt;&lt;/div&gt;
Current practice in transvenous lead extraction: a European Heart Rhythm Association EP Network Survey (2012)

This survey gives an interesting snapshot of lead extraction in Europe today and gives some clues for future research and prospective European registries.
Water dynamics : 5th International Workshop on Water Dynamics, Sendai, Japan, 25-27 September 2007 (2008)

Water is the essential constituent for life and this proceedings covers the role of water in materials, earth science and geo/biosphere. It assesses the role of water in a range of earth processes and considers environmentally friendly approaches to preserving water environments for present and future generations. Included are transport phenomena and chemical reactivity, origin of geofluids, fluid-rock interactions, water as a trigger for earthquake and volcanic eruptions, and the global circulation of water in the Earth's interior (crust, mantle and core), as well as the cause-and effect relationship between water, ecology and life in various environments.
Power efficient structure for conversion between arbitrary sampling rates (2004)

This work presents a novel efficient method for conversion between arbitrary sampling rates. The method allows arbitrary number of zeros at multiples of both input and output sampling rates, thus it has both good anti-imaging and good anti-aliasing properties. Further, two equivalent efficient implementation structures are presented. The implementation is done either by using the modified Farrow or transposed modified Farrow structure. By choosing one of these two alternatives appropriately, it is possible to shift most of the operations to lower sampling rate.
Full integration of extremely large time constants in CMOS (1991)

A method for implementing large time constants in a CMOS technology is presented. The method uses a modified operational transconductance amplifier (OTA) to obtain electronic multiplication of the time constant. Much attention is paid to offset-voltage reduction and area minimisation.
411: Defining Prostate Cancer Progression by Molecular Profiling of Laser Capture Micro Dissected Prostate Tissues (2006)

You have accessJournal of UrologyDiscussed Poster, Sunday, May 21, 2006, 1:00 - 4:00 pm1 Apr 2006411: Defining Prostate Cancer Progression by Molecular Profiling of Laser Capture Micro Dissected Prostate Tissues Rohit Mehra, Scott A. Tomlins, Daniel Rhodes, Xuhong Cao, Arul M. Chinnaiyan, and Rajal B. Shah Rohit MehraRohit Mehra More articles by this author , Scott A. TomlinsScott A. Tomlins More articles by this author , Daniel RhodesDaniel Rhodes More articles by this author , Xuhong CaoXuhong Cao More articles by this author , Arul M. ChinnaiyanArul M. Chinnaiyan More articles by this author , and Rajal B. ShahRajal B. Shah More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)32667-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "411: Defining Prostate Cancer Progression by Molecular Profiling of Laser Capture Micro Dissected Prostate Tissues." The Journal of Urology, 175(4S), p. 134 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 134 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Rohit Mehra More articles by this author Scott A. Tomlins More articles by this author Daniel Rhodes More articles by this author Xuhong Cao More articles by this author Arul M. Chinnaiyan More articles by this author Rajal B. Shah More articles by this author Expand All Advertisement PDF downloadLoading ...
Empirically derived abstractions in uncore power modeling for a server-class processor chip (2014)

Early-stage power modeling is an essential aspect of the process of defining efficient, yet high-performance microarchitectures. Pre-silicon power modeling has been an active area of research and development for well over a decade, although primarily focused on the processor cores. In this paper, we examine the challenge of developing practical abstractions in uncore power modeling in an industrial setting. We report a systematic methodology of abstractions in modeling with a focus on key uncore elements of the POWER8TM processor chip from IBM. The results show that the active power of these uncore elements can be modeled with acceptable levels of precision, by: (a) using just a few activity markers: e.g. reads, writes, retries and snoops; and (b) using a small set of systematically crafted microbenchmark stress test cases to measure the activity frequencies on a detailed, cycle- and latch-accurate RTL reference model.
Finite Element Human Body Model Thorax Response Validation With Matched Experimental Tests (2013)

Finite Element Models (FEMs) are increasingly used to evaluate occupant response and safety system effectiveness in automotive safety research.[1, 2] These models are validated against experimental tests with known results to evaluate the model’s ability to predict the occupant response. The FEM used for this study was the Total HUman Model for Safety (THUMS). The occupant thorax model has already been validated in three basic thorax loading conditions.[3] The hypothesis of this study was if the model had been successfully validated in these simplified configurations, additional loading conditions that involve a more complex load path should also follow the experimental response.
Pancreatic duct stones management. (1998)

One-dimensional models of the cardiovascular system can capture the physics of pulse waves but involve many parameters. Since these may vary among individuals, patient-specific models are difficult to construct. Sensitivity analysis can be used to rank model parameters by their effect on outputs and to quantify how uncertainty in parameters influences output uncertainty. This type of analysis is often conducted with a Monte Carlo method, where large numbers of model runs are used to assess input-output relations. The aim of this study was to demonstrate the computational efficiency of variance-based sensitivity analysis of 1D vascular models using Gaussian process emulators, compared to a standard Monte Carlo approach. The methodology was tested on four vascular networks of increasing complexity to analyse its scalability. The computational time needed to perform the sensitivity analysis with an emulator was reduced by the 99.96% compared to a Monte Carlo approach. Despite the reduced computational time, sensitivity indices obtained using the two approaches were comparable. The scalability study showed that the number of mechanistic simulations needed to train a Gaussian process for sensitivity analysis was of the order O(d), rather than O(d×103) needed for Monte Carlo analysis (where d is the number of parameters in the model). The efficiency of this approach, combined with capacity to estimate the impact of uncertain parameters on model outputs, will enable development of patient-specific models of the vascular system, and has the potential to produce results with clinical relevance.
Real-time composition control of InAlAs grown on InP using spectroscopic ellipsometry (2000)

Spectroscopic ellipsometry (SE) was shown to be an accurate in situ method for determining the composition and thickness of III–V semiconductor layers during growth. In order to fully exploit the potential of SE for real-time in situ control, one needs to acquire a database of optical constants. In this article, we present the acquisition and parameterization (both composition and temperature) of a fully dynamic database and its use in the real-time composition control of InAlAs grown on InP. This is accomplished by acquiring SE data from growing films of different compositions, while the temperature is controlled using feedback from band-gap thermometry. The layer compositions are assessed by fitting high-resolution x-ray diffraction patterns with a simulation based on dynamical diffraction theory. In order to improve the stability during real-time control, the database was parameterized using a transfer function model. The parameterized database was then used, in real time, during growth to control the InxAl1−xAs film composition (x) to within ±0.003.