gebhart/patrepeval huggingface dataset:
A New Ground Power Unit (GPU) Supply for Aircraft Applications (2018)

Nowadays, electrical energy is the alternative to supply aircraft systems. In this paper a new converter for ground power units supply in aircraft applications is proposed. The topology consists of a rectifier with an active current injection circuit linked to a three level neutral point clamped converter. The design procedure is detailed in this paper showing the principal requirements for the safe operation of the converter. Simulation results validate the satisfying performance of the proposed system.
The polytropic exponent of gas contained within air bubbles pulsating in a liquid (1983)

Gas bubbles that are driven into oscillation within a liquid pulsate with amplitudes that are determined largely by the thermodynamic behavior of the gas contained within the bubble. Theoretical approaches to the solution of the motion of the radius of the bubble normally involve the polytropic exponent of the gas. Measurements are presented of this exponent for three different gases and for a wide range of values of the exponent. Comparison with available theories indicates good agreeement between measurements and predictions provided the gas bubble is not driven near one of its harmonic resonances.
Phototherapy restores deficient type I interferon production and enhances antitumor responses in mycosis fungoides (2023)

Transcriptional profiling demonstrated markedly reduced type I IFN gene expression in untreated mycosis fungoides (MF) skin lesions compared with that in healthy skin. Type I IFN expression in MF correlated with antigen-presenting cell-associated IRF5 before psoralen plus UVA therapy and epithelial ULBP2 after therapy, suggesting an enhancement of epithelial type I IFN. Immunostains confirmed reduced baseline type I IFN production in MF and increased levels after psoralen plus UVA treatment in responding patients. Effective tumor clearance was associated with increased type I IFN expression, enhanced recruitment of CD8&amp;#43; T cells into skin lesions, and expression of genes associated with antigen-specific T-cell activation. IFNk, a keratinocyte-derived inducer of type I IFNs, was increased by psoralen plus UVA therapy and expression correlated with upregulation of other type I IFNs. In vitro, deletion of keratinocyte IFNk decreased baseline and UVA-induced expression of type I IFN and IFN response genes. In summary, we find a baseline deficit in type I IFN production in MF that is restored by psoralen plus UVA therapy and correlates with enhanced antitumor responses. This may explain why MF generally develops in sun-protected skin and suggests that drugs that increase epithelial type I IFNs, including topical MEK and EGFR inhibitors, may be effective therapies for MF.
MPI visualization and inductive heating of hybrid implant fibers (2019)

In this study, we evaluate the hyperthermia efficiency of polypropylene (PP) fibers with incorporated magnetic nanoparticles (MNP), which are used to develop inductive heatable stents in cancer therapy. Further, we investigate their depiction in magnetic particle imaging (MPI). We show that the intrinsic loss power (ILP) value depends on the MNP agglomeration state and their concentration inside the fibers, while the intensity values in the MPI images show a linear response with MNP concentration. We conclude that MNP dynamic magnetic behavior strongly changes with different MNP agglomeration states and magnetic field settings. Int. J. Mag. Part. Imag. 6(2), Suppl. 1, 2020, Article ID: 2009024, DOI: 10.18416/IJMPI.2020.2009024
Label-free DNA detection with a nanogap embedded complementary metal oxide semiconductor (2011)

A nanogap embedded complementary metal oxide semiconductor (NeCMOS) is demonstrated as a proof-of-concept for label-free detection of DNA sequence. When a partially carved nanogap between a gate and a silicon channel is filled with charged biomolecules, the gate dielectric constant and charges are changed. When the gate oxide thickness reduces, the threshold voltage is significantly affected by a change of the charges, whereas it is scarcely influenced by a change of the dielectric constant. In the case of DNA, those two factors act on the threshold voltage oppositely in an n-channel NeCMOS but collaboratively in a p-channel NeCMOS because of the negative charges of DNA. Hence, a p-channel NeCMOS with a thin gate oxide is more attractive for DNA detection because it enhances the shift of threshold voltage; that is, it improves the sensitivity of DNA detection. In addition, the shift of threshold voltage according to the nanogap length is also investigated and the longer nanogap shows more shift of the threshold voltage.
1552: Alpha-Methylacyl-COA Racemase (AMACR)-Based Molecular Imaging of Prostate Cancer (2006)

valuable tool avoid an unnecessary missing prostate cancer.
Remarkable Black‐Phase Robustness of CsPbI3 Nanocrystals Sealed in Solid SiO2/AlOx Sub‐Micron Particles (2021)

This work combines the high-temperature sintering method and atomic layer deposition (ALD) technique, and yields SiO<sub>2</sub> /AlO<sub>x</sub> -sealed γ-CsPbI<sub>3</sub> nanocrystals (NCs). The black-phase CsPbI<sub>3</sub> NCs, scattered and encapsulated firmly in solid SiO<sub>2</sub> sub-micron particles, maintain in black phases against water soaking, ultraviolet irradiation, and heating, exhibiting remarkable phase stability. A new phase-transition route, from γ via β to α phase without transferring into δ phase, has been discovered upon temperature increasing. The phase stability is ascribed to the high pressure exerted by the rigid SiO<sub>2</sub> encapsulations, and its condensed amorphous structures that prevent the permeation of H<sub>2</sub> O molecules. Nanoscale coating of Al<sub>2</sub> O<sub>3</sub> thin films, which are deposited on the surface of the CsPbI<sub>3</sub> -SiO<sub>2</sub> by ALD, enhances the protection against O<sub>2</sub> infiltration, greatly elevating the high-temperature stability of CsPbI<sub>3</sub> NCs sealed inside, as the samples remain bright after 1-h annealing in air at 400 °C. These fabrication and encapsulation techniques effectively prevent the formation of δ-CsPbI<sub>3</sub> under harsh environment, bringing the high-pressure preservation of black-phase CsPbI<sub>3</sub> from laboratory to industry toward potential applications in both photovoltaic and fluorescent areas.
IS-IS Extensions to Support Routing over IPv6 Dataplane (2019)

Segment Routing (SR) allows for a flexible definition of end-to-end
paths by encoding paths as sequences of topological sub-paths, called
segments. Segment routing architecture can be implemented over an
MPLS data plane as well as an IPv6 data plane. This draft describes
the IS-IS extensions required to support Segment Routing over an IPv6
data plane.
Kinetics of Electrophilic Fluorination of Steroids and Epimerisation of Fluorosteroids (2020)

Fluorinated steroids, which are synthesised by electrophilic fluorination, form a significant proportion of marketed pharmaceuticals. To gain quantitative information on fluorination at the 6-position of steroids, kinetics studies were conducted on enol ester derivatives of progesterone, testosterone, cholestenone and hydrocortisone with a series of electrophilic N-F reagents. The stereoselectivities of fluorination reactions of progesterone enol acetate and the kinetic effects of additives, including methanol and water, were investigated. The kinetics of epimerisation of 6β-fluoroprogesterone to the more pharmacologically active 6α-fluoroprogesterone isomer in HCl/acetic acid solutions are detailed.
ChemInform Abstract: Oxidation of Silyl Enol Ethers by Using IBX and IBX×N‐Oxide Complexes: A Mild and Selective Reaction for the Synthesis of Enones. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Incomplete and transitory decrease of glycolysis (2013)

During vessel sprouting, a migratory endothelial tip cell guides the sprout, while proliferating stalk cells elongate the branch. Tip and stalk cell phenotypes are not genetically predetermined fates, but are dynamically interchangeable to ensure that the fittest endothelial cell (EC) leads the vessel sprout. ECs increase glycolysis when forming new blood vessels. Genetic deficiency of the glycolytic activator PFKFB3 in ECs reduces vascular sprouting by impairing migration of tip cells and proliferation of stalk cells. PFKFB3-driven glycolysis promotes the tip cell phenotype during vessel sprouting, since PFKFB3 overexpression overrules the pro-stalk activity of Notch signaling. Furthermore, PFKFB3-deficient ECs cannot compete with wild-type neighbors to form new blood vessels in chimeric mosaic mice. In addition, pharmacological PFKFB3 blockade reduces pathological angiogenesis with modest systemic effects, likely because it decreases glycolysis only partially and transiently.
Pulsatile microvascular blood flow imaging by short-time Fourier transform analysis of ultrafast laser holographic interferometry (2015)

We report on wide-field imaging of pulsatile microvascular blood flow in the exposed cerebral cortex of a mouse by holographic interferometry. We recorded interferograms of laser light backscattered by the tissue, beating against an off-axis reference beam with a 50 kHz framerate camera. Videos of local Doppler contrasts were rendered numerically by Fresnel transformation and short-time Fourier transform analysis. This approach enabled instantaneous imaging of pulsatile blood flow contrasts in superficial blood vessels over 256 x 256 pixels with a spatial resolution of 10 microns and a temporal resolution of 20 ms.
Perpendicular recording near 100 Gb/in/sup 2/ (2003)

Theoretical analyses have projected perpendicular recording capable of achieving ultimate areal densities greater than longitudinal recording systems. For perpendicular recording to supplant longitudinal recording, laboratory demonstrations will need to be made which intercept or exceed the areal densities achieved by state-of-the-art longitudinal recording demonstrations. Recent demonstrations have come close to eliminating the gap between these technologies. In this paper, recording experiments at areal densities in the 60 to 100 Gb/in/sup 2/ range will be described. It will be shown that the head field from conventional single-pole writers is not well localized to the data track and that if the media do not have sufficiently high nucleation thresholds, this fringe field will gradually erase data on the adjacent track if the track pitch is too aggressive. Extension of this technology to densities of the order of 1 Tb/in/sup 2/ will require heads that reduce the extent of the fringe field without sacrificing available on-track field.
Electrolyte anion-assisted charge transportation in poly(oxoammonium cation/nitroxyl radical) redox gels (2012)

Charge transport in poly(oxoammonium cation/nitroxyl radical) redox gels was investigated by chronoamperometry on the basis of an infinite-diffusion model without a volume change during the redox reaction and a limit of the diffusion distance by means of fabricating the bulk solid gels. Charge transportation in the redox gels was found to be dominated by the mobility of electrolyte anion rather than the concentration of redox centers. Furthermore, the ionic conductivity of the redox gel was estimated to be almost one third of that of the liquid electrolyte. The result indicates that larger ionic conductivity in the gel also brings faster charge transportation through the redox centers.
Palladium‐Catalyzed Syntheses of Polyethynyl‐Substituted 2,2′‐Bithiophenes (1996)

Abstract The syntheses of polyethynyl‐substituted 2,2′‐bithiophenes 2 and related 5,5′‐dicarbaldehyde derivatives 1 are described. The treatment of easily available polybrominated 2,2′‐bithiophenes 3 and 2,2′‐bithiophene‐5,5′‐dicarbaldehydes 4 with phenyl or (trimethylsilyl)acetylene in the presence of Pd II and Cu I in (i‐Pr) 2 NH yields substituted polyethynyl‐2,2′‐bithiophene compounds. The Me 3 Si protecting groups can be removed by protodesilylation under basic conditions to give the corresponding terminal ethynyl groups. These polyethynyl‐bithiophenes could be interesting precursors for the synthesis of macrocycles with interesting properties.
Synthesis, characterization, and cleavage reactions of substituted cyclopropenium salts of di-.mu.-chlorotetrachlorodiplatinate(2-) and di-.mu.-chloro-tetrachlorodipalladate(2-) (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis, characterization, and cleavage reactions of substituted cyclopropenium salts of di-.mu.-chlorotetrachlorodiplatinate(2-) and di-.mu.-chloro-tetrachlorodipalladate(2-)Daniel C. Harris and Harry B. GrayCite this: Inorg. Chem. 1974, 13, 9, 2250–2255Publication Date (Print):September 1, 1974Publication History Published online1 May 2002Published inissue 1 September 1974https://pubs.acs.org/doi/10.1021/ic50139a038https://doi.org/10.1021/ic50139a038research-articleACS PublicationsRequest reuse permissionsArticle Views104Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Ionic Dissociation (2016)

This document contains recommendations for terminology in mass spectrometry. Development of standard terms dates back to 1974 when the IUPAC Commission on Analytical Nomenclature issued recommendations on mass spectrometry terms and definitions. In 1978, the IUPAC Commission on Molecular Structure and Spectroscopy updated and extended the recommendations and made further recommendations regarding symbols, acronyms, and abbreviations. The IUPAC Physical Chemistry Division Commission on Molecular Structure and Spectroscopy’s Subcommittee on Mass Spectroscopy revised the recommended terms in 1991 and appended terms relating to vacuum technology. Some additional terms related to tandem mass spectrometry were added in 1993 and accelerator mass spectrometry in 1994. Owing to the rapid expansion of the field in the intervening years, particularly in mass spectrometry of biomolecules, a further revision of the recommendations has become necessary. This document contains a comprehensive revision of mass spectrometry terminology that represents the current consensus of the mass spectrometry community.
Co-expression of B7–1 with Interleukin-12 Enhances Vaccine-induced Antitumour Immunity in Experimental Myeloma (1998)

There has been little improvement in the treatment of multiple myeloma over the past 25 years. Disease inevitably reoccurs in patients who receive chemotherapy of melphalan and prednisone or combinations of alkylating agents. Autologous hematopoietic stem cell transplantation can increase remission rates and prolong diseasefree and overall survival. However, all transplanted myeloma patients ultimately relapse. The ineffectiveness of conventional induction and maintenance therapies in multiple myeloma has motivated the search for alternative treatment strategies. Immunotherapy involving cancer vaccines is one such alternative where the intent is to induce a host antitumour immune response. In this study, we employed a syngeneic murine model of multiple myeloma developed in our laboratory to examine the consequence of combined expression of interleukin-12 (IL-12) and the B7-1 costimulatory molecule on myeloma immuno genicity. We show that the IL-12/B7-1 immunogene combination was efficacious in evoking systemic protective immunity against unmodified parental myeloma cells. These findings suggest that autologous myeloma cells engineered to co-express IL-12 and B7-1 may hold promise as cancer vaccines for consolidation therapy in multiple myeloma.
Effective dielectric constant of top grounded coplanar waveguide on liquid crystal superstrate (2013)

Abstract The effective dielectric constant of the top grounded coplanar waveguide with a liquid crystal (LC) superstrate for phase shifting applications is investigated in the frequency range of 30–60 GHz. Two nematic LC mixtures, namely E7 and MDA‐00‐3506, are used as the superstrate. The measurements show that MDA‐00‐3506 offers higher values of phase shift per millimeter than its E7 counterpart. In particular, the MDA‐00‐3506 provides 3.14°/mm, whereas E7 gives 2.79°/mm at 60 GHz. The results of the dielectric constants from measurement and computer modeling are found to agree to within 5%. For the modeling, a comprehensive finite element package predicting the local alignment of LC molecules and effective dielectric constant at different bias voltages and frequencies are used. © 2013 Wiley Periodicals, Inc. Microwave Opt Technol Lett 55:1416–1418, 2013; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27564
ChemInform Abstract: Studies Toward Practical Synthesis of (20S)‐Camptothecin Family Through Catalytic Enantioselective Cyanosilylation of Ketones: Improved Catalyst Efficiency by Ligand‐Tuning. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Accurate, conformation-dependent predictions of solvent effects on protein ionization constants (2007)

Predicting how aqueous solvent modulates the conformational transitions and influences the pKa values that regulate the biological functions of biomolecules remains an unsolved challenge. To address this problem, we developed FDPB_MF, a rotamer repacking method that exhaustively samples side chain conformational space and rigorously calculates multibody protein-solvent interactions. FDPB_MF predicts the effects on pKa values of various solvent exposures, large ionic strength variations, strong energetic couplings, structural reorganizations and sequence mutations. The method achieves high accuracy, with root mean square deviations within 0.3 pH unit of the experimental values measured for turkey ovomucoid third domain, hen lysozyme, Bacillus circulans xylanase, and human and Escherichia coli thioredoxins. FDPB_MF provides a faithful, quantitative assessment of electrostatic interactions in biological macromolecules.
The Effect of AgK114 on Wound Healing (2006)

AgK114 is a newly isolated membrane-associated protein which is expressed on keratinocytes. Its expression is restricted to dermal sheath cells near sebaceous glands in normal skin. However, it is transiently induced by UV exposure or injury stimulation (Tatefuji T. et al., Biol. Pharm. Bull., 27, 1742-1749, 2004). Thus, the expression pattern of AgK114 suggested its potential role in wound healing response. We report here that expression of AgK114 is induced in the initial 24 h at the edge keratinocytes during keratinocyte migration, followed by disappearance once epithelialization is completed in the murine excisional wound model. We also demonstrate that exogenous recombinant mouse AgK114FL promoted wound healing process. Mouse AgK114FL up-regulated pro-matrix-metalloproteinase-9, vascular endothelial growth factor, transforming growth factor-beta, IL-6, and IL-1beta production in the early stage of wound tissue. Moreover, mouse AgK114FL induced the matrix-metalloproteinase-9 activity of wound fibroblasts prepared from impaired skin in the presence of proinflammatory cytokines. These results suggest that the AgK114 participates in the wound response during the healing process, and promotes wound repair.
Transmission mode ion/ion reactions in the radiofrequency‐only ion guide of hybrid tandem mass spectrometers (2009)

Transmission mode ion/ion reactions have been performed within the first quadrupole, the Q0 radiofrequency (RF)-only quadrupole, of two types of hybrid tandem mass spectrometers (viz., triple quadrupole/linear ion trap and QqTOF instruments). These transmission mode reactions involved the storage of either the reagent species and the transmission of the analyte species through the Q0 quadrupole for charge inversion reactions or the storage of the analyte ions and transmission of the reagent ions as in charge reduction experiments. A key advantage to the use of transmission mode ion/ion reactions is that they do not require any instrument hardware modifications to provide interactions of oppositely charged ions and can be implemented in any instrument that contains a quadrupole or linear ion trap. The focus of this work was to investigate the potential of using the RF-only quadrupole ion guide positioned prior to the first mass-resolving element in a tandem mass spectrometer for ion/ion reactions. Two types of exemplary experiments have been demonstrated. One involved a charge inversion reaction and the other involved a charge reduction reaction in conjunction with ion parking. Ion/ion reactions proved to be readily implemented in Q0 thereby adding significantly greater experimental flexibility in the use of ion/ion reaction experiments with hybrid tandem mass spectrometers.
Supramolekulare Kontrolle der mechanischen Eigenschaften feuerabschirmender biomimetischer Perlmuttanaloga (2010)

Keine Probleme mit Hitze: Kolloidale Bausteine aus einem harten Kern und einer weichen Schale ermöglichen die Selbstorganisation zu permuttartigem Papier in großem Maßstab. Stärke und Steifheit des Materials lassen sich mithilfe supramolekularer ionischer Bindungen steuern. Diese leichten biomimetischen Materialien zeigen ausgezeichnete und einstellbare mechanische Eigenschaften und bieten Schutz vor Hitze und Feuer. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Structural Correlations: Design Levers for Performance and Durability of Catalyst Layers (2013)

Abstract not Available.