gebhart/patrepeval huggingface dataset:
A 300Hz 19b DR capacitive accelerometer based on a versatile front end in a 5<sup>th</sup>-order &#x0394;&#x03A3; loop (2009)

This paper presents a 5 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sup> -order DeltaSigma capacitive accelerometer. The DeltaSigma loop is implemented in mixed signal, the global 5 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">th</sup> -order filter having a 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">nd</sup> -order analog and a 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> -order digital part. The system can be used with a wide range of sensors, because the mixed-signal front end is programmable. The ASIC developed comprises a voltage-mode preamplifier, two parallel demodulators implementing CDS, and a 7-bit Flash ADC. The latter drives a 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> -order digital filter, which can be configured for different sensor parameters in order to ensure overall loop stability and optimize the noise performance. With a low-noise MEMS sensor, the system achieves a 19-bit DR and a 16-bit SNR, both over a 300 Hz bandwidth.
Novel High-Rate, All Solid-State, Sodium and Lithium/Organosulfur Batteries (1989)

This paper is an abstract for a talk to be given at the Battery and Electrochemical Contractor's Conference. The paper gives a brief description of sodium and lithium/organosulfur batteries. (JEF)
Cerebral cavernous malformations proteins inhibit Rho kinase to stabilize vascular integrity (2010)

Endothelial cell-cell junctions regulate vascular permeability, vasculogenesis, and angiogenesis. Familial cerebral cavernous malformations (CCMs) in humans result from mutations of CCM2 (malcavernin, OSM, MGC4607), PDCD10 (CCM3), or KRIT1 (CCM1), a Rap1 effector which stabilizes endothelial cell-cell junctions. Homozygous loss of KRIT1 or CCM2 produces lethal vascular phenotypes in mice and zebrafish. We report that the physical interaction of KRIT1 and CCM2 proteins is required for endothelial cell-cell junctional localization, and lack of either protein destabilizes barrier function by sustaining activity of RhoA and its effector Rho kinase (ROCK). Protein haploinsufficient Krit1(+/-) or Ccm2(+/-) mouse endothelial cells manifested increased monolayer permeability in vitro, and both Krit1(+/-) and Ccm2(+/-) mice exhibited increased vascular leak in vivo, reversible by fasudil, a ROCK inhibitor. Furthermore, we show that ROCK hyperactivity occurs in sporadic and familial human CCM endothelium as judged by increased phosphorylation of myosin light chain. These data establish that KRIT1-CCM2 interaction regulates vascular barrier function by suppressing Rho/ROCK signaling and that this pathway is dysregulated in human CCM endothelium, and they suggest that fasudil could ameliorate both CCM disease and vascular leak.
Supplementary File 4 from Genome-Wide Functional Synergy between Amplified and Mutated Genes in Human Breast Cancer (2023)

Supplementary File 4 from Genome-Wide Functional Synergy between Amplified and Mutated Genes in Human Breast Cancer
Applicability and Safety of in Vitro Skin Expansion Using a Skin Bioreactor: A Clinical Trial (2014)

This study confirmed the safety and applicability of the in vitro skin bioreactor, and further studies are needed to develop methods for increasing the skin expansion rate.
Shading correction of camera captured document image with depth map information (2015)

Camera modules have become more popular in consumer electronics and office products. As a consequence, people have many opportunities to use a camera-based device to record a hardcopy document in their daily lives. However, it is easy to let undesired shading into the captured document image through the camera. Sometimes, this non-uniformity may degrade the readability of the contents. In order to mitigate this artifact, some solutions have been developed. But most of them are only suitable for particular types of documents. In this paper, we introduce a content-independent and shape-independent method that will lessen the shading effects in captured document images. We want to reconstruct the image such that the result will look like a document image captured under a uniform lighting source. Our method utilizes the 3D depth map of the document surface and a look-up table strategy. We will first discuss the model and the assumptions that we used for the approach. Then, the process of creating and utilizing the look-up table will be described in the paper. We implement this algorithm with our prototype 3D scanner, which also uses a camera module to capture a 2D image of the object. Some experimental results will be presented to show the effectiveness of our method. Both flat and curved surface document examples will be included.
ChemInform Abstract: STRAINED β‐LACTAMS. REACTIVITY OF 6‐AZABICYCLO(3.2.0)HEPTAN‐7‐ONE AND DERIVATIVES (1978)

Abstract Reaktionen des Cyclopenten‐Chlorsulfonylisocyanat‐Addukts (II) mit Nukleophilen verlaufen unter Öffnung des Lactamringes und Bildung cis‐disubstituierter Cyclopentane.
Development of a methanol reformer for fuel cell vehicles (2003)

Vehicles powered by fuel cells are from an environmentalaspect superior to the traditional automobile using internalcombustion of gasoline. Power systems which are based upon fuelcell technology re ...
Robust trajectory planning for robotic manipulators under payload uncertainties (1987)

A number of trajectory planning algorithms are available for determining the joint torques, positions, and velocities required to move a manipulator along a given geometric path in minimum time. These schemes require knowledge of the robot's dynamics, which in turn depend upon the characteristics of the payload which the robot is carrying. In practice, the dynamic properties of the payload will not be known exactly, so that the dynamics of the robot, and hence the required joint torques, must be calculated for a nominal set of payload characteristics. But since these trajectory planners generate nominal joint torques which are at the limits of the robot's capabilities, moving the robot along the desired geometric path at speeds calculated for the nominal payload may require torques which exceed the robot's capabilities. In this paper, bounds on joint torque uncertainties are derived in terms of payload uncertainties. Using these bounds, a new trajectory planner is developed to incorporate payload uncertainties such that all the trajectories generated can be realized with given joint torques. Finally, the trajectory planner is applied to the first three joints of the Bendix PACS arm, a cylindrical robot to demonstrate its use and power.
Central tolerance and autoimmune diseases (2006)

Central tolerance is established by the repertoire selection of immature T lymphocytes in the thymus, avoiding autoimmune responses to self-antigens. Differential ligand-TCR interactions that result in positive and negative selection initiate differential intracellular signals that, in turn, lead to the survival-or-death decision of immature thymocytes. TCR signal dysregulation due to the mutation of ZAP-70 or defective apoptosis of autoreactive thymocytes due to the deficiency of pro-apoptotic protein Bim impair tolerance and cause autoimmunity. Thymic repertoire selection also induces the development of CD25(+)CD4(+) regulatory T cells, which play important roles for maintaining peripheral tolerance. Furthermore, the establishment of central tolerance requires the development of thymic medulla that is mediated by the activation of NF-kappaB signaling pathway, promiscuous expression of tissue-specific self-antigens by medullary epithelial cells that is regulated by AIRE, and cortex-to-medulla migration of developing thymocytes that is regulated by CCR7-mediated chemokine signals.
VEHICLE ORIENTATION ANALYSIS USING EIGEN COLOR, EDGE MAP, AND NORMALIZED CUT CLUSTERING (2010)

This paper proposes a novel approach for estimating vehicles' orientations from still images using "eigen color" and edge map through a clustering framework. To extract the eigen color, a novel color transform model is used for roughly segmenting a vehicle from its background. The model is invariant to various situations like contrast changes, background, and lighting. It does not need to be re-estimated for any new vehicles. In this eigen color space, different vehicle regions can be easily identified. However, since the problem of object segmentation is still ill-posed, only with this model, the shape of a vehicle cannot be well extracted from its background and thus affects the accuracy of orientation estimation. In order to solve this problem, the distributions of vehicle edges and colors are then integrated together to form a powerful but high-dimensional feature space. Since the feature dimension is high, the normalized cut spectral clustering (Ncut) is then used for feature reduction and orientation clustering. The criterion in Ncut tries to minimize the ratio of the total dissimilarity between groups to the total similarity within the groups. Then, the vehicle orientation can be analyzed using the eigenvectors derived from the Ncut result. The proposed framework needs only one still image and is thus very different to traditional methods which need motion features to determine vehicle orientations. Experimental results reveal the superior performances in vehicle orientation analysis.
Wear behavior of additive manufactured zirconia (2020)

Complete consolidation of ceramic particles is feasible for SLA, but print directionality is well acknowledged to be a source of structural anisotropy. By varying build direction of SLA zirconia specimens, pin-on-disk tests were carried out to evaluate any differences in wear behavior and phase composition with respect to laminar architecture. All combinations of horizontal and vertical pin-disk combinations demonstrated equivalent wear coefficients and phase transformation from monoclinic to tetragonal zirconia but do exhibit a nominal trend in run-in wear. Given that microstructural consolidation of AM ceramics is highly dependent on debind and/or sintering rather than print parameters the absence of anisotropy introduce by print parameters could benefit the application and development around AM ceramics.
Supplementary Methods, Figure Legend from Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1 (2023)

&lt;p&gt;PDF file - 149K&lt;/p&gt;
X-Ray Diffraction Curves from Mosaic Crystals at Near-Normal Incidence Angles (1989)

We obtained data supporting our previous calculations of X-ray diffraction curves from mosaic crystals at near-normal incidence angles. The data were collected from copper crystals with mosaic spreads of 1.2° and 0.4° by scanning the photon energy in the vicinity of 3 keV at a synchrotron-radiation beamline designed for surface science. The 1.2° mosaic crystal showed Bragg-peak widths markedly dependent on the off-normal angle of incidence while the dependence for the 0.4° crystal was much weaker. The observed peak widths agree with calculations if an energy resolution of 2.1 eV is assumed for beamline 1A of the Photon Factory, at which the experiment was conducted.
BLAST Large-scale Extragalactic Submillimeter Survey Results (2010)

The Balloon-borne Large Aperture Submillimeter Telescope (BLAST) is a suborbital surveying experiment designed to study the evolutionary history and processes of star formation in local galaxies (including the Milky Way) and galaxies at cosmological distances. The BLAST continuum camera, which consists of 270 detectors distributed between three arrays, observes simultaneously in broadband (30%) spectral windows at 250, 350, and 500µm, akin to the SPIRE instrument on Herschel. The optical design is based on a 2m diameter telescope, providing nearly diffraction-limited resolution of 36“ at 250µm. BLAST performed a test flight in 2003 and has since made two scientifically productive long-duration balloon flights: a 100 hour flight from ESRANGE (Kiruna), Sweden to Victoria Island, northern Canada in 2005 June; and a 250 hour, circumpolar flight from McMurdo Station, Antarctica in 2006 December. A deep, confusion limited, 0.8 deg² map nested in a wide, 8.6 deg² map in the direction of GOODS-South was made during the 2006 flight. Approximately half of all the light from stars is absorbed and reprocessed by dust. The resulting emission is grey body with a temperature near 30K. While it is believed that this radiation makes up the Far Infrared Background (FIRB) detected by COBE, it had not been resolved into individual galaxies. Combining BLAST data with data from Spitzer in the same region, we determine that at 500µm all of the FIRB comes from sources that are identified in deep 24µm surveys and that 70% of the FIRB comes from sources with z>1.2. Furthermore, we determine the number of galaxies as a function of flux and frequency in the submillimeter revealing a distinct evolution in the galaxy population from low to high redshift. The BLAST collaboration acknowledges the support of NASA, NSF Office of Polar Programs, the CSA (Canada), the STFC (UK), and NSERC (Canada).
The Bitsy/sup TM/ Spacecraft Kernel: reducing mission cost with modular architecture and miniature technology (2002)

AeroAstro has adopted several advances in technology and architecture that have enabled significant reduction in cost and increase in flexibility for multiple nanosatellite missions. This Bitsy/sup TM/ Spacecraft Kernel technology will enable recurring spacecraft mission costs of under /spl epsi/, including space and ground systems and launch interfaces. This is made possible by: a standardized core of spacecraft capabilities based on commercial-off-the-shelf technologies; and miniaturization, which reduces recurring costs and makes a minimal demand on launch vehicle services. The spacecraft 'kernel', as opposed to bus, does not have a traditional division into discrete subsystems, but rather manages power, thermal control, ACDS, C&DH, and communications in a package of a few kilograms. Bitsy's small size, light weight, and unique extensible architecture enables a variety of customizations to be added as needed to expand the range of achievable missions. In principle, the size and complexity of payloads Bitsy can accommodate is limitless.
Ionic Liquids as Operating Fluids in High Pressure Applications (2007)

Abstract During the past years a growing number of scientists and engineers have investigated ionic liquids because of their outstanding advantages in several areas. Their unique physical properties and specific chemical behavior make these liquids very interesting for new and innovative applications. For commercial implementation ionic liquids have to meet a number of requirements. For use in high pressure applications they should have a low compressibility, an adjustable gas solubility and a superior lubricating ability. A screening of the relevant parameters was conducted in several experimental setups built for these purposes. Most of these parameters were also examined under long term conditions with regard to real process conditions and safety guarantee in possible high pressure applications. A major application is the compression of oxygen using ionic liquid as operating fluid. Besides, there are many more applications where the superior chemical and physical properties of ionic liquids are of high potential benefit.
Experimental Performance of R-1234yf and R-1234ze as Drop-in Replacements for R-134a in Domestic Refrigerators (2012)

Concerns about anthropogenic climate change have generated an interest in low global warming potential (GWP) refrigerants and have spawned policies and regulations that encourage the transition to low GWP refrigerants. Recent research has largely focused on hydrofluoroolefins (HFOs), including R-1234yf (GWP = 4) as a replacement for R-134a (GWP = 1430) in automotive air-conditioning applications. While R-1234yf and R-1234ze (GWP = 6) have been investigated theoretically as a replacements for R-134a in domestic refrigeration, there is a lack of experimental evidence. This paper gives experimental performance data for R-1234yf and R-1234ze as drop-in replacements for R134a in two household refrigerators one baseline and one advanced technology. An experiment was conducted to evaluate and compare the performance of R-134a to R-1234yf and R-1234ze, using AHAM standard HRF-1 to evaluate energy consumption. These refrigerants were tested as drop-in replacements, with no performance enhancing modifications to the refrigerators. In Refrigerator 1 and 2, R-1234yf had 2.7% and 1.3% higher energy consumption than R-134a, respectively. This indicates that R-1234yf is a suitable drop-in replacement for R-134a in domestic refrigeration applications. In Refrigerator 1 and 2, R-1234ze had 16% and 5.4% lower energy consumption than R-134a, respectively. In order to replace R-134a with R-1234ze inmore » domestic refrigerators the lower capacity would need to be addressed, thus R-1234ze might not be suitable for drop-in replacement.« less
Nanoparticle Films and Photonic Crystal Multilayers from Colloidally Stable, Size-Controllable Zinc and Iron Oxide Nanoparticles (2011)

We report a facile sol-gel synthesis of colloidally stable Fe(2)O(3) and ZnO nanoparticles in alcoholic solvents, ROH, where R = methyl, ethyl, n-propyl, isopropyl, and tert-butyl. We show that nanoparticles of ZnO (4-42) nm and Fe(2)O(3) (4-38 nm) monotonically increase in size upon increasing the alkyl chain length and branching of the alcohol solvent. These colloidally stable and size-controllable metal oxide nanoparticles enable the formation of high optical quality films and photonic crystal multilayers whose component layer thickness, refractive index, porosity, and surface area are found to scale with the nature of the alcohol. Utility of these colloidally stable nanoparticles is demonstrated by preparation of one-dimensional porous photonic crystals comprising ncZnO/ncWO(3) and ncFe(2)O(3)/ncWO(3) multilayers whose photonic stop band can be tuned by tailoring nanoparticle size. Myriad applications can be envisaged for these nanoparticle films in, for example, heterogeneous catalysis, photocatalysis, electrocatalysis, chemical sensors, and solar cells.
A Fuel Cell Assisted Single-Phase Multi-Port Uninterruptible Power Supply with Finite Control Set Model Predictive Controller (2021)

Increasing tendency in online businesses and work from home, attracted many businesses and individuals to consider single-phase uninterruptible power supplies (UPSs). However, low power UPSs are normally incapable of operating for extended time periods. In order to extend UPS ranges, researchers integrated auxiliary energy sources to UPSs. However, integrating auxiliary power sources require additional power electronics active and passive components. This will result in low power density and bulky UPSs. To overcome this issue, multi-port converters have been proposed as an alternative to employing multiple converters. Nevertheless, using multi-port converters require more advanced control methods. This paper proposes a novel multi-port UPS with a finite control set model predictive controller. Simulations are conducted to demonstrate the effectiveness of the proposed converter. The results show the load current THD of 0.77%, resilient transient response, and efficiencies up to 97.5% using SiC MOSFETs.
A Novel, Multifunctional c-Cbl Binding Protein in Insulin Receptor Signaling in 3T3-L1 Adipocytes (1998)

The protein product of the c-Cbl proto-oncogene is prominently tyrosine phosphorylated in response to insulin in 3T3-L1 adipocytes and not in 3T3-L1 fibroblasts. After insulin-dependent tyrosine phosphorylation, c-Cbl specifically associates with endogenous c-Crk and Fyn. These results suggest a role for tyrosine-phosphorylated c-Cbl in 3T3-L1 adipocyte activation by insulin. A yeast two-hybrid cDNA library prepared from fully differentiated 3T3-L1 adipocytes was screened with full-length c-Cbl as the target protein in an attempt to identify adipose-specific signaling proteins that interact with c-Cbl and potentially are involved in its tyrosine phosphorylation in 3T3-L1 adipocytes. Here we describe the isolation and the characterization of a novel protein that we termed CAP for c-Cbl-associated protein. CAP contains a unique structure with three adjacent Src homology 3 (SH3) domains in the C terminus and a region showing significant sequence similarity with the peptide hormone sorbin. Both CAP mRNA and proteins are expressed predominately in 3T3-L1 adipocytes and not in 3T3-L1 fibroblasts. CAP associates with c-Cbl in 3T3-L1 adipocytes independently of insulin stimulation in vivo and in vitro in an SH3-domain-mediated manner. Furthermore, we detected the association of CAP with the insulin receptor. Insulin stimulation resulted in the dissociation of CAP from the insulin receptor. Taken together, these data suggest that CAP represents a novel c-Cbl binding protein in 3T3-L1 adipocytes likely to participate in insulin signaling.
Bundle Adjustment for Markerless Body Tracking in Monocular Video Sequences (2003)

CVLAB
ChemInform Abstract: C—F Activation of Hydrofluorocarbons (HFCs) Mediated by Aluminum Reagents. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Data from Tumor Engraftment in Nude Mice and Enrichment in Stroma- Related Gene Pathways Predict Poor Survival and Resistance to Gemcitabine in Patients with Pancreatic Cancer (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; The goal of this study was to evaluate prospectively the engraftment rate, factors influencing engraftment, and predictability of clinical outcome of low-passage xenografts from patients with resectable pancreatic ductal adenocarcinoma (PDA) and to establish a bank of PDA xenografts.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; Patients with resectable PDA scheduled for resection at the Johns Hopkins Hospital were eligible. Representative pieces of tumor were implanted in nude mice. The status of the &lt;i&gt;SMAD4&lt;/i&gt; gene and content of tumor-generating cells were determined by immunohistochemistry. Gene expression was carried out by using a U133 Plus 2.0 array. Patients were followed for progression and survival.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; A total of 94 patients with PDA were resected, 69 tumors implanted in nude mice, and 42 (61%) engrafted. Engrafted carcinomas were more often &lt;i&gt;SMAD4&lt;/i&gt; mutant, and had a metastatic gene expression signature and worse prognosis. Tumors from patients resistant to gemcitabine were enriched in stroma-related gene pathways. Tumors sensitive to gemcitabine were enriched in cell cycle and pyrimidine gene pathways. The time to progression for patients who received treatment with gemcitabine for metastatic disease (&lt;i&gt;n&lt;/i&gt; = 7) was double in patients with xenografts sensitive to gemcitabine.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusion:&lt;/b&gt; A successful xenograft was generated in 61% of patients attempted, generating a pool of 42 PDA xenografts with significant biological information and annotated clinical data. Patients with PDA and &lt;i&gt;SMAD4&lt;/i&gt; inactivation have a better engraftment rate. Engraftment is a poor prognosis factor, and engrafted tumors have a metastatic gene expression signature. Tumors from gemcitabine-resistant patients were enriched in stromal pathways. &lt;i&gt;Clin Cancer Res; 17(17); 5793–800. ©2011 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;