gebhart/patrepeval huggingface dataset:
Bias-Free Operational UTC-PD above 110 GHz and Its Application to High Baud Rate Fixed-Fiber Communication and W-Band Photonic Wireless Communication (2016)

We present the design of a bias-free uni-travelling-carrier photodiode (UTC-PD) that is operational above 110 GHz, and its application to 100-GBd fixed-fiber communication and 109-GHz carrier-photonic wireless communication for advanced optical networks. The design and analysis for bias-free operation were explained in detail using the carrier concentration in the photo-absorption layer and carrier collector layer. In the experimental results, the developed UTC-PD with back-illuminated structure exhibited a wide 3-dB bandwidth of over 110 GHz at 0 V. For fixed-fiber communications, a high-baud-rate photoreceiver based on the UTC-PD was fabricated. Eye diagrams showed clear openings at up to 107 GBd and high photo-currents of 3-7 mA at 100 GHz signal light were observed at zero-bias. Assuming photonic wireless communication using photonic power supply through optical fiber, the developed UTC-PD contributed to reducing bias feeds to the photoreceiver module. Additionally, low power consumption was achieved when using the newly developed 110 GHz InP-PHEMT amplifier with the UTC-PD.
[Hazard for human health and life by unintentional use of synthetic sibutramine, which was sold as Chinese herbal product "meizitanc"]. (2007)

The medicine containing sibutramine should be used under the strict medical control. For safety of the patients all herbal products should be buy from authorized her
Inducing Disorder in Order: Hierarchically Porous Covalent Organic Framework Nanostructures for Rapid Removal of Persistent Organic Pollutants (2019)

The key factor responsible for fast diffusion and mass transfer through a porous material is the availability of a widely open pore interior having complete accessibility from their surface. However, because of their highly stacked nature, ordered two-dimensional (2D) materials fail to find real-world applicability, as it is difficult to take advantage of their complete structure, especially the inner cores. In this regard, three-dimensional (3D) nanostructures constructed from layered two-dimensional crystallites could prove to be advantageous. However, the real challenge is to cultivate a porous nanostructure with ordered pores where the pores are surrounded by crystalline walls. Herein, a simple yet versatile in situ gas-phase foaming technique has been employed to address these cardinal issues. The use of baking soda leads to the continuous effervescence of CO<sub>2</sub> during the crystallization of foam, which creates ripples and fluctuations on the surface of the 2D crystallites. The induction of ordered micropores within the disordered 3D architecture synergistically renders fast diffusion of various guests through the interconnected pore network. The high-density defects in the hierarchically porous structure help in ultrafast adsorption (<10 s) of various pollutants (removal efficiency of 99%) from water, all of which would lead to significant environmental benefit. The pseudo-second-order rate constant for the BPA pollutant is 182.3 g mg<sup>-1</sup> min<sup>-1</sup>, which is the highest among all the literature reports to date. The high removal efficiency (highest efficiency of 94% and average efficiency of 70%) of a persistent organic pollutant has been attended for the first time.
Precision measurement of tribocharging in acoustically levitated sub-millimeter grains (2020)

Contact electrification of dielectric grains forms the basis for a myriad of physical phenomena. However, even the basic aspects of collisional charging between grains are still unclear. Here, we develop a new experimental method, based on acoustic levitation, which allows us to controllably and repeatedly collide two sub-millimeter grains and measure the evolution of their electric charges. This is, therefore, the first tribocharging experiment to provide complete electric isolation for the grain-grain system from its surroundings. We use this method to measure collisional charging rates between pairs of grains for three different material combinations: polyethylene-polyethylene, polystyrene-polystyrene, and polystyrene-sulfonated polystyrene. The ability to directly and noninvasively collide particles of different constituent materials, chemical functionality, size, and shape opens the door to detailed studies of collisional charging in granular materials.
Flavor (2004)

We present Flavor, a formal language for audio-visual object representation, that has been developed to describe any coded multimedia data in formats such as GIF, JPEG and MPEG. The language comes with a translator for generating C++/Java code from the Flavor description, and the generated code can include bitstream reading, writing and tracing methods. Since Version 5.0, the translator has been enhanced to also support XML. With the enhanced translator, the generated C++/Java code can include a method for producing XML documents that correspond to the bitstreams described by Flavor. The description can also be used to generate a corresponding XML schema. Additionally, a software tool for converting XML representation of multimedia data back into bitstream form is provided.
Demonstration of Raman gain at 800 nm in single-mode fiber and its potential application to biological sensing and imaging (2009)

Optical amplification prior to photon-to-electron conversion improves detection sensitivity in spectroscopic and imaging applications. Here we report the first experimental demonstration of Raman amplification in a single-mode fiber at wavelengths near 800 nm. This approach can potentially enable fast real-time optical sensing and imaging in the wavelength band that benefits from both low water absorption and the availability of high-power Ti:Sapphire lasers.
Superconducting nanowire single-photon detector on thin- film lithium niobate photonic waveguide (2020)

We integrate niobium nitride superconducting nanowire single-photon detectors (SNSPDs) on thin-film lithium niobate (LN) photonic waveguides. Further development of this technology may push towards more complex circuits and functionalities on this already promising platform.
Compact coder for component color television (1990)

A study of predictive coding of component TV signals for compression to transmit at rates that give good picture quality is reported. Designing predictors for minimum mean square prediction error is effective, both for luminance and chrominance signals. Predictors designed in this manner were found to be as good as or better than all other predictors tested. Quantizers designed for minimum mean square system error were primarily used in this study. A programmable testbed was built to permit quick comparisons. Predictors were compared on the testbed using a 2-b quantizer in order to have adequate system error to display visible differences. For simple intrafield coding, component signals compressed for transmission at 30 Mb/s gave about equivalent quality to an NTSC composite signal coded directly for transmission at 45 Mb/s. With 45-Mb/s transmission, component signal coding showed no detectable degradation on close inspection of real pictures. Maximum chrominance changes on test patterns yield visually detectable chrominance slope overload.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Symptoms Versus Impairment in Adults With ADHD: Intercorrelations of the BRIEF-A, CAARS, and TOVA (2016)

Objective: The aim of this study is to explore the connections within and between three measures of adult ADHD: the Behavior Rating Inventory of Executive Function–Adult Version (BRIEF-A)–Self-Report, Conners’ Adult ADHD Rating Scale–Investigator-Rated (CAARS-Inv), and Test of Variables of Attention (TOVA). Method: Data of 89 adults with ADHD (ages = 18-54, 46% females) who were assessed using these measures during pretreatment visits of a randomized study of metadoxine XR were analyzed. Results: The CAARS-Inv and TOVA did not correlate. The BRIEF-A correlated extensively with both the CAARS-Inv and TOVA, primarily via its Behavioral Regulation Index (BRI). The BRIEF-A Metacognition Index correlated with the CAARS-Inv inattentive score, while the BRI correlated with the CAARS-Inv hyperactive-impulsive score. Within the CAARS and TOVA, inattention and hyperactivity-impulsivity correlated weakly. Conclusion: The measures seem to capture different aspects of adult ADHD. While the CAARS-Inv addresses mainly the domain of symptoms, and the TOVA that of impairment, the BRIEF-A captures aspects of both.
Latest Tests of a Submillimeter-Wave Backward Wave Oscillator (2006)

A 600-700 GHz BWO is currently being rebuilt for testing. Previous tests identified problems with the cathode and materials used in the structure. These were addressed and the BWO is now being assembled for testing in July 2006. The modifications to the design are described and test results will be presented.
Protecting The Spin Coherence of Silicon Vacancy Color Centers from Thermal Noise Using Diamond MEMS (2017)

Spin coherence time, T2*, of the silicon vacancy color center in diamond is limited by thermal phonons existing in the lattice. We show how this process can be engineered by applying static strain using a micro-electro-mechanical system (MEMS) fabricated on diamond. By suppressing the relevant thermal process, we demonstrate the improvement of spin T2*.
Deterministic Frequency and Voltage Enhancements on the POWER10 Processor (2022)

Digital droop sensors (DDSs) with core throttling mitigate microprocessor voltage droops and enable a voltage control loop (undervolting) to offset loadline uplift plus noise effects, protecting reliability <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$V_{\mathrm {DDMAX}}$ </tex-math></inline-formula> . These combine with a runtime algorithm for workload optimized frequency (WOF) that deterministically maximizes core frequency. The combined effect is demonstrated across a range of workloads, including SPEC, and provides up to a 15% frequency boost and a 10% reduction in core voltage.
Stable Metallic Enrichment in Conductive Filaments in TaOx‐Based Resistive Switches Arising from Competing Diffusive Fluxes (2019)

Abstract Oxide‐based resistive‐switching devices hold promise for solid‐state memory technology. Information encoding is accomplished by electrically switching the device between two nonvolatile states with low and high resistance states (LRS/HRS). It is generally accepted that the change between these states is due to the motion of oxygen vacancies forming a continuous (LRS) or gapped (HRS) filament between the electrodes. Direct assessments of filaments are rare due to their small size and the difficulty of locating the filament. Electron microscopy experiments reveal the filament structure and chemistry in TaO 2.0 ± 0.2 ‐based 150 × 150 nm 2 devices with cross‐sectional geometry after forming with power dissipation lower than 1 mW. The filaments appear to be roughly hourglass‐shaped with a diameter of less than 10 nm and are composed of Ta‐rich and O‐poor mostly amorphous material with local compositions as Ta‐rich as TaO 0.4 . The as‐formed HRS has a gap up to 10 nm wide located next to the anode and composed of nearly stoichiometric TaO 2.5 . The tantalum and oxygen distribution is consistent with filaments formed by the motion of both Ta and O driven by temperature gradients (Soret effect) and an electric field. This interpretation points towards a new compact model of resistive‐switching devices.
66‐1: High Resolution Quantum Dot Global Shutter Imagers (2021)

Quantum dot photodetectors are a promising platform technology that ST Microelectronics has developed, scaled‐up, and is ready to commercialize. Our quantum dot‐based global shutter imagers are responsive from UV to SWIR wavelengths at high resolution, high efficiency, and low dark currents, with good reliability and very competitive cost. Sampling to customers is now ready to start.
Fully Self-Aligned Organic Electroluminescent Devices with Dual Sidewall Structures (1999)

Fully self-aligned organic electroluminescent devices with dual sidewall structures were studied. The principal point of the fabrication process was the formation of a sidewall structure using reactive ion etching. A cathode metal was used as a mask for self-alignment and an insulating sidewall structure was formed around the device periphery. The device characteristics were measured after sidewall fabrication. Emission was observed above 3.5 V and luminance was measured to be 1000 cd/m 2 at a current density of 100 mA/cm 2 . After the sidewall fabrication process, wet and photolithographic processes were applied. A luminance of over 3000 cd/m 2 was also observed after the final fabrication process.
An Up-Sampled Particle Filter Fusion Technique and Its Application in Synthetic Aperture Radar Imaging (2021)

Global positioning system (GPS) and inertial measurement units (IMUs) are often combined to produce navigation systems for airborne imaging platforms. The current state-of-the-art radar technology allows for radars to pulse at very high rates. GPS and IMU update rates are not fast enough to accurately report the platform position for each radar pulse. Independent GPS and IMUs cannot provide positional accuracy for long term stability. Traditional techniques, such as the Kalman and particle filter, are used to fuse GPS and IMU measurements. The Kalman filter excels for linear and Gaussian systems whereas the particle filter excels at non-linear and non-Gaussian systems. Sensor fusion techniques are used to help correct for IMU errors and provide the positional accuracy required for synthetic aperture radar (SAR) imaging applications. However, SAR requires the fusion algorithms to provide faster update rates. This paper explores the use of an up-sampled particle filter (UPF) for SAR to provide highly accurate position estimates at sampling frequencies comparable to radar pulse rates and overcome the limitations of standard interpolation techniques. This up-sampled particle filter is proven through simulations and instrumentation with a NovAtel GPS and IMU. The UPF technique allows for the GPS/IMU sampling rate to be different from the radar pulse repetition frequency (PRF) while providing accurate position solutions for each radar pulse capable of compensating for the phase history required for focusing a SAR image. The algorithms are instrumented in a SAR system and the position estimates are further validated and demonstrated through captured SAR images.
Semi-supervised Max-margin Topic Model with Manifold Posterior Regularization (2017)

Supervised topic models leverage label information to learn discriminative latent topic representations. As collecting a fully labeled dataset is often time-consuming, semi-supervised learning is of high interest. In this paper, we present an effective semi-supervised max-margin topic model by naturally introducing manifold posterior regularization to a regularized Bayesian topic model, named LapMedLDA. The model jointly learns latent topics and a related classifier with only a small fraction of labeled documents. To perform the approximate inference, we derive an efficient stochastic gradient MCMC method. Unlike the previous semi-supervised topic models, our model adopts a tight coupling between the generative topic model and the discriminative classifier. Extensive experiments demonstrate that such tight coupling brings significant benefits in quantitative and qualitative performance.
Evidence of a Role for Ki-RAS in the Stimulated Proliferation of Renal Fibroblasts (1999)

Progressive renal fibrosis is driven by a range of cytokines that act via membrane receptors and intracellular signaling cascades to evoke gene transcription events and related responses. The Ras family of GTPases has been implicated in many of these signaling cascades in model systems such as 3T3 fibroblasts. However, the roleof the specific Ras isoforms Ki, Ha, and N in the stimulation of renal fibroblasts has not been defined. In this study, Ras has been inhibited in primate renal fibroblasts (vero cells) using specific phosphorothioate oligodeoxynucleotides (oligos) targeting the three isoforms. Lipofectin transfection with 200 to 400 nM Ki-Ras oligo inhibited the epidermal growth factor- and fibroblast growth factor-stimulated proliferation of vero cells by 25 to 35% with a lesser effect on serum-stimulated growth. Oligos against Ha-Ras and N-Ras were inactive with respect to control oligo. Total cellular Ras protein (estimated by Western blotting) was reduced by 60 to 90% 24 h after transfection with Ki-Ras oligo. N-Ras, Ha-Ras, and control oligos were inactive. Total Ras synthesis over 4 h measured using [35S]-cys/met pulse chase was reduced by approximately 70% by Ki-Ras oligo and not altered by other oligos. The fractional prenylation of Ras was quantified from the discrete bands on polyacrylamide gel electrophoresis and was increased by the Ki-Ras oligo alone. These data demonstrate that these renal fibroblasts predominantly express the Ki isoform of Ras and that this GTPase plays a role in the stimulated proliferation of these cells. Ras GTPases may be a target for the inhibition of processes leading to renal fibrosis.
Demonstration of THz wave generation up to 700 GHz using Mach-Zehnder-modulator-based flat comb generator (2013)

By photomixing of optical two-tone signals, which was extracted from an optical comb signal generated by a Mach-Zehnder-modulator-based flat comb generator (MZ-FCG), generation of cw-THz signal up to 700 GHz was demonstrated. In this system, the frequency accuracy of the THz signal is decided by that of the rf signal driving the MZ-FCG, so that it is expected that the generated THz signal has extremely high frequency accuracy.
Status of Methylthioadenosine Phosphorylase and its Impact on Cellular Response to l-Alanosine and Methylmercaptopurine Riboside in Human Soft Tissue Sarcoma Cells (2004)

The aim of this study was to examine the expression of methylthioadenosine phosphorylase (MTAP) in 21 fresh tumor samples from patients with soft tissue sarcomas (STS) and 11 human soft tissue sarcoma cell lines, and to determine if loss of expression of this enzyme was correlated with increased sensitivity to L-alanosine and/or 6-methylmercaptopurine. We used a polyclonal antibody to measure the expression of MTAP in soft tissue sarcoma cell lines and in fresh tumor samples. Transfection of the HT-1080 cell line with a plasmid containing the cDNA for the MTAP gene was also performed to generate cell lines for in vitro and in vivo comparative sensitivity studies. MTAP was not expressed in 8 of 21 fresh STS tumors. The expression of MTAP was also not detectable in 3 of the 11 soft tissue sarcoma cell lines (HT-1080, HS42, and M-9 110). These three cell lines were more sensitive to L-alanosine, a potent inhibitor of de novo AMP synthesis, and to an inhibitor of de novo purine nucleotide synthesis, 6-methylmercaptopurine riboside (MMPR). The IC50 values for L-alanosine and MMPR were >20-fold lower in MTAP-deficient cells than in MTAP-positive cells. Restoration of MTAP into HT-1080 MTAP-deficient cells also led to decreased sensitivity to L-alanosine and MMPR. An in vivo study using HT-1080 cell tumors with and without MTAP expression confirmed that tumors lacking MTAP were more sensitive to L-alanosine than tumors expressing MTAP. These results provide the basis for selective therapy using inhibitors of de novo purine nucleotide synthesis such as L-alanosine or MMPR to treat patients with STS lacking this enzyme.
Parameterized schematics (VLSI) (2003)

A design capture system is presented that allows parameterized schematics and code to be intermixed freely to produce annotated net lists. A key feature of the system is its extensibility. It provides a small set of powerful abstractions for design description that can easily be extended by users. The system also allows convenient graphical specification of layout generators, and has been used to produce several large VLSI chips.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
A New Synthesis of Aromatic and Heteroaromatic Nitrogen Mustards Via 3-Pyrrolines (1987)

Abstract Reaction of aromatic and heteroaromatic halides with 3-pyrroline gives adducts which can be converted in a three-step process to nitrogen mustards.
Recellularization of decellularized heart valves: Progress toward the tissue-engineered heart valve (2017)

The tissue-engineered heart valve portends a new era in the field of valve replacement. Decellularized heart valves are of great interest as a scaffold for the tissue-engineered heart valve due to their naturally bioactive composition, clinical relevance as a stand-alone implant, and partial recellularization in vivo. However, a significant challenge remains in realizing the tissue-engineered heart valve: assuring consistent recellularization of the entire valve leaflets by phenotypically appropriate cells. Many creative strategies have pursued complete biological valve recellularization; however, identifying the optimal recellularization method, including in situ or in vitro recellularization and chemical and/or mechanical conditioning, has proven difficult. Furthermore, while many studies have focused on individual parameters for increasing valve interstitial recellularization, a general understanding of the interacting dynamics is likely necessary to achieve success. Therefore, the purpose of this review is to explore and compare the various processing strategies used for the decellularization and subsequent recellularization of tissue-engineered heart valves.
Communications Architecture for National Security and Public Safety: Multijurisdictional, Multitechnology Network of Interoperable Networks (2014)

Anytime, anywhere, and any media communications and information transfer across multiple jurisdictions within and between public safety, emergency response, national security and emergency preparedness (PS/ER/NS/EP) communities are becoming increasingly important in preventing and responding to crises. The diversity of networking technologies and network services used by these jurisdictions poses serious interoperability challenges and hinders information sharing in a multijurisdictional coalition. In this paper, we discuss interoperability challenges and proposed approaches to address these challenges. In particular, we discuss solutions based on common backbone technologies and several types of interoperability gateways. We illustrate the approach using several scenarios. We are testing some of these scenarios in our lab.
Translational Gaps in Animal Models of Human Infusion Reactions to Nanomedicines (2018)

Adverse infusion reactions to regulatory approved nanomedicines in human subjects are idiosyncratic, but outwardly reproducible in pigs. A large body of evidence suggests that the porcine reactions are related to robust nanoparticle clearance by pulmonary intravascular macrophages (PIMs), and rapid release of arachidonate metabolites from these cells. Similar to pigs, other animals that have resident PIMs in their lungs also respond to intravenously injected particles, where rapid particle clearance by PIMs correlate with peak periods of cardiopulmonary distress. Normal human lungs, however, do not have PIMs, but 'induced' PIMs have been identified in pulmonary circulation under certain pathological conditions. We question suitability, and limitation of these preclinical models for global assessment of nanomedicine safety, and discuss alternative models and approaches.