gebhart/patrepeval huggingface dataset:
(Invited) Electrical Activity of Extended Defects in III-V Semiconductors (2019)

This paper gives an overview on the electrical activity of extended defects in III-V materials, combining different analysis methods, which are based on lifetime extraction from diode current-voltage characteristics and deep-level studies using Deep-Level Transient Spectroscopy (DLTS). To that purpose p+n junction diodes have been fabricated in In0.53Ga0.47As hetero-epitaxial layers on semi-insulating InP or GaAs substrates. By depositing a strained buffer layer, the Extended Defect Density (EDD) can be varied over several decades, enabling the study of the electrical impact in the same range. It will be shown that the generation and recombination (GR) lifetimes of the In0.53Ga0.47As layers become dominated by the EDs for densities above about 3×106 cm-2, whereby the dominant GR level moves closer to the mid gap position. This is supported by DLTS, showing the occurrence of specific electron traps for defective epi layers, which exhibit a capture behavior which is typical for extended defects.
Wells, Sub‐Collectors and ESD (2004)

This chapter contains sections titled: Diffused Wells Retrograde and Vertically Modulated Wells Triple-well and Isolated MOSFETs Ballast Resistors Sub-collectors Problems References
Electron-induced limitation of surface plasmon propagation in silver nanowires (2013)

Plasmonic circuitry is considered as a promising solution-effective technology for miniaturizing and integrating the next generation of optical nano-devices. A key element is the shared metal network between electrical and optical information enabling an efficient hetero-integration of an electronic control layer and a plasmonic data link. Here, we investigate to what extent surface plasmons and current-carrying electrons interfere in such a shared circuitry. By synchronously recording surface plasmon propagation and electrical output characteristics of individual chemically-synthesized silver nanowires we determine the limiting factors hindering the co-propagation of an electrical current and a surface plasmon in these nanoscale circuits.
Automated and secure IPv6 configuration in enterprise networks (2010)

Over the last decade, IPv6 has established itself as the most mature network protocol for the future Internet. Its recent deployment in core networks of operators, its availability to end customers of multiple ISPs together with the availability of native access to large services like Google assess the increasing penetration of IPv6. While its deployment from the inside of the network leading to the edges is successful, the transition remains an issue today for many enterprises which see it as a tedious and error prone task for network administrators. To fill this gap, we present the necessary algorithms and provide the supporting tools to enable this transition to become automatic. Based on a model of an IPv4 network, we describe the algorithms to build an optimized IPv6 adressing scheme and to automatically generate the adequate security plan as well as the corresponding configurations for the different devices in the network.
The capacity of the uniform noise rewritable channel with average cost (2010)

We present a closed form expression for the capacity of the uniform noise rewritable channel with average write cost and a constraint on the input range. We show the existence of a critical cost κ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> such that for all costs κ ≥ κ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> , the capacity/cost tradeoff is given by an offset added to the logarithm of the cost. Assuming κ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> > 1, for 1 ≤ κ <; κ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> the capacity/cost tradeoff grows faster than a logarithm.
Comparison of Therapeutic Effects between Pulsed and Continuous Wave 810-nm Wavelength Laser Irradiation for Traumatic Brain Injury in Mice (2011)

The therapeutic effect of LLLT for TBI with an 810-nm laser was more effective at 10-Hz pulse frequency than at CW and 100-Hz. This finding may provide a new insight into biological mechanisms of LLLT.
68Ga-P15-041, A Novel Bone Imaging Agent for Diagnosis of Bone Metastases (2021)

<sup>68</sup>Ga-P15-041 PET/CT, offering a rapid bone scan and high contrast images in minutes, is superior to the current method of choice in detecting bone metastases. It is reasonable to suggest that <sup>68</sup>Ga-P15-041 PET/CT could become a valuable routine nuclear medicine procedure in providing excellent images for detecting bone metastases in cancer patients. <sup>68</sup>Ga-P15-041 could become a valuable addition expanding the collection of <sup>68</sup>Ga-based routine nuclear medicine procedures where <sup>18</sup>F fluoride is not currently available.
Supplementary Literature from Genetic Alterations in the Tyrosine Kinase Transcriptome of Human Cancer Cell Lines (2023)

Supplementary Literature from Genetic Alterations in the Tyrosine Kinase Transcriptome of Human Cancer Cell Lines
Real-time diagnosis and prognosis with sensors of uncertain quality (2004)

This work presents a real-time approach to the detection, isolation, and prediction of component failures in large-scale systems through the combination of two modules. The modules themselves are then used in conjunction with an inference engine, TEAMS-RT, which is part of Qualtech Systems integrated diagnostic toolset, to provide the end user with accurate diagnostic and prognostic information about the state of the system. The first module is a filter used to "clean" observed test results from multiple sensors from system noise. The sensors have false alarm and missed detection probabilities that are not known a-priori, and must be estimated - ideally along with the accuracies of these estimates - online, within the inference engine. Further, recognizing a practical concern in most real systems, a sparsely instantiated observation vector must not be problematic. Multiple hypothesis tracking (MHT) is at the heart of the filtering algorithm and beta prior distributions are applied to the sensor errors. The second module is a prognostic engine that uses an interacting multiple model (IMM) approach to track the "trajectory" of degrading sensors. Kalman filters estimate the movement in each dimension of the sensors. The current state and trajectory of each sensor is then used to predict the time to failure value, i.e., when the component corresponding to the sensor is no longer usable. The modules are integrated together and as part of the TEAMS-RT suite; logic is presented for the cases that they disagree.
Material Properties of Si-Ge/Ge Quantum Wells (2008)

Germanium (Ge) and silicon-germanium (Si-Ge) have the potential to integrate optics with Si IC technology. The quantum-confined Stark effect, a strong electroabsorption mechanism often observed in III-V quantum wells (QWs), has been demonstrated in Si-Ge/Ge QWs, allowing optoelectronic modulators in such group IV materials. Here, based on photocurrent electroabsorption experiments on different samples and fitting of the resulting allowed and nominally forbidden transitions, we propose more accurate values for key parameters such as effective masses and band offsets that are required for device design. Tunneling resonance modeling including conduction band nonparabolicity was used to fit the results with good consistency between the experiments and the fitted transitions.
Genetics of primary lateral sclerosis (2020)

With the exception of rare, juvenile-onset, autosomal recessive cases, primary lateral sclerosis (PLS) has long been considered an exclusively sporadic motor neuron disease. However, the identification of PLS cases within pedigrees with familial amyotrophic lateral sclerosis (ALS), together with the clinical and neuropathological overlap with other neurodegenerative disease with strong genetic component such as ALS and hereditary spastic paraparesis (HSP), suggest the existence of a genetic component in PLS as well. Here we will review the genetics of juvenile PLS-like syndromes and the contribution of mutations in ALS and HSP-associated genes to PLS pathogenesis.
Synthesis and Insecticidal Activity of Spinosyn Analogs Functionally Altered at the 2'-, 3'- and 4'-Positions of the Rhamnose Moiety. (2000)

In an effort to increase the insecticidal activity of the spinosyn family of naturally occurring macrolides, the 2'-, 3'- and 4'-O-desmethyl-O-acetyl analogs and the 2'-, 3'-, and 4'-O-desmethoxy analogs have been synthesized. These analogs were prepared synthetically from the minor spinosyn factors H, J, K, L and Q either via direct acylation of the corresponding factor or deoxygenation of an intermediate xanthate. The acylated analogs were all more potent insecticides against Heliothis virescens larvae than their respective parent factors, but not as potent as spinosyns A or D. The deoxy analogs were also more potent insecticides than their respective parent factors. The 2'-desmethoxy analogs showed, for the first time, analogs with insecticidal potency against H. virescens greater than that of spinosyns A and D, indicating that polarity is not well tolerated in the rhamnose moiety of spinosyn A.
Primary Non-Hodgkin's Lymphoma of the Lung Presenting as Bronchiolitis Obliterans Organizing Pneumonia (1997)

A 44-year-old man presented with fever, dyspnea, and bilateral cavitary lung lesions. Following percutaneous transthoracic CT guided needle biopsy of the lung, a diagnosis of bronchiolitis obliterans organizing pneumonia (BOOP) was made and the patient was treated with corticosteroids. Despite a good initial response he developed new lung lesions within six months, associated with a lack of response to corticosteroids. Due to further deterioration and the development of Guillian-Barre' syndrome an open lung biopsy was performed and revealed T-cell rich, B-cell non Hodgkin's lymphoma with BOOP. We suggest that BOOP may be the presenting manifestation of primary lung lymphoma. We recommend that when BOOP has an atypical course or does not respond to corticosteroids open lung biopsy should be performed in order to exclude pulmonary lymphoma.
Human Immunodeficiency Virus Tat Protein Aids V Region Somatic Hypermutation in Human B Cells (2018)

Long-term survivors of human immunodeficiency virus (HIV) infection have been shown to have a greatly increased incidence of B cell lymphomas. This increased lymphomagenesis suggests some link between HIV infection and the destabilization of the host B cell genome, a phenomenon also suggested by the extraordinary high frequency of mutation, insertion, and deletion in the broadly neutralizing HIV antibodies. Since HIV does not infect B cells, the molecular mechanisms of this genomic instability remain to be fully defined. Here, we demonstrate that the cell membrane-permeable HIV Tat proteins enhance activation-induced deaminase (AID)-mediated somatic hypermutation (SHM) of antibody V regions through their modulation of the endogenous polymerase II (Pol II) transcriptional process. Extremely small amounts of Tat that could come from bystander HIV-infected cells were sufficient to promote SHM. Our data suggest HIV Tat is one missing link between HIV infection and the overall B cell genomic instability in AIDS patients.<b>IMPORTANCE</b> Although the introduction of antiretroviral therapy (ART) has successfully controlled primary effects of human immunodeficiency virus (HIV) infection, such as HIV proliferation and HIV-induced immune deficiency, it did not eliminate the increased susceptibility of HIV-infected patients to B cell lymphomas. We find that a secreted HIV protein, Tat, enhances the intrinsic antibody diversification mechanism by increasing the AID-induced somatic mutations at the heavy-chain variable (VH) regions in human B cells. This could contribute to the high rate of mutation in the variable regions of broadly neutralizing anti-HIV antibodies and the genomewide mutations leading to B cell malignancies in HIV carriers.
Mixed ionic-electronic conductor-based radiation detectors and methods of fabrication (2023)

A method of fabricating a mixed ionic-electronic conductor (e.g. TlBr)-based radiation detector having halide-treated surfaces and associated methods of fabrication, which controls polarization of the mixed ionic-electronic MIEC material to improve stability and operational lifetime.
Improving orthogonal space-time block codes by utilizing quantized feedback information (2002)

We propose a transmission scheme which utilizes vector quantized channel information obtained from a feedback link for improving a space-time code. The result is a transmission method which provides robustness to the non-perfect nature of the channel information while combining the benefits of conventional beamforming with those given by space-time coding.
Appendix B - Some Subtleties in Dealing with Mathematica Images (2022)

In the chapters of this book, we have often had occasion to use the Mathematica commands <strong>Image[]</strong> and <strong>ImageData[]</strong> when moving between numerical data and images. Given an array of real numbers, an image can be obtained by using the command <strong>Image[</strong><i>array</i><strong>]</strong>, while to go in the opposite direction, from an image to real numbers, the command <strong>ImageData[</strong><i>image</i><strong>]</strong> is used. There are some peculiarities of these commands that we wish to point out here.
The Effect of Clay Content on the Spin–Spin NMR Relaxation Time Measured in Porous Media (2020)

Clays, hydrous aluminous phyllosilicates, have a significant impact on the interpretation of physical measurements and properties of porous media. In particular, the presence of paramagnetic and/or ferromagnetic ions like iron, nickel, and magnesium in clays can complicate the analysis of nuclear magnetic resonance (NMR) data for porous media characterization. This is due to the internal magnetic field gradient induced by the clay minerals. In this study, we aim to investigate the impact of clay content on spin-spin relaxation time (<i>T</i> <sub>2</sub>), which is strongly influenced by the pore surface chemistry. Seven rock core plugs, characterized with variable clay content, were used for this purpose. The clay mineralogy and volume were determined by means of quantitative evaluation of minerals by scanning electron microscopy (QEMSCAN). The <i>T</i> <sub>2</sub> relaxation time was measured using a Carr-Purcell-Meiboom-Gill (CPMG) sequence with variable echo spacing (<i>T</i> <sub>E</sub>). The maximum percentage difference in dominant <i>T</i> <sub>2</sub> values (MRD<i>T</i> <sub>2</sub>) between shortest and longest echo spacing was subsequently correlated with clay content obtained from QEMSCAN. Our results show that the reduction in <i>T</i> <sub>2</sub> distribution with increasing echo time <i>T</i> <sub>E</sub> is more significant in samples characterized by higher clay contents. The MRD<i>T</i> <sub>2</sub> was found to be strongly correlated with clay content. An analytical equation is presented expressing MRD<i>T</i> <sub>2</sub> as a function of clay content providing a quick and non-destructive approach for clay content estimation. Moreover, the MRD<i>T</i> <sub>2</sub>-clay content relationship showed a nonlinear behavior: MRD<i>T</i> <sub>2</sub> increases drastically as the clay content increases up to 15%, beyond which the rate of MRD<i>T</i> <sub>2</sub> change with clay content diminishes. This behavior could be attributed to the clay distribution. At higher clay contents (above 15%), it is more likely for clay to form clusters (structural clays), which will not significantly increase the clay surface in contact with the pore fluid. Further, experimental data suggests that ignoring the impact of clay on internal magnetic gradients and <i>T</i> <sub>2</sub> signal may result in considerable underestimation of the actual pore size distribution.
A co-designed wideband circularly polarized integrated filtering antenna (2015)

In this paper, we report the design, fabrication, and experimental measurement of a compact co-designed circularly polarized (CP) filtering antenna with a wide operational bandwidth. In the filtering antenna module, the radiator serves simultaneously as the last resonator of the filter which was realized by coupled stripline open-loop resonators. A proof-of-concept design is presented with both its S <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">11</sub> <; -14 dB and axial ratio <; 3 dB bandwidths covering 12.5%, ranging from 3.75 to 4.25 GHz. A prototype was fabricated and characterized, showing strong agreement between simulated and measured results. The gain response exhibits a profile similar to the transmission of a bandpass filter. The integrated filtering and radiating modules with a compact form factor and improved performance metric are expected to find potential applications in a variety of wireless communication systems.
Correction to: In Vivo Delivery of Nucleic Acid-Encoded Monoclonal Antibodies (2020)

The article In Vivo Delivery of Nucleic Acid-Encoded Monoclonal Antibodies, written by Ami Patel, Mamadou A. Bah and David B.
Fetal Alz-50 Clone 1 Interacts with the Human Orthologue of the Kelch-like Ech-Associated Protein (2004)

The fetal Alz-50 reactive clone 1 (FAC1) protein exhibits altered expression and subcellular localization during neuronal development and neurodegenerative diseases such as Alzheimer's disease. Using the yeast two-hybrid screen, the human orthologue of Keap1 (hKeap1) was identified as a FAC1 interacting protein. Keap1 is an important regulator of the oxidative stress response pathway through its interaction with the Nrf family of transcription factors. An interaction between full-length FAC1 and hKeap1 proteins has been demonstrated, and the FAC1 binding domain of hKeap1 has been identified as the Kelch repeats. In addition, FAC1 colocalizes with endogenous Keap1 within the cytoplasm of PT67 cells. Exogenously introduced eGFP:hKeap1 fusion protein redistributed FAC1 to colocalize with eGFP:hKeap1 in perinuclear, spherical structures. The interaction between FAC1 and hKeap1 is reduced by competition with the Nrf2 protein. However, competition by Nrf2 for hKeap1 is reduced by diethylmaleate (DEM), a known disrupter of the Nrf2:Keap1 interaction. DEM does not affect the ability of FAC1 to bind hKeap1 in our assay. These results suggest that hKeap1 regulates FAC1 in addition to its known role in control of Nrf2. Furthermore, the observed competition between FAC1 and Nrf2 for binding hKeap1 indicates that the interplay between these three proteins has important implications for neuronal response to oxidative stress.
Synthetic induction of immunogenic cell death by genetic stimulation of endoplasmic reticulum stress (2014)

<i>Cis</i>-diamminedichloridoplatinum(II) (CDDP), commonly referred to as cisplatin, is a chemotherapeutic drug used for the treatment of a wide range of solid cancers. CDDP is a relatively poor inducer of immunogenic cell death (ICD), a cell death modality that converts dying cells into a tumor vaccine, stimulating an immune response against residual cancer cells that permits long-lasting immunity and a corresponding reduction in tumor growth. The incapacity of CDDP to trigger ICD is at least partially due to its failure to stimulate the premortem endoplasmic reticulum (ER)-stress response required for the externalization of the "eat-me" signal calreticulin (CRT) on the surface of dying cancer cells. Here, we developed a murine cancer cell line genetically modified to express the ER resident protein reticulon-1c (Rtn-1c) by virtue of tetracycline induction and showed that enforced Rtn-1c expression combined with CDDP treatment promoted CRT externalization to the surface of cancer cells. In contrast to single agent treatments, the tetracycline-mediated Rtn-1c induction combined with CDDP chemotherapy stimulated ICD as measured by the capacity of dying tumor cells, inoculated into syngenic immunocompetent mice, to mount an immune response to tumor re-challenge 1 week later. More importantly, established tumors, forced to constitutively express Rtn-1c in vivo by continuous treatment with tetracycline, became responsive to CDDP and exhibited a corresponding reduction in the rate of tumor growth. The combined therapeutic effects of Rtn-1c induction with CDDP treatment was only detected in the context of an intact immune system and not in <i>nu/nu</i> mice lacking thymus-dependent T lymphocytes. Altogether, these results indicate that the artificial or "synthetic" induction of immunogenic cell death by genetic manipulation of the ER-stress response can improve the efficacy of chemotherapy with CDDP by stimulating anticancer immunity.
Consideration of hydrophobic attractions in end-to-end cyclization (1989)

This work was supported by the NSF-MRL Program through the Center for Materials Research at Stanford University.
Touch, Strike, Slide, Twist, Shudder (2020)

This video catches Bowers and Hagan in the act of sticking their dirty hands into machineries best left alone as they struggle in the midst of unruly sonic behaviours and non-obvious interaction design. Using synthesis algorithms with extreme sensitivity to gesture, they steer rather than control a complex solfége of pulses, noises, crackles and drones, negotiating a link between chaotic dynamics and improvisation. All relationships are tricky, especially the love polyhedron between Bowers, Hagan, their interfaces, their algorithms and their many noises. But we hope for the best.
Achieving Superplasticity of UltrafineGrained RodLike AZ61 Alloy Using HighPressure Sliding (2016)

Recent study demonstrated that processing through HighPressure Sliding (HPS) is effective for grain refinement of a rod like A2024 aluminum alloy. In this study, the HPS processing was applied to an AZ61 magnesium alloy. To achieve homogeneous grain refinement throughout the cross section of the rods, the samples were rotated around the longitudinal axis of the rod every after HPS processing. Microstructural observations revealed that the grain size was refined to 450 nm. Tensile tests showed that the samples exhibited excellent superplasticity with a maximum elongation of 1140 at a testing temperature of 473 K and at an initial strain rate of 1.0×10-3 s-1, giving a strain rate sensitivity of 0.4. [doi:10.2320/jinstmet.J2015046]
Genetic Mapping Studies of Familial Juvenile Hyperuricemic Nephropathy on Chromosome 16p11-p13 (2003)

Familial juvenile hyperuricemic nephropathy (FJHN), which is inherited as an autosomal dominant disorder, is characterized by hyperuricemia, a low fractional renal excretion of urate, and chronic renal failure that is associated with interstitial fibrosis. Studies in 4 families (3 European and 1 Japanese) have mapped the gene causing autosomal dominant FJHN to chromosome 16p11-p13. To refine this location we have pursued linkage studies in 7 European families with autosomal dominant FJHN and used 11 chromosome 16p11-p13 polymorphic loci whose order has been established as 16pter-D16S3069-D16S3060-D16S3041-D16S3036-D16S3046-[D16S403,D16S417]-D16S420-D16S3113-D16S401-D16S3133-16cen. Cosegregation between these polymorphic loci and FJHN was observed in 5 of the families, and linkage was established between FJHN and 6 loci (peak LOD score, 5.32 with D16S417, at 0% recombination), with the most likely location of FJHN being within a 22-centimorgan interval flanked centromerically by D16S401 and telomerically by D16S3069. Furthermore, FJHN in 2 families was found not to be linked to chromosome 16p11-p13, thereby demonstrating genetic heterogeneity. Thus, 5 additional families with FJHN showing linkage to chromosome 16p11-p13 loci have been identified, and genetic heterogeneity has been demonstrated in more than 25% of FJHN families. These results will facilitate the characterization of this gene regulating urate metabolism.