gebhart/patrepeval huggingface dataset:
Transformation of the Chromium Coordination Environment in LaCrAsO Induced by Hydride Doping: Formation of La2Cr2As2OyHx (2017)

We report the synthesis of La<sub>2</sub>Cr<sub>2</sub>As<sub>2</sub>O<sub>y</sub>H<sub>x</sub> (0.1 < y < 1.6) oxyhydride solid solutions using a solid-state reaction under high pressure with a solid-state hydrogen source and exhibit an example of how H<sup>-</sup> doping can also promote structural changes: H<sup>-</sup> doping in LaCrAsO results in the formation of La<sub>2</sub>Cr<sub>2</sub>As<sub>2</sub>O<sub>y</sub>H<sub>x</sub> with the La<sub>2</sub>Fe<sub>2</sub>Se<sub>2</sub>O<sub>3</sub>-type layered structure. Remarkably, this transformation includes a change of the coordination number of Cr from 4 to 6, with the some of the H<sup>-</sup> being accommodated in new sites within the CrAs layers. In this way, H<sup>-</sup> not only serves as a conventional electron dopant by the substitution of O<sup>2-</sup> but also makes new bonds to the transition metals.
"Ab initio" studies of hydrogen-enhanced oxygen diffusion in silicon (1999)

A novel microscopic mechanism for hydrogen-enhanced oxygen diffusion in p-doped silicon is proposed. A path for joint diffusion of O and H is obtained from an ab-initio molecular dynamics "kick" simulation. The migration pathway consists of a two-step mechanism, with a maximum energy of 1.46 eV. This path represents a 0.54 eV reduction in the static barrier when compared with the diffusion of isolated O in Si, in excellent agreement with experiments.
Bioorthogonal Approach to Identify Unsuspected Drug Targets in Live Cells (2013)

A proteomics method to pull down secondary drug targets from live cells is described. The drug of interest is modified with trans-cyclooctene (TCO) and incubated with live cells. Upon cell lysis, the modified drug bound to the protein is pulled down using magnetic beads decorated with a cleavable tetrazine-modified linker. Samples are then run on an SDS-PAGE gel and isolated bands are submitted for mass spectrometry analysis to identify drug targets.
Analysis and Improvement of Impedance Balancing Technique for Common Mode Noise Mitigation (2020)

As an effective method to reduce the Common Mode (CM) Electromagnetic Interference (EMI) noise, the impedance balancing technique is utilized in different converters. In theory, this balancing technique could reduce the noise to zero. However, the practical result is not stable and suffered from challenges like the noise peak at high frequency. Based on a conventional boost converter, this paper introduces an accurate noise modeling method by identifying the noise source and propagation paths. The influence of high-frequency voltage ringing is also taken into consideration to improve the accuracy of this noise model. Then the modeling method is utilized to analyze the impedance balancing technique. Based on the noise expressions and the impedance information, the degree of noise source attenuation is investigated properly. In addition, this model helps to redesign the parameters of the balanced arms in quantitative. The optimized scheme improves performance effectively and avoids the noise peak problem. Experimental results are presented to demonstrate the feasibility and effectiveness of the proposed schemes.
PC Bond Cleavage of (silox)3NbPMe3 (silox = tBu3SiO) under Dihydrogen Leads to (silox)3NbCH2, (silox)3NbPH or (silox)3NbP(H)Nb(silox)3, and CH4 (2006)

Photolysis of the equilibrium mixture (silox)3NbPMe3 (1) + H2 (1-3 atm) right arrow over left arrow (silox)3Nb(Heq)2 (2e, tbp)/(silox)3Nb(Ht)2 (2t, pseudo-Td) + PMe3 causes PC bond cleavage. Depending on conditions, various amounts of (silox)3Nb=CH2 (3), (silox)3Nb=PH (5-H), (silox)3Nb=PMe (5-Me), (silox)3Nb=P(H)Nb(silox)3 (9, precipitated if N2 is present; X-ray), (silox)3NbH (4, active only through equilibration with 2e,t), and CH4 are produced. Addition of PH3 to 1 provides an independent route to 5-H; its deprotonation gives [(silox)3NbP]Li (6), whose methylation yields 5-Me. Early conversion 3:5-H ratios of approximately 3:1 suggest that initial PC bond activation is slow relative to subsequent PC bond cleavages. Addition of HPMe2 and H2PMe to 1 generates (silox)3HNbPMe2 (7) and (silox)3HNbPHMe (8), respectively, and both degrade faster than PMe3. A mechanism based around sequential PC or CH oxidative addition, followed by 1,2-elimination events, is proposed. The limiting step in the decomposition of all PMe3 is a slow hydrogenation of 3 to regenerate 2e,t and produces CH4. Hydrides 2e,t are likely to be the photolytically active species.
DEK binding to class II MHC Y-box sequences is gene- and allele-specific (2003)

Using electrophoretic mobility shift assays, we examined sequence-specific binding of DEK, a potential autoantigen in juvenile rheumatoid arthritis, to conserved Y-box regulatory sequences in class II MHC gene promoters. Nuclear extracts from several cell lines of different phenotypes contained sequence-specific binding activity recognizing DRA, DQA1*0101, and DQA1*0501 Y-box sequences. Participation of both DEK and NF-Y in the DQA1 Y-box binding complex was confirmed by 'supershifting' with anti-DEK and anti-NF-Y antibodies. Recombinant DEK also bound specifically to the DQA1*0101 Y box and to the polymorphic DQA1*0501 Y box, but not to the consensus DRA Y box. Measurement of the apparent dissociation constants demonstrated a two- to fivefold difference in DEK binding to the DQA1 Y-box sequence in comparison with other class II MHC Y-box sequences. Residues that are crucial for DEK binding to the DQA1*0101 Y box were identified by DNase I footprinting. The specific characteristics of DEK binding to these related sequences suggests a potential role for DEK in differential regulation of class II MHC expression, and thus in the pathogenesis of juvenile rheumatoid arthritis and other autoimmune diseases.
Correction of the Enzymatic and Functional Deficits in a Model of Pompe Disease Using Adeno-associated Virus Vectors (2002)

Pompe disease is a lysosomal storage disease caused by the absence of acid alpha-1,4 glucosidase (GAA). The pathophysiology of Pompe disease includes generalized myopathy of both cardiac and skeletal muscle. We sought to use recombinant adeno-associated virus (rAAV) vectors to deliver functional GAA genes in vitro and in vivo. Myotubes and fibroblasts from Pompe patients were transduced in vitro with rAAV2-GAA. At 14 days postinfection, GAA activities were at least fourfold higher than in their respective untransduced controls, with a 10-fold increase observed in GAA-deficient myotubes. BALB/c and Gaa(-/-) mice were also treated with rAAV vectors. Persistent expression of vector-derived human GAA was observed in BALB/c mice up to 6 months after treatment. In Gaa(-/-) mice, intramuscular and intramyocardial delivery of rAAV2-Gaa (carrying the mouse Gaa cDNA) resulted in near-normal enzyme activities. Skeletal muscle contractility was partially restored in the soleus muscles of treated Gaa(-/-) mice, indicating the potential for vector-mediated restoration of both enzymatic activity and muscle function. Furthermore, intramuscular treatment with a recombinant AAV serotype 1 vector (rAAV1-Gaa) led to nearly eight times normal enzymatic activity in Gaa(-/-) mice, with concomitant glycogen clearance as assessed in vitro and by proton magnetic resonance spectroscopy.
In vivo anti-inflammatory and anti-platelet aggregation activities of longissiminone A, isolated from Usnea longissima. (2017)

Secondary metabolite, longissiminone A (1) was isolated from a lichen, Usnea longissima. It was screened for its' in vivo anti-inflammatroy and anti-platelet aggregation activities. Compound 1 showed moderate in vivo anti-inflammatory activity as well as moderately active against the aggregation induced by arachidonic acid at different doses.
Effect of Copper Ion Concentration on Bacteria and Cells (2019)

In the oral cavity, dental implants—most often made of commercially pure titanium—come in contact with bacteria, and antibacterial management has been researched extensively to improve patient care. With antibiotic resistance becoming increasingly prevalent, this has resulted in copper being investigated as an antibacterial element in alloys. In this study, the objective was to investigate the copper ion concentrations at which cyto-toxicity is avoided while bacterial inhibition is ensured, by comparing Cu ion effects on selected eukaryotes and prokaryotes. To determine relevant copper ion concentrations, ion release rates from copper and a 10 wt. % Cu Ti-alloy were investigated. Survival studies were performed on MC3T3 cells and Staphylococcus epidermidis bacteria, after exposure to Cu ions concentrations ranging from 9 × 10−3 to 9 × 10−12 g/mL. Cell survival increased from &lt;10% to &gt;90% after 24 h of exposure, by reducing Cu concentrations from 9 × 10−5 to 9 × 10−6 g/mL. Survival of bacteria also increased in the same range of Cu concentrations. The maximum bacteria growth was found at 9 × 10−7 g/mL, probably due to stress response. In conclusion, the minimum inhibitory concentrations of Cu ions for these prokaryotes and eukaryotes were found in the range from 9 × 10−5 to 9 × 10−6 g/mL. Interestingly, the Cu ion concentration correlating to the release rate of the 10 wt. % Cu alloy (9 × 10−8 g/mL) did not kill the bacteria, although this alloy has previously been found to be antibacterial. Further studies should investigate in depth the bacteria-killing mechanism of copper.
Measurement of the longitudinal diffusion of ionization electrons in the MicroBooNE detector (2021)

Abstract Accurate knowledge of electron transport properties is vital to understanding the information provided by liquid argon time projection chambers (LArTPCs). Ionization electron drift-lifetime, local electric field distortions caused by positive ion accumulation, and electron diffusion can all significantly impact the measured signal waveforms. This paper presents a measurement of the effective longitudinal electron diffusion coefficient, D L , in MicroBooNE at the nominal electric field strength of 273.9 V/cm. Historically, this measurement has been made in LArTPC prototype detectors. This represents the first measurement in a large-scale (85 tonne active volume) LArTPC operating in a neutrino beam. This is the largest dataset ever used for this measurement. Using a sample of ∼70,000 through-going cosmic ray muon tracks tagged with MicroBooNE's cosmic ray tagger system, we measure D L = 3.74 +0.28 -0.29 cm 2 /s.
Magnetic nanoparticle ink for RF integrated inductor applications (2014)

For the first time, a magnetic ink containing permalloy nanoparticles coated with a polyelectrolyte shell is presented for miniaturization of radio frequency (RF) integrated inductors. Coating permalloy particles with an electrolyte polymer provides particle separation which minimizes eddy current losses. Coated particles are incorporated into a viscous ink to enable precise deposition. This magnetic ink is integrated with a single-turn planar inductor. Measurements show a 40% inductance enhancement at GHz frequencies, a peak quality factor of 7.1, and a self-resonant frequency of 4.84 GHz. When compared with recent literature, this method shows promise for reducing the size of RF passives.
When genome editing goes off-target (2019)

Detecting unintended mutations could improve DNA-editing strategies
2P096 Molecular characterization of prefoldins from a hyperthermophilic archaeon, Thermococcus sp. strain KS-1(31. Protein folding and misfolding (II),Poster Session,Abstract,Meeting Program of EABS & BSJ 2006) (2006)

Tu im'estigate effects of hydrationXdehydratien on protein folding. we fo11owcd
80-Gbit/s DQPSK Optical Tapped-Delay-Line Equalization using Finely Tunable Delays, Phases and Amplitudes (2011)

We experimentally demonstrate a tunable and reconfigurable optical tapped delay line using conversion dispersion based delays with optical multicasting and multiplexing. After equalization, at BER of 10-9 and 3 dB power penalty, dispersion tolerance is improved by &gt;50% and 200% for 80-Gbit/s RZ-DQPSK and 40-Gbit/s RZ-DPSK signals, respectively.
ChemInform Abstract: Protease‐Catalyzed Kinetically Controlled Peptide Synthesis (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Epitaxial BaTiO3/MgO Structure Grown on GaAs(100) by Pulsed Laser Deposition* (1993)

BaTiO 3 thin films on MgO encapsulated GaAs(100) were prepared epitaxially, in condition ranging from 600°C to 800°C and from 2×10 -4 Torr O 2 to 1×10 -2 Torr O 2 , by pulsed laser deposition. The epitaxial relationship between all materials was cube-on-cube. BaTiO 3 thin films obtained were c axis oriented tetragonal phase and showed ferroelectric properties. Epitaxial BaTiO 3 had quite smooth surface of less than 100 Å in roughness. BaTiO 3 grown on 40-Å-thick epitaxial MgO was also epitaxial although defect density in BaTiO 3 looked higher than that in BaTiO 3 grown on 400-Å-thick MgO. The interfaces of BaTiO 3 /40-Å-thick MgO/GaAs structure were abrupt and free of secondary phases in spite of the quite thin MgO layer.
Glutamine Deprivation Inhibits Invasion of Human Prostate Carcinoma LnCap Cells through Inactivation of Matrix Metalloproteinases and Modulation of Tight Junctions (2013)

암세포를 포함한 생체 내 빠른 분열을 요구하는 세포 집단에서 세포 내 구성요소 및 에너지원으로서 글루타민의 요구량이 증대되지만, 종양세포의 글루타민 의존적 대사작용에 관한 기전은 여전히 잘 알려진 바 없다. 본 연구에서는 LnCaP 전립선 암세포의 이동성 및 침윤성에 미치는 글루타민 결핍효능을 조사하였다. 본 연구의 결과에 의하면 LnCaP 세포에서 글루타민 결핍에 의하여 세포의 이동성 및 세포의 침윤성이 현저하게 억제되었으며, 이러한 이동성 및 침윤성 억제는 TIMPs의 발현 증대에 의한 MMPs의 발현 감소 및 그들의 효소적 활성 저하와 연관성이 있었다. 또한 글루타민이 결핍된 조건에서 배양된 LnCaP 세포에서 TER의 현저한 증가가 관찰되었는데, 이는 TJs의 조절인자인 claudin family 발현의 차단에 의한 것으로 생각되어진다. 본 연구의 결과에 의하면 암세포의 증식에서 글루타민의 결핍은 TJ의 결합력 증대와 MMPs의 활성을 저하시킴으로써 암세포 전이에 가장 기본적인 과정인 암세포의 이동성과 침윤성을 억제시킬 수 있을 것으로 생각된다.
The relationship of the factor V Leiden mutation or the deletion-deletion polymorphism of the angiotensin converting enzyme to postoperative thromboembolic events following total joint arthroplasty (2001)

Our results suggest that neither of these potentially hypercoaguable states are associated with an increased risk of symptomatic thromboembolic events following total hip or knee arthroplasty in patients receiving pharmacological thromboprophylaxis.
THz Band Channel Measurements and Statistical Modeling for Urban D2D Environments (2022)

THz band is envisioned to be used in 6G systems to meet the ever-increasing demand for data rate. However, before an eventual system design and deployment can proceed, detailed channel sounding measurements are required to understand key channel characteristics. In this paper, we present a first extensive set of channel measurements for urban outdoor environments that are ultra-wideband, and double-directional where both transmitter and receiver are at the same height. In all, we present measurements at 38 locations, consisting of nearly 50,000 impulse responses, representing both line-of-sight (LoS) and non-line-of-sight (NLoS) cases in the 1-100 m range between 145-146 GHz. We provide modeling for path loss, shadowing, delay spread, angular spread, multipath component (MPC) power distribution and Qtapnumber. We find, among other things, that outdoor communication over tens of meters is feasible in this frequency range even in NLoS scenarios, that omni-directional delay spreads of up to 100 ns, and directional delay spreads of up to 10 ns are observed, while angular spreads are also quite significant, and a surprisingly large number of MPCs are observed for 1 GHz bandwidth and 13° beamwidth. These results constitute an important first step towards better understanding the wireless channel in the THz band.
Characteristics of Renal Handling of Human Light Chain by the Perfused Rat Kidney (1978)

Conference Abstract| February 01 1978 Characteristics of Renal Handling of Human Light Chain by the Perfused Rat Kidney J. F. Falconer Smith; J. F. Falconer Smith 1Nuffield Department of Clinical Biochemistry and Gibson Laboratories, Radcliffe Infirmary, Oxford Search for other works by this author on: This Site PubMed Google Scholar R. I. van Hegan; R. I. van Hegan 1Nuffield Department of Clinical Biochemistry and Gibson Laboratories, Radcliffe Infirmary, Oxford Search for other works by this author on: This Site PubMed Google Scholar M. P. Esnouf; M. P. Esnouf 1Nuffield Department of Clinical Biochemistry and Gibson Laboratories, Radcliffe Infirmary, Oxford Search for other works by this author on: This Site PubMed Google Scholar B. D. Ross B. D. Ross 1Nuffield Department of Clinical Biochemistry and Gibson Laboratories, Radcliffe Infirmary, Oxford Search for other works by this author on: This Site PubMed Google Scholar Clin Sci Mol Med (1978) 54 (2): 3P. https://doi.org/10.1042/cs054003P Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter LinkedIn Cite Icon Cite Get Permissions Citation J. F. Falconer Smith, R. I. van Hegan, M. P. Esnouf, B. D. Ross; Characteristics of Renal Handling of Human Light Chain by the Perfused Rat Kidney. Clin Sci Mol Med 1 February 1978; 54 (2): 3P. doi: https://doi.org/10.1042/cs054003P Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsClinical Science Search Advanced Search This content is only available as a PDF. © 1978 The Biochemical Society and the Medical Research Society1978 Article PDF first page preview Close Modal You do not currently have access to this content.
Higher-order epistasis and phenotypic prediction (2020)

Abstract Contemporary high-throughput mutagenesis experiments are providing an increasingly detailed view of the complex patterns of genetic interaction that occur between multiple mutations within a single protein or regulatory element. By simultaneously measuring the effects of thousands of combinations of mutations, these experiments have revealed that the genotype-phenotype relationship typically reflects genetic interactions not only between pairs of sites, but also higher-order interactions among larger numbers of sites. However, modeling and understanding these higher-order interactions remains challenging. Here, we present a method for reconstructing sequence-to-function mappings from partially observed data that can accommodate all orders of genetic interaction. The main idea is to make predictions for unobserved genotypes that match the type and extent of epistasis found in the observed data. This information on the type and extent of epistasis can be extracted by considering how phenotypic correlations change as a function of mutational distance, which is equivalent to estimating the fraction of phenotypic variance due to each order of genetic interaction (additive, pairwise, three-way, etc.). Using these estimated variance components, we then define an empirical Bayes prior that in expectation matches the observed pattern of epistasis, and reconstruct the genotype-phenotype mapping by conducting Gaussian process regression under this prior. To demonstrate the power of this approach, we present an application to the antibody-binding domain GB1 and also provide a detailed exploration of a dataset consisting of high-throughput measurements for the splicing efficiency of human pre-mRNA 5 ′ splice sites, for which we also validate our model predictions via additional low-throughput experiments.
In-plant demonstration of a machnozzle as a fabric predrying device (1981)

Monthly status reports no. [1-6], and Final report, Project no. A-2776 (subproject is E-27-689/Carr/School of Textile Engineering
VeSPA Instruction Set (2004)

A summary is not available for this content so a preview has been provided. Please use the Get access link above for information on how to access this content.
Specifying preferences based on user history (2002)

Many applications require users to specify preferences. We support users in this task by letting them define preferences relative to their personal history or that of other users. We implement this idea using a graphical technique called control shadows, which we have implemented on both a desktop computer and on a cell phone with a small, grayscale display. An empirical study compared user performance on the graphical interface and a text table interface with identical functionality. On the desktop, users completed their tasks more quickly and effectively and strongly preferred the graphical interface. On the cell phone, there was no significant difference between the graphical and table interfaces. Finally, personal history proved useful in specifying preferences, but history of other users was not helpful
Foreign Object Detection (2017)

Due to strong and high-frequency magnetic field between transmitting (Tx) and receiving (Rx) coils of wireless stationary electric vehicle (EV) chargers, there is the possibility of them catching fire from debris of a metal piece in the magnetic field, which is inductively heated during charging. Position detection (POD) of misalignment between Tx and Rx is also needed to deliver maximum power at the optimum position. In this chapter, the FOD and POD are explained, introducing dual-purpose non-overlapped coil sets for both FOD and POD, which were invented by Chun T. Rim. Not only the existence of conductive object debris on a Tx coil but also the location of them are determined by an induced voltage difference of the coil sets. By measuring the induced voltage of the coil sets, displacements between a Tx coil and an Rx coil can also be found to inform drivers of their EV alignments. Moreover, the proposed FOD and POD devices do not arise from any power losses in inductive power transfer (IPT). The proposed non-overlapped coil sets have been demonstrated by simulations and experiments for a prototype coil set. Throughout the experiments, the induced voltage difference of a coil set shows 2.19 mV (ideally zero) without foreign objects while the induced voltage difference significantly increases by 78.2 mV, which is about 35 times that of the value without objects, when eight conductive coins are located on a Tx coil. Also it is found that POD can be achieved by measuring the variation of the induced voltages in coil sets when an Rx coil moves on a Tx coil. This chapter is based on the paper by M.R. Sonapreetha. S.Y. Jeong, S.Y. Choi, and C.T. Rim, “Dual-purpose non-overlapped coil sets as foreign object and vehicle location detections for wireless stationary EV Chargers,” in IEEE 2015 WoW, June 2015, pp. 1–7.
Calendar Aging Effect on the Open Circuit Voltage of Lithium-Ion Battery (2023)

In recent years, lithium-ion batteries (LiBs) have gained a lot of importance due to the increasing use of renewable energy sources and electric vehicles. To ensure that batteries work properly and limit their degradation, the battery management system needs accurate battery models capable of precisely predicting their parameters. Among them, the state of charge (SOC) estimation is one of the most important, as it enables the prediction of the battery’s available energy and prevents it from operating beyond its safety limits. A common method for SOC estimation involves utilizing the relationship between the state of charge and the open circuit voltage (OCV). On the other hand, the latter changes with battery aging. In a previous work, the authors studied a simple function to model the OCV curve, which was expressed as a function of the absolute state of discharge, q, instead of SOC. They also analyzed how the parameters of such a curve changed with the cycle aging. In the present work, a similar analysis was carried out considering the calendar aging effect. Three different LiB cells were stored at three different SOC levels (low, medium, and high levels) for around 1000 days, and an analysis of the change in the OCV-q curve model parameters with the calendar aging was performed.