gebhart/patrepeval huggingface dataset:
Study on vibration response characteristics of turbine blade for turbo-charger (2019)

In the mechanical design of a turbine blade for an automotive turbo-charger, it is pointed out that the mistuning effect caused by the difference of the casting condition should be considered. Namely, the difference of the casting condition causes the small variation of Young's modulus of each blade on a turbine wheel. These small variations break the cyclic symmetry, and split the eigenvalue pairs. In the forced response of a mistuned system, the responses of all blades become different, and the response of a certain blade may become extremely large due to splitting of the duplicated eigenvalues and distortion of the vibration modes. In this study, the reduced order model FMM (Fundamental Mistuning Model) is applied to evaluate the resonant response of mistuned system. First, the frequency response analysis of mistuned system is carried out, using both of the FMM and the direct FEM, and the calculated results are compared to confirm the validity of the FMM. Second, the frequency response analysis of mistuned system is carried out using the FMM, the Monte Carlo simulation and the optimal method to examine the effect of various parameters on the maximum response of a mistuned system. In addition, the effect of the intentional mistuning on the reduction of the maximum response is researched using the genetic algorithm.
Translating nutritional immunology into drug development for inflammatory bowel disease (2016)

Nutritional immunology and drug development research centered around immunoregulatory pathways can provide safer and more effective drugs while accelerating the path to cures.
CRF-41 Stimulates the Release of β-Lipotrophin and β-Endorphin in Normal Human Subjects (1984)

A prompt rise in circulating immunoreactive N- and C-terminal lipotrophin (LPH) accompanied the increase in ACTH when 100 micrograms CRF-41 was given to 6 normal male subjects. Chromatography of the basal and peak 15-min values showed that there was an equimolar increase in beta-LPH and beta-endorphin, to cause parallel release of ACTH, beta-endorphin and beta-LPH from the pro-opiocortin precursor.
Synthesis and characterization of crystalline tin oxide nanoparticles (2002)

Monodisperse non-aggregated spheroidal nanoparticles of SnO2 cassiterite are prepared through hydrolysis of tin isopropoxide in the presence of acetylacetone and p-toluenesulfonic acid, followed by ageing at 60 °C. The obtained sols remain stable for several months at 4 °C. The nanoparticles have been characterized in the solid state (xerosol) by powder X-ray diffraction, TEM, FTIR, TGA-DTA, and 119Sn MAS and 13C CP-MAS NMR. The mean size of the cassiterite oxide core is about 1–2 nm. These particles do not aggregate in suspension because their surfaces are protected by an hybrid organic–inorganic layer containing acetylacetonate ligands, acetylacetone, p-toluenesulfonates and water.
Fabrication of a Multilayer Implantable Cortical Microelectrode Probe to Improve Recording Potential (2021)

Intracortical neural probes are a key enabling technology for acquiring high fidelity neural signals within the cortex. They are viewed as a crucial component of brain-computer interfaces (BCIs) in order to record electrical activities from neurons within the brain. Smaller, more flexible, polymer-based probes have been investigated for their potential to limit the acute and chronic neural tissue response. Conventional methods of patterning electrodes and connecting traces on a single supporting layer can limit the number of recording sites which can be defined, particularly when designing narrower probes. We present a novel strategy of increasing the number of recording sites without proportionally increasing the size of the probe by using a multilayer fabrication process to vertically layer recording traces on multiple Parylene support layers, allowing more recording traces to be defined on a smaller probe width. Using this approach, we are able to define 16 electrodes on 4 supporting layers (4 electrodes per layer), each with a 30 <i>μ</i>m diameter recording window and 5 <i>μ</i>m wide connecting trace defined by conventional LWUV lithography, on an 80 <i>μ</i>m wide by 9 <i>μ</i>m thick microprobe. Prior to <i>in vitro</i> and <i>in vivo</i> validation, the multilayer probes are electrically characterized via impedance spectroscopy and evaluating crosstalk between adjacent layers. Demonstration of acute <i>in vitro</i> recordings in a cerebral organoid model and <i>in vivo</i> recordings in a murine model indicate the probe's capability for single unit recordings. This work demonstrates the ability to fabricate smaller, more compliant neural probes without sacrificing electrode density.
Resolving orientation-specific diffusion-relaxation features via Monte-Carlo density-peak clustering in heterogeneous brain tissue (2020)

Characterizing the properties and orientations of sub-voxel fiber populations, although essential to study white-matter architecture, microstructure and connectivity, remains one of the main challenges faced by the MRI microstructure community. While some progress has been made in overcoming this challenge using models, signal representations and tractography algorithms, these approaches are ultimately limited by their key assumptions or by the lack of specificity of the diffusion signal alone. In order to alleviate these limitations, we combine diffusion-relaxation MR acquisitions incorporating tensor-valued diffusion encoding, Monte-Carlo signal inversions that extract non-parametric intra-voxel distributions of diffusion tensors and relaxation rates, and density-based clustering techniques. This new approach, called "Monte-Carlo density-peak clustering" (MC-DPC), first delineates clusters in the diffusion-orientation subspace of the fiber-like diffusion-relaxation components output by Monte-Carlo signal inversions and then draws from the statistical aspect of these inversion algorithms to compute the median and interquartile range of orientation-resolved means of diffusivities and relaxation rates. Evaluating MC-DPC on tensor-valued diffusion-encoded and T2-weighted correlated datasets in silico and in vivo, we demonstrate its ability to simultaneously capture sub-voxel fiber orientations and cones of uncertainty, and measure fiber-specific diffusion-relaxation properties that are consistent with the known anatomy and existing literature. Straightforwardly translatable to other diffusion-relaxation correlation experiments probing $T_1$ and $T_2^*$, MC-DPC shows potential in tracking bundle-specific patient-control group differences and longitudinal microstructural changes, enabling new tools for microstructure-informed tractography, and mapping tract-specific myelination states.
ESR Properties of Irradiated (TMTSF)2.ClO4 (1985)

Abstract We present the first ESR investigation of the irradiated (TMTSF)2ClO4. Irradiations induce disorder on the conducting chains that suppresses both SC and SDW phases. Above a defect concentration of 0.2 % of spins/mole of TMTSF, (TMTSF)2 ClO4 presents the universal behavior of the strong irradiated ID organic conductors.
Application of H.264 for DoD sensor systems (2003)

The Department of Defense (DoD) Motion Imagery Standards Board (MISB) has adopted ITU-T Rec. H.264 (Baseline, Main, and Extended Profiles) to be the standard for applications constrained by low bandwidth channels (typically less than 1 Mb/s that may not be adequately supported by MPEG-2). H.264 will be carried over the MPEG-2 transport streams using ISO/IEC 13818-1:2000/FPDAM 3: "Information technology --Generic coding of moving pictures and associated audio: Systems, AMENDMENT 3: Transport of ISO/IEC 14496 part 10 [ITU-T H.264] video data over ISO/IEC 13818-1" (DRAFT). This is a part of a new principal called "Xon2" to support the "seamless" rollout of advanced video compression technologies without disrupting current and future operations and systems. "X" defines existing or future video compression technologies and "on2" refers to the use of MPEG-2 transport streams and files. The MISB predecessor VWG standardized on MPEG-2 (H.262) in 1996. "2on2" payloads have been successfully deployed using standards compliant MPEG-2 compressed video elementary streams, audio elementary streams, and SMPTE standard 336M KLV encoded metadata as MPEG-2 private data streams in support of unmanned aerial vehicle (UAV) operations. Building on this baseline "2on2" capability, "Xon2" will provide a migration path to inject improved compressions technologies, which will yield improved image quality and/or reduced bandwidths. NIMA’s Persistent Surveillance Office anticipates accelerating fielding of "264on2" using advanced video compression standard H.264 as described in this paper.
The complete genome sequence of the nitrile biocatalyst Rhodococcus rhodochrous ATCC BAA-870 (2020)

The sequence and comprehensive description of the R. rhodochrous ATCC BAA-870 genome will facilitate the additional exploitation of rhodococci for biotechnological applications, as well as enable further characterisation of this model organism. The genome encodes a wide range of enzymes, many with unknown substrate specificities supporting potential applications in biotechnology, including nitrilases, nitrile hydratase, monooxygenases, cytochrome P450s, reductases, proteases, lipases, and transaminases.
Effect of Intermediate Layer on Residual Stress Occurred in Hydroxyapatite Coating Implant. (1999)

Hydroxyapatite (HAp) is one of the most effective biomaterials used in an artificial bone and a dental designed implant. Since its mechanical reliability and workability are much lower than those of metal, it is often used as a coating material. However, cracking and delamination at the coating interface are induced by the residual stress which occurs in the coating process. In our previous report, the steep stress gradient in the coating layer and the increase in tensile residual stress on the surface of the substrate were obtained using the polychromatic X-ray diffraction. Therefore, an additional intermediate layer between the coating and the substrate material may decrease the residual stress in the coating layer. In this work, we describe the method to measure nondestructively three dimensional residual stress generated in the coating implant with the intermediate layer, using the polychromatic X-ray diffraction. As a result, the compressive residual stress in the coating layer of the hydroxyapatite coating titanium implant with the titania intermediate layer, made by atmospheric plasma-spray processing, was smaller than that of the implant coated only with hydroxyapatite.
Neutralizing Activity of BNT162b2-Elicited Serum (2021)

Variant SARS-CoV-2 and BNT162b2 Vaccine How well do serum samples obtained from persons injected with the BNT162b2 vaccine neutralize the P.1, B.1.1.7, and B.1.135 lineages of SARS-CoV-2, first ide...
PR-MCS: Perturbation Robust Metric for MultiLingual Image Captioning (2023)

Vulnerability to lexical perturbation is a critical weakness of automatic evaluation metrics for image captioning. This paper proposes Perturbation Robust Multi-Lingual CLIPScore(PR-MCS), which exhibits robustness to such perturbations, as a novel reference-free image captioning metric applicable to multiple languages. To achieve perturbation robustness, we fine-tune the text encoder of CLIP with our language-agnostic method to distinguish the perturbed text from the original text. To verify the robustness of PR-MCS, we introduce a new fine-grained evaluation dataset consisting of detailed captions, critical objects, and the relationships between the objects for 3, 000 images in five languages. In our experiments, PR-MCS significantly outperforms baseline metrics in capturing lexical noise of all various perturbation types in all five languages, proving that PR-MCS is highly robust to lexical perturbations.
Copper-Catalyzed C–N Coupling in the Synthesis of Integrase Inhibitors of Immunodeficiency Viruses (2013)

This contribution describes the total synthesis of a complex macrocyclic integrase inhibitor, a key enzyme involved in the infection process of various immunodeficiency viruses. The key transformation of the synthetic strategy was the selective C–N coupling of a sulfonamide to a heteroaryl bromide in the presence of potentially competing amide and carbamate functionalities. The transformation was accomplished with CuI catalysis using bypiridine as the ligand in the presence of base and enabled a convergent approach to the target molecule.
Low-Density Lipoprotein Oxidation and Its Prevention by Amidothionophosphate Antioxidants (1999)

Amidothionophosphates (AMTPs) are a novel group of antioxidants that are lacking in pro-oxidant activity. In this paper, we compare two different amidothionophosphates: 2-hydroxy-ethyl amido, diethyl thionophosphate (AMTP-B), which contains a single primary amido group, and N,N',N-tripropylamidothionophosphate (AMTP-3A), which contains three primary amido groups. The lipoprotein/medium partition coefficients of AMTP-3A and AMTP-B are 74 and 38, respectively. Both protected isolated human low density lipoprotein (LDL) against oxidative damage induced by copper sulfate. Oxidative damage to polyunsaturated acyl chains was determined by gas chromatography (GC), and oxidation kinetics were monitored by following the accumulation of conjugated dienes spectrophotometrically at 234 nm. The AMTP antioxidants significantly protected the LDL against Cu2+-induced oxidation. However, if the LDLs were already partially oxidized, protection against oxidation by the AMTPs was reduced. AMTP-3A was more effective in protecting LDL than was AMTP-B. The difference in antioxidant activity was attributed to the 15-fold higher reactivity of AMTP-3A toward peroxides. Oxidizability of plasma lipoproteins from guinea pigs injected with AMTPs was strongly reduced.
Arginine Depletion Therapy with ADI-PEG20 Limits Tumor Growth in Argininosuccinate Synthase–Deficient Ovarian Cancer, Including Small-Cell Carcinoma of the Ovary, Hypercalcemic Type (2020)

Preclinical <i>in vitro</i> and <i>in vivo</i> studies identified ADI-PEG20 as a potential therapy for patients with rare ovarian cancers, including SCCOHT.
Large scale data analysis and modelling in online services and advertising (2008)

No abstract available.
Photocatalytic activity of nanoparticles: the development of the standardized measurement for physiological conditions (2022)

Recently a new International Standard for testing nanomaterial photocatalytic activity under physiological conditions was issued by Technical Committee 229 (Nanotechnologies) of the International Organization for Standardization (ISO 20814:2019 Nanotechnologies-Testing the photocatalytic activity of nanoparticles for NADH oxidation). The document offers a robust, high throughput photocatalytic assay using a bio-compatible indicator nicotinamide amide dinucleotide (NAD) and provides a screening tool to gauge nanomaterial potency for phototoxicity. This paper describes the measurement principles behind this assay, the scope of the standard and its validation through an interlaboratory comparison study using a traceable standard reference material (SRM 1898).
Comparison of nitroethane, 2-nitro-1-propanol, lauric acid, Lauricidin® and the Hawaiian marine algae,Chaetoceros,for potential broad-spectrum control of anaerobically grown lactic acid bacteria (2012)

The gastrointestinal tract of bovines often contains bacteria that contribute to disorders of the rumen, and may also contain foodborne or opportunistic human pathogens as well as bacteria capable of causing mastitis in cows. Thus there is a need to develop broad-spectrum therapies that are effective while not leading to unacceptably long antibiotic withdrawal times. The effects of the CH(4)-inhibitors nitroethane (2 mg/mL), 2-nitro-1-propanol (2 mg/mL), lauric acid (5 mg/mL), the commercial product Lauricidin® (5 mg/mL), and a finely ground product of the Hawaiian marine algae, Chaetoceros (10 mg/mL), were compared in pure cultures of Streptococcus agalactia, Enterococcus faecium, Streptococcus bovis, and in a mixed lactic acid rumen bacterial culture. Lauricidin® and lauric acid exhibited the most bactericidal acidity against all bacteria. These results suggest potential animal health benefits from supplementing cattle diets with lauric acid or Lauricidin® to improve the health of the rumen and help prevent shedding of human pathogens.
Detection and strain typing of Brachyspira hyodysenteriae to support swine dysentery eradication and control. (2008)

This project ran from April 2006 until June 2008. It aimed to help reduce the cost of pig production by enhancing control of swine dysentery in key Australian herds. Control of this important disease would improve herd feed conversion, reduce mortalities, and improve pig welfare.
The dual role of the contact system in bacterial infectious disease (2007)

Hemostasis is a sensitive and tightly regulated process, involving the vascular endothelium and blood cells as well as factors of the coagulation and fibrinolytic cascades. Over the last four decades evidence has accumulated that during infection, inflammatory mediators from the microbe and/or host are capable to modulate the equilibrium between the procoagulant and anticoagulant status of the host. Dependent on the mode of activation, these changes can cause either local or systemic inflammatory reactions that may be beneficial or deleterious to the human host. The present review aims to present the state of the art with respect to the role of the contact system (also known as the intrinsic pathway of coagulation or the kallikrein/kinin system) in innate immunity and systemic inflammatory reactions.
Enhancement of T Due to Pressure Application in LaFeAsO1–xHx Studied by NMR (2015)

The prototypical iron-based high-Tc pnictide LaFeAsO1–xHx has superconducting double domes in the electronic phase diagram. Pressure application merges the double domes into a single dome, and the minimum Tc of 26K observed at x=0.2 goes up to 45K by applying a pressure of 3.0GPa. 75As nuclear magnetic resonance was performed at 3.0GPa to investigate the high-Tc mechanism. The relaxation rate divided by temperature, 1/T1T exhibits a plateau just above Tc and the value is enhanced by applying pressure. The plateau indicates that 1/T1 can be described by the Korringa relation, which suggests that a key factor to raise Tc is the density of states. So far as our results are concerned, spin fluctuations are not essential to achieve high Tc over 45K.
Implementation of a parallel-search trie-based scheme for fast IP lookup (2007)

The Internet Protocol (IP) address lookup is required to be resolved fast to keep up with data rate increases. To cope with the increasing number of entries, solutions for IP lookup based on random access memory (RAM), which store prefixes in a trie-based structure, are of interest. In this paper, we propose a flexible and fast trie-based IPlookup algorithm where parallel searching is performed. This algorithm performs lookup in a maximum of two memory-access times while using a feasible amount of memory.
Eight-Year Natural Course of a Femoral Neck Deformity Secondary to an Osteoid Osteoma Discovered at Fourteen Months of Age (2013)

Simon, A.L. MD; Ilharreborde, B. MD, PhD; Litzelmann, E. MD; Mazda, K. MD; Penneçot, G.F. MD Author Information
Low loss Type II regenerative Bragg gratings made with ultrafast radiation (2016)

A novel type of fiber Bragg grating is produced by annealing a type I-like grating that is written with multiple infrared femtosecond laser pulses through a phase mask under conditions that are typically used to fabricate thermally stable type II gratings. This new grating is created through a process similar to a regenerative one and displays low loss and high resilience in a 1000 °C ambient environment. Such gratings are ideally suited for quasi-distributed sensing at high temperatures.
Analysis 0f 293 cases after percutaneous ballon mitral valvuloplasty (2007)

Objective:To observe the short-term results and appropriateness of the use of percutaneous ballon mitral valvuloplasty(PBMV) on the patients with rheumatic mitral stenosis.Methods:293 patients with rheumatic mitral stenosis underwent percutaneous ballon mitral valvuloplasty(PBMV) with the Inoue balloon catheter.MVA,MPG,PAP,LAP,LAD,CO,the cardiac function(NYHA) and value noice variables were assessed before and after PBMV.Results:The mitral valave areas after PBMV is significantly larger than before PBMV.Blood dynamic factors and cardiac function after PBMV improved significantly than before PBMV(P0.1).Conclusion:PBMV is a safe and appropriate therapy with good short-term results for selected patients with mitral stenosis.
Robustness analysis of active damping methods for an inverter connected to the grid with an LCL-filter (2011)

Grid-connected converters usually employ an LCL-filter to reduce PWM harmonics. To avoid the well-known stability problems it is requested to use either passive or active damping methods. Active damping methods avoid losses and preserve the filter effectiveness but they are more sensitive to parameters variation. In this paper the robustness of active damping methods is investigated considering those using only the same state variable (grid-side or converter-side current) normally used for current control (filter-based) or those methods using more state-variables (multiloop). Simulation and experimental results validate the analysis.
Origins of thermal boundary conductance of interfaces involving organic semiconductors (2012)

We measure the room temperature thermal conductance of interfaces between an archetypal organic semiconductor copper phthalocyanine (CuPc) and several metals (aluminum, gold, magnesium, and silver) using the 3−ω method. The measured thermal boundary conductance (TBC) scales with bonding strength at the CuPc-metal interface, a correlation that is supported by molecular dynamics (MD) simulation, allowing the extrapolation of the effective interface Young's modulus. The trend in modeled interface modulus is in agreement with that deduced from adhesion tests, e.g., approximately 2 GPa for CuPc-gold and CuPc-silver interfaces, comparable to the van der Waals interaction strength of the materials. Using MD simulations in which the effects on thermal transport can be studied as a function of interfacial bond strength only, we isolate the relative contribution of acoustic mismatch and interface bond strength to TBC. Furthermore, measurements and modeling of organic/organic (e.g., CuPc/C60) interfaces reveal that the TBC of this system is not as sensitive to bonding strength as the CuPc/metal system, due to a larger overlap in the phonon density of states in the low frequency regime, despite the weak bonding between organic layers.