gebhart/patrepeval huggingface dataset:
Decentralized UAV Tracking with Networked Radar Systems (2021)

View Video Presentation: https://doi.org/10.2514/6.2021-1160.vid As traffic from unmanned aircraft increases, so does the need for infrastructure capable of detecting and tracking them. Research investigating both decentralized tracking algorithms and software architectures is critical to mitigate the struggles of centralized systems to collect, process, and disperse information in a timely manner. In this paper, we demonstrate a simulated air traffic system that tracks targets across a large geographical area using a decentralized radar network.
All-fiber ellipsometry (1984)

An all-fiber ellipsometer is constructed which uses a polarization-maintaining single-mode fiber as the polarization modulator. It is demonstrated that the all-fiber ellipsometer can be used to determine the optical constants of materials and as a surface state sensor.
Die Chemie und der Wurm: Caenorhabditis elegans als Plattform für das Zusammenführen von chemischer und biologischer Forschung (2011)

Abstract Dieser Aufsatz diskutiert die Nützlichkeit des Wurms Caenorhabditis elegans als Modellorganismus für Chemiker, die an der Untersuchung lebender Systeme interessiert sind. C. elegans, ein 1 mm langer Rundwurm, ist ein beliebter Modellorganismus in nahezu allen Gebieten der modernen Biologie. Der Wurm hat zahlreiche Eigenschaften, die ihn für die Biologie attraktiv machen: Er ist klein (&lt;1000 Zellen), transparent und genetisch leicht zu manipulieren. Trotz seiner Schlichtheit weist der Wurm komplexe Phänotypen auf, die mit seiner Mehrzelligkeit zusammenhängen: Er hat differenzierte Zelltypen und Organe, er altert und hat eine wohldefinierte Lebenserwartung, er kann lernen und besitzt ein Erinnerungsvermögen. Der Aufsatz will verdeutlichen, dass diese Mischung aus Einfachheit und Komplexität den Wurm zu einem besonders nützlichen Werkzeug macht, um die Beziehungen zwischen Phänomenen auf molekularer Ebene und der Ebene des Gesamtorganismus zu erforschen (Altern, Verhalten, Kognition, Anfälligkeit für Krankheiten). Es werden vornehmlich solche Forschungsarbeiten vorgestellt, die chemisch relevant sind. Außerdem werden Instrumente und Arbeitstechniken – biologischer, chemischer und physikalischer Natur – vorgestellt, die uns zur Erforschung des Wurms zur Verfügung stehen.
Mechanism of suppression of sustained neuronal spiking under high-frequency stimulation (2013)

Using Hodgkin-Huxley and isolated subthalamic nucleus (STN) model neurons as examples, we show that electrical high-frequency stimulation (HFS) suppresses sustained neuronal spiking. The mechanism of suppression is explained on the basis of averaged equations derived from the original neuron equations in the limit of high frequencies. We show that for frequencies considerably greater than the reciprocal of the neuron's characteristic time scale, the result of action of HFS is defined by the ratio between the amplitude and the frequency of the stimulating signal. The effect of suppression emerges due to a stabilization of the neuron's resting state or due to a stabilization of a low-amplitude subthreshold oscillation of its membrane potential. Intriguingly, although we neglect synaptic dynamics, neural circuity as well as contribution of glial cells, the results obtained with the isolated high-frequency stimulated STN model neuron resemble the clinically observed relations between stimulation amplitude and stimulation frequency required to suppress Parkinsonian tremor.
Reactivity of Rheumatic Fever and Scarlet Fever Patients' Sera with Group A Streptococcal M Protein, Cardiac Myosin, and Cardiac Tropomyosin: a Retrospective Study (2000)

Archived sera (collected in 1946) from acute rheumatic fever (ARF) and untreated scarlet fever and/or pharyngitis patients were reacted with streptococcal M protein, cardiac myosin, and cardiac tropomyosin. Except for very low levels to tropomyosin, antibodies to other antigens were not elevated in the sera of ARF patients relative to those of non-ARF patients, even though there was roughly equivalent exposure to group A streptococci. This suggests that antibodies to these molecules may not play a central role in the induction of ARF.
Improvement in IGZO-based thin film transistor performance using a dual-channel structure and electron-beam-irradiation (2018)

Abstract We investigated the effects of electron-beam-irradiation (EBI) on amorphous indium gallium zinc oxide (IGZO) films deposited by RF magnetron sputtering. The device performance of thin film transistors (TFTs) fabricated from these films was also evaluated. We conducted transmission electron microscopy and x-ray photoelectron spectroscopy to analyze the microstructure and chemical state of the synthesized IGZO. The EBI-treated IGZO TFTs achieved higher carrier mobility and on/off ratio than conventionally annealed IGZO TFTs. In addition, we found that a dual-channel structure shows electrical characteristics superior to those of a single-channel structure, with a carrier mobility of 18.1 cm 2 /V · s.
Randomized Phase II Trial of Carboplatin-Paclitaxel Versus Carboplatin-Paclitaxel-Trastuzumab in Uterine Serous Carcinomas That Overexpress Human Epidermal Growth Factor Receptor 2/neu (2018)

Purpose Uterine serous carcinoma is a rare, aggressive variant of endometrial cancer. Trastuzumab is a humanized monoclonal antibody that targets human epidermal growth factor receptor 2 (HER2)/neu, a receptor overexpressed in 30% of uterine serous carcinoma. This multicenter, randomized phase II trial compared carboplatin-paclitaxel with and without trastuzumab in patients with advanced or recurrent uterine serous carcinoma who overexpress HER2/neu. Methods Eligible patients had primary stage III or IV or recurrent HER2/neu-positive disease. Participants were randomly assigned to receive carboplatin-paclitaxel (control arm) for six cycles with or without intravenous trastuzumab (experimental arm) until progression or unacceptable toxicity. The primary end point was progression-free survival, which was assessed for differences between treatment arms via one-sided log-rank tests. Results From August 2011 to March 2017, 61 patients were randomly assigned. Forty progression-free survival-related events occurred among 58 evaluable participants. Among all patients, median progression-free survival was 8.0 months (control) versus 12.6 months (experimental; P = .005; hazard ratio [HR], 0.44; 90% CI, 0.26 to 0.76). Similarly, median progression-free survival was 9.3 (control) versus 17.9 (experimental) months among 41 patients with stage III or IV disease undergoing primary treatment ( P = .013; HR, 0.40; 90% CI, 0.20 to 0.80) and 6.0 (control) versus 9.2 months (experimental), respectively, among 17 patients with recurrent disease ( P = .003; HR, 0.14; 90% CI, 0.04 to 0.53). Toxicity was not different between treatment arms, and no unexpected safety signals emerged. Conclusion Addition of trastuzumab to carboplatin-paclitaxel was well tolerated and increased progression-free survival. These encouraging results deserve further investigation to determine their impact on overall survival in patients with advanced or recurrent uterine serous carcinoma who overexpress HER2/neu.
Molecular breeding of forage crops : proceedings of the 2nd Inernational Symposium, Molecular Breeding of Forage Crops, Lorne and Hamilton, Victoria, Australia, November 19-24, 2000 (2001)

Preface. 1. Breeding Forage Plants in the Genome Era G. Spangenberg, et al. 2. Breeding Methods for Forage and Amenity Grasses M.O. Humphreys. 3. Integrating Molecular Techniques to Maximise the Genetic Potential of Forage Legumes D.R. Woodfield, E.C. Brummer. 4. Modelling Plant Breeding Programs: Applications to Forage Crops M. Cooper, et al. 5. Bioinformatics Tools for Genome Projects T. Littlejohn. 6. Development and Implementation of Molecular Markers for Forage Crop Improvement J.W. Forster, et al. 7. Application of Molecular Markers to Genetic Diversity and Identity in Forage Crops R.E. Barker, S.E. Warnke. 8. Genetic Characterization of Heterogeneous Plant Populations in Forage, Turf and Native Grasses D.R. Huff. 9. Development of Molecular Markers for the Analysis of Apomixis H. Nakagawa, M. Ebina. 10. Molecular Breeding for Herbage Quality in Forage Crops M.D. Casler, H.F. Kaeppler. 11. Genetic Manipulation of Condensed Tannin Synthesis in Forage Crops M.Y. Gruber, et al. 12. Molecular Markers for Improving Nutritional Quality of Crop Residues for Ruminants C.T. Hash, et al. 13. Molecular Breeding of Forage Legumes for Virus Resistance R. Kalla, et al. 14. Trangenic Pest and Disease Resistant White Clover Plants C.R. Voisey, et al. 15. Molecular Breeding for Tolerance to Abiotic/Edaphic Stresses in Forage and Turfgrass R.R. Duncan, R.N. Carrow. 16. Molecular Interactions Between Lolium Grasses and Their Fungal Symbionts D.B. Scott. 17. AnIntegrated Functional Genomics and Genetics Approach for the Plant's Function in Symbiotic Nodulation P.M. Gresshoff, et al. 18. The Production of Value-Added Proteins in Transgenic Alfalfa S. Austin-Phillips, T. Ziegelhoffer. 19. Progress and Challenges: Forage Breeding in Temperate Australia K.F.M. Reed, et al. 20. Biosafety Risk Assessment and the Regulatory Framework for the Release of Transgenic Plants N.F. Millis. 21. The Future of Molecular Breeding of Forage Crops M.D. Hayward.
Tunable single-mode Fabry-Perot laser diode using a built-in external cavity and its modulation characteristics (2006)

A tunable single-mode laser is obtained by using a weakly coupled cavity structure involved in a coaxially packaged Fabry-Perot laser diode. The cleaved end facet of the coupling fiber becomes an optical reflector and forms an external cavity with a laser facet. The single-mode oscillation condition is controlled and stabilized by tuning the operating temperature. The tuning range is about 10 nm with the side-mode suppression ratio of more than 27 dB when the temperature changes from 11.5 degrees C to 25 degrees C. Direct modulation characteristics were investigated, and our results show that a shorter external cavity can bear deeper modulation depth.
An Inductance-Based Sensing System for Bellows-Driven Continuum Joints in Soft Robots (2017)

In this work we present a novel, inductance-based system to measure and control the motion of bellows-driven continuum joints in soft robots. The sensing system relies on coils of wire wrapped around the minor diameters of each bellows on the joint. As the bellows extend, these coils of wire become more distant, decreasing their mutual inductance. Measuring this change in mutual inductance allows us to measure the motion of the joint. By dividing the sensing of the joint into two sections and measuring the motion of each section independently, we are able to measure the overall deformation of the joint with a piecewise constant-curvature approximation. This technique allows us to measure lateral displacements that would be otherwise unobservable. When measuring bending, the inductance sensors measured the joint orientation with an RMS error of 1.1 . The inductance sensors were also successfully used as feedback to control the orientation of the joint. The sensors proposed and tested in this work provided accurate motion feedback that would be difficult to achieve robustly with other sensors. This sensing system enables the creation of robust, self-sensing, and soft robots based on bellows-driven continuum joints.
P-Derived Organic Cations as Structure-Directing Agents:  Synthesis of a High-Silica Zeolite (ITQ-27) with a Two-Dimensional 12-Ring Channel System (2006)

Recently, efforts have been made to synthesize large-pore, multidimensional zeolite frameworks as a basis for new catalysts to improve various hydrocarbon conversions. A new aluminosilicate zeolite, ITQ-27, has been prepared using the phosphorus-containing structure-directing agent, dimethyldiphenylphosphonium. Its crystal structure was determined in its calcined form by direct methods (FOCUS) on synchrotron powder diffraction data (lambda = 0.8702 A) after the unit cell and space group were determined from tilt electron diffraction experiments on individual microcrystals. The material crystallizes in space group Fmmm, where a = 27.7508(5) A, b = 25.2969(7) A, and c = 13.7923(4) A. The final model, refined by Rietveld methods, comprises seven unique T-sites forming a framework with straight 12-MR channels that are connected by 14-MR openings between them. (Corresponding 12-ring pore dimension is 6.94 A x 6.20 A.) Since access from one 14-MR opening to the next is through the 12-MR channel, the structure is best described as a two-dimensional, 12-MR framework.
Methylation of death-associated protein kinase is associated with cetuximab and erlotinib resistance (2012)

Anti-EGFR therapy is among the most promising molecular targeted therapies against cancer developed in the past decade. However, drug resistance eventually arises in most, if not all, treated patients. Emerging evidence has linked epigenetic changes, such as DNA methylation at CpG islands, to the development of resistance to multiple anticancer drugs. In addition, genes that are differentially methylated have increasingly been appreciated as a source of clinically relevant biomarker candidates. To identify genes that are specifically methylated during the evolution of resistance to anti-EGFR therapeutic agents, we performed a methylation-specific array containing a panel of 56 genes that are commonly known to be regulated through promoter methylation in two parental non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) cell lines and their resistant derivatives to either erlotinib or cetuximab. We found that death-associated protein kinase (DAPK) was hypermethylated in drug-resistant derivatives generated from both parental cell lines. Restoration of DAPK into the resistant NSCLC cells by stable transfection re-sensitized the cells to both erlotinib and cetuximab. Conversely, siRNA-mediated knockdown of DAPK induced resistance in the parental sensitive cells. These results demonstrate that DAPK plays important roles in both cetuximab and erlotinib resistance, and that gene silencing through promoter methylation is one of the key mechanisms of developed resistance to anti-EGFR therapeutic agents. In conclusion, DAPK could be a novel target to overcome resistance to anti-EGFR agents to improve the therapeutic benefit, and further evaluation of DAPK methylation as a potential biomarker of drug response is needed.
High-sensitivity HTS receiver module with hermetic thermal insulation waveguides (2013)

We have proposed a high-sensitivity high-Tc superconducting (HTS) receiver module with hermetic thermal insulation waveguides. The hermetic thermal insulation waveguide consists of two silver-plated aluminum oxide waveguides and copper wall. The waveguide with a gap between the aluminum oxide waveguides realizes thermal insulation between room temperature and low temperature. And the hermetic waveguide is connected to a vacuum flange to seal the vacuum chamber. This waveguide operates in the 3 GHz band and the dimension of this wavegide is 6.9 × 26.1 mm, one-third of the size of a conventional hollow metallic waveguide. The waveguide realizes an insertion loss of 0.4 dB and thermal conductivity 1/10 that of 2.2φ semi-rigid coaxial copper cable. The HTS receiver module is composed of the developed waveguides, an HTS filter, a cryogenic low-noise amplifier (LNA), and a limiter. The HTS receiver module realized low thermal noise of 60 K.
In vitro testing the potential of a novel chimeric IgG variant for inhibiting collagen fibrils formation in recurrent hereditary gingival fibromatosis: chimeric antibody in a gingival model. (2014)

Gingival fibromatosis is a progressive enlargement of the gingiva. It may hinder oral cavity hygiene and result in underlying bone loss. The long-term benefits of surgery cannot be predicted. On the other hand, alternative, efficient and non-invasive methods are not available at present. The aim of this study was to test the inhibitory effects of a chimeric IgG variant on collagen fibril formation in the cell culture of gingival fibroblasts taken from a patient with hereditary gingival fibromatosis with a high propensity for recurrence. Gingival biopsies were collected from the mandibular gingiva and used for histological evaluation as well as to establish a fibroblast culture. A histological evaluation was made in haematoxylin-eosin and Heidenhain's trichrome stained tissue sections. The inhibitory effect of a chimeric antibody on collagen fibril formation was determined in fibroblast cultures by using a collagen-specific Western blot and immunofluorescent staining. A histological evaluation revealed epithelial acanthosis with singular elongated rete pegs extending into the underlying connective tissue stroma that consisted of locally abundant, irregular collagen bundles. Based on observations with an in vitro model we conclude that a chimeric anti-collagen antibody efficiently inhibits collagen fibril accumulation in cell culture derived from diffuse, hereditary gingival fibromatosis that is characterized by a high propensity for recurrence (high proliferation index). Employing cell cultures from standardized group of patients with recurrent hereditary gingival fibromatosis as well as standarizing relevant 3D (tissue-like) models will be crucial for further tests of the antibody.
A Conserved DNA Damage Response Pathway Responsible for Coupling the Cell Division Cycle to the Circadian and Metabolic Cycles (2007)

The circadian clock drives endogenous oscillations of cellular and physiological processes with a periodicity of approximately 24 h. Progression of the cell division cycle (CDC) has been found to be coupled to the circadian clock, and it has been postulated that gating of the CDC by the circadian cycle may have evolved to protect DNA from the mutagenic effects of ultraviolet light. When grown under nutrient-limiting conditions in a chemostat, prototrophic strains of budding yeast, Saccharomyces cerevisiae, adopt a robust metabolic cycle of ultradian dimensions that temporally compartmentalizes essential cellular events. The CDC is gated by this yeast metabolic cycle (YMC), with DNA replication strictly segregated away from the oxidative phase when cells are actively respiring. Mutants impaired in such gating allow DNA replication to take place during the respiratory phase of the YMC and have been found to suffer significantly elevated rates of spontaneous mutation. Analogous to the circadian cycle, the YMC also employs the conserved DNA checkpoint kinase Rad53/Chk2 to facilitate coupling with the CDC. These studies highlight an evolutionarily conserved mechanism that seems to confine cell division to particular temporal windows to prevent DNA damage. We hypothesize that DNA damage itself might constitute a "zeitgeber", or time giver, for both the circadian cycle and the metabolic cycle. We discuss these findings in the context of a unifying theme underlying the circadian and metabolic cycles, and explore the relevance of cell cycle gating to human diseases including cancer.
Organisation d'une masse documentaire électronique présentée à des lecteurs potentiels (2004)

info:eu-repo/semantics/published
Electrically Tunable Chip-Scale Semiconductor Microdisk Phase Modulators (2006)

We have demonstrated a 12 micron radius InP optical microdisk resonator functioning as a phase modulator in an external Mach-Zehnder interferometer. The device’s small Vn characteristic make it attractive as a low power chip scale modulator.
Contemporary Mathematics: Algebra and Computer Science-volume 677 (2016)

Benjamin Fine is a contributing author, "On secret sharing protocols" with Chi Sing Chum, Anja IS Moldenhauer, Gerhard Rosenberger, and Xiaowen Zhang. Book description: This volume contains the proceedings of three special sessions: Algebra and Computer Science, held during the Joint AMS-EMS-SPM meeting in Porto, Portugal, June 10-13, 2015; Groups, Algorithms, and Cryptography, held during the Joint Mathematics Meeting in San Antonio, TX, January 10-13, 2015; and Applications of Algebra to Cryptography, held during the Joint AMS-Israel Mathematical Union meeting in Tel-Aviv, Israel, June 16-19, 2014. Papers contained in this volume address a wide range of topics, from theoretical aspects of algebra, namely group theory, universal algebra and related areas, to applications in several different areas of computer science. From the computational side, the book aims to reflect the rapidly emerging area of algorithmic problems in algebra, their computational complexity and applications, including information security, constraint satisfaction problems, and decision theory. The book gives special attention to recent advances in quantum computing that highlight the need for a variety of new intractability assumptions and have resulted in a new area called group-based cryptography.
SemanticPaint (2015)

We present a real-time, interactive system for the geometric reconstruction, object-class segmentation and learning of 3D scenes [Valentin et al. 2015]. Using our system, a user can walk into a room wearing a depth camera and a virtual reality headset, and both densely reconstruct the 3D scene [Newcombe et al. 2011; Nießner et al. 2013; Prisacariu et al. 2014]) and interactively segment the environment into object classes such as 'chair', 'floor' and 'table'. The user interacts physically with the real-world scene, touching objects and using voice commands to assign them appropriate labels. These user-generated labels are leveraged by an online random forest-based machine learning algorithm, which is used to predict labels for previously unseen parts of the scene. The predicted labels, together with those provided directly by the user, are incorporated into a dense 3D conditional random field model, over which we perform mean-field inference to filter out label inconsistencies. The entire pipeline runs in real time, and the user stays 'in the loop' throughout the process, receiving immediate feedback about the progress of the labelling and interacting with the scene as necessary to refine the predicted segmentation.
In MOF eingebettete Enzyme für die kontinuierliche Durchflusskatalyse in wässrigen und organischen Lösungsmitteln (2022)

Abstract Um das Potenzial von Enzymen in der zellfreien Biokatalyse voll auszuschöpfen, ist eine Stabilisierung der katalytisch aktiven Proteine und deren Integration in effiziente Reaktorsysteme erforderlich. Obwohl in den letzten Jahren erste Schritte zur Immobilisierung solcher Biomoleküle in metallorganischen Gerüsten (MOFs) unternommen wurden, waren diese Demonstrationen auf Batch‐Experimente und wässrige Bedingungen beschränkt. Hier demonstrieren wir ein kontinuierliches Enzymreaktorsystem auf MOF‐Basis mit hoher Produktivität und Stabilität, das auch für organische Lösungsmittel geeignet ist. Unter wässrigen Bedingungen wurde die Stabilität des Enzyms um das 30‐fache erhöht, und die Raum‐Zeit‐Ausbeute übertraf die mit anderen Enzym‐Immobilisierungsstrategien erzielten Werte um eine Größenordnung. Es ist herauszuheben, dass die hier gezeigte Infiltration der Proteine in das MOF keine zusätzliche Funktionalisierung erfordert, was eine zeit‐ und kosteneffiziente Herstellung der Biokatalysatoren mit markierungsfreien Enzymen ermöglicht.