gebhart/patrepeval huggingface dataset:
High Q film bulk acoustic resonator from 2.4 to 5.1 GHz (2004)

This paper describes a high Q, free-standing, narrow beam supported FBAR (film bulk acoustic-wave resonator) fabricated with silicon micromachining. The resonator is composed of Metal/ZnO/Metal/Si/sub x/N/sub y/ composite layers, which are suspended by narrow Si/sub x/N/sub y//Metal beams to minimize energy leakage to the substrate. The highest Q (quality) factors we have obtained with this new structure are 1,587 and 769 at 2.7 and 5.1 GHz, respectively. Moreover, for a monolithic integration of FBAR with an integrated circuit (IC), we have developed a simple, low cost, low temperature, fully IC-compatible post CMOS process that is based on XeF/sub 2/ dry-release with silicon as a sacrificial layer.
Esophageal overtubes provide no benefit to safety or technical success in upper gastrointestinal tract endoscopic suturing (2019)

<b>Background and study aim</b> The role of esophageal overtubes in upper gastrointestinal endoscopic suturing is unknown. This study aimed to determine whether overtube use was associated with technical success or adverse events. <b>Patients and methods</b> A retrospective review of consecutive patients who underwent endoscopic suturing for various indications was performed. <b>Results</b> A total of 719 patients underwent endoscopic suturing for various indications, including endoscopic bariatric procedures in 262, stent fixation in 258, defect closure in 190, and hemostasis in nine. An overtube was used in 186 procedures (25.9 %). Technical success was achieved in all cases. Minor mucosal trauma occurred in 15 cases (8.1 %) with use of an overtube, and none without an overtube ( <i>P</i> < 0.0001). No full-thickness esophageal perforation or hemorrhage related to overtube use or the suturing device occurred. <b>Conclusions</b> Endoscopic suturing can be performed safely for a variety of indications, including endoscopic bariatric procedures, defect repair, and stent fixation without an esophageal overtube. Minor esophageal mucosal trauma and equipment cost are increased when an overtube is used.
On in-network computation via wireless multiple-access channels with applications (2012)

Wireless sensor networks have increasingly been gaining importance because of their applications in many domains, including remote sensing, traffic management, disaster alarm, and anomaly detection. In many of these applications, sensor nodes cooperate in obtaining an estimate of a control or environmental parameter to achieve capabilities that cannot be achieved by letting the nodes work individually. Cooperation may take on many forms, but it usually involves the computation of weighted averages, maximum values, or polynomial functions of sensor readings. As the readings are available at spatially distributed nodes, wireless communication resources have to be used as efficiently as possible in the computation of the underlying functions. In this paper, we present novel techniques that exploit recent ideas on analog computation coding over wireless channels and show how the proposed techniques can be applied in real-world estimation problems.
Energy-efficient Blood Pressure Monitoring based on Single-site Photoplethysmogram on Wearable Devices (2021)

The paper proposes accurate Blood Pressure Monitoring (BPM) based on a single-site Photoplethysmographic (PPG) sensor and provides an energy-efficient solution on edge cuffless wearable devices. Continuous PPG signal preprocessed and used as input of the Artificial Neural Network (ANN), and outputs systolic BP (SBP), diastolic BP (DBP), and mean arterial BP (MAP) values for each heartbeat. The improvement of the BPM accuracy is obtained by removing outliers in the preprocessing step and the whole-based inputs compared to parameter-based inputs extracted from the PPG signal. Performance obtained is $3.42 \pm 5.42$ mmHg (MAE $\pm$ RMSD) for SBP, $1.92 \pm 3.29$ mmHg for DBP, and $2.21 \pm 3.50$ mmHg for MAP which is competitive compared to other studies. This is the first BPM solution with edge computing artificial intelligence as we have learned so far. Evaluation experiments on real hardware show that the solution takes 42.2 ms, 18.2 KB RAM, and 2.1 mJ average energy per reading.
The role of fibrinogen and fibrinogen concentrate in cardiac surgery: an international consensus statement from the Haemostasis and Transfusion Scientific Subcommittee of the European Association of Cardiothoracic Anaesthesiology (2019)

To date, data regarding the efficacy and safety of administering fibrinogen concentrate in cardiac surgery are limited. Studies are limited by their low sample size and large heterogeneity with regard to the patient population, by the timing of fibrinogen concentrate administration, and by the definition of transfusion trigger and target levels. Assessment of fibrinogen activity using viscoelastic point-of-care testing shortly before or after weaning from cardiopulmonary bypass in patients and procedures with a high risk of bleeding appears to be a rational strategy. In contrast, the use of Clauss fibrinogen test for determination of plasma fibrinogen level can no longer be recommended without restrictions due to its long turnaround time, high inter-assay variability and interference with high heparin levels and fibrin degradation products. Administration of fibrinogen concentrate for maintaining physiological fibrinogen activity in the case of microvascular post-cardiopulmonary bypass bleeding appears to be indicated. The available evidence does not suggest aiming for supranormal levels, however. Use of cryoprecipitate as an alternative to fibrinogen concentrate might be considered to increase plasma fibrinogen levels. Although conclusive evidence is lacking, fibrinogen concentrate does not seem to increase adverse outcomes (i.e., thromboembolic events). Large prospective multi-centre studies are needed to better define the optimal perioperative monitoring tool, transfusion trigger and target levels for fibrinogen replacement in cardiac surgery.
All‐Printed Ultrahigh‐Responsivity MoS2 Nanosheet Photodetectors Enabled by Megasonic Exfoliation (2022)

Printed 2D materials, derived from solution-processed inks, offer scalable and cost-effective routes to mechanically flexible optoelectronics. With micrometer-scale control and broad processing latitude, aerosol-jet printing (AJP) is of particular interest for all-printed circuits and systems. Here, AJP is utilized to achieve ultrahigh-responsivity photodetectors consisting of well-aligned, percolating networks of semiconducting MoS<sub>2</sub> nanosheets and graphene electrodes on flexible polyimide substrates. Ultrathin (≈1.2 nm thick) and high-aspect-ratio (≈1 μm lateral size) MoS<sub>2</sub> nanosheets are obtained by electrochemical intercalation followed by megasonic atomization during AJP, which not only aerosolizes the inks but also further exfoliates the nanosheets. The incorporation of the high-boiling-point solvent terpineol into the MoS<sub>2</sub> ink is critical for achieving a highly aligned and flat thin-film morphology following AJP as confirmed by grazing-incidence wide-angle X-ray scattering and atomic force microscopy. Following AJP, curing is achieved with photonic annealing, which yields quasi-ohmic contacts and photoactive channels with responsivities exceeding 10<sup>3</sup> A W<sup>-1</sup> that outperform previously reported all-printed visible-light photodetectors by over three orders of magnitude. Megasonic exfoliation coupled with properly designed AJP ink formulations enables the superlative optoelectronic properties of ultrathin MoS<sub>2</sub> nanosheets to be preserved and exploited for the scalable additive manufacturing of mechanically flexible optoelectronics.
DOI-PET image reconstruction with accurate system modeling that reduces redundancy of the imaging system (2003)

A high-performance positron emission tomography (PET) scanner, which measures depth-of-interaction (DOI) information, is under development at the National Institute of Radiological Sciences in Japan. Image reconstruction methods with accurate modeling of the system response functions have been successfully used to improve PET image quality. It is, however, difficult to apply these methods to the DOI-PET scanner because the dimension of DOI-PET data increases in proportion to the square of the number of DOI layers. In this paper, we propose a compressed imaging system model for DOI-PET image reconstruction, in order to reduce computational cost while keeping image quality. The basic idea of the proposed method is that the DOI-PET imaging system is highly redundant. First, DOI-PET data is transformed into compact data so that data bins with highly correlating sensitivity functions are combined. Then image reconstruction methods based on accurate system modeling, such as the maximum likelihood expectation maximization (ML-EM), are applied. The proposed method was applied to simulated data for the DOI-PET scanner operated in 2-D mode. Then the tradeoff between the background noise and the spatial resolution was investigated. Numerical simulation results show that the proposed method followed by ML-EM reduces computational cost effectively while keeping the advantages of the accurate system modeling and DOI information.
Fabrication of the TiC/6061 Aluminum Alloy Composite by the Combination Process of Combustion Reaction and Vortex Technique (2004)

Titanium carbide (TiC) reinforced 6061 aluminum alloy composites were fabricated by the combination process of combustion reaction and vortex technique. Titanium, carbon and 6061Al powders were blended and consolidated. When the consolidated powder blend was heated, combustion reaction occurred near the melting point of aluminum and, as a result, TiC particles were formed in 6061Al matrix (base composite). The in situ formed TiC particles were spherical shape with 2-5 μm in diameter. The combustion synthesized TiC/6061Al base composite was then added into molten 6061Al to control the volume fraction of TiC particle (5, 10 and 15 vol%TiC). Regardless of the volume fraction, TiC particles in the base composite were easily incorporated and dispersed uniformly in the 6061Al matrix within 300 seconds stirring. On the other hand, when the commercial TiC powders were directly added in molten 6061Al alloy, 1800 seconds or longer stirring time was necessary to achieve incorporation (more than 95%) and uniform dispersion of TiC. The mechanical properties of the composites fabricated using the base composite were roughly equal to those using commercial TiC powder.
Effects of Geometrical and Thermophysical Parameters on Heat Transfer Measurements in Small-Diameter Channels (2005)

An experimental investigation of the liquid flow friction factor and heat transfer coefficient in small diameter channels is presented. Rectangular and circular mini-channels with hydraulic diameters from 0.77 to 2.01 mm were used. Literature in the 1990s showed scattered experimental results and concluded that new physical phenomena in mini-channels could occur. However, the present experimental results show that three main causes can explain how different results were obtained in mini-channels compared to macro-tubes: uncertainties on the channel dimensions, inlet and outlet singular pressure losses, and longitudinal heat conduction. When these elements are taken into account, good agreement is found with standard correlations or theories.
Patient Perspective on Acute Intermittent Porphyria with Frequent Attacks: A Disease with Intermittent and Chronic Manifestations (2018)

In this study population of acute intermittent porphyria with frequent attacks, most patients had symptoms during and between attacks. In these patients, acute intermittent porphyria appears to have acute exacerbations as well as chronic day-to-day manifestations, and is not just intermittent as its name implies. As a result, patients reported limitations in their ability to function across multiple domains of their lives on a regular basis and not just during acute attacks.
Total synthesis of pseudomonic acid C: application of the alkoxyselenation reaction in organic synthesis (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTotal synthesis of pseudomonic acid C: application of the alkoxyselenation reaction in organic synthesisA. P. Kozikowski, R. J. Schmiesing, and K. L. SorgiCite this: J. Am. Chem. Soc. 1980, 102, 21, 6577–6580Publication Date (Print):October 8, 1980Publication History Published online1 May 2002Published inissue 8 October 1980https://pubs.acs.org/doi/10.1021/ja00541a044https://doi.org/10.1021/ja00541a044research-articleACS PublicationsRequest reuse permissionsArticle Views427Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Construction of a physical map of the chromosome of Shigella flexneri 2a and the direct assignment of nine virulence‐associated loci identified by Tn5 insertions (1991)

To establish the molecular basis of the chromosomal virulence genes of Shigella flexneri 2a (YSH6000), a Notl restriction map of the chromosome was constructed by exploiting Notl-linking clones, partial Notl digestion and DNA probes from various genes of Escherichia coli K-12. The map revealed at least three local differences in the placements of genes between YSH6000 and E. coli K-12. Using the additional Notl sites introduced by Tn5 insertion, nine virulence loci identified previously by random Tn5 insertions were physically mapped on the chromosome. To demonstrate the versatility of the Notl map in direct assignment of the virulence loci tagged by Tn5 to a known genetic region in E. coli K-12, the major class of avirulent mutants defective in the core structure of lipopolysaccharide (LPS) was examined for the sites of Tn5 insertions. The two Notl segments created by the Tn5 insertion in the Notl fragment were analysed by Southern blotting with two DNA probes for the 5' and 3' flanking regions of the rfa region, and shown to hybridize separately with each of them, confirming the sites of Tn5 in the rfa locus. This approach will facilitate direct comparison genetically mapped Tn5 insertion mutations of S. flexneri with genes physically determined in E. coli K-12.
Association between composite scores of domain-specific cognitive functions and regional patterns of atrophy and functional connectivity in the Alzheimer’s disease spectrum (2020)

Consistent associations between cognitive domain scores and both regional atrophy and network-specific functional connectivity (except for the visual network), support the utility of a multicentric and cognitive domain approach towards explicating the relationship between imaging markers and cognition in the AD-spectrum.
YdgG (TqsA) Controls Biofilm Formation inEscherichia coliK-12 through Autoinducer 2 Transport (2005)

YdgG is an uncharacterized protein that is induced in Escherichia coli biofilms. Here it is shown that deletion of ydgG decreased extracellular and increased intracellular concentrations of autoinducer 2 (AI-2); hence, YdgG enhances transport of AI-2. Consistent with this hypothesis, deletion of ydgG resulted in a 7,000-fold increase in biofilm thickness and 574-fold increase in biomass in flow cells. Also consistent with the hypothesis, deletion of ydgG increased cell motility by increasing transcription of flagellar genes (genes induced by AI-2). By expressing ydgG in trans, the wild-type phenotypes for extracellular AI-2 activity, motility, and biofilm formation were restored. YdgG is also predicted to be a membrane-spanning protein that is conserved in many bacteria, and it influences resistance to several antimicrobials, including crystal violet and streptomycin (this phenotype could also be complemented). Deletion of ydgG also caused 31% of the bacterial chromosome to be differentially expressed in biofilms, as expected, since AI-2 controls hundreds of genes. YdgG was found to negatively modulate expression of flagellum- and motility-related genes, as well as other known products essential for biofilm formation, including operons for type 1 fimbriae, autotransporter protein Ag43, curli production, colanic acid production, and production of polysaccharide adhesin. Eighty genes not previously related to biofilm formation were also identified, including those that encode transport proteins (yihN and yihP), polysialic acid production (gutM and gutQ), CP4-57 prophage functions (yfjR and alpA), methionine biosynthesis (metR), biotin and thiamine biosynthesis (bioF and thiDFH), anaerobic metabolism (focB, hyfACDR, ttdA, and fumB), and proteins with unknown function (ybfG, yceO, yjhQ, and yjbE); 10 of these genes were verified through mutation to decrease biofilm formation by 40% or more (yfjR, bioF, yccW, yjbE, yceO, ttdA, fumB, yjiP, gutQ, and yihR). Hence, it appears YdgG controls the transport of the quorum-sensing signal AI-2, and so we suggest the gene name tqsA.
STOMP: A Tool for Evaluation of Scheduling Policies in Heterogeneous Multi-Processors (2020)

The proliferation of heterogeneous chip multiprocessors in recent years has reached unprecedented levels. Traditional homogeneous platforms have shown fundamental limitations when it comes to enabling high-performance yet-ultra-low-power computing, in particular in application domains with real-time execution deadlines or criticality constraints. By combining the right set of general purpose cores and hardware accelerators together, along with proper chip interconnects and memory technology, heterogeneous chip multiprocessors have become an effective high-performance and low-power computing alternative. One of the challenges of heterogeneous architectures relates to efficient scheduling of application tasks (processes, threads) across the variety of options in the chip. As a result, it is key to provide tools to enable early-stage prototyping and evaluation of new scheduling policies for heterogeneous platforms. In this paper, we present STOMP (Scheduling Techniques Optimization in heterogeneous Multi-Processors), a simulator for fast implementation and evaluation of task scheduling policies in multi-core/multi-processor systems with a convenient interface for "plugging" in new scheduling policies in a simple manner. Thorough validation of STOMP exhibits small relative errors when compared against closed-formed equivalent models during steady-state analysis.
$1.62\mu \mathrm{m}$ Global Shutter Quantum Dot Image Sensor Optimized for Near and Shortwave Infrared (2021)

We have developed a <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$1.62\mu \mathrm{m}$</tex> pixel pitch global shutter sensor optimized for imaging in the near infrared (NIR) and shortwave infrared (SWIR) regions of the light spectrum. This breakthrough was made possible through the use of our colloidal Quantum Dot (QD) thin film technology, which we have named Quantum Film (QF). We have scaled up this new platform technology to our 300mm manufacturing toolset. The challenges associated with the introduction of solution-processed, colloidally grown lead sulfide (PbS) QDs in an industrial 300mm fab environment were successfully overcome. The QF photodiodes, leveraging either NIR or SWIR sensitive QDs, were optimized for high quantum efficiency (QE), low dark current and immunity to operating stress. Global shutter pixel arrays, with pixel pitch of <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$2.2\mu \mathrm{m}$</tex> and <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$1.62\mu \mathrm{m}$</tex> exhibit unprecedented QE of >50% and MTF @ Nyquist/2 of 0.75 and 0.6, respectively. The robustness of our 300mm Quantum Film technology was fully assessed and reliability in terms of meeting all required lifetime specifications for consumer electronics and other potential applications has been demonstrated.
Adaptive Driving Cycles of EVs for Reducing Energy Consumption (2021)

A driving cycle is a time series of a vehicle’s speed, reflecting its movement in real road conditions. In addition to certification and comparative research, driving cycles are used in the virtual design of drive systems and embedded control algorithms, traffic management and intelligent road transport (traffic engineering). This study aimed to develop an adaptive driving cycle for a known route to optimize the energy consumption of an electric vehicle and improve the driving range. A novel distance-based adaptive driving cycle method was developed. The proposed algorithm uses the segmentation and iterative synthesis procedures of Markov chains. Energy consumption during driving is monitored on an ongoing basis using Gaussian process regression, and speed and acceleration are corrected adaptively to maintain the planned energy consumption. This paper presents the results of studies of simulated driving cycles and the performance of the algorithm when applied to the real recorded driving cycles of an electric vehicle.
Renal Magnetic Resonance Appearance After Piezoelectric and Electrohydraulic Lithotripsy* (1990)

Morphologic changes of the kidney after extracorporeal shock wave lithotripsy (SWL) have been demonstrated by magnetic resonance imaging (MRI) to be present in as many as 85% of patients treated with first-generation electrohydraulic lithotripters. We compared the acute renal morphologic changes produced by a second-generation piezoelectric machine (Wolf Piezolith 2300) with those of an electrohydraulic lithotripter (Dornier HM3). All patients were studied with renal MRI scans 24 hours after lithotripsy and then serially with repeat MRI scans at 2 weeks and at 1 month if any changes were noted on the prior study. Only 1 of 20 (5 %) of patients treated on the Wolf Piezolith 2300 showed any changes by MRI, the change consisting of localized perinephric edema present on the scan at 24 hours that resolved spontaneously by 2 weeks. In contrast, 2 of 4 of the patients treated on a Dornier HM3 showed specific renal changes, including subcapsular fluid collections and loss of corticomedullary demarcation, and all 4 had acutely increased renal volume on the treated side. These findings suggest that piezoelectric lithotripsy may be less damaging acutely to the renal parenchyma and surrounding tissues than electrohydraulic machines.