gebhart/patrepeval huggingface dataset:
A sátira na poesia realista portuguesa (2021)

Com as Odes Modernas (1865; 2.ª ed., revista e aumentada, 1875), de Antero de Quental, e com a Visão dos Tempos(1864) e Tempestades Sonoras (1864), de Teófilo Braga, inaugura-se a chamada escola realista portuguesa; ou, dito de outra forma, o período do terceiro Romantismo (de tipo social, à Hugo e Michelet), cujo conceito de poesia continua o empreendimento da primeira geração romântica portuguesa: a atribuição à literatura de uma superior função ética, instrutiva e progressista, de um comprometimento social, ideológico, político e filosófico. Neste artigo, procuro mostrar de que modo a poesia satírica (ou com tonalidades satíricas) de alguns dos mais importantes poetas portugueses de meados do século xix persegue esse objetivo de moralização dos costumes. Abordo autores cuja obra, apesar de muito ou razoavelmente conhecida, tem sido pouco estudada no que tem a ver com a vertente satírica: Antero de Quental, Guilherme de Azevedo, Bulhão Pato e João de Deus.
Two-Dimensional Phosphopeptide Mapping (2009)

A major mechanism that cells use to regulate protein function is by phos-phorylation and/or dephosphorylation of serine, theonine and tyrosine residues. Phosphopeptide mapping of these phosphorylated residues allows investigation into the positive and negative regulatory roles these sites may play in vivo. In addition, phosphopeptide mapping can uncover the specific phosphorylated residue and hence, kinase recognition site, thus helping in the identification of the relevant kinase(s) and/or phosphatase(s). Two-Dimensional (2D) Phosphopeptide mapping can utilize in vivo and in vitro 32P labeled proteins (1–6). Briefly, 32P labeled proteins are purified by SDS-PAGE, transferred to a nitrocellulose filter and digested by proteases or chemicals. The phosphopeptides are then separated by electrophoresis on thin layer cellulose (TLC) plate in the first dimension followed by thin layer chomatography in an organic buffer in the sond dimension. The TLC plate is then exposed to autoradiographic (ARG) film or phosphor-imager screen and the position of the 32P containing peptides are thus identified. Specific phos-phopeptides can then be excised from the TLC plate and analyzed further by amino acid hydrolysis to identify the specific phosphorylated residue(s) and/or by manual amino-terminal sequencing to obtain the position of the phosphory-lated residue(s) relative to the protease cleavage site (3). In addition, mixing in vivo with in vitro 32P-labeled proteins can yield confirmation of the specific phosphorylated residue and the relevant kinase.
Mechanical Stress Impact of Assembly Processes onto a Stress-sensitive Testchip (2011)

A semiconductor die typically undergoes a variety of assembly processes, each of them influencing the mechanical stress environment of the chip. We report on a stress-sensitive testchip and its application to measure and characterize the respective stress distributions across the die. Particularly in the field of MEMS and sensor devices, even low stresses might deteriorate the electrical performance of a device significantly, while higher stress levels may even cause cracks and irreversible damage. This is why the present methodology has a high potential to develop into a useful tool in the field of sensor package development. After a brief introduction to the sensing principle, we investigate the stress distribution in various sample assemblies – all of them targeting pressure sensors. Typical low stress packages use silicone based soft elastic encapsulations. Changing to a harder material with a young’s modulus comparable to standard mold compounds, we demonstrate an increase of the average stress level by more than one order of magnitude.
Solid-Phase Synthesis of Imidazo[4,5-b]pyridin-2-ones and Related Urea Derivatives by Cyclative Cleavage of a Carbamate Linkage (2002)

A solid-phase synthesis of substituted cyclic urea derivatives as potential heterocyclic library scaffolds is described. 2-Amino-3-nitropyridine is attached to Wang resin via a carbamate linkage. Reduction of the nitro group was achieved with SnCl(2).2H(2)O. Reductive alkylation with a range of substituted benzaldehydes followed by cyclative cleavage afforded a small library of 3-substituted imidazo[4,5-b]pyridine-2-ones in 33-45% yield and 59-88% purity. Subsequently, this methodology was applied to the synthesis of 3-substituted imidazo[4,5-f]quinolin-2-ones.
Scanned Document Compression Using Block-Based Hybrid Video Codec (2013)

This paper proposes a hybrid pattern matching/transform-based compression method for scanned documents. The idea is to use regular video interframe prediction as a pattern matching algorithm that can be applied to document coding. We show that this interpretation may generate residual data that can be efficiently compressed by a transform-based encoder. The efficiency of this approach is demonstrated using H.264/advanced video coding (AVC) as a high-quality single and multipage document compressor. The proposed method, called advanced document coding (ADC), uses segments of the originally independent scanned pages of a document to create a video sequence, which is then encoded through regular H.264/AVC. The encoding performance is unrivaled. Results show that ADC outperforms AVC-I (H.264/AVC operating in pure intramode) and JPEG2000 by up to 2.7 and 6.2 dB, respectively. Superior subjective quality is also achieved.
A Yeast RNA-Binding Protein Shuttles between the Nucleus and the Cytoplasm (1994)

RNA-binding proteins have been suggested to move in association with RNA as it leaves the nucleus. The NPL3 gene of the yeast Saccharomyces cerevisiae encodes in nuclear protein with consensus RNA-binding motifs and similarity to heterogeneous nuclear ribonucleoproteins and members of the S/R protein family. We show that although Npl3 is located in the nucleus, it can shuttle between nuclei in yeast heterokaryons. In contrast, other nucleus-targeted proteins do not leave the nucleus under similar conditions. Mutants missing the RNA-binding motifs or the N terminus are still capable of shuttling in and out of the nucleus. Npl3 mutants missing the C terminus fail to localize to the nucleus. Overproduction of Npl3 in wild-type cells shows cell growth. This toxicity depends on the presence of series of unique repeats in the N terminus and localization to the nucleus. We suggest that the properties of Npl3 are consistent with it being involved in export of RNAs from the nucleus.
Using Resampling Techniques to Compute Confidence Intervals for the Harmonic Mean of Rate-Based Performance Metrics (2010)

Rate-based metrics such as floating point operations per second, instructions per cycle and so forth are commonly used to measure computer performance. In addition to the average or mean performance of the metric, indicating the precision of the mean using confidence intervals helps to make informed decisions and comparisons with the data. In this paper, we discuss the determination of confidence intervals for the harmonic mean of rate-based metrics using two statistical resampling techniques - Jackknife and Bootstrap. We show using Monte Carlo simulations that resampling indeed works as expected, and can be used for generating confidence intervals for harmonic mean.
Incremental polyphonic audio to score alignment using beat tracking for singer robots (2009)

We aim at developing a singer robot capable of listening to music with its own ¿ears¿ and interacting with a human's musical performance. Such a singer robot requires at least three functions: listening to the music, understanding what position in the music is being performed, and generating a singing voice. In this paper, we focus on the second function, that is, the capability to align an audio signal to its musical score represented symbolically. Issues underlying the score alignment problem are: (1) diversity in the sounds of various musical instruments, (2) difference between the audio signal and the musical score, (3) fluctuation in tempo of the musical performance. Our solutions to these issues are as follows: (1) the design of features based on a chroma vector in the 12-tone model and onset of the sound, (2) defining the rareness for each tone based on the idea that scarcely used tone is salient in the audio signal, and (3) the use of a switching Kalman filter for robust tempo estimation. The experimental result shows that our score alignment method improves the average of cumulative absolute errors in score alignment by 29% using 100 popular music tunes compared to the beat tracking without score alignment.
High-fidelity trapped-ion state detection with an integrated avalanche photodiode (2023)

Integrated technologies represent a key enabling capability for future compact and portable atomic physics systems, including optical clocks and other sensors. In this talk, I will discuss our recent demonstration of high-fidelity detection of the state of a trapped Sr+ ion with a single-photon avalanche detector (SPAD) integrated into a microfabricated surface-electrode trap. Using an adaptive technique, we achieve ion state detection in 450 us with 99.92(1)% average fidelity. I will also discuss ongoing efforts to combine integrated detectors with integrated photonics to enable ion traps that completely eliminate the need for free-space optics for light delivery and collection.
Supplementary Figure Legends from Gemcitabine Mechanism of Action Confounds Early Assessment of Treatment Response by 3′-Deoxy-3′-[<sup>18</sup>F]Fluorothymidine in Preclinical Models of Lung Cancer (2023)

&lt;p&gt;Legends for Supplementary Figures S1-S5&lt;/p&gt;
Possible Post‐Traumatic Focal Dystonia Associated with Tau Pathology Localized to Putamen‐Globus Pallidus (2018)

Post-traumatic dystonia could be associated with post-traumatic tau pathology formation. However, more cases are necessary to establish causality. The tau lesions found in the BG of this patient did not fit within CTE criteria. We hypothesize that due to the anatomo-histological characteristics of the BG, tau pathology associated with brain traumas produce histopathological patterns different from sulcal-tau pathology, which is the only tau pathology distribution currently accepted as pathognomonic of CTE.
MEMS disk resonator gyroscope with integrated analog front-end (2013)

We present a 2 mm diameter, 35 μm thick disk resonator gyro (DRG) fabricated in <111> silicon with integrated 0.35 μm CMOS analog front-end circuits in the Invensense NF process. This process incorporates a wafer-level vacuum seal, yielding a quality factor (Q) of 2800 at the DRG's 78 kHz resonance frequency. After performing electrostatic tuning to enable mode-matched operation, this DRG achieves a 63 μV/°/s sensitivity. Resonator vibration in the sense and drive axes is sensed using capacitive transduction, and amplified using a low-noise, on-chip integrated circuit. This allows the DRG to achieve Brownian noise-limited performance. The angle random walk (ARW) is measured to be 0.01 (˚/sec)/√Hz and the bias instability is 30 °/hr.
Realization of high efficiency in a plasma-assisted microwave source with two-dimensional electron motion (2002)

Conventional microwave sources utilize a strong axial magnetic field to guide an electron beam through an interaction region. A plasma-assisted slow wave microwave oscillator (Pasotron) can operate without an external magnetic field because the presence of ions neutralizes the space charge in the beam, permits the self-pinch forces to provide beam propagation, and allows for the radial motion of electrons under the action of transverse fields of the wave. While the inherent efficiency of conventional microwave sources with 1D electron flow is limited to 15%–20%, it is shown in this work that both the calculated and measured inherent efficiency of devices with 2D electron flow can be higher than 50%. Both in situ diagnostics and analysis confirmed that the enhanced efficiency is due to the fact that rf forces dominate the beam dynamics.
Genetic epidemiology of hypertension and cerebrovascular disease (2002)

The molecular understanding of the genes of cerebrovascular disease and hypertension may contribute to better development of new diagnosis and treatment. Under classical strategy, scientists have tried first to find a physiological phenomenon specific for essential hypertension, then to identify the protein underlying the physiological abnormality, and finally to clarify the causative gene which encoded the protein. On the other hand, under the reverse genetic approach, the correlation between hypertension and genetic abnormality is identified first, and then the pathogenesis is clarified-in reverse order. Therefore, it is not extraordinary for unexpected results to be obtained in the correlation between a gene and a disease, suggesting that this approach has a possibility to be a breakthrough in the chaos of the research of hypertension and cerebrovascular disease.
Thermal Guiding in Microchip Lasers (1991)

The oscillating mode in cw microchip lasers is a thermally guided mode. In Nd:YAG microchip lasers the diameter of the oscillating mode is typically much larger than the pump diameter, resulting in a low-divergence, TEM00 beam which is insensitive to the transverse quality of the pump beam.
Parallel nonlinear optoelectronic image processing for real-time motion detection (1999)

An analog nonlinear optoelectronic image-processing system for detection of moving objects in an input image stream is proposed and analyzed. Its operation is based on the effect of self-suppression of a stationary-state image background, with enhancement of the contrast of a moving object. Analytical results obtained in the linear approximation are verified by direct numerical simulations. © 1999 Society of Photo-Optical Instrumentation Engineers. (S0091-3286(99)02203-5)
Design of dual-rate PID controllers (2002)

This paper is concerned with the computation of dual-rate high-order-hold PID discrete equivalent controllers. We assume that a continuous-time PID controller has been already designed in order to meet continuous time-domain and/or frequency-domain specifications. Based on the well-known lifting technique, dual-rate high-order-hold circuits and discrete equivalent controllers are proposed. The dual-rate controller is obtained by combining a dual-rate high-order-hold with two single-rate controllers, one at high frequency and the other at low frequency. They are related to the PD and PI action respectively. The effectiveness of the dual-rate sampling can be easily studied a priori at single-rate low frequency (constrained frequency) by analyzing its effects on the system when the ratio between sampling frequencies goes to infinity. An application example is presented.
CEREBRAL CO2-REACTIVITY AND AUTOREGULATION ARE INTACT DURING PROPOFOL-INDUCED EEG SUPPRESSION (1994)

Matta, B F MB, FRCA; Lam, A M MD, FRCPC; Strebel, S MD; Mayberg, T S MD Author Information
Figure S6 from <i>SLC43A3</i> Is a Biomarker of Sensitivity to the Telomeric DNA Damage Mediator 6-Thio-2′-Deoxyguanosine (2023)

&lt;p&gt;Supplementary Data 6&lt;/p&gt;
Cyano[tri(cyclohexyl)phosphino]gold(I), [Au(CN){(C6H11)3P}] (1997)

A linear complex of gold(I) cyanide with tri(cyclohexyl)phosphine, [Au(CN)(C18H33P)], has been synthesized and characterized by X-ray crystallographic analysis. Contrary to the ionic species formed with tri(2-cyanoethyl)phosphine, no ionic complex was formed in the case of tri(cyclohexyl)phosphine. The Au—C and Au—P distances of 2.006 (11) and 2.287 (3) Å, respectively, are similar to the corresponding distances in AuCN complexes of other tri(alkyl/aryl)phosphines.
Comparative Efficacy of 5-Methoxymethyl-2’-Deoxyuridine, 9<i>β</i>-<i>D</i>-Arabinofuranosyladenine and 5-Iodo-2’-Deoxyuridine in the Treatment of Experimental Herpes Simplex Keratitis (1980)

The relative efficacy of 5-methoxymethyldeoxyuridine (MMUdR), adenine arabinoside (Ara-A), 5-iododeoxyuridine (IUdR) and the combination of MMUdR and Ara-A in the treatment of experimental herpes simplex keratitis was investigated in rabbits. Treatment was initiated either at 4 or 24 h post virus inoculation. The parameter used to evaluate effectiveness was lesion size. Each eye was graded daily for the first 5 days and on alternate days thereafter to day 11. At concentrations of 2 or 5% both MMUdR and Ara-A were found to have potent antikeratitis activity. At 5% concentration, Ara-A provided essentially the same protection against herpes keratitis as 0.1% IUdR, while MMUdR was slightly less effective. The simultaneous application of 2% MMUdR and 2% Ara-A in combination was more effective than 5% MMUdR alone and was effective as 5% Ara-A or 0.1% IUdR in controlling the viral keratitis.
Dry Cask Storage Inspection and Monitoring. Interim Report. (2014)

Recently, the U.S. Nuclear Regulatory Commission (NRC) issued the guidance on the aging management of dry storage facilities that indicates the necessity to monitor the conditions of dry cask storage systems (DCSSs) over extended periods of time.1 Part of the justification of the aging management plans is the requirement for inspection and monitoring to verify whether continued monitoring, inspection or mitigation are necessary. To meet this challenge Argonne National Laboratory (ANL) in collaboration with Idaho National Laboratory (INL) is conducting scoping studies on current and emerging nondestructive evaluation/examination (NDE) and online monitoring (OLM) technologies for DCSS integrity assessments. The scope of work plan includes identification and verification of technologies for long-term online monitoring of DCSSs’ crucial physical parameters such as temperature, pressure, leakage and structural integrity in general. Modifications have been made to the current technologies to accommodate field inspections and monitoring. A summary of the scoping studies and experimental efforts conducted to date as well as plans for future activities is provided below.
Characterization of integrated Bragg gratings on silicon-on-insulator rib waveguides (2003)

Waveguide based Bragg grating devices have the potential of integration with passive or active optical components. A narrow bandwidth Bragg reflection filter or Fabry-Perot resonant structures can be realised using the approach of periodic refractive index modulation in waveguide gratings to form reflective structures. Most authors have considered 1st order Bragg gratings with periods of the order of 228nm operating at 1550nm but at the expense of complexity and high cost of fabrication. This paper describes the design of Silicon-On-Insulator (SOI) rib waveguides operating in the single mode regime that exhibit low polarisation dependence. A rigorous leaky mode propagation method (LMP) has been used to investigate the influence of etch depth in 3<sup>rd</sup> order Bragg gratings on the reflectance and bandwidth in the waveguides.
Impact of a disease-management program on symptom burden and health-related quality of life in patients with idiopathic pulmonary fibrosis and their care partners (2020)

Patients were recruited from the Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, located within the University of Pittsburgh Medical Center. Idiopathic pulmonary fibrosis results in scarring of the lung and respiratory failure, and has a median survival of 3 to 5 years from the time of diagnosis. The purpose of this study was to determine whether patients with idiopathic pulmonary fibrosis and their care partners could be more optimally managed by a disease-management intervention entitled “Program to Reduce Idiopathic Pulmonary Fibrosis Symptoms and Improve Management,” which nurses delivered using the format of a support group. We hypothesized that participation would improve perceptions of health-related quality of life (HRQoL) and decrease symptom burden.
Evidence for a “Carbene‐like” Intermediate during the Reaction of Methoxy Species with Light Alkenes on H‐ZSM‐5 (2011)

Geheimnis gelüftet: Mit IR-Spektroskopie wurde gefunden, dass die sauren Hydroxygruppen, die nach der Reaktion von [D3]Methoxygruppen mit leichten Alkenen an Zeolithen nachgewiesen werden, alle deuteriert sind (siehe Schema). Dies weist darauf hin, dass die Reaktion über Methylen-, nicht etwa über Methyl-Zwischenstufen verläuft.
Characterization of 6.5 kV IGBTs for High-Power Medium-Frequency Soft-Switched Applications (2013)

Medium voltage high-power applications are usually realized using high voltage semiconductors (3.3 kV and above) operated in the hard switching mode with low switching frequencies (several hundreds of hertz). However, for high-power dc-dc converters employing a transformer for galvanic isolation, it is attractive to increase the switching frequency so that the transformer size can be reduced. An increase of the switching frequency implies an increase of the switching losses, and this has to be mitigated somehow, usually by choice of resonant topologies or soft switching techniques. Main focus of the paper is on the operation of the insulated gate bipolar transistor (IGBT) within a high-power dc-dc LLC resonant converter, in order to explore interactions between semiconductor and circuit properties, which both must be simultaneously considered in order to achieve the best utilization of a high voltage power semiconductor operating at higher switching frequencies. For these purposes, switching properties of a standard 6.5 kV IGBT are compared with switching properties of two different optimized versions of a 6.5 kV IGBT. Experimental results are included to support theoretical considerations and findings.
Analysis of pilot symbol assisted modulation (PSAM) systems with power control and diversity (2003)

Pilot symbol assisted modulation schemes are used on fading channels to enable coherent demodulation at the receiver. Furthermore, diversity receivers (such as RAKE receivers) are used to combat the effects of fading. Higher orders of diversity result in greater protection against fading but, for the same total received energy, lower the quality of the channel estimates. This tradeoff in diversity order for pilot symbol-based schemes is captured analytically in the bit-error probability expressions derived in this paper. The higher the signal-to-noise ratio, the larger is the optimum diversity order. Results are then extended to the case with power control. Power control works to mitigate the fading and the tradeoff tilts in favor of using lower orders of diversity. The optimum diversity order depends strongly on the extent of averaging used to obtain the channel estimates and the proportion of the total energy assigned to the pilot symbols.
Orthogonal tributary channel exchange of 160-Gbit/s pol-muxed DPSK signal (2010)

We report the orthogonal tributary channel exchange of a polarization-multiplexed (pol-muxed) differential phase-shift keying (DPSK) optical time-division multiplexed (OTDM) signal by exploiting the Kerr effect-induced nonlinear birefringence in a highly nonlinear fiber (HNLF). We first implement Kerr effect-based 40-to-10, 80-to-10, and 160-to-10 Gbit/s demultiplexing of DPSK OTDM signals with power penalties of less than 0.5, 1.5, and 2.6 dB, respectively, at a bit-error rate (BER) of 10(-9). We further demonstrate 10-Gbit/s tributary channel exchange between two orthogonal polarizations of a 160-Gbit/s pol-muxed DPSK OTDM signal with a power penalty of less than 4 dB at a BER of 10(-9). Moreover, Jones matrix analyses are applied to the orthogonal polarization exchange, indicating the exchange condition of orthogonal polarization exchange with the characteristic of transparency to the modulation format. The exchange performance is analyzed in terms of the extinction ratio (ER) of the newly converted signal to the original residual signal. The dynamic range of the product of nonlinear coefficient, pump power, and effective fiber length, the dynamic range of pump power, the impact and tolerance of pump polarization offset are discussed to characterize and optimize the performance of orthogonal polarization exchange.