gebhart/patrepeval huggingface dataset:
Rapid Identification of Stacking Orientation in Isotopically Labeled Chemical-Vapor Grown Bilayer Graphene by Raman Spectroscopy (2013)

The growth of large-area bilayer graphene has been of technological importance for graphene electronics. The successful application of graphene bilayers critically relies on the precise control of the stacking orientation, which determines both electronic and vibrational properties of the bilayer system. Toward this goal, an effective characterization method is critically needed to allow researchers to easily distinguish the bilayer stacking orientation (i.e., AB stacked or turbostratic). In this work, we developed such a method to provide facile identification of the stacking orientation by isotope labeling. Raman spectroscopy of these isotopically labeled bilayer samples shows a clear signature associated with AB stacking between layers, enabling rapid differentiation between turbostratic and AB-stacked bilayer regions. Using this method, we were able to characterize the stacking orientation in bilayer graphene grown through Low Pressure Chemical Vapor Deposition (LPCVD) with enclosed Cu foils, achieving almost 70% AB-stacked bilayer graphene. Furthermore, by combining surface sensitive fluorination with such hybrid (12)C/(13)C bilayer samples, we are able to identify that the second layer grows underneath the first-grown layer, which is similar to a recently reported observation.
g-Values as a Probe of the Local Protein Environment: High-Field EPR of Tyrosyl Radicals in Ribonucleotide Reductase and Photosystem II (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTg-Values as a Probe of the Local Protein Environment: High-Field EPR of Tyrosyl Radicals in Ribonucleotide Reductase and Photosystem IISun Un, Mohamed Atta, Marc Fontecave, and A. William RutherfordCite this: J. Am. Chem. Soc. 1995, 117, 43, 10713–10719Publication Date (Print):November 1, 1995Publication History Published online1 May 2002Published inissue 1 November 1995https://pubs.acs.org/doi/10.1021/ja00148a013https://doi.org/10.1021/ja00148a013research-articleACS PublicationsRequest reuse permissionsArticle Views386Altmetric-Citations142LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Inter-operator spectrum sharing strategy for local area indoor dense deployment scenario (2014)

This paper investigates the inter-operator spectrum sharing problem in the local area indoor dense deployment scenario. A system framework is designed and function of each entity is discussed for solving this problem. Also a spectrum sharing strategy is developed based on the proposed architecture. This strategy improves the spectrum efficiency by offering each femtocell the opportunity to use the whole spectrum resources. Interference is controlled by graph theory-based intra operator spectrum allocation and Signal to Interference plus Noise Ratio (SINR) threshold-based inter-operator spectrum coordination. Intensive system level simulations give a detailed verification of the performance of this spectrum sharing strategy.
Evaluation of Two Methods for Quantification of Glycosaminoglycan Biomarkers in Newborn Dried Blood Spots from Patients with Severe and Attenuated Mucopolysaccharidosis Type II (2022)

All newborn screening (NBS) for mucopolysaccharidosis-I and -II (MPS-I and MPS-II) is carried out via the measurement of α-iduronidase (IDUA) and iduronate-2-sulfatase (IDS) enzymatic activity, respectively, in dried blood spots (DBS). The majority of low enzyme results are due to pseudodeficiencies, and data from recent MPS-II population screenings and studies from the Mayo Clinic show that the false positive rate can be dramatically reduced by the inclusion of a second-tier analysis of glycosaminoglycans (GAGs) in DBS as part of NBS. In the present study, which focused on MPS-II, we obtained newborn DBS from 17 patients with severe MPS-II, 1 with attenuated MPS-II, and 6 patients with various IDS pseudodeficiencies. These samples were submitted to two different GAG mass spectrometry analyses in a comparative study: (1) internal disaccharide biomarkers and (2) endogenous biomarkers. For both of these methods, the biomarker levels in six patients with pseudodeficiencies were below the range measured in MPS-II patients. One patient with attenuated MPS-II was not distinguishable from severe disease patients, but all MPS-II patients were distinguishable from the reference range using both methods. The minimal differential factor (lowest GAG marker level in MPS-II samples divided by highest level in the reference range of 60 random newborns) was 3.01-fold for the internal disaccharide method. The endogenous biomarker method demonstrated an improved minimum differential of 5.41-fold. The minimum differential factors between MPS-II patients and patients with pseudodeficiencies for the internal disaccharide and endogenous biomarker methods were 3.77-fold and 2.06-fold, respectively. This study supports use of the second-tier GAG analysis of newborn DBS, especially the endogenous disaccharide method, as part of NBS to reduce the false positive rate.
Demonstration of universal time-reversal for qubit processes (2022)

Experimental dataset for "Demonstration of universal time-reversal for qubit processes" (arxiv:2205.01122)
Gallic acid attenuates blood-spinal cord barrier disruption by inhibiting Jmjd3 expression and activation after spinal cord injury (2020)

After spinal cord injury (SCI), blood-spinal cord barrier (BSCB) disruption results in secondary injury including apoptotic cell death of neurons and oligodendrocytes, thereby leads to permanent neurological deficits. Recently, we reported that the histone H3K27me3 demethylase Jmjd3 plays a role in regulating BSCB integrity after SCI. Here, we investigated whether gallic acid (GA), a natural phenolic compound that is known to be anti-inflammatory, regulates Jmjd3 expression and activation, thereby attenuates BSCB disruption following the inflammatory response and improves functional recovery after SCI. Rats were contused at T9 and treated with GA (50 mg/kg) via intraperitoneal injection immediately, 6 h and 12 h after SCI, and further treated for 7 d with the same dose once a day. To elucidate the underlying mechanism, we evaluated Jmjd3 activity and expression, and assessed BSCB permeability by Evans blue assay after SCI. GA significantly inhibited Jmjd3 expression and activation after injury both in vitro and in vivo. GA also attenuated the expression and activation of matrix metalloprotease-9, which is well known to disrupt the BSCB after SCI. Consistent with these findings, GA attenuated BSCB disruption and reduced the infiltration of neutrophils and macrophages compared with the vehicle control. Finally, GA significantly alleviated apoptotic cell death of neurons and oligodendrocytes and improved behavior functions. Based on these data, we propose that GA can exert a neuroprotective effect by inhibiting Jmjd3 activity and expression followed the downregulation of matrix metalloprotease-9, eventually attenuating BSCB disruption after SCI.
Mission Assurance for Autonomous Undersea Vehicles (2020)

Autonomous vehicles are all but inevitable, and assurance that they will behave safely with respect to passengers, as well as bystanders incidentally exposed to them, is moving forward, albeit slowly. The state of the art often involves stopping the vehicle, perhaps after diverting it to a nearby safe place. While this is good news, it does not fully realize the benefits of autonomy. Autonomous vehicles are built for a purpose; call it a mission. Being able to perform the mission, or part of it, while experiencing faults (or cyber-attack) should be a factor in determining the vehicle's suitability for the mission. This paper explores the state of the art in achieving autonomous mission assurance in the context of autonomous undersea vehicles (AUVs). It identifies gaps in the literature and proposes a novel plan to address certain gaps.
Heteroleptic Copper Dipyrromethene Complexes:  Synthesis, Structure, and Coordination Polymers (2004)

The synthesis of neutral [Cu(dpm)2] and [Cu(dpm)(acac)] (dpm = dipyrromethene, acac = acetylacetonato) complexes is presented. The formation of the asymmetric metal complexes was monitored by electronic absorption and infrared spectroscopy. Two of the complexes investigated, containing pyrdpm ligands (pyrdpm = pyridyldipyrromethene), form 1-dimensional coordination polymers. The coordination polymers formed by these complexes have been characterized by single-crystal X-ray diffraction, differential scanning calorimetry, and thermogravimetric analysis. The complexes possess square pyramidal coordination geometries with the apical position occupied by the meso-pyridyl donor of a neighboring complex in the crystal lattice. The features of these coordination complexes that facilitate formation of extended solids have been probed. Symmetric [Cu(pyrdpm)2] complexes are unable to form coordination solids due to steric hindrance at the metal center. Use of cyano donors in complexes such as [Cu(cydpm)(acac)] (cydpm = cyanodipyrromethene) in lieu of pyridyl donors also fail to form network solids. Through these systematic studies, both the basic coordination chemistry of these complexes and the fundamental design requirements for synthesizing this novel class of coordination polymers have been defined.
Supplementary Table 2 from Overall Survival in Malignant Glioma Is Significantly Prolonged by Neurosurgical Delivery of Etoposide and Temozolomide from a Thermo-Responsive Biodegradable Paste (2023)

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Lateral, Ge, nanowire growth on SiO2 (2011)

Vapor-liquid-solid (VLS) nanowires (NWs) typically grow in [111] directions. Previously, the authors have demonstrated guided Si NW growth, engineering the VLS NWs to grow in a [110] direction against a SiO(2) surface. In this work, the authors demonstrate guided high-quality Ge nanowire growth against a SiO(2) surface in the substrate plane to bridge between two Si mesas. The authors explore the interfaces between a Ge NW and the two Si device-layer mesas and report high-quality, epitaxial interfaces between the Ge NW and both Si mesas.
Induction of cytolytic cells by pure recombinant human interleukin 2 (1984)

Purified recombinant human interleukin 2, produced in Escherichia coli, was sufficient to generate cytolytic cells in concanavalin A-stimulated, T helper cell-depleted (Lyt-1.1-) or accessory cell-depleted (Ia-) murine spleen cell cultures. Moreover, recombinant interleukin 2 (rIL2) was able (even at 0.5 ng/ml) to induce cytolytic cells in undepleted murine spleen cell cultures and undepleted human peripheral blood lymphocyte cultures in the absence of a mitogen. Purified recombinant human interferon-gamma, produced in Chinese hamster ovary cells, did not induce either cytolytic activity or IL2 responsiveness in human peripheral blood lymphocyte cultures. Possibly, the rIL2-induced cytolytic cells are formed as a result of nonspecific secondary cytotoxic T lymphocyte activation.
New approaches to catalytic C-H and C-C bond cleavage with Ruthenium complexes (2004)

The first part of the presented work deals with the synthesis and the characterization of the complexes [(IMes)Ru(H2)2(H)2(PCy3)] (1), [(IMes)2Ru(H2)2(H)2] (2) and its nitrogen derivative [(IMes)2Ru(H2)(N2)(H)2] (3) (IMes = 1,3-dimesityl-1,3-dihydro-2H-imidazol-2-ylidene). All the ruthenium complexes have been obtained in crystalline form, thus allowing a full characterization of their structure by NMR techniques and by X-ray analysis. Complex 1 exhibits a unique reactivity pattern for intra- and inter-molecular activation of C-H bonds (H/D exchange, Murai reaction, hydrogenation of C=O and CN bonds). The second part of the work presented in the thesis focus on the olefin metathesis catalyzed by Grubbs catalyst [RuCl2(=CHPh)(PCy3)2] (4) successfully carried out in ionic liquid such as [emim][Tf2N] (1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide). The products can be isolated by extraction with common organic solvents such as pentane or with scCO2.
Topology and mutational analysis of the single Emb arabinofuranosyltransferase of Corynebacterium glutamicum as a model of Emb proteins of Mycobacterium tuberculosis (2006)

The cell wall mycolyl-arabinogalactan (AG)--peptidoglycan complex is essential in mycobacterial species, such as Mycobacterium tuberculosis, and is the target of several antitubercular drugs. For instance, ethambutol (EMB) targets AG biosynthesis through inhibition of the arabinofuranosyltransferases Mt-EmbA and Mt-EmbB, as well as the single Emb from Corynebacterium glutamicum. Here, we present for the first time an experimental analysis of the membrane topology of Emb. The domain organization clearly positions highly conserved loop regions, like the recognized glycosyltransferase C motif and the hydrophilic C-terminus towards the periplasmic side of the cell. Moreover, the assignment and orientation of hydrophobic segments identified a loop region, which might dip into the membrane and could possibly line a transportation channel for the emerging substrate. Site-directed mutations introduced into plasmid-encoded Cg-emb were analyzed in a C. glutamicumDeltaemb strain for their AG glycosyl composition and linkage analysis. Mutations analyzed did not perturb galactan synthesis; however, D297A produced a dramatically reduced arabinan content and prevented growth, indicating an inactive Emb. A second D298A mutation also drastically reduced arabinan content; however, growth of the corresponding mutant was not altered, indicating a certain tolerance of this mutation in terms of Emb function. A W659L-P667A-Q674E triple mutation in the chain length regulation motif (Pro-motif) resulted in a reduced arabinose deposition in AG but retained all arabinofuranosyl linkages. Taken together, the data clearly define important residues of Emb involved in arabinan domain formation and, for the first time, shed new light on the topology of this important enzyme.
Nonlinear load characteristics of HVDC converters (2016)

The voltage dependence of HVDC (High Voltage Direct Current) converters as a load in ac systems is studied in this paper. Analytical studies are conducted for various HVDC control modes. It is shown that HVDC converter behaves between constant power and constant current. Its reactive power is more close to constant current type load. It is also demonstrated that the unfavorable load voltage relationship was mainly caused by the large amount of capacitive compensation at the converter bus. In fact, those capacitors play more role than the converters themselves in driving the connected ac system to be vulnerable to voltage instability.
Effect of Statewide Lockdown in Response to COVID-19 Pandemic on Physical Activity Levels of Hemodialysis Patients (2021)

Lockdown measures were associated with a significant decrease in PAL in hemodialysis patients. Patients who contracted COVID-19 had higher PAL during the incubation period. Methods to increase PAL while allowing for social distancing should be explored and implemented.
Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the α2β1-integrin receptor (2006)

Endorepellin, a C-terminal fragment of the vascular basement membrane proteoglycan perlecan, inhibits angiogenesis via the alpha2beta1-integrin receptor. Because this integrin is also implicated in platelet-collagen responses and because endorepellin or its fragments are generated in response to injury and inflammation, we hypothesized that endorepellin could also affect platelet biology. We discovered that endorepellin supported alpha2beta1-dependent platelet adhesion, without appreciably activating or aggregating platelets. Notably, endorepellin enhanced collagen-evoked responses in platelets, in a src kinase-dependent fashion, and enhanced the collagen-inhibitory effect of an alpha2beta1-integrin function-blocking antibody. Collectively, these results suggest that endorepellin/alpha2beta1-integrin interaction and effects are specific and dependent on cell type, differ from those emanated by exposure to collagen, and may be due to cellular differences in alpha2beta1-integrin activation/ligand affinity state. These studies also suggest a heretofore unrecognized role for angiostatic basement membrane fragments in platelet biology.
Tailoring the molecular structure to suppress extrinsic disorder in organic transistors (2013)

In organic field-effect transistors, the structure of the constituent molecules can be tailored to minimize the disorder experienced by charge carriers. Experiments on two perylene derivatives show that disorder can be suppressed by attaching longer core substituents - thereby reducing potential fluctuations in the transistor channel and increasing the mobility at low temperature - without altering the intrinsic transport properties.
A Main‐Chain de Vries Smectic Liquid Crystal Polymer Prepared by Hoveyda–Grubbs Catalyst Initiated Acyclic Diene Metathesis Polymerization (2009)

A main-chain liquid crystalline polymer has been obtained by applying a Hoveyda-Grubbs 2nd generation catalyst in acyclic diene metathesis polymerization (ADMET) of a monomer containing on one end a terminal dimethylvinylsilyl group and at the other end a terminal CC double bond. This material showed an interesting Iso-de Vries SmA* - SmC* - Glass phase transition with a very small layer shrinkage on progressing from the SmA* phase into the SmC* phase. Will this material present a helical structure along the fiber axis in the SmC* temperature range? Several physical characterization methods including XRD, optical observation, and microtome technique have been used to investigate the internal structural organization in this liquid crystalline fiber.
Acoustic Detection of Leaks in Water Pipelines Using Measurements inside Pipe (2011)

Acoustic leak-detection techniques are proven to be effective and have been widely used in water-distribution systems for several decades. Most of the existing acoustic leak-detection techniques rely on external measurements of sound emitted from the turbulent jet of water escaping the pipe. Direct acoustic measurements through hydrophones, which travel inside the pipe with the flow, have been recently addressed as an efficient complementary leak-detection technique. This paper presents an experimental investigation that addresses the feasibility and potential of in-pipe acoustic measurements for leak detection. An experimental test rig was constructed to simulate a water transmission pipeline and permits different leak sizes, flow rates, and pressures. The acquired acoustic signals were analyzed; the feasibility and limitations of invoking in-pipe measurements for leak detection were addressed.
ChemInform Abstract: Structure of Sodium Tellurite Glasses: Sodium Cation Environments from Sodium‐23 NMR. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Impact of specific failure mechanisms on endurance improvement for HfO<inf>2</inf>-based ferroelectric tunnel junction memory (2018)

We conducted a detailed investigation on failure mechanisms for the HfÖ2-based ferroelectric tunnel junction (FTJ) memory during set/reset cycling endurance by combining methodology of the well-known reliability evaluation (time-dependent dielectric breakdown (TDDB)) and the memory-specific evaluation (cycling endurance). As a consequence, we clarify that an increase of stress induced leakage current (SILC) after cycling is the main cause of the failure and demonstrate the cycling endurance enhancement by suppressing the SILC with optimizing the measurement sequence. Based on these results, we show a potential to achieve 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">6</sup> cycles.
Complex IF Harmonic Rejection Mixer for Non-Contiguous Dual Carrier Reception in 65 nm CMOS (2013)

This paper presents a complex IF mixer for a double conversion receiver architecture to be used for non-contiguous dual carrier reception as specified in upcoming releases of 3GPP standards. The complex IF mixer contains four harmonic rejection (HR) mixers, each of which is implemented with 64 passive unit cell mixers, clocked by a ring-oscillator based phase-locked loop and driven by sequencers that represent thermometer-coded oversampled sinusoidal LO waveforms. Each HR mixer is followed by a buffer and a signal distribution network to enable separation of the two carriers as well as IQ-imbalance correction. The complex IF mixer supports reception of two carriers with up to 65 MHz separation using 12 samples per IF LO period and a clock frequency of 390 MHz. The IF mixer is implemented in 65 nm CMOS, has an area of 0.74 mm <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$^{2}$</tex></formula> , draws 26 mA, and has a harmonic conversion lower than <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex Notation="TeX">${-}68$</tex></formula> dBc per harmonic.
Enhancing the Antibiofilm Activity of β-1,3-Glucanase-Functionalized Nanoparticles Loaded With Amphotericin B Against Candida albicans Biofilm (2022)

<i>Candida</i> biofilm-related infections cause increased morbidity and mortality in patients with a reduced immune response. Traditional antifungal therapies have proven to be insufficient as the biofilm matrix acts as a perfusion barrier. Thus, novel methods are required to improve drug delivery and kill <i>Candida</i> within the biofilm. In this study, chitosan nanoparticles (CSNPs) loaded with Amphotericin B (AMB), which were functionalized with β-1,3-glucanase (Gls), were fabricated (CSNPs-AMB-Gls), and their antibiofilm activity against <i>Candida albicans</i> biofilm was evaluated <i>in vitro</i>. Scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM) were employed to examine biofilm architecture and cell viability. CSNPs-AMB-Gls inhibited planktonic cell growth and biofilm formation effectively and exhibited the highest efficacy on the removal of a mature biofilm than free AMB or CSNPs-AMB. The created nanoparticles (NPs) were found to penetrate the biofilm so as to directly interfere with the cells inside and disassemble the biofilm matrix. CSNPs-AMB-Gls could also eradicate biofilms from clinical isolates. These results suggest the potential applicability of CSNPs-AMB-Gls for the treatment of <i>Candida</i> biofilm-related infections.