gebhart/patrepeval huggingface dataset:
Cloud service placement via subgraph matching (2014)

Fast service placement, finding a set of nodes with enough free capacity of computation, storage, and network connectivity, is a routine task in daily cloud administration. In this work, we formulate this as a subgraph matching problem. Different from the traditional setting, including approximate and probabilistic graphs, subgraph matching on data-center networks has two unique properties. (1) Node/edge labels representing vacant CPU cycles and network bandwidth change rapidly, while the network topology varies little. (2) There is a partial order on node/edge labels. Basically, one needs to place service in nodes with enough free capacity. Existing graph indexing techniques have not considered very frequent label updates, and none of them supports partial order on numeric labels. Therefore, we resort to a new graph index framework, Gradin, to address both challenges. Gradin encodes subgraphs into multi-dimensional vectors and organizes them with indices such that it can efficiently search the matches of a query's subgraphs and combine them to form a full match. In particular, we analyze how the index parameters affect update and search performance with theoretical results. Moreover, a revised pruning algorithm is introduced to reduce unnecessary search during the combination of partial matches. Using both real and synthetic datasets, we demonstrate that Gradin outperforms the baseline approaches up to 10 times.
<title>Computed 3D models for very low bit-rate video coding</title> (2000)

This article deals with video sequence compression for very low bitrate. We assume static scene captured with a monocular moving camera. We propose a method using several 3D models in order to reconstruct the original video sequence or a virtual one. A complete scheme for video sequence compression is presented and compared with classical compression schemes.
F-1209 Joint Viscosity Design of Ankle Foot Orthosis (2001)

In this article, we examined the plantar flexion moment of hemiparetic patients as an important biomechanical index for design of ankle foot orthosis (AFO) from the viewpoint of ankle joint viscosity. Spastic ankle joint moment was measured with ankle joint angle by using a setup having single degree of freedom motion for dorsal-planter flexion axis with a torque transducer and a potentiometer. The observed spastic plantar flexion moments of a patient scattered largely depending on angular velocity of ankle joint motion. The rigidity under higher angular velocity exhibited much deviation of 45% in the maximum moment. Based on the measured spastic moment, switching viscosity was considered for at AFO joint to realize smooth gait motion for the subject preventing plantar flexion during swing phase and allowing it at the initial stance phase.
Cost Optimal Hybrid Communication Model for Smart Distribution Grid (2022)

There have been significant changes and dynamic growth in power grids since the inception of the smart grid. To ensure a self-sustainable grid, the power grid should facilitate the real-time sharing of the dynamic attributes of the power grid between the spatially distributed power grid elements. This demands a flawless design of the overlay communication network for a smart grid. However, instrumenting the entire grid with intelligent communication devices would be prohibitively expensive. A cost-optimal model is necessary to select the actual cardinality of intelligent communication devices required for the data transmission by ensuring its Quality of Service (QoS) metrics. This research work presents a smart distribution grid architecture with a network of microgrids and details the need for hybrid communication for intra-microgrid communication. A cost-optimal model is proposed to offer an optimal combination of technologies for intelligent devices in the hybrid communication overlay network. The formulation considers QoS metrics such as data packet latency, bandwidth requirement, link reliability, packet drops, and communication range of the technology to derive a cost-optimal solution. Based on this model, a Recursive Algorithm for Cost Optimal Combination of Communication Technology (RACOCCT) for a power grid topology is presented in this work. The simulation study performed on selected power grid topology based on the Standard IEEE 33 bus network reveals the cost-optimal combination of hybrid wireless communication technologies for the varying probability of link unreliability.
Estimating coupled harmonics in additive and multiplicative noise (2002)

Coupled harmonics indicate the presence of nonlinearities. Existing bispectral detectors of phase coupling in additive Gaussian noise are shown to require averaging over independent records, while single records are sufficient for frequency coupling. Novel bispectral and cyclic approaches are also derived for detection and estimation of phase and frequency coupled harmonics observed in stationary additive and multiplicative noise regardless of their distributions.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Amphipathic Barbiturates as Mimics of Antimicrobial Peptides and the Marine Natural Products Eusynstyelamides with Activity against Multi-resistant Clinical Isolates (2021)

We report a series of synthetic cationic amphipathic barbiturates inspired by the pharmacophore model of small antimicrobial peptides (AMPs) and the marine antimicrobials eusynstyelamides. These <i>N</i>,<i>N</i>'-dialkylated-5,5-disubstituted barbiturates consist of an achiral barbiturate scaffold with two cationic groups and two lipophilic side chains. Minimum inhibitory concentrations of 2-8 μg/mL were achieved against 30 multi-resistant clinical isolates of Gram-positive and Gram-negative bacteria, including isolates with extended spectrum β-lactamase-carbapenemase production. The guanidine barbiturate <b>7e</b> (3,5-di-Br) demonstrated promising <i>in vivo</i> antibiotic efficacy in mice infected with clinical isolates of <i>Escherichia coli</i> and <i>Klebsiella pneumoniae</i> using a neutropenic peritonitis model. Mode of action studies showed a strong membrane disrupting effect and was supported by nuclear magnetic resonance and molecular dynamics simulations. The results express how the pharmacophore model of small AMPs and the structure of the marine eusynstyelamides can be used to design highly potent lead peptidomimetics against multi-resistant bacteria.
Millimetre-waveguide-mounted InGaAs photodetectors (1986)

We describe the design and characteristics of InGaAs PIN photodetectors mounted in microwave waveguides for use in transmission of millimetre-wave modulation signals on optical carriers. For an experimental device operating to 60 GHz (5 mm wavelength), we show the wavelength dependence of responsivity, the spatial uniformity of response and the bias dependence of modulation bandwidth.
Practical efficiency limits in organic photovoltaic cells: Functional dependence of fill factor and external quantum efficiency (2009)

We evaluate practical power conversion efficiency limits (ηlim) in bulk-heterojunction organic photovoltaic (BHJ OPV) cells and how the field dependence of exciton dissociation affects cell efficiencies. We treat the fill factor limit as a function of the donor-acceptor lowest unoccupied molecular orbital offset energy (ELLO), calculating how this limit varies with decreasing ELLO. We also evaluate OPV external quantum efficiency as a function of wavelength from the optical transmittance and internal quantum efficiency limitations. For a given ELLO, we numerically optimize donor bandgap and ηlim and show that ηlim&amp;gt;10% should be possible for hypothetical OPV systems generating free charge carriers efficiently at ELLO∼0.3–0.4 eV. Current BHJ OPVs with low ELLO values appear to be limited to cell efficiencies of ∼5% largely as a consequence of incomplete exciton dissociation.
First documentation of adultTrichosirocalus horriduson several non-target nativeCirsiumspecies in Tennessee (2009)

Abstract Releases of Trichosirocalus horridus (Panzer) (Coleoptera: Curculionidae), native to Europe, began in Tennessee in 1989 as part of a biological control program against musk thistle (Carduus nutans L.). In surveys conducted to investigate non-target feeding of T. horridus on native Cirsium thistle species from 2005 to 2008, adults of T. horridus were observed on all five native Cirsium thistles. These adult occurrences are the first documentation of T. horridus occurring on three of these native species [C. carolinianum (Walt.) Fern & Schub., C. horridulum Michx. and C. muticum Michx.], and the first record of T. horridus occurring in the Great Smoky Mountains National Park. While C. carolinianum and C. horridulum did not show symptoms of larval feeding in the meristematic tissues, C. altissimum, C. discolor, and C. muticum all had damaged meristems and possible oviposition scars on the midribs of the leaves. However, the impact of feeding by larvae of T. horridus on the reproductive potential of native plants is uncertain, because even in the target species (musk thistle and other introduced Cirsium species) plant death only sometimes occurs, and seed production continues.
From Central Office Cloudification to Optical Network Disaggregation (2018)

The Cloud-based Central Office blurs the distinction between access, metro and data centre networks. We further show how this scenario provides new use cases for dynamic and disaggregated optical networking and new challenges that may be amenable to machine learning methods.
Yodel: A Yield Stress Model for Suspensions (2006)

A model for the yield stress of particulate suspensions is presented that incorporates microstructural parameters taking into account volume fraction of solids, particle size, particle size distribution, maximum packing, percolation threshold, and interparticle forces. The model relates the interparticle forces between particles of dissimilar size and the statistical distribution of particle pairs expected for measured or log‐normal size distributions. The model is tested on published data of sub‐micron ceramic suspensions and represents the measured data very well, over a wide range of volume fractions of solids. The model shows the variation of the yield stress of particulate suspensions to be inversely proportional to the particle diameter. Not all the parameters in the model could be directly evaluated; thus, two were used as adjustable variables: the maximum packing fraction and the minimum interparticle separation distance. The values for these two adjustable variables provided by the model are in good agreement with separate determinations of these parameters. This indicates that the model and the approximations used in its derivation capture the main parameters that influence the yield stress of particulate suspensions and should help us to better predict changes in the rheological properties of complex suspensions. The model predicts the variation of the yield stress of particulate suspensions to be inversely proportional to the particle diameter, but the experimental results do not show a clear dependence on diameter. This result is consistent with previous evaluations, which have shown significant variations in this dependence, and the reasons behind the yield stress dependence on particle size are discussed in the context of the radius of curvature of particles at contact.
Urinary nerve growth factor level could be a biomarker in the differential diagnosis of mixed urinary incontinence in women (2008)

The urinary NGF level could be a potential biomarker of DO in women with mixed UI.
The Immunomodulatory Effect of Sambucol on Leishmanial and Malarial Infections (2009)

A nontoxic dose of Sambucol, an immunomodulator commercially sold as an immune stimulator, was examined in murine models of leishmaniasis and malaria. Sambucol causes a shift in the immune response, as demonstrated in human monocyte cultures, to Th1 (inflammation-associated) responses. Treatment of leishmania-infected mice with Sambucol delayed the development of the disease. As there was no direct IN VITRO anti-leishmanial effect, the observed partial protection IN VIVO is most likely related to immune modulation. Although increased Th1 responses are associated with protection from leishmaniasis, they are considered to be the main immunopathological processes leading to cerebral malaria. Administration of Sambucol to mice prior to and following infection with Plasmodium berghei ANKA increased the incidence of cerebral malaria, while administration of Sambucol after infection had no effect on the disease. The results demonstrate how an inflammatory-like response may alleviate or exacerbate clinical symptoms of disease and hint at the importance of administration timing. The overall effect of immunomodulator administration depends on the ongoing immune response and the Th1/Th2 balance determined by both host and parasite defense mechanisms.
Survey on Symbiotic Radio: A Paradigm Shift in Spectrum Sharing and\n Coexistence (2021)

Sixth-generation (6G) of mobile communication aims to connect this world\ndigitally through green communication networks that provide secure, ubiquitous,\nand unlimited connectivity in an attempt to improve the overall quality of\nlife.The driving force behind the development of these networks is the rapid\nevolution of Internet-of-Things (IoT), which has stimulated the proliferation\nof wireless applications in health,education, agriculture, utilities, etc.\nHowever, these applications are accompanied by the deployment of a massive\nnumber of IoT devices that require a significant radio spectrum for wireless\nconnectivity. IoT devices usually have low data rate requirements and limited\npower provision but desirably a long life.Recently, the development of passive\nradio systems has opened new paradigms of spectrum sharing and coexistence.\nThese systems utilize the radio resources and infrastructure of the active\nradio systems to perform their functionalities. By enabling the dependent\ncoexistence, a new technology named symbiotic radio (SRad) enables the\nsymbiotic relationships between the different radio systems ranging from mutual\nbenefits or competition in terms of sharing the resources, in particular for\nIoT devices. This survey first provides the motivation for dependent\ncoexistence and background of spectrum sharing through coexistence along with\nexisting literature. Then, it describes the active and passive radio systems\ndefinition and a brief overview. Afterward, the history of symbiosis and the\nrole of SRad technology in spectrum sharing and coexistence are defined while\nfocusing on symbiotic communication. Lastly, we discuss research challenges,\nfuture directions, and applications scenarios.\n
1-Benzyl-2-(1H-indol-3-yl)-5-oxopyrrolidine-2-carbonitrile (2008)

In the title compound, C(20)H(17)N(3)O, a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse-transcriptase inhibitor, the pyrrolidine ring has an envelope conformation. In the crystal structure, adjacent mol-ecules are connected into infinite chains via an N-H⋯O hydrogen bond.
Endoleaks Following Endovascular Repair of Thoracic Aortic Aneurysm: Etiology and Outcomes (2008)

In this study, 1 in 5 TAA patients with TEVAR had endoleak. Most type I and III endoleaks required secondary intervention, while conservative treatment was most frequent for type II. Characterization of endoleak type was not always precise, and routine surveillance of all patients with endoleak is recommended.
Severe Acute Respiratory Syndrome Coronavirus Open Reading Frame (ORF) 3b, ORF 6, and Nucleocapsid Proteins Function as Interferon Antagonists (2020)

The severe acute respiratory syndrome coronavirus (SARS-CoV) is highly pathogenic in humans, with a death rate near 10%. This high pathogenicity suggests that SARS-CoV has developed mechanisms to overcome the host innate immune response. It has now been determined that SARS-CoV open reading frame (ORF) 3b, ORF 6, and N proteins antagonize interferon, a key component of the innate immune response. All three proteins inhibit the expression of beta interferon (IFN-β), and further examination revealed that these SARS-CoV proteins inhibit a key protein necessary for the expression of IFN-β, IRF-3. N protein dramatically inhibited expression from an NF-κB-responsive promoter. All three proteins were able to inhibit expression from an interferon-stimulated response element (ISRE) promoter after infection with Sendai virus, while only ORF 3b and ORF 6 proteins were able to inhibit expression from the ISRE promoter after treatment with interferon. This indicates that N protein inhibits only the synthesis of interferon, while ORF 3b and ORF 6 proteins inhibit both interferon synthesis and signaling. ORF 6 protein, but not ORF 3b or N protein, inhibited nuclear translocation but not phosphorylation of STAT1. Thus, it appears that these three interferon antagonists of SARS-CoV inhibit the interferon response by different mechanisms.
pH-Mediated Microbial and Metabolic Interactions in Fecal Enrichment Cultures (2017)

pH and fermentable substrates impose selective pressures on gut microbial communities and their metabolisms. We evaluated the relative contributions of pH, alkalinity, and substrate on microbial community structure, metabolism, and functional interactions using triplicate batch cultures started from fecal slurry and incubated with an initial pH of 6.0, 6.5, or 6.9 and 10 mM glucose, fructose, or cellobiose as the carbon substrate. We analyzed 16S rRNA gene sequences and fermentation products. Microbial diversity was driven by both pH and substrate type. Due to insufficient alkalinity, a drop in pH from 6.0 to ~4.5 clustered pH 6.0 cultures together and distant from pH 6.5 and 6.9 cultures, which experienced only small pH drops. Cellobiose yielded more acidity than alkalinity due to the amount of fermentable carbon, which moved cellobiose pH 6.5 cultures away from other pH 6.5 cultures. The impact of pH on microbial community structure was reflected by fermentative metabolism. Lactate accumulation occurred in pH 6.0 cultures, whereas propionate and acetate accumulations were observed in pH 6.5 and 6.9 cultures and independently from the type of substrate provided. Finally, pH had an impact on the interactions between lactate-producing and -consuming communities. Lactate-producing <i>Streptococcus</i> dominated pH 6.0 cultures, and acetate- and propionate-producing <i>Veillonella</i>, <i>Bacteroides</i>, and <i>Escherichia</i> dominated the cultures started at pH 6.5 and 6.9. Acid inhibition on lactate-consuming species led to lactate accumulation. Our results provide insights into pH-derived changes in fermenting microbiota and metabolisms in the human gut. <b>IMPORTANCE</b> The human gut is a dynamic environment in which microorganisms consistently interact with the host via their metabolic products. Some of the most important microbial metabolic products are fermentation products such as short-chain fatty acids. Production of these fermentation products and the prevalence of fermenting microbiota depend on pH, alkalinity, and available dietary sugars, but details about their metabolic interactions are unknown. Here, we show that, for <i>in vitro</i> conditions, pH was the strongest driver of microbial community structure and function and microbial and metabolic interactions among pH-sensitive fermentative species. The balance between bicarbonate alkalinity and formation of fatty acids by fermentation determined the pH, which controlled microbial community structure. Our results underscore the influence of pH balance on microbial function in diverse microbial ecosystems such as the human gut.
Measurement of the differential dijet production cross section in proton–proton collisions at s=7 TeV (2011)

A measurement of the double-differential inclusive dijet production cross section in proton-proton collisions at s = 7 TeV is presented as a function of the dijet invariant mass and jet rapidity. The data correspond to an integrated luminosity of 36 pb -1 , recorded with the CMS detector at the LHC. The measurement covers the dijet mass range 0.2 TeV to 3.5 TeV and jet rapidities up to |y| = 2.5. It is found to be in good agreement with next-to-leading-order QCD predictions.
A pharmacodynamic study of SR 47436, a selective AT1 receptor antagonist, on blood pressure in conscious cynomolgus monkeys (1994)

1. Conscious normotensive cynomolgus monkeys were chronically instrumented for the measurement of arterial blood pressure and heart rate to investigate the relationships between the plasma concentration, suppression of the pressor response to angiotensin II (AII), compensatory increase in plasma AII, and hypotensive effect obtained after a single oral dose of SR 47436, a potent and specific nonpeptide AT1 receptor antagonist. As blood sampling could influence the hypotensive effect of SR 47436 through activation of the renin angiotensin system (RAS), drug effects were studied in groups of animals with or without blood samplings. 2. SR 47436 at 10 mg kg-1 induced a hypotensive effect which was not greater following a second dose of 30 mg kg-1, indicating that a maximal hypotensive effect had already been obtained. 3. A single oral dose of SR 47436 (10 mg kg-1) caused a sustained hypotension and a marked inhibition of the AII-induced pressor response, lasting for up to 28 h. These effects of SR 47436 are consistent with good oral bioavailability and a slow elimination of the drug (t 1/2 approximately 20 h), and were accompanied by a sustained increase in plasma AII concentration. Taken together, both the hypotensive response and the compensatory increase in AII indicated that vascular and juxtaglomerular AII receptors were blocked. 4. Although a fair correlation between individual plasma drug concentrations and inhibition of AII-induced pressor response was observed, neither the hypotensive effect nor the compensatory increase in AII correlated with the plasma drug levels. 5. Basal arterial pressure and AII-induced pressor response were not affected by blood samplings. 6. These results suggest that SR 47436 is an effective and long lasting AT1 receptor antagonist with a potent hypotensive action in normotensive cynomolgus monkeys. It may be an efficacious blocker of the RAS in man and suitable for once-a-day dosing.
Chromosome-Sized DNA Molecules of Plasmodium falciparum (1985)

At least seven chromosome-sized DNA molecules (750 to 2000 kilobases in length and one fraction of undetermined molecular weight) from cultured clones and isolates of Plasmodium falciparum have been separated by pulsed-field gradient gel electrophoresis. Whereas asexual blood stages and sexual stages of the same line have identical molecular karyotypes, the length of chromosome-sized DNA molecules among different geographical isolates and several clones derived from a single patient is different. These length alterations of chromosomes are the result of DNA rearrangements that must occur unrelated to sexual differentiation.
P-type 6H-SiC photoconductive switches (1993)

Summary form only given. Photoconductive techniques were to measure both the surface and bulk carrier lifetimes in p-type 6H-SiC. In order to separate the surface and bulk material properties, both lateral and vertical switches were used. Measurements were made with both a N/sub 2/ laser and an N/sub 2/-pumped dye laser as the optical source, which permitted investigation of the switch behavior both above and just below the 6H-SiC absorption edge. The photovoltaic and photoconductive effects were measured for both switch geometries and at several wavelengths near the 6H-SiC absorption edge. Although the devices possess dark resistances on the order of 10 /spl Omega/, the switching efficiency of the vertical switches approached 32 percent, while the resistance of the lateral devices could be reduced by 50 percent with 200 /spl mu/J of laser radiation at /spl lambda/ = 337 nm.