gebhart/patrepeval huggingface dataset:
Effect of levitation forces on the performance of surface micromachined MEMS gyroscopes (2006)

In this paper, we study the effect of electrostatic levitation forces on the performance of a MEMS surface micromachined gyroscope. An error model relating the effects of the induced levitation deflections to scale factor and cross axis sensitivity is presented. Simulation and experimental results on a surface micromachined test structure are used to identify deflection versus voltage characteristics. These characteristics are scaled based on typical gyroscope parameters and the findings are that levitation forces can cause more than 50% reduction in scale factor and more than 0.1% increase in undesirable cross-axis sensitivity.
Modelling active sites for the Beckmann rearrangement reaction in boron-containing zeolites and their interaction with probe molecules (2010)

Theoretical calculations and in situ solid state NMR spectroscopy have been combined to get insight on the nature of the active sites for the Beckmann rearrangement reaction in borosilicate zeolites. The interaction of a B site in zeolite Beta with a series of probe molecules (ammonia, pyridine, acetone and water) has been modelled and the (15)N and (11)B NMR isotropic chemical shift of the resulting complexes calculated and compared with experimental in situ NMR results. This approach has allowed validation of the methodology to model the adsorption on a zeolite boron site of molecules of varying basicity which are either protonated or non-protonated. The limitation is that theoretical calculations overestimate the effect of molecular adsorption through hydrogen bonds on the calculated isotropic (11)B NMR chemical shift.Theoretical and experimental results on the adsorption of acetophenone and cyclohexanone oximes on zeolite B-Beta indicate that Brønsted acid sites protonate the oximes, changing the boron coordination from trigonal to tetrahedral. Comparison of theoretical and experimental (15)N NMR chemical shifts of the adsorbed amides (acetanilide and epsilon-caprolactam) indicates that they are non-protonated, and the (11)B NMR spectra show that, as expected, boron remains in trigonal coordination with an isotropic delta(11)B(exp) which differs from the calculated value delta(11)B(calc).
Comparative Immunocytochemical Localization of Corticotropin Releasing Factor (CRF-41) and Neurohypophysial Peptides in the Brain of Brattleboro and Long-Evans Rats (1983)

The localization of CRF-41 related peptide was studied in the brain and posterior pituitary of the homozygous rats for the inherited diabetes insipidus (Brattleboro strain, DI) and of the Long-Evans rats (LE) as control. It was compared to the distribution of vasopressin (AVP), oxytocin (OXY) and OXY-neurophysin (N I). In both strains, CRF-41 was identified in two morphologically distinct systems: one was a hypothalamoneurohypophysial system simultaneously containing CRF-41, OXY and N I; the other was a hypothalamoinfundibular system carrying CRF-41 only. CRF containing neurons were located in the periventricular area of the anterior hypothalamus, in the retrochiasmatic part of the supraoptic nuclei (SON) and, for some of them, in the antechiasmatic part of SON. CRF immunostainings were enhanced by colchicine treatment in LE rats and by DDAVP therapy in DI rats.
Ambient temperature anionic polymerization of methylmethacrylate by using alkyllithium/dimethylsulfoxide initiator system (2002)

peer reviewed
51.2: Outcoupling Enhancement Mechanism Investigation on Highly Efficient PIN OLEDs using Crystallizing Evaporation Processed Organic Outcoupling Layers (2012)

Abstract For highly efficient and stable white PIN OLED devices using evaporation processable outcoupling layers for efficiency enhancement details on the outcoupling mechanisms could be revealed. It was found that the use of crystallizing outcoupling enhancement layers gives rise to a corrugation of the reflective cathode, which allows for a strong reduction of the plasmon absorption losses. Based on a three‐unit white architecture, an efficiency of 60 lm/W at a brightness of 1,000 cd/m 2 could be achieved at a color of x,y = 0.470/0.429 with a T50 lifetime of 90,000 hours.
Localization of Sequences within the C-terminal Domain of the Cystic Fibrosis Transmembrane Conductance Regulator Which Impact Maturation and Stability (2001)

Some disease-associated truncations within the 100-residue domain C-terminal of the second nucleotide-binding domain destabilize the mature protein (Haardt, M., Benharouga, M., Lechardeur, D., Kartner, N., and Lukacs, G. L. (1999) J. Biol. Chem. 274, 21873-21877). We now have identified three short oligopeptide regions in the C-terminal domain which impact cystic fibrosis transmembrane conductance regulator (CFTR) maturation and stability in different ways. A highly conserved hydrophobic patch (region I) formed by residues 1413-1416 (FLVI) was found to be crucial for the stability of the mature protein. Nascent chain stability was severely decreased by shortening the protein by 81 amino acids (1400X). This accelerated degradation was sensitive to proteasome inhibitors but not influenced by brefeldin A, indicating that it occurred at the endoplasmic reticulum. The five residues at positions 1400 to 1404 (region II) normally maintain nascent CFTR stability in a positional rather than a sequence-specific manner. A third modulating region (III) constituted by residues 1390 to 1394 destabilizes the protein. Hence the nascent form regains stability on further truncation back to residues 1390 or 1380, permitting some degree of maturation and a low level of cyclic AMP-stimulated chloride channel activity at the cell surface. Thus while not absolutely essential, the C-terminal domain strongly modulates the biogenesis and maturation of CFTR.
5′-Terminus of Moloney Murine Leukemia Virus 35 S RNA Is m 7 G 5′ ppp 5′ GmpCp (1976)

The 5'-terminal sequence m(7)G(5') ppp(5') GmpCp was isolated from Moloney murine leukemia virus 35S RNA after digestion of (32)P-labeled RNA with RNases T1, T2, and A followed by pH 3.5 ionophoresis on DEAE paper.
The int-1 proto-oncogene products are glycoproteins that appear to enter the secretory pathway. (1987)

The int-1 proto-oncogene encodes a primary product of 370 amino acids, is normally expressed in mid-gestational embryos and adult testis, and is activated by proviral insertions during mammary carcinogenesis. Polyclonal and monoclonal antibodies directed against int-1-specific synthetic peptides immunoprecipitate up to five forms of int-1 protein, ranging in size from 36,000 to 44,000 Mr, from cell lines that express cloned int-1 DNA introduced by transfection or infection with retroviral vectors. Pulse-chase labeling experiments and glycosidase digestions suggested that the smallest of the int-1 proteins is the primary translation product lacking its signal peptide and that it is modified to produce the larger species of sequential glycosylation. Subcellular fractionations demonstrated that all immunoprecipitable forms of int-1 are mainly associated with membranes. int-1 proteins in crude microsomal preparations are resistant to proteolysis and extractable at elevated pH, suggesting that they are sequestered within cytoplasmic vesicles in a manner consistent with the behavior of secretory products. However, we were unable to identify secreted int-1 products in extracellular fluids.
Periprostatic venous androgen levels in a subset of patients with prostate cancer: An investigation into a novel role of testosterone in localized prostate cancer. (2020)

341 Background: While androgens drive prostate cancer (PCa), studies of systemic levels in eugonadal patients have not shown a relationship with development or progression of PCa. This study characterizes the relationship between systemic, local venous, and tissue androgen levels to understand the regulation and influence of androgens on localized PCa. Methods: Peripheral &amp; periprostatic venous blood &amp; prostate tissue were collected from patients undergoing radical prostatectomy (RP). Androgen levels (testosterone (T) and dihydrotestosterone (DHT)) were assessed by mass spectrometry. PCa grade and stage, PSA, prostate volume, and periprostatic vein diameter (PPVD) on MRI were recorded. A second cohort of patients undergoing just prostate MRI (non-surgical) was assessed to investigate the relationship between PPVD and disease severity. Results: Samples were collected from 176 patients. Analysis identified a subset of patients with elevated periprostatic T (ppT) relative to systemic T (sT) including 25% with ppT/sT &gt; 2, 14% with ppT/sT &gt; 4, and 7% with ppT/sT &gt; 10. Patients with ppT/sT &gt; 4 had supraphysiologic T levels in the periprostatic venous blood (mean 4223ng/mL). These patients also had higher than predicted levels of tissue T and DHT (tT/sT of 0.48 vs 0.24 (p = 0.004) and tDHT/sT of 7.31 vs 4.72 (p = 0.011)). In the surgical cohort, PPVD was increased in patients with elevated ppT/sT levels (5.8mm vs 3.7mm, p = 0.013). In the biopsy cohort (n = 200), increased PPVD was associated with an increased risk of diagnosis of PCa (4.39mm vs 3.43mm p = 0.006) and clinically significant PCa (4.35mm vs 3.43mm p = 0.01). Conclusions: In a subset of patients with PCa, periprostatic venous T levels were highly elevated compared to peripheral levels. Tissue T and DHT were also increased, and MRI demonstrated increased PPVD. We hypothesize that collateralization of venous drainage from the gonadal vein leads to both high local T and dilated veins. In a biopsy cohort, increased PPVD was associated with an increased risk of diagnosis of any and clinically significant PCa, suggesting that high periprostatic androgen levels may play a role in development of PCa.
Total Mechanical Unloading Minimizes Metabolic Demand of Left Ventricle and Dramatically Reduces Infarct Size in Myocardial Infarction (2016)

Total LVAD support that minimizes metabolic demand maximizes the benefit of LVAD in the treatment of acute myocardial infarction.
Mostly parallel garbage collection (1991)

We present a method for adapting garbage collectors designed to run sequentially with the client, so that they may run concurrently with it. We rely on virtual memory hardware to provide information about pages that have been updated or "dirtied" during a given period of time. This method has been used to construct a mostly parallel trace-and-sweep collector that exhibits very short pause times. Performance measurements are given.
Optical Design of Hyperspectral Two-dimensional Display and its Application (2011)

A system with the hyperspectral camera and display can reproduce spectral information of objects. With this technology, a gamut of the system covers a full color range, and it is possible to avoid observer metameric failure. In this presentation, we introduce a novel optical system of the two-dimensional hyperspectral display and propose a new method to examine the metameric failure of each individual. We modified a programmable light source to build a new type of hyperspectral display. The spectral components of the light were arbitrarily set by controlling a digital micromirror device (DMD). Seven-hundred-and-sixty-eight independent combinations of the monochromatic light, of which wavelength and intensity were selected by the horizontal direction of 1024 pixels of the DMD, were composed as a line image. And then the line image was scanned to form a two dimensional hyperspectral image. We performed a preliminary experiment using the one dimensional version of the display. We combined three monochromatic wavelength components to match white using a spectroradiometer. Three different wavelength combinations, RGB1: 450, 560, 600 nm, RGB2: 470, 560, 600 nm, and RGB3: 470, 570, 600 nm, were used. The subjects were asked to answer the order of the three RGB whites that resembled equal energy white (EEW) presented as a surround stimulus. At the same time, the subjects answered the magnitude of the difference between each RGB white and EEW. Seven color normal subjects (ages: 26 to 53) participated in the experiment. We found noticeable difference in the responses RGB1 among subjects. The younger subjects called the color green, while the older called it yellow or red. We speculate that the short wavelength components in RGB1 were absorbed by older crystalline lenses. This simple test shows a potential of our system as a useful tool for detecting absorption of the crystalline lens.
Life and Operating Range Extension of the BPT-4000 Qualification Model Hall Thruster (2006)

Following completion of the 5,600 hr qualification life test of the BPT-4000 4.5 kW Hall Thruster Propulsion System, NASA and Aerojet have undertaken efforts to extend the qualified operating range and lifetime of the thruster to support a wider range of NASA missions. The system was originally designed for orbit raising and stationkeeping applications on military and commercial geostationary satellites. As such, it was designed to operate over a range of power levels from 3 to 4.5 kW. Studies of robotic exploration applications have shown that the cost savings provided by utilizing commercial technology that can operate over a wider range of power levels provides significant mission benefits. The testing reported on here shows that the 4.5 kW thruster as designed has the capability to operate efficiently down to power levels as low as 1 kW. At the time of writing, the BPT-4000 qualification thruster and cathode have accumulated over 400 hr of operation between 1 to 2 kW with an additional 600 hr currently planned. The thruster has demonstrated no issues with longer duration operation at low power.
Transcriptional alterations in hereditary and sporadic nonfunctioning pancreatic neuroendocrine tumors according to genotype (2017)

Distinct mRNA expression patterns were identified in sporadic-associated, VHL-associated, and MEN1-associated NFPanNETs. The current results uncover new pathways involved in NFPanNETs that are subtype-specific and provide potential new diagnostic or therapeutic targets based on tumor subtype. Cancer 2018;124:636-47. © 2017 American Cancer Society.
Cell-mediated Catabolism of Aggrecan (1995)

A rat chondrosarcoma cell line and primary bovine chondrocytes have been used to study cell-mediated aggrecan catabolism. Addition of 1 microM retinoic acid to chondrosarcoma cultures resulted in aggrecan proteolysis with the release of greater than 90% of the cell layer aggrecan into the medium within 4 days. NH2-terminal sequencing of chondroitin sulfate-substituted catabolic products gave a single major NH2-terminal sequence of ARGNVILTXK, initiating at Ala374. This showed that the proteinase, commonly referred to as "aggrecanase," which cleaves the Glu373-Ala374 bond of the interglobular domain of aggrecan (Sandy, J. D., Neame, P. J., Boynton, R. E., and Flannery, C. R. (1990) J. Biol. Chem. 266, 8683-8685), is active in this cell system. Aggrecan G1 domain, generated by cleavage of the interglobular domain, was also liberated during catabolism and this was characterized with three antipeptide antisera. Anti-CDAGWL was used as a general probe for G1 domain. Anti-FVDIPEN was used to specifically detect G1 domain with COOH terminus of Asn341, the form which is readily generated by cleavage of aggrecan by a wide range of matrix metalloproteinases. Anti-NITEGE antiserum was used to specifically detect G1 domain with COOH terminus of Gln373, the form which is the expected product of "aggrecanase"-mediated cleavage of aggrecan. Western blot analysis indicated that a single form of G1 domain of about 60 kDa was formed. G1 domain of this size reacted with both anti-CDAGWL and anti-NITEGE but not with anti-FVDIPEN. Similar experiments with primary bovine chondrocyte cultures, treated with either retinoic acid or interleukin 1, showed that two forms of catabolic G1 domain, of about 62 and 66 kDa, were formed. Both of these forms reacted on Western blots with anti-CDAGWL and also with anti-NITEGE. It is suggested that cell-mediated catabolism of the aggrecan interglobular domain in these culture systems, whether promoted by retinoic acid or interleukin 1, primarily involves cleavage of the Glu373-Ala374 bond by aggrecanase. The accumulation of G1 domain with a COOH-terminal of Glu373 shows that such aggrecanase-mediated cleavage can occur independent of the cleavage of the Asn341-Phe342 bond by matrix metalloproteinases.
Low-pressure Cs-Ba discharge. II. Probe measurements (1995)

Experiments are performed using Langmuir probes to measure the plasma parameters in both steady-state and I-V modes in a low-pressure Cs-Ba diode. The data show that at low discharge currents the electron energy distribution function is nonMaxwellian due to the presence of an electron beam from the emitter. Also, the plasma properties were nonhomogeneous across the 1 mm diode gap; the electron temperature was 10%–15% higher and the plasma potential ∼1 V higher near the emitter, and the plasma density was a factor of three higher near the collector. The good agreement between calculations and experiment, in spite of the presence of the electron beam from the emitter, suggested that the beam electrons do not undergo collisions with Cs atoms in the gap. Experimental I-V curves showed the presence of two different thermal emission currents, each corresponding to a different emitter work function, at the beginning and the end of the I-V pulse.
On Post-Quantum Identification in 5G (2022)

We introduce PQ 5G AKA, a prototype for possible extensions of the current 5G authentication and key agreement protocol to the post-quantum setting, we further analyse the computational and communication complexities of our prototype using potential post-quantum KEMs
Att genomföra projekt - Två teoretiska perspektiv på ett problemfyllt projekt i ett kunskapsföretag (2001)

This thesis examines a project that has been conducted at a software development company. The aim is to investigate which problems firms of this kind faces performing projects. We choose a theoretical frame consisting of a modern view on how to manage projects. The view argues that the management of each project has to be adapted to the situation at hand. This theory is divided into two separate streams of reasoning; one emphasize learning, delegation of responsibility and flexibility, while the other argues for control, time planning and the importance of keeping to the plans. When we compare the theories to the case we draw three main conclusions: A thorough phase of investigation is required to produce the necessary planning documents. Further, flexibility is essential regarding the plans that have been made, thus if reality diverges from the plans they must be changed. Finally, care must be taken when consultants are involved in a project. It is then vital to work with them and manoeuvre their work process towards the goal of the project.
First certified reference material for cystatin C in human serum ERM-DA471/IFCC (2010)

The IFCC Working Group for the Standardisation of Cystatin C (WG-SCC), in collaboration with the Institute for Reference Materials and Measurements (IRMM), announces the availability of the new certified reference material ERM-DA471/IFCC. The material was characterised using a pure protein primary reference preparation (PRP) as calibrant. The PRP was prepared from recombinant cystatin C, and its concentration measured using dry mass determination. The characterisation of ERM-DA471/IFCC was performed by particle enhanced immuno-nephelometry, particle enhanced immuno-turbidimetry, and enzyme amplified single radial immuno-diffusion. The certified cystatin C mass concentration in ERM-DA471/IFCC, if reconstituted according to the specified procedure, is 5.48 mg/L, the expanded uncertainty (k=2) being 0.15 mg/L.
[Atrial fibrillation ablation in the real world]. (2010)

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in adults and is associated with significant morbidity and mortality. Medical treatment often fails to control symptoms and the limited success of drug therapy has incited clinical investigators to explore alternative treatments. Demonstration of focal pulmonary vein activity initiating AF in 1998 heralded a new era of "curative" AF ablation. Over the last years this strategy has been adopted in one form or another by the electrophysiologists worldwide and progressively applied to patients with structural heart disease as well as those with persistent and long-lasting AF. Catheter ablation for AF does not come without risk. Complications have been described in individual center experiences and have recently been summarized in the worldwide survey of AF, with the purpose to provide a survey on the methods, safety, and efficacy of curative catheter ablation of AF over a broader spectrum of electrophysiology laboratories. The encouraging results of AF ablation reported by highly specialized centers in selected subsets of patients are undisputed but long-term prospective randomized studies are warranted to better define the patient population that may derive the greatest benefit from ablation at the lowest risk and at an acceptable cost.
ChemInform Abstract: Concise Stereoselective Routes to Advanced Intermediates Related to Natural and Unnatural Pinnaic Acid. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Direct Patterning, Conformal Coating, and Erbium Doping of Luminescent nc‐Si/SiO2 Thin Films from Solution Processable Hydrogen Silsesquioxane (2007)

Hydrogen silsesquioxane is used as a solution-borne molecular precursor in the fabrication of highly luminescent thin films of SiO2 containing silicon nanocrystals. Films are readily formed on non-flat substrates (e.g., optical fibers) and patterned using e-beam lithography (see figure).
Role of CCK and potential utility of CCK1 receptor antagonism in the treatment of pancreatitis induced by biliary tract obstruction (2008)

The elevation of plasma amylase and lipase activity in the early stages of obstruction-induced pancreatitis is largely driven by elevation of plasma CCK concentration and activation of CCK1 receptors. These data show that CCK is an initiating factor in acute pancreatitis in the rat.
Challenges raised by long on-chip wiring for CMOS microprocessor applications (2002)

The unique characteristics of long on-chip interconnections in terms of modelling, simulation and design practices are investigated for representative five-layer structures. Experimental results are shown for a specially designed test vehicle with lines as long as 1.6 cm and line resistance of R=35 to 500 /spl Omega//cm.
Internal strains of magnetostrictive origin: Their nature in the static case and behavior in the dynamic regime (1981)

Any non uniformity in the spin direction distribution gives rise to internal stresses and strains in a magnetostrictive material. The stresses associated with wall junctions and by extension curved wall boundaries are analysed. It is shown that they are equivalent to the stresses characteristic of disclinations. In the dynamic regime, wall instabilities confined between lattice defects and wall junctions have been observed.