gebhart/patrepeval huggingface dataset:
GPU-Accelerated Partially Linear Multiuser Detection for 5G and Beyond URLLC Systems (2022)

In this feasibility study, we have implemented a recently proposed partially linear multiuser detection algorithm in reproducing kernel Hilbert spaces (RKHSs) on a GPU-accelerated platform. Partially linear multiuser detection, which combines the robustness of linear detection with the power of nonlinear methods, has been proposed for a massive connectivity scenario with the non-orthogonal multiple access (NOMA). This is a promising approach, but detecting payloads within a received orthogonal frequency-division multiplexing (OFDM) radio frame requires the execution of a large number of inner product operations, which are the main computational burden of the algorithm. Although inner-product operations consist of simple kernel evaluations, their vast number poses a challenge in ultra-low latency (ULL) applications, because the time needed for computing the inner products might exceed the sub-millisecond latency requirement. To address this problem, this study demonstrates the acceleration of the inner-product operations through massive parallelization. The result is a GPU-accelerated real-time OFDM receiver that enables sub-millisecond latency detection to meet the requirements of 5th generation (5G) and beyond ultra-reliable and low latency communications (URLLC) systems. Moreover, the parallelization and acceleration techniques explored and demonstrated in this study can be extended to many other signal processing algorithms in Hilbert spaces, such as those based on projection onto convex sets (POCS) and adaptive projected subgradient method (APSM) algorithms. Experimental results and comparisons with the state-of-art confirm the effectiveness of our techniques.
Realizability of iso-g2 processes via effective pair interactions (2022)

An outstanding problem in statistical mechanics is the determination of whether prescribed functional forms of the pair correlation function g<sub>2</sub>(r) [or equivalently, structure factor S(k)] at some number density ρ can be achieved by many-body systems in d-dimensional Euclidean space. The Zhang-Torquato conjecture states that any realizable set of pair statistics, whether from a nonequilibrium or equilibrium system, can be achieved by equilibrium systems involving up to two-body interactions. To further test this conjecture, we study the realizability problem of the nonequilibrium iso-g<sub>2</sub> process, i.e., the determination of density-dependent effective potentials that yield equilibrium states in which g<sub>2</sub> remains invariant for a positive range of densities. Using a precise inverse algorithm that determines effective potentials that match hypothesized functional forms of g<sub>2</sub>(r) for all r and S(k) for all k, we show that the unit-step function g<sub>2</sub>, which is the zero-density limit of the hard-sphere potential, is remarkably realizable up to the packing fraction ϕ = 0.49 for d = 1. For d = 2 and 3, it is realizable up to the maximum "terminal" packing fraction ϕ<sub>c</sub> = 1/2<sup>d</sup>, at which the systems are hyperuniform, implying that the explicitly known necessary conditions for realizability are sufficient up through ϕ<sub>c</sub>. For ϕ near but below ϕ<sub>c</sub>, the large-r behaviors of the effective potentials are given exactly by the functional forms exp[ - κ(ϕ)r] for d = 1, r<sup>-1/2</sup> exp[ - κ(ϕ)r] for d = 2, and r<sup>-1</sup> exp[ - κ(ϕ)r] (Yukawa form) for d = 3, where κ<sup>-1</sup>(ϕ) is a screening length, and for ϕ = ϕ<sub>c</sub>, the potentials at large r are given by the pure Coulomb forms in the respective dimensions as predicted by Torquato and Stillinger [Phys. Rev. E 68, 041113 (2003)]. We also find that the effective potential for the pair statistics of the 3D "ghost" random sequential addition at the maximum packing fraction ϕ<sub>c</sub> = 1/8 is much shorter ranged than that for the 3D unit-step function g<sub>2</sub> at ϕ<sub>c</sub>; thus, it does not constrain the realizability of the unit-step function g<sub>2</sub>. Our inverse methodology yields effective potentials for realizable targets, and, as expected, it does not reach convergence for a target that is known to be non-realizable, despite the fact that it satisfies all known explicit necessary conditions. Our findings demonstrate that exploring the iso-g<sub>2</sub> process via our inverse methodology is an effective and robust means to tackle the realizability problem and is expected to facilitate the design of novel nanoparticle systems with density-dependent effective potentials, including exotic hyperuniform states of matter.
Cyclopentane-modified PNA improves the sensitivity of nanoparticle-based scanometric DNA detection (2005)

trans-Cyclopentane-modified PNA has been successfully utilized as a target capture strand to improve the detection limit of a known DNA detection assay, and provide high levels of mismatch discrimination.
Comparison of computer-aided diagnosis performance and radiologist readings on the LIDC pulmonary nodule dataset (2008)

One challenge facing radiologists is the characterization of whether a pulmonary nodule detected in a CT scan is likely to be benign or malignant. We have developed an image processing and machine learning based computer-aided diagnosis (CADx) method to support such decisions by estimating the likelihood of malignancy of pulmonary nodules. The system computes 192 image features which are combined with patient age to comprise the feature pool. We constructed an ensemble of 1000 linear discriminant classifiers using 1000 feature subsets selected from the feature pool using a random subspace method. The classifiers were trained on a dataset of 125 pulmonary nodules. The individual classifier results were combined using a majority voting method to form an ensemble estimate of the likelihood of malignancy. Validation was performed on nodules in the Lung Imaging Database Consortium (LIDC) dataset for which radiologist interpretations were available. We performed calibration to reduce the differences in the internal operating points and spacing between radiologist rating and the CADx algorithm. Comparing radiologists with the CADx in assigning nodules into four malignancy categories, fair agreement was observed (&kappa;=0.381) while binary rating yielded an agreement of (&kappa;=0.475), suggesting that CADx can be a promising second reader in a clinical setting.
Fibered confocal spectroscopy and multicolor imaging system for in vivo fluorescence analysis (2007)

We report the design and implementation of spectroscopic and multicolor imaging capabilities into a fibered confocal fluorescence microscope (FCFM) already capable of in vivo imaging. The real time imaging device and the high resolution fiber probe make this system the first reported capable of performing multi color detection in the field of FCFM. The advantages of the system will allow in vivo morphological and functional imaging. Preliminary experiments were carried out in tissue samples to demonstrate the potential of the technique. The quality of the axial sectioning achieved in the confocal fluorescence spectroscopy mode is demonstrated experimentally, and applications to multicolor imaging are shown.
Detection of an Energy-Transfer Pathway in Cr-Photoredox Catalysis (2018)

We observe photocatalyst-based regioselectivity distinctions in Diels–Alder reactions using an electron-poor dienophile. We find that one complex, [Cr(Ph2phen)3](BF4)3, offers significantly higher selectivity than other Cr- and Ru-containing photosensitizers. Computational results, supported by excited-state quenching and reaction quantum yield studies, indicate that similar electron- and energy-transfer pathways are available to all photosensitizers studied, but [Cr(Ph2phen)3]3+ prefers an energy-transfer pathway that selectively orients the electron-poor alkene for cycloaddition, while an unselective outer-sphere radical-cation/electron-transfer pathway is favored for other photosensitizers.
Low‐dose CT image and projection dataset (2020)

This CT data library will facilitate the development and validation of new CT reconstruction and/or denoising algorithms, including those associated with machine learning or artificial intelligence. The provided clinical information allows evaluation of task-based diagnostic performance.
The Daily and the Everyday (2011)

Book Review| May 01 2011 The Daily and the Everyday RANDALL, BRYONY, Modernism, Daily Time and Everyday Life (Cambridge: Cambridge UP, 2008), pp. 232, cloth, $85.00. Mark Currie Mark Currie Search for other works by this author on: This Site Google Novel (2011) 44 (1): 115–120. https://doi.org/10.1215/00295132-1164437 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation Mark Currie; The Daily and the Everyday. Novel 1 May 2011; 44 (1): 115–120. doi: https://doi.org/10.1215/00295132-1164437 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsNovel Search Advanced Search The text of this article is only available as a PDF. © 2011 by Novel, Inc.2011Duke University Press Article PDF first page preview Close Modal You do not currently have access to this content.
Snapshot On-chip HDR ROIC Architectures (2015)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text C. Fernandez-Cull, H. Zhao, B. Shi, B. M. Tyrrell, J. Lin, and R. Raskar, "Snapshot On-chip HDR ROIC Architectures," in Imaging and Applied Optics 2015, OSA Technical Digest (online) (Optica Publishing Group, 2015), paper CM3E.3. Export Citation BibTex Endnote (RIS) HTML Plain Text Get Video Citation alert Save article
Multiphysics Simulation by Design for Electrical Machines, Power Electronics, and Drives (2017)

Presents applied theory and advanced simulation techniques for electric machines and drives This book combines the knowledge of experts from both academia and the software industry to present theories of multiphysics simulation by design for electrical machines, power electronics, and drives. The comprehensive design approach described within supports new applications required by technologies sustaining high drive efficiency. The highlighted framework considers the electric machine at the heart of the entire electric drive. The book also emphasizes the simulation by design concept—a concept that frames the entire highlighted design methodology, which is described and illustrated by various advanced simulation technologies. Multiphysics Simulation by Design for Electrical Machines, Power Electronics and Drives begins with the basics of electrical machine design and manufacturing tolerances. It also discusses fundamental aspects of the state of the art design process and includes examples from industrial practice. It explains FEM-based analysis techniques for electrical machine design—providing details on how it can be employed in ANSYS Maxwell software. In addition, the book covers advanced magnetic material modeling capabilities employed in numerical computation; thermal analysis; automated optimization for electric machines; and power electronics and drive systems. This valuable resource: Delivers the multi-physics know-how based on practical electric machine design methodologies Provides an extensive overview of electric machine design optimization and its integration with power electronics and drives Incorporates case studies from industrial practice and research and development projects Multiphysics Simulation by Design for Electrical Machines, Power Electronics and Drives is an incredibly helpful book for design engineers, application and system engineers, and technical professionals. It will also benefit graduate engineering students with a strong interest in electric machines and drives.
Static Induction Transistor Memory (1980)

Vertically configured dynamic SIT memory seems to exhibit high speed and low power operation with high packing density. Basic operations of SIT memory is demonstrated by using a single cell sample and a 36 bit cell array sample particularly on the measurements of the retention characteristic with temperature variations and the speed performance. In SIT memory, the voltage source is not supplied to the storage capacitor, so that there can exist two operational modes, i.e., majority carrier accumulation mode and the depletion mode. The depletion mode is found to be superior to the accumulation mode in the memory retention characteristics. These two modes of SIT memory operations are compared with the conventional dynamic MOS RAM operations.
Docking study and biological evaluation of pyrrolidine-based iminosugars as pharmacological chaperones for Gaucher disease (2015)

We report on the synthesis and biological evaluation of a series of α-1-C-alkylated 1,4-dideoxy-1,4-imino-d-arabinitol (DAB) derivatives as pharmacological chaperones for Gaucher disease. The parent compound, DAB, did not show inhibition of human β-glucocerebrosidase but showed moderate intestinal α-glucosidase inhibition; in contrast, extension of α-1-C-alkyl chain length gave a series of highly potent and selective inhibitors of the β-glucocerebrosidase. Our design of α-1-C-tridecyl-DAB (5j) produced a potent inhibitor of the β-glucocerebrosidase, with IC50 value of 0.77 μM. A molecular docking study revealed that the α-1-C-tridecyl group has a favorable interaction with the hydrophobic pocket and the sugar analogue part (DAB) interacted with essential hydrogen bonds formed to Asp127, Glu235 and Glu340. Furthermore, α-1-C-tridecyl-DAB (5j) displayed enhancement of activity at an effective concentration 10-times lower than isofagomine. α-1-C-Tridecyl-DAB therefore provides the first example of a pyrrolidine iminosugar as a new class of promising pharmacological chaperones with the potential for treatment of Gaucher disease.
Mapping human brain function with massively parallel high-speed three-dimensional photoacoustic computed tomography (2021)

Photoacoustic computed tomography (PACT) has been extensively explored in animal brains but never in the human brain due to its limited field of view (FOV), imaging speed, penetration depth, and sensitivity. Here, we present the first application of PACT in functional human brain imaging. Motor and language functional tasks were employed and performed by post-hemicraniectomy patients. The brain activities were recorded at a 10-cm–diameter FOV, 350-μm/2-s spatiotemporal resolution, and ~2-cm penetration depth using a newly developed massively parallel three-dimensional PACT system. Quantitative validation of the PACT results against 7 Tesla MRI revealed comparable angiographic structures and functional activation in the same FOV. The obtained results represent a critical step toward broader-scope human brain imaging applications using PACT technology.
User-Centric Virtual Sectorization for Millimeter-Wave Massive MIMO Downlink (2017)

The high training cost of the massive multiple-input multiple-output (MIMO) systems motivates the use of hybrid digital/analog (HDA) beamforming structures. This paper considers the joint design of analog beamformers when both link ends of a millimeter (mm)-wave massive MIMO system are equipped with such HDA structures. We aim to maximize the multi-user MIMO net average throughput of the downlink in a frequency division duplex system. To achieve this, we develop an optimization framework, namely, user-centric virtual sectorization (UCVS), to explore the tradeoff of training overhead, beamforming gain, and spatial multiplexing gain. In the UCVS, both the channel-statistics-based analog beamforming design and a non-orthogonal downlink training scheme are investigated to reduce the necessary cost of instantaneous channel acquisition. By maximizing an approximate net average throughput, we devise efficient algorithms to realize the suboptimal UCVS. With generic mm-wave channel models, we demonstrate by simulations that our proposed scheme outperforms the state-of-the-art methods in various typical scenarios of mm-wave communications.
CD4 and CD8 T cells from SIV-infecteg macaques have defective signaling responses after perturbation of either CD3 or CD2 receptors (1990)

Single-cell clones, designated E11S, C11R, and A1S, were obtained from the HuT-78 T cell line persistently infected with an isolate of Simian immunodeficiency virus (SIV), SIV/Mne. The infected clones, unlike uncloned uninfected HuT-78 cells, no longer expressed the CD4 marker and, after their CD3 receptors were cross-linked, had dramatically reduced intracellular free calcium ([Ca2+]i) responses. In one clone, E11S, the unresponsiveness was not limited to the inositol phospholipid pathway of signaling since a reduction in CD3-mediated activation of protein tyrosine kinase-dependent phosphorylation also was evident in this SIV-infected clone. These results led us to test whether T lymphocytes from animals infected with SIV had defective [Ca2+]i responses prior to detectable changes in CD4 levels or lymphadenopathy. The [Ca2+]i responses to both CD3 mAb and CD2 mAb were 10-50% less in T cells from Walter Reed stage 2 animals than in healthy controls. This anergy was more pronounced in chronically infected animals progressing to Walter Reed stage 3/4. The responses of these animals could not be augmented even when combinations of CD3 and CD4 mAb were used. Both CD4+CD44lo T cells, which are not infected with SIV, and the CD4+CD44hi T cell subset, previously shown to be the reservoir of SIV infection in blood, had pronounced defective responses to CD3 mAb. Similarly, both CD4+ and CD8+ T cells were consistently unresponsive in chronically infected animals, again implying that an indirect mechanism, rather than SIV infection per se, may be responsible for this immune dysfunction.
Influence of Particle Size and Polymer−Filler Coupling on Viscoelastic Glass Transition of Particle-Reinforced Polymers (2008)

The viscoelastic glass-to-rubber softening transition is analyzed for various cross-linked polymers reinforced with filler particles. We find that the loss modulus peak corresponding to the segmental relaxation process (glass transition) is not significantly affected by the particle surface area in carbon black-filled polybutadiene or by silane chemical coupling of poly(styrene-co-butadiene) to silica. Large differences in shape and magnitude of the peak in the loss tangent (tan δ) vs temperature are noted for these materials; however, this is due to variations in the storage modulus at small strains in the rubbery state, which is influenced by the nature of the jammed filler network. The use of a simple relaxation model demonstrates this feature of the viscoelastic glass transition in filled rubber. It is not necessary to invoke concepts involving a mobility-restricted polymer layer near the filler surfaces to explain the viscoelastic results. Atomic force microscopy conducted with an ultrasharp tungsten tip indicates that there may be some stiffening of the elastomer in the proximity of filler particles, but this does not translate into an appreciable effect on the segmental dynamics in these materials.
55. 123I-epidermal growth factor receptor monoclonal antibody (1992)

Virgolini, I.; Yang, Q.; Li, S. R.; Koller, E.; Valent, P.; Neuhold, N.; Angelberger, P.; Sinzinger, H. Author Information
Adenocarcinoma of the Prostate:Part II: Tissue Prognosticators (1993)

In this second review article of a two-part series on adenocarcinoma of the prostate, both established and experimental tissue prognosticators for adenocarcinoma of the prostate will be discussed. Consideration should be given to tissue indicators of prognosis for patients with prostatic carcinoma because this malignant neoplasm may exhibit remarkably variable biologic behavior. As in the first article, which addressed prostatic tissue sampling issues, the discussions will be centered on tissue specimen types. A final section focuses on experimental prognosticators for adenocarcinoma in prostatic tissues.
Power management of PHEV using quadratic programming (2011)

This paper studies the power management of a plug-in hybrid electric vehicle (PHEV) using quadratic programming. The proposed quadratic programming can obtain the global optimal solution of the power distribution between battery/motor and engine while maintaining vehicle performance. Computation time can be significantly saved compared with dynamic programming. Therefore, it can be used in real-time realisation. Two typical driving cycles, namely, UDDS and HWFET driving cycles are used to test the effectiveness of optimisation strategy. The simulation results indicate that significant amount of fuel can be saved with the proposed method.
Abstract 4682: Genomic profiles in gene expression and methylation help define the molecular characteristics of hairy cell leukemia subtypes (2017)

Abstract Hairy cell leukemia (HCL) until recently was characterized as a single blood and bone marrow malignancy, even though clinically at least two pathologies seemed to be at work. This study sought to confirm the clinical observations using genomic evidence. HCL is a chronic mature B-cell malignancy with distinctive immunophenotype, typically expressing CD20, CD22, CD25, CD11c, CD103, CD123, annexin A1 (ANXA1), and tartrate-resistant acid phosphatase (TRAP). Purine analog therapy is highly effective, with most patients achieving durable remissions. HCL- variant (HCLv) was first identified by Cawley et al. (1980) and recently recognized by the World Health Organization as a separate cancer. HCLv lacks CD25, ANXA1, TRAP, and BRAF V600E expression, and patients respond poorly to purine analogs. In order to find detailed biological information involving these two diseases, we studied the genome-wide gene expression and methylation profiles of 75 HCL patient samples; 67 were tested by both methods. Our study results indicate that HCL and HCLv show very distinct gene expression and methylation patterns. Many genes that are differentially expressed are involved in immunological and inflammatory response pathways. Several cancer associated genes such as ANXA1 and FLT3 are down-regulated in HCLv compared to HCL. Correlation patterns between methylation and gene expression for many genes such as ANXA1 suggest that methylation plays an import role in gene expression regulation for these malignancies. This study has begun the process of identifying better biomarkers for disease discrimination between HCL and HCLv and providing potential new targets for strongly needed therapies for HCLv. Citation Format: Daniel C. Edelman, Holly S. Stevenson, Yonghong Wang, Evgeny Arons, Joshua J. Waterfall, David Petersen, Hong Zhou, Paul S. Meltzer, Robert J. Kreitman. Genomic profiles in gene expression and methylation help define the molecular characteristics of hairy cell leukemia subtypes [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2017;77(13 Suppl):Abstract nr 4682. doi:10.1158/1538-7445.AM2017-4682
Patient Controlled Encryption: Patient Privacy in Electronic Medical Records (2009)

We explore the challenge of preserving patients’ privacy in electronic health record systems. We argue that security in such systems should be enforced via encryption as well as access control. Furthermore, we argue for approaches that enable patients to generate and store encryption keys, so that the patients’ privacy is protected should the host data center be compromised. The standard argument against such an approach is that encryption would interfere with the functionality of the system. However, we show that we can build an eﬃcient system that allows patients both to share partial access rights with others, and to perform searches over their records. We formalize the requirements of a Patient Controlled Encryption scheme, and give several instantiations, based on existing cryptographic primitives and protocols, each achieving a diﬀerent set of properties.