gebhart/patrepeval huggingface dataset:
Temporally coherent completion of dynamic video (2016)

We present an automatic video completion algorithm that synthesizes missing regions in videos in a temporally coherent fashion. Our algorithm can handle dynamic scenes captured using a moving camera. State-of-the-art approaches have difficulties handling such videos because viewpoint changes cause image-space motion vectors in the missing and known regions to be inconsistent. We address this problem by jointly estimating optical flow and color in the missing regions. Using pixel-wise forward/backward flow fields enables us to synthesize temporally coherent colors. We formulate the problem as a non-parametric patch-based optimization. We demonstrate our technique on numerous challenging videos.
ChemInform Abstract: Synthesis and Properties of Bis(2,5‐dimethylpyrrolo(3,4‐d)) tetrathiafulvalenes, a Class of Anellated Tetrathiafulvalene Derivatives with Excellent Electron Donor Properties. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Coronary Artery Fistula: Single‐Center Experience Spanning 17 Years (2007)

Origin of CAF was predominantly from the left system. Clinical presentations were variable depending on type, size of fistula, and the presence of other cardiac conditions. Management of CAF is still controversial and treatment of adult asymptomatic patients with nonsignificant shunting is still a matter of debate. Newer imaging modalities may enhance noninvasive diagnosis. A national registry is necessary for further insights into optimal treatment for large fistulae and the natural history of smaller fistulae.
Cytochrome aa3 electron-transfer reactions. Kinetics of hexaammineruthenium(II) reduction of the beef heart enzyme (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCytochrome aa3 electron-transfer reactions. Kinetics of hexaammineruthenium(II) reduction of the beef heart enzymeRobert A. Scott and Harry B. GrayCite this: J. Am. Chem. Soc. 1980, 102, 9, 3219–3224Publication Date (Print):April 1, 1980Publication History Published online1 May 2002Published inissue 1 April 1980https://pubs.acs.org/doi/10.1021/ja00529a054https://doi.org/10.1021/ja00529a054research-articleACS PublicationsRequest reuse permissionsArticle Views142Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Three-Dimensional Magnetohydrodynamic Equilibria of Toroidal Stellarators (1975)

Fully nonaxisymmetric magnetohydrodynamic equilibria have been calculated numerically for the Proto-Cleo stellarator utilizing a fully three-dimensional magnetohydrodynamic equilibrium code. It was found that recently observed anomalous circulating currents in stellarators may be a result of the equilibrium condition.
Fluorescence Probe with a pH-Sensitive Trigger (2006)

Acid-catalyzed hydrolysis was used as the mechanism to design a new type of environmentally sensitive fluorescence probe. A mild and selective periodate oxidation of the 2-amino alcohol of serine in the presence of a disulfide bond was developed to prepare dialdehyde peptides. Two identical fluorochrome hydrazide derivatives were then linked to the dialdehyde peptide forming an acid-labile hydrazone linkage. This self-quenched probe is weakly fluorescent at a physiological pH of 7.4 but shows more than 3-fold fluorescence enhancement at pH 4.5.
Roll-Over Prevention System for Commercial Vehicles ? Additional Sensorless Function of the Electronic Brake System (1999)

Recent experiences have shown that even small-medium size passenger cars face an accident which has been connected with commercial vehicles so far: the roll-over. The roll-over is the most horrible accident type for truck drivers, since he/she does not have any indication before it happens, and consequently does not react properly. This article discusses some of the problems of the commercial vehicle stability in general, and offers a solution for detecting and avoiding roll-over by using the existing sensors and actuators of electronic brake system (EBS).
Use of Intertransmission Coherence for Haze Artifact Suppression in Cardiovascular Synthetic Aperture Ultrasound Imaging (2021)

Synthetic aperture (SA) beamforming is a principal technology of modern medical ultrasound imaging. In that the use of focused transmission provides superior signal-to-noise ratio (SNR) and is promising for cardiovascular diagnosis at the maximum imaging depth of about 160 mm. But there is a pitfall in increasing the frame rate to more than 80 frames per second (frames/s) without image degradation by the haze artifact produced when the transmit foci (SA virtual sources) placed within the imaging field. We hypothesize that the source of this artifact is a grating lobe caused by coarse (decimated) multiple transmission and manifesting in the low brightness region in the accelerated-frame-rate images. We propose an intertransmission coherence factor (ITCF) method suppressing haze artifacts caused by coarse-pitch multiple transmission. The method is expected to suppress the image blurring because the SA grating lobe signal is less coherent than the main lobe signals. We evaluated an ITCF algorithm for suppressing the grating artifact when the transmission pitch is up to four times larger than the normal pitch (equivalent to 160 frames/s). In in-vitro and in-vivo experiments, we demonstrated the strong relation of haze artifact with the grating lobe due to the coarse-pitch transmission. Then, we confirmed that the ITCF method suppresses the haze artifact of a human heart by 15 dB while preserving the spatial resolution. The ITCF method combined with focused transmission SA beamforming is a valid method for getting cardiovascular ultrasound B-mode images without making a compromise in the trade-off relationship between the frame rate and the SNR.
A Mini-FAB simulation model comparing FIFO and MIVP(R) schedule policies (outer loop), and PID and H/sup ∞/ machine controllers (inner loop) for semiconductor diffusion bay maintenance (2002)

This Multiscale Integration of Manufacturing and Assembly Processes (MIMAP) demonstration project investigates the integration of two or more Thrust Area Groups (TAGs) by creating a flow of information and processes from two areas of research. The control theory research of two different controllers for diffusion furnaces used in semiconductor manufacturing which predict a specific window of machine failure, the mean-time-before-failure (MTBF). The objective is to increase yield, decrease cycle time, work-in-progress (WIP) and production costs. A global factory Minimum Inventory Variability Scheduling policy (MIVP(R)), used to decrease cycle time and cycle time variance when compared to a first-in-first-out (FIFO) scheduling policy, was used to make the comparisons between the two inner and outer loop controllers. The project's Cross Cutting Methodologies (CCMs) is ensured by the participation of faculty from three different colleges (LAS, CEAS, and CTAS) and two electrical engineering doctoral students.
A 17-Gene Genomic Prostate Score Assay Provides Independent Information on Adverse Pathology in the Setting of Combined Multiparametric Magnetic Resonance Imaging Fusion Targeted and Systematic Prostate Biopsy (2018)

The prostate score assay result is an independent predictor of adverse pathology findings in patients who were diagnosed with very low, low or intermediate risk prostate cancer in the setting of multiparametric magnetic resonance imaging fusion prostate biopsy. This assay can be useful as an independent technology or an adjunct technology to multiparametric magnetic resonance imaging to individualize risk stratification of low and intermediate risk prostate cancer.
Development and research on new anode with three-dimensionally ordered structure for lithium ion battery (2011)

Highly patterned cylindrical Sn–Ni alloy with three-dimensionally ordered macroporous (3DOM) structure was successfully prepared by colloidal crystal templating method combined with electroplating process using photoresist substrate. The alloy revealed stable cyclability, and no capacity fade was observed until the two hundredth cycle at a state of charge of 67%. It is concluded that the highly patterned cylindrical Ni–Sn alloy with 3DOM structure is a promising structure.
The cancer testis antigens CABYR-a/b and CABYR-c are expressed in a subset of colorectal cancers and hold promise as targets for specific immunotherapy (2021)

CABYR a/b and c hold promise as specific immunotherapy targets, however, a larger and more diverse group of tumors (Stage 1-4) needs to be assessed and evaluation of blood for anti-CABYR antibodies is needed to pursue this concept.
Breath of relief: apparent pulmonary nodule due to heterotopic ossification (2018)

Extrapulmonary heterotopic ossification appears similarly to pulmonary nodules on CXR, and is in the differential for pulmonary nodules. It occurs following the bone trauma, and in early stages appears similarly to tumors. Heterotopic ossification is diagnosed by its calcification pattern via MRI or ultrasound and managed conservatively unless symptoms develop.
Wetting Behavior of Elastomer-Modified Glass Fibers (2001)

Interfacial properties of glass fibers coated by admicellar polymerization with a styrene−isoprene copolymer thin film have been investigated. Advancing and receding contact angles on single glass fibers as small as 6.2 μm in diameter were measured at slow meniscus velocities (2.0 μm/s) by using the Wilhelmy method with probe liquids of various hydrophobic/hydrophilic characteristics. Distinctly different contact angles were obtained from the dynamic wetting of fibers with different surface treatments. In water, the average advancing contact angle for admicellar-modified fibers was high (θadv ≈ 65−75°), suggesting an increased hydrophobicity as compared to that of the fully wettable desized fibers. Furthermore, it was found that both fibers with silane coupling agents and admicellar-coated fibers are chemically heterogeneous on their surfaces. Contact line pinning behavior induced by regions of different surface energy, as well as high hysteresis values, indicates that the ultrathin styrene−isoprene film is not uniform throughout the glass on a macroscopic length scale. However, when assessed with an epoxy resin (e.g. EPON 815C), the admicellar polymerization treatment produced fibers with statistically identical wetting characteristics to those of fibers containing a proprietary sizing. Good adhesional wetting of the elastomer-modified fibers by an epoxy resin may be indicative of an adequate interaction between fiber and matrix in large-scale composite fabrication.
Comprehensive physical and electrical characterizations of NO nitrided SiO 2 /4H-SiC(1120) interfaces (2022)

Abstract Nitridation of SiO 2 /4H-SiC(112̄0) interfaces with post-oxidation annealing in an NO ambient (NO-POA) and its impact on the electrical properties were investigated. Sub-nm-resolution nitrogen depth profiling at the interfaces was conducted by using a scanning X-ray photoelectron spectroscopy microprobe. The results showed that nitrogen atoms were incorporated just at the interface and that interface nitridation proceeded much faster than at SiO 2 /SiC(0001) interfaces, resulting in a 2.3 times higher nitrogen concentration. Electrical characterizations of metal-oxide-semiconductor capacitors were conducted through capacitance–voltage ( C – V ) measurements in the dark and under illumination with ultraviolet light to evaluate the interface defects near the conduction and valence band edges and those causing hysteresis and shifting of the C – V curves. While all of these defects were passivated with the progress of the interface nitridation, excessive nitridation resulted in degradation of the MOS capacitors. The optimal conditions for NO-POA are discussed on the basis of these experimental findings.
IL-2 Upregulates CD86 Expression on Human CD4+ and CD8+ T Cells (2012)

The glycoprotein CD86 is an important costimulatory molecule that has been shown to be predominantly expressed on APCs, such as dendritic cells, macrophages, and B cells. More recently, CD86 was also detected on T cells in specific pathological conditions. The mechanisms of how CD86 might be induced and its functional role in T cells are not well understood. In the present study, we showed that treatment with IL-2 markedly upregulated CD86, but not CD80, in human CD4(+) and CD8(+) T cells. This upregulation occurred in the absence of bystander cells, and isolated naive CD4(+) or CD8(+) T cells exhibited different time-dependent CD86-expression patterns in response to IL-2. Upregulation of CD86 on activated T cells was reduced by Abs that block IL-2 and IL-2Rα (CD25), indicating a receptor-mediated mechanism. IL-2-dependent CD86 upregulation was blocked by pharmacological inhibitors of the NFAT and mammalian target of rapamycin pathways and was largely reduced by simultaneous exposure to IFN-α. Importantly, a marked increase in CD86 on T cells was also observed in vivo in IL-2-treated patients. In conclusion, IL-2 upregulates CD86 expression on human CD4(+) and CD8(+) T cells via a receptor-dependent mechanism that involves the NFAT and mammalian target of rapamycin pathways.
Prediction of Whole-Cell Transcriptional Response with Machine Learning (2021)

Abstract Applications in synthetic and systems biology can benefit from measuring whole-cell response to biochemical perturbations. Execution of experiments to cover all possible combinations of perturbations is infeasible. In this paper, we present the host response model (HRM), a machine learning approach that takes the cell response to single perturbations as the input and predicts the whole cell transcriptional response to the combination of inducers. We find that the HRM is able to qualitatively predict the directionality of dysregulation to a combination of inducers with an accuracy of &gt;90% using data from single inducers. We further find that the use of known prior, known cell regulatory networks doubles the predictive performance of the HRM (an R 2 from 0.3 to 0.65). This tool will significantly reduce the number of high-throughput sequencing experiments that need to be run to characterize the transcriptional impact of the combination of perturbations on the host.
"Wireless Paint": Code Design for 3D Orientation Estimation with Backscatter Arrays (2020)

In this paper, we consider the problem of estimating the orientation of an object that has been custom-"painted" by an array of backscatter tags. We pose the problem as a coding matrix design with the objective of minimizing orientation estimation error. We show that it is only necessary to consider a subset of code configurations and provide a tractable linear program to find the optimal coding strategy. We provide simulation results using an icosahedral tag arrangement.
Echocardiographic AV-interval optimization in patients with reduced left ventricular function (2004)

Ritter's method is also effective for optimization of AV intervals among patients with reduced left ventricular function (EF < 35%). The results obtained by RNV correlate well with those from Ritter's method. Individual programming of the AV interval is fundamentally essential in all cases.
InGaAs/InP single-photon avalanche diodes show low dark counts and require moderate cooling (2008)

InGaAs/InP devices suitable as Single-Photon Avalanche Diodes (SPADs) for photon counting and photon timing applications in the near-infrared provide good detection efficiency and low time jitter, together with fairly low darkcount rate at moderately low temperatures. However, their performance is still severely limited by the afterpulsing effect, caused by carriers trapped into deep levels during the avalanche current flow and later released. We present preliminary experimental characterization of recently-developed InGaAs/InP detectors that can promisingly be operated slightly cooled. We investigate the primary dark-count rate, taking into account both thermal generation in the InGaAs absorption layer and trap-assisted tunnelling in the InP multiplication layer. We report on improvements obtainable by selecting the proper operating conditions and electronic circuit solutions. The fundamental role played by the front-end circuits in minimizing the effects of afterpulsing is assessed and demonstrated. We report the performance of a 25 &mu;m-diameter InGaAs/InP SPAD at 1550 nm wavelength, with dark count rate of 400 cps (count per seconds) at 175 K and just 2000 cps at 225 K, with afterpulsing showing off only below T<sub>OFF</sub>=10&mu;s. The photon timing resolution is 100 ps (FWHM, Full Width at Half Maximum) at 7 V of excess bias.
Metronomic scheduling of imatinib abrogates clonogenicity of neuroblastoma cells and enhances their susceptibility to selected chemotherapeutic drugs in vitro and in vivo (2008)

Imatinib is currently in early clinical trials as targeted therapy for relapsed neuroblastomas and other childhood solid tumors expressing platelet-derived growth factor receptors (PDGFR) or c-Kit. Short-term treatment with imatinib in clinically achievable concentrations is ineffective in neuroblastoma in vitro. However, clinically, imatinib is administered daily over long time periods. The effects of combining imatinib with chemotherapy in neuroblastoma are unknown. Here, a panel of neuroblastoma cell lines (n = 5) were studied, representing tumors with different biological (MYCN-amplification +/-) and clinical (drug resistance) features. Using a protracted low-dose treatment schedule (1-3 weeks; 0.5-5microM) imatinib dose-dependently inhibited proliferation and clonogenic survival for all tested cell lines with IC50 <2.5microM. In contrast, short-term treatment (<96 hrs) was ineffective. Low-dose imatinib was synergistic in combination with doxorubicin and caused increased G2/M- and S-phase arrest and apoptosis as evidenced by enhanced caspase-3 activation and sub-G1 DNA accumulation. A significant but less pronounced effect was observed when imatinib was combined with etoposide or vincristine, as opposed to cisplatin, melphalan, or irinotecan. All cell lines expressed PDGFRbeta, whereas no protein expression of PDGFRalpha was detected in MYCN amplified cell lines. PDGF-BB caused PDGFRbeta phosphorylation and partially rescued neuroblastoma cells from doxorubicin-induced apoptosis, in an imatinib-sensitive manner. In vivo, treatment with imatinib in combination with doxorubicin induced a significant growth inhibition of established neuroblastoma xenografts. These findings suggest clinical testing of imatinib in combination with selected chemotherapeutic drugs, in particular doxorubicin, in children with high-risk neuroblastoma.
ChemInform Abstract: REDUCTIVE DEAMINATION OF ARYLAMINES BY ALKYL NITRITES IN N,N‐DIMETHYLFORMAMIDE. A DIRECT CONVERSION OF ARYLAMINES TO AROMATIC HYDROCARBONS (1978)

Abstract Arylamine (I) werden durch Behandlung mit Alkylnitriten (II) zu (III) desaminiert.
Abstract CT060: ACTION: A randomized phase 3 study of dordaviprone (ONC201) in patients with newly diagnosed H3 K27M-mutant diffuse glioma (2023)

Abstract Background: H3 K27M-mutant diffuse midline glioma is a universally fatal malignancy primarily affecting children and young adults. While radiotherapy (RT) provides transient benefit, no effective systemic therapy is currently available and current standard of care is RT followed by monitoring. Dordaviprone (ONC201), a first-in-class imipridone, is an oral, blood-brain barrier penetrating, selective small molecule antagonist of dopamine receptor D2/3 (DRD2) and agonist of the mitochondrial protease ClpP. An integrated pooled analysis of five open-label trials previously demonstrated efficacy in dordaviprone-treated patients with recurrent disease. This phase 3 trial will be the first randomized, controlled study evaluating dordaviprone in patients with H3 K27M-mutant disease. Methods: ACTION (NCT05580562) is a randomized, double-blind, placebo-controlled, parallel-group, international Phase 3 study of dordaviprone in patients with newly diagnosed H3 K27M-mutant diffuse glioma. Patients who have completed standard frontline radiotherapy will be randomized 1:1:1 to receive placebo, once-weekly dordaviprone, or twice-weekly dordaviprone on two consecutive days. Primary efficacy endpoints are overall survival (OS) and progression-free survival (PFS) in all participants; PFS will be assessed by response assessment in neuro-oncology-high grade glioma by blind independent central review. Other objectives include assessments of safety, additional efficacy endpoints, clinical benefit, quality of life, pharmacokinetics, biomarkers, and healthcare resource utilization. Eligible patients will have histologically confirmed H3 K27M-mutant diffuse glioma, a Karnofsky/Lansky performance status ≥70, and completed first-line radiotherapy. Eligibility will not be restricted based on age; however, patients must be ≥10 kg at time of randomization. Patients with a primary spinal tumor, diffuse intrinsic pontine glioma, leptomeningeal disease, or cerebrospinal fluid dissemination are not eligible. ACTION is currently enrolling in the United States, with additional sites to be open internationally in 2023. Citation Format: Isabel Arrillaga-Romany, Andrew Lassman, Susan L. McGovern, Sabine Mueller, Louis B. Nabors, Martin van den Bent, Michael Vogelbaum, Joshua E. Allen, Allen S. Melemed, Rohinton S. Tarapore, Dewen Yang, Patrick Wen, Timothy Cloughsey. ACTION: A randomized phase 3 study of dordaviprone (ONC201) in patients with newly diagnosed H3 K27M-mutant diffuse glioma [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 2 (Clinical Trials and Late-Breaking Research); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(8_Suppl):Abstract nr CT060.