gebhart/patrepeval huggingface dataset:
CSI Reference Signal Multiplexing Using Carrier Frequency Swapping for FDD High-Order MIMO SDM (2014)

This paper proposes channel state information - reference signal (CSI-RS) multiplexing employing carrier frequency swapping for frequency division duplex (FDD) high-order multiple-input multiple-output (MIMO) spatial division multiplexing (SDM). In the proposed CSI-RS multiplexing method, the carrier frequency of a fast Fourier transform (FFT) block for multiplexing time division duplex (TDD) CSI-RSs within a subframe is swapped between the downlink and uplink. By using the proposed TDD CSI-RS multiplexing method, the CSI for performing precoding and link adaptation is estimated in the reverse link by taking advantage of the channel reciprocity feature. By using the proposed TDD CSI-RS multiplexing method, the RS overhead is decreased according to the increase in the number of simultaneously accessing sets of user equipment for multiuser MIMO. Moreover, the proposed TDD CSI-RS multiplexing method does not need fast feedback signals that track instantaneous channel response including the channel quality indicator (CQI), rank indicator (RI), and precoding matrix indicator (PMI) except for the slow feedback of the average interference level from the surrounding cells.
Supplementary Methods from Lrig1 Is an Estrogen-Regulated Growth Suppressor and Correlates with Longer Relapse-Free Survival in ERα-Positive Breast Cancer (2023)

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CE-MALDI-MS/MS for Proteomic Profiling and Multiplexed Quantification of Human Cerebrospinal Fluid (CSF) (2007)

CE-MALDI-MS/MS for Proteomic Profiling and Multiplexed Quantification of Human Cerebrospinal Fluid (CSF)
Evaluation of a Ventricular Assist Device System (2012)

Inadequate research exists regarding testing of a ventricular assist device (VAD) for susceptibility to radiation damage. Specifically, minimal data are available to radiation oncologists prescribing treatment plans for patients with an implanted VAD. As the number of implanted devices increases, patients requiring radiation at tissue sites near or at the device will increase. The purpose of this study is to provide the first analysis of radiation effects of proton beams on VADs. Five left VAD (LVAD) pumps (HeartWare Inc., Miami Lakes, FL) were exposed to proton beam radiation at a calibrated dose rate of 5 Gy/min up to a cumulative dose of 70 Gy. The Heartware LVAD pump recorded parameters including power (W), speed (revolutions/min), and estimated flow (L/min). Analysis of collected data after each irradiation found no deviation in pump parameters from baseline values. The Heartware LVAD pump exhibited no change in device function when directly irradiated by a high energy proton beam. Secondary neutron fluence created in the proton beam during irradiation had no effect on external components including the system controller and batteries powering the Heartware LVAD.
Analyzing path delays for accelerated testing of logic chips (2015)

We develop a test methodology utilizing the critical path delay to monitor and predict the degradation of circuits during a ramp voltage stress (RVS). Stress is applied by looping functional patterns during RVS. Our results demonstrate that the degradation behavior of a functional circuit can be characterized and analyzed with RVS in a manner similar to that developed for a single transistor. This alternative fast test lends itself to in-line testing with reduced times and small sample numbers.
Second-harmonic generation on the nanoscale: new routes for surface and bulk investigations (2005)

Second-harmonic generation from individual nanostructures is demonstrated. New symmetry selection rules derived for asymmetric nanoparticles allow for the distinction of different nonlinear source polarizations and enable simultaneous surface and bulk investigations.
Nickel-Base Alloys for Heat Exchangers (2006)

Abstract High temperature heat exchangers require the use of oxidation and creep-resistant alloys. Austenitic stainless steels are often specified for reasons of cost, availability, and ease of fabrication. Water vapor, present in the exhaust gas as a by-product of combustion, has been shown to be detrimental to the elevated temperature oxidation resistance of common stainless steels. Increasing the amount of chromium and nickel in heat-resistant alloys appears to alleviate the risk of breakaway oxidation in air containing water vapor. This paper gives results and analysis from extended high-temperature oxidation testing in air with and without added levels of water vapor of two common wrought nickel-base superalloys (UNS N06626 and UNS N06002) and an experimental austenitic stainless steel (Fe-20Cr-25Ni+Nb). The alloys were tested as thin foils, as the primary focus of this study was materials for primary surface recuperator-type heat exchangers. Alloy 625 exhibited significant weight losses due to oxide scale evaporation in humidified air. The other two alloys in the test program were resistant to this form of attack due to the formation of an external manganese chromate spinel oxide scale layer. Both nickel-base alloys proved resistant to breakaway oxidation, but the stainless steel exhibited mixed oxide nodule formation during the most severe exposures. Conclusions relevant to the use of such materials in water vapor-bearing environments are provided.
Grating assisted rectangular integrated optical microresonators (2003)

A wide, multimode segment of a dielectric optical waveguide, enclosed by Bragg reflectors and evanes-cently coupled to adjacent port waveguides, can constitute the cavity in an integrated optical microresonator. We outline a design strategy for these devices and give results of numerical simulations by means of mode expansion techniques, that exemplify the specific spectral response of the standing wave resonators.
A genetic algorithm approach to detecting temporal patterns indicative of financial statement fraud (2007)

Abstract This study presents a genetic algorithm approach to detecting financial statement fraud. The study uses a sample comprising a target class of 51 companies accused by the Securities and Exchange Commission of improperly recognizing revenue and a peer class of 339 companies matched on industry and size (revenue). Variables include 76 comparative metrics, based on specific financial metrics and ratios that capture company performance in the context of historical and industry performance, and nine company characteristics. Time‐based patterns detected by the genetic algorithm accurately classify 63% of the target class companies and 95% of the peer class companies. Copyright © 2007 John Wiley &amp; Sons, Ltd.
Long-Term Outcome Following Radical Prostatectomy in Men With Clinical Stage T3 Prostate Cancer (2006)

More than half (52%) of our patients remained free of disease recurrence following radical prostatectomy. In our series neoadjuvant hormonal therapy offered no advantage with respect to disease recurrence. Radical prostatectomy remains an integral component in the treatment of select patients with clinical stage T3 prostate cancer.
A Role for Data Science in Precision Nutrition and Early Brain Development (2022)

Multimodal brain magnetic resonance imaging (MRI) can provide biomarkers of early influences on neurodevelopment such as nutrition, environmental and genetic factors. As the exposure to early influences can be separated from neurodevelopmental outcomes by many months or years, MRI markers can serve as an important intermediate outcome in multivariate analyses of neurodevelopmental determinants. Key to the success of such work are recent advances in data science as well as the growth of relevant data resources. Multimodal MRI assessment of neurodevelopment can be supplemented with other biomarkers of neurodevelopment such as electroencephalograms, magnetoencephalogram, and non-imaging biomarkers. This review focuses on how maternal nutrition impacts infant brain development, with three purposes: (1) to summarize the current knowledge about how nutrition in stages of pregnancy and breastfeeding impact infant brain development; (2) to discuss multimodal MRI and other measures of early neurodevelopment; and (3) to discuss potential opportunities for data science and artificial intelligence to advance precision nutrition. We hope this review can facilitate the collaborative march toward precision nutrition during pregnancy and the first year of life.
Enhanced Two-Photon Absorption in Polycrystalline Silicon (2011)

We discuss measurements of the two-photon absorption coefficient (β) in polycrystalline silicon deposited in a scaled CMOS process; measurements in thin film, waveguides and microring resonators indicate β is over two orders of magnitude larger than in crystalline silicon.
Large diameter high-speed InGaAs receivers for free-space lasercom (2007)

The U. S. Naval Research Laboratory (NRL) and OptoGration, Inc. have collaborated in the development and testing of large area, high speed InGaAs avalanche photodiode (APD) receivers for use in free-space lasercom systems. A 200 micron diameter InGaAs APD receiver has been tested in a free-space lasercom testbed and has demonstrated sensitivities of -42.4 dBm at 622 Mbps and -44.8 dBm at 155 Mbps. A 100 micron diameter receiver has been tested with a resulting sensitivity of -35.75 dBm at 2.4883 Gbps. These receivers are made possible due to OptoGration's capability to manufacture a large area, high speed InGaAs APD with an effective ionization ratio of < 0.2 and by matching the APD device with an appropriate transimpedance amplifier and limiting amplifier. Development and testing of the APD receivers will be described below.
70.46 Tb/s Over 7,600 km and 71.65 Tb/s Over 6,970 km Transmission in C+L Band Using Coded Modulation With Hybrid Constellation Shaping and Nonlinearity Compensation (2017)

We demonstrate 70.46 Tb/s transmission over 7,600 km and 71.65 Tb/s transmission over 6,970 km with C+L band EDFAs using a multidimensional coded modulation format with hybrid probabilistic and geometric constellation shaping. The proposed format (4D-PS-9/12-56APSK) is designed to approach Shannon limit and to improve the performance of nonlinearity compensation over conventional and probabilistically shaped 2-D formats. The receiver DSP uses multistage nonlinearity compensation that includes fast least-mean-square equalizer and generalized filter in addition to digital back propagation. The adaptive linear filters are aided by coded modulation decisions. We study the contribution of each algorithm and show an average total nonlinearity compensation benefit of 1.4 dBQ at the designed amplifier power.
The Structure of Apolipoprotein A-II in Discoidal High Density Lipoproteins (2007)

It is well accepted that high levels of high density lipoproteins (HDL) reduce the risk of atherosclerosis in humans. Apolipoprotein A-I (apoA-I) and apoA-II are the first and second most common protein constituents of HDL. Unlike apoA-I, detailed structural models for apoA-II in HDL are not available. Here, we present a structural model of apoA-II in reconstituted HDL (rHDL) based on two well established experimental approaches: chemical cross-linking/mass spectrometry (MS) and internal reflection infrared spectroscopy. Homogeneous apoA-II rHDL were reacted with a cross-linking agent to link proximal lysine residues. Upon tryptic digestion, cross-linked peptides were identified by electrospray mass spectrometry. 14 cross-links were identified and confirmed by tandem mass spectrometry (MS/MS). Infrared spectroscopy indicated a beltlike molecular arrangement for apoA-II in which the protein helices wrap around the lipid bilayer rHDL disc. The cross-links were then evaluated on three potential belt arrangements. The data clearly refute a parallel model but support two antiparallel models, especially a "double hairpin" form. These models form the basis for understanding apoA-II structure in more complex HDL particles.
Joint Positioning and Tracking via NR Sidelink in 5G-Empowered Industrial IoT: Releasing the Potential of V2X Technology (2021)

The fifth generation (5G) mobile networks with enhanced connectivity and positioning capabilities play an increasingly important role in the development of automated vehicle-to-everything (V2X) and other advanced industrial Internet of Things (IoT) systems. In this article, we address the prospects of 5G New Radio (NR) sidelink based V2X networks and their applicability for increasing the situational awareness, in terms of continuous tracking of moving connected machines and vehicles, in industrial systems. For increased system flexibility and fast deployments, we assume that the locations of the so-called anchor nodes are unknown, and describe an extended Kalman filter-based joint positioning and tracking framework in which the locations of both the anchor nodes and the target nodes can be estimated simultaneously. We assess and demonstrate the achievable 3D positioning and tracking performance in the context of a realistic industrial warehouse facility, through extensive ray-tracing based evaluations at the 26 GHz NR band. Our findings show that when both angle-based and time-based measurements are utilized, reaching sub-1 meter accuracy is realistic and that the system is also relatively robust against different node geometries. Finally, several research challenges towards achieving robust, high-performance and cost-efficient positioning solutions are outlined and discussed, identifying various potential directions for future work.
Toward real-time clamping load measurement using DSPI (2012)

Finding a reliable technique to determine clamping load in bolted joint has been a challenging problem for several years. A new technique that was recently introduced, addresses this problem by deploying the Digital Speckle Pattern Interferometry (DSPI) technique to measure the deformation of the surface being clamped and correlate it to the clamping load. The optical part of the system has been developed using the Spatial Phase Shifting technique to determine the deformation caused by the applied torque. The images produced by this technique are of low signal-to-noise ratio and require filtering in order to achieve accurate deformation calculation. However, image filtering requires significant processing time, particularly in video streams, which can cause delays in the system and therefore undesirable results. In this paper we propose a method to automate the process of calculating the deformation in a suitable time frame. This method uses a new filtering technique to reduce the computation overhead of the controlling software and therefore increase the overall speed of the system by up to seven times. Achieving a practical processing time in the software will result in more robust and reliable control over the fastener and therefore higher accuracy of clamping load. The methods used to design this system ultimately can automate the entire process of clamping and provide a reliable closed-loop clamping load controller for bolted joint.
Imidazo[4,5-b]Pyridines: From Kinase Inhibitors to more DiversifiedBiological Properties (2023)

Imidazo[4,5-b</i>]pyridines are amongst the oldest known heteroaromatic derivatives. Their structural similarity with purine basis has however aroused the curiosity of biologists and resulted in the developments of innovative bioactive compounds. This review thus firstly describes the main synthetic ways currently used to produce imidazo[ 4,5-b</i>]pyridine derivatives, and secondly gives examples of their potential, especially focusing on protein inhibition abilities, thus opening the way to applications as anti-cancer or antimicrobial agents.
Visible-Light-Activated Enantioselective Perfluoroalkylation with a Chiral Iridium Photoredox Catalyst (2015)

A visible-light-activated enantioselective radical perfluoroalkylation of 2-acyl imidazoles with perfluoroalkyl iodides (CF<sub>3</sub>I, C<sub>3</sub>F<sub>7</sub>I, C<sub>4</sub>F<sub>9</sub>I, C<sub>6</sub>F<sub>13</sub>I, C<sub>8</sub>F<sub>17</sub>I and C<sub>10</sub>F<sub>21</sub>I) and perfluorobenzyl iodide at the α-position of the carbonyl group is reported. Enantioselectivities with up to >99.5% ee are achieved. The process uses a dual-function chiral Lewis acid/photoredox catalyst at loadings of 2–4 mol% and constitutes a redox-neutral, electron-catalyzed reaction that proceeds via intermediate perfluoroalkyl radicals.
Transmission characteristics of crossing slot-waveguides with finite core-height (2012)

We investigate transmission characteristics of two types of crossing slot-waveguides using three-dimensional finite element method, a direct crossing and a crossing with filled slots. Results show that three-dimensional analysis considering the finite core-height is indispensable.
Edge-Aware Network for Kidneys and Kidney Tumor Semantic Segmentation (2019)

Automated segmentation of kidneys and kidney tumors is an important step in quantifying the tumor’s morphometrical details to monitor the progression of the disease and accurately compare decisions regarding the kidney tumor treatment. Manual delineation techniques are often tedious, error-prone and require expert knowledge for creating unambiguous representation of kidneys and kidney tumors segmentation. In this work, we propose an end-to-end boundary aware fully Convolutional Neural Networks (CNNs) for reliable kidney and kidney tumor semantic segmentation from arterial phase abdominal 3D CT scans. We propose a segmentation network entailing an encoder-decoder that specifically accounts for organ/tumor edge information by devising a dedicated network edge branch and edge-aware loss terms. We have evaluated our model on 2019 MICCAI KiTS Kidney Tumor Segmentation challenge dataset. Based on our own data split, we achieved 0.970 dice for kidney &amp; tumor, and 0.834 dice for tumor segmentation.
Facial expression recognition with FHOG features (2018)

Facial expression recognition is a popular computer vision subject that has many applications such as human-computer interaction and behavior analysis. As for many computer vision problems, lighting and contrast differences increase the difficulty of the problem. Especially the non-planar structure of the face, protruding regions such as the nose and chin and recessed regions such as eye sockets cause variations in lighting. Another problem with facial expression recognition problems is that the multi-scale detection methods do not align the faces accurately. This leads to comparing features that are extracted from different facial regions, which degrades performance. FHOG features are a contrast-sensitive variation of histogram oriented gradients (HOG) features, which perform well at object detection applications. In this study, the performance of FHOG features at facial expression recognition is investigated. Additionally, aligning with respect to the facial landmarks is proposed to prevent performance degradation due to misalignment. The proposed method is shown to deliver 93% accuracy in facial expression recognition in the extended Cohn-Kanade dataset.
PARP14 is a novel target in STAT6 mutant follicular lymphoma (2022)

The variable clinical course of follicular lymphoma (FL) is determined by the molecular heterogeneity of tumor cells and complex interactions within the tumor microenvironment (TME). IL-4 producing follicular helper T cells (T<sub>FH</sub>) are critical components of the FL TME. Binding of IL-4 to IL-4R on FL cells activates JAK/STAT signaling. We identified STAT6 mutations (STAT6<sup>MUT</sup>) in 13% of FL (N = 33/258), all clustered within the DNA binding domain. Gene expression data and immunohistochemistry showed upregulation of IL-4/STAT6 target genes in STAT6<sup>MUT</sup> FL, including CCL17, CCL22, and FCER2 (CD23). Functionally, STAT6<sup>MUT</sup> was gain-of-function by serial replating phenotype in pre-B CFU assays. Expression of STAT6<sup>MUT</sup> enhanced IL-4 induced FCER2/CD23, CCL17 and CCL22 expression and was associated with nuclear accumulation of pSTAT6. RNA sequencing identified PARP14 -a transcriptional switch and co-activator of STAT6- among the top differentially upregulated genes in IL-4 stimulated STAT6<sup>MUT</sup> lymphoma cells and in STAT6<sup>MUT</sup> primary FL cells. Quantitative chromatin immunoprecipitation (qChIP) demonstrated binding of STAT6<sup>MUT</sup> but not STAT6<sup>WT</sup> to the PARP14 promotor. Reporter assays showed increased IL-4 induced transactivation activity of STAT6<sup>MUT</sup> at the PARP14 promotor, suggesting a self-reinforcing regulatory circuit. Knock-down of PARP14 or PARP-inhibition abrogated the STAT6<sup>MUT</sup> gain-of-function phenotype. Thus, our results identify PARP14 as a novel therapeutic target in STAT6<sup>MUT</sup> FL.
Catalytic Enantioselective Synthesis of (20S)-Camptothecin Intermediates Using Cyanosilylation of Ketones Promoted by D-Glucose-derived Lanthanide Catalyst (2003)

An efficient catalytic enantioselective synthetic route was developed for Curran's versatile camptothecin intermediate (5).The key step is the catalytic enantioselective cyanosilylation of ketone (7) using a chiral samarium (Sm) complex.The target ketone cyanohydrin (6) was obtained with 90% ee using 2 mol % of the catalyst.A gadolinium (Gd) complex derived from the same chiral ligand could also be used as an enantioselective catalyst to synthesize Corey's intermediate (11).
Anion Exchange Perovskite Quantum-Dots for Highly Efficient Light-Emitting-Devices (2019)

All inorganic cesium lead halide perovskite with CsPbX <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> (X = Cl - , Br <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-</sup> , or I <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-</sup> ) have been demonstrated a novel classified colloidal quantum dots (QDs). Perovskite QDs have also expected great potential for the application in light-emitting devices (LEDs) due to their superior chemical stability, narrow emission spectra enable coverage the next generation of standard for display, B.T. 2020 color gamut, high photoluminescence quantum yields (PLQYs) of up to 90%, plainly tunable emission wavelength in full visible range by halide anion composition (X site = Cl <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-</sup> for blue emission, Br <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-</sup> for green emission, or I <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-</sup> for red emission) or size of QDs. Perovskite QDs are consisted almost entirely of inorganic elements, the energy levels of perovskite QDs are similar to the organic light-emitting materials, which lead to fabrication of device with similar structure of organic light-emitting devices (OLEDs). The external quantum efficiency (EQE) of LEDs based on CsPbX <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> QDs have rapidly increased from 0.1% to over 20% for past only few years.