gebhart/patrepeval huggingface dataset:
Crosslinked Chitosan Binder for Sustainable Aqueous Batteries (2022)

The increased percentage of renewable power sources involved in energy production highlights the importance of developing systems for stationary energy storage that satisfy the requirements of safety and low costs. Na ion batteries can be suitable candidates, specifically if their components are economic and safe. This study focuses on the development of aqueous processes and binders to prepare electrodes for sodium ion cells operating in aqueous solutions. We demonstrated the feasibility of a chitosan-based binder to produce freestanding electrodes for Na ion cells, without the use of organic solvents and current collectors in electrode processing. To our knowledge, it is the first time that water-processed, freestanding electrodes are used in aqueous Na ion cells, which could also be extended to other types of aqueous batteries. This is a real breakthrough in terms of sustainability, taking into account low risks for health and environment and low costs.
25 nJ passively mode-locked fiber laser at 1080 nm (2006)

We report a fiber laser that produces 25 nJ, sub-200 fs pulses, an energy 60% higher than previous reports. We attribute the improvement to increased pump power and spectral filtering by the oscillatorpsilas waveplates.
ChemInform Abstract: New and Effective Synthesis of 7‐Triethylsilylbaccatin III from 7β ,13α‐Bistriethylsiloxy‐1β,2α,10β‐trihydroxy‐9‐ oxo‐4(20),11‐taxadiene. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Energy transfer mechanism in Gd_2(SiO_4)O:Ce scintillators (1993)

The scintillation decay of cerium-doped gadolinium&#13;\noxyorthosilicate Gd_2(SiO_4)O:Ce is lengthened by the energy&#13;\ntransfer from Gd to Ce. To investigate the role of the Gd in&#13;\nthe scintillation processes, the Gd was partially replaced by&#13;\noptically inactive rare earth elements, Y and Lu, and the&#13;\neffective transfer rates from Gd to Ce were measured as a&#13;\nfunction of Gd and Ce concentrations using UV- and gamma-ray&#13;\nexcitations. The data clearly indicate the dilution of the Gd&#13;\nby the Y and the Lu further lengthens the migration time&#13;\nthrough the Gd in the energy transfer process from Gd to Ce.
Simple sequence repeats in Helicobacter canadensis and their role in phase variable expression and C-terminal sequence switching (2010)

Twenty-nine coding regions have been identified in the genome sequence of Helicobacter canadensis strain NCTC13241 that show variations in homopolymeric tract length in the bacterial population, indicative of phase variation. Five of these are potentially associated with promoter regions, which would lead to transcriptional phase variation. Translational phase variation usually switches expression of a gene ON and OFF due to the repeat region being located sufficiently close to the initiation codon for the resulting frame-shift to lead to a premature termination codon and stop the translation of the protein. Sixteen of the 29 coding regions have homopolymeric tracts characteristic of translational phase variation. For eight coding sequences with repeats located later in the reading frame, changes in the repeat tract length would alter the protein sequence at the C-terminus but not stop the expression of the protein. This mechanism of C-terminal phase variation has implications for stochastic switching of protein sequence in bacterial species that already undergo transcriptional and translational phase variation.
Flexible semantic processing of spatial prepositions (1998)

This article presents two experiments investigating whether language users spontaneously apply semantic extension principles to novel usages, or whether they treat word meanings as discrete, rigidly defined entities. In Experiment I, readers made a timed decision on the correctness of a sentence. Rejecting a cognitively plausible yet unattested extension of a preposition (*Peter is standing by the county) took longer and lead to more errors than rejecting a plainly incorrect usage of that preposition (*Peter is standing by the subtitle). This result was obtained for two novel extensions of two different prepositions. Experiment 2 included a preceding context in order to fix the referent of the target word and to exclude singular interpretations. The results were consistent with those of Experiment 1, although the overall number of errors dropped considerably. Taken together, these experiments indicate that, even in a task discouraging the use of flexible processing, subjects are not able to suppress the application of extension principles. We conclude that interpreting the meanings of words in a flexible way is an inherent property of a semantic processing system.
Assignment of the EPR Spectrum of 5,5-Dimethyl-1-pyrroline N-Oxide (DMPO) Superoxide Spin Adduct (2005)

[structure: see text] Spin trapping consists of using a nitrone or a nitroso compound to "trap" an unstable free radical as a long-lived nitroxide that can be characterized by electron paramagnetic resonance (EPR) spectroscopy. The formation of DMPO-OOH, the spin adduct resulting from trapping superoxide (O(2)(*)(-)) with 5,5-dimethyl-1-pyrroline N-oxide (DMPO), has been exploited to detect the generation of superoxide in a wide variety of biological and chemical systems. The 12-line EPR spectrum of DMPO-OOH has been either reported or mentioned in more than a thousand papers. It has been interpreted as resulting from the following couplings: A(N) approximately 1.42 mT, A(H)beta approximately 1.134 mT, and A(H)gamma(1H) approximately 0.125 mT. However, the DMPO-OOH EPR spectrum has an asymmetry that cannot be reproduced when the spectrum is calculated considering a single species. Recently, it was proposed that the 0.125 mT splitting was misassigned and actually results from the superimposition of two individual EPR spectra associated with different conformers of DMPO-OOH. We have prepared 5,5-dimethyl-[3,3-(2)H(2)]-1-pyrroline N-oxide (DMPO-d(2)), and we showed that the EPR spectrum of the corresponding superoxide spin adduct is composed of only six lines, in agreement with the assignment of the 0.125 mT splitting to a gamma-splitting from a hydrogen atom bonded to carbon 3 of DMPO. This result was supported by DFT calculations including water solvation, and the asymmetry of the DMPO-OOH EPR spectrum was nicely reproduced assuming a chemical exchange between two conformers.
Design and Implementation of Context Aware Cyber Physical System for Sustainable Smart Building (2018)

This article introduces a practical and real approach to the implementation of a cyber physical system for the intelligent management of energy consumption in a traditional building. The main objective of this research work has been to deploy a context aware cyber physical system to analyze the behavior of key physical parameters in order to optimize the energy consumption with a minimum degradation of the working conditions of the users. The scope of the project has been limited to design and develop a prototype to study the technical and economic viability of the implementation of this kind of technology. The paper also presents a detailed analysis on the electrical systems and their possibilities to increase the efficiency in terms of energy and cost savings. This is the case of the lighting system whose behavior has shown how a 3% of the energy consumption can be saved. The study conducted proves the current economical non-viability of cyber physical systems in traditional buildings for their energy management. Nevertheless, the non-developed nor marketed technologies which will allow their technical and economic viability have been identified and described.
Abstract 17576: Frequency, Timing and Co-Occurrence of Heart Failure Signs and Symptoms Among 50,625 Heart Failure Cases and Matched Controls in a Primary Care Population in the Months Preceding the Clinical Diagnosis of Heart Failure (2012)

The Framingham heart failure (HF) signs and symptoms are ubiquitous among primary care patients, leading to challenges in distinguishing a presentation attributable to HF versus other causes. A bet...
Deregulation of c- myc by Translocation of the α-Locus of the T-Cell Receptor in T-Cell Leukemias (1986)

Two human T-cell leukemias carrying a t(8;14)(q24;q11) chromosome translocation were studied for rearrangements and expression of the c-myc oncogene. For one leukemia, rearrangement was detected in a region immediately distal (3') to the c-myc locus; no rearrangements of c-myc were observed in the second case (DeF). However, studies with hybrids between human and mouse leukemic T cells indicated that in the leukemic cells of DeF, the breakpoint in chromosome 14 occurred between genes for the variable (V alpha) and the constant (C alpha) regions for the alpha chain of the T-cell receptor. The C alpha locus had translocated to a region more than 38 kilobases 3' to the involved c-myc oncogene. Since human c-myc transcripts were expressed only in hybrids carrying the 8q+ chromosome but not in hybrids containing the normal chromosome 8, it is concluded that the translocation of the C alpha locus 3' to the c-myc oncogene can result in its transcriptional deregulation.
Abstract 2503: Rational design of small-molecule immune checkpoints' inhibitors (2018)

Abstract Blocking the PD-1/PD-L1 and CTLA-4 pathways recently emerged as a ‘game changer' in cancer immunotherapy, leading to the selection of monoclonal-antibodies (MABs) targeting PD-1 as ‘drug of the year' for 2013. Although these antibodies restored exhausted T cells' function to recognize and kill tumor cells, these MABs have numerous disadvantages. These include their very high cost and very severe side effects. Our team has been focused on designing small molecule inhibitors for this pathway. Compared to available MAB therapies, our small molecules may offer a more affordable, more easily administered and better controlled treatment for a variety of cancers. Here, we demonstrate our efforts toward this goal and summarize our data on our promising compounds targeting the PD-1/PD-L1 and CTLA-4 pathways. Citation Format: Khaled Barakat. Rational design of small-molecule immune checkpoints' inhibitors [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2018; 2018 Apr 14-18; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2018;78(13 Suppl):Abstract nr 2503.
Cavity-Enhanced Lab-on-Fiber Technology: Toward Advanced Biosensors and Nano-Opto-Mechanical Active Devices (2019)

The integration of nanostructures able to manipulate light at the optical fiber tip is bringing the optical fibers to a renewed dimension since their beginnings. The past decade has seen unprecedented advancements in the lab-on-fiber technology field, pushed by the effective exploitation of nanoscale optical physics and supported by the improvement of nanofabrication techniques. In this context, here we report on a cavity enhanced lab-on-fiber optrode, which dramatically boosts the performances and widens the range of applications of the current lab-on-fiber systems, setting a new fundamental milestone along the roadmap of this technology. The “lab” integrated onto the fiber tip consists of a tunable optical cavity incorporating smart materials as the active layer. Specifically, the swelling/collapsing mechanism of multiresponsive microgels sandwiched in between gold layers induces the interplay between plasmonic resonances and cavity modes, according to optical cavity size. The combination of the optically resonant effects and microgels endows the optrode with the unique ability to work as both a sensor for detecting small molecules and a nano-opto-mechanical actuator triggered by light. In the specific case study here presented, we show that the device is able to detect glucose in solution, with a sensitivity improved by more than 1 order of magnitude compared to other state-of-the-art values. Moreover, we demonstrate that, by combining thermoplasmonics effects triggered by light coupled into the fiber and the microgel thermo-responsivity, it is possible to tune and control the optical cavity features, opening new avenues toward active nano-opto-mechanical actuators directly realized onto the fiber tip.
Threshold region performance of maximum likelihood direction of arrival estimators (2005)

This paper presents a performance analysis of the maximum likelihood (ML) estimator for finding the directions of arrival (DOAs) with a sensor array. The asymptotic properties of this estimator are well known. In this paper, the performance under conditions of low signal-to-noise ratio (SNR) and a small number of array snapshots is investigated. It is well known that the ML estimator exhibits a threshold effect, i.e., a rapid deterioration of estimation accuracy below a certain SNR or number of snapshots. This effect is caused by outliers and is not captured by standard techniques such as the Crame/spl acute/r-Rao bound and asymptotic analysis. In this paper, approximations to the mean square estimation error and probability of outlier are derived that can be used to predict the threshold region performance of the ML estimator with high accuracy. Both the deterministic ML and stochastic ML estimators are treated for the single-source and multisource estimation problems. These approximations alleviate the need for time-consuming computer simulations when evaluating the threshold region performance. For the special case of a single stochastic source signal and a single snapshot, it is shown that the ML estimator is not statistically efficient as SNR/spl rarr//spl infin/ due to the effect of outliers.
Refining tree-based state clustering by means of formal concept analysis, balanced decision trees and automatically generated model-sets (1999)

Decision tree-based state clustering has emerged in as the most popular approach for clustering the states of context dependent hidden Markov model based speech recognizers. The application of sets of phones, mainly phonetically motivated, that limit the possible clusters, results in a reasonably good modeling of unseen phones while it still enables to model specific phones very precisely whenever this is necessary and enough training data is available. Formal concept analysis, a young mathematical discipline, provides means for the treatment of sets and sets of sets that are well suited for further improving tree-based state clustering. The possible refinements are outlined and evaluated in this paper. The major merit is the proposal of procedures for the adaptation of the number of sets used for clustering to the amount of available training data, and of a method that generates suitable sets automatically without the incorporation of additional knowledge.
Solid-Phase Synthesis of Arginine-Containing Peptides by Guanidine Attachment to a Sulfonyl Linker (1997)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTSolid-Phase Synthesis of Arginine-Containing Peptides by Guanidine Attachment to a Sulfonyl LinkerH. Marlon Zhong, Michael N. Greco, and Bruce E. MaryanoffView Author Information Drug Discovery, The R. W. Johnson Pharmaceutical Research Institute, Spring House, Pennsylvania 19477 Cite this: J. Org. Chem. 1997, 62, 26, 9326–9330Publication Date (Web):December 26, 1997Publication History Received24 April 1997Published online26 December 1997Published inissue 1 December 1997https://doi.org/10.1021/jo970736nCopyright © 1997 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views531Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (112 KB) Get e-AlertsSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Crystal cleavage,Guanidine,Organic polymers,Organic synthesis,Peptides and proteins Get e-Alerts
A Multichannel Recursive Least-Squares Algorithm Based on a Kronecker Product Decomposition (2020)

In this paper, a multichannel recursive least-squares (RLS) algorithm is proposed for the identification of multiple-input single-output (MISO) systems. As compared to the conventional (multichannel) RLS algorithm, the proposed solution exploits a Kronecker product decomposition of the global impulse response, together with low-rank approximations. The gain is twofold, in terms of both performance and complexity. Simulations performed in the context of stereophonic acoustic echo cancellation indicate the appealing features of this algorithm.
Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors. (2001)

Mitochondrial DNA (mtDNA) mutations scattered through coding and noncoding regions have been reported in cancer. The mechanisms that generate such mutations and the importance of mtDNA mutations in tumor development are still not clear. Here we present the identification of a specific and highly polymorphic homopolymeric C stretch (D310), located within the displacement (D) loop, as a mutational hotspot in primary tumors. Twenty-two % of the 247 primary tumors analyzed harbored somatic deletions/insertions at this mononucleotide repeat. Moreover, these alterations were also present in head and neck preneoplastic lesions. We further characterized the D310 variants that appeared in the lung and head and neck tumors. Most of the somatic alterations found in tumors showed deletion/insertions of 1- or 2-bp generating D310 variants identical to constitutive polymorphisms described previously. Sequencing analysis of individual clones from lymphocytes revealed that patients with D310 mutations in the tumors had statistically significant higher levels of D310 heteroplasmy (more than one length variant) in the lymphocyte mtDNA as compared with the patients without D310 mutations in the tumor mtDNA. On the basis of our observations, we propose a model in which D310 alterations are already present in normal cells and achieve homoplasmy in the tumor through a restriction/amplification event attributable to random genetic drift and clonal expansion.
ChemInform Abstract: PERFLUOROALKYLATION OF THE 2‐NITROPROPYL ANION. EVIDENCE FOR AN SRN1 PROCESS (1983)

Abstract Aus 2‐Nitropropan (I) entsteht das Salz (II).
Tables S7-S8 from The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations—The Lung Cancer Mutation Consortium (LCMC2) (2023)

&lt;p&gt;Supplemental Table 7: Cases with two or more oncogenic driver alterations. Supplemental Table 8. Comparison of LCMC I and LCMC II.&lt;/p&gt;
Co-incorporation effects of O and Na with CulnS2 thin films (2000)

By using x-ray photoelectron spectroscopy we have examined changes in the electronic structure of CuInS2 thin films with co-incorporation of O and Na that raised up the photovoltaic performance of CdS/CuInS2 solar cells. The electron binding energies of both the core levels and valence band for the film with the co-incorporation were smaller by 0.9 eV than those for the film without the co-incorporation. For the co-incorporated film an increase in the spectral intensity of the valence band was observed below 1–6 eV from the Cu 3d10 nonbonding states, and it was due to both the Na s, p-S p hybridization and the In s-Op hybridization. The surface of the co-incorporated film can be expressed as (Cu, Na)In(S, O)2. The (Cu, Na)In(S, O)2 phase is related to the enlarged open-circuit voltage (0.75 eV) of n-CdS/p-CuInS2 solar cells.
"Special issue on RF and microwave Filters, Modelling and Design" (2007)

The current issue of the Journal is a Special Issue on “RF and Microwave Filters, Modelling and Design”. This special issue deals with the recent developments in passive and active including bi-mode and tunable filters, filter CAD tools, new filter structures and BAW filters. Index Terms – Microwave Filters, Passive and active Filters, Bi-mode Filters, CAD tools, BAW filters
Degradation of epidermal growth factor receptors by cathepsin L‐like protease: Inhibition of the degradation by c‐Ha‐ras gene products (1988)

Extract of NIH3T3 mouse fibroblasts contains a protease which can cleave epidermal growth factor receptor (EGF receptor). This protease was tentatively named cathepsin X and purified to near homogeneity. The characteristics of cathepsin X were similar to those of cathepsin L and the proteolytic activity of cathepsin X was inhibited by c-Ha-ras gene products.
Spatiotemporal Formation and Growth Kinetics of Polyelectrolyte Complex Micelles with Millisecond Resolution (2020)

We have directly observed the in situ self-assembly kinetics of polyelectrolyte complex (PEC) micelles by synchrotron time-resolved small-angle X-ray scattering, equipped with a stopped-flow device that provides millisecond temporal resolution. A synthesized neutral-charged diblock polycation and homopolyanion that we have previously investigated as a model charge-matched, core-shell micelle system were selected for this work. The initial micellization of the oppositely charged polyelectrolytes was completed within the dead time of mixing of 100 ms, followed by micelle growth and equilibration up to several seconds. By combining the structural evolution of the radius of gyration (<i>R</i><sub>g</sub>) with complementary molecular dynamics simulations, we show how the self-assemblies evolve incrementally in size over time through a two-step kinetic process: first, oppositely charged polyelectrolyte chains pair to form nascent aggregates that immediately assemble into spherical micelles, and second, these PEC micelles grow into larger micellar entities. This work has determined one possible kinetic pathway for the initial formation of PEC micelles, which provides useful physical insights for increasing fundamental understanding self-assembly dynamics, driven by polyelectrolyte complexation that occurs on ultrafast time scales.
Integrated multipurpose analog front-end for electrochemical ISFET sensors (2019)

Ion-Sensitive-Field-Effect-Transistors (ISFETs) are an alternative to the common glass electrode for pH sensing. They promise higher integration, easier manufacturing and are interesting for biological, medical and environmental applications. However, they require a different and slightly more complex readout circuit. We propose a new circuit based on a standard mixed-signal-processor with minimal required external components. The operating point of the ISFET is set with a servo loop in software using only the integrated DACs and opamps and an external resistor. With the internal ADC, feedback is provided for the software loop and the result is read. We compare this method with a fully analog ISFET readout circuit and show their equivalence. The new circuit provides some additional features, such as run time configurable operating point and channel type settings. The integrated MCU can also perform calibration and sensor diagnosis functionality and eases the integration in other systems and parallel operation of many units with its digital interfaces.