gebhart/patrepeval huggingface dataset:
Intelligent studios modeling space and action to control tv cameras (1997)

This article describes strategies to model the geometry and actions occurring in a performance space such as a TV studio. The basic assumption is that in such situations a script is available, providing contextual information that can be coupled with visual data from cameras monitoring the space. The integration of linguistic and visual information is accomplished through the use of approximate world models, a combination of symbolic data and geometrical 3-D models with low positional accuracy. Some commonsense reasoning is often required to infer visual and geometrical attributes from the script, and the article examines how simple inference rules are able to provide most of the necessary information. We also detail an application where an intelligent studio controls three automatic robotic cameras, producing video sequences with TV quality of framing.
Virtual Network Allocation (SDN) in Cloud Computing Using Evolutionary Algorithm (2019)

Resource allocation is a key process for cloud networks, as Infrastructure as a Service (IaaS) and Software as a Service (SaaS). These technologies are becoming increasingly common, with increasing adoption by users and industries around the world. To make the most efficient use of this technology, we propose an optimized evolutionary algorithm (Evolution Strategy - ES) to achieve the optimization of the allocation of cloud resources on a physical network with large computational demands (data processing). We investigated the possibility of reallocating resources randomly generated on an SDN network and host them in a flexible and balanced manner. This improves performance and permit to find a better allocation for the maximum use of resources, processing and continuity of service. We consider that unbalanced allocation can lead to big problems in the network, such as a not full utilization of resources or even a standstill. The allocations made by the evolutionary algorithm (EA) proven to be more efficient than the allocations made by AGA (auto adaptive genetic algorithm) and conventional mode (random allocation). The experiments also show that our method improves the allocation of resources by giving more balance to the network.
The effect of the amiodarone–warfarin interaction on anticoagulation quality in a single, high-quality anticoagulation center (2015)

Clinical trials have reported a low time in therapeutic range (TTR) in patients with atrial fibrillation treated with both warfarin andamiodarone. These trials included centers and countries with both high and low TTRs. What is the impact of amiodarone on the TTR in a single, high-quality anticoagulation clinic? TTR was assessed in amiodarone and nonamiodarone-treated patients from a University anticoagulation clinic. Baseline characteristics between patients ever-taking or never-taking amiodarone were similar, except more amiodarone patients were smokers (19.5 vs. 6.1%, P = 0.0031). The TTR calculated from 8901international normalized ratios (INRs) in 249 nonamiodarone patients with a mean follow-up of 34 ± 20 months (mean INR 36 ± 18) was 66 ± 16.6% compared with 61.3 ± 16.2% (P = 0.111) from 1455 INRs in 41 amiodarone-treated patients with a mean follow-up of 28 ± 20 months (mean INR 35 ± 22). Factors associated with a low TTR were male sex (P = 0.0013), smoker (P = 0.0048), and amiodarone use (P = 0.0374). A second on-treatment analysis, in which the TTR was calculated only during amiodarone therapy, resulted in similar findings; however, amiodarone did not emerge as a predictor of a low TTR. In 11 patients, the TTR prior to amiodarone (54.5 ± 22.2%) was not significantly different in the first 3 months (54.6 ± 33.4%) or after 3 months (67.2 ± 33.7%) of amiodarone. In a single high-quality anticoagulation center, anticoagulation quality, as measured by the TTR, can be comparable in amiodarone and nonamiodarone-treated patients.
Near and farfield of strip-shaped acoustic radiators (1979)

The acoustic radiation produced by baffled flat strip-shaped sources of infinite length is treated in detail. The nearfield intensity distribution, nearfield to farfield transition, and cylindrical farfield radiation is calculated for homogeneous radiator surface excitation; such beams are shown to partially focus at their last maximum of intensity. Farfield radiation is calculated for radiators with a Gaussian surface velocity distribution, for shaded transducers, and for arrays of strip-shaped sources. The use of such radiators in Doppler flow measuring systems is discussed.
Early prediction of preeclampsia in pregnancy with cell-free RNA (2022)

Liquid biopsies that measure circulating cell-free RNA (cfRNA) offer an opportunity to study the development of pregnancy-related complications in a non-invasive manner and to bridge gaps in clinical care<sup>1-4</sup>. Here we used 404 blood samples from 199 pregnant mothers to identify and validate cfRNA transcriptomic changes that are associated with preeclampsia, a multi-organ syndrome that is the second largest cause of maternal death globally<sup>5</sup>. We find that changes in cfRNA gene expression between normotensive and preeclamptic mothers are marked and stable early in gestation, well before the onset of symptoms. These changes are enriched for genes specific to neuromuscular, endothelial and immune cell types and tissues that reflect key aspects of preeclampsia physiology<sup>6-9</sup>, suggest new hypotheses for disease progression and correlate with maternal organ health. This enabled the identification and independent validation of a panel of 18 genes that when measured between 5 and 16 weeks of gestation can form the basis of a liquid biopsy test that would identify mothers at risk of preeclampsia long before clinical symptoms manifest themselves. Tests based on these observations could help predict and manage who is at risk for preeclampsia-an important objective for obstetric care<sup>10,11</sup>.
Fluence Rate‐Dependent Photobleaching of Intratumorally Administered Pc 4 Does not Predict Tumor Growth Delay (2012)

We examined effects of fluence rate on the photobleaching of the photosensitizer Pc 4 during photodynamic therapy (PDT) and the relationship between photobleaching and tumor response to PDT. BALB/c mice with intradermal EMT6 tumors were given 0.03 mg kg(-1) Pc 4 by intratumor injection and irradiated at 667 nm with an irradiance of 50 or 150 mW cm(-2) to a fluence of 100 J cm(-2). While no cures were attained, significant tumor growth delay was demonstrated at both irradiances compared with drug-only controls. There was no significant difference in tumor responses to these two irradiances (P = 0.857). Fluorescence spectroscopy was used to monitor the bleaching of Pc 4 during irradiation, with more rapid bleaching with respect to fluence shown at the higher irradiance. No significant correlation was found between fluorescence photobleaching and tumor regrowth for the data interpreted as a whole. Within each treatment group, weak associations between photobleaching and outcome were observed. In the 50 mW cm(-2) group, enhanced photobleaching was associated with prolonged growth delay (P = 0.188), while at 150 mW cm(-2) this trend was reversed (P = 0.308). Thus, it appears that Pc 4 photobleaching is not a strong predictor of individual tumor response to Pc 4-PDT under these treatment conditions.
The use of the frequency-dependent finite-difference time-domain method for induced current and SAR calculations for a heterogeneous model of the human body (1994)

This paper describes the use of the previously formulated frequency-dependent finite-difference time-domain ((FD)/sup 2/TD) method for analysis of an anatomically based heterogeneous man model exposed to ultra-wide-band electromagnetic pulse sources. The human tissues' electrical permittivities, /spl epsiv//sub i/*(/spl omega/) are described by Debye equations with two relaxation constants, and the equation D(t)=/spl epsiv/*(/spl omega/))E(t) is converted to a finite-difference equation along with the Maxwell's equations used by the standard FDTD method. Using a single run with a broad-band pulse excitation, the (FD)/sup 2/TD method is used to calculate mass normalized rates of energy deposition (specific absorption rates or SARs) and induced currents in the man model over a broad band of frequencies. Time-domain coupling of a representative ultrashort pulse of subnanosecond rise time and nanosecond pulse duration to the human body is also examined.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Protective effect of estrogen combined with aspirin against re-stenosis of vein graft (1992)

The protective effect of estrogen and aspirin against the re-stenosis of vein graft was studied in three groups of male cholesterol-fed rabbits autografted with femoral vein in one side of femoral artery. Group A(n=5) injected 1 mg/wk estrogen and ingested 160mg/wk aspirin, group B(n=5) only injected 1mg/wk estrogen and group C(n=5) ingested placebo for eight weeks. After eight weeks feeding with 1% cholesterol diet, these were slaughtered and grafts were removed. Grafts stayed patent 3 out of 5 in group A, 2 out of 4 in group B(one claggedi mmediately after transplantation), but all occluded with severe stenosis and thrombi in group C. In enzyme labeled-antibody method, macrophage existed partially and proliferation of smooth muscle cells inhibited to some extent in group A and B, but many macrophages existed and smooth muscle layers were replaced fibrous tissues in group C. This result reveals estrogen and aspirin are effective to inhibit re-stenosis of vein graft.
The effects of neuromodulation in a novel obese-prone rat model of detrusor underactivity (2017)

Obesity is a global epidemic associated with an increased risk for lower urinary tract dysfunction. Inefficient voiding and urinary retention may arise in late-stage obesity when the expulsive force of the detrusor smooth muscle cannot overcome outlet resistance. Detrusor underactivity (DUA) and impaired contractility may contribute to the pathogenesis of nonobstructive urinary retention. We used cystometry and electrical stimulation of peripheral nerves (pudendal and pelvic nerves) to characterize and improve bladder function in urethane-anesthetized obese-prone (OP) and obese-resistant (OR) rats following diet-induced obesity (DIO). OP rats exhibited urinary retention and impaired detrusor contractility following DIO, reflected as increased volume threshold, decreased peak micturition pressure, and decreased voiding efficiency (VE) compared with OR rats. Electrical stimulation of the sensory branch of the pudendal nerve did not increase VE, whereas patterned bursting stimulation of the motor branch of the pudendal nerve increased VE twofold in OP rats. OP rats required increased amplitude of electrical stimulation of the pelvic nerve to elicit bladder contractions, and maximum evoked bladder contraction amplitudes were decreased relative to OR rats. Collectively, these studies characterize a novel animal model of DUA that can be used to determine pathophysiology and suggest that neuromodulation is a potential management option for DUA.
Some Experiences on Dynamic Memory Management Refinement at System-Level for Multimedia Applications (2003)

Abstract — Nowadays, 3D multimedia applications have grown rapidly in number and consist of complex systems (e.g. 3D graphical processing or games) that process extensive amounts of data to create 3D images and results. This produces highcost and high-power consumption systems whereas a superior portability demands cheap and low-power consumption ones. In these multimedia applications, the dynamic memory subsystem is currently one of the main sources of power consumption and its inattentive management can affect severely the performance and power consumption of the whole system. In this paper, we illustrate a new system-level method to explore and refine the dynamic memory management of multimedia systems on current typical case studies, i.e. a relatively new 3D image reconstruction system and a 3D simulation game. This method is based on an analysis of the access pattern, amount of memory used and power consumption estimations. With this information, a phasewise exploration and refinement flow is used to optimize the system at the different phases of its hardware-oriented design process. As the results in the case studies show, our system-level method achieves great improvements in memory footprint, power consumption and performance for multimedia applications. I.
Sequential Activation and Deactivation of Protein Function Using Spectrally Differentiated Caged Phosphoamino Acids (2011)

Photolabile caging groups, including the 1-(2-nitrophenyl)ethyl (NPE) group, have been applied to probe many biological processes, including protein phosphorylation. Although studies with NPE-caged phosphoamino acids have provided valuable information, these investigations have been limited to the use of only one caged species in a single experiment. To expand the scope of these tools, we have developed an approach for sequentially uncaging two different phosphopeptides in one system, enabling interrogation of multiple phosphorylation events. We present the synthesis of [7-(diethylamino)coumarin-4-yl]methyl (DEACM)-caged phosphorylated serine, threonine, and tyrosine building blocks for Fmoc-based solid-phase peptide synthesis to allow convenient incorporation of these residues into peptides and proteins. Exposure of DEACM- and NPE-caged phosphopeptides to 420 nm light selectively releases the DEACM group without affecting the NPE-caged peptide. This then enables a subsequent irradiation event at 365 nm to remove the NPE group and liberate a second phosphopeptide. We demonstrate the versatility of this general sequential uncaging approach by applying it to control Wip1 phosphatase with two wavelengths of light.
Improving performance of multi-user OFDM systemsusingbit-wise interleaver (2001)

A new bit-wise interleaver is introduced for multi-user orthogonal frequency division multiplexing systems using frequency hopping. In addition to placing adjacent bits (belonging to one complex I/Q symbol) onto different subcarriers, they can be placed at different timeslots or different blocks. Furthermore, the interleaver can be adjusted adaptively based on the corresponding hopping pattern. The performance gain is investigated by simulations.
Highly Efficient Surface Relief Formation via Photoembossing of a Supramolecular Polymer (2008)

Abstract A new highly efficient photopolymer based on a supramolecular polymer was developed for creating surface relief structures in polymer thin films via a reaction/diffusion mechanism known as photoembossing. The effect of the photoinitiator content, the exposure dose, and developing temperature were investigated and the optimal settings were determined by differential scanning calorimetry (DSC) and confocal microscopy. It was found that a surface relief structure of 2.1 µm could be obtained in a 3 µm thin film, which is more than 2.5 times higher than can be achieved in the conventional polymer/monomer based photopolymer systems. magnified image
Population difference of two-level atomic system due to a running pulsed field (1975)

The method of multiple scales is used to derive an expression for the population difference in an absorbing atomic system due to a running pulsed field. The main contribution to this expression comes from a quasi-steady-state part which has the same functional form as the hole produced by a continuous running field, except that the saturation parameter contains the time dependence of the field. The expression includes also an oscillatory term and a quasisteady term, which decay with a rate that is equal to the inverse of the lifetime of the levels.
Microwave‐Assisted One‐Pot Synthesis of 2,3‐Disubstituted 3H‐Quinazolin‐4‐ones. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Using Cognitive Semantics to Integrate Perception and Motion in a Behavior-Based Robot (2008)

The ADAPT project is a collaboration of three universities building a unified architecture for mobile robots. The goal of this project is to endow robots with the full range of cognitive abilities, including perception, use of natural language, learning and the ability to solve complex problems. The perspective of this work is that such an architecture should be based on language and visualization. ADAPT is based on an the structure and semantics of language, and more specifically on algebraic linguistics and visualization of semantics. ADAPT organizes its knowledge using linguistic robot schemas, which implement linguistic units within a concurrent, distributed programming language. Each schema is associated with one or more 3D visualizations that provide its semantics. These visualizations are dynamic, and are composed within a virtual world to create ADAPTpsilas representation of itself and its environment.
Reduced cardiac hypertrophy and altered blood pressure control in transgenic rats with the human tissue kallikrein gene (2000)

To evaluate the cardiovascular actions of kinins, we established a transgenic rat line harboring the human tissue kallikrein gene, TGR(hKLK1). Under the control of the zinc-inducible metallothionein promoter, the transgene was expressed in most tissues including the heart, kidney, lung, and brain, and human kallikrein was detected in the urine of transgenic animals. Transgenic rats had a lower 24-h mean arterial pressure in comparison with control rats, which was further decreased when their diet was supplemented with zinc. The day/night rhythm of blood pressure was significantly diminished in TGR(hKLK1) animals, whereas the circadian rhythms of heart rate and locomotor activity were unaffected. Induction of cardiac hypertrophy by isoproterenol treatment revealed a marked protective effect of the kallikrein transgene because the cardiac weight of TGR(hKLK1) increased significantly less, and the expression of atrial natriuretic peptide and collagen III as markers for hypertrophy and fibrosis, respectively, were less enhanced. The specific kinin-B2 receptor antagonist, icatibant, abolished this cardioprotective effect. In conclusion, the kallikrein-kinin system is an important determinant in the regulation of blood pressure and its circadian rhythmicity. It also exerts antihypertrophic and antifibrotic actions in the heart.
ChemInform Abstract: Discovery of Betrixaban (PRT054021), N‐(5‐Chloropyridin‐2‐yl)‐2‐(4‐ (N,N‐dimethylcarbamimidoyl)benzamido)‐5‐methoxybenzamide, a Highly Potent, Selective, and Orally Efficacious Factor Xa Inhibitor. (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Ruthenium metallization for advanced interconnects (2016)

We demonstrate 10 nm half-pitch (HP) Ruthenium interconnects filled by atomic layer deposition (ALD). The resistivity and the cross-sectional area of Ruthenium interconnects were determined via the Matthiessen's rule method. We find that the resistivity of Ru was rather independent of the cross-sectional area of the interconnect, increasing from 12 µΩcm for larger lines to 15–17 µΩcm for cross-sectional areas of 200–300 nm2. 10 nm HP Ru lines showed no electromigration failures at 5 MA/cm2 and 300°C during 1000 hours. Time-dependent dielectric breakdown measurements indicated that Ruthenium does not require a diffusion barrier on both dense and porous low-κ dielectrics.
A Randomized Controlled Trial of Preoperative Intra-Aortic Balloon Pump in Coronary Patients With Poor Left Ventricular Function Undergoing Coronary Artery Bypass Surgery* (2013)

This study demonstrates that in patients undergoing nonemergent coronary operations, with a stable hemodynamic profile and a left ventricular ejection fraction less than 35%, the preincision insertion of intra-aortic balloon pump does not result in a better outcome. Given the possible complications of intra-aortic balloon pump insertion, and the additional cost of the procedure, this approach is not justified.
In Vitro Evaluation of Inhalable Verapamil-Rifapentine Particles for Tuberculosis Therapy (2016)

Recent studies have demonstrated that efflux pumps of Mycobacterium tuberculosis (M. tb) provide a crucial mechanism in the development of drug resistant to antimycobacterial drugs. Drugs that inhibit these efflux pumps, such as verapamil, have shown the potential in enhancing the treatment success. We therefore hypothesized that the combined inhaled administration of verapamil and a first-line rifamycin antibiotic will further improve the treatment efficacy. An inhalable dry powder consisting of amorphous verapamil and crystalline rifapentine with l-leucine as an excipient was produced by spray drying. The in vitro aerosol characteristic of the powder, its microbiological activity and stability were assessed. When the powder was dispersed by an Osmohaler, the total fine particle fraction (FPFtotal, wt % of particles in aerosol <5 μm) of verapamil and rifapentine was 77.4 ± 1.1% and 71.5 ± 2.0%, respectively. The combination drug formulation showed a minimum inhibitory concentration (MIC90) similar to that of rifapentine alone when tested against both M. tb H37Ra and M. tb H37Rv strains. Importantly, the combination resulted in increased killing of M. tb H37Ra within the infected macrophage cells compared to either verapamil or rifapentine alone. In assessing cellular toxicity, the combination exhibited an acceptable half maximal inhibitory concentration (IC50) values (62.5 μg/mL) on both human monocytic (THP-1) and lung alveolar basal epithelial (A549) cell lines. Finally, the powder was stable after 3 months storage in 0% relative humidity at 20 ± 3 °C.
Risk of Bowel Perforation in Patients Receiving Interleukin-2 After Therapy With Anti-CTLA 4 Monoclonal Antibody (2006)

Smith, Franz O. MD; Goff, Stephanie L. MD; Klapper, Jacob A. MD; Levy, Catherine RN; Allen, Tamika RN; Mavroukakis, Sharon A. RN; Rosenberg, Steven A. MD, PhD Author Information
The ice-nucleating activity of African mineral dust in the Caribbean boundary layer (2022)

Abstract. African mineral dust is transported many thousands of kilometres from its source regions, and, because of its ability to nucleate ice, it plays a major role in cloud glaciation around the globe. The ice-nucleating activity of desert dust is influenced by its mineralogy, which varies substantially between source regions and across particle sizes. However, in models it is often assumed that the activity (expressed as active sites per unit surface area as a function of temperature) of atmospheric mineral dust is the same everywhere on the globe. Here, we find that the ice-nucleating activity of African desert dust sampled in the summertime marine boundary layer of Barbados (July and August 2017) is substantially lower than parameterizations based on soil from specific locations in the Sahara or dust sedimented from dust storms. We conclude that the activity of dust in Barbados' boundary layer is primarily defined by the low K-feldspar content of the dust, which is around 1 %. We propose that the dust we sampled in the Caribbean was from a region in western Africa (in and around the Sahel in Mauritania and Mali), which has a much lower feldspar content than other African sources across the Sahara and Sahel.