gebhart/patrepeval huggingface dataset:
Design and fabrication of two-stack tandem-type all-phosphorescent white organic light-emitting diode for achieving high color rendering index and luminous efficacy (2016)

White organic light-emitting diodes (WOLEDs) are regarded as the general lighting source. Although color rendering index (CRI) and luminous efficacy are usually in trade-off relation, we will discuss about the optimization of both characteristics, particularly focusing on the spectrum of a blue emitter. The emission at a shorter wavelength is substantially important for achieving very high CRI (> 90). The luminous efficacy of a phosphorescent blue emitter is low as its color falls in the deeper blue range; however, that does not show any significant influence on the WOLEDs. WOLEDs with different blue dopants are compared to confirm the calculation of the CRI and luminous efficacy, and the optimized WOLEDs exhibit luminous efficacy of 38.3 lm/W and CRI of 90.9.
Evidence for a hydrogen atom transfer mechanism or a fast proton/electron transfer mechanism for monoamine oxidase (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEvidence for a hydrogen atom transfer mechanism or a fast proton/electron transfer mechanism for monoamine oxidaseRichard B. Silverman and Yury ZelechonokCite this: J. Org. Chem. 1992, 57, 23, 6373–6374Publication Date (Print):November 1, 1992Publication History Published online1 May 2002Published inissue 1 November 1992https://pubs.acs.org/doi/10.1021/jo00049a066https://doi.org/10.1021/jo00049a066research-articleACS PublicationsRequest reuse permissionsArticle Views160Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Assessing the potential of ride-sharing using mobile and social data (2014)

This paper assesses the potential of ride-sharing for reducing traffic in a city -- based on mobility data extracted from 3G Call Description Records (CDRs), for the cities of Madrid and Barcelona (BCN), and from OSNs, such as Twitter and Foursquare (FSQ), collected for the cities of New York (NY) and Los Angeles (LA). First, we analyze these data sets to understand mobility patterns, home and work locations, and social ties between users. Then, we develop an efficient algorithm for matching users with similar mobility patterns, considering a range of constraints, including social distance. The solution provides an upper bound to the potential decrease in the number of cars in a city that can be achieved by ride-sharing. Our results indicate that this decrease can be as high as 31%, when users are willing to ride with friends of friends.
Proliferative Changes in the Bronchial Epithelium of Former Smokers Treated With Retinoids (2007)

In per-subject analyses, treatment with 13-cis-RA and alpha-tocopherol, compared with placebo, was statistically significantly associated with reduced bronchial epithelial cell proliferation; treatment with 9-cis-RA was not. In per-site analyses, statistically significant associations were obtained with both treatments.
Development and Integration of Predictive Models for Manufacturing and Structural Performance of Carbon Fiber Composites in Automotive Applications (Final Report) (2020)

The goal of this project is to develop integrated, state-of-the-art, computational modeling tools based on an integrated computational materials engineering (ICME) methodology that are critically needed to enable structural carbon fiber (CF) applications in automobiles. These tools are designed to predict the manufacturing and structural performance of CF composites, including stochastic effects. During the first phase of the project, the manufacturing and structural performance tools, including a stochastic driver, were developed, calibrated, and validated against coupon and component level test results. For this project, from the manufacturing side, the development efforts were focused on high-pressure resin transfer molding (HP-RTM), a potentially game-changing manufacturing technology that is capable of reaching the 3-5-minute cycle time that is necessary for volume manufacturing of composites. On the structural performance side, the crashworthiness of CF structures was studied. Accordingly, computational tools were developed and validated. The resulting differences between the numerical predictions and the experimental results in the first phase of the project were required to be less than 15%. During the second phase of the project, the manufacturing and performance tools were integrated by mapping the manufacturing outcomes (e.g., fiber angles, residual stresses, degree of cure, and defects) into the structural models. Also, using the tools developed in this project, an automotive assembly currently manufactured in steel (2016 GM Malibu) was redesigned to be manufactured using advanced CF composites with the objective of comparing the performance of the CF assembly with the developed ICME model predictions. The weight, performance and cost of the CF assembly were compared with the baseline steel assembly as well. The CF underbody design was shown to be 30% lighter than the corresponding steel design. The CF underbody assembly withstood the side pole impact with less than half the intrusion for the steel assembly. Excellent correlations within 10% for both peak impact load and intrusion were observed between the numerical predictions and experimental results. Based on the cost models developed in the project, the cost increase per Kg saved was determined to be $22. The project team has prepared a total of 28 publications in various journals and conferences and broadly communicated the project results for the benefit of the composite industry. The project team has also prepared a total of 10 patent applications that were submitted to the US Patent and Trademark office.
Annealing Effect of Cermet Membranes on Hydrogen Permeability (2006)

Abstract Ni–SrCe0.8Yb0.2O3−δ cermet membranes are being developed to separate hydrogen from hydrogen-containing gas mixtures at high temperature. The hydrogen flux of an annealed membrane showed higher flux than that of an as-sintered membrane. The major contribution to overall flux was from ambipolar diffusion through the metal-to-oxide grain boundary. The higher hydrogen permeation flux of an annealed membrane may be understood by its larger metal grains and lower tortuosity, leading to a less-effective length for proton diffusion.
Avidin Binds to Condensed Chromatin (1977)

The protein avidin has been conjugated with fluorescein isothiocyanate and then used to treat cells and chromosome preparations. Fluorescence microscopy reveals that this protein is bound by areas of the specimen containing condensed chromatin.
Abstract 20134: Transcriptional Profiling Identifies Candidate Regulators of Neonatal Heart Regeneration (2014)

Some higher organisms, such as zebrafish and neonatal mice, are capable of complete and sufficient regeneration of the myocardium following injury, which is thought to occur primarily by proliferation of pre-existing cardiomyocytes. Although adult humans and adult mice lack this cardiac regeneration potential, there is great interest in understanding how regeneration can occur in the heart so that we can activate this process in humans suffering from heart failure. The aim of our study was to identify mechanisms by which mature, post-mitotic adult cardiomyocytes can re-enter the cell cycle to ultimately facilitate heart regeneration following injury. We derived a core transcriptional signature of injury-induced cardiomyocyte regeneration in mouse by comparing global transcriptional programs in a dynamic model of in vitro and in vivo cardiomyocyte differentiation and in an in vitro cardiomyocyte explant model, as well as a neonatal heart resection model. We identified a panel of transcription factors, growth factors, and cytokines, whose expression significantly correlated with the differentiated state of the cell in all datasets examined, suggesting that these factors play a role in regulating cardiomyocyte cell state. Furthermore, potential upstream regulators of core differentially expressed networks were identified using Ingenuity Pathway Analysis and we found that one predicted regulator, interleukin-13 (IL13), significantly induced cardiomyocyte cell cycle activity and STAT6/STAT3 signaling in vitro. siRNA knockdown experiments demonstrated that STAT3/periostin and STAT6 signaling are critical for cardiomyocyte cell cycle activity in response to IL13. These data reveal novel insights into the transcriptional regulation of mammalian heart regeneration and provide the founding circuitry for identifying potential regulators for stimulating cardiomyocyte cell cycle activity.
ATP-activated oligomerization as a mechanism for apoptosis regulation: Fold and mechanism prediction for CED-4 (2000)

Fold recognition algorithm FFAS (Rychlewski et al., Protein Sci, 2000;9:232-241) was used to match the nucleotide-binding adaptor shared by APAF-1, certain R gene products and CED-4 (NB-ARC domain) to the structure of the D2 domain of N-ethylemaleimide-Sensitive Fusion Protein and the delta; subunit of clamp loader of DNA polymerase III. The predicted structure consists of the p-loop ATP-binding domain, followed by two alpha-helical domains that regulate the oligomerization process. This prediction suggests a detailed molecular mechanism for the "induced proximity" hypothesis (Salvesen and Dixit, Proc Natl Acad Sci USA 1999;96:10964-10967) for CED3/caspase-9 activation by CED4/APAF-1 complex. According to this model, the ATP binding acts as a trigger in CED-4 oligomerization and the helical domain immediately following the ATP-binding domain provides additional mechanisms for regulation of the oligomerization process. This model explains most of known experimental data about CED-4-mediated caspase activation and, at the same time, suggest experiments that could test this hypothesis.
Relation between time reversal focusing and coherent backscattering in multiple scattering media: A diagrammatic approach (2004)

In this paper, we revisit one-channel time reversal (TR) experiments through multiple scattering media in the framework of the multiple scattering theory. The hyperresolution and the self-averaging property are retrieved. The developed formalism leads to a deeper understanding of the role of the ladder and most-crossed diagrams in a TR experiment and also establishes the link between TR and coherent backscattering (CBS). Especially, we show that when the initial source and the time reversal point are at the same location, the time-reversed amplitude is twice higher. Surprisingly, this enhancement is due to the ladder diagrams and not to the most-crossed ones, contrary to CBS. These theoretical predictions are confirmed by experimental results. The experiments are performed with ultrasonic waves propagating through a random collection of parallel steel rods.
A Control Strategy to Reduce Steering Torque for Stationary Vehicles Equipped with EPS (1999)

&lt;div class="htmlview paragraph"&gt;This paper proposes a new Electric Power Steering (EPS) control strategy that enables remarkable progress on steering maneuverability for stationary vehicles. Using a conventional controller, undesirable steering vibration prevented us from reducing steering torque. To eliminate this vibration, we developed a new control strategy based on damping for specified frequency using a motor angular-velocity estimator. We experimented with this proposed control algorithm using a test vehicle and confirmed that it enables reduced steering torque without any perceived vibration for drivers. Concerning the gradient of the assist-map, the proposed control strategy enabled more than three times higher compared with that of the same type vehicles on the market as the test vehicle. This proposed control strategy requires only the torque sensor signal, supply voltage and current to the motor, which are used in the conventional EPS systems, so no supplemental sensors are required.&lt;/div&gt;
Pathogenesis of muscle wasting in cancer cachexia: targeted anabolic and anticatabolic therapies (2010)

Targeted anabolic therapies aimed at preventing or reversing cancer cachexia might involve the combined use of androgens and amino acids working concurrently to enhance muscle protein synthesis and reduce muscle protein breakdown. Additional focused clinical studies are needed to identify muscle-specific targets or biomarkers for defined therapeutic approaches to slow or prevent cancer cachexia. In this review, we summarize the pathogenesis of cancer-related muscle wasting and discuss potential interventions at reversing or preventing cancer-related muscle loss.
Efficient Identification of Approximate Best Configuration of Training in Large Datasets (2019)

A configuration of training refers to the combinations of feature engineering, learner, and its associated hyperparameters. Given a set of configurations and a large dataset randomly split into training and testing set, we study how to efficiently identify the best configuration with approximately the highest testing accuracy when trained from the training set. To guarantee small accuracy loss, we develop a solution using confidence interval (CI)-based progressive sampling and pruning strategy. Compared to using full data to find the exact best configuration, our solution achieves more than two orders of magnitude speedup, while the returned top configuration has identical or close test accuracy.
Agonist derived molecular probes for A2 adenosine receptors (1989)

The adenosine agonist 2-(4-(2-carboxyethyl)phenylethylamino)-5'-N- ethylcarboxamidoadenos ine (CGS21680) was recently reported to be selective for the A2 adenosine receptor subtype, which mediates its hypotensive action. To investigate structure/activity relationships at a distal site, CGS21680 was derivatized using a functionalized congener approach. The carboxylic group of CGS21680 has been esterified to form a methyl ester, which was then treated with ethylenediamine to produce an amine congener. The amine congener was an intermediate for acylation reactions, in which the reactive acyl species contained a reported group, or the precursor for such. For radioiodination, derivatives of p-hydroxyphenylpropionic, 2-thiophenylacetic, and p-aminophenylacetic acids were prepared. The latter derivative (PAPA-APEC) was iodinated electrophilically using [125I]iodide resulting in a radioligand which was used for studies of competition of binding to striatal A2 adenosine receptors in bovine brain. A biotin conjugate and an aryl sulfonate were at least 350-fold selective for A2 receptors. For spectroscopic detection, a derivative of the stable free radical tetramethyl-1-piperidinyloxy (TEMPO) was prepared. For irreversible inhibition of receptors, meta- and para-phenylenediisothiocyanate groups were incorporated in the analogs. We have demonstrated that binding at A2 receptors is relatively insensitive to distal structural changes at the 2-position, and we report high affinity molecular probes for receptor characterization by radioactive, spectroscopic and affinity labelling methodology.
Hydrogen Sulfide and Carbon Dioxide Removal from Dry Fuel Gas Streams Using an Ionic Liquid as a Physical Solvent†‡ (2009)

The mole fraction solubilities (x*) and volumetric liquid-side mass-transfer coefficients (kLa) for H2S and CO2 in the ionic liquid, TEGO IL K5, (a quaternary ammonium polyether) were measured under different pressures (up to 30 bar) and temperatures (up to 500 K) in a 4 L ZipperClave agitated reactor. CO2 and N2, as single gases, and a H2S/N2 gaseous mixture were used in the experiments. The solubilities of H2S and CO2 were found to increase with pressure and decrease with temperature within the experimental conditions used. The H2S solubilities in the ionic liquid (IL) were greater than those of CO2 within the temperature range investigated (300−500 K) up to a H2S partial pressure of 2.33 bar. Hence, the IL can be effectively used to capture both H2S and CO2 from dry fuel gas stream within the temperature range from 300 to 500 K under a total pressure up to 30 bar. The presence of H2S in the H2S/N2 mixture created mass-transfer resistance, which decreased kLa values for N2. The kLa and x* values of CO2 were found to be greater than those of N2 in the IL, which highlight the stronger selectivity of this physical solvent toward CO2 than toward N2. In addition, within the temperature range from 300 to 500 K, the solubility and kLa of H2S in the IL were greater than those of CO2, suggesting that not only can H2S be more easily captured from dry fuel gas streams but also a shorter absorber can be employed for H2S capture than that for CO2.
Novel methodology for 130-nm DRAM cell mask size optimization (2000)

The possibility of 130-nm DRAM production with KrF lithography was investigated by simulation. First, the preferable exposure conditions that bring about sufficient exposure latitude (EL) for production were examined for each critical layer. Next, the effect of different mask errors of an attenuated phase shift mask on the EL was examined. In the experiments, a big difference was found on how much the errors reduced EL in the critical layers, and the EL of all patterns was found to change asymmetrically depending on the size comparison of completed mask and target design. In particular, if the contact hole size of Att. PSM is made smaller than design and exposure dosage becomes higher, EL decreases severely because of the sidelobe. As a result, selection of a size that is robust against mask errors instead of a size that exhibits the maximum exposure latitude without mask errors was found to maximize the practical EL in production. In this paper, we report on a novel methodology for 130-nm DRAM cell mask size optimization based on optical lithography simulation and dose-focus budget analyses. We also define the practical mask requirements for 130-nm DRAM production based on our simulation results.
Cover Picture: Nontoxic Membrane‐Active Antimicrobial Arylamide Oligomers (Angew. Chem. Int. Ed. 9/2004) (2004)

The amphiphilic nature of a highly selective antimicrobial arylamide oligomer is shown by the simulation of its conformation at a water/octane interface. Arginine end groups make this oligomer the most amphiphilic in the series studied and increase its overall hydrophobic moment. While the former property correlates with its low toxicity, the latter correlates with a high antimicrobial activity. More details are described in the Communication by DeGrado and co‐workers on page 1158 ff.
Identification of functional lox sites in the plastid genome (2003)

Our objective was to test whether or not cyclization recombination (CRE), the P1 phage site-specific recombinase, induces genome rearrangements in plastids. Testing was carried out in tobacco plants in which a DNA sequence, located between two inversely oriented locus of X-over of P1 (loxP) sites, underwent repeated cycles of inversions as a means of monitoring CRE activity. We report here that CRE mediates deletions between loxP sites and plastid DNA sequences in the 3'rps12 gene leader (lox-rps12) or in the psbA promoter core (lox-psbA). We also observed deletions between two directly oriented lox-psbA sites, but not between lox-rps12 sites. Deletion via duplicated rRNA operon promoter (Prrn) sequences was also frequent in CRE-active plants. However, CRE-mediated recombination is probably not directly involved, as no recombination junction between loxP and Prrn could be observed. Tobacco plants carrying deleted genomes as a minor fraction of the plastid genome population were fertile and phenotypically normal, suggesting that the absence of deleted genome segments was compensated by gene expression from wild-type copies. The deleted plastid genomes disappeared in the seed progeny lacking CRE. Observed plastid genome rearrangements are specific to engineered plastid genomes, which contain at least one loxP site or duplicated psbA promoter sequences. The wild-type plastid genome is expected to be stable, even if CRE is present in the plastid.
Carlons. Organic oligomers from condensation of carbon dinucleophiles with difunctional derivatives of carboxylic acids (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCarlons. Organic oligomers from condensation of carbon dinucleophiles with difunctional derivatives of carboxylic acidsLawrence B. Kool and George M. WhitesidesCite this: J. Am. Chem. Soc. 1988, 110, 1, 306–307Publication Date (Print):January 1, 1988Publication History Published online1 May 2002Published inissue 1 January 1988https://pubs.acs.org/doi/10.1021/ja00209a058https://doi.org/10.1021/ja00209a058research-articleACS PublicationsRequest reuse permissionsArticle Views98Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts