gebhart/patrepeval huggingface dataset:
The effect of angular dispersion on THz data transmission (2022)

One of the key distinctions between legacy low-frequency wireless systems and future THz wireless transmissions is that THz links will require high directionality, to overcome the large free-space path loss. Because of this directionality, optical phenomena become increasingly important as design considerations. A key example lies in the strong dependence of angular radiation patterns on the transmission frequency, which is manifested in many different situations including common diffraction patterns and the emission from leaky-wave apertures. As a result of this effect, the spectral bandwidth at a receiver is nonlinearly dependent on the receiver's angular position and distance from the transmitter. In this work, we explore the implications of this type of effect by incorporating either a diffraction grating or a leaky wave antenna into a communication link. These general considerations will have significant implications for the robustness of data transmissions at high frequencies.
Molecular mechanisms underlying regional variations of catecholamine-induced lipolysis in rat adipocytes (1995)

The mechanisms underlying catecholamine control of lipolysis were studied in rat white adipocytes from epididymal, retroperitoneal, and subcutaneous fat depots. Sensitivity of subcutaneous adipocytes to selective beta 3-adrenoceptor agonists was lower than that of internal adipocytes. beta 3-Adrenoceptor mRNA levels were lower in subcutaneous adipocytes. A decreased beta 1/beta 2-adrenoceptor-mediated lipolysis was also observed in these adipocytes, and the number of beta 1/beta 2-adrenoceptors was lower than in the internal adipocytes. The number of alpha 2-adrenoceptors was higher in subcutaneous adipocytes without a marked difference in alpha 2-adrenoceptor-mediated antilipolysis between the depots. Subcutaneous adipocytes were also characterized by a lower maximal lipolytic response to drugs acting at different levels of the lipolytic cascade, suggesting differences at the postreceptor level. Lower hormone-sensitive lipase activity and mRNA levels in subcutaneous adipocytes were in agreement with the lipolysis data. These results suggest that the pattern of expression of the genes of the lipolytic pathway varies with the anatomic location of the fat depot.
Three-dimensional culture of human keratinocytes on a dermal equivalent as a model system to study environmental modulation of epidermal physiology in vitro: effect of air-exposure (1986)

Journal Article Three‐dimensional culture of human keratinocytes on a dermal equivalent as a model system to study environmental modulation of epidermal physiology in vitro: effect of air‐exposure Get access D. ASSELINEAU, D. ASSELINEAU Centre International de Recherches Dermatologiques (CIRD), Sophia Antipolis, 06565 Valbonne, France Dr D.Asselineau. Search for other works by this author on: Oxford Academic Google Scholar B.A. BERNARD, B.A. BERNARD Centre International de Recherches Dermatologiques (CIRD), Sophia Antipolis, 06565 Valbonne, France Search for other works by this author on: Oxford Academic Google Scholar C. BAILLY, C. BAILLY Centre International de Recherches Dermatologiques (CIRD), Sophia Antipolis, 06565 Valbonne, France Search for other works by this author on: Oxford Academic Google Scholar Y.M. DARMON Y.M. DARMON Centre International de Recherches Dermatologiques (CIRD), Sophia Antipolis, 06565 Valbonne, France Search for other works by this author on: Oxford Academic Google Scholar British Journal of Dermatology, Volume 115, Issue s31, 1 August 1986, Pages 126–127, https://doi.org/10.1111/j.1365-2133.1986.tb02121.x Published: 01 August 1986
Field-emission properties of molybdenum disulfide nanotubes (2003)

The field-emission (FE) properties of molybdenum disulfide nanotubes (NTs) are reported for the single-tip geometry. Reproducibly stable FE currents in excess of 10 μA were measured from single NT tips in vacuum of 10−7 mbar. Valuable characteristics of the nanotube material are ease of processing and reproducibility of the FE properties.
iNOS expression in dystrophinopathies can be influenced by somatic gene transfer of dystrophin/utrophin (2000)

Abstract Background: Nitric oxide (NO) is an inorganic gas pro-duced by a family of NO synthase (NOS) proteins. Thepresence and the distribution of inducible-NOS (NOS IIor iNOS), and NADPH-diaphorase (NADPH-d), a markerfor NOS catalytic activity, were determined in muscle sec-tions from control, DMD, and BMD patients. Materials and Methods: NADPH-d reactivity, iNOS- andnNOS (NOS I)-immunolocalization were studied in mus-cles from mdx mice before and after somatic gene transferof dystrophin or utrophin. Results: In control patients, few ﬁbers ( 2%) demon-strated focal accumulation of iNOS in sarcolemma. InDMD patients, a strong iNOS immunoreactivity was ob-served in some necrotic muscle ﬁbers as well as in somemononuclear cells, and regenerating muscle ﬁbers had dif-fusely positive iNOS immunoreactivity. In DMD patients, Address correspondence and reprint requests to: James M.Wilson, M.D., Ph.D. Institute for Human Gene Therapy, 204Wistar Institute, 3601 Spruce Street, Philadelphia, PA 19104-4268, USA. Phone: (215) 898-3000. Fax: (215) 898-6588.E-mail: wilsonjm@mail.med.upenn.edu
Compounds and Their Use as BACE Inhibitors (2012)

Biological Target: -secretase (BACE)
Working area, safety zones, and angles of approach for posterior C-1 lateral mass screw placement: a quantitative anatomical and morphometric evaluation (2007)

The anatomical configuration of the atlas and vertebral artery (VA) varied considerably among the cadaveric specimens. The heights of the C-1 pedicle, posterior arch, and posterior lamina determine the posterior working area available for screw placement. The inferior insertion of the posterior arch may have to be drilled to increase this working area, but doing so risks injury to the VA. A dense venous plexus with multiple anastomoses may cover the screw entry site, potentially obscuring the operative view and increasing the risk of hemorrhage.
Tailoring the spectral response of add/drop single and multiple resonators in silicon-on-insulator (2009)

Channel dropping waveguide filters based on single and multiple resonators in silicon-on-insulator (SOI) technology are of great interest due to their compactness and high wavelength selectivity, which is a desirable feature for photonic modulators, detectors, and other optically integrated components in telecommunication systems, in particular for wavelength division multiplexing (WDM) systems. Particular advantage of these filters is that they are capable of producing relatively large free spectral range (FSR) as well as narrow 3-dB bandwidth of the filter resonances. Herein we report experimental results and discuss the possibility of designing mono-mode and (nearly) polarization independent SOI ring and racetrack resonators with the FSR in excess of 30 nm.
Performance evaluation of different antenna array approaches for 3G CDMA uplink (2002)

One approach to solve the coverage problem in 3/sup rd/ generation CDMA macro cells is to increase the number of receiving antennas at a base station. Antenna gain, diversity gain or both can be increased compared to conventional solutions. The relative performance of maximal-ratio combining, MRC, interference-rejection combining, IRC, fixed beam method (analog beamforming) and higher-order sectorization were studied. It was found out that the link level performance of different approaches depends mainly on the radio channel characteristics and on the particular multiple access interference scenario. In case of a large number of low-bit-rate users sectorization performs best in the macro cell channel giving 2.7-5.3 dB gain compared to 2-antenna MRC with 4-8 antennas. If only very few high-bit-rate interfering users are present and fractional loading is 50%. IRC gives best results giving a relative gain of 2.5-4.8 dB.
47.5L: Late‐News Paper : Highly Efficient White OLEDs Using RGB Fluorescent Materials (2007)

Abstract A three‐component white OLED device using fluorescent materials was developed for full‐color displays. Very high power‐efficiency of 17 lm/W@10mA/cm 2 and long lifetime over 30,000hr@1,000cd/m 2 were achieved by using new carrier transport materials with high mobility. Power consumption and half lifetime of a 2.2″ QVGA full‐color display were estimated by simulation to be about 200mW(200cd/m 2 ,100%ON) by combining the device with top‐emission structure. This value is comparable to the state of the art of LCDs.
Synthesis of a Cyclic Melanotropic Peptide Exhibiting Both Melanin-Concentrating and -Dispersing Activities (1984)

A putative melanin-concentrating hormone was synthesized. This peptide, H-Asp-Thr-Met-Arg-Cys-Met-Val-Gly-Arg-Val-Tyr-Arg-Pro-Cys-Trp-Glu-Val-OH , stimulates melanin granule aggregation within teleost melanocytes at nanomolar concentrations as does the natural purified teleost pituitary preparation. In addition, this peptide stimulates melanin granule dispersion within melanocytes of frogs and lizards. The peptide has about one six-hundredth of the activity of alpha-melanocyte-stimulating hormone on frog and lizard melanocytes and is a full agonist.
Identification of Low-Abundance Cancer Biomarker Candidate TIMP1 from Serum with Lectin Fractionation and Peptide Affinity Enrichment by Ultrahigh-Resolution Mass Spectrometry (2011)

As investigating a proteolytic target peptide originating from the tissue inhibitor of metalloproteinase 1 (TIMP1) known to be aberrantly glycosylated in patients with colorectal cancer (CRC), we first confirmed that TIMP1 is to be a CRC biomarker candidate in human serum. For this, we utilized matrix-assisted laser desorption/ionization (MALDI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometry (MS) showing ultrahigh-resolution and high mass accuracy. This investigation used phytohemagglutinin-L(4) (L-PHA) lectin, which shows binding affinity to the β-1,6-N-acetylglucosamine moiety of N-linked glycan on a protein, to compare fractionated aberrant protein glycoforms from both noncancerous control and CRC serum. Each lectin-captured fraction containing aberrant glycoforms of TIMP1 was digested by trypsin, resulting in the tryptic target peptide, representative of the serum glycoprotein TIMP1. The resulting target peptide was enriched using a stable isotope standard and capture by the antipeptide antibody (SISCAPA) technique and analyzed by a 15 T MALDI FTICR mass spectrometer with high mass accuracy (Δ < 0.5 ppm to the theoretical mass value of the target peptide). Since exact measurement of multiplex isotopic peaks of the target peptide could be accomplished by virtue of high mass resolution (Rs > 400,000), robust identification of the target peptide is only achievable with 15 T FTICR MS. Also, MALDI data obtained in this study showed that the L-PHA-captured glycoforms of TIMP1 were measured in the pooled CRC serum with about 5 times higher abundance than that in the noncancerous serum, and were further proved by MRM mass analysis. These results confirm that TIMP1 in human serum is a potent CRC biomarker candidate, demonstrating that ultrahigh-resolution MS can be a powerful tool toward identifying and verifying potential protein biomarker candidates.
Thermoplastic, rubber-like marine antifouling coatings with micro-structures via mechanical embossing (2020)

New processing routes and materials for non-biocidal, antifouling (AF) coatings with an improved performance are currently much sought after for a range of marine applications. Here, the processing, physical properties and marine AF performance of a fluorinated coating based on a thermoplastic (non-crosslinked) fluorinated polymer are reported. It was found that the addition of lubricating oil and hydrodynamic drag reducing microstructures improved the AF properties substantially, i.e. the settlement of a marine biofilm, containing mixed microalgae including diatoms, was reduced to low levels. More importantly, the remaining fouling was removed from the coatings at low hydrodynamic shear rates and promising AF properties were obtained. Moreover, additional potential benefits were revealed originating from the thermoplastic nature of the coating material which might result in significant cost reductions.
Benfotiamine Prevents Macro- and Microvascular Endothelial Dysfunction and Oxidative Stress Following a Meal Rich in Advanced Glycation End Products in Individuals With Type 2 Diabetes (2006)

Our study confirms micro- and macrovascular endothelial dysfunction accompanied by increased oxidative stress following a real-life, heat-processed, AGE-rich meal in individuals with type 2 diabetes and suggests benfotiamine as a potential treatment.
The application of smart structures toward feedback suppression in amplified acoustic guitars (2003)

Smart structures technology can be applied to amplified acoustic guitars to prevent instability resulting from acoustic feedback. This work presents a coupled model of the guitar dynamics and the acoustic feedback mechanism, and explains how a simple control loop using a piezoceramic actuator can be used to reduce the effects of acoustic feedback. In addition to model simulations, experimental results using a real system and a simple controller are presented. The results show that a significantly higher (7-dB) guitar output can be achieved before instability, without detrimentally affecting the amplified and un-amplified guitar response.
Numerical Modeling of Automotive Exhaust Catalysts (2011)

&lt;div class="section abstract"&gt;With a view to application of model base development to exhaust catalyst design, a numerical model for catalytic reaction was formulated so as to be able to predict tailpipe emission during test mode running. In order to grasp the catalytic reaction characteristics, catalyst characteristics test using catalyst test pieces and synthetic gas was conducted and the basic reaction that takes place inside the exhaust catalyst was modeled by employing the 3 overall reaction models: Arrhenius model, competitive adsorption model, and adsorption model. By using the formulated numerical catalyst model, tailpipe emission estimation for a gasoline engine vehicle was carried out, and an estimated accuracy of within ±10% error range from the actual measurement was realized for all of CO, HC, and NO.&lt;/div&gt;
A novel readout circuit for an OTFD gas sensor with a new front-end trans-impedance amplifier (2011)

The study proposes a new readout circuit for an organic gas sensor. The readout circuit consists of a preamplifier, a sample and hold circuit and a differential current amplifier. A preamplifier composed of trans-impedance to convert the output current of a gas sensor into voltage. The sample and hold circuit memorizes various voltages according to distinct designed time instants in a target gas environment. At the same time it is equipped with the advantage of repeated detections by the controlling signals which determine the frequency of switch. The differential current is amplified by a differential current amplifier and is attributable to the voltages of sample and hold circuits using current mirror framework. Flowing through the resistance load, the differential current is converted into output voltage. A microprocessor control unit (MCU) acquires and stores the outputs in order to determine gas concentration database of pre-measured which are contrast. The designed circuit is accomplished by Taiwan Semiconductor Manufacturing Company (TSMC) 0.35μm 2P4M 3.3V mixed-signal CMOS process.
Two-degree-of-freedom control with robust feedback control for hard disk servo systems (1999)

A two-degree-of freedom (2 DOF) control structure is proposed for read/write head servo systems of hard disk drives (HDDs). This structure is applied to both track seeking and track following, and makes mode switches found in conventional HDD servo systems unnecessary. Two innovative features introduced in the paper are: 1) a new method for generating the reference signal for track seeking and 2) two robust feedback control schemes for rejection of disturbances; one scheme uses a disturbance observer (DOB), and the other uses adaptive robust control (ARC). Simulation results show that the 2 DOF structure with ARC provides better performance than either the conventional servo system with mode switches or the 2 DOF structure with DOB. Experimental results show the advantage of the new reference generation method and the use of the DOB-based robust controller.
CB4-02: Validation of a Natural Language Processing Protocol for Detecting Heart Failure Signs and Symptoms in Electronic Health Record Text Notes (2012)

HMORN 2012 -Selected Abstracts procedure was CT scan, of which 132 (32%)were potentially redundant, for a rate of 7.4% (5.0-10.6%) per 100,000 member months. Rates will be calculated for a similar period following the HIE implementation and compared to baseline rates to assess the impact. Discussion: The HIE represents a new tool that can potentially reduce the rates of redundant testing in the ED setting. The process of defining redundant tests is a critical component of this kind of analysis. More work is needed in this area to define, standardize, and validate the "rules" for categorizing tests as redundant.
Calmodulin‐dependent protein kinase II mediates signal transduction in apoptosis (1997)

The present studies describe a new function for calmodulin-dependent protein kinase II (CaM-KII) in signal transduction leading to apoptosis. Both tumor necrosis factor alpha (TNF) and UV light rapidly stimulated Ca2+-independent activity of CaM-KII in the monocytic leukemia, U937. Two mechanistically different inhibitors of CaM-KII blocked activation of CaM-KII and prevented DNA fragmentation and death. Activation of CaM-KII during apoptosis and inhibition of DNA fragmentation by the two CaM-KII inhibitors were reproduced in several other lines including KGla, HL-60, and YAC-1. However, K562, which is relatively resistant to apoptosis induced by either TNF or UV light, did not activate CaM-KII in response to these stimuli. A variant derived from U937 that is resistant to TNF- or UV light-induced apoptosis also lacked a CaM-KII response. Activation of Cam-KII was blocked by two protease inhibitors, VAD-fmk and TPCK, but not by other inhibitors of serine proteases. Both inhibitors of CaM-KII and the protease inhibitors blocked activation of AP24, a serine protease originally isolated from apoptotic cells that induces DNA fragmentation in nuclei. Our evidence supports a model in which proteolytic activity functions upstream of CaM-KII. This kinase then leads to activation of AP24, which transmits signals to the nucleus to initiate DNA fragmentation.
It's alive! continuous feedback in UI programming (2013)

Live programming allows programmers to edit the code of a running program and immediately see the effect of the code changes. This tightening of the traditional edit-compile-run cycle reduces the cognitive gap between program code and execution, improving the learning experience of beginning programmers while boosting the productivity of seasoned ones. Unfortunately, live programming is difficult to realize in practice as imperative languages lack well-defined abstraction boundaries that make live programming responsive or its feedback comprehensible. This paper enables live programming for user interface programming by cleanly separating the rendering and non-rendering aspects of a UI program, allowing the display to be refreshed on a code change without restarting the program. A type and effect system formalizes this separation and provides an evaluation model that incorporates the code update step. By putting live programming on a more formal footing, we hope to enable critical and technical discussion of live programming systems.
Comparison of Electrical Performance of Co-Integrated Forksheets and Nanosheets Transistors for the 2nm Technological Node and Beyond (2021)

Forksheet devices have been recently proposed to further reduce the n-to-p spacing/footprint of transistors on wafer. In this work, we report on a systematic comparison of DC performance of Forksheets and Nanosheets transistors (with relevant dimensions of 23nm width and 7nm thickness) co-integrated on the same wafers. It is shown that the short channel control and transport properties (from Room Temperature up to 125°C) are comparable down to LG=22nm. We also show that gate stack reliability does not suffer from the SiN deposition and etch back of the Forksheet dielectric wall process. Additionally, it is shown that both Forksheets and Nanosheets exhibit good performance for analog applications, with good intrinsic voltage gain down to short gate lengths and excellent Low Frequency Noise levels. The strain boosters options with Forksheets are also investigated by TCAD and it is shown that the average stress induced by the S/D strain boosters does not suffer from the wall presence, making Forksheets promising candidates for further transistors downscaling.
Using a Heterogeneous Linguistic Network for Word Sense Induction and Disambiguation (2016)

Linguistic Networks are structures that allow us to model the characteristics of human language through a graph-like schema. This kind of modelization has proven to be useful while dealing with natural language processing tasks. In this paper, we first present and discuss the state of the art of recent semantic relatedness methods from a network-centric point of view. That is, we are interested in the types of networks used to solve practical semantic tasks. In order to address some of the short-comings in the studied approaches, we propose a hybrid linguistic structure that takes into account lexical and syntactical language information. We show our model’s practicality with a proof of concept: we set to solve word sense disambiguation and induction while using the presented network schema. Our modelization aims to shed light into ways of combining distinct types of linguistic information in order to take advantage of each of its components’ unique characteristics.
Quality of Life and Outcomes After Pancreaticoduodenectomy (2000)

This is the largest single-institution experience assessing QOL after pancreaticoduodenectomy. These data demonstrate that as a group, patients who survive pancreaticoduodenectomy have near-normal QOL scores. Many patients report weight loss and symptoms consistent with pancreatic exocrine and endocrine insufficiency. Most patients have QOL scores comparable to those of control patients and can function independently in daily activities.
Modeling of surface mechanical behaviors of soft elastic solids: theory and examples (2020)

Surfaces of soft solids can have significant surface stress, extensional modulus and bending stiffness. Previous theoretical studies have usually examined cases in which both the surface stress and bending stiffness are constant, assuming small deformation. In this work we consider a general formulation in which the surface can support large deformation and carry both surface stresses and surface bending moments. We demonstrate that the large deformation theory can be reduced to the classical linear theory (Shuttleworth equation). We obtain exact solutions for problems of an inflated cylindrical shell and bending of a plate with a finite thickness. Our analysis illustrates the different manners in which surface stiffening and surface bending stabilize these structures. We discuss how the complex surface constitutive behaviors affect the stress field of the bulk. Our calculation provides insights into effects of strain-dependent surface stress and surface bending in the large deformation regime, and can be used as a model to implement surface finite elements to study large deformation of complex structures.
Fabry-Perot intensity modulator with integrated Bragg reflectors in Ti:LiNbO 3 (2005)

A Fabry-Perot electro-optic intensity modulator in Ti:LiNbO3 utilising surface integrated Bragg reflectors is demonstrated. A modulation depth of 96% at 1542 nm wavelength is obtained, with a voltage-length product value which is a factor of 4.4 smaller than for a polarisation intensity modulator of the same switching voltage.