gebhart/patrepeval huggingface dataset:
Microdischarge-Based Sensors and Actuators for Portable Microsystems: Selected Examples (2012)

This paper describes the use of microdischarges as transducing elements in sensors and actuators. Chemical sensing of gases and liquids, pressure sensing in harsh environments, on-chip pressure regulation, and radiation detection methods are described. The devices targeted for these applications are presented from the perspective of the ease of integration into portable microsystems, with emphasis on compactness, power consumption, and the ability to operate over a wide range of temperatures and pressures. Performance results and other important integration considerations, such as manufacturing approaches and device packaging methods, are described for selected examples.
Design of microspectrometers (2003)

We review several spectrometer designs that use adaptive space-variance to reduce the total collected data and increase information content. We show a conceptual diagram of a simple space-variant spectrometer with adjustable dispersion. The spectrometer is used in imaging mode to disperse a complete line of object points simultaneously in the output plane. The MEMS mirrors in the input plane are designed to change the light path through the spectrometer on a pixel-by-pixel basis.
Sustained Attentional States Require Distinct Temporal Involvement of the Dorsal and Ventral Medial Prefrontal Cortex (2016)

Attending the sensory environment for cue detection is a cognitive operation that occurs on a time scale of seconds. The dorsal and ventral medial prefrontal cortex (mPFC) contribute to separate aspects of attentional processing. Pyramidal neurons in different parts of the mPFC are active during cognitive behavior, yet whether this activity is causally underlying attentional processing is not known. We aimed to determine the precise temporal requirements for activation of the mPFC subregions during the seconds prior to cue detection. To test this, we used optogenetic silencing of dorsal or ventral mPFC pyramidal neurons at defined time windows during a sustained attentional state. We find that the requirement of ventral mPFC pyramidal neuron activity is strictly time-locked to stimulus detection. Inhibiting the ventral mPFC 2 s before or during cue presentation reduces response accuracy and hampers behavioral inhibition. The requirement for dorsal mPFC activity on the other hand is temporally more loosely related to a preparatory attentional state, and short lapses in pyramidal neuron activity in dorsal mPFC do not affect performance. This only occurs when the dorsal mPFC is inhibited during the entire preparatory period. Together, our results reveal that a dissociable temporal recruitment of ventral and dorsal mPFC is required during attentional processing.
ChemInform Abstract: Oral, Direct Thrombin and Factor Xa Inhibitors: The Replacement for Warfarin, Leeches, and Pig Intestines? (2011)

Abstract Review: 74 refs.
Designed CO2‐Philes Stabilize Water‐in‐Carbon Dioxide Microemulsions (2006)

Wasser eingewickelt: Zwei nichtfluorierte CO2-phile Tenside erzeugten Wasser-in-Kohlendioxid-Mikroemulsionsdispersionen. Aus einer genauen Analyse der Hochdruck-Kleinwinkel-Neutronenbeugungsdaten ergeben sich Belege für die Bildung kugelförmiger D2O-Nanotröpfchen (rot), die durch Tensidmonoschichten (Linien) stabilisiert und in CO2 (gelb in der schematischen Streulängendichte(sld)-Auftragung) dispergiert sind.
Targeted Molecular Imaging of Tumors in Intact Animals Using Tumor Endothelium Homing Peptides (2005)

s: Abstracts for the 20th Annual Scientific Meeting of the International Society for Biological Therapy of Cancer (Primary Authors are Italicized): ANGIOGENESIS
ChemInform Abstract: SEPARATION OF CIS DIOLS FROM ISOMERIC CIS‐TRANS MIXTURES BY SELECTIVE COUPLING TO A REGENERABLE SOLID SUPPORT (1977)

Abstract Polymere Boronsäuren (I), speziell auf Basis eines schwach vernetzten Polystyrols, das nach Bromierung über eine Behandlung mit Butyllithium und anschließend mit Tributylborat erhalten werden kann, werden zur Trennung von Glykol‐Gemischen eingesetzt, wobei ein Stereoisomeres mit der Boronsäure ein Cyclokondensat bildet, während das andere Isomere abgetrennt werden kann.
Discovering Rules from Disk Events for Predicting Hard Drive Failures (2009)

Detecting impending failure of hard disks is an important prediction task which might help computer systems to prevent loss of data and performance degradation. Currently most of the hard drive vendors support self-monitoring, analysis and reporting technology (SMART) which are often considered unreliable for such tasks. The problem of finding alternatives to SMART for predicting disk failure is an area of active research. In this paper, we consider events recorded from live disks and show that it is possible to construct decision support systems which can detect such failures. It is desired that any such prediction methodology should have high accuracy and ease of interpretability. Black box models can deliver highly accurate solutions but do not provide an understanding of events which explains the decision given by it. To this end we explore rule based classifiers for predicting hard disk failures from various disk events. We show that it is possible to learn easy to understand rules, from disk events, which have extremely low false alarm rates on real world data.
Development of non-fluorine superhydrophobic textiles using polypropylene resins (2019)

This study aims to develop environment-friendly superhydrophobic textiles forming nanoparticles of polypropylene that have intrinsically low surface energy, and thus achieving the requirements for superhydrophobicity, such as hierarchical roughness and low surface energy at once. This work mainly studies the influences of tacticity (isotactic, atactic), concentration (10, 20, 30 and 40 mg/ml), drying temperature (30℃ and 70℃) and the mixing ratio of the solvent/non-solvent (9:1, 8:2, 7:3 and 6:4) on the coating morphology and wettability. In the case of isotactic polypropylene, the optimal condition showing the water contact angle of 173° and the water shedding angle of 4° was at 70℃ drying temperature, 30 mg/ml concentration and 6:4 solvent/non-solvent mixing ratio. Amorphous polypropylene showed the water contact angle of 163° and the water shedding angle of 9° at the condition of 30℃ drying temperature, 40 mg/ml concentration and 8:2 solvent/non-solvent mixing ratio. It was revealed that superhydrophobicity by amorphous polypropylene was exhibited at lower drying temperature and lower mixing ratio for the non-solvent. This is attributed to the different evaporation temperature or speed of the solvent/non-solvent mixing according to the tacticity of polypropylene. This study demonstrated that environmental-friendliness was improved in that superhydrophobic textiles were developed without fluorine compounds, maintaining vapor permeability. This study also developed a finishing method using amorphous polypropylene under a mild condition in terms of drying temperature and solvent toxicity, which is expected to be applicable not only to polyester but also to various fabrics.
Labels of supplementary figures from Spatial Architecture and Arrangement of Tumor-Infiltrating Lymphocytes for Predicting Likelihood of Recurrence in Early-Stage Non–Small Cell Lung Cancer (2023)

&lt;p&gt;Labels of supplementary figures&lt;/p&gt;
ChemInform Abstract: Synthesis, Physical Characterizations, and Langmuir Films of New Methanofullerenes. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A 121.4-dB DR Capacitively Coupled Chopper Class-D Audio Amplifier (2022)

This article presents a class-D amplifier (CDA) with high dynamic range (DR). To eliminate the typically dominant noise contribution of a resistive feedback network, the input and feedback signals are chopped and applied to a capacitive feedback network. However, this leads to high-voltage (HV) transients at the input of the loop filter, which, due to timing and impedance mismatch in the chopped feedback network, could degrade linearity and even overstress low-voltage (LV) core devices. Robust processing of the HV chopped feedback signal is guaranteed with chopper timing skew correction, chopper impedance matching, and deadbanding. The prototype, implemented in a 180-nm bipolar-CMOS-DMOS (BCD) process, achieves 121.4 dB of DR, 5.9 dB higher than state-of-the-art closed-loop CDAs, and 8- <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\mu \text{V}_{\mathrm {RMS}}$ </tex-math></inline-formula> output-referred noise (A-weighted). It also achieves a peak total harmonic distortion (THD) + N of −109.8 dB and a peak efficiency of 93%/88% while driving 15 W/26 W into an 8-/4- <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\Omega $ </tex-math></inline-formula> load.
Imaging Open-Cell Polyurethane Foam via Confocal Microscopy (1997)

Flexible polyurethane foam is based on a 3-dimensional cellular network. The mechanical properties of foam material depend upon cell structure and cell size distribution. In this work, we use laser confocal microscopy to image the foam cells and recover its 3-dimensional cellular network. Based on this technique we provide a statistical analysis and compare several foam samples. Confocal microscopic images are also used to visualize foam compression. Images for foam network structure under different mechanical compressions are also obtained. Limitations of confocal microscope are discussed and a new method - nuclear magnetic resonance imaging is proposed.
Voltage regulation of a series-stacked system of processors by differential power processing (2015)

Series-connected power delivery architecture have been shown to radically improve efficiencies for power delivery to servers and digital circuits. This paper investigates the element-to-element differential power processing topology. An average model for the series-stacked system with voltage regulating converters is proposed to aid in the closed-loop control design. Voltage regulation of the stack is simulated with a conventional 2-pole, 2-zero compensation scheme. Limitations regarding the number of cores that can be stacked in series and possible ways to overcome the limitations are also discussed. A modification to the element-to-element topology which improves transient response of the system is also suggested.
T Cells Regulate Peripheral Naive Mature B Cell Survival by Cell–Cell Contact Mediated through SLAMF6 and SAP (2017)

The control of lymphoid homeostasis is the result of a very fine balance between lymphocyte production, proliferation, and apoptosis. In this study, we focused on the role of T cells in the maintenance/survival of the mature naive peripheral B cell population. We show that naive B and T cells interact via the signaling lymphocyte activation molecule (SLAM) family receptor, SLAMF6. This interaction induces cell type-specific signals in both cell types, mediated by the SLAM-associated protein (SAP) family of adaptors. This signaling results in an upregulation of the expression of the cytokine migration inhibitory factor in the T cells and augmented expression of its receptor CD74 on the B cell counterparts, consequently enhancing B cell survival. Furthermore, in X-linked lymphoproliferative disease patients, SAP deficiency reduces CD74 expression, resulting in the perturbation of B cell maintenance from the naive stage. Thus, naive T cells regulate B cell survival in a SLAMF6- and SAP-dependent manner.
Methane to Acetic Acid over Cu-Exchanged Zeolites: Mechanistic Insights from a Site-Specific Carbonylation Reaction (2015)

The selective low temperature oxidation of methane is an attractive yet challenging pathway to convert abundant natural gas into value added chemicals. Copper-exchanged ZSM-5 and mordenite (MOR) zeolites have received attention due to their ability to oxidize methane into methanol using molecular oxygen. In this work, the conversion of methane into acetic acid is demonstrated using Cu-MOR by coupling oxidation with carbonylation reactions. The carbonylation reaction, known to occur predominantly in the 8-membered ring (8MR) pockets of MOR, is used as a site-specific probe to gain insight into important mechanistic differences existing between Cu-MOR and Cu-ZSM-5 during methane oxidation. For the tandem reaction sequence, Cu-MOR generated drastically higher amounts of acetic acid when compared to Cu-ZSM-5 (22 vs 4 μmol/g). Preferential titration with sodium showed a direct correlation between the number of acid sites in the 8MR pockets in MOR and acetic acid yield, indicating that methoxy species present in the MOR side pockets undergo carbonylation. Coupled spectroscopic and reactivity measurements were used to identify the genesis of the oxidation sites and to validate the migration of methoxy species from the oxidation site to the carbonylation site. Our results indicate that the Cu(II)-O-Cu(II) sites previously associated with methane oxidation in both Cu-MOR and Cu-ZSM-5 are oxidation active but carbonylation inactive. In turn, combined UV-vis and EPR spectroscopic studies showed that a novel Cu(2+) site is formed at Cu/Al <0.2 in MOR. These sites oxidize methane and promote the migration of the product to a Brønsted acid site in the 8MR to undergo carbonylation.
Origins, Development, Current Challenges and Future Directions with Activated Prothrombin Complex Concentrate for the Treatment of Patients with Congenital Haemophilia with Inhibitors (2020)

Congenital haemophilia A (HA) is caused by deficiency of coagulation factor VIII (FVIII) activity, leading to spontaneous or traumatic bleeding events. While FVIII replacement therapy can treat and prevent bleeds, approximately 30% of patients with severe HA develop inhibitor antibodies that render FVIII replacement therapy ineffective. The bypassing agents (BPAs), activated prothrombin complex concentrate (aPCC) and recombinant activated FVII, first approved in 1977 and 1996, respectively, act to generate thrombin independent of pathways that involve factors IX and VIII. Both may be used in patients with congenital haemophilia and inhibitors (PwHIs) for the treatment and prevention of acute bleeds and quickly became standard of care. However, individual patients respond differently to different agents. While both agents are approved for on-demand treatment and perioperative management for patients with congenital haemophilia with inhibitors, aPCC is currently the only BPA approved worldwide for prophylaxis in PwHI. Non-factor therapies (NFTs) have a mechanism of action distinct from BPAs and have reported higher efficacy rates as prophylactic regimens. Nonetheless, treatment challenges remain with NFTs, particularly regarding the potential for synergistic action on thrombin generation with concomitant use of other haemostatic agents, such as BPAs, for the treatment of breakthrough bleeds and in perioperative management. Concomitant use of NFTs with other haemostatic agents could increase the risk of adverse events such as thromboembolic events or thrombotic microangiopathy. This review focuses on the origins, development and on-going role of aPCC in the evolving treatment landscape in the management of PwHI.
ChemInform Abstract: A New Synthesis of Nitriles Enriched with 15N Isotope. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Overlay routing for fast video transfers in CDN (2017)

Content Delivery Networks (CDN) are witnessing the outburst of video streaming (e.g., personal live streaming or Video-on-Demand) where the video content, produced or accessed by mobile phones, must be quickly transferred from a point to another of the network. Whenever a user requests a video not directly available at the edge server, the CDN network must (1) identify the best location in the network where the content is stored, (2) set up a connection and (3) deliver the video as quickly as possible. For this reason, existing CDNs are adopting an overlay structure to reduce latency, leveraging the flexibility introduced by the Software Defined Networking (SDN) paradigm. In order to guarantee a satisfactory Quality of Experience (QoE) to users, the connection must respect several Quality of Service (QoS) constraints. In this paper, we focus on the sub-problem (2), by presenting an approach to efficiently compute and maintain paths in the overlay network. Our approach allows to speed up the transfer of video segments by finding minimum delay overlay paths under constraints on hop count, jitter, packet loss and relay node capacity. The proposed algorithm provides a near-optimal solution, while drastically reducing the execution time. We show on traces collected in a real CDN that our solution allows to maximize the number of fast video transfers.
Cognitive Brain Potentials and their Application (1990)

Computerised averaging methods have made it possible to extract and identify the electrical activity accompanying specific activities of the brain, including certain psychological processes, from the random background signals in electroencephalography (EEG). Event-related potentials (ERPs) and the way these change under various recording conditions are a powerful, non-invasive and relatively simple means of relating psychopathology to underlying physiology, and by comparing ERPs with imaging data it should be possible to compare electrical activity with changes in brain structure and blood flow in different disease states.
Ultrafast Time-Resolved Faraday Rotation in EuO Thin Films (2012)

We have investigated the ultrafast spin dynamics in EuO thin films by time-resolved Faraday rotation spectroscopy. The photoinduced magnetization is found to be increased in a transient manner, accompanied with subsequent demagnetization. The dynamical magnetization enhancement showed a maximum slightly below the Curie temperature with prolonged tails toward both lower and higher temperatures and dominates the demagnetization counterpart at 55 K. The magnetization enhancement component decays in ~1 ns. The realization of the transient collective ordering is attributable to the enhancement of the f-d exchange interaction.
GaN based high brightness LEDs and UV LEDs (2004)

This talk summarizes the important materials and device results in gallium nitride based light emitter technology. GaN has emerged as the most promising material for high brightness LEDs with colors ranging from UV to blue, green, and white. Recent progress on ultra-violet (UV) emitting LEDs using AlGaN single quantum wells indicates wavelengths as short as 292 nm are achievable. UV LEDs are of great interest for solid state white lighting due to the high conversion efficiencies of typical phosphors in the UV spectrum. This paper focuses on recent progress in improving the properties of UV LEDs.
Ética e orientação lacaniana (2012)

Artigo que conjuga a reflexão sobre a Ética da Psicanálise efetuada no Seminário da Antena do Campo Freudiano – Centro de Estudos de Psicanálise, em 2011-2012, com a apresentação feita em Bienos-Aires, por Jacques-Alain Miller, do tema - «A Desordem do real» - para o IX Congresso da Associação Mundial de Psicanálise.
ChemInform Abstract: IMIDAZOLATE COMPLEXES OF FERRIC PORPHYRINS (1977)

Abstract Elektronenspektroskopische Untersuchungen zeigen, daß der aus dem Chloro‐tetraphenylporphinato‐Fe(III)‐Komplex (I) dargestellte Bis‐[imidazol]‐Komplex (II) durch verschiedene Basen wie Tetrabutylammoniumhydroxid,K‐tert.‐butoxid oder K‐imidazolat am Imidazol unter Bildung der Produkte (III) und (IV) deprotoniert wird.
Outcomes and Quality of Life Improvement After Multilevel Spinal Fusion in Elderly Patients (2019)

In multilevel surgery in patients older than 70 years, complications are common, and on average 77% of patients attain some improvement, with 51% reaching an MCID. Physiological status is a stronger predictor of outcomes than chronological age.
Bioactive glass microspheres as reinforcement for improving the mechanical properties and biological performance of poly(ε‐caprolactone) polymer for bone tissue regeneration (2012)

This study examined the utility of sol-gel-derived bioactive glass microspheres (BGMs) as a reinforcement to improve the mechanical properties and biological performance of poly(ε-caprolactone) (PCL) polymer. All of the PCL-BGMs composites produced, with a variety of BGMs contents (10, 20, and 30 wt %), showed a uniform distribution of the BGMs in the PCL matrix, particularly owing to their spherical shape and small size. This led to a considerable increase in the elastic modulus from 93 ± 12 MPa to 635 ± 179 MPa with increasing BGMs content from 0 to 30 wt %. Furthermore, the addition of the BGMs to the PCL polymer significantly increased the hydrophilicity of the PCL-BGMs composites, which led to a higher water absorption and degradation rate. The PCL-BGMs composite with a BGMs content of 30 wt % showed vigorous growth of apatite crystals with a high aspect ratio on its surface after soaking in the simulated body fluid for 7 days, resulting in the creation of a porous carbonate hydroxyapatite layer.
Proteomic Analysis of a Response to Long-Chain Fatty Acid in Escherichia coli and Its Application (2007)

A long-chain fatty acid is a regulatory signal that modulates gene expression. In this study, proteomic studies that compared global translational differences between Escherichia coli cells grown in the presence of exogenous glucose and oleic acid were examined by two-dimensional gel electrophoresis (2-DE) and tandem mass spectrometry (LC-MS/MS). Of about 40 proteins showing altered expression levels with the presence of oleic acid, 10 including AldA, AceA, FadA, FadB, FadL, MalE, RbsB, Udp, Cdd and YccU were newly synthesized. Among them, the promoter of aldehyde dehydrogenase A (aldA promoter) was used for the production of a recombinant protein. Analysis of fluorescence intensities and confocal microscopic imaging revealed that aldA promoter is a very good promoter in that it is tightly controlled and highly expressed with active form compared with IPTG- inducible promoter. Thus the aldA promoter induced by oleic acid may be useful for achieving high-level expression of genes in E. coli.
Design, Fabrication, and Characterization of Package Embedded Solenoidal Magnetic Core Inductors for High-Efficiency System-In-Package Integrated Voltage Regulators (2019)

In this paper, we discuss the design, fabrication, and characterization of package embedded solenoidal inductor using a NiZn ferrite magnetic core material based on the novel fabrication process. The process relies on stencil printing of the magnetic core material along with the photolithography and copper electroplating of the inductor's traces. The electrical parameters of the fabricated inductors were extracted using a pi-equivalent circuit and showed an average dc resistance of 29 mΩ , an inductance of 26 nH, and an ac resistance of 2.62 Ω at 100 MHz, which represents the targeted switching frequency of the system-in-package integrated voltage regulator. The organic substrate parasitic effects were accounted for through the extraction of an average shunt capacitance of 1.2 pF and an average parasitic conductance of 0.12 mS at 100 MHz. The measured 10% saturation current of the inductor was 9.6 A. The electrical parameters of the fabricated inductors were modeled and showed a good agreement with the measured data.