gebhart/patrepeval huggingface dataset:
Rotordynamic Evaluation of Centrifugal Compressor Using Electromagnetic Exciter (2011)

Since heavier gases exert larger effects on rotordynamic stability, stability evaluation is important in developing or designing high-pressure compressors. To evaluate the rotor stability during operation, an excitation test using a magnetic bearing is the most practical method. In stability analysis, labyrinth seals can produce significant cross-coupling forces, which particularly reduce the damping ratio of the first forward mode. Therefore, forward modes should be distinguished from backward modes in the excitation test. One method that excites only the forward modes, not the backward modes (and vice versa), is the use of a rotating excitation. In this method, the force is simultaneously applied to two axes to excite the rotor in circular orbits. Two trigonometric functions, i.e., cosine and sine functions, are used to generate this rotation force. Another method is the use of a unidirectional excitation and a mathematical operation to distinguish the forward whirl from the backward whirl. In this method, a directional frequency response function that separates the two modes in the frequency domain is obtained from four frequency response functions by using a complex number expression for the rotor motion. In this study, the latter method was employed to evaluate the rotor stability of a high-pressure compressor. To obtain the frequencies and damping ratios of the eigenvalues, the curve fitting based on system identification methods, such as the prediction error method, was introduced for the derived frequency response functions. Firstly, these methods were applied to a base evaluation under a low-pressure gas operation, in which the stability mainly depends on the bearing property. Using the obtained results, the bearing coefficients were estimated. Next, the same methods were applied to stability evaluations under high-pressure gas operations. The destabilizing forces were also estimated from the test results and compared with the calculation results.
Large deformation mechanical testing of biological membranes using speckle interferometry in transmission II: Finite element modeling (1997)

In holography and speckle interferometry the measurement range is generally limited by the greatest number of fringes that can be resolved in a single image. As a result these techniques have been generally confined to small displacement measurement applications. In the case of out-of-plane measurements one can overcome this limitation by simply adding incremental measurements at individual detector pixels. In the case of in-plane measurements, however, summing incremental measurements is not a straightforward procedure since the interference pattern moves laterally across the detector as the material deforms. We describe a modeling technique based on finite elements which solves this problem. In combination with a full field method such as holography or speckle interferometry, it provides a very sensitive measurement technique with dense spatial sampling and large dynamic range. Experimental results of speckle interferometry operating in transmission to measure in-plane displacements of biological membranes are presented, where total material displacements are of the order of millimeters. The results also demonstrate how the finite strain tensor is calculated analytically from the data at any point on the material.
Spectre du signal de backscattering des tags RFID UHF passifs (2013)

National audience
New Equipment Designs Enable Swellable Technology in Cementless Completions (2008)

Abstract In the oil and gas industry, it is a common practice to install production casing through producing formations, with cement providing the primary inter-zonal isolation in the annulus. However, inadequate displacement efficiencies, fluid contamination, and loss circulation intervals sometimes limit the ability of a cementing operation to provide zonal isolation sufficient to prevent annular communication over the life of the well. Formation damage caused by cementing operations can also adversely affect life-of-the-well production capabilities, thereby adversely affecting the economics of the well. New completion technologies using swellable elastomers can offer an alternative to cementing operations performed over producing formations. However, conventional floating equipment has limited the application of swellable elastomers in some completion operations. For example, in noncemented completions where swellable elastomers provide the only annular barrier, a mechanical seal having a service life equal to the life of the well under downhole conditions is required at the toe of the production casing. This paper describes the benefits of swellable elastomers used to provide life-of-the-well zonal isolation. Additionally, the paper recounts a problem job in which improperly selected check valves were used and new check valves specifically designed for noncemented completions were successfully introduced. Lastly, this paper provides details about equipment designed for a south Texas well that will incorporate SEPs, float equipment, and a combination wiper plug designed specifically for a noncemented completion to be performed in late 2007 or early 2008.
Work Practice and Technology (2011)

During the decade from 1989 to 1999, workplace research at PARC was based in the Work Practice and Technology research area. In anticipation of the group's disbanding in 2000, its members organized a symposium under the heading “Work Practice and Technology: The next twenty years of research.” Over one hundred participants attended from North America, Western Europe, Scandinavia, Japan, and Australia. The symposium consisted of one day of panels at Xerox PARC, followed by two days of working groups and celebrations at Half Moon Bay, California.
ChemInform Abstract: Inhibitory Effects of 1‐Deazaadenosine Analogues on HIV Replication and Adenosine Deaminase. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Real-Time Imaging System for the OpenPET (2011)

The OpenPET and its real-time imaging capability have great potential for real-time tumor tracking in medical procedures such as biopsy and radiation therapy. For the real-time imaging system, we intend to use the one-pass list-mode dynamic row-action maximum likelihood algorithm (DRAMA) and implement it using general-purpose computing on graphics processing units (GPGPU) techniques. However, it is difficult to make consistent reconstructions in real-time because the amount of list-mode data acquired in PET scans may be large depending on the level of radioactivity, and the reconstruction speed depends on the amount of the list-mode data. In this study, we developed a system to control the data used in the reconstruction step while retaining quantitative performance. In the proposed system, the data transfer control system limits the event counts to be used in the reconstruction step according to the reconstruction speed, and the reconstructed images are properly intensified by using the ratio of the used counts to the total counts. We implemented the system on a small OpenPET prototype system and evaluated the performance in terms of the real-time tracking ability by displaying reconstructed images in which the intensity was compensated. The intensity of the displayed images correlated properly with the original count rate and a frame rate of 2 frames per second was achieved with average delay time of 2.1 s.
Bacterial flagellar capping proteins adopt diverse oligomeric states (2016)

Flagella are crucial for bacterial motility and pathogenesis. The flagellar capping protein (FliD) regulates filament assembly by chaperoning and sorting flagellin (FliC) proteins after they traverse the hollow filament and exit the growing flagellum tip. In the absence of FliD, flagella are not formed, resulting in impaired motility and infectivity. Here, we report the 2.2 Å resolution X-ray crystal structure of FliD from <i>Pseudomonas aeruginosa</i>, the first high-resolution structure of any FliD protein from any bacterium. Using this evidence in combination with a multitude of biophysical and functional analyses, we find that <i>Pseudomonas</i> FliD exhibits unexpected structural similarity to other flagellar proteins at the domain level, adopts a unique hexameric oligomeric state, and depends on flexible determinants for oligomerization. Considering that the flagellin filaments on which FliD oligomers are affixed vary in protofilament number between bacteria, our results suggest that FliD oligomer stoichiometries vary across bacteria to complement their filament assemblies.
P1‐143: Specific in vivo detection of amyloid plaques in transgenic mice using bifunctional USPIO nanoparticles (2012)

Amyloid plaques are a key pathological hallmark of Alzheimer's disease (AD). Their visualization is important for the diagnosis of AD, monitoring disease progression and evaluation of the efficacy of therapeutic interventions. We were the first group to use ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles coupled to an amyloid targeting peptide to visualize amyloid plaques. USPIO's have been widely used in animal and human imaging, and have been found to be very safe. However, our approach, so far, has required intra-carotid or intra-femoral injection, with mannitol to break the blood brain barrier (BBB). In the current study we sought to develop and test non-toxic, bifunctional USPIO particles which could be introduced via the femoral vein, without mannitol. 13 to 18 month old APP/PS1 transgenic mice and age-matched wild-type (C57Bl/6J) control mice were used. The USPIO nanoparticles were linked to Aβ1–42 (targeting to amyloid plaques) and polyethyleneglycol (PEG, to increase BBB permeability), using EDC/NHS coupling methods. The potential neurotoxicity of USPIO-PEG-Aβ42 was assessed in N2a cells using a MTS Assay. MRI scans were performed on a 7T micro-MRI system consisting of a 7-Telsa 200-mm horizontal bore magnet. All mice were scanned 6-hrs after iv injection (0.2 mmol Fe/kg body weight) of the USPIO-PEG-Aβ42. Ex vivo imaging of mouse brains was also performed. Serial coronal sections were subject to anti-Aβ immunohistochemistry and Perl staining to identify the USPIO. Our non-toxic, non-invasive m MRI method has great potential for the longitudinal assessment of amyloid burden.
Reliability issues in deep deep sub-micron technologies: time-dependent variability and its impact on embedded system design (2007)

In the future sub 45 nm regime, uncertainties would be way too high to be handled with existing worst-case design techniques without incurring significant penalties in terms of area/delay/energy. As a result, reliability becomes a great threat to the design of reliable complex digital systems-on-chip (SoC) implementations. This will require the development of novel reliability models at all three levels, namely device, circuit and system level. They should be capable of capturing the impact of the application functionality on the system as well as new design paradigms for embedded system design in order to build reliable systems using technology which will be largely unpredictable in nature. A shift toward technology-aware design solutions will be required to keep designing successful systems in future aggressively scaled technologies.
Use of Luminescent CdSe-ZnS Nanocrystal Bioconjugates in Quantum Dot-Based Nanosensors (2002)

Biomolecules labeled with luminescent colloidal semiconductor quantum dots (QDs) have potential for use in numerous applications, including fluoro-immunoassays and biological imaging. QD labels exhibit size-tunable narrow-band luminescent emission and high resistance to photodegradation. They also exhibit efficient Förster energy transfer between neighboring QDs of different sizes and their emission is readily quenched by bound fluorescent dyes. In this paper, we describe preliminary results aimed at defining conditions for the design and preparation of nanoscale QD-bioconjugate sensors based on fluorescence quenching. We envision building sensor assemblies that employ quantum dots linked with dye-labeled biological receptors that utilize donor–acceptor energy transfer between QDs and receptors for conducting recognition-based assays. In particular, we report the effects of varying the concentration of energy acceptors bound to nanocrystal surfaces under both soluble and solid phase conditions on quenching phenomena.
Angle multiplexed metasurfaces (2023)

A metasurface is defined by an array of scattering elements having a U shape, where the geometrical dimensions determining the U shape are determined according to the different phase profiles that the metasurface is meant to generate in response to an incident electromagnetic wave. The metasurface, therefore, generates different phase shifts as a function of the incident electromagnetic wave.
On-Ground UWB Antenna Mounted on External Wind Turbine Blade Surface for Deflection Tracking (2019)

In this paper, a low-profile UWB antenna is proposed which is mountable on the external surface of the blade. The antenna covers the UWB band of 3.1-4.9 GHz with the endfire radiation pattern. Different locations of the antenna on the external surface are investigated. Trailing edge location is a good alternative to the leading edge when placing the UWB antenna externally. Full-blade measurements are carried out to study the UWB pulse quality. It is found that in the applications, the root antenna over the downwind surface and the external tip antenna on the trailing edge should be utilized in order to realize high-quality UWB pluses in different deflections and satisfy the application requirement of air dynamics.
T lymphocytes are not required for the development of fatty degeneration after rotator cuff tear (2014)

The extent of degenerative changes in nude rats was similar to what was observed in T-cell competent rats. T cells may not play an important role in regulating muscle degeneration following chronic muscle unloading. The general similarities between nude and T-cell competent rats suggest the nude rat is likely an appropriate preclinical model for the study of xenografts that have the potential to enhance the treatment of chronically torn rotator cuff muscles. Cite this article: Bone Joint Res 2014;3:262-72.
A Discussion of Reversible and Irreversible Sorption for Sr, Cs, Np, and Pu (2010)

Here we discuss the possibility that fission product and actinide sorption is reversible when thermodynamic and kinetic factors are accounted for in predictive models. We do this by reviewing the sorption behavior of Sr, Cs, Np, and Pu, and by reviewing our ability to model their sorption behavior.
Validation of a multi-marker test that predicts recurrence in patients diagnosed with ductal carcinoma in situ (DCIS) treated with breast-conserving surgery (BCS) (2015)

Validation of a multi-marker test that predicts recurrence in patients diagnosed with ductal carcinoma in situ (DCIS) treated with breast-conserving surgery (BCS)
Towards Reduced-State Service Chaining with Source Routing (2018)

The widespread adoption of Network Function Virtualization (NFV) poses significant dataplane scalability limitations in datacenters (DC), as switches will be required to maintain a large amount of forwarding state for service chaining. This problem is exacerbated by the small Forwarding Information Base (FIB) of commodity switches, which are typically deployed in NFV infrastructures.To mitigate this problem, we present a routing fabric that combines source routing with pathlet switching in order to (i) achieve state reduction and (ii) provide support for longer paths, hence, meeting the increased hop-count requirement of service chains. Coupling the proposed source routing fabric with a service chain embedding method, we achieve significant gains in terms of FIB consumption, request acceptance, and revenue generation.
ORAL POSTER 9: Delivery Mode Is a major Determinant of Stress Urinary Incontinence in Childbearing Women: Analysis of 542 Identical Twins (2005)

P. S and Evanston Continence Center, Evanston, IL; Northwestern University, Feinberg School of Medicine, Chicago, IL Disclosure – Speakers Bureau: P.K. Sand, Alza/Ortho-McNeil, Watson, American Medical Systems; Advisory Board: P.K. Sand, Alza/Ortho-McNeil, Watson, American Medical Systems, Indevus, Yamanouchi, Roche, Pfizer, Bioform, Lilly, Boeringer-Ingelheim, Mentor, Novasys; Grant/Research: P.K. Sand, Alza/Ortho-McNeil, Watson, American Medical Systems, Indevus, Yamanouchi, Roche, Pfizer, Bioform, Lilly, Boeringer-Ingelheim, Mentor, Novasys.
Short-Circuit Analysis of the UNIFLEX-PM Using Stationary and Natural Reference Frame Control (2009)

In order to allow a sustainable energy future based on a large share of Distributed Generation (DG), there is a clear need to prepare the European electricity system for the large-scale integration of both renewable and other distributed energy sources. Advanced power electronic converters for DG will be needed to control the power flow and to ensure proper and secure operation of this future grid with an increased level of the renewable power. These power converters must be able to provide intelligent power management as well as ancillary services. This paper presents a short-circuit analysis of a multi-level H-bridge power converter for Universal and Flexible Power Management (UNIFLEX-PM) in Future Electricity Network. The analysis is made for two different control strategies, namely the stationary and the natural reference frame control. Selected simulation results are presented in order to compare the behavior of the two control strategies under various grid short-circuits.
Ordered Carbon Nanotubes for Optical Power Limiting Devices (2011)

The electrospinning (ES) process was used to fabricate composite nanofibers (NFs) of poly(methyl methacrylate), PMMA, with embedded multiwalled carbon nanotubes (MWNTs) from a solution of PMMA in N,N-dimethylformamide (DMF) with homogenously dispersed MWNTs. Using both the sinklike and the elongation flows in the electrospinning process, we aligned the carbon nanotubes (CNTs) along the fiber axis. The NFs were subsequently deposited in an aligned manner on a glass surface using the electrostatic lens created by the edge of a rotating wheel collector. Semitransparent optical power limiter (OPL) films (~50% transmittance) were fabricated using an optically compatible polymeric resin infiltrated into the collected NFs. These comprised oriented NFs with different carbon nanotube loadings and film thicknesses. The OPLs exhibited high limiting abilities, with a limiting threshold of 1.5 J/cm(2) at about 50% linear transmittance. Some degree of polarization was also achieved, but significantly lower than expected because of the NF orientation.
Control of Camless Intake Process—Part II1 (1998)

A model-based control scheme is designed to regulate the cylinder air charge of a camless multicylinder engine for unthrottled operation. The controller consists of a feedforward and an adaptive feedback scheme based on a control-oriented model of the breathing process of an engine equipped with electro-hydraulic springless valvetrain. The nonlinear control scheme is designed to achieve cylinder-to-cylinder balancing, fast cycle-to-cycle response, and minimization of pumping losses. The algorithm uses conventional sensor measurements of intake manifold pressure and mass air flow to the intake manifold, and intake valve duration measurement. Closed-loop simulation results are shown for a four-cylinder engine. [S0022-0434(00)03001-X]
Current topics on precursors to pancreatic cancer. (2006)

Prognosis of invasive pancreatic ductal adenocarcinoma is bleak and the vast majority of patients with pancreatic cancer die of their disease. The detection and treatment of the non-invasive precursor lesions of pancreatic cancer offer the opportunity to cure this devastating disease and therefore great efforts are being made to identify the precursors to pancreatic cancer. Several distinct precursor lesions have been identified. Mucinous cystic neoplasms (MCNs), intraductal papillary mucinous neoplasms (IPMNs), and pancreatic intraepithelial neoplasias (PanINs) all harbor varying degrees of dysplasia and stepwise accumulation of genetic alterations, suggesting progression of these lesions from benign toward malignant neoplasms. MCNs have a characteristic ovarian-type stroma. About one-third of MCNs are associated with invasive carcinoma of ductal phenotype. IPMNs are recently established clinical entity with characteristic features of mucin hypersecretion and duct dilatation. Some IPMNs are associated with invasive carcinoma and IPMNs are recognized precursors to pancreatic cancer. PanINs are microscopic proliferative lesions arising from any parts of the pancreatic duct system. Low grade PanINs are commonly found in pancreatic ducts of elder individuals, while high grade PanINs, previously called carcinoma in situ/severe ductal dysplasia, may eventually give rise to invasive pancreatic cancer. Appropriate clinical managements are requisite for patients with MCNs, IPMNs and PanINs. Further investigation of these precursor lesions is expected to reduce the mortality from pancreatic cancer.
Targeted Derivation of Organotypic Glucose- and GLP-1-Responsive β Cells Prior to Transplantation into Diabetic Recipients (2019)

Generation of functional β cells from pluripotent sources would accelerate diagnostic and therapeutic applications for diabetes research and therapy. However, it has been challenging to generate competent β cells with dynamic insulin-secretory capacity to glucose and incretin stimulations. We introduced transcription factors, critical for β-cell development and function, in differentiating human induced pluripotent stem cells (PSCs) and assessed the impact on the functionality of derived β-cell (psBC) progeny. A perifusion system revealed stepwise transduction of the PDX1, NEUROG3, and MAFA triad (PNM) enabled in vitro generation of psBCs with glucose and GLP-1 responsiveness within 3 weeks. PNM transduction upregulated genes associated with glucose sensing, insulin secretion, and β-cell maturation. In recipient diabetic mice, PNM-transduced psBCs showed glucose-responsive insulin secretion as early as 1 week post transplantation. Thus, enhanced pre-emptive β-cell specification of PSCs by PNM drives generation of glucose- and incretin-responsive psBCs in vitro, offering a competent tissue-primed biotherapy.