gebhart/patrepeval huggingface dataset:
Characterization of electrochemically active bacteria utilizing a high‐throughput voltage‐based screening assay (2008)

Metal reduction assays are traditionally used to select and characterize electrochemically active bacteria (EAB) for use in microbial fuel cells (MFCs). However, correlating the ability of a microbe to generate current from an MFC to the reduction of metal oxides has not been definitively established in the literature. As these metal reduction assays may not be generally reliable, here we describe a four- to nine-well prototype high throughput voltage-based screening assay (VBSA) designed using MFC engineering principles and a universal cathode. Bacterial growth curves for Shewanella oneidensis strains DSP10 and MR-1 were generated directly from changes in open circuit voltage and current with five percent deviation calculated between each well. These growth curves exhibited a strong correlation with literature doubling times for Shewanella indicating that the VBSA can be used to monitor distinct fundamental properties of EAB life cycles. In addition, eight different organic electron donors (acetate, lactate, citrate, fructose, glucose, sucrose, soluble starch, and agar) were tested with S. oneidensis MR-1 in anode chambers exposed to air. Under oxygen exposure, we found that current was generated in direct response to additions of acetate, lactate, and glucose.
Raman and photoluminescence spectroscopy investigations of ZnO nanostructures (2007)

We discuss Raman and photoluminescence (PL) studies of ZnO in solid, thin film and nanowire samples. Resonant laser excitations ranging from near-infrared to ultraviolet are used in order to observe and analyse ZnO nanostructures. The changes of optical emission and electronic bandgap response to the vibration modes are studied simultaneously by PL and Raman spectroscopy. Both Raman and PL spectroscopy analyses of nanostructure, electronic bandgaps and photo-emission demonstrate that nanostructure geometry, including its aspect ratio, and phonon–electron interactions play important roles in polar semiconductor structures such as ZnO.
Reliability enhancement of 1Xnm TLC for cold flash and millennium memories (2015)

Endurance and retention are measured in 1Xnm Triple Level Cell (TLC) NAND and the flexible nLC scheme (flex-nLC) is proposed to improve reliability. This method enables the use of lowest-cost TLC NAND as is, in long term storage applications such as cold flash and digital archive: millennium memory, which have 20 and 1000 years retention, respectively.
Digital signal processing: Enabling a revolution in optical networking (2014)

Over the last decade, digital signal processing has revolutionized the design and operation of optical networks. In this tutorial we chart this revolution, discussing the key algorithms and technologies before speculating on future research directions. © 2014 Engineers Australia.
Upgrade of the Fast Beam Intensity Measurement System for the CERN PS Complex (2014)

The CERN Proton Synchrotron complex (CPS) has been operational for over 50 years. During this time the Fast Beam Current Transformers (FBCTs) have only been repaired when they ceased to function, or individually modified to cope with new requests. This strategy resulted in a large variation of designs, making their maintenance difficult and limiting the precision with which comparisons could be made between transformers for the measurement of beam intensity transmission. During the first long shutdown of the CERN LHC and its injectors (LS1) these systems have undergone a major consolidation, with detectors and acquisition electronics upgraded to provide a uniform measurement system throughout the PS complex. This paper discusses the solutions used and analyses the first beam measurement results.
Active imaging at DARPA (2005)

Active systems, because they provide their own illumination, are capable of operating 24 hours a day and are not dependent upon the angle of the sun. Unlike passive systems, they can provide three-dimensional imaging. DARPA is currently developing systems, technologies, and signal processing to pioneer new or improve existing capabilities that employ active imaging capabilities. These involve both radar and ladar, ranging from a few MHz for foliage penetration to near-visible IR to achieve ultra-high resolution at long range. These capabilities would improve Battlefield Awareness (BA) and provide persistent Intelligence, Surveillance, and Reconnaissance (ISR) to perform target detection, recognition, and identification. This paper discusses two different approaches to active optical imaging. One is a coherent approach that uses synthetic aperture techniques with infrared laser radar, and another approach uses only the intensity of the speckle pattern in the aperture plane. Both are capable of producing ultra-high resolution at long range.
The plasminogen activator system: involvement in central nervous system inflammation and a potential site for therapeutic intervention (2013)

Cumulatively, our results suggest a role for uPA and uPAR in EAE pathogenesis, as exacerbation of disease was seen in their absence. Furthermore, the successful amelioration of EAE by PAI-1 treatment suggests that the PA system can be considered a potential site for therapeutic intervention in the treatment of neuroimmune diseases.
Specification completion for IOCO (2011)

The paper is devoted to the ioco relation, which determines conformance of an implementation to the specification. Problems related to nonreflexivity of the ioco relation, presence of nonconformal traces (which are lacking in any conformal implementation) in the specification, lack of the ioco preservation upon composition (composition of implementations conformal to their specifications may be not conformal to the composition of these specifications), and “false” errors when testing in a context are considered. To solve these problems, an algorithm of specification completion preserving ioco is proposed (the class of conformal implementations is preserved). The above-specified problems are lacking in the class of completed specifications.
In vitro RBE-LET dependence for multiple particle types (2011)

All RBE-LET data points demonstrate surprising agreement within the general error band formed by the numerous data points, and display the expected RBE peak at around 100-200 keV/μm. For all three cell lines, the influence of varying the particle type on the RBE was far from obvious, compared to the general experimental noise. Therefore, a dependence of particle type cannot be concluded, and LET alone in fact does seem to be an adequate parameter for describing RBE at 10% survival.
Identification of expression quantitative trait loci by the interaction analysis using genetic algorithm (2007)

Many genes with major effects on quantitative traits have been reported to interact with other genes. However, finding a group of interacting genes from thousands of SNPs is challenging. Hence, an efficient and robust algorithm is needed. The genetic algorithm (GA) is useful in searching for the optimal solution from a very large searchable space. In this study, we show that genome-wide interaction analysis using GA and a statistical interaction model can provide a practical method to detect biologically interacting loci. We focus our search on transcriptional regulators by analyzing gene x gene interactions for cancer-related genes. The expression values of three cancer-related genes were selected from the expression data of the Genetic Analysis Workshop 15 Problem 1 data set. We implemented a GA to identify the expression quantitative trait loci that are significantly associated with expression levels of the cancer-related genes. The time complexity of the GA was compared with that of an exhaustive search algorithm. As a result, our GA, which included heuristic methods, such as archive, elitism, and local search, has greatly reduced computational time in a genome-wide search for gene x gene interactions. In general, the GA took one-fifth the computation time of an exhaustive search for the most significant pair of single-nucleotide polymorphisms.
What Is Measured When Measuring Acidity in Zeolites with Probe Molecules? (2019)

Based on theoretical calculations of CO, NH<sub>3</sub>, and pyridine adsorption at different sites in MOR and MFI zeolites, we analyze how confinement effects influence the measurement of acidity based on the interaction of probe molecules with Brönsted acid sites. Weak bases, such as CO, form neutral ZH-CO adducts with a linear configuration that can be distorted by spatial restrictions associated with the dimensions of the pore, leading to weaker interaction, but can also be stabilized by dispersion forces if a tighter fitting with the channel void is allowed. Strong bases such as NH<sub>3</sub> and pyridine are readily protonated on Brönsted acid sites, and the experimentally determined adsorption enthalpies include not only the thermochemistry associated with the proton transfer process itself, but also the stabilization of the Z<sup>-</sup>-BH<sup>+</sup> ion pair formed upon protonation by multiple interactions with the surrounding framework oxygen atoms, leading in some cases to a heterogeneity of acidities within the same zeolite structure.
Development of a novel, quantitative protein microarray platform for the multiplexed serological analysis of autoantibodies to cancer-testis antigens (2014)

The cancer-testis antigens are a group of unrelated proteins aberrantly expressed in various cancers in adult somatic tissues. This aberrant expression can trigger spontaneous immune responses, a phenomenon exploited for the development of disease markers and therapeutic vaccines. However, expression levels often vary amongst patients presenting the same cancer type, and these antigens are therefore unlikely to be individually viable as diagnostic or prognostic markers. Nevertheless, patterns of antigen expression may provide correlates of specific cancer types and disease progression. Herein, we describe the development of a novel, readily customizable cancer-testis antigen microarray platform together with robust bioinformatics tools, with which to quantify anti-cancer testis antigen autoantibody profiles in patient sera. By exploiting the high affinity between autoantibodies and tumor antigens, we achieved linearity of response and an autoantibody quantitation limit in the pg/mL range-equating to a million-fold serum dilution. By using oriented attachment of folded, recombinant antigens and a polyethylene glycol microarray surface coating, we attained minimal non-specific antibody binding. Unlike other proteomics methods, which typically use lower affinity interactions between monoclonal antibodies and tumor antigens for detection, the high sensitivity and specificity realized using our autoantibody-based approach may facilitate the development of better cancer biomarkers, as well as potentially enabling pre-symptomatic diagnosis. We illustrated the usage of our platform by monitoring the response of a melanoma patient cohort to an experimental therapeutic NY-ESO-1-based cancer vaccine; inter alia, we found evidence of determinant spreading in individual patients, as well as differential CT antigen expression and epitope usage.
Assessing hypoxia in animal tumor models based on pharmocokinetic analysis of dynamic FAZA PET (2010)

High tumor-to-reference tissue ratios and a strong linear correlation (R∼0.7 to 0.95) between density of hypoxic cells and FAZA concentration was observed three hours after tracer administration, suggesting that late time PET images provides an accurate measure of hypoxia against which kinetic model estimates can be validated. Tumor TACs varied widely (ranging from distinctly wash-out to accumulative type) among tumor types although pimonidazole-stainings revealed extensive hypoxia in all models. Kinetic analysis of tumor sub-volumes showed that k(3) correlated poorly with late time FAZA retention regionally in two of the three tumor models. The influx rate constant K(i) displayed far less variability and correlated strongly with late time FAZA retention (hypoxia) in two of three tumor models, whereas a non-consistent relationship was observed in the last tumor model. Our study demonstrates the potential usefulness of dynamic PET, but also that a simple two-compartment model may be inappropriate in some tumor models.
Lithium beam characterization of cylindrical PBFA II hohlraum experiments (1995)

Summary form only given, as follows. Sandia National Laboratories is actively engaged in exploring indirect-drive inertial confinement fusion on the Particle Beam Fusion Accelerator (PBFA II) with pulsed-power accelerated lithium ions as the driver. Experiments utilizing cylindrical hohlraum targets were conducted in 1994. Using the incoming ion beam-induced line radiation from titanium wires surrounding these hohlraums, beam profiles during these experiments have been measured and characterized, these data, their comparison/cross-correlation with particle-based beam diagnostics, and an analysis of the beam parameters that most significantly influence target temperature are presented.
Oxygen and Silicon Ion Particles Induce Neoplastic Transformation in Human Colonic Epithelial Cells (2014)

ABSTRACT High charge (Z) and energy (E) (HZE) particles in deep space have significantly contributed to the biological effects of space radiation, although they only account for less than 1% of the galactic cosmic rays (GCR) particle fluxes. Previously we have shown that combined radiation exposure of 2-Gy proton ( 1 H) followed by 0.5-Gy iron ( 56 Fe) ion particles increase transformation in human colonic epithelial cells (HCEC CT7). The present study was undertaken to characterize if additional HZE ions, such as oxygen ( 16 O) and silicon ( 28 Si) particles, also result in increased cell transformation. HCEC CT7 cells irradiated with 1-Gy 16 O (250 MeV/nucleon), followed 24 hours later by 1-Gy 28 Si particle (300 MeV/nucleon), showed an increase in proliferation, anchorage-independent growth, migration, and invasion abilities compared to unirradiated controls. In addition, we found that the β-catenin pathway was activated and that subsets of DNA repair genes were under-expressed in these transformed cells. Pretreatment with the radioprotector, CDDO-Me, 18 hours before and during irradiation prevented the HZE-induced transformation. These results can be interpreted to suggest that the mixed radiation exposure of 16 O followed by 28 Si has carcinogenic potential. Importantly, this transformation can be protected by CDDO-Me pre-treatment.
Pluronic F‐127: An Efficient Delivery Vehicle for 3‐(1'‐hexyloxy)ethyl‐3‐devinylpyropheophorbide‐a (HPPH or Photochlor) (2019)

To determine the impact of delivery vehicles in photosensitizing efficacy of HPPH, a hydrophobic photosensitizer was dissolved in various formulations: 1% Tween 80/5% dextrose, Pluronic P-123 and Pluronic F-127 in 0.5%, 1% and 2% phosphate buffer solutions (PBS). HPPH was also conjugated to Pluronic F-127, and the resulting conjugate (PL-20) was formulated in PBS. Among the different delivery vehicles, only Pluronic P-123 displayed significant vehicle cytotoxicity, whereas Pluronic F127 was nontoxic. Compared to PL-20, HPPH formulated in Tween80 and Pluronic F-127 showed higher cell-uptake, but lower long-term retention in Colon26 cell compared to PL-20. The higher retention of PL-20 was similarly observed during in vivo uptake with BALB/c mice baring Ct26 tumors. In contrast to the in vitro uptake experiments, PL-20 showed slightly higher uptake compared to HPPH formulated in Tween or Pluronic-F127. A significant difference in pharmacokinetic profile was also observed between the HPPH-Pluronic formulation and PL-20. Under similar in vivo treatment parameters (drug dose 0.47 µmol kg<sup>-1</sup> , light dose: 135 J cm<sup>-2</sup> at 24 h post-injection of PS), HPPH formulated either in Tween or Pluronic F-127 formulation showed similar in vivo PDT efficacy (20-30% tumor cure on day 60), whereas PL-20 showed 40% tumor cure (day 60).
Real-time 100-Gb/s POLMUX RZ-DQPSK Transmission over Uncompensated 500 km of SSMF by Optical Phase Conjugation (2009)

We present an effective solution for the upgrade of a highly dispersive link to POLMUX RZ-DQPSK 100-Gb/s transmission. Dispersion compensation is obtained by properly inserting a single polarization-insensitive phase-conjugation device along the link.
Photochemical reactivity of trans-diacidotetracyanocobaltate(III) complexes (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotochemical reactivity of trans-diacidotetracyanocobaltate(III) complexesMark Wrighton, Harry B. Gray, George S. Hammond, and Vincent MiskowskiCite this: Inorg. Chem. 1973, 12, 4, 740–743Publication Date (Print):April 1, 1973Publication History Published online1 May 2002Published inissue 1 April 1973https://pubs.acs.org/doi/10.1021/ic50122a006https://doi.org/10.1021/ic50122a006research-articleACS PublicationsRequest reuse permissionsArticle Views25Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Die-bonding performance and mechanism based on the sintering of micro Ag paste for high power devices (2016)

Commercially available micron-sized Ag flake particles and submicron-sized Ag particles were used to make Ag paste. The Ag paste was used to connect Si dies to Ni-Ag plated Cu substrates to achieve die-bonding joint for high temperature application. The contact between die and Ag paste was affected by the loading pressure, and was realized with only 0.2 MPa pressure. And the shear strength depended on the bonding pressure and increased over 20 MPa with only 0.2 MPa pressure. The high shear strength achieved at low bonding pressure contributed to the tight contact between die and paste, and optimized bonding pressure.
<title>Wavelet transforms in a JPEG-like image coder</title> (1994)

The discrete wavelet transform is incorporated into the JPEG baseline coder for image coding. The discrete cosine transform is replaced by an association of two-channel filter banks connected hierarchically. The scanning and quantization schemes are devised and the entropy coder used is exactly the same as used in JPEG. The result is a still image coder that outperforms JPEG while retaining its simplicity and most of its existing building blocks. Objective results and reconstructed images are presented.
On the linear compensation of hysteresis (2002)

Compensation for hysteresis often relies on a precise system model. This makes controller design complicated and time consuming. In this paper, the Preisach hysteresis model is interpreted in terms of phase shift. This leads to a simple linear compensator design methodology. The closed-loop connection of a compensator that we call a phaser with a nonlinear system with hysteresis is shown to produce an almost linear response in a given operating range. The present method is advantageous for its simplicity and robustness and requires the identification of only one parameter. This result is experimentally applied to the control of a piezoceramic actuator.
Efficient Preparation of ((3‐Chloro‐2‐fluorophenyl)‐ [7‐methoxy‐8‐ (3‐morpholin‐4‐yl‐propoxy)‐10,11‐dihydro‐5‐oxa‐2,4,11‐triazadibenzo (a,d)cyclohepten‐1‐yl]amine) for in vivo Study. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Elliptic curve DSA (ECSDA): an enhanced DSA (1998)

The Elliptic Curve Digital Signature Algorithm (ECDSA) is the elliptic curve analogue of the Digital Signature Algorithm (DSA), and is under consideration for standardization by the ANSI X9 committee. Unlike the normal discrete logarithm problem and the integer factorization problem, the elliptic curve discrete logarithm problem has no subexponential-time algorithm. For this reason, the strength-perkey-bit is substantially greater in an algorithm that uses elliptic curves. In this paper, we compare the draft ANSI X9.62 ECDSA to the ANSI X9.30 DSA, the latter of which is identical to FIPS 186 DSS.
Aging and cancer resistance in lymphoid progenitors are linked processes conferred by p16 Ink4a and Arf (2008)

Lymphoid progenitors exhibit severe growth defects during aging while myelopoiesis is relatively unperturbed. These effects are due in part to the preferential expression of p16(Ink4a) and Arf in aged lymphoid progenitors. Their increased expression contributes to reduced growth and survival of lymphoid progenitors and makes them refractory to malignant transformation. Down-regulation of p16(Ink4a) and Arf in aged lymphoid progenitors reverted the senescent phenotype and restored susceptibility to transformation. These data provide a molecular explanation for the preferential effects of aging on lymphopoiesis, suggest that inhibiting p16(Ink4a) and Arf expression can rejuvenate B lymphopoiesis, and link aging and cancer resistance.
1329: Observation of Enhancing Renal Masses: A Metaanalysis of Worldwide Data (2005)

You have accessJournal of UrologyPodium, Tuesday, May 24, 2005, 1:00 - 3:00 pm1 Apr 20051329: Observation of Enhancing Renal Masses: A Metaanalysis of Worldwide Data Sam N. Chawla, Paul L. Crispen, Alexandra L. Hanlon, David Y.T. Chen, Richard E. Greenberg, and Robert G. Uzzo Sam N. ChawlaSam N. Chawla More articles by this author , Paul L. CrispenPaul L. Crispen More articles by this author , Alexandra L. HanlonAlexandra L. Hanlon More articles by this author , David Y.T. ChenDavid Y.T. Chen More articles by this author , Richard E. GreenbergRichard E. Greenberg More articles by this author , and Robert G. UzzoRobert G. Uzzo More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)35474-0AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1329: Observation of Enhancing Renal Masses: A Metaanalysis of Worldwide Data." The Journal of Urology, 173(4S), p. 361 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 173Issue 4SApril 2005Page: 361 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Sam N. Chawla More articles by this author Paul L. Crispen More articles by this author Alexandra L. Hanlon More articles by this author David Y.T. Chen More articles by this author Richard E. Greenberg More articles by this author Robert G. Uzzo More articles by this author Expand All Advertisement PDF downloadLoading ...