gebhart/patrepeval huggingface dataset:
Supplementary Figure 2 from Adoptive Cell Therapy for Lymphoma with CD4 T Cells Depleted of CD137-Expressing Regulatory T Cells (2023)

&lt;p&gt;PDF file - 308K, Phenotypic fidelity of transferred T cell subsets.&lt;/p&gt;
A Binding Site for Nuclear Receptors Is Required for the Differential Expression of the Aldolase A Fast-twitch Muscle Promoter in Body and Head Muscles (1998)

In hind limb muscles, the aldolase A muscle-specific promoter is specifically expressed in glycolytic fast-twitch fibers. Here, we show that in addition, it is expressed at higher levels in trunk and limb muscles than in neck and head muscles independent of their fiber-type content. We have identified by analysis of transgenic mice a DNA element that is required for this differential expression and, to a lesser extent, for fiber-type specificity. We show that members of the nuclear receptor superfamily bind this element in skeletal muscle nuclear extracts. Interestingly, in gel mobility shift assays, different complexes were formed with this sequence in tongue nuclear extracts compared with limb or trunk muscle nuclear extracts. Therefore, binding of distinct nuclear receptors to a single regulatory sequence appears to be associated with the location-dependent expression of the aldolase A muscle-specific promoter.
Subcontracted Rational SFE (2005)

In their paper, “Rational Secure Computation and Ideal Mechanism Design, ” Izmalkov, Lepinski and Micali show that any one-shot mediated game can be simulated by the players themselves, without the help of a trusted mediator, using physical envelopes and a ballot-box. We show that communication between the players is not essential to the ILM protocol. That is, we provide a protocol for rational secure function evaluation (Rational SFE) where the players just send a set of envelopes to a referee who simply performs a sequence of publicly verifiable actions. That is, the players can “subcontract ” all of the computation to an untrusted referee. In addition to providing a communication structure that more closely matches the ideal game, our protocol also enables us to better simulate mediated games in which abort is not a dominated action. 1 Prior Work The general notion of secure multi-party computation was put forward and exemplified by Goldreich, Micali and Wigderson [3], based on the two-party results of Yao [6]. In particular,
<title>Mueller matrix measurements of scattered light</title> (1993)

This paper includes a very brief review of Stokes vectors and Mueller matrices. Matrix characteristics are reviewed for a number of different samples--i.e.: isotropic, anisotropic, diffuse, etc. Measurements are given for a number of different samples at both 633 and 1060 nm. This paper relies on hardware descriptions presented in the previous paper in this document.
Abstract 5092: Ziv-aflibercept treatment reduces intra-hepatic tumor growth of a preclinical colorectal carcinoma liver metastasis model, monitored using non-invasive micro-ultrasound and bioluminescent imaging. (2013)

Abstract The liver is a frequent metastatic site for different types of cancers, including colorectal carcinomas (CRC). Therapies that inhibit the angiogenic growth factor VEGF, such as bevacizumab and ziv-aflibercept, are used in combination with chemotherapies to treat metastatic CRC. Ziv-aflibercept (also known as VEGF Trap) is being developed as a part of a collaboration between Sanofi and Regeneron Pharmaceuticals, Inc. and was recently approved by the FDA in metastatic colorectal cancer that is resistant to or has progressed following an oxaliplatin-containing regimen. To better understand the role of VEGF in metastatic CRC, we aimed to assess the effects of ziv-aflibercept on intrahepatic CRC tumor growth, invasion and angiogenesis in a preclinical model. For that we developed and characterized a CRC liver metastasis model that would allow us to longitudinally assess the effects of ziv-aflibercept on CRC growth in the liver parenchyma using non-invasive high frequency micro-ultrasound and bioluminescent imaging modalities. Briefly, luciferase-expressing HCT116 (human colorectal carcinoma) tumor cells were implanted into the left liver lobe of male CB17 SCID mice using image-guided micro-ultrasound. Tumor growth was monitored using both micro-ultrasound and bioluminescent imaging. When tumors were established (approximately 70 mm3), mice were treated with either control protein (hFc, 25 mg/kg, 2x/wk) or ziv-aflibercept (25 mg/kg, 2x/wk) for up to 13 days. Ziv-aflibercept treatment inhibited tumor growth by 95% compared to control treatment. This inhibition of tumor growth was accompanied by significantly decreased cell proliferation (50-70%), as measured by Ki67 immunohistochemistry, and markedly decreased vessel density (approximately 50%), as revealed by CD31 immunohistochemistry. Ziv-aflibercept did not seem to increase tumor invasiveness, as H&amp;E histology did not reveal dramatic differences at the tumor/stroma border between the ziv-aflibercept and control treated tumors. These experiments confirm that ziv-aflibercept reduces growth and vascularity of colorectal tumors growing in the liver in a preclinical model. Citation Format: Alexander P. Adler, Asma Parveen, Gavin Thurston, Alexandra Eichten. Ziv-aflibercept treatment reduces intra-hepatic tumor growth of a preclinical colorectal carcinoma liver metastasis model, monitored using non-invasive micro-ultrasound and bioluminescent imaging. [abstract]. In: Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; 2013 Apr 6-10; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2013;73(8 Suppl):Abstract nr 5092. doi:10.1158/1538-7445.AM2013-5092
Using Rayleigh-Rice to Calculate Smooth-Surface Statistics from the BRDF (2012)

<i>Statistics are no substitute for judgment.</i> - Henry Clay Chapters 2 and 3 have revealed the surface PSD function as the logical path to move back and forth between surface topography and scatter generated by roughness. This chapter concentrates on application of the Rayleigh-Rice relationship to the inverse-scatter problem: the calculation of reflector surface statistics from measured scatter data. This is important because a number of industrial surfaces meet the smooth, clean, front-surface-reflective requirements introduced in Chapter 1, and in these cases, scatter measurement can be used as a fast, noncontact method of microroughness characterization. The special cases of one-dimensional grating-like surfaces and isotropic two-dimensional surfaces receive most of the attention. The conversion of the Rayleigh-Rice diffraction result to the Davies-Bennett TIS relationship is also reviewed. Other than the scatter measurement geometry, the details of how the scatter data is obtained is left for Chapter 7. Chapters 1 - 3 are used as source material. <strong>4.1 Practical Application of the Rayleigh-Rice Perturbation Theory </strong> The use of scatter data as a means of specifying reflector surface quality is a powerful noncontact inspection technique. This chapter discusses the inverse-scatter problem, where BRDF data is used to calculate the PSD and the various surface parameters. Eq. (3.43), introduced in Section 3.3, gives the general relationship between the PSD of an arbitrary, smooth, clean, front-surface reflector and the corresponding scatter pattern, or BRDF. In Eq. (4.1), the terms have been rearranged so that the BRDF is given directly in terms of measurement and sample parameters: (4.1)
ML-Based QoE Estimation in 5G Networks Using Different Regression Techniques (2022)

Monitoring and providing customers with a satisfying Quality of Experience (QoE) is a crucial business incentive for mobile network operators (MNOs). While the MNO is capable of monitoring a vast amount of network-related key performance indicators (KPIs), it typically does not have access to application-specific performance metrics. Among others, this is due to practical obstacles, such as missing standardized interfaces between the network and the application. Existing QoE models allow to map collected KPIs to the user-perceived quality. However, they are not dynamic, cumbersome to obtain, and often rely on application-level information, such as the stalling duration in the case of video streaming. The 5G networking architecture provides new features which can potentially overcome current limitations of in-network QoE monitoring. More specifically, the Application Function (AF) provides a standardized interface for communicating between 5G systems and third parties, such as application providers. The Network Data Analytics Function (NWDAF) is capable of collecting a vast number of network statistics from other 5G network functions and is dedicated to training and deploying Machine Learning (ML) models. This opens new possibilities, unimaginable for earlier mobile network generations, to dynamically learn the relationship between network KPIs and QoE by utilizing ML. Besides elaborating on how the new capabilities introduced with 5G can support an ML-based QoE estimation, we perform a simulation-based feasibility study which evaluates the estimation accuracy of different state-of-the-art regression techniques. In addition, we discuss them with respect to various qualitative aspects from an MNO’s point of view.
The spatial relation of diabetic retinal neurodegeneration with diabetic retinopathy (2020)

RNFL and GCL both showed thinning over time, which was more pronounced in eyes with DR for GCL. This holds true even in regional parts of the retina, as quadrant analyses showed similar results, showing that structural DRN is associated with DR per quadrant independently.
Monitoramento do corante pararosanilina em amostras biológicas (2010)

O corante pararosanilina (P) é um pigmento que apresenta um relevante papel na análise de substâncias química e bactérias do tipo Gram positivo e negativo, além de outros microorganismos. Os ensaios potenciométricos de P mostraram que o corante é um ácido monoprótico e fraco (pKa= 8,78); enquanto a espectrofotometria permitiu estimar seu coeficiente de absortividade molar (ε) igual a 1,48x10(4) mol-1 cm-1 L. A curva analítica para a determinação de P apresenta linearidade entre 7,36x10-6 a 7,36x10-5 mol L-1 e a metodologia foi aplicação em amostras biológicas.
Degradation kinetics of CIGS solar cells (2009)

The moisture-induced degradation rate of CIGS solar cells at 22-85°C and 0-100% RH has been measured and fit to a kinetic rate expression. This expression is coupled to a model of moisture diffusion into a package and typical meteorological input data to create a cumulative damage model to predict lifetime of packaged cells. Analytic solutions are also derived. In the diffusion-controlled regime, the life depends on the square root of package permeability and cell degradation rate. Early results indicate that a barrier of < 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-4</sup> g/m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> /day or better will be required to assure 20 year lifetime in Miami for the global solar cells used here. Other less stable cells will require 10-100X better moisture barrier. Estimated acceleration factors for damp heat (85C/85%RH) vs. Miami range from 15X to 50X, depending on the package, since diffusion through the package is accelerated differently than the cell degradation kinetics. These low accelerations are a direct result of the square root dependence in this diffusion-controlled process.
Mach number effects on conical surface features of swept shock-wave/boundary-layer interactions (1990)

A joint experimental and computational study is made of the shock-wave turbulent boundary-layer interaction generated by sharp fins, with emphasis on Mach-number effects. The Mach number range is from 2 to 4 and the unit Reynolds number is from 50 to 80 million per meter. Fin angles are varied from 4 to 22 deg. Surface-flow patterns are obtained using a color surface-flow-visualization technique. The results show that the upstream-influence response in the conical far-field region is a function of the freestream Mach number and the shock strength. A new interpretation of the behavior of the upstream influence with changes of the inviscid shock angle is given. Agreement between the experimental and the computed upstream-influence lines becomes poorer for stronger interactions, with the computations underpredicting the upstream-influence line.
Reduced-Complexity Power-Efficient Wireless OFDMA using an Equally Probable CSI Quantizer (2007)

Emerging applications involving low-cost wireless sensor networks motivate well optimization of multi-user orthogonal frequency-division multiple access (OFDMA) in the power-limited regime. In this context, the present paper relies on limited- rate feedback (LRF) sent from the access point to terminals to acquire quantized channel state information (CSI) in order to minimize the total average transmit-power under individual average rate and error probability constraints. Specifically, we introduce two suboptimal reduced-complexity schemes to: (i) allocate power, rate and subcarriers across users; and (ii) design accordingly the channel quantizer. The latter relies on the solution of (i) to design equally probable quantization regions per subcarrier and user. Numerical examples corroborate the analytical claims and reveal that the power savings achieved by our reduced-complexity LRF designs are close to those achieved by the optimal solution.
Progress in Clinical Neurosciences: Canadian Guidelines for the Development of Antidementia Therapies: A Conceptual Summary (2006)

The magnitude of the problems faced by an aging Canadian society has been clearly identified. Perhaps the single most important problem is the increasing incidence of dementia. Alzheimer's disease (AD) accounts for 50-60% of the dementias in later life within a spectrum of other contributing dementias. Regulatory approval has been given to Acetylcholinesterase inhibitors for the symptomatic treatment of mild to moderate AD, and conditional approval to memantine for the symptoms of moderate to severe AD. There has been no regulatory approval for the treatment of the degenerative dementias beyond AD. The very rapid progress in the past decade in biotechnology and in the molecular biology of the dementias is supporting a new generation of innovative treatment strategies that will more directly target the underlying disease pathogenic mechanisms. Such treatments will foreseeably include immunotherapies, anti-aggregants that may prevent misfolding and deposition of proteins, and neuroregenerative interventions. These Guidelines follow the 2nd Canadian Conference on the Development of Antidementia Therapies, held in 2004, which covered a range of design, methodological and ethical issues facing clinical researchers and regulatory authorities. They are intended to provide a common point of reference and guidance in Canada for therapeutic development of the dementias.
Supplementary Figure S2 from RhoB Determines Tumor Aggressiveness in a Murine EGFR<sup>L858R</sup>-Induced Adenocarcinoma Model and Is a Potential Prognostic Biomarker for Lepidic Lung Cancer (2023)

&lt;p&gt;Supplementary Figure S2. Western blot of RhoB and EGFRL858R from protein lysate of healthy lungs and lung tumors from EGFR/rhob mice, with corresponding quantification of RhoB protein level; Representative microscopic view of H&amp;E-stained or EGFRL858R or Ki-67-stained healthy and tumor mouse lungs&lt;/p&gt;
Micro-X-ray Fluorescence Characterization of Mixed Oxide Fuel Surrogate Feed Material (1998)

Mixed oxide (MOX) fuel feed material surrogates composed of Ga2O3 in CeO2 were characterized by X-ray fluorescence (XRF) and micro-X-ray fluorescence (MXRF). This work is significant because MOX fuel contains trace levels of Ga2O3 that could potentially damage the fuel cladding. Because a majority of Ga2O3 is extracted during MOX fuel feed processing via reduction to volatile and mobile Ga2O, XRF spatially resolved spot analyses, line scans, and elemental maps were acquired to determine the gallium distribution in surrogate pellets. These modes of analyses, when combined, provided a comprehensive picture of the sample gallium dispersal. The surrogate pellets were reduced at temperatures ranging from 600 to 1200 °C with 6% hydrogen in argon, and the internal gallium was found to migrate toward the outer surface and top of the pellets. This process was more kinetically favorable with increasing reduction temperature. Different quantities of surrogate powders were also reduced from 600 to 1200 °C, and XRF quantitative analysis demonstrated that more gallium was eliminated from the smaller sample lots (as well as at higher temperatures) due to the hydrogen diffusing more effectively into the smaller mass powder samples.
Soundtrack classification by transient events (2011)

We present a method for video classification based on information in the soundtrack. Unlike previous approaches which describe the audio via statistics of mel-frequency cepstral coefficient (MFCC) features calculated on uniformly-spaced frames, we investigate an approach to focusing our representation on audio transients corresponding to sound-track events. These event-related features can reflect the "foreground" of the soundtrack and capture its short-term temporal structure better than conventional frame-based statistics. We evaluate our method on a test set of 1873 YouTube videos labeled with 25 semantic concepts. Retrieval results based on transient features alone are comparable to an MFCC-based system, and fusing the two representations achieves a relative improvement of 7.5% in mean average precision (MAP).
Analysis of Complementary RRAM Switching (2012)

A novel procedure to decompose the I- V switching curves of complementary resistive switching (CRS) RRAM cells into the intrinsic switching characteristics of its individual constituting elements is proposed based on the set behavior of HfO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> -based bipolar RRAM elements. Analysis of different types of complementary cells indicates that very similar intrinsic switching behaviors occur in strongly different types of bipolar switching RRAM, however with a strong material dependence of the characteristic switching voltage.
Coombs’ crossmatch after negative antibody screening - a retrospective observational study comparing the tube test and the microcolumn technology (2009)

Background The antiglobulin crossmatch (AHG XM) is mandatory in Germany and Austria for all patients scheduled for red blood cell (RBC) transfusions. We assessed how many biological relevant RBC alloantibodies are identified by the AHG XM in patients with negative antibody screen (ABS), comparing two screening methods: the conventional tube test (CTT) and the microcolumn technology (MCT). Materials and Methods All AHG XMs performed in the Department of Transfusion Medicine, University Greifswald, were retrospectively analysed for an eight year period. Data source included test results for ABS, AHG XMs and antibody identification. The study period consisted of three parts: (1) 2-cell ABS and XM by CTT; (2) 2-cell ABS and XM by MCT; (3) 3-cells ABS and XM by MCT. Results A total of 312 275 AHG XMs were assessed: 105 647 CTT and 206 628 MCT (after 2-cell ABS: 80 295 and after 3-cell ABS 126 333). There was a fivefold increase in reactive AHG XMs using MCT compared to CTT XMs (0·25% vs. 0·05% respectively; P < 0·001). Excluding anti-A1, other RBC alloantibodies were found with a very low frequency regardless of the method used [CTT 5/105 647 (0·005%), MCT 3/80 295 + 2/126 333 (0·002%); P = 0·3]. RBC alloantibodies were identified in only 1% of the reactive MCT XMs. The two RBC alloantibodies identified after 3-cell ABS were of minor clinical relevance (anti-P1, anti-M). Conclusion When an AHG XM becomes reactive after negative ABS result, this is caused with very few exceptions by clinically irrelevant reactivities. This especially accounts for reactive AHG XM using the MCT.
Spray‐Flame‐Synthesized LaCo1−xFexO3 Perovskite Nanoparticles as Electrocatalysts for Water and Ethanol Oxidation (2019)

Abstract Coupling electrochemical generation of hydrogen with the concomitant formation of an industrially valuable product at the anode instead of oxygen can balance the high costs usually associated with water electrolysis. We report the synthesis of a variety of nanoparticulate LaCo 1− x Fe x O 3 perovskite materials through a specifically optimized spray‐flame nanoparticle synthesis method, using different ratios of La, Co, and Fe precursor compounds. Structural characterization of the resulting materials by XRD, TEM, FTIR, and XPS analysis revealed the formation of mainly perovskite‐type materials. The electrocatalytic performance of the formed perovskite‐type materials towards the oxygen evolution reaction and the ethanol oxidation reaction was investigated by using rotating disk electrode voltammetry. An increased Fe content in the precursor mixture leads to a decrease in the electrocatalytic activity of the nanoparticles. The selectivity towards alcohol oxidation in alkaline media was assessed by using the ethanol oxidation reaction as a model reaction. Operando electrochemistry/ATR‐IR spectroscopy results reveal that acetate and acetaldehyde are the final products, depending on the catalyst composition as well as on the applied potential.
UWB wide slot antenna with band-notch function (2006)

A novel UWB wide slot antenna that has both enhanced impedance bandwidth enough to cover UWB systems and band-notch function of 5 GHz WLAN band limited by IEEE 802.11a and HIPERLAN/2 is proposed. To achieve these two characteristics of wide bandwidth and partial band-notch, a fork-shaped and tapered microstrip feed line and conductor lines in the slot are used, respectively. From the results, it is observed that wide bandwidth from 3.1 to 10.6 GHz for the VSWR<2 is achieved, while 5.15 ~ 5.825 GHz is band-notched
Roadmap on emerging hardware and technology for machine learning (2020)

Recent progress in artificial intelligence is largely attributed to the rapid development of machine learning, especially in the algorithm and neural network models. However, it is the performance of the hardware, in particular the energy efficiency of a computing system that sets the fundamental limit of the capability of machine learning. Data-centric computing requires a revolution in hardware systems, since traditional digital computers based on transistors and the von Neumann architecture were not purposely designed for neuromorphic computing. A hardware platform based on emerging devices and new architecture is the hope for future computing with dramatically improved throughput and energy efficiency. Building such a system, nevertheless, faces a number of challenges, ranging from materials selection, device optimization, circuit fabrication and system integration, to name a few. The aim of this Roadmap is to present a snapshot of emerging hardware technologies that are potentially beneficial for machine learning, providing the Nanotechnology readers with a perspective of challenges and opportunities in this burgeoning field.