gebhart/patrepeval huggingface dataset:
Design, construction, and measurement of a dielectric single-mirror two-stage (DSMTS) photovoltaic concentrator (2001)

The 30 X DSMTS is a trough-like photovoltaic concentrator, meant to track the sun in one axis, which has a mirror allocating two concentration stages and a secondary lens that increases its acceptance up to +/- 2.3 degrees. Provided that the sun subtends an angle of +/- 0.256 degrees, such acceptance seems excessive. However, thanks to it, we can relax requirements that often demand accuracy in systems of the kind. For instance, the shape of the mirror can be achieved by simply bending an aluminum sheet. To foresee the results we may expect of this strategy, we carried out some mechanical calculations, whose results are the boundary conditions that lead to a minimum standard deviation on the local slope of the elastic mirror with regards to the theoretical value. We checked by ray tracing that such an error actually provoked a small decrease on the acceptance. This fact persuaded us to carry out the manufacture of two elastic prototypes. In the test that have been performed so far with them we achieved an acceptance angle of +/- 1.63 degrees and a collection efficiency of 98 percent at a geometrical concentration of 30 times, results that can be considered as outstanding in the photovoltaics framework.
Measurement scheme of the Berry phase in superconducting circuits (2006)

We present a measurement scheme for observing the Berry phase in a flux assisted Cooper pair pump---the Cooper pair sluice. In contrast to the recent experiments, in which the sluice was employed to generate accurate current through a resistance, we consider a device in a superconducting loop. This arrangement introduces a connection between the pumped current and the Berry phase accumulated during the adiabatic pumping cycles. From the adiabaticity criterion, we derive equations for the maximum pumped current and optimize the sluice accordingly. These results apply also to the high accuracy pumping which results in a potential candidate for a metrological current standard. For measuring the pumped current, an additional Josephson junction is installed into the superconducting loop. We show in detail that the switching of this system from superconducting state into normal state as a consequence of an external current pulse through it may be employed to probe the pumped current. To our knowledge the experimental realization of our scheme would be the first observation of the Berry phase in superconducting circuits.
829 HEPATITIS C VIRUS AND LIPID DROPLETS: LIPIDOMIC PROFILING OF HCV CORE PROTEIN-EXPRESSING HEPATOMA CELLS (2012)

2.9 (±0.4) and 0.52 (±0.08) uM, respectively. The CC50 of NDGA and M4N was 54 and >150uM, respectively. At the ED50, the CI of M4N with telaprevir was 0.66 and with boceprevir was 0.58. The CI of M4N with simvastatin was 0.50 and with fluvastatin was 0.48. The CI of M4N with NS5B nucleoside inhibitor 2’-C-methyladenosine was 0.48. Conclusion: Based on the EC50s and CC50s, M4N is a more potent compound than NDGA, roughly 5-fold throughout the three assays and has an improved selectivity index. The CIs show M4N to have moderate synergistic interactions with NS3 PIs, a NS5b nucleoside inhibitor, and with HMG-CoA reductase inhibitors. In conclusion, M4N and NDGA not only exhibit anti-HCV activity but also interact synergistically with other HCV antivirals making them an attractive candidate for HCV therapy. Moreover, NDGA derivatives will be novel antivirals through their action on cellular targets involved with lipid metabolism. Beneficial aspects of indirectly targeting viral replication in this manner include an expected high barrier to resistance and broad genotype coverage.
Burrowing as a non‐reflex behavioural readout for analgesic action in a rat model of sub‐chronic knee joint inflammation (2013)

Burrowing performance is an alternative non-reflex readout relying on innate rodent behaviour that is affected by nociceptive behaviour and can be pharmacologically manipulated. The burrowing assay appears to be more sensitive than OF assays and is as sensitive as WB assays at distinguishing between analgesic doses and doses that impair locomotion.
Advanced Solid-state Lasers - to Ignition and Beyond (1998)

This brochure concentrates on the diode-pumped solid-state laser. Surrounding it on the cover are some of the primary technological developments that make it a candidate for the means by which inertial confinement fusion will create inertial fusion energy as an inexhaustible source of electric power.
Antifouling Properties of Pluronic and Tetronic Surfactants in Digital Microfluidics (2023)

Fouling at liquid-solid interfaces is a pernicious problem for a wide range of applications, including those that are implemented by digital microfluidics (DMF). There are several strategies that have been used to combat surface fouling in DMF, the most common being inclusion of amphiphilic surfactant additives in the droplets to be manipulated. Initial studies relied on Pluronic additives, and more recently, Tetronic additives have been used, which has allowed manipulation of complex samples like serum and whole blood. Here, we report our evaluation of 19 different Pluronic and Tetronic additives, with attempts to determine (1) the difference in antifouling performance between the two families, (2) the structural similarities that predict exceptional antifouling performance, and (3) the mechanism of the antifouling behavior. Our analysis shows that both Pluronic and Tetronic additives with modest molar mass, poly(propylene oxide) (PPO) ≥50 units, poly(ethylene oxide) (PEO) mass percentage ≤50%, and hydrophilic-lipophilic balance (HLB) ca. 13-15 allow for exceptional antifouling performance in DMF. The most promising candidates, P104, P105, and T904, were able to support continuous movement of droplets of serum for more than 2 h, a result (for devices operating in air) previously thought to be out of reach for this technique. Additional results generated using device longevity assays, intrinsic fluorescence measurements, dynamic light scattering, asymmetric flow field flow fractionation, supercritical angle fluorescence microscopy, atomic force microscopy, and quartz crystal microbalance measurements suggest that the best-performing surfactants are more likely to operate by forming a protective layer at the liquid-solid interface than by complexation with proteins. We propose that these results and their implications are an important step forward for the growing community of users of this technique, which may provide guidance in selecting surfactants for manipulating biological matrices for a wide range of applications.
Self-enhanced diffraction from fixed photorefractive gratings during coherent reconstruction (1993)

We explore, theoretically and experimentally, the effects of self-enhancement (or self-depletion) of the diffraction which occurs during coherent reconstruction from fixed photorefractive gratings. These effects are caused by interference between a secondary grating, which forms between the readout and the reconstructed beams, and the fixed grating.
ChemInform Abstract: A Novel Transformation of Primary Amines to N‐Monoalkylhydroxylamines. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Late-Expiratory Activity: Emergence and Interactions With the Respiratory CPG (2010)

The respiratory rhythm and motor pattern are hypothesized to be generated by a brain stem respiratory network with a rhythmogenic core consisting of neural populations interacting within and between the pre-Bötzinger (pre-BötC) and Bötzinger (BötC) complexes and controlled by drives from other brain stem compartments. Our previous large-scale computational model reproduced the behavior of this network under many different conditions but did not consider neural oscillations that were proposed to emerge within the retrotrapezoid nucleus/parafacial respiratory group (RTN/pFRG) and drive preinspiratory (or late-expiratory, late-E) discharges in the abdominal motor output. Here we extend the analysis of our previously published data and consider new data on the generation of abdominal late-E activity as the basis for extending our computational model. The extended model incorporates an additional late-E population in RTN/pFRG, representing a source of late-E oscillatory activity. In the proposed model, under normal metabolic conditions, this RTN/pFRG oscillator is inhibited by BötC/pre-BötC circuits, and the late-E oscillations can be released by either hypercapnia-evoked activation of RTN/pFRG or by hypoxia-dependent suppression of RTN/pFRG inhibition by BötC/pre-BötC. The proposed interactions between BötC/pre-BötC and RTN/pFRG allow the model to reproduce several experimentally observed behaviors, including quantal acceleration of abdominal late-E oscillations with progressive hypercapnia and quantal slowing of phrenic activity with progressive suppression of pre-BötC excitability, as well as to predict a release of late-E oscillations by disinhibition of RTN/pFRG under normal conditions. The extended model proposes mechanistic explanations for the emergence of RTN/pFRG oscillations and their interaction with the brain stem respiratory network.
Supplementary Figure S1 - S7 from Dual Src and MEK Inhibition Decreases Ovarian Cancer Growth and Targets Tumor Initiating Stem-Like Cells (2023)

&lt;p&gt;Supplemental Fig S1. Effects of MEK and Src siRNA and drug inhibitors on cell cycle and signaling; Supplemental Fig S2. Quantitative densitometric analysis of Western blots shown in Figure 2 G &amp; H for p27, pSrc, and pMAPK; Supplemental Fig S3. Effects of long-term saracatinib exposure to increase MEK and upstream kinase activation; Supplemental Fig S4. Densitometry of Western blots in Figure 3; Supplemental Fig S5. Additional data from GSEA; Supplemental Fig S6. Supplemental data for stem cell quantitation in PEO1R, OCI-C5x, OCI-P5x and OCI-U1a; Supplemental Fig S7. Photomicrographs of Ki67, Caspase 3 and ALDH1 in xenograft tumors in Figure 6A.&lt;/p&gt;
All‐copper Flow Batteries (2023)

In this chapter, an overview of current insights of the all-copper Flow Battery (CuFB) is presented and discussed. Although early investigations in all-copper battery systems were already addressed in the mid-1970s, the first practical approach of CuFBs appeared in 2014. The system consists of a hybrid FB based on chloride-rich aqueous electrolytes, where Cu(I)/Cu(II) and Cu 0 /Cu(I) are the redox couples involved in the reactions at the positive and negative half-cells respectively, providing an open circuit voltage of 0.65 V. The composition of the supporting electrolyte strongly affects the electrochemical and physical properties of the copper species, which needs to be carefully selected to ensure the stability of cuprous species, high conductivity and low density and viscosity, enhancing reversibility, kinetics, and stability in solution. HCl and CaCl 2 , as well as mixtures thereof, have been widely investigated as supporting electrolytes providing excellent results. Also, the use of a variety of electrode materials has been proposed, attending to performance and cost criteria. Finally, low-cost polymeric separators and microporous membranes have shown great potential for their application in CuFBs. The use of non-expensive materials coupled with the excellent electrochemical performance and the high availability and recyclability of copper, place this technology well ahead in terms of cost-effectiveness and sustainability compared to other FBs. Different prototypes of the CuFB at laboratory scale have been developed so far, showing promising results. Ongoing research is focused on the optimization of the stack design and in the scale-up of these prototypes up to kW level.
IC‐P‐088: Age correlates with cortical acetylcholinesterase decline in Alzheimer's disease patients: A PET study (2012)

Early onset Alzheimer's disease (EOAD), defined by age of onset Early onset Alzheimer's disease (EOAD), defined by age of onset below 65, and late onset Alzheimer's disease (LOAD), defined by age of onset above 65 differs in clinical manifestations, disease progression, genetic background and neuroimaging findings. Age seems to play an important role in the pathophysiology of Alzheimer's disease (AD). To elucidate the influence of age in the cholinergic function of AD, we measured brain acetylcholinesterase (AChE) activity by using positron emission tomography in patients with EOAD and LOAD. Participants were 22 EOAD (age 59.5 ± 5.3, MMSE 16.9 ± 4.2, duration 2.8 ± 1.6) 26 LOAD (age 74.0 ± 5.2, MMSE 18.3 ± 4.2, duration 1.5 ± 0.8) and 16 healthy control (HC: age 63.3 ± 11.0, MMSE 28.3 ± 1.1) (mean ± SD). Forty minutes dynamic scan with arterial blood sampling was conducted after intravenous injection of N -[11 C]- methyl-4-piperidyl acetate ([11 C]MP4A). Realignment, spatial normalization and smoothing were performed by SPM2 and 2 tissue 3 parameter model non-linear least square estimation was used to calculate voxel-wise brain AChE activity. Brain mask excluding cerebellum and striatum was applied. Voxel-based group comparison and correlation analysis were performed followed by VOI analysis. Clusters were accepted as significant if Family-Wise Error corrected P values<0.05 in cluser-level with extent threshold above 30 voxels. Parametric brain acetylcholinesterase activity difference between early onset and late onset Alzheimer's disease. Parametric group comparison showed that AChE activity was widely attenuated in neocortex of EOAD group while the AChE reduction was relatively restricted to temporo-parietal area in LOAD group. Significant differences between EOAD and LOAD groups were found in bilateral superior temporal and inferior parietal region. Regional AChE activity of left Wernicke's area was positively correlated with age in AD. VOI analysis showed, when compared with HC, mean cortical AChE activity was reduced by 19.0% in EOAD (P<0.001) and 11.5% in LOAD (P<0.001), different between EOAD and LOAD (P = 0.005). Younger age is associated with lower cortical AChE activity in AD patients. Age should be considered as an important factor for AD patients when treating with AChE modulating agents.
Robust and resilient coordination of feeders with uncertain distributed energy resources: from real-time control to long-term planning (2020)

To enable flexible demand and ensure reliable and economical operation of distribution systems, we present a novel hierarchical scheme that actively coordinates responsive behind-the-meter grid resources, including distributed energy resources (DERs), to reliably manage each unbalanced distribution feeder and exploits the available flexibility to economically optimize the entire network. Each layer of the scheme employs advanced optimization methods at different timescales to ensure that the system operates within both grid and device limits. The hierarchy is validated in a large-scale realistic simulation based on data from the industry. Simulation results show that coordination of flexibility improves both system reliability and economics, and enables greater penetration of solar PV. Discussion is also provided on the practical viability of the required communications and controls to implement the presented scheme within a large DSO.
Clock Recovery with DGD-tolerant Phase Detector for CP-QPSK Receivers (2010)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text C. Hebebrand, A. Napoli, A. Bianciotto, S. Calabro, B. Spinnler, and W. Rosenkranz, "Clock Recovery with DGD-tolerant Phase Detector for CP-QPSK Receivers," in Advanced Photonics & Renewable Energy, OSA Technical Digest (CD) (Optical Society of America, 2010), paper SPWB3. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Segmental Unilateral Lentiginosis in Generalized Neurofibromatosis Type 1 (2002)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Neurology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Neurology journal
Peptide Mimotope-Enabled Quantification of Natalizumab Arm Exchange During Multiple Sclerosis Treatment (2022)

In this article, a novel assay for the quantification of unexchanged and exchanged natalizumab variants in clinical samples was developed. This assay will enable investigations into the clinical significance of the relationship of PK/PD with the monovalent-to-bivalent ratio, as it relates to the efficacy of the drug and risk of PML.
Optical Interference Coatings Design Contest 2007: triple bandpass filter and nonpolarizing beam splitter (2007)

A triple bandpass filter (28 solutions received) and a nonpolarizing beam splitter (23 solutions received) were the subjects of the design contest held in conjunction with the 2007 Optical Interference Coatings topical meeting of the Optical Society of America. Fifteen designers participated using a wide spectrum of design approaches and optimization strategies to create the submissions. The results differ significantly, but all meet the contest requirements. Fabien Lemarchand wins both contests by submitting the thinnest (6254 nm) triple bandpass design and the widest (61.7 nm) nonpolarizing beam-splitter design. Michael Trubetskov is in second place, followed by Vladimir Pervak in both contests. The submitted designs are described and evaluated.
Bis(ether-functionalized NHC) Nickel(II) Complexes, Trans to Cis Isomerization Triggered by Water Coordination, and Catalytic Ethylene Oligomerization (2014)

The new nickel(II) complexes containing NHC ligands N-substituted by a CH2CH2OR ether group (R = Me or Ph) [NiCl2{ImMes(C2OMe)}2] (6), [NiCl2{Imn-Bu(C2OMe)}2] (7), [NiBr2{ImDiPP(C2OMe)}2] (8), [NiBr2{ImMes(C2OMe)}2] (9), [NiBr2{Imn-Bu(C2OMe)}2] (10), NiBr2{ImMes(C2OPh)}2] (18), [NiI2{ImDiPP(C2OMe)}2] (21), [NiI2{ImMes(C2OMe)}2] (22), and [NiI2{Imn-Bu(C2OMe)}2] (23) were synthesized in good yields and fully characterized by NMR spectroscopy and X-ray diffraction analysis. The reaction conditions were optimized and further applied to thioether or nonfunctionalized NHC ligands, affording [NiBr2{ImDiPP(C2SPh)}2] (19) and [NiBr2{ImDiPP(n-Bu)}2] (20), respectively. Equilibria involving syn/anti isomers were unveiled for complexes [NiCl2{ImDiPP(C2OMe)}2] (5), 6–10, and 18–23. Reactions of 6 and 20 with a halide abstractor afforded the dicationic aquo complexes cis-[Ni{ImMes(C2OMe)}2(H2O)2][PF6]2 (27) and cis-[Ni{ImDiPP(n-Bu)}2(H2O)2][PF6]2 (28), in which a cis arrangement of the carbene ligands is evidenced, which contrasts with that in their precursors. These molecules represent rare examples of nickel aquo NHC complexes and of complexes with two cis monodentate NHC ligands. The new complexes reported in this work (15 crystal structures) displayed moderate activities as precatalysts for ethylene oligomerization and favored dimerization.
Validation of a lower radiation computed tomography enterography imaging protocol to detect Crohnʼs disease in the small bowel (2010)

Lower radiation dose CTE exams are sensitive for the detection of active small bowel CD. The combination of mural thickness and hyperenhancement are the best radiologic predictors of active CD.
Amplified spontaneous emission rejection with multi-functional MEMS tunable filter (2010)

A multi-functional microelectromechanical system (MEMS) tunable optical filter as an amplified spontaneous emission (ASE) rejection filter in an optical communication system is presented. The MEMS tunable filter can tune both the centre wavelength and the passband independently and continuously in C-band. This filter was applied to a 10 Gbit/s system and system-performance improvement by adjusting the amount of ASE noise rejection was observed.
A General Mechanism for RTP Header Extensions (2017)

This document provides a general mechanism to use the header extension
feature of RTP (the Real-Time Transport Protocol). It provides the
option to use a small number of small extensions in each RTP packet,
where the universe of possible extensions is large and registration is
de-centralized. The actual extensions in use in a session are signaled
in the setup information for that session. [STANDARDS-TRACK]
Structured LISTA for Multidimensional Harmonic Retrieval (2021)

Learned iterative shrinkage thresholding algorithm (LISTA), which adopts deep learning techniques to optimize algorithm parameters from labeled training data, can be successfully applied to small-scale multidimensional harmonic retrieval (MHR) problems. However, LISTA becomes computationally demanding for large-scale MHR because the matrix size of the learned mutual inhibition matrix exhibits quadratic growth with the signal length. These large matrices consume costly memory/computation resources and require a huge amount of labeled data for training. For MHR problems, the mutual inhibition matrix naturally has a Toeplitz structure, implying the degrees of freedom of the matrix can be reduced from quadratic order to linear order. We thereby propose a structured LISTA-Toeplitz network, which imposes Toeplitz structure on the mutual inhibition matrices and applies linear convolution instead of matrix-vector multiplications in traditional LISTA. Both simulation and field tests for air target detection with radar are carried out to validate the performance of the proposed network. For small-scale MHR problems, LISTA-Toeplitz exhibits close or even better recovery accuracy than traditional LISTA, while the former significantly reduces the network complexity and requires much less training data. For large-scale MHR problems, where LISTA is difficult to implement due to the huge size of the matrices, our proposed LISTA-Toeplitz still enjoys good recovery performance.
A gathering of urologists and urogynecologists in montreal: a report from the 35th annual meeting of the international continence society, august 28-september 2, 2005, montreal, quebec, Canada. (2006)

For four days in late summer 2005, more than 3500 urologists and urogynecologists from around the world gathered at the convention center in Montreal for the 35th Annual Meeting of the International Continence Society (ICS).

The ICS membership includes both urologists and gynecologists. Other than the annual meeting of the American Urological Association, the ICS annual meeting is the most important educational conference for urologists interested in neuro-urology and female urology. The ICS annual meeting is a global event, and the meeting comes to North America only every 4 to 5 years. When this occurs, meeting attendance swells with many North American physicians, bringing extra excitement to the proceedings. In this review, we will highlight some of the most interesting presentations from this year’s ICS meeting.