gebhart/patrepeval huggingface dataset:
CD43 Defines Early Hematopoietic Progenitors Derived from Human Embryonic Stem Cells (hESC). (2004)

Abstract We have demonstrated that co-culture of hESCs with OP9 bone-marrow stromal cells induced efficient hESC differentiation into hematopoietic colony-forming cells (CFCs). During hESC/OP9 co-culture, the first CFCs were detectable 1–2 days after emergence of CD34+ cells (day 4–5 of co-culture) and 3–4 days before generation of CD45+ cells, indicating that early CFCs arose in the CD45- population. To define phenotype of early hematopoietic progenitors, we examined the expression of CD41a, CD43, CD61 and glycophorin A (CD235a) on the CD34+ cells in the course of hESC/OP9 co-culture. The first detectable CD34+ cells expressed a high level of VEGF-R2 (KDR) and were CD41a, CD43, CD61 and CD235a negative. Appearance of CFCs was accompanied with down-regulation of KDR and almost simultaneous expression of CD41a, CD43 and CD235a on the CD34+ cells. CD43+ cells gradually increased thereafter, whereas the expression of CD41a was retained on the subset of CD43+ cells that co-express CD235a and CD61. CD45+ cells emerged within CD43+ population and the most of CD45+ cells did not express CD235a, CD41a or CD61. The expression of CD34 was decreased progressively on CD43+CD41a+CD235a+CD61+ cells, but retained by CD43+CD45+ cells. To assay hematopoietic potential of defined subsets, CD34+ cells were isolated by magnetic sorting and further separated into CD34+ CD43+ and CD34+CD43− cell fractions. In addition, CD34−CD43+ cells were isolated from CD34− fraction. CD34+ selection markedly enriched all types CFCs except of E-CFCs. All GEMM-CFCs were found within CD34+ population and none within CD34−. However, CD34− cell fraction contained E-CFCs and minimal numbers of M-CFCs and GM-CFCs. CD34+ cells were also heterogenous in morphologic appearance and contained endothelial cells that were capable to endocytose Ac-LDL. Positive selection of CD43+ cells resulted in total recovery of all types of CFCs. E-CFCs, which consistently detected in the CD34- fraction, were also recovered by CD43 selection. Morphologically, CD43+ cells comprised a homogenous blast-like population and were lack of endothelial-like cells. Thus, expression of CD43 molecule (leukosialin/sialophorin) is detected on the earliest clonogenic hematopoietic progenitors before expression of CD45, persists on developing hematopoietic cells after their lineage specification and most likely defines the divergence of hematopoiesis from endothelial cells during early development in humans.
Chemically significant interactions between ruthenium ions in oxo-bridged complexes of ruthenium(III) (1975)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChemically significant interactions between ruthenium ions in oxo-bridged complexes of ruthenium(III)Tom R. Weaver, Thomas J. Meyer, S. Ajao Adeyemi, Gilbert M. Brown, Richard P. Eckberg, William E. Hatfield, Eugene C. Johnson, Royce W. Murray, and Darrel UnterekerCite this: J. Am. Chem. Soc. 1975, 97, 11, 3039–3048Publication Date (Print):May 1, 1975Publication History Published online1 May 2002Published inissue 1 May 1975https://pubs.acs.org/doi/10.1021/ja00844a020https://doi.org/10.1021/ja00844a020research-articleACS PublicationsRequest reuse permissionsArticle Views863Altmetric-Citations113LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Congenital Etiology Is an Independent Risk Factor for Complications in Adolescents Undergoing Corrective Scoliosis Surgery: Comparison of In-hospital Comorbidities Using Nationwide KID’s Inpatient Database (2017)

Level III-retrospective review of a prospectively collected database.
RAPID: Enabling Fast Online Policy Learning in Dynamic Public Cloud Environments (2023)

Resource sharing between multiple workloads has become a prominent practice among cloud service providers, motivated by demand for improved resource utilization and reduced cost of ownership. Effective resource sharing, however, remains an open challenge due to the adverse effects that resource contention can have on high-priority, user-facing workloads with strict Quality of Service (QoS) requirements. Although recent approaches have demonstrated promising results, those works remain largely impractical in public cloud environments since workloads are not known in advance and may only run for a brief period, thus prohibiting offline learning and significantly hindering online learning. In this paper, we propose RAPID, a novel framework for fast, fully-online resource allocation policy learning in highly dynamic operating environments. RAPID leverages lightweight QoS predictions, enabled by domain-knowledge-inspired techniques for sample efficiency and bias reduction, to decouple control from conventional feedback sources and guide policy learning at a rate orders of magnitude faster than prior work. Evaluation on a real-world server platform with representative cloud workloads confirms that RAPID can learn stable resource allocation policies in minutes, as compared with hours in prior state-of-the-art, while improving QoS by 9.0x and increasing best-effort workload performance by 19-43%.
Towards Generative Video Compression (2021)

We present a neural video compression method based on generative adversarial networks (GANs) that outperforms previous neural video compression methods and is comparable to HEVC in a user study. We propose a technique to mitigate temporal error accumulation caused by recursive frame compression that uses randomized shifting and un-shifting, motivated by a spectral analysis. We present in detail the network design choices, their relative importance, and elaborate on the challenges of evaluating video compression methods in user studies.
Prostacyclin production by endothelial cells. Effects of sera from normal and hyperlipidemic subjects. (1985)

The influence of hyperlipidemic sera on prostacyclin (PGI2) production by cultured endothelial cells was assessed by comparing sera from three types of hyperlipidemias with sera from normal subjects. Sera prepared from normal whole blood (WBS), platelet-rich plasma (PRPS), and platelet-poor plasma (PPPS) were also compared. Bovine aortic endothelial cells (BAEC) incubated with 25% WBS increased PGI2 synthesis significantly within 1 hour, with little further increase by 16 hours; human umbilical vein endothelial cells (HUEC) incubated with 25% WBS for 1 hour showed no elevation in PGI2, whereas PGI2 levels increased substantially after 16 hours. PPPS and PRPS stimulated PGI2 synthesis by BAEC equally at 1 hour. However, there was no rise in PGI2 after PPPS in HUEC; PGI2 rose after 16 hours with PRPS and rose further with WBS after 16 hours. Since WBS best enhanced PGI2 production in human endothelial cells, it was chosen for comparison of the effects of hyperlipidemic and normolipidemic sera. PGI2 synthesis by HUEC significantly increased upon incubation with WBS from Types IIb and IV patients in comparison to WBS from Type IIa hypercholesterolemic patients or normal controls. In contrast, WBS from all these hyperlipidemic subjects stimulated PGI2 synthesis by BAEC similarly to WBS from controls. We conclude that incubation of human endothelial cells with WBS containing high levels of atherogenic lipoproteins does not reduce PGI2 formation by the cells. Moreover, the time course and the contribution of lipid, plasma, or cellular factors to PGI2 formation vary according to the cell type tested. Caution should be exercised in extrapolating results achieved with serum and cells from the same species to other settings.
Enantioselective Total Synthesis of Callipeltoside A. (2002)

An asymmetric total synthesis of callipeltoside A has been accomplished highlighted by a catalytic enantioselective vinylogous aldol reaction and a boron-mediated anti-aldol reaction influenced by remote stereocontrol.
On the morphology and potential application of polydimethylsiloxane-silica-titania composites (2011)

Polydimethylsiloxane-!,"-diol was used as matrix for the preparation of polysiloxane-SiO 2 -TiO 2 composites through in situ incorporation of silica and titania using a solvent-free sol-gel procedure. For this purpose, oxide precursors tetraethyl-orthosilicate and tetrabutyl-orthotitanate, and a proper condensation catalyst, viz. dibuthyltin dilaurate, were added in pre-established amounts to the polymer. The hydrolysis and condensation reactions take place under mild conditions, with the formation of silicon and titanium oxide networks and polymer crosslinking. The effect of SiO 2 and TiO 2 mass ratio on the morphology of the composites was investigated by scanning electron microscopy (SEM) and X-rays diffraction (XRD), and interpreted in correlation with differential scanning calorimetry (DSC) and energy-dispersive X-ray spectroscopy (EDX) data. The film samples were tested as active elements in actuation devices.
Mechanics and Thermodynamics of Curved Thin Films (2023)

The basic idea of the micromechanical treatment of nonuniform systems is to consider the pressure as a nonisotropic tensor. The representation of the total pressure tensor as a sum of several terms accounting for different kind of interactions is not unique and it needs some additional model considerations. The concept of disjoining pressure as an additional pressure that must be introduced in the macroscopic theory of thin liquid films was first introduced by Derjaguin and Kusakov. The surface tension of a flat interface does not depend on the location of the Gibbs' dividing surface. The thin liquid film is a nonautonomous system: It is always a part of a larger thermodynamic system, and the processes in the film are governed by the processes occurring in the whole system. The fundamental equations can be valid for not only reversible, but also for some sufficiently slow, irreversible processes.
Linker-Dependent Singlet Fission in Tetracene Dimers (2018)

Separation of triplet excitons produced by singlet fission is crucial for efficient application of singlet fission materials. While earlier works explored the first step of singlet fission, the formation of the correlated triplet pair state, the focus of recent studies has been on understanding the second step of singlet fission, the formation of independent triplets from the correlated pair state. We present the synthesis and excited-state dynamics of meta- and para-bis(ethynyltetracenyl)benzene dimers that are analogues to the ortho-bis(ethynyltetracenyl)benzene dimer reported by our groups previously. A comparison of the excited-state properties of these dimers allows us to investigate the effects of electronic conjugation and coupling on singlet fission between the ethynyltetracene units within a dimer. In the para isomer, in which the two chromophores are conjugated, the singlet exciton yields the correlated triplet pair state, from which the triplet excitons can decouple via molecular rotations. In contrast, the meta isomer in which the two chromophores are cross-coupled predominantly relaxes via radiative decay. We also report the synthesis and excited-state dynamics of two para dimers with different bridging units joining the ethynyltetracenes. The rate of singlet fission is found to be faster in the dimer with the bridging unit that has orbitals closer in energy to that of the ethynyltetracene chromophores.
Advanced memory technologies for space and missile systems applications (2012)

Technology status and qualification test results are discussed on two new deep submicron radiation hardened devices including a 64Mb SRAM family and stacked MCM versions of the C-RAM non-volatile memory. Electrical characterization and radiation test results will be discussed.
An energy harvesting wireless sensor node for IoT systems featuring a near-threshold voltage IA-32 microcontroller in 14nm tri-gate CMOS (2016)

A wireless sensor node (WSN) integrates a 0.79mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> near-threshold voltage (NTV) 32-bit Intel Architecture (IA) microcontroller (MCU) in 14nm tri-gate CMOS, along with solar cell, energy harvester, flash memory, sensors and Bluetooth Low Energy (BLE) radio, to enable always-on always-sensing (AOAS) and advanced edge computing capabilities in Internet-of-Things (IoT) systems. The MCU features four independent voltage-frequency islands (VFI), a low-leakage SRAM array, an on-die oscillator clock source capable of operating at sub-threshold voltage, power gating and multiple active/sleep states, managed by an integrated power management unit (PMU). The MCU operates across a wide frequency (voltage) range of 297MHz (1V) to 0.5MHz (308mV), and achieves a peak energy efficiency of 17pJ/cycle at an optimum supply voltage (VOPT) of 370mV, operating at 3.5MHz. The WSN, powered by a solar cell, demonstrates sustained MHz AOAS operation, consuming only 360μW.
Magnetic Resonance Reporter Gene Imaging (2012)

Molecular imaging has undergone an explosive advancement in recent years, due to the tremendous research efforts made to understand and visualize biological processes. Molecular imaging by definition assesses cellular and molecular processes in living subjects, with the targets of following metabolic, genomic, and proteomic events. Furthermore, reporter gene imaging plays a central role in this field. Many different approaches have been used to visualize genetic events in living subjects, such as, optical, radionuclide, and magnetic resonance imaging. Compared with the other techniques, magnetic resonance (MR)-based reporter gene imaging has not occupied center stage, despite its superior three-dimensional depictions of anatomical details. In this article, the authors review the principles and applications of various types of MR reporter gene imaging technologies and discuss their advantages and disadvantages.
2,4,6-Trimethoxybenzoic acid (2001)

In the crystal structure of 2,4,6-tri­methoxy­benzoic acid, C10H12O5, the mol­ecules form hydrogen-bonded chains. The carboxyl group is in a syn conformation. The lone pair of electrons acting as the hydrogen bond acceptor is in an anti orientation.
Towards an I/O tracing framework taxonomy (2007)

There is high demand for I/O tracing in High Performance Computing (HPC). It enables in-depth analysis of distributed applications and file system performance tuning. It also aids distributed application debugging. Finally, it facilitates collaboration within and between government, industrial, and academic institutions by enabling the generation of replayable I/O traces, which can be easily distributed and anonymized as necessary to protect confidential or sensitive information. As a response to this demand for tracing tools, various means of I/O trace generation exist. We first survey the I/O Tracing Framework landscape, exploring three popular such frameworks: LANL-Trace [3], Tracefs [1], and//TRACE [2].We next develop an I/O Tracing Framework taxonomy. The purpose of this taxonomy is to assist I/O Tracing Framework users in formalizing their tracing requirements, and to provide the developers of I/O Tracing Frameworks a language to categorize the functionality and performance of them. The taxonomy categorizes I/O Tracing Framework features such as the type of data captured, trace replayability, and anonymization. The taxonomy also considers elapsed-time overhead and performance overhead. Finally, we provide a case study in the use of our new taxonomy, revisiting all three I/O Tracing Frameworks explored in our survey, to formally classify the features of each.
ChemInform Abstract: TOTALSYNTH. VON CEPHALOTAXUS‐ALKALOIDEN (1973)

Abstract Piperonal (Ia) wird nach bekannten Verfahren in 4 Reaktionsschritten in die Säure (Ib) übergeführt, aus der durch Li‐alanat‐Reduktion der Alkohol (IIa) erhalten wird.
Superfluorescent Single Mode Nd:Fiber Source at 1060 nm (1988)

Miniature broadband optical sources are desirable in fiber optic gyroscopes to reduce nonreciprocal phase error due to polarization cross-coupling, as well as coherent backscattering noise and the optical Kerr effectl The commonly used sources at present are superluminescent laser diodes (SLD). However, these sources generally fail to satisfy the wavelength stability requirement, as their emission wavelength is very sensitive to temperature and optical feedback. In addition, they incur high coupling loss into single-mode fiber, yielding typically a few hundreds of μW of usable power.
Acoustic Denial of Service Attacks on Hard Disk Drives (2018)

Bridging concepts from information security and resonance theory, we propose a novel denial of service attack against hard disk drives (HDDs). In this attack, acoustic signals are used to cause rotational vibrations in HDD platters in an attempt to create failures in read/write operations, ultimately halting the correct operation of HDDs. We perform a comprehensive examination of multiple HDDs to characterize the attack and show the feasibility of the attack in two real-world systems, namely, surveillance devices and personal computers. Our attack highlights an overlooked security vulnerability of HDDs, introducing a new threat that can potentially endanger the security of numerous systems.
Fingerprint Image Enhancement and Rotation Schemes for a Single-Chip Fingerprint Sensor and Identifier (2006)

This paper presents fingerprint image enhancement and rotation schemes that improve the identification accuracy with the pixel-parallel processing of pixels. In the schemes, the range of the fingerprint sensor is adjusted to the finger state, the captured image is retouched to obtain the suitable image for identification, and the image is rotated to the correct angle on the pixel array. Sensor and pixel circuits that provide these operations were devised and a test chip was fabricated using 0.25-μm CMOS and the sensor process. It was confirmed in 150,000 identification tests that the schemes reduce the false rejection rate to 6.17% from 30.59%, when the false acceptance rate is 0.1%.
A Simple NOMA Scheme with Optimum Detection (2018)

Non-Orthogonal Multiple Access (NOMA) has been a hot research topic over the past few years, particularly because it is widely recognized that this technique represents a promising technology for massive Machine-Type Communications (mMTC) in future 5G cellular networks. The NOMA literature today is heavily focused on the so-called Power-Domain NOMA, which requires a strong power imbalance at the receiver between user signals. In some recent papers ([1] and [2]), the present authors revived a NOMA concept introduced back in the year 2000 and completely overlooked in the recent NOMA literature. This NOMA concept, which uses two sets of orthogonal signal waveforms and iterative interference cancellation at the receiver, fully avoids the power imbalance requirements of power-domain NOMA and makes it possible to grant the same data rates and performance levels to different users. In this paper, we first shed further light on the limitations of today's power-domain NOMA and we give insight on the potential of superposing the signals of two user groups with different characteristics instead of superposing two user signals. Next, we propose a new variant of the NOMA technique proposed in [1] and [2], which avoids the use of a complex interference canceler. This scheme achieves a 25% channel overloading factor at a negligible degradation of the signal-to-noise ratio (SNR) using a very simple maximumlikelihood (ML) receiver.
Validation of the prognostic value of MMP‐7 in idiopathic pulmonary fibrosis (2016)

This study confirms that MMP-7 concentrations could be used to accurately predict outcomes across cohorts and centres, when similar collection protocols are applied.
Quality Metrics for Symmetric Graph Drawings (2020)

In this paper, we present a framework for quality metrics that measure symmetry, that is, how faithfully a drawing of a graph displays the ground truth geometric automorphisms as symmetries. The quality metrics are based on group theory as well as geometry. More specifically, we introduce two types of symmetry quality metrics for displaying: (1) a single geometric automorphism as a symmetry (axial or rotational) and (2) a group of geometric automorphisms (cyclic or dihedral). We also present algorithms to compute the symmetry quality metrics in O(n log n) time. We validate our symmetry quality metrics using deformation experiments. We then use the metrics to evaluate existing graph layouts to compare how faithfully they display geometric automorphisms of a graph as symmetries.
Synthesis and Characterization of New Dithienosilole-Based Copolymers for Polymer Solar Cells (2011)

A series of dithienosilole-based copolymers, poly [(4,4'-bis(2-hexyl)dithieno[3,2-b:2',3'-d]silole)-2,6-diyl-alt-(2,1,3-benzothiadiazole)-5,5'-diyl] (P1), poly[(4,4'-bis(2-hexyl)dithieno[3,2-b:2',3'-d]silole)-2,6-diyl-alt-(2,2'-bithiazole)-5,5'-diyl] (P2), poly[(4,4'-bis(2-hexyl)dithieno[3,2-b:2',3'-d]silole)-2, 6-diyl-alt-(10 -methyl-phenothiazine)-3,7-diyl](P3), poly[(4,4'-bis(2-hexyl)dithieno[3,2-b:2',3'-d]silole)-2,6-diyl-alt-(4,7-bis(2-thienyl)-9,10-anthracene)-5,5'-diyl] (P4) were synthesized by the Pd-catalyzed Stille polymerization method. Electron-deficient benzothiadiazole and bithiazole units and electron-rich phenothiazine and anthracene moieties were incorporated into the polymer backbone to obtain the broad absorption spectrum and to improve the hole-transporting characteristics, respectively. The polymer solar cell (PSC) was fabricated with a layered structure of ITO/PEDOT:PSS/polymer:C71-PCBM (1:3)/LiF/Al. The best performance of PSC was obtained at P3:C71-PCBM which reaches a power conversion efficiency (PCE) of 1.18%, with a short circuit current density (J(sc)) of 4.75 mA/cm2, an open circuit voltage (V(oc)) of 0.71 V, and a fill factor (FF) of 0.35 under AM 1.5G irradiation (100 mW/cm2).
Function and Structure of a Smart Card (2002)

Chapter One explains the principle of smart cards using the examples of a few basic smart card applications such as calling cards, contactless cards and dual-interface cards. Construction of the smart card body is illustrated and fundamental dimensions are discussed. A variety of ISO Standards are mentioned and their impact to the smart card industry is outlined.