gebhart/patrepeval huggingface dataset:
On the dynamics of mobilization in swelling-dissolving polymeric systems (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOn the dynamics of mobilization in swelling-dissolving polymeric systemsI. Devotta, V. Premnath, M. V. Badiger, P. R. Rajamohanan, S. Ganapathy, and R. A. MashelkarCite this: Macromolecules 1994, 27, 2, 532–539Publication Date (Print):January 1, 1994Publication History Published online1 May 2002Published inissue 1 January 1994https://pubs.acs.org/doi/10.1021/ma00080a030https://doi.org/10.1021/ma00080a030research-articleACS PublicationsRequest reuse permissionsArticle Views178Altmetric-Citations25LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Gold nanoparticle-doped three-dimensional reduced graphene hydrogel modified electrodes for amperometric determination of indole-3-acetic acid and salicylic acid (2019)

Three-dimensional (3D) networked nanomaterials have attracted great interest because of their unique porous and 3D-networked structures. In this work, a series of gold nanoparticle (AuNP) doped graphene hydrogel nanocomposites (AuNP-GHs) were synthesized through hydrothermal reaction under various conditions. X-ray diffraction (XRD), scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X-ray photoelectron spectroscopy (XPS) were used to characterize the AuNP-GH. The AuNP-GH was used to modify the glassy carbon electrode (GCE) for the detection of indole-3-acetic acid (IAA) and salicylic acid (SA) using chronoamperometric measurements. Under optimum conditions, the AuNP-GH/GCE exhibited linear response to IAA in the ranges of 0.8-4 μM and 4-128 μM, and to SA in the ranges of 0.8-8.4 μM and 8.4-188.4 μM. The detection limits (S/N = 3) were calculated to be 0.21 μM for IAA and 0.22 μM for SA. The proposed sensor showed good sensitivity and stability and hence it was applied in the detection of IAA and SA in spiked samples with satisfactory results.
Cryogenic reactions of gallium with molecular hydrogen and methane (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCryogenic reactions of gallium with molecular hydrogen and methaneZ. L. Xiao, R. H. Hauge, and J. L. MargraveCite this: Inorg. Chem. 1993, 32, 5, 642–646Publication Date (Print):March 1, 1993Publication History Published online1 May 2002Published inissue 1 March 1993https://pubs.acs.org/doi/10.1021/ic00057a026https://doi.org/10.1021/ic00057a026research-articleACS PublicationsRequest reuse permissionsArticle Views312Altmetric-Citations76LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Miniature Vapor Compression System (2008)

The refrigeration industry and the academy have recently come up with many innovative refrigeration concepts for both conventional and non conventional applications. They have addressed some special requirements and also current environmental aspects. This article explores how the conventional vapor compression refrigeration concept combined with innovative engineering approaches can break down barriers to provide very compact and energy efficient refrigeration systems. These compact systems are suited for low cooling capacities, where today’s vapor compression systems are not competitive in terms of size and weight. To show meaningful results, a compact A/C system was developed to provide cold air to an extreme edition gaming laptop, improving its performance. The authors believe that many innovative applications, where portability is a key issue, will stem from this development.
Proteinase-activated receptor 1 antagonism ameliorates experimental pulmonary hypertension (2018)

The specific expression of PAR1 in the pulmonary artery and its up-regulation were suggested to play a critical role in the development and progression of experimental PH in murine models. PAR1 is a potential therapeutic target for the treatment of PH.
A retinoic acid–dependent checkpoint in the development of CD4+ T cell–mediated immunity (2011)

It is known that vitamin A and its metabolite, retinoic acid (RA), are essential for host defense. However, the mechanisms for how RA controls inflammation are incompletely understood. The findings presented in this study show that RA signaling occurs concurrent with the development of inflammation. In models of vaccination and allogeneic graft rejection, whole body imaging reveals that RA signaling is temporally and spatially restricted to the site of inflammation. Conditional ablation of RA signaling in T cells significantly interferes with CD4(+) T cell effector function, migration, and polarity. These findings provide a new perspective of the role of RA as a mediator directly controlling CD4(+) T cell differentiation and immunity.
Matrix-M™ Adjuvant Induces Local Recruitment, Activation and Maturation of Central Immune Cells in Absence of Antigen (2012)

Saponin-based adjuvants are widely used to enhance humoral and cellular immune responses towards vaccine antigens, although it is not yet completely known how they mediate their stimulatory effects. The aim of this study was to elucidate the mechanism of action of adjuvant Matrix-M™ without antigen and Alum was used as reference adjuvant. Adjuvant Matrix-M™ is comprised of 40 nm nanoparticles composed of Quillaja saponins, cholesterol and phospholipid. BALB/c mice were subcutaneously injected once with, 3, 12 or 30 µg of Matrix-M™, resulting in recruitment of leukocytes to draining lymph nodes (dLNs) and spleen 48 h post treatment. Flow cytometry analysis identified CD11b(+) Gr-1(high) granulocytes as the cell population increasing most in dLNs and spleen. Additionally, dendritic cells, F4/80(int) cells, T-, B- and NK-cells were recruited to dLNs and in spleen the number of F4/80(int) cells, and to some extent, B cells and dendritic cells, increased. Elevated levels of early activation marker CD69 were detected on T-, B- and NK-cells, CD11b(+) Gr-1(high) cells, F4/80(int) cells and dendritic cells in dLNs. In spleen CD69 was mainly up-regulated on NK cells. B cells and dendritic cells in dLNs and spleen showed an increased expression of the co-stimulatory molecule CD86 and dendritic cells in dLNs expressed elevated levels of MHC class II. The high-dose (30 µg) of Matrix-M™ induced detectable serum levels of IL-6 and MIP-1β 4 h post administration, most likely representing spillover of locally produced cytokines. A lesser increase of IL-6 in serum after administration of 12 µg Matrix-M™ was also observed. In conclusion, early immunostimulatory properties were demonstrated by Matrix-M™ alone, as therapeutic doses resulted in a local transient immune response with recruitment and activation of central immune cells to dLNs. These effects may play a role in enhancing uptake and presentation of vaccine antigens to elicit a competent immune response.
Orthogonal matched filter detection (2002)

We consider the generic problem of detecting a transmitted signal when one of M known signals is transmitted. Instead of using a classical matched filter (MF) detector, matched to the transmitted signals, we propose using an orthogonal matched filter (OMF) detector, which is matched to a set of orthogonal signals that are closest in a least-squares sense to the transmitted signals. We show that this approach is equivalent to optimally whitening the output of the MF demodulator, and then basing the detection on the whitened output. We provide simulation results which suggest that, in many cases, the OMF detector outperforms the MF detector.
An Efficient Sampling Technique for Off-line Quality Control (1997)

The basic setting of this article is that of parameter-design studies using data from computer models. A general approach to parameter design is introduced by coupling an optimizer directly with the computer simulation model using stochastic descriptions of the noise factors. The computational burden of these approaches can be extreme, however, and depends on the sample size used for characterizing the parametric uncertainties. In this article, we present a new sampling technique that generates and inverts the Hammersley points (a low-discrepancy design for placing n points uniformly in a k-dimensional cube) to provide a representative sample for multivariate probability distributions. We compare the performance of this to a sample obtained from a Latin hypercube design by propagating it through a set of nonlinear functions. The number of samples required to converge to the mean and variance is used as a measure of performance. The sampling technique based on the Hammersley points requires far fewer samples to converge to the variance of the derived distributions. An application to off-line quality control of a continuous-stirred tank reactor illustrates that the Hammersley points require up to 40 times fewer samples to converge to the variance of the derived distribution.
Supramolecular Dendrimers: Convenient Synthesis by Programmed Self‐Assembly and Tunable Thermoresponsivity (2012)

We report here the noncovalent synthesis of thermosensitive dendrimers. Short oligoguanosine strands were linked to the focal point of a dendron by using "click chemistry", and quadruplex formation was used to drive the self-assembly process in the presence of metal ions. The dynamic nature of these noncovalent assemblies can be exploited to create combinatorial libraries of dendrimers as demonstrated by the co-assembly of two components. These supramolecular dendrimers showed thermoresponsive behavior that can be tuned by varying the templating cations or the number of guanines in the oligonucleotide strand.
Rapid solution assays for retroviral integration reactions and their use in kinetic analyses of wild-type and mutant Rous sarcoma virus integrases. (1993)

A rapid method for quantitating products of the oligodeoxynucleotide processing reaction in vitro has been developed to facilitate enzymatic studies of the retroviral integrases. Unlike earlier procedures, this assay does not depend on polyacrylamide gel electrphoresis but separates products by batch adsorption to PEI-cellulose. A joining assay has also been modified, to facilitate measurement of the two distinct steps in the integration reaction under parallel conditions. Since these methods allow quantitation of numerous samples in a short period of time, they are especially useful for investigation of kinetic parameters and to measure the effects of possible inhibitors of integrase. These assay systems were used to examine the enzymatic activity of wild-type Rous sarcoma virus integrase and selected mutant proteins with substitutions of single conserved amino acids. In contrast to previous studies, reactions were performed under conditions of substrate excess, and rates, rather than yields of product generated after a given period of incubation, were determined. The results showed that substitutions of several highly conserved residues in what is most likely an evolutionarily conserved catalytic domain of the integrases resulted in a 4- to 10-fold decrease in the apparent rate of processing relative to wild type, under optimized standard conditions. Changing an invariant acidic residue reduced the rate by approximately 60-fold. When joining activity was determined, the relative effects of the substitutions tested generally paralleled the results with processing. However, with both wild-type and mutant integrase proteins, the linear phase of the joining reaction was preceded by what appears to be an exponential "burst" phase.
Simple Stereospecific Syntheses of (R)-2-Fluorohexanoic Acid Ethyl Ester (1991)

Abstract Simple stereospecific syntheses of 2-fluorohexanoic acid 5 were accomplished by conversion of optically pure L-(+)-norleucine to the optically pure hydroxy acid 3 via the classic diazotization reaction followed by substitution of the hydroxy functionality by the fluoro group. This was accomplished stereospecifically using DAST reagent or more practically by nucleophilic displacement of the corresponding mesyloxy group with fluoride ion.
Indocyanine Green Fluorescence Imaging for Evaluation of Uterine Blood Flow in Cynomolgus Macaque (2012)

Background: Uterine blood flow is an important factor in uterine viability, but the number of blood vessels required to maintain viability is uncertain. In this study, indocyanine green (ICG) fluorescence imaging was used to examine uterine hemodynamics and vessels associated with uterine blood flow in cynomolgus macaque.
Real-Time Kinetic Measurements of the Condensation and Evaporation of D2O Molecules on Ice at 140K < T < 220 K (1999)

The cor. version of Table 7 is given.
Upgrade of the gated laser entrance hole imager G-LEH-2 on the National Ignition Facility (2021)

A major upgrade has been implemented for the ns-gated laser entrance hole imager on the National Ignition Facility (NIF) to obtain high-quality data for Hohlraum physics study. In this upgrade, the single "Furi" hCMOS sensor (1024 × 448 pixel arrays with two-frame capability) is replaced with dual "Icarus" sensors (1024 × 512 pixel arrays with four-frame capability). Both types of sensors were developed by Sandia National Laboratories for high energy density physics experiments. With the new Icarus sensors, the new diagnostic provides twice the detection area with improved uniformity, wider temporal coverage, flexible timing setup, and greater sensitivity to soft x rays (<2 keV). These features, together with the fact that the diagnostic is radiation hardened and can be operated on the NIF for high neutron yield deuterium-triterium experiments, enable significantly greater return of data per experiment.
A Short Total Synthesis of (±)-Epimeloscine and (±)-Meloscine Enabled by a Cascade Radical Annulation of a Divinylcyclopropane (2011)

The first stereoselective synthesis of epimeloscine has been accomplished in 13 total steps with a longest linear sequence of 10 steps. The core of the synthesis takes only five steps, the key ones being acylation, stereoselective tandem radical cyclization of a divinylcyclopropane to make two rings, and group-selective ring-closing metathesis of the resulting divinylcyclopentane to make the last ring.
Large and Stable Refractive Index Change in Photochromic Hybrid Materials (1998)

We have developed new transparent photochromic hybrid organic−inorganic materials in which the photochromic group belongs to the polymer network. These materials involving chemically bonded dithienylethene derivatives were prepared by the sol−gel process in the form of thin films a few microns thick. The thickness and refractive index of the sol−gel films either at 633 or 785 nm were determined both in the colored and discolored state by using the attenuated total reflection (ATR) method. Functionalized sol−gel films showed a large refractive index change in a nonabsorbing spectral region: Δn ≈ 4 × 10-2 at 785 nm. This important variation due to the high photochrome content allowed us to design optical components used in the field of wave guiding.
Numerical Modeling of Flow Characteristics for A Reach Reach from Damietta Branch Using K-ε Turbulence Model.(Dept. C) (2022)

In this research, a meandering reach from Damietta branch was selected and numerically studied. The aim of this study is to find the vulnerable zones subjected to maximum velocities so as to assign the appropriate methodology of training structures for improving and stabilizing flow conditions. This reach is approximately 6.78 km long, which located between km 95.22 and km 102 downstream of El- Roda gauge station. Field data were collected and analyzed for the modeling process. A 3-D model called IRIC (International River Interface Corporative) based on an explicit finite difference method (Abbott-Ionescu scheme) was applied. Therefore, in order to fulfill such objective, K-ɛ turbulence model was employed using upwind scheme of the advection terms. Through the modeling process, it was assumed that the sediment particles move in the bed layer zone only and the direction of sediment transport is the same as direction of flow. The effect of vegetation and interactions between sediment motion and vegetation were added in the modeling process. This model treats vegetation drag effects explicitly through drag terms in the equations of motion. From this study, it was found that the vorticity values through the upstream curve are greater than the corresponding ones in the downstream curve; consequently, the upstream curve is subjected to high water velocity values which may increase the scouring process.
Amazon SageMaker Model Monitor: A System for Real-Time Insights into Deployed Machine Learning Models (2021)

With the increasing adoption of machine learning (ML) models and systems in high-stakes settings across different industries, guaranteeing a model's performance after deployment has become crucial. Monitoring models in production is a critical aspect of ensuring their continued performance and reliability. We present Amazon SageMaker Model Monitor, a fully managed service that continuously monitors the quality of machine learning models hosted on Amazon SageMaker. Our system automatically detects data, concept, bias, and feature attribution drift in models in real-time and provides alerts so that model owners can take corrective actions and thereby maintain high quality models. We describe the key requirements obtained from customers, system design and architecture, and methodology for detecting different types of drift. Further, we provide quantitative evaluations followed by use cases, insights, and lessons learned from more than two years of production deployment.
Psychosocial, sexual, reproductive and menopausal health in women with and without HIV in a high-income setting (2023)

WWH in Denmark have fewer children and close friends, and more often report recurrent loneliness, lacking sexual desire and sexual dysfunction compared to WWOH. No differences were evident in menopausal characteristics.
A New Class of Ethylene—Propylene—Diene Terpolymers Produced from Constrained Geometry Metallocene Catalysts (2001)

Abstract Until recently, ethylene/propylene/diene (EPDM) terpolymers have been manufactured exclusively using vanadium based Ziegler—Natta catalyst systems. The vanadium based catalysts are known to have both product and process limitations. These limitations are due to a complex combination of factors including monomer reactivity, catalyst activity, reactor temperatures and pressures. Single-site metallocene constrained geometry catalyst (CGC) technology enables the manufacture of EPDM terpolymers at higher reactor temperature and catalyst efficiency than standard Ziegler—Natta catalyst systems. The unique combination of monomer, catalyst and process technology enables the manufacture of highly crystalline EPDMs having ethylene contents over 90 wt %. This study investigated these new highly crystalline EPDM terpolymers and their differentiation from commercially available EPDMs. The results indicated that these new EPDMs had very high green strength and barrier properties, yet could be cured by conventional vulcanization techniques. The cure response of these EPDMs to either peroxide or sulfur increased with increasing ethylene content. Sulfur cured vulcanizates had much higher tensile strength than peroxide cured vulcanizates. These new EPDMs demonstrated utility as additives to enhance the abrasion, hot tear, and tensile properties of natural rubber compounds. Sponge compounds, having the unique combination of polyethylene physical properties and the utility of sulfur vulcanization were developed from these new polymers.
Theory and Simulation of Vibrational Coupling in Deuterated Proteins:  Toward a New Structural Probe? (2003)

In this work, we present a theoretical and numerical analysis of the vibrational coupling of two deuterated structural elements in proteins. Depending on the presence and magnitude of coupling between these elements, typically deuterium atoms connected to α carbons, characteristic level splittings of vibrational eigenstates are predicted, which are observable around 2100 cm-1 in a broad and transparent spectral window. This approach is illustrated and substantiated by the application of classical force fields to the simulation of the vibrational density of states of the crambin protein. We discuss the possibility to use this effect to obtain structural information about proteins and suggest experiments to verify our theoretical approach.
Coordinated Control of Wave Energy Converters Subject to Motion Constraints (2016)

In this paper, a generic coordinated control method for wave energy converters is proposed, and the constraints on motion amplitudes and the hydrodynamic interaction between converters are considered. The objective of the control problem is to maximize the energy converted from ocean waves, and this is achieved by coordinating the power take-off (PTO) damping of each wave energy converter in the frequency domain in each sea state. In a case study, a wave energy farm consisting of four converters based on the concept developed by Uppsala University is studied. In the solution, motion constraints, including constraints on the amplitudes of displacement and velocity, are included. Twelve months of sea states, based on measured wave data at the Lysekil test site on the Swedish west coast, are used in the simulation to evaluate the performance of the wave energy farm using the new method. Results from the new coordinated control method and traditional control method are compared, indicating that the coordinated control of wave energy converters is an effective way to improve the energy production of wave energy farm in harmonic waves.