gebhart/patrepeval huggingface dataset:
Actigraphic evidence of persistent sleep disruption following repetitive mild traumatic brain injury in a gyrencephalic model (2023)

We studied the effect of multimodal traumatic brain injuries on daily sleep/activity patterns and related histology. Gyrencephalic ferrets wore actigraphs and received military-relevant brain injuries including shockwaves, strong rotational impact, and variable stress, which were evaluated up to 6 months post injury. Sham and Baseline animals exhibited activity patterns occurring in distinct clusters of high activity, interspersed with periods of low activity. In the Injury and Injury + Stress groups, activity clusters diminished and overall activity patterns became significantly more dispersed at 4 weeks post injury with significant sleep fragmentation. Additionally, the Injury + Stress group exhibited a significant decrease in daytime high activity up to 4 months post injury. At 4 weeks post injury, the reactive astrocyte (GFAP) immunoreactivity was significantly greater in both the injury groups compared to Sham, but did not differ at 6 months post injury. The intensity of immunoreactivity of the astrocytic endfeet that surround blood vessels (visualized with aquaporin 4; AQP4), however, differed significantly from Sham at 4 weeks post injury (in both injured groups) and at 6 months (Injury + Stress only). As the distribution of AQP4 plays a key role in the glymphatic system, we suggest that glymphatic disruption occurs in ferrets after the injuries described here.
Photochemistry and Polymerization Efficiency of Bis-imidazole based Photoinitiator Systems (2003)

Photopolymerization efficiency of an acrylate formulation (Ebecryl 605) under light irradiation at 365 nm has been evaluated by using RTFTIR. The role of various multicomponent photoinitiating systems based on bis imidazole derivatives, in the presence or not of an aminobenzophenone, N-phenylglycine and several iodonium salt derivatives has been emphasized. Excited state processes in these two-, three- or four- component systems have been investigated through time resolved laser spectroscopy. The different photophysical processes and photochemical reactions involved are defined and the role of each partner is discussed : this helps to explain the high performance of the three- and four- component photoinitiating systems.
Nonstructural protein NS1 immunodominant epitope detected specifically in dengue virus infected material by a SELDI‐TOF/MS based assay (2012)

Dengue virus (DV) infection is the most common mosquito-born viral disease of public health significance. Though most patients only suffer from flu-like symptoms, a small group of patients experiences more severe forms of the disease. The viral nonstructural protein 1 (NS1), a secreted protein correlating with viremia, is a key element used for dengue diagnosis with potential implications in severe dengue prognosis. Capture-ELISAs for the early detection of the NS1 protein in the sera during the acute febrile stage are commonly used in routine by diagnostic laboratories. In this study, the detection of NS1 protein in DV-infected material was assessed by an alternative method combining a single NS1-directed monoclonal antibody and the SELDI-TOF/MS technology. According to the epitope mapping, the antibodies used are mainly directed against an immuno-dominant peptide located on the C-terminal part of the protein. The NS1 SELDI-TOF assay is specific, has a sensitivity level close to capture-ELISAs and is potentially useful for a coupled serotyping/detection assay or for the detection of subtle post-translational modifications on the protein.
Non-isoplanatic lens aberration corrections in digital holographic microscopy (2023)

The demand for accurate and sub-nanometer precise overlay measurements in semiconductor industry increases with the shrinking feature sizes in integrated circuits. Overlay, the lateral displacement between two layers allows monitoring the chip fabrication process and is part of an import feedback step. In our approach, a digital holographic microscope measures the complex field of the overlay target using simple optics and an additional reference beam. The measured complex valued field allows us to apply computational algorithms to correct for field-position dependent lens aberrations in a computational efficient manner. We present experimental results that show the capability of our computational aberration correction in the visible and near infrared wavelength regimes.
Sopiiko potilaalleni psykoterapia (2016)

Vain va­jaa kol­mannes suoma­lai­sista psy­ko­te­ra­peu­teista ar­vioi asiak­kai­densa saa­neen riit­tävää oh­jausta psy­ko­te­rapiaan. Psy­ko­te­rapiaa edel­tävä ar­viointi ja oh­jaus edis­tävät hoi­toon sitou­tu­mista ja te­rapian tulok­sel­li­suutta. Po­tilaan muutos­valmius, ky­ky tarkas­tella it­seä ja omia tun­teita se­kä jous­tavuus vuoro­vai­ku­tuk­sessa ­ennus­tavat toden­nä­köi­sempää ky­kyä tera­peut­tiseen työsken­telyyn ja lyhyes­täkin psy­ko­te­ra­piasta ­hyö­ty­miseen. Po­tilaan ja psy­ko­te­ra­peutin hy­vä yhteis­työ­suhde en­nustaa hoito­tu­losta merkit­tä­västi. Poti­lasta on syy­tä val­mentaa ar­vioimaan, minkä­laisen psy­ko­te­ra­peutin kans­sa hän ko­kee voi­vansa muo­dostaa hy­vän yhteis­työ­suhteen. Po­tilaan val­miuksien ja psy­ko­te­rapian tavoit­teiden ol­lessa epä­selviä on syy­tä konsul­toida psy­kiat­rista ­eri­kois­sai­raan­hoitoa.
Weighted sparse signal decomposition (2012)

Standard sparse decomposition (with applications in many different areas including compressive sampling) amounts to finding the minimum ℓ <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sup> -norm solution of an underdetermined system of linear equations. In this decomposition, all atoms are treated `uniformly' for being included or not in the decomposition. However, one may wish to weigh more or less certain atoms, or, assign higher costs to some other atoms to be included in the decomposition. This can happen for example when there is prior information available on each atom. This motivates generalizing the notion of minimal ℓ <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sup> -norm solution to that of minimal weighted ℓ <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sup> -norm solution. On the other hand, relaxing weighted ℓ <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sup> -norm via the weighted ℓ <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1</sup> -norm is challenging. This paper deals with minimal weighted ℓ <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sup> -norm solutions of underdetermined linear systems, provides conditions for their uniqueness, and develops an algorithm for their estimation.
Structure of the high-current relativistic electron beam formed by a coaxial gun with magnetic insulation (1980)

A numerical solution is reported for the problem of the formation of a high-current beam of relativistic electrons in a coaxial diode gun with magnetic insulation. The beam structure and other basic characteristics are analyzed in a comparison with experimental results and analytic solutions based on models.
Effect of Platelet-Derived Growth Factor Receptor-β Inhibition with STI571 on Radioimmunotherapy (2005)

Whereas radioimmunotherapy of hematologic malignancies has evolved into a viable treatment option, the responses of solid tumors to radioimmunotherapy are discouraging. The likely cause of this problem is the interstitial hypertension inherent to all solid tumors. Remarkable improvements in tumor responses to radioimmunotherapy were discovered after the inclusion of STI571 in the therapy regimen. A combination of the tumor stroma-reactive STI571, a potent platelet-derived growth factor receptor-beta (PDGFr-beta) antagonist, and the tumor-seeking radiolabeled antibody B72.3 yielded long-lasting growth arrest of the human colorectal adenocarcinoma LS174T grown as s.c. xenografts in athymic mice. The interaction of STI571 with the stromal PDGFr-beta reduced tumor interstitial fluid pressure (P(IF)) by >50% and in so doing improved the uptake of B72.3. The attenuation of P(IF) also had a positive effect on the homogeneity of antibody distribution. These effects were dose-dependent and under optimized dosing conditions allowed for a 2.45 times increase in the tumor uptake of B72.3 as determined in the biodistribution studies. Single-photon emission computed tomography imaging studies substantiated these results and indicated that the homogeneity of the radioisotope distribution was also much improved when compared with the control mice. The increased uptake of radioimmunotherapy into the tumor resulted in >400% increase in the tumor absorbed radiation doses in STI571 + radioimmunotherapy-treated mice compared with PBS + radioimmunotherapy-treated mice. The improved antibody uptake in response to the attenuation of tumor P(IF) was identified as the primary reason for the growth arrest of the STI571 + radioimmunotherapy-treated tumors. Two related causes were also identified: (a) the improved homogeneity of monoclonal antibody distribution in tumor and (b) the increased tumor radiosensitivity resulting from the improved tumor oxygenation.
New techniques for next generation video coding (2010)

Video coding standards are rapidly evolving with the advance of the video compression techniques. As the state of the art video coding standard, H.264/AVC exhibits superior coding performance improvement over its predecessors. Currently, both VCEG and MPEG are launching their next-generation video coding project, which aims to meet the new requirements future applications may impose on the video coding standard. In this paper, we summarize the progress of those next generation video coding standard projects and existing new video coding techniques. Moreover, we also present details on our implementation of second-order prediction and reduced resolution update, followed by some experimental results.
Directional thermal emission from a leaky-wave frequency-selective surface (2015)

We design, fabricate, and characterize a frequency-selective surface (FSS) with directional thermal emission and absorption for long-wave infrared wavelengths. The FSS consists of an array of patch antennas connected by microstrips, the ensemble of which supports leakywave-type modes with forward and backward propagating branches. The branches are designed to intersect at 9.8 m and have a broadside beam with 20-deg full width at half maximum at this wavelength. The absorption along these branches is near unity. Measurement of the hemispherical directional reflectometer shows good agreement with simulation. The ability to control the spectral and directional emittance/absorptance profiles of surfaces has significant applications for radiation heat transfer and sensing.
16. P (2002)

PreviousNext No AccessEncyclopedic Dictionary of Applied Geophysics, Fourth edition16. PAuthors: Robert E. SheriffRobert E. SheriffProfessor, University of Houstonhttps://doi.org/10.1190/1.9781560802969.chp SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.9781560802969.chpFiguresReferencesRelatedDetails Encyclopedic Dictionary of Applied Geophysics, Fourth editionISBN (print):978-1-56080-118-4ISBN (online):978-1-56080-296-9Copyright: 2002 Pages: 442 publication data© 2002 All rights reserved. No part of this publication may be reproduced or distributed in any form or by any means without written permission of the publisherPublisher:Society of Exploration Geophysicists HistoryPublished in print: 01 Jan 2002 CITATION INFORMATION Robert E. Sheriff, (2002), "16. P," Geophysical References Series : 256-280. https://doi.org/10.1190/1.9781560802969.chp Plain-Language Summary PDF DownloadLoading ...
Rapid Field Analytical Methods for Total Petroleum Hydrocarbons (2017)

Abstract Total Petroleum Hydrocarbons (TPH) in soil is often measured to determine if soils have been impacted by crude oil. PT. Chevron Pacific Indonesia (CPI) operates several oil fields in Sumatra and samples soil for TPH content for remediation-related work. Traditional laboratory methods used to analyze for TPH in soil require three to four days, and commercial labs often take two to four weeks before reporting results. This timing results in delays in decision-making regarding site soil delineation and excavation as well as in determining when soil remediation has been completed. CPI conducted two pilot studies using commercially available rapid TPH test kits and one non-destructive infrared method. In the first pilot study, six different commercially available field test kits were evaluated for rapid TPH analysis plus a modified FTK (field test kit) with infrared method. Each test method was used to measure TPH from 63 soil samples. These samples covered a wide range of soil type, oil content, and moisture content, and should, therefore, be representative of most CPI sites. The TPH results were compared to the standard TPH analytical method, TPH-Gas Chromatography (TPH-GC) (USEPA 8015). In the second pilot study, a portable handheld infrared (IR) Instrument was tested with over 300 soil samples from variable CPI sites. The standard TPH-GC analytical method data of those soil samples were used to create two site-specific models with 15-20 double-blinded samples to validate the modeling work. The validated models will be loaded onto the individual instrument for future field deployment. Two of the six commercially available test methods produced TPH results similar to those obtained by the standard laboratory TPH-GC methods. The rapid, portable IR method also provided TPH results that correlated well with standard TPH-GC results at different concentration levels. The advantage of the rapid IR method is that the soil samples do not have to be extracted with a solvent, so no chemical waste is generated. The rapid IR method provides TPH results in a few minutes rather than in days or weeks. This paper describes the results from the two pilot studies, and the pros and cons of each rapid method for field application are discussed.
Characterization of the tachykinin NK2receptor in the human bronchus: influence of amastatin‐sensitive metabolic pathways (1994)

1. The aim of this study was to characterize the tachykinin NK2 receptor subtype mediating the spasmogenic response in the human isolated bronchus. The motor response to neurokinin A (NKA) and the selective NK2 agonist [beta Ala8]NKA(4-10), as well as the antagonistic effects of cyclic (L659,877) and linear (MEN 10376) peptide NK2 antagonists were assessed in the presence or absence of amastatin (an inhibitor of aminopeptidases A and M). 2. NKA was more potent than [beta Ala8]NKA(4-10) in eliciting bronchoconstriction (pD2 being 7,43 and 6,87 respectively). In the presence of amastatin (1 microM), the estimated affinity of [beta Ala8]NKA(4-10), but not that of NKA, was significantly increased to yield a pD2 of 7,44. 3. L659,877 and MEN 10376 inhibited [beta Ala8]NKA(4-10)-induced contraction with similar affinities; pA2 values were 5.7 +/- 0.22 and 6.3 +/- 0.32, respectively. Amastatin (1 microM) increased the potency of MEN 10376 to 7.28 +/- 0.46, whereas that of L659,877 was unaffected. 4. In the presence of amastatin the pseudopeptide MDL 28,564 behaved as a partial agonist. 5. We conclude that the NK2 receptor subtype present in the human bronchus has properties similar to those described for the circular muscle of the human colon and thus may be classified as a 'NK2A' subtype. We show that the apparent potency of peptides, bearing N-terminal acidic residues, is influenced by an amastatin-sensitive peptidase, possibly aminopeptidase A.
Augmenting interactive tables with mice & keyboards (2009)

This note examines the role traditional input devices can play in surface computing. Mice and keyboards can enhance tabletop technologies since they support high fidelity input, facilitate interaction with distant objects, and serve as a proxy for user identity and position. Interactive tabletops, in turn, can enhance the functionality of traditional input devices: they provide spatial sensing, augment devices with co-located visual content, and support connections among a plurality of devices. We introduce eight interaction techniques for a table with mice and keyboards, and we discuss the design space of such interactions.
Codebook Design for Composite Beamforming in Next-generation mmWave Systems (2022)

In pursuance of the unused spectrum in higher frequencies, millimeter wave (mmWave) bands have a pivotal role. However, the high path-loss and poor scattering associated with mmWave communications highlight the necessity of employing effective beamforming techniques. In order to efficiently search for the beam to serve a user and to jointly serve multiple users it is often required to use a composite beam which consists of multiple disjoint lobes. A composite beam covers multiple desired angular coverage intervals (ACIs) and ideally has maximum and uniform gain (smoothness) within each desired ACI, negligible gain (leakage) outside the desired ACIs, and sharp edges. We propose an algorithm for designing such ideal composite codebook by providing an analytical closed-form solution with low computational complexity. There is a fundamental trade-off between the gain, leakage and smoothness of the beams. Our design allows to achieve different values in such trade-off based on changing the design parameters. We highlight the shortcomings of the uniform linear arrays (ULAs) in building arbitrary composite beams. Consequently, we use a recently introduced twin-ULA (TULA) antenna structure to effectively resolve these inefficiencies. Numerical results are used to validate the theoretical findings.
IS-IS Protocol Extension For Building Distribution Trees (2014)

This document proposes an IS-IS protocol extension to support IGP
based multicast transport architecture and solution [IGP-MCAST].
Enhanced Hydrogen Gas Detection Using SAW Sensor Through Oxygen Pre-Treatment (2019)

Hydrogen gas sensing is crucial in a variety of applications, including power generation, fuel cells, automotive, metallurgic and manufacturing industries. Some of the requirements for a hydrogen sensor are reliability, robustness, stability, fast response and recovery times. Surface acoustic wave (SAW) technology can offer these characteristics, and others such as small size and weight, wireless operation capability including multiple sensor interrogation, mass production reproducibility and low cost. In this work, an improvement in room temperature H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> gas sensor response time and stability is reported through the use of O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> treatments. The exposure to O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , after interaction with H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> , reconditions the Pt-Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> composite thin-film used both as the electrode and H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> sensing layer. As a result, the SAW sensor frequency response recovery is over five times larger during the initial 20 minutes when compared to the exposure to N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> inert gas. In addition, the O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> treatment allows the recovery of the sensor to a state close to the one prior to the reduction by H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> within about an hour, thus leading to a stable device response, which is very difficult to achieve under the inert N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> environment even after tens of hours. The method is thus very promising in recovering the surface of sensing devices which rely on metallic composite electrodes and oxide films exposed to reducing environment.
Crystal Structures of the Clostridium botulinum Neurotoxin A6 Cell Binding Domain Alone and in Complex with GD1a Reveal Significant Conformational Flexibility (2022)

<i>Clostridium botulinum</i> neurotoxin A (BoNT/A) targets the soluble <i>N</i>-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, by cleaving synaptosomal-associated protein of 25 kDa size (<i>SNAP</i><i>-</i><i>25</i>). Cleavage of SNAP-25 results in flaccid paralysis due to repression of synaptic transmission at the neuromuscular junction. This activity has been exploited to treat a range of diseases associated with hypersecretion of neurotransmitters, with formulations of BoNT/A commercially available as therapeutics. Generally, BoNT activity is facilitated by three essential domains within the molecule, the cell binding domain (H<sub>C</sub>), the translocation domain (H<sub>N</sub>), and the catalytic domain (LC). The H<sub>C,</sub> which consists of an N-terminal (H<sub>CN</sub>) and a C-terminal (H<sub>CC</sub>) subdomain, is responsible for BoNT's high target specificity where it forms a dual-receptor complex with synaptic vesicle protein 2 (SV2) and a ganglioside receptor on the surface of motor neurons. In this study, we have determined the crystal structure of botulinum neurotoxin A6 cell binding domain (H<sub>C</sub>/A6) in complex with GD1a and describe the interactions involved in ganglioside binding. We also present a new crystal form of wild type H<sub>C</sub>/A6 (crystal form II) where a large 'hinge motion' between the H<sub>CN</sub> and H<sub>CC</sub> subdomains is observed. These structures, along with a comparison to the previously determined wild type crystal structure of H<sub>C</sub>/A6 (crystal form I), reveals the degree of conformational flexibility exhibited by H<sub>C</sub>/A6.
Hybrid Integration of Semiconductor Optical Amplifier and Silica-based Planar Lightwave Circuit for Low Polarization Dependent Gain (2011)

We demonstrated a semiconductor optical amplifier hybrid-integrated with a silica-based planar lightwave circuits. With deploying polarization diversity circuit, polarization dependent gain was reduced from 22.9 dB to 1.8 dB in C-band.
4.3: Low‐Twist Vertically‐Aligned Transflective LCD (2004)

Abstract In this paper we propose a low‐twist vertically‐aligned transflective liquid crystal display (LCD). By optimizing the twist angle and the chiral pitch, we achieved high reflectance as well as high transmittance.
ChemInform Abstract: BIS(2‐DIPHENYLPHOSPHINOETHYL)AMINE. A FLEXIBLE SYNTHESIS OF FUNCTIONALIZED CHELATING DIPHOSPHINES (1978)

Abstract Bis‐[diphenylphosphinoethyl]‐amin wird als luftstabiles Hydrochlorid (II) aus dem Bis‐[2‐chlorethyl]‐amin (I) nach aufgezeigtem Schema synthetisiert.
Treatment patterns and survival of low and intermediate‐risk prostate cancer in end‐stage kidney disease: A retrospective population cohort study (2023)

The disparity in definitive treatment rates for low-risk prostate cancer among dialysis patients exists despite their high mortality, compared to the general population.