gebhart/patrepeval huggingface dataset:
Combining autoclave and LCWM reactor studies to shed light on the kinetics of glucose oxidation catalyzed by doped molybdenum-based heteropoly acids (2019)

In this work we combined kinetic studies for aqueous-phase glucose oxidation in a high-pressure autoclave setup with catalyst reoxidation studies in a liquid-core waveguide membrane reactor. Hereby, we investigated the influence of Nb- and Ta-doping on Mo-based Keggin-polyoxometalates for both reaction steps independently. Most importantly, we could demonstrate a significant increase of glucose oxidation kinetics by Ta- and especially Nb-doping by factors of 1.1 and 1.5 compared to the classical HPA-Mo. Moreover, activation energies for the substrate oxidation step could be significantly reduced from around 80 kJ mol<sup>-1</sup> for the classical HPA-Mo to 61 kJ mol<sup>-1</sup> for the Ta- and 55 kJ mol<sup>-1</sup> for the Nb-doped species, respectively. Regarding catalyst reoxidation kinetics, the doping did not show significant differences between the different catalysts.
Supplementary Figure 3 from Cotargeting MAPK and PI3K Signaling with Concurrent Radiotherapy as a Strategy for the Treatment of Pancreatic Cancer (2023)

&lt;p&gt;PDF file, 327KB, Treatment of MIA-PaCa-2 cells with API-2 induces potent inhibition of Akt activation at 1 hour, regardless of the presence of PD0325901.&lt;/p&gt;
Evaluation of substrate noise suppression method to mitigate crosstalk among trough-silicon vias (2018)

Substrate noise from a single through-silicon via (TSV) and the noise attenuation by a substrate tap and a guard ring are clarified. A CMOS test vehicle is designed, and 6-µm-diameter TSVs are manufactured on a 20-µm-thick silicon substrate by the via-last method. An on-chip waveform-capturing circuitry is embedded in the test vehicle to capture transient waveforms of substrate noise. The embedded waveform-capturing circuitry demonstrates small and local noise propagation. Experimental results show increased substrate noise level induced by TSVs and the effectiveness of the substrate tap and guard ring for mitigating the crosstalk among TSVs. An analytical model to explain substrate noise propagation is developed to validate experimental results. Results obtained using the substrate model with a multilayer mesh shows good consistency with experimental results, indicating that the model can be used for examination of noise suppression methods.
Object-oriented methods (1994)

From the Publisher:
The field of object orientation has evolved dramatically in the past several years, most recently with the introduction of the United Modeling Language (UML) - a standard approach to notation and modeling for object-oriented analysis and design. Now, world-renowned IT strategist James Martin, together with James Odell - a leader on the UML standardization effortjoin forces to deliver an insightful introduction to object-oriented methods using UML. This timely, authoritative, in-depth exploration of object-oriented analysis gives you a formal foundation for modeling both new software and new business processes. Object orientation and UML enable you to model regardless of language, to organize coherently all the technologies you wish to use, and to create designs that can evolve gracefully as new technologies and approaches come along. Object-Oriented Methods: A Foundation, UML Edition gives you the intellectual framework to make the most of object orientation no matter how you intend to apply it. Odell and Martin introduce more advanced structuresincluding constraints, rules, meta-modeling, power types, and dynamic and multiple classification - which make it possible to describe and specify systems with greater ease and power. They demonstrate the UML's approach to modeling object structure and behavior; review finite-state machine and scenario-based modeling; and present basic considerations for designing and implementing systems modeled with UML.
Mehrfachbindungen zwischen Hauptgruppenelementen und übergangsmetallen, IXL Synthesen, Strukturen und Reaktivität von Phosphan‐, Phosphiniden‐ und Phosphido‐Komplexen des Mangans (1987)

Abstract Bei Einwirkung von Monophosphan (PH 3 ) auf den Solvens‐Komplex (η 5 ‐C 5 Me 5 )Mn(CO) 2 (THF) ( 1 ; Me == CH 3 ) entsteht der Phosphan‐Komplex (η 5 ‐C 5 Me 5 )Mn(CO) 2 (PH 3 ) ( 2 ), dessen nahezu tetraedrische Strukturgeometrie die bisher kürzeste bekannte Mangan‐Phosphor‐Bindung aufweist [ d (Mn–P)=219.1(4) pm, Einkristall‐Röntgenstrukturanalyse]. Photolyse des lichtempfindlichen Komplexes 2 führt unter H 2 ‐Eliminierung zum μ‐Phosphiniden‐Komplex (μ‐PH) [(η‐ 5 ‐C 5 Me 5 )Mn(CO) 2 ] 2 ( 3 ), während Deprotonierung mittels Kaliumhydrid den salzartigen, extrem hydrolyse‐ und luftempfindlichen Phosphido‐Komplex K[(η 5 ‐C 5 Me 5 )Mn(CO) 2 PH 2 ] ( 4 ) liefert. Als übersichtliche neue Syntheseroute zur Darstellung heterodinuclearer μ‐Phosphido‐Komplexe stellt sich die Umsetzung von 4 mit (η 5 ‐C 5 H 5 Fe(CO) 2 I dar; der so zugängliche Zweikernkomplex [(η 5 ‐C 5 Me 5 )Mn(CO) 2 ](μ‐PH 2 ) [(η 5 ‐C 5 H 5 )Fe(CO) 2 ] ( 5 ) enthält eine unsubstituierte Phosphido‐Brücke (PH 2 ) als 3 e ‐Ligand. Der für 5 röntgenographisch ermittelte kurze Mn‐P‐Abstand von 225.9(2) pm läßt auf Mehrfachbindungsanteile schließen (formale Doppelbindung); der Fe–P‐Abstand von 229.1(2) pm ist dagegen eher mit einer Einfachbindung verträglich.
Measurement of the branching fraction of the decay Bs0→KS0KS0 (2020)

A measurement of the branching fraction of the decay B 0 s K 0 S K 0 S is performed using protonproton collision data corresponding to an integrated luminosity of 5 fb -1 collected by the LHCb experiment between 2011 and 2016. The branching fraction is determined to be BB
Convalescent Plasma Therapy for COVID-19: A Graphical Mosaic of the Worldwide Evidence (2021)

Convalescent plasma has been used worldwide to treat patients hospitalized with coronavirus disease 2019 (COVID-19) and prevent disease progression. Despite global usage, uncertainty remains regarding plasma efficacy, as randomized controlled trials (RCTs) have provided divergent evidence regarding the survival benefit of convalescent plasma. Here, we argue that during a global health emergency, the mosaic of evidence originating from multiple levels of the epistemic hierarchy should inform contemporary policy and healthcare decisions. Indeed, worldwide matched-control studies have generally found convalescent plasma to improve COVID-19 patient survival, and RCTs have demonstrated a survival benefit when transfused early in the disease course but limited or no benefit later in the disease course when patients required greater supportive therapies. RCTs have also revealed that convalescent plasma transfusion contributes to improved symptomatology and viral clearance. To further investigate the effect of convalescent plasma on patient mortality, we performed a meta-analytical approach to pool daily survival data from all controlled studies that reported Kaplan-Meier survival plots. Qualitative inspection of all available Kaplan-Meier survival data and an aggregate Kaplan-Meier survival plot revealed a directionally consistent pattern among studies arising from multiple levels of the epistemic hierarchy, whereby convalescent plasma transfusion was generally associated with greater patient survival. Given that convalescent plasma has a similar safety profile as standard plasma, convalescent plasma should be implemented within weeks of the onset of future infectious disease outbreaks.
589: Tissue Engineered Tubularized Urethra for Surgical Reconstruction: A Pre-Clinical Study (2007)

You have accessJournal of UrologyPodium 19, Sunday, May 20, 2007, 3:30 - 5:30 pm1 Apr 2007589: Tissue Engineered Tubularized Urethra for Surgical Reconstruction: A Pre-Clinical Study Hazem O. Orabi, Tamer A. Aboushwareb, Yuan Yuan Zhang, James J. Yoo, and Anthony Atala Hazem O. OrabiHazem O. Orabi More articles by this author , Tamer A. AboushwarebTamer A. Aboushwareb More articles by this author , Yuan Yuan ZhangYuan Yuan Zhang More articles by this author , James J. YooJames J. Yoo More articles by this author , and Anthony AtalaAnthony Atala More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)30829-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "589: Tissue Engineered Tubularized Urethra for Surgical Reconstruction: A Pre-Clinical Study." The Journal of Urology, 177(4S), p. 197 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 177Issue 4SApril 2007Page: 197 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Hazem O. Orabi More articles by this author Tamer A. Aboushwareb More articles by this author Yuan Yuan Zhang More articles by this author James J. Yoo More articles by this author Anthony Atala More articles by this author Expand All Advertisement PDF downloadLoading ...
Unveiling the Interfacial and Structural Heterogeneity of Ti3C2Tx MXene Etched with CoF2/HCl by Integrated in Situ Thermal Analysis (2021)

Ti<sub>3</sub>C<sub>2</sub>T<sub><i>x</i></sub> MXene is a member of the recently discovered two-dimensional early transition metal carbide and nitride family of MXenes with potential applications in energy storage and heterogeneous catalysis at elevated temperatures. Here, we apply a suite of <i>in situ</i> techniques to probe Ti<sub>3</sub>C<sub>2</sub>T<sub><i>x</i></sub> MXene's thermal evolutions, including <i>in situ</i> X-ray diffraction (XRD), <i>in situ</i> diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS), and integrated thermogravimetry-differential scanning calorimetry-mass spectrometry (TG-DSC-MS). In light of this set of <i>in situ</i> investigations, we find heterogeneity in the layering of Ti<sub>3</sub>C<sub>2</sub>T<sub><i>x</i></sub> MXene revealed only at higher temperatures. Our findings present behavior up to 600 °C, particularly interlayer water and -OH surface end-capping groups. In one group of layers, their interlayer spacing shrinks as water deintercalates, but the other group of layers unexpectedly shows no change in the interlayer spacing. This is strong evidence that intercalants act as guest pillaring agents in the latter layering group, which stabilize these layers at higher temperatures while keeping the interlayer space accessible.
A novel 32x32 InP/ InGaAs SPAD array for multi-channel time-gated diffuse correlation spectroscopy (2022)

We present the design of an innovative time-gated 32×32 InP/InGaAs-based Single Photon Avalanche Diode (SPAD) array with sub-nanosecond gating capabilities operating up to 10MHz repetition rate specifically designed for time-domain diffuse correlation spectroscopy at 1064nm. We present the detector design, experimental characterization and preliminary validations on a liquid phantom. This testing is informing us for a revision of the photodetector which will allow to reach up to 192 optical channels towards functional blood flow changes measurements with full head coverage with improved brain sensitivity thanks to early-photons rejection.
Continuous Multistage Synthesis and Functionalization of Sub-100 nm Silica Nanoparticles in 3D-Printed Continuous Stirred-Tank Reactor Cascades (2020)

The controlled and continuous production of nanoparticles (NPs) with functionalized surfaces remains a technological challenge. We present a multistage synthetic platform, consisting of 3D-printed miniature continuous stirred-tank reactor (CSTR) cascades, for the continuous synthesis and functionalization of SiO<sub>2</sub> NPs. The use of the CSTR platform provides ideal and rapid mixing of precursor solutions, precise injection of additional reagents for multistep reactions, and facile operation when using viscous solutions and handling of syntheses with longer reaction times. To exemplify the use of such custom-designed CSTR cascades, amine- and carbohydrate-functionalized SiO<sub>2</sub> NPs are chosen as model reaction systems. In particular, the intensified flow reactor units allowed for the reproducible formation of SiO<sub>2</sub> NPs with diameters less than 100 nm and narrow size distributions (3-8%). Most importantly, by assembling various 3D-printed CSTR cascades, we synthesized gluconolactone-capped polyethylenimine-modified silica NPs in a fully continuous manner. The inherent control over NP surface charge, reactor scalability, and the significant shortening of processing times (less than 10 min) compared to batch methodologies (several days) strongly indicate the ability of the reactor technology to accelerate continuous nanomanufacturing. In general, it provides a simple route for the reproducible preparation of functionalized NPs, thus expanding the gamut of flow reactors for material synthesis.
Selective cleavage in the avian retroviral long terminal repeat sequence by the endonuclease associated with the alpha beta form of avian reverse transcriptase. (1983)

M13 recombinant DNA clones containing a 350-base sequence derived from the EcoRI fragment of two tandemly linked Rous-associated virus 2 (RAV-2) long terminal repeat (LTR) sequences have been used to map reverse transcriptase-associated endonuclease (RT-endonuclease) cleavage sites by primer extension studies. Under appropriate conditions, the alpha beta form of RT-endonuclease (composed of both the alpha and beta subunits) purified from Avian sarcoma virus (Pr-C and B-77 strains) introduces a specific break in the inverted complementary repeat sequence found at the junction of the LTRs. The cleavage sites occur in the same nucleotide sequence in (-) and (+) DNA strands; together they have the potential of generating a 6-base-pair staggered overlap that spans the junction. This supports the notion that the enzyme is involved in viral DNA integration. Other RT-endonuclease sites were analyzed. A second site, which occurs in the lac region of the M13 vector DNA upstream from the unique EcoRI cloning site, bears no apparent sequence homology to the site at the junction of the LTRs. However, it also lies within an inverted complementary repeat and, as is the case for the site in the LTR, the break occurs to the 5' side of the axis of symmetry. Cleavage at this second site is suppressed when the vector contains the RAV-2 LTR insert. Thus, the viral LTR appears to exert a cis effect that can influence a region over 300 base pairs away.
Transcriptional Reversion of Cardiac Myocyte Fate During Mammalian Cardiac Regeneration (2014)

Our work reveals new insights into the transcriptional regulation of mammalian cardiac regeneration and provides the founding circuitry for identifying potential regulators for stimulating heart regeneration.
Understanding the IoT connectivity landscape: a contemporary M2M radio technology roadmap (2015)

This article addresses the market-changing phenomenon of the Internet of Things (IoT), which relies on the underlying paradigm of machine-to-machine (M2M) communications to integrate a plethora of various sensors, actuators, and smart meters across a wide spectrum of businesses. Today the M2M landscape features an extreme diversity of available connectivity solutions which, due to the enormous economic promise of the IoT, need to be harmonized across multiple industries. To this end, we comprehensively review the most prominent existing and novel M2M radio technologies, as well as share our first-hand real-world deployment experiences, with the goal to provide a unified insight into enabling M2M architectures, unique technology features, expected performance, and related standardization developments. We pay particular attention to the cellular M2M sector employing 3GPP LTE technology. This work is a systematic recollection of our many recent research, industrial, entrepreneurial, and standardization efforts within the contemporary M2M ecosystem.
N-(2,6-Dimethylphenyl)-2-methylacetamide (2008)

The structure of the title compound (26DMPMA), C(11)H(15)NO, is closely related to the side-chain unsubstituted N-(2,6-dimethyl-phen-yl)acetamide and side-chain substituted N-(2,6-dimethyl-phen-yl)-2,2,2-trimethyl-acetamide and 2-chloro-N-(2,6-dimethyl-phen-yl)acetamide, with slightly different bond parameters. The mol-ecules in 26DMPMA are linked into chains through N-H⋯O hydrogen bonding.
System and method for reducing combustion dynamics in a combustor (2023)

A system for reducing combustion dynamics in a combustor includes an end cap that extends radially across the combustor and includes an upstream surface axially separated from a downstream surface. A combustion chamber is downstream of the end cap, and tubes extend from the upstream surface through the downstream surface. Each tube provides fluid communication through the end cap to the combustion chamber. The system further includes means for reducing combustion dynamics in the combustor. A method for reducing combustion dynamics in a combustor includes flowing a working fluid through tubes that extend axially through an end cap that extends radially across the combustor and obstructing at least a portion of the working fluid flowing through a first set of the tubes.
Predicting TAVI paravalvular regurgitation outcomes based on numerical simulation of the aortic annulus eccentricity and perivalvular areas (2021)

Trans-catheter aortic valve implantation (TAVI) is an increasingly adopted technique which provides a minimal invasive solution for patients who suffer from severe aortic stenosis. Some complications of the procedure could be annular rupture or paravalvular leakage, both related with adverse outcome. In TAVI with balloon expandable devices, a mismatch between those two factors leads to a conflict situation, where improving one worsens the other. The presented research proposes a methodology that uses numerical simulation to obtain certain TAVI outcomes related with aortic regurgitation due to paravalvular leakage, such as perivalvular area, aortic eccentricity or annular pressure. The application of the methodology for two patients shows the possibility of predicting those quantities. The highest stress values are distributed along the contact area. Results also show that a great deformation on the aortic annulus does not necessarily imply a higher stress; pressure can either be converted into root reshape or into root stretching. Validation of the results was done using scientific publications, clinical guidelines and clinical reports. Numerical simulation provides a suitable tool that could possibly contribute to optimize the planification procedure adjusting the mismatch between size and pressure.
ChemInform Abstract: Electrostatic Control of the Molecular and Crystal Structure of an Olefinic Double Betaine (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Fission-Fragment Transport Effects as Related to Fission-Electric-Cell Efficiencies (1966)

An analysis of a parallel-plate UO2-fueled Fission Electric Cell is developed that includes a detailed treatment of the fission-fragment initial-energy spectrum, energy-charge loss during slowing, and energy dependence of the total range. The treatment of fragment transport is based, as much as possible, on correlations of experimental data. However, available data are skimpy, and several discrepancies, e.g., between available differential and integral energy-loss data, are noted.The importance of an accurate fragment transport model is demonstrated by the differences in efficiencies obtained from this detailed treatment, as opposed to earlier calculations that used simpler models, e.g., relative differences between models of as much as 15 and 80% are attributed to the treatment of the fragment charge and energy loss, respectively. The calculations are also shown to be fairly sensitive to the total-range-mass correlation, but only weakly dependent on the choice of the initial fragment charge.While efficiencies for the parallel-plate cell with reasonable fuel-layer thickness are found to range from 2 to 10%, efficiencies for cylindrical or spherical geometry may be 5 to 6 times this, and the concept may be competitive for certain specialized applications.
On a game problem involving systems with time delay (1973)

A dynamic programming approach is used to obtain feedback solutions to a game problem involving linear systems having a time delay. As is known, the optimal feedback gains in linear time delay systems with quadratic criterion are determined by partial differential equations [1]. In the particular case studied here, the solution to these equations can be obtained by first separating variables and then solving the resulting simpler equations. The optimal feedback control also has the advantage that it can be realized on-line.
Low-Loss Random Fiber Gratings Made With an fs-IR Laser for Distributed Fiber Sensing (2019)

By using the plane-by-plane grating inscription method with an fs-IR laser, random fiber gratings with low laser-induced loss were fabricated in SMF-28 fiber for distributed temperature sensing. Compared to conventional random gratings having broadband backscattering enhancement, the demonstrated random fiber grating has a well defined narrower bandwidth of backscattering enhancement, higher laser-induced backscattering level, and lower laser-induced loss, which are critical for long-haul distributed fiber sensor systems with high measurement accuracy. Experimental results showed that by using fabricated random fiber gratings along with the technique of optical frequency-domain reflectometry, a distributed temperature fiber sensor could be realized having a gauge length of 10 mm, standard deviation of temperature measurement as low as 0.00085 °C, and laser-induced loss of 0.08 dB/m.