gebhart/patrepeval huggingface dataset:
In vitro platform of allogeneic stem cell-derived cardiomyocyte transplantation for cardiac conduction defects (2018)

Using an in vitro experimental system to mimic cardiac conduction defect, transplanted allogeneic riPSC-CMs showed electrical coupling between two discrete regions of NRVMs. Electrophysiological testing using our platform will enable electrophysiological screening prior to transplantation of stem cell-derived CMs.
Generation and Consolidation of Recollections for Efficient Deep Lifelong Learning (2017)

Deep lifelong learning systems need to efficiently manage resources to scale to large numbers of experiences and non-stationary goals. In this paper, we explore the relationship between lossy compression and the resource constrained lifelong learning problem of function transferability. We demonstrate that lossy episodic experience storage can enable efficient function transferability between different architectures and algorithms at a fraction of the storage cost of lossless storage. This is achieved by introducing a generative knowledge distillation strategy that does not store any full training examples. As an important extension of this idea, we show that lossy recollections stabilize deep networks much better than lossless sampling in resource constrained settings of lifelong learning while avoiding catastrophic forgetting. For this setting, we propose a novel dual purpose recollection buffer used to both stabilize the recollection generator itself and an accompanying reasoning model.
More Signal, Less Noise: Single-primer Adenylation Method (SAM) for the Efficient Preparation of DNA for Transposon Sequencing (TnSeq) (2014)

ABSTRACT Transposon Sequencing (TnSeq) is a cutting-edge tool that allows quantitative, genome-wide genetic analysis of a given population in an experimental condition. TnSeq utilises next generation sequencing that is designed to perform optimally when all of the input material is of interest, therefore TnSeq is inefficient since only a small portion of nucleic acid fragments contain the transposon target site for primer annealing. We describe an innovative modification to standard transposon library preparation protocols that provides a significant improvement to the quality of sequencing data recovered.
A Practical, Hybrid Model for Predicting the Trajectories of Near-Surface Ocean Drifters (2004)

A hybrid Lagrangian-Eulerian model for calculating the trajectories of near-surface drifters in the ocean is developed in this study. The model employs climatological, near-surface currents computed from a spline fit of all available drifter velocities observed in the Pacific Ocean between 1988 and 1996. It also incorporates contemporaneous wind fields calculated by either the U.S. Navy [the Navy Operational Global Atmospheric Prediction System (NOGAPS)] or the European Centre for Medium-Range Weather Forecasts (ECMWF). The model was applied to 30 drifters launched in the tropical Pacific Ocean in three clusters during 1990, 1993, and 1994. For 10-day-long trajectories the forecasts computed by the hybrid model are up to 164% closer to the observed trajectories compared to the trajectories obtained by advecting the drifters with the climatological currents only. The best-fitting trajectories are computed with ECMWF fields that have a temporal resolution of 6 h. The average improvement over all 30 drifters of the hybrid model trajectories relative to advection by the climatological currents is 21%, but in the open-ocean clusters (1990 and 1993) the improvement is 42% with ECMWF winds (34% with NOGAPS winds). This difference between the open-ocean and coastal clusters is due to the fact that the model does not presently include the effect of horizontal boundaries (coastlines). For zero initial velocities the trajectories generated by the hybrid model are significantly more accurate than advection by the mean currents on time scales of 5-15 days. For 3-day-long trajectories significant improvement is achieved if the drifter's initial velocity is known, in which case the model-generated trajectories are about 2 times closer to observations than persistence. The model's success in providing more accurate trajectories indicates that drifters' motion can deviate significantly from the climatological current and that the instantaneous winds are more relevant to their trajectories than the mean surface currents. It also demonstrates the importance of an accurate initial velocity, especially for short trajectories on the order of 1-3 days. A possible interpretation of these results is that winds affect drifter motion more than the water velocity since drifters do not obey continuity.
ChemInform Abstract: Supercritical Carbon Dioxide as a Green Reaction Medium for Catalysis (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A fully integrated 77GHz FMCW radar transmitter using a fractional-N frequency synthesizer (2009)

A single chip transmitter for automotive FMCW radar application is implemented in 0.18um SiGe BiCMOS technology.
Crosstalk-Managed Heterogeneous Single-Mode 32-Core Fibre (2016)

A heterogeneous single-mode 32-core fibre with a cladding diameter of 243 micrometer is designed and fabricated. The highest core count in single-mode multi-core fibres and low worst-case crosstalk of less than -24 dB/1000 km in C-band are achieved simultaneously.
MINIMALLY INVASIVE PERCUTANEOUS TREATMENT OF FRACTURES OF THE UPPER HUMERUS: TECHNIQUE AND PRELIMINARY RESULTS (2002)

Purpose: Several techniques have been described for the treatment of unstable fractures of the upper humerus. None appear to be appropriate for subtuberosity fractures, associated or not with a fracture of the trochiter or impacted valgus cephalotuberosity fractures, allowing a stable fixation with anatomic reduction while preserving blood supply to the bone fragments. For the last year, we have studied prospectively a percutaneous minimally invasive technique for this type of fracture. Our preliminary results are analysed here. Material and methods: We used this technique for 12 patients aged 30 to 87 years with five displaced subtuberosity fractures, six subtuberosity fractures with a trochiter fracture and one impacted valgus cephalotuberosity fracture. Excepting the cephalotuberosity fracture, the joint fragment of the head was reduced by external manipulation under image amplifier guidance. Fixation was achieved with two 25/10 threaded pins inserted percutaneously in retrograde fashio from the anterolateral cortical to the humeral shaft. For eight cases, a third pin was inserted percutaneously from the trochiter to the medial cortical of the humerus. When percutaneous reduction of the trochiter was impossible (three cases) and for the cephalotuberosity fracture, we used a minimal transdeltoid lateral incision to reduce the trochiter and achieve reduction. Results: Reduction was very satisfactory in all cases. There was one superficial infection that required pin withdrawal at three weeks leading to the only secondary displacement that was minimal and tolerable. We removed the pins after a mean two months. There were no nonunions. Seven patients have a follow-up greater than six months and exhibited a Constant score of 87% (71% to 100%). Discussion: This techniques has provided very satisfactory results for rapid and stable fixation of the cephalic fragment without loss of blood supply and with a material easy to remove. Conclusion: These early results are very encouraging and incite us to pursue this technique and analyse long-term results.
Use of computerized tomography (CT) as an early prognostic indicator of response to imatinib mesylate (IM) in patients with gastrointestinal stromal tumors (GIST) (2004)

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CANDY: Enabling coherent DRAM caches for multi-node systems (2016)

This paper investigates the use of DRAM caches for multi-node systems. Current systems architect the DRAM cache as Memory-Side Cache (MSC), restricting the DRAM cache to cache only the local data, and relying on only the small on-die caches for the remote data. As MSC keeps only the local data, it is implicitly coherent and obviates the need of any coherence support. Unfortunately, as accessing the data in the remote node incurs a significant inter-node network latency, MSC suffers from such latency overhead on every on-die cache miss to the remote data. A desirable alternative is to allow the DRAM cache to cache both the local and the remote data. However, as data blocks can be cached in multiple DRAM caches, this design requires coherence support for DRAM caches to ensure correctness, and is termed Coherent DRAM Cache (CDC). We identify two key challenges in architecting giga-scale CDC. First, the coherence directory can be as large as few tens of MB. Second, cache misses to the read-write shared data in CDC cause longer delay due to the need to access the DRAM cache. To address both problems, this paper proposes CANDY, a low-cost and scalable solution that consists of two techniques for these challenges. First, CANDY places the coherence directory in 3D DRAM to avoid SRAM storage overhead, and re-purposes the existing on-die coherence directory as a DRAM-cache Coherence Buffer to cache recently accessed directory entries. Second, we propose Sharing-Aware Bypass, which dynamically detects the read-write shared data at run-time and enforces such data to bypass the DRAM cache. Our experiment on a 4-node system with 1GB DRAM cache per node shows that CANDY outperforms MSC by 25%, while incurring a negligible overhead of 8KB per node. CANDY is within 5% of an impractical system that has a 64MB SRAM directory per node, and zero cache latency to access the read-write shared data.
Data-Efficient Process Monitoring and Failure Detection for Robust Robotic Screwdriving (2019)

Screwdriving is one of the most prevalent assembly methods, yet its full automation is still challenging, especially for small screws. A critical reason is that existing techniques perform poorly in process monitoring and failure prediction. In addition, most solutions are essentially data-driven, thereby requiring lots of training data and laborious labeling. Moreover, they are not robust against varying environment conditions and suffer from generalization issues. To this end, we propose a stage and result prediction framework that combines knowledge-based process models with a hidden Markov model. The novelty of this work is the incorporation of operation-invariant characteristics such as screwdriving mechanics and stage transition graph, enabling our system to generalize across different experimental settings and largely reduce the required data and labeling. In our experiments, a system trained on M1.4x4 screws adapted with very little non-labeled data to three other screws (M1.2x3, M2.5x5, and M1.4x4) with widely varying tightening current, motor velocity, insertion force, and tightening force.
The incorporation effect of thin Al2O3 layers on ZrO2-Al2O3 nanolaminates in the composite oxide-high-K-oxide stack for the floating gate flash memory devices (2006)

2006 International Conference on Solid State Devices and Materials,The incorporation effect of thin Al2O3 layers on ZrO2-Al2O3 nanolaminates in the composite oxide-high-K-oxide stack for the floating gate flash memory devices
Propagation of spontaneous electrical activity in the ex vivo human uterus (2020)

Contractions of the non-pregnant uterus play a key role in fertility. Yet, the electrophysiology underlying these contractions is poorly understood. In this paper, we investigate the presence of uterine electrical activity and characterize its propagation in unstimulated ex vivo human uteri. Multichannel electrohysterographic measurements were performed in five freshly resected human uteri starting immediately after hysterectomy. Using an electrode grid externally and an electrode array internally, measurements were performed up to 24 h after hysterectomy and compared with control. Up to 2 h after hysterectomy, we measured biopotentials in all included uteri. The median root mean squared (RMS) values of the external measurements ranged between 3.95 μV (interquartile range (IQR) 2.41-14.18 μV) and 39.4 μV (interquartile range (IQR) 10.84-105.64 μV) and were all significantly higher than control (median RMS of 1.69 μV, IQR 1.13-3.11 μV), consisting of chicken breast meat. The RMS values decreased significantly over time. After 24 h, the median RMS (1.27 μV, IQR 0.86-3.04 μV) was comparable with the control (1.69 μV, IQR 1.13-3.11 μV, p = 0.125). The internal measurements showed a comparable pattern over time, but overall lower amplitude. The measured biopotentials propagated over the uterine surface, following both a plane-wave as well as an erratic pattern. No clear pacemaker location nor a preferred propagation direction could be identified. These results show that ex vivo uteri can spontaneously generate propagating biopotentials and provide novel insight contributing to improving our understanding of the electrophysiology of the human non-pregnant uterus.
Kinematics and dynamics of motion control based on acceleration control (2008)

Abstract The first IEYuzuruernational Workshop on Advanced Motion Control held in 1990 pointed out the importance of physical interpretation of motion control. The software servoing technology is now common in machine tools, robotics, and mechatronics. It has been intensively developed for the numerical control (NC) machines. Recently, motion control in an unknown environment will be more and more important. Conventional motion control is not always suitable due to the lack of adaptive capability to the environment. A more sophisticated ability in motion control is necessary for compliant contact with the environment. Acceleration control is the key technology of motion control in an unknown environment. The acceleration control can make a motion system a zero control stiffness system without losing robustness. Furthermore, a realization of multi‐degree‐of‐freedom motion is necessary for future human assistance. Motion for human assistant will require various control stiffness corresponding to the task. The review paper focuses on the modal coordinate system to integrate various control stiffness in the virtual axes. A bilateral teleoperation is a good candidate to consider for the future human assistant motion and integration of decentralized systems. Thus, the paper reviews and discusses the bilateral teleoperation from the control stiffness and the modal control design points of view. © 2008 Wiley Periodicals, Inc. Electron Comm Jpn, 91(6): 12– 22, 2008; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/ecj.10117
A Highly Regioselective Preparation of 4‐Chloromethyl‐5‐methyl‐2‐aryl‐1,3‐oxazoles (2004)

Abstract A facile highly regioselective process is described for the formation of 4‐chloromethyl‐1,3‐oxazoles from 1,3‐oxazole N ‐oxide/HCl salts. An explanation is presented for the high regioselectivity in deoxygenation‐chlorination using POCl 3 with HCl salts compared to the corresponding free N ‐oxides. The method is quite general and the products are isolated by direct precipitation in all cases studied.
Group-Wised Reference Signal Allocation for Single-Carrier FDMA Radio Access in Evolved UTRA Uplink (2007)

This paper proposes a group-wised reference signal (RS) for channel quality indicator measurement in frequency domain channel-dependent scheduling employing adaptive control of the transmission bandwidth in the single-carrier frequency division multiple access-based evolved UMTS terrestrial radio access uplink. In the proposed method, fluctuation in the interference power imparted to the surrounding cells is suppressed to a low level, and both the user throughput for a user equipment (UE) near the cell edge and the cell throughput are improved compared to the conventional uniform RS allocation due to reductions in the error when selecting the optimum UE in channel-dependent scheduling and selecting the modulation and coding scheme in the adaptive modulation and channel coding. Simulation results show that the user throughput at the 5% cumulative distribution function value when employing the proposed group-wised sounding RS allocation with the adaptive transmission bandwidth is increased by approximately 75% and 65% for the inter-site distance of 500 and 1732 m, respectively, compared to that using a uniform RS allocation, while achieving almost the same level of cell throughput.
Web Search Engines: Part 2 (2006)

This article reviews the algorithms and data structures required to index 400 terabytes of Web page text and deliver high-quality results in response to hundreds of millions of queries each day
Euro Banknote Recognition System Using a Three - layered Perceptron and RBF Networks (2003)

We propose an Euro banknote recognition system using two types of neural networks; a three-layered perceptron and a Radial Basis Function (RBF) network. A three-layered perceptron is well known method for pattern recognition and is also a very effective tool for classifing banknotes. An RBF network has a potential to reject invalid data because it estimates the probability distribution of the sample data. We use a three-layered perceptron for classification and several RBF networks for validation. The proposed system has two advantages over the system using only one RBF network. The feature extraction area can be simply defined, and the calculation cost does not increase when the number of classes increases. We also propose to use infra-red (IR) and visible images as input data to the system since Euro banknotes have quite significant features in IR images. We have tested our system in terms of acceptance rates for valid banknotes and rejection rates for invalid data.
HIV-1-Specific T Cell-Dependent Natural Killer (NK) Cell Activation: Major Contribution by NK Cells to Interferon-γ Production in Response to HIV-1 Antigens (2009)

Natural killer (NK) cells can directly recognize virus-infected cells.Here, we demonstrate that NK cells also produce interferon (IFN)-g in an HIV-1-specific, T cell-dependent manner.After stimulation of peripheral blood mononuclear cells (PBMCs) from HIV-1-infected individuals with HIV-1-derived peptides, up to half of the IFNg-producing PBMCs are NK cells.These results indicate that T cell-dependent NK cell IFN-g production can be important for immune control of HIV-1, and have implications for the interpretation of data from vaccine trials using ELISPOT and ELISA.
Phosphinylhydrazyls R2NN(.cntdot.)P(O)L2, an ESR study. Influence of the captodative effect on the three-electron NN .pi. bond (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhosphinylhydrazyls R2NN(.cntdot.)P(O)L2, an ESR study. Influence of the captodative effect on the three-electron NN .pi. bondM. Negareche, Badrudin, Y. Berchadsky, A. Friedmann, and P. TordoCite this: J. Org. Chem. 1986, 51, 3, 342–346Publication Date (Print):February 1, 1986Publication History Published online1 May 2002Published inissue 1 February 1986https://pubs.acs.org/doi/10.1021/jo00353a013https://doi.org/10.1021/jo00353a013research-articleACS PublicationsRequest reuse permissionsArticle Views106Altmetric-Citations7LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Use of atypical antipsychotics in mood disorders. (2001)

Cumulative data indicate that atypical antipsychotics can serve as adjunctive as well as alternative agents in the treatment of drug-resistant mood disorders. Olanzapine and risperidone add-on treatment was found to be effective for major depression with psychotic features and good results were achieved with currently available atypical antipsychotics (clozapine, risperidone, olanzapine, quetiapine and ziprasidone) in reducing symptoms of acute mania, especially when added to mood stabilizers. The role of atypical antipsychotics in maintenance and prophylactic treatment is not yet clear. Although there are differences in the side effect profiles of the various atypical antipsychotics, their use is limited by adverse effects such as extrapyramidal symptoms, weight gain, somnolence and sexual dysfunction.
Introduction (2020)

This introduction gives a glimpse of the content available in the chapters that follow. One of the chapters draws upon the open systems notions of boids to document the informal settlements and human life of Caracas. Another discusses and documents through various types of drawing of what they term the ‘practical-social space’ of a Chinese village. Yet another chapter explores or moves beyond the limits of designerly and academic documentation through their account of the social-spatial experiences of refugees arriving in Berlin through a series of events and performances where the refugees and other locals play an active role. An anthropologist who works with architects and architectural design educators, produces a manifesto for Actor-Network Theory. The author of this book has since the early-1990s been experimenting with what landscape architectural urbanism might be: with a distinct focus on the social, through what is called as ‘landscape assemblages.
SiGe HBTs with ${f_{T}/f_{\max}\,\sim\,375/510GHz}$ Integrated in 45nm PDSOI CMOS (2021)

A 45nm BiCMOS process, based on PDSOI CMOS, with SiGe HBT NPNs having <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">${f_{T}f_{\max}\,=\,375/510GHz}$</tex> is presented. The bipolars are integrated on a PDSOI wafer in an epitaxial region above the handle wafer to avoid self-heating concerns. To our knowledge, this is the first time a high performance SiGe BiCMOS process has been demonstrated on a PDSOI wafer. In addition to the HBTs, the technology features high performance NFETs with <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">${f_{T}f_{MAX}\,=\,265/330GHz}$</tex> and PFETs with <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">${f_{T}f_{MAX}\,=\,250/340GHz}$</tex> enabling flexibility in circuit design. A full-flow demonstration PDK, digital standard cell and IO cell libraries have been released for experimental circuit design work. This work, funded under the DARPA T-MUSIC program, will address future extensions to higher HBT performance and more-advanced CMOS nodes.
Incognito: the secret lives of the brain (2011)

*Why does your foot hit the brake pedal before you are conscious of danger ahead? *Why do you hear your name is mentioned in a conversation that you didn't think you were listening to? *Why is a person whose name begins with J more likely to marry another person whose name begins with J? *Why is it so difficult to keep a secret? *And how is it possible to get angry at yourself: who, exactly, is mad at whom? A thrilling subsurface exploration of the mind and all its contradictions. A NEW YORK TIMES BESTSELLER