gebhart/patrepeval huggingface dataset:
Electron-Transfer Reorganization Energies of Isolated Organic Molecules (2002)

He I photoelectron spectra of phenanthrene (1), 1,10-phenanthroline (2), phenazine (3), dibenzo[a,c]anthracene (4), dibenzo[a,c]phenazine (5), and dipyrido[3,2-a;2‘3‘-c]phenazine (6) have been obtained. Assignment of the π ionization states was aided by electronic structure calculations: the first ionization state of 1, 2B1(π1), is observed at 7.888 ± 0.002 eV, 2B2(π1) of 2 is at 8.342 ± 0.002 eV, and 2B1g(π1) of 3 is at 8.314 ± 0.002 eV. Spectra of 4−6 are reported for the first time: 2A2(π1) of 4 is at 7.376 ± 0.002 eV, and both 5 (7.983 ± 0.002 eV) and 6 (8.289 ± 0.002 eV) exhibit quasi-degenerate first and second ionization states. Quantum-mechanical reorganization energies, λQM, were extracted from analyses of vibrational structure: values are 149 ± 5 (1), 167 ± 5 (2), 68 ± 2 (3), and 92 ± 4 (4) meV. Low-frequency modes were treated semiclassically: values of λSC are estimated to be 21 ± 1 (1), 13 ± 1 (2), 22 ± 1 (3), 66 ± 1 (4), 27 ± 9 (5), and 16 ± 1 (6) meV. Reorganization energies (λ = λQM + λSC) of isolated molecules are 170 ± 5 (1), 180 ± 5 (2), 90 ± 2 (3), and 158 ± 4 (4) meV. Density functional calculations (B3LYP/6-311G++(d,p)) give λ values that are on average 63 meV lower than experimentally derived energies.
Structure of Multiresponsive Brush-Decorated Nanoparticles: A Combined Electrokinetic, DLS, and SANS Study (2015)

Particles consisting of a glassy poly(methyl methacrylate) core (ca. 40 nm in radius) decorated with a poly(N-isopropylacrylamide) anionic corona are synthesized using either methacrylic acid (MA) or acrylic acid (AA) as reactive comonomers in the shell. The different reactivity ratios of MA and AA toward N-isopropylacrylamide originates p(MA-N) and p(N-AA) particles with carboxylate charges supposedly located, preferentially, in the close vicinity of the core and at the shell periphery, respectively. The corresponding swelling features of these nanoparticles are addressed over a broad range of pH values (4 to 7.5), NaNO3 concentrations (3 to 200 mM), and temperatures (15 to 45 °C) by dynamic light scattering (DLS) and small angle neutron scattering (SANS). DLS shows that the swelling of the particle shells increases their thickness from ∼10 to 90 nm with decreasing temperature, ionic strength, or increasing pH, with the effect being more pronounced for p(N-AA) whose lower critical solution temperature is shifted to higher values compared to that of p(MA-N). Potentiometric titration and electrokinetic results further reflect the easier dissociation of carboxyl groups in p(N-AA) and a marked heterogeneous interfacial swelling of the latter with decreasing solution salt content. The DLS response of both particles is attributed to the multiresponsive nature of a peripheral dilute shell, while SANS only probes the presence of a quasi-solvent-free dense polymer layer, condensed on the core surface. The thickness of that layer slightly increases from ∼6 to 9.5 nm with increasing temperature from 15 to 45 °C (at 15 mM NaNO3 and pH 5) due to the collapse of the outer dilute shell layer. Overall, results evidence a nonideal brush behavior of p(MA-N) and p(N-AA) and their microphase segregated shell structure, which supports some of the conclusions recently formulated from approximate self-consistent mean-field computations.
Superconductivity competing with the incommensurate antiferromagnetic insulating state in the organic conductor (MDT-TS)(AuI2)0.441 (2005)

The organic conductor (MDT-TS)${(\mathrm{Au}{\mathrm{I}}_{2})}_{0.441}$ undergoes a metal-insulator transition at ${T}_{\mathrm{MI}}=50\phantom{\rule{0.3em}{0ex}}\mathrm{K}$, where MDT-TS is $5H$-2-(1,3-diselenol-2-ylidene)-1,3,4,6-tetrathiapentalene. The static magnetic susceptibility demonstrates an antiferromagnetic ordering below this temperature. Hydrostatic pressure suppresses this insulating state, and a superconductivity appears at ${T}_{c}=3.2\phantom{\rule{0.3em}{0ex}}\mathrm{K}$ above $10.5\phantom{\rule{0.3em}{0ex}}\mathrm{kbar}$. The phase diagram demonstrates a transition from the incommensurate antiferromagnetic insulating state to a superconducting state in an organic conductor with a noninteger carrier number.
CCL21 overexpressed on lymphatic vessels drives thymic hyperplasia in myasthenia (2009)

We postulate that thymic overexpression of CCL21 on specialized lymphatic vessels results in abnormal peripheral lymphocyte recruitment, bringing naive B cells in contact with the inflammatory environment characteristic of MG thymuses, where they can be sensitized against AChR.
Diving into the Finestructure of Macroporous Polymer Foams Synthesized via Emulsion Templating: A Phase Diagram Study (2017)

During our studies on emulsion-templated monodisperse polymer foams we found significant differences in the finestructure if the locus of initiation is changed. This motivated us to study the phase behavior of the liquid template. Our studies indicate that the template consists of droplets of three different length scales: The water droplets generated via microfluidics (∼70 μm) are surrounded by a continuous phase in which a w/o emulsion (≤100 nm) coexists with a w/o microemulsion (∼5 nm). We speculate that the w/o-emulsion droplets act as seeds for the porous finestructure observed in AIBN-initiated polymer foams. We have experimental evidence that the w/o emulsion inverts to an o/w emulsion with progressing polymerization. This explains the granular texture observed in KPS-initiated polymer foams. The control of the finestructure is important in the preparation of tailor-made polymer foams because it directly impacts the material's density and thus, in turn, its mechanical stability.
Immunogenicity and protective efficacy of SARS-CoV-2 mRNA vaccine encoding secreted non-stabilized spike in female mice (2023)

Establishment of an mRNA vaccine platform in low- and middle-income countries (LMICs) is important to enhance vaccine accessibility and ensure future pandemic preparedness. Here, we describe the preclinical studies of "ChulaCov19", a SARS-CoV-2 mRNA encoding prefusion-unstabilized ectodomain spike protein encapsulated in lipid nanoparticles (LNP). In female BALB/c mice, ChulaCov19 at 0.2, 1, 10, and 30 μg elicits robust neutralizing antibody (NAb) and T cell responses in a dose-dependent relationship. The geometric mean titers (GMTs) of NAb against wild-type (WT, Wuhan-Hu1) virus are 1,280, 11,762, 54,047, and 62,084, respectively. Higher doses induce better cross-NAb against Delta (B.1.617.2) and Omicron (BA.1 and BA.4/5) variants. This elicited immunogenicity is significantly higher than those induced by homologous CoronaVac or AZD1222 vaccination. In a heterologous prime-boost study, ChulaCov19 booster dose generates a 7-fold increase of NAb against Wuhan-Hu1 WT virus and also significantly increases NAb response against Omicron (BA.1 and BA.4/5) when compared to homologous CoronaVac or AZD1222 vaccination. Challenge studies show that ChulaCov19 protects human-ACE-2-expressing female mice from COVID-19 symptoms, prevents viremia and significantly reduces tissue viral load. Moreover, anamnestic NAb response is undetectable in challenge animals. ChulaCov19 is therefore a promising mRNA vaccine candidate either as a primary or boost vaccination and has entered clinical development.
A call admission control scheme in ATM networks (2002)

In an ATM (asynchronous transfer mode) network, call admission control decides whether or not to accept a new call, so as to ensure the service quality of both individual existing calls and of the new call itself. The measure of service quality used for the call admission control considered here is virtual cell loss probability, PV. PV may be formulated simply from the maximum and the average cell rates alone, and it provides a good estimate of cell loss probability without respect to the burst lengths. PV computational complexity increases rapidly with an increase either in the number of call types, K, or in the number of existing calls of individual call types; and for this reason, the author proposes a method for calculating a PV approximation on the upper side, with the aim of achieving real-time call admission control. Its complexity of computation is a linear order of K. Also proposed is a call admission algorithm which utilizes this approximation method and for which, in some cases, the computational complexity is independent of K.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Mining Documentation to Extract Hyperparameter Schemas (2020)

AI automation tools need machine-readable hyperparameter schemas to define their search spaces. At the same time, AI libraries often come with good human-readable documentation. While such documentation contains most of the necessary information, it is unfortunately not ready to consume by tools. This paper describes how to automatically mine Python docstrings in AI libraries to extract JSON Schemas for their hyperparameters. We evaluate our approach on 119 transformers and estimators from three different libraries and find that it is effective at extracting machine-readable schemas. Our vision is to reduce the burden to manually create and maintain such schemas for AI automation tools and broaden the reach of automation to larger libraries and richer schemas.
Boosting In Planta Production of Antigens Derived from the Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) and Subsequent Evaluation of Their Immunogenicity (2014)

Porcine reproductive and respiratory syndrome (PRRS) is a disease of swine, caused by an arterivirus, the PRRS virus (PRRSV). This virus infects pigs worldwide and causes huge economic losses. Due to genetic drift, current vaccines are losing their power. Adaptable vaccines could provide a solution to this problem. This study aims at producing in planta a set of antigens derived from the PRRSV glycoproteins (GPs) to be included in a subunit vaccine. We selected the GP3, GP4 and GP5 and optimized these for production in an Arabidopsis seed platform by removing transmembrane domains (Tm) and/or adding stabilizing protein domains, such as the green fluorescent protein (GFP) and immunoglobulin (IgG) 'Fragment crystallizable' (Fc) chains. Accumulation of the GPs with and without Tm was low, reaching no more than 0.10% of total soluble protein (TSP) in homozygous seed. However, addition of stabilizing domains boosted accumulation up to a maximum of 2.74% of TSP when GFP was used, and albeit less effectively, also the Fc chains of the porcine IgG3 and murine IgG2a increased antigen accumulation, to 0.96% and 1.81% of TSP respectively, while the murine IgG3 Fc chain did not. Antigens with Tm were less susceptible to these manipulations to increase yield. All antigens were produced in the endoplasmic reticulum and accordingly, they carried high-mannose N-glycans. The immunogenicity of several of those antigens was assessed and we show that vaccination with purified antigens did elicit the production of antibodies with virus neutralizing activity in mice but not in pigs.
Manganic oxidations of 3-substituted toluenes (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTManganic oxidations of 3-substituted toluenesAlain Chaintreau, Guy Adrian, and Daniel CouturierCite this: J. Org. Chem. 1981, 46, 22, 4562–4564Publication Date (Print):October 1, 1981Publication History Published online1 May 2002Published inissue 1 October 1981https://doi.org/10.1021/jo00335a048RIGHTS & PERMISSIONSArticle Views255Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (397 KB) Get e-Alerts Get e-Alerts
Submilliampere lasing of Zn-diffused mesa buried-hetero Al x Ga 1- x As/GaAs multi-quantum-well lasers at 77 K (1986)

Extremely low-threshold semiconductor lasers were fabricated by forming Zn-diffused mesa buried-hetero (DMB) structures from low-pressure MOCVD-grown AlxGa1-xAs/GaAs multi-quantum-well, separate-confinement heterostructure wafers. CW threshold currents as low as 880 μA at 77 K and 2.4 mA at room temperature were obtained for a 100 μm-long device.
<title>Sub-millisecond phase contrast wavefront sensor based on an optically addressed ferroelectric liquid crystal spatial light modulator</title> (2002)

A sub-millisecond wavefront sensor based on a non-linear Zernike filter is described. The sensor's key element is an optically addressed spatial light modulator (OASLM). The OASLM is composed of ferroelectric liquid crystal and an amorphous silicon carbide photo-conducting film. The OASLM is placed into the focal plane of a Fourier filtering system. The sensor operates with circularly polarized input light. For the high intensity (zero order) spectral component the deviation of the ferroelectric liquid crystal director by (pi) /4 (45 degree(s)) results in a (pi) /2 phase shift. This provides wavefront phase distortion visualization similar to a conventional Zernike filter. The registered characteristic response time of the sensor is near 0.2 ms for light intensity on the order of 100 nW.
Squared Coherence Analysis Might Suggest Cerebral Autoregulation Post-Surgery Impairment in Patients Undergoing Surgical Aortic Valve Replacement (2022)

A squared coherence (K2) approach was applied to investigate cerebral autoregulation (CA) in 33 patients (age: 63±14 yrs; 27 males) undergoing surgical aortic valve replacement (SAVR) before surgery (PRE), after surgery (POST) and after a 3-month follow-up (POST3). K2 was assessed between mean arterial pressure and mean cerebral blood flow velocity in very low frequency (VLF, 0.02-0.07 Hz), low frequency (LF, 0.07-0.15 Hz) and high frequency (HF, 0.15-0.4 Hz) bands at rest in supine position (REST) and during active standing (STAND). The significance of K2 was tested individually via a surrogate approach. Results showed that K2 in HF band increased during POST compared to PRE at REST but this rise was more limited during STAND. Analysis of K2 suggests a possible impairment of CA after SAVR that might expose patients to a higher risk of developing post-surgery cerebrovascular adverse events.
Introduction and Overview (2010)

Abstract The standard approach to argument structure has many empirical deficiencies, is not general enough to incorporate well-known descriptive generalizations, and, furthermore, fails to take into account languages in which argument structure is expressed via grammatical function changing morphology on the verbal root. This book proposes a radically different approach to argument structure whereby functional categories merge in bottom-to-top fashion with a predicate or with the output of previous Merge operations in conjunction with a fixed Universal Order of Merge. The approach involves three primary argument types—Agent, Theme, and Affectee—whose hierarchical structures are exactly the opposite of what is normally expected. There are also various kinds of secondary arguments, including Instrument, Benefactive, Source, and Goal.
Arenaviruses: Hemorrhagic Fevers (2012)

The family Arenaviridae contains at least 24 distinct viruses, grouped into two serocomplexes. The Old World arenaviruses Lassa and Lujo and the New World arenaviruses Chapare, Guanarito, Junín, Machupo, and Sabiá cause severe and often lethal viral hemorrhagic fever in humans. Each of these seven viruses is carried by subclinically infected rodents of different species, and the ecological distribution of these rodents also roughly defines the geographic occurence of arenaviral disease. Infections occur when humans come in direct or indirect contact with rodents, rodent tissues, or rodent excreta and secreta. Consequently, disease can be prevented if such contact is limited. There is currently no FDA-approved vaccine for the prevention of infection, and treatment of the disease is currently limited to the use of ribavirin
Performance of an Ideal Attenuation and Scatter Correction Strategy for a Next-Generation SPECT System Dedicated to Quantitative Clinical Brain Imaging (2019)

A next-generation, adaptive, multi-pinhole system, AdaptiSPECT-C, dedicated to SPECT brain imaging is currently under development in our research team. Attenuation and scatter correction have proven to be critical to enhance image quality and quantification for brain imaging. The motivation for this investigation was to determine the enhancement in image quality by adding scatter correction strategy in addition to attenuation correction for brain imaging with AdaptiSPECT-C. An ideal scatter correction strategy was investigated in this GATE simulation study using a brain perfusion phantom and compared to the reference case for which an air attenuation medium was considered. We demonstrated that the use of the attenuation and the ideal scatter correction strategy significantly enhanced the imaging performance of AdaptiSPECT-C in case of clinical <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">123</sup> I brain perfusion imaging. In addition, our study concluded that the use of an attenuation correction without compensating for scatter strongly degrades the contrast of the reconstruction, despite a quantitative improvement compared to the case for which no correction was used.
Diabetic kidney disease, a potentially serious issue resulting from collision of the coronavirus disease 2019 and diabetes global pandemics (2021)

Sciendo provides publishing services and solutions to academic and professional organizations and individual authors. We publish journals, books, conference proceedings and a variety of other publications.
American Society of Colon and Rectal Surgeons 91st Annual Convention Podium and Poster abstracts (1992)

American Society of Colon and Rectal Surgeons 91st Annual Convention Podium and Poster abstracts: PDF Only
A Highly Enantioselective Benzothiepine Synthesis (2000)

A highly enantioselective synthesis of benzothiepine 1a has been accomplished via an enantioenriched sulfoxide intermediate obtained by asymmetric oxidation with a chiral oxaziridine in 89:11 er. The key step is a thermodynamically controlled asymmetric cyclization reaction that produces two new stereogenic centers. The (4R,5R) isomer 1a was obtained in 98:2 er.
Association between Chemotherapy-Response Assays and Subsets of Tumor-Infiltrating Lymphocytes in Gastric Cancer: A Pilot Study (2015)

Cancer cell death rates in response to specific chemotherapeutic agents were not significantly associated with the distribution of TIL subsets.
Double-path erbium-doped fiber amplifier with enhanced noise figure characteristics (2000)

Summary form only given. Efforts paid to various pump schemes such as forward, backward and bidirectional pumping have made significant contributions to highly reliable erbium-doped fiber amplifiers (EDFAs) with high gain and low noise figure characteristics. Reflective type EDFAs by using a mirror and an optical isolator were proposed to achieve a better utilization of wasted pump energy. Therefore, this double-path EDFA doubled the gain coefficient compared to that of single-path ones. However, its noise figure was worse than that of single-path EDFAs. Using a 3 nm bandpass filter (BPF) between the EDF and mirror to remove the amplified spontaneous emission (ASE) improved the noise performance. However, the BPF scheme is not suitable for wavelength division multiplexing (WDM) optical communications since the BPF simultaneously filtered out other WDM signals outside its transmission band.
On the sensitivity of the H-infinity norm of interconnected systems with time-delays (2010)

We consider delay differential algebraic equations (DDAEs) to model interconnected systems with time-delays. The DDAE framework does not require any elimination techniques and can directly deal with any interconnection of systems and controllers with time-delays. In this framework, we analyze the properties of the H-infinity norm of interconnected systems with time-delays. We show that the standard H-infinity norm may be sensitive to arbitrarily small delay perturbations. We introduce the strong H-infinity norm which is insensitive to small delay perturbations and give its properties. We conclude that the strong H-infinity norm is more appropriate in any practical control application compared to the standard H-infinity norm for systems with time-delays.
Measurement of the ramp linearity of extremely linear frequency ramps using a fractional dual loop structure (2001)

A dual loop synthesizer concept based on fractional divider techniques for measuring highly linear analog frequency ramps is presented. Due to the excellent sensitivity of the measurement set-up, relative nonlinearities as low as 10/sup -9/ are ascertainable. The measurements obtained with a prototype circuit are shown. They illustrate the expected high sensitivity. Furthermore, a vector network analyzer (VNA) based on this dual loop synthesizer is described which allows for very fast measurements.
Edge-based BE-FE coupling for electromagnetics (2006)

Electromagnetic problems can be solved using the coupled boundary-element/finite-element (BE-FE) method, where the conducting and magnetic parts are discretized by finite elements and the surrounding space is described with the help of the boundary element method. In this paper, we propose a novel BE-FE coupling procedure for the solution of electromagnetic problems. Starting from the potential formulation we derive a representation formula in the BE domain in terms of differential forms. We discretize the corresponding boundary integral equation by the DeRham map which generalizes the classical point collocation and yields an alternative approach to the Galerkin BE method. The Cauchy data will be discretized by the first-order Whitney elements on the boundary. In the FE domain, we apply the Galerkin discretization scheme using the spatial first-order Whitney elements. The coupling of these methods will be described and the feasibility of the proposed method will be demonstrated by means of numerical examples
Loading dynamics of optical trap and parametric excitation resonances of trapped atoms (2006)

We study the loading dynamics of an optical dipole trap and an optical lattice both experimentally and theoretically. A simple power dependence for the number of trapped atoms (N∝P3∕2) is revealed in both cases. We then study the parametric excitation of the trapped atoms. High order parametric resonance is observed close to but lower than 4ν in a CO2 laser optical lattice. The existence of the high harmonic and its shift toward lower frequency are attributed to the anharmonicity of the optical trapping potential. We investigate the discrepancy between experimentally measured optical lattice frequencies and the theoretical calculation for several published experiments and present corrected formula for trap frequency calculations. Using this corrected formula and accounting for the off-center lattice sites, we present a modified formula for calculating the optical lattice frequency and obtain better agreement between experimental measurement and theoretical calculation.