gebhart/patrepeval huggingface dataset:
Evaluation of the IAGOS-Core GHG package H 2 O measurements during the DENCHAR airborne inter-comparison campaign in 2011 (2018)

Abstract. As part of the DENCHAR (Development and Evaluation of Novel Compact Hygrometer for Airborne Research) inter-comparison campaign in northern Germany in 2011, a commercial cavity ring-down spectroscopy (CRDS) based gas analyzer (G2401-m, Picarro Inc., US) was installed on a Learjet to measure atmospheric water vapor, CO2, CH4, and CO. The CRDS components were identical to those chosen for integration aboard commercial airliners within the IAGOS (In-service Aircraft for a Global Observing System) project. Since the quantitative capabilities of the CRDS water vapor measurements were never evaluated and reviewed in detail in a publication before, the campaign allowed for an initial assessment of the long-term IAGOS water vapor measurements by CRDS against reference instruments with a long performance record (Fast In-situ Stratospheric Hygrometer (FISH) and CR-2 frost point hygrometer (Buck Research Instruments L.L.C., US), both operated by Research Centre Jülich). For the initial water calibration of the instrument it was compared against a dew point mirror (Dewmet TDH, Michell Instruments Ltd., UK) in the range from 70 000 to 25 000 ppm water vapor mole fraction. During the inter-comparison campaign the analyzer was compared on the ground over the range from 2 to 600 ppm against the dew point hygrometer used for calibration of the FISH reference instrument. A new, independent calibration method based on the dilution effect of water vapor on CO2 was evaluated. Comparison of the in-flight data against the reference instruments showed that the analyzer is reliable and has a good long-term stability. The flight data suggest a conservative precision estimate for measurements made at 0.4 Hz (2.5 s measurement interval) of 4 ppm for H2O &lt; 10 ppm, 20 % or 10 ppm (whichever is smaller) for 10 ppm &lt; H2O &lt; 100 ppm, and 5 % or 30 ppm (whichever is smaller) for H2O &gt; 100 ppm. Accuracy of the CRDS instrument was estimated, based on laboratory calibrations, as 1 % for the water vapor range from 25 000 ppm down to 7000 ppm, increasing to 5 % at 50 ppm water vapor. Accuracy at water vapor mole fractions below 50 ppm was difficult to assess, as the reference systems suffered from lack of data availability.
Amperometric NO-recordings of individual OSNs of wild-type, OMP-GFP, or eNOS-deficient mutant mice. (2015)

&lt;p&gt;&lt;i&gt;A,&lt;/i&gt; Application of KCl (45 mM) induces a robust NO-signal in an isolated wild-type OSNs. &lt;i&gt;B,&lt;/i&gt; Veratridine (10 µM) induces a NO-signal in a wild-type OSN, but fails to induce NO release in an OSN of an eNOS-deficient mutant mouse (eNOS-delMu). &lt;i&gt;C,&lt;/i&gt; Stimulation of the olfactory signal transduction pathway with forskolin (20 µM) led to a clear NO-signal in OSNs of OMP-GFP mice. Signals could be prevented by pre-incubation with L-NAME (1 mM) or by performing the experiments in extracellular medium with low Ca&lt;sup&gt;2+&lt;/sup&gt;-concentration (1 nM). &lt;i&gt;D,&lt;/i&gt; Application of the odorants geraniol (200 µM) or octanal (500 µM) produced NO-signals in OMP-GFP mice. Arrows mark the application of the indicated stimulus. Large deflections of the signal at the time of application represented artefacts that occurred in some experiments (forskolin, geraniol). These artefacts were blanked for clarity.&lt;/p&gt;
The Src family kinase inhibitor, dasatinib, inhibits angiogenesis in vitro and in vivo (2008)

AACR Annual Meeting-- Apr 12-16, 2008; San Diego, CA

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Src family tyrosine kinases (SFKs) have essential roles in regulating multiple events involved in angiogenesis. We investigated the effects of dasatinib (BMS-354825), an orally bioavailable dual Src/Abl kinase inhibitor, on angiogenesis using both in vitro and in vivo models. Our results show that dasatinib inhibited VEGF- or bFGF-induced human endothelial cell (HUVEC) survival, migration and tube formation in vitro with IC50 values in the low nM range. Dasatinib-mediated HUVEC apoptosis was due to its ability to abrogate cell adhesion, consistent with a mechanism involving anoikis. These biological responses were associated with inhibition of the Src/FAK/p130CAS/paxillin signaling pathway following dasatinib treatment in the low nM range. Moreover, dasatinib was a potent inhibitor of ex vivo angiogenesis in a chick aortic ring assay. Using two-photon confocal microscopy, we examined the effect of dasatinib on tumor angiogenesis directly in vivo . Results show that dasatinib dramatically suppresses tumor angiogenesis in a human prostate cancer xenograft model. Taken together, these findings suggest that the anti-tumor activity of dasatinib may be at least partially due to its anti-angiogenic activity. This study also provides a rationale for clinical development of dasatinib as an anti-angiogenic therapeutic for cancer.
Structured Text Modification Using Guided Inference (2008)

Keywords: POP-I.C. end-user applications, POP-II.A. end-users, POP-IV.A. programming by example We describe a technique that allows end-users to specify automated transformations of structured text by inferring an underlying model. Inference is achieved with a novel algorithm, Structured Prediction by Partial Match (SPPM), a generalisation of the well-known PPM approach to predictive text entry and compression. We created two simple applications, as examples of &amp;quot;first steps &amp;quot; end-user programming tasks that can be achieved using SPPM. In empirical evaluations, each of these applications proved to be substantially superior to equivalent facilities in leading commercial products. 1.
Control of CO2 Adsorption and Desorption Using Polyethylene Glycol in a Tetraethylenepentamine Thin Film: An In Situ ATR and Theoretical Study (2016)

The reversible adsorption of CO2 on tetraethylenepentamine (TEPA) and the polyethylene glycol (PEG)-modified amine sites were investigated using attenuated total reflection infrared (ATR-IR) spectroscopy, mass spectrometry (MS), and density functional theory (DFT). The presence of PEG at the amine site increased the rate of formation of adsorbed CO2, enhanced the formation of weakly adsorbed CO2 which can be removed from flowing inert gas at room temperature, and decreased CO2 desorption peak (i.e., sorbent regeneration) temperature. The calculated CO2 binding energy (BE) and optimized structures suggest CO2 adsorbed on TEPA primarily in the form of ammonium carbamate. The presence of PEG promoted the formation of a species which exhibited an experimental IR spectrum resembling the simulated spectrum of a low BE zwitterion species. The observation suggests PEG controlled the formation of the adsorbed intermediate species. Modeling of the transient CO2 adsorption profiles further showed PEG accelerated the rate of diffusion of adsorbed CO2 species in TEPA film by decreasing viscosity. The IR spectra of TEPA-PEG revealed PEG could assist in breaking up hydrogen bonding between amine sites, further supporting the promotion of diffusion of adsorbed CO2 through decreasing TEPA viscosity. This study unravelled the mechanism of the effects of PEG on CO2 capture kinetics and capacity on amine sites.
Wrapping TVInterface forWatching Multiple Programs Efficiently (2007)

We developed aTV browseruser-interface called Wrapping Interface withclip andpaste mannersforwatching multiple programsefficiently. We studied operations basedon theconcept ofthewrapping interface anddeveloped several prototypes, andwediscussed additional ideas forenhancing the wrapping interface. I.INTRODUCTION Diversification ofbroadcast systems hasbrought about an explosion inthenumber ofviewable programs forconsumers. As large-capacity HDD andTV withmultiple tuners are becoming widely used, ourstyles forwatching programs are changing. Becauseofthestandard forconnecting home information appliances, various digital devices, suchasHDD recorders, TVs,andPCsareconnected witheachother through thenetwork. Inthis situation, viewers havealarge variety ofdigital contents fromwhichtochoose, butourtime tospend watching themislimited. Thus, auserinterface is required forbrowsing andwatching large digital contents appropriately andefficiently. Several approaches tooffer aTV browser user-interface havepreviously beentried. Ourteamhasdeveloped twoTV interfaces foraccessing arich variety ofcontents easily with theoption ofcontinuous recording ofmulti-channels.( 1)
JH‐4 reduces HMGB1‐mediated septic responses and improves survival rate in septic mice (2018)

Inhibition of high mobility group box 1 (HMGB1) and restoration of endothelial integrity are emerging as attractive therapeutic strategies for the management of severe vascular inflammatory diseases. Recently, we found that JH-4, a synthesized decursin derivative, exhibited a strong anti-Hutchinson-Gilford progeria syndrome by efficiently blocking progerin-lamin A/C binding. In this study, we examined the effects of JH-4 on HMGB1-mediated septic responses and the survival rate in a mouse sepsis model. The anti-inflammatory activities of JH-4 were monitored based on its effects on lipopolysaccharide- or cecal ligation and puncture (CLP)-mediated release of HMGB1. The antiseptic activities of JH-4 were determined by measuring permeability, leukocyte adhesion, migration, and the activation of proinflammatory proteins in HMGB1-activated human umbilical vein endothelial cells and mice. JH-4 inhibited the release of HMGB1 and downregulated HMGB1-dependent inflammatory responses in human endothelial cells. JH-4 also inhibited HMGB1-mediated hyperpermeability and leukocyte migration in mice. In addition, treatment with JH-4 reduced CLP-induced release of HMGB1, sepsis-related mortality, and pulmonary injury in vivo. Our results indicate that JH-4 is a possible therapeutic agent to treat various severe vascular inflammatory diseases via the inhibition of the HMGB1 signaling pathway.
Supplementary Figure 1 from Dual-specific Chimeric Antigen Receptor T Cells and an Indirect Vaccine Eradicate a Variety of Large Solid Tumors in an Immunocompetent, Self-antigen Setting (2023)

&lt;p&gt;Dual-specific T cells respond against both gp100 and Her2.&lt;/p&gt;
Challenges in Manufacturing Adenoviral Vectors for Global Vaccine Product Deployment (2014)

Abstract Once adenovirus vector-based vaccines are licensed for the prevention of important infectious diseases, manufacturing processes capable of reliably delivering large numbers of vaccine doses will be required. The highest burden of disease for many infectious pathogens under investigation occurs in resource-poor settings. Therefore, the price per dose will be an important determinant of success. This review describes common practices for manufacturing replication-incompetent adenovirus vectors at clinical scale. Recent innovations and strategies aimed at improving the cost-effectiveness of manufacturing and ensuring high-volume vaccine production and purification are described. Hereto, technologies to increase bioreactor yields are reviewed. In addition, the use of single-use perfusion bioreactors, modification of some purification steps to avoid the use of expensive endonucleases, and use of charged filters during anion exchange all have the potential to bring down the cost of goods and are thus described. Finally, processes for ensuring quality throughout the manufacturing process, methods for testing viral identity, and safety of master seeds through to the end vaccine product are described.
VVENC UND VVDEC: FRAUNHOFER HHI STELLT OFFENE, OPTIMIERTE IMPLEMENTIERUNGEN DES NEUEN VIDEOKODIERSTANDARDS H.266/VVC BEREIT (2021)

Komprimierte Videodaten machen heute den mit Abstand grosten Anteil an Bits im Internet sowie im mobilen Datenverkehr aus. Dabei ist die Tendenz weiter steigend. Im Juli 2020 wurde der neue Videokodierstandard Versatile Video Coding (H.266/VVC) verabschiedet. H.266/VVC wurde gemeinsam von ITU-T und ISO/IEC entwickelt und soll helfen, alle zukunftigen Herausforderungen im Bereich der Videoubertragung zu meistern.
ChemInform Abstract: Catalytic Enantioselective 5‐Hydroxyisoxazolidine Synthesis: An Asymmetric Entry to β‐Amino Acids. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Characterization of strain relaxation in low-defect-density thin single and step-graded germanium buffer layers by high-resolution two-dimensional x-ray diffraction mapping (2000)

International audience
ThirdLight (2017)

We present a low-cost 3D tracking system for virtual reality, gesture modeling, and robot manipulation applications which require fast and precise localization of headsets, data gloves, props, or controllers. Our system removes the need for cameras or projectors for sensing, and instead uses cheap LEDs and printed masks for illumination, and low-cost photosensitive markers. The illumination device transmits a spatiotemporal pattern as a series of binary Gray-code patterns. Multiple illumination devices can be combined to localize each marker in 3D at high speed (333Hz). Our method has strengths in accuracy, speed, cost, ambient performance, large working space (1m-5m) and robustness to noise compared with conventional techniques. We compare with a state-of-the-art instrumented glove and vision-based systems to demonstrate the accuracy, scalability, and robustness of our approach. We propose a fast and accurate method for hand gesture modeling using an inverse kinematics approach with the six photosensitive markers. We additionally propose a passive markers system and demonstrate various interaction scenarios as practical applications.
Characterization of Au-based Catalysts Using Novel Cerium Oxide Supports (2007)

Extended abstract of a paper presented at Microscopy and Microanalysis 2007 in Ft. Lauderdale, Florida, USA, August 5 – August 9, 2007
2,6-Diketopiperazines from Amino Acids, from Solution-Phase to Solid-Phase Organic Synthesis (2001)

A method to prepare 1,3-disubstituted 2,6-diketopiperazines (2,6-DKP) as useful heterocyclic library scaffolds in the search of new leads for drug discovery is described. The method can be used in solution-phase and solid-phase conditions. In the key step of the synthesis, the imido portion of the new molecule is formed in solution through intramolecular cyclization, under basic conditions, of a secondary amide nitrogen on a benzyl ester. A Wang resin carboxylic ester is used as the acylating agent under solid-phase conditions, allowing the cyclization to take place with simultaneous cleavage of the product from the resin ("cyclocleavage"). The synthetic method worked well with several couples of amino acids, independently from their configuration, and was used for the parallel synthesis of a series of fully characterized compounds. The use of iterative conditions in the solid phase (repeated addition of fresh solvent and potassium carbonate to the resin after filtering out the product-containing solution) allowed us to keep diastereoisomer content below the detection limit by HPLC and (1)H NMR (200 MHz).
An experimental investigation of thermal stress relief in two steels (1995)

Thermal relief of residual stresses was studied in AISI 4340 alloy steel (38 HRC) and AISI 1070 spring steel (45 HRC). Residual Stresses in simple strip-geometry specimens introduced by shot peening, abusive grinding, and mechanical bending were measured by X-ray diffraction before and after thermal treatments for varying times over the temperature range of 375 F to 1,050 F. Results correlated well with a time-temperature parameter having the same form as the Larson-Miller parameter commonly used to correlate creep deformation and stress-rupture behavior of metallic materials. Thermal stress relief results exhibited not only a material dependence, but also an apparent dependence on the initial magnitude of residual stress before thermal treatment and, possibly, on the manner of their creation.
Cluster-based analysis of 3D MIMO channel measurement in an urban environment (2015)

Massive MIMO (multiple - input - multiple - output) and full-dimensional MIMO systems in next-generation cellular communications systems as well as high-data-rate military systems have garnered considerable attention recently. For the assessment of their performance, knowledge of the 3D propagation channel characteristics, i.e., azimuth and elevation of the multipath components (MPCs) is essential. In this paper, we present first results of a 3D outdoor propagation channel measurement campaign performed in an urban macro-cellular environment. The measurements were performed with a 20 MHz wideband polarimetric MIMO channel sounder centered at 2.53 GHz. At each measurement location, parameters of all MPCs observed were extracted with RIMAX, an iterative maximum likelihood high-resolution algorithm. It was observed that MPCs naturally grouped into clusters. We then present a cluster-based analysis of the propagation channel providing some results of the intra and inter cluster parameters and their relevant statistics. Correlation between all extracted cluster parameters are also provided. Parameters such as elevation and azimuth spread (at the base-station) in this work have been used as input to recent international channel model standardization.
Basic biology, taxonomy and genetics (1998)

1. Morphology and Identification of Trichoderma W.Gams and J. Bisset 2. Molecular Taxonomy of Trichoderma and Gliocladium and their Teleomorphs E. Lieckfeldt, K. Kuhls and S. Muthumeenakshi 3. Ecology of Trichoderma D. Klein and D. Eveleigh 4. Sporulation and Light-Induced Development in Trichoderma V. Betina and V. Farkas 5. Nutrition, Cellular Structure and Basic Metabolic Pathways in Trichoderma and Gliocladium E. Kubicek-Pranz 6. Protein Secretion and Glycosylation in Trichoderma
Metal Atoms and Particles on Oxide Supports:  Probing Structure and Charge by Infrared Spectroscopy (2001)

Supported metal particles may exhibit properties fundamentally different from the corresponding bulk materials. To gain insight into principles underlying size- and structure-dependent phenomena, a structural characterization of small aggregates at the atomic level is crucial, while far from straightforward. A long-standing question in the study of supported clusters and metal-oxide interfaces concerns the extent of metal-oxide charge transfer. We show that infrared spectroscopy, utilizing carbon monoxide as a probe molecule, may provide valuable information on both structure and charge of ultrasmall metal aggregates and single metal atoms. To create supported particles containing only few atoms or even a single atom, submonolayer amounts of the transition metals palladium, rhodium, and iridium were vapor-deposited onto a thin, well-ordered alumina film at low substrate temperatures. Scanning tunneling microscopy served to characterize nucleation behavior and average particle size. Sharp, discrete features in the infrared spectra of adsorbed CO are due to uniform metal (M) carbonyls, most notably the mono- and dicarbonyl species MCO and M(CO)2. The thermal behavior of such carbonyls is reflected in the thermal evolution of their infrared signatures. Comparing the C−O stretching frequencies of MCO species on the aluminum oxide film to those of their matrix-isolated neutral and charged counterparts, the charge of the metal centers is estimated. In this way, the extent of metal-oxide charge transfer at point defects and regular sites of the alumina film is shown to be smaller than ±0.2 elementary charges. By contrast, Rh atoms more strongly bound to oxide line defects are oxidized by the alumina substrate.
Local Structure-Driven Localized Surface Plasmon Absorption and Enhanced Photoluminescence in ZnO-Au Thin Films (2016)

International audience
Linear phase-and-frequency-modulated photonic links using optical discriminators (2012)

We report our experimental results for linear analog optical links that use phase or frequency modulation and optical discrimination. The discriminators are based on two architectures: a cascaded MZI FIR lattice filter and a ring assisted MZI (RAMZI) IIR filter. For both types of discriminators, we demonstrate > 6 dB improvement in the link's third-order output intercept point (OIP3) over a MZM link. We show that the links have low second-order distortion when using balanced detection. Using high optical power, we demonstrate an OIP3 of 39.2 dBm. We also demonstrate 4.3dB improvement in signal compression.
A Flexible Resource Management Architecture for the Blue Gene/P Supercomputer (2007)

Blue Genereg/P are a massively parallel supercomputer intended as the successor to Blue Gene/L. It leverages much of the existing architecture of its predecessor to provide scalability up to a petaflop of peak computing power. The resource management software for such a large parallel system faces several challenges, including system fragmentation due to partitioning, presenting resource usage information using a polling or event driven model, and acting as a barrier between external resource management systems and the Blue Gene/P core. This paper describes how the Blue Gene/P resource management architecture is extremely flexible by providing multiple methodologies for obtaining resource usage information to make scheduling decisions. Three distinctly separate resource management services can be described. First, the Bridge API, a full-featured API suitable for fine tuning scheduling and allocation decisions. Second, a light-weight allocator API for allocating resources without substantial development costs. And lastly, configuring the system into static partitions. Job scheduling strategies utilizing each of the methods can be discussed.
A 40-Gb/s QSFP Optoelectronic Transceiver in a 0.13&#x003BC;m CMOS Silicon-on-Insulator Technology (2008)

We have demonstrated a 40-Gb/s optoelectronic transceiver in a quad small form-factor pluggable (QSFP) module. Each module includes a 4x10-Gb/s, 0.13 μm CMOS silicon-on-insulator integrated optoelectronic transceiver chip co-packaged with a single, externally modulated CW laser.
DiCE (2019)

In stereoscopic displays, such as those used in VR/AR headsets, our eyes are presented with two different views. The disparity between the views is typically used to convey depth cues, but it could be also used to enhance image appearance. We devise a novel technique that takes advantage of binocular fusion to boost perceived local contrast and visual quality of images. Since the technique is based on fixed tone curves, it has negligible computational cost and it is well suited for real-time applications, such as VR rendering. To control the trade-off between contrast gain and binocular rivalry, we conduct a series of experiments to explain the factors that dominate rivalry perception in a dichoptic presentation where two images of different contrasts are displayed. With this new finding, we can effectively enhance contrast and control rivalry in mono- and stereoscopic images, and in VR rendering, as confirmed in validation experiments.