gebhart/patrepeval huggingface dataset:
New approach for aggregating multi‐sensory data (1993)

Abstract The task of sensory data fusion may involve the aggregation of sensory measurements that may be from different phenomenological domains and that, in many cases, could embrace some conflicting information cues. It is rather a challenge to find suitable strategies by which measurements obtained by the different sensors of the system can be aggregated so that a consistent interpretation of these measurements is achieved. In this article, we present a novel approach to achieve this goal. A recursive group utility function that is capable of bringing the group of sensors into consensus is used. After each sensor in the group gathers information relevant to the sensory task, the group engages in what we call the uncertainty estimation stage. This is an information theorybased process that allows each sensor to assess its self‐uncertainty and the conditional uncertainties of other sensors. This process facilitates the computation of a weighting scheme that operates recursively on sensor observations until the group reaches a consensus. Whenever new observations are made, the uncertainty estimates of sensors are updated and used to compute a new weighting scheme. To demonstrate the efficacy and to show how the methodology works, the article discusses how the method can be used to tackle the multi‐sensor object identification problem. © 1993 John Wiley &amp; Sons, Inc.
Structure of Anionic Poly(2-phenylbutadiene) (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure of Anionic Poly(2-phenylbutadiene)R. J. Ambrose and W. L. HergenrotherCite this: Macromolecules 1972, 5, 3, 275–279Publication Date (Print):May 1, 1972Publication History Published online1 May 2002Published inissue 1 May 1972https://pubs.acs.org/doi/10.1021/ma60027a009https://doi.org/10.1021/ma60027a009research-articleACS PublicationsRequest reuse permissionsArticle Views140Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
An Arabidopsis heat shock protein complements a thermotolerance defect in yeast. (1994)

The heat shock protein Hsp104 of the yeast Saccharomyces cerevisiae plays a key role in promoting survival at extreme temperatures. We found that when diverse higher plant species are exposed to high temperatures they accumulate proteins that are antigenically related to Hsp104. We isolated a cDNA corresponding to one of these proteins from Arabidopsis. The protein, AtHSP101, is 43% identical to yeast Hsp104. DNA gel blot analysis indicated that AtHSP101 is encoded by a single- or low-copy number gene. AtHsp101 mRNA was undetectable in the absence of stress but accumulated to high levels during exposure to high temperatures. When AtHSP101 was expressed in yeast, it complemented the thermotolerance defect caused by a deletion of the HSP104 gene. The ability of AtHSP101 to protect yeast from severe heat stress strongly suggests that this HSP plays an important role in thermotolerance in higher plants.
Time-Saving Benefits of Intravital Staining (2008)

One of the challenges in labeling tissues for fluorescence microscopy is minimizing sample processing while maintaining or improving the information generated by the fluorescent label. Generally, tissues are extracted, fixed, and embedded in mounting media (such as paraffin), sectioned, and then postprocessed by removing the paraffin, blocking, labeling, and washing. Despite all of these steps, the consistency of labeling quality can vary as a result of several factors, including heterogeneity in labeling efficiency from slide to slide, the necessity of postprocessing to obtain information on sequential sections of tissue, interference from the mounting media, and loss of native three-dimensional structural information, especially in thicker sections. A method for embedding and processing tissues that have been labeled by intravital staining is described in this study. Intravital staining is the process in which live-cell dyes and other labels are injected into the bloodstream before fixation of the tissues. Tissues processed this way can be imaged upon sectioning without further staining and retain their native, three-dimensional information, thereby improving the information retained by the labels and speeding up sample processing.
Optically induced spin wave dynamics in [Co/Pd]8 antidot lattices with perpendicular magnetic anisotropy (2014)

We present an all-optical time-resolved measurement of spin wave (SW) dynamics in a series of antidot lattices based on [Co(0.75 nm)/Pd(0.9 nm)]8 multilayer (ML) systems with perpendicular magnetic anisotropy. The spectra depend significantly on the areal density of the antidots. The observed SW modes are qualitatively reproduced by the plane wave method. The interesting results found in our measurements and calculations at small lattice constants can be attributed to the increase of areal density of the shells with modified magnetic properties probably due to distortion of the regular ML structure by the Ga ion bombardment and to increased coupling between localized modes. We propose and discuss the possible mechanisms for this coupling including exchange interaction, tunnelling, and dipolar interactions.
Performances of endoscopic holography with a multicore optical fiber (1995)

A holographic setup that involves the use of a multicore optical fiber as an in situ recording medium has been developed. The hologram is transmitted to a CCD camera for electronic processing, and the image is reconstructed numerically, providing more flexibility to the holographic process. The performances of this imaging system have been evaluated in terms of the resolution limit and robustness relative to noise. The experimental cutoff frequency has been measured experimentally over a range of observation distances (4-10 mm) and presents a very good agreement with the predictions made by simulation. The system features a resolution of 5-µm objects for a 4-mm observation distance. The different sources of noise have been analyzed, and their influence on resolution has been proved to be nonrelevant.
Purity (2015)

Although flash storage has largely replaced hard disks in consumer class devices, enterprise workloads pose unique challenges that have slowed adoption of flash in ``performance tier'' storage appliances. In this paper, we describe Purity, the foundation of Pure Storage's Flash Arrays, the first all-flash enterprise storage system to support compression, deduplication, and high-availability.
Development of security functions for a medical information sharing platform (2007)

Abstract It is considered important in the medical care sector to share medical information such as case information. There have been positive moves toward electronic storage and sharing of various data. There have been many studies of systems to realize such services, but the usual approach is to construct a network system of client–server type with concentrated information management at one site. In contrast, we are promoting the development of a medical information sharing platform in which information distributed among peers (hospitals) is shared. The P2P configuration has the advantage that the processing load is distributed and a relatively low‐cost system can be created. The keys to creating this platform include the development of a secure information sharing mechanism, and also an efficient retrieval mechanism. This paper presents a security mechanism which was constructed for verification experiments on such a platform. In the design of the security mechanism, the above characteristics of the platform are considered, and an attempt is made to provide content in a practical processing time. The implemented security mechanism is evaluated assuming the processing loads that occur in actual operation, and its effectiveness is demonstrated. © 2007 Wiley Periodicals, Inc. Syst Comp Jpn, 38(11): 49–63, 2007; Published online in Wiley InterScience ( www.interscience.wiley.com ). DOI 10.1002/scj.20466
SON for LTE-WLAN access network selection: design and performance (2016)

Mobile network operators (MNOs) are deploying carrier-grade Wireless Local Area Network (WLAN) as an important complementary system to cellular networks. Access network selection (ANS) between cellular and WLAN is an essential component to improve network performance and user quality-of-service (QoS) via controlled loading of these systems. In emerging heterogeneous networks characterized by different cell sizes and diverse WLAN deployments, automatic tuning of the network selection functionality plays a crucial role. In this article, we present two distinct Self-Organizing Network (SON) schemes for tuning the ANS between the Long-Term Evolution (LTE) and WLAN systems. The SON functions differ in terms of availability of inter-system information exchange and internal algorithm design for traffic load control. System level simulations in a site-specific dense urban network show that the proposed schemes improve significantly the user quality of service (QoS), and network capacity over the reference scheme when offloading to WLAN is performed simply based on signal coverage.
Type III adenylyl cyclase localizes to primary cilia throughout the adult mouse brain (2007)

Solitary primary cilia project from nearly every cell type in the human body. These organelles are considered to have important sensory and signaling functions. Although primary cilia have been detected throughout the mammalian brain, their functions are unknown. The study of primary cilia in the brain is constrained by the scarcity of specific markers for these organelles. We previously demonstrated that type III adenylyl cyclase (ACIII) is a marker for primary cilia on neonatal hippocampal neurons in vivo and in vitro. We further showed that ACIII localizes to cilia on cultured glial cells. Here, we report that ACIII is a marker for primary cilia throughout many regions of the adult mouse brain. Furthermore, we report that ACIII localizes to primary cilia on choroid plexus cells and some astrocytes in the brain, which to our knowledge is the first report of a marker for visualizing cilia on glia in vivo. Overall, our data indicate that ACIII is a prominent marker of primary cilia in the brain and will provide an important tool to facilitate further investigations into the functions of these organelles.
A Novel Depletion-IMOS (DIMOS) Device With Improved Reliability and Reduced Operating Voltage (2008)

We experimentally demonstrate a novel depletion-IMOS (DIMOS) device with a 12.1-mV/dec subthreshold slope and 5-decade ON/OFF ratio, employing a depletion mode of operation instead of inversion. DIMOS structure improves reliability by reducing hot carrier injection and features 40% lower breakdown voltages with higher ON currents compared to conventional IMOS.
Effects of light quality on the accumulation of oil in a mixed culture of Chlorella sp. and Saccharomyces cerevisiae (2011)

Abstract BACKGROUND: Chlorella strains rather than terrestrial oil crops having higher oil content and shorter generation time have been considered as promising candidates for alternative biodiesel. Since the influence of light quality on oil formation of microalgae in either monoculture or mixed culture has been shown to be either inconsistent or ambiguous, a light‐emitting diode (LED) photo‐bioreactor with different light sources and intensities was used in this study to investigate a cost‐effective lipid production process. RESULTS: The oil accumulation in a mixed culture of Chlorella sp. and Saccharomyces cerevisiae was higher than that in the monoculture under the different light sources used. Results of the influence of light quality on the mixed culture indicated that the optimal light wavelength and intensity for biomass formation was red LED light at 1000 lux, whereas the optimum for oil formation was blue LED light at 1000 lux. A novel two‐stage LED photo‐bioreactor was thus proposed and the highest P max and productivity in this study were obtained as 261 mg L −1 and 8.16 mg L −1 h −1 , respectively. CONCLUSION: A novel two‐stage LED photo‐bioreactor using a mixed culture to optimize microalgal oil production was proposed and successfully demonstrated in this study. Copyright © 2011 Society of Chemical Industry
Medical Signal-Conditioning and Data-Interface System (2006)

A general-purpose portable, wearable electronic signal-conditioning and data-interface system is being developed for medical applications. The system can acquire multiple physiological signals (e.g., electrocardiographic, electroencephalographic, and electromyographic signals) from sensors on the wearer s body, digitize those signals that are received in analog form, preprocess the resulting data, and transmit the data to one or more remote location(s) via a radiocommunication link and/or the Internet. The system includes a computer running data-object-oriented software that can be programmed to configure the system to accept almost any analog or digital input signals from medical devices. The computing hardware and software implement a general-purpose data-routing-and-encapsulation architecture that supports tagging of input data and routing the data in a standardized way through the Internet and other modern packet-switching networks to one or more computer(s) for review by physicians. The architecture supports multiple-site buffering of data for redundancy and reliability, and supports both real-time and slower-than-real-time collection, routing, and viewing of signal data. Routing and viewing stations support insertion of automated analysis routines to aid in encoding, analysis, viewing, and diagnosis.
Detection of Alzheimer’s disease-related neuroinflammation by a PET ligand selective for glial versus vascular translocator protein (2021)

A substantial and constitutive expression of translocator protein (TSPO) in cerebral blood vessels hampers the sensitive detection of neuroinflammation characterized by greatly induced TSPO expression in activated glia. Here, we conducted in vivo positron emission tomography (PET) and in vitro autoradiographic imaging of normal and TSPO-deficient mouse brains to compare the binding properties of <sup>18</sup>F-FEBMP, a relatively novel TSPO radioligand developed for human studies based on its insensitivity to a common polymorphism, with <sup>11</sup>C-PK11195, as well as other commonly used TSPO radioligands including <sup>11</sup>C-PBR28, <sup>11</sup>C-Ac5216 and <sup>18</sup>F-FEDAA1106. TSPO in cerebral vessels of normal mice was found to provide a major binding site for <sup>11</sup>C-PK11195, <sup>11</sup>C-PBR28 and <sup>18</sup>F-FEDAA1106, in contrast to no overt specific binding of <sup>18</sup>F-FEBMP and <sup>11</sup>C-Ac5216 to this vascular component. In addition, <sup>18</sup>F-FEBMP yielded PET images of microglial TSPO with a higher contrast than <sup>11</sup>C-PK11195 in a tau transgenic mouse modeling Alzheimer's disease (AD) and allied neurodegenerative tauopathies. Moreover, TSPO expression examined by immunoblotting was significantly increased in AD brains compared with healthy controls, and was well correlated with the autoradiographic binding of <sup>18</sup>F-FEBMP but not <sup>11</sup>C-PK11195. Our findings support the potential advantage of comparatively glial TSPO-selective radioligands such as <sup>18</sup>F-FEBMP for PET imaging of inflammatory glial cells.
Investigation of a Delayed Feedback Controller of MEMS Resonators (2013)

Controlling mechanical systems is an important branch of mechanical engineering. Several techniques have been used to control Microelectromechanical systems (MEMS) resonators. In this paper, we study the effect of a delayed feedback controller on stabilizing MEMS resonators. A delayed feedback velocity controller is implemented through modifying the parallel plate electrostatic force used to excite the resonator into motion. A nonlinear single degree of freedom model is used to simulate the resonator response. Long time integration is used first. Then, a finite deference technique to capture periodic motion combined with the Floquet theory is used to capture the stable and unstable periodic responses. We show that applying a suitable positive gain can stabilize the MEMS resonator near or inside the instability dynamic pull in band. We also study the stability of the resonator by tracking its basins of attraction while sweeping the controller gain and the frequency of excitations. For positive delayed gains, we notice significant enhancement in the safe area of the basins of attraction.
Anti-KIAA0513 Antibody as a Broad-spectrum Biomarker of Mortal Atherosclerotic and Cancerous Diseases (2021)

Abstract Background: Numerous antibody biomarkers have been reported for cancer and atherosclerosis-related diseases. The major complications of atherosclerosis and diabetes mellitus (DM) are acute ischemic stroke (AIS), cardiovascular disease (CVD), and chronic kidney disease (CKD). Cancer development is accompanied by arterial disorders such as angiogenesis and atherosclerosis, and DM is a risk factor for certain cancers. Atherosclerosis-related diseases and cancers are therefore interrelated and could be detected by a common biomarker. Methods: We employed the protein array method for the initial screening of antigens and employed the amplified luminescent proximity homogeneous assay-linked immunosorbent assay (AlphaLISA) to evaluate antibody levels in serum samples. Results: The protein array identified KIAA0513 as an antigen recognized by serum IgG antibodies in the sera of patients with atherosclerosis. We then prepared recombinant glutathione S-transferase-fused KIAA0513 protein. AlphaLISA showed significantly higher serum antibody levels against KIAA0513 protein in patients with AIS, transient ischemic attack, DM, CVD, obstructive sleep apnea syndrome (OSAS), CKD, and solid cancers, such as esophageal, gastric, colon, lung, and breast cancer, than in healthy donors. A receiver operating characteristic (ROC) analysis revealed that the highest areas under the ROC curves of anti-KIAA0513 antibodies were for esophageal cancer, nephrosclerosis-type CKD, and DM. Spearman’s correlation analysis revealed that serum anti-KIAA0513 antibody levels were associated with maximum intima-media thickness and plaque score, which are indices of atherosclerosis and stenosis. Conclusion: Serum anti-KIAA0513 antibody markers appear to be useful for diagnosing AIS, TIA, DM, CVD, OSAS, CKD, and solid cancers and might reflect common arterial alterations leading to atherosclerotic and cancerous diseases.
Accurate Inference with Inaccurate RRAM Devices: Statistical Data, Model Transfer, and On-line Adaptation (2020)

Resistive random-access memory (RRAM) is a promising technology for in-memory computing with high storage density, fast inference, and good compatibility with CMOS. However, the mapping of a pre-trained deep neural network (DNN) model on RRAM suffers from realistic device issues, especially the variation and quantization error, resulting in a significant reduction in inference accuracy. In this work, we first extract these statistical properties from 65 nm RRAM data on 300mm wafers. The RRAM data present 10-levels in quantization and 50% variance, resulting in an accuracy drop to 31.76% and 10.49% for MNIST and CIFAR-10 datasets, respectively. Based on the experimental data, we propose a combination of machine learning algorithms and on-line adaptation to recover the accuracy with the minimum overhead. The recipe first applies Knowledge Distillation (KD) to transfer an ideal model into a student model with statistical variations and 10 levels. Furthermore, an on-line sparse adaptation (OSA) method is applied to the DNN model mapped on to the RRAM array. Using importance sampling, OSA adds a small SRAM array that is sparsely connected to the main RRAM array; only this SRAM array is updated to recover the accuracy. As demonstrated on MNIST and CIFAR-10 datasets, a 7.86% area cost is sufficient to achieve baseline accuracy for the 65 nm RRAM devices.
Supplementary video from Extracellular Vesicles from High-Grade Glioma Exchange Diverse Pro-oncogenic Signals That Maintain Intratumoral Heterogeneity (2023)

&lt;p&gt;M and P GSCs display distinct intra-spherical organization in vitro. Representative time lapse movie&lt;/p&gt;
Altered antigenicity of M‐177, a 177‐kDa allergen from the house dust mite Dermatophagoides farinae, in stored extract (1998)

M-177 is a protease-sensitive allergen. The breakdown products of M-177 provoked higher allergenic activity than the intact allergen.
Associations Between Depression and Anxiety Symptoms and Retinal Vessel Caliber in Adolescents and Young Adults (2014)

Depression and anxiety symptoms are associated with measurable signs in the retinal microvasculature in early life, suggesting that pathological microvascular mechanisms linking depression/anxiety and cardiovascular disease may be operative from a young age.
Electronic and Ionic Dynamics Coupled at Solid–Liquid Electrolyte Interfaces in Porous Nanocomposites of Carbon Black, Poly(vinylidene fluoride), and γ-Alumina (2017)

Better fundamental understanding of the transport properties within nanocomposite materials consisting of interpenetrated percolating networks and used as electrodes is needed to improve their performance for a variety of devices. The simultaneous measurement of their effective ionic and electronic conductivities requires a sophisticated experimental set up. Here, the reciprocal influence of ionic and electronic transfers at different scales of model porous nanocomposites made of carbon black–poly(vinylidene fluoride)−γ alumina wetted by a nonaqueous electrolyte is investigated by broadband dielectric spectroscopy (BDS) from 40 to 1010 Hz, between 223 and 293 K. Experimental results show that the coupling of electronic and ionic dynamics at interfaces in the nanostructured composite material results in significant decrease of the electronic conductivity compared to the dry state and increase of the ionic conductivity compared to the bulk electrolyte.
Analysis of cytomegalovirus infection and replication in acinar epithelial cells of the rat lacrimal gland. (1996)

The herpesvirus RCMV invades and replicates in acinar epithelial cells from the rat lacrimal gland. The magnitude of the viral infection may be significantly influenced by gender and alterations in the hormonal environment.
Qualitative study on the price of drugs for multiple sclerosis (2019)

Contrary to prevailing narratives that underscore drug development costs, findings from our interviews suggest that the existing price ecosystem, overall corporate growth, international pricing disparities, and supply chain-related distortions may play a more central role in drug pricing decision.