gebhart/patrepeval huggingface dataset:
Characterization and optimization of liquid electrodes for lateral dielectrophoresis (2007)

Using the concept of insulator-based "electrodeless" dielectrophoresis, we present a novel geometry for shaping electric fields to achieve lateral deviation of particles in liquid flows. The field is generated by lateral planar metal electrodes and is guided along access channels to the active area in the main channel. The equipotential surfaces at the apertures of the access channels behave as vertical "liquid" electrodes injecting the current into the main channel. The field between a pair of adjacent liquid electrodes generates the lateral dielectrophoretic force necessary for particle manipulation. We use this force for high-speed deviation of particles. By adding a second pair of liquid electrodes, we focus a particle stream. The position of the focused stream can be swept across the channel by adjusting the ratio of the voltages applied to the two pairs. Based on conformal mapping, we provide an analytical model for estimating the potential at the liquid electrodes and the field distribution in the main channel. We show that the simulated particle trajectories agree with observations. Finally, we show that the model can be used to optimize the device geometry in different applications.
Engineering cell shape and function through control of substrate adhesion (2023)

Recognition of the importance of cell adhesion for control of cell function has led to the development of novel techniques for fabricating bioactive substrates. Recent studies demonstrate that these culture substrata can modulate cell form, growth, and production of specialized products, independently of soluble serum components or defined growth factors. These new methods for engineering cell shape and function may be extremely useful for applications in biotechnology, such as drug screening, in vitro toxicology, genetic engineering, bioprocessing, and tissue engineering.
Polycrystalline Si optimization for 45nm node Ni-FUSI gate (2006)

In this paper, the authors report the impact of polycrystalline Si structure on the NMOS transistor performance with a HfSiON/Ni-FUSI (fully silicided) gate. For polycrystalline films, as deposited grain structure was predominantly columnar at heater temperatures 690-730degC, except in the presence of hydrogen where the grains assume a random microcrystalline structure. Amorphous film was achieved by lowering the heater temperature down to 610C. The impact of the deposition temperature and adding H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> during the deposition on the poly-Si film structure and surface roughness is investigated. Ni-FUSI gate electrode was fabricated with these different structures. The resulting NMOS transistor performance is discussed
Multivariate Analysis of Job Pause Time Data Using Classification and Regression Tree and Kernel Clustering (2013)

Abstract The well treatment program is an important part of the field development plan, and certain variables, such as job pause time (JPT), can affect its efficiency. JPT is the time during which pumping is paused between subsequent treatments of a job. The objectives of this work are to investigate whether, from existing data, it is possible to find patterns in significant variables that affect the extreme values of JPT in a particular region. The answers are sought by applying a classification and regression tree (CART) to both categorical and continuous variables in the database. The practical application of CART is presented using case studies first using classical CART analysis, then using CART analysis with enhancement tools such as the normal score transform (NST), and then dividing the large dataset into smaller groups using clustering. Significant variables are found that affect the response variables, and predictor variables are ranked in order of their importance. Such information can be used to control predictor variables that cause high JPT. The results are outlined in an intuitive way, including categorical, continuous, and missing values. Because CART is a data driven, deterministic model, we cannot calculate the confidence interval of the predicted response. Confidence in the results is purely based on the historical values, and the accuracy of the result produced by a tree model depends on the quality of the recorded data measured in terms of volume, reliability, and consistency. The prediction capability of CART is enhanced by the use of NST and clustering techniques. The approach presented in this paper analyzes a dataset with limited information and high uncertainty and should lead to developing a method for generating proxy models to find future success indices (e.g., for drilling efficiency or production from a fracture). This could standardize stimulation and generate decision ‘best practices’ to save costs in field development and the optimization process.
Global DNA hypomethylation is associated with in utero exposure to cotinine and perfluorinated alkyl compounds (2010)

Environmental exposures in-utero may alter the epigenome, thus impacting chromosomal stability and gene expression. We hypothesized that in utero exposures to maternal smoking and perfluoroalkyl compounds (PFCs) are associated with global DNA hypomethylation in umbilical cord serum. Our objective was to determine if global DNA methylation could be used as a biomarker of in utero exposures to maternal smoking and PFCs. Using an ELISA-based method, global DNA methylation was quantified in umbilical cord serum from 30 newborns with high (> 10 ng/ml, mean 123.8 ng/ml), low (range 1-10 ng/ml, mean 1.6 ng/ml) and very low (< 1 ng/ml, mean 0.06 ng/ml) cord serum cotinine levels. Y chromosome analysis was performed to rule out maternal DNA cross-contamination. Cord serum global DNA methylation showed an inverse dose response to serum cotinine levels (p< 0.001). Global DNA methylation levels in cord blood were the lowest among newborns with smoking mothers (mean=15.04%; 95% CI, 8.4, 21.7) when compared to babies of mothers who were second-hand smokers (21.1%; 95% CI, 16.6, 25.5) and non-smokers (mean=29.2%; 95% CI, 20.1, 38.1). Global DNA methylation was inversely correlated with serum PFOA (r= -0.72, p < 0.01) but not PFOS levels. Serum Y chromosome analyses did not detect maternal DNA cross-contamination. This study supports the use of global DNA methylation status as a biomarker of in utero exposure to cigarette smoke and PFCs.
Synthesis of metal complexes with macrocyclic ligands having prescribed patterns of unsaturation. Oxidative dehydrogenation of fused-ring systems involving charged, delocalized six-membered chelate rings (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of metal complexes with macrocyclic ligands having prescribed patterns of unsaturation. Oxidative dehydrogenation of fused-ring systems involving charged, delocalized six-membered chelate ringsChristian J. Hipp, Leonard F. Lindoy, and Daryle H. BuschCite this: Inorg. Chem. 1972, 11, 9, 1988–1994Publication Date (Print):September 1, 1972Publication History Published online1 May 2002Published inissue 1 September 1972https://pubs.acs.org/doi/10.1021/ic50115a002https://doi.org/10.1021/ic50115a002research-articleACS PublicationsRequest reuse permissionsArticle Views146Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Genetic epidemiology, parallel algorithms, and workstation networks (2002)

Many interesting problems in genetic epidemiology are formulated as non-linear optimization problems using the Gemini/Almini library of routines. Because of the wide availability of networked workstations, we investigate cost-effectively improving the performance of the Gemini/Almini library by exploiting parallelism with a set of workstations connected via a local area network. Instrumentation of the Gemini/Almini optimization routines reveals significant potential for improving performance via parallelism. Using these instrumentation results, we identify promising targets of parallelism and discuss two preliminary implementations that demonstrate the potential benefits of cost-effective parallel implementations. By applying parallelism to the Almini/Gemini routines, we hope to potentially improve the performance of a large number of genetic epidemiological applications.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
ChemInform Abstract: Preparation and Crystal Structure of CsSb2PO8. (1990)

Abstract Colorless single crystals of the title compound are grown from mixtures of CsNO 3 , Sb 2 O 3 , and NH 4 H 2 PO 4 at 1173 K. The new compound belongs to the monoclinic space group C2/m with Z = 8. Its crystal structure consists of corner‐ or edge‐sharing SbO 6 octahedra and PO 4 tetrahedra linked to the octahedra via corners to form a three‐dimensional framework.
Stacking fault formation in highly doped 4H-SiC epilayers during annealing (2002)

Stacking fault formation in n+ 4H-SiC epilayers (n=9×1019 cm−3) deposited on the 4H-SiC substrates (n=5×1018 cm−3) has been observed by conventional and high-resolution transmission electron microscopy (HRTEM). Formation of faults occurred during annealing in Ar at 1150 °C for 90 min. All faults were identical double layer Shockley faults formed by the glide of partial dislocations on two neighboring basal planes. The sign of the Burgers vector for several of the partial dislocations bounding the faults at the epilayer/substrate interface has been determined by HRTEM. Approximately half the dislocations had a sign corresponding to the extra half-plane inserted into the epilayer, while the other half resulted in the removal of the same half-plane from the film. In one case, two faults bounded by opposite sign dislocations were separated by only 80 nm. This result is inconsistent with mechanical stress due to the doping difference between the epilayer and the substrate as a driving force of fault expansion.
Latency of peripheral saccades (1979)

Displaying the point of gaze to the observer in addition to a point target provides a secondary visual feedback (2VFB). Eccentric fixation is achieved using a biased 2VFB to yield an experimentally imposed "eccentric fovea." The target is suddenly moved to a new position and the task is to regain it, in the "eccentric fovea". It is found that the pattern of eye-movement response consistently starts with saccadric foveal exploration of the target, but its latency has twice the duration of a regular voluntary saccade. Practice, however, makes for the shortened latency tending asymptotically to the regular saccadic duration.
Optimization of high-speed electromagnetic systems with accurate parametric macromodels generated using sequential sampling of the design space (2012)

This paper presents a design optimization approach for electromagnetic systems using parametric macromodels. The parametric macro-models are generated using an efficient sequential sampling of the design space of interest which ensures optimal sample selection for a required level of accuracy. The proposed method is validated on a microwave notch filter example for which the parametric macromodel is used in a minimax optimization algorithm so that the design parameters are optimized for some specific electrical design performances.
Platinum Nanoparticle Inclusion into a Carbonized Polymer of Intrinsic Microporosity: Electrochemical Characteristics of a Catalyst for Electroless Hydrogen Peroxide Production (2018)

The one-step vacuum carbonization synthesis of a platinum nano-catalyst embedded in a microporous heterocarbon (Pt@cPIM) is demonstrated. A nitrogen-rich polymer of an intrinsic microporosity (PIM) precursor is impregnated with PtCl₆<sup>2-</sup> to give (after vacuum carbonization at 700 °C) a nitrogen-containing heterocarbon with embedded Pt nanoparticles of typically 1⁻4 nm diameter (with some particles up to 20 nm diameter). The Brunauer-Emmett-Teller (BET) surface area of this hybrid material is 518 m² g<sup>-1</sup> (with a cumulative pore volume of 1.1 cm³ g<sup>-1</sup>) consistent with the surface area of the corresponding platinum-free heterocarbon. In electrochemical experiments, the heterocarbon-embedded nano-platinum is observed as reactive towards hydrogen oxidation, but essentially non-reactive towards bigger molecules during methanol oxidation or during oxygen reduction. Therefore, oxygen reduction under electrochemical conditions is suggested to occur mainly via a 2-electron pathway on the outer carbon shell to give H₂O₂. Kinetic selectivity is confirmed in exploratory catalysis experiments in the presence of H₂ gas (which is oxidized on Pt) and O₂ gas (which is reduced on the heterocarbon surface) to result in the direct formation of H₂O₂.
Low Xanthophylls, Retinol, Lycopene, and Tocopherols in Grey and White Matter of Brains with Alzheimer’s Disease (2022)

Brains with AD had substantially lower concentrations of some, but not all, xanthophylls, carotenes, and tocopherols, and several-fold higher concentrations of an unidentified xanthophyll metabolite increased in AD (XMiAD).
An analysis of thermionic space nuclear reactor power system: I. Effect of disassembling radial reflector, following a reactivity initiated accident (1993)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Mohamed S. El‐Genk, Dmitry Paramonov; An analysis of thermionic space nuclear reactor power system: I. Effect of disassembling radial reflector, following a reactivity initiated accident. AIP Conf. Proc. 10 January 1993; 271 (1): 121–128. https://doi.org/10.1063/1.43230 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
VUV- and X-ray-induced Properties of Lu2Si2O7, Y2Si2O7, and Gd2Si2O7 Single Crystals (2021)

Undoped Lu 2 Si 2 O 7 (LPS), Y 2 Si 2 O 7 (YPS), and Gd 2 Si 2 O 7 (GPS) single crystals are prepared by the floating-zone (FZ) method. The X-ray diffraction (XRD) patterns show the single phase of each material without any impurity phases. The luminescence properties of the samples are investigated under both vacuum ultraviolet (VUV) and X-ray excitation. When the samples are excited by VUV photons, intrinsic emission bands at 350-500, 320-480, and 310 nm are observed for LPS, YPS, and GPS, respectively. The X-ray-induced scintillation spectra have a similar spectral shape to those under excitation by VUV photons. The X-ray induced scintillation decay times of LPS and YPS are 48 and 13 s, respectively. For GPS, two scintillation decay constants of 169 s and 1 ms are observed.
Circular forms of Uukuniemi virion RNA: an electron microscopic study (1977)

Because the ribonucleoprotein forms of the segments of the Uukuniemi virus genome have previously been characterized as circular, we examined the isolated RNAs by electron microscopy under conditions of increasing denaturation. After spreading under moderately denaturing conditions (50 or 60% formamide), 50 to 70% of the molecules were circular. Increasing the formamide concentration to 70 and 85% decreased the number of circular forms, and only linear forms were observed after incubation of the RNA at 60 degrees C for 15 min in 99% formamide. When spread from 4 M urea-80% formamide--another condition known to denature RNA--only 5 to 30% circular molecules were observed. Pretreatment of the RNA with 0.5 M glyoxal at 37 degrees C for 15 min prior to spreading from 50% formamide gave less than 5% cirucular forms. Length measurement of the molecules showed that they were not significantly degraded by any of the methods employed. The circular molecules were destroyed by treatment with pancreatic RNase, but were unaffected by DNase or proteinase K treatment. After complete denaturation of the RNA, the circles could be reformed under reannealing conditions. We conclude that the three size classes of RNA that comprise the Uukuniemi virus genome are circular molecules probably maintained in that form by base pairing between inverted complementary sequences at the 3' and 5' ends of linear molecules.
MAP estimation in particle filter tracking (2008)

Posterior densities in nonlinear tracking problems can successfully be constructed using particle filtering. The mean of the density is a popular point estimate. However, especially in multi-modal densities it does not always represent a reasonable estimate. In multi-target tracking the mean can produce a large bias when there is uncertainty about the labelling of the tracks, also referred to as the mixed labelling problem. The particle based maximum a posteriori (MAP) point estimator that has been recently developed is applied to this problem. It is shown by means of simulation that it provides a large improvement over the mean estimate.
Trinuclear Zr2,Al .mu.-ketene complexes containing bridging ligands. Implications for transmetalation reactions and carbonyl reduction chemistry (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTrinuclear Zr2,Al .mu.-ketene complexes containing bridging ligands. Implications for transmetalation reactions and carbonyl reduction chemistryRobert M. Waymouth, Bernard D. Santarsiero, Robert J. Coots, Michael J. Bronikowski, and Robert H. GrubbsCite this: J. Am. Chem. Soc. 1986, 108, 7, 1427–1441Publication Date (Print):April 1, 1986Publication History Published online1 May 2002Published inissue 1 April 1986https://pubs.acs.org/doi/10.1021/ja00267a012https://doi.org/10.1021/ja00267a012research-articleACS PublicationsRequest reuse permissionsArticle Views331Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Genetic variations in human papillomavirus and cervical cancer outcomes (2018)

Cervical cancer is driven by persistent infection of human papillomavirus (HPV), which is influenced by HPV type and intratypic variants, yet the impact of HPV type and intratypic variants on patient outcomes is far less understood. Here, we examined the association of cervical cancer stage and survival with HPV type, clade, lineage, and intratypic variants within the HPV E6 locus. Of 1,028 HPV-positive cases recruited through the CerGE study, 301 were in-situ and 727 were invasive cervical cancer (ICC), with an average post-diagnosis follow-up of 4.8 years. HPV sequencing was performed using tumor-isolated DNA to assign HPV type, HPV 16 lineage, clade, and intratypic variants within the HPV 16 E6 locus, of which nonsynonomous variants were functionally annotated by molecular modeling. HPV 18-related types were more prevalent in ICC compared to in-situ disease and associated with significantly worse recurrence-free survival (RFS) compared to HPV 16-related types. The HPV 16 Asian American lineage D3 and Asian lineage A4 associated more frequently with ICC than with in situ disease and women with an intratypic HPV 16 lineage B exhibited a trend toward worse RFS than those with A, C, or D lineages. Participants with intratypic E6 variants predicted to stabilize the E6-E6AP-p53 complex had worse RFS. Variants within the highly immunogenic HPV 16 E6 region (E14-I34) were enriched in ICC compared to in-situ lesions but were not associated with survival. Collectively, our results suggest that cervical cancer outcome is associated with HPV variants that affect virus-host interactions.
Direct Observation of Glucose Raman Fingerprint from in vivo Skin (2021)

We demonstrate the direct observation of glucose Raman peaks from in vivo skin. The signal intensities varied proportional to the reference glucose levels and tracking spectral intensity based on the linearity enabled accurate prospective prediction.
Brush-like block copolymer synthesized via RAFT polymerization for graphene oxide aqueous suspensions (2017)

We report for the first time the applications of brush-like block copolymer in the dispersant of graphene oxide aqueous suspensions.
Spacecraft applications of advanced global positioning system technology (1988)

The purpose of this study was to evaluate potential uses of Global Positioning System (GPS) in spacecraft applications in the following areas: attitude control and tracking; structural control; traffic control; and time base definition (synchronization). Each of these functions are addressed. Also addressed are the hardware related issues concerning the application of GPS technology and comparisons are provided with alternative instrumentation methods for specific functions required for an advanced low earth orbit spacecraft.