gebhart/patrepeval huggingface dataset:
PSV-20 Effects of Enterid™ in Lactating Sow Diets on Sow and Litter Performance (2022)

Abstract A total of 196 sows (parity = 2±1.1; farrowed in 5 groups) were used in this study to evaluate the effects of feeding Enterid™ feed additive (a mixture of prebiotics, probiotics, and flavoring compounds, PMI Additives) on sow and litter performance. On day 109 of gestation, sows were moved to farrowing rooms and assigned to one of two dietary treatments, including: control and control + 0.05% Enterid™. Respective diets were fed to the sows from day 109 of gestation to weaning (weaning age: 19±0.13 day). Sow body weight (BW) and backfat thickness were measured at d 109 of gestation, within 24h after-farrow, and at weaning. Sow feed consumption was recorded daily. Individual pig BW was recorded at birth and weaning. A completely randomized design was used to test the effect of diets and ANOVA was performed with mixed models using MIXED procedure in SAS (SAS 9.4, SAS Inc.). Sows fed Enterid™ numerically had greater weaning body weight (BW; 222 kg vs. 217 kg; P = 0.11) and lost less BW (-1.14 vs. -5.38 kg; P = 0.01) and backfat (+0.5 vs. -1.5 mm, P = 0.02) from farrow to weaning compared to the control. In addition, sows fed Enterid™ numerically had greater total lactation feed intake (127 vs 123 kg; P = 0.13) and ADFI (6.64 vs 6.42 kg; P = 0.17). Enterid™ numerically reduced piglet preweaning mortality by 1% (9.15 vs 10.16%). Data of this study suggests that Enterid™ can provide benefits toward improving performance of sows and reducing mortality of preweaning piglets.
Oligonucleotide recombination in Gram-negative bacteria (2009)

This report describes several key aspects of a novel form of RecA-independent homologous recombination. We found that synthetic single-stranded DNA oligonucleotides (oligos) introduced into bacteria by transformation can site-specifically recombine with bacterial chromosomes in the absence of any additional phage-encoded functions. Oligo recombination was tested in four genera of Gram-negative bacteria and in all cases evidence for recombination was apparent. The experiments presented here were designed with an eye towards learning to use oligo recombination in order to bootstrap identification and development of phage-encoded recombination systems for recombineering in a wide range of bacteria. The results show that oligo concentration and sequence have the greatest influence on recombination frequency, while oligo length was less important. Apart from the utility of oligo recombination, these findings also provide insights regarding the details of recombination mediated by phage-encoded functions. Establishing that oligos can recombine with bacterial genomes provides a link to similar observations of oligo recombination in archaea and eukaryotes suggesting the possibility that this process is evolutionary conserved.
Supplementary Data from An Epigenetic Marker Panel for Detection of Lung Cancer Using Cell-Free Serum DNA (2023)

&lt;p&gt;Supplementary Figure S1; Supplementary Tables S1-S3.&lt;/p&gt;
Trading-off stability for efficiency in designing switching-mode GaN PAs for WiMAX applications (2009)

This paper presents a 10 W, 2.4 GHz switching-mode power with a GaN HEMT transistor for WiMAX applications. By trading the stability for the efficiency, the overall power efficiency of the designed PA can be increased. It is shown in this paper that the parasitic effect introduced by the stability circuit affects the waveform shaping at large-signal drive level in switching mode PAs and consequently degrades its maximum peak efficiency. Hence, by using a potentially instable design, the efficiency and gain performance of a given transistor can be increased compared to an unconditionally stable design. To validate this approach an inverse class F PA was manufactured and tested. The power added efficiency and gain performance increased by 3.5% and 0.25 dB to reach 72% and 14.5 dB, respectively, when using a potentially instable design.
Electrodeposited, Transverse Nanowire Electroluminescent Junctions (2016)

The preparation by electrodeposition of transverse nanowire electroluminescent junctions (tn-ELJs) is described, and the electroluminescence (EL) properties of these devices are characterized. The lithographically patterned nanowire electrodeposition process is first used to prepare long (millimeters), linear, nanocrystalline CdSe nanowires on glass. The thickness of these nanowires along the emission axis is 60 nm, and the width, wCdSe, along the electrical axis is adjustable from 100 to 450 nm. Ten pairs of nickel-gold electrical contacts are then positioned along the axis of this nanowire using lithographically directed electrodeposition. The resulting linear array of nickel-CdSe-gold junctions produces EL with an external quantum efficiency, EQE, and threshold voltage, Vth, that depend sensitively on wCdSe. EQE increases with increasing electric field and also with increasing wCdSe, and Vth also increases with wCdSe and, therefore, the electrical resistance of the tn-ELJs. Vth down to 1.8(±0.2) V (for wCdSe ≈ 100 nm) and EQE of 5.5(±0.5) × 10(-5) (for wCdSe ≈ 450 nm) are obtained. tn-ELJs produce a broad EL emission envelope, spanning the wavelength range from 600 to 960 nm.
ChemInform Abstract: 1‐(2‐Pyridinyl)piperazine Derivatives with Antianaphylactic, Antibronchospastic, and Mast Cell Stabilizing Activities. (1987)

Abstract Aromatic acid chlorides (I) or amines (VII) are transformed into the amides (V) and (IX), as outlined in the reaction scheme.
Disseminated ependymomas of the central nervous system (1996)

Ependymomas are rare central nervous system (CNS) neoplasms that occasionally disseminate along the neuraxis or to extraneural sites. Definitive criteria predictive of dissemination have yet to be determined. One hundred forty patients with CNS ependymoma (88 primary spinal and 52 primary intracranial tumors) were surgically treated by the senior author (F.J.E.) between 1986 and 1994. Sixteen patients (11.4%) demonstrated tumor dissemination. The disseminated group consisted of 11 (12.5%) of 88 primary spinal and five (9.6%) of 52 primary intracranial ependymomas. The authors retrospectively reviewed the patients with CNS ependymoma and have identified several characteristics associated with dissemination from the primary tumor site. The mean time from diagnosis to dissemination was 6.8 years. The patients with disseminated disease were younger (16.8 vs. 28.3 years old, p = 0.02), had fewer gross-total resections (29% vs. 68%, p = 0.015), and had tumors with higher proliferative indices (MIB-1 staining, 13.14% vs. 2.06%, p = 0.02). High-grade tumors had a mean proliferation index of 21%, versus 2.4% and 1.6% for myxopapillary and low-grade tumors, respectively (p = 0.0003). In contrast to previous studies, tumor histology was the most significant variable for time to dissemination as determined by multivariate analysis (p = 0.008). Myxopapillary and high-grade tumors were 3.6 and 5.6 times more likely to have a shorter time to dissemination than low-grade tumors. In addition, dissemination is associated with a worse prognosis. At follow-up review, 31% of patients with disseminated disease had died compared to 7% of patients without dissemination (p = 0.04). It is concluded that younger patients with subtotal resections, myxopapillary or high-grade histology, and tumors with high proliferative indices are at substantial risk for the development of disseminated disease during their clinical course.
Polarity control during molecular beam epitaxy growth of Mg-doped GaN (2003)

Mg doping has been found in some situations to invert growth on Ga-face GaN to N-face. In this study, we clarified the role the Ga wetting layer plays in rf plasma molecular beam epitaxy of GaN when Mg doping, for [Mg] from ∼2×1019 to ∼1×1020 cm−3 corresponding to the useful, accessible range of hole concentrations of p∼1017–1018 cm−3. Structures were grown in the N-rich and Ga-rich growth regime for single Mg doping layers and for multilayer structures with a range of Mg concentrations. Samples were characterized in situ by reflection high-energy electron diffraction and ex situ by atomic force microscopy, transmission electron microscopy, convergent beam electron diffraction, and secondary ion mass spectroscopy. Growth on “dry” surfaces (without a Ga wetting layer) in the N-rich regime completely inverted to N-face upon exposure to Mg. No reinversion to Ga-face was detected for subsequent layers. Additionally, Mg was seen to serve as a surfactant during this N-rich growth, as has been reported by others. Growth initiated in the Ga-rich regime contained inversion domains that nucleated with the initiation of Mg doping. No new inversion domains were found as the Mg concentration was increased through the useful doping levels. Thus the Ga wetting layer was found to inhibit nucleation of N-face GaN, though a complete wetting layer took time to develop. Finally, by establishing a complete Ga wetting layer on the surface prior to growth, we confirmed this finding and demonstrated Mg-doped GaN completely free from inversion domains to a doping level of [Mg]∼2×1020.
Effects of Low Doses of a Novel dsRNA-based Biopesticide (Calantha) on the Colorado Potato Beetle (2023)

The Colorado potato beetle, Leptinotarsa decemlineata (Coleoptera: Chrysomelidae) is a destructive pest of the cultivated potato, Solanum tuberosum. Members of this species are well-suited to agricultural habitats because of a suite of physiological adaptations and their ability to evolve resistance to multiple insecticides. Recently, a novel double-stranded RNA (dsRNA) insecticide (Calantha, active ingredient ledprona) has been demonstrated as an effective tool to manage Colorado potato beetle populations through RNA interference (RNAi). Previous studies have demonstrated the lethality of the high doses of ledprona but had not assessed possible effects of low doses that may happen due to product degradation in the environment, incomplete spray coverage, and foliage growth. Exposure of fourth instar larvae to low concentrations of ledprona interfered with their pupation. Exposure of adults significantly reduced their mobility after seven days, as well as their fertility. Reproductive effects were stronger in females, especially when exposed before reaching sexual maturity. The observed effects of low doses of ledprona may aid in the overall management of Colorado potato beetles by reducing the size of resident populations, inhibiting beetle movement within and between fields, and reducing the population growth rate.
ChemInform Abstract: Synthesis of α‐Hydroxyphosphonates on Phosphated Supports in the Absence of Solvent. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Supramolecular Assembling Systems Formed by Heme—Heme Pocket Interactions in Hemoproteins (2013)

Abstract Review: 110 refs.
Biosynthesis of Modular Ascarosides in C. elegans (2017)

The nematode Caenorhabditis elegans uses simple building blocks from primary metabolism and a strategy of modular assembly to build a great diversity of signaling molecules, the ascarosides, which function as a chemical language in this model organism. In the ascarosides, the dideoxysugar ascarylose serves as a scaffold to which diverse moieties from lipid, amino acid, neurotransmitter, and nucleoside metabolism are attached. However, the mechanisms that underlie the highly specific assembly of ascarosides are not understood. We show that the acyl-CoA synthetase ACS-7, which localizes to lysosome-related organelles, is specifically required for the attachment of different building blocks to the 4'-position of ascr#9. We further show that mutants lacking lysosome-related organelles are defective in the production of all 4'-modified ascarosides, thus identifying the waste disposal system of the cell as a hotspot for ascaroside biosynthesis.
Alteration learning in social anxiety disorder: An fMRI study (2009)

The present study attempts to challenge the orbitofrontal cortex by using a learning paradigm which is specifically subserved by this cortical region. We implemented a version of alternation learning specifically designed for fMRI and assessed the cognitive performance and fMRI response in wide range of social anxiety disorder (SAD) severity (n=15). The main regions that were activated by the alternation learning task included portions of frontal and orbitofrontal cortex as well as the calcarine fissure. Correlations between brain activation and performance of the alternation learning task were found, among other regions, in the left and right orbitofrontal cortex. Highest correlations between degree of activation and the anxiety scores as assessed by the Leibovitch Social Anxiety Scale (LSAS) were obtained in the left temporal region as well as orbitofrontal cortex. This study supports the involvement of the orbitofrontal cortex in emotion and cognitive regulation in SAD.
XPAT® proteins, conditionally activated T-cell engagers engineered to mitigate on-target, off-tumor toxicity for immunotherapy of solid tumors (2022)

Abstract To enhance the therapeutic index of T-cell engagers (TCE), we engineered masked, conditionally active TCEs (XPAT proteins), targeting a tumor antigen (human epidermal growth factor receptor 2 [HER2] or epidermal growth factor receptor 2 [EGFR]) and CD3. Unstructured XTEN ® polypeptide masks flank the N- and C-termini of the TCE and are designed to be released by proteases in the tumor microenvironment. In vitro , unmasked HER2-XPAT (uTCE) demonstrates potent cytotoxicity, with XTEN polypeptide masking providing up to 4-log-fold protection. In vivo , HER2-XPAT induces protease-dependent anti-tumor activity and is proteolytically stable in healthy tissues. In non-human primates (NHPs), HER2-XPAT demonstrates a strong safety margin (&gt; 400-fold increase in tolerated maximum concentration versus uTCE). HER2-XPAT cleavage is low and similar in plasma samples from healthy and diseased humans and NHPs, supporting translatability of stability to human patients. The EGFR-XPAT confirmed the utility of XPAT technology for tumor targets more widely expressed in healthy tissues.
Chromatic-dispersion-insensitive PMD monitoring of 20-Gb/s DQPSK and 10-Gb/s DPSK using DGD-generated polarization-based interferometer filter (2007)

We experimentally demonstrate a chromatic dispersion insensitive PMD monitoring technique using a polarization-based interferometer filter for phase-shift-keyed transmission systems. This technique can monitor 0~100ps of DGD, insensitive to 0-650 ps/nm chromatic dispersion. (2 pages)
Geochemistry of Metal Complexes in Petroleum, Source Rocks, and Coals: An Overview (1987)

The geochemistry of metal complexes in fossil fuels and their precursors is almost entirely that of the metalloporphyrins. The evolution of the metalloporphyrins during early-late stage diagenesis and catagenesis of sediments involves primarily the progressive defunctionalization and reduction of chlorophylls -a, -b, -c1, -c2 and bacteriochlorophylls-a, -b, -d followed by metallation of the free-base porphyrins in maturing sediments. The role of the mineral matrix and sedimentary kerogens in porphyrin evolution is discussed. The geochemical processes involved in petroleum generation (migration, maturation, alteration), their effects on Ni(II) and VO(II) porphyrin evolution and implications for exploration are also discussed. The geochemistry of the Fe(III), Ga(III), and Mn(III) porphyrins in coals reflects the different, more oxic, depositional conditions of coal formation compared to those of petroleum source beds.
Sense Of Chromophore Orientation In APD Films (1999)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text W. N. HERMAN, M. J. ROBERTS, and G. A. LINDSAY, "SENSE OF CHROMOPHORE ORIENTATION IN APD FILMS," in Organic Thin Films for Photonic Applications, OSA Technical Digest (Optica Publishing Group, 1999), paper PD1. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Nanostructured Sublayers for Improved Light Extraction of Top-Emitting and Transparent Organic Electroluminescent Devices (2007)

The work focused on developing flat-panel transparent display using organic light emitting diode. Microstructure Bragg mirrors were also implemented for higher external luminous efficiency and wider color gamut. In addition, organic phosphorescent light emitting materials and devices were studied.
Perception of stereo at different vergence distances: Implications for realism (2012)

Stereoscopic 3-Dimensional (S3D) technology has recently received new considerations for two main reasons: the growing attractiveness in rendering depth for media entertainment, and the advance in 3D display technologies which now broadly dominates the use of anaglyphs. The counterpart of this interest is the list of to-be-solved problems that interfere with the spectators' quality of experience. One aspect that has received little attention is the deterioration of 3D perception with changing vergence. Two recent studies have shown that changing the vergence distance through binocular disparities affected the perception of 3D shape in such a way that objects displayed behind the screen (with uncrossed disparities) appeared flattened while objects displayed in front of the screen plane (with crossed disparities) were perceived elongated in depth [1][2]. In this study, we investigate the perception of 3D shape of random-dot stereograms at several vergence distances displayed with crossed disparities and then discuss our results according to a model of focus and vergence signals combination for scaling distance in 3D estimation. The implications of our results are discussed in the context of rendering correct S3D content.
A Modified Electromigration Test Structure for Flip Chip Interconnections (2006)

Due to decreasing dimensions, electromigration becomes a major concern for flip chip joint reliability. A novel test structure for in-situ monitoring of electromigration in a flip chip connection is proposed. With this structure, small resistance changes at the cathodic and anodic sides can be mounted separately. This allows studying the asymmetric behavior of solder joints under electromigration conditions. The design of the new test structure is described and compared to the traditional measurement method. As a first test case, a Cu-Sn-Cu flip chip joint, stressed with a current of 6000Amp/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> at 150degC, is studied. First tests clearly indicate diverging resistance values when comparing the cathodic and anodic side of the flip chip bumps. Microstructural analysis shows extensive Cu-migration from cathode to anode
The Turing Machine Model of Sensing, Manipulation, and Control (1989)

This paper presents the analysis of a robotic mail singulation system in terms of a Turing machine. The system utilizes a three dimensional vision system to identify mail parcels which are presented in a random heap for subsequent pickup by a manipulator. To complicate the problem, the mail heap moves on a rotary conveyor belt past the imaging system which is located "upstream" from the robot's work area. The Turing machine model is used to define the relationship among the actions of sensing, manipulation and control. A formalism of sense-compute-act is used in order to make the problem manageable in that the system deals only with the present state and input and produces an output which is solely a function of the present state and input. This model has been implemented in an actual functioning prototype system for the United States Postal Service. The system has been successfully tested in a real, noisy and dynamic environment.
6-DOF GraspNet: Variational Grasp Generation for Object Manipulation (2019)

Generating grasp poses is a crucial component for any robot object manipulation task. In this work, we formulate the problem of grasp generation as sampling a set of grasps using a variational autoencoder and assess and refine the sampled grasps using a grasp evaluator model. Both Grasp Sampler and Grasp Refinement networks take 3D point clouds observed by a depth camera as input. We evaluate our approach in simulation and real-world robot experiments. Our approach achieves 88% success rate on various commonly used objects with diverse appearances, scales, and weights. Our model is trained purely in simulation and works in the real-world without any extra steps.
Low Temperature CNT Growth Kinetics on Metallic Substrates for Interconnects (2013)

status: Published
Design, Synthesis, and Characterization of Well-Defined Amorphous Molecules for Use in Organic LEDs (2003)

Two strategies are presented for making amorphous organic chromophores with well-defined dimensions that exploit the superior qualities of polymers and small molecules with respect to LED fabrication. These qualities are resistance to crystallization, purity, high luminescence efficiency, and high solubility required for spin casting. Tetrakis(4-(4'-(3",5"-dihexyloxystyryl)styryl)stilbenyl)methane (T-4R-OC6H13) exemplifies a strategy consisting of four oligophenylenevinylene fragments ("arms") connected to a tetrahedral point of convergence. Bulk samples are amorphous and the film-forming qualities are useful for the fabrication of LEDs with low turn-on voltages. In a related strategy, tris[1-(N-ethylcarbazolyl)-1-(3',5'-hexyloxybenzoyl) methane]-(phenanthroline) europium was designed using a modular approach. It incorporates functionalities for electron and hole transport, solubility, and resistance to crystallization. LEDs were fabricated and studied.