gebhart/patrepeval huggingface dataset:
Novel 10-channel phased-array coil design for carotid wall MRI at 3T (2022)

Abstract Background Accurate assessment of plaque accumulation near the carotid bifurcation is important for the effective prevention and treatment of stroke. However, vessel and plaque delineation using MRI can be limited by low contrast-to-noise ratio (CNR) and long acquisition times. In this work, a novel 10-channel phased-array receive coil design for bilateral imaging of the carotid bifurcation using 3T MRI is proposed. Methods The novel 10-channel receive coil was compared to a commercial 4-channel receive coil configuration using data acquired from phantoms and healthy volunteers (N = 9). The relative performance of the coils was assessed, by comparing signal-to-noise ratio (SNR), g-factor noise amplification, and the CNR between vessel wall and lumen using black-blood sequences. Patient data were acquired from 12 atherosclerotic carotid artery disease patients. Results The 10-channel coil consistently provided substantially increased SNR in phantoms (+88 ± 2%) and improved CNR in healthy carotid arteries (+62 ± 11%), or reduced g-factor noise amplification. Patient data showed excellent delineation of atherosclerotic plaque along the length of the carotid bifurcation using the 10-channel coil. Conclusions The proposed 10-channel coil design allows for improved visualization of the carotid arteries and the carotid bifurcation and increased parallel imaging acceleration factors.
Micro Reaction Technology in Organic Synthesis. Von Charlotte Wiles und Paul Watts. (2012)

CRC Press, Boca Raton, 2011. 453 S., geb., 89.00 £.—ISBN 978-1439824719
Ultra-wide band fiber pairs with accurate slope compensation over an extended wavelength range (2002)

A novel transmission fiber has been designed for ultra-wide band applications from 1260-1625 nm. When combined with a matching compensation fiber, the dispersion tolerance across the C- and extended L-bands is less than 0.025 ps/nm/km
1.8 kV, 3.8 A bipolar junction transistors in 4H-SiC (2002)

High voltage npn bipolar junction transistors in 4H-SiC are presented in this paper. The BJTs were able to block 1800 V in common emitter mode and showed a peak current gain of 20 and an on-resistance of 10.8 m/spl Omega//spl middot/cm/sup 2/ at room temperature. Temperature-stable current gain was observed for these devices. This is due to the higher percent ionization of the deep level acceptor atoms in the base region at elevated temperatures, which offsets the effects of increased minority carrier lifetime at high temperatures. These transistors show a positive temperature coefficient in the on-resistance characteristics, which will enable easy paralleling of the devices.
Response : Hemispheric Specialization for Language Processes (1981)

Article MetricsDownloadsCitationsNo data available.0246AugSepOctNovDecJan530Total6 Months12 MonthsTotal number of downloads for the most recent 6 whole calendar months.
Modeling energy storage and structural evolution during finite viscoplastic deformation of glassy polymers (2017)

The enthalpic response of amorphous polymers depends strongly on their thermal and deformation history. Annealing just below the glass transition temperature (T_{g}) causes a large endothermic overshoot of the isobaric heat capacity at T_{g} as measured by differential scanning calorimetry, while plastic deformation (cold work) can erase this overshoot and create an exothermic undershoot. This indicates that a strong coupling exists between the polymer structure, thermal response, and mechanical deformation. In this work, we apply a recently developed thermomechanical model for glassy polymers that couples structural evolution and viscoplastic deformation to investigate the effect of annealing and plastic deformation on the accumulation of stored energy during cold work and calorimetry measurements of heat flow. The thermomechanical model introduces the effective temperature as an additional state variable in a nonequilibrium thermodynamics setting to describe the structural evolution of the material. The results show that the model accurately describes the stress and enthalpy response of quenched and annealed polymers with different plastic predeformations. The model also shows that at 30% strain in uniaxial compression, 45% of the applied work is converted into stored energy, which is consistent with experimental data from literature.
Beneficial Effects of Gonadotropin-Releasing Hormone Analogue Treatment on Positive and Negative Symptoms of Schizophrenia (2004)

schizophrenia.These should include lifestyle intervention programs that focus on diet, emphasize physical activity, and teach problem-solving skills specified for patients with schizophrenia. 10 Current evidence suggests that short-term weight loss is achievable in this population, but other strategies must be generated to target long-term weight loss 10 or the prevention of weight gain.
Synthesis and Topological Trapping of Cyclic Poly(alkylene phosphates) (2014)

The zwitterionic ring-opening polymerization of 2-isopropoxy-2-oxo-1,3,2-dioxaphospholane (iPP) with N-heterocyclic carbenes (NHC) generates poly(alkylene phosphate)s with molecular weights of Mn = 55000–202000 Da. MALDI-TOF mass spectrometry provided clear evidence for cyclic poly(alkylene phosphate)s (poly(iPP)) for lower molecular weight fractions (m/z ≤ 3000). The cyclic topology of the higher molecular weight fractions was inferred by trapping of poly(iPP) in cross-linked 2-hydroxyethyl methacrylate (HEMA) hydrogels. Cross-linked HEMA hydrogels were generated in the presence of a high molecular weight (Mn = 202000 Da) poly(iPP) generated from the zwitterionic ring-opening polymerization of iPP with the NHC 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene 2. Extraction of the resulting gel with methanol for 11 days revealed that 36% of the poly(iPP) was retained in the gel, whereas a linear poly(iPP) was completely extracted under similar conditions. The retention of the poly(iPP)s in the gels is attributed to topological trapping of the cyclic poly(iPP) in the cross-linked network.
Iron concentration linked to structural connectivity in the subthalamic nucleus: implications for deep brain stimulation (2019)

Quantitative susceptibility mapping not only accurately delineates the STN borders but is also able to provide functional information about the STN functional subdivisions. The observed iron-to-connectivity correlation patterns may aid in planning DBS surgery to avoid unwanted side effects associated with DBS.
ChemInform Abstract: Novel Cyclisations of the Chalcogeno‐Phosphoryl Unit and the Formation of Genuine Heterocycles. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
pH-degradable imidazoquinoline-ligated nanogels for lymph node-focused immune activation (2016)

Agonists of Toll-like receptors (TLRs) are potent activators of the innate immune system and hold promise as vaccine adjuvant and for anticancer immunotherapy. Unfortunately, in soluble form they readily enter systemic circulation and cause systemic inflammatory toxicity. Here we demonstrate that by covalent ligation of a small-molecule imidazoquinoline-based TLR7/8 agonist to 50-nm-sized degradable polymeric nanogels the potency of the agonist to activate TLR7/8 in in vitro cultured dendritic cells is largely retained. Importantly, imidazoquinoline-ligated nanogels focused the in vivo immune activation on the draining lymph nodes while dramatically reducing systemic inflammation. Mechanistic studies revealed a prevalent passive diffusion of the nanogels to the draining lymph node. Moreover, immunization studies in mice have shown that relative to soluble TLR7/8 agonist, imidazoquinoline-ligated nanogels induce superior antibody and T-cell responses against a tuberculosis antigen. This approach opens possibilities to enhance the therapeutic benefit of small-molecule TLR agonist for a variety of applications.
A new bias field correction method combining N3 and FCM for improved segmentation of breast density on MRI (2010)

Choosing an appropriate bias field correction method is a very important preprocessing step to allow an accurate segmentation of fibroglandular tissues based on breast MRI for quantitative measurement of breast density. The proposed algorithm combining N3+FCM and CLIC both yield satisfactory results.
THE CLINICAL EFFICACY AND SAFETY STUDY OF PCI REMEDIAL TREATMENT AFTER THE (2012)

Objectives To evaluate the efficacy and safety of PCI remedial treatment after the failure of intravenous thrombolytic therapy in the aged patients with acute myocardial infarction (AMI). Methods 59 patients with acute ST-segment elevated acute myocardial infarction (STEMI) were divided into two groups according to the age: group A (&lt;65 years) and group B (≥65 years). If the infarct-related artery (IRA) failed to effectively open after thrombolytic therapy, coronary angiography (CAG) would be carried out. If the IRA blood flow during the CAG was below TIMI 3 level, and there were still more obvious chest pain and (or) the ST-segment elevation in the ECG leads corresponding to infarction, the PCI remedial treatment on IRA was completed except for emergency PCI contraindication. The effective opening ratio of thrombolytic therapy, PCI treatment success ratio and complications were compared between two groups. Results Compared with group A, the effective opening ratio of thrombolytic therapy in group B was lower, but PCI treatment success ratio after the failure of intravenous thrombolytic therapy was no significant difference between two groups. The major complications after PCI such as intracranial haemorrhage and gastrointestinal bleeding and so on didn't increased significantly in group B. Conclusions PCI remedial treatment after the failure of intravenous thrombolytic therapy has significant clinical efficacy and safety in the aged patients with AMI.
EFFECTS OF OHMIC PRETREATMENT ON OIL UPTAKE OF POTATO SLICES DURING FRYING AND SUBSEQUENT COOLING (2007)

ABSTRACT The effect of ohmic pretreatment on the oil uptake of potato slices during frying and subsequent cooling was investigated. The treated potato slices were heated by either directly sandwiching the slices between two electrodes or by heating them in a 0.11% salt solution. The treatment was carried out using an alternating current field of 35.5 V/cm. Results of this study indicate that oil uptake during frying and subsequent cooling of potato slices was decreased by the ohmic pretreatment without involving a liquid medium (direct sandwiching). However, when the ohmic pretreatment was carried out in a liquid medium, the effect was not evident. This might be due to water absorption during the treatment, which increased initial moisture content as well as porosity of the treated samples.
Large area adaptive avalanche photodetector arrays for free-space optical communication (2008)

In free space optical communication systems, atmospheric turbulence makes it very difficult to focus transmitted laser power onto small, low capacitance photodetectors. The obvious challenge, therefore, is to take advantage of larger area photodiodes without sacrificing a great deal of bandwidth and sensitivity in the process. In this work, we report on a high sensitivity, high speed adaptive avalanche photodetector array for free-space optical communication. The receiver consists of a 2&times;2 InGaAs APD array with each 100um element in the array having its own dedicated trans-impedance amplifier and buffering stage. The corresponding voltage outputs for each element are processed through a four channel digital, fast switching and summation circuit. The resulting signal is selectable to be either that of the element in the array with the greatest signal response or the sum of multiple or all channels. Design requirements, laboratory sensitivity measurements, and field testing results are presented.
Discrete Multitone Transmission In The Presence Of Optical Noise, Chromatic Dispersion And Narrow-Band Optical Filtering (2014)

The use of bit and power loading algorithms in combination with direct-detection discrete multitone (DMT) modulation enables high data rate transmission with a low-complexity transmitter and receiver setup. We show that the available bandwidth of current high-speed digital-to-analog-converters allows the transmission of 56 Gb/s data within the 1.55micrometer window over up to 200 km standard single mode fiber (SSMF) without optical dispersion compensation. By introducing asymmetrical filtering of the DMT signal, the bandwidth requirement can be reduced to below 36 GHz, which will allow the multiplexing of 56-Gb/s channels within a 50-GHz channel grid. Moreover, tight asymmetrical filtering increases the performance compared to wide symmetrical filtering, so that the reach could be extended beyond the 200 km shown within this paper.
Tunable photon-induced spatial modulation of free electrons (2022)

Spatial modulation of electron beams is an essential tool for various applications such as nanolithography and imaging1–3 , yet its implementations4–11 are severely limited and inherently non-tunable. Conversely, light-driven electron spatial modulation12–15 could potentially allow arbitrary electron wavefront shaping16–18 via the underlying mechanism of photon-induced nearfield electron microscopy (PINEM)19–21 . Here, we present tunable photon-induced spatial modulation of electrons through their externally-controlled interaction with surface plasmon polaritons (SPPs). Using recently developed methods of shaping SPP patterns 22,23, we demonstrate a dynamic control of the electron beam with a variety of high-quality electron distributions. Intriguingly, by utilizing the intrinsic interaction nonlinearity24, we attain the first observation of 2D spatial Rabi oscillations25,26 and generate electron features below the SPP wavelength. Our work paves the way to on-demand electron wavefront shaping at ultrafast timescales, with prospects for aberration correction, nano-fabrication and material characterization.
<title>Optical modulators for analog link applications</title> (1993)

Features of integrated optical modulators that are important for their use in analog link applications are summarized. The Mach-Zehnder interferometric modulator fabricated on a lithium niobate substrate is treated in detail.
Engineering and performance evaluation of the ABR service in second generation ATM networks (2003)

The ATM ABR service implements a flow control, which enables the efficient use of network resources. It can be used for providing ATM bearer services, or for carrying other cell services such as ATM VBR/UBR and packet services such as frame relay and IP. There are many ATM switch designs, ABR service parameters, and deployment options to consider. Judicious choice of these options and parameters could have significant impact on ABR performance in various networking scenarios. This paper starts by identifying the key switch design and network engineering considerations for the ABR service. Next, it provides simulation results and comparative analysis of ABR network performance under transient and steady state conditions for various flow control loop segmentation options. Finally, it concludes with engineering guidelines for the successful deployment of ABR in second generation ATM networks.
Taselisib (GDC-0032), a Potent β-Sparing Small Molecule Inhibitor of PI3K, Radiosensitizes Head and Neck Squamous Carcinomas Containing Activating PIK3CA Alterations (2015)

GDC-0032 has increased potency in HNSCC cell lines harboringPIK3CA-activating aberrations. Further, combined GDC-0032 and radiotherapy was more efficacious than either treatment alone inPIK3CA-altered HNSCCin vitroandin vivo This strategy warrants further clinical investigation.
DRAQ5 Labeling of Nuclear DNA in Live and Fixed Cells (2004)

This unit describes the use of a novel DNA-detecting far-red-fluorescing dye, DRAQ5, a modified anthraquinone, which has a unique combination of properties exploitable by cytometry. These include a high capacity to permeate the cell membrane, a high DNA binding affinity and selectivity, a fluorescence emission spectrum beyond that of fluorescein, phycoerythrin, Texas Red, Cy3, and EGFP, and excitation characteristics separate from those of propidium iodide. In this unit, methods are presented for preparation and analysis of both live and fixed cells stained with DRAQ5. While the focus is on flow cytometric assays, typical imaging applications are also indicated because the staining protocols share the same essential features.
Mesoporous Activated Carbon from Bamboo Waste via Microwave-Assisted K2CO3 Activation: Adsorption Optimization and Mechanism for Methylene Blue Dye (2022)

Bamboo waste (BW) was activated with a K2CO3 precursor in a microwave process for the adsorption of MB dye from an aqueous solution. The prepared bamboo-waste-activated carbon (BWAC) was analyzed by instrumental techniques such as FTIR, SEM, and BET analysis. The surface of the BWAC was mesoporous with a surface area of 107.148 m2/g. The MB dye removal was optimized with the three variables of adsorbent dose, pH, and contact time using the Box–Behnken design (BBD) model. Up to 87% of MB was removed in the optimized conditions of adsorbent dose of 0.08 g/100 mL, pH of 7.62, time of 8 min, and concentration of 50 mg/L. Here, the most effective parameter for MB removal was found to be adsorbent dose with an F-value of 121.70, while time and pH showed a smaller effect. The maximum adsorption capacity of BWAC in the optimized conditions was found to be 85.6 mg/g. The adsorption of MB on BWAC’s surface was through chemisorption and a spontaneous process. The adsorption mechanism study showed that three types of interactions are responsible for the removal of MB dye from aqueous solutions by BWAC, i.e., electrostatic interactions, H-bonding, and pi–pi interactions. Hence, BWAC can be considered a highly efficient adsorbent for MB removal from wastewater.
On the Use of Vertex-Frequency Analysis for Anomaly Detection in Graph Signals (2019)

Graph signals (GS) are widespread in many areas of data analysis, such as in social, genetics, and biomolecular networks as well as in several engineering applications.Detecting localized properties of GS using spectral tools while taking into account the underlying graph topology is still an active research topic called vertex-frequency analysis (VFA).This paper provides a brief and up-to-date overview on state-of-the-art VFA tools, namely windowed graph Fourier transform and spectral graph wavelet transform.In addition, the paper shows how VFA can be applied to detect and localize anomalies in GS.In the particular example of localizing a malfunctioning weather station, the average area under ROC curve achieved by the local factor outlier technique can be improved from 72% to 87% when fed with VFA-extracted features to detect small drifts in temperature measurements, ranging from 0.5 o C to 4 o C.
Quantum Key Distribution for Reconfigurable Optical Networks (2006)

Recent advances in quantum key distribution (QKD) systems for optical networks are presented including a system that is compatible with dynamic reconfiguration of the quantum channel using optical switches.
Dynamics and two photon intersubband absorption of photovoltaic quantum structures (2014)

Multiple quantum well (InAlAs/InGaAs) based photovoltaic cells and subsystems were grown by molecular beam epitaxy on (001) InP substrates to study the dynamics of the intersubband transitions and the photocurrent behavior with ultrafast and continuous wave (cw) laser spectroscopy, respectively. The surface recombination velocity was determined with photoluminescence and time domain THz spectroscopy by varying the well thickness. Two-photon absorption was observed in a photovoltaic device as an increase in photocurrent from room temperature down to 5 K by illumination of the structures at two different wavelengths.
Single Step Fluorescent Caspase 3 Activity Assay: Quantifying the Inhibition of Cell Permeable Compounds in a Cell-Based System (2001)

Caspases are a family of cysteine aspartyl proteases that are involved in the cleavage of key structural, cell signaling, and DNA repair substrates leading to apoptotic cell death (1). As a result, the modulation of caspase response is the object of intense study in clinical research. Caspase 3 is recognized as a pivotal effector and logical target for therapeutic intervention (2). To this end, we have developed a robust, highly sensitive, and rapid homogeneous caspase 3 assay that is quantifiable in cell-based assays and with purified active caspase 3. We have used this assay to monitor the efficiency of several cell-permeable caspase 3 inhibitors in the cell-based Jurkat/Fas-induction model system (3). The evaluation of these compounds by caspase activity was supported and correlated with the CaspACE TM FITC-VAD-FMK in situ cell imaging assay.
Enantioselective Catalysis, Part 481: Highly Enantioselective Catalytic Transfer-Hydrogenation of Itaconic Acid with Formates (1989)

Enantioselective catalytic transfer-hydrogenation of itaconic acid (1) yields optically pure (S)-methylsuccinic acid (2). The hydrogen source is a mixture of formic acid and an amine in the mole ratio of 5:2. The catalyst system constists of a Rh(I), Rh(II), or Rh(III) complex and the chiral phosphane bppm 6. The optical purity exceeds that achieved with Rh(I)/bppm catalysts using gaseous hydrogen.
Thermal conductivity of a Tm3+:GdVO4crystal and the operational characteristics of a microchip laser based on it (1999)

The thermal conductivity of a Tm3+:GdVO4 crystal was measured in the temperature range 50 — 300 K. At a temperature of 300 K, the thermal conductivity along the c axis amounted to 9.7 W m-1 K-1, which is higher than the thermal conductivity of a Cr:Tm:Ho :YAG crystal. A maximum output power of 1.4 W (λ=1.915 μm) was attained in a Tm3+:GdVO4 microchip laser for a lasing threshold of 5.7 W and a differential efficiency of 9.2%. A GdVO4 array was found to have a number of advantages compared with other media for the fabrication of diode-pumped lasers.
Polymer-Surfactant Aggregates at a Hydrophobic Surface Studied Using Sum-Frequency Vibrational Spectroscopy (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPolymer-Surfactant Aggregates at a Hydrophobic Surface Studied Using Sum-Frequency Vibrational SpectroscopyDavid C. Duffy, Paul B. Davies, and Andrew M. CreethCite this: Langmuir 1995, 11, 8, 2931–2937Publication Date (Print):August 1, 1995Publication History Published online1 May 2002Published inissue 1 August 1995https://doi.org/10.1021/la00008a015RIGHTS & PERMISSIONSArticle Views222Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alertsclose Get e-Alerts