gebhart/patrepeval huggingface dataset:
Regulation of Hemostatic System Function by Biochemical and Mechanical Factors (2007)

The mammalian hemostatic system has evolved to accomplish the task of sealing defects in the cardiovascular system. Hemostasis occurs in and around a disruption in a vascular conduit through which blood normally flows, and is characterized by the localized formation of thrombus. Consequently, the process of hemostasis is influenced by: (1) the biochemical properties of the cellular and soluble components of the hemostatic system, counterregulatory networks, and the vascular conduit; (2) the local hemodynamic conditions, which regulate the influx and efflux of substrates, cofactors, and catalysts, and which also impose loads on the forming clot; and (3) the local mechanical properties of the vasculature. We review the components of the hemostatic and negative regulatory systems and their biochemical functions, and the roles that local hemodynamics play in the regulation of hemostasis
Enabling Drilling Operations Using Structured Data and Measured Response (2017)

Abstract The scope of this paper is to show how digitized, structured data, as a combination of design data, operational data, riser analyses and measured riser response can be used to enable drilling operations on a subsea exploration with well challenging soil or/and harsh environmental conditions. The structural integrity of the well foundation and soil support has been verified by combining the structured data obtained from measurements with the design information. A sensor system has been fitted to the riser and BOP on mobile drilling units to monitor soil and structural integrity. The combination of pre-operational assessments and monitoring during operations has been carried out for 7 consecutive drilling campaigns, with two different semi-submersible drilling rigs. The work presented in this paper will give a comparison between the measured response and the up-front design analysis, and show show to combine the design information with operational data and measured response to enable future operations. During the design phase of a subsea exploration well a wide range of design assumptions must be considered. The range in high and low estimates for parameters such as soil support or riser and BOP mass and damping forces may be considerable. In general conservative parameters must be selected, leading to worst case scenarios, which again may lead to limited operational windows, introduce high cost mitigating actions or in worst case prevent operations from being carried out. This paper will present the benefit of using actual measured response and operational parameters back into the design loop when planning upcoming drilling campaigns. Structured operational data and measured response is used to improve analysis models; which lead to reduced conservatism. For cases of re-entry on an existing exploration well with heavier equipment, the measured soil support can be used to rule out some worst-case scenarios, and enable the upcoming operation. A case example of an exploration campaign enabled by the design loop will be shown.
ChemInform Abstract: SYNTHESIS OF NEW CHIRAL BICYCLIC AMINOPHOSPHORANES AND OF RHODIUM(I) CHELATES DERIVED FROM THEIR OPEN‐FORM TAUTOMERS. ISOLATION AND CHARACTERIZATION OF AN OPTICALLY PURE RHODIUM(I) NITROGEN/PHOSPHORUS CHELATE (1985)

Abstract Die Umsetzung der optisch reinen aktiven Aminodiole (I) mit Bis‐[diethylamino]‐phenylphospin ergibt die optisch reinen bicyclischen Aminophosphorane (II) als l :l‐Gemische zweier Diastereoisomerer, die aufgrund des chiralen P‐Zentrums und des zusätzlich eingeführten asymm. C‐Atoms entstehen.
Design of Cost-Effective Water-Cooled Pinfin Heatsinks (2013)

This paper presents the multi-objective optimization of cost-effective pinfin heatsinks. Heat transfer rate and pressure drop were the objective functions, and four parameters (height, diameter, longitudinal pitch, and transverse pitch) were the design variables. The relationship between the objective functions and the design variables for pinfin heatsink was calculated by using our own empirical equations using the aspect ratio and the minimum gap considering cost-effectiveness and manufacturability. Non-dominated solutions to the objective functions were illustrated, and we derived the design rules for design variables. We found the similarity of the optimum trade-off curves between the heat transfer rate and the pressure drop if the multiplication of the height and the minimum gap were the same for the different constraints. We validated our calculated solutions by comparing them with experimental results and attained reasonable agreement between the calculation and experiment.
Supplementary Figure S5 from EGFR and RB1 as Dual Biomarkers in HPV-Negative Head and Neck Cancer (2023)

&lt;p&gt;(A and B) KM survival curves specimens with (A) high EGFR stratified by wild type (WT) or amplified (AMP) CCND1, or cases with (B) low EGFR stratified by p16 mRNA expression (TCGA cohort), (C) correlation between medium CDK6 (M) or high CDK6 (H) mRNA expression and CCND1 expression. m = slope. mRNA data for 243 HPV- HNSCC samples (6) were downloaded using cBioportal (26, 27). Please also see Figure 4.&lt;/p&gt;
ChemInform Abstract: Total Synthesis of Caloporoside. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Ligand dissociation in octahedral ruthenium(II) complexes containing both unidentate and bidentate phosphine ligands (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLigand dissociation in octahedral ruthenium(II) complexes containing both unidentate and bidentate phosphine ligandsLeRoy L. Whinnery, Hong Jun Yue, and John A. MarsellaCite this: Inorg. Chem. 1986, 25, 23, 4136–4139Publication Date (Print):November 1, 1986Publication History Published online1 May 2002Published inissue 1 November 1986https://pubs.acs.org/doi/10.1021/ic00243a017https://doi.org/10.1021/ic00243a017research-articleACS PublicationsRequest reuse permissionsArticle Views217Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Next-Generation Laser for Inertial Confinement Fusion (1998)

We are developing and building the ''Mercury'' laser system as the first in a series of a new generation of diode-pumped solid-state lasers (DPSSL) for advanced high energy density (HED) physics experiments at LLNL. Mercury will be the first integrated demonstration of a scalable laser architecture compatible with advanced Inertial Confinement Fusion (ICF) goals. Primary performance goals include 10% efficiencies at 10 Hz and a &lt;10 ns pulse with l {omega} energies of 100 J and with 2 {omega}/3 {omega} frequency conversion. Achieving this performance will provide a near term capability for HED experiments and prove the potential of DPSSLs for inertial fusion energy (IFE).
Impact of Al2O3 Passivation on the Photovoltaic Performance of Vertical WSe2 Schottky Junction Solar Cells (2020)

Transition metal dichalcogenide (TMD) materials have emerged as promising candidates for thin-film solar cells due to their wide bandgap range across the visible wavelengths, high absorption coefficient, and ease of integration with both arbitrary substrates and conventional semiconductor technologies. However, reported TMD-based solar cells suffer from relatively low external quantum efficiencies (EQE) and low open circuit voltage due to unoptimized design and device fabrication. This paper studies Pt/WSe<sub>2</sub> vertical Schottky junction solar cells with various WSe<sub>2</sub> thicknesses in order to find the optimum absorber thickness. Also, we show that the devices' photovoltaic performance can be improved via Al<sub>2</sub>O<sub>3</sub> passivation, which increases the EQE up to 29.5% at 410 nm wavelength incident light. The overall resulting short circuit current improves through antireflection coating, surface doping, and surface trap passivation effects. Thanks to the Al<sub>2</sub>O<sub>3</sub> coating, this work demonstrates a device with an open circuit voltage (<i>V</i><sub>OC</sub>) of 380 mV and a short circuit current density (<i>J</i><sub>SC</sub>) of 10.7 mA/cm<sup>2</sup>. Finally, the impact of Schottky barrier height inhomogeneity at the Pt/WSe<sub>2</sub> contact is investigated as a source of open circuit voltage lowering in these devices.
Comparing distributed acoustic sensing, vertical seismic profile data acquired with single- and multi-mode fiber optic cables (2018)

Distributed temperature sensing (DTS) requires the use of a multi-mode fiber, which has resulted in the installation of multi-mode fiber in many older wells. Distributed acoustic sensing (DAS) uses single-mode fiber, but it is possible to acquire DAS data with a multi-mode cable. We compare the single- and multi-mode DAS vertical seismic profile (FiberVSP™) data acquired in the same well and show the ability to obtain comparable products, but the signal-to-noise ratio (SNR) of the multi-mode data degrades. Presentation Date: Thursday, October 18, 2018 Start Time: 8:30:00 AM Location: 212A (Anaheim Convention Center) Presentation Type: Oral
Aerosol Processing of Materials (1993)

Recent advances in aerosol generation of materials are reviewed. Gas-to-particle and spray processes (spray pyrolysis) for powder generation and various routes for film generation are discussed from the experimental and theoretical perspectives. The range of materials generated by these routes has increased in recent years to include fullerenes and ceramic superconductors. Many metals and various oxide and nonoxide ceramics have also been added to the list of materials generated by gas-phase routes. Established aerosol routes such as vapor condensation have found widespread applications for generation of nanophase materials. The formation of quantum dots via aerosol approaches has also been demonstrated. The theoretical understanding of gas-to-particle conversion routes has advanced to include the finite rate of particle fusion or sintering occurring after collisions of particles. The modeling of spray pyrolysis systems has provided insight into the control of particle morphology and reactor design. In this review, these recent developments in aerosol generation of powders and Alms via gas-phase and spray routes are discussed with an emphasis on the material chemistries involved and the synthesis of nanophase materials.
Degradation and stabilization of lithium cobalt oxide in aqueous electrolytes (2016)

We report herein the exceptional cycle stability of lithium cobalt oxide (LCO) in aqueous electrolytes of high lithium salt concentrations.
Compatibilizer Effect of Grafted Glycidyl Methacrylate on EPDM/Organoclay Nanocomposites (2005)

The nanocomposite formation in ethylene/propylene/diene rubber (EPDM) mixed with montmorillonite modified with octadecylamine (MMT-ODA) was investigated. The rubber formulation used proved to be critical for the final materials’ properties. The combined action of the curatives and glycidyl methacrylate (GMA), which was grafted on the EPDM, resulted in better intercalation and enhanced mechanical behavior of the rubber nanocomposites.
Focused crawling in depression portal search: A feasibility study (2004)

Abstract Previous work on domain specific search services in the area of depressive illness has documented the significant human cost required to setup and maintain closed-crawl parameters. It also showed that domain coverage is much less than that of whole-of-web search engines. Here we report on the feasibility of techniques for achieving greater coverage at lower cost. We found that acceptably effective crawl parameters could be automatically derived from a DMOZ depression category list, with dramatic saving in effort. We also found evidence that focused crawling could be effective in this domain: relevant documents from diverse sources are extensively interlinked; many outgoing links from a constrained crawl based on DMOZ lead to additional relevant content; and we were able to achieve reasonable precision (88%) and recall (68%) using a J48-derived predictive classifier operating only on URL words, anchor text and text content adjacent to referring links. Future directions include implementing and evaluating a focused crawler. Furthermore, the quality of information in returned pages (measured in accordance with the evidence based medicine) is vital when searchers are consumers. Accordingly, automatic estimation of web site quality and its possible incorporation in a focused crawler is the subject of a separate concurrent study.
Hybrid solar lighting systems and components (2023)

A hybrid solar lighting system and components having at least one hybrid solar concentrator, at least one fiber receiver, at least one hybrid luminaire, and a light distribution system operably connected to each hybrid solar concentrator and each hybrid luminaire. A controller operates each component.
Enhanced Recovery After Surgery Pathway for Single-Level Minimally Invasive Transforaminal Lumbar Interbody Fusion Decreases Length of Stay and Opioid Consumption (2021)

Kerolus, Mena G MD; Yerneni, Ketan BA; Witiw, Christopher D MD, MS; Shelton, Alena MS; Canar, William Jeffrey PhD; Daily, Deval MS; Fontes, Ricardo B V MD, PhD; Deutsch, Harel MD; Fessler, Richard G MD, PhD; Buvanendran, Asokumar MD, John E O’Toole, MD, MS
Proteomics of Neuropathic Pain: Proteins and Signaling Pathways Affected in a Rat Model (2014)

The myriad proteins may be involved in the mechanisms underlying the development and maintenance of neuropathic pain, an extremely disabling condition that originates from pathology of the nervous system. To address the mechanisms, we here analyzed proteins and cellular networks in the dorsal spinal cord mediating pain processing in a well-established rat model of neuropathic pain induced by spinal nerve ligation (SNL). Labeling-based proteomic methods together with high-resolution mass spectrometry for proteome analysis were applied. 38 proteins including synapsin 1 and microtubule-associated protein 2 were identified as differently expressed in the SNL group. Pathway analysis suggests that maladaptive changes in the levels of these proteins may contribute to abnormal synaptic transmission and neuronal intracellular signaling underlying the onset and development of neuropathic pain.
Large-scale identification of novel transcripts in the human genome (2007)

Although the sequencing of the human genome has been completed, the number and identity of genes contained within it remains to be fully determined. We used LongSAGE to analyze 660,357 human transcripts from human brain mRNA and identified expression of 17,409 known genes and >15,000 different transcripts that were not annotated in genome databases. Analysis of a subset of these unannotated transcripts suggests that 85% were differentially expressed in various tissue types and that fewer than 20% would have been detected by ab initio gene predictions. These studies suggest that the human genome contains on the order of twice as many transcribed regions as are currently annotated and that experimental approaches will be required to fully elucidate the novel genes corresponding to these transcripts.
The Actoside Content Analysis in <i>Radix Rehmanniae</i> Using Near-Infrared Technology (2014)

In this paper, near-infrared diffuse reflectance spectroscopy was used to analysis the acteoside content of Radix Rehmanniae. The quantitative calibration models of acteoside content were established by the partial least square (PLS). The results showed that the correlation coefficient of calibration (R 2 ) was 0.98102, the root-mean-square error of calibration (RMSEC) was 0.00464, the root-mean-square error of prediction (RMSEP) was 0.00163, and the average recovery rate was 104.837%. So the recovery of prediction set was available. The results indicated that it was available to determine the content of actoside in Radix Rehmanniae by near-infrared spectroscopy.
First observations ofB¯s0→D+D−,Ds+D−andD0D¯0decays (2013)

First observations and measurements of the branching fractions of the ${\overline{B}}_{s}^{0}\ensuremath{\rightarrow}{D}^{+}{D}^{\ensuremath{-}}$, ${\overline{B}}_{s}^{0}\ensuremath{\rightarrow}{D}_{s}^{+}{D}^{\ensuremath{-}}$ and ${\overline{B}}_{s}^{0}\ensuremath{\rightarrow}{D}^{0}{\overline{D}}^{0}$ decays are presented using $1.0\text{ }\text{ }{\mathrm{fb}}^{\ensuremath{-}1}$ of data collected by the LHCb experiment. These branching fractions are normalized to those of ${\overline{B}}^{0}\ensuremath{\rightarrow}{D}^{+}{D}^{\ensuremath{-}}$, ${B}^{0}\ensuremath{\rightarrow}{D}^{\ensuremath{-}}{D}_{s}^{+}$ and ${B}^{\ensuremath{-}}\ensuremath{\rightarrow}{D}^{0}{D}_{s}^{\ensuremath{-}}$, respectively. An excess of events consistent with the decay ${\overline{B}}^{0}\ensuremath{\rightarrow}{D}^{0}{\overline{D}}^{0}$ is also seen, and its branching fraction is measured relative to that of ${B}^{\ensuremath{-}}\ensuremath{\rightarrow}{D}^{0}{D}_{s}^{\ensuremath{-}}$. Improved measurements of the branching fractions $\mathcal{B}({\overline{B}}_{s}^{0}\ensuremath{\rightarrow}{D}_{s}^{+}{D}_{s}^{\ensuremath{-}})$ and $\mathcal{B}({B}^{\ensuremath{-}}\ensuremath{\rightarrow}{D}^{0}{D}_{s}^{\ensuremath{-}})$ are reported, each relative to $\mathcal{B}({B}^{0}\ensuremath{\rightarrow}{D}^{\ensuremath{-}}{D}_{s}^{+})$. The ratios of branching fractions are $\frac{\mathcal{B}({\overline{B}}_{s}^{0}\ensuremath{\rightarrow}{D}^{+}{D}^{\ensuremath{-}})}{\mathcal{B}({\overline{B}}^{0}\ensuremath{\rightarrow}{D}^{+}{D}^{\ensuremath{-}})}=1.08\ifmmode\pm\else\textpm\fi{}0.20\ifmmode\pm\else\textpm\fi{}0.10$, $\frac{\mathcal{B}({\overline{B}}_{s}^{0}\ensuremath{\rightarrow}{D}_{s}^{+}{D}^{\ensuremath{-}})}{\mathcal{B}({B}^{0}\ensuremath{\rightarrow}{D}^{\ensuremath{-}}{D}_{s}^{+})}=0.050\ifmmode\pm\else\textpm\fi{}0.008\ifmmode\pm\else\textpm\fi{}0.004$, $\frac{\mathcal{B}({\overline{B}}_{s}^{0}\ensuremath{\rightarrow}{D}^{0}{\overline{D}}^{0})}{\mathcal{B}({B}^{\ensuremath{-}}\ensuremath{\rightarrow}{D}^{0}{D}_{s}^{\ensuremath{-}})}=0.019\ifmmode\pm\else\textpm\fi{}0.003\ifmmode\pm\else\textpm\fi{}0.003$, $\frac{\mathcal{B}({\overline{B}}^{0}\ensuremath{\rightarrow}{D}^{0}{\overline{D}}^{0})}{\mathcal{B}({B}^{\ensuremath{-}}\ensuremath{\rightarrow}{D}^{0}{D}_{s}^{\ensuremath{-}})}&lt;0.0024$ at 90% CL, $\frac{\mathcal{B}({\overline{B}}_{s}^{0}\ensuremath{\rightarrow}{D}_{s}^{+}{D}_{s}^{\ensuremath{-}})}{\mathcal{B}({B}^{0}\ensuremath{\rightarrow}{D}^{\ensuremath{-}}{D}_{s}^{+})}=0.56\ifmmode\pm\else\textpm\fi{}0.03\ifmmode\pm\else\textpm\fi{}0.04$, $\frac{\mathcal{B}({B}^{\ensuremath{-}}\ensuremath{\rightarrow}{D}^{0}{D}_{s}^{\ensuremath{-}})}{\mathcal{B}({B}^{0}\ensuremath{\rightarrow}{D}^{\ensuremath{-}}{D}_{s}^{+})}=1.22\ifmmode\pm\else\textpm\fi{}0.02\ifmmode\pm\else\textpm\fi{}0.07$, where the uncertainties are statistical and systematic, respectively.
Cover Picture: Catalytic Production of Conjugated Fatty Acids and Oils / Design of Ru–Zeolites for Hydrogen‐Free Production of Conjugated Linoleic Acids (ChemSusChem 6/2011) (2011)

The cover picture illustrates the conjugation of oils rich in linoleic acid, such as safflower oil. Conjugated linoleic acid (CLA) and conjugated oils are excellent drying agents in products such as paints, varnishes, and inks because of their highly reactive double bonds, while they recently have also gained attention as building blocks of bioplastics. An extensive Review on the production of CLAs according to various bio-, chemo-, and photocatalytic routes is presented by Bert Sels and co-workers on p. 684. In comparison to the state-of-the-art, the same group reports the development of a very active and selective heterogeneous catalytic system, which can be used in a hydrogen-free environment, in a Full Paper by Philippaerts et al. on p. 757. The solid catalyst contains Cs cations and ultrasmall Ru clusters in the open pore structure of a highly siliceous USY zeolite.
Molecular mechanisms of constitutive activity: mutations at position 111 of the angiotensin AT1receptor (2005)

A possible molecular mechanism for the constitutive activity of mutants of the angiotensin type 1 receptor (AT1) at position 111 was suggested by molecular modeling. This involves a cascade of conformational changes in spatial positions of side chains along transmembrane helix (TM3) from L112 to Y113 to F117, which in turn, results in conformational changes in TM4 (residues I152 and M155) leading to the movement of TM4 as a whole. The mechanism is consistent with the available data of site-directed mutagenesis, as well as with correct predictions of constitutive activity of mutants L112F and L112C. It was also predicted that the double mutant N111G/L112A might possess basal constitutive activity comparable with that of the N111G mutant, whereas the double mutants N111G/Y113A, N111G/F117A, and N111G/I152A would have lower levels of basal activity. Experimental studies of the above double mutants showed significant constitutive activity of N111G/L112A and N111G/F117A. The basal activity of N111G/I152A was higher than expected, and that of N111G/Y113A was not determined due to poor expression of the mutant. The proposed mechanism of constitutive activity of the AT(1) receptor reveals a novel nonsimplistic view on the general problem of constitutive activity, and clearly demonstrates the inherent complexity of the process of G protein-coupled receptor (GPCR) activation.
Moderator and Short Introduction to the Walther Memorial Plenary (2007)

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An application view of COORDINATORS coordination managers for first responders (2004)

This study sought to find more exon mutation sites and lncRNA candidates associated with type 2 diabetes mellitus (T2DM) patients with obesity (O-T2DM). We used O-T2DM patients and healthy individuals to detect mutations in their peripheral blood by whole-exon sequencing. And changes in lncRNA expression caused by mutation sites were studied at the RNA level. Then, we performed GO analysis and KEGG pathway analysis. We found a total of 277 377 mutation sites between O-T2DM and healthy individuals. Then, we performed a DNA-RNA joint analysis. Based on the screening of harmful sites, 30 mutant genes shared in O-T2DM patients were screened. At the RNA level, mutations of 106 differentially expressed genes were displayed. Finally, a consensus mutation site and differential expression consensus gene screening were performed. In the current study, the results revealed significant differences in exon sites in peripheral blood between O-T2DM and healthy individuals, which may play an important role in the pathogenesis of O-T2DM by affecting the expression of the corresponding lncRNA. This study provides clues to the molecular mechanisms of metabolic disorders in O-T2DM patients at the DNA and RNA levels, as well as biomarkers of the risk of these disorders.