gebhart/patrepeval huggingface dataset:
Accuracy of a battery-powered portable capnometer in neonates (2020)

Abstract End-tidal CO 2 measurement (EtCO 2 ) is useful for confirmation of successful tracheal intubation and ensuring adequate ventilation. There are two types of EtCO 2 detector, i.e., single-use-only devices and capnometers. Although portable capnometers are widely used for resuscitation, there have been no reports regarding their clinical utility in neonates. Here, the correspondence between EtCO 2 level determined using a battery-powered portable capnometer and arterial CO 2 (PaCO 2 ) was investigated using paired data obtained simultaneously from 26 neonates weighing 1262 ± 589 g at examination on mechanical ventilation. EtCO 2 level and PaCO 2 showed a strong correlation (r = 0.839, P &lt; 0.001), and the correlation equation was: EtCO 2 = 0.8 × PaCO 2 + 1.1. Therefore, EtCO 2 readings obtained with a battery-powered portable capnometer were likely to be underestimated. This became more pronounced with decreasing infant body weight at examination as the net difference in measurements of PaCO 2 and EtCO 2 was significantly positively correlated with infant body weight at examination (r = 0.451, P &lt; 0.001). The observations presented here may be helpful in the use of battery-powered portable capnometers in neonates requiring controlled ventilation with tracheal intubation.
Visual detection of Brucella in bovine biological samples using DNA-activated gold nanoparticles (2017)

Brucellosis is a bacterial disease, which, although affecting cattle primarily, has been associated with human infections, making its detection an important challenge. The existing gold standard diagnosis relies on the culture of bacteria which is a lengthy and costly process, taking up to 45 days. New technologies based on molecular diagnosis have been proposed, either through dip-stick, immunological assays, which have limited specificity, or using nucleic acid tests, which enable to identify the pathogen, but are impractical for use in the field, where most of the reservoir cases are located. Here we demonstrate a new test based on hybridization assays with metal nanoparticles, which, upon detection of a specific pathogen-derived DNA sequence, yield a visual colour change. We characterise the components used in the assay with a range of analytical techniques and show sensitivities down to 1000 cfu/ml for the detection of Brucella. Finally, we demonstrate that the assay works in a range of bovine samples including semen, milk and urine, opening up the potential for its use in the field, in low-resource settings.
DSP Aided High Symbol Rate Signal Generation (2017)

We review digital-signal-processing (DSP) aided technologies for high symbol rate signal generation. Details on DSP for a 240 GSa/s and 100-GHz digital-band-interleaved (DBI) digital-to-analog converter (DAC) are discussed.
Central arteriovenous anastomosis to treat resistant hypertension (2017)

Preliminary data using the ROX coupler to form a central arteriovenous anastomosis are very encouraging. Concerns regarding the lack of sham control are to some extent mitigated by immediate on table blood pressure reduction with opening of the coupler and will be further addressed in the ongoing pivotal, sham-controlled ROX CONTROL Hypertension2 study which should provide further robust information regarding efficacy and safety.
Supplementary Methods and Materials from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis (2023)

Supplementary Methods and Materials from Selective Inhibition of Matrix Metalloproteinase-14 Blocks Tumor Growth, Invasion, and Angiogenesis
Role of the Helicobacter pylori virulence factors vacuolating cytotoxin, CagA, and urease in a mouse model of disease (1995)

The pathogenic role of Helicobacter pylori virulence factors has been studied with a mouse model of gastric disease. BALB/c mice were treated orally with different amounts of sonic extracts of cytotoxic H. pylori strains (NCTC 11637, 60190, 84-183, and 87A300 [CagA+/Tox+]). The pathological effects on histological sections of gastric mucosae were assessed and were compared with the effects of treatments with extracts from noncytotoxic strains (G21 and G50 [CagA-/Tox-]) and from strains that express either CagA alone (D931 [CagA+/Tox-]) or the cytotoxin alone (G104 [CagA-/Tox+]). The treatment with extracts from cytotoxic strains induced various epithelial lesions (vacuolation, erosions, and ulcerations), recruitment of inflammatory cells in the lamina propria, and a marked reduction of the mucin layer. Extracts of noncytotoxic strains induced mucin depletion but no other significant pathology. Crude extracts of strain D931, expressing CagA alone, caused only mild infiltration of inflammatory cells, whereas extracts of strain G104, expressing cytotoxin alone, induced extensive epithelial damage but little inflammatory reaction. Loss of the mucin layer was not associated with a cytotoxic phenotype, since this loss was observed in mice treated with crude extracts of all strains. The pathogenic roles of CagA, cytotoxin, and urease were further assessed by using extracts of mutant strains of H. pylori defective in the expression of each of these virulence factors. The results obtained suggest that (i) urease activity does not play a significant role in inducing the observed gastric damage, (ii) cytotoxin has an important role in the induction of gastric epithelial cell lesions but not in eliciting inflammation, and (iii) other components present in strains which carry the cagA gene, but distinct from CagA itself, are involved in eliciting the inflammatory response.
Combinatorial Templates Generated by Dip-Pen Nanolithography for the Formation of Two-Dimensional Particle Arrays (2001)

Einzelne Partikel in zweidimensionalen Anordnungen präzise zu positionieren, das ist mit der DPN-Methode möglich, bei der mithilfe einer Kraftmikroskop-Spitze Moleküle von einem Wassermeniskus auf eine Oberfläche übertragen werden (DPN=dip-pen nanolithography). DPN wurde eingesetzt zur Erzeugung von 16-Thiohexadecansäure-Templaten auf einer Goldoberfläche, um die zweidimensionale Anordnung von amin- und amidinmodifizierten Partikeln zu untersuchen (siehe Bild).
ChemInform Abstract: A Two‐Component Catalyst System for Asymmetric Allylic Alkylations with Alcohol Pronucleophiles. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A Bioinspired Scaffold with Anti-Inflammatory Magnesium Hydroxide and Decellularized Extracellular Matrix for Renal Tissue Regeneration (2019)

Kidney diseases are a worldwide public health issue. Renal tissue regeneration using functional scaffolds with biomaterials has attracted a great deal of attention due to limited donor organ availability. Here, we developed a bioinspired scaffold that can efficiently induce renal tissue regeneration. The bioinspired scaffold was designed with poly(lactide-co-glycolide) (PLGA), magnesium hydroxide (Mg(OH)2), and decellularized renal extracellular matrix (ECM). The Mg(OH)2 inhibited materials-induced inflammatory reactions by neutralizing the acidic microenvironment formed by degradation products of PLGA, and the acellular ECM helped restore the biological function of kidney tissues. When the PLGA/ECM/Mg(OH)2 scaffold was implanted in a partially nephrectomized mouse model, it led to the regeneration of renal glomerular tissue with a low inflammatory response. Finally, the PLGA/ECM/Mg(OH)2 scaffold was able to restore renal function more effectively than the control groups. These results suggest that the bioinspired scaffold can be used as an advanced scaffold platform for renal disease treatment.
Data Integration is Key to Solving the Shale Gas Reservoir (2010)

Summary Shale gas development has been expanding at a rapid pace in many basins around North America and has garnered considerable interest in mature markets around the world. Success in the shale gas plays require seamless integration, analysis, and visualization of many types of data to reduce completion risk and maximize reservoir return thus leading to a more profitable project. Linking field development with operations provides a powerful approach to improving reserve management - using a model-centric approach that includes a standardized methodology and knowledge capture to improve decision making and risk management - to exploit shale gas reservoirs using fractured horizontal wells. Further, direct integration with real-time data to monitor and adapt and fracturing process while completing is critical to successful production of these reserves.
Impact of Electrolyte Viscosity on Redox Flow Battery Performance (2017)

Due to their inherent scalability and long operational lifetimes, redox flow batteries (RFBs) have shown promise as grid-level energy storage systems that enable the integration of intermittent renewable energy sources and the improvement of non-renewable energy processes on the grid. 1 However, additional cost reductions are required to reach proposed capital cost targets for widespread commercial implementation. 2 While multiple efforts have focused on discovery and development of next-generation materials for RFBs, fewer studies have systematically investigated the impact of the physical properties of electrolytes on cell performance. This is particularly relevant as many new electrolyte formulations push towards higher concentrations and incorporate new redox structures (e.g., macromolecules), which improve capacity and reduce cost, but also result in higher viscosities and greater property variation as a function of state-of-charge. These factors are expected to strongly influence cell performance. Specifically, engineering an efficient, cost-effective reactor depends on mitigation of resistive losses, several of which depend on electrolyte viscosity, and this dependence has yet to be fully characterized within a RFB. Here, we use a single-electrolyte flow cell configuration 3 , coupled with a model iron-based electrolyte, to probe the impact of electrolyte viscosity on RFB losses. Through the use of glucose as a chemically and electrochemically inert solution thickener, we investigate polarization as a function of electrolyte viscosity, electrolyte flowrate, and flow field geometry. Experimental data is combined with an one dimensional porous electrode polarization model to extract ohmic, kinetic, and mass transfer contributions to cell resistance. Of particular interest are mass transfer rates in RFBs, which are rarely quantified, thus the observed trends in mass transfer coefficient are correlated in terms of dimensionless numbers (e.g., Reynolds, Schmidt) in a traditional power-law format. This study aims to link electrolyte properties and cell performance and to provide a scalable descriptions of mass transfer in RFBs. Acknowledgments The authors acknowledge the financial support of the Joint Center for Energy Storage Research, which was formed under the Office of Basic Energy Sciences within the Department of Energy. We thank A. Helal and G. H. McKinley for rheological guidance and aid in viscosity measurements. We also thank M. Z. Bazant for use of milling equipment to fabricate flow fields used in this work. References 1. Weber, A. Z. et al. Redox flow batteries : a review. J. Appl. Electrochem. 41, 1137–1164 (2011). 2. Dmello, R., Milshtein, J. D., Brushett, F. R. &amp; Smith, K. C. Cost-driven materials selection criteria for redox flow battery electrolytes. J. Power Sources 330, 261–272 (2016). 3. Darling, R. M. &amp; Perry, M. L. The Influence of Electrode and Channel Configurations on Flow Battery Performance. J. Electrochem. Soc. 161, A1381–A1387 (2014). Figure 1
Analysis of corneal and conjunctival microenvironments using monoclonal antibodies. (1993)

The availability of tissue-specific markers of epithelial and nonepithelial components of the cornea and conjunctiva should be of use in the study of the roles the ocular microenvironment might play in the pathogenesis of ocular inflammatory diseases.
A Unique Hydraulic Fracturing Technique Using Dynamic Rock Behavior and Temporary Changes in Geomechanic Stress Anisotropy to Optimize Hydrocarbon Recovery in Unconventional Formations (2015)

Abstract In an effort to improve hydrocarbon recovery in unconventional formations, a new stimulation method was developed to take advantage of microtectonic forces created during the hydraulic fracturing process which modify the local stress anisotropy near the wellbore for a short period of time. Because of the temporary changes in the rock stress landscape from creating and extending an initial hydraulic fracture, a brief time window exists following that fracture creation wherein a secondary hydraulic fracture can be created in a similar location in a completely different direction. The second fracture provides direct connectivity to previously unattainable locations in the formation. As a result of the increased formation connectivity, a significant increase in well production is achievable. This new stimulation method greatly enhances the state-of-the-art in hydraulic fracturing, and challenges the industry to develop improved understanding of not only the static behavior of formation rocks, but also their transient behavior. This paper presents operational recommendations for conducting a multioriented hydraulic fracture (MOHF) treatment using abrasive hydra-jet assisted pinpoint hydraulic fracturing, a financial evaluation of the potential benefits of the MOHF process, and the results from a novel transient three dimensional (3D) geomechanics computational simulation of the creation of dual fractures in a formation. Details of the model are provided in addition to recommendations for improving the accuracy of the model for future application.
Development of a new imaging device using a VUV scintillator and a gas photomultiplier with a μ-PIC and GEM (2012)

We have developed a new imaging device consisting of a VUV scintillator coupled to a gas photomultiplier (gas PMT) with a CsI photocathode, micro pixel chamber (μ-PIC) and gas electron multipliers (GEMs). Nd:LuLiF4 and Nd:LuF3 scintillators were employed.
A Program Backlog Story with Patterns (2018)

This paper extends our Magic Backlog Patterns collection with three additional patterns for managing the work of a program- or rather how to deal with coordinating the work of projects which are part of a larger program and where there may be dependencies and shared deployment. While teams within a program may work fairly independently, their work still needs to be coordinated to produce a product. These three patterns, which represent alternative strategies for structuring the backlog of work, are introduced through a story of the correspondence of a business analyst as her hypothetical program moves through different backlog management strategies.
HD-PLC broadband power line communications for IoT (2020)

REE N°1/2020 Z 81 Introduction «HD-PLC,» a technology for high-speed power line communication, was standar- dized in 2010 as IEEE 1901. However, with the widespread of IoT networks, a growing range of applications is being used, creating situations where the IEEE 1901 version on HD-PLC needs to be upgraded to offer longer communica- tion distances and faster communication speeds. Many users are now demanding these types of improvements. Let’s discuss communication distance is- sues first. HD-PLC was originally designed as a communication infrastructure tech- nology to improve domestic lifestyles. It provides networks in which housing equipment, household appliances, sen- sors, etc., are permanently connected to the Internet. For building energy mana- gement systems (BEMS), factory energy management systems (FEMS), smart meters, etc., the distances between diffe- rent terminals are mostly longer than for domestic use. HD-PLC-based networks must, therefore, be robust enough to al- low terminals to communicate with each other in all given indoor communication environments. To solve the above distance-related challenge, multi-hop technology, such as ITU-T G9905, originally publish
Photoinduced anisotropy of second-harmonic generation from azobenzene-modified alkylsiloxane monolayers (2003)

Noncontact alignment of liquid crystal displays offers the advantage of reduced contamination and minimal surface charging. This approach also provides a means of reversible alignment after a device has been assembled. With this objective we have synthesized self-assembled monolayers based on dimethylaminoazobenzene units covalently attached to a glass surface by means of a short alkylsiloxane anchor, a derivatized version of methyl red (d-MR). The resulting architecture favors an orientation in which the axis of the azobenzene group should be nearly parallel to the surface with an isotropic azimuthal distribution. Under illumination with polarized light the trans–cis isomerization and subsequent relaxation serves to wiggle the molecule into an orientation perpendicular to the treatment polarization. We have tested this scenario using optical second harmonic generation and supporting optical techniques. We are able to identify a surface order parameter that characterizes the photoalignment of the azobenzene group, and have shown that the treatment illumination promotes the formation of H aggregates of the azobenzene species. We have also demonstrated that the treated d-MR layer successfully aligns a nematic liquid crystal.
Charge-Transport in Radical Polymer Membranes Leading to Organic-Based New Devices (2012)

Redox polymers, aliphatic polymers bearing organic redox-active groups per repeating unit, are characterized by an ultimate population of the electron-releasing and -gaining site, which allows efficient redox-driven electron transport throughout the polymer membrane via self-exchange reactions. The high electron-transport reactivity of redox polymers provides very fast charge-propagation and reversible charge-storage in a rechargeable battery and photovoltaic cell. Redox polymers are emerging as a new class of electroactive organic materials useful for various kinds of wet-type energy storage and conversion devices.
Comparison of the response of saline tonometry and an automated gas tonometry device to a change in CO2 (2000)

The automated gas tonometry system has a significantly faster response to a change in CO2 than conventional saline tonometry.
The identification of T2; the phosphate/pyrophosphate transport protein of the hepatic microsomal glucose‐6‐phosphatase system (1988)

The phosphate/pyrophosphate translocase protein (T2) of the hepatic microsomal glucose-6-phosphatase system was identified and then purified using antibodies raised against the rat mitochondrial phosphate/hydroxyl ion antiport protein. The T2 protein was shown to be absent in the microsomes isolated from a patient previously diagnosed as having type lc glycogen storage disease.
MassiveMIMOCommunications (2016)

Over the last two decades, multiple-input, multiple-output (MIMO) technology has been successfully deployed on a wide scale in cellular communication systems. MIMO technology involves the use of multiple antennas at one or both ends of a communication link to boost the performance and reliability through strategies such as beamforming, diversity transmission, spatial multiplexing, and interference suppression. The currently-deployed 4G/LTE cellular standards (LTE Rel-8/9/10) support a comprehensive suite of MIMO techniques for up to eight antenna ports in a single sector on the downlink and up to four transmit antennas at a mobile station. For 5G cellular communications, massive MIMO, sometimes called full dimension MIMO, is a promising technology for enhancing system performance for frequency bands ranging from under 6 GHz to 100 GHz. Also, for 5G systems deployed in higher frequency bands such as cmWaves (6–30 GHz) and mmWaves (30–100GHz), large-scale antenna arrays will be a prerequisite for overcoming the poor propagation characteristics in those bands. This chapter will describe the basics of massive MIMO and how it will satisfy the high-data-rate demands of 5G cellular systems for frequency bands up to 100 GHz. The current state of the art of MIMO technology are reviewed, and the application of large-scale antenna arrays to 5G are described. The chapter also surveys current trends in massive MIMO technology and system concepts, with a focus on methodologies for significantly enhancing cellular system performance. Various trends and promising concepts are identified, and various practical issues highlighted.
Autoantibody Cancer Biomarker: Extracellular Protein Kinase A (2006)

Abstract In cancer cells, cyclic AMP–dependent protein kinase (PKA) is secreted into the conditioned medium. This PKA, designated as extracellular protein kinase A (ECPKA), is markedly up-regulated in the sera of patients with cancer. The currently available tumor markers are based on the antigen determination method and lack specificity and sensitivity. Here, we present an ECPKA autoantibody detection method for a universal biomarker that detects cancer of various cell types. We tested sera from 295 patients with cancers of various cell types, 155 normal controls, and 55 patients without cancer. The specificity and sensitivity of this autoantibody enzyme immunoassay method were compared with the conventional antigen determination method by receiver-operating characteristic plots. In the sera, the presence of autoantibody directed against ECPKA was highly correlated with cancer. High anti-ECPKA autoantibody titers (frequency, 90%; mean titer, 3.0) were found in the sera of patients with various cancers, whereas low or negative titers (frequency, 12%; mean titer, 1.0) were found in the control group. The receiver-operating characteristic plot showed that autoantibody enzyme immunoassay exhibited 90% sensitivity and 88% specificity, whereas the enzymatic assay exhibited 83% sensitivity and 80% specificity. These results show that the autoantibody method distinguished between patients with cancer and controls better than the antigen method could. Our results show that autoantibody ECPKA is a universal serum biomarker for cancers of various cell types. (Cancer Res 2006; 66(18): 8971-4)