gebhart/patrepeval huggingface dataset:
Bis(tert-butylcyclopentadienyl)magnesium, -calcium, -strontium, and -barium metallocenes (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBis(tert-butylcyclopentadienyl)magnesium, -calcium, -strontium, and -barium metallocenesMichael G. Gardiner, Colin L. Raston, and Colin H. L. KennardCite this: Organometallics 1991, 10, 10, 3680–3686Publication Date (Print):October 1, 1991Publication History Published online1 May 2002Published inissue 1 October 1991https://pubs.acs.org/doi/10.1021/om00056a045https://doi.org/10.1021/om00056a045research-articleACS PublicationsRequest reuse permissionsArticle Views212Altmetric-Citations29LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Cálculos renales: tipos y prevención (2018)

Este libro va dirigido principalmente a los especialistas de urologia ya que, debido a la elevada prevalencia de la litiasis renal, recibe un numero considerable de pacientes con esta patologia. Pretende ser una guia sencilla de orientacion para el manejo de estos pacientes, facilitando asi la labor del urologo. El libro tambien puede ser util para el paciente interesado en conocer mejor su patologia, aunque, en ningun caso pretende sustituir al medico. Creemos que con este texto se puede proporcionar al paciente un dialogo mas fluido con su medico. El objetivo de esta obra es ofrecer un conocimiento mas completo de la enfermedad a todas las personas interesadas o preocupadas por la litiasis renal. Todo ello redundara en una asistencia al paciente mejor y mas eficaz.
Genetic evidence points to an osteocalcin-independent influence of osteoblasts on energy metabolism (2011)

The skeleton has been shown recently to regulate glucose metabolism through an osteoblast-specific hormone, osteocalcin, which favors β-cell proliferation, insulin secretion, insulin sensitivity, and energy expenditure. An implication of this finding is that a decrease in osteoblast numbers would compromise glucose metabolism in an osteocalcin-dependent manner. To test this hypothesis, osteoblasts were inducibly ablated by cross-breeding transgenic mice expressing a tamoxifen-regulated Cre under the control of the osteocalcin promoter with mice in which an inactive form of the diphtheria toxin A chain was introduced into a ubiquitously expressed locus. Ablation of osteoblasts in adult mice profoundly affected glucose metabolism. In a manner similar to what is seen in the case of osteocalcin deficiency, a partial ablation of this cell population resulted in hypoinsulinemia, hyperglycemia, glucose intolerance, and decreased insulin sensitivity. However, and unlike what is seen in osteocalcin-deficient mice, osteoblast ablation also decreased gonadal fat and increased energy expenditure and the expression of resistin, an adipokine proposed to mediate insulin resistance. While administration of osteocalcin reversed (fully) the glucose intolerance and reinstated normal blood glucose and insulin levels, it only partially restored insulin sensitivity and did not affect the improved gonadal fat weight and energy expenditure in osteoblast-depleted mice. These observations not only strengthen the notion that osteoblasts are necessary for glucose homeostasis and energy expenditure but also suggest that in addition to osteocalcin, other osteoblast-derived hormones may contribute to the emerging function of the skeleton as a regulator of energy metabolism.
Characterization of a large Lebanese family segregating IgA nephropathy (2006)

We describe one of the largest multigenerational IgAN kindreds reported to date. The high incidence of renal failure among older generations suggests a significant risk of progression to renal failure. We found no evidence of linkage to known loci, suggesting that familial IgAN encompasses multiple subtypes that will require distinction based on genetic or biomarker data.
Mask R-CNN With Pyramid Attention Network for Scene Text Detection (2019)

In this paper, we present a new Mask R-CNN based text detection approach which can robustly detect multi-oriented and curved text from natural scene images in a unified manner. To enhance the feature representation ability of Mask R-CNN for text detection tasks, we propose to use the Pyramid Attention Network (PAN) as a new backbone network of Mask R-CNN. Experiments demonstrate that PAN can suppress false alarms caused by text-like backgrounds more effectively. Our proposed approach has achieved superior performance on both multi-oriented (ICDAR-2015, ICDAR-2017 MLT) and curved (SCUT-CTW1500) text detection benchmark tasks by only using single-scale and single-model testing.
Outage Probability Analysis of IRS-Assisted Systems Under Spatially Correlated Channels (2021)

This letter investigates the impact of spatial channel correlation on the outage probability of intelligent reflecting surface (IRS)-assisted single-input single-output (SISO) communication systems. In particular, we derive a novel closed-form expression of the outage probability for arbitrary phase shifts and correlation matrices of the indirect channels. To shed light on the impact of the spatial correlation, we further attain the closed-form expressions for two common scenarios met in the literature when the large-scale fading coefficients are expressed by the loss over a propagation distance. Numerical results validate the tightness and effectiveness of the closed-form expressions. Furthermore, the spatial correlation offers significant decreases in the outage probability as the direct channel is blocked.
Purification and characterization of rat brain prostaglandin D synthetase. (1985)

Prostaglandin D synthetase was purified 2,600-fold from rat brain to apparent homogeneity, as judged by polyacrylamide gel electrophoresis and ultracentrifugation. The purified enzyme was a monomeric protein with a molecular weight of 27,000 +/- 1,000. The pI value, sedimentation coefficient, and partial specific volume were 4.6, 4.1 s, and 0.73 ml/g, respectively. The enzyme was stable between pH 4 and 11 at the temperature lower than 25 degrees C and resistant to a heat treatment under alkaline conditions (pH 8-11). About 50% of the activity was detected after a heat treatment at 100 degrees C for 5 min at pH 10. However, the enzyme was readily inactivated by the isomerase reaction of prostaglandin H2 to prostaglandin D2. The enzyme required sulfhydryl compounds such as dithiothreitol, glutathione, beta-mercaptoethanol, cysteine, and cysteamine for the reaction, but stoichiometric oxidation of these sulfhydryl compounds was not observed. The optimum pH, Km value for prostaglandin H2, and the turnover number were 9.5, 14 microM, and 170 min-1, respectively. The antibody was raised against the purified enzyme in a rabbit, which showed only one positive band in immunoblotting after gel electrophoresis of crude extracts of the brain at the same position as that of the purified enzyme. More than 90% of the prostaglandin D synthetase activity in the brain was absorbed by an excess amount of the antibody, indicating that our preparation is a major component of the enzyme responsible for the biosynthesis of prostaglandin D2 in the brain.
A Model for Hydride Transfer in Thymidylate Synthase Based on Unnatural Amino Acid Mutagenesis (1999)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTA Model for Hydride Transfer in Thymidylate Synthase Based on Unnatural Amino Acid MutagenesisJ. E. Barrett, C. M. Lucero, and P. G. SchultzView Author Information Department of Chemistry The Scripps Research Institute 10550 North Torrey Pines Road La Jolla, California 92037 Cite this: J. Am. Chem. Soc. 1999, 121, 34, 7965–7966Publication Date (Web):August 13, 1999Publication History Received1 April 1999Published online13 August 1999Published inissue 1 September 1999https://doi.org/10.1021/ja991040+Copyright © 1999 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views169Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (41 KB) Get e-AlertsSUBJECTS:Carbene compounds,Hydride transfer,Monomers,Nutrition,Organic compounds Get e-Alerts
Characterization of tissue from ultrasound images (1988)

The application of a procedure for classifying tissue types from unlabeled acoustic measurements using unsupervised analysis is reviewed and evaluated. Unsupervised learning techniques are applied to the problems of detecting tumors within an organ and of discriminating between tissue types of two neighboring organs such as the liver and the kidney.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Development of a Mid-infrared CW Optical Parametric Oscillator Based on Fan-out Grating MgO:PPLN Pumped at 1064 nm (2019)

We report development of a frequency-stabilized mid-infrared continuous-wave (cw) optical parametric oscillator (OPO) based on a fan-out grating MgO:PPLN crystal pumped at 1064 nm. The OPO resonator was designed as a pump-enhanced standing-wave cavity that resonates to the pump and signal beams. To realize stable operation of the OPO, we applied a modified Pound-Drever-Hall technique, which is a well-known method for powerful laser frequency stabilization. Tuning a poling period of the fan-out grating of the crystal allows wavelength-tunable OPO outputs from 1510 nm to 1852 nm and from 2500 nm to 3600 nm for signal and idler beams, respectively. At the idler wavelengths of 2500 nm, 3000 nm and 3500 nm, we achieved more than 50 mW of output powers at a pumping power of 1.1 W. The long-term stability of the OPO was confirmed by recording the power and wavelength variations of the idler for an hour.
EU FP7 INFSO-ICT-247223 ARTIST4G, D6.1 First feedback on implementation aspects connected to the selected innovations (2011)

This deliverable will enable an early feedback on the implemented schemes, such as implicit assumptions not considered before, or issues connected to robustness, complexity etc., that might require a refinement of the schemes in WP1-WP3.
Short-term ocular dominance changes in human V1. (2015)

Ocular dominance describes the contribution of each eye to binocular vision. This balance is disrupted in some clinical conditions such as amblyopia. It has been shown psychophysically that short-term monocular deprivation shifts the equilibrium towards the occluded eye (1). In this study, we wanted to investigate the cortical mechanism underlying this phenomenon using magnetoencephalography (MEG). Subjects were presented with monocular and dichoptic stimuli using a frequency tagging paradigm to identify the input coming from each eye. Three 10-minute blocks of MEG recordings were followed by 2.5 hours of monocular deprivation. Immediately after removal of the patch, another three consecutive blocks were recorded followed by a final recording 45 min post deprivation. Immediately following the removal of the patch, we observed an increase in power of the response from the occluded eye as early as in V1, and reflected in the response of subsequent brain areas as well. At the same time, the power of the response from the undeprived eye was reduced. The pre-deprivation ocular power distribution was achieved again at the 45 min post-deprivation recording. The power redistribution was observed both monocularly and dichoptically, but was more pronounced on dichoptic recording. We also observed an increase in variability of the response from the occluded eye post-deprivation. In conclusion, short-term monocular deprivation perturbes the binocular equilibrium as measured psychophysically. We were able to observe a physiological correlate of this perturbation in area V1 of the visual cortex with MEG. The change in V1 neuronal population activity observed here might be a direct consequence of the underlying plasticity occurring in the brain. Meeting abstract presented at VSS 2015
Mg2+ modulates membrane lipids in vascular smooth muscle: a link to atherogenesis (1997)

Epidemiological studies associate low dietary magnesium intake with an increased incidence of ischemic heart disease and sudden cardiac death. We have used proton-magnetic resonance (1H-NMR) techniques and Mg2+-selective electrodes to monitor changes in lipid extracts of aortic and cerebrovascular smooth muscle as extracellular ionized magnesium ion concentration ([Mg2+]o) is lowered. We have found that, within the pathophysiological range of Mg2+ concentrations, fatty acid chain length and double bond content are progressively reduced as [Mg2+]o is lowered. In contrast, the plasmalogen content is progressively increased. A concomitant decrease in fatty acid chain length and double bonds indicates oxidation of double bonds resulting in truncation of the fatty acids. A decrease in lipid oxidation in the presence of elevated Mg2+ could contribute to the apparent protective role of increased Mg2+ intake on vascular function in humans.
Cervical sarcomas: An analysis of treatment and outcome (2005)

5178 Background: Cervical sarcomas are exceedingly rare neoplasms associated with a poor prognosis. The objective of this study was to examine the treatment and outcome of women with cervical sarcomas. Methods: A hospital based tumor registry was searched to identify all patients with cervical sarcomas treated between 1986 and 2003. The medical records of all patients were reviewed. All pathologic specimens were reviewed by a single pathologist. Results: Among 1583 patients with cervical cancer, 11 cervical sarcomas were identified. Three patients were excluded after review found the histology to be inconsistent with sarcoma (2 poorly differentiated carcinomas, 1 sarcomatoid carcinoma). Cervical sarcomas thus accounted for 0.005% of all cervical tumors. The mean age of the 8 patients was 54 years. All initially presented with vaginal bleeding. A cervical mass was noted in all 8 patients, the mean size was 5.1 cm. The lesions were clinically staged as IB1 (2), IB2 (4), IIIA (1), and IIIB (1). Five of the tumors were carcinosarcomas, of which 3 were heterologous and 2 homologous. Other histologies included sarcoma NOS (12.5%), leiomyosarcoma (12.5%), and endometrial stromal sarcoma (12.5%). Initial treatment included surgery in 5 patients, radiation in 2 and chemoradiation in 1. Six (75%) patients were treated with curative intent, 5 received adjuvant therapy. While both patients treated palliatively died from progressive disease, the other 6 patients remain alive after a mean follow-up of 2.5 years. Two patients have recurred. One patient underwent a thoracotomy for an isolated pulmonary metastasis and is alive with no evidence of disease. The second patient developed pulmonary metastases and is alive eight months after recurrence. No locoregional recurrences have been noted. Conclusions: Cervical sarcomas are rare neoplasms. Most patients present with vaginal bleeding and a palpable cervical mass. While the optimal management of these tumors is uncertain, aggressive primary therapy can result in prolonged survival and cure. In this series all patients treated with curative intent were alive at the time of last follow-up. No significant financial relationships to disclose.
Investigation of Mechanoresponsive Behaviors of Human Embryonic Stem Cells Using Microfabricated Elastomeric Post Arrays (2012)

Much effort has been recently directed to investigate how soluble factors in the local cellular microenvironment of embryonic stem cells (ESCs) regulate their fate decisions [1]; however, effects of mechanical signals in the local cellular microenvironment on the fates of ESCs are still not yet well understood. Early experimental evidence established in recent years has shown that mechanical signals and external forces experienced through interactions with extracellular matrix (ECM) mechanics can play critical roles in regulating survival, proliferation and differentiation of ESCs. However, there is still limited knowledge of how mechanical signals in the local cellular microenvironment regulate the fate decisions of human ESCs (hESCs), and advancing such knowledge will be critical for both fundamental understanding and clinical applications of hESCs. This work was thus set to explicitly investigate the mechanosensitive properties of hESCs.
Statistical Analysis of Second Order Differential Power Analysis. (2010)

Second Order Differential Power Analysis (2ODPA) is a powerful side channel attack that allows an attacker to bypass the widely used masking countermeasure. To thwart 2ODPA, higher order masking may be employed but it implies an non-negligible overhead. In this context, there is a need to know how efficient a 2O-DPA can be, in order to evaluate the resistance of an implementation that uses first order masking and, possibly, some hardware countermeasures. Different methods of mounting a practical 2O-DPA attack have been proposed in the literature. However, it is not yet clear which of these methods is the most efficient. In this paper, we give a formal description of the higher order DPA that are mounted against software implementations. We then introduce a framework in which the attack efficiencies may be compared. The attacks we focus on involve the combining of several leakage signals and the computation of correlation coefficients to discriminate the wrong key hypotheses. In the second part of this paper, we pay particular attention to 2O-DPA that involves the product combining or the absolute difference combining. We study them under the assumption that the device leaks the Hamming weight of the processed data together with an independent gaussian noise. After showing a way to improve the product combining, we argue that in this model the product combining is more efficient not only than absolute difference combining, but also than all the other combining techniques proposed in the literature.
Knowledge-guided Self-supervised Learning for estimating River-Basin Characteristics. (2021)

Machine Learning is being extensively used in hydrology, especially streamflow prediction of basins/watersheds. Basin characteristics are essential for modeling the rainfall-runoff response of these watersheds and therefore data-driven methods must take into account this ancillary characteristics data. However there are several limitations, namely uncertainty in the measured characteristics, partially missing characteristics for some of the basins or unknown characteristics that may not be present in the known measured set. In this paper we present an inverse model that uses a knowledge-guided self-supervised learning algorithm to infer basin characteristics using the meteorological drivers and streamflow response data. We evaluate our model on the the CAMELS dataset and the results validate its ability to reduce measurement uncertainty, impute missing characteristics, and identify unknown characteristics.
Local structure around Mn in Mn containing ZnO nanocrystals (2007)

Abstract Among the diluted magnetic semiconductors of current interest, especially ZnO is experiencing a renaissance with the incorporation of Mn because of the recent predictions from theory. We have obtained local structure information from X‐ray Absorption Spectroscopy (XAS) complementing previous electron paramagnetic resonance (EPR) studies on Mn in ZnO nanocrystals and Zn(OH) 2 . Mn is found to be incorporated substitutionally into the ZnO nanocrystals with a sizeable distortion as compared to the regular ZnO lattice structure. Depending on the preparation of the nanocrystals Mn is found in the ZnO core as well as in a Zn(OH) 2 surface shell with a fraction which decreases upon annealing as the shell disintegrates forming additional ZnO. No indications for Mn clusters were found. (© 2007 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)
INDEPENDENCE OF RESPONSE FORCE AND REINFORCEMENT RATE ON CONCURRENT VARIABLE‐INTERVAL SCHEDULE PERFORMANCE (1982)

Five pigeons were trained over 43 experimental conditions on a variety of concurrent variable-interval schedules on which the forces required on the response keys were varied. The results were well described by the generalized matching law with log reinforcement ratios and log force ratios exerting independent (noninteractive) effects on preference. A further analysis using the Akaike criterion, an information-theoretic measure of the efficiency of a model, showed that overall reinforcement rate and overall force requirement did not affect preference. Unlike reinforcement rate changes, force requirement increases did not change the response rate on the alternate key, and an extension of Herrnstein's absolute response rate function for force variation on a single variable-interval schedule is suggested.
Mesoporous Sulfonated Carbon Materials Prepared by Spray Pyrolysis (2015)

Abstract A one‐step approach was developed for the production of mesoporous sulfonated carbon materials by means of an aerosol synthesis. Nebulizing a clear aqueous solution of sucrose and sulfuric acid through a heated oven leads to subsequent dehydration, carbonization and sulfonation of the carbohydrate structure, in less than two seconds residence time. Acid site concentrations ranging from 0.1 to 0.6 mmol g −1 can be obtained. Porosity can easily be introduced via salt templating, and can be adjusted by varying the loading and type of salt used. The highest surface area was obtained with Li 2 SO 4 , giving a BET surface area of 506 m 2 g −1 and a mesopore size distribution between 2 and 8 nm. Fructose dehydration and inulin hydrolysis showed that the porous materials synthesized by salt templating are more active than the bulk ones, especially for inulin hydrolysis, for which the initial activity is enhanced by a factor of seven, making these materials competitive with the most active commercial resins.
Ferroelectric oxide slot waveguide electro-optic modulator on Silicon (2016)

13-18 february 2016