gebhart/patrepeval huggingface dataset:
Wertigkeit von Patient-Reported Outcome Measures zur Bewertung des Versorgungsvorteils der Sprachprozessorumversorgung bei Patient/-innen mit Cochleaimplantaten (2023)

There was a significant improvement in audiologically measurable and subjectively reflected speech understanding and patient satisfaction after the upgrade. In patients with only a small improvement in audiologically measurable speech understanding, the subjective benefit should also be assessed with validated measurement instruments in order to justify an upgrade to the payers in the health sector.
Self-assembled photosystem-I biophotovoltaics on nanostructured TiO2 and ZnO (2012)

The abundant pigment-protein membrane complex photosystem-I (PS-I) is at the heart of the Earth's energy cycle. It is the central molecule in the "Z-scheme" of photosynthesis, converting sunlight into the chemical energy of life. Commandeering this intricately organized photosynthetic nanocircuitry and re-wiring it to produce electricity carries the promise of inexpensive and environmentally friendly solar power. We here report that dry PS-I stabilized by surfactant peptides functioned as both the light-harvester and charge separator in solar cells self-assembled on nanostructured semiconductors. Contrary to previous attempts at biophotovoltaics requiring elaborate surface chemistries, thin film deposition, and illumination concentrated into narrow wavelength ranges the devices described here are straightforward and inexpensive to fabricate and perform well under standard sunlight yielding open circuit photovoltage of 0.5 V, fill factor of 71%, electrical power density of 81 µW/cm(2) and photocurrent density of 362 µA/cm(2), over four orders of magnitude higher than any photosystem-based biophotovoltaic to date.
Resolution properties of a prototype continuous miniature crystal element (cMiCE) scanner (2010)

Continuous miniature crystal element (cMiCE) detectors are a potentially lower cost alternative to high resolution discrete crystal PET detector designs. We report on performance characteristics of a prototype PET scanner consisting of two cMiCE detector modules. Each cMiCE detector is comprised of a 50 mm by 50 mm by 8 mm LYSO crystal coupled to a 64 channel multi-anode PMT. The cMiCE detectors use a statistics-based positioning method based upon the maximum likelihood method for event positioning. In addition, cMiCE detectors can provide some depth of interaction event positioning information. For the prototype scanner, the cMiCE detectors were positioned across from one another on a horizontal gantry with a detector spacing of 10.1 cm. Full tomographic data were collected by placing the object to be imaged on a rotating stage. Data were collected in a step and shoot fashion with 6 degree angular steps. Data were collected for point sources placed at 1, 5, 10 and 15 mm radial offset from the center of the imaging field of view. Data were binned using single slice rebinning and reconstructed using filtered back projection with a ramp filter. The average image resolutions for X (radial), Y (transverse) and Z (axial) were 1.09 mm, 0.99 mm, 1.25 mm FWHM, respectively. The initial imaging results from a prototype cMiCE imaging system demonstrate the outstanding image resolution performance than can be achieved using cMiCE detectors.
High oxidation-state compounds containing hydrazine and hydrazido ligands bound to a W(N-2,6-C6H3-iso-Pr2)[2,6-NC5H3(CH2NTosyl)2] core (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHigh oxidation-state compounds containing hydrazine and hydrazido ligands bound to a W(N-2,6-C6H3-iso-Pr2)[2,6-NC5H3(CH2NTosyl)2] coreShiang Cai and Richard R. SchrockCite this: Inorg. Chem. 1991, 30, 22, 4105–4106Publication Date (Print):October 1, 1991Publication History Published online1 May 2002Published inissue 1 October 1991https://pubs.acs.org/doi/10.1021/ic00022a002https://doi.org/10.1021/ic00022a002research-articleACS PublicationsRequest reuse permissionsArticle Views132Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
1405: Biopsy Gleason Upgrading by a Tertiary Referral Center is Associated with Increased Incidence of Lymph Node Involvement: Implications for Pelvic Lymphadenectomy Decision Models (2007)

You have accessJournal of UrologyModerated Poster 42, Tuesday, May 22, 2007, 1:00 - 3:00 pm1 Apr 20071405: Biopsy Gleason Upgrading by a Tertiary Referral Center is Associated with Increased Incidence of Lymph Node Involvement: Implications for Pelvic Lymphadenectomy Decision Models David S. Sharp, Theresa M. Koppie, Karim Touijer, James A. Eastham, Peter T. Scardino, and Bertrand Guillonneau David S. SharpDavid S. Sharp More articles by this author , Theresa M. KoppieTheresa M. Koppie More articles by this author , Karim TouijerKarim Touijer More articles by this author , James A. EasthamJames A. Eastham More articles by this author , Peter T. ScardinoPeter T. Scardino More articles by this author , and Bertrand GuillonneauBertrand Guillonneau More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)31606-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1405: Biopsy Gleason Upgrading by a Tertiary Referral Center is Associated with Increased Incidence of Lymph Node Involvement: Implications for Pelvic Lymphadenectomy Decision Models." The Journal of Urology, 177(4S), p. 463 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 177Issue 4SApril 2007Page: 463 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information David S. Sharp More articles by this author Theresa M. Koppie More articles by this author Karim Touijer More articles by this author James A. Eastham More articles by this author Peter T. Scardino More articles by this author Bertrand Guillonneau More articles by this author Expand All Advertisement PDF downloadLoading ...
Large Extinction Ratio Electrowetting Optical Shutter (2016)

We demonstrate a large extinction ratio optical shutter using total internal reflection with an electrowetting device. An on-off ratio of greater than 60 dB was measured. The device shows promise for chip-scale atomic-clocks and gyroscopes.
MR imaging of knee hyaline cartilage: Evaluation of two‐ and three‐dimensional sequences (1993)

Magnetic resonance (MR) imaging of cadaveric knees was performed to determine optimal sequences for visualization of hyaline cartilage. Full-thickness cartilage lesions ranging in diameter from 1 to 5 mm and a partial-thickness cartilage lesion 15 mm in diameter were created in the femoral articular surfaces of three cadaveric knees. The knees were then imaged with a 1.5-T imager with various two-dimensional and high-resolution three-dimensional (3D) techniques. After imaging, the knee specimens were sectioned for evaluation. Measurements of cartilage thickness in fast spin-echo images correlated best with those in the gross specimen. Diffuse areas of cartilage thinning were also most accurately identified with fast spin-echo images. Small, focal cartilage defects were best delineated in 3D SPGR (spoiled GRASS [gradient-recalled acquisition in the steady state]) images.
The cellular basis for the induction of antigen‐specific T8 suppressor cells (1986)

The cellular basis for the generation of antigen-specific T8 suppressor cells with high doses of antigen has been studied. We separated the T4 subset of human T cells into T4+2H4+ and T4+2H4- subpopulations with a recently developed monoclonal anti-2H4 antibody. T8 cells could be consistently activated to suppress a primary anti-2,4-dinitrophenyl (DNP) antibody response in vitro with unfractionated T4 cells or with the T4+2H4+ subset but not the T4+2H4- subset. In contrast, the T4+2H4- subset functioned as the helper inducer for the anti-DNP antibody response. With keyhole limpet hemocyanin (KLH)-stimulated T4+2H4+ cells we could efficiently induce antigen-specific suppressor activity of fresh T8 cells. In contrast, the T4+2H4+ subset could not effect suppression in the absence of T8 cells. Our findings indicate that the T4+2H4+ subset of human T cells is the suppressor inducer of specific T8 cells in an antigen-specific DNP-KLH system.
Homologous Pairing Promoted by the Human Rad52 Protein (2001)

The Rad52 protein, which is unique to eukaryotes, plays important roles in the Rad51-dependent and the Rad51-independent pathways of DNA recombination. In the present study, we have biochemically characterized the homologous pairing activity of the HsRad52 protein (Homo sapiens Rad52) and found that the presynaptic complex formation with ssDNA is essential in its catalysis of homologous pairing. We have identified an N-terminal fragment (amino acid residues 1-237, HsRad52(1-237)) that is defective in binding to the human Rad51 protein, which catalyzed homologous pairing as efficiently as the wild type HsRad52. Electron microscopic visualization revealed that HsRad52 and HsRad52(1-237) both formed nucleoprotein filaments with single-stranded DNA. These lines of evidence suggest the role of HsRad52 in the homologous pairing step of the Rad51-independent recombination pathway. Our results reveal the striking similarity between HsRad52 and the Escherichia coli RecT protein, which functions in a RecA-independent recombination pathway.
Reconstructing approximate tree metrics (2007)

We introduce a novel measure called ε-four-pointscondition (ε-4PC), which assigns a value ε ∈ [0,1] to every metric space quantifying how close the metric is to a tree metric. Data-sets taken from real Internet measurements indicate remarkable closeness of Internet latencies to tree metrics based on this condition. We study embeddings of ε-4PC metric spaces into trees and prove tight upper and lower bounds. Specifically, we show that there are constants c1 and c2 such that, (1) every metric (X,d) which satisfies the ε-4PC can be embedded into a tree with distortion (1+ε)c1log|X|, and (2) for every ε ∈: [0,1] and any number of nodes, there is a metric space (X,d) satisfying the ε-4PC that does not embed into a tree with distortion less than (1+ε)c2log|X|. In addition, we prove a lower bound on approximate distance labelings of ε-4PC metrics, and give tight bounds for tree embeddings with additive error guarantees.
Novel and simple table-based HBT large-signal model (2007)

A novel and simple table-based HBT large-signal model is presented. All parameters are tabulated as two- parameter functions. The model accounts for self-heating by allowing ideality factors and saturation currents to be functions of the dissipated power. Small-signal model parameters, systematically extracted from RF S-parameter measurements, are used in conjunction with DC measurements to extract static model parameters characterizing the forward active regime of operation. Such a procedure ensures consistency between small-signal and DC simulations. A 1x10 mum <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> emitter-area InGaP/GaAs HBT device is used to validate the proposed model.
Kramers-Kronig relation between n2 and two-photon absorption (1990)

Nonlinear refractive index and two-photon absorption measurements on semiconductors show that the bound electronic nonlinearity can be calculated from two-photon absorption dispersion via a simple Kramers- Kronig analysis. This analysis shows n2 changing from positive to negative as the photon energy approaches the band-gap energy, consistent with observations. Additionally, this simple calculation, which assumes two parabolic bands, gives good agreement with measured values of n2 in wide-gap dielectrics that are 2 to 3 orders of magnitude smaller than in semiconductors.
Expression of Interleukin-18 in Murine Contact Hypersensitivity (1998)

In this study, we made a mouse model for contact hypersensitivity (CH) using oxazolone as a contact allergen and examined the expression of interleukin-18 (IL-18) in the diseased skin sites at both mRNA and protein levels. In the kinetic study by semiquantitative RT-PCR, IL-18 mRNA was constitutively produced in normal murine skin but increased significantly at 12 h and peaked at 24 h in the ear skin of CH mice. A positive correlation was confirmed between the IL-18 mRNA signal and CH, as measured by mouse ear swelling response. Histologically, in situ hybridization showed that the IL-18 mRNA signal was weakly observed in the dermis but not the epidermis of normal skin, whereas the IL-18 mRNA signal was found intensively in the dermis, particularly in inflammatory cell areas. Using IL-18-specific antibody immunostaining, it was further found that IL-18 protein production had a histologic location similar to that of IL-18 mRNA in both normal and CH mice. The present study suggests that IL-18 may be implicated in the pathogenesis of murine CH.
Synthesis and Structures of Polymeric Mn, Co, Cu, and Zn Complexes of 3-Diphenylamino-4-hydroxycyclobut-3-ene-1,2-dione (Diphenylaminosquarate) and of the Salt [Ni(H2O)6][(C6H5)2NC4O3]2·2H2O (2000)

Reaction of M(NO3)2.xH2O (M = Mn, Co, Ni, Cu, Zn) with 3-diphenylamino-4-hydroxycyclobut-3-ene-1,2-dione (diphenylaminosquarate) produces the neutral polymeric species (M[mu-(C6H5)2NC4O3]2[H2O]2)n [M = Mn (1), Cu (2)]; (M[mu-(C6H5)2NC4O3][(C6H5)2NC4O3][H2O]3)n [M = Co (3), Zn (4)]; and in the case of Ni, the salt [Ni(H2O)6][(C6H5)2NC4O3]2.2H2O (5). Complexes 1 and 2 are isomorphous and crystallize in the monoclinic space group P2(1)/c with, for 1, a = 13.138(1) A, b = 10.900(2) A, c = 9.269(2) A, beta = 96.07(1) degrees, and Z = 2. Complexes 3 and 4 are also isomorphous and crystallize in the space group P2(1)/c with, for 3, a = 13.211(1) A, b = 11.038(1) A, c = 18.748(1) A, beta = 97.75(1) degrees, and Z = 4. The nickel salt, 5, crystallizes in the triclinic space group P1 with a = 6.181(1) A, b = 9.417(1) A, c = 15.486(1) A, alpha = 101.37(1) degrees, beta = 95.51(1) degrees, gamma = 107.57(1) degrees, and Z = 1. In 1 and 2, the metal coordination is octahedral, comprising four mu-1,3-bridging diphenylaminosquarate ligands and two trans aqua ligands. In 3 and 4, the metal coordination is again octahedral, comprising two mu-1,3-bridging and one pendant diphenylaminosquarate ligands, the octahedron being completed by three aqua ligands in a meridional configuration. In 5, the hexaaquanickel(II) ion is linked by O-H...O hydrogen bonds to a pair of diphenylaminosquarate anions. These anion-cation units are linked via included water molecules to form hydrogen-bonded chains. The diphenylaminosquarate ligands in the polymeric complexes 1-4 display multiple-bond localization, a feature which is absent in 5. Complex 1 exhibits weak antiferromagnetic coupling, whereas 2 shows no significant magnetic interactions.
Importance of timing of radioimmunotherapy after granulocyte colony-stimulating factor administration for peripheral blood stem cell harvest. (1999)

Nine radioimmunotherapy (RAIT)-naive patients with medullary thyroid cancer received high doses of 131I-MN-14 F(ab)2 anti-carcinoembryonic antigen monoclonal antibody (232-486 mCi), five in combination with bone marrow harvest, without prior granulocyte colony stimulating factor (G-CSF) injections (group 1) and the other four using peripheral blood stem cell harvest (PBSCH) preceded by G-CSF administration of 10 microg/kg per day for 5 days for stem cell mobilization, 6-8 days before RAIT (group 2). The amounts of radioactivity (mCi) given in both groups were similar (312 +/- 93 versus 424 +/- 65; P = NS). The percent platelet loss at nadir, duration of grade 4 thrombocytopenia, and time to complete recovery (TTCR, measured from the day of treatment), were 83 +/- 17%, 2.5 +/- 0.7 days, and 45 +/- 8 days in group 1, respectively, compared with 88 +/- 6%, 3.0 +/- 2.6 days, and 50 +/- 24 days in group 2 (P = NS), respectively. In contrast, the percent WBC loss at nadir, duration of grade 4 leukopenia, and TTCR of WBCs were 72 +/- 12%, 0.0 +/- 0.0 day, and 42 +/- 12 days in group 1, respectively, compared with 93 +/- 3%, 8.0 +/- 3.6 days, and 263 +/- 136 days in group 2, respectively (P < 0.02, 0.03, and 0.05 for differences of percent loss, duration of nadir, and TTCR, respectively). The difference in WBC toxicity after RAIT with bone marrow harvest and PBSCH is thought to be due to the administration of G-CSF for stem cell mobilization within 1 week before RAIT, which may sensitize the "endogenous" granulocyte precursors to subsequent RAIT. Preclinical data of RAIT in mice showed that the time of G-CSF administration before RAIT is critical: increased WBC toxicity was seen in mice given RAIT 3 or 7 days after a 5-day course of G-CSF (81 and 57% WBC loss, respectively) compared with those given no G-CSF or G-CSF 10 or 14 days before RAIT (45-50%) WBC loss). In conclusion, our data indicate that the timing of RAIT after the administration of G-CSF for PBSCH may influence WBC toxicity and recovery after this treatment and may have important implications on the design of high-dose RAIT trials combined with PBSCH.
Gold-Coated NIR Stents in Porcine Coronary Arteries (2001)

Gold coatings enhance the radiopacity of steel stents, but not without effects on vascular repair. Material effects predominate and can be abrogated by heating coated stents to alter surface finish and material purity. Clinical results may suffer unless consideration is given to material and physical effects of gold.
Motion picture watermarking via quantization of pseudo-random linear statistics (2005)

In this paper, we propose a semi-blind video watermarking scheme, where we use pseudo-random robust semi-global features of video in the spatially wavelet transform domain. We design the watermark sequence via solving an optimization problem, such that the features of the mark-embedded video are the quantized versions of the features of the original video. We use a novel approach in generating the watermark such that the temporal correlation within the video frames is reflected on the generated watermark. This is achieved by i) using a special weight distribution along the time axis ii) modifying the regularization step to reflect the temporal characteristic of the host. We experimentally show the robustness of our algorithm against temporal filtering attacks and at the same time show a common weakness in 3D transform based video mark embedding methods.
Supported lipid bilayers microarrays onto a surface and inside microfluidic channels (2006)

We present simple soft lithographic methods for patterning supported lipid bilayer (SLB) membranes onto a surface and inside microfluidic channels. Micropatterns of polyethylene glycol (PEG)-based polymers were fabricated on glass substrates by microcontact printing or capillary molding. The patterned PEG surfaces have shown 97±0.5% reduction in lipid adsorption onto two dimensional surfaces and 95±1.2% reduction inside microfluidic channels in comparison to glass control. Atomic force microscopy measurements indicated that the deposition of lipid vesicles led to the formation of SLB membranes by vesicle fusion due to hydrophilic interactions with the exposed substrate. Furthermore, the functionality of the patterned SLBs was tested by measuring the binding interactions between biotin (ligand)-labeled lipid bilayer and streptavidin (receptor). SLB arrays were fabricated with spatial resolution down to ~500 nm on flat substrate and ~1 μm inside microfluidic channels, respectively.
Highly permeable, transparent and degradable membranes for tissue scaffolding (2013)

Extended abstract of a paper presented at Microscopy and Microanalysis 2013 in Indianapolis, Indiana, USA, August 4 – August 8, 2013.
A 1.5-V 550-μW 176 x 144 autonomous CMOS active pixel image sensor (2003)

This paper addresses the development of a micropower 176/spl times/144 CMOS active pixel image sensor that dissipates one to two orders of magnitude less power than current state-of-the-art CMOS image sensors. The chip operates from a 1.5-V voltage source and the power consumption measured for the chip running from an internal 25.2-MHz clock yielding 30 frames per second is about 550 /spl mu/W. This amount enables the sensor to run from a watch battery. In order to achieve design goals, a low-power sensor design methodology is applied throughout the design process from system-level to process-level, while realizing the performance to satisfy the design specification. As an autonomous sensor, it can be operated with only three pads [GND, VDD (1.2-1.7 V), DATAOUT]. The die occupies 4 mm/sup 2/ of silicon.
Supplementary Table 2 from The Transcription Factor ZNF217 Is a Prognostic Biomarker and Therapeutic Target during Breast Cancer Progression (2023)

&lt;p&gt;PDF file - 46K, Gene ontology for microarray gene sets. List of gene ontology (GO) terms from the microarray gene expression datasets of primary MECs � Znf217 using DAVID software&lt;/p&gt;
OVINE KNEE KINEMATICS AND CONTACT PRESSURES OF A NOVEL FIBRE MATRIX-REINFORCED HYDROGEL TOTAL MENISCUS REPLACEMENT (2023)

No proven long-term joint-preserving treatment options exist for patients with irreparable meniscal damage. This study aimed to assess gait kinematics and contact pressures of novel fibre-matrix reinforced polyvinyl alcohol-polyethylene glycol (PVA-PEG) hydrogel meniscus implanted ovine stifle joints against intact stifles in a gait simulator. The gait simulator controlled femoral flexion-extension and applied a 980N axial contact force to the distal end of the tibia, whose movement was guided by the joint natural ligaments (Bartolo; ORS 2021;p1657- LB). Five right stifle joints from sheep aged &gt;2 years were implanted with a PVA-PEG total medial meniscus replacement, fixed to the tibia via transosseous tunnels and interference screws. Implanted stifle joint contact pressures and kinematics in the simulator were recorded and compared to the intact group. Contact pressures on the medial and lateral condyles were measured at 55° flexion using Fujifilm Prescale Low Pressure film inserted under the menisci. 3D kinematics were measured across two 30 second captures using the Optotrak Certus motion-tracking system (Northern Digital Inc.). Medial peak pressures were not significantly different between the implanted and intact groups (p&gt;0.4), while lateral peak pressures were significantly higher in the implanted group (p&lt;0.01). Implanted stifle joint kinematics in the simulator did not differ significantly from the intact baseline (p&gt;0.01), except for in distraction-compression (p&lt;0.01). Our findings show that the fibre-matrix reinforced PVA-PEG hydrogel meniscal replacement restored the medial peak contact pressures. Similar to published literature (Fischenich; ABE 2018;46(11):1–12), the lateral peak pressures in the implanted group were higher than the intact. Joint kinematics were similar across groups, with slightly increased internal-external rotation in the implanted group. These findings highlight the effectiveness of the proposed approach and motivate future work on the development of a total meniscal replacement.