gebhart/patrepeval huggingface dataset:
Bithiophene-Imide-Based Polymeric Semiconductors for Field-Effect Transistors: Synthesis, Structure−Property Correlations, Charge Carrier Polarity, and Device Stability (2011)

Developing new high-mobility polymeric semiconductors with good processability and excellent device environmental stability is essential for organic electronics. We report the synthesis, characterization, manipulation of charge carrier polarity, and device air stability of a new series of bithiophene-imide (BTI)-based polymers for organic field-effect transistors (OFETs). By increasing the conjugation length of the donor comonomer unit from monothiophene (P1) to bithiophene (P2) to tetrathiophene (P3), the electron transport capacity decreases while the hole transport capacity increases. Compared to the BTI homopolymer P(BTimR) having an electron mobility of 10(-2) cm(2) V(-1) s(-1), copolymer P1 is ambipolar with balanced hole and electron mobilities of ∼10(-4) cm(2) V(-1) s(-1), while P2 and P3 exhibit hole mobilities of ∼10(-3) and ∼10(-2) cm(2) V(-1) s(-1), respectively. The influence of P(BTimR) homopolymer M(n) on film morphology and device performance was also investigated. The high M(n) batch P(BTimR)-H affords more crystalline film microstructures; hence, 3× increased electron mobility (0.038 cm(2) V(-1) s(-1)) over the low M(n) one P(BTimR)-L (0.011 cm(2) V(-1) s(-1)). In a top-gate/bottom-contact OFET architecture, P(BTimR)-H achieves a high electron mobility of 0.14 cm(2) V(-1) s(-1), only slightly lower than that of state-of-the-art n-type polymer semiconductors. However, the high-lying P(BTimR)-H LUMO results in minimal electron transport on exposure to ambient. Copolymer P3 exhibits a hole mobility approaching 0.1 cm(2) V(-1) s(-1) in top-gate OFETs, comparable to or slightly lower than current state-of-the-art p-type polymer semiconductors (0.1-0.6 cm(2) V(-1) s(-1)). Although BTI building block incorporation does not enable air-stable n-type OFET performance for P(BTimR) or P1, it significantly increases the OFET air stability for p-type P2 and P3. Bottom-gate/top-contact and top-gate/bottom-contact P2 and P3 OFETs exhibit excellent stability in the ambient. Thus, P2 and P3 OFET hole mobilities are almost unchanged after 200 days under ambient, which is attributed to their low-lying HOMOs (>0.2 eV lower than that of P3HT), induced by the strong BTI electron-withdrawing capacity. Complementary inverters were fabricated by inkjet patterning of P(BTimR)-H (n-type) and P3b (p-type).
A Study of 6H-Seeded 4H-SiC Bulk Growth by PVT (2005)

4H-SiC crystals were grown using the seeded sublimation technique (modified Lely technique) in the temperature range of 1950-2200°C. The nucleation of 4H-SiC on 6HSiC has been optimized and 4H-SiC crystals of 1cm thickness were grown using 6H-SiC seeds. a-face and c-face wafers obtained from the grown boules were characterized by KOH etching, X-ray diffraction, and Raman scattering studies. Complete polytypic homogeneity of 4H SiC was obtained during growth and it was found that the 6H to 4H transition occurs in three ways: 1) without a transition layer, 2) with thick 6H-SiC layer growth, and 3) with traces of 3C SiC inclusions. The crown regions of the grown crystals exhibit an X-ray rocking curve width of 21 arcsecs.
Annotation of the Asian Citrus Psyllid Genome Reveals a Reduced Innate Immune System (2016)

Citrus production worldwide is currently facing significant losses due to citrus greening disease, also known as Huanglongbing. The citrus greening bacteria, Candidatus Liberibacter asiaticus (CLas), is a persistent propagative pathogen transmitted by the Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Liviidae). Hemipterans characterized to date lack a number of insect immune genes, including those associated with the Imd pathway targeting Gram-negative bacteria. The D. citri draft genome was used to characterize the immune defense genes present in D. citri. Predicted mRNAs identified by screening the published D. citri annotated draft genome were manually searched using a custom database of immune genes from previously annotated insect genomes. Toll and JAK/STAT pathways, general defense genes Dual oxidase, Nitric oxide synthase, prophenoloxidase, and cellular immune defense genes were present in D. citri. In contrast, D. citri lacked genes for the Imd pathway, most antimicrobial peptides, 1,3-β-glucan recognition proteins (GNBPs), and complete peptidoglycan recognition proteins. These data suggest that D. citri has a reduced immune capability similar to that observed in A. pisum, P. humanus, and R. prolixus. The absence of immune system genes from the D. citri genome may facilitate CLas infections, and is possibly compensated for by their relationship with their microbial endosymbionts.
Radiolabeling of monoclonal antibodies and fragments with technetium and rhenium (1992)

ADVERTISEMENT RETURN TO ISSUEArticleNEXTRadiolabeling of monoclonal antibodies and fragments with technetium and rheniumGary L. Griffiths, David M. Goldenberg, Anastasia L. Jones, and Hans J. HansenCite this: Bioconjugate Chem. 1992, 3, 2, 91–99Publication Date (Print):March 1, 1992Publication History Published online1 May 2002Published inissue 1 March 1992https://pubs.acs.org/doi/10.1021/bc00014a001https://doi.org/10.1021/bc00014a001research-articleACS PublicationsRequest reuse permissionsArticle Views261Altmetric-Citations58LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Use of 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil as a novel antiviral agent for hepatitis B virus and Epstein-Barr virus (1995)

A novel anti-hepatitis B virus (anti-HBV) agent, 2'-fluoro-5-methyl-beta-L-arabinofuranosyluracil (L-FMAU), was synthesized and found to be a potent anti-HBV and anti-Epstein-Barr virus agent. Its in vitro potency was evaluated in 2.2.15 and H1 cells for anti-HBV and anti-Epstein-Barr virus activities, respectively. In vitro cytotoxicity in MT2, CEM, 2.2.15, and H1 cells was also assessed, and the results indicated high antiviral selectivities of L-FMAU in these cells.
Longitudinal noninvasive monitoring of transcription factor activation in cardiovascular regulatory nuclei using bioluminescence imaging (2008)

The ability to monitor transcription factor (TF) activation in the central nervous system (CNS) has the potential to provide novel information regarding the molecular mechanisms underlying a wide range of neurobiological processes. However, traditional biochemical assays limit the mapping of TF activity to select time points. In vivo bioluminescence imaging (BLI) has emerged as an attractive technology for visualizing internal molecular events in the same animal over time. Here, we evaluated the utility of BLI, in combination with virally mediated delivery of reporter constructs to cardiovascular nuclei, for monitoring of TF activity in these discrete brain regions. Following viral gene transfer of NF-kappaB-driven luciferase reporter to the subfornical organ (SFO), BLI enabled daily measurements of baseline TF activity in the same animal for 1 mo. Importantly, systemic endotoxin, a stimulator of NF-kappaB activity, induced dramatic and dose-dependent increases in NF-kappaB-dependent bioluminescence in the SFO up to 30 days after gene transfer. Cotreatment with a dominant-negative IkappaBalpha mutant significantly prevented endotoxin-dependent NF-kappaB activation, confirming the specificity of the bioluminescence signal. NF-kappaB-dependent luminescence signals were also stable and inducible 1 mo following delivery of luciferase reporter construct to the paraventricular nucleus or rostral ventrolateral medulla. Lastly, using targeted adenoviral delivery of an AP-1 responsive luciferase reporter, we showed similar baseline and endotoxin-induced AP-1 activity in these same brain regions as with NF-kappaB reporters. These results demonstrate that BLI, in combination with virally mediated gene transfer, is a powerful method for longitudinal monitoring and quantification of TF activity in targeted CNS nuclei in vivo.
New Magnetic Multilayer for a Direct On-chip EMI Shielding Layer on a Mold Substrate in the sub-100 MHz Frequency Range (2022)

A new type of metallic/magnetic multilayer system was investigated as a direct on-chip electromagnetic interference (EMI) shielding layer for the sub-100 MHz frequency range. It was found that a multilayer of [Cu (100 nm)/Ni-Fe-Cu-Mo (NFCM) (100 nm)]10/[Ta (5 nm)/NFCM (50 nm)]55/[Ta (5 nm)/NFCM (300 nm)]10 exhibited a high shielding effect at around 50 MHz for both glass and mold substrates. This structure also exhibited a better shielding effect at 170 kHz than the conventional magnetic shielding. These results are due to magneto-static interactions between multilayer units, which was evidenced by a hysteresis loop typical for a single-layer soft magnetic film. It is suggested that the coupling reduces the energy of the domain wall resonance and shifts the resonance peak to lower frequency. It was also found that substitution of CrTi layer for the Ta layer further improved the shielding effect in the lower frequency region. This multilayer system is a promising candidate for the direct-on-chip shielding layer covering the kHz to sub-100 MHz frequency range, which is suitable for application in power modules used for mobile devices and electric vehicles.
Xenopus oocyte K+ current. II. Adenylyl cyclase-linked receptors on follicle cells (1990)

Xenopus ovarian follicles consist of single large oocytes surrounded by a layer of small follicle cells that are coupled to the oocyte by gap junctions. Hyperpolarizing K+ currents can be detected in the oocytes of follicles stimulated with adenosine, isoproterenol, follicle-stimulating hormone (FSH), or microinjected adenosine 3',5'-cyclic monophosphate (cAMP). We show that cAMP accumulation can be detected in follicles incubated with the adenosine agonist 5'-N-ethylcarboxamidoadenosine (NECA), isoproterenol, or FSH, but only if forskolin and a phosphodiesterase inhibitor are also added. Treatment of follicles with collagenase has been reported to reduce, but usually not to eliminate, cAMP-activated K+ currents. In this study we show that collagenase treatment alone does not completely remove follicle cells or receptor-mediated cAMP accumulation measured in follicles. cAMP accumulation and cAMP-dependent K+ currents are both eliminated when the follicle cells are completely removed by a technique involving treatment of follicles with collagenase and hypertonic saline. Oocytes completely stripped of follicle cells fail to accumulate cAMP in response to receptor agonists and forskolin. Isolated follicle cells derived from single follicles (but without the oocyte present) accumulate cAMP in response to these drugs to an extent equivalent to the response seen in single intact follicles. Adenylyl cyclase-linked receptors of Xenopus follicles thus appear to be located exclusively on follicle cells. The data suggest that cAMP-dependent K+ currents, although measured in oocytes, may be generated in follicle cells which communicate with oocytes. Another possibility is that a high resting K+ conductance in follicle cells is communicated to oocytes via cAMP-sensitive gap junctions.
Solid‐state synthesis of multicomponent equiatomic rare‐earth oxides (2019)

Abstract Phase formation in multicomponent rare‐earth oxides is determined by a combination of composition, sintering atmosphere, and cooling rate. Polycrystalline ceramics comprising various combinations of Ce, Gd, La, Nd, Pr, Sm, and Y oxides in equiatomic proportions were synthesized using solid‐state sintering. The effects of composition, sintering atmosphere, and cooling rate on phase formation were investigated. Single cubic or monoclinic structures were obtained with a slow cooling of 3.3°C/min, confirming that rare‐earth oxides follow a different structure stabilization process than transition metal high‐entropy oxides. In an oxidizing atmosphere, both Ce and Pr induce a cubic structure, while only Ce plays that role in an inert or reducing atmosphere. Samples without Ce or Pr develop a single monoclinic structure. The structures formed at initial synthesis may be converted to a different one, when the ceramics are annealed in an additional atmosphere. Phase evolution of a five‐cation composition was also studied as a function of sintering temperature. The binary oxides used as raw materials completely dissolve into a single cubic structure at 1450°C in air.
Optical measurement of doping efficiency in poly(3-hexylthiophene) solutions and thin films (2015)

The doping mechanism of 2,3,5,6-tetrafluoro-7,7,8,8,-tetracyanoquinodimethane (F4TCNQ) doped poly(3-hexylthiophene) (P3HT) thin films and solutions is studied by UV-visible and IR absorption spectral analysis. We show that integer charge transfer between the two molecules is observed in this system with 63% of the dopants producing a fully transferred charge in thin film. The primary P3HT doped species in solution and thin film are shown to be bipolarons and polarons, respectively. The absorption signatures of polarons and bipolarons are identified and their cross sections are measured, which can be used to evaluate the influence of processing conditions on the density of impurity dopant-induced polarons in nominally ``neat'' P3HT films.
ChemInform Abstract: Microwave‐Promoted Transformations: Fast and Chemoselective N‐ Acylation of Amino Alcohols Using Catalytic Amounts of Dibutyltin Oxide. Influence of the Power Output and the Nature of the Acylating Agent on the Selectivity. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Competitive Partial Computation Offloading for Maximizing Energy Efficiency in Mobile Cloud Computing (2017)

In this paper, we newly model computation offloading competition when multiple clients compete with each other so as to reduce energy cost and improve computational performance. We consider two types of destination of offloading request, such as a cloudlet and a remote cloud. Here, the cloudlet consists of locally connected mobile terminals with low-latency and high bandwidth but suffering from task overload due to its limited computational capacity. On the other hand, the remote cloud has a high and stable capacity but the high latency. To facilitate the competition model, on the destination sides, we have designed an energy-oriented task scheduling scheme, which aims to maximize the welfare of clients in terms of energy efficiency. Under this proposed job scheduling, as a joint consideration of the destination and client sides, competition behavior among multiple clients for optimal computation offloading is modeled and analyzed as a non-cooperative game by considering a trade-off between different types of destinations. Based on this game-theoretical analysis, we propose a novel energy-oriented weight assignment scheme in the mobile terminal side to maximize mobile terminal energy efficiency. Finally, we show that the proposed scheme converges well to a unique equilibrium and it maximizes the payoff of all participating clients.
Exascale and Beyond: Configuring, Reasoning, Scaling. Report of the 2011 Workshop on Architectures II: Exascale and Beyond, held August 8-10, Albuquerque, N.M. (2011)

The push toward exascale computing (1) and beyond is torn between contradictory and possibly incompatible goals. On the one hand, one wants a system that will be available within a short span of time, on a relatively small development budget, and with the least changes possible to the current software stack. On the other hand, one wants a system that is orders of magnitude more efficient in its energy consumption. An exascale system could be as different from current systems as scalable parallel systems were from vector machines at the time of the last major transition in the field, but the amount of application software developed at DOE in the last decades makes it undesirable to take a “clean sheet of paper” approach, if at all possible. Furthermore, one wishes to explore and develop distinct exascale architectures to reduce risk while maintaining some unity so that application codes easily port among them. Finally, the design of an exascale system may involve a large number of vendors, some of which have limited experience in the field of High-Performance Computing (HPC). A proper integration of these multiple contributions requires a proper definition of many new interfaces, as well as consistent design principles for the handling of cross-cutting issues such as resilience, performance, and power management.
Preliminary report on the North Atlantic deep‐sea cores taken by the Geophysical Laboratory, Carnegie Institution (1937)

A series, of 11 cores from the North Atlantic sea‐bottom between the Newfoundland Banks and the banks off the Irish Coast have been studied by a group of geologists of the United States Geological Survey. These cores were taken by Dr. C. S. Piggot of the Carnegie Institution's Geophysical Laboratory from the cable ship Lord Kelvin with the explosive type of sounding‐apparatus, which he designed (C. S. Piggot, Apparatus to secure core‐samples from the oceanbottom, Bull. Geol. Soc. Amer., v. 47, pp. 675–684, 1936). This preliminary report is based largely on the results obtained by M. N. Bramlette, who studied the lithology, and Jos. A. Cushman, who studied the forarainifera. The geographic position, the depth of water at each station, and the length of core obtained are given in Table 1.
Impaired mesenteric leukocyte recruitment in experimental portal hypertension in the rat (1999)

Increased incidence of septic complications in human and experimental portal hypertension has been documented. Because development of an inflammatory response is essential in defense against infectious agents, the aim of this study was to assess leukocyte-endothelial cell interactions in an experimental model of portal hypertension. Intravital microscopy studies showed that under baseline conditions, leukocyte rolling, adhesion, and emigration in mesenteric venules were similar in control, sham operated (SO), and partial portal vein ligated (PPVL) rats. Compared with either control or SO rats, PPVL animals exhibited a markedly reduced recruitment of rolling, adherent, and emigrated leukocytes in response to leukotriene B(4) (LTB(4)) stimulation. Similarly, platelet-activating factor (PAF) superfusion, which induced a large increment in leukocyte rolling and adherence in control and SO rats, was without any effect in PPVL animals. Endothelial P-selectin expression in control rats, as measured by the double radio-labeled monoclonal antibody (mAb) technique, was not modified by LTB(4), but significantly increased in response to PAF. PPVL rats had a significantly lower expression of P-selectin after stimulation with PAF. Neutrophils isolated from PPVL rats exhibited increased L-selectin shedding and CD11b up-regulation in response to PAF and LTB(4), compared with neutrophils isolated from SO rats. These observations indicate that portal hypertension is associated with a defective inflammatory response, which is manifested as a decreased recruitment of rolling leukocytes, and subsequently reduced adhesion/emigration. This defect appears to result from a reduced endothelial P-selectin up-regulation and increased L-selectin shedding.
An overview of blockchain technologies: Principles, opportunities and challenges (2018)

Blockchain is a recently emerging technology that has the potential to revolutionize the way society interacts and trades between each other. The main advantage this technology provides is its ability to exchange transactions without relying on a trusted third party entities of any means. It can also provide data integrity, in-built authenticity and user transparency. Blockchain is envisioned to be the new internet on which many revolutionary applications will be based. In this work, we provide an overview of blockchain technologies including their principles, opportunities and challenges ahead.
Augmented Reality Meets Computer Vision : Efficient Data Generation for Urban Driving Scenes (2017)

The success of deep learning in computer vision is based on availability of large annotated datasets. To lower the need for hand labeled images, virtually rendered 3D worlds have recently gained popularity. Creating realistic 3D content is challenging on its own and requires significant human effort. In this work, we propose an alternative paradigm which combines real and synthetic data for learning semantic instance segmentation and object detection models. Exploiting the fact that not all aspects of the scene are equally important for this task, we propose to augment real-world imagery with virtual objects of the target category. Capturing real-world images at large scale is easy and cheap, and directly provides real background appearances without the need for creating complex 3D models of the environment. We present an efficient procedure to augment real images with virtual objects. This allows us to create realistic composite images which exhibit both realistic background appearance and a large number of complex object arrangements. In contrast to modeling complete 3D environments, our augmentation approach requires only a few user interactions in combination with 3D shapes of the target object. Through extensive experimentation, we conclude the right set of parameters to produce augmented data which can maximally enhance the performance of instance segmentation models. Further, we demonstrate the utility of our approach on training standard deep models for semantic instance segmentation and object detection of cars in outdoor driving scenes. We test the models trained on our augmented data on the KITTI 2015 dataset, which we have annotated with pixel-accurate ground truth, and on Cityscapes dataset. Our experiments demonstrate that models trained on augmented imagery generalize better than those trained on synthetic data or models trained on limited amount of annotated real data.
Ferroelectric Pb(Zr,Ti)O3 epitaxial layers on GaAs (2013)

Ferroelectric epitaxial Pb(Zr,Ti)O3 (PZT) layers were grown by pulsed laser deposition on SrTiO3/GaAs templates fabricated by molecular beam epitaxy. The templates present an excellent structural quality and the SrTiO3/GaAs is abrupt at the atomic scale. The PZT layers contain a- and c-domains, as shown by X-Ray diffraction analyses. Piezoforce microscopy experiments and macroscopic electrical characterizations indicate that PZT is ferroelectric. A relative dielectric permittivity of 164 is extracted from these measurements.