gebhart/patrepeval huggingface dataset:
PZT Based MFS Structure for FeFET (2003)

Fabrication and properties of lead zirconate titanate (PZT) thin films have been studied for Metal-Ferroelectric-Semiconductor FET (MFSFET) devices. PZT based MFS capacitors using lead titanate (PT) as seeding layers have been respectively prepared on p-type ⟨111⟩ and n-type ⟨100⟩ silicon wafers directly by a sol-gel method. PZT/PT films are final annealed at 650°C for 1 min in oxygen ambient using rapid thermal annealing (RTA). The measured memory windows of the MFS capacitors are about 1.8 V and 5 V under the polarization voltages of ±5 V and ±10 V correspondingly. The MFS structure can be valuable for MFSFET applications.
The ultrafiltration coefficient: this old 'grand inconnu' in dialysis (2013)

International audience
Development of an artificial diet for the western corn rootworm (2002)

Abstract The Western Corn Rootworm, Diabrotica virgifera (WCR; Coleoptera: Chrysomelidae), is a serious pest of maize, causing approximately one billion dollars a year in losses and control costs. The insect has become resistant to several chemical controls and growers have asked for a control solution based on genetically‐enhanced resistant varieties. Key to the production of genetically‐enhanced germ plasm is the ability to use artificial diets for bioassays to identify proteins with activity against the target insect. However, artificial diets currently used for WCR bioassay do not support good WCR larval development because they were developed and optimized for the Southern Corn Rootworm (SCR). The present study was conducted to understand the nutritional physiology of WCR by altering the dietary constituents of a SCR diet and measuring the subsequent effects on WCR growth. Alteration of most dietary constituents had surprisingly little effect on WCR larval growth. The most significant factors affecting WCR growth on artificial diet were removal of formalin, addition of plant adjuvant, and adjustment of dietary pH to 9.0. These dietary changes resulted in larval WCR growth rates that were nearly double those in standard SCR rootworm diets. In some cases, WCR larvae fed on the improved diet obtained larval masses approaching those of larvae fed on maize roots.
Crystallization and preliminary crystallographic analysis of 2-keto-3-deoxygluconate kinase fromThermus thermophilus (2004)

2-Keto-3-deoxygluconate kinase (KDGK) catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to 2-keto-3-deoxy-6-phosphogluconate. Two crystal forms of KDGK from Thermus thermophilus were obtained by vapour-diffusion and microbatch methods. Crystals in the form of triangular plates (TtKDGK-1) were obtained that belong to space group P3, with unit-cell parameters a = b = 145.83, c = 74.63 A, and diffract to 3.2 A. These crystals exhibited nearly perfect hemihedral twinning. Assigning six subunits of TtKDGK to the asymmetric unit of the crystal corresponds to a 46.2% solvent content. A single plate-like crystal (TtKDGK-2) belonged to space group P6(3), with unit-cell parameters a = b = 84.83, c = 168.49 A, and diffracts to 2.25 A. This crystal exhibits only partial hemihedral twinning, with a twin fraction of 24.4%. Diffraction-quality crystals of TtKDGK with bound ATP (TtKDGK-ATP), a = b = 84.72, c = 321.61 A and with bound KDG plus the ATP analogue AMP-PNP (TtKDGK-ATP-KDG), with unit-cell parameters a = b = 84.32, c = 168.7 A, were also prepared and characterized.
Telemonitor care helps CPAP compliance in patients with obstructive sleep apnea: a systemic review and meta-analysis of randomized controlled trials (2020)

TM care was associated with significantly greater CPAP compliance compared with usual care. Also, HAPT was not inferior to SPT for CPAP compliance.
Antimicrobial susceptibility in Mannheimia haemolytica isolated from high-risk Stocker cattle after metaphylaxis and treatment (2017)

Metaphylaxis (mass antimicrobial treatment) is commonly administered to high-risk cattle to limit bovine respiratory disease (BRD). While metaphylaxis decreases BRD morbidity and mortality, some cattle still require subsequent BRD treatments. Moreover, widespread application of anti-microbial drugs with extended duration of therapeutic concentrations in lung could increase antimicrobial resistance (AMR) in bacteria that cause BRD. Reports indicate increasing prevalence of AMR in Mannheimia haemolytica, the leading bacterial contributor to BRD in feedlot and Stocker cattle. The role that metaphylaxis has contributed to the recognized increase in AMR prevalence in M. haemolytica has not been well described. The impact of AMR on health outcomes in cattle managed to treat and control BRD is also not clear. The objective of this research was to describe the prevalence of AMR M. haemolytica in auction market-derived Stocker cattle that received a long acting macrolide for metaphylaxis, followed by treatment as necessary for BRD with other antimicrobials, over the first 21 days after receiving
Anti-Osteoactivin Antibody Inhibits Osteoblast Differentiation and Function In Vitro (2003)

Osteoactivin (OA) is a novel protein identified by mRNA differential display using bone from osteopetrotic versus normal rats. Bioinformatic analysis showed that OA cDNA has an open reading frame of 1716 bp encoding a protein of 572 aa, the first 21 aa constitute a signal peptide. OA sequence analysis also demonstrated 13 putative N-glycosylation sites suggestive of a heavily glycosylated protein. In this study, we localized OA protein in primary osteoblast culture by immunofluorescent staining and Western blot analysis. Primary osteoblast cultures pass through three stages: proliferation from day 1 to 7, matrix formation from day 7 to 14, and matrix mineralization from day 14 to 21. OA protein was detected at all stages examined, with maximal expression at 3 weeks when osteoblasts are terminally differentiated. Using the Chariot transfection reagent as a vehicle to deliver anti-OA antibody into the cells, we demonstrated that anti-OA antibody significantly inhibited osteoblast differentiation markers, including alkaline phosphatase activity, nodule formation, osteocalcin production, and calcium deposition, without affecting cell proliferation or viability. These data suggest that OA is an osteoblast-related protein that plays an important role in the regulation of osteoblast differentiation and function.
DNA cleavage activity of liblomycin (NK313), a novel analog of bleomycin. (1988)

Liblomycin (NK313), a novel analog of bleomycin and peplomycin (PEP), produced acid soluble DNA, base propenals and nucleo bases from isolated DNA. This was similar to the action of PEP. However, the DNA cleavage activity of NK313 was 1/2-1/10 of that of PEP in the absence of reducing agents. In the presence of reducing agents such as 2-mercaptoethanol and ascorbic acid, the activity of NK313 was stimulated more strongly than PEP. NK313 was also different from PEP in the formation and decomposition of active intermediates. This result suggested that differences in DNA cleavage activity between NK313 and PEP may be due to the different properties of their active intermediates. NK313 released preferentially pyrimidine bases from DNA, and the molar ratio of the released pyrimidine bases to the total of the released bases was little affected by the concentration of NK313 relative to DNA. In contrast, the ratio of the released purine bases by PEP increased with the concentration of PEP relative to DNA. NK313 induced double strand cleavage on pBR322 DNA as efficiently as did PEP. The major cleavage sites of NK313 on pBR322 DNA were similar to those of PEP. However, certain minor cleavage sites of NK313 were specific for NK313. Increase of PEP concentration led to increased degradation of DNA fragments; this was not the case with NK313. These results indicate that the cleavage sites of NK313 were similar to, but more limited than those for PEP.
False data injection attacks against state estimation in electric power grids (2009)

A power grid is a complex system connecting electric power generators to consumers through power transmission and distribution networks across a large geographical area. System monitoring is necessary to ensure the reliable operation of power grids, and state estimation is used in system monitoring to best estimate the power grid state through analysis of meter measurements and power system models. Various techniques have been developed to detect and identify bad measurements, including the interacting bad measurements introduced by arbitrary, non-random causes. At first glance, it seems that these techniques can also defeat malicious measurements injected by attackers.
Data from High-Density Single Nucleotide Polymorphism Array Defines Novel Stage and Location-Dependent Allelic Imbalances in Human Bladder Tumors (2023)

&lt;div&gt;Abstract&lt;p&gt;Bladder cancer is a common disease characterized by multiple recurrences and an invasive disease course in more than 10% of patients. It is of monoclonal or oligoclonal origin and genomic instability has been shown at certain loci. We used a 10,000 single nucleotide polymorphism (SNP) array with an average of 2,700 heterozygous SNPs to detect allelic imbalances (AI) in 37 microdissected bladder tumors from 17 patients. Eight tumors represented upstaging from Ta to T1, eight from T1 to T2+, and one from Ta to T2+. The AI was strongly stage-dependent as four chromosomal arms showed AI in &gt; 50% of Ta samples, eight in T1, and twenty-two in T2+ samples. The tumors showed stage-dependent clonality as 61.3% of AIs were reconfirmed in later T1 tumors and 84.4% in muscle-invasive tumors. Novel unstable chromosomal areas were identified at chromosomes 6q, 10p, 16q, 20p, 20q, and 22q. The tumors separated into two distinct groups, highly stable tumors (all Ta tumors) and unstable tumors (2/3 muscle-invasive). All 11 unstable tumors had lost chromosome 17p areas and 90% chromosome 8 areas affecting &lt;i&gt;Netrin-1/UNC5D/MAP2K4&lt;/i&gt; genes as well as others. AI was present at the &lt;i&gt;TP53&lt;/i&gt; locus in 10 out of 11 unstable tumors, whereas 6 had homozygous &lt;i&gt;TP53&lt;/i&gt; mutations. Tumor distribution pattern reflected AI as seven out of eight patients with additional upper urinary tract tumors had genomic stable bladder tumors (&lt;i&gt;P&lt;/i&gt; &lt; 0.05). These data show the power of high-resolution SNP arrays for defining clinically relevant AIs.&lt;/p&gt;&lt;/div&gt;
How to Ensure a Good Depth Perception on a Light Field Display (2021)

<italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">In this article, we define the technical requirements for a light field display to provide effective depth cues such as binocular disparity, motion parallax, and accommodation at a pixel resolution expected by the eye. These requirements are evaluated with respect to existing technologies (e.g.,integral imaging displays) or expected future ones (e.g., micro-light-emitting diode (LED) displays). Simulation of light field displays are proposed for different display sizes (smartphone, desktop, or TV), resolution per view, and pixel pitch. These simulations convey the main impact of the pixel pitch to reach the light field display goal in terms of depth cue requirements. The last part of the paper focusses on data generation issues: how to generate the necessary amount of views at the display side and what the adapted data formats are for such a purpose. The paper is associated with supplementary videos that will illustrate the view generation topic using a dedicated data format that is optimized for current graphics processing unit (GPU) processors. Video capture of early-stage light field displays will also be provided</i> .
Band-folding-driven high tunnel magnetoresistance ratios in (111)-oriented junctions with SrTiO$_3$ barriers (2022)

We theoretically study the tunnel magnetoresistance (TMR) effect in (111)-oriented magnetic tunnel junctions (MTJs) with SrTiO$_{3}$ barriers, Co/SrTiO$_{3}$/Co(111) and Ni/SrTiO$_{3}$/Ni(111). Our analysis combining the first-principles calculation and the Landauer formula shows that the Co-based MTJ has a high TMR ratio over 500%, while the Ni-based MTJ has a smaller value (290%). Since the in-plane lattice periodicity of SrTiO$_{3}$ is about twice that of the primitive cell of fcc Co (Ni), the original bands of Co (Ni) are folded in the $k_x$-$k_y$ plane corresponding to the $ab$ plane of the MTJ supercell. We find that this band folding gives a half-metallic band structure in the $Λ_1$ state of Co (Ni) and the coherent tunneling of such a half-metallic $Λ_1$ state yields a high TMR ratio. We also reveal that the difference in the TMR ratio between the Co- and Ni-based MTJs can be understood by different $s$-orbital weights in the $Λ_1$ band at the Fermi level.
Radiological Spectrum of Hepatic Mesenchymal Hamartoma in Children (2007)

A hepatic mesenchymal hamartoma in children can show a wide spectrum of radiological features, from a multiseptated cystic tumor to a mixed solid and cystic tumor, and even a solid tumor.
Loss of HDAC3 results in nonreceptive endometrium and female infertility (2019)

Endometriosis is a disease in which tissue that normally grows inside the uterus grows outside the uterus and causes chronic pelvic pain and infertility. However, the exact mechanisms of the pathogenesis of endometriosis-associated infertility are unknown. Epigenetic dysregulation has recently been implicated in infertility. Here, we report a reduction of histone deacetylase 3 (HDAC3) protein amounts in eutopic endometrium of infertile women with endometriosis compared to a control group. To investigate the effect of HDAC3 loss in the uterus, we generated mice with conditional ablation of <i>Hdac3</i> in progesterone receptor (PGR)-positive cells (<i>Pgr<sup>cre/+</sup>Hdac3<sup>f/f</sup></i> ; <i>Hdac3<sup>d/d</sup></i> ). Loss of <i>Hdac3</i> in the uterus of mice results in infertility due to implantation failure and decidualization defect. Expression microarray and ChIP-seq analyses identified <i>COL1A1</i> and <i>COL1A2</i> as direct targets of HDAC3 in both mice and humans. Reduction of <i>HDAC3</i> abrogated decidualization in a primary culture of human endometrial stromal cells (hESCs) similar to that observed in infertile patients with endometriosis. Whereas attenuation of <i>HDAC3</i> resulted in p300 recruitment to <i>Col1a1</i> and <i>Col1a2</i> genes in the uterus of mice as well as hESCs, inhibition of p300 permitted hESCs to undergo decidualization. Collectively, we found attenuation of HDAC3 and overexpression of collagen type I in the eutopic endometrium of infertile patients with endometriosis. HDAC3 loss caused a defect of decidualization through the aberrant transcriptional activation of <i>Col1a1</i> and <i>Col1a2</i> genes in mice and <i>COL1A1</i> and <i>COL1A2</i> genes in humans. Our results suggest that HDAC3 is critical for endometrial receptivity and decidualization.
Role of the Round Window Membrane in Middle Ear Immune Responses (1988)

(1988). Role of the Round Window Membrane in Middle Ear Immune Responses. Acta Oto-Laryngologica: Vol. 105, No. sup457, pp. 139-143.
Sup-picosecond, transform limited pulse generation in fiber CPA systems utilizing spectral pulse shaping with adaptive feedback loop (2012)

Fiber chirped pulse amplification (CPA) systems have many advantages such as size compactness and significant simplification of complex optical components over bulk solid state amplifiers. Moreover, precise optical alignment in free space is not required. However, fiber CPA systems are also much more vulnerable to nonlinear effects due to their small mode areas and long interaction length, resulting in pulse distortion, and consequently, degradation of pulse quality. Pulse with parabolic intensity profile appears to be a very good candidate to mitigate such degradation effects and wave-breaking. Furthermore, its linear chirp allows efficient pulse compression to achieve high peak power, making it highly attractive to CPA systems. CPA systems with parabolic pulses therefore can have widespread use in applications such as super-continuum generation, optic fiber communications, thermal ablation, and ultrafast all-optical signal processing.
Halogen-bond driven self-assembly of perfluorocarbon monolayers on silicon nitride (2019)

We demonstrate that self-assembled monolayers of reproducible thickness can be formed on silicon nitride, driven by halogen bonding using iodo-perfluorinated molecules.
An Optimization-Based Method for Feature Ranking in Nonlinear Regression Problems (2016)

In this paper, we consider the feature ranking problem, where, given a set of training instances, the task is to associate a score with the features in order to assess their relevance. Feature ranking is a very important tool for decision support systems, and may be used as an auxiliary step of feature selection to reduce the high dimensionality of real-world data. We focus on regression problems by assuming that the process underlying the generated data can be approximated by a continuous function (for instance, a feedforward neural network). We formally state the notion of relevance of a feature by introducing a minimum zero-norm inversion problem of a neural network, which is a nonsmooth, constrained optimization problem. We employ a concave approximation of the zero-norm function, and we define a smooth, global optimization problem to be solved in order to assess the relevance of the features. We present the new feature ranking method based on the solution of instances of the global optimization problem depending on the available training data. Computational experiments on both artificial and real data sets are performed, and point out that the proposed feature ranking method is a valid alternative to existing methods in terms of effectiveness. The obtained results also show that the method is costly in terms of CPU time, and this may be a limitation in the solution of large-dimensional problems.
A decompression core for PowerPC (1998)

Code size efficiency is a critical parameter in the design of computer systems for embedded applications. This paper describes a method for improving code size efficiency involving the use of compression techniques to reduce the size of the stored code, and on-the-fly hardware decompression at full processor speed for execution. A simple frequency-based encoding scheme for PowerPC® code achieves a typical code size reduction to 60% of the original size. A corresponding decompression core has been implemented for an embedded microprocessor, such as the PowerPC 401™. The compression/decompression scheme operates in a manner transparent to the processor and requires no changes to such tools as compilers, linkers, and loaders.
Low-Cost Amorphous Silicon Module Design for Long-Term Reliability (2008)

Low-cost amorphous silicon modules have the ability to generate significant economic value, provided that they can operate reliably throughout their intended service life. EPV Solar has developed their low-cost module design using an approach of 1) identifying failure modes found in outdoor testing, 2) developing tests to simulate these failures, and 3) using these tests to optimize the module design to improve long term reliability. As part of this process, EPV Solar has identified four key loss mechanisms that must be considered in a robust a-Si module design, including light-induced degradation, moisture ingress and corrosion, TCO delamination, and glass breakage. Approaches to mitigate these factors are discussed and accelerated tests are described to facilitate the module design process. Outdoor test results at the Florida Solar Energy Center have demonstrated that modules using the low-cost EPV Solar design are capable of an energy yield of over 1260 kWh/kWp/yr.
Lack of allelic exclusion permits autoreactive B cells to escape deletion. (1994)

The R4A-gamma 2b transgenic mouse harbors the gene for the gamma 2b heavy chain of an anti-dsDNA Ab. Approximately 80% of B cells expressing the transgene display allelic exclusion. Although the transgenic mice have little to no detectable serum anti-DNA activity, splenic B cells can be stimulated in vitro with LPS to secrete anti-DNA Ab. Hybridomas derived from LPS-stimulated splenic B cells were analyzed for expression of the transgene and for DNA binding. All nine transgene-encoded anti-DNA-producing lines were found to express an endogenous IgM heavy chain. Of 19 randomly selected lines producing a transgene-encoded non-DNA binding Ab, none expressed a second heavy chain. The tight correlation between lack of allelic exclusion and anti-dsDNA specificity provides strong support for the hypothesis that a major function of allelic exclusion is to prevent the maintenance of a pool of potentially activatable autoreactive cells.
Silanizing Glassware (1994)

This unit presents a procedure to silanize (siliconize) glassware to prevent adsorption of solute to the glass surface or to increase its hydrophobicity. This is particularly important when dealing with low concentrations of particularly "sticky" solutes such as single-stranded nucleic acids or proteins.
Thresholds Optimization for One-Bit Feedback Multi-User Scheduling (2018)

We propose a new one-bit feedback scheme with scheduling decision based on the maximum expected weighted rate. We show the concavity of the 2-user case and provide the optimal solution which achieves the maximum weighted rate of the users. For the general asymmetric M-user case, we provide a heuristic method to achieve the maximum expected weighted rate. We show that the sum rate of our proposed scheme is very close to the sum rate of the full channel state information case, which is the upper bound performance.
Budesonide Multimatrix Is Efficacious for Mesalamine-refractory, Mild to Moderate Ulcerative Colitis: A Randomised, Placebo-controlled Trial (2017)

Budesonide multimatrix was safe and efficacious for inducing clinical and endoscopic remission for mild to moderate ulcerative colitis refractory to oral mesalamine therapy.
Carbon Monoxide Poisoning: Pathogenesis, Management, and Future Directions of Therapy (2016)

Carbon monoxide (CO) poisoning affects 50,000 people a year in the United States. The clinical presentation runs a spectrum, ranging from headache and dizziness to coma and death, with a mortality rate ranging from 1 to 3%. A significant number of patients who survive CO poisoning suffer from long-term neurological and affective sequelae. The neurologic deficits do not necessarily correlate with blood CO levels but likely result from the pleiotropic effects of CO on cellular mitochondrial respiration, cellular energy utilization, inflammation, and free radical generation, especially in the brain and heart. Long-term neurocognitive deficits occur in 15-40% of patients, whereas approximately one-third of moderate to severely poisoned patients exhibit cardiac dysfunction, including arrhythmia, left ventricular systolic dysfunction, and myocardial infarction. Imaging studies reveal cerebral white matter hyperintensities, with delayed posthypoxic leukoencephalopathy or diffuse brain atrophy. Management of these patients requires the identification of accompanying drug ingestions, especially in the setting of intentional poisoning, fire-related toxic gas exposures, and inhalational injuries. Conventional therapy is limited to normobaric and hyperbaric oxygen, with no available antidotal therapy. Although hyperbaric oxygen significantly reduces the permanent neurological and affective effects of CO poisoning, a portion of survivors still have substantial morbidity. There has been some early success in therapies targeting the downstream inflammatory and oxidative effects of CO poisoning. New methods to directly target the toxic effect of CO, such as CO scavenging agents, are currently under development.