gebhart/patrepeval huggingface dataset:
Pilot Designs and Compensation Scheme for Severe RF Distortions in Millimeter-Wave Massive MIMO Systems (2016)

Emerging millimeter-wave massive MIMO systems are subject to strong radio frequency (RF) distortions and their compensation is crucial to meet the high performance targets of such systems. This paper presents novel pilot designs and related estimators for multi-input multi-output (MIMO) millimeter-wave systems characterized by frequency-selective channels, mirror interference, and time-varying inter-carrier interferences at both the transmitter and receiver. The bit error rate (BER) simulation results illustrate that our proposed designs achieve substantially lower BER than reference pilot designs in the literature.
An MRI guided system for prostate laser ablation with treatment planning and multi-planar temperature monitoring (2016)

Prostate cancer is often over treated with standard treatment options which impact the patients’ quality of life. Laser ablation has emerged as a new approach to treat prostate cancer while sparing the healthy tissue around the tumor. Since laser ablation has a small treatment zone with high temperature, it is necessary to use accurate image guidance and treatment planning to enable full ablation of the tumor. Intraoperative temperature monitoring is also desirable to protect critical structures from being damaged in laser ablation. In response to these problems, we developed a navigation platform and integrated it with a clinical MRI scanner and a side firing laser ablation device. The system allows imaging, image guidance, treatment planning and temperature monitoring to be carried out on the same platform. Temperature sensing phantoms were developed to demonstrate the concept of iterative treatment planning and intraoperative temperature monitoring. Retrospective patient studies were also conducted to show the clinical feasibility of the system.
Molecular Spherical Nucleic Acids* (2020)

Herein, we report a class of molecular spherical nucleic acid (SNA) nanostructures. These nano-sized single molecules are synthesized from T8 polyoctahedral silsesquioxane and buckminsterfullerene C60 scaffolds, modified with 8 and 12 pendant DNA strands, respectively. 1670These conjugates have different DNA surface densities and thus exhibit different levels of nuclease resistance, cellular uptake, and gene regulation capabilities; the properties displayed by the C60 SNA conjugate are closer to those of conventional and prototypical gold nanoparticle SNAs. Importantly, the C60 SNA can serve as a single entity (no transfection agent required) antisense agent to efficiently regulate gene expression. The realization of molecularly pure forms of SNAs will open the door for studying the interactions of such structures with ligands and living cells with a much greater degree of control than the conventional polydisperse forms of SNAs.
Chemical and Biological Aspects of Garcinol and Isogarcinol: Recent Developments (2019)

The natural polyisoprenylated benzophenone derivatives garcinol and isogarcinol are secondary plant metabolites isolated from various Garcinia species including Garcinia indica. This review takes stock of the recent chemical and biological research into these interesting natural compounds over the last five years. New biological sources and chemical syntheses are discussed followed by new insights into the activity of garcinol and isogarcinol against cancer, pathogenic bacteria, parasite infections and various inflammatory diseases.
Efficient Immobilization of a Cadmium Chemosensor in a Thin Film:  Generation of a Cadmium Sensor Prototype (2005)

[reaction: see text] The development of an ion-selective chemosensor for Cd(2+) allows generation of a "real-time" sensor. Immobilization of the chemosensor on quartz was achieved in a simple monolayer and in a thin film using a polymer intermediary. As intended, the thin film contains much more chemosensor than the monolayer and provides measurable responses to aqueous Cd(2+) concentrations below 1 microM. Alkali and alkaline earth ions do not interfere with Cd(2+) sensing; Zn(2+) and Cu(2+) are potential interferents.
Improvements in Testing Pole Slipping Protection Relays (ANSI 78) (2018)

This paper researches on the difficulty of adapting the protection parameters from different pole slipping protection (ANSI 78) relays to the state of the art test units with the task of improving the performance of the commissioning jobs and make sure for the protection engineer that the protection relay has been tested successfully and is ready for operation.
Enhancing Efficiency of Steam-Thermal Treatment of Formations With High-Viscosity Oil (2010)

Abstract The studies of the combined method of CHOPS and Cycling Steam Stimulation (CSS) of high viscosity oil reservoirs are described. Technological efficiency of the said stimulation compared with the traditional CSS shown and the main factors that influence the said process determined. The methods aimed at simulating the non-isothermal multi-phase fluid flow in a formation with wormholes within dual porosity/dual permeability model with parameters expressed as a coordinate function equivalent to the average parameters of the fractal structure described.
Proceedings of the 1st IMechE Automobile Division Southern Centre Conference on total vehicle technology : challenging current thinking, 18-19th September 2001, University of Sussex, Brighton, UK (2001)

Part 1 Safety systems: x-by-wire technology, D.A. Sanders and A. Baldwin strategies and technologies for advanced airbag regulations, S. Anishetty and D.R. Little the influence of Euro-NCAP on frontal impact safety, D. Haywood and M. Stonefrost. Part 2 Transport and energy: issues in the development of fuel cell systems for vehicles, R.K. Stobart the saturated liquid reservoir for energy storage in hybrid vehicles, F.J. Bayley low CO2 per kW engine concept, M.L.S. Flint digital road maps for intelligent transport systems, H. Bendafi and F. McCullough. Part 3 Analysis and calculation: more analysis, less vehicle testing - the management of risk, H. Jordan automated analysis and design modification of an engine mounting bracket, M. Pinfold et al development of a defrost system using CFD analysis, N.I.A. Haidar a numerical and experimental investigation into improving vehicle windshield defrosting and demisting, A. Aroussi et al. Part 4 Simulation and testing: the re-engineering of specifications expressed in terms of Finite State Machines through simulation and testing techniques, C. Giordano et al vibration simulation and comfort assessment as part of the vehicle design and development process, J. Venor order and digital order tracking using a synthesized phase reference signal to improve the quality of the tracks, A.J. Bennetts design validation, test correlation and added value testing methods, R.D. Atkins advances in the measurement of vehicle body stiffness, N.D. Rosam and S.J. Brooks visual noise investigation of a four-piston, opposed-type caliper, J.D. Fieldhouse and C.A. Beveridge analysis of data derived from a real disc brake system generating noise, C. Talbot and J.D. Fieldhouse. Part 5 Modelling: CAE optimization tools for developing vehicle ride comfort, D. Treneer et al optimization of a sports prototype race car for the Le Mans 24-hour race, R. Dominy probability distributions for modelling in-cylinder air velocities in a G-DI internal combustion engine, S. Savic et al new approaches to analytical and numerical modelling of fuel sprays, S.S. Sazhin et al physical versus neural network models of automotive dampers, A. Patel and J.F. Dunne. Part 6 Production: the use of distributed intelligence within advanced production machinery for design applications, G.E. Tewkesbury and D.A. Sanders an automatic system for simple spot welding tasks, D.A. Sanders and Z. Rasol. Part 7 Design: the styling process, C. Milburn and P.R.N. Childs.
Cross-Domain 3D Model Retrieval Based On Contrastive Learning And Label Propagation (2022)

In this work, we aim to tackle the task of unsupervised image based 3D model retrieval, where we seek to retrieve unlabeled 3D models that are most visually similar to the 2D query image. Due to the challenging modality gap between 2D images and 3D models, existing mainstream methods adopt domain-adversarial techniques to eliminate the gap, which cannot guarantee category-level alignment that is important for retrieval performance. Recent methods align the class centers of 2D images and 3D models to pay attention to the category-level alignment. However, there still exist two main issues: 1) the category-level alignment is too rough, and 2) the category prediction of unlabeled 3D models is not accurate. To overcome the first problem, we utilize contrastive learning for fine-grained category-level alignment across domains, which pulls both prototypes and samples with the same semantic information closer and pushes those with different semantic information apart. To provide reliable semantic prediction for contrastive learning and also address the second issue, we propose the consistent decision for pseudo labels of 3D models based on both the trained image classifier and label propagation. Experiments are carried out on MI3DOR and MI3DOR-2 datasets, and the results demonstrate the effectiveness of our proposed method.
Development of robot hand that grasps various items placed in various situations (2021)

Due to the labor shortage, there is a strong need for automation of material handling and picking operations in logistics and manufacturing sites. Developed robot hand can grasps various items placed in various places, including small space. This makes it possible to automate the handling of various items in logistics and manufacturing sites. The robot hand is the size of a human arm and can switch between suction and pinching according to the situation of the item to be grasped. The robot hand has an independent controller and can be expected to be used in various industrial robot arms. In this paper, the advantages of the developed robot hand and the results of its application to a picking robot are presented.
Investigational drug therapies for the treatment of gastroparesis (2017)

Gastroparesis is defined by nausea, vomiting, pain, early satiety and bloating, and characterized by delayed gastric emptying without obvious structural abnormalities. Metoclopramide is widely used, increasing gastric emptying and inhibiting nausea and vomiting. Other drugs are available in certain countries and some are used 'off-label' because they increase gastric emptying or inhibit emesis. However, correlation between gastroparesis symptoms and rates of gastric emptying is poor. For anti-emetic drugs, dose-ranging and Phase III trials in gastroparesis are lacking. Areas covered: Gastric motility may still be disordered, leading to nausea, even though gastric emptying is unchanged. One hypothesis is that interstitial cells of Cajal (ICC) are damaged by diabetes leading to gastric dysrhythmia and nausea. Novel approaches to treatment of nausea also include the use of ghrelin receptor agonists, highlighting a link between appetite and nausea. Expert opinion: There is an urgent need to diversify away from historical drug targets. In particular, there is a need to control nausea by regulating ICC functions and/or by facilitating appetite via ghrelin receptor agonists. It is also important to note that different upper gastrointestinal disorders (gastroparesis, chronic unexplained nausea and vomiting, functional dyspepsia) are difficult to distinguish apart, suggesting wider therapeutic opportunity.
Fabrication of ferroelectric SrBi2Ta2O9 capacitor films using plasma-assisted metalorganic chemical vapor deposition and their electrical properties (2001)

The fabrication of SrBi2Ta2O9 (SBT) films using plasma-assisted metalorganic chemical vapor deposition (P-MOCVD) has been investigated. Optimizing the process conditions under plasma environment, amorphous SBT films were successfully deposited at a substrate temperature below 300 °C, suggesting that the P-MOCVD process effectively utilizes plasma energy to promote the reaction and decomposition of metal organic source molecules. The amorphous SBT films were crystallized to the bilayered perovskite SBT films by a postannealing at 725 °C. Thin SBT capacitors fabricated using P-MOCVD showed a good step coverage and the excellent ferroelectric properties including endurance. Low voltage operation below 1.5 V was successfully achieved using a 75 nm SBT capacitor, in which the signal level derived from the hysteresis curve suggests the feasibility of application to a 64 Mbit ferroelectric random access memories.
How does adding and removing liquid from socket bladders affect residual-limb fluid volume? (2013)

Adding and removing liquid from socket bladders is a means for people with limb loss to accommodate residual-limb volume change. We fit 19 people with transtibial amputation using their regular prosthetic socket with fluid bladders on the inside socket surface to undergo cycles of bladder liquid addition and removal. In each cycle, subjects sat, stood, and walked for 90 s with bladder liquid added, and then sat, stood, and walked for 90 s again with the bladder liquid removed. The amount of bladder liquid added was increased in each cycle. We used bioimpedance analysis to measure residual-limb fluid volume. Results showed that the preferred bladder liquid volume was 16.8 +/- 8.4 mL (mean +/- standard deviation), corresponding with 1.7% +/- 0.8% of the average socket volume between the bioimpedance voltage-sensing electrodes. Residual-limb fluid volume driven out of the residual limb when bladder liquid was added was typically not recovered upon subsequent bladder liquid removal. Of the 19 subjects, 15 experienced a gradual residual-limb fluid volume loss over the test session. Care should be taken when implementing adjustable socket technologies in people with limb loss. Reducing socket volume may accentuate residual-limb fluid volume loss.
Detection of Genomic Lesions in Childhood Precursor-B Cell ALL in Diagnosis and Relapse Samples Using High Resolution Genomic Profiling. (2007)

Abstract Due to advances in therapeutic regimens developed during the last two decades, the majority of children with acute lymphoblastic leukemia (ALL) respond well to therapy. However, in approximately 25% of the patients relapses occur. Chomosome aneuploidies and recurrent chromosomal translocations are of considerable prognostic importance, and are routinely used in the course of clinical decision making. Current technological developments in molecular cytogenetic techniques have revealed that genetic lesions driving tumorigenesis frequently occur at the submicroscopic level and, consequently, escape standard cytogenetic observations. Therefore, we have previously performed high resolution genomic profiling of precursor-B-cell ALL samples obtained at diagnosis, using 250k NspI SNP-based oligoarrays from Affymetrix (Kuiper et al., 2007). By doing so, we detected multiple de novo genetic lesions, some of which were subtle and affected single genes. Many of these lesions involved recurrent (partially) overlapping deletions and duplications, encompassing various established leukemia-associated genes, such as ETV6, RUNX1, and MLL. Importantly, the most frequently affected genes were those controlling G1/S cell cycle progression (e.g. CDKN2A, CDKN1B, and RB1), followed by genes associated with B-cell development. The latter group included the B-lineage transcription factors PAX5, EBF, E2-2, and IKZF1 (Ikaros), as well as genes with other established roles in B-cell development, i.e., RAG1 and RAG2, FYN, PBEF1, or CBP/PAG. Here we have selected 34 additional precursor-B cell ALL cases that suffered from relapses 6 months to 9 years after diagnosis. Lesions affecting genes involved in G1/S cell cycle progression and B-cell development were observed with similar frequencies in the diagnosis and relapse samples as compared to our previous cohort of patients with unknown therapy response. However, additional (secondary) lesions were observed in the relapse samples in nearly all patients analyzed, indicating that these relapse samples are genomically distinct. In addition, several cases were encountered in which the diagnosis and relapse samples carried alternative lesions affecting the same gene(s), including CDKN2A and PAX5, suggesting that inactivation of these genes were secondary but essential events required to develop a full blown leukemia.
Supplementary Video from Molecular imaging of Bcr-Abl phosphokinase in a xenograft model (2023)

Supplementary Video from Molecular imaging of Bcr-Abl phosphokinase in a xenograft model
Local Strain Evaluation of Strained-SOI Structures (2005)

The strain relaxation within a strained-Si on SiGe on insulator (SGOI) structure might be one of the key issues in development of strained-Si MOSFET devices for high-performance ULSIs. In order to investigate the strain relaxation within the thin strained-Si layers, a new characterization technique to directly evaluate a local strain variation in the layers is required. Hence, we have developed the nano-beam electron diffraction (NBD) method which has a lateral resolution of 10 nm and a strain resolution of 0.1%. In this paper, we discuss a detailed investigation of whether the NBD method could be utilized to clarify a strain in a strained-Si layer on the SGOI structures.
A Log-Structured Persistent Store (1996)

Persistent stores have been implemented using a variety of storage technologies including shadow paging, log-based and log-structured approaches. Here we compare these approaches and advocate the use of log-structuring. The advantages of such a technique include efficient support for large (64 bit) address spaces, scalability and fast snapshot processing. We describe the architecture of a new log-structured persistent store and how it has been used to support resilient persistent processes in the context of the Grasshopper operating system. This store is based on the use of a log server which provides clients with private logical logs. Keywords persistent stores, log-structured stores, recoverable virtual memory. 1 Introduction The concept of persistence may be defined as the attribute of data which specifies its period of existence. Stemming from this simple definition, a wide range of systems supporting various forms of persistence have emerged. In systems that support orthogonal ...
Transport parameters for an ultrasonic pulsed wave propagating in a multiple scattering medium (1999)

We have developed a set of experimental methods using ultrasonic transducers arrays to characterise a multiple scattering medium. A sample made of a large number of randomly located steel rods has been used as a prototype. We were able to estimate the elastic mean free path, the absorption mean free path, the transport mean free path and the diffusion constant.
ChemInform Abstract: Rhodium Dinaphthocyclooctatetraene Complexes: Synthesis, Characterization and Catalytic Activity in [5 + 2] Cycloadditions. (2012)

Abstract The synthesis of dinaphthylcyclooctatetraenes and novel cationic Rh‐complexes derived therefrom is described.
Generalized Memory Polynomial Model Dimension Selection Using Particle Swarm Optimization (2018)

This letter presents a new method which uses particle swarm optimization and the Akaike information criterion for determining the dimensions of nonlinear amplifier behavioral models, applied to the generalized memory polynomial model. Determining the size of this model has always been a challenge as it depends on eight parameters, and the proposed method provides a fast and efficient solution which can discover the smallest possible model at a very short amount of time.
Long‐Term Outcomes after Pocket or Scar Revision and Reimplantation of Pacemakers with Preerosion (2010)

The reimplantation of pulse generators with preerosion in the presence of local inflammatory manifestations or granulomatous-like changes of the scar is complicated by documented cardiac pacemaker infection in >50% of cases. In these patients, the explantation of the pacing system is recommended before the development of prognostically much more serious spread of infection to the leads and cardiac tissues.
Deoxyhexanucleotide containing a vinyl chloride induced DNA lesion, 1,N6-ethenoadenine: synthesis, physical characterization, and incorporation into a duplex bacteriophage M13 genome as part of an amber codon (1987)

Organic synthesis and recombinant DNA techniques have been used to situate a single 1,N6-ethenoadenine (epsilon Ade) DNA adduct at an amber codon in the genome of an M13mp19 phage derivative. The deoxyhexanucleotide d[GCT(epsilon A)GC] was chemically synthesized by the phosphotriester method. Mild nonaqueous conditions were employed for deprotection because of the unstable nature of the epsilon Ade adduct in aqueous basic milieu. Physical studies involving fluorescence, circular dichroism, and 1H NMR indicated epsilon Ade to be very efficiently stacked in the hexamer, especially with the 5'-thymine. Melting profile and circular dichroism studies provided evidence of the loss of base-pairing capabilities attendant with formation of the etheno ring. The modified hexanucleotide was incorporated into a six-base gap formed in the genome of an M13mp19 insertion mutant; the latter was constructed by blunt-end ligation of d(GCTAGC) in the center of the unique SmaI site of M13mp19. Phage of the insertion mutant, M13mp19-NheI, produced light blue plaques on SupE strains because of the introduced amber codon. Formation of a hybrid between the single-strand DNA (plus strand) of M13mp19-NheI with SmaI-linearized M13mp19 replicative form produced a heteroduplex with a six-base gap in the minus strand. The modified hexamer [5'-32P]d-[GCT(epsilon A)GC], after 5'-phosphorylation, was ligated into this gap by using bacteriophage T4 DNA ligase to generate a singly adducted genome with epsilon Ade at minus strand position 6274. Introduction of the radiolabel provided a useful marker for characterization of the singly adducted genome, and indeed the label appeared in the anticipated fragments when digested by several restriction endonucleases. Evidence that ligation occurred on both 5' and 3' sides of the oligonucleotide also was obtained. The adduct was introduced into a unique NheI site, and it was observed that this restriction endonuclease was able to cleave the adducted genome, albeit at a lower rate compared to unmodified DNA. The M13mp19-NheI genome containing epsilon Ade will be used as a probe for studying mutagenesis and repair of this DNA adduct in Escherichia coli.
Revisiting Normalized Gradient Descent: Fast Evasion of Saddle Points (2017)

The note considers normalized gradient descent (NGD), a natural modification of classical gradient descent (GD) in optimization problems. A serious shortcoming of GD in non-convex problems is that GD may take arbitrarily long to escape from the neighborhood of a saddle point. This issue can make the convergence of GD arbitrarily slow, particularly in high-dimensional non-convex problems where the relative number of saddle points is often large. The paper focuses on continuous-time descent. It is shown that, contrary to standard GD, NGD escapes saddle points `quickly.' In particular, it is shown that (i) NGD `almost never' converges to saddle points and (ii) the time required for NGD to escape from a ball of radius $r$ about a saddle point $x^*$ is at most $5\sqrtκr$, where $κ$ is the condition number of the Hessian of $f$ at $x^*$. As an application of this result, a global convergence-time bound is established for NGD under mild assumptions.