gebhart/patrepeval huggingface dataset:
Photocycloaddition of dimethyl acetylenedicarboxylate and methyl propiolate to benzo[b]furans (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotocycloaddition of dimethyl acetylenedicarboxylate and methyl propiolate to benzo[b]furansAlois H. A. Tinnemans and Douglas C. NeckersCite this: J. Org. Chem. 1977, 42, 14, 2374–2377Publication Date (Print):July 1, 1977Publication History Published online1 May 2002Published inissue 1 July 1977https://pubs.acs.org/doi/10.1021/jo00434a006https://doi.org/10.1021/jo00434a006research-articleACS PublicationsRequest reuse permissionsArticle Views110Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Novel design of UHF RFID near-field antenna for smart shelf applications (2013)

This paper presents the design of UHF RFID read/write (R/W) antenna to be used in a variety of smart shelf retail applications. The design principle based on the EM coupling between open-ended MS feed line and periodic planar metal strips is presented. The proposed antenna can be easily customized for the required aria of smart shelf RFID interrogation. Several antenna prototypes have been designed, produced and measured. The antenna performance has been evaluated in UHF RFID system for the simultaneous detection of arbitrary oriented tagged apparel items placed on the antenna surface. The proposed antenna demonstrates excellent ability to provide strong and uniform E-field distribution at the distances up to 50 cm form the antenna surface.
Laser Beam Welding of a Low Density Refractory High Entropy Alloy (2019)

The effect of laser beam welding on the structure and properties of a Ti1.89NbCrV0.56 refractory high entropy alloy was studied. In particular, the effect of different pre-heating temperatures was examined. Due to the low ductility of the material, laser beam welding at room temperature resulted in the formations of hot cracks. Sound butt joints without cracks were produced using pre-heating to T ≥ 600 °C. In the initial as-cast condition, the alloy consisted of coarse bcc grains with a small amount of lens-shaped C15 Laves phase particles. A columnar microstructure was formed in the welds; the thickness of the grains increased with the temperature of pre-heating before welding. The Laves phase particles were formed in the seams after welding at 600 °C or 800 °C, however, these particles were not observed after welding at room temperature or at 400 °C. Soaking at elevated temperatures did not change the microstructure of the base material considerably, however, “additional” small Laves particles formed at 600 °C or 800 °C. Tensile test of welded specimens performed at 750 °C resulted in the fracture of the base material because of the higher hardness of the welds. The latter can be associated with the bcc grains refinement in the seams.
Cellular electrophysiological principles that modulate secretion from synovial fibroblasts (2016)

Rheumatoid arthritis (RA) is a progressive disease that affects both pediatric and adult populations. The cellular basis for RA has been investigated extensively using animal models, human tissues and isolated cells in culture. However, many aspects of its aetiology and molecular mechanisms remain unknown. Some of the electrophysiological principles that regulate secretion of essential lubricants (hyaluronan and lubricin) and cytokines from synovial fibroblasts have been identified. Data sets describing the main types of ion channels that are expressed in human synovial fibroblast preparations have begun to provide important new insights into the interplay among: (i) ion fluxes, (ii) Ca<sup>2+</sup> release from the endoplasmic reticulum, (iii) intercellular coupling, and (iv) both transient and longer duration changes in synovial fibroblast membrane potential. A combination of this information, knowledge of similar patterns of responses in cells that regulate the immune system, and the availability of adult human synovial fibroblasts are likely to provide new pathophysiological insights.
Baidu Neural Machine Translation Systems for WMT19 (2019)

In this paper we introduce the systems Baidu submitted for the WMT19 shared task on ChineseEnglish news translation. Our systems are based on the Transformer architecture with some effective improvements. Data selection, back translation, data augmentation, knowledge distillation, domain adaptation, model ensemble and re-ranking are employed and proven effective in our experiments. Our ChineseEnglish system achieved the highest case-sensitive BLEU score among all constrained submissions, and our EnglishChinese system ranked the second in all submissions.
Wavelength demultiplexing heterojunction phototransistor (1990)

Experimental and theoretical results on a wavelength demultiplexing receiver composed of an AlGaAs/GaAs heterojunction phototransistor (HPT) integrated within a resonant cavity are reported. A high quality factor cavity was formed using a very thin In0.05Ga0.95As active absorption layer in the collector depletion region of the HPT. Crosstalk attenuations of 15dB for dual and 12dB for triple wavelength demultiplexing were demonstrated. The individual HPTs had an optical gain of 500 at the resonant modes. Theoretical calculations predict crosstalk attenuation levels as high as 40 dB with high reflection mirrors on both ends of the cavity.
Synthesis of novel prepolymers containing no bisphenol A and preparation of organic matrices for dental applications (2006)

Two kinds of novel bifunctional methacrylated prepolymers (170-2MA and 631-2MA) which have similar structure with 2,2-bis[4- (2'-hynroxy-3'-methacryloyloxypropoxy)phenyl] propane (Bis-GMA) was synthesized for dental applications as an alternative to Bis-GMA containing bisphenol A that is doubtful as an endocrine disrupter. The organic matrices were prepared by mixing a diluent and/or a monomer with the synthesized methacrylated prepolymers. The yield, viscosity, and chemical structures of the prepolymers and the physical and methanical properties of the organic matrices were evaluated. The yields of the prepolymers synthesized through a ring-opening reaction of epoxy compound and methacrylic acid were above 90% and the viscosities of the prepolymers were much lower than that of the Bis-GMA control. From the results of and FTIR analyses, the chemical structures of the prepolymers were similar to that of Bis-GMA. In addition, the curing time, poly-merization shrinkage, photoconversion, polymerization depth, and compressive strength of the organic matrices formulated with 170-2MA and 631-2MA prepolymers exhibited comparable to or better than those of the existing Bis-GMA-based one. These results suggest that the novel methacrylated prepolymers which have no endocrine disrupter can be an alternative to Bis-GMA and be applicable to dental polymer materials.
Determination of Carbonyl Compounds in Exhaled Cigarette Smoke (2007)

Abstract This paper presents the findings on a quantitative evaluation of carbonyl levels in exhaled cigarette smoke from human subjects. The cigarettes evaluated include products with 5.0 mg ‘tar’, 10.6 mg ‘tar’ and 16.2 mg ‘tar’, where ‘tar’ is defined as the weight of total wet particulate matter (TPM) minus the weight of nicotine and water, and the cigarettes are smoked following U.S. Federal Trade Commission (FTC) recommendations. The measured levels of carbonyls in the exhaled smoke were compared with calculated yields of carbonyls in the inhaled smoke and a retention efficiency was obtained. The number of human subjects included a total of ten smokers for the 10.6 mg ‘tar’, five for the 16.2 mg ‘tar’, and five for the 5.0 mg ‘tar’ product, each subject smoking three cigarettes. The analyzed carbonyl compounds included several aldehydes (formaldehyde, acetaldehyde, acrolein, propionaldehyde, crotonaldehyde and n-butyraldehyde), and two ketones (acetone and 2-butanone). The smoke collection from the human subjects was vacuum assisted. Exhaled smoke was collected on Cambridge pads pretreated with a solution of dinitrophenylhydrazine (DNPH) followed by high performance liquid chromatography (HPLC) analysis of the dinitrophenylhydrazones of the carbonyl compounds. The cigarette butts from the smokers were collected and analyzed for nicotine. The nicotine levels for the cigarette butts from the smokers were used to calculate the level of carbonyls in the inhaled smoke, based on calibration curves. These were generated separately by analyzing the carbonyls in smoke and the nicotine in the cigarette butts obtained by machine smoking under different puffing regimes. The comparison of the level of carbonyl compounds in exhaled smoke with that from the inhaled smoke showed high retention of all the carbonyls. The retention of aldehydes was above 95% for all three different ‘tar’ levels cigarettes. The ketones were retained with a slightly lower efficiency. Acetone was retained in the range of 90% to 95%. The retention for 2-butanone showed a larger scatter compared to other results but it also appeared to be slightly less absorbed than the aldehydes, with an average retention around 95%. The retention of acetaldehyde and acetone by human smokers was previously reported in literature and the findings from this study are in very good agreement with these result.
Quasicrystals at extreme conditions: The role of pressure in stabilizing icosahedral Al63Cu24Fe13at high temperature (2015)

Icosahedrite, the first natural quasicrystal with composition Al<sub>63</sub>Cu<sub>24</sub>Fe<sub>13</sub>, was discovered in several grains of the Khatyrka meteorite, a unique CV3 carbonaceous chondrite. The presence in the meteorite fragments of icosahedrite strictly associated with high-pressure phases like ahrensite and stishovite indicates a formation conditions at high pressures and temperatures, likely during an impact-induced shock occurred in contact with the reducing solar nebula gas. In contrast, previous experimental studies on the stability of synthetic icosahedral AlCuFe, which were limited to ambient pressure, indicated incongruent melting at ~1123 K, while high-pressure experiments carried out at room temperature showed structural stability up to about 35 GPa. These data are insufficient to experimentally constrain the formation and stability of icosahedrite under extreme conditions. Here we present the results of in situ high pressure experiments using diamond anvil cells of the compressional behavior of synthetic icosahedrite up to ~50 GPa at room temperature. Simultaneous high P-T experiments have been also carried out using both laser-heated diamond anvil cells combined with in situ synchrotron X-ray diffraction (at ~42 GPa) and multi-anvil apparatus (at 21 GPa) to investigate the structural evolution of icosahedral Al<sub>63</sub>Cu<sub>24</sub>Fe<sub>13</sub> and crystallization of possible coexisting phases. The results demonstrate that the quasiperiodic symmetry of icosahedrite is retained over the entire experimental pressure range explored. In addition, we show that pressure acts to stabilize the icosahedral symmetry at temperatures much higher than previously reported. Based on our experimental study, direct crystallization of Al-Cu-Fe quasicrystals from an unusual Al-Cu-rich melt would be possible but limited to a narrow temperature range beyond which crystalline phases would form, like those observed in the Khatyrka meteorite. Here, an alternative mechanism would consist in late formation of the quasicrystal after crystallization and solid-solid reaction of Al-rich phases. In both cases, linking our results with observations in nature, quasicrystals are expected to preserve their structure even after hypervelocity impacts that involve simultaneous high pressures and temperatures, thus proving their cosmic stability.
Dissociation of the effects of amylin on osteoblast proliferation and bone resorption (1998)

This study assesses the structure-activity relationships of the actions of amylin on bone. In fetal rat osteoblasts, only intact amylin and amylin-(1-8) stimulated cell proliferation (half-maximal concentrations 2.0 x 10(-11) and 2.4 x 10(-10) M, respectively). Amylin-(8-37), COOH terminally deamidated amylin, reduced amylin, and reduced amylin-(1-8) (reduction results in cleavage of the disulfide bond) were without agonist effect but acted as antagonists to the effects of both amylin and amylin-(1-8). Calcitonin gene-related peptide-(8-37) also antagonized the effects of amylin and amylin-(1-8) on osteoblasts but was substantially less potent in this regard than amylin-(8-37). In contrast, inhibition of bone resorption in neonatal mouse calvariae only occurred with the intact amylin molecule and was not antagonized by any of these peptides. The rate of catabolism of the peptides in calvarial cultures was not accelerated in comparison with that of intact amylin. This dissociation of the actions of amylin suggests that it acts through two separate receptors, one on the osteoclast (possibly the calcitonin receptor) and a second on the osteoblast.
Wideband force sensing for haptic energy transmission utilizing FPGA (2008)

Haptic and/or tactile information has been paid attention as the third multimedia information. An electric motor with the disturbance observer is a good candidate to achieve haptic ability because it is possible to match actuation and sensation. Furthermore, it is possible to convert haptic energy into electric energy. The paper discusses necessity for the framework of haptic energy transmission. Especially, the paper proposes both theory and implementation method. To enlarge the bandwidth of a disturbance observer, the paper proposes super wideband force sensing using a field-programmable gate array (FPGA). Since an FPGA is implemented in it, the control performance is superior to human’s sensation. The experimental results show viability of the proposed method.
Structure of nogalamycin bound to a DNA hexamer. (1990)

The anthracycline antibiotic nogalamycin, which binds to DNA, is composed of a planar aglycone substituted on each end to form an unusual dumbbell-shaped molecule. At one end nogalamycin contains an uncharged nogalose sugar and a methyl ester. At the other end nogalamycin contains a positively charged bicyclo amino sugar. We report the crystal structure of nogalamycin bound to the self-complementary DNA hexamer d(m5CGTsAm5CG). In this complex, the cytosines are methylated at the 5 position and the DNA contains a phosphorothioate linkage at the TpA step. Two nogalamycin molecules bind to the 6-base-pair fragment of double-helical DNA. The drug has threaded between the phosphodiester backbones with three aromatic rings intercalated within the DNA. In the major groove, the bicyclo amino sugar forms two direct hydrogen bonds to span a CG base pair and interacts indirectly with the next base pair of the duplex via a water-mediated hydrogen bond. In the minor groove, a carbonyl oxygen of nogalamycin forms a hydrogen bond directly to N2 of a guanine. The DNA base pairs are severely buckled by up to 26 degrees and are also distorted in directions perpendicular to the Watson-Crick hydrogen bonds. This complex illustrates the deformable nature of DNA.
A high-dynamic range (HDR) back-side illuminated (BSI) CMOS image sensor for extreme UV detection (2012)

This paper describes a back-side illuminated 1 Megapixel CMOS image sensor made in 0.18um CMOS process for EUV detection. The sensor applied a so-call "dual-transfer" scheme to achieve low noise, high dynamic range. The EUV sensitivity is achieved with backside illumination use SOI-based solution. The epitaxial silicon layer is thinned down to less than 3um. The sensor is tested and characterized at 5nm to 30nm illumination. At 17.4nm targeted wavelength, the detector external QE (exclude quantum yield factor) reaches almost 60%. The detector reaches read noise of 1.2 ph- (@17.4nm), i.e. close to performance of EUV photon counting.
Highly efficient UV-based conversion LEDs for the generation of saturated colors with improved eye safety (2004)

Recently near UV conversion LEDs with an excitation wavelength of around 400nm have attracted increasing interest due to their high efficiency and output power. Favorably is also the great variety of efficient phosphors available for near UV excitation. For the generation of saturated colors this method is very efficient especially for dominant wavelengths from 480 nm to 570 nm. Direct light emission from InGaN chips show a strong temperature and current dependency increasing with the emission wavelength and may cause disturbing color shifts in applications. For the wavelength range between 530 nm to 570 nm the physical limitations of the InGaN system are reached and the efficiency of the InGaAlP system is not yet satisfying. Conversion LED's based on near UV-light emitting chips provide solutions for both problems. But up to now a disadvantage of these LEDs is the residual near UV-light emission which could lead to severe eye damages over time. OSRAM OS developed a eye safe solution by avoiding the near UV-peak while maintaining the high luminous efficiency. A luminous efficiency of 28 lm/W for &#955;<sub>dom</sub> of approx. 560 nm was demonstrated, a value more than ten times higher than the efficiency of green emitting InGaAlP diodes. For these LEDs no more restrictions because of eye safety regulations are expected.
Supplemental figure 2 from Tumor-Infiltrating Lymphocytes Genetically Engineered with an Inducible Gene Encoding Interleukin-12 for the Immunotherapy of Metastatic Melanoma (2023)

&lt;p&gt;Supplemental figure 2. Phenotype of NFAT.IL12 gene modified TIL compared to matched untransduced TIL.Shown are the percentage of cells with a phenotype consistent with effector memory (CD62L-CD45RA-),central memory (CD62L+CD45RA-), Naive (CD62+, CD45RA+) and EMRA (CD62L-CD45RA+).UT, untransduced.&lt;/p&gt;
Natural and recombinant A and B gene encoded glycosyltransferases (2001)

The human blood group A and B synthesizing enzymes are glycosyltransferases that catalyse the transfer of a monosaccharide residue from UDP-GalNAc and UDP-Gal donors, respectively, to alphaFuc1,2-Gal terminated blood group H acceptors. Extensive investigations of their substrate specificity and physical properties have been carried out since their initial discovery. These studies demonstrated a rigid specificity for the acceptor structure, crossover in donor specificity and immunological similarity along with chromatographic differences. Cloning of the enzymes has shown that they are highly homologous, differing in only four of their 354 amino acids. Changing the residues Arg176-->Gly, Gly235-->Ser, Leu266-->Met and Gly 268-->Ala converts the enzyme specificity from blood group A to blood group B glycosyltransferase. Structure function investigations have been carried out by systematic interchange and modification of these four critical amino acids. These studies have shown that donor specificity is attributed to the last two amino acids. Mutants have also been produced with greatly enhanced turnover rates as well as hybrid A/B enzymes that catalyse both reactions efficiently.
Ross and Yasui operations for complex biventricular repair in infants with critical left ventricular outflow tract obstruction☆ (2009)

Case selection is key for complex biventricular repair and the importance of appropriate case selection is exaggerated at young ages. All available options should be considered before pursuing the Ross operation in the presence of co-existing functional morphological abnormalities or emergent iatrogenic aortic regurgitation. However, both the Ross and Yasui operations in children (including neonates and young infants) with favourable functional morphology offer good survival, at least matching that of other biventricular repair strategies.
STUDIES OF ADHESION OF METAL PARTICLES TO SILICA PARTICLES BASED ON ZETA POTENTIAL MEASUREMENTS (1999)

Abstract The zeta-potentials of silica, copper, platinum and gold particles have been measured as a function of pH. The isoelectric points were found to be at pH 3.0, 5.8, 3.0 and 3.5, respectively. In the pH range 3.0 to 5.8 copper and silica particles are oppositely charged and accordingly the coating of silica with copper particles could be demonstrated. In the case of gold and platinum the sign of the charge is such that direct adhesion to silica particles cannot be expected and this was also demonstrated in the case of platinum.
Paramagnetic lanthanide chelates for multicontrast MRI (2016)

The preparation of a paramagnetic chelator that serves as a platform for multicontrast MRI, and can be utilized either as a T1-weighted, paraCEST or (19)F MRI contrast agent is reported. Its europium(iii) complex exhibits an extremely slow water exchange rate which is optimal for the use in CEST MRI. The potential of this platform was demonstrated through a series of MRI studies on tube phantoms and animals.
[Molecular biology of depressive disorders]. (2007)

Heritability of major depression from twin studies is estimated as -40% that is relatively small as compared with -80% for schizophrenia and -90% for bipolar affective disorder. It suggests that genetic as well as environmental factors contribute to the aetiology of major depression. Approximately 800 association studies on candidate genes of depression have been published, and among them, several genes were confirmed as risk for vulnerability to major depression by meta-analyses. Recent investigations on pathophysiology of depression have focused on hippocampus as a modulator of Hypothalamus-Pituitary-Adrenal (HPA) glands axis. Molecular biological studies on the interaction between stress, hippocampus and HPA axis reveal glucocorticoid and brain-derived neurotrophic factor(BDNF) are key molecules developing and recovering from depressive disorder.
1  kW, 200  mJ picosecond thin-disk laser system (2017)

We report on a laser system based on thin-disk technology and chirped pulse amplification, providing output pulse energies of 200 mJ at a 5 kHz repetition rate. The amplifier contains a ring-type cavity and two thin Yb:YAG disks, each pumped by diode laser systems providing up to 3.5 kW power at a 969 nm wavelength. The average output power of more than 1 kW is delivered in an excellent output beam characterized by M<sup>2</sup>=1.1. The output pulses are compressed to 1.1 ps at full power with a pair of dielectric gratings.
ChemInform Abstract: 3‐Pyridyloxypropanolamide Agonists (I) of the β3 Adrenergic Receptor with Improved Pharmacokinetic Properties (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.