PD43-05 EXTERNAL VALIDATION OF A PRIAPISM QUESTIONNAIRE IN A JAMAICAN COHORT OF SICKLE CELL DISEASE PATIENTS (2019)

You have accessJournal of UrologySexual Function/Dysfunction: Evaluation II (PD43)1 Apr 2019PD43-05 EXTERNAL VALIDATION OF A PRIAPISM QUESTIONNAIRE IN A JAMAICAN COHORT OF SICKLE CELL DISEASE PATIENTS Ayodeji Sotimehin*, Bruce Trock, Uzoma Anele, Wendy Madden, Belinda Morrison, and Arthur Burnett Ayodeji Sotimehin*Ayodeji Sotimehin* More articles by this author , Bruce TrockBruce Trock More articles by this author , Uzoma AneleUzoma Anele More articles by this author , Wendy MaddenWendy Madden More articles by this author , Belinda MorrisonBelinda Morrison More articles by this author , and Arthur BurnettArthur Burnett More articles by this author View All Author Informationhttps://doi.org/10.1097/01.JU.0000556573.08014.75AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVES: Little is known about the long-term consequences of recurrent priapism on erectile function, penile deformity, and mental health. The Priapism Impact Profile (PIP) is a 12-item instrument used to measure three key domains presumed to be worsened by priapism: quality-of-life (QoL), sexual function (SF), and physical wellness (PW) and has been previously validated in adults with priapism. In this study, we evaluated the validity and reliability of PIP in a Jamaican cohort of sickle cell disease (SCD) patients experiencing priapism. METHODS: 100 SCD patients with a history of priapism were recruited from a sickle cell clinic in Kingston, Jamaica and administered the PIP questionnaire. Patients then rated each item of the PIP for clarity and importance. 20 of the 100 patients repeated the PIP questionnaire within 1 year of initial testing. Statistical testing was employed to evaluate the validity and reliability of PIP. RESULTS: Patients were divided into active priapism (54) and remission (46) groups based on whether they experienced a priapism episode within the past year. Patients in the active priapism group were older (p < 0.05), had a shorter duration of disease (p <0.05), and had more frequent priapism episodes (p<0.05) than the remission group. The active priapism group had higher total PIP score and worse QoL, SF, and PW scores than the remission group (p<0.05 for all). The item-total Cronbach's α reliability coefficient for the PIP score was 0.78. Individual PIP domains had α coefficients of 0.77 for QoL, 0.78 for SF, and 0.81 for PW. These values are consistent with a good (r > 0.70) item domain/total instrument interrelatedness. Questions were rated as having medium or high clarity and importance by an average of 82% and 69% of patients, respectively. CONCLUSIONS: The PIP questionnaire was successfully validated in a cohort of SCD patients and adequately discriminated patients with active priapism from those in remission. Source of Funding: None Baltimore, MD; Richmond, VA; Kingston, Jamaica; Baltimore, MD© 2019 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 201Issue Supplement 4April 2019Page: e757-e757 Advertisement Copyright & Permissions© 2019 by American Urological Association Education and Research, Inc.MetricsAuthor Information Ayodeji Sotimehin* More articles by this author Bruce Trock More articles by this author Uzoma Anele More articles by this author Wendy Madden More articles by this author Belinda Morrison More articles by this author Arthur Burnett More articles by this author Expand All Advertisement PDF downloadLoading ...