gebhart/patrepeval huggingface dataset:
Organic Electronics: Spatial Mapping of Morphology and Electronic Properties of Air‐Printed Pentacene Thin Films (Adv. Funct. Mater. 25/2014) (2014)

M. Shtein and co-workers use guard flow-enhanced organic vapor jet printing for the additive patterning of pentacene thin fifilms in air, and perform in situ X-ray diffraction to relate process variables, oxidation, structural defects, and electronic properties in thin-film transistor applications. The process structureproperty relationship is quantifified, and the field-effect mobility is extrapolated based on the processing conditions. The schematic shown represents the GF-OVJP process with in situ diffraction and contacts for TFT measurements.
IoT fault management platform with device virtualization (2018)

The Internet of Things (IoT) has been growing. In a Field Area Network (FAN), where various IoT devices with different protocols and data formats are connected, faults can easily occur due to the FAN's instability. In this paper, a novel platform is proposed to provide a fault management function to the complicated FAN. The platform hides the differences between the devices by virtualizing them and provides fault analysis methods flexibly according to the FAN components with a plug-in structure.
Pulsation-Amplitude-Dependent Flame Dynamics of High-Frequency Thermoacoustic Oscillations in Lean-Premixed Gas Turbine Combustors (2017)

This paper presents the experimental investigation of pulsation-amplitude-dependent flame dynamics associated with transverse thermoacoustic oscillations at screech level frequencies in a generic gas turbine combustor. Specifically, the flame behavior at different levels of pulsation amplitudes is assessed and interpreted. Spatial dynamics of the flame are measured by imaging the OH⋆ chemiluminescence (CL) signal synchronously to the dynamic pressure at the combustor's face plate. First, linear thermoacoustic stability states, modal dynamics, and flame-acoustic phase relations are evaluated. It is found that the unstable acoustic modes converge into a predominantly rotating character in the direction of the mean flow swirl. Furthermore, the flame modulation is observed to be in phase with the acoustic pressure at all levels of the oscillation amplitude. Second, distributed flame dynamics are investigated by means of visualizing the mean and oscillating heat release distribution at different pulsation amplitudes. The observed flame dynamics are then compared against numerical evaluations of the respective amplitude-dependent thermoacoustic growth rates, which are computed using analytical models in the fashion of a noncompact flame-describing function. While results show a nonlinear contribution for the individual growth rates, the superposition of flame deformation and displacement balances out to a constant flame driving. This latter observation contradicts the state-of-the-art perception of root-causes for limit-cycle oscillations in thermoacoustic gas turbine systems, for which the heat release saturates with increasing amplitudes. Consequently, the systematic observations and analysis of amplitude-dependent flame modulation shows alternative paths to the explanation of mechanisms that might cause thermoacoustic saturation in high frequency systems.
Editorial (2016)

Balakirsky (Georgia Tech Research institute) and Murad Kurwa (Flex)
Cryoablation and Meriva have strong therapeutic effect on triple-negative breast cancer (2015)

Interleukin-6, a cytokine produced particularly by triple-negative breast cancers, strongly inhibits T cell responses in the tumor microenvironment. Here we tested cryoablation combined with Meriva (a lecithin delivery system of curcumin with improved bioavailability) in mice with metastatic breast cancer (4T1). Cryoablation involves killing of tumor cells through freezing and thawing, resulting in recruitment of tumor-specific T cells, while curcumin stimulates T cells through the reduction of IL-6 in the TME. Cryoablation plus Meriva accumulated and activated CD8<sup>+</sup> T cells to multiple tumor-associated antigens such as Mage-b and Survivin (both expressed by 4T1 tumors). This correlated with a nearly complete reduction of 4T1 primary tumors and lung metastases while little effect was observed from saline or Meriva alone (28 d after tumor cell injection). The survival rate in the group of cryoablation plus Meriva was significantly improved compared to all control groups. Using a less aggressive 4T1 model expressing luciferase (4T1.2luc3), we demonstrated that all mice receiving saline or Meriva developed metastases in the lungs and a primary tumor (38 d after tumor cell injection; and died soon after that), but not the mice receiving cryoablation or cryoablation plus Meriva. However, on day 58 the mice receiving cryoablation developed 4T1.2luc3 metastases in the lungs, while mice receiving cryoablation plus Meriva were free of metastases. These results strongly suggest that cryoablation delayed the development of lung metastases on the short-term, but Meriva administered after cryoablation was significantly better in delaying the development of lung metastases and survival on the long-term.
Step-specific Sorting of Mouse Spermatids by Flow Cytometry (2015)

The differentiation of mouse spermatids is one critical process for the production of a functional male gamete with an intact genome to be transmitted to the next generation. So far, molecular studies of this morphological transition have been hampered by the lack of a method allowing adequate separation of these important steps of spermatid differentiation for subsequent analyses. Earlier attempts at proper gating of these cells using flow cytometry may have been difficult because of a peculiar increase in DNA fluorescence in spermatids undergoing chromatin remodeling. Based on this observation, we provide details of a simple flow cytometry scheme, allowing reproducible purification of four populations of mouse spermatids fixed with ethanol, each representing a different state in the nuclear remodeling process. Population enrichment is confirmed using step-specific markers and morphological criterions. The purified spermatids can be used for genomic and proteomic analyses.
High Fundamental Mode Power, High Speed InAlGaAs/AlGaAs 1310 and 1550-nm Wafer-Fused VCSELs (2008)

InAlGaAs/AlGaAs-based wafer-fused long-wavelength VCSELs with tunnel junction injection emitting in the 1310 nm and 1550 nm bands show high single-mode output and high speed modulation capabilities of 10 Gbps. Fundamental emission close to 6 mW at room temperature and 2.5 mW at 80oC for both 1310 nm and 1550 nm devices is demonstrated for the first time.
<title>Embeddable distributed moisture and pH sensors for nondestructive inspection of aircraft lap joints</title> (1995)

Two distributed fiber optic sensors for use in the prevention and monitoring of corrosion in aircraft are described. These sensors, based on optical fibers that are intrinsically sensitive to either water or changes in pH, will alert maintenance personnel to the presence of water in lap joints and other inaccessible critical areas. Furthermore, the sensors can also locate precisely where the moisture infiltration has occurred. In a typical application, a sensor fiber would be embedded in a lap joint along the bottom panel of an aircraft's body, or on a wing, where water is likely to collect. Changes in the optical transmission through the fiber can be monitored either periodically or continuously to determine the extent of water penetration.
Down-regulation of Laminin-Binding Integrins by 1α,25=Dihydroxyvitamin D3in Human Melanoma Cells in Vitro (1998)

In the present investigation the effect of 1 alpha,25(OH)2D3 on the expression of the integrin laminin receptor on the melanoma cell line SK-MEL-28 has been examined. The SK-MEL-28 cells were shown to contain high-affinity receptors for 1 alpha,25(OH)2D3 and cell proliferation was found to be inhibited in a dose-dependent manner in response to the hormone. Using monoclonal antibodies against the alpha 6-sub-unit of the integrin laminin receptor, immunocytochemistry demonstrated that exposure of cells to 1 alpha,25(OH)2D3 for 5 days caused a reduced staining intensity. This observation was further confirmed by dot blot analysis, where a dose-dependent decline of alpha 6 expression was obtained after treatment of the cells with 1 alpha,25(OH)2D3 for 6 days. FACS-analysis was performed in order to quantify this decline, and it was found that the level of alpha 6-subunits on the cell surface was reduced by more than 40%. Additional investigations including Northern blot analyses of poly(A)+RNA extracts also showed a dose-dependent reduction of alpha 6 mRNA. Interestingly, the decrease of alpha 6 expression on the surface of SK-MEL-28 melanoma cells was accompanied by a reduced ability of the cells to adhere to an artificial basement membrane. In conclusion, the present investigation shows that besides having an antiproliferative effect on the SK-MEL-28 melanoma cells, 1 alpha,25(OH)2D3 is also able to inhibit the surface expression of the alpha 6-subunit of the integrin laminin receptor. Moreover, the results strongly indicate that 1 alpha,25(OH)2D3 exerts its regulatory effect on the alpha 6-subunit at the transcriptional level rather than at the protein level.
ChemInform Abstract: SYNTHESIS AND CONFORMATIONS OF α‐AMINOADIPYL‐ AND GLYCYL‐α‐AMINOADIPYLTHIAZEPINE SULFOXIDES (1981)

Abstract Umsetzung des Aminoacrylats (II) (Darstellung beschrieben) mit D‐Penicillamin (III) liefert das Thiazepin (IVa) und das 6‐D‐Epimere (IVb) [nachfolgende Veresterung zu (IVc) bzw. (IVd)].Das aus (IVa) erhältliche Hydrobromid (IVe) wird in den Ester (VI) übergeführt, der mit den (bekannten) Aminosäurederivaten (Ia) bzw. (Ib) zu den Verbindungen (VIIa) bzw. (VIIb) umgesetzt wird.
Supplementary Data from Predicting Clinical Outcome through Molecular Profiling in Stage III Melanoma (2023)

Supplementary Data from Predicting Clinical Outcome through Molecular Profiling in Stage III Melanoma
Defining the Pediatric Spinal Thoracoscopy Learning Curve (2000)

The learning curve for thoracoscopy is substantial, but not prohibitive. This technique provides a safe and effective alternative to thoracotomy in the treatment of pediatric spinal deformity.
The recirculating screw mixer: A new small‐volume mixer for the polymer laboratory (1993)

Abstract The recirculating screw mixer (RSM), a new small‐volume intensive mixer for the polymer laboratory, is designed, built, modeled, and tested. This type of batch mixer is intended for the mixing of 1 to 30 cm 3 of viscous material at high shear rates. A material element in the mixer experiences alternating screw pump and tubular flows with reorientation between these flows. A mixer with a 10 cm 3 sample capacity is built for testing and evaluation. Flow visualization experiments are used to investigate the quality of the distributive mixing achieved. The flows in the mixer are modeled for the cases of a Newtonian fluid and a power law fluid. The Newtonian model accurately predicts the recirculation time for particles suspended in Newtonian silicone oils. The power law model accurately predicts the screw torque obtained with a polystyrene and polyethylene. A method for the measurement of fluid rheology from the operating conditions of the RSM is proposed and tested. The mixing achieved by the RSM is compared to that obtained by a batch mixer with roller blades. Both mixers are used to prepare blends of ethylene‐propylene rubber in polystyrene. The morphologies of the resultant blends are compared and differences in the mixing action are discussed. The mixers are also used to prepare composites of fumed silica in polyethylene. The quality of mixing obtained in the RSM compares quite favorably with that obtained in the batch mixer with roller blades for polystyrene/ethylene‐propylene rubber reactive blends and polyethylene/silica composites.
One-day bonding effectiveness of new self-etch adhesives to bur-cut enamel and dentin. (2005)

Self-etch adhesives try to solve difficulties commonly associated with the clinical application of etch-and-rinse adhesives. Their application procedure is considered less time-consuming and, more importantly, less technique-sensitive. The main objective of this study was to determine the bonding effectiveness to and the interaction with enamel/dentin of three contemporary one- and two-step self-etch adhesives by microtensile bond strength testing (microTBS), Fe-SEM and TEM when compared to a control two-step self-etch and a three-step etch-and-rinse adhesive. The one-step self-etch adhesive, Adper Prompt (3M ESPE), scored the lowest microTBS of all experimental and control adhesives tested. Conversely, the two-step self-etch adhesives Clearfil SE (Kuraray) and OptiBond Solo Plus Self-Etch (Kerr) approached the values obtained by the three-step etch-and-rinse control (OptiBond FL, Kerr) when bonded to enamel and dentin. Ultramorphological characterization showed that interfacial morphology and the pH of the self-etch primer/adhesive are strongly associated. The interaction with dentin varied from the formation of a submicron, hydroxyapatite-containing hybrid layer for the "mild" self-etch adhesive Clearfil SE to a 3-5 microm thick, hydroxyapatite-depleted hybrid layer for the "strong" self-etch adhesive Adper Prompt. The two-step self-etch adhesives AdheSE and OptiBond Solo Plus Self-Etch presented with a hybrid layer with a hydroxyapatite-depleted top part and a hydroxyapatite-containing base part and were therefore classified into a new group of self-etch adhesives, namely "intermediary strong" self-etch adhesives.
COVID-19 global pandemic planning: Performance and electret charge of N95 respirators after recommended decontamination methods (2020)

Shortages of N95 respirators for use by medical personnel have driven consideration of novel conservation strategies, including decontamination for reuse and extended use. Decontamination methods listed as promising by the Centers for Disease Control and Prevention (CDC) (vaporous hydrogen peroxide (VHP), wet heat, ultraviolet irradiation (UVI)) and several methods considered for low resource environments (bleach, isopropyl alcohol and detergent/soap) were studied for two commonly used surgical N95 respirators (3M™ 1860 and 1870+ Aura™). Although N95 filtration performance depends on the electrostatically charged electret filtration layer, the impact of decontamination on this layer is largely unexplored. As such, respirator performance following decontamination was assessed based on the fit, filtration efficiency, and pressure drop, along with the relationship between (1) surface charge of the electret layer, and (2) elastic properties of the straps. Decontamination with VHP, wet heat, UVI, and bleach did not degrade fit and filtration performance or electret charge. Isopropyl alcohol and soap significantly degraded fit, filtration performance, and electret charge. Pressure drop across the respirators was unchanged. Modest degradation of N95 strap elasticity was observed in mechanical fatigue testing, a model for repeated donnings and doffings. CDC recommended decontamination methods including VHP, wet heat, and UV light did not degrade N95 respirator fit or filtration performance in these tests. Extended use of N95 respirators may degrade strap elasticity, but a loss of face seal integrity should be apparent during user seal checks. NIOSH recommends performing user seal checks after every donning to detect loss of appropriate fit. Decontamination methods which degrade electret charge such as alcohols or detergents should not be used on N95 respirators. The loss of N95 performance due to electret degradation would not be apparent to a respirator user or evident during a negative pressure user seal check.
Hostility in adolescents and adults: a genome-wide association study of the Young Finns (2011)

Hostility is a multidimensional personality trait with changing expression over the life course. We performed a genome-wide association study (GWAS) of the components of hostility in a population-based sample of Finnish men and women for whom a total of 2.5 million single-nucleotide polymorphisms (SNPs) were available through direct or in silico genotyping. Hostility dimensions (anger, cynicism and paranoia) were assessed at four time points over a 15-year interval (age range 15-30 years at phase 1 and 30-45 years at phase 4) in 982-1780 participants depending on the hostility measure. Few promising areas from chromosome 14 at 99 cM (top SNPs rs3783337, rs7158754, rs3783332, rs2181102, rs7159195, rs11160570, rs941898, P values <3.9 × 10(-8) with nearest gene Enah/Vasp-like (EVL)) were found suggestively to be related to paranoia and from chromosome 7 at 86 cM (top SNPs rs802047, rs802028, rs802030, rs802026, rs802036, rs802025, rs802024, rs802032, rs802049, rs802051, P values <6.9 × 10(-7) with nearest gene CROT (carnitine O-octanoyltransferase)) to cynicism, respectively. Some shared suggestive genetic influence for both paranoia and cynicism was also found from chromosome 17 at 2.8 cM (SNPs rs12936442, rs894664, rs6502671, rs7216028) and chromosome 22 at 43 cM (SNPs rs7510759, rs7510924, rs7290560), with nearest genes RAP1 GTPase activating protein 2 (RAP1GAP2) and KIAA1644, respectively. These suggestive associations did not replicate across all measurement times, which warrants further study on these SNPs in other populations.
4D Deep Learning for Multiple Sclerosis Lesion Activity Segmentation (2020)

Multiple sclerosis lesion activity segmentation is the task of detecting new and enlarging lesions that appeared between a baseline and a follow-up brain MRI scan. While deep learning methods for single-scan lesion segmentation are common, deep learning approaches for lesion activity have only been proposed recently. Here, a two-path architecture processes two 3D MRI volumes from two time points. In this work, we investigate whether extending this problem to full 4D deep learning using a history of MRI volumes and thus an extended baseline can improve performance. For this purpose, we design a recurrent multi-encoder-decoder architecture for processing 4D data. We find that adding more temporal information is beneficial and our proposed architecture outperforms previous approaches with a lesion-wise true positive rate of 0.84 at a lesion-wise false positive rate of 0.19.
Resonance Raman spectroelectrochemistry. IV. The oxygen decay chemistry of the tetracyanoquinodimethane dianion (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTResonance Raman spectroelectrochemistry. IV. The oxygen decay chemistry of the tetracyanoquinodimethane dianionMary R. Suchanski and Richard P. Van DuyneCite this: J. Am. Chem. Soc. 1976, 98, 1, 250–252Publication Date (Print):January 1, 1976Publication History Published online1 May 2002Published inissue 1 January 1976https://pubs.acs.org/doi/10.1021/ja00417a049https://doi.org/10.1021/ja00417a049research-articleACS PublicationsRequest reuse permissionsArticle Views487Altmetric-Citations109LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Supplementary Data Figure S2 from ARX788, a Site-specific Anti-HER2 Antibody–Drug Conjugate, Demonstrates Potent and Selective Activity in HER2-low and T-DM1–resistant Breast and Gastric Cancers (2023)

&lt;p&gt;ARX788 activity in HER2-transduced MDA-MB-435 pools. MDA-MB-435 cells transduced with HER2 were sorted into pools with low, medium, and high HER2 expression and quantified for HER2 expression by QiFiKit analysis. Parental MDA-MB-435 cells and the pools were treated with ARX788 for 3 days at 37{degree sign}C, and cell viability was measured.&lt;/p&gt;
A broad-host-range expression vector based on the pL promoter of coliphage lambda: regulated synthesis of human interleukin 2 in Erwinia and Serratia species (1987)

We report the construction of a broad-host-range expression vector based on an RSF1010-derived replicon. The vector carries the strong leftward promoter (pL) of coliphage lambda as well as the cI857 allele, which codes for a thermolabile repressor protein. The coding region of mature human interleukin 2, which is preceded by the ner ribosome binding site of phage Mu, was cloned downstream from the pL promoter. The plasmid was introduced into Erwinia and Serratia species by means of mobilization. Heat-inducible synthesis of interleukin 2 protein was obtained, showing that the pL promoter is functional in these genera. As in Escherichia coli, the bulk of the overproduced protein was present in an insoluble form.
Auditing for Distributed Storage Systems (2012)

Distributed storage codes have recently received a lot of attention in the community. Independently, another body of work has proposed integrity checking schemes for cloud storage, none of which, however, is customized for coding-based storage or can efficiently support repair. In this work, we bridge the gap between these two currently disconnected bodies of work. We propose NC-Audit, a novel cryptography-based remote data integrity checking scheme, designed specifically for network coding-based distributed storage systems. NC-Audit combines, for the first time, the following desired properties: (i) efficient checking of data integrity, (ii) efficient support for repairing failed nodes, and (iii) protection against information leakage when checking is performed by a third party. The key ingredient of the design of NC-Audit is a novel combination of SpaceMac, a homomorphic message authentication code (MAC) scheme for network coding, and NCrypt, a novel chosen-plaintext attack (CPA) secure encryption scheme that is compatible with SpaceMac. Our evaluation of a Java implementation of NC-Audit shows that an audit costs the storage node and the auditor a modest amount computation time and lower bandwidth than prior work.