gebhart/patrepeval huggingface dataset:
Utilizing Social Influence in Content Distribution Networks (2011)

Online social networks (OSNs) provide new means of disseminating information about applications and contents served by network providers. OSN members often reveal their usage information and opinion about applications and contents to their neighbors within their social networks. Consequently, sudden popularity and viral propagation of applications among OSN members can put significant burden on network resources and degrade network performance. Further, viral exchanges might propagate malicious applications and such propagation might need to be kept in check. Accordingly, we propose a novel content distribution architecture that controls the resource utilization within an operator's network by utilizing the existing social connections between users and building a model of information diffusion within the social network. Our method is based upon computing a reward function that takes into account the influence of users over each other in a given social network in terms of application adoption and content consumption. Based on this reward function and assuming that not only the users but also the network operator can limit the exposure of application usage and content consumption over the online social networks, we present algorithms to slow down or speed up the adoption/consumption of different applications/contents given the current state of both the physical network and the social network. We evaluate the effectiveness of this method over a Flickr data set. Results suggest that such a control is indeed possible and the proposed method significantly outperforms other approaches that employs mainly degree-based mechanisms for controlling the information dissemination over the social graphs.
ChemInform Abstract: Intramolecular Nickel Catalyzed Cycloadditions of Bisdienes: 3 Approaches to the Taxane Skeleton. (1987)

Abstract The key step in the synthesis of the cyclooctadiene derivatives (IV) and (VIII) is the Ni‐catalyzed intramolecular (4 + 4)cycloaddition of the tetraenes (III) and (VII).
Theoretical and experimental CD of conformationally flexible complex molecules?application to ouabain pentanaphthoate and analogs (1999)

Theoretical calculation of circular dichroic exciton-coupled spectra of ouabain 1,19,2',3',4'-pentanaphthoate and its analogs was executed by a combination of conformational analysis with molecular mechanics and quantum-chemical calculation. Most of the calculated CD spectra show good agreement with the corresponding experimental data, which suggests that the method may be generalized for applications to other conformationally flexible natural products. The CD calculation was then used to evaluate the plausibility of "fortuitous CD cancellation," which was observed in the microscale naphthoylation study of hypothalamic inhibitory factor, a presumed ouabain isomer from bovine hypothalamus.
Ear-EEG from generic earpieces: A feasibility study (2013)

The use of brain monitoring based on EEG, in natural environments and over long time periods, is hindered by the limited portability of current wearable systems, and the invasiveness of implanted systems. To that end, we introduce an ear-EEG recording device based on generic earpieces which meets key patient needs (discreet, unobstrusive, user-friendly, robust) and that is low-cost and suitable for off-the-shelf use; thus promising great advantages for healthcare applications. Its feasibility is validated in a comprehensive comparative study with our established prototype, based on a personalized earpiece, for a key EEG paradigm.
Using a whole-body 31P birdcage transmit coil and 16-element receive array for human cardiac metabolic imaging at 7T (2017)

This easy-to-assemble, volume-transmit, local receive array coil combination significantly improves the homogeneity and field-of-view for metabolic imaging of the human heart at 7T.
Supply Chain Sustainability Analysis of Renewable Hydrocarbon Fuels via Indirect Liquefaction, Hydrothermal Liquefaction, Combined Algal Processing, and Biochemical Conversion: Update of the 2021 State-of-Technology Cases (2022)

The Department of Energy’s (DOE) Bioenergy Technologies Office (BETO) aims to develop and deploy technologies to transform renewable biomass resources into commercially viable, high-performance biofuels, bioproducts, and biopower through public and private partnerships. BETO and its national laboratory teams conduct in-depth techno-economic assessments (TEA) of biomass feedstock supply and logistics and conversion technologies to produce biofuels. There are two general types of TEAs: A design case outlines a target case (future projection) for a particular biofuel pathway. It informs R&D priorities by identifying areas in need of improvement, tracks sustainability impact of R&D, and provides goals and benchmarks against which technology progress is assessed. A state of technology (SOT) analysis assesses progress within and across relevant technology areas based on actual results at current experimental scales relative to technical targets and cost goals from design cases, and includes technical, economic, and environmental criteria as available.
A Map of the Interactome Network of the Metazoan C. elegans (2004)

To initiate studies on how protein-protein interaction (or "interactome") networks relate to multicellular functions, we have mapped a large fraction of the Caenorhabditis elegans interactome network. Starting with a subset of metazoan-specific proteins, more than 4000 interactions were identified from high-throughput, yeast two-hybrid (HT=Y2H) screens. Independent coaffinity purification assays experimentally validated the overall quality of this Y2H data set. Together with already described Y2H interactions and interologs predicted in silico, the current version of the Worm Interactome (WI5) map contains approximately 5500 interactions. Topological and biological features of this interactome network, as well as its integration with phenome and transcriptome data sets, lead to numerous biological hypotheses.
Efficient evaluation of a 2-feed method to reduce fields along the edge of the power/ground planes (2006)

A 2-feed scheme is studied on reducing the noise in packaging due to edge fields in the rectangular Power/Ground planes. For efficient and accurate prediction of the fields’ behavior along the edges of the structure with respect to feeding conditions, a fast single sum is derived to consider loads. Solving example structures will show the differential signaling can improve the problems and be affected by loading.
PROPERTIES AND RECOVERY OF WASTE LIQUIDS FROM CITRUS PECTIN POMACE MANUFACTURE (1978)

ABSTRACT A complete flow diagram and material balance of a typical citrus pectin pomace manufacturing process is presented. Leach liquids, produced from lemon and lime peel during the process had the following waste treatment properties: COD, 10,000–12,000 ppm: BOD. 6,000–9,000 ppm, settleable matter, 50–250 ppm; turbidity, 215–1200 N.T.U. The presence of water‐soluble pectin (40–100 mg/100g) in the dilute leach liquids contributed to high viscosities and made concentration by evaporation difficult. Commercial leaching processes removed approximately 20% of the total solids in the peel, while a more efficient laboratory leaching was able to recover over 30% of the solids.
Simultaneous strain and tomographic imaging with coupled photorefractive holography and shearography through turbid media (2008)

peer reviewed
Procédures d'installation et monitoring (2022)

This document describes the practical setup and external usage of the IoT platform based on Long Range Wide Area Network (LoRaWAN) and deployed for the experiments of the Intelligentsia project.
Comparison of the Life-Span of NbC-Co and WC-Co Inserts During Different Machining Operations on 100Cr6 (SAE 52100) Bearing Steel (2015)

International audience
Applicability of YANG models for Abstraction and Control of Traffic Engineered Networks (1999)

Abstraction and Control of TE Networks (ACTN) refers to the set of
virtual network operations needed to orchestrate, control and manage
large-scale multi-domain TE networks, so as to facilitate network
programmability, automation, efficient resource sharing, and end-to-
end virtual service aware connectivity and network function
virtualization services. This document explains how the different
types of YANG models defined in the Operations and Management Area and
in the Routing Area are applicable to the ACTN framework. This
document also shows how the ACTN architecture can be satisfied using
classes of data model that have already been defined, and discusses
the applicability of specific data models that are under development.
It also highlights where new data models may need to be developed.
Dynamics of the angular emission spectrum of large-area VCSELs (2009)

High power VCSELs can be realized by scaling up the active area of bottom-emitting devices. This results in a large Fresnel number of the laser cavity. The laser beam cannot be described with Gauss modes in a simple way anymore, but is best described in terms of tilted plane waves, called Fourier modes. The beam quality and mode spectra depending on the applied current and the temperature of the VCSEL are investigated. Two-dimensional measurements of the near and the far field are combined with power and spectral measurement to characterize the VCSEL. Polarization and Fourier filtering are used to examine the spatially-dependent emission in detail. A rich dynamic in the angular emission profile for large-area VCSELs is observed and can be explained by considering the residual reflections from the AR-coated substrate-air interface and thermal effects. The presented theoretical model simulates the dynamics of the angular emission. The calculated angular and spectral profiles match the experimental observations very well over the whole parameter range. The influence of the active area is studied for diameters of the oxide aperture from 20 up to 300 &mu;m. For smaller diameters diffraction effects become more dominant, the Fresnel number is reduced and the emission spectrum gets closer to the Gauss mode description.
Expression and distribution of CD9 in myelin of the central and peripheral nervous systems. (1996)

CD9 is a member of the newly identified tetra-membrane-spanning protein family. We show here that CD9 is a constituent of myelin in the central and peripheral nervous systems. Expression of CD9 was detected in human cerebral white matter and sciatic nerve by Northern and Western blotting. Myelin in the central and peripheral nervous systems was strongly stained with a monoclonal antibody against human CD9 antigen in paraffin-embedded sections. CD9 was detected in adult nervous tissue but not in developing brain at less than 20 weeks of gestation. Immunohistochemical studies indicated that expression of CD9 is correlated with myelination and is somewhat delayed compared with expression of myelin basic protein, a major component protein of myelin. In the central nervous system, CD9 was detected along the outermost membrane of compact myelin but not inside compact myelin or the periaxonal region. Although the membrane-anchored form of heparin-binding epidermal-growth-factor-like growth factor (proHB-EGF), which is identical to the diphtheria toxin receptor, forms a complex with CD9 in some human and monkey cell lines, proHB-EGF was not detected in myelin immunocytochemically. The distribution of CD9 in the outer surface of myelin and its relatively late developmental appearance suggest that CD9 may interact with the extracellular matrix or cell adhesion molecules and participate in the maintenance of the entire myelin sheath.
Side docking: an alternative docking method for gynecologic robotic surgery. (2011)

The authors propose an alternative method of robotic docking for gynecologic surgery. In this side-docking method, the robot is docked at an approximately 45° angle to the lower torso, aligned with the outer border of either the left or right stirrup, depending on the surgeon's preference for left or right side-docking. The remainder of the patient and trocar setup is similar to traditional docking. The authors have had an excellent experience with this method as there does not seem to be an increased risk of robotic arm collision as long as the surgeon respects the basic principle of maintaining at least an 8- to 10-cm distance between each of the instrument ports. The significantly improved access to the vagina and perineum may facilitate robotically assisted gynecologic surgical procedures and reduce assistant fatigue and the potential for injury due to a collision with the robotic arms.
Growth Hormone Suppression of Apoptosis in Preovulatory Rat Follicles and Partial Neutralization by Insulin-Like Growth Factor Binding Protein1 (1995)

A growing body of evidence suggests that growth hormone (GH) plays a role in regulating ovarian function by augmenting gonadotropin stimulation of granulosa cell differentiation and folliculogenesis. The majority of follicles in the mammalian ovary do not ovulate, but instead undergo a degenerative process (atresia) involving apoptotic cell death. The objective of the present study was to investigate the role of GH in regulating follicle apoptosis and to determine whether or not insulin-like growth factor-I (IGF-I) mediates GH action in this process. Preovulatory follicles obtained from eCG-primed rats were cultured for 24 h in serum-free conditions with or without hormone treatments. After culture, follicular apoptotic DNA fragmentation was analyzed by autoradiography of size-fractionated DNA labeled at 3' ends with [32P]dideoxy-ATP. Culture of preovulatory follicles resulted in a spontaneous onset of apoptotic DNA fragmentation that was suppressed by ovine GH (oGH) in a dose-dependent manner, reaching a maximum of 65% suppression. To rule out the effect of residual gonadotropin in the oGH preparation, follicles were also cultured with recombinant bovine growth hormone (rbGH). Like oGH, rbGH suppressed apoptotic DNA fragmentation. Our earlier study indicated that hCG and FSH treatment also suppress apoptosis in the present model system, but no additive effect of GH and either hCG or FSH on the suppression of apoptosis was observed. To determine whether the observed effect of GH action on follicle apoptosis is mediated by IGF-I, three types of studies were carried out.(ABSTRACT TRUNCATED AT 250 WORDS)
Preparation of Substituted Enol Derivatives From Terminal Alkynes and Their Synthetic Utility (2008)

Stereodefined enol derivatives of aldehydes are prepared from terminal alkynes. Specifically, terminal alkynes are known to undergo Cp2ZrCl2-catalyzed methylalumination. Here, we show that the resultant vinylalanes can be oxygenated with peroxyzinc species to generate trisubstituted enolates. Electrophilic trapping with carboxylic anydrides or silyl triflates yields trisubstituted enol esters or silanes, respectively. The tandem carbometalation/oxygenation tolerates free and protected alcohols, heterocycles, olefins, and nitriles. Stereodefined enol esters can undergo asymmetric dihydroxylation to yield optically active alpha-hydroxy aldehydes. Reduction with NaBH4 provides the diols of 1,1-disubstituted olefins in excellent ee. An application of this methodology to the enantioselective synthesis of the insect pheromone frontalin is presented. Finally, alpha-hydroxy aldehydes are shown to undergo homologation to a terminal alkyne, reductive amination, oxidation and olefination. Preliminary results indicate that tandem carbometalation/amination can be accomplished with azodicarboxylates. In this way, ene-hydrazines are formed in excellent yield.
Characterization of atrial lesion safety and efficacy utilizing a circular catheter and the IRE generator with an in vivo porcine model (2021)

Abstract Funding Acknowledgements Type of funding sources: Other. Main funding source(s): Biosense Webster, Inc. Introduction/Objectives: Pulsed field ablation (PFA) is a non-thermal ablative method that delivers high voltage, very-short duration pulses that cause pore formation in the cytoplasmic membrane and cell death. The tissue selectivity of PFA is expected to reduce the risk of collateral tissue injury compared to radiofrequency catheter ablation (RFCA), while maintaining effectiveness. The objective of this study was to perform pulmonary vein (PV) isolation in a porcine model to characterize the safety and performance of a novel, fully-integrated biphasic PFA system. The system is comprised of a multi-channel generator, a variable loop circular catheter, and an integrated irreversible electroporation (IRE) mapping software module. Methods The study evaluated safety and efficacy of IRE in 8 healthy swine. First, to evaluate safety, multiple ablations were performed at various cardiac structures, including within the lumen of the right pulmonary vein (RIPV), at the right superior pulmonary vein (RSPV) ostium, and adjacent to the esophagus. Second, to evaluate efficacy, animals were recovered and followed for 30 (±3) days, then re-mapped. Gross pathological and histopathological examinations were performed to assess for procedural injury, chronic thrombosis, tissue ablation, depth of penetration, healing, and level of inflammatory response. Results All 8 swine survived for the 30 (±3) day follow up (FU) period. There were no acute (day of procedure) incidents of pulmonary vein narrowing of &amp;gt;70%, nor at 30 d follow-up (FU), even when ablation was purposefully performed directly deep to the ostium of the vein. No injury was seen grossly or histologically in the adjacent esophagus. All PVs were durably isolated as confirmed by bidirectional block at the 30 (±3) day re-map procedure, and histological examination showed complete, transmural necrosis around the entire circumference of the ablated section of the right PVs [Figure]. Conclusion(s): This pre-clinical evaluation of a fully integrated PFA system demonstrated effective and durable ablation of cardiac tissue and PV isolation with no collateral damage to adjacent structures. Notably, histological staining confirmed complete transmural cell necrosis around the circumference of the ostial PV at 30 days. Abstract Figure. PVI maps (A) histology (B) and safety(C)
High-Performance Collision-Induced Dissociation of Peptide Ions Formed by Matrix-Assisted Laser Desorption/Ionization in a Quadrupole Ion Trap Mass Spectrometer (1995)

A modified ion trap detector has been utilized to obtain high-performance collision-induced dissociation (CID) mass spectra of peptide ions formed by matrix-assisted laser desorption/ionization (MALDI). MALDI ions are trapped while increasing the fundamental radio frequency field, obviating the need for elevated helium gas pressures. Molecular ion isotopic clusters are then isolated by a reverse-forward-reverse scan sequence. A single species within the isotopic cluster (generally the monoisotopic mass) is then selected for activation. Finally, modulation of the amplitude of the resonant excitation voltage on the end-cap electrodes, used previously to improve mass calibration in normal mass spectra, is now utilized to provide high mass accuracy for the product ions. The CID mass spectra of several protonated and sodium-cationized peptides are presented and are often characterized by a series of rearrangement ions that can be utilized in the determination of amino acid sequences.
Operating characteristics of a clamp klystron oscillator with a sloping cavity at W-band (2020)

We present the design of an oscillator that is an evolution of our previously proposed “clamp klystron.” In this new embodiment, we utilize sloping cavities and increase the operating frequency to 94 GHz and 100 GHz (W-band). In this study, we utilized the UNIPIC particle-in-cell code. Simulations confirmed that this new oscillator with one sloping “buncher” cavity and one sloping “catcher” cavity with an inclination angle of 5° and shaped like a “clamp” produces 700 kW output power with an efficiency of 7.1% at 94 GHz when powered using an applied voltage U = 90 kV and beam current 110 A. When one sloping “buncher” cavity and one sloping “catcher” cavity are utilized with an inclination angle of 15°, the oscillator produces 270 kW output power with 3.0% efficiency at 100 GHz when powered using the same electron beam parameters. If two oscillators with sloping cavities along the z-axis are combined serially, then the output power can be as high as 800 kW with 8.0% efficiency at 100 GHz. This new oscillator design can be a promising approach to high power millimeter wave source designs at W-band and higher frequencies.
Brain and Retinal Pericytes: Origin, Function and Role (2016)

Pericytes are specialized mural cells located at the abluminal surface of capillary blood vessels, embedded within the basement membrane. In the vascular network these multifunctional cells fulfil diverse functions, which are indispensable for proper homoeostasis. They serve as microvascular stabilizers, are potential regulators of microvascular blood flow and have a central role in angiogenesis, as they for example regulate endothelial cell proliferation. Furthermore, pericytes, as part of the neurovascular unit, are a major component of the blood-retina/brain barrier. CNS pericytes are a heterogenic cell population derived from mesodermal and neuro-ectodermal germ layers acting as modulators of stromal and niche environmental properties. In addition, they display multipotent differentiation potential making them an intriguing target for regenerative therapies. Pericyte-deficiencies can be cause or consequence of many kinds of diseases. In diabetes, for instance, pericyte-loss is a severe pathological process in diabetic retinopathy (DR) with detrimental consequences for eye sight in millions of patients. In this review, we provide an overview of our current understanding of CNS pericyte origin and function, with a special focus on the retina in the healthy and diseased. Finally, we highlight the role of pericytes in de- and regenerative processes.
Efficient Modeling of Charge Trapping at Cryogenic Temperatures—Part II: Experimental (2021)

We present time-zero characterization and an investigation on bias temperature instability (BTI) degradation between 4 and 300 K on large area high- <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${k}$ </tex-math></inline-formula> CMOS devices. Our measurements show that negative BTI (NBTI) on pMOSFETs freezes out when approaching cryogenic temperatures, whereas there is still significant positive BTI (PBTI) degradation in nMOSFETs even at 4 K. To explain this behavior, we use an efficient implementation of the quantum mechanical nonradiative multiphonon charge trapping model presented in Part I and extract two separate trap bands in the SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> and HfO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> layer. We show that NBTI is dominated by defects in the SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> layer, whereas PBTI arises mainly from defects in the HfO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> layer, which are weakly recoverable and do not freeze out at low temperatures due to dominant nuclear tunneling at the defect site.