gebhart/patrepeval huggingface dataset:
Highly efficient planar perovskite solar cells through band alignment engineering (2015)

Planar perovskite solar cells exhibit a conduction band misalignment of the perovskite with TiO 2 , but not with SnO 2 . The system using the latter yielded power conversion efficiencies over 18%.
Supplementary Figure 1 from Depletion of Dendritic Cells Delays Ovarian Cancer Progression by Boosting Antitumor Immunity (2023)

Supplementary Figure 1 from Depletion of Dendritic Cells Delays Ovarian Cancer Progression by Boosting Antitumor Immunity
DESIGN OF A POWER CONTROL UNIT DEDICATED TO GAS SENSORS BASED ON MICROHOTPLATE PLATFORM (2003)

International audience
Techniques and algorithms in coherent detection (2010)

Complex interaction among optical signal distortions, analog component characteristics, and digital signal processing algorithms can give rise to significant performance degradation in the coherent system performance. Two topics are introduced as examples of such phenomena.
An online intervention to maintain physical activity levels in COPD patients after pulmonary rehabilitation (2016)

Background: 
Physical activity (PA) is an important self-care behavior for patients with Chronic Obstructive Pulmonary Disease (COPD). Pulmonary rehabilitation (PR) is designed to improve exercise capacity through PA of COPD patients. However, after PR, PA levels often decrease quickly. The aim of this study was to evaluate an online self-regulation intervention to promote maintenance of PA after PR. 
Methods: 
A randomized controlled trial with an intervention group (IG; n=20) and a no-intervention control group (CG;n=20). All receive an accelerometer for the entire study period; 2-4 week pre-PR baseline, 8-16 weeks PR, and 8 weeks at home. Only the IG receives the online intervention at home, comprising for example feedback on activity per day, tagging activities carried out per day and active coaching. Patients fill out questionnaires about determinants of health behavior at start PR, end PR and study end.
Findings: 
Currently, 26 patients are enrolled in the study; 15 in IG (mean age 62.7y; 7 males; baseline period PA: 399.3±167.8 Kcal/day), and 11 in CG (mean age 61.1y; 7 males, 457.5±180.8 Kcal/day). On average, participants wear the accelerometer 5-6 (sd=1.7) days/week. At home, IG patients (n=8) tagged on average 10.6 (sd=4.6) activities per day, of which the majority was performed indoors (8.9; sd=4.5). 
Discussion: 
COPD patients showed a high compliance to wearing the accelerometer daily, and visiting the coaching-website for identifying their activities. After completion of the trial, statistical analyses will be carried out to study the effect of the intervention on PA and psycho-social situation of patients.
Phenotypic Diversity and Altered Environmental Plasticity in Arabidopsis thaliana with Reduced Hsp90 Levels (2007)

The molecular chaperone HSP90 aids the maturation of a diverse but select set of metastable protein clients, many of which are key to a variety of signal transduction pathways. HSP90 function has been best investigated in animal and fungal systems, where inhibition of the chaperone has exceptionally diverse effects, ranging from reversing oncogenic transformation to preventing the acquisition of drug resistance. Inhibition of HSP90 in the model plant Arabidopsis thaliana uncovers novel morphologies dependent on normally cryptic genetic variation and increases stochastic variation inherent to developmental processes. The biochemical activity of HSP90 is strictly conserved between animals and plants. However, the substrates and pathways dependent on HSP90 in plants are poorly understood. Progress has been impeded by the necessity of reliance on light-sensitive HSP90 inhibitors due to redundancy in the A. thaliana HSP90 gene family. Here we present phenotypic and genome-wide expression analyses of A. thaliana with constitutively reduced HSP90 levels achieved by RNAi targeting. HSP90 reduction affects a variety of quantitative life-history traits, including flowering time and total seed set, increases morphological diversity, and decreases the developmental stability of repeated characters. Several morphologies are synergistically affected by HSP90 and growth temperature. Genome-wide expression analyses also suggest a central role for HSP90 in the genesis and maintenance of plastic responses. The expression results are substantiated by examination of the response of HSP90-reduced plants to attack by caterpillars of the generalist herbivore Trichoplusia ni. HSP90 reduction potentiates a more robust herbivore defense response. In sum, we propose that HSP90 exerts global effects on the environmental responsiveness of plants to many different stimuli. The comprehensive set of HSP90-reduced lines described here is a vital instrument to further examine the role of HSP90 as a central interface between organism, development, and environment.
P8: P4 With Predictable Packet Processing Performance (2020)

Data plane programmability brings network flexibility to a new level. However, it introduces the complexity of the data path's program as a new factor that influences packet forwarding latency and thus devices' performance. Accurate identification of the relation between data path complexity and packet forwarding latency enables the design and management of networks with predictable performance. In this article, we leverage the characteristics of P4 programming language to provide a method for estimating the packet forwarding latency as a function of the data path program. We analyze the impact of different P4 constructs on packet processing latency for three state-of-the-art P4 devices: Netronome SmartNIC, NetFPGA-SUME, and T4P4S DPDK-based software switch. Besides comparing the performance of these three targets, we use the derived results to propose a method for estimating the average packet latency, at compilation time, of arbitrary P4-based network functions implemented using the surveyed P4 constructs. The proposed method is finally validated using a set of realistic network functions, which shows that our method estimates the average packet latency with sub-microsecond precision.
Patterned Growth of Large Oriented Organic Semiconductor Single Crystals on Self-Assembled Monolayer Templates (2005)

This work demonstrates a method for inducing site-specific nucleation and subsequent growth of large oriented organic semiconductor single crystals using micropatterned self-assembled monolayers (SAMs). We demonstrate growth of oriented, patterned, and large organic semiconductor single crystals for potential use in organic electronic devices. The control over multiple parameters in a single system has not yet been reported. The ability to control various aspects of crystal growth in one system provides a powerful technique for the bottom-up fabrication of organic single-crystal semiconductor devices.
Microphase structure of solvent-cast diblock copolymers and copolymer-homopolymer blends containing spherical microdomains (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMicrophase structure of solvent-cast diblock copolymers and copolymer-homopolymer blends containing spherical microdomainsFrank S. Bates, C. V. Berney, and R. E. CohenCite this: Macromolecules 1983, 16, 7, 1101–1108Publication Date (Print):July 1, 1983Publication History Published online1 May 2002Published inissue 1 July 1983https://pubs.acs.org/doi/10.1021/ma00241a011https://doi.org/10.1021/ma00241a011research-articleACS PublicationsRequest reuse permissionsArticle Views484Altmetric-Citations99LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Treatment, survival, and costs of laryngeal cancer care in the elderly (2013)

2c. Laryngoscope, 128:1103-1112, 2018.
Research and Study of Low-cost and Reliable Materials for Anode and Cathode Electrodes in Bioelectrochemical Systems (BESs): Scale Up of Materials for Real Application (2014)

Microbial fuel cell (MFC) is a bioelectrochemical capable of oxidizing organics compounds and generating electricity simultaneously. The ultimate goal would be to realize a low cost treatment system that would work in self-sustainable. In order to achieve that, our groups are moving towards materials study, characterization, modification and development and optimization with the vision of scaling up BES. Several sets of anodes carbonaceous and metallic materials have been investigated. Carbonaceous materials have been investigated and functionalized with chemical and electrochemical technique in order to increase oxygen and nitrogen functional groups that allow faster and higher bacteria attachment enhancing the biofilm electro-activity and electrons generation. Unfortunately, carbonaceous materials are very expensive and not enough robust to be deployed in long terms operation. As alternative, stainless steel (SS304) commercially available plain sheet has been investigated achieving similar performances compared to carbonaceous-based electrodes. The establishment of strictly anaerobic conditions in a short amount of time guaranteed also the conditions necessary to avoid metal corrosion. SS304 looks to be promising for large-scale applications due to the materials robustness and very reduced cost (order of magnitudes lower than carbonaceous-based groups). Further studies are currently in progress towards the direction of optimizing the SS304 material adding functional groups, hierarchically organized carbon structures and protecting the SS from long term possible deterioration and corrosion. Several sets of cathodes have been deployed also in order to replace the more expensive and utilized platinum and guarantee long terms conditions. Cathodes based on cheap and high surface area activated carbon has been deployed for treating wastewaters. Other efficient, highly active and low cost catalysts based on non-PGM catalysts have been also studied with high performances and actually better behavior of platinum in SCMFC due to the establishment of highly alkaline conditions in proximity of the cathode. Moreover, those catalysts showed a better resistance to get pollutants from toxic compounds naturally present into wastewater. The low cost, high performance and reduced possibility to get poisoned make non-PGM a suitable choice of catalysts to be deployed in BESs.
Preparation of 2‐Arylindole‐4‐carboxylic Amide Derivatives. (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Design and Synthesis of 4-Heteroaryl 1,2,3,4-Tetrahydroisoquinolines as Triple Reuptake Inhibitors (2014)

A series of 4-bicyclic heteroaryl 1,2,3,4-tetrahydroisoquinoline inhibitors of the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT) was discovered. The synthesis and structure-activity relationship (SAR) of these triple reuptake inhibitors (TRIs) will be discussed. Compound 10i (AMR-2), a very potent inhibitor of SERT, NET, and DAT, showed efficacy in the rat forced-swim and mouse tail suspension models with minimum effective doses of 0.3 and 1 mg/kg (po), respectively. At efficacious doses in these assays, 10i exhibited substantial occupancy levels at the three transporters in both rat and mouse brain. The study of the metabolism of 10i revealed the formation of a significant active metabolite, compound 13.
Automated analysis of 16-color polychromatic flow cytometry data maps immune cell populations and reveals a distinct inhibitory receptor signature in systemic sclerosis (2015)

Background. The phenotypic profiles of both peripheral blood and tissue-resident immune cells have been linked to the health status of individuals with infectious and autoimmune diseases, as well as cancer. In light of the promising clinical trial results of agents that block the Inhibitory Receptor (IR) Programmed Death 1 (PD-1) axis, novel flow cytometric panels that simultaneously measure multiple IRs on several immune cell subsets could provide the distinct IR signatures to target in combinational therapies for many disease states. Also, due to the paucity of human samples, larger (14+ color) ‘1-tube’ panels for immune cell characterization ex vivo are of a high value in translational studies. Development of fluorescent-based panels offer several advantages as compared with analogous mass cytometric methods, including the ability to sort multiple populations of interest from the sample for further study. However, automated platforms of multi-dimensional single cell analysis that allow objective and comprehensive population characterization are severely underutilized on data generated from large polychromatic panels. Methods. A 16-color flow cytometry (FCM) panel was developed and optimized for the simultaneous characterization and purification of multiple human immune cell populations on a 4- laser BD FACSARIA II cell sorter. FCM data of samples obtained from healthy subjects and individuals with systemic sclerosis (SSc) were loaded into Cytobank cloud, then compensated and analyzed with SPADE clustering algorithm. The viSNE algorithm was also employed to compress the data into a 2D map of phenotypic space that was subsequently clustered using SPADE. For comparison, the FCM data were also analyzed manually using FlowJo software. Results. Our novel 16-color panel recognizes CD3, CD4, CD8, CD45RO, CD25, CD127, CD16, CD56, γδTCR, vα24, PD-1, LAG-3, CTLA-4, and TIM-3; it also contains a CD1d-tetramer and a live-dead dye (with CD19 and CD14 included as a combined dump channel). This panel allows combinational IR signatures to be determined from CD4+ T, CD8+ T, Natural Killer (NK), invariant Natural Killer (iNKT), and gamma delta (γδ) immune cell subsets within one sample. We have successfully identified all subsets of interest using automatic SPADE and viSNE algorithms integrated into Cytobank services, and demonstrated a distinctive phenotype of IR distribution on healthy versus systemic sclerosis subject groups. Conclusions. Methods of automatic analysis that were originally developed for processing multi-dimensional mass cytometry can be applied to polychromatic FCM datasets and provide robust results, including subset identification and distinct IR signatures in healthy compared to diseased subject groups.
Advancing photonic design with machine learning (2022)

Discovering unconventional optical designs via machine-learning promises to advance on-chip circuitry, imaging, sensing, energy, and quantum information technology. In this talk, photonic design approaches and emerging material platforms will be discussed showcasting machine-learning-assisted topology optimization for optical metasurface designs for applications in thermophotovoltaics, reflective optics and more.
Temperature Measurement of the Mold and Samples on the Pluse Plasma Sintering. (1998)

The plasma activated sintering (PAS) is a kind of hot pressing method. During pressing, the electric current flows in the mold (die and punches) and powder sample. There are two types of electric current. The surface of the powder is cleaned and activated by activating electric current. The mold and powder sample is heated by sintering electric current due to the Joule effect. It is well-known that the temperature of a sample is closely related to the sintered materials' properties and there is a favored temperature for sintering the powder. The temperature is measured either by thermocouples in the mold or by an infrared optical thermometer focused on the mold surface, but these measurements do not give the temperature of the sample in the mold itself. Sometimes the real temperature of samples is higher than the measured temperature. This temperature difference depends on the material properties, especially the electric resistance and the thickness of the sample. The authors studied experimentally the relation between the temperature difference and the electric resistance using dummy samples made of stainless steel, graphite and alumina.
Effective area of a bent polarizing double-clad Yb-doped photonic crystal fiber (2011)

The bending influence on the effective area of a polarizing double-clad Yb-doped photonic crystal fiber has been numerically investigated. The fiber design robustness to air-hole diameter and core refractive index changes has been also demonstrated.
Abstract 1571: Developing antigen-specific Th1 epitope based vaccines by excluding immunosuppressive peptide sequences (2012)

Abstract We have determined that IGFBP-2 is immunogenic in ovarian cancer. Our aim is to develop a multi-epitope vaccine that will elicit Th1 immunity to IGFBP-2. Antigen specific Th1 can modulate the tumor microenvironment to enhance cross priming, supporting the proliferation of cytotoxic T cells which are capable of eradicating ovarian cancer cells. Although some clinical benefit has been demonstrated with this strategy, recent ex vivo analyses of human PBMC have described the presence of antigen-specific CD4+ T regulatory cell (Tregs) in cancer patients that were not detected in healthy individuals. Thus, we questioned if we could optimize our vaccine to include only Th1-stimulating epitopes. Using a combined scoring system from five algorithms for predicting class II binding to determine Th epitopes, we identified 14 IGFBP-2 peptides. Th1 immunogenicity (IFN-gamma) and potential immunosuppression (IL-10) was evaluated by ELISPOT for 40 different donors. Twenty-two percent of the donors only responded with IL-10 secretion to any peptide, 22% only responded with IFN-gamma and 53% of the patients had a mixed IFN-gamma and IL-10 response. To determine which peptides would induce a predominantly Th1 response in the greatest number of people, we used a ratio of IFN-gamma to IL-10 and analyzed both the magnitude and frequency of ELISPOT responses for each of peptides using the following algorithm: (corrected mean SPW) x (percent of responding donors). The peptides were then ranked from highest IL-10 response to highest IFN-gamma response. Interestingly, 6 of the 14 peptides demonstrated a preference to secrete IFN-gamma over IL-10 and are only located in the N-terminus (amino acids 1-163) of IGFBP-2; the remaining potentially immunosuppressive peptides are located in the C-terminus (amino acids 164-328). Vaccination with p1-163 in MMTV-neu mice demonstrated a robust Th1 response (p=0.03) and concomitant inhibition of tumor growth by 70% compared to adjuvant only control animals, p164-328-vaccinated or full length protein-vaccinated mice (p&amp;lt;0.001 for all). Vaccination with p164-328 or full length protein did not inhibit tumor growth. These data suggest that more effective vaccines can be designed when both Th1 epitopes and immunosuppressive epitopes are screened simultaneously and epitopes that are most likely to induce robust Th1 responses in the majority of individuals can be identified and included as vaccine components. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 1571. doi:1538-7445.AM2012-1571
Hepatocyte growth factor mobilizes non-bone marrow-derived circulating mesoangioblasts (2010)

Hepatocyte growth factor induces mobilization of non-haematopoietic progenitor cells with a cardiac repair capacity. This newly identified function together with the known pleiotrophic effects of HGF makes HGF an attractive therapeutic option for the treatment of ischaemic heart disease.
Total Synthesis of Glycohexa- and Nonaosyl Ceramide with a Sialyl Lea and Sialyl Dimeric Lea Sequence (1998)

Abstract A total synthesis of tumor-associated glycolipid antigen sialyl Lea, and a first total synthesis of glycononaosyl ceramide with a dimeric Lea sequence are described. Regio-and stereoselective coupling of sialyl donor 12 with suitably protected Lea trisaccharide fluoride 17 was performed by orthogonal glycosylation to give the expected tetrasaccharide 18 in good yield. Glycosylation of its acetate 19 with lactose derivative 8 by use of Cp2HfCl2-AgOTf as a promoter, gave the desired hexasaccharide 20. On the other hand, glycosylation between sialyl Lea tetrasacchande donor 34 and Lea pentasaccharide acceptor 35 under the agency of PhSeOTf afforded the desired nonasaccharide 36. After replacement of the benzyl groups in 20 and 36 by acetyl groups, the anomeric acetate was transformed into the α-trichloroacetoimidates 23, 39 and the fluoride derivative 40. The crucial couplings of 23, 39 and 40 with azidosphingosine derivative 3 or ceramide derivative 4 were executed to afford β-glycosides 24 and 41. Compound 24 was converted to 26 via reduction of the azide group followed by N-acylation. The target gangliosides 1 and 2 were obtained from 26 and 41, respectively, by selective cleavage of the methyl ester, conversion of the N-phthalimido group to the N-acetamido group, and O-deprotection.
Genetic engineering of Lactobacillus (1986)

Technological developments in the genetic engineering of Lactobacillus sp. to enhance and stabilize its desirable characteristics in fermentation (e.g., metabolic conversion of glucose to lactic acid) are reviewed. Classical mutagenesis and selection techniques for generating Lactobacillus mutants are discussed, as well as the plasmid biology of lactic acid bacteria. The development of a specific genetic engineering system for Lactobacillus sp. is described and illustrated. The potential objectives and limitations for genetic manipulation for food industry applications also are discussed.(wz)
How Relevant Is the Turing Test in the Age of Sophisbots? (2019)

Popular culture has contemplated societies of intelligent machines for generations. Today, we find ourselves at the doorstep of technology that can at least simulate thinking, feeling, and other behaviors. The question is: Now what?
Mathematics behind the Fractional-order Smith Chart (2011)

This paper derives the theory for a fractional order Smith chart and provides a comparison between the impedance and admittance fractional order Smith charts. Basic chart features such as boundaries, critical points, peak values, matching (unity) circle, and the central angle are investigated and compared. Mathematical analysis for these basic features and standard Smith chart functions is also described. This Smith chart can be used to study the scattering parameters in fractional-order RF designs. In addition, it may be used for inverse problems whose models depend on fractional-order electrical elements.
Nitrate-Reductase Deficients in the Progeny After Selfing Complemented Somatic Hybrids of Nicotiana Plumbaginifolia Mutants (1983)

Interest in nitrate assimilation initiated experiments which led to the isolation of a number of nitrate-reductase /NR/ deficient mutants in flowering plants.