gebhart/patrepeval huggingface dataset:
Resolvin D1 improves allograft osteointegration and directly enhances osteoblasts differentiation (2023)

Repeated administrations of RvD1 promote bone regeneration <i>via</i> a dual mechanism: directly, <i>via</i> enhancement of osteoblasts' differentiation and indirectly, through reduction of osteoclastogenesis and RANKL/OPG ratio. This suggests that RvD1 may be a potential therapeutic bioagent for osseous regeneration following allograft implantation.
1773: Primary Prostate Cryoablation: Results from 1198 Patients Tracked with the Cold Registry (2007)

You have accessJournal of UrologyModerated Poster 56, Wednesday, May 23, 2007 10:00 am - 12:00 pm1 Apr 20071773: Primary Prostate Cryoablation: Results from 1198 Patients Tracked with the Cold Registry J. Stephen Jones, Bryan J. Donnelly, Louis L. Pisters, Franco Lugnani, and Aaron E. Katz J. Stephen JonesJ. Stephen Jones More articles by this author , Bryan J. DonnellyBryan J. Donnelly More articles by this author , Louis L. PistersLouis L. Pisters More articles by this author , Franco LugnaniFranco Lugnani More articles by this author , and Aaron E. KatzAaron E. Katz More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)31961-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1773: Primary Prostate Cryoablation: Results from 1198 Patients Tracked with the Cold Registry." The Journal of Urology, 177(4S), pp. 589–590 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 177Issue 4SApril 2007Page: 589-590 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information J. Stephen Jones More articles by this author Bryan J. Donnelly More articles by this author Louis L. Pisters More articles by this author Franco Lugnani More articles by this author Aaron E. Katz More articles by this author Expand All Advertisement PDF DownloadLoading ...
Hybrid Angular- and Energy-Dispersive X-ray Diffraction Computed Tomography (2018)

X-ray diffraction is a material-specific technique, the results of which can be used as a material fingerprint to identify unknowns. In this paper we present an adaptation to a novel hybrid angular- and energy-dispersive X-ray diffraction technique, which, until now, has been limited in utility by sample thickness. Computed tomography techniques have been applied to spatially resolve the origin of the scattering signals and to reconstruct the diffraction pattern in each pixel. 2D cross-correlation has been used to compare the reconstructed data to a library of standards as a means of identifying the material present.
Bulky Titanium Bis(phenolate) Complexes as Novel Initiators for Living Anionic Polymerization of ε-Caprolactone (2000)

Bulky bis(phenolate) complexes of titanium alcoholates were found to initiate living polymerization of ε-caprolactone, affording a polyester with a narrow molecular weight distribution. By changing the initial monomer-to-initiator mole ratio, the molecular weight of the polymer was controlled over a wide range. 1H NMR studies on the produced polymer showed the presence of an alkoxy group originating from the initiator at the polymer terminal, indicating that the polymerization takes place at the titanium alcoholate bond of the initiator. Use of titanium complexes prepared with nonbridged hindered phenols or a less bulky bisphenol resulted in a poorly controlled chain growth or no polymerization.
Emerging resistive memories for low power embedded applications and neuromorphic systems (2015)

In this work, we will focus on the role that new nonvolatile resistive memory technologies can play in emerging fields of application, such as non-volatile logic circuits or neuromorphic circuits, to save energy and increase performance. Concerning the introduction of non-volatile functionalities at the logic level, we will demonstrate hybrid CMOS logic plus ReRAM (specifically CBRAM and OXRAM) circuits for ultra low power FPGA and fixed-logic IC design, as Non Volatile Flip-Flops. Concerning neuromorphic circuits, we will focus on the emulation of synaptic plasticity effects with resistive memory synapses. We will present large-scale energy efficient neuromorphic systems based on ReRAM as stochastic-binary synapses. Prototype applications such as complex visual- and auditory-pattern extraction will be also discussed using feedforward spiking neural networks.
Semiconductor specialty technologies in IOT era (2015)

Summary form only given. Internet of Things (IoT) has caught a lot of attention recently due to tremendous business opportunities. In this talk, the speaker intends to give the historical figures in PC/NB and smartphones at first, and then bring in the overall view of IOT. And then it will deploy to various semiconductor technology challenges and opportunities for IOT applications, including micro-controllers, micro-processors, wireless technologies, sensors, power managements, etc. The audience should expect to get clearer pictures of devices in IOT from this talk.
Dynamic Asphaltene-Stearic Acid Competition at the Oil–Water Interface (2018)

Interfacial tension (IFT) is one of the major parameters which govern the fluid flow in oil production and recovery. This paper investigates the interfacial activity of different natural surfactants found in crude oil. The main objective was to better understand the competition between carboxylic acids and asphaltenes on toluene/water interfaces. Dynamic IFT was measured for water-in-oil pendant drops contrary to most studies using oil-in-water drops. Stearic acid (SA) was used as model compound for surface-active carboxylic acids in crude. The influence of concentration of these species on dynamic IFT between model oil and deionized water was examined. The acid concentrations were of realistic values (total acid number 0.1 to 2 mg KOH/g oil) while asphaltene concentrations were low and set between 10 and 100 ppm. In mixtures, the initial surface pressure was entirely determined by the SA content while asphaltenes showed a slow initial diffusion to the interface followed by increased adsorption at longer times. The final surface pressure was higher for asphaltenes compared to SA, but for binaries, the final surface pressure was always lower than the sum of the individuals. At high SA concentration, surface pressures of mixtures were dominated entirely by the SA, although, Langmuir isotherm analysis shows that asphaltenes bind to the interface 200-250 times stronger than SA. The surface area/molecule for both SA and asphaltenes were found to be larger than the values reported in recent literature. Various approaches to dynamic surface adsorption were tested, showing that apparent diffusivity of asphaltenes is very low, in agreement with other works. Hence, the adsorption is apparently under barrier control. A possible hypothesis is that at the initial phase of the experiment and at lower concentration of asphaltenes, the interface is occupied by stearic acid molecules forming a dense layer of hydrocarbon chains that may repel the asphaltenes.
The agreement and trend ability of a Non-invasive Continuous Cardiac Output Measurement Method Utilizing ECG and SpO2 Pulse Wave against Echo Doppler during Exercise (2013)

A new technology called estimated continuous cardiac output (esCCO) uses pulse wave transit time (PWTT) obtained from an electrocardiogram and pulse oximeter to measure cardiac output (CO) noninvasively and continuously. This study was performed to evaluate the accuracy of esCCO during exercise testing. We compared esCCO with CO measured by echo Doppler aortic velocity-time integral (VTIao_CO). The correlation coefficient between esCCO and VTIao_CO was r = 0.87 (n = 72). Bias and precision were 0.33 ± 0.95 L/min with a percentage error of 30.2%. And the correlation coefficient between change in esCCO and change in VTIao_CO was r = 0.75 (n = 70). The esCCO could detect change in VTIao_CO larger than 1 L/min with a concordance rate of 88.2%. The areas under ROC curves to detect VTIao_CO changes more than 15% and 30% were 0.81 and 0.91, respectively. Polar plots show that the mean polar angle was 2.2° and radial limits of agreement were ±43.6°. The trending ability of esCCO is comparable with that of currently available arterial waveform analysis methods. In this study, the validity of esCCO during exercise testing was assessed and shown to be acceptable with respect to agreement and trending ability compared with the echo Doppler.
Not Just an Athlete: The Impact of High School Coaches on the Educational Pursuit of First-year African American College Football Players (2016)

Elite high school football players face a barrage of pressures from their external environment that determine where they attend college as well as what factors, whether academic or athletic, they consider in a school. This study aims to analyze the relationship between African American high school football players, who go on to play intercollegiate football, and their high school football coaches. African American freshmen football players at a predominantly white institution in the Southwest United States were interviewed. The responses were compared and analyzed using two tenants of critical race theory (CRT): the centrality of experiential knowledge and the challenge to the dominant ideology. In an educational context, CRT utilizes storytelling and the experiences of people of color to highlight their experiences against the dominant culture in order to transform the educational environment for the benefit of marginalized people. After analyzing the interview transcriptions, the researchers found that these athletes were positively influenced by their high school coaches to perform well academically in high school, as well as to consider academics as a major point of emphasis in choosing to attend a university. Athletes developed positive relationships with their coaches, regardless of the sport in which they coached, that encouraged them to perform well academically and see college as a means to attain a degree as opposed to an avenue to professional athletics. This positive relationship contrasted some previous literature about college students that suggested that college coach–athlete relationship could be a major source of exploitation and stress for the athletes. Overall, the research found that these coaches were a source of positive influence on these student–athlete's lives athletically, personally, and academically.
Supplementary Table 1 from Differential Gene Expression Analysis Reveals Activation of Growth Promoting Signaling Pathways by Tenascin-C (2023)

Supplementary Table 1 from Differential Gene Expression Analysis Reveals Activation of Growth Promoting Signaling Pathways by Tenascin-C
Ideal gingival form with computer-generated permanent healing abutments. (2000)

Implant fixture positioning and inclination problems that result from poor osseous height, width, and ridge configuration have created difficult prosthetic tooth replacement scenarios. Options for ameliorating poor angulation are limited to the use of preangled and custom abutments. Overcoming poor angulation has been simplified by using custom vs preangled abutments because preangled abutments are limited by their standardization to a few random angles. Custom abutments can be more predictably formed to re-create the desired supporting preparation orientation and morphology. This facilitates the formation of anatomical gingival topography and coronal contours for prosthetic replacement. Cast, ceramic, and machine-milled titanium abutments have several advantages and disadvantages. A new custom abutment system that uses computer-guided manufacturing technology to machine mill custom abutments from commercially pure titanium is described. These abutments are anatomically correct, have the proper emergence anatomy, proper spatial design at the cervical margins, necessary occlusal reduction, and the proper axial angulation of ideal tooth preparations. A clinical case that illustrates implementation, with respect to the principle of stage 2 guided tissue healing, is presented.
On protective buffer policies (1994)

Studies buffering policies which provide different loss priorities to packets/cells, while preserving packet ordering (space priority disciplines). These policies are motivated by the possible presence, within the same connection, of packets with different loss probability requirements or guarantees, e.g., voice and video coders or rate control mechanisms. The main contribution of the paper is the identification and evaluation of buffering policies which preserve packet ordering and guarantee high priority packets performance (loss probability), irrespective of the traffic intensity and arrival patterns of low priority packets. Such policies are termed protective policies. The need for such policies arises from the difficulty to accurately characterize and size low priority traffic, which can generate large and unpredictable traffic variations over short periods of time. The authors review previously proposed buffer admission policies and determine if they satisfy such "protection" requirements. Furthermore, they also identify and design new policies, which for a given level of protection maximize low priority throughput.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Theoretical analysis of a method for in situ decontamination of soil containing 2,3,7,8-tetrachlorodibenzo-p-dioxin (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTheoretical analysis of a method for in situ decontamination of soil containing 2,3,7,8-tetrachlorodibenzo-p-dioxinErika J. Dougherty, Arnold L. McPeters, Michael R. Overcash, and Ruben G. CarbonellCite this: Environ. Sci. Technol. 1993, 27, 3, 505–515Publication Date (Print):March 1, 1993Publication History Published online1 May 2002Published inissue 1 March 1993https://pubs.acs.org/doi/10.1021/es00040a009https://doi.org/10.1021/es00040a009research-articleACS PublicationsRequest reuse permissionsArticle Views116Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Structure and Biosynthesis of Cetoniacytone A, a Cytotoxic Aminocarba Sugar Produced by an Endosymbiontic Actinomyces. (2002)

Cetoniacytone A (1) and some related minor components (2, 6, 7) were produced by Actinomyces sp. (strain Lu 9419), which was isolated from the intestines of a rose chafer (Cetonia aureata). The structures of the novel metabolites were established by detailed spectroscopic analysis. The absolute configuration of 1 was determined by X-ray analysis and derivatisation with chiral acids. 1 exhibits a significant cytotoxicity against selected tumor cell lines. The biosynthesis of 1 was studied by feeding 13C labelled precursors. The results suggest that the characteristic p-C7N skeleton of the aminocarba sugar is formed via the pentose phosphate pathway by cyclisation of a heptulose phosphate intermediate.
Membrane Invasion Culture System (2003)

Metastasis is the major cause of morbidity and death for cancer patients. A critical challenge to clinical and basic scientists is the development of improved prognostic methods to predict the metastatic aggressiveness of a patient's individual tumor and especially to control local invasion-a key step in the metastatic cascade. Before effective therapeutic regimens can be planned, we must invest more effort in understanding the pathogenesis of tumor cell dissemination in order to identify better targets for clinical intervention.
Known Drugs Identified by Structure-Based Virtual Screening Are Able to Bind Sigma-1 Receptor and Increase Growth of Huntington Disease Patient-Derived Cells (2021)

Huntington disease (HD) is a devastating and presently untreatable neurodegenerative disease characterized by progressively disabling motor and mental manifestations. The sigma-1 receptor (σ1R) is a protein expressed in the central nervous system, whose 3D structure has been recently determined by X-ray crystallography and whose agonists have been shown to have neuroprotective activity in neurodegenerative diseases. To identify therapeutic agents against HD, we have implemented a drug repositioning strategy consisting of: (i) Prediction of the ability of the FDA-approved drugs publicly available through the ZINC database to interact with σ1R by virtual screening, followed by computational docking and visual examination of the 20 highest scoring drugs; and (ii) Assessment of the ability of the six drugs selected by computational analyses to directly bind purified σ1R in vitro by Surface Plasmon Resonance and improve the growth of fibroblasts obtained from HD patients, which is significantly impaired with respect to control cells. All six of the selected drugs proved able to directly bind purified σ1R in vitro and improve the growth of HD cells from both or one HD patient. These results support the validity of the drug repositioning procedure implemented herein for the identification of new therapeutic tools against HD.
Photochemical reactions of cyclic sulphides (1969)

D. C. Neckers and J. DeZwaan, J. Chem. Soc. D, 1969, 813b DOI: 10.1039/C2969000813B
Progress in all-fiber components (2006)

Fiber lasers are attractive because they can avoid many problems associated with free-space optics. However, the large mode area required in high power fiber lasers and amplifiers causes several new difficulties in fiber and component design and in fusion assembly methods. Mode transformation technology allows optimization of the design of the gain fibers with independent control of the characteristics of the input and output beams. The quality of the output beam is decoupled from the mode shape in the gain fiber. Even with the desired signal properties, the high optical powers and multimode pump operation cause new issues with reliability of the fused fibers and components. To achieve high reliability operation, care must be taken to minimize and dissipate stray light.
Abstract IA05: Genomic approaches to drug discovery (2018)

Abstract It is now becoming possible to bring powerful genomic methods to bear on the process of drug discovery. This talk will illustrate 1) the use of the Connectivity Map, a large-scale effort to develop a compendium of gene expression signatures of cellular state; 2) the use of PRISM, a new multiplexed, high-throughput approach to screening cancer cell lines for anticancer activity; and 3) the use of cancer models (cell lines and patient-derived xenografts) in discovery, with particular focus on clonal drift in these models and the impact of that drift on drug sensitivity. Citation Format: Todd Golub. Genomic approaches to drug discovery [abstract]. In: Proceedings of the AACR Conference on Advances in Sarcomas: From Basic Science to Clinical Translation; May 16-19, 2017; Philadelphia, PA. Philadelphia (PA): AACR; Clin Cancer Res 2018;24(2_Suppl):Abstract nr IA05.
Microwave-to-Optical Converter based on Integrated Lithium Niobite Coupled-Resonators (2018)

We experimentally demonstrate an efficient classical microwave-to-optical converter using coupled optical microresonators on lithium niobite with Q = 2.7×106. We measure full-depth optical modulation with a 7 GHz microwave driving voltage Vrms = 70 mV.
The role of endotoxin immunity, neutrophil degranulation and contact activation in the pathogenesis of post-operative organ dysfunction (1993)

Gut mucosal hypoperfusion is associated with a poor outcome following major surgery but the pathogenetic mechanisms remain poorly understood. We have examined the relationship between gut mucosal hypoperfusion, endotoxin core antibodies (EndoCAb), neutrophil elastase alpha-1 antitrypsin complexes (NE) and components of the contact system during elective major surgery. Of the 26 patients studied 16 developed gut mucosal hypoperfusion (pHi < 7.32) by the end of surgery; of these four developed multiple organ failure (MOF) and three subsequently died. In this group there was a significant rise in NE (P< 0.005) and significant reductions in components of the contact system (factor XII, anithrombin III, prekallikrein and C1-inhibitor;P< 0.001) from immediately before surgery to 24h later. Ten patients maintained gut mucosal perfusion (pHi ≥ 7.32); none of these developed life threatening complications. In this group there was no significant increase in NE and, although there were significant reductions in some components of the contact system (P< 0.01), levels of C1-INH were not reduced. All patients demonstrated a significant reduction in both IgG and IgM EndoCAbs (P≤ 0.005) indicating exposure to endotoxin. However, the group that maintained gut mucosal perfusion had significantly higher IgG EndoCAb levels at baseline and 24 h (P≤ 0.005). These data suggest that all patients were exposed to endotoxin and that high levels of anti-endotoxin antibodies may contribute to the prevention of endotoxin-induced contact activation, neutrophil degranulation and gut mucosal hypoperfusion occurring during major surgery and thus reduce the likelihood of the development of post-operative MOF.
Short-lag spatial coherence imaging on matrix arrays, Part 1: Beamforming methods and simulation studies (2014)

Short-lag spatial coherence (SLSC) imaging is a beamforming technique that has demonstrated improved imaging performance compared with conventional B-mode imaging in previous studies. Thus far, the use of 1-D arrays has limited coherence measurements and SLSC imaging to a single dimension. Here, the SLSC algorithm is extended for use on 2-D matrix array transducers and applied in a simulation study examining imaging performance as a function of subaperture configuration and of incoherent channel noise. SLSC images generated with a 2-D array yielded superior contrast-to-noise ratio (CNR) and texture SNR measurements over SLSC images made on a corresponding 1-D array and over B-mode imaging. SLSC images generated with square subapertures were found to be superior to SLSC images generated with subapertures of equal surface area that spanned the whole array in one dimension. Subaperture beamforming was found to have little effect on SLSC imaging performance for subapertures up to 8 x 8 elements in size on a 64 × 64 element transducer. Additionally, the use of 8 x 8, 4 x 4, and 2 x 2 element subapertures provided 8, 4, and 2 times improvement in channel SNR along with 2640-, 328-, and 25-fold reduction in computation time, respectively. These results indicate that volumetric SLSC imaging is readily applicable to existing 2-D arrays that employ subaperture beamforming.