gebhart/patrepeval huggingface dataset:
Cold welding on cogged surface (2008)

La soldadura por frío entre superficies dentadas es lograda presionando una chapa de aluminio deformable fácilmente por una superficie dentada de un componente más duro. El proceso requiere la limpieza exacta de las chapas en el área de contacto. El empalme se logra solamente por grande deformación plástica del componente del aluminio, que entra entre los dientes del más duro, hecha de cobre, o de acero carbón o inoxidable. El papel presenta el modelo 2D por elemento finito del proceso: Los resultados como tensión elemental y las tensiones en el área de contacto en el componente de aluminio fueron discutidos y comparados con experimentos. Se presentan también la deformación y/o las grietas del aluminio que fluye durante presionar entre los dientes del material más duro, a diversas grados de deformación. El uso industrial más importante del proceso es en electrotécnica, para los empalmes disímiles de aluminio-cobre.-Cold welding on cogged surfaces is achieved by pressing an easy deformable sheet of aluminium on a cogged surface of a harder component. The process requires sheets accurate cleaning in the contact area, where the cold welding is expected to occur. The joint was obtained only by large plastic deformation of the aluminium component on the harder one, made from copper, or carbon/stainless steel. The paper presents the 2D Finite Element Method Model of the process; results as aluminium component elementary strain and stresses in the contact area were discussed and compared with experiments. The aluminium flowing during pressing into the harder material cogs at different deformations, its deformation or cracking are presented, as too. The process industrial application in electrotechnics, to obtaining dissimilar joints of aluminium-copper, is of high importance due to the coupled materials electric properties.
A general approach for non-coherently excited annihilation up-conversion: transforming the solar-spectrum (2008)

We demonstrate up-conversion with an external quantum yield of 3.2% realized at ultra-low excitation intensities (∼0.1 W cm−2). The bimolecular up-conversion process in our systems relies on the presence of a metastable triplet excited state, and thus has substantially different photophysical characteristics when compared with the other known methods for photon up-conversion (two-photon absorption, parametric processes, second harmonic generation, sequential multiphoton absorption, etc). Thus, we state the general requirements for the materials' parameters of the couple sensitizer/emitter for obtaining triplet–triplet annihilation up-conversion. One of the applications we suggest for active materials compositions is the achievement of energetically stepwise up-conversion of the terrestrial solar spectrum towards blue wavelengths: as such they could be used for improving the efficiency of the solar cells. Up-conversion with non-coherent excitation by sunlight with wavelengths between 550 and 700 nm is demonstrated.
US health insurance is an obstacle to disease-modifying treatments in MS (2016)

In 1993, the first disease-modifying therapy (DMT) specifically for relapsing-remitting multiple sclerosis (RRMS) was introduced, and an untreatable disease became treatable. The US Food and Drug Administration now has approved 14 DMTs in 8 classes with different mechanisms of action, administration routes, and side effects.1 This therapeutic palette allows neurologists to control RRMS in most patients.
Scanning Tunneling Microscopy Images of a Novel Dimeric Liquid Crystal on Graphite (1996)

Scanning tunneling microscopy (STM) images of a side-by-side dimeric liquid crystal adsorbed on graphite suggest an unusual structure for the monolayer. Instead of the contact with the graphite being maximized, two of the alkyl tails appear to be nearly normal to the surface. Calculations suggest that this may be due to the substitution of one of the aromatic rings in the core, which causes an alkoxy tail to prefer an orientation perpendicular to the aromatic core rather than the usual coplanar orientation. STM images taken at various bias voltages correlate strongly to the aromatic “cores” of the molecules, but do not appear to correlate to the highest occupied moleculear orbital or lowest unoccupied molecular orbital.
Improved Electrical Properties of 4H-SiC MOS Devices with High Temperature Thermal Oxidation (2019)

We reported that high oxidation temperature is attributed to break Si-C bond and release nitrogen gas to nitrogen ions over 1350°C. The capacitance-voltage characteristics of SiO 2 /4H-SiC (0001) MOS capacitors fabricated under different thermal oxidation conditions are compared. The dependence of oxidation temperature on device characteristics (such as V FB and ΔV FB ) is also analyzed. After a high temperature oxidation, the device reliability of SiC MOS is improved. Such behavior can be attributed to the reduction of the interface traps during high temperature oxidation.
Abstract 2354: Cancer vaccine development for hepatocellular carcinoma - HEPAVAC (2016)

Abstract The HEPAVAC Consortium aims to develop a highly innovative, novel cancer vaccine approach for hepatocellular carcinoma (HCC). The international project consortium consists of 9 European Partners from academia and the biotech industry with complementary and substantial expertise in developing immunotherapeutic strategies to treat cancer. The project has started in September 2013 and is supported by the European Commission's 7th Framework Program (www.hepavac.eu). HCC/normal adjacent tissue matched samples have been collected for HLA immunopeptidome analysis. 17 HCC samples from HLA-A*02+ patients and 15 samples from HLA-A*24+ patients have been analysed by mass spectrometry (LC-MS/MS). RNA-expression profiles have been established for 12 HCC samples. HLA-presentation/expression of peptides and mRNA on primary HCC samples are compared to &amp;gt;140 normal tissue samples from relevant organs (including heart, brain, lung, kidney, liver, nerve, skin etc.) from Immatics’ database. A total of 9051 HLA-A*02-restricted different tumor-associated peptides (TUMAPs) have been identified from HLA-A*02+ samples, while a total of 3286 different HLA-A*24-restricted TUMAPs have been identified from HLA-A*24+ samples. Of these, 33 HLA-A*02+ TUMAPS and 33 HLA-A*24+ TUMAPs have been validated, including peptide synthesis, immunogenicity testing and pharmaceutical evaluation. Most promising TUMAP candidates show selective expression only in HCC samples and no expression in normal tissues. In parallel, more than 6600 HLA-DR TUMAPs have been identified in Hep3B cells transfected with CIITA as well as an average of 1500 HLA-DR TUMAPs have been identified in HCC samples. A total of 16 newly identified HCC-specific epitopes have been selected for the HEPAVAC vaccine cocktail and are currently synthesized according to GMP standard. Of these, 7 are restricted to HLA- class I A*02; 5 HLA-A*24 and 4 HLA class II. In parallel, preclinical studies assessing the formulation and combination of the immunological RNA-based adjuvant (RNAdjuvant®) with peptide cocktails are underway. A multi Center phase I/II clinical trial in early HCC patients is predicted to start in July 2016. Citation Format: Sarah Kutscher, Roberto Accolla, Yuk T. Ma, Regina Heidenreich, Francesco Izzo, Alfred Koenigsrainer, Markus Loeffler, Phillip Mueller, Andrea Mayer, Hans-Georg Rammensee, Bruno Sangro, Sven Francque, Danila Valmori, Toni Weinschenk, Harpreet Singh-Jasuja, Luigi Buonaguro. Cancer vaccine development for hepatocellular carcinoma - HEPAVAC. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 2354.
Search for exclusive or semi-exclusive γγ production and observation of exclusive and semi-exclusive e+e− production in pp collisions at $ \sqrt{s}=7 $ TeV (2012)

A bstract A search for exclusive or semi-exclusive γγ production, pp → p (*) + γγ + p (*) (where p * stands for a diffractively-dissociated proton), and the observation of exclusive and semi-exclusive e + e − production, pp → p (*) + e + e − + p (*) , in proton-proton collisions at $ \sqrt{s}=7 $ TeV, are presented. The analysis is based on a data sample corresponding to an integrated luminosity of 36 pb −1 recorded by the CMS experiment at the LHC at low instantaneous luminosities. Candidate γγ or e + e − events are selected by requiring the presence of two photons or a positron and an electron, each with transverse energy E T &gt; 5 . 5 GeV and pseudorapidity | η | &lt; 2 . 5, and no other particles in the region | η | &lt; 5 . 2. No exclusive or semi-exclusive diphoton candidates are found in the data. An upper limit on the cross section for the reaction pp → p (*) + γγ + p (*) , within the above kinematic selections, is set at 1.18 pb at 95% confidence level. Seventeen exclusive or semi-exclusive dielectron candidates are observed, with an estimated background of 0 . 85 ± 0 . 28 (stat.) events, in agreement with the QED-based prediction of 16 . 3 ± 1 . 3 (syst.) events.
Supplementary Figure Legend from Highly Active Combination of BRD4 Antagonist and Histone Deacetylase Inhibitor against Human Acute Myelogenous Leukemia Cells (2023)

&lt;p&gt;PDF - 95K, Figure legends for the Supplemental Data.&lt;/p&gt;
Catalytic Reduction in Organic Synthesis. Band 1 und 2, Science of Synthesis, Workbench Edition Herausgegeben von J. G. de Vries. (2019)

Thieme, 2018. 992 S., Broschur, 449.00 €.—ISBN 9783132421486
Ambiguous anti‐fouling surfaces: Facile synthesis by light‐mediated radical polymerization (2015)

ABSTRACT In an attempt to create a polymer brush‐based platform for the systematic study for anti‐biofouling surfaces, the benefits of surface initiated, visible light‐mediated radical polymerization are utilized to fabricate well‐defined, chemically ambiguously patterned surfaces. A variety of analytical tools are used to illustrate the precise tuning of surface chemistry and thoroughly characterize spatially well‐defined, hydrophilic/hydrophobic surfaces composed of poly(ethylene glycol methacrylate) and poly(trifluoroethyl methacrylate) with chemical definition on the micron scale. Advantages of both visible light‐mediated photopolymerization and traditional copper‐catalyzed atom transfer radical polymerization are combined to achieve both high spatial control and expanded monomer tolerance. © 2015 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2016, 54, 253–262
ChemInform Abstract: METHODS FOR THE CONVERSION OF ISOXAZOLINES TO β‐HYDROXY KETONES (1982)

Abstract Aus den Isoxazolinen (II) entstehen nach katalytischer Hydrierung die Hydroxy‐ketone (I), die auch aus (II) über eine Ozonolyse unter Annahme der Zwischenstufen (III) und (IV) erhalten werden.
ViNNPruner: Visual Interactive Pruning for Deep Learning (2022)

Neural networks grow vastly in size to tackle more sophisticated tasks. In many cases, such large networks are not deployable on particular hardware and need to be reduced in size. Pruning techniques help to shrink deep neural networks to smaller sizes by only decreasing their performance as little as possible. However, such pruning algorithms are often hard to understand by applying them and do not include domain knowledge which can potentially be bad for user goals. We propose ViNNPruner, a visual interactive pruning application that implements state-of-the-art pruning algorithms and the option for users to do manual pruning based on their knowledge. We show how the application facilitates gaining insights into automatic pruning algorithms and semi-automatically pruning oversized networks to make them more efficient using interactive visualizations.
Experience Using Managed Pressure Cementing Techniques with Riserless Mud Recovery and Controlled Mud Level in the Barents Sea (2018)

Abstract The Barents Sea offers unique drilling challenges related to issues such as biogenetic gas in shallow formations, thermogenic gas seeps up to the seabed from underlying formations, shallow formations with abnormal pressure, shallow reservoirs, low-fracture-pressure formations in part of the overburden, and naturally fractured/karstified carbonate reservoirs. This paper discusses cementing challenges when drilling wells in the Barents Sea and the experience gained using managed pressure cementing (MPC) practices. When drilling the surface hole in potentially slightly overpressured formations, the riserless mud recovery (RMR) technique was used. For the first time on the Norwegian Continental Shelf (NCS), MPC was used when cementing the surface casing. RMR compensates for drilling the overpressurized zones without a riser and blowout preventer (BOP), and MPC allows for pressurization and monitoring of the pressure on the subsea wellhead toward the formation during the cement curing stage. Once the marine riser and BOP were installed, controlled mud level (CML) technology was used during drilling, running casing/liners, cementing operations, and other activities. CML enables manipulation of the fluid level in the riser and therefore helps optimize downhole pressure to avoid losses and maintain an overbalance. CML has proven to be particularly useful during cementing of liners in naturally fractured reservoirs and during setting of balanced cement plugs in an open hole. As a result, high circulation rates can be achieved and conventional high-density cement slurries can be used. MPC using either RMR or CML was employed for the first time in the Barents Sea. Examples of how cementing operations were planned and executed are described and results are presented.
Formation of N-Heterocyclic Carbene–Boryl Radicals through Electrochemical and Photochemical Cleavage of the B–S bond in N-Heterocyclic Carbene–Boryl Sulfides (2013)

The B-S bond in N-heterocyclic carbene (NHC)-boryl sulfides can be cleaved homolytically to NHC-boryl or NHC-thioboryl and thiyl radicals using light, either directly around 300 nm or with a sensitizer at a longer wavelength (>340 nm). In contrast, the electrochemical reductive cleavage of the B-S bond is difficult. This easy photolytic cleavage makes the NHC-boryl sulfides good type I photopolymerization initiators for the polymerization of acrylates under air.
An 82‐in. ultra‐definition 120‐Hz LCD TV using new driving scheme and advanced Super PVA technology (2009)

An ultra‐definition (UD or 3840 × 2160) resolution 82‐in. product with 120‐Hz high‐frame‐rate driving has been developed for LCD‐TV applications. The resolution increase from full HD to UD greatly reduces the available charging time. This problem has been overcome by employing a half‐gate two‐data‐line design (hG‐2D) for Super PVA pixels. Additionally, cost‐effective single‐bank driving has been achieved by adopting a vertical‐quarter‐partitioned (VQP) driving scheme. A viewing angle of 180°, contrast ratio of 2200:1, and brightness of 550 nits have been achieved while maintaining all of the other advantages of the Super‐PVA structure.
Identification of colloidal manganese(IV) in permanganate oscillating reactions (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIdentification of colloidal manganese(IV) in permanganate oscillating reactionsChristopher J. Doona and Friedemann W. SchneiderCite this: J. Am. Chem. Soc. 1993, 115, 21, 9683–9686Publication Date (Print):October 1, 1993Publication History Published online1 May 2002Published inissue 1 October 1993https://pubs.acs.org/doi/10.1021/ja00074a038https://doi.org/10.1021/ja00074a038research-articleACS PublicationsRequest reuse permissionsArticle Views180Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Mechanical and Optical Properties of Polyamide 6/Clay Nanocomposite Cast Films: Influence of the Degree of Exfoliation (2011)

Abstract PA6 nanocomposite films with different nanoclay dispersion degrees are prepared by melt compounding and cast extrusion. The dispersion of the MMT platelets (homogeneity and degree of exfoliation) is evaluated qualitatively by TEM and quantitatively by rheology and NMR; it ranges from microcomposites to highly exfoliated nanocomposites. Compared to neat PA6, the optical properties (clarity, gloss, haze) are worse for the microcomposites and better for the nanocomposites. The mechanical properties depend strongly on the exfoliation level. Better exfoliation leads to higher stiffness. The strain at break decreases compared to neat PA6 films even in the case of highly exfoliated nanocomposites films. At low MMT content, the microcomposite has a higher ductility than well exfoliated nanocomposites films. magnified image
A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats (2010)

Tissue macrophage inflammatory pathways contribute to obesity-associated insulin resistance. Here, we have examined the efficacy and mechanisms of action of a novel anti-inflammatory compound (HE3286) in vitro and in vivo. In primary murine macrophages, HE3286 attenuates LPS- and TNFalpha-stimulated inflammation. In Zucker diabetic fatty rats, inflammatory cytokine/chemokine expression was downregulated in liver and adipose tissue by HE3286 treatment, as was macrophage infiltration into adipose tissue. In line with reduced inflammation, HE3286 treatment normalized fasting and fed glucose levels, improved glucose tolerance, and enhanced skeletal muscle and liver insulin sensitivity, as assessed by hyperinsulinemic euglycemic clamp studies. In phase 2 clinical trials, HE3286 treatment led to an enhancement in insulin sensitivity in humans. Gluconeogenic capacity was also reduced by HE3286 treatment, as evidenced by a reduced glycemic response during pyruvate tolerance tests and decreased basal hepatic glucose production (HGP) rates. Since serum levels of gluconeogenic substrates were decreased by HE3286, it indicates that the reduction of both intrinsic gluconeogenic capacity and substrate availability contributes to the decrease in HGP. Lipidomic analysis revealed that HE3286 treatment reduced liver cholesterol and triglyceride content, leading to a feedback elevation of LDL receptor and HMG-CoA reductase expression. Accordingly, HE3286 treatment markedly decreased total serum cholesterol. In conclusion, HE3286 is a novel anti-inflammatory compound, which displays both glucose-lowering and cholesterol-lowering effects.
Robust environment mapping using flux skeletons (2015)

We consider how to directly extract a road map (also known as a topological representation) of an initially-unknown 2-dimensional environment via an on-line procedure which robustly computes a retraction of its boundaries. While such approaches are well known for their theoretical elegance, computing such representations in practice is complicated when the data is sparse and noisy. In this paper we present the online construction of a topological map and the implementation of a control law for guiding the robot to the nearest unexplored area. The proposed method operates by allowing the robot to localize itself on a partially constructed map, calculate a path to unexplored parts of the environment (frontiers), compute a robust terminating condition when the robot has fully explored the environment, and achieve loop closure detection. The proposed algorithm results in smooth safe paths for the robot's navigation needs. The presented approach is an any-time-algorithm which allows for the active creation of topological maps from laser-scan data, as it is being acquired. The resulting map is stable under variations to noise and the initial conditions. The key idea is the use of a flux-based skeletonization algorithm on the latest occupancy grid map. We also propose a navigation strategy based on a heuristic where the robot is directed towards nodes in the topological map that open to empty space. The method is evaluated on both synthetic data and in the context of active exploration using a Turtlebot 2. Our results demonstrate complete mapping of different environments with smooth topological abstraction without spurious edges.
Design and calibration of a microfabricated floating-element shear-stress sensor (1988)

A microfabricated floating-element shear-stress sensor for measurements in turbulent boundary-layers is reported. Using surface micromachining of polyimide, a 500- mu m*500- mu m probe has been fabricated incorporating a differential-capacitor readout circuit. A model for the sensor response is described and is used for the design of an element to measure shear stresses of 1 Pa in air. The sensor is packaged for calibration in laminar flow, and electrical results obtained match the expected response.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Photoinduced phase transition ofRbMnFe(CN)6studied by x-ray-absorption fine structure spectroscopy (2002)

Photoinduced magnetic phase transition of $\mathrm{RbMnFe}(\mathrm{CN}{)}_{6}$ has been investigated by means of x-ray-absorption fine structure spectroscopy. Upon visible-light (532 nm) irradiation at 30 K, the material undergoes the photoinduced tautomeric spin transition. Mn and Fe K-edge x-ray-absorption near-edge structure spectra have clarified that upon the phase transition, a Fe $3d$ electron is transferred to the Mn $3d$ level; the electronic state of Mn changes from trivalent ${(d}^{4},$ spin momentum $S=2)$ to divalent ${(d}^{5},S=5/2),$ while the Fe state correspondingly varies from divalent ${(d}^{6},S=0)$ to trivalent ${(d}^{5},S=1/2).$ Local structures have been investigated by the extended x-ray-absorption fine-structure analysis for the photoinduced phase as well as for the low- and high-temperature phases. The low-temperature phase shows a significant Jahn-Teller distortion in the Mn(III) octahedron, where the Mn-N distances for four shorter and two longer bonds are 1.964\ifmmode\pm\else\textpm\fi{}0.008 and 2.21\ifmmode\pm\else\textpm\fi{}0.01 \AA{}, respectively. The high-temperature phase gives a longer Mn-N distance of 2.211\ifmmode\pm\else\textpm\fi{}0.006 \AA{}, although some minor contribution from a shorter distance still remains. It is also revealed that the atomic configuration of the -Fe-C-N-Mn- chain is essentially collinear and that the Rb ions locate at the center of the cubic lattice. The photoinduced phase was found to be structurally and electronically identical to the high-temperature phase.