gebhart/patrepeval huggingface dataset:
994: Reduction of the Fibrotic Plaque in a Rat Model of Peyronie's Disease by Long-Term PDE5 Inhibition (2006)

You have accessJournal of UrologyPodium, Monday, May 22, 2006, 3:30 - 5:30 pm1 Apr 2006994: Reduction of the Fibrotic Plaque in a Rat Model of Peyronie's Disease by Long-Term PDE5 Inhibition Monica G. Ferrini, Istvan Kovanecz, Gaby Nolazco, Dolores Vernet, Jacob Rajfer, and Nestor F. Gonzalez-Cadavid Monica G. FerriniMonica G. Ferrini More articles by this author , Istvan KovaneczIstvan Kovanecz More articles by this author , Gaby NolazcoGaby Nolazco More articles by this author , Dolores VernetDolores Vernet More articles by this author , Jacob RajferJacob Rajfer More articles by this author , and Nestor F. Gonzalez-CadavidNestor F. Gonzalez-Cadavid More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)33219-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "994: Reduction of the Fibrotic Plaque in a Rat Model of Peyronie's Disease by Long-Term PDE5 Inhibition." The Journal of Urology, 175(4S), pp. 320–321 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 320-321 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Monica G. Ferrini More articles by this author Istvan Kovanecz More articles by this author Gaby Nolazco More articles by this author Dolores Vernet More articles by this author Jacob Rajfer More articles by this author Nestor F. Gonzalez-Cadavid More articles by this author Expand All Advertisement PDF downloadLoading ...
The evolution of universal adaptations of life is driven by universal properties of matter: energy, entropy, and interaction (2020)

<ns4:p> The evolution of multicellular eukaryotes expresses two sorts of adaptations: local adaptations like fur or feathers, which characterize species in particular environments, and universal adaptations like microbiomes or sexual reproduction, which characterize most multicellulars in any environment. We reason that the mechanisms driving the universal adaptations of multicellulars should themselves be universal, and propose a mechanism based on properties of matter and systems: <ns4:italic>energy</ns4:italic> , <ns4:italic>entropy</ns4:italic> , and <ns4:italic>interaction</ns4:italic> . <ns4:italic>Energy</ns4:italic> from the sun, earth and beyond creates new arrangements and interactions. Metabolic networks channel some of this energy to form cooperating, interactive arrangements. <ns4:italic>Entropy</ns4:italic> , used here as a term for all forces that dismantle ordered structures (rather than as a physical quantity), acts as a selective force. Entropy selects for arrangements that resist it long enough to replicate, and dismantles those that do not. <ns4:italic>Interactions</ns4:italic> , energy-charged and dynamic, restrain entropy and enable survival and propagation of integrated living systems. This fosters <ns4:italic>survival-of-the-fitted</ns4:italic> – those entities that resist entropic destruction – and not only of the fittest – the entities with the greatest reproductive success. The “unit” of evolution is not a discrete entity, such as a gene, individual, or species; what evolves are collections of related interactions at multiple scales. Survival-of-the-fitted explains universal adaptations, including resident microbiomes, sexual reproduction, continuous diversification, programmed turnover, seemingly wasteful phenotypes, altruism, co-evolving environmental niches, and advancing complexity. Indeed survival-of-the-fittest may be a particular case of the survival-of-the-fitted mechanism, promoting local adaptations that express reproductive advantages in addition to resisting entropy. Survival-of-the-fitted accounts for phenomena that have been attributed to neutral evolution: in the face of entropy, there is no neutrality; all variations are challenged by ubiquitous energy and entropy, retaining those that are “fit enough”. We propose experiments to test predictions of the survival-of-the-fitted theory, and discuss implications for the wellbeing of humans and the biosphere. </ns4:p>
Proteoglycans Synthesized by Fetal Guinea Pig Chondrocytes in Culture (1978)

Short term cultures were carried out with chondrocytes and tissue fragments from fetal guinea pig epiphyseal cartilage. Proteoglycans were isolated from these cultures and their properties were compared with those of proteoglycans from adult hyaline cartilage. It was concluded that the proteoglycans synthesized in culture were essentially similar to those present in cartilage matrix in vivo. The authors therefore suggest that fetal guinea pig chondrocytes cultured in monolayer or as aggregates in suspension constitute a useful system for the study of synthesis and secretion of proteoglycans.
The Textile Industry in Southeast Asia, 1400-1800 (1996)

Abstract This study of Southeast Asia's regional and native textile trade highlights the transitional patterns of textile use in sixteenth and seventeenth century Banjarmasin, an important Borneo coast port-polity in that era's international pepper trade. Cloth was a multi-purpose commodity bearing rich indigenous legacy that served as the point of reference for revised political, economic, and cultural transactions. In the new order that was emerging, upstream and downstream regularized their interactions and shared in a common cultural bond that was defined by cloth. This was a locally meaningful response to the changing economic circumstances of the seventeenth century, and was only in part a reaction to an increasingly assertive European presence in the eastern Indonesian archipelago.
Community Detection With Side Information: Exact Recovery Under the Stochastic Block Model (2018)

The community detection problem involves making inferences about node labels in a graph, based on observing the graph edges. This paper studies the effect of additional, nongraphical side information on the phase transition of exact recovery in the binary stochastic block model with <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$n$</tex-math> </inline-formula> nodes. When side information consists of noisy labels with error probability <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\alpha$</tex-math></inline-formula> , it is shown that phase transition is improved if and only if <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$\log (\frac{1-\alpha }{\alpha })=\Omega (\log (n))$</tex-math> </inline-formula> . When side information consists of revealing a fraction <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX"> $1-\epsilon$</tex-math></inline-formula> of the labels, it is shown that phase transition is improved if and only if <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$\log (1/\epsilon)=\Omega (\log (n))$</tex-math></inline-formula> . For a more general side information consisting of <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$K$</tex-math></inline-formula> features, two scenarios are studied, first, <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$K$</tex-math> </inline-formula> is fixed while the likelihood of each feature with respect to corresponding node label evolves with <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$n$</tex-math></inline-formula> , and, second, the number of features <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex-math notation="LaTeX">$K$</tex-math></inline-formula> varies with <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$n$</tex-math></inline-formula> but the likelihood of each feature is fixed. In each case, we find when side information improves the exact recovery phase transition and by how much. In the process of deriving inner bounds, a variation of an efficient algorithm is proposed for community detection with side information that uses a partial recovery algorithm combined with a local improvement procedure.
Vibrational and defect states in SnOx nanoparticles (2006)

We have studied SnOx nanoparticles fabricated by gas-phase condensation and in-flight sintering using Raman and photoluminescence (PL) spectroscopy. We are able to identify various vibrational states of the rutile phase of the SnOx crystal. By thorough analysis of the vibrational modes, we are able to determine the bond lengths of the O–O and Sn–O bonds for the substoichiometric SnO1.5, leading, together with x-ray diffraction data, to a full characterization of the SnO1.5 lattice. In absorption and photoluminescence spectra, we observe a finite density of states inside the band gap due to oxygen vacancies, giving rise to a midgap luminescence peak. Our results suggest that the defect related luminescence efficiency is limited by nonradiative recombination processes and by the oxygen vacancy density. We therefore conclude that the PL intensity has a maximum around a stoichiometry of SnO1.7.
Sodium Extraction from NASICON-Structured Na3MnTi(PO4)3 through Mn(III)/Mn(II) and Mn(IV)/Mn(III) Redox Couples (2016)

Sodium extraction behavior in the rhombohedral Na3MnTi(PO4)3 with the NASICON structure was investigated and shown to have a 0.5 eV separation of the localized-electron Mn3+/Mn2+ and Mn4+/Mn3+ redox energies. Used as a cathode in a sodium-ion half-cell, the redox couples of Mn3+/Mn2+ and Mn4+/Mn3+ exhibit two voltage plateaus located at about 3.6 and 4.1 V vs Na+/Na, respectively. Na3MnTi(PO4)3 also exhibits a small volume change after the extraction of two sodium ions, and the NASICON structure is well-maintained after repeated extraction and insertion of sodium ions.
Phosphorus-31-Nuclear Magnetic Resonance Studies of Murine Candidal Pyelonephritis (1984)

Journal Article Phosphorus-31-Nuclear Magnetic Resonance Studies of Murine Candidal Pyelonephritis Get access J. K. Au-Young, J. K. Au-Young Department of Internal Medicine of the School of Medicine, Department of Medicine of the School of Veterinary Medicine, and the Nuclear Magnetic Resonance Facility, University of California at Davis, Sacramento, California Search for other works by this author on: Oxford Academic PubMed Google Scholar E. Goldstein, E. Goldstein Department of Internal Medicine of the School of Medicine, Department of Medicine of the School of Veterinary Medicine, and the Nuclear Magnetic Resonance Facility, University of California at Davis, Sacramento, California Search for other works by this author on: Oxford Academic PubMed Google Scholar W. E. Lippert, W. E. Lippert Department of Internal Medicine of the School of Medicine, Department of Medicine of the School of Veterinary Medicine, and the Nuclear Magnetic Resonance Facility, University of California at Davis, Sacramento, California Search for other works by this author on: Oxford Academic PubMed Google Scholar R. T. Bogusky, R. T. Bogusky Department of Internal Medicine of the School of Medicine, Department of Medicine of the School of Veterinary Medicine, and the Nuclear Magnetic Resonance Facility, University of California at Davis, Sacramento, California Search for other works by this author on: Oxford Academic PubMed Google Scholar L. D. Cowgill, L. D. Cowgill Department of Internal Medicine of the School of Medicine, Department of Medicine of the School of Veterinary Medicine, and the Nuclear Magnetic Resonance Facility, University of California at Davis, Sacramento, California Search for other works by this author on: Oxford Academic PubMed Google Scholar G. B. Matson G. B. Matson Department of Internal Medicine of the School of Medicine, Department of Medicine of the School of Veterinary Medicine, and the Nuclear Magnetic Resonance Facility, University of California at Davis, Sacramento, California Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 149, Issue 4, April 1984, Pages 648–649, https://doi.org/10.1093/infdis/149.4.648 Published: 01 April 1984
Complementary interpretation of ET(30) polarity parameters of ionic liquids (2020)

Reichardt's empirical ET(30) polarity parameter has been established as appropriate polarity scale for ionic liquids. In this study, the relationships of ET(30) of ionic liquids with the empirical Kamlet-Taft polarity parameters α (hydrogen bond donating ability), β (hydrogen bond accepting ability) and π* (dipolarity/polarizability) as well as Catalán's parameter set SA (solvent acidity), SB (solvent basicity), SP (solvent polarizability) and SdP (solvent dipolarity) are examined by means of multiple square correlation analyses. Several subtasks were carried out to address this main concern. First, the influence of anion structure on ET(30) polarity parameters for various ionic liquids are investigated by use of nine differently substituted pyridinio phenolate betaine dyes of the Reichardt type. It is assumed that halide anions can have an effect on the ET(30) parameter. In the second part, the Kamlet-Taft π* parameters have been independently determined for several protic ionic liquids using 4-tert-butyl-2-(dicyanomethylene)-5-[4-(diethylamino)-benzylidene]-Δ3-thiazoline (Th) and N,N-diethyl-4-nitroaniline (DENA) to show the impact of the hydrogen bond donating ability of the IL on the actual π* values as function of probe. α and SA values have been measured using the dicyano-bis(1,10-phenanthroline) iron(ii) complex (Fe) as HBD probe. Finally, the newly determined Reichardt ET(30), Kamlet-Taft and Catalán parameters of ionic liquids were used in addition to literature data to prove correlations of ET(30) with α and π* as well as of ET(30) with SA and SdP. Linear correlations of SdP with the molar concentration of the ionic liquid are highlighted.
Estradiol-secreting adrenal oncocytoma in a 31-year old male (2022)

Oncocytic adrenocortical tumors (OAT) are rare and often are non-functional. We report a unique case of an estradiol-secreting adrenal oncocytoma in a 31-year-old male discovered upon an infertility and gynecomastia work-up. After resection of the 9 cm adrenal mass, the patient's estradiol levels normalized from 83.2 pg/ml to 19.0 pg/ml. Gonadotropins and serum dehydroepiandrosterone sulfate also normalized.
Adiabatic pulses enhance surface nuclear magnetic resonance measurement and survey speed for groundwater investigations (2016)

ABSTRACT Surface nuclear magnetic resonance (surface NMR) is an extremely powerful tool for groundwater resource investigations. However, the technique suffers from an inherently low signal-to-noise ratio (S/N), which commonly necessitates extensive signal averaging, resulting in very long measurement times. Previous approaches to improve S/N and measurement efficiency have focused primarily on reducing noise, through hardware and processing advancements. We introduce a new and divergent approach to actually increase the signal amplitude by modifying the form of the transmitted pulse used to excite the groundwater signals. An on-resonance pulse, the only form of excitation pulse previously used in surface NMR, has a fixed frequency and induces coherent excitation over a narrow range of transmit field strengths. Given spatially inhomogeneous fields underlying the surface coil, an on-resonance pulse excites water, a limited volume of water, producing a similarly limited signal amplitude. An adiabatic pulse, one of many pulse forms used for medical imaging and chemical spectroscopy, modulates pulse frequency and provides excitation over a much larger range of transmit field amplitudes. Numerical simulations of surface NMR with adiabatic pulses demonstrate almost a factor of three improvement in the peak signal amplitude compared to an on-resonance pulse. Simulations also show that a single measurement using an adiabatic pulse with high transmit current provides sensitivity to water over a wide range of depth. In contrast, multiple on-resonance measurements using a range of transmit currents are required to span sensitivity over a similar range of depths. Numerical simulation results are validated by the first field experiments comparing on-resonance and adiabatic pulses. We have considered how improvements in S/N can be used for dramatically improved measurement speed and how other advantages of adiabatic pulses may more generally be used to enhance surface NMR measurements.
Development of rear pre-crash safety system for rear-end collisions (2007)

Pre-crash safety systems using radar detecting technology have been commercialized in the market. While the primary focus of these systems have been for frontal collisions, rear-end collisions actually have a higher proportion of the traffic accident injuries in Japan. In this paper, a new pre-crash safety system for rear-end collisions is explained. It was developed to help alert drivers of vehicles approaching from behind, and also to reduce whiplash injury. This new system uses a millimeter-wave radar installed in the rear bumper to detect a vehicle approaching closely from behind. If it judged that there is high risk of collision, the hazard lights would flash to warn the driver of the approaching vehicle and the headrests are automatically moved forward. Sensors in the headrests detect the location of the occupants’ head and shifts the headrests to a closer position to the head before the collision occurs, thereby reducing the risk of whiplash injury. This paper shows the effectiveness of the pre-crash hazard light and pre-crash headrest technology.
Prediction of path loss in environments with high-raised buildings (2002)

The purpose of this paper is to investigate the accuracy of path loss estimation of the propagation from roof-top level to street level. From the analysis, based on measurements, it is found that a single diffraction screen combined with a reflection screen utilizing the height information reduces the standard deviation of the prediction error by 2.4 dB for 90% of the investigated heights.
Public Switched Telephone Network (2007)

This chapter contains sections titled: Introduction PSTN Transport Mechanisms Switching and Synchronization Signaling Systems Network Performance and Management Conclusion Glossary Cross References References Web Sites
ROLLOVER CAUSED BY CONCRETE SAFETY SHAPED BARRIER, VOLUME I - TECHNICAL REPORT. FINAL REPORT (1989)

The objectives of this study are to: (1) identify the root causes of rollover of vehicles in impacts with concrete safety shaped barriers, (2) determine the extent and severity of overturn collisions with concrete safety shaped barriers, and (3) identify potential countermeasures to reduce shaped concrete barrier rollovers. The study approach consisted of critical review of literature, statistical and clinical analysis of four accident data files, and computer simulations. The extent of the rollover problem on concrete safety shaped barriers is found to be less than reported in previous literature. A number of impact conditions were identified from accident studies and confirmed by simulation as potential contributory factors to rollovers. Three alternate shapes were evaluated as potential countermeasures: (1) F-shape, (2) single constant sloped barrier, and (3) vertical wall. Results of the evaluation show that the F-shape barrier offers little performance improvement. The vertical wall barrier offers the greatest reduction in rollover potential, but also with the greatest increase in lateral accelerations. The single constant sloped barrier with an 80 degree slope may provide the best compromise solution. A benefit/cost analysis is needed and recommedned to properly compare between the various barrier shapes. This is Volume I of a two-volume final report. The other volume, FHWA-RD-88-220, contains appendixes that are too bulky for inclusion in this technical report. It is only available from the National Technical Information Service.
A 15/spl times/15 mm, 1 /spl mu/A, reliable sensor-net module: enabling application-specific nodes (2006)

An ultra-small, low-power sensor-net module called ZN1 is developed. ZN1 integrates MCU, ZigBee RF into an ultra-small 15times15-mm module with an ultra-low standby current less than 1 muA. The and highly reliable operation for more than 15 years of the ZN1 enable low-cost practical application-specific sensor nodes for HVAC, structure monitoring, office management, security, medicine, and healthcare. We describe architecture and technologies for developing the ZN1 module. Moreover, we demonstrate two applications that we developed simultaneously: food sanitation and home healthcare. We also show results of the ZN1 module evaluation and discuss reliability of the ZN1
Discrete Triangular Tripalladium Sandwich Complexes of Arenes (2007)

Sandwich triangles: A bis([2.2]paracyclophane)tripalladium complex (1) was isolated and characterized by NMR spectroscopy, and a mixed-ligand derivative was structurally characterized. These complexes are the first isolated μ3-arene trimetal complexes of a Group 10 metal. Complex 1 undergoes facile release of a Pd0 atom (see scheme) and as such may be regarded as a Pd0 reservoir.
Optimization of conductive fluids for liquid metals in THz devices (2017)

We characterize the THz properties of liquid metals in conductive fluids. These results will inform the design of future reconfigurable THz signal processing components based on liquid metals incorporated into waveguides.
An Experimental Investigation of the Patterns of International Trade (2013)

AbstractThis paper studies a laboratory economy with some of the prominent features of an international economic system. The patterns of trade and output predicted by the law of comparative advantage are observed evolving within the experimental markets. Market prices and quantities move in the direction of the competitive equilibrium, but the quantitative predictions of the (risk-neutral) competitive equilibrium are rejected. Considerable amounts of economic activity occur as disequilibria. Factor-price equalization is observed, but there is a universal tendency for factors of production to trade at prices below their marginal products.
Status of the Fermilab electron cooling project (1999)

The first stage of the Fermilab Electron Cooling R&D program is now complete: technology necessary to generate hundreds of milliamps of electron beam current at MeV energies has been demonstrated. Conceptual design studies show that with an electron beam current of 200 mA and with a cooling section of 20 m electron cooling in the Fermilab Recycler ring can provide antiproton stacking rates suitable for the Tevatron upgrades beyond Run II luminosity goals. A prototype of such an electron cooling system is now being built at Fermilab as part of the continuing R&D program. This paper describes the electron cooling system design as well as the status of the Fermilab electron cooling R&D program.