gebhart/patrepeval huggingface dataset:
QUALITY ASSESSMENT OF EFFECTIVENESS OF SAFETY MONITORING BASED ON ON-SITE VISUALIZATION USING NEW DEVICES WITH VARIOUS COST RANGES (2015)

OSV (On-Site Visualization) monitoring is a system that measures information which is shared visually in real time at site. It was introduced by Akutagawa in 2006 and has been effectively applied at various construction sites since then. The basic function of the OSV is to show changes in deformation, pressure, inclination, etc. of structures as well as ground movement using colored lights, namely blue, yellow and red through light-emitting converter and LED lights electrically. Through these previous site experiences, the OSV performance has been reassessed; it has been recognized that a major problem with the system is the cost of the number of electrically driven OSV devices needed to cover many locations for a more effective OSV operation. More simple mechanical monitoring devices have now been devised which do not require electricity and are sufficient and reliable enough to monitor structure and ground movement. These low-cost OSV devices have been introduced at the Bai Chay Road project in Vietnam as the first trial of low-cost OSV on an overseas project. Finally we propose a basic strategy for evaluating the performance of the OSV system and improving construction safety, utilizing low-cost OSV.
Wavelength-tunable semiconductor laser with a liquid crystal pixel mirror (2002)

Tunable semiconductor lasers are compact, versatile sources used extensively in dense-wavelength-division-multiplexing (DWDM) optical communication systems, precision metrology, environmental monitoring, and laser spectroscopy. We have developed a twisted nematic liquid crystal device, the liquid crystal pixel mirror (LCPM), successfully as electronically tunable spectral filters for wavelength selection in external cavity semiconductor lasers. In this talk, we report recent advances in this class of electronically tunable single- and multiple-wavelength semiconductor lasers at 650 and 830 nm. Preliminary results of operating the laser at 1.5 microns will also be shown. The laser output can be locked to the ITU grid at 100 GHz intervals. Output power of the laser is as high as several hundred milliwatts, with a tuning range of several tens of nanometers. The laser can be operated either in the continuous-wave (CW) or mode-locked configuration. The linewidth of the laser in the free-running CW mode is about 30 MHz. Fine-tuning of the cw output wavelength can be achieved by changing the driving voltage to the desired pixels of the LCPM. In the mode-locked configuration, the laser design allows intra-cavity dispersion compensation and pulse compression.
Spectral Karyotyping (2003)

Historically in clinical cytogenetics, G-banding has been the gold standard for detecting gross chromosomal abnormalities, ranging from simple numerical changes to the identification of complex structural rearrangements in clinical samples. The designation “marker chromosome” or “derivative chromosome” has been used to indicate that G-banding has been unable to provide a definitive identification of the aberration. This is often because the complexity of the rearrangement has resulted in the lack of a coherent and recognizable banding pattern. The advent of the various multicolor fluorescence in situ hybridization (FISH) chromosomal painting techniques (1,1) has greatly improved our ability to identify all marker chromosomes, but these techniques still need some careful planning in rapidly achieving the goal of identifying complex chromosomal rearrangements.
DLVO AND NON-DLVO SURFACE FORCES AND INTERACTIONS IN COLLOIDAL DISPERSIONS (1997)

Abstract Some aspects of DLVO and non-DLVO forces in colloidal systems are over-viewed. The influence of long range interactions on some kinetic properties of dispersions, as Brownian diffusion, is discussed. It is shown, both theoretically and experimentally, that the electrostatic repulsion increases the collective diffusivity. The film stratification and oscillatory structure forces in colloidal suspensions are considered within the framework of an uniform approach The presence of small colloidal species (e. g. micelles or polymer molecules) may lead to several maxima and minima in the disjoining pressure isotherm. The particular case of interacting emulsion droplets is examined accounting for the interfacial deformability. The droplet deformation acts as a soft repulsion but affects also the remaining contributions to the interaction energy due to changes of the droplet shape. A general procedure for calculating the inter-droplet interaction energy, as well as the equilibrium film radius and thickness in a doublet of droplets, is suggested. The energy of interaction between charged colloidal particles, due to correlations of the density fluctuations in the electric double layer is also studied. It is found that this effect may lead to attraction greater than the van der Waals contribution, especially when multivale counter ions are present.
Voltage-controlled oscillator in the coil (2006)

In this paper we have examined the effect of devices inside an inductor through simulations and measurements. A voltage-controlled oscillator (VCO) was constructed inside an inductor using layout techniques that minimize eddy current loss and magnetic coupling. Measurement results show that this compact VCO has an equal performance in phase noise and output power as compared to a traditional VCO while reducing the area by about 50%.
Transgenic plants exhibiting enhanced phytochelatin-based heavy metal tolerance and methods of use thereof (2023)

Transgenic plants exhibiting phytochelatin-based heavy metal tolerance and methods of use thereof for bioremediation are disclosed.
Giant nonlinearity arising from the vertical split ring resonators (Conference Presentation) (2017)

Increasing the nonlinear optical response at nanometer length scale is a very important issue due to the wide applications in various disciplines such as information science, bio-medicine and quantum computation technology. Second harmonic generation (SHG) arising from the metal nanostructures has provide a very powerful tool in studying the surface and interface properties of these materials. The SHG from various kinds of asymmetric geometric configurations such as V and L shape structures, imperfect nano-spheres, metal/insulator/metal multilayer structures, and planar split ring resonators have been proposed. However, all the previous studies in plasmonic nonlinear optical behavior rely on the enhancement of the electric field and seldom considered the magnetic field effect. In this work, we present a vertical split ring resonator (SRR) based metamaterial to generate SHG. By adopting such a novel structure, both the electric and magnetic field will be significantly enhanced due to the localized surface plasmon resonance, hence the generation of the second-harmonic and its re-emission into the far field are dramatically increased several orders comparing with that of the planar SRR. We simulated and fabricated the reflective type vertical SRR, and optimized the aspect ratio to maximize the SHG signal. We further systematically studied the nonlinear optical response in the vertical SRR dimers and trimers and found that the gap distance between two SRRs plays a very important role in the SHG intensity. This work paves a new way in increasing the nonlinear transition quantum efficiency and provides a new insight in designing new nonlinear sources.
Novel Approach for Gesture Recognition Using mmWave FMCW RADAR (2022)

Hand gesture recognition driven by RADAR technology has attracted significant attention in recent years. Among various RADAR types, frequency-modulated continuous-wave (FMCW) RADAR is used in this work due to its very high range and velocity resolution. However, data collected by RADAR are disturbed by static background and static clutter. Therefore, a novel data preprocessing approach is proposed to remove the static background and clutter in the acquired data. A convolutional neural network is used to extract the features of the acquired data set. To the best of our knowledge, this is the first time that range, velocity and angle features are combined in one map, forming the input signal of a convolutional neural network. Classifiers are applied to recognize gestures. Experimental results show that the proposed method using the XGBoost classifier can achieve a high recognition accuracy of 98.93% on the test set. In contrast, the proposed method with the random forest classifier can achieve a recognition rate of 100% on the same test set with six dynamic hand gestures. This approach could be useful in aspects such as in-car entertainment systems and smart homes.
1665: Practice Patterns of Ureteral Stenting following Routine Ureteroscopic Stone Surgery: A Survey of Practicing Urologists (2006)

You have accessJournal of UrologyPodium, Wednesday, May 24, 2006, 1:00 - 3:00 pm1 Apr 20061665: Practice Patterns of Ureteral Stenting following Routine Ureteroscopic Stone Surgery: A Survey of Practicing Urologists Brian K. Auge, Jamey A. Sarvis, and Glenn M. Preminger Brian K. AugeBrian K. Auge More articles by this author , Jamey A. SarvisJamey A. Sarvis More articles by this author , and Glenn M. PremingerGlenn M. Preminger More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)33857-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1665: Practice Patterns of Ureteral Stenting following Routine Ureteroscopic Stone Surgery: A Survey of Practicing Urologists." The Journal of Urology, 175(4S), p. 537 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 537 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Brian K. Auge More articles by this author Jamey A. Sarvis More articles by this author Glenn M. Preminger More articles by this author Expand All Advertisement PDF downloadLoading ...
A Low-Power Process-Scalable Super-Heterodyne Receiver With Integrated High-$Q$ Filters (2011)

A super-heterodyne receiver utilizing integrated high-Q filters to condition the desired signal to be digitized by a bandpass ADC at an IF of 110 MHz achieves a NF of 2.8 dB and an IIP3 of -8.4 dBm. The conventional M-phase filter is developed to a new form of high-Q filter that is centered at sum or difference of two clocks. The M-phase filter is also evolved to take two quadrature inputs to perform image rejection, while exhibiting a high-Q bandpass response with desired signal located in the center. Built of inverters, switches, and MOS capacitors, the receiver follows technology scaling and is reconfigurable through a clock. The receiver including the dividers and LO path draws 12 mA of battery current and occupies 0.76 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> in 65-nm CMOS.
Investigation of High-Efficiency Parallel-Circuit Class-EF Power Amplifiers With Arbitrary Duty Cycles (2020)

In this article, a parallel-circuit class-EF power amplifier with a shunt quarter-wave transmission-line for driving signals with arbitrary duty cycles is proposed and investigated. At the particular condition of duty cycle = 1/3, the values of the elements in the output network, as well as, some critical design parameters are analyzed and optimized. This leads to a series of significant improvements in the peak drain voltage (Vmax), the maximum operating frequency (fmax), and the power output capability (cp). Furthermore, in order to verify the advantage of the proposed new amplifier and its feasibility in realistic situations, a proof-of-concept circuit is designed and fabricated. Finally, at the operating frequency of 3.59 GHz, excellent performance has been achieved with the power-added efficiency of 79.9% and output power of 40.7 dBm.
The Selective Degradation of Synaptic Connexin 43 Protein by Hypoxia-induced Autophagy Impairs Natural Killer Cell-mediated Tumor Cell Killing (2015)

Although natural killer (NK) cells play an important role in the control of melanoma, hypoxic stress in the tumor microenvironment may impair NK-mediated tumor cell killing by mechanisms that are not fully understood. In this study, we investigated the effect of hypoxia on the expression and channel activity of connexin 43 (Cx43) in melanoma cells and its impact on their susceptibility to NK cell-mediated lysis. Our results demonstrated that hypoxic stress increases Cx43 expression in melanoma cells via hypoxia-inducible factor-1α (HIF-1α) transcriptional activity. Hypoxic cells displaying increased Cx43 expression were less susceptible to NK cell-mediated lysis compared with normoxic cells expressing a moderate level of Cx43. Conversely, when overexpressed in normoxic tumor cells, Cx43 improves their susceptibility to N cell-mediated killing. We show that the NK cell immune synapse formed with normoxic melanoma cells is more stable and contains a high level of gap-junctional Cx43 whereas that formed with hypoxic cells is less stable and contains a significant lower level of gap-junctional Cx43. We provide evidence that the activation of autophagy in hypoxic melanoma cells selectively degrades gap-junctional Cx43, leading to the destabilization of the immune synapse and the impairment of NK cell-mediated killing. Inhibition of autophagy by genetic or pharmacological approaches as well as expression of the non-degradable form of Cx43 significantly restore its accumulation at the immune synapse and improves N cell-mediated lysis of hypoxic melanoma cells. This study provides the first evidence that the hypoxic microenvironment negatively affects the immune surveillance of tumors by NK cells through the modulation of Cx43-mediated intercellular communications.
COVID-19 Convalescent Plasma for the Treatment of Immunocompromised Patients: A Systematic Review and Meta-analysis (2023)

These findings suggest that transfusion of COVID-19 convalescent plasma is associated with mortality benefit for patients who are immunocompromised and have COVID-19.
The role of adjuvants in overcoming antibacterial resistance due to enzymatic drug modification (2022)

Enzymatic drug deactivation is an important contributor to bacterial resistance. Adjuvants which inhibit the β-lactamases help maintain the efficacy of the β-lactams, demonstrating the potential for this strategy for other antibacterial classes.
Volterra-based Nonlinear Compensation in 400 Gb/s WDM Multiband Coherent Optical OFDM Systems (2014)

We apply a 3rd-order inverse Volterra series nonlinear equalizer to a 400 Gb/s WDM multiband PM-16QAM OFDM signal. IVSTF-NLE provides a 0.6 dB Q-factor improvement and 1 dB nonlinear threshold increase compared to linear equalization.
Strain-specific steroidal control of pituitary function (2007)

We have previously shown that 7B2 null mice on the 129/SvEvTac (129) genetic background die at 5 weeks of age with hypercorticosteronemia due to a Cushing's-like disease unless they are rescued by adrenalectomy; however, 7B2 nulls on the C57BL/6NTac (B6) background remain healthy, with normal steroid levels. Since background exerts such a profound influence on the phenotype of this mutation, we have evaluated whether these two different mouse strains respond differently to high circulating steroids by chronically treating wild-type 129 and B6 mice with the synthetic steroid dexamethasone (Dex). Dex treatment decreased the dopamine content of the neurointermediate lobes (NIL) of 129 mice, leading to NIL enlargement and increased total D(2)R mRNA in the 129, but not the B6, NIL. Despite the decrease in this inhibitory transmitter, Dex-treated 129 mice exhibited reduced circulating alpha-melanocyte-stimulating hormone (alpha-MSH) along with reduced POMC-derived peptides compared with controls, possibly due to reduced POMC content in the NIL. In contrast, Dex-treated B6 mice showed lowered cellular ACTH, unchanged alpha-MSH and beta-endorphin, and increased circulating alpha-MSH, most likely due to increased cleavage of NIL ACTH by increased PC2. Dex-treated 129 mice exhibited hyperinsulinemia and lowered blood glucose, whereas Dex-treated B6 mice showed slightly increased glucose levels despite their considerably increased insulin levels. Taken together, our results suggest that the endocrinological response of 129 mice to chronic Dex treatment is very different from that of B6 mice. These strain-dependent differences in steroid sensitivity must be taken into account when comparing different lines of transgenic or knockout mice.
Application of dynamic optical tomography for the detection of a multi-phase physiologic response to Valsalva maneuver in healthy breast tissue (2004)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text R. E. Hardin, D. P. Klemer, M. S. Katz, N. A. Franco, H. L. Graber, C. H. Schmitz, R. L. Barbour, A. G. Smeraldi, and T. F. Panetta, "Application of dynamic optical tomography for the detection of a multi-phase physiologic response to Valsalva maneuver in healthy breast tissue," in Biomedical Topical Meeting, OSA Technical Digest (Optica Publishing Group, 2004), paper ThF37. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Machine Learned Prediction of Reaction Template Applicability for Data-Driven Retrosynthetic Predictions of Energetic Materials (2020)

State of the art computer-aided synthesis planning models are naturally biased toward commonly reported chemical reactions, thus reducing the usefulness of those models for the unusual chemistry relevant to shock physics. To address this problem, a neural network was trained to recognize reaction template applicability for small organic molecules to supplement the rare reaction examples of relevance to energetic materials. The training data for the neural network was generated by brute force determination of template subgraph matching for product molecules from a database of reactions in U.S. patent literature. This data generation strategy successfully augmented the information about template applicability for rare reaction mechanisms in the reaction database. The increased ability to recognize rare reaction templates was demonstrated for reaction templates of interest for energetic material synthesis such as heterocycle ring formation.The following article has been submitted to by the 21st Biennial APS Conference on Shock Compression of Condensed Matter. After it is published, it will be found at https://publishing.aip.org/resources/librarians/products/journals/.
OTX2 non-cell autonomous activity regulates inner retinal function (2020)

Abstract OTX2 is a homeoprotein transcription factor expressed in photoreceptors and bipolar cells in the retina. OTX2, like many other homeoproteins, transfers between cells and exerts non-cell autonomous effects such as promoting survival of retinal ganglion cells that do not express the protein. Here we used a genetic approach to target extracellular OTX2 in the retina by conditional expression of a secreted single chain anti-OTX2 antibody. Compared to control mice, the expression of this antibody by Parvalbumin-expressing neurons in the retina is followed by a reduction in visual acuity in one-month-old mice with no alteration of the retinal structure or cell type number or aspect. A- and b-waves measured by electroretinogram were also indistinguishable from control mice, suggesting no functional deficit of photoreceptors and bipolar cells. Mice expressing the OTX2-neutralizing antibody did show a significant doubling in the flicker amplitude, consistent with a change in inner retinal function. Our results show that interfering in vivo with OTX2 non-cell autonomous activity in the postnatal retina leads to an alteration in inner retinal cell functions and causes a deficit in visual acuity. Significance statement OTX2 is a homeoprotein transcription factor expressed in retinal photoreceptors and bipolar cells. Although the Otx2 locus is silent in the inner retina, the protein is detected in cells of the ganglion cell layer consistent with the ability of this class of proteins to transfer between cells. We expressed a secreted single chain antibody (scFv) against OTX2 in the retina to neutralize extracellular OTX2. Antibody expression leads to reduced visual acuity with no change in retinal structure, or photoreceptor or bipolar physiology; however, activity in the inner retina was altered. Thus, interfering with OTX2 non-cell autonomous activity in postnatal retina alters inner retinal function and causes vision loss, highlighting the physiological value of homeoprotein direct non-cell autonomous signaling.
Display-Special Contribution from IDW '98. Reflective-type polymer dispersed LC-mode Projection Display. (1999)

A new compact projection display has been developed using light valves based on a 2-inch diagonal low-temperature poly-Si TFT reflective XGA array and polymer dispersed LC-mode, 120-W ultrahigh-pressure short-arc lamp (UHP lamp), and simple optical components. Luminous flux of 1400 ANSI-lm, contrast ratio of 85, and the illuminance homogeneity of 90% were achieved. Simulation by basic optical theory in concentrators and experiments with a simplified reflective-type polymer dispersed LC-mode light valve indicates that the performance could be improved in future up to a luminous flux of 1600 ANSI-lm with contrast ratio of more than 150.
Les nanotechnologies pour la conception de nouveaux médicaments (2012)

The use of nanotechnologies for the targeted delivery of therapeutic agents is a research strategy which can lead to more efficacious drugs fulfilling unmet medical needs. The morphology, supramolecular organization and properties of first, second and third generation nanocarriers used for the targeted delivery of drugs are discussed. These different nanocarriers (liposomes, nanoparticles, polymers, etc.) may: (I) protect the drug from degradation by the biological environment; (II) allow the controlled delivery of the active molecule by an external stimulus; (III) avoid the recognition of the drug by the reticulo-endothelial system; (IV) overcome multidrug resistance mechanisms of cancer cells and finally (V) very specifically target the therapeutic agent to the diseased cell by means of selective ligands. Some therapeutic applications of these different types of nanocarriers are discussed, especially in the field of cancer therapy. Finally, the future challenges and perspectives of nanotechnologies, especially for "theragnostic" and gene therapy are briefly discussed.
Gain-assisted critical coupling for high-performance coherent perfect absorbers (2015)

Balanced radiation and absorption rates of an optical resonator are necessary for coherent perfect light absorption in many active device applications. This balance is referred to as critical coupling condition. We propose a gain-assisted method for exact access to critical coupling conditions without altering any structure parameters. In a coherent absorber with additional internal gain media, critical coupling with arbitrarily high coherent signal extinction can be obtained by continuously tuning optical pumping density. Assuming a surface-plasmon resonance grating covered by a gain layer as a promising architecture, we numerically demonstrate gain-assisted continuous access to its critical coupling point with experimentally probable settings. In addition, the gain tuning further introduces switching of the coherent-absorber's functionality to a conventional lossless beam splitter.
Supplementary Figure Legend from Global Evaluation of Eph Receptors and Ephrins in Lung Adenocarcinomas Identifies EphA4 as an Inhibitor of Cell Migration and Invasion (2023)

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