gebhart/patrepeval huggingface dataset:
Relation between the Weave Mode in Low Speed Range and Slalom Running of Motorcycles (2012)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;Recently, our research has focused on the weave mode. This is a representative vibration mode of motorcycles and is important when considering maneuverability and stability. In a method of analyzing the weave mode, a disturbance is applied to the handle bars of the motorcycle during running and then the response waveform of the roll angle and other items at that time is used to perform estimations. However, when the motorcycle is driven at low speeds, the steering operations of the rider have a large effect on the running data and this makes estimation difficult. Therefore, it was assumed that weave mode data can be estimated from slalom running data since this possesses almost the same vibration frequency as the weave mode in low speed range.&lt;/div&gt;&lt;div class="htmlview paragraph"&gt;In this research, a simulation was used to investigate the relationship between the weave mode and slalom running. The results of the investigation confirmed that slalom running at a specified speed around pylons placed apart at a specific interval resulted in the same vibration mode as the weave mode in low speed range. Furthermore, the data obtained from actually performing the slalom running was compared to the simulation results, and the same trends in the steering torque and roll angle, which are vital data when considering maneuverability and stability, were confirmed.&lt;/div&gt;&lt;/div&gt;
UMP-PerComp: A Ubiquitous Multiprocessor Network-Based Pipeline Processing Framework for Pervasive Computing Environments (2007)

Pervasive computing provides an attractive vision for the future of computing where contextual intelligent services will be available anywhere at any time. However, how to integrate distributed resources existed among heterogeneous devices to build pervasive applications that can constantly adapt to the highly dynamic computing environment is still a challenge. By analyzing the pipelining feature within a user task and exploiting the parallelism among ubiquitous processors, we propose UMP-PerComp, a ubiquitous multiprocessor-based pipeline processing architecture to support high performance pervasive application development. UMP-PerComp is an integrated comprehensive framework that makes the development of pervasive applications easier. It includes a set of common services such as context management, resource management, service migration, topology management, that help to build applications and directly simplify the task decoupling and service composition. We describe the design and implementation of UMP-PerComp in this paper. Besides, we develop a distributed JPEG encoding application successfully on the UMP-PerComp. Our experience confirms that UMP-PerComp is a flexible, scalable and practicable framework with high performance.
Protein-protein interactions of the p53 family with the Bcl-2 family in hepatocellular carcinoma (2011)

Bcl-2 family proteins serve as critical regulators in apoptosis, either promoting or inhibiting cell death via the mitochondrial apoptosis signaling pathway. Wildtype p53 promotes apoptosis via transcription-dependent and transcription-independent mechanisms. The latter may be mediated by direct translocation of p53 to the mitochondria where it leads to outer mitochondrial membrane permeabilization (OMMP) by forming an inhibitory complex with the anti-apoptotic Bclxl protein.
The Expression of HAK-Type K+ Transporters Is Regulated in Response to Salinity Stress in Common Ice Plant (2002)

Four transcripts homologous to K(+) transporters of the HAK/KT/KUP family have been characterized from the common ice plant (Mesembryanthemum crystallinum). We report tissue-specific expression of McHAK1 and McHAK4 transcripts abundant in roots, leaves, and stems. McHAK2 was predominantly present in stems and McHAK3 in root tissues. By in situ hybridizations, the McHAKs showed signals in the leaf vascular bundles, mesophyll, and epidermal cells as well as in epidermal bladder cells. In mature roots, transcripts were mainly localized to the vasculature, and in differentiated root tips, the strongest signals were obtained from the epidermis. Expression of McHAK1, McHAK2, and McHAK4 complemented a yeast mutant defective in low- and high-affinity K(+) uptake. Growth of the yeast mutant was restored at low-millimolar K(+) concentrations and was inhibited by Rb(+) and Cs(+) but was not affected by Na(+). Transcript levels of McHAK1 and McHAK4 increased by K(+) starvation and by salt stress of 400 mM NaCl in leaves and roots. Expression of McHAK2 and McHAK3 was stimulated in leaves and was transiently induced in roots in response to high salinity with prestress transcript levels restored in salt-adapted plants. We discuss possible roles for such transporters in ion homeostasis at high salinity.
Presteady-state Analysis of Avian Sarcoma Virus Integrase (2002)

Integrase catalyzes insertion of a retroviral genome into the host chromosome. After reverse transcription, integrase binds specifically to the ends of the duplex retroviral DNA, endonucleolytically cleaves two nucleotides from each 3'-end (the processing activity), and inserts these ends into the host DNA (the joining activity) in a concerted manner. In first-turnover experiments with synapsed DNA substrates, we observed a novel splicing activity that resembles an integrase joining reaction but uses unprocessed ends. This splicing reaction showed an initial exponential phase (k(splicing) = 0.02 s(-1)) of product formation and generated products macroscopically indistinguishable from those created by the processing and joining activities, thus bringing into question methods previously used to quantitate these reactions in a time regime where multiple turnovers of the enzyme have occurred. With a presteady-state assay, however, we were able to distinguish between different pathways that led to formation of identical products. Furthermore, the splicing reaction allowed characterization of substrate binding and specificity. Although integrase requires only a 3' hydroxyl with respect to nucleophiles derived from DNA, it specifically favors the cognate sequence CATT as the electrophile. These experimental results support a two-site "switching" model for binding and catalysis of all three integrase activities.
Aqueous Processing for Printed Organic Electronics: Conjugated Polymers with Multistage Cleavable Side Chains (2017)

The ability to process conjugated polymers via aqueous solution is highly advantageous for reducing the costs and environmental hazards of large scale roll-to-roll processing of organic electronics. However, maintaining competitive electronic properties while achieving aqueous solubility is difficult for several reasons: (1) Materials with polar functional groups that provide aqueous solubility can be difficult to purify and characterize, (2) many traditional coupling and polymerization reactions cannot be performed in aqueous solution, and (3) ionic groups, though useful for obtaining aqueous solubility, can lead to a loss of solid-state order, as well as a screening of any applied bias. As an alternative, we report a multistage cleavable side chain method that combines desirable aqueous processing attributes without sacrificing semiconducting capabilities. Through the attachment of cleavable side chains, conjugated polymers have for the first time been synthesized, characterized, and purified in organic solvents, converted to a water-soluble form for aqueous processing, and brought through a final treatment to cleave the polymer side chains and leave behind the desired electronic material as a solvent-resistant film. Specifically, we demonstrate an organic soluble polythiophene that is converted to an aqueous soluble polyelectrolyte via hydrolysis. After blade coating from an aqueous solution, UV irradiation is used to cleave the polymer’s side chains, resulting in a solvent-resistant, electroactive polymer thin film. In application, this process results in aqueous printed materials with utility for solid-state charge transport in organic field effect transistors (OFETs), along with red to colorless electrochromism in ionic media for color changing displays, demonstrating its potential as a universal method for aqueous printing in organic electronics.
The product of the proto-oncogene c-kit (P145c-kit) is a human bone marrow surface antigen of hemopoietic precursor cells which is expressed on a subset of acute non-lymphoblastic leukemic cells. (1991)

A monoclonal antibody (17F11) was raised by immunization of a Balb/c mouse with leukemic blasts from a patient with acute non-lymphocytic leukemia (ANLL). This antibody recognizes most leukemic blasts of myeloid but not of lymphoid lineage and no peripheral blood cells. By screening NIH-3T3 fibroblasts transfected with the human proto-oncogene c-kit (NIH-3T3/hckit) it could be shown that 17F11 specifically recognizes the gene product P145c-kit. Immunofluorescence analysis on normal hemopoietic cells revealed that 17F11 weakly stains 1-3% of bone marrow mononuclear cells (BMMNC). By FACS sorting and colony assays it could be shown that granulocyte--macrophage progenitor cells could be enriched 10-20-fold, granulocyte progenitors 50-80-fold, and erythroid and multipotential progenitor cells 15-20-fold, in the 17F11 positive fraction. Double fluorescence analysis revealed that P145c-kit is co-expressed on 40-60% of the CD34 positive BMMNC. Finally, these data show that P145c-kit is expressed on blast cells from most patients with ANLL (26/30) and chronic myeloid leukemia in blast crisis (7/9), but is absent on blasts from patients with acute lymphoblastic leukemia expressing the T-, B-lineage, or common ALL phenotypes.
POINT-OF-NEED DIAGNOSTICS: BIOSURVEILLANCE WITH A DEVICE2CLOUD CAPABILITY IN SIERRA LEONE (2017)

Background Infectious diseases contribute to a high burden of diseases globally. Surveillance using low-cost technology, combined with cutting edge platforms offers a path for understanding the disease ecology of locations of interest in resource-poor countries. Our goal was to pilot a bio surveillance system comprising of rapid lateral flow immunoassays, rapid PCR and a cloud database. Methods The study was carried out in Bo, Sierra Leone at the Mercy Hospital. We recruited 1570 subjects over a period of two years. Inclusion criteria for the study were being febrile, being at least five years of age, living within the city of Bo or its neighbouring villages and agreeing to participate in the study. The assays used included a DPP multiplex lateral flow assay for dengue, Burkholderia pseudomallei , Yersinia pestis , malaria Pf/Pan, a Film Array PCR platform with multiplex Biothreat and SASFI panels that together detect over 30 pathogen targets. We used a Deki Reader to upload lateral flow images to the cloud database. The Deki reader quantitates test results, such that scores at ≥1.75 are considered positive. A special computer program was designed to upload pdf images of PCR results to the cloud database. The cloud database was designed for automated quality assessment and remote monitoring. Results Preliminary results show that out of 1570 samples processed by DPP, 30(1.9%) were positive for Burkholderia, 41(2.6%) were positive for Dengue NS1 antigen, 22(1.4%) were positive for Yesinia pestis fraction 1 antigen, and 340(21.7%) were positive for malaria. When a cross-section of results obtained by eye was compared with results automatically detected by the D2C platform, there was 95.2% concordance between results obtained by eye and those obtained automatically by the Deki reader to the cloud database. Conclusions Active disease surveillance and the ability to remotely monitor activities in peripheral health units are critical needs in many poor countries. Our results provide additional perspectives on the twin problem of surveillance and remote quality assessment.
From Academia to Government to Industry: Lessons Learned (2018)

Presented on October 31, 2018 at 11:00 a.m. in the Parker H. Petit Institute for Bioengineering and Bioscience (IBB) Atrium, Georgia Tech.
Genomic Analysis Reveals Multi-Drug Resistance Clusters in Group B Streptococcus CC17 Hypervirulent Isolates Causing Neonatal Invasive Disease in Southern Mainland China (2016)

Neonatal invasive disease caused by group B Streptococcus (GBS) represents a significant public health care concern globally. However, data related to disease burden, serotype distribution, and molecular epidemiology in China and other Asian countries are very few and specifically relative to confined regions. The aim of this study was to investigate the genetic characteristics of GBS isolates recovered from neonates with invasive disease during 2013-2014 at Guangzhou and Changsha hospitals in southern mainland China. We assessed the capsular polysaccharide type, pilus islands (PIs) distribution and hvgA gene presence in a panel of 26 neonatal clinical isolates, of which 8 were recovered from Early Onset Disease and 18 from Late Onset Disease (LOD). Among 26 isolates examined, five serotypes were identified. Type III was the most represented (15 cases), particularly among LOD strains (n = 11), followed by types Ib (n = 5), V (n = 3), Ia (n = 2) and II (n = 1). We performed whole-genome sequencing analysis and antimicrobial susceptibility testing on the 14 serotype III isolates belonging to the hypervirulent Clonal Complex 17 (serotype III-CC17). The presence of PI-2b alone was associated with 13 out of 14 serotype III-CC17 strains. Genome analysis led us to identify two multi-drug resistance gene clusters harbored in two new versions of integrative and conjugative elements (ICEs), carrying five or eight antibiotic resistance genes, respectively. These ICEs replaced the 16 kb-locus that normally contains the PI-1 operon. All isolates harboring the identified ICEs showed multiple resistances to aminoglycoside, macrolide, and tetracycline antibiotic classes. In conclusion, we report the first whole-genome sequence analysis of 14 GBS serotype III-CC17 strains isolated in China, representing the most prevalent lineage causing neonatal invasive disease. The acquisition of newly identified ICEs conferring multiple antibiotic resistance could in part explain the spread of this specific clone among Chinese neonatal isolates and underlines the need for a constant epidemiological surveillance.
Efficient radiation production in a weakly ionized, low-pressure, nonequilibrium gallium-iodide positive column discharge plasma (2007)

Electric-discharge plasmas in gallium-iodide vapours are experimentally found to convert 40% of input electric power into ultraviolet and visible radiation (200–800 nm). The conditions are a weakly ionized positive column consisting of 5–10 Torr argon, and the gallium-iodide vapour is formed by heating condensed gallium-iodide to 100–120 °C. The input power density is 50–100 mW cm−3. The plasma is contained in a sealed silica tube and excited by an external radiofrequency antenna. Computational analysis and plasma diagnostics lead to a quantitative understanding that gallium atoms are formed by electron-impact dissociation of gallium-iodide compounds that evaporate into the plasma volume, and that further electron collisions excite the gallium atoms, which then decay by photon emission. High efficiency is possible only because several photons are emitted per dissociation event, and because nonradiative power channels such as electron-impact elastic heating and vibrational excitation are not dominant. The dissociated species recombine on the wall to reform the species that evaporates. The plasma properties change discontinuously as the molar ratio of iodine to gallium (I/Ga) in the system crosses the values I/Ga = 3 and I/Ga = 2, consistent with the thermodynamic properties of condensed gallium-iodide compounds.
ATT BLI UTSATT FÖR VÅLD OCH HOT INOM AKUTVÅRDEN - SJUKSKÖTERSKORS ERFARENHETER (2017)

Bakgrund: Våld och hot har länge varit ett växande problem inom svenskt arbetsliv, med sjukvårdspersonal som en överrepresenterad yrkeskategori gällande anmälningar till Arbetsmiljöverket. Arbetsgivaren har en skyldighet enligt arbetsmiljölagen att förebygga olycksfall och ohälsa, samt arbeta för en god arbetsmiljö. Akutavdelningar är ofta förknippade med oro och ängslighet vilket tros vara en anledning till ökad risk för konflikt i denna miljö. Att utsättas för hot och våld är en kraftig stressor för de flesta individer och både hot och våld på arbetet har relaterats till utbrändhet. Syfte: Att belysa sjuksköterskors erfarenheter av att ha blivit utsatta för hot och våld inom akutvården. Metod: En litteraturstudie innehållande 13 artiklar med kvalitativ ansats, som inhämtades efter databassökningar i CINAHL, PubMed och PsycINFO. Analys gjordes i enlighet med Forsberg &amp; Wengströms innehållsanalys och genererade fyra övergripande teman: ”Våldets former”, ”Bidragande faktorer vid våld”, ”Upplevelser av organisationsproblem” och ”Konsekvenser av hot och våld”. Resultat: Att ha utsatts för hot och våld förknippades med oro och sorg men även skam över ett professionellt misslyckande. Stöd söktes ofta hos kollegor men effektiva copingstrategier fanns inte alltid till hands. Misstro mot ledning fanns i många fall och detta kunde avspeglas i valet att inte rapportera händelser. Konklusion: Att ha utsatts för våld och hot var något som ofta gav långvariga effekter så som konstant oro och förlust av kärlek till jobbet.
Clinical Characteristics and Management of Late Urinary Symptom Flare Following Stereotactic Body Radiation Therapy for Prostate Cancer (2014)

In this study, we characterize late urinary symptom flare following SBRT. Late urinary symptom flare is a constellation of symptoms including urinary frequency/urgency, weak stream, and dysuria that transiently occurs 6-18 months post-SBRT. Provision of appropriate anticipatory counseling and the maintenance of prophylactic alpha-antagonists may limit the bother associated with this syndrome.
Selective binding and reversible release of riboflavin by polymer-bound zinc(ii) azamacrocycles (2001)

The reversible formation of a coordinative bond between a polymer-bound Lewis-acidic metal complex and a flavin imide moiety allows complete extraction of riboflavin from aqueous solution at physiological pH and its quantitative release at pH 5.
Brick‐wall antenna in multilayer thin‐film technology (1998)

In this letter, a brick-wall slot antenna fed by CPW and built in a multilayer thin-film technology, like that used in MCM-D, is studied. This technology uses several thin-film conductor and dielectric layers deposited over the substrate. The effect of the thin dielectric films on the antenna performance is studied. The analysis is carried out both theoretically and experimentally. The presented results include the return loss, the radiation patterns, and the antenna gain. © 1998 John Wiley & Sons, Inc. Microwave Opt Technol Lett 19: 360–365, 1998.
Modulation of the Vault Protein-Protein Interaction for Tuning of Molecular Release (2017)

Vaults are naturally occurring ovoid nanoparticles constructed from a protein shell that is composed of multiple copies of major vault protein (MVP). The vault-interacting domain of vault poly(ADP-ribose)-polymerase (INT) has been used as a shuttle to pack biomolecular cargo in the vault lumen. However, the interaction between INT and MVP is poorly understood. It is hypothesized that the release rate of biomolecular cargo from the vault lumen is related to the interaction between MVP and INT. To tune the release of molecular cargos from the vault nanoparticles, we determined the interactions between the isolated INT-interacting MVP domains (iMVP) and wild-type INT and compared them to two structurally modified INT: 15-amino acid deletion at the C terminus (INTΔC15) and histidine substituted at the interaction surface (INT/DSA/3 H) to impart a pH-sensitive response. The apparent affinity constants determined using surface plasmon resonance (SPR) biosensor technology are 262 ± 4 nM for iMVP/INT, 1800 ± 160 nM for iMVP/INTΔC15 at pH 7.4. The INT/DSA/3 H exhibits stronger affinity to iMVP (K <sub>Dapp</sub> = 24 nM) and dissociates at a slower rate than wild-type INT at pH 6.0.
Real-Time Dual-Wavelength Time-Resolved Diffuse Optical Tomography System for Functional Brain Imaging Based on Probe-Hosted Silicon Photomultipliers (2020)

Near-infrared diffuse optical tomography is a non-invasive photonics-based imaging technology suited to functional brain imaging applications. Recent developments have proved that it is possible to build a compact time-domain diffuse optical tomography system based on silicon photomultipliers (SiPM) detectors. The system presented in this paper was equipped with the same eight SiPM probe-hosted detectors, but was upgraded with six injection fibers to shine the sample at several points. Moreover, an automatic switch was included enabling a complete measurement to be performed in less than one second. Further, the system was provided with a dual-wavelength ( 670 n m and 820 n m ) light source to quantify the oxy- and deoxy-hemoglobin concentration evolution in the tissue. This novel system was challenged against a solid phantom experiment, and two in-vivo tests, namely arm occlusion and motor cortex brain activation. The results show that the tomographic system makes it possible to follow the evolution of brain activation over time with a 1 s -resolution.
Generation of pulses as short as 93 fs from self-starting femtosecond Cr:LiSrAlF_6 lasers by exploiting multiple-quantum-well absorbers (1993)

A Cr:LiSrAIF(6) laser has been mode locked by using a multiple-quantum-well (MQW) absorber. With the MQW absorber inside the laser cavity, Kerr lens mode locking is initiated, yielding transform-limited pulses as short as 93 fs. Pulses of 500-fs duration have also been produced by using resonant passive mode locking with the MQW absorber in an external cavity.
Human Antibody Responses Following Vaccinia Immunization Using Protein Microarrays and Correlation With Cell-Mediated Immunity and Antibody-Dependent Cellular Cytotoxicity Responses (2021)

NCT00914732.
Degree of polarization (uniformity) and depolarization index: unambiguous depolarization contrast for optical coherence tomography (2015)

The degree of polarization (uniformity) has attracted increased interest as a functional contrast in optical coherence tomography (OCT). However, its computation from a single polarization state suggests an ambiguity that is strongly dependent on a sample's orientation. We here propose an improved metric to present depolarization with respect to the optical system rather than the propagating field. Using numerical simulations and optical frequency domain imaging, we evaluate the conventional DOP(U) for different polarization states and compare its performance with the unambiguous depolarization index.