gebhart/patrepeval huggingface dataset:
Ultra-wideband statistical channel model for non line of sight millimeter-wave urban channels (2014)

This paper presents ultra-wideband statistical spatial and omnidirectional channel models for 28 GHz millimeter-wave cellular dense urban Non-Line of Sight (NLOS) environments, developed from wideband measurements in New York City that used synthesized timing from 3D ray-tracing. An accurate 3GPP-like channel model has been developed, where model parameters are based on empirical distributions for time cluster and spatial (lobe) channel parameters. A statistical simulator capable of reproducing the joint temporal and spatial measured channel statistics is given here. A step-by-step procedure for generating channel coefficients is shown to validate measured statistics from 28 GHz field measurements, thus validating our statistical channel model, for use in standard bodies and system-level simulations for millimeter-wave wideband communications.
JNJ-64041757 (JNJ-757), a Live, Attenuated, Double-Deleted Listeria monocytogenes–Based Immunotherapy in Patients With NSCLC: Results From Two Phase 1 Studies (2020)

As monotherapy, JNJ-757 was immunogenic and tolerable, with mild infusion-related fever and chills. The limited efficacy of JNJ-757, alone or with nivolumab, did not warrant further investigation of the combination.
ChemInform Abstract: Structure and Photoluminescence Properties of Ce3+‐Doped Novel Silicon‐Oxynitride Ba4‐zMzSi8O20‐3xN2x (M: Mg, Ca, Sr). (2011)

Abstract The undoped and Ce 3+ ‐doped title compounds are prepared by solid state reactions using Si 3 N 4 , SiO 2 , BaCO 3 , MgO, CaCO 3 , SrCO 3 , and CeO 2 as starting materials (BN boat, 1050—1300 °C, N 2 /5% H 2 ).
An In-Depth Investigation of Physical Mechanisms Governing SANOS Memories Characteristics (2009)

The goal of this work is to give a clear physical comprehension of the charge loss mechanisms of SANOS (Si/Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> /Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> /SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> /Si) memories. Retention at room and high temperature is investigated on different samples through experiments and theoretical modeling. We argue that at room temperature, the charge loss essentially results from the tunneling of the electrons trapped at the nitride interface, and the retention life time increases with the nitride thickness. On the contrary, at high temperature, the trapped charges in the nitride volume quickly redistribute, thanks to the thermal emission process, and they migrate to the nitride interface. Indeed, this result suggests that thin-nitride thicknesses in SANOS devices allow keeping a fast program/erase speed without degrading the retention at high temperature.
744 Manipulation of a Multi-fingered Hand using Discernment of Operation by EMG Signals (2004)

In this research, the control technique of the robot hand, which used EMG signals measured on the skin surface, was proposed. The signals corresponding to motions were quantitatively generated from EMG signals using linear multiple regression models. A learning process is needed in this method, but it takes only a short time. By using the generated signals, discernment of hand motions and adjustment of grasping force were realized. In this paper, In order to prove the validity of this technique, the experiment, which used the robot hand, was conducted. And subjects was able to adjust grasping force with this method.
Reversible epitaxial electrodeposition of metals in battery anodes (2019)

The propensity of metals to form irregular and nonplanar electrodeposits at liquid-solid interfaces has emerged as a fundamental barrier to high-energy, rechargeable batteries that use metal anodes. We report an epitaxial mechanism to regulate nucleation, growth, and reversibility of metal anodes. The crystallographic, surface texturing, and electrochemical criteria for reversible epitaxial electrodeposition of metals are defined and their effectiveness demonstrated by using zinc (Zn), a safe, low-cost, and energy-dense battery anode material. Graphene, with a low lattice mismatch for Zn, is shown to be effective in driving deposition of Zn with a locked crystallographic orientation relation. The resultant epitaxial Zn anodes achieve exceptional reversibility over thousands of cycles at moderate and high rates. Reversible electrochemical epitaxy of metals provides a general pathway toward energy-dense batteries with high reversibility.
Structure and Stability of Low Pressure Chemically Vapor‐Deposited Silicon Films (1978)

The structure of silicon films deposited by low pressure, chemical vapor deposition in the 600°C temperature range has been investigated by x‐ray diffraction and transmission electron microscopy. There is a critical temperature near 600°C, above which the deposited films are polycrystalline and below which amorphous films are obtained. This temperature is close to that used to deposit films for integrated circuit applications. When the films are polycrystalline, the <110> texture dominates. The polycrystalline films are reasonably stable upon annealing to temperatures up to approximately 1100°C. The initially amorphous films, however, easily crystallize. Crystallization has been observed to be well advanced after annealing at 800°C. Large stresses are built into the amorphous films, while the stresses in the polycrystalline films are lower.
Suppression of Interference-Induced Reflectivity Fluctuations in GaN-Based Semiconductor Saturable Absorber Mirror (2008)

10.1149/1.2885019
Endoscopic ultrasound elastography for evaluation of lymph nodes and pancreatic masses: A multicenter study (2009)

EUS elastography is superior compared to conventional B-mode imaging and appears to be able to distinguish benign from malignant pancreatic masses and lymph nodes with a high sensitivity, specificity and accuracy. It might be reserved as a second line examination to help characterise pancreatic masses after negative EUS-FNA and might increase the yield of EUS-FNA for lymph nodes.
Coinhibitory receptors and CD8 T cell exhaustion in chronic infections (2014)

Revealing the molecular basis of virus-specific CD8 T cell exhaustion in chronic infections is critical for the understanding of the disease pathogenesis and the designing of novel vaccines aiming to enhance the cytolytic arm of the immune system. This is of particular interest for the development of immunotherapies in the context of a functional cure for HIV.
Nonintrusive Gas-Turbine Engine-Exhaust Characterization Using Acoustic Measurements (2017)

This paper reports exhaust measurements performed using a nonintrusive acoustic technique on a JT15D-1A turbofan research engine. Using multiple streamwise displaced microphones, the integrated exhaust velocity and static temperature were measured simultaneously in engine flows with bypass Mach numbers up to 0.48. A Kiel pressure and K-type thermocouple probe was used to assess the accuracy of the acoustic measurements. The Integrated velocity and static temperature rms errors of and 2.3 K were identified. Using probe-based measurements at a low engine power setting, two calibration constants were identified for conversion from integrated flow parameters to mass flow and thrust. Applying the calibration constants to the acoustic measurements, and 200 N rms errors in mass flow and thrust were observed. These promising results indicate that the acoustic technique may be used to characterize and monitor gas-turbine engine performance. To the authors’ knowledge, this is the first time a nonintrusive acoustic technique has been used to characterize engine flows with Mach numbers greater than 0.3.
Investigations of Work Function Shift in Lanthanum Silicate High-K Dielectric MIS Capacitors (2007)

The effective work function for lanthanum silicate high-k dielectric MIS capacitors with TaN electrodes is reported in comparison to devices with thin lanthanum oxide capping layers on HfSiO and HfSiON dielectric layers. For the hafnium-based dielectrics, La 2 O 3 capping results in a V fb shift of up to -184 mV after a 1000 {degree sign}C, 5 sec anneal in nitrogen. LaSiO x films were formed by reacting La 2 O 3 and a chemical oxide. Annealing of these films resulted in a negative V fb shift of higher magnitude. Ozone or ammonia pretreatment of the chemical oxide prior to silicate formation reduces the magnitude of the shift, allowing for effective work function values between 3.75 and 4.25 eV after annealing. After a 700 {degree sign} C, 10 sec anneal, work function tuning of +/- 150 mV was a achieved while maintaining EOT (0.9 nm) and leakage (0.6 A/cm 2 at V fb + 1 V) for all samples with and without pretreatments.
THE PRODUCTION OF APOSYMBIOTIC HYDRA BY THE PHOTODESTRUCTION OF GREEN HYDRA ZOOCHLORELLAE (1976)

1. Florida strain, but not the English strain of green hydra, are bleached by light at 620 watts/m2.2. English strain animals are bleached at 620 watts/m2 in the presence of DCMU (a photosynthetic inhibitor) which also increases the bleaching effect in Florida hydra. English animals are also bleached by irradiation with 1900 watts/m2.3. Aposymbiotic clones that remain algal-free may be grown from bleached animals of both Florida and English strains.4. Florida strain hydra containing English algae are bleached at 620 watts/m2 but English hydra containing Florida algae are not.5. The bleaching of Florida hydra takes place with light occurring in red region of the visible spectrum and probably involves the photodestruction of the photosynthetic system of the algal symbionts.6. The bleaching of green hydra ultimately results from the removal of symbionts from the host's digestive cells.
Indoor mm-Wave Channel Measurements: Comparative Study of 2.9 GHz and 29 GHz (2015)

The millimeter-wave (mm-Wave) frequency band ~30-300 GHz has received significant attention lately as a prospective band for 5G systems. Millimeter-wave frequencies have traditionally been used for backhaul, satellite and other fixed services. While these bands offer substantial amount of bandwidth and opportunity for spatial multiplexing, the propagation characteristics for terrestrial mobile usage need to be fully understood prior to system design. Towards this end, this paper presents preliminary indoor measurement results obtained using a channel sounder equipped with omni- and directional antennas at 2.9 GHz and 29 GHz as a comparative study of the two bands. The measurements are made within a Qualcomm building in Bridgewater, NJ, USA, for two separate floors, each representing a different yet representative type of office plan. We present measurements and estimated parameters for path loss, excess delay, RMS delay and analyze the power profile of received paths. In addition, we present several spherical scans of particular links to illustrate the 3-D angular spread of the received paths. This work represents initial results of an ongoing effort for comprehensive indoor and outdoor channel measurements. The measurements presented here, along with cited references, offer interesting insights into propagation conditions (e.g. loss, delay/angular spread etc.), coverage and robustness for mobile use of millimeter-wave bands. We believe additional extensive measurement campaigns in diverse settings by academia and industry would help facilitate the generation of usable channel models.
The rise and fall of SARS-CoV-2 variants and the emergence of competing Omicron lineages (2022)

Abstract In late December of 2019, high throughput sequencing technologies enabled rapid identification of SARS-CoV-2 as the etiological agent of COVID-19, and global sequencing efforts are now a critical tool for monitoring the ongoing spread and evolution of this virus. Here, we analyze a subset (n=83,204) of all publicly available SARS-CoV-2 genomes (n=~5.6 million) that were randomly selected, but equally distributed over the course of the pandemic. We plot the emergence and extinction of new variants of concern (VOCs) over time and show how this corresponds to the ongoing accumulation of mutations in SARS-CoV-2 genomes and individual proteins. While the accumulation of mutations generally follows a linear regression, non-synonymous mutations are significantly greater in Omicron viruses than in previous variants–especially in the spike and nucleoproteins–and these differences are more pronounced in a recently identified sub-lineage (BA.2) of Omicron. Importance Omicron is the fifth SARS-CoV-2 variant to be designated a Variant of Concern (VOC) by the World Health Organization (WHO). Here we provide a retrospective analysis of SARS-CoV-2 variants and explain how the Omicron variant is distinct. Our work shows that the spike and nucleoproteins have accumulated the most mutations in Omicron variants, but that the accessory proteins of SARS-CoV-2 sequences are changing most rapidly relative to their size. Collectively, this “Observation” provides a concise overview of SARS-CoV-2 evolution, reveals mutational differences between two Omicron lineages, and highlights changes in the SARS-CoV-2 proteome that have been under reported.
Crystal structure of RNA polymerase II from Komagataella pastoris (2017)

RNA polymerase II (Pol II) is a 12-subunit protein complex that conducts the transcription of mRNA and some small RNAs. In this work, the crystal structure of Pol II from the methylotropic yeast Komagataella pastoris (Pichia pastoris) was determined. While the structure is highly homologous to that of Pol II from the budding yeast Saccharomyces cerevisiae, the stalk and clamp modules of the K. pastoris Pol II displayed large inward rotations, closing the central cleft to a greater extent than in the known S. cerevisiae Pol II structures. The conformational differences reflect the inherent flexibilities of the stalk and the clamp, as additional low-resolution structures of K. pastoris Pol II in different crystal forms revealed diverse stalk and clamp orientations. Comparisons with other eukaryotic/archaeal RNA polymerase structures in the Protein Data Bank revealed the distributions of the stalk and clamp orientations. The conformational plasticity should be essential for transcriptional functions and binding various regulatory factors.
Solution processed efficient orange phosphorescent organic light-emitting device with small molecule host (2009)

We present excellent orange red dopants, carbazole-phenylquinoline-based Ir(III) complexes, with a small molecule host system for highly efficient solution processed phosphorescent orange devices. A hole type material of m-MTDATA (4, 4', 4''-tri-(N-3-methylphenyl-N-phenylamino)triphenylamine) and a TPBI (2, 2', 2''-(1,3,5-phenylene)tris(1-phenyl-1H-benzimidazole)) electron transporting material are employed as a soluble small molecule mixed host for these orange devices. Maximum current- and power-efficiency values of 20.0 cd A−1 and 16.8 lm W−1 and maximum external quantum efficiency of 10.8% are demonstrated. Results reveal a practical way to fabricate the highly efficient orange solution processed phosphorescent organic devices, useful for low cost production of white light-emitting devices.
Design of CMOS adaptive-bandwidth PLL/DLLs: a general approach (2003)

A phase-locked loop (PLL) and delay-locked loop (DLL) design with adaptively adjusting bandwidth enables optimal performance over a wide frequency range and across process, voltage, and temperature variations. A design methodology of such adaptive-bandwidth PLLs and DLLs is described. To assess the impact of each circuit parameter directly, we derive a discrete-time, open-loop dynamic model of the PLL/DLL that characterizes the change in output variables in response to the sampled error and we express the adaptive-bandwidth criteria in terms of the open-loop gains, instead of the traditional closed-loop parameters, /spl omega//sub n/ and /spl zeta/. Applying these criteria, we derive scaling equations for the charge-pump current and filter resistance that achieve adaptive bandwidth in charge-pump PLL/DLLs. We show that previously published adaptive-bandwidth PLL/DLLs, a self-biased PLL/DLL and a regulated-supply PLL/DLL, rely on the small-signal conductance tracking the large-signal conductance of the voltage-controlled oscillator/voltage-controlled delay-line and, thus, sustain constant /spl omega//sub n///spl omega//sub ref/ and /spl zeta/ only if the voltage swing is sufficiently higher than the device threshold voltage V/sub TH/. The paper also presents procedures to estimate the open-loop parameters from an open-loop impulse response of the PLL/DLL.
mobileVision: Towards a patient-operable, at-home, non-mydriatic retinal imaging system (2013)

We present our work towards a patient-operable, at-home, non-mydriatic retinal imaging system. Early detection of ocular diseases like diabetic retinopathy is facilitated by retinal examinations that typically include imaging conducted by experienced examiners using sophisticated and expensive equipment. This creates a barrier to care for patients, preventing retinal examinations and leading to worse patient outcomes. To address this problem, we propose a system operated directly by the patient; a specialist need not be present. An adjustable fixation target, indirect imaging optics, and a self-contained illumination system comprise a robust yet compact attachment which affixes to the patient's smartphone. This allows the smartphone's camera to acquire digital retinal images (1MP, 23 degree, 10um resolution) under controlled eye rotation while preserving eye-camera pupil matching through mechanically constrained translation of the optics. A software application downloaded to the smartphone assists the user in imaging pre-set retinal fields: it automatically controls the fixation target and illumination while giving verbal instructions. The software combines the resulting image sequence to form a 60 degree retinal panorama which can be sent electronically to a health care provider for remote viewing. We have constructed and used a preliminary prototype to image rat and human eyes in vivo. Our aim is to enable untrained persons to image their own retinas and those of others, thereby reducing burdensome demand for both health care providers and costly imaging instrumentation. This device has the potential to become a valuable tool for self-monitoring in patients requiring frequent retinal examinations.
Sacubitril/Valsartan Ameliorates Cardiac Hypertrophy and Preserves Diastolic Function in Cardiac Pressure Overload (2021)

In a model of HFpEF induced by cardiac pressure overload, sac/val reduced hypertrophy compared with valsartan alone and ameliorated diastolic dysfunction. These effects were independent of blood pressure. Early systolic dysfunction was not affected, supporting the notion that sac/val has the largest potential in conditions characterized by reduced ejection fraction. Observed anti-hypertrophic effects in preserved ejection fraction implicate potential benefit of sac/val in the clinical setting of hypertrophic remodelling and impaired diastolic function.
Rotational alignment of NO desorbing from Pt(111) (1987)

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Modeling Correspondences for Multi-Camera Tracking Using Nonlinear Manifold Learning and Target Dynamics (2006)

Multi-camera tracking systems often must maintain consistent identity labels of the targets across views to recover 3D trajectories and fully take advantage of the additional information available from the multiple sensors. Previous approaches to the "correspondence across views" problem include matching features, using camera calibration information, and computing homographies between views under the assumption that the world is planar. However, it can be difficult to match features across significantly different views. Furthermore, calibration information is not always available and planar world hypothesis can be too restrictive. In this paper, a new approach is presented for matching correspondences based on the use of nonlinear manifold learning and system dynamics identification. The proposed approach does not require similar views, calibration nor geometric assumptions of the 3D environment, and is robust to noise and occlusion. Experimental results demonstrate the use of this approach to generate and predict views in cases where identity labels become ambiguous.
A comparative study of the neuropsychiatric and neurocognitive phenotype in two microdeletion syndromes: Velocardiofacial (22q11.2 deletion) and Williams (7q11.23 deletion) syndromes (2013)

These findings offer a wide perspective on unique versus common phenotypes in 22q11.2DS and WS.
Ethnicity affects EGFR and KRAS gene alterations of lung adenocarcinoma (2015)

Mutations or copy number gains (CNGs) of the <i>EGFR</i> and <i>KRAS</i> genes are representative alterations in lung adenocarcinomas that are individually associated with patient characteristics such as ethnicity, smoking status and gender. However, the effects of combinations of these genetic alterations have not been statistically examined. The present study analyzed previously examined lung adenocarcinoma cases in Asian (n=166) and non-Asian (n=136) individuals in whom all four <i>EGFR</i> and <i>KRAS</i> alterations had been studied. The polynomial logistic regression models were used following adjustment for gender and smoking status, and using patients without any type of <i>EGFR</i>/<i>KRAS</i> alterations as a reference. Between the two ethnic groups, <i>EGFR</i> CNGs (g<i>EGFR</i>) occurred more frequently than <i>EGFR</i> mutations (m<i>EGFR</i>) (46 vs. 38% in Asians; 21 vs. 10% in non-Asians), whereas <i>KRAS</i> mutations (m<i>KRAS</i>) were more frequent than <i>KRAS</i> CNGs (g<i>KRAS</i>) (13 vs. 7% and 35 vs. 4%, respectively). Additionally, g<i>EGFR</i> and g<i>KRAS</i> occurred significantly more frequently in respective mutant cases, and all <i>EGFR</i> alterations were almost exclusive of all <i>KRAS</i> alterations. The polynomial logistic regression models confirmed that all types of <i>EGFR</i> alterations were significantly more frequent among Asian individuals than among non-Asian individuals, independent of gender and smoking status (odds ratios, 2.36-6.67). <i>KRAS</i> alterations occurred less frequently among Asian individuals than among non-Asian individuals, although a significant difference was not detected. The present study results indicated that the <i>EGFR</i> and <i>KRAS</i> profiles, including mutations and CNGs, differ between Asian and non-Asian individuals with lung adenocarcinoma, suggesting that ethnicity strongly affects the molecular characteristics of lung adenocarcinoma.