gebhart/patrepeval huggingface dataset:
Conferencing3: 3D audio conferencing and archiving services for handheld wireless devices (2005)

Despite the heavy dependence upon contemporary teleconferencing systems by the business community, the user experience can be less than adequate. This paper describes a framework called Conferencing3, which leverages 3D audio spatialisation offering greater clarity, improved distinguishability between the individual participants, a personalisable audio listening space and the ability to add indexes with text descriptors into the conference. To the knowledge of the authors, this is the first reported mobile solution offering interactive 3D, both audio and graphical, support for conferencing on commercially available wireless devices. In addition, a unique approach is offered for 3D visualisation and browsing of archived sessions.
Correct splicing of a group II intron from a chimeric reporter gene transcript in tobacco plastids (1995)

An in vivo test system was developed to study group II intron splicing in higher plant chloroplasts. The chimeric reporter gene uidA was constructed by translational fusion of an intron-containing segment of the plastid atpF gene with the coding region of a plastid uidA reporter gene. The chimeric uidA gene was inserted into the tobacco plastid genome by the biolistic transformation procedure using a plastid targeting vector. Correct intron excision was confirmed by Northern blot analysis, by sequencing amplified cDNAs and by accumulation of the encoded beta-glucuronidase (GUS), the expression of which was dependent on intron removal. Removal of the intron from the uidA mRNA is less efficient (< 50%) than from the atpF mRNA (> 90%). The efficiency of atpF mRNA splicing is not affected in the plasmid transformants indicating that inefficient splicing of the highly-expressed uidA mRNA is not due to depletion of factor(s) required for the atpF intron removal. A derivative of uidA, with a stop codon introduced into the loop of domain VI, was also tested. The mutations did not affect the splicing efficiency. The chimeric uidA splicing system will facilitate the study of structural and sequence requirements for group II intron splicing in plastids of higher plants.
Potent Inhibitors of Furin and Furin-like Proprotein Convertases Containing Decarboxylated P1 Arginine Mimetics (2009)

Furin belongs to the family of proprotein convertases (PCs) and is involved in numerous normal physiological and pathogenic processes, such as viral propagation, bacterial toxin activation, cancer, and metastasis. Furin and related furin-like PCs cleave their substrates at characteristic multibasic consensus sequences, preferentially after an arginine residue. By incorporating decarboxylated arginine mimetics in the P1 position of substrate analogue peptidic inhibitors, we could identify highly potent furin inhibitors. The most potent compound, phenylacetyl-Arg-Val-Arg-4-amidinobenzylamide (15), inhibits furin with a K(i) value of 0.81 nM and has also comparable affinity to other PCs like PC1/3, PACE4, and PC5/6, whereas PC2 and PC7 or trypsin-like serine proteases were poorly affected. In fowl plague virus (influenza A, H7N1)-infected MDCK cells, inhibitor 15 inhibited proteolytic hemagglutinin cleavage and was able to reduce virus propagation in a long-term infection test. Molecular modeling revealed several key interactions of the 4-amidinobenzylamide residue in the S1 pocket of furin contributing to the excellent affinity of these inhibitors.
Electric Propulsion Research and Development at JPL (2005)

In this paper, we will describe the electronic propulsion technologies of interest and our role in developing and interjecting these technologies into JPL missions.
Mobile enablement of business process management suites (2014)

Mobile capabilities are expected to fundamentally change the way enterprises operate. However, enterprises encounter technical challenges in mobile enablement of their existing software products. Among the challenges are user experience optimized for mobile, security, management of mobile applications. In this paper we describe technical challenges and solutions in mobile enablement of Business Process Management products, and, in particular, integration of Business Process Management Suites with Mobile Enterprise Application Platforms.
Expression of Protein Kinase C Genes during Ontogenic Development of the Central Nervous System (1989)

We have analyzed the RNA expression of three protein kinase C (PKC) genes (alpha, beta, and gamma) in human and murine central nervous systems during embryonic-fetal, perinatal, and adult life. Analysis of human brain poly(A)+ RNA indicates that expression of PKC alpha and beta genes can be detected as early as 6 weeks postconception, undergoes a gradual increase until 9 weeks postconception, and reaches its highest level in the adult stage, and that the PKC gamma gene, although not expressed during embryonic and early fetal development, is abundantly expressed in the adult period. Similar developmental patterns were observed in human spinal cord and medulla oblongata. A detailed analysis of PKC gene expression during mammalian ontogeny was performed on poly(A)+ RNA from the brain cells of murine embryos at different stages of development and the brain cells of neonatal and adult mice. The ontogenetic patterns were similar to those observed for human brain. Furthermore, we observed that the expression of PKC gamma is induced in the peri- and postnatal phases. These results suggest that expression of PKC alpha, beta, and gamma genes possibly mediates the development of central neuronal functions, and expression of PKC gamma in particular may be involved in the development of peri- and postnatal functions.
Amphiphilic Surface Active Triblock Copolymers with Mixed Hydrophobic and Hydrophilic Side Chains for Tuned Marine Fouling-Release Properties (2010)

Two series of amphiphilic triblock surface active block copolymers (SABCs) were prepared through chemical modification of two polystyrene-block-poly(ethylene-ran-butylene)-block-polyisoprene ABC triblock copolymer precursors. The methyl ether of poly(ethylene glycol) [M(n) approximately 550 g/mol (PEG550)] and a semifluorinated alcohol (CF(3)(CF(2))(9)(CH(2))(10)OH) [F10H10] were attached at different molar ratios to impart both hydrophobic and hydrophilic groups to the isoprene segment. Coatings on glass slides consisting of a thin layer of the amphiphilic SABC deposited on a thicker layer of an ABA polystyrene-block-poly(ethylene-ran-butylene)-block-polystyrene thermoplastic elastomer were prepared for biofouling assays with algae. Dynamic water contact angle analysis, X-ray photoelectron spectroscopy (XPS) and near-edge X-ray absorption fine structure (NEXAFS) measurements were utilized to characterize the surfaces. Clear differences in surface structure were realized as the composition of attached side chains was varied. In biofouling assays, the settlement (attachment) of zoospores of the green alga Ulva was higher for surfaces incorporating a large proportion of the hydrophobic F10H10 side chains, while surfaces with a large proportion of the PEG550 side chains inhibited settlement. The trend in attachment strength of sporelings (young plants) of Ulva did not show such an obvious pattern. However, amphiphilic SABCs incorporating a mixture of PEG550 and F10H10 side chains performed the best. The number of cells of the diatom Navicula attached after exposure to flow decreased as the content of PEG550 to F10H10 side chains increased.
Validation of a crystal detector model for the calibration of the Large Signal Network Analyzer (2007)

If the large signal network analyser [W. Van Moer, Y. Rolain, A large-signal network analyzer: why is it needed? IEEE Microwave Magazine,Vol. 7, No. 6, pp. 46-62, 2006] is used to measure the waveforms present at the device ports, two additional calibration steps, a power and a phase calibration, are needed besides the classical linear SOLT-calibration. The aim of this paper is to estimate and validate a parametric black-box model for a crystal detector. This detector is used as a reference element to calibrate the phase distortion of a LSNA operating under narrow band modulated excitation.
Alkoxy‐Functionalized Thienyl‐Vinylene Polymers for Field‐Effect Transistors and All‐Polymer Solar Cells (2014)

π‐conjugated polymers based on the electron‐neutral alkoxy‐functionalized thienyl‐vinylene (TVTOEt) building‐block co‐polymerized, with either BDT (benzodithiophene) or T2 (dithiophene) donor blocks, or NDI (naphthalenediimide) as an acceptor block, are synthesized and characterized. The effect of BDT and NDI substituents (alkyl vs alkoxy or linear vs branched) on the polymer performance in organic thin film transistors (OTFTs) and all‐polymer organic photovoltaic (OPV) cells is reported. Co‐monomer selection and backbone functionalization substantially modifies the polymer MO energies, thin film morphology, and charge transport properties, as indicated by electrochemistry, optical spectroscopy, X‐ray diffraction, AFM, DFT calculations, and TFT response. When polymer P7 is used as an OPV acceptor with PTB7 as a donor, the corresponding blend yields TFTs with ambipolar mobilities of μ e = 5.1 × 10 −3 cm 2 V –1 s –1 and μ h = 3.9 × 10 −3 cm 2 V –1 s –1 in ambient, among the highest mobilities reported to date for all‐polymer bulk heterojunction TFTs, and all‐polymer solar cells with a power conversion efficiency (PCE) of 1.70%, the highest reported PCE to date for an NDI‐polymer acceptor system. The stable transport characteristics in ambient and promising solar cell performance make NDI‐type materials promising acceptors for all‐polymer solar cell applications.
An integral path self-calibration scheme for a 20.1&#x2013;26.7GHz dual-loop PLL in 32nm SOI CMOS (2012)

A bandwidth self-calibration scheme is introduced as part of a 20.1GHz to 26.7GHz, low noise PLL in 32nm CMOS SOI. A dual-loop architecture in combination with an integral path measurement and correction scheme desensitizes the loop transfer function to the VCO's small signal gain variations. The spread of gain peaking is reduced by self-calibration from 2.4dB to 1dB, when measured at 70 sites on a 300mm wafer. The PLL has a measured phase noise @10MHz offset of -126.5dBc/Hz at 20.1GHz.
Effect of Activation of Soil Microbes on Electromigration according to the Characteristics of the Media of Pb and Cu by Bio-electrokinetics (2013)

유해한 중금속으로 오염된 토양을 정화하기 위하여 고려된 유망한 기술은 동전기정화법이다. 정화 과정을 개선하기 위하여 몇가지를 수정하여 연구하게 되었다. 본 연구에서는 중금속으로 오염된 지역의 토양 및 지하수에 동전기적 기술을 사용하고 배양된 금속환원 미생물과 영양분을 주입하여 토양 내의 토착 미생물을 활성화하여 납과 구리의 이동도를 상승시키는 것이 목표이며, 연구 결과 전체적으로 배양액 중 배양된 금속환원 미생물의 부피를 75%로 맞추었을 때 제거효율이 가장 크게 나오는 것을 확인했고, 배양액으로 <TEX>${NO_3}^-$</TEX>를 사용하여 배양된 금속환원 미생물군의 중금속 제거 능력이 다소 뛰어남을 알 수 있었으며, 기존의 동전기법과 비교하여 이동도가 60~70% 상승함을 확인하였다. Electrokinetic has been considered a promising technology to remediate soils contaminated with toxic heavy metals. Several modifications have been studied to improve the remediation processes. In this study, bio-electrokinetic(BEK) process which stands for electrokinetic process combinded with activated soil bacteria was proposed and environmentally evaluated for enhancement of Pb and Cu migration rates by using culture media solution instead of the electrolyte solution. Five different types of the solutions for each phases were used at different culture media and electrolyte ratios (v/v) with 1:0, 0:1, 3:1, 1:1 and 1:3 for phase 1, 2, 3, 4 and 5, respectively. In addition, experiments were conducted for the ratios between soil microbes and electrolyte at 90% and 80%. In the experiments using electrolyte of containing <TEX>${NO_3}^-$</TEX>, the concentrations of leed and copper in the soil at section-1 is relatively lower than that of section-6 since heavy metal components moves from the cathode electrode to the anode electrode. Also the migration rate of lead and copper is high at phase 3. In the experiments using electrolyte of containing <TEX>${NO_2}^-$</TEX>, the migration rate of lead and copper is relatively lower than that of using electrolyte of containing <TEX>${NO_3}^-$</TEX>. Overall results demonstrated that the heavy metal removal efficiency using electrolyte of containing <TEX>${NO_3}^-$</TEX> is higher than that of using electrolyte of containing <TEX>${NO_2}^-$</TEX>.
A nitrogen transformation model for multi-layer enhanced groundwater remediation technology (2017)

The multi-layer enhanced groundwater remediation technology (MET) is an innovative platform that integrates physical chemistry, bioremediation, and phytoremediation technology to safely and effectively remediate ammonia nitrogen in groundwater. A nitrogen transformation model was established to study the mechanism of nitrogen transformation within ammonia nitrogen removal in the MET. The model considered organic nitrogen, ammonia nitrogen, and nitrate nitrogen as the variables, and ammonification, nitrification, denitrification, microbial assimilation, plant absorption, adsorption-desorption, and volatilization as the influencing factors. The unknown parameters of the model were obtained by fitting the data from a bench-scale experiment, and the results of the model validation and comparison showed that under the experimental initial conditions (the hydraulic load of the influent is 14.68 m<sup>3</sup>/(m<sup>2</sup> d) and the concentration of the ammonia nitrogen is 25.0 mg/L) and after the device ran for 45d continuously, the simulated and measured average concentration values of ammonia nitrogen in the effluent were 1.701 mg/L and 1.775 m/L, respectively, and the relative deviation was 4.17%. The simulated and measured average concentration values of nitrate nitrogen in effluent were 11.474 mg/L and 11.244 m/L, respectively, and the relative deviation was 2.05%, and the total removal rate was 92.07%. Thus it can be seen that the predicted values of the nitrogen transformation model were in good agreement with the measured values, and the model could be applied to forecast the long-term remediation effects of nitrogen in groundwater by MET.
Structural Variations within the Transferrin Binding Site on Transferrin-binding Protein B, TbpB (2011)

Pathogenic bacteria acquire the essential element iron through specialized uptake pathways that are necessary in the iron-limiting environments of the host. Members of the Gram-negative Neisseriaceae and Pasteurellaceae families have adapted to acquire iron from the host iron binding glycoprotein, transferrin (Tf), through a receptor complex comprised of transferring-binding protein (Tbp) A and B. Because of the critical role they play in the host, these surface-exposed proteins are invariably present in clinical isolates and thus are considered prime vaccine targets. The specific interactions between TbpB and Tf are essential and ultimately might be exploited to create a broad-spectrum vaccine. In this study, we report the structure of TbpBs from two porcine pathogens, Actinobacillus pleuropneumoniae and suis. Paradoxically, despite a common Tf target, these swine related TbpBs show substantial sequence variation in their Tf-binding site. The TbpB structures, supported by docking simulations, surface plasmon resonance and hydrogen/deuterium exchange experiments with wild-type and mutant TbpBs, explain why there are structurally conserved elements within TbpB homologs despite major sequence variation that are required for binding Tf.
Murine Trefoil Factor 3 Does not Directly Modulate LPS‐Mediated Dendritic Cell Function (2007)

Peptides of the trefoil factor family (TFF) are expressed along the gastro-intestinal tract. They protect mucous epithelia from damage and contribute to mucosal repair, which is essential for preventing inflammation. Moreover, it has been suggested that TFF2 and TFF3, in particular, play a role in regulating immune responses. Depending on their activation status, dendritic cells (DC) can initiate either tolerance or immunity. This study, by comparing LPS-induced maturation of mTFF3-treated DC and non-treated DC, investigated whether murine TFF3 directly regulated DC function. mTFF3-treated DC and non-treated DC did not differ phenotypically or functionally. Both populations expressed, both before and after LPS-stimulation, similar levels of co-stimulatory molecules and cytokines, and were both efficient stimulators of T-cells. Our results suggest that mTFF3 does not govern immune responses on the level of DC function.
Power Utility Tests for Multi-MW High Energy Batteries (2018)

This paper reviews the procedures, layouts and metrics described in the new test manual issued by the Electric Power Research Institute (EPRI), in order to determine the performance and functionality of a utility scale battery energy storage system (BESS). In this approach, the large battery unit is connected to the dc-link of a bidirectional power conversion system (PCS), which may be interfaced with either the utility grid or a load bank for the purpose of estimating the BESS operation and performance characteristics, some of which includes; available charge/discharge energy at rated power, continuous charge/discharge duration, battery ramp rate, and ac round trip efficiency (RTE). The bidirectional converter is operated with different charge and discharge cycles relevant to each specification and the battery state of charge along with electrical measurements at the ac and dc side are monitored and recorded. Also, an electrical equivalent circuit for a utility scale battery unit was developed based on the 1MW/2MWh operational BESS at the LG &E and KU E.W. Brown facility. This model was formulated using an improved method for estimating the battery cell parameters.
Efficient Heat Shielding of Steel with Multilayer Nanocomposite Thin Film (2021)

In an effort to protect metal substrates from extreme heat, polymer-clay multilayer thin films are studied as expendable thermal barrier coatings. Nanocomposite films with a thickness ranging from 2 to 35 μm were deposited on steel plates and exposed to the flame from a butane torch. The 35 μm coating, composed of 14 deposited bilayers of tris(hydroxymethyl)aminomethane (THAM)-buffered polyethylenimine (PEI) and vermiculite clay (VMT), decreased the maximum temperature observed on the back side of a 0.32 cm thick steel plate by over 100 °C when heated with a butane torch. Upon exposure to high temperature, the polymer and amine salt undergo pyrolysis and intumesce, subsequently forming a char and blowing gas. The char encases the nanoclay platelets, and a ceramic bubble is formed. The macro-scale bubble, in tandem with the nanocomposite coating properties, increases resistance to heat transfer into the underlying metal substrate. This heat shielding behavior occurs through radiative effects and low aggregate through-plane conductivity resulting from multilayer nanodomains and intumesced porosity (i.e., conduction through the gas as the film expands to form a ceramic bubble). These relatively thin and lightweight films could be used to protect important metal parts (in automobiles, aircraft, etc.) from fire-related damage or other types of transient high-temperature situations.
An MPEG-2 video encoder LSI with scalability for HDTV based on three-layer cooperative architecture (1999)

Article An MPEG-2 video encoder LSI with scalability for HDTV based on three-layer cooperative architecture Share on Authors: Mitsuo Ikeda NTT Human Interface Laboratories, Japan NTT Human Interface Laboratories, JapanView Profile , Toshio Kondo NTT Human Interface Laboratories, Japan NTT Human Interface Laboratories, JapanView Profile , Koyo Nitta NTT Human Interface Laboratories, Japan NTT Human Interface Laboratories, JapanView Profile , Kazuhito Suguri NTT Human Interface Laboratories, Japan NTT Human Interface Laboratories, JapanView Profile , Takeshi Yoshitome NTT Human Interface Laboratories, Japan NTT Human Interface Laboratories, JapanView Profile , Toshihiro Minami NTT Human Interface Laboratories, Japan NTT Human Interface Laboratories, JapanView Profile , Jiro Naganuma NTT Human Interface Laboratories, Japan NTT Human Interface Laboratories, JapanView Profile , Takeshi Ogura NTT Human Interface Laboratories, Japan NTT Human Interface Laboratories, JapanView Profile Authors Info & Claims DATE '99: Proceedings of the conference on Design, automation and test in EuropeJanuary 1999 Pages 10–eshttps://doi.org/10.1145/307418.307445Published:01 January 1999 5citation203DownloadsMetricsTotal Citations5Total Downloads203Last 12 Months1Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Heterogeneous Effects of Calorie Content and Nutritional Components Underlie Dietary Influence on Pancreatic Cancer Susceptibility (2020)

Pancreatic cancer is a rare but fatal form of cancer, the fourth highest in absolute mortality. Known risk factors include obesity, diet, and type 2 diabetes; however, the low incidence rate and interconnection of these factors confound the isolation of individual effects. Here, we use epidemiological analysis of prospective human cohorts and parallel tracking of pancreatic cancer in mice to dissect the effects of obesity, diet, and diabetes on pancreatic cancer. Through longitudinal monitoring and multi-omics analysis in mice, we found distinct effects of protein, sugar, and fat dietary components, with dietary sugars increasing Mad2l1 expression and tumor proliferation. Using epidemiological approaches in humans, we find that dietary sugars give a MAD2L1 genotype-dependent increased susceptibility to pancreatic cancer. The translation of these results to a clinical setting could aid in the identification of the at-risk population for screening and potentially harness dietary modification as a therapeutic measure.
A Search Space Exploration Framework for e-Science Applications (2018)

High Performance Computing (HPC) has always been a fundamental component to conduct scientific experiments. Model calibrations/simulations often require several executions of scientific applications by changing their input parameters. This process is a common practice in research even though it represents a tedious and error-prone task. In this paper we propose Copper framework which employs a black-box strategy and contains a set of plugins to accelerate user experiments for exploring search spaces in HPC parametric applications. Copper has been used to conduct scientific experiments in different areas including, agriculture, oil gas, flood simulation, and bioinformatics.
Parametric analysis of LLC resonant converter using flat transformer for loss reduction (2010)

This paper presents the design of two flat transformers in LLC resonant converter. The trend toward high power density, high efficiency, and low profile in power supplies has exposed a number of limitations in the use of magnetic component structures. In the LLC resonant converter, the switching loss is reduced by soft-switching. Therefore, LLC resonant converter can be operated at high switching frequency with high efficiency. However, transformer loss becomes problems at high switching frequency. As a result, flat transformers temperature becomes high in proportion to the transformer loss. Therefore, it is necessary to reduce the transformer temperature by analyzing the loss. In this paper, design for reduction transformer temperature is presented.