gebhart/patrepeval huggingface dataset:
Sonochemical Synthesis of Mesoporous Iron Oxide and Accounts of Its Magnetic and Catalytic Properties (2002)

Synthesis of mesoporous iron oxides has been reported using a sonochemical technique. Iron(III) ethoxide was used as an inorganic precursor and CTAB as an organic structure directing agent. After sonication the surfactant was removed by calcination and solvent extraction methods. FTIR spectra demonstrated the removal of the surfactant from the pores of the mesoporous iron oxide. The calcinated material was characterized by XRD, TEM, TGA, and BET surface area measurements. The surface area after solvent extraction is found to be 274 m2/g. The magnetic and catalytic properties of the materials have been studied. The as-prepared amorphous Fe2O3 has shown a paramagnetic behavior, while after calcination at 350 °C it changes to γ-Fe2O3 with good magnetic properties. The catalytic activity of mesoporous iron oxide was studied in the reaction of cyclohexane oxidation under mild conditions. The mesoporous Fe2O3 catalyst has shown high conversion of cyclohexane into cyclohexanone and cyclohexanol, with a high selectivity.
An Efficient Strategy for the Synthesis of New Chiral and Prochiral Trisphosphines (1996)

The synthesis of a series of chiral and prochiral tris(diphenylphosphines) starting from (R,R)-tartaric acid or erythritol, respectively, is described. The new compounds based on a rigid 1,3-dioxolane ring may be useful as tridentate ligands for the complexation of several metals in different bonding modes.
Bidirectional Concentration-Dependent Effects of Tumor Necrosis Factor Alpha in Shigella dysenteriae -Related Seizures (2003)

We have previously demonstrated that pretreatment of mice with Shigella dysenteriae sonicate enhanced their susceptibility to pentylenetetrazole-induced seizures and that tumor necrosis factor alpha (TNF-alpha) was proconvulsive in this respect. The present study shows that TNF-alpha, at high concentrations, may also exert a suppressive effect on Shigella-mediated seizures. This implies that high levels of TNF-alpha may play a protective role in neurologic complications of S. dysenteriae infection.
A New Model for Transitioning Students from the Undergraduate Teaching Laboratory to the Research Laboratory. The Evolution of an Intermediate Organic Synthesis Laboratory Course (2006)

This article outlines the recent transformation of an intermediate undergraduate organic synthesis laboratory course at the University of Wisconsin–Madison. This course has had a unique design for over 30 years, with structured experiments performed in the teaching laboratory only for the first half of the course. In the second half of the course, students are assigned to projects in graduate research laboratories. The classroom component of the course, however, did not provide students with many of the skills essential for success in the research laboratory. Over the academic years 2003–2005, we systematically changed the classroom and laboratory components of this course so that it now provides experience using modern chemistry experimental techniques and chemical information resources, instruction in scientific writing and the use of chemical drawing software, and awareness of basic scientific ethics. Here, we outline our rationale behind each course component change, describe how the changes were implemented, and discuss how the effects on student learning were assessed. Overall, these changes have been greeted with enthusiasm by our students, faculty, and staff, and we believe this course provides a curricular model exportable to other chemistry departments.
Realtime MR guided endomyocardial biopsy with an active visualization bioptome (2015)

Background Invasive endomyocardial biopsy is an important tool to diagnose cardiomyopathy. But the diagnostic yield is low because the procedure is performed ‘blind’ using, particularly in processes characterized by heterogeneous myocardial involvement. MRI tissue characterization techniques, using late gadolinium enhancement or T1 mapping for example, can identify affected regions and guide biopsy. We performed realtime MR guided transcatheter endomyocardial biopsy using a novel active visualization MR conditional bioptome in swine.
<title>Chromosome mechanics in vivo: quantitative analysis of nonrigid 3D chromosome motion in Drosophila embryos</title> (1996)

Chromosomes are often arranged into specific configurations. One example is the metaphase plate of the Drosophila embryo in which chromosomes are arranged into a parallel bundle. How is this configuration established and maintained? Quantitative analysis of chromosomes motion in vivo should help answer this question by providing a measure of the relevant mechanical properties of the chromosomes themselves. In addition, motion analysis will allow us to study interactions of chromosomes with the mitotic spindle. In order to analyze moving mitotic chromosomes, we acquire time-lapse 3D images of chromosomes in living Drosophila embryos, and then interactively model the chromosome configuration at each time point. A model-based motion estimation algorithm is then applied. From the motion estimate, we can visualize trajectories of different regions on the chromosomes, such as centromeres and telomeres, during metaphase and during prometaphase congression. In addition, quantitative estimates of mechanical properties such as mobility and flexibility can be computed. In this preliminary report we describe computational tools for tracking and visualizing 3D chromosome motion, and for detecting oscillations in position along the mitotic spindle.
Glucose-Stimulated Genes and Prospects of Gene Therapy for Type I Diabetes (1997)

I. Introduction II. Transcriptional Regulation of Glucose-Responsive Genes A. The insulin gene 1. Glucose-signaling pathway in pancreas β-cells 2. E elements of the insulin gene promoter 3. A elements of the insulin gene promoter 4. Role of the E and A boxes of the insulin gene promoters in glucose-dependent transcriptional regulation 5. Role of the cAMP pathway in glucose responsiveness of the insulin gene promoters B. Transcriptional regulation of glucose-responsive genes in the liver 1. The general outlook for glucose metabolism in the liver 2. Transcriptional glucose signaling mechanisms in the liver 3. Glucose/carbohydrate response elements III. Cell and Gene Therapies for IDDM A. Islet and cell transplantations 1. Transplantation of islets 2. Transplantation of established lines B. Bioartificial pancreas C. Transplantation of genetically engineered cells 1. The “ideal” engineered cell for glucose-dependent insulin secretion 2. Engineering established neuroendocrine cells 3. Engineering endogenous he...
Supplementary Table S3 from Molecular Analysis of Plasma DNA for the Early Detection of Lung Cancer by Quantitative Methylation-Specific PCR (2023)

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Sound emissions by a laboratory bubble cloud (1994)

This paper presents the results obtained from a detailed study of the sound field within and around a cylindrical column of bubbles generated at the center of an experimental water tank. The bubbles were produced by forcing air through a circular array of hypodermic needles. As they separated from the needles the ‘‘birthing wails’’ produced were found to excite the column into normal modes of oscillation whose spatial pressure-amplitude distribution could be tracked in the vertical and horizontal directions. The frequencies of vibration were predicted from theoretical calculations based on a collective oscillation model and showed close agreement with the experimentally measured values. On the basis of a model of the column excitation, absolute sound levels were analytically calculated with results again in agreement with the measured values. These findings provide considerable new evidence to support the notion that bubble plumes can be a major source of underwater sound around frequencies of a few hundred hertz.
Coverage Study of ATSC 3.0 Under Strong Co-Channel Interference Environments (2018)

In addition to the traditional TDM/FDM, the advanced television systems committee (ATSC) 3.0 next generation digital TV standard has adopted state-of-the-art coding and modulation, as well as the new layered division multiplexing (LDM) technology. The ATSC 3.0 system is able to provide higher data throughput, more robust reception, better spectrum efficiency, and flexible service combinations in one RF channel with different robustness and reception conditions. Due to the adoption of a two-layer LDM, the coverage for ATSC 3.0 is very different from the legacy one-transmitter-one-coverage ATSC 1.0 system. With the new enabling technologies, the ATSC 3.0 can greatly increase the coverage/service areas, reduce the distance between co-channel assignments, and introduce local program insertion and targeted advertisement. This paper addresses the ATSC 3.0 coverage and co-channel interference issues, by using the two-layer LDM technology with different operating parameters. Simulations demonstrate that, similar to the 4G long term evolution, the ATSC 3.0 co-channel assignment could be reduced to two times the service coverage radius. This means an improvement of the spectrum efficiency by up to four times in comparison with today's system. It is also proved through simulations that significant TV program gains can be obtained with this new system. The deployment of single frequency networks can further improve the coverage and reduce the interference.
FP167ADVERSE EVENTS WITH GLUCOCORTICOID STANDARD OF CARE VERSUS AVACOPAN IN ANCA-ASSOCIATED VASCULITIS: OBSERVATIONS FROM THE CLEAR TRIAL (2018)

INTRODUCTION AND AIMS: Renal thrombotic microangiopathy (TMA) is an uncommon pathological finding in lupus nephritis (LN), and its clinical significance remains to be established.
Synthesis of metallocene catalysts supported on poly[p-(silylene)phenylene] derivatives for the application to olefin polymerizations (1999)

The polymeric [Ind2Si(C6H4)]n and [Ind2Si(C6H4)2]m compounds (Ind = indenyl) were synthesized via the condensation reaction of bisindenyldichlorosilane and p-dilithiobenzene or p-dilithiobiphenyl, and the supported-type zirconocene catalysts were prepared by reacting them with zirconium tetrachloride. The content of zirconium in the catalysts is much higher than that in the metallocene catalysts supported by inorganic compounds. Polymerizations of ethene and propene were conducted with them using methylaluminoxane (MAO) or ordinary alkylaluminiums as cocatalysts and toluene as the solvent. The catalysts combined with MAO display very high activities especially for the ethene polymerization. From the polymerization at high temperatures, it was found that the active species are markedly stabilized, probably due to the rigid backbones of the carriers. The activity of the catalysts activated with ordinary alkylaluminiums is far less as compared with those activated with MAO.
Domain-Wall Induced Coupling between Ferromagnetic Layers (2000)

The remanent magnetization of a hard ferromagnetic CoPtCr layer is progressively decreased by repeated switching of a neighboring soft magnetic layer. We show that this effect depends strongly on the thickness of the CoPtCr layer and the spacing between the hard and soft layers. We propose a model that accounts for these results: An interlayer magnetostatic coupling is induced by large stray fields from domain walls that form within the soft layer during its magnetization reversal.
Nanocatalysts for the Heck Coupling Reactions (2013)

The Heck coupling reaction can be catalyzed by two different types of catalytic systems, namely homogeneous catalysts or heterogeneous catalysts, which include nanocatalysts. This chapter describes some of the synthetic methods employed to make Pd catalysts. It discusses the advantages and disadvantages of the homogeneous and heterogeneous catalysts used for the Heck reaction. The chapter explains the Heck reaction catalyzed by transition metal nanoparticles, mainly Pd-nanoparticles (NPs). Core—shell nanostructures composed of polymers were used for the synthesis of heterogeneous catalysts for the Heck reaction. Mesoporous material-based heterogeneous catalysts for the Heck reaction are most commonly synthesized by immobilizing organopalladium complexes or palladium nanoparticles within the pores of organic-functionalized mesoporous materials. The chapter also deals with polymeric-based nanocatalysts for the Heck coupling reactions and carbon nanomaterial-supported Heck coupling reactions.
Second Generation Synthesis of C27−C35 Building Block of E7389, a Synthetic Halichondrin Analogue (2009)

A practical method is reported to synthesize E7389 C27-C35 building block 13 from 1,2-O-isopropylidene-alpha-D-5-deoxyglucurono-6,3-lactone (3). This synthesis relies on two key processes: (1) C34/C35-diol is introduced via asymmetric dihydroxylation with dr = 3:1, with the undesired C34-diastereomer effectively removed by crystallization of 11, and (2) the C30 PhSO2CH2 group is introduced stereoselectively (>100:1) via hydrogenation of 12 in the presence of the Crabtree catalyst. The reported synthesis is practically free from chromatographic separation.
Dual-etch apodised grating couplers for efficient fibre-chip coupling near 1310 nm wavelength (2017)

We present our recent work on fibre-chip grating couplers operating around 1310 nm. For the first time, we demonstrate the combination of dual-etch and apodization design approaches which may achieve a coupling efficiency of 85% (-0.7 dB). Subwavelength structures were employed to modify the coupling strength of the grating. -1.9 dB efficiency was measured from a first set of fabricated structures.
Use of Magnetic Resonance Imaging to Measure Facial Soft Tissue Depth (2006)

Magnetic resonance images can be used to estimate tissue depth in human faces with precision.
Development of an Optrode for Intramural Multisite Optical Recordings of Vm in the Heart (2003)

These data demonstrate feasibility of multisite transmural measurements of Vm without signal averaging and ratiometry. This technique might become useful in studies of transmural impulse conduction during arrhythmias and defibrillation.
A two‐step approach to depth migration of low frequency electromagnetic data (2005)

In order to migrate electromagnetic data from a low frequency controlled source, 3D electromagnetic Green functions should be used since the near‐field effects may be large. Imaging principles of the correlation type do not have sufficient depth sensitivity to be used in a one‐pass migration step. Depth sensitivity is increased if a non‐local operator is introduced in the imaging condition. This operator accounts for the lateral propagation of the EM field in the high resistivity reservoir. The non‐local operator depends on two parameters related to the resistivity and thickness of an assumed resistivity anomaly. These parameters can be estimated from a limited set of forward modeling operations.
The influence of cast shadows on “Deliciousness” perception in cakes (2019)

Food images contain several visual elements, such as lightning, color, shapes, shadows, etc. While the influence of the mentioned above have been well studied, the influence of shadows on “Deliciousness” impression of food remains unexplored. Thus, this study investigated how does the strength of the cast shadow and the angle of the light source influence deliciousness perception. There were 38 participants which evaluated 4 experimental conditions regarding the strength of the cast shadow, and 3 experimental conditions regarding the angle of the light source. A total of 12 images were evaluated with the conditions described. In each condition, the participants rated how delicious they perceived the visual stimuli. The results showed that the cast shadows acts as a diminisher of the light, and that high lightning angles images rated better than the other light angle conditions when the presence of shadows is null or close to null.
Quantitative determination of ergothioneine in plasma and tissues by TLC-densitometry. (1980)

A rapid and reliable thin-layer chromatographic (TLC) method for the quantitative analysis of ergothioneine in plasma and in various organs is presented. After extraction from biological materials with acetone/methanol (1 : 1), ergothioneine was separated by TLC and the spot corresponding to the compound with Rf 0.29 was quantified by scanning with a densitometer at 256 nm. The sensitivity of the assay was 0.05 μg/20μl of liver extract. This procedure should be useful in pharmacokinetic studies of ergothioneine in relation to its physiological role.
Gene Therapy: Charting a Future Course—Summary of a National Institutes of Health Workshop, April 12, 2013 (2020)

Recently, the gene therapy field has begun to experience clinical successes in a number of different diseases using various approaches and vectors. The workshop Gene Therapy: Charting a Future Course, sponsored by the National Institutes of Health (NIH) Office of Biotechnology Activities, brought together early and mid-career researchers to discuss the key scientific challenges and opportunities, ethical and communication issues, and NIH and foundation resources available to facilitate further clinical advances.
Nanocomposite Counter Electrode Materials for Electrochromic Windows (2010)

Nickel–oxide–based nanocomposite films were deposited using radio-frequency magnetron sputtering from ceramic targets composed of lithium, nickel, and tungsten oxides. The resulting films are partially prelithiated and exhibit a slight spectral shift relative to tungsten-free films when colored. Electron microscopy and X-ray diffraction show that the films are composed of nanocrystallites with NiO structure. The films show promise as electrochromic counter electrode layers that are durable, efficient, and fabricated using a scalable, economical process.
Amplitude analysis ofB+→J/ψϕK+decays (2017)

The first full amplitude analysis of
In vivo studies of low level laser (light) therapy for traumatic brain injury (2012)

Low-level laser (or light) therapy (LLLT) is attracting growing interest to treat both stroke and traumatic brain injury (TBI). The fact that near-infrared light can penetrate into the brain allows non-invasive treatment to be carried out with a low likelihood of treatment-related adverse events. It is proposed that red and NIR light is absorbed by chromophores in the mitochondria of cells leading to changes in gene transcription and upregulation of proteins involved in cell survival, antioxidant production, collagen synthesis, reduction of chronic inflammation and cell migration and proliferation. We developed a mouse model of controlled cortical impact (CCI) TBI and examined the effect of 0, 1, 3, and 14 daily 810-nm CW laser treatments in the CCI model as measured by neurological severity score and wire grip and motion test. 1 laser Tx gave a significant improvement while 3 laser Tx was even better. Surprisingly 14 laser Tx was no better than no treatment. Histological studies at necropsy suggested that the neurodegeneration was reduced at 14 days and that the cortical lesion was repaired by BrdU+ve neural progenitor (stem) cells at 28 days. Transcranial laser therapy is a promising treatment for acute (and chronic TBI) and the lack of side-effects and paucity of alternative treatments encourages early clinical trials.
New routes to Cu‐patterned teflon substrates (1992)

In microelectronics, copper conductors and Teflon substrates are the materials of choice in many applications due to the high conductivity of copper and the low dielectric constant of Teflon. The nature of Teflon, however, results in low adhesion strength, which makes a multi‐step Cu‐deposition process necessary. Here, an alternative, selective CVD, which can produce smaller feature sizes and reduces the need for wet etching, is presented and explained.
Low threshold 1.55 µm Quantum dash microring lasers (2019)

We report the first room-temperature-continuous-wave (CW) operation of electrically-injected InAs quantum-dash microring lasers emitting at 1.55 µm telecom window. The microrings sustain CW lasing up to 55°C, while the lowest threshold current density is 528A/cm2.
Fractionation and analysis of gamma irradiated lysozyme (1970)

The chemical and conformation properties of whole and fractionated lysozyme irradiated in the dry solid state by Cesium-137 gamma rays have been studied by a variety of procedures.
Rearrangement and junctional-site sequence analyses of T-cell receptor gamma genes in intestinal intraepithelial lymphocytes from murine athymic chimeras. (1991)

The molecular organization of rearranged T-cell receptor (TCR) gamma genes intraepithelial lymphocytes (IEL) was studied in athymic radiation chimeras and was compared with the organization of gamma gene rearrangements in IEL from thymus-bearing animals by polymerase chain reaction and by sequence analyses of DNA spanning the junction of the variable (V) and joining (J) genes. In both thymus-bearing mice and athymic chimeras, IEL V-J gamma-gene rearrangements occurred for V gamma 1.2, V gamma 2, and V gamma 5 but not for V gamma 3 or V gamma 4. Sequence analyses of cloned V-J polymerase chain reaction-amplified products indicated that in both thymus-bearing mice and athymic chimeras, rearrangement of V gamma 1.2 and V gamma 5 resulted in in-frame as well as out-of-frame genes, whereas nearly all V gamma 2 rearrangements were out of frame from either type of animal. V-segment nucleotide removal occurred in most V gamma 1.2, V gamma 2, and V gamma 5 rearrangements; J-segment nucleotide removal was common in V gamma 1.2 but not in V gamma 2 or V gamma 5 rearrangements. N-segment nucleotide insertions were present in V gamma 1.2, V gamma 2, and V gamma 5 IEL rearrangements in both thymus-bearing mice and athymic chimeras, resulting in a predominant in-frame sequence for V gamma 5 and a predominant out-of-frame sequence for V gamma 2 genes. These findings demonstrate that (i) TCR gamma-gene rearrangement occurs extrathymically in IEL, (ii) rearrangements of TCR gamma genes involve the same V gene regardless of thymus influence; and (iii) the thymus does not determine the degree to which functional or nonfunctional rearrangements occur in IEL.
Magnetic Interaction Observed in the Polyacetylenic Derivatives with High Spin Concentration (1990)

Abstract Electronic state and magnetic interaction of π-conjugated phenoxy radicals bearing a polyacetylenic backborn are described. Poly(3,5-di-t-butyl-4-hydroxyphenylacetylene) (7a) and poly(p-ethynyl-phenylhydrogalvinoxyl) (8a) with molecular weight ca. 104 are characterized. ESR spectra with hyperfine structure for the chemically oxidized 7b indicate that the phenoxy radical conjugates through the polyacetylenic main chain over ca. 7 monomer units as a “neutral soliton.” Polyradicals 7b and 8b are surprisingly stable even in the solid state, because of a resonance stabilization and/or a steric effect of the conjugated main chain. An antiferromagnetic interaction is observed for 7b with spin concentration above 10 mol%. Mechanism of the magnetic interaction is discussed.
SPUTNIK: an R package for filtering of spatially related peaks in mass spectrometry imaging data (2018)

Supplementary data are available at Bioinformatics online.