gebhart/patrepeval huggingface dataset:
Appropriateness of Diagnostic Management and Outcomes of Suspected Pulmonary Embolism (2006)

Diagnostic management that does not adhere to guidelines is frequent and harmful in patients with suspected pulmonary embolism. Several risk factors for inappropriateness constitute useful findings for subsequent interventions.
Selection of Phototransduction Genes inHomo sapiens (2013)

There is evidence for selective pressure in the genes involved in retinal phototransduction, and traces of this selective pressure can be demonstrated using SNP-level and gene-level metrics of allelic variation. We hypothesize that the selective pressure on these genes was related to their role in low light vision and retinal adaptation to ambient light changes. Uncovering the underlying genetics of evolutionary adaptations in phototransduction not only allows greater understanding of vision and visual diseases, but also the development of patient-specific diagnostic and intervention strategies.
A Fast Diagnostic to Inform Screening of Discarded or Retired Batteries (2022)

With the increased pervasiveness of Lithium-ion batteries, there is growing concern for the amount of retired batteries that will be entering the waste stream. Although these batteries no longer meet the demands of their first application, many still have a significant portion of their initial capacity remaining for use in secondary applications. Yet, direct repurposing is generally not possible and each cell in a battery must be evaluated, increasing the cost of the repurposed packs due to the time intensive screening process. In this paper, a rapid assessment of the internal resistance of a cell is proposed. First, this method of measuring the resistance is completed on cells from twelve retired battery packs and one fresh pack using a hybrid pulse power characterization (HPPC) test as a benchmark for the analysis. Results from these tests show relatively constant resistance measurements across mid to high terminal voltages, allowing this metric to be independent of state of charge (SOC). Then, the relation between internal resistance and capacity across the various packs is discussed. Initial experimental results from this study show a correlation between internal resistance and capacity which can be approximated with a linear fit, suggesting internal resistance measurements taken above a threshold cell terminal voltage may be a suitable initial screening metric for the capacity of retired cells without knowledge of the SOC.
Overview of the Protected Disclosure Provisions and Related Protections (2022)

Abstract This chapter explains the aims of the legislation covering whistleblowing. The scheme is set out, with the key definitions of qualifying and protected disclosures. A flowchart is provided which shows the routes to protection through three tiers of disclosure, depending on the recipient of the disclosure: a first tier, essentially to the employer or other person thought to be accountable for the matter which concerns the worker; a second tier to an appropriate regulator; and a third tier for wider disclosures. The chapter describes the means by which protection is provided: the right to be protected against ‘detriment’ and the right not to be unfairly dismissed. The case law showing the courts’ purposive approach to construction of whistleblowing protection is also discussed. Other protections which may complement protection under the protected disclosure scheme are compared and contrasted: those for employees and workers in relation to health and safety at work activities, for employees who assert a statutory right, and for those who do protected acts under the Equality Act.
Ellipsometric measurement of particle-spiked wafer surfaces (2015)

We studied an ability of ellipsometry for quantitative evaluation of particle contamination. Very good correlation between the ellipsometric measurement and the bead amount was confirmed. This technique can be employed for quick evaluation of wafer cleaning at laboratories.
The Reactions of Coordinated Ligands (1962)

The ligands NH2CH2CH2SH, CH3N(CH2CH2SH)2, and HSCH2CH2N=C(CH3)C(CH3)=NCH2CH2SH have been studied. The first forms monomeric complexes, [Ni(NH2CH2CH2S)2] and [Co(NH2CH2CH2S)3], and trimeric complex cations, [M{M'(NH2CH2CH2S)2}2]n+ and [M{M'(NH2CH2CH2S)3}2]n+. The second ligand readily forms neutral dimeric complexes of the form [M2{CH3N(CH2CH2S)2}2]. The tetradentate ligand forms monomeric square planar complexes. Synthetic and kinetic studies reveal that the coordinated mercapto group may be converted into the coordinated thioether function without breaking the metal-sulfur bond. The nucleophilic power of the coordinated mercapto group exceeds that of RSH, but depends on the metal atom. Bridging protects the sulfur atom from alkylation. In the case of nickel(II), alkylation is accompanied by expansion of the coordination number of the nickel from 4 to 6. Ligand reactions have led to the synthesis of planar ligands completely cyclized about the metal ion.
ISOLATION OF ROTAVIRUS FROM FOALS WITH DIARRHOEA (1978)

A rotavirus, morphologically similar to other known rotaviruses, was demonstrated in the faeces of 5 foals with diarrhoea on two properties. Four of these 5 samples produced specific intracytoplasmic fluorescence in cell culture when reacted with calf rotavirus antiserum conjugate. Sixteen affected foals from both properties were depressed, did not suckle and became recumbent. Most had a watery diarrhoea which lasted for 3 days and resulted in some dehydration and loss of body condition. Sick foals were separated from their mothers following the onset of diarrhoea and given fluid therapy and antibiotics, but despite these measures 4 of 12 affected foals on one property died. Acute and convalescent sera were collected from 6 foals, and in each case a rise in the titres of complement fixing and neutralising antibodies was demonstrated. Faecal filtrates containing foal rotaviruses were fed to gnotobiotic piglets and the effects compared with those of other rotaviruses. Viral isolates from both properties produced an asymptomatic infection in piglets. This contrasts with the other rotaviruses isolated in Australia that have been shown to cause diarrhoea in gnotobiotic piglets.
Author Correction: Tailings facility disclosures reveal stability risks (2021)

An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Single-cell transcriptomics of the aged mouse brain reveals convergent, divergent and unique aging signatures (2018)

The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, but exactly how the brain is affected with aging remains largely unknown. Here we performed a single-cell transcriptomic analysis of young and old mouse brains. We provide a comprehensive dataset of aging-related genes, pathways and ligand-receptor interactions in nearly all brain cell types. Our analysis identified gene signatures that vary in a coordinated manner across cell types and gene sets that are regulated in a cell type specific manner, even at times in opposite directions. Thus, our data reveals that aging, rather than inducing a universal program drives a distinct transcriptional course in each cell population. These data provide an important resource for the aging community and highlight key molecular processes, including ribosomal biogenesis, underlying aging. We believe that this large-scale dataset, which is publicly accessible online ( aging-mouse-brain ), will facilitate additional discoveries directed towards understanding and modifying the aging process.
Oxoiron(IV) in Chloroperoxidase Compound II Is Basic: Implications for P450 Chemistry (2004)

With the use of x-ray absorption spectroscopy, we have found that the Fe-O bond in chloroperoxidase compound II (CPO-II) is much longer than expected for an oxoiron(IV) (ferryl) unit; notably, the experimentally determined bond length of 1.82(1) A accords closely with density functional calculations on a protonated ferryl (Fe(IV)-OH, 1.81 A). The basicity of the CPO-II ferryl [pKa > 8.2 (where Ka is the acid dissociation constant)] is attributable to strong electron donation by the axial thiolate. We suggest that the CPO-II protonated ferryl is a good model for the rebound intermediate in the P450 oxygenation cycle;with elevated pKa values after one-electron reduction, thiolate-ligated ferryl radicals are competent to oxygenate saturated hydrocarbons at potentials that can be tolerated by folded polypeptide hosts.
In vitro activity of N-chlorotaurine (NCT) in combination with NH4Cl against Trichomonas vaginalis (2010)

Trichomoniasis, caused by the protozoan Trichomonas vaginalis, is usually treated with metronidazole, however resistance is on the rise. In this study, N-chlorotaurine (NCT), a new endogenous mild active chlorine compound for topical use, killed T. vaginalis in vitro within 15 min of treatment at a concentration of 55 mM (1%), which is well tolerated by human tissue. The activity of NCT was further enhanced by addition of ammonium chloride (NH(4)Cl). A combination of 5.5 mM (0.1%) NCT plus 19 mM (0.1%) NH(4)Cl killed 100% of trichomonads within 5 min.
Combinatorial Development of Biomaterials for Clonal Growth of Human Pluripotent Stem Cells (2010)

July 3, 2012
Physical modelling and design of thin film SOI lateral PIN photodiodes for blue DVD-applications (2005)

In this article, performances and design of thin-film SOI photodiodes have been investigated in terms of speed, dark current and sensitivity. Speed performances may make such diodes, the only suitable low cost integrated photodetectors for fast optical storage and communication systems. Their advantage in term of dark leakage currents also allows low noise and low offset performances. A 4 to 5 /spl mu/m intrinsic length PIN diodes in a 0.12 /spl mu/m SOI technology appear highly suitable for blue DVD applications.
Stereoselective aldol condensation. Use of chiral boron enolates (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStereoselective aldol condensation. Use of chiral boron enolatesSatoru Masamune, William Choy, Kerdesky Francis A. J., and Barbara ImperialiCite this: J. Am. Chem. Soc. 1981, 103, 6, 1566–1568Publication Date (Print):March 1, 1981Publication History Published online1 May 2002Published inissue 1 March 1981https://pubs.acs.org/doi/10.1021/ja00396a050https://doi.org/10.1021/ja00396a050research-articleACS PublicationsRequest reuse permissionsArticle Views2633Altmetric-Citations204LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A MnOx–graphitic carbon composite from CO2 for sustainable Li-ion battery anodes (2022)

Molten salt CO 2 capture and electrochemical transformation (MSCC-ET) has been proposed as a sustainable synthetic method for Mn nanocrystalline inclusions in a graphitic matrix, which paves the way to new methods to produce composite materials.
Policy enabled caching for distributed AI (2017)

Web Caching has established itself as a key enabling technology within the Internet. It enables efficient browsing of websites and web-based services on networks that are bandwidth constrained. However, similar techniques are not available for AI based solutions. Many AI solutions are based on deep neural networks or similar approaches which require creation of machine learning models trained with huge amounts of data. Such models are best created in centralized locations with significant processing power. In many environments, sending the data to a centralized location is infeasible or undesirable. A judicious combination of ideas borrowed from web-caching paradigm, with ideas from AI and machine learning can provide an effective solution for exploitation of deep learning models in bandwidth constrained environments. Allowing such caches to generate their own policies using a generative policy approach can enable the creation of a generic edge caching system which can be used with a wide variety of backend AI systems.
Response to programmed ventricular stimulation and clinical outcome in cardiac arrest survivors receiving randomised assignment to implantable cardioverter defibrillator or antiarrhythmic drug therapy (2004)

In CA survivors, inducibility at baseline PVS is independently associated with an increased risk of all-cause death, but not SD. In addition, response to PVS may help to identify subgroups of patients who could most benefit from ICD.
Modular multiple dispatch with multiple inheritance (2007)

Overloaded functions and methods with multiple dispatch are useful for extending the functionality of existing classes in an object-oriented language. However, such functions introduce the possibility of ambiguous calls that cannot be resolved at run time, and modular static checking that such ambiguity does not exist has proved elusive in the presence of multiple implementation inheritance. We present a core language for defining overloaded functions and methods that supports multiple dispatch and multiple inheritance, together with a set of restrictions on these definitions that can be statically and modularly checked. We have proved that these restrictions guarantee that no undefined nor ambiguous calls occur at run time, while still permitting various kinds of overloading.
ChemInform Abstract: Neurochemistry of Aging. Part 2. Design, Synthesis, and Biological Evaluation of Halomethyl Analogues of Choline with High Affinity Choline Transport Inhibitory Activity. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
SYNTHÈSE DE MANNOSE 6-PHOSPHONATES, ANALOGUES ISOSTÈRES DU MANNOSE 6-PHOSPHATE (2000)

Abstract Nous décrivons la syntèse de deux phosphonates analogues isostères du Mannose 6-Phosphate (M6P). Ce dernier est un marqueur de reconnaissance pré dans la structure des enzymes lysosomales et est indispensable à leur transport vers les lysosomes. Le phosphonate 1 bioisostère du M6P a été obtenu par une méthode de préparation impliquant I'utilisation du groupement triméthylsilyle comme groupe protecteur des fonctions alcool secondaire du mannose. Seule cette voie de synthèse a permis I'obtention du mannosylphosphonate 2 fonctionnalisé en position anomérique par un groupement paraaminophényle qui est couramment utilisé pour former des liens avec des protéines ou d'autres substrats présentant un intérét biologique. The synthesis of two isosteric phosphonate analogs of the M6P recognition marker, present in the lysosomal enzyme structure, is described. The phosphonate 1, a bioisosteric analog of the M6P was obtained via a multistep synthesis using the trimethylsilyl protective group. Only this method allowed the obtention of the mannosylphosphonate 2, functionalized in the anomeric position by a paraaminophenyl group which is commonly use to link proteins or other substrates of biological interest.
A Fluorophore‐Based Bio‐Barcode Amplification Assay for Proteins (2005)

A fluorophore-based bio-barcode amplification assay that relies on in situ detection of fluorophore-labeled barcodes attached to polystyrene (PS) microparticles rather than to gold nanoparticles has been developed; the method involves significantly fewer experimental steps and, thus, reduces the time for the assay without losing its ultrahigh sensitivity. The fluorescence image shows PS particles, on which barcode DNA strands labeled with a fluorophore dye (Alexa 647) have been hybridized with the barcode DNA capture strands.
Risks of Oral Anticoagulant Therapy With Increasing Age (2005)

The incidence of both bleeding and thromboembolic events increases sharply with advanced age. Because higher thromboembolic risk with age often makes it unfeasible to withhold oral anticoagulation from elderly patients, future studies should focus on ways to lower the bleeding risk.
Butadiene Polymers (2002)

Abstract This article provides an overview of polybutadiene materials as a progression from the monomer 1,3‐butadiene to a useful polymer product with a wide range of applications. A brief history of polybutadiene, with its development as a high cis ‐polybutadiene material during World War I through its present day use as a high vinyl substitute for styrene–butadiene rubber is included. The structure and properties of the monomer are presented, along with monomer manufacture, typical specifications, and health and safety issues. Following a detailed discussion on both polymer microstructure and macrostructure, there is an in‐depth review of polymerization methods that are typically used to produce polybutadiene. The state‐of‐the‐art in free‐radical, Ziegler–Natta, anionic, and cationic polymerization techniques that produce polybutadiene are thoroughly discussed in terms of the influence of catalyst/initiator technology on microstructure and the resulting relationship between microstructure and applications. The most popular commercial polymerization processes are also reviewed including solution, emulsion, and an introduction to gas‐phase polybutadiene polymerization technology. Finally, the economic aspects of polybutadiene materials are presented, including major producers, capacities, and pricing.
Withdrawal: Alternative Oxidants for the Catalytic Oxidative Coupling of Methane (2020)

The above article, published online on 26 August 2020 in Wiley Online Library (wileyonlinelibrary.com), has been withdrawn by agreement between the authors, the journal's interim Editor-in-Chief Committee, and Wiley-VCH GmbH, Weinheim. The withdrawal has been agreed due to an error at the publishers, which led to the upload of the manuscript before completion of the peer review process.
Production of extracts from olive by-products and evaluation of their cytotoxic/cytostatic activity (2012)

Over the years, several studies have related olive to a low incidence of several diseases, including cancer. This may be due to the phenolic compounds encountered in olive products. Recent studies have shown that the wastes produced during olive processing are valuable sources of phenols. In the present work, extracts were obtained from various by-products generated during olive processing, specifically: olive fruit debittering, olive oil mill waste, olive paste and olive leaves, and were chemically characterized. Furthermore, their cytotoxic/cytostatic effects were evaluated against a panel of various cancer cell lines as determined by MTT assays. Our results show that these extracts are rich in phenolic compounds, mainly oleuropein 1 and its degradation molecule hydroxytyrosol 2, and exhibit promising biological activities.
Studies in the steroid group. Part LXXXII. The preparation of nine mono- and eight di-oxoandrostanes, 5α-estran-17-one, and 5α-pregnane-2,20-dione (1972)

The following steroids, required as substrates for microbiological studies, have been prepared: 17α-hydroxy-2-oxo-, 7α-hydroxy-3-oxo-, 7β-hydroxy-3-oxo-,17β-hydroxy-7-oxo-, and 3β-acetyl-5α-androstane, 6β-hydroxyandrost-4-en-3-one, androst-5-en-7-one, 6β-hydroxy-3-oxo- and 6-oxo-5β-androstane, 2,7-, 3,6-, 3,7-, 3,12-, 7,17-, and 11,16-dioxo-5α-androstane, 3β-acetyl-17-oxo-5α-androstane, 5α-estran-17-one, and 5α-pregnane-2,20-dione. This work makes some diketones of the less common types available in reasonable quantity.
Säurekatalysierte Alkin/Alken‐Kupplung an ReIII‐Zentren (1988)

Als nützliches Zwischenprodukt für Organorheniumkomplexe erwies sich der aus dem Tetrachlorid 1 herstellbare Alkinkomplex 2 . In Gegenwart katalytischer Mengen HBF 4 konnte 2 in Toluol mit Ethylen und 2‐Buten zu den 1,3‐Dienkomplexen 3 bzw. 4 umgesetzt werden. Mit 2‐Butin und Acetonitril findet in Gegenwart äquimolarer HBF 4 ‐Mengen ein Cl/Ligand‐Austausch, aber keine CC‐Kupplung statt. magnified image
OSCAR (2016)

The design of an adaptive video client for mobile users is challenged by the frequent changes in operating conditions. Such conditions present a seemingly insurmountable challenge to adaptation algorithms, which may fail to find a balance between video rate, stalls, and rate-switching. In an effort to achieve the ideal balance, we design OSCAR, a novel adaptive streaming algorithm whose adaptation decisions are optimized to avoid stalls while maintaining high video quality. Our performance evaluation, using real video and channel traces from both 3G and 4G networks, shows that OSCAR achieves the highest percentage of stall-free sessions while maintaining a high quality video in comparison to the state-of-the-art algorithms.
[Perinatal policy in cases of extreme prematurity; an investigation into the implementation of the guidelines]. (2013)

The recommendations from these guidelines have been implemented swiftly in Dutch perinatal centres, and survival of extremely preterm infants has increased. This has imposed a considerable burden on the capacity of these centres. Little is yet known about the long-term (up to school-age) health and survival of these infants.
Protein adsorption to monosodium urate crystals: differential responses of human peripheral blood neutrophils. [Etiology of acute gouty arthritis] (1976)

In order for acute gouty arthritis to occur, neutrophils must interact with monosodium urate (MSU) crystals. As a result of this interaction, enzymes, chemotactic factors, and other mediators of the inflammatory response are released from neutrophil lysosomes. It was observed that MSU crystals adsorb gamma globulin, albumin, and other proteins found in serum and joint fluid. Results are reported from a study designed to demonstrate the effects of coating of MSU crystals with proteins on the phlogistic responses of neutrophils to crystals.
Effects of Annealing Temperature on Electrical Characteristics of Solution-Processed Zinc Tin Oxide Thin-Film Transistors (2012)

We investigated the effects of annealing temperature on the electrical characteristics of solution-processed zinc tin oxide (ZTO) thin-film transistors (TFTs). When the annealing temperature increased from 300 to 500 °C, the threshold voltage of solution-processed ZTO TFTs decreased from 16.89 to -0.23 V owing to the increase in electron concentration in the active layer. The increase in electron concentration is caused by the decrease in Cl atomic concentration. When the annealing temperature increased to 500 °C, the saturation mobility increased from 0.18 to 4.75 cm2·V-1·s-1 and the threshold voltage shift for positive gate bias stress as a reliability characteristic decreased from 5.34 to 2.6 V, because of the decomposition of halide residues such as Cl and the nanocrystallization.