gebhart/patrepeval huggingface dataset:
Electrochemical threshold conditions during electro-optical switching of ionic electrophoretic optical devices (2009)

Electro-optical modulation by electrophoresis of dye ions is a promising technique for applications such as electronic paper displays and nonmechanical beam steering devices. To achieve a sufficient response rate in these devices, the transition time between two different optical states can be decreased by increasing the magnitude of the voltage applied across the electrodes, but this also leads to irreversible and undesirable electrochemical reactions. An electron tunneling model has been developed to describe the electrochemical reaction and to better understand the conditions determining its onset. The model gives rise to three predictions that were subsequently confirmed experimentally: the magnitude of the applied surface charge density should determine the rate of electrochemical activity, the bulk concentration of ions in the solution should shift the threshold voltage at which electrochemical reactions occur, and the reaction rate should be substantially enhanced around nanometer-sized bumps on the electrode surface. Applying this new understanding, the transition time of a device incorporating porous zinc antimonate (ZnSb2O6) electrodes and a solution of Methylene Blue dye in methanol was reduced by a factor of approximately 20.
ChemInform Abstract: Perfluorocarbons as Novel Reaction Media for Photooxidation Reactions. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Examination of Flow Sensitivities in Turbulence Model Validation Experiments (2020)

The use of reduced-scale sensitivity experiments and computational fluid dynamics (CFD) in the design of a large scale three-dimensional bump flow experiment is assessed. The latter aims to provide a benchmark set of data for CFD turbulence model validation. A description is provided of the process by which reduced-scale experiments and CFD are able to effectively and efficiently anticipate design risks of the large scale experiment despite the scarce availability of validation data in the early design stages. The results from two reduced-scale sensitivity experiments and respective CFD simulations of the bump flow exemplify latter assertions. A critical flow separation region on the windward side of the bump geometry, with the potential of obstructing the desired characteristics of the flow, was identified. The analysis shows said region to disappear for target Reynolds numbers and to be laminar in nature, mitigating any risk effectively. Advantages of the methods and means of future improvement are discussed.
NIMG-68. ACCURATE PATIENT-SPECIFIC MACHINE LEARNING MODELS OF GLIOBLASTOMA INVASION USING TRANSFER LEARNING (2017)

Contrast-enhanced MRI (CE-MRI) guides first-line therapies (surgery, radiation) for glioblastoma (GBM), yet its accuracy remains limited. CE-MRI delineates enhancing bulk tumor but poorly characterizes non-enhancing invasive tumor in surrounding T2W abnormality. Previous studies have explored advanced MRI to quantify tumor cell density in non-enhancing T2W abnormality, although absence of validation and conflicting results across studies have hindered clinical translation. In this study, we build and cross-validate a predictive model of tumor cell density, using a novel machine-learning (ML) method called transfer-learning (TL) that integrates multi-parametric MRI and spatially-matched biopsies. While conventional ML generalizes models across an entire patient cohort, TL optimizes predictive accuracies in a patient-specific manner. We collected 82 image-guided biopsies from 18 primary GBM patients throughout T1W-enhancing (T1+C) and nonenhancing T2W regions. For each biopsy, we obtained neuropathologist estimates of tumor cell density (0-100%) and spatially matched texture features on multi-parametric MRI (T1+C, T2W, perfusion, diffusion, tensor). Based on this spatially-matched dataset, we developed a TL model that uses texture features to predict tumor cell density. We optimized TL predictive accuracy using leave-one-out-cross-validation (LOOCV) and measured Pearson correlation (r) and mean absolute errors (MAE) of cross-validated predicted tumor cell density vs. true tumor cell density (within +/- 5% range of neuropathology estimates). We compared accuracies against a conventional ML algorithm LASSO (Least-Absolute-Shrinkage-and-Selection-Operator). TL achieved superior correlation compared to LASSO (r=0.89 vs. r=0.51) across all samples (n=82), as well as within non-enhancing samples (n=32) (r=0.90 vs r=0.37). Compared to LASSO, TL dramatically decreased error rates (MAE), with maximal error reduction observed within non-enhancing samples (MAE 24.7% vs 6.8%). We have developed and cross-validated a TL model that improves the accuracy of prediction of tumor cell density within the non-enhancing T2W zone of GBM.
Commissioning of FLAG: A phased array feed for the GBT (2017)

Abstract Phased Array Feed (PAF) technology is the next major advancement in radio astronomy in terms of combining high sensitivity and large field of view. The Focal L-band Array for the Green Bank Telescope (FLAG) is one of the most sensitive PAFs developed so far. It consists of 19 dual-polarization elements mounted on a prime focus dewar resulting in seven beams on the sky. Its unprecedented system temperature of ~17 K will lead to a 3 fold increase in pulsar survey speeds as compared to contemporary single pixel feeds. Early science observations were conducted in a recently concluded commissioning phase of the FLAG where we clearly demonstrated its science capabilities. We observed a selection of normal and millisecond pulsars and detected giant pulses from PSR B1937+21.
A Device for Human Ultrasonic Echolocation (2015)

Interpreting and interacting with the external world constitutes a major challenge for persons who are blind or visually impaired. This device has the potential to aid blind people in interacting with their environment.
Further work on network interference in wireless ad hoc networks (2009)

It is known that interference is considered as a relationship between link and node in previous works. In this paper, we attempt to capture the physical situation of space-division multiplex more realistically by defining interference as a relationship between any two undirected links. Here a new metric, the average partial interference coefficients, is given. Then we find that the coefficients are almost independent with node density and can be approximated by different linear functions of the length of link respectively. Based on the insight obtained, a new topology control algorithm, the blocked interference minimum algorithm (BIMA), is proposed to control the network interference. Our simulation indicates that the network topologies produced by BIMA show good performance in terms of network interference, energy cost and node degree.
Role of mechanical stress in the resistance drift of Ge2Sb2Te5 films and phase change memories (2011)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation M. Rizzi, A. Spessot, P. Fantini, D. Ielmini; Role of mechanical stress in the resistance drift of Ge2Sb2Te5 films and phase change memories. Appl. Phys. Lett. 28 November 2011; 99 (22): 223513. https://doi.org/10.1063/1.3664631 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioApplied Physics Letters Search Advanced Search |Citation Search
Crystallographic Characterization of 12-Helical Secondary Structure in β-Peptides Containing Side Chain Groups (2010)

Helices are the most extensively studied secondary structures formed by β-peptide foldamers. Among the five known β-peptide helices, the 12-helix is particularly interesting because the internal hydrogen bond orientation and macrodipole are analogous to those of α-peptide helices (α-helix and 3(10)-helix). The β-peptide 12-helix is defined by i, i+3 C═O···H-N backbone hydrogen bonds and promoted by β-residues with a five-membered ring constraint. The 12-helical scaffold has been used to generate β-peptides with specific biological functions, for which diverse side chains must be properly placed along the backbone and, upon folding, properly arranged in space. Only two crystal structures of 12-helical β-peptides have previously been reported, both for homooligomers of trans-2-aminocyclopentanecarboxylic acid (ACPC). Here we report five additional crystal structures of 12-helical β-peptides, all containing residues that bear side chains. Four of the crystallized β-peptides include trans-4,4-dimethyl-2-aminocyclopentanecarboxylic acid (dm-ACPC) residues, and the fifth contains a β(3)-hPhe residue. These five β-peptides adopt fully folded 12-helical conformations in the solid state. The new crystal structures, along with previously reported data, allow a detailed characterization of the 12-helical conformation; average backbone torsion angles of β-residues and helical parameters are derived. These structural parameters are found to be similar to those for i, i+3 C═O···H-N hydrogen-bonded helices formed by other peptide backbones generated from α- and/or β-amino acids. The similarity between the conformational behavior of dm-ACPC and ACPC is consistent with previous NMR-based conclusions that 4,4-disubstituted ACPC derivatives are compatible with 12-helical folding. In addition, our data show how a β(3)-residue is accommodated in the 12-helix, thus enhancing understanding of the diverse conformational behavior of this flexible class of β-amino acids.
Toward simulating entire cities with behavioral models of traffic (2013)

Resilient transportation systems enable quick evacuation, rescue, distribution of relief supplies, and other activities for reducing the impact of natural disasters and for accelerating the recovery from them. The resilience of a transportation system largely relies on the decisions made during a natural disaster. We developed an agent-based traffic simulator for predicting the results of potential actions taken with respect to the transportation system to quickly make appropriate decisions. For realistic simulation, we govern the behavior of individual drivers of vehicles with foundational principles learned from probe-car data. For example, we used the probe-car data to estimate the personality of individual drivers of vehicles in selecting their routes, taking into account various metrics of routes such as travel time, travel distance, and the number of turns. This behavioral model, which was constructed from actual data, constitutes a special feature of our simulator. We built this simulator using the X10 language, which enables massively parallel execution for simulating traffic in a large metropolitan area. We report the use cases of the simulator in three major cities in the context of disaster recovery and resilient transportation.
Cell-Free Expression of Protein Complexes for Structural Biology (2013)

Cell-free protein synthesis is advantageous for the expression of protein complexes, since it is suitable for the co-expression of two or more components of the target protein complexes. The quantity and the quality of cell-free expressed complexes are generally better than those of protein complexes expressed in conventional cell-based systems, because various parameters, such as the stoichiometry of the component proteins, can be more precisely controlled. In this chapter, we describe techniques for the expression of protein complexes by an Escherichia coli cell-free protein synthesis system, which has been successfully utilized in crystallographic structural studies.
Short Term Weight Control Program of Obese Female College Students through Food Consumption Monitoring Using Mobile Phone Equipped with Camera (2010)

This study was conducted to investigate the effects of food consumption monitoring based on a digital photography method using a mobile phone on food consumption and weight reduction. Eighteen female college students (>30% body fat) participated in the weight control program using a mobile-phone for 4 wks. The energy intake was reduced significantly after 3 wks compared to baseline (P of body mass index (BMI) after 4 wks. There were also significant differences in blood pressure (P
Electro‐Assisted Reduction of CO2 to CO and Formaldehyde by (TOA)6[α‐SiW11O39Co(_)] Polyoxometalate (2015)

Abstract We report here on the multiproton‐multielectron electrochemical reduction of CO 2 in homogeneous solution by using (TOA) 6 [α‐SiW 11 O 39 Co(_)] (TOA = tetraoctyl ammonium; _ = vacant position in the coordination sphere of Co) as an electrocatalyst. First, the electrochemical behavior of (TOA) 6 [α‐SiW 11 O 39 Co(_)] was analyzed in detail by cyclic voltammetry in dichloromethane, studying the influence of the presence of protons and/or CO 2 . These preliminary results were further used to optimize the conditions of electrolysis in terms of reduction potentials. Analysis of the electrolysis products in the gas and liquid phases show the formation of CO and HCHO without formation of H 2 . Our results tend to show that the (TOA) 6 [α‐SiW 11 O 39 Co(_)] polyoxometalate is a catalyst for CO 2 electroreduction, with unique selectivity.
Fragile X mental retardation protein is translated near synapses in response to neurotransmitter activation (1997)

Local translation of proteins in distal dendrites is thought to support synaptic structural plasticity. We have previously shown that metabotropic glutamate receptor (mGluR1) stimulation initiates a phosphorylation cascade, triggering rapid association of some mRNAs with translation machinery near synapses, and leading to protein synthesis. To determine the identity of these mRNAs, a cDNA library produced from distal nerve processes was used to screen synaptic polyribosome-associated mRNA. We identified mRNA for the fragile X mental retardation protein (FMRP) in these processes by use of synaptic subcellular fractions, termed synaptoneurosomes. We found that this mRNA associates with translational complexes in synaptoneurosomes within 1-2 min after mGluR1 stimulation of this preparation, and we observed increased expression of FMRP after mGluR1 stimulation. In addition, we found that FMRP is associated with polyribosomal complexes in these fractions. In vivo, we observed FMRP immunoreactivity in spines, dendrites, and somata of the developing rat brain, but not in nuclei or axons. We suggest that rapid production of FMRP near synapses in response to activation may be important for normal maturation of synaptic connections.
Supplementary figures from Transcriptomic Heterogeneity of Androgen Receptor Activity Defines a <i>de novo</i> low AR-Active Subclass in Treatment Naïve Primary Prostate Cancer (2023)

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Molecular Characterization of Drug-Resistant Mycobacterium tuberculosis Isolates Circulating in China by Multilocus PCR and Electrospray Ionization Mass Spectrometry (2011)

We used multilocus PCR and electrospray ionization mass spectrometry (PCR/ESI-MS) to determine the genotype and drug resistance profiles for 96 Mycobacterium tuberculosis isolates circulating in regions of high and low tuberculosis (TB) endemicity in China. The dominant principal genetic group (PGG) circulating in China was PGG1, and drug-resistant gene mutations were more diversified in the region of low rather than high TB endemicity.
Hybrid Polymer Therapeutics Incorporating Bioresponsive, Coiled Coil Peptide Linkers (2010)

This article reports the design, synthesis and results of first in vitro model studies of a conceptually novel class of polymer therapeutics in which the cargo is attached to a polymer backbone via a noncovalent, biologically inspired coiled coil linker, which is formed by heterodimerization of two complementary peptide sequences that are linked to the polymer carrier and the cargo, respectively. In contrast with the polymer-drug conjugates prepared so far, in which the drug is typically attached via an enzymatically or hydrolytically cleavable linker, the noncovalent polymer therapeutics proposed in this article offer several potential advantages, including facile access to combination therapeutics and rapid production of compound libraries to screen for structure-activity relationships. Furthermore, the coiled coil based peptide linkers may not only be useful to bind and release guests but may also play an active role in enhancing and directing intracellular transport and trafficking, which may make these constructs of particular interest for the cytosolic delivery of biomolecular therapeutics.
Forage breeding for changing environments and production systems: an overview (2014)

The 4th International Symposium of Forage Breeding was held at AgriBio, The Centre for AgriBioscience, Melbourne Australia from 23-25 September 2013. More than 100 delegates from around the world attended the symposium which featured sessions on genetic resources and novel species, breeding and managing symbiosis, overcoming abiotic stresses, forage quality and nutritive value, breeding for new environments and production systems, biotic stresses and disease tolerance, economic impact of genetic improvement of forages, new traits and technologies in forage breeding and whole genome selection in forages.
Arsenic-sulfur polydentate ligands. III. Platinum(II) complexes of bis[phenyl(o-thiomethylphenyl)arsino]propane and bis[phenyl(o-thiomethylphenyl)arsino]ethane (1971)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTArsenic-sulfur polydentate ligands. III. Platinum(II) complexes of bis[phenyl(o-thiomethylphenyl)arsino]propane and bis[phenyl(o-thiomethylphenyl)arsino]ethaneDevon W. Meek, R. L. Dutta, and Daryle H. BuschCite this: Inorg. Chem. 1971, 10, 8, 1820–1822Publication Date (Print):August 1, 1971Publication History Published online1 May 2002Published inissue 1 August 1971https://pubs.acs.org/doi/10.1021/ic50102a058https://doi.org/10.1021/ic50102a058research-articleACS PublicationsRequest reuse permissionsArticle Views26Altmetric-Citations6LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
VARIATION IN THE STRUCTURE OF CONDUCTING POLYANILINE WITH AND WITHOUT THE PRESENCE OF TEMPLATE DURING ENZYMATIC POLYMERIZATION: A SOLID-STATE NMR STUDY (2002)

ABSTRACT Polyanilines (PANI) were synthesized from peroxidase-catalyzed polymerization of aniline with and without the presence of a template in the aqueous buffer solution of pH 4.3. The template used was poly(vinylphosphonic acid) (PVP). Solid-state 13C and 15N CP/MAS NMR techniques were applied to characterize the structure of polyaniline in its self-doped conducting, dedoped base, and redoped conducting form of PANI. The charge distribution along the polymer backbone in the protonated form of the polyaniline is also discussed. The structural features exhibited by a template assisted enzymatically synthesized PANI is the result of linear 1,4-coupling of aniline moiety while the PANI synthesized in the absence of template contains both 1,2- and 1,4-coupled products. Solid-state NMR studies on the enzymatically-synthesized polyaniline with the aid of template (PANI-PVP) confirmed the formation of a linear polymer chain containing alternate benzenoid-quinoid repeat units. The dedoped form is in the emeraldine base state of the polyaniline. The structural features in the spectra of the PANI synthesized without a template are quite different. Solid-state NMR data suggest that the PANI synthesized without aid of the template contains structures having C-C and C-N-C coupled products indicating the presence of branching in the polymer chain.
Prompted User Retrieval of Secret Entropy: The Passmaze Protocol. (2005)

A prompting protocol permits users to securely retrieve secrets with greater entropy than passwords. The retrieved user secrets can have enough entropy to be used to derive cryptographic keys.
Elastic immersive wave experimentation: Theory and physical implementation (2019)

A physical elastic experimentation domain is immersed within a numerically modeled environment by actively cancelling the boundary reflections at the free surface of a solid target and replacing them with interactions from a desired exterior environment. The paper presents a theoretical derivation for elastic immersive experimentation, as well as the first experimental demonstration in a beam using a state-of-the-art laser doppler vibrometer and three-component piezo electric actuators.
Sensors from electrodeposited metal nanowires (2002)

Abstract Based on their electronic conductivity behaviour, metallic nanowires may have analytical applications ranging from interconnects to sensors. We present in this paper an electrochemical method for synthesizing Mo and Pd metal nanowires ranging in diameter from a few tens of nanometres up to one micrometre, with millimetre lengths. Nanowires are prepared by the electrodeposition of metal at step edges present on a graphite surface. These nanowires can be used to connect metal nanoparticles (Ni, Au, etc.). Once transferred in a polymer cast, they can operate as sensors. We describe how these nanowires may be manipulated to make devices for analytical chemistry and, as an example of such nanodevice, a detailed overview of the characteristics of the first nanowire‐based sensor of hydrogen gas (H 2 ) is given. Copyright © 2002 John Wiley &amp; Sons, Ltd.