gebhart/patrepeval huggingface dataset:
A High-Speed CMOS Image Sensor with On-chip Parallel Image Compression Circuits (2007)

This paper presents a high-speed CMOS image sensor with on-chip parallel image compression circuits. The chip consists of a pixel array, an A/D converter array with noise canceling function and an image compression processing element array and buffer memories. The image compression processing element is implemented with a 4×4 point Discreate Cosine Transform(DCT) and a modified zigzag scanner with 4 blocks. A prototype high-speed CMOS image sensor integrating the image compression circuits is implemented based on 1-poly 5-metal 0.25- <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">μ</i> m CMOS technology. Image encoding using the implemented parallel image compression circuits to the image captured by the high-speed image sensor is successfully performed at 3,000[frame/s].
Medication utilization among vascular dementia population (2021)

Abstract Background It is estimated that up to 40% of Alzheimer’s Disease and Related Dementias cases can be prevented or delayed by addressing modifiable factors including those that influence vascular risk (hypertension, obesity, smoking, physical activity, diabetes). Prevention may be particularly important in the vascular dementia subtypes. Despite the supporting evidence, the rates of medical therapy to reduce vascular risk are not well described. Method We assessed the utilization of statins, aspirin, and blood pressure (BP) medications in adults age ≥65 years cared for at NYU Langone Health, as recorded in the electronic health record. We included two cohorts: cohort 1 included patients who were diagnosed with vascular dementia (VaD) at NYU Langone Barlow Center for Memory Evaluation between January 1, 2015 and June 24, 2019. Cohort 2 extended the inclusion to seniors with VD diagnosis by any NYU Langone physician. Definitions for vascular dementia, the covariates assessed, and medications that we included in each category are shown in Tables 1‐3. Result We included 419 and 3745 patients in cohort 1 and cohort 2, respectively. Table 4 shows the characteristics and medication adherence in cohorts 1 and 2. In cohort 1, the prescription rates for statins, aspirin, and BP medications were 66%, 66%, 70%. In cohort 2, the rates for statin, aspirin, and BP medications were 56%, 46%, and 65%, respectively. The differences between prescription rates in cohort 1 and 2 for the three medication groups were statistically significant (p&lt;0.05). Conclusion Our analysis of the utilization of cardiovascular medications among patients with vascular dementia illuminates potential gaps both among patients who receive care at specialty clinics, as well as the overall population with vascular dementia. The rates of medication utilization are higher for patients under the care of cognitive neurologists. Electronic health records can help identify large cohorts of patients who may benefit from improved access to preventative measures including cardiovascular medications.
Multi-Band All-Digital Transmission for 5G NG-RAN Communication (2020)

This paper explores multi-band all-digital transmitter architecture suitable for 5G next-generation radio access network (NG-RAN). In NG-RAN, most of the radio frequency (RF) layer functions are moved to a distributed unit (DU) in the digital domain so that a low cost and small size remote radio unit (RRU) can be developed. This paper presents a delta-sigma modulation (DSM) technique implemented in the field-programmable gate array (FPGA) for DU which is further interfaced with a power amplifier in RRU through feeder cable. A single bit 1st and $2^{\mathrm{n}\mathrm{d}}$ order low-pass DSM is implemented in FPGA of DU. An IQ sequencing block and high-speed serializer multiplexer are used to digitally up-convert the baseband signals to the different carrier frequencies in DU. The proposed scheme is validated with transmission of long-term evolution (LTE) signal of 5 MHz bandwidth for single as well as multi-band operation. The performance of the transmitter is measured in terms of signal to noise distortion ratio (SNDR) and error vector magnitude (EVM).
Material Study for Electrowetting-Based Multi-Microfluidics Array Printing of High Resolution Tissue Construct With Embedded Cells and Growth Factors (2010)

Tissue engineering (TE) is evolving as a potential solution for repair and reconstruction of diseased or damaged tissues. TE faces major manufacturing challenges: manufacturing techniques are needed to mimic tissue and extra cellular matrix (ECM) architecture, with high resolution (less than 10 μm) for tissues such as myocardium (heart muscle), blood vessels, bone or nerves; innovative methods are needed for delivery of cells and growth factors into scaffolds; and manufacturing techniques are needed to create vascular structure in tissue construct; lack of nutrient transport currently limits the size and cellular content of implants.
Successful Treatment of Allopurinol-Induced Severe Skin Reactions with Double Filtration Plasmapheresis: A Case Report (2020)

Severe cutaneous adverse reactions (SCAR) are uncommon and acute and frequently represent a drug reaction. For years, allopurinol use has remained the highest risk factor for SCARs worldwide. There are multiple risk factors for allopurinol-induced SCARs, including genetic and non-genetic factors. Renal failure has been found to be an important factor resulting in allopurinol-induced SCARs with greater severity and poorer prognosis. An 80-year-old female was admitted to our hospital after administration of allopurinol in December 2018. She developed erythaematous skin of the epidermis of the hips, which rapidly extended over the trunk and limbs, resulting in itching and flaking. The presumptive diagnosis was a drug-induced SCAR. Despite treatment with glucocorticoids and kidney support therapy, the skin lesions extended over the entire body. Fortunately, the progression of pruritic erythema was stopped by double-filtration plasmapheresis (DFPP). DFPP was discontinued after the signs of skin inflammation were no longer visible. Her skin, but not kidney function, recovered after 10 days of hospitalization. She tolerated DFPP well without development of any severe complications. We present here a case of allopurinol-induced SCAR, which was successfully treated with DFPP.
On the synthesis and destruction of A- and B-type cyclins during oogenesis and meiotic maturation in Xenopus laevis. (1991)

We have measured the levels of cyclin mRNAs and polypeptides during oogenesis, progesterone-induced oocyte maturation, and immediately after egg activation in the frog, Xenopus laevis. The mRNA for each cyclin is present at a constant level of approximately 5 x 10(7) molecules per oocyte from the earliest stages of oogenesis until after fertilization. The levels of polypeptides show more complex patterns of accumulation. The B-type cyclins are first detectable in stage IV and V oocytes. Cyclin B2 polypeptide is present at approximately 2 x 10(9) molecules (150 pg) per oocyte by stage VI. The amount increases after progesterone treatment, but returns to its previous level after GVBD and undergoes no further change until it is destroyed at fertilization. Cyclin B1 is present at 4 x 10(8) molecules per oocyte in stage VI oocytes, and rises steadily during maturation, ultimately reaching similar levels to cyclin B2 in unfertilized eggs. Unlike the B-type cyclins, cyclin A is barely detectable in stage VI oocytes, and only starts to be made in significant amounts after oocytes are exposed to progesterone. A portion of all the cyclins are destroyed after germinal vesicle breakdown (GVBD), and cyclins B1 and B2 also experience posttranslational modifications during oocyte maturation. Progesterone strongly stimulates both cyclin and p34cdc2 synthesis in these oocytes, but whereas cyclin synthesis continues in eggs and after fertilization, synthesis of p34cdc2 declines strongly after GVBD. The significance of these results is discussed in terms of the activation and inactivation of maturation-promoting factor.
JacquardToolkit (2019)

New user interfaces afford innovations in the user experience of computers- the interactive textile approach posed by Jacquard is another step in this evolution[1, 5]. Although it demonstrates four gestures via the Levi's Jacquard Jacket [4], we experiment with potential applications to explore new forms of user inputs. We have built a toolkit that enables developers full access to the Jacquard technology and custom gesture creation [2, 3]. We subsequently used this to develop a custom Force Touch gesture, which is now integrated into the aforementioned iOS toolkit such that developers may use it to implement original and new jacket functionality into their own applications. The playground application helps developers understand how to effectively utilize the library. In parallel, we evaluated the Jacquard hardware by conducting a detailed tear down of the Jacket cuff and tag. We mapped how such sensing technology can be removed from the jacket and applied to other textiles with conductive threads. Moreover, our findings motivate future testing on other garments and accessories as we isolated the Jacquard swatch from the cuff. In order to evaluate the intuitiveness of the jacket gestures and test learnability of the new custom gestures, we designed a user assessment application with the toolkit to conduct a user study with 25 subjects. Results showed that both Brush In and Brush Out had the easiest learning curve and were perceived as most intuitive. Brush In (48%) stood out as the most preferred gesture followed by Double Tap (20%). Although the custom gesture, Force Touch, had the lowest perceived intuitiveness, it serves as the first key step towards a future of rapidly prototyped and consumer-ready custom gestures.
Hydrogen Permeation Behavior Changed with Size of Scratch Formed on Zinc Coated Steels During Wet-Dry Cycle Corrosion (2017)

乾湿繰り返し腐食試験を用いて，きず（0 mm2, 0.3 mm2 and 1.5 mm2）を形成したZnめっき鋼板からの水素透過挙動を調査した．きずの面積に関係なく，腐食試験中に同じような形状を有する水素透過電流が測定された．試験終了後，試験片表面には白色の腐食生成物が生成した．水素透過電気量は3サイクルまで増加し，その後減少した．きず周辺の腐食生成物は，塩基性塩化亜鉛であった．このことから，長期間の腐食試験で水素透過電気量が減少するのは，この腐食生成物の形成によることが示唆された．3サイクルまでの水素透過電気量ときず面積の比較から，発生した水素はきず部から均一に鋼中に侵入しないことが示唆された．
Influence of Epi-Layer Growth Pits on SiC Device Characteristics (2015)

Homoepitaxial layers with different growth pit density were grown on 4 H -SiC Si-face substrates by changing C/Si ratio, and the influence of the growth pit density on Schottky barrier diodes and metal-oxide-semiconductor capacitors were investigated. Even though there were many growth pits on the epi-layer, growth pit density did not affect the leakage current of Schottky barrier diodes and lifetime of constant current time dependent dielectric breakdown. By analyzing the growth pit shape, the aspect ratio of the growth pit was considered to be the key factor to the leakage current of the Schottky barrier diodes and the lifetime of metal-oxide-semiconductor capacitors.
Proteome and metabolome profiling of cytokinin action in Arabidopsis identifying both distinct and similar responses to cytokinin down- and up-regulation (2013)

In plants, numerous developmental processes are controlled by cytokinin (CK) levels and their ratios to levels of other hormones. While molecular mechanisms underlying the regulatory roles of CKs have been intensely researched, proteomic and metabolomic responses to CK deficiency are unknown. Transgenic Arabidopsis seedlings carrying inducible barley cytokinin oxidase/dehydrogenase (CaMV35S>GR>HvCKX2) and agrobacterial isopentenyl transferase (CaMV35S>GR>ipt) constructs were profiled to elucidate proteome- and metabolome-wide responses to down- and up-regulation of CK levels, respectively. Proteome profiling identified >1100 proteins, 155 of which responded to HvCKX2 and/or ipt activation, mostly involved in growth, development, and/or hormone and light signalling. The metabolome profiling covered 79 metabolites, 33 of which responded to HvCKX2 and/or ipt activation, mostly amino acids, carbohydrates, and organic acids. Comparison of the data sets obtained from activated CaMV35S>GR>HvCKX2 and CaMV35S>GR>ipt plants revealed unexpectedly extensive overlaps. Integration of the proteomic and metabolomic data sets revealed: (i) novel components of molecular circuits involved in CK action (e.g. ribosomal proteins); (ii) previously unrecognized links to redox regulation and stress hormone signalling networks; and (iii) CK content markers. The striking overlaps in profiles observed in CK-deficient and CK-overproducing seedlings might explain surprising previously reported similarities between plants with down- and up-regulated CK levels.
A novel cis element essential for stimulated transcription of the p41 promoter of human herpesvirus 6 (1994)

The p41 DNA-binding protein of human herpesvirus 6 is an apparent processivity factor important for viral DNA replication. The p41 promoter was characterized to understand how this processivity factor is regulated. A single transcription start site and a functional TATA box are located 48 and 74 bp, respectively, upstream of the start codon. A reporter construct containing 1,027 bp of the sequence upstream of the p41 start codon was inactive in uninfected T cells but functioned as a strong promoter in human herpesvirus 6-infected cells. Mutational analysis identified a 21-bp element (the EA site) which is located at -73 to -52 bp relative to the transcription start site and is essential for promoter activity. The ability of the EA site to stimulate transcription optimally appears to be strictly dependent upon its distance from the p41 basal promoter. The EA site contains three overlapping sequences, a CAAT-enhancer-binding protein (C/EBP) transcription factor recognition site and two repeat elements. Mobility shift assays using the EA site identified four binding activities (C1 to C4). C1 and C2 are present in both uninfected and infected cells and do not contain C/EBP factors. In infected cells, point mutation of the EA site abrogates C1 and C2 binding activities and destroys transcriptional activity of the p41 promoter. C3 and C4 are present in uninfected cells only and were found to contain C/EBP factors. These findings indicate that in infected cells, transcriptional stimulation of the p41 promoter by the EA site requires C1 and C2 binding activities. These results further suggest that transcriptional activity may also depend upon the elimination of C3 and C4 binding activities.
Influence of Absorption by Environmental Water Vapor on Radiation Transfer in WildLand Fires (2008)

The attenuation of radiation transfer from wildland flames to fuel by environmental water vapor is investigated. Emission is tracked from points on an idealized flame to locations along the fuel bed while accounting for absorption by environmental water vapor in the intervening medium. The Spectral Line Weighted-sum-of-gray-gases approach was employed for treating the spectral nature of the radiation. The flame and fuel bed for the simulations are modeled two-dimensionally with the flame being one-tenth as long as the fuel bed. Flame heights of 1 and 10 m were explored, and both vertical and angled flames were studied. Simulated flame temperatures of 1000 K and 1500 K were investigated. The study reveals that the effect of absorption of flame radiation by environmental water vapor is quite modest locally. For the worst-case scenario of 100% relative humidity, water vapor was found to reduce the incident radiant flux at the base of a vertically oriented flame at 1000 K flame by 9% for a 1 m flame and 16% for a 10 m flame. Radiation from the angled flame (30 deg from the vertical) experiences less attenuation from water vapor than the vertical flame. Further, local attenuation of the hotter flame (1500 K) from environmental water vapor is higher than for the 1000 K flame. The relative effect of the water vapor attenuation increases with distance from the flame base.
Involvement of both intrinsic and extrinsic cell death pathways by 8-amino-adenosine in multiple myeloma (2005)

3264 Multiple Myeloma (MM) is an indolent B-cell malignancy, which readily becomes resistant to traditional chemotherapeutic agents. The novel adenosine analog, 8-amino-adenosine (8-NH2-Ado), has been evaluated as a potential therapeutic molecule (Mol Cancer Ther 3:1411, 2004). Studies of 8-NH2-Ado in the MM cell line, MM.1S demonstrated cytotoxicity with an IC50 of 300 nM to 3 μM. The analog accumulated as its triphosphate, 8-NH2-ATP, with a simultaneous decrease in the intracellular ATP pool. Additionally, incubation with 8-NH2-Ado predominantly inhibited RNA synthesis, which is a unique characteristic because analogs such as cladribine and fludarabine primarily inhibit DNA synthesis. The DNA-directed nucleoside analogs initiate cell death primarily through the intrinsic pathway of cell death. Because the mechanism of action of 8-NH2-Ado is RNA directed with an effect on cellular bioenergy, it is likely that cell death may be induced through multiple pathways. To test this postulate, caspase activation was quantified by fluorometric assays. Upon treatment of MM.1S cells with 10 μM 8-NH2-Ado for 12 hrs, caspases-8 and -10 were activated 26- and 46-fold, respectively, suggesting that the extrinsic cell death pathway is involved. In addition, caspases that participate in the intrinsic cell death pathway such as caspases-9, -6, and -3 were activated 28-, 22-, and 9-fold under these conditions. In contrast to these caspases, the endoplasmic reticulum stress related caspase-12 was not activated. To determine the temporal relationship between extrinsic and intrinsic cell death pathways and to identify the initiating caspases, activation of caspases-8 and -9 was evaluated at early time points. Both caspases-8 and -9 were activated at 2 hrs indicating involvement of both these routes for 8-NH2-Ado induced cell death. Previous studies have demonstrated that proapoptotic proteins Bax and Bak induce cell death through the mitochondrial (intrinsic cell death) pathway. To investigate if 8-NH2-Ado could induce cell death in cells lacking Bax and Bak, apoptosis of wild-type and Bax/Bak double knock-out (DKO) MEFs was analyzed by Annexin V binding after incubations with 8-NH2-Ado. Following 6 hrs of treatment with 5 μM 8-NH2-Ado, 65% of the wild type MEFs were Annexin positive, whereas only 31% of the DKO cells were positive, but this value increased to 67% by 18 hrs in DKO cells. Hence, while 8-NH2-Ado was able to induce apoptosis in the DKO cells, the effect was delayed by 12 hrs compared to the WT cells suggesting that both the intrinsic and extrinsic pathways are required for efficient 8-NH2-Ado induced cytotoxicity. Ongoing investigations focus on the upstream signaling of these pathways by 8-NH2-Ado in order to understand the mechanism of cell death by this RNA-directed nucleoside analog.
Equivalent circuit model of a Ge/Si avalanche photodiode (2009)

An equivalent circuit model for a separate-absorption-charge-multiplication Ge/Si avalanche photodiode is presented. The current dependence of the resonance frequency scales with square root of current, as expected.
ChemInform Abstract: A Short Total Synthesis of Estrone Derivatives: A Novel 1,3‐ Rearrangement of an Allylic Nitro Group. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Supplementary Table 3 from Evaluation and Clinical Analyses of Downstream Targets of the Akt Inhibitor GDC-0068 (2023)

&lt;p&gt;PDF file 168K, Pearson and Spearman correlation with survival fraction for all cell lines together or individual cell lines&lt;/p&gt;
Session 21 overview: Innovative personalized biomédical systems: Technology directions subcommittee (2015)

Advanced biomedicai systems-on-chip combined with miniaturized sensors and actuators offer new perspectives in the field of low-cost, portable, connected or self-monitored healthcare applications. Such technologies enable early diagnosis and personal therapy outside of a traditional clinical environment, increasing the autonomy and level of comfort of the patient.
Socio-Cyberphysical System for Parking Support (2016)

The paper proposes an approach and its supporting technologies for building a socio-cyberphysical system aimed at intelligent driver support. The approach is based on usage of such technologies as smart space for communication possibilities, behavior analysis for personalized support and human decision foreseeing, and fuzzy constraint satisfaction for treating uncertainties arising in stochastic systems such as traffic. The application of the approach is illustrated via a parking spot searching case study.
Competing Exchange Interactions in Magnetic Multilayers (2006)

We have studied alloying of the nonmagnetic spacer layer with a magnetic material as a method of tuning the interlayer coupling in magnetic multilayers. We have specifically studied the Fe/V(100) system by alloying the spacer V with various amounts of Fe. For some Fe concentrations in the spacer, it is possible to create a competition between antiferromagnetic Ruderman-Kittel-Kasuya-Yoshida exchange and direct ferromagnetic exchange coupling. The exchange coupling and transport properties for a large span of systems with different spacer concentrations and thicknesses were calculated and measured experimentally and good agreement between observations and theory was observed. A reduction in magnetoresistance of about 50% was observed close to the switchover from antiferromagnetic to ferromagnetic coupling.
Bi 2 Ti 2 O 7 ‐based pyrochlore nanoparticles and their superior photocatalytic activity under visible light (2017)

Abstract Nanoparticles of Bi 2 Ti 2 O 7 pyrochlore were synthesized by a coprecipitation method. They exhibit a high visible‐light photoactivity for decolorization of a methyl‐orange dye solution in the presence of a sacrificial agent, H 2 O 2 . The same pyrochlore system with an Ag co‐catalyst showed even faster kinetics under only visible light and an unprecedentedly high photoactivity in the UV range.
Hemodynamics by interferometric photonics (2014)

Between January 1 and March 15, 1974, approximately 1200 cases of acute gastrointestinal illness occurred in Richmond Heights, Florida, a residential community of 6500 in south Dade County. Over one-third of all families in the area had at least one member affected. The findings of 10 culture-proven cases of shigellosis among those who became ill and clinical signs and symptoms in the others suggest that most of the other cases that were not cultured may have been shigellosis also. Epidemiologic investigation showed that consumption of tap water was associated with illness in the initial cases of affected families. Evaluation of the Richmond Heights public water supply disclosed numerous inadequacies in both design and operation. One of the wells providing water to the community was continuously contaminated with excessive levels of fecal coliforms from a nearby septic tank, and a breakdown in chlorination on January 14-15 caused approximately 1 million gallons of inadequately chlorinated water from the contaminated well to be distributed to the community 48 hours before the epidemic began. Correction of deficiencies in the water plant was undertaken by the utility company; the residents of Richmond Heights were instructed to boil their drinking water or to use commercially bottled water pending completion of corrective measures. A FUll scale study is planned for all similar public water supplies in Dade County.