gebhart/patrepeval huggingface dataset:
Transparent organic light-emitting devices using a MoO3/Ag/MoO3 cathode (2011)

MoO3/Ag/MoO3 (MAM) stacks are investigated for utilization as transparent cathodes in organic light-emitting devices (OLEDs). The stacks can be fabricated using simple thermal evaporation at relatively low temperatures, and can be readily and safely utilized as top electrodes, without causing deposition damage to the organic layers. Results show that it is possible to achieve efficient electron injection from the MAM electrode into organic layers by means of incorporating a suitable electron injection layer (EIL) at the interface. Results also show that a MAM stack can exhibit high optical transmittance, amounting to about 65–80% in the 400–700 nm, and a low sheet resistance (9 Ω/□). A transparent OLED with a MAM cathode incorporated with a 10 nm Bphen: Cs2CO3 (10%) EIL is studied. By fine tuning the MAM structure, optimal OLED performance has been achieved: a total luminance of 1300 cd/m2 (representing ∼1000 cd/m2 and ∼300 cd/m2 from the bottom and the top, respectively) at 20 mA/cm2 and a corresponding driving voltage of 7.2 V. The OLED exhibits a peak transmittance of ∼90% in the 450–475 nm range, and a transmittance above 45% over the entire visible (i.e., 400–700 nm) range.
The Efficacy of Co-Treatment with Suberoylanilide Hydroxamic Acid and Mitomycin C on Corneal Scarring after Therapeutic Keratectomy: An Animal Study (2014)

Treatment with SAHA in combination with a low dose of MMC could be a novel and effective therapeutic strategy to suppress the proliferation of corneal myofibroblasts, thereby inhibiting corneal fibrosis or haze with minimal ocular surface toxicity.
The propagation of single-cycle THz pulses in random media (2003)

Summary from only given. We report the first measurements of the transmission of single-cycle THz pulses through a random medium. A model random medium can be constructed using commercially available polytetrafluoroethylene (PTFE, teflon) spheres (n = 1.43). The spheres are contained in a teflon sample cell, with windows a fixed distance apart. In order to perform length-dependent studies, we fabricated fifty such cells.
Genetic engineering of a hypoallergenic trimer of the major birch pollen allergen, Bet v 1 (2001)

An estimated 100 million individuals suffer from birch pollen allergy. Specific immunotherapy, the only curative allergy treatment, can cause life-threatening anaphylactic side effects. Here, we report the genetic engineering of a recombinant trimer consisting of three covalently linked copies of the major birch pollen allergen, Bet v 1. The trimer exhibited profoundly reduced allergenic activity but contained similar secondary structures such as Bet v 1 wild type, Bet v 1-specific B cell and T-cell epitopes, and induced Th1 cytokine release. As immunogen, rBet v 1 trimer induced IgG antibodies, which blocked patients' IgE binding to Bet v 1 and related allergens. Thus, rBet v 1 trimer represents a novel hypoallergenic vaccine prototype for treatment of one of the most frequent allergy forms.
Surface-assisted Photomanipulation of Orientation of a Polymer Liquid Crystal (1999)

Abstract The alignment photocontrol of liquid crystalline polymer films was achieved by a thin film of a polymethacrylate with p-cyanoazobenzene side chains as a command layer, which was exposed to linearly polarized light in advance.
Computational Analysis of an Evolutionarily Conserved Vertebrate Muscle Alternative \nSplicing Program (2006)

A novel exon microarray format that probes gene expression with single exon resolution was employed to elucidate critical features of a vertebrate muscle alternative splicing program.A dataset of 56 microarray-defined, muscle-enriched exons and their flanking introns were examined computationally in order to investigate coordination of the muscle splicing program.Candidate intron regulatory motifs were required to meet several stringent criteria: significant over-representation near muscle-enriched exons, correlation with muscle expression, and phylogenetic conservation among genomes of several vertebrate orders.Three classes of regulatory motifs were identified in the proximal downstream intron, within 200nt of the target exons: UGCAUG, a specific binding site for Fox-1 related splicing factors; ACUAAC, a novel branchpoint-like element; and UG-/ UGC-rich elements characteristic of binding sites for CELF splicing factors.UGCAUG was remarkably enriched, being present in nearly one-half of all cases.These studies suggest that Fox and CELF splicing factors play a major role in enforcing the muscle-specific alternative splicing program, facilitating expression of a set of unique isoforms of cytoskeletal proteins that are critical to muscle cell differentiation.Supplementary materials: There are four supplementary tables and one supplementary figure.The tables provide additional detailed information concerning the muscle-enriched datasets, and about overrepresented oligonucleotide sequences in the flanking introns.The supplementary figure shows RT-PCR data confirming the muscle-enriched expression of exons predicted from the microarray analysis.
Structural analysis of polymeric scaffolds by Micro-CT (2006)

The use of porous structures as tissue engineering scaffolds imposes demands on structural parameters such as porosity, pore size and interconnectivity. For the structural analysis of porous scaffolds, micro-computed tomography (μCT) is an ideal tool. μCT is a 3D X-ray imaging method that has several advantages over scanning electron microscopy (SEM) and other conventional characterisation techniques: • visualisation in 3D • quantitative results • non-destructiveness • minimal sample preparation
Efficient emission of positronium negative ions from Cs deposited W(100) surfaces (2008)

The emission of positronium negative ions from Cs deposited W(100) surfaces has been studied. A dramatic change in the emission efficiency was observed upon coating a W(100) surface with Cs. The conversion efficiency (the fraction of incident slow positrons yielding the ions) of the W(100) target with a 2.2×1014 atoms cm- 2 Cs coverage, measured over a time interval of 3×103 s immediately after deposition, was found to be 1.25%, which is two orders of magnitude higher than that obtained for the clean, uncoated W(100) surface and 45 times greater than the highest efficiency reported thus far.
A Study on Safer Operation of Impulsively Loaded Vessels (2009)

ASME published Code Case 2564 [1] in January 2008 on impulsively loaded vessels, which is the first design guidance of this kind worldwide. The authors participated in the Task Group of Sec. VIII, Div. 3 [2] and were also intimately engaged in development, design and operation of detonation chambers DAVINCH®. DAVINCH® is an acronym for Detonation of Ammunition in Vacuum INtegrated CHamber, utilized for destruction of old non-stockpile chemical weapons, which were recovered from underground and sea in several areas of Japan, China, and Belgium. The quantity destroyed to-date has reached as high as 4,500 items. Figure 1, and 2 show the installations of DV65 at Port Kanda, Japan and DV50 at Poelkapelle, Belgium, with maximum capacity of 65kg and 50 kg TNT-equivalent respectively.
Collagen VI deficiency causes behavioral abnormalities and cortical dopaminergic dysfunction (2022)

Mutations of genes coding for collagen VI (COL6) cause muscle diseases, including Ullrich congenital muscular dystrophy and Bethlem myopathy. Although COL6 genetic variants were recently linked to brain pathologies, the impact of COL6 deficiency in brain function is still largely unknown. Here, a thorough behavioral characterization of COL6-null (Col6a1-/-) mice unexpectedly revealed that COL6 deficiency leads to a significant impairment in sensorimotor gating and memory/attention functions. In keeping with these behavioral abnormalities, Col6a1-/- mice displayed alterations in dopaminergic signaling, primarily in the prefrontal cortex. In vitro co-culture of SH-SY5Y neural cells with primary meningeal fibroblasts from wild-type and Col6a1-/- mice confirmed a direct link between COL6 ablation and defective dopaminergic activity, through a mechanism involving the inability of meningeal cells to sustain dopaminergic differentiation. Finally, patients affected by COL6-related myopathies were evaluated with an ad hoc neuropsychological protocol, revealing distinctive defects in attentional control abilities. Altogether, these findings point towards a previously undescribed role for COL6 in the proper maintenance of dopamine circuitry function and its related neurobehavioral features in both mice and humans. This article has an associated First Person interview with the first author of the paper.
Modelling Wireless Propagation for Indoor Localization (2016)

This paper presents a ray-tracing technique to model the multi-path fading effect in indoor spaces. Random set P of points on all surfaces inside a given hypothetical indoor space are chosen. Each p i P is considered to be a point from which the transmitted signal reflects just before reaching the receiver. The received signal is the vector sum of various reflections that arrive at the receiver. The received signal strength (RSS) is then computed from the signal envelope. This technique provides RSS statistics that are similar to the models of signal propagation developed after extensive measurements in multi-path environments. In addition, this technique captures the spatial correlation of signal impairment. For example, path loss computed with this technique shows that co-moving receivers experience correlated signal fades while those moving in different spaces see un-correlated fading. The technique presented here is a low cost, first principle approach to simulate channel impairments due to multi-path effect and interference. It benefits any wireless simulation study that needs the signal-space mapping and context such as indoor localization. This randomized ray-tracing technique does not compete with or replace other, more accurate ray-tracing techniques that use either brute force or geometric optics to obtain site-specific signal-to-space mapping.
Bandgap Engineering of Conjugated Nanoporous Poly‐benzobisthiadiazoles via Copolymerization for Enhanced Photocatalytic 1,2,3,4‐Tetrahydroquinoline Synthesis under Visible Light (2016)

Abstract Conveniently combining properties such as high interfacial surface area, excellent visible light absorption and semiconductor‐range bandgap, conjugated nanoporous polymer networks are promising candidates as pure organic, metal‐free, visible light‐responsive and heterogeneous photocatalysts. Here, a facile yet precise bandgap engineering strategy to achieve fine justification of the valence and conduction band positions of a series of nanoporous polymers to optimally bracket the redox potential of the targeted individual photoredox reaction via copolymerization of the electron‐withdrawing benzobisthiadiazole moieties into the polymer network backbone is presented. The enhanced photocatalytic activity of the nanoporous polymer networks was demonstrated in the synthesis of 1,2,3,4‐tetrahydroquinoline, an important motif in pharmaceutical compounds, via photooxidative cyclization of N , N ‐dimethylanilines with maleimides. magnified image
Patterning of thick electroplated CoPt magnets using SU‐8 micromoulds (2019)

Recently, electroplated cobalt platinum (CoPt) magnetic films have been developed that afford thick (up to ∼100 μm), high‐energy‐density (up to ∼100 kJ/m 3 ) permanent‐magnet microstructures. However, the aggressive electroplating conditions have shown to be incompatible with most thick‐film photoresist mould materials, making patterning these films an unanswered technical challenge. In this work, it is reported a complete process flow of fabricating and removing SU‐8 photoresist moulds to enable the ultra‐thick patterned CoPt magnets on silicon wafers. The implementation of thick SU‐8 2050 electroplating moulds makes it feasible to deposit 100 µm thick CoPt magnets in 4 h. A 25 nm thick sputtered titanium layer is used as a sacrificial layer to completely release the SU‐8 mould in hydrofluoric acid after electrodeposition. Compared to prior research, significantly improved pattern definition and constant magnetic performance are observed and characterised by optical profilometer, scanning electron microscope, and vibrating sample magnetometer.
Principle and applications of a new MOEMS spectrometer (2006)

Near Infrared (NIR) spectroscopy has developed to an important and useful analysis method over the past years. The existence of compact, portable devices offers a lot of applications possibilities, even in harsh environments. Compact devices, mostly based on detector arrays, are quite costly caused by the expensive Indium Gallium Arsenide (InGaAs) detector arrays. By using MOEMS the set-up can be realised much more efficiently. With an adapted optical set-up detector arrays can be replaced by single element detectors. We have realised a new miniaturised spectrometer based on a scanning micro mirror. The mirror is combined with a diffraction grating and other optical components. It periodically disperses the polychromatic radiation into its spectral components. The radiation is measured by an InGaAs-single element detector, which can be thermoelectrically cooled depending on the application. The radiation coupling is possible either directly or by using fiber optics. It allows an easy attachment of substance samples for reflectance measurements as well as attenuated total reflection (ATR) probes, cuvette holders and flow cells. Lowest noise preamplifiers enable high-precise measurements over a wide dynamic range. With a spectral range of 1000 - 2100 nm and a spectral resolution of approx. 12 nm the device is able to fulfill various requirements. Applications for food stuff industry; clinical chemistry and identification of polymers were tested and will be discussed. Furthermore we will show the advanced optical and mechanical design. In addition advanced performance issues and reliability test results of the device will be reviewed.
Probing Organic Field Effect Transistors In Situ during Operation Using SFG (2006)

In this communication, we report results obtained using surface-sensitive IR+Visible Sum Frequency Generation (SFG) nonlinear optical spectroscopy on interfaces of organic field effect transistors during operation. We observe remarkable correlations between trends in the surface vibrational spectra and electrical properties of the transistor, with changes in gate voltage (VG). These results suggest that field effects on electronic conduction in thin film organic semiconductor devices are correlated to interfacial nonlinear optical characteristics and point to the possibility of using SFG spectroscopy to monitor electronic properties of OFETs.
Do Cemented Dual-Mobility Cups Confer Stability for Patients at High Risk of Dislocation in Revision Total Hip Arthroplasty? (2018)

Abstract Dislocation is among the most commonly reported complications following revision total hip arthroplasty. Dual-mobility bearings may lower the risk of dislocation. The authors report the results of a multicenter study evaluating the use of a dual-mobility acetabular cup design that was cemented into a metal shell as part of complex acetabular reconstructions or in cases where the risk of dislocation was felt to be high, such as isolated bearing exchanges. Eighteen patients were identified for being at high risk of dislocation who underwent cementation of a dual-mobility shell that is specifically made for cementation, into a fully porous metal revision acetabular cup (10 patients) or into a well-fixed cup at the time of revision without removal of the existing acetabular component (eight patients). Patients were assessed clinically and radiographically at a minimum of 2 years for the evidence of dislocation, revision surgery, and implant loosening. At a mean of 36 months (range, 25–56 months), one patient died and one was lost to follow-up. There were no known cases of hip dislocation. There was one repeat revision, for a deep infection treated with irrigation and debridement. The mean preoperative Harris Hip Score of 46 (range, 40–79) improved to a mean of 65 points (range, 41–97) at the most recent evaluation. Acetabular components were retained in 8 out of 18 cases and the dual-mobility shell was cemented into it. Cementation of a dual-mobility cup into a shell at the time of a revision surgery is a safe and reliable construct at minimum of 2 years for patients at high risk of dislocation. There were no complications related to the cementation of the cup into the metal shell. Longer follow-up is required to further assess the durability of this construct.
OCDMA light source using directly modulated Fabry-Pe/spl acute/rot laser diode in an external injection scheme (2006)

This investigation proposes and experimentally demonstrates an optical code-division multiple-access (OCDMA) light source using a directly modulated Fabry-Pe/spl acute/rot laser diode in an external injection scheme. This light source has an optical sidemode suppression ratio of over 27.5 dB and a pulsewidth of around 55 ps. Such a narrow pulsewidth has great potential for a two-dimensional OCDMA system. Additionally, the bit-error-rate performance with a 2/sup 31/-1 pseudorandom bit sequence indicates the feasibility of this light source in a 2.488-Gb/s system application.
ChemInform Abstract: Electrochemical Synthesis and Structural Characterization of the One‐ Dimensional Chain Compound (Et4N)2(As2Te5) (I) and the Tellurido Arsenate (Me4N)4(As4Te6)×2en (II). (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
From syllables to words: EEG studies on infants' language perception and language acquisition with a cochlear implant (2019)

We still know little about what infants and young children perceive after receiving a cochlear implant and how this influences subsequent language acquisition. In three longitudinal EEG studies and one follow-up study we investigate whether and when certain linguistic features are perceived via the implant in relation to the timeline of the actual word acquisition process.
An Optical Technique to Produce Embedded Quantum Structures in Semiconductors (2023)

The performance of a semiconductor quantum-electronic device ultimately depends on the quality of the semiconductor materials it is made of and on how well the device is isolated from electrostatic fluctuations caused by unavoidable surface charges and other sources of electric noise. Current technology to fabricate quantum semiconductor devices relies on surface gates which impose strong limitations on the maximum distance from the surface where the confining electrostatic potentials can be engineered. Surface gates also introduce strain fields which cause imperfections in the semiconductor crystal structure. Another way to create confining electrostatic potentials inside semiconductors is by means of light and photosensitive dopants. Light can be structured in the form of perfectly parallel sheets of high and low intensity which can penetrate deep into a semiconductor and, importantly, light does not deteriorate the quality of the semiconductor crystal. In this work, we employ these important properties of structured light to form metastable states of photo-sensitive impurities inside a GaAs/AlGaAs quantum well structure in order to create persistent periodic electrostatic potentials at large predetermined distances from the sample surface. The amplitude of the light-induced potential is controlled by gradually increasing the light fluence at the sample surface and simultaneously measuring the amplitude of Weiss commensurability oscillations in the magnetoresistivity.
THE MECHANISM OF IMPROVING THE FROST RESISTANCE BY ADDING MICROSPHERES (2015)

中空微小球を配合した硬化体の空隙特性について、AE剤を配合した場合と比較検討した。中空微小球によって導入した空気量相当分とセメント硬化体の圧縮強度に一次比例的な負の相関が確認され、中空微小球の体積が空隙としてみなせることを確認した。アルキメデス法にて空隙量を測定した場合には、中空微小球による空隙が測定されなかったが、水銀圧入法による測定では、導入した空気量相当分とセメント硬化体中の空隙量には比例関係が認められ、同様にインクボトル空隙量とも比例関係が確認された。高圧下で中空微小球はインクボトル型の空隙として振舞い、硬化体内部に発生する圧力の上昇を緩和し、耐凍害性に寄与するものと推察した。
Electroconvulsive therapy in bipolar depression – effectiveness and prognostic factors (2019)

Electroconvulsive therapy for bipolar depression was associated with very high response rates. The strongest prognostic factors were higher age, absence of comorbid obsessive-compulsive disorder or personality disorder, and less prior pharmacologic treatment.
Tunable absorptive bandstop filter with an ultra-broad upper passband (2017)

This paper presents a new broadband external coupling structure for tunable evanescent-mode cavity resonator-based bandstop filters. This coupling method has low levels of parasitic reactances, which when combined with the wide spurious-free range of evansecent-mode cavities enables the implementation of a 3 to 6 GHz tunable bandstop filter which has a measured upper passband with less than 3-dB of insertion loss up to 28.5 GHz.
Systemic Versus CNS Delivery Of MOE Antisense Oligonucleotide to Correct Defective Splicing in a Severe Mouse Model of Spinal Muscular Atrophy (2011)

Spinal Muscular Atrophy (SMA) is a genetic disease characterized by progressive degeneration of motor neurons in the spinal cord, leading to muscle weakness and atrophy. SMA is caused by deletion or mutations in the Survival-of-motor neuron(SMN1) gene. The paralogous SMN2 gene, present in one or more copies in all SMA patients, attenuates SMA severity, but expresses low levels of full-length SMN protein, due to alternative splicing that results in inefficient inclusion of exon 7. Increasing SMN2 exon 7 inclusion to express more full-length, functional SMN protein in motor neurons is a promising approach to treat SMA. We previously reported a 2′-O-(2-methoxyethyl) (MOE) phosphorothioate 18mer antisense oligonucleotide (ASO) that targets a splicing-repressor binding site in intron 7. By preventing binding of the repressor (hnRNP A1), the ASO promotes efficient SMN2exon 7 inclusion in liver and kidneys of transgenic mice after systemic administration. It is generally believed that SMN restoration in spinal-cord motor neurons is necessary and sufficient to cure SMA. However, cardiac defects were recently reported in both severe SMA patients and mouse models. These defects might reflect autonomic dysfunction; alternatively, they could be caused by factors outside the CNS. In the latter scenario, peripheral SMN restoration might be necessary for therapy.We sought to compare the therapeutic effects of systemic restoration versus CNS restoration of the SMN protein in neonates of a severe mouse model (Smn-/-; hSmn2+/0) that survives 10 days. To increase SMN levels in the CNS, we directly injected the ASO into a cerebral lateral ventricle at postnatal day 1 (P1); to increase SMN levels in peripheral tissues, we subcutaneously injected the ASO into P0-P3 neonates. Surprisingly, neonatal systemic administration robustly rescued SMA mice, and was much more effective than intracerebroventricular administration alone; a single neonatal subcutaneous injection extended the median lifespan by 25-fold. The majority of the rescued mice had no motor defects, and showed increased motor-neuron numbers and normal neuromuscular-junction morphology. Remarkably, some of the SMA mice treated systemically at P0-P3 have so far survived for 1 year and are still vigorous. Our data not only demonstrate an effective drug candidate, but also reveal the importance of SMN restoration outside the CNS for treatment of severe SMA. The mechanisms underlying the striking effectiveness of SMN restoration in peripheral tissues will be discussed.