gebhart/patrepeval huggingface dataset:
Fiat lux: a fluorescent lamp digital transceiver (1998)

The prevalence of electric discharge illumination has led the authors to consider ways to use discharge lamps for communication. This paper describes an optical transceiver system which transmits by modulating the lamp arc. The prototype power electronic lamp ballast uses a pulse-frequency modulation scheme which ensures no perceptible flicker.
ChemInform Abstract: Optical Detection and Manipulation of Single Molecules in Room‐ Temperature Solutions (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Organic ligand-receptor interactions between cucurbituril and alkylammonium ions (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOrganic ligand-receptor interactions between cucurbituril and alkylammonium ionsWilliam L. Mock and Neng Yang. ShihCite this: J. Am. Chem. Soc. 1988, 110, 14, 4706–4710Publication Date (Print):July 1, 1988Publication History Published online1 May 2002Published inissue 1 July 1988https://pubs.acs.org/doi/10.1021/ja00222a031https://doi.org/10.1021/ja00222a031research-articleACS PublicationsRequest reuse permissionsArticle Views1045Altmetric-Citations172LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Towards reconstruction of embedded objects with multiple speckle images for medical diagnostics (2005)

A new method of seeing objects hidden in scattering medium from multiple speckle images is demonstrated. The entire noisy images from lens array are digitally processed to obtain the desired image of the hidden objects.
Data from Merkel Cell Polyomavirus Infection, Large T Antigen, Retinoblastoma Protein and Outcome in Merkel Cell Carcinoma (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Merkel cell carcinoma (MCC) is rare skin cancer that is often associated with Merkel cell polyomavirus (MCPyV) infection. Polyomaviruses repress tumor suppressor proteins, thus influencing cell-cycle progression, but the effect of MCPyV on the key cell-cycle regulating proteins is poorly understood.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; We evaluated expression of the MCPyV large T-antigen (LTA), Ki-67, and the key putative tumor suppressor proteins, the retinoblastoma protein (RB and phospho-RB) and p53, and their regulatory proteins (cyclin D1, cyclin E, p16, p21, p27, and MDM2) by using immunohistochemistry from tumors of 91 MCC patients identified from a population-based nationwide cohort. Tumor MCPyV DNA was measured by using quantitative PCR, and &lt;i&gt;TP53&lt;/i&gt; mutations were identified with sequencing.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; MCPyV LTA expression was strongly associated with presence of MCPyV DNA in tumor, and it was almost invariably associated with tumor RB expression (&lt;i&gt;P&lt;/i&gt; &lt; 0.0001 for both comparisons). Both MCC LTA and RB expression were strongly associated with favorable MCC-specific and overall survival in univariable analyses (&lt;i&gt;P&lt;/i&gt; ≤ 0.01 for all four analyses). Presence of MCPyV LTA was also associated with the female gender, the intermediate type of tumor histology, location of the tumor in a limb, cell proliferation rate, and absence of p53 expression. &lt;i&gt;TP53&lt;/i&gt; mutations were detected only in MCPyV DNA–negative tumors.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; MCPyV DNA–positive MCC has several clinical and molecular features that differ from MCPyV DNA-negative cancers. MCPyV-associated MCCs express RB, but may not harbor &lt;i&gt;TP53&lt;/i&gt; mutations. These findings provide further support that MCPyV causes the majority of MCCs. &lt;i&gt;Clin Cancer Res; 17(14); 4806–13. ©2011 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
684. Long-Term, Multilineage Engraftment of Zinc Finger Nuclease-Edited Hematopoietic Stem Cells in Nonhuman Primates (2015)

Background: Nuclease-mediated gene editing in hematopoietic stem cells (HSCs) holds great promise for diseases including HIV infection and hemoglobinopathies, but little information is available regarding the feasibility of this approach in large animal models. To better evaluate the function of HSCs following gene editing, we have engineered cells with disrupted CCR5 alleles and assessed engraftment following autologous transplant in the pigtailed macaque, M. nemestrina. Disrupted CCR5 alleles in this model should directly protect against infection with simian/human immunodeficiency virus (SHIV). We are evaluating the extent to which CCR5-disrupted cell progeny engraft in macaques, and testing whether these cells impede infection by SHIV. Methods: Zinc Finger Nucleases (ZFNs) are used to target the CCR5 locus in macaque HSCs. Engraftment and persistence of these autologous stem cells, and stem cell-derived lymphoid and myeloid cells, are measured ex vivo and in vivo. Animals are challenged with SHIV virus containing an HIV envelope; to approximate the status of an HIV+ patient, three-drug combination antiretroviral therapy (cART) is initiated following viral set point. Animals reach undetectable levels of plasma viremia prior to autologous transplant with gene-edited cells. Results: CCR5 targeting experiments yield up to 60% gene disruption in CD34+ cells ex vivo, translating to approximately 5% steady state bulk disruption in vivo. Gene-disrupted cells demonstrate long-term, multilineage engraftment in macaques, including comparable levels of disruption in CD3+, CD20+, CD14+, and granulocyte subsets. We also observe biallelic disruption of CCR5 in colony forming assays. Importantly, this approach is equally feasible in SHIV-naïve and in SHIV-infected, cART-suppressed animals. During robust SHIV replication, our preliminary data suggest that CCR5-deleted cells undergo positive selection in vivo. Conclusions: This is the first demonstration of successful long-term multilineage engraftment of ZFN-edited HSCs in a NHP transplantation model. The CCR5 gene editing/HSCT strategy presented here results in robust levels of target gene disruption in vivo, yet does not impair HSC engraftment or differentiation. CCR5-deleted cells can undergo positive selection following challenge with SHIV. Our model enables the evaluation of novel therapeutic approaches in a number of infectious and genetic diseases including HIV infection. Specifically, these results are applicable not only in the context of acute HIV exposure, but also in the clinically relevant setting of pre-existing latent HIV infection.
Study of 1340 nm Continuous Laser Invasiveness on 28 nm Advanced Technologies (2016)

Abstract This paper presents a study about the invasiveness of 1340 nm continuous wave laser used for electrical failure analysis on 28 nm advanced technologies. It underlines the potential laser-induced degradation for deep submicron technologies that could jeopardize analysis results by modifying physical and chemical properties at substructure level. The impact of laser power on transistor morphology and electrical behavior is studied and the results of this study enable us to setup safe experimental conditions.
Integrated Near-Field Thermophotovoltaic Device Overcoming Blackbody Limit (2021)

Near-field thermal radiation transfer overcoming the blackbody limit has attracted significant attention in recent years owing to its potential for drastically increasing the output power and conversion efficiency of thermophotovoltaic (TPV) power generation systems. Here, we experimentally demonstrate a one-chip near-field TPV device overcoming the blackbody limit, which integrates a 20-μm-thick Si emitter and an InGaAs PV cell with a subwavelength gap (<140 nm). The device exhibits a photocurrent density of 1.49 A/cm2 at 1192 K, which is 1.5 times larger than the far-field limit at the same temperature. In addition, we obtain an output power of 1.92 mW and a system efficiency of 0.7% for a 1 mm2 device, both of which are 1 to 2 orders of magnitude greater than those of the previously reported near-field systems. Detailed comparisons between the simulations and experiments reveal the possibility of a system efficiency of >35% in the up-scaled device, thus demonstrating the potential of our integrated near-field TPV device for practical use in the future.
Optimizing the Tradeoff between Signaling and Reconfiguration: A Novel Bi-Criteria Solution Approach for Revising Tracking Area Design (2009)

Improving the tracking areas (TA) configuration over time to reduce signaling overhead is vital for location management of Long Term Evolution networks. The user location and mobility patterns have the tendency to change over time, and consequently the TA layout needs to be revised. A TA reconfiguration would cause service interruption and "cost". Hence there will always be a tradeoff between the total signaling overhead and the reconfiguration cost. In this paper a genetic algorithm together with local search are applied to this bi-objective problem. Unlike previous methods, our approach does not need to weight together the two objective functions. Instead, the algorithm is designed to deliver various Pareto-optimal solutions in a single run. Computational experiments are presented for a realistic TA planning scenario of Lisbon city. The results illustrate the ability of the approach to address the primary concern in decision making of an operator - benefit versus cost, by means of providing multiple reconfiguration choices with various levels of trade-off between the two factors.
Aggregation-driven, re-entrant isotropic phase in a smectic liquid crystal material (2016)

An azobenzene-core chiral mesogen designed for a photoactive ferroelectric liquid crystal system with switchable polarisation displays a highly unusual phase sequence, with a re-entrant, optically isotropic, fluid phase found below smectic phases in mixtures with high enantiomeric purity. The re-entrant isotropic phase is found on the basis of X-ray scattering and freeze-fracture transmission electron microscopy experiments not to be a cubic or other highly ordered phase but instead a translationally disordered liquid. The material also forms a gel under a wide range of concentrations in 50:50 ethanol/chloroform solutions. Ultraviolet/visible and infrared spectroscopy and quantum chemistry calculations suggest that the primary unit in the re-entrant isotropic and gel phases is a dimer composed of molecules crossed by about 90°, which hinders the formation of crystal phases and forms tubules of helical aggregates in the gel phase.
Analysis of isothermal spinning of liquid-crystalline polymers (1993)

In this paper we use the constitutive equation of Bhave et al. (1993) for rod-like, liquid-crystalline polymer solutions to analyze the isothermal, steady-state spinning of these liquids in order to understand the evolution of microstructure, predict the velocity and normal stress distributions in the filament, and examine the effect of different upstream microstructural conditions. Our analysis shows that in contrast to fiber spinning models of isotropic liquids, the velocity, structure, and stress profiles are sensitive to the choice of initial conditions. In addition we have investigated the impact of the closure approximation used in the constitutive equation of Bhave et al. on the fiber spinning problem by solving the equation for the distribution function directly; only slight changes are seen in the velocity and stress profiles. An apparent elongational viscosity defined as the ratio of normal stress difference to strain rate at the takeup compares very well with the true elongational viscosity η̄ for the model, thereby suggesting that fiber spinning flows can be used to determine η̄ for liquid-crystalline polymer solutions. Model predictions of the velocity and stress agree well with data obtained by Prilutski (1984) for HPC/acetic acid solutions. Finally, we present a linear stability analysis of the spinning problem to show the impact of viscoelasticity, inertia, gravity, and surface tension on the onset of draw resonance instabilities. The neutral stability curves obtained for dominant viscoelastic forces reflect trends in the apparent elongational viscosity. Model predictions are in qualitative agreement with the draw resonance data reported by Prilutski.
Calcificaciones cardiovasculares: factores etiológicos implicados (2005)

Las calcificaciones cardiovasculares afectan a un importante sector de la población y pueden ser causa de serios problemas de salud. Así, alteran la flexibilidad de las arterias y facilitan la trombosis y su ruptura. Las calcificaciones valvulares dan lugar a diversos desórdenes que acaban en fallo cardíaco. En todos los casos la fase mineral corresponde a fosfatos cálcicos (fundamentalmente hidroxiapatita) y en las arterias puede localizarse en la media o en la íntima. En las válvulas cardíacas naturales, la calcificación suele comenzar en la parte interna, mientras que en las prostéticas es superficial. El mecanismo general del proceso de calcificación implica la existencia de una lesión previa (debida a agentes citotóxicos, hipercolesterolemia, insuficiencia renal terminal, edad avanzada, hiperlipemia, obesidad, diabetes, infecciones bacterianas) que actúa como inductora (nucleante heterogéneo) de la calcificación. Si los factores represores (inhibidores de la cristalización, moduladores de la acción celular) no poseen capacidad suficiente para impedir las primeras fases del proceso de calcificación, acabarán formándose placas calcificadas que ya será imposible eliminar sin utilizar cirugía. Puede concluirse, por lo tanto, que la prevención es fundamental para evitar el desarrollo de calcificaciones cardiovasculares, siendo necesario tanto identificar los factores promotores, relacionarlos con el tipo de calcificación y estudiar las vías de su control, como identificar los factores inhibidores de la cristalización y estudiar sus efectos. Cardiovascular calcifications affect to a wide sector of the population and can cause serious health problems. Thus, they alter arterial flexibility and facilitate thrombosis and arterial rupture. Calcification of heart valves generates several disorders responsible for heart failure. In all cases the mineral phase corresponds to calcium phosphates (fundamentally hydroxyapatite) that can be located in the media or intimal layers. In native heart valves, calcification is usually generated in the internal part, while in the bioprosthetic is superficial. The basic mechanism of the calcification process implies the existence of an underlying lesion (due to cytotoxic agents, hypercholesterolemia, endstage renal disease, ageing, hyperlipidaemia, obesity, diabetes, bacterial infections) that acts as inducer (heterogeneous nucleant) of the calcification. If the repressive factors (crystallization inhibitors, modulators of cellular action) are not capable enough to avoid the first steps of the calcification process, calcified plaques will developed and will become impossible to eliminate them without surgery. Therefore, it can be concluded that prevention is fundamental to avoid the development of cardiovascular calcifications, being necessary: 1) to identify the trigger factors, to relate them with the type of calcification, and to study the ways of their control, and 2) to identify the crystallization inhibitor factors and to study their effects.
Mouse Urinary Biomarkers Provide Signatures of Maturation, Diet, Stress Level, and Diurnal Rhythm (2010)

Body fluids such as urine potentially contain a wealth of information pertaining to age, sex, social and reproductive status, physiologic state, and genotype of the donor. To explore whether urine could encode information regarding environment, physiology, and development, we compared the volatile compositions of mouse urine using solid-phase microextraction and gas chromatography-mass spectrometry (SPME-GC/MS). Specifically, we identified volatile organic compounds (VOCs) in individual urine samples taken from inbred C57BL/6J-H-2(b) mice under several experimental conditions-maturation state, diet, stress, and diurnal rhythms, designed to mimic natural variations. Approximately 1000 peaks (i.e., variables) were identified per comparison and of these many were identified as potential differential biomarkers. Consistent with previous findings, we found groups of compounds that vary significantly and consistently rather than a single unique compound to provide a robust signature. We identified over 49 new predictive compounds, in addition to identifying several published compounds, for maturation state, diet, stress, and time-of-day. We found a considerable degree of overlap in the chemicals identified as (potential) biomarkers for each comparison. Chemometric methods indicate that the strong group-related patterns in VOCs provide sufficient information to identify several parameters of natural variations in this strain of mice including their maturation state, stress level, and diet.
Temperature dependence of radiative and non-radiative decay in the luminescence of one-dimensional pyridinium lead halide hybrids (2023)

The photoluminescence properties of organic-inorganic pyridinium lead bromide [(pyH)PbBr<sub>3</sub>] and iodide [(pyH)PbI<sub>3</sub>] compounds were investigated as a function of temperature. The inorganic substructure consists of face-sharing chains of PbX<sub>6</sub> octahedra. Diffuse reflectance spectra of the compounds show low energy absorption features consistent with charge transfer transitions from the PbX<sub>3</sub> chains to the pyridinium cations. Both compounds display extremely weak luminescence at room temperature that becomes strongly enhanced upon cooling to 77 K. Broad, featureless low energy emission (<i>λ</i><sub>em</sub> > 600 nm) in both compounds have large Stokes shifts [1.1 eV for (pyH)PbBr<sub>3</sub> and 0.46 eV for (pyH)PbI<sub>3</sub>] and are assigned to transitions from self-trapped excitons on the inorganic chains whereas emission at higher energy in (pyH)PbBr<sub>3</sub> (<i>λ</i><sub>em</sub> = 450 nm) is assigned to luminescence from a free exciton state. Analysis of data from temperature-dependent luminescence intensity measurements gives activation energies (<i>E</i><sub>a</sub>) for non-radiative decay of the self-trapped excitons in (pyH)PbBr<sub>3</sub> and (pyH)PbI<sub>3</sub>, (<i>E</i><sub>a</sub> = 0.077 eV and 0.103 eV, respectively) and for the free exciton in (pyH)PbBr<sub>3</sub> (<i>E</i><sub>a</sub> = 0.010 eV). Analysis of temperature dependent luminescence lifetime data indicates another non-radiative decay process in (pyH)PbI<sub>3</sub> at higher temperatures (<i>E</i><sub>a</sub> = 0.17 eV). A large increase in the luminescence lifetime of (pyH)PbI<sub>3</sub> below 80 K is consistent with thermalization between triplet sublevels. Analysis of the luminescence power dependence for (pyH)PbI<sub>3</sub> shows superlinear response suggestive of quenching by static traps.
Traffic characterization and its applications to ATM network design (1996)

The integration of data, voice, and video services in the emerging B-ISDN/ATM networks presents new challenges in traffic management. A clear understanding of the traffic characteristics of each of these services is necessary in order to guarantee the Quality of Service (QoS) to each traffic type. In this dissertation we develop a new descriptive model of traffic characterization process along with algorithms and tools to automate it. The use of sampling techniques and their effect on protocol distributions is studied and integrated as part of the traffic characterization process. In addition, we present several measured traffic model of Wide Area Network TCP/IP traffic collected at The junction of the Pennsylvania State University Data Backbone to the Internet. Finally, we apply the various empirical traffic modelling to solve some ATM traffic management problems such as queue and memory management, and connection admission control.
MP46-18 ANTIBIOTIC-RESISTANT UROPATHOGENS FORM BIOFILMS PREDOMINANTLY ON DISTAL AND LUMINAL ASPECTS OF CATHETERS AND ARE INHIBITED BY A NOVEL CETYLPYRIDINIUM CHLORIDE-BASED FORMULATION (2020)

Endourological surgeons were divided into a surgical hand hygiene group (n [ 171) and a regular hygiene group (n [ 133). No differences were observed between the groups in terms of patient history, namely, the prevalence of organ infection, diabetes, history of smoking, steroid therapy, obesity, or malnutrition. Similarly, no differences were observed in the patient performance status, type of procedure, and inflammatory parameters of serum and urine between the groups. Univariate and multivariate analyses showed no significant differences in f-UTI-related factors, such as postoperative fever, bacteriuria, inflammatory markers, and the incidence of sepsis.
Opportunistic Polarization-Matching for Multiuser Polarized MISO Downlink (2016)

Channel imperfections, obstacles, and the unpredictable movements of user equipment can create polarization-mismatch at the receiving antenna, which decreases the power of the received signal in practical wireless communications. In such environments, performance can be improved by opportunistic polarization-matching via dual-polarized (DP) transmitters for limited feedback systems. In this letter, we demonstrate the performance enhancement obtained from opportunistic polarization-matching between a DP transmitter and randomly rotated single-polarized (SP) receivers via a proposed DP multiple-input and SP single-output spatial channel model.
Description of quadratic optical nonlinearities for transition-metal organometallic chromophores using an SCF-LCAO MECI formalism (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDescription of quadratic optical nonlinearities for transition-metal organometallic chromophores using an SCF-LCAO MECI formalismDavid R. Kanis, Mark A. Ratner, and Tobin J. MarksCite this: J. Am. Chem. Soc. 1990, 112, 22, 8203–8204Publication Date (Print):October 1, 1990Publication History Published online1 May 2002Published inissue 1 October 1990https://doi.org/10.1021/ja00178a075RIGHTS & PERMISSIONSArticle Views122Altmetric-Citations69LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (302 KB) Get e-Alerts Get e-Alerts