gebhart/patrepeval huggingface dataset:
Handling Asymmetry in Gain in Directional Antenna Equipped Ad Hoc Networks (2006)

The deployment of traditional higher layer protocols (especially the IEEE 802.11 MAC protocol at the MAC layer) with directional antennae could lead to problems from an increased number of collisions; this effect is primarily seen due to three specific effects: (i) an increase in the number of hidden terminals; (ii) the problem of deafness and, (iii) a difficulty in determining the locations of neighbors. In this work we propose a new MAC protocol that incorporates circular RTS and CTS transmissions. We show that the circular transmission of the control messages helps avoid collisions of both DATA and ACK packets from hidden terminals. Our protocol intelligently determines the directions in which the control messages ought to be transmitted so as to eliminate redundant transmissions in any given direction. We perform extensive simulations and analyze the obtained results in order to compare our scheme with previously proposed protocols that have been proposed for use in directional antenna equipped ad hoc networks. Our simulation results clearly demonstrate the benefits of incorporating both circular RTS and CTS messages in terms of the achieved aggregate throughput.
Reduction of Switching Frequency for the Semi-Full-Bridge Submodule Using Alternative Bypass States (2018)

As regards modular multilevel converter submodules, a different number of switches may be involved in the transitions between voltage levels depending on the submodule type and choice of switching states. In this paper, an investigation of the average switching frequency associated with different choices of bypass states is performed for the semi-full-bridge submodule. Theoretical considerations and simulation results show that the average switching frequency per device can be halved by using the proposed alternative bypass state. Moreover, the switching losses can be reduced by up to 60%. Finally, a comparative study with the full-bridge submodule has been conducted.
A proximal gradient algorithm for tracking cascades over networks (2014)

Many real-world processes evolve in cascades over networks, whose topologies are often unobservable and change over time. However, the so-termed adoption times when for instance blogs mention popular news items are typically known, and are implicitly dependent on the underlying network. To infer the network topology, a dynamic structural equation model is adopted to capture the relationship between observed adoption times and the unknown edge weights, while accounting also for external (non-topological) perturbations. Assuming a slowly time-varying topology and leveraging the sparse connectivity inherent to social networks, edge weights are estimated by minimizing a sparsity-regularized exponentially-weighted least-squares criterion. To this end, a solver is developed by leveraging (pseudo) real-time sparsity-promoting proximal gradient iterations. Numerical tests with real cascades of online media demonstrate the effectiveness of the novel algorithm in unveiling sparse dynamically-evolving topologies.
Morphologies of Planar Polyelectrolyte Brushes in a Poor Solvent: Molecular Dynamics Simulations and Scaling Analysis (2009)

Using molecular dynamics simulations and scaling analysis, we study the effect of the solvent quality for the polymer backbone, the strength of the electrostatic interactions, the chain degree of polymerization, and the brush grafting density on conformations of the planar polyelectrolyte brushes in salt-free solutions. Polyelectrolyte brush forms: (1) vertically oriented cylindrical aggregates (bundles of chains), (2) maze-like aggregate structures, or (3) thin polymeric layer covering a substrate. These different brush morphologies appear as a result of the fine interplay between electrostatic and short-range monomer-monomer interactions. The brush thickness shows nonmonotonic dependence on the value of the Bjerrum length. It first increases with the increasing value of the Bjerrum length, and then it begins to decrease. This behavior is a result of counterion condensation within a brush volume.
Two-Dimensional Label-Free Affinity Analysis of Tumor-Specific CD8 T Cells with a Biomimetic Plasmonic Sensor (2018)

The screening and analysis of T cells functional avidity for specific tumor-associated antigens is crucial for the development of personalized immunotherapies against cancer. The affinity and kinetics of a T cell receptor (TCR) binding to the peptide-major histocompatibility complex (pMHC), expressed on tumor or antigen-presenting cells, have shown major implications in T cell activation and effector functions. We introduce an innovative methodology for the two-dimensional affinity analysis of TCR-pMHC in a label-free configuration by employing a multiparametric Surface Plasmon Resonance biosensor (MP-SPR) functionalized with artificial cell membranes. The biomimetic scaffold created with planar lipid bilayers is able to efficiently capture the specific and intact tumor-specific T cells and monitor the formation of the immunological synapse in situ. We have achieved excellent limits of detection for in-flow cell capturing, up to 2 orders of magnitude below the current state-of-the-art for plasmonic sensing. We demonstrate the accuracy and selectivity of our sensor for the analysis of CD8<sup>+</sup> T cells bioengineered with TCR of incremental affinities specific for the HLA-A0201/NY-ESO-I<sub>157-165</sub> pMHC complex. The study confirmed the significance of providing a biomimetic microenvironment, compared to the traditional molecular analysis, and showed fine agreement with previous results employing flow cytometry. Our methodology is reliable and versatile; thus, it can be applied to more sophisticated photonic and nanoplasmonic technologies for the screening of multiple cell types and boost the development of novel treatments for cancer.
Supplementary Table 3 from MYC Phosphorylation at Novel Regulatory Regions Suppresses Transforming Activity (2023)

&lt;p&gt;XLS file, 319K, Expression array analysis of MCF10A 3D cultures at 4 days.&lt;/p&gt;
Equivalent Consumption Minimization Strategy Based on Belt Drive System Characteristic Maps for P0 Hybrid Electric Vehicles (2023)

A P0 system is used in hybrid automobiles to improve engine economy and performance. An essential element of the P0 system for effectively transmitting power to the drive train is the belt drive system (BDS). The features of electric machine (EM) and internal combustion engines (ICE) are taken into account by standard energy management systems, such as the equivalent consumption minimization strategy (ECMS). In order to maximize the effectiveness of the P0 system, this work provides a novel formulation of the ECMS, which considers the power loss map of the BDS in addition to the characteristic maps of EM and ICE. A test bench is built up to characterize the BDS, and it is verified using an open-loop Hardware in the Loop (HIL) in the WLTP driving cycle. To find the most appropriate equivalence factors for the ECMS, which would ordinarily be tuned through trial and error, a genetic algorithm (GA) is used. With regard to the standard ECMS, the proposed methodology intends to reduce fuel usage and CO2 emissions. Two belts in BDS were tested in the WLTP to achieve CO2 savings of 1.1 and 0.9 [g/km], indicating the enhancement of system performance by using the BDS power loss maps in ECMS.
Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test (2017)

PurposeGenetic testing is an integral diagnostic component of pediatric medicine. Standard of care is often a time-consuming stepwise approach involving chromosomal microarray analysis and targeted gene sequencing panels, which can be costly and inconclusive. Whole-genome sequencing (WGS) provides a comprehensive testing platform that has the potential to streamline genetic assessments, but there are limited comparative data to guide its clinical use.MethodsWe prospectively recruited 103 patients from pediatric non-genetic subspecialty clinics, each with a clinical phenotype suggestive of an underlying genetic disorder, and compared the diagnostic yield and coverage of WGS with those of conventional genetic testing.ResultsWGS identified diagnostic variants in 41% of individuals, representing a significant increase over conventional testing results (24%; P = 0.01). Genes clinically sequenced in the cohort (n = 1,226) were well covered by WGS, with a median exonic coverage of 40 × ±8 × (mean ±SD). All the molecular diagnoses made by conventional methods were captured by WGS. The 18 new diagnoses made with WGS included structural and non-exonic sequence variants not detectable with whole-exome sequencing, and confirmed recent disease associations with the genes PIGG, RNU4ATAC, TRIO, and UNC13A.ConclusionWGS as a primary clinical test provided a higher diagnostic yield than conventional genetic testing in a clinically heterogeneous cohort.
Functional characterization and differential coactivation patterns of two cytoarchitectonic visual areas on the human posterior fusiform gyrus (2013)

The ventral stream of the human extrastriate visual cortex shows a considerable functional heterogeneity from early visual processing (posterior) to higher, domain-specific processing (anterior). The fusiform gyrus hosts several of those "high-level" functional areas. We recently found a subdivision of the posterior fusiform gyrus on the microstructural level, that is, two distinct cytoarchitectonic areas, FG1 and FG2 (Caspers et al., Brain Structure & Function, 2013). To gain a first insight in the function of these two areas, here we studied their behavioral involvement and coactivation patterns by means of meta-analytic connectivity modeling based on the BrainMap database (www.brainmap.org), using probabilistic maps of these areas as seed regions. The coactivation patterns of the areas support the concept of a common involvement in a core network subserving different cognitive tasks, that is, object recognition, visual language perception, or visual attention. In addition, the analysis supports the previous cytoarchitectonic parcellation, indicating that FG1 appears as a transitional area between early and higher visual cortex and FG2 as a higher-order one. The latter area is furthermore lateralized, as it shows strong relations to the visual language processing system in the left hemisphere, while its right side is stronger associated with face selective regions. These findings indicate that functional lateralization of area FG2 relies on a different pattern of connectivity rather than side-specific cytoarchitectonic features.
Switching Characteristics of SiC-MOSFET and SBD Power Modules (2006)

Prototype SiC power modules are fabricated using our class 10 A, 1.2 kV SiC-MOSFETs and SiC-SBDs, and their switching characteristics are evaluated using a double pulse method. Switching waveforms show that both overshoot and tail current, which induce power losses, are suppressed markedly compared with conventional Si-IGBT modules with similar ratings. The total switching loss (MOSFET turn-ON loss, turn-OFF loss and SBD recovery loss) of SiC power modules is measured to be about 30% of that of Si-IGBT modules under the generally-used switching condition (di/dt ~250A/μs). The three losses of SiC modules decrease monotonically with a decrease in gate resistance, namely switching speed. The result shows the potential of unipolar device SiC power modules.
GROUND BASED SENSOR INTEGRATION FOR SPATIAL DATA ACQUISITION AND DATABASE DEVELOPMENT (2000)

Recent several years, Photogrammetry, GPS and their related technologies have been advanced. These technologies can be integrated under GIS. However GIS has an unsolved problem how cost-effective and accurate geo-data can generate. In this paper, the authors describe on the development of a spatial data acquisition tool so called mobile system by combining ground-based sensors in order to generate cost-effective geo-data and its database construction for distribution of obtained information. Our final goal is to identify the both of specific land condition and distribution as three-dimensional data. Three-dimensional measurement can be introduced by photogrammetric approach. As the future study, the authors are planning to use the developed tool at an actual field information mapping in Southeast Asian study site.
Highly efficient nonlinearity reduction in silicon-on-insulator waveguides using vertical slots (2010)

Vertical slots are used to reduce the nonlinearity of silicon-on-insulator waveguides. In properly designed slot waveguides, approximately 50% of the optical power can be confined in the air-slot and air-cladding region. Compared with a strip waveguide, a factor greater than 15 times more reduction in the real part of nonlinear coefficient can be achieved in the 100-nm wavelength range. In addition, vertical-slot waveguides exhibit large negative chromatic dispersion, which will induce phase mismatch and further suppress nonlinear parametric effects.
Digital Rights Management for Consumer Devices (2004)

This chapter outlines the history of this effort and concludes with some discussion of a possible future direction. It focuses on the technical aspects of specific content protection schemes. Digital rights management in consumer electronics devices, to date, is about restricting unauthorized copies. The chapter describes MacroVision works in the analog domain and requires no secrets and no device license, because it is based on fundamental differences between Television and Video cassette recorders. The Content Scrambling System works by assigning each device manufacturer a single key. Divx was implemented by requiring the player to have a phone connection to a clearinghouse and periodically to call and report usage. Called Digital Transmission Content Protection, it is available on Firewire, on the Universal Serial Bus, and on any transmission technology that supports Transmission Control Protocol/Internet Protocol. Ideally, the personal digital domain content protection should be completely transparent to the average consumer.
Rewiring the Wax Ester Production Pathway of Acinetobacter baylyi ADP1 (2014)

Wax esters are industrially relevant high-value molecules. For sustainable production of wax esters, bacterial cell factories are suggested to replace the chemical processes exploiting expensive starting materials. However, it is well recognized that new sophisticated solutions employing synthetic biology toolbox are required to improve and tune the cellular production platform to meet the product requirements. For example, saturated wax esters with alkanol chain lengths C12 or C14 that are convenient for industrial uses are rare among bacteria. Acinetobacter baylyi ADP1, a natural producer of wax esters, is a convenient model organism for studying the potentiality and modifiability of wax esters in a natural host by means of synthetic biology. In order to establish a controllable production platform exploiting well-characterized biocomponents, and to modify the wax ester synthesis pathway of A. baylyi ADP1 in terms product quality, a fatty acid reductase complex LuxCDE with an inducible arabinose promoter was employed to replace the natural fatty acyl-CoA reductase acr1 in ADP1. The engineered strain was able to produce wax esters by the introduced synthetic pathway. Moreover, the fatty alkanol chain length profile of wax esters was found to shift toward shorter and more saturated carbon chains, C16:0 accounting for most of the alkanols. The study demonstrates the potentiality of recircuiting a biosynthesis pathway in a natural producer, enabling a regulated production of a customized bioproduct. Furthermore, the LuxCDE complex can be potentially used as a well-characterized biopart in a variety of synthetic biology applications involving the production of long-chain hydrocarbons.
Structural analysis and generation of synthetic digital circuits with memory (2001)

One of the most difficult aspects of experimental reconfigurable architecture or computer-aided design (CAD) tool research is obtaining sufficiently large benchmark circuits. One approach to obtaining such circuits is to generate them stochastically. Current circuit generators construct combinational and sequential logic circuits. Many of today's devices, however, are being used to implement entire systems, and often these systems contain on-chip storage. This paper describes a circuit generator that constructs circuits containing significant amounts of memory. To ensure the circuits are realistic, we have performed a detailed structural analysis of such circuits; this analysis is also described in this paper.
An Efficient Synthesis of Mimetics of Neamine for RNA Recognition (2001)

As mimetics of neamine, several 4-heterocyclic 2-deoxystreptamine derivatives were chemically synthesized for RNA recognition. Conversion of 4-methylthiomethyl-5,6-di-O-acetyl-diazido-2-deoxystreptamine to the 4-chloromethyl derivative followed by reactions with different nuclophilic reagents gave the 4-heterocyclic 2-deoxystreptamine derivatives in satisfactory yields.
Time delay, crosstalk and repeater insertion models for high performance SoC's (2003)

Using a new physical model for the transient response of a distributed RLC interconnect with a capacitive load, novel compact expressions have been derived for: (1) the time delay, (2) the peak crosstalk for coupled lines, (3) the optimum number and size of repeaters, and (4) the time delay for repeater-inserted distributed RC and RLC lines. For practical ranges of line parameters, the maximum error between the compact models for time delay and crosstalk, and HSPICE simulations are 2% and 10% respectively. These new models are used to define a design space that illustrates a novel trade-off between number of repeaters and wire cross-section to achieve specified delay and crosstalk targets. For a 3 cm long interconnect, inserting 8 repeaters decreases peak crosstalk by 51% and wire cross sectional area by 83% without increasing the time delay, compared to a design without repeaters.
Ketimin‐Komplexe aus 1‐Diazo‐1‐phenyläthan (1974)

Abstract 1‐Diazo‐1‐phenylethan ( 2 ) reagiert mit Dicarbonyl(cyclopentadienyl)(tetrahydrofuran)mangan ( 1a ) bzw. Dicarbonyl(methylcyclopentadienyl)(tetrahydrofuran)mangan ( 1b ) zu den Acetophenonimin‐Komplexen 5a ‐bzw. b , IR‐ und 1 H‐NMR‐spektroskopische Befunde machen die Koordination des Imin‐Liganden über das Stickstoff‐Atom an das Metall wahrscheinlich. 5a wurde anhand seines Fragmentierungsschemas auch massenspektroskopisch gesichert.
Residential Electrical Load Monitoring and Modeling – State of the Art and Future Trends for Smart Homes and Grids (2020)

Building energy consumption accounts for a large fraction of the total global energy usage, and considerable energy savings are expected to be achieved in this respect through residential electrical load monitoring. Due to the limitations on the practical implementation of in-depth and expensive monitoring systems, non-intrusive load monitoring (NILM) is becoming a hot topic. In this paper, an overview of the state of the art residential electrical load monitoring is presented. Different from previous reviews, the applications of load monitoring are particularly addressed, based on which, technical challenges of load monitoring techniques, including NILM, are identified and thoroughly discussed, together with possible developments and trends predicted from the authors’ perspective.
The enhancement of bearing fault detection using narrowband interference cancellation (2013)

Bearings play an important role in mechanical transmission. Many disasters are due to bearing faults. This has driven the need in research for early bearing fault detection. The goal is to extract the periodic impulse signals from the very noise signal which are indicative of a bearing fault. This is done by enhancing impulsive signals while suppressing other signals. This paper used a new method, Narrowband Interference Cancellation, to detect incipient bearing fault. This method filters the narrowband signal not associated with the impulsive signal produced by bearing fault. This improves the signal to noise ratio of impulse train associated with the bearing fault frequency. Finally this methodology is demonstrated on a bearing outer race fault.
Beyond Genomics: Detecting Codes and Signals in the Cellular Transcriptome (2006)

Summary form only given, as follows. Construction of the discrete genome sequence was the fi rst step in developing a comprehensive understanding of how cellular processes are controlled by bio-molecules and their interactions. That step is now mostly complete and the next step is to determine how DNA subsequences encode instructions for producing RNA transcripts and how continuous abundances of transcripts in cells combine to control activities. This is a much more challenging task than genome assembly, because the encoding of genetic instructions turns out to be far richer than was previously thought, and the detection and analysis of continuous cellular signals is more diffi cult than discrete symbol detection. Only preliminary progress has been made in assembling and analyzing the 'transcriptome' and the fi rst genome-wide data sets enabling the study of transcripts and their interactions have only recently been published. In this talk, I'll describe several open research problems in this area and discuss how they can be approached using representations and algorithms familiar to researchers in the information theory community.
The impact of address allocation and routing on the structure and implementation of routing tables (2003)

The recent growth in the size of the routing table has led to an interest in quantitatively understanding both the causes (eg multihoming) as well as the effects (eg impact on router lookup implementations) of such routing table growth. In this paper, we describe a new model called ARAM that defines the structure of routing tables of any given size. Unlike simpler empirical models that work backwards from effects (eg current prefix length distributions), ARAM approximately models the causes of table growth (allocation by registries, assignment by ISPs, multihoming and load balancing). We show that ARAM models with high fidelity three abstract measures (prefix distribution, prefix depth, and number of nodes in the tree) of the shape of the prefix tree --- as validated against 20 snapshots of backbone routing tables from 1997 to the present. We then use ARAM for evaluating the scalability of IP lookup schemes, and studying the effects of multihoming and load balancing on their scaling behavior. Our results indicate that algorithmic solutions based on multibit tries will provide more prefixes per chip than TCAMs (as table sizes scale toward a million) unless TCAMs can be engineered to use 8 transistors per cell. By contrast, many of today's SRAM-based TCAMs use 14-16 transistors per cell.