gebhart/patrepeval huggingface dataset:
The cultural effects of time usage and process complexity on control performance (2005)

Past research has classified people as monochrons (M) or polychrons (P) depending on their use of time. When people encounter many tasks, monochrons do one thing at a time while polychrons do many things at once. This study attempts to investigate how task difficulty and task priority influence the strategy and performance of monochrons and polychrons. A hill-climbing task was used to simulate a bivariate process control task. Participants were requested to find the optimum (hill-top) of two differing hills and remain at the top using the minimum number of clicks. The Modified Polychronic Attitude Index 3 scale (Lindquist et al., 2001) and Inventory of Polychronic Values scale (Bluedorn et al., 1999) were used to classify the participants as monochrons or polychrons. A fullfactorial within-subject experiment with 2 time-use groups, 4 task difficulties, 3 priorities, and 8 trials was conducted. The strategy and performance measures of each individual were calculated. Results showed that the strategies and performances were significantly different between monochrons and polychrons in the different task conditions. In general, the switching between the two tasks was less for monochrons compared to polychrons. Overall performance of polychrons was significantly better than that of monochrons. In addition, two and three-way interactions among the M/P group, difficulty and priority for both strategy and performance were significant. The results of this study may be used to determine the optimal performance of people having differing usages of time.
ChemInform Abstract: Lithiation of 2‐Me3SiCHRC5H4N (R = H or SiMe3): Influence of Solvent on the Nature of the Product (from X‐Ray Structure Determinations) and Asymmetric Induction. Lithiation of Some Analogous 3‐ and 4‐Methylpyridines. (1990)

Abstract Lithiation of the title compounds (III) and (IX) using LiBu (II) in hexane leads, depending on the conditions shown, to the different products (I) (space group P1, Z=2), (IV) ( P2 1 /n, Z=2), (VI) (P2 1 /c, Z=4), (VII) (P1, Z=1), (X) (Pbcn, Z=4), and (XII) (P2 1 2 1 2 1 , Z=4).
An Integrated CMOS RF Energy Harvester with Differential Microstrip Antenna and On-Chip Charger (2012)

This paper presents an energy harvesting system which extracts energy from radio frequency radiation for battery charging applications. It comprises of a new differential center tapped Micro strip antenna, off-chip matching circuit, on-chip novel CMOS rectifier and control circuitry in 180nm CMOS technology. For on-chip modules, thick oxide devices have been used so as to meet the charging requirements of the target batteries. The designed battery charging module charges either of 250 Ah and 10 Ah batteries according to the selected battery and available input power. The 250 Ah battery is charged at input power of 2dBm and 10 Ah battery is charged at input power of -6.5dBm. The fabricated antenna has a gain of 8.3dB and a VSWR less than 2 in the bandwidth from 844 to 970MHz. An efficient Periodic Steady State(PSS)-based power matching technique is also presented which improves the system efficiency. For 0dBm input power at 950 MHz to the antenna the proposed technique leads to 55.2% efficiency of RF to DC converter system. In addition to the integrated design a discrete rectifier using high frequency Schottky diodes and differential micro strip antenna at the input are fabricated. The discrete system uses the proposed matching technique and exhibits efficiency of 40% for-11dBm received power by the antenna.
Les grandes tendances de l’innovation biomédicale au XXIe siècle (2011)

Monsieur l’Administrateur, Mes Chers Collègues, Chers Amis, Mesdames, Messieurs, En premier lieu, je voudrais remercier Pierre Corvol et Philippe Kourilsky, ainsi que Mesdames et Messieurs les professeurs, de me donner l’opportunité de partager ma vision sur les grandes tendances qui, aujourd’hui, dessinent l’innovation médicale. Norman Augustine, l’ancien président de l’Académie nationale d’Engineering des États-Unis faisait remarquer que les institutions dédiées au savoir font preuve d’une ...
ChemInform Abstract: α‐Alkyl‐α‐aminosilanes: Synthesis via Alkylation and Hydrosilylation (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Primer containing dimethylaminododecyl methacrylate kills bacteria impregnated in human dentin blocks (2016)

Antibacterial dimethylaminododecyl methacrylate (DMADDM) was recently synthesized. The objectives of this study were to: (1) investigate antibacterial activity of DMADDM-containing primer on Streptococcus mutans impregnated into dentin blocks for the first time, and (2) compare the antibacterial efficacy of DMADDM with a previous quaternary ammonium dimethacrylate (QADM). Scotchbond Multi-Purpose (SBMP) bonding agent was used. DMADDM and QADM were mixed into SBMP primer. Six primers were tested: SBMP control primer P, P+2.5% DMADDM, P+5% DMADDM, P+7.5% DMADDM, P+10% DMADDM, and P+10% QADM. S. mutans were impregnated into human dentin blocks, and each primer was applied to dentin to test its ability to kill bacteria in dentinal tubules. Bacteria in dentin were collected via a sonication method, and the colony-forming units (CFU) and inhibition zones were measured. The bacterial inhibition zone of P+10% DMADDM was 10 times that of control primer (P<0.05). CFU in dentin with P+10% DMADDM was reduced by three orders of magnitude, compared with control. DMADDM had a much stronger antibacterial effect than QADM, and antibacterial efficacy increased with increasing DMADDM concentration. Dentin shear bond strengths were similar among all groups (P>0.1). In conclusion, antibacterial DMADDM-containing primer was validated to kill bacteria inside dentin blocks, possessing a much stronger antibacterial potency than the previous QADM. DMADDM-containing bonding agent was effective in eradicating bacteria in dentin, and its efficacy was directly proportional to DMADDM mass fraction. Therefore, DMADDM may be promising for use in bonding agents as well as in other restorative and preventive materials to inhibit bacteria.
Regulation of oxygen uptake in resting and pentagastrin-stimulated canine stomach (1982)

The relation between oxygen uptake and blood flow in the isolated dog stomach was investigated under resting conditions and during intra-arterial infusion of isoproterenol or pentagastrin. Blood flows above and below control values were achieved by pump perfusion and partial arterial occlusion, respectively. In the resting stomach oxygen uptake increased from 0.4 to 1.5 ml.min-1.100 g-1 as blood flow increased from 4 to 40 ml.min-1.100 g-1 and then remained constant for blood flows up to 100 ml.min-1.100 g-1. Isoproterenol did not significantly alter the relation between oxygen uptake and blood flow. In pentagastrin-stimulated stomachs oxygen uptake was maintained at 2.5 ml.min-1.100 g-1 at blood flows between 40 and 100 ml.min-1.100 g-1 and decreased at blood flows below 40 ml.min-1.100 g-1. The results indicate that pentagastrin increases oxidative metabolism in the stomach. Despite this increase in oxygen consumption with pentagastrin, the general shape of the relation between blood flow and oxygen uptake remained the same and was simply displaced vertically above the control data.
Robust microphone array using subband adaptive beamformer and spectral subtraction (2003)

This paper presents a new robust microphone array to enhance speech signal under the influence of noise and jammer(s). The proposed structure comprises of a soft constrained subband beamformer, a blocking system and a non-coherent processing technique. The soft constrained beamformer enhances the desired speech signal in a specified region by suppressing all side-lobes. This enhanced signal is then used as a reference signal by the blocking system to estimate the interference spectrum. Finally, the beamformer's output is spectral subtracted using the estimated interference spectrum. Simulations in a real office environment show higher interference suppression level compared to those obtained using the soft constrained beamformer only. Most importantly. this is achieved with negligible expense on target signal distortion.
STUDIES ON A NEW PIGMENT ANTIBIOTIC, CHROTHIOMYCIN (1969)

A new pigment antibiotic named chrothiomycin, which inhibits the growth of some Gram-positive bacteria and the enzymic activities of oxygenases involved in catecholamine biosynthesis in vitro, was isolated from fermentation broths of Streptomyces pluricolorescens. It is obtained as blackish purple crystals, C27H31-33O13NS.
As características dos professores de Educação Física que influenciam um estilo de vida ativo e saudável (2022)

As caraterísticas dos professores de Educação Física têm sido objeto de estudo como forma de explorar os conceitos de “bom professor” e de “professor eficaz”. De acordo com a National (2004), os professores de Educação Física devem ser a base de desenvolvimento dos alunos, no que diz respeito aos seus conhecimentos e habilidades, por forma a tornarem-se pessoas fisicamente ativas (<em>Association for Sport and Physical Education</em> [NASPE], 2004). O objetivo do estudo prende-se em verificar a influência das caraterísticas dos professores na promoção de estilos de vida ativos e saudáveis dos seus alunos após a escolaridade obrigatória. Foram entrevistados 26 indivíduos de forma casuística através de uma amostragem por conveniência dos 18 aos 30 anos, após escolaridade obrigatória sendo, posteriormente, realizada a transcrição e análise de conteúdo. A fidelidade intra e inter-observador foram analisadas através da fórmula de Bellack, com uma correspondência respetiva de 94% e 82%. Verificou-se que 38,5% dos inquiridos tiveram uma influência positiva na prática de estilos de vida ativos e saudáveis pelos seus professores após a escolaridade obrigatória e 61,5% revelaram que os professores de Educação Física não tiveram qualquer tipo de influência nos seus estilos de vida ativos e saudáveis. A motivação/incentivo, a relação professor-aluno e a exigência com os alunos foram as caraterísticas mais referenciadas pelos inquiridos.
Abstract A02: Photodynamic therapy in combination with immunotherapy enhances the long-term cure of bladder cancer in tumored mice (2020)

Abstract Introduction and Objectives: To investigate the utility of combination approach for treating bladder cancer, mice bearing UMUC3 (human transitional cell carcinoma) and T24 (human urinary bladder) tumors were treated with HPPH (2-[1-hexyloxyethyl]-2-devinyl pyropheophorbide-a)-PDT alone and in combination with BCG. The HPPH, a multifunctional agent, was selected as a photosensitizer because of its higher tumor avidity, improved fluorescence imaging ability, and limited skin phototoxicity than Photofrin, a current clinical standard. Methods: Imaging: IVIS/Spectrum: A noninvasive in vivo, continuous wave fluorescence imaging apparatus used to assess the localization and distribution of the PS at variable time points. In vivo efficacy studies using UMUC3 and T24 tumors in SCID mice with PS HPPH in combination with BCG. Results: Imaging: Tumor uptake in UMUC3 and T24 tumors using IVIS Imaging. PS HPPH showed high tumor uptake and significant difference in their pharmacokinetic profiles in UMUC3 and T24 tumors implanted in SCID mice: The SCID mice bearing either UMUC3 or T24 tumors (4-5 mm size) were injected with the PS HPPH. The tumored mice (3 mice/group) at a dose of 0.47 u-mol/kg) and imaged at variable time points. The uptake of tumor, liver, and skin was measured by IVIS system and interesting pharmacokinetic profiles of the PS were observed. The optimal tumors uptake in UMUC3 and T24 were at 24 hours and 8-12 hours, respectively. In vivo efficacy studies: PS (HPPH) in combination with BCG shows enhanced PDT efficacy CR (Cures) Day 30 = 14/22 = 63.6% and RG (Re-Growth) 6/22 = 36.4% in bladder tumors (UMUC3). To investigate the utility of combination treatment approach for treating bladder cancer, mice bearing UMUC3 tumors were injected intravenously with HPPH (0.47 u-mol/kg) and the tumors were exposed to laser light (135 J/cm2, 75 mW/cm2) at 24 h post-injection. One hour after the PDT treatment, BCG was injected (1-1.5 × 106 CFU), SQ weekly x 3 doses, and at day 30 the results are very encouraging. Conclusions: The HPPH showed higher in vivo uptake (determined by fluorescence) in UMUC3 and T24 bladder cancer tumors with significant differences in the two tumor types. The treatment of HPPH-PDT in combination with BCG using SCID mice bearing UMUC3 tumors showed enhanced long-term tumor cure. Before initiating this approach to human phase I clinical trial, further studies are under way. Source of funding: Roswell Park Alliance Foundation. Citation Format: Farukh Durrani, Ahmed Aly, Khurshid Guru, Ravindra Pandey. Photodynamic therapy in combination with immunotherapy enhances the long-term cure of bladder cancer in tumored mice [abstract]. In: Proceedings of the AACR Special Conference on Bladder Cancer: Transforming the Field; 2019 May 18-21; Denver, CO. Philadelphia (PA): AACR; Clin Cancer Res 2020;26(15_Suppl):Abstract nr A02.
Effet santé des phyto-oestrogènes (2001)

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THE SEPARATION AND ESTIMATION OF RIBOFLAVIN AND ITS DERIVATIVES IN MIXTURES (1962)

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Identification of Germacrene-D, One of the Volatile Metabolites produced by Actinomycetes (1980)

Ten strains of Actinomycetes producing, earthy-musty odor were isolated from the bottom sediment in Chidorigafuchi, the moat of the Imperial Palace. Their volatile metabolites were identified by gas chromatography-mass spectrometry. The Actinomycetes were cultured at 28°for 14 days on oatmeal agar and the cultured media were subjected to steam distillation to recover volatile metabolites. 2-Methylisoborneol and Geosmin were found in all cultured media, ranging from trace to 3000μg/254cm2. Newly identified Germacrene-D was found in all Actinomycetes, ranging from trace to 78μg/254cm2.
A reverse write assist circuit for SRAM dynamic write V<inf>MIN</inf> tracking using canary SRAMs (2014)

SRAMs occupy a large amount of area in modern system on chip circuits. With the growing trend of device scaling in deep sub-micron technologies, the 6T SRAM write operation is more vulnerable than the read operation from a failure standpoint. In order to make the SRAMs operate correctly, we must design them with some guard band above the minimum operating voltage (V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MIN</inf> ) by designing for the worst case. In this paper, we investigate a reverse write assist circuit scheme that enables the tracking of SRAM write V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MIN</inf> by using canary SRAM bitcells to track dynamic voltage, temperature fluctuations and aging effects. This circuit ultimately allows us to lower the write V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MIN</inf> below the worst case corner (SF_85C) V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MIN</inf> , which saves a minimum of 30.7% energy per cycle at the SS_85C, and a maximum of 51.5% energy per cycle at the FS_85C corner.
Metabolic network reconstruction of Chlamydomonas offers insight into light‐driven algal metabolism (2011)

Metabolic network reconstruction encompasses existing knowledge about an organism's metabolism and genome annotation, providing a platform for omics data analysis and phenotype prediction. The model alga Chlamydomonas reinhardtii is employed to study diverse biological processes from photosynthesis to phototaxis. Recent heightened interest in this species results from an international movement to develop algal biofuels. Integrating biological and optical data, we reconstructed a genome-scale metabolic network for this alga and devised a novel light-modeling approach that enables quantitative growth prediction for a given light source, resolving wavelength and photon flux. We experimentally verified transcripts accounted for in the network and physiologically validated model function through simulation and generation of new experimental growth data, providing high confidence in network contents and predictive applications. The network offers insight into algal metabolism and potential for genetic engineering and efficient light source design, a pioneering resource for studying light-driven metabolism and quantitative systems biology.
Regulation of Suppressor of Cytokine Signaling 3 (SOCS3) mRNA Stability by TNF-α Involves Activation of the MKK6/p38MAPK/MK2 Cascade (2007)

The potential of some proinflammatory mediators to inhibit gp130-dependent STAT3 activation by enhancing suppressor of cytokine signaling (SOCS) 3 expression represents an important molecular mechanism admitting the modulation of the cellular response toward gp130-mediated signals. Thus, it is necessary to understand the mechanisms involved in the regulation of SOCS3 expression by proinflammatory mediators. In this study, we investigate SOCS3 expression initiated by the proinflammatory cytokine TNF-alpha. In contrast to IL-6, TNF-alpha increases SOCS3 expression by stabilizing SOCS3 mRNA. Activation of the MAPK kinase 6 (MKK6)/p38(MAPK)-cascade is required for TNF-alpha-mediated stabilization of SOCS3 mRNA and results in enhanced SOCS3 protein expression. In fibroblasts or macrophages deficient for MAPK-activated protein kinase 2 (MK2), a downstream target of the MKK6/p38(MAPK) cascade, basal SOCS3-expression is strongly reduced and TNF-alpha-induced SOCS3-mRNA stabilization is impaired, indicating that MK2 is crucial for the control of SOCS3 expression by p38(MAPK)-dependent signals. As a target for SOCS3 mRNA stability-regulating signals, a region containing three copies of a pentameric AUUUA motif in close proximity to a U-rich region located between positions 2422 and 2541 of the 3' untranslated region of SOCS3 is identified. One factor that could target this region is the zinc finger protein tristetraprolin (TTP), which is shown to be capable of destabilizing SOCS3 mRNA via this region. However, data from TTP-deficient cells suggest that TTP does not play an irreplaceable role in the regulation of SOCS3 mRNA stability by TNF-alpha. In summary, these data indicate that TNF-alpha regulates SOCS3 expression on the level of mRNA stability via activation of the MKK6/p38(MAPK) cascade and that the activation of MK2, a downstream target of p38(MAPK), is important for the regulation of SOCS3 expression.
Rank Awareness in Joint Sparse Recovery (2010)

In this paper we revisit the sparse multiple measurement vector (MMV) problem where the aim is to recover a set of jointly sparse multichannel vectors from incomplete measurements. This problem has received increasing interest as an extension of the single channel sparse recovery problem which lies at the heart of the emerging field of compressed sensing. However the sparse approximation problem has origins which include links to the field of array signal processing where we find the inspiration for a new family of MMV algorithms based on the MUSIC algorithm. We highlight the role of the rank of the coefficient matrix X in determining the difficulty of the recovery problem. We derive the necessary and sufficient conditions for the uniqueness of the sparse MMV solution, which indicates that the larger the rank of X the less sparse X needs to be to ensure uniqueness. We also show that the larger the rank of X the less the computational effort required to solve the MMV problem through a combinatorial search. In the second part of the paper we consider practical suboptimal algorithms for solving the sparse MMV problem. We examine the rank awareness of popular algorithms such as SOMP and mixed norm minimization techniques and show them to be rank blind in terms of worst case analysis. We then consider a family of greedy algorithms that are rank aware. The simplest such algorithm is a discrete version of MUSIC and is guaranteed to recover the sparse vectors in the full rank MMV case under mild conditions. We extend this idea to develop a rank aware pursuit algorithm that naturally reduces to Order Recursive Matching Pursuit (ORMP) in the single measurement case and also provides guaranteed recovery in the full rank multi-measurement case. Numerical simulations demonstrate that the rank aware algorithms are significantly better than existing algorithms in dealing with multiple measurements.
Recognition by Class II Alloreactive T Cells of Processed Determinants from Human Serum Proteins (1991)

Alloreactive T cells recognize a complex composed of an allogeneic major histocompatibility complex (MHC) molecule and a peptide derived from the processing of nonpolymorphic proteins. A sizable fraction of MHC class II alloreactive T cells is shown to recognize peptides derived from constitutive processing of human serum proteins. One such epitope is a fragment of human serum albumin. This epitope bound selectively to the human class II molecule DRw11 and was constitutively present on antigen-presenting cells in vivo. These data indicate that, in the case of MHC class II, peptides involved in allorecognition may originate from exogenous proteins.
Biyopotansiyeller ve Ölçüm Cihazları (2012)

Many organs in the human body, produces many different types of the electric activity, such as the muscle groups, heart, brain and eyes. These electric activities are also called biopotentials. Measurement of the biopotentials from the human body can indicated vital clues as to normal or pathological functions of the organs. Biopotential signals are small in amplitude and consists of very low frequencies. Therefore, the signals need to be amplified and filtered to make them compatible with devices such as displays, recorders, or analog to digital converters for computerized equipment. In addition, biopotential measurements are corrupted by environmental and biological sources of interference. Amplifiers and filters adequate to measure these signals have to satisfy very specific requirements. This study reviews the origins, acuisition of biopotentials, and design of the medical instruments used in biopotential measurement.
Using statistical properties of short subsequences in microbial identification (2004)

We found specific contributions of different pathologies on MTL substructure in this population with AD neuropathology. The anterior hippocampus may be a relevant region to detect concomitant TDP-43 pathology in the MTL of patients with AD.
Complete repair of dystrophic skeletal muscle by mesoangioblasts with enhanced migration ability (2006)

The IL-1 micrograph in the original version of Fig. 1 B was a duplicate of the C2C12 0 days micrograph in Fig. 1 A. The authors have indicated that this was due to a clerical error during figure preparation.