gebhart/patrepeval huggingface dataset:
Numerical modeling of groundwater flow in the crystalline-rock aquifer in the vicinity of the Savage Municipal Water-Supply Well Superfund site, Milford, New Hampshire (2021)

First posted November 16, 2021 For additional information, contact: Director, New England Water Science CenterU.S. Geological Survey10 Bearfoot RoadNorthborough, MA 01532 In 2010, tetrachloroethylene (PCE), a chlorinated volatile organic compound, was detected in groundwater from deep (more than 300 feet below land surface) fractures in monitoring wells tapping a crystalline-rock aquifer. The aquifer underlies the Milford-Souhegan glacial-drift aquifer, a high water-producing aquifer, and the Savage Municipal Water-Supply Well Superfund site in Milford, New Hampshire. Between 30 and 40 residential water-supply wells are near (0.25 mile north of) the PCE-contaminated monitoring wells. Some of the residential water-supply wells are likely installed in similar rock types and formations as those of the monitoring wells installed as part of the Superfund site. As of 2020, periodic sampling by the U.S. Environmental Protection Agency and New Hampshire Department of Environmental Services (cooperative partners for this study) since 1996 had not detected PCE in groundwater from the residential water-supply wells. Nevertheless, understanding the vulnerability of the residential water wells to capture PCE contaminated groundwater was of concern.A numerical groundwater flow model was developed by the U.S. Geological Survey to assess groundwater flow and advective transport of PCE-contaminated groundwater in the crystalline-rock aquifer of the Milford area. The model (called the area-wide model) encompasses a 26.5-square mile area to allow for more accurate computation of water fluxes near the PCE-contaminated monitoring wells and the residential water wells. Simulations with the area-wide model show that, with the 2016 configuration of residential wells, capture of PCE by the residential water wells appears unlikely for hydrologic conditions typical of 2010 based on steady-state, advective transport modeling. However, simulations also show that adding residential water wells to the north of the PCE-contaminated monitoring wells could affect the transport of PCE. Groundwater withdrawals at other adjacent wells in the overlying Milford-Souhegan glacial-drift aquifer affect advective transport in the crystalline-rock aquifer. Therefore, the potential for future changes in withdrawals in the area, as well as changes in hydrologic conditions, including groundwater recharge and streamflow amounts, should be considered in the remedial assessment process. The development of the area-wide model and linkages established by this study with previously developed Milford-Souhegan glacial-drift aquifer transport models will help facilitate the development of remedial strategies for this Superfund site.
Preparation and Spectroscopic Properties of Phenanthrene-Labeled SEBS Triblock Copolymers (1999)

Phenanthrene-labeled poly(styrene-b-poly(ethylene-co-butylene)-b-polystyrene triblock copolymers (SEBS) have been prepared from a maleated derivative of the polymer. The dye was attached either through an imine or an ester linkage. The model compound 4, N-phenanthrylmethyl succinimide, exhibits an exponential fluorescence decay in deaerated THF solution, with a lifetime of τ0 = 44.5 ns. However, the fluorescence decays of the labeled SEBS polymers, both in film and in solution, could only be fitted with a sum of three exponential functions, with lifetimes approximately equal to 2, 14, and 44 ns. The long lifetime coincides with that of unquenched phenanthrene. The shortest lifetime, 2 ns, was attributed to polystyrene (PS) emission and could be corrected using the decay of the PS component of unlabeled SEBS (τPS ≈ 2 ns). The 14 ns lifetime appears to be a result of phenanthrene self-quenching brought about by local aggregation, driven not by the dye itself but by the functional group used to attach the dye to the polymer, the succinimide group or the −COOH groups of the succinate monoester derivative. Upon full methylation of the acid groups in the phenanthrylmethyl−ester-labeled SEBS copolymer, the interaction between the acid groups is removed and the extent of phenanthrene aggregation is strongly reduced. After correction for the PS emission, the phenanthrene decay profiles of the fully methylated SEBS copolymer, both in solution and in the film, could be fitted with only one exponential.
Cervicomedullary Region Spinal Artery Aneurysms: Report of Seven Cases with Review of Etiology and Management Strategies (2019)

Introduction: Spinal artery aneurysms in the cervicomedullary region are very rare, limited to single case reports in the literature. They can be associated with pathology that increases hemodynamic stress (such as AVMs or aortic coarctation), alter the blood vessel wall (infectious or inflammatory processes) or in isolation. They occur most commonly in the thoracic spine. When they are a cause of intracranial subarachnoid hemorrhage, their diagnosis is often missed as they are rarely encountered in clinical practice. We report our experience with a series of seven patients with this unique pathology.
ChemInform Abstract: SYNTHESIS OF 2‐ACYL AND 2‐HALOTHIETAN 1,1‐DIOXIDES (1975)

Abstract 2,2‐Dimethylthietan‐l ,l‐dioxid (I) wird durch Butyllithium in Tetrahydrofuran bei ‐70°C metalliert und anschließend mit einem Carbonsäureester (II) zum 2‐Acyl‐Derivat (III) umgesetzt.
Design, Testing and Kinetic Analysis of Bulky Monodentate Phosphorus Ligands in the Mizoroki–Heck Reaction (2012)

Abstract A series of new monodentate phosphane ligands 2 have been evaluated in the Mizoroki–Heck arylation reaction of iodobenzene and styrene and compared with our previously reported ligands, 1 , 3 and 4 . The concept of rational ligand design is discussed, and we describe how the performance of this new ligand family could be predicted. Employing our best ligand, 3,3′‐di‐ tert ‐butyl‐5,5′‐dimethoxybiphenyl‐2,2′‐diyl diisopropylphosphoramidite ( 3b ), we explored the scope of the reaction with regards to solvent and the substrate. We also investigated the electronic dependence of the reaction by analysing the relationship between the rate and Hammett constant. Sufficient steric bulk is required to enforce the catalytic reaction to proceed through the mono‐coordinated palladium species, thereby increasing its reactivity. The electronic properties determine the concentration of the active species from the monomer dimer equilibrium and their intrinsic reactivity. The cyclic phosphoramidite 3b provides an optimum in both properties within the systems studied, resulting in a rate limiting migratory insertion step.
Physical and optical properties of the International Simple Glass (2019)

Abstract Radioactive waste immobilization is a means to limit the release of radionuclides from various waste streams into the environment over a timescale of hundreds to many thousands of years. Incorporation of radionuclide-containing wastes into borosilicate glass during vitrification is one potential route to accomplish such immobilization. To facilitate comparisons and assessments of reproducibility across experiments and laboratories, a six-component borosilicate glass (Si, B, Na, Al, Ca, Zr) known as the International Simple Glass (ISG) was developed by international consensus as a compromise between simplicity and similarity to waste glasses. Focusing on a single glass composition with a multi-pronged approach utilizing state-of-the-art, multi-scale experimental and theoretical tools provides a common database that can be used to assess relative importance of mechanisms and models. Here we present physical property data (both published and previously unpublished) on a single batch of ISG, which was cast into individual ingots that were distributed to the collaborators. Properties from the atomic scale to the macroscale, including composition and elemental impurities, phase purity, density, thermal properties, mechanical properties, optical and vibrational properties, and the results of molecular dynamics simulations are presented. In addition, information on the surface composition and morphology after polishing is included. Although the existing literature on the alteration of ISG is not extensively reviewed here, the results of well-controlled static alteration experiments are presented here as a point of reference for other performance investigations.
Modeling of grain drying in continuous cross‐flow sliding bed dryers (1996)

Abstract Two mathematical models were developed in order to describe grain drying in continuous cross‐flow sliding bed dryers: a purely convective model and a diffusive model. It is shown both theoretically and experimentally that diffusion is not fundamental for the proper description of corn and soybean in these dryers at usual operation conditions, in spite of the widespread usage of diffusion‐like models. Particularly, the purely convective model may be easily implemented and used to optimize drying operation at plant site.
Correction to Polysaccharide-Based Conjugates for Biomedical Applications (2016)

ADVERTISEMENT RETURN TO ISSUEPREVCorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Polysaccharide-Based Conjugates for Biomedical ApplicationsArijit Basu, Konda Reddy Kunduru, Ester Abtew, and Abraham J. Domb*Cite this: Bioconjugate Chem. 2016, 27, 5, 1427–1428Publication Date (Web):May 6, 2016Publication History Published online6 May 2016Published inissue 18 May 2016https://pubs.acs.org/doi/10.1021/acs.bioconjchem.6b00197https://doi.org/10.1021/acs.bioconjchem.6b00197correctionACS PublicationsCopyright © 2016 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views829Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (1009 KB) Get e-AlertscloseSUBJECTS:Conjugate acid-base pairs Get e-Alerts
Modulation Scheme Optimization for a Dual Three-Phase Active Bridge (D3AB) PFC Rectifier Topology (2019)

The recently presented Dual Three-Phase Active Bridge (D3AB) converter integrates a three-phase Power Factor Corrected (PFC) rectifier and a DC-DC converter stage with galvanic isolation, originating from the Dual Active Bridge converter, in a single converter unit, and accordingly features low complexity, high efficiency, and high power density. This paper proposes a multi-objective optimization procedure that considers the objectives of low RMS transformer currents and/or switching losses in order to identify Pareto-optimal low-loss modulation schemes for the D3AB rectifier that meet given specifications, prevent power pulsation, and facilitate interleaved operation. From the obtained results, which are verified by means of detailed circuit simulations, an improved modulation scheme is selected, which, compared to conventional modulation, reduces the primary-side switching losses by 54% and the total converter losses by 11%. Due to the general nature of the presented method, the application to other three-phase rectifier/inverter topologies is directly feasible.
Useofmycobacterial peptides and recombinant proteins forthediagnosisof bovinetuberculosis inskintest-positive cattle (2011)

problems weretargeted, inparticular animals withskin tuberculosis, animals vaccinated against Johne's disease andanimals that were positive inthestandard purified protein derivative (PPD)-based IFN-y test. Thetwostudy groupsconsisted of74Mycobacterium bovis-culture positive animals and72uninfected animals, all ofwhichtested positive inthecaudal fold tuberculin skin testeight to28daysbefore theblood test. Theuseofcombinations ofESAT-6 andCFP10 antigens, either asrecombinant proteins orpeptides, detected similar percentages ofM bovis-infected animals asthePPD-based IFN-y test, butproduced significantly fewer false positive reactions. ThePPD-based IFN-y test was veryeffective indifferentiating animals vaccinated against Johne's disease that were skin-test positive fromthose withbovine tuberculosis, andtheuseofPPDorspecific mycobacterial antigens minimised thenumberoffalse positive reactions inanimals withskin tuberculosis.
Fast Parallel Unbiased Diffeomorphic Atlas Construction on Multi-Graphics Processing Units (2009)

Unbiased diffeomorphic atlas construction has proven to be a powerful technique for medical image analysis, particularly in brain imaging. The method operates on a large set of images, mapping them all into a common coordinate system, and creating an unbiased common template for studying intra-population variability and interpopulation differences. The technique has also proven effective in tissue and object segmentation via registration of anatomical labels. However, a major barrier to the use of this approach is its high computational cost. Especially with the increasing number of inputs and data size, it becomes impractical even with a fully optimized implementation on CPUs. Fortunately, the highly element-wise independence of the problem makes it well suited for parallel processing. This paper presents an efficient implementation of unbiased diffeomorphic atlas construction on the new parallel processing architecture based on Multi-Graphics Processing Units (Multi-GPUs). Our results show that the GPU implementation gives a substantial performance gain on the order of twenty to sixty times faster than a single CPU and provides an inexpensive alternative to large distributed-memory CPU clusters.
Foot-Healthcare Application Using Inertial Sensor: Estimating First Metatarsophalangeal Angle From Foot Motion During Walking (2021)

Our purpose was to demonstrate the possibility of providing foot-healthcare application by using an in-shoe motion sensor (IMS) through validating the feasibility of applying an IMS for measuring the first metatarsophalangeal angle (FMTPA), which is the most important parameter regarding the common foot problem hallux valgus. Methods: The IMS signals can represent foot motions when the mid-foot and hindfoot were modelled as a rigid body. FMTPAs can be estimated from the foot-motion signals measured using an IMS embedded beneath the foot arch near the calcaneus side using a machine-learning method. The foot-motion signals were collected from 50 participants with different FMTPAs. The true FMTPAs were assessed from digital photography. Correlation-based feature-selection processes (significance level <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${p} &lt; 0.05$ </tex-math></inline-formula> ) were used to search for the predictors from the foot-motion signals. Leave-one-subject-out cross-validation, root mean squared error, and intra-class coefficients were used for FMTPA-estimation model evaluation. Results: Eleven FMTPA-impacted gait-phase clusters, which were used to construct effective foot-motion predictors, were observed in all gait-cycle periods except terminal swing. The range of the foot motion in the sagittal and coronal planes significantly correlated with the FMTPA ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${p} &lt; 0.05$ </tex-math></inline-formula> ). Linear regression could be the best method for constructing an FMTPA estimation model with a root mean squared error and intra-class correlation coefficient of 4.2 degrees and 0.789, respectively. Conclusion: The results indicate the reliability of our FMTPA estimation model constructed from foot-motion signals and the possibility to providing foot-healthcare applications by using an IMS.
Genome-wide imputation study identifies novel HLA locus for pulmonary fibrosis and potential role for auto-immunity in fibrotic idiopathic interstitial pneumonia (2016)

We have identified a genome-wide significant association between the HLA region and fIIP. Two HLA alleles are associated with fIIP and affect expression of HLA genes in lung tissue, indicating that the potential genetic risk due to HLA alleles may involve gene regulation in addition to altered protein structure. These studies reveal the importance of the HLA region for risk of fIIP and a basis for the potential etiologic role of auto-immunity in fIIP.
Phase-Averaging Methods for the Natural Flowfield of a Fluidic Oscillator (2015)

The presented study examines various methods for phase averaging the naturally oscillating flowfield of a scaled-up fluidic oscillator. No external trigger is employed to control the oscillation of the flow. Mathematical and signal conditioning approaches for phase averaging the data are categorized and described. The results of these methods are evaluated for their accuracy in capturing the natural flowfield. The respective criteria are based on the minimum fluctuation in oscillation period length, the conservation of velocity amplitudes, and the number of snapshots per phase-averaging window. Although all methods produce reasonable qualitative results, only two methods are identified to provide the desired quantitative accuracy and suitability for the investigated flowfield. The first method is based on conditioning a time-resolved pressure signal from the feedback channels in the oscillator. An autocorrelation applied to the reference signal improves the period identification. The second method employs a mathematical approach by means of proper orthogonal decomposition. Because the conventional use of proper orthogonal decomposition reveals shortcomings in quantitative accuracy, it is modified by imposing an even distribution of snapshots per phase angle window. The results demonstrate the feasibility and improved accuracy of the modified proper orthogonal decomposition. Therefore, accurate phase averaging can be conducted without the need for a time-resolved reference signal.
DNA Electrotransfer: An Effective Tool for Gene Therapy (2013)

Originally developed for monogenic diseases, and therefore associated with the compensa‐ tion of genes whose alteration is responsible for diseases, the concept of gene therapy has rapidly expanded to the use of DNA as a new type of drug. Therefore, gene therapy leads to indications which are far beyond the case of genetic diseases, since a DNA drug can, in prin‐ ciple, replace any medication which will control protein synthesis. Gene therapy seems an alternative choice to fight against diseases currently treated imperfectly, or not treated with conventional pharmaceutical approaches.
The Synthesis of Protein by Mammalian RNA Viruses (1971)

This chapter contains section titled: Poliovirus Vesicular Stomatitis Virus Conclusion References
Deep lithography with protons as an alternative fabrication technology for high-precision 2D fiber connector components (2004)

We present Deep Lithography with Protons (DLP) for the fabrication of ultra-dense fiber coupling elements which consist of circular, conical-shaped alignment features, ordered in a 2D array with high-precision pitches. This technology relies on the irradiation of PMMA-resist layers with a swift proton beam featuring a well-defined circular shape, followed by a selective development of these exposed zones. To increase the coupling efficiency, the DLP-technology allows to integrate uniform spherical micro-lenses, which are created by a controlled swelling of the proton-bombarded domains in a monomer vapor, in front of the micro-alignment holes. We will first discuss our work on the improvement of the DLP irradiation and development process step to enhance the coupling efficiency and the field-installability of the connector components. Furthermore, we will illustrate the optical design of micro-lens arrays and their integration in fiber connectors with improved tolerances.
Study on the mitigation of the resonance due to the power-bus structure using periodic metal-strip loaded sheets (2008)

This paper investigates a method to tackle the resonance problems of the rectangular power-bus structure(PBS) using thin sheets loaded with periodic metal strips. The equivalent surface impedance of the proposed loading is calculated and involved in the expression of the impedance that accounts for in the PBS, in order to improve the resonance behavior of the original structure. The effects of the strips and the immediate surroundings are illustrated by a number of numerical experiments. Also the restrictions of the technique are addressed.
Continuous Security Testing: A Case Study on Integrating Dynamic Security Testing Tools in CI/CD Pipelines (2020)

Continuous Integration (CI) and Continuous Delivery (CD) have become a well-known practice in DevOps to ensure fast delivery of new features. This is achieved by automatically testing and releasing new software versions, e.g. multiple times per day. However, classical security management techniques cannot keep up with this quick Software Development Life Cycle (SDLC). Nonetheless, guaranteeing high security quality of software systems has become increasingly important. The new trend of DevSecOps aims to integrate security techniques into existing DevOps practices. Especially, the automation of security testing is an important area of research in this trend. Although plenty of literature discusses security testing and CI/CD practices, only a few deal with both topics together. Additionally, most of the existing works cover only static code analysis and neglect dynamic testing methods. In this paper, we present an approach to integrate three automated dynamic testing techniques into a CI/CD pipeline and provide an empirical analysis of the introduced overhead. We then go on to identify unique research/technology challenges the DevSecOps communities will face and propose preliminary solutions to these challenges. Our findings will enable informed decisions when employing DevSecOps practices in agile enterprise applications engineering processes and enterprise security.
Radiation and Self Heating Effects in Hetero-Junction Bipolar Transistors (FY2019 L2 MileStone 6723 Report) (2019)

Hetero-Junction Bipolar Transistors (HBT) have several advantages over Silicon Bipolar Junction Transistors (BJT) in radiation environments. One advantage is an intrinsic hardness to displacement damage causing radiation. The generally smaller size of HBTs compared to BJTs also means that less photocurrent is generated by these devices. A disadvantage of the smaller size is less ability to dissipate heat due to smaller surface areas and contacts. This report describes simulations intended to study the initial heating of HBT transistors due to ionizing radiation events and the subsequent heating caused by feedback in the devices when responding to these events.
ChemInform Abstract: A Simple Method for Chelation Controlled Additions to α‐Amino Aldehydes. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.