gebhart/patrepeval huggingface dataset:
Evidence of Qi-gong Energy and its Biological Effect on the Enhancement of the Phagocytic Activity of Human Polymorphonuclear Leukocytes (2001)

In order to test for an effect of phosphate buffered saline (PBS) treated externally with Qi energy ("Qi-treated" PBS) on the phagocytic activity of human polymorphonuclear leukocytes (PMNs), rigorously controlled experiments employing masking and randomized procedures were carried out under independent monitoring. In all experiments, Qi treatment was externally applied under monitoring to newly purchased unopened 100 ml bottles of PBS, and the PMN phagocytic activity was sayed by one experimenter in masked, randomized and monitored conditions using a highly sensitive chemiluminescence method. Phagocytic activity data were obtained in triplicate for each sample and then statistically analyzed. The PBS samples Qi-treated by the Qi-gong master and by one of the Qi-gong trainees showed clear stimulation of PMN phagocytic activity which was significant statistically, and this phenomenon was highly reproducible. Out of 10 experiments by the Qi-gong master, only twice did Qi-treatment fail to influence the PBS. The activity of Qi-treated PBS decayed over days or weeks. Furthermore, it was found the Qi-treated PBS had decreased phagocytic stimulatory activity after microware treatment, but not after autoclave treatment. We also demonstrated that microwae irradiation and infrared laser pulse irradiation have similar effects on PBS as Qi- treatment. The results obtained in this experiment provide evidence of the existence of Qi energy, its ability to influence an electrolyte solution and its biological effect. Furthermore, microwave or infrared laser pulse treatment was found to partly mimic the Qi-treatment of PBS.
Dimethyl Acetylsuccinate as a Versatile Synthon in Heterocyclic Chemistry — A Facile Synthesis of Heterocyclic Acetic Acid Derivatives (2000)

The preparation of novel acetic acid derivatives of pyrazole 3a,b and pyrimidine 2a—e is achieved by condensation of dimethyl acetylsuccinate (1) with appropriate reaction partners. Also triethyl 1,1,2-ethanetricarboxylate (6) is a valuable starting material, which is demonstrated by the synthesis of previously unknown pyrimidin-5-yl acetates.
Partially Catalyzed Deuterium And Tritium-Assisted Plasma Characteristics (1982)

Partially catalyzed deuterium (PCD) fuel cycles and their sensitivity to ash buildup, radiation losses, Ti/Te. and 3He consumed are investigated. The study is machine independent, using a simple zero-dimensional steady-state model. The PCD fuel cycles include semi-catalyzed-deuterium where only a fraction of the 3He fuses and tritium-catalyzed-deuterium where 3He extracted from the plasma is converted into tritium, which is reinjected. Also considered is tritium-assisted operation where a fraction of the fusion neutrons is used to produce tritium, which is added to the PCD plasma.The PCD and tritium-assisted operation is shown to be attractive for certain nonelectrical applications. They avoid 3He recirculation required for catalyzed-deuterium (Cat-D) operation and enable simplified blanket designs. The ignition temperature, neт, and power density of PCD plasmas are very energy-balance sensitive, but under certain conditions these properties can be comparable or superior to those of Cat-D. Cyclotron radiation losses can significantly impair, whereas tritium assistance can strongly improve, PCD performance.
Fabrication of AlGaN/GaN heterostructures on halide vapor phase epitaxy AlN/SiC templates for high electron mobility transistor application (2023)

Abstract GaN films were grown on hydride vapor phase epitaxy (HVPE) AlN/SiC templates by metalorganic CVD (MOCVD) without annealing the reactor to eliminate the memory effect. A step-terrace structure and smooth surface were obtained for the GaN film, which had a thickness of ∼200 nm. Subsequently, AlGaN/GaN heterostructures for application in high electron mobility transistors (HEMTs) with thin GaN channels were fabricated without a C- or Fe-doped GaN buffer layer. The interface quality at the AlGaN/GaN heterostructure was good enough for a two-dimensional electron gas to exhibit Shubnikov–de Haas oscillation in a magnetic field at 1.8 K. The GaN HEMTs with a thin channel on the AlN/SiC templates exhibited both a pinch-off character and conventional properties. In view of both the shorter epitaxial growth time and higher thermal conduction, HVPE AlN/SiC templates are applicable to the fabrication of GaN HEMTs by MOCVD.
THE COMPARISON OF GPA REGRESSION EQUATIONS FOR REGULARLY ADMITTED AND DISADVANTAGED FRESHMEN AT THE UNIVERSITY OF ILLINOIS (1970)

The regression equations of first semester grade point average (GPA) on high school percentile rank (HSPR) and verbal and quantitative score on the Cooperative School and College Ability Tests (SCAT) were significantly different for men and women regularly admitted freshmen and men and women freshmen admitted to the Special Educational Opportunities Program (SEOP) at the University of Illinois. HSPR and SCAT verbal scores were useful predictors of GPA for all groups. However, separate regression equations for the prediction of GPA were indicated, since there were significant differences in the regression coefficients of all of the independent variables among the four groups.
Single-Fed Dual-Band Metal Grid Artificial Dielectric Antenna for Millimeter Wave Applications (2021)

A dual-band artificial metal grid dielectric resonator antenna (GDRA) operating at millimeter wave frequencies is presented. The embedded metal grids increase the effective permittivity of base dielectric composed of poly-methyl methacrylate (PMMA) and their I-shape allows for two unique modes. Simulation results demonstrate that the GDRA resonates at 28 and 38 GHz with 6.96 and 6.99 dBi gains, respectively. The GDRA can be tuned to operate as a lower single band, upper single band or as a dual-band antenna by adjusting the feed line dimension.
Time Resolved Spectroscopy of Some Aromatic N-Oxide Triplets, Radical Anions, and Related Radicals (2004)

Laser flash photolysis (LFP) and time-resolved infrared spectroscopy (TRIR) techniques and density function theory (DFT) calculations were used to investigate the electron-transfer chemistry of the triplet excited states of isoquinoline N-oxide (1), benzocinnoline N-oxide (2), and 4-nitroquinoline N-oxide (3). It was found that neither triplet 1 nor triplet 2 undergoes electron-transfer reactions with typical donors. Rather, they undergo net hydrogen atom transfer (proton-coupled electron transfer) with hydroquinone. Triplet 4-nitroquinoline N-oxide readily undergoes electron-transfer reactions as previously reported, to form the analogous radical anion and hydroradical. The structures of these species were identified by LFP and TRIR techniques with the aid of DFT calculations. The oxygen atom on the N-oxide group was found to be the protonation site of the radical anion of 3.
Synthesis of Homo- and Hetero-Bimetallic Complexes Containing the Ni(C6F5)2 Moiety – Crystal Structure of [(C6F5)2Ni(μ-SPh)2Pd(dppe)] (1998)

The compound cis-[Ni(C6F5)2(PhCN)2] has been used as the starting material for the preparation of the bimetallic complexes [(C6F5)2Ni(μ-X)2Ni(C6F5)2]2– (X = SCN, OCN, N3), [(C6F5)2Ni(μ-SCN)2Pd(C6F5)2]2–, [(C6F5)2Ni(μ-NCS)2Pd-(dppe)] [dppe = 1,2-bis(diphenylphosphanyl)ethane], and the trimetallic[(C6F5)2Ni(μ-NCS)2Pd(μ-SCN)2Ni(C6F5)2]2–. The mononuclear compounds [(C6F5)2NiLX] (L = PPh3, P(C6H4MeO-p)3; X = SCN, OCN) are obtained by reaction between [(C6F5)2Ni(&μ-X)2Ni-(C6F5)2]2– and L. The treatment of cis-[Ni(C6F5)2(PhCN)2] with [M(SAr)2(dppe)] leads to the formation of the arylthiolate complexes [(C6F5)2Ni(μ-SAr)2M(dppe)] (Ar = Ph, C6H4Me-p, C6H4NO2-p; M = Ni, Pd, Pt). The X-ray diffraction study of [(C6F5)2Ni(μ-SPh)2Pd(dppe)] shows that both metal atoms, Ni and Pd, are coordinated in a slightly distorted square-planar geometry and the μ-thiolato groups are in the syn conformation.
Millimeter Wave and Sub-THz Indoor Radio Propagation Channel Measurements, Models, and Comparisons in an Office Environment (2021)

This letter provides a comparison of indoor radio propagation measurements and corresponding channel statistics at 28, 73, and 140 GHz, based on extensive measurements from 2014–2020 in an indoor office environment. Side-by-side comparisons of propagation characteristics (e.g., large-scale path loss and multipath time dispersion) across a wide range of frequencies from the low millimeter wave band of 28 GHz to the sub-THz band of 140 GHz illustrate the key similarities and differences in indoor wireless channels. The measurements and models show remarkably similar path loss exponents over frequencies in both line-of-sight (LOS) and non-LOS (NLOS) scenarios, when using a one meter free space reference distance, while the multipath time dispersion becomes smaller at higher frequencies. The 3GPP indoor channel model overestimates the large-scale path loss and has unrealistic large numbers of clusters and multipath components per cluster compared to the measured channel statistics in this letter.
Modeling and Reduction of Radiated EMI due to Ground Impedance in a High-density Active-clamp Flyback Power Adapter (2022)

The article firstly reviewed the modeling and prediction techniques for radiated electromagnetic interference (EMI) in active-clamp Flyback (ACF) power adapters. Second, developed an improved radiated EMI model of the ACF power adapter based on circuit topologies, PCB parasitics, working voltage waveforms, antenna/converter impedance, and transfer functions. Third, the improved radiated EMI model was quantified and experimentally verified. Fourth, proposed two techniques for radiated EMI mitigation based on the improved radiated EMI model: optimizing PCB layout and adding a cross capacitor for resonance. Experiments verified the analysis and techniques. The techniques were also extended to other isolated power converter topologies.
Character of Organic Matter in Soil-Aquifer Treatment Systems (2006)

The objective of this study was to investigate the character and fate of bulk organics in reclaimed water used for groundwater recharge via soil-aquifer treatment (SAT). The study design followed a watershed guided approach considering hydraulically corresponding samples of drinking water sources, SAT-applied wastewater effluents, and subsequent post-SAT samples representing a series of different travel times in the subsurface. Water samples were fractionated into hydrophobic acids, transphilic acids, and hydrophilic carbon using a XAD resin-based protocol. Extensive characterization of organic carbon in the different samples was performed using state-of-the-art analytical techniques including excitation–emission matrix fluorescence spectroscopy, size exclusion chromatography, carbon-13 nuclear magnetic resonance spectroscopy (C-NMR13) , Fourier transform infrared spectroscopy (FTIR), and elemental analysis. During SAT, transphilic and hydrophilic organic matter were preferentially removed. The results generally demonstrated that naturally derived (NOM) and effluent-derived organic matter after SAT overlap extensively in molecular weight distribution, amount and distribution of hydrophobic and hydrophilic carbon fractions, and chemical characteristics based on elemental analysis and C-NMR13 and FTIR spectroscopy. However, the residual portion of the dissolved organic carbon contained both effluent-derived organic matter and NOM.
Mitomycin C-induced cell cycle arrest enhances 5-aminolevulinic acid-based photodynamic therapy for bladder cancer (2020)

This study demonstrated a new approach to enhance the effects of ALA-PDT using drugs that induce a dormancy-like status and upregulate porphyrin metabolism.
Organizational Issues in Establishing Geriatrics Interdisciplinary Team Training (2004)

The John A. Hartford Foundation-supported geriatrics interdisciplinary team training (GITT) initiative was a bold attempt to create a new educational agenda for the health professions. Although some components of GITT were previously in place at the eight institutions that participated in the Hartford initiative and at other institutions (e.g., Department of Veterans Affairs), never before has geriatrics interdisciplinary team training been so systematically planned, implemented, or evaluated. This paper focuses on four organizational factors essential to the establishment of a geriatrics interdisciplinary team training program: (1) organizational readiness to implement GITT, including the needs and existing resources of the organization; (2) partnerships, specifically the relationships between academic and clinical organizations; (3) institutional support, the tangible and intangible sources of support necessary at multiple levels within the organization; and (4) structure, the administrative and organizational requirements for team training programs. An analysis of these four factors and the influences upon them can help facilitate the successful implementation of interdisciplinary training programs at institutions considering this educational approach.
HIV-1 Vpr Enhances Viral Burden by Facilitating Infection of Tissue Macrophages but Not Nondividing CD4+ T Cells (2001)

Prior experiments in explants of human lymphoid tissue have demonstrated that human immunodeficiency virus type 1 (HIV-1) productively infects diverse cellular targets including T cells and tissue macrophages. We sought to determine the specific contribution of macrophages and T cells to the overall viral burden within lymphoid tissue. To block infection of macrophages selectively while preserving infection of T cells, we used viruses deficient for viral protein R (Vpr) that exhibit profound replication defects in nondividing cells in vitro. We inoculated tonsil histocultures with matched pairs of congenic viruses that differed only by the presence of a wild-type or truncated vpr gene. Although these viruses exhibited no reduction in the infection or depletion of T cells, the ability of the Vpr-deficient R5 virus to infect tissue macrophages was severely impaired compared with matched wild-type R5 virus. Interestingly, the Vpr-deficient R5 virus also exhibited a 50% reduction in overall virus replication compared with its wild-type counterpart despite the fact that macrophages represent a small fraction of the potential targets of HIV-1 infection in these tissues. Collectively, these data highlight the importance of tissue macrophages in local viral burden and further implicate roles for CC chemokine receptor 5, macrophages, and Vpr in the life cycle and pathogenesis of HIV-1.
Instantaneous frequency measurement correlators using optical approach (1992)

Preliminary results of a study aimed at the development of a simultaneous signal instantaneous frequency measurement (IFM) receiver using optical implementation methods are reported. A method for detecting simultaneous signals in an IFM receiver is briefly reviewed. Two architectures (coherent and incoherent) for optical phase correlators are then described and compared. Some considerations concerning the practical implementation of the two architectures are discussed.
Supplementary Table S4 from First-in-Human Study of the Radioligand <sup>68</sup>Ga-N188 Targeting Nectin-4 for PET/CT Imaging of Advanced Urothelial Carcinoma (2023)

&lt;p&gt;68Ga-N188 normal-organ absorbed doses in male (μGy/MBq, mean ± SD).&lt;/p&gt;
Investigation on Tethered Anion Effects in Solid Polymer Electrolytes for Li-Ion Batteries (2022)

Solid polymer electrolytes (SPEs) have been proposed to reduce concentration polarizations within batteries by immobilizing anions to the polymer matrix, which can help stabilize the electrodeposition process and extend Li-ion battery lifetime. Unfortunately, single-ion conducting SPEs continue to suffer from poor conductivity due to coupling with the slow segmental mobility of polymer chains and poor ion pair dissociation. Our group systematically investigated how different tethered anions affect the Li-ion conduction and polymer segmental mobility. Copolymers were synthesized using a common neutral monomer, poly(ethylene glycol) methyl ether methacrylate (PEGMA), with a series of different anionic monomers: 4-styrene sulfonate, 4-styrene phosphonate, 4-styrene TFSI, and methacrylate TFSI. These monomers presented a series of anions of varying strength with the same styrene structure, sulfonate vs. phosphonate vs. TFSI, as well as exploring structural monomer changes for the same TFSI anion, styrene vs. methacrylate, that allows for systematic changing of polymer electrolyte properties. Each copolymer series was further expanded by changing the composition of neutral-to-anionic monomers, ranging from 10-67 mol% anionic. The increased ion exchange capacity of the phosphonate groups led to a high degree of ion aggregation that exhibited hard mechanical properties and very low Li-ion conductivities. Increasing the electron delocalization of the ions from sulfonate to TFSI greatly improved the conductivities and lowered activation energies of ion transport, with methacrylate being slightly better than styrene. Implications of these results will be discussed for next-generation polymer electrolyte design.
Combined injection of three different lineages of early‐differentiating human amniotic fluid‐derived cells restores urethral sphincter function in urinary incontinence (2014)

Our novel concept of triple-combined early-differentiated cell therapy for the damaged sphincter may provide a viable option for incontinence treatment.
Extending LLVM IR for DPC++ Matrix Support: A Case Study with Intel® Advanced Matrix Extensions (Intel® AMX) (2021)

In this paper, we introduce a DPC++ matrix extension to unify different tensor hardware: Intel <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> Advanced Matrix Extensions (Intel <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> AMX) to CPUs, NVIDIA <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> TPUs, IBM <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> POWER <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">®</sup> MMA, etc. These tensor hardware units are usually accessed by low-level intrinsics or assembly to perform matrix operations. It is hard for scientists to program these domain- specific devices without the kind of high-level abstractions and efficient implementations we introduce here.We also extend the existing LLVM matrix intrinsics to represent this DPC++ extension and yield efficient Intel AMX code generation. Based on our case study of implementing this interface on Intel AMX hardware, we discuss some of the limitations of existing LLVM Intermediate Representation (IR) and how they can be overcome to exploit tensor hardware.
A stereoselective and preparative entry to 1,2-anhydrosugars through oxidation of glycals with perfluoro-cis-2,3-dialkyloxaziridines (1995)

Perfluoro-cis-2,3-dialkyloxaziridines 1 perform the direct epoxidation of glycals 2 to give cleanly corresponding 1,2-anhydrosugars 3 with medium to complete diastereoselection; elaboration of these glycals to glycosyl fluorides and lipid conjugates is also reported.
Integrative functional genomics identifies RINT1 as a novel GBM oncogene (2012)

Large-scale cancer genomics efforts are identifying hundreds of somatic genomic alterations in glioblastoma (GBM). Distinguishing between active driver and neutral passenger alterations requires functional assessment of each gene; therefore, integrating biological weight of evidence with statistical significance for each genomic alteration will enable better prioritization for downstream studies. Here, we demonstrate the feasibility and potential of in vitro functional genomic screens to rapidly and systematically prioritize high-probability candidate genes for in vivo validation. Integration of low-complexity gain- and loss-of-function screens designed on the basis of genomic data identified 6 candidate GBM oncogenes, and RINT1 was validated as a novel GBM oncogene based on its ability to confer tumorigenicity to primary nontransformed murine astrocytes in vivo. Cancer genomics-guided low-complexity genomic screens can quickly provide a functional filter to prioritize high-value targets for further downstream mechanistic and translational studies.
Aspergillus fumigatus Generates an Enhanced Th2-Biased Immune Response in Mice with Defective Cystic Fibrosis Transmembrane Conductance Regulator (2006)

Cystic fibrosis (CF) lung disease is characterized by persistent airway inflammation and airway infection that ultimately leads to respiratory failure. Aspergillus sp. are present in the airways of 20-40% of CF patients and are of unclear clinical significance. In this study, we demonstrate that CF transmembrane conductance regulator (CFTR)-deficient (CFTR knockout, Cftr(tm1Unc-)TgN(fatty acid-binding protein)CFTR) and mutant (DeltaF508) mice develop profound lung inflammation in response to Aspergillus fumigatus hyphal Ag exposure. CFTR-deficient mice also develop an enhanced Th2 inflammatory response to A. fumigatus, characterized by elevated IL-4 in the lung and IgE and IgG1 in serum. In contrast, CFTR deficiency does not promote a Th1 immune response. Furthermore, we demonstrate that CD4+ T cells from naive CFTR-deficient mice produce higher levels of IL-4 in response to TCR ligation than wild-type CD4+ T cells. The Th2 bias of CD4+ T cells in the absence of functional CFTR correlates with elevated nuclear levels of NFAT. Thus, CFTR is important to maintain the Th1/Th2 balance in CD4+ T cells.
Hybrid magneto photonic material structure for plasmon assisted magnetic switching (2020)

We have proposed the use of surface plasmon resonances at the interface of hybrid magneto-photonic heterostructures [ Opt. Mat. Express , 7 , 4316 ( 2017 ) 10.1364/OME.7.004316 ] for all-optical control of the macroscopic spin orientation in nanostructures in fs time scales. This requires strong spin-photon coupling for the resonant enhancement of opto-magnetic fields, generated through the inverse Faraday effect, in magnetic nanostructures with perpendicular anisotropy. Here we report on the development of nm thick interlayers to control the growth orientation of hcp-Co alloys grown on refractory plasmonic materials to align the magnetic axis out-of-plane, thereby meeting key requirements for the realization of ultrafast magneto-photonic devices.
Broadly neutralizing antibodies target a haemagglutinin anchor epitope (2021)

Broadly neutralizing antibodies that target epitopes of haemagglutinin on the influenza virus have the potential to provide near universal protection against influenza virus infection<sup>1</sup>. However, viral mutants that escape broadly neutralizing antibodies have been reported<sup>2,3</sup>. The identification of broadly neutralizing antibody classes that can neutralize viral escape mutants is critical for universal influenza virus vaccine design. Here we report a distinct class of broadly neutralizing antibodies that target a discrete membrane-proximal anchor epitope of the haemagglutinin stalk domain. Anchor epitope-targeting antibodies are broadly neutralizing across H1 viruses and can cross-react with H2 and H5 viruses that are a pandemic threat. Antibodies that target this anchor epitope utilize a highly restricted repertoire, which encodes two public binding motifs that make extensive contacts with conserved residues in the fusion peptide. Moreover, anchor epitope-targeting B cells are common in the human memory B cell repertoire and were recalled in humans by an oil-in-water adjuvanted chimeric haemagglutinin vaccine<sup>4,5</sup>, which is a potential universal influenza virus vaccine. To maximize protection against seasonal and pandemic influenza viruses, vaccines should aim to boost this previously untapped source of broadly neutralizing antibodies that are widespread in the human memory B cell pool.