gebhart/patrepeval huggingface dataset:
Ultrastable Optical Clock with Neutral Atoms in an Engineered Light Shift Trap (2003)

An ultrastable optical clock based on neutral atoms trapped in an optical lattice is proposed. Complete control over the light shift is achieved by employing the $5s^2 {}^1S_0 \to 5s5p {}^3P_0$ transition of ${}^{87}{\rm Sr}$ atoms as a "clock transition". Calculations of ac multipole polarizabilities and dipole hyperpolarizabilities for the clock transition indicate that the contribution of the higher-order light shifts can be reduced to less than 1 mHz, allowing for a projected accuracy of better than $ 10^{-17}$.
REACTEUR THERMOCHIMIQUE POUR STOCKAGE THERMIQUE : ANALYSE DU FONCTIONNEMENT LOCAL (2014)

International audience
Reply to “Funding by Lottery: Political Problems and Research Opportunities” (2016)

We thank Dr. Barnett for his kind comments (1). We agree that a major barrier to instituting a modified lottery is …
Thiol-promoted catalytic synthesis of diphenolic acid with sulfonated hyperbranched poly(arylene oxindole)s (2012)

Acid-catalyzed condensation of levulinic acid and phenol into high yields of diphenolic acid (>50%) is possible with a combination of sulfonated hyperbranched polymers and thiol promotors, either added as a physical mixture or bound to the polymer by ion-pairing.
Bandit-Based Power Control in Full-Duplex Cooperative Relay Networks (2021)

Full-duplex relaying is an enabling technique of sixth generation (6G) mobile networks, promising tremendous rate and spectral efficiency gains. In order to improve the performance of full-duplex communications, power control is a viable way of avoiding excessive loop interference at the relay. Unfortunately, power control requires channel state information of both source-relay and relay-destination channels, as well as of the loop interference channel, thus resulting in increased overheads. Aiming to offer a low-complexity alternative for power control in full-duplex relay networks, we adopt reward-based learning in the sense of multi-armed bandits. More specifically, we provide bandit-based power control algorithms, relying on acknowledgements/negative-acknowledgements observations by the relay. The proposed algorithms avoid the need for channel state information acquisition and exchange, and can be employed in a distributed manner. Performance evaluation results in terms of outage probability, average throughput and accumulated regret over time highlight an interesting performance-complexity trade-off compared to optimal power control with full channel knowledge and significant performance gains over the cases without power control and random power level selection.
High Expression of FGD3, a Putative Regulator of Cell Morphology and Motility, Is Prognostic of Favorable Outcome in Multiple Cancers (2017)

<i>FGD3</i> was previously shown to inhibit cell migration. FGD3 mRNA is regulated by <i>ESR1</i> and is associated with favorable outcome in six distinct breast cancer cohorts and four TCGA cancer cohorts. This suggests that FGD3 is an important clinical biomarker.
Optical trapping of a spherically symmetric sphere in the ray-optics regime: a model for optical tweezers upon cells (2006)

Since their invention in 1986, optical tweezers have become a popular manipulation and force measurement tool in cellular and molecular biology. However, until recently there has not been a sophisticated model for optical tweezers on trapping cells in the ray-optics regime. We present a model for optical tweezers to calculate the optical force upon a spherically symmetric multilayer sphere representing a common biological cell. A numerical simulation of this model shows that not only is the magnitude of the optical force upon a Chinese hamster ovary cell significantly three times smaller than that upon a polystyrene bead of the same size, but the distribution of the optical force upon a cell is also much different from that upon a uniform particle, and there is a 30% difference in the optical trapping stiffness of these two cases. Furthermore, under a small variant condition for the refractive indices of any adjacent layers of the sphere, this model provides a simple approximation to calculate the optical force and the stiffness of an optical tweezers system.
Induction of Cell Membrane Protrusions by the N-terminal Glutaredoxin Domain of a Rare Splice Variant of Human Thioredoxin Reductase 1 (2007)

The human thioredoxin system has a wide range of functions in cells including regulation of cell proliferation and differentiation, immune system modulation, antioxidant defense, redox control of transcription factor activity, and promotion of cancer development. A key component of this enzymatic system is the selenoprotein thioredoxin reductase 1 (TrxR1), encoded by the TXNRD1 gene. Transcription of TXNRD1 involves alternative splicing, leading to a number of transcripts also encoding isoforms of TrxR1 that differ from each other at their N-terminal domains. Here we have studied the TXNRD1_v3 isoform containing an atypical N-terminal glutaredoxin (Grx) domain. Expression of the transcript of this isoform was found predominantly in testis but was also detected in ovary, spleen, heart, liver, kidney, and pancreas. By immunohistochemical analysis in human testis with antibodies specific for the Grx domain of TXNRD1_v3, the protein was found to be predominantly expressed in the Leydig cells. Expression of the TXNRD1_v3 transcript was also found in several cancer cell lines (HCC1937, H23, A549, U1810, or H157), and in HeLa cells, it was induced by estradiol or testosterone treatments. Surprisingly, green fluorescent protein fusions with the complete TXNRD1_v3 protein or with only its Grx domain localized to distinct cellular sites in proximity to actin, and furthermore, had a potent capacity to rapidly induce cell membrane protrusions. Analyses of these structures suggested that the Grx domain of TXNRD1_v3 localizes first in the emerging protrusion and is then followed into the protrusions by actin and subsequently by tubulin. The results presented thus reveal that TXNRD1_v3 has a unique and distinct expression pattern in human cells and suggest that the protein can guide actin polymerization in relation to cell membrane restructuring.
A new inborn error of glycosylation due to a Cog8 deficiency reveals a critical role for the Cog1-Cog8 interaction in COG complex formation (2007)

The hetero-octameric conserved oligomeric Golgi (COG) complex is essential for the structure/function of the Golgi apparatus through regulation of membrane trafficking. Here, we describe a patient with a mild form of a congenital disorder of glycosylation type II (CDG-II), which is caused by a homozygous nonsense mutation in the hCOG8 gene. This leads to a premature stop codon resulting in a truncated Cog8 subunit lacking the 76 C-terminal amino acids. Mass spectrometric analysis of the N- and O-glycan structures identified a mild sialylation deficiency. We showed that the molecular basis of this defect in N- and O-glycosylation is caused by the disruption of the Cog1–Cog8 interaction due to truncation. As a result, Cog1 deficiency accompanies the Cog8 deficiency, preventing assembly of the intact, stable complex and resulting in the appearance of smaller subcomplexes. Moreover, levels of ß1,4-galactosytransferase were significantly reduced. The defects in O-glycosylation could be fully restored by transfecting the patient's fibroblasts with full-length Cog8. The Cog8 defect described here represents a novel type of CDG-II, which we propose to name as CDG-IIh or CDG caused by Cog8 deficiency (CDG-II/Cog8). &#13;\n
Photonic nano-antennas: Directive emission and quantum state transformation (2015)

We consider the general concept of quantum field quantization in the nano-antenna modeled as an atomic chain. We show that the transformation of quantum near-field to the far-field is accompanied by the transformation of the quantum state of light. As a result, transmitting and receiving antennas cannot be considered separately, which has no analogs in classical antennas. Such behavior stems from the transmitting antenna quantum state destruction via the signal detection by the receiving antenna.
Hybrid Organic–Inorganic Perovskite Superstructures for Ultrapure Green Emissions (2023)

All inorganic CsPbBr<sub>3</sub> superstructures (SSs) have attracted much research interest due to their unique photophysical properties, such as their large emission red-shifts and super-radiant burst emissions. These properties are of particular interest in displays, lasers and photodetectors. Currently, the best-performing perovskite optoelectronic devices incorporate organic cations (methylammonium (MA), formamidinium (FA)), however, hybrid organic-inorganic perovskite SSs have not yet been investigated. This work is the first to report on the synthesis and photophysical characterization of APbBr<sub>3</sub> (A = MA, FA, Cs) perovskite SSs using a facile ligand-assisted reprecipitation method. At higher concentrations, the hybrid organic-inorganic MA/FAPbBr<sub>3</sub> nanocrystals self-assemble into SSs and produce red-shifted ultrapure green emissions, meeting the requirement of Rec. 2020 displays. We hope that this work will be seminal in advancing the exploration of perovskite SSs using mixed cation groups to further improve their optoelectronic applications.
Fabrication of Cellulose Nanofibers from Parenchyma Cells of Pears and Apples (2011)

Cellulose nanofibers were isolated from parenchyma cells of pears and apples by one-time fibrillation using a grinding apparatus after the removal of matrix substances. The fibrillated cellulose samples were observed by field emission scanning electron microscopy, and were found to have a fine nano-structure. That is, the structure was uniform with an average width of approximately 18 nm and a high aspect ratio. These appearances were similar to those for nanofibers from wood. The fabricated nanofibers were characterized by FT-IR spectra and X-ray diffraction profiles, which showed that cellulose nanofibers were extracted, and the cellulose I crystal structure was maintained after a series of chemical treatments and grinding processing.
Impact of Surgical Waiting-List Times on Scoliosis Surgery (2014)

N/A.
Transparent Ceramics and Flexible Crystal Fibers for High Power Lasers (2013)

We report recent efforts to develop high power solid state lasers using Yb3+ and Ho3+ doped sesquioxide ceramics as well as the development of flexible cladded single-crystal fibers for high power single frequency fiber lasers.
Discovery of a Pyrrolopyrimidine (JH-II-127), a Highly Potent, Selective, and Brain Penetrant LRRK2 Inhibitor (2015)

Activating mutations in leucine-rich repeat kinase 2 (LRRK2) are present in a subset of Parkinson's disease (PD) patients and may represent an attractive therapeutic target. Here we report a 2-anilino-4-methylamino-5-chloropyrrolopyrimidine, JH-II-127 (18), as a potent and selective inhibitor of both wild-type and G2019S mutant LRRK2. Compound 18 substantially inhibits Ser910 and Ser935 phosphorylation of both wild-type LRRK2 and G2019S mutant at a concentration of 0.1-0.3 μM in a variety of cell types and is capable of inhibiting Ser935 phosphorylation in mouse brain following oral delivery of doses as low as 30 mg/kg.
EMC noise free endoscope using optical fiber communication technology (2008)

Recently, the number of pixels of an image sensor has reached more than one Mega in the field of video endoscopes, while analog signal transmission bands that use existing electric wires will face physical limitations from the perspective of signal bandwidth and EMC (Electro Magnetic Compatibility) noise. In order to solve these problems, we have developed a bi-directional digital optical communication endoscope system that employs both an image sensor and a single line optical fiber. In addition, due to the fiber's high-speed image signal transmission, we have incorporated a digital circuit for serial modulation and deserial demodulation. Consequently, we confirmed that transmission speeds of a 1Gbps downlink image signal and a 110Kbps uplink control signal were achieved as a result of simultaneous communication. We also designed and tested a compact, co-axial bi-directional optical transmitter and receiver module that can be built into the distal side of a scope. The optical communication module size is less than &phi;4&times;10mm. It was confirmed that this module could be installed in the distal side of a current endoscope.
Familial British dementia with amyloid angiopathy (2000)

Familial British dementia with amyloid angiopathy (FBD) is an autosomal dominant condition characterized by a dementia, progressive spastic tetraparesis and cerebellar ataxia with onset in the sixth decade. A point mutation in the BRI gene has been shown to be the genetic abnormality. Genealogical work with the large family originally reported by Worster-Drought and updated by Plant has identified nine generations dating back to the late eighteenth century. The pedigree now includes six living affected patients, 35 historical cases, and 52 descendants at risk of having inherited the disease. A common ancestor has been identified between the large pedigree and a case report of 'familial cerebellar ataxia with amyloid angiopathy'. An autopsy case from a separate family with an identical condition is described but no common ancestor with the large pedigree has been found. Case histories have been researched and updated in each pedigree. Eleven individuals at risk of FBD, aged between 44 and 56 years, agreed to undergo a clinical and neuropsychological assessment along with MRI brain imaging in order to clarify early diagnostic features. Five of the eleven were thought to show early clinical signs of the disease. Neurological examination was abnormal in three, with limb and gait ataxia and mild spastic paraparesis. Three had impaired recognition and recall memory and another had mild impairment of delayed visual recall. All affected individuals had an abnormal MRI of the brain, consisting of deep white-matter hyperintensity (T(2)-weighted scans) and lacunar infarcts, but no intracerebral haemorrhage. The corpus callosum was affected particularly, and in one patient it was severely atrophic.
A New Certificateless Proxy Re-encryption Scheme (2010)

In a proxy re-encryption (PRE) scheme, a semi-trusted proxy is given special information that allows it to transform cipher texts encrypted under Alice's public key into the different cipher texts that can be decrypted by Bob's secret key. In 2006, Green and Ateniese proposed identity-based proxy re-encryption schemes, in which cipher texts are transformed from one identity to another. Based on this, we propose a new construction for certificate less proxy re-encryption scheme and the corresponding security model in this paper. The scheme is proved secure against chosen-plaintext attack in the random oracle model assuming that an underlying problem related to the Decisional Bilinear Diffie-Hellman problem is computationally hard.
Improved CRT algorithm for class polynomials in genus 2 (2013)

We present a generalization to genus 2 of the probabilistic algorithm of Sutherland for computing Hilbert class polynomials. The improvement over the Brker-Gruenewald-Lauter algorithm for the genus 2 case is that we do not need to find a curve in the isogeny class whose endomorphism ring is the maximal order; rather, we present a probabilistic algorithm for "going up" to a maximal curve (a curve with maximal endomorphism ring), once we find any curve in the right isogeny class. Then we use the structure of the Shimura class group and the computation of .`; `/-isogenies to compute all isogenous maximal curves from an initial one.
Molecular Approach to Hypothalamic Rhythms: Isolation of Novel Indoleamine Receptor Genes (1993)

We have utilized polymerase chain reaction with primers corresponding to conserved amino acid sequences within membrane-spanning regions of known serotonin receptors to identify clones of four putative new indoleamine receptors. We have determined complete amino acid sequences of these four receptors, which fall into three subfamilies; two of these subfamilies are novel. The sites of expression within the brain have been determined for each of the genes. Expression in mammalian cells demonstrates that each new protein is a receptor for serotonin and that each has a distinct pharmacology when compared to known receptors. Two of the new receptors are coupled to cyclic adenosine monophosphate, one negatively (Gi) and one positively (Gs). The latter is a candidate for the serotonin receptor that mediates phase advances in circadian rhythms of the suprachiasmatic nucleus.
3D Printing of Poly‐ε‐Caprolactone (PCL) Auxetic Implants with Advanced Performance for Large Volume Soft Tissue Engineering (Adv. Funct. Mater. 24/2023) (2023)

Soft Tissue Engineering In article number 2215220, Scott J. Hollister, Michael E. Davis, and co-workers report, 3D printing of a novel architected auxetic with enhanced mechanical and biological performance. Specifically, the printed auxetics have high flexibility, permeability, and nonlinear deformation behavior as demonstrated through computational, mechanical, and biological analysis. These characteristics provide a great potential to create clinically viable implants for the reconstruction of large volume soft tissues.
Pentacene organic thin film transistors with anodized gate dielectric (2005)

A low temperature high quality gate dielectric process for bottom gate organic thin film transistors (OTFT) is introduced which is compatible to plastic substrates. The Al<sub>2</sub>O<sub>3 </sub>dielectric is grown from the aluminum gate electrode by anodic oxidation at room temperature and exhibits an exceptionally good electrical performance even for thin layers of 50nm. Finding an electrolyte which significantly reduces dielectric charges was instrumental for the desired OTFT application. The electrolyte and substrate dependent behaviour was characterized and compared to different dielectrics to point out the advantages of anodic oxidized aluminum. The characteristics of pentacene bottom contact OTFTs realized with anodized Al<sub>2</sub>O<sub>3</sub> gate dielectric on glass and plastic substrates are presented.
Population differences and domestication effects on mating and remating frequencies in Queensland fruit fly (2022)

Females of many insect species are unreceptive to remating for a period following their first mating. This inhibitory effect may be mediated by either the female or her first mate, or both, and often reflects the complex interplay of reproductive strategies between the sexes. Natural variation in remating inhibition and how this phenotype responds to captive breeding are largely unexplored in insects, including many pest species. We investigated genetic variation in remating propensity in the Queensland fruit fly, Bactrocera tryoni, using strains differing in source locality and degree of domestication. We found up to threefold inherited variation between strains from different localities in the level of intra-strain remating inhibition. The level of inhibition also declined significantly during domestication, which implied the existence of genetic variation for this trait within the starting populations as well. Inter-strain mating and remating trials showed that the strain differences were mainly due to the genotypes of the female and, to a lesser extent, the second male, with little effect of the initial male genotype. Implications for our understanding of fruit fly reproductive biology and population genetics and the design of Sterile Insect Technique pest management programs are discussed.
ChemInform Abstract: An Al(OTf)3‐Catalyzed Environmentally Benign Process for the Propargylation of Indoles. (2012)

Abstract The reaction proceeds in high yields and with excellent selectivity.
Particle swarm optimization for Mobility Load Balancing SON in LTE networks (2014)

This paper presents a self-optimizing solution for Mobility Load Balancing (MLB). The MLB-SON is performed in two phases. In the first, a MLB controller is designed using Multi-Objective Particle Swarm Optimization (MO-PSO) which incorporates a priori expert knowledge to considerably reduce the search space and optimization time. The dynamicity of the optimization phase is addressed. In the second phase, the controller is pushed into the base stations to implement the MLB SON. The method is applied to dynamically adapt Handover Margin parameters of a large scale LTE network in order to balance traffic of the network eNodeBs. Numerical results illustrate the benefits of the proposed solution.
Capture configuration for image-based street walkthroughs (2004)

Image-based rendering for walkthroughs in a virtual environment has many advantages over a geometry-based approach, due to the fast construction of the environment and, photo-realistic rendered results, etc. However, since light field approaches are limited to a closed space, they cannot be directly applied to large and complex street environments. Accordingly, the current paper, presents an image-based rendering method that can handle a large-scale scene, thereby, allowing street walkthroughs with light field style rendering. First, the problem of capture configuration is described based on the previous work. Then an efficient sampling configuration of image sequences is presented, and the efficiency of the proposed method demonstrated with several experiments.
Novel through silicon via exposure process comprising Si/Cu grinding, electroless Ni–B plating, and wet etching of Si (2014)

We proposed a novel through silicon via (TSV) exposure process comprising Si/Cu grinding, electroless Ni–B plating, and wet etching of Si. To grind Cu and Si simultaneously without burning and smearing Cu, we used a novel grinding wheel (vitrified-bond type) and performed in situ cleaning of grinding wheel by using a high pressure micro jet. The electroless Ni–B plating was performed to cover the Cu surface and prevent Cu etching during wet etching of Si. The wet etching of Si was performed using KOH solution. By time-of-flight secondary ion mass spectrometry, we investigated the presence of metal contaminants in the Si region between TSVs after being subjected to the proposed TSV-exposed process. The results showed that this process suppressed the generation of Cu contaminants below 1.0 × 1011 atoms/cm2.
Effect of DMDBS (3 : 2, 4‐bis(3,4‐dimethyldibenzylidene) sorbitol) and NA11 (sodium 2,2′‐methylene‐bis(4,6‐di‐tertbutylphenyl)‐phosphate) on electret properties of polypropylene filaments (2013)

ABSTRACT Polypropylene (PP) composite filaments containing two different nucleating agents—DMDBS (3 : 2, 4‐bis(3,4‐dimethyldibenzylidene) sorbitol) and NA11 (sodium 2,2′‐methylene‐bis(4,6‐di‐tertbutylphenyl)‐phosphate) were melt spun to modify polymer electrostatic charging characteristics. Sample filaments were charged with a corona instrument and their surface potentials were measured. Initial surface potential as well as potential stability was monitored through an accelerated decay procedure. NA11 was found to be more efficient as an electret additive leading to a 50% increase in charge stability. Filaments with DMDBS exhibited a faster decay. Charging at elevated temperatures resulted in enhanced charge density and stability for both additives. The fiber microstructure was examined by Wide Angle X‐ray Diffraction and Differential Scanning Calorimetry. Rather than reducing the crystal sizes, X‐Ray diffractograms suggest that the crystal size increases with the addition of nucleating agents, while the degree of crystallinity appears to remain unaltered. © 2013 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 130: 2068–2075, 2013