gebhart/patrepeval huggingface dataset:
Quantitative XPS determination of Pt coverage on SrBi 2 Ta 2 O 9 thin films for ferroelectric memories (2001)

Abstract X‐ray photoelectron spectroscopy measurements were conducted for a spin‐coated SrBi 2 Ta 2 O 9 (SBT) system with sputter‐deposited 5 nm thick Pt film on it. The spectral peaks were analysed quantitatively under several surface structure models. The XPS results also were compared with SEM observation results. The Pt coverage was lowest (∼15%) on a specimen prepared from complexed alkoxide solution followed by a second annealing at 800 °C in O 2 and sintering in a hydrogen atmosphere at 400 °C (H 2 sintering), whereas it was highest (97%) on a specimen prepared from a sol–gel solution without any other treatment except crystallization. From regression analysis of all the data, the effects of the solution property, second annealing and H 2 sintering on Pt coverage were evaluated. It was found that the effect of the second annealing in O 2 was very large, whereas that of the H 2 sintering does not give a large effect but it certainly causes a decrease in the apparent Pt coverage. Even the difference in solution for spin‐coating has an influence on the Pt coverage, i.e. sol–gel and complex solutions give the highest and lowest values, respectively. It was clarified that the Pt‐coverage had a clear correlation with fabrication factors, such as solution property, second annealing in O 2 and H 2 sintering. There was an excellent agreement between XPS and SEM results. Copyright © 2001 John Wiley &amp; Sons, Ltd.
Sequence analysis of a human gene responsible for drug resistance: a rapid method for manual and automated direct sequencing of products generated by the polymerase chain reaction. (1989)

We developed a system for rapid, manual and automated sequence analysis by utilizing and modifying methods used in conjunction with the polymerase chain reaction (PCR). We are using these techniques to detect single base mutations in the dihydrofolate reductase (DHFR) gene giving rise to methotrexate (MTX) resistance of tumor cells obtained from patients with malignancies. Amplifying in vitro both genomic DNA and transcripts of the human DHFR we are able to reproducibly generate single-stranded templates. Utilizing [alpha-35S]dATP and both the universal and reverse sequencing primers we obtain sequence information from either strand. The methods described have been successfully used for automated sequencing with the Applied Biosystems Model 370A Sequencer using both modified T7 DNA polymerase and Taq I. DNA polymerase for dideoxy-termination sequencing. The use of this methodology to detect a single base change in a human colon carcinoma cell line, HCT-8, is illustrated.
18.4L: Late‐News Paper : Full Color Flexible Top‐emission AMOLED Display on Polyethylene Naphthalate (PEN) Foil with Metal Oxide TFTs Backplane (2013)

Abstract We have developed a full color flexible top‐emission AMOLED display with 80 ppi resolution using In‐Ga‐Zn‐O TFT backplane on PEN foil under the maximum process temperature of 150 o C. Notwithstanding the low processing temperature, the TFTs with SiOx passivation layer show high reliability with V TH shift of less than 0.2 V at 10,000 seconds under bias‐stress of −10 V.
Electrochemical Synthesis of MII Complexes with a Schiff Base containing an Amido Group. Crystal Structure of a Cobalt(II) Complex with a Reorganised Ligand (2005)

Abstract M(HL)(H 2 O) n complexes have been obtained by the electrochemical reaction of Fe, Co, Ni, Cu, Zn and Cd anodes with the potentially pentadentate and trianionic asymmetrical Schiff base 3‐aza‐ N ‐{2‐[1‐aza‐2‐(5‐nitro‐2‐hydroxylphenyl)‐vinyl]phenyl}‐4‐(5‐nitro‐2‐hydroxyphenyl)but‐3‐enamide (H 3 L), containing a hard amido donor atom. The complexes have been characterized by elemental analysis, mass spectrometry, IR and 1 H NMR spectroscopies, magnetic measurements and molar conductivities. Co(HL)(H 2 O) ( 2 ) has been found to rearrange in DMF solution into a crystallographically solved octahedral complex, CoL 1 (H 2 O) 2 ( 7 ) [where H 2 L 1 is the symmetrical Schiff base ligand N,N′ ‐(1,2‐phenylene)‐bis(5‐nitro‐3‐hydroxysalicylidenimine)]. A hydrolysis mechanism is discussed to explain this rearrangement.
On the lifetimes of Rydberg states probed by delayed pulsed field ionization (1994)

We present a simple model to evaluate the degree of l and ml mixing in high Rydberg states that results from perturbations caused by weak, homogeneous dc electric fields and static ions. This model predicts the lifetime of these states qualitatively and explains several seemingly contradictory observations obtained using zero-kinetic-energy (ZEKE) photoelectron spectroscopy. The presence of a small homogeneous dc electric field and a few ions in the sample volume causes ml mixing in general as well as l mixing, both of which contribute to the lengthening of the lifetimes. Consequently, the lifetime lengthening appears to be insensitive to the sample pressure. The effect of the dc electric field on the lifetime is complex. Although the electric field results in l mixing, with increasing field strength it inhibits ml mixing, and, at still higher field strength, induces ionization. The variation of the lifetimes with ion concentration is also complicated. At low ion concentration, the ml mixing varies across the Stark manifold of Rydberg states that belong to the same principal quantum number, so that different states have different lifetimes. At higher ion concentration, l and ml mixing are more uniform, which lengthens the lifetimes and makes them more similar across the Stark manifold. At still higher concentrations, collisional ionization dominates, which shortens the lifetimes.
Intermittent Positive Pressure Breathing (1996)

Nilsestuen, Jon PhD, RRT; Fink, James B. MBA, RRT; Stoller, James K. MD; Volpe, James RRT; Witek, Theodore Jr DrPH, RPFT, RRT Author Information
Single Cell RNA-sequencing Identifies Novel Bone Marrow Derived Myeloid Cells in Glioblastoma Associated with Tumor Aggression (2020)

Jackson, Christina MD; Cherry, Christopher; Bom, Sadhana; Zhang, Hao; Choi, John BS; Yegnasubramanian, Vasan; Elisseeff, Jennifer; Pardoll, Drew; Lim, Michael MD Author Information
Nonlinear Modeling of Azimuth Error for 2D Car Navigation Using Parallel Cascade Identification Augmented with Kalman Filtering (2010)

Present land vehicle navigation relies mostly on the Global Positioning System (GPS) that may be interrupted or deteriorated in urban areas. In order to obtain continuous positioning services in all environments, GPS can be integrated with inertial sensors and vehicle odometer using Kalman filtering (KF). For car navigation, low-cost positioning solutions based on MEMS-based inertial sensors are utilized. To further reduce the cost, a reduced inertial sensor system (RISS) consisting of only one gyroscope and speed measurement (obtained from the car odometer) is integrated with GPS. The MEMS-based gyroscope measurement deteriorates over time due to different errors like the bias drift. These errors may lead to large azimuth errors and mitigating the azimuth errors requires robust modeling of both linear and nonlinear effects. Therefore, this paper presents a solution based on Parallel Cascade Identification (PCI) module that models the azimuth errors and is augmented to KF. The proposed augmented KF-PCI method can handle both linear and nonlinear system errors as the linear parts of the errors are modeled inside the KF and the nonlinear and residual parts of the azimuth errors are modeled by PCI. The performance of this method is examined using road test experiments in a land vehicle.
Biochemical characterization and structure determination of a potent, selective antibody inhibitor of human MMP9 (2017)

Matrix metalloproteinase 9 (MMP9) is a member of a large family of proteases that are secreted as inactive zymogens. It is a key regulator of the extracellular matrix, involved in the degradation of various extracellular matrix proteins. MMP9 plays a pathological role in a variety of inflammatory and oncology disorders and has long been considered an attractive therapeutic target. GS-5745, a potent, highly selective humanized monoclonal antibody inhibitor of MMP9, has shown promise in treating ulcerative colitis and gastric cancer. Here we describe the crystal structure of GS-5745·MMP9 complex and biochemical studies to elucidate the mechanism of inhibition of MMP9 by GS-5745. GS-5745 binds MMP9 distal to the active site, near the junction between the prodomain and catalytic domain, and inhibits MMP9 by two mechanisms. Binding to pro-MMP9 prevents MMP9 activation, whereas binding to active MMP9 allosterically inhibits activity.
Activity-Based DNA-Encoded Library Screening (2019)

Robotic high-throughput compound screening (HTS) and, increasingly, DNA-encoded library (DEL) screening are driving bioactive chemical matter discovery in the postgenomic era. HTS enables activity-based investigation of highly complex targets using static compound libraries. Conversely, DEL grants efficient access to novel chemical diversity, although screening is limited to affinity-based selections. Here, we describe an integrated droplet-based microfluidic circuit that directly screens solid-phase DELs for activity. An example screen of a 67 100-member library for inhibitors of the phosphodiesterase autotaxin yielded 35 high-priority structures for nanomole-scale synthesis and validation (20 active), guiding candidate selection for synthesis at scale (5/5 compounds with IC<sub>50</sub> values of 4-10 μM). We further compared activity-based hits with those of an analogous affinity-based DEL selection. This miniaturized screening platform paves the way toward applying DELs to more complex targets (signaling pathways, cellular response) and represents a distributable approach to small molecule discovery.
Ionizing Radiation Sensor Utilizing Radiophotoluminescence in Ag+-Activated Phosphate Glass and Its Application to Environmental Radiation Monitoring (2010)

1Oarai Research Center, Chiyoda Technol Corporation, 3681 Narita-cho, Oarai-machi, Higashi-ibaraki-gun, Ibaraki 311-1313, Japan 2Advanced Materials. Science Research and Development Center, Kanazawa Institute of Technology, 3-1 Yatsukaho, Hakusann-shi, Ishikawa 924-0838, Japan 3Nature Science, Kanazawa University, Kakuma-cho, Kanazawa, Ishikawa 920-1192, Japan 4Division of Advanced Crystal Materials, Tohoku University, Katahira, Sendai, Miyagi 980-0557, Japan 5Department of Materials Chemistry, Graduate School of Engineering, Kyoto University, A3-119 Katsura, Kyoto-University, Nishikyo-ku, Kyoto-shi, Kyoto 615-8510, Japan
Spatially-resolved mid-infrared spectroscopy of IC 5063 (2007)

"N-band spectroscopy of the radio strongSeyfert 2 active galaxy IC 5063 (z=0.0110)was obtained using Gemini South in conjunc-tion with the Thermal-Region Camera Spec-trograph (T-ReCS; Telesco et al. 1998). T-ReCS uses a Raytheon 320x240 pixel SiAsIBC array, at a plate scale of 0.08900 pixel-1.The observations were conducted on thenights of UT 2005 July 7 and 9 using thestandard chop-nod technique to remove thetime-variable sky background, telescope ther-mal emission, and the so-called 1/f detectornoise. A 0.6700 wide slit was used alignedalong the position angle of the radio axis at305o(Morganti et al. 1998) and close to theextended narrow line emission region (ENLR)axis at 303_(Colina et al. 1991). The total on-source integration time was 1212 seconds."
Predicting missing biomarker data in a longitudinal study of Alzheimer disease (2012)

The missing data are not missing completely at random in ADNI and likely conditional on certain features in addition to cognitive function. Missing data predictors vary across biomarkers and even MCI and AD groups do not share the same missing data pattern. Understanding the missing data structure may help in the design of future longitudinal studies and clinical trials in AD.
The signal transduction pathway involved in the migration induced by a monocyte chemotactic cytokine (1991)

Recombinant monocyte-chemotactic and activating factor (rMCAF; alternative acronyms MCP-1, TDCF, human JE) induced migration of human monocytes across polycarbonate or nitrocellulose filters. Maximal induction of migration was observed at a concentration of 10 ng/ml (10(-9) M). Checkerboard analysis revealed that rMCAF elicited true gradient-dependent chemotactic migration, although a gradient independent chemokinetic effect was observed at low concentrations (1-5 ng/ml). rMCAF caused a rapid (less than 5 s) and transient (approximately 1.5 min) increase of free cytosolic Ca2+ ions, as assessed by the fura-2 probe. No Ca2+ increase was detected in neutrophils or lymphocytes stimulated by rMCAF. Studies conducted in the absence of extracellular Ca2+ or in the presence of Ni2+ (an inhibitor of Ca2+ influx) suggested that the increase of intracellular Ca2+ induced by rMCAF is dependent on the influx of extracellular Ca2+ through plasma membrane channels. Bordetella pertussis toxin inhibited the intracellular Ca2+ elevation and chemotaxis caused by rMCAF. The possible involvement of Ca(2+)-dependent protein kinases in rMCAF signaling pathway(s) was explored using inhibitors. Inhibitors of GMP-dependent kinase and myosin L chain kinase had no effect on rMCAF-induced monocyte migration. In contrast, protein kinase C/cAMP-dependent kinase inhibitors (such as, C-I, H-7, HA-1004, KT5720, and Staurosporine) markedly decreased rMCAF induced chemotaxis suggesting the involvement of a serine/threonine protein kinase, possibly protein kinase C, in rMCAF signaling pathway.
Acoustic effect and correlated errors in soliton information transmission (2005)

Summary form only given. Solitons that propagate in an optical fiber experience timing jitter that limits both the bit rate and the information transmission distance. This timing jitter is caused by several effects: the Gordon-Haus effect, the polarization effect, and the acoustic effect. At bit rates in excess of 10 Gbit/s, the acoustic effect becomes the dominant cause of the timing jitter at distances greater than a few thousand kilometers. The acoustic effect is created by the large transverse gradient of the electric fields in the optical fiber due to the soliton pulses. These large field gradients electrostrictively excite acoustic waves that influence later solitons. The acoustic wave perturbs the effective refractive index of the fiber, leading to changes in the frequencies and temporal locations of the solitons.
9 Neurogenesis in the Adult Hippocampus (2008)

As noted previously in this volume, adult neurogenesis is a process, not an event. Adult neurogenesis comprises a series of sequential developmental events that are all necessary for the generation of new neurons under the conditions of the adult brain. In the original publications on adult neurogenesis, the precursor cell population from which neurogenesis originates was identified only by the detection of proliferative activity and the absence of mature neuronal markers (Altman and Das 1965; Kaplan and Hinds 1977; Cameron et al. 1993; Kuhn et al. 1996). The new neurons, in contrast, were identified by the presence of mature neuronal markers in cells that had been birthmarked with the thymidineoder BrdU (bromodeoxyuridine) method (see Chapters 2 and 3) a couple of weeks earlier. The expression of the polysialilated neural cell adhesion molecule (PSA-NCAM) with neurogenesis has been noted early but could not be clearly linked to either proliferation or mature stage (Seki and Arai 1993a,b). PSA-NCAM expression was the first indication of the developmental events that take place, filling the gaps between the start and endpoint of development. Today, we have quite detailed knowledge about the course of neuronal development in the adult hippocampus, and although many detailed questions remain open, a clear overall picture has emerged (Kempermann et al. 2004; Abrous et al. 2005; Ming and Song 2005; Lledo et al. 2006). Although we coarsely talk about neurogenesis in the hippocampus, it should be noted that neurogenesis occurs only in the dentate gyrus (DG), not other regions; in an...
Identification of a Bacillus subtilis spo0H allele that is necessary for suppression of the sporulation-defective phenotype of a spo0A mutation (1995)

A mutation in Bacillus subtilis spo0A codon 97 suppressed the sporulation defect caused by the spo0A9V mutation. The suppressor activity of the codon 97 mutation was evident only in the presence of a novel spo0H allele. Our results suggest that the spo0A gene product interacts with the sigma factor subunit of RNA polymerase.
Identification of the Minimum Combination of Serum microRNAs to Predict the Recurrence of Colorectal Cancer Cases (2022)

We identified ideal combinatorial miRNAs to predict CRC recurrence.
Measurement techniques for laser parameters relevant to materials processing (2005)

Many micromachining operations, particularly in the electronics sector, utilize pulsed solid-state UV lasers. These processes demand high levels of stability, as the yield and quality relate directly to the repeatability of each laser pulse. Critical stability issues arise with single-pulse processes (e.g. repair), situations requiring bursts of pulses (e.g. drilling), and continuous pulsing applications (e.g. cutting). To realize optimal stability specific design choices must be made, certain transient problems must be solved, and pulse energy measurements must be standardized. Solid-state UV lasers originate as infrared lasers, and nonlinear optics converts the infrared to the UV. This conversion introduces instability. Performing the conversion within the infrared laser cavity suppresses the instability, relative to performing the conversion outside of the laser cavity. We explain this phenomenon. Ideally, a versatile and stable solid-state laser can generate pulses in many formats. Thermal effects tend to prevent this versatile ideal, resulting in transient problems (unstable pulse trains), or less than optimal performance when the laser is pulsing continuously. Many methods of measuring pulse energy exist. Each method can produce surprisingly different results. We compare various techniques, discuss their limitations, and suggest an easily implemented pulse energy stability measurement.
Constitutive PI3-K activity is essential for proliferation, but not survival, of Theileria parva-transformed B cells (2000)

Theileria is an intracellular parasite that causes lymphoproliferative disorders in cattle, and infection of leucocytes induces a transformed phenotype similar to tumour cells, but the mechanisms by which the parasite induces this phenotype are not understood. Here, we show that infected B lymphocytes display constitutive phosphoinositide 3-kinase (PI3-K) activity, which appears to be necessary for proliferation, but not survival. Importantly, we demonstrate that one mechanism by which PI3-K mediates the proliferation of infected B lymphocytes is through the induction of a granulocyte-monocyte colony-stimulating factor (GM-CSF)-dependent autocrine loop. PI3-K induction of GM-CSF appears to be at the transcriptional level and, consistently, we demonstrate that PI3-K is also involved in the constitutive induction of AP-1 and NF-kappaB, which characterizes Theileria-infected leucocytes. Taken together, our results highlight a novel strategy exploited by the intracellular parasite Theileria to induce continued proliferation of its host leucocyte.
ChemInform Abstract: SOLAR ENERGY STORAGE. PRODUCTION OF HYDROGEN BY 546‐NM IRRADIATION OF A DINUCLEAR RHODIUM(I) COMPLEX IN ACIDIC AQUEOUS SOLUTION (1977)

Abstract Nach der Quantenausbeute von 0,0040 i0,0002 der durch Wasserstoff nicht inhibierten Photoreaktion (siehe Schema) erscheint Sonnenenergienutzung zur Wasserstoffproduktion möglich, wobei die thermische Rückreaktion mehrere Tage benötigt.
Longitudinal and transverse frictional drag in graphene/LaAlO3/SrTiO3 heterostructures (2022)

Heterostructures composed of different layered materials provide novel opportunities to investigate the electronic correlations between them. Here we investigate frictional drag between graphene and ${\mathrm{LaAlO}}_{3}/{\mathrm{SrTiO}}_{3}$ (LAO/STO) heterostructures. The LAO/STO layer underneath the graphene is rendered conductive using conductive atomic force microscope (c-AFM) lithography, creating a two-layer system in which the LAO serves as an ultrathin ($&lt;$2 nm) insulating barrier. By sourcing current in both the STO layer and graphene layer, Coulomb drag is studied in a wide range, from an STO superconducting region to a graphene quantum Hall region. Pronounced fluctuations in the frictional drag resistance are observed when the STO is superconducting. A large enhancement of drag resistance is observed when the STO becomes superconducting. Pronounced stripelike oscillations in the frictional drag appear in the quantum Hall region, both along the main channel and the transverse (Hall) configuration. The behavior is consistent with numerical simulations that model energy and momentum transfer from the STO layer to the graphene layer. These help to create a platform for graphene-based metamaterials using the programmable LAO/STO interface.
In Vivo Dark-Field Radiography for Early Diagnosis and Staging of Pulmonary Emphysema (2015)

X-ray dark-field radiography can reliably visualize different stages of emphysema in vivo and demonstrates significantly higher diagnostic accuracy for early stages of emphysema than conventional attenuation-based radiography.
Force mapping in epithelial cell migration (2005)

We measure dynamic traction forces exerted by epithelial cells on a substrate. The force sensor is a high-density array of elastomeric microfabricated pillars that support the cells. Traction forces induced by cell migration are deduced from the measurement of the bending of these pillars and are correlated with actin localization by fluorescence microscopy. We use a multiple-particle tracking method to estimate the mechanical activity of cells in real time with a high-spatial resolution (down to 2 microm) imposed by the periodicity of the post array. For these experiments, we use differentiated Madin-Darby canine kidney (MDCK) epithelial cells. Our data provide definite information on mechanical forces exerted by a cellular assembly. The maximum intensity of the forces is localized on the edge of the epithelia. Hepatocyte growth factor promotes cell motility and induces strong scattering activity of MDCK cells. Thus, we compare forces generated by MDCK cells in subconfluent epithelia versus isolated cells after hepatocyte growth factor treatment. Maximal-traction stresses at the edge of a monolayer correspond to higher values than those measured for a single cell and may be due to a collective behavior.
Magnetic modeling of a high-power three phase bi-directional IPT system (2011)

The demand for high power and bi-directional Inductive Power Transfer (IPT) systems is on the rise due mainly to applications such as electric vehicles (EVs) and vehicle-to-grid (V2G) systems. Three phase bi-directional IPT systems can be considered as a viable option for high power applications as they are more efficient especially at elevated power levels due to lower track currents and lower DC ripple currents in comparison to single-phase bi-directional IPT systems. This paper proposes a new IPT system that adopts a three-phase magnetic circuit for both primary and secondary sides of the system. Analyses related to design of the magnetic circuit for a 10 kW system are presented and validated by 3D simulations using JMAG Studio 10.0™ for four different magnetic circuit configurations. Based on the results, the most effective design is used for further simulations in MATLAB Simulink environment to show that the proposed three-phase IPT system is capable of delivering 10 kW as per design specifications.