gebhart/patrepeval huggingface dataset:
A PERTURBATION-BASED INTERVENTION IMPROVES GAIT STABILITY AND COGNITIVE PERFORMANCE IN OLDER ADULTS (2017)

Normal aging is associated with decline in both physical and cognitive functions. This contributes to an increased risk for falls, one of the most common and serious problem in late life. Physical exercise can marginally improve balance, gait and cognitive functions. In order to specifically target the neuromuscular skills required for fall prevention, new training paradigms that strengthen the control of compensatory responses after balance perturbations are required. To date, it is unknown if these training paradigms are also able to improve the cognitive functioning. We have developed a novel cable-driven robot that can apply multidirectional waist-pull perturbations while walking. A case-control study was performed on sixteen older adults to test the hypothesis that a single perturbation-based balance training session would be more effective than normal walking alone to improve (i) balance reactions to perturbations not experienced during the training; (ii) gait stability during unperturbed walking; and (iii) cognitive performance in terms of speed and executive functioning. Results confirmed that only participants trained with repeated perturbations showed acute effects of increases stability, both during walking and while reacting to novel perturbations, and superior performance in the Symbol Digit Modalities Test. Attention may have been primed through the perturbations or were linked with stability improvements. Even though we are unable to describe the underlying mechanisms mediating the cognitive and physical impairment, we envision to implement a task-oriented balance training program aimed at improving human aging trajectories in terms of balance, gait and cognitive functioning, thus reducing older adults’ risk of falling.
ChemInform Abstract: Biologically Active Sesterterpenes from a New Caledonian Marine Sponge Hyrtios sp. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Vaskuläres Immuntargeting von anti-PECAM/Katalase-Konjugaten ins pulmonale Endothel verbessert die Funktion der Spenderlungen bei der Lungentransplantation in Schweinen (2008)

Einleitung: Der Spenderpool bei Lungentransplantation könnte durch eine so genannte "Non-heart-beating" (NHB) Spende erweitert werden. Durch die zusätzliche Warmischämie bei diesen Spendern entsteht allerdings ein erhöhter Reperfusionschaden im pulmonalen Endothel, da dort vermehrt "reactive oxygen species" produziert werden.
Isolation and characterization of the first host recognition substance for parasitic angiosperms (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIsolation and characterization of the first host recognition substance for parasitic angiospermsDavid G. Lynn, John C. Steffens, Vinayak S. Kamut, David W. Graden, Jeffrey Shabanowitz, and James L. RiopelCite this: J. Am. Chem. Soc. 1981, 103, 7, 1868–1870Publication Date (Print):April 1, 1981Publication History Published online1 May 2002Published inissue 1 April 1981https://pubs.acs.org/doi/10.1021/ja00397a062https://doi.org/10.1021/ja00397a062research-articleACS PublicationsRequest reuse permissionsArticle Views183Altmetric-Citations53LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Evolving heterochrony for cellular differentiation using vector field embryogeny (2010)

Heterochrony is the evolutionary change of rates and timing of developmental processes.Many artificial evolutionary development systems have the ability to produce heterochrony implicitly.However, few systems have the ability to employ heterochronic change as direct evolutionary means, i.e. to directly change heterochronic features of the developmental program.In this paper, we present and investigate a system that can directly modify heterochronic features of its basic dynamics.We show how heterochrony can be included in a novel developmental framework called vector field embryogeny, and investigate the benefit of direct evolution of heterochronic change for four different cellular differentiation tasks.
A Bidirectional Acid-Base Charging Model for Triboelectrification: part II. Experimental Verification by Inverse Gas Chromatography and Charging of Metal Oxides (2006)

Inverse gas chromatography (IGC) has been applied to study the surface properties of developer materials, measuring acid, base, and dispersion interactions. Model carrier and toner particles were prepared, where the toner was blended with various nano-particulate metal oxide surface additives: Silica, titania, and alumina. Toner charging was determined with these surface additive formulations. IGC was used to characterize carrier and additive surface chemistry. Results from IGC were evaluated with respect to toner charge and to metal oxide work functions. A correlation was found between IGC-determined surface acid-base interaction parameters of the developer materials, and their work functions and triboelectric charge. Together, the IGC, work function, and charging results strongly support a work function model for developer charging, where the work function is determined by the acid and base properties of the developer components. Thus, as the ratio of the acid to base interaction parameters of the metal oxide surface additive increased, toner charge became more negative. The results are in quantitative agreement with the surface states charging model proposed in the companion paper in this series.
Liver Hemostasis With High‐Intensity Ultrasound (2004)

High-intensity focused ultrasound appears to provide long-lasting hemostasis of acute liver injury. Healing and repair mechanisms after high-intensity focused ultrasound application appear to be intact.
Mesenchymal Stromal Cells and Exosomes: Progress and Challenges (2020)

Due to their robust immunomodulatory capabilities, mesenchymal stem/stromal cells (MSCs) have been used as a cellular therapy for a number of human diseases. Part of the mechanism of action of MSCs is the production of extracellular vesicles (EVs) that contain proteins, nucleic acids, and lipids that transmit signals to recipient cells that change their biologic behavior. This review briefly summarizes the development of MSCs as a treatment for human diseases as well as describes our present understanding of exosomes; how they exert their effects on target cells, and how they are differentiated from other EVs. The current treatment paradigm for acute radiation syndrome (ARS) is discussed, and how MSCs and MSC derived exosomes are emerging as treatment options for treating patients after radiation exposure. Other conditions such as graft-versus-host disease and cardiovascular disease/stroke are discussed as examples to highlight the immunomodulatory and regenerative capacity of MSC-exosomes. Finally, a consideration is given to how these cell-based therapies could possibly be deployed in the event of a catastrophic radiation exposure event.
Faculty Opinions recommendation of Proportion of never smokers among men and women with lung cancer in 7 US states. (2020)

No abstract available PMID: 33270100
Management of Gastrointestinal Mucositis Due to Cancer Therapies in Pediatric Patients: Results of a Case Series with SAMITAL ® (2012)

Results from this case series suggest that SAMITAL(®) may play an important role in the prevention and treatment of chemotherapy-induced gastrointestinal mucositis in children and adolescents and as such warrants investigation in controlled studies.
Stone Culture Positive Veillonella in Analysis of Calcium-Based Stones: A Case Report (2020)

<b><i>Background:</i></b> Calcium-based urinary stones rarely grow bacteria on stone culture. The presence of an anaerobic bacteria is even more uncommon. We present a case of <i>Veillonella</i> growth from a primarily calcium phosphate-based urinary stone culture. <b><i>Case Presentation:</i></b> A 56-year-old Caucasian woman presented with urosepsis and bilateral nephrolithiasis. A nephrostomy tube was emergently placed in the left kidney. After resolution of her urosepsis, she underwent a left percutaneous nephrolithotomy. The stone culture grew <i>Veillonella</i>, a gram-negative anaerobe. <b><i>Conclusion:</i></b> Growth of anaerobic bacteria, such as <i>Veillonella</i>, on stone culture of a calcium-based stone is a rare occurrence; the mechanism of this association remains unexplained.
A Rare Case of Ischemic Colitis Due to an Inferior Mesenteric Vascular Anomaly Leading to Steal Phenomenon (2017)

Introduction: Inferior mesenteric arteriovenous fistula (IMAVF) is a rare disorder that can lead to ischemic colitis and portal hypertension. A vascular anomaly as a cause of mesenteric steal phenominon resulting in ischemic colitis is rare. As far as we are aware only 14 cases of IMAFs exist in the English literature, and only one has been associated with ischemic colitis. We aim to present a case of a vascular anomaly with steal phenomenon in an elderly male leading to ischemia in the watershed area of his colon.Figure: IMA, fistula, and larger bore draining veins.Case Description: The patient is a 74-year-old male with a negative screening colonoscopy a year prior who presents for abdominal pain, diarrhea and bright red blood per rectum. He has a medical history consisting of a left inguinal hernia repair fifteen years ago, HLD, peripheral neuropathy and BPH. Initial CT imaging and sigmoidoscopy with biopsies revealed ischemic colitis at the watershed area of the splenic flexure. He initially improved and was discharged home. However, two weeks later he represented to the hospital with complaints of continual voluminous diarrhea, abdominal discomfort and lethargy. He was found to have anemia and hypolbuminemia. The patient subsequently underwent an abdomen and pelvis angiogram which demonstrated an AVF arising between the inferior mesenteric artery and venous mesenteric branches within the midline pelvis. The procedure was technically successful with glue embolization of 3 separate feeding arteries to the malformation; however, there was continued filling of the arteriovenous fistula because of multiple feeding vessels. The patient's symptoms improved and he was scheduled to have an outpatient surgical resection of his sigmoid colon. Discussion: AVFs of the inferior mesenteric vessels are rare. Of the 14 reported cases we found, 6 were congenital and 8 were a result of late post operative complications of colonic resection. In no reported study was a laparoscopic inguinal hernia repair with mesh noted. Two noted compilations of AVFs are ischemic colitis and portal hypertension. Our patient was noted to have both. Patient can present with ascites, bleeding, esophageal varices, pain, diarrhea, malabsorption and bowel ischemia. IMAFs have been recognized by some authors as a new factor predisposing to non-occlusive ischemic colitis. Angiography remains the gold standard in the diagnosis of AVFs as well as providing an option of intervention with endovascular embolization.Figure: CT sagittal view of fistula and ascites from portal hypertension.Figure: AVM post embolization with using n-BCA glue in a 1:3 ratio mixed with Ethiodol and tantalum powder.
Regulatory volume decrease in the presence of HCO3- by single osteosarcoma cells UMR-106-01. (1992)

The technique for the simultaneous recording of cell volume changes and pHi in single cells was used to study the role of HCO3- in regulatory volume decrease (RVD) by the osteosarcoma cells UMR-106-01. In the presence of HCO3-, steady state pHi is regulated by Na+/H+ exchange, Na+ (HCO3-)3 cotransport and Na(+)-independent Cl-/HCO3- exchange. Following swelling in hypotonic medium, pHi was reduced from 7.16 +/- 0.02 to 6.48 +/- 0.02 within 3.4 +/- 0.28 min. During this period of time, the cells performed RVD until cell volume was decreased by 31 +/- 5% beyond that of control cells (RVD overshoot). Subsequently, while the cells were still in hypotonic medium, pHi slowly increased from 6.48 +/- 0.02 to 6.75 +/- 0.02. This increase in pHi coincided with an increase in cell volume back to normal (recovery from RVD overshoot or hypotonic regulatory volume increase (RVI)). The same profound changes in cell volume and pHi after cell swelling were observed in the complete absence of Cl- or Na+, providing HCO3- was present. On the other hand, depolarizing the cells by increasing external K+ or by inhibition of K+ channels with quinidine, Ba2+ or tetraethylammonium prevented the changes in pHi and RVD. These findings suggest that in the presence of HCO3-, RVD in UMR-106-01 cells is largely mediated by the conductive efflux of K+ and HCO3-. Removal of external Na+ but not Cl- prevented the hypotonic RVI that occurred after the overshoot in RVD. Amiloride had no effect, whereas pretreatment with 4,4'-diisothiocyanostilbene-2,2'-disulfonic acid (DIDS) strongly inhibited hypotonic RVI. Thus, hypotonic RVI is mediated by a Na+(out)-dependent, Cl(-)-independent and DIDS-inhibitable mechanism, which is indicative of a Na+(HCO3-)3 cotransporter. This is the first evidence for the involvement of this transporter in cell volume regulation. The present results also stress the power of the new technique used in delineating complicated cell volume regulatory mechanisms in attached single cells.
<title>Transmission and reflection properties of periodic dispersive materials</title> (1994)

The transfer matrix method has been used for the calculation of transmission and reflection properties of periodic and/or disordered dispersive photonic band gap (PBG) materials. We have studied the transmission properties of: (1) PBG materials constructed of low resistive Si wafers forming the newly proposed layer-by-layer structure and exhibiting PBG at around 100 GHz; (2) a two-dimensional square lattice consisting of metallic wires; (3) materials having structural gaps close to a polariton gap.
Continuous Flow Synthesis of Difluoroamine Systems by Direct Fluorination (2013)

Continuous flow methodology for the synthesis of perfluoroaryl difluoroamine derivatives by reaction of fluorine gas with an appropriate perfluoroaniline substrate is described, further demonstrating the efficient use of flow regimes for reactions involving highly reactive and toxic reagents.
Dual-polarized wireless communications: from propagation models to system performance evaluation (2008)

In this paper, we address the potential benefits of dual-polarized arrays in multi-antenna wireless systems. After an extensive literature overview of experimental data, we present a new and simple analytical framework to model dual-polarized Rayleigh and Ricean fading channels for arbitrary array sizes. The model relies on a limited number of physical parameters, such as the channel spatial correlations, the channel co-polar and the cross-polar ratios and the antenna cross-polar discrimination. Then, we investigate the multiplexing advantage of dual-polarized transmissions through the evaluation of the ergodic mutual information, for both TITO and MIMO systems. Finally, the performance of two space-time coding schemes (Alamouti OSTBC and uncoded spatial multiplexing) is evaluated via a detailed analysis of the pairwise error probability.
Gene-gene Interaction of AhR With and Within the Wnt Cascade Affects Susceptibility to Lung Cancer (2021)

Abstract Introduction: Aberrant Wnt signalling, regulating cell development and stemness, is observed in many cancer entities. Aryl hydrocarbon receptor ( AhR ) mediates tumorigenesis of environmental pollutants. Complex interaction patterns of genes assigned to AhR/Wnt -signalling were recently associated to lung cancer susceptibility. Aim: To assess the association and predictive ability of AhR/Wnt -genes with lung cancer in cases and controls of European descent. Methods: Odds ratios (OR) were estimated for genomic variants assigned to the genes DKK2 , DKK3 , DKK4 , FRZB , SFRP4 and Axin2 and other lung cancer-related genes. Logistic regression models with variable selection were trained, validated and tested to predict lung cancer. Further, decision trees were created to investigate variant x variant interaction. All analyses were performed for overall lung cancer and for subgroups. Results: No association with overall lung cancer was observed, but within the subgroups of ever smokers (e.g. maker rs2722278 SFRP4; OR=1.20; 95%-CI: 1.13-1.27; p=5.6 10 -10 ) and never smokers. Although predictability is poor, AhR/Wnt-variants are unexpected overrepresented in optimized prediction scores for overall lung cancer and for small cell lung cancer. Remarkable, the score for never-smokers contained solely two AhR/Wnt-variants . The optimal decision tree for never smokers consists of 7 AhR/Wnt-variants and only two lung cancer variants, no assigned to any CHRN gene. Conclusions: The role of variants belonging to Wnt / AhR- pathways in lung cancer susceptibility may be underrated in main-effects association analysis. Complex interaction patterns in individuals of European descent have moderate predictive capacity for lung cancer or subgroups thereof, especially in never smokers.
Optoelectronic oscillator using a LiNbO3 phase modulator for self-oscillating frequency comb generation (2006)

Optical frequency comb generation by using a novel optoelectronic oscillator (OEO) is proposed and demonstrated with the emphasis placed on self-oscillating operation. In the OEO, a wideband LiNbO3 phase modulator is driven with a large-amplitude radio-frequency (RF) feedback signal to generate a deeply phase-modulated light wave; accordingly, an optical frequency comb with a bandwidth greater than the RF signal is generated by self-oscillation. Although it generates multifrequency components, the OEO exhibits characteristics of a single-mode oscillator. Its operation is stable and self-starting. An optical frequency comb with a 120 GHz bandwidth and 9.95 GHz frequency spacing was successfully generated by self-oscillation at a single frequency.
Assembly of New Merocyanine Chromophores with a 1,8-Naphthalimide Core by a New Method for the Synthesis of the Methine Function (2015)

A new method for the synthesis of the monomethine group using nitro as a leaving group in an SN-Ar reaction is described. A series of novel merocyanine dyes has been synthesised and their photophysical properties have been elucidated. The longest wavelength absorption occurs in the range 519–619 nm and the molar absorptivities vary with the substituents and are in the range 1000–47700 L mol–1 cm–1. The dyes show high chemical and photostability. One example from the series has the ability to distinguish methanol from ethanol. The introduction of a quinoid fragment into the structure leads to a pronounced intramolecular charge transfer and hence a noticeable positive solvatochromism. The structures and electronic properties of the compounds have been studied by density functional theory (DFT) and time-dependent DFT.
Multipactor Coating for Sapphire RF Windows Using Remote Plasma-Assisted Deposition (2015)

Traditional application of multipactor coatings applied with sputtering techniques to high-power RF windows typically performs well when applied to sintered powder ceramics. Unfortunately, sputtered coatings do not adhere well to crystal materials, such as sapphire. This publication describes a plasma-assisted process that molecularly bonds the multipactor coating to the base window material. The performance was verified by measuring secondary electron emission yield and operating the window at high power. The coating process and performance are presented.
Analysis of energy saving in domestic ceramic industry kilns (2021)

Ceramic industrial kiln refers to the combustion equipment for ceramic production, which generally refers to roller kiln, shuttle tunnel kiln and shuttle kiln. Roller kiln refers to the kiln with continuous firing and rotating roller as the vehicle of the billet body; Tunnel kiln refers to the kiln which adopts continuous firing and takes rail kiln car as the transport vehicle of billet body. Shuttle kiln refers to the kiln which is fired intermittently and consists of kiln car, kiln chamber and kiln door. Factors influencing energy saving of kiln include construction materials, kiln structure, combustion technology, thermal insulation performance and automation control.
New perspectives on the annihilation electrogenerated chemiluminescence of mixed metal complexes in solution (2016)

Preliminary explorations of the annihilation electrogenerated chemiluminescence (ECL) of mixed metal complexes have revealed opportunities to enhance emission intensities and control the relative intensities from multiple luminophores through the applied potentials. However, the mechanisms of these systems are only poorly understood. Herein, we present a comprehensive characterisation of the annihilation ECL of mixtures of tris(2,2'-bipyridine)ruthenium(ii) hexafluorophosphate ([Ru(bpy)<sub>3</sub>](PF<sub>6</sub>)<sub>2</sub>) and <i>fac</i>-tris(2-phenylpyridine)iridium(iii) ([Ir(ppy)<sub>3</sub>]). This includes a detailed investigation of the change in emission intensity from each luminophore as a function of both the applied electrochemical potentials and the relative concentrations of the two complexes, and a direct comparison with two mixed (Ru/Ir) ECL systems for which emission from only the ruthenium-complex was previously reported. Concomitant emission from both luminophores was observed in all three systems, but only when: (1) the applied potentials were sufficient to generate the intermediates required to form the electronically excited state of both complexes; and (2) the concentration of the iridium complex (relative to the ruthenium complex) was sufficient to overcome quenching processes. Both enhancement and quenching of the ECL of the ruthenium complex was observed, depending on the experimental conditions. The observations were rationalised through several complementary mechanisms, including resonance energy transfer and various energetically favourable electron-transfer pathways.
3D numerical solutions inside the pyramid of textured silicon solar cells (2022)

This paper presents a fully-coupled 3D drift-diffusion simulation for the volume within the pyramids of a textured surface on a silicon wafer to compute the surface parameters needed for solar-cell modeling. First, the diffusion process is numerically simulated, resulting in a nonuniform surface dopant concentration that is higher at the pyramid's peak and ridges. Results are presented for quasi-Fermi potential, recombination, and hole current as a function of forward bias; lateral current flow in the diffused layer; and photogeneration profiles that account for double-bounce polarized reflection from the pyramid facets. Some surprising results include a bulbous protrusion of the space-charge region below the pyramid peak and majority-current crowding near the center of the pyramidal volume. The software used, PC3S, is open-source and freely available for personal computers running Microsoft Excel (Mac or Windows).