gebhart/patrepeval huggingface dataset:
Electric-Field-Effect Spin Switching with an Enhanced Number of Highly Polarized Electron and Photon Spins Using p-Doped Semiconductor Quantum Dots (2021)

Electric-field-effect spin switching with an enhanced number of highly polarized electron and photon spins has been demonstrated using p-doped semiconductor quantum dots (QDs). Remote p-doping in InGaAs QDs tunnel-coupled with an InGaAs quantum well (QW) significantly increased the circularly polarized, thus electron-spin-polarized, photoluminescence intensity, depending on the electric-field-induced electron spin injection from the QW as a spin reservoir into the QDs. The spin polarity and polarization degree during this spin injection can be controlled by the direction and the strength of the electric field, where the spin direction can be reversed by excess electron spin injection into the QDs via spin scattering at the QD excited states. We found that the maximum degrees of both parallel and antiparallel spin polarization to the initial spin direction in the QW can be enhanced by p-doping. The doped holes without spin polarization can effectively contribute to this electric-field-effect spin switching after the initial electron spin injection selectively removes the parallel hole spins. The optimized p-doping induces fast spin reversals at the QD excited states with a moderate electric-field application, resulting in an efficient electric-field-driven antiparallel spin injection into the QD ground state. Further excess hole doping prevents this efficient spin reversal due to multiple electron-hole spin scattering, in addition to a spin-state filling effect at the QD excited states, during the spin injection from the QW into the QDs.
A highly selective and sensitive electrochemical determination of melamine based on succinic acid functionalized copper oxide nanostructures (2015)

This study presents the development of a highly selective and sensitive electrochemical sensor for the determination of melamine from aqueous environments.
P‐212: Late‐News‐Poster: Study on the Ideal Structural Change of Perovskite LEDs for Enhanced Performances by Using Different Perovskite Composition (2020)

In this study, we compared the effects of two types of perovskite compositions on the efficiency of perovskite LED devices. The perovskite based on methylammonium cation (MA) requires interlayer for efficient device performances and formamidinium cation (FA) showed much better efficiency when we used simpler structure without using any interlayer. To understand those different optimal structure, we proceeded exciton lifetime measurement to confirm exciton quenching processes at the HIL and EML interface.
Organic Light‐Emitting Devices: High‐Performance Green OLEDs Using Thermally Activated Delayed Fluorescence with a Power Efficiency of over 100 lm W−1 (Adv. Mater. 13/2016) (2016)

On page 2638, H. Sasabe, J. Kido, and co-workers introduce a high-power-efficiency thermally activated fluorescent organic LED with 100 lm W−1, developed using energy transfer from an exciplex. The performance is almost comparable with that in a phosphorescent organic LED.
An innovative behavioral health care curriculum: The integrated advanced practice addictions nursing subspecialty. (2022)

Implementation of similar innovative curricula across health disciplines may significantly improve the care delivered to patients with problematic substance use in traditional medical settings. (PsycInfo Database Record (c) 2022 APA, all rights reserved).
Kinetic Analysis on the Photoluminescence Enhancement of 3-Mercaptopropyl Trimethoxysilane-Modified ZnS:Mn2+ Nanocrystal Colloidal Solution by Aging Effect (2005)

The ZnS:Mn 2+ nanocrystal colloidal solution is prepared by the in situ surface modification co-precipitation method in the presence of 3-mercaptopropyl trimethoxysilane (MPS). The increase in the fractional photoluminescence (PL) intensity by the aging of this solution is represented as a first-order reaction. Judging from the small activation energy, we conclude that Mn 2+ ions are exchanged with Zn 2+ ions at the surface of ZnS nanocrystals during aging to increase the PL intensity.
Patient Monitoring Across the Spectrum of Heart Failure Disease Management 10 Years After the CHAMPION Trial (2021)

Despite significant advances in drug-based and device-based therapies, heart failure remains a major and growing public health problem associated with substantial disability, frequent hospitalizations, and high economic costs. Keeping patients well and out of the hospital has become a major focus of heart failure disease management. Achieving and maintaining such stability in heart failure patients requires a holistic approach, which includes at least the management of the underlying heart disease, the management of comorbidities and the social and psychological aspects of the disease, and the management of haemodynamic/fluid status. In this regard, accurate assessment of elevated ventricular filling pressures or volume overload, that is, haemodynamic or pulmonary congestion, respectively, before the onset of worsening heart failure symptoms represents an important management strategy. Unfortunately, conventional methods for assessing congestion, such as physical examination and monitoring of symptoms and daily weights, are insensitive markers of worsening heart failure. Assessment tools that directly measure congestion, accurately and in absolute terms, provide more actionable information that enables the application of treatment algorithms designed to restore patient stability, in a variety of clinical settings. Two such assessment tools, implantable haemodynamic monitors and remote dielectric sensing (ReDS), meet the prerequisites for useful heart failure management tools, by providing accurate, absolute, and actionable measures of congestion, to guide patient management. This review focuses on the use of such technologies, across the spectrum of heart failure treatment settings. Clinical data are presented that support the broad use of pulmonary artery pressure-guided and/or ReDS-guided heart failure management in heart failure patients with reduced and preserved left ventricular ejection fraction.
Amplification of ribosomal RNA genes in acute myeloid leukemia (2001)

Gene amplification is a relatively rare event in acute myeloid leukemia (AML). Double minutes (dmin) and homogeneously staining regions are well established phenomena as cytogenetic correlates of gene amplification. Recently, however, two additional mechanisms leading to gene amplification, i.e., segmental jumping translocations and formation of ring chromosomes, have been described. We report four patients with AML, in whom bone marrow cells exhibited amplifications of ribosomal RNA (rRNA) genes in the form of ring chromosomes or a hsr. In two patients, the MLL gene, and in one patient the CBFA2 gene were shown to be co-amplified with rRNA genes. In two of the four patients, multiple copies of alpha-satellite sequences of the centromeres 13 and 21, respectively, were also demonstrated. In three of the four patients, the clinical course was very aggressive, leading to death within 2-8 months. In these three patients, complex karyotype abnormalities were found, whereas the karyotype of Patient 4 was characterized only by supernumerary ring 21 chromosomes of different sizes and a trisomy 8 in half of the metaphases. Modes of origin and clinical significance of the amplification of rRNA genes are discussed.
Generalized Faddeev-Popov Method for a Deformed Supersymmetric Yang-Mills Theory (2015)

In this paper, we will study the deformation of a three dimensional $\mathcal{N} = 2$ supersymmetry gauge theory. We will deform this theory by imposing non-anticommutativity. This will break the supersymmetry of the theory from $\mathcal{N} = 2$ supersymmetry to $\mathcal{N} = 1$ supersymmetry. We will address the problem that occurs in the Landau gauge due to the existence of multiple solutions to the gauge fixing condition. This will be done by generalizing the Faddeev-Popov method. This formalism is motivated from the Nicolai map in topological field theories. Finally, we will study the extended BRST symmetry that occurs in this theory.
Discovery ofXe109andTe105: SuperallowedαDecay near Doubly MagicSn100 (2006)

Two new alpha emitters 109Xe and 105Te were identified through the observation of the 109Xe --> 105Te --> 101Sn alpha-decay chain. The 109Xe nuclei were produced in the fusion-evaporation reaction 54Fe(58Ni,3n)109Xe and studied using the Recoil Mass Spectrometer at the Holifield Radioactive Ion Beam Facility. Two transitions at Ealpha = 4062 +/- 7 keV and Ealpha = 3918 +/- 9 keV were interpreted as the l = 2 and l = 0 transitions from the 7/2+ ground state in 109Xe (T1/2 = 13 +/- 2 ms) to the 5/2+ ground state and a 7/2+ excited state, located at 150 +/- 13 keV in 105Te. The observation of the subsequent decay of 105Te marks the discovery of the lightest known alpha-decaying nucleus. The measured transition energy Ealpha = 4703 +/- 5 keV and half-life T1/2 = 620 +/- 70 ns were used to determine the reduced alpha-decay width delta2. The ratio delta105Te(2)/delta213Po(2) of approximately 3 indicates a superallowed character of the alpha emission from 105Te.
Shape parameters of UGV delivery robots that affect subject's perception of safety (2022)

When developing new technologies, the safety of people is always important. Mostly, this is assured by safety standards that are also developed in the same direction as technologies. However, from a psychological perspective, it is also essential to investigate whether people feel safe under certain circumstances. The goal of this study was to find out what kind of appearance and shape parameters could affect the feeling of safety. It was evaluated 32 different designs of delivery UGV (unmanned ground vehicles) robots developed by different companies worldwide to conclude which shape factors have a positive or negative impact on perceived safety. This report presents some of the findings already identified in the study. The results show that for Brazilian subjects the robot's forward slant shape, backward slant shape, and roundness are shape factors that may influence on safety feeling. Additionally, nationality may play significant differences in the perception of safety towards the shape of a delivery UGV robot. Those findings are important to deepen the discussion in the effect of shape as a fundamental visual aspect on robot's design, and how far they can be related to the feeling of safety, which is primordial for a better acceptance of robots in social environment. Finally, further work is mentioned as a plan for the next steps of this study.
Exploring time-resolved photoluminescence for nanowires using a three-dimensional computational transient model (2018)

Time-resolved photoluminescence (TRPL) has been implemented experimentally to measure the carrier lifetime of semiconductors for decades. For the characterization of nanowires, the rich information embedded in TRPL curves has not been fully interpreted and meaningfully mapped to the respective material properties. This is because their three-dimensional (3-D) geometries result in more complicated mechanisms of carrier recombination than those in thin films and analytical solutions cannot be found for those nanostructures. In this work, we extend the intrinsic power of TRPL by developing a full 3-D transient model, which accounts for different material properties and drift-diffusion, to simulate TRPL curves for nanowires. To show the capability of the model, we perform TRPL measurements on a set of GaAs nanowire arrays grown on silicon substrates and then fit the measured data by tuning various material properties, including carrier mobility, Shockley-Read-Hall recombination lifetime, and surface recombination velocity at the GaAs-Si heterointerface. From the resultant TRPL simulations, we numerically identify the lifetime characteristics of those material properties. In addition, we computationally map the spatial and temporal electron distributions in nanowire segments and reveal the underlying carrier dynamics. We believe this study provides a theoretical foundation for interpretation of TRPL measurements to unveil the complex carrier recombination mechanisms in 3-D nanostructured materials.
Observation of strong red photoluminescence with broadband in indium oxynitride nanoparticles (2006)

Indium oxynitride nanoparticles were synthesized on a silicon substrate in nitrogen atmosphere using the method involving thermal evaporation of pure indium in a two-zone reactor. Nanoscale compositional analysis by energy dispersion spectrum showed the existence of indium oxynitride compound. X-ray diffraction analysis further confirmed high crystallization and nitrogen atom existence within the nanoparticles. Scanning electron microscopy investigations showed shape transformation from amorphous sphere to well-shaped octahedron with an average nanoparticle size ranging from 50nmto1μm when the growth temperature of the substrate was increased from 600to900°C. Photoluminescence study was performed on the indium oxynitride nanoparticle samples grown at different temperatures. It was found that with increasing growth temperatures there was not only the formation of high quality indium oxynitride nanoparticles but also an increase in the intensities of emissions. These nanoparticles grown at 900°C could emit a strong photoluminescence spectrum centered around 700nm with a broad full width at half maximum of about 250nm, spanning the whole red segment.
Immunohistochemical Study on Pancreatic Secretory Trypsin Inhibitor (PSTI) in Gastric Carcinomas (1990)

The expression of pancreatic secretory trypsin inhibitor (PSTI) was studied immunohistochemically in 106 cases of gastric carcinoma. Of the 45 intestinal-type carcinomas, 34 cases (76%) expressed PSTI: 15 (63%) of 24 early carcinomas and 19 (90%) of 21 advanced carcinomas, the incidence being significantly different (P less than 0.05). Furthermore, in the intestinal-type carcinomas, a significant correlation was observed between PSTI expression and clinical stage or nodal involvement. On the other hand, of the 61 diffuse-type carcinomas, including 27 early and 34 advanced carcinomas, 54 cases (89%) were positive for PSTI; a high incidence of the PSTI expression was observed in both early and advanced carcinomas, being 93% and 85%, respectively. Moreover, PSTI-positive cells were localized in more than half of the early diffuse-type gastric carcinomas at the invading zone of the surrounding tissues. The incidence of PSTI expression in advanced scirrhous-type carcinomas (100%) was significantly higher than that (76%) in medullary-type ones (P less than 0.05). Thus, the present findings, together with the previous reports that PSTI stimulates 3H-thymidine incorporation into DNA in human fibroblasts, suggest that the PSTI expressed in gastric carcinomas may possibly possess a biologic function responsible for the tumor growth and progression and for the stromal proliferation of fibrous tissues.
Country Program Evaluation: Honduras 2015-2018 (2019)

As part of its 2017-2018 annual work program, the Office of Evaluation and Oversight (OVE) has evaluated the Country Program with Honduras 2015-2018. This is OVE's fifth independent country program evaluation (CPE) of the IDB's program with Honduras and the first to cover the work of both the IDB and IDB Invest in that county. It covers the IDB Group's program during the 2015-2018 period, which was guided by the IDB Country Strategy with Honduras 2015-2018 (document GN-2796-1). The preceding evaluations covered the periods 1990-2000 (document RE-263), 2001-2006 (document RE-328), 2007-2010 (document RE-390), and 2011-2014 (document RE-469).
Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells (2008)

The protein kinase encoded by the Tpl2 protooncogene plays an obligatory role in the transduction of Toll-like receptor and death receptor signals in macrophages, B cells, mouse embryo fibroblasts, and epithelial cells in culture and promotes inflammatory responses in animals. To address its role in T cell activation, we crossed the T cell receptor (TCR) transgene 2C, which recognizes class I MHC presented peptides, into the Tpl2(-/-) genetic background. Surprisingly, the TCR2C(tg/tg)/Tpl2(-/-) mice developed T cell lymphomas with a latency of 4-6 months. The tumor cells were consistently TCR2C(+)CD8(+)CD4(-), suggesting that they were derived either from chronically stimulated mature T cells or from immature single positive (ISP) cells. Further studies showed that the population of CD8(+) ISP cells was not expanded in the thymus of TCR2C(tg/tg)/Tpl2(-/-) mice, making the latter hypothesis unlikely. Mature peripheral T cells of Tpl2(-/-) mice were defective in ERK activation and exhibited enhanced proliferation after TCR stimulation. The same cells were defective in the induction of CTLA4, a negative regulator of the T cell response, which is induced by TCR signals via ERK. These findings suggest that Tpl2 functions normally in a feedback loop that switches off the T cell response to TCR stimulation. As a result, Tpl2, a potent oncogene, functions as a tumor suppressor gene in chronically stimulated T cells.
A missense mutation inASRGL1is involved in causing autosomal recessive retinal degeneration (2016)

Inherited retinal dystrophies are a group of genetically heterogeneous conditions with broad phenotypic heterogeneity. We analyzed a large five-generation pedigree with early-onset recessive retinal degeneration to identify the causative mutation. Linkage analysis and homozygosity mapping combined with exome sequencing were carried out to map the disease locus and identify the p.G178R mutation in the asparaginase like-1 gene (ASRGL1), segregating with the retinal dystrophy phenotype in the study pedigree. ASRGL1 encodes an enzyme that catalyzes the hydrolysis of L-asparagine and isoaspartyl-peptides. Studies on the ASRGL1 expressed in Escherichia coli and transiently transfected mammalian cells indicated that the p.G178R mutation impairs the autocatalytic processing of this enzyme resulting in the loss of functional ASRGL1 and leaving the inactive precursor protein as a destabilized and aggregation-prone protein. A zebrafish model overexpressing the mutant hASRGL1 developed retinal abnormalities and loss of cone photoreceptors. Our studies suggest that the p.G178R mutation in ASRGL1 leads to photoreceptor degeneration resulting in progressive vision loss.
TNT Detection Using Multiplexed Liquid Array Displacement Immunoassays (2006)

The presence of trace contamination of soil and groundwater with explosives is an ongoing concern, for which improved methods are required to facilitate their detection and quantification. This is true both for the monitoring of remediation and for site characterization. Immunosensors have been found effective for solution-phase detection of environmental contaminants. Our work utilized the Luminex100 (flow cytometer) to detect TNT in a multiplexed displacement immunoassay format. The Luminex100 can perform a multiplexed assay by discriminating between up to 100 different bead sets. We used this capability to evaluate four different TNT monoclonal antibodies, two recombinant TNT antibodies, and a control antibody simultaneously for the rapid detection of TNT and other nitroaromatics. TNT could be detected at 0.1 ppb and quantified over the range of 1.0 ppb to 10 ppm. In addition, the assay was shown to be effective in various matrixes such as lake water, seawater, and acetone extracts of soil. Seawater required dilution with two parts buffer to avoid loss of microspheres, while the acetone extracts were diluted 100-fold or more to minimize solvent affects.
Inflammatory markers and the risk of Alzheimer disease (2007)

Higher spontaneous production of interleukin 1 or tumor necrosis factor alpha by peripheral blood mononuclear cells may be a marker of future risk of Alzheimer disease (AD) in older individuals. These data strengthen the evidence for a pathophysiologic role of inflammation in the development of clinical AD.
Spin-torque-induced oscillation at zero bias field in a magnetoresistive nanopillar with a free layer with first- and second-order uniaxial anisotropy (2015)

Spin-torque-induced magnetization dynamics in a nanopillar having a perpendicularly magnetized free layer with first- and second-order uniaxial anisotropy and an in-plane magnetized reference layer is studied theoretically on the basis of the macrospin model. It is shown that in the presence of second-order uniaxial anisotropy, self-oscillation is induced even at zero bias magnetic field. Analytical expressions for the threshold current, condition of the second-order anisotropy constant required for oscillation, and current dependence of the oscillation frequency are obtained.
Microscale NMR Screening of New Detergents for Membrane Protein Structural Biology (2008)

The rate limiting step in biophysical characterization of membrane proteins is often the availability of suitable amounts of protein material. It was therefore of interest to demonstrate that microcoil nuclear magnetic resonance (NMR) technology can be used to screen microscale quantities of membrane proteins for proper folding in samples destined for structural studies. Micoscale NMR was then used to screen a series of newly designed zwitterionic phosphocholine detergents for their ability to reconstitute membrane proteins, using the previously well characterized beta-barrel E. coli outer membrane protein OmpX as a test case. Fold screening was thus achieved with microgram amounts of uniformly (2)H, (15)N-labeld OmpX and affordable amounts of the detergents, and prescreening with SDS-gel electrophoresis ensured efficient selection of the targets for NMR studies. A systematic approach to optimize the phosphocholine motif for membrane protein refolding led to the identification of two new detergents, 138-Fos and 179-Fos, that yield 2D [ (15)N, (1)H]-TROSY correlation NMR spectra of natively folded reconstituted OmpX.
Critical Requirement for the Membrane-Proximal Cytosolic Tyrosine Residue for CD28-Mediated Costimulation In Vivo (2001)

The YMNM motif that exists in the CD28 cytoplasmic domain is known as a binding site for phosphatidylinositol 3-kinase and Grb-2 and is considered to be important for CD28-mediated costimulation. To address the role of the YMNM motif in CD28 cosignaling in primary T cells, we generated transgenic mice on a CD28 null background that express a CD28 mutant lacking binding ability to phosphatidylinositol 3-kinase and Grb-2. After anti-CD3 and anti-CD28 Ab stimulation in vitro, the initial proliferative response and IL-2 secretion in CD28 Y189F transgenic T cells were severely compromised, while later responses were intact. In contrast to anti-CD3 and anti-CD28 Ab stimulation, PMA and anti-CD28 Ab stimulation failed to induce IL-2 production from CD28 Y189F transgenic T cells at any time point. Using the graft-vs-host reaction system, we assessed the role of the YMNM motif for CD28-mediated costimulation in vivo and found that CD28 Y189F transgenic spleen cells failed to engraft and could not induce acute graft-vs-host reaction. Together, these results suggest that the membrane-proximal tyrosine of CD28 is required for costimulation in vivo. Furthermore, these results indicate that the results from in vitro assays of CD28-mediated costimulation may not always correlate with T cell activation in vivo.
Near-Histologic Resolution Images of Cervical Dysplasia Obtained With Gabor Domain Optical Coherence Microscopy (2021)

A GDOCM imaging system has the potential to obtain histologic resolution images of the cervix in the evaluation of squamous intraepithelial neoplasia. This pilot study allowed for optimizing the imaging system and paved the way for a future diagnostic accuracy study. The development of this technology could streamline the evaluation of patients at risk for cervical neoplasia.