gebhart/patrepeval huggingface dataset:
A promising class of luminescent derivatives of Silver(I) and Gold(I)‐N‐heterocyclic carbene (2020)

Abstract Starting from proligand 1‐methyl‐2‐(phenyl)imidazo[1,5‐a]pyridine‐2‐iumchloride ( 1 .HCl), 1‐methyl‐2‐(phenyl)imidazo[1,5‐a]pyridine silver(I)chloride, ( 2 ) has been prepared. Synthesis, structures and photophysical properties of (2,2 / −bipyridyl)‐1‐methyl‐2‐(phenyl)imidazo[1,5‐a]pyridinesilver(I)hexaflurophosphate, ( 3 ), 1‐methyl‐2‐(phenyl)imidazo[1,5‐a]pyridinesilver(I)carbazolate, ( 4 ) and 1‐methyl‐2‐(phenyl)imidazo[1,5‐a]pyridinegold(I)carbazolate, ( 5 ) are focused. Herein we have first reported the NHC‐Ag‐(bpy/carbazole). All the complexes have been characterized by elemental analysis, various spectroscopic studies and finally screened for luminescent properties. All the complexes are strongly emissive. Solid state structures of 2 , 3 , 4 and 5 have been determined by X‐ray diffraction studies. Conventionally, complex 2 adopts linear geometry whereas complex 3 embraces triangular planar geometry around Ag; complex 4 and 5 clinches linear geometry around Ag/Au. All the complexes absorb light within 275–343 nm. Complex 3 is luminous at ~407 mn, whereas complex 4 and 5 luminous at ~360 nm having short life time 1.00–6.97 ns. The quantum yield (Φ em ) of the complexes varies 0.106–0.186. It is expected variation of luminescence arises due to change of metal and the chromophore (bpy/carbazole). Density Functional Theory (DFT) and Temparature Dependent Density Functional Theory (TDDFT) calculations were performed to verify crystallographically derived parameters and to calculate the UV–Vis properties of the ground state as well as of the first excited state of the complexes.
Frontal Affinity Chromatography – Mass Spectrometry for Ligand Discovery and Characterization (2007)

This chapter contains sections titled: Introduction The Basic Frontal Method FAC – Basic Theory FAC Advantages FAC Disadvantages Enabling FAC with MS Detection Direct FAC-MS Methods for Compound Binding Data Direct Method for Discovering and Ranking Multiple Ligands Indirect Methods System Advancements – Fluidics, Immobilization, Detection Column System Breakthrough Curve Detection and Data Analysis Select Applications Summary and Evaluation
Zeolita modicada y procedimiento de obtención de la zeolita modificada. (2000)

Referencia OEPM: P9500268.-- Fecha de solicitud: 09/02/1995.-- Titulares: Universidad Politécnica de Valencia (UPV), Consejo Superior de Investigaciones Científicas (CSIC).
Photonic Crystal Enhanced Microscopy: Multimode Imaging for Photonic Crystal Biosensors (2011)

We introduce a photonic crystal enhanced microscope (PCEM) (Figure 1a) as an imaging approach that combines enhanced fluorescence (EF) and label-free (LF) imaging modalities for assays performed upon a photonic crystal (PC) surface (Figure 1b). The instrument utilizes a collimated laser illumination source and tuning of the incidence angle to enable highly efficient coupling to PC optical resonances. The system has been used for label-free imaging of DNA and protein capture spots for microarray quality control, while amplifying signals from fluorescent-tagged hybridized biomolecules by &gt;500× compared to performing the same assay on an ordinary glass surface. The same system has also been used for imaging cell surface attachment to the PC, and measuring how drugs modulate cell attachment.
Dynamic Cross-domain Link Creation for Interconnection of Heterogeneous Knowledge Bases (2008)

This paper presents a method for the creation of dynamic cross-domain links for interconnection of heterogeneous knowledge bases. The proposed method represents various relationships in heterogeneous fields and navigates to related contents in these heterogeneous fields. Most information resources are connected by static links that do not describe the significance of the connections. Recently, it has been important for a lot of users to employ search engines not only for retrieving Web pages but also for understanding or learning semantic concepts. However, in the current Web environment, it remains difficult for a user to understand the relationships among arbitrary concept. The proposed method dynamically creates links between heterogeneous fields depending on the user context. The method obtains various related information resources between heterogeneous fields while understanding various relationships among arbitrary concepts. Our approach has functions for the reconfiguration of Web resources and legacy knowledge bases by dynamic links creation.
Privacy preserving decentralized power system state estimation with phasor measurement units (2016)

This paper presents a privacy preserving approach to decentralized state estimation in multi-area power systems. By formulating state estimation as a model-distributed regularized least-squares (MDRLS) problem, we ensure that the state variables and system matrix of each area are hidden from all other areas in order to protect privacy and sensitive information. We present a scheme that solves the primal MDRLS problem using the alternating direction method of multipliers, and a second method that solves the dual problem using a distributed form of the coordinate descent algorithm. Only information related to current measurements on tie-lines linking neighboring areas is exchanged between those areas. The proposed schemes enable the local state estimator in each area to estimate the voltage magnitude and phase angle of each bus in its own control area from phasor measurement units (PMU) without the need for full local PMU-observability. The novelty of the proposed methods is in that they employ the inherently hierarchical architecture of the wide-area monitoring system to perform decentralized state estimation. Our simulation results show that the estimation error of both methods converges to that of the centralized approach.
Enhanced Adaptive Mode Decision of H.264 Based on Efficient AZCB Prediction (2007)

This paper proposes an enhanced adaptive mode decision scheme for fast H.264 encoders. By efficiently predicting AZCB (All Zero Coefficient Block), the proposed scheme can encode motion pictures in H.264 up to 2.86 and 1.68 times faster than JM9.3 and AMD [1], respectively. Besides, this scheme significantly reduces the encoding performance fluctuation of AMD across tested bit-rates and video sequences.
Mid-Infrared Microphotonics Using Air-clad Silicon Pedestal Structures (2013)

Towards Mid-Infrared silicon microphotonic circuits, we demonstrate broadband on-chip silicon structures including straight, bent waveguides, and beam splitters, utilizing a novel air-clad pedestal configuration. Transmission loss of 2.7 dB/cm is obtained at λ=3.7 um.
LOS estimation in overlapped multipath WCDMA scenarios via adaptive threshold (2003)

Mobile positioning is a topic of high interest in current mobile communication systems. The position location is usually derived from the estimates of the distances between mobile and the base stations, which are obtained from the time-of-arrival of the line-of-sight (LOS) component. In time-varying multipath fading channels, the LOS component is not always present, and even when it is present, it might be obstructed by one or several components arriving within short delay (i.e., shorter than the width of the main lobe of the pulse shaping function). This situation of overlapped paths is one of the main sources of error in LOS estimation. We introduce here an adaptive threshold for estimating the LOS component in the presence of overlapped multipath components for wideband CDMA (WCDMA) positioning applications. Our threshold technique is used in conjunction with Teager-Kaiser (TK) based delay estimation. The TK estimator was previously introduced in the context of RAKE receiver and it was shown to be an efficient method for solving closely spaced multipaths.
Micrometer-Sized Suction Cup Array with Strong Adhesion to Wet Surface (2019)

This paper presents a flexible adhesive pad which is covered with a dense array of micro suction cup array whose base diameter and height are 100 μm and ~30 μm, respectively. We show that the adhesion of the fabricated micro suction cup array dramatically increases when the surface is wet. The maximum adhesion force per unit area of the proposed suction cup array to a wet smooth surface is approximately 0.37 MPa, which is more than 3 times higher than the theoretical limit of a passive suction cup. Moreover, the adhesion strength is independent of the surface wettability of the substrate and surface tension of the lubricated liquid. Finally, we show that the micro suction cup array can also adhere to curve surfaces with radius curvature as small as 10 mm, with an adhesion strength of approximately 0.12 MPa in wet condition.
Supplementary Figure 2 from Capivasertib, an AKT Kinase Inhibitor, as Monotherapy or in Combination with Fulvestrant in Patients with <i>AKT1</i><sup>E17K</sup>-Mutant, ER-Positive Metastatic Breast Cancer (2023)

&lt;p&gt;Supplementary Figure 2. PFS Association With {greater than or equal to}50% Decrease from Baseline in AKT1E17K at Cycle 2 Day 1 in ctDNA&lt;/p&gt;
Computer Aided Optimisation of the Thermal Management During Laser Beam Melting Process (2014)

The quality of a part produced by laser beam melting strongly depends on the melting process in particular on the melt pool shape stability. The geometry of the generated part influences the ability of the local heat dissipation and therefore affects the constancy of the melt pool shape. The presented study is focused on the numerical analysis of the temperature distribution in the vicinity of the melt pool during laser beam melting process depending on the local geometry of the part. After the discussion of the numerical and experimental setups a prediction of the improved process parameters towards stable melting process are introduced. The developed numerical analysis shows a great efficiency for the optimisation of the thermal management during laser beam melting.
ONVMS applied to a new advanced portable EMI system data (2012)

The ortho-normalized volume magnetic source (ONVMS) technique is applied to a new time domain EMI instrument called portable decoupled electromagnetic induction sensor (PEDEMIS); The system provides multiple deployment options (carted or carried); multimode operation (detection, interrogation, deep detection, wide interrogation); multi static data that is collected with flexible, decoupled and detachable sensors with precise positioning. In this paper we first describe the geometries of the PEDEMIS transmitters and receivers, then present the procedures to model the way they establish primary fields and measure subsurface responses, and, finally, illustrate the comparisons between modeled and actual data.
Extremely small differential non-linearity in a DMOS capacitor based cyclic ADC for CMOS image sensors (2014)

This letter reports an extremely small differential non-linearity (DNL) in a cyclic analog-to-digital converter (ADC) using depletion-mode MOS (DMOS) capacitors for CMOS image sensors (CISs). Compared with conventional 1.5b digital-to-analog converter (DAC) configuration using 3 reference signals, the cyclic ADC with split sampling DMOS capacitors in the 1.5b DAC has the maximum DNL of +0.125/−0.125 LSB at 14b despite the large applied voltage dependency of the DMOS capacitors of 2.47%.
O2–03–05: Early detection of Alzheimer's disease‐linked aβ peptide accumulation in the lens by non‐invasive quasi‐elastic light scattering (2007)

AD is characterized by excessive accumulation of β-amyloid (Aβ) in the brain that begins years before the onset of cognitive symptoms. Presymptomatic detection of the underlying disease process will accelerate clinical efficacy testing and facilitate early therapeutic intervention when emerging treatments are expected to be most effective and enduring. We previously identified Aβ, AD-linked amyloid pathology, and co-localizing supranuclear cataracts (SNC) in the lenses of patients with AD (Goldstein et al., Lancet, 2003). Here, we developed and tested low-energy infrared laser quasi-elastic light scattering (QLS) technology for early quantitative detection and monitoring of AD-linked amyloid lens pathology in vivo. Non-invasive infrared QLS, slit lamp stereophotomicroscopy, quantitative western blot, fluoro-ELISA, immunogold EM, tryptic digest MS sequencing. In vivo, QLS was able to discriminate non-anesthetized Tg mice with clear lenses from age-matched non-anesthetized wild-type controls by 10 months of age before β-amyloid pathology was detectable in the brain. We sequenced human Αβ in Tg2576 mouse lens and demonstrated human Aβ generation from AD-linked variant human amyloid precursor protein. Human Aβ accumulated in the cytoplasm of Tg lens fiber cells as electron-dense microaggregates that scatter light. Human Aβ promoted aggregation of mouse lens protein and corresponding QLS signal changes in vitro that replicated the QLS changes detected in Tg mice in vivo. Our data support AD-linked Aβ aggregation in the lens as an optically accessible early AD biomarker and highlight the potential of non-invasive QLS for AD screening, diagnosis, and monitoring.
Spatial Molecular Architecture of the Microbial Community of a Peltigera Lichen (2016)

Microbes are commonly studied as individual species, but they exist as mixed assemblages in nature. At present, we know very little about the spatial organization of the molecules, including natural products that are produced within these microbial networks. Lichens represent a particularly specialized type of symbiotic microbial assemblage in which the component microorganisms exist together. These composite microbial assemblages are typically comprised of several types of microorganisms representing phylogenetically diverse life forms, including fungi, photosymbionts, bacteria, and other microbes. Here, we employed matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) imaging mass spectrometry to characterize the distributions of small molecules within a <i>Peltigera</i> lichen. In order to probe how small molecules are organized and localized within the microbial consortium, analytes were annotated and assigned to their respective producer microorganisms using mass spectrometry-based molecular networking and metagenome sequencing. The spatial analysis of the molecules not only reveals an ordered layering of molecules within the lichen but also supports the compartmentalization of unique functions attributed to various layers. These functions include chemical defense (e.g., antibiotics), light-harvesting functions associated with the cyanobacterial outer layer (e.g., chlorophyll), energy transfer (e.g., sugars) surrounding the sun-exposed cyanobacterial layer, and carbohydrates that may serve a structural or storage function and are observed with higher intensities in the non-sun-exposed areas (e.g., complex carbohydrates). <b>IMPORTANCE</b> Microbial communities have evolved over centuries to live symbiotically. The direct visualization of such communities at the chemical and functional level presents a challenge. Overcoming this challenge may allow one to visualize the spatial distributions of specific molecules involved in symbiosis and to define their functional roles in shaping the community structure. In this study, we examined the diversity of microbial genes and taxa and the presence of biosynthetic gene clusters by metagenomic sequencing and the compartmentalization of organic chemical components within a lichen using mass spectrometry. This approach allowed the identification of chemically distinct sections within this composite organism. Using our multipronged approach, various fungal natural products, not previously reported from lichens, were identified and two different fungal layers were visualized at the chemical level.
Unsupervised morpheme segmentation and morphology induction from text corpora using Morfessor 1.0 (2005)

In this work, we describe the first public version of the Morfessor software, which is a program that takes as input a corpus of unannotated text and produces a segmentation of the word forms observed in the text. The segmentation obtained often resembles a linguistic morpheme segmentation. Morfessor is not language-dependent. The number of segments per word is not restricted to two or three as in some other existing morphology learning models. The current version of the software essentially implements two morpheme segmentation models presented earlier by us (Creutz and Lagus, 2002; Creutz, 2003). The document contains user’s instructions, as well as the mathematical formulation of the model and a description of the search algorithm used. Additionally, a few experiments on Finnish and English text corpora are reported in order to give the user some ideas of how to apply the program to his own data sets and how to evaluate the results. 1
Fluorinated Amphiphilic Polymers and Their Blends for Fouling-Release Applications: The Benefits of a Triblock Copolymer Surface (2011)

Surface active triblock copolymers (SABC) with mixed polyethylene glycol (PEG) and two different semifluorinated alcohol side chains, one longer than the other, were blended with a soft thermoplastic elastomer (TPE), polystyrene-block-poly(ethylene-ran-butylene)-block-polystyrene (SEBS). The surface composition of these blends was probed by X-ray photoelectron spectroscopy (XPS) and near edge X-ray absorption fine structure (NEXAFS) spectroscopy. The surface reconstruction of the coatings in water was monitored qualitatively by dynamic water contact angles in air as well as air bubble contact angle measurements in water. By blending the SABC with SEBS, we minimize the amount of the SABC used while achieving a surface that is not greatly different in composition from the pure SABC. The 15 wt % blends of the SABC with long fluoroalkyl side chains showed a composition close to that of the pure SABC while the SABC with shorter perfluoroakyl side chains did not. These differences in surface composition were reflected in the fouling-release performance of the blends for the algae, Ulva and Navicula.
High Voltage Staircase Drive Circuit for Triggered High-Intensity Focused Ultrasound Treatment (2012)

In triggered high-intensity focused ultrasound (HIFU) treatment, cavitation clouds are produced by extremely high intensity trigger pulses and enhance the effect of following heating waves. The ultrasound intensity must be quickly changed from that for trigger pulses to that for heating waves before cavitation clouds vanish. We newly designed and constructed a class D amplifier based on a staircase voltage drive concept, which has the capability of outputting high voltage waves for trigger pulses and continuous waves for heating waves and the capability of fast switching between the two modes. Its efficacy was confirmed by an experiment with a BSA containing polyacrylamide gel.
Quality assessment of clinical trial registration with traditional Chinese medicine in WHO registries (2019)

The registration quality of TCM CTs should be improved by prospective registration, full completion of WHO TRDS, full reporting of TCM information and results sharing. Further full set of trial registration items for TCM trials should be developed thus to standardise the content of TCM trial registration.
Synthesis of 4‐Arylethynyl‐2‐methyloxazole Derivatives as mGluR5 Antagonists for Use in the Treatment of Drug Abuse. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Model-based and Data-driven Approaches for Downlink Massive MIMO Channel Estimation (2021)

We study downlink channel estimation in a multi-cell Massive multiple-input multiple-output (MIMO) system operating in time-division duplex. The users must know their effective channel gains to decode their received downlink data. Previous works have used the mean value as the estimate, motivated by channel hardening. However, this is associated with a performance loss in non-isotropic scattering environments. We propose two novel estimation methods that can be applied without downlink pilots. The first method is model-based and asymptotic arguments are utilized to identify a connection between the effective channel gain and the average received power during a coherence interval. The second method is data-driven and trains a neural network to identify a mapping between the available information and the effective channel gain. Both methods can be utilized for any channel distribution and precoding. For the model-aided method, we derive all expressions in closed form for the case when maximum ratio or zero-forcing precoding is used. We compare the proposed methods with the state-of-the-art using the normalized mean-squared error and spectral efficiency (SE). The results suggest that the two proposed methods provide better SE than the state-of-the-art when there is a low level of channel hardening, while the performance difference is relatively small with the uncorrelated channel model.
Thermal denitration of high concentration nitrate salts waste water (2003)

This study investigated the thermodynamic and the thermal decomposition properties of high concentration nitrate salts waste water for the lagoon sludge treatment. The thermodynamic property was carried out by COACH and GEMINI II based on the composition of nitrate salts waste water. The thermal decomposition property was carried out by TG-DTA and XRD. Ammonium nitrate and sodium nitrate were decomposed at 250 .deg. C and 730 . deg. C, respectively. Sodium nitrate could be decomposed at 450 .deg. C in the case of adding alumina for converting unstable Na{sub 2}O into stable Na{sub 2}O.Al{sub 2}O{sub 3}. The flow sheet for nitrate salts waste water treatment was proposed based on the these properties data. These will be used by the basic data of the process simulation.
Hepatic steatosis and metabolic risk factors among patients with chronic hepatitis B: The multicentre, prospective CAP‐Asia study (2023)

We aimed to compare the severity of liver disease, metabolic profile and cardiovascular disease (CVD) risk of chronic hepatitis B (CHB) patients with and without hepatic steatosis and patients with non-alcoholic fatty liver disease (NAFLD). Patients with NAFLD and CHB were prospectively enrolled from 10 Asian centres. Fibroscan was performed for all patients and hepatic steatosis was defined based on controlled attenuation parameter >248 dB/m. CVD risk was assessed using the Framingham risk score. The data for 1080 patients were analysed (67% NAFLD, 33% CHB). A high proportion (59%) of CHB patients had hepatic steatosis. There was a significant stepwise increase in alanine aminotransferase, aspartate aminotransferase, gamma-glutamyl transpeptidase, controlled attenuation parameter and liver stiffness measurement, from CHB patients without hepatic steatosis to CHB patients with hepatic steatosis to NAFLD patients (p < 0.001 for all comparisons). There was a significant stepwise increase in the proportion of patients with metabolic syndrome and in CVD risk, with very high or extreme CVD risk seen in 20%, 48% and 61%, across the groups (p < 0.001 between CHB patients with and without hepatic steatosis and p < 0.05 between CHB patients with hepatic steatosis and NAFLD patients). In conclusion, there was a high proportion of CHB patients with hepatic steatosis, which should be diagnosed, as they may have more severe liver disease, so that this and their metabolic risk factors can be assessed and managed accordingly for a better long-term outcome.
Ultrafast Measurement of Femtosecond Time-bin Qubits Using Optimized Up-conversion Single Photon Detector (2022)

We developed and optimized the up-conversion single photon detector with the temporal resolution of 415 fs. Consequently, we successfully evaluated single-photon level pseudo time-bin qubits with their pulse interval of only 800 fs.