gebhart/patrepeval huggingface dataset:
A Testbed for Experimenting 5G-V2X Requiring Ultra Reliability and Low-Latency (2017)

The 5G ultra reliable and low-latency communication (uRLLC) will become a significant enhancement to the future assisted driving and fully autonomous driving. For experimenting various uRLLC-enabled cooperative driving applications, we have designed a Vehicle-to-everything (V2X) testbed based on the software defined radio (SDR), which features flexible reconfiguration in short frame structure and numerology, fast real-time processing, flexible synchronization and easy to deploy. The usecases and communication requirements for future cooperative autonomous driving are discussed to motivate the system design and technical enablers that can achieve the most stringent linklevel communication requirements of cooperative autonomous driving. The main building blocks of the testbed include a reconfigurable RF front-end and optimized base-band processing on general purposed CPUs. The technical enablers include a new OFDM-like waveform based on Pulse-shaping, a flexible and self-contained frame-structure design, GNSS-aided hybrid synchronization and low-latency scheduled multiple-access. We finally present some experimental results from lab measurements and field trial.
Soluble CD14 acts as a negative regulator of human T cell activation and function (1999)

T cell activation is controlled by the coordination of stimulatory and negative regulatory signals which are not completely defined. In this study we tested for a possible direct effect of CD14 on the regulation of T cell activation and function. We show that soluble CD14 (sCD14) induces inhibition of antigen-mediated peripheral blood mononuclear cells (PBMC) proliferation and anti-CD3-mediated proliferation of CD4+CD8−, CD4−CD8+ and CD4+CD8+ T cell clones. This effect is not due to cell death, but results from a marked inhibition of IL-2 production. Proliferation of T cell clones due to exogenous IL-2 is not affected by sCD14. We also found that sCD14 inhibits production of another Th1-like cytokine, IFN-γ and a Th2-like cytokine, IL-4. Importantly, sCD14 induces a progressive accumulation of the inhibitory protein IκB-α. We show that sCD14 binds to activated T cells. Following cell activation, biotinylated sCD14 stains CD3+ PBMC, as well as human T cell clones with varying intensity. The binding is saturable, can be inhibited by excess of unlabeled sCD14 and, following binding, sCD14 is internalized. Collectively, these findings reveal a previously unrecognized function of sCD14, namely its capacity to negatively regulate T lymphocyte activation and function by interacting directly with activated T cells.
ChemInform Abstract: Bisubstrate Reaction Templates. Examination of the Consequences of Identical versus Different Binding Sites. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Personal exposure to environmental tobacco smoke in workplace and away from work settings: A 16 city case study (1995)

A large study of personal exposure of non-smokers to environmental tobacco smoke (ETS) has been conducted in 16 cities in the United States. Individual participants wear two personal sampling pumps, one each at work and away-from-work. Samples of breathing zone air are collected, and subsequently analyzed for both particle phase and gas phase markers of ETS, including respirable suspended particulate matter (RSP), UV-absorbing and fluorescing particulate matter, solanesol, nicotine, 3-ethenyl pyridine, and myosmine. In addition, prior- and post-exposure saliva samples are collected, in order that smoking status may be determined using salivary cotinine. Participants are segregated into a 2{times}2 factorial study design: smoking and non-smoking homes and workplaces. A comparison of the demographic distribution of the sample population with that of the United States indicates that the sample population is more female and of higher socioeconomic status. The data indicates that median 8-hour or 16-hour exposure levels are considerably lower than those which would be extrapolated from short duration area measurements. Median exposure levels of nicotine, 3-ethenyl pyridine, and RSP were 0.034, 0.029, and 23 {mu}g/m{sup 3} respectively in non-smoking workplaces, vs. 0.21, 0.16, and 23 {mu}g/m{sup 3} in workplaces where smoking was observed. Median 16-hour exposure levels for these same components away from work where subjects observed tobacco products in use were 0.36, 0.25, and 23 {mu}g/m{sup 3}, compared with 0.024, 0.019, and 15 {mu}g/m{sup 3} when no tobacco products were observed.
Replicated plastic optical components for optical micro systems (2002)

Our approach for passively aligned and low loss coupling of fiber-to-fiber, fiber array-to-array, or lasers/detectors to (single-mode) fibers is schematically shown. A silicon or polymeric platform with built-in alignment features, such as V-groves, alignment posts or rails, is used for the placement of fibers (or fiber ribbons). Replicated plastic optical components such as diffractive optical elements (DOEs) are used for imaging and inserted into the platform. Specific to the solution is the fabrication of the imaging components as replicated plastic elements with built-in mechanical alignment structures to fit into the complementary features of the micro-optical bench.
Dystrophin Delivery in Dystrophin-Deficient DMD mdx Skeletal Muscle by Isogenic Muscle-Derived Stem Cell Transplantation (2003)

Duchenne's muscular dystrophy (DMD) is a lethal muscle disease caused by a lack of dystrophin expression at the sarcolemma of muscle fibers. We investigated retroviral vector delivery of dystrophin in dystrophin-deficient DMD(mdx) (hereafter referred to as mdx) mice via an ex vivo approach using mdx muscle-derived stem cells (MDSCs). We generated a retrovirus carrying a functional human mini-dystrophin (RetroDys3999) and used it to stably transduce mdx MDSCs obtained by the preplate technique (MD3999). These MD3999 cells expressed dystrophin and continued to express stem cell markers, including CD34 and Sca-1. MD3999 cells injected into mdx mouse skeletal muscle were able to deliver dystrophin. Though a relatively low number of dystrophin-positive myofibers was generated within the gastrocnemius muscle, these fibers persisted for up to 24 weeks postinjection. The injection of cells from additional MDSC/Dys3999 clones into mdx skeletal muscle resulted in varying numbers of dystrophin-positive myofibers, suggesting a differential regenerating capacity among the clones. At 2 and 4 weeks postinjection, the infiltration of CD4- and CD8-positive lymphocytes and a variety of cytokines was detected within the injected site. These data suggest that the transplantation of retrovirally transduced mdx MDSCs can enable persistent dystrophin restoration in mdx skeletal muscle; however, the differential regenerating capacity observed among the MDSC/Dys3999 clones and the postinjection immune response are potential challenges facing this technology.
A Novel, Domino Synthesis of Tricyclic Benzimidazole Derivatives Using Continuous Flow (2019)

A novel method for synthesis of tricyclic benzimidazole derivatives by using continuous flow reactor is reported. Disadvantages of the well-known batch methods have been avoided utilizing the flow chemistry technology. Beside the one pot reductive cyclization using H-Cube Pro®, the dehydration step was also optimized producing the desired lactam compounds. Then the acylation was optimized under microwave conditions and that reaction was also integrated into the flow system using an Asia heater module. This acylation dramatically reduced the reaction time under continuous-flow conditions, with a residence time of 30 min.
Boosted energy-storage efficiency by controlling conduction loss of multilayered polymeric capacitors (2020)

Among the organic dielectrics, polyvinylidene fluoride PVDF-based polymers present the highest level of polarizability with permittivity >35. Nonetheless, their applications in advanced electronics and industrial uses are limited by significant leakage current under high voltage, which is considered the principal cause of device energy consumption and short lifetime. Therefore, the main objective of this paper was to focus on alternative capacitor structure-based polyvinylidene fluoride-trifluoroethylene-chlorotrifluoroethylene (PVDF-TrFE-CTFE) terpolymers to efficiently limit the leakage current and lead to enhanced electrical breakdown with negligible degradation of polarization level. The novel bilayer capacitor was constructed by depositing a thin barrier layer of high polar PVDF-HFP copolymer on the terpolymer via a rapid solution-casting technique. The relationship between leakage current, dielectric strength and conduction mechanisms was investigated. Implementation of such a barrier layer led to a significant reduction (70%) in leakage current and ferroelectric losses (approximately 90%), thus boosting the performance of multilayered material up to 50% of enhanced energy-storage efficiency. Experimental results are very promising, allowing to confirm that combining both terpolymer and copolymer in a hybrid multilayer design makes a possibility to achieve the best compromise in terms of energy efficiency, dielectric properties, and breakdown strength.
Single-FPGA, scalable, low-power, and high-quality 3D ultrasound beamformer (2016)

We present an efficient FPGA architecture suitable for a medical 3D ultrasound beamformer. We tackle the delay calculation bottleneck, which is the heart and the most critical part of the beamformer, by proposing a computationally efficient design that is able to perform volumetric real-time beamforming on a single-chip FPGA. The design has been demonstrated for a 32×32-channel receive probe, and we extrapolated the requirements of the architecture for 80×80 channels.
Gas-Particle Partitioning of Formaldehyde in Mainstream Cigarette Smoke (2020)

Summary A diffusion denuder apparatus has been used to investigate the gas-particle partitioning of formaldehyde, acetaldehyde, acrolein and crotonaldehyde in cigarette mainstream smoke (MS), compounds that are of interest owing to their toxicity and near quantitative retention in the body during cigarette smoking. Formaldehyde showed the best performance in denuder experiments with simple aldehyde-air mixtures owing to the relatively fast rate of the heterogeneous reaction formaldehyde(g) + dinitrophenylhydrazine(s) → hydrazone(s). Analysis with the G ormley -K ennedy equation revealed that formaldehyde denuder removal approached, but did not attain, complete efficiency even under optimized operational conditions. Acetaldehyde, acrolein and crotonaldehyde were trapped with considerably lower efficiency than formaldehyde under the denuder conditions used, and more effective denuder wall coatings would be required to examine gas-particle partitioning of these other carbonyls. The proportion of formaldehyde in the smoke particulate phase initially entering the denuder was &gt; 99%, but loss of formaldehyde from the smoke particles was relatively rapid leading to 35%–61% deposition over the denuder length. The temperature dependence of formaldehyde deposition in the denuder was well predicted using Henry's law constant for aqueous formaldehyde solutions. These observed properties of formaldehyde are primarily due to reversible reactions of formaldehyde with water in cigarette smoke leading to the much less volatile species methanediol, its oligomers and hydrate. These data suggest that cigarette smoke inhalation is likely to expose the deeper-lung generations of smokers to greater relative formaldehyde exposure, and greater genotoxic risk at those generations than might occur through inhalation of formaldehyde vapour alone. Risk assessments of formaldehyde in cigarette smoke should be updated to recognise this modified risk profile.
Abstract 232: Targeting HER3 mRNA by a locked nucleic antisense molecule enhances the antitumor activity of gefitinib in vivo (2011)

Abstract Background: The HER family consists of four tyrosine kinase receptors designated as EGFR, HER2, HER3 and HER4. HER3 is a unique member that plays a critical role in tumor growth since it 1) can heterodimerize with EGFR or HER2 and is the main link to the downstream PI3K/Akt signaling axis, 2) can mediate resistance to HER1/2-targeted therapeutics, and 3) unlike EGFR or HER2, is not typically overexpressed but still hyperphosphorylated in a variety of tumors. Resistance to the EGFR-tyrosine kinase inhibitors, such as gefitinib, can be associated with EGFR mutations and/or activation of HER3 ultimately leading to activation of the PI3K/AKT axis. We have used an RNA antagonist of HER3, designated EZN-3920, to explore the ability of this compound to inhibit tumor growth and overcome resistance to HER1/2 therapeutics. Methods: Tissue culture cells were treated with EZN-3920, a locked nucleic acid (LNA)-based oligonucleotide complementary to HER3. Compound was either added to tissue culture media (i.e. no transfection) in vitro or prepared in saline and given IV in vivo. Endpoints were measured by qRT-PCR, MTT, Western Blot analysis, Immunohistochemistry, and tumor size. Results: EZN-3920 down modulated HER3 mRNA, protein expression, PI3K/AKT signaling, and inhibited tumor cell proliferation. In vivo, systemic administration of EZN-3920, prepared in saline, resulted in specific down- modulation of HER3 mRNA and protein expression, as well as blockade in PI3K/AKT signaling pathways in NSCLC HCC827 associated with tumor growth inhibition. Similar results were also shown in tumor derived from BT-474-M1 breast carcinoma xenograft models. Interestingly, in the HCC827 tumor model, EZN-3920 at 30 mg/kg (biweekly for 4 weeks, i.v.) and gefitinib at 15 mg/kg (5 times a week for two weeks) completely shrank established tumors while either treatment alone only delayed tumor growth by 40-60%. Conclusions: The studies suggest that down regulation of HER3 by antisense molecule EZN-3920 inhibits human tumor growth in mice. Beyond this, antitumor effects of gefitinib can be enhanced by HER3 down modulation in gefitinib-sensitive tumors. On-going studies will determine if tumors that are resistant to HER1/2 therapeutics will either have enhanced sensitivity to EZN-3920 and/or the compound can restore sensitivity to such agents. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 232. doi:10.1158/1538-7445.AM2011-232
Viral infection of human progenitor and liver-derived cells encapsulated in three-dimensional PEG-based hydrogel (2008)

We have studied the encapsulation of human progenitor cells into 3D PEG hydrogels. Replication-incompetent lentivirus promoter reporter vectors were found to efficiently detect the in vivo expression of human hepatic genes in hydrogel-encapsulated liver progenitor cells. Similarly, hydrogel-encapsulated cells could be efficiently infected with hepatitis C virus, and progeny infectious virus could be recovered from the media supernatants of the hydrogels. Provocatively, the diameters of these virus particles range from approximately 50 to 100 nm, while the calculated mesh size of the 8 k hydrogel is 44.6 +/- 1.7 A. To reconcile how viral particles can penetrate the hydrogels to infect the encapsulated cells, we propose that microfractures/defects of the hydrogel result in a functional pore size of up to 20 fold greater than predicted by theoretical mesh calculations. These results suggest a new model of hydrogel structure, and have exciting implications for tissue engineering and hepatitis virus studies.
Perceptual considerations for the design and display of stereoscopic imagery (2010)

Stereoscopic displays afford more accurate 3D percepts than conventional displays due to the added depth cue of disparity. However, 3D shape and scene layout are often misperceived when viewing stereoscopic displays. For example, viewing from the wrong distance alters an object’s perceived size and shape. It is crucial to understand the causes of such misperceptions so one can determine the best approaches for minimizing them. We develop the mathematics of an existing geometric model for calculating misperceptions, and then describe common viewing situations in which the model fails to make a prediction. We show how the visual system’s interpretation of vertical disparities can supplement the existing model and help predict the percepts associated with improper viewing of stereoscopic displays.
We also discuss blur as a previously under-appreciated depth cue present in both stereo and non-stereo images. We present a probabilistic model that explains how the pattern of blur in an image together with relative depth cues indicates the apparent scale of the image’s contents. To examine the correspondence between the model/algorithm and actual viewer experience, we conducted an experiment with human viewers and compared their estimates of absolute distance to the model’s predictions. We did this for images with geometrically correct blur due to defocus and for images with commonly used approximations to the correct blur. The agreement between the experimental data and model predictions was excellent. A semi-automated algorithm is included, which helps one apply the correct pattern of blur to change the apparent size of a scene. The algorithm and model allow one to manipulate blur precisely and to achieve the desired perceived scale efficiently.
Finally, we discuss the utility of stereoscopic displays for medical imaging. The technology’s greatest benefits arise in applications in which monocular cues are uninformative. Its specific strengths and shortcomings are presented in terms of diagnostics, education, surgical planning, minimally invasive surgery, and telesurgery. General guidelines and common errors are also listed to help potential users avoid unwanted misperceptions and visual fatigue.
Direct Synthesis of H2O2 from H2 and O2 over Gold, Palladium, and Gold–Palladium Catalysts Supported on Acid‐Pretreated TiO2 (2009)

Palladium-ringed gold: The acid-pretreated Au–Pd catalysts supported on TiO2 have a well-defined gold-rich core (blue) and palladium-rich shell (green). This type of core and shell enhances the catalytic activity of the catalyst for the direct synthesis of H2O2 from H2 and O2. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Intrazeolite metallocenes: chemistry, spectroscopy, and dynamics (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIntrazeolite metallocenes: chemistry, spectroscopy, and dynamicsGeoffrey A. Ozin and John GodberCite this: J. Phys. Chem. 1989, 93, 2, 878–893Publication Date (Print):January 1, 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://pubs.acs.org/doi/10.1021/j100339a066https://doi.org/10.1021/j100339a066research-articleACS PublicationsRequest reuse permissionsArticle Views231Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Towards a real time sensor for focusing through scattering media (2012)

Materials such as milk, paper, white paint and biological tissue scatter light. As a result, transmitted light intensity through these materials is a speckle pattern, having often a short persistence time. Recently, advances in optics to control light through disordered media have reported an increasing efficiency. Consequently, that allows us to foresee a real time sensor that achieve such task in an integrated way. Thereby, in this perspective, we propose a genetic algorithm implemented with pyramidal approach in a CMOS image sensor, which matches integrated data processing and short persistence time. Our algorithm have been simulated with a faithful model. Results show at least a gain of a factor 10 compared to the state of the art algorithms.
The synthesis of bis(propynoyloxy) aromatics (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleThe synthesis of bis(propynoyloxy) aromaticsJon R. Wehler and William A. FeldCite this: J. Chem. Eng. Data 1989, 34, 1, 142–143Publication Date (Print):January 1, 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://pubs.acs.org/doi/10.1021/je00055a041https://doi.org/10.1021/je00055a041research-articleACS PublicationsRequest reuse permissionsArticle Views1162Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Schizophrenia connectivity investigation by DTI Tractography (2006)

Multiple lines of evidence suggest that schizophrenia is associated with abnormalities in neural circuitry and impaired structural connectivity. Although largely investigated by imaging studies, very few results have been published on in-vivo image-based connectivity investigations, and those published report often contradictory findings. In this study, we propose to conduct a group study to evaluate the differences in structural connectivity between schizophrenic patients and control subjects using Diffusion MRI. The proposed methodology is based on Tractography, a technique inferring the main neural fiber tracks from Diffusion MRI data. We study mainly the thalamo-frontal fiber-tracts, supposed to be involved in schizophrenia.
Conception d’antenne pour lecteur RFID UHF champ proche intégrableaux vêtements (2014)

International audience
Erosive External Otitis (2010)

We propose that EEO, which occurs in the absence of immune suppression or diabetes, is a clinical entity that is distinct from the more commonly diagnosed malignant external otitis and that the management of EEO is primarily surgical debridement with skin grafting.