gebhart/patrepeval huggingface dataset:
Chemistry of the Coccoidea. VI. Pigments of the lac insect Austrotachardia acaciae (Hemiptera): Chemistry and crystal structure (1978)

Pigments of the Australian lacciferid, Austrotachardia acaciae Maskell, differ from those of Indian lac insects in that the major constituent is xantholaccaic acid B (9) rather than a mixture of laccaic acids. Its structure has been determined by single-crystal X-ray diffraction of a new hexamethyl derivative. Xantholaccaic acids have not previously been found in nature.
Editorial Commentary (2020)

No AccessUrology PracticePatient Care1 Jul 2020Editorial CommentaryThis article comments on the following:Urology in the Era of COVID-19: Mass Casualty Triage Arthur L. Burnett Arthur L. BurnettArthur L. Burnett The Johns Hopkins School of Medicine, Baltimore, Maryland More articles by this author View All Author Informationhttps://doi.org/10.1097/UPJ.0000000000000152.01AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Editorial Commentary." Urology Practice, 7(4), p. 271 © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsRelated articlesUrology PracticeApr 6, 2020, 12:00:00 AMUrology in the Era of COVID-19: Mass Casualty Triage Volume 7Issue 4July 2020Page: 271-271 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Arthur L. Burnett The Johns Hopkins School of Medicine, Baltimore, Maryland More articles by this author Expand All Advertisement PDF DownloadLoading ...
PERCUTANEOUS RADIO FREQUENCY ABLATION FOR HEMATURIA (2001)

No AccessJournal of UrologyCLINICAL UROLOGY: Case Reports1 Dec 2001PERCUTANEOUS RADIO FREQUENCY ABLATION FOR HEMATURIA BRADFORD J. WOOD, JAMES GRIPPO, and CHRISTIAN P. PAVLOVICH BRADFORD J. WOODBRADFORD J. WOOD , JAMES GRIPPOJAMES GRIPPO , and CHRISTIAN P. PAVLOVICHCHRISTIAN P. PAVLOVICH View All Author Informationhttps://doi.org/10.1016/S0022-5347(05)65560-7AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "PERCUTANEOUS RADIO FREQUENCY ABLATION FOR HEMATURIA." The Journal of Urology, 166(6), pp. 2303–2304 References 1 : The role of arterial embolization in renal cell carcinoma. Scand J Urol Nephrol1999; 33: 162. Google Scholar 2 : Radiofrequency ablation of renal cell carcinoma: early clinical experience. Radiology2000; 217: 665. Google Scholar 3 : Combined embolization and percutaneous radiofrequency ablation of a solid renal tumor. AJR Am J Roentgenol2000; 174: 1592. Google Scholar From the Special Procedures-Diagnostic Radiology Department, Clinical Center, National Cancer Institute, Urologic Oncology Branch, National Institutes of Health, Bethesda, Maryland© 2001 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 166Issue 6December 2001Page: 2303-2304 Advertisement Copyright & Permissions© 2001 by American Urological Association, Inc.Keywordsablationtherapeutic embolizationhematuriarenal cell carcinomaradiofrequency ablationMetricsAuthor Information BRADFORD J. WOOD More articles by this author JAMES GRIPPO More articles by this author CHRISTIAN P. PAVLOVICH More articles by this author Expand All Advertisement PDF downloadLoading ...
Autologous pericardial patch harvesting site for cardiac valve repair: anatomic and morphometric considerations. (1998)

Pericardium taken from the right anterior aspect of the pericardial sac in patients without cardiomegaly is the most appropriate tissue for valve reconstructive surgery, due to its thin nature and hence better fixation properties.
Ultraviolet light-emitting diodes at 340 nm using quaternary AlInGaN multiple quantum wells (2001)

An ultraviolet light-emitting diode with peak emission wavelength at 340 nm is reported. The active layers of the device were comprised of quaternary AlInGaN/AlInGaN multiple quantum wells, which were deposited over sapphire substrates using a pulsed atomic-layer epitaxy process that allows precise control of the composition and thickness. A comparative study of devices over sapphire and SiC substrates was done to determine the influence of the epilayer design on the performance parameters and the role of substrate absorption.
Frequency Offset Estimation for MB-OFDM-Based UWB Systems in Time-Variant Channels (2007)

We address low-complexity, highly-accurate frequency offset estimation for MB-OFDM-based UWB systems in time-variant channels. We present a simple channel model capturing an abrupt channel change characteristic of UWB systems. We devise an abrupt channel change detector and develop an oscillator frequency offset estimator based on best linear unbiased estimation principle while taking into account the time-variant channel behavior as well as the MB-OFDM characteristics such as different carrier frequency offsets, different channel responses, different channel energies, and different preamble structures in different frequency bands. If compared to the conventional estimators using correlation, our proposed method achieves significantly better estimation performance for all preamble patterns of the MB-OFDM system.
CHIROLUM- Comment limiter les impacts écologiques de l’éclairage artificiel nocturne le long des ILTe ? Influence des paramètres lumineuxdes LEDs sur les mouvements des chiroptères (2019)

National audience
A Characteristic Mode Based Decoupling Approach (2019)

A novel and compact decoupling structure has been introduced in this work to improve the mutual coupling of a two element microstrip antenna array. A systematic blending of electric and magnetic dipoles lead to the construction of the isolating element whose working principle has been explained using the theory of characteristic modes.
Environment as a Witness: Selective Proliferation of Information and Emergence of Objectivity (2004)

We study the role of the information deposited in the environment of an open quantum system in course of the decoherence process. Redundant spreading of information -- the fact that some observables of the system can be independently ``read-off'' from many distinct fragments of the environment -- is investigated as the essence of effective objectivity, the key ingredient of ``classical reality''. This focus on the environment as a communication channel underscores importance of quantum Darwinism -- selective proliferation of information about ``the fittest states'' chosen by the dynamics at the expense of their superposition -- as redundancy implies emergence of a unique preferred observable of the system. We demonstrate that the only observable that can leave such multiple imprints in its environment is the familiar pointer observable singled out by einselection for its predictability. Many independent observers monitoring the environment will therefore agree on the properties of the system as they can only learn about the preferred observable: in this operational sense, the selective spreading of information leads to the emergence of an objective "classical reality" from within quantum substrate.
A comprehensive model for sub-10 nm electron-beam patterning through the short-time and cold development (2017)

In this study, we propose a set of single-spot experiment to construct a comprehensive model of electron-beam lithography to describe the relation among the incident electrons, resist, and the development conditions such as durations and temperatures. Through the experiments, small feature can be achieved by performing a short-time development due to the high acceleration voltage and large depth of focus of electron-beam system. The singular point in the beginning of the development is also observed in our model and supported by the experimental data. In addition, we verify the characteristic region of each incident spot induced by the point spread function of the electron-beam system. We further fabricate the single line with narrow groove width by utilizing the results from single-spot experiment at low developing temperatures. The line is formed by arranging a series of incident points with a distance close to the characteristic radius. This method can eliminate the proximity effect effectively and thus the groove width is scaled down to 8 nm. By adopting the successful experience in the single line formation, dense array with narrow linewidth is also demonstrated under well suppression of the proximity effect. The minimum groove width of 9 nm with 30 nm pitch is achieved with 5 s development time at -10 °C. Finally, the exceptional capability of pattern transfer is presented due to the high aspect ratio of the resist.
A biomechanical test model for evaluating osseous and osteochondral tissue adhesives (2019)

Despite the challenges associated with biomechanical testing in small rodent models the preclinical ex-vivo test model presented herein is both sensitive and accurate. It enabled differences in tissue adhesive strength to be quantified even for very small osseous fragments (<Ø4mm). Importantly, this model can easily be scaled to larger animals and adapted to fracture fragment fixation in human bone. The present model is also compatible with other long-term in vivo evaluation methods (i.e. in vivo imaging, histological analysis, etc.).
Human iPSC-derived hypertrophic chondrocytes reveal a mutation-specific unfolded protein response in chondrodysplasias (2020)

Summary Chondrodysplasias are hereditary diseases caused by mutations in the components of growth cartilage. Although the unfolded protein response (UPR) has been identified as a key disease mechanism in mouse models, no suitable in vitro system has been reported to analyze the pathology in humans. Here, utilizing human chondrodysplasia-specific iPSCs, we examined the UPR caused by mutations in MATN3 or COL10A1 . In growth plate-like structures formed from iPSC-derived sclerotome in vivo , the hypertrophic zone was disrupted, and induced hypertrophic chondrocytes in vitro showed varying levels of ER stress depending on the mutation. Autophagy inducers and chemical chaperones succeeded in reducing ER stress only in some mutants, while transcriptome analysis revealed many mutation-specific changes in genes involved in apoptosis, metabolism, and protein trafficking. In this way, our system has allowed the precise evaluation of the UPR caused by each mutation, opening up new avenues for treatment of individual chondrodysplasia patients.
Effects of Selective Exclusion of Patients on Preterm Birth Test Performance (2020)

McElrath, Thomas F. MD, PhD; Cantonwine, David PhD, MPH; Stevenson, David K. MD; Shaw, Gary M. DrPH; Aghaeepour, Nima PhD; Quake, Stephen PhD Author Information
A novel design method for ultrabroadband chirped mirrors (1997)

For various applications in nonlinear optics and strong field-matter interactions pulses as short and intense as possible are required. The prerequisites of a short pulse duration are a broad spectrum and a chirp-free spectral phase (i.e. group delay dispersion, &lt;GDD&gt;=0). Recently, very efficient methods for spectral broadening have been developed, enabling the generation of a continuum stretching from the visible to the near infrared (500-950nm). This huge spectral width corresponds to a pulse duration of less than 3fs under the assumption of a bandwidth-limited pulse (GDD=0). In order to approach this limit, the positive GDD introduced by the spectral broadening mechanism and the beam manipulation has to be compensated. For high peak powers this compensation must be introduced by reflecting optical components that provide both high reflectance and the prescribed dispersion over the broadest possible bandwidth. This is one of the challenging problems solved by the chirped mirror design algorithm we present here. The mirrors we have produced exhibit high reflectance and constant negative dispersion over the bandwidth 600-950nm (the broadest ever demonstrated, to our knowledge), and have been capable of supporting the generation pulses as short as 4fs [1].
Telomerase contributes to tumorigenesis by a telomere length-independent mechanism (2002)

Once immortalized, human cells are susceptible to transformation by introduction of an oncogene such as ras. Several lines of evidence now suggest that the maintenance of telomere length is a major determinant of replicative lifespan in human cells and thus of the immortalized state. The majority of human tumor cells acquire immortality through expression of the catalytic subunit of telomerase (hTERT), whereas others activate an alternative mechanism of telomere maintenance (ALT) that does not depend on the actions of telomerase. We have examined whether ALT could substitute for telomerase in the processes of transformation in vitro and tumorigenesis in vivo. Expression of oncogenic H-Ras in the immortal ALT cell line GM847 did not result in their transformation. However, subsequent ectopic expression of hTERT in these cells imparted a tumorigenic phenotype. Indeed, this outcome was also observed after introduction of a mutant hTERT that retained catalytic activity but was incapable of maintaining telomere length. These studies indicate that hTERT confers an additional function that is required for tumorigenesis but does not depend on its ability to maintain telomeres.
A Novel Treatment of Opioid Cravings With an Effect Size of .73 for Unilateral Transcranial Photobiomodulation Over Sham (2020)

Unilateral t-PBM to the hemisphere with a more positive hemispheric emotional valence was an effective and safe treatment for opioid cravings as well as for depression and anxiety. Our results also lend support to the underlying premises of DBP.
A complete, multi-level conformational clustering of antibody complementarity-determining regions. (2014)

Classification of antibody Complementarity-Determining Region (CDR) conformations is an important step that drives antibody modelling and engineering, prediction from sequence, directed mutagenesis and induced-fit studies, and allows inferences on sequence-to-structure relations. Most of the previous work performed conformational clustering on a reduced set of structures or after application of various structure pre-filtering criteria. In this study, it was judged that a clustering of every available CDR conformation would produce a complete and redundant repertoire, increase the number of sequence examples and allow better decisions on structure validity in the future. In order to cope with the potential increase in data noise, a first-level statistical clustering was performed using structure superposition Root-Mean-Square Deviation (RMSD) as a distance-criterion, coupled with second- and third-level clustering that employed Ramachandran regions for a deeper qualitative classification. The classification of a total of 12712 CDR conformations is thus presented, along with rich annotation and cluster descriptions, and the results are compared to previous major studies. The present repertoire has procured an improved image of our current CDR Knowledge-Base, with a novel nesting of conformational sensitivity and specificity that can serve as a systematic framework for improved prediction from sequence as well as a number of future studies that would aid in knowledge-based antibody engineering such as humanisation.
Radiologic sinus inflammation and symptoms of chronic rhinosinusitis in a population‐based sample (2019)

In a general population-based sample in Pennsylvania, sinus opacification was more common among men than in women and opacification occurred in different locations by sex. Male sex, migraine headache, and prior sinus surgery were associated with higher odds of CRS<sub>S+O</sub> .
Improving web server performance by a clustering-based dynamic load balancing algorithm (2004)

A load balancing scheme is presented which allows HTTP requests to be dynamically migrated between clustered back-end Web servers based on the loading condition of the system. We adopt a nearest neighborhood clustering algorithm whereby an adaptive number of requests are migrated as determined by the real-time distribution of load among the servers. Experiment results demonstrate that our proposed algorithm yields the best performance when compared with several other common approaches.
Implementing a complex FIR filter on a novel parallel DSP architecture (2013)

The current paper describes a novel high-parallel architecture of a DSP (Digital Signal Processing) core and depicts optimizing techniques for implementation using the affiliated compiler. A demonstrative benchmark is presented for a FIR (Finite Impulse Response) complex filter, emphasizing differences over known digital signal processors.
Investigation on the use of deep eutectic solvent with microwave assistance for the extraction of ferulic acid from palm pressed fibre (2021)

Ferulic acid is a highly sought-after compound as functional food and nutraceuticals due to its antioxidative, anti-microbial and anti-inflammatory properties. Extraction of ferulic acid from oil palm pressed fibre by using microwave assisted deep eutectic solvent (DES) extraction was studied and reported. The influence of water content in the DES, microwave irradiation temperature and duration on the extraction efficiency were investigated. The viscosity of the DES of ChCl-AA, reduced from 9.678 ​mm2/s to 5.7356 ​mm2/s as the water content in the DES increased from 0% to 10% (v/v). DES with 30% (v/v) water (viscosity 2.547 ​mm2/s) was found to be optimal for ferulic acid extraction. The amount of ferulic acid extracted under microwave heating at 60 ​°C for 9 ​min were 0.609 ​mg/g – 0.617 ​mg/g and up to 1.123 ​mg/g when heated for 15 ​min. Response surface method showed that the microwave assisted DES extraction of ferulic acid from palm pressed fibre depended on the microwave temperature, heating duration and the interaction between the heating temperature and duration.
A movement and tremor identification algorithm for evaluations during deep brain stimulation (2022)

Ethical approval: The research related to human use complies with all the relevant national regulations, institutional policies and was performed in accordance with the tenets of the Helsinki Declaration and has been approved by the authors’ institutional review board or equivalent committee.
Bone extracellular matrix hydrogel enhances osteogenic differentiation of C2C12 myoblasts and mouse primary calvarial cells (2017)

Hydrogel scaffolds derived from the extracellular matrix (ECM) of mammalian tissues have been successfully used to promote tissue repair in vitro and in vivo. The objective of this study was to evaluate the osteogenic potential of ECM hydrogels prepared from demineralized and decellularized bovine bone in the presence and absence of osteogenic medium. Culture of C2C12 and mouse primary calvarial cells (mPCs) on decellularized bone ECM (bECM) and demineralized bone matrix (DBM) gels resulted in increased expression of osteogenic gene markers, including a 3.6- and 13.4-fold increase in osteopontin and 15.7- and 27.1-fold increase in osteocalcin when mPCs were cultured upon bECM with basal and osteogenic media, respectively. bECM hydrogels stimulated the osteogenic differentiation of C2C12 and mPCs even in the absence of osteogenic medium. These results suggest that bECM hydrogel scaffolds may have great utility in future clinical applications for bone tissue engineering. © 2017 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 106B: 900-908, 2018.
SOIL PARTICLE SIZE BY TIME-WEIGHT ACCUMULATIONS OF SEDIMENTATION (1965)

AN INVESTIGATION WAS CONDUCTED AT SOUTH DAKOTA UNIVERSITY OF THE METHOD FOR MEASURING THE AMOUNT OF MATERIAL THAT SETTLES OUT OF A SUSPENSION IN VARIOUS TIME INTERVALS. THE TESTS FOR SOILS PARTICLE SIZE BY SEDIMENTATION ARE BASED ON STOKES LAW FOR THE VELOCITY OF FALLING PARTICLES. WEIGHING EQUIPMENT DEVELOPMENTS AIDED IN THE MORE ACCURATE DETERMINATION OF THE TIME-WEIGHT ACCUMULATIONS OF SEDI- MENTATION. CURVES WERE PREPARED FOR THE DETERMINATION OF PARTICLE SIZE FROM FREE-FALL TIME. GRADATION CURVES MAY BE FOUND BY DETERMINING TIME INTERVALS OF SEDIMENTATION FOR VARIOUS PERCENTAGES OF THE TOTAL SAMPLE.
Human-in-the-Loop Optimization of Exoskeleton Assistance Via Online Simulation of Metabolic Cost (2022)

Many assistive robotic devices have been developed to augment or assist human locomotion. Despite advancements in design and control algorithms, this task remains challenging. Human walking strategies are unique and complex, and assistance strategies based on the dynamics of unassisted locomotion typically offer only modest reductions to the metabolic cost of walking. Recently, human-in-the-loop (HIL) methodologies have been used to identify subject-specific assistive strategies, which offer significant improvements to energy savings. However, current implementations suffer from long measurement times, necessitating the use of low-dimensional control parameterizations, and possibly requiring multiday collection protocols to avoid subject fatigue. We present a HIL methodology, which optimizes the assistive torques provided by a powered hip exoskeleton. Using musculoskeletal modeling, we are able to evaluate simulated metabolic rate online. We applied our methodology to identify assistive torque profiles for seven subjects walking on a treadmill, and found greater reductions to metabolic cost when compared to generic or off-the-shelf controllers. In a secondary investigation, we directly compare simulated and measured metabolic rate for three subjects experiencing a range of assistance levels. The time investment required to identify assistance strategies via our protocol is significantly lower when compared to existing protocols relying on calorimetry. In the future, frameworks such as these could be used to enable shorter HIL protocols or exploit more complex control parameterizations for greater energy savings.
Pipelining for dual supply voltages (2016)

Power is one of the most important metrics in the modern integrated circuit design. We optimize the circuit power using a dual-supply voltage (dual-V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">dd</sub> ) approach. In order to achieve an improved power efficiency, we have applied a new type of pipelining to reduce the number of gates need to be assigned to the high supply voltage given a target delay. Compared to the standard pipelining and the standard dual-V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">dd</sub> assignment, our design achieves the best of the two approaches without compromising any performance. Our overall design is tested on a set of standard ISCAS-85 benchmark circuits using an industrial cell library. Significant power savings (Avg. 10.4%) under a specified target delay are observed.