gebhart/patrepeval huggingface dataset:
Angiographic Embolization Of Renal Stab Wounds (1992)

Nonoperative management of renal stab wounds following complete radiographic assessment has become an accepted if not preferred therapeutic option. Selected injuries, however, including renal artery branch injuries, often require surgical intervention and result in partial or total nephrectomy. We report our experience with 16 renal branch arterial injuries secondary to street stabbing during the last 10 years that were managed with angiography and embolization techniques. Angiography with embolization was the initial treatment in 11 patients, while 5 had undergone emergency surgical intervention initially because of hemodynamic instability. Subsequently, gross hematuria recurred in the latter 5 patients and they were managed angiographically. Overall, 14 of 16 patients had prompt hemostasis documented either on the post-embolization angiogram or by clinical assessment. In 2 patients bleeding was increased but partial nephrectomy ultimately was required. Complications included nontarget embolization in 2 patients: 1 subsequently had hypertension and 1 had no untoward effect as a result of this complication. We conclude that angiography with transcatheter embolization techniques provides a safe and effective means of managing renal artery branch injuries secondary to stab wounds.
Simple routes to supramolecular squares with ligand corners:1:1 AgI:pyrimidine cationic tetranuclear assemblies (1998)

Simple, tetranuclear cationic supramolecular squares with ligands at the corners can be constructed using the geometry of the pyrimidine ligand and the directional tendencies of AgI coordination; the 1:1 AgI:pyrimidine squares have an open channel structure which facilitates selective ion exchange of pertechnetate over nitrate.
Proposal for a definition of CDVS engine APIs (2014)

108th MPEG meeting, Valencia, ES - April 2014 - ISO/IEC JTC 1/SC 29/WG 11 N14310
Cell cycle activity during seed priming is not essential for germination advancement in tomato (1999)

Seed priming is a technique of controlled hydration and drying that results in more rapid germination when the seeds are reimbibed. Advancement of radicle meristem cells into the S and G2 phases of the cell cycle, increasing the percentage of nuclei having a 4C DNA content, has been reported to occur during priming. It has been suggested that the efficiency of priming is related to the accumulation of 4C nuclei in the radicle meristem, but the extent of cell cycle activity varied among different treatments and seed lots. A wide range of priming treatments across temperatures, water potentials and durations can be compared on a common basis using the hydrothermal priming time model. Flow cytometry was used to monitor cell cycle activity in a number of tomato (Lycopersicon esculentum Mill.) seed lots during priming in relation to the accumulation of hydrothermal priming time and the subsequent germination rate response. In some seed lots, the percentage of 4C nuclei in the radicle meristems prior to emergence increased in proportion to accumulated hydrothermal priming time, while in other lots, no increase in nuclear DNA content was detected. All lots, however, demonstrated rapid radicle emergence following priming. Thus, replicative DNA synthesis in radicle meristem nuclei often occurred during seed priming, but an increase in the percentage of 4C nuclei was not essential for germination advancement.
Model-aided coding: a new approach to incorporate facial animation into motion-compensated video coding (2000)

We show that traditional waveform coding and 3-D model-based coding are not competing alternatives, but should be combined to support and complement each other. Both approaches are combined such that the generality of waveform coding and the efficiency of 3-D model-based coding are available where needed. The combination is achieved by providing the block-based video coder with a second reference frame for prediction, which is synthesized by the model-based coder. The model-based coder uses a parameterized 3-D head model, specifying the shape and color of a person. We therefore restrict our investigations to typical videotelephony scenarios that show head-and-shoulder scenes. Motion and deformation of the 3-D head model constitute facial expressions which are represented by facial animation parameters (FAPs) based on the MPEG-4 standard. An intensity gradient-based approach that exploits the 3-D model information is used to estimate the FAPs, as well as illumination parameters, that describe changes of the brightness in the scene. Model failures and objects that are not known at the decoder are handled by standard block-based motion-compensated prediction, which is not restricted to a special scene content, but results in lower coding efficiency. A Lagrangian approach is employed to determine the most efficient prediction for each block from either the synthesized model frame or the previous decoded frame. Experiments on five video sequences show that bit rate savings of about 35% are achieved at equal average peak signal-to-noise ratio (PSNR) when comparing the model-aided codec to TMN-10, the state-of-the-art test model of the M.263 standard. This corresponds to a gain of 2-3 dB in PSNR when encoding at the same average bit rate.
CpG island methylation patterns in patients with chronic lymphocytic leukemia (2007)

International audience
Oscillating steady states (2006)

The signal formation and properties of steady-state free precession (SSFP) in combination with alternating RF pulse phases or alternating spin precession is analyzed. Simulations and experiments demonstrate that the amplitudes of SSFP echo paths are significantly influenced by application of alternating phases either via the exciting RF pulse or via some external mechanism producing alternating spin precession. The influence of alternating phases on echo amplitudes is different for different echo paths. The primary SSFP echo paths F(0) (-) and F(0) (+) exhibit a signal reduction whereas higher-order echoes F(-1) (-) and F(1) (+) show a signal increase upon application of oscillating phases. This behavior can be described using a simple perturbation theory applied to the frequency response profile of balanced SSFP combined with a final signal integration over one balanced SSFP band. The high sensitivity of SSFP echo amplitudes to alternating RF pulse phases or precession is exemplarily used to detect and visualize propagating transverse acoustic shear waves. Detection of flow or alternating currents are further possibilities to apply this unique feature of SSFP.
A Model to Assess the Cost–Effectiveness of Pharmacogenomics Tests in Chronic Heart Failure: The Case of Ivabradine (2016)

Pharmacogenomics (PGx) tests have the potential of improving the effectiveness of expensive new drugs by predicting the likelihood, for a particular patient, to respond to a treatment. The objective of this study was to develop a pharmacoeconomic model to determine the characteristics and the cost-effectiveness of a hypothetical PGx test, which would identify patients who are most likely to respond to an expensive treatment for chronic heart failure. For this purpose, we chose the example of ivabradine. Our results suggest that the use of a PGx test that could select a subgroup of patients to be treated with an expensive drug has the potential to provide more efficient drug utilization.
Structure-Reactivity Correlations in the Reactions of Hydrocarbons on Transition Metal Surfaces. 1. Ring Contraction of Cyclooctene, 1,3-Cyclooctadiene, 1,5-Cyclooctadiene, and Cyclooctatetraene to Benzene on a Platinum(111) Surface (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure-Reactivity Correlations in the Reactions of Hydrocarbons on Transition Metal Surfaces. 1. Ring Contraction of Cyclooctene, 1,3-Cyclooctadiene, 1,5-Cyclooctadiene, and Cyclooctatetraene to Benzene on a Platinum(111) SurfaceMichael J. Hostetler, Ralph G. Nuzzo, Gregory S. Girolami, and Lawrence H. DuboisCite this: J. Phys. Chem. 1994, 98, 11, 2952–2962Publication Date (Print):March 1, 1994Publication History Published online1 May 2002Published inissue 1 March 1994https://pubs.acs.org/doi/10.1021/j100062a036https://doi.org/10.1021/j100062a036research-articleACS PublicationsRequest reuse permissionsArticle Views192Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
An Authentication Client Proxy mechanism for resource-constrained devices (2012)

The recent growth of Smart Grid and energy services introduced resource-constrained Internet communications devices such as smart meters, consumer electric devices, sensors, lighting devices and so on. In this paper, we propose a new proxy scheme designed for authentication and key establishment protocols for authenticating resource-constrained end-devices. The proposed scheme leverages key hierarchy in a way that the end-device can delegate the main protocol tasks of authentication and key establishment to the proxy and only a cryptographic and key management module including the root key of the key hierarchy needs to be retained by the end-device. The proposed scheme can reduce 70% and 28% of persistent storage for Class 1 and Class 2 memory-constrained devices, respectively. Also, the total memory reduction effect in the system consisting of a single proxy and multiple end-devices increases as the number of end-devices connected to one proxy increases.
A robot suit with hardware-based safety devices: Frequency response analysis of a velocity-based safety device (2015)

Safety is one of the most important issues in rehabilitation robot suits. We have designed a rehabilitation robot suit equipped with two mechanical safety devices called the “velocity-based safety device” and the “torque-based safety device”. The robot suit assists a patient's knee joint. The safety devices work even when the robot suit's computer breaks down, because they consist of only passive mechanical components without actuators, controllers, or batteries. The torque-based safety device stops the robot suit if it detects an unexpected high joint torque. Similarly, the velocity-based safety device stops the robot suit if it detects an unexpected high joint angular velocity. However, the mechanism for detecting the unexpected angular velocity in the velocity-based safety device may resonate with a walking cycle, because the mechanism has a bar, a rotary damper, and two tension springs, that is, the mechanism is a mass-spring-damper system. In this paper, we firstly review the robot suit equipped with the safety devices. Secondly, we analyze the mechanism for detecting the unexpected angular velocity and examine whether the mechanism resonates with a walking cycle. Finally, we present experimental results to verify the effectiveness of the velocity-based safety device.
A search for resonances decaying into a Higgs boson and a new particle X in the XH→qqbb final state with the ATLAS detector (2018)

A search for resonances decaying into a Higgs boson and a new particle X in the XH qqbb final state with the ATLAS detector .
Some observations on the mechanics and dynamics of tumor heterogeneity (2012)

The genetic, proteomic and cytostructural complexities of malignant neoplasms have received much attention in cancer research for many years. However, studies of the mechanics of neoplastic phenomena at the meso- and macroscales are also now providing opportunities for understanding some aspects of tumor growth and developing new therapeutic possibilities. We provide a brief overview of some of the recent work in these areas, with emphasis on physical considerations of certain aspects of the mechanics and fluid dynamics of tumor cell invasion and dispersion.
Transverse topology of glucose-6-phosphatase in rat hepatic endoplasmic reticulum (1991)

Antibodies raised against purified components of glucose-6-phosphatase were used to study the transmembrane orientation of the complex. Measurements of glucose-6-phosphatase activities and immunoblot analysis of sealed microsomes and detergent-solubilized microsomes after treatment with proteases suggested that most of the catalytic subunit resides within the lumen of the endoplasmic reticulum. In contrast, other components of glucose-6-phosphatase are accessible to the cytoplasm. Treatment of the partially purified glucose-6-phosphatase enzyme with glycopeptide N-glycosidase indicated that the catalytic subunit of the enzyme was a glycoprotein.
Transparent ceramic scintillators for gamma spectroscopy and radiography (2010)

Transparent ceramics combine the scintillation performance of single crystals with the ruggedness and processability of glass. We have developed a versatile, scaleable fabrication method, wherein nanoparticle feedstock is consolidated at temperatures well below melting to form inch-scale phase-pure transparent ceramics with optical scatter of &alpha; &lt;0.1 cm<sup>-1</sup>. We have fabricated Cerium-doped Gadolinium Garnets with light yields of ~50,000 Ph/MeV and energy resolution of &lt;5% at 662 keV. We have also developed methods to form sheets of the high-Z ceramic scintillator, Europium-doped Lutetium Oxide Bixbyite, producing ~75,000 Ph/MeV for radiographic imaging applications.
How do you manage your contacts if you can't read or write? (2006)

No abstract available.
Testing properties of dataflow program operators (2013)

Dataflow programming languages, which represent programs as graphs of data streams and operators, are becoming increasingly popular and being used to create a wide array of commercial software applications. The dependability of programs written in these languages, as well as the systems used to compile and run these programs, hinges on the correctness of the semantic properties associated with operators. Unfortunately, these properties are often poorly defined, and frequently are not checked, and this can lead to a wide range of problems in the programs that use the operators. In this paper we present an approach for improving the dependability of dataflow programs by checking operators for necessary properties. Our approach is dynamic, and involves generating tests whose results are checked to determine whether specific properties hold or not. We present empirical data that shows that our approach is both effective and efficient at assessing the status of properties.
Microbiology in Europe (2014)

Graphical Abstract Figure.Open in new tabDownload slideSelection of 1 FEMS articles from all across Europe.
Cellular Immunity Elicited by Human Immunodeficiency Virus Type 1/ Simian Immunodeficiency Virus DNA Vaccination Does Not Augment the Sterile Protection Afforded by Passive Infusion of Neutralizing Antibodies (2003)

High levels of infused anti-human immunodeficiency virus type 1 (HIV-1) neutralizing monoclonal antibodies (MAbs) can completely protect macaque monkeys against mucosal chimeric simian-human immunodeficiency virus (SHIV) infection. Antibody levels below the protective threshold do not prevent infection but can substantially reduce plasma viremia. To assess if HIV-1/SIV-specific cellular immunity could combine with antibodies to produce sterile protection, we studied the effect of a suboptimal infusion of anti-HIV-1 neutralizing antibodies in macaques with active cellular immunity induced by interleukin-2 (IL-2)-adjuvanted DNA immunization. Twenty female macaques were divided into four groups: (i). DNA immunization plus irrelevant antibody, (ii). DNA immunization plus infusion of neutralizing MAbs 2F5 and 2G12, (iii). sham DNA plus 2F5 and 2G12, and (iv). sham DNA plus irrelevant antibody. DNA-immunized monkeys developed CD4 and CD8 T-cell responses as measured by epitope-specific tetramer staining and by pooled peptide ELISPOT assays for gamma interferon-secreting cells. After vaginal challenge, DNA-immunized animals that received irrelevant antibody became SHIV infected but displayed lower plasma viremia than control animals. Complete protection against SHIV challenge occurred in three animals that received sham DNA plus MAbs 2F5 and 2G12 and in two animals that received the DNA vaccine plus MAbs 2F5 and 2G12. Thus, although DNA immunization produced robust HIV-specific T-cell responses, we were unable to demonstrate that these responses contributed to the sterile protection mediated by passive infusion of neutralizing antibodies. These data suggest that although effector T cells can limit viral replication, they are not able to assist humoral immunity to prevent the establishment of initial infection.
Tuning in to Noise (1996)

Two sweeping generalizations can be made about most natural systems: They are intrinsically nonlinear and they operate in noisy environments. Examples abound, ranging from weather systems to oscillating chemical reactions to the movements of an eel. The most complex example is arguably the human central nervous system, flooded as it is with the “noise” of modern life.
Correlation analyses of clinical and molecular findings identify candidate biological pathways in systemic juvenile idiopathic arthritis (2012)

The strong correlation between pathways implicated in elevations of both ESR and JC in SJIA argues that the systemic and arthritic components of the disease are related mechanistically. Inflammatory pathways in SJIA are distinct from those in POLY course JIA, consistent with differences in clinically appreciated target organs. The limited number of ESR-related SJIA genes that also are associated with elevations of ESR in POLY implies that the SJIA associations are specific for SJIA, at least to some degree. The distinct pathways associated with arthritis in early and late SJIA raise the possibility that different immunobiology underlies arthritis over the course of SJIA.
Capacity Scaling of Multi-User MIMO with Limited Feedback in a Multi-Cell Environment (2007)

We demonstrate that the fundamental capacity scaling law of multiple-input multiple-output radio systems, being proportional to the minimum of the number of receive and transmit antennas, holds also for the interference-limited multi-user multi-cell downlink scenario. It can be realized by using a sophisticated combination of physical and medium access control layer algorithms. The algorithms have low complexity and require no coherent channel state information at the transmitter. Instead, limited feedback on the effective channel quality is provided via a low-rate control channel. Our set of algorithms offers a fixed grid of beams at the transmitter, where the terminals can select the best beam set. Further, we use receivers exploiting the instantaneous knowledge of the interference at the terminal side. A score-based scheduler, which asymptotically reaches proportional fairness, is used to switch adaptively between multi-user diversity and multi-user multiplexing, in a frequency-selective manner. We provide many insights into the synergy between these algorithms from multi-cell simulations in a hexagonal cellular deployment.
Abstract 5574: ZNF516 and FKBP6 promoter hypermethylation as a potential companion diagnostic panel for HPV-positive and inconclusive-Pap women (2012)

Abstract New biomarkers are needed to improve cervical cancer screening technologies, which are mostly based on cytological examination since the 1940's. HPV testing has been adopted for the triage of patients after a cervical cytology-screening test. HPV testing is now also increasingly used for screening in conjunction with cervical cytology. However, a percentage of HPV-positive and inconclusive-Pap women have negative biopsies when refered to colposcopy clinics. The aim of this study was to use a genome-wide discovery approach to identify novel epigenetic biomarkers for cervical cancer, which could be used as companion diagnostic panels to HPV and PAP. DNA from twelve normal and seven cervical cancer samples was enriched with Methylated DNA Immunoprecipitation (MeDIP), hybridized to Nimblegen 385K CpG Islands plus Promoter arrays and validated by quantitative Methylation Specific PCR in discovery (n=49) and prevalence cohorts (n=108). After correction and normalization performed using Nimblegen algorithms genes methylated in tumor and not in normal samples were ranked by methylation peak values and sequence homology. The most significant loci were verified against a report by Ongenaert et al. (BMC Med Genomics, 2008) that uses a relaxation ranking algorithm to identify re-expressed genes in cervical cancer cell lines after treatment with demethyalting agents. Two genes, ZNF516 and FKBP6, were identified as candidate epigenomic biomarkers after rigourous bioinformatics and in-silico analyses. These genes were also found to be re-expressed by Ongenaert et al. Using the most optimal cut-off as determined by ROC, ZNF516 promoter methylation had 90% sensitivity and 95% specificity (AUC=0.95) in the discovery cohort. FKBP6 promoter methylation had a sensitivity of 73% and a specificity of 79% in the same cohort. Promoter methylation of FKBP6 (OR=4.51, 95%C.I.=2.04-9.97, P&amp;lt;0.001) and ZNF516 (OR=11.84, 95%C.I.=4.59-30.57, P&amp;lt;0.001) was associated to HPV infection in the prevalence cohort. FKBP6 (OR=7.15, 95%C.I.=1.45-35.34, P=0.01) and ZNF516 (OR=26.72, 95%C.I.=2.61-273.05, P &amp;lt;0.01) promoter methylation was associated with histological diagnosis of cervical cancer in the overall cohort, after controlling for age and HPV infection. Promoter methylation of ZNF516 and FKBP6 performed better than HPV at identifying normal from tumor tissue in the overall cohort. Our results suggest that a genome-wide approach using MeDIP-Chip and qMSP is useful for identifying novel screening and diagnostic markers. ZNF516 and FKBP6 were identified as a potential companion diagnostic panel for HPV-positive and inconclusive-Pap women. Examination of these biomarkers in a larger, independent cohort is warranted. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 103rd Annual Meeting of the American Association for Cancer Research; 2012 Mar 31-Apr 4; Chicago, IL. Philadelphia (PA): AACR; Cancer Res 2012;72(8 Suppl):Abstract nr 5574. doi:1538-7445.AM2012-5574