gebhart/patrepeval huggingface dataset:
Textile supercapacitors-based on MnO2/SWNT/conducting polymer ternary composites (2015)

This paper describes a simple and fast process for the fabrication of flexible and textile-based supercapacitors. Symmetric electrodes made up of binder-free ternary composites of manganese oxide (MnO2) nanoparticles, single walled carbon nanotubes (SWNT) and a conducting polymer (either polyaniline (PANI) or poly(3,4-ethylenedioxythiophene)–poly(styrenesulfonate) (PEDOT:PSS)) were layer-by-layer deposited onto cotton substrates by dip coating method. Solid-state supercapacitor devices were assembled using a gel electrolyte. Specific capacitances of 294 F/g and 246 F/g were obtained for MnO2/SWNT/PANI and MnO2/SWNT/PEDOT:PSS ternary nanocomposite supercapacitors, respectively. Power densities for these supercapacitors were 746.5 W/kg and 640.5 W/kg for MnO2/SWNT/PANI and MnO2/SWNT/PEDOT:PSS, respectively. Good capacity retention (more than 70%) upon cycling over 1000 times was achieved for both electrode compositions. Supercapacitors demonstrated in this work would be well suited as disposable power sources for wearable and intelligent textiles. Copyright © 2015 John Wiley & Sons, Ltd.
Budesonide for Maintenance of Remission in Patients with Crohn's Disease in Medically Induced Remission: A Predetermined Pooled Analysis of Four Randomized, Double-Blind, Placebo-Controlled Trials (2005)

Budesonide 6 mg/day is effective for prolonging time to relapse and for significantly reducing rates of relapse at 3 and 6 months but not 12 months in patients with CD in medically induced remission.
Pronunciation Alphabet Registry (2009)

This document describes a new registry for Pronunciation Alphabets,
such as pinyin, that can be used to describe pronunciations of words
and phrases in a particular language.
The role of epidermal growth factor receptor (EGFR)-directed recombinant dimeric IgA antibodies in tumor cell killing. (2011)

e13014 Background: The epidermal growth factor receptor (EGFR) is a validated target for personalized cancer therapy with IgG antibodies. IgA antibodies contribute to the humoral part of the mucosal immune system, but their immunotherapeutic potential has hardly been explored. Here, we describe the production, purification and functional evaluation of recombinant dimeric IgA antibodies against EGFR. Methods: Human J-chain-containing IgA was produced under serum-free conditions by transfecting non-adherent CHO-K1 cells expressing EGFR-specific monomeric 225-IgA (mIgA) with a vector coding for His-tagged human J-chain. Dimeric IgA (dIgA) was purified by two different affinity (anti-human-κ and anti-His-tag) and one size exclusion chromatography. The resulting homogenous preparation of highly pure IgA dimers was biochemically and functionally characterized. Results: Functional studies demonstrated dIgA to be at least as effective as mIgA in triggering antibody-dependent cellular cytotoxicity of A431 tumor cells by isolated monocytes (EC50 1.9/0.8 nM for mIgA/dIgA), by isolated PMN (EC50 5.6/3.7 nM for mIgA/dIgA) and in human whole blood 51chromium-release-assays (EC50 1.8/1.4 nM for mIgA/dIgA). Importantly, dimeric IgA was more effective in F(ab)-mediated mechanisms: inhibition of binding of FITC-labelled EGF to A431 cells and furthermore downmodulation of EGFR by dIgA was achieved at significantly lower concentrations than by mIgA (EC50 14.9/124.5 nM, 76.2/335.2 nM, respectively). In addition, growth of EGFR-expressing DiFi cells was inhibited more effectively by dimeric than by monomeric IgA (EC50 6.2/49.7 nM). Furthermore, only dimeric but not monomeric IgA or IgG was directionally transported via the pIgR through an epithelial cell monolayer in a transcytosis assay with polarized MDCK cells stably transfected with human polymeric immunoglobulin receptor (pIgR). Conclusions: These studies demonstrate that recombinant dimeric IgA antibodies against EGFR trigger a distinct repertoire of effector functions compared to monomeric IgA or IgG1 antibodies - suggesting that dimeric IgA antibodies may constitute an interesting antibody format for tumor therapy.
Scale-down methodology to study the effect of fluid dynamic stress and oxygen gradients on filamentous fungal fermentations producing cellulases (2021)

International audience
Glutamate and GABA Receptors and Transporters (2001)

1. Ionotropic Glutamate Receptors: Functional and Pharmacological Properties in Relation to Constituent Subunits, Stuart G. Cull-Candy 2. Molecular Structure of Ionotropic Glutamate Receptors, Jan Egebjerg and Henrik S Jensen 3. Glutamate Receptor Trafficking, Guido Meyer and Jeremy M. Henley 4. Pharmacology of NMDA Receptors, David E. Jane 5. Pharmacology of AMPA/kainate Receptors, Ulf Madsen, Tommy N. Johansen, Tine B. Stensbol and Povl Krogsgaard-Larsen 6. Metabotropic Glutamate Receptors (mGluRs): Structure and Functions, J-P. Pin, L. Fagni and J. Bockaert 7. Pharmacology of Metabotropic Receptors, Darryle D. Schoepp and James A. Monn 8. Insights into GABAA Receptor Complexity From the Study of Cerebellar Granule Cells: Synaptic and Extrasynaptic Receptors, William Wisden and Mark Farrant 9. GABAA Receptor Complex: Structure and Function, Richard W. Olsen and Robert L. Macdonald 10. GABAA Receptor Complex: Structural Requirements for Ligand Interactions, P. Krogsgaard-Larsen, B. Ebert, U. Kristiansen, B. Madsen 11. Molecular Structure of the GABAB Receptors, N. Klix and B. Bettler 12. Phamacology of GABAB Receptors, N. G. Bowery 13. Structure, Function and Regulation of Glutamate Transporters, Line M. Levy 14. GABA Transporters: Functional and Pharmacological Properties, Arne Schousboe and Baruch Kanner 15. Transgenic Models for Glutamate Receptor Function, A.J. Doherty and G.L. Collingridge 16. Transgenic Models for GABAA Receptor Function, H. Mohler 17. Glutamatergic transmission: Therapeutic Prospects for Schizophrenia and Alzheimer's Disease, Nuri B. Farber, John W. Newcomer and John W. Olney 18. GABA-ergic Transmission: Therapeutic Prospects, Christian Thomsen and Bjarke Ebert MRC Centre, UK, R. Dingledine, Emory University of Medicine, USA, D.E. Jane, Univeristy of Bristol, UK, U. Madsen, Danish School of Pharmacy, S. Nakanishi, Kyoto University Faculty of Medicine, Japan, P.L. Ornstien and D.D. Schoepp, Lilly Corporate Centre, USA, M. Neilsen, St Hans Hospital, Denmark, R.L. Macdonald, University of Michegan Medical Centre, USA and R. Olsen, University of California, USA, P. Krogsgaard-Larsen, Danish School of Pharmacy, B. Bettler, Novartis Pharma Inc., Switzerland, W. Froestl, Novartis Pharma Inc., Switzerland, G. Gegelashvili, Danish School of Pharmacy, N.C. Damnbolt, University of Oslo, Norway, A. Shousboe, Danish School of Pharmacy, B.I. Kanner, The Hebrew University, Israel, G.L. Collingridge, Bristol University, UK, E. Mohler, Institute of Pharmacology, Switzerland, J. Drejer, NeuroSearch, Denmark, A.G. Chapman, Institute of Psychiatry, UK.
Effect of microwave power on morphology of AgO thin film grown using microwave plasma CVD (2017)

In this study, pure silver (Ag) thin film of 8 nm was deposited onto glass substrate by using radio frequency (RF) sputtering technique and was then exposed to microwave assisted oxygen plasma generated by microwave plasma CVD. The oxidation of Ag into AgO thin film was studied using varying microwave power. The influence of microwave power on morphology and size of oxide film was investigated. The crystal structure, crystal size, chemical composition, morphologies and optical properties of oxidised silver thin film (AgO) was characterised by using x-ray powder diffraction (XRD), field emission scanning electron microscopy (FESEM), Raman spectroscopy and UV-vis spectroscopy. Morphological characterisation of these films reveals a systematic change from metallic silver (Ag) to silver oxide (AgO). The size of AgO thin film was calculated using Scherrer equation and was observed to be 11 nm, 12 nm and 13.5 nm at 400 W, 800 W and 1200 W respectively. A considerable change in UV-vis spectra was observed with increase in annealing temperature.
Hybrid zero-voltage switching (ZVS) control for power inverters (2023)

A power inverter combination includes a half-bridge power inverter including first and second semiconductor power switches receiving input power having an intermediate node therebetween providing an inductor current through an inductor. A controller includes input comparison circuitry receiving the inductor current having outputs coupled to first inputs of pulse width modulation (PWM) generation circuitry, and a predictive control block having an output coupled to second inputs of the PWM generation circuitry. The predictive control block is coupled to receive a measure of Vin and an output voltage at a grid connection point. A memory stores a current control algorithm configured for resetting a PWM period for a switching signal applied to control nodes of the first and second power switch whenever the inductor current reaches a predetermined upper limit or a predetermined lower limit.
Optical properties of single-crystalline ZnO nanowires on m-sapphire (2003)

ZnO nanowires have been synthesized using a catalyst-assisted heteroepitaxial carbothermal reduction approach on a m-sapphire substrate. Intricate and uniform arrays have been obtained with each nanowire forming an angle ∼30° with the substrate normal. Photoluminescence studies at room temperature for wavelengths between 335 and 620 nm reveal a strong single exciton peak at ∼380 nm (3.26 eV) with accompanying deep-level blueshifted emission peaks at ∼486, 490, and 510 nm. UV resonant Raman spectroscopy has been used to characterize the nanowires at room temperature with multiphonon scattering exhibiting phonon quantum confinement.
Neurophysiological Assessment of the Feasibility and Safety of Neural Tissue Transplantation in Patients with Syringomyelia (2001)

The feasibility and safety of a procedure involving fetal spinal cord tissue transplantation in patients with syringomyelia was assessed using a neurophysiological protocol designed to quantitate peripheral nerve function, spinal cord reflex excitability, and spinal cord conduction pathways essential for somatosensory evoked potentials. We report here data obtained before and for 18 months following the transplantation procedure performed on the first two patients in this study. The neurophysiological assessment protocols included measures of cortical and spinal cord evoked potentials, H-reflex excitability, and peripheral nerve conduction. Prior to the procedure, both patients had significant deficits on some of the neurophysiological measures, for example, lower extremity cortical evoked potentials. However, robust measures of intact pathways, such as upper extremity cortical evoked potentials, were also observed preoperatively in both patients. Thus, it was anticipated that conduction in these intact pathways could be at risk either from complications from the transplantation procedure and/or from continued expansion of the syrinx. Following the transplantation procedure, no negative changes were observed in any of the neurophysiological measures in either patient. In addition, patient 1 showed a decrease in the rate potentiation of tibial H-reflexes on the right side and an increase in the response probability of left tibial H-reflexes. The results of this postoperative longitudinal assessment provide a first-level demonstration of the safety of the intraspinal neural tissue transplantation procedure. However, the consideration of safety is currently limited to the grafting procedure itself, since the long-term fates of the donor tissue in these two patients remain to be shown more definitively.
An Automatic Wavelength Control Method of a Tunable Laser for a WDM-PON (2009)

We propose a novel automatic wavelength control method of a tunable laser for a wavelength-division-multiplexed passive optical network (WDM-PON). By sending a low-power amplified spontaneous emission light generated from a broadband light source (BLS) to a tunable laser through a wavelength-division multiplexer, we match the wavelength of the tunable laser to a peak transmission wavelength of the multiplexer. The deviation of the wavelength of the tunable laser was less than 0.05 nm from the center of the target channel. We demonstrate up to 10-Gb/s transmission in a WDM-PON by using the proposed method. We also show that system impairments induced by the BLS are negligible.
Futures of Democratic Finance (2021)

Chapter five extends our argument by reflecting on the potential futures of crowdfunding and the democratization of finance. We explore the paradox of financial inclusion; the idea of investment as a social act surrounded by long-standing taboos; and, how mainstream finance today is far more interested in managing the existing wealth of the rich than in creating it for the poorer members of society. Since there are also those who read the innovations of Bitcoin and other cryptocurrencies and cryptoassets through the lens of democratic finance, we show how this market is driven by a very different worldview to the one we see embodied in crowdfunding.
Athletes Demonstrate Superior Dynamic Visual Acuity (2021)

Athletes have superior dynamic visual acuity performance compared with controls at 30°/s. This between-group difference cannot be fully explained by differences in smooth pursuit eye movements and therefore may reflect other differences between the groups.
Anti-HIV B Cell Lines as Candidate Vaccine Biosensors (2012)

Challenge studies following passive immunization with neutralizing Abs suggest that an HIV vaccine could be efficacious were it able to elicit broadly neutralizing Abs (bNAbs). To better understand the requirements for activation of B cells producing bNAbs, we generated cell lines expressing bNAbs or their germline-reverted versions (gl-bNAbs) as BCRs. We then tested the abilities of the bNAb-expressing cells to recognize HIV pseudovirions and vaccine candidate proteins by binding and activation assays. The results suggest that HIV envelope (Env) Ag-expressing, infection-competent virions are poorly recognized by high-affinity bNAb-expressing cells, as measured by the inability of Ags to induce rapid increases in intracellular calcium levels. Other Ag forms appear to be highly stimulatory, in particular, soluble gp140 trimers and a multimerized, scaffolded epitope protein. Virions failed to efficiently activate bNAb-expressing B cells owing to delayed or inefficient BCR recognition, most likely caused by the low density of Env spikes. Importantly, B cells carrying gl-bNAb BCRs were not stimulated by any of the tested vaccine candidates. These data provide insight into why many HIV immunogens, as well as natural HIV infections, fail to rapidly stimulate bNAb responses and suggest that bNAb-expressing cell lines might be useful tools in evaluation of vaccine Ags for infectious diseases. Because soluble Env trimers or multimerized scaffolded epitopes are best at activating B cell-expressing bNAbs, these antigenic forms should be considered as preferred vaccine components, although they should be modified to better target naive gl-bNAb B cells.
Carney complex syndrome manifesting as cardioembolic stroke: a case report and review of the literature (2020)

The co-occurrence of emboligenic cardiac myxomas and skin lesions should be an indication for screening for CNC.
Scaling of fracture energy in tensile debonding of viscoelastic films (2007)

The work done to separate viscoelastic adherends is often dominated by energy dissipation due to the bulk deformation that accompanies the intrinsic processes of interfacial separation. The inter-relationship between bulk and interfacial deformation processes is studied here by analyzing a one-dimensional model for steady-state crack propagation between a rigid substrate and a thin viscoelastic film when the latter is subjected to tensile loading and the former is fixed. The viscoelastic layer is represented by a standard linear solid and is connected to the rigid substrate via a Dugdale cohesive zone model. The principal result of the analysis is a prediction for the dependence of the total work of fracture on the rate of loading. A threshold crack-tip velocity that governs the onset of dissipation is determined as a function of the film thickness and the interfacial and viscoelastic parameters of the film. Based on the ratio of the crack-tip velocity to the threshold velocity, three velocity regimes are identified where the energy dissipation is low, high, or intermediate. These correspond, respectively, to the overlap of the cohesive zone with the film material that is completely relaxed, is completely unrelaxed, or is in the process of relaxation. An approximate solution for the scaling of fracture energy in these three regimes has been presented. Finally, the relevance of these results to a two-dimensional problem is discussed.
Barriers and enablers to managing obesity in general practice: a practical approach for use in implementation activities. (2012)

This pragmatic study found that there are many barriers to the implementation of NICE guidance on obesity, involving patients, practitioners and support services for primary care.
Charge generation in organic solar cell materials studied by terahertz spectroscopy (2015)

We have investigated the photophysics in neat films of conjugated polymer PBDTTPD and its blend with PCBM using terahertz time-domain spectroscopy. This material has very high efficiency when used in organic solar cells. We were able to identify a THz signature for bound excitons in neat PBDTTPD films, pointing to important delocalization in those excitons. Then, we investigated the nature and local mobility (orders of magnitude higher than bulk mobility) of charges in the PBDTTPPD:PCBM blend as a function of excitation wavelength, fluence and pump-probe time delay. At low pump fluence (no bimolecular recombination phenomena), we were able to observe prompt and delayed charge generation components, the latter originating from excitons created in neat polymer domains which, thanks to delocalization, could reach the PCBM interface and dissociate to charges on a time scale of 1 ps. The nature of the photogenerated charges did not change between 0.5 ps and 800 ps after photo-excitation, which indicated that the excitons split directly into relatively free charges on an ultrafast time scale.
Dielectric Studies of Blends of Poly(ethylene oxide) and Poly(styrene-co-p-hydroxystyrene). Semicrystalline Blends (2004)

The segmental and local dynamics of semicrystalline, melt-miscible blends of poly(ethylene oxide) [PEO] and a poly(styrene-co-p-hydroxystyrene) copolymer [SHS] were investigated using dielectric relaxation spectroscopy (DRS). A broad, yet well-defined, DRS segmental process is observed for the 5 wt % SHS blend, and it gradually shifts to higher temperature and broadens further with increasing SHS content. It can be distinguished in the 3D spectrum of the 10 wt % SHS blend, but it is only barely discernible in the spectrum of the 15 wt % SHS blend, as it is masked by large low frequency losses likely arising from electrode polarization. On the basis of current and previous findings, we propose that the observed segmental process is comprised of a slower cooperative segmental relaxation involving both components, as well as a faster process due to less associated PEO segments. Furthermore, heterogeneous spatial distribution of the SHS segments also promotes broadening of the segmental process in these blends, particularly at higher SHS contents. Hydrogen-bonded hydroxystyrene units produce a βS1 process, which is more cooperative than typical local relaxations, in light of its activation energy and the temperature insensitivity of its relaxation strength. All blends exhibit a high-frequency γb relaxation, near the γPEO and SHS βS2 processes of the neat components. The f−T locations of the γb relaxation in the various blends are the same within experimental error, and they are closer to the γPEO than to SHS βS2 process.
ChemInform Abstract: Platinum/γ‐Al2O3 Catalytic Membrane: Preparation, Morphological, and Catalytic Characterizations. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
[A case of lower esophageal muscular ring presenting with dysphagia]. (2003)

There are diverse ring-like narrowings in the lower esophagus: mucosal ring, muscular ring, ring-like annular peptic stricture. Esophageal muscular ring is extremely rare and generally asymptomatic. It occurs at the proximal border of the esophageal vestibule that corresponds to the upper end of the lower esophageal sphincter. We experienced a case of lower esophageal muscular ring with a symptom of intermittent mild dysphagia for 40 years and report the findings with a review of the literature.
Table S1 from Identification of Membrane-expressed CAPRIN-1 as a Novel and Universal Cancer Target, and Generation of a Therapeutic Anti-CAPRIN-1 Antibody TRK-950 (2023)

&lt;p&gt;Clinical, pathological findings in the toxicity study in Cynomolgus Monkeys&lt;/p&gt;
2D Molybdenum Disulfide Nanosheets As Functional Electroactive Materials and Additives for Lithium and Lithium Sulfur Based Batteries (2020)

The 2D structured dichalcogenide molybdenum(IV) sulfide (MoS 2 ) has generated significant interest for Li ion batteries due to its high theoretical capacity, good rate capability, and minimal volume changes during cycling. To enable full realization of MoS 2 as an electroactive material, an important and continuing challenge is to understand the many polymorphs of MoS 2 that can be (de)stabilized by electrochemical lithiation and nanosizing. Characteriation of bulk MoS 2 and nanosheet-type MoS 2 as solids, both structurally (X-ray diffraction (XRD), X-ray absorption spectroscopy (XAS)) and compositionally (X-ray photoelectron spectroscopy (XPS), inductively coupled plasma-optical emission spectroscopy (ICP-OES)) will be described to rationalize observed differences in capacity and efficiency in lithium based cells. X-ray analysis compatible lithium cells ( in situ XRD and ex situ XAS) measurements of the specific phase changes to rationalize the significant difference in electrochemistry between the nanosheet and bulk materials upon (de)lithiation will also be discussed. The application of 2D MoS 2 nanosheets for lithium sulfur batteries (Li−S) will also be described. Significantly improved Li−S electrochemistry in an environmentally friendly electrolyte solvent is demonstrated through implementation of MoS 2 nanosheet materials as cathode additives, leading to improved capacity retention upon extended cycling in lithium sulfur cells. The findings will be discussed in light of the unique attributes of the MoS 2 atomic level (2D) and mesoscale (3D) heterostructure.