gebhart/patrepeval huggingface dataset:
Complementary GaAs SIS FET inverter using selective crystal regrowth technique by MBE (1986)

A first complementary GaAs semiconductor-insulator-semiconductor (SIS) FET inverter has been fabricated by constructing n-channel and p-channel GaAs SIS FET's on a single LEC GaAs substrate using MBE selective crystal regrowth technique. The fabricated inverter shows an inverter operation as a really low-power complementary inverter.
Towards backscatter tensor imaging (BTI): Analysis of the spatial coherence of ultrasonic speckle in anisotropic soft tissues (2013)

The assessment of fiber architecture is of major interest in the progression of myocardial disease. Recent techniques such as MR Diffusion Tensor Imaging or Ultrasound Elastic Tensor Imaging (ETI) can derive the fiber directions by measuring the anisotropy of water diffusion or tissue lasticity, but these techniques present severe limitations in clinical setting. In this study, we measure the spatial coherence of ultrasonic speckle in skeletal muscles and myocardial tissues, in order to determine the fibers directions and compare it to ETI. Acquisitions were performed using a linear transducer array mounted on a rotation device to image ex vivo bovine skeletal muscle and porcine LV myocardial samples. At each angle, multiple plane waves were transmitted and the backscattered echoes recorded. The coherence factor was measured as the integral of the correlation function. In skeletal muscle, maximal/minimal coherence factor was found for the probe parallel/perpendicular to the fibers. In myocardium, the coherence was assessed across the entire myocardial thickness, and the position of maxima and minima varied transmurally due to the complex fibers distribution. The shear wave speed variation with the probe angle was found to follow the coherence variation. Spatial correlation can thus reveal the anisotropy of the ultrasonic speckle in skeletal muscle and myocardium. BTI could be used on any type of ultrasonic scanner for non invasive evaluation of myocardial fibers.
Identification of C12orf4 as a gene for autosomal recessive intellectual disability (2016)

Intellectual disability (ID) is a major health problem in our society. Genetic causes of ID remain unknown because of its vast heterogeneity. Here we report two Finnish families and one Dutch family with affected individuals presenting with mild to moderate ID, neuropsychiatric symptoms and delayed speech development. By utilizing whole exome sequencing (WES), we identified a founder missense variant c.983T>C (p.Leu328Pro) in seven affected individuals from two Finnish consanguineous families and a deletion c.799_1034-429delinsTTATGA (p.Gln267fs) in one affected individual from a consanguineous Dutch family in the C12orf4 gene on chromosome 12. Both the variants co-segregated in the respective families as an autosomal recessive trait. Screening of the p.Leu328Pro variant showed enrichment in the North Eastern sub-isolate of Finland among anonymous local blood donors with a carrier frequency of 1:53, similar to other disease mutations with a founder effect in that region. To date, only one Arab family with a three affected individuals with a frameshift insertion variant in C12orf4 has been reported. In summary, we expand and establish the clinical and mutational spectrum of C12orf4 variants. Our findings implicate C12orf4 as a causative gene for autosomal recessive ID.
Computational and Experimental Study of Fluorine Doped (Mn1–xNbx)O2 Nanorod Electrocatalysts for Acid-Mediated Oxygen Evolution Reaction (2019)

Identification, development, and engineering of high-performance, earth-abundant, and cost-effective precious group metal (PGM)-free electrocatalysts for catalyzing oxygen evolution reaction (OER) in acidic electrolytes are vital for the commercialization of proton exchange membrane based water electrolysis (PEMWE) technology. Utilizing the density functional theory (DFT) calculations to rationalize the thermodynamics and kinetics of adsorption of OER, juxtaposed with cohesive energy and electronic structure, we report the generation of 10 wt % fluorine (F)-doped (Mn1–xNbx)O2:10F nanorods (NRs) as active and durable PGM-free solid solution electrocatalysts for acid-mediated OER. The DFT calculations reveal an optimal solid solution composition of (Mn0.8Nb0.2)O2:10F containing Nb and F in α-MnO2 structure, exhibiting the optimized surface electronic structure (ΔG for the OER rate-determining step ∼ 1.72 eV) and cohesive energy (Ecoh ∼ −16.30 eV/(formula unit)) for OER, contributing to its higher catalytic performance in comparison to α-MnO2. Consequently, (Mn1–xNbx)O2:10F compositions with well-defined one-dimensional (1D) nanorod architectures are synthesized with the optimal composition of (Mn0.8Nb0.2)O2:10F, demonstrating improved electrocatalytic performance for acidic OER in good agreement with the DFT calculations. The superior electrochemical performance of (Mn0.8Nb0.2)O2:10F NRs includes significantly lower charge transfer resistance (∼11.8 Ω cm2), lower Tafel slope (∼371.17 mV dec–1), lower overpotential to deliver a current density of 10 mA cm–2geo (∼0.68 V), higher mass activity (∼29 A g–1), large electrochemically active surface area (ECSA ∼ 26.28 m2g–1), and turnover frequency (TOF ∼ 0.0065 s–1) with higher BET and ECSA normalized activity (∼0.5 mA cm–2BET and 0.11 mA cm–2ECSA) contrasted with (Mn1–xNbx)O2:10F (x = 0, 0.1, and 0.3) compositions, at an overpotential of 0.67 mV. Further, (Mn0.8Nb0.2)O2:10F NRs exhibit good electrochemical stability in acidic OER regimes, with no substantial catalytic activity degradation, validating its structural robustness for prolonged OER and making it a promising PGM-free OER electrocatalyst for acid-mediated PEMWE.
A Fast, Autonomous, Bipedal Walking Behavior over Rapid Regions (2022)

In trying to build humanoid robots that perform useful tasks in a world built for humans, we address the problem of autonomous locomotion. Humanoid robot planning and control algorithms for walking over rough terrain are becoming increasingly capable. At the same time, commercially available depth cameras have been getting more accurate and GPU computing has become a primary tool in AI research. In this paper, we present a newly constructed behavior control system for achieving fast, autonomous, bipedal walking, without pauses or deliberation. We achieve this using a recently published rapid planar regions perception algorithm, a height map based body path planner, an A* footstep planner, and a momentum-based walking controller. We put these elements together to form a behavior control system supported by modern software development practices and simulation tools.
Plasmon hybridization in three-dimensional magnetic metamolecules (2014)

In the past decade, a number of interesting designs have been proposed to generate artificial magnetism at optical frequencies using plasmonic metamaterials, but owing to the planar configurations of typically fabricated meta-molecules that make up the metamaterials, the magnetic response is mainly driven by the electric field of incident electromagnetic wave.In this work, we have fabricated 3D split-ring resonators (SRRs) [1] which allowed us to study how incident electromagnetic fields interact with these 3D SRRs and to reveal the plasmon coupling between closely spaced SRR dimers.
Modeling of Catalyst Deactivation in Bioethanol Dehydration Reactor (2019)

The catalytic ethanol dehydration route is a reality for the production of polyethylene from renewable sources. Ethanol dehydration process is performed in the presence of acid catalysts, under temperatures ranging from 500 K to 800 K, obtaining ethylene selectivity ranging from 95% to 99% and ethanol conversion of >98%. Despite the favorable values of conversion and selectivity, catalyst deactivation by coking is a well-known phenomenon that occurs in this process. This phenomenon leads to catalyst regeneration cycles, given that the catalyst’s life cycle is dependent on the process operating conditions. Thus, obtaining a mathematical model to optimize the ethanol dehydration process is of great interest to industry, allowing process optimization and optimal design of reactors. This work presents a phenomenological model of an ethanol dehydration fixed-bed reactor considering the catalyst deactivation and several chemical species. The developed mathematical model for catalyst deactivation considers species present in the reaction system as coke precursors. The predictive ability of the model, which has been validated with industrial plant data, are shown in the results, presenting deviations of <5% in the reactor temperature profile.
Abstract IA02: Regulation of growth by the mTOR pathway (2017)

Abstract mTOR is the target of the immunosuppressive and anti-cancer drug rapamycin and the central component of a nutrient- and hormone-sensitive signaling pathway that regulates cell growth and proliferation. We now appreciate that this pathway becomes deregulated in many human cancers and has key roles in the control of metabolism, cell and organ size, and aging. We have identified two distinct mTOR-containing proteins complexes, one of which regulates growth through S6K and another that regulates cell survival and metabolism through Akt. These complexes, called mTORC1 and mTORC2, define both rapamycin-sensitive and insensitive branches of the mTOR pathway. Over the last few years we have focused on how nutrients, particularly amino acids, regulate mTORC1. We have identified a complex signaling pathway that relays amino acid availability to mTORC1 through the heterodimeric Rag GTPases. We recently discovered several of the amino acid sensors for the pathway. I will discuss new results from our lab on the regulation and functions of mTORC1. Citation Format: David M. Sabatini. Regulation of growth by the mTOR pathway. [abstract]. In: Proceedings of the AACR Special Conference on Translational Control of Cancer: A New Frontier in Cancer Biology and Therapy; 2016 Oct 27-30; San Francisco, CA. Philadelphia (PA): AACR; Cancer Res 2017;77(6 Suppl):Abstract nr IA02.
Subchondral Fracture Following Arthroscopic Knee Surgery (2008)

This study provides pathologic evidence supporting the concept that subchondral fracture, and not osteonecrosis, is the major event in this rare complication following arthroscopy. Further investigation into the etiology of this condition is warranted.
Supplementary Figure 5A from Molecular Triage of Premalignant Lesions in Liquid-Based Cervical Cytology and Circulating Cell-Free DNA from Urine, Using a Panel of Methylated Human Papilloma Virus and Host Genes (2023)

&lt;p&gt;AlignScape - Pairwise alignment of the HPV16 genome with reads obtained from urine ccfDNA from seven clinical samples: TrDNA-445, TrDNA-455, TrDNA-456, TrDNA-481, TrDNA-504, TrDNA-513, and TrDNA-571. The large-scale HPV DNA server can produce a graphical 'large-scale' view of the pairwise alignments of up to twenty HPV genomes against a reference genome (HPV16 in this demo), together with annotations of genome rearrangement events.&lt;/p&gt;
Recent Advances in Microfabricated Gas Chromatography for Process Analysis. (2021)

Abstract not provided.
<title>Bunker view: limited-range head-motion-parallax visualization for complex data sets</title> (1994)

This work presents a head-motion-parallax visualization system for arbitrarily complex computer graphics databases (such as biomedical data sets) using precomputed images. It features a large rear-projection screen and a blind restricting the range of possible vantage points. We describe implementation details for the high-resolution low-lag prototype system and relate first reactions from users.
WWOX Inhibits Metastasis of Triple-Negative Breast Cancer Cells via Modulation of miRNAs (2019)

Triple-negative breast cancer (TNBC) is a heterogeneous, highly aggressive, and difficult to treat tumor type. The tumor suppressor <i>WWOX</i> spans FRA16D, a common fragile site that is commonly altered in breast cancer. Despite recent progress, the role of WWOX in TNBC metastasis is unknown. Here we report that WWOX inactivation correlates with advanced stages of TNBC and that its levels are frequently altered in TNBC cells. Ectopic restoration of WWOX in WWOX-negative TNBC cells inhibited metastasis while its depletion in WWOX-positive TNBC cells promoted metastasis. WWOX was a negative regulator of c-MYC, which regulated miR-146a expression and consequently fibronectin levels, contributing to an epithelial status of the cell. Treatment of TNBC cells with anti-miR-146a rescued the WWOX antimetastatic phenotype. Moreover, overexpression of MYC in WWOX-expressing TNBC cells overrode WWOX effects on miR-146a and fibronectin levels. Altogether, our data uncover an essential role for WWOX in antagonizing TNBC progression and highlight its potential use as a biomarker for metastasis. SIGNIFICANCE: These findings highlight the mechanism by which the tumor suppressor WWOX regulates metastasis of triple-negative breast cancer.<i>See related commentary by Sharma, p. 1746</i>.
Evaluation, Implementation and Performance of Write Permission Caching in the DSZOOM System (2004)

Fine-grained software-based distributed shared memory (SW-DSM) systems typically maintain coherence with in-line checking code at load and store operations to shared memory. The instrumentation overhead of this added checking code can be severe. This paper (1) shows that most of the instrumentation overhead in the fine-grained DSZOOM SW-DSM system is store related, (2) introduces a new write permission cache (WPC) technique that exploits spatial store locality and batches coherence actions at runtime, (3) evaluates WPC and (4) presents WPC results when implemented in a real SW-DSM system. On average, the WPC reduces the store instrumentation overhead in DSZOOM with 42 (67) percent for benchmarks compiled with maximum (minimum) compiler optimizations.
Thermal degradation of poly(vinyl chloride) blends (1990)

Abstract Poly(vinyl chloride) was mixed with various poly(methacrylate)s and polycarbonates by combined precipitation from common solutions. The thermal stability of the samples was measured at 180°C under nitrogen, the HCl evolved was detected by conductometry. UV‐Vis‐spectra of degraded samples were measured to investigate the influence of the poly(methacrylate)s on the lengths of polyenes formed during the degradation of poly(vinyl chloride). The experiments show that the nature of the ester group is the dominating factor for the thermal stability of poly(vinyl chloride) in these blends. Poly(n‐butylmethacrylate) exhibits the best stabilization for poly(vinyl chloride) in this series. Polycarbonates with a higher glass transition temperature than the temperature of degradation destabilize poly(vinyl chloride). Stabilization experiments with dibutyltin‐bis(isooctylthioglycolate) show a costabilizing effect of the poly(methacrylate)s and polycarbonates.
Recent Progress inOrganic Light-Emitting Devices (2007)

transferred to the vacuum chamber, Recentdevelopment in highperformance hole-transporting wideenergygap material organic light-emitting devices (OLEDs)willbe named3DTAPBPwasdeposited. discussed. A variety ofwide-energy-gap charge LiF/AI transport materials havebeenprepared andused Electron-transpo rting layer
Modified and unmodified technical lignins as flame retardants for polypropylene (2020)

Abstract Polyolefins used in building materials and furniture require the use of flame-retardant (FR) additives to improve their fire safety. Such additives should be safe to humans and the environment, and preferably bio-based. In the present work, the FR performance of unmodified and chemically modified technical lignins was compared to that of the ammonium polyphosphate/pentaerythritol (APP/PER) intumescent system in a polypropylene (PP) matrix. Micro-scale combustion calorimetry (MCC) was used to study the peak heat release rate (PHR), temperature at PHR (T PHR ), total heat release (THR) and char yield upon thermal decomposition of milligram-scale specimens. The PP/lignin composites showed up to 41% lower PHR and up to 36% lower THR compared to pure PP as well as large char residues. Based on the same parameters, especially the PP/lignin composites made with modified lignins outperformed the reference PP/APP/PER system and the PP/APP/lignin composites where unmodified lignin was used with APP. The most promising PP/lignin composites were prepared with partially demethylated/demethoxylated and depolymerised kraft lignin (‘CatLignin’), modified by the Mannich reaction to a nitrogen content of 13.5%.
Protein Precoating of Elastomeric Tissue-Engineering Scaffolds Increased Cellularity, Enhanced Extracellular Matrix Protein Production, and Differentially Regulated the Phenotypes of Circulating Endothelial Progenitor Cells (2007)

Scaffold precoating with extracellular matrix proteins can allow more precise "engineering" of cellular behavior in the development of tissue engineering of heart valves constructs by altering extracellular matrix production and cell phenotype.
Indium Incorporation into InGaN Quantum Wells Grown on GaN Narrow Stripes (2019)

InGaN quantum wells were grown using metalorganic chemical vapor phase epitaxy (vertical and horizontal types of reactors) on stripes made on GaN substrate. The stripe width was 5, 10, 20, 50, and 100 µm and their height was 4 and 1 µm. InGaN wells grown on stripes made in the direction perpendicular to the off-cut had a rough morphology and, therefore, this azimuth of stripes was not further explored. InGaN wells grown on the stripes made in the direction parallel to the GaN substrate off-cut had a step-flow-like morphology. For these samples (grown at low temperatures), we found out that the InGaN growth rate was higher for the narrower stripes. The higher growth rate induces a higher indium incorporation and a longer wavelength emission in photoluminescence measurements. This phenomenon is very clear for the 4 µm high stripes and less pronounced for the shallower 1 µm high stripes. The dependence of the emission wavelength on the stripe width paves a way to multicolor emitters.
Identification, structure, and characterization of an exopolysaccharide produced by Histophilus somniduring biofilm formation (2011)

H. somni is capable of producing a branching, mannose-galactose EPS polymer under growth conditions favorable to the biofilm phase of growth, and the EPS is a component of the biofilm matrix. The EPS can be sialylated in strains with sialyltransferase activity, resulting in enhanced density of the biofilm, and suggesting that EPS and biofilm formation may be important to persistence in the bovine host. The EPS may be critical to virulence if the biofilm state is required for H. somni to persist in systemic sites.
Quantum gravito-optics: a light route from semiclassical gravity to quantum gravity (2015)

Quantum gravity remains an elusive theory, in spite of our thorough understanding of the quantum theory and the general theory of relativity separately, presumably due to the lack of any observational clues. We argue that the theory of quantum gravity has a strong constraining anchor in the sector of gravitational radiation ensuring reliable physical clues, albeit in a limited observable form. In particular, all types of gravitational waves expected to be observable in LIGO-like advanced detectors are fully quantum mechanical states of radiation. Exact equivalence of the full quantum gravity theory with the familiar semiclassical theory is ensured in the radiation sector, in most real situations where the relevant quantum operator functions are normal ordered, by the analogue of the optical equivalence theorem in quantum optics. We show that this is indeed the case for detection of the waves from a massive binary system, a single gravitational atom, that emits coherent radiation. The idea of quantum-gravitational optics can assist in guiding along the fuzzy roads to quantum gravity.
The evolution of SOC interconnect and how NOC fits within it (2010)

In this paper, we describe "The Evolution of SOC Interconnect and How NOC Fits Within It" which is being presented during the "A Decade of NOC Research - Where Do We Stand?" session at DAC 2010.
Radar-Based Gesture Recognition Using a Variational Autoencoder With Deep Statistical Metric Learning (2022)

Radar-based gesture recognition systems are a promising concept for new human–machine interfaces. However, the systems are sensitive to user-dependent gesture patterns, sensor noise characteristics, background environments, and unknown gestures or background motions. To overcome such challenges, we propose a variational autoencoder architecture-based deep metric learning, which is optimized using a novel loss function combining a statistical distance triplet loss and the center loss. By learning the statistical distance between distributions, the proposed solution, compared with triplet loss, is able to better learn the nonlinear characteristics in the data, is less sensitivity to training strategy, and is capable of creating close knit embedding clusters. Moreover, it is experimentally demonstrated that the proposed gesture recognition system using radar spectrograms has improved classification accuracy and random gesture rejection accuracy compared with the state-of-the-art deep metric learning approaches. Furthermore, we proof the real-world capability of the system by implementing a real-time demonstrator, which allows playing “Tetris” with hand gestures.
Heating of tissues in vivo by pulsed focused ultrasound to stimulate enhanced HSP expression (2011)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Tamara Kujawska, Janusz Wójcik, Andrzej Nowicki; Heating of tissues in vivo by pulsed focused ultrasound to stimulate enhanced HSP expression. AIP Conf. Proc. 12 September 2011; 1359 (1): 24–29. https://doi.org/10.1063/1.3607877 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
High-Intensity Focused Ultrasound (Hifu) Treatment For Thyroid Nodules: Experimental And First Clinical Studies (2007)

OBJECTIVE: Thyroid nodules are common and can only be removed by surgery. High‐intensity focused ultrasound (HIFU) could be a possible minimally invasive alternative treatment. The aim of this study was to assess the feasibility of using HIFU to precisely ablate thyroid nodules without affecting neighbouring structures. METHODS: HIFU was generated by a 3‐MHz spherical piezocomposite transducer moved across the target in a stepwise fashion. In a first clinical study 25 patients had their nodules treated with HIFU 2 weeks prior to planned thyroidectomy, using increasing energy. The last patients received a local anesthesia. The lesions were assessed by the pathologist. RESULTS: The histological lesions were clearly visible in most of the fully treated patients, particularly those who received higher energy. Superficial and reversible skin blisters were observed in 7 patients. The design of the treatment head was subsequently modified to eliminate such risk. CONCLUSION: The patient trials confirmed the precision of the targeting and set the energy levels for safe thyroid nodule ablation with HIFU. Further study is needed to assess nodule’s changes at longer follow‐up.
Defibrillator Versus β-Blockers for Unexplained Death in Thailand (DEBUT) (2003)

ICD treatment provides full protection from death related to primary VF in a SUDS population and is superior to beta-blockade treatment.