gebhart/patrepeval huggingface dataset:
Ambipolar Organic Field‐Effect Transistors from Cross‐Conjugated Aromatic Quaterthiophenes; Comparisons with Quinoidal Parent Materials (2009)

Abstract This contribution presents an electrochemical, Raman spectroscopic, and theoretical study probing the differences in molecular and electronic structure of two quinoidal oligothiophenes (3′,4′‐dibutyl‐5,5″‐bis(dicyanomethylene)‐5,5″‐dihydro‐2,2′:5′,2″‐terthiophene and 5,5′‐bis(dicyanomethylene)‐3‐hexyl‐2,5‐dihydro‐4,4′‐dihexyl‐2,2′,5,5′‐tetrahydro‐tetrathiophene) with terminal tetracyanomethylene functionalization and aromatic oligothiophenes where acceptor moieties are positioned at lateral positions along the conjugated chain (6,6′‐dibutylsulfanyl‐[2,2′‐bi‐[4‐dicyanovinylene‐4H‐cyclopenta[2,1‐b:3,4‐b′]dithiophene]). In this way, the consequences of linear and cross conjugation are compared and contrasted. From this analysis, it is apparent that organic field‐effect transistors fabricated with cross‐conjugated tetrathiophene semiconductors should combine the benefits of an electron‐donor aromatic chain with strongly electron‐accepting tetracyanomethylene substituents. The corresponding organic field‐effect transistors exhibit ambipolar transport with rather similar hole and electron mobilities. Moreover, n‐channel conduction is enhanced to yield one of the highest electron mobilities found to date for this type of material.
Magic Angle Spinning NMR and 1H−31P Heteronuclear Statistical Total Correlation Spectroscopy of Intact Human Gut Biopsies (2008)

Previously we have demonstrated the use of 1H magic angle spinning (MAS) NMR spectroscopy for the topographical variations in functional metabolic signatures of intact human intestinal biopsy samples. Here we have analyzed a series of MAS 1H NMR spectra (spin-echo, one-dimensional, and diffusion-edited) and 31P-{1H} spectra and focused on analyzing the enhancement of information recovery by use of the statistical total correlation spectroscopy (STOCSY) method. We have applied a heterospectroscopic cross-examination performed on the same samples and between 1H and 31P-{1H} spectra (heteronuclear STOCSY) to recover latent metabolic information. We show that heterospectroscopic correlation can give new information on the molecular compartmentation of metabolites in intact tissues, including the statistical "isolation" of a phospholipid/triglyceride vesicle pool in intact tissue. The application of 31P-1H HET-STOCSY allowed the cross-assignment of major 31P signals to their equivalent 1H NMR spectra, e.g., for phosphorylcholine and phosphorylethanolamine. We also show pathway correlations, e.g., the ascorbate-glutathione pathway, in the STOCSY analysis of intact tissue spectra. These 31P-1H HET-STOCSY spectra also showed different topographical regions, particular for minor signals in different tissue microenvironments. This approach could be extended to allow the detection of altered distributions within metabolic subcompartments as well as conventional metabonomics concentration-based diagnostics.
An object-based non-blind watermarking that is robust to non-linear geometrical distortion attacks (2009)

This paper presents an object-based non-blind watermarking technique that is robust to non-linear geometrical distortion attacks. This has been one of the most challenging problems for copyright protection of digital content because it is difficult to estimate the distortion parameters for the embedded blocks. In our proposed scheme, the locations used to embed the watermark information are memorized and detected robustly by using relative coordinates with respect to the scale-invariant feature transform (SIFT) feature points. Experimental results with 64-bit watermark embedding demonstrated that the watermark detection performance was improved from 57% to 82% on average, even after nonlinear geometrical attacks such as waving, imploding, swirling, and seam carving.
Ethanol purification by adsorption. Technical quarterly progress report, April 1, 1981-June 30, 1981 (1981)

The technical progress on the purification of ethanol by adsorption on the molecular sieve silicalite is described. The addition of salts has been shown to have a beneficial effect on the ethanol adsorption. The effects of surfactants and trace organics have also been investigated. In the stripping step, the use of microwaves, stripping gases, and displacement gases have been studied.
The Viral Polymerase Inhibitor 7-Deaza-2’-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model (2016)

Zika virus (ZIKV) is an emerging flavivirus typically causing a dengue-like febrile illness, but neurological complications, such as microcephaly in newborns, have potentially been linked to this viral infection. We established a panel of in vitro assays to allow the identification of ZIKV inhibitors and demonstrate that the viral polymerase inhibitor 7-deaza-2'-C-methyladenosine (7DMA) efficiently inhibits replication. Infection of AG129 (IFN-α/β and IFN-γ receptor knock-out) mice with ZIKV resulted in acute neutrophilic encephalitis with viral antigens accumulating in neurons of the brain and spinal cord. Additionally, high levels of viral RNA were detected in the spleen, liver and kidney, and levels of IFN-γ and IL-18 were systematically increased in serum of ZIKV-infected mice. Interestingly, the virus was also detected in testicles of infected mice. In line with its in vitro anti-ZIKV activity, 7DMA reduced viremia and delayed virus-induced morbidity and mortality in infected mice, which also validates this small animal model to assess the in vivo efficacy of novel ZIKV inhibitors. Since AG129 mice can generate an antibody response, and have been used in dengue vaccine studies, the model can also be used to assess the efficacy of ZIKV vaccines. .
Singular YOU WAS/WERE variation and English normative grammars in the eighteenth century (2009)

This article investigates the sociolinguistic processes in singular you was and you were variation in eighteenth-century correspondence. The focus is on the sociolinguistic mechanisms in operation when one variant was established as a standard, high-prestige variant, and the other as a non-standard form. The data are drawn from the Corpus of Early English Correspondence Extension and complemented with evidence from A Representative Corpus of Historical English Registers. The results show that you was peaks before the mid-eighteenth century and gradually becomes a socially stigmatized linguistic marker, as evinced in normative comments in grammars. Men lead the change: the form peaks earlier among men than women who resort to using the were variant longer than men.
ChemInform Abstract: Catalytic CO2 Conversion to Organic Carbonates with Alcohols in Combination with Dehydration System (2014)

Abstract Review: 186 refs.
Antibody-Based Profiling of the Phosphoinositide 3-Kinase Pathway in Clinical Prostate Cancer (2004)

Using both univariate and multivariate analyses, we show that loss of PTEN is highly correlated with the activation of AKT, and this, in turn, is associated with the phosphorylation of S6, one of its main effectors. These three antibodies are potentially able to define a molecular signature of PTEN loss and/or AKT pathway activation in prostate cancer.
Progression from cirrhosis to cancer is associated with early ubiquitin post‐translational modifications: identification of new biomarkers of cirrhosis at risk of malignancy (2014)

Cirrhosis is a lesion at risk of hepatocellular carcinoma (HCC). Identifying mechanisms associated with the transition from cirrhosis to HCC and characterizing biomarkers of cirrhosis at high risk of developing into cancer are crucial for improving early diagnosis and prognosis of HCC. We used MALDI imaging to compare mass spectra obtained from tissue sections of cirrhosis without HCC, cirrhosis with HCC, and HCC, and a top-down proteomics approach to characterize differential biomarkers. We identified a truncated form of monomeric ubiquitin lacking the two C-terminal glycine residues, Ubi(1-74), the level of which increased progressively, from cirrhosis without HCC to cirrhosis with HCC to HCC. We showed that kallikrein-related peptidase 6 (KLK6) catalysed the production of Ubi(1-74) from monomeric ubiquitin. Furthermore, we demonstrated that KLK6 was induced de novo in cirrhosis and increased in HCC in parallel with accumulation of Ubi(1-74). We investigated in vitro the possible consequences of Ubi(1-74) accumulation and demonstrated that Ubi(1-74) interferes with the normal ubiquitination machinery in what is likely to be a kinetic process. Our data suggest that de novo KLK6 expression during early liver carcinogenesis may induce production of Ubi(1-74) by post-translational modification of ubiquitin. Given the deleterious effect of Ubi(1-74) on protein ubiquitination and the major role of ubiquitin machinery in maintenance of cell homeostasis, Ubi(1-74) might severely impact a number of critical cellular functions during transition from cirrhosis to cancer. Ubi(1-74) and KLK6 may serve as markers of cancer risk in patients with cirrhosis.
Direct Inhibition of Retinoblastoma Phosphorylation by Nimbolide Causes Cell-Cycle Arrest and Suppresses Glioblastoma Growth (2013)

Our preclinical findings demonstrate nimbolide as a potent anti-glioma agent that blocks cell cycle and inhibits glioma growth in vitro and in vivo.
Performance of 3D-Database Molecular Docking Studies into Homology Models (2004)

The performance of docking studies into protein active sites constructed by homology model building was investigated using CDK2 and factor VIIa screening data sets. When the sequence identity between model and template near the binding site area is greater than approximately 50%, roughly 5 times more active compounds are identified than would be found randomly. This performance is comparable to docking to crystal structures.
Investigation of radiation trapping in a Cs magneto-optical trap (1997)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation A. Fioretti, J. H. Müller, M. Colla, A. Molisch, M. Allegrini; Investigation of radiation trapping in a Cs magneto-optical trap. AIP Conf. Proc. 5 January 1997; 386 (1): 279–280. https://doi.org/10.1063/1.51861 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
The Effect of Dissolution of Lithium Manganese Oxide Particles on Lithium-Ion Battery Performance (2010)

Abstract not Available.
ICI 164,384, a pure antagonist of estrogen-stimulated MCF-7 cell proliferation and invasiveness. (1989)

Estrogen is known to stimulate the proliferation and basement membrane invasiveness of the MCF-7 human breast cancer cell line. We have compared the new steroidal antiestrogen ICI 164,384, the triphenylethylene 4-hydroxytamoxifen (OHT), and the benzothiophene LY 117018, for their effects on the proliferation and invasiveness of the MCF-7 cell line and its antiestrogen-resistant variant LY-2. While all three antiestrogens blocked the proliferative effects of 17 beta-estradiol on MCF-7 cells, OHT and LY 117018, but not ICI 164,384 stimulated their proliferation in the absence of estrogen. The proliferative effects of OHT and LY 117018 were blocked by ICI 164,384. Basement membrane invasiveness of MCF-7 cells was stimulated by 17 beta-estradiol and OHT, but not LY 117018 or ICI 164,384. Both ICI 164,384 and LY 117018 were able to block the invasiveness induced by either 17 beta-estradiol or OHT. The LY-2 antiestrogen-resistant variant of the MCF-7 cell line showed increased basal proliferation, and responded only slightly to estrogen. ICI 164,384, but not OHT or LY 117018 antagonized the effects of 17 beta-estradiol, but did not reduce proliferation below control levels. The LY-2 line was not resistant to the antiestrogenic effects of LY 117018 or ICI 164,384 on invasiveness, and was stimulated by LY 117018 for this parameter. Thus, ICI 164,384 is a pure antiestrogen for MCF-7 cell proliferation and invasiveness, and may offer clinical advantage over nonsteroidal antiestrogens which can stimulate these activities in tumor models in vitro.
Space Integrating Acousto-Optic Matrix-Matrix Multipliers (1985)

Space integrating pipelined matrix-matrix multipliers using multichannel Bragg cells and parallel output detector arrays are proposed as an appropriate optical implementation of systolic arrays.
781: Time Course of Corporal Vend-Occlusive Dysfunction (CVOD) Development and Inducible Nitric Oxide Synthase (INOS) Expression in Rat Penile Tissue after Cavernosal Nerve Damage (2007)

You have accessJournal of UrologyModerated Poster 23, Monday, May 21, 2007, 10:00 am - 12:00 pm1 Apr 2007781: Time Course of Corporal Vend-Occlusive Dysfunction (CVOD) Development and Inducible Nitric Oxide Synthase (INOS) Expression in Rat Penile Tissue after Cavernosal Nerve Damage Monica G. Ferrini, Istvan Kovanecz, Sandra Sanchez, Jacob Rajfer, and Nestor F. Gonzalez-Cadavid Monica G. FerriniMonica G. Ferrini More articles by this author , Istvan KovaneczIstvan Kovanecz More articles by this author , Sandra SanchezSandra Sanchez More articles by this author , Jacob RajferJacob Rajfer More articles by this author , and Nestor F. Gonzalez-CadavidNestor F. Gonzalez-Cadavid More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)31021-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "781: Time Course of Corporal Vend-Occlusive Dysfunction (CVOD) Development and Inducible Nitric Oxide Synthase (INOS) Expression in Rat Penile Tissue after Cavernosal Nerve Damage." The Journal of Urology, 177(4S), p. 262 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 177Issue 4SApril 2007Page: 262 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Monica G. Ferrini More articles by this author Istvan Kovanecz More articles by this author Sandra Sanchez More articles by this author Jacob Rajfer More articles by this author Nestor F. Gonzalez-Cadavid More articles by this author Expand All Advertisement PDF DownloadLoading ...
VAIS: A dataset for recognizing maritime imagery in the visible and infrared spectrums (2015)

The development of fully autonomous seafaring vessels has enormous implications to the world's global supply chain and militaries. To obey international marine traffic regulations, these vessels must be equipped with machine vision systems that can classify other ships nearby during the day and night. In this paper, we address this problem by introducing VAIS, the world's first publicly available dataset of paired visible and infrared ship imagery. This dataset contains more than 1,000 paired RGB and infrared images among six ship categories - merchant, sailing, passenger, medium, tug, and small - which are salient for control and following maritime traffic regulations. We provide baseline results on this dataset using two off-the-shelf algorithms: gnostic fields and deep convolutional neural networks. Using these classifiers, we are able to achieve 87.4% mean per-class recognition accuracy during the day and 61.0% at night.
An Application of Model Predictive Control to Reactive Motion Planning of Robot Manipulators (2021)

In recent years, a number of trajectory optimization algorithms have been proposed and established for motion planning of robot manipulators in complex, but static, predefined environments. To enable reactive motion planning under uncertain conditions caused, for example, by moving obstacles, this paper proposes a formulation of the trajectory optimization problem that is tailored for model predictive control. The proposed algorithmic solution leverages off-the-shelf computational tools for nonlinear model predictive control, optimization, and collision checking. In addition, a motion planning paradigm is introduced to allow for online collision-free motion when following a joystick command. The approach is validated in the context of an industrial pick-and-place application using MATLAB® and a Kinova® robot manipulator, both in simulation and with actual hardware.
Analysis of a rate-based access control mechanism for high-speed networks (1993)

The authors present an analysis of a rate-based access control mechanism for high-speed networks that is based on the buffered leaky bucket scheme. The analysis assumes a discrete time environment representative of asynchronous transfer mode (ATM) networks and a batch arrival process that captures cell arrivals generated by segmentation of large user packets or superposition of a number of arrival streams. The solution method is based on matrix analytic techniques, but the particular structure of the system allowed for a number of important improvements. It is shown that the problem can be partitioned and that the matrix G, central to the matrix analytic technique, can be computed using exact recursive procedures instead of the traditional iterative approach. These improvements not only extend the range of systems that can be handled, but also eliminate computational issues such as convergence rate and stopping criterion.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Location Tracking with Directional Antennas in Wireless Sensor Networks (2005)

In this paper, we investigate the use of multiple directional antennas on sensor motes for location determination and mobile node monitoring. One key aspect that distinguishes wireless sensor networks is inexpensive transmitters and receivers that still maintain acceptable connectivity. Therefore, complex RF solutions are often not applicable. We propose and demonstrate a location estimation algorithm on a single sensor node equipped with inexpensive directional antennas by measuring the received signal strength of the transmission peers. This algorithm is further applied to the dynamic tracking of a wandering mote. The location tracking error can be reduced from 300% to 16% by using moving average schemes and merging estimates from different sets of antennas. The mean error of tracking estimates can be obtained to provide the certainty of location tracking. Therefore, only a single mote with angular diverse multiple antennas is needed to determine the location of a mote without triangulation.
VIDEO CAMERAS FOR ROADWAY SURVEILLANCE: TECHNOLOGY REVIEW, TEST METHODS, AND RESULTS (1993)

Effective implementation of advanced traffic management strategies depends on timely, reliable, and comprehensive information on traffic conditions. Closed circuit television surveillance of the roadway network is believed to be one of the best mechanisms for providing this information to a traffic operation center. This work supports the application of video surveillance technologies to roadway traffic monitoring. The current state of the art in surveillance camera technology is reviewed. Technical considerations relevant to the selection of video cameras for traffic surveillance applications are summarized. Applicable standards are identified, and evaluation criteria and test procedures are described. A total of 32 commercially available monochrome and color video cameras are evaluated with respect to these criteria. General considerations and specific test results are reported.
Urodynamic Study in Patients with Myelitis (2003)

Background: Voiding disturbance is one of the frequent symptoms of myelitis. Clinical manifestations of urinary dis-turbance in the patients with myelitis are results of the specific neurological lesion of the spinal cord, but can be varied. To determine the relationship between the neurological spinal cord level and bladder dysfunction, we analyzed the uro-dynamic studies of patients with myelitis who complained of urinary symptoms. Methods: We investigated the urody-namic study in 30 patients with myelitis with urinary symptoms. Neurological examination and spinal MR imaging determined the clinical and radiological spinal cord levels. Urodynamic findings were classified as detrusor hyperreflex-ia (DH), detrusor-external sphincter dyssynergia (DSD), detrusor areflexia/hyporeflexia (DA) or normal. We analyzed the correlation between the neurological spinal level and urodynamic findings. R e s u l t s: Among the 30 patients, 14
Design of a Bifunctional Ir–Zr Based Metal–Organic Framework Heterogeneous Catalyst for the N‐Alkylation of Amines with Alcohols (2014)

Abstract The direct N‐alkylation of amines with alcohols was performed with an Ir‐Zr‐based metal–organic framework multifunctional heterogeneous catalyst. This system is efficient and environmentally benign for the synthesis of various organic amines in air in the absence of a base. The catalyst was recovered and reused without significant loss of activity, and only water was produced as a byproduct.
Whole‐Transcriptome Amplification of Single Cells for Next‐Generation Sequencing (2015)

Single-cell transcriptome analysis gives insight into the heterogeneity of neighboring cells in tissues or cell cultures. It has been shown that the variability of cells is important for biological function. However, cell variability can be an indication of disease (e.g., cancer). In order to elucidate cell variability in health and disease, single-cell transcriptomes can be analyzed by new next-generation sequencing (NGS) platforms. NGS analysis currently requires a few hundred nanograms of RNA. Consequently, accurate whole-transcriptome amplification is required to analyze the transcriptome of a single cell by NGS. This unit describes the entire workflow from cells to NGS, including cell quality testing, cell lysis, gDNA removal, whole-transcriptome amplification, and NGS library preparation. Recommendations for WTA quality control are given and optional protocols for using purified RNA for WTA and WTA purification are described.
Optical performance monitoring using asynchronous amplitude histogram (2007)

We report on the state of development of optical performance monitoring (OPM) method based on asynchronous amplitude histogram analysis. Accurate monitoring of noise and chromatic dispersion is demonstrated for intensity- and phase-modulated signals.
DNA damage response curtails detrimental replication stress and chromosomal instability induced by the dietary carcinogen PhIP (2016)

PhIP is an abundant heterocyclic aromatic amine (HCA) and important dietary carcinogen. Following metabolic activation, PhIP causes bulky DNA lesions at the C8-position of guanine. Although C8-PhIP-dG adducts are mutagenic, their interference with the DNA replication machinery and the elicited DNA damage response (DDR) have not yet been studied. Here, we analyzed PhIP-triggered replicative stress and elucidated the role of the apical DDR kinases ATR, ATM and DNA-PK<sub>cs</sub> in the cellular defense response. First, we demonstrate that PhIP induced C8-PhIP-dG adducts and DNA strand breaks. This stimulated ATR-CHK1 signaling, phosphorylation of histone 2AX and the formation of RPA foci. In proliferating cells, PhIP treatment increased the frequency of stalled replication forks and reduced fork speed. Inhibition of ATR in the presence of PhIP-induced DNA damage strongly promoted the formation of DNA double-strand breaks, activation of the ATM-CHK2 pathway and hyperphosphorylation of RPA. The abrogation of ATR signaling potentiated the cell death response and enhanced chromosomal aberrations after PhIP treatment, while ATM and DNA-PK inhibition had only marginal effects. These results strongly support the notion that ATR plays a key role in the defense against cancer formation induced by PhIP and related HCAs.