gebhart/patrepeval huggingface dataset:
Measuring the Emissions of Passing Cars (1996)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMeasuring the Emissions of Passing CarsG. A. Bishop and D. H. StedmanView Author Information Department of Chemistry and Biochemistry, University of Denver, Denver, Colorado 80208 Cite this: Acc. Chem. Res. 1996, 29, 10, 489–495Publication Date (Web):October 10, 1996Publication History Received6 March 1996Published online10 October 1996Published inissue 10 October 1996https://pubs.acs.org/doi/10.1021/ar950240xhttps://doi.org/10.1021/ar950240xresearch-articleACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views1151Altmetric-Citations104LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Atmospheric chemistry,Byproducts,Fossil fuels,Mathematical methods,Redox reactions Get e-Alerts
Strain-Engineered Biaxial Tensile Epitaxial Germanium for High-Performance Ge/InGaAs Tunnel Field-Effect Transistors (2015)

The structural, morphological, and energy band alignment properties of biaxial tensile-strained germanium epilayers, grown in-situ on GaAs via a linearly graded In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> Ga <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1-x</sub> As buffer architecture and utilizing dual chamber molecular beam epitaxy, were investigated. Precise control over the growth conditions yielded a tunable in-plane biaxial tensile strain within the Ge thin films that was modulated by the underlying In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> Ga <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1-x</sub> As “virtual substrate” composition. In-plane tensile strains up to 1.94% were achieved without Ge relaxation for layer thicknesses of 15 to 30 nm. High-resolution x-ray diffraction supported the pseudomorphic nature of the Ge/In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> Ga <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1-x</sub> As interface, indicating a quasi-ideal stress transfer to the Ge lattice. High-resolution transmission electron microscopy revealed defect-free Ge epitaxy and a sharp, coherent interface at the Ge/In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> Ga <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1-x</sub> As heterojunction. Surface morphology characterization using atomic force microscopy exhibited symmetric, 2-D cross-hatch patterns with root mean square roughness less than 4.5 nm. X-ray photoelectron spectroscopic analysis revealed a positive, monotonic trend in band offsets for increasing tensile strain. The superior structural and band alignment properties of strain-engineered epitaxial Ge suggest that tensile-strained Ge/In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> Ga <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1-x</sub> As heterostructures show great potential for future high-performance tunnel field-effect transistor architectures requiring flexible device design criteria while maintaining low power, energy-efficient device operation.
Reduction of ohmic contact resistance of AlGaN/GaN HFETs by doping of thermally diffused Si (2004)

Low ohmic contact resistance is crucial to realization of good RF and power performances of AlGaN/GaN heterojunction field effect transistors (HFETs). However, with almost universal use of Ti/Al based electrode, usual specific contact resistance (pc) remains only at 1 /spl times/ 10/sup -5/ /spl Omega//spl middot/cm level which is insufficient for the ultimate goal of exceeding the performances of the GaAs based FETs. Therefore, in order to overcome the very high potential barrier of AlGaN, a more aggressive method is required. In this work, we report on a simple but very effective method to reduce the contact resistance by thermal diffusion of Si dopants selectively into the area underneath the contact electrodes. By diffusing Si from the AlGaN surface at 1000/spl deg/C for 30 minutes, a record low /spl rho//sub c/ of 1.2 /spl times/ 10/sup -6/ /spl Omega//spl middot/cm/sup 2/ is realized.
New Mechanistic Proposal for Some Heptamolybdate‐Ion‐Catalyzed Isomerizations (1987)

Abstract Heptamolybdate‐ion(HM)‐catalyzed C(2) epimerization of D‐glucose and racemization of D‐glyceraldehyde proceed with comparable rates and activation parameters; HM catalyzes the isomerization of glucal and galactal triacetates as well. For all of the above transformations, a common, new mechanism is proposed that invokes stabilization of 3‐oxa‐allylic cation species by the central Mo(VI) atom.
The Radical-Binding Lipocalin A1M Binds to a Complex I Subunit and Protects Mitochondrial Structure and Function (2012)

A1M binds to a subunit of Complex I and has a role in assisting the mitochondria to maintain its energy delivery during cell death. A1M may also, at the same time, counteract and eliminate the ROS generated by the mitochondrial respiration to prevent oxidative damage to surrounding healthy tissue.
Single-Layer InAs Quantum Dots for High-Performance Planar Photodetectors Near 1.3 $\mu\hbox{m}$ (2010)

The potential of InAs quantum-dot (QD) photodetectors for room-temperature high-speed operation at wavelengths near 1.3 μm is evaluated. Specifically, planar metal-semiconductor-metal structures on GaAs substrates containing one absorption layer of self-assembled InAs QDs embedded in Ga(In)As matrices are fabricated, characterized, and analyzed. Light absorption, optically generated carrier transport, and collection mechanisms are studied. The role of the QD embedding matrix in the lateral transport of the photogenerated carriers is also studied by comparing structures with QDs in GaAs and In <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.15</sub> Ga <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.85</sub> As matrices. Devices show low dark currents in tens of nanoamperes and high light sensitivity when adjusted to QD volumes, whereas external quantum efficiency remains in the range 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-5</sup> -10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-4</sup> for all fabricated samples. The time response of the fabricated devices is obtained using an excitation wavelength resonant with QD interband transitions, thus allowing the photogeneration of electron-hole pairs inside the dots. Results prove detection capability of a single layer of QDs in a common photodetector structure with a full-width half-maximum time response on the order of 10 ps. A long tail, about 100 ps, but at a small fraction of the peak response amplitude, is also observed, suggesting mechanisms for charge transport and collection.
Metal–Organic Conjugated Microporous Polymers (2010)

Zwei vielseitige Strategien für die Herstellung von Metall-organischen konjugierten mikroporösen Polymeren (MO-CMPs) mit Metallen wie Rhenium, Rhodium und Iridium werden beschrieben (siehe Beispiel). Diese Materialien vereinen in sich zwei Merkmale: eine ausgedehnte, unterbrechungsfreie elektronische Konjugation und das Vorhandensein katalytisch aktiver Metallzentren. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Experimental and theoretical thermal analysis of a Hybrid Silicon Evanescent Laser (2007)

In this work we present both experimental and theoretical thermal analysis of an electrically pumped hybrid silicon evanescent laser. Measurements of an 850 mum long Fabry-Perot structure show an overall characteristic temperature of 51 oC, an above threshold characteristic temperature of 100 oC, and a thermal impedance of 41.8 oC/W. Finite element analysis of the laser structure predicts a thermal impedance of 43.5 oC/W, which is within 5% of the experimental results. Using the overall characteristic temperature, above threshold characteristic temperature, and the measured thermal impedance, the continuous wave output power vs. current from the laser is simulated and is in good agreement with experiment.
Suppl. Movie 1 from LIM Kinase Inhibitor Pyr1 Reduces the Growth and Metastatic Load of Breast Cancers (2023)

&lt;p&gt;FRAP analysis of actin dynamics in invadopodia treated with vehicle or Pyr1&lt;/p&gt;
A Variable Step-Size Blind Equalization Algorithm Based on Particle Swarm Optimization (2018)

In this work, a variable step-size (VSS) blind equalization algorithm is presented for a multimodulus blind equalization scheme. The parameters of the proposed algorithm are selected using a particle swarm optimization strategy. Eventually, the best parameters for the proposed VSS blind equalization algorithm are obtained and better performance is obtained when compared to the trial-and-error method for choosing these parameters. Ultimately, a considerable reduction in computational complexity when compared to the fixed-step algorithm with extra constraints. Simulation results support this new proposed technique.
Rap1 and its effector KRIT1/CCM1 regulate β-catenin signaling (2010)

KRIT1, also called CCM1, is a member of a multiprotein complex that contains the products of the CCM2 and PDCD10 (also known as CCM3 ) loci. Heterozygous loss of any of the genes that encode these proteins leads to cerebral cavernous malformations (CCM), which are vascular lesions that are found in around 0.5% of humans. KRIT1 mediates the stabilization of β-catenin-containing endothelial cell-cell junctions downstream of the Rap1 GTPase. Here, we report that Rap1 and KRIT1 are negative regulators of canonical β-catenin signaling in mice and that hemizygous Krit1 deficiency exacerbates β-catenin-driven pathologies. Depletion of endothelial KRIT1 caused β-catenin to dissociate from vascular endothelial (VE)-cadherin and to accumulate in the nucleus with consequent increases in β-catenin-dependent transcription. Activation of Rap1 inhibited β-catenin-dependent transcription in confluent endothelial cells; this effect required the presence of intact cell-cell junctions and KRIT1. These effects of KRIT1 were not limited to endothelial cells; the KRIT1 protein was expressed widely and its depletion increased β-catenin signaling in epithelial cells. Moreover, a reduction in KRIT1 expression also increased β-catenin signaling in vivo. Hemizygous deficiency of Krit1 resulted in a ~1.5-fold increase in intestinal polyps in the ApcMin/+ mouse, which was associated with increased β-catenin-driven transcription. Thus, KRIT1 regulates β-catenin signaling, and Krit1+/− mice are more susceptible to β-catenin-driven intestinal adenomas.
Sonochemical Preparation and Characterization of Eu2O3 and Tb2O3 Doped in and Coated on Silica and Alumina Nanoparticles (1999)

Submicron size spheres of silica and alumina prepared by well-known methods were coated sonochemically by nanoparticles of oxides of europium and terbium using the same concentration of ions. We have also used sonochemistry to prepare nanoparticles of silica and alumina doped by the same rare-earth ions for comparison. The highest luminescence intensities were observed for europium and terbium doped in nanoparticles of alumina of dimension 20−30 nm. The intensities are comparative or higher than in commercial phosphors.
Romk1 Knockout Mice Do Not Produce Bartter Phenotype but Exhibit Impaired K Excretion (2016)

Romk knock-out mice show a similar phenotype to Bartter syndrome of salt wasting and dehydration due to reduced Na-K-2Cl-cotransporter activity. At least three ROMK isoforms have been identified in the kidney; however, unique functions of any of the isoforms in nephron segments are still poorly understood. We have generated a mouse deficient only in Romk1 by selective deletion of the Romk1-specific first exon using an ES cell Cre-LoxP strategy and examined the renal phenotypes, ion transporter expression, ROMK channel activity, and localization under normal and high K intake. Unlike Romk(-/-) mice, there was no Bartter phenotype with reduced NKCC2 activity and increased NCC expression in Romk1(-/-) mice. The small conductance K channel (SK) activity showed no difference of channel properties or gating in the collecting tubule between Romk1(+/+) and Romk1(-/-) mice. High K intake increased SK channel number per patch and increased the ROMK channel intensity in the apical membrane of the collecting tubule in Romk1(+/+), but such regulation by high K intake was diminished with significant hyperkalemia in Romk1(-/-) mice. We conclude that 1) animal knockouts of ROMK1 do not produce Bartter phenotype. 2) There is no functional linking of ROMK1 and NKCC2 in the TAL. 3) ROMK1 is critical in response to high K intake-stimulated K(+) secretion in the collecting tubule.
ChemInform Abstract: Metal‐Free Aerobic Oxidations Mediated by N‐Hydroxyphthalimide. A Concise Review (2014)

Abstract Review: 73 refs.
Energy losses in a boundary layer of an acoustical resonator (1998)

A one-dimensional model of nonlinear standing waves in an oscillating closed cavity has been developed and was presented at previous meetings. The present study focuses on an investigation of energy losses in the boundary layer and on the effect of the boundary layer on the acoustic field in the resonator. The boundary layer dissipation is much greater than the dissipation caused by volume attenuation. The fluid motion in the boundary layer is considered in a linear approximation. The boundary layer model is coupled with the one-dimensional model for the acoustics in the volume of the resonator. An interaction term which represents the flow from the boundary layer to the volume of the resonator is added to the mass conservation equation. A new modified one-dimensional equation that takes into account the flow from the boundary layer is obtained. Waveforms and harmonic amplitudes of pressure and velocity are calculated along the resonator axis with the modified model. The dissipation in the boundary layer and Q-factor of the resonator are also calculated. Results are presented for three geometries, i.e., a cone, a horn-cone, and a bulb.
Fischer–Tropsch Synthesis over a Cobalt Catalyst Supported on Titania-Doped Silicon Carbide (2020)

A cobalt Fischer–Tropsch synthesis catalyst supported on titania-doped silicon carbide is synthesized and comprehensively studied by a number of physicochemical means. The dynamics of the behavior and deactivation of the catalyst was studied after its stable operation for 1500 h during continuous experimental resource testing with a periodic change in the syngas flow rate and pressure and the process temperature. This catalyst has two types of active sites, on which products with different Schulz–Flory distribution parameters form. Depending on the process regime, the effective formation of soft waxes or more high-molecular-weight products is possible.
Humans and Machines can be Jointly Spatially Multiplexed by Massive MIMO (2018)

Future cellular networks are expected to support new communication paradigms such as machine-type communication (MTC) services along with conventional human-type communication (HTC) services. This requires base stations to serve a large number of devices in relatively short channel coherence intervals, which renders allocation of orthogonal pilot sequences per-device in each cell impractical. Furthermore, the stringent power constraints, place-and-play type connectivity and various data rate requirements of MTC devices make it impossible for the traditional cellular architecture to accommodate MTC and HTC services together. Massive multiple-input-multiple-output (mMIMO) technology has the potential to allow the coexistence of HTC and MTC services, thanks to its inherent spatial multiplexing properties and low transmission power requirements. In this work, we first tackle the optimal non-orthogonal pilot design problem and demonstrate that the optimal pilot sequences are Welch bound equality sequences. In the second part, we investigate the performance of a single cell under a shared physical channel assumption for MTC and HTC services and propose a novel scheme for sharing the time-frequency resources. The analysis reveals that mMIMO can significantly enhance the performance of such a setup and allow the inclusion of MTC services into the cellular networks without requiring additional resources.
Bioengineered human acellular vessels recellularize and evolve into living blood vessels after human implantation (2019)

Traditional vascular grafts constructed from synthetic polymers or cadaveric human or animal tissues support the clinical need for readily available blood vessels, but often come with associated risks. Histopathological evaluation of these materials has shown adverse host cellular reactions and/or mechanical degradation due to insufficient or inappropriate matrix remodeling. We developed an investigational bioengineered human acellular vessel (HAV), which is currently being studied as a hemodialysis conduit in patients with end-stage renal disease. In rare cases, small samples of HAV were recovered during routine surgical interventions and used to examine the temporal and spatial pattern of the host cell response to the HAV after implantation, from 16 to 200 weeks. We observed a substantial influx of alpha smooth muscle actin (αSMA)-expressing cells into the HAV that progressively matured and circumferentially aligned in the HAV wall. These cells were supported by microvasculature initially formed by CD34<sup>+</sup>/CD31<sup>+</sup> cells in the neoadventitia and later maintained by CD34<sup>-</sup>/CD31<sup>+</sup> endothelial cells in the media and lumen of the HAV. Nestin<sup>+</sup> progenitor cells differentiated into either αSMA<sup>+</sup> or CD31<sup>+</sup> cells and may contribute to early recellularization and self-repair of the HAV. A mesenchymal stem cell-like CD90<sup>+</sup> progenitor cell population increased in number with duration of implantation. Our results suggest that host myogenic, endothelial, and progenitor cell repopulation of HAVs transforms these previously acellular vessels into functional multilayered living tissues that maintain blood transport and exhibit self-healing after cannulation injury, effectively rendering these vessels like the patient's own blood vessel.
Antagonism and selective modulation of the human glucocorticoid receptor both reduce recruitment of p300/CBP and the Mediator complex (2023)

Abstract Exogenous glucocorticoids are frequently used to treat inflammatory disorders and as adjuncts for treatment of solid cancers. However, their use is associated with severe side effects and therapy resistance. Novel glucocorticoid receptor (GR) ligands with a patient-validated reduced side effect profile have not yet reached the clinic. GR is a member of the nuclear receptor family of transcription factors and heavily relies on interactions with coregulator proteins for its transcriptional activity. To elucidate the role of the GR interactome in the differential transcriptional activity of GR following treatment with agonists, antagonists, or lead selective GR agonists and modulators (SEGRAMs), we generated comprehensive interactome maps by high-confidence proximity proteomics in lung epithelial carcinoma cells. We found that the GR antagonist RU486 and the SEGRAM Dagrocorat both reduced GR interaction with CREB-binding protein (CBP)/p300 and the Mediator complex when compared to the full GR agonist Dexamethasone. Our data offer new insights into the role of differential coregulator recruitment in shaping ligand-specific GR-mediated transcriptional responses. In Brief Glucocorticoids are commonly prescribed for the treatment of inflammatory disorders but are associated with severe side effects. Novel glucocorticoid receptor (GR) ligands with strong anti-inflammatory effects but reduced side effects are still sought after. Despite decades-long GR research, there is still an incomplete understanding of the molecular mechanisms driving context-specific GR activity. Using proximity labeling proteomics, we identified CREB-binding protein (CBP), p300 and the Mediator complex as potential crucial GR coregulators driving ligand-induced changes in GR’s transcriptional activity. Highlights Glucocorticoids (GCs), potent anti-inflammatory agents, can elicit side effects More selective GCs, causing less side effects, are currently still unavailable Lack of fundamental insights on context-specific actions of the GC receptor (GR) We mapped ligand-specific GR interactomes using proximity labeling proteomics p300/CBP and Mediator undergo ligand-dependent changes in interaction with GR
Turkestan Cockroaches Avoid Entering a Static Electric Field upon Perceiving an Attractive Force Applied to Antennae Inserted into the Field (2021)

This study analysed the mechanism of avoidance behaviour by adult Turkestan cockroaches (<i>Shelfordella lateralis</i> Walker) in response to a static electric field (S-EF) formed in the space between a negatively charged polyvinyl chloride-insulated iron plate (N-PIP) and a grounded metal net (G-MN). The negative surface charge supplied to the iron plate by a voltage generator caused the G-MN to polarise positively via electrostatic induction. In the S-EF, the negative charge of the N-PIP created a repulsive force that pushed free electrons in the field toward the ground via the G-MN. When insects released in the space surrounded by the S-EF inserted their antennae into the S-EF, they pulled them back reflexively and moved backward. The analysis indicated that an electric current flowed transiently toward the ground when an insect inserted its antennae into the S-EF. The insect became positively charged via this discharge and was attracted to the opposite pole (N-PIP). In response to this attractive force, the insect pulled its antennae back quickly. The positive electrification caused by the removal of free electrons from the antenna tip triggered the avoidance behaviour.