gebhart/patrepeval huggingface dataset:
On the Scaled Inverse of $(x^i-x^j)$ modulo Cyclotomic Polynomial of the form $\Phi_{p^s}(x)$ or $\Phi_{p^s q^t}(x)$ (2021)

The scaled inverse of a nonzero element $a(x)\in \mathbb{Z}[x]/f(x)$, where $f(x)$ is an irreducible polynomial over $\mathbb{Z}$, is the element $b(x)\in \mathbb{Z}[x]/f(x)$ such that $a(x)b(x)=c \pmod{f(x)}$ for the smallest possible positive integer scale $c$. In this paper, we investigate the scaled inverse of $(x^i-x^j)$ modulo cyclotomic polynomial of the form $\Phi_{p^s}(x)$ or $\Phi_{p^s q^t}(x)$, where $p, q$ are primes with $p<q$ and $s, t$ are positive integers. Our main results are that the coefficient size of the scaled inverse of $(x^i-x^j)$ is bounded by $p-1$ with the scale $p$ modulo $\Phi_{p^s}(x)$, and is bounded by $q-1$ with the scale not greater than $q$ modulo $\Phi_{p^s q^t}(x)$. Previously, the analogous result on cyclotomic polynomials of the form $\Phi_{2^n}(x)$ gave rise to many lattice-based cryptosystems, especially, zero-knowledge proofs. Our result provides more flexible choice of cyclotomic polynomials in such cryptosystems. Along the way of proving the theorems, we also prove several properties of $\{x^k\}_{k\in\mathbb{Z}}$ in $\mathbb{Z}[x]/\Phi_{pq}(x)$ which might be of independent interest.
Evaluation of the potential of phase-contrast computed tomography for improved visualization of cancerous human liver tissue (2013)

Grating-based PCCT significantly improves the soft-tissue contrast in ex-vivo liver specimens and holds the potential to overcome the need of contrast materials for visualization of the tumor vascularization.
Vehicle Lateral Velocity and Yaw Rate Control With Two Independent Control Inputs (1992)

In automatic lateral control, which will play a key role in highway automation, vehicles must follow a given path and vehicle direction must be controlled as desired. Therefore, the ideal is for the lateral motion and yaw motion of the vehicle to be controlled independently. This requires at least one additional control input which is independent of the front steering angle. This paper explores the use of two independent control inputs, which are the front steering angle and an extra control input. Three types of extra control inputs are considered: (1) a differential driving torque between the two front wheels; (2) that between the two rear wheels; and (3) the rear steering angle. The analysis utilizing a linearized vehicle model shows that the front and rear independent steering allows a wider variation of lateral velocity and yaw rate in the steady state. A control algorithm with front and rear independent steering, which features continuously changing gains dependent on vehicle velocity and road conditions, is presented. Performance evaluation is based on a simulation study on a nonlinear vehicle model and an experimental study with a laboratory model vehicle.
ChemInform Abstract: Catalytic Enantioselective Reductive Desymmetrization of Achiral and meso Compounds (2013)

Abstract Review: 93 refs.
Enumeration of integer projections of parametric polytopes (2004)

Although Barvinok’s algorithm for counting lattice points in a rational polytope easily extends to linearly parametrized polytopes, it is not immediately obvious whether the same applies to Barvinok and Woods ’ algorithm for counting the number of points in the integer projection of a polytope. We therefore propose a heuristics based technique that directly manipulates the parametric polytope, reducing it by either eliminating variables, slicing the polyhedron in the combined data and parameter space along a line or ray, or splitting the problem into several smaller subproblems.
Applied research on the conduct of surveys of adolescent health behaviors and characteristics (1991)

http://babel.hathitrust.org/cgi/pt?id=mdp.39015071887199;view=2up;ui=fullscreen#page/n0/mode/2up
Novel Synthesis and Properties of Smart Core‐Shell Microgels (2005)

Abstract A new method has been developed to prepare smart microgels that consist of well‐defined temperature‐sensitive cores with pH‐sensitive shells. The microgels were obtained directly from aqueous graft copolymerization of N ‐isopropylacrylamide and N , N ′‐methylenebisacrylamide from water‐soluble polymers containing amino groups such as poly(ethyleneimine) and chitosan. The gel diameters ranged from 300 to 400 nm with narrow size distribution. The unique core‐shell nanostructures exhibited tuneable responses to pH and temperature.
Mir-15a/16-1 Cluster Is Frequently Deleted In Primary Hodgkin Lymphoma and Modulates Multiple Survival Pathways Including AP-1 (2010)

Abstract Abstract 746 Classical Hodgkin Lymphoma (cHL) Reed-Sternberg (RS) cells have crippling mutations of their rearranged Ig genes and lack B-cell receptor-mediated survival signals. As a consequence, cHLs rely on alternative survival and proliferation pathways including AP-1. Although cHL RS cells express high levels of the AP-1 components, cJun and JunB, and depend on AP-1-mediated proliferation signals, the mechanism of constitutive AP-1 activation in cHL remains undefined. In a screen for genetic abnormalities in cHL, we integrated microRNA (miR) expression profiles with high resolution copy number data and identified single copy loss of the miR-15a/16-1 locus (chromosome 13q14) and decreased miR-15a/16 expression in 75% of examined HL cell lines. We isolated primary Hodgkin RS cells using laser-capture microdissection and confirmed frequent single copy loss of the miR-15a/16-1 locus by quantitative PCR and associated decreased miR-15a/16 abundance by RT-PCR in 10/23 (43%) of primary tumors. Using retroviral vectors containing miR-15a and miR-16, we reconstituted miR-15a/16 expression in HL cell lines with single copy loss of chromosome 13q14. In these HL lines, miR-15a/16 reconstitution was associated with cell cycle arrest, significantly decreased cellular proliferation and induction of apoptosis (88% apoptotic cells at 48 hours). In addition, miR-15a/16 reconstitution resulted in significant downregulation of multiple survival pathway components and known miR-15a/16 targets including panAKT, BCL2 and cyclin D1. Using a stand-alone miRanda algorithm with direct sequence entry, we also identified a candidate miR-15a/16 binding site in the AP-1 component, cJun. In multiple HL cell lines, miR-15a/16 reconstitution decreased the expression of cJun and additional known AP-1 targets such as galectin-1. Therefore, miR-15a/16-1 deletion is a frequent genetic abnormality in HL cell lines and primary tumors, a candidate mechanism of AP-1 activation in HL and a modulator of multiple critical survival pathways in this disease. Disclosures: No relevant conflicts of interest to declare.
THE SEPARATION OF PEPTIDE HORMONE DIASTEREOISOMERS BY REVERSE PHASE HIGH PRESSURE LIQUID CHROMATOGRAPHY (1979)

Experimental conditions and parameters involved in high performance liquid chromatography (HPLC) separations of the peptide hormone oxytocin and seven of its diastereoisomers, namely [1‐hemi‐ d ‐cystine]‐, [2‐ d ‐tyrosine]‐, [4‐ d ‐glutamine]‐, [5‐ d ‐asparagine]‐, [6‐hemi‐ d ‐cystine‐], [7‐ d ‐proline]‐, and [8‐ d ‐leucine]‐oxytocin, on reverse phase columns were investigated. The effects of solvent, pH, and salt concentration were studied. Using the solvent systems 10% tetrahydrofuran‐ammonium acetate buffer or 18% acetonitrile‐ammonium acetate buffer and the üBondapak C 18 support, oxytocin was separated from each of its diastereoisomers under all conditions studied, but the order of elution of diastereoisomers was highly dependent on solvent and to a lesser extent on pH. Separations of the hormone and its diastereoisomers on reverse phase HPLC and on classical partition chromatography on Sephadex G‐25 were compared. The results are discussed in terms of the interactions of the solute with the reverse phase column and the solvent system. Implications of these findings in terms of the different solution conformations of the peptides are discussed.
An Ultra-compact Nanophotonic Optical Modulator using Multi-State Topological Optimization (2017)

Optical modulators are one of the most important elements of photonic circuits. Here, we designed, fabricated and characterized a nanophotonic all optical modulator (NOM) in silicon that is an order of magnitude smaller than any previous silicon modulators, and exhibits an extinction ratio and operable spectrum that are an order of magnitude larger than alternatives. Simulations indicate that our device can provide about 9.5dB extinction ratio with a bandwidth of 10nm, centered at 1.55um, corresponding to extinction ratio per device length of about 3.2dB/μm. Our device is fully compatible with standard complementary metal-oxide-semiconductor (CMOS) fabrication processes. The device is an example of a photonic device designed using multi-state topological optimization and will lead to a new class of ultra-compact and multi-functional active integrated-silicon devices.
Tdap vaccination in pregnancy (2021)

A Canadian study of children (< 17 yr) who were hospitalized for pertusis from 1999–2015 found that infants younger than 2 months had the highest incidence of admission to hospital (116.40, 95% confidence interval [CI] 85.32–147.49 per 100 000 population) and to the intensive care unit (33.48,
ChemInform Abstract: 8‐THP‐DHI Analogues as Potent Type I Dual TIE‐2/VEGF‐R2 Receptor Tyrosine Kinase Inhibitors. (2010)

Abstract A series of 17 title compounds of type (I) are prepared by conventional procedures.
Empirical evaluation of excluded middle vantage point forest on biological sequences workload (2011)

We develop and evaluate a version of the excluded middle vantage point forest in support of range searches and load balancing for parallel queries. The algorithm is evaluated using a benchmark suite that includes real-world biological sequence workloads. Favorable results are demonstrated when comparing to the Multiple Vantage Point Tree and Spatial Approximation Tree algorithms with respect to sequential measures. We also demonstrate that the performance of this approach scales linearly up to at least 128 cores and outperforms a naive distributed multiple vantage point forest approach when run in parallel.
Intramolecular charge separation in a hydrogen bonded tyrosine–ruthenium(ii)–naphthalene diimide triad (2004)

Long-lived charge-separated states in the ns to [micro sign]s range were observed upon laser flash excitation of a donor-chromophore-acceptor triad based on tris(bipyridine) ruthenium(ii) as photo-sensitizer, naphthalene diimide as acceptor, and a hydrogen bonded phenol as donor.
LSI Design for Sensing Data Transmission by Interruption in Tactile Sensor Systems (2009)

This paper proposes a novel tactile sensor system, which acquires sensing data by interrupt data transmission from each tactile sensor element. The interrupt makes decentralized sensing data transmission. Compared with existing centralized tactile sensor systems, the system can handle a large amount of tactile sensor elements and attach the elements on the arbitrary surface of the robot, because decentralized serial bus communication and the integration of a MEMS sensor and a signal processing LSI realize low power consumption, high speed response and flexible network morphology. In this paper, we focus on system analysis and LSI design for the system. Experimental results show that response time and power consumption of a tactile sensor element, which is composed of a MEMS capacitive force sensor and a signal processing LSI, are 21μs and 2mW, respectively. The computational experiments proved that more than thousands of the elements can be mounted in the system.
PT Symmetry Induced Rings of Lasing Threshold Modes Embedded with Discrete Bound States in the Continuum (2021)

It is well known that spatial symmetry in a photonic crystal (PhC) slab is capable of creating bound states in the continuum (BICs), which can be characterized by topological charges of polarization vortices. Here, we show that when a PT-symmetric perturbation is introduced into the PhC slab, a new type of BICs ( pt -BICs) will arise from each ordinary BIC together with the creation of rings of lasing threshold modes with pt -BICs embedded in these rings. Different from ordinary BICs, the Q -factor divergence rate of a pt -BIC is reduced and anisotropic in momentum space. Also, pt -BICs can even appear at off-high symmetry lines of the Brillouin zone. The pt -BICs also carry topological charges and can be created or annihilated with the total charge conserved. A unified picture on pt -BICs and the associated lasing threshold modes is given based on the temporal coupled mode theory. Our findings reveal the new physics arising from the interplay between PT symmetry and BIC in PhC slabs.
Effects of Crushed Zone Damage on Leak-off Velocity in Perforated Carbonates (2017)

Summary In cased hole carbonate wells, perforations are utilized to connect the wellbore to the formation, providing a conduit for stimulation fluid injection and reservoir production. Conventional hypotheses predict that when acid is injected in perforated carbonates, wormholes should nucleate at the tip of the perforation tunnel ( Huang et al. 2000 ). This assertion is based on models for the leak-off distribution along uniform-diameter perforation tunnels in which the effects of crushed zone damage are ignored. In contradiction to this hypothesis, recent studies have shown many examples in which dominant wormholes nucleate well behind the tunnel tip in perforated core experiments ( Rabie et al. 2013 ). This is interesting considering the fact that the effects of flow localization at the tunnel tip are believed to be exaggerated in axial core flow experiments owing to the influence of the no-flow boundary.
Novel proposal and assessment of a solar-powered supercritical CO2 cycle integrated with adsorption desalination system for electricity, heating and desalination (2023)

This paper presents a thermodynamic performance evaluation of a novel solar based supercritical CO2 (S-CO2) cycle and low temperature adsorption desalination (AD) cycle for power, heating, and freshwater. This novel technology utilizes molten salt as a medium for thermal energy transfer in the solar tower collector and generates power and heating by utilizing the S-CO2 cycle, as well as the AD cycle with heat recovery using aluminium fumarate material to produce freshwater. A parametric investigation is established in order to numerically assess the influence of different parameters on the performance parameters of the novel proposed system. Results show that the thermal efficiency of the solar tower receiver improves from 89.12% to 90.53%, when DNI rises from 900 W/m2 to 1100 W/m2. The thermal and exergy efficiencies of the S-CO2 power cycle are found to be higher at 1100 W/m2 and it is ranged from 33.4% to 44.81% and 54.2%–72.52% respectively, with the rise in inlet pressure of the expander from 12000 kPa to 18000 kPa. In addition, the thermal efficiency of electrical and heating was obtained 25.33% and 10.13%, respectively, at operating conditions. The highest SDWP was achieved 12.5 m3/ton/day and 0.62 GOR at a fixed operating condition.
Rate and Outage Probability in Dual Band Systems With Prediction-Based Band Switching (2018)

5G cellular systems will have the ability to communicate in either centimeter-wave or millimeter-wave bands, though not necessarily in both bands simultaneously. Therefore, techniques to optimize switching between those bands are needed. In this letter, we propose a suitable scheme based on rate prediction. Specifically, in each time-frame the base-station predicts the state of large-scale fading for the next time-frame; data transmission is then carried over the band that is anticipated to achieve the larger data rate. We analyze the scheme based on the assumption that large-scale fading is lognormally distributed and with a finite correlation between the two bands.
Integrated Pockels laser (2022)

The development of integrated semiconductor lasers has miniaturized traditional bulky laser systems, enabling a wide range of photonic applications. A progression from pure III-V based lasers to III-V/external cavity structures has harnessed low-loss waveguides in different material systems, leading to significant improvements in laser coherence and stability. Despite these successes, however, key functions remain absent. In this work, we address a critical missing function by integrating the Pockels effect into a semiconductor laser. Using a hybrid integrated III-V/Lithium Niobate structure, we demonstrate several essential capabilities that have not existed in previous integrated lasers. These include a record-high frequency modulation speed of 2 exahertz/s (2.0 × 10<sup>18</sup> Hz/s) and fast switching at 50 MHz, both of which are made possible by integration of the electro-optic effect. Moreover, the device co-lases at infrared and visible frequencies via the second-harmonic frequency conversion process, the first such integrated multi-color laser. Combined with its narrow linewidth and wide tunability, this new type of integrated laser holds promise for many applications including LiDAR, microwave photonics, atomic physics, and AR/VR.
A 3.5 to 7 GHz Wideband Differential LNA with gm Enhancement for 5G Applications (2020)

This paper presents a differential wideband low noise amplifier (LNA) targeting 5G applications in 130 nm TSMC CMOS technology. The proposed LNA is based on the capacitive cross-coupled common-gate (CCC-CG) push-pull architecture. The LNA utilizes inductors for wideband input matching that resonate with the input parasitic capacitors. The CCC-CG structure along with a current-reuse PMOS and NMOS technique enhances transconductance, reducing noise figure (NF) and increasing voltage gain. Post-layout simulation results show that the differential LNA achieves a gain of 21 ±1.5 dB, NF of less than 4 dB and IIP3 of higher than -2.5 dBm over the bandwidth of 3.5 to 7 GHz. The LNA consumes 2.4 mA from 1 V supply, and occupies an active area of 0.24 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
Electrical Characteristics of Additively Manufactured Hollow Conductor Coils with Integrated Heat Pipes for Electric Aircraft Applications (2022)

This paper presents an extensive study on the characterization of AlSi <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">10</inf> Mg additively manufactured coils for a 250 kW, 5,000 rpm aircraft surface permanent magnet machine. This study includes DC tests up to 70 A and AC tests up to 100 Arms for frequencies up to 1200 Hz. The experimental results were compared to one of the vendors' test results which shows promising match with less than 4.6% error in electrical resistivity. Moreover, electrical resistivity temperature coefficient of the coils was extracted which enables more accurate analysis at nominal temperatures of the machine. The FEA simulation results further demonstrate the accuracy of the test results with errors within 0.5% in losses. This paper also investigates the effects of heat pipes and their placements in the coil under six different scenarios. Different thermal interfaces were used to examine the thermal management system that shows the effectiveness of the heat pipes used in hollow conductors. Furthermore, FEA results show the effects of heat pipes and a magnetic core on the AM coil losses. Among the most important conclusions of this study are that the heat pipes seem not to cause significant electrical short circuits in the coils and using thermal paste on heat pipes has significant effect on extracting heat from the coils.
Pediatric nasal epithelial cells are less permissive to SARS-CoV-2 replication compared to adult cells (2021)

Abstract Children typically experience more mild symptoms of COVID-19 when compared to adults. There is a strong body of evidence that children are also less susceptible to SARS-CoV-2 infection with the ancestral viral isolate. However, the emergence of SARS-CoV-2 variants of concern (VOCs) has been associated with an increased number of pediatric infections. Whether this is the result of widespread adult vaccination or fundamental changes in the biology of SARS-CoV-2 remains to be determined. Here, we use primary nasal epithelial cells from children and adults, differentiated at an air-liquid interface to show that the ancestral SARS-CoV-2 replicates to significantly lower titers in the nasal epithelial cells of children compared to those of adults. This was associated with a heightened antiviral response to SARS-CoV-2 in the nasal epithelial cells of children. Importantly, the Delta variant also replicated to significantly lower titres in the nasal epithelial cells of children. This trend was markedly less pronounced in the case of Omicron. It is also striking to note that, at least in terms of viral RNA, Omicron replicated better in pediatric NECs compared to both Delta and the ancestral virus. Taken together, these data show that the nasal epithelium of children supports lower infection and replication of ancestral SARS-CoV-2, although this may be changing as the virus evolves.
Dendritic macromolecules at the interface of nanoscience and nanotechnology (2003)

Abstract As a result of their unique architecture and structural as well as functional versatility, dendrimers have generated considerable interest in numerous areas of the physical sciences, engineering, as well as the biological sciences. Both their size ‐ in the 1‐10 nm range ‐ and their globular shape resemble those of many proteins suggesting a host of biomimetic and nanotechnological applications. This brief highlight describes some of our recent work with nascent applications of dendrimers as unimolecular nanoreactors, as nanoscale antennae for energy harvesting and transduction, and as nanosized carriers for diagnostic or therapeutic applications. While implementation of some of these applications may still be distant, the impatient critic might remember that new markets are not created overnight as demonstrated by the slow commercial acceptance of many promising molecules and technologies with development frequently extending decades after their initial discovery.
Interaction of the c-fes proto-oncogene product with the interleukin-4 receptor (1994)

Interleukin-4 (IL-4) regulates proliferation and differentiation of a variety of hematopoietic cell lineages through binding to the IL-4 receptor (IL-4R). Recently, we have demonstrated that IL-4 induces tyrosine phosphorylation of several proteins including the IL-4R and also induces association of phosphatidylinositol-3 kinase with the IL-4R. Since IL-4 induces tyrosine phosphorylation, we speculated that some tyrosine kinase may associate with the IL-4R. In this study, we demonstrate that IL-4 induces tyrosine phosphorylation of a protein closely related to, or identical to the c-fes protooncogene-encoded protein tyrosine kinase (FES). Furthermore, tyrosine phosphorylated FES or the closely related protein is found associated with the IL-4R. We also demonstrate that FES associates with the IL-4R in COS7 cells transfected with cDNA expression plasmids encoding these two proteins and in transfected COS7 cells IL-4 augments association of FES with the IL-4R and tyrosine phosphorylation of both FES and the IL-4R. Through a deletion analysis of the IL-4R we have identified a putative FES-binding site in the cytoplasmic domain of the IL-4R.
ChemInform Abstract: Reaction of 2,5‐Bis(trifluoromethyl)‐1,3,4‐oxadiazole with Primary Amines. Synthesis of 4‐Substituted‐3,5‐bis(trifluoromethyl)‐4H‐1,2,4‐triazoles. (1989)

Abstract Reaction of the bis(trifluoromethyl)oxadiazole (I) with amines such as (II) leads to the title compounds (III) (ca.