gebhart/patrepeval huggingface dataset:
Recent development in pixel level packaging for uncooled IRFPA (2010)

Reducing production costs would contribute to keep on extending applications of uncooled IRFPA to high volume of low cost camera market where weight, power and cost reduction are of importance. Since the first proof of the pixel level packaging for uncooled IRFPA in 2008, CEA-LETI, MINATEC is still strongly involved in an innovative packaging technology. The main point is that no additional technological steps are necessary to integrate the FPA chip under vacuum as the microbolometer process comprises itself the vacuum integration at the pixel level. Moreover, to keep the vacuum level around each microbolometer a thin film getter is deposited. This paper presents the recent development at CEA-LETI, MINATEC of this innovative packaging technology with getter inside.
Multi-resolution VQ: parameter meaning and choice (2002)

In multi-resolution source coding, a single code is used to give an embedded data description that may be decoded at a variety of rates. Recent work in practical multi-resolution coding treats the optimal design of fixed- and variable-rate tree-structured vector quantizers for multi-resolution coding. In that work the codes are optimized for a designer-specified priority schedule over the system rates, distortions, or slopes. The method relies on a collection of parameters, which may be difficult to choose. This paper explores the meaning and choice of the multi-resolution source coding parameters.
“Bottom-Up” Strategy for the Identification of Novel Soybean Peptides with Angiotensin-Converting Enzyme Inhibitory Activity (2020)

IAVPTGVA (Soy1) and LPYP are two soybean peptides, which display a multifunctional behavior, showing in vitro hypocholesterolemic and hypoglycemic activities. A preliminary screening of their structures using BIOPEP suggested that they might be potential angiotensin-converting enzyme (ACE) inhibitors. Therefore, a bottom-up-aided approach was developed in order to clarify the in vitro hypotensive activity. Soy1 and LPYP dropped the intestinal and renal ACE enzyme activity with IC<sub>50</sub> values equal to 14.7 ± 0.28 and 5.0 ± 0.28 μM (Caco-2 cells), and 6.0 ± 0.35 and 6.8 ± 0.20 μM (HK-2 cells), respectively. In parallel, a molecular modeling study suggested their capability to act as competitive inhibitors of this enzyme. Finally, in order to increase both their stability and hypotensive properties, a suitable strategy for the harmless control of their release from a nanomaterial was developed through their encapsulation into the RADA16-assembling peptide.
Simultaneous trapping of magnetic and diamagnetic particle plugs for separations and bioassays (2013)

We demonstrate the application of magnetic forces for the simultaneous trapping of two types of particles, magnetic and diamagnetic, via a single set of magnets. Furthermore, we show how this simple setup can be employed for performing assays with a negative control, or for achieving multiple simultaneous analyses.
Evaluation of changes in serum chemistry in association with feed withdrawal or high dose oral gavage with dextran sodium sulfate- (DSS-) induced gut leakage in broiler chickens (2016)

Dextran sodium sulfate ( DSS: ) has been shown to be effective at inducing enteric inflammation in broiler chickens, resulting in increased leakage of orally administered fluorescein isothiocyanate dextran to circulation. In a previous study, 2 doses of DSS (0.45 g/dose) administered as oral gavage resulted in increased mucosal permeability. The main objective of the present study was to compare serum turbidity in control and DSS treated birds plus with feed restriction ( FR: ), and evaluate the associated serum chemistry. Three independent experiments were conducted with different combinations of treatment groups. In Experiment 1, control full-fed ( CON: ) and DSS full-fed ( FFD: ) with n = 15 birds/group were evaluated, Experiment 2 had groups (n = 15/group) CON, FFD, feed restriction ( FRS: for 34 h), and DSS with feed restriction ( FRD: ), and Experiment 3 (n = 15/group) had CON, FFD, and FRS (29 h FRS). All DSS treated birds received one or 2 doses of DSS by oral gavage (0.45 g/dose/bird). Results showed that, compared to CON group, there was an increase (P < 0.05) in serum turbidity in FFD birds, even though the difference between FRS and FRD was not apparent (P > 0.05). Administration of DSS did not result in increase of serum enzymes such as alanine aminotransferase, aspartate aminotransferase, and lactate dehydrogenase ( LDH: ), nonetheless, the FFD showed lower (P < 0.05) LDH level compared to CON in Experiment 2. Among the various serum chemistry parameters evaluated triglycerides had the highest positive correlation (r<sup>2</sup> = 0.85; P < 0.05) with serum turbidity. DSS administration resulted in decreased serum protein levels, especially albumin. These results suggest that oral gavage with DSS in broiler chicks could result in changes to serum chemistry parameters which could be developed as potential marker/s for gut leakage.
In vitro synthesized TSH receptor as a tool for autoantibody detection (2009)

Immunoprecipitation is a reliable method for the detection of many antigens but so far this has not been applied to the TSH receptor. We demonstrate here a novel assay for the detection of antibodies to the TSH receptor using in vitro synthesized protein. The TSH receptor was translated in vitro as a stable protein of 87 kD (full length) and 50 kD (extracellular), respectively. The 50 kD protein reacted by immunoprecipitation analysis with murine and human monoclonal antibodies, polyclonal rabbit sera and with a proportion of unfractionated Graves' disease sera. A limited form of epitope mapping was achieved with the murine monoclonal antibodies. This assay may serve as a new method for the detection of autoantibodies to the TSH receptor from patients' sera.
COUPLED TORSIONAL CANTILEVERS FOR LABEL-FREE SINGLE MOLECULAR LEVEL BIO-DETECTION AND NANOMATERIALS CHARACTERIZATION (2006)

We have developed a micromachined atomic force microscope cantilever with an integrated force sensor that enables time-resolved measurement of forces between the vibrating tip and the sample in tapping-mode atomic force microscopy. These tip-sample interaction forces depend on the elastic, viscoelastic, and adhesive properties of the sample and are determined by the chemical and structural composition of the material. With this technique we are able to detect biomolecular associations on the molecular level and map chemical compositional variations and physical changes within materials at the nanoscale.
Propagation-based Phase-Contrast X-ray Imaging at a Compact Light Source (2017)

We demonstrate the applicability of propagation-based X-ray phase-contrast imaging at a laser-assisted compact light source with known phantoms and the lungs and airways of a mouse. The Munich Compact Light Source provides a quasi-monochromatic beam with partial spatial coherence, and high flux relative to other non-synchrotron sources (up to 10<sup>10</sup> ph/s). In our study we observe significant edge-enhancement and quantitative phase-retrieval is successfully performed on the known phantom. Furthermore the images of a small animal show the potential for live bio-imaging research studies that capture biological function using short exposures.
Formation of Excimers in Isoquinolinyl Pyrazolate Pt(II) Complexes: Role of Cooperativity Effects (2020)

The interplay between noncovalent interactions involving metal complexes may lead to the formation of aggregates (i.e., ground state dimers, trimers, n-mers, etc.), and this is often linked to dramatic changes in their physical and chemical properties as compared to the original properties of the isolated units. Dimers and trimers can also be formed in the excited state potential energy surfaces, i.e., excimers. Excimers are short-lived but are also often characterized by different optical properties from those of the isolated units. Understanding the nature of noncovalent interactions and the presence or not of cooperativity effects in both aggregates and excimers is thus extremely important to rationalize these variations. In this study, we present computational investigations on isoquinolinyl pyrazolate Pt(II) complexes. Our results highlight that cooperativity effects between noncovalent interactions, which are modulated by sterically demanding substituents and metallophilic Pt···Pt interactions, are present only on certain investigated excimers. We use density functional theory (DFT) calculations to examine the cooperativity effects and the changes in the photophysical properties. Different descriptors of cooperativity effects between noncovalent interactions, including the synergetic, genuine nonadditive, and total interaction energies, were evaluated for a series of Pt(II) aggregates and excimers. In addition, energy decomposition analysis (EDA) calculations were performed to rationalize the origins of the cooperative effects. The cooperative effects in trimer excimers (in their lowest triplet excited state, i.e., T1) led to shortened Pt···Pt contacts as compared to the trimer aggregates. Furthermore, this synergy between noncovalent interactions is ultimately responsible for the formation of the excimers and the striking changes in the measured photophysical properties. More in detail, we report a change in the character of the lowest-lying triplet excited state when going from dimer excimers (i.e., of mixed triplet ligand-centered and triplet metal-to-ligand charge transfer (3LC/3MLCT) character) to trimer excimers (i.e., of triplet metal–metal-to-ligand charge transfer (3MMLCT) character). The EDA reveals that the total interaction energy on trimer excimers is subtly controlled by the electrostatic and dispersion terms.
Analysis of Ageing Effect on Li‐Polymer Batteries (2015)

Lithium-ion batteries are a key technology for current and future energy storage in mobile and stationary application. In particular, they play an important role in the electrification of mobility and therefore the battery lifetime prediction is a fundamental aspect for successful market introduction. Numerous studies developed ageing models capable of predicting battery life span. Most of the previous works compared the effect of the ageing factors to a battery's cycle life. These cycles are identical, which is not the case for electric vehicles applications. Indeed, most of the available information is based on results from laboratory testing, under very controlled environments, and using ageing protocols, which may not correctly reflect the actual utilization. For this reason, it is important to link the effect of duty cycles with the ageing of the batteries. This paper proposes a simple method to investigate the effect of the duty cycle on the batteries lifetime through tests performed on different cells for different kinds of cycle. In this way, a generic complex cycle can be seen as a composition of elemental cycles by means of Rainflow procedures. Consequently, the ageing due to any cycle can be estimated starting from the knowledge of simpler cycles.
Development of a lorentz-force actuated intravitreal jet injector (2012)

Intravitreal injection is a common treatment in ophthalmology, but it can lead to numerous complications. Needle-free jet injection has been shown to successfully deliver fluid to various layers of skin, and, by its nature, may reduce intravitreal injection complications. From injection trials into ex vivo rabbit eyes, we find that needle-free jet injection can be used for intravitreal drug delivery. A custom-designed control scheme, characterized in this study, is crucial to this delivery. The system is capable of delivering 40 µL of fluid to the posterior vitreous humor, with an injection duration less than 100 ms and scleral entry site less than 350 µm in diameter.
Efficiency/effectiveness trade-offs in query processing (from theory into practice workshop, 1998 SIGIR conf.) (1998)

article Free Access Share on Efficiency/effectiveness trade-offs in query processing (from theory into practice workshop, 1998 SIGIR conf.) Author: David Hawking CSIRO Mathematical and Information Sciences, Canberra, Australia CSIRO Mathematical and Information Sciences, Canberra, AustraliaView Profile Authors Info & Claims ACM SIGIR ForumVolume 32Issue 2Sept. 1998 pp 16–22https://doi.org/10.1145/305110.305119Published:01 September 1998Publication History 11citation214DownloadsMetricsTotal Citations11Total Downloads214Last 12 Months7Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
In Planta Visual Monitoring of Green Fluorescent Protein in Transgenic Rice Plants (2000)

The green fluorescent protein (GFP) from the jellyfish Aequorea victoria is a widely used reporter that can be directly visualized in the living cells in both animals and plants. We inserted a synthetic gene (sgfp) encoding a modified form of the GFP into expression vector, Act1-sgfp for the direct expression of GFP which is easily detectable in rice plants. Green fluorescence emitted from GFP could be visualized in calli, dry seeds, roots and seedlings with green shoots of transgenic rice plants. In our visualization system with a charge-coupled device camera, band-pass filters and a light source, the presence of red chlorophyll autofluorescence from chloroplasts did not alter the green fluorescence of GFP. These results demonstrate that GFP could be used as a non-destructive visual selection marker for examining gene expression in transformed calli, dry seeds and young plants.
Relative biological effectiveness of carbon ions for tumor control, acute skin damage and late radiation-induced fibrosis in a mouse model (2015)

The observed RBE values were very similar for tumor response, acute skin damage and late RIF when irradiated with large doses of high- linear energy transfer (LET) carbon ions. This study adds information to the variation in biological effectiveness in different tumor and normal tissue models.
Generation of human monoclonal antibodies that confer protection against pertussis toxin (1992)

A panel of human monoclonal antibodies reactive with pertussis toxin has been generated by means of Epstein-Barr virus infection. One of these, the 3F11 monoclonal antibody, showed the ability to neutralize in vitro and in vivo the toxic effects of the toxin. Western blot (immunoblot) analysis located the 3F11 epitope on the S3 subunit.
Using upper bounds on attainable discrimination to select discrete valued features (2002)

Selection of features that will permit accurate pattern classification is, in general, a difficult task. However, if a particular data set is represented by discrete valued features, it becomes possible to determine empirically the contribution that each feature makes to the discrimination between classes. We describe how to calculate the maximum discrimination possible in a two alternative forced choice decision problem, when discrete valued features are used to represent a given data set. (In this paper, we measure discrimination in terms of the area under the receiver operating characteristic (ROC) curve.) Since this bound corresponds to the upper limit of classification achievable by any classifier (with that given data representation), we can use it to assess whether recognition errors are due to a lack of separability in the data or shortcomings in the classification technique. In comparison to the training and testing of artificial neural networks, the empirical bound on discrimination can be efficiently calculated, allowing an experimenter to decide whether subsequent development of neural network models is warranted. We extend the discrimination bound method so that we can estimate both the maximum and average discrimination we can expect on unseen test data. These estimation techniques are the basis of a backwards elimination algorithm that can be used to rank features in order of their discriminative power. We use two problems to demonstrate this feature selection process: classification of the Mushroom Database, and a real-world, pregnancy related medical risk prediction task-assessment of risk of perinatal death.
Thermal Conductivity of Polymer Copoly(Ethylene Vinyl Acetate)/Nano-Filler Blends (2007)

The development of flexible, thermally conductive fabrics and plastic tubes for the Liquid Cooling and Ventilation Garment (LCVG) are needed to reduce weight and improve the mobility, comfort, and performance of future spacesuits. Such improvements would allow astronauts to operate more efficiently and safely for extended extravehicular activities. As a continuation of our work on the improvement of thermal conductivity (TC) of polymeric materials, nanocomposites were prepared from copoly(ethylene vinyl acetate), trade name Elvax 260TradeMark), metallized carbon nanofibers (CNFs), nickel (Ni) nanostrands, boron nitride both alone and as mixtures with aluminum powder. The nanocomposites were prepared by melt mixing at various loading levels and subsequently fabricated into several material forms (i.e., ribbons, tubes, and compression molded plaques) for analysis. Ribbons and tubes were extruded to form samples in which the nanoparticles were aligned in the direction of flow. The degree of dispersion and alignment of the nanoparticles were investigated using high-resolution scanning electron microscopy. Tensile properties of the aligned samples were determined at room temperature. TC measurements were performed using a laser flash (Nanoflash(TradeMark) technique. The TC of the samples was measured in both the direction of alignment as well as transverse. Tubing of comparable dimensions to that used in the LCVG was extruded from select compositions and the thermal conductivities of the tubes measured.
Prioritizing soft real-time network traffic in virtualized hosts based on Xen (2015)

As virtualization technology becomes ever more capable, large-scale distributed applications are increasingly deployed in virtualized environments such as data centers and computational clouds. Many large-scale applications have soft real-time requirements and benefit from low and predictable latency, even in the presence of diverse traffic patterns between virtualized hosts. In this paper, we examine the policies and mechanisms affecting communication latency between virtual machines based on the Xen platform, and identify limitations that could result in long or unpredictable network traffic latencies. To address these limitations, we propose VATC, a <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Virtualization-Aware Traffic Control</i> framework for prioritizing network traffic in virtualized hosts. Results of our experiments show how and why VATC can improve predictability and reduce delay for latency sensitive applications, while introducing limited overhead.
M4M: A model for enabling social network based sharing in the Internet of Things (2015)

The true potential of the Internet of Things (IoT) will be realized only when devices are able to harness the collective capabilities of a wide range of peer-devices. In this paper, we propose a novel model where friends in a social network can share device capabilities with their peers in an access controlled manner. We develop a theoretical model of such a peer-to-peer network in which devices can search for remote capabilities, and elaborate on the trade-offs of different algorithms in terms of capability searching and execution. We study various types of social network models to understand the degree of sharing in such networks. Our results show that Barabási-Albert graphs that approximate most real world social networks have a high degree of sharing, validating the utility of our social network based model. We also propose an algorithm that takes any given network and augments it to increase the level of sharing by intelligently suggesting friendship recommendations among vertices. Finally, we describe the prototype implementation of an android mobile application that uses facebook APIs to allow smartphones share GPS and camera capabilities with other devices owned by friends.
Image restoration and disparity estimation from an uncalibrated multi-layered image (2010)

Watching a reflection in a glass window, one can often observe a multi-layered image consisting of a front-surface reflection from the glass and a rear-surface reflection through the glass. That multi-layered image is a composition of dual aspects of the same image, resembling a sound reverberation. As described herein, we propose a method to estimate the original reflection image before the layering. First, we model the multi-layered image generation process; then we derive a restoration filter by assuming that the displacement between the multiple reflection images in the single multi-layered image is known. Second, we propose a method to estimate the original image in conjunction with the displacement estimation. The displacement between the reflection images in a single multi-layered image includes scene depth information. Finally, we demonstrate the effectiveness of our proposed method using both synthetic and real multi-layered images.
Meta-analysis of organ-specific differences in the structure of the immune infiltrate in major malignancies (2015)

Anticancer immunosurveillance is one of the major endogenous breaks of tumor progression. Here, we analyzed gene expression pattern indicative of the presence of distinct leukocyte subtypes within four cancer types (breast cancer, colorectal carcinoma, melanoma, and non-small cell lung cancer) and 20 different microarray datasets corresponding to a total of 3471 patients. Multiple metagenes reflecting the presence of such immune cell subtypes were highly reproducible across distinct cohorts. Nonetheless, there were sizable differences in the correlation patterns among such immune-relevant metagenes across distinct malignancies. The reproducibility of the correlations among immune-relevant metagenes was highest in breast cancer (followed by colorectal cancer, non-small cell lung cancer and melanoma), reflecting the fact that mammary carcinoma has an intrinsically better prognosis than the three other malignancies. Among breast cancer patients, we found that the expression of a lysosomal enzyme-related metagene centered around ASAH1 (which codes for N-acylsphingosine amidohydrolase-1, also called acid ceramidase) exhibited a higher correlation with multiple immune-relevant metagenes in patients that responded to neoadjuvant chemotherapy than in non-responders. Altogether, this meta-analysis revealed novel organ-specific features of the immune infiltrate in distinct cancer types, as well as a strategy for defining new prognostic biomarkers.
Design and determination of radial air swirler blade lengths using CFD (2001)

The effect of blade length on the swirl strength inside a combustor with a radial air swirler is analyzed using computational fluid dynamics (CFD). The objective is to determine the blade length that produces a flow field with the strongest swirl and recirculation for a given swirler blade angle. The air swirler analyzed in this study has fifteen blades, each inclined at 60° from the radius. The swirler is attached atop a cylindrical combustor. Swirl numbers for various blade lengths are calculated, and the size of the recirculation zones are compared. Both the size of the recirculation zone and swirl number have maximum values at L/W=l.8, where L is blade length and W blade spacing.