gebhart/patrepeval huggingface dataset:
Responses of the Bovine Mammary Artery to Angiotensins (1993)

The main objective of our study was to determine whether angiotensins cause vasoconstriction of mammary arterial segments in vitro. Once this action was established, its specificity was determined. Mammary arterial sections were obtained from lactating cattle at slaughter. Vessel sections were placed in a gravity-fed, closed, perfusion apparatus, and flow was measured by a transit-time flow sensor mounted in-line. Treatments were administered by injection into a leurlock port located proximal to the sensor. Angiotensins I, II, and III induced a dose-dependent vasoconstriction of arterial segments at concentrations of 5 x 10(-10) to 5 x 10(-6) M. Angiotensin II receptor antagonists, Saralisin and (Sarl, Thr8)-angiotensin II (5 x 10(-8) M)), inhibited vasoconstriction induced by angiotensins I, II, and III. The angiotensin-converting enzyme inhibitor, Captopril (5 x 10(-8) M), inhibited angiotensin I vasoconstriction, thereby showing that the vasoconstriction by angiotensin I was mediated through its conversion to angiotensin II. These data demonstrated that the mammary artery of lactating cows is responsive to the angiotensin family. Furthermore, mammary arteries contain angiotensin-converting enzyme and specific receptors for angiotensin II. This system may be important in the normal physiological regulation of mammary gland blood flow of lactating cows.
Five-dimensional interpolation: Recovering from acquisition constraints (2009)

Abstract Although 3D seismic data are being acquired in larger volumes than ever before, the spatial sampling of these volumes is not always adequate for certain seismic processes. This is especially true of marine and land wide-azimuth acquisitions, leading to the development of multidimensional data interpolation techniques. Simultaneous interpolation in all five seismic data dimensions (inline, crossline, offset, azimuth, and frequency) has great utility in predicting missing data with correct amplitude and phase variations. Although there are many techniques that can be implemented in five dimensions, this study focused on sparse Fourier reconstruction. The success of Fourier interpolation methods depends largely on two factors: (1) having efficient Fourier transform operators that permit the use of large multidimensional data windows and (2) constraining the spatial spectrum along dimensions where seismic amplitudes change slowly so that the sparseness and band limitation assumptions remain valid. Fourier reconstruction can be performed when enforcing a sparseness constraint on the 4D spatial spectrum obtained from frequency slices of five-dimensional windows. Binning spatial positions into a fine 4D grid facilitates the use of the FFT, which helps on the convergence of the inversion algorithm. This improves the results and computational efficiency. The 5D interpolation can successfully interpolate sparse data, improve AVO analysis, and reduce migration artifacts. Target geometries for optimal interpolation and regularization of land data can be classified in terms of whether they preserve the original data and whether they are designed to achieve surface or subsurface consistency.
Chirality Induced Lateral Optical Force (2013)

Light can exert radiation pressure on any object it encounters and that resulting optical force can be used to manipulate particles. It is commonly assumed that light should move a particle forward and indeed an incident plane wave with a photon momentum hk can only push any particle, independent of its properties, in the direction of k. Here we demonstrate using full-wave simulations that an anomalous lateral force can be induced in a direction perpendicular to that of the incident photon momentum if a chiral particle is placed above a substrate that does not break any left-right symmetry. Analytical theory shows that the lateral force emerges from the coupling between structural chirality (the handedness of the chiral particle) and the light reflected from the substrate surface. Such coupling induces a sideway force that pushes chiral particles with opposite handedness in opposite directions.
Probing the photothermally induced phase transitions in single-crystalline vanadium dioxide nanobeams (2013)

Using Raman spectroscopy, we demonstrated photothermally induced crystallographic phase transitions of vanadium dioxide (VO2) nanobeams clamped to and free-standing on a substrate. Compared to the temperature-dependent Raman measurements, the laser-power-dependent Raman characteristics provide substantial evidence for the photothermal origin of the phase transitions of the VO2 nanobeams. The laser power necessary to cause phase transitions in the free-standing nanobeam was approximately eight times smaller than the laser power used in the substrate-clamped nanobeam. Our study will enhance the understanding of the complex phase transitions of strongly correlated oxides and thereby provide a foundation for engineering desirable properties in novel devices.
Wireless Power Transmitter Deployment for Balancing Fairness and Charging Service Quality (2020)

Wireless Energy Transfer (WET) has recently emerged as an appealing solution for power supplying mobile / Internet of Things (IoT) devices. As an enabling WET technology, Resonant Beam Charging (RBC) is well-documented for its long-range, high-power, and safe "WiFi-like" mobile power supply. To provide high-quality wireless charging services for multi-user in a given region, we formulate a deployment problem of multiple RBC transmitters for balancing the charging fairness and quality of charging service. Based on the RBC transmitter's coverage model and receiver's charging / discharging model, a Genetic Algorithm (GA)-based and a Particle Swarm Optimization (PSO)-based scheme are put forth to resolve the above issue. Moreover, we present a scheduling method to evaluate the performance of the proposed algorithms. Numerical results corroborate that the optimized deployment schemes outperform uniform and random deployment in 10%-20% charging efficiency improvement.
The Suspension of Large Bubbles Near the Sea Surface by Turbulence and Their Role in Absorbing Forward-Scattered Sound (2013)

There is anecdotal evidence that under conditions of moderate to high wind speeds (8-15 m ·s <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">- 1</sup> ), clouds of bubbles entrained in the near-surface layer by breaking waves can create a benign underwater communications channel through the resonant absorption of forward-scattered sound, reducing reverberation times and the occurrence of high-intensity, Doppler-shifted arrivals. Current models for the effects of bubbles on surface-interacting sound show two effects: refraction of low-frequency sound due to reductions in sound speed near the surface and resonant absorption at higher frequencies. These models include uncertainty in the numbers and sizes of the largest bubbles present in the near-surface layer, and their dependence on wind speed. This uncertainty makes quantitative prediction of bubble effects in the underwater acoustic communications band of workhorse frequencies (10-30 kHz) difficult. The model calculations presented here show that resonant absorption associated with the largest bubbles is strongly frequency and wind-speed dependent. The frequency dependence can be explained by the concept of a bubble escape radius; this being the radius of a bubble for which turbulent fluid velocity fluctuations and bubble terminal velocity in the upper ocean boundary layer balance. Bubbles smaller than the escape radius tend to remain trapped by fluid turbulence while larger bubbles are lost to the surface through buoyant degassing. Calculation of the escape radius provides a means of estimating the lowest frequency at which resonant absorption can be expected for a given wind speed. Initial estimates suggest that resonant absorption at 10 kHz begins at 10-m wind speeds of around 8 ms <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> , and significant surface bounce losses at frequencies lower than this are expected in the range of wind speeds 13-20 m·s <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">- 1</sup> .
Transport Considerations for the Critically III Child (1997)

Transport of the critically ill child to and between hospitals has become a specialty field. Proper preparation and planning is critical on the part of the transferring party, the receiving facility, and the transport crew. Optimal patient outcome occurs when all parties involved understand each other and work together. Indications for transport, determination of transport mode, crew configuration of the transport team, necessary equipment, and physical examination including clinical interventions are key components of a successful transport. The following is a brief overview of these specific considerations involved when transporting the critically ill child.
Semi-crowdsourced Clustering with Deep Generative Models (2018)

We consider the semi-supervised clustering problem where crowdsourcing provides noisy information about the pairwise comparisons on a small subset of data, i.e., whether a sample pair is in the same cluster. We propose a new approach that includes a deep generative model (DGM) to characterize low-level features of the data, and a statistical relational model for noisy pairwise annotations on its subset. The two parts share the latent variables. To make the model automatically trade-off between its complexity and fitting data, we also develop its fully Bayesian variant. The challenge of inference is addressed by fast (natural-gradient) stochastic variational inference algorithms, where we effectively combine variational message passing for the relational part and amortized learning of the DGM under a unified framework. Empirical results on synthetic and real-world datasets show that our model outperforms previous crowdsourced clustering methods.
Building on a National Health Information Technology Strategic Plan for Long-Term and Post-Acute Care: Comments by the Long Term Post Acute Care Health Information Technology Collaborative (2011)

The LTPAC (Long Term Post Acute Care) Health Information Technology (HIT) Collaborative consists of an alliance of long-term services and post-acute care stakeholders. Members of the collaborative are actively promoting HIT innovations in long-term care settings because IT adoption for health care institutions in the United States has become a high priority. One method used to actively promote HIT is providing expert comments on important documents addressing HIT adoption. Recently, the Office of the National Coordinator for HIT released a draft of the Federal Health Information Technology Strategic Plan 2011-2015 for public comment. The following brief is intended to inform about recommendations and comments made by the Collaborative on the strategic plan.
Agent‐based modeling of malware dynamics in heterogeneous environments (2011)

ABSTRACT The increasing convergence of power‐law networks such as social networking and peer‐to‐peer applications, web‐delivered applications, and mobile platforms makes today's users highly vulnerable to entirely new generations of malware that exploit vulnerabilities in web applications and mobile platforms for new infections, while using the power‐law connectivity for finding new victims. The traditional epidemic models based on assumptions of homogeneity, average‐degree distributions, and perfect‐mixing are inadequate to model this type of malware propagation. In this paper, we study four aspects crucial to modeling malware propagation: application‐level interactions among users of such networks , local network structure , user mobility , and network coordination of malware such as botnets . Since closed‐form solutions of malware propagation considering these aspects are difficult to obtain, we describe an open‐source, flexible agent‐based emulation framework that can be used by malware researchers for studying today's complex malware. The framework, called Agent‐Based Malware Modeling (AMM), allows different applications, network structure, network coordination, and user mobility in either a geographic or a logical domain to study various infection and propagation scenarios. In addition to traditional worms and viruses, the framework also allows modeling network coordination of malware such as botnets. The majority of the parameters used in the framework can be derived from real‐life network traces collected from a network, and therefore, represent realistic malware propagation and infection scenarios. As representative examples, we examine two well‐known malware spreading mechanisms: (i) a malicious virus such as Cabir spreading among the subscribers of a cellular network using Bluetooth and (ii) a hybrid worm that exploit email and file‐sharing to infect users of a social network. In both cases, we identify the parameters most important to the spread of the epidemic based upon our extensive simulation results. Copyright © 2011 John Wiley &amp; Sons, Ltd.
Dipole−Dipole Electronic Energy Transfer. Fluorescence Decay Functions for Arbitrary Distributions of Donors and Acceptors. II. Systems with Spherical Symmetry (1997)

Many interesting systems of nanometer dimensions form spherically symmetric domains, either by design or through spontaneous self-assembly. The technique of direct nonradiative resonance energy transfer (DET) can be used to characterize the morphology of such structures on a nanometer scale. One needs to label the domain of interest with appropriate donor and acceptor dye moieties. One measures the fluorescence decay of the donors (ID(t)) in the presence of acceptors. The underlying geometry and physics of the system dictate how the dyes distribute themselves along the radial axis R of the system, according to concentration profiles (CD(R), and CA(R)) which need not be uniform. Because DET is sensitive to the distribution of dye interdistances, ID(t) contains information about the underlying morphology. In this work we obtain an analytic expression relating ID(t) to the donor/acceptor concentration profiles. This extends our previous contribution for systems with a plane of symmetry. The expression developed is general and capable of handling geometries in both extended and/or restricted spaces. It does not require a specific spatial locus for the donors nor does it require prior calculation of the pair-distribution function of the donor−acceptor distances. The development also provides one with an analytic expression for the evaluation of the interdistance distribution functions.
Improved Crimp-Joining of Aluminum Tubes onto Mandrels with Undulating Surfaces (2004)

Over its history electromagnetic forming (EMF) has probably seen far and away more application in assembling tubes or rings onto (or into) nominally axisymmetric mating elements. The vast majority of these assemblies does not require any significant structural integrity or strength. However, a small fraction of these are designed and fabricated for mechanically-demanding applications. There are two key factors (which seem to be largely independent) that are key in the design and performance of a crimpedelectromagnetic tube joint. First is the state of residual stress that exists after the crimped joint is created. A natural interference fit seems to be a fairly general feature of EMF crimp joints. This interference gives a backlash-free joint that will not fret. The second key issue is the configuration of the joint. The fabrication of designed interlocking geometries is required to create a joint that maximizes mechanical strength while minimizing the electromagnetic energy and forces required to create it. Both of these issues will be considered here. Here we consider crimping onto textured surfaces such as screw threads and knurls. We show experimentally that approaches of this type can give joints that exceed the strength of the tube both in torsion and axial loading. Analysis methods based on coupling impact-indentation and break-before-strip criteria can be used to compare joints made in this way with those based on the more traditional large scale deformation of the tube. One of the advantages of forming onto 'textured' surfaces is that a number of small pulses (possibly generated by small and inexpensive capacitor banks) can be used to create a joint that has the strength of the parent tube, without any heat affected zones or distortion. Again, the natural interference fit developed by impact eliminates the potential for fretting.
Time-dependent Effects of Pressure during Preservation of Rat Hearts in an Isochoric System at Subfreezing Temperatures. (2019)

The enhanced hydrostatic pressure encountered during isochoric preservation yields time-dependent negative effects on the heart, which can potentially be alleviated by the addition of a cryoprotectant.
Complete genome of the switchgrass endophyte Enterobacter clocace P101 (2014)

The Enterobacter cloacae complex is genetically very diverse. The increasing number of complete genomic sequences of E. cloacae is helping to determine the exact relationship among members of the complex. E. cloacae P101 is an endophyte of switchgrass (Panicum virgatum) and is closely related to other E. cloacae strains isolated from plants. The P101 genome consists of a 5,369,929 bp chromosome. The chromosome has 5,164 protein-coding regions, 100 tRNA sequences, and 8 rRNA operons.
The domain on the Duffy blood group antigen for binding Plasmodium vivax and P. knowlesi malarial parasites to erythrocytes. (1996)

Plasmodium vivax and the related simian malarial parasite P. knowlesi use the Duffy blood group antigen as a receptor to invade human erythrocytes and region II of the parasite ligands for binding to this erythrocyte receptor. Here, we identify the peptide within the Duffy blood group antigen of human and rhesus erythrocytes to which the P. vivax and P. knowlesi ligands bind. Peptides from the NH2-terminal extracellular region of the Duffy antigen were tested for their ability to block the binding of erythrocytes to transfected Cos cells expressing on their surface region II of the Duffy-binding ligands. The binding site on the human Duffy antigen used by both the P. vivax and P. knowlesi ligands maps to a 35-amino acid region. A 34-amino acid peptide from the equivalent region of the rhesus Duffy antigen blocked the binding of P. vivax to human erythrocytes, although the P. vivax ligand expressed on Cos cells does not bind rhesus erythrocytes. The binding of the rhesus peptide, but not the rhesus erythrocyte, to the P. vivax ligand was explained by interference of carbohydrate with the binding process. Rhesus erythrocytes, treated with N-glycanase, bound specifically to P. vivax region II. Thus, the interaction of P. vivax ligand with human and rhesus erythrocytes appears to be mediated by a peptide-peptide interaction. Glycosylation of the rhesus Duffy antigen appears to block binding of the P. vivax ligand to rhesus erythrocytes.
Optimisation des boucles d’allocation pour DVB-RCS (2007)

International audience
Production of gastrin-releasing peptide by a non-small cell lung carcinoma cell line adapted to serum-free and growth factor-free conditions. (1994)

Gastrin-releasing peptide is an important growth-modulating factor in developing lung epithelium. It is known to be produced by small cell carcinomas of the lung, and an autocrine loop involving gastrin-releasing peptide and its receptor has been demonstrated in many small cell lung tumors. We investigated whether such an autocrine loop could also be demonstrated in non-small cell lung carcinoma, since gastrin-releasing peptide is known to stimulate human bronchial epithelial cells, from which non-small cell tumors should emerge. We report here that gastrin-releasing peptide is produced by a bronchiolo-alveolar carcinoma cell line (A549) adapted to serum-free and growth factor-free conditions. A549 cells adapted to these conditions, termed A549-R0 cells, display extensive membrane interdigitations, Golgi apparatus, and secretory-like granules, and grow as a mixture of attached colonies and floating cells. Gastrin-releasing peptide is present in the conditioned medium produced by A549-R0 cells. Colony formation of cells derived from a squamous cell carcinoma of the lung, 239T, was stimulated 9-fold by A549-R0 conditioned medium or by authentic gastrin-releasing peptide, measured in serum-free conditions. The growth stimulatory activity was inhibited by a monoclonal antibody to gastrin-releasing peptide. Transcripts for receptors for the bombesin family of peptides were also demonstrated in A549-R0 cells and 239T cells. These results demonstrate that non-small cell lung carcinomas can secrete gastrin-releasing peptide and can also respond to the peptide.
Silicon micromachined ultrasonic transducer for cutting applications with improved power transfer (2012)

SAMLAB
Star Block Copolymers and Hexafullerene Stars via Derivatization of Star-Shaped Polystyrenes (1999)

The end-functionalization of hexaarm star-shaped polystyrene (PS), prepared via “living” cationic polymerization, by organosilicon compounds was investigated. The presence of a sec-chlorine atom at each branch end was first confirmed by 1H NMR. After activation of these chain ends by TiCl4, both allylic and azido groups were introduced through the use of their trimethylsilyl derivatives (allyltrimethylsilane and trimethylsilyl azide, respectively), particularly taking advantage of the high affinity of silicon compounds toward electrophilic reagents. These end-standing allyl and azide functions on the hexaarm PS stars were then transformed into hydroxyl and amino groups with use of classical organic chemistry reactions. PS stars carrying six fullerenes on their periphery were also generated from hexaazido star samples. The presence of these six C60 entities was confirmed by miscellaneous characterization methods, including 1H NMR, size-exclusion chromatography, thermal gravimetry, and cyclic voltammetry. Besides the synthesis of these ω-functionalized stars, PS6-b-PEO6 star block copolymers were also prepared with use of the hexahydroxy samples as macroinitiators of ethylene oxide polymerization.
Substance P in the localization of a carcinoid tumor (1984)

A 55-year-old woman with an ovarian carcinoid presented with intermittent facial and cervical flushing for 10 years, watery diarrhea for 4 years, and abdominal pain without hepatomegaly. Markedly elevated systemic venous and arterial serotonin levels (830 ng/ml; nl = 50-200 ng/ml) were found. The highest serotonin levels were observed in the superior vena caval system, but serotonin as a marker for tumor localization was inaccurate and led to an unproductive neck exploration. The histological pattern of this tumor contained purely insular elements. No hepatic or nodal metastases were identified and the lesion was unilateral. Substance P levels were elevated in the venous drainage of the left ovary and in retrospect correctly localized the ovarian tumor. This peptide may prove to be another carcinoid tumor marker in addition to serotonin and 5-hydroxyindoleacetic acid. Substance P may also be an important mediator of symptoms in patients with carcinoid syndrome.