gebhart/patrepeval huggingface dataset:
Use of antisense RNA to confer bacteriophage resistance in dairy starter cultures (1992)

The strategy and implementation of a unique system for engineering bacteriophage resistant starter cultures of Lactococcus lactis employing antisense RNA is reviewed. As a necessary prerequisite for developing this system, we have cloned and sequenced a number of bacteriophage genes coding for minor and major structural proteins. In addition, we have also identified a series of genes whose function(s) is not known but their sequences appear to be conserved in a vast number of isolates. One of these latter sequences, designated gp51C, codes for a 51-kDa protein which is extremely charged and shares some homology with yeast translation initiation factor. Resistance to a broad class of isometric bacteriophages has been achieved by expression of an antisense RNA targeted against, for example, gp51C. In the best case, expression of the antisense gp51C RNA results is a greater than 99% reduction in the total number of plaque forming units. Additional antisense RNA constructs directed against other bacteriophage genes, including the major capsid protein, also appear effective at inhibiting infection from 40-55% suggesting that this approach may prove useful for engineering a set of truly isogenic strains to be used in a starter culture rotation plan.
Naphthalene dianhydride organic anode for a ‘rocking-chair’ zinc–proton hybrid ion battery (2021)

Rechargeable batteries consisting of a Zn metal anode and a suitable cathode coupled with a Zn<sup>2+</sup> ion-conducting electrolyte are recently emerging as promising energy storage devices for stationary applications. However, the formation of high surface area Zn (HSAZ) architectures on the metallic Zn anode deteriorates their performance upon prolonged cycling. In this work, we demonstrate the application of 1,4,5,8-naphthalenetetracarboxylic dianhydride (NTCDA), an organic compound, as a replacement for the Zn-metal anode enabling the design of a 'rocking-chair'zinc-proton hybrid ion battery. The NTCDA electrode material displays a multi-plateau redox behaviour, delivering a specific discharge capacity of 143 mA h g<sup>-1</sup> in the potential window of 1.4 V to 0.3 V vs. Zn|Zn<sup>2+</sup>. The detailed electrochemical characterization of NTCDA in various electrolytes (an aqueous solution of 1 M ZnOTF, an aqueous solution of 0.01 M H<sub>2</sub>SO<sub>4</sub>, and an organic electrolyte of 0.5 M ZnOTF/acetonitrile) reveals that the redox processes leading to charge storage involve a contribution from both H<sup>+</sup> and Zn<sup>2+</sup>. The performance of NTCDA as an anode is further demonstrated by pairing it with a MnO<sub>2</sub> cathode, and the resulting MnO<sub>2</sub>||NTCDA full-cell (zinc-proton hybrid ion battery) delivers a specific discharge capacity of 41 mA h g<sub>total</sub><sup>-1</sup> (normalized with the total mass-loading of both anode and cathode active materials) with an average operating voltage of 0.80 V.
Automatic delineation of myocardial contours in late-enhancement long-axis cardiac MR images (2009)

The authors would like to thank the editor, BioMed Central, for the open access to the publication
Ultrahard magnetism from mixed-valence dilanthanide complexes with metal-metal bonding (2022)

Magnetic effects of lanthanide bonding Lanthanide coordination compounds have attracted attention for their persistent magnetic properties near liquid nitrogen temperature, well above alternative molecular magnets. Gould <i>et al</i>. report that introducing metal-metal bonding can enhance coercivity. Reduction of iodide-bridged terbium or dysprosium dimers resulted in a single electron bond between the metals, which enforced alignment of the other valence electrons. The resultant coercive fields exceeded 14 tesla below 50 and 60 kelvin for the terbium and dysprosium compounds, respectively. —JSY
Chlorophyll a sensitized redox processes in microemulsion systems (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChlorophyll a sensitized redox processes in microemulsion systemsJ. Kiwi and M. GraetzelCite this: J. Phys. Chem. 1980, 84, 12, 1503–1507Publication Date (Print):June 1, 1980Publication History Published online1 May 2002Published inissue 1 June 1980https://pubs.acs.org/doi/10.1021/j100449a016https://doi.org/10.1021/j100449a016research-articleACS PublicationsRequest reuse permissionsArticle Views82Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
University of Twente at the TREC 2007 Enterprise Track : modeling relevance propagation for the expert search task (2007)

This paper describes several approaches which we used for the expert search task of the TREC 2007 Enterprise track. We studied several methods of relevance propagation from documents to related candidate experts. Instead of one- step propagation from documents to directly related candi- dates, used by many systems in the previous years, we do not limit the relevance ow and disseminate it further through mutual documents-candidates connections. We model rele- vance propagation using random walk principles, or in for- mal terms, discrete Markov processes. We experiment with innite and nite number of propagation steps. We also demonstrate how additional information, namely hyperlinks among documents, organizational structure of the enterprise and relevance feedback may be utilized by the presented techniques.
A wireless, low-drift, implantable intraocular pressure sensor with parylene-on-oil encapsulation (2018)

This paper presents a wireless, implantable continuous intraocular pressure (IOP) monitoring system that features a parylene-on-oil sensor encapsulation method for achieving long-term low-drift in vivo. The system is implanted in the superotemporal quadrant of the eye between the sclera and conjunctiva. It consists of a commercial pressure sensor (STMicroelectronics LPS25H) with digital readout, a 65nm CMOS chip that supports wireless power/data telemetry and the I2C serial communication interface with the pressure sensor. The chip and pressure sensor are assembled on a flexible polyimide PCB, and then the sensor is submerged in biocompatible silicone oil and coated with parylene in situ. The implant uses an on-chip integrated RF coil to receive power from near-field RF coupling at 915 MHz and transmit measurement bits via RF-backscattering to an external reader. A 2 mm × 1.2 mm chip is fabricated in TSMC 65nm CMOS process. The IOP implant achieves a pressure sensitivity of 0.17 mmHg with a total power consumption of 9.7μW. We demonstrate pressure offset drift of less than 0.5 mmHg for more than 4 months over a temperature range of 27-38 °C. The implant successfully tracks induced IOP variations in a porcine eye ex vivo, validating the system functionality and surgical implantation.
SIMPLIFIED COMPUTATION OF LOG-LIKELIHOOD RATIO VALUES FOR HIGH-ORDER MODULATIONS (2015)

This paper proposes a method to approximately compute log-likelihood ratio (LLR) values with reduced complexity. Conventionally, the maximum-likelihood (ML) method is used as the optimum LLR computation method in terms of reception performance. However, the ML method has a drawback that its computational complexity increases exponentially with the modulation order of the system. Although this complexity issue may not significantly affect the reception time with low modulation orders, when high order modulations such as 4096-quadrature amplitude modulation (QAM) are used the ML method may not be used due to its enormous amount of computations. In this respect, this paper proposes an approximation to compute the LLR values. The proposed method requires only M one-dimensional (1D) Euclidian distances for one modulated symbol while the ML method needs 2M 2D distances which may not be implementable with high order modulation. As a cost of the complexity reduction, the proposed method shows an acceptable performance degradation.
Single-image reflection removal using conditional GANs (2019)

Removing undesired reflections from a single-image is inherently ill-posed problem since defining its exact physical model is almost impossible. Most previous works tackle this problem through the use of multiple images or hand-crafted features. These methods are still quite limited in terms of the generality and photo-realistic result. In this paper, we propose a conditional Generative Adversarial Networks based deep neural network structure to render realistic image and formulate our problem in a simple objective function. Specifically, we use gradient information to elaborate this formulation to preserve both low and high frequency details. Our proposed network does not rely on any physical prior information and performs effectively with a single-image. Experimental results demonstrate that proposed algorithm conducts favorably against existing algorithms from human perceptual aspect.
ChemInform Abstract: β‐Lactamase Inhibitors: Synthesis and in vitro Evaluation of 6‐(( 1‐Substituted‐1,2,3‐triazol‐4‐yl)methylene)‐penicillanic Acid Sulfones. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
NUCLEAR MAGNETIC RESONANCE IMAGING OF VASCULATURE OF ABDOMINAL VISCERA. NORMAL AND PATHOLOGIC FINDINGS (1983)

Higgins, C B M.D.; Goldberg, H I M.D.; Hricàk, H M.D.; Herfkens, R. M.D.; Lipton, M J M.D.; Crooks, L C Ph.D.; Kaufman, L. Ph.D. Author Information
Faculty Opinions recommendation of The exerkine apelin reverses age-associated sarcopenia. (2018)

Sarcopenia, the degenerative loss of skeletal muscle mass, quality and strength, lacks early diagnostic tools and new therapeutic strategies to prevent the frailty-to-disability transition often responsible for the medical institutionalization of elderly individuals. Herein we report that production of the endogenous peptide apelin, induced by muscle contraction, is reduced in an age-dependent manner in humans and rodents and is positively associated with the beneficial effects of exercise in older persons. Mice deficient in either apelin or its receptor (APLNR) presented dramatic alterations in muscle function with increasing age. Various strategies that restored apelin signaling during aging further demonstrated that this peptide considerably enhanced muscle function by triggering mitochondriogenesis, autophagy and anti-inflammatory pathways in myofibers as well as enhancing the regenerative capacity by targeting muscle stem cells. Taken together, these findings revealed positive regulatory feedback between physical activity, apelin and muscle function and identified apelin both as a tool for diagnosis of early sarcopenia and as the target of an innovative pharmacological strategy to prevent age-associated muscle weakness and restore physical autonomy. PMID: 30061698
1‐Butyl‐3‐methylimidazolium 3,5‐Dinitro‐1,2,4‐triazolate: A Novel Ionic Liquid Containing a Rigid, Planar Energetic Anion (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Design and Synthesis of Cyclic ADP‐4‐Thioribose as a Stable Equivalent of Cyclic ADP‐Ribose, a Calcium Ion‐Mobilizing Second Messenger (2013)

Oh, what a difference an S makes: A thioribose analogue (cADPtR, see scheme) of cyclic ADP-ribose (cADPR) was synthesized that is stable and has structural and electrostatic features similar to those of cADPR. cADPtR is the first stable equivalent of cADPR that is as active as cADPR in various cellular systems, making it useful for investigating Ca2+ ion-release signaling pathways.
A Novel Method for Assessing Prosthesis Use and Accommodation Practices of People with Transtibial Amputation (2018)

ABSTRACT Introduction Practitioners typically rely on patient self-report for information about prosthesis use and limb volume accommodation. Electronic monitoring may provide a more accurate and easier means of collecting these data. Methods A novel low-profile sensor was used for 2 weeks to track when the limb was within the socket. Each participant also recorded daily prosthesis don times, doff times, and sock changes in a written log. Results Participants (n = 21) wore their prosthesis frequently, for approximately 14.1 hrs/day (interquartile range [IQR], 12.5–14.9), and doffed their prosthesis for 0.5 hr/day (IQR, 0.1–1.2). Of those participants who performed sock changes, participants most often performed sock changes 0.4 times per day (IQR, 0.3–1.0) and socket releases (temporary doffs) 1.3 times per day (IQR, 0.5–3.8). Measured and self-reported beginning-of-prosthesis day were not significantly different ( P = 0.002), whereas end-of-prosthesis day were significantly different ( P = 0.573). Conclusions The developed electronic monitor may improve recording of prosthesis use and monitoring of socket releases. Data collected in this study may serve as a starting point for characterizing socket wear and accommodation in people with limb loss.
On Thermal Performance of Seawater Cooling Towers (2010)

Seawater cooling towers have been used since the 1970s in power generation and other industries, so as to reduce the consumption of freshwater. The salts in seawater are known to create a number of operational problems, including salt deposition, packing blockage, corrosion, and certain environmental impacts from salt drift and blowdown return. In addition, the salinity of seawater affects the thermophysical properties that govern the thermal performance of cooling towers, including vapor pressure, density, specific heat, viscosity, thermal conductivity, and surface tension. In this paper, the thermal performance of seawater cooling towers is investigated using a detailed model of a counterflow wet cooling tower. The model takes into consideration the coupled heat and mass transfer processes and does not make any of the conventional Merkel approximations. In addition, the model incorporates the most up-to-date seawater properties in the literature. The model governing equations are solved numerically, and its validity is checked against the available data in the literature. Based on the results of the model, a correction factor that characterizes the degradation of the cooling tower effectiveness as a function of seawater salinity and temperature approach is presented for performance evaluation purposes.
Study of parity and time-reversal violation in neutron-nucleus interactions (1995)

The parity and time‐reversal symmetries can be studied in neutron‐nucleus interactions. Parity non‐conserving asymmetries have been observed for many p‐wave resonances in a compound nucleus and measurements were performed on several nuclei in the mass region of A∼100 and A∼230. The statistical model of the compound nucleus provides a theoretical basis for extracting mean‐squared matrix elements from the experimental asymmetry data, and for interpreting the mean‐squared matrix elements. The constraints on the weak meson‐exchange couplings calculated from the compound‐nucleus asymmetry data agree qualitatively with the results from few‐body and light‐nuclei experiments. The tests of time‐reversal invariance in various experiments using thermal, epithermal, and MeV neutrons are being developed.
Correction for Hydrophone Spatial Averaging Artifacts for Circular Sources (2020)

This article reports an investigation of an inverse-filter method to correct for experimental underestimation of pressure due to spatial averaging across a hydrophone sensitive element. The spatial averaging filter (SAF) depends on hydrophone type (membrane, needle, or fiber-optic), hydrophone geometrical sensitive element diameter, transducer driving frequency, and transducer F number (ratio of focal length to diameter). The absolute difference between theoretical and experimental SAFs for 25 transducer/hydrophone pairs was 7% ± 3% (mean ± standard deviation). Empirical formulas based on SAFs are provided to enable researchers to easily correct for hydrophone spatial averaging errors in peak compressional pressure ( p<sub>c</sub> ), peak rarefactional pressure ( p<sub>r</sub> ), and pulse intensity integral. The empirical formulas show, for example, that if a 3-MHz, F /2 transducer is driven to moderate nonlinear distortion and measured at the focal point with a 500- [Formula: see text] membrane hydrophone, then spatial averaging errors are approximately 16% ( p<sub>c</sub> ), 12% ( p<sub>r</sub> ), and 24% (pulse intensity integral). The formulas are based on circular transducers but also provide plausible upper bounds for spatial averaging errors for transducers with rectangular-transmit apertures, such as linear and phased arrays.
Tyrosine 474 of ZAP-70 Is Required for Association with the Shc Adaptor and for T-cell Antigen Receptor-dependent Gene Activation (1998)

The protein tyrosine kinase ZAP-70 plays a central role in T-cell activation. Following receptor engagement, ZAP-70 is recruited to the phosphorylated subunits of the T-cell antigen receptor (TCR). This event results in ZAP-70 activation and in association of ZAP-70 with a number of signaling proteins. Among these is the Shc adaptor, which couples the activated TCR to Ras. Shc interaction with ZAP-70 is mediated by the Shc PTB domain. The inhibitory effect of a Shc mutant containing the isolated PTB domain suggests that Shc interaction with ZAP-70 might be required for TCR signaling. Here, we show that a point mutation (Phe474) of the putative Shc binding site on ZAP-70, spanning tyrosine 474, prevented ZAP-70 interaction with Shc and the subsequent binding of Shc to phospho-zeta. Neither ZAP-70 catalytic activity nor the pattern of protein phosphorylation induced by TCR triggering was affected by this mutation. However expression of the Phe474 ZAP-70 mutant resulted in impaired TCR-dependent gene activation. ZAP-70 could effectively phosphorylate Shc in vitro. Only the CH domain, which contains the two Grb2 binding sites on Shc, was phosphorylated by ZAP-70. Both Grb2 binding sites were excellent substrates for ZAP-70. The data show that Tyr474 on ZAP-70 is required for TCR signaling and suggest that Shc association with ZAP-70 and the resulting phosphorylation of Shc might be an obligatory step in linking the activated TCR to the Ras pathway.
Biofilm Formation and Degradation of Commercially Available Biodegradable Plastic Films by Bacterial Consortiums in Freshwater Environments (2018)

We investigated biofilm formation on biodegradable plastics in freshwater samples. Poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBH) was covered by a biofilm after an incubation in freshwater samples. A next generation sequencing analysis of the bacterial communities of biofilms that formed on PHBH films revealed the dominance of the order Burkholderiales. Furthermore, Acidovorax and Undibacterium were the predominant genera in most biofilms. Twenty-five out of 28 PHBH-degrading isolates were assigned to the genus Acidovorax, while the other three were assigned to the genera Undibacterium and Chitinimonas. These results demonstrated that the order Burkholderiales in biofilms functions as a degrader of PHBH films.
Supplemental Figure 2 from Characterization of an Immunogenic Mutation in a Patient with Metastatic Triple-Negative Breast Cancer (2023)

&lt;p&gt;HLA typing data.&lt;/p&gt;
I212 Effect of Cellulose, Hemi-cellulose and Lignin Compositions in Woody and Grass Biomass on Pyrolysis Process and Gas Yield (2012)

This paper reports on the pyrolysis of various biomass materials. In particular, the primary yields of total volatiles, tar and non-condensable gases, together with the composition of non-condensable gases, are measured as a function of temperature. The results indicate that the pyrolysis process of wood and grass biomass (tar and gas evolution process) is greatly affected by the main composition (cellulose, hemicellulose and lignin) and the linear trends with atomic H/C ratio are observed in the tar yield, total volatile yield CO, CO_2 and CH_4 yields. The volatile yields of wood and grass biomass are predicted based only on the values of ultimate analysis of the biomass.
Quantum ballistic transport in a dual-gate Si transistor (1996)

By solving three-dimensional (3-D) Poisson and Schrodinger equations, we have shown that the formation of quantum dots are not very likely in the dual-gate Si transistor recently processed. The observed oscillations in the transconductance versus upper and lower gate voltages can be understood as elastic quantum ballistic transport from the source to the drain through the conducting channel. The importance of the fringing electric field effect and the quantum transport characteristics are to be emphasized in investigation and design of small size electronic devices.
Clinical image quality perception and its relation to NECR measurements in PET (2014)

Clinically perceived image quality in PET systems is positively and significantly related to NECR measured in patients. An optimal threshold for the R DW and R DBMI was defined in which clinical IQ is good to excellent in more than 90% of patients. With this data, it is possible to extrapolate technical as well as clinical image quality to other PET system and to predict clinical image perception.
Sensitizing cancer cells to immune checkpoint inhibitors by microbiota-mediated upregulation of HLA class I (2023)

Sensitizing cancer cells to immune checkpoint inhibitors by microbiota-mediated upregulation of HLA class I
Performance Analysis and Operating Limits of a Dual-Inverter Open-Winding IPMSM Drive (2019)

Operating capabilities of a dual-inverter open-winding interior permanent magnet synchronous motor (IPMSM) drive are investigated and compared with those of a conventional single-inverter drive in maximum torque per ampere (MTPA) and field-weakening (FW) regions. To predict the performance and operating limits of the drive systems with improved accuracy, the impact of saturation on inductances and permanent magnet (PM) flux linkage values are taken into account, and core, copper, friction and windage, and solid losses are considered in a wide speed range. Performance prediction is conducted using machine's electromagnetic parameters and losses that are obtained via finite element analysis, coupled with an optimization algorithm to find optimal operating points in MTPA and FW regions. The analytical findings are further validated against experimental results obtained from a 1-kW dual-inverter IPMSM motor drive.