gebhart/patrepeval huggingface dataset:
Faster Functional Warming with Cache Merging (2023)

Smarts-like sampled hardware simulation techniques achieve good accuracy by simulating many small portions of an application in detail. However, while this reduces the simulation time, it results in extensive cache warming times, as each of the many simulation points requires warming the whole memory hierarchy. Adaptive Cache Warming reduces this time by iteratively increasing warming to achieve sufficient accuracy. Unfortunately, each increases requires that the previous warming be redone, nearly doubling the total warming. We address re-warming by developing a technique to merge the cache states from the previous and additional warming iterations.
Nimesulide, a novel NSAID of the sulfonanilide class, inhibits PGE2 production by human chondrocytes without affecting proteoglycans synthesis (1997)

peer reviewed
Average modeling of a three-phase inverter for integration in a microgrid (2014)

This paper proposes average inverter model operating in two complementary modes suitable for microgrid simulation applications. Three phase voltage source inverter (VSI) connects to the microgrid through an LCL low pass filter and operates either in current controlled (CC) or voltage controlled (VC) mode. Models presented here take into account the nonlinear behavior of the switches, delays in the control loops, and the practical constraints. Models can simulate active and reactive power controls of the inverter in two different ways and also to estimate the low order harmonics of the output current. The performance of developed average models was verified by comparison of the simulation results between these models and detailed switching model of a 125 kW inverter.
Effects of dimerized lysozyme (KLP-602) on the cellular and humoral defence mechanisms in sheatfish (Silurus glanis): in vitro and in vivo study (1999)

International audience
Block copolymer self-assembly in selective solvents: Spherical micelles with segregated cores (1989)

A theory of micellization of AB diblock copolymer molecules in a selective solvent S is developed here. The micelles are assumed to have a completely segregated core region consisting only of the A block and a shell region consisting of the solvent S and the solvent compatible B block. The theory allows one to predict the critical micelle concentration, the micelle size distribution, the average aggregation number, as well as the core radius and the shell thickness of the micelle. The novel outcome of the present theory, in contrast to the treatments of micellization pioneered by de Gennes, Leibler, Orland, and Wheeler, and Noolandi and Hong, is its prediction that the solvent compatible B block plays an important role in determining the micellization behavior. The influence of the B block becomes relatively more prominent in systems where the solvent S constitutes a very good solvent for the B block. Further, scaling relations that are not system specific have been developed relating explicitly the micellar size parameters to the characteristics of the block copolymer and the solvent.
The Antinociceptive Effect of S-(+)-Ibuprofen in Rabbits (1995)

This study was designed to determine whether systemic absorption plays any role in the antinociceptive effect of epidural (EP) sodium S(+)-ibuprofen (IB). One week after surgical implantation of EP catheters, six rabbits were given EP injections with either normal saline (NS) 0.4 mL or IB 10 mg in 0.4 mL NS (Group 1) on separate days. Each animal was injected with IB 10 mg intravenously (IV) on another day. Six control rabbits (Group 2) had neither surgery nor any injection. Analgesic testing was performed using electric stimulation through two electrocardiogram (ECG) skin electrodes with built-in adhesive, attached to shaved hip areas using 50 V, 1 Hz, 3 ms, before and 0.5, 1, 2, and 3 h after injection in Group 1, and in similar times in controls. The 95% confidence intervals (CI) of the mean difference between baseline and maximal nociceptive response latency of all groups were compared using analysis of covariance (ANCOVA) adjusted for baseline measurements. This comparison covered all possible pairs among all groups. Significant antinociceptive effects were seen after EP IB but not after control or IV IB. Neither motor dysfunction nor evidence of systemic toxicity or neurotoxicity was observed in any animal. (Anesth Analg 1995;80:92-6)
Tunable spectral slicing filter utilizing sparse grating in Ti:LiNbO 3 (2009)

A new type of tunable guided-wave spectral slicing filter at the 1530nm wavelength regime is reported. The design allows the selection of equally spaced frequency channels and simultaneously produces nulls that are equally spaced between the selected channels. This makes it attractive for minimizing crosstalk in dense wavelength division multiplexing (DWDM) applications. The spectral selection of the filter is based on co-directional polarization coupling between transverse electric (TE) and transverse magnetic (TM) orthogonal modes in a waveguide by means of a static strain induced index grating. An etalon-like response results from the sparse arrangement of the grating sections as N individual coupling regions in tandem with equal spacing between their centers, yielding N-1 equally spaced nulls between adjacent selected frequencies. Adjustments of the resulting filtering function may be obtained by proper choice of coupling regions' lengths and spacing. Devices were fabricated using single mode channel waveguides formed by Ti diffusion on x-cut y-propagating LiNbO<sub>3</sub> substrates. Static strain from a periodically delineated surface film was used for making N = 6 polarization coupling regions. Electrode patterns centered about the optical waveguide and defined by liftoff were used to tune the filter electrooptically. Experimental results are in good agreement with design theory.
Re: Corporeal Plication For Surgical Correction Of Peyronie’S Disease, by G. R. Mufti, M. Aitchison, S. P. Bramwell, P. J. Paterson and R. Scott, J. Urol., 144: 281-283, 1990 (1993)

No AccessJournal of Urology1 Apr 1993Re: Corporeal Plication For Surgical Correction Of Peyronie’S Disease, by G. R. Mufti, M. Aitchison, S. P. Bramwell, P. J. Paterson and R. Scott, J. Urol., 144: 281-283, 1990 Daniel Yachia Daniel YachiaDaniel Yachia More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)36243-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Re: Corporeal Plication For Surgical Correction Of Peyronie’S Disease, by G. R. Mufti, M. Aitchison, S. P. Bramwell, P. J. Paterson and R. Scott, J. Urol., 144: 281-283, 1990." The Journal of Urology, 149(4), p. 869 © 1993 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited ByCordon B, Sundaram V, Hofer M, Kavoussi N, Scott J and Morey A (2018) Penile Plication as Salvage Strategy for Refractory Peyronie’s Disease DeformitiesUrology Practice, VOL. 4, NO. 2, (149-154), Online publication date: 1-Mar-2017.HELLSTROM W and REDDY S (2018) APPLICATION OF PERICARDIAL GRAFT IN THE SURGICAL MANAGEMENT OF PEYRONIE’S DISEASEJournal of Urology, VOL. 163, NO. 5, (1445-1447), Online publication date: 1-May-2000. Volume 149Issue 4April 1993Page: 869 Advertisement Copyright & Permissions© 1993 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Daniel Yachia More articles by this author Expand All Advertisement Loading ...
ChemInform Abstract: Asymmetric Allylation of Carbonyl Compounds via Organoboranes (2012)

Abstract Review: 198 refs.
Paralogous chemoreceptors mediate chemotaxis towards protein amino acids and the non‐protein amino acid gamma‐aminobutyrate (GABA) (2013)

The paralogous receptors PctA, PctB and PctC of Pseudomonas aeruginosa were reported to mediate chemotaxis to amino acids, intermediates of amino acid metabolism and chlorinated hydrocarbons. We show that the recombinant ligand binding regions (LBRs) of PctA, PctB and PctC bind 17, 5 and 2 l-amino acids respectively. In addition, PctC-LBR recognized GABA but not any other structurally related compound. l-Gln, one of the three amino acids that is not recognized by PctA-LBR, was the most tightly binding ligand to PctB suggesting that PctB has evolved to mediate chemotaxis primarily towards l-Gln. Bacteria were efficiently attracted to l-Gln and GABA, but mutation of pctB and pctC, respectively, abolished chemoattraction. The physiological relevance of taxis towards GABA is proposed to reside in an interaction with plants. LBRs were predicted to adopt double PDC (PhoQ/DcuS/CitA) like structures and site-directed mutagenesis studies showed that ligands bind to the membrane-distal module. Analytical ultracentrifugation studies have shown that PctA-LBR and PctB-LBR are monomeric in the absence and presence of ligands, which is in contrast to the enterobacterial receptors that require sensor domain dimers for ligand recognition.
Selective sulfonation and deuteration of free-base corroles (2002)

We show that, despite the 139 possible products, tris(pentafluorophenyl)corrole is sulfonated by H 2 SO 4 in quantitative yield to a 9:1 mixture of only the 2,17- and 3,17- isomers and that its deuteration by trifluoroacetic acid-d proceeds in the order of C 3,17 &gt; C 2,18 &gt;&gt; C 8,12 &gt; C 7,13 . These results add confidence to the feasibility of electrophilic substitution of corroles as a synthetic tool to many novel derivatives.
Proteome-wide changes in primary skin keratinocytes exposed to diesel particulate extract—A role for antioxidants in skin health (2019)

BackgroundSkin acts as a protective barrier against direct contact with pollutants but inhalation and systemic exposure have indirect effect on keratinocytes. Exposure to diesel exhaust has been linked to increased oxidative stress.ObjectiveTo investigate global proteomic alterations in diesel particulate extract (DPE)/ its vapor exposed skin keratinocytes.MethodsWe employed Tandem Mass Tag (TMT)-based proteomics to study effect of DPE/ DPE vapor on primary skin keratinocytes.ResultsWe observed an increased expression of oxidative stress response protein NRF2, upon chronic exposure of primary keratinocytes to DPE/ its vapor which includes volatile components such as polycyclic aromatic hydrocarbons (PAHs). Mass spectrometry-based quantitative proteomics led to identification 4490 proteins of which 201 and 374 proteins were significantly dysregulated (≥1.5 fold, p ≤ 0.05) in each condition, respectively.Proteins involved in cellular processes such as cornification (cornifin A), wound healing (antileukoproteinase) and differentiation (suprabasin) were significantly downregulated in primary keratinocytes exposed to DPE/ DPE vapor. These results were corroborated in 3D skin models chronically exposed to DPE/ DPE vapor. Bioinformatics analyses indicate that DPE and its vapor affect distinct molecular processes in skin keratinocytes. Components of mitochondrial oxidative phosphorylation machinery were seen to be exclusively overexpressed upon chronic DPE vapor exposure. In addition, treatment with an antioxidant like vitamin E partially restores expression of proteins altered upon exposure to DPE/ DPE vapor.ConclusionsOur study highlights distinct adverse effects of chronic exposure to DPE/ DPE vapor on skin keratinocytes and the potential role of vitamin E in alleviating adverse effects of environmental pollution.
Effects of vacuum-ultraviolet irradiation on copper penetration into low-k dielectrics under bias-temperature stress (2015)

The effects of vacuum-ultraviolet (VUV) irradiation on copper penetration into non-porous low-k dielectrics under bias-temperature stress (BTS) were investigated. By employing x-ray photoelectron spectroscopy depth-profile measurements on both as-deposited and VUV-irradiated SiCOH/Cu stacks, it was found that under the same BTS conditions, the diffusion depth of Cu into the VUV-irradiated SiCOH is higher than that of as-deposited SiCOH. On the other hand, under the same temperature-annealing stress (TS) without electric bias, the Cu distribution profiles in the VUV-irradiated SiCOH were same with that for the as-deposited SiCOH. The experiments suggest that in as-deposited SiCOH, the diffused Cu exists primarily in the atomic state, while in VUV-irradiated SiCOH, the diffused Cu is oxidized by the hydroxyl ions (OH−) generated from VUV irradiation and exists in the ionic state. The mechanisms for metal diffusion and ion injection in VUV irradiated low-k dielectrics are discussed.
Effects of administration of omega-3 fatty acids with or without vitamin E supplementation on adiponectin gene expression in PBMCs and serum adiponectin and adipocyte fatty acid-binding protein levels in male patients with CAD (2015)

Omega-3 fatty acids with or without vitamin E improve adiponectin levels in patients, without any significant changes in adiponectin gene expression. This nutritional intervention may prevent complications in patients with CAD because of increased adiponectin levels.
Volumetric blood flow measurement with color Doppler ultrasonography: the importance of visual clues (1993)

Volumetric flow rates were obtained in an in vivo canine pulsatile flow model using color Doppler ultrasonography (CDUS) and timed collection (TC) over a range which included laminar and turbulent flow. CDUS demonstrated increasing flow disturbance as flow rates increased, with effects on velocity profile, diameter measurements, and flow symmetry. Data comparing CDUS and TC showed marked differences in laminar flow (regression: slope = 1.02; r2 = 0.93; mean error, 11%) and nonlaminar flow (slope = 0.53; r2 = 0.78; mean error, 26%). Assigning the angle of insonation precisely was crucial to measurement accuracy. CDUS quantitates volumetric blood flow with a reasonable degree of accuracy under laminar flow conditions. Visual clues provided by CDUS can help avoid errors associated with deviations from laminar flow.
Heterogeneous Enantioselective Catalyzed Carbonyl‐ and Imino‐Ene Reactions using Copper Bis(Oxazoline) Zeolite Y (2004)

A recovery discovery: A simple pathway for the synthesis of α-hydroxy and α-amino carbonyl compounds with good yields and high enantioselection is provided by the first heterogeneously catalyzed enantioselective carbonyl-ene and imino-ene reactions. The catalyst is a bis(oxazoline)-modified CuH zeolite Y (Cu-HY)system (see scheme; Rox=CH3,H; Rbrg=Ph,C(CH3)3), which can easily be recovered and reused.
A 3.6 GHz dual modulus prescaler IC using optimal pseudomorphic HEMT structure on Si substrates (2002)

A dual modulus divide-by-128 or 129 prescaler IC was fabricated using 0.35 /spl mu/m gate-length HEMT DCFL technology on a Si substrate. We optimized the HEMT epitaxial structure so that it consisted of a Si-doped InAlGaAs-AlGaAs (5/5 nm) strained layer superlattice (SLS), an InGaAs pseudomorphic channel layer, an SLS buffer layer and a GaAs buffer layer grown by MOVPE. Our prescaler IC on a Si substrate gives 3.6 GHz/9.8 mW at a supply voltage of 1.5 V.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Communicating the sum of sources in a 3-sources/3-terminals network; revisited (2010)

We consider the problem of multicasting sums over directed acyclic networks with unit capacity edges. A set of source nodes s <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">i</sub> observe independent unit-entropy source processes X <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">i</sub> and want to communicate Σ X <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">i</sub> to a set of terminals t <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">j</sub> . Previous work on this problem has established necessary and sufficient conditions on the s <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">i</sub> -t <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">j</sub> connectivity in the case when there are two sources or two terminals (Ramamoorthy '08), and in the case of three sources and three terminals (Langberg-Ramamoorthy '09). In particular the latter result establishes that each terminal can recover the sum if there are two edge disjoint paths between each s <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">i</sub> -t <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">j</sub> pair. In this work, we provide a new and significantly simpler proof of this result, and introduce techniques that may be of independent interest in other network coding problems.
Kinematic alignment technique for total hip and knee arthroplasty (2018)

Conventional techniques for hip and knee arthroplasty have led to good long-term clinical outcomes, but complications remain despite better surgical precision and improvements in implant design and quality.Technological improvements and a better understanding of joint kinematics have facilitated the progression to 'personalized' implant positioning (kinematic alignment) for total hip (THA) and knee (TKA) arthroplasty, the true value of which remains to be determined.By achieving a true knee resurfacing, the kinematic alignment (KA) technique for TKA aims at aligning the components with the physiological kinematic axes of the knee and restoring the constitutional tibio-femoral joint line frontal and axial orientation and soft-tissue laxity.The KA technique for THA aims at restoring the native 'combined femoro-acetabular anteversion' and the hip's centre of rotation, and occasionally adjusting the cup position and design based on the assessment of the individual spine-hip relation.The key element for optimal prosthetic joint kinematics (hip or knee) is to reproduce the femoral anatomy.The transverse acetabular ligament (TAL) is the reference landmark to adjust the cup position. Cite this article: <i>EFORT Open Rev</i> 2018;3:98-105. DOI: 10.1302/2058-5241.3.170022.
The crystal structure determination of the crystalline layered silicic acid H-RUB-18 (2002)

Abstract The layer silicate H-RUB-18 (chemical compo-sition: Si 4 O 7 (OH) 2 ) was prepared by ion exchange from the parent material Na-RUB-18. The high degree of structural disorder typical for this material precluded a classical structure analysis based on diffraction data only. Nevertheless, a detailed picture of the structure was obtained by a step by step process using a combination of complementary methods: Crystal chemical considerations and solid state NMR spectroscopy allowed to establish a rough model of the structure which was optimized by forcefield molecular dynamics (MD) simulations. A subsequent Rietveld refinement in space group I 4 1 / amd confirmed the model consisting of a sequence of pseudo tetragonal silicate layers with an intra-layer repeat unit a = 7.38 Å and inter-layer distances of c = 7.44 Å. The main type and degree of disorder was analyzed by the simulation of various stacking sequences of rigid silicate layers which served as the building blocks. The random displacement of consecutive layers is accompanied by a slight distortion of the layers as indicated by an additional density functional theory (DFT) energy minimization calculation in triclinic symmetry. The given displacement and distortion allow for the formation of hydrogen bonds between the terminal OH groups necessary for the stabilization of the structure. The concept of a structure analysis presented in this paper may be suitable as a guide line to be applied to many other disordered materials.
The microwave processability of semicrystalline polymers (1993)

Abstract The overall objective of these studies was to investigate the relationship between polymer structure and microwave absorptivity. In this paper, the microwave processing of semicrystalline polymers such as poly(ether ether ketone) (PEEK), nylons, and poly(ethylene terephthalate) (PET), via a cylindrical resonance wave cavity and a rectangular standing wave applicator is described. These polymeric materials were irradiated in low power (&lt; 50W) electric fields at 2.45 GHz. Silicone flexible molds were necessary for improved processing of nylons and PEEK at temperatures below their T c Rapid heating rates were observed between the glass transition temperature, T g , and the melting temperature, T m , for all these polymers provided that T c was exceeded. Both dynamic mechanical thermal analysis (DMTA) and dielectric thermal analysis (DETA) spectra were utilized to predict the heating phenomena between amorphous and semicrystalline materials and to explain the rapid crystallizing rate of PEEK. above its glass transition temperature. Correlations were drawn between (a) the apparent activation energy and the critical temperature ( T c ) and (b) the shape of the dielectric spectra at 2.45 GHz and its shape in kHz region.
Nanoscopic mechanism of Cu precipitation at small-angle tilt boundaries in Si (2015)

We investigate copper (Cu) precipitation at small-angle tilt boundaries on (220) in Czochralski-grown p-type silicon (Si) ingots using transmission electron microscopy, atom probe tomography, and ab initio calculations. In the initial stage of precipitation, Cu atoms agglomerate along the boundaries, forming coherent layers (less than about 2 nm thick) of ${\mathrm{Cu}}_{3}\mathrm{Si}$ with a body-centered-cubic structure in a metastable state ($a=0.285$ nm). As the layers thicken, they become semicoherent with misfit dislocations on the (220) interphase boundaries, reducing coherency strains. Subsequently, the metastable layers convert into incoherent polyhedrons of orthorhombic ${\ensuremath{\eta}}^{\ensuremath{'}\ensuremath{'}}\text{\ensuremath{-}}{\mathrm{Cu}}_{3}\mathrm{Si}$ in the equilibrium state, forming interphase boundaries on {112} in Si. These results are similar to the Cu precipitation processes found in metallic alloys: the formation of Guinier-Preston zones followed by a conversion into the equilibrium $\ensuremath{\theta}$ phase.
07291 Summary – Scientific Visualization (2008)

Scientific visualization (SV) is concerned with the use of computer-generated images to aid the understanding, analysis and manipulation of data. Since its beginning in the early 90's, the techniques of SV have aided scientists, engineers, medical practitioners, and others in the study of a wide variety of data sets including, for example, high performance computing simulations, measured data from scanners (CAT, MR, confocal microscopy), internet traffic, and financial records. One of the important themes being nurtured under the aegis of Scientific Visualization is the utilization of the broad bandwidth of the human sensory system in steering and interpreting complex processes and simulations involving voluminous data sets across diverse scientific disciplines. Since vision dominates our sensory input, strong efforts have been made to bring the mathematical abstraction and modeling to our eyes through the mediation of computer graphics. This interplay between various application areas and their specific problem solving visualization techniques was emphasized in the proposed seminar.