gebhart/patrepeval huggingface dataset:
Reconstruction of two-dimensional distribution function of defects in dielectrics based on TSD data (2002)

Thermally stimulated current spectroscopy (TSCS) due to its simplicity and informativity plays the leading role among the investigation methods of electrically active defects (EADs) in high-resistance materials. In the case of disordered dielectrics, the EADs are characterized by a two-dimensional distribution function of relaxators G(W,/spl omega/), where W is the activation energy and /spl omega/ is the frequency factor. In this paper a hybrid numerical method is proposed for defining G(W,/spl omega/) from the experimentally derived TSD current dependence on temperature.
Photonic Integration on Silicon: Conquering the Last Centimeter (2007)

Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text L. Kimerling, "Photonic Integration on Silicon: Conquering the Last Centimeter," in Integrated Photonics and Nanophotonics Research and Applications / Slow and Fast Light, OSA Technical Digest (CD) (Optica Publishing Group, 2007), paper JMB1. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Stokes Vector Scattering induced by Nonlinear Depolarization of Light in Fiber (2020)

We report the experimental observation of SOP scattering in Stokes space caused by nonlinear depolarization (NLDP) of light in fiber. In addition to our previous characterizations of NLDP by SOP speed histograms and Stokes vector spectra, we measure SOP scattering angles. For trans-Pacific propagation distances these angles range within a few degrees.
Propagation of finite amplitude sound through turbulence (2003)

Pestorius and Blackstock [‘‘Propagation of finite amplitude noise,’’ Finite-amplitude wave effects in fluids, Proceedings of the 1973 International Symposium on Nonlinear Acoustics, edited by L. J. Bjo/rno/, 1973] developed a method to simulate the propagation of finite amplitude noise in a tube. The method separates the effects of nonlinear distortion and absorption and diffraction. The nonlinear steepening of an arbitrary waveform is performed in the time domain. The absorption and diffraction effects are implemented in the frequency domain. This method has been used widely for finite amplitude wave propagation. Lipkens and Blanc-Benon [‘‘Propagation of finite-amplitude sound through turbulence: a geometrical acoustics approach,’’ C. R. Acad. Sci. Paris, Ser. II&amp;lt;th&amp;gt;b 320, 477–484 (1995)] used the Pestorius model to simulate the propagation of N waves through turbulence. Linear geometrical acoustics is used to trace rays through individual realizations of a turbulent field. A nonlinear transport equation describes the propagation of sound through turbulence. The equation is solved using the Pestorius algorithm. The results indicate that the equivalent nonlinear distortion after propagation through turbulence is always less than that for the homogeneous case. In addition, the effect of a random velocity field is more pronounced that that of a random temperature field.
Dapagliflozin and New York Heart Association functional class in heart failure with mildly reduced or preserved ejection fraction: the DELIVER trial (2022)

Among symptomatic patients with HF and LVEF >40%, treatment with dapagliflozin provided clinical benefit irrespective of baseline NYHA class and was associated with early and sustained improvements in NYHA class over time.
Artificial baroreflex system restores volume tolerance in the absence of native baroreflex (2011)

The arterial baroreflex stabilizes arterial pressure by modulating the mechanical properties of cardiovascular system. We previously demonstrated that the baroreflex impairment makes the circulatory system extremely sensitive to volume overload and predisposes to pulmonary edema irrespective of left ventricular systolic function. To overcome the volume intolerance, we developed an artificial baroreflex system by directly stimulating the carotid sinus nerves in response to changes in arterial pressure. The artificial baroreflex system precisely reproduced the native arterial pressure response and restored physiological volume buffering function. We conclude that the artificial baroreflex system would be an attractive tool in preventing pulmonary edema in patients with impaired baroreflex function.
Ostwald Ripening of Clusters during Protein Crystallization (2010)

Contrary to classical nucleation theory, protein crystals can nucleate via a two-step process in which the molecular arrangement of the ordered solid phase is preceded by nucleation of a dense amorphous phase. We study the growth of these precrystalline clusters in lysozyme using a combination of dynamic light scattering, optical microscopy, and microfluidics. Clusters display Ostwald ripening growth kinetics but deviate from this trend after nucleation of the crystal phase. This behavior arises from the metastable relationship between clusters and the ordered solid and is explained numerically using a population balance model.
EDA for autonomous behavior assurance (2020)

Autonomous systems are self-governed and self-adaptive systems that must additionally comply with high assurance correctness and safety criteria. Such autonomous systems cannot be tested and verified in the traditional design process. While all systems hardware and software components can be implemented as usual, test and verification only cover the autonomous system functionality, but do not include the goal-driven autonomous behavior in all possible circumstances. This autonomous behavior is a primary design target. Thus, autonomous systems pose a number of emerging challenges and opportunities to the field of electronic design automation (EDA). Examples include specification of (evolving) requirements involving components and their interaction, defining different assurance levels for bounded operational environments, synthesis of mechanisms to guideline diagnosis and rigorously monitor systems integration after deployment.
EFFECT OF HEMOGLOBIN VESICLES ON AGONIST-INDUCED PLATELET ACTIVATION IN VITRO (2003)

Hemoglobin vesicles (HbV), a type of liposome-encapsulated hemoglobin (LEH), have been recently developed as an artificial oxygen carrier. The efficacy of HbV has been demonstrated in the transfusion of HbV into rodent models of hemorrhagic shock. It is important to evaluate the compatibility of HbV with human blood cells. We examined the effects of HbV on human platelet activation in vitro by estimating the platelet release reaction and expression of platelet surface activation markers in the presence or absence of agonists. HbV concentration in the reaction volume was prepared at 20% or 40%. Preincubation of platelet-rich plasma (PRP) with HbV had no adverse effects on RANTES or serotonin release from platelets. Preincubation of whole blood with HbV also had no effects on exposure of P-selectin on platelets. However, binding of PAC-1, a monoclonal antibody that detects the activation-dependent conformational change of αIIbβ3 to platelets, was amplified by preincubation of whole blood with HbV in the presence of relatively low concentration of ADP. These results suggest that HbV enhances the binding of PAC-1 to platelets. The clinical meaning of this increased binding of PAC-1 needs to be addressed.
Protein Pathway Activation Mapping of Brain Metastasis from Lung and Breast Cancers Reveals Organ Type Specific Drug Target Activation (2011)

Brain metastases are the most common fatal complication of systemic cancer, especially of lung (40-50%) and breast (20-30%) cancers. In this era of personalized therapy, there is a critical need to uncover the signaling architecture of brain metastases; however, little is known about what signaling pathways are activated in the context of the brain microenvironment. Using a unique study set of 42 brain metastases from patients with breast or nonsmall cell lung cancer (NSCLC), the phosphorylation/activation states of 128 key signaling proteins involved in cancer signaling were measured in laser capture microdissected tumor epithelium using reverse phase protein microarray (RPMA) technology. Distinct pathway activation subgroups from both breast and lung metastases were underpinned by, among others, ERBB2, AKT, mTOR, EGFR, SMAD, and ERK-p38 signaling. Breast cancer metastases showed significantly (p < 0.05) higher activation of the c-ERBB2/IGFR-AKT pathway network compared to NSCLC metastases, whereas NSCLC metastases to the brain exhibited higher relative levels of many members of the EGFR-ERK signaling network. Protein pathway activation mapping using RPMA revealed both the heterogeneity of signaling networks in brain metastases that would require a prior stratification to targeted therapies as well as the requirement of direct analysis of the metastatic lesion.
ChemInform Abstract: Synthesis of an Esterase‐Sensitive Cyclic Prodrug of a Model Hexapeptide Having Enhanced Membrane Permeability and Enzymic Stability Using a 3‐(2′‐Hydroxy‐4′,6′‐dimethylphenyl)‐3,3‐Dimethylpropionic Acid Promoiety (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Comment on ’’Existence of H2−, a relatively long-lived doubly charged negative atomic hydrogen ion’’ (1976)

An experimental method for distinguishing between two conflicting hypotheses [R. Schnitzer and M. Anbar, J. Chem. Phys. 64, 4332 (1976) and W. Aberth, J. Chem. Phys. 65, 2466, (1976)] concerning the possible existence of H2− is given.(AIP)
Partial Breast Reconstruction Using Various Oncoplastic Techniques for Centrally Located Breast Cancer (2014)

In centrally located breast cancer, oncoplastic surgery considering breast size and resection volume is safe and provides appropriate aesthetic outcomes. Therefore, our method is advisable for breast cancer patients who elect to conserve their breasts and retain a natural breast shape.
An Autonomous Sensor and Telemetry System for Low-Level pCO2 Measurements in Seawater (1999)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionORIGINAL ARTICLEThis notice is a correctionAn Autonomous Sensor and Telemetry System for Low-Level pCO2 Measurements in SeawaterMary Beth Tabacco, Mahesh Uttamlal, Mariann McAllister, and David R. WaltCite this: Anal. Chem. 1999, 71, 7, 1483Publication Date (Web):February 27, 1999Publication History Published online27 February 1999Published inissue 1 April 1999https://pubs.acs.org/doi/10.1021/ac991580phttps://doi.org/10.1021/ac991580pcorrectionACS PublicationsCopyright © 1999 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views301Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (15 KB) Get e-Alertsclose Get e-Alerts
ANALYSIS OF THE BRASSICA ´A´ AND ´C´ GENOMES AND COMPARISON WITH THE GENOME OF ARABIDOPSIS THALIANA (2006)

The growing availability of Brassica genomic sequence data presents the opportunity of conducting a detailed analysis into the relationships between the Brassica A and C genomes as well as a comparison between these two Brassica genomes and the complete genome sequence of the model plant Arabidopsis thaliana. Through the Multinational Brassica Genome Project, there are a growing number of Brassica rapa (A genome) BAC end sequences being produced, with the aim of delivering the end sequences of 110,000 BACs by 2005. We have developed a computational tool for the comparative mapping of these Brassica BACs onto the Arabidopsis genome. The tool electronically maps BACs onto Arabidopsis by aligning the end sequences for each BAC with regions of the Arabidopsis genome sequence, followed by filtering for BAC ends aligning in an inverse orientation within a specified genomic distance (<500,000 bp). Furthermore, we have compared the publicly available B. oleracea (C genome) shotgun sequences both with the Arabidopsis genome and the B. rapa BAC end sequences. An analysis of the resulting data provides the opportunity to identify regions of conservation between the three genomes, regions of gene duplication, as well as regions of conserved synteny between B. rapa and Arabidopsis. The results provide an insight into the comparative structure of the three genomes and assist in the efficient selection of candidate B. rapa BACs to be sequenced as part of the Multinational Brassica Genome Project.
Local Conformational Transition of Hydrogenobacter thermophilus Cytochrome c552 Relevant to Its Redox Potential, (2007)

In order to elucidate the molecular mechanisms responsible for the apparent nonlinear behavior of the temperature dependence of the redox potential of Hydrogenobacter thermophilus cytochrome c552 [Takahashi, Y., Sasaki, H., Takayama, S. J., Mikami, S., Kawano, S., Mita, H., Sambongi, Y., and Yamamoto, Y. (2006) Biochemistry 45, 11005-11011], its heme active site structure has been characterized using variable-temperature and -pressure NMR techniques. The study revealed a temperature-dependent conformational transition between protein structures, which slightly differ in the conformation of the loop bearing the Fe-bound axial Met residue. The heme environment in the protein structure which arises at lower temperature was found to be more polar, as a result of the altered orientation of the loop with respect to the heme due to its conformational change, than that arising at higher temperature. The present study demonstrated the importance of the structural and dynamic properties of the polypeptide chain in close proximity to the heme for redox regulation of the protein.
Supplementary Material for: An Analysis of Histone Modifications in Relation to Sex-Specific Chromatin Organization in the Mealybug Maconellicoccus hirsutus (2010)

The male-specific heterochromatization of the paternal genome, observed in coccids, is an example of both genomic imprinting and differential regulation of homologous chromosomes. We observed a highly nuclease-resistant chromatin (NRC) organization of a part of the paternal genome in males of <i>Maconellicoccus hirsutus</i> as reported earlier in <i>Planococcus lilacinus</i>. The nuclease resistance of NRC is correlated with nuclear matrix association and is lost when NRC is dissociated from the matrix. We carried out a comparative analysis of epigenetic modifications of histones in matrix associated chromatin of male and female mealybugs by ELISA. We detected H3K27me3, H4K20me3, H3K9me2 and H3K4me3 in both males and females and observed significant enrichment of H3K27me3 in the nuclear matrix of males compared to that of females. To further examine the presence of NRC in the germ line, nuclei were sorted based on chromatin compaction. The analysis of sorted nuclei indicates the presence of NRC in nuclei with different DNA content including the haploid nuclei from males. We discuss these results in the light of the presence of NRC exclusively in male nuclei and the retention of the maternal genome in sperm nuclei of mealybugs.
Big data analytics frameworks for the influence of gut microbiota on the development of tic disorder (2022)

The association between gut microbiota and psychiatric disorders has received increasing research attention. Meanwhile, big data analysis has been utilized in many filed including business, human healthcare analysis, <i>etc</i>. The primary objective of this article was to provide insights into Big Data Analytics (BDA) to clarify the association between gut microbiota and TD (Tic disorder). Specifically, we investigated the recent studies related to gut microbiota composition differences in patients with TD compared to health people. We searched on PubMed and Embase (Ovid) databases for relevant published articles until June 15, 2021. A total of 78 TD and 62 health control stool samples were examined. Case-control design was applied in all the studies. No consensus was evident in α-diversity and β-diversity. The abundance of phyla <i>Bacteroidetes</i> and <i>Firmicutes</i> was predominant at the taxa level. Gut microbiota taxonomic differences were found between TD cases and controls, though inconsistently across studies. Further studies are needed to reveal the underlying pathophysiology of TD and correlation between TD and gut microbiota composition.
Effect of Edible Coatings and Other Surface Treatments on Pericarp Color of Thai Lychee Cultivars (2007)

Although it has long been known that practicing a motor task with one limb can improve performance with the limb opposite, the mechanisms remain poorly understood. Here we tested the hypothesis that improved performance with the untrained limb on a fastest possible (i.e. ballistic) movement task depends partly on cortical circuits located ipsilateral to the trained limb. The idea that crossed effects, which are important for the learning process, might occur in the 'untrained' hemisphere following ballistic training is based on the observation that tasks requiring strong descending drive generate extensive bilateral cortical activity. Twenty-one volunteers practiced a ballistic index finger abduction task with their right hand, and corticospinal excitability was assessed in two hand muscles (first dorsal interosseus, FDI; adductor digiti minimi, ADM). Eight control subjects did not train. After training, repetitive transcranial magnetic stimulation (rTMS; 15 min at 1 Hz) was applied to the left (trained) or right (untrained) motor cortex to induce a 'virtual lesion'. A third training group received sham rTMS, and control subjects received rTMS to the right motor cortex. Performance and corticospinal excitability (for FDI) increased in both hands for training but not control subjects. rTMS of the left, trained motor cortex specifically reduced training-induced gains in motor performance for the right, trained hand, and rTMS of the right, untrained motor cortex specifically reduced performance gains for the left, untrained hand. Thus, cortical processes within the untrained hemisphere, ipsilateral to the trained hand, contribute to early retention of ballistic performance gains for the untrained limb.
Faulty Neural Networks (2023)

This study aims to investigate the response of the nervous system to injury through experiments using a neural network model trained with the MNIST dataset [1]. Multiple experiments are performed to examine the relationship between neural network damage and accuracy. How the damaged network can restore its functionality or accuracy with the aid of another neural network is also investigated. By analyzing these results, a better understanding of the nervous system’s ability to respond to injury and adapt to changes in neural networks can be gained.
Adding shaft angle measurement to generator protection and monitoring (2013)

Traditional protective relays for generators have used electrical quantities (current and voltage) to measure the condition of the machine. It has long been recognized that information about the machine can also be used in protection. New technology makes it possible to combine mechanical and electrical inputs. This paper examines the use of rotor shaft angle measurement in a generator combined with the electrical angle of the output voltage. This provides for the direct measurement of system conditions that could only be estimated or approximated with earlier technologies. Some of the protection, control, and situational awareness applications now possible include the following: Subsynchronous resonance detection and mitigation : Out-of-step detection : Machine parameter estimation and validation : Transient stability control. One significant improvement over previous applications that provided these functions is that no physical connection or significant modification of the shaft is necessary. As power grids operate closer to critical stability limits, the ability to measure and control precise shaft angle will provide the high reliability necessary for electric power.
Electrochemical CO2 to CO reduction at high current densities using a nanoporous gold catalyst (2020)

We report on integrating ultrathin monolithic nanoporous gold (npAu) catalyst coatings for CO2 reduction in a large electrode area (25 cm2) electrochemical membrane reactor with gas diffusion electrodes at 100 mA/cm2. The CO Faraday efficiency increases with increasing thickness, from 65% to 75% and 80% for 1, 5, and 10 layers of npAu leaves where each npAu leaf layer is 100 nm thick. For the one npAu leaf layer configuration, this corresponds to an extremely high CO current density of 955 A/g gold thus demonstrating the potential for commercial applications.
Elektromagnetisch basierte Instrumentennavigation für CT-gesteuerte Interventionen: Evaluation am Phantom und ex-vivo Model (2008)

Ziele: Evaluation eines auf elektromagnetischem Tracking der Instrumentenspitze basierenden Navigationssystems für CT-gesteuerte Interventionen an einem Lendenwirbelsäulen-Phantom und am Tierkadaver. Methode: An einem in Gelwachs eingebetteten Lendenwirbelsäulen(LWS)-Phantom sowie zwei Schweine-Kadavern wurden mithilfe eines elektromagnetisch basierten Navigationssystems (CAPPA IRAD EMT, CAS innovations, Erlangen, Deutschland) je 20 Punktionen der LWS-Facettengelenke sowie je 10 Punktionen der LWS-Bandscheiben durchgeführt. Zunächst wurde ein hochaufgelöster CT Datensatz zur Interventionsplanung aufgenommen (64×0,6mm, 120kV, 165 mAseff.). Die überlappend rekonstruierten Bilddatensätze (1mm Schichtdicke; 0,7mm Inkrement) wurden an das Navigationssystem übertragen. Anschließend erfolgte mithilfe der Navigations-Software die Planung der Punktionswege. Entlang der geplanten Trajektorien wurden die Facettengelenke und Bandscheiben mit einer elektromagnetisch navigierten Koaxialnadel punktiert. Nach Entfernung des Trokars wurde über die noch liegende Hohlnadel ein Draht zur Markierung des Punktionskanals vorgeschoben. Anhand einer anschließenden CT-Untersuchung wurde die Abweichung zwischen Drahtspitze und Zielstruktur sowie die Punktionslänge bestimmt. Ergebnis: Insgesamt wurden 60 elektromagnetisch navigierte Punktionen durchgeführt. Mit Ausnahme einer Punktion am Kadaver wurden alle Bandscheiben erfolgreich punktiert bei einem mittleren Punktionsweg von 90±5mm (Phantom) bzw. 72±12mm (Kadaver). Die mittleren Abweichungen bei Punktion der Facettengelenke betrugen 0,3±0,7mm im Phantom und 2,5±2,0mm im Kadaver bei mittleren Punktionswegen von 54±11mm (Phantom) bzw. 50±14mm (Kadaver). Schlussfolgerung: Die elektromagnetisch basierte Instrumentennavigation ist auch in der CT mit einer ausreichend hohen Genauigkeit möglich. Weiterführende Patienten-Studien sind notwendig um die klinische Anwendbarkeit zu zeigen.