gebhart/patrepeval huggingface dataset:
The Tuscarora War: Indians, Settlers, and the Fight for the Carolina Colonies (2015)

Book Review| January 01 2015 The Tuscarora War: Indians, Settlers, and the Fight for the Carolina Colonies The Tuscarora War: Indians, Settlers, and the Fight for the Carolina Colonies. By La Vere, David. (Chapel Hill: University of North Carolina Press, 2013. 262 pp., prologue, introduction, illustrations, maps, note from the author, notes, bibliography, acknowledgments, index. $30.00 cloth.) Bradford J. Wood Bradford J. Wood Search for other works by this author on: This Site Google Ethnohistory (2015) 62 (1): 192–193. https://doi.org/10.1215/00141801-2821878 Cite Icon Cite Share Icon Share Facebook Twitter LinkedIn MailTo Permissions Search Site Citation Bradford J. Wood; The Tuscarora War: Indians, Settlers, and the Fight for the Carolina Colonies. Ethnohistory 1 January 2015; 62 (1): 192–193. doi: https://doi.org/10.1215/00141801-2821878 Download citation file: Zotero Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search Books & JournalsAll JournalsEthnohistory Search Advanced Search The text of this article is only available as a PDF. Copyright 2015 by American Society for Ethnohistory2015 Article PDF first page preview Close Modal You do not currently have access to this content.
Fresnel particle tracing in three dimensions using diffraction phase microscopy (2007)

We have developed a novel experimental technique for tracking small particles in three dimensions with nanometer accuracy. The longitudinal positioning of a micrometer-sized particle is determined by using the Fresnel approximation to describe the transverse distribution of the wavefront that originated in the particle. The method utilizes the high-sensitivity quantitative phase imaging capability of diffraction phase microscopy recently developed in our laboratory. We demonstrate the principle of the technique with experiments on Brownian particles jittering in water both in bulk and in the vicinity of a boundary. The particles are localized in space within an error cube of 20 nm x 20 nm x 20 nm for a 33 Hz acquisition rate and 20s recording time.
ChemInform Abstract: The Hydrothermal Synthesis of Tetragonal Tungsten Bronze‐Based Catalysts for the Selective Oxidation of Hydrocarbons. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
PTENpred: A Designer Protein Impact Predictor for PTEN-related Disorders (2016)

Connecting a genotype with a phenotype can provide immediate advantages in the context of modern medicine. Especially useful would be an algorithm for predicting the impact of nonsynonymous single-nucleotide polymorphisms in the gene for PTEN, a protein that is implicated in most human cancers and connected to germline disorders that include autism. We have developed a protein impact predictor, PTENpred, that integrates data from multiple analyses using a support vector machine algorithm. PTENpred can predict phenotypes related to a human PTEN mutation with high accuracy. The output of PTENpred is designed for use by biologists, clinicians, and laymen, and features an interactive display of the three-dimensional structure of PTEN. Using knowledge about the structure of proteins, in general, and the PTEN protein, in particular, enables the prediction of consequences from damage to the human PTEN gene. This algorithm, which can be accessed online, could facilitate the implementation of effective therapeutic regimens for cancer and other diseases.
Laser (2011)

Laser ist ein Kunstwort und steht als Abkürzung für „Light Amplification by Stimulated Emission of Radiation“. Es geht also um die Lichtverstärkung durch eine Spezialform der Abstrahlung, nämlich der induzierten Emission. Erstmalig konnte diese auf Einstein zurückgehende Idee im Jahr 1960 in Form eines Rubin-Lasers realisiert werden. Um das Prinzip zu verstehen, werden wir im ersten Unterkapitel zunächst die Grundlagen besprechen. Danach werden die wichtigsten Lasertypen vorgestellt, sowie eine Reihe von Laseranwendungen. Hier konnten zwei Spezialisten für Unterkapitel zu diesem Buch gewonnen werden (Griebsch: Lasermaterialbearbeitung; Möller: Laser in der Medizin). Abgeschlossen wird das Kapitel mit einem Abschnitt über Lasersicherheit.
What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira (2016)

Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread, neglected and emerging zoonotic disease. While whole genome analysis of individual pathogenic, intermediately pathogenic and saprophytic Leptospira species has been reported, comprehensive cross-species genomic comparison of all known species of infectious and non-infectious Leptospira, with the goal of identifying genes related to pathogenesis and mammalian host adaptation, remains a key gap in the field. Infectious Leptospira, comprised of pathogenic and intermediately pathogenic Leptospira, evolutionarily diverged from non-infectious, saprophytic Leptospira, as demonstrated by the following computational biology analyses: 1) the definitive taxonomy and evolutionary relatedness among all known Leptospira species; 2) genomically-predicted metabolic reconstructions that indicate novel adaptation of infectious Leptospira to mammals, including sialic acid biosynthesis, pathogen-specific porphyrin metabolism and the first-time demonstration of cobalamin (B12) autotrophy as a bacterial virulence factor; 3) CRISPR/Cas systems demonstrated only to be present in pathogenic Leptospira, suggesting a potential mechanism for this clade's refractoriness to gene targeting; 4) finding Leptospira pathogen-specific specialized protein secretion systems; 5) novel virulence-related genes/gene families such as the Virulence Modifying (VM) (PF07598 paralogs) proteins and pathogen-specific adhesins; 6) discovery of novel, pathogen-specific protein modification and secretion mechanisms including unique lipoprotein signal peptide motifs, Sec-independent twin arginine protein secretion motifs, and the absence of certain canonical signal recognition particle proteins from all Leptospira; and 7) and demonstration of infectious Leptospira-specific signal-responsive gene expression, motility and chemotaxis systems. By identifying large scale changes in infectious (pathogenic and intermediately pathogenic) vs. non-infectious Leptospira, this work provides new insights into the evolution of a genus of bacterial pathogens. This work will be a comprehensive roadmap for understanding leptospirosis pathogenesis. More generally, it provides new insights into mechanisms by which bacterial pathogens adapt to mammalian hosts.
Laboratory Experiments in Economics: The Implications of Posted- Price Institutions (2001)

This outstanding collection spanning three decades comprises a superb selection of Charles R. Plott’s work in experimental economics. Market Institutions and Price Discovery contains papers which define problems, create laboratory methodology and produce the first results in many areas of experimental economics.
Photoactive polyamideimides synthesized by the polycondensation of azo-dye diamines and rosin derivative (2000)

New rosin-based photoactive polyamideimides (PAI-a and PAI-b) with a large second-order nonlinear optical coefficient and photoinduced birefringence were synthesized by the polycondensation of rosin–maleic anhydride adduct (RMA) with azo-dye diamines, 2-(2-{ethyl-[4-(4-nitrophenylazo)phenyl]aminoethoxy)benzene-1,4-diamine (4a) or 2-(2-{ethyl-[4-(4-methylsulfonylphenylazo)phenyl]amino}ethoxy)benzene-1,4-diamine (4b). Due to the bulky alicyclic structure of the rosin, these polymers were highly soluble in organic solvents and could easily be processed by spin-coating into thin films of high optical quality. Fabricated polymer films were very smooth, tough, adhesive to the substrate, and optically clear. Second-order nonlinear optical coefficients (d33) of the corona-poled PAI-a and PAI-b films were 83 and 54 pm/V, respectively, at the fundamental wavelength of 1064 nm. Birefringences as high as 0.072 for PAI-a and 0.035 for PAI-b could be induced and erased repeatedly by the irradiation of linearly polarized and circularly polarized 532-nm light, respectively. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 79: 687–695, 2001
Multi-GPU based evaluation and analysis of prehistoric ice cores using OpenCL (2015)

The analysis of prehistoric ice cores is a well established instrument in the field of climate research. Until recently, common methods were often based on the analysis of carbon dioxide and methane concentrations. The use of computed tomography based 3-D reconstructions for the evaluation and analysis of prehistoric ice cores yields the possibility to improve the accuracy of age determination by an order order of magnitude, from hundreds of years to decades. This, in turn, allows the improvement of the underlying model of the climatic development over the last several hundreds of thousands of years. The use of 3-D volumes allows a much more detailed analysis with respect to the size, amount, distribution and connectivity of air bubbles in the ice cores as a new climatic proxy. In this setting, we present a GPU-based approach for the efficient evaluation and analysis of air bubbles using OpenCL. As the raw data size can grow up to 10 TB per meter of ice core, we focus on a distributable and scalable approach, which is based on component labeling and can be scaled to multiple-GPUs using OpenCL.
Delaying Effect of a Wine Lactobacillus plantarum Strain on the Coloration and Xanthylium Pigment Formation Occurring in (+)-Catechin and (−)-Epicatechin Wine Model Solutions (2010)

This article reports for the first time on the capacity of a wine Lactobacillus plantarum strain to alter the oxidative coloration of (+)-catechin and (-)-epicatechin hydroethanolic wine model solutions in the presence of Fe(2+) as catalyst. The time course of color development and pigment formation in the solutions was tracked over 42 days. The pigments formed were characterized as xanthylium structures regardless of the flavanol isomer present in the solution. The solutions supplied with Lactobacillus plantarum RM71 were oxidized at a slower rate, and consequently, its final color was less than that in the controls. The formation of both (+)-catechin and (-)-epicatechin-derived xanthylium pigments was also delayed over time in the presence of the bacterium compared to their respective cell-free controls. The delaying effects provided by L. plantarum on the oxidative coloration and the generation of xanthylium-derived pigments were more pronounced for the (-)-epicatechin than for the (+)-catechin model solutions. In view of these results and given that L. plantarum is naturally present in winemaking and generally recognized as a safe microorganism, the potential application of this bacterium as an antibrowning agent for wine is now opened.
Multi-biometric cohort analysis for biometric fusion (2008)

Biometric matching decisions have traditionally been made based solely on a score that represents the similarity of the query biometric to the enrolled biometric(s) of the claimed identity. Fusion schemes have been proposed to benefit from the availability of multiple biometric samples (e.g., multiple samples of the same fingerprint) or multiple different biometrics (e.g., face and fingerprint). These commonly adopted fusion approaches rarely make use of the large number of non-matching biometric samples available in the database in the form of other enrolled identities or training data. In this paper, we study the impact of combining this information with the existing fusion methodologies in a cohort analysis framework. Experimental results are provided to show the usefulness of such a cohort-based fusion of face and fingerprint biometrics.
Determination of the electronic density of states near buried interfaces: Application to Co/Cu multilayers (1996)

High-resolution ${\mathit{L}}_{3}$ x-ray absorption and emission spectra of Co and Cu in Co/Cu multilayers are shown to provide unique information on the occupied and unoccupied density of d states near buried interfaces. The d bands of both Co and Cu interfacial layers are shown to be considerably narrowed relative to the bulk metals, and for Cu interface layers the d density of states is found to be enhanced near the Fermi level. The experimental results are confirmed by self-consistent electronic structure calculations. \textcopyright{} 1996 The American Physical Society.
Abstract 16650: Transcriptional Profiling of Single Human Heart Cells Reveals Subtypes of Ventricular Cardiomyocytes (2016)

Regenerative strategies have the potential to transform the treatment of heart failure. Their success relies on a detailed molecular-genetic understanding of human cardiac cell development. Single-...
Competing Risk of Death When Comparing Tibial Implant Types in Total Knee Arthroplasty (2016)

This study examines the clinical relevance of the competing risk of death in total knee arthroplasty.
Seamless Multi-Access Edge Computing Application Handover Experiments (2021)

Multi-Access Edge Computing (MEC) is one of the fundamental technologies committed to satisfy the requirements targeted by 5G and beyond networks, such as low latency and massive communications. Nevertheless, deploying a large-scale MEC infrastructure will require a huge investment that should be minimized by optimizing the resources at edge locations, and to use centralized datacenters when possible. Thus, automated orchestration is essential for implementing mechanisms that deploy applications at the best location and even that relocate them, when necessary, to satisfy the Quality of Service (QoS) requirements. In this paper we describe an architecture for this purpose, which we have implemented in an experiment that demonstrates how Open Source MANO (OSM) can automate the relocation of a video processing application that helps drivers to remember the latest traffic sign viewed. Our proposal also includes two new components: the first one maintains the state of the applications when they are deployed at a new location, and the second one allows OSM managing the Open Network Edge Services Software (OpenNESS) edge platform. Finally, we elaborate on open challenges in MEC platforms.
z2z: Discovering Zeroconf Services Beyond Local Link (2007)

The Zeroconf technology, better known as Apple Bonjour, is one of the most prominent solutions for service discovery in local area networks. Zeroconf uses multicast to attain its goal of eliminating configurations in service discovery. The multicast-based design, however, makes it difficult for Zeroconf services to reach beyond the local link. This makes the technology unsuitable for certain discovery scenarios which would otherwise be good candidates. This paper presents the Zeroconf-to-Zeroconf Toolkit (z2z), our first attempt to realize a hybrid architecture that combines the simplicity of Zeroconf with the scalability of DHT-based peer-to-peer networks. Our z2z connects multiple Zeroconf subnets using OpenDHT. By doing so, it extends the reach of existing Zeroconf-enabled applications beyond the local link. Furthermore, it provides a framework on which to build a global service discovery solution based on Zeroconf.
Silica Monoliths Templated on L3 Liquid Crystal (2005)

Dimensionally stable, optically clear, highly porous (approximately 65% of the apparent volume), and high surface area (up to 1400 m(2)/g) silica monoliths were fabricated as thick disks (0.5 cm) by templating the isotropic liquid crystalline L(3) phase with silica through the hydrolysis and condensation of a silicon alkoxide and then removing the organic constituents by supercritical ethanol extraction. The L(3) liquid crystal is a stable phase formed by the cosurfactants cetylpyridinium chloride monohydrate and hexanol in HCl(aq) solvent. Extracted 0.5 cm thick disks exhibited a low ratio of scattered to transmitted visible light (1.5 x 10(-)(6) at 22 degrees from the surface normal). The degree of silica condensation in the monoliths was high, as determined by (29)Si NMR measurements of Q(3) and Q(4) peak intensities (0.53 and 0.47, respectively). As a result, the extracted and dried monoliths were mechanically robust and did not fracture when infiltrated by organic solvents. Photoactive liquid monomers were infiltrated into extracted silica monoliths and polymerized in situ, demonstrating the possible application of templated silica to optical storage technology.
Resource Banking An Energy-efficient, Run-time Adaptive Processor Design Technique (2011)

From the earliest and simplest scalar computation engines to modern superscalar out-oforder processors, the evolution of computational machinery during the past century has largely been driven by a single goal: performance. In today’s world of cheap, billion-plus transistor count processors and with an exploding market in mobile computing, a design landscape has emerged where energy efficiency, arguably more than any other single metric, determines the viability of a processor for a given application. The historical emphasis on performance has left modern processors bloated and over provisioned for everyday tasks in the hope that during computationally intensive periods some performance improvement will be observed. This work explores an energy-efficient processor design technique that ensures even a highly over provisioned out-of-order processor has only as many of its computational resources active as it requires for efficient computation at any given time. Specifically, this paper examines the feasibility of a dynamically banked register file and reorder buffer with variable banking policies that enable unused rename registers or reorder buffer entries to be voltage gated (turned off) during execution to save power. The impact of bank placement, turn-off and turn-on policies as well as rail stabilization latencies for this approach are explored for high-performance desktop and server designs as well as low-power mobile processors
Inherited mutations in DNA repair genes in men with metastatic castration-resistant prostate cancer. (2016)

5009 Background: Inherited mutations in genes that regulate DNA repair processes such as BRCA1 and BRCA2 associate with increased risks of developing lethal prostate cancer (PC), and with response to poly-ADP ribose polymerase (PARP) inhibition and platinum chemotherapy. While the prevalence of such mutations in men with localized PC unselected for family predisposition is insufficient to warrant routine testing, the frequency of germline DNA repair gene (DRG) mutations in men with metastatic prostate cancer (mPC) is not established. Methods: We recruited men with mPC (n = 569) through five IRB-approved studies enrolling across seven institutions designed to ascertain molecular aberrations in mPC. Men were unselected for family history of cancer and were documented to have mPC based on a biopsy of a metastatic site. We isolated germ-line DNA from blood lymphocytes, saliva, or tissue uninvolved with cancer and used multiplex sequencing assays to assess germline mutations in 20 DRGs associated with autosomal dominant cancer predisposition syndromes. Results: Sixty-six deleterious DRG germline mutations were identified in 65 men (11.4%), including BRCA2 (n = 29, 5.1%), ATM (n = 10, 1.8%), CHEK2 (n = 7, 1.2%), BRCA1 (n = 5, 0.9%), PALB2 (n = 3, 0.5%), RAD51D (n = 3, 0.5%), ATR (n = 2, 0.3%) and 1 man each with mutation in FAM175A, GEN1, MRE11A, MSH2, MSH6, RAD51C, and NBN. One patient had mutation in ATM and CHEK2. Overall, the frequency of germline DRG mutations in mPC significantly exceeded the 5% frequency identified in localized PC (n = 499; p < 0.001) which included men with high-risk PC, and 3.1% in the Exome Aggregation Consortium (ExAC) database, which includes individuals with cancer (n = 60,706; p< 0.005). Conclusions: The identification of a germline aberration in a DNA repair pathway gene has implications for treatment selection in view of the potential for therapeutic responses to PARP inhibitors and platinum chemotherapy, and also for identifying families at risk for cancer predisposition. These results suggest that men with mPC, regardless of family history of cancer, should be considered for germline genetic testing of DNA repair genes.
Potential Function of Exogenous Vimentin on the Activation of Wnt Signaling Pathway in Cancer Cells (2016)

Cancer cell signaling, growth, morphology, proliferation and tumorigenic potential are largely depending on the signaling molecules present naturally in the tumor microenvironment and the identification of key molecules that drive the tumor progression is critical for the development of new modalities for the prevention of tumor progression. High concentrations of vimentin in the blood of cancer patients have been reported, however the function of blood circulating vimentin remains unknown. Here, we investigated the functional role of exogenously supplemented vimentin on colon cancer cells and examined the Wnt Signaling activation and cancer cell invasion. Vimentin when supplemented to the cancer cells remained bound to the surface of the cancer cells. Furthermore, bound vimentin activates Wnt signaling pathway as detectable by increased β-catenin accumulation in the nucleus with concomitant activation of β-catenin-dependent transcription of Wnt signaling downstream targets. Functionally, there was an increase in the rate of cellular invasion in these cancer cells upon binding with vimentin. Our results thus suggest that free vimentin in the tumor microenvironment acts as a positive regulator of the β-catenin signaling pathway, thus providing a basis for cancer invasive properties.
Antibiotic-tolerant Staphylococcus aureus Biofilm Persists on Arthroplasty Materials (2016)

Antibiotic-tolerant biofilm suggests a mechanism behind the poor results in irrigation and débridement for acute TKA PJI.
Prospects for and barriers to a fungal vaccine (2007)

Vaccination is a desirable strategy to prevent life-threatening fungal infections. Candidiasis is the most common invasive fungal infection, and promising vaccine targets are nearing clinical testing to prevent such infections. One barrier to developing antifungal vaccines is the perceived risk of blunted immune responses in at-risk patients. However, vaccines stimulate effective immune responses even in highly immunocompromised patients. The biggest barrier to development of fungal vaccines is the lack of available capital to translate discoveries made at the bench into biologics used at the bedside. Nevertheless, vaccines targeting invasive fungal infections are an extremely promising avenue of research and development. It is desirable that additional sources of capital be made available to academic scientists to facilitate development of such vaccines.