gebhart/patrepeval huggingface dataset:
Physiological Bases of Across‐Environment and Environment‐Specific Responses for Grain Yield in Maize Hybrids Obtained from a Full Diallel Mating Design (2017)

ABSTRACT Genotype × environment interaction explains a proportion of variation for crop yield performance often higher than the genotypic effect, becoming a major impediment to genetic progress. In this study, a crop model of yield determination in combination with three‐mode principal component analysis (PCA) was used to analyze genotype × environment × attribute interaction. A full diallel of six maize ( Zea mays L.) inbred lines was grown in 10 environments in Argentina. The first environment component associated with the common genotype and attribute pattern across environments revealed that the main numerical determinant of plant grain yield (PGY) was kernel weight and not kernel number per plant (KNP). The second environment component established the importance of genotype × year interaction for anthesis‐silking interval (ASI), KNP, and PGY when water deficit prevailed during the critical period of yield determination and revealed a lack of association between ASI and ear growth rate during this period. The three‐mode PCA described the specific patterns of hybrid performance across environments, revealing physiological processes that separate inbred lines that contribute to drought tolerance, but at the expense of limiting PGY under well‐watered conditions. The use of a crop growth model allowed interpretation of the effects of environment conditions on main physiological determinants of grain yield, exposing the effects of water supply/demand ratio as a possible driver of differential performance of inbred lines.
Induction of smectic layering in nematic liquid crystals using immiscible components IV. The effect of bulky lateral carboxyl substituents on the thermotropic behaviour of 2,5-bis[4-(n-perfluoroheptyloctyloxy)benzoyloxy]toluene (2001)

Abstract Bulky lateral carboxylate substituents were introduced at the benzylic position of 2,5-bis[4-(n-perfluoroheptyloctyloxy)benzoyloxy]toluene by esterification of the corresponding benzyl bromide with potassium carboxylates. In spite of the bulky lateral substituents, none of the 2,5-bis[4-(n-perfluoroheptyloctyloxy)benzoyloxy]benzyl carboxylates exhibit a nematic mesophase in addition to, or instead of, the smectic mesophases. All of the crystalline and SmC-SmA transition temperatures and, with the exception of the 9-anthracene carboxylate derivative, all of the isotropization temperatures of the resulting 2,5-bis[4-(n-perfluoroheptyloctyloxy)benzoyloxy]benzyl carboxylates are lower than those of the parent toluene compound. The SmC-SmA transition decreases the most, thereby stabilizing the SmA mesophase. In most cases, the SmC mesophase is destabilized from an enantiotropic to a monotropic mesophase. There is no correlation between any of the transition temperatures and the size of the lateral substituent.
Research Spotlight: The University of Kansas High-Throughput Screening Laboratory. Part I: Meeting Drug-Discovery Needs in the Heartland of America with Entrepreneurial Flair (2011)

The University of Kansas High-Throughput Screening (KU HTS) core is a state-of-the-art drug-discovery facility with an entrepreneurial open-service policy, which provides centralized resources supporting public- and private-sector research initiatives. The KU HTS core applies pharmaceutical industry project-management principles in an academic setting by bringing together multidisciplinary teams to fill critical scientific and technology gaps, using an experienced team of industry-trained researchers and project managers. The KU HTS proactively engages in supporting grant applications for extramural funding, intellectual-property management and technology transfer. The KU HTS staff further provides educational opportunities for the KU faculty and students to learn cutting-edge technologies in drug-discovery platforms through seminars, workshops, internships and course teaching. This is the first instalment of a two-part contribution from the KU HTS laboratory.
Saxagliptin: A potential doping agent? A randomized, double‐blinded, placebo‐controlled, and crossover pilot study in young active men (2022)

Neuropeptide Ys (NPYs) contribute to sympathetic-adreno stimulation: NPY1-36 potentiates the effects of catecholamines (CATs), whereas NPY3-36 inhibits CAT release. We sought to investigate whether inhibiting dipeptidyl-peptidase-4 (DPP4), cleaving NPY1-36 into NPY3-36, leads to increased NPY1-36 potentiating effects and reduced NPY3-36 inhibitory effects on CATs, thereby improving endurance performance. Seven male participants (age 27 ± 3 years, BMI 23.1 ± 2.4 kg/m<sup>2</sup> ) performed time-to-exhaustion cycling exercise at 95% of peak power output with either placebo, or saxagliptin, a DPP4 inhibitor. Oxygen consumption (V̇O<sub>2</sub> ), heart rate variability, NPY1-36, NPY3-36, catecholamines, and lactate were measured at several time points before, during, and after exercise. With saxagliptin, DPP4 activity (12.7 ± 1.6 vs. 0.2 ± 0.3 U/L, p = 0.001; d = 10.7) was decreased at rest, while NPY3-36 (1.94 ± 0.88 vs. 0.73 ± 0.22 pm; p < 0.001; d = 2.04) decreased and NPY1-36 increased during exercise (2.64 ± 2.22 vs. 4.59 ± 2.98 pm; p < 0.01; d = 0.19). CATs were unchanged. Time-to-exhaustion was 32% higher with saxagliptin. The difference in time-to-exhaustion between placebo and saxagliptin was correlated with NPY1-36 differences (R = 0.78, p < 0.05). Peak V̇O<sub>2</sub> and other cardio-respiratory values were not different, whereas peak NPY concentrations were higher with saxagliptin. DPP4 blockade improved performance, increased NPY1-36, and decreased NPY3-36 concentrations which may have potentiating effects on the influences of CATs. However, DPP4 is involved in many different actions, thus NPYs are one group of factors that may underly its performance-enhancing effects; further studies are required to determine the exact mechanisms.
Woodchuck hepatitis and hepatocellular carcinoma: Correlation of histologic with virologic observations (1981)

The livers of 33 captive woodchucks were examined histologically in 30 biopsy and 10 autopsy specimens and the findings were correlated with serum determinations for woodchuck hepatitis virus (WHV), surface antigen (WHsAg) and antibody (anti-WHs), and WHV DNA and DNA polymerase. The liver appeared normal in all 3 serum-negative animals, 7 of 16 with indeterminate WHV status, and 1 of 4 with anti-WHs, but not in 10 animals with WHsAg, WHV DNA, and DNA polymerase. Mild hepatic inflammation was found in 7 woodchucks with indeterminate status, 4 with anti-WHs, and 2 with each marker of WHV infection. Significant inflammation was found in 2 of indeterminate status and 4 with every marker, whereas more severe lesions (2 of chronic active type) occurred, almost always in autopsy specimens, in 8 animals with every marker. Eight of 10 animals with all markers had orcein-positive inclusions (Shikata's technique) and 6 had hepatocellular carcinoma associated with acute and chronic hepatic inflammation and, usually, neoplastic nodules in the noncarcinomatous parenchyma. Features distinguishing the woodchuck lesion from human hepatitis B disease were: association of carcinoma with acute hepatic inflammation (but not with cirrhosis) and DNA polymerase in the serum; transition to carcinoma from neoplastic nodules; conspicuous plasma-cellular reaction of hepatic inflammation, and hematopoietic cells in the tumor. Significant hepatic lesions in the woodchucks were regularly associated with serum WHsAg, WHV DNA, and DNA polymerase. In contrast to man, hepatocellular carcinoma in woodchucks was regularly associated with these markers of active viral replication. The nature of the orcein-positive inclusions requires elucidation, although they may assist in screening for similar viruses in other species. The woodchuck may help in the study of the relation between hepatocellular carcinoma and hepatitis B, including the possibility of cocarcinogenic factors.
Galaxy LIMS for next-generation sequencing (2013)

The code and documentation are available at http://tron-mainz.de/tron-facilities/computational-medicine/galaxy-lims/
Mobile agents: the next generation in distributed computing (2002)

Mobile agents are programs that can move through a network under their own control, migrating from host to host and interacting with other agents and resources on each. We argue that these mobile, autonomous agents have the potential to provide a convenient, efficient and robust programming paradigm for distributed applications, particularly when partially connected computers are involved. Partially connected computers include mobile computers such as laptops and personal digital assistants as well as modem connected home computers, all of which are often disconnected from the network. We describe the design and implementation of our mobile agent system, Agent Tcl, and the specific features that support mobile computers and disconnected operation. These features include network sensing tools and a docking system that allows an agent to transparently move between mobile computers, regardless of when the computers connect to the network.
Should your specification language be typed (1999)

Most specification languages have a type system. Type systems are hard to get right, and getting them wrong can lead to inconsistencies. Set theory can serve as the basis for a specification language without types. This possibility, which has been widely overlooked, offers many advantages. Untyped set theory is simple and is more flexible than any simple typed formalism. Polymorphism, overloading, and subtyping can make a type system more powerful, but at the cost of increased somplexity, and such refinements can never attain the flexibility of having no types at all. Typed formalisms have advantages, too, stemming from the power of mechanical type checking. While types serve little purpose in hand proofs, they do help with mechanized proofs. In the absence of verificaiton, type checking can catch errors in specifications. It may be possible to have the best of both worlds by adding typing annotations to an untyped specification language. We consider only specification languages, not programming languages.
Design and Fabrication of Mid-IR Guided Mode Resonance Filters (2012)

This paper summarizes design and fabrication results for Mid-IR Guided Mode Resonance filters based on Hexagonal and Rectangular arrays for use at 2.8 um. The devices are fabricated in Quartz substrates with Hafnium Dioxide.
Presence of simian virus 40 sequences in malignant mesotheliomas and mesothelial cell proliferations (2000)

Malignant mesotheliomas (MMs) are pleural-, pericardial-, or peritoneal-based neoplasms usually associated with asbestos exposure. Mesothelial cells are biphasic and may give rise to epithelial and sarcomatous MMs. In addition, benign or atypical proliferations of mesothelial cells may occur in response to many stimuli. There have been recent reports of simian virus 40 (SV40) DNA large T antigen (Tag) sequences in pleural MMs. To further understand the relationship between SV40, MMs, and mesothelial proliferations, we studied 118 MMs from multiple sites in Germany and North America, including 93 epithelial pleural, 14 sarcomatous or mixed pleural MMs, and 11 peritoneal MMs. In 12 pleural MMs, adjacent noninvasive tumor foci were identified and studied separately. Information about asbestos exposure (detailed history and/or microscopic examination for asbestos bodies) was available from 43 German patients. In addition, 13 examples of reactive mesothelium and 20 lung cancers from the United States were tested. DNA was extracted from frozen tumor and adjacent nontumorous tissues or after microdissection of archival formalin-fixed, paraffin-embedded microslides. Two rounds of PCR were performed with primers SVFor 3 and SVRev, which amplify a 105 bp region specific for SV40 Tag. The specificity of the PCR product was confirmed in some cases by sequencing. Our major findings were: 1) Specific SV40 viral sequences were present in 57% of epithelial invasive MMs, of both pleural and peritoneal origin. No significant geographic differences were found, and frozen and paraffin-embedded tissues were equally suitable for analysis. 2) There was no apparent relationship between the presence of SV40 sequences and asbestos exposure. 3) SV40 sequences were present in the surface (noninvasive) components of epithelial MMs. 4) SV40 sequences were not detected in MMs of sarcomatous or mixed histologies. 5) Viral sequences were present in two of 13 samples (15%) of reactive mesothelium. 6) Lung cancers lacked SV40 sequences, as did non-malignant tissues adjacent to MMs. Our findings demonstrate the presence of SV40 sequences in epithelial MMs of pleural and peritoneal origin and their absence in tumors with a sarcomatous component. Viral sequences may be present in reactive and malignant mesothelial cells, but they are absent in adjacent tissues and lung cancers. J. Cell. Biochem. 76:181–188, 1999. © 1999 Wiley-Liss, Inc.
Lensing properties of rotational gas flow: erratum (2019)

This erratum includes additional references relevant to rotational gas flow negative lenses that were omitted in Appl. Opt.57, 9392 (2018)APOPAI0003-693510.1364/AO.57.009392.
Mesh Quality Improvement based on Subdivision and Simplification (2005)

本論文では, 三角形メッシュの品質に依存する幾何・数値演算処理の安定性や精度の向上を目的とした, 頑強なメッシュ品質改善手法を提案する. 提案法は, メッシュ接続性操作自由度向上のための細分化と, 品質改善度評価に基づくメッシュ簡略化により, 入力の低品質メッシュの面分形状歪を減少し, 面分粗密を一様化するものであり, 数値的評価とFEMへ応用によりその有効性を示す.
Intracavity Phase Modulation for Phase Noise and Supermode Noise Spur Suppression in Mode-locked Lasers (2009)

Using intracavity active phase modulation, we have verified the theory of Haus and Rana and realized timing jitter reduction from 304fs to 150fs integrated to Nyquist frequency on a 10.24 GHz actively mode-locked pulse train.
Retinal expression, regulation, and functional bioactivity of prostacyclin-stimulating factor (2000)

Prostacyclin-stimulating factor (PSF) acts on vascular endothelial cells to stimulate the synthesis of the vasodilatory molecule prostacyclin (PGI2). We have examined the expression, regulation, and hemodynamic bioactivity of PSF both in whole retina and in cultured cells derived from this tissue. PSF was expressed in all retinal cell types examined in vitro, but immunohistochemical analysis revealed PSF mainly associated with retinal vessels. PSF expression was constitutive in retinal pericytes (RPCs) but could be modulated in bovine retinal capillary endothelial cells (RECs) by cell confluency, hypoxia, serum starvation, high glucose concentrations, or inversely by soluble factors present in early vs. late retinopathy, such as TGF-beta, VEGF, or bFGF. In addition, RPC-conditioned media dramatically increased REC PGI2 production, a response inhibited by blocking PSF with a specific antisense oligodeoxynucleotide (ODN). In vivo, PGI2 increased retinal blood flow (RBF) in control and diabetic animals. Furthermore, the early drop in RBF during the initial weeks after inducing diabetes in rats, as well as the later increase in RBF, both correlated with levels of retinal PSF. RBF also responded to treatment with RPC-conditioned media, and this effect could be partially blocked using the antisense PSF ODN. We conclude that PSF expressed by ocular cells can induce PGI2, retinal vascular dilation, and increased retinal blood flow, and that alterations in retinal PSF expression may explain the biphasic changes in RBF observed in diabetes.
Sufficient conditions used in admittance selection for planar force-guided assembly (2003)

Admittance control approaches show significant promise in providing reliable force-guided assembly. An important issue in the development of these approaches is the specification of an appropriate admittance control law. This paper identifies procedures for selecting the appropriate admittance to achieve reliable planar force-guided assembly for single-point contact cases. A set of conditions that are imposed on the admittance matrix is presented. These conditions ensure that the motion that results from contact reduces part misalignment. We show that for bounded misalignment, if the conditions are satisfied for a finite number of contact configurations, the system ensures that force guidance is achieved for all intermediate configurations.
Life Cycle Inventory analysis of prospective insect based feed production in West Africa (2017)

While the concept of insect based feeds (IBFs) promises great potential, especially in developing countries, the sustainability performance of IBF production remains widely underexplored. Drawing on experimental data from rearing trials in West Africa, three different insect production systems were modelled ex-ante. The generic models served as a basis to analyse and compare the process performances of different IBF production systems using Musca domestica and Hermetia illucens reared on different substrates. The results show that the input efficiency in the production of IBF is largely determined by the quality of rearing substrates, the larval development time and the employed inoculation practises, i.e. the method by which eggs or larvae are added to rearing substrates. The H. illucens system ranked highest for conversion efficiency (substrate input per IBF output), but showed substantially higher inputs in labour, fossil energy and output of wastewater. M. domestica systems operated at lower conversion efficiencies, which resulted in higher outputs of residue substrates, together with higher emissions, land requirements, built infrastructure and water. By offering full disclosure of generic inventory data, this study provides data and inspiration for prospect research and development activities and offers a reference to future life cycle assessments (LCAs) on IBF.
REPORTE CORTO/SHORT REPORT - PASSIVE IMMUNE GLOBULIN THERAPY AND ITS POTENTIAL FOR REDUCING VIRAL BURDEN (1995)

no abstract
Function of Oxygen Resistance Proteins in the Anaerobic, Sulfate-Reducing Bacterium Desulfovibrio vulgaris Hildenborough (2002)

Two mutant strains of Desulfovibrio vulgaris Hildenborough lacking either the sod gene for periplasmic superoxide dismutase or the rbr gene for rubrerythrin, a cytoplasmic hydrogen peroxide (H(2)O(2)) reductase, were constructed. Their resistance to oxidative stress was compared to that of the wild-type and of a sor mutant lacking the gene for the cytoplasmic superoxide reductase. The sor mutant was more sensitive to exposure to air or to internally or externally generated superoxide than was the sod mutant, which was in turn more sensitive than the wild-type strain. No obvious oxidative stress phenotype was found for the rbr mutant, indicating that H(2)O(2) resistance may also be conferred by two other rbr genes in the D. vulgaris genome. Inhibition of Sod activity by azide and H(2)O(2), but not by cyanide, indicated it to be an iron-containing Sod. The positions of Fe-Sod and Sor were mapped by two-dimensional gel electrophoresis (2DE). A strong decrease of Sor in continuously aerated cells, indicated by 2DE, may be a critical factor in causing cell death of D. vulgaris. Thus, Sor plays a key role in oxygen defense of D. vulgaris under fully aerobic conditions, when superoxide is generated mostly in the cytoplasm. Fe-Sod may be more important under microaerophilic conditions, when the periplasm contains oxygen-sensitive, superoxide-producing targets.
Respiratory Motion and Correction Simulation Platform for Coronary MR Angiography (2012)

This paper describes a simulation platform for use in the quantitative assessment of different respiratory motion correction techniques in Coronary MR angiography (CMRA). The simulator incorporates acquisition of motion parameters from heart motion tracking and applies it to a deformable heart model. To simulate respiratory motion, a high-resolution 3-D coronary heart reference image is deformed using the estimated linear transformation from a series of volunteer coronal scout scans. The deformed and motion-affected 3-D coronary images are used to generate segmented k-space data to represent MR data acquisition affected by respiratory motion. The acquired k-space data are then corrected using different respiratory motion correction methods and converted back to image data. The resulting images are quantitatively compared with each other using image-quality measures. Simulation experiment results are validated by acquiring CMRA scans using the correction methods used in the simulation.
Origins of high radiative efficiency and wideband emission from InAs quantum dots (2007)

Origins of high radiative efficiency and wideband emission from InAs quantum dots (QDs) were studied experimentally and theoretically. Radiative efficiency was found to depend strongly on the absence of large nonradiative islands. Theoretical calculations were performed to determine the combined effects of QD size and its fluctuation on the energy range. Good agreement between the theoretical and experimental results was obtained. Recognizing that high output power and large optical bandwidth are key figures of merit for QD superluminescent diodes (SLDs), we believe that the findings from our work will be beneficial for those working on QD-SLDs.
On the Synthesis and Luminescence of Red LED Phosphors Based Upon Garnet Hosts (2006)

Abstract not Available.
Design and Characterization of Microelectromechanical System Flow Sensors Using Silicon Nanowires (2011)

Cantilever structures were reported to be used for flow sensing purposes. Herein, we present silicon nanowire (SiNW) based cantilever flow sensor. Five cantilever flow sensors with different depths are modeled and simulated (fluid-structure) with water flow velocity from 50 cm/s to 200 cm/s. SiNW is embedded in the cantilever as piezoresistive transducer at the anchor, and a maximum resistance change of 11.2 % is obtained. Based on the results, increasing depth will not only contributes to lager cantilever deformation at fixed flow velocity, but also improves its sensitivity. However when the depth become larger to certain degree, this effect tends to saturate.
The Use of Phospholipid Fatty Acid Analysis to Estimate the Changes in Microbial Community Structure during Wood Decay in Forests (2008)

土壌微生物群集構造の解析に広く用いられているリン脂質脂肪酸（PLFA）分析法を木材の腐朽過程に応用し，スギ林または広葉樹林でのスギ及びコナラ供試材の分解にともなう微生物群集構造の変化について比較検討した。クラスター分析の結果，PLFA組成に基づく微生物群集構造は試験地の植生に関わらず，埋土した供試材の樹種の違いによって2つのグループに分類された。コナラ材は，両植生共に埋土初期から真菌類指標の脂肪酸の割合が高く，腐朽期間が長くなるにつれグラム陽性菌指標の脂肪酸が増加する傾向が見られ，これら微生物グループのバイオマスと木材腐朽率の間には有意な正の相関が見られた。一方，スギ材では，腐朽の進行に伴って真菌，グラム陽性菌，放線菌などの指標脂肪酸の増加が見られたが，真菌類バイオマスと木材腐朽率との間には相関関係が認められず，スギ材の腐朽には細菌類や放線菌類の関与が比較的大きいものと推定された。
Visual Servo for Fast Glass Handling by Industrial Robot with Large Sensor Latency and Low Sampling Rate (2017)

In the protective glass manufacturing industry for cell phones, the raw glass pieces need to be ground to the desired thickness with a grinder, which requires precise glass handling by human workers leading to a bottleneck in the production line. A low cost glass loading system with an industrial robot and web cameras is proposed to support human workers. Due to the hardware limitations, the precision and speed cannot be guaranteed. A two step approach is implemented to overcome these limitations. The glass is detected with non-linear geometry regression in data acquired by a web camera. After being picked up, the glass is placed accurately into the desired equally sized slot with an image-based visual servo and a dual-rate Unscented Kalman Filter.