gebhart/patrepeval huggingface dataset:
An evaluation of the electrostatic shielded induction motor: a solution for rotor shaft voltage buildup and bearing current (2002)

This paper evaluates a new induction motor, the electrostatic shielded induction motor (ESIM). An ESIM reduces rotor shaft voltages to levels below the bearing lubricant's electric field intensity breakdown level and offers one solution to accelerated bearing wear caused by fluting induced by pulse width modulated (PWM) inverters. The paper begins by reviewing shaft voltages and the resulting bearing currents when operated on PWM voltage source inverters. An example of bearing fluting is shown and system models are presented and discussed. The construction details and test results for several ESIMs are presented. Experimental results show the ESIM solves the electrostatically induced rotor shaft voltage and bearing problem without degrading the electromagnetic performance of the motor.
A novel secreted endoglycosidase from Enterococcus faecalis with activity on human immunoglobulin G and ribonuclease B. Vol. 279 (2004) 22558-22570 (2004)

In this article, the word “human” was accidentally inserted in front of the terms “ribonuclease B” and “RNase B” in several places. Consequently, ribonuclease B and RNase B should replace human ribonuclease B and human RNase B, respectively, throughout the text. RNase B represents ribonuclease extracted from bovine pancreas purchased from Sigma, as described under “Experimental Procedures.”
Mode purification in a relativistic magnetron with diffraction output (2013)

Summary form only given. Previous MAGIC particle-in-cell simulations performed at the University of New Mexico illustrated a mechanism by which a Gaussian TE <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">11</sub> microwave radiation pattern could be generated by a compact relativistic A6 magnetron with diffraction output (axial extraction) [1]. It employed an upstream strap that locked in the π-mode, something new to relativistic magnetrons [2], and a mode converter affixed to the downstream end of the anode block that acted to disrupt the desired π-mode. During portions of the TE <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">11</sub> RF cycle in which the electric field was low, such as when the polarity reversed, it was found that the polarization underwent rotation. Several changes are introduced in simulations to correct this problem at the expense of power and efficiency. These simulation results will be presented.
Study of Resting Energy Expenditure and Weight Changes during Pregnancy (2017)

In the present study, we have followed 4 pregnant women during pregnancy. The participants measured their resting energy expenditure (REE), weight, and activity, and recorded caloric intake. REE was measured with a mobile indirect calorimeter, Breezing TM on a weekly basis, and used to determine total energy expenditure (TEE) and daily caloric intake needs. The measured REE profi les indicated individual patterns in metabolic rate changes across pregnancy that could not be predicted by any known REE equation. The study outcomes suggest that the use of a mobile indirect calorimeter in conjunction with weight and physical activity measures allowed for the accurate estimate of caloric needs for pregnant women. The actual caloric intake (Breezing TM ) was compared with the self-reported caloric intake and demonstrated to have non-signifi cant differences in three of the four cases, and a signifi cant difference in one of the four cases. In addition, the participants reported that knowledge gained from tracking health parameters positively affected weight gain during pregnancy and helped to gain within a healthy weight range. Furthermore, all the participants were able to fully recover their pre-pregnancy weight within the year following birth.
Chapter 22—Standardized Labeling and Packaging as a Device for Prevention of Medication Errors (1983)

Accurate identification of products has been a matter of great concern to both manufacturers and consumers, and has received much attention in the past few years. Clearly, there is an urgent need for the development of standards by which manufacturers can best communicate important information concerning products to consumers, so that users can effectively comprehend all essential information and instructions provided by the manufacturers. Failing this, confusion and mishaps, some of which could be catastrophic but preventable, will result. Therefore, the importance of proper labeling and packaging cannot be overemphasized.
Toward robot-assisted stapes fenestration with a handheld micromanipulator (2012)

Stapedectomy is a delicate surgical procedure of the middle ear to improve hearing. In the middle ear there are anatomical structures that can be damaged during the surgery. Suppression of tremor during the procedure may reduce the likelihood of damage. This paper reports on a study of the feasibility of using Micron, a fully handheld micromanipulator, in stapedectomy. An ergonomic handle, a special tip, and a brace attachment were designed for this purpose and tested in a perforation task through a fixed speculum. Fenestration area and time in forbidden zones were analyzed in a penetration task under two conditions: unaided, and aided by tremor compensation. Preliminary results show a statistically significant improvement in cross-sectional area of fenestration and in time spent in forbidden zones.
Submillisecond response variable optical attenuator based on sheared polymer network liquid crystal (2004)

We demonstrate a variable optical attenuator (VOA) at lambda=1.55 microm using a sheared polymer network liquid crystal (SPNLC). The SPNLC exhibits a fast response time and weak wavelength dependency. Comparing with other polymer-stabilized liquid crystals, the SPNLC has lower driving voltage and negligible light scattering loss when the wavelength exceeds 700 nm. A reflection type VOA with ~0.24 ms response time and -32 dB dynamic range is demonstrated at room temperature and 35 Vrms voltage.
Molecular analysis of acute intermittent porphyria in a Finnish family with normal erythrocyte porphobilinogen deaminase (1989)

Porphobilinogen deaminase, the third enzyme of the haem biosynthetic pathway, is encoded by two distinct mRNA species expressed in a tissue-specific manner from a single gene. These two mRNAs are transcribed from two promoters and only differ in their first exon. An inherited deficiency or porphobilinogen deaminase in man is responsible for the autosomal dominant disease acute intermittent porphyria. Different classes of mutations have been described at the protein level suggesting that this is a heterogeneous disease. In the present report, we describe the molecular abnormality responsible for a variant form of acute intermittent porphyria where the enzyme defect is restricted to non-erythroid cells. Upon cloning and sequencing the mutant allele of a patient from a large Finnish kindred, a single-base substitution within the 5'-splice donor sequence of intron 1 was found at the last position of exon 1 (CG----CT). The identification of this mutation allowed us to detect asymptomatic gene carriers among family members using in vitro amplification of DNA and hybridization of the target sequence to allele-specific oligonucleotides.
Recursive Least-Squares Lattice Adaptive Algorithm Suitable for Fixed-Point Implementation (2006)

This paper proposes a version of recursive least-squares lattice (RLSL) adaptive algorithm suitable for fixed-point implementation. It is based on a modified form of the cost function in order to obtain an asymptotically unbiased estimator of the mean-square error, reducing significantly the dynamic range of the algorithm's parameters. Moreover, in order to achieve an enhanced numerical accuracy an error-feedback mechanism is employed. These improvements lead to facilities for fixed-point implementations.
Robust ultrasound image analysis using learning (2010)

Robust and accurate analysis of clinical ultrasound data is a challenging task due to the complexity of scanned anatomy, noise, shadows, signal dropouts and quantity of the information to be processed. As a result, traditional image analysis relying on the explicit encoding of prior knowledge such as perceptual grouping, variational or generative approaches is usually not enough to capture the complex appearance of ultrasound data. We will discuss a new class of methods that build on recent advances in discriminative machine learning to achieve robust and efficient performance. Image analysis is formulated as a multi-scale learning problem through which object models of increasing complexity are progressively learned. We will demonstrate example applications in Cardiology and OB/GYN.
Cinnamyl Alcohol Oxidation Using Supported Bimetallic Au–Pd Nanoparticles: An Optimization of Metal Ratio and Investigation of the Deactivation Mechanism Under Autoxidation Conditions (2020)

Abstract The aerobic oxidation of cinnamyl alcohol in toluene under autoxidation conditions has been studied using a range of 1 wt% Au–Pd/TiO 2 catalysts. The catalysts have been studied to determine the effect of preparation method (impregnation and sol immobilisation) and metal ratio on the conversion of cinnamyl alcohol and the selectivity to cinnamaldehyde. The catalysts prepared by sol-immobilisation demonstrate higher selectivity to the desired aldehyde than the analogous impregnation materials. The most active catalyst was found to be 0.75 wt% Au–0.25 wt% Pd/TiO 2 prepared by sol-immobilisation and this demonstrates the importance of metal ratio optimisation in this catalytic process. Furthermore, this metal ratio was found to be most stable under the reactions conditions with little change observed over multiple uses.
Failure of B6deficiency to affect performance of aging rats in a passive avoidance task (1980)

Male Fischer-344 rats from three age groups (6-7, 15-16, and 27-29 months) were given either a pyridoxine deficient diet or control diet for five weeks. Differences in body weight produced by the diets were evident in the youngest age groups but not in the oldest group in which all animals tended to lose weight. There was no evidence that diet or age affected performance during passive avoidance learning.
Real-time detection, tracking and occlusion reasoning (2023)

A system for object detection and tracking includes technologies to, among other things, detect and track moving objects, such as pedestrians and/or vehicles, in a real-world environment, handle static and dynamic occlusions, and continue tracking moving objects across the fields of view of multiple different cameras.
Background music reactive games (2010)

In this paper, we discuss the concept of games that react to their background music. Instead of limiting the player to a fixed set of songs, the background music can be any song chosen from the player's own music collection. Due to the relative simplicity of such existing game titles, we wanted to explore the potential of the concept more broadly in both digital audio and MIDI domains. Mappings between several musical and game parameters were studied by modifying two open-source games to react to their background music. The feedback collected with the game prototypes suggests that players appreciate the concept and find it entertaining. Based on the feedback and our experiments with different mappings, we present a set of design considerations for background music reactive games. The concept can be used to bring new life to existing games, and even a trivial game can be made interesting if the player can affect the game by changing the background music to his or her favorite song.
Rate enhancement of 1,3-dipolar cycloaddition ofN-methylindole: the singular role of Grignard reagents (1998)

The reactions of 2-N-methylindolyl and 2- and 3-benzo[b]thiophenyl anions with nitrile oxides and nitrilimines were performed in order to investigate whether the use of anionic dipolarophiles modifies a classical 1,3-dipolar cycloaddition. When lithium compounds were used as bases, the heterocyclic anions invariably acted as nucleophilic species; in contrast, when a Grignard reagent was employed, the N-methylindole gave cycloaddition products with an extraordinary rate enhancement. The hypothesis that N-methylindole and ethylmagnesium bromide give an adduct much more reactive than N-methylindole itself was supported by the results of a theoretical investigation. The structure and electron distribution of the adduct were determined by ab initio calculations and compared with those of known Grignard complexes with nitrogen ligands. The performance of different basis sets was tested. The quantum theory of atoms in molecules was used to determine atomic charges and to describe the nature of bonds in terms of the properties of the electron density at the bond critical points. © 1998 John Wiley & Sons, Ltd.
Supplementary Data Figures from A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer (2023)

&lt;p&gt;Supplementary Figures S1 - S7. Figure S1, Development and validation of a CRC-focused Nanostring panel and CMS classifier. Figure S2, Comparison of CRC Nanostring- and whole transcriptome-based classification of FFPE samples. Figure S3, Survival after relapse in non-metastatic patient cohorts. Figures S4, Genes significantly differentially expressed between the CMS groups are highly overlapping in both primary CRCs and metastases. Figure S5, Single nucleotide variants in matched sample pairs. Figure S6, Characterization of the procured cohort of matched primary and met samples. Figure S7, Characterization of orthotopically and HTV implanted CRC cell lines.&lt;/p&gt;
Method for calculating the effects of a dynamic entity interacting with poly(dT-dA)⋅poly(dT-dA): A dynamic enhancer-repressor action (1991)

The Green-function technique is used to study the interbase H-bond stretch poly(dT-dA)\ensuremath{\cdot}poly(dT-dA) (where dT is deoxythymine and dA is deoxyadenine) when an effective enzyme is attached to the helix. Four different one-hydrogen-bond attachment points are studied, and two different two-atom attachment points are studied. The enzyme attachments are allowed to oscillate at an unassumed resonant frequency associated with a thermally activated enzyme. This is equivalent in the Green-function formalism to a physical simulation of a simple enzyme attachment to a large DNA helix. The frequency dependence of hydrogen-bond thermal mean motion seems to be a key to the distinction between a dynamic repressor and enhancer action. The response is enhanced interbase hydrogen-bond-stretch amplitude when the effective enzyme attachment to the helix in poly(dT-dA)\ensuremath{\cdot}poly(dT-dA) is oscillating at frequencies that are near the interbase breathing mode of the helix. When the effective enzyme attachment is oscillating at frequencies far removed from the breathing mode of the helix, the response is usually repressed interbase hydrogen-bond stretch. Spectral density therefore may be a signature of protein enhancer or repressor action. A two-attachment effective enzyme is simulated, and it is shown that it can be approximated by the two individual one-point attachments if the force constant attaching them is small.
FingerPing (2018)

FingerPing is a novel sensing technique that can recognize various fine-grained hand poses by analyzing acoustic resonance features. A surface-transducer mounted on a thumb ring injects acoustic chirps (20Hz to 6,000Hz) to the body. Four receivers distributed on the wrist and thumb collect the chirps. Different hand poses of the hand create distinct paths for the acoustic chirps to travel, creating unique frequency responses at the four receivers. We demonstrate how FingerPing can differentiate up to 22 hand poses, including the thumb touching each of the 12 phalanges on the hand as well as 10 American sign language poses. A user study with 16 participants showed that our system can recognize these two sets of poses with an accuracy of 93.77% and 95.64%, respectively. We discuss the opportunities and remaining challenges for the widespread use of this input technique.
Noise-predictive partial-response equalizers and applications (2003)

The authors consider enhancing the performance of the traditional linear partial-response (PR) equalizer by using noise prediction techniques. The resulting noise-predictive PR equalizer consists of a forward linear PR equalizer followed by a linear predictor to whiten the noise and the residual distortion at the equalizer output. Assuming correct decisions and applying results from prediction theory, it is shown that the minimum mean-square error of a noise-predictive PR equalizer equals that of a decision-feedback equalizer which employs no PR shaping. This result shows that the performance of a receiver with a PR shaping equalizer can always be improved by attaching a noise-whitening predictor. Simulation results are presented for channels typically encountered in wire transmission and magnetic recording, i.e., channels with a spectral null at DC and strong high-frequency attenuation. The results show a substantial performance improvement when a noise-predictive PR equalizer is used.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Magnesium chloride tetrahydrate, MgCl2·4H2O (2011)

The title compound, MgCl(2)·4H(2)O, was crystallized at 403 K and its structure determined at 200 K. The structure is built up from MgCl(2)(H(2)O)(4) octahedra with a trans configuration. Each complex is situated on a crystallographic twofold axis, with the rotation axis aligned along one H(2)O-Mg-OH(2) axis. They are connected by a complex network of O-H···Cl hydrogen bonds. The structure contains two-dimensional sections that are essentially identical to those in the reported tetrahydrates of CrCl(2), FeCl(2), FeBr(2) and CoBr(2), but they are stacked in a different manner in MgCl(2)·4H(2)O compared with the transition metal structures.
Predicting Acute Kidney Injury in Intensive Care Unit Patients: The Role of Tissue Inhibitor of Metalloproteinases-2 and Insulin-Like Growth Factor-Binding Protein-7 Biomarkers (2018)

(TIMP-2*IGFBP7) at ICU admission has a good performance in predicting AKI, especially in the first 4 days in ICU.
Molecular basis of phenotype expression in homocystinuria (1994)

Cystathionine beta-synthase (CBS) deficiency is the most common cause of homocystinuria in humans. The human gene maps to chromosome 21q22.3 and encodes the CBS subunit of 551 amino acid residues (63kDa). CBS, a tetramer of these subunits, binds its two substrates, homocysteine and serine, and three additional ligands: pyridoxal 5'-phosphate, S-adenosylmethionine, and haem. Screening for mutations by expressing patient cDNA segments in E. coli permitted us to separate the parental CBS alleles, localize each mutation within one third of the cDNA, and functionally analyse the mutant protein. Using this method we identified the first 14 mutations in homocystinuria. The most common mutation in patients of predominantly 'Celtic' origin is the G919A transition which substitutes serine for glycine 307.
Comparison of spatial and ensemble averaging methods applied to wave propagation in finely layered media (1990)

PreviousNext No AccessSEG Technical Program Expanded Abstracts 1990Comparison of spatial and ensemble averaging methods applied to wave propagation in finely layered mediaAuthors: Fred E. StankeRobert BurridgeFred E. StankeSchlumberger‐Doll Research and Robert BurridgeSchlumberger‐Doll Researchhttps://doi.org/10.1190/1.1889908 SectionsAboutPDF/ePub ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinked InRedditEmail Permalink: https://doi.org/10.1190/1.1889908FiguresReferencesRelatedDetailsCited ByWave propagation with tunneling in a highly discontinuous layered mediumWave Motion, Vol. 13, No. 4 SEG Technical Program Expanded Abstracts 1990ISSN (print):1052-3812 ISSN (online):1949-4645Copyright: 1990 Pages: 1779 publication data© 1990 Copyright © 1990 Society of Exploration GeophysicistsPublisher:Society of Exploration Geophysicists HistoryPublished: 10 Feb 2005 CITATION INFORMATION Fred E. Stanke and Robert Burridge, (1990), "Comparison of spatial and ensemble averaging methods applied to wave propagation in finely layered media," SEG Technical Program Expanded Abstracts : 1062-1065. https://doi.org/10.1190/1.1889908 Plain-Language Summary PDF DownloadLoading ...
Preparation and characterization of cosmeceutical liposomes loaded with avobenzone and arbutin. (2013)

The objective of this study was to develop and characterize a liposome delivery system coencapsulating two cosmeceutical ingredients, avobenzone (AVO) and arbutin (AR). Two different liposome preparation methods, that is, thin film hydration and reverse-phase evaporation, were evaluated. To obtain the optimal formulation, various ratios of lipid to AVO or AR were tested. The effects of liposome formulation and preparation method on particle size, entrapment efficiency (EE), and skin permeation rate were studied. The mean particle size of the liposome formulations obtained by the thin film hydration method was smaller than that obtained by the reverse-phase evaporation method. The EE of AR and AVO in liposomes prepared by the thin film method, however, was lower than that prepared by the reverse-phase evaporation method. No differences in membrane permeation were observed between the two preparation methods. A large portion of AR permeated through the membrane into the receptor chamber. On the other hand, AVO remained in the donor chamber or accumulated in the membrane. The results of this study revealed that liposomes are a promising delivery system for coencapsulated AR and AVO. Liposomes may aid in retaining the sunscreen (AVO) at the surface of the skin for sun protection meanwhile facilitating the penetration of the whitening agent (AR) into the deeper layers of the skin for whitening effect.
SLFN5 Regulates LAT1-Mediated mTOR Activation in Castration-Resistant Prostate Cancer (2021)

Androgen deprivation therapy (ADT) is the standard of care for treatment of nonresectable prostate cancer. Despite high treatment efficiency, most patients ultimately develop lethal castration-resistant prostate cancer (CRPC). In this study, we performed a comparative proteomic analysis of three <i>in vivo</i>, androgen receptor (AR)-responsive orthograft models of matched hormone-naïve prostate cancer and CRPC. Differential proteomic analysis revealed that distinct molecular mechanisms, including amino acid (AA) and fatty acid metabolism, are involved in the response to ADT in the different models. Despite this heterogeneity, Schlafen family member 5 (SLFN5) was identified as an AR-regulated protein in CRPC. SLFN5 expression was high in CRPC tumors and correlated with poor patient outcome. <i>In vivo, SLFN5</i> depletion strongly impaired tumor growth in castrated conditions. Mechanistically, SLFN5 interacted with ATF4 and regulated the expression of LAT1, an essential AA transporter. Consequently, <i>SLFN5</i> depletion in CRPC cells decreased intracellular levels of essential AA and impaired mTORC1 signaling in a LAT1-dependent manner. These results confirm that these orthograft models recapitulate the high degree of heterogeneity observed in patients with CRPC and further highlight SLFN5 as a clinically relevant target for CRPC. SIGNIFICANCE: This study identifies SLFN5 as a novel regulator of the LAT1 amino acid transporter and an essential contributor to mTORC1 activity in castration-resistant prostate cancer.