gebhart/patrepeval huggingface dataset:
The Convergence of Technologies and Standards Across the Electronic Products Manufacturing Industry (SEMI, OSAT, and PCBA) to Realize Smart Manufacturing (2020)

The Vertical Segments of the Electronic Products Manufacturing Industry (Semiconductor, Outsourced System Assembly, and Test, and Printed Circuit Board Assembly) are converging and service offerings are consolidating due to advanced technology adoption and market dynamics. The convergence will cause shifts in the flow of materials across the supply chain as well as the introduction of equipment and processes across the segments. The ability to develop Smart Manufacturing and Industry 4.0 enabling technologies (e.g., big data analytics, artificial intelligence, cloud/edge computing, robotics, automation, IoT) that can be deployed within and between the Vertical Segments is critical. A Smart Manufacturing Technology Working Group (TWG) was formed by International Electronics Manufacturing Initiative (iNEMI) that included thought leaders from across the electronic products manufacturing industry. The TWG published a roadmap that included the situation analysis, critical gaps and key needs to realize Smart Manufacturing.
Spared comprehension of emotional prosody in a patient with global aphasia. (1999)

These observations further support the idea that verbal and emotional communication systems are independent and mediated by different hemispheres.
Correlations of the High Resolution MRI aspect of GH-secreting pituitary adenomas prior to treatment (2013)

peer reviewed
Emergency Tourniquets (2006)

Walters, Thomas J. PhD; Holcomb, John B. MD; Cancio, Lee C. MD; Beekley, Alec C. MD; Baer, David G. PhD Author Information
Workfunction (WF) Simulations of Ta/HfO2, Ta2C/HfO2 and Ta2C/La2O3/HfO2 Capped High-k Stacks (2007)

The electronic properties of tantalum based metal gates in contact with HfO2 are investigated through first-principles calculations. The (110) Ta surface has a p-type work function and is most likely to be formed at the interface with the dielectric. The influence of the transistor processing conditions is modeled by incorporating oxygen atoms in between the metal and the dielectric. Oxidizing the metal gate leads to an increase of the metal work function. To acquire either pMOS or nMOS work function values, the effective work function of the Ta (110)/HfO2 stack can be tuned by incorporating carbon or by inserting dielectric capping layers. The alloy of tantalum with carbon atoms reduces the metal work function which is also reported experimentally. Sandwiching a La2O3 capping layer between the gate and the dielectric leads to a work function reduction. These work function shifts are interpreted on the basis of the electronic density distribution at the interfacial region.
Designing Tabletop Groupware (2005)

Interactive tables are an emerging class of devices that are subject to different design constraints than other types of single display groupware. Through prototype-building and evaluation, we have identified three key design challenges for tabletop groupware: integrating access to public and private information, managing display elements, and mediating group dynamics. We discuss each of these issues and present approaches we have developed to address the challenges they present. ACM Classification: H5.3 [Information interfaces and presentation]: Group and Organization Interfaces computer-supported cooperative work. General terms: Design, Human Factors, Experimentation
Image-Based Alignment of 3D Scans (2021)

Full 3D scanning can efficiently be obtained using structured light scanning combined with a rotation stage. In this setting it is, however, necessary to reposition the object and scan it in different poses in order to cover the entire object. In this case, correspondence between the scans is lost, since the object was moved. In this paper, we propose a fully automatic method for aligning the scans of an object in two different poses. This is done by matching 2D features between images from two poses and utilizing correspondence between the images and the scanned point clouds. To demonstrate the approach, we present the results of scanning three dissimilar objects.
Big data for networking [Guest Editorial] (2016)

Big data analytics has shown great potential in optimizing operations, making decisions, spotting business trends, preventing threats, and capitalizing on new sources of revenues in various fields such as manufacturing, healthcare, finance, insurance, and retail. The management of various networks has become inefficient and difficult because of their high complexities and interdependencies. Big data, in forms of device logs, software logs, media content, and sensed data, provide rich information and facilitate a fundamentally different and novel approach to explore, design, and develop reliable and scalable networks. This Special Issue covers the most recent research results that address challenges of big data for networking. We received 45 submissions, and ultimately nine high quality papers, organized into two groups, have been selected for inclusion in this Special Issue.
Nonneurotoxic tetralin and indan analogs of 3,4-(methylenedioxy)amphetamine (MDA) (1990)

Four cyclic analogues of the psychoactive phenethylamine derivative 3,4-(methylenedioxy)amphetamine were studied. These congeners, 5,6- and 4,5-(methylenedioxy)-2-aminoindan (3a and 4a, respectively), and 6,7- and 5,6-(methylenedioxy)-2-aminotetralin (3b and 4b, respectively) were tested for stimulus generalization in the two-lever drug-discrimination paradigm. Two groups of rats were trained to discriminate either LSD tartrate (0.08 mg/kg) from saline, or (+/-)-MDMA.HCl (1.75 mg/kg) from saline. In addition, a 2-aminoindan (5a) and 2-aminotetralin (5b) congener of the hallucinogenic amphetamine 1-(2,5-dimethoxy-4- methylphenyl)-2-aminopropane (DOM) were also evaluated. None of the methylenedioxy compounds substituted in LSD-trained rats, while both 3a and 3b fully substituted in MDMA-trained rats. Compounds 4a and 4b did not substitute in MDMA-trained rats. Compounds 5a and 5b did not substitute in MDMA-trained rats, although 5a substituted in LSD-trained rats, but with relatively low potency compared to its open-chain counterpart. In view of the now well-established serotonin neurotoxicity of 3,4-(methylenedioxy)amphetamine and its N-methyl homologue 1, 3a and 3b were evaluated and compared to 1 for similar toxic effects following a single acute dose of 40 mg/kg sc. Sacrifice at 1 week showed that neither 3a nor 3b depressed rat cortical or hippocampal 5-HT or 5-HIAA levels nor were the number of binding sites (Bmax) depressed for [3H]paroxetine. By contrast, and in agreement with other reports, 1 significantly depressed all three indices of neurotoxicity. These results indicate that 3a and 3b have acute behavioral pharmacology similar to 1 but that they lack similar serotonin neurotoxicity.
Benzoxazolamines and Benzothiazolamines: Potent, Enantioselective Inhibitors of Leukotriene Biosynthesis with a Novel Mechanism of Action (1994)

A series of benzoxazolamine and benzothiazolamine analogs that inhibit leukotriene (LT) biosynthesis are described. The initial lead, (S)-N-(benzothiazol-2- yl)phenylalanine ethyl ester (5a), was discovered in a screening program for inhibition of Ca-ionophore-A23187-induced LTB4 release in human polymorphonuclear leukocytes (IC50 0.23 microM). Through structural modification, it was determined that hydrophobic substituents in the 5-position and replacement of the phenyl ring of phenylalanine with a cyclohexyl group greatly enhance potency. Several ester bioisosteres that retain potency and enantiomeric selectivity are described. Lead optimization culminated in (S)-N-[2-cyclohexyl-1-(2-pyridinyl)ethyl]-5-methyl-2-benzoxazolamine+ ++ (43b), IC50 0.001 microM. The compounds described are not inhibitors of 5-lipoxygenase but, rather, act at the level of arachidonic acid release.
Stochastic Demand Side Management in European Zonal Price Market (2019)

In this paper, demand-side management (DSM) is performed through demand response aggregators (DRAs) in an uncertain environment within zonal price market framework. The proposed scheme aims to allow cross-border electricity trading and optimize interconnections usage as well as to obtain optimum DR volume from the perspective of the Market Coupling Operator (MCO). The market consists of several zonal price markets as Nominated Electricity Market Operators (NEMO) who run their day-ahead and balancing market internally and communicate the information to the MCO to provide the cooperation with other NEMOs. To this end, a stochastic two-stage model is formulated in which the total operation cost from MCO's viewpoint is minimized. Accordingly, the model aims to consider day-ahead decisions in the first stage and balancing decisions in the second stage. Furthermore, the intermittent nature of renewable sources generation is handled by scenario generation with Monte-Carlo Simulation (MCS) method. NEMOs are physically connected as radial network. Therefore, all relative network constraints are taken into account as a linear power flow for radial networks. The results of the implementation of the proposed model demonstrate the effectiveness of various DR biddings on hourly DR volume, hourly DR cost and power exchange between different NEMOS.
Yellow fluorescent protein phiYFPv (Phialidium): structure and structure-based mutagenesis (2013)

The yellow fluorescent protein phiYFPv (λem(max) ≃ 537 nm) with improved folding has been developed from the spectrally identical wild-type phiYFP found in the marine jellyfish Phialidium. The latter fluorescent protein is one of only two known cases of naturally occurring proteins that exhibit emission spectra in the yellow-orange range (535-555 nm). Here, the crystal structure of phiYFPv has been determined at 2.05 Å resolution. The `yellow' chromophore formed from the sequence triad Thr65-Tyr66-Gly67 adopts the bicyclic structure typical of fluorophores emitting in the green spectral range. It was demonstrated that perfect antiparallel π-stacking of chromophore Tyr66 and the proximal Tyr203, as well as Val205, facing the chromophore phenolic ring are chiefly responsible for the observed yellow emission of phiYFPv at 537 nm. Structure-based site-directed mutagenesis has been used to identify the key functional residues in the chromophore environment. The obtained results have been utilized to improve the properties of phiYFPv and its homologous monomeric biomarker tagYFP.
Critical thickness for the formation of misfit dislocations originating from prismatic slip in semipolar and nonpolar III-nitride heterostructures (2016)

We calculate the critical thickness for misfit dislocation (MD) formation in lattice mismatched semipolar and nonpolar III-nitride wurtzite semiconductor layers for the case of MDs originated from prismatic slip (PSMDs). It has been shown that there is a switch of stress relaxation modes from generation of basal slip originated MDs to PSMDs after the angle between c-axis in wurtzite crystal structure and the direction of semipolar growth reaches a particular value, e.g., ∼70° for Al0.13Ga0.87N/GaN (h0h̄1) semipolar heterostructures. This means that for some semipolar growth orientations of III-nitride heterostructures biaxial relaxation of misfit stress can be realized. The results of modeling are compared to experimental data on the onset of plastic relaxation in AlxGa1−xN/GaN heterostructures.
Measurement of ultralow supermirror birefringence by use of the polarimetric differential cavity ringdown technique (2000)

We demonstrate a novel technique for measuring ultralow linear birefringence of supermirrors (high-reflectivity dielectric mirror coatings). The polarimetric cavity ringdown technique is used in conjunction with the differential detection scheme with circular polarization to enhance the measurement sensitivity. The technique could, in principle, provide the convenience and reliability of linear detection signals and a reasonable tolerance to experimental imperfections. Phase retardation and orientation of each cavity mirror can be determined separately without the influence of the other mirror. The minimum detectable phase retardation achieved experimentally with this technique is ~6 x 10(-8) rad.
SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line (2012)

HDAC inhibitors (HDACis) represent a class of anticancer agents including suberoylanilide hydroxamic acid (SAHA, Vorinostat), which has shown a strong antitumor effect, both in vitro and in vivo. Induction of apoptotic genes is an important pathway of SAHA cytotoxic mechanism of action and it has been largely described that SAHA induces sensitization of cell death receptor-resistant breast cancer cells to apoptosis. In this study, we investigated the activation of some apoptotic genes which could be responsible for the in vivo antitumor potency of SAHA in a model of human breast cancer. We found that the apoptotic gene pattern induced by SAHA in the MDA-MB-231 cell line involves the upregulation of some molecules belonging to the TNF superfamily. In particular, we demonstrated that the upregulation of the CD137 receptor/ligand system correlates with a synergistic cytotoxic effect when MDA-MB-231 cells are treated with the combination of SAHA and soluble CD137 receptor. To our knowledge, this is the first study to indicate that this member of the TNF superfamily, CD137, is modulated by SAHA treatment in breast cancer cells, suggesting that the combination of SAHA with this TNF-related receptor could be a new therapeutic approach for the treatment of tumors.
Asymmetric hydrogenation of unfunctionalized trisubstituted olefins with a chiral titanocene catalyst (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAsymmetric hydrogenation of unfunctionalized trisubstituted olefins with a chiral titanocene catalystRichard D. Broene and Stephen L. BuchwaldCite this: J. Am. Chem. Soc. 1993, 115, 26, 12569–12570Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/ja00079a040https://doi.org/10.1021/ja00079a040research-articleACS PublicationsRequest reuse permissionsArticle Views1551Altmetric-Citations167LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Lack of Effect of 12-Week Treatment with Risankizumab on the Pharmacokinetics of Cytochrome P450 Probe Substrates in Patients with Moderate to Severe Chronic Plaque Psoriasis (2018)

ClinicalTrials.gov Identifier: NCT02772601.
Anticalculus effect of a triclosan mouthwash containing phytate: a double‐blind, randomized, three‐period crossover trial (2009)

Background and Objective: Dental calculus occurs as a consequence of supersaturation of saliva with respect to calcium phosphates. This mineralization of dental plaque can be delayed by the presence of crystallization inhibitors, such as pyrophosphate or bisphosphonates. Phytate inhibits brushite and hydroxyapatite crystallization and has the potential to prevent dental calculi formation. The aim of the present study was to examine the effects of phytate and zinc, administered in a mouthwash solution, to prevent the formation of dental calculus. Material and Methods: Healthy dental plaque‐forming volunteers ( n = 25) took part in a randomized, double‐blind, three‐period crossover clinical study to assess the efficacy of a phytate‐containing mouthwash in relation to control and placebo effects. Subjects rinsed their mouths for 1 min, twice each day, with 20 mL of the test solution, without ingestion. Mouthwash efficacy was assessed through quantification of the amounts of calcium, phosphorus and magnesium present in the residues obtained by dental cleaning, performed by a single trained examiner. Results: A good correlation was found among total calcium, magnesium and phosphorus in calcified dental plaque residues, indicating that any of these variables is adequate for evaluating the reduction of plaque crystallization as calcium phosphate. A statistically significant decrease in total calcium, magnesium and phosphorus was found in the phytate‐treatment period compared with control and placebo periods, demonstrating the efficacy of the proposed treatment in reducing dental calculus formation. Conclusion: The high efficacy of phytate in reducing dental calculus formation suggests that this substance may be an effective treatment for preventing the development of calculus deposits.
Torsional Vibrations of Quartz Crystal Beams (1996)

An exact solution of a partial differential equation including elastic compliance constant 56, with respect to stress function has been found for torsional modes of vibration of an arbitrary (singly, doubly, triply) rotated beam with a pair of parallel free edges. The solution is obtained by relaxing the condition that the edge planes are perpendicular to the main faces of the beam. That is, the edges are off perpendicular by the angle = arctan (Os 56=s 55). The exact solution can reduce the difference of the calculated and measured values for a thicknessto-width ratio which gives the first-order temperature coefficient = 0. Also, a comparatively large inclination of the edge cuts is required to reduce the unwanted complicated mode shapes to simple ones.
Multi-shaped beam: development status and update on lithography results (2011)

According to the ITRS [1] photo mask is a significant challenge for the 22nm technology node requirements and beyond. Mask making capability and cost escalation continue to be critical for future lithography progress. On the technological side mask specifications and complexity have increased more quickly than the half-pitch requirements on the wafer designated by the roadmap due to advanced optical proximity correction and double patterning demands. From the economical perspective mask costs have significantly increased each generation, in which mask writing represents a major portion. The availability of a multi-electron-beam lithography system for mask write application is considered a potential solution to overcome these challenges [2, 3]. In this paper an update of the development status of a full-package high-throughput multi electron-beam writer, called Multi Shaped Beam (MSB), will be presented. Lithography performance results, which are most relevant for mask writing applications, will be disclosed. The MSB technology is an evolutionary development of the matured single Variable Shaped Beam (VSB) technology. An arrangement of Multi Deflection Arrays (MDA) allows operation with multiple shaped beams of variable size, which can be deflected and controlled individually [4]. This evolutionary MSB approach is associated with a lower level of risk and a relatively short time to implementation compared to the known revolutionary concepts [3, 5, 6]. Lithography performance is demonstrated through exposed pattern. Further details of the substrate positioning platform performance will be disclosed. It will become apparent that the MSB operational mode enables lithography on the same and higher performance level compared to single VSB and that there are no specific additional lithography challenges existing beside those which have already been addressed [1].
A Framework for Evaluating Gradient Leakage Attacks in Federated Learning (2020)

Federated learning (FL) is an emerging distributed machine learning framework for collaborative model training with a network of clients (edge devices). FL offers default client privacy by allowing clients to keep their sensitive data on local devices and to only share local training parameter updates with the federated server. However, recent studies have shown that even sharing local parameter updates from a client to the federated server may be susceptible to gradient leakage attacks and intrude the client privacy regarding its training data. In this paper, we present a principled framework for evaluating and comparing different forms of client privacy leakage attacks. We first provide formal and experimental analysis to show how adversaries can reconstruct the private local training data by simply analyzing the shared parameter update from local training (e.g., local gradient or weight update vector). We then analyze how different hyperparameter configurations in federated learning and different settings of the attack algorithm may impact on both attack effectiveness and attack cost. Our framework also measures, evaluates, and analyzes the effectiveness of client privacy leakage attacks under different gradient compression ratios when using communication efficient FL protocols. Our experiments also include some preliminary mitigation strategies to highlight the importance of providing a systematic attack evaluation framework towards an in-depth understanding of the various forms of client privacy leakage threats in federated learning and developing theoretical foundations for attack mitigation.
P‐79: Achieving High Contrast Ratio in IPS TFT‐LCDs by Domain Formation Control around Spacers (2000)

Abstract Reducing the light‐leakage caused by domain formation around spacers in IPS (in‐plane switching) TFT‐LCDs is investigated. It is found that the light‐leakage depends on the spacer material and surface alignment of the liquid crystal molecules on the spacers. High contrast ratio of over 200 is demonstrated by aligning liquid crystal molecules parallel to the spacer surface.
Comment on mr-2021-33 (2021)

<strong class="journal-contentHeaderColor">Abstract.</strong> The availability of a benchtop nuclear magnetic resonance (NMR) spectrometer, of low cost and easily transportable, can allow detection of low quantities of biosensors, provided that hyperpolarized species are used. Here we show that the micromolar threshold can easily be reached by employing laser-polarized xenon and cage molecules reversibly hosting it. Indirect detection of caged xenon is made via chemical exchange, using ultra-fast Z spectroscopy based on spatio-temporal encoding. On this non-dedicated low-field spectrometer, several ideas are proposed to improve the signal.
Flexible capacitive sensors for high resolution pressure measurement (2008)

Thin, flexible, robust capacitive pressure sensors have been the subject of research in many fields where axial strain sensing with high spatial resolution and pressure resolution is desirable for small loads, such as tactile robotics and biomechanics. Simple capacitive pressure sensors have been designed and implemented on flexible substrates in general agreement with performance predicted by an analytical model. Two designs are demonstrated for comparison. The first design uses standard flex circuit technology, and the second design uses photolithography techniques to fabricate capacitive sensors with higher spatial and higher pressure resolution. Sensor arrays of varying sensor size and spacing are tested with applied loads from 0 to 1 MPa. Pressure resolution and linearity of the sensors are significantly improved with the miniaturized, custom fabricated sensor array compared to standard flexible circuit technology.