gebhart/patrepeval huggingface dataset:
Factors Influencing Frontline Screening Nurses’ Depression as a Long-Term Impact of COVID-19 (2023)

Frontline screening nurses experienced exhaustion and depressive symptoms as a long-term impact of COVID-19. This study aimed to explore fatigue, depression, and empowerment among frontline screening nurses and examine the factors influencing depression. This was a descriptive cross-sectional study. The study included 140 frontline screening nurses in South Korea recruited from February to March 2021. The measures included a fatigue scale, the Text of Items Measuring Empowerment (TIME), and the Center for Epidemiological Studies Depression Scale (CES-D). The STROBE checklist was used for reporting aspects of the cross-sectional design. Frontline screening nurses showed high fatigue scores (<i>M</i> = 3.47, <i>SD</i> = 0.55), and 55.7% (<i>n</i> = 78) of them were depressed and had low empowerment scores (<i>M</i> = 3.53, <i>SD</i> = 0.69). Empowerment and fatigue were predictors of depression. Increased empowerment and decreased fatigue were important in decreasing depression. Therefore, efforts to provide sufficient staffing, screening for depression, and listening to nurses' voices are necessary.
Effect of Carbon Source as Additives in LiFePO[sub 4] as Positive Electrode for Lithium-Ion Batteries (2005)

The electrochemical properties of cathodes with different carbon contents were studied to determine the role of carbon as conductive additive. cathodes containing from 0 to 12% of conductive additive (carbon black or mixture of carbon black and graphite) were cycled at different C rates. The capacity of the cathode increased as conductive additive content increased. Carbon increased the utilization of active material and the electrical conductivity of electrode, but decreased volumetric capacity of electrode. This composition ( with 3 wt % of carbon and 3 wt % of Graphite) is suitable for HEV application.
Two-way all-optical AF relaying FSO systems over Malaga (M) channels with pointing errors (2016)

Two-way transmission protocol is an efficient method to overcome the spectral loss incurred due to half-duplex communication. In this paper, we propose to implement two-way transmission in an amplify-and-forward (AF) relaying free-space optical (FSO) system utilizing an AF relay with optical amplifier. The performance of the proposed FSO system using subcarrier intensity modulation (SIM) with intensity modulation/direct detection (IM/DD) over independent but not necessarily identically distributed (i.n.i.d) Malaga (M) atmospheric turbulence channels in presence of pointing errors is studied. Exact closed-form expressions for the moment generating function (MGF) and cumulative distribution function (CDF) of the end-to-end signal-to-noise ratio (SNR) are obtained in terms of extended generalized bivariate Meijer's G-functions (EGBMGF). Capitalizing on these new results, we derive exact closed-form expressions for various performance metrics of the considered FSO system including the outage probability, the average bit error rate (ABER), and the ergodic achievable-rate. All analytical results are thoroughly confirmed by Monte-Carlo (M-C) simulations.
A Novel Explorative Visualization Tool for Financial Time Series Data Analysis (2011)

Analyzing high dimensional time series data can be challenging, especially when the data consists of a large number of long time series. The task involves supporting interactive analysis of the data in both global and local fashion. In this paper we introduce a novel visual data analysis tool, which facilitates such type of tasks. The tool advances existing visualization techniques by integrating a pixel based visualization technique, which can display a large volume of data without overlaps, and line graph visualization, which provides an intuitive understanding of patterns and trends in the time series data.
The progress of electromagnetic wave leakage absorption film using SWCNT spray (2022)

CNT has a very light density of about half that of aluminum, but its strength is about 20 times that of steel, its current density resistance is more than 1000 times that of copper, and it also has higher thermal conductivity than copper. Although it is an excellent material that is expected to be used in various fields, its usage is special and it was difficult for everyone to handle it easily. We have succeeded in developing a flexible and stretchable CNT paint with the aim of applying this excellent material to DEA electrodes. This CNT paint can be easily applied to various materials by using a spray or other methods and since it can expand and contract, it can be applied to easily deformable materials such as polymers, wood, paper, and resin. It is possible to add the characteristics of CNT to various materials. One of the characteristics of CNTs that has been attracting attention in recent years is the radio wave absorption effect. In the later part of 2021, based on the results obtained from early that year, the shielding effect and absorption rate were measured and verified for the radio wave absorption effect in the millimeter wave bands. This research was conducted since the band is being increasingly used for systems like the automobile collision prevention radar system or 5G. In this experiment, we also conducted a demonstration experiment using an in-vehicle millimeter-wave radar system for the purpose of verifying its practicality. The purpose of this experiment was to prevent the target from being detected by applying SWCNT paint using the evaluation radar system used in the development of the in-vehicle millimeter-wave radar system.
Diagnostic Value of 1microgram Rapid ACTH Stimulation Test According to the Timing of Sampling of Serum Cortisol in Patients with Suspected Central Adrenal Insufficiency. (2004)

Background: Traditional testing of the hypothalamic-pituitary-adrenal axis function has essentially relied upon the insulin tolerance test or the metyrapone test (both tests are not only uncomfortable, but are also dangerous). The standard ACTH stimulation test uses an extremely supra-physiologic amount (250 ) of ACTH to evaluate a physiological response, which may result in a false normal response. The 1 rapid ACTH stimulation test is more physiological and more sensitive than the standard test, but there exist much controversy about when the serum cortisol should be measured or what the most appropriate cut-off point is for normality or whether the 1 ACTH commercial solution is needed. The aims of this study were to investigate 1) whether 1 of ACTH is an appropriate amount to stimulate the adrenal gland of patients that have suspected central adrenal insufficiency compared with insulin tolerance test (ITT) and 2) the diagnostic value of the 1 rapid ACTH stimulation test according to timing of sampling of serum cortisol. Methods: In order to evaluate the dose-response relationship between ACTH and cortisol, we performed the ITT in 77 patients with suspected central adrenal insufficiency with serial measurements of serum cortisol and plasma ACTH. We drew the blood samples in 10 min intervals between 10 and 60 min after the administration of 1 ACTH in 39 patients with central adrenal insufficiency and in 38 pituitary control patients with pituitary. ITT was used to confirm the diseases for the patients of central adrenal insufficiency, but for pituitary control patients, the ITT indicated normality in the patients. Also, all subjects underwent the 250 rapid ACTH stimulation test, and we compared the diagnostic value of the 1 ACTH stimulation test with the 250 test. Results: 1) The plasma ACTH level after the 1 ACTH stimulation test, even if it was be assumed as approximately 300 pg/mL, was expected to be sufficient enough to stimulate the adrenal cortex normally (serum cortisol levels >18 /dL) compared to the plasma ACTH level in the ITT. 2) The sensitivity and specificity of the 1 rapid ACTH stimulation test was highest with 92.3% and 84.2%, respectively, when serum cortisol levels were measured at 20, 30, and 40 min after the ACTH injection. The 1 rapid ACTH stimulation test was more sensitive than the 250 ACTH test (sensitivity: 92.3%, specificity: 71.8%). Conclusion: The 1 rapid ACTH stimulation test was more sensitive test in patients with suspected central adrenal insufficiency, and blood samples for cortisol levels should be drawn at 20, 30, and 40 min after ACTH administration.
Disruption of p16 and Activation of Kras in Pancreas Increase Ductal Adenocarcinoma Formation and Metastasis in vivo (2011)

Inactivation of tumor suppressor gene p16/INK4A and oncogenic activation of KRAS occur in almost all pancreatic cancers. To better understand the roles of p16 in pancreatic tumorigenesis, we created a conditional p16 knockout mouse line (p16flox/flox), in which p16 is specifically disrupted in a tissue-specific manner without affecting p19/ARF expression. p16flox/flox; LSL-KrasG12D; Pdx1-Cre mice developed the full spectrum of pancreatic intraepithelial neoplasia (mPanIN) lesions, pancreatic ductal adenocarcinoma (PDA), and metastases were observed in all the mice. Here we report a mouse model that simulates human pancreatic tumorigenesis at both genetic and histologic levels and is ideal for studies of metastasis. During the progression from primary tumors to metastases, the wild-type allele of Kras was progressively lost (loss of heterozygosity at Kras or LOH at Kras) in p16flox/flox; LSL- KrasG12D; Pdx1-Cre mice. These observations suggest a role for Kras beyond tumor initiation. In vitro assays performed with cancer cell lines derived from primary pancreatic tumors of these mice showed that cancer cells with LOH at Kras exhibited more aggressive phenotypes than those retained the wild-type Kras allele, indicating that LOH at Kras can provide cancer cells functional growth advantages and promote metastasis. Increased LOH at KRAS was also observed in progression of human pancreatic primary tumors to metastases, again supporting a role for the KRAS gene in cancer metastasis. This finding has potential translational implications- future KRAS target therapies may need to consider targeting oncogenic KRAS specifically without inhibiting wild-type KRAS function.
Automated Chemical Synthesis of PNA and PNA-DNA Chimera on a Nucleic Acid Synthesizer (1997)

Abstract Automated chemical synthesis of PNA and PNA-DNA chimera on a DNA synthesizer using the monomethoxytrityl/acyl protecting group strategy is described.
An Experimental and Computational Evaluation of Two Dual-Intake-Valve Combustion Chambers (1990)

&lt;div class="htmlview paragraph"&gt;Multi-dimensional computations were made of spark-ignited premixed-charge combustion in two engines having pent-roof-shaped combustion chambers and two intake valves per cylinder, one with a central spark plug and the other with dual lateral spark plugs. The basic specifications for the two engines were the same except for differences in the number of spark plugs and exhaust valves. The effects of swirl and equivalence ratio on combustion, wall heat transfer, and nitric oxide emission characteristics were examined using a global combustion model that accounts for laminar-kinetics and turbulent-mixing effects. The initial conditions on both mean-flow and turbulence parameters at intake valve closing (IVC) were estimated in order to simulate engine operation either with both intake valves active or with one valve deactivated. The predictions were compared with experimentally derived pressure-time, heat loss, and nitric oxide emission data.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;The model, consistent with experimental data, indicates that the dual lateral ignition engine responds more favorably to valve deactivation as charge dilution is increased, and shows flame convection to be the source of the dual lateral ignition engine's superior dilute performance. The results also indicate that when the effects of flame convection are considered, the model predicted top dead center (TDC) turbulence intensities are in good agreement with experimentally derived apparent TDC turbulence intensities for both engines with and without valve deactivation.&lt;/div&gt;
α-MSH inhibits inflammatory signalling in Schwann cells (2004)

Peripheral nervous system injury may be corrected by surgical repair, but in many cases this is not possible and will result in loss of motor and sensory function. Schwann cells provide many neurotrophic signals essential for axon regeneration and immediately after injury inflammatory cytokines are released necessary for Schwann cell de-differentiation. However, extended periods of inflammation after injury prevent Schwann cell proliferation, and therefore interventional approaches to enhance proliferation may in turn improve axon regeneration. We therefore investigated the ability of alpha-melanocyte stimulating hormone (alpha-MSH; a potent anti-inflammatory peptide) to inhibit the activation of the NF-kappaB transcription factor (required for inflammatory signalling) in cultured rat primary Schwann cells, stimulated with tumour necrosis factor-alpha (TNF-alpha) or interferon-gamma (IFN-gamma). Both cytokines activated NF-kappaB rapidly after 60 min incubation, observed as a translocation from the cytoplasm to the nucleus. alpha-MSH inhibited activation (i.e. inhibited nuclear translocation) in response to TNF-alpha or IFN-gamma by 81% and 100% respectively. The anti-inflammatory properties of this peptide may therefore have potential for treatment of peripheral nerve injury to improve the healing response.
A NOVEL PLATFORM FOR IMAGE FUSED ELECTROMAGNETIC TRACKED PERCUTANEOUS RFA OF RENAL CELL CARCINOMA (2009)

You have accessJournal of Urology1 Apr 2009A NOVEL PLATFORM FOR IMAGE FUSED ELECTROMAGNETIC TRACKED PERCUTANEOUS RFA OF RENAL CELL CARCINOMA Benjamin B Storey, Gopal Gupta, Juan Proano, Dawud Lankford, Deborah R Kaye, Julie Locklin, Aaron Krill, Jochen Kruecker, Sheng Xu, Gennady Bratslavsky, Neil Glossop, Laura Glenn, Bradford Wood, Jeannie Menalo, and Peter A Pinto Benjamin B StoreyBenjamin B Storey More articles by this author , Gopal GuptaGopal Gupta More articles by this author , Juan ProanoJuan Proano More articles by this author , Dawud LankfordDawud Lankford More articles by this author , Deborah R KayeDeborah R Kaye More articles by this author , Julie LocklinJulie Locklin More articles by this author , Aaron KrillAaron Krill More articles by this author , Jochen KrueckerJochen Kruecker More articles by this author , Sheng XuSheng Xu More articles by this author , Gennady BratslavskyGennady Bratslavsky More articles by this author , Neil GlossopNeil Glossop More articles by this author , Laura GlennLaura Glenn More articles by this author , Bradford WoodBradford Wood More articles by this author , Jeannie MenaloJeannie Menalo More articles by this author , and Peter A PintoPeter A Pinto More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(09)60524-3AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "A NOVEL PLATFORM FOR IMAGE FUSED ELECTROMAGNETIC TRACKED PERCUTANEOUS RFA OF RENAL CELL CARCINOMA." The Journal of Urology, 181(4S), pp. 182–183 © 2009 by American Urological AssociationFiguresReferencesRelatedDetails Volume 181Issue 4SApril 2009Page: 182-183 Advertisement Copyright & Permissions© 2009 by American Urological AssociationMetricsAuthor Information Benjamin B Storey More articles by this author Gopal Gupta More articles by this author Juan Proano More articles by this author Dawud Lankford More articles by this author Deborah R Kaye More articles by this author Julie Locklin More articles by this author Aaron Krill More articles by this author Jochen Kruecker More articles by this author Sheng Xu More articles by this author Gennady Bratslavsky More articles by this author Neil Glossop More articles by this author Laura Glenn More articles by this author Bradford Wood More articles by this author Jeannie Menalo More articles by this author Peter A Pinto More articles by this author Expand All Advertisement PDF downloadLoading ...
Non-coding RNA/microRNA-modulatory dietary factors and natural products for improved cancer therapy and prevention: Alkaloids, organosulfur compounds, aliphatic carboxylic acids and water-soluble vitamins (2016)

Non-coding small RNA molecules, the microRNAs (miRNAs), contribute decisively to the epigenetic regulation processes in cancer cells. Problematic pathogenic properties of cancer cells and the response of cancers towards anticancer drugs are highly influenced by miRNAs. Both increased drug activity and formation of tumor resistance are regulated by miRNAs. Further to this, the survival and proliferation of cancer cells and the formation of metastases is based on the modulated expression of certain miRNAs. In particular, drug-resistant cancer stem-like cells (CSCs) depend on the presence and absence of specific miRNAs. Fortunately, several small molecule natural compounds were discovered that target miRNAs involved in the modulation of tumor aggressiveness and drug resistance. This review gives an overview of the effects of a selection of naturally occurring small molecules (alkaloids, organosulfur compounds, aliphatic carboxylic acids and water-soluble vitamins) on miRNAs that are closely tangled with cancer diseases.
NANOTECHNOLOGY-MEDIATED DELIVERY OF CHEMOTHERAPY IN THE TREATMENT OF UROTHELIAL CARCINOMA (2009)

You have accessJournal of Urology1 Apr 2009NANOTECHNOLOGY-MEDIATED DELIVERY OF CHEMOTHERAPY IN THE TREATMENT OF UROTHELIAL CARCINOMA Armine K Smith, William A Larchian, Amit R Patel, Shihua Jin, Eddie S y Chan, Anil A Thomas, John B Klein, Warren D Heston, and Vinod Labhasetwar Armine K SmithArmine K Smith More articles by this author , William A LarchianWilliam A Larchian More articles by this author , Amit R PatelAmit R Patel More articles by this author , Shihua JinShihua Jin More articles by this author , Eddie S y ChanEddie S y Chan More articles by this author , Anil A ThomasAnil A Thomas More articles by this author , John B KleinJohn B Klein More articles by this author , Warren D HestonWarren D Heston More articles by this author , and Vinod LabhasetwarVinod Labhasetwar More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(09)61161-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "NANOTECHNOLOGY-MEDIATED DELIVERY OF CHEMOTHERAPY IN THE TREATMENT OF UROTHELIAL CARCINOMA." The Journal of Urology, 181(4S), pp. 408–409 © 2009 by American Urological AssociationFiguresReferencesRelatedDetails Volume 181Issue 4SApril 2009Page: 408-409 Advertisement Copyright & Permissions© 2009 by American Urological AssociationMetricsAuthor Information Armine K Smith More articles by this author William A Larchian More articles by this author Amit R Patel More articles by this author Shihua Jin More articles by this author Eddie S y Chan More articles by this author Anil A Thomas More articles by this author John B Klein More articles by this author Warren D Heston More articles by this author Vinod Labhasetwar More articles by this author Expand All Advertisement PDF downloadLoading ...
NMR study of the molecular and electronic structure of the heme cavity of Aplysia metmyoglobin. Resonance assignments based on isotope labeling and proton nuclear Overhauser effect measurements (1986)

The 1H NMR characteristics of the high-spin metmyoglobin from the mollusc Aplysia limacina have been investigated and compared with those of the myoglobin (Mb) from sperm whale. Aplysia metMb exhibits a normal acid----alkaline transition with pK approximately 7.8. In the acidic form, the heme methyl and meso proton resonances have been assigned by 1H NMR using samples reconstituted with selectively deuterated hemins and in the latter case by 2H NMR as well. On the basis of the methyl peak intensities and shift pattern, heme rotational disorder could be established in Aplysia Mb; approximately 20% of the protein exhibits a reversed heme orientation compared to that found in single crystals. Three meso proton resonances have been detected in the upfield region between -16 and -35 ppm, showing that the chemical shift of such protons can serve as a diagnostic probe for a pentacoordinated active site in hemoproteins, as previously shown to be the case in model compounds. The temperature dependence of the chemical shift of the meso proton signals deviates strongly from the T-1 Curie behavior, reflecting the presence of a thermally accessible Kramers doublet with significant S = 3/2 character. Nuclear Overhauser effect, NOE, measurements on Aplysia metMb have provided the assignment of individual heme alpha-propionate resonances and were used to infer spatial proximity among heme side chains. The hyperfine shift values for assigned resonances, the NOE connectivities, and the NOE magnitudes were combined to reach a qualitative picture of the rotational mobility and the orientation of the vinyl and propionate side chains of Aplysia metMb relative to sperm whale MbH2O.(ABSTRACT TRUNCATED AT 250 WORDS)
Écotoxicologie et modélisation spatiale en dynamique de population : exemple d'une population de truites exposée à une pollution dans un réseau de rivières (2002)

Despite rapidly evolving technologies, an accurate and thorough clinical neurologic assessment is still crucial to understanding presenting symptoms and signs. It is the most exciting but also challenging part of the diagnostic puzzle, essential to establishing a rational working hypothesis and a consistent management plan. Flexibility, creativity, and social skills are needed to elicit the child's participation. History taking is of the utmost importance, requiring not only time and perseverance, but also knowledge and effective communication to obtain relevant and precise information. Understanding what is being tested and distinguishing the normal from the abnormal are indispensable in reaching a correct clinical interpretation. The clinician needs to tailor an individualized approach for each patient according to the chief complaint, clinical context, and the child's chronologic and developmental age. The questions about the nature, localization, and etiology must be addressed first and then summarized and developed into a reasonable diagnostic hypothesis and differential diagnosis. This chapter aims to guide the reader through a situation-related approach from history taking and neurologic examination to a systematic, step-by-step interpretation of the information and findings. It also provides some practical advice on how to avoid common pitfalls.
Car–Parrinello methods (1990)

Brief descriptions are given of the total-energy pseudopotential technique and of Car and Parrinello's molecular dynamics method for performing pseudopotential calculations. A review of the technical problems associated with performing total-energy pseudopotential calculations is presented. A number of alternative computational schemes for performing total-energy pseudopotential calculations are described and it is shown that all the technical problems associated with the total-energy pseudopotential method can be overcome by using a computational scheme based on conjugate gradient techniques.
[Ultrastructural localization of pituitary hormones by immunocytochemical reactions in ultrathin sections of adenomas]. (1985)

Human pituitary adenomas were fixed in glutaraldehyde and embedded in epon. Ultrathin sections were incubated either with anti-hGH, anti-hPRL or anti-hLH. They were incubated with second step goat anti-rabbit immunoglobulins linked to gold particles. Two PRL secreting adenomas, one GH and PRL secreting adenoma, one ACTH secreting adenoma and two non secreting adenomas were studied. The specificity and the limits of the method were discussed in relation with the results obtained in light microscopy with the PAP method.