gebhart/patrepeval huggingface dataset:
Experimental Demonstration of Adaptive-Optics-Based Turbulence Mitigation in a Mode-Multiplexed Free-Space Optical Link by Using both Radial and Azimuthal Spatial Indices (2022)

We experimentally demonstrate turbulence mitigation by adaptive optics for a 400-Gbit/s free-space link multiplexing four Laguerre Gaussian modes using both radial and azimuthal indices. The turbulence-induced power loss and crosstalk are reduced by ~10 dB and ~18 dB, respectively.
Reversal reaction to Hansen's disease. (2002)

A 25-year-old man with a history of mid-borderline (BB) Hansen's disease developing a reversal reaction after starting dapsone and rifampin therapy is presented. His clinical features included erythematous, edematous plaques and peripheral neuropathy. Reversal reactions are caused immunologically by enhanced cell-mediated (Th-1) immunity to Mycobacterium leprae, resulting in inflammation of infected tissues, such as skin and nerves. Acute neuritis can lead to permanent nerve damage and necessitate prompt treatment with prednisone and/or clofazamine.
Critical field enhancement of asymptotic optical bound states in the continuum (2015)

We study spectral singularities and critical field enhancement factors associated with embedded photonic bound states in subwavelength periodic Si films. Ultrahigh-Q resonances supporting field enhancement factor exceeding 10(8) are obtained in the spectral vicinity of exact embedded eigenvalues in spite of deep surface modulation and vertical asymmetry of the given structure. Treating relations between the partial resonance Q and field enhancement factors with an analytical coupled-mode model, we derive a general strategy to maximize the field enhancement associated with these photonic bound states in the presence of material dissipation. The analytical expression for the field enhancement quantitatively agrees with rigorous numerical calculations. Therefore, our results provide a general knowledge for designing practical resonance elements based on optical bound states in the continuum in various applications.
Identification, host range and infection process of Meloidogyne marylandi from turf grass in Israel (2003)

Abstract A population of a root-knot nematode species was isolated from Zoysia japonica in a turf nursery in Israel. Measurements and morphology of the second-stage juveniles and adult females, including perineal pattern, indicated this nematode to be Meloidogyne marylandi. In addition, esterase (Est) and malate dehydrogenase (Mdh) isozymes were studied for the first time for this species which is shown to be characterised by VS1 Est band and a N1c Mdh pattern. Host range tests showed that the turf grasses Stenotaphrum secundatum, Dactyloctenium australe and Paspalum vaginatum, corn (Zea mays) and oat (Avena sativa) were non-hosts or resistant. Kikuyu grass (Pennisetum clandestinum), wheat (Triticum aestivum), barley (Hordeum vulgare), bristle oat (Avena strigosa), Siberian millet (Echinochloa frumentaceae) and pearl millet (Pennisetum glaucum) were susceptible to the nematode. The second-stage juveniles of M. marylandi penetrated the elongation zone of wheat roots but did not reach the meristematic zone and settled with their anterior end toward the root tip. This contrasted with M. javanica or M. incognita which migrated to the meristematic zone, and turned around with their anterior toward the root base. Meloidogyne marylandi juveniles induced giant cells from vascular parenchyma cells and caused no or only small galls on the roots.
Dipeptidyl Peptidase-4 Inhibition by Vildagliptin and the Effect on Insulin Secretion and Action in Response to Meal Ingestion in Type 2 Diabetes (2008)

OBJECTIVE—The purpose of this study was to determine the mechanism by which dipeptidyl peptidase-4 inhibitors lower postprandial glucose concentrations. RESEARCH DESIGN AND METHODS—We measured insulin secretion and action as well as glucose effectiveness in 14 subjects with type 2 diabetes who received vildagliptin (50 mg b.i.d.) or placebo for 10 days in random order separated by a 3-week washout. On day 9 of each period, subjects ate a mixed meal. Insulin sensitivity (SI), glucose effectiveness, and β-cell responsivity indexes were estimated using the oral glucose and C-peptide minimal models. At 300 min 0.02 unit/kg insulin was administered intravenously. RESULTS—Vildagliptin reduced postprandial glucose concentrations (905 ± 94 vs. 1,008 ± 104 mmol/6 h, P = 0.02). Vildagliptin did not alter net SI (7.71 ± 1.28 vs. 6.41 ± 0.84 10−4 dl · kg−1 · min−1 · μU−1 · ml−1, P = 0.13) or glucose effectiveness (0.019 ± 0.002 vs. 0.018 ± 0.002 dl · kg−1 · min−1, P = 0.65). However, the net β-cell responsivity index was increased (35.7 ± 5.2 vs. 28.9 ± 5.2 10−9 min−1, P = 0.03) as was total disposition index (381 ± 48 vs. 261 ± 35 10−14 dl · kg−1 · min−2 · pmol−1 · l−1, P = 0.006). Vildagliptin lowered postprandial glucagon concentrations (27.0 ± 1.1 vs. 29.7 ± 1.5 μg · l−1 · 6 h−1, P = 0.03), especially after administration of exogenous insulin (81.5 ± 6.4 vs. 99.3 ± 5.6 ng/l, P = 0.02). CONCLUSIONS—Vildagliptin lowers postprandial glucose concentrations by stimulating insulin secretion and suppressing glucagon secretion but not by altered insulin action or glucose effectiveness. A novel observation is that vildagliptin alters α-cell responsiveness to insulin administration, but the significance of this action is as yet unclear.
Enhanced electromagnetic pressure in a sandwiched reflection grating (2012)

We suggest that strongly enhanced electromagnetic pressure can be induced at the boundary of a sandwiched reflection grating due to a special kind of deep subwavelength Fabry-Perot (FP)-like resonance. A theoretical formula will be derived and employed to study this effect at both the infrared and microwave regimes. The magnitude or sign of the electromagnetic force can be tuned by adjusting the system parameters, which in turn adjust the balance between the electric and magnetic energies stored in the system. In the infrared regime, a strong attractive pressure was found, which is controllable by the FP cavity length. In the microwave band, a repulsive pressure can be realized in most situations. What is rather amazing is that a strong attractive electromagnetic pressure, which has not been found previously, can also be demonstrated in some geometries in the microwave regime.
ChemInform Abstract: Cyclizations and Intermolecular Additions of Alkoxycarbonyloxy Radicals from N‐Hydroxypyridine‐2‐thione Carbonates. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
IRF4 mutations in chronic lymphocytic leukemia (2011)

Interferon regulatory factor 4 (IRF4) is a member of the interferon regulatory factor family of transcription factors and has been shown to have critical functions at several stages of B-cell development. Genome-wide association study identified a polymorphism in the 3' untranslated region of IRF4 as a chronic lymphocytic leukemia risk locus. In this study, we report a recurrent heterozygous somatic mutation in the DNA-binding domain of IRF4 detected in 7 of 457 chronic lymphocytic leukemia patients (1.5%). Patients with IRF4 mutation have a good prognosis, and 4 of 6 have a trisomy 12. We also found that IRF4 mRNA expression is higher in the patients with the mutation.
Capsule and melanin synthesis inCryptococcus neoformans (2001)

Melanization is a property that is shared among several human pathogenic fungi, whereas encapsulation is a property unique to Cryptococcus neoformans. Focusing on C. neoformans, the current knowledge of the structure and synthesis of the melanin and polysaccharide capsule is discussed. The importance of such basic biological information is underscored by the involvement of each to the pathogenic ability of the fungus and their potential as drug targets, yet areas where critical data remain elusive are clearly visible. Finally, in recognition of the fact that C. neoformans is a free-living organism, we conclude by examining the possible biological importance of each of these traits for environmental survival of the fungus.
New compounds: potential antituberculous agents. 2. N-Arylformamidino-N'-(dialkyl and diaryl substituted)thiosemicarbazones (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNew compounds: potential antituberculous agents. 2. N-Arylformamidino-N'-(dialkyl and diaryl substituted)thiosemicarbazonesPramod K. Srivastava, Jugmander S. Upadhyaya, and Rajesh D. SharmaCite this: J. Chem. Eng. Data 1976, 21, 3, 388–389Publication Date (Print):July 1, 1976Publication History Published online1 May 2002Published inissue 1 July 1976https://pubs.acs.org/doi/10.1021/je60070a024https://doi.org/10.1021/je60070a024research-articleACS PublicationsRequest reuse permissionsArticle Views39Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Experiments on fast cell search algorithm for intercellasynchronous W-CDMA mobile radio (1999)

Laboratory and field experiment results for a two-step cell search algorithm using scramble code masking for intercell asynchronous W-CDMA mobile radio are presented. The scramble code is masked at diferent time positions during each scramble period in the forward link common control channel (CCH) for scramble code timing detection at the mobile receiver. 16 scramble codes are used. The cell search time achievable with the authors&apos; recently proposed three-step cell search algorithm is estimated from the experimental results; cell search can be accomplished within ~960 ms at a probability of 93% in the case of 512 scramble codes and 16 scramble code groups.
Data from Frequent Nonrandom Activation of Germ-Line Genes in Human Cancer (2023)

&lt;div&gt;Abstract&lt;p&gt;The growing class of cancer/germ-line genes is characterized by a unique expression pattern with transcription restricted to germ cells and cancer cells. It is not known which fraction of germ-line genes is ectopically activated in tumor cells and whether this fraction displays common features as compared with strictly germ-line genes remaining silent in cancer. Using an unbiased genome-wide scanning approach, representative samples of both cancer/germ-line genes as well as strictly germ-line-specific genes were determined. Comparative analysis disclosed highly significant diametric characteristics for these two categories of genes with regard to sex specificity, developmental stage of physiological expression during gametogenesis, chromosomal localization, and epigenetic regulation of expression. Our findings provide class predictors for germ cell-specific gene activation in cancer. The identification of highly congruent expression patterns in cancer and in DNA methyltransferase-deficient cells suggests an underlying common epigenetic mechanism for activation of germ-line genes in cancer.&lt;/p&gt;&lt;/div&gt;
Radiation Ablation of Liver Metastases (1999)

Caring for oncology patients has taught physicians much about the strength of the human spirit. Hope bounds eternal for most patients. However, when a diagnosis of liver metastases is shared with patients, it comes as a universally crushing blow. Even those with AIDS-associated malignancies will inquire about their liver status with great trepidation. Further, patients with some of the most aggressive malignancies remain hopeful noting, "Well, at least it hasn't spread to my liver." This indicates that most members of the lay public recognize the grave prognosis of liver metastases.KeywordsLiver MetastasisHepatic ResectionHepatic MetastasisColorectal Liver MetastasisExtrahepatic DiseaseThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Side-wall oxide isolation self-aligned technique for SiGe/Si HBTs (2002)

A low temperature side-wall oxide isolation self-aligned technique for SiGe/Si HBTs has been developed, by which the SiGe/Si HBTs with advanced performances have been fabricated. Its current gain is about 70 at 300 K and is more than 2000 at 77 K. It also has superior saturation characteristics with Early voltage over 200 V. Moreover, using this technique, the transverse base resistance is reduced by 50%, resulting in the cutoff frequency and the maximum frequency of oscillation being increased considerably. N/sub F/ is reduced by 3 dB, compared with those devices fabricated by the conventional Si techniques.
Development of a Linear-Motor-Driven Table with Hydrostatic Water Bearings : Design and Development of the Table System and Its Static Characteristics(Machine Elements and Manufacturing) (2009)

A linear-motor-driven table sustained by constant-flow hydrostatic water bearings which are free from environmental pollution is developed. The static characteristic of the developed table system is experimentally investigated. Since the constant-flow hydrostatic bearings needs no restrictor, such as orifice or capillary tube, blocking of the restrictor by bacteria, sludge, and rust of steel can be avoided. A miniature gear pump applied showed good constant flow performance for the hydrostatic bearing without pump pulsation. A simple one-side-recess type bearing is chosen for the system. In order to obtain high sustaining stiffness, preload is given to the bearings using attractive force of a core-type linear motor. The preload is effective in both vertical and horizontal directions by using the slant arrangement of the linear-motor magnet. The measured sustaining force is 4.5kN and static stiffness is 0.66kN/μm under bearing clearance h=16μm and flow rate Q=0.92mL/s.
Hepatitis E Virus Induces Brain Injury Probably Associated With Mitochondrial Apoptosis (2019)

Hepatitis E virus (HEV) infection has been associated with extrahepatic manifestations, particularly neurological disorders. Although it has been reported that HEV infection induced hepatocyte apoptosis associated with mitochondria injury, activation of mitochondrial apoptotic pathway in the central nervous system during HEV infection was not clearly understood. In this study, the induction of mitochondrial apoptosis-associated proteins and pro-inflammatory cytokines were detected in HEV infected Mongolian gerbil model and primary human brain microvascular endothelial cells (HBMVECs). Mitochondrial exhibited fragments with loss of cristae and matrix in HEV infected brain tissue by transmission electron microscope (TEM). <i>In vitro</i> studies showed that expression of NADPH oxidase 4 (NOX4) was significantly increased in HEV infected HBMVECs (<i>p</i> < 0.05), while ATP5A1 was significantly decreased (<i>p</i> < 0.01). Expressions of pro-apoptotic proteins were further evaluated. Bax was significantly increased in both HEV infected brain tissues and HBMVECs (<i>p</i> < 0.01). <i>In vivo</i> studies showed that caspase-9 and caspase-3 were activated after HEV inoculation (<i>p</i> < 0.01), associated with PCNA overexpression as response to apoptosis. Cytokines were measured to evaluate tissue inflammatory levels. Results showed that the release of TNFα and IL-1β were significantly increased after HEV infection (<i>p</i> < 0.01), which might be attributed to microglia activation characterized by high level of IBA1 expression (<i>p</i> < 0.01). Taken together, these data support that HEV infection induces high levels of pro-inflammatory cytokines, associated with mitochondria-mediated apoptosis. The results provide new insight into mechanisms of extra-hepatic injury of HEV infection, especially in the central nervous system.
Anisomycin and verapamil influence the action of progesterone on regulation of term human myometrial contractile activity (1997)

The results indicate that the actions of progesterone on term myometrial contractile activity occur without protein synthesis and that increased Ca2+ influx or decreased outward transport of Ca2+ may play a possible role)
Practical and theoretical issues in prefetching and caching (1997)

Submitted inpartial ful llment of the requirements for the degree ofDoctor of Philosophy. Thesis Committee:
Angiostatic Effects of Aspirin in Hypoxia-Reoxygenation Are Linked to Modulation of TGFβ1 Signaling (2010)

Hypoxia-reoxygenation (HR) is a major driver for angiogenesis in atherosclerotic plaques and tumors. Angiogenesis is a multistep process requiring stimulation of proliferation and migration of endothelial cells in response to a number of growth factors, including transforming growth factor (TGFβ1). Aspirin (acetylsalicylic acid) has been shown to reduce atherosclerosis-related events as well as development of certain tumors. We examined the role of aspirin in HR-mediated angiogenesis from human umbilical vein endothelial cells (HUVECs). We found that aspirin (0.5 and 1 mmol/L) markedly (by about 30%, P < .01) reduced HR-mediated tube formation. Next, we studied changes in TGFβ1 and its type 1 receptor (TGFβ-R1) as well as in the transcription of p53 and p21 during HR-mediated angiogenesis. Hypoxia-reoxygenation modestly increased TGFβ1 and decreased its type 1 receptor (TGFβ-R1) transcription (both P-NS) and reduced the transcription of p53 and p21 (P < .05). Treatment of HUVECs with aspirin suppressed TGFβ1 and enhanced TGFβ-R1 mRNA expression during HR (both P < .05 vs HR alone) without a change in p53 and p21 (P-NS). In other experiments, treatment of cells with TGFβ1 antibody modestly decreased HR-mediated angiogenesis; however, TGFβ1 antibody treatment significantly enhanced the inhibitory effect of aspirin on tube formation. Based on these data, we suggest that the inhibitory effect of aspirin on HR-mediated angiogenesis involves TGFβ1-TGFβ-R1 pathway.
VEGF Improves, Whereas sFlt1 Inhibits, BMP2-Induced Bone Formation and Bone Healing Through Modulation of Angiogenesis (2005)

This study, along with previously published work, shows that VEGF interacts synergistically with both BMP4 and BMP2 but elicits substantially different effects with these two BMPs.
Multi-dimensional flow-adapted compressed sensing (MDFCS) for time-resolved velocity-encoded Phase Contrast MRA (2013)

4D time-resolved velocity-encoded Phase-Contrast MRI (t-v PC MRI) is a fully non-invasive technique to assess hemodynamics in-vivo and can thus be extremely helpful in diagnosis and treatment planning. A common drawback of 4D acquisitions with high spatial and temporal resolution is the long acquisition time, which still inhibits the wider clinical use of such exams. Since a certain degree of data redundancy or sparsity can be expected in temporal as well as in velocity encoding direction, the combination of recently proposed Compressed Sensing techniques with t-v PC MRI might be promising. In this work, a Multi-Dimensional Flow-Adapted compressed Sensing (MDFCS) method is presented, which aims at exploiting these properties by using a dedicated incoherent data acquisition pattern as well as a temporal regularization term. Acceleration factors of up to 7.3 were reached while image quality was preserved. While non-regularized iterative reconstruction led to a drop of 42.8% ± 7.5% in Contrast-to-Noise compared to the fully sampled reference, the proposed MDFCS method was able to achieve values of 90.5% ± 12.2% and to reproduce the flow curve behavior with high accuracy.
Identification of the Regions on the M110 Subunit of Protein Phosphatase 1M That Interact with the M21 Subunit and with Myosin (1997)

We have previously isolated a form of protein phosphatase-1 (PP1M) from avian smooth muscle myofibrils that is composed of the catalytic subunit of PP1 (PP1C) bound to an M-complex consisting of 110-kDa (M110) and 21-kDa (M21) subunits. The interaction of PP1C with an N-terminal region of the M110 subunit enhances the dephosphorylation of myosin and suppresses the dephosphorylation of other substrates [Alessi, D. R., MacDougall, L. K., Sola, M. M., Ikebe, M. & Cohen, P. (1992) Eur. J. Biochem. 210, 1023-1035; Chen, Y. H., Chen, M. X., Alessi, D. R., Campbell, D. G., Shanahan, C., Cohen, P. & Cohen, P. T. W. (1994) FEBS Lett. 356, 51-56; Johnson, D. F., Moorhead, G., Caudwell, F. B., Cohen, P., Chen, Y. H., Chen, M. X. & Cohen, P. T. W. (1996) Eur. J. Biochem. 239, 317-325]. In this paper, we establish that PP1M accounts for nearly all the myosin phosphatase activity in myofibrils, that the M110 and M21 subunits are present at similar concentrations in the myofibrillar fraction, and that these subunits are entirely bound to PP1. We demonstrate that the M21 subunit does not interact with PP1C, but with the C-terminal 72 residues of the M110 subunit, a region which is 43% identical to residues 87-161 of the M21 subunit. A fragment of the M21 subunit, M21-(M1-L146), which lacks the C-terminal leucine zipper, also bound to the M110 subunit, but two other fragments M21-(M1-E110) and M21-(E110-K186) did not. The M110 and M21 subunits were both found to be myosin-binding proteins. The C-terminal 291 residues of the M110 subunit, but not the C-terminal 72 residues, bound to myosin, but the N-terminal fragments M110-(M1-E309) and M110-(M1-S477) did not. Thus, the region of the M110 subunit that stimulates the dephosphorylation of myosin by PP1C is distinct from the region that targets PP1M to myosin. Remarkably, each myosin dimer was capable of binding about 20 mol M21 subunit and many of the M21-binding sites were located in the myosin rod domain. The potential significance of this observation is discussed.
PHOTOCHEMISTRY OF DNA USING 193 nm EXCIMER LASER RADIATION (1990)

Photoproducts in double-stranded DNA induced by 193 nm radiation have been investigated. Double-stranded, supercoiled pBR322 DNA in buffered aqueous solution was exposed to varying fluences of 193 nm radiation from an ArF excimer laser. The quantum yields for formation of cyclobutylpyrimidine dimers, frank strand breaks and alkali labile sites were calculated from the conversion of supercoiled (Form I) DNA to relaxed (Form II) DNA after treatment with Micrococcus luteus dimer-specific endonuclease, no treatment, or treatment with alkali and heat, respectively. The quantum yields were 1.65 (+/- 0.03) X 10(-3) for pyrimidine dimers, 9.4 (+/- 3.2) X 10(-5) for frank strand breaks and 9.6 (+/- 3.6) X 10(-5) for alkali labile sites. The quantum yields for pyrimidine dimers and strand breaks and alkali labile sites were not affected by 10 nM mannitol. The relative quantum yields for these DNA photoproducts induced by 193 nm radiation differed markedly from those produced by 254 nm radiation.