gebhart/patrepeval huggingface dataset:
First measurements of remaining shell areal density on the OMEGA laser using the Diagnostic for Areal Density (DAD) (2018)

A glass Cherenkov detector, called the Diagnostic for Areal Density (DAD), has been built and implemented at the OMEGA laser facility for measuring fusion gammas above 430 keV, from which remaining shell ⟨<i>ρR</i>⟩ <sub><i>abl</i></sub> can be determined. A proof-of-principle experiment is discussed, where signals from a surrogate gas Cherenkov detector are compared with reported values from the wedge range filter and charged particle spectrometer and found to correlate strongly. The design of the more compact port-based DAD diagnostic and results from the commissioning shots are then presented. Once absolutely calibrated, the DAD will be capable of reporting remaining shell ⟨<i>ρR</i>⟩ <sub><i>abl</i></sub> for plastic and glass capsules within minutes of a shot and with potentially higher precision than existing techniques.
Protein complex analysis: From raw protein lists to protein interaction networks (2015)

The elucidation of molecular interaction networks is one of the pivotal challenges in the study of biology. Affinity purification-mass spectrometry and other co-complex methods have become widely employed experimental techniques to identify protein complexes. These techniques typically suffer from a high number of false negatives and false positive contaminants due to technical shortcomings and purification biases. To support a diverse range of experimental designs and approaches, a large number of computational methods have been proposed to filter, infer and validate protein interaction networks from experimental pull-down MS data. Nevertheless, this expansion of available methods complicates the selection of the most optimal ones to support systems biology-driven knowledge extraction. In this review, we give an overview of the most commonly used computational methods to process and interpret co-complex results, and we discuss the issues and unsolved problems that still exist within the field. © 2015 Wiley Periodicals, Inc. Mass Spec Rev 36:600-614, 2017.
A Perpendicular Spin Torque Switching based MRAM for the 28 nm Technology Node (2007)

We report on a novel spin torque select MRAM with perpendicular anisotropy (P-ST-MRAM). The P-ST concept offers superior scalability performance at the 28 nm technology node compared to the conventional in-plane spin torque MRAM (I-ST-MRAM). The critical programming currents (~ 30 muA) are low, allowing a cell layout as small as 6 F2. In addition, data retention is significantly better for P-ST enabling a non-volatile, high density product for the 28 nm node. Estimations on write performance promise high write endurance and high write speed. Circuit simulations with improved read circuit demonstrate array read access time ~ 30 ns at sensing currents ~ 10 muA.
Revisiting the wire medium: an ideal resonant metalens (2011)

This article is the first one in a series of two dealing with the concept of a ‘resonant metalens’ we introduced recently. Here, we focus on the physics of a medium with finite dimensions consisting of a square lattice of parallel conducting wires arranged on a sub-wavelength scale. This medium supports electromagnetic fields that vary much faster than the operating wavelength. We show that such modes are dispersive due to the finiteness of the medium. Their dispersion relation is established in a simple way, a link with designer plasmons is made, and the canalization phenomenon is reinterpreted in the light of our model. We explain how to take advantage of this dispersion in order to code sub-wavelength wavefields in time. Finally, we show that the resonant nature of the medium ensures an efficient coupling of these modes with free space propagating waves and, thanks to the Purcell effect, with a source placed in the near field of the medium.
Enhancing Task Specific Ionic Liquids' Thermal Stability by Structural Modification (2007)

Submitted version of Bösmann, A., Schulz, P. &amp; Wasserscheid, P. Enhancing Task Specific Ionic Liquids’ Thermal Stability by Structural Modification. <em>Monatsh. Chem.</em> <strong>138</strong>, 1159–1161 (2007). https://doi.org/10.1007/s00706-007-0730-2
Optically Driven, RF Transmit Phased Array Antennas for Mobile Communications and Wireless Networks (2020)

This article introduces the use of optically fed, RF transmitting antennas for mobile communications and wireless networks. Motivation for the development of such antennas arises from the rapidly expanding allocations of electromagnetic spectrum by the Federal Communications Commission (FCC), which introduced spectral allocations extending up to 240 GHz. Because all electrical devices become lossy at such frequencies, photonic devices offer an attractive alternative. This article presents an overview of the use of photonic devices and systems for feeding and controlling RF phased array antennas for wireless communications. In particular, it introduces the concept of a current sheet as the ideal phase array antenna that offers a frequency‐independent impedance. The challenge has been the difficulty in designing a feed network capable of realizing such a dense array of current elements. To the extent that a photodetector is very small in comparison to RF wavelengths, it can serve as an ideal current source for a dense array. In addition, this article introduces not only broadband feed networks using photodetectors, but it also introduces novel feed architectures that offer significant control of the beam‐forming and data‐encoding to realize truly viable communication antennas.
Polymerization ofo‐quinodimethanes. V. Ionic polymerization ofo‐quinodimethanes generated by thermal isomerization of corresponding benzocyclobutenes (2007)

Abstract The ionic polymerization of substituted o ‐quinodimethanes via thermal isomerization of benzocyclobutenes is described. In the cationic polymerizations of 1‐methoxy‐ o ‐quinodimethane in the presence of various cationic initiators at 110 °C for 12 h, chain transfer reactions also considerably underwent besides the polymerization. Meanwhile, cationic polymerizations of 1‐trimethylsilyloxy‐ o ‐quinodimethane under the same conditions gave good yields of the corresponding polymer. Anionic polymerizations of 1‐cyano‐ o ‐quinodimethane in the presence of anionic initiators such as n ‐BuLi or t ‐BuOK were performed at various temperatures for 12 h. Good yields of hexane‐insoluble polymer, which was produced by anionic polymerization of corresponding o ‐quinodimethane as an intermediate, were obtained above 120 °C. © 2007 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 46: 844–850, 2008
The Processing of Ultrafine-Grained Materials Using High-Pressure Torsion (2007)

This DOI is not currently attached to any metadata records. DOIs can’t actually ever be deleted (they’re persistent), but sometimes our members create DOIs in error. We do have a process to approximate deletion which we follow only in rare cases where the DOI has been genuinely created in error, and most crucially, if the DOI has never been published anywhere online or in print and never otherwise distributed to or communicated with anyone (authors, readers, reviewers, etc.
Improvement on pattern matching method for hand-waving finger vein authentication (2017)

Recently, the application field of biometric authentication is expanding from small-scale service to wide-scale one such as big event venue, theme park, and so on. In these situations, high-speed calculation and smooth operation are required because of a large number of users. In order to apply finger vein authentication to above services, a walkthrough type finger vein authentication is effective. In our previous study, a hand waving finger vein authentication system was proposed [1]. However, it is hard for this system to achieve high-speed calculation and highly accurate authentication simultaneously. In this study, we propose an improved pattern matching method that make it possible to accelerate the calculation of the finger vein authentication by applying Scale-Invariant Feature Transform (SIFT).
Development of a Suitable Salt Form for a GPR40 Receptor Agonist (2010)

AMG 837 (1) is a novel GPR40 agonist selected for clinical development for the treatment of type 2 diabetes. A lysine salt was initially identified as a development form. However, due to the poor crystallinity and severe hygroscopicity of this form, investigations on the free acid form of the drug substance and salt screening were conducted to identify an acceptable physical form for long-term development. A sodium and calcium salt were identified as potentially viable phases, and polymorph screening was conducted on both. The quality attributes of the salts were then compared to determine which phase would be preferred for development.
ChemInform Abstract: Addition of 2,3‐Dihydro‐5‐furanyllithium to Diisopropyl Squarate as a Means for the Rapid Generation of Structurally Complex Oxygen‐ Containing Tetraquinane Networks. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Detection Of Key Change In Classical Piano Music. (2005)

[TODO] Add abstract here.
Convergence of SOR in MoM Analysis of Array Antenna (2005)

SUMMARY Convergence of the iterative method based on the successive overrelaxation (SOR) method is investigated to solve the matrix equation in the moment analysis of array antennas. It is found this method can be applied to the sub domain method of moments with fast convergence if the grouping technique is applied and the over-relaxation parameter is properly selected, and the computation time for solving the matrix equation can be reduced to be almost proportional to the second power of the
Low-power circuit advantages of the scaled accumulation FET (2003)

The trend toward higher clock frequencies has resulted in FETs being compared for their performance at the highest frequencies. Traditionally, the buried channel(BC) FET is considered to have more short channel effects than the normal surface channel inversion(SCI) FET and thus the BC FET is used only when absolutely needed. The same, more severe short channel effects behavior has been assumed for moderate to high-V/sub T/ FETs, which find use in ultra low-power applications. However, a careful investigation both at the transistor and circuit level, reveals that the BC FET is better than the SCI FET for moderate speed, ultra low-power applications.
Frontiers in cancer immunotherapy—a symposium report (2020)

Cancer immunotherapy has dramatically changed the approach to cancer treatment. The aim of targeting the immune system to recognize and destroy cancer cells has afforded many patients the prospect of achieving deep, long-term remission and potential cures. However, many challenges remain for achieving the goal of effective immunotherapy for all cancer patients. Checkpoint inhibitors have been able to achieve long-term responses in a minority of patients, yet improving response rates with combination therapies increases the possibility of toxicity. Chimeric antigen receptor T cells have demonstrated high response rates in hematological cancers, although most patients experience relapse. In addition, some cancers are notoriously immunologically "cold" and typically are not effective targets for immunotherapy. Overcoming these obstacles will require new strategies to improve upon the efficacy of current agents, identify biomarkers to select appropriate therapies, and discover new modalities to expand the accessibility of immunotherapy to additional tumor types and patient populations.
Growth of core (GaAs) / shell (functional oxide) nanowires (2016)

May, 16-19, 2016
Successes, failures and new perspectives of idiotypic vaccination for B-cell non-Hodgkin lymphomas (2013)

The idiotype of B-cell non-Hodgkin lymphomas has been intensively investigated for its proven immunogenicity as a promising cancer vaccine. Indeed, available data clearly indicate that these vaccines are able to induce tumor-specific immune responses and molecular remissions in patients with follicular lymphoma. However, only one of the three phase III trials performed so far demonstrated a prolonged disease-free survival in vaccinated patients. The observed failures have been mainly ascribed to defects in the study design and not to the limited efficacy of idiotype vaccines per se. Therefore, innovative and optimized idiotype-based vaccine formulations are being developed in order to overcome current limitations and improve the clinical benefit of this immunotherapeutic strategy. Among the most promising advances, the development of "off-the-shelf" vaccines appears of particular relevance, being potentially able to overcome the limitations related to the complex, time-consuming and expensive production of the individualized idiotypic vaccines currently used. Moreover, there is a pressing need to identify biomarkers suitable for the identification of the subset of patients who are most likely to benefit from vaccination. Recent findings also indicate that idiotypic vaccines may be safely and successfully used in additional clinical settings, including lymphoma patients after high-dose chemotherapy and autologous stem cell transplantation.
Interaction of Structured Light with a Chiral Plasmonic Metasurface: Giant Enhancement of Chiro-Optic Response (2018)

We propose an approach to achieve giant enhancement and broad spectral tunability of the chiro-optic response of plasmonic metasurfaces by exploiting interaction with complex light, endowed with both spin and orbital angular momentum. As a proof of principle, we employ full-wave computational analysis to investigate the response of a structured, circularly polarized transverse Laguerre-Gaussian beam incident on a chiral metasurface composed of a two-dimensional array of gold nanohelix meta-atoms. Our analysis reveals for the first time unprecedented amplification of circular dichroism that is a manifestation of the total angular momentum of the incident light being enantioselectively transferred to the medium. We also demonstrate that the spectral response of the meta-atoms can be designed to produce a rich manifold of narrow spectral lines with steep gradients. The approach proposed here opens up opportunities for new spectroscopic modalities to probe fundamental molecular structure and behavior, as well as unique, multiplexed biochemical sensing technologies, and a new class of engineered chiral metamaterials in the form of versatile ultrathin media with unmatched optical performance for a gamut of applications, including a new direction for spin photonics, exploiting high reflection contrast between opposite spins.
Abstract 73: Atrial Fibrillation-induced Changes in Left Atrial Hemodynamics Directly Impact the Thrombotic Potential of Human Primary Endothelial Cell Cultures (2013)

Thrombus formation in the left atrial appendage (LAA) of the heart is a source of stroke risk in patients with atrial fibrillation (Afib). Strategies to prevent thromboembolism from the LAA via restoration of normal rhythm or prevention of clot formation are limited by lack of adequate human surrogate systems that recapitulate the biology ex vivo. Endothelial cell phenotype and function in blood vessels and chambers of the heart are regulated in part by regional hemodynamics. Blood flow shear forces in the LAA are substantially altered during Afib. Thus, we hypothesized that Afib-induced alterations in hemodynamics directly impacts the thrombotic potential of the endothelium in the LAA. To test this, human primary aortic endothelial cell cultures were primed under hemodynamic shear forces simulating the human LAA during normal sinus rhythm for 24 hrs and continued under sinus rhythm or switched to simulate Afib for an additional 24 hrs. Compared to sustained sinus rhythm, Afib hemodynamics suppressed genes (qRTPCR) that define a healthy/quiescent endothelial cell phenotype (e.g. KLF2 and NOS3/eNOS) while inducing the pro-thrombotic gene F3 (tissue factor) and suppressing ADAMSTS13, MMP14 and TIMP2. To determine whether the observed molecular response produced a functional prothrombotic phenotype, hemodynamic primed aortic endothelial cells were exposed to dilute (~27% final concentration) human platelet-free plasma supplemented with Alexa488-labeled human fibrinogen, corn trypsin inhibitor and calcium. Cleavage of fibrinogen to fibrin and concomitant deposition on the endothelium was measured by quantitative confocal microscopy. When exposed to Afib hemodynamics, endothelial cells supported significant fibrin deposition that extended to greater depth (i.e., thicker) on the endothelium compared to sinus rhythm hemodynamics. In conclusion, we show for the first time a direct mechanistic link between changes in LAA hemodynamics associated with development of Afib and functional alterations in the thrombotic potential of the endothelium. This study produced a novel insight enabled by studying potential triggers of thrombosis in a context that more closely mimics the normal and pathological human in vivo environment.
Direct (Hetero)arylation Polymerization: An Effective Route to 3,4-Propylenedioxythiophene-Based Polymers with Low Residual Metal Content (2013)

We report the use of direct (hetero)arylation polymerizations (DHAP) as a means of obtaining 3,4-propylenedioxythiophene-based conjugated polymers for use in electrochromics. This method offers a rapid route to achieving polymers in high yields with simplified purification procedures and low residual metal content, as determined by inductive coupled plasma-mass spectrometry (ICP-MS). The studied polymers possess comparable electrochromic properties to those previously reported by our group, implying that their switching ability from a colored to a transmissive state is independent of the residual metallic impurities.
A Bipolar Pad in a 10-kHz 300-W Distributed IPT System for AGV Applications (2013)

This paper presents the magnetic analysis of a recently proposed multiple coil pad design, called the bipolar pad (BPP), in a distributed inductive power transfer (IPT) system for automatic guided vehicle (AGV) applications. The paper briefly discusses the magnetic design optimization procedure and then optimizes another recently proposed secondary pad design (generally used in lumped IPT systems), called the double-D quadrature pad (DDQP), for distributed AGV applications and compares its performance with the BPP. A four conductor single phase track topology is used here as primary. Both the pads discussed in this paper have already been shown to perform well in lumped IPT systems and hence the work presented in this paper highlights and validates the possibility of using these pads in mixed distributed/lumped IPT systems. A 3-D finite element modeling tool is used to evaluate and compare all the models presented in this paper. To validate these results, a prototype system is built with a BPP secondary driving a load through a controller circuit. A modification in the traditional control topology is proposed and shown to improve the overall system efficiency; before finally highlighting some of the practical design issues needed to be considered when building such a system.
Machine learning accelerates MD-based binding pose prediction between ligands and proteins (2017)

Supplementary data are available at Bioinformatics online.
The Role of Bacterial and Host Proteinases in Periodontal Disease (2006)

It is abundantly obvious that the uncontrolled degradation and/or activation of host defense pathways is the major pathway by which the periodontal pathogen P. gingivalis promotes its growth and proliferation. By being able to shed host receptors, degrade cytokines, and activate coagulation, complement, and kallikrein/kinin pathways it is clear that this organism has found a mechanism(s) to evade host defense and at the same time develop a system for cannibalizing host proteins for its own nutritional usage (Fig 2). Thus, it seems only logical that the development of inhibitors against these bacterial proteinases would be a useful method for negating their activities and making such pathogens more susceptible to attack by host phagocyte cells. In this respect, the structure of the truncated form of RGP has just been elucidated. Thus, it should only be a question of time before inhibitors to this enzyme will be developed and, hopefully, be used to reduce the pathologies associated with the development of periodontitis and/or eliminate the disease altogether.
Personnel Management of Researcher in Petrol Production Corporation: Take Research Institute of Diggingsin Middle of Sichuan of Southwest Filiale of Petrol China as Example (2004)

Because of stock limited company's stepping into the stock market, the task and aim of research institute of petroleum corporations have changed profoundly. The old personnel system, whose methods and ideas have not adopted to the corporations' building, faces the urgent demands of integral talents good at both study and production, researchers group that has the reasonable structure, managers understanding study and management. Can only we set up new ideas, build new mechanism, promote the excellent persons, optimize the structure of study group, innovate the ideas, method and system of management to solve the problems radically.
Association of Inflow Cannula Position with Left Ventricular Unloading and Clinical Outcomes in Patients with HeartMate II Left Ventricular Assist Device (2018)

The relationship between the HeartMate II left ventricular assist device (LVAD) position and pump thrombosis has been reported. However, further clinical implications of device position are unknown. This study aimed to investigate optimal device position for better left ventricular (LV) unloading and patient prognosis. Patients undergoing a ramp test with right heart catheterization after HeartMate II LVAD implantation were enrolled to this study. Device position was quantified from the chest X-ray obtained at the time of the ramp test: (1) inflow cannula angle relative to horizontal line, (2) pump angle relative to spine, (3) pump depth, (4) angle between inflow cannula and pump, and (5) angle between pump and outflow graft. LV unloading was assessed by pulmonary capillary wedge pressure at set LVAD speed. Fifty-four patients (60 years old and 34 male [63%]) were enrolled. Nobody experienced device malfunction during the study period. Increased LV unloading (i.e., lower pulmonary capillary wedge pressure) was associated with a narrower inflow cannula angle relative to horizontal line. Inflow cannula angle <75° was associated with higher 1 year heart failure readmission-free survival rate (p < 0.05, hazards ratio 7.56 [95% confidence interval 2.32-24.7]). In conclusion, HeartMate II LVAD inflow cannula position was associated with LV unloading and patient prognosis. Prospective studies to ensure optimal device positioning and target better clinical outcomes are warranted.
Antibiotics from basidiomycetes. XXXII. Strobilurin E: A new cytostatic and antifungal (E)-.BETA.-methoxyacrylate antibiotic from Crepidotus fulvotomentosus Peck. (1990)

Strobilurin E is a novel antibiotic of the (E)-beta-methoxyacrylate (MOA) class produced by mycelial cultures of the agaric Crepidotus fulvotomentosus. In addition to an inhibition of fungal respiration, a feature of all MOA-antibiotics, the compound exhibits very high cytostatic activities which are accompanied by reversible morphological alterations of the cells.