gebhart/patrepeval huggingface dataset:
Correction to: Hydrothermally induced changes in the properties of MFC and characterization of the low molar mass degradation products (2019)

In the original publication, the less than symbol (<) was mistakenly processed as greater than symbol (>) in Tables 2 and 4.
Surveillance of systemic trafficking of macrophages induced by UHMWPE particles in nude mice by noninvasive imaging (2010)

Macrophages constitute a major part of the cell response to wear particles produced at articulating and nonarticulating interfaces of joint replacements. This foreign body reaction can result in periprosthetic osteolysis and implant loosening. We demonstrate that ultra-high molecular weight polyethylene (UHMWPE) particles induce systemic trafficking of macrophages by noninvasive in vivo imaging and immunohistochemistry. The distal femora of nude mice were injected with 60 mg/mL UHMWPE suspension or saline alone. Reporter RAW264.7 macrophages that stably expressed the bioluminescent reporter gene and the fluorescence reporter gene were injected intravenously. Bioluminescence imaging was performed using an in vivo imaging system immediately after macrophage injection and at 2-day intervals. Compared with the nonoperated contralateral femora, at day 4, 6, and 8, the bioluminescent signal of femora containing UHMWPE suspension increased 1.30 +/- 0.09-, 2.36 +/- 0.92-, and 10.32 +/- 7.61-fold, respectively. The values at same time points for saline-injected control group were 1.08 +/- 0.07-, 1.14 +/- 0.27-, and 1.14 +/- 0.35-fold, respectively. The relative bioluminescence of the UHMWPE group was higher at all postinjection days and significantly greater than the saline group at day 8 (p < 0.05). Histological analysis confirmed the presence of reporter macrophages within the medullary canal of mice with implanted UHMWPE particles. The presence of UHMWPE particles induced enhanced bone remodeling activity. Clinically relevant UHMWPE particles stimulated the systemic recruitment of macrophages during an early time course using the murine femoral implant model. Interference with systemic macrophage trafficking may potentially mitigate UHMWPE particle-induced periprosthetic osteolysis.
Supplementary Figure 1 from Lrig1 Is an Estrogen-Regulated Growth Suppressor and Correlates with Longer Relapse-Free Survival in ERα-Positive Breast Cancer (2023)

&lt;p&gt;Pdf file - 965K&lt;/p&gt;
Does hydrogen change the fullerenelike structure in CNx thin films? (2009)

The authors have reported the structure of the nanoclusters in carbon nitride thin films before [D. Roy et al., Phys. Rev. B 70, 035406 (2004)]. In this work, effects of the addition of hydrogen in the deposition gas mixture on the structures of carbon nitride thin films prepared by magnetron sputtering were investigated using Raman spectroscopy. Raman measurements showed that the structures of carbon nanoclusters remained unaffected by the addition of hydrogen in the carbon nitride films. On the other hand, the structures of amorphous thin films were affected by the addition of hydrogen in the deposition gas mixture. These are explained in terms of changes in the ratios of the D-peak to the G-peak intensities and shifts in the G-peak centers.
Proofs that yield nothing but their validity or all languages in NP have zero-knowledge proof systems (1991)

In this paper the generality and wide applicability of Zero-knowledge proofs, a notion introduced by Goldwasser, Micali, and Rackoff is demonstrated. These are probabilistic and interactive proofs that, for the members of a language, efficiently demonstrate membership in the language without conveying any additional knowledge. All previously known zero-knowledge proofs were only for number-theoretic languages in NP fl CONP. Under the assumption that secure encryption functions exist or by using &amp;quot;physical means for hiding information,&amp;quot; it is shown that all languages in NP have zero-knowledge proofs. Loosely speaking, it is possible to demonstrate that a CNF formula is satisfiable without revealing any other property of the formula, in particular, without yielding neither a
ChemInform Abstract: Pentanidium‐Catalyzed Enantioselective α‐Hydroxylation of Oxindoles Using Molecular Oxygen. (2013)

Abstract Hydroperoxide oxindoles are formed as by‐products.
Feedback stabilization of nonlinear systems: a path space iteration approach (2002)

We consider the feedback stabilization of nonlinear systems. The design methodology is based on a class of iterative methods, which has previously been proposed for the path planning and feedback stabilization of nonholonomic systems. We show that this scheme guarantees the closed loop asymptotic stability for a class of nonlinear systems.
Figures of merit of avalanche-mode silicon LEDs (2019)

The silicon avalanche-mode light-emitting diode (AMLED) opens a route for on-chip opto-electronic applications in standard CMOS, both due to its relatively broad spectral overlap with the spectral responsivity of silicon photodiodes and due to its high speed capability. This work presents closed form models for the key figures of merit (FOMs) of AMLEDs, namely, current (or power) density, cut-off frequency, radiative efficiency, and specifically for optical data communication energy cost per photon. Their derivations are based on one-dimensional analyses of an abrupt single-sided (p<sup>+</sup>n or n<sup>+</sup>p) junction and of a p-i-n diode. TCAD simulations for optimized device structures, including the recently reported superjunction (SJ) LED, were performed to validate the model. Measurements on single-sided abrupt junctions and SJ diodes are shown to validate some of the modelled trends. The results show that a p-i-n or an SJ diode is favorable to a conventional single-sided junction diode for the AMLED design. In addition, as confirmed for conventional AMLEDs by earlier reports, the results indicate that for a yet higher efficiency the carrier supply should be increased. For this a combination of a separate minority carrier injector and SJLED is proposed, referred to as the injection-avalanche CMOS SJLED. However, more experimental optical data (e.g., absolute photon flux) are needed for a more accurate model validation.
RideSense: Towards ticketless transportation (2016)

Imagine a transportation system in which passengers simply get on/off without any explicit ticketing operation. Yet, the system tracks usage and charges passengers. Such a system will not only be more convenient and efficient, but also be more conducive for analytics, than existing systems. Towards that goal, we exploit the opportunity that people are carrying sensor-equipped smart devices, and their motion trajectories/patterns and experienced environment can be measured continuously. Assuming that vehicles are also equipped with such sensors (perhaps fixed devices or smart devices carried by drivers), the vehicles' motion and the experienced environment characteristics can also be recorded and uploaded to cloud. Under these assumptions, we hypothesize that the motion/environment sensed by a passenger's smart device correlates strongly with that of the vehicle she is traveling in and is distinct from that of other vehicles and/or other traces of the same vehicle. In this paper, we expand on this intuition and develop a system, called RideSense, that matches a passenger's sensor trace against the traces of buses in that area, to determine which bus, when she has taken and where she gets on/off. Our evaluation of RideSense, with 20+ hours of traces from 5 bus lines in our area, shows that it achieves an accuracy of 84~98%, depending on the choice of sensors and their features, positions of the passengers' phones and the metrics of measurement. These results, while far from conclusive, offer confidence that ticketless public transportation may indeed be a possibility in smart cities of the future.
What constitutes an effective and efficient package of services for the prevention, diagnosis, treatment and care of tuberculosis among refugees and migrants in the WHO European Region? : Themed issues on migration and health, VIII (2018)

The WHO European Region has faced high rates of external and internal migration in recent years, with concerns that this is contributing to the burden of tuberculosis (TB), multidrug-resistant TB (MDR-TB) and TB/HIV coinfection in some countries. This report examines evidence of effective and efficient service packages for the prevention, diagnosis and treatment of TB to inform strategies to address the TB burden in refugee and migrant populations. Significant regional variations were identified in both migration levels and TB burden in refugees and migrants, as well as in approaches to TB control, with low quality of evidence in many cases. While it is unlikely that a single strategy/package will be effective for all situations, the evidence highlights some common approaches that could guide policy-making and service development. TB elimination targets for the Region will not be met unless inequalities in access to screening and treatment for migrants are addressed, alongside efforts to tackle TB globally.
Vaginal or laparoscopic hysterectomy: Do perioperative outcomes differ? A propensity score‐matched analysis (2019)

Both VH and LH have overall favorable perioperative outcomes; however, LH is associated with lower blood loss and a shorter hospital stay. The results support the trend toward increasing rates of laparoscopic approach to hysterectomy when appropriate.
Improved Latency Performance with GSM/EDGE Continued Evolution (2006)

The world's largest and most widespread cellular technology today is GSM/EDGE. EDGE is capable of offering an attractive solution for 3 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">rd</sup> generation cellular services in existing GSM networks. However, the introduction of new and more delay sensitive services may require improved latency performance. Reducing the delay and increasing the bandwidth efficiency in EDGE systems is important for services with stringent latency requirements, such as conversational VoIP, but will be beneficial also to other services. Proposed is to reduce the transmission time interval from 20 ms to 10 ms, in combination with novel procedures for faster feedback. Simulation results show that LLC delays may be reduced by 20-40% depending on traffic scenario. Furthermore, channel resource requirements for VoIP could be substantially reduced.
Efficient time-recursive implementation of matched filterbank spectral estimators (2005)

In this paper, we present a computationally efficient sliding window time updating of the Capon and amplitude and phase estimation (APES) matched filterbank spectral estimators based on the time-variant displacement structure of the data covariance matrix. The presented algorithm forms a natural extension of the most computationally efficient algorithm to date, and offers a significant computational gain as compared to the computational complexity associated with the batch re-evaluation of the spectral estimates for each time-update. Furthermore, through simulations, the algorithm is found to be numerically superior to the time-updated spectral estimate formed from directly updating the data covariance matrix.
Compensation of cable radiation in measurement of HF patterns (2014)

This paper details a simple compensation method for measuring radiation patterns in the HF band. Measured patterns have ripples of several decibels that are not a product of the antenna but rather radiation from the feed cable, as suggested from computer simulation. By assuming the feed cable is an independent vertically polarized radiator and making a third measurement, these ripples from both vertically and horizontally polarized patterns can be partially removed.
Small Pore Aluminosilicate EMM-37: Synthesis and Structure Determination Using Continuous Rotation Electron Diffraction (2019)

A new aluminosilicate zeolite, denoted EMM-37, with a 3D small pore channel system, has been synthesized using a diquaternary ammonium molecule as the structure directing agent (SDA) and metakaolin as the aluminum source. The structures of both <i>as-made</i> and calcined forms of EMM-37 were solved and refined using continuous rotation electron diffraction (cRED) data. cRED is a powerful method for the collection of 3D electron diffraction data from submicron- and nanosized crystals, which allows for successful solution and refinement of complex structures in symmetry as low as <i>P</i>1̅.
Live-cell imaging of glucose-induced metabolic coupling of β and α cell metabolism in health and type 2 diabetes (2021)

Type 2 diabetes is characterized by β and α cell dysfunction. We used phasor-FLIM (Fluorescence Lifetime Imaging Microscopy) to monitor oxidative phosphorylation and glycolysis in living islet cells before and after glucose stimulation. In healthy cells, glucose enhanced oxidative phosphorylation in β cells and suppressed oxidative phosphorylation in α cells. In Type 2 diabetes, glucose increased glycolysis in β cells, and only partially suppressed oxidative phosphorylation in α cells. FLIM uncovers key perturbations in glucose induced metabolism in living islet cells and provides a sensitive tool for drug discovery in diabetes.
An ultra-low-power monitoring system for inductively coupled biomedical implants (2013)

In this paper, an ultra-low-power system for wireless monitoring of inductively coupled biomedical implants is presented. The system is fully integrated and composed of custom rectifier, alignment and monitoring circuits with enhanced performance. The proposed system is described in the context of a smart-stent system that monitors the re-narrowing of blood vessels at the smart-stent site. The building blocks of the system are designed and simulated in a 0.13-μm CMOS technology. Simulation results for the monitoring system show that the proposed rectifier provides 53% power conversion efficiency (PCE) for -10.36 dBm input power (in the alignment mode) and 62% PCE for -4.06 dBm input power (in the monitoring mode). The alignment unit is capable of operating by drawing a 12 μA from a supply voltage as low as 0.6 V and the monitoring circuit consumes as low as 176 μW.
The multivalent glyconanoparticles as inhibitors of cytokine bioactivity (2015)

International audience
Coal gasification: scale-up factors in the H coal process (1973)

Some data on scale-up obtained at Hydrocarbon Research, Inc. on the commercialization of the H-Coal process are discussed. Development on the process was conducted on bench-scale and process development units. The bench units use reactors about 3.4 in. dia and handle about 25 lbs coal per day. The process development unit (PDU) reactor is 8 1/2 in. dia and handles 2.5 tons/ day of coal feed, a scale-up factor of about 200. The next unit will be a prototype with a 4.5 ft dia reactor with a scale-up factor of 100 from the process unit. The commercial-size reactors will be a scale-up of 10 from the prototype. (MCW)
A Novel Tendon Driven 5-Bar Linkage With a Large Isotropic Workspace (1999)

Abstract An innovative, tension-tendon drive system is proposed to increase the kinematically isotropic workspace and the average force transmission ratio of the closed chain 5-bar linkage. Tendons ran from the grounded actuators all along the mechanism closed chain and terminate on the ground. In this way, each of the two actuators transmits torques to all the five joints of the mechanism. A careful choice of the radii of the joint pulleys which route the tendons allows to improve the global kinematic isotropy performance up to 1.5.3 times and the average force transmission ratio up to 2.97 times with respect to drive of base joints. The advantages and disadvantages of such a system for the realization of a Highly Isotropic Haptic Interface are discussed.
Mechanically Robust Hydrophobized Double Network Hydrogels for Water Purification (2021)

Water swollen polymer networks are attractive for applications ranging from tissue regeneration to water purification. For water purification, charged polymers provide excellent ion separation properties. However, many ion exchange membranes (IEMs) are brittle, necessitating the use of thick support materials that ultimately decrease throughput. To this end, a series of double network hydrogels (DNHs), synthesized with varied composition to decrease water content, are examined as robust membrane materials for water purification. One network contains fixed anionic charges, while the other comprises a copolymer with different ratios of hydrophobic ethyl acrylate (EA) and hydrophilic dimethyl acrylamide (DMA) repeat units. Characterizing water content and mechanical performance in free standing DNH films reveals a ~5× decrease in water content, while increasing ultimate stress and strain by ~3.5× and ~4.5× for 90:5 EA:DMA relative to pure DMA. Salt transport properties relevant to water purification, including permeability, solubility, and diffusivity, are measured and show improved performance upon reducing water content. Overall, the ability to simultaneously reduce water content, increase mechanical integrity, and decrease salt transport rates highlights the potential of DNHs for membrane applications.
Overview of Antiplatelet Therapy (2016)

Platelets play a key role in arterial thrombosis (Fig. 1), where platelet activation and aggregation are the proximate events associated with acute coronary syndromes (ACS), stroke, and peripheral artery disease (PAD) (1-7). Platelet adhesion to injured vascular endothelium leads to platelet activation, which is further amplified by various platelet agonists, including arachidonic acid, thromboxane A2, adenosine disphosphate (ADP), thrombin, serotonin, and collagen (6-8). Aspirin was the first antiplatelet drug to provide insight into the role of platelets in health and disease (7,9). Since its development in 1899 and subsequent elucidation of mechanism of action, thromboxane A2 blockade has been one of the most well-known antiplatelet paradigms (9). Aspirin inhibits the formation of thromboxane by irreversibly inhibiting COX-1 via acetylation of the serine-529 peptide, the requisite site for the formation of thromboxane from arachidonic acid. It was not until the late 1970s that aspirin was widely recognized for its therapeutic benefit in cardiovascular disease (3,10). Aspirin is known to reduce the risk of myocardial infarction (MI), lower the risk of developing ischemic stroke, and decrease mortality in patients with vascular disease (11). Aspirin is presently recommended for the management of acute MI and unstable angina and is an effective therapeutic agent for secondary prevention of ischemic events (Fig. 2) (12,13).
Appendix 2: System Cleaning and Passivation Treatment (2002)

This Appendix contains sections titled: Background Information Reagents Preparation of the System Passivation of System Equilibration of System Passivation of Injection Port and Injection Needle References
Wireless Nanobioelectronics for Electrical Intracellular Sensing (2019)

For the field of bioelectronics to make an impact on healthcare, there is an urgent requirement for the development of “wireless” electronic systems to enable modulation of chemistry inside of cells. Herein we report on an intracellular wireless electronic communication system. This is based on modulating the electrochemistry on gold nanoparticles without the nanoparticles having any physical electrical connection to a power supply at relatively low externally applied potentials. The system is made functional by modifying water-soluble gold nanoparticles (ws-AuNPs) with a Zn(II) meso-tetrakis(4-carboxyphenyl)porphyrin sodium salt (Na-ZnTCPP). Na-ZnTCPP modified ws-AuNPs are taken up by cells and are shown to be noncytotoxic. It is demonstrated that the redox state of the Zn-porphyrin modified gold nanoparticles is controlled, and a fluorescent output can be used to measure this during the application of an external electrical potential. When the porphyrin modified nanoparticles were located intracellularly and external potentials were applied, the same effect was observed. This provides an attractive “wireless” approach to develop bioelectronic devices for modulating and sensing cellular behavior.
Accelerator-tandem with vacuum insulation as the basis of a medical complex for the treatment of malignant tumors using boron neutron capture therapy and a customs complex for remote detection of explosives (2006)

УСКОРИТЕЛЬ-ТАНДЕМ С ВАКУУМНОЙ ИЗОЛЯЦИЕЙ КАК ОСНОВА МЕДИЦИНСКОГО КОМПЛЕКСА ДЛЯ ЛЕЧЕНИЯ ЗЛОКАЧЕСТВЕННЫХ ОПУХОЛЕЙ МЕТОДОМ БОРНЕЙТРОНОЗАХВАТНОЙ ТЕРАПИИ И ТАМОЖЕННОГО КОМПЛЕКСА ДЛЯ ДИСТАНЦИОННОГО ОБНАРУЖЕНИЯ ВЗРЫВЧАТЫХ ВЕЩЕСТВВ статье описана конструкция и области применения оригинального протонного ускорителя с вакуумной изо
Indistinguishable single photons from a single quantum dot microcavity (2003)

A single-photon device based on a semiconductor quantum dot embedded in an optical microcavity is described. The spontaneous emission lifetime, multi-photon suppression, and spectral linewidth are measured. It is then shown that consecutively emitted photons possess a large degree of quantum-mechanical indistinguishability, with a mean wave-packet overlap as large as 0.8. This demonstration is accomplished through a Hong-Ou-Mandel-type two-photon interference experiment.
Accurate Measurement of Postprandial Glucose Turnover: Why Is It Difficult and How Can It Be Done (Relatively) Simply? (2016)

Fasting hyperglycemia occurs when an excessive rate of endogenous glucose production (EGP) is not accompanied by an adequate compensatory increase in the rate of glucose disappearance (Rd). The situation following food ingestion is more complex as the amount of glucose that reaches the circulation for disposal is a function of the systemic rate of appearance of the ingested glucose (referred to as the rate of meal appearance [Rameal]), the pattern and degree of suppression of EGP, and the rapidity of stimulation of the Rd In an effort to measure these processes, Steele et al. proposed what has come to be referred to as the dual-tracer method in which the ingested glucose is labeled with one tracer while a second tracer is infused intravenously at a constant rate. Unfortunately, subsequent studies have shown that although this approach is technically simple, the marked changes in plasma specific activity or the tracer-to-tracee ratio, if stable tracers are used, introduce a substantial error in the calculation of Rameal, EGP, and Rd, thereby leading to incorrect and at times misleading results. This Perspective discusses the causes of these so-called "nonsteady-state" errors and how they can be avoided by the use of the triple-tracer approach.
Simultaneous optical and acoustical observations of contrast agents (2002)

The increasing interest in the use of encapsulated microbubbles for ultrasound contrast agents and drug delivery mechanisms requires an understanding of the insonified microbubble on a microscopic scale. With the use of a video microscopy system coupled to either a microscopic ultrasound flow phantom or a chamber for insonifying stationary bubbles, the authors show that ultrasound has significant effects on encapsulated microbubbles. A train of ultrasound pulses can alter the structure of an albumin-shelled bubble or instigate various mechanisms of bubble destruction. Ultrasonic transmission also produces a primary radiation force which can displace contrast agents with each acoustic pulse, and the authors demonstrate this in-vivo as well as in-vitro. Secondary radiation force is shown to cause changes in effective scatterer size, echo characteristics, and persistence.