gebhart/patrepeval huggingface dataset:
Double-pulsed XeCl excimer laser etching of polyimide (1990)

We have studied changes in the ablation threshold of polyimide by combining two subthreshold XeCl excimer laser pulses with a set time delay. Initially overlapping, the pulse pair had a combined fluence above the ablation threshold for the polymer. When the two pulses were separated in time, cessation of etching occurred in a fashion that was more intensity-dependent than fluence-dependent. For pairs of pulses whose combined fluence was near the fluence threshold quoted in the literature, separation of the pulses resulted in an unusual initiation, cessation, and reinitiation of etching of the polymer surface. In the case of the reinitiated etching, we observed a large deposition of carboneous residue about debris particles on the surface. Based on a thermal model, the appearance of the large amount of carboneous residue coincided with a heat pulse generated by the first laser pulse that was above the thermal-degradation temperature of the polyimide. We think that this temporally dependent preferential etching is caused by an atmosphere of thermal-degradation products above the target surface that photo-dissociates upon receipt of the second pulse. A comparison of subthreshold fluence etching with etch rates generated by pulses with fluences above the threshold will also be presented.
Influence of device dimension and gate recess on the characteristics of AlGaN/GaN high electron mobility transistors (2012)

Abstract In this article, a gate recessed AlGaN/GaN high electron mobility transistor (HEMT) was developed using 4‐in. compound semiconductor process. We designed and fabricated four types of AlGaN/GaN HEMT to characterize the performance of devices. The effects of the gate recess depth and the device dimension of AlGaN/GaN HEMT are demonstrated. We present the scaling effect of the source‐gate and the drain‐gate enhancing the drain current and the transconductance. In addition, the current collapse was measured to estimate the trap effect in the surface and the buffer layer. Moreover, the comparison of RF performance of HEMT with different structure designs was performed. Based on these results, the optimization and the improvement of gate recessed GaN devices can be defined. © 2012 Wiley Periodicals, Inc. Microwave Opt Technol Lett 54:2103–2106, 2012; View this article online at wileyonlinelibrary.com. DOI 10.1002/mop.27036
Channel Estimation Based on Comb-Type Pilot Structure in OFDM System with Null Subcarriers (2007)

This paper analyzes the degradation effect of null subcarriers in orthogonal frequency division multiplexing (OFDM) systems on the time-domain maximum likelihood (ML) estimation performance. The analysis is used as the basis for a proposal for a new channel estimation method that can overcome performance degradation caused by null subcarriers. The accuracy of the proposed channel estimation is guaranteed by using an interpolation of the estimated channel in the frequency domain that comes before the channel estimation in the time domain.
Mechanochromism and Strain‐Induced Crystallization in Thiol‐yne‐Derived Stereoelastomers (2023)

Most elastomers undergo strain-induced crystallization (SIC) under tension; as individual chains are held rigidly in a fixed position by an applied strain, their alignment along the strain field results in a shift from strain-hardening (SH) to SIC. A similar degree of stretching is associated with the tension necessary to accelerate mechanically coupled, covalent chemical responses of mechanophores in overstretched chains, raising the possibility of an interplay between the macroscopic response of SIC and the molecular response of mechanophore activation. Here, thiol-yne-derived stereoelastomers doped covalently with a dipropiolate-derivatized spiropyran (SP) mechanophore (0.25-0.38 mol%) are reported. The material properties of SP-containing films are consistent with undoped controls, indicating that the SP is a reporter of the mechanical state of the polymer. Uniaxial tensile tests reveal correlations between mechanochromism and SIC, which are strain-rate-dependent. When mechanochromic films are stretched slowly to the point of mechanophore activation, the covalently tethered mechanophore remains trapped in a force-activated state, even after the applied stress is removed. Mechanophore reversion kinetics correlate with the applied strain rate, resulting in highly tunable decoloration rates. Because these polymers are not covalently crosslinked, they are recyclable by melt-pressing into new films, increasing their potential range of strain-sensing, morphology-sensing, and shape-memory applications.
Electron spin resonance investigation of ultra-small double walled carbon nanotubes embedded in zeolite nanochannels (2011)

We report on the low temperature electron spin resonance (ESR) properties of ultra-small (0.45 nm) double walled carbon nanotubes (DWCNTs) embedded in zeolite nanochannels. An isotropic ESR signal is observed at g(c) = 2.002 77 with the spin density (S = 1/2) ∼ 10(19) g(-1), which is suggested to originate from the carbon related point defects in the DWCNTs. Measurements of the ESR line width and signal intensity as a function of temperature indicate that the spins are of a localized nature as opposed to the conduction type electrons observed in large diameter CNTs. The results are consistent with the suggestion that electrons are trapped at interstitial defects. The observed linear frequency dependence of the ESR line width of embedded DWCNTs points to 'strain' as the prime source of broadening. By contrast, the study of free standing DWCNTs shows the presence of a distinctly superlinear frequency dependence of the signal width at low temperatures. The possible origin of the frequency dependence is discussed.
The role of “contrast enhancement” in the detection and appearance of visual contours (1998)

We test the proposition that the appearance and detection of visual contours is based on an increase in the perceived contrast of contour elements. First we show that detection of contours is quite possible in the presence of very high levels of variability in contrast. Second we show that inclusion in a contour does not induce Gabor patches to appear to be of higher contrast than patches outside of a contour. These results suggest that, contrary to a number of current models, contrast or its assumed physiological correlate (the mean firing rate of early cortical neurons) is not the determining information for identifying the contour.
Hybrid silicon lasers: progress and perspectives (2012)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text M. Fiorentino, D. Liang, G. Kuczveil, and R. G. Beausoleil, "Hybrid silicon lasers: progress and perspectives," in Asia Communications and Photonics Conference, OSA Technical Digest (online) (Optica Publishing Group, 2012), paper AF3B.5. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer’s disease (2023)

Discoidin Domain Receptor (DDR)-1 is activated by collagen. Nilotinib is a tyrosine kinase inhibitor that is FDA-approved for leukemia and potently inhibits DDR-1. Individuals diagnosed with mild-moderate Alzheimer's disease (AD) treated with nilotinib (versus placebo) for 12 months showed reduction of amyloid plaque and cerebrospinal fluid (CSF) amyloid, and attenuation of hippocampal volume loss. However, the mechanisms are unclear. Here, we explored unbiased next generation whole genome miRNA sequencing from AD patients CSF and miRNAs were matched with their corresponding mRNAs using gene ontology. Changes in CSF miRNAs were confirmed via measurement of CSF DDR1 activity and plasma levels of AD biomarkers. Approximately 1050 miRNAs are detected in the CSF but only 17 miRNAs are specifically altered between baseline and 12-month treatment with nilotinib versus placebo. Treatment with nilotinib significantly reduces collagen and DDR1 gene expression (upregulated in AD brain), in association with inhibition of CSF DDR1. Pro-inflammatory cytokines, including interleukins and chemokines are reduced along with caspase-3 gene expression. Specific genes that indicate vascular fibrosis, e.g., collagen, Transforming Growth Factors (TGFs) and Tissue Inhibitors of Metalloproteases (TIMPs) are altered by DDR1 inhibition with nilotinib. Specific changes in vesicular transport, including the neurotransmitters dopamine and acetylcholine, and autophagy genes, including ATGs, indicate facilitation of autophagic flux and cellular trafficking. Inhibition of DDR1 with nilotinib may be a safe and effective adjunct treatment strategy involving an oral drug that enters the CNS and adequately engages its target. DDR1 inhibition with nilotinib exhibits multi-modal effects not only on amyloid and tau clearance but also on anti-inflammatory markers that may reduce cerebrovascular fibrosis.
Ultrafast Response and Superior Optical Limiting Effects of Planar “Open” Heterothiometallic Clusters (2002)

Heterothiometallic clusters with a planar open skeleton (see Figure) show a better optical limiting performance than C60 towards picosecond laser pulses and are promising optical-power limiting materials. The influence of the cluster skeletons and the constitutent elements in the clusters on the optical-power limiting properties as well as the influence of the optical nonlinearities upon irradiation with pico- and nanosecond pulsed lasers are discussed.
Prediction of Bubble Point Pressure Using Artificial Intelligence AI Techniques (2016)

Abstract It is very important to determine or predict the bubble point pressure (BPP) with high accuracy in petroleum industry. Laboratory measurement of the BPP requires collecting actual samples from the bottom of the wellbore and simulates the reservoir conditions at the lab. This operation takes long time and high cost. To overcome this issue, many empirical correlations were developed to predict the BPP with wide range of average percent error. In this research, we will use artificial intelligent (AI) techniques to predict the bubble point pressure using published data (760 data sets). Two different AI techniques will be used, artificial neural network (ANN) (back propagation network (BPN) and radial basis functions networks (RBF)), and fuzzy logic tool (FL) to develop the model. The obtained results will be compared with the available correlations in the literature. The results obtained showed that all AI models were able to predict the bubble point pressure with a high accuracy. The new fuzzy logic (FL) model outperforms all the artificial neural network models and the most common published empirical correlations. BPN, RBF and FL models provide predictions of bubble point pressure with correlation coefficient of 0.9926, 0.9969, and 0.9995, respectively.
Synthesis, characterization, and field‐effect transistor performance of poly[2,6‐bis(3‐tridecanoxythiophen‐2‐yl)benzo[1,2‐b;4,5‐b′]dithiophene] (2010)

Abstract A new copolymer of benzo[1,2‐b:4,5‐b′]dithiophene and 3,3′‐bis(tridecanoxy)‐5,5′‐bithiophene was synthesized through Stille copolymerization. The bis‐(3‐alkoxythiophene) monomer was synthesized through a silver fluoride mediated, palladium‐catalyzed cross‐coupling, in which bromide functional groups were preserved instead of consumed. The copolymer has been characterized and applied in field‐effect transistors, giving a hole mobility of 2 × 10 −3 cm 2 /Vs and an on/off ratio &gt;10 6 , with negligible hysteresis, on standard silicon substrates. © 2010 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 48: 1973–1978, 2010
Two members of a conserved family of nuclear phosphoproteins are involved in pre-mRNA splicing. (1992)

Monoclonal antibody 104 recognizes a subset of amphibian nuclear granules (B-snurposomes) and active sites of RNA polymerase II transcription in vertebrates and invertebrates. Monoclonal antibody 104 reacts with a set of nuclear serine- and arginine-rich phosphoproteins (SR family) with strikingly conserved apparent molecular masses. The most abundant family members in human (SRp33) and Drosophila (SRp55) cell lines can replace one another as essential splicing factors in a human cell-free system. Each of these polypeptides can functionally replace human SF2, an essential splicing factor that also regulates 5' splice site selection of alternatively spliced pre-mRNAs in vitro. Drosophila SRp55 also functions as an alternative splicing factor in the human cell-free system. Analysis of cloned cDNAs shows that SRp55 and SF2 are highly related and reveals regions of similarity to genetically defined regulators of alternative splicing in Drosophila. These results suggest that the conserved SR family of phosphoproteins, which includes SRp55 and SF2, is involved in constitutive pre-mRNA splicing and in the specificity of alternative splice site selection.
Performances of Small-Sized Generator of Ozone-Dissolved Water Using Boron-Doped Diamond Electrodes (2011)

A new electrochemical generator of ozone-dissolved water, which is comprised of an electro-conductive diamond electrode and an ion exchange membrane, was evaluated using tap water as source solution, in order to confirm general versatility. Although the current efficiency of tap water became lower than that obtained in the case of pure water, ozone-dissolved water of over 1 mg/L could be produced. The durability was found to be longer than 300 h. Disinfection power using source water containing small amounts of surfactant became 10 times larger than that of water with no surfactant. Medical tests conducted with pet animals revealed that the treatment using ozone-dissolved water was clearly effective for anti-inflammatory diseases.
Temporal Scalability of Dynamic Volume Data Using Mesh Compensated Wavelet Lifting (2017)

Due to their high resolution, dynamic medical 2D+t and 3D+t volumes from computed tomography (CT) and magnetic resonance tomography (MR) reach a size which makes them very unhandy for teleradiologic applications. A lossless scalable representation offers the advantage of a down-scaled version which can be used for orientation or previewing, while the remaining information for reconstructing the full resolution is transmitted on demand. The wavelet transform offers the desired scalability. A very high quality of the lowpass sub-band is crucial in order to use it as a down-scaled representation. We propose an approach based on compensated wavelet lifting for obtaining a scalable representation of dynamic CT and MR volumes with very high quality. The mesh compensation is feasible to model the displacement in dynamic volumes which is mainly given by expansion and contraction of tissue over time. To achieve this, we propose an optimized estimation of the mesh compensation parameters to optimally fit for dynamic volumes. Within the lifting structure, the inversion of the motion compensation is crucial in the update step. We propose to take this inversion directly into account during the estimation step and can improve the quality of the lowpass sub-band by 0.63 and 0.43 dB on average for our tested dynamic CT and MR volumes at the cost of an increase of the rate by 2.4% and 1.2% on average.
Convexity characterization of virtual view reconstruction error in multi-view imaging (2017)

Virtual view synthesis is a key component of multi-view imaging systems that enable visual immersion environments for emerging applications, e.g., virtual reality and 360-degree video. Using a small collection of captured reference view-points, this technique reconstructs any view of a remote scene of interest navigated by a user, to enhance the perceived immersion experience. We carry out a convexity characterization analysis of the virtual view reconstruction error that is caused by compression of the captured multi-view content. This error is expressed as a function of the virtual viewpoint coordinate relative to the captured reference viewpoints. We derive fundamental insights about the nature of this dependency and formulate a prediction framework that is able to accurately predict the specific dependency shape, convex or concave, for given reference views, multi-view content and compression settings. We are able to integrate our analysis into a proof-of-concept coding framework and demonstrate considerable benefits over a baseline approach.
Categorical representation and recognition of oscillatory motion patterns (2002)

Many communicative behaviors in the animal kingdom consist of performing and recognizing specialized patterns of oscillatory motion. Here we present an approach to the representation and recognition of these oscillatory motions based on the categorical organization of a simple sinusoidal model having very specific and limited parameter values. This characterization is used to specify the types and layout of computation for recognizing the patterns. Results of the method are demonstrated with real oscillatory motions showing the viability of a structured categorical framework.
Genotoxin-induced transcriptional repression regulates selective protein aggregation (2017)

Abstract Upon genotoxic stress, dynamic relocalization events control DNA repair, and alterations of the transcriptome and proteome enabling stress recovery. How these events may influence one another is only partly known. Beginning with a cytological screen for genome maintenance proteins that move under stress, we find that, upon alkylation stress, the splicing factor Hsh155 localizes to both intranuclear and cytoplasmic protein quality control aggregates. Under stress, an ordered sequestration of Hsh155 occurs at nuclear and then cytoplasmic aggregates in a manner that is regulated by molecular chaperones. This dynamic behavior is preceded by a decrease in splicing efficiency. While DNA replication stress signaling is not required for Hsh155 sequestration, Hsh155 aggregation is cell cycle and TOR pathway dependent. Indeed, loss of a TORC1 regulated ribosomal protein gene transcription factor Sfp1 allows general aggregate formation but prevents Hsh155 recruitment. Together, our analyses suggest a model in which some proteins evicted from chromatin undergoing transcriptional remodeling during stress are targeted to protein quality control sites.
Exploiting Structural Duplication for Lifetime Reliability Enhancement (2005)

Increased power densities (and resultant temperatures) and other effects of device scaling are predicted to cause significant lifetime reliability problems in the near future. In this paper, we study two techniques that leverage microarchitectural structural redundancy for lifetime reliability enhancement. First, in structural duplication (SD), redundant microarchitectural structures are added to the processor and designated as spares. Spare structures can be turned on when the original structure fails, increasing the processorýs lifetime. Second, graceful performance degradation (GPD) is a technique which exploits existing microarchitectural redundancy for reliability. Redundant structures that fail are shut down while still maintaining functionality, thereby increasing the processorýs lifetime, but at a lower performance. Our analysis shows that exploiting structural redundancy can provide significant reliability benefits, and we present guidelines for efficient usage of these techniques by identifying situations where each is more beneficial. We show that GPD is the superior technique when only limited performance or cost resources can be sacrificed for reliability. Specifically, on average for our systems and applications,GPD increased processor reliability to 1.42 times the base value for less than a 5% loss in performance. On the other hand, for systems where reliability is more important than performance or cost, SD is more beneficial. SD increases reliability to 3.17 times the base value for 2.25 times the base cost, for our applications. Finally, a combination of the two techniques (SD+GPD) provides the highest reliability benefit.
3D Investigations of Plasma Erosion Craters using FIB/SEM Dual-Beam Techniques (2006)

Abstract Plasma erosion craters caused by electrical discharges on the surface of materials are important features of the erosion processes resulting in the degradation of electrodes. In the present work, electrical discharges were produced on a bi-metallic Ni/Cu multilayered surface. By means of Dual Beam techniques, coupling a focused ion beam (FIB) and a scanning electron microscope (SEM), not only the surface but also the sub-surface structure of the craters were investigated. Using the combination of SEM, FIB and STEM-EDX, a complete three-dimensional investigation of the craters were carried out. The analysis of the microstructure modifications as a function of depth enabled to determine the field of interaction between the plasma and the material.
Reliability assessment of high temperature electronics and packaging technologies for Venus mission (2008)

In this paper, the potentials of the current state-of-the-art electronics and packaging technologies for Venus missions is evaluated and intend to address the survivability and reliability of the selected technologies and develop design-for-reliability guidelines for mission integration.
Diverse homeostatic and immunomodulatory roles of immune cells in the developing mouse lung at single cell resolution (2020)

At birth, the lungs rapidly transition from a pathogen-free, hypoxic environment to a pathogen-rich, rhythmically distended air-liquid interface. Although many studies have focused on the adult lung, the perinatal lung remains unexplored. Here, we present an atlas of the murine lung immune compartment during early postnatal development. We show that the late embryonic lung is dominated by specialized proliferative macrophages with a surprising physical interaction with the developing vasculature. These macrophages disappear after birth and are replaced by a dynamic mixture of macrophage subtypes, dendritic cells, granulocytes, and lymphocytes. Detailed characterization of macrophage diversity revealed an orchestration of distinct subpopulations across postnatal development to fill context-specific functions in tissue remodeling, angiogenesis, and immunity. These data both broaden the putative roles for immune cells in the developing lung and provide a framework for understanding how external insults alter immune cell phenotype during a period of rapid lung growth and heightened vulnerability.