gebhart/patrepeval huggingface dataset:
LLS (2004)

Coping with mobility and dynamism is one of the biggest challenges in ad hoc networks. An essential requirement for such networks is a service that can establish communication sessions between mobile nodes whose location is unknown. A location service for ad hoc networks is a distributed algorithm that allows any source node s to know the location of any destination node t, simply by knowing t's network identifier.A location service has a locality aware lookup algorithm if the cost of locating destination t from source s is proportional to the cost of the minimal cost path between s and t. A location service has a locality aware publish algorithm if the cost of updating the location service due to a node moving from x to y is proportional to the distance between x and y.In this paper we present LLS, the first location service for the Unit Disk Graph model whose lookup and publish algorithms have worst case locality guarantees and average case locality awareness efficiency for any source destination pair.
A New Photoannulation Reaction of 2-Aryl-3-alkoxy-1,4-naphthquinones. Synthesis of Dimethylnaphthgeranine E (1997)

ADVERTISEMENT RETURN TO ISSUECommunicationNEXTA New Photoannulation Reaction of 2-Aryl-3-alkoxy-1,4-naphthquinones. Synthesis of Dimethylnaphthgeranine EThomas J. Onofrey, Dario Gomez, Michael Winters, and Harold W. MooreView Author Information Department of Chemistry, University of California at Irvine, Irvine, California 92697Cite this: J. Org. Chem. 1997, 62, 17, 5658–5659Publication Date (Web):August 22, 1997Publication History Received28 February 1997Published online22 August 1997Published inissue 1 August 1997https://pubs.acs.org/doi/10.1021/jo970385chttps://doi.org/10.1021/jo970385crapid-communicationACS PublicationsCopyright © 1997 American Chemical SocietyRequest reuse permissionsArticle Views565Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Carbonyls,Oxidation,Photodissociation,Quinones,Substitution reactions Get e-Alerts
Multi-Core Programming with CUDA and OpenCL (2011)

MULTI-CORE PROGRAMMING WITH CUDA AND OPENCL covers multi-core GPU programming with some emphasis on CPU vs GPU hardware, with benchmark/performance tests to show improvements from purely a CPU approach to a GPU approach to processing data using several different libraries includiung CUDA, OpenCL, and DirectCompute. Topics include differences and capabilities of hardware architectures, parallel API's and algorithm design for parallel machines. Emphasis will be on practical, applied use of these multi-core GPU libraries. In order for these new architectures to be utilized, programmers must educate themselves on the advantages, limitations, and algorithm design methods for parallel computing platforms.This is a very important but challenging subject that encompasses multi-threading, symmetric multi-processing (SMP), and parallel processing on the CPU side, and massively parallel processing on the GPU side. The book includes end-of-chapter exercises, discussions, and quizzes.
The effect of external fixation stiffness on early healing of transverse osteotomies (1989)

The effect of bending stiffness of external fixators on the early healing of transverse tibial osteotomies was studied in a canine model to determine whether there is a particular range of fixation stiffness where healing is poor. Five unilateral fixators with different stiffnesses were developed and employed along with a dynamic compression plate to fix experimental osteotomies of dog tibias and the contralateral intact tibias served as controls. The six experimental fixation devices were: plate (P), stainless steel sidebar fixator (SS), stiff aluminum sidebar fixator (SA), intermediate aluminum sidebar fixator (IA), flexible aluminum sidebar fixator (FA), and Delrin sidebar fixator (D). Compared with human tibial fixation methods, the fixators ranged from a rigidity greater than a plate on a human tibia to a flexibility similar to a plaster cast on a human lower leg. Sixty-four adult male mongrel dogs (29 +/- 3 kg) underwent surgery and 52 completed the 9-week study, leaving 7 to 10 dogs in each experimental group (P = 8, SS = 7, SA = 9, IA = 9, FA = 10, D = 9). After the 9-week survival period the experimental tibias were radiographed and callus area was digitized. Both the experimental and control tibias were then tested to failure in four-point bending, and failure moment, stiffness, and energy to failure were determined. Of the 52 osteotomies, only four developed nonunions: 3 of 10 in the FA group and 1 of 7 in the SS group. Using analysis of variance, no statistical differences were detected in failure force, stiffness, or energy to failure as a function of fixator groups.(ABSTRACT TRUNCATED AT 250 WORDS)
An Energy Conserving Oceanographic Profiler For Use Under Mobile Ice Cover; ICYCLER (2004)

ICYCLER is a moored oceanographic profiler designed to measure surface layer water properties under mobile ice cover. The profiler can provide daily 50 meter salinity-temperature-chlorophyll profiles for a full year. Data are collected during each profiling ascent with an instrumented float that avoids ice impact using an onboard echo sounder. Once measurements are acquired, the sensors are hauled back down to an ice-free depth. An efficient energy-conserving mechanical design minimizes power requirements to allow for a logistically manageable and hydrodynamically efficient package. An ICYCLER prototype was successfully used the Canadian Arctic Archipelago for a year-long deployment and a second re-designed ICYCLER is being tested for Arctic deployment in the summer of 2004.
A Single Reactive Noncanonical Amino Acid Is Able to Dramatically Stabilize Protein Structure (2019)

A p-isothiocyanate phenylalanine mutant of the homodimeric protein homoserine o-succinyltransferase (MetA) was isolated in a temperature dependent selection from a library of metA mutants containing noncanonical amino acids. This mutant protein has a dramatic increase of 24 °C in thermal stability compared to the wild type protein. Peptide mapping experiments revealed that the isothiocyanate group forms a thiourea cross-link to the N terminal proline of the other monomer, despite the two positions being >30 Å apart in the X-ray crystal structure of the wild type protein. These results show that an expanded set of building blocks beyond the canonical 20 amino acids can lead to significant changes in the properties of proteins.
Clinical Diagnostic Study of a Novel Injection Molded Swab for SARS-Cov-2 Testing (2021)

The gold standard for COVID-19 diagnosis is currently a real-time reverse transcriptase polymerase chain reaction (RT-PCR) to detect SARS-CoV-2. This is most commonly performed on respiratory secretions obtained via a nasopharyngeal swab. Due to supply chain limitations and high demand worldwide because of the COVID-19 pandemic, access to commercial nasopharyngeal swabs has not been assured. 3D printing methods have been used to meet the shortfall. For longer-term considerations, 3D printing may not compare well with injection molding as a production method due to the challenging scalability and greater production costs of 3D printing. To secure sufficient nasopharyngeal swab availability for our national healthcare system, we designed a novel injection molded nasopharyngeal swab (the IM2 swab). We performed a clinical diagnostic study comparing the IM2 swab to the Copan FLOQSwab. Forty patients with a known diagnosis of COVID-19 and 10 healthy controls were recruited. Paired nasopharyngeal swabs were obtained from the same nostril of each participant and tested for SARS-CoV-2 by RT-PCR. When compared to the Copan FLOQswab, results from the IM2 swab displayed excellent overall agreement and positive percent agreement of 96.0% and 94.9%, respectively. There was no significant difference in mean RT-PCR cycle threshold values for the ORF1ab (28.05 vs. 28.03, p = 0.97) and E-gene (29.72 vs. 29.37, p = 0.64) targets, respectively. We did not observe any significant adverse events and there was no significant difference in patient-reported pain. In summary, the IM2 nasopharyngeal swab is a clinically safe, highly accurate option to commercial nasopharyngeal swabs.
Monoamine Oxidase-Catalyzed Oxidative Rearrangement of trans,trans-1-(Aminomethyl)-2-methoxy-3-phenylcyclopropane (1996)

trans,trans-1-(Aminomethyl)-2-methoxy-3-phenylcyclopropane (3) was synthesized in three steps from (Z)-beta-methoxystyrene and ethyl diazoacetate. Compound 3 was shown to be a substrate and inactivator of mitochondrial beef liver monoamine oxidase (MAO) with a partition ratio of 1428. MAO-catalyzed oxidation of 3 produces one major metabolite, isolated and identified by GCOSY, GHMQC, and GHMBC NMR techniques to be trans,trans-2-methoxy-3-phenyl-1-N-[(3-phenyl-N-pyrrolyl)methyl]cyclopropane (7). A mechanism, supported by a model reaction, is proposed for the formation of this metabolite.
Dysregulation of Galectin-3. Implications for Hermansky-Pudlak Syndrome Pulmonary Fibrosis (2013)

The etiology of Hermansky-Pudlak syndrome (HPS) pulmonary fibrosis (HPSPF), a progressive interstitial lung disease with high mortality, is unknown. Galectin-3 is a β-galactoside-binding lectin with profibrotic effects. The objective of this study was to investigate the involvement of galectin-3 in HPSPF. Galectin-3 was measured by ELISA, immunohistochemistry, and immunoblotting in human specimens from subjects with HPS and control subjects. Mechanisms of galectin-3 accumulation were studied by quantitative RT-PCR, Northern blot analysis, membrane biotinylation assays, and rescue of HPS1-deficient cells by transfection. Bronchoalveolar lavage galectin-3 concentrations were significantly higher in HPSPF compared with idiopathic pulmonary fibrosis or that from normal volunteers, and correlated with disease severity. Galectin-3 immunostaining was increased in HPSPF compared with idiopathic pulmonary fibrosis or normal lung tissue. Fibroblasts from subjects with HPS subtypes associated with pulmonary fibrosis had increased galectin-3 protein expression compared with cells from nonfibrotic HPS subtypes. Galectin-3 protein accumulation was associated with reduced Galectin-3 mRNA, normal Mucin 1 levels, and up-regulated microRNA-322 in HPSPF cells. Membrane biotinylation assays showed reduced galectin-3 and normal Mucin 1 expression at the plasma membrane in HPSPF cells compared with control cells, which suggests that galectin-3 is mistrafficked in these cells. Reconstitution of HPS1 cDNA into HPS1-deficient cells normalized galectin-3 protein and mRNA levels, as well as corrected galectin-3 trafficking to the membrane. Intracellular galectin-3 levels are regulated by HPS1 protein. Abnormal accumulation of galectin-3 may contribute to the pathogenesis of HPSPF.
Bandwidth-optimal single-tunable-element matching network for antenna tuning in mobile handsets (2011)

This paper presents a single-tunable-element matching network that is optimized for the GSM850 and GSM900 bands. It is designed to counteract the detuning of mobile handset antennas by optimizing the transducer gain of the network. A simple model that emulates the antenna detuning effects based on extensive measurements from the literature is first presented. Based on this model it is shown that a matching network with a single tunable element suffices to cover the two aforementioned bands. Implementations for a planar inverted-F antenna (PIFA) as well as a proof-of-concept for the iPhone 4™ antenna are presented. The measured results, in good agreement with the modeled data, indicate that transducer gain improvements of up to 3.5 dB (53%) and 5.6 dB (57%) can be obtained for the PIFA and iPhone 4™ implementations, respectively.
Application of Kolmogorov complexity in anomaly detection (2010)

Kolmogorov complexity is the basis of algorithmic randomness theory. It quantifies the amount of information of individual object, which is measured by the size of its smallest algorithmic description. The concept of Kolmogorov complexity is used in many applications like spam filtering, data compression, information assurance etc. In this paper, we present the application of Kolmogorov complexity in network security field, particularly for anomaly detection. In order to accomplish that, it is assumed that most of the network attacks change the structure of the traffic. This enforces anomaly and hence subsequent intrusion can be detected if the structure or signature of the traffic flow is investigated. From this notion, we propose a signature based anomaly detection scheme. We show through simulation results that with the help of Kolmogorov complexity, we can detect traffic pattern abnormality in a simplistic way. This detection and quantification of traffic pattern eventually lead to anomaly detection.
[Detection of human papillomavirus DNA by molecular hybridization in tube: interest in cervical neoplasia]. (1999)

The presence of human papillomavirus (HPV) DNA in 79 cervical specimens obtained from 70 patients was studied by using a molecular hybridization technique performed in tube. The results were compared to those of the cytological and histological studies. The molecular hybridization technique in tube (Hybrid Capture I) detects two groups of HPV types. One group is highly associated with the development of cancer (types 16, 18, 31, 33, 35, 45, 51, 52, 56) whereas the second group (types 6, 11, 42, 43, 44) is not. Among 42 patients with cervical lesions before any treatment, high risk DNA of HPV was found in 50% of those with low grade cytology and 90% with high grade cytology. In total, 32 out of the 42 patients (76%) who presented histological lesions, were actually infected by HPV. Samples were obtained before and after treatment from 9 patients. Seven out of 9 presented high grade cervical intraepithelial neoplasia (CIN) and 2 other patients had low grade CIN. HPV DNA was not detected in any of the patients after treatment. Detection of HPV DNA by molecular hybridization in tube is simple, sensitive, standardized, inexpensive and is well adapted to screening programs. It can be used in complement of the cytological diagnosis, in the surveillance of equivocal cytological abnormalities, and in the follow-up of treated patients.
Lymphoid Cell-Glioma Cell Interaction Enhances Cell Coat Production by Human Gliomas: Novel Suppressor Mechanism (1983)

Certain human glioma lines produce mucopolysaccharide coats that impair the generation of cytolytic lymphocytes in response to these lines in vitro. Coat production is substantially enhanced by the interaction of glioma cells with a macromolecular factor released by human peripheral blood mononuclear cells in culture. This interaction thus constitutes an unusual mechanism by which inflammatory cells may nonspecifically suppress the cellular immune response to at least one class of solid tumors in humans.
Delay Tracking in Spaceborne GNSS-R Ocean Altimetry (2012)

Tracking, in radar altimetry, is the positioning of the waveforms in the correlation window. This letter presents a tracking strategy in spaceborne altimetry using global navigation satellite system reflectometry. First, the tracking procedure is illustrated, and the tracking parameters are discussed one by one: the determination of the correlation window, the accuracy of specular delay guess, and the tracking-refresh period. Based on the results, the proposed European Space Agency Passive Reflectometry and Interferometry System In-Orbit Demonstrator tracking case study is examined.
SINE Compounds Demonstrate Efficacy in a Preclinical Model of Multiple Sclerosis and an In Vitro Screening of Viral Agents of Coinfection (P1.405) (2017)

This study evaluated the neuroprotective and anti-inflammatory properties of Selective Inhibitor of Nuclear Export (SINE) compounds in a murine model of multiple sclerosis (MS) as well as their antiviral properties against common agents of coinfection and progressive multifocal leukoencephalopathy (PML).
Microstructure And Mechanical Properties of Friction Stir Welded High-Strength Steel For Drilling Pipe (2011)

Friction stir welding (FSW) is an attractive method in welding of steels due to high energy efficiency, few solidification related defects, and reduction of distortion. In this study, microstructures and mechanical properties of FS welded P110 API-grade steel were examined. Microstructure of the stir zone (SZ) mainly consisted of the quenched martensite with low fraction of bainite, which led to very high hardness. The decrease in rotational speed could significantly reduce fraction of quenched martensite in the SZ, resulting in roughly the same hardness of the base material.
Nanofibrillar scaffolds induce preferential activation of Rho GTPases in cerebral cortical astrocytes (2012)

Cerebral cortical astrocyte responses to polyamide nanofibrillar scaffolds versus poly-L-lysine (PLL)-functionalized planar glass, unfunctionalized planar Aclar coverslips, and PLL-functionalized planar Aclar surfaces were investigated by atomic force microscopy and immunocytochemistry. The physical properties of the cell culture environments were evaluated using contact angle and surface roughness measurements and compared. Astrocyte morphological responses, including filopodia, lamellipodia, and stress fiber formation, and stellation were imaged using atomic force microscopy and phalloidin staining for F-actin. Activation of the corresponding Rho GTPase regulators was investigated using immunolabeling with Cdc42, Rac1, and RhoA. Astrocytes cultured on the nanofibrillar scaffolds showed a unique response that included stellation, cell-cell interactions by stellate processes, and evidence of depression of RhoA. The results support the hypothesis that the extracellular environment can trigger preferential activation of members of the Rho GTPase family, with demonstrable morphological consequences for cerebral cortical astrocytes.
PCI-based multi-processor system for immersive videoconference terminals (2003)

This paper introduces newly developed hardware components and configuration aspects for a complex video-processing system based on PCI architectures. Originally designed for an immersive videoconference system, the modular, scalable and cost efficient multi-processor structure can also be applied to other demanding signal processing applications. Announcing the videoconference system, we derive and explain the structure of a PCI subsystem based on four TriMedia processors and an open interface architecture. First application results of the introduced components are presented regarding PCI compatibility, processing power as well as the system architecture for an immersive videoconference system.
Effect of acceptor concentration on the bulk electrical conduction in acceptor (Mg)-doped BaTiO3 (2010)

Bulk electrical conductivity of acceptor (Mg)-doped BaTiO3 ceramics were evaluated via an impedance spectroscopy analysis for materials with Mg concentrations up to 0.6 mol % and over a temperature range of 120–540 °C. At high temperatures beyond 320 °C, the activation energies of the bulk electrical conduction (Eσ) slightly decreased from 1.2 to ∼1.0 eV with an increase in the Mg concentration. However, in the low temperature range below 320 °C, there is a continuous decreased from 1.2 eV and then this saturated to ∼0.4 eV with the increase in Mg concentration. The calculated bulk conductivities based on a defect chemistry model explains conductivity for temperatures above 320 °C. The model demonstrates a predominant electronic conduction in the low concentration range below 0.1 mol % Mg and mixed conduction with ionic and electronic carriers in the intermediate and in high acceptor concentration range of 0.2–0.6 mol % Mg. However, the decrease in Eσ with the increase in Mg concentration in the low temperature range could not be explained by the defect chemical model. Such deviation however could be explained by a transition to hopping conduction between ionized acceptor (MgTi″) and neutral or hole-trapped acceptor (MgTi×) with the increase in Mg concentration in the low temperature range.
Using wearable devices for assessing the impacts of hair exposome in Brazil (2019)

Previous studies have shown that physicochemical properties of hair can be impacted by internal and environmental exposures ranging from chemical stressors to weather. Besides the effects on hair, these exposures, termed "exposome", can act on specific organs including skin, as a synergistic damaging effect of UV exposure and pollution on human surfaces. The combination of several environmental factors such as sun exposure, temperature, relative humidity, air pollution and photo-oxidation caused by ground level ozone impacts hair properties such as melanin oxidation, protein content, surface quality and structural components. Therefore, exposome studies can reveal new hypotheses on how epithelia and hair could be affected by daily life environment and routine. The aim of this study was to evaluate the impact of several environmental aggressors on human surfaces, using portable and wearable devices for monitoring exposome. To better understand the underlying mechanisms associated with environmental factors, two subjects wore multiple sensors to capture the meteorological conditions biking through urban areas in summer and winter. Temperature, humidity, UV radiation and ozone concentration were recorded and hair swatches of different types, including natural, bleached/colored, colored and gray, were exposed on the helmets. Silicon wristbands were used on skin to identify main chemical aggressors. After exposure, hair swatches were analyzed by surface microscopy analysis, oxidation markers and more than 1,500 chemicals were evaluated on the bracelets. Correlated with GPS and monitoring data, all these results provide insights on how environmental stressors affect the quality of different hair types and body surface according to exposure routine. Our results suggest extreme climate conditions associated with hair damage and photo-oxidative marker linked to the environmental aggressors. Polycyclic aromatic hydrocarbons (PAH) indicate possible causes of hair damages. This is the first meteorotropic study of its kind, combining environmental aggressors related to hair damage, opening new research hypothesis further studies on exposome.
A GPU based Parallel Hierarchical Fuzzy ART clustering (2011)

Hierarchical clustering is an important and powerful but computationally extensive operation. Its complexity motivates the exploration of highly parallel approaches such as Adaptive Resonance Theory (ART). Although ART has been implemented on GPU processors, this paper presents the first hierarchical ART GPU implementation we are aware of. Each ART layer is distributed in the GPU's multiprocessors and is trained simultaneously. The experimental results show that for deep trees, the GPU's performance advantage is significant.