gebhart/patrepeval huggingface dataset:
Platelet Adhesion to Collagen Under Flow Causes Dissociation of a Phosphoprotein Complex of Heat-Shock Proteins and Protein Phosphatase 1 (1997)

Phosphorylation/dephosphorylation events in human blood platelets were investigated during their adhesion to collagen under flow conditions. Using 32P-labeled platelets and one-dimensional gel electrophoresis, we found that adhesion to collagen mediated primarily by the α2β1 integrin resulted in a strong dephosphorylation of several protein bands. Neither adhesion to polylysine nor thrombin-induced aggregation caused similar protein dephosphorylation. In addition, treatment with okadaic acid (OA), an inhibitor of serine/threonine protein phosphatases type 1 (PP1) and 2A (PP2A), caused significant inhibition of adhesion, suggesting that adhesion is regulated by OA-sensitive phosphatases. Recent studies indicate that phosphatases may be associated with the heat-shock proteins. Immunoprecipitations with antibodies against either the heat-shock cognate protein 70 (hsc70) or heat-shock protein 90 (hsp90) showed the presence of a phosphoprotein complex in 32P-labeled, resting human platelets. Antibody probing of this complex detected hsc70, hsp90, two isoforms of the catalytic subunit of PP1, PP1Cα and PP1Cδ, as well as the M regulatory subunit of PP1 (PP1M). OA, at concentrations that markedly blocked platelet adhesion to collagen, caused hyperphosphorylation of the hsc70 complex. In platelets adhering to collagen, hsc70 was completely dephosphorylated and hsp90, PP1α, and PP1M were dissociated from the complex, suggesting involvement of heat-shock proteins and protein phosphatases in platelet adhesion.
Figure S3 from Cobomarsen, an Oligonucleotide Inhibitor of miR-155, Slows DLBCL Tumor Cell Growth <i>In Vitro</i> and <i>In Vivo</i> (2023)

&lt;p&gt;Supplementary figure S3&lt;/p&gt;
Photoinduced Electron Transfer from a Tetrathiafulvalene-Calix[4]pyrrole to a Porphyrin Carboxylate within a Supramolecular Ensemble (2014)

A supramolecular assembly is formed upon mixing millimolar concentrations of a tetrakis-tetrathiafulvalene calix[4]pyrrole (TTF-C4P) and a porphyrin tetraethylammonium carboxylate salt in benzonitrile (PhCN). The TTF-C4P binds to the carboxylate moiety of the porphyrin with a 1:1 stoichiometry and a binding constant of 6.3 × 104 M–1 in this solvent at 298 K. Laser photoexcitation of the supramolecular complex results in formation of the triplet charge-separated (CS) state composed of a radical cation of the TTF-C4P receptor and the radical anion of the porphyrin carboxylate. These processes and the resulting states were characterized by means of transient absorption and electron spin resonance (ESR) spectroscopies. The rate constants corresponding to the forward and backward intramolecular electron-transfer (ET) processes were determined to be 2.1 × 104 and 3.6 × 102 s–1, respectively. The rate constants of intermolecular forward and backward electron transfer were also determined to be 4.4 × 108 and 9.8 × 108 M–1 s–1, respectively. The electronic coupling constant (V), 1.2 × 10–2 cm–1, and the reorganization energy (λ), 0.76 eV, for back electron transfer were evaluated from the temperature dependence of the rate constants of intramolecular electron transfer. The small V value indicates little spin-forbidden interaction between the highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) and substantiates the long-lived CS lifetime. These results were corroborated by density function theory (DFT) calculations, which provided support for the conclusion that the HOMO and LUMO, located on a TTF moiety of the TTF-C4P and the porphyrin core, respectively, have little interaction though space.
A multiscale analysis of ductile steel grades damage and fracture mechanisms (2009)

International audience
Fast 3D Shape Recovery from Shadows Projected on Arbitrary Curved Surfaces (2010)

The shadow based 3D surface reconstruction methods usually assume that shadows are projected on planar surfaces. However, shadows are often projected on curved surfaces in the real scene. Recently, the shadow graph has been proposed for representing shadow information efficiently, and for recovering 3D shapes from shadows projected on curved surfaces. Unfortunately, the method requires a large computational cost and is weak to the image intensity noises. In this paper, we introduce 1D shadow graphs which can represent shadow information quite efficiently, and can be used for recovering 3D shapes with much smaller computational costs than before. We also extend our method, so that we can recover 3D shape quite accurately by using shading information as well as shadow information. The proposed method is tested by using the real and synthetic images.
Reductive elimination of HH, HCH3, and CH3CH3 from bis(phosphine)platinum(II), -palladium(II), and -nickel(II) complexes: a theoretical study using the SCF-X.alpha.-SW method (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReductive elimination of HH, HCH3, and CH3CH3 from bis(phosphine)platinum(II), -palladium(II), and -nickel(II) complexes: a theoretical study using the SCF-X.alpha.-SW methodAnna C. Balazs, Keith H. Johnson, and George M. WhitesidesCite this: Inorg. Chem. 1982, 21, 6, 2162–2174Publication Date (Print):June 1, 1982Publication History Published online1 May 2002Published inissue 1 June 1982https://pubs.acs.org/doi/10.1021/ic00136a007https://doi.org/10.1021/ic00136a007research-articleACS PublicationsRequest reuse permissionsArticle Views173Altmetric-Citations37LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Transductive Learning for Abstractive News Summarization (2021)

Pre-trained and fine-tuned news summarizers are expected to generalize to news articles unseen in the fine-tuning (training) phase. However, these articles often contain specifics, such as new events and people, a summarizer could not learn about in training. This applies to scenarios such as a news publisher training a summarizer on dated news and summarizing incoming recent news. In this work, we explore the first application of transductive learning to summarization where we further fine-tune models on test set inputs. Specifically, we construct pseudo summaries from salient article sentences and input randomly masked articles. Moreover, this approach is also beneficial in the fine-tuning phase, where we jointly predict extractive pseudo references and abstractive gold summaries in the training set. We show that our approach yields state-of-the-art results on CNN/DM and NYT datasets, improving ROUGE-L by 1.05 and 0.74, respectively. Importantly, our approach does not require any changes of the original architecture. Moreover, we show the benefits of transduction from dated to more recent CNN news. Finally, through human and automatic evaluation, we demonstrate improvements in summary abstractiveness and coherence.
Spoof surface plasmon enhanced reflection in THz parallel plate waveguides (2012)

Back reflection from the end of a parallel-plate metal waveguide (PPWG) can be enhanced up to 99% at a selected frequency by patterning on the output facet. The enhanced reflectivity depends on the incident angle in the PPWG and shows a lateral shift comparing to mirror reflection, which is an analogue of the Goos-Hanchen effect in this context. We show how this concept can be used as the basis for designing resonant waveguide structures.
Differentiating coupling factor and VA transfer of IPT systems using bipolar pad primaries (2016)

Coupling factor is a important design parameter in inductive power transfer (IPT) systems as it determines the amount of VA effort required from the primary pad to deliver the necessary VA to the secondary pad. As IPT systems involve more complex magnetic systems such as multi-coil primary pads (whose currents can have an amplitude and phase difference), the effective coupling factor becomes more difficult to describe and validate. Typically, an equivalent T-model is used for two coupled single coil pads; however, this is insufficient for multi-coil primaries such as a bi-polar pad (BPP). As such, this paper introduces an equation which is able to describe the effective coupling factor of an IPT system with a multi-coil primary and a single coil secondary while considering the reflected impedances between the coils.
Reducing Energy Losses from Automotive Engine Lubricants by Thermal Isolation of the Engine Mass (2014)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;The thermal efficiency of an internal combustion engine at steady state temperatures is typically in the region of 25-35%[&lt;span class="xref"&gt;1&lt;/span&gt;]. In a cold start situation, this reduces to be between 10% and 20% [&lt;span class="xref"&gt;2&lt;/span&gt;]. A significant contributor to the reduced efficiency is poor performance by the engine lubricant. Sub optimal viscosity resulting from cold temperatures leads to poor lubrication and a subsequent increase in friction and fuel consumption.&lt;/div&gt;&lt;div class="htmlview paragraph"&gt;Typically, the engine lubricant takes approximately twenty minutes [&lt;span class="xref"&gt;3&lt;/span&gt;] to reach steady state temperatures. Therefore, if the lubricant can reach its steady state operating temperature sooner, the engine's thermal efficiency will be improved.&lt;/div&gt;&lt;div class="htmlview paragraph"&gt;It is hypothesised that, by decoupling the lubricant from the thermal mass of the surrounding engine architecture, it is possible to reduce the thermal energy loss from the lubricant to the surrounding metal structure in the initial stages of warm-up.&lt;/div&gt;&lt;div class="htmlview paragraph"&gt;Using a bespoke oil flow rig described in the methodology section of this paper, it has been demonstrated that the addition of a 2 mm thick nylon tube, increases the maximum temperature differential between the lubricant and surrounding metal by 145% and reduces the energy losses from the gallery by 50%. This results from the addition of both a high thermal resistance material and a contact resistance between the polymer tube and metal.&lt;/div&gt;&lt;div class="htmlview paragraph"&gt;The insulating performance of nylon has been closely matched by utilising a specially designed aluminium insert with a 0.5 mm air gap. The increased contact resistance of such an insert has been shown to increase the temperature differential by 107% and reduce energy losses by 40%.&lt;/div&gt;&lt;/div&gt;
Generation of High Current Densities by Pure Cultures of Anode-Respiring Geoalkalibacter spp. under Alkaline and Saline Conditions in Microbial Electrochemical Cells (2013)

This study establishes the highest current densities ever achieved by pure cultures of anode-respiring bacteria (ARB) under alkaline and saline conditions in microbial electrochemical cells (MXCs) and provides the first electrochemical characterization of the genus Geoalkalibacter. Production of high current densities among the Geobacteraceae is no longer exclusive to Geobacter sulfurreducens, suggesting greater versatility for this family in fundamental and applied microbial electrochemical cell (MXC) research than previously considered. Additionally, this work raises the possibility that different members of the Geobacteraceae have conserved molecular mechanisms governing respiratory extracellular electron transfer to electrodes. Thus, the capacity for high current generation may exist in other uncultivated members of this family. Advancement of MXC technology for practical uses must rely on an expanded suite of ARB capable of using different electron donors and producing high current densities under various conditions. Geoalkalibacter spp. can potentially broaden the practical capabilities of MXCs to include energy generation and waste treatment under expanded ranges of salinity and pH.
A Study of Mesh-Fed Slot Film Cooling (2010)

This investigation demonstrates the potential improvement in adiabatic film effectiveness that can be achieved through the use of mesh-fed surface slot film cooling. Mesh, or in-wall network, cooling is composed of fairly compact arrays of pedestals sized to fit within the limited wall thickness of a turbine airfoil. When the coolant discharge from such a mesh is along a shallow ramp to the airfoil aerodynamic surface (i.e., like an angled film hole), the resulting film effectiveness from this combined geometry can be very high. The in-wall mesh network acts as the structural means for obtaining the slot geometry. In this study, flat plate warm wind tunnel testing has been conducted on two mesh-fed film geometries and compared against data for a row of axial round film holes, as well as a row of shaped diffuser film holes. The mesh-fed geometries are composed of pedestal arrays with height-to-diameter ratios of 0.2 exiting onto 20-deg inclines to the surface. The mesh slot exit film blowing ratios tested ranged from M=0.1 to M=0.7, while round and shaped film hole conditions covered 0.5 to 1.2. The mesh-fed film effectiveness results indicate a performance greater than that of shaped diffuser holes, but less than that of a more idealistic two-dimensional slot film geometry. The mesh-fed film effectiveness was as much as 25% higher than that for shaped holes in the near-hole region of x/Ms&lt;50, and up to 100% greater in the downstream region of x/Ms&gt;50.
A Zeolite Family Nonjointly Built from the 1,3‐Stellated Cubic Building Unit (2017)

Abstract From a technological point of view, the synthesis of new high‐silica zeolites is of prime importance owing to their high potential as industrial catalysts and catalyst supports. Two such materials have been synthesized which are made up of the 1,3‐stellated cubic unit (hexahedral ([4 2 5 4 ]) bre unit) as a secondary building unit, with the aid of existing imidazolium‐based structure‐directing agents under “excess fluoride” conditions. One of them, denoted PST‐21, is the first aluminosilicate zeolite consisting of 9‐ring apertures solely; it displays exceptional activity towards steering the skeletal isomerization of 1‐butene to isobutene and bridges the gap between small‐ and medium‐pore structures. A series of hypothetical structures are also described that are nonjointly built from the bre unit; all of these structures are chemically feasible and will thus be helpful in designing the synthesis of novel zeolites containing 9‐ring and/or 10‐ring channels.
Fabrication and Characterization of Porous Microneedles for Enhanced Fluid Injection and Suction: A Two‐Photon Polymerization Approach (2023)

Porous microneedles (MNs) offer broad advantages such as fluid capture and filtration. Compared to hollow MNs, fluid injection through porous MNs causes a broader diffusion spread. Herein, three MN designs with a constant pore size and controlled pore locations are fabricated and compared, using two‐photon polymerization (2PP), by examining factors such as diffusion spread, mixing capabilities, and mechanical resilience. Results show that the porous MN can cover 16 times the injection area than that of the hollow MN. Porous MNs also show good mixing capabilities with two fluids. Mechanical compression results reveal that one porous MN can withstand a load of 0.6 N.
[POSTER] Noh as Intermedia: Interactive Multi-Scale, Multimedia Analyses of Full-Length Noh Theater Performances (2020)

This project uses interactive multimedia web technologies to explore and illustrate how Japanese Noh theater derives much of its expressive power from intermedia: drawing on relations between literature, music, and staging for cumulative impact. The project site builds a multi-scale "thick" analysis around two exemplary and contrasting Noh plays. The levels of analysis presented on the site range from high-level essays to mid-scale catalogs of media components (dramatic forms, modes of speech and singing, melodic and rhythmic patterns, movement, other aspects of stagecraft) to an innovative annotated video playback environment in which verbal, musical, and theatrical elements are visualized on a score that is synchronized to the video at sub-second granularity. The finished site engages with the tension between facilitating in-depth annotation and exploration of a single genre and providing a general-use digital platform for performing arts analysis.
Titelei/Inhaltsverzeichnis (2019)

Mit Musik gemeinsam gegen das Trauma: Rhythmisches Musizieren in der Gruppe zielt als nonverbale traumapädagogische Intervention auf die Förderung und Steigerung der (Selbst-)Heilungsressourcen gewalterfahrener und traumatisierter Jugendlicher in der stationären Kinder- und Jugendhilfe.
Carlisle museum catalogue (1894)

Journal Article Carlisle museum catalogue Get access Robert Bateman Robert Bateman Search for other works by this author on: Oxford Academic Google Scholar Notes and Queries, Volume s8-V, Issue 109, 27 January 1894, Page 77, https://doi.org/10.1093/nq/s8-V.109.77i Published: 27 January 1894
Differentially flat mobile manipulators mounted with an under-actuated vertical arm (2010)

This paper discusses how mobile manipulators with an under-actuated vertical arm can be designed to be differentially flat. The property of differential flatness is achieved by appropriate inertia redistribution of the vertical arm and a wide range of under-actuation becomes possible. As a result of having the flatness property, the under-actuated mobile manipulators are capable of executing point-to-point maneuvers as mobile manipulators with a fully actuated arm would do. In addition, the trajectory planning and feedback controller design for point-to-point motions in state space is considerably simplified despite the under-actuation of the arm and nonholonomic constraints (from no-slip assumption) of the mobile base, which make the system more difficult to plan and control. These ideas are demonstrated through an illustrative example of a mobile manipulator consisting of an under-actuated vertical three-link arm and a two-wheeled differentially driven mobile base using differential flatness.
CD8+CD4− lymphocyte lines can harbor the AIDS virus in vitro. (1989)

A detailed definition of AIDS virus-specific T lymphocytes will require the generation and characterization of HIV-1-specific, cloned T cell populations. In our studies, we show that CD8+CD4- lymphocyte lines, derived from PBL of rhesus monkeys infected with simian immunodeficiency virus of macaques and humans infected with HIV-1, can harbor AIDS viruses. CD8+CD4- lymphocyte lines derived from infected individuals are shown to express AIDS virus-encoded proteins and generate reverse transcriptase activity. Infection of these CD8+CD4- lymphocytes is confirmed at the single cell level by the techniques of immunoelectronmicroscopy and two-color immunohistochemistry. This observation suggests that it may prove problematic to generate cloned, functional T lymphocyte populations from AIDS virus-infected individuals and raises the possibility that CD8+CD4- cells may serve as reservoirs for the AIDS viruses.
ChemInform Abstract: Asymmetric Synthesis of a Seven Carbon anti‐3,5‐Diol Building Block. A Polyacetate Derivative with Completely Resolved C2 Symmetry. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Cloning of a novel EGFR-related peptide: a putative negative regulator of EGFR (2001)

Although epidermal growth factor receptor (EGFR) plays a key role in regulating cell proliferation, differentiation, and transformation in many tissues, little is known about the factor(s) that may modulate its function. We have isolated a cDNA clone from the rat gastroduodenal mucosa whose full length revealed 1,958 bp that contained 227 bp of 5'-untranslated region (UTR) and an open-reading frame encoding 479 amino acids, followed by 290 bp of 3'-UTR. It showed ~85% nucleotide homology to the external domain of the rat EGFR. We refer to the product of the newly isolated cDNA as EGFR-related protein (ERRP). In Northern blot analysis with poly(A)(+) RNA from different rat tissues, ERRP cDNA hybridized to several mRNA transcripts with the strongest reaction noted with a transcript of approximately 2 kb. Maximal expression of the 2-kb mRNA transcript was observed in the small intestine, followed by colon, liver, gastric mucosa, and other tissues. Transfection of ERRP cDNA into a colon cancer cell line, HCT116, resulted in a marked reduction in proliferation in monolayer and colony formation in soft agar compared with the vector-transfected controls. In another colon cancer cell line, Caco-2, with a tetracycline-regulated promoter system, induction of ERRP expression in the absence of doxycycline was associated with a marked reduction in EGFR activation and proliferation. We conclude that the ERRP cDNA may represent a new member of the EGFR gene family and that ERRP plays a role in regulating cell proliferation by modulating the function of EGFR.
Novel InSb/photochemical native oxide interface (1988)

A novel interface to InSb based on photochemical native oxide (PNOX), which improves conventional ultraviolet (UV) enhanced deposition, is reported. Prior to the deposition of SiO2, an additional stage of growing a native oxide by exposing the semiconductor to N2O and Hg vapors at low pressure under UV illumination is introduced. Composition and electrical properties of the interface are discussed. Compositional analysis was performed by Auger electron spectroscopy. Electrical properties were characterized using metal-insulator semiconductor (MIS) capacitors and photodiodes implemented with UV enhanced chemical vapor deposition (CVD) oxide/PNOX/InSb. Interface state densities of 2–4×1011 cm−2 eV−1 are obtained with good uniformity and stability. The hysteresis of the MIS structure with 1000 Å photoinduced CVD oxide on PNOX is very small, about 0.32 V for a ±20 V span measured at 77 K.
Ionic liquids: the view from Mount Improbable (2016)

The ionic liquid literature has grown at a remarkable rate since 1998, making it increasingly difficult to assess the important research directions and the underlying, fundamental understanding of ionic liquids.
Epidemiology of knee osteoarthritis in general practice: a registry-based study (2020)

Increased prevalence, multimorbidity, and number of drug prescriptions confirm an increased burden of knee osteoarthritis. In future, these trends can be used to prioritise initiatives for improvement in care.
Addition of Candesartan to Angiotensin Converting Enzyme Inhibitor Therapy in Patients with Chronic Heart Failure Does not Reduce Levels of Oxidative Stress (2002)

The addition of the candesartan to ACE inhibitor therapy had no effect on oxidative stress and did not improve endothelial function or exercise capacity in patients with CHF.