gebhart/patrepeval huggingface dataset:
Dynamic response time optimization for SDF graphs (2000)

Synchronous Data Flow (SDF) is a well-known model of computation that is widely used in the control engineering and digital signal processing domains. Existing scheduling methods are mainly static approaches that assume full knowledge of the environment, e.g. data arrival times. In a growing number of practical cases like internet multimedia applications there exists only partial knowledge of the environment, e.g. average data rates. Here, only dynamic scheduling can yield optimal results. In this paper, we propose a new dynamic scheduling method that minimizes the maximal response time of the system. It is a generalization of a deadline revision method to allow treatment of data-dependent tasks using EDF scheduling. The applicability and benefit of the new approach is shown using a real-world example.
Peritoneal Dialysis: Adequacy beyond Kt/V (1999)

nique to the patient is a real obligation for the nephrologist. The patient must be correctly informed and educated throughout the period of progression of the renal disease. During periodic hospitalizations or dayhospital activities, adequate information should be coupled with accurate clinical and social evaluation. With this program of staff interventions, the patient will choose a technique with knowledge, freedom, and safety. The main message is that different techniques are interchangeable, with the possibility of free access to all of them (if clinically possible) and an easy transfer among them. Patient information and education can be adequate only when the staff (both nurses and doctors) are fully convinced that PD should be con sidered at the same level with other techniques. Furthermore, family collaboration, and contacts with other patients with positive experiences, should be encouraged. Once the patient has been informed of advantages and disadvantages, and family support has been assessed, the patient will be helped in making a choice by a reliable hospital team, and that choice will be accompanied by a good feeling of freedom and safety. At this point, from the ethical point ofview, all efforts will have been made to achieve an effective integration ofPD into the treatment of uremia. ORGANIZATIONAL
Silicon Photonics (2013)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text M. Lipson, "Silicon Photonics," in Frontiers in Optics 2013, I. Kang, D. Reitze, N. Alic, and D. Hagan, eds., OSA Technical Digest (online) (Optica Publishing Group, 2013), paper FM4E.2. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Precipitation of Tellurium‐Rich Phase in Heavily Diethyltellurium‐Doped GaAs during Organometallic Vapor Phase Epitaxy (1995)

layers were heavily doped with liquid source diethyltellurium (DETe) during organometallic vapor phase epitaxy. Samples were characterized by Hall effect measurements and transmission electron microscopy (TEM). The electron concentration was observed to saturate at for high DETe flows, which is independent of growth temperature in the investigated range from 475 to 600°C. TEM examination revealed the presence of precipitates in layers doped above the saturation level. The precipitates were Te‐rich by energy dispersive x‐ray analysis. Electron diffraction study showed that they have the zinc‐blende structure with a lattice constant of 6.5 Å. The appearance of tellurides at high doping levels indicates that the formation of a second phase could be one of the main mechanisms responsible for the carrier saturation in Te‐doped . The liquid source DETe causes persistent memory effects associated with the adsorption of DETe on the stainless steel tube walls of the gas distribution system.
Antibodies to liposomal phosphatidylcholine and phosphatidylsulfocholine (1990)

Antibodies against dimyristoyl phosphatidylsulfocholine or dimyristoyl phosphatidylcholine were raised in rabbits after injection of liposomes containing phosphatidylsulfocholine or phosphatidylcholine, cholesterol, and lipid A. The antibody activities were assayed by complement-dependent immune damage to liposomes and by a solid-phase, enzyme-linked immunosorbent assay using purified dimyristoyl phosphatidylcholine or dimyristoyl phosphatidylsulfocholine as antigen. Each antiserum raised against phosphatidylsulfocholine reacted with liposomes containing phosphatidylcholine, and each antiserum raised against phosphatidylcholine reacted with liposomes containing phosphatidylsulfocholine. However, adsorption of dimyristoyl phosphatidylsulfocholine antiserum with liposomes containing dimyristoyl phosphatidylcholine removed all activity against dimyristoyl phosphatidylcholine, but did not eliminate antibody activity against dimyristoyl phosphatidylsulfocholine. These results indicate that the antiserum against phosphatidylsulfocholine contained mixed populations of antibodies. Polyclonal antisera that have been appropriately adsorbed can therefore be obtained with a high degree of specificity for phosphatidylsulfocholine and such antisera can distinguish between phosphatidylsulfocholine and phosphatidylcholine.
Implicit Rugosity Regularization via Data Augmentation (2019)

Deep (neural) networks have been applied productively in a wide range of supervised and unsupervised learning tasks. Unlike classical machine learning algorithms, deep networks typically operate in the \emph{overparameterized} regime, where the number of parameters is larger than the number of training data points. Consequently, understanding the generalization properties and the role of (explicit or implicit) regularization in these networks is of great importance. In this work, we explore how the oft-used heuristic of \emph{data augmentation} imposes an {\em implicit regularization} penalty of a novel measure of the \emph{rugosity} or "roughness" based on the tangent Hessian of the function fit to the training data.
Vaccines 85 : molecular and chemical basis of resistance to parasitic, bacterial, and viral diseases (1985)

This book contains 70 selections. Some of the selection titles are: Structure of the Gene Encoding of Immunodominant Surface Antigen on the Sprozoite of the Human Malaria Parasite Plasmodium falciparum; Cloning and Expression in Bacteria of the Genes for Merozite-specific Antigens from the Malaria Parasite Plasmodium falciparum; A Major Surface Antigen of Plasmodium falciparum in Merozoites: Studies on the Protein and its Gene; Genetic Construction of Cholera Vaccine Prototypes; and Viral Genes, Cytotoxic T Lymphocytes and Immunity.
Predictions of Transient Flame Lift-Off Length With Comparison to Single-Cylinder Optical Engine Experiments (2013)

A state-of-the-art, grid-convergent simulation methodology was applied to three-dimensional calculations of a single-cylinder optical engine. A mesh resolution study on a sector-based version of the engine geometry further verified the RANS-based cell size recommendations previously presented by Senecal et al. [1]. Convergence of cylinder pressure, flame lift-off length and emissions was achieved for an adaptive mesh refinement cell size of 0.35 mm. Full geometry simulations, using mesh settings derived from the grid convergence study, resulted in excellent agreement with measurements of cylinder pressure, heat release rate and NOx emissions. On the other hand, the full geometry simulations indicated that the flame lift-off length is not converged at 0.35 mm for jets not aligned with the computational mesh. Further simulations suggested that the flame lift-off lengths for both the non-aligned and aligned jets appear to be converged at 0.175 mm. With this increased mesh resolution, both the trends and magnitudes in flame lift-off length were well predicted with the current simulation methodology. Good agreement between the overall predicted flame behavior and the available chemiluminescence measurements was also achieved. The present study indicates that cell-size requirements for accurate prediction of full geometry flame lift-off lengths may be stricter than those for global combustion behavior. This may be important when accurate soot predictions are required.
On dynamic data-driven selection of sensor streams (2011)

Sensor nodes have limited local storage, computational power, and battery life, as a result of which it is desirable to minimize the storage, processing and communication from these nodes during data collection. The problem is further magnified by the large volumes of data collected. In real applications, sensor streams are often highly correlated with one another or may have other kinds of functional dependencies. For example, a group of sound sensors in a given geographical proximity may pick almost the same set of signals. Clearly, since there are considerable functional dependencies between different sensors, there are huge redundancies in the data collected by sensors. These redundancies may also change as the data evolve over time. In this paper, we discuss real time algorithms for reducing the volume of the data collected in sensor networks. The broad idea is to determine the functional dependencies between sensor streams efficiently in real time, and actively collect the data only from a minimal set of sensors. The remaining sensors collect the data passively at low sampling rates in order to detect any changing trends in the underlying data. We present real time algorithms in order to minimize the power consumption in reducing the data collected and show that the resulting data retains almost the same amount of information at a much lower cost.
Oxidative cleavage of carbon–silicon bonds by dioxygen: catalysis by a flavin–dihydronicotinamide redox system (1988)

Carbon–silicon bonds in alkoxy- or fluoro-silanes readily undergo cleavage by dioxygen (molecular oxygen), catalysed by tetra-acetylriboflavin (5–10 mol%) in the presence of N-benzyl-1,4-dihydronicotinamide as reductant, together with fluoride ions as an essential additive.
Negative Databases for Biometric Data (2010)

Negative databases - negative representations of a set of data - have been introduced in 2004 to protect the data they contain. Today, no solution is known to constitute biometric negative databases. This is surprising as biometric applications are very demanding of such protection for privacy reasons. The main difficulty comes from the fact that biometric captures of the same trait give different results and comparisons of the stored reference with the fresh captured biometric data has to take into account this variability. In this paper, we give a first answer to this problem by exhibiting a way to create and exploit biometric negative databases.
Abstract 2841: Widespread endothelial cell infection and tumor cell apoptosis after intravenous injection of oncolytic vaccinia virus JX-594 into RIP-Tag2 mice. (2013)

Abstract Replication-competent oncolytic viruses are being developed as a promising strategy for treating certain types of cancer. JX-594 is an oncolytic vaccinia virus that lacks thymidine kinase and expresses human granulocyte-macrophage colony stimulating factor (hGM-CSF). Replication of JX-594 is promoted by EGFR/Ras pathway signaling in cancer cells. In addition to having direct oncolytic effects on tumor cells and recruiting an immune response, JX-594 has been found to cause rapid reduction of tumor blood flow in preclinical models and in clinical trials. To understand the mechanism of this vascular effect, we injected mouse-adapted JX-594 vaccinia virus (mJX-594, on Western Reserve backbone and expressing hGM-CSF) intravenously into RIP-Tag2 transgenic mice and examined the pancreatic neuroendocrine tumors at 6 hours or 1, 2, or 5 days after injection. Dot-like vaccinia immunoreactivity was widespread in endothelial cells of tumor vessels at 6 hours. Scattered endothelial cells had intense staining. Vaccinia immunoreactivity in tumor blood vessels was still widespread at 1 day, but at 5 days, most tumor vessels were narrowed, some appeared fragmented, and tumor vascularity was reduced by 40%. Normalization of tumor vessels, as observed after inhibition of VEGF signaling, was not found at any time examined. Intratumoral hypoxia was evident as diffuse regions of pimonidazole staining at 6 hours. Pimonidazole staining increased from 1 to 5 days, and was especially strong in regions of vascular pruning. Extravascular vaccinia immunoreactivity was located in scattered cells at 1 day and increased with time. At 5 days, most tumors had large patches of vaccinia-positive cells. This staining was not present in the surrounding normal acinar pancreas. Apoptotic cells stained for activated caspase-3 were scattered throughout tumors at 6 hours. Most of these apoptotic cells were endothelial cells. Apoptotic tumor cells were sparse at 6 hours, but at 5 days apoptotic cells were 23-fold more numerous than at baseline and even more widespread than vaccinia immunoreactivity, and tumors tended to be smaller than corresponding controls. These findings are consistent with oncolytic virus mJX-594 causing rapid infection of tumor vascular endothelial cells in RIP-Tag2 mice. Endothelial cell infection is followed by regression of tumor blood vessels, exaggeration of intratumoral hypoxia, and oncolytic actions on tumor cells that lead to widespread tumor cell apoptosis. Citation Format: Barbara Sennino, Brian J. Schriver, Caroline J. Breitbach, Naomi De Silva, John C. Bell, David H. Kirn, Donald M. McDonald. Widespread endothelial cell infection and tumor cell apoptosis after intravenous injection of oncolytic vaccinia virus JX-594 into RIP-Tag2 mice. [abstract]. In: Proceedings of the 104th Annual Meeting of the American Association for Cancer Research; 2013 Apr 6-10; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2013;73(8 Suppl):Abstract nr 2841. doi:10.1158/1538-7445.AM2013-2841
ADF/cofilin mediates actin cytoskeletal alterations in LLC-PK cells during ATP depletion (2003)

Ischemic injury induces actin cytoskeleton disruption and aggregation, but mechanisms affecting these changes remain unclear. To determine the role of actin-depolymerizing factor (ADF)/ cofilin participation in ischemic-induced actin cytoskeletal breakdown, we utilized porcine kidney cultured cells, LLC-PK(A4.8), and adenovirus containing wild-type (wt), constitutively active, and inactive Xenopus ADF/cofilin linked to green fluorescence protein [XAC(wt)-GFP] in an ATP depletion model. High adenoviral infectivity (70%) in LLC-PK(A4.8) cells resulted in linearly increasing XAC(wt)-GFP and phosphorylated (p)XAC(wt)-GFP (inactive) expression. ATP depletion rapidly induced dephosphorylation, and, therefore, activation, of endogenous pcofilin as well as pXAC(wt)-GFP in conjunction with the formation of fluorescent XAC(wt)-GFP/actin aggregates and rods. No significant actin cytoskeletal alterations occurred with short-term ATP depletion of LLC-PK(A4.8) cells expressing GFP or the constitutively inactive mutant XAC(S3E)-GFP, but cells expressing the constitutively active mutant demonstrated nearly instantaneous actin disruption with aggregate and rod formation. Confocal image three-dimensional volume reconstructions of normal and ATP-depleted LLC-PK(A4.8) cells demonstrated that 25 min of ATP depletion induced a rapid increase in XAC(wt)-GFP apical and basal signal in addition to XAC-GFP/actin aggregate formation. These data demonstrate XAC(wt)-GFP participates in ischemia-induced actin cytoskeletal alterations and determines the rate and extent of these ATP depletion-induced cellular alterations.
Enhanced inactivation of bacteria by metal‐oxide nanoparticles combined with visible light irradiation (2011)

The results suggest that nanoparticles combined with visible light can be used for sterilization purposes and may be effective for treating infected wounds.
INS/GPS data fusion technique utilizing radial basis functions neural networks (2004)

Most of the present navigation systems rely on Kalman filtering methods to fuse data from global positioning system (GPS) and the inertial navigation system (INS). In general, INS/GPS integration provides reliable navigation solutions by overcoming each of their shortcomings, including signal blockage for GPS and growth of position errors with time for INS. Present Kalman filtering INS/GPS integration techniques have several inadequacies related to sensor error model, immunity to noise and observability. This paper aims at introducing a multi-sensor system integration approach for fusing data from an INS and GPS hardware utilizing artificial neural networks (ANN). A multi-layer perceptron ANN has been recently suggested to fuse data from INS and differential global positioning system (DGPS). Although of being able the positioning accuracy, the complexity associated with both the architecture of multilayer perceptron networks and its online training algorithms limit the real time capabilities of this techniques. This article, therefore, suggests the use of an alternative ANN architecture. This architecture is based on radial basis function (RBF) neural networks, which generally have simpler architecture and faster training procedure than multi-layer perceptron networks. The INS and GPS data are first processed using wavelet multiresolution analysis (WRMA) before being applied to RBF network. The WMRA is used to compare the INS and GPS position outputs at different resolution levels. The RBF-ANN module is then trained to predict the INS position errors in real-time and provide accurate positioning of the moving platform. The field-test results have demonstrated that substantial improvement in INS/GPS positioning accuracy could be obtained by applying the combined WRMA and RBF-ANN modules.
Gradient Induced Sideband Artifacts in non Water-Suppressed Proton CSI of the Human Brain at 9.4 T (2013)

CSI without water suppression offers several advantages, like the possibility to use the water signal for absolute quantification. However, the unsuppressed spectra are hampered by gradient induced sidebands, which have to be removed before the quantification. Despite known difficulties (shorter T2 relaxation time, larger B0 and B1 inhomogeneities), previous studies demonstrated that CSI at ultra-high magnetic field is feasible. The aim of this study was to verify the feasibility of short TE proton CSI on the human brain without water suppression at the field strength of 9.4 T and to examine the influence of sidebands on the measured spectra.
A biodegradable antibiotic-impregnated scaffold to prevent osteomyelitis in a contaminated in vivo bone defect model (2014)

Open fractures are at risk of serious infection and, if infected, require several surgical interventions and courses of systemic antibiotics. We investigated a new injectable formulation that simultaneously hardens in vivo to form a porous scaffold for bone repair and delivers antibiotics at high concentrations to the local site of infection. Duration of antimicrobial activity against Staphylococcus aureus was determined using the serial plate transfer test. Ultimate compressive strength and porosity of the material was measured with and without antibiotics. The material was evaluated in vivo in an ovine medial femoral condyle defect model contaminated with S. aureus. Sheep were sacrificed at either 2 or 13 weeks and the defect and surrounding bone assessed using micro-computed tomography and histology. Antimicrobial activity in vitro persisted for 19-21 days. Sheep with antibiotic-free material and bacteria became infected, while those with antibiotic-containing material and bacteria did not. Similarly, new bone growth was seen in uninoculated animals with plain polymer, and in those with antibiotic polymer with bacteria, but not in sheep with plain polymer and bacteria. The antibiotic-impregnated scaffolds were effective in preventing S. aureus infections whilst supporting bone growth and repair. If translated into clinical practice, this approach might reduce the need for systemic antibiotics.
SMOS instrument performance and calibration (2012)

This paper presents the progress made in the calibration and image reconstruction of the brightness temperature data provided by the SMOS mission of the European Space Agency. This progress has been made thanks to the learning through the accumulation of results since the launch of the satellite. Current performance of the payload on-board SMOS, the MIRAS interferometer, our main findings on its behavior and open lines of investigation are included in this contribution.
How Many Sensors to Localize the Source? The Double Metric Dimension of Random Networks (2018)

We consider the problem of detecting the source of an epidemic that spreads in a network. The only information about the epidemic comes from a subset of nodes, which we call sensors, and which can reveal if and when they become infected. How many sensors do we need to guarantee that the epidemic source is correctly identified? The answer to this question is a known network property, called the double metric dimension (DMD); unfortunately, it is hard to compute. We compute tight bounds for the DMD of g(N, p) random networks. Interestingly, these bounds are non-monotonic functions of the edge density p: this implies in turn that the detectability of the source is influenced by the edge density p in a non-monotonic fashion in g(N, p) networks. We show empirically that this property applies to other topologies as well.
Interactions between IL-Ibêta, IL-6, IL-8, and LIF produced by human articular chondrocytes (1994)

peer reviewed
Silicon photonic WDM devices: simulation, design, and implementation (2009)

Passive wavelength division (de)multiplexer (WDM) devices are required as basic building blocks for WDM-based on-chip optical interconnects. In this application, many copies of the devices will be placed throughout a single die, requiring that the device occupy as small a footprint as possible. Furthermore, it is critical that the demultiplexing characteristics be very uniform from device to device, therefore the device must be tolerant to small fabrication variations. There are various wavelength demultiplexer designs that lend themselves to on-chip integration with CMOS integrated circuits and that could potentially reach the above specifications. In this presentation we will show the layout and simulation of demultiplexer designs based on cascaded Mach-Zehnder wavelength splitters and on Echelle gratings and compare these to measurement results of realized devices. The results on the Mach-Zehnder devices show that this type of device is relatively sensitive to process variations. A fit of a device model to the measured curves shows that the device variations result primarily from random phase errors in the optical delay lines, which are probably due to small width variations in the waveguides. This problem should be strongly reduced in devices based on Echelle gratings, because in this case the light does not propagate through channel waveguides in the part of the device that shapes the optical response. This assumption is confirmed by the measurement results, which show good demultiplexer response and excellent reproducibility between devices.
Thermally Stable Type II FBGs Written Through Polyimide Coatings of Silica-Based Optical Fiber (2017)

Type II-IR fiber Bragg gratings (FBGs) were written directly through the protective polyimide coatings of off-the-shelf pure silica core and standard telecom Ge-doped silica core single mode fibers using ultrafast IR radiation and the phase mask FBG writing method. Using a short focal length acylindrical lens and nonlinear photoluminescent imaging, type II grating structures could be created when Fourier transform limited pulses were chirped to 500 fs. The resulting gratings in the Ge-doped fibers were thermally stable up to 1000 °C and could be used directly as fabricated without annealing to stabilize the structure.