gebhart/patrepeval huggingface dataset:
Correlating the Structural and Photophysical Features of Pincer Luminophores and Monodentate Ancillary Ligands in PtII Phosphors (Eur. J. Inorg. Chem. 36/2015) (2015)

The cover picture shows the molecular structure of three bright PtII complexes bearing tridentate pyridine-bis(azolyl) luminophores with different substitution patterns. Enhanced photoluminescence quantum yields are obtained if diazole units are combined with bulky adamantyl moieties and triphenylphosphine ancillary ligands. In particular, the charge-transfer character of the excited state is enhanced when triazole rings are replaced by diazoles, and aggregation-mediated quenching can be suppressed even in the solid state. Details are discussed in the article by L. De Cola, C. A. Strassert et al. on p. 5822 ff. For more on the story behind the cover research, see the Cover Profile.
Mimicking fire scenarios at the reduced scale: case studies for aircraft and cables (2020)

International audience
450mm etch process development and process chamber evaluation using 193i DSA guided pattern (2016)

In the Global 450mm Equipment Development Consortium (G450C), a 193i guided directed self-assembly (DSA) pattern has been used to create structures at the 14nm node and below. The first guided DSA patterned wafer was ready for etch process development within a month of the G450C’s first 193i patterned wafer availability with one litho pass. Etch processes were scaled up from 300mm to 450mm for a 28nm pitch STI stack and a 40nm pitch M1 BEOL stack. The effects of various process parameters were investigated to fine tune each process. Overall process window has been checked and compared. Excellent process stability results were shown for current etch chambers.
Statistical modeling of propagation channels for Terahertz band (2017)

Digital revolution and recent advances in telecommunications technology enable to design communication systems which operate within the regions close to the theoretical capacity limits. Ever-increasing demand for wireless communications and emerging numerous high-capacity services and applications mandate providers to employ more bandwidth-oriented solutions to meet the requirements. Trend and predictions point out that marketplace targets data rates around 10Gbps or even more within the upcoming decade. It is clear that such rates could only be achieved by employing more bandwidth with the state-of-the-art technology. Considering the fact that bands in the range of 275GHz-3000GHz, which are known as Terahertz (THz) bands, are not allocated yet for specific active services around the globe, there is an enormous potential to achieve the desired data rates. Although THz bands look promising to achieve data rates on the order of several tens of Gbps, realization of fully operational THz communications systems obliges to carry out a multidisciplinary effort including statistical propagation and channel characterizations, adaptive transceiver designs, reconfigurable platforms, advanced signal processing algorithms and techniques along with upper layer protocols equipped with various security and privacy levels. Therefore, in this study, several important statistical parameters for line-of-sight (LOS) channels are measured. High resolution frequency domain measurements are carried out at single-sweep within a span of 60GHz. Impact of antenna misalignment under LOS conditions is also investigated. By validating exponential decay of the received power in both time and frequency domain, path loss exponent is examined for different frequencies along with the frequency-dependent path loss phenomenon. Furthermore, impact of humidity is also tested under LOS scenario. Measurement results are presented along with relevant discussions and future directions are provided as well.
Argos (2012)

Multi-user multiple-input multiple-output theory predicts manyfold capacity gains by leveraging many antennas on wireless base stations to serve multiple clients simultaneously through multi-user beamforming (MUBF). However, realizing a base station with a large number antennas is non-trivial, and has yet to be achieved in the real-world. We present the design, realization, and evaluation of Argos, the first reported base station architecture that is capable of serving many terminals simultaneously through MUBF with a large number of antennas (M >> 10). Designed for extreme flexibility and scalability, Argos exploits hierarchical and modular design principles, properly partitions baseband processing, and holistically considers real-time requirements of MUBF. Argos employs a novel, completely distributed, beamforming technique, as well as an internal calibration procedure to enable implicit beamforming with channel estimation cost independent of the number of base station antennas. We report an Argos prototype with 64 antennas and capable of serving 15 clients simultaneously. We experimentally demonstrate that by scaling from 1 to 64 antennas the prototype can achieve up to 6.7 fold capacity gains while using a mere 1/64th of the transmission power.
Subjective Assessment of Cochlear Implant Users’ Signal-to-Noise Ratio Requirements for Different Levels of Wireless Device Usability (2014)

The results for the CI users in terms of both preferred levels for wireless and cordless phone communication and signal-to-noise requirements closely paralleled the corresponding results for hearing aid users from the previous study, and showed no significant differences between the microphone and telecoil modes of use. Signal-to-noise requirements were directly related to the participants' noise audibility threshold and were independent of noise type when appropriate noise-measurement weighting was applied. Extending the investigation to include noncontinuous interfering noises and forms of radiofrequency interference other than additive audiofrequency noise could be areas of future study.
Pro-apoptotic role of integrin β3 in glioma cells (2011)

Malignant gliomas are the most destructive type of brain cancer. In order to gain a better understanding of the molecular mechanisms of glioma cell death and survival, we previously established an alkylating agent 1, 3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-resistant variant of C6 rat glioma cells. Proteomic analysis indicated a significant down-regulation of integrin beta 3 (ITGB3) in the BCNU-resistant C6R cells. Re-expression of ITGB3 in C6R cells restored the BCNU sensitivity. In U87MG, U373MG, and T98G human glioma cells, there was a positive correlation between ITGB3 expression and the sensitivity to BCNU and etoposide, suggesting an important role of ITGB3 in glioma cell death. Over-expression of ITGB3 cDNA significantly increased the sensitivity of the human glioma cells to the anticancer drug-induced apoptosis. Nitric oxide showed an additive effect on the anticancer drug-induced glioma cell death by increasing ITGB3 expression. Subsequent dissection of signaling pathways indicated that extracellular signal-regulated kinase and unligated integrin-mediated cell death pathway may be involved in the pro-apoptotic role of ITGB3 in glioma cells. These results implicate ITGB3 in glioma cell death/survival and drug resistance.
Deep Temporal Multimodal Fusion for Medical Procedure Monitoring Using Wearable Sensors (2017)

Process monitoring and verification have a wide range of uses in the medical and healthcare fields. Currently, such tasks are often carried out by a trained specialist, which makes them expensive, inefficient, and time-consuming. Recent advances in automated video- and multimodal-data-based action and activity recognition have made it possible to reduce the extent of manual intervention required to effectively carry out process supervision tasks. In this paper, we propose algorithms for automated egocentric human action and activity recognition from multimodal data, with a target application of monitoring and assisting a user perform a multistep medical procedure. We propose a supervised deep multimodal fusion framework that relies on concurrent processing of motion data acquired with wearable sensors and video data acquired with an egocentric or body-mounted camera. We demonstrate the effectiveness of the algorithm on a public multimodal dataset and conclude that automated process monitoring via the use of multiple heterogeneous sensors is a viable alternative to its manual counterpart. Furthermore, we demonstrate that the application of previously proposed adaptive sampling schemes to the video processing branch of the multimodal framework results in significant performance improvements.
Achieving Grain Refinement of Upsized Al–3Mg–0.2Sc (mass%) Round Rods Using Multi-Pass High-Pressure Sliding (MP-HPS) (2020)

In this study, the multi-pass high-pressure sliding (MP-HPS) process was applied for grain refinement of Al–3Mg–0.2Sc (mass%) rods with an upsized dimension of 16 mm in diameter. To achieve a homogeneous microstructure throughout the cross-section, the rod sample was rotated with 60° around the longitudinal axis (MP-HPS-R) for three times. A microstructure with an average grain size of 280 nm was developed around the center of the cross-section through the MP-HPS-R process. Superplasticity with total elongations of more than 400% was achieved in the 9 mm diameter range on the cross-section of the MP-HPS-R-processed rod.
DYSSYNCHRONOUS APRAXIA: FAILURE TO COMBINE SIMULTANEOUS PREPROGRAMMED MOVEMENTS (1998)

Limb apraxia, a defect in skilled, learned purposive movement, may be related to impairment of either representational or innervatory components of praxis processing. Innervatory motor patterns, in turn, may involve on-line motor programs (visual feedback-controlled) or prepared movement programs (independent of continuous visual feedback). We evaluated movement abilities ofthe innervatory pattern system in TB,a 26-year-old patient with apraxia from a left dorsolateral frontal stroke. TB and four controls performed nonmeaningful single and multi-joint movements to command, with multi-joint movements combined sequentially (e.g. "open and close your hand and then bend your elbow") or simultaneously (e.g. "open and close your hand; keep doing that while bending your elbow"). TB showed no difference between single-joint (71.5% correct) and multi-joint movements in sequential combinations (68% correct), but she was significantly worse at simultaneous movement combinations (28.6% correct; P < .02). Controls performed consistently at > 90% mean accuracy. TB and four normals also performed the Fitts (1954) task, in which they alternately tapped with a pen between two target circles of varying size. TB was proportionately slower than controls on the larger Fitts circles, which call predominantly on prepared movement programs; her performance on the smaller circles (involving more on-line programs) was comparable to normals. We conclude that functional synchrony of one innervatory pattern subtype, prepared movement programs, may require late-level frontal processing, and that failure at this level can result in both apraxia and defective programming of nonmeaningful movements.
Abstract P131: The Effects of Weight Loss on Liver Function in Obese Hypertensive Patients (2012)

Objective: Insulin resistance and visceral adiposity are predisposing factors for fatty liver disease. This study was undertaken to evaluate the weight loss effects on liver function (ALT, AST, GGT). Methods: 90 overweight/obese, mild hypertensive men without medications or liver dysfunction were randomized into the 3 weight loss (WL) regimens over 24 weeks. WL was achieved with i) a mild calorie restricted diet alone (D alone; 1800kcal/day, 55% carbohydrate, 30% protein, 15% fat), ii) mild exercise alone (EX alone; 1-hr walking), or iii) a combination with a mild calorie restricted diet + exercise (D+EX) over 24 weeks. BMI, waist/hip ratio (W/H), total body fat-mass, blood pressure (BP), plasma norepinephrine (NE), fasting insulin, glucose, HOMA-IR, total cholesterol (Tch), triglyceride (TG), and liver function (ALT, AST, GGT) were measured every 4 weeks over 24 weeks with WL. Results: At entry period, BMI, fat-mass, W/H, BP levels, plasma NE, HOMA-IR, Tch, TG, ALT, AST, and GGT were similar between the 3 groups. At 24 weeks, the D+EX group had significantly higher prevalence of normalizations of BMI and BP levels (53.3%, 56.7%, respectively) compared to the D alone (13.3%, 23.3%, 30.0%) or EX alone (26.6%, 23.3%). In the D alone group, significant decreases in plasma NE and TG was observed at 2 weeks followed by significant reductions in Tch, body weight, fat mass, and HOMA at 8 weeks. Significant reductions in W/H, BP and GGT were also observed at 8 weeks, and ALT and AST decreased gradually but significantly at 12 weeks. On the other hand, in the EX alone group, significant fat loss and significant reduction in W/H, HOMA-IR and GGT were observed at 4 weeks. Body weight and plasma NE decreased significantly at 8 weeks, and significant BP reduction and decreases in TG and Tch were occurred at 12 weeks followed by decreases in ALT and AST at 16 weeks. Reductions in GGT were similar between the D alone and D+EX groups, but the groups including D had greater reduction in GGT, ALT and AST compared to the EX alone group. In the combination group (D+EX group), every improvement was observed earlier and stronger. Significant suppression on plasma NE and TG was at 2 weeks, decreases in HOMA, Tch, weight, fat-mass, W/H, systolic BP and GGT were at 4 weeks, and diastolic BP, ALT, and AST were at 8 weeks. In all subjects, reductions in HOMA-IR preceded to decreases in liver function parameters (GGT, ALT, and AST), and reductions in GGT was followed by decreases in ALT or AST. In multiple regression analyses, at both period of entry and 24-week, HOMA-IR was a significant determinant for GGT, TG and Tch. At entry and 24-week periods, Tch, but not TG, was a significant determinant for GGT, ALT, and AST. Conclusions: Improvement of insulin resistance associated with WL may play an important role of improvement of liver function during lifestyle modifications. WL is an effective treatment for fatty liver disease associated with obesity.
Antifibrillatory Effect of Esmolol Alone and in Combination with Lidocaine (1996)

The primary objective of this study was to determine the effect of esmolol, administered alone and in combination with lidocaine, on ventricular fibrillation threshold (VFT) in pigs. A secondary objective was to determine the relationship between blood esmolol concentrations and VFT. We determined VFT using a train of electrical stimuli delivered to the right ventricle after eight paced beats at a basic cycle length of 285 ms. Current was increased in 2-mA increments until VF occurred. VFT determinations were performed during administration of esmolol 1,000 mu g/kg/min, during a continuous infusion of lidocaine, and during infusion of esmolol and lidocaine in combination. Mean increases in VFT from baseline during infusion of esmolol and lidocaine alone were 32.3 +/- 12.9 and 8.5 +/- 7.2 mA, respectively (p < 0.05, each drug compared with baseline; p < 0.05, esmolol vs. lidocaine). Mean increase in VFT from baseline during infusion of the combination was 52.0 +/- 22.0 mA (p < 0.05 as compared with baseline and with esmolol or lidocaine alone). The relationship between blood esmolol concentrations and VFT was described by a counterclockwise hysteresis curve, suggesting delay in equilibration of esmolol between blood and site of effect. The antifibrillatory efficacy of esmolol is significantly greater than that of lidocaine in this model. Administration of the two agents in combination resulted in significantly greater antifibrillatory efficacy than that associated with either drug administered alone.
90$^{\circ}$ Light Beam Deflection Technology for Single-Mode Optical Interconnection Systems (2007)

In this letter, we demonstrate an extremely low loss (<0.06 dB) 1-mm bending radius 90deg light deflection by using a 12-single-mode-fiber ribbon for optical interconnection systems. This technology is easy to be adopted for optical surface mount assemblies that need light beam deflection between the vertical surface-emitting lasers or surface-receiving photodiodes and optical paths parallel to an electric circuit board. We have chosen single-mode fiber (SMF) for the 90deg-bent fiber expecting the single-mode transmission will be applied for high-performance optical interconnection systems because of its wide bandwidth and stability in transmission characteristics. In order to minimize the bending loss and accomplish a small bending radius, we have developed a new optical fiber having higher refractive index of the core (high delta n fiber) than that of conventional fiber and 80-mum-cladding 125-mum spacing 12-fiber ribbon for dense packaging and easy handling in narrow spaces. It is bent at a radius of 1 mm by heating process with a ceramic heater.
Diminishing returns? (2011)

The computing performance literature offers guidelines and frameworks, but data on the limits of user appreciation for performance are scarce. This paper presents a study of user satisfaction with different levels of computing performance. Thirty-five participants performed common computing tasks such as creating email and Web surfing. They rated computing performance for specific task elements - such as application launching and menu responsiveness - that occurred during those tasks. They repeated the tasks under varying levels of computer performance. Results include user ratings as a function of computing performance for each of the task elements. The results have implications for system designers who create products that must meet user expectations for performance.
Continuous cyclo-polymerisation of l-lactide by reactive extrusion using atoxic metal-based catalysts: easy access to well-defined polylactide macrocycles (2015)

Macrocyclic polylactide was synthesized by reactive extrusion polymerisation of <sc>l</sc>-lactide using lanthanide trisborohydrides as the catalysts. This is the first example of a cyclic polyester obtained directly <italic>via</italic> a continuous process.
Noise-robust dynamic time warping using PLCA features (2012)

Conventional speech features, such as mel-frequency cepstral coefficients, tend to perform well in template matching systems, such as dynamic time warping, in low noise conditions. However, they tend to degrade in noisy environments. We propose a method of calculating features using the probabilistic latent component analysis (PLCA) framework. This framework models the speech and noise separately, leading to higher performance in noisy conditions than conventional methods. In this work, we compare our PLCA-based features with conventional features on the task of aligning a high-fidelity speech recording to a noisy speech recording, a scenario common in automatic dialogue replacement.
Cytokines in Acute Myocardial Infarction (1994)

Summary Cytokines play a pathogenetic role in a variety of infective and inflammatory diseases. In the present study, we had two objectives: (a) to define the kinetics of tumor necrosis factor (TNF) in plasma after acute myocardial infarction (AMI) in patients treated with early thrombolysis, and (b) to measure other cytokines, interleukin-1 (IL-1) and TNF receptor antagonists, in plasma. TNF-α, but not IL-1β(3 or IL-8, was present in plasma of 6 of 7 patients with severe AMI (Killip class 3 or 4). No TNF (<50 pg/ml) was detected in a group of 11 patients with uncomplicated myocardial infarction (Killip class 1) or in control patients without AMI. Soluble TNF receptor type I and IL-1 receptor antagonist (IL-1Ra) were also significantly increased in the group with severe AMI compared with those with uncomplicated AMI. Circulating TNF is increased only in AMI complicated by heart failure at hospital admission. This finding may have diagnostic and therapeutic relevance.
Evolution of cooperation in networked heterogeneous fluctuating environments (2019)

Fluctuating environments are situations where the spatio-temporal stochasticity plays a significant role in the evolutionary dynamics. The study of the evolution of cooperation in these environments typically assumes a homogeneous, well mixed population, whose constituents are endowed with identical capabilities. In this paper, we generalize these results by developing a systematic study for the cooperation dynamics in fluctuating environments under the consideration of structured, heterogeneous populations with individual entities subjected to general behavioral rules. Considering complex network topologies, and a behavioral rule based on generalized reciprocity, we perform a detailed analysis of the effect of the underlying interaction structure on the evolutionary stability of cooperation. We find that, in the presence of environmental fluctuations, the cooperation dynamics can lead to the creation of multiple network components, each with distinct evolutionary properties. This is paralleled to the freezing state in the Random Energy Model. We utilize this result to examine the applicability of our generalized reciprocity behavioral rule in a variety of settings. We thereby show that the introduced rule leads to steady state cooperative behavior that is always greater than or equal to the one predicted by the evolutionary stability analysis of unconditional cooperation. As a consequence, the implementation of our results may go beyond explaining the evolution of cooperation. In particular, they can be directly applied in domains that deal with the development of artificial systems able to adequately mimic reality, such as reinforcement learning.
Ergodic Sum Capacity of Spectrum-Sharing Multiple Access with Collision Metric (2013)

This paper investigates the ergodic sum capacity of a spectrum-shared Multiple Access Channel (MAC). We assume that the secondary service (SS) only knows the channel distribution information (CDI) between its transmitters and the primary receivers. Availability of CDI results in collision incidences at the primary receivers because of conflicting levels of intolerable interference. We introduce the concept of collision probability constraint to manage the unexpected QoS degradation of primary service in the secondary resource allocation (RA). This RA problem is inherently difficult to solve and its objective function is not necessarily convex. Two well-known approaches, called Iterative Approach (IA) and Analytical Approach (AA), each with several cases/categories, are then used to find solutions. IA solves the problem iteratively by reconstructing convex optimization problems from the original (non-convex) one in a number of iterative loops until the collision probability constraints are satisfied. IA is shown to converge quickly to a suitable solution. Furthermore, by using a control parameter, the system designer can make a tradeoff between the speed of convergence and the ergodic sum capacity. AA, on the other hand, solves the RA problem by suggesting tractable versions of collision probability constraints. Unlike IA, AA does not require extra signaling between transmitters and the base station to tune parameters, thus facilitating the implementation of SS. Our in-depth simulations have shown the proposed approach to yield lower spectral efficiency than IA.
Hypomethylating agents for patients with myelodysplastic syndrome (2016)

Authors have made no progress with this protocol in two years. New authors are being sought to take over this protocol.