gebhart/patrepeval huggingface dataset:
DEVELOPMENT AND APPLICATION OF ORGANIC SURFACE PREPARATION MATERIALS FOR EXTERIOR WALL TILING WITH ORGANIC ADHESIVES (2017)

Exterior wall tiling using organic adhesives is expected to prevent tiles from separation because of its high elasticity, but generally mortar with poor elasticity has been used to smoothen irregularities of the concrete surface. We have developed an organic surface preparation material with higher elasticity than mortar, so that the tile layer could consist of all elastic materials. Various tests were carried out to evaluate mechanical properties and durability of the surface preparation material and the tiles adhered using this method. Test results showed that the material had enough strength and elasticity to meet JIS A 5557 criterion value. Test results also proved that the tiling had adequate deformational and fatigue property to improve the separation prevention performance.
Transformed hidden Markov models: estimating mixture models of images and inferring spatial transformations in video sequences (2002)

In this paper we describe a novel generative model for video analysis called the transformed hidden Markov model (THMM). The video sequence is modeled as a set of frames generated by transforming a small number of class images that summarize the sequence. For each frame, the transformation and the class are discrete latent variables that depend on the previous class and transformation in the sequence. The set of possible transformations is defined in advance, and it can include a variety of transformation such as translation, rotation and shearing. In each stage of such a Markov model, a new frame is generated from a transformed Gaussian distribution based on the class/transformation combination generated by the Markov chain. This model can be viewed as an extension of a transformed mixture of Gaussians through time. We use this model to cluster unlabeled video segments and form a video summary in an unsupervised fashion. We also use the trained models to perform tracking, image stabilization and filtering. We demonstrate that the THMM is capable of combining long term dependencies in video sequences (repeating similar frames in remote parts of the sequence) with short term dependencies (such as short term image frame similarities and motion patterns) to better summarize and process a video sequence even in the presence of high levels of white or structured noise (such as foreground occlusion).
Studies on DNA-cleaving agents: synthesis of a functional dynemicin analogue (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStudies on DNA-cleaving agents: synthesis of a functional dynemicin analoguePaul A. Wender and Charles K. ZercherCite this: J. Am. Chem. Soc. 1991, 113, 6, 2311–2313Publication Date (Print):March 1, 1991Publication History Published online1 May 2002Published inissue 1 March 1991https://doi.org/10.1021/ja00006a065RIGHTS & PERMISSIONSArticle Views371Altmetric-Citations69LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (459 KB) Get e-AlertsSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Erratum to: Therapeutic Effects of Probiotics in Patients with Atopic Dermatitis (2014)

Jun Hee Yim , Duk Han Kim , Ja Kyung Ku , Yoonsung Kang , Mi-yeon Kim , Hyung Ok Kim , Myung-jun Chung and Young Min Park . J. Microbiol. Biotechnol. 2014;24:295. https://doi.org/10.4014/jmb.2014.24.2.295
MaGNET: Uniform Sampling from Deep Generative Network Manifolds Without\n Retraining (2021)

Deep Generative Networks (DGNs) are extensively employed in Generative\nAdversarial Networks (GANs), Variational Autoencoders (VAEs), and their\nvariants to approximate the data manifold and distribution. However, training\nsamples are often distributed in a non-uniform fashion on the manifold, due to\ncosts or convenience of collection. For example, the CelebA dataset contains a\nlarge fraction of smiling faces. These inconsistencies will be reproduced when\nsampling from the trained DGN, which is not always preferred, e.g., for\nfairness or data augmentation. In response, we develop MaGNET, a novel and\ntheoretically motivated latent space sampler for any pre-trained DGN, that\nproduces samples uniformly distributed on the learned manifold. We perform a\nrange of experiments on various datasets and DGNs, e.g., for the\nstate-of-the-art StyleGAN2 trained on FFHQ dataset, uniform sampling via MaGNET\nincreases distribution precision and recall by 4.1\\% \\&amp; 3.0\\% and decreases\ngender bias by 41.2\\%, without requiring labels or retraining. As uniform\ndistribution does not imply uniform semantic distribution, we also explore\nseparately how semantic attributes of generated samples vary under MaGNET\nsampling.\n
Aberrant cell cycle reentry in human and experimental inclusion body myositis and polymyositis (2014)

Inclusion body myositis (IBM), a degenerative and inflammatory disorder of skeletal muscle, and Alzheimer's disease share protein derangements and attrition of postmitotic cells. Overexpression of cyclins and proliferating cell nuclear antigen (PCNA) and evidence for DNA replication is reported in Alzheimer's disease brain, possibly contributing to neuronal death. It is unknown whether aberrant cell cycle reentry also occurs in IBM. We examined cell cycle markers in IBM compared with normal control, polymyositis (PM) and non-inflammatory dystrophy sample sets. Next, we tested for evidence of reentry and DNA synthesis in C2C12 myotubes induced to express β-amyloid (Aβ42). We observed increased levels of Ki-67, PCNA and cyclins E/D1 in IBM compared with normals and non-inflammatory conditions. Interestingly, PM samples displayed similar increases. Satellite cell markers did not correlate with Ki-67-affected myofiber nuclei. DNA synthesis and cell cycle markers were induced in Aβ-bearing myotubes. Cell cycle marker and cyclin protein expressions were also induced in an experimental allergic myositis-like model of PM in mice. Levels of p21 (Cip1/WAF1), a cyclin-dependent kinase inhibitor, were decreased in affected myotubes. However, overexpression of p21 did not rescue cells from Aβ-induced toxicity. This is the first report of cell cycle reentry in human myositis. The absence of rescue and evidence for reentry in separate models of myodegeneration and inflammation suggest that new DNA synthesis may be a reactive response to either or both stressors.
ChemInform Abstract: Chemistry of Organosilicon Compounds. Part 385. Intramolecular Dimerization of Silylenes Leading to Novel Cyclic Disilenes. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Antibiotic Usage Reduced Overall Survival by over 70% in Non-small Cell Lung Cancer Patients on Anti-PD-1 Immunotherapy (2021)

Use of antibiotics within 21 days before and after anti-PD-1 treatment initiation in patients with NSCLC strongly reduced OS and PFS, suggesting the two treatments should not be combined.
In-situ measurement of VUV optical materials under F 2 laser irradiation (2002)

The 157nm molecular fluorine laser is regarded as the next generation light source for semiconductor exposure technology in the vacuum ultraviolet (VUV) region. Research for high performance F<SUB>2</SUB> laser optical materials is therefore indispensable. In this paper, we describe methods and results of evaluating optical materials used in the 157nm region. In order to evaluate F<SUB>2</SUB> laser optical materials, we have developed in-situ system, which measures the real-time transmittance at 157nm during laser irradiation and the transmittance in the vacuum ultraviolet (VUV) region directly after laser irradiation to avoid airborne contamination. The system is purged with high purity nitrogen gas during irradiation to reduce laser light absorption and to keep contamination at a minimum. Due to F<SUB>2</SUB> laser irradiation cleaning, the transmittance of uncoated calcium fluoride (CaF<SUB>2</SUB>) samples initially rapidly then gradually increased during 50 million pulses (Mpls). Thereafter the transmittance remained constant. In addition, durability test results of CaF<SUB>2</SUB> substrates and coatings are also presented. Especially coating quality varied enormously between suppliers.
P3‐085: Amnestic mild cognitive impairment in a memory clinic: Longitudinal course and predictors of progression (2012)

We wished to examine the long-term natural history of Mild Cognitive Impairment (MCI) in a North American memory clinic, and evaluate differences between those who progress to dementia, and those who do not. Eighty-nine elderly subjects (mean age 74.8 years) referred to a teaching hospital memory clinic and meeting criteria for Amnestic MCI (with or without added cognitive deficits), were followed longitudinally at least 10 years since symptom onset. All received detailed clinical, neuropsychological and genetic assessments, including a detailed evaluation of time of onset of symptoms and MRI volumetrics (in half the cohort). At end of a 10 year follow-up period, 60 subjects had deteriorated to dementia, and 29 had not. Kaplan-Meier curve analysis indicated an s-shaped curve of progression, with a “decline to dementia” rate initially of about 15% of the subjects per year, tapering off after four years. Even up to 10 years after onset of symptoms, 25% of the cohort remained non-demented. Presence or absence of Apo-E4 genotype had minimal impact on progression to dementia over follow-up. Medial temporal lobe atrophy was present in significantly more progressors (56%) compared with non-progressors (7%). Progressors had significantly older age of symptom onset, along with worse delayed verbal memory performance (logical memory). Non-progressors did not have more co-morbidities than progressors. MCI in the memory clinic appears heterogeneous but is sometimes a stable diagnosis over the long term. There appears to be a clear clinical subgroup of ¼ of the subjects who will not deteriorate to dementia over long-term follow-up. Atrophy on MRI was specific, but not sensitive for progression to dementia.
An Inductively Powered Wireless Solid-State Drive System With Merged Error Correction of High-Speed Wireless Data Links and NAND Flash Memories (2016)

A highly reliable wireless solid-state drive (SSD) system for future applications of large volume storage is presented. The wireless interface in the system consists of an inductively coupled power link with fast transmission power control and high-speed data links using transmission line couplers (TLCs). The wireless power link can deliver 1 W from the host to the SSD. The full duplex wireless data interface achieves raw data rate of 1.6 Gb/s. The reliability of the wireless interface is studied though simulation analysis and experiments. The error correction block for the NAND flash memory system can also correct errors in the wireless data links, allowing the requirements for the PHY layer to be relaxed. The error correction code is discussed, including optimization by analyzing the error bits on the wireless data links. The experimental results confirmed strong tolerance to the interference from the power link on the wireless data link, and the water proof property of both the data and power links.
High-Throughput, High-Multiplex Digital Protein Detection with Attomolar Sensitivity (2022)

A major challenge in many clinical diagnostic applications is the measurement of low-abundance proteins and other biomolecules in biological fluids. Digital technologies such as the digital enzyme-linked immunosorbent assay (ELISA) have enabled 1000-fold increases in sensitivity over conventional protein detection methods. However, current digital ELISA technologies still possess insufficient sensitivities for many rare protein biomarkers and require specialized instrumentation or time-consuming workflows that have limited their widespread implementation. To address these challenges, we have developed a more sensitive and streamlined digital ELISA platform, Molecular On-bead Signal Amplification for Individual Counting (MOSAIC), which attains low attomolar limits of detection, with an order of magnitude enhancement in sensitivity over these other methods. MOSAIC uses a rapid, automatable flow cytometric readout that vastly increases throughput and is easily integrated into existing laboratory infrastructure. As MOSAIC provides high sampling efficiencies for rare target molecules, assay bead number can readily be tuned to enhance signal-to-background with high measurement precision. Furthermore, the solution-based signal readout of MOSAIC expands the number of analytes that can simultaneously be measured for higher-order multiplexing with femtomolar sensitivities or below, compared with microwell- or droplet-based digital methods. As a proof of principle, we apply MOSAIC toward improving the detectability of low-abundance cytokines in saliva and ultrasensitive multiplexed measurements of eight protein analytes in plasma and saliva. The attomolar sensitivity, high throughput, and broad multiplexing abilities of MOSAIC provide highly accessible and versatile ultrasensitive capabilities that can potentially accelerate protein biomarker discovery and diagnostic testing for diverse disease applications.
Data from Combining Oncolytic HSV-1 with Immunogenic Cell Death-Inducing Drug Mitoxantrone Breaks Cancer Immune Tolerance and Improves Therapeutic Efficacy (2023)

&lt;div&gt;Abstract&lt;p&gt;Although antitumor activity of herpes simplex virus 1 (HSV-1) &lt;i&gt;ICP0&lt;/i&gt; null oncolytic vectors has been validated in murine breast cancer models, oncolytic virus treatment alone is insufficient to break immune tolerance. Thus, we investigated enhancing efficacy through combination therapy with the immunogenic cell death–inducing chemotherapeutic drug, mitoxantrone. Despite a lack of enhanced cytotoxicity &lt;i&gt;in vitro&lt;/i&gt;, HSV-1 &lt;i&gt;ICP0&lt;/i&gt; null oncolytic virus KM100 with 5 μmol/L mitoxantrone provided significant survival benefit to BALB/c mice bearing Her2/neu TUBO-derived tumors. This protection was mediated by increased intratumoral infiltration of neutrophils and tumor antigen-specific CD8&lt;sup&gt;+&lt;/sup&gt; T cells. Depletion studies verified that CD8-, CD4-, and Ly6G-expressing cells are essential for enhanced efficacy of the combination therapy. Moreover, the addition of mitoxantrone to KM100 oncolytic virus treatment broke immune tolerance in BALB-&lt;i&gt;neu&lt;/i&gt;T mice bearing TUBO-derived tumors. This study suggests that oncolytic viruses in combination with immunogenic cell death–inducing chemotherapeutics enhance the immunogenicity of the tumor-associated antigens, breaking immunologic tolerance established toward these antigens. &lt;i&gt;Cancer Immunol Res; 1(5); 309–19. ©2013 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Carboxymethyl cellulose/poloxamer Gels Enriched With Essential Oil and Ag Nanoparticles: Promising Wound Dressings (2023)

<b>Aim:</b> Essential oils are promising antibacterial and wound-healing agents that should be explored for the design of wound dressings. <b>Materials & methods:</b> Topical gels prepared from a combination of carboxymethyl cellulose and poloxamer were incorporated with tea tree and lavender oil together with Ag nanoparticles. <i>In vitro</i> release, cytotoxicity, antibacterial, and wound healing studies were performed. <b>Results:</b> The gels displayed good spreadability with viscosity in the range of 210-1200 cP. The gels displayed promising antibacterial activity against selected Gram-positive and Gram-negative bacteria used in the study. The % cell viability of the gels was more than 90.83%. <b>Conclusion:</b> The topical gels displayed excellent wound closure <i>in vitro</i> revealing that they are potential wound dressings for bacteria-infected wounds.
Detection of bcl-1 Gene Rearrangement and B-cell Clonality in Mantle Cell Lymphoma Using Formalin-Fixed, Paraffin-Embedded Tissues (1995)

Mantle cell lymphoma (MCL) has recently emerged as a distinct clinicopathologic entity with characteristic molecular genetic features. Specifically, MCL are clonal B-cell neoplasms and often harbor bcl-1 gene rearrangements. Although this genetic profile is well documented, scant or no data are available on the molecular assessment of MCL using formalin-fixed, paraffin-embedded tissue as a sample source. The polymerase chain reaction (PCR) was employed to study bcl-1 and immunoglobulin heavy chain (IgH) gene rearrangements (B-cell clonality) using formalin-fixed tissue from 12 cases of MCL. In addition, 12 cases of low grade B-cell lymphoma and 5 cases of reactive lymphocytic hyperplasia were studied as comparison controls. A hemi-nested PCR assay was developed to identify major translocation cluster (MTC) bcl-1 gene rearrangements, whereas IgH gene rearrangements were evaluated by both a single-step and hemi-nested approach. Bcl-1 gene rearrangements were amplified in 4 of 12 (33%) MCL, but in none of the controls. With the hemi-nested approach, B-cell monoclonality was demonstrated in 11 of 12 (92%) MCL; 6 of 6 (100%) small lymphocytic lymphomas; 1 of 2 marginal zone lymphomas; 1 of 4 follicular lymphomas; and 0 of 5 reactive lymphocytic hyperplasias. When one-step PCR was used for B-cell clonality assessment, the overall detection rate was lower, specifically: 8 of 12 (67%) MCL; 4 of 6 (67%) small lymphocytic lymphomas; 1 of 2 marginal zone lymphomas; 0 of 4 follicular lymphomas; and 0 of 5 reactive lymphocytic hyperplasias were identified as monoclonal. We have demonstrated that MTC bcl-1 gene rearrangements can be amplified from formalin-fixed tissue. In addition, monoclonal B-cell populations from MCL are better amplified with a hemi-nested approach rather than a single-step PCR assay. With specialized nucleic acid isolation techniques and appropriate PCR protocol design, formalin-fixed, paraffin-embedded tissue is an adequate source of DNA for assessing MTC bcl-1 and IgH gene rearrangements.
Atrial Flutter in a Patient Post Fontan (2008)

This chapter contains sections titled: Clinical vignette Electrophysiology study and ablation
ChemInform Abstract: ELEKTRONENSTRUKTUREN VON ARSINEN UND PHOSPHINEN (1972)

Abstract Elektronenspektren des Arsins (I) sowie die der Charge‐transfer‐Komplexe zwischen (I), (II) und (III) als Donatoren und dem Akzeptor Tetracyanäthylen werden gemessen; die letzteren dienen zur Bestimmung der relativen Ionisationspotentiale der Donatoren.
Power Law Liquid - A Unified Form of Low-Energy Nodal Electronic Interactions in Hole Doped Cuprate Superconductors (2016)

The strange-metal phase of the cuprate high temperature superconductors, above where the superconductivity sets in as a function of temperature, is widely considered more exotic and mysterious than the superconductivity itself. Here, based upon detailed angle resolved photoemission spectroscopy measurements of Bi$_2$Sr$_2$CaCu$_2$O$_8$$_+$$_\delta$ over a wide range of doping levels, we present a new unifying phenomenology for the non-Fermi liquid normal-state interactions (scattering rates) in the nodal direction. This new phenomenology has a continuously varying power law exponent (hence named a Power Law Liquid or PLL), which with doping varies smoothly from a quadratic Fermi Liquid to a linear Marginal Fermi Liquid and beyond. Using the extracted PLL parameters we can calculate the optics and resistivity over a wide range of doping and normal-state temperature values, with the results closely matching the experimental curves. This agreement includes the presence of the $$pseudogap$$ temperature scale observed in the resistivity curves including the apparent quantum critical point. This breaks the direct link to the pseudogapping of antinodal spectral weight observed at similar (but here argued to be different) temperature scales, and also gives a new direction for searches of the microscopic mechanism at the heart of these and perhaps many other non-Fermi-liquid systems.
Niobium carbide as an alternative cutting tool material (2016)

Niobium carbide (NbC) is an alternative cutting material. The Federal Institute for Materials Research and Testing (BAM) and the Institute for Machine Tools and Factory Management (IWF) of the TU Berlin assessed the cutting suitability of NbC with cobalt (Co)-binder compared to WC with Co-binder in the machining of a wide range of materials.
Natural occurrence of 3-aryl-4-hydroxycoumarins. Part I. Phytochemical examination of Derris robusta(roxb.) benth. (1969)

The root material of Derris robusta has yielded nine natural products whose structures have been determined mainly by physical methods in association with a few partial syntheses and degradations. Four of these have been shown to be new natural isoflavones: derrustone (II), derrubone (IIIa), robustone (VIa), and robustone methyl ether (VIb). The other five compounds are derivatives of the 3-aryl-4-hydroxycoumarin type, and include derrusnin (VIIb), robustic acid (IXa), robustic acid methyl ether (IXb), robustin (XIIa), and robustin methyl ether (XIIb). These 3-aryl-4-hydroxy(or methoxy)coumarins are variants upon the isoflavonoid theme. The pattern relating the structures of these co-occurring isoflavones and 3-aryl-4-oxycoumarins indicates that the biosyntheses of these two natural product types probably have many common features.
Problems Solving in Electromagnetics, Microwave Circuit and Antenna Design for Communications Engineering (2006)

The Calculus of Differential Forms. Basic Electromagnetics. Potentials and Waves. Concepts, Methods and Theorems. Static and Quasistatic Fields. Waves at the Surface of Conducting Media. Transmission Lines. Resonant Circuits and Resonators. Microwave Circuits. Periodic Structures and Filters. Radiation from Dipoles. Antennas. Numerical Electromagnetics.
Microwave Assisted Synthesis of Thiol Modified Polymethacrylic acid and Its Cross‐Linking with Allyl Modified Polymethacrylic acid via Thiol‐ene “Click” Reaction (2010)

Abstract In this paper, we describe the thiol‐ene “click” reaction with modified poly methacrylic acid in water. The thiol group was implemented by a polymer analogous condensation reaction of polymethacrylic acid ( 1 ) and cysteamine ( 2 ), which was carried out in bulk by use of microwave. The allyl modified polymethacrylic acid ( 5 ) was obtained by DCC‐coupling of the allyl amine onto the polymethacrylic acid backbone. By combination of cysteamine ( 3 ) and allyl modified polymethacrylic acid ( 5 ) the thiol‐ene click reaction could be started with a redox initiator in aqueous solution at room temperature. The kinetics of this reaction were determined by 1 H NMR spectroscopy and the resulting hydrogels were analyzed by rheological measurements and differential scanning calorimetry (DSC). magnified image