gebhart/patrepeval huggingface dataset:
Cathode architectures for alkali metal / oxygen batteries (2023)

Electrochemical energy storage devices, such as alkali metal-oxygen battery cells (e.g., non-aqueous lithium-air cells), have a cathode architecture with a porous structure and pore composition that is tailored to improve cell performance, especially as it pertains to one or more of the discharge/charge rate, cycle life, and delivered ampere-hour capacity. A porous cathode architecture having a pore volume that is derived from pores of varying radii wherein the pore size distribution is tailored as a function of the architecture thickness is one way to achieve one or more of the aforementioned cell performance improvements.
Tuneable fluidics within graphene nanogaps for water purification and energy storage (2017)

Precise control of liquid-solid interactions within sub-micrometer spaces is critical to maximize the active surface areas in porous materials, yet is challenging because of the limited liquid penetration. Here we discover an effective, dry-climate natural plant-inspired approach to guide water into sub-micrometer graphene microwells (Sub-μGWs) and to tune the transition from the hydrophobic to superhydrophilic states. Dry plasma texturing of Sub-μGWs by graphene 'nano-flaps' which adjust the tilt and density upon controlled liquid evaporation leads to controlled and stable sub-micrometer-scale surface modification and variable wettability in a wide range. This effect helps capture Au nanoparticles on the Sub-μGW surfaces as a proof-of-principle water purification platform and tune the charge-storage capacity and frequency response of Sub-μGW-based supercapacitors without altering the Sub-μGW backbones. The outcomes may be extended into diverse materials and solutions thus opening new opportunities for next-generation devices, systems and applications.
New Materials for Liquid Crystal Displays: Structure–Property Relationship of 2‐Fluoropyridines (1994)

The synergy of theory and experiment also works for liquid crystals. Relatively simple calculations offer explanations for the unexpected effect of an alkoxy terminus on the dipole moment of liquid crystal molecules such as 1 and point the way to efficient syntheses of new materials with highly attractive properties for LCD technology.
Practical Watermarking Method Estimating Watermarked Region from Recaptured Videos on Smartphone (2016)

In these days, we can see digital signages in many places, for example, inside stations or trains with the distribution of attractive promotional video clips. Users can easily get additional information related to such video clips via mobile devices such as smartphone by using some websites for retrieval. However, such retrieval is time-consuming and sometimes leads users to incorrect information. Therefore, it is desirable that the additional information can be directly obtained from the video clips. We implement a suitable digital watermarking method on smartphone to extract watermarks from video clips on signages in real-time. The experimental results show that the proposed method correctly extracts watermarks in a second on smartphone.
Immunisation of woodchucks with hepatitis delta antigen expressed by recombinant vaccinia and baculoviruses, controls HDV superinfection. (1993)

We report the investigation of the role of humoral and cell mediated immune responses on hepatitis delta virus (HDV) superinfection of woodchucks chronically infected with woodchuck hepatitis virus (WHV). The animals were immunised with baculovirus or vaccinia virus recombinant hepatitis delta antigen (HDAg) but none showed detectable anti-HD titres prior to challenge with HDV. Following infection, both immunised and control animals developed HD-antigenaemia first detected after 2-3 weeks and lasting for up to 8 weeks. In spite of the presence of HDAg, in immunised animals HDV-RNA could only be detected by nested PCR in contrast with the controls, which were positive by dot blot hybridisation. No serum HDAg or HDV-RNA was detected after the acute episode over the six month follow-up period but intrahepatic HDAg was reported in post-mortem biopsies carried out at six months. Our results demonstrate that immunisation of woodchucks with HDAg expressed by vaccinia or baculovirus does not elicit a humoral immune response. The finding of a marked antigenaemia in the absence of serum HDV-RNA indicates a significant reduction in the number of circulating infectious virions possibly due to a cytotoxic T-cell response.
ESSTCP: Enhanced Spread-Spectrum TCP (2007)

Having stealth and lightweight authentication methods is empowering network administrators to shelter critical services from adversaries. Spread-spectrum TCP (SSTCP) is one of these methods by which the client sends an authentic sequence of SYN packets to the server for authentication. Since SSTCP have some certain drawbacks and security flaws, we propose an enhanced version of SSTCP (ESSTCP) which modifies the original algorithm to reduce the computational cost and cover its vulnerabilities from denial of service and replay attacks. Some performance problems like time synchronization are also resolved. We finally try to extend the functionality of this method for different applications and numbers of users by which ESSTCP can be performed as a secure remote procedure call (RPC).
Correction: Identification of a serum-induced transcriptional signature associated with metastatic cervical cancer (2018)

[This corrects the article DOI: 10.1371/journal.pone.0181242.].
Toward Three-Dimensional High Density (2018)

Below 10 µm pitch of chip-to-chip interconnection, two complementary 3D solutions are taking over: a back-end-of-line (BEOL)-type technology, based on Cu/SiO2 direct hybrid bonding in the range of a few micrometers of pitch; and da front-end-of-line (FEOL)-type technology, named CoolCube™ at CEA-Leti, in the range of few tens of nanometers of pitch. The basis of these principles, process integration, challenges, and perspectives are described in this chapter. Besides, whatever the integration, 3D high density is coming with new and common challenges, among which thermal dissipation. Last paragraph of this chapter dedicated to 3D high-density integration will focus on thermal simulation.
IDDF2023-ABS-0171 Prospective evaluation of a fast-track treatment pathway for patients with chronic hepatitis B under primary care (2023)

<h3>Background</h3> Linkage-to-care is a key gap underlying the suboptimal antiviral treatment uptake. We aimed to develop a novel fast-track treatment pathway for patients with chronic hepatitis B (CHB) under primary care and evaluate its effect on treatment uptake. <h3>Methods</h3> This is a retrospective-prospective longitudinal cohort study. In the prospective cohort, CHB patients under primary care were offered access to transient elastography, serum hepatitis B virus (HBV) DNA and liver biochemistry tests. Those who fulfilled antiviral treatment criteria according to the latest Asian Pacific guidelines were referred to the hepatitis specialist clinic in a protocol-driven, fast-track manner while the rest remained at primary care receiving regular blood tests and transient elastography, and would be referred if the treatment criterion was fulfilled. CHB patients under primary care over three years before served as controls for retrospective analysis. The linkage-to-care, including referral rate to hepatitis specialist clinic, antiviral treatment rate, unnecessary referral, and default rate were analysed. <h3>Results</h3> 502 CHB patients were recruited for prospective analysis after excluding 165 patients with missing or negative hepatitis B surface antigen (HBsAg) and concurrent hepatitis specialist clinic follow-up. 41% of patients were male with a mean age of 62 years. Two percent of patients were positive for hepatitis B e antigen (HBeAg). The baseline mean serum alanine transaminase (ALT) was 29 U/L and the mean serum HBV DNA was 2.7 log<sub>10</sub> IU/mL. The mean liver stiffness measurement (LSM) was 5.6 kPa. (IDDF 2023-ABS-0171 Table 1). 216 (43%) of the patients defaulted on the scheduled HBV workup. Five (1%) patients fulfilled antiviral treatment criteria and were referred to a hepatitis specialist clinic via the fast-track care pathway, which all attended and were started on the oral antiviral agent. <h3>Conclusions</h3> A fast-track treatment pathway provides timely referral of CHB patients under primary care indicated for antiviral treatment. Most patients had inactive CHB without advanced liver fibrosis. A high default rate for HBV workup is an area of concern. This ongoing study will determine whether this pathway can improve the linkage-to-care for CHB patients under primary care.
Multimaterial fiber sensors (2010)

Recent discoveries have enabled the integration of metals, insulators and semiconductors structures into extended length of polymer fibers. This has heralded a novel path and platform towards sensing of different physical quantities such as temperature, chemicals, acoustic waves, and optical signals. The challenges and opportunities associated with this new class of fiber devices will be presented. In particular, we will discuss the materials and fabrication approach of multimaterial fibers. We will then present the latest results on photodetecting fiber sensors patterning to their performance and use in novel sensing designs. We will also introduce the recent development of active fiber devices that integrate a thin ferroelectric polymer layer for acoustic sensing applications. Finally, some aspects of the coming innovation and future prospect of the multimaterial fiber sensing technology will be discussed.
Kinetic Study of the Polymerization of Alkyl Vinyl Ethers by HI/12Catalyst (1988)

Abstract The polymerization of alkyl vinyl ethers initiated by hydrogen iodide and iodine catalyst has been studied in detail. The polymerization showed living behavior in nonpolar solvents at low (-15°) temperatures as reported earlier by others. The observed rate of polymerization under the reaction conditions was linearly dependent on the initial concentration of hydrogen iodide and iodine, respectively. However, the monomer concentration did not influence the rate of polymerization (apparent zero order). From the observed rate equation, two possible reaction schemes were proposed and attempts were made to distinguish them by using UV/visible spectroscopy and 13 C-NMR spectroscopy. In both schemes a reversible interaction between monomer and an iodine molecule was postulated as a necessary elemental reaction to fit the observed expression for rate of polymerization. From the spectroscopic analysis results, the interaction between the iodide compound (chain end) and the iodine molecule seems to be very weak compared to the interaction between monomer and the iodine molecule.
Wireless DC voltage transmission using inductive-coupling channelfor highly-parallel wafer-level testing (2009)

The cost for screening test on wafer has continually increased each year; the test cost especially for low-price IC chips, for example, exceeds one-third of total chip cost. Furthermore, screening test on wafer to select good dies (Known- Good-Die) will become more significant to improve the yields of up-to-date packages such as Chip-on-Chip and 3D-LSI. Therefore, the cost reduction for screening test will be a key issue to maintain continuous LSI-performance scaling. This paper proposes a novel wireless DC voltage transmission technique which implements all the circuits for DC tests into the area of an inductor. There are two keys to this technique. The first one is a wireless DC voltage transceiver that can output DC voltage without any area- consuming circuits on the DUT-chip. The second one is a TX-rich digital calibration method that can correct the error of the DC voltage output without area-consuming calibration circuits on the DUT-chip.
ChemInform Abstract: Anhydrous Tetramethylammonium Fluoride for Room‐Temperature SNAr Fluorination. (2016)

Abstract Optimized conditions are elaborated in detail for the title process and NMe 4 F is found to be generally more cost‐effective than CsF.
An R package suite for microarray meta-analysis in quality control, differentially expressed gene analysis and pathway enrichment detection (2012)

Supplementary data are available at Bioinformatics online.
An SECM‐Based Spot Analysis for Redoxmer‐Electrode Kinetics: Identifying Redox Asymmetries on Model Graphitic Carbon Interfaces (2022)

The fundamental process in non-aqueous redox flow battery (NRFB) operation revolves around electron transfer (ET) between a current collector electrode and redox-active organic molecules (redoxmers) in solution. Here, we present an approach utilizing scanning electrochemical microscopy (SECM) to evaluate interfacial ET kinetics between redoxmers and various electrode materials of interest at desired locations. This spot-analysis method relies on the measurement of heterogeneous electron transfer rate constants (k<sub>f</sub> or k<sub>b</sub> ) as a function of applied potential (E-E<sup>0</sup> '). As demonstrated by COMSOL simulations, this method enables the quantification of Butler-Volmer kinetic parameters, the standard heterogeneous rate constant, k<sup>0</sup> , and the transfer coefficient, α. Our method enabled the identification of inherent asymmetries in the ET kinetics arising during the reduction of ferrocene-based redoxmers, compared to their oxidation which displayed faster rate constants. Similar behavior was observed on a wide variety of carbon electrodes such as multi-layer graphene, highly ordered pyrolytic graphite, glassy carbon, and chemical vapor deposition-grown graphite films. However, aqueous systems and Pt do not exhibit such kinetic effects. Our analysis suggests that differential adsorption of the redoxmers is insufficient to account for our observations. Displaying a greater versatility than conventional electroanalytical methods, we demonstrate the operation of our spot analysis at concentrations up to 100 mM of redoxmer over graphite films. Looking forward, our method can be used to assess non-idealities in a variety of redoxmer/electrode/solvent systems with quantitative evaluation of kinetics for applications in redox-flow battery research.
Characterization and understanding of performance losses in a highly efficient solution-processed CZTSSe thin-film solar cell (2012)

We present results on the characterization of a highly efficient CZTSSe solar cell fabricated using a solution-based process, aiming to gain a better understanding of its efficiency-limiting causes. Under red light illumination, we observed a red-kink in the current-density versus voltage (J-V) curve, likely due to a persistent photoconductivity in the buffer layer. Temperature-dependent J-V analysis suggests that interface recombination is the dominant loss mechanism. Defect analysis using admittance spectroscopy (AS) shows a single bulk defect level at ∼63 meV and may be attributed to copper vacancy (V <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Cu</inf> ). The carrier concentration of the device determined using drive-level capacitance profiling (DLCP) is ∼2.5×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">16</sup> cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−3</sup> .
Phase I/II trial of vorinostat combined with temozolomide and radiation therapy for newly diagnosed glioblastoma: results of Alliance N0874/ABTC 02 (2017)

Vorinostat, a histone deacetylase (HDAC) inhibitor, has shown radiosensitizing properties in preclinical studies. This open-label, single-arm trial evaluated the maximum tolerated dose (MTD; phase I) and efficacy (phase II) of vorinostat combined with standard chemoradiation in newly diagnosed glioblastoma. Patients received oral vorinostat (300 or 400 mg/day) on days 1–5 weekly during temozolomide chemoradiation. Following a 4- to 6-week rest, patients received up to 12 cycles of standard adjuvant temozolomide and vorinostat (400 mg/day) on days 1–7 and 15–21 of each 28-day cycle. Association between vorinostat response signatures and progression-free survival (PFS) and overall survival (OS) was assessed based on RNA sequencing of baseline tumor tissue. Phase I and phase II enrolled 15 and 107 patients, respectively. The combination therapy MTD was vorinostat 300 mg/day and temozolomide 75 mg/m2/day. Dose-limiting toxicities were grade 4 neutropenia and thrombocytopenia and grade 3 aspartate aminotransferase elevation, hyperglycemia, fatigue, and wound dehiscence. The primary efficacy endpoint in the phase II cohort, OS rate at 15 months, was 55.1% (median OS 16.1 mo), and consequently, the study did not meet its efficacy objective. Most common treatment-related grade 3/4 toxicities in the phase II component were lymphopenia (32.7%), thrombocytopenia (28.0%), and neutropenia (21.5%). RNA expression profiling of baseline tumors (N = 76) demonstrated that vorinostat resistance (sig-79) and sensitivity (sig-139) signatures had a reverse and positive association with OS/PFS, respectively. Vorinostat combined with standard chemoradiation had acceptable tolerability in newly diagnosed glioblastoma. Although the primary efficacy endpoint was not met, vorinostat sensitivity and resistance signatures could facilitate patient selection in future trials.
Induction of apoptosis by Dae-Hwang-Mok-Dan-Tang in HCT-116 colon cancer cells through activation of caspases and inactivation of the phosphatidylinositol 3-kinase/Akt signaling (2017)

Our data showed that DHMDT induces HCT-116 cell apoptosis by activating intrinsic and extrinsic apoptosis pathways and by suppressing the PI3K/Akt signal pathway; however, further studies are needed to identify the active compounds.
Noninvasive Optical Detection of Bone Mineral (2007)

FRFP may function as a local biomarker of bisphosphonate deposition to assess interplay between drug and cellular environment or may be combined with other imaging agents or fluorescent cells for the noninvasive assessment of local bone metabolism in vivo.
Optimized Decoding-Energy-Aware Encoding in Practical VVC Implementations (2022)

The optimization of the energy demand is crucial for modern video codecs. Previous studies show that the energy demand of VVC decoders can be improved by more than 50% if specific coding tools are disabled in the encoder. However, those approaches increase the bit rate by over 20% if the concept is applied to practical encoder implementations such as VVenC. Therefore, in this work, we investigate VVenC and study possibilities to reduce the additional bit rate, while still achieving low-energy decoding at reasonable encoding times. We show that encoding using our proposed coding tool profiles, the decoding energy efficiency is improved by over 25% with a bit rate increase of less than 5% with respect to standard encoding. Furthermore, we propose a second coding tool profile targeting maximum energy savings, which achieves 34% of energy savings at bitrate increases below 15%.
Treatment of acute leukemia in relapse with 4'(9-acridinylamino) methanesulfon-m-anisidide (AMSA) in combination with cytosine arabinoside and thioguanine. (1981)

Thirty-seven patients with acute leukemia in relapse were treated with a three-drug combination that included a 3- or 4-day course of AMSA with total doses ranging from 600 mg/m2 to 740 mg/m2 I.V., cytosine arabinoside 25 mg/m2 I.V. followed by 200 mg/m2 by continuous infusion daily for 5 days, and thioguanine 100 mg/m2 p.o. q 12h for 5 days. Eight of the 25 patients with acute nonlymphoblastic leukemia achieved a complete remission and 3 a partial remission. None of the five patients with acute lymphoblastic leukemia achieved a response and there was one partial remission in the seven patients with myelodysplastic syndrome or blastic CML. Reversible toxicity included nausea and vomiting (78%), alopecia (100%), pancytopenia (100%), mild stomatitis (63%), and hepatic dysfunction (24%). One patient developed seizures and cardiac arrhythmias. The activity of this combination in heavily treated patients with ANLL is comparable to that of the anthracycline-containing regimens, and its use in previously untreated patients with ANLL should now be explored.
Pulmonary gallium-67 uptake in amiodarone pneumonitis. (1984)

Three patients are presented suffering from interstitial pneumonitis caused by amiodarone. Pulmonary Ga-67 uptake occurred in all three. There appeared to be a discrepancy between the scintigraphic and radiographic findings in two patients. Gallium-67 lung scintigraphy may offer an early, sensitive indicator for amiodarone pneumonitis.
Expression of hsv1-miR-H18 and hsv2-miR-H9 as a field defect marker for detecting prostate cancer (2021)

The viral miRNAs hsv1-miR-H18 and hsv2-miR-H9 may be associated with field cancerization of PCa and could be promising supplemental biomarkers to the PSA assay to decrease the rate of unnecessary biopsy, particularly in patients within the PSA gray zone.
Crystal chemistry and mechanism in the high-Tc copper oxides (1991)

Several structural, normal‐state, and superconductive properties of the high‐Tc copper oxides are discussed as a prelude to the proposal of a correlation‐bag model of Cooper‐pair formation. All copper oxides have intergrowth structures, which introduce not only anisotropy—both electronic and mechanical—but also internal electric fields normal to the intergrowths in addition to the local electric fields at copper due to the oxygen coordination. The significance of these internal fields for the oxidation state of the superconductive CuO2 layers is illustrated, and the need for all Cu of a CuO2 layer to have the same oxygen coordination is emphasized. The role of interlayer bond‐length mismatch is illustrated by the A2CuO4 compounds. Evidence for a first‐order phase change on going from the antiferromagnetic‐semiconductor to the superconductor phase is presented, and XPS data indicative of a change from more ionic to more covalent Cu‐3d, O‐2pσ bonding across this phase change is cited. Evidence for intermediate correlation energies (U≳W) in the superconductive phase and an equilibrium reaction Cu3++O2−⇄Cu2++O− near cross‐over are argued to give rise to instabilities that cannot be expressed as a negative‐U charge‐density wave; they therefore give rise to dynamic charge fluctuations that are manifest as spin fluctuations in the hole‐poor regions and as paired holes in the hole‐rich regions. Where the pair density is large enough for pair‐pair interactions, a cooperative condensation into the superconductive state occurs. Pair formation is stabilized not only by the electron‐phonon interactions, but also by modulation of the bandwidth—and hence also the correlation energy—within a charge fluctuation.
Object-independent structural image analysis: History and modern approaches (2014)

This paper discusses the history of the appearance and development of structural image analysis. The characteristic disadvantages and advantages of the structural methods that are used and the prerequisites for improving them are analyzed for each of the historical stages. The material culminates with a description of the features of the organization and possibilities of the optimum modern algorithms for structural analysis and a treatment of directions in which they can be improved further.
Ultra Fast Nonlinear Optical Tuning of Photonic Crystal Cavities (2007)

We demonstrate fast (up to 20 GHz), low power (5 muW) modulation of photonic crystal cavities in GaAs containing InAs quantum dots. Modulation is achieved via free carrier injection by an above-band picosecond laser pulse.