gebhart/patrepeval huggingface dataset:
Highly lytic CD8+, alpha beta T-cell receptor cytotoxic T cells with major histocompatibility complex (MHC) class I antigen-directed cytotoxicity in beta 2-microglobulin, MHC class I-deficient mice. (1993)

Targeted disruption of the beta 2-microglobulin (beta 2m) gene results in major histocompatibility complex (MHC) class I deficiency and virtual disappearance of functional CD8+ cytotoxic T lymphocytes (CTLs) in beta 2m-deficient (beta 2m-/-) mice. We asked whether the beta 2m-/- mice are able to reject tumor cells injected i.p. and what is the cellular composition of peritoneal exudate leukocytes (PELs) from such mice. We found that beta 2m-/- mice do reject MHC class I-bearing tumor cells injected i.p. Surprisingly, analysis of PEL CTLs obtained from i.p. tumor-injected beta 2m -/- mice revealed the presence of a large proportion of functional, tumor-destroying CD8+, CD4-, alpha beta T-cell receptor-positive, CD3+, Thy-1+, MHC class I-negative CTLs with strong MHC class I-directed cytotoxic activity. These results call for careful studies of local accumulation of CD8+ CTLs in beta 2m -/- mouse models and suggest that the dramatic decrease in MHC class I expression caused by beta 2m gene disruption does not prevent CD8+/CD4- cell selection and expansion.
Identification of QTLs controlling aroma volatiles using a ‘Fortune’ x ‘Murcott’ (Citrus reticulata) population (2017)

Some fruit aroma QTLs were identified and the candidate genes in the terpenoid biosynthetic pathway were found within the QTL intervals. These QTLs could lead to an efficient and feasible MAS approach to mandarin flavor improvement.
Laser Mode-locking using SWCNT@BNNT with 1D van der Waals Heterostructure as a Saturable Absorber with a High Optical Damage Threshold (2021)

In ultrafast optics, a single-walled carbon nanotube (SWCNT) is famous for its high reliability serving as a saturable absorber for the generation of ultrashort pulses.
Interference criteria for the focusing of light (1980)

A method is proposed for increasing the effectiveness of an adaptive system for the focusing of light beams traveling in an inhomogeneous nonlinear medium. A case of practical importance, when the target size is greater than a diffraction-limited light spot, is considered. The results of a numerical experiment demonstrate the effectiveness of the method.
Efficient Ordering Calculation Method Using Frequency Correlation for MU-MIMO-OFDM THP (2017)

This paper proposes an efficient ordering calculation method employing frequency correlation in multiuser multiple-input multiple-output orthogonal frequency division multiplexing (MU-MIMO-OFDM) Tomlinson Harashima Precoding (THP). Although the ordering process is effective to improve the transmission performance of THP, it requires a large amount of computational effort due to sub-carrier-based operation. To cope with this problem, the proposed method thins out the sub-carriers conducting the ordering process based on the frequency correlation. The basic idea behind this proposal is that the ordering results are considered to be the same among the neighboring sub-carriers in a relatively small delay spread. Moreover, the frequency correlation is derived from a delay profile which can be determined by multiple transmit antennas. The effectiveness of the proposed method is demonstrated in terms of calculation cost and the bit error rate (BER) by comparing with the traditional MU-MIMO-OFDM THP without thinning.
Evaluation and Selection of Candidate Reference Genes for Normalization of Quantitative RT-PCR in Withania somnifera (L.) Dunal (2015)

Quantitative real-time PCR (qRT-PCR) is now globally used for accurate analysis of transcripts levels in plants. For reliable quantification of transcripts, identification of the best reference genes is a prerequisite in qRT-PCR analysis. Recently, Withania somnifera has attracted lot of attention due to its immense therapeutic potential. At present, biotechnological intervention for the improvement of this plant is being seriously pursued. In this background, it is important to have comprehensive studies on finding suitable reference genes for this high valued medicinal plant. In the present study, 11 candidate genes were evaluated for their expression stability under biotic (fungal disease), abiotic (wounding, salt, drought, heat and cold) stresses, in different plant tissues and in response to various plant growth regulators (methyl jasmonate, salicylic acid, abscisic acid). The data as analyzed by various software packages (geNorm, NormFinder, Bestkeeper and ΔCt method) suggested that cyclophilin (CYP) is a most stable gene under wounding, heat, methyl jasmonate, different tissues and all stress conditions. T-SAND was found to be a best reference gene for salt and salicylic acid (SA) treated samples, while 26S ribosomal RNA (26S), ubiquitin (UBQ) and beta-tubulin (TUB) were the most stably expressed genes under drought, biotic and cold treatment respectively. For abscisic acid (ABA) treated samples 18S-rRNA was found to stably expressed gene. Finally, the relative expression level of the three genes involved in the withanolide biosynthetic pathway was detected to validate the selection of reliable reference genes. The present work will significantly contribute to gene analysis studies in W. somnifera and facilitate in improving the quality of gene expression data in this plant as well as and other related plant species.
Supporting community in third places with situated social software (2009)

The Community Collage (CoCollage) is designed to cultivate community in a café, a quintessential "third place", by bringing the richness of online social software into a physical community space. The system shows photos and quotes uploaded to a web site by café patrons and staff on a large computer display in the café, providing a new channel for awareness, interactions and relationships among people there. We describe the CoCollage system and report on insights and experiences resulting from a 2-month deployment of the system, focusing on the impact the system has had on the sense of community within the café.
Dominant Expression of DCLK1 in Human Pancreatic Cancer Stem Cells Accelerates Tumor Invasion and Metastasis (2016)

Patients with pancreatic cancer typically develop tumor invasion and metastasis in the early stage. These malignant behaviors might be originated from cancer stem cells (CSCs), but the responsible target is less known about invisible CSCs especially for invasion and metastasis. We previously examined the proteasome activity of CSCs and constructed a real-time visualization system for human pancreatic CSCs. In the present study, we found that CSCs were highly metastatic and dominantly localized at the invading tumor margins in a liver metastasis model. Microarray and siRNA screening assays showed that doublecortin-like kinase 1 (DCLK1) was predominantly expressed with histone modification in pancreatic CSCs with invasive and metastatic potential. Overexpression of DCLK1 led to amoeboid morphology, which promotes the migration of pancreatic cancer cells. Knockdown of DCLK1 profoundly suppressed in vivo liver metastasis of pancreatic CSCs. Clinically, DCLK1 was overexpressed in the metastatic tumors in patients with pancreatic cancer. Our studies revealed that DCLK1 is essential for the invasive and metastatic properties of CSCs and may be a promising epigenetic and therapeutic target in human pancreatic cancer.
Enhanced Predictive Control for a Wide Time-Variant Frequency Environment (2016)

The use of power converters has considerably grown up, in part, because refined control strategies have been recently proposed, including nonlinear schemes such as predictive control. This approach is used in this work considering a variable grid frequency environment in order to get an appropriate response for a wide ac mains frequency range. Indeed, in order to achieve appropriate, both dynamic and static, responses for all operating frequencies, the number of samples per period is kept constant and independent of the ac mains frequency. This allows a fixed resolution of the sensed voltages and/or currents, which is preferable if high-performance digital control schemes are required. However, imposing a constant number of samples per period requires a variable sampling time in systems that feature variable ac mains frequency. On the other hand, predictive control has been developed and well documented just for a constant sampling frequency. This work presents how to extend the predictive control algorithms for variable sampling time allowing high-performance waveforms and wider ac mains frequency range. Simulated and experimental results show the feasibility of the proposed control strategy which corroborates the mathematical and model analysis.
Learning-Based Joint Channel Prediction and Antenna Selection for Massive MIMO with Partial CSI (2022)

This paper investigates the massive multi-input multi-output (MIMO) system in practical deployment scenarios, in which, to balance the economic and energy efficiency with the system performance, the number of radio frequency (RF) chains is smaller than the number of antennas. The base station employs antenna selection (AS) to fully harness the spatial multiplexing gain. Conventional AS techniques require full channel state information (CSI), which is time-consuming as the antennas cannot be simultaneously connected to the RF chains during the channel estimation process. To tackle this issue, we propose a novel joint channel prediction and AS (JCPAS) framework to reduce the CSI acquisition time and improve the system performance under temporally correlated channels. Our proposed JCPAS framework is a fully probabilistic model driven by deep unsupervised learning. The proposed framework is able to predict the current full CSI, while requiring only a historical window of partial observations. Extensive simulation results show that the proposed JCPAS can significantly improve the system performance under temporally correlated channels, especially for very large-scale systems with highly correlated channels. multi-output (MIMO) system in practical deployment scenarios, in which, to balance the economic and energy efficiency with the system performance, the number of radio frequency (RF) chains is smaller than the number of antennas. The base station employs antenna selection (AS) to fully harness the spatial multiplexing gain. Conventional AS techniques require full channel state information (CSI), which is time-consuming as the antennas cannot be simultaneously connected to the RF chains during the channel estimation process. To tackle this issue, we propose a novel joint channel prediction and AS (JCPAS) framework to reduce the CSI acquisition time and improve the system performance under temporally correlated channels. Our proposed JCPAS framework is a fully probabilistic model driven by deep unsupervised learning. The proposed framework is able to predict the current full CSI, while requiring only a historical window of partial observations. Extensive simulation results show that the proposed JCPAS can significantly improve the system performance under temporally correlated channels, especially for very large-scale systems with highly correlated channels.
Automated body modeling from video sequences (2003)

Synthetic modeling of human bodies and the simulation of motion is a long-standing problem in animation and much work is involved before a near-realistic performance can be achieved. At present, it takes an experienced designer a very long time to build a complete and realistic model that closely resembles a specific person. Our ultimate goal is to automate the process and to produce realistic animation models given a set of video sequences. In this paper we show that, given video sequences of a person moving in front of the camera, we can recover shape information and joint locations. Both of which are essential to instantiate a complete and realistic model that closely resembles a specific person and without knowledge about the position of the articulations a character cannot be animated. This is achieved with minimal human intervention. The recovered shape and motion parameters can be used to reconstruct the original movement or to allow other animation models to mimic the subject's actions.
13C and 1H NMR studies of structure and tautomerism in some perimidines (1988)

Abstract The 13 C NMR spectra of some 1‐ and 2‐substituted perimidines and perimidinium salts are discussed and assigned. Although the spectra of most of the 2‐substituted perimidines are comparatively simple, several examples display 13 C and 1 H spectral characteristics indicative of inhibition of prototropic tautomerism.
Design of polarization-maintaining retro-reflector for folded-path applications (2011)

A design of polarization-maintaining retro-reflectors (PMRRs) for folded-path applications is proposed and analyzed. The prism-based scheme enables the output light, which is parallel to the input, to have an identical state of polarization. The principle of the design is theoretically verified, and the related error is analyzed due to possible manufacturing imperfection. The maximum spatial angle error is 2.75 . The effect on the extinction ratio and insertion loss is also discussed, which further proves the design's feasibility in practical applications.
Inertial Sensor Algorithm to Estimate Walk Distance (2022)

The "total distance walked" obtained during a standardized walking test is an integral component of physical fitness and health status tracking in a range of consumer and clinical applications. Wearable inertial sensors offer the advantages of providing accurate, objective, and reliable measures of gait while streamlining walk test administration. The aim of this study was to develop an inertial sensor-based algorithm to estimate the total distance walked using older subjects with impaired fasting glucose (Study I), and to test the generalizability of the proposed algorithm in patients with Multiple Sclerosis (Study II). All subjects wore two inertial sensors (Opals by Clario-APDM Wearable Technologies) on their feet. The walking distance algorithm was developed based on 108 older adults in Study I performing a 400 m walk test along a 20 m straight walkway. The validity of the algorithm was tested using a 6-minute walk test (6MWT) in two sub-studies of Study II with different lengths of a walkway, 15 m (Study II-A, <i>n</i> = 24) and 20 m (Study II-B, <i>n</i> = 22), respectively. The start and turn around points were marked with lines on the floor while smaller horizontal lines placed every 1 m served to calculate the manual distance walked (ground truth). The proposed algorithm calculates the forward distance traveled during each step as the change in the horizontal position from each foot-flat period to the subsequent foot-flat period. The total distance walked is then computed as the sum of walk distances for each stride, including turns. The proposed algorithm achieved an average absolute error rate of 1.92% with respect to a fixed 400 m distance for Study I. The same algorithm achieved an absolute error rate of 4.17% and 3.21% with respect to an averaged manual distance for 6MWT in Study II-A and Study II-B, respectively. These results demonstrate the potential of an inertial sensor-based algorithm to estimate a total distance walked with good accuracy with respect to the manual, clinical standard. Further work is needed to test the generalizability of the proposed algorithm with different administrators and populations, as well as larger diverse cohorts.
Effect of Plasma Pretreatment on Thermal Durability of Thermal Barrier Coatings in Cyclic Thermal Exposure (2014)

Plasma pretreatment on the top and bond coats was performed and its influence on the thermal durability of thermal barrier coating (TBC) system was investigated through cyclic thermal exposure. Two types of bond coat were prepared by different methods, namely, air plasma spray (APS) and high-velocity oxy-fuel (HVOF), and two kinds of feedstock powder were employed for preparing the top coat in APS process. The better thermal durability was achieved in the vertically cracked TBC with the surface modified bond coat or with the bond coat prepared by APS process. The hardness and fracture toughness values of TBCs increased because of densification of the top coat during cyclic thermal exposure, and the bond coat prepared by HVOF process showed higher values than that by APS process. The TBCs with the surface modified bond coat were more efficient in improving adhesive strength than those without plasma pretreatment on the bond coat. The relationship between microstructure evolution and thermomechanical characteristics of TBCs with plasma pretreatment was discussed in cyclic thermal exposure.
Surface Acoustic Wave Duplexer for US Personal Communication Services with Good Temperature Characteristics (2005)

The transmission (Tx) and receiving (Rx) passbands of the Personal Communication Services (PCS) mobile phone system in the US are 1850–1910 MHz and 1930–1990 MHz, respectively. The transition bandwidth between Tx and Rx is very narrow, 20 MHz. A duplexer for the US-PCS employing surface acoustic waves (SAWs) requires a substrate which has good temperature stability, an optimum electromechanical coupling factor, a large reflection coefficient, and a good resonant mechanical Q value. Previously, there did not exist any substrate suitable for the US-PCS SAW duplexer. In this paper, we describe a new substrate that is suitable for the US-PCS SAW duplexer and a US-PCS SAW duplexer constructed with this new substrate.
Industrial-Scale Solution Blowing of Soy Protein Nanofibers (2015)

Solution blowing is one of the most industrially viable processes for mass production of nanofibers without significant change of trade practices. In this work a novel industrially scalable approach to nanofiber production by solution blowing is demonstrated using Biax die. Blends of biopolymer soy protein isolate Clarisoy 100 and poly(ethylene oxide) (Mw = 600 kDa) were solution blown as aqueous solutions using a spinneret with 8 rows with 41 concentric annular nozzles. Nanofiber mats were collected on a drum, and samples with an area of the order of 0.1–1 m2 were formed in about 10 s. Nanofibers were relatively uniform with the diameters of about 500–600 nm. Theoretical aspects of capillary instability, dripping, and fly formation in solution blowing relevant from the experimental point of view are discussed, as well as ways of their prevention are revealed.
Transforming epitope-specific gp120 monomer-based probes into immunogens with N-linked glycan masking (2012)

Background HIV-1 gp120 monomer-based probes have been used for the identification of broadly neutralizing antibodies. Such probes could represent starting points in the design of HIV-1 immunogens, though efforts must be made to silence immune responses directed toward non-neutralizing epitopes. One possible approach would be to mask these epitopes by introducing N-linked glycan. A potential complication to such an approach is glycan occupancy: although N-linked glycosylation generally occurs at N-X-T/S sequons, many such sequons are not occupied.
Promotion of V-P Oxide Catalyst for Butane Oxidation by Metal Additives (1992)

Abstract Mixed oxide catalyst V-P-O for the butane oxidation to maleic anhydride was significantly promoted by the addition of some metal cations. In particular, the addition of a small amount of Bi (Bi/V = 0.02) was the most effective. Over the Bi-added catalyst, the MA selectivity exceeded 70 mol% up to the butane conversion level of 88 mol%, attaining the maximum MA yield of 62 mol% at 395 °C.
Search for a Vectorlike Quark with Charge2/3int+ZEvents fromppCollisions ats=7  TeV (2011)

A search for pair-produced heavy vectorlike charge-2/3 quarks, T, in pp collisions at a center-of-mass energy of 7 TeV, is performed with the CMS detector at the LHC. Events consistent with the flavor-changing-neutral-current decay of a T quark to a top quark and a Z boson are selected by requiring two leptons from the Z-boson decay, as well as an additional isolated charged lepton. In a data sample corresponding to an integrated luminosity of 1.14 fb(-1), the number of observed events is found to be consistent with the standard model background prediction. Assuming a branching fraction of 100% for the decay T→tZ, a T quark with a mass less than 475 GeV/c(2) is excluded at the 95% confidence level.
Deletion of plasmid sequences during Saccharomyces cerevisiae transformation (1984)

Saccharomyces cerevisiae was transformed with DNA by the lithium acetate method. Mutation of nonselected markers on the transforming vector was observed at a frequency several orders of magnitude higher than spontaneous mutation frequencies. These mutations were shown to be deletions. Linearization of the vector before transformation stimulated deletion formation.
Glycocinnasperimicin D, a new member of glycocinnamoylspermidine antibiotic. (1985)

Glycocinnasperimicin D was isolated from the fermentation filtrate of a strain of Nocardia sp. using various procedures of column chromatography. Glycocinnasperimicin D exhibited broad antibacterial spectrum. Its chemical structure was determined by NMR spectrometric analyses.
Virtual assistants for mobile interaction (2018)

The technology of virtual assistants (VAs) is a powerful option to support the interaction of human users with computational systems. These VAs are able, for example, to identify interaction problems and offer recommendations on the execution of commands. This work analyses the use of VAs as a resource of accessibility for mobile devices. This analysis was carried out by means of a literature review, which considered both academic studies and commercial solutions. The results showed that there are very few researches in this area and this fact motivated the development of an evaluation protocol, and related set of tests cases, which can verify if current VAs are in fact able to support the interaction of motor and visually impaired users with their mobile devices.
Mechanism of Action for Therapeutic Antibodies (2016)

The complexity of cancer and other diseases calls for the development of multiple antibody (Ab)-based drugs for even a single disease target. In the case of targeting tumor necrosis factor (TNF) for autoimmune diseases, five drugs were developed with different biological activities. Meanwhile, a better understanding of Ab-based mechanisms of action (MOAs) has led to the expansion of pharmaceuticals with increased potency and greater precision. Most of the Ab-based therapeutics for oncological applications target cell surface receptors. The ligand-receptor interaction is the initial step in signaling transduction for a number of cellular events, including cell proliferation, adhesion, and migration. The actions of Abs targeting cell surface receptor are threefold: inhibit receptor signaling by blocking the receptor binding to the ligand; down-regulate the receptor surface display; and engage immune effector functions including antibody-dependent cellular cytotoxicity (ADCC), complement-dependent cytotoxicity (CDC), and antibody-dependent cellular phagocytosis (ADCP).
Measurement of Recrystallization Texture in H.C.P. Structures by the Selected Area Channeling Pattern Method (1991)

The technique to measure recrystallization texture for h.c.p. system by the SACP method is studied theoretically. In addition a SACP standard map covering the entire [0001–1210–1100] triangle is constructed in pure titanium. Based on the map the technique is examined experimentally and good agreement between pole figures measured with the SACP method and X-ray diffraction method is obtained. Es wird die Technik der Rekristallisationstexturmessung für das h.c.p.-System mit der SACP-Methode theoretisch untersucht. Zusätzlich wird eine SACP-Standardkarte, die das gesamte 0001–1210–11001-Dreieck in reinem Titan überdeckt, konstruiert. Auf der Grundlage dieser Karte wird die Technik experimentell überprüft und es wird gute übereinstimmung zwischen den Polfiguren erhalten, die mit der SACP- und der Röntgenbeugungsmethode gemessen werden.