gebhart/patrepeval huggingface dataset:
Economic effects of catalyst deactivation during VOC oxidation (1993)

Abstract Catalytic oxidation of volatile organic compounds (VOCs) is widely used for air pollution control. While catalytic oxidation offers several advantages over alternative processes, the catalyst can deactivate over time, resulting in changes in activity and selectivity with time‐on‐stream. To maintain constant catalyst activity, required for environmental regulations, the temperature is generally increased gradually to compensate for catalyst deactivation. This results in an increase in fuel consumption with time. Since the fuel costs can account for 50 to 70 percent of the total operating costs, the effect of catalyst deactivation on fuel costs and hence total operating costs should be considered. This paper shows how the catalyst deactivation affects the total operating costs using an example of the oxidation of a VOC‐containing gas stream over a commercial hopcalite catalyst.
Synthesis of p-Quinquephenyl from E,E-1,4-Bis(4-bromophenyl)-1,3-butadiene (2010)

p-Quinquephenyl was synthesized in five steps from E,E-1,4-bis(4-bromophenyl)-1,3-butadiene in 34% overall yield. The butadiene was prepared in six steps from 4-bromobenzaldehyde in 35% overall yield.
Supplementary Figure 2 from Angiopoietin-1 Overexpression Modulates Vascular Endothelium to Facilitate Tumor Cell Dissemination and Metastasis Establishment (2023)

Supplementary Figure 2 from Angiopoietin-1 Overexpression Modulates Vascular Endothelium to Facilitate Tumor Cell Dissemination and Metastasis Establishment
Current-Expansion Technique for Characterization of Waveguide Discontinuities of Irregular Shape (1998)

ABSTRACT A current-expansion technique is proposed to analyze the waveguide discontinuities of irregular shape. Roof-top and rectangular-pipe sub-domain functions are used in an electric-field integral-equation formulation to adequately expand the three-dimensional current densities of an irregularly-shaped conductor. It is therefore applicable to quite general discontinuity configurations. Numerical results for a variety of waveguide discontinuities including open-ends, bends, and T junctions have been demonstrated and verified by the available published data.
Network-based Localized IP mobility Management: Proxy Mobile IPv6 and Current Trends in Standardization (2010)

IP mobility support has been a hot topic over the last years, recently fostered by the role of IP in the evolution of the 3G mobile communication networks. Standardization bodies, namely IETF, IEEE and 3GPP are working on different aspects of the mobility aiming at improving the mobility experience perceived by users. Traditional IP mobility support mechanisms, Mobile IPv4 or Mobile IPv6, are based on the operation of the terminal to keep ongoing sessions despite the movement. The current trend is towards network-based solutions where mobility support is based on network operation. Proxy Mobile IPv6 is a promising specification that allows network operators to provide localized mobility support without relying on mobility functionality or configuration present in the mobile nodes, which greatly eases the deployment of the solution. This paper presents ProxyMobile IPv6 and the different extensions that are been considered by the standardization bodies to enhance the basic protocol with interesting features needed to offer a richer mobility experience, namely, flow mobility, multicast and network mobility support. 1
Microwave magnetic field modulation of spin torque oscillator based on perpendicular magnetic tunnel junctions (2019)

Modulation of a spin-torque oscillator (STO) signal based on a magnetic tunnel junction (MTJ) with perpendicularly magnetized free layer is investigated. Magnetic field inductive loop was created during MTJ fabrication process, which enables microwave field application during STO operation. The frequency modulation by the microwave magnetic field of up to 3 GHz is explored, showing a potential for application in high-data-rate communication technologies. Moreover, an inductive loop is used for self-synchronization of the STO signal, which after field-locking exhibits significant improvement of the linewidth and oscillation power.
Safety and Immunogenicity of a 20-valent Pneumococcal Conjugate Vaccine in Healthy Infants in the United States (2021)

Administration of PCV20 in US infants was well tolerated, with a safety profile similar to PCV13, and induced robust serotype-specific immune responses. These findings support continued development of PCV20 in the pediatric population.
ChemInform Abstract: THE REACTION OF ARYL NITRONES WITH THIONYL CHLORIDE OR PHOSGENE (1974)

Abstract 64 Das Diphenylnitron (I) wird mit Thionylchlorid oder Phosgen umgesetzt und hierbei ein Gemisch aus Benzyliden‐2‐ (II) und ‐4‐chlor‐anilin (III) erhalten.
Achievable rates and outage probability of cognitive radio with dynamic frequency hopping under imperfect spectrum sensing (2015)

In this study, the authors propose simple methods to evaluate the achievable rates and outage probability of a cognitive radio (CR) link that takes into account the imperfectness of spectrum sensing. In the considered system, the CR transmitter and receiver correlatively sense and dynamically exploit the spectrum pool via dynamic frequency hopping. Under imperfect spectrum sensing, false‐alarm and miss‐detection occur which cause impulsive interference emerged from collisions due to the simultaneous spectrum access of primary and cognitive users. That makes it very challenging to evaluate the achievable rates. By first examining the static link where the channel is assumed to be constant over time, they show that the achievable rate using a Gaussian input can be calculated accurately through a simple series representation. In the second part of this study, they extend the calculation of the achievable rate to wireless fading environments. To take into account the effect of fading, they introduce a piece‐wise linear curve fitting‐based method to approximate the instantaneous achievable rate curve as a combination of linear segments. It is then demonstrated that the ergodic achievable rate in fast fading and the outage probability in slow fading can be calculated to achieve any given accuracy level.
A Sulfonoglycolipid with Na+, K+-ATPase Inhibitory Activity, Produced by a Cultured Unique Diatom Symbiot Isolated from a Larger Foraminifera (1996)

A unique diatom (Entomoneis sp.) was isolated from a larger foraminifera (Marginopora vertebralis) and was successfully mass cultured. 6-Sulfo-O-alpha-D-quinovopyranosyldiacylglycerol was isolated from this diatom as an Na+,K+-ATPase inhibitor.
Functional Neoglycopeptides: Synthesis and Characterization of a New Class of MUC1 Glycoprotein Models Having Core 2-Based O-Glycan and Complex-Type N-Glycan Chains (2009)

An efficient protocol for the construction of MUC1-related glycopeptide analogues having complex O-glycan and N-glycan chains was established by integrating chemical and enzymatic approaches on the functional polymer platforms. We demonstrated the feasibility of sortase A-mediated ligation between two glycopeptide segments by tagging with signal peptides, LPKTGLR and GG, at each C- or N-terminal position. Structural analysis of the macromolecular N,O-glycopeptides was performed by means of ESI-TOFMS (MS/MS) equipped with an electron-captured dissociation device. Immunological assay using MUC1 glycopeptides synthesized in this study revealed that N-glycosylation near the antigenic O-glycosylated PDTR motif did not disturb the interaction between the anti-MUC1 monoclonal antibody and this crucial O-glycopeptide moiety. NMR study indicated that the N-terminal immunodominant region [Ala-Pro-Asp-Thr(O-glycan)-Arg] forms an inverse gamma-turn-like structure, while the C-terminal region composed of N-glycopeptide and linker SrtA-peptide was proved to be an independently random structure. These results indicate that the bulky O- and N-glycan chains can function independently as disease-relevant epitopes and ligands for carbohydrate-binding proteins, when both are combined by an artificial intervening peptide having a possible effect of separating N- and C-terminal regions. The present strategy will greatly facilitate rapid synthesis of multiply functionalized complex neoglycopeptides as new types of convenient tools or models for the investigation of thhe structure-function relationship of various glycoproteins and development of novel class glycopeptide-based biopharmaceuticals, drug delivery systems, and biomedical materials.
Detailed comparison between the wall thickness and voltages in chronic myocardial infarction (2018)

Although far-field voltages gradually increase with the WT, near-field does not. The three-dimensional-mapping system preferentially annotates the near-field components in thinner areas (center of the scar) and the far-field component in thicker areas when building a voltage map. Critical sites of VT are distributed in WT: 1 to 4 mm areas.
Trisubstituted (E)-Alkene Dipeptide Isosteres as β-Turn Promoters in the Gramicidin S Cyclodecapeptide Scaffold (2006)

[reaction: see text] A concise synthesis of a gramicidin S analogue with trisubstituted (E)-alkene dipeptide isostere (TEADI) replacements at both d-Phe-Pro positions was realized. Conformational analysis demonstrated that TEADIs can serve as type II beta-turn promoters in a cyclic scaffold and successfully mimic a proline residue.
Linear and Circular Plasmid Content in Borrelia burgdorferi Clinical Isolates (2003)

The genome of Borrelia burgdorferi, the etiologic agent of Lyme disease, is composed of a linear chromosome and more than 20 linear and circular plasmids. Typically, plasmid content analysis has been carried out by pulsed-field gel electrophoresis and confirmed by Southern hybridization. However, multiple plasmids of virtually identical sizes (e.g., lp28 and cp32) complicate the interpretation of such data. The present study was undertaken to investigate the complete plasmid complements of B. burgdorferi clinical isolates cultivated from patients from a single region where early Lyme disease is endemic. A total of 21 isolates obtained from the skin biopsy or blood samples of Lyme disease patients were examined for their complete plasmid complements by Southern hybridization and plasmid-specific PCR analysis. All clinical isolates harbored at least six of the nine previously characterized cp32s. Fourteen isolates harbored all B31-like linear plasmids, and seven isolates simultaneously lacked lp56, lp38, and some segments of lp28-1. The distinctive plasmid profile observed in these seven isolates was specific to organisms that had ribosomal spacer type 2 and pulsed-field gel type A, which implies a clonal origin for this genotype. The presence of nearly identical complements of multiple linear and circular plasmids in all of the human isolates suggests that these plasmids may be particularly necessary for infection, adaptation, and/or maintenance in the infected host.
Data from Focal Adhesion Kinase Promotes the Aggressive Melanoma Phenotype (2023)

&lt;div&gt;Abstract&lt;p&gt;Malignant melanoma continues to remain a significant health threat, with death often occurring as a result of metastasis. The metastatic phenotype typically is characterized by augmented tumor cell invasion and migration in addition to tumor cell plasticity as shown by vasculogenic mimicry. Therefore, understanding the molecular mechanisms that promote an aggressive phenotype is essential to predicting the likelihood of metastasis at a stage when intervention may be possible. This study focuses on the role of focal adhesion kinase (FAK), a cytoplasmic tyrosine kinase important for many cellular processes, including cell survival, invasion, and migration. We found FAK to be phosphorylated on its key tyrosine residues, Tyr&lt;sup&gt;397&lt;/sup&gt; and Tyr&lt;sup&gt;576&lt;/sup&gt;, in only aggressive uveal and cutaneous melanoma cells, which correlates with their increased invasion, migration, and vasculogenic mimicry plasticity. Additionally, we confirmed the presence of FAK phosphorylated on Tyr&lt;sup&gt;397&lt;/sup&gt; and Tyr&lt;sup&gt;576&lt;/sup&gt; in both cutaneous and uveal melanoma tumors &lt;i&gt;in situ&lt;/i&gt;. Examination of a functional role for FAK in aggressive melanoma revealed that disruption of FAK-mediated signal transduction pathways, through the expression of FAK-related nonkinase (FRNK), results in a decrease in melanoma cell invasion, migration, and inhibition of vasculogenic mimicry. Moreover, we found that FRNK expression resulted in a down-regulation of Erk1/2 phosphorylation resulting in a decrease in urokinase activity. Collectively, these data suggest a new mechanism involved in promoting the aggressive melanoma phenotype through FAK-mediated signal transduction pathways, thus providing new insights into possible therapeutic intervention strategies.&lt;/p&gt;&lt;/div&gt;
Nash Bargaining without Scale Invariance (2011)

We present a characterization of the Nash Bargaining Solution on a domain which is not closed under Scale Invariance. The characterization on this restricted domain relies on Symmetry, Efficiency, Translation Invariance, the Independence of Irrelevant Alternatives and Continuity, but does not require Scale Invariance. Surprisingly, without continuity there exist a wide variety of bargaining solutions that satisfy the remaining axioms. Keywords: 1.
An Engineered Metal Sensor Tunes the Kinetics of Synaptic Transmission (2015)

In calcium, synaptotagmin-1 triggers neurotransmitter release by interacting with membranes. Here, we demonstrate that intrinsic properties of this interaction control the time course of synaptic transmission. We engineered a "chimera" using synaptotagmin-1 and elements of a slower isoform, synaptotagmin-7. When expressed in neurons, the chimera slowed the rate of neurotransmitter release. Furthermore, unlike native synaptotagmin-1, the chimera was able to function robustly in the presence of strontium-a metal not present in cells. We exploited this ability to show that a key function of synaptotagmin-1 is to penetrate cell membranes. This work sheds light on fundamental mechanisms of neurotransmitter release.
Synthesis of a Novel Poly(binaphthylene ether) Containing Trifluoromethyl Groups with a Low Dielectric Constant (2006)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTSynthesis of a Novel Poly(binaphthylene ether) Containing Trifluoromethyl Groups with a Low Dielectric ConstantKousuke Tsuchiya, Yuji Shibasaki, Masahiro Aoyagi, and Mitsuru UedaView Author Information Department of Organic and Polymeric Materials, Graduate School of Science and Engineering, Tokyo Institute of Technology, 2-12-1 O-okayama, Meguro-ku, Tokyo 152-8552, Japan, and National Institute of Advanced Industrial Science and Technology(AIST), Tsukuba Central 2, 1-1-1 Umazono, Tukuba, Ibaraki 305-8568, Japan Cite this: Macromolecules 2006, 39, 11, 3964–3966Publication Date (Web):April 27, 2006Publication History Received6 October 2005Revised23 March 2006Published online27 April 2006Published inissue 1 May 2006https://pubs.acs.org/doi/10.1021/ma0521607https://doi.org/10.1021/ma0521607brief-reportACS PublicationsCopyright © 2006 American Chemical SocietyRequest reuse permissionsArticle Views882Altmetric-Citations51LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Chemical structure,Materials,Monomers,Polymerization,Polymers Get e-Alerts
177Lu‐PSMA radioligand therapy effectiveness in metastatic castration‐resistant prostate cancer: An updated systematic review and meta‐analysis (2022)

This is the first meta-analysis to aggregate the recent randomized controlled trials of PRLT which shows CRPC patients had a higher response to therapy after PRLT compared to controls.
Primary demyelinating disease simulating glioma of the corpus callosum (1981)

Computerized tomography (CT) has made it easier to distinguish tumoral from nontumoral diseases of the central nervous system. In the presence of mass effect, however, this distinction may be difficult or impossible to make. Primary demyelinating disease may occasionally present as a focal cerebral mass. The authors report three cases of primary demyelinating disease of the brain involving the corpus callosum and periventricular white matter and associated with mass effect, which proved difficult to differentiate from infiltrating "butterfly" gliomas.
Phytochemical Characterizations of Maranthes polyandra (Benth.) Prance (2022)

Two new ursane-type triterpenoids, named Polyanside A (<b>1</b>) and B (<b>2</b>), along with eleven known compounds (<b>3</b>-<b>13</b>), were isolated and elucidated from <i>Maranthes polyandra</i> (Benth.) Prance. The structures of these compounds were elucidated based on chemical evidence and multiple spectroscopic data. Isolated compounds were evaluated for anti-cancer, anti-inflammatory activities, and cytotoxicity on a normal human cell line (BJ). None of them showed activity and cytotoxicity. The hexane fraction was analyzed by GC-MS, resulting in the identification of forty-one compounds. This is the first comprehensive study on the phytochemistry of <i>M. polyandra</i>.
Cytoskeletal restraints regulate homotypic ALCAM-mediated adhesion through PKCα independently of Rho-like GTPases (2004)

The activated leukocyte cell adhesion molecule (ALCAM) is dynamically regulated by the actin cytoskeleton. In this study we explored the molecular mechanisms and signaling pathways underlying the cytoskeletal restraints of this homotypic adhesion molecule. We observed that ALCAM-mediated adhesion induced by cytoskeleton-disrupting agents is accompanied by activation of the small GTPases RhoA, Rac1 and Cdc42. Interestingly, unlike adhesion mediated by integrins or cadherins, ALCAM-mediated adhesion appears to be independent of Rho-like GTPase activity. By contrast, we demonstrated that protein kinase C (PKC) plays a major role in ALCAM-mediated adhesion. PKC inhibition by chelerythrine chloride and myristoylated PKC pseudosubstrate, as well as PKC downregulation by PMA strongly reduce cytoskeleton-dependent ALCAM-mediated adhesion. Since serine and threonine residues are dispensable for ALCAM-mediated adhesion and ALCAM is not phosphorylated, we can rule out that ALCAM itself is a direct PKC substrate. We conclude that PKCalpha plays a dominant role in cytoskeleton-dependent avidity modulation of ALCAM.
ChemInform Abstract: Isomerization of meta‐Xylene Over Offretite Catalysts (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Mini-incubator For Prolonged Cell Culture And Hypoxia Studies Outside An Incubator (2016)

Frontiers Events is a rapidly growing calendar management system dedicated to the scheduling of academic events. This includes announcements and invitations, participant listings and search functionality, abstract handling and publication, related events and post-event exchanges. Whether an organizer or participant, make your event a Frontiers Event!
Multi-metal coordination polymers grown through hybrid molecular layer deposition (2021)

Coordination polymers deposited by hybrid molecular layer deposition (MLD) techniques are of interest as highly conformal, functional materials. Incorporation of a second metal into these coordination polymers can result in additional functionality or fine tuning of the materials properties. Here, we investigate the deposition of multi-metal coordination polymers using hybrid MLD of Zn-Al and Zn-Hf with ethylene glycol as the organic linker. It is found that facile transmetalation occurs for the Zn-Al films, which results in Al-rich films, but does not take place for the Zn-Hf films. Additionally, the Zn-Hf films are found to be more resilient to ambient conditions than the pure Zn-based coordination polymer.
Synergistic induction of interleukin‐6 by tumor necrosis factor and lithium chloride in mice: Possible role in the triggering and exacerbation of psoriasis by lithium treatment (1992)

One of the side effects of treatment of manic depressive disease with lithium salts is the triggering or aggravation of psoriasis. In a murine model, subcutaneous (s.c.) injection of a combination of tumor necrosis factor (TNF) and lithium chloride (LiCl) induces a psoriasiform inflammatory reaction. Recent studies suggest that interleukin (IL)-6 and its inducer TNF may play an important role in the pathophysiology of psoriasis. To understand the mechanism involved in the exacerbation of psoriasis by lithium salts, the IL-1, IL-6 and granulocyte-macrophage colony-stimulating factor (GM-CSF) levels in murine skin injected with TNF in combination with LiCl were studied. IL-6 levels in skin extracts of mice treated s.c. with a combination of TNF and LiCl were considerably increased as compared to the levels found in skin extracts from mice treated with TNF or LiCl alone. In contrast, in the same skin extracts IL-1 levels were not changed and GM-CSF was even not detectable. Although less pronounced, increased IL-6 levels could also be found in the sera of mice treated s.c. with TNF and LiCl. Injection with IL-1, interferon-gamma, lipopolysaccharide, or phorbol 12-myristate 13-acetate also induced IL-6 in murine skin. However, these IL-6 levels were not enhanced by co-treatment with LiCl. Likewise, on inflammatory reaction could be seen in mice treated with these agents. These results suggest a role for endogenous TNF and IL-6 in the triggering or aggravation of psoriasis in lithium-treated patients.