gebhart/patrepeval huggingface dataset:
Intracrystalline diffusion in Metal Organic Framework during heterogeneous catalysis: Influence of particle size on the activity of MIL-100 (Fe) for oxidation reactions (2011)

Three MIL-100 (Fe) samples differing in average crystal size (from 60-70 to >400 nm) have been synthesized by microwave heating using three HF/Fe(3+) ratios. Oxidation of diphenylmethane with tert-butylhydroperoxide (TBHP) and thiophenol with oxygen are catalyzed by three MIL-100 (Fe) samples with similar reaction rates regardless of its average particle size. In contrast, the activity of the three MIL-100 (Fe) samples for the oxidation of bulky triphenylmethane by TBHP largely depends on the average crystal size of the sample: the smaller the average particle size, the larger the initial reaction rate of triphenylmethane oxidation. These results show that diffusion limitation takes place on MOF catalysis depending on the substrate size and provides indirect evidence that these reactions take place inside the intracrystalline space of the porous catalysts.
NADH inhibition of SIRT1 links energy state to transcription during time-restricted feeding (2021)

In mammals, circadian rhythms are entrained to the light cycle and drive daily oscillations in levels of NAD<sup>+</sup>, a cosubstrate of the class III histone deacetylase sirtuin 1 (SIRT1) that associates with clock transcription factors. Although NAD<sup>+</sup> also participates in redox reactions, the extent to which NAD(H) couples nutrient state with circadian transcriptional cycles remains unknown. Here we show that nocturnal animals subjected to time-restricted feeding of a calorie-restricted diet (TRF-CR) only during night-time display reduced body temperature and elevated hepatic NADH during daytime. Genetic uncoupling of nutrient state from NADH redox state through transduction of the water-forming NADH oxidase from Lactobacillus brevis (LbNOX) increases daytime body temperature and blood and liver acyl-carnitines. LbNOX expression in TRF-CR mice induces oxidative gene networks controlled by brain and muscle Arnt-like protein 1 (BMAL1) and peroxisome proliferator-activated receptor alpha (PPARα) and suppresses amino acid catabolic pathways. Enzymatic analyses reveal that NADH inhibits SIRT1 in vitro, corresponding with reduced deacetylation of SIRT1 substrates during TRF-CR in vivo. Remarkably, Sirt1 liver nullizygous animals subjected to TRF-CR display persistent hypothermia even when NADH is oxidized by LbNOX. Our findings reveal that the hepatic NADH cycle links nutrient state to whole-body energetics through the rhythmic regulation of SIRT1.
Spinopelvic Parameters in Asymptomatic Subjects Without Spine Disease and Deformity (2017)

The pooled results and developed methodology can be used as diagnostic criteria for evaluation of the spinopelvic parameters, planning of surgical interventions and evaluation of the treatment effect.
Ifosfamide in the Treatment of Relapsed Lymphoma (1998)

Research Articles| June 10 1998 Ifosfamide in the Treatment of Relapsed Lymphoma Subject Area: Oncology M. Reiser; M. Reiser Search for other works by this author on: This Site PubMed Google Scholar P. Borchmann; P. Borchmann Search for other works by this author on: This Site PubMed Google Scholar V. Diehl; V. Diehl Search for other works by this author on: This Site PubMed Google Scholar A. Engert A. Engert Search for other works by this author on: This Site PubMed Google Scholar Onkologie (1998) 21 (Suppl. 2): 26–29. https://doi.org/10.1159/000054967 Article history Published Online: June 10 1998 Content Tools Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn Email Tools Icon Tools Get Permissions Cite Icon Cite Search Site Citation M. Reiser, P. Borchmann, V. Diehl, A. Engert; Ifosfamide in the Treatment of Relapsed Lymphoma. Onkologie 1 June 1998; 21 (Suppl. 2): 26–29. https://doi.org/10.1159/000054967 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsOnkologie Search Advanced Search This content is only available via PDF. 1998Copyright / Drug Dosage / DisclaimerCopyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Article PDF first page preview Close Modal You do not currently have access to this content.
Supplementary fig 3 from High-dose per Fraction Radiotherapy Induces Both Antitumor Immunity and Immunosuppressive Responses in Prostate Tumors (2023)

&lt;p&gt;Supplemental 3. Radiation temporarily increases tumor resident MDSC population in MycCap tumors&lt;/p&gt;
Frequency-Domain 2×2 Mimo Equalizer With Stokes Space Updating Algorithm (2016)

We propose a novel frequency-domain Stokes space algorithm. Its low implementation complexity architecture allows merging static and dynamic 2×2 MIMO equalization in a single stage
Pointable (2011)

Selecting and moving digital content on interactive tabletops often involves accessing the workspace beyond arm's reach. We present Pointable, an in-air, bimanual perspective-based interaction technique that augments touch input on a tabletop for distant content. With Pointable, the dominant hand selects remote targets, while the non-dominant hand can scale and rotate targets with a dynamic C/D gain. We conducted 3 experiments; the first showed that pointing at a distance using Pointable has a Fitts' law throughput comparable to that of a mouse. In the second experiment, we found that Pointable had the same performance as multi-touch input in a resize, rotate and drag task. In a third study, we observed that when given the choice, over 75% of participants preferred to use Pointable over multi-touch for target manipulation. In general, Pointable allows users to manipulate out-of-reach targets, without loss of performance, while minimizing the need to lean, stand up, or involve collocated collaborators.
Antitubercular Agents. Part 1. Synthesis of Phthalimido‐ and Naphthalimido‐Linked Phenazines as New Prototype Antitubercular Agents. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Biology-guided adaptive radiotherapy (BiGART) – more than a vision? (2013)

Acta Oncologica can this year celebrate its 50 years jubilee as the leading Scandinavian journal in oncology. As a part of this celebration the 11th Acta Oncologica Symposium was held in Aarhus, Denmark, on June 11 – 13, 2013. The symposium was dedicated to aspects of Biology-Guided Adaptive Radiotherapy (BiGART). The 172 participants of the meeting included physicians, physicists, radiobiologists and other scientists with an active interest in this specifi c area. The format included invited presentations, proffered papers and discussion rounds. More than 100 abstracts were submitted to the conference. Acta Oncologica has sponsored scientifi c symposia since 1989. The aim of this activity has been to focus on oncological issues of emerging interest, preferably with a multi-disciplinary or multi-professional approach. The current series of Acta Oncologica meetings with focus on radiotherapy (RT) have encompassed stereotactic body RT (SBRT) [1], image-guided RT (IGRT) [2,3], adaptive RT (BiGART) [4] and particle RT [5]. Other topics have over the years included sentinel lymph node biopsy in breast cancer, prostate cancer, normal tissue morbidity, breast cancer, and rehabilitation. The goal of BiGART is adaptation of RT in time and space based on biological and anatomical features, maximizing the therapeutic ratio for each individual patient. Key topics for the BiGART2013 conference included:
Photochemistry of cyclopentanone derivatives in the synthesis of prostaglandin and thromboxane analogues (1989)

M. Azadi-Ardakani, G. C. Loftus, A. M. M. Mjalli, R. F. Newton and S. M. Roberts, J. Chem. Soc., Chem. Commun., 1989, 1709 DOI: 10.1039/C39890001709
Prevalence of age-related macular degeneration associated genetic risk factors and 4-year progression data in the Irish population (2018)

The prevalence of risk-associated genes and 4-year progression rates of AMD in this Ireland cohort are comparable with other Caucasian populations. CFH Y402H is associated with disease progression, with soft drusen and hyperpigmentation as high-risk features.
New Tools for Fracture Design Optimization (2004)

Designing an effective and optimum fracture treatment is a complex and time-consuming task, especially in the case of new fields where the number of unknown variables is much larger than the number of known variables. Even with growing field maturity, changes in the fracture design often tend to be marginal and do not lead to a drastic improvement in the fracture design manifested by the post fracture production. This is not say that even marginal treatments are economically unattractive. Fracturing even when done badly is still one of the most economically rewarding petroleum operations. What we are addressing is a much more advanced and refined approach to design where economic benefits can be doubled or tripled.One explanation for the absence of continuous improvement of fracture treatments is lack of the appropriate tools to perform a thorough data-mining task, which would lead to a definitive improvement in post fracture production benefits.The appropriate tools for this task are presented in this paper. Although these tools are commonly used in other industries, they are still relatively new to most petroleum engineers.This paper provides an introduction to the technology and procedures to mine large databases for hidden, but valuable underlying relationships.An included comprehensive case study presents the workflow of the data mining approach to fracture optimization.A combination of Neural Networks and Genetic Algorithms, both regarded as artificial intelligence tools, are first applied to the data.The Neural Network is trained on historic data and captures the relationship between a certain data set of input parameters and the corresponding output parameter. This relationship is stored in the architecture of the Neural Network.In a following step, the Neural Network is used by the Genetic Algorithm optimization tool to calculate the optimum values for the various input parameters: in this case to maximize the output – the production after fracture treatment. Genetic algorithms are inspired by Darwin's law for the survival of the fittest. For the particular case the fittest values for the different parameter are those, which generate a high post fracture production.The results are than verified with the Unified Fracture Design approach. Neural Networks use historic data to train. It is required that the data show significant variation to capture the relationships between input and output. Data sets, which show too low variation in production (mainly on the poor side), cannot be optimized based on the artificial intelligence approach. For this case data mining results are integrated into the Unified Fracture Design approach, which will point to the optimum design.The combination of data mining with an appropriate fracture optimization design approach is a powerful combination in production engineering and one assured to provide large incremental economic benefits to the industry.
Digital geometry processing with discrete exterior calculus (2013)

An introduction to geometry processing using discrete exterior calculus (DEC), which provides a simple, flexible, and efficient framework for building a unified geometry-processing platform. The course provides essential mathematical background as well as a large array of real-world examples. It also provides a short survey of the most relevant recent developments in digital geometry processing and discrete differential geometry. Compared to previous SIGGRAPH courses, this course focuses heavily on practical aspects of DEC, with an emphasis on implementation and applications.
Overview of Silica-Polymer Nanostructures for Waterborne High-Performance Coatings (2021)

Combining organic and inorganic components at a nanoscale is an effective way to obtain high performance coating materials with excellent chemical and physical properties. This review focuses on recent approaches to prepare hybrid nanostructured waterborne coating materials combining the mechanical properties and versatility of silica as the inorganic filler, with the flexural properties and ease of processing of the polymer matrix. We cover silica-polymer coupling agents used to link the organic and inorganic components, the formation of hybrid films from these silica-polymer nanostructures, and their different applications. These hybrid nanostructures can be used to prepare high performance functional coatings with different properties from optical transparency, to resistance to temperature, hydrophobicity, anti-corrosion, resistance to scratch, and antimicrobial activity.
The HLA Ligand Atlas - A resource of natural HLA ligands presented on benign tissues (2019)

ABSTRACT The human leukocyte antigen (HLA) complex controls adaptive immunity by presenting defined fractions of the intracellular and extracellular protein content to immune cells. Here, we describe the HLA Ligand Atlas, an extensive collection of mostly matched HLA-I and -II ligandomes from 225 benign samples (29 tissues, 21 subjects). The initial release covers 51 HLA-I and 86 HLA-II allotypes presenting 89,853 HLA-I- and 140,861 HLA-II ligands. We observe that the immunopeptidomes differ considerably between tissues and individuals on both source protein and HLA-ligand level. 1,407 HLA-I ligands stem from non-canonical genomic regions. We highlight the importance of comparatively analyzing both benign and malignant tissues to inform tumor association, based on a case study in three glioblastoma patients. The resource provides insights into applied and basic immune-associated questions in the context of cancer immunotherapy, infection, transplantation, allergy, and autoimmunity. It is publicly available at www.hla-ligand-atlas.org .
Analysis of micro-Raman spectra combined with electromagnetic simulation and stress simulation for local stress distribution in Si devices (2012)

We have developed a Raman simulation method using a finite-difference time-domain electromagnetic simulation and a finite element method stress simulation for precise local stress analysis of Si devices. This method accounts for the modification of light distribution by the sample structure, which significantly affects the Raman spectra near a metal gate structure with high refractive index and extinction coefficient. The precise stress estimation by this method is verified by analyzing polarized UV Raman measurements of a metal-oxide semiconductor field-effect transistor structure with a metal gate.
Steward: Scaling Byzantine Fault-Tolerant Systems to Wide Area Networks (2005)

Abstract — This paper presents the first hierarchical Byzantine fault-tolerant replication architecture suitable to systems that span multiple wide area sites. The architecture confines the effects of any malicious replica to its local site, reduces message complexity of wide area communication, and allows read-only queries to be performed locally within a site for the price of additional standard hardware. We present proofs that our algorithm provides safety and liveness properties. A prototype implementation is evaluated over several network topologies and is compared with a flat Byzantine fault-tolerant approach. The experimental results show considerable improvement over flat Byzantine replication algorithms, bringing the performance of Byzantine replication closer to existing benign fault-tolerant replication techniques over wide area networks. Index Terms — Fault-tolerance, scalability, wide-area networks I.
Design of 8T-nanowire RAM array (2013)

SRAM based memory blocks constitute a major part of state-of-art processor architectures. Increasing complexity and variation in nanometer CMOS fabrication has prompted exploration of memory circuits based on emerging nanofabrics. In this work, we propose a new 8T-Nanowire based RAM (8T-NWRAM) circuit for high density memory arrays. The design is based on N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> ASIC, a nanofabric using combination of crosspoint nanowire FETs and integration with metal interconnects. The layout implementation is optimized to reduce bitline load and achieve high performance. The upper bound on bitcell area is 0.1μm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , which is 50% more compared to conventional 6T-SRAM. However, both performance and leakage are significantly improved. Circuit simulation using N <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> ASIC 2C-xnwFET device models show improvements of >2X in read time and ~4X in write time compared to high performance SRAM. The average leakage power at 0.2nW is ~20X smaller compared to high performance SRAM. In comparison with existing 10T-NWRAM, the 8T-NWRAM provides a twofold improvement in read time and ~46% faster write time, but at the expense of ~30% increase in area and average leakage power. Thus, 8T-NWRAM is a viable alternative to 10T-NWRAM for performance vs area/leakage design requirement. We also study the impact of supply noise induced clock jitter on NWRAM circuits and propose adequate design margin to ensure bitcell stability.
ChemInform Abstract: Back‐Reactions in the Photochemical Disproportionation of Cp2Mo2(CO)6 (Cp: C5H4CH3) and the Wavelength‐Dependent Photochemistry of the Cp2Mo2(CO)6 Complex with PPh3. (1987)

Abstract Irradiation of (I) with PPh 3 in CH 2 Cl 2 proceeds to give (II) and (III), while a similar disproportionation reaction in benzene or other nonpolar solvents does not occur at the same wavelength but for λ = 290 nm, because a secondary photochemical reaction of the initially formed (II) takes place to give (IV).
An efficient synaptic architecture for artificial neural networks (2017)

Artificial neural networks (ANN) have revolutionized the field of machine learning by providing impressive human-like performance in solving real-world tasks in computer vision, speech recognition, or complex strategic games. There is a significant interest in developing non-von Neumann coprocessors for the training of ANNs, where resistive memory devices serve as synaptic elements. However, interdevice variability, limited dynamic range and resolution, nonlinearity and asymmetric switching characteristics pose important technical challenges. We investigate the use of multi-memristive synapses to overcome these challenges. We present a detailed experimental characterization of conductance changes using a phase-change memory chip fabricated in the 90nm technology node and show how multi-memrisive synapses can address the limitations of memristive devices for synaptic implementations. Simulations show that an ANN trained with backpropagation can achieve competitive classification accuracies using such a scheme.
Influence of Donor Histology on Outcome in Patients Undergoing Transplantation for Hepatitis C (2007)

A number of risk factors for detrimental outcome in HCV-positive patients after liver transplantation have been identified. In particular, older donor age significantly impaired outcome in recent analysis, but due to donor shortage it is not possible to provide young grafts for all HCV-positive patients. Our data show that donor histology is helpful in identifying patients with more severe recurrent hepatitis prior to transplantation, and that especially in older donors, prolonged intensive care hospitalization should be avoided.
Fiber Bragg gratings based multiwavelength cross-connect with high dynamic range (2003)

A reconfigurable multiwavelength crossconnect (MXC) based in fiber Bragg gratings integrated with optical limiting amplifiers is investigated. The MXC has high input dynamic range of over 20 dB. Small power penalty of 0.6 and 1.0 dB for the crossconnect and passing through signal is demonstrated for a 2.5 Gbit/s/spl times/2 100-km system.
An Efficient Caching Scheme for Personal Communication Service Networks (2004)

Personal communication service (PCS) networks support the delivery of communication services as the mobile user moves from one region to another. When a mobile user receives a call, the network has to quickly determine its current location. The existing approach suffers from high delay in locating the mobile since the mobile's current location has to be always consulted on the location databases. Caching the location of the remote mobile is useful to reduce this delay. However, the longer the useless record caused by the movement of the mobile remains in a cache, the higher the degradation of cache memory utilization is imposed on a system. In this paper, we propose an efficient caching scheme that a cached record is not allowed to remain over the predefined time, called a time-threshold, in a cache. A long time-threshold may cause to increase the obsoleteness of the cached record. In contrast, a short time-threshold may cause to degrade memory utilization. This paper finds the optimal time-threshold to enlarge cache memory utilization. Also, we provide a unique solution for determining the optimal time-threshold, and study the effects of changing the important parameters of mobility, calling patterns, and network conditions on the optimal time-threshold. Furthermore, we compare the performance of the proposed caching call delivery scheme and the existing call delivery schemes.