gebhart/patrepeval huggingface dataset:
Digital signal processing system design: using labview and TMS320C6000 (2005)

LabVIEW, developed by National Instruments, is a graphical programming environment suited for high-level or system-level design. It allows the integration of different signal processing components or subsystems within a graphical framework. This paper introduces a LabVIEW-based book being written for the purpose of furnishing a textbook for DSP laboratory courses offered at many engineering schools. Two examples, namely signal filtering and DTMF receiver, are presented to show how DSP systems are designed using the LabVIEW graphical programming environment. In addition, the book presents the way to implement any desired component(s) of a DSP system on Texas Instruments C6x DSK boards. It is shown how the real-time data exchange feature of the TI Code Composer Studio allows users to establish a communication link between a host PC running LabVIEW and a C6x DSK board.
Susceptibility effects in porous media in the presence of flow (1993)

Magnetic resonance (MR) imaging of microvascular flow is an important topic in biomedicine because it permits access to the functional state of a biologic system. The internal heterogeneous magnetic field due to susceptibility differences within tissues is one of the factors that can affect signal intensity. A glass bead phantom simulating a porous medium was used to experimentally study the effect of the internal magnetic field on MR flow measurements. A physical model was developed to simulate the paths of the moving spins and the local magnetic field distribution in the medium to estimate the signal intensity with spin-phase analysis. The susceptibility variation inside the glass bead phantom was estimated by comparing the simulation results with the experimental data. Experiments were also performed with a tissue-simulating phantom, and the results indicated that the effect of the internal field inhomogeneity on in vivo microvascular flow measurements was negligible.
Wide-Bite-Angle Diphosphine Ligands in Thermally Activated Delayed Fluorescent Copper(I) Complexes: Impact on the Performance of Electroluminescence Applications (2021)

We report a series of seven cationic heteroleptic copper(I) complexes of the form [Cu(P^P)(dmphen)]BF<sub>4</sub>, where dmphen is 2,9-dimethyl-1,10-phenanthroline and P^P is a diphosphine chelate, in which the effect of the bite angle of the diphosphine ligand on the photophysical properties of the complexes was studied. Several of the complexes exhibit moderately high photoluminescence quantum yields in the solid state, with Φ<sub>PL</sub> of up to 35%, and in solution, with Φ<sub>PL</sub> of up to 98%. We were able to correlate the powder photoluminescence quantum yields with the % V<sub>bur</sub> of the P^P ligand. The most emissive complexes were used to fabricate both organic light-emitting diodes and light-emitting electrochemical cells (LECs), both of which showed moderate performance. Compared to the benchmark copper(I)-based LECs, [Cu(dnbp)(DPEPhos)]<sup>+</sup> (maximum external quantum efficiency, EQE<sub>max</sub> = 16%), complex <b>3</b> (EQE<sub>max</sub> = 1.85%) showed a much longer device lifetime (<i>t</i><sub>1/2</sub> = 1.25 h and >16.5 h for [Cu(dnbp)(DPEPhos)]<sup>+</sup> and complex <b>3</b>, respectively). The electrochemiluminescence (ECL) properties of several complexes were also studied, which, to the best of our knowledge, constitutes the first ECL study for heteroleptic copper(I) complexes. Notably, complexes exhibiting more reversible electrochemistry were associated with higher annihilation ECL as well as better performance in a LEC.
Reactions of Phosphorus Trioxide with Some Compounds of the Group III Elements (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of Phosphorus Trioxide with Some Compounds of the Group III ElementsJean G. Riess and John R. Van WazerCite this: J. Am. Chem. Soc. 1966, 88, 10, 2339–2340Publication Date (Print):May 1, 1966Publication History Published online1 May 2002Published inissue 1 May 1966https://pubs.acs.org/doi/10.1021/ja00962a059https://doi.org/10.1021/ja00962a059research-articleACS PublicationsRequest reuse permissionsArticle Views84Altmetric-Citations17LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Amines immobilized on a solid support for postcombustion CO2 capture–A preliminary analysis of the performance in a VSA or TSA process based on the adsorption isotherms and kinetic data (2009)

A series of different amines was immobilized on a silica support by grafting or impregnation and tested for CO2 adsorption in simulated flue gases. This paper compares the adsorption isotherms and the cyclic adsorption capacities of these materials. Furthermore, we estimate the diffusion rate of CO2 from simulations of the breakthrough curves and discuss some aspects of the design of a potential adsorption process for CO2 capture.
Fluoride-promoted, dye-sensitized photooxidation of enols (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFluoride-promoted, dye-sensitized photooxidation of enolsHarry H. Wasserman and James E. PickettCite this: J. Am. Chem. Soc. 1982, 104, 17, 4695–4696Publication Date (Print):August 1, 1982Publication History Published online1 May 2002Published inissue 1 August 1982https://pubs.acs.org/doi/10.1021/ja00381a040https://doi.org/10.1021/ja00381a040research-articleACS PublicationsRequest reuse permissionsArticle Views424Altmetric-Citations57LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The Quality of Multimedia: Challenges and Trends [From the Guest Editors] (2011)

One of the most visible consequences of progress in multimedia has been an increase in quality of the products and services offered. Nowadays, there is no longer only a question of which features are to be included in multimedia applications but also how well they contribute to the quality of user experience.
Hydrolyzable Tannins, the Active Constituents of Three Greek Cytinus Taxa against Several Tumor Cell Lines. (2001)

Hydrolyzable tannins were found to be the active cytotoxic constituents of three Greek Cytinus taxa: Cytinus ruber, Cytinus hypocistis subsp. hypocistis and Cytinus hypocistis subsp. orientalis. The cytotoxic activity was evaluated against a broad spectrum of cancer cell lines. The structure of the active compounds was investigated with NMR and electrospray-MS/MS techniques.
PATHWAY LOGIC MODELING OF PROTEIN FUNCTIONAL DOMAINS IN SIGNAL TRANSDUCTION (2003)

Protein functional domains (PFDs) are consensus sequences within signaling molecules that recognize and assemble other signaling components into complexes. Here we describe the application of an approach called Pathway Logic to the symbolic modeling signal transduction networks at the level of PFDs. These models are developed using Maude, a symbolic language founded on rewriting logic. Models can be queried (analyzed) using the execution, search and model-checking tools of Maude. We show how signal transduction processes can be modeled using Maude at very different levels of abstraction involving either an overall state of a protein or its PFDs and their interactions. The key insight for the latter is our algebraic representation of binding interactions as a graph.
Effect of Using a Combination of Lid Wipes, Eye Drops, and Omega-3 Supplements on Meibomian Gland Functionality in Patients With Lipid Deficient/Evaporative Dry Eye (2015)

The combination treatment regimen resulted in significant improvement in meibomian gland functionality and dry eye symptoms. No safety issues were observed.
Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease (2022)

Biobanks facilitate genome-wide association studies (GWASs), which have mapped genomic loci across a range of human diseases and traits. However, most biobanks are primarily composed of individuals of European ancestry. We introduce the Global Biobank Meta-analysis Initiative (GBMI)-a collaborative network of 23 biobanks from 4 continents representing more than 2.2 million consented individuals with genetic data linked to electronic health records. GBMI meta-analyzes summary statistics from GWASs generated using harmonized genotypes and phenotypes from member biobanks for 14 exemplar diseases and endpoints. This strategy validates that GWASs conducted in diverse biobanks can be integrated despite heterogeneity in case definitions, recruitment strategies, and baseline characteristics. This collaborative effort improves GWAS power for diseases, benefits understudied diseases, and improves risk prediction while also enabling the nomination of disease genes and drug candidates by incorporating gene and protein expression data and providing insight into the underlying biology of human diseases and traits.
Glycoprotein synthesis (2023)

Methods for making glycoproteins, both in vitro and in vivo, are provided. One method involves incorporating an unnatural amino acid into a protein and attaching one or more saccharide moieties to the unnatural amino acid. Another method involves incorporating an unnatural amino acid that includes a saccharide moiety into a protein. Proteins made by both methods can be further modified with additional sugars.
Effect of potassium on the hydrogenation of CO and CO/sub 2/ over supported Rh catalysts. Technical report (1986)

The reactions of hydrogen with carbon monoxide and carbon dioxide over Rh/Al2O3 and Rh/TiO2 films, some of which contained potassium as an additive, have been investigated. For the CO hydrogenation reaction the presence of potassium caused the dissociation or desorption of the gem dicarbonyl, linear CO, and carbonyl hydride species, while it led to an enhancement of the bridged carbonyl species. For Rh/TiO2 films the hydrogenation of CO produced acetone and acetaldehyde as oxygenated products; the bridged carbonyl species was the likely precursor of these products. For the CO2 hydrogenation reaction the presence of potassium caused the dissociation or desorption of all CO species, and oxygenated products were not produced. Potassium significantly poisoned both reactions toward the production of methane.
ASIC Implementation of Highly Reliable IR-UWB Transceiver for Industrial Automation (2016)

Abstract An in-depth treatment of impulse an radio ultra-wideband (IR-UWB) wireless system is provided reviewing theoretical background, proceeding with detailed implementation procedure, and finally giving simulation and test results. This is the first research and prototyping work to be published in the field of IR-UWB that operates in the 6–8 GHz band. The aim of this work is to implement an IR-UWB wireless system for industrial automation that is robust and reliable. To achieve this, an analogue bandwidth of 250 MHz and digital baseband processing at the clock frequency 499.2 MHz were realized in a 250 nm
Inverse Determination of Moving Heat Flux Distributions Using Reduced Order Models (2014)

Optimization-based solutions to inverse problems involve the coupling of an analysis model, such as a finite element model, with a numerical optimization method. The goal is to determine a set of parameters that minimize an objective function that is determined by solving the analysis model. In this paper, we present an approach that dramatically reduces the computational cost for solving this inverse problems in this way by replacing the original full order finite element model (FOM) with a reduced order model (ROM) that is both accurate and quick to compute. The reduced order model is constructed with basis functions generated using proper orthogonal decomposition of set of solutions from the FOM. A discrete Galerkin method is used to project the differential equation on the basis functions. This approach allows us to transform the linear full order finite element model into an equivalent discrete ROM with far fewer unknowns. The method is applied to a parameter estimation problem in heat transfer. Specifically, we determine the parameters governing the magnitude and distribution of an unknown surface heat flux moving at a constant velocity across the surface of a solid bar of material. A finite element model was implemented in the commercial package COMSOL and a corresponding ROM was constructed. The ROM was coupled with an optimization algorithm to determine the parameter values that minimized the distance between the computed surface temperatures and the target surface temperature. The target surface temperature was generated using simulated measurements produced from the full order finite element model. Several optimization methods were used. The results show the approach can recover the parameters with high accuracy with twenty seven FOM runs.
Virologic, immunologic, and clinical follow-up of a couple infected by the human immunodeficiency virus type one, group O (1997)

The pathogenic course (virologic, immunologic, and clinical changes) of infection due to human immunodeficiency virus type one (HIV-1) group O viruses is unknown at present. To address this issue, serial HIV-1 isolates from a married couple (patients A and B) infected with a group O virus were analyzed to determine the temporal association between disease status and alterations in several parameters including plasma viral burden as measured by semiquantitative polymerase chain reaction, changes in CD4+ T cells, presence of neutralizing antibodies, and the ability to induce syncytia on the MT2 cells. For patient A who has been asymptomatic for at least 8 years, both the absence of syncytium-inducing (SI) variants and the presence of autologous and heterologous neutralizing antibodies correlated with a clinically healthier status. In contrast, a switch from NSI to SI variants was observed in patient B in 1990, followed by an expanded in vitro host range, increased viral burden, and a sharp decrease in CD4+ T cells 4 years later. Moreover, plasma obtained from this patient uniformly failed to neutralize both autologous and heterologous viruses. These observations in patient B correlated with a slightly unfavorable clinical status. Based on our preliminary results, it appears that the pathogenic course of infections due to group O viruses is similar to that reported previously for infections due to group M viruses.
Abstract 20129: T Wave Area is an Electrocardiographic Marker of Cardiac Events Following Left Cardiac Sympathetic Denervation (2016)

Introduction: Long QT syndrome (LQTS) is a genetic channelopathy associated with a risk of sudden cardiac death (SCD). Left cardiac sympathetic denervation (LCSD) is one of the current treatment op...
UPLC-MS/MS Determination of Aceclofenac and Diclofenac in Bulk, Dosage forms and in At-line Monitoring of Aceclofenac Synthesis (2014)

Aim:&nbsp;The derivatization product of diclofenac (DCL), aceclofenac (ACL), is a non-steroidal anti-inflammatory drug (NSAID) which causes faster and extended action with reduced gastrointestinal (GI) inflammation. The detection of DCL in ACL bulk and pharmaceutical products indicates incomplete synthesis and hydrolysis.In this article we have developed a UPLC-MS/MS method for analysis of ACL and DCL. The method was designed as an at-line monitoring tool for process analytical technology (PAT) application to ACL synthesis. The method was also applied for analysis of ACL and DCL in bulk and tablets.Methodology:&nbsp;Isocratic elution was performed on a UPLC C18 column (2.1 x 50 mm, 1.7 µm) using a mobile phase consisting of acetonitrile, water and formic acid (80:20:0.5,&nbsp;v/v/v). Flow rate was 0.2 mL/min and total run time was 1 min. Auto-sampler temperature was maintained at 5ºC to prevent any further degradation of ACL. Electrospray positive ionization (ESI +Ve) in multiple-reaction monitoring mode (MRM) was used for the simultaneous determination of ACL and DCL. Monitoring was performed at [M+H]+ 354.23: 250.09 and 296.13:250.1&nbsp;m/z; respectively. The method was validated according to ICH guidelines Q2(R1).Results:&nbsp;The linearity range was 20 – 3000 ng/mL for both drugs. The developed method was accurate and precise (RSD&lt;2%) for the determination of ACL and DCL in single solution (99.65±1.33 and 100.37±1.02 for ACL and DCL; respectively) and laboratory prepared mixtures (101.01±1.07 and 100.45±1.54 for ACL and DCL; respectively). The method was applied to Bristaflam®&nbsp;and Cataflam®&nbsp;tablets and the recovery was 100.95±0.18 and 99.15±0.62; respectively. The average recovery from reaction mixture was101.21±0.06 and 98.89±0.64 for ACL and DCL; respectively.Conclusion:&nbsp;The proposed UPLC-MS/MS method is valid for at-line monitoring of ACL and DCL during PAT application to ACL synthesis and drug determination in bulk and tablets.
Multiphysics System Co-Design of a High-Precision, High-Voltage (±600V) Isolated Hall-Effect Current Sensor (2021)

Hall-Effect current sensor is a transducer type, which senses the strength of a magnetic field caused by the detected current and changes its voltage output accordingly. Linear Hall-Effect integrated circuits (ICs) provide non-invasive, safe sensing, and detection of high DC, AC, and pulse current levels without dissipating additional power associated with resistive current-sensing methods. Typical applications of current sensing include overcurrent protection, monitoring and diagnostics, and closed-loop control in high-voltage, high-current systems. The current sensor options available for high-voltage applications are typically isolated shunt-based, closed-loop Hall-effect, or an in-package based Hall-Effect. The in-package Hall-Effect current sensor technology is preferred as market needs drive highly-integrated, high-performance, and cost-effective solutions. While beneficial, integration leads to multiple design complexities due to increasing system multiphysics interactions. This paper presents a multiphysics system (silicon + package + PCB) co-design of an in-package Hall-Effect current sensor IC that can be adopted early in the design process. The development and implementation of the coupled electrothermal and system modeling methodology are fully detailed. Silicon validation measurements on a high-precision, high-voltage (±600V) Hall-Effect current sensor device are presented that validate the integrity of the multiphysics system co-design modeling and analysis methodology.
Highly Cumulated Radical Cascade Reaction of aza‐1,6‐Enyenes: Stereoselective Synthesis of exo‐Methylene Piperidines (2020)

Treatment of 1,6‐azaeneyne compounds with Ph 3 SnH resulted in the stereoselective formation of 5‐( E )‐alkylidene‐2,3‐ cis ‐piperidine in moderate to good yields. Intermediate products including methylenepyrrolidine and stannomethylene pyrrolidine were also detected in the reaction mixture, suggesting that the reaction progressed via a highly cumulated radical cascade process involving sequential six radical processes, i.e. radical addition, 5‐ exo cyclization, substitution (1,4‐tin migration), 3‐ exo cyclization, ring cleavage of cycloprolane, and hydrogen abstraction from Ph 3 SnH. The product distribution depended on the lower Ph 3 SnH concentration, resulting in higher piperidine yields. The E/Z selectivity of the exo ‐methylene unit was also sensitive to the reaction temperature. The vinylic triphenyltin group was converted into hydrogen and iodine. A kinetic analysis of the reaction indicated that the 1,4‐tin migration and ring expansion progressed as irreversible reactions and that their reaction rates were large enough to progress the cascade reaction smoothly and to prevent side reactions such as hydrogen abstraction from Ph 3 SnH.
CD40 Is Essential in the Upregulation of TRAF Proteins and NF-KappaB-Dependent Proinflammatory Gene Expression after Arterial Injury (2011)

Despite extensive investigations, restenosis, which is characterized primarily by neointima formation, remains an unsolved clinical problem after vascular interventions. A recent study has shown that CD40 signaling through TNF receptor associated factor 6 (TRAF6) plays a key role in neointima formation after carotid artery injury; however, underlying mechanisms are not clearly elucidated. Because neointima formation may vary significantly depending on the type of injury, we first assessed the effect of CD40 deficiency on neointima formation in 2 injury models, carotid artery ligation and femoral artery denudation injury. Compared with wild-type mice, CD40 deficiency significantly reduced neointima formation and lumen stenosis in two different models. Further, we investigated the mechanism by which CD40 signaling affects neointima formation after arterial injury. In wild-type mice, the expression levels of CD40, several TRAF proteins, including TRAF1, TRAF2, TRAF3, TRAF5, and TRAF6, as well as total NF-kB p65 and phospho-NF-kB p65, in the carotid artery were markedly upregulated within 3-7 days after carotid ligation. Deficiency of CD40 abolished the injury-induced upregulation of TRAFs including TRAF6 and NF-kB-p65 in the injured vessel wall. Further, CD40(-/-) mice showed a significant decrease in the recruitment of neutrophils (at 3, 7d) and macrophages (at 7, 21d) into injured artery; this effect was most likely attributed to inhibition of NF-kB activation and marked downregulation of NF-kB-related gene expression, including cytokines (TNFα, IL-1β, IL-6), chemokines (MCP-1), and adhesion molecules (ICAM-1, VCAM-1). Moreover, neutrophil recruitment in a model of thioglycollate-induced peritonitis is impaired in CD40-deficient mice. In vitro data revealed that CD40 deficiency blocked CD40L-induced NF-kB p65 nuclear translocation in leukocytes. Altogether, our data identified for the first time that CD40 is essential in the upregulation of TRAF6, NF-kB activation, and NF-kB-dependent proinflammatory genes in vivo. Our findings firmly established the role for CD40 in neointima formation in 2 distinct injury models.