gebhart/patrepeval huggingface dataset:
Comparison between a wireless dry electrode EEG system with a conventional wired wet electrode EEG system for clinical applications (2020)

Dry electrode electroencephalogram (EEG) recording combined with wireless data transmission offers an alternative tool to conventional wet electrode EEG systems. However, the question remains whether the signal quality of dry electrode recordings is comparable to wet electrode recordings in the clinical context. We recorded the resting state EEG (rsEEG), the visual evoked potentials (VEP) and the visual P300 (P3) from 16 healthy subjects (age range: 26-79 years) and 16 neurological patients who reported subjective memory impairment (age range: 50-83 years). Each subject took part in two recordings on different days, one with 19 dry electrodes and another with 19 wet electrodes. They reported their preferred EEG system. Comparisons of the rsEEG recordings were conducted qualitatively by independent visual evaluation by two neurologists blinded to the EEG system used and quantitatively by spectral analysis of the rsEEG. The P100 visual evoked potential (VEP) and P3 event-related potential (ERP) were compared in terms of latency, amplitude and pre-stimulus noise. The majority of subjects preferred the dry electrode headset. Both neurologists reported that all rsEEG traces were comparable between the wet and dry electrode headsets. Absolute Alpha and Beta power during rest did not statistically differ between the two EEG systems (p > 0.05 in all cases). However, Theta and Delta power was slightly higher with the dry electrodes (p = 0.0004 for Theta and p < 0.0001 for Delta). For ERPs, the mean latencies and amplitudes of the P100 VEP and P3 ERP showed comparable values (p > 0.10 in all cases) with a similar spatial distribution for both wet and dry electrode systems. These results suggest that the signal quality, ease of set-up and portability of the dry electrode EEG headset used in our study comply with the needs of clinical applications.
Influence of practice patterns on outcome among countries enrolled in the SYNTAX trial: 5-year results between percutaneous coronary intervention and coronary artery bypass grafting† (2017)

NCT00114972.
Les reseaux de relations de collaboration inter-entreprise: une analyse historique (1996)

Le concept de reseau suscite de puis plus d'une decennie beaucoup d'interet aupres des chercheurs et des praticiens de l'economie et de la gestion.
LPD silica coating of individual single walled carbon nanotubes (2005)

Single walled carbon nanotubes (SWNTs) have been coated with fluorine-doped silica by liquid phase deposition (LPD) using a silica–H2SiF6 solution and a surfactant stabilized solution of SWNTs. The coating of individual SWNTs versus small ropes is controlled by the choice of surfactant. Since the LPD reaction is performed close to the isoelectric point of the silica, some of the SiO2–SWNTs are fused together but the SWNTs remain individual in these composite structures. The SiO2–SWNTs have been characterized by SEM, TEM, Raman and IR spectroscopy, and XPS. Raman fluoresence is maintained even with coatings >50 nm. Using the relative intensity of the Raman G peak and the 8,3 SWNT fluorescence as a convenient measure of bundling, it may be shown that any decrease of fluoresence during growth is not due to changes in ionic strength or pH, as a consequence of addition of the LPD solution or the presence of HF as a side product in the deposition. The Raman D and G modes show no change in intensity, while the Fano line increases, both suggesting that no sidewall functionalization or proton adsorption of the SWNTs occurs during coating. The UV-visible-near infrared spectra shows a red shift in the first Van Hove transitions of the coated SWNTs inferring that the SWNTs in SiO2–SWNTs are in a more polarizable and inhomogeneous environment than that of surfactant solutions. Mats of SiO2–SWNT may be deposited onto silicon and gold substrates and through lithography may be patterned by etching off selected areas of the silica coating.
Solution-Processed Self-Assembled Nanodielectrics on Template-Stripped Metal Substrates (2015)

The coupling of hybrid organic-inorganic gate dielectrics with emergent unconventional semiconductors has yielded transistor devices exhibiting record-setting transport properties. However, extensive electronic transport measurements on these high-capacitance systems are often convoluted with the electronic response of the semiconducting silicon substrate. In this report, we demonstrate the growth of solution-processed zirconia self-assembled nanodielectrics (Zr-SAND) on template-stripped aluminum substrates. The resulting Zr-SAND on Al structures leverage the ultrasmooth (r.m.s. roughness <0.4 nm), chemically uniform nature of template-stripped metal substrates to demonstrate the same exceptional electronic uniformity (capacitance ∼700 nF cm(-2), leakage current <1 μA cm(-2) at -2 MV cm(-1)) and multilayer growth of Zr-SAND on Si, while exhibiting superior temperature and voltage capacitance responses. These results are important to conduct detailed transport measurements in emergent transistor technologies featuring SAND as well as for future applications in integrated circuits or flexible electronics.
Angiostatic Effect of CXCR3 Expressed on Choroidal Neovascularization (2012)

Purpose.: Several recent studies suggest that some chemokines/chemokine receptors are involved in choroidal neovascularization (CNV). CXCR3 was the focus of the present study because microarray analysis for murine laser-induced CNV model showed the increased expression of CXCR3. The purpose of this study was to evaluate the effect of CXCR3 on CNV. Methods.: Microarray analysis was performed for the mouse eyes with laser-induced CNV. CXCR3 expressions on the CNV were evaluated by immunohistochemistry and real-time RT-PCR. CNV was compared between CXCR3-deficient mice and wild-type mice, between mice treated with anti-CXCR3/anti-IP-10 neutralizing antibody and mice treated with control IgG. Macrophage recruitment into CNV was also investigated. Ocular expressions of vascular endothelial growth factor (VEGF), pigment epithelium-derived factor (PEDF), C-C chemokine ligand-2 (CCL2), and complement component-3 (C3) were evaluated by real-time PCR. Results.: Microarray analysis and real-time RT-PCR revealed the elevation of CXCR3 and IP-10 in laser-treated mouse eyes compared with control eyes. Immunohistochemistry showed CXCR3 expression on the endothelial cells of CNV. Laser-induced CNV of CXCR3-deficient mice was significantly larger, with greater leakage in fluorescein angiography, and with greater macrophage-infiltration compared with wild-type mice (P < 0.01). Intravitreal injection of anti-CXCR3/anti-IP-10 neutralizing antibody exacerbated CNV. The CCL2 expression in the laser-treated eyes of CXCR3-deficient mice was higher than in those of wild-type mice (P < 0.05), whereas VEGF, PEDF, and C3 showed no differences. Conclusions.: These results suggested that CXCR3 expressed on CNV could have an angiostatic effect on it.
Effects of saturation mutagenesis of the phage SP6 promoter on transcription activity, presented by activity logos (2000)

A full set of SP6 promoter variants with all possible single substitutions at positions -17 to +5 was constructed. Transcription activities of these variants were individually measured in vivo and in vitro to determine the contribution of each base pair to the promoter activity. The in vivo activity was measured indirectly by transcriptional interference of the replication of promoter-bearing plasmids. This activity depends most highly on residues -11, -9, -8, -7, and +1 (initiation site). All substitutions at -11, -9, -8, and -7 abolished formation of closed complexes, except for A-8C. These residues are involved in base-specific interactions with the polymerase, and the substitutions exhibit the same strong inhibition in vitro. In contrast, the in vitro activities of some other variants, measured on linearized templates, were different from those in vivo. Some variants at -13, -4, and -2, among others, showed exceptionally higher activities in vivo than in vitro, supporting the possibility that these residues are involved in postbinding steps, including template melting and bending. The A-3T variant showed much lower activity in vivo than in vitro, but it bound to the polymerase 2-fold more than the consensus sequence and is possibly involved in polymerase binding. A quantitative hierarchy of all the base pairs is graphically displayed by activity logos, revealing the energetic contribution of each base pair to the activity.
Cell-specific bioorthogonal tagging of glycoproteins (2022)

Altered glycoprotein expression is an undisputed corollary of cancer development. Understanding these alterations is paramount but hampered by limitations underlying cellular model systems. For instance, the intricate interactions between tumour and host cannot be adequately recapitulated in monoculture of tumour-derived cell lines. More complex co-culture models usually rely on sorting procedures for proteome analyses and rarely capture the details of protein glycosylation. Here, we report a strategy termed Bio-Orthogonal Cell line-specific Tagging of Glycoproteins (BOCTAG). Cells are equipped by transfection with an artificial biosynthetic pathway that transforms bioorthogonally tagged sugars into the corresponding nucleotide-sugars. Only transfected cells incorporate bioorthogonal tags into glycoproteins in the presence of non-transfected cells. We employ BOCTAG as an imaging technique and to annotate cell-specific glycosylation sites in mass spectrometry-glycoproteomics. We demonstrate application in co-culture and mouse models, allowing for profiling of the glycoproteome as an important modulator of cellular function.
Applications driving 3D integration and corresponding manufacturing challenges (2011)

Three dimensional (3D) semiconductor circuit integration has been an active area of research recently. Part of the driving force behind this interest has been applications. In this paper, we identify applications that drive 3D integration and point out the challenges they bring. In particular, we focus on through silicon via-based (TSV-based) 3D integration. TSV-based 3D integration opens up a new genre, and new opportunities for semiconductor integrated circuits. After a brief overview of TSV-based 3D technology overview, we identify driver applications that are dominant in this transition. We then point out challenges in the manufacturing area, i.e., thermal, reliability, EDA, cost, and test.
Anomalous Second-Order Nonlinear Optical Response of In-Plane Poled Glassy Polymers. Spectroscopic and Theoretical Support for the Importance of Charged Chromophore Aggregates (1997)

We report here measurements of the orientational and frequency dependence of the anomalously large second-order nonlinear optical (NLO) susceptibilities observed in guest-host DANS [4-(N,N-dimethylamino)-4'-nitrostilbene]/PMMA [poly(methyl methacrylate)] films poled in an 'in-plane' electrode configuration. The resonant response is sharply peaked (fwhm decreases by a factor of 4) in comparison to identical samples poled by standard corona field techniques. Additionally, these anomalous susceptibilities, which are oriented normal to the electric poling field, exhibit unusually strong features at long wavelengths where the linear absorption is low. We also report the first direct experimental EPR evidence for nitrogen-centered cation radicals, hence the creation of charged chromophores trapped in the polymeric matrix by charge injection from the poling electrodes. These observations are in qualitative agreement with the very large NLO response magnitudes and distinct spectral features predicted by sum-over-states perturbative calculations performed for positively charged centrosymmetric chromophore dimers and provide strong computational evidence that the observed anomalous NLO response is due to charged chromophore aggregates.
Synthesis and Characterization of the Dicopper(II)‐Containing 22‐Palladate(II)[CuII2PdII22PV12O60(OH)8]20− (2011)

A couple of coppers: Two CuII ions exhibit highly distorted cubic coordination and unexpectedly large magnetic exchange coupling in a discrete dicopper(II)-containing 22-palladate(II). The compound is isolated as the hydrated sodium salt Na20[CuII2PdII22PV12O60(OH)8]⋅58 H2O (1) in which the polyanion (see structure: Cu turquoise, Pd blue, O red balls, {PO4} purple tetrahedra) is the largest noble metalate reported to date. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Ketoconazole activates Cl- conductance and blocks Cl- and fluid absorption by cultured cystic fibrosis (CFPAC-1) cells. (1993)

The role of arachidonic acid metabolites in the regulation of apical cell membrane Cl- conductance and transepithelial transport of fluid and Cl- by cultured pancreatic cells from cystic fibrosis (CFPAC-1) and corrected (PAC-1) cell lines was evaluated by the use of inhibitors. CFPAC-1 cells did not exhibit an apical membrane Cl- conductance, absorbed Cl- and fluid, and did not respond to stimulation or inhibition of cAMP action. PAC-1 cells exhibited a cAMP-responsive apical Cl- conductance, which was blocked by indomethacin, a cyclooxygenase inhibitor. Ketoconazole, an epoxygenase inhibitor, had virtually no effects on PAC-1 cell Cl- conductance but caused CFPAC-1 cells to develop a cAMP-insensitive Cl- conductance, blocked Cl- and fluid absorption, and reduced transepithelial electrical resistance. Ketoconazole treatment effectively reversed the cystic fibrosis defect in these cultured cells.
Subarray-Processing Iterative SISO Multi-User Detection and Multi-Beam Directivity Control for Large-Scale Antenna Array in Quasi-Millimeter-Wave SDMA Systems (2013)

A subarray signal processing scheme is described for a large-scale two-dimensional analog-digital hybrid beamformer to be used in quasi-millimeter-wave-band mobile communication systems. Multiple analog phased arrays direct their respective beams to multiple users, enabling space-division multiple access (SDMA). An iterative soft-input soft-output (SISO) multi-user detector recovers multi-user signals from subarray output signals corrupted by inter-user interference (IUI). In addition, a phased-array directivity control algorithm is derived based on inter-subarray signal phase-difference estimation from inter-beam-interference (IBI)-cancelled subarray output signals. Simulation results demonstrate that our proposed scheme achieves reduced hardware complexity, IUI-resistant multi-user signal detection, and IBI-resistant multi-user-tracking phased-array directivity control.
Inelastic Neutron Scattering on Polymer Electrolytes for Lithium-Ion Batteries (2012)

The relationship between ion transport and polymer dynamics is central to the pursuit of solid polymer electrolytes for lithium batteries. This understanding is critical to achieve solid polymer electrolyte systems of sufficiently high ion conductivities. Solid polymer electrolytes are highly attractive from the perspective of their mechanical properties and low flammability compared to current electrolytes, however their ionic conductivities are typically an order of magnitude lower than the liquid electrolytes that are used today in commercial Li+ ion battery systems. Here we introduce inelastic neutron scattering (INS) as a tool to quantify the coupling between the local dynamics in the polymer electrolyte with the ion mobility through this ion transport media. INS technqiues are well suited for this task as they are primarily sensitive to the dynamics of the hydrogen rich polymer electrolyte and not the Li+ ions themselves. This is complimentary to dielectric or impedance measurements which in battery systems loaded with ionic charge carriers are primarily senstive to the dynamics if these ions; the impedance contribution from the organic electrolyte is usually overshadowed by the ions. The combination of INS and dielectric measurements provides the opportunity to directly correlate ion dynamics with the dynamics of the host electrolyte to better understand this complicated ion transport process. In this chapter we briefly introduce some of the basic INS techniques that can be used for these studies and review the current literature focused on understanding the dynamics in organic and polymer electrolytes for Li+ ion batteries.
Metal substitution in thermolysin: Catalytic properties of tungstate thermolysin in sulfoxidation with H2O2 (2002)

The catalytic Zn 2+ ion was extracted from thermolysin, which had been covalently bound to Eupergit C. The apo-enzyme incorporated the oxometallate anions MoO 4 2 , SeO 4 2 , and WO 4 2 with partial restoration of the proteolytic activity. Tungstate thermolysin was moderately active in the sulfoxidation of thioanisole by hydrogen peroxide, whereas its activity towards phenylmercaptoacetophenone, which was designed to bind well in the active site of thermolysin, was much higher.
Global Differences in Characteristics, Precipitants, and Initial Management of Patients Presenting With Acute Heart Failure (2020)

Data from REPORT-HF suggest that patients are similar across regions in many respects, but important differences in timing and type of treatment exist, identifying region-specific gaps in medical management that may be associated with patient outcomes.
17-MS/s 9-bit cyclic ADC with gain-assisted MDAC and attenuation-based calibration (2015)

A 17-MS/s 52.5-dB-SNDR 4.7-mW 0.045-mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> cyclic ADC has been achieved by the low-cost 0.18-μm CMOS. The only-26-dB gain of a simple op-amp has been successfully compensated by the proposed gain-assisted MDAC circuit and by the novel simple attenuation-based digital calibration. The prototype ADC chip has achieved the fastest speed, the smallest size and the best FOM among the high-speed (> 5 MS/s) highresolution (SNDR > 50 dB) low-cost-CMOS cyclic ADCs.
Broadened waveguide, low loss 1.5 μm InGaAsP/InP and 2 μm InGaAsSb/AlGaAsSb laser diodes (2002)

We demonstrate that free carrier absorption in cladding layers of long wavelength (/spl lambda/=1.5 /spl mu/m and /spl lambda/=2 /spl mu/m), separate confinement quantum well laser diodes limits the differential efficiency and output power for such lasers if their waveguide thickness is designed from the considerations of the maximum optical confinement factor for quantum wells. Broadening of the waveguide up to 1 /spl mu/m considerably increases laser efficiency and does not increase threshold for the lasers with low and moderate output losses. Broadened waveguide design provides the record output powers at continuous and quasi-continuous operation regimes.
Continuous-flow dielectrophoretic sorting of particles via 3D silicon electrodes featuring castellated sidewalls (2015)

Continuous-flow dielectrophoretic sorting of particles has been demonstrated using a simple microfluidic design incorporating 3D electrodes with castellated sidewalls. Two variations of the design have been fabricated, slightly differing in their sidewall and separation junction profiles, through a single-mask process on silicon-based platforms. These 3D silicon electrodes have shown the capacity to segregate polystyrene beads into distinct flow layers along the channel depth while delivering them to separate outlets through a downstream junction of a specific design. The utility of either structure has been showcased by sorting a mixture of 1 and 10 μm beads based on their size continuously at a velocity of 1.5 mm/s.
High Energy Density CNT/NaI Composite Cathodes for Sodium‐Ion Batteries (2018)

Abstract The Na‐iodine system has potential as a positive electrode in sodium‐ion batteries due to its fast reaction kinetics and high energy density. Here, the fabrication of a NaI‐loaded carbon nanotube (CNT) mat cathode is presented and the use of NaI as a Na‐ion battery cathode is reported for the first time. Freestanding electrodes show a capacity retention of 92% after 100 cycles at 100 mA h g −1 and a high specific energy density (≈473 W h kg −1 , second discharge basis vs Na metal) and small hysteresis (0.03 V). Adding a CNT mat interlayer between the NaI composite cathode and the separator, and fluoroethylene carbonate to the electrolyte significantly suppresses shuttling of active materials during cycling. Using ex situ X‐ray photoelectron spectroscopy and Raman data, an understanding of the relevant processes occurring during cycling of the CNT/NaI cathode is developed.
Expressed Sequence Tag (EST) Survey of Life Stages of the Potato Psyllid,Bactericera cockerelli, using 454 Pyrosequencing (2010)

The potato psyllid, Bactericera cockerelli (Sulc), is an insect pest of solanaceous plants and has recently become of interest because of its association with zebra chip, an immerging potato disease in the US. Genomic information on the potato psyllid is limited but could be used to develop novel management strategies for the insect and disease. To that end, cDNA libraries were prepared for the 5 instar and adult life stages. Structural and muscular, neurological and reproductive developmental processes, stress response and primary metabolism sequences were recovered. Metagenomic sequences aligning to microbial, viral and fungal symbionts or pathogens were also identified. Additionally, general housekeeping, life stage, and gender-specific targets were selected for RNAi-based knockdown experiments.
Abstract 3628: Serum Macrophage Inflammatory Protein 1 Beta as a Predictor for Cerebro-Cardiovascular Events in Hypertensive Patients (2006)

Background: We designed hospital-based cohort study to evaluate prognostic effects of NOn-invasive Atherosclerotic evaluation in Hypertension (NOAH study). Macrophage inflammatory protein-1β (MIP-1...
Efficient implementation of a geometry-based directional model for mobile radio channels (2003)

For the design and simulation of adaptive antenna systems, realistic and efficient spatial channel models are required. We investigate the so-called "geometry-based stochastic channel model" (GSCM), where the probability density function (PDF) of the location of the scatterers is prescribed. We analyse methods to efficiently implement GSCM, namely by nonuniform weighting of the scattering cross sections, and by combination with purely stochastic approaches. We then present various extensions of the model in urban environments, especially for wave guiding by street canyons.
Star vs long chain branching of poly(lactic acid) with multifunctional aziridine (2017)

A trifunctional aziridine linker, trimethylolpropane tris(2-methyl-1-aziridinepropionate) (TTMAP), was melt blended with linear poly(lactic acid) (PLA) to make (i) star-shaped PLA and (ii) long chain branched (LCB) PLA by utilizing both pyromellitic dianhydride (PMDA) and TTMAP. Mixing torque evolution during melt processing revealed high reactivity of TTMAP with the carboxyl end group on PLA and low reactivity of PMDA with the hydroxyl end group. Star-shaped PLA exhibited higher viscosity than linear PLA, but no strain hardening in extensional flow; while LCB PLA showed significant extensional hardening. The strain rate dependence of extensional hardening coefficient indicated that concentration of LCB molecules in LCB PLA is low and the possible topological chain structure of those molecules is H-shaped. Unlike current methods used to branch PLA, (e.g., free radical chemistry or the use of an epoxy functional oligomers), our branching strategy produced strain hardening with less increase in shear viscosity. The topological structures of LCB chains by free radical chemistry and epoxy functional oligomers are also discussed.