gebhart/patrepeval huggingface dataset:
Carbon nanotube tips for thermomechanical data storage (2003)

We report the demonstration of thermomechanical data storage in a poly(methylmethacrylate) film using a multiwalled carbon nanotube (MWCNT) tip. Indentation densities of &amp;gt;250 Gbits/in2 are achieved. The power efficiency of indent writing with MWCNT tips is found to be higher than that of conventional silicon tips owing to better heat transfer at the tip–polymer interface.
New class of uranium oxide catalysts for the oxidative destruction of volatile organic compounds in the vapour phase (1997)

In recent years the implementation of stricter legislation limiting the permitted emission levels of aerial volatile organic compounds effluent has imposed increased costs on many industries. The challenge for industry has been to effectively control these emissions with minimum economic burden. One of the main effluent treatment technologies which has been employed for VOC abatement is oxidative catalytic destruction. In this study uranium oxide based catalysts have been investigated for the oxidative destruction of VOCs to carbon oxides and water. The catalysts have been tested for the destruction of a range of organic compounds at space velocities up to 70,000 h-1. The uranium based catalysts include both supported, unsupported and transition metal doped systems. Reactivity studies have shown that destruction efficiencies greater than 99 can be achieved over the appropriate uranium based catalyst in the temperature range of 150-450Â°C. The organic compounds investigated include benzene, butylacetate, cyclohexanone, butane and chlorobenzene. In the case of non-halogenated compounds the reaction products are carbon oxides and water, whilst the reaction of chlorobenzene also produces HCl. In the case of the destruction of chlorobenzene, no deactivation of the uranium based catalyst was observed. The observed reactivity and lifetime of the uranium based catalyst systems show there is good potential for the application of these materials in commercial VOC abatement systems.
Hyaluronic acid-based hydrogels with independently tunable mechanical and bioactive signaling features (2019)

Extracellular matrix provides critical signaling context to resident cells through mechanical and bioactive properties. To realize the potential of tissue engineering and regenerative medicine, biomaterials should allow for the independent control of these features. This study investigates a hydrogel system based on thiol-modified hyaluronic acid (HA-S) and polyethylene glycol diacrylate (PEGDA). The mechanical properties of HAS-PEGDA are dictated by two cytocompatible crosslinking reactions that occur at distinct time points: a rapid, Michael-type nucleophilic addition reaction between HA-thiols and PEG-acrylates and a prolonged maturation of disulfide crosslinks from remaining thiols. It is hypothesized that these reactions would enable the independent tuning of the mechanical and bioactive features of HAS-PEGDA. Rheological studies confirmed that initial gelation reached completion by 1 day, at which point the shear modulus was proportional to the concentration of PEGDA. Over time, the shear modulus evolved dramatically, and final stiffness depended on the availability of HA-thiols. The addition of PEG-monoacrylate (PEGMA) after the initial gelation occupied a percentage of remaining thiols to prevent disulfide crosslinking, decreasing the steady-state stiffness in a dose-dependent manner. A fraction of the PEGMA was then replaced with acrylated peptide ligands to introduce specific bioactivity to the otherwise non-cell-adhesive network. The degree of latent stiffening was controlled by the total amount of peptide-PEGMA, while adhesivity was tuned with the balance of bioactive and inactive peptides. The functional effects of the tunable mechanical and bioadhesive ligand properties were confirmed with assays of cell adhesion and morphology.
Adaptively extendable multi-stage spiking neural network (2020)

Recently, a significant improvement has been observed in the recognition rate in deep neural networks (DNNs). However, as the number of layers increases, additional computations and significant power consumption are required by the DNN. In this study, we propose a novel spiking neural network (SNN) that exhibits high recognition rate and reduced computational cost. If the reliability of the output of the current neural network (NN) is decided to be low, we feed forward the result to the input of the next NN. We use backpropagation learning algorithm to train the component NN. Since most of the decisions are made in the early stage, the proposed method shows approximately 83% reduction of the computational cost compared with the conventional SNN with the same recognition rate.
Perinadine A, a Novel Tetracyclic Alkaloid from Marine‐Derived Fungus Penicillium citrinum. (2006)

A novel tetracyclic alkaloid, perinadine A (&lt;b&gt;1&lt;/b&gt;), was isolated from the cultured broth of the fungus &lt;i&gt;Penicillium citrinum&lt;/i&gt;, which was separated\nfrom the gastrointestine of a marine fish, and the structure was elucidated on the basis of spectroscopic data including 2D NMR spectra.\nBiogenetically, perinadine A (&lt;b&gt;1&lt;/b&gt;) may be derived from citrinin (&lt;b&gt;4&lt;/b&gt;), a well-known mycotoxin, and a scalusamide A-type pyrrolidine alkaloid.
Circularly polarised multiple beam antenna for satellite applications (2017)

This paper presents a novel circularly polarised Ku-band multiple beam antenna based on a quasi-optical beamformer and a wideband reflection polarizer conformally deployed along a cylindrical parabolic reflector for satellite applications. By virtue of the wide scanning capability of the beamformer and the wide band and angularly stable response of the curved polarising reflector we demonstrate multibeam capability in circular polarization up to ±18° for a wide Ku band (10-14.5 GHz) with axial ratio below 2 dB. Manufacturing and testing methods are discussed. A breadboard of the multibeam reflector antenna has been fabricated and tested demonstrating very good performance that matches the simulated results.
Tetrathia[7]helicene Phosphorus Derivatives: Experimental and Theoretical Investigations of Electronic Properties, and Preliminary Applications as Organocatalysts (2016)

Abstract Combined experimental and theoretical study on the electronic characteristics of tetrathiahelicene (7‐TH) alkyl and aryl phosphorus derivatives, including phosphanes, phosphine–borane complexes, phosphine oxides, and phosphine–selenides, is described. The collected data give useful information on the σ‐donor ability of the phosphorus atoms, which mainly depends on the aryl or alkyl nature of the substituents at the phosphorus atom. Electrochemical investigations provide the relationships between the electronic and structural properties, and quantum chemical calculations show a clear dominance of the 7‐TH scaffold on the electronic properties of all investigated molecules. Finally, different electronic and steric properties of 7‐TH phosphanes strongly influenced their catalytic behavior, for example, as Lewis base organocatalysts in typical [3+2] annulation reactions.
CVD Growth and Characterization of 4H-SiC Epitaxial Film on (11-20) As-Cut Substrates (2005)

Thick epilayers up to 60 µm have been grown on ) 0 2 11 ( face SiC substrates at a growth rate of 15 µm/hr by chemical vapor deposition (CVD). The epilayer surface is extremely smooth with a RMS roughness of 0.6 nm for a 20µm×20µm area. Threading screw and edge dislocations parallel to the c-axis are present in the ) 0 2 11 ( substrate; however, they do not propagate into the epilayer. The I-V characteristics of the Schottky diodes on this face were studied. Basal plane (0001) dislocations with a density of ~105 cm-2 were found in the ) 0 2 11 ( epilayers by molten KOH etching and electron beam induced current (EBIC) mode of the scanning electron microscope (SEM).
Structure-activity studies on antidepressant 2,2-diarylethylamines (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure-activity studies on antidepressant 2,2-diarylethylaminesBruce E. Maryanoff, Samuel O. Nortey, and Joseph F. GardockiCite this: J. Med. Chem. 1984, 27, 8, 1067–1071Publication Date (Print):August 1, 1984Publication History Published online1 May 2002Published inissue 1 August 1984https://pubs.acs.org/doi/10.1021/jm00374a022https://doi.org/10.1021/jm00374a022research-articleACS PublicationsRequest reuse permissionsArticle Views242Altmetric-Citations16LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Identification of the Clinical Development Candidate MRTX849, a Covalent KRASG12C Inhibitor for the Treatment of Cancer (2020)

Capping off an era marred by drug development failures and punctuated by waning interest and presumed intractability toward direct targeting of KRAS, new technologies and strategies are aiding in the target's resurgence. As previously reported, the tetrahydropyridopyrimidines were identified as irreversible covalent inhibitors of KRAS<sup>G12C</sup> that bind in the switch-II pocket of KRAS and make a covalent bond to cysteine 12. Using structure-based drug design in conjunction with a focused in vitro absorption, distribution, metabolism and excretion screening approach, analogues were synthesized to increase the potency and reduce metabolic liabilities of this series. The discovery of the clinical development candidate <b>MRTX849</b> as a potent, selective covalent inhibitor of KRAS<sup>G12C</sup> is described.
Liquid Crystalline Dendrimers (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
The small-animal radiation research platform (SARRP): dosimetry of a focused lens system (2007)

A small animal radiation platform equipped with on-board cone-beam CT and conformal irradiation capabilities is being constructed for translational research. To achieve highly localized dose delivery, an x-ray lens is used to focus the broad beam from a 225 kVp x-ray tube down to a beam with a full width half maximum (FWHM) of approximately 1.5 mm in the energy range 40-80 keV. Here, we report on the dosimetric characteristics of the focused beam from the x-ray lens subsystem for high-resolution dose delivery. Using the metric of the average dose within a 1.5 mm diameter area, the dose rates at a source-to-surface distance (SSD) of 34 cm are 259 and 172 cGy min(-1) at 6 mm and 2 cm depths, respectively, with an estimated uncertainty of +/-5%. The per cent depth dose is approximately 56% at 2 cm depth for a beam at 34 cm SSD.
Active Frequency Selective Surfaces Using Incorporated PIN Diodes (2008)

In this paper, active frequency selective surfaces (FSS) having a squared aperture with a metal plate loading are described. Active FSS elements using switched PIN diodes are discussed with an equivalent circuit model. A unit cell consists of a square aperture element with metal island loading and one PIN diode placed at the upper gap, considering the vertical polarization. The electromagnetic properties of the active FSS structure are changed by applying dc bias to the substrate, and they can be estimated by the equivalent circuit model of the FSS structure and PIN diode. This active FSS design enables transmission to be switched on or off at 2.3GHz, providing high transmission when the diodes are in an off state and high isolation when the diodes are on. The equivalent circuit model in the structure is investigated by analyzing transmission and reflection spectra. Measurements on active FSS are compared with numerical calculations. The experimentally observed frequency responses are also scrutinized.
Interleukin 5 Plays an Essential Role in Elicitation of Contact Sensitivity through Dual Effects on Eosinophils and B-1 Cells (2006)

We conclude that IL-5-dependent activation of eosinophils and B-1 cells is necessary for induction and elicitation of CS. These findings provide a new insight into complicated mechanisms of CS elicitation and suggest a novel role of IL-5 in the regulation of immune responses.
Pulsed voltage pre-breakdown observations on silicon in vacuum (2002)

The flashover process consists of three phases: phase i is characterized by the presence of displacement, ohmic, or space-charge-limited (SCL) current; phase ii represents partial collapse in the applied voltage accompanied by luminosity and an increase in current; and phase iii, or flashover, consists of complete voltage collapse, rapid rise in current, and intense luminosity. The existence of low-level emission in the ultraviolet-visible range during phase i in the presence of well-established SCL current is shown. The luminosity exhibits an increase in intensity just prior to the initiation of phase ii, thus indicating the onset of device failure as evidenced by partial voltage collapse. The inception voltage for phase i luminosity shows a correlation with the onset of phase ii and iii processes, but no correlation with the conditioned flashover voltage is observed. Sample preparation can significantly increase the luminosity inception voltage.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
A Novel Technique to Create Energy-Efficient Contexts for Reconfigurable Logic (2007)

High power consumption is a constraining factor for the growth of programmable logic devices. We propose two techniques in order to reduce power consumption. The first is a technique for creating contexts. This technique uses data-dependent circuits and wire sharing between contexts. The second is a technique for switching the contexts. In this paper, we evaluate the capability of the two techniques to reduce power consumption using a multi-context logic device. As a result, as compared with the original circuit, our multi-context circuits can reduce the power consumption by 9.1% on an average and by a maximum of 19.0%. Furthermore, applying our resource sharing technique to these circuits, we achieved a reduction of 10.6% on an average and a maximum reduction of 18.8%.
A Reconfigurable CMOS Power Amplifier based on Switched Power Cells for 3GPP LTE Applications (2012)

International audience
Calculation of excited-state geometries via the time-dependent theory of resonance Raman spectroscopy: application to dirhodium tetraacetate complexes of the type Rh2(O2CCH3)4(MPh3)2, M = phosphorus, arsenic, or antimony, at resonance in each case with the lowest A2u excited state (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCalculation of excited-state geometries via the time-dependent theory of resonance Raman spectroscopy: application to dirhodium tetraacetate complexes of the type Rh2(O2CCH3)4(MPh3)2, M = phosphorus, arsenic, or antimony, at resonance in each case with the lowest A2u excited stateKyeong Sook Shin, Robin J. H. Clark, and Jeffrey I. ZinkCite this: J. Am. Chem. Soc. 1989, 111, 12, 4244–4250Publication Date (Print):June 1, 1989Publication History Published online1 May 2002Published inissue 1 June 1989https://pubs.acs.org/doi/10.1021/ja00194a015https://doi.org/10.1021/ja00194a015research-articleACS PublicationsRequest reuse permissionsArticle Views108Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Leakage Current Mechanisms and Estimation in Memories and Logic (2011)

Contents 7.1 Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .240 7.2 Leakage Current Mechanisms . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .240
Mixed‐lineage eosinophil/basophil crisis in MDS: a rare form of progression (2008)

Mixed basophil/eosinophil crisis may develop in patients with MDS but is an extremely rare event.
The FAIR Cookbook - the essential resource for and by FAIR doers (2022)

Nowadays, the FAIR Principles guide data policy actions and professional practices in the public and private sectors. However, despite such global endorsements, the FAIR Principles are aspirational, remaining elusive at best, and intimidating at worst. To address the lack of practical guidance, and help with capability gaps, we developed the FAIR Cookbook, an online resource of hands-on recipes for “FAIR doers” in the Life Sciences. Launched in 2020, and created by researchers and data managers professionals in academia, pharmas and information service industries, the <strong>FAIR Cookbook</strong> covers the key steps in a FAIRification journey, the levels and indicators of FAIRness, the maturity model, the technologies, the tools and the standards available, as well as the skills required, and the challenges to achieve and improve data FAIRness. In this pre-print, we present the FAIR Cookbook, its creation and content, its value, use and adoptions, as well as the participatory process, collaborative plans for sustainability, and its adoption. The full list of FAIR Cookbook Recipes’ Authors is here.<em> </em>
ON-LINE TRANSDUCER COMPOSITION AND SMOOTHED LANGUAGE MODEL INCORPORATION (2002)

This paper presents and evaluates our recent efforts on ef­ ficient decoding for Large Vocabulary Continuous Speech Recognit ion in the framework of Weighted Finite State Transducers. We evaluat e on-the-fty transducer compo­ sition for reduced memory consumption combined with weight smearing for a more time-synchron ous language model incorporation. It turns out that in the on-li ne com­ position mode weight smoothing within the static part of the network is even more beneficial on run-time to accu­ racy ratio than in the fully precompiled case. Evaluations are carried out on a state-of-the-art recognition system of 10k words, cross-word triphone acoustie models and trigram language model. In this scenario, the Viterbi-search is car­ ried out full y time-synchro nously in only a single pass. The combination of on-the-fly network composition with only the unigram part of the language model smoothly compiled into the network achieves a remarkably good run-time to accuracy ratio with only moderate memory requirements.
Differences in outcome of the interaction between Cryptococcus neoformans glucuronoxylomannan and human monocytes and neutrophils (2003)

Disseminated infections by the opportunistic yeast Cryptococcus neoformans are characterized by accumulation in tissues of glucuronoxylomannan (GXM), the major component of the capsular polysaccharide. We investigated binding, uptake, and disposal of GXM by peripheral blood neutrophils and monocytes, and the effect of GXM uptake on phagocytic cell function. GXM was efficiently bound and internalized by both types of phagocytic cells, with maximal loading at 50 microg/ml, a GXM concentration found in serum and cerebrospinal fluid of some cryptococcosis patients. However, substantial differences were noted in the kinetics for uptake by macrophages and neutrophils. Whereas neutrophils rapidly ingested limited amounts of GXM and then expelled or degraded it after 1 h of incubation, macrophages demonstrated continuous intracellular accumulation for up to 1 week of incubation. Accumulation of GXM by neutrophils was accompanied by reduced anticryptococcal activity, suggesting one more mechanism for virulence enhancement by the major capsular component of C. neoformans.
INHIBITION OF COMPLEMENT-MEDIATED HEMOLYSIS IN GEL BY RHEUMATOID FACTORS (2009)

When subjected to a hemolysis in gel (HIG) assay for the detection of complement deficiency, 9 of 37 sera from patients with classical rheumatoid arthritis produced impaired lysis of sensitized sheep erythrocytes. All sera were normal in a test for the alternative pathway and no major abnormalities were found within the complement system. Using a two-step HIG technique, with guinea-pig serum as the complement source, all sera were shown to inhibit lysis of sheep erythrocytes sensitized with rabbit IgG. Lysis of IgM-coated erythrocytes was not inhibited. The agglutination titers in a Waaler-Rose test, and the areas of inhibition in the two-step HIG assay with IgG-sensitized erythrocytes, were correlated (r = 0.80, p less than 0.001). Absorption of serum with rabbit IgG coupled to Sepharose 4B, reduced the capacity to inhibit immune hemolysis. The eluate from IgG-Sepharose contained rheumatoid factors and also inhibited immune hemolysis. The findings suggested that rheumatoid factors in serum were responsible for inhibition in the HIG assays used.
Amplificateur de puissance 5G reconfigurable d'un mode Doherty à un mode équilibré sur la bande 24-31 GHz en CMOS 28nm FD-SOI (2022)

International audience
Supplementary Figure 5 from Immunologic Recognition of a Shared p53 Mutated Neoantigen in a Patient with Metastatic Colorectal Cancer (2023)

&lt;p&gt;Supplementary Figure 5&lt;/p&gt;
Source coding for decentralized estimation systems (1990)

Parameter estimation in decentralized systems with distributed processors is considered. The authors restrict the local processors to be quantizers and consider the optimal design of the system to minimize the estimation error. They derive the necessary conditions of the optimal system based on different distortion functions. In particular, they show that using Fisher's information as a distortion function can simplify the design of quantizers. An expression for the asymptotic quantization error of scalar quantizers is also derived. Numerical results show that using Fisher's information can simplify the design and achieve good performance.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>