gebhart/patrepeval huggingface dataset:
Computation of the Hankel transform using projections (1980)

In this paper two new algorithms for computing an nth-order Hankel transform are proposed. The algorithms are based on characterizing a circularly symmetric function and its two-dimensional Fourier transform by a radial section and interpreting the Hankel transform as the relationship between the radial section in the two domains. By utilizing the property that the projection of a two-dimensional function in one domain transforms to a radial section in the two-dimensional Fourier transform or inverse Fourier transform domain, several efficient procedures for computing the Hankel transform exploiting the one-dimensional FFT algorithm are suggested.
A whole-grain cereal-rich diet increases plasma betaine, and tends to decrease total and LDL-cholesterol compared with a refined-grain diet in healthy subjects (2011)

Epidemiological studies have repeatedly found that whole-grain (WG) cereal foods reduce the risk of several lifestyle-related diseases, though consistent clinical outcomes and mechanisms are elusive. To compare the effects of a WG-rich diet with a matched refined-grain (RG) diet on plasma biomarkers and bowel health parameters, seventeen healthy subjects (eleven females and six males) completed an exploratory cross-over study with a 2-week intervention diet based on either WG- or RG-based foods, separated by a washout of at least 5 weeks. Both diets were the same except for the use of WG (150 g/d) or RG foods. Subjects undertook a 4 h postprandial challenge on day 8 of each intervention diet. After 2 weeks, the WG diet tended to decrease plasma total and LDL-cholesterol (both P = 0·09), but did not change plasma HDL-cholesterol, fasting glucose, C-reactive protein or homocysteine compared with the RG diet. Plasma betaine and alkylresorcinol concentrations were elevated after 1 week of the WG diet (P = 0·01 and P < 0·0001, respectively). Clostridium leptum populations in faeces were increased after the WG diet, along with a trend for decreased faecal water pH (P = 0·096) and increased stool frequency (P < 0·0001) compared with the RG diet. A short controlled intervention trial with a variety of commercially available WG-based products tended to improve biomarkers of CVD compared with a RG diet. Changes in faecal microbiota related to increased fibre fermentation and increased plasma betaine concentrations point to both fibre and phytochemical components of WG being important in mediating any potential health effects.
Formação em psiquiatria forense: aspectos comparativos para uma reflexão sobre o modelo Português. (2011)

Forensic psychiatry has experienced a significant development in the last few decades. Several mechanisms underlie this shift, including deinstitutionalization of mental health patients and extraordinary progress in neurosciences, imaging technologies and psychology, just no name a few. This development has put in evidence specific needs for training and education. A review and comparison of forensic psychiatry training in several European countries, U.S.A. and Brazil is made.A mixed approach was used, including a) systematic literature review (Pubmed search, 1989-2009) and cross-reference search and inclusion; b) specific online sites search (e.g. medical associations or scientific societies responsible for forensic psychiatry training); c) direct contact with psychiatrists and forensic psychiatrists.Forensic psychiatry training is still a heterogeneous field. While not all countries have specialization, subspecialization or competency certification in forensic psychiatry, there has been, however, a definite shift towards its individuation as a specific technico-scientific area. This contributes to an improvement in quality standards and promotes research. Notwithstanding, forensic training in general adult and child psychiatry's residencies should continue to be strengthened as it is likely that most forensic activities will remain at their care in the near future.
Electrochemical Synthesis of Sodium Peroxycarbonate at Boron-Doped Diamond Electrodes (2003)

An electrochemical method for the preparation of sodium peroxycarbonate at boron-doped diamond anodes has been described. Effects of experimental conditions such as current density, electrolyte concentration and anode materials on the formation of sodium peroxycarbonate have been investigated. The maximum current efficiency for producing sodium peroxycarbonate was found to be 82% at a current density of 0.05 A cm−2 after 30 min of electrolysis in a solution of 1 M The minimum energy consumption was found to be 2.2 Wh g−1 at a current density of 0.05 A cm−2. The X-ray powder diffraction pattern was obtained in order to identify the products. The products were also analyzed using TG/DTA in order to determine the melting point. © 2003 The Electrochemical Society. All rights reserved.
Influence of High Contents of Silver Nanoparticles on the Physical Properties of Poly(Vinylidene Fluoride) (2007)

Silver (Ag) nanoparticles were incorporated into poly(vinylidene fluoride) (PVDF) up to 90 wt% (15.3 vol%) via melt mixing. The addition of Ag nanoparticles slightly increased the crystallization temperature and heat of crystallization of PVDF by 1.2°C and 5.1 J/g at 90 wt% loading, respectively. In the thermal degradation behaviors, high contents of Ag nanoparticles more than 50 wt% induced a negative effect on the thermal stability of the matrix by decreasing the onset temperature of the degradation as much as 40°C. Thermal conductivity was slightly increased with Ag content up to 5 wt%, but further addition of Ag induced a notable increase because of the high thermal conductivity of Ag nanoparticles. In the WAXD (Wide Angle X-ray Diffraction) patterns, all the samples presented only α-phase crystal regardless of Ag loading. Both tensile strength and elongation at break were decreased from 5 wt% loading with increasing Ag content.
The primary structure of rabbit and rat prealbumin and a comparison with the tertiary structure of human prealbumin. (1985)

The primary structures of rabbit and rat prealbumin have been determined. The amino acid sequence of rabbit prealbumin was determined by analyses of peptides obtained by trypsin and Staphylococcus aureus protease digestions. The rat prealbumin sequence was deduced by analyses of tryptic peptides as well as by nucleotide sequencing of cDNA clones. Both amino acid sequences contain 127 amino acid residues, the same as human prealbumin. Pairwise comparisons show that the three sequences are more than 80% identical. All three prealbumins were found to display significant sequence homology with human thyroxine-binding globulin. A comparison of the primary structures of the prealbumins with the tertiary structure of human prealbumin shows that amino acid replacements are preferentially located at the surface of the molecule and in the loops connecting the beta-strands. The locations of the replacements are discussed as regards the different molecular interactions in which prealbumin is involved.
P-138 Sustained Efficacy in Patients with Ulcerative Colitis Treated with Adalimumab (2013)

The efficacy and safety of adalimumab (ADA) for induction and maintenance of remission in patients with moderately to severely active ulcerative colitis (UC) was demonstrated in ULTRA 2.1 Sustained efficacy at weeks 8, 32, and 52 with ADA treatment has not been reported. Adults with UC for >3 months (Mayo score 6–12; endoscopy subscore 2–3) failing corticosteroid or immunosuppressant therapy were randomised to placebo (PBO) or ADA (160/80 mg, week 0/2; 40 mg every other week [eow] from week 4). Anti-TNF-exposed patients were eligible. Patients with inadequate response could move to open-label (OL) ADA (40 mg eow) from week 12. Endoscopy was performed and full Mayo score was calculated at weeks 8, 32, and 52, using the worst rectal bleeding and stool frequency scores from the previous 3 days. Remission (Mayo score ≤2, no subscore >1), response (Mayo score decrease ≥3 points and ≥30% from baseline, and rectal bleeding subscore ≤1 or decreased by ≥1), and mucosal healing (endoscopy subscore ≤1) were assessed at each timepoint. The proportion of patients with efficacy at all 3 timepoints was determined (non-responder imputation: patients who moved to OL ADA or with missing data were considered not to have achieved the endpoint). Results were compared for ADA- versus PBO-treated patients (ITT, Cochran-Mantel-Haenszel test,) and in subgroups by prior anti-TNF use (chi-squared or Fisher’s exact test). ADA-treated patients were significantly more likely than PBO-treated patients to achieve sustained remission, response, and mucosal healing (Table). Anti-TNF-naïve ADA-treated patients were significantly more likely than PBO-treated patients to achieve each of the sustained efficacy endpoints. Anti-TNF-exposed ADA-treated patients had significantly greater rates of response, while remission or mucosal healing rates were numerically but not statistically greater, compared with PBO-treated patients. In ULTRA 2, ADA treatment resulted in statistically significantly greater rates of sustained efficacy at weeks 8, 32, and 52 than PBO treatment, with anti-TNF-naïve patients deriving the largest treatment benefit. Reference: 1. Sandborn WJ, et al. Gastroenterology. 2012:142.
Multiple-view geometry for image-based modeling (2004)

This course presents the state of the art in multiple-view geometry, including methods and algorithms for reconstructing 3-D geometric models of scenes from video or photographs. This course is based on a novel approach to multiple-view geometry that only requires linear algebra, as opposed to more involved projective and algebraic geometry that most current methods employ. This new approach aims to make image-based modeling techniques accessible to a larger audience compared to existing ones. The presentations will be based on a recent Springer-Verlag textbook on 3D vision (coauthored by the course organizers). Matlab code for the algorithms will be made available at the book website.
Glucose 6-Phosphate Dehydrogenase from Trypanosomes: Selectivity for Steroids and Chemical Validation in Bloodstream Trypanosoma brucei (2021)

Glucose 6-phosphate dehydrogenase (G6PDH) fulfills an essential role in cell physiology by catalyzing the production of NADPH<sup>+</sup> and of a precursor for the de novo synthesis of ribose 5-phosphate. In trypanosomatids, G6PDH is essential for in vitro proliferation, antioxidant defense and, thereby, drug resistance mechanisms. So far, 16α-brominated epiandrosterone represents the most potent hit targeting trypanosomal G6PDH. Here, we extended the investigations on this important drug target and its inhibition by using a small subset of androstane derivatives. In <i>Trypanosoma cruzi</i>, immunofluorescence revealed a cytoplasmic distribution of G6PDH and the absence of signal in major organelles. Cytochemical assays confirmed parasitic G6PDH as the molecular target of epiandrosterone. Structure-activity analysis for a set of new (dehydro)epiandrosterone derivatives revealed that bromination at position 16α of the cyclopentane moiety yielded more potent <i>T. cruzi</i> G6PDH inhibitors than the corresponding β-substituted analogues. For the 16α brominated compounds, the inclusion of an acetoxy group at position 3 either proved detrimental or enhanced the activity of the epiandrosterone or the dehydroepiandrosterone derivatives, respectively. Most derivatives presented single digit μM EC<sub>50</sub> against infective <i>T. brucei</i> and the killing mechanism involved an early thiol-redox unbalance. This data suggests that infective African trypanosomes lack efficient NADPH<sup>+</sup>-synthesizing pathways, beyond the Pentose Phosphate, to maintain thiol-redox homeostasis.
Sequential Parametric Optimization for Rate-Splitting Precoding in Non-Orthogonal Unicast and Multicast Transmissions (2022)

This paper investigates rate-splitting (RS) precoding for non-orthogonal unicast and multicast (NOUM) transmissions using fully-digital and hybrid precoders. We study the nonconvex weighted sum-rate (WSR) maximization problem subject to a multicast requirement. We propose FALCON, an approach based on sequential parametric optimization, to solve the aforementioned problem. We show that FALCON converges to a local optimum without requiring judicious selection of an initial feasible point. Besides, we show through simulations that by leveraging RS, hybrid precoders can attain nearly the same performance as their fully-digital counterparts under certain specific settings.
Geodesic lens: new designs for illumination engineering (2006)

A novel waveguide-optical integrator is introduced for applications to LEDs. The concept is based upon a Kohler illuminator made of Luneburg lenses. Typical Kohler illuminators are formed by pairs of thin lenses, and perform badly when the paraxial approximation is rough, i.e., when the angular span of the incoming rays is wide. In contrast, the new illuminator performs ideally for angular spans up to 90° (±45°), and has only a 3% loss for a 180° angular span. In general such an illuminator cannot be made in 3D, because adjacent Luneburg lenses overlap. It can, however, be implemented in planar optics, by using Rinehart geodesic lenses. This waveguide device has application in illumination engineering as a light mixer, particularly for LEDs. Another light mixer using a combination of two kaleidoscopes with a geodesic lens is also presented. Irradiance at the exit of a kaleidoscope has good light mixing if the kaleidoscope is long enough, but the intensity is never well mixed, irrespective of the length. Inserting a Rinehart geodesic lens produces a 90-degree phase-space rotation of the rays, i.e., it exchanges irradiance and intensity. An further kaleidoscope assures complete mixing in both irradiance and intensity.
Robust and Computationally Lightweight Autonomous Tracking of Vehicle Taillights and Signal Detection by Embedded Smart Cameras (2015)

An important aspect of collision avoidance and driver assistance systems, as well as autonomous vehicles, is the tracking of vehicle taillights and the detection of alert signals (turns and brakes). In this paper, we present the design and implementation of a robust and computationally lightweight algorithm for a real-time vision system, capable of detecting and tracking vehicle taillights, recognizing common alert signals using a vehicle-mounted embedded smart camera, and counting the cars passing on both sides of the vehicle. The system is low-power and processes scenes entirely on the microprocessor of an embedded smart camera. In contrast to most existing work that addresses either daytime <bold xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><i>or</i></b> nighttime detection, the presented system provides the ability to track vehicle taillights <bold xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><i>and</i></b> detect alert signals regardless of lighting conditions. The mobile vision system has been tested in actual traffic scenes and the results obtained demonstrate the performance and the lightweight nature of the algorithm.
Modelling of Irreversible Deformation near the Tip of a Crack in a Porous Domain Containing Oil and Gas (2014)

Summary Thermomechanical processes observing in deformable solids under intensive dynamic or quasi-static loadings consist of coupled mechanical, thermal and fracturing stages. The fracturing processes involve formation, motion and interaction of defects in crystals, phase transitions, breaking of bonds between atoms, accumulation of micro-structural damages (pores, cracks), etc. Irreversible deformations, zones of adiabatic shear micro-fractures are caused by these processes. A dynamic fracturing is a complicated multistage process, which includes appearance, evolution and confluence of micro-defects and formation of embryonic micro-cracks, pores that can grow and lead to the breaking-up of bodies with formation of free surfaces. This results in a need to use more advanced mathematical and numerical techniques. This talk presents modeling of irreversible deformation near the tip of a crack in a porous domain containing oil and gas during the hydraulic fracturing process. The governing equations for a porous domain containing oil and gas are based on constructing mathematical model of thermo-visco-elasto-plastic media with micro-defects (micro-pores) filled with another phase (e.g., oil or/and gas). The micropores can change their size during the process of dynamical irreversible deformation. The existing pores can expand or collapse. The model was created by using the fundamental thermodynamic principles and, therefore, it is a thermodynamically consistent model. All the processes (i.e., irreversible deformation, fracturing, micro-damaging, heat transfer) within a porous domain are strongly coupled. Therefore, explicit normalized-corrected meshless method is used to solve the resulting governing PDEs. The flexibility of the proposed technique allows running efficiently using a great number of micro- and macro-fractures. The results are presented, discussed and future studies are outlined.
A Review of the Ecology, Genomics, and Stress Response ofListeria innocuaandListeria monocytogenes (2012)

Listeria monocytogenes is a Gram-positive foodborne pathogen responsible for a severe disease occurring in immuno-compromised populations. Foodborne illness caused by L. monocytogenes is a serious public health concern because of the high associated mortality. Study of the closely related, but nonpathogenic Listeria innocua has accounted for a better understanding of the behavior of L. monocytogenes in environments beyond the laboratory. Traditionally, the ecological co-habitation, genomic synteny, and physiological similarity of the two species have supported use of L. innocua for predicting the behavior of L. monocytogenes in farm and food processing environments. However, a careful review of the current literature indicates that in a given situation it may not be prudent to use L. innocua as a surrogate for L. monocytogenes without prior confirmation of their similar phenotypes, as an increasing number of studies have arisen demonstrating differences in L. monocytogenes and L. innocua stress response, and furthermore, there are differences among the L. monocytogenes subgroups. Future research should take into consideration that multiple surrogates might be required to accurately model even a single condition depending on the L. monocytogenes subgroup of interest.
Transmission and Establishment of a Persistent Infection ofEnterocytozoon bieneusi, Derived from a Human with AIDS, in Simian Immunodeficiency Virus—Infected Rhesus Monkeys (1997)

Enterocytozoon bieneusi is closely linked with chronic diarrhea and wasting in AIDS. Although reported >10 years ago, little is known about the infection and the disease it induces in humans. Duodenal E. bieneusi spores from an AIDS patient were orally transmitted to 2 simian immunodeficiency virus-infected rhesus monkeys. Both animals began shedding spores within a week of inoculation, as confirmed by microscopy and polymerase chain reaction, and continued until euthanatized 7 and 8 months later. E. bieneusi infection in the gut was sparse, either because of moderate numbers of circulating CD4 cells or because monkeys are less susceptible than humans to this infection. This is apparently the first documented transmission of E. bieneusi infection between hosts.
Kaposi's Sarcoma-Associated Herpesvirus LANA2 Is a B-Cell-Specific Latent Viral Protein That Inhibits p53 (2001)

Kaposi's sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8, is associated with three proliferative diseases ranging from viral cytokine-induced hyperplasia to monoclonal neoplasia: multicentric Castleman's disease (CD), Kaposi's sarcoma (KS), and primary effusion lymphoma (PEL). Here we report a new latency-associated 1,704-bp KSHV spliced gene belonging to a cluster of KSHV sequences having homology to the interferon regulatory factor (IRF) family of transcription factors. ORFK10.5 encodes a protein, latency-associated nuclear antigen 2 (LANA2), which is expressed in KSHV-infected hematopoietic tissues, including PEL and CD but not KS lesions. LANA2 is abundantly expressed in the nuclei of cultured KSHV-infected B cells. Transcription of K10.5 in PEL cell cultures is not inhibited by DNA polymerase inhibitors nor significantly induced by phorbol ester treatment. Unlike LANA1, LANA2 does not elicit a serologic response from patients with KS, PEL, or CD as measured by Western blot hybridization. Both KSHV vIRF1 (ORFK9) and LANA2 (ORFK10.5) appear to have arisen through gene duplication of a captured cellular IRF gene. LANA2 is a potent inhibitor of p53-induced transcription in reporter assays. LANA2 antagonizes apoptosis due to p53 overexpression in p53-null SAOS-2 cells and apoptosis due to doxorubicin treatment of wild-type p53 U2OS cells. While LANA2 specifically interacts with amino acids 290 to 393 of p53 in glutathione S-transferase pull-down assays, we were unable to demonstrate LANA2-p53 interaction in vivo by immunoprecipitation. These findings show that KSHV has tissue-specific latent gene expression programs and identify a new latent protein which may contribute to KSHV tumorigenesis in hematopoietic tissues via p53 inhibition.
Pemetaan Usaha Budidaya Perikanan Air Tawar Di Wilayah Kabupaten Dati II Malang (1999)

Wilayah Kabupaten Malang merupakan suatu kawasan yang permintaan akan produk-produk perikanannya cukup besar. Perkembangan konsumsi ikan perkapita masyarakat Kabupaten Malang pada tahun 1997 dan I998 adalah 14,02 dan 14,23 kg/perkapita/tahun, sedangkan target nasional 22,5 kg/perkapita/tahun. Untuk pemenuhan kebutuhan tersebut masyarakat Kabupaten Malang mengusahakan dengan berbagai cara disamping produksi ikan dari kawasan sendiri juga mendatangkan dari Iuar daerah . Kawasan ini memiliki potensi sumber daya alam yang potensial khususnya kawasan subur dan perairan umum yang bisa dimanfaatkan untuk tujuan pemenuhan protein hewani masyarakat. Tujuan Penelitian ini adalah (1) memetakan usaha budidaya perikanan air tawar di wilayah Kabupaten Malang (2) menentukan daerah-daerah yang sangat mendukung untuk usaha budidaya air tawar (3) sebagai upaya identiﬁkasi potensi dan komoditas budidaya air tawar di Kabupaten Malang. Penelitian ini dilakukan dengan metode survey di 35 kecamatan di Kabupaten Malang. Teknik pengambilan data dengan pengumpulan data primer dam sekunder. Data primer dianalisa melalui pendekatan produksi dengan nilai LQ, pendekatan agroekosistem, agrobisnis dan pendekatan kebijakan dengan pemberian nilai skor. Dari analisa tersebut didapatkan daerah-daerah yang sangat mendukung untuk usaha - usaha budidaya air tawar. Dari hasil penelitian yang diiakukan dapat dikemukakan hal-hal sebagai Berikut: 
I. Daerah-daerah yang sangat mendukung untuk usaha budidaya a. Kolam meliputi : Kecamatan Batu, Singosari, Lawang, Wajak dan Turen b. Mina padi meliputi : Kecamatan Ngajum dan Turen. c. Karamba meliputi : Kecamatan Batu, Junrejo, Singosari, Lawang, Pakis, Wajak, Turen, Kepanjen, Ngajum d. Jaring apung meliputi : Kecamatan kalipare, sumberpucung dan Pagak 
2. Sistem budidaya (teknologi ) yang berkembang di wilayah Kecamatan-kecamatan Kabupaten Malang antara Iain ; Kolam ( I00 % ), mina padi ( 37,14 % ), Karamba ( 28,85 % ) dan Jaring apung ( 8,57 % ). 
3. Sedangkan komoditas ikan yang telah dibudidayakan wilayah Malang antara lain meliputi , ikan Lele ( 94,28 %), Tombro (57,l4 %), Nila ( 37,14 %), Gurami ( 20,0% ), Katak ( 25,7l%) dan Ikan Hias dan lain-Iain( 11,42 %).