gebhart/patrepeval huggingface dataset:
Potential Gains of Reactive Video QoE Enhancement by App Agnostic QoE Deduction (2016)

We propose an app agnostic QoE deduction method that can be used for on-line traffic prioritization. Our implemented method extracts QoE information directly from the screen of mobile devices and this information is utilized for video traffic prioritization to improve user QoE. We evaluate our method and show that it can realize 80-100% of the achievable gain of the state-of-the-art methods with 50% less traffic that needs to be prioritized to achieve this. We provide deployment alternatives for traffic prioritization and evaluate performance impact on achievable gain.
Qualitative Model Based Diagnosis of Abrupt Faults (2000)

The familial nature of OCD has been well established. Clinical characteristics such as early age of onset, comorbidity with tic disorders, and higher rates of symmetry symptoms have been associated with the familial aggregation of OCD, though little research has examined the differential impact of paternal and maternal OCD. The current study explored parental influence on the expression of these characteristics and reports on 310 probands diagnosed with OCD as well as 1,580 of their biological first-degree relatives. The probands were evaluated by trained clinical raters using semi-structured assessments, and relative diagnoses were obtained based on probands' reports. Similar to previous findings, 10.13% of the 1,580 relatives (<i>n</i> = 160) were reported to have significant OCD symptoms. Only probands who reported having a father with OCD, rather than any first-degree relative, were more likely to have an early age of onset, symmetry and exactness obsessions, and higher rates of comorbidity. No significant differences were found with respect to the probands who reported their mothers as having OCD. These findings suggest that paternal OCD, rather than simply any first-degree relative having OCD, may influence whether probands exhibit the clinical characteristics commonly associated with the familial subtype of OCD.
Design for Manufacturability and its Role in Enhancing Stress Migration Reliability of Porous Ultra Low-k Copper Interconnects (2007)

The integration of copper (Cu) and low-k dielectrics has posed challenges for stress migration (SM) reliability. Besides process tuning, design for manufacturability (DFM) approach is proposed to suppress stress-induced void failures. In this paper, a three-dimensional (3D) finite element analysis (FEA) simulation model was used to identify the main mechanisms of several key processes and design approaches responsible for SM reliability improvement reported in the literature. On the basis of understanding the critical parameters and design/structural weak points affecting SM reliability, DFM is proposed to enhance the SM reliability of future nanoscale technologies employing porous ultra low-k dielectrics. The study illustrates the importance of process and design interactions to make porous ultra low-k Cu interconnects more resilient to SM degradation for future CMOS technologies.
Design of a multi-cell power amplifier for WCDMA application (2006)

This paper presents several techniques in order to improve the trade-off linearity/efficiency in power amplifiers for WCDMA application. First of all, the study of a differential bipolar linearizer is addressed; second, the consumption control via switched biases and power cells. Simulations were carried out with a BiCMOS process and they show a 27 dBm linear power amplifier (PA) output power with a power added efficiency up to 35% and a 31 dBm maximum output power with a 45% power added efficiency (PAE).
Crosscorrelation time-pick workflow of microseismic data starting from migration-based locations (2020)

Using migration-based methods, we developed a workflow to obtain high-quality time picks for microseismic event data. The workflow crosscorrelates manually picked waveforms of template microseismic events with waveforms from the remaining events to refine the first arrival time picks of P and S phases. We applied our workflow to 50 minutes of microseismic data from a hydraulic fracturing monitoring campaign. The workflow provides high-quality picks for 689 out of a total of 805 detected events by using three representative template events. We validate the time picks by comparing event locations using the crosscorrelation picks with locations from the migration based method. The workflow improves time-pick accuracy, which subsequently may be used to improve associated source parameters and other attributes that require a precise time-pick of the signal onset. Presentation Date: Wednesday, October 14, 2020 Session Start Time: 9:20 AM Presentation Time: 9:45 AM Location: Poster Station 11 Presentation Type: Poster
ChemInform Abstract: SOLAR ENERGY STORAGE REACTIONS. DETERMINATION OF THE STRUCTURE OF THE COMPLEX FORMED BY VISIBLE IRRADIATION OF RH2(BRIDGE)42+ IN AQUEOUS HYDROCHLORIC ACID SOLUTIONS (1980)

Abstract Röntgenstrukturanalyse des Komplexes (I).
Synthesis and resolution of the planar chirality of ester-functionalised phospharuthenocenes (2004)

Menthyl phospholide ester anions provide an operationally simple and high yielding entry to the first planar chiral enantiopure phospharuthenocene derivatives.
Frequency switching in a relativistic magnetron with diffraction output (2011)

The possibility of mode switching from one pulse to the next in a 6-cavity gigawatt magnetron with diffraction output (MDO) using a weak (200-300 kW), short (about 10 ns), single frequency RF signal has been demonstrated using particle-in-cell (PIC) computer simulations [1]. This mode switching is possible because of the symmetric nature of the MDO that facilitates the use of any eigenmode as the operating mode. All scenarios of mode switching were considered using common properties of dynamical systems with two stable states separated by an unstable saddle point. In this paper we continue to study the problem of mode switching for a 12-cavity MDO for which we found a splitting of the radiated frequency for each eigenmode owing to its different longitudinal distribution. Since the splitting is realized as a bifurcation from a higher frequency to a lower one as the applied magnetic field is increased, scenarios of frequency switching are considered as in [1] for the TE <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">41</sub> -mode whose radiated power is maximal for the MDO under consideration.
Robust elastic 2D/3D geometric graph matching (2012)

We present an algorithm for geometric matching of graphs embedded in 2D or 3D space. It is applicable for registering any graph-like structures appearing in biomedical images, such as blood vessels, pulmonary bronchi, nerve fibers, or dendritic arbors. Our approach does not rely on the similarity of local appearance features, so it is suitable for multimodal registration with a large difference in appearance. Unlike earlier methods, the algorithm uses edge shape, does not require an initial pose estimate, can handle partial matches, and can cope with nonlinear deformations and topological differences. The matching consists of two steps. First, we find an affine transform that roughly aligns the graphs by exploring the set of all consistent correspondences between the nodes. This can be done at an acceptably low computational expense by using parameter uncertainties for pruning, backtracking as needed. Parameter uncertainties are updated in a Kalman-like scheme with each match. In the second step we allow for a nonlinear part of the deformation, modeled as a Gaussian Process. Short sequences of edges are grouped into superedges, which are then matched between graphs. This allows for topological differences. A maximum consistent set of superedge matches is found using a dedicated branch-and-bound solver, which is over 100 times faster than a standard linear programming approach. Geometrical and topological consistency of candidate matches is determined in a fast hierarchical manner. We demonstrate the effectiveness of our technique at registering angiography and retinal fundus images, as well as neural image stacks.
The effects of strain history on aortic valve interstitial cell activation in a 3D hydrogel environment (2023)

Aortic valves (AVs) undergo unique stretch histories that include high rates and magnitudes. While major differences in deformation patterns have been observed between normal and congenitally defective bicuspid aortic valves (BAVs), the relation to underlying mechanisms of rapid disease onset in BAV patients remains unknown. To evaluate how the variations in stretch history affect AV interstitial cell (AVIC) activation, high-throughput methods were developed to impart varied cyclical biaxial stretch histories into 3D poly(ethylene) glycol hydrogels seeded with AVICs for 48 h. Specifically, a physiologically mimicking stretch history was compared to two stretch histories with varied peak stretch and stretch rate. Post-conditioned AVICs were imaged for nuclear shape, alpha smooth muscle actin (αSMA) and vimentin (VMN) polymerization, and small mothers against decapentaplegic homologs 2 and 3 (SMAD 2/3) nuclear activity. The results indicated that bulk gel deformations were accurately transduced to the AVICs. Lower peak stretches lead to increased αSMA polymerization. In contrast, VMN polymerization was a function of stretch rate, with SMAD 2/3 nuclear localization and nuclear shape also trending toward stretch rate dependency. Lower than physiological levels of stretch rate led to higher SMAD 2/3 activity, higher VMN polymerization around the nucleus, and lower nuclear elongation. αSMA polymerization did not correlate with VMN polymerization, SMAD 2/3 activity, nor nuclear shape. These results suggest that a negative feedback loop may form between SMAD 2/3, VMN, and nuclear shape to maintain AVIC homeostatic nuclear deformations, which is dependent on stretch rate. These novel results suggest that AVIC mechanobiological responses are sensitive to stretch history and provide insight into the mechanisms of AV disease.
Comparison of magnetically navigated and conventional wire percutaneous coronary intervention of a single discrete stenosis (2009)

Abstract Objective : The objective of this study is to compare magnetic guidewire navigation in percutaneous coronary intervention (MPCI) to conventional percutaneous coronary intervention (CPCI) for the elective treatment of a single discrete stenosis. Background : Magnetic navigation actively steers an angioplasty wire‐tip and may improve PCI procedures, but it is not known whether the intricacy and increased preparation necessary for using the system negatively influences the performance of simple procedures in terms of time and contrast use. Methods : The procedures of 44 patients (mean age 65 ± 10 year) undergoing elective single vessel MPCI of a single discrete stenosis were matched for age, gender, and lesion location with 44 concurrent patients (mean age 65 ± 10 year) undergoing CPCI. The major endpoint was procedural time. Results : Technical success was defined as an intraluminal wire position distal to the stenosis. Procedural outcome, contrast use, and costs were evaluated. Clinical demographics and angiographic characteristics of the two groups were similar, except for a higher incidence of previous MI and class III angina pectoris in the conventional group. The technical success rate was high and identical in both groups (97.7%). Procedural and fluoroscopy times were not significantly different for MPCI compared to CPCI (21.0 ± 14.5 min vs. 24.7 ± 14.0 min; 4.9 ± 4.8 min vs. 7.3 ± 10.3 min, P = NS). There was a significant reduction in median contrast use [60 ml/patient (41–100) vs. 100 ml/patient (64–130); P = 0.006]. Conclusion : Magnetic navigation does not increase procedural time, irradiation, equipment use, or cost compared to conventional PCI of a single discrete stenosis. It proved feasible, yielding high rates of procedural success with less contrast use. © 2009 Wiley‐Liss, Inc.
Stable transverse mode emission in vertical-cavitysurface-emittinglasers antiguided by amorphous GaAs layer (1996)

The authors report the successful development of a method stabilising the fundamental transverse mode of a vertical-cavity surface-emitting laser using a low-temperature-deposited amorphous GaAs (a-GaAs) layer of a high refractive index. For a device of 10 µm diameter, stable fundamental mode emission has been observed over a wide range of current. Results are attributed to the antiguide effect of the a-GaAs-buried structure.
QoS support on fourth generation networks (2006)

The arrival of fourth generation mobile networks, based on IP core networks, lead us to the development of certain services, such as: Quality of service, mobility and AAA. This paper proposes architecture to supply quality of service support based in the differentiated services technique, known as Diffserv. In the same way we analyze the main components of this architecture: QoS Broker (central policy broker of quality of service, whose goal is the appropriate configuration of the routers in the network), Access Router (in charge of the management of the queuing system in order to provide QoS) and the AAA server (management of QoS user profiles).
Data from Results from an Integrated Safety Analysis of Urelumab, an Agonist Anti-CD137 Monoclonal Antibody (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Urelumab is an agonist antibody to CD137 with potential application as an immuno-oncology therapeutic. Data were analyzed to assess safety, tolerability, and pharmacodynamic activity of urelumab, including the dose selected for ongoing development in patients with advanced solid tumors and lymphoma.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; A total of 346 patients with advanced cancers who had progressed after standard treatment received at least one dose of urelumab in one of three dose–escalation, monotherapy studies. Urelumab was administered at doses ranging from 0.1 to 15 mg/kg. Safety analyses included treatment-related and serious adverse events (AEs), as well as treatment-related AEs leading to discontinuation and death, with a focus on liver function test abnormalities and hepatic AEs.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; Urelumab doses between 1 and 15 mg/kg given every 3 weeks resulted in a higher frequency of treatment-related AEs than 0.1 or 0.3 mg/kg every 3 weeks. Dose was the single most important factor contributing to transaminitis development, which was more frequent and severe at doses ≥1 mg/kg. At the MTD of 0.1 mg/kg every 3 weeks, urelumab was relatively well tolerated, with fatigue (16%) and nausea (13%) being the most common treatment-related AEs, and was associated with immunologic and pharmacodynamic activity demonstrated by the induction of IFN-inducible genes and cytokines.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Integrated evaluation of urelumab safety data showed significant transaminitis was strongly associated with doses of ≥1 mg/kg. However, urelumab 0.1 mg/kg every 3 weeks was demonstrated to be safe, with pharmacodynamic activity supporting continued clinical evaluation of this dose as monotherapy and in combination with other immuno-oncology agents. &lt;i&gt;Clin Cancer Res; 23(8); 1929–36. ©2016 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
The Effect of an Aerobic Exercise Training Program on Quality of Life in Type 2 Diabetes (2003)

No physiological changes were significantly associated with scores on the SF36v2 health survey. In addition, neither training nor the presence of type 2 diabetes significantly affected the physical or mental component scores on the QOL survey.
Synthesis of Retinals Fluorinated at Odd-Numbered Side-Chain Positions and of the Corresponding Fluorobacteriorhodopsins (1997)

Conventional Horner-Wadsworth-Emmons and Wittig condensations were used to fluorinate the odd-numbered positions of the retinal side chain past C(7). The stereochemically labile cis-fluororetinals were easily converted into the most stable trans-fluororetinals, which were incubated with bacterio-opsin. Contrary to expectations, the fluorinated retinals provided artificial pigments with near normal absorption properties, showing that any electrostatic interactions between the fluorine atoms and protein groups were insufficient to prevent normal binding. The new artificial pigments had smaller opsin shifts than did native bacteriorhodopsin, which is interpreted as due either to greater electrostatic interaction between the protonated imine and its counterion, or to local interactions between the fluorine substituents and nearby polar protein groups.
Esophagitis dissecans superficialis : a case series of 7 patients and review of the literature. (2018)

EDS is a rare benign entity that endoscopists must be aware of in order not to mistake it for other entities such as esophagitis or squamous cell carcinoma. The diagnosis is based on biopsies. The prognosis is good after stopping the causative agent.
Influence of Impactor Operating Flow Rate on Particle Size Distribution of Four Jet Nebulizers (2007)

When a nebulizer is evaluated by the Andersen Cascade Impactor (ACI), the flow rate is generally maintained at 28.3 L/min, as recommended by the manufacturer. However, the nebulizer flow rate that a patient inhales is only around 18 L/min. Because the drive flow of a nebulizer is approximately 6-8 L/min, the nebulized drug is mixed with outside air when delivered. Evaluating impactor performance at the 28.3 L/min flow rate is less than ideal because an additional 10 L/min of outside air is mixed with the drug, thereby affecting the drug size distribution and dose before inhalation and deposition in the human lung. In this study we operated the ACI at an 18.0 L/min flow rate to test whether the effect of the changing ambient humidity was being exaggerated by the 28.3 L/min flow rate. The study was carried out at three different relative humidity levels and two different impactor flow rates with four commercially available nebulizers. The mass median aerodynamic diameter (MMAD) and the geometric standard deviation (GSD) of the droplets were found to increase when the impactor was operated at a flow rate of 18 L/min compared to that of 28.3 L/min. The higher MMAD and GSD could cause the patient to inhale less of the drug than expected if the nebulizer was evaluated by the ACI at the operating flow rate of 28.3 L/min.
Yield improvement for lost mould rapid infiltration forming process by a multistage fractional factorial split plot design (2009)

Statistical design of experiments is widely used among scientists and engineers to understand influential factors in a laboratory or manufacturing process. One of the underlying principles of using the statistical design of experiments method is randomisation, each run of experimental settings will be determined completely unsystematically. In practice, especially in a complicated process that consists of multiple stages, randomisation may pose too high a burden on time and cost.In this study, the multistage fraction factorial split plot design is proposed for green yield improvement in a lost mould rapid infiltration process that has been developed to fabricate zirconia ceramic parts. This design allows a relaxation of the randomisation principle so that certain experimental runs can be carried out in convenient groups. The results indicate that the type of immersion chemical and mould coating play a role in improving process yield. Additionally, the results suggest that a mould infiltration machine should be used to improve the reproducibility of the process.
In situ synthesis of polycrystalline cubic boron nitride with high mechanical properties using rod-shaped TiB2 crystals as the binder (2017)

Polycrystalline cubic boron nitride (PcBN) was sintered in the temperature range of 1050–1650°C under an ultra-high pressure of 5.0 GPa for 20 min using an in situ synthesis method. X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy and energy-dispersive spectrometry were used to study the compositional and morphological changes during the synthetic process. The results showed that rod-shaped TiB2 crystals could be detected at 1150°C, and their quantity increased with sintering temperatures. The TiB2 crystals distributed homogeneously and grew randomly among the cBN grain boundaries and interstitial spaces, ultimately forming an interlocking structure. The PcBN prepared at 1650°C exhibited optimal comprehensive mechanical properties, with a micro-hardness of 44.42 GPa and a flexural strength of 862.5 MPa. Moreover, based on the experimental results, the chemical reaction mechanism and the strengthening mechanisms occurred during the sintering process were also proposed to properly interpret the synthesis of PcBN.
Coding across unicast sessions can increase the secure message capacity (2016)

This paper characterizes the secret message capacity of three networks where two unicast sessions share some of the communication resources. Each network consists of erasure channels with state feedback. A passive eavesdropper is assumed to wiretap any one of the links. The capacity achieving schemes as well as the outer bounds are formulated as linear programs. The proposed strategies are then numerically evaluated and shown to achieve higher rate performances (up to a double single- or sum-rate) with respect to alternative strategies, where the network resources are time-shared among the two sessions. These results represent a step towards the secure capacity characterization for general networks. They also show that, even in configurations for which network coding does not offer benefits in absence of security, it can become beneficial under security constraints.
Properties of primary motor cortical local field potentials in the leg and trunk representations during arm movements (2016)

Large, spatially-distributed populations of motor cortical neurons are recruited during upper limb movements. Here, we examined how beta attenuation, a mesoscopic reflection of unit engagement, varies across a spatially expansive sampling of primary motor cortex in a non-human primate (macaca mulatta). We found that electrodes in both the trunk and leg representation of motor cortex exhibit qualitatively similar behavior to electrodes in the arm representation during a planar reaching task, despite the fact that there were no overt movements of the trunk or leg. These findings are interpreted in the context of a state-based brain machine interface.
Opto-electronic modeling of light emission from avalanche-mode silicon p+n junctions (2015)

This work presents the modeling of light emission from silicon based p+n junctions operating in avalanche breakdown. We revisit the photon emission process under the influence of relatively high electric fields in a reverse biased junction (&amp;gt;105 V/cm). The photon emission rate is described as a function of the electron temperature Te, which is computed from the spatial distribution of the electric field. The light emission spectra lie around the visible spectral range (λ∼ 300–850 nm), where the peak wavelength and the optical intensity are both doping level dependent. It is theoretically derived that a specific minimum geometrical width (∼170 nm) of the active region of avalanche is required, corresponding to a breakdown voltage of ∼5 V, below which the rate of photon emission in the desired spectrum drops. The derived model is validated using experimental data obtained from ultra-shallow p+n junctions with low absorption through a nm-thin p+ region and surface coverage of solely 3 nm of pure boron. We observe a peak in the emission spectra near 580 nm and 650 nm for diodes with breakdown voltages 7 V and 14 V, respectively, consistent with our model.