gebhart/patrepeval huggingface dataset:
Experimental estimation of Molecular structure of the Water-Rock interface inferred from in situ IR-Raman Spectroscopy up to 40 °C, 50 MPa (2008)

In order to investigate the molecular effects of interfacial water on rock surface by infrared (IR) and Raman spectroscopy, high temperature‐pressure cell (up to 400 °C and 50 MPa) worked with optical microscopy was developed. This apparatus can measure IR and Raman spectra of water on a metal and quartz surface at high temperature and pressure (HT & HP) conditions in situ. As a result of IR spectroscopic measurements of water on a metal, the broad peak at ca. 3400 cm−1, attributed to OH stretching vibration of water molecules was observed at high temperature and pressure conditions. Continuous shift of the OH vibration mode was obtained from room condition to hydrothermal condition. Compared with the result of IR properties of water on a metal, IR properties of water on quartz surface exhibit different trend: the peak position shifted to higher wavenumber with increasing temperature and slightly shifted with pressure. In addition, IR spectra of water in mesoporous silica were measured. IR property of water in mesoporous silica was changed depending on pore diameter. Mesoporous silica having smaller diameter restrict the vibration of water molecules. IR property of water was changed by environmental conditions such as temperature, pressure and substrate. Molecular structure of interfacial water on solid material at elevated temperatures and pressures were not only changes due to physical conditions such as temperature and pressure but also interaction between water and solid surface.
Контроль негативного влияния воды на активность и стабильность пропиточного Cо-катализатора синтеза Фишера–Тропша (2017)

Показана возможность контроля негативного действия воды на активность и стабильность пропиточного Со катализатора синтеза ФТ и теплопроводящую добавку, входящую в его состав, путем введения в состав катализатора цеолита для создания гидрофобной поверхности. Введение цеолитов в Н-форме в Со-катализатор позволяет контролировать гидрофобность его поверхности, что способствует повышению производительности процесса и предотвращает окисление теплопроводящего компонента. При этом увеличиваются стабильность работы и срок службы катализатора.
Capacitance Transient Spectroscopy (1977)

This article reviews published data on the mechanical properties of additively manufactured metallic materials. The additive manufacturing techniques utilized to generate samples covered in this review include powder bed fusion (e.g., EBM, SLM, DMLS) and ...Read More
Adaptive bandwidth reservation mechanism using mobility probability in mobile multimedia computing environment (2002)

In this paper, ARMM (adaptive-bandwidth reservation mechanism using MPP) is proposed to provide the consistent QoS guarantees for multimedia traffic in a mobile computing environment. Each cell can reserve fractional bandwidths for hand-off calls to its adjacent cells, and this aggregated reservation of bandwidth can only be used for hand-off calls and not for new calls. It is important to determine the right amount of reserved bandwidth for hand-off calls, because the blocking probability of new calls would increase if we reserve more bandwidth than being necessary. This paper proposes an algorithm based on a MPP (mobility pattern profile) and a 2-tier cell structure to determine the amount of bandwidth to be reserved in the cell and to dynamically control its amount based on its network condition.
Computer Simulation of Radiotherapy for Malignant Tumor - A Mechanical Analogy Method - (2009)

A new simulation method was developed that considered a tumor as a solid body and therapeutic response as deformation of the tumor using mechanical analogy. As radiation exposure to the tumor was related to the external force to the solid body, the geometrical change of the tumor could be estimated from fundamental equations in solid mechanics. A change in tumor volume was calculated using finite element (FE) method. The FE models were constructed from CT images of patients before the radiotherapy. The initial radiotherapeutic parameters of tumor radioresistance and repopulation rate were determined based on a linear-quadratic model and then revised by the comparison with actual tumor volume change. Three patients with uterine cervix carcinoma were applied in this method. Simulation results well showed tendencies of tumor volume changes with radiotherapy. In addition, this method could provide the appropriate value of radiotherapeutic parameters for individual case. In conclusion, our approach could calculate three-dimensional tumor deformation during the course of radiotherapy and will provide useful information for more effective treatment.
Position estimation of lap joints for seam tracking applications at mm-wave frequencies (2013)

In this paper, we present the results of using a frequency-stepped continuous-wave radar system to estimate the position of overlapping and electrically good conductive plates. We especially focus on polarimetric scattering effects caused by the step of a lap joint, which is a common welding-geometry. To model the step's contribution to the overall scattered signal, we use a two-dimensional combined field integral equation (CFIE) approach. For demonstrating its practical applicability, the implemented scattering model is verified by measurements. To emphasize the improvements of position estimation by using a CFIE approach, the outcomes of the model are compared to a commonly used point scattering model. Finally, the numerical signal is utilized to precisely estimate the position of the lap joint.
Pyridone Derivatives as Potent and Selective VLA‐4 Integrin Antagonists. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Bubble‐free oxygenation of a bi‐enzymatic system: effect on biocatalyst stability (2008)

The effect of bubble-free oxygenation on the stability of a bi-enzymatic system with redox mediator regeneration for the conversion of lactose to lactobionic acid was investigated in a miniaturized reactor with bubbleless oxygenation. Earlier investigations of this biocatalytic oxidation have shown that the dispersive addition of oxygen can cause significant enzyme inactivation. In the process studied, the enzyme cellobiose dehydrogenase (CDH) oxidizes lactose at the C-1 position of the reducing sugar moiety to lactobionolactone, which spontaneously hydrolyzes to lactobionic acid. 2,2'-Azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) diammonium salt was used as electron acceptor for CDH and was continuously regenerated (reoxidized) by laccase, a blue multi-copper oxidase. Oxygen served as the terminal electron acceptor of the reaction and was fully reduced to water by laccase. The overall mass transfer coefficient of the miniaturized reactor was determined at 30 and 45 degrees C; conversions were conducted both in the reaction-limited and diffusion-limited regime to study catalyst inactivation. The bubbleless oxygenation was successful in avoiding gas/liquid interface inactivation. It was also shown that the oxidized redox mediator plays a key role in the inactivation mechanism of the biocatalysts unobserved during previous studies.
[Peptide bioregulators: the new class of geroprotectors. Communication 1. Results of experimental studies]. (2012)

This review summarizes the results of long-term researches of the authors who studied the mechanisms of aging and the effectiveness of peptide bioregulators in preventing age-related diseases in laboratory animals. The data is provided on the evaluation of peptides effects which were produced using the most modern techniques in scientific institutions in Russia and abroad. The main attention is paid to the ability of peptide bioregulators to increase the life span and inhibit the carcinogenesis in animals.
Secure Decoupled Linkage (SDLink) system for building a social genome (2013)

Population informatics is the systematic study of populations via secondary analysis of massive data collections about people, called the social genome. A major challenge in building the social genome is the difficulty in data integration of heterogeneous and uncoordinated data while protecting the confidentiality of the data subjects. Here, we present our work in designing a flexible computerized third party linkage platform, Secure Decoupled Linkage (SDLink), which can provide both privacy protection and accurate high quality integrated data using a hybrid human-machine data integration system. Our evaluation results show that chaffing used in combination with universe manipulation is very effective in blocking inferences during the clerical review process.
Rapid and extraction-free detection of SARS-CoV-2 from saliva with colorimetric LAMP (2020)

Rapid, reliable, and widespread testing is required to curtail the ongoing COVID-19 pandemic. Current gold standard nucleic acid tests are hampered by supply shortages in critical reagents including nasal swabs, RNA extraction kits, personal protective equipment (PPE), instrumentation, and labor. Here we present an approach to overcome these challenges with the development of a rapid colorimetric assay using reverse-transcription loop-mediated isothermal amplification (RT-LAMP) optimized on human saliva samples without an RNA purification step. We describe our optimizations of the LAMP reaction and saliva pretreatment protocols that enabled rapid and sensitive detection of < 102 viral genomes per reaction in contrived saliva controls. Moreover, our saliva pretreatment protocol enabled sensitive viral detection by conventional quantitative reverse transcription polymerase chain reaction (qRT-PCR) without RNA extraction. We validated the high performance of these assays on clinical samples and demonstrate a promising approach to overcome the current bottlenecks limiting widespread testing.
Interactions entre les sites de transport et le site catalytique de l'atpase-ca du reticulum sarcoplasmique revelees par la liaison du calcium et des protons (1994)

L'atpase-ca du reticulum sarcoplasmique est une proteine membranaire etudiee comme modele de transport actif d'ions. Elle couple le transport de calcium contre son gradient de concentration a l'hydrolyse d'atp. Le travail presente dans cette these a essentiellement porte sur la liaison de calcium aux sites de transport du cote cytoplasmique. L'etude de la liaison de calcium a l'equilibre a permis de proposer un schema decrivant l'interaction entre le calcium, les protons et le magnesium qui sont les principaux effecteurs du transport avec l'atp. D'apres ce schema, les deux ions calcium sont echanges pour trois protons en accord avec l'hypothese d'un contretransport calcium/proton ; le premier ion calcium est en competition avec deux protons et le second est en competition avec un troisieme proton. Le calcium interagit egalement avec deux ions magnesium, mais contrairement au cas des protons les liaisons de calcium et de magnesium ne sont pas exclusives. Ce schema a ete verifie a l'aide d'autres experiences. L'etude, notamment, de l'effet du ph sur la cinetique de liaison du calcium a montre que les dissociations de protons sont les etapes limitantes de la liaison du calcium. La sensibilite au ph de la phosphorylatrion par pi en absence de calcium suggere que les protons de notre schema sont ceux contretransportes. La mise en evidence d'une competition de trois protons contre deux ions calcium du cote luminal confirme cette hypothese. Notre schema nous a ensuite permis de comprendre par quel mecanisme l'atp accelere la liaison du calcium. Le principal effet de l'atp est d'inhiber la liaison des protons, la liaison de calcium sur les especes deprotonees etant plus rapide la liaison du calcium est acceleree. Enfin, ces resultats nous ont permis de proposer un mecanisme pour la communication entre les sites de transport et le site catalytique
Dirac cone protected by non-symmorphic symmetry and three-dimensional Dirac line node in ZrSiS (2016)

Materials harbouring exotic quasiparticles, such as massless Dirac and Weyl fermions, have garnered much attention from physics and material science communities due to their exceptional physical properties such as ultra-high mobility and extremely large magnetoresistances. Here, we show that the highly stable, non-toxic and earth-abundant material, ZrSiS, has an electronic band structure that hosts several Dirac cones that form a Fermi surface with a diamond-shaped line of Dirac nodes. We also show that the square Si lattice in ZrSiS is an excellent template for realizing new types of two-dimensional Dirac cones recently predicted by Young and Kane. Finally, we find that the energy range of the linearly dispersed bands is as high as 2 eV above and below the Fermi level; much larger than of other known Dirac materials. This makes ZrSiS a very promising candidate to study Dirac electrons, as well as the properties of lines of Dirac nodes.
Optical cross-connect with adaptive intra-node contention (2013)

Within the context of colorless and multidirectional wavelength routing node, this study illustrates the trade-off in terms of connectivity, total add/drop capacity, and intra-node contention.
Histomorphologic Changes of the Long Head of the Biceps Tendon in Common Shoulder Pathologies (2013)

The pathomechanisms of the various forms of known LHB diagnoses are not yet fully understood and basic science studies may help in understanding their etiology and therefore optimizing treatment options.
A simplified approach for autonomous quality assessment of cyclic movements (2013)

To monitor performance in athletic training it is of great importance to detect and extract significant movement features. We analyzed the utility of randomly modulated periodicity and sum signal-to-modulation-noise-ratio (SMNR) for the evaluation of the foot-rest force (FRF), which is a key parameter in rowing. The foot-rest force of elite and novice athletes was recorded with an indoor rower and processed off-line. The results showed that there were significant differences between the sum SMNRs of FRF recordings obtained from elite and novice athletes. Moreover the randomly modulated periodicity feature of FRF facilitates spotting the training course as well as the efficiency of the training method especially in autonomous activity detection and rehabilitation devices. The sum SMNR feature can be used not only to distinguish expert athletes from novice athletes but also to deliver a reliable measure of performance to track improvements during the training and/or after rehabilitation.
Intelligent Diabetes Assistant: Using machine learning to help manage diabetes (2008)

We believe that machine learning can be used to help diabetics and care providers manage diabetes by predicting the effect that behaviors have on blood glucose. This when coupled with telemedicine could help care providers provide better individualized therapy more frequently. Currently, diabetics might get 15 minutes of interaction with a health expert during a checkup, and in that amount of time the physician must quickly evaluate the patient's health to offer therapy advice. The Intelligent Diabetes Assistant (IDA) addresses this problem by remotely collecting data, instantaneously sharing that data with a physician, and automatically processing the data to reveal important patterns. The system makes data collection more efficient for the patient, and it will make data analysis more efficient for the care team. We have conducted a two week longitudinal study tracking the lifestyle, nutrition, and blood glucose readings of 10 diabetics using IDA.
Bonding Mechanism and Microstructure of Bonded Zone of AlN Ceramics with Ti-AgCu Brazing Metal. (1991)

Metallization and bonding of AIN ceramics were made using active brazing metal (Ti-AgCu). Active brazing metal used in metallization and bonding was in paste form prepared by adding Ti powder and organic solvent in to eutectic silver brazing metal powder.Characterization and bonding mechanism of the bonded layer, and relation between the thichness of the reacted layer and bonding strength were studied.The results of this study are as follows :(1) The microstructure of the bonded layer between AIN ceramics and Ti-AgCu brazing metal is found to be TiN layer of about 0.2 to 0.8 μm in thickness at the AIN interface, a composite layer of TiC, AICu as a middle layer and Ag-Cu alloy layer at the surface side.(2) Thickness of TiN layer did not change by the amount of Ti addition in silver brazing metal but the thicness of TiCu and AlCu layers are increased with increase of Ti addition in silverbrazing metal. Activation energy of growth of TiN layer is found to be 20 kJ/mol.(3) When the amount of Ti addition is more than 15 mass%, the bonding strength is decresed and the bonded layer is broken. Because the thickness of brittle TiCu layer increases with the increase of the Ti cotent in silver brazing metal.
ChemInform Abstract: Chemical Inhibitors of Protein Kinases (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
B Cell IgD Deletion Prevents Alveolar Bone Loss Following Murine Oral Infection (2009)

Periodontal disease is one of the most common infectious diseases of humans. Immune responses to infection trigger loss of alveolar bone from the jaw and eventual tooth loss. We investigated the contribution of B cell IgD to alveolar bone loss by comparing the response of B cell normal BALB/cJ mice and IgD deficient BALB/c-Igh-5(-/-J) mice to oral infection with Porphyromonas gingivalis, a gram-negative periodontopathic bacterium from humans. P. gingivalis-infected normal mice lost bone. Specific antibody to P. gingivalis was lower and oral colonization was higher in IgD deficient mice; yet bone loss was completely absent. Infection increased the proportion of CD69(+) activated B cells and CD4(+) T cells in immune normal mice compared to IgD deficient mice. These data suggest that IgD is an important mediator of alveolar bone resorption, possibly through antigen-specific coactivation of B cells and CD4(+) T cells.
Supplementary Data from Pretreatment EGFR T790M Mutation and BRCA1 mRNA Expression in Erlotinib-Treated Advanced Non–Small-Cell Lung Cancer Patients with EGFR Mutations (2023)

&lt;p&gt;Supplementary Figures S1-S3; Supplementary Tables S1-S14.&lt;/p&gt;
Synthesis and photoluminescence properties of silicon nanowires treated by high‐pressure water vapor annealing (2007)

Abstract This paper reports on silicon nanowires (SiNWs) growth on porous silicon (PS) template using vapor‐liquid‐solid (VLS) technique and the effect of high‐pressure water vapor annealing (HWA) on their optical properties. Gold nanoparticles (Au NPs) with average mean diameter of 50 and 20 nm were used as catalysts. The SiNWs were obtained by thermal decomposition of silane gas (SiH 4 ) at high temperature (540 °C) catalyzed by the Au NPs. The resulting nanostructures display comparable diameter to the initial gold catalysts and are few microns long without a preferential growth direction. We have next examined the optical properties of the 20 nm diameter SiNWs. As‐prepared SiNWs display a weak photoluminescence (PL), which is related to the recombination emissions from defect centers. High‐pressure water vapor annealing (HWA) at 260 °C and 2.6 MPa of the SiNWs led to an increase of the PL by a factor 10 without significant changes in the emission band. TEM analysis of the HWA‐treated SiNWs showed a crystalline silicon core surrounded by an amorphous oxide layer. (© 2007 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)
A new approach for the electrothermal modeling of the power bipolar transistor (2002)

We have developed an electrothermal model for the bipolar power transistor, implemented in the Saber simulator, in which the device's temperature becomes an interactive variable during the simulation. Two approaches for the electrothermal coupling are compared and discussed. The accuracy of the model is appreciated with the electrical and thermal characterization of a NP/spl nu/N power bipolar transistor using the Iccap-Saber interface.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Upregulated functional gene expression programmes in tumour pericytes mark progression in patients with low‐grade glioma (2021)

Pericytes conceivably play important roles in the tumour microenvironment of glioblastoma multiforme (GBM) by allowing for an aberrant vasculature and acting as a component in the perivascular niche that supports glioma stem-like cells. However, a lack of specific markers has hampered in-depth elucidation of the functional contribution of pericytes to GBM. This study provides a comprehensive computational biology approach to annotate pericyte marker genes in the GBM vasculature through integration of data from single-cell RNA-sequencing studies of both mouse and human tissue, as well as bulk tumour and healthy tissue gene expression data from patients with GBM. We identified distinct vascular- and immune-related gene expression programmes in tumour pericytes that we assessed for association with GBM characteristics and patient survival. Most compellingly, pericyte gene signatures that were upregulated in tumours compared with normal brain tissue were indicative of progression of low-grade gliomas into high-grade glioma, suggested by a markedly shorter overall survival. Our results underline the functional importance of tumour pericytes in low-grade glioma and may serve as a starting point for efforts for precision targeting of pericytes.
AFCI Safeguards Enhancement Study: Technology Development Roadmap (2008)

The Advanced Fuel Cycle Initiative (AFCI) Safeguards Campaign aims to develop safeguards technologies and processes that will significantly reduce the risk of proliferation in the U.S. nuclear fuel cycle of tomorrow. The Safeguards Enhancement Study was chartered with identifying promising research and development (R&D) directions over timescales both near-term and long-term, and under safeguards oversight both domestic and international. This technology development roadmap documents recognized gaps and needs in the safeguarding of nuclear fuel cycles, and outlines corresponding performance targets for each of those needs. Drawing on the collective expertise of technologists and user-representatives, a list of over 30 technologies that have the potential to meet those needs was developed, along with brief summaries of each candidate technology. Each summary describes the potential impact of that technology, key research questions to be addressed, and prospective development milestones that could lead to a definitive viability or performance assessment. Important programmatic linkages between U.S. agencies and offices are also described, reflecting the emergence of several safeguards R&D programs in the U.S. and the reinvigoration of nuclear fuel cycles across the globe.
Magnetic properties of BiMnO3nanoparticles in SBA-15 mesoporous silica (2009)

Synthesis of novel magnetic iron metal-silica (Fe-SBA-15) and magnetite-silica(Fe3O4-SBA-15) nanocomposites with a high iron content using temperature-programedreduction