gebhart/patrepeval huggingface dataset:
Low Voltage High Speed Programming/Erasing Charge Trapping Memory with Metal-Al2O3-SiN-Si3N4-Si Structure (2007)

SONOS-type NAND flash memory cell with metal-Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> -SiN-Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> -Si was fabricated and key characteristics were investigated. Low voltage and high-speed programming/erasing characteristics were achieved, due to low barrier height of Si <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> and high dielectric constant of Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> compared with those of SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> . It also showed good endurance up to 10 k cycles, and more than 1.5 V memory windows after 10 years.
A robust and efficient method for the frequency domain analysis of non-uniform, lossy multi-line transmission structures (2002)

A new efficient and robust method of moment-based formulation for the analysis of non-uniform, lossy multi-line transmission structures is proposed. The stability and speed of this method are demonstrated by analyzing different non-uniform structures. The performances obtained show the proposed approach to be suitable for CAD applications.
Mass measurement accuracy of matrix‐assisted laser desorbed biomolecules: A Fourier‐transform ion cyclotron resonance mass spectrometry study (1994)

The use of binary matrices and internal calibrants to improve the mass measurement accuracy in matrix-assisted laser desorption ionization (MALDI) with Fourier-transform ion cyclotron resonance (FTICR) mass spectrometry is described. Binary matrices enhance the analyte ion yield and enable a complete MALDI-FTICR mass spectrum to be obtained from a single laser shot. The advantage of single-laser-shot data acquisition is that it eliminates line-broadening due to shot-to-shot frequency variations. It is shown that unresolved product ions, mainly due to loss of H2O and/or NH3, shift the centroid of an unresolved multi-component peak. A mass measurement accuracy of 12 ppm was obtained for the bovine insulin [M+H]+ ion using melittin as an internal calibrant.
Data from Altered Runx1 Subnuclear Targeting Enhances Myeloid Cell Proliferation and Blocks Differentiation by Activating a miR-24/MKP-7/MAPK Network (2023)

&lt;div&gt;Abstract&lt;p&gt;Disruption of Runx1/AML1 subnuclear localization, either by a single amino acid substitution or by a chromosomal translocation [e.g., t(8;21)], is linked to the etiology of acute myeloid leukemia (AML). Here, we show that this defect induces a select set of micro-RNAs (miR) in myeloid progenitor cells and AML patients with t(8;21). Both Runx1 and the t(8;21)-encoded AML1-ETO occupy the miR-24-23-27 locus and reciprocally control miR-24 transcription. miR-24 directly downregulates mitogen-activated protein kinase (MAPK) phosphatase-7 and enhances phosphorylation of both c-&lt;i&gt;jun&lt;/i&gt;-NH&lt;sub&gt;2&lt;/sub&gt;-kinase and p38 kinases. Expression of miR-24 stimulates myeloid cell growth, renders proliferation independent of interleukin-3, and blocks granulocytic differentiation. Thus, compromised Runx1 function induces a miR-dependent mechanism that, through MAPK signaling, enhances myeloid proliferation but blocks differentiation—key steps that contribute to leukemia. [Cancer Res 2009;69(21):8249–55]&lt;/p&gt;&lt;/div&gt;
An enhanced method for the estimation of end-to-end cell delay variation for real-time services (2003)

Delay accumulation is intended to be used in path calculations and for accumulating delay parameters in signaling protocols as a call progresses to provide estimates of the end-to-end values of these parameters. Delay parameters such as maximum cell transfer delay and peak-to-peak cell delay variation are important QoS parameters specified end-to-end for real-time services. It has been recognized that the existing delay accumulation method in the ATM Forum standards that is based on addition of quantile values of the delay density overestimates the actual delay and therefore causes underutilization of network resources. We describe the enhanced delay accumulation method which was proposed to the ATM Forum. The enhanced method performs better than the existing method, is simple to implement and requires fewer parameters than the other alternative, the asymptotic method. Furthermore, we demonstrate that the enhanced method is backward compatible with the existing method.
Ferrocene-derived P,N ligands: synthesis and application in enantioselective catalysis (2013)

Abstract Due to their unique steric and electronic properties, air-stability and modular structure, chiral hybrid P,N-ferrocenyl ligands play a prominent role in the field of asymmetric catalysis. This report aims to give a concise introduction to the syntheses of chiral hybrid P,N-ferrocenyl ligands and presents an overview of their application in enantioselective catalysis. This review is of special interest to chemists working on ligand design and asymmetric catalysis, as well as to the broader organic and inorganic community.
Nucleotide Substrate Specificity of Anti-Hepatitis C Virus Nucleoside Analogs for Human Mitochondrial RNA Polymerase (2017)

Nucleoside analog inhibitors (NAIs) are an important class of antiviral agents. Although highly effective, some NAIs with activity against hepatitis C virus (HCV) can cause toxicity, presumably due to off-target inhibition of host mitochondrial RNA polymerase (POLRMT). The <i>in vitro</i> nucleotide substrate specificity of POLRMT was studied in order to explore structure-activity relationships that can facilitate the identification of nontoxic NAIs. These findings have important implications for the development of all anti-RNA virus NAIs.
A computing origami (2009)

Stream processing represents an important class of applications that spans telecommunications, multimedia and the Internet. The implementation of streaming programs in FPGAs has attracted significant attention because of their inherent parallelism and high performance requirements. Languages, tools, and even custom hardware for streaming have been proposed, some of which are commercially available.
Detonation in Microchannel by the DSMC Method (2011)

A detonation wave propagation along a two-dimensional 1-mm-width channel in hydrogenoxygen stoichiometric mixture has been simulated by Direct Simulation Monte Carlo method. A detailed chemical kinetic mechanism for 6 species has been implemented and all the chemical reactions have been modeled at a level of molecular collisions. Unsupported Chapman-Jouguet detonation has been observed with condition of specular reflection of molecules on the side walls. When friction and heat conduction on the side walls are taken into account through diffuse reflection conditions a detonation wave is significantly weaker and its propagation velocity is lower than predicted by the Chapman-Jouguet theory.
Roles of chemokine receptor CX3CR1 in maintaining murine bone homeostasis through the regulation of both osteoblasts and osteoclasts (2013)

Summary Chemokines have recently been reported to be involved in pathological bone destruction. However, the physiological roles of chemokines in bone metabolism in vivo have not been well documented. We analyzed the bone phenotypes in Cx3cr1 -deficient mice. The mice exhibited slight but significant increases in trabecular and cortical thickness, reduced numbers of osteoclasts and increased rates of osteoid formation. Although the morphometric parameters showed marginal differences, the Cx3cr1 -deficient bones showed an elevated expression of Osterix/SP7 , which encodes an essential transcriptional factor for osteoblasts, whereas the gene Osteocalcin /Bglap , which encodes a late marker, was downregulated. The levels of transcripts for various osteoclastic markers, such as receptor activator of NF-κB (RANK)/TNFRSF11A, receptor activator of NF-κB ligand (RANKL)/TNFSF11, tartrate-resistant acid phosphatase 5b (TRAP5B)/ACP5B, Cathepsin K(CTSK), MMP3 and MMP13, were significantly decreased in the Cx3cr1 -deficient bones. Cultured Cx3cr1 -deficient osteoblastic cells showed inverse temporal patterns of osteoblastic marker expression and reduced calcium deposition. Furthermore, in vitro studies and immunofluorescence staining against CX3CR1 and CX3CL1 suggested a role for the CX3CR1–CX3CL1 axis in an early stage of osteoblast differentiation, possibly through their trans and cis interactions. Cultured Cx3cr1- deficient pre-osteoclasts showed impaired differentiation, mainly due to a deficiency of the CD115 + CD11b lo osteoclastogenic population of myeloid-lineage precursors. The treatment of bone-marrow-derived osteoclastic cultures with recombinant CX3CL1 at different time points suggested that the CX3CR1–CX3CL1 axis favors the maintenance of osteoclastic precursors, but not differentiated osteoclasts. These observations uncovered novel roles of the CX3CR1–CX3CL1 axis in the differentiation of both osteoblasts and osteoclasts.
Screening of a Supramolecular Catalyst Library in the Search for Selective Catalysts for the Asymmetric Hydrogenation of a Difficult Enamide Substrate (2006)

Für schwierige Kandidaten: Aus zwei einzähnigen Liganden (der eine beruht auf einem Zink(II)-porphyrin, der andere auf einem substituierten Phosphan) wurde mithilfe von Hochdurchsatzmethoden in Kombination mit Selbstorganisationsprinzipien eine große Zahl zweizähniger Liganden hergestellt. Die Bibliothek lieferte einen Rh-Katalysator, der das Enamid 1 mit der bislang höchsten Enantioselektivität hydriert. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2001/2006/z503663_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Observation of perpendicular exchange bias in[Pd∕Co]−CoOnanostructures: Dependence on size, cooling field, and training (2007)

Magnetic $[\mathrm{Pd}∕\mathrm{Co}]$ multilayer structures deposited onto self-assembled particle monolayers were capped with a CoO layer to study the size dependence of perpendicular exchange bias. Compared to the continuous film, the biased caps develop an asymmetric hysteresis loop and show a significantly higher exchange bias field and coercivity strongly depending on the cooling field and number of field cycles. The magnitude of the exchange bias field increases substantially as we scale down the particle diameter. Moreover, in contrast to the film, the coercivity exhibits a nonmonotonic temperature behavior with a local maximum at about $250\phantom{\rule{0.3em}{0ex}}\mathrm{K}$, which may originate from strong spin fluctuations in the antiferromagnet.
Postsynthetic Modification: An Enabling Technology for the Advancement of Metal–Organic Frameworks (2020)

Metal-organic frameworks (MOFs) are a class of porous materials with immense chemical tunability derived from their organic and inorganic building blocks. Presynthetic approaches have been used to construct tailor-made MOFs, but with a rather restricted functional group scope limited by the typical MOF solvothermal synthesis conditions. Postsynthetic modification (PSM) of MOFs has matured into an alternative strategy to broaden the functional group scope of MOFs. PSM has many incarnations, but two main avenues include (1) covalent PSM, in which the organic linkers of the MOF are modified with a reagent resulting in new functional groups, and (2) coordinative PSM, where organic molecules containing metal ligating groups are introduced onto the inorganic secondary building units (SBUs) of the MOF. These methods have evolved from simple efforts to modifying MOFs to demonstrate proof-of-concept, to becoming key synthetic tools for advancing MOFs for a range of emerging applications, including selective gas sorption, catalysis, and drug delivery. Moreover, both covalent and coordinative PSM have been used to create hierarchal MOFs, MOF-based porous liquids, and other unusual MOF materials. This Outlook highlights recent reports that have extended the scope of PSM in MOFs, some seminal reports that have contributed to the advancement of PSM in MOFs, and our view on future directions of the field.
Biphasic regulation of paracellular permeability in human cervical cells by two distinct nucleotide receptors (1995)

The effects of extracellular ATP (ATPe) were characterized in human cervical cells grown on filters. ATPe changed the transepithelial conductance (GT) in a biphasic manner with an initial acute increase of 13 +/- 3% (phase I), lasting approximately 2 min, followed by a sustained decrease of 49 +/- 17% (phase II). ATPe also effected decreases of permeabilities to pyranine and to sucrose, which correspond to the phase II decrease in GT. Both phase I and II effects appear to be mediated by apical nucleotide receptors. However, the phase I effect differed from the phase II effect as follows: 1) a higher 50% effective concentration for ATPe, 22 vs. 3 microM; 2) different nucleotide specificity; 3) lack of influence of pretreatment with pertussis toxin; 4) independence from time in culture after seeding; and 5) involvement of cytosolic calcium, rather than diacylglycerol, as intracellular messenger. These differences suggest the presence of two different types of nucleotide receptors that use different intracellular signaling systems and have opposite effects on the paracellular permeability and electrical conductance. These results suggest that ATPe could regulate cervical mucus production in vivo by regulating the paracellular permeability. Depending on the specific receptors present, ATPe could either increase or decrease mucus production.
Editorial Comment (1987)

No AccessJournal of Urology1 Oct 1987Editorial Comment Ralph V. Clayman Ralph V. ClaymanRalph V. Clayman More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(17)43388-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Editorial Comment." The Journal of Urology, 138(4 Part 1), p. 831 © 1987 by The American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 138Issue 4 Part 1October 1987Page: 831 Advertisement Copyright & Permissions© 1987 by The American Urological Association Education and Research, Inc.MetricsAuthor Information Ralph V. Clayman More articles by this author Expand All Advertisement PDF DownloadLoading ...
Conoscopic holography II Rigorous derivation (1992)

Conoscopic holography was discussed with simplifying assumptions in a companion paper [ J. Opt. Soc. Am. A.9, 70 ( 1992)]. These assumptions are removed, and the conclusions of the simplified analysis of the companion paper are proved by more exact calculations.
Silicon Photonics Based Transponder Aggregator for Next Generation ROADM Systems (2012)

After a brief review of the CDC-ROADM technologies for dynamic network systems, we demonstrate silicon photonics based transponder aggregators for 8-degree CDC-ROADM systems. Transponder aggregators in such systems play a key role in realization of the CDC function between multiple input/output fibers and multiple transponders.
L1CAM protein expression is associated with poor prognosis in non-small cell lung cancer (2011)

A subset of NSCLCs with vessel tropism and increased metastasis aberrantly expresses L1CAM. L1CAM is a novel prognostic marker for NSCLCs that is upregulated by EMT induction and appears to be instrumental for enhanced cell invasion.
Autonomy (2007)

Over a million Americans and Canadians have purchased a product called CortiSlim, which has been widely advertised on radio and television “infomercials.” Until restrained by the Federal Trade Commission in October 2004, the promoters claimed that taking CortiSlim caused
Supplementary Data from Three-Gene Expression Signature Predicts Survival in Early-Stage Squamous Cell Carcinoma of the Lung (2023)

Supplementary Data from Three-Gene Expression Signature Predicts Survival in Early-Stage Squamous Cell Carcinoma of the Lung
Compact transient thermal model for 3D ICs with liquid cooling via enhanced heat transfer cavity geometries (2010)

The advent of 3D stacked ICs with accumulating heat fluxes stresses thermal reliability and is responsible for temperature driven performance deterioration of the electronic systems Hot spots with power densities typically rising up to 250 W/cm2 are not acceptable, with the result of limited performance improvement in next generation highperformance microprocessor stacks. Unfortunately traditional back-side cooling only scales with the chip stack footprint, but not with the number of tiers. Direct heat removal from the IC dies via inter-tier liquid cooling is a promising solution to address this problem. In this regard, a thermal-aware design of a 3D IC with liquid cooling for optimal electronic performance and reliability requires fast modeling and simulation of the liquid cooling during the early stages of the design. In this paper, we propose a novel compact transient thermal modeling (CTTM) scheme for liquid cooling in 3D ICs via microchannels and enhanced heat transfer cavity geometries such as pin-fin structures. The model is compatible with the existing thermal- CAD tools for ICs and offers significant speed-up over commercial computational fluid dynamics simulators (13478x for pin-fin geometry with 1.1% error in temperature). In addition, the model is highly flexible and it provides a generic framework in which heat transfer coefficient data from numerical simulations or existing correlations can be incorporated depending upon the speed/accuracy needs of the designer. We have also studied the effects of using different techniques for the estimation of heat transfer coefficients on the accuracy of the model. This study highlights the need to consider developing flow conditions to accurately model the temperature field in the chip stack. The use of correlation data from fully developed flows only results in temperature error as high as 9 K (about 41%) near the inlet.
New alkylthio-thieno[3,2-b]thiophene-substituted benzodithiophene-based highly efficient photovoltaic polymer (2015)

We introduced an alkylthio-substituent on the thieno[3,2-<italic>b</italic>]thiophene side chain of the polymer and synthesized a new low band gap 2D-conjugated polymer, PSTTBDT-FTT.
Deanonymizing mobility traces (2012)

Location-based services, which employ data from smartphones, vehicles, etc., are growing in popularity. To reduce the threat that shared location data poses to a user's privacy, some services anonymize or obfuscate this data. In this paper, we show these methods can be effectively defeated: a set of location traces can be deanonymized given an easily obtained social network graph. The key idea of our approach is that a user may be identified by those she meets: a "contact graph" identifying meetings between anonymized users in a set of traces can be structurally correlated with a social network graph, thereby identifying anonymized users. We demonstrate the effectiveness of our approach using three real world datasets: University of St Andrews mobility trace and social network (27 nodes each), SmallBlue contact trace and Facebook social network (125 nodes), and Infocom 2006 bluetooth contact traces and conference attendees' DBLP social network (78 nodes). Our experiments show that 80% of users are identified precisely, while only 8% are identified incorrectly, with the remainder mapped to a small set of users.
Proceedings of the 6th ACM conference on Electronic commerce (2005)

The papers in these proceedings were presented at the 2005 ACM Conference on Electronic Commerce, held June 5-8 in Vancouver, Canada. These papers were selected from 113 submissions in areas relevant to electronic commerce. The papers were selected by a program committee of 21 experts in the field.The selection process started shortly after the submission deadline of December 7, 2004. At least three program committee members were assigned to evaluate each paper's scientific novelty, technical quality, and importance to the field. Final selection of the 32 papers that appear in these proceedings was based on these reviews and deliberations among the program committee.
Soluble Receptor-Mediated Targeting of Mouse Hepatitis Coronavirus to the Human Epidermal Growth Factor Receptor (2005)

The mouse hepatitis coronavirus (MHV) infects murine cells by binding of its spike (S) protein to murine CEACAM1a. The N-terminal part of this cellular receptor (soR) is sufficient for S binding and for subsequent induction of the conformational changes required for virus-cell membrane fusion. Here we analyzed whether these characteristics can be used to redirect MHV to human cancer cells. To this end, the soR domain was coupled to single-chain monoclonal antibody 425, which is directed against the human epidermal growth factor receptor (EGFR), resulting in a bispecific adapter protein (soR-425). The soR and soR-425 proteins, both produced with the vaccinia virus system, were able to neutralize MHV infection of murine LR7 cells. However, only soR-425 was able to target MHV to human EGFR-expressing cancer cells. Interestingly, the targeted infections induced syncytium formation. Furthermore, the soR-425-mediated infections were blocked by heptad repeat-mimicking peptides, indicating that virus entry requires the regular S protein fusion process. We conclude that the specific spike-binding property of the CEACAM1a N-terminal fragment can be exploited to direct the virus to selected cells by linking it to a moiety able to bind a receptor on those cells. This approach might be useful in the development of tumor-targeted coronaviruses.
Are Females at Greater Risk for Revision Surgery After Hip Resurfacing Arthroplasty With the Articular Surface Replacement Prosthesis? (2016)

Level II, therapeutic study.
Environmental Agent Susceptibility Assessment Using Existing and Novel Biomarkers as Rapid Noninvasive Testing Methods (2005)

This study is part of a project aimed at developing and validating novel noninvasive methods for the detection of biomarkers of endocrine disrupters (EDs) directly in the mucus of aquatic species, to identify novel functional biomarker(s) for EDs, and to verify their applicability for field studies. The multidisciplinary approach chosen aims at the development of an integrated testing strategy utilizing in vitro protocols to identify water and sediment fractions with potential endocrine-disrupting activity; the identification, characterization, and measurement of new biomarker(s) for EDs; the development and validation of a dipstick-based test method; and the development of (computer-assisted) predictive models. Some results of the first year of the project are presented here.
ChemInform Abstract: Lessons from the Pseudorotational Cycle: Conformationally Rigid AZT Carbocyclic Nucleosides and Their Interaction with Reverse Transcriptase. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.