gebhart/patrepeval huggingface dataset:
Multimedia Marketing for Design Firms (1996)

Desktop Publishing. Visualization Tools. Desktop Digital Video. Online Marketing. Multimedia. Delivery Media. Multimedia Marketing in Action. Index. About the CD--ROM.
N-Hydroxypyridine-2(1H)-thione:  Not a Selective Generator of Hydroxyl Radicals in Aqueous Solution (1996)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTN-Hydroxypyridine-2(1H)-thione: Not a Selective Generator of Hydroxyl Radicals in Aqueous SolutionBéatrice M. Aveline, Irene E. Kochevar, and Robert W. RedmondView Author Information Wellman Laboratories of Photomedicine Department of Dermatology, Harvard Medical School Massachusetts General Hospital Boston, Massachusetts 02114 Cite this: J. Am. Chem. Soc. 1996, 118, 1, 289–290Publication Date (Web):January 10, 1996Publication History Received27 September 1995Published online10 January 1996Published inissue 1 January 1996https://doi.org/10.1021/ja953293iCopyright © 1996 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views292Altmetric-Citations19LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (109 KB) Get e-AlertsSUBJECTS:Absorption,Irradiation,Lasers,Photoionization,Solution chemistry Get e-Alerts
A thermally robust and strongly oxidizing surface of WO3hydrate nanowires for electrical aldehyde sensing with long-term stability (2021)

Thermally robust and strongly oxidizing surface is created by a simple strong acid treatment on WO<sub>3</sub>hydrate nanowires, which enables integrated nanosensors to operate with a superior sensing performance to aldehyde molecules with long-term stability.
Ablation of Severe Drug‐Resistant Tachyarrhythmia During Pregnancy (2010)

Ablation can be performed safely with no or minimal radiation exposure during pregnancy. In the setting of malignant, drug-resistant arrhythmia, ablation may be considered a therapeutic option in selected cases.
Covalent Allosteric Probe for the Metabotropic Glutamate Receptor 2: Design, Synthesis, and Pharmacological Characterization (2018)

Covalent labeling of G protein-coupled receptors (GPCRs) by small molecules is a powerful approach to understand binding modes, mechanism of action, pharmacology, and even facilitate structure elucidation. We report the first covalent positive allosteric modulator (PAM) for a class C GPCR, the mGlu<sub>2</sub> receptor. Three putatively covalent mGlu<sub>2</sub> PAMs were designed and synthesized. Pharmacological characterization identified 2 to bind the receptor covalently. Computational modeling combined with receptor mutagenesis revealed T791<sup>7.29×30</sup> as the likely position of covalent interaction. We show how this covalent ligand can be used to characterize the PAM binding mode and that it is a valuable tool compound in studying receptor function and binding kinetics. Our findings advance the understanding of the mGlu<sub>2</sub> PAM interaction and suggest that 2 is a valuable probe for further structural and chemical biology approaches.
Endothelial Zeb2 preserves the hepatic angioarchitecture and protects against liver fibrosis (2021)

Endothelial Zeb2 preserves liver angioarchitecture and protects against liver fibrosis. Zeb2 and Zeb2-dependent genes in liver ECs may be exploited to design novel therapeutic strategies to attenuate hepatic fibrosis.
Improving the mode profile circularity of microstructured optical fibers by using an Archimedean-like cladding structure (2008)

We present a novel microstructured optical fiber (MOF) structure which consists of a 7-missing-holes core surrounded by a cladding formed by an Archimedean-like lattice of air holes, as opposed to the standard MOF cladding structure consisting of a triangular lattice. We demonstrate that this new cladding geometry can be achieved through the standard stack-and-draw MOF fabrication method, the main difference being the fact that the circular capillaries commonly used in conventional MOF are replaced by hexagonal canes comprising 7 air holes disposed in a centred hexagon (forming the so-called A7 unit cells). The <i>Archimedean-like lattice MOF </i>(ALMOF) is particularly interesting by the fact that it features a dodecagonal core, which is a shape much closer to a perfect circle than the hexagonally-shaped core characteristic of the conventional 7-missing-holes triangular-lattice MOF. As a result, we show that the improved core circularity of the ALMOF design leads to a significantly more circular fundamental mode profile, which can prove to be quite interesting for specific applications where the circularity of the mode profile is critical, such as precision laser micromachining for example.
A simplified model for XPM in coherent PSK systems (2010)

A simplified model is proposed to facilitate cross-phase modulation (XPM) analysis in coherent PSK systems. It is verified by a 43Gb/s QPSK simulation in terms of phase noise standard deviation, autocorrelation and system performance.
vHaul: Towards Optimal Scheduling of Live Multi-VM Migration for Multi-tier Applications (2015)

Live virtual machine (VM) migration enables seamless movement of an online server from one location to another to achieve failure recovery, load balancing, and system maintenance. Beyond single VM migration, a multi-tier application involves a group of correlated VMs and its live migration will require careful scheduling of the migrations of the member VMs. Our observations from extensive experiments using a variety of multi-tier applications suggest that, in a dedicated data center with dedicated migration links, different migration strategies result in distinct performance impacts on a multi-tier application. The root cause of the problem is the inter-dependence between functional components of a multitier application. We leverage these observations in vHaul, a system that coordinates multi-VM migration to approximate the optimal scheduling. Our evaluation of a vHaul prototype on Xen suggests that vHaul yields the optimal multi-VM live migration schedules. Further, our application-level evaluation using Apache Olio, a web 2.0 cloud application, shows that the optimal migration schedule produced by vHaul outperforms the worst-case schedule by 43% in application throughput. Moreover, the optimal schedule significantly reduces service latency during migration by up to 70%.
Guinea pig lymphotoxin (LT). I. In vitro studies of LT produced in response to antigen stimulation of lymphocytes. (1973)

Lymphotoxin (LT) was found to be present in the same supernatants as antigen-stimulated guinea pig lymphocytes in which migration-inhibitory factor (MIF) was found. LT activity was determined by staining target cells with trypan blue, counting the cells present in the media and determining their viability, direct observation by time-lapse cinematography and measuring protein synthesis by surviving target cells. Like migration-inhibitory factor, the induction of LT release was antigen specific. LT was effective on a number of different target cell lines; however, young cultures of guinea pig embryo fibroblasts were resistant to it.
Transactivation Ability of p53 Transcriptional Activation Domain Is Directly Related to the Binding Affinity to TATA-binding Protein (1995)

Tumor suppressor protein p53 is a potent transcriptional activator and regulates cell growth negatively. To characterize the transcriptional activation domain (TAD) of p53, various point mutants were constructed in the context of Gal4 DNA binding domain and tested for their transactivation ability. Our results demonstrated that the positionally conserved hydrophobic residues shared with herpes simplex virus VP16 and other transactivators are essential for transactivation. Also, the negatively charged residues and proline residues are necessary for full activity, but not essential for the activity of p53 TAD. Deletion analyses showed that p53 TAD can be divided into two subdomains, amino acids 1-40 and 43-73. An in vitro glutathione S-transferase pull-down assay establishes a linear correlation between p53 TAD-mediated transactivation in vivo and the binding activity of p53 TAD to TATA-binding protein (TBP) in vitro. Mutations that diminish the transactivation ability of Gal4-p53 TAD also impair the binding activity to TBP severely. Our results suggest that at least TBP is a direct target for p53 TAD and that the binding strength of TAD to TBP (TFIID) is an important parameter controlling activity of p53 TAD. In addition, circular dichroism spectroscopy has shown that p53 TAD peptide lacks any regular secondary structure in solution and that there is no significant difference between the spectra of the wild type TAD and that of the transactivation deficient mutant type.
K/πFluctuations at Relativistic Energies (2009)

We report K/pi fluctuations from Au + Au collisions at sqrt[s(NN)]= 19.6, 62.4, 130, and 200 GeV using the STAR detector at the Relativistic Heavy Ion Collider. K/pi fluctuations in central collisions show little dependence on incident energy and are on the same order as those from NA49 at the Super Proton Synchrotron in central Pb + Pb collisions at sqrt[s(NN)]=12.3 and 17.3 GeV. We report results for the collision centrality dependence of K/pi fluctuations and results for charge-separated fluctuations. We observe that the K/pi fluctuations scale with the charged particle multiplicity density.
Supplemental Figures from The Impact of Smoking and TP53 Mutations in Lung Adenocarcinoma Patients with Targetable Mutations—The Lung Cancer Mutation Consortium (LCMC2) (2023)

&lt;p&gt;Supplementary Figure 1 Sample Analysis Flowchart Supplementary Figure 2 LOMC2 Gene List Supplementary Figure 3 PTEN Immunohistochemistry analysis of LCMC II samples. Supplementary Figure 4 Mutation Frequency by Mutation and Smoking Status&lt;/p&gt;
Dielectric powder loaded coaxial-cavity filters (2017)

In this paper we demonstrate the use of low-loss dielectric powders in the design and fabrication of RF filters. Initially, several different powders are tested for their RF performance - in particular their relative dielectric permittivity and loss tangent. Then, based on the information obtained in this way, the best performance powder is used to design a 5-pole Chebyshev filter operating at a centre frequency of 779 MHz, with a bandwidth of 17 MHz. Upon fabrication of the filter housing, the filter cavities are filled with the powder. Compaction of the powders is achieved in a systematic way and has resulted in stable performance.
All-optical XOR gate based on Kerr effect in single highly-nonlinear fiber (2004)

We demonstrate an all-optical XOR gate based on Kerr effect in a single highly-nonlinear fiber. We obtain a 25 dB extinction ratio using 2-km of highly-nonlinear fiber with a nonlinear coefficient of 9.1 W/sup -1/km/sup -1/.
Performance Analysis of Optimum Combining in Antenna Array Systems With Multiple Interferers in Flat Rayleigh Fading (2004)

In this letter, we examine the statistical distribution of the signal-to-interference-plus-noise ratio (SINR) of the optimum combining (OC) technique in receive-antenna diversity systems. We decompose the SINR into two components by projection onto the interference subspace for systems with more antennas than interferers. For the case when the number of interferers is larger than the number of antennas, upper and lower bounds on performance are provided.
On Large-Batch Training for Deep Learning: Generalization Gap and Sharp Minima (2016)

The stochastic gradient descent (SGD) method and its variants are algorithms of choice for many Deep Learning tasks. These methods operate in a small-batch regime wherein a fraction of the training data, say $32$-$512$ data points, is sampled to compute an approximation to the gradient. It has been observed in practice that when using a larger batch there is a degradation in the quality of the model, as measured by its ability to generalize. We investigate the cause for this generalization drop in the large-batch regime and present numerical evidence that supports the view that large-batch methods tend to converge to sharp minimizers of the training and testing functions - and as is well known, sharp minima lead to poorer generalization. In contrast, small-batch methods consistently converge to flat minimizers, and our experiments support a commonly held view that this is due to the inherent noise in the gradient estimation. We discuss several strategies to attempt to help large-batch methods eliminate this generalization gap.
Co-immobilization of chitosan and dermatan sulfate from Raja montagui skin on polyethylene terephthalate surfaces: Characterization and antibiofilm activity (2017)

In this work, polyethylene terephthalate (PET) was chemically modified by covalent co-immobilization of two separate layers of bioactive polymers composed of chitosan and a new dermatan sulfate isolated from Raja montagui skin. The new materials obtained were characterized by determination of carboxyl groups, ATR-FTIR spectroscopy, drop water contact angle, SEM, and TGA measurements. The different immobilizations modified the surface characteristics; especially when the first layer was dermatan sulfate (PET–DS–Chito) which presented the best surface wettability (71 ± 3°). It also reduced the ability of Staphylococcus epidermidis to form biofilm on PET surfaces which could decrease the virulence of vascular prosthesis infections.
Design and implementation of a lightweight high-voltage power converter for electro-aerodynamic propulsion (2017)

Recent studies in electro-aerodynamic (EAD) propulsion have stimulated the need for lightweight power converters providing outputs at tens of kilovolts and hundreds of watts. This paper demonstrates a design of a lightweight high-voltage converter operating from a 160-200 V dc input and providing dc output of up to 600 W at 40 kV. It operates at around 500 kHz and achieves a specific power of 1.2 kW/kg. This is considerably lighter than comparable industrial and academic designs at this power level. High voltage converters generally comprise an inverter, a step-up transformer and a rectifier, with the large needed voltage gain distributed among these stages. Several means of realizing these stages are compared in terms of weight. The weight of the converter is minimized by properly selecting and optimizing the design and the voltage gain of each stage within the constraints of device limitations and losses. A prototype circuit is developed based on this approach and used to drive an EAD-propulsion system for an unmanned aerial vehicle (UAV). In addition to addressing the power conversion needs for EAD, this research can potentially benefit the development of lightweight high-voltage converters in many other applications where weight and size are important.
Bomberman: Defining and Defeating Hardware Ticking Timebombs at Design-time (2021)

To cope with ever-increasing design complexities, integrated circuit designers increase both the size of their design teams and their reliance on third-party intellectual property (IP). Both come at the expense of trust: it is computationally infeasible to exhaustively verify that a design is free of all possible malicious modifications (i.e., hardware Trojans). Making matters worse, unlike software, hardware modifications are permanent: there is no "patching" mechanism for hardware; and powerful: they serve as a foothold for subverting software that sits above.To counter this threat, prior work uses both static and dynamic analysis techniques to verify hardware designs are Trojan-free. Unfortunately, researchers continue to reveal weaknesses in these "one-size-fits-all", heuristic-based approaches. Instead of attempting to detect all possible hardware Trojans, we take the first step in addressing the hardware Trojan threat in a divide-and-conquer fashion: defining and eliminating Ticking Timebomb Trojans (TTTs), forcing attackers to implement larger Trojan designs detectable via existing verification and side-channel defenses. Like many system-level software defenses (e.g., Address Space Layout Randomization (ASLR) and Data Execution Prevention (DEP)), our goal is to systematically constrict the hardware attacker’s design space.First, we construct a definition of TTTs derived from their functional behavior. Next, we translate this definition into fundamental components required to realize TTT behavior in hardware. Using these components, we expand the set of all known TTTs to a total of six variants—including unseen variants. Leveraging our definition, we design and implement a TTT-specific dynamic verification toolchain extension, called Bomber-man. Using four real-world hardware designs, we demonstrate Bomberman’s ability to detect all TTT variants, where previous defenses fail, with <1.2% false positives.
ChemInform Abstract: Dynamic Behavior of Dicobalt Hexacarbonyl Propargyl Cations and Their Reactions with Chiral Nucleophiles. (1988)

Abstract The dynamic behavior of several dicobalt hexacarbonyl propargyl cations is investigated by variable temp. 1 H and 13 C NMR methods.
Hybrid 224-Gb/s and 112-Gb/s PDM-QPSK Transmission at 50-GHz Channel Spacing over 1200-km Dispersion-Managed LEAF® Spans and 3 ROADMs (2011)

We transmit a mix of 224-Gb/s and 112-Gb/s PDM-QPSK channels at a 50-GHz spacing and 3-b/s/Hz spectral efficiency over 1200-km dispersion-managed LEAF® spans with 3 ROADMs and over 2000 km without ROADMs.
Supplementary Table 2 from A 12-Gene Set Predicts Survival Benefits from Adjuvant Chemotherapy in Non–Small Cell Lung Cancer Patients (2023)

&lt;p&gt;PDF file - 64K, Meta-analysis of 18-hub-gene prognostic signature on ADC patients and SCC patients.&lt;/p&gt;
Loosely Coupled Transformer Coil Design to Minimize EMF Radiation in Concerned Areas (2016)

Wireless power transfer (WPT) technology as a convenient and reliable charging method, its electromagnetic field (EMF) radiation, and its compliance with human electromagnetic exposure limits have recently been studied. Different from the current research, which validates the EMF radiation level of a predesigned WPT system, this paper presents the loosely coupled transformer design method to minimize the EMF in the concerned area. The energy storage in the primary and secondary coils is studied for all popular compensation topologies in recently reported research. The coil of the loosely coupled transformer is designed with the S-S compensation topology as an example. The EMF radiation level is optimized to below the International Commission on Non-Ionizing Radiation Protection guideline in the concerned area. A 3.3-kW WPT system for electric vehicle wireless charging with an LCC-LCC compensation topology is designed with detailed process and experiment results, verifying that the EMF radiation is controlled as designed. The numerical analysis of human exposure is performed with the finite-element method, and the results show compliance as expected.
Gas Separation by Polymer Membranes (2016)

Different aspects related to the technology and industrial application of polymer membranes starting from materials research, to the module design and their optimal configuration in membrane systems used for enhancing process performance have been extensively reviewed in the literature. Numeric simulations methods representing gas transport phenomena at different scales based on new simulation protocols strongly contribute to the acceleration of the R&D search and implementation of new concepts in industrial gas separation by membrane technology. Although there is still room for improvement in process design and operation of membranes, most gains in process efficiency will likely come from the development of new and improved membrane materials and technologies that will allow their scale-up into industrial fabrication processes.
Plasmonic Nanoantenna Array with Single-Chip Integrated Metal-Organic Framework for Infrared Absorption Gas Sensing (2016)

Plasmonics devices are usually not suitable for gas spectroscopy due to the limited enhancement length for absorption. Here, we demonstrate a plasmonic nanopatch array coated with metal-organic framework (MOF) for surface enhanced infrared absorption to detect carbon dioxide. The highest enhancement factor we achieved is over 1100 times.
Quantum size effect in δ-doped AlGaAs heterostructures (1988)

We report a new structure formed by δ doping the barrier of an AlGaAs heterostructure. Our structure contains a pair of electronically coupled quantum systems that develop from the quantum size effect occurring in the barrier and at the heterointerface. Compared to conventional homogeneous doping, we find enhancements in interface density resulting in δ-doped structures for all spacer thicknesses. A mobility of 1.9×106 cm2/V s is observed at a spacer layer thickness of 360 Å. Systematic dependences of interface mobility and density on spacer thickness are deduced from the quantum Hall effect and variable temperature Hall measurements.
A Fully Integrated 60-GHz CMOS Transceiver Chipset Based on WiGig/IEEE 802.11ad With Built-In Self Calibration for Mobile Usage (2013)

This paper presents a fully integrated transceiver chipset based on the WiGig/IEEE 802.11ad standard targeting mobile usage. The chipset is developed for single-carrier (SC) modulation, which is suitable for reduced power consumption. However, the SC modulation is sensitive to in-band amplitude variations, mainly made worse by the gain variations of analog circuits and multipath delay spread. In order to compensate for these gain variations, the proposed chipset employs built-in TX in-band calibration and an RX frequency domain equalizer (FDE). The proposed techniques relax the requirement for high speed analog circuits, leading to less power consumption while minimizing the increase of hardware size. The test chip achieves 1.8 Gb/s MAC throughput for up to 40 cm and 1.5 Gb/s for up to 1 m while consuming 788 mW in TX and 984 mW in RX mode.
Predictability of radiographic diagnosis of variations in root canal anatomy in mandibular incisor and premolar teeth (1991)

Four hundred and fifty-five extracted mandibular incisor and 340 extracted mandibular premolar teeth were radiographed to assess the incidence of twin canals as visualized on radiographs taken in the mesio-distal direction. The ability to detect the presence of these twin canals by viewing radiographs taken in the standard bucco-lingual direction was then assessed. Using the guideline that 'disappearance or narrowing infers division' when viewing these radiographs resulted in a failure to diagnose one-third of the twin canals.