gebhart/patrepeval huggingface dataset:
Luminescent Pt(ii) complexes bearing dual isoquinolinyl pyrazolates: fundamentals and applications (2014)

A series of four Pt(II) metal complexes with trans-arranged isoquinolinyl azolates have been prepared, [Pt(Lx)2], x = 1-4, (1-4). The associated chelates possess various substituents; namely: one t-butyl (Bu(t)) at the 6-position (L1), two Bu(t) groups at the 5,7-positions (L2), one dip (2,6-di-isopropylphenyl) group at the 6-position (L3), and a single dip group at the 4-position of the 1-isoquinolinyl fragment (L4), respectively. Crystal structures of 1 and 4 were determined to shed light on the relationship of photophysics and packing arrangements. Their photophysical properties were measured and compared, for which the solid-state emission spectra of 2 and 4 are nearly identical to the solution spectra of all the Pt(II) complexes, showing the formation of isolated molecular entities. In contrast, the Pt(II) complexes 1 and 3 are found to be sensitive to their morphological states and external stimulus. This is confirmed by the gradual red-shifting of the emission with increasing concentration in the PMMA matrix, and the eventual formation of the broadened, metal-metal-to-ligand charge transfer (MMLCT) emission, by (i) wetting with acetone and drying in air, or (ii) grinding with a mortar and pestle, respectively. Organic light-emitting diodes (OLEDs) were also fabricated using multiple layered architecture and lowered doping concentration (e.g. 8 wt%), the latter is for avoiding dopant aggregation in the emitting layer. The associated OLED performances (i.e. η(max) = 11.5%, 8.5%, and 11.2% for 1, 2 and 3) confirmed their suitability and potential as dopants for phosphorescent OLEDs.
Predictors of treatment response to intravitreal anti-vascular endothelial growth factor (anti-VEGF) therapy for choroidal neovascularisation secondary to chronic central serous chorioretinopathy (2019)

The anti-VEGF response was highly variable and often incomplete, suggesting that CNV was not solely responsible for the fluid accumulation. Predictive factors may guide indication for anti-VEGF in CNV associated with CSC.
25.4: A Laser‐Based Digital Cinema Projector (2011)

Abstract A fully functional DCI capable prototype Laser Digital Cinema Projector has been developed by Eastman Kodak Company using an innovative optical architecture. The prototype demonstrates the potential of the long life and lower operational costs of lasers while minimizing the incremental costs to manufacture. The projector provides over 10,000:1 contrast ratio, an increased color gamut, and an integrated 3D capability that is significantly brighter than is common today in cinema. These attributes are delivered while addressing the impact of laser speckle, eye safety, and other potential impediments to commercialization.
Highly Oxidized Ecdysteroids from a Commercial Cyanotis arachnoidea Root Extract as Potent Blood–Brain Barrier Protective Agents (2023)

Ecdysteroid-containing herbal extracts, commonly prepared from the roots of <i>Cyanotis arachnoidea</i>, are marketed worldwide as a "green" anabolic food supplement. Herein are reported the isolation and complete <sup>1</sup>H and <sup>13</sup>C NMR signal assignments of three new minor ecdysteroids (compounds <b>2</b>-<b>4</b>) from this extract. Compound <b>4</b> was identified as a possible artifact that gradually forms through the autoxidation of calonysterone. The compounds tested demonstrated a significant protective effect on the blood-brain barrier endothelial cells against oxidative stress or inflammation at a concentration of 1 μM. Based on these results, minor ecdysteroids present in food supplements may offer health benefits in various neurodegenerative disease states.
Time- and load- dependent behaviour of flowable concrete: Progress report of fib task group 4.3 (2015)

Stress and strain interaction is of vital importance for concrete structures as it has an influence on cracking, deflection and prestressing loss. With the increased range of compressive strengths and flow characteristics, the mixture composition of nowadays concretes often differs considerably from Vibrated Concrete (VC) with regard to paste strength, paste composition and paste volume. This paper discusses time- and load-dependent characteristics of flowable concrete as an outcome of a workgroup within fib Task Group 4.3 that aims at facilitating the use of innovative flowable materials for the design of concrete structures.
WaveCloud : an open source room acoustics simulator using the finite difference time domain method (2014)

Among the various wave-based simulation methods, the finite difference time domain (FDTD) method provides a good trade-off between applicability, accuracy and computational efficiency. With the growing availability of computing power and recent advances in parallel architectures, FDTD has become a feasible choice for room acoustics simulation. Operating in the discrete time domain, it is advantageous for obtaining wideband solutions within a single simulation, and is also able to tackle problems involving transient behavior and time variability, for example with moving sources, moving receivers and a moving medium. This paper portrays the WaveCloud Project, an open-source modeling framework designed with room acoustics simulation in mind. Practical concerns such as computation time, handling arbitrary room geometries, and modeling directional sources and receivers are addressed and their current implementations in WaveCloud are discussed. Consideration is also given to three-dimensional sound field visualization as well as auralization strategies. Future work and remaining challenges, which now form part of the collaborative open source Wave Cloud project, are also described.
Bolocam 1.1-millimeter Galaxy Survey of the Lockman Hole (2004)

Submillimeter galaxies are extremely luminous (&gt; 1012 Lsolar), high redshift (z &gt; 1) galaxies detected by their thermal dust emission. If powered by star formation, extreme star formation rates are 102-10^3 Msolar per year are implied. Characterizing submillimeter galaxies is crucial to understanding galaxy formation and evolution. Cumulatively, surveys to date have detected hundreds of these galaxies.&#13;\nBolocam is a millimeter-wavelength bolometer-array camera designed for mapping large fields. This survey uses Bolocam to detect submillimeter galaxies at the bright end of the luminosity function. Due to the strong negative K-correction at 1.1 mm, Bolocam's detection sensitivity is approximately uniform for galaxies of a given intrinsic luminosity for redshifts 1 &lt; z &lt; 10.&#13;\n&#13;\nWe present results from our 1.1 mm galaxy survey made with the Caltech Submillimeter Observatory during January and May 2003. In total, 17 source candidates were detected at a significance of &gt; 3.0σ . Nine candidates are new detections, while 8 candidates have coincident SCUBA 850 μ m and/or MAMBO 1.2 mm detections. Monte-Carlo simulations with real and simulated data were implemented to confirm the robustness of our source candidates, quantify our false detection rate, determine our detection threshold and completeness of this survey, and estimate the impact of source confusion. From our observed number counts, we estimate the underlying differential number count distribution and find it to be in general agreement with previous surveys. We combine our source catalog with those from previous submillimeter and radio surveys and estimate redshifts for these sources.&#13;\n&#13;\nThis research is funded in part by grants from NASA (NGT5-50384), NSF (AST-9980846, AST-0206158, AST-0098737), and PPARC (PPA/Y/S/2000/00101, PPA/G/O/2002/00015)
Global evolution of influenza A viruses in swine (2016)

Influenza A viruses (IAVs) cause one of the most important viral respiratory diseases in pigs. Repeated outbreaks and spread of genetically and antigenically distinct IAVs represent considerable challenges for animal production. Subtypes of H1N1, H1N2, and H3N2 are currently endemic in swine around the world, but they exhibit substantial diversity not only within the hemagglutinin (HA) and neuraminidase (NA) genes, but also in the other six gene segments. Human and swine IAVs have had a particular propensity for bidirectional interspecies transmission during the past century, demonstrated by regular virus incursion between the two hosts, and sometimes sustained virus circulation within the new host species. The diversity of IAV in swine remains a critical challenge in diagnosis and control of this important pathogen, both for swine health, and as a result of zoonotic risk to public health.
Gasserian Ganglion and Retrobulbar Nerve Block in the Treatment of Ophthalmic Postherpetic Neuralgia: A Case Report (2016)

To our knowledge, this is the first reported case of ophthalmic division PHN successfully treated with a combination of trigeminal ganglion and retrobulbar nerve block using a local anesthetic agent and steroid for central and peripheral neural inflammatory processes.
N-Protected tripeptide inhibitors of angiotensin converting enzyme. (1990)

In our previous report,1] the effectiveness of substituted benzoyl Phe-Ala-Pro-OH as inhibitors of angiotensin converting enzyme (ACE) was explored, in which p-methoxy and /?-hydroxy benzoyl Phe-Ala-Pro-OH (X and XI) had
Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity (2016)

Obesity favours the occurrence of locally disseminated prostate cancer in the periprostatic adipose tissue (PPAT) surrounding the prostate gland. Here we show that adipocytes from PPAT support the directed migration of prostate cancer cells and that this event is strongly promoted by obesity. This process is dependent on the secretion of the chemokine CCL7 by adipocytes, which diffuses from PPAT to the peripheral zone of the prostate, stimulating the migration of CCR3 expressing tumour cells. In obesity, higher secretion of CCL7 by adipocytes facilitates extraprostatic extension. The observed increase in migration associated with obesity is totally abrogated when the CCR3/CCL7 axis is inhibited. In human prostate cancer tumours, expression of the CCR3 receptor is associated with the occurrence of aggressive disease with extended local dissemination and a higher risk of biochemical recurrence, highlighting the potential benefit of CCR3 antagonists in the treatment of prostate cancer.
Distributed Full-Duplex via Wireless Side-Channels: Bounds and Protocols (2013)

In this paper, we study a three-node full-duplex network, where a base station is engaged in simultaneous up- and downlink communication in the same frequency band with two half-duplex mobile nodes. To reduce the impact of inter-node interference between the two mobile nodes on the system capacity, we study how an orthogonal side-channel between the two mobile nodes can be leveraged to achieve full-duplex-like multiplexing gains. We propose and characterize the achievable rates of four distributed full-duplex schemes, labeled bin-and-cancel, compress-and-cancel, estimate-and-cancel and decode-and-cancel. Of the four, bin-and-cancel is shown to achieve within 1 bit/s/Hz of the capacity region for all values of channel parameters. In contrast, the other three schemes achieve the near-optimal performance only in certain regimes of channel values. Asymptotic multiplexing gains of all proposed schemes are derived to show that the side-channel is extremely effective in regimes where inter-node interference has the highest impact.
Purification of molybdenum, growth and characterization of medium volume ZnMoO4crystals for the LUMINEU program (2014)

The LUMINEU program aims at performing a pilot experiment on neutrinoless double beta decay of 100Mo using radiopure ZnMoO4 crystals operated as cryogenic scintillating bolometers. Growth of high quality radiopure crystals is a complex task, since there are no commercial molybdenum compounds available with the required level of purity and radioactive contamination. This paper discusses approaches to purify molybdenum and synthesize compounds for high quality radiopure ZnMoO4 crystal growth. A combination of a double sublimation (with addition of zinc molybdate) with subsequent recrystallization in aqueous solutions (using zinc molybdate as a collector) was used. Zinc molybdate crystals up to 1.5 kg were grown by the low-thermal-gradient Czochralski technique; their optical, luminescent, diamagnetic, thermal and bolometric properties were tested.
Extracellular–Intracellular Distribution of Glucose and Lactate in the Rat Brain Assessed Noninvasively by Diffusion-Weighted 1H Nuclear Magnetic Resonance Spectroscopy In Vivo (2000)

To determine the distribution of cerebral glucose and lactate between the intracellular and the extracellular space of the rat brain in vivo, the diffusion characteristic of glucose and lactate was compared with that of metabolites known to be mainly intracellular (N-acetylaspartate, choline, creatine, glutamate, myo-inositol, and taurine) using a pulsed-field-gradient 1H nuclear magnetic resonance technique. The detection of a glucose signal at large diffusion weighting provided direct experimental evidence of intracellular glucose in the rat brain. At large diffusion weighting, the apparent diffusion coefficient (ADC) of glucose and lactate was similar to that of the intracellular metabolites such as N-acetylaspartate, creatine, and glutamate. At small diffusion weighting, the ADC of glucose and lactate was increased, which was explained by a decreased relative contribution of intracellular glucose to the total signal. The calculated extracellular volume fraction of glucose (0.19 +/- 0.05) and lactate (0.17 +/- 0.06) was consistent with a substantial fraction of glucose and lactate signals being intracellular. The findings were direct in vivo evidence that the largest concentration gradient of glucose is at the blood-brain barrier and that glucose is evenly distributed in the brain in vivo between the intracellular and extracellular space.
Antibacterial Nanostructured Surfaces Modulate Protein Adsorption, Inflammatory Responses, and Fibrous Capsule Formation (2022)

The present study interrogates the interaction of highly efficient antibacterial surfaces containing sharp nanostructures with blood proteins and the subsequent immunological consequences, processes that are of key importance for the fate of every implantable biomaterial. Studies with human serum and plasma pointed to significant differences in the composition of the protein corona that formed on control and nanostructured surfaces. Quantitative analysis using liquid chromatography-mass spectrometry demonstrated that the nanostructured surface attracted more vitronectin and less complement proteins compared to the untreated control. In turn, the protein corona composition modulated the adhesion and cytokine expression by immune cells. Monocytes produced lower amounts of pro-inflammatory cytokines and expressed more anti-inflammatory factors on the nanostructured surface. Studies using an in vivo subcutaneous mouse model showed reduced fibrous capsule thickness which could be a consequence of the attenuated inflammatory response. The results from this work suggest that antibacterial surface modification with sharp spike-like nanostructures may not only lead to the reduction of inflammation but also more favorable foreign body response and enhanced healing, processes that are beneficial for most medical devices implanted in patients.
Metagenomic Analysis of Intestinal Microbiomes in Chickens (2011)

The digestive tract of animals contains a very large numbers of microorganisms with a high diversity. Traditionally, characterization of these microbial communities has relied on the ability to clonally culture each microorganism. With significant improvements in nucleotide sequencing technologies to economically obtain billions of bases, the study of genetic material recovered directly from environmental samples is becoming increasingly affordable. The investigation of microorganisms as a community regardless of their ability to be cultured has become reality. Using the metagenomic approach for analysis of chicken intestinal homogenates, we were able to greatly enhance the understanding of communities of microorganism in healthy and Runting Stunting Syndrome-infected chickens. In particular, comparative analysis of metagenomes from infected and noninfected chickens resulted in the identification of microorganisms as pathogen candidates. In this chapter, we demonstrate step-by-step how tools for comparative metagenomic analysis can facilitate the resolution of complex, multifactor-involved diseases.
Reversible 3 + 2 cycloaddition of ethylene to the C:Re.tplbond.C unit in rhenium complexes of the type Re(.tplbond.CCMe3)(:CHR')(OR)2 (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReversible 3 + 2 cycloaddition of ethylene to the C:Re.tplbond.C unit in rhenium complexes of the type Re(.tplbond.CCMe3)(:CHR')(OR)2G. Alan Vaughan, Robert Toreki, Richard R. Schrock, and William M. DavisCite this: J. Am. Chem. Soc. 1993, 115, 7, 2980–2981Publication Date (Print):April 1, 1993Publication History Published online1 May 2002Published inissue 1 April 1993https://doi.org/10.1021/ja00060a058RIGHTS & PERMISSIONSArticle Views218Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (183 KB) Get e-AlertsSupporting Info (3)»Supporting Information Supporting Information Get e-Alerts
Charged Polymers: From Polyelectrolyte Solutions to Polyelectrolyte Complexes (2021)

Coarse-grained molecular dynamics simulations, random phase approximation (RPA) approach, and scaling analysis are used to study static and dynamic properties of concentrated polyelectrolyte solutions of positively charged chains with the degree of polymerization N+ = 400 and their mixtures with negatively charged chains with degrees of polymerization N– varying between 10 and 400. Simulations show that both the effective chain Kuhn length and mean-square end-to-end distance of a chain decrease with increasing monomer concentration, pointing out screening of the electrostatic interactions by surrounding chains. The structure factor S(q) has a characteristic peak at intermediate wavenumbers q* which location moves toward smaller q values with decreasing monomer concentration. It is demonstrated that the plateau in S(q) at a small q is controlled by system compressibility and increases with increasing degree of polymerization of negatively charged chains. These results are in agreement with S(q) calculated in the framework of the RPA approach considering a solution of neutral chains as a reference system. In the framework of this approach, the location of the maximum in the scattering function at q* scales with monomer concentration as ρ–0.25. Analysis of the chain dynamics in the mixtures of oppositely charged chains shows that chain relaxation is a combination of constraint release and chain reptation processes. Constraint release is demonstrated to be the dominant mechanism in mixtures with negatively charged chains having intermediate degrees of polymerization. The degree of polymerization Ne between entanglements of the tube and super tube for charged systems is found to scale with concentration as Ne ∼ ρ–2 with corresponding packing numbers Pe = 18.45 ± 0.93. This is in contrast with mixtures of neutral chains, where in addition to Ne ∼ ρ–2 scaling, the degree of polymerization between entanglements of the super tube follows scaling Ne ∼ ρ–4/3 with packing number Pe = 6.64 ± 0.19.
Trimethylphosphine adduct of the zirconocene-benzyne complex: synthesis, reactions, and x-ray crystal structure (1986)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTrimethylphosphine adduct of the zirconocene-benzyne complex: synthesis, reactions, and x-ray crystal structureStephen L. Buchwald, Brett T. Watson, and John C. HuffmanCite this: J. Am. Chem. Soc. 1986, 108, 23, 7411–7413Publication Date (Print):November 1, 1986Publication History Published online1 May 2002Published inissue 1 November 1986https://pubs.acs.org/doi/10.1021/ja00283a048https://doi.org/10.1021/ja00283a048research-articleACS PublicationsRequest reuse permissionsArticle Views1407Altmetric-Citations158LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Designing an Online Infrastructure for Collecting AI Data From People With Disabilities (2021)

AI technology offers opportunities to expand virtual and physical access for people with disabilities. However, an important part of bringing these opportunities to fruition is ensuring that upcoming AI technology works well for people with a wide range of abilities. In this paper, we identify the lack of data from disabled populations as one of the challenges to training and benchmarking fair and inclusive AI systems. As a potential solution, we envision an online infrastructure that can enable large-scale, remote data contributions from disability communities. We investigate the motivations, concerns, and challenges that people with disabilities might experience when asked to collect and upload various forms of AI-relevant data through a semi-structured interview and an online survey that simulated a data contribution process by collecting example data files through an online portal. Based on our findings, we outline design guidelines for developers creating online infrastructures for gathering data from people with disabilities.