gebhart/patrepeval huggingface dataset:
Evaluation of enhanced manipulability in computer-aided teleoperation using a simulator (1991)

Fundamental data concerning the partitioning of functions between human operators and computers in teleoperation systems are presented in this paper. These data were obtained experimentally using a simulator. The simulator was made up of three components: a hypothetical robot manipulator capable of moving in a two-dimensional plane; an aiding device; and input devices necessary in the manual mode of teleoperation. The aiding device can substitute for a human operator for a while by operating the robot hand. It is demonstrated that the aiding device is very useful, especially in cases where the human operator is inexperienced or where the task is too difficult to do, for example, when the number of degrees of freedom of the manipulator's motion is high.
<title>Probabilistic multichannel optical flow analysis based on a multipurpose visual representation of image sequences</title> (1999)

Directional filters are not normally used as pre-filters for optical flow estimation because orientation selectivity tends to increase the aperture problem. Despite this fact, here we apply a subband decomposition using directional spatio-temporal filters at different resolution to discriminate multiple motions at the same location. We first obtain multiple estimates of the velocity by applying the classic gradient constraint to the output of each filter. Spatio-temporal gradients of GD2 channel response are easily obtained as linear combinations of the set of 10 separable GD3 channel responses, which constitutes a multipurpose scheme for visual representation of image sequences. Then, we obtain an overdetermined linear system by imposing local constant velocity. This system is solved by least-squares yielding an estimate of the velocity and its covariance matrix. After segmenting the resulting 6 X 3 velocity estimates we combine them using Bayesian probability rules. Segmentation maintains the ability to represent multiple motions, while the combination of estimates reduces the aperture problem. Results for synthetic and real sequences are highly satisfactory. Mean errors in complex standard sequences are below those provided by most published methods.
Simulation of electric machinery and power electronics interfacing using MATLAB/SIMULINK (2000)

This paper introduces power electronic and electric machines toolboxes based on the MATLAB/SIMULINK simulation package. Simulation components include DC-DC converters, power-factor-correction rectifiers, field-oriented and direct torque control methods for electric drives, induction machines, DC machines, synchronous machines, and more complete systems. Switching and averaged power electronic models are included, as well as dynamic and steady-state machine models. The toolboxes make possible the straightforward construction and simulation of complex dynamic systems involving power electronic components and machines.
Oxazoles in organic chemistry. 2. Application to the synthesis of benzylisoquinoline alkaloids (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOxazoles in organic chemistry. 2. Application to the synthesis of benzylisoquinoline alkaloidsAlan P. Kozikowski and Anthony AmesCite this: J. Org. Chem. 1980, 45, 12, 2548–2550Publication Date (Print):June 1, 1980Publication History Published online1 May 2002Published inissue 1 June 1980https://pubs.acs.org/doi/10.1021/jo01300a070https://doi.org/10.1021/jo01300a070research-articleACS PublicationsRequest reuse permissionsArticle Views246Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Hybrid broadcast and OTT delivery for terrestrial and mobile TV services (2014)

The service layer of LTE Broadcast is designed to broadcast formats that are commonly used in Over-The-Top Video Streaming, in particular DASH-formats. Whereas the initial deployments may focus on broadcast only modes, the design of using and combining OTT formats with broadcast distributions enables new opportunities and services in terms of combining broadcast distribution with OTT video services. These new features are discussed and progressed in 3GPP MBMS and ATSC3.0 in order provide the ability to distribute TV-centric content efficiently to a wide variety of devices including mobile phones, tablets and in-car receivers. This design enables a new use cases such as hybrid delivery, broadcast coverage extensions or MBMS On-Demand. The document provides insights into the architectures and technical details as defined in 3GPP. It will also provide examples on how LTE Broadcast service layer can be used in order to fulfill advanced and innovative use cases as discussed above. The final presentation will be supported by selected simulation results in order to show the benefits of the approach.
Development of Opioid Receptor Ligands (2006)

This chapter contains sections titled: Introduction Pharmacology Related to the Classic Opioid Receptors. Alkaloids from the Latex of Papaver somniferum Initiate Research Morphine: The Prototype Opioid Ligand Initial Studies of Morphine Analogues Structure–Activity Relationships of Morphine Derivatives Synthetic Analogues of Thebaine Further Define Morphinan SAR Compounds of the Morphinan Skeleton Produce New Agents Further Reduction of the Morphinan Skeleton Produced the Benzomorphans Another Simplified Version of Morphine Creates a New Class of Opioid Ligand A Breakthrough in the Structural Design of Opioid Ligands Discovery of the 4-Anilidopiperidines Phenylpropylamines: The Most Stripped-Down Opioids Still Related to Morphine The Use of Opioid Analgesics in Clinical Practice: Hope of the Future
Surface microfabrication of fused silica glass by UV laser irradiation (2004)

Surface micro-structuring of fused silica glass plates was performed by single-shot irradiation with a single-mode laser beam from a diode-pumped solid state UV laser at 355 nm. Well-defined micropattern without debris and microcrack formations around the etched area was fabricated by laser ablation with a focused laser-beam in the ambient air. The time-resolved optical emission spectra of plume were measured to elucidate the ablation behavior of silica glass induced by nanosecond-pulsed laser irradiation at 355 nm where absorption of silica glass is negligibly small. This method is suitable for rapid prototyping of surface microstructuing without a clean room environment.
Microblaze-based parallel implementations of elliptic curve scalar multiplication over <i>F<SUB align="right">p</i> on FPGA (2020)

This paper presents flexible software/hardware parallel architectures for embedded elliptic curve cryptosystem (ECC) on FPGA as multi-processor system on programmable circuit (MPSoPC) design. The implementations perform elliptic curve scalar multiplication (ECSM) over arbitrary prime fields (Fp) using montgomery power ladder (MPL) algorithm and Chudnovsky projective system. Our aim is to achieve the best trade-off between flexibility, area and speed. In fact, the integration of multi Microblaze processors allows not only the flexibility of the overall system but also the exploitation of the parallelism in ECSM computation with several degrees. At the low abstraction level, the critical finite field operation which is Montgomery modular multiplication (MMM) is implemented in hardware Accelerator MMM (AccMMM) core based on the modified high radix-r (r = 232) MMM algorithm. The proposed architectures have been implemented in Xilinx Virtex-5 FPGA. The execution times for performing 256-bit and 521-bit ECSM are 19.98 ms and 81.42 ms, respectively.
Left-to-right systolic and diastolic ventricular interactions are dependent on right ventricular volume (1997)

Three-compartment elastance modeling predicts that the magnitude of gain is solely dependent on the ratio of free wall and septal elastances. However, when nonlinearities in pressure-volume relationships are considered, the same model predicts that gain is load dependent. We therefore studied left-to-right ventricular interactions in the isolated cross-perfused canine heart preparation to determine whether, in fact, right ventricular volume modulates left-to-right ventricular interaction. We found that left-to-right systolic gain increased from 0.035 +/- 0.022 to 0.073 +/- 0.017 (P = 0.003) and left-to-right diastolic gain increased from 0.067 +/- 0.050 to 0.186 +/- 0.097 (P = 0.03) in response to increased right ventricular volume. This degree of volume dependency of gain is predicted by the three-compartment model when measured nonlinearities in time-varying elastance are taken into account. Future studies will need to account for changes in loading conditions when interpreting changes in systolic and diastolic interactions.
Molecular Bases of Protective Immune Responses against BotuIInum Neurotoxin AHow Antitoxin Antibodies Block Its Action (2007)

In studies from this laboratory, we localized the regions on the H chain of botulinum neurotoxin A (BoNT/A) that are recognized by anti-BoNT/A antibodies (Abs) and block the activity of the toxin in vivo. These Abs were obtained from cervical dystonia patients who had been treated with BoNT/A and had become unresponsive to the treatment, as well as blocking Abs raised in mouse, horse, and chicken. We also localized the regions involved in BoNT/A binding to mouse brain synaptosomes (snp). Comparison of spatial proximities in the three-dimensional structure of the Ab-binding regions and the snp binding showed that except for one, the Ab-binding regions either coincide or overlap with the snp regions. It should be folly expected that protective Abs when bound to the toxin at sites that coincide or overlap with snp binding would prevent the toxin from binding to nerve synapse and therefore block toxin entry into the neuron. Thus, analysis of the locations of the Ab-binding and the snp-binding regions provides a molecular rationale for the ability of protecting Abs to block BoNT/A action in vivo.
Chapter 13: Gallbladder and Sphincter of Oddi Disorders (2017)

Functional Gastrointestinal Disorders Disorders of Gut-Brain Interaction Fourth Edition VOLUMES I & II This page contains the DOI reference links for the online version of the Rome IV book, volumes I and II. If you have a Rome
Supplementary Data from Investigating the Contribution of Collagen to the Tumor Biomechanical Phenotype with Noninvasive Magnetic Resonance Elastography (2023)

&lt;p&gt;Contains Supplementary Methods and Table S1 and S2 which summarize the origin, characteristics, provenance and culture conditions of the cell lines used in this study&lt;/p&gt;
S4A-20 SESSION 4A: GENERALITIES IN CRANIOSYNOSTOSIS – PART I A CRITICAL CONTENT ANALYSIS OF SOCIAL MEDIA SUPPORT GROUPS FOR CRANIOSYNOSTOSIS: A VALUABLE TOOL FOR QUALITY IMPROVEMENT AND EDUCATION (2019)

Introduction: The parents and caregivers of patients with craniofacial disorders increasingly rely on social media for information and support, yet little is known in the surgical community about the information shared within these groups. We sought to characterize the content of posts in the largest Facebook support group for craniosynostosis to assess how providers can improve quality of outreach, education, and ultimately care for their patients. Methods: The Facebook group “Cranio Kids – Craniosynostosis Support” is the largest support group for craniosynostosis with over 15,000 members. We analyzed the last 1000 posts in this closed group as of January 1, 2019. Posts were categorized to identify the type of information shared within the group as well as how this information might be helpful to craniofacial surgeons to improve the care of their patients. Results: The 1000 examined posts were grouped into two broad categories: questions (n=517) and sharing of information (n=483). Several broad post themes were identified. Sub-groups within questions included questions about experience (n=213), questions seeking advice (n=197), questions regarding a diagnosis (n=41), surgeon inquiry (n=34), requesting support (n=20), requesting pictures (n=6), and others (n=6). Sharing of information consisted largely of medical updates (n=269), which were further characterized into pre-operative (n=58), peri-operative (n=5), and post-operative (n=206). In addition, photos (n=148) comprised a large sub-category within sharing of information, which were further grouped into pre-operative photos (n=77), post-operative photos (n=46), unknown photos (n=12), before/after photos (n=4), and other photos (n=9). Other sub-groups within sharing of information posts included sharing happy holiday wishes (n=22), non-medical social media updates (n=12), sharing fundraisers (n=4), sharing of news/media (n=3), sharing of products (n=3), and others (n=22). Interestingly, only 2 posts shared information regarding surgeons. Conclusion: This is the first study to characterize the content of social media support group posts. There is value to craniofacial surgeons in understanding the content of social media support group posts in order to identify general patient concerns, follow up on their outcomes, and identify areas for quality improvement.
Investigation of Input–Output Waveform Engineered Continuous Inverse Class F Power Amplifiers (2019)

An in-depth analysis of the continuous inverse Class F power amplifier (PA) accounting for nonlinear input and output active device properties is presented. The analyses show possible ways of exploiting input nonlinearity to improve and maintain PA performance in a broadband operation and propose a flexible source second-harmonic design space which reduces the input matching network (MN) design complexities. Such exploitation of input nonlinearity can also alleviate performance degradation due to dynamic knee behavior of a practical field-effect transistor (FET) in continuous inverse Class F PA operation. The analyses are validated with vector load-pull (VLP) measurements and utilized to implement a broadband PA design. High-drain efficiency (DE) over 75% and output power more than 38 dBm are achieved over 0.8-1.4 GHz at constant 3-dB gain compression.
Optical phase modulation using a refractive lenslet array and microelectromechanical deformable mirror (1998)

Microelectromechanical deformable mirrors (MEM-DMs) are attractive for optical phase modulation applications primarily because of their inherently low cost and low drive voltages. Two problems limiting widespread use of segmented piston MEM-DMs are low optical efficiency (fill factor) and undesired amplitude modulation resulting from interference with the static background structure. Using a lenslet array to focus the incident light onto only the reflective surface of the MEM-DM greatly improves the effective fill factor with a corresponding decrease in interference effects. A refractive lenslet array is used with a very low fill factor MEM-DM (∼7%) to comprise a correcting element that behaves like a 70 to 80% fill factor device. The MEM-DM has 128 active piston micromirror elements. Experiments employing the hybrid correcting element demonstrate single beam steering, dual beam steering, and optical aberration correction. A comprehensive model of the lenslet/MEM-DM geometry is developed. Measured data shows good agreement with model predictions. A thermal circuit model is developed to estimate optical power handling capability of the MEM-DM. A conservative estimate of maximum optical power for this particular MEM-DM is 4 W/element when operated in a helium ambient, suggesting that relatively high power laser control applications are feasible. © 1998 Society of Photo-Optical Instrumentation Engineers.
Crystal structure of (Z)-2,3-0-isopropylidene-D-erythro-4-pentenoseoxime,C8H13NO3 (1998)

Article Crystal structure of (Z)-2,3-0-isopropylidene-D-erythro-4-pentenoseoxime,C8H13NO3 was published on April 1, 1998 in the journal Zeitschrift für Kristallographie - New Crystal Structures (volume 213, issue 1-4).
Feasibility of Amylin Imaging in Pancreatic Islets with β-Amyloid Imaging Probes (2014)

Islet amyloid deposition composed of amylin aggregates is regarded as one of the hallmarks of type 2 diabetes mellitus (T2DM). For the diagnosis of T2DM, several nuclear medical imaging probes have been developed. However, there have been no reports regarding the development of imaging probes targeting amylin. In this report, we investigated the feasibility of amylin imaging using [(125)I]IPBF as one of the model compounds of β-amyloid (Aβ) imaging probes. In in vitro experiments, [(125)I]IPBF exhibited high binding affinity for amylin aggregates (Kd = 8.31 nM). Moreover, autoradiographic images showed that [(125)I]IPBF specifically bound to islet amyloid composed of amylin. These results suggest the potential application of Aβ imaging probes to amylin imaging. In addition, [(125)I]IPBF is one of the promising lead compounds for amylin imaging, and further structural optimization based on [(125)I]IPBF may lead to useful tracers for the in vivo imaging of islet amyloids in the pancreas.
Assessment of specific contribution of residual stress generated near surface anomalies in the high temperature fatigue life of a René 65 superalloy (2016)

Abstract This study evaluates the influence of residual stresses induced by the fabrication of surface anomalies on the fatigue crack growth in a nickel based superalloy. To separate the notch effect of the geometry from the residual stress field induced by fabrication of the surface flaws, two V‐type anomalies are considered: scratches and dents with equivalent morphology and size. A specially designed heat treatment has been used to reduce the magnitude of residual stresses around these anomalies in order to highlight their effects on the different stages of the crack propagation, under low cycle fatigue conditions at 400 °C. The crack initiation life is short for both anomalies but in the presence of compressive residual stresses, a decrease of the fatigue crack growth rate has been observed during the first stages of the crack propagation. Furthermore, the results showed that without residual stresses, scratches and dents exhibit the same behaviour. Thus, the residual stress field below surface anomalies is the main parameter controlling the fatigue life from surface anomalies.
Side-gated ultrathin-channel nanopore FET sensors (2016)

A side-gated, ultrathin-channel nanopore FET (SGNAFET) is proposed for fast and label-free DNA sequencing. The concept of the SGNAFET comprises the detection of changes in the channel current during DNA translocation through a nanopore and identifying the four types of nucleotides as a result of these changes. To achieve this goal, both p- and n-type SGNAFETs with a channel thicknesses of 2 or 4 nm were fabricated, and the stable transistor operation of both SGNAFETs in air, water, and a KCl buffer solution were confirmed. In addition, synchronized current changes were observed between the ionic current through the nanopore and the SGNAFET's drain current during DNA translocation through the nanopore.
392 A SELECTIVE ESTROGEN RECEPTOR BETA AGONIST MODULATES NEUROPATHIC AND INFLAMMATORY PAIN STATES (2007)

Background and aims. The effects of estrogens on pain perception remain quite controversial. Depending on the animal models, both beneficial and detrimental effects of non-selective estrogens have been reported in the literature. Further, the results of multiple human clinical trials examining the potential beneficial effects of estrogens in breast, bone, pelvic pain have been inconclusive as well. While the underlying mechanisms for these discrepancies are not understood, we believe they are likely to arise from the lack of selectivity of estrogens for their two cognate receptors, the nuclear hormone receptors ER alpha and ER beta. Results and conclusions. Using a proprietary functional cell-based platform technology (R-SAT®: Receptor Selection and Amplification Technology), non steroidal ER beta pharmacophores were identified. They define two classes of small molecule agonists, with low nanomolar affinity for ER beta and a high degree of selectivity (>100–1000-fold) versus ER alpha and other nuclear receptors. A prototype lead molecule, ERb-131, was evaluated in several pain animal models involving nerve injury or sensitization. ERb-131 reversed tactile allodynia caused by spinal nerve ligation (Chung model) and chemical insults. ERb-131 also alleviated tactile or thermal hyperalgesia in both acute and chronic inflammation models (capsaicin, CFA, formalin). Finally, ERb-131 did not influence the pain threshold of normal healthy animals. Thus, ER beta agonism is a critical effector in the mediation of broad anti-nociceptive states.
Polarization diversity with directional antennas for indoor environments (2003)

The aim of this paper is to find out the performance of a polarization diversity technique with a directional antenna for the indoor environment. The performance can be evaluated on the basis of the correlation coefficient and cumulative distribution function. Experiments were conducted at IMT-2000's frequency. A 3D ray-tracing model for indoor communications with antennas of arbitrary directivity and polarization is presented. The measurement and simulation results show that the polarization diversity with the directional dual polarized microstrip antenna is expected to be more efficiently used than conventional polarization and space diversity with the dipole antenna for indoor environments.