gebhart/patrepeval huggingface dataset:
Eddy Current Loss Minimization in Conducting Sleeves of High Speed Machine Rotors by Optimal Axial Segmentation and Copper Cladding (2007)

When a non-magnetic, high-strength metallic retaining sleeve offers advantages over a non-metallic (e.g. carbon fiber) one, it is possible to consider the application of a high conductivity shield coating on this sleeve to reduce the surface eddy current losses due to non-synchronous fields. One can start by using a Maxwell's equations based analytical model to screen for the optimal shield thickness and then employs a 2.5D FE method that accounts for periodic fields and finite rotor length including axial segmentation and/or copper cladding. These are quantified to help design a low loss rotor sleeve for a high speed SPM machine with fractional-slot concentrated armature winding. With this type of windings the sleeve losses can be significant due to its rich asynchronous harmonic armature reaction mmf content.
Accuracy and stability improvement of tomography video signatures (2010)

Video signature techniques based on tomography images address the problem of video identification. This method relies on temporal segmentation and sampling strategies to build and determine the unique elements that form the signature. In this paper an extension for these methods is presented; first an implementation for high contrast sub-sampling and up-sampling filters is used to increase tomography edge stability, then a robust temporal video segmentation system is used to replace the original method applied to determine shot changes more accurately, and finally a new feature extraction method, derived from the previously proposed sampling pattern, was implemented and tested, resulting in a highly distinctive set of signature elements. The video set for the test was recorded from live broadcast TV, using as queries 20 different commercials, with the objective of analyzing the audit proficiency of the signatures for new applications. The performance obtain over the version presented in [3] is significant with 99.58% of Recall and 99.35% of Precision prediction.
Rapid and accurate detection of novel coronavirus SARS-CoV-2 using CRISPR-Cas3 (2020)

Novel coronavirus SARS-CoV-2 outbreaks have rapidly spread to multiple countries, highlighting the urgent necessity for fast, sensitive, and specific diagnostic tools for virus surveillance. Here, the previously unknown collateral single-stranded DNA cleavage we observed with type I CRISPR-Cas3 highlights its potential for development as a Cas3-mediated rapid (within 40 min), low-cost, instrument-free detection method for SARS-CoV-2. This Cas3-based assay is comparable with Cas12- and real-time reverse-transcriptase PCR-based assays in its speed and sensitivity, but offers greater specificity for single-base-pair discrimination while negating the need for highly trained operators. These findings support the use of CRISPR diagnostics for point-of-care testing in patients with suspected SARS-CoV-2 infections.
The role of oxide defect chemistry in the drude and plasmonic response of optical fiber-based sensing layers for high-temperature gas sensing (2021)

Many systems within the energy sector necessitate high-temperature or chemically harsh conditions (e.g., solid oxide fuel cells, power plant boiler systems, post-combustion facilities). Significant economic and technological value can be added through the integration of <i>in-situ</i> sensor technology; unfortunately, harsh environments pose a major challenge to traditional sensor materials. Optical fiber-based sensors provide a robust solution to this problem and offer capability for spatially distributed sensing. Silica fiber, with cladding removed and coated with bare or metallic nanoparticle incorporated sensing layers, exhibits stability up to 800-900&deg;C under a wide range of chemical environments. As sensing layers, complex perovskites oxides - studied extensively as anode and cathode materials within the solid oxide fuel cell (SOFC) community – provide ideal tunability, stability, and defect-dependent optical properties for high-temperature gas-sensing applications. Modeled defect chemistry kinetics are presented in the context of experimental high-temperature (600-800&deg;C) optical gas sensor data at visible and NIR wavelengths, both on planar substrates and on optical fiber. Doped SrTiO<sub>3</sub> is highlighted as a model sensing material, due to strong Drude response under chemically reducing conditions, and due to its well-documented material / chemical properties. Equilibrium calculations are performed for ionic and electronic motion within thin films on fiber – using a ray-based approach for guided optical modes.
Epstein–Barr Virus-Associated Lymphoma in a Child Undergoing an Autologous Stem Cell Rescue (2002)

Epstein-Barr virus-associated lymphoproliferative disease (EBV-LPD) is a serious disorder seen in various states of immunodeficiency, often with a fatal outcome. In this article, a patient with EBV-lymphoma after autologous stem cell rescue for treatment of a nonhematologic solid tumor is described. The child, a 4-year-old boy, had unilateral retinoblastoma with metastatic spread to the central nervous system. He had previously received both local tumor bed and craniospinal radiation therapy together with intensive myeloablative alkylator chemotherapy before autologous stem cell rescue. Histologically confirmed lymphoma with evidence of active EBV proliferation developed within cervical lymph nodes 3 weeks after his first autologous stem cell rescue. A complete clinical remission of the lymphadenopathy was obtained after infusions of rituximab (an anti-CD20 monoclonal antibody), acyclovir, and high-titer anticytomegalovirus immunoglobulin. The patient died approximately 6 months later of persistent and progressive retinoblastoma without any clinical evidence of lymphoma. It is concluded that EBV-LPD should be included in the differential diagnosis in patients in whom lymphadenopathy develops after autologous stem cell rescue.
Compatibility of FM hybrid in-band on-channel (IBOC) system for digital audio broadcasting (1997)

A robust in-band on-channel (IBOC) digital audio broadcast (DAB) system for improved performance over existing FM broadcasting is under development by Westinghouse for USA Digital Radio. Both the analog FM and the DAB signals are transmitted simultaneously in the FM hybrid IBOC system. Broadcasters can simultaneously transmit both analog and digital signals within the allocated channel mask, allowing full compatibility with existing analog receivers. It is shown here that the solution is tolerant of interference from adjacent channels, or interference from the co-channel analog transmission, even in a multiple station, strong-signal urban market. Although the primary focus of this paper is to discuss the compatibility issues between the existing FM and the DAB signals, the paper also briefly describes spectral occupancy, power ratios, modulation formats, and coding, as well as the introduction of frequency and time diversity.
Automatic detection system for multiple region of interest registration to account for posture changes in head and neck radiotherapy (2014)

Despite immobilization of head and neck (H and N) cancer patients, considerable posture changes occur over the course of radiotherapy (RT). To account for the posture changes, we previously implemented a multiple regions of interest (mROIs) registration system tailored to the H and N region for image-guided RT correction strategies. This paper is focused on the automatic segmentation of the ROIs in the H and N region. We developed a fast and robust automatic detection system suitable for an online image-guided application and quantified its performance. The system was developed to segment nine high contrast structures from the planning CT including cervical vertebrae, mandible, hyoid, manubrium of sternum, larynx and occipital bone. It generates nine 3D rectangular-shaped ROIs and informs the user in case of ambiguities. Two observers evaluated the robustness of the segmentation on 188 H and N cancer patients. Bland-Altman analysis was applied to a sub-group of 50 patients to compare the registration results using only the automatically generated ROIs and those manually set by two independent experts. Finally the time performance and workload were evaluated. Automatic detection of individual anatomical ROIs had a success rate of 97%/53% with/without user notifications respectively. Following the notifications, for 38% of the patients one or more structures were manually adjusted. The processing time was on average 5 s. The limits of agreement between the local registrations of manually and automatically set ROIs was comprised between ±1.4 mm, except for the manubrium of sternum (-1.71 mm and 1.67 mm), and were similar to the limits agreement between the two experts. The workload to place the nine ROIs was reduced from 141 s (±20 s) by the manual procedure to 59 s (±17 s) using the automatic method. An efficient detection system to segment multiple ROIs was developed for Cone-Beam CT image-guided applications in the H and N region and is clinically implemented in our department.
Complex 3D shaped particle fabrication via inertial flow deformation and UV polymerization (2013)

At finite Reynolds number, sequences of structures (i.e. pillars or columns) in a channel create a combined secondary flow enabling the precise control of flow cross sectional shape. Using an inertial flow deformation control scheme and previously reported UV polymerization techniques used to fabricate 2D extruded particles, we present a novel fabrication process to create complex 3D%shaped particles. A shaped stream of polymer%precursor and photoinitiator is exposed to orthogonal masked UV light, creating 3D shapes consisting of the extrusion of two 2D shapes. We present the results from numerical and experimental studies on the flow deformation physics and possible shapes achievable.
Small interference RNA targeting heat‐shock protein 27 inhibits the growth of prostatic cell lines and induces apoptosis via caspase‐3 activation in vitro (2006)

These findings illustrate the potential utility of Hsp27-silencing therapy and highlight Hsp27 siRNA strategies as a novel and highly effective tool, with the potential for future targeted therapy in enhancing the efficacy of chemotherapy in advanced prostate cancer.
Development of a Scalable Method for Manufacturing the Central Core of CD73 Inhibitor AB680 (2020)

AB680 is a highly potent CD73 small molecule inhibitor discovered and developed by Arcus Biosciences, currently in clinical trials for the treatment of pancreatic cancer. Here, we report the development of a scalable and practical method for the manufacturing of the azaindazole central core. This synthesis features an N-oxide formation followed by an α-chlorination with POCl3 leading to the formation of 4,6-dichloro-1H-pyrazolo[3,4-b]pyridine 1 in high yield and 99.5% UV purity. This method was successfully performed on multikilogram scale to support the synthesis of AB680.
Statins reduce the risk of liver decompensation and death in chronic viral hepatitis: a propensity score weighted landmark analysis (2017)

Patients with chronic viral hepatitis who used statins have a reduced risk of liver decompensation and death compared to non-users in this propensity score weighted landmark analysis.
Association between golli-MBP and schizophrenia in the Jewish Ashkenazi population: are regulatory regions involved? (2009)

Multiple studies have reported oligodendrocyte and myelin abnormalities, as well as dysregulation of their related genes, in brains of schizophrenia patients. One of these genes is the myelin-basic-protein (MBP) gene, which encodes two families of proteins: classic-MBPs and golli-MBPs. While the classic-MBPs are predominantly located in the myelin sheaths of the nervous system, the golli proteins are more widely expressed and are found in both the immune and the nervous systems. In the present study we performed a case-control association analysis of golli-MBP in two separate Jewish Ashkenazi cohorts (cohort I: 120 patients, 236 controls; cohort II: 379 patients, 380 controls). In addition we performed an expression analysis of golli-MBP mRNA in post-mortem dorsolateral prefrontal cortex samples of schizophrenia patients, and matched controls. In the first cohort we observed association between six (out of 26 genotyped) single nucleotide polymorphisms (SNPs) and the disease (p<0.05). Of these, three are from one linkage disequilibrium (LD) block which contains a CTCF binding region. Haplotype analysis revealed significant 'risk'/'protective' haplotypes (strongest p=0.005, each) for schizophrenia. The three SNPs (rs12458282, rs2008323, rs721286) were then genotyped in the second cohort. The combined results showed strong effects, both in the single marker and in haplotype analyses (strongest OR 1.77, p=0.0005; OR 1.61, p=0.00001, respectively). Sequencing the CTCF binding region revealed three SNPs in complete LD with the associated haplotypes, located in close proximity to the CTCF binding site. Expression analysis found no significant differences in golli-MBP mRNA levels. These findings suggest that golli-MBP is a possible susceptibility gene for schizophrenia.
PANA Mobility Optimizations (2005)

This specification describes PANA optimizations for handling mobility.
Proposed optimizations aim reducing protocol latency and signaling
associated with PANA-based network access AAA.
Numerical analysis of a novel MTJ stack for high readability and writability (2011)

A novel MTJ stack employing a bidirectional switching mechanism has been proposed. By using a pulsed bidirection current, an MTJ with a SAF free layer and AP fixed layers can be switched through a metastable ferromagnetic state. Numerical simulations suggest high readability (like single barrier structures) and writability (like double barrier structures) of the proposed device.
Tuned Cationic Dendronized Polymer: Molecular Scavenger for Rheumatoid Arthritis Treatment (2019)

Cell-free deoxyribonucleic acid (cfDNA) released from either dead or damaged cells serves as a key autoantigen in rheumatoid arthritis (RA). They can be recognized by nucleic acid (NA) sensors such as the toll-like receptor (TLR), leading to activation of the innate immune system and chronic inflammation. Developed here is a cationic molecular scavenger, by screening cationic dendronized polymers, which eliminates cfDNA and inhibits TLR recognition and nucleic-acid-induced inflammation. The structure-property study demonstrates that toxicity, NA binding capacity, and biodistribution could be balanced to achieve maximum therapeutic effect by exquisite control of the molecular structure. In addition, the optimized cationic polymer effectively inhibited joint swelling, synovial hyperplasia, and bone destruction in collagen-induced arthritis (CIA) rat models. The results offer support for synthetic polymers offering new paradigm in autoimmune disease treatment.
Patterned Nafion membrane for proton exchange membrane fuel cell with ultra-low Pt catalyst loading (2015)

To reduce the cost of proton exchange membrane fuel cell (PEMFC), one approach is to minimize the amount of platinum. The use of physical vapor deposition process for the synthesis of efficient catalysts and for the development of fuel cells based on thin catalytic layers [1] has already significantly reduced the amount of platinum catalyst [2]. However, when the platinum catalyst is directly deposited on the membrane by magnetron sputtering (without the use of catalytic inks), the power density (in Wcm-2) delivered by the fuel cell is currently limited. Such fuel cell based on CCM architecture (catalyst coated membrane) with a Pt loading of 20 μgPtcm-2 is able to deliver up to 25 kilowatts per gram of platinum, while the power density is 0.5 Wcm-2.
To improve the power density delivered by CCM fuel cell, the GREMI laboratory and the CEA aim to increase the membrane surface by using pulsed laser micromachining before the physical vapor deposition of Pt catalyst. A femtoseconde laser is used to create craters, dumps and ripples on the surface of stainless steel molds. These are then pressed against a Nafion membrane to print the negative of these patterns on one of its face. By using such process, micrometer and sub-micron designs appear on the surface of the Nafion membrane. The patterned membranes are then covered by Pt catalytic nanoclusters and tested in H2/O2 PEMFC. Their electrical characteristics are compared to fuel cell based on un-patterned membrane. Patterned membranes lead to an increase of the delivered power density. The most efficient fuel cell delivers 0.73 mWcm-2 with a Pt loading of 25 μgPtcm-2 on the cathode side. This improvement appears to come from an increase of the catalytic activity and of the membrane conductivity.
REFERENCES
[1] Pascal Brault, Amael Caillard, Steve Baranton, Mathieu Mougenot, St¦phane Cuynet, and Christophe Coutanceau, ChemSusChem 2013 6, 1168–1171 
[2] M. Cavarroc, A. Ennadjaoui, M. Mougenot, P. Brault, R. Escalier, Y. Tessier, J. Durand, S. Roualdes, T. Sauvage, C. Coutanceau, Electrochemistry Communications 2009 11 859–861
OPTICAL PROPERTIES INDIUM OXIDE AND INDIUM TIN OXIDE FILMS PREPARED BY SPUTTERING (1996)

Thin films of indium oxide and indium tin oxide have been prepared by d.c. magnetron sputtering onto the fused silica substrates kept at 90, 200 and . In order to elucidate the optical absorption process in low energy region below 3 eV, we have analyzed the absorption coefficients obtained from reflectance and transmittance measurements for these films based on the Lucovsky model. It has been found for the first time that a defect center in the band gap is located at 0.8~1.4 eV below the Fermi level in all films and arises from oxygen vacancies in their films. The optical absorption in low energy region is explained to be dominated by the transition of electrons trapped at the positively charged (+2e) oxygen vacancies with s-like nature to the conduction band formed from the 5s-orbit in indium atoms.
Exploiting Water Vapor for Security in Terahertz Wireless Links (2022)

We experimentally demonstrate the terahertz wireless channel fading due to atmospheric water vapor attenuation and distortion, and propose a protocol of utilizing this effect for physical-layer security.
Broadband Terahertz Polarizers with Ideal Performance Based on Aligned Carbon Nanotube Stacks (2012)

We demonstrate a terahertz polarizer built with stacks of aligned single-walled carbon nanotubes (SWCNTs) exhibiting ideal broadband terahertz properties: 99.9% degree of polarization and extinction ratios of 10–3 (or 30 dB) from ∼0.4 to 2.2 THz. Compared to structurally tuned and fragile wire-grid systems, the performance in these polarizers is driven by the inherent anistropic absorption of SWCNTs that enables a physically robust structure. Supported by a scalable dry contact-transfer approach, these SWCNT-based polarizers are ideal for emerging terahertz applications.
The photobiology of the gilvocarcins. Total synthesis of defucogilvocarcin V and a related photoactive vinyl phenol (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe photobiology of the gilvocarcins. Total synthesis of defucogilvocarcin V and a related photoactive vinyl phenolLawrence R. McGee and Pat N. ConfaloneCite this: J. Org. Chem. 1988, 53, 16, 3695–3701Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/jo00251a008https://doi.org/10.1021/jo00251a008research-articleACS PublicationsRequest reuse permissionsArticle Views315Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Plasma treatment and its prospective application to polymer light-emitting diodes fabricated by ink-jet printing method (2005)

The influence of CF4 plasma treatment of indium-tin-oxide (ITO) and polyimide (PI) on the patterning of ink-jet printed polymer is presented. Not much difference between the as-received ITO and PI surface energies was found, but a significant difference in surface energies between ITO and PI after CF4 plasma treatment was noted. It is expected that precise patterning can be achieved by using the difference in surface energies between the inside of the pixel and its surroundings. Also the effects of CF4 plasma treatment of ITO have been studied on the performance of polymer light-emitting diodes (PLEDs). X-ray photoelectron spectroscopy revealed that CF4 plasma treatment led to a decrease in the surface content of carbon contaminants and an increase in the surface content of fluorine, which in turn enhance the performance of PLEDs.
Electromagnetic scattering from long nanowires (2007)

To study the electromagnetic properties of nanowires composed of various materials at infrared and optical frequencies, the dispersive nature of the material must be incorporated into the modeling approach. In the paper, the use of the complex dielectric function and mathematical models for the dispersive properties of the material, specifically in this case for Gallium Phosphide (GaP) material is discussed. Using these material models, large aspect ratio nanowires ( "long nanowires ") are examined. Using analytical techniques, the intensity of electric fields inside the nanowire are studied for normal incidence. Computational methods such as the finite-difference time-domain (FDTD) technique are also be used to study the behavior of finite length nanowires.
Cherenkov imaging for Total Skin Electron Therapy (TSET) (2018)

Total Skin Electron Therapy (TSET) utilizes high-energy electrons to treat cancers on the entire body surface. The otherwise invisible radiation beam can be observed via the optical Cherenkov photons emitted from interaction between the high-energy electron beam and tissue. Using a specialized camera-system, the Cherenkov emission can thus be used to evaluate the dose uniformity on the surface of the patient in real-time. Each patient was also monitored during TSET via in-vivo detectors (IVD) in nine locations. Patients undergoing TSET in various conditions (whole body and half body) were imaged and analyzed, and the viability of the system to provide clinical feedback was established.