gebhart/patrepeval huggingface dataset:
Orientation Dependence of Si1-xCx:P Growth and the Impact on FinFET Structures (2013)

The shift of device design to more complex structures with multiple crystallographic orientations has significantly complicated the incorporation of mobility enhancing stressors. The growth rate, composition and crystalline perfection of these stressors is dependent on the crystal orientation and is therefore of significant importance. For embedded source-drain and FinFET devices there are multiple crystallographic orientations present during the epitaxial stressor growth process. The compositional, growth rate and crystal quality dependence of Si1-xCx:P blanket epitaxial growth results on (001), (011), and (111) oriented Si substrates will be discussed and how they relate to the processing of FinFET device structures.
FGLP: A Federated Fine-Grained Location Prediction System for Mobile Users (2021)

Fine-grained location prediction on smart phones can be used to improve app/system performance. Application scenarios include video quality adaptation as a function of the 5G network quality at predicted user locations, and augmented reality apps that speed up content rendering based on predicted user locations. Such use cases require prediction error in the same range as the GPS error, and no existing works on location prediction can achieve this level of accuracy. We present a system for fine-grained location prediction (FGLP) of mobile users, based on GPS traces collected on the phones. FGLP has two components: a federated learning framework and a prediction model. The framework runs on the phones of the users and also on a server that coordinates learning from all users in the system. FGLP represents the user location data as relative points in an abstract 2D space, which enables learning across different physical spaces. The model merges Bidirectional Long Short-Term Memory (BiLSTM) and Convolutional Neural Networks (CNN), where BiLSTM learns the speed and direction of the mobile users, and CNN learns information such as user movement preferences. FGLP uses federated learning to protect user privacy and reduce bandwidth consumption. Our experimental results, using a dataset with over 600,000 users, demonstrate that FGLP outperforms baseline models in terms of prediction accuracy. We also demonstrate that FGLP works well in conjunction with transfer learning, which enables model reusability. Finally, benchmark results on several types of Android phones demonstrate FGLP's feasibility in real life.
The LINPACK Benchmark: past, present and future (2003)

Abstract This paper describes the LINPACK Benchmark and some of its variations commonly used to assess the performance of computer systems. Aside from the LINPACK Benchmark suite, the TOP500 and the HPL codes are presented. The latter is frequently used to obtained results for TOP500 submissions. Information is also given on how to interpret the results of the benchmark and how the results fit into the performance evaluation process. Copyright © 2003 John Wiley &amp; Sons, Ltd.
Anti-proliferative and antitumoral activities of a functionalized dextran (CMDBJ) on the 1205 L-U human tumor melanoma cells. (2002)

Carboxy methyl dextran benzylamide jorge (CMDBJ) is a derivatized dextran prepared from native dextran after random carboxymethylation of hydroxyl groups on D-glucose units (CM) and consecutive conversion of some carboxylate groups to benzylamide structures (B). This polymer exhibits an inhibitory action upon the proliferation of 1205 L-U human melanoma cells. At low concentrations, this compound exerts a cytostatic effect whereas, at higher concentrations, a cytotoxicity appears within 24 hours of treatment. The 1205 L-U cell line forms subcutaneous angiogenic tumors in athymic mice and, after several weeks, spontaneously forms micrometastasis in the lungs. We demonstrated that the CMDBJ treatment of animals not only reduces the rapid growth of primary tumors but also induces tumor regression and tumor necrosis. Moreover, CMDBJ treatment blocks the appearance of lung metastasis. Pleiotrophin (PTN), heparin-binding angiogenic growth factor, is secreted by 1205 L-U cells and breast tumor MDA-MB 231 cells. CMDBJ, as an inhibitor of heparin-binding growth factor activities, suppresses the mitogenic activity of conditioned media from 1205 L-U and MDA-MB 231 on endothelial HUVEC cells. We conclude that CMDBJ can inhibit the in vitro cell proliferation of 1205 L-U cells and 1205 L-U tumor development in athymic mice and that PTN secreted by these cells could be involved in this inhibition.
Optimization Techniques to Improve Inference Performance of a Forward\n Propagating Neural Network on an FPGA (2020)

This paper describes an optimized implementation of a Forward Propagating\nClassification Neural Network which has been previously trained. The\nimplementation described highlights a novel means of using Python scripts to\ngenerate a Verilog hardware implementation. The characteristics of this\nimplementation include optimizations to scale input data, use selected addends\ninstead of multiplication functions, hardware friendly activation functions and\nsimplified output selection. Inference performance comparison of a 28x28 pixel\n'hand-written' recognition NN between a software implementation on an Intel i7\nvs a Xilinx FPGA will be detailed.\n
Modeling of piezoelectric coupling coefficients of soft ferroelectrets for energy harvesting (2019)

Recently, Fluoroethylenepropylene (FEP) tubes have been thermally fused to form ferroelectrets with a parallel-tunnel structure with well-defined air gaps thereby improving their applicability for energy harvesting applications. These structures exhibit mechanical and electric properties, mostly depending on their geometry, which result in structure-specific longitudinal and transversal piezoelectric coupling coefficients (d <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">33</sub> and d <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">31</sub> ). This work presents a finite element model able to describe the mechanical-to-electrical coupling of FEP parallel tunnel structures. The focus of the presented paper, however, lies singularly on the coefficient d <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">33</sub> , neglecting the transversal coupling coefficient d <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">31</sub> . The coupling coefficient d <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">33</sub> is calculated in three main steps. First, the induced charge on the electrode's surface for the unloaded state is determined. Second, the deformation of the structure due to an external force applied in thickness direction is computed. Third, the modified shape is used to determine the electrode's charge variation. The model correctly predicts the experimental values for the Young's moduli in the range of 0.6 MPa to 0.9 MPa, within 10 %. The piezoelectric coefficient d <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">33</sub> is predicted for two internal charge densities, namely 3 x 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-4</sup> C/m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> and 5 x 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-4</sup> C/m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . The respective d <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">33</sub> coefficients are 110 and 240 pC/N. This is in excellent agreement with measured values of 120 and 180 pC/N, respectively. The results prove the finite element model to be suitable to calculate the piezoelectric coupling coefficients for different types of geometries.
A Detailed Router for Field-Programmable Gate (1992)

This paper describes a new kind of detailed routing algorithm that has been designed specifically for field-program- mable gate arrays (FPGA's). The algorithm is unique in that it approaches this problem in a general way, allowing it to be used over a wide range of different FPGA routing architee- tures. The detailed routing of FPGA's is a new problem and can be more difficult than classic detailed routing because the wiring segments that are available for routing are Preplaced and can only be ~onnected together in specified patterns. In some FPGA's, the routing architecture places exacting limita- tions on the routing choices for any connection, and in such cases there will routing channels in the FPGA where overlap- ping routing alternatives of two or more connections create
Catalytic Asymmetric Synthesis of a Tertiary Benzylic Carbon Center via Phenol-Directed Alkene Hydrogenation (2011)

An expeditious synthetic approach to chiral phenol 1, a key building block in the preparation of a series of drug candidates, is reported. The strategy includes a cost-effective and readily scalable route to cyclopentanone 3 from isobutyronitrile (10). The sterically hindered and enolizable ketone 3 was subsequently employed in a challenging Grignard addition mediated by LaCl(3)·2LiCl. A novel preparation of the lanthanide reagent required for this transformation is described. To complete the process, a highly enantioselective hydrogenation step afforded the target (1). The importance of the phenol group to the success of this asymmetric transformation is discussed.
OAM for Service Programming with Segment Routing (2019)

This document defines the Operations, Administrations and Maintenance
(OAM) for service programming in SR-enabled MPLS and IP networks.
Performance of Data Transmission in Wireless Power Transfer with Coil Displacements (2014)

This letter investigates the relationship between antenna position and data communication performance in a magnetic resonance wireless power transfer (MRWPT) system. In MRWPT information such as the types of equipments, the required amount of electrical power, or the timing of power transfer should be exchanged. It is assumed here that power transfer coils in the MRWPT system are employed as antennas for data communication. The frequency characteristics of the antennas change due to coil displacements. The power transfer coils are modeled as a band pass filter (BPF) and the frequency characteristics of the filter are presented in this letter. The characteristics of the filter are derived through circuit simulation and resulting data communication performance is evaluated. Numerical results obtained through computer simulation show that the bit error late (BER) performance can be improved by controlling the center frequency of the communication link.
Ground Fault Detection Method for Variable Speed Drives (2021)

The use of variable speed drives made essential the presence of power electronic in electrical systems. The ac to dc and dc to ac conversions, thanks to rectifiers and inverters cause difficulties in the ground fault detection. In this article, a new method to detect ground faults in variable speed drives is presented. It is based on the analysis of the terminal voltage signal of a grounding resistor connected between the neutral at the secondary of the main power transformer and ground. Attending to the waveform, the ground fault can be detected on the ac grid side, dc positive or negative terminals, or ac inverter side. To verify the method, numerous simulations and experimental tests in a 140-kW power converter were carried out achieving satisfactory results.
Reliable multiplex sequencing with rare index mis-assignment on DNB-based NGS platform (2019)

Single indexing with DNB technology provides a simple but effective method for sensitive genetic assays with large sample numbers.
Polarization-independent optical ring resonators on silicon-on-insulator (2004)

Because of their compact size, ring resonators can be a cost effective solution for many Dense Wavelength Division Multiplexing (DWDM) components, as well as many low cost applications such as part of optical sensor circuits, or low cost optical signal processing. Modulators, filters, add-drop multiplexers, and switches are all components that can be realised with a ring resonator. Their potentially large Free Spectral Range (FSR), finesse, and quality factor, together with the potential for low cost fabrication, make them a viable alternative to many current DWDM devices. However, for such devices to be commercially viable, they need to be insensitive to the polarisation state of the input signal. The results obtained herein show that a single input/output optical racetrack resonator has been fabricated so that the minima in the resonance spectra align to better than 1pm. The rings also exhibit relatively low loss with measured Q-factors of approximately 90,000 and finesse values of 12.
Osseous and vascular anatomical variations within the C1–C2 complex: a radiographical study using computed tomography angiography (2008)

The size, location and path of the VA cannot be precisely predicted by the appearance of osseous structures such as the transverse foramina and/or the VA groove. CTA provides additional information regarding the atlanto-axial complex, and should be considered as a useful adjunct in the preoperative evaluation of select patients.
Tunable quasi-phase matching using dynamic ferroelectric domain gratings induced by photorefractive space-charge fields (1994)

We demonstrate a method of dynamic, tunable quasi-phase matched second-harmonic generation using optically induced polarization gratings with periods equal to twice the coherence length. These gratings increase the peak second-harmonic conversion efficiency by a factor of 17 above a poled strontium barium niobate crystal, to 0.01% for fundamental beam intensities of 0.8 MW cm−2. We generate quasi-phase matching spectral response peaks as narrow as 0.175 nm and tailor the response by writing an ensemble of gratings in the same volume, each of which enhances the second-harmonic generation at a predetermined wavelength.
Data from NK Cells Mediate Synergistic Antitumor Effects of Combined Inhibition of HDAC6 and BET in a SCLC Preclinical Model (2023)

&lt;div&gt;Abstract&lt;p&gt;Small-cell lung cancer (SCLC) has the highest malignancy among all lung cancers, exhibiting aggressive growth and early metastasis to distant sites. For 30 years, treatment options for SCLC have been limited to chemotherapy, warranting the need for more effective treatments. Frequent inactivation of TP53 and RB1 as well as histone dysmodifications in SCLC suggest that transcriptional and epigenetic regulations play a major role in SCLC disease evolution. Here we performed a synthetic lethal screen using the BET inhibitor JQ1 and an shRNA library targeting 550 epigenetic genes in treatment-refractory SCLC xenograft models and identified HDAC6 as a synthetic lethal target in combination with JQ1. Combined treatment of human and mouse SCLC cell line–derived xenograft tumors with the HDAC6 inhibitor ricolinostat (ACY-1215) and JQ1 demonstrated significant inhibition of tumor growth; this effect was abolished upon depletion of NK cells, suggesting that these innate immune lymphoid cells play a role in SCLC tumor treatment response. Collectively, these findings suggest a potential new treatment for recurrent SCLC.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Significance:&lt;/b&gt; These findings identify a novel therapeutic strategy for SCLC using a combination of HDAC6 and BET inhibitors. &lt;i&gt;Cancer Res; 78(13); 3709–17. ©2018 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Conserved anti-inflammatory effects and sensing of butyrate in zebrafish (2020)

Short-chain fatty acids (SCFAs) are produced by microbial fermentation of dietary fiber in the gut. Butyrate is a particularly important SCFA with anti-inflammatory properties and is generally present at lower levels in inflammatory diseases associated with gut microbiota dysbiosis in mammals. We aimed to determine if SCFAs are produced by the zebrafish microbiome and if SCFAs exert conserved effects on zebrafish immunity as an example of the non-mammalian vertebrate immune system. We demonstrate that bacterial communities from adult zebrafish intestines synthesize all three main SCFA <i>in vitro</i>, although SCFA were below our detectable limits in zebrafish intestines <i>in vivo</i>. Immersion in butyrate, but not acetate or propionate, reduced the recruitment of neutrophils and M1-type pro-inflammatory macrophages to wounds. We found conservation of butyrate sensing by neutrophils via orthologs of the <i>hydroxycarboxylic acid receptor 1</i> (<i>hcar1</i>) gene. Neutrophils from Hcar1-depleted embryos were no longer responsive to the anti-inflammatory effects of butyrate, while macrophage sensitivity to butyrate was independent of Hcar1. Our data demonstrate conservation of anti-inflammatory butyrate effects and identify the presence of a conserved molecular receptor in fish.
Bridgehead intermediates in organic synthesis. A reproducible synthesis of adamantane-containing compounds (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBridgehead intermediates in organic synthesis. A reproducible synthesis of adamantane-containing compoundsGeorge A. Kraus and Tiberiu M. SiclovanCite this: J. Org. Chem. 1994, 59, 4, 922–923Publication Date (Print):February 1, 1994Publication History Published online1 May 2002Published inissue 1 February 1994https://pubs.acs.org/doi/10.1021/jo00083a038https://doi.org/10.1021/jo00083a038research-articleACS PublicationsRequest reuse permissionsArticle Views434Altmetric-Citations14LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Low Dose Chronic Angiotensin II Induces Selective Senescence of Kidney Endothelial Cells (2021)

Angiotensin II can cause oxidative stress and increased blood pressure that result in long term cardiovascular pathologies. Here we evaluated the contribution of cellular senescence to the effect of chronic exposure to low dose angiotensin II in a model that mimics long term tissue damage. We utilized the INK-ATTAC (p16<sup>Ink4a</sup>-Apoptosis Through Targeted Activation of Caspase 8) transgenic mouse model that allows for conditional elimination of p16<sup>Ink4a</sup> -dependent senescent cells by administration of AP20187. Angiotensin II treatment for 3 weeks induced ATTAC transgene expression in kidneys but not in lung, spleen and brain tissues. In the kidneys increased expression of ATM, p15 and p21 matched with angiotensin II induction of senescence-associated secretory phenotype genes MMP3, FGF2, IGFBP2, and tPA. Senescent cells in the kidneys were identified as endothelial cells by detection of GFP expressed from the ATTAC transgene and increased expression of angiopoietin 2 and von Willebrand Factor, indicative of endothelial cell damage. Furthermore, angiotensin II induced expression of the inflammation-related glycoprotein versican and immune cell recruitment to the kidneys. AP20187-mediated elimination of p16-dependent senescent cells prevented physiologic, cellular and molecular responses to angiotensin II and provides mechanistic evidence of cellular senescence as a driver of angiotensin II effects.
Learning Analysis-by-Synthesis for 6D Pose Estimation in RGB-D Images (2015)

Analysis-by-synthesis has been a successful approach for many tasks in computer vision, such as 6D pose estimation of an object in an RGB-D image which is the topic of this work. The idea is to compare the observation with the output of a forward process, such as a rendered image of the object of interest in a particular pose. Due to occlusion or complicated sensor noise, it can be difficult to perform this comparison in a meaningful way. We propose an approach that "learns to compare", while taking these difficulties into account. This is done by describing the posterior density of a particular object pose with a convolutional neural network (CNN) that compares observed and rendered images. The network is trained with the maximum likelihood paradigm. We observe empirically that the CNN does not specialize to the geometry or appearance of specific objects. It can be used with objects of vastly different shapes and appearances, and in different backgrounds. Compared to state-of-the-art, we demonstrate a significant improvement on two different datasets which include a total of eleven objects, cluttered background, and heavy occlusion.
Desorption electrospray ionization of aerosol particles (2007)

We have applied desorption electrospray ionization to aerosol particles. Ions were formed from aerosols by merging suspended dry particles with an electrospray of solvent in a modified ion trap mass spectrometer. Dry aerosol particles were generated using a fluidized bed powder disperser and directed toward the inlet of the mass spectrometer. A nanospray source was used to create a spray of solvent droplets directed at the inlet and at a right angle with respect to the aerosol. Ions generated by the interaction of the particles and electrospray were transferred into the ion trap mass spectrometer. Using this method, pure samples of caffeine and erythromycin A were analyzed. In addition, commonly available food and drug powders including instant cocoa powder, artificial sweetener and ibuprofen were analyzed.
Mountaintop Ocean Reflectometry with Dual Frequency GPS Signals: Experiment and Preliminary Results (2018)

Throughout the past several decades, reflected GNSS signals have been utilized to measure properties of the ocean surface. Although spaceborne receivers are often used to study surface properties, they are limited in their ability to identify and quantify error sources due to size, weight and power limitations. In this paper, we describe a mountaintop ocean reflectometry experiment performed in May 2017 on the summit of Haleakala in Maui, Hawaii. A high-gain dish antenna is steered to follow rising and setting GNSS satellites and collect their direct and reflected signals. Delay-Doppler maps from GPS L1 and L5 signals are compared and altitude estimations obtained from L1 and L5 delay waveforms are presented. By combining L1 and L5 altitude estimations, the results are close to the true receiver altitude. These results demonstrate the value of the mountaintop experiment for GNSS-reflectometry research and dual-frequency processing techniques.