gebhart/patrepeval huggingface dataset:
Proceedings of the twenty-second annual symposium on Principles of distributed computing (2003)

This volume contains the 35 papers and 16 brief announcements presented at the 22nd ACM SIGACT-SIGOPS Symposium on Principles of Distributed Computing (PODC), which was held from July 13 to 16, 2003, in Boston, Massachusetts, USA. PODC included a special celebration honoring the work of Michael Fischer. This volume includes two talks of this celebration. This year, PODC included a Special Security Track chaired by Amir Herzberg. The goal of this track was to promote interaction between the distributed computing and the security communities. This volume contains two invited talks to this Track, as well as 8 papers and 5 brief announcements (included in the count of 35 papers and 16 brief announcements above).The contributed papers were selected from 208 submissions to the regular presentations track and 18 submissions to the brief announcements track in electronic discussions and at a meeting of the program committee on March 29 and 30, 2003 at the Kendall Hotel in Cambridge, Massachusetts. The regular presentations were read and evaluated by the program committee, but were not formally refereed; it is expected that many of them will appear in more polished form in fully refereed scientific journals. A selection of papers will appear in a special issue of Distributed Computing dedicated to PODC 2003. The brief announcements were screened by the program committee based on short abstracts; it is expected that many of them will be published elsewhere (including in other conferences).
A Bacteriologic Study of Scabby-Hip Lesions from Broiler Chickens in Texas (1989)

Broilers from commercial flocks experiencing a 10-60% incidence of scabby-hip lesions at processing were examined, and selected skin lesions were cultured. Over 70% of the lesions were associated with traumatic excoriations, particularly on the caudal dorsal convexity of the birds. Most lesions were observed on birds that were 5 weeks of age or older. From the 27 specimens cultured, Clostridium perfringens was isolated in pure culture from 4 lesions and Staphylococcus species from 10 lesions. Pure cultures of staphylococci were recovered from 4 lesions, and 2-5 different staphylococci were isolated from 6 lesions. Eight staphylococci were identified as S. sciuri, 8 as S. simulans, 2 as S. epidermidis, 2 as S. lentus, 2 as S. warneri, 1 as S. cohnii, and 1 as S. intermedius. Fifty cutaneous specimens from 10 5-week-old normal broilers were cultured. A total of 197 isolates were identified including 65 S. sciuri, 52 S. lentus, 24 S. simulans, 12 S. hyicus, 11 S. warneri, 9 S. cohnii, 9 S. gallinarium, 8 S. xylosus, and 7 S. epidermidis.
A 0.11 pJ/Op, 0.32-128 TOPS, Scalable Multi-Chip-Module-based Deep Neural Network Accelerator with Ground-Reference Signaling in 16nm (2019)

This work presents a scalable deep neural network (DNN) accelerator consisting of 36 chips connected in a mesh network on a multi-chip-module (MCM) using ground-referenced signaling (GRS). While previous accelerators fabricated on a single monolithic die are limited to specific network sizes, the proposed architecture enables flexible scaling for efficient inference on a wide range of DNNs, from mobile to data center domains. The 16nm prototype achieves 1.29 TOPS/mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , 0.11 pJ/op energy efficiency, 4.01 TOPS peak performance for a 1chip system, and 127.8 peak TOPS and 2615 images/s ResNet50 inference for a 36-chip system.
Dual-Acting Cholinesterase–Human Cannabinoid Receptor 2 Ligands Show Pronounced Neuroprotection in Vitro and Overadditive and Disease-Modifying Neuroprotective Effects in Vivo (2019)

We have designed and synthesized a series of 14 hybrid molecules out of the cholinesterase (ChE) inhibitor tacrine and a benzimidazole-based human cannabinoid receptor subtype 2 (hCB<sub>2</sub>R) agonist and investigated them in vitro and in vivo. The compounds are potent ChE inhibitors, and for the most promising hybrids, the mechanism of human acetylcholinesterase (hAChE) inhibition as well as their ability to interfere with AChE-induced aggregation of β-amyloid (Aβ), and Aβ self-aggregation was assessed. All hybrids were evaluated for affinity and selectivity for hCB<sub>1</sub>R and hCB<sub>2</sub>R. To ensure that the hybrids retained their agonist character, the expression of cAMP-regulated genes was quantified, and potency and efficacy were determined. Additionally, the effects of the hybrids on microglia activation and neuroprotection on HT-22 cells were investigated. The most promising in vitro hybrids showed pronounced neuroprotection in an Alzheimer's mouse model at low dosage (0.1 mg/kg, i.p.), lacking hepatotoxicity even at high dose (3 mg/kg, i.p.).
Al-2.30 Depth of Focus (2021)

As increasingly smaller molecular materials and material structures are devised or developed for technological applications, the demands on the processes of lithography now routinely include feature sizes that are of the order of 10 nm. In reaching such a fine level of resolution, the methods of lithography have increased markedly in sophistication and brought into play 2terminology that is unfamiliar, on the one hand, to scientists tasked with the development of new lithographic materials or, on the other, to the engineers who design and operate the complex equipment that is required in modern-day processing. Publications produced by scientists need to be understood by engineers and vice versa, and these commonly arise from collaborative research that draws heavily on the terminology of two or more of the traditional disciplines. It is developments in polymer science and material science that lead progress in areas that cross traditional boundaries, such as microlithography. This document provides the exact definitions of a selection of unfamiliar terms that researchers and practitioners from different disciplines might encounter.
Study of spatial scaling in braided river patterns using synthetic aperture radar imagery (1998)

Synthetic aperture radar (SAR) imagery offers an appealing way of remotely monitoring the complex and rapidly changing forms of braided rivers. These rivers are often found in scarcely inhabited regions and are so dynamic that in situ measurements are almost impossible. In this paper, SAR imagery was used to extract braided river patterns such that their spatial scaling characteristics could be studied. From analysis of several reaches of a braided river in Alaska (the Tanana River), self‐affine spatial scaling of the river patterns was found to be present under different flow rates and in different seasons when the river was undisturbed (free of external topographic controls). In regions where predominant geologic controls (i.e., mountains) or predominant flow paths (several tens of times the size of the other channels) were present, no spatial scaling was found. When scaling was found, the values of the anisotropic scaling exponents v x and v y had very similar values to those found by Sapozhnikov and Foufoula‐Georgiou [1996] from traced and digitized aerial photographs of several braided rivers.
Increased expression and cellular localization of lipocalin‐type prostaglandin D synthase in Helicobacter pylori ‐induced gastritis (2009)

Immunological responses in the host can result in different disease outcomes of Helicobacter pylori-induced gastritis. Prostaglandin E2 derived from cyclooxygenase (COX) and prostaglandin E synthase contribute to gastric protection. Recently, prostaglandin D2 was shown to be involved in host immunity by chemotactic activity through chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), but its role in H. pylori-induced gastritis has not been clarified. We determined the expression levels of mRNAs for haematopoietic PGD synthase (H-PGDS) and lipocalin-type PGDS (L-PGDS), MIP-1 alpha, IFN-gamma, IL-4, and CDX2 in H. pylori-induced gastritis mucosa by quantitative RT-PCR. We found that L-PGDS was constitutively expressed in the epithelium of the glandular base. L-PGDS, but not H-PGDS, was induced on fibroblasts close to infiltrating cells in the H. pylori-infected gastric mucosa. These fibroblasts co-expressed COX-2. The level of L-PGDS mRNA expression decreased as gastritis became more severe. In most of the H. pylori-infected gastric mucosa, CCR5(+) cells had more actively infiltrated than had CRTH2(+) cells. However, the expression level of IFN-gamma was lower in the mucosa of the CRTH2(+) cells-dominantly infiltrating group than that of the less CRTH2-infiltrating group. Exogenously added PGD2 decreased the H. pylori-induced expression of IFN-gamma in peripheral blood mononuclear cells in vitro. The data suggest that PGD2 derived from the gastric mucosa and fibroblasts plays protective roles against inflammatory changes in H. pylori-induced gastritis.
High-performance poly-Si TFTs made by Ni-mediated crystallization through low-shot laser annealing (2003)

High-performance polycrystalline silicon (poly-Si) thin-film transistors (TFTs) have been fabricated using metal-induced crystallization followed by laser annealing (L-MIC). Laser annealing after MIC was found to yield a major improvement to the electrical characteristics of poly-Si TFTs. At a laser fluence of 330 mJ/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , the field effect mobility increased from 71 to 239 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> /Vs, and the minimum leakage current reduced from around 3.0×10/sup -12/ A/μm to 2.9×10/sup -13/ A/μm at a drain voltage of 5 V. In addition, the dependence of the TFT characteristics on the laser energy density was much weaker than that for conventional excimer laser annealed poly-Si TFTs.
Supporting group-to-group collaboration in videoconferences (2003)

Describes our experiences in an ongoing collaboration between our research group in Palo Alto and a similar group in Japan. The collaboration is based on semi-monthly videoconferences. Due to cultural and language barriers, we found it important to use a variety of communication techniques, ranging from audio and video to text-based chats. During the collaboration, we encountered a number of technical issues that caused communication breakdowns, and have taken various steps to improve the videoconferencing experience. In addition to improving the sound quality by using better microphone placements, we developed a number of systems that support different aspects of a videoconference. One of the new components is a system for panoramic two-way video communication that digitally combines images from an array of inexpensive video cameras. We also provided a means for the remote display of presentations, made design changes to our conference room and added support for taking meeting minutes and for reviewing captured videoconferences. These changes have resulted in an improved videoconferencing experience and in a more effective collaboration with our Japanese colleagues.
Clinical Evaluation of the Relationship Between Systemic Disease and the Time of Onset of Peri-Implantitis: A Retrospective Cohort Study (2022)

The role of systemic diseases in the development and progression of peri-implantitis remains unclear and requires discussion from various perspectives. This retrospective cohort study aimed to evaluate whether the type of systemic disease affects the onset time of peri-implantitis. The cohort consisted of patients who underwent implant maintenance evaluations between January 1998 and June 2020. Information on age, sex, history of periodontal disease, smoking habits, body mass index, systemic diseases, implant placement sites, and diagnosis of peri-implantitis were obtained. The relationships between the time of onset of peri-implantitis and the medical history of systemic diseases were determined statistically by applying the Kaplan-Meier analysis method and log-rank test. A total of 216 implants in 89 patients (34 male and 55 female) were included in this study. The average patient age was 53.9 ± 11.8 years at the first visit, and the mean duration of maintenance was 7 years and 4 months. A total of 43 patients had medical histories and were assigned to the systemic disease group. In this group, the overall prevalence of peri-implantitis was 25.4% (29 of 114 implants). The medical history of systemic diseases (odds ratio [OR], 6.87; 95% confidence interval [CI], 2.37-19.9) and dental history of periodontitis (OR, 3.64; 95% CI, 1.25-10.6) were assessed as risk factors for peri-implantitis. A significant difference in the time of onset of peri-implantitis was confirmed between patients with systemic disease and healthy patients. Diabetes mellitus, osteoporosis, and hypertension had a significant impact on the earlier onset of peri-implantitis.
Hypoxia-Inducible miR-210 Regulates the Susceptibility of Tumor Cells to Lysis by Cytotoxic T Cells (2012)

Hypoxia in the tumor microenvironment plays a central role in the evolution of immune escape mechanisms by tumor cells. In this study, we report the definition of miR-210 as a miRNA regulated by hypoxia in lung cancer and melanoma, documenting its involvement in blunting the susceptibility of tumor cells to lysis by antigen-specific cytotoxic T lymphocytes (CTL). miR-210 was induced in hypoxic zones of human tumor tissues. Its attenuation in hypoxic cells significantly restored susceptibility to autologous CTL-mediated lysis, independent of tumor cell recognition and CTL reactivity. A comprehensive approach using transcriptome analysis, argonaute protein immunoprecipitation, and luciferase reporter assay revealed that the genes PTPN1, HOXA1, and TP53I11 were miR-210 target genes regulated in hypoxic cells. In support of their primary importance in mediating the immunosuppressive effects of miR-210, coordinate silencing of PTPN1, HOXA1, and TP53I11 dramatically decreased tumor cell susceptibility to CTL-mediated lysis. Our findings show how miR-210 induction links hypoxia to immune escape from CTL-mediated lysis, by providing a mechanistic understanding of how this miRNA mediates immunosuppression in oxygen-deprived regions of tumors where cancer stem-like cells and metastatic cellular behaviors are known to evolve.
FiWi Networks (2013)

Optical access network is a promising solution to meet the ever-increasing demand for broadband services. Fiber-based technologies such as Fiber To The Home (FTTH), Fiber To The Building (FTTB), and Fiber To The Curb (FTTC) are well suited to support high bandwidth services and mitigate bandwidth bottlenecks. However, implementing optical fiber to all end points imposes considerable CAPEX. Moreover, fiber cannot directly reach mobile users and devices. Although untethered features of wireless networks are attractive, their limited supported bandwidth cannot answer today’s enormous demands. Combining complementary features of these two technologies for broadband access is imminent and meritorious. Thus, integrated Fiber-Wireless (FiWi) access networks are considered as a scalable and economical means for broadband access. In FiWi, end points receive services through a wireless subnetwork, which acts as the front end and is connected to the optical subnetwork, which serves as the back end via gateway nodes.
PinNPivot: Object Manipulation Using Pins in Immersive Virtual Environments (2020)

Object manipulation techniques in immersive virtual environments are either inaccurate or slow. We present a novel technique, PinNPivot, where pins are used to constrain 1DOF/2DOF/3DOF rotations. It also supports 6DOF manipulation and 3DOF translation. A comparison with three existing techniques shows that PinNPivot is significantly more accurate and faster.
Simple scheme for surface-band calculations. II. The Green's function (1981)

We present a very simple scheme for calculating the Green's function of a semi-infinite surface system described within a localized orbital basis. By generating a series of matching conditions for the Green's function we can calculate its matrix elements much faster than any method currently available. We present the formalism for a specific class of systems and include a simple example to illustrate the use of the technique.
On the Correlation between Ionization Potentials and Excitation Energies, part III: Pyrazine (1973)

Abstract A recently suggested scheme for relating ionisation potentials ( IP ) to excitation energies ( E ) has been applied to pyrazine and 2,6‐dimethylpyrazine. The results indicate that in these systems the energy gap (Δ E ) between the two lowest lying 1 n ,π*‐states is significantly smaller than that (Δ IP ) between the corresponding 2 n ‐states of the parent radical cations. The values estimated for Δ E on the basis of Δ IP , measurable by photoelectron spectroscopy, disagree with those calculated theoretically but seem to be supported by the experimental evidence available. Since Δ E = Δ IP would normally be expected, the relationship Δ E &lt; Δ IP actually present in these systems is discussed and related to the different shape of the n ‐MO's involved in the ionization and excitation processes.
An open-source bioink database for microextrusion 3D printing (2022)

3D printing has rapidly become a critical enabling technology in tissue engineering and regenerative medicine for the fabrication of complex engineered tissues. 3D bioprinting, in particular, has advanced greatly to facilitate the incorporation of a broad spectrum of biomaterials along with cells and biomolecules of interest for<i>in vitro</i>tissue generation. The increasing complexity of novel bioink formulations and application-dependent printing conditions poses a significant challenge for replicating or innovating new bioprinting strategies. As the field continues to grow, it is imperative to establish a cohesive, open-source database that enables users to search through existing 3D printing formulations rapidly and efficiently. Through the efforts of the NIH/NIBIB Center for Engineering Complex Tissues, we have developed, to our knowledge, the first bioink database for extrusion-based 3D printing. The database is publicly available and allows users to search through and easily access information on biomaterials and cells specifically used in 3D printing. In order to enable a community-driven database growth, we have established an open-source portal for researchers to enter their publication information for addition into the database. Although the database has a broad range of capabilities, we demonstrate its utility by performing a comprehensive analysis of the printability domains of two well-established biomaterials in the printing world, namely poly(ϵ-caprolactone) and gelatin methacrylate. The database allowed us to rapidly identify combinations of extrusion pressure, temperature, and speed that have been used to print these biomaterials and more importantly, identify domains within which printing was not possible. The data also enabled correlation analysis between all the printing parameters, including needle size and type, that exhibited compatibility for cell-based 3D printing. Overall, this database is an extremely useful tool for the 3D printing and bioprinting community to advance their research and is an important step towards standardization in the field.
In‐Memory Computing with Memristor Content Addressable Memories for Pattern Matching (2020)

The dramatic rise of data-intensive workloads has revived application-specific computational hardware for continuing speed and power improvements, frequently achieved by limiting data movement and implementing "in-memory computation". However, conventional complementary metal oxide semiconductor (CMOS) circuit designs can still suffer low power efficiency, motivating designs leveraging nonvolatile resistive random access memory (ReRAM), and with many studies focusing on crossbar circuit architectures. Another circuit primitive-content addressable memory (CAM)-shows great promise for mapping a diverse range of computational models for in-memory computation, with recent ReRAM-CAM designs proposed but few experimentally demonstrated. Here, programming and control of memristors across an 86 × 12 memristor ternary CAM (TCAM) array integrated with CMOS are demonstrated, and parameter tradeoffs for optimizing speed and search margin are evaluated. In addition to smaller area, this memristor TCAM results in significantly lower power due to very low programmable conductance states, motivating CAM use in a wider range of computational applications than conventional TCAMs are confined to today. Finally, the first experimental demonstration of two computational models in memristor TCAM arrays is reported: regular expression matching in a finite state machine for network security intrusion detection and definable inexact pattern matching in a Levenshtein automata for genomic sequencing.
Grouptron: Dynamic Multi-Scale Graph Convolutional Networks for Group-Aware Dense Crowd Trajectory Forecasting (2022)

Accurate, long-term forecasting of pedestrian trajectories in highly dynamic and interactive scenes is a longstanding challenge. Recent advances in using data-driven approaches have achieved significant improvements in terms of prediction accuracy. However, the lack of group-aware analysis has limited the performance of forecasting models. This is especially nonnegligible in highly crowded scenes, where pedestrians are moving in groups and the interactions between groups are extremely complex and dynamic. In this paper, we present Grouptron, a multi-scale dynamic forecasting framework that leverages pedestrian group detection and utilizes individual-level, group-level and scene-level information for better understanding and representation of the scenes. Our approach employs spatio-temporal clustering algorithms to identify pedestrian groups, creates spatio-temporal graphs at the individual, group, and scene levels. It then uses graph neural networks to encode dynamics at different scales and aggregate the embeddings for trajectory prediction. We conducted extensive comparisons and ablation experiments to demonstrate the effectiveness of our approach. Our method achieves 9.3% decrease in final displacement error (FDE) compared with state-of-the-art methods on ETH/UCY benchmark datasets, and 16.1% decrease in FDE in more crowded scenes where extensive human group interactions are more frequently present.
Relevance of immunoglobulin G Fc receptor polymorphism to recurrence of adult periodontitis in Japanese patients (1997)

Polymorphonuclear neutrophil (PMN) phagocytic function has been shown to be impaired in some patients with periodontitis. PMN constitutively express members of two immunoglobulin G receptor (Fc gammaR) classes: Fc gammaRIIa (CD32) and Fc gammaRIIIb (CD16). Both receptors exhibit genetically determined structural and functional biallelic polymorphisms, which have been shown to influence PMN phagocytic function. In this study, we assessed the relevance of these Fc gammaR polymorphisms to susceptibility to adult periodontitis and recurrence rate. The distribution of Fc gammaRIIa and Fc gammaRIIIb genotypes of 100 Japanese patients with adult periodontitis during follow-up was compared to the distribution of genotypes in 105 race-matched healthy controls. No significant skewing of distributions of Fc gammaRIIa and Fc gammaRIIIb genotypes was observed between patients and controls. Notably, however, a significant overrepresentation of the Fc gammaRIIIb-NA2 allotype was found in patients with disease recurrence (P < 0.05; odds ratio, 4.29; 95% confidence interval, 1.19 to 16.24). Moreover, the annual rate of recurrence was significantly higher in patients with the Fc gammaRIIIb-NA2/NA2 and Fc gammaRIIIb-NA1/NA2 genotypes than in Fc gammaRIIIb-NA1/NA1 individuals (P < 0.05). Fc gammaRIIa-R/R131 individuals also exhibited higher recurrence rates, though the difference was not statistically significant (P = 0.06). These results suggest that the Fc gammaRIIIb-NA2 allotype represents a risk factor for recurrence of adult periodontitis.