gebhart/patrepeval huggingface dataset:
Selective Lead Ion Sensor Based on the CuO Nanoshuttles (2013)

In this research work, CuO nanoshuttles like nanostructures are synthesized by hydrothermal method using polyvinyl alcohol surfactant and the structural characterisation was carried out using scanning electron microscopy (SEM) and X-ray diffraction (XRD) techniques. The structural studies showed the high yield of the CuO nanostructures on the substrate and also exhibit good crystal quality. Moreover, CuO nanoshuttles like nanostructures were utilized for the development of lead ion sensor electrode and the sensor electrode has shown the linear potentiometric response for the lead ions over the wide range of 5 x 10(-6) M-1 x 10(-1) M with a Nernstian slope of 31 mV/decade. The advantageous features of the proposed sensor electrode include high selectivity, repeatability, low limit of detection (1 x 10(-7) M) and a fast response time of less than 10 s, good stability, and the reproducibility. The CuO nanoshuttles based lead ion sensor electrode was used as an indicator electrode for the potentiometric titration of lead ions against the etthylenediaminetetraacetic acid (EDTA). All the obtained results indicate that the presented lead ion sensor may have a good potential for its utilization in the real sample analysis.
De novo expression of human polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6) in colon adenocarcinoma inhibits the differentiation of colonic epithelium (2017)

Aberrant expression of <i>O</i>-glycans is a hallmark of epithelial cancers. Mucin-type <i>O-</i>glycosylation is initiated by a large family of UDP-GalNAc:polypeptide <i>N</i>-acetylgalactosaminyltransferases (GalNAc-Ts) that target different proteins and are differentially expressed in cells and organs. Here, we investigated the expression patterns of all of the GalNAc-Ts in colon cancer by analyzing transcriptomic data. We found that GalNAc-T6 was highly up-regulated in colon adenocarcinomas but absent in normal-appearing adjacent colon tissue. These results were verified by immunohistochemistry, suggesting that GalNAc-T6 plays a role in colon carcinogenesis. To investigate the function of GalNAc-T6 in colon cancer, we used precise gene targeting to produce isogenic colon cancer cell lines with a knockout/rescue system for <i>GALNT6</i> GalNAc-T6 expression was associated with a cancer-like, dysplastic growth pattern, whereas <i>GALNT6</i> knockout cells showed a more normal differentiation pattern, reduced proliferation, normalized cell-cell adhesion, and formation of crypts in tissue cultures. <i>O-</i>Glycoproteomic analysis of the engineered cell lines identified a small set of GalNAc-T6-specific targets, suggesting that this isoform has unique cellular functions. In support of this notion, the genetically and functionally closely related GalNAc-T3 homolog did not show compensatory functionality for effects observed for GalNAc-T6. Taken together, these data strongly suggest that aberrant GalNAc-T6 expression and site-specific glycosylation is involved in oncogenic transformation.
Open Data from the Third Observing Run of LIGO, Virgo, KAGRA, and GEO (2023)

Abstract The global network of gravitational-wave observatories now includes five detectors, namely LIGO Hanford, LIGO Livingston, Virgo, KAGRA, and GEO 600. These detectors collected data during their third observing run, O3, composed of three phases: O3a starting in 2019 April and lasting six months, O3b starting in 2019 November and lasting five months, and O3GK starting in 2020 April and lasting two weeks. In this paper we describe these data and various other science products that can be freely accessed through the Gravitational Wave Open Science Center at https://gwosc.org . The main data set, consisting of the gravitational-wave strain time series that contains the astrophysical signals, is released together with supporting data useful for their analysis and documentation, tutorials, as well as analysis software packages.
Multi-tap digital canceller for full-duplex applications (2017)

We identify phase noise as a bottleneck for the performance of digital self-interference cancellers that utilize a single auxiliary receiver - single-tap digital cancellers - and operate in multipath propagation environments. Our analysis demonstrates that the degradation due to phase noise is caused by a mismatch between the analog delay of the auxiliary receiver and the different delays of the multipath components of the self-interference signal. We propose a novel multi-tap digital self-interference canceller architecture that is based on multiple auxiliary receivers and a customized Normalized-Least-Mean-Squared (NLMS) filtering for self-interference regeneration. Our simulation results demonstrate that our proposed architecture is more robust to phase noise impairments and can in some cases achieve 10 dB larger self-interference cancellation than the single-tap architecture.
Force-field functor theory: classical force-fields which reproduce equilibrium quantum distributions (2013)

Feynman and Hibbs were the first to variationally determine an effective potential whose associated classical canonical ensemble approximates the exact quantum partition function. We examine the existence of a map between the local potential and an effective classical potential which matches the exact quantum equilibrium density and partition function. The usefulness of such a mapping rests in its ability to readily improve Born-Oppenheimer potentials for use with classical sampling. We show that such a map is unique and must exist. To explore the feasibility of using this result to improve classical molecular mechanics, we numerically produce a map from a library of randomly generated one-dimensional potential/effective potential pairs then evaluate its performance on independent test problems. We also apply the map to simulate liquid para-hydrogen, finding that the resulting radial pair distribution functions agree well with path integral Monte Carlo simulations. The surprising accessibility and transferability of the technique suggest a quantitative route to adapting Born-Oppenheimer potentials, with a motivation similar in spirit to the powerful ideas and approximations of density functional theory.
A High-Efficiency, Low-NOx Burner for Oxy-Gas Glass Furnaces (2008)

Switching from air-gas to oxy-gas combustion in glass furnaces offers the advantages of reduced energy costs, lower NOx and particulate emissions, and decreased capital and maintenance costs by eliminating flue gas cleaning and heat recovery regenerators. Oxy-gas flames burn at higher temperatures, providing energy savings through more efficient radiant heat transfer and higher energy availability. Low N0X levels result from the reduced amount of nitrogen in the flame. At high oxy-gas flame temperatures, the combustion products are not luminous (low emissivity), which limits process efficiency and production rate and results in higher-than-necessary fuel and oxygen consumption. The Institute of Gas Technology (IGT) and Combustion Tec, Inc., (CTI) have completed laboratory testing of 0.5 MMBtu/h versions of a high-luminosity, low-NOx oxy-gas burner and are preparing a 3 MMBtu/h version for testing. This IGT-patented burner produces a highly luminous flame by forming and then burning soot in the flame. Tests show an increase in heat transfer to the load of more than 12%, a significant decrease in NOx emissions compared with other oxy-gas burners, a flame shape with larger coverage of the load, and a reduction in exhaust gas temperatures by more than 100°F compared with commercial low-NOx oxy-gas burners. Even greater increases in heat transfer and reductions in NOx are expected in the first commercial demonstration next year.
Laser produced plasma light source for next generation lithography (2003)

Summary form only given, as follows. Our group is part of the Japanese Extreme Ultraviolet Lithography System Development Association and working on laser produced plasma light sources. The system we developed since the project start last year is based on Xenon as a plasma source. Being continuously recycled the Xenon is injected into the vacuum chamber via a small diameter nozzle A Master Oscillator Power Amplifier (MOPA) Nd:YAG laser system oscillating at 1064 nm and a maximum repetition rate of 10 kHz is used for plasma generation. For various Xenon target and laser parameters, including two laser pulse durations of several ns and 30 ns (fwhm), we evaluated plasma characteristics relevant for lithography systems including emission spectra, in-band energy, energy stability and EUV conversion efficiency, out-of-band energy and EUV emission symmetry. Beside plasma characteristics, the lifetime of the collector mirror placed inside the vacuum chamber near the plasma will be a critical issue being strongly correlated to plasma debris and ion impact. Xenon debris can be due to Xe solid phase formation on the mirror surface but might, be reduced by the heat load of the mirror. In a first step we concentrated therefore on time-of-flight measurements in order to measure energy distributions of ions emitted from the generated plasmas.
Artificial intelligence in liver disease (2021)

Artificial intelligence (AI) is a branch of computer science that attempts to mimic human intelligence, such as learning and problem-solving skills. The use of AI in hepatology occurred later than in gastroenterology. Nevertheless, studies on applying AI to liver disease have recently increased. AI in hepatology can be applied for detecting liver fibrosis, differentiating focal liver lesions, predicting prognosis of chronic liver disease, and diagnosing of nonalcoholic fatty liver disease. We expect that AI will eventually help manage patients with liver disease, predict the clinical outcomes, and reduce medical errors. However, there are several hurdles that need to be overcome. Here, we will briefly review the areas of liver disease to which AI can be applied.
Thermoacoustic Modeling of a Gas Turbine Using Transfer Functions Measured Under Full Engine Pressure (2010)

Thermoacoustic transfer functions of a full-scale gas turbine burner operating under full engine pressure have been measured. The excitation of the high-pressure test facility was done using a siren that modulated a part of the combustion airflow. Pulsation probes have been used to record the acoustic response of the system to this excitation. In addition, the flame’s luminescence response was measured by multiple photomultiplier probes and a light spectrometer. Three techniques to obtain the thermoacoustic transfer function are proposed and employed: two acoustic-optical techniques and a purely acoustic technique. The first acoustical-optical technique uses one single optical signal capturing the chemiluminescence intensity of the flame as a measure for the heat release in the flame. This technique only works if heat release fluctuations in the flame have only one generic source, e.g., equivalence ratio or mass flow fluctuations. The second acoustic-optical technique makes use of the different response of the flame’s luminescence at different optical wavelengths bands to acoustic excitation. It also works, if the heat release fluctuations have two contributions, e.g., equivalence ratio and mass flow fluctuation. For the purely acoustic technique, a new method was developed in order to obtain the flame transfer function, burner transfer function, and flame source term from only three pressure transducer signals. The purely acoustic method could be validated by the results obtained from the acoustic-optical techniques. The acoustic and acoustic-optical methods have been compared and a discussion on the benefits and limitations of each is given. The measured transfer functions have been implemented into a nonlinear, three-dimensional, time domain network model of a gas turbine with an annular combustion chamber. The predicted pulsation behavior shows a good agreement with pulsation measurements on a field gas turbine.
An Introduction to the Speech Enhancement for Augmented Reality (Spear) Challenge (2022)

It is well known that microphone arrays can be used to enhance a target speaker in a noisy, reverberant environment, with both spatial (e.g. beamforming) and statistical (e.g. source separation) methods proving effective. Head-worn microphone arrays inherently sample a sound field from an egocentric perspective — when the head moves the apparent direction of even static sound sources change with respect to the array. Traditionally, enhancement algorithms have aimed at being robust to head motion but hearable devices and augmented reality (AR) headsets/glasses contain additional sensors which offer the potential to adapt to, or even exploit, head motion. The recently released EasyCom database contains microphone array recordings of group conversations made in a realistic restaurant-like acoustic scene. In addition to egocentric recordings made with AR glasses, extensive metadata, including the position and orientation of speakers, is provided. This paper describes the use and adaptation of EasyCom for a new IEEE SPS Data Challenge.
(R2PC2H4PR2)Pd0−1-Alkyne Complexes (1997)

Displacement of the ethene ligand in (dippe)Pd(C2H4) (dippe = iPr2PC2H4PiPr2) by 1-alkynes RC⋮CH affords the mononuclear complexes (dippe)Pd(RC⋮CH) (R = Me (2a), Ph (3a), CO2Me (4), SiMe3 (5)). The molecular structure of 3a has been determined by X-ray crystallography. Mononuclear 2a and 3a have been reacted with stoichiometric amounts of (dippe)Pd(η1-C3H5)2 as a source for [(dippe)Pd0] to yield the dinuclear derivatives {(dippe)Pd}2(μ-RC⋮CH) (R = Me (2b), Ph (3b)). By the reaction of (dippe)Pd(C2H4) with difunctional vinylacetylene the mononuclear complex (dippe)Pd{(1,2-η2)-RC⋮CH} (R = CHCH2 (6a)) is formed, which is in equilibrium with isomeric (dippe)Pd{(3,4-η2)-H2CCHC⋮CH} (6b). Addition of [(dippe)Pd0] to 6a,b yields dinuclear {(dippe)Pd}2(μ-RC⋮CH) (R = CHCH2 (6c)). Reaction of (dippe)Pd(C2H4) with butadiyne affords (dippe)Pd(η2-HC⋮CC⋮CH) (7c). From dippe, Pt(cod)2, and C4H2 the Pt homologue has also been synthesized and thus, together with the already known Ni derivative, the series (dippe)M(η2-HC⋮CC⋮CH) (M = Ni (7a), Pd (7c), Pt (7f)) is now complete. When 7c and [(dippe)Pd0] are combined, the dinuclear complex {(dippe)Pd}2(μ-RC⋮CH) (R = C⋮CH (7e)) is formed in solution, whereas isomeric {(dippe)Pd}2{μ-(1,2-η2):(3,4-η2)-HC⋮CC⋮CH} (7d) is present in the solid state. The preparation of the Pd0−1-alkyne complexes refutes the conventional wisdom that this type of compound is inherently unstable. By reaction of (dippe)Pd(C2H4) with internal alkynes C2R2 the complexes (dippe)Pd(RC⋮CR) (R = Me (8a), Ph (9), CO2Me (10), SiMe3 (11)) have also been prepared. Combining 8a with [(dippe)Pd0] affords dinuclear {(dippe)Pd}2(μ-MeC⋮CMe) (8b). Finally, solution thermolysis of 2b and 8b gives rise to dinuclear alkyne-free Pd2(dippe)2 (12).
Silica (2008)

Abstract Silica (SiO 2 ) is a commonly occurring compound in nature. Various crystalline and noncrystalline silica minerals of inorganic and biogenic origin are known. Depending on temperature, pressure, composition of the precursor phases, etc., several different crystalline modifications are formed. Quartz is the most abundant and well‐known polymorph. Silica occurs as meter‐sized quartz crystals or as amorphous masses made up of submicroscopic crystallites having different microstructures or growth fabrics. In addition, synthetic polymorphs have been produced for which no natural counterparts exist. In industry, quartz sand and silica rocks are widely used as raw materials for production of glass, ceramics, and silicon. Single crystals of quartz are grown artificially for application as resonator crystals in clocks, communication technology, and computer electronics. Both natural and synthetic silica powders are used as fillers to improve the mechanical properties of plastics. The article contains sections titled: 1. Silica Modifications and Products 1.1. Occurrence and Geochemistry 1.2. Si‐O Bond and Crystal Structures 1.3. Crystalline Silica Phases 1.3.1. Crystalline Silica Minerals 1.3.2. Crystalline Nonmineral Silica Phases 1.4. Noncrystalline Silica Minerals 1.5. Colored Silica Minerals 1.6. Silica Rocks 1.7. Crystalline Silica Products 1.7.1. Cultured Quartz Single Crystals 1.7.2. Polycrystalline Silica Products 1.8. Noncrystalline Silica Products 2. Quartz Raw Materials 2.1. Physical Forms and Occurrence 2.2. Processing 2.3. Uses 3. Diatomites 3.1. Introduction 3.2. Formation, Composition, and Quality Criteria 3.3. Occurrence and Mining 3.4. Processing 3.5. Analysis 3.6. Storage and Transport 3.7. Environmental and Health Protection 3.8. Uses 3.9. Recycling 4. Colloidal Silica 4.1. Introduction 4.2. Structure of Colloidal Silica Particles 4.3. Physical and Chemical Properties 4.4. Stability 4.5. Production 4.6. Analysis and Characterization 4.7. Uses 4.8. Storage, Handling, and Transportation 4.9. Economic Aspects 5. Silica Gel 5.1. Introduction 5.2. Structure, Properties, and Characterization 5.3. Production 5.4. Uses 5.5. Economic Aspects 5.6. Legal Aspects 6. Pyrogenic Silica 6.1. Flame Hydrolysis 6.1.1. Production Process 6.1.2. Morphology 6.1.3. Solid‐State Properties 6.1.4. Surface Chemistry 6.1.5. Surface Modification with Silicon Compounds 6.1.6. Characterization <jats:styled-cont
Effects of diabetes on protein turnover in cardiac muscle (1980)

Effects of alloxan diabetes of 10-day duration on protein turnover were investigated in hearts perfused with buffers simulating control and diabetic sera. Diabetes produced a 30% inhibition of protein synthesis in hearts perfused as Langendorff or working preparations. This reduction was attributable to a 20% fall in RNA concentration and a 10% decrease in efficiency of protein synthesis. Determination of RNA in ribosomal subunits indicated that the reduction in efficiency that was observed with diabetes may be due to an inhibition of polypeptide chain elongation/termination. Pharmacological levels of insulin (25 mU/ml) and cardiac work stimulated protein synthesis in both control and diabetic hearts. Effects of diabetes and insulin on protein synthesis in isolated heart muscle cells were similar to those found in whole heart. Diabetes increased protein degradation in hearts perfused with buffer similating diabetic serum and under conditions of cardiac work. Insulin (25 mU/ml) decreased protein degradation in both control and diabetic hearts. These studies indicate that long-term diabetes produces a greater negative nitrogen balance that, in contrast to control hearts, cannot be normalized by pharmacological levels of insulin or by cardiac work.
Discovery and Development of the HCV NS3/4A Protease Inhibitor Danoprevir (ITMN‐191/RG7227) (2011)

This chapter contains sections titled: Introduction Discovery Synthesis Structural Biology Biochemical Characteristics In Vitro Pharmacology Nonclinical Pharmacokinetics Clinical Experience Conclusions and Future Prospects References
Choosing Autonomy Modes for Multirobot Search (2010)

Search tasks, such as foraging or perimeter control, account for many of the near-term applications envisioned for multirobot teams. The results support the choice of task-centered architectures in which the control and coordination of robotic platforms is automated, leaving search and identification of targets to human operators.
Separation of the reagent ions from the reagent gas in ammonia chemical ionization mass spectrometry (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSeparation of the reagent ions from the reagent gas in ammonia chemical ionization mass spectrometryRobert B. CodyCite this: Anal. Chem. 1989, 61, 22, 2511–2515Publication Date (Print):November 15, 1989Publication History Published online1 May 2002Published inissue 15 November 1989https://doi.org/10.1021/ac00197a012Request reuse permissionsArticle Views67Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alertsclose Get e-Alerts
Alterations in Multi‐Scale Cardiac Architecture in Association With Phosphorylation of Myosin Binding Protein‐C (2016)

We conclude that phosphorylation of MYBPC3 contributes to the genesis of ventricular wall geometry, linking myofilament biology with multiscale cardiac mechanics and myoarchitecture.
Incidence and predictive factors of Balkan Endemic Nephropathy: A longitudinal study (2014)

Balkan endemic nephropathy (BEN) is a chronic kidney disease that progresses slowly. There are no known clinical markers to identify an early disease development. We evaluated the relationship between parental history of BEN and clinical markers as predictors of new occurrences of BEN. A 5-year prospective study in the offsprings of BEN and control patients was conducted in Vratza, Bulgaria, between 2003 and 2009 using markers in years one and three to predict new cases of BEN in the year five. We defined incident cases of BEN based on parental history, reduced kidney size and reduced kidney function, distinguishing probable and definite BEN, both combined as total incidence. The data were analyzed by Cox regression models using age as time scale and controlling for gender. We estimated hazard ratios and their 95% confidence intervals. The incidence of BEN was 17.4%. Paternal history was strongly associated with all three incidence groups (hazards ratio: 27-68, P <0.05). A reduction of kidney size of 1 mm resulted in a 5% increased hazard. However, taking parental history of BEN into account, these associations lost their significance. No kidney function measures were associated with new onset of BEN. A parental history of BEN is more important than clinical markers predicting the incidence of BEN. Without this information, kidney length forecasts probable BEN and the total incidence, while none of any clinical markers was related to definite BEN.