gebhart/patrepeval huggingface dataset:
ARTIFICIAL CONVERSATIONAL COMPANIONS - A Requirements Analysis (2012)

This paper is based on several attempts to provide a definition of an Artificial Companion that can be found in the referenced literature.Although accepted by the research community, such descriptions set very high expectations of such agents, but they do not address the technical feasibility and the system limitations, that is why they need an elaborated and precise explanation.In this paper, we focus on computer agents that simulate human language behaviour, and are aimed to serve, to assist and to accompany their owner over a long period of time, that we call Artificial Conversational Companions.This is the first approach to analyse the effort required to meet the expectations of Artificial Conversational Companion and discuss the identified design issues.
Fabrication and Optical Properties of ZnO Quantum Dots (2007)

Using a simple process of the deposition of ZnO thin films on SiOx/Si substrates and subsequent thermal annealing, we fabricated ZnO quantum dots embedded in silicon oxide matrix. The ZnO quantum dots were characterized using transmission electron microscopy and timeintegrated photoluminescence. The photoluminescence of the quantum dots show a blue-shift of 47 meV due to the quantum confinement effect.
Advanced modulation formats tutorial (2007)

The tutorial consists of slides covering the following: the role of modulation formats in optical communication systems; modulation formats and digital communication techniques; the anatomy of a digital communication signal; modulation and multiplexing; coherent demodulation and polarization multiplexing; line coding and FEC. (33 pages)
Urban Maps of Social Activity (2018)

Recreational queries from users looking for ideas of what to do or see and where to go are very common in desktop, mobile and, increasingly, contextual search scenarios. Such queries typically contain what, where, when components as the user seeks future activities, whether in real-time or future trip planning. Often, the user will have additional constraints and requirements for what they are seeking, such as suitability for kids, budget, for a romantic date, etc. Currently, simple recreational queries (e.g. ``restaurants in Mountain View’'' are served by static local results, or the Points of Interest thumbnail carousel (e.g. ``things to see in San Francisco''). More complex recreational queries, such as ``romantic places to eat in San Francisco friday night'', or ``educational places to visit with kids nearby'' require the user to click on the 10 blue links to read through articles from sites such as TripAdvisor and WikiTravel to satisfy their needs. Employing location based social network data, we construct urban maps of social activity for answering recreational queries using a model based on social, geographical, and temporal information. We demonstrate the feasibility of our approach using a data set of 1B check-ins.
Inhibition of murine granulopoiesis in vitro by dexamethasone (1976)

The effect of dexamethasone on mouse bone marrow granulocyte-monocyte precursor cells (CFU-C) was studied in vitro. Dexamethasone inhibited colony formation in the presence of maximally stimulating concentrations of colony-stimulating activity. A mean colony reduction of 55% occurred at 10(-9) M dexamethasone and inhibition was observed at concentrations as low as 10(-12)M. The dexamethasone suppression could be abrogated by progesterone. These studies provide evidence that the committed granulocyte-monocyte stem cell has a glucocorticoid receptor mechanism that when activated results in inhibition of cellular proliferation in vitro.
Clinical reasoning in traditional medicine exemplified by the clinical encounter of Korean medicine (2020)

Future research should focus on the similarities and differences in understanding clinical reasoning in KM as well as the broader field of traditional East Asian Medicine.
Textpresso: An Ontology-Based Information Retrieval and Extraction System for Biological Literature (2004)

We have developed Textpresso, a new text-mining system for scientific literature whose capabilities go far beyond those of a simple keyword search engine. Textpresso's two major elements are a collection of the full text of scientific articles split into individual sentences, and the implementation of categories of terms for which a database of articles and individual sentences can be searched. The categories are classes of biological concepts (e.g., gene, allele, cell or cell group, phenotype, etc.) and classes that relate two objects (e.g., association, regulation, etc.) or describe one (e.g., biological process, etc.). Together they form a catalog of types of objects and concepts called an ontology. After this ontology is populated with terms, the whole corpus of articles and abstracts is marked up to identify terms of these categories. The current ontology comprises 33 categories of terms. A search engine enables the user to search for one or a combination of these tags and/or keywords within a sentence or document, and as the ontology allows word meaning to be queried, it is possible to formulate semantic queries. Full text access increases recall of biological data types from 45% to 95%. Extraction of particular biological facts, such as gene-gene interactions, can be accelerated significantly by ontologies, with Textpresso automatically performing nearly as well as expert curators to identify sentences; in searches for two uniquely named genes and an interaction term, the ontology confers a 3-fold increase of search efficiency. Textpresso currently focuses on Caenorhabditis elegans literature, with 3,800 full text articles and 16,000 abstracts. The lexicon of the ontology contains 14,500 entries, each of which includes all versions of a specific word or phrase, and it includes all categories of the Gene Ontology database. Textpresso is a useful curation tool, as well as search engine for researchers, and can readily be extended to other organism-specific corpora of text. Textpresso can be accessed at http://www.textpresso.org or via WormBase at http://www.wormbase.org.
Generating readable texts for readers with low basic skills (2005)

Most NLG systems generate texts for readers with good reading ability, but SkillSum adapts its output for readers with poor literacy. Evaluation with lowskilled readers confirms that SkillSum's knowledge-based microplanning choices enhance readability. We also discuss future readability improvements.
SCREENING OF NEWBORN INFANTS FOR HYPOTHYROIDISM TWO YEARS' EXPERIENCE IN SOUTH AUSTRALIA (1979)

Over a period of two years, 40,000 newborn infants in South Australia have been screened for congenital hypothyroidism by the measurement of thyroxine and, on selected samples, of thyroid stimulating hormone. Samples were those obtained for an established newborn screening programme in the State. Eight infants with hypothyroidism were detected; in seven, this was due to congenital agenesis of the thyroid gland and one infant had residual thyroid tissue. A further three sick infants had abnormalities of thyroid function; in two, this was transient and reverted to normal after several weeks and the third infant died. Three infants had thyroxine-binding globulin deficiency.
Abstract 15728: Machine Learning Helps Predict Short and Intermediate-term Risk for All Cause Mortality in Patients Undergoing Percutaneous Coronary Intervention (2020)

Background: Identifying patients at a high risk of mortality post percutaneous coronary intervention (PCI) is of vital clinical importance. We investigated the utility of machine learning algorithms to predict short and intermediate-term risk of all-cause mortality in patients undergoing PCI. Methods: Patient-level demographics, clinical, electrocardiographic ,echocardiographic and angiographic data from January 2006 to December 2017 were extracted from the Mayo Clinic CathPCI registry and clinical records. For patients with multiple PCI events, data collected at the time of the index PCI was used for analysis. Patients who underwent bailout coronary artery bypass graft surgery (CABG) prior to discharge were excluded. 306 variables were incorporated into random forest machine learning model (RF) to predict all-cause mortality at 6 months and 1 year after PCI. Ten-fold cross-validation repeated five times was used to optimize the hyperparameters and estimate its external performance. The National Cardiovascular Data Registry (NCDR) based logistic regression model was used for comparison. The area under receiver operator characteristic curves (AUC) was calculated to assess the ability of the models to predict all-cause mortality. Results: A total of 17356 unique patients were included for the final analysis after excluding 165 patients who underwent CABG surgery during the index hospitalization. The mean age was 66.9 ± 12.5 years;71% were male. Indications for PCI were ST-elevation myocardial infarction (9.4%), non-ST elevation myocardial infarction (12.9%), unstable angina (17.7%), and stable angina (52.8%) in the cohort. In-hospital, 6-month &amp; 1 year mortality rates were 1.9%,4.2% &amp; 5.8% respectively. The RF model was superior to the NCDR model in predicting inhospital, 6-month, 1 year mortality (p&lt;0.0001) ( Figure 1 ). Conclusion: Machine learning is superior to NCDR model in predicting short and intermediate risk of all-cause mortality post PCI.
A Stereoselective Palladium‐Mediated Reductive Coupling of Electron‐Deficient Terminal Iodoalkenes (2008)

In the communication published with the author names Andrei S. Batsanov, Jonathan P. Knowles, Benedict Samsam and Andrew Whiting, in Issue 2, 2008, pp. 227–233 (DOI: 10.1002/adsc.200700464), the last name of the third author is Sansam, and not Samsam. The correct citation of this publication is therefore: A. S. Batsanov, J. P. Knowles, B. Sansam, A. Whiting, Adv. Synth. Catal. 2008, 350, 227–233. The authors apologize for this oversight.
Testability: Barriers to Acceptance (1986)

Design for testability sounds wonderful in theory, but if it is not used, or worse used to disadvantage, what good is it? With today's escalating technology and management's fear of commitment to a costly testing program, DFT practices are suffering. the author discusses the prominent barriers to accepting design for test: the impact of more advanced technology, the misunderstood role of testing, the lack of management's global view of sthe testing process, and the lack of integrasted tools. Testability standards are briefly discussed as a possible way to overcome these barriers.
Continuous Improvement in Wellbore Position Accuracy: Ultra-Extended-Reach Drilling in Far Eastern Russia (2018)

Abstract Drilling ultra-extended-reach (ultra-ERD) wellbores has redefined industry standards. Operators and service companies must fully assess the accompanying risks to maximize the overall productivity of an asset. New drilling technologies, such as improved drilling fluid design and geomechanics analyses, allow wellbores to be drilled to the lateral displacement of greater than 13 km. This requires improved absolute wellbore positioning, in conjunction with reduced uncertainties. When developing these drilling technologies, the economics must be considered so as not to exponentially increase the cost per barrel of oil. The increase in infill drilling of nearby offset wellbores requires developing improved methods that reduce wellbore position uncertainty when placing the wellbore in the reservoir, in addition to avoiding collisions. The proposed geomagnetic referencing technique is suitable for the application to the Sakhalin-1 project in eastern Russia. Here there is a predominance of ultra-ERD wellbores coupled with considerable knowledge of the varying depth of the basement rock structure. This paper presents a process used for creating a geomagnetic crustal field model that can be updated to the actual survey location with the date and time for real-time application. This process can also be used in the reprocessing of legacy measurement-while-drilling (MWD) data. The application of this process significantly improves wellbore position accuracy. The ability to have a greater understanding of the overall geomagnetic field, along with enhanced techniques in multistation algorithm processing, removes the effects of drillstring and the cross-axial interference due to mud shielding effects. Additional benefits of this application include reduced wellbore tortuosity for planned wells, improved anticollision separation factors, and improved torque and drag profiles. This new geomagnetic model, updated to the actual survey location, date, and time and incorporating realistic uncertainty determinations based on basement rock depth analysis, has resulted in a 50% improvement in the overall ellipse of uncertainty (EOU) when compared with previous definitive surveys, in addition to an accurate bottomhole location. Incorporating these advanced techniques reduces position uncertainty that improves overall 3D wellbore positioning. Other studies, such as a disturbance field study, evaluate the effects of the magnetospheric ring current, auroral electrojets, and secondary induced fields, and was conducted by analyzing the magnetic observatory data from the same magnetic latitude to quantify the maximum and minimum declination variations during a magnetic storm.
Surface properties of phorbol esters and their interaction with lipid monolayers and bilayers. (1975)

The potent tumor-promoting agent 12-O-tetradecanoylphorbol-13-acetate (TPA) is surface active and was found to occupy a limiting area of 62 sq A/molecule in monolayers at the air-water interface. The interfacial tension of aqueous TPA solutions is decreased by increasing the bulk-phase TPA concentrations up to 2 x 10(-6) M,beyond which no further decreases were observed. This concentration is in agreement with the apparent solubility limit previously obtained. The apparent aqueous solubility limit of the more hydrophobic phorbol-didecanoate is 5 x 10(-8) M. Interaction of TPA with egg phosphatidylcholine monolayers at the air-water interface was shown by an increase in the surface pressure of the monolayer from 22 dynes/cm, initial film pressure, to 34 dynes/cm 90 min after introduction of TPA into the aqueous subphase. It was shown by gel filtration chromatography that a similar phorbol derivative, tritiated phorbol-didecanoate, binds to phospholipid vesicles. Differential scanning calorimetry also indicated that the addition of either TPA or an inactive stereoisomer, 4-alpha-phorbol-didecanoate, to phospholipid bilayers results in a marked reduction of the enthalphy of the minor transition of dipalmitoylphosphatidylcholine liposomes. Several fluorescence polarization probes for membrane fluidity indicate that TPA does not affect this membrane parameter. Further, the presence of TPA induces no measurable change in the cation permeability of phospholipid vesicles, the conductance of planar bilayer membranes, or the electrophoretic mobility of negatively charged liposomes. The lack of a specific effect with bilayers alone, combined with the documented physiological effects at low TPA concentrations, point to the possibility of a specific membrane component as the receptor for TPA at the plasma membrane.
Mechanistic Understanding of Cr Poisoning of Solid Oxide Fuel Cell Cathodes (2009)

Abstract not Available.
Respiratory function during enzyme replacement therapy in late-onset Pompe disease: longitudinal course, prognostic factors, and the impact of time from diagnosis to treatment start (2020)

FVC stability over 5 years suggests that respiratory function is preserved during long-term ERT in real-world settings. Early initiation of alglucosidase alfa was associated with preservation of FVC in LOPD patients with better respiratory function at the time of treatment initiation.
Viral proteins expressed on the surface of murine leukemia cells (1977)

Leukemic cells of AKR mice contain as constituents of their membranes the murine leukemia virus envelope protein gp70 and the precursor polyprotein of the viral internal (core) structural proteins. Both gp70 and the core polyprotein are represented on the cell surface as glycoproteins, as evidenced by incorporation of [3H]glucosamine into their structure and the binding of these proteins to lectins. The glycosylated core polyprotein exists in at least two serologically distinguishable forms: the 95,000-dalton polyprotein reacts with antisera prepared against the viral proteins p30, p12, and p10, whereas the 85,000-dalton polyprotein reacts with antisera prepared against the viral proteins p30 and p12, but not p10. Additional heterogeneity in these cell surface polyproteins has been observed wtih leukemias induced by exogenous leukemia viruses. Spontaneous leukemia cells of AKR mice invariably express gp70 and the core polyprotein on their cell surface; normal thymocytes of young AKR mice express gp70, but not the core polyprotein on their surface.
CubeSat Lunar Mission Using a Miniature Ion Thruster (2011)

The feasibility of CubeSats utilizing the Miniature Xenon Ion (MiXI) thruster for lunar missions is the focus of this investigation. The successful heritage, simplicity, and low cost of CubeSats make them attractive candidates for scientific missions to the Moon. This investigation presents the first-order design process for developing a lunar mission CubeSat. The results from this process are then applied to a 3U CubeSat equipped with a MiXI thruster and specifically designed to reach the lunar surface from a low Earth orbit. The small, 3cm diameter MiXI thruster utilized is capable of producing 0.1–1.553mN of thrust with a specific impulse of over 3000s and is projected to be capable of generating over
Synthesis and Crystallographic Study of Homeotypic LiVPO4F and LiVPO4O (2012)

LiVPO4F stands as an attractive positive electrode material for the next generation of Li-ion batteries to power electric and hybrid electric vehicles and is homeotypic to LiVIVPO4O with a Tavorite-type crystal structure. We report here on the full comparative structural determination of the crystal structures of LiVPO4F and LiVPO4O, thanks to X-ray and neutron diffraction data. Chains of distorted octahedra [VO4X2] (X = F, O) are connected through PO4 tetrahedra forming 3D frameworks with different types of tunnels. ***F***V***F*** sequences are encountered in LiVIIIPO4F with homogeneous V***F distances along the chains whereas successive short and long V***O distances characteristic of vanadyl bonds are observed in LiVIVPO4O. Combining chemical analyses, magnetic measurements, and X-ray and neutron diffraction, it was possible to propose optimized synthesis routes with a controlled high purity for the samples thus formed, as well as to fully describe their structure up to the localization of the lithium ions in five oxygen (fluorine) coordinated environments. LiVPO4F and LiVPO4O are electrochemically active versus lithium insertion or extraction, showing complex and, for one of them, uncommon redox processes. In particular, very distinct values are observed for the same V4+/V3+ redox couple in LiVIIIPO4F and LiVIVPO4O: 4.26 V vs Li0 upon Li+ extraction from LiVIIIPO4F versus on average 2.20 V vs Li0 upon Li+ insertion into LiVIVPO4O. These results highlight that in these Tavorite-type vanadium compounds the Vn+/V(n-1)+ redox couples can be tuned over a wide range of values vs Li0.
Biochemical characterization of the O-linked glycosylation pathway in Neisseria gonorrhoeae responsible for biosynthesis of protein glycans containing N,N'-diacetylbacillosamine. (2011)

The O-linked protein glycosylation pathway in Neisseria gonorrhoeae is responsible for the synthesis of a complex oligosaccharide on undecaprenyl diphosphate and subsequent en bloc transfer of the glycan to serine residues of select periplasmic proteins. Protein glycosylation (pgl) genes have been annotated on the basis of bioinformatics and top-down mass spectrometry analysis of protein modifications in pgl-null strains [Aas, F. E., et al. (2007) Mol. Microbiol. 65, 607-624; Vik, A., et al. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 4447-4452], but relatively little biochemical analysis has been performed to date. In this report, we present the expression, purification, and functional characterization of seven Pgl enzymes. Specifically, the enzymes studied are responsible for synthesis of an uncommon uridine diphosphate (UDP)-sugar (PglD, PglC, and PglB-acetyltransferase domain), glycan assembly (PglB-phospho-glycosyltransferase domain, PglA, PglE, and PglH), and final oligosaccharide transfer (PglO). UDP-2,4-diacetamido-2,4,6-trideoxy-α-d-hexose (DATDH), which is the first sugar in glycan biosynthesis, was produced enzymatically, and the stereochemistry was assigned as uridine diphosphate N'-diacetylbacillosamine (UDP-diNAcBac) by nuclear magnetic resonance characterization. In addition, the substrate specificities of the phospho-glycosyltransferase, glycosyltransferases, and oligosaccharyltransferase (OTase) were analyzed in vitro, and in most cases, these enzymes exhibited strong preferences for the native substrates relative to closely related glycans. In particular, PglO, the O-linked OTase, and PglB(Cj), the N-linked OTase from Campylobacter jejuni, preferred the native N. gonorrhoeae and C. jejuni substrates, respectively. This study represents the first comprehensive biochemical characterization of this important O-linked glycosylation pathway and provides the basis for further investigations of these enzymes as antibacterial targets.
Novel Anionic Annelation Tactics for Construction of Fused Heteroaromatic Frameworks. 1. Synthesis of 4-Substituted Pyrazolo[4,3-c]quinolines, 9-Substituted Pyrazolo[3,4-c]quinolines, and 1,4-Dihydrochromeno[4,3-c]pyrazoles (2001)

4-Substituted pyrazolo[4,3-c]quinolines 4a-i and 6a-b were prepared from pyrazole 3 whereas 9-substituted pyrazolo[3,4-c]quinolines 9a-d and 17 were prepared from pyrazole 13 utilizing anionic annelation techniques. 1,4-dihydrochromeno[4,3-c]pyrazoles 7a-c were accessed from pyrazole 3, extending the method for the synthesis of 4a-i.
Long-range charge carrier mobility in metal halide perovskite thin-films and single crystals via transient photo-conductivity (2022)

Charge carrier mobility is a fundamental property of semiconductor materials that governs many electronic device characteristics. For metal halide perovskites, a wide range of charge carrier mobilities have been reported using different techniques. Mobilities are often estimated via transient methods assuming an initial charge carrier population after pulsed photoexcitation and measurement of photoconductivity via non-contact or contact techniques. For nanosecond to millisecond transient methods, early-time recombination and exciton-to-free-carrier ratio hinder accurate determination of free-carrier population after photoexcitation. By considering both effects, we estimate long-range charge carrier mobilities over a wide range of photoexcitation densities via transient photoconductivity measurements. We determine long-range mobilities for FA<sub>0.83</sub>Cs<sub>0.17</sub>Pb(I<sub>0.9</sub>Br<sub>0.1</sub>)<sub>3</sub>, (FA<sub>0.83</sub>MA<sub>0.17</sub>)<sub>0.95</sub>Cs<sub>0.05</sub>Pb(I<sub>0.9</sub>Br<sub>0.1</sub>)<sub>3</sub> and CH<sub>3</sub>NH<sub>3</sub>PbI<sub>3-x</sub>Cl<sub>x</sub> polycrystalline films in the range of 0.3 to 6.7 cm<sup>2</sup> V<sup>-1</sup> s<sup>-1</sup>. We demonstrate how our data-processing technique can also reveal more precise mobility estimates from non-contact time-resolved microwave conductivity measurements. Importantly, our results indicate that the processing of polycrystalline films significantly affects their long-range mobility.