gebhart/patrepeval huggingface dataset:
A high-resistivity SiGe BiCMOS technology for WiFi RF front-end-IC solutions (2013)

We present for the first time a novel high resistivity bulk SiGe BiCMOS technology that has been optimized for a WiFi RF front-end-IC (FEIC) integration. A nominally 1000 Ohm-cm p-type silicon substrate is utilized to integrate several SiGe HBTs for power amplifiers (PAs), a SiGe HBT low-noise amplifier (LNA), and isolated nFET RF switch device. Process elements include trench isolation for low-loss passives and reduced parasitic coupling, and a lower-resistivity region for the FETs to minimize changes to the circuit library.
Power and Direction of Transmission Estimation for a Directive Source: Identifiability Analysis and Estimation Algorithm (2016)

International audience
Trustworthy computing in a multi-core system using distributed scheduling (2010)

Hardware Trust is an emerging problem in semiconductor integrated circuit (IC) security due to widespread outsourcing and the stealthy nature of hardware Trojans. Conventional post-manufacturing testing, test generation algorithms and test coverage metrics cannot be readily extended to hardware Trojan detection. As a result there is a need to develop approaches that will ensure trusted in-field operation of ICs, and more generally trust in computing. We present a distributed software scheduling prototype, TADS (Trojan Aware Distributed Scheduling), to achieve a Trojan-activation tolerant trustworthy computing system in a multi-core processor potentially containing hardware Trojans. TADS is designed to be transparent to applications and can run on general purpose multicore PEs without modifications to the operating system or underlying hardware. TADS can, with high confidence, continue to correctly execute its specified queue of job subtasks in the presence of hardware Trojans in the multi-core PEs while learning the individual trustworthiness of the individual PEs. Specially crafted self-checking subtasks called bounty hunters are introduced to accelerate PE trust learning. Also, by learning and maintaining individual PE trustworthiness, the scheduler is able to achieve Trojan containment by scheduling subsequent job subtasks to PEs with high learned trust.
Using Preprints for Journal Clubs (2018)

Journal clubs are important mechanisms for teaching how to approach the scientific literature critically and for disseminating findings. Papers from high-impact journals often dominate journal club selections, a practice that reinforces the unscientific emphasis of placing high value on publishing venue rather than scientific content and critical analysis of the publications. We suggest improving journal clubs by including preprints rather than focusing completely on published papers. This change in practice might benefit the scientific enterprise in numerous ways, including by providing direct criticisms to preprint authors before publication, deemphasizing publishing venue, teaching students the art of reviewing papers, and making journal clubs more current by discussing unpublished data.
From Simple Ligands to Complex Structures: Structural Diversity of Silver(I) Complexes Bearing Tetradentate (alkylenebimpy) NHC Ligands (2015)

The synthesis of five new silver(I) NHC complexes, bearing alkylenebimpy ligands with bridge lengths ranging from ethylene to hexylene is described. Their solid-state structures exhibit an unforeseen variety, including infinite strands of Ag3 units within a helically wound ligand environment. The very first infinite chain of almost linear Ag3 units within a cage of helically wound ligand molecules is described. All complexes are spectroscopically characterized and emit polychromatic blue light (420 nm ≤ λ ≤ 510 nm) after laser excitation at λ = 337 nm. This latter behavior might lead to applications in the field of organic light-emitting diodes.
A ±4-A High-Side Current Sensor With 0.9% Gain Error From −40 °C to 85 °C Using an Analog Temperature Compensation Technique (2018)

This paper presents a fully integrated shunt-based current sensor that supports a 25-V input common-mode range while operating from a single 1.5-V supply. It uses a high-voltage beyond-the-rails ADC to directly digitize the voltage across an on-chip shunt resistor. To compensate for the shunt's large temperature coefficient of resistance (~0.335%/°C), the ADC employs a proportional-to-absolute-temperature voltage reference. This analog compensation scheme obviates the need for the explicit temperature sensor and calibration logic required by digital compensation schemes. The sensor achieves 1.5-V noise over a 2-ms conversion time while drawing only 10.9 μA from a 1.5-V supply. Over a ±4-A range, and after a one-point trim, the sensor exhibits a 0.9% (maximum) gain error from -40 °C to 85 °C and a 0.05% gain error at room temperature.
Synthesis, Characterization, and Activity of Hydroxymethylnitrofurazone Nanocrystals against Trypanosoma cruzi and Leishmania spp. (2022)

Hydroxymethylnitrofurazone (NFOH) is a prodrug of nitrofurazone devoid of mutagenic toxicity, with in vitro and in vivo activity against Trypanosoma cruzi (T. cruzi) and in vitro activity against Leishmania. In this study, we aimed to increase the solubility of NFOH to improve its efficacy against T. cruzi (Chagas disease) and Leishmania species (Leishmaniasis) highly. Two formulations of NFOH nanocrystals (NFOH-F1 and NFOH-F2) were prepared and characterized by determining their particle sizes, size distribution, morphologies, crystal properties, and anti-trypanosomatid activities. Furthermore, cytotoxicity assays were performed. The results showed that the optimized particle size of 108.2 ± 0.8 nm (NFOH-F1) and 132.4 ± 2.3 nm (NFOH-F2) increased the saturation solubility and dissolution rate of the nanocrystals. These formulations exhibited moderate anti-Leishmania effects (Leishmania amazonensis) in vitro and potent in vitro activity against T. cruzi parasites (Y strain). Moreover, both formulations could reduce parasitemia (around 89–95% during the parasitemic peak) in a short animal model trial (Y strain from T. cruzi). These results suggested that the increased water solubility of the NFOH nanocrystals improved their activity against Chagas disease in both in vitro and in vivo assays.
3D Structural Transition of the Electrodeposited and Electrochemically Dissolved Li Metal onto an Ultramicroelectrode (2020)

The dendrite growth of Li metal is a very severe problem for a Li metal anode used in rechargeable batteries. In this study, an ultramicroelectrode (UME) was adopted to understand the morphological variation of electrodeposited Li metal. Scanning electron microscopy (SEM) coupled with windowless electron dispersive spectroscopy (EDS) and cryo-orthogonal focused ion beam system (FIB) was utilized to observe not only the surface morphology but also the three-dimensional (3D) structure of the electrodeposited and electrochemically dissolved Li metal. The electrodeposited Li metal from the LiPF6-based electrolyte forms a very uniform column structure. The fluoride-containing solid electrolyte interphase (SEI) layer plays an important role in determining the morphological variation of the dendrite. Furthermore, the fluoride-rich SEI layer shell remains on the UME without collapse after the first cycle. The ultramicroelectrode is a very useful research platform, particularly, for studying drastic dendrite growth and electrochemical dissolution on the Li metal anode.
Effect of low SNR on visual image quality (2015)

The effect of noise on image quality is investigated using human evaluations of a set of images with a wide range of noise and blur levels. Quality is quantified in terms of the smallest contrast feature that can be reliably identified in a test pattern which can be equated to an effective visual resolution. It is found that the image starts to degrade as SNR falls below 50 and below 10 resolution becomes primarily determined by SNR and is insensitive to blur level. The visual information fidelity metric is shown to accurately model the human response.
Promising Effects of Neurorestorative Diets on Motor, Cognitive, and Gastrointestinal Dysfunction after Symptom Development in a Mouse Model of Parkinson's Disease (2017)

Parkinson's disease (PD) is characterized by the progressive degeneration of dopaminergic nigrostriatal neurons, with reductions in the function and amount of dopaminergic synapses. Therefore, synapse loss and membrane-related pathology provide relevant targets for interventions in PD. We previously showed the beneficial preventive effects of a dietary intervention containing uridine and DHA, two precursors for membrane synthesis, in the intrastriatal rotenone model for PD. Here, we examined the therapeutic potential of the same dietary intervention on motor, cognitive, and gastrointestinal symptoms. In addition, we tested the effects of an extended nutritional formula based on the same precursors plus other nutrients that increase membrane phospholipid synthesis as well as prebiotic fibers. C57BL/6J mice received a unilateral rotenone injection in the striatum. Dietary interventions started 28 days after surgery, when motor-symptoms had developed. Readout parameters included behavioral tasks measuring motor function and spatial memory as well as intestinal function and histological examination of brain and gut to assess PD-like pathology. Our results show that rotenone-induced motor and non-motor problems were partially alleviated by the therapeutic dietary interventions providing uridine and DHA. The extended nutritional intervention containing both precursors and other nutrients that increase phospholipid synthesis as well as prebiotic fibers was more effective in normalizing rotenone-induced motor and non-motor abnormalities. The latter diet also restored striatal DAT levels, indicating its neurorestorative properties. This is the first study demonstrating beneficial effects of specific dietary interventions, given after full development of symptoms, on a broad spectrum of motor and non-motor symptoms in a mouse model for PD.
[Rh(.eta.4-((.eta.5-C5H4)OCH2CH2P(C6H5)2)2Fe)]BF4: An Olefin Hydrogenation Catalyst and the First Rhodium(I) cis-Phosphine-cis-Ether Complex Characterized by Single-Crystal X-ray Diffraction Methods (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXT[Rh(.eta.4-((.eta.5-C5H4)OCH2CH2P(C6H5)2)2Fe)]BF4: An Olefin Hydrogenation Catalyst and the First Rhodium(I) cis-Phosphine-cis-Ether Complex Characterized by Single-Crystal X-ray Diffraction MethodsAlan M. Allgeier, Elizabeth T. Singewald, Chad A. Mirkin, and Charlotte L. SternCite this: Organometallics 1994, 13, 8, 2928–2930Publication Date (Print):August 1, 1994Publication History Published online1 May 2002Published inissue 1 August 1994https://doi.org/10.1021/om00020a005RIGHTS & PERMISSIONSArticle Views214Altmetric-Citations31LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (339 KB) Get e-AlertsSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Figure S5 from Single and Dual Targeting of Mutant EGFR with an Allosteric Inhibitor (2023)

&lt;p&gt;The combination treatment of JBJ-04-125-02 and osimertinib do not result in any toxicity issues associated with weight loss but osimertinib at clinically relevant dose (25 mg/kg) is too potent to exhibit additive effect when combined with JBJ-04-125-02.&lt;/p&gt;
Proposal of a new data format for multibeam mask writer with curve expression (2019)

International audience
Sequential assignments and secondary structure of the RNA‐binding transcriptional regulator NusB1 (1997)

The NusB protein is involved in transcriptional regulation in bacteriophage lambda. NusB binds to the RNA form of the nut site and along with N, NusA, NusE and NusG, stabilizes the RNA polymerase transcription complex and allows stable, persistent antitermination. NusB contains a 10 residue Arg-rich RNA-binding motif (ARM) at the N-terminus but is not sequentially homologous to any other proteins. In contrast to other known ARM-containing proteins, NusB forms a stable structure in solution in the absence of RNA. NMR spectroscopy was used to determine that NusB contains six alpha-helices: R10-Q21, 127-F34, V45-L65, Q79-S93, Y100-F114 and D118-L127. The structure of NusB makes it a member of a newly emerging class of alpha-helical RNA-binding proteins.
Optical Stress-sensing Alumina Nanocomposite Coatings for Aerospace Structures (2014)

Alpha alumina (α-Al2O3) nanocomposites have a multi-functional stress sensing ability via their photoluminescence (PL) spectral peak shifts defined by Piezospectroscopic (PS) relationships. This has prompted the development of α-Al2O3 nanocomposite coatings to enable real-time stress measurements and damage assessment of structures with the potential for unparalleled spatial resolution and sensitivity. Here, two types of stress-sensing coatings were evaluated, including an atmospheric plasma spray (APS) coating on metallic substrates and an epoxy nanocomposite coating on a composite substrate. The stress sensitivity of the APS coating, represented by the slope of the peak shifts against stress or PS coefficient, varied inversely with the thickness of the substrates between 3.2 and 1.7 cm-1=GPa. These values decreased by more than 50% after tensile cycling for all substrate thicknesses due to microstructural damage in the APS coating indicating the need for repeatability and durability studies. The epoxy nanocomposite coating successfully captured the stress gradients associated with an open hole tension (OHT) composite substrate revealing damage initiation at 77% of failure load, earlier than visual appearance of a surface crack (93%). The findings validate the successful development of quantitative and multiscale spatial resolution stress-sensing coatings, capable of detecting subsurface damage of composite structures, that will take structural testing and integrity monitoring to the next level.
Real-time decision making in multimodal face-to-face communication (1998)

This paper describes an architecture and mechanism for simulating real-time decision making as observed in full-duplex, multimodal face-to-face interaction between humans. The work bridges between multimodal perception and multimodal action generation and allows flexible implementation of multimodal, fullduplex, conversational characters. It is part of a broad computational model of psychosocial dialogue skills called Ymir. The architecture has been tested with a prototype humanoid, Gandalf [34][35]. Gandalf can engage in taskoriented dialogue with a person and has been shown capable of fluid turn-taking and multimodal interaction [40]. The primary focus in this paper is the real-time decision-making (action selection) mechanism of Ymir and its relation to the multimodal perception and motor control systems. 1.1 Keywords Real-time decision making, agent architectures, multimodal, faceto-face communication 2.
An animal-to-human scaling law for blast-induced traumatic brain injury risk assessment (2014)

Despite recent efforts to understand blast effects on the human brain, there are still no widely accepted injury criteria for humans. Recent animal studies have resulted in important advances in the understanding of brain injury due to intense dynamic loads. However, the applicability of animal brain injury results to humans remains uncertain. Here, we use advanced computational models to derive a scaling law relating blast wave intensity to the mechanical response of brain tissue across species. Detailed simulations of blast effects on the brain are conducted for different mammals using image-based biofidelic models. The intensity of the stress waves computed for different external blast conditions is compared across species. It is found that mass scaling, which successfully estimates blast tolerance of the thorax, fails to capture the brain mechanical response to blast across mammals. Instead, we show that an appropriate scaling variable must account for the mass of protective tissues relative to the brain, as well as their acoustic impedance. Peak stresses transmitted to the brain tissue by the blast are then shown to be a power function of the scaling parameter for a range of blast conditions relevant to TBI. In particular, it is found that human brain vulnerability to blast is higher than for any other mammalian species, which is in distinct contrast to previously proposed scaling laws based on body or brain mass. An application of the scaling law to recent experiments on rabbits furnishes the first physics-based injury estimate for blast-induced TBI in humans.
Absence of GDF5 does not interfere with LPS Toll-like receptor signaling. (2009)

Absence of Gdf5 appears not to affect the LPS response. Mice with a reduced expression of Gdf5 can be used in disease models which are dependent on LPS boost.
Phenanthro[9,10-d]triazole and imidazole derivatives: high triplet energy host materials for blue phosphorescent organic light emitting devices (2019)

A class of wide bandgap host materials is introduced as an alternative to carbazole-based hosts to enhance the efficiency and transport properties of organic light emitting diodes (OLEDs).
ChemInform Abstract: MATRIX‐ISOLATION STUDIES BY ELECTRONIC SPECTROSCOPY OF GROUP IIIA METAL‐WATER PHOTOCHEMISTRY (1983)

Abstract Die Elektronenstrukturen der Zwischenprodukte der Hydratationsreaktion von Metallatomen der Gruppe IIIA (M...OH 2 ‐Addukte) sowie ihrer photolytischen Folgeprodukte HMOH, MOH und M0 mit M: Al, Ga, In werden mitgeteilt.
Increased brightness by light recirculation through an LED source (2008)

LED light sources are finding ever increasing application in illumination. LEDs have many advantages, such as high efficiency, long life, compactness, directional light emission, mechanical resistance, low-temperature operation, light color control and low UV or IR emissions. These and other advantages make them very well suited for general illumination applications as well as flashlights, car headlights, backlights, or frontlights. In most applications, LEDs are combined with optics to direct their light output. Brighter LEDs have a smaller emission area and, therefore, may be coupled to smaller optics. This is very important in many applications where compactness is crucial, particularly automotive headlamps. When LED brightness is insufficient, it can be augmented by recirculating part of the emitted light back to the LED's emitting surface. This increase in brightness comes at the expense of a reduced flux-emission. As an example, the brightness of an LED with a diffuse reflectivity of 70% may be increased by nearly that much if it is coupled to a high-efficiency recirculating optic. Such augmentation, however, comes at the expense of a flux reduction, as much as 50%. Several optical geometries are explored in this paper to achieve that recirculation together with raytracing results using on a simple model of an LED. Also a number of optical architectures will be shown that escape the classical nonimaging etendue limit associated with traditional optics.
Negative regulation of immunoglobulin kappa light-chain gene transcription by a short sequence homologous to the murine B1 repetitive element. (1993)

B-cell-specific expression of the immunoglobulin kappa light-chain (Ig kappa) gene is in part accomplished by negative regulatory influences. Here we describe a new negatively acting element (termed kappa NE) immediately upstream of the NF-kappa B-binding site in the Ig kappa intronic enhancer. The 27-bp kappa NE sequence is conserved in the corresponding positions in the rabbit and human Ig kappa genes, and the human kappa NE homolog was shown to have a similar negative regulatory activity. Data base searches using the mouse kappa NE sequence revealed a striking homology to murine B1 repetitive sequences. A sequence homologous to kappa NE and B1 was also noted in a previously identified silencer element in the murine T-cell receptor alpha locus. The homologous T-cell receptor alpha locus sequence, but notably not a corresponding 27-bp B1 consensus sequence, showed a negative regulatory potential similar to that of kappa NE. The negative effect of kappa NE by itself was not cell type specific but became so when paired with its 5'-flanking sequence in the Ig kappa enhancer. A short (30-bp) fragment upstream of kappa NE (termed kappa BS) was found to be necessary and sufficient for abolishing the negative effect of kappa NE in B cells. Point mutations in a T-rich motif within the kappa BS sequence allowed the transcriptional repression by kappa NE to be evident in B cells as well as other cells. As suggested by this cell-independent negative activity, proteins binding to the mouse and human kappa NE sequences were identified in all cell types tested.
Gas Holdup Imaging Identifies Complex Gas-Liquid Flow Regimes and Introduces a New Velocity Measurement in a Long, Cased Hole, Horizontal, Production Well (2003)

Abstract Gas holdup probes run in a producing horizontal well on the Norwegian continental shelf are used to identify downhole flow regimes and compute the velocity of gas in intermittent flow. The observed flow regimes are compared with the predictions of a number of gas-liquid flow correlations. The theory and quality of velocity correlations are discussed.
Supplementary Figure 1 from 6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells (2023)

Supplementary Figure 1 from 6-Bromoindirubin-3′-Oxime Inhibits JAK/STAT3 Signaling and Induces Apoptosis of Human Melanoma Cells
Advanced 1.1um pixel CMOS image sensor with 3D stacked architecture (2014)

This paper demonstrates an advanced 1.1um pixel backside illuminated CMOS image sensor with a 3D stacked architecture. The carrier wafer in conventional BSI is replaced by ASIC wafer, which contains a part of periphery circuit and is connected to the sensor wafer through bonding technology. With proper layout design and process improvement, the impact of 3D connection (Through Via, TV) on the sensor performance can be significantly minimized. In addition, for the first time, the degradation of stacked pixel performance during the folded circuit operation under sensor array is found and improved. The final stacked sensor exhibits the comparable pixel performances to conventional BSI. Furthermore, stacked architecture provides the opportunity to enhance sensor performance by the separate process tuning for sensor wafers (without any effect on ASIC wafers), leading to a further improvement of dark performance.
Towards Secure Two-Party Computation from the Wire-Tap Channel (2013)

We introduce a new protocol for secure two-party computation of linear functions in the semi-honest model, based on coding techniques. We first establish a parallel between the second version of the wire-tap channel model and secure two-party computation. This leads us to our protocol, that combines linear coset coding and oblivious transfer techniques. Our construction requires the use of binary intersecting codes or $q$-ary minimal codes, which are also studied in this paper.