gebhart/patrepeval huggingface dataset:
Convergence and tracking analysis of the &#x03B5;-NSRLMF algorithm (2013)

In this work, the convergence and tracking behavior of the ε-normalized sign regressor least mean fourth (NSRLMF) algorithm are analyzed in the presence of white and correlated Gaussian data. Furthermore, the stability bound on the step-size of the ε-NSRLMF algorithm to ensure convergence in the mean, which also leads us to the mean convergence of the ε-normalized sign regressor least mean mixed-norm (NSRLMMN) algorithm is derived. Finally, simulation results are conducted to confirm the validity and performance of the proposed adaptive algorithm for both white and correlated Gaussian regressors.
Adaptive perturb and observe algorithm for photovoltaic maximum power point tracking (2010)

The optimisation of energy generation in a photovoltaic (PV) system is necessary to let the PV cells operate at the maximum power point (MPP) corresponding to the maximum efficiency. Since the MPP varies, based on the irradiation and cell temperature, appropriate algorithms must be utilised to track the MPP. This is known as maximum power point tracking (MPPT). Different MPPT algorithms, each with its own specific performance, have been proposed in the literature. A so-called perturb and observe (P&amp;O) method is considered here. This method is widely diffused because of its low-cost and ease of implementation. When atmospheric conditions are constant or change slowly, the P&amp;O method oscillates close to MPP. However, when these change rapidly, this method fails to track MPP and gives rise to a waste of part of the available energy. An adaptive P&amp;O method is proposed in this study that has faster dynamics and improved stability compared to the traditional P&amp;O. The MPPT algorithm was set up and validated by means of numerical simulations and experimental tests, confirming the effectiveness of the method.
Supplementary Figure 2 from Global Evaluation of Eph Receptors and Ephrins in Lung Adenocarcinomas Identifies EphA4 as an Inhibitor of Cell Migration and Invasion (2023)

&lt;p&gt;PDF file, 37K, Ephs and eprins in vitro.&lt;/p&gt;
In situ TEM Observation of the Nucleation and Growth of Metal Oxide Nanoparticles on Graphene (2013)

Extended abstract of a paper presented at Microscopy and Microanalysis 2013 in Indianapolis, Indiana, USA, August 4 – August 8, 2013.
The Fourth Dimension (2010)

adiofrequency ablation is now a cornerstone in the management of ventricular tachycardia (VT). VT ablation plays a palliative role in decreasing shocks and improving the quality of life in patients with structural heart disease and is often curative in treating VT in patients with normal hearts. 1,2 When compared with other types of ablation, however, VT procedures have lower success rates, have a propensity for complications, and are technically challenging. A recognized cause for difficulty is the need to address the 3-dimensional pathological substrate (endocardial, midmyocardial, epicardial). At present, combined endocardial and epicardial approaches 3 have largely addressed this problem and, along with a larger electrode and irrigation-based ablation, may allow success for the midmyocardial substrate as well.
High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo (2009)

The RelA/p65 inhibitory effects of SAHA and VPA in vitro and the close relationship of class I HDACs and RelA/p65 in vivo suggest that treatment with HDIs could serve as a promising approach to suppress NF-kappaB activity which in turn may lead to enhanced apoptosis and chemosensitization of pancreatic cancers.
The frictional characteristics of single-phase-drive type USM (2004)

In this paper we analyze the mechanical characteristics of the single-phase-drive type ultrasonic motors. Though single-phase-drive type ultrasonic motors (USMs) has many merits against the multi-phase-drive type USMs, the research of them are not popular and the design method is not established yet. We simulated the static driving characteristics of the single-phase-drive type USM and cleared up the relationship between design parameters and T-N curve, output power and frictional efficiency. Finally we show the adequacy of the simulations by conducting the driving tests.
High-Power and Widely-Tunable Evanescent-Mode Cavity-Backed Slot Antenna (2018)

A new high-power and widely-tunable cavity-backed slot antenna is introduced and experimentally investigated in this work. The proposed antenna is composed of a tunable evanescent-mode cavity resonator with a radiating slot on its back wall. The antenna tuning is based on a piezoelectric actuator which changes the resonator gap size in the range of 15-170 μm, Considering minimum return loss of 10 dB, a prototype fabricated antenna was successfully tuned over the frequency range of 1.8-2.6 GHz, representing about 36% tunability. The simulated antenna gain at 2.4 GHz is about 5.4 dBi while the antenna can potentially handle high powers up to 100 W.
Abstract 13235: Reentrant Sources in Persistent AF Are Located in Regions with Specific Spatial Patterns of Fibrosis (2014)

Introduction: Fibrosis is associated with increased risk of persistent atrial fibrillation (psAF), but it remains unknown how the specific distribution of fibrosis determines the preferential locations of atrial reentrant sources (RSs). Hypothesis: We hypothesized that RSs in psAF patients persist in fibrotic regions with distinct spatial characteristics that can be quantitatively assessed. Methods: Late Gadolinium Enhancement LGE-MRI and noninvasive electrocardiographic imaging (ECGI) data were acquired from patients with psAF. Patient specific, biophysically accurate atrial models were developed from images (Fig A). A dynamic pacing protocol was used to induce psAF in models. Locations of persistent RSs in simulations (reentries lasting >2s) were compared to ECGI data to validate each model. Then, at each point in the model atria, we computed local spatial metrics for the volume within a 2.5 mm radius: fibrosis density (proportion of LGE tissue by volume), fibrosis clustering (diffuse or patchy) by Moran’s I, and complexity of fibrosis pattern by Shannon entropy. Results: In all patient-specific models, persistent RS locations were the same as those detected by ECGI (within 2 cm of each other, as in Fig B). At such locations, fibrosis characteristics were distinct from those in the rest of the atria (p 0.6, clustering > 0.8, and complexity > 0.8 occupied only 3.25% of atrial volume (Fig D), suggesting that a limited amount of tissue had the specific fibrosis pattern that favored RS persistence. Conclusion: Persistent RSs in psAF are harbored by fibrotic regions with distinct spatial characteristics. Identifying such regions can help determine the optimal targets for ablation of psAF.
Investigation of TMI in Yb-doped fully-aperiodic large-pitch-fibers using spatially and temporally resolved imaging (2022)

In this work we present investigation of TMI in Yb-doped FA-LPF using spatially and temporally resolved imaging. We present ST-measurements that are clearly describing the system noises and that can be used to optimize amplifier systems in order to mitigate TMI. Comparative TMI measurements between the same FA-LPF in amplifier and laser configuration are also presented. These measurements show similar results with respect to optical efficiencies but large differences with respect to TMI.
Experimental evaluation of guidance and forbidden region virtual fixtures for object telemanipulation (2014)

Telerobotic task performance cannot compare to direct object manipulation with the hands. However, the computer in-the-loop offers the potential to give assistance to a human operator. The present work studies a class of computer assistance functions known as haptic virtual fixtures (VF). The objective is to use practical human trials to discover the ways VFs impact task execution.
Mucus Glycoprotein Content of Human Cholesterol Gallstones (1987)

Cholesterol gallstones were obtained from patients undergoing cholecystectomy and the mucus glycoprotein extracted. The biliary mucus glycoprotein was separated from other contaminants by Sepharose 4B gel filtration and the PAS staining excluded volume used to estimate mucus glycoprotein content of the gallstones. Hexosamine and sialic acid analysis of the glycoprotein indicated it was compositionally similar to the human mucus glycoprotein from bile. The mucus glycoprotein content of the nine stones analysed individually varied between 0.75 and 2.3 mg (a 3-fold variation) (1.27 ± 0.16 mg, x ± SEM), whereas stone weight varied between 0.076 and 5.885 g (a 77-fold variation) (1.27 ± 0.63 g, x ± SEM). When a pool of smaller stones, average weight 47 mg, was extracted, only 1.73 mg of glycoprotein was isolated, an average of 0.01 mg/stone. Analysis of the mucus glycoprotein by gel filtration on Sepharose 2B showed the majority of the glycoprotein was excluded as is the case with the mucus glycoprotein in bile. These results are consistent with biliary mucus glycoprotein being involved in the initial stages of gallstone formation but not in subsequent growth.
TaskSet: A Dataset of Optimization Tasks (2021)

We present TaskSet, a dataset of tasks for use in training and evaluating optimizers. TaskSet is unique in its size and diversity, containing over a thousand tasks ranging from image classification with fully connected or convolutional neural networks, to variational autoencoders, to non-volume preserving flows on a variety of datasets. As an example application of such a dataset we explore meta-learning an ordered list of hyperparameters to try sequentially. By learning this hyperparameter list from data generated using TaskSet we achieve large speedups in sample efficiency over random search. Next we use the diversity of the TaskSet and our method for learning hyperparameter lists to empirically explore the generalization of these lists to new optimization tasks in a variety of settings including ImageNet classification with Resnet50 and LM1B language modeling with transformers. As part of this work we have opensourced code for all tasks, as well as ~29 million training curves for these problems and the corresponding hyperparameters.
Active Control of an Incompressible Axisymmetric Jet Using Flaps and Zero Mass-flux Excitation (2010)

An active flow control method of an axis-symmetric jet is being investigated which, when activated, generates streamwise vortices and thus enhances mixing of the jet flow with the ambient. The perimeter of the jet is equipped with six small flaps deflected away from the stream. Zero mass-flux perturbations are being used to excite the flow. These excitations are introduced in the flow through slots at the base of the flaps. Each of the flaps can be excited independently. In former studies, the shape and angle of a single flap were optimized and the local effect on the jet analyzed. It was shown that the local mixing can be increased. In the current investigations, the effect of an array of six individually controllable flaps on the global jet behavior is addressed. Each of the flaps can be excited in phase or with pre-fixed phase shift. Effects of frequency and amplitude on the flow momentum, streamwise vorticity, circulation and turbulence for a fixed flap deflection angle are part of the investigation. A stereo-PIV setup is being used to acquire complete flow field information. The emphasis is being placed on mapping the development of the trailing vortices in order to quantify the mixing achieved.
Service guarantees for joint scheduling and flow control (2002)

We consider a general mesh network with multiple traffic streams subject to window flow control on a per hop, per stream basis. Scheduling at each server is governed by "service curve" requirements. We establish lower bounds on the window sizes such that each stream receives pre-specified service guarantees.
Computational Fluid Dynamics and Thermal-Hydraulic Analyses of SLIMM Reactor Passive Decay Heat Removal by Natural Circulation of Ambient Air (2016)

The Scalable LIquid Metal–cooled small Modular (SLIMM) reactor generates 10 to 100 MW(thermal) for extended periods without refueling. With the aid of an in-vessel chimney and a Na/Na helically coiled tubes heat exchanger (HEX) in the downcomer, natural circulation of in-vessel liquid sodium cools the SLIMM reactor core during nominal operation and after shutdown. With an unlikely malfunction of the Na/Na HEX, natural circulation of ambient air along the outer surface of the guard vessel wall maintains in-vessel natural circulation of liquid sodium and passively removes the decay heat after reactor shutdown. This paper performs three-dimensional computational fluid dynamics and thermal-hydraulic analyses to obtain preliminary estimates of the rate of decay heat removal by ambient air in case of a malfunction of the in-vessel Na/Na HEX and investigates the effect of using longitudinal metal fins along the guard vessel outer surface. The analyses calculate the contributions of natural convection and thermal radiation to the rate of decay heat removal by ambient air. For the same sodium temperatures in the reactor vessel downcomer as during steady-state nominal operation at 100 MW(thermal), the decay heat removal rate by ambient air without metal fins is ~1.0 MW(thermal), increasing by 26% to 1.26 MW(thermal) with metal fins. The contributions of natural convection and thermal radiation to the rate of decay heat removal are 58% and 42% without metal fins and 70% and 30% with metal fins, respectively. Extending the metal fins an additional 5 m and doubling the axial thermal conductivity increase the rate of the decay heat removal only slightly, to 1.28 MW(thermal).
Communication Analysis through Visual Analytics: Current Practices, Challenges, and New Frontiers (2022)

The automated analysis of digital human communication data often focuses on specific aspects such as content or network structure in isolation. This can provide limited perspectives while making cross-methodological analyses in domains like investigative journalism difficult. Communication research in psychology and the digital humanities instead stresses the importance of a holistic approach to overcome these limiting factors. In this work, we conduct an extensive survey on the properties of over forty semi-automated communication analysis systems and investigate how they cover concepts described in theoretical communication research. From these investigations, we derive a design space and contribute a conceptual framework based on communication research, technical considerations, and the surveyed approaches. The framework describes the systems’ properties, capabilities, and composition through a wide range of criteria organized in the dimensions (1) Data, (2) Processing and Models, (3) Visual Interface, and (4) Knowledge Generation. These criteria enable a formalization of digital communication analysis through visual analytics, which, we argue, is uniquely suited for this task by tackling automation complexity while leveraging domain knowledge. With our framework, we identify shortcomings and research challenges, such as group communication dynamics, trust and privacy considerations, and holistic approaches. Simultaneously, our framework supports the evaluation of systems and promotes the mutual exchange between researchers through a structured, common language, laying the foundations for future research on communication analysis.
Electrical, Chemical, and Topological Addressing of Mammalian Cells With Microfabricated Systems (1999)

This communication describes our work in electrical, topological, and chemical micromodification of surfaces to modulate cellular form and function. We have addressed the surface physico-chemico-mechano properties of cell culture substrates that play a role in modulating cellular behavior. Single factorial model systems have been built using techniques adapted from microlithography. The tools and techniques of microfabrication, if harnessed and used correctly, can be enabling in elucidating the underlying principles and fundamental forces driving the cell-substrate interface. Additionally, the long-term practical applications of microfabrication in medicine and biomaterial/tissue engineering lie in enabling "communication" with living cells/tissues at the cellular and subcellular levels.
A Methodology for Reliability Enhancement of Nanometer-Scale Digital Systems Based on A-Priori Functional Fault-Tolerance Analysis (2005)

This paper presents a new approach for monitoring and estimating device reliability of nanometer-scale devices prior to fabrication. A four-layer architecture exhibiting a large immunity to permanent as well as random failures is used. A complete tool for a-priori functional fault tolerance analysis was developed. It is a statistical Monte Carlo based tool that induces different failure models, and does subsequent evaluation of system reliability under realistic constraints. A structured fault modeling architecture is also proposed, which is together with the tool a part of the new design method representing a compatible improvement of existing IC design methodologies. 1.
Real time hardware neural spike amplitude extraction (2005)

A novel algorithm for population spike (PS) amplitude extraction suitable for real time hardware processing was developed. The extraction method was implemented digitally and experimentally tested on a field programmable gate array (FPGA) device using 16-bit quantization. The accuracy of the implementation was tested using PS signals recorded from hippocampal slices. The PS response of the dentate gyrus granule cells were generated in a multi-electrode array (MEA) setup. Spike amplitudes extracted in real time by the hardware were compared with values resulting from floating-point computation in software. Results showed successful implementation of hardware algorithm with average normalized mean square error (NMSE) less than 2%.
PF614 PATIENT‐REPORTED OUTCOMES FROM THE INNOVATE™ STUDY: RESULTS OF IBRUTINIB‐RITUXIMAB IN WALDENSTRÖM MACROGLOBULINEMIA (WM) (2019)

Background: Anemia and fatigue can impair quality of life in patients (pts) with WM and are common reasons for the initiation of WM treatment. Ibrutinib, a first‐in‐class, once‐daily inhibitor of BTK, is approved in the EU for the treatment of WM after ≥1 prior therapy or as first‐line therapy in pts unsuitable for chemoimmunotherapy. In the US, ibrutinib is approved for the treatment of WM as single agent or in combination with rituximab. Single‐agent ibrutinib has been shown to induce clinically meaningful improvements in pt‐reported outcomes (PROs) in pts with rituximab‐refractory WM (Trotman, EHA 2017). In the primary analysis of the phase 3 iNNOVATE study, ibrutinib‐rituximab produced higher rates of sustained hemoglobin improvement and meaningful improvements in PROs when compared with placebo‐rituximab (Dimopoulos NEJM 2018). Here, we report a more detailed analysis of PROs from iNNOVATE. Aims: To evaluate data on PROs from the iNNOVATE study to assess pts’ perspectives of the therapeutic benefit of ibrutinib‐rituximab. Methods: Pts with symptomatic WM requiring therapy were randomized to daily 420 mg oral ibrutinib or placebo until progressive disease or unacceptable toxicity. Both arms also received rituximab (375 mg/m 2 /week IV at weeks 1–4 and 17–20). PRO measures evaluated in this analysis included FACIT‐Fatigue (FACIT‐F), FACT‐An total score (TS) and anemia subscale score (AS), and EQ‐5D‐5L (© EuroQol Research Foundation. EQ‐5D™ is a trade mark of the EuroQol Research Foundation) visual analog scale (VAS) and utility score (US). Results: For the 150 randomized pts (75/arm), the most common reasons for initiating treatment were fatigue (61%), constitutional symptoms (32%), and anemia (32%). Baseline PRO scores were comparable in both arms. Overall (median follow‐up, 26.5 months), more pts showed clinically meaningful improvement in FACIT‐F, TS, and AS with ibrutinib‐rituximab than placebo‐rituximab (Table &amp; Figure). The median time to PRO improvement was short (1–2 months) and comparable in both arms. A correlation analysis conducted at week 25 showed that changes in hemoglobin levels correlated with FACIT‐F (Pearson coefficient r = 0.28), TS (r = 0.29), and AS (r = 0.26) in the ibrutinib‐rituximab arm; no meaningful correlations were observed on placebo‐rituximab. Changes in IgM levels correlated with FACIT‐F (r = −0.32), TS (r = −0.33), AS (r = −0.35), and EQ‐VAS (r = −0.26) for ibrutinib‐rituximab and with FACIT‐F (r = 0.29) and TS (r = 0.35) for placebo‐rituximab. Summary/Conclusion: These results show that in pts with WM, clinical response and improvements in anemia with ibrutinib‐rituximab are consistent with more pts showing clinically meaningful improvement in PROs compared with placebo‐rituximab. Changes in IgM correlate with improvements in PROs in pts treated with ibrutinib‐rituximab. image
High-sensitivity intrinsic fiber-optic Fabry–Perot pressure sensor (1996)

A new configuration for a pressure sensor in which the motion of a diaphragm produces strain in a fiber Fabry-Perot interferometer (FFPI) is described. The single-mode fiber containing the interferometer is bonded at one end to the stainless-steel diaphragm. The fiber is also attached beyond the interferometer to the sensor housing in such a manner that it is always under tension and experiences a strain in proportion to the deflection of the diaphragm. An analysis relating the expected interferometer phase change to pressure is presented, and the dynamic response of the FFPI sensor to pressure changes produced by an air pump is in good agreement with that measured with a conventional pressure sensor.
Hyperbranched Poly(ε-caprolactone) Derived from Intrinsically Branched AB2 Macromonomers (1998)

ADVERTISEMENT RETURN TO ISSUEPREVCommunication to the...Communication to the EditorNEXTHyperbranched Poly(ε-caprolactone) Derived from Intrinsically Branched AB2 MacromonomersMikael Trollsås and James L. HedrickView Author Information NSF Center for Polymeric Interfaces and Macromolecular Assemblies (CPIMA), IBM Research Division, Almaden Research Center, 650 Harry Road, San Jose, California 95120-6099 Cite this: Macromolecules 1998, 31, 13, 4390–4395Publication Date (Web):June 13, 1998Publication History Received2 February 1998Revised4 May 1998Published online13 June 1998Published inissue 1 June 1998https://pubs.acs.org/doi/10.1021/ma980151ahttps://doi.org/10.1021/ma980151arapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views793Altmetric-Citations103LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Monomers,Organic polymers,Pharmaceuticals,Polymerization,Polymers Get e-Alerts
No Slackers in Tourniquet Use to Stop Bleeding (2013)

Any slack presence in the strap impaired tourniquet performance. More slack had worse results. Trainers can now instruct tourniquet users with concrete guidance.