gebhart/patrepeval huggingface dataset:
Kirigami-Based Deployable Transcrease Hard Stop Models Usable in Origami Patterns (2019)

Abstract Stopping origami in arbitrary fold states can present a challenge for origami-based design. In this paper two categories of kirigami-based models are presented for stopping the fold motion of individual creases using deployable hard stops. These models are transcrease (across a crease) and deploy from a flat sheet. The first category is planar and has behavior similar to a four-bar linkage. The second category is spherical and behaves like a degree-4 origami vertex. These models are based on the zero-thickness assumption of paper and can be applied to origami patterns made from thin materials, limiting the motion of the base origami pattern through self-interference within the original facets. Model parameters are based on a desired fold or dihedral angle, as well as facet dimensions. Examples show model benefits and limitations.
Template-assisted synthesis of CdS nanocrystal arrays in chemically inhomogeneous pores using a vapor–solid mechanism (2015)

Template of chemically inhomogeneous pores enables one to grow an ordered array of CdS multi-armed nanocrystals free of catalyst.
The Association Between Adjuvant Pain Medication Use and Outcomes Following Pediatric Spinal Fusion (2016)

3.
Absorption, Distribution, Metabolism, and Excretion of Aprocitentan, a Dual Endothelin Receptor Antagonist, in Humans (2021)

Based on these metabolism data, aprocitentan can be concomitantly administered without dose adjustment with drugs that are inhibitors or inducers of any metabolizing enzyme, specifically cytochrome P450 enzymes.
An Insecticidal and Acaricidal Polysulfide Metabolite from the Roots of Petiveria alliacea (1997)

The present study reports on the insecticidal and acaricidal potentials of dibenzyltrisulfide (DBTS) isolated from the roots of Petiveria alliacea L. using thin layer and high performance liquid chromatography. The 96-h LD50 value (μg per tick) obtained for adult Boophilus microplus (Canestrini) topically treated with DBTS was 0·920. The LD50 values obtained for three commercial acaricides dimethoate, lindane and carbaryl were 4·6, 9·3 and 6·9 μg per tick respectively. The IOD50 and IHD50 (concentrations inhibiting egg laying and hatching by 50% respectively) in μg per tick doses for DBTS were 0·22 and 0·24 respectively. The 24-h LD50 dose (μg per insect) obtained for DBTS on adult Cylas formicarius elegantulus (Summer) was 0·193 μg per insect. The vapour from a stock solution of 5 g litre-1 of DBTS was highly toxic to adult Hypothenemus hampei Ferr. inside coffee berries, inflicting 89% mortality within 24 h. © 1997 SCI.
In vivo wireless communication channels (2012)

In this paper we perform signal strength and channel impulse response simulations using an accurate human body model and we investigate the variation in signal loss at different RF frequencies as a function of position around the human body. It was observed that significant variations in received signal strength (RSS) occurred with changing position of the external receive antenna at a fixed distance from the internal antenna. The variations were even more profound at the highest frequency, where just a 5° of movement causes an increase of RSS up to 20 dB. Wideband scattering parameters were also obtained and the channel impulse response was calculated. A greater amount of dispersion through the abdomen has been observed than was expected based on human body geometry.
Synergistic Polymer–Surfactant-Complex Mediated Colloidal Interactions and Deposition (2020)

Total internal reflection microscopy (TIRM) is used to directly, sensitively, and simultaneously measure colloidal interactions, dynamics, and deposition for a broad range of polymer-surfactant compositions. A deposition state diagram containing comprehensive information about particle interactions, trajectories, and deposition behavior is obtained for polymer-surfactant compositions covering four decades in both polymer and surfactant concentrations. Bulk polymer-surfactant phase behavior and surface properties are characterized to provide additional information to interpret mechanisms. Materials investigated include cationic acrylamide-acrylamidopropyltrimonium copolymer (AAC), sodium lauryl ether sulfate (SLES) surfactant, silica colloids, and glass microscope slides. Measured colloid-substrate interaction potentials and deposition behavior show nonmonotonic trends vs polymer-surfactant composition and appear to be synergistic in the sense that they are not easily explained as the superposition of single-component-mediated interactions. Broad findings show that at some compositions polymer-surfactant complexes mediate bridging and depletion attractions that promote colloidal deposition, whereas other compositions produce electrosteric repulsion that deters colloidal deposition. These findings illustrate mechanisms underlying colloid-surface interactions in polymer-surfactant mixtures, which are important to controlling selective colloidal deposition in multicomponent formulation applications.
Analysis of Intermediate Resonant Couplers for High Displacement Inductive Power Transfer (2019)

Inductive power transfer (IPT) is increasingly being investigated for vehicle charging applications due to the galvanic isolation present between the primary and secondary sides and the ease of parking due to its plug-free nature. However, in some applications such as SUVs with high ground clearance it is difficult to provide a cost-effective solution while maintaining low leakage fields. This paper investigates the use of a Circular or Bipolar intermediate resonating coils placed between the ground and the vehicle to increase the vertical displacement over which significant power can be transferred. In this work, circular pads (CP) were used for the ground and vehicle assemblies assumed in the SAEJ2954 standards. Results show that for certain vertical displacements it is possible to transfer power while keeping within the magnetic leakage fields using either of the intermediate pads.
TV holography and image processing in practical use (1991)

Image processing has been used to analyze TV-holographic fringe patterns of deformation and vibrations. Recent results using such image processing algorithms for deformation and vibration measurements are described. It is shown how these techniques has been used on practical objects such as concrete, high-frequency transducers, and underwater transducers.
Adaptive compensation of atmospheric effects with a high-resolution micro-machined deformable mirror (2002)

We present experimental results for the adaptive compensation of atmospheric turbulence effects on a free-space laser communication links at near horizontal propagation paths over 2.5 km and 5 km lengths. A high-resolution micro-machined piston type mirror array (12x12 elements) and a fast beam steering mirror were used in an adaptive optics laser communication system based on the model-free stochastic parallel gradient descent (SPGD) optimization wavefront control technique. Control of the mirror was performed by a VLSI SPGD micro-controller. The experimental results demonstrate the improvement of the receiver performance (fiber coupling efficiency) on a summer day with a refractive index structure constant in the order of <i>C<sub>n</sub><sup>2</sup></i>&ap;10<sup>-14</sup> m<sup>-2/3</sup>.
Cognitive computing: Neuroscience, supercomputing, nanotechnology (2011)

Summary form only given. The word “Robot” means many things. According to some definitions “A robot is a mechanical contraption which can perform tasks on its own, or with guidance. In practice a robot is usually an electromechanical machine which is shown what to do by computer and electronic programming.” And another says “A machine capable of carrying out a complex series of actions automatically, especially one programmable by a computer.” All these definitions lead us to realize that these Robots are not intelligent machines so they seek our instructions to function. The sub category “mobile robots” serve us from domestic applications, exploration and mapping, traffic control systems, aero space applications, flight controlling and in network centric warfare.
Generalized Gilat–Raubenheimer method for density-of-states calculation in photonic crystals (2018)

An efficient numerical algorithm is the key for accurate evaluation of density of states (DOS) in band theory.The Gilat-Raubenheimer (GR) method proposed in 1966 is an efficient linear extrapolation method which was limited in specific lattices.Here, using an affine transformation, we provide a new generalization of the original GR method to any Bravais lattices and show that it is superior to the tetrahedron method and the adaptive Gaussian broadening method.Finally, we apply our generalized GRmethod to compute DOS of various gyroid photonic crystals of topological degeneracies.
Calcitropic Non-ionic Surfactant Lamellar Phases (1996)

The aqueous non-ionic surfactant decaethylene glycol hexadecyl ether (C16EO10), in the presence of CaCl2, forms novel “calcitropic” lamellar liquid-crystal phases. Thin films of these materials display notable structure sensitivity to the hydrophobicity or hydrophilicity of the underlying support. A structure-bonding model of these materials is based upon Ca2+-crown ether-like coordination to the decaethylene glycol head group of one or two of the surfactant molecules. Ca2+ binding of two surfactant head groups, makes possible cis- and trans-conformations for the alkyl tails, resulting in normal and inverted structures with preferences for hydrophilic and hydrophobic surfaces, respectively. The extent of Ca2+ ion clustering in the head group determines the geometrical packing requirements of the surfactant and the overall dimensions of the resulting lamellar liquid-crystal phases. The effect of various phosphate reagents (H3PO4, KH2PO4, K3PO4) on these “calcitropic” liquid-crystal phases has also been investigated. The conditions that favor the deposition of different calcium phosphate solid phases from these “calcitropic” lamellar precursors have been investigated, with a view to their possible use as “controlled release biomaterials” for supplying thin-film and nanocrystalline forms of calcium phosphate for bone restoration, replacement, and augmentation applications. The nontoxic, biocompatible, biodegradable, and inexpensive nature of oligoethylene glycol alkyl ethers is a distinctive advantage for these kinds of endeavors.
Real-time In Vivo Raman Spectroscopy: Technology Development and Clinical Applications in Early Cancer Detection (2013)

We have successfully developed a platform technology for real-time in vivo Raman spectroscopy of human tissues. Spectra can be obtained within 1–2 seconds. Clinical applications have been implemented for skin cancer and lung cancer detection.
Abstract PR02: Mutational analysis of head and neck squamous cell carcinoma stratified by smoking status (2020)

Abstract Smoking has historically been recognized as a negative prognostic factor in head and neck squamous cell carcinoma (HNSCC). This study aimed to assess the mutational differences between heavy smokers (&amp;gt;20 pack-years) and never smokers among the HNSCC patients within The Cancer Genome Atlas (TCGA). Single nucleotide variation (SNV) and copy number aberration (CNA) differences between heavy smokers and never smokers were compared within HPV-positive (n=67) and negative (n=431) TCGA HNSCC cohorts, and the impact of these mutations on survival was assessed. No genes were differentially mutated between smoking and never smoking patients with HPV-positive tumors. By contrast, in HPV-negative tumors, NSD1 and COL1A11 were found to be more frequently mutated in heavy smokers, while CASP8 was more frequently altered in never smokers. HPV-negative patients with NSD1 mutations experienced significantly improved overall survival compared with NSD1 wild-type patients. This improved prognosis was validated in an independent cohort of 77 oral cavity cancers and a meta-analysis that included two additional datasets (688 total patients, hazard ratio for death 0.44, 95% CI 0.30-0.65). NSD1 mutations are more common in HPV-negative heavy smokers and define a cohort with favorable prognosis, and may represent a clinically useful biomarker to guide treatment deintensification for HPV-negative patients. Citation Format: Farhad Ghasemi, Stephenie D. Prokopec, Danielle MacNeil, Neil Mundi, Christopher Howlett, William Stecho, Kevin Fung, John Yoo, Eric Winquist, Steven Gameiro, Axel Sahovaler, Paul Plantinga, Joe S. Mymryk, John W. Barrett, Paul C. Boutros, Anthony C. Nichols. Mutational analysis of head and neck squamous cell carcinoma stratified by smoking status [abstract]. In: Proceedings of the AACR-AHNS Head and Neck Cancer Conference: Optimizing Survival and Quality of Life through Basic, Clinical, and Translational Research; 2019 Apr 29-30; Austin, TX. Philadelphia (PA): AACR; Clin Cancer Res 2020;26(12_Suppl_2):Abstract nr PR02.
Reprogramming Cellular Behavior with RNA Controllers Responsive to Endogenous Proteins (2010)

Synthetic genetic devices that interface with native cellular pathways can be used to change natural networks to implement new forms of control and behavior. The engineering of gene networks has been limited by an inability to interface with native components. We describe a class of RNA control devices that overcome these limitations by coupling increased abundance of particular proteins to targeted gene expression events through the regulation of alternative RNA splicing. We engineered RNA devices that detect signaling through the nuclear factor κB and Wnt signaling pathways in human cells and rewire these pathways to produce new behaviors, thereby linking disease markers to noninvasive sensing and reprogrammed cellular fates. Our work provides a genetic platform that can build programmable sensing-actuation devices enabling autonomous control over cellular behavior.
Enantiomeric disposition of ketorolac in goats following administration of a single intravenous and oral dose (2008)

The purpose of this study was to investigate the stereospecific pharmacokinetics of ketorolac (KT) in goats following a single 2 mg/kg intravenous (i.v.) dose and a single 6 mg/kg oral dose. A stereoselective high pressure liquid chromatography assay was used to quantify ketorolac plasma concentrations. Pharmacokinetic parameters for both stereoisomers were estimated by model independent methods. Following an i.v. dose, the plasma concentration profiles for the stereoisomers were similar with half-lives of 1.05 +/- 0.62 h for R-KT and 1.05 +/- 0.61 h for S-KT. Clearance values for R- and S-KT after an i.v. dose were 0.53 +/- 0.23 and 0.54 +/- 0.23 L.h/kg, respectively. Following an oral dose, the terminal half-lives were longer with values of 34.08 +/- 11.81 and 33.97 +/- 12.19 h for R-KT and S-KT, respectively. The average bioavailability was 133 +/- 23% for R-KT and S-KT, respectively. The longer half-lives and high apparent bioavailability after oral dosing are suggestive of a slow absorption process in the gastrointestinal tract and recycling. The results indicate that interconversion of the stereoisomers of ketorolac is absent in goats. However, studies with individual isomers are needed before any conclusion can be drawn about the lack of bioinversion.
Modeling weak shocks produced by high-intensity focused ultrasound. (2009)

Shock waves of up to 100 MPa may form at the focus of high-intensity focused ultrasound (HIFU) transducers at clinically reported in situ intensities of up to 30,000 W/cm2. The heating due to shocks is sufficient to boil tissue in milliseconds, which dramatically alters the treatment. Quantification of enhanced heating from shocks is therefore critical to treatment planning. In this work, several approaches and temporal grids of different resolutions were used to simulate HIFU fields. Peak positive pressure, which determines the shock amplitude, and thus the heating rate were found to be the most sensitive to the parameters of the numerical scheme. Heating rates calculated in modeling and estimated using weak shock theory from the measured and modeled waveforms were compared. Time to boil measured in tissue phantoms and tissue was used as a metric of the heating efficiency of shocks. It is shown that the bandwidth limitations in the waveform measurements result in underestimation of the heat rates, although boiling onset predicted in modeling agreed well with the experimental data. An experimentally validated numerical model thus can be an effective tool in both laboratory and clinical HIFU setting. [Work is supported by NIH EB007643 and NSBRI SMST01601.]
Freshwater Water-Quality Criteria for Chloride and Guidance for the Revision of the Water-Quality Standard in China (2023)

The chloride in water frequently exceeds the standard; directly quoting foreign water-quality criteria (WQC) or standards will inevitably reduce the scientific value of the water-quality standard (WQS) in China. Additionally, this may lead to the under- or overprotection of water bodies. This study summarized the sources, distribution, pollution status, and hazards of chloride in China's water bodies. Additionally, we compared and analyzed the basis for setting WQS limits for chloride in China; we systematically analyzed the basis for setting the WQC for chloride in foreign countries, especially the United States. Finally, we collected and screened data on the toxicity of chloride to aquatic organisms; we also used the species sensitivity distribution (SSD) method to derive the WQC value for chloride, which is 187.5 mg·L<sup>-1</sup>. We put forward a recommended value for freshwater WQS for chloride in China: less than 200 mg·L<sup>-1</sup>. The study of a freshwater WQC for chloride is not only a key point of environmental research, but also an urgent demand to ensure water ecological protection in China. The results of this study are of great significance for the environmental management of chloride, protection of aquatic organisms, and risk assessment, especially for the revision of WQSs.
Degradation Mechanism of All-Solid-State Li-Metal Batteries Studied by Electrochemical Impedance Spectroscopy (2022)

Solid-state Li-metal batteries have the potential to achieve both high safety and high energy densities. Among various solid-state fast-ion conductors, the garnet-type Li<sub>7</sub>La<sub>3</sub>Zr<sub>2</sub>O<sub>12</sub> (LLZO) is one of the few that are stable to Li metal. However, the large interfacial resistance between LLZO and cathode materials severely limits the practical application of LLZO. Here a LiCoO<sub>2</sub> (LCO) film was deposited onto an Al-doped LLZO substrate at room temperature by aerosol deposition, and a low interfacial resistance was achieved. The LCO particles were precoated by Li<sub>3</sub>BO<sub>3</sub> (LBO), which melted to join the LCO particles to the LLZO substrate at heating. All-solid-state Li/LLZO/LBO-LCO cells could deliver an initial discharge capacity of 128 mAh g<sup>-1</sup> at 0.2 C and 60 °C and demonstrated relatively high capacity retention of 87% after 30 cycles. The cell degradation mechanism was studied by electrochemical impedance spectroscopy (EIS) and was found to be mainly related to the increase of the interfacial resistance between LBO and LCO. In-situ SEM analysis verified the hypothesis that the increase of the interfacial resistance was caused primarily by interfacial cracking upon cycling. This study demonstrated the capability of EIS as a powerful nondestructive in-situ technique to investigate the failure mechanisms of all-solid-state batteries.
Clinical and Angiographic Predictors of Restenosis After Percutaneous Coronary Intervention (2004)

The preprocedural clinical and angiographic variables from available studies and from the PRESTO trial have only modest predictive ability for restenosis after PCI.
Rewiring the Central Metabolic Pathway for High‐Yield l‐Serine Production in Corynebacterium glutamicum by Using Glucose (2019)

l-Serine is widely used in the pharmaceutical, food, and cosmetic industries. The direct fermentative production of l-serine from glucose in Corynebacterium glutamicum (C. glutamicum) has been achieved but the yield is generally low. In this study, the central metabolic pathway is rewired to direct higher accumulation of glycerate-3-phosphate (3-PG), the precursor for l-serine biosynthesis, thereby freeing up more carbon to enhance l-serine production and yield. To this end, the native phosphotransferase system (PTS) is inactivated by deleting the gene ptsH. Meanwhile, the PTS-independent glucose uptake pathway is activated via overexpression of iolT1, ppgk, and deletion of the transcriptional regulator gene iolR. Furthermore, metabolic changes between PTS and non-PTS strains are elucidated using gas chromatography-tandem mass spectrometry. Based on the metabonomic and enzyme activities analysis, the glycolysis pathway upstream of 3-PG is further enhanced by co-overexpressing pgi, pfkA, and gapA. The resulting strain with all of the modifications mentioned above leads to the l-serine yield of 0.30 g g<sup>-1</sup> glucose (42.8% higher than that of the original strain), which is the highest yield in C. glutamicum by using glucose as the sole carbon source. These strategies can be expanded for the production of other value-added chemicals derived from the intermediates of glycolysis pathway in C. glutamicum.
Recent progress on the vacuum deposition of OLEDs with feature sizes &#x2264; 20um using a contact shadow mask patterned in-situ by laser ablation (2013)

We report progress on the development of a new technique that has the potential to enable the vacuum deposition of OLEDs with feature sizes ≤ 20um, and hence high resolution OLED displays. An OLED device with 16um by 130um sub-pixel size has been successfully demonstrated utilizing the novel idea of the in-situ shadow mask patterning method showing the capability of this method to achieve high resolution OLED patterning. In the approach proposed here, two sheets of polyimide film are mounted on an electrode, and the top sheet of the two stacked sheets is patterned in-situ by laser ablation to create apertures. The protective under sheet is then removed, and OLED materials are deposited through the patterned slits. Since mask alignment is not required in this approach, the technique circumvents the resolution limitations imposed by the difficulty of aligning shadow masks in the conventional techniques, and allows achieving high resolution pixel patterning. Furthermore, shadow effects, another factor that limits resolution in conventional techniques, can be reduced due to the thin plastic shadow mask (~7.5um) that is directly held on the substrate by electrostatic force. In principle, by applying this technique to the standard three color side-by-side sub-pixel matrix scheme, a resolution and aperture ratio of 338ppi and 60%, respectively, can be expected, which is estimated based on the fact that the width of the deposited material is 25um for the 16um wide electrode. In addition, the OLED device fabricated using this technique shows uniform emission and reasonable I-V characteristics similar to those of the OLED fabricated through the standard technique, which indicates that this method does not compromise device quality.