gebhart/patrepeval huggingface dataset:
Efficient Host Material Containing 1,3,5-Triazine Moiety for Red Phosphorescent Organic light-emitting diodes (OLEDs) (2011)

E-mail: sjonglee@lgdisplay.comReceived August 5, 2011, Accepted September 14, 2011Key Words : Triazine, Host, Red phosphorescence, OLEDsOrganic light-emitting diodes (OLEDs) using organicfluorescent dyes as emitting materials have multilayeredstructure of the following order in general: cathode/holeinjection layer/hole transporting layer/emissive layer/elec-tron-transporting layer/electron-injection layer/anode.
Performance analysis of adaptive modulation system combined with transmit/receive diversity (2003)

The average frame error rate (FER) and throughput expressions are derived for adaptive modulation combined with transmit/receive diversity schemes in a Rayleigh fading channel. Based on these derived expressions, the effect of transmit/receive diversity on the link performance of adaptive modulation is investigated. Two transmit diversity schemes are considered for analysis: space-time transmit diversity (STTD) and selection transmit diversity (STD). Our results show that the performance of adaptive modulation can be improved by combining STD, especially when there is a few receive antennas. However, STTD gives little benefit on adaptive modulation.
Intravenous Angiography Using Computerized Fluoroscopy (1980)

During the past several years, we have developed dedicated digital algorithms for real time processing of X-ray transmission imaging data obtained from an image intensifier television fluoroscopy system. Three imaging modes called Mask Mode Fluoroscopy, Mask Mode Radiography, and Time Interval Difference (T. I. D.) Imaging have been tested in over 100 patients since installation of this. apparatus at the University of Wisconsin Clinical Science Center. Feasibility studies have been conducted to determine the capability of these techniques for imaging the entire cardiovascular system, including peripheral arteries, using intravenous injections of iodinated contrast material.
Distributed Operations Planning in the Lumber Supply Chain: Models and Coordination (2009)

Agent-based technology provides a natural approach to model supply chain networks. Each production unit, represented by an agent, is responsible for planning its operations and uses communication to coordinate with the others. In this paper, we study a softwood lumber supply chain made up of three production units (sawing unit, drying unit and finishing unit). We define the local problems and propose agent-specific mathematical models to plan and schedule operations. Then, in order to coordinate these plans between the three agents, we propose different coordination mechanisms. Incorporating these developments, we show how an agent-based simulation tool can be used to integrate planning models and evaluate different coordination mechanisms
Batteries contenant des matériaux d’électrodes analogues au bleu de Prusse (2021)

Ce chapitre donne une introduction pratique à l'utilisation du bleu de Prusse et de ses analogues aux électrodes de batteries Na-ion. Il décrit les propriétés physiques et électrochimiques de ces matériaux, à travers quelques exemples de leur utilisation notamment dans la technologie développée par Natron-Energy.
Nonpolar contributions to conformational specificity in assemblies of designed short helical peptides (2000)

A series of designed short helical peptides was used to study the effect of nonpolar interactions on conformational specificity. The consensus sequence was designed to obtain short helices (17 residues) and to minimize the presence of interhelical polar interactions. Furthermore, the sequence contained a heptad repeat (abcdefg), where positions a and d were occupied by hydrophobic residues Leu, Ile, or Val, and positions e and g were occupied by Ala. The peptides were named according to the identities of the residues in the adeg positions, respectively. The peptides llaa, liaa, ilaa, iiaa, ivaa, viaa, lvaa, vlaa, and vvaa were synthesized, and their characterization revealed marked differences in specificity. An experimental methodology was developed to study the nine peptides and their pairwise mixtures. These peptides and their mixtures formed a vast array of structural states, which may be classified as follows: helical tetramers and pentamers, soluble and insoluble helical aggregates, insoluble unstructured aggregates, and soluble unstructured monomers. The peptide liaa formed stable helical pentamers, and iiaa and vlaa formed stable helical tetramers. Disulfide cross-linking experiments indicated the presence of an antiparallel helix alignment in the helical pentamers and tetramers. Rates of amide proton exchange of the tetrameric form of vlaa were 10-fold slower than the calculated exchange rate for unfolded vlaa. In other work, the control of specificity has been attributed to polar interactions, especially buried polar interactions; this work demonstrated that subtle changes in the configuration of nonpolar interactions resulted in a large variation in the extent of conformational specificity of assemblies of designed short helical peptides. Thus, nonpolar interactions can have a significant effect on the conformational specificity of oligomeric short helices.
Teknisk rapport BASIE : Bärbara sensorer för ökad personsäkerhet (2016)

Industriella arbetsmiljöer utgör trots omfattande säkerhetsarbete fortfarande en risk för hälsa och välbefinnande för arbetstagarna. Moderna sensorer och tekniker möjliggör att upptäcka risker och olyckor i tid och därmed öka säkerheten inom industrier. Industriella miljöer utrustas idag ofta med vältäckande trådlösa kommunikationsnät som möjliggör positionering och kommunikation med sensorer som bärs av personal. Den här rapporten beskriver aktuella tillämpningar och tekniklösningar. Förstudien har inte identifierat någon särskild tillämpning som kraftfullt driver utveckling av bärbara sensorer för industriella miljöer. Däremot har ett flertal lovande tillämpningar hittats som för närvarande provas av industrier eller finns kommersiellt tillgängliga som tidiga produkter. Några initiativ kan stödja flera tillämpningar och/eller funktioner med samma arkitektur och hårdvara. Flera lösningar bygger på positionering och i viss mån kontextanpassning. För fortsatt arbete föreslås utvärdera tillämpningar såsom (1) insamling av information för bättre uppföljning och analys av tillbud och olyckor, (2) stöd för genomförande av säkerhetsförbättrande åtgärder, baserat på analys av tillbud/olycka eller av annan anledning, samt (3) automatisk larmning vid ensamarbete och/eller särskilt riskfyllt arbete. Som ansats för fortsatt arbete föreslås att (A) definiera en flexibel arkitektur som möjliggör tester med olika typer av sensorer för olika tillämpningar, och etablera ett sådant testsystem, (B) identifiera existerande system till vilka integration behövs, samt (C) definiera återanvändbara funktioner för att säkert skydda den personliga integriteten efter behov som styrs av aktuell tillämpning och överenskommelse med företrädare för personal (dvs. fackföreningar), samt (D) hitta tydliga och väl avgränsade tillämpningar som kan provas praktiskt i målmiljöer.
Pharmacokinetics and extrapulmonary beta 2 adrenoceptor activity of nebulised racemic salbutamol and its R and S isomers in healthy volunteers. (1997)

The S-isomer of salbutamol has no detectable activity at extrapulmonary beta 2 adrenoceptors whilst exhibiting higher plasma levels than the R-isomer, in keeping with greater clearance of R-salbutamol than S-salbutamol. Inhalation of R-salbutamol and RS-salbutamol produced dose-related beta 2 responses which were equivalent when compared on a 1:2 microgram basis, despite higher plasma levels of R-salbutamol after administration of the R isomer than after administration of the racemate. Further dose ranging studies are required at steady state to evaluate the pharmacokinetics of R- and S-salbutamol and their relative effects on bronchial hyperreactivity when given on a regular basis to asthmatic subjects.
10 kHz Shifted-Excitation Raman Difference Spectroscopy with Charge-Shifting Charge-Coupled Device Read-Out for Effective Mitigation of Dynamic Interfering Backgrounds (2023)

In this work we demonstrate an advanced concept of a charge-shifting charge-coupled device (CCD) read-out combined with shifted excitation Raman difference spectroscopy (SERDS) capable of operating at up to 10 kHz acquisition rates for the effective mitigation of fast-evolving interfering backgrounds in Raman spectroscopy. This rate is 10-fold faster than that achievable with an instrument we described previously and is overall 1000-fold faster than possible with conventional spectroscopic CCDs capable of operating at up to ∼10 Hz rates. The speed enhancement was realized by incorporating a periodic mask at the internal slit of an imaging spectrometer permitting a smaller shift of the charge on the CCD (8 pixels) to be required during the cyclic shifting process compared with the earlier design which employed an 80-pixel shift. The higher acquisition speed enables the more accurate sampling of the two SERDS spectral channels, enabling it to effectively tackle highly challenging situations with rapidly evolving interfering fluorescence backgrounds. The performance of the instrument is evaluated for heterogeneous fluorescent samples which are moved rapidly in front of the detection system aiming at the differentiation of chemical species and their quantification. The performance of the system is compared with that of the earlier 1 kHz design and a conventional CCD operated at its maximum rate of 5.4 Hz as previously. In all situations tested, the newly developed 10 kHz system outperformed the earlier variants. The 10 kHz instrument can benefit a number of prospective applications including: disease diagnosis where high sensitivity mapping of complex biological matrices in the presence of natural fluorescence bleaching restricts achievable limits of detection; accurate data acquisition from moving heterogeneous samples (or moving a handheld instrument in front of the sample during data acquisition) or data acquisition under varying ambient light conditions (e.g., due to casting shadows, sample or instrument movement). Other beneficial scenarios include monitoring rapidly evolving Raman signals in the presence of largely static background signals such as in situations where a heterogeneous sample is moving rapidly in front of a detection system (e.g., a conveyor belt) in the presence of static ambient light.
Self‐Cleaning, Thermoresponsive P(NIPAAm‐co‐AMPS) Double Network Membranes for Implanted Glucose Biosensors (2016)

A self-cleaning membrane that periodically rids itself of attached cells to maintain glucose diffusion could extend the lifetime of implanted glucose biosensors. Herein, we evaluate the functionality of thermoresponsive double network (DN) hydrogel membranes based on poly(<i>N</i>-isopropylacrylamide) (PNIPAAm) and an electrostatic co-monomer, 2-acrylamido-2-methylpropane sulfonic acid (AMPS). DN hydrogels are comprised of a tightly crosslinked, ionized first network [P(NIPAAm-co-AMPS)] containing variable levels of AMPS (100:0-25:75 wt% ratio of NIPAAm:AMPS) and a loosely crosslinked, interpenetrating second network [PNIPAAm]. To meet the specific requirements of a subcutaneously implanted glucose biosensor, the volume phase transition temperature is tuned and essential properties, such as glucose diffusion kinetics, thermosensitivity, and cytocompatibility are evaluated. In addition, the self-cleaning functionality is demonstrated through thermally driven cell detachment from the membranes in vitro.
Free-Form Design of Electrical Machine Rotor Cores for Production Using Additive Manufacturing (2019)

This work presents a finite element analysis-based, topology optimization (TO) methodology for the combined magnetostatic and structural design of electrical machine cores. Our methodology uses the Bi-directional Evolutionary Structural Optimization (BESO) heuristics to remove inefficient elements from a meshed model based on elemental energies. The algorithm improves the average torque density while maintaining structural integrity. To the best of our knowledge, this work represents the first effort to address the structural-magnetostatic problem of electrical machine design using a free-form approach. Using a surface-mounted permanent magnet motor (PMM) as a case study, the methodology is first tested on linear and nonlinear two-dimensional problems whereby it is shown that the rapid convergence achieved makes the algorithm suitable for real-world applications. The proposed optimization scheme can be easily extended to three dimensions, and we propose that the resulting designs are suitable for manufacturing using selective laser melting, a 3D printing technology capable of producing fully dense high-silicon steel components with good soft magnetic properties. Three-dimensional TO results show that the weight of a PMM rotor can be slashed by 50% without affecting its rated torque profile when the actual magnetic permeability of the 3D-printed material is considered.
Obinutuzumab plus fludarabine and cyclophosphamide in previously untreated, fit patients with chronic lymphocytic leukemia: a subgroup analysis of the GREEN study (2019)

GREEN (NCT01905943) is a nonrandomized, open-label, single-arm, phase 3b study investigating the safety and efficacy of obinutuzumab alone or in combination with chemotherapy in chronic lymphocytic leukemia (CLL). We report the preplanned subgroup analysis of 140 previously untreated, fit CLL patients who received obinutuzumab plus fludarabine and cyclophosphamide (G-FC). The primary endpoint was safety and tolerability. Efficacy was the secondary endpoint. Obinutuzumab 1000 mg was administered intravenously on Day (D)1 (dose split D1‒2), D8 and D15 of Cycle (C)1, and D1 of C2-6 (28-day cycles). Standard intravenous/oral doses of fludarabine and cyclophosphamide were administered on D1-3 of C1-6. Overall, 87.1% of patients experienced grade ≥ 3 adverse events (AEs), including neutropenia (67.1%) and thrombocytopenia (17.1%). Serious AEs were experienced by 42.1% of patients. Rates of grade ≥ 3 infusion-related reactions and infections were 19.3% and 15.7%, respectively. Overall response rate was observed in 90.0%, with 46.4% of patients achieving complete response (CR; including CR with incomplete marrow recovery). Minimal residual disease negativity rates were 64.3% in peripheral blood and 35.7% in bone marrow (intent-to-treat analysis). After a median observation time of 25.6 months, 2 year progression-free survival was 91%. Frontline G-FC represents a promising treatment option for fit patients with CLL.
Cost effectiveness in the organic laboratory (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCost effectiveness in the organic laboratoryD. C. Neckers , Max B. Duncan , James Gainor , and Peter B. Grasse Cite this: J. Chem. Educ. 1977, 54, 11, 690Publication Date (Print):November 1, 1977Publication History Received3 August 2009Published online1 November 1977Published inissue 1 November 1977https://doi.org/10.1021/ed054p690RIGHTS & PERMISSIONSArticle Views98Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (3 MB) Get e-Alerts Get e-Alerts
Conservative Treatment of Pain and Disability due to Spinal Degenerative Changes using Controlled Biofeedback Decompression Mechanical Axial Traction (2015)

Background: Conservative care for degenerative spinal conditions includes several modalities of treatment. Thus, the traction distinguishes as it is capable to elicit the body´s protective proprioceptive response to distraction, reducing intradiscal pressure and minimizing symptoms secondary to disc herniation and axial pain.
Objectives: This work aims to determine the clinical effects of a short treatment course of motorized axial spinal decompression for patients with pain and physical impairment, caused from either lumbar or cervical degenerative disc pathology with no immediate surgical indication.
Methods: A prospective, non-randomized, single center, case series study from patients with both axial and irradiated symptoms from cervical or lumbar spine. Subjects were submitted to a traction protocol using a motorized mechanical axial decompression system (SpineMED®, LAS Brasil, SP). Clinical outcomes as VAS and ODI for lumbar patients 17 and NDI for cervical patients were also collected.
Results: Clinical outcomes improved along the treatment. AP-VAS scores showed an overall reduction of 59% (p<0.001), while IP-VAS scores improved in 56% in the last session (p<0.001). Average ODI showed statistical significance at last session (28 to 18; p=0.014). Average NDI also showed statistical significance at last session (30 to 20; p<0.001). Despite some minor adverse events, no major complication occurred during treatment.
Conclusion: This present spinal decompression treatment significantly improved patient’s clinical outcomes, indicating that this modality of treatment is a safe and effective noninvasive alternative for patients with cervical or lumbar axial pain and radiculopathy.
ChemInform Abstract: Synthesis and Biological Activity of Aldose Reductase Inhibitors with Michael Acceptor Substituents. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Development of a Power Electronics Teaching Lab Incorporating WBG Semiconductors with Plug and Play Modular Hardware and Advanced Curriculum (2019)

This paper presents the development of a power electronics teaching lab to prepare students for the next generation of power electronics engineering using wide bandgap (WBG) semiconductor devices. The objectives are to expedite the transfer of theoretical knowledge to practical experience on WBG semiconductor devices, and at the same time to provide a hands-on understanding of the development of comprehensive power electronics systems. To incorporate different types of semiconductor devices, especially WBG semiconductor switches, and perform various lab experiments from an investigation of component switching characteristics to construction and operation of power converters, a plug-and-play (P&P) modular power electronics education board is developed. The P&P architecture allows easy construction of different power electronics circuits by simply inserting semiconductor daughter boards to the motherboard. To assist students' learning experience, the lab curriculum consisting of lab manuals and supporting resources is developed. Multiple workshops have been held with ECE undergraduate and graduate students to evaluate the performance of the lab. Final assessment and student's feedback are presented as the outcome of the development.
Toward Interface Defaults for Vague Modifiers in Natural Language Interfaces for Visual Analysis (2019)

Natural language interfaces for data visualizations tools are growing in importance, but little research has been done on how a system should respond to questions that contain vague modifiers like "high" and "expensive." This paper makes a first step toward design guidelines for this problem, based on existing research from cognitive linguistics and the results of a new empirical study with 274 crowdsourcing participants. A comparison of four bar chart-based views finds that highlighting the top items according to distribution-sensitive values is preferred in most cases and is a good starting point as a design guideline.
A semicontinuous 3‐column countercurrent solvent gradient purification (MCSGP) process (2007)

The recently developed continuous Multicolumn Countercurrent Solvent Gradient Purification (MCSGP) Process has been reduced to a fully equivalent semicontinuous setup with only three chromatographic columns and three gradient pump modules. Actually the 3-column MCSGP unit can even achieve better performance than the original 6-column process due to an additional degree of freedom, that is a different switching time for the "batch lane" and the "interconnected lane." Experimental results for the 3-column MCSGP unit of the purification of an industrial multicomponent peptide mixture containing 46% of Calcitonin on a reversed phase resin are compared with model simulations. It is concluded, that the model is well suited to predict the system behavior and therefore to design its optimal operating conditions.
Endotoxin and tumor necrosis factor induce interleukin-1 gene expression in adult human vascular endothelial cells. (1986)

Interleukin 1 (IL-1) can induce potentially pathogenic functions of vascular endothelial cells. This mediator was formerly thought to be produced primarily by activated macrophages. We report here that bacterial endotoxin and recombinant human tumor necrosis factor cause accumulation of IL-1 beta mRNA in adult human vascular endothelial cells. IL-1 alpha mRNA was also detected when endothelial cells were exposed to endotoxin under "superinduction" conditions in the presence of cycloheximide. Metabolic labeling of these cells during endotoxin stimulation demonstrated increased synthesis and secretion of immunoprecipitable IL-1 protein that comigrated electrophoretically with the predominant monocyte species. In parallel with increased IL-1 mRNA and protein, endothelial cells exposed to endotoxin also release biologically active IL-1 that was neutralized by anti-IL-1-antibody. Because bloodborne agents must traverse the endothelium before entering tissues, endothelial IL-1 production induced by microbial products or other injurious stimuli could initiate local responses to invasion. Endothelial cells are both a source of and target for IL-1; accordingly, this novel autocrine mechanism might play an early role in the pathogenesis of vasculitis, allograft rejection, and arteriosclerosis.
Retire Superman: Handling Exceptions Seamlessly in a Declarative Visual Programming Language (1996)

Exception handling is widely regarded as a necessity in programming languages today, and almost every programming language in current use supports some form of it. Unfortunately however, most approaches to exception handling involve constructs with unusual powers, and even deviations from the language&amp;apos;s evaluation model. To avoid such devices in our declarative visual programming language, we have devised a fullfeatured approach to exception handling that fits seamlessly into languages that are declarative and visual. Using this approach allows designers of declarative visual programming languages to provide the expressive power previously available only through complex exception handling techniques.