gebhart/patrepeval huggingface dataset:
Compact Stokes shift and fluorescence spectroscopic diagnostics LED ratiometer unit with no moving parts for cancer detection (2012)

A compact Stokes shift and fluorescence spectroscopy (S3) LED device with no moving parts is presented. This device can be used diagnostically for the identification of the native biomolecules within cancerous tissue samples. This S3-LED ratiometer unit measures both the emission and absorption spectra of key native organic biomolecules within a tissue sample by using multiple wavelength LEDs (light emitting diodes) coupled to an optical fiber. Thus, an optical fingerprint of the sample can be obtained. This technique could be used to distinguish benign and malignant tissues, and to check for residual or recurrent carcinoma after treatment, thus reducing the necessity of second biopsies. The S3-LED ratiometer unit was tested in vitro on human breast malignant and normal paired tissue samples.
Additional genetic risk factor for death in children with acute lymphoblastic leukemia: A common polymorphism of the MTHFR gene (2008)

Our data suggest that modification of anti-leukemic treatment should be considered in patients homozygous for c.677C>T polymorphism.
Overview of Mouse Models of Inflammatory Bowel Disease and Their Use in Drug Discovery (2009)

Inflammatory bowel disease (IBD), a condition that affects millions of individuals, encompasses two distinct conditions: Crohn's disease (CD) and ulcerative colitis (UC). CD is an inflammatory condition affecting any part of the digestive tract between the mouth and anus, but, most commonly, the ileum and colon. It is distinguished by the presence of granulomas in the mucosal tissue and patchy areas of transmural inflammation. UC is restricted to the colon and is manifest as continuous inflammation starting from the rectum and extending back towards the cecum. Inflammation in UC is primarily restricted to mucosal layers. Research is ongoing to understand the causality of these two diseases, and advances in understanding of their pathology have resulted from the variety of mouse models of IBD that have emerged since the early 1990s. Described in this unit are contemporary mouse models of these conditions and examples of their use in drug discovery.
Experimental Studies on Fabrication and Thermal Characterization of Shape Memory Polymer Composites with Nanofillers (2022)

Shape memory polymers (SMP) have piqued the interest of the research and development sector due to their new features and immense potential. The polymer matrix epoxy was changed using varied weight percentages of aliphatic monomer‐neopentyl glycol diglycidyl ether (NGDE), and the optimal weight percentage of NGDE was identified. The weight percentages of NGDE‐CNT are 0, 0.3, 0.6, 0.9, 1.2, and 1.5. The use of nanofillers such as carbon nanotubes (CNT) has been promoted to improve the heat conductivity of composites. The thermal conductivity of shape memory polymers has been enhanced through the addition of varying quantities of CNT filler. Mechanical characterizations such as tensile testing, Young’s modulus, impact strength, and heat related tests such as form recovery testing, shape fixity, and recovery time were also investigated. From the investigational outcomes, optimal weight percentage of NGDE loading into epoxy is 15%, and maximum tensile strength attains at 1.2 wt. percent of CNT.
214 The effect of unilateral sciatic neurectomy of fine structure of tibial cortical bone (2005)

The effect of
<title>Dual focus optical head for 0.6-mm and 1.2-mm disks</title> (1994)

We propose a dual focus optical head with a holographic optical element (HOE) which compensates for spherical aberration, allowing it to read both 0.6 mm disks and 1.2 mm disks. The thin disk is read using transmitted light and the thick disk is read using +1st order diffracted light of the blazed HOE. The characteristics of the focused spot, the servo signal detection and the signal of the Compact Disc indicate that both disks can be read by the dual focus optical head.
The introduction of a shared interactive surface into a communal space (2004)

We describe a user study of a large multi-user interactive surface deployed for an initial period within a real world setting. The surface was designed to enable the sharing and exchange of a wide variety of digital media. The setting for the study was the common room of a high school where students come together to mix, socialize, and collaborate throughout the day. We report on how the students use the new technology within their own established communal space. Findings show that the system was used extensively by the students in a variety of ways, including sharing of photos, video clips, and websites, and for facilitating social interaction. We discuss how the interactive shared surface was appropriated by the students and introduced into their everyday lives in ways that both mirrored and extended their existing practices within the communal space.
Noninvasive Detection of New Simian Immunodeficiency Virus Lineages in Captive Sooty Mangabeys: Ability To Amplify Virion RNA from Fecal Samples Correlates with Viral Load in Plasma (2003)

The sooty mangabey (SM) (Cercocebus atys) is the natural host of a simian immunodeficiency virus, termed SIVsm, which gave rise to human immunodeficiency virus type 2. Data on the geographic distribution, prevalence, and genetic diversity of SIVsm in the wild remains limited. To address this issue, noninvasive strategies based on screening SM fecal and urine specimens for SIVsm-specific antibodies and virion RNA (vRNA) were developed, and the results were correlated with viral loads in plasma. Twenty-three SIVsm-infected and 27 uninfected SMs were evaluated. Time-matched urine, fecal and plasma samples were collected over a 2-month period from 16 captive naturally infected SMs. The remaining 7 infected and 27 uninfected SMs were sampled once. Each specimen was subjected to enhanced chemiluminescence-Western blot analysis and nested reverse transcriptase (RT) PCR. The results showed that urine was highly sensitive (96%) and specific (100%) for detection of SIVsm antibodies, while fecal detection was much less sensitive (16%). Conversely, vRNA detection was more sensitive in feces (50%) than in urine (2%) samples. Fecal-vRNA detection correlated with viral loads in plasma (P < 0.002). SMs with detectable fecal vRNA had a mean viral load in plasma of 458,006 copies/ml, while those with undetectable fecal vRNA had a mean viral load in plasma of 29,428 copies/ml. Moreover, for every log increase in the viral load in plasma, the odds of detecting virus in fecal samples increased 87-fold. Genetic diversity of SIVsm in the SM colony was characterized by sequencing partial gag (846 bp) and gp43 (439 bp) fragments. Surprisingly, four new SIVsm lineages were identified, two of which were initially detected by fecal RT-PCR. This study documents the suitability of noninvasive methods for the detection and molecular characterization of new SIV variants. These assays will be useful for studying the phylogeny and epidemiology of SIVsm infections in the wild, and they hold promise as tools for investigating natural SIV infections in endangered nonhuman primates.
DC–DC Converter Implementations Based on Piezoelectric Transformers (2021)

The drive to miniaturize power electronics motivates investigation into alternative passive component technologies such as piezoelectrics, which offer fundamentally higher power density and efficiency capabilities at small scales compared to magnetics. Piezoelectric transformers (PTs) have seen application in dc–dc converters, but these designs typically require additional magnetics for competitive efficiency. In this work, we systematically enumerate isolated and nonisolated dc–dc converter topologies and switching sequences capable of efficiently utilizing PTs as their only energy storage components. The proposed switching sequences maintain high-efficiency behaviors (e.g., zero voltage switching (ZVS), all-positive instantaneous power transfer, and minimal charge circulation) across wide voltage gain and load ranges. We present techniques for deriving these switching sequences’ ZVS regions, estimating PT efficiency, and solving for periodic steady state switching times; these offer insights for comparing and implementing design options. We then verify our analyses in a 180–500 V experimental prototype based on a commercially-available PT, which demonstrates significant efficiency gain through a proposed implementation.
<title>Soft computing and hyperspectral video for background extraction</title> (2000)

This paper presents experimental results of hyperspectral image compression by means of soft computing. Compressions and transmission of hyperspectral data requires intensive computation and sophisticated processing that have been incompatible with on-board real-time operation. Soft computing with intelligent processing optimizes the compression parameters of MPEG 1, tuning them to the specific video content to deliver the highest hyperspectral video compression quality. This soft computing approach is compared with compression based on wavelet transform.
Low frequency noise in 4H-SiC BJTs (2004)

Low frequency noise has been investigated in 4H-SiC BJTs for the first time. In BJTs with the current gain β ≈ 10–15 and unity current gain frequency fT of about 1.5 GHz, the corner frequency fc was found to be fc = 2 × 104 Hz. The value of the coefficient KB, which is the figure of merit for the noise in the region of noise proportional to squared current, was found to be 6 × 10−7 µm2. This value is only an order of magnitude higher than the typical values for high-frequency Si-BJTs.
Adventures in Automating Ecological Image Analysis (TER 3) (2006)

As sensor networks become widely deployed in ecological settings, imaging is increasingly becoming an integral component of the system. Often, ecologists are interested in meta-information about the content of these images, rather than the images themselves. This information is at least tedious, and sometimes completely impractical, to extract manually. We will discuss our experiences with images from two deployments at the James Reserve: the existing minirhizotron systems (with an eye toward the upcoming AMARRS), and the nestbox cameras.
ChemInform Abstract: THERMAL DECOMPOSITION OF BIS(PHOSPHINE)PLATINUM(II) METALLOCYCLES (1977)

Abstract Die thermische Zersetzung der metallcyclischen Verbindungen (IV) wird untersucht und mit der analoger acyclischer Komplexe wie (VII) verglichen.
User-Centric Secure Cell Formation for Visible Light Networks With Statistical Delay Guarantees (2020)

In next-generation wireless networks, providing secure transmission and delay guarantees are two critical goals. However, either of them requires a concession on the transmission rate. In this article, we consider a visible light network consisting of multiple access points and multiple users. Our first objective is to mathematically evaluate the achievable rate under constraints on delay and security. The second objective is to provide a cell formation with customized statistical delay and security guarantees for each user. First, we propose a user-centric design called secure cell formation, in which artificial noise is considered, and flexible user scheduling is determined. Then, based on the effective capacity theory, we derive the statistical-delay-constrained secrecy rate and formulate the cell formation problem as a stochastic optimization problem (OP). Further, based on the Lyapunov optimization theory, we transform the stochastic OP into a series of evolutionary per-slot drift-plus-penalty OPs. Finally, a modified particle swarm optimization algorithm and an interference graph-based user-centric scheduling algorithm are proposed to solve the OPs. We obtain a dynamic independent set of scheduled users as well as secure cell formation parameters. Simulation results show that the proposed algorithm can achieve a better delay-constrained secrecy rate than the existing cell formation approaches.
Fluorescence microscopy tensor imaging representations for large-scale dataset analysis (2020)

Understanding complex biological systems requires the system-wide characterization of cellular and molecular features. Recent advances in optical imaging technologies and chemical tissue clearing have facilitated the acquisition of whole-organ imaging datasets, but automated tools for their quantitative analysis and visualization are still lacking. We have here developed a visualization technique capable of providing whole-organ tensor imaging representations of local regional descriptors based on fluorescence data acquisition. This method enables rapid, multiscale, analysis and virtualization of large-volume, high-resolution complex biological data while generating 3D tractographic representations. Using the murine heart as a model, our method allowed us to analyze and interrogate the cardiac microvasculature and the tissue resident macrophage distribution and better infer and delineate the underlying structural network in unprecedented detail.
Identification of a population of CD4+ CTL that utilizes a perforin- rather than a Fas ligand-dependent cytotoxic mechanism (1996)

Although cytotoxic activity has generally been shown to reside in the CD8+ population of T lymphocytes, there are numerous examples of cytotoxic CD4+ T cells. In the present study, we found that after depletion of CD8+ T cells, CD4+ T cells cultured in short-term in vitro mixed lymphocyte cultures developed strong Ag-specific cytotoxic activity. Such CD4+ CTL lysed both Fas+ and Fas- target cells and developed in Fas ligand-deficient gld mice. Thus, in contrast to several recent reports involving long-term T cell clones or short-term mitogen-activated splenocytes, the cytotoxic activity of these CD4+ CTL is not dependent on Fas-Fas ligand interactions. However, CD4+ cells derived in a similar manner from perforin knockout mice showed greatly decreased target cell lysis, indicating that their cytotoxic activity is primarily dependent on a perforin-based mechanism. The Fas-Fas ligand pathway has been shown to be important in the maintenance of peripheral tolerance, but to have a minimal role in protection against viral and bacterial pathogens. Thus, the existence of a population of CD4+ CTL that utilizes perforin re-emphasizes the likely importance of these cells in a classical defensive role against foreign pathogens, in addition to their already implied role as modulators of the immune response.
MOESM2 of Microbial biosynthesis of lactate esters (2019)

Additional file 2: Figure S1. Expression of the recombinant enzymes in engineered E. coli strains. The positions corresponding to the overexpressed proteins are indicated by arrowheads. Lane M represents protein ladder while lanes T, S, and I are referred to total, soluble, and insoluble proteins, respectively. ①~③, Pyruvate-to-lactate ester module; ④~⑤, Ethanol module; ⑥~⑩, Isobutanol module. Protein sizes were predicted with their amino acids sequences. Figure S2. Effect of lactate esters on cell growth. (A) Specific growth rates of EcDL002 with or without addition of lactate esters. (B) logP values of characterized lactate esters. The values were obtained from http://www.thegoodscentscompany.com . (C–H) Growth curves of EcDL002 with or without addition of (C) n-ethyl lactate (NEL), (D) n-propyl lactate (NPL), (E) n-butyl lactate (NBL), (F) i-butyl lactate (IBL), (G) i-amyl lactate (IAL), and (H) benzyl lactate (BZL). Figure S3. Design of (A) upstream module and (B) downstream module of the ethyl lactate pathway. The RBS Calculator v2.0 software was used to generate synthetic RBS sequences. For the upstream, four synthetic RBS sequences were generated with predicted translation initiation rates at 0.33 and 0.03 between the PAY1 or PAY3 promoter and pdc start codon. For the downstream, six synthetic RBS sequences were generated with predicted translation initiation rates at 90, 9000, and 90000 a.u. between the PT7 promoter and pct or VAAT start codon. Figure S4. (A) Correlation between ester production and the amount of added ethanol in high cell density cultures of EcJW209-212. (B) Correlation between ester production and the RBS strength for VAAT expression in high cell density culture of EcJW213-221.
Roy Laver Swank, MD, PhD (1909–2008) (2009)

Dr. Roy Laver Swank, first Head of Neurology at what is now Oregon Health & Science University, died November 16, 2008, in Portland, at age 99. Dr. Swank was best known for his advocacy of a low-fat diet for multiple sclerosis (MS), but his career encompassed much more. Between 1934 and 2003, he published over 170 scholarly works. His varied research included studies on a stain for myelin undergoing degeneration (the Swank-Davenport stain), thiamine deficiency, chronic combat exhaustion, prevention of microemboli following cardiac bypass surgery, effects of fat on blood viscosity, and diet in the treatment of MS.

Dr. Swank was born in Camas, Washington. He graduated from the University of Washington …
Serial Amnioinfusion as Regenerative Therapy for Pulmonary Hypoplasia in Fetuses With Intrauterine Renal Failure or Severe Renal Anomalies: Systematic Review and Future Perspectives (2020)

The aim of this study was to investigate the effect of serial amnioinfusion therapy (SAT) for pulmonary hypoplasia in lower urinary tract obstruction (LUTO) or congenital renal anomalies (CRAs), introduce patient selection criteria, and present a case of SAT in bilateral renal agenesis. We conducted a search of the MEDLINE, EMBASE, Web of Science, and Scopus databases for articles published from database inception to November 10, 2017. Eight studies with 17 patients (7 LUTO, 8 CRA, and 2 LUTO + CRA) were included in the study. The median age of the mothers was 31 years (N=9; interquartile range [IQR], 29-33.5 years), the number of amnioinfusions was 7 (N=17; IQR, 4.5-21), gestational age at first amnioinfusion was 23 weeks and 4 days (N=17; IQR, 21-24.07), gestational age at delivery was 32 weeks and 2 days (N=17; IQR, 30 weeks to 35 weeks and 6.5 days), birthweight of newborns was 3.7 kg (N= 9; IQR, 2.7-3.7 kg), Apgar score at 1 minute was 2.5 (N=8; IQR, 1-6.5), and Apgar score at 5 minutes was 5.5 (N=8; IQR, 0-7.75). In conclusion, SAT may provide fetal pulmonary palliation by reducing the risk of newborn pulmonary compromise secondary to oligohydramnios. Multidisciplinary research efforts are required to further inform treatment and counseling guidelines. We propose a multidisciplinary approach to prenatal classification of fetuses with LUTO to inform patient selection.
Mapping Structural Damage to Monetary Damage (1993)

Earthquake damage estimation/prediction is still an area which requires expertise and judgment of the experts in the field. Making the predictions/estimates more accurate is an area of active research. The paper presents causal reasoning for damage and an integrated damage model encompassing structural, nonstructural and contents damage. One of the important links in the methodology is mapping structural response damage to monetary damage. In this paper the four cost mapping strategies presented for mapping response damage index to $-damage index are point mapping, interval mapping, probabilistic mapping and fuzzy logic mapping. Experts' opinions are used to generate these functions for reinforced concrete ductile moment resisting frames.
A Photochemical Entry to Depsides:  Synthesis of Gustastatin (2005)

Herein, we propose a modular and general strategy to construct orcinol-type depsides based on the photolysis of functionalized benzodioxinones (I). Notably, resorcinylic esters are obtained without competing isocoumarin (II) formation, exemplified by the first total synthesis of gustastatin in 10 steps from commercially available trihydroxybenzoic acid. [Structure: see text]
Storage and retrieval for image and video databases VII : 26-29 January 1999, San Jose, California (1998)

A collection of 69 papers which were presented at the IST multimedia management and retrieval systems; video retrieval; and image browsing.
Oxidation of primary aromatic amines to nitro derivatives catalysed by iron(III) and manganese(III) tetraaryl porphyrins (1993)

The oxidation of primary aromatic amines to the corresponding nitro derivatives has been observed in catalytic systems (turnovers/hour up to 18000) containing tert-butyl hydroperoxide and metallo-tetraaryl porphyrins (metal = FeIII or MnIII) in the presence of heterocyclic nitrogen bases acting as axial ligands.
Anisotropic Rectangular Metric For Polygonal Surface Remeshing (2013)

We propose a new method for anisotropic polygonal surface remeshing. Our algorithm takes as input a surface triangle mesh. An anisotropic rectangular metric, defined at each triangle facet of the input mesh, is derived from both a user-specified normal-based tolerance error and the requirement to favor rectangleshaped polygons. Our algorithm uses a greedy optimization procedure that adds, deletes and relocates generators so as to match two criteria related to partitioning and conformity.
DEEP COMPLEX-VALUED CONVOLUTIONAL-RECURRENT NETWORKS FOR SINGLE SOURCE DOA ESTIMATION (2022)

International audience
Effects of Hydrazine Concentration on the Properties of ZnS Thin Film Deposited by Chemical Bath Deposition (2011)

The ZnS thin film was deposited by Chemical Bath Deposition(CBD) for the CIGS thin film solar cells as the buffer layer.The Influences of the hydrazine concentration on the growth process and properties of ZnS thin films were investigated.The results show that the hydrazine influences the growth rate distinctly,the increasing of the hydrazine concentration makes the ZnS thin film more compact and thicker.But the hydrazine influences the crystalline of ZnS hardly.All the ZnS thin films are amorphous and of high optical transmittance,and their band gaps are about 3.80 eV,which is suitable for the low wavelength photons to reach the CIGS absorber layer and improve the cell performance.
Nitric Oxide–Dependent Suppression of Thioredoxin-Interacting Protein Expression Enhances Thioredoxin Activity (2006)

NO can regulate cellular redox state by changing expression of Txnip and thioredoxin reductase. This represents a novel antioxidative mechanism of NO independent of posttranslational protein S-nitrosylation of thioredoxin.
Ozone formation from nitrogen oxides (NOx) in clean air. Reply to comments (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOzone formation from nitrogen oxides (NOx) in clean air. Reply to commentsWilliam L. Chameides and Donald H. StedmanCite this: Environ. Sci. Technol. 1976, 10, 9, 937–938Publication Date (Print):September 1, 1976Publication History Published online1 May 2002Published inissue 1 September 1976https://pubs.acs.org/doi/10.1021/es60120a009https://doi.org/10.1021/es60120a009research-articleACS PublicationsRequest reuse permissionsArticle Views30Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Cardiac and Vascular Surgery–Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group (2018)

Contains fulltext : 192663.pdf (Publisher’s version ) (Open Access)