gebhart/patrepeval huggingface dataset:
SUGGESTION OF A TWO-MONTH DELAY BETWEEN EXTREME TEMPERATURES AND RENAL COLIC (2008)

You have accessJournal of Urology1 Apr 2008SUGGESTION OF A TWO-MONTH DELAY BETWEEN EXTREME TEMPERATURES AND RENAL COLIC Nicolas Doumerc, Xavier Game, Marc Mouzin, Federico Sallusto, Michel Soulie, Pascal Rischmann, and Bernard Malavaud Nicolas DoumercNicolas Doumerc More articles by this author , Xavier GameXavier Game More articles by this author , Marc MouzinMarc Mouzin More articles by this author , Federico SallustoFederico Sallusto More articles by this author , Michel SoulieMichel Soulie More articles by this author , Pascal RischmannPascal Rischmann More articles by this author , and Bernard MalavaudBernard Malavaud More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(08)61414-7AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "SUGGESTION OF A TWO-MONTH DELAY BETWEEN EXTREME TEMPERATURES AND RENAL COLIC." The Journal of Urology, 179(4S), p. 481 © 2008 by American Urological AssociationFiguresReferencesRelatedDetails Volume 179Issue 4SApril 2008Page: 481 Advertisement Copyright & Permissions© 2008 by American Urological AssociationMetricsAuthor Information Nicolas Doumerc More articles by this author Xavier Game More articles by this author Marc Mouzin More articles by this author Federico Sallusto More articles by this author Michel Soulie More articles by this author Pascal Rischmann More articles by this author Bernard Malavaud More articles by this author Expand All Advertisement PDF downloadLoading ...
An Integrated Bioprocess for the Expansion and Chondrogenic Priming of Human Periosteum‐Derived Progenitor Cells in Suspension Bioreactors (2017)

The increasing use of microcarrier-based suspension bioreactors for scalable expansion of adult progenitor cells in recent years reveals the necessity of such approaches to address bio manufacturing challenges of advanced therapeutic medicinal products. However, the differentiation of progenitor cells within suspension bioreactors for the production of tissue modules is of equal importance but not well investigated. This study reports on the development of a bioreactor-based integrated process for expansion and chondrogenic priming of human periosteum-derived stem cells (hPDCs) using Cultispher S microcarriers. Spinner flask-based expansion and priming of hPDCs were carried out over 12 days for expansion and 14 days for priming. Characterization of the cells were carried out every 3rd day. Our study showed that hPDCs were able to expand till confluency with fold increase of 3.2±0.64 and to be subsequently primed toward a chondrogenic state within spinner flasks. During expansion, the cells maintained their phenotypic markers, trilineage differentiation capabilities and viability. Upon switching to TGF-β containing media the cells were able to differentiate toward chondrogenic lineage by clustering into mm-sized macrotissues containing hundreds of microcarriers. Chondrogenic priming was further evidenced by the expression of relevant markers at the mRNA level while maintaining their viability. Ectopic implantation of macrotissues highlighted that they were able to sustain their chondrogenic properties for 8 weeks in vivo. The method indicated here, suggests that expansion and relevant priming of progenitor cells can be carried out in an integrated bioprocess using spinner flasks and as such could be potentially extrapolated to other stem and progenitor cell populations.
Biomimetic Culture Reactor for Whole-Lung Engineering (2016)

Decellularized organs are now established as promising scaffolds for whole-organ regeneration. For this work to reach therapeutic practice, techniques and apparatus are necessary for doing human-scale clinically applicable organ cultures. We have designed and constructed a bioreactor system capable of accommodating whole human or porcine lungs, and we describe in this study relevant technical details, means of assembly and operation, and validation. The reactor has an artificial diaphragm that mimics the conditions found in the chest cavity in vivo, driving hydraulically regulated negative pressure ventilation and custom-built pulsatile perfusion apparatus capable of driving pressure-regulated or volume-regulated vascular flow. Both forms of mechanical actuation can be tuned to match specific physiologic profiles. The organ is sealed in an elastic artificial pleura that mounts to a support architecture. This pleura reduces the fluid volume required for organ culture, maintains the organ's position during mechanical conditioning, and creates a sterile barrier allowing disassembly and maintenance outside of a biosafety cabinet. The combination of fluid suspension, negative-pressure ventilation, and physiologic perfusion allows the described system to provide a biomimetic mechanical environment not found in existing technologies and especially suited to whole-organ regeneration. In this study, we explain the design and operation of this apparatus and present data validating intended functions.
ChemInform Abstract: NEUE THIOPHOSPHORIMIDE (1973)

Abstract Die Umsetzung entsprechender stöchiometrischer Mengen von elementarem Schwefel mit Phosphor‐tri‐N‐methylimid (I) ergibt die Thiophosphorimide (IIa) (IIb) bzw. (IIc), die auch durch Umsetzung von Triphenylphosphinsulfid (III) mit (I) erhalten werden können.
ChemInform Abstract: Dutch Resolution, a New Technology in Classical Resolution (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A study of performance of all-digital symbol synchronizers with polynomial interpolators (2002)

Symbol synchronizers including an interpolator have to be considered in an all-digital receiver. Among a variety of interpolators, polynomial interpolators are easiest to implement. In the paper, we examine the performances of two representatives of symbol synchronizers with three types of polynomial interpolating filters and get some interesting results and useful conclusions.
Directional sensitivity of sound-pressure levels in the human ear canal (1989)

Changes in sound pressures measured in the ear canal are reported for broadband sound sources positioned at various locations about the subject. These location-dependent pressures are one source of acoustical cues for sound localization by human listeners. Sound source locations were tested with horizontal and vertical resolution of 10 degrees. Sound levels were measured with miniature microphones placed inside the two ear canals. Although the measured amplitude spectra varied with the position of the microphone in the ear canal, it is shown that the directional sensitivity at any particular frequency of the broadband stimulus is independent of microphone position anywhere within the ear canal. At any given frequency, the distribution of sound pressures as a function of sound source location formed a characteristic spatial pattern comprising one or two discrete areas from which sound sources produced maximum levels in the ear canal. The locations of these discrete areas varied in horizontal and vertical location according to sound frequency. For example, around 8 kHz, two areas of maximum sensitivity typically were found that were located laterally and were separated from each other vertically, whereas, around 12 kHz, two such areas were found located on the horizontal plane and separated horizontally. The spatial patterns of sound levels were remarkably similar among different subjects, although some frequency scaling was required to accommodate for differences in the subjects' physical sizes. Interaural differences in sound-pressure level (ILDs) at frequencies below about 8 kHz tended to increase monotonically with increasing distance of the sound source from the frontal midline and tended to be relatively constant as a function of vertical source location. At higher frequencies, however, ILDs varied both with the horizontal and with the vertical location of the sound source. At some frequencies, asymmetries between the left and right ears in a given subject resulted in substantial ILDs even for midline sound sources. These results indicate the types of horizontal and vertical spatial information that are available from sound level cues over various ranges of frequency and, within a small subject population, indicate the nature of intersubject variability.
ChemInform Abstract: Acetogenic Isoquinoline Alkaloids. Part 11. Regioselective and Atropoisomeric‐Selective Aryl Coupling to Give Naphthyl Isoquinoline Alkaloids: First Total Synthesis of (‐)‐Ancistrocladine. (1987)

Abstract The reductive amination of the ketone (I) with the amine (II) represents the starting step in the synthesis of the separable mixture of the atropoisomeric alcohols (VIIIa) and (IXa).
Being Interactive: Degrees of Separation. (1999)

We offer here evidence for halogen bonding induced by silver nanoparticles (SNPs) in a multilayer containing 4-iodobenzoate ion (4IBI) and CCl(4). SERS experiments show in the monolayer that CCl(4) does not adsorb and 4-iodobenzoic acid (4IBA) adsorbs as 4IBI. SEIRA experiments reveal that 4IBI forms in the multilayer during deposition from CCl(4) on SNPs. Further infrared experiments on clean BaF(2) prove that 4IBI formation caused by underlying SNPs was necessary for CCl(4) inclusion in a 4IBI multilayer. Several potential scenarios involving intermolecular attraction between CCl(4) and 4IBI are proposed to explain the results. Although halogen bonding involving solvents has been theoretically and experimentally demonstrated in solution phase chemistry, in bulk crystals, and at the monolayer level, here it is shown that halogen bonding interactions can also be significant in multilayer films. Results from this work will likely impact a range of applications across diverse fields where halogen bonding in thin films and nucleation chemistry are important.
Structure ofPseudomonas aeruginosaHfq protein (2005)

The structure of the Hfq protein from Pseudomonas aeruginosa was determined using two different ionic conditions. In both cases the molecules formed identical hexameric rings, but some variations in the crystal packing were revealed. Hfq belongs to the family of Sm/LSm proteins, the members of which can form hexameric as well as heptameric rings. Comparative analysis of known structures of this protein family shows that the fragment of the Sm-fold responsible for oligomerization is strongly structurally conserved. In the heptameric ring, three conserved hydrogen bonds between beta-strands of adjacent molecules hold together the monomers, whereas in the hexameric rings of Hfq an additional conserved inaccessible hydrogen bond between neighbouring monomers is observed.
Remote Characterization of Hydrocarbon Filled Reservoirs at the Troll Field by Sea Bed Log (2004)

1 A05 REMOTE CHARACTERIZATION OF HYDROCARBON FILLED RESERVOIRS AT THE TROLL FIELD BY SEA BED LOGGING Introduction SeaBed Logging (SBL) is a remote sensing technique which gives information about subsurface resistivity variations by the use of electromagnetic energy. The method has been demonstrated both theoretically (Kong et al. 2002) and in practice by several calibration and commercial surveys (Ellingsrud et al. 2002 Røsten et al. 2002 Amundsen et al. 2004 and Wicklund and Fanavoll 2004). This abstract presents preliminary results from a scientific SBL survey across the Troll Field. The overall objective of the study is to obtain an improved
3D Tomographic Pattern Synthesis for Enhancing the Quantification of COVID-19 (2020)

The Coronavirus Disease (COVID-19) has affected 1.8 million people and resulted in more than 110,000 deaths as of April 12, 2020. Several studies have shown that tomographic patterns seen on chest Computed Tomography (CT), such as ground-glass opacities, consolidations, and crazy paving pattern, are correlated with the disease severity and progression. CT imaging can thus emerge as an important modality for the management of COVID-19 patients. AI-based solutions can be used to support CT based quantitative reporting and make reading efficient and reproducible if quantitative biomarkers, such as the Percentage of Opacity (PO), can be automatically computed. However, COVID-19 has posed unique challenges to the development of AI, specifically concerning the availability of appropriate image data and annotations at scale. In this paper, we propose to use synthetic datasets to augment an existing COVID-19 database to tackle these challenges. We train a Generative Adversarial Network (GAN) to inpaint COVID-19 related tomographic patterns on chest CTs from patients without infectious diseases. Additionally, we leverage location priors derived from manually labeled COVID-19 chest CTs patients to generate appropriate abnormality distributions. Synthetic data are used to improve both lung segmentation and segmentation of COVID-19 patterns by adding 20% of synthetic data to the real COVID-19 training data. We collected 2143 chest CTs, containing 327 COVID-19 positive cases, acquired from 12 sites across 7 countries. By testing on 100 COVID-19 positive and 100 control cases, we show that synthetic data can help improve both lung segmentation (+6.02% lesion inclusion rate) and abnormality segmentation (+2.78% dice coefficient), leading to an overall more accurate PO computation (+2.82% Pearson coefficient).
Identities of Sequestered Proteins in Aggregates from Cells with Induced Polyglutamine Expression (2001)

Proteins with expanded polyglutamine (polyQ) tracts have been linked to neurodegenerative diseases. One common characteristic of expanded-polyQ expression is the formation of intracellular aggregates (IAs). IAs purified from polyQ-expressing cells were dissociated and studied by protein blot assay and mass spectrometry to determine the identity, condition, and relative level of several proteins sequestered within aggregates. Most of the sequestered proteins comigrated with bands from control extracts, indicating that the sequestered proteins were intact and not irreversibly bound to the polyQ polymer. Among the proteins found sequestered at relatively high levels in purified IAs were ubiquitin, the cell cycle-regulating proteins p53 and mdm-2, HSP70, the global transcriptional regulator Tata-binding protein/TFIID, cytoskeleton proteins actin and 68-kD neurofilament, and proteins of the nuclear pore complex. These data reveal that IAs are highly complex structures with a multiplicity of contributing proteins.
Sensitivity of digital electronic warfare receivers (2002)

The results of a study of the sensitivity of digital electronic warfare (EW) receivers are reported. It is demonstrated with actual digitized data that the sensitivity of a digital receiver can be improved if enough signal processing is applied. The approach presented can be considered as a brute force one. This approach does not provide the best sensitivity that can be accomplished, but it will provide an improvement over conventional EW receivers. In this approach, the digital Fourier transform (DFT) is used to find the frequencies of the input signals. Several DFTs with fixed lengths are used. This approach will approximate the performance of a superheterodyne receiver with a fixed bandwidth, and is equivalent to several channelized receivers, each having a different resolution bandwidth. The technique improves the sensitivity of the receiver with reasonable complexity.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Solvent‐Free Synthesis of Zeolite Crystals Encapsulating Gold–Palladium Nanoparticles for the Selective Oxidation of Bioethanol (2015)

The conversion of bioethanol into valuable products is an important area in the conversion of biomass. We demonstrate the successful synthesis of bimetallic gold-palladium (Au-Pd) nanoparticles encapsulated within S-1 zeolite crystals (AuPd@S-1) by a solvent-free strategy. This strategy allows highly efficient use of the noble metals, with more than 96 % of the gold and palladium being loaded into the final samples. Electron microscopy characterization and investigations with probe molecules confirm that the Au-Pd nanoparticles are encapsulated inside the S-1 crystals. The AuPd@S-1 catalyst is very active for the aerobic oxidation of bioethanol, giving 100 % conversion and 99 % selectivity to acetic acid. Even in the presence of 90 % water, the catalyst still gives a conversion higher than 80 % and a selectivity of 95 %. More importantly, the AuPd@S-1 catalyst exhibits excellent stability in the oxidation of bioethanol. These features are important for future practical applications of the AuPd@S-1 catalyst.
Sinusoid parameter estimation using the fast Fourier transform (2003)

The problem with using the FFT to do spectral estimation is that only a sampled version of the discrete Fourier transform of the input signal is provided. To do parameter estimation on a signal with frequency that does not appear at the output of the FFT, one has to perform spectral interpolation to approximate the original continuous spectrum. The author introduces a new interpolation scheme that allows the frequency and amplitude of a sinusoid to be estimated with high accuracy. The method is based on the fact that spectral convolution introduces spectral leakage that can be observed at the output of an FFT. With the minimum four-sample Blackman-Harris window, this method yields better results than the conventional parabola-fitting technique. The largest error occurs when the frequency is halfway between two frequency bins. Higher-order Taylor series could be used to improve the estimation in the range of 0.45< mod epsilon mod <or=0.5.<<ETX>>
Nondegenerate two-photon absorption from single quantum dot biexcitons (2002)

Summary form only given. Two excitons can bind to form a biexciton through the Coulomb interaction. In a quantum dot (QD), the binding is greatly enhanced due to 3D confinement. Previous work has focused on luminescence from biexciton-to-exciton transitions. We report the first coherent nonlinear optical spectra of a biexcitonic system. Such types of studies provide vital information on the exciton/biexciton lifetime as well as the optically-induced quantum coherence and its decay. The realization of coherent optical devices based on QD systems, such as proposed for quantum logic operations, relies critically on these measurements.
A new strategy to ERADicate HER2-positive breast tumors? (2015)

HER2-positive breast cancers that have become resistant to HER2-targeting agents, such as trastuzumab (also known as Herceptin), have limited treatment options. In this issue of Science Signaling, Singh et al. have identified a characteristic increase in the endoplasmic reticulum (ER)-associated degradation (ERAD) system in HER2-positive tumors as a mechanism of relieving proteotoxic stress. Synthetic lethality arising from targeted disruption of ERAD signaling in conjunction with other HER2-dependent signaling may improve therapeutic management of this difficult class of breast tumors.
A Role for IFITM Proteins in Restriction of Mycobacterium tuberculosis Infection (2015)

The interferon (IFN)-induced transmembrane (IFITM) proteins are critical mediators of the host antiviral response. Here, we expand the role of IFITM proteins to host defense against intracellular bacterial infection by demonstrating that they restrict Mycobacterium tuberculosis (MTb) intracellular growth. Simultaneous knockdown of IFITM1, IFITM2, and IFITM3 by RNAi significantly enhances MTb growth in human monocytic and alveolar/epithelial cells, whereas individual overexpression of each IFITM impairs MTb growth in these cell types. Furthermore, MTb infection, Toll-like receptor 2 and 4 ligands, and several proinflammatory cytokines induce IFITM1-3 gene expression in human myeloid cells. We find that IFITM3 co-localizes with early and, in particular, late MTb phagosomes, and overexpression of IFITM3 enhances endosomal acidification in MTb-infected monocytic cells. These findings provide evidence that the antiviral IFITMs participate in the restriction of mycobacterial growth, and they implicate IFITM-mediated endosomal maturation in its antimycobacterial activity.
Supramolecular Assembles of Carbon Nanohorns and Porphyrin for Photovoltaic Devices (2010)

Abstract not Available.
Tissue memory CD4+ T cells expressing IL-7 receptor-alpha (CD127) preferentially support latent HIV-1 infection (2020)

The primary reservoir for HIV is within memory CD4+ T cells residing within tissues, yet the features that make some of these cells more susceptible than others to infection by HIV is not well understood. Recent studies demonstrated that CCR5-tropic HIV-1 efficiently enters tissue-derived memory CD4+ T cells expressing CD127, the alpha chain of the IL7 receptor, but rarely completes the replication cycle. We now demonstrate that the inability of HIV to replicate in these CD127-expressing cells is not due to post-entry restriction by SAMHD1. Rather, relative to other memory T cell subsets, these cells are highly prone to undergoing latent infection with HIV, as revealed by the high levels of integrated HIV DNA in these cells. Host gene expression profiling revealed that CD127-expressing memory CD4+ T cells are phenotypically distinct from other tissue memory CD4+ T cells, and are defined by a quiescent state with diminished NFκB, NFAT, and Ox40 signaling. However, latently-infected CD127+ cells harbored unspliced HIV transcripts and stimulation of these cells with anti-CD3/CD28 reversed latency. These findings identify a novel subset of memory CD4+ T cells found in tissue and not in blood that are preferentially targeted for latent infection by HIV, and may serve as an important reservoir to target for HIV eradication efforts.
A dual fed and a dual frequency slots-loaded triangular microstrip antenna (2002)

As the advances in wireless communication technology are very rapid, there have been vast research in dual fed microstrip antennas in order to isolate the Tx and the Rx signals and for a variable profile dual frequency patch. For example, the study of dual frequency operation has been carried out with the via-hole feed and microstrip line feed. Using a dual resonant microstrip antenna would be better than the broadband microstrip antenna, because it is very difficult that a single layer microstrip antenna has a bandwidth which covers the up- and down-link of the IMT-2000 system. In this article, a dual resonant triangular microstrip antenna with slots-loaded and the characteristics of the isolation between the Tx and the Rx ports using inset microstrip line feed and probe feed methods are proposed and experimentally studied for the case of a thin substrate.
Palladium nanoparticles incorporated within sulfonic acid-functionalized MIL-101(Cr) for efficient catalytic conversion of vanillin (2015)

The developed Pd/SO<sub>3</sub>H-MIL-101(Cr) catalyst exhibits novel synergy in hydrodeoxygenation of vanillin at low H<sub>2</sub> pressure under mild conditions.
Supplementary Figure 7 from Vulnerabilities of <i>PTEN</i>–<i>TP53</i>-Deficient Prostate Cancers to Compound PARP–PI3K Inhibition (2023)

&lt;p&gt;PDF - 138K, Survival curves of the in vivo treatment of Olaparib and BKM120.&lt;/p&gt;
Analyse de la consommation énergétique de l'électro-déshydratation des boues résiduaires urbaines (2013)

International audience
Millimeter-Wave Imaging Technologies and Their Applications (2007)

A compact wideband millimeter wave detection element for the 35 GHz band has been developed mainly for passive imaging technologies. Applications of this element include security areas as well as food industry areas. Human bodies can be detected through fire flame, the thermal radiation emitted from fruit changes as it is ripening. Timber with knots and/or damages by white ants, and food temperature in cardboard box can be detected through passive mm-wave imaging.