gebhart/patrepeval huggingface dataset:
Front Matter: Volume 9312 (2015)

This PDF file contains the front matter associated with SPIE Proceedings Volume 9312, including the Title Page, Copyright information, Table of Contents, Invited Panel Discussion, and Conference Committee listing.
Subwavelength silicon microcavities (2009)

We present a study of the first silicon microdisk resonators which are smaller than the free-space resonant wavelength in all spatial dimensions. Spectral details of whispering gallery modes with azimuthal mode number m = 4-7 are measured in microdisks with diameters between 1.35 and 1.89microm and are studied at wavelengths from 1.52 to 1.62microm. For the structures considered here, m = 5 is the highest azimuthal mode order in a subwavelength cavity and has measured Q = 1250. These results agree well with theoretical calculations using a finite difference frequency domain method and fit an exponential scaling law relating Q to disk radius via m.
Oxygen Sensors for Lean Combustion Engines (2001)

This chapter contains sections titled: Introduction Planar Potentiometric Oxygen Sensors Planar Limiting Current Oxygen Sensors Conclusions Acknowledgments
Machine learning–derived major adverse event prediction of patients undergoing transvenous lead extraction: Using the ESC EHRA EORP European lead extraction ConTRolled ELECTRa registry (2022)

ML models incrementally improved risk prediction for identifying those at risk of MAEs. The SNN has the additional advantage of providing a personalized finite risk assessment for patients. This may aid patient decision making and allow better preoperative risk assessment and resource allocation.
A Comparison of Rowing Technique at Different Stroke Rates: A Description of Sequencing, Force Production and Kinematics (2004)

Low back pain is the commonest musculoskeletal complaint in rowers. Research into the relationship between rowing technique, the forces generated during the rowing stroke and the kinematics of spinal motion are increasing, but to date none have investigated the impact of different rowing intensities on this relationship. A technique has been developed using an electromagnetic motion system and strain gauge instrumented load cell to measure spinal and pelvic motion and force generated at the handle during rowing on an exercise rowing ergometer. Using this technique ten collegiate male rowers (mean age 22.1+/-2.8 years) from local rowing clubs were investigated. The test protocol consisted of rowing on an ergometer at three different stroke ratings; 17-20 strokes per minute; 24-28 strokes per minute; and 28-36 strokes per minute. Each rating was held for four minutes, with a five-minute rest between each rating. Marked changes in the force output curve and lumbopelvic kinematics were observed at the different rowing intensities. Although there was no change in the magnitude of peak torque generated during the different rating, there was a marked shift in when this occurred during the stroke. In terms of kinematic changes, these centred around changes in pelvic rotation at the catch and finish stages of the stroke with significantly less anterior rotation occurring at the catch position at higher rowing intensities. To conclude, this study suggests that rowing kinematics and force profiles do change at higher rowing intensities. These changes may be an important factor with respect to injury mechanisms, however, further work is required at an elite level.
Signal enhancement ratio imaging of the lung parenchyma with ultra‐fast steady‐state free precession MRI at 1.5T (2018)

2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2018.
Augmented Reality Application for Aiding Tumor Resection in Skull-Base Surgery (2019)

Treatment of cancer patients has improved with advances in tumor resection techniques for skull-base surgery. However, a secondary procedure or chemotherapy is often required to treat residual tumor to prevent recurrence. With the advent of assistive technology, such as augmented reality, a myriad of possibilities have been facilitated for the field of surgery. This work explores the development of an augmented reality application to improving the tumor margin excised during surgical procedures, with a focus on skull-base surgery. An isosurface reconstruction algorithm was integrated with the Microsoft HoloLens, a self-contained holographic computer, to enable visualization of Computed Tomography (CT) imaging superimposed in 3D on the patient. The results suggest that though the device has limitations at its current stage, the Microsoft HoloLens could be used for planning and overlaying the imaging information on the patient for removal of lesions in real-time. The modules developed could also be extended to other types of surgery involving visualization of Digital Imaging and Communication in Medicine (DICOM) files.
Evaluation of the impact of surgical aortic valve replacement on short-term cardiovascular and cerebrovascular controls through spontaneous variability analysis (2020)

We assessed the effect of surgical aortic valve replacement (SAVR) on cardiovascular and cerebrovascular controls via spontaneous variability analyses of heart period, approximated as the temporal distance between two consecutive R-wave peaks on the electrocardiogram (RR), systolic, diastolic and mean arterial pressure (SAP, DAP and MAP) and mean cerebral blood flow (MCBF). Powers in specific frequency bands, complexity, presence of nonlinear dynamics and markers of cardiac baroreflex and cerebral autoregulation were calculated. Variability series were acquired before (PRE) and after (POST) SAVR in 11 patients (age: 76±5 yrs, 7 males) at supine resting and during active standing. Parametric spectral analysis was performed based on the autoregressive model. Complexity was assessed via a local nonlinear prediction approach exploiting the k-nearest-neighbor strategy. The presence of nonlinear dynamics was checked by comparing the complexity marker computed over the original series with the distribution of the same index assessed over a set of surrogates preserving distribution and power spectral density of the original series. Cardiac baroreflex and cerebral autoregulation were estimated by assessing the transfer function from SAP to RR and from MAP to MCBF and squared coherence function via the bivariate autoregressive approach. We found that: i) orthostatic challenge had no effect on cardiovascular and cerebrovascular control markers in PRE; ii) RR variance was significantly reduced in POST; iii) complexity of SAP, DAP and MAP variabilities increased in POST with a greater likelihood of observing nonlinear dynamics over SAP compared to PRE at supine resting; iv) the amplitude of MCBF variations and MCBF complexity in POST remained similar to PRE; v) cardiac baroreflex sensitivity decreased in POST, while cerebrovascular autoregulation was preserved. SAVR induces important changes of cardiac and vascular autonomic controls and baroreflex regulation in patients exhibiting poor reactivity of cardiovascular regulatory mechanisms, while cerebrovascular autoregulation seems to be less affected.
Extracorporeal Enzymatic Removal of Low Density Lipoproteins in Rabbits: Efficacy and Safety (1993)

An extracorporeal circuit incorporating a plasma separator reactor (PSR) was designed to modify low density lipoproteins (LDL). The PSR was tested in vivo with hypercholesterolemic New Zealand White rabbits. The bioreactor enzymatically converts LDL to a form that can be removed by the body at an enhanced rate. The physiological response of hypercholesterolemic New Zealand White rabbits to 90 minute extracorporeal treatments was monitored. The total plasma cholesterol concentration in the treated rabbits fell sharply (up to 40% decrease) during and following the treatment. Results of safety tests indicate no significant enzyme leaching from the device, no disruption or damage to erythrocytes, no increase in white blood cell count and no liver damage as indicated by five enzyme assays. All safety measurements suggest that the treatment is safe.
Figure S2 from TAS0728, A Covalent-binding, HER2-selective Kinase Inhibitor Shows Potent Antitumor Activity in Preclinical Models (2023)

&lt;p&gt;Body weight changes in mice&lt;/p&gt;
Interactions of intestinal lymph flow and secretion. (1977)

The relationship between lymph flow and intestinal secretion was studied in an isolated, vascularly perfused cat ileal preparation in which secretion was caused by three different means: 1) plasma dilution from a constant infusion of Tyrode solution (2.5 ml/min per kg), 2) elevation of intestinal venous pressure to 30 mmHg, and 3) exposure to cholera toxin. In the plasma-dilution group, lymph flow attained a peak value of 38 times control at 60-90 min following the onset of the infusion, after which time lymph flow progressively decreased. Concomitant to the rapid decrease in lymph flow was a rapid increase in intestinal secretion (filtration secretion). A similar pattern, i.e., a rapid increase in lymph flow followed by a progressive decrease in lymph flow and concomitant increase in filtration secretion, was observed in the venous hypertension group; however, peak lymph flow (20 X control) was observed within 10 min of the pertubation. No correlation between the onset of intestinal secretion and a decline in lymph flow was observed in the cholera toxin group.
First Human Brain Images of the jPET-D4 Using 3D OS-EM with a Pre-computed System Matrix (2006)

The JPET-D4 is a novel brain PET scanner which aims to achieve not only high spatial resolution but also high scanner sensitivity by measuring 4-layer depth-of-interaction (DOI) information. In this work, we present software strategies for 3D image reconstruction and imaging performance of the JPET-D4 prototype. The dimensions of a system matrix for the JPET-D4 become 4 billion (coincidence pairs) times 5 million (image elements) when a 25 cm diameter FOV is sampled by a 1.5 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> voxel. The size of the system matrix is estimated at 142 peta (P) byte with the accuracy of 8 byte per element. The on-the-fly calculation is usually used to deal with a huge system matrix. However we can not avoid the extension of calculation time when we improve the accuracy of system modeling. In this work, we proposed an alternative approach based on the pre-calculation of the system matrix. The 142 P byte system matrix was compressed into 13.4GB by (1) reducing zero elements, (2) applying the 3D-expanded DOI compression method, (3) factorizing with respect to ring differences and (4) restricting the maximum ring difference to 54 (with only 10% loss of the number of LORs). Histogram-based 3D OSEM based on geometrical system modeling was implemented. After evaluating basic imaging performance though phantom experiments, a normal volunteer was scanned and the first human brain images were obtained.
ChemInform Abstract: Increasing the Structural Span of Alkyne Metathesis. (2014)

Abstract Several new catalysts for alkyne metathesis, e.g. MMC, are introduced.
Simultaneous Measurements of Auto-Immune and Infectious Disease Specific Antibodies Using a High Throughput Multiplexing Tool (2012)

Considering importance of ganglioside antibodies as biomarkers in various immune-mediated neuropathies and neurological disorders, we developed a high throughput multiplexing tool for the assessment of gangliosides-specific antibodies based on Biolpex/Luminex platform. In this report, we demonstrate that the ganglioside high throughput multiplexing tool is robust, highly specific and demonstrating ∼100-fold higher concentration sensitivity for IgG detection than ELISA. In addition to the ganglioside-coated array, the high throughput multiplexing tool contains beads coated with influenza hemagglutinins derived from H1N1 A/Brisbane/59/07 and H1N1 A/California/07/09 strains. Influenza beads provided an added advantage of simultaneous detection of ganglioside- and influenza-specific antibodies, a capacity important for the assay of both infectious antigen-specific and autoimmune antibodies following vaccination or disease. Taken together, these results support the potential adoption of the ganglioside high throughput multiplexing tool for measuring ganglioside antibodies in various neuropathic and neurological disorders.
Contact angle of air bubbles attached to an air-water surface in foam applications (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTContact angle of air bubbles attached to an air-water surface in foam applicationsL. A. Lobo, A. Nikolov, A. Dimitrov, P. Kralchevski, and D. T. WasanCite this: Langmuir 1990, 6, 5, 995–1001Publication Date (Print):May 1, 1990Publication History Published online1 May 2002Published inissue 1 May 1990https://pubs.acs.org/doi/10.1021/la00095a019https://doi.org/10.1021/la00095a019research-articleACS PublicationsRequest reuse permissionsArticle Views632Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Supplementary Figure 1 from STAT3 Mediates Resistance to MEK Inhibitor through MicroRNA miR-17 (2023)

Supplementary Figure 1 from STAT3 Mediates Resistance to MEK Inhibitor through MicroRNA miR-17
Biological Strategies for Improved Osseointegration and Osteoinduction of Porous Metal Orthopedic Implants (2014)

The biological interface between an orthopedic implant and the surrounding host tissue may have a dramatic effect upon clinical outcome. Desired effects include bony ingrowth (osseointegration), stimulation of osteogenesis (osteoinduction), increased vascularization, and improved mechanical stability. Implant loosening, fibrous encapsulation, corrosion, infection, and inflammation, as well as physical mismatch may have deleterious clinical effects. This is particularly true of implants used in the reconstruction of load-bearing synovial joints such as the knee, hip, and the shoulder. The surfaces of orthopedic implants have evolved from solid-smooth to roughened-coarse and most recently, to porous in an effort to create a three-dimensional architecture for bone apposition and osseointegration. Total joint surgeries are increasingly performed in younger individuals with a longer life expectancy, and therefore, the postimplantation lifespan of devices must increase commensurately. This review discusses advancements in biomaterials science and cell-based therapies that may further improve orthopedic success rates. We focus on material and biological properties of orthopedic implants fabricated from porous metal and highlight some relevant developments in stem-cell research. We posit that the ideal primary and revision orthopedic load-bearing metal implants are highly porous and may be chemically modified to induce stem cell growth and osteogenic differentiation, while minimizing inflammation and infection. We conclude that integration of new biological, chemical, and mechanical methods is likely to yield more effective strategies to control and modify the implant-bone interface and thereby improve long-term clinical outcomes.
The Aspartic Proteinase of Barley Is a Vacuolar Enzyme That Processes Probarley Lectin in Vitro (1994)

Previous work suggested that the aspartic proteinase from Hordeum vulgare (HvAP) would be a vacuolar protein in plant cells. Based on N-terminal sequencing we show that the in vitro-translated protein was translocated into the lumen of microsomal membranes, causing a concomitant removal of 25 amino acid residues from the protein. Vacuoles were purified from barley leaf protoplasts and were shown to contain all of the aspartic proteinase activity found in the protoplasts. This vacuolar localization of HvAP was confirmed with immunocytochemical electron microscopy using antibodies to HvAP in both barley leaf and root cells. In an attempt to discern a function for this protease, we investigated the ability of HvAP to process the C-terminal proregion of barley lectin (BL) in vitro. Prolectin (proBL), expressed in bacteria, was processed rapidly when HvAP was added. Using several means, we were able to determine that 13 amino acid residues at the C terminus of proBL were cleaved off, whereas the N terminus stayed intact during this incubation. Immunohistochemical electron microscopy showed that HvAP and BL are co-localized in the root cells of developing embryos and germinating seedlings. Thus, we propose that the vacuolar HvAP participates in processing the C terminus of BL.
Theory and simulations of homonuclear spin pair systems in rotating solids (1990)

The theory of nuclear magnetic resonance (NMR) on a solid sample containing pairs of coupled homonuclear spins-1/2, rotating in a large magnetic field, is presented. The time dependence introduced by the sample rotation, in conjunction with the spin–spin coupling, makes it appear that each of the central two levels in the four-level system split into a pair of ‘‘virtual states.’’ Each of the eight possible single-quantum coherences between the virtual states and the two outer levels in general contribute to the spectrum, although four of these contributions are forbidden unless a rotational resonance occurs (matching of an integer multiple of the spinning speed with the difference in isotropic shifts). Analytical line shapes for the case of vanishing shift anisotropy are given and techniques for numerical simulation in the general case demonstrated. The theory of Zeeman magnetization exchange in the presence of zero-quantum dephasing is presented.
Assessment of myocardial function and perfusion in a canine model of non‐occlusive coronary artery stenosis using fast magnetic resonance imaging (1999)

Magnetic resonance (MR) functional and perfusion imaging were employed in a canine model of coronary artery stenosis (n = 6) for the quantification of functional and perfusion deficits before and after dipyridamole administration. Left anterior descending and circumflex (LCX) coronary blood flow were measured continuously after placing Doppler flowmeters. Inversion recovery gradient echo images during the transit of MR contrast medium gadolinium-benzyloxypropionictetraacetate dimeglumine (Gd-BOPTA/Dimeg) and fast breath-hold cine MR images were acquired at baseline, during LCX stenosis in basal state, and during LCX stenosis with vasodilation (dipyridamole 0.5 mg/kg). The extent of the functional defect and perfusion defect was expressed as percent of left ventricle (LV) circumference. During stenosis (LCX flow: 62.6 ± 5.6% of baseline) the extent of the functional defect was slightly larger than the perfusion defect (11.0 ± 1.8% versus 6.3 ± 1.7% of LV circumference, respectively; P < 0.01). During vasodilation the extent of the functional defect was considerably smaller than the perfusion defect (25.3 ± 2.5% versus 35.3 ± 3.5%; P < 0.01). Thus, the sizes of ischemic regions displayed by MR perfusion defect and functional defect differ from each other. J. Magn. Reson. Imaging 1999; 9:101–110. J. Magn. Reson. Imaging 1999;9:101–110 © 1999 Wiley-Liss, Inc.
A Triple-Blind, Placebo-Controlled Randomized Trial of the Effect of Bilateral Alternating Somatosensory Stimulation on Reducing Stress-Related Cortisol and Anxiety During and After the Trier Social Stress Test (2019)

The aim of this clinical study was to determine the efficacy of bilateral alternating somatosensory stimulation for the management of stress and anxiety during and after the Trier Social Stress Test (TSST), a laboratory procedure for reliably inducing stress in human subjects. For this, a randomized, placebo-controlled, triple-blinded clinical trial of 80 qualified subjects was conducted. Subjects were randomized into two groups, a treatment group (n=40) and a control (placebo) group (n=40). Metrics of emotional stress assessed were a subjective rating of the level of emotional stress and salivary cortisol levels, both obtained at 3 timepoints: before treatment (baseline), immediately following completion of the TSST, and after 20 minutes of rest following completion of the TSST. Results showed that the treatment group had a statistically greater decrease in the subjective rating of stress relative to the control group both immediately following the TSST and 20 minutes after the TSST. Salivary cortisol levels in the treatment group were also lower than the control group at those same time points. These results suggest that bilateral alternating somatosensory stimulation may be effective in reducing subjective levels of stress and anxiety. It also may actively attenuate stress-related cortisol levels, which may reflect a mechanism for reducing cortisol-induced inflammation back to baseline after exposure to stressful situations.
Polymyxin B‐immobilized fiber column direct hemoperfusion and continuous hemodiafiltration in premature neonates with systemic inflammatory response syndrome (2016)

Active treatment with PMX-DHP and CHDF was helpful in the reduction of days on inhaled oxygen and tracheal intubation in preterm SIRS infants with hypercytokinemia. Further prospective randomized studies are warranted.
On the effect of localization errors on geographic face routing in sensor networks (2004)

In the absence of location errors, geographic routing - using a combination of greedy forwarding and face routing - has been shown to work correctly and efficiently. The effects of location errors on geographic routing have not been studied before. In this work we provide a detailed analysis of the effects of location errors on the correctness and performance of geographic routing in static sensor networks. First, we perform a micro-level behavioral analysis to identify the possible protocol error scenarios and their conditions and bounds. Then, we present results from an extensive simulation study of GPSR and GHT to quantify the performance degradation due to location errors. Our results show that even small location errors (of 10% of the radio range or less) can in fact lead to incorrect (non-recoverable) geographic routing with noticeable performance degradation. We then introduce a simple modification for face routing that eliminates probable errors and leads to near perfect performance.
Mountain Tops and Wilderness: A New Vision (2007)

In this tutorial, we will focus on emerging deployable displays and displays worn on the body to support mobile users. Designs suitable for integration into the eyeglasses form factor will also be discussed. Article not available.