gebhart/patrepeval huggingface dataset:
Construction of Thai Lexicon from Existing Dictionaries and Texts on the Web (2006)

A lexicon is an important linguistic resource needed for both shallow and deep language processing. Currently, there are few machine-readable Thai dictionaries available, and most of them do not satisfy the computational requirements. This paper presents the design of a Thai lexicon named the TCL's Computational Lexicon (TCLLEX) and proposes a method to construct a large-scale Thai lexicon by re-using two existing dictionaries and a large number of texts on the Internet. In addition to morphological, syntactic, semantic case role and logical information in the existing dictionaries, a sort of semantic constraint called selectional preference is automatically acquired by analyzing Thai texts on the web and then added into the lexicon. In the acquisition process of the selectional preferences, the so-called Bayesian Information Criterion (BIC) is applied as the measure in a tree cut model. The experiments are done to verify the feasibility and effectiveness of obtained selection preferences.
Using multiple contoursets to represent structures in 3D images (2007)

This paper presents a unique framework for representing volumes of interest (VOI) within 3D images. The framework contains a four-tier VOI tree structure, and three Boolean operations defined on top of the structures. The new framework allows complex geometries to be represented, while permitting unambiguous interpolation to be performed between image slices without the necessity for manual component labeling. This framework has been used in the context of treatment planning for the CyberKnife® radiosurgery system, allowing anatomical structures and dose constraints to be easily and intuitively created.
Supplementary Table 8 from Mapping the HLA Ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation (2023)

&lt;p&gt;Statistics over-represented peptides HLA class II&lt;/p&gt;
Development of a superhydrophobic cellulose fabric via enzyme treatment and surface hydrophobization (2020)

Enzymatic hydrolysis is a common finishing method for cellulosic materials, to improve fabric softness, appearance, and surface properties. However, its potential to trigger superhydrophobicity has not been studied in depth. In this study, a superhydrophobic cellulose fabric was fabricated in two steps. Micro-/nano-hierarchical roughness on the fabric surface was achieved by cellulase from Aspergillus niger, through enzymatic hydrolysis. Subsequently, hydrophobization was carried out by a dip coating method, using polydimethylsiloxane (PDMS). Enzyme concentration and treatment temperature were varied to find the values that provided the greatest superhydrophobicity. As enzyme concentration and temperature increased, the nano-scale roughness increased, along with weight reduction. The degree of crystallinity and reduction in tensile strength were also increased with weight loss via enzyme hydrolysis. As air pockets were formed by micro-/nano-structures on the fiber surface, the water contact angle increased and the shedding angle tended to decrease. The sample treated with 5 g/l enzyme at 60 ℃ for 60 min and coated with PDMS 1 wt.% coating solution had the greatest superhydrophobicity, with a water contact angle of 162° and a shedding angle of 7.0°. The weight loss and reduction in tensile strength of the developed superhydrophobic fabrics were 2.9% and 39.0%, respectively. This approach reduces the necessity for an additional process to introduce nano-scale roughness, and it has the potential to produce superhydrophobic cellulosic biomass for outdoor clothing.
Toward network controlled IP traffic offloading (2013)

Operator controlled IP traffic offloading in cellular networks has been a lively topic in both product and standard development during recent years. Specifically, 3GPP has developed multiple IP traffic offloading solutions for their system architecture, typically requiring 3GPP-specific modifications for user equipment. We argue that an adequate lightweight access technology agnostic IP traffic offloading system is achievable with a generic internet layer solution. Such a solution can still utilize 3GPP system properties for operators to push offloading policies securely into mobile devices. We discuss existing 3GPP-specified offloading solutions and present three variations of our internet layer traffic offloading implementations, and compare them against 3GPP-specified solutions. Our hands-on experience in operator networks shows that such a direction is feasible and promising.
Generation Pattern of Sulfur Containing Gases from Anaerobically Digested Sludge Cakes (2006)

Eleven dewatered sludge cakes collected from anaerobic digesters at different treatment plants were evaluated for the amount, type, and pattern of odorous gas production. All but one of the sludge cakes were from mesophilic anaerobic digesters. One was from a thermophilic digester. The pattern and quantities of sulfur gases were found to be unique for each of the samples with regard to the products produced, magnitude, and subsequent decline. The main odor-causing chemicals were volatile sulfur compounds, which included hydrogen sulfide, methanethiol, and dimethyl sulfide. Volatile sulfur compound production peaked in 3 to 8 days and then declined. The decline was a result of conversion of organic sulfur compounds to sulfide. In one side-by-side test, a high-solids centrifuge cake generated more odorous compounds than the low-solids centrifuge cake. The data show that anaerobic digestion does not eliminate the odor potential of anaerobically digested dewatered cakes.
HrpG, a KeyhrpRegulatory Protein ofXanthomonas campestrispv.vesicatoriaIs Homologous to Two-Component Response Regulators (1996)

Xanthomonas campestris pv. vesicatoria is the causal agent of bacterial spot disease of pepper and tomato plants. Expression of its basic pathogenicity genes, the hrp genes, is induced in planta and in XVM2 medium and is dependent on the hrp regulatory gene hrpXv for five out of six loci in the 23-kb hrp cluster. Here we describe the isolation of a novel hrp gene, hrpG, that was identified after chemical mutagenesis and that is located next to the hrpXv gene. In a hrpG mutant induction of expression of the seven loci hrpA to hrpF, and hrpXv is abolished, suggesting that hrpG functions at the top of the hrp gene regulatory cascade. hrpG is the only gene in the locus and encodes a putative protein of 263 amino acids with a molecular mass of 28.9 kDa. The HrpG amino acid sequence shows similarity to response regulator proteins of the OmpR subclass of two-component systems, being mostly related to the ChvI proteins of Agrobacterium tumefaciens and Rhizobium spp., and TctD of Salmonella typhimurium. Expression of hrpG is low in complex medium, is increased in XVM2 by a factor of four, and is independent of other hrp loci. A model on hrp gene regulation in Xanthomonas campestris pv. vesicatoria is discussed.
Performance of delay-dependent queuing of handoff requests with 2 and 3 priority classes in PCS (2002)

An analytical framework which employs a delay-dependent queue discipline with two and three classes of priority for handoff calls is considered. The results show that, as the number of priority classes increases from two to three classes of voice traffic, the performance of dynamic priority queuing improves by 22%. In the case of mixed voice, data, and video traffic, the performance is worse than the case when only one type of traffic (e.g., voice) with different classes is considered.
Neue molekulare Gerüste: Bildung helicaler Sekundärstrukturen bei einer Gruppe von Oligoanthranilamiden (1994)

In einer einfachen Reaktionssequenz entsteht aus 2‐Nitrobenzoylchlorid, Anthranilisäuremethylester und 2,6‐Pyridindicarbonsäuredichlorid das Oligoanthranilamid 1. Es hat in Lösung und im Festkörper eine Helixstruktur, deren Ganghöhe durch Synthese des entsprechenden Pyridin‐N‐oxid‐Derivats verändert werden kann. Peptidgerüst‐Mimetica sind für das Wirkstoff‐und de‐novo‐Protein‐Design von großem Interesse. magnified image
Liquid chromatograph-mass spectrometer for analysis of nonvolatile samples (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLiquid chromatograph-mass spectrometer for analysis of nonvolatile samplesC. R. Blakley, J. J. Carmody, and M. L. VestalCite this: Anal. Chem. 1980, 52, 11, 1636–1641Publication Date (Print):September 1, 1980Publication History Published online1 May 2002Published inissue 1 September 1980https://pubs.acs.org/doi/10.1021/ac50061a025https://doi.org/10.1021/ac50061a025research-articleACS PublicationsRequest reuse permissionsArticle Views378Altmetric-Citations151LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
On the Identification of Symmetric and Antisymmetric Impulse Responses (2021)

System identification problems can be efficiently addressed by exploiting some specific characteristics of the impulse responses. In this paper, we focus on the identification of systems that own intrinsic symmetric and antisymmetric properties. Such impulse responses can be modeled based on a combination of bilinear forms, which can be further identified using customized algorithms. In this framework, we propose an iterative Wiener filter tailored for such models. As compared to the conventional Wiener filter, the iterative version is able to achieve significantly better results, especially when a small amount of data is available for the estimation of the required statistics.
Profiling of immune checkpoint biomarkers by multiplex immunofluorescence in breast cancer brain metastases. (2021)

2021 Background: Despite potential clinical implications, the complexity of immune microenvironment in breast cancer (BC) brain metastases (BM) is still poorly understood. Multiplex immunofluorescence (mIF) allows simultaneous visualization of several IF labeled proteins while maintaining spatial information. This novel technique can be used to comprehensively describe BCBM immune microenvironment, potentially providing useful information to guide novel therapeutic approaches. Methods: Clinical data and archival BM samples from 60 BC patients undergoing neurosurgery (2003-2018) at three institutions were collected. BCBMs were characterized using a custom mIF panel, including immune checkpoint and co-inhibitory molecules (CD3, PD1, PD-L1, TIM3, LAG3, CD163) and localization (keratin for tumor recognition) markers. Mean marker density was determined by digital image analysis (positive cells/mm2) and classified in tumor and stroma areas. Associations between immune marker densities, BC subtype and overall survival from BM diagnosis (OS) were studied. Results: Sixty BCBM samples were analyzed; 32% HR+/HER2-, 38% HER2+, 30% HR-/HER2-. At a median follow-up of 43 months, the only clinical variable associated with OS was BC subtype (shortest for HR-/HER2- and longest for HER2+, p=0.02). In the total sample area and tumor area, no significant difference in marker density was observed according to BC subtype. In the stroma area, a significant difference in TIM3+ cell density was observed according to BC subtype (highest density in HR+/HER2- and lowest density in HER2+ tumors, Kruskal-Wallis p=0.017). Higher CD163 density (a marker of M2 macrophage polarization), both in the tumor and in the stroma area, was significantly associated with worse OS, even after correction by BC subtype. In the subgroup of patients with HR+/HER2- BCBM, high TIM3+ cell density in the stroma area was significantly associated with longer OS (median OS 54.1 versus 23 months respectively for TIM3+ density above and below median value; p=0.01). Conclusions: In BCBM, stromal TIM3+ immune infiltrate differs according to BC subtype. M2 macrophage polarization is consistently associated with worse OS across all BC subtypes and might represent a potential therapeutic target for these patients.[Table: see text]
NaLi-H1: A universal synthetic library of humanized nanobodies providing highly functional antibodies and intrabodies (2016)

In vitro selection of antibodies allows to obtain highly functional binders, rapidly and at lower cost. Here, we describe the first fully synthetic phage display library of humanized llama single domain antibody (NaLi-H1: Nanobody Library Humanized 1). Based on a humanized synthetic single domain antibody (hs2dAb) scaffold optimized for intracellular stability, the highly diverse library provides high affinity binders without animal immunization. NaLi-H1 was screened following several selection schemes against various targets (Fluorescent proteins, actin, tubulin, p53, HP1). Conformation antibodies against active RHO GTPase were also obtained. Selected hs2dAb were used in various immunoassays and were often found to be functional intrabodies, enabling tracking or inhibition of endogenous targets. Functionalization of intrabodies allowed specific protein knockdown in living cells. Finally, direct selection against the surface of tumor cells produced hs2dAb directed against tumor-specific antigens further highlighting the potential use of this library for therapeutic applications.
Potential Target Antigens for a Universal Vaccine in Epithelial Ovarian Cancer (2010)

The prognosis of epithelial ovarian cancer (EOC), the primary cause of death from gynaecological malignancies, has only modestly improved over the last decades. Immunotherapeutic treatment using a cocktail of antigens has been proposed as a "universal" vaccine strategy. We determined the expression of tumor antigens in the context of MHC class I expression in 270 primary tumor samples using tissue microarray. Expression of tumor antigens p53, SP17, survivin, WT1, and NY-ESO-1 was observed in 120 (48.0%), 173 (68.9%), 208 (90.0%), 129 (56.3%), and 27 (11.0%) of 270 tumor specimens, respectively. In 93.2% of EOC, at least one of the investigated tumor antigens was (over)expressed. Expression of MHC class I was observed in 78.1% of EOC. In 3 out 4 primary tumors, (over)expression of a tumor antigen combined with MHC class I was observed. These results indicate that a multiepitope vaccine, comprising these antigens, could serve as a universal therapeutic vaccine for the vast majority of ovarian cancer patients.
Perovskite Solar Cells: Achieving 20% Efficiency for Low‐Temperature‐Processed Inverted Perovskite Solar Cells (Adv. Funct. Mater. 12/2019) (2019)

In article number 1807556, Takeshi Sano, Junji Kido, and co-workers demonstrate a low-temperature solution-processed TFB as an ideal hole-transporting layer to push the power conversion efficiency of one-step-processed CH3NH3PbI3-based inverted perovskite solar cells up to 20.2%. Moreover, this device shows good stability, retaining 90% of its original efficiency after storage for 30 days in ambient air.
Baeyer-Villiger-Including Domino Two-Step Oxidations of β-O-Substituted Primary Alcohols: Reflection of the Migratory Aptitudes of O-Substituted Alkyl Group in the Outcome of the Reaction (2020)

Following the recent development of the one-pot two-step oxidation protocol for primary β-alkoxy alcohols, additional primary β-oxy alcohols were examined under similar conditions. The outcome of these reactions closely follows the migratory aptitudes of the related α-oxy-alkyls in Baeyer-Villiger oxidation vs. that of hydrogen. Thus, these experiments helped to establish the correct order of these aptitudes for α-oxy-alkyls. Furthermore, in the case of primary β,β-dialkoxyalcohols, the formation of dialkoxymethyl formates by the domino oxidation reaction was followed by secondary reactions, forming a number of interesting products.
Prevalence of liver disease in cystic fibrosis. (1991)

To assess the prevalence, demography, and clinical features of liver disease among patients with cystic fibrosis the case notes of 524 patients of all ages who were attending the cystic fibrosis clinic were studied. Computer databases were used to establish the condition of the liver in a further 576 such patients. The overall prevalence of overt liver disease indicated by the presence of an enlarged liver or spleen (or both) was 4.2%. The age related prevalence rose to a peak in adolescence, and then fell in patients over 20 years old. The implied increase in mortality among those with liver disease was not explained by deaths from liver disease, which were rare. Male patients were significantly more affected than female, the ratio being 3:1 among adolescents. Increasing prevalence of liver disease in patients with cystic fibrosis is, therefore, not just a result of longevity.
Molecular Dynamics simulations of plasma sputtered ZrxCu1-x amorphous metallic glass thin film growth. Effects of composition and kinetic energy (2013)

Comm. orale
High Resolution Plane Wave Compounding Through Deep Proximal Learning (2020)

Ultra-fast ultrasound imaging relies on coherent Plane Wave (PW) compounding to obtain sufficient spatial resolution, and contrast. However, the process of coherent PW compounding incurs a loss in temporal resolution. We propose a Deep Learning (DL) network that achieves high resolution PW compounding using a reduced number of PW transmits. We embed a model based signal processing algorithm in the design of the network, which leads to better performance through the exploitation of the prior information that is now available to the network. Our proposed method outperforms two benchmark networks, yielding approximately an 8.2% improvement in PSNR, over the next best network. Aiming for an additional boost in resolution, we moreover train towards images acquired using higher transmit frequencies.
Supercollimation in photonic crystals composed of nano-scale silicon rods (2008)

Supercollimation is the diffraction-less propagation of light using the dispersion properties of specially-designed photonic crystals. We have measured supercollimation in photonic crystals composed of nano-scale rods over distances of up to one thousand lattice periods.
Data from MRI Tumor Regression Grade and Circulating Tumor DNA as Complementary Tools to Assess Response and Guide Therapy Adaptation in Rectal Cancer (2023)

&lt;div&gt;AbstractPurpose:&lt;p&gt;Response to preoperative chemo-radiotherapy (CRT) varies. We assessed whether circulating tumor DNA (ctDNA) might be an early indicator of tumor response or progression to guide therapy adaptation in rectal cancer.&lt;/p&gt;Experimental Design:&lt;p&gt;A total of 243 serial plasma samples were analyzed from 47 patients with localized rectal cancer undergoing CRT. Up to three somatic variants were tracked in plasma using droplet digital PCR. RECIST and MRI tumor regression grade (mrTRG) evaluated response. Survival analyses applied Kaplan–Meier method and Cox regression.&lt;/p&gt;Results:&lt;p&gt;ctDNA detection rates were: 74% (&lt;i&gt;n&lt;/i&gt; = 35/47) pretreatment, 21% (&lt;i&gt;n&lt;/i&gt; = 10/47) mid CRT, 21% (&lt;i&gt;n&lt;/i&gt; = 10/47) after completing CRT, and 13% (&lt;i&gt;n&lt;/i&gt; = 3/23) after surgery. ctDNA status after CRT was associated with primary tumor response by mrTRG (&lt;i&gt;P&lt;/i&gt; = 0.03). With a median follow-up of 26.4 months, metastases-free survival was shorter in patients with detectable ctDNA after completing CRT [HR 7.1; 95% confidence interval (CI), 2.4–21.5; &lt;i&gt;P&lt;/i&gt; &lt; 0.001], persistently detectable ctDNA pre and mid CRT (HR 3.8; 95% CI, 1.2–11.7; &lt;i&gt;P&lt;/i&gt; = 0.02), and pre, mid, and after CRT (HR 11.5; 95% CI, 3.3–40.4; &lt;i&gt;P&lt;/i&gt; &lt; 0.001) compared with patients with undetectable or nonpersistent ctDNA. In patients with detectable ctDNA, a fractional abundance threshold of ≥0.07% mid CRT or ≥0.13% after completing CRT predicted for metastases with 100% sensitivity and 83.3% specificity for mid CRT and 66.7% for CRT completion. All 3 patients with detectable ctDNA post-surgery relapsed compared with none of the 20 patients with undetectable ctDNA (&lt;i&gt;P&lt;/i&gt; = 0.001).&lt;/p&gt;Conclusions:&lt;p&gt;ctDNA identified patients at risk of developing metastases during the neoadjuvant period and post-surgery, and could be used to tailor treatment.&lt;/p&gt;&lt;/div&gt;
Application of Small Angle X-ray Scattering (SAXS) for Differentiation between Normal and Cancerous Breast Tissue (2005)

We were able to differentiate between normal, benign and malignant breast tissues by using energy dispersive small angle x-ray scattering.
A service‐agnostic method for predicting service metrics in real time (2017)

Summary We predict performance metrics of cloud services using statistical learning, whereby the behaviour of a system is learned from observations. Specifically, we collect device and network statistics from a cloud testbed and apply regression methods to predict, in real‐time, client‐side service metrics for video streaming and key‐value store services. Results from intensive evaluation on our testbed indicate that our method accurately predicts service metrics in real time (mean absolute error below 16% for video frame rate and read latency, for instance). Further, our method is service agnostic in the sense that it takes as input operating systems and network statistics instead of service‐specific metrics. We show that feature set reduction significantly improves the prediction accuracy in our case, while simultaneously reducing model computation time. We find that the prediction accuracy decreases when, instead of a single service, both services run on the same testbed simultaneously or when the network quality on the path between the server cluster and the client deteriorates. Finally, we discuss the design and implementation of a real‐time analytics engine, which processes streams of device statistics and service metrics from testbed sensors and produces model predictions through online learning.
A micro-transfer printed high efficiency flexible photovoltaic panel (2011)

Semprius micro transfer-prints small high efficiency solarcells to produce very low weight, flexible, and weatherized solar panels. The micro-cell design is based on a conventional lattice matched GaInP/GaAs dual junction cell epitaxially grown over a sacrificial release layer suitable for post-release transfer-printing. Solar panels with 12.8% efficiency and 280 W/Kg specific power have been fabricated. We anticipate higher performance panels with specific power over 500 W/Kg can be achieved by printing higher efficiency three junction solar cells, optimizing the cell size and process improvements to reduce lamination thickness.