gebhart/patrepeval huggingface dataset:
Perturbation Solution of an Oscillator With Periodic van der Pol Damping (1993)

Abstract We present a perturbation solution for a linear oscillator with a variable damping coefficient involving the limit cycle of the van der Pol equation (van der Pol 1926). This equation arises as the variational equation governing the stability of in-phase vibration in a pair of identical van der Pol oscillators with linear coupling. The van der Pol oscillator has served as the classic example of a limit cycle oscillator, and coupled limit cycle oscillators appear in mathematical models of self-excited systems ranging from tube rows in cross flow heat exchangers to arrays of stomates in plant leaves. As in many systems modeled by coupled oscillators, criteria for phase-locking or synchronization are of fundamental importance in understanding the dynamics. In this paper we study a simple but interesting problem consisting of a pair of identical van der Pol oscillators with linear diffusive coupling which corresponds, in the mechanical analogy, to a spring connecting the masses of the two oscillators. Intuition and earlier first-order analyses suggest that the spring will pull the two masses together causing stable in-phase locking. However, previous results of a relaxation limit study (Storti and Rand 1986) indicate that the in-phase mode is not always stable and suggest the existence of an additional stability boundary. To resolve the apparent discrepancy, we obtain a new periodic solution of the variational equation as a power series in ε, the small parameter in the sinusoidal van de Pol oscillator. This approach follows Andersen and Geer’s (1982) solution for the limit cycle of an isolated van der Pol oscillator. The coupling strength corresponding to the periodic solution of the variational equation defines an additional stability transition curve which has only been observed previously in the relaxation limit. We show that this transition curve, which provides a consistent connection between the sinusoidal and relaxation limits, is O(ε2) and could not have been delected in O(ε) analyses. We determine the analytical expression for this stability transition curve to O(ε31) and show very favorable agreement with numerical results we obtained using an Adams-Gear method.
Processing and Performance of Hydroxyapatite/Fluorapatite Double Layer Coating on Zirconia by the Powder Slurry Method (2006)

A hydroxyapatite/fluorapatite (HA/FA) double layer was coated on ZrO 2 by a powder slurry method. The FA layer between the HA layer and the ZrO 2 substrate was effective in suppressing the reaction between HA and ZrO 2 . The rheological properties of the slurry and the thermal treatment conditions were optimized. Addition of small amounts of tri‐ethyl phosphate dispersant and polyvinylbutyral binder (up to 5 wt%) was effective in reducing the slurry viscosity, even at high loadings of HA powder. Each layer (HA, FA) was deposited on ZrO 2 repeatedly to induce a uniform layer, and the final heat treatment was carried out above 1200°C to consolidate the coating layer. During this process, without the FA‐intermediate layer, a severe reaction between HA and ZrO 2 occurred to form tri‐calcium phosphate and CaZrO 3 products. However, the presence of the FA layer between HA and ZrO 2 effectively suppressed the reaction up to 1300°C. The obtained HA/FA double coating layer was micro‐porous and relatively rough, but was firmly adhered to the ZrO 2 substrate, having a bonding strength of approximately 25 MPa after heat treatment above 1200°C. The osteoblast‐like cells cultured on the HA/FA coating layer spread and proliferated favorably, having a cell proliferation rate comparable to that of a plastic control and HA bulk ceramic.
IBM Power9 Processor Architecture (2017)

The IBM Power9 processor has an enhanced core and chip architecture that provides superior thread performance and higher throughput. The core and chip architectures are optimized for emerging workloads to support the needs of next-generation computing. Multiple variants of silicon target the scale-out and scale-up markets. With a new core microarchitecture design, along with an innovative I/O fabric to support several accelerated computing requirements, the Power9 processor meets the diverse computing needs of the cognitive era and provides a platform for accelerated computing.
Supplementary Figure 6 from An <i>In Vivo</i> Immunotherapy Screen of Costimulatory Molecules Identifies Fc-OX40L as a Potent Reagent for the Treatment of Established Murine Gliomas (2023)

&lt;p&gt;PDF file, 149K, T cell expansion comparable between vaccine and vaccine/Fc-OX40L groups at early time points.&lt;/p&gt;
Chemical Control of the Octahedral Network of Solar Absorbers from the CuI-AgI-BiI3 Phase Space via the Discovery of 3D CuAgBiI5 (2021)

CuAgBiI5 is synthesised as powder, crystals, and thin films. The structure consists of a 3D octahedral Ag+/Bi3+network as in spinel but the tetrahedral interstitials occupied by Cu+ differ from those of a spinel. The 3D octahedral network of CuAgBiI5 allows us to identify a relationship between octahedral site occupancy (composition) and octahedral motif (structure) across the whole CuI-AgI-BiI3 phase field, giving the ability to chemically control structural dimensionality. To investigate composition-structure-property relationships, we explore how the basic optoelectronic properties of CuAgBiI5 compare to those of Cu2AgBiI6 (which has a 2D octahedral network) and reveal a surprisingly low sensitivity towards dimensionality of the octahedral network. The absorption onset of CuAgBiI5 (2.02 eV) barely changes compared with that of Cu2AgBiI6 (2.06 eV) indicating no obvious signs of an increase in charge confinement. Such behaviour contrasts with that for lead halide perovskites which show clear confinement effects upon lowering dimensionality of the octahedral network from 3D to 2D. Changes in PL spectra and lifetimes between the two compounds mostly derive from difference in extrinsic defect densities rather than intrinsic effects. While both materials show good stability, bulk CuAgBiI5 powder samples are found to be more sensitive degradation under solar irradiation compared to Cu2AgBiI6.
EEG spectral entropy correlates with regional cerebral blood flow during sevoflurane and propofol anesthesia (2004)

Scheinin, H.; Mäenpää, M.; Kaisti, K.; Aalto, S.; Jääskeläinen, S.; Martens, S.; Särkelä, M.; Viertiö-Oja, H. Author Information
Role of cytoplasmic localization of maspin in promoting cell invasion in breast cancer with aggressive phenotype (2021)

Mammary serine protease inhibitor (maspin) is a tumor suppressor gene that is downregulated during carcinogenesis and breast cancer progression. While the nuclear localization of maspin is essential for tumor suppression, we previously reported that the cytoplasmic localization of maspin was significantly correlated with poor prognosis in breast cancer patients. To understand the mechanisms that underlie oncogenic role of cytoplasmic maspin, we studied its biological function in breast cancer cell lines. Subcellular localization of maspin in MDA-MB-231 breast cancer cells was mainly detected in the cytoplasm, whereas in MCF10A mammary epithelial cells, maspin was present in both cytoplasm and nucleus. In MDA-MB-231 cells, maspin overexpression promoted cell proliferation and cell invasion, whereas maspin downregulation resulted in the opposite effect. Further, we observed that SRGN protein levels were increased in MDA-MB-231 cells stably overexpressing maspin. Finally, maspin overexpression in MDA-MB-231 cells resulted in the N-cadherin and epithelial mesenchymal transition (EMT)-related transcription factors upregulation, and TGFβ signaling pathway activation. These results suggested that cytoplasmic maspin enhances the invasive and metastatic potential in breast cancer cells with aggressive phenotype by inducing EMT via SRGN/TGFβ axis. This study demonstrated a novel biological function of cytoplasmic maspin in progression of breast cancer cells with an aggressive phenotype.
Unravelling Ultrafast Li Ion Transport in Functionalized Metal–Organic Framework-Based Battery Electrolytes (2023)

Nonaqueous fluidic transport and ion solvation properties under nanoscale confinement are poorly understood, especially in ion conduction for energy storage and conversion systems. Herein, metal-organic frameworks (MOFs) and aprotic electrolytes are studied as a robust platform for molecular-level insights into electrolyte behaviors in confined spaces. By employing computer simulations, along with spectroscopic and electrochemical measurements, we demonstrate several phenomena that deviate from the bulk, including modulated solvent molecular configurations, aggregated solvation structures, and tunable transport mechanisms from quasi-solid to quasi-liquid in functionalized MOFs. Technologically, taking advantage of confinement effects may prove useful for addressing stability concerns associated with volatile organic electrolytes while simultaneously endowing ultrafast transport of solvates, resulting in improved battery performance, even at extreme temperatures. The molecular-level insights presented here further our understanding of structure-property relationships of complex fluids at the nanoscale, information that can be exploited for the predictive design of more efficient electrochemical systems.
Mechanism of AlIII-Catalyzed Transamidation of Unactivated Secondary Carboxamides (2006)

The carbon-nitrogen bond of secondary carboxamides is generally thermodynamically and kinetically unreactive; however, we recently discovered that the trisamidoaluminum(III) dimer Al2(NMe2)6 catalyzes facile transamidation between simple secondary carboxamides and primary amines under moderate conditions. The present report describes kinetic and spectroscopic studies that illuminate the mechanism of this unusual transformation. The catalytic reaction exhibits a bimolecular rate law with a first-order dependence on the Al(III) and amine concentrations. No rate dependence on the carboxamide concentration is observed. Spectroscopic studies (1H and 13C NMR, FTIR) support a catalyst resting state that consists of a mixture of tris-(kappa2-amidate)aluminum(III) complexes. These results, together with the presence of a significant kinetic isotope effect when deuterated amine substrate (RND2) is used, implicate a mechanism in which the amine undergoes preequilibrium coordination to aluminum and proton transfer to a kappa2-amidate ligand to yield an Al(kappa2-amidate)2(kappa1-carboxamide)(NHR) complex, followed by rate-limiting intramolecular delivery of the amido ligand (NHR) to the neutral Al(III)-activated kappa1-carboxamide. Noteworthy in this mechanism is the bifunctional character of Al(III), which is capable of activating both the amine nucleophile and the carboxamide electrophile in the reaction.
Characterization of surface mobility on the sidewalls of dry-etched trenches (2003)

The mobility on the sidewalls of the etched trenches was measured for electrons and holes for two surface orientation, for two different trench etch processes, and for various post-etch treatments. It was found that the dry etch process decreases the mobility of electrons for both processors and orientations and for all post-etch treatments. However, hole mobility is not reduced significantly by the dry etch processes. It is proposed that atomic scale surface roughness is the cause of the electron mobility reduction. Holes seem to be more immune to these surface roughness effects; thus the mobility is not significantly reduced by the dry etch process. Moreover, because of quantization and effective mass considerations, the hole mobility on
On filter banks with rational oversampling (2002)

Despite the great popularity of critically-decimated filter banks, oversampled filter banks are useful in applications where data expansion is not a problem. We studied oversampled filter banks and showed that for some popular classes of filter banks it is not possible to obtain perfect reconstruction with rational (non-integer) oversampling ratios. Nevertheless, it is always possible to oversample the analysis filter bank by an integer factor, ie, there will be a similar synthesis bank which would provide perfect reconstruction. The analysis is carried within a time-aliasing framework development to analyze non-critically decimated filter banks.
Introduction to Applications for Thermal Spray Processing (2013)

Abstract This article describes the process of selecting an optimum coating and material system for a specific application. It reviews critical coating functions that influence the coating selection process, and presents some application success stories. The article explores the benefits of thermal spray coatings and functions they provide. It also presents key references from various National Thermal Spray Conference, United Thermal Spray Conference, and International Thermal Spray Conference Proceedings from 2006 through 2012.
List Of African Countries And Capitals (2018)

The list of African countries and capitals begins with Algeria with the capital of Algiers and ends with Zimbabwe with the capital of Harare. The 54 countries in Africa speak an estimated 1,500 to 2,000 languages and is believed to be the origin of humans. How many African countries can you name? And do you know
Process for the synthesis of perfluoroalkylethers (2007)

Perfluoro ethers Rf-O-CX1X2-CX3X4-F are prepd. by addn. reaction of perfluorinated hypofluorites RfOF with perfluoroolefins CX1X2:CX3X4. The process is characterized by a molar ratio of hypofluorite to olefin in the reaction medium which is greater than unity. In the above formulas, Rf is linear or branched C1-5 perfluoroalkyl or perfluoro(oxy)alkylene contg. at least one O atom and optionally an SO2F or COF group; X1-4 are independently F or ORf. For example, a flow of 3.3 N L/h CF3OF dild. with 6.6 N L/h He and a flow of 3.0 N L/h CF3OCF:CF2 were directed into CFC 316 (100 g) at -60 for 7 h, followed by flushing of excess CF3OF with 3.3 N L/h He for 30 min, to show a 99.6% yield of addn. products, these being the desired CF3OCF2CF2OCF3 and the undesired (CF3O)2CFCF3, with a selectivity of 99.9%. In a comparison example, where the flow of both reactants was 3.3 N L/h, selectivity for the desired isomer dropped to 71.2%. In a similar example using CF2:CF2 as the olefin, selectivity for CF3OCF2CF3 over dimerization and polymn. products was likewise improved, from 48.3% with a slight excess of olefin, to 99.3% using an excess of hypofluorite according to the invention.
History of Safety Research and Development on the General Motors Energy-Absorbing Steering System (1991)

&lt;div class="htmlview paragraph"&gt;This paper covers the development of the General Motors Energy Absorbing Steering System beginning with the work of the early crash injury pioneers Hugh DeHaven and Colonel John P. Stapp through developments and introduction of the General Motors energy absorbing steering system in 1966. evaluations of crash performance of the system, and further improvement in protective function of the steering assembly. The contributions of GM Research Laboratories are highlighted, including its safety research program. Safety Car, Invertube, the biomechanic projects at Wayne State University, and the thoracic and abdominal tolerance studies that lead to the development of the Viscous Injury Criterion and self-aligning steering wheel. Also discussed are engineering efforts of the Saginaw Steering Gear and Oldsmobile Divisions. the extensive testing program at the GM Proving Ground, government interactions and regulations, and the field accident reports of the many lives saved by Energy Absorbing Steering Systems.&lt;/div&gt;
A new flash E<sup>2</sup>PROM cell using triple polysilicon technology (1984)

A new Flash Electrically Erasable-PROM cell with single transistor per bit as same as conventional UV-EPROM(1) (2) and suitable for 256K bit F-E <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> PROM with rather conservative 2.0µm design rule is described. The cell is programmed by a channel hot carrier injection mechanism similar to EPROM. The contents of all memory cells are simultaneously erased by using field emission of electrons from a floating gate to an erase gate in a flash. The F-E <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> PROM cell with single transistor per bit consists of three layers of polysilicon with select transistor. (3) (4) (5) Programming is 10msec per bit as same as UV-EPROM. Good erasing characteristics is obtained with 550Å of oxide thickness between floating gate and erase gate.
Single Glucose Biofuel Cells Implanted in Rats Power Electronic Devices (2013)

We describe the first implanted glucose biofuel cell (GBFC) that is capable of generating sufficient power from a mammal's body fluids to act as the sole power source for electronic devices. This GBFC is based on carbon nanotube/enzyme electrodes, which utilize glucose oxidase for glucose oxidation and laccase for dioxygen reduction. The GBFC, implanted in the abdominal cavity of a rat, produces an average open-circuit voltage of 0.57 V. This implanted GBFC delivered a power output of 38.7 μW, which corresponded to a power density of 193.5 μW cm(-2) and a volumetric power of 161 μW mL(-1). We demonstrate that one single implanted enzymatic GBFC can power a light-emitting diode (LED), or a digital thermometer. In addition, no signs of rejection or inflammation were observed after 110 days implantation in the rat.
Time-resolved optical measurements of minority carrier recombination in a mid-wave infrared InAsSb alloy and InAs/InAsSb superlattice (2012)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation B. V. Olson, E. A. Shaner, J. K. Kim, J. F. Klem, S. D. Hawkins, L. M. Murray, J. P. Prineas, M. E. Flatté, T. F. Boggess; Time-resolved optical measurements of minority carrier recombination in a mid-wave infrared InAsSb alloy and InAs/InAsSb superlattice. Appl. Phys. Lett. 27 August 2012; 101 (9): 092109. https://doi.org/10.1063/1.4749842 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioApplied Physics Letters Search Advanced Search |Citation Search
Virus-Like Particle Vaccination Protects Nonhuman Primates from Lethal Aerosol Exposure with Marburgvirus (VLP Vaccination Protects Macaques against Aerosol Challenges) (2016)

Marburg virus (MARV) was the first filovirus to be identified following an outbreak of viral hemorrhagic fever disease in Marburg, Germany in 1967. Due to several factors inherent to filoviruses, they are considered a potential bioweapon that could be disseminated via an aerosol route. Previous studies demonstrated that MARV virus-like particles (VLPs) containing the glycoprotein (GP), matrix protein VP40 and nucleoprotein (NP) generated using a baculovirus/insect cell expression system could protect macaques from subcutaneous (SQ) challenge with multiple species of marburgviruses. In the current study, the protective efficacy of the MARV VLPs in conjunction with two different adjuvants: QS-21, a saponin derivative, and poly I:C against homologous aerosol challenge was assessed in cynomolgus macaques. Antibody responses against the GP antigen were equivalent in all groups receiving MARV VLPs irrespective of the adjuvant; adjuvant only-vaccinated macaques did not demonstrate appreciable antibody responses. All macaques were subsequently challenged with lethal doses of MARV via aerosol or SQ as a positive control. All MARV VLP-vaccinated macaques survived either aerosol or SQ challenge while animals administered adjuvant only exhibited clinical signs and lesions consistent with MARV disease and were euthanized after meeting the predetermined criteria. Therefore, MARV VLPs induce IgG antibodies recognizing MARV GP and VP40 and protect cynomolgus macaques from an otherwise lethal aerosol exposure with MARV.
Towards industrial applications of graphene electrodes (2012)

Since the first isolation of graphene in 2004 by mechanical exfoliation from graphite, many people have tried to synthesize large-scale graphene using various chemical methods. In particular, there has been a great number of advances in the synthesis of graphene using chemical vapor deposition (CVD) on metal substrates such as Ni and Cu. Recently, a method to synthesize ultra-large-scale (similar to 30 inch) graphene films using roll-to-roll transfer and chemical doping processes was developed that shows excellent electrical and physical properties suitable for practical applications on a large scale. Considering the outstanding scalability/processibility of roll-to-roll and CVD methods as well as the extraordinary flexibility/conductivity of graphene films, we expect that transparent graphene electrodes can replace indium tin oxide in the near future.
Gonadal Function in Survivors After Hodgkin Lymphoma (HL) Treatment within the German Hodgkin Study Group (GHSG) HD13–15 Trials. (2012)

Abstract Abstract 2636 Purpose: To improve fertility advice in HL patients before treatment and counseling during survivorship, detailed information on the impact of chemotherapy is needed. Therefore, we analyzed gonadal function in survivors after treatment of early favorable, early unfavorable and advanced stage HL. Methods: Women &lt;40 years and men &lt;50 years at diagnosis in ongoing remission at least one year after treatment within the GHSG HD13–15 trials were included. Hormone parameters, menstrual cycle, symptoms of hypogonadism, measures to preserve fertility, pregnancies, and offspring were evaluated. Results: A total of 1,323 (55%) of 2,412 contacted female and male survivors were evaluable for the current analysis. In women and men, mean age at fertility assessment was 32 and 38 years and mean observation time from the end of treatment was 46 and 48 months, respectively. Comparison of the participating and non-participating patients qualifying for our analysis showed no relevant differences. Hormone levels correlated significantly with therapy intensity (p&lt;.001). After 6–8 cycles BEACOPP (bleomycin, etoposide, adriamycin, cyclophosphamide, vincristine, procarbazine, prednisone), mean Anti-Muellerian hormone (AMH) levels in females were 0μg/l and 88.8% of males had Follicle-stimulating hormone (FSH) and inhibin B levels corresponding to oligospermia. Furthermore, low birth rates were observed in survivors after advanced-stage treatment within the observation time (women: 6.5%, men: 3.3%). Regular menstrual cycle was reported by &gt;90% of early-stage HL female survivors and time to resumption of menstrual activity was mostly reached within one year. After advanced-stage treatment, menstrual activity was strongly related to age. 82% of women younger than 30 years had a regular cycle, compared to only 45% in the older age group (p&lt;.001) and time to recovery was considerably longer than in early-stage patients. 34% of women &gt;30 years suffered severe menopausal symptoms (3–4 fold more frequently than expected). In contrast, male survivors had mean levels of testosterone within the normal range and reported no increased symptoms of hypogonadism. Conclusions: The present analysis in a large group of female and male HL survivors provides well-grounded information on gonadal toxicity of the currently used treatment regimens. Accordingly, the results allow a risk adapted planning of fertility preservation before therapy and a comprehensive support during survivorship. Disclosures: No relevant conflicts of interest to declare.