gebhart/patrepeval huggingface dataset:
Laying the Groundwork for a Worker-Centric Peer Economy (2018)

The "gig economy" has transformed the ways in which people work, but in many ways these markets stifle the growth of workers and the autonomy and protections that workers have grown to expect. We explored the viability of a "worker centric peer economy"--a system wherein workers benefit as well as consumers-- and conducted ethnographic field work across fields ranging from domestic labor to home health care. We discovered seven facets that system designers ought to consider when designing a labor market for "gig workers," consisting principally of the following: constructive feedback, assigning work fairly, managing customer expectations, protecting vulnerable workers, reconciling worker identities, assessing worker qualifications, &amp; communicating worker quality. We discuss these considerations and provide guidance toward the design of a mutually beneficial market for gig workers.
Rearrangement of 1D Conducting Nanomaterials towards Highly Electrically Conducting Nanocomposite Fibres for Electronic Textiles (2015)

Nanocarbon-based conducting fibres have been produced using solution- or dry-spinning techniques. Highly conductive polymer-composite fibres containing large amounts of conducting nanomaterials have not been produced without dispersants, however, because of the severe aggregation of conducting materials in high-concentration colloidal solutions. Here we show that highly conductive (electrical conductivity ~1.5 × 10(5) S m(-1)) polymer-composite fibres containing carbon nanotubes and silver nanowires can be fabricated via a conventional solution-spinning process without any other treatment. Spinning dopes were fabricated by a simple mixing of a polyvinyl alcohol solution in dimethylsulfoxide with a paste of long multi-walled carbon nanotubes dispersed in organic solvents, assisted by quadruple hydrogen-bonding networks and an aqueous silver nanowire dispersion. The high electrical conductivity of the fibre was achieved by rearrangement of silver nanowires towards the fibre skin during coagulation because of the selective favourable interaction between the silver nanowires and coagulation solvents. The prepared conducting fibres provide applications in electronic textiles such as a textile interconnector of light emitting diodes, flexible textile heaters, and touch gloves for capacitive touch sensors.
Multipath interference canceller for high-speed packet transmission with adaptive modulation and coding scheme in W-CDMA forward link (2002)

This paper proposes a multipath interference canceller (MPIC) associated with orthogonal code-multiplexing that achieves much higher peak throughput than 2 Mbit/s with adaptive data modulation for high-speed packet transmission in the wideband direct sequence-code division multiple access (W-CDMA) forward link, and evaluates its throughput performance by computer simulation. The simulation results elucidate that sufficient multipath interference (MPI) suppression is achieved by a four-stage MPIC with 6-12 orthogonal code-multiplexing using one iterative channel estimation with pilot and decision feedback data symbols and further that the interference rejection weight control according to the number of observed multipaths is effective in improving the throughput. It is also demonstrated that MPIC exhibits a superior MPI suppression effect to a chip equalizer in the lower received signal energy per bit-to-background noise spectrum density (E/sub b//N/sub 0/) channel around 0-3 dB owing to the successive channel estimation at each stage. We show that the maximum peak throughput using MPIC is approximately 2.1 fold that without MPIC in a two-path and three-path Rayleigh fading channel and that the peak throughput of 8.0 Mbit/s is achieved using 64 QAM data modulation in a two-path fading channel within a 5 MHz bandwidth. Furthermore, the required average E/sub b//N/sub 0/ for satisfying the same throughput with MPIC is decreased by more than 2.0 dB.
40 GHz all-optical XOR with UNI gate (2002)

40 GHz Boolean XOR is demonstrated using an ultrafast nonlinear interferometer (UNI) gate. The gate operates with low switching energy and signals from the same source. It may be used in networking applications without wavelength conversion.
Mapping key agricultural sources of dust emissions within the Lake Simcoe airshed (2013)

A decline in water quality attributed to excessive inputs of phosphorus has been observed in Lake Simcoe over the past few decades. Various studies have estimated that 25–50% of the total phosphorus entering the lake is from atmospheric deposition. Bare soil exposure in the spring due to lack of vegetative cover, along with soil disturbance related to agricultural activities, results in higher susceptibility to wind erosion and dust emission. This study introduces the new concept of Dust Response Units (DRUs), which combine soil type and land use to determine the dust emission susceptibility based on the hourly variation of wind speed and monthly changes in soil cover due to crop growth. The Wind Erosion Prediction System (WEPS) was used to determine dust emission suppression factors for a combination of 11 different soils and 6 dominant agricultural land uses, totaling 66 different DRUs in the Lake Simcoe airshed. Employing a widely used dust emission model and applying these dust emission suppression factors resulted in the identification of high risk DRUs. Twelve of the potential 66 DRUs were determined to contribute 85% of the total crop dust emissions within the Lake Simcoe airshed, including sand, loam, sandy loam, and loamy sand soils combined with row crop, mixed, and hay and pasture land management operations. This study demonstrates a new method to map high priority areas for targeted implementation of dust control best management practices that could be useful in agricultural areas both within and beyond the Lake Simcoe airshed
A hybrid access model for storage area networks (2005)

We present HSAN & a hybrid storage area network, which uses both in-band (like NFS (R. Sandberg et al., 1985)) and out-of-band visualization (like SAN FS (J. Menon et al., 2003)) access models. HSAN uses hybrid servers that can serve as both metadata and NAS servers to intelligently decide the access model per each request, based on the characteristics of requested data. This is in contrast to existing efforts that merely provide concurrent support for both models and do not exploit model appropriateness for requested data. The HSAN hybrid model is implemented using low overhead cache-admission and cache-replacement schemes and aims to improve overall response times for a wide variety of workloads. Preliminary analysis of the hybrid model indicates performance improvements over both models.
H2O2-Dependent Fe-Catalyzed Oxidations: Control of the Active Species (2001)

Manipulation of the coordination sphere of an FeII ion can be used to tune the balance between different catalytic pathways for oxidation (OH. versus iron-based oxidant; see scheme). This reinvestigation of Fenton chemistry uses the iron complex shown as a mechanistic probe.
MOLLI T1 mapping versus T2 W-SPAIR at 3T: myocardial area at risk measurements and the influence of microvascular obstruction (2014)

Funding Information: This study was supported by a Medical Research Council (UK) grant, as a sub-study of Nitrites in Acute Myocardial Infarction, NCT01388504.
Supplementary Figure 4 from PlGF/VEGFR-1 Signaling Promotes Macrophage Polarization and Accelerated Tumor Progression in Obesity (2023)

&lt;p&gt;Effects of VEGFR-1 signaling ablation on body weight gain, immune cell infiltration and vasculature in adipose tissues during obesity.&lt;/p&gt;
DNA Repair Inhibitors: The Next Major Step to Improve Cancer Therapy (2012)

Modern cancer therapies, mainly ionizing radiation and certain classes of chemotherapies target DNA. Although these treatments disrupt the genome, their rationale is clear. They prevent cancer cells from dividing and proliferating. Nevertheless, cancer cells can survive by over-activating a wide range of DNA repair pathways to eliminate the induced damage. In this context, DNA repair mechanisms are considered to be a vital target to improve cancer therapy and reduce the resistance to many DNA damaging agents currently in use as standard-of-care treatments. Here, we focus on two important DNA repair pathways, namely base excision repair (BER) and nucleotide excision repair (NER). Specifically, our focus is on two protein targets that are linked to the hallmark "relapse" and "drug resistance" phenomena. These are Excision Repair Cross-Complementation Group 1 (ERCC1), and DNA polymerase beta (pol β). The former is a key player in NER, while the latter is the error-prone polymerase of BER. Our objective is to list all known inhibitors for the two targets and provide an overview of the great efforts that were made in their discovery. While in the DNA pol β case more than sixty inhibitors were identified, very few inhibitors have been discovered on the ERCC1 side. It is hoped that this review will assist in the discovery of novel, potent and specific drug candidates aimed at improving existing cancer therapies including ionizing radiation, bleomycin, monofunctional alkylating agents and cisplatin.
ChemInform Abstract: Asymmetric Hydrogenation of Ketones with H2 and Ruthenium Catalysts Containing Chiral Tetradentate S2N2 Ligands. (2014)

Abstract The first phosphorus‐free, air‐ and moisture‐tolerant Ruthenium‐catalyzed asymmetric hydrogenation of methylketones and cyclic ketones, as well as aldehydes using hydrogen is presented.
Serological profiling of the EBV immune response in Chronic Fatigue Syndrome using a peptide microarray (2017)

Patients with CFS had a quite similar EBV IgG antibody response pattern as healthy controls. Enhanced IgG reactivity against an EBNA-6 repeat sequence and against EBNA-6 protein is found in CFS patients. Homologous sequences of various human proteins with this EBNA-6 repeat sequence might be potential targets for antigenic mimicry.
Proteomic analysis of adipocyte differentiation: Evidence that α2 macroglobulin is involved in the adipose conversion of 3T3 L1 preadipocytes (2004)

Adipogenesis is an important aspect of energy homeostasis. Here we have used a differential proteome mapping strategy to identify intracellular proteins that are differentially expressed during adipose conversion of 3T3 L1 preadipocytes. Two-dimensional gel electrophoresis analysis identified 8 proteins that are induced following hormone-evoked differentiation. In addition, we found that a alpha2 macroglobulin fragment was abundantly present in 3T3 L1 preadipocytes, but was virtually undetectable in fully differentiated adipocytes. Metabolic radiolabeling with (35S)methionine and Northern blot analysis indicated that the intracellular alpha2 macroglobulin fragment in preadipocytes was derived from the extracellular culture medium, not de novo synthesis. Incubation of preadipocytes with an antialpha2 macroglobulin polyclonal antibody caused depletion of the intracellular alpha2 macroglobulin fragments, and also enhanced spontaneous adipose conversion. These results suggest that intracellular alpha2 macroglobulin fragment inhibits adipocyte differentiation, and that hormone treatment induces differentiation at least in part by suppression of intracellular alpha2 macroglobulin activity in 3T3 L1 preadipocytes.
Modified technique for improving tubeless cutaneous ureterostomy by Ariyoshi method (2008)

The presented cutaneous ureterostomy technique to preserve the fascia is useful not only to prevent stomal stenosis and maintaining good quality of life without catheterization, but also to apply to other types of ureter surgery.
Preclinical characterization of alginate-Poly-L-Lysine encapsulated HepaRG for extracorporeal liver supply (2020)

We recently demonstrated that HepaRG cells encapsulated into 1.5% alginate beads are capable of self-assembling into spheroids. They adequately differentiate into hepatocyte-like cells, with hepatic features observed at day 14 post-encapsulation required for external bioartificial liver applications. Preliminary investigations performed within a bioreactor under shear stress conditions and using a culture medium mimicking acute liver failure (ALF) highlighted the need to reinforce beads with a polymer coating. We demonstrated in a first step that a Poly-L-Lysine coating improved the mechanical stability, without altering the metabolic activities necessary for bioartificial liver applications (such as ammonia and lactate elimination). In a second step, we tested the optimized biomass in a newly-designed perfused dynamic bioreactor (PDB), in the presence of the medium model for pathological plasma for 6 hours. Performances of the biomass were enhanced as compared to the steady configuration, demonstrating its efficacy in decreasing the typical toxins of ALF. This type of bioreactor is easy to scale up as it relies on the number of micro-encapsulated cells, and could provide an adequate hepatic biomass for liver supply. Its design allows it to be integrated into a hybrid artificial/bioartificial liver setup for further clinical studies regarding its impact on ALF animal models.
Protein and Peptide Release from in Situ Gelling Polymer (2006)

ADVERTISEMENT RETURN TO ISSUEPREVNoteProtein and Peptide Release from in Situ Gelling PolymerMichal Y. Krasko, Neeraj Kumar, and Abraham J. DombView Author Information Department of Medicinal Chemistry and Natural Products, School of Pharmacy − Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem-91120, Israel, and Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Sector 67, S.A.S. Nagar (Mohali)-160 062, India Cite this: Biomacromolecules 2006, 7, 8, 2461–2463Publication Date (Web):June 29, 2006Publication History Received19 March 2006Revised9 May 2006Published online29 June 2006Published inissue 1 August 2006https://pubs.acs.org/doi/10.1021/bm060255qhttps://doi.org/10.1021/bm060255qbrief-reportACS PublicationsCopyright © 2006 American Chemical SocietyRequest reuse permissionsArticle Views298Altmetric-Citations9LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Drug delivery,Drug release,Hydrophobicity,Peptides and proteins,Polymers Get e-Alerts
Photon statistics of pulsed parametric light (1998)

Abstract We calculate and measure the photon statistics of weak light pulses emitted in the process of pulsed parametric down-conversion. We find photon bunching as expected from a chaotic light source when viewed through a narrow-band filter.
Surface Preparation and Passivation of III-V Substrates for Future Ultra-High Speed, Low Power Logic Applications (2009)

III-V compound semiconductors have been recognized among the potential options for continuing transistor power-performance scaling owing to their ultra high charge carrier mobility. In order to realize their potential in high performance and lower-power digital logic applications, there must be strong gate control and a high Ion-Ioff ratio, achieved by integrating a stable, ultra thin high-K dielectric between the semiconductor and the gate [1, 2]. Unlike Si, which has long benefited from its very stable native oxide, III-V materials suffer from their poor native oxides that cause charge traps and Fermi level pinning at the semiconductor-oxide interface. Attempts to deposit high-K directly on III-V often produce MIS structures with fast surface state and CV instability [3].
Functional interaction of Fas‐associated phosphatase‐1 (FAP‐1) with p75NTR and their effect on NF‐κB activation (1999)

The common neurotrophin receptor p75(NTR), a member of the tumor necrosis factor (TNF) receptor superfamily, plays an important role in several cellular signaling cascades, including that leading to apoptosis. FAP-1 (Fas-associated phosphatase-1), which binds to the cytoplasmic tail of Fas, was originally identified as a negative regulator of Fas-mediated apoptosis. Here we have shown by co-immunoprecipitation that FAP-1 also binds to the p75(NTR) cytoplasmic domain in vivo through the interaction between the third PDZ domain of FAP-1 and C-terminal Ser-Pro-Val residues of p75(NTR). Furthermore, cells expressing a FAP-1/green fluorescent protein showed intracellular co-localization of FAP-1 and p75(NTR) at the plasma membrane. To elucidate the functional role of this physical interaction, we examined TRAF6 (TNF receptor-associated factor 6)-mediated NF-kappaB activation and tamoxifen-induced apoptosis in 293T cells expressing p75(NTR). The results revealed that TRAF6-mediated NF-kappaB activation was suppressed by p75(NTR) and that the p75(NTR)-mediated NF-kappaB suppression was reduced by FAP-1 expression. Interestingly, a mutant of the p75(NTR) intracellular domain with a single substitution of a Met for Val in its C-terminus, which cannot interact with FAP-1, displayed enhanced pro-apoptotic activity in 293T transfected cells. Thus, similar to Fas, FAP-1 may be involved in suppressing p75(NTR)-mediated pro-apoptotic signaling through its interaction with three C-terminal amino acids (tSPV). Thus, FAP-1 may regulate p75(NTR)-mediated signal transduction by physiological interaction through its third PDZ domain.
The Seven Thousand Cadres Conference (1997)

Abstract This chapter examines the when, why, and how of the CCP's Seven Thousand Cadres Conference, held from January 11 to February 7, 1962. The conference was called as such because of the number of attendees, which included political leaders and representatives from districts, counties, and industrial enterprises. The origins of the conference were due to a watershed in the post-GLF reform process, and the political atmosphere at the event enabled policy proposals drawn up in 1961 to be seriously implemented.
Effects of Partially Hydrogenated, Semi‐Saturated, and High Oleate Vegetable Oils on Inflammatory Markers and Lipids (2010)

Knowledge about the effects of dietary fats on subclinical inflammation and cardiovascular disease risk are mainly derived from studies conducted in Western populations. Little information is available on South East Asian countries. This current study investigated the chronic effects on serum inflammatory markers, lipids, and lipoproteins of three vegetable oils. Healthy, normolipidemic subjects (n = 41; 33 females, 8 males) completed a randomized, single-blind, crossover study. The subjects consumed high oleic palm olein (HOPO diet: 15% of energy 18:1n-9, 9% of energy 16:0), partially hydrogenated soybean oil (PHSO diet: 7% of energy 18:1n-9, 10% of energy 18:1 trans) and an unhydrogenated palm stearin (PST diet: 11% of energy 18:1n-9, 14% of energy 16:0). Each dietary period lasted 5 weeks with a 7 days washout period. The PHSO diet significantly increased serum concentrations of high sensitivity C-reactive protein compared to HOPO and PST diets (by 26, 23%, respectively; P < 0.05 for both) and significantly decreased interleukin-8 (IL-8) compared to PST diet (by 12%; P < 0.05). In particular PHSO diet, and also PST diet, significantly increased total:HDL cholesterol ratio compared to HOPO diet (by 23, 13%, respectively; P < 0.05), with the PST diet having a lesser effect than the PHSO diet (by 8%; P < 0.05). The use of vegetable oils in their natural state might be preferred over one that undergoes the process of hydrogenation in modulating blood lipids and inflammation.
Hashing on strings, cryptography, and protection of privacy (1997)

Summary form only given. The issues of privacy and reliability of personal data are of paramount importance. If L is a list of people carrying some harmful defective gene, we want questions as to whether a person is in L to be reliably answered without compromising the data concerning anybody else. Reliability means that once the list is formed, nobody can play with the answer. Thus the answer should be checkable by the agent posing the question. We present an efficient protocol for this task. Our solution has very strong privacy protection properties.
Ethyl 2-((4-Chlorophenyl)amino)thiazole-4-carboxylate and Derivatives Are Potent Inducers of Oct3/4 (2015)

The octamer-binding transcription factor 4 (Oct3/4) is a master gene in the transcriptional regulatory network of pluripotent cells. Repression of Oct3/4 in embryonic stem cells (ESCs) is associated with cell differentiation and loss of pluripotency, whereas forced overexpression in cooperation with other transcriptional factors, such as Nanog, Sox2, and Lin28, can reprogram somatic cells back into pluripotent cells, termed induced pluripotent stem cells (iPSCs). However, random integration and potential tumorigenic transformation caused by viral transduction limit the clinical application of iPSCs. By performing a cell-based high throughput screening (HTS) campaign, we identified several potential small molecules as inducers of Oct3/4 expression. Here we report a lead structure ethyl 2-((4-chlorophenyl)amino)-thiazole-4-carboxylate, termed O4I2, showing high activity in enforcing Oct3/4 expression. On the basis of chemical expansion, we further identified derivatives having increased activities toward Oct3/4 induction. Thus, O4I2 and its derivatives should provide a new class of small molecules suitable for iPSC generation.
Heuristic Dynamic Programming for Adaptive Virtual Synchronous Generators (2019)

In this paper a neural network heuristic dynamic programing (HDP) is used for optimal control of the virtual inertia-based control of grid connected three-phase inverters. It is shown that the conventional virtual inertia controllers are not suited for non-inductive grids. A neural network-based controller is proposed to adapt to any impedance angle. Applying an adaptive dynamic programming controller instead of a supervised controlled method enables the system to adjust itself to different conditions. The proposed HDP consists of two subnetworks: critic network and action network. These networks can be trained during the same training cycle to decrease the training time. The simulation results confirm that the proposed neural network HDP controller performs better than the traditional direct-fed voltage and/or reactive power controllers in virtual inertia control schemes.