gebhart/patrepeval huggingface dataset:
Numerical Evaluation of Performance Curves of a High Frequency Microcompressor (2012)

This work presents a methodology for the numerical simulation of reed valves of a small-size reciprocating compressor (approximately 200 mm in length, 60 mm in diameter), oil free and operating at high frequency. A fluidstructure interaction methodology is employed, where the fluid domain is modeled by the tridimensional transient Navier-Stokes equations, while the solid domain is governed by a beam model considering geometrical contacts between valves and stoppers (valve plate, piston, etc.) Results are shown for mass flow, pump power consumption and valve losses for evaporating temperatures ranging from -15 degrees Celsius to +40 degrees Celsius, and condensing temperatures from +45 degrees Celsius to +85 degrees Celsius. Finally, numerical results were compared to experimental data.
Increasing Ionic Conductivity of Poly(ethylene oxide) by Reaction with Metallic Li (2021)

Poly(ethylene oxide) (PEO) was the first lithium‐ion conducting polymer developed 50 years ago and is still the most popular electrolyte matrix for solid‐state lithium metal batteries. While many studies focus on increasing PEO ionic conductivity through doping with Li salts, little work has addressed using PEO and Li directly to generate Li + ‐conducting species in situ. Reaction between PEO and Li leads to ionic conductivity largely from Li + , in contrast to the case of added salts where the anion contribution dominates. Herein, electrochemical impedance spectroscopy shows the ionic conductivity of PEO thin films increases up to three orders of magnitude (from 10 −7 to 10 −4 S cm −1 ) when contacted with Li at elevated temperature. This is due to the reduction of ether bonds, which produces lithium alkoxides that are responsible for Li + transport. Density functional theory analysis confirms this mechanism as thermodynamically favorable. X‐ray photoelectron spectroscopy also shows the presence of organolithium species and Li 2 O, which are responsible for propagating reactions with PEO and forming an electronically insulating layer at the PEO–Li interface that halts further reaction, respectively. The underlying mechanisms of Li–polymer electrolyte reactions is clarified and new pathways for in situ Li + doping of polymer electrolytes is presented.
Supplementary Fig. S6 from Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies (2023)

&lt;p&gt;16DCRPC cell line variants expressing BCL-2 and IKKB are resistant to ENZ&lt;/p&gt;
Mediating Group Dynamics through Tabletop Interface Design (2006)

A Stanford University research group explores how design alternatives for tabletop interfaces can impact group dynamics to promote effective teamwork. They built and evaluated a series of novel prototypes that explore Multi-User Coordination Policies and cooperative gesturing, encouraging equitable participation in educational tasks and supporting social skills development for special-needs populations.
ChemInform Abstract: Axinellis A and B: New Proline‐Containing Antiproliferative Cyclopeptides from the Vanuatu Sponge Axinella carteri. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Multiview video coding using projective rectification-based view extrapolation and synthesis bias correction (2009)

Current view synthesis prediction (VSP) techniques for multiview video coding (MVC) rely on disparity-based view interpolation or depth-based 3D warping. The former cannot be applied to every camera view, whereas the latter may require coding of the depth information of a scene. To avoid these constraints, we propose an improved VSP-based MVC scheme based on the following three techniques: 1) view extrapolation, which allows VSP to be applicable to almost all camera views, 2) projective rectification, which improves the synthesis quality when neighboring camera planes are not parallel, and 3) synthesis bias correction, which uses the past synthesis biases to improve the synthesis quality of the current frame. Experimental results demonstrate that our scheme offers PSNR gains of up to 1.6 dB compared to the current MVC standard.
Rare Bisindole Alkaloids from the Amazonian Tree Raputia simulans (2014)

The stem bark of Raputia simulans (Rutaceae) has been reported to contain simple and dimeric indole alkaloids. Further phytochemical investigation of R. simulans stem bark resulted in the isolation of three new alkaloids. These compounds represent a relatively new category of dimeric indole alkaloids with a cyclohexene moiety in their core. Their structure elucidations were based on NMR and HR-MS techniques, while structural aspects concerning their relative configuration were investigated using molecular mechanics calculations and NOESY experiments.
waveguides for integrated magneto-optical isolator applications (2010)

Sr(Ti0.6Fe0.4)O3 (STF) and Sr(Ti0.7Co0.3)O3 (STC) room-temperature ferromagnetic oxides were grown epitaxially on LaAlO3(001), (LaSr)(AlTa)O3 (001) and Si (001) substrates. Both materials were demonstrated to be magneto-optically active, and more optically transparent at 1550nm wavelength compared with other non-garnet ferromagnetic materials. As2S3/STF and As2S3/STC strip-loaded waveguides were fabricated on epitaxial STF or STC films grown on LSAT (001) substrates using thermal evaporation and lift-off processing. The absorption of STF at 1550 nm was measured by ellipsometry and by optical transmission spectrum measurements of the As2S3/STF waveguides, which gave similar results. A novel design for a Non-Reciprocal Phase Shift (NRPS) strip-loaded waveguide using chalcogenide glass (ChG) as the guiding layer is proposed. The NRPS and figure of merit of these waveguides are simulated. The ChG strip-loaded waveguide structure shows advantages both in fabrication and device performance according to the simulation results. Our study suggests the possibility of magneto-optical magneto-optical isolators monolithically integrated on a silicon platform.
Synthesis of 2-Pyrrolidinol Metabolite of OPC-51803, a Vasopressin V2 Receptor Agonist (2003)

The unstable 2-pyrrolidinol derivative (2), as a metabolite of a new vasopressin V 2 receptor agonist OPC-51803 (1), was synthesized by the cytochrome P-450 model reaction of 1 with the Fe-salen complex and iodosobenzene.
Band to band hopping in one-dimensional maps (1981)

One-dimensional maps have chaotic bands which may merge at critical values of the control parameter, a. Just after the merger, one can define a band-to-band hopping time, which diverges as mod a-ac mod -1z/ for a map with a zth-order maximum. Numerical data are presented to support this conclusion.
Membrane Proteomics of Impaired Energetics and Cytoskeletal Disorganization in Elderly Diet-Induced Diabetic Mice (2017)

Diabetic cardiomyopathy is a well-recognized complication of diabetes, but its pathophysiology is unclear. We aimed to investigate the mechanisms underlying cardiac dysfunction in an elderly type 2 diabetic (T2DM) mouse model, using membrane proteomic analyses. Elderly mice were fed a high fat diet for 12 weeks to induce T2DM, and myocardial structure and function were assessed by echocardiography. Cardiomyocytes were isolated by Langendorff perfusion and subjected to iTRAQ-based quantitative membrane proteomic profiling, immunoblotting, and real-time quantitative reverse-transcriptase polymerase chain reaction. Compared to controls, elderly T2DM mice showed worse systolic function, more myocardial fibrosis and up-regulation of several heart failure markers (all p < 0.05). Cardiomyocyte membrane proteomic profiling revealed that 417 proteins had differential expressions related to perturbations in several biological processes in T2DM mice compared with the control. The most up-regulated proteins were involved in oxidative phosphorylation, whereas many down-regulated proteins were involved in cytoskeletal regulation. Differential protein expression correlated with myocardial systolic velocity by tissue Doppler. In addition, cardiomyocyte immunofluorescence staining showed greater disorganization of thick/parallel F-actin stress fibers and marked reduction in F-to-G-actin ratio in T2DM vs control (p < 0.05), which paralleled worsened myocardial systolic velocity. We concluded that cardiac contractile dysfunction in elderly T2DM mice was associated with impaired energetics and cytoskeletal disorganization.
Reactivity and Chemoselectivity of Allenes in Rh(I)-Catalyzed Intermolecular (5 + 2) Cycloadditions with Vinylcyclopropanes: Allene-Mediated Rhodacycle Formation Can Poison Rh(I)-Catalyzed Cycloadditions (2014)

Allenes are important 2π building blocks in organic synthesis and engage as 2-carbon components in many metal-catalyzed reactions. Wender and co-workers discovered that methyl substituents on the terminal allene double bond counterintuitively change the reactivities of allenes in [Rh(CO)2Cl]2-catalyzed intermolecular (5 + 2) cycloadditions with vinylcyclopropanes (VCPs). More sterically encumbered allenes afford higher cycloadduct yields, and such effects are also observed in other Rh(I)-catalyzed intermolecular cycloadditions. Through density functional theory calculations (B3LYP and M06) and experiment, we explored this enigmatic reactivity and selectivity of allenes in [Rh(CO)2Cl]2-catalyzed intermolecular (5 + 2) cycloadditions with VCPs. The apparent low reactivity of terminally unsubstituted allenes is associated with a competing allene dimerization that irreversibly sequesters rhodium. With terminally substituted allenes, steric repulsion between the terminal substituents significantly increases the barrier of allene dimerization while the barrier of the (5 + 2) cycloaddition is not affected, and thus the cycloaddition prevails. Computation has also revealed the origin of chemoselectivity in (5 + 2) cycloadditions with allene-ynes. Although simple allene and acetylene have similar reaction barriers, intermolecular (5 + 2) cycloadditions of allene-ynes occur exclusively at the terminal allene double bond. The terminal double bond is more reactive due to the enhanced d-π* backdonation. At the same time, insertion of the internal double bond of an allene-yne has a higher barrier as it would break π conjugation. Substituted alkynes are more difficult to insert compared with acetylene, because of the steric repulsion from the additional substituents. This leads to the greater reactivity of the allene double bond relative to the alkynyl group in allene-ynes.
Coherent decorrelating detector with imperfect channel estimates for CDMA Rayleigh fading channels (2002)

A coherent multiuser decorrelating detector for an asynchronous CDMA, time-varying Rayleigh fading channel is proposed and analyzed. The detector employs fractionally sampled correlators' outputs at time instants corresponding to users' relative delays to simultaneously achieve two goals: the novel realization of a one-shot decorrelator with lower computational complexity; and to exploit a form of the time diversity for improved error performance compared to symbol spaced sampling. The decision statistics are formed from the decorrelator output according to the maximal ratio combining rule. The proposed detector performance is compared to that of a conventional symbol-spaced receiver in a single-user environment, and the impact of the channel estimation error is illustrated.
Continuous Electrical Tuning of the Chemical Composition of TaO x -Based (2012)

TaOx-based memristors have recently demonstrated both sub- nanosecond resistance switching speeds and very high write/erase switching en- durance. Here we show that the physical state variable that enables these prop- erties is the oxygen concentration in a conduction channel, based on the measurement of the thermal coeffi- cient of resistance of different TaOx memristor states and a set of reference TaO films of known composition. The continuous electrical tunability of the oxygen concentration in the channel, with a resolution of a few percent, was demonstrated by controlling the write currents with a one transistor-one memristor (1T1M) circuit. This study demonstrates that solid-state chemical kinetics is important for the determination of the electrical characteristics of this relatively new class of device.
Decreased susceptibility of Candida albicans to azole antifungals: a complication of long-term treatment in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) patients (2007)

Multiple courses (>6) of fluconazole annually and low dose prophylaxis are major risk factors for persistent colonization with C. albicans with decreased susceptibility in APECED patients.
Quality and parameter control of X-ray absorption gratings by angular X-ray transmission (2019)

Here we report on a non-destructive, spatially resolving and easy to implement quality and parameter control method for high aspect ratio X-ray absorption gratings. Based on angular X-ray transmission measurements, our proposed technique allows to determine the duty cycle, the transmittance, the height, as well as the local inclination of the absorbing grating structures. A key advantage of the presented method is a fast and extensive grating quality evaluation without the need of implementing an entire grating interferometer. In addition to the local and surface-based analysis using a scanning electron microscope, our non-destructive method provides global averaged macroscopic and spatially resolved grating structure information without the requirement of resolving individual grating lines.
Paclitaxel-coated balloon catheter versus paclitaxel-coated stent for the treatment of coronary in-stent restenosis: the three-year results of the PEPCAD II ISR study (2015)

The six-month superiority of the paclitaxel-coated balloon compared to the paclitaxel-eluting stent in the treatment of bare metal coronary in-stent restenosis persisted throughout the three-year clinical follow-up period indicating stability of the lesions treated. (ClinicalTrials.gov Identifier: NCT00393315).
Globin genes: a paradigm of gene structure, function, and evolution. (1982)

Access to the detailed structure of the globin (and other) genes has taught us at least three valuable, but not necessarily expected, lessons regarding the structure and evolution of the genes. Foremost, at least in terms of its surprising nature, is the fact that many genes are interrupted, i.e., they contain discontinuous blocks of coding and noncoding information. No less surprising are the accompanying facts that chromosomal DNA changes by the movement and rearrangement of large pieces of DNA and that genetic loci are highly and unexpectedly complex, consisting of arrays of related genes and pseudo (or apparently nonfunctional) genes. Here we review some of the evidence upon which these conclusions rest, and we try to form a coherent picture of gene evolution. The evidence that we shall use is based on studies of the mouse globin. Evidence from various other genetic systems leads us to believe that these genes serve as an instructive general model rather than an idiosyncratic one.
All-Scale Hierarchically Structured p-Type PbSe Alloys with High Thermoelectric Performance Enabled by Improved Band Degeneracy (2019)

We show an example of hierarchically designing electronic bands of PbSe toward excellent thermoelectric performance. We find that alloying 15 mol % PbTe into PbSe causes a negligible change in the light and heavy valence band energy offsets (Δ E<sub>V</sub>) of PbSe around room temperature; however, with rising temperature it makes Δ E<sub>V</sub> decrease at a significantly higher rate than in PbSe. In other words, the temperature-induced valence band convergence of PbSe is accelerated by alloying with PbTe. On this basis, applying 3 mol % Cd substitution on the Pb sites of PbSe<sub>0.85</sub>Te<sub>0.15</sub> decreases Δ E<sub>V</sub> and enhances the Seebeck coefficient at all temperatures. Excess Cd precipitates out as CdSe<sub>1- y</sub>Te <sub>y</sub>, whose valence band aligns with that of the p-type Na-doped PbSe<sub>0.85</sub>Te<sub>0.15</sub> matrix. This enables facile charge transport across the matrix/precipitate interfaces and retains the high carrier mobilities. Meanwhile, compared to PbSe the lattice thermal conductivity of PbSe<sub>0.85</sub>Te<sub>0.15</sub> is significantly decreased to its amorphous limit of 0.5 W m<sup>-1</sup> K<sup>-1</sup>. Consequently, a highest peak ZT of 1.7 at 900 K and a record high average ZT of ∼1 (400-900 K) for a PbSe-based system are achieved in the composition Pb<sub>0.95</sub>Na<sub>0.02</sub>Cd<sub>0.03</sub>Se<sub>0.85</sub>Te<sub>0.15</sub>, which are ∼70% and ∼50% higher than those of Pb<sub>0.98</sub>Na<sub>0.02</sub>Se control sample, respectively.
METASTATIC PROGRESSION OF ENHANCING RENAL MASSES UNDER ACTIVE SURVEILLANCE IS ASSOCIATED WITH RAPID INTERVAL GROWTH OF THE PRIMARY TUMOR (2008)

You have accessJournal of Urology1 Apr 2008METASTATIC PROGRESSION OF ENHANCING RENAL MASSES UNDER ACTIVE SURVEILLANCE IS ASSOCIATED WITH RAPID INTERVAL GROWTH OF THE PRIMARY TUMOR David A Kunkle, David YT Chen, Richard E Greenberg, Rosalia Viterbo, and Robert G Uzzo David A KunkleDavid A Kunkle More articles by this author , David YT ChenDavid YT Chen More articles by this author , Richard E GreenbergRichard E Greenberg More articles by this author , Rosalia ViterboRosalia Viterbo More articles by this author , and Robert G UzzoRobert G Uzzo More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(08)61097-6AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "METASTATIC PROGRESSION OF ENHANCING RENAL MASSES UNDER ACTIVE SURVEILLANCE IS ASSOCIATED WITH RAPID INTERVAL GROWTH OF THE PRIMARY TUMOR." The Journal of Urology, 179(4S), p. 375 © 2008 by American Urological AssociationFiguresReferencesRelatedDetails Volume 179Issue 4SApril 2008Page: 375 Advertisement Copyright & Permissions© 2008 by American Urological AssociationMetricsAuthor Information David A Kunkle More articles by this author David YT Chen More articles by this author Richard E Greenberg More articles by this author Rosalia Viterbo More articles by this author Robert G Uzzo More articles by this author Expand All Advertisement PDF DownloadLoading ...
Industrial Agents: From the Holonic Paradigm to Industrial Cyber‐Physical Systems (2022)

This chapter introduces the main conceptual foundations of multi-agent systems and holonic systems and presents the framing of industrial agents as an instantiation of such technological paradigms to face industrial requirements such as, for example, those posed by industrial cyber-physical systems (ICPS). It addresses the alignment of industrial agents with RAMI 4.0. The chapter also addresses the use of industrial agents to realize ICPS, to concretely enhance the functionalities provided by the asset administration shells (AAS). Holonic paradigm translates the Köstler's observations and Herbert Simon's theories into a set of appropriate concepts for distributed control systems. Along with the holonics principles, an industrial agent usually has an associated physical hardware counterpart, which increases the deployment complexity. On the one side, the AAS is designed to be available for both non-intelligent and intelligent digitalized assets, which is also a digital basis for autonomous components and systems.
Neutrophil Conversion to a Tumor-Killing Phenotype Underpins Effective Microbial Therapy (2023)

Intratumoral injection of microbial bioparticles stimulates neutrophil antitumor functions, suggesting pathways for optimizing efficacy of microbial therapies and paving the way for their broader utilization in the clinic.
An Evolutionary Role for RNA-Mediated Epigenetic Variation? (2011)

This chapter explores RNA-mediated epigenetic variation, focusing on the role of small RNAs in the induction of gene expression during development. It discusses how epigenetic changes through RNA-mediated modification can induce and influence phenotypic changes in organisms.
Substituted 2-Hydroxy-1,2-dihydropyrrol-3-ones:  Fluorescent Markers Pertaining to Oxidative Stress and Aging (1996)

Previous observations that the aging process correlates with occurrence of certain fluorescent biological pigments have led to numerous efforts in elucidating the chemical nature of the fluorophores generated through reactions of primary amines and various products of lipid peroxidation. In this study, model reactions of saturated aldehydes with aliphatic amines in the presence of peroxides were found to generate structurally unusual fluorescent compounds. Substitution of a lysine-containing peptide for simpler amines has also yielded similar fluorescence. The spectral excitation and emission maxima (around 360 and 430 nm, respectively) of these fluorophores match those widely reported in peroxidized biological objects. The fluorescent compounds in our model studies have been chromatographically isolated and their structures determined through mass spectrometry, NMR spectrometry, and Fourier-transform infrared spectroscopy. The spectrometric data indicate the fluorescent products to be alkylated 2-hydroxy-1,2-dihydropyrrol-3-ones, obtained by the action of 1,2,4-triketone intermediates upon the primary amines. Independent syntheses of several 1,2,4-triketones were carried out. One such triketone reacted with hexylamine to form a fluorescent compound spectroscopically identical to the fluorescent reaction product of hexanal, hydrogen peroxide, and hexylamine.
Novel Amplitude FBG Sensor Made with fs-IR Radiation in SMF-28 Fiber for Multi-Parameter Bend Sensing (2007)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text D. Grobnic, S. J. Mihailov, R. B. Walker, and C. W. Smelser, "Novel Amplitude FBG Sensor Made with fs-IR Radiation in SMF-28 Fiber for Multi-Parameter Bend Sensing," in Bragg Gratings, Photosensitivity, and Poling in Glass Waveguides, OSA Technical Digest (CD) (Optica Publishing Group, 2007), paper JWA43. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Overcoming Intrinsic and Acquired Resistance Mechanisms Associated with the Cell Wall of Gram-Negative Bacteria (2020)

The global increase in multi-drug-resistant bacteria is severely impacting our ability to effectively treat common infections. For Gram-negative bacteria, their intrinsic and acquired resistance mechanisms are heightened by their unique cell wall structure. The cell wall, while being a target of some antibiotics, represents a barrier due to the inability of most antibacterial compounds to traverse and reach their intended target. This means that its composition and resulting mechanisms of resistance must be considered when developing new therapies. Here, we discuss potential antibiotic targets within the most well-characterised resistance mechanisms associated with the cell wall in Gram-negative bacteria, including the outer membrane structure, porins and efflux pumps. We also provide a timely update on the current progress of inhibitor development in these areas. Such compounds could represent new avenues for drug discovery as well as adjuvant therapy to help us overcome antibiotic resistance.