gebhart/patrepeval huggingface dataset:
X-Ku Wide-Bandwidth GaN HEMT MMIC Amplifier with Small Deviation of Output Power and PAE (2014)

A new design methodology was proposed to obtain wide-bandwidth and flat-group-delay reactive-matching GaN HEMT MMIC amplifiers. Frequency dependence of the optimal source and load impedance of a GaN HEMT are derived as polynomial equations and matching circuits are designed by small signal simulation without the use of large-signal transistor model and large-signal simulation. Fabricated GaN HEMT MMIC amplifiers, which show a small deviation of Pout and PAE in the range of 8-18 GHz, prove that our methodology is suitable for the design of a wide-bandwidth MMIC amplifier.
Effects of Increased Von Willebrand Factor Levels on Primary Hemostasis in Thrombocytopenic Patients with Liver Cirrhosis (2014)

In patients with liver cirrhosis procoagulant and anticoagulant changes occur simultaneously. During primary hemostasis, platelets adhere to subendothelial structures, via von Willebrand factor (vWF). We aimed to investigate the influence of vWF on primary hemostasis in patients with liver cirrhosis. Therefore we assessed in-vitro bleeding time as marker of primary hemostasis in cirrhotic patients, measuring the Platelet Function Analyzer (PFA-100) closure times with collagen and epinephrine (Col-Epi, upper limit of normal ≤ 165 s) or collagen and ADP (Col-ADP, upper limit of normal ≤ 118 s). If Col-Epi and Col-ADP were prolonged, the PFA-100 was considered to be pathological. Effects of vWF on primary hemostasis in thrombocytopenic patients were analyzed and plasma vWF levels were modified by adding recombinant vWF or anti-vWF antibody. Of the 72 included cirrhotic patients, 32 (44.4%) showed a pathological result for the PFA-100. They had mean closure times (± SD) of 180 ± 62 s with Col-Epi and 160 ± 70 s with Col-ADP. Multivariate analysis revealed that hematocrit (P = 0.027) and vWF-antigen levels (P = 0.010) are the predictors of a pathological PFA-100 test in cirrhotic patients. In 21.4% of cirrhotic patients with platelet count ≥ 150/nL and hematocrit ≥ 27.0%, pathological PFA-100 results were found. In thrombocytopenic (< 150/nL) patients with cirrhosis, normal PFA-100 results were associated with higher vWF-antigen levels (462.3 ± 235.9% vs. 338.7 ± 151.6%, P = 0.021). These results were confirmed by multivariate analysis in these patients as well as by adding recombinant vWF or polyclonal anti-vWF antibody that significantly shortened or prolonged closure times, respectively. In conclusion, primary hemostasis is impaired in cirrhotic patients. The effect of reduced platelet count in cirrhotic patients can at least be partly compensated by increased vWF levels. Recombinant vWF could be an alternative to platelet transfusions in the future.
Building-Blocks for Performance Oriented DSLs (2011)

Domain-specific languages raise the level of abstraction in software development. While it is evident that programmers can more easily reason about very high-level programs, the same holds for compilers only if the compiler has an accurate model of the application domain and the underlying target platform. Since mapping high-level, general-purpose languages to modern, heterogeneous hardware is becoming increasingly difficult, DSLs are an attractive way to capitalize on improved hardware performance, precisely by making the compiler reason on a higher level. Implementing efficient DSL compilers is a daunting task however, and support for building performance-oriented DSLs is urgently needed. To this end, we present the Delite Framework, an extensible toolkit that drastically simplifies building embedded DSLs and compiling DSL programs for execution on heterogeneous hardware. We discuss several building blocks in some detail and present experimental results for the OptiML machine-learning DSL implemented on top of Delite.
Extraction and restoration of hippocampal spatial memories with non-linear dynamical modeling (2014)

To build a cognitive prosthesis that can replace the memory function of the hippocampus, it is essential to model the input-output function of the damaged hippocampal region, so the prosthetic device can stimulate the downstream hippocampal region, e.g., CA1, with the output signal, e.g., CA1 spike trains, predicted from the ongoing input signal, e.g., CA3 spike trains, and the identified input-output function, e.g., CA3-CA1 model. In order for the downstream region to form appropriate long-term memories based on the restored output signal, furthermore, the output signal should contain sufficient information about the memories that the animal has formed. In this study, we verify this premise by applying regression and classification modelings of the spatio-temporal patterns of spike trains to the hippocampal CA3 and CA1 data recorded from rats performing a memory-dependent delayed non-match-to-sample (DNMS) task. The regression model is essentially the multiple-input, multiple-output (MIMO) non-linear dynamical model of spike train transformation. It predicts the output spike trains based on the input spike trains and thus restores the output signal. In addition, the classification model interprets the signal by relating the spatio-temporal patterns to the memory events. We have found that: (1) both hippocampal CA3 and CA1 spike trains contain sufficient information for predicting the locations of the sample responses (i.e., left and right memories) during the DNMS task; and more importantly (2) the CA1 spike trains predicted from the CA3 spike trains by the MIMO model also are sufficient for predicting the locations on a single-trial basis. These results show quantitatively that, with a moderate number of unitary recordings from the hippocampus, the MIMO non-linear dynamical model is able to extract and restore spatial memory information for the formation of long-term memories and thus can serve as the computational basis of the hippocampal memory prosthesis.
Durchblick bei Tag und Nacht (2013)

Abstract Rund um die Uhr bei jedem Wetter einsetzbare Aufklärungsmittel bieten für Wehrtechnik und Rettungsdienste entscheidende Einsatzvorteile. Gegenüber anderen Technologien zeigen SWIR (short wave infrared light)‐Kameras durchgängig gute Resultate, die sie für den praktischen Einsatz empfehlen. Für die gleichzeitige Erkennung und Verfolgung sowohl thermisch strahlender als auch reflektierender Objekte lassen sich SWIR‐ und thermische LWIR (long wave infrared)‐Kameras leicht kombinieren.
Molecular Dynamics Simulation of Equine Infectious Anemia Virus Tat Protein in Water and in 40% Trifluoroethanol (1994)

Abstract Two molecular dynamics (MD) simulations were performed in order to increase the understanding of the dependence of protein conformation on solvent environment. The protein used for these simulations is the transcriptional activator of the equine infectious anemia virus (EIAV-Tat). The structure of this protein has been determined by nuclear magnetic resonance (NMR) in aqueous solution (Willbold et al., Science 264, 1584 (1994)) and in 40% (v/v) trifluoroethanol (TFE) (Sticht et al., Eur. J. Biochem., submitted) showing considerable differences in the stability of the secondary structure elements. In order to investigate the influence of the solvent MD simulations (300 K; 200 ps) were carried out in water and in a solvent containing 40% (v/v) TFE. In both simulations the structure as determined in 40% TFE by NMR, showing three-helices and a tight type II turn, was used as the initial structure. The MD simulations clearly indicate a decreased stability of the secondary structure elements in aqueous environment as made obvious by larger atomic motions and stronger fluctuations in the length of the hydrogen bonds. Complete unfolding of the helices was not observed on a 200 ps timescale. The root mean square deviation (RMSD) values of the backbone atoms after 200 ps simulation compared to the starting structure underline the strong influence of the solvent on the protein stability. This RMSD value is 1.95 Å for the simulation in water and 1.29 Å for the simulation in TFE/water. This result supports the notion that TFE acts as a secondary structure inducing and stabilizing solvent. The differences apparent from the MD simulations are in good agreement with the data derived from NMR measurements, showing the relevance of MD as a method for estimating conformational and dynamical properties of proteins.
ChemInform Abstract: Chiral (Salen)Mn(III) Complexes in Asymmetric Epoxidations: Practical Synthesis of cis‐Aminoindanol and Its Applications to Enantiopure Drug Synthesis (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Design of a Passive Ranging System Using Existing Distance Measuring Equipment (DME) Signals & Transmitters (2015)

The US Federal Aviation Administration (FAA) is developing alternative navigation concepts to maintain operational capacity and efficiency even with the loss of Global Positioning System (GPS). One concept being studied for alternative position navigation and timing (APNT) is a ground based passive ranging system. This system has few capacity constraints and can provide other benefits. The APNT passive ranging system would use existing FAA terrestrial infrastructure, particularly distance measuring equipment (DME) ground beacons. APNT project team has developed a DME Pseudolite (PL) concept that enables a passive ranging signal on DME that is compatible with existing DME operations. It can provide additional benefits for APNT and non-APNT users with its data transmission. This paper introduces the DME PL concept and assesses the potential performance of the system. The paper focuses on signal structure design for best data capacity. It formulates a methodology and modeling for the developing the design. Copyright © 2015 Institute of Navigation.
Abstract P36 (2015)

AMERICAN SOCIETY OF PLASTIC SURGEONS PLASTIC & RECONSTRUCTIVE SURGERY PRS GLOBAL OPEN ASPS EDUCATION NETWORK AMERICAN SOCIETY OF PLASTIC SURGEONS PLASTIC & RECONSTRUCTIVE SURGERY PRS GLOBAL OPEN ASPS EDUCATION NETWORK
An Unusual Fullerene–Carbene Adduct: Thermal Motion, Disorder, or Both?** (2023)

Abstract A single‐crystal X‐ray study of a fullerene‐imidazole adduct at nine temperatures (80 K≤ T ≤480 K), accompanied by energy calculations, strongly suggested thermal motion of the C 60 moiety with respect to the imidazolium heterocycle. Analysis of the anisotropic displacement parameters, calculations of frequencies, and the refinement of disorder models for the crystal at four temperatures (230 K≤ T ≤380 K) lead to the conclusion that the rotator is moving at all temperatures. The rotation barrier is low, with one preferred crystallographic site and several other energy minima.
Detecting Aggregate Bursts from Scaled Bins within the Context of Privacy (2007)

In this paper, we consider burst detection within the context of privacy. In our scenario, multiple parties want to detect a burst in aggregated time series data, but none of the parties want to disclose their individual data. We introduce two data perturbation approaches that alter the local data so that raw time series data values are not shared and bursts can be identified using a Shewhart threshold. The first involves lossy data compression via windowing. Unfortunately, windowing alone does not guarantee enough privacy because the envelope of the time series can still be determined. Therefore, we introduce a second data perturbation approach that employs scaled binning. This method transmits values for each data point based on the distance of the data point to a local mean of the time series. The strength of this approach is its increased privacy. We empirically demonstrate the burst detection results using both real and synthetic distributed data sets. When attempting to optimize both privacy guarantees and burst detection accuracy, we find that a combined approach using both windowing and scaled binning balances burst accuracy and privacy better than either approach individually.
Predicción molecular de serotipos de Streptococcus suis aislados de granjas porcinas en México (2021)

Infections caused by Streptococcus suis (S. suis) pose a problem for the pig industry worldwide. Pigs often carry multiple serotypes of S. suis in the upper respiratory tract, where S. suis is frequently isolated from. The clinical diagnosis of the infection is presumptive and is generally based on clinical signs, the age of the animal and macroscopic lesions. In the laboratory, identification of S. suis is performed biochemically, and then, serotyping is performed with antisera to determine the serotype, but these tests can be inconclusive. To date, there are few studies that have documented the presence and diversity of S. suis serotypes in Mexico. In the present study, it was characterized S. suis strains from Mexican pig farms using molecular approaches; samples were first processed by PCR of the gdh gene to detect S. suis. Positive samples were then subjected to a two-step multiplex PCR (cps PCR) to detect and characterize each strain; the first step consisted of a grouping PCR and the second step consisted of a typing PCR. The serotypes detected in the pig farming areas of Mexico included 1/2, 2, 3, 5, 7, 8, 9, 17, and 23. These findings are important for the characterization of serotypes present in Mexico and for outbreak prevention.
Immunohistochemical staining of an arthritic knee joint injected with low molecular weight urokinase plasminogen activator (2011)

<b>Copyright information:</b>Taken from "Urokinase, a constitutive component of the inflamed synovial fluid, induces arthritis"Arthritis Research &amp; Therapy 2002;5(1):R9-R17.Published online 17 Oct 2002PMCID:PMC154426.Copyright © 2003 Jin et al., licensee BioMed Central Ltd. This is an Open Access article: Media for any non-commercial purpose, provided this notice is presented along with the articles original URL. Abundance of mononuclear cells expressing Mac-1 (red–brown colour) in the inflamed synovial tissue. Original magnification × 20. Arthritic knee joint stained with irrelevant goat IgG. JC, joint cavity; C, cartilage; ST, synovial tissue.
DESIGN OF HIGH VOLTAGE 4H-SiC SUPERJUNCTION SCHOTTKY RECTIFIERS (2004)

This paper presents a novel Schottky rectifier structure based on the superjunction approach, which is utilizes 2- and 3-D field shaping to increase the avalanche breakdown voltage. Device forward and blocking characteristics are analyzed with numerical simulations and compared with conventional 4 H - SiC Schottky rectifiers. Optimal design tradeoffs between breakdown voltage and specific on-resistance are obtained for high voltage 4 H - SiC superjunction Schottky rectifiers. The results show that the new structure can provide a 20 × lower R on,sp than conventional Schottky rectifier for 6kV device. In addition, device termination and possible fabrication steps for the superjunction devices are also presented.
Demo: Implementing advanced network functions with stateful programmable data planes (2017)

Stateful programmable dataplanes are emerging as a disruptive technology and an enabler factor for network function virtualization in SDN environments. In this demo paper we show three real world use cases with stateful forwarding requirements to validate both the hardware and software implementations of the Open Packet Processor data plane.
Toxic Shock Syndrome Toxin 1 Resistance in Mice is Related to Interleukin 1 Production by Toxic Shock Syndrome Toxin 1 (1989)

Toxic Shock Syndrome Toxin 1 Resistance in Mice is Related to Interleukin 1 Production by Toxic Shock Syndrome Toxin 1 Get access T. Ikejima, T. Ikejima Tufts University School of Medicine and New England Medical Center Hospitals, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar S. F. Orencole, S. F. Orencole Tufts University School of Medicine and New England Medical Center Hospitals, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar S. J. C. Warner, S. J. C. Warner Tufts University School of Medicine and New England Medical Center Hospitals, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar C. A. Dinarello C. A. Dinarello Tufts University School of Medicine and New England Medical Center Hospitals, Boston, Massachusetts Search for other works by this author on: Oxford Academic PubMed Google Scholar Reviews of Infectious Diseases, Volume 11, Issue Supplement_1, January-February 1989, Page S329, https://doi.org/10.1093/clinids/11.Supplement_1.S330 Published: 01 January 1989
Quantitative identification of magnetic resonance imaging features of prostate cancer response following laser ablation and radical prostatectomy (2014)

Laser interstitial thermotherapy (LITT) is a relatively new focal therapy technique for the ablation of localized prostate cancer. In this study, for the first time, we are integrating ex vivo pathology and magnetic resonance imaging (MRI) to assess the imaging characteristics of prostate cancer and treatment changes following LITT. Via a unique clinical trial, which gave us the availability of ex vivo histology and pre- and post-LITT MRIs, (1) we investigated the imaging characteristics of treatment effects and residual disease, and (2) evaluated treatment-induced feature changes in the ablated area relative to the residual disease. First, a pathologist annotated the ablated area and the residual disease on the ex vivo histology. Subsequently, we transferred the annotations to the post-LITT MRI using a semi-automatic elastic registration. The pre- and post-LITT MRIs were registered and features were extracted. A scoring metric based on the change in median pre- and post-LITT feature values was introduced, which allowed us to identify the most treatment responsive features. Our results show that (1) image characteristics for treatment effects and residual disease are different, and (2) the change of feature values between pre- and post-LITT MRIs can be a quantitative biomarker for treatment response. Finally, using feature change improved discrimination between the residual disease and treatment effects.
Incisional Hernia Following Hand-Assisted Laparoscopic Surgery for Renal Cell Cancer (2005)

No AccessJournal of UrologyUrological Survey: Urolithiasis, Endourology and Laparoscopy1 Dec 2005Incisional Hernia Following Hand-Assisted Laparoscopic Surgery for Renal Cell Cancer Ralph V. ClaymanM.D. Ralph V. ClaymanRalph V. Clayman More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)68934-1AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Incisional Hernia Following Hand-Assisted Laparoscopic Surgery for Renal Cell Cancer." The Journal of Urology, 174(6), pp. 2148–2149 © 2005 by American Urological Association, Inc.FiguresReferencesRelatedDetails Volume 174Issue 6December 2005Page: 2148-2149 Advertisement Copyright & Permissions© 2005 by American Urological Association, Inc.MetricsAuthor Information Ralph V. Clayman More articles by this author Expand All Advertisement PDF DownloadLoading ...
CD4 T-Lymphocyte Activation in Asthma Is Accompanied by Increased Serum Concentrations of Interleukin-5: Effect of Glucocorticoid Therapy (1993)

Peripheral blood mononuclear cells (PBMC) and serum were obtained, on two occasions, from 15 asthmatic patients who required oral glucocorticoid therapy for moderate to severe disease exacerbations. Samples were obtained immediately before commencement of oral glucocorticoids (Day 1) and again after 7 days of treatment (Day 7), when lung function had significantly improved. Samples were also isolated on two occasions 7 days apart from a group of seven untreated volunteers. Expression of CD25, human lymphocyte antigen (HLA-)DR, CD45RA, and CD45RO on CD4 and CD8 T lymphocytes was measured by flow cytometry, and serum concentrations of interleukin-5 (IL-5) were measured using an enzyme-linked immunosorbent assay technique. On Day 1 the asthmatic patients showed significantly higher percentages, as compared with the control subjects of CD4 T lymphocytes expressing the markers CD25, HLA-DR, and CD45RO and significantly lower percentages of CD4 T cells expressing CD45RA. After glucocorticoid therapy, the percentages of CD4 T cells expressing CD25, HLA-DR, and CD45RO were significantly reduced in the asthmatic patients, and the percentages of those expressing CD45RA significantly increased so that by Day 7 expression of all four markers was no longer significantly different from that of the control subjects. By contrast, the percentages of CD8 T cells expressing HLA-DR, CD45RA, and CD45RO in the PBMC of the asthmatic patients on Day 1 were not significantly different from those in control subjects, whereas the percentages of CD25 expressing CD8 T cells were only marginally elevated. Glucocorticoid therapy resulted in no significant change in the expression of all four markers on CD T cells.(ABSTRACT TRUNCATED AT 250 WORDS)
An Eco‐friendly Soft Template Synthesis of Mesostructured Silica‐Carbon Nanocomposites for Acid Catalysis (2015)

Abstract The synthesis of ordered mesoporous silica‐carbon composites was explored by employing TEOS and sucrose as the silica and carbon precursor respectively, and the triblock copolymer F127 as a structure‐directing agent via an evaporation‐induced self‐assembly (EISA) process. It is demonstrated that the synthesis procedures allow for control of the textural properties and final composition of these silica‐carbon nanocomposites via adjustment of the effective SiO 2 /C weight ratio. Characterization by SAXS, N 2 physisorption, HRTEM, TGA, and 13 C and 29 Si solid‐state MAS NMR show a 2D hexagonal mesostructure with uniform large pore size ranging from 5.2 to 7.6 nm, comprising of separate carbon phases in a continuous silica phase. Ordered mesoporous silica and non‐ordered porous carbon can be obtained by combustion of the pyrolyzed nanocomposites in air or etching with HF solution, respectively. Sulfonic acid groups can be readily introduced to such kind of silica‐carbon nanocomposites by a standard sulfonation procedure with concentrated sulfuric acid. Excellent acid‐catalytic activities and selectivities for the dimerization of styrene to produce 1,3‐diphenyl‐1‐butene and dimerization of α‐methylstyrene to unsaturated dimers were demonstrated with the sulfonated materials.
Oils of nature. (2008)

The increasing consumption of planet resources and the environmental damages induced by chemical synthesis are today’s hot problems. Therefore, all western countries are now sensitized to the importance of using renewable resources as cosmetic ingredients as much as possible. Indeed, a modern approach to new ‘green’ cosmetics consists in the scientific study and rational investigation of renewable ingredients, many of them still little known.
Colorless Optical Network Unit Based on Silicon Photonic Components for WDM PON (2012)

We demonstrate a low-cost colorless optical network unit (ONU) utilizing silicon photonic components for wavelength division multiplexed passive-optical-networks. At the ONU, a waveguide-coupled microring works as a demultiplexer for separating the downstream signal from the centrally distributed continuous-wave (CW) light. The 10-Gb/s downstream signal is received using a waveguide-integrated germanium photodetector while the CW light is further modulated at 5 Gb/s using a silicon microring modulator for upstream signal generation. Error-free transmission over 25-km single mode fiber is achieved with 0.2- and 0.4-dB power penalties for the downstream and upstream signals, respectively. Complementary metal-oxide semiconductor-compatible silicon photonic technology offers the potential for monolithic integration and mass production.