gebhart/patrepeval huggingface dataset:
CORFU: a shared log design for flash clusters (2012)

CORFU 1 organizes a cluster of flash devices as a single, shared log that can be accessed concurrently by multiple clients over the network. The CORFU shared log makes it easy to build distributed applications that require strong consistency at high speeds, such as databases, transactional key-value stores, replicated state machines, and metadata services. CORFU can be viewed as a distributed SSD, providing advantages over conventional SSDs such as distributed wear-leveling, network locality, fault tolerance, incremental scalability and geodistribution. A single CORFU instance can support up to 200K appends/sec, while reads scale linearly with cluster size. Importantly, CORFU is designed to work directly over network-attached flash devices, slashing cost, power consumption and latency by eliminating storage servers. 1
A fast model for distributed scattering from buildings (2009)

Recent studies highlighted the important role of diffuse (or distributed) scattering in determining the actual time- and angle-dispersion of the radio channel in urban environment. Diffused scattering however, is inherently a “distributed” phenomenon, i.e. it takes origin from every single surface spot, and therefore its prediction requires a great deal of computational resources. In the present paper a novel formulation is presented which allows the fast computation of the power-angle profile related to distributed scattering from a single wall adopting simple analytical formulas.
Ion-Exchangeable Functional Binders and Separator for High Temperature Performance of Li1.1Mn1.86Mg0.04O4Spinel Electrodes in Lithium Ion Batteries (2013)

Since LiMn2O4 spinel materials are inexpensive, environmentally-friendly, and safe, they are considered a promising cathode candidate for lithium ion batteries in EVs to replace commercialized materials such as LiCoO2, LiNi1/3Mn1/3Co1/3O2 and LiNi0.5Co0.2Mn0.3O2. However, LiMn2O4 spinel electrodes severely degrade at high temperature due to Mn dissolution. Also, the dissolved Mn2+ ions causes self-discharge where reduction of Mn2+ ions into Mn metals occurs on a graphite anode surface accompanied by oxidation of lithiated graphite at a charged state, and this results in severe capacity fading at high temperature. In this study, ion-exchangeable binders and a separator having functional groups of sodium carboxylate or sulfonate are, for the first time, examined to solve the Mn dissolution problem of LiMn2O4 spinel materials at high temperature. Ion exchange between Na+ ions of the functional groups of the binders and the separator and dissolved Mn2+ ions of the LiMn2O4 electrodes inhibits self-discharge, resulting in improved cycle performance. This result is supported by the IR spectra of the binders, an ICP analysis of the electrolytes, and ex situ XRD patterns of lithiated graphite electrodes.
Seneca: Remote Mirroring Done Write (2003)

Remote mirroring is widely deployed, but its complexities are surprisingly poorly understood. This means that data is less well protected than it ought to be, and possible optimizations are infrequently taken advantage of. To address these difficulties, we (1) demystify the design space by presenting a taxonomy of the approaches in use, (2) describe Seneca – a new asynchronous remote-mirroring protocol that supports write coalescing, asynchronous propagation, and in-order delivery, and (3) report on a performance and correctness validation of Seneca. We are confident that the result is a robust remote-mirroring protocol that provides good performance and predictable behavior in the face of a wide range of failure types, such as rolling disasters. 1
Foundational Issues in Touch-Surface Stroke Gesture Design (2012)

The advent of modern touchscreen devices has unleashed many opportunities and calls for innovative use of stroke gestures as a richer interaction medium. A significant body of knowledge on stroke gesture design is scattered throughout the Human-Computer Interaction research literature. Primarily based on the authors' own decade-long gesture user interface (UI) research which launched the word-gesture keyboard paradigm, Foundational Issues in Touch- Surface Stroke Gesture Design - An Integrative Review synthesizes some of the foundational issues of human motor control complexity, visual and auditory feedback, and memory and learning capacity concerning gesture user interfaces. In the second half of the survey a set of gesture UI design principles is derived from the research literature. The survey also covers system implementation aspects of gesture UI such as gesture recognition algorithms and design toolkits. Foundational Issues in Touch-Surface Stroke Gesture Design - An Integrative Review is an ideal primer for researchers and graduate students embarking on research in gesture interfaces. It is also an excellent reference for designers and developers who want to leverage insights and lessons learned in the academic research community.
Deletion of accessory genes 3a, 3b, 5a or 5b from avian coronavirus infectious bronchitis virus induces an attenuated phenotype both in vitro and in vivo (2018)

Avian coronavirus infectious bronchitis virus (IBV) infects domestic fowl, resulting in respiratory disease and causing serious losses in unprotected birds. Its control is mainly achieved by using live attenuated vaccines. Here we explored the possibilities for rationally attenuating IBV to improve our knowledge regarding the function of IBV accessory proteins and for the development of next-generation vaccines with the recently established reverse genetic system for IBV H52 based on targeted RNA recombination and selection of recombinant viruses in embryonated eggs. To this aim, we selectively removed accessory genes 3a, 3b, 5a and 5b individually, and rescued the resulting recombinant (r) rIBV-Δ3a, rIBV-Δ3b, rIBV-Δ5a and rIBV-Δ5b. In vitro inoculation of chicken embryo kidney cells with recombinant and wild-type viruses demonstrated that the accessory protein 5b is involved in the delayed activation of the interferon response of the host after IBV infection. Embryo mortality after the inoculation of 8-day-old embryonated chicken eggs with recombinant and wild-type viruses showed that rIBV-Δ3b, rIBV-Δ5a and rIBV-Δ5b had an attenuated phenotype in ovo, with reduced titres at 6 h p.i. and 12 h p.i. for all viruses, while growing to the same titre as wild-type rIBV at 48 h p.i. When administered to 1-day-old chickens, rIBV-Δ3a, rIBV-Δ3b, rIBV-Δ5a and rIBV-Δ5b showed reduced ciliostasis in comparison to the wild-type viruses. In conclusion, individual deletion of accessory genes in IBV H52 resulted in mutant viruses with an attenuated phenotype.
Supplementary Materials and Methods from Characterization of an Oxaliplatin Sensitivity Predictor in a Preclinical Murine Model of Colorectal Cancer (2023)

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Synthesis and Optical Properties of Photochromic Perinaphthothioindigo (2005)

(1,2-naphtho)(1,8-naphtho)thioindigo (PNT) has been synthesized following a simple Friedel-Crafts route and its photochemical properties in toluene and PMMA characterized. PNT is a photochromic molecule capable of reversible photoisomerization between a yellow form (cis-PNT, {lambda}{sub max} = 484 nm) and a purple form (trans-PNT, {lambda}{sub max} = 595 nm). The stable purple form converts to the yellow form with a trans-PNT to cis-PNT conversion quantum yield of 0.027 in toluene and 0.062 in PMMA. The unstable yellow form exhibits a cis-PNT to trans-PNT quantum efficiency of conversion of 0.27-0.85 in toluene and 0.17-0.68 PMMA, with highest conversion efficiency occurring in the vicinity of its {lambda}{sub max} of 484 nm. Trans-PNT has a strong fluorescence quantum yield, 0.14 (toluene) and 0.16 (PMMA). For samples prepared photochemically in the cis-PNT form, slow thermal relaxation to the trans form occurs in the dark, with a half life of about 17 hours in toluene (25 C) and even slower, 168 hours, in PMMA. The property of photoswitching between fluorescent and non-fluorescent forms makes this material a candidate for many applications in imaging and data storage. An anomalous excitation profile for the fluorescence from trans-PNT, showing a dip at {approx}600 nm, is an agreement with the wavelength-dependent quantum yield of conversion from trans-PNT to cis-PNT, which is highest at the absorbance peak.
Biomechanical Evaluation of the CD HORIZON Spire Z Spinal System With Pedicle and Facet Fixation (2016)

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Antibody-Mediated Protection against Infection withHelicobacter pyloriin a Suckling Mouse Model of Passive Immunity (2009)

Studies of active immunization against Helicobacter pylori indicate that antibodies play a minor role in immunity. There is also evidence, however, that the translocation of antibodies in the stomach may be insufficient to achieve functional antibody levels in the gastric lumen. We have used a suckling mouse model of passive immunity to determine if perorally delivered antibodies can protect against infection with H. pylori. Female C57BL/6 mice were immunized parenterally with formalin-fixed cells of three clinical isolates of H. pylori (3HP) or the mouse-adapted H. pylori strain SS1 before mating. Their pups were challenged with the SS1 strain at 4 days of age and left to suckle before determination of bacterial loads 14 days later. Compared to age-matched controls, pups suckled by 3HP-vaccinated dams were significantly protected against infection (>95% reduction in median bacterial load; P<0.0001). Pups suckled by SS1-vaccinated dams were also significantly protected in terms of both median bacterial load (>99.5% reduction; P<0.0001) and the number of culture-negative pups (28% versus 2% for immune and nonimmune cohorts, respectively; P<0.0001). Similar results were obtained with pups suckled by dams immunized with a urease-deficient mutant of SS1. Fostering experiments demonstrated that protection was entirely attributable to suckling from an immunized dam, and antibody isotype analysis suggested that protection was mediated by the immunoglobulin G fraction of immune milk. Analysis of the bacterial loads in pups sampled before and after weaning confirmed that infection had been prevented in culture-negative animals. These data indicate that antibodies can prevent colonization by H. pylori and suppress the bacterial loads in animals that are colonized.
Successful Dynamic Closure Test Using Controlled Flow Back in the Vaca Muerta Formation (2016)

Abstract The Vaca Muerta formation is a shale oil and gas reservoir under active tectonics created by the Andes which are compressing the basin in an east to west direction and creates a varying stress regime both in horizontal and vertical directions. Additionally, this formation is composed of alternating layers of three litho-types with contrasted mechanical properties. These are organic shale, carbonate and ash beds. Slippage or debonding at weak-strong interfaces separating laminations is suspected to further contribute to the development of horizontal fracture components or T-Shape fractures during hydraulic fracturing when the fracturing pressure reaches the overburden (Zhang et al. 2007). Selecting the proper landing position of horizontal wells in these compressive environments depends not only on the reservoir quality but also in selecting a layer which combines lower stress with sufficient vertical connectivity, thus minimizing detrimental effect from T-Shape propagation behavior. Closure pressure can be obtained by performing a Dynamic in Situ Stress Test by force-closing the fracture (Nolte 1979; Raaen and Brudy, 2001). To this effect, YPF initiated in 2015 a campaign of in situ stress measurements across the Quintuco-Vaca Muerta system in vertical exploration and pilot wells. The objective was not only to predict a more accurate mud weight window to drill through the Vaca Muerta but mostly to measure as best as possible the difference between the overburden and the minimum horizontal stress to build a mechanical earth model accurate enough to help select better landing points for horizontal wells. There are 3 scales at which dynamic closure tests are performed. At the smallest scale, a micro-fracture is created by pumping a little amount of drilling fluid at few liters/minute in 1m open hole isolated between straddle packers. At the largest scale, in a cased-hole perforated well, the dynamic closure test is performed as part of fracturing data acquisition before fracture operation: at this scale the test involves tens of bbls pumped at 5-10 bpm. Finally stress can be measured during Extended Leakoff Test (ELOT or XLOT) acquired in open hole at the casing shoe. After a literature review of the development of the flow back method this paper presents extensive details and operational procedure recommendations that were obtained from successful XLOT combining multiple cycles with injection, forced flow back and reopening sequence in the Neuquén basin.
Generative Visual Dialogue System via Weighted Likelihood Estimation (2019)

The key challenge of generative Visual Dialogue (VD) systems is to respond to human queries with informative answers in natural and contiguous conversation flow. Traditional Maximum Likelihood Estimation-based methods only learn from positive responses but ignore the negative responses, and consequently tend to yield safe or generic responses. To address this issue, we propose a novel training scheme in conjunction with weighted likelihood estimation method. Furthermore, an adaptive multi-modal reasoning module is designed, to accommodate various dialogue scenarios automatically and select relevant information accordingly. The experimental results on the VisDial benchmark demonstrate the superiority of our proposed algorithm over other state-of-the-art approaches, with an improvement of 5.81% on recall@10.
Multi-resonance UWB Antenna with Improved Band Notch Characteristics (2005)

A UWB dipole antenna with flat and sharp band notch characteristics is proposed to obtain both WLAN band notch and a compact UWB RF-front structure. To achieve all these characteristics, the antenna acts as a multi-resonance radiator. To suppress interference from the WLAN system, the antenna is sharply mismatched at the WLAN band. To guarantee suppression in the band, the notch characteristics are flat in the WLAN band. The fabricated antenna has an operating bandwidth of 2.7 GHz to 11.0 GHz for VSWR <2. The rejected frequency range is measured as 5.10 GHz to 5.75 GHz for -3 dB return loss. The radiated power at this band is measured as 15 dB less than the power at the operating frequency band. From the measured results, it is apparent that the proposed antenna provides a compact RF-front in the UWB system without an additional circuit for the suppression of the WLAN band.
On Hair Color in France (2004)

Sex-linked coloration is a familiar phenomenon in the animal kingdom. Most people are familiar with the bright coloration of the male in many species of birds [2]. Instances of sex-linking of hair color in mammals are rare, but not unknown. For example, the tricolor pattern in the domestic house cat felix domesticus is found almost exclusively in the female [4]. We report here our discovery of sex-linking of hair coloration in a population of humans (homo sapiens). It is, to our knowledge, the first such reported observation in this species.
Receptor-DNA interactions: EMSA and footprinting (2009)

Defining the precise promoter DNA sequence motifs where nuclear receptors and other transcription factors bind is an essential prerequisite for understanding how these proteins modulate the expression of their specific target genes. The purpose of this chapter is to provide the reader with a detailed guide with respect to the materials and the key methods required to perform this type of DNA-binding analysis. Irrespective of whether starting with purified DNA-binding proteins or somewhat crude cellular extracts, the tried-and-true procedures described here will enable one to accurately access the capacity of specific proteins to bind to DNA as well as to determine the exact sequences and DNA contact nucleotides involved. For illustrative purposes, we primarily have used the interaction of the androgen receptor with the rat probasin proximal promoter as our model system.
Reverberation time estimation on the ACE corpus using the SDD method. (2015)

Reverberation Time (T60) is an important measure for characterizing the properties of a room. The author's T60 estimation algorithm was previously tested on simulated data where the noise is artificially added to the speech after convolution with a impulse responses simulated using the image method. We test the algorithm on speech convolved with real recorded impulse responses and noise from the same rooms from the Acoustic Characterization of Environments (ACE) corpus and achieve results comparable results to those using simulated data.
Chronic low back pain, bacterial infection and treatment with antibiotics (2021)

The contribution of bacterial infection to chronic low back pain and its treatment with antibiotics have generated considerable controversy in literature. If efficacious, antibiotics have the potential to transform the treatment of chronic low back pain in a significant subset of patients. Some microbiology studies of disc tissue from patients with CLBP have shown that bacteria are present, most likely due to infection, while others conclude they are absent or if found, it is due to surgical contamination. Clinical studies testing the efficacy of oral antibiotics to treat CLBP have either shown that the treatment is efficacious leading to significantly reduced pain and disability or that their effect is modest and not clinically significant. Critical review of the literature on CLBP, bacterial infection and treatment with antibiotics identified five well-designed and executed microbiology studies characterizing bacteria in disc samples that demonstrate that bacteria do infect herniated disc tissue, but that the bacterial burden is low and may be below the limits of detection in some studies. Two randomized, controlled clinical trials evaluating oral antibiotics in patients with CLBP indicate that for certain subsets of patients, the reduction in pain and disability achieved with antibiotic therapy may be significant. In patients for whom other therapies have failed, and who might otherwise progress to disc replacement or fusion surgery, antibiotic therapy may well be an attractive option to reduce the individual suffering associated with this debilitating condition. Additional clinical research is recommended to refine the selection of patients with CLBP caused or complicated by bacterial infection and most likely to respond to antibiotics, to optimize antibiotic therapy to maximize patient benefit, to minimize and manage side effects, and to address legitimate concerns about antibiotic stewardship.
Enantioselective Synthesis of Homoallylic Amines through Reactions of (Pinacolato)allylborons with Aryl-, Heteroaryl-, Alkyl-, or Alkene-Substituted Aldimines Catalyzed by Chiral C1-Symmetric NHC−Cu Complexes (2011)

A catalytic method for enantioselective synthesis of homoallylamides through Cu-catalyzed reactions of stable and easily accessible (pinacolato)allylborons with aryl-, heteroaryl-, alkyl-, or alkenyl-substituted N-phosphinoylimines is disclosed. Transformations are promoted by 1-5 mol % of readily accessible NHC-Cu complexes, derived from C(1)-symmetric imidazolinium salts, which can be prepared in multigram quantities in four steps from commercially available materials. Allyl additions deliver the desired products in up to quantitative yield and 98.5:1.5 enantiomeric ratio and are amenable to gram-scale operations. A mechanistic model accounting for the observed selectivity levels and trends is proposed.
Analytical evaluation of plasma serotonin and sphingosine 1-phosphate and their clinical assessment in early atherosclerosis (2012)

Plasma serotonin was inversely correlated with FMD and a decrease in plasma serotonin was inversely correlated with an increase in plasma S1P after statin treatment. The results suggested that plasma levels of serotonin and S1P may be useful for the assessment of endothelial function of patients with low-to-moderate risks of atherosclerotic diseases.
Biosynthesis of vitamin B12: structure of the ester of a new biosynthetic intermediate, precorrin-6y (1992)

13 C Labelling and NMR experiments establish the structure of precorrin-6y octamethyl ester, the corresponding octa-acid being a further new intermediate on the biosynthetic pathway to hydrogenobyrinic acid 1.
Proceedings of the 2017 AdKDD & TargetAd Workshop (2017)

Proceedings of the 2017 AdKDD and TargetAd Workshop held in conjunction with the 23rd ACM SIGKDD Conference on Knowledge Discovery and Data Mining Halifax, Nova Scotia, Canada.
Zinc Titanate Nanopowders. Synthesis and Characterization (2021)

Abstract Zinc titanates nanopowders viz.; Zn 2 TiO 4 , ZnTi 3 O 8 and ZnTiO 3 were synthesized through the thermal decomposition course of ZnC 2 O 4 .2H 2 O-TiO 2 precursor (1:1 mole ratio), prepared via a new co-precipitation method up to 900 o C. Thermogravimetric measurement (TG) was utilized to characterize the precursor decomposition while X-ray diffraction (XRD), Fourier transform infra-red (FT-IR) were used to characterize the decomposition products as well as the phase transitions at different temperatures. XRD revealed the starting of titanates formation at 700 o C via detecting Zn 2 TiO 4 along with ZnO and TiO 2 (anatase) diffraction peaks. By increasing the calcination temperature to 800 o C, the ZnO content vanished with the appearing of Zn 2 Ti 3 O 8 besides ZnTi 2 O 4 and impurities of TiO 2 (anatase). Finally at 900 o C, the Zn 2 Ti 3 O 8 content was decomposed into ZnTiO 3 . Nitrogen adsorption-desorption isotherm of the calcined precursor at 900 o C indicated low specific surface area of 7.1 m 2 g -1 in accordance with the agglomeration nature estimated via transmission electron microscopy (TEM) study. The conductivity measurements showed semiconducting behavior of the prepared titanates with ferroelectric transition in the range 200-308 o C.The obtained low dielectric value suggests the uses of present titanates as a co-fired ceramic or resonator ceramics.