gebhart/patrepeval huggingface dataset:
Electron Dynamics of Silicon Surface States: Second-Harmonic Hole Burning on \nSi(111)7x7 (2005)

The ultrafast dynamics of electronic excitations of the surface dangling bond states of Si(111) 7x7 has been investigated by second harmonic generation as a probe of transient spectral hole burning. Spectral holes induced by a 100 fs pump at \\simeq 1.5 eV and their decay are interpreted in terms of electronic dephasing times as short as 15 fs. This fast time scale together with the strong excitation-induced dephasing observed is interpreted in terms of carrier-carrier scattering. In addition, strong coupling of the electronic excitation to surface optical phonons is observed and attributed to the localization at adatom sites of a surface electronic excitation and a surface phonon mode.
LA TOSSINA BOTULINICA NELL'IPERIDROSI (2008)

Un’indagine epidemiologica recente condotta negli Stati Uniti ha rivelato che la iperidrosi focale è presente in 2,8% della popolazione in generale senza differenze significative nei due sessi. L’iperidrosi può essere semplicemente definita, in base a un criterio di tipo topografico, come focale (ascellare, palmare, plantare o frontale) o generalizzata. In letteratura, il trattamento di prima scelta dell’iperidrosi ascellare moderata è rappresentato dal Cloruro di Alluminio al 25% in soluzione alcolica. La ionoforesi sembra possa interrompere la secrezione da parte delle ghiandole eccrine.&#13;\nI farmaci sistemici principalmente utilizzati nel trattamento dell’iperidrosi focale sono gli anticolinergici che vanno ad interferire con la trasmissione neuroghiandolare. Un altro farmaco utilizzato per via intradermica impiegato da circa 10 anni è la tossina botulinica di tipo A che agisce bloccando a livello sinaptico lo stimolo nervoso.
TiO2 Nanowire-Supported Sulfide Hybrid Photocatalysts for Durable Solar Hydrogen Production (2018)

As the feet of clay, photocorrosion induced by hole accumulation has placed serious limitations on the widespread deployment of sulfide nanostructures for photoelectrochemical (PEC) water splitting. Developing sufficiently stable electrodes to construct durable PEC systems is therefore the key to the realization of solar hydrogen production. Here, an innovative charge-transfer manipulation concept based on the aligned hole transport across the interface has been realized to enhance the photostability of In<sub>2</sub>S<sub>3</sub> electrodes toward PEC solar hydrogen production. The concept was realized by conducting compact deposition of In<sub>2</sub>S<sub>3</sub> nanocrystals on the TiO<sub>2</sub> nanowire array. Under PEC operation, the supporting TiO<sub>2</sub> nanowires functioned as an anisotropic charge-transfer backbone to arouse aligned charge transport across the TiO<sub>2</sub>-In<sub>2</sub>S<sub>3</sub> interface. Because of the aligned hole transport, the TiO<sub>2</sub> nanowire-supported In<sub>2</sub>S<sub>3</sub> hybrid nanostructures (TiO<sub>2</sub>-In<sub>2</sub>S<sub>3</sub>) exhibited improved hole-transfer dynamics at the TiO<sub>2</sub>-In<sub>2</sub>S<sub>3</sub> interface and enhanced hole injection kinetics at the electrode surface, substantially increasing the long-term photostability toward solar hydrogen production. The PEC durability tests showed that TiO<sub>2</sub>-In<sub>2</sub>S<sub>3</sub> electrodes can achieve nearly 90.9% retention of initial photocurrent upon continuous irradiation for 6 h, whereas the pure In<sub>2</sub>S<sub>3</sub> merely retained 20.8% of initial photocurrent. This double-gain charge-transfer manipulation concept is expected to convey a viable approach to the intelligent design of highly efficient and sufficiently stable sulfide photocatalysts for sustainable solar fuel generation.
Epiphyseal dysplasia, microcephaly, nystagmus, and retinitis pigmentosa (1989)

In 1975, we reported two brothers with epiphyseal dysplasia, microcephaly, and nystagmus; one of them also had mild mental retardation. Here we present information on the natural history, particularly with respect to the development of a new visual problem, namely, retinitis pigmentosa.
New class of nonlinear optical crystals among arginine salts (2002)

A considerable number of new crystalline compounds were prepared by reacting L-arginine (L-Arg) with a series of inorganic and organic acids. In addition to the usual arginine slats with composition L-Arg-HX, where HX represents various acids, an entirely new class of crystal with the composition L-Arg 2HX was discovered. Due to the presence of the optically active L-arginine component, all these crystal had non-centro-symmetric structures. Most of the crystal prepared in this study gave strong phase-matched second harmonic generation signals with a Nd:YAG laser, and some appear quite promising for nonlinear optical applications.
Encapsulated microenergetic material (2023)

Providing high energy materials that can be placed in previously created fractures and activating them in place to extend or change an existing fracture system. Also detecting the location of fractures or permeable pathways and a means to assess the extent and efficiency of proppant emplacement.
On the practicality of elliptic curve cryptography for medical sensor networks (2014)

Biomedical sensors have long been used to monitor patients in hospitals and emergency settings. Until recently, these sensors were connected to their respective monitors through an array of cumbersome wires. Recent research has made it possible for biomedical sensors to communicate over wireless links, creating new opportunities for patients and caregivers. Not only can the hassle of physical wires be eliminated, but wireless communication has enabled the ability for sensors to form ad-hoc mesh networks with each other. With wireless communication, however, effective secure communication must now become a priority in countries like the United States where a patient's privacy is mandated by law. Until now, security in biomedical sensor networks has been provided by symmetric key cryptography. While computationally efficient, pre-shared keys introduce the new obstacles of key management, deployment and protection. Public key cryptography is typically used as a solution to this overhead, but has not been feasible on remote sensors due to their limited computational resources. To this end, TinyECC is a public key algorithm with optimizations for resource constrained hardware platforms. In this paper, we implement a prototype biomedical sensor application implementing TinyECC to secure the wireless communication between sensor nodes, and study the feasilbility of using TinyECC in a real-time sensor network.
ChemInform Abstract: Mono‐ and Trifluorination of the Thiazole Ring of 2,5‐Diarylthiazoles Using N‐Fluorobenzenesulfonimide (NFSI). (2013)

Abstract A direct selective halogenation of the heterocycle becomes possible under optimized conditions; however, only low yields of the targets are isolated.
Exposure to aluminium and the subsequent development of a disorder with features of Alzheimer's disease (2006)

Increased efforts towards surveillance of people exposed to aluminium in Camelford is necessary to correctly identify the relationship of the exposure to increasing risks of the development of Alzheimer's disease.
Constant Quality Variable Bit-Rate control for SVC (2010)

The article describes a Constant Quality (CQ) Variable Bit-Rate (VBR) control algorithm for multiple layer coding. The goal of VBR mode encoding is saving bits during low complexity scenes to reuse them in higher complexity scenes if necessary, in order to maintain a constantly high visual quality within the bit-rate limits, during the whole encoding process. The proposed single-pass, real time VBR control technique is suitable for temporal, spatial and quality scalability options of the Scalable Video Coding standard. The article supports the effectiveness of the proposed algorithm with many experimental results for both single and multiple layer coding.
Amyloidosis and Waldenstrom’s Macroglobulinemia (2004)

Primary systemic amyloidosis is an immunoglobulin light chain disorder that is 1/5th as common as multiple myeloma. Amyloidosis is regularly seen in the practice of a hematologist and has recently undergone major advances in terms of the ability to evaluate responses as well as new therapeutic options that were not available when this topic was covered as an education session at the American Society of Hematology meeting 5 years ago. Waldenström macroglobulinemia (WM) is rarer than amyloidosis (1500 per year WM versus 3000 per year amyloid in the US), and recent consensus panels have established the definition of the disease, the diagnostic criteria, criteria for initiation of therapy and a new classification scheme. In this session, new developments in amyloid and macroglobulinemia, from suspicion of the diagnosis to treatment, are covered. In Section I, Dr. Morie Gertz answers four specific questions: (1) When should amyloidosis be suspected? (2) How does one heighten ones index of suspicion for amyloid? (3) How is the diagnosis confirmed and the type classified as primary? (4) What is the prognosis and how is it accurately assessed? Recent findings on cardiac biomarkers, presenting features and use of the free light chain assay are reviewed. Staging for amyloid and recently proposed criteria of response and progression are covered. In Section II, Dr. Giampaolo Merlini comprehensively reviews therapy of amyloidosis from the use of standard melphalan/prednisone to the recently described standard dose therapies including dexamethasone, thalidomide/dexamethasone, melphalan/dexamethasone and IV melphalan/dexamethasone. An extensive discussion of the role of high-dose therapy with stem cell reconstitution follows and includes patient selection, predictors of immediate morbidity and mortality, and survival expectation. Finally, a therapeutic strategy is proposed. In Section III, Drs. Steven Treon and Giampaolo Merlini review the most current information on WM. The consensus panel results and recommendations of the clinical pathologic definition of WM, the prognostic markers and the indications to initiate therapy in WM, the uniform response criteria in WM and available treatments for the disease are reviewed. Drs. Treon and Merlini cover recently published treatment protocols that use rituximab, purine nucleoside analogs, and alkylating agents. The current data on thalidomide, alpha interferon, and high-dose therapy are also covered.
Supplementary Figures S1-S6 from Castration Resistance in Prostate Cancer Is Mediated by the Kinase NEK6 (2023)

&lt;p&gt;Androgen-independent tumor formation mediated by NEK6 requires its kinase activity and is not affected by AR silencing (S1); Immunohistochemistry of NEK6 in LHSR-AR xenografts and in human primary prostate cancers (S2); NEK6 does not increase androgen receptor transcriptional activity in LNCaP cells or LHSR-AR cells in vitro (S3); NEK6 overexpression does not increase levels of nuclear beta-catenin in vivo, nor phosphorylation of putative substrates p70S6K and STAT3 (S4); NEK6 overexpression does not lead to promotion of cell cycle progression or antagonism of the p53 pathway in LHSR-AR cells (S5); NEK6 overexpression leads to increased expression of keratin 13 after castration in vivo (S6).&lt;/p&gt;
Comparison of Patient Reported Outcome Measurement Information System With Neck Disability Index and Visual Analog Scale in Patients With Neck Pain (2018)

3.
Pub-Med-dot-com, here we come! (2016)

As of April 8, 2016, articles in Neurology® Genetics can be searched using PubMed. Launched in 1996, PubMed is a search engine that accesses citations and abstracts of more than 26 million articles. Its primary sources include the MEDLINE database, which was started in the 1960s, and biomedical and life sciences journal articles that date back to 1946. In addition, PubMed accesses other sources, for example, citations to those life sciences journals that submit full-text articles to PubMed Central (PMC). PubMed Central was launched in 2000 as a free archive of biomedical and life science journals.
p53 and Her-2/neu in juvenile angiofibromas (2005)

The pathogenesis of juvenile angiofibroma (JA) remains unsolved. Further, it is unknown whether this fibrovascular tumour arises from the endothelial or stromal cells. Comparative genomic hybridisation analysis of these tumours revealed deletions of chromosome 17, including regions for the tumour suppressor gene p53 as well as the Her-2/neu oncogene, which are altered in many human tumours. In order to analyse if they are also important for progression of JA, the p53 gene and Her-2/neu gene were evaluated in 7 tumours by two-colour in situ hybridisation analysis using probes for the centromer of chromosome 17 either with a specific probe against p53 or Her-2/neu. In 5 out of 7 JAs, gene losses were detected for both genes ranging from 10.5 to 31.5%, respectively. Gene amplifications were not observed. Semi-quantitative RT-PCR analysis from laser microdissected single endothelial cells and fibroblasts showed up-regulated p53 mRNA levels in 4 out of the 7 JAs analysed in both investigated cell types and in one case in only endothelial cells. Her-2/neu mRNA was noted to be up-regulated in 2 JAs and down-regulated in 1 JA for both cell types. Western blot analysis as well as immunohistochemistry detected no p53 protein in the 5 investigated JAs, indicating absence of mutated p53. Our findings indicate that chromosomal losses on chromosome 17 imply p53 gene and Her-2/neu gene losses in JAs. However, comparison of p53 and Her-2/neu mRNA levels in laser microdissected endothelial and stromal cells were not conclusive to answer the question of the tumour cell of origin in JA.
Geometric and optical stereospecificity exhibited by cobalt(III) complexes derived from dl-4-methyl-1,8-diamino-3,6-dithiaoctane (1970)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTGeometric and optical stereospecificity exhibited by cobalt(III) complexes derived from dl-4-methyl-1,8-diamino-3,6-dithiaoctaneJay H. Worrell, Thomas E. MacDermott, and Daryle H. BuschCite this: J. Am. Chem. Soc. 1970, 92, 11, 3317–3325Publication Date (Print):June 1, 1970Publication History Published online1 May 2002Published inissue 1 June 1970https://pubs.acs.org/doi/10.1021/ja00714a014https://doi.org/10.1021/ja00714a014research-articleACS PublicationsRequest reuse permissionsArticle Views43Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
A 2.95mW/element Ka-band CMOS Phased-Array Receiver Utilizing On-Chip Distributed Radiation Sensors in Low-Earth-Orbit Small Satellite Constellation (2023)

Small satellite technology has the potential to further extend the current satellite constellation in low-earth orbit (LEO) by realizing a wider coverage and more robust networks all over the world. Compared with conventional satellites, small satellites can drastically reduce launch costs and increase the number of satellites in LEO. However, small satellites face the more severe issues in terms of power consumption and radiation tolerance due to the limited size of solar panels and more than ten times thinner radiation shield than conventional sizeable satellites. In addition, since the small satellites cannot have the large-size antenna installed on the main body, a deployable membrane is attached to the main body for the large phased-array antenna. In that case, the radiation degradation by total ionizing dose (TID) becomes non-uniform due to the shadowing by the main body. The non-uniform gain dropping in the phased-array causes a degradation of beam-pattern performance. Figure 19.3.1 shows an estimated result for the conventional design regarding the non-uniform gain degradation, resulting in 3.1dB main-lobe degradation for one year. Thus, a phased-array receiver with on-chip distributed TID sensors is proposed in this work to solve the non-uniform gain degradation. Compared with the conventional received-signal-strength-indicator-based gain detector, the proposed on-chip distributed TID sensors detect the gain variations between chips and the gain variations inside the chip with radiation hardness features. Thus, the influence on the beampattern can be mitigated by the compensation feedback and distributed TID sensors.
Porous Electrospun Fibers Embedding TiO2 for Adsorption and Photocatalytic Degradation of Water Pollutants (2018)

Using a bipolymer system consisting of polyvinylpyrrolidone (PVP) and poly(vinylidene fluoride) (PVDF), P25-TiO<sub>2</sub> was immobilized into thin film mats of porous electrospun fibers. Pores were introduced by dissolving sacrificial PVP to increase surface area and enhance access to TiO<sub>2</sub>. The highest photocatalytic activity was achieved using a PVDF:PVP weight ratio of 2:1. Methylene blue (MB) was used to visualize contaminant removal, assess the sorption capacity (5.93 ± 0.23 mg/g) and demonstrate stable removal kinetics ( k<sub>MB</sub> > 0.045 min<sup>-1</sup>) under UVA irradiation (3.64 × 10<sup>-9</sup> einstein/cm<sup>2</sup>/s) over 10 cycles. Treatment was also accomplished via sequential MB sorption in the dark and subsequent photocatalytic degradation under UVA irradiation, to illustrate that these processes could be uncoupled to overcome limited light penetration. The photocatalytic mat degraded bisphenol A and 17α-ethynylestradiol in secondary wastewater effluent (17 mg TOC/L), and (relative to TiO<sub>2</sub> slurry) immobilization of TiO<sub>2</sub> in the mat mitigated performance inhibition by co-occurring organics that scavenge oxidation capacity. This significantly lowered the electrical energy-per-order of reaction (EEO) needed to remove such endocrine disruptors in the presence of oxidant scavenging/inhibitory organics. Thus, effective TiO<sub>2</sub> immobilization into polymers with affinity toward specific priority pollutants could both increase the efficiency and reduce energy requirements of photocatalytic water treatment.
Cyclin-dependent kinase inhibitors: a survey of the recent patent literature (2005)

Since the mid-1990s cyclin-dependent kinase (CDK) inhibition has been the subject of an intense drug discovery effort in the pharmaceutical industry and in some academic institutions. Although only few compounds have at present progressed into human clinical trials, the prospect of finding safe agents useful in therapy, particularly in the cancer setting, is still positive. Some trends can be observed that witness the impact of recent findings in CDK basic biological research and technology advancements on the evolution of the patent literature on CDK inhibition. A patent literature review of small organic molecules as CDK inhibitors comprising the years 2001 – 2004 is presented here, as many of the major pharmaceutical companies have shown a continued effort in the field.
Column Agglutination Assay Using Polystyrene Microbeads for Rapid Detection of Antibodies against SARS-CoV-2 (2022)

Rapid serology platforms are essential in disease pandemics for a variety of applications, including epidemiological surveillance, contact tracing, vaccination monitoring, and primary diagnosis in resource-limited areas. Laboratory-based enzyme-linked immunosorbent assay (ELISA) platforms are inherently multistep processes that require trained personnel and are of relatively limited throughput. As an alternative, agglutination-based systems have been developed; however, they rely on donor red blood cells and are not yet available for high-throughput screening. Column agglutination tests are a mainstay of pretransfusion blood typing and can be performed at a range of scales, ranging from manual through to fully automated testing. Here, we describe a column agglutination test using colored microbeads coated with recombinant SARS-CoV-2 spike protein that agglutinates when incubated with serum samples collected from patients recently infected with SARS-CoV-2. After confirming specific agglutination, we optimized centrifugal force and time to distinguish samples from uninfected vs SARS-CoV-2-infected individuals and then showed concordant results against ELISA for 22 clinical samples, and also a set of serial bleeds from one donor at days 6-10 postinfection. Our study demonstrates the use of a simple, scalable, and rapid diagnostic platform that can be tailored to detect antibodies raised against SARS-CoV-2 and can be easily integrated with established laboratory frameworks worldwide.
1129: Primary Cryosurgical Ablation of the Prostate (TCAP): 8-Year Experience (2006)

You have accessJournal of UrologyDiscussed Poster, Tuesday, May 23, 2006, 9:00 am - 12:00 pm1 Apr 20061129: Primary Cryosurgical Ablation of the Prostate (TCAP): 8-Year Experience Aaron E. Katz, Brian Stone, Kristofer Prepelica, and Puneet Masson Aaron E. KatzAaron E. Katz More articles by this author , Brian StoneBrian Stone More articles by this author , Kristofer PrepelicaKristofer Prepelica More articles by this author , and Puneet MassonPuneet Masson More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)33354-8AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1129: Primary Cryosurgical Ablation of the Prostate (TCAP): 8-Year Experience." The Journal of Urology, 175(4S), p. 363 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 363 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Aaron E. Katz More articles by this author Brian Stone More articles by this author Kristofer Prepelica More articles by this author Puneet Masson More articles by this author Expand All Advertisement PDF DownloadLoading ...
Effect of Cocoa Flavanols and Their Related Oligomers on the Secretion of Interleukin-5 in Peripheral Blood Mononuclear Cells (2002)

We previously showed that flavanols and their related oligomers (FLO) isolated from cocoa can have immunomodulatory effects on production of the cytokines interleukin-1beta (IL-1beta), IL-2, and IL-4. In the present study, we examined whether selected FLO fractions isolated from cocoa (monomer through decamer) modulate IL-5 protein secretion from resting and phytohemagglutinin (PHA)-stimulated peripheral blood mononuclear cells (PBMC). Although FLO fractions were unstimulatory for IL-5 secretion in resting cells, PHA-induced IL-5 release from PBMC was markedly affected by certain FLO fractions. The monomeric and small oligomeric (dimer and trimer) fractions enhanced PHA stimulation by 50%, 54%, and 43%, respectively. In contrast, the larger oligomeric fractions (hexamer through decamer) inhibited IL-5 release in the range of 18% to 39%; the tetramer and pentamer showed intermediate effects. The increment in IL-5 suggests that FLO may preferentially stimulate immunoglobulin A. We suggest that in the oral cavity this could result in reduction in the risk for dental caries and periodontal disease. This work offers additional data for consideration of the health benefits of dietary FLO from a variety of foods, including those benefits associated specifically with consumption of some cocoas and chocolates.