gebhart/patrepeval huggingface dataset:
Analytical Closed-Form Estimation of Position Error on ZUPT-Augmented Pedestrian Inertial Navigation (2018)

We present an analytical relation between the position estimation uncertainty and inertial measurement unit (IMU) characteristics during zero-velocity-update (ZUPT) augmented pedestrian inertial navigation. The effect of angle random walk of gyroscopes and velocity random walk of accelerometers in IMU on circular error probable is studied. Numerical simulation of the ZUPT-augmented navigation algorithm is conducted based on a generated pedestrian trajectory to verify the analytical results, showing the discrepancy less than 15%, which supports the fidelity of the results. Experiments are also conducted, and the results match our analytical prediction, with the error less than 20%. This study offers a closed-form analytical expression to predict the performance of ZUPT-augmented pedestrian inertial navigation.
Synchronous multimodal combination of full-field OCT and structured illumination fluorescence microscopy(Conference Presentation) (2016)

FF-OCT is a full field high transverse resolution version of temporal domain OCT. It acquires En-face images with an isotropic 3D submicronic resolution deep inside a biological tissue. It can access an optical contrast at a given depth, meaning that FF-OCT is sensitive to variations of optical index. FF-OCT can thus probe the microarchitecture of a tissue without label. However, Ff-OCT lacks of specific molecular contrast. On the contrary, Fluorescence microscopy can reveal labelled molecules with a very good specificity. Structured Illumination Microscopy (SIM) is a technique providing optical sectioning to fluorescence widefield microscopy. However, this technique can be complicated to implement in a tissue, and fails at providing environmental information. Therefore, combining FF-OCT and SIM has many advantages and adds a specific molecular contrast to a microarchitecture image of a biological sample. Combining FF-OCT and SIM has already been reported in the literature. Here, we report on the development of different way to combine FF-OCT and SIM. On the contrary to previously described setups, our setup enables the synchronous detection of both modalities. We believe this is important to access to dynamical events that take place in tissues. With such a technique, we are able to detect fast changes happening both in the environment, and in the behavior of a specific molecule. For now, we applied our technique to detect static structural information in the cornea. By the time of the conference, we expect to use our system to detect dynamical changes in a tissue.
High-Density IgE Recognition of the Major Grass Pollen Allergen Phl p 1 Revealed with Single-Chain IgE Antibody Fragments Obtained by Combinatorial Cloning (2015)

The timothy grass pollen allergen Phl p 1 belongs to the group 1 of highly cross-reactive grass pollen allergens with a molecular mass of ∼25-30 kDa. Group 1 allergens are recognized by >95% of grass pollen allergic patients. We investigated the IgE recognition of Phl p 1 using allergen-specific IgE-derived single-chain variable Ab fragments (IgE-ScFvs) isolated from a combinatorial library constructed from PBMCs of a grass pollen-allergic patient. IgE-ScFvs reacted with recombinant Phl p 1 and natural group 1 grass pollen allergens. Using synthetic Phl p 1-derived peptides, the binding sites of two ScFvs were mapped to the N terminus of the allergen. In surface plasmon resonance experiments they showed comparable high-affinity binding to Phl p 1 as a complete human IgE-derived Ab recognizing the allergens' C terminus. In a set of surface plasmon resonance experiments simultaneous allergen recognition of all three binders was demonstrated. Even in the presence of the three binders, allergic patients' polyclonal IgE reacted with Phl p 1, indicating high-density IgE recognition of the Phl p 1 allergen. Our results show that multiple IgE Abs can bind with high density to Phl p 1, which may explain the high allergenic activity and sensitizing capacity of this allergen.
Expression of Pkd2l2 in Testis Is Implicated in Spermatogenesis (2008)

Pkd2l2 is a novel member of the polycystic kidney disease (PKD) gene family in mammals. Prominently expressed in testis, this gene is still poorly understood. In this study, reverse transcription polymerase chain reaction (RT-PCR) results showed a time-dependent expression pattern of Pkd2l2 in postnatal mouse testis. Immunohistochemical analysis revealed that Pkd2l2 encoded a protein, polycystin-L2, which was predominantly detectable in the plasma membrane of spermatocytes and round spermatids, as well as in the head and tail of elongating spermatids within seminiferous tubules in mouse testis tissue sections of postnatal day 14 and adult mice. A green fluorescent fusion protein of Pkd2l2 resided in the plasma membrane of HEK 293 and MDCK cells, suggesting that it functions as a plasma membrane protein. Overexpression of Pkd2l2 increased the intracellular calcium concentration of MDCK cells, as detected by flow cytometry. Collectively, these data indicated that Pkd2l2 may be involved in the mid-late stage of spermatogenesis through modulation of the intracellular calcium concentration.
Data from A Cell Proliferation and Chromosomal Instability Signature in Anaplastic Thyroid Carcinoma (2023)

&lt;div&gt;Abstract&lt;p&gt;Here, we show that the anaplastic thyroid carcinoma (ATC) features the up-regulation of a set of genes involved in the control of cell cycle progression and chromosome segregation. This phenotype differentiates ATC from normal tissue and from well-differentiated papillary thyroid carcinoma. Transcriptional promoters of the ATC up-regulated genes are characterized by a modular organization featuring binding sites for E2F and NF-Y transcription factors and cell cycle–dependent element (CDE)/cell cycle gene homology region (CHR) cis-regulatory elements. Two protein kinases involved in cell cycle regulation, namely, Polo-like kinase 1 (PLK1) and T cell tyrosine kinase (TTK), are part of the gene set that is up-regulated in ATC. Adoptive overexpression of p53, p21 (CIP1/WAF1), and E2F4 down-regulated transcription from the PLK1 and TTK promoters in ATC cells, suggesting that these genes might be under the negative control of tumor suppressors of the p53 and pRB families. ATC, but not normal thyroid, cells depended on PLK1 for survival. RNAi-mediated PLK1 knockdown caused cell cycle arrest associated with 4N DNA content and massive mitotic cell death. Thus, thyroid cell anaplastic transformation is accompanied by the overexpression of a cell proliferation/genetic instability-related gene cluster that includes PLK1 kinase, which is a potential molecular target for ATC treatment. [Cancer Res 2007;67(21):10148–57]&lt;/p&gt;&lt;/div&gt;
Natural Infection of Sorghum by Foxtail Mosaic Virus in Kansas (1999)

Sorghum (Sorghum bicolor) was infected by a mechanically transmissible, flexuous, rod-shaped virus. Antiserum made against the purified virus reacted specifically in enzyme-linked immunosorbent assay to the virus and to the potexvirus foxtail mosaic virus (FoMV), indicating that the sorghum virus was an isolate of FoMV. Comparison of the sorghum isolate (H93) to FoMV PV 139 showed that H93 differed biologically by causing severe symptoms in sorghum, not readily infecting certain barley lines, and causing only faint symptoms in barley. At the molecular level, the capsid of H93 had a mass of 23.9 kDa and 217 amino acid residues compared with 23.7 kDa and 215 residues previously reported for the nucleic acid sequence of FoMV. The amino acid sequences of the two viruses were greater than 96% identical. They varied by having four substitutions, one deletion, and three insertions between residues 66 and 67. This is the first report of natural infection of sorghum by FoMV, thus extending its host range among cereal crops.
Numerical Methods for Engineering An introduction using MATLAB® and computational electromagnetics examples (2020)

The revised and updated second edition of this textbook teaches students to create modeling codes used to analyze, design, and optimize structures and systems used in wireless communications, microwave circuits, and other applications of electromagnetic fields and waves. Worked code examples are provided for key algorithms using the MATLAB technical computing language. The book begins by introducing the field of numerical analysis and providing an overview of the fundamentals of electromagnetic field theory. Further chapters cover basic numerical tasks, finite difference methods, numerical integration, integral equations and the method of moments, solving linear systems, the finite element method, optimization methods, and inverse problems. Developing and using numerical methods helps students to learn the theory of wave propagation in a concrete, visual, and hands-on way. This book fills the missing space of current textbooks that either lack depth on key topics or treat the topic at a level that is too advanced for undergraduates or first-year graduate students. Presenting the topic with clear explanations, relevant examples, and problem sets that move from simple algorithms to complex codes with real-world capabilities, this book helps its readers develop the skills required for taking a mathematical prescription for a numerical method and translating it into a working, validated software code, providing a valuable resource for understanding the finite difference method, the method of moments, the finite element method, and other tools used in the RF and wireless industry.
Deterministic magnetic domain wall motion induced by pulsed anisotropy energy (2020)

Abstract We propose a method to induce deterministic motion of a magnetic domain wall in a nanowire by inducing short strain pulses uniformly along the nanowire. Via inverse magnetostriction, a strain pulse causes the magnetic anisotropy to vary uniformly on a timescale comparable to the magnetisation dynamics. The resultant torque on the magnetic moments within the domain wall cause it to move along the nanowire. Using numerical calculations we analyse in detail the dependence of the domain wall’s motion on the material’s parameters and on the anisotropy pulse profile, and we consider the specific case of the anisotropy induced by voltage pulses applied to a hybrid piezoelectric/ferromagnet device. The method will be applicable to a range of magnetic textures including skyrmions, solitons, and domain walls in antiferromagnets, and is prospective for applications in a range of areas including ultra-energy efficient information storage and processing, communications technologies, position encoding and biomedical science.
FlexiWeb (2015)

To reduce page load times and bandwidth usage for mobile web browsing, middleboxes that compress page content are commonly used today. Unfortunately, this can hurt performance in many cases; via an extensive measurement study, we show that using middleboxes to facilitate compression results in up to 28% degradation in page load times when the client enjoys excellent wireless link conditions. We find that benefits from compression are primarily realized under bad network conditions. Guided by our study, we design and implement FlexiWeb, a framework that determines both when to use a middlebox and how to use it, based on the client's network conditions. First, FlexiWeb selectively fetches objects on a web page either directly from the source or via a middlebox, rather than fetching all objects via the middlebox. Second, instead of simply performing lossless compression of all content, FlexiWeb performs network-aware compression of images by selecting from among a range of content transformations. We implement and evaluate a prototype of FlexiWeb using Google's open source Chromium mobile browser and our implementation of a modified version of Google's open source compression proxy. Our extensive experiments show that, across a range of scenarios, FlexiWeb reduces page load times for mobile clients by 35-42% compared to the status quo.
In situ ellipsometry of Cu surfaces immersed in benzotriazole–hydrogen peroxide solutions (2016)

Abstract In the chemical mechanical polishing (CMP) of Cu, the Cu surface is oxidized and is concurrently removed by the mechanical function of an abrasive. Surface oxidation can lead to severe surface corrosion, and to prevent this, a corrosion inhibitor is added to slurries. Accurate understanding of the competition between oxidation and passivation is essential for advanced Cu CMP technologies. In this work, layer formation on clean Cu surfaces in benzotriazole (BTA), H 2 O 2 , and BTA–H 2 O 2 aqueous solutions was studied by in situ spectroscopic ellipsometry. Time changes of ellipsometric parameters are discussed with respect to BTA and H 2 O 2 concentrations. It was found that the BTA adsorbs onto the Cu surface and the adsorbed BTA transforms into a Cu–BTA complex in about 3 min after the onset of adsorption. The BTA/complex layer passivates the Cu surface against oxidation by H 2 O 2 .
Gabor domain optical coherence microscopy (2009)

In this paper, we present a developing technology targeted at clinical imaging, Gabor Domain Optical Coherence Microscopy (GD-OCM), which combines the high resolution imaging of optical coherence microscopy (OCM), high imaging speed of Fourier domain optical coherence tomography (FD-OCT), and invariant lateral resolution of our custom designed dynamic focusing objective. A high lateral resolution optical design of a dynamic-focusing optical probe with no moving parts, which provides an invariant resolution of currently &lt; 3 &mu;m across a 2mm full-field of view and 2mm imaging depth, is presented. Furthermore, an acquisition scheme (using the probe) that is capable of performing automatic real time data fusion to render an in-focus high resolution image throughout the depth of sample in real time was implemented. 3D imaging of an African frog tadpole is demonstrated at cellular level resolution.
Idiotypic variation in a human B lymphoma cell line. (1990)

The Ig Id of a B cell lymphoma serves as a distinct marker of the malignant clone and thus as a tumor-specific target for antibody therapy. Somatic variation of the Ig genes expressed by B cell tumors can lead to loss of reactivity with anti-Id antibodies and escape of tumors from the therapeutic effects of such antibodies. In our study, we have used anti-Id antibodies to screen for variants within a cell line derived from a patient with a large cell lymphoma of the B cell type. Cells were simultaneously stained on their surface for idiotypic and for isotypic Ig determinants using reagents labeled with different fluorochromes. Tumor cells expressing intact Ig molecules with alteration of their idiotypic determinants were isolated with the fluorescence activated cell sorter. Idiotypic variation was an ongoing process in vitro with Id- variants being generated at a rate of 2.7 x 10(-4)/cell per generation and Ig- cells being produced at a rate of 1.31 x 10(-5)/cell per generation. Subcloned variants expressed subtle differences in reactivity with a panel of three non-cross-blocking anti-Id antibodies. Analysis of Ig gene rearrangements by the Southern blotting technique using a JH probe established that the variants and the original tumor cells were all clonally related. Immunoprecipitation of surface labeled Ig molecules from the variant subclones disclosed major alterations of the lambda-L chains with no gross alterations of the mu-H chains. Related studies have established that the tumor cells undergo rearrangement and expression of new lambda-L chain genes.
<title>Light-emission-based biosensor for detection of food pathogens: a review</title> (2001)

Rapid detection, identification and enumeration of pathogenic microorganisms is highly important to the food industry to address the food safety concerns. Biosensors are devices that promise to achieve these objectives, these analytical devices can accurately and selectively estimate the levels of foodborne pathogens. The most widely applied biosensors are based on the optical properties like absorption, fluorescence, reflection, refraction, dispersion etc. This review is done to provide an overview of optic based biosensor and their application in the area of food safety. Working principles of Surface plasmon resonance , resonant mirror and fiber optic based biosensor are described in the article. Resonant mirror based biosensor has been used for the estimation of S. aureus, it was proven selective for the strain being tested (Cowan-1). Using colloidal-gold conjugates in sandwich assay format increased the sensitivity of the assay. An integrated fiber optic based biosensor is used for detection of Salmonella typhimurium reducing the detection time to 30 min. Fiber optic based biosensors offer advantage of compactness, flexibility, resistance to electrical noise and small probe size.
The Electronic Guidebook: Using Portable Devices And A Wireless Web-based Network To Extend The Museum Experience (2002)

Recent advances in wireless network technologies create the potential to significantly enhance the experience of a visit to a museum. On the exhibit floor, visitors carrying wirelessly connected portable devices can be given opportunities for exploration, sharing, explanations, context, background, analytical tools, and suggestions for related experiences. When these devices are part of a Web-based network, they can help extend the museum visit: in advance, through activities that orient visitors, and afterward, through opportunities to reflect and explore related ideas.
History and Rationale for Continuous Renal Replacement Therapy (2016)

Abstract New therapeutic advances have coped with an increasing clinical demand for adequate and effective renal replacement therapies in the critically ill patient. The history of CRRT is one of the best examples of multidisciplinary progress and collaboration between medical knowledge and industrial technology toward therapy improvement.
First-in-Human Transcatheter Tricuspid Valve Repair in a Patient With Severely Regurgitant Tricuspid Valve (2015)

Transcatheter tricuspid valve repair could become an effective treatment for high-surgical risk patients who are non-responsive to optimal medical therapy.
Performance Analysis of Relay Site Planning Over Composite Fading/Shadowing Channels With Cochannel Interference (2012)

The performance of relay deployments depends significantly on the capacity of the wireless relay link between a relay node (RN) and its serving base station (BS). Exploiting the deployment flexibility of RNs, relay site planning (RSP) can be utilized to overcome the limitations of the relay link. In particular, RSP is carried out by selecting RN deployment locations from a discrete set of alternatives considering the signal-to-interference-plus-noise ratio (SINR) on the relay link as the selection criterion. In this paper, we present an analytical framework for RSP that can be used for planning and dimensioning of two-hop cellular relay networks operating over composite fading/shadowing channels in the presence of cochannel interference. Nakagami–lognormal distribution is used to model the relay link, whereas the access link between a mobile terminal (MT) and its serving RN is modeled by Rician–lognormal distribution. As these composite models do not have closed-form distribution functions, we utilize mixture gamma (MG) distribution to accurately approximate them. Further, the total cochannel interference in the considered multicellular system is approximated using the moment-generating function (MGF) matching method. Accordingly, we present closed-form expressions for the distributions of relay-link SINR, link rates, and end-to-end rate. In addition, RSP is shown to effectively decrease the amount of fading (AoF) and, thus, mitigate the detrimental effects of composite fading/shadowing. Thorough results reveal significant performance improvements, which justify the use of RSP in cellular relay networks.
Improved Pedestrian Dead Reckoning positioning with gait parameter learning (2016)

We consider personal navigation systems in devices equipped with inertial sensors and GPS, where we propose an improved Pedestrian Dead Reckoning (PDR) algorithm that learns gait parameters in time intervals when position estimates are available, for instance from GPS or an indoor positioning system (IPS). A novel filtering approach is proposed that is able to learn internal gait parameters in the PDR algorithm, such as the step length and the step detection threshold. Our approach is based on a multi-rate Kalman filter bank that estimates the gait parameters when position measurements are available, which improves PDR in time intervals when the position is not available, for instance when passing from outdoor to indoor environments where IPS is not available. The effectiveness of the new approach is illustrated on several real world experiments.
FPGA implementation of an optimized NLMS algorithm (2016)

The recently proposed joint-optimized normalized least-mean-square (JO-NLMS) adaptive algorithm employs a variable step-size parameter to achieve both high convergence and low misadjustment. In this paper, an efficient hardware implementation design is proposed, which exploits the key numerical properties of the JO-NLMS algorithm to reduce the hardware workload (corresponding to the adaptive filter's operations), in terms of binary numerical representations and multiplication blocks. Simulation results are provided in an acoustic echo cancellation scenario, using a ModelSIM-Matlab testing platform.
Water-Immersible MEMS scanning mirror designed for wide-field fast-scanning photoacoustic microscopy (2013)

By offering images with high spatial resolution and unique optical absorption contrast, optical-resolution photoacoustic microscopy (OR-PAM) has gained increasing attention in biomedical research. Recent developments in OR-PAM have improved its imaging speed, but have sacrificed either the detection sensitivity or field of view or both. We have developed a wide-field fast-scanning OR-PAM by using a water-immersible MEMS scanning mirror (MEMS-ORPAM). Made of silicon with a gold coating, the MEMS mirror plate can reflect both optical and acoustic beams. Because it uses an electromagnetic driving force, the whole MEMS scanning system can be submerged in water. In MEMS-ORPAM, the optical and acoustic beams are confocally configured and simultaneously steered, which ensures uniform detection sensitivity. A B-scan imaging speed as high as 400 Hz can be achieved over a 3 mm scanning range. A diffraction-limited lateral resolution of 2.4 μm in water and a maximum imaging depth of 1.1 mm in soft tissue have been experimentally determined. Using the system, we imaged the flow dynamics of both red blood cells and carbon particles in a mouse ear in vivo. By using Evans blue dye as the contrast agent, we also imaged the flow dynamics of lymphatic vessels in a mouse tail in vivo. The results show that MEMS-OR-PAM could be a powerful tool for studying highly dynamic and time-sensitive biological phenomena.