gebhart/patrepeval huggingface dataset:
Auslegung von Kompensationssystemen zur interferometrischen Prüfung asphärischer Flächen (1984)

Bei der interferometrischen Prüfung rotationssymmetrischer asphärischer Flächen werden sogenannte Kompensationssysteme verwendet, deren Anpassung an die Asphäre wegen zusätzlicher Verwendung eines Computerhologramms nur näherungsweise erforderlich ist. Beschrieben wird das Vorgehen für den Gaussischen und Seidelschen Entwurf eines ein- und zweilinsigen Kompensationssystems: Die von Einzellinsen abgedeckten Kegelschnittbereiche und Beispiele für die Erweiterung der Bereiche durch zweilinsige Systeme werden diskutiert. An einem Beispiel wird gezeigt, daß bei Abbildung der asphärischen Fläche in das Computerhologramm oftmals eine Gaussische Auslegung genügt. Es werden Beispiele und Hinweise zur Auslegung bei starken Asphären gegeben.
Characterisation of electrophysiological conduction in cardiomyocyte co-cultures using co-occurrence analysis (2011)

Cardiac arrhythmias are disturbances of the electrical conduction pattern in the heart with severe clinical implications. The damage of existing cells or the transplantation of foreign cells may disturb functional conduction pathways and may increase the risk of arrhythmias. Although these conduction disturbances are easily accessible with the human eye, there is no algorithmic method to extract quantitative features that quickly portray the conduction pattern. Here, we show that co-occurrence analysis, a well-established method for feature recognition in texture analysis, provides insightful quantitative information about the uniformity and the homogeneity of an excitation wave. As a first proof-of-principle, we illustrate the potential of co-occurrence analysis by means of conduction patterns of cardiomyocyte-fibroblast co-cultures, generated both in vitro and in silico. To characterise signal propagation in vitro, we perform a conduction analysis of co-cultured murine HL-1 cardiomyocytes and murine 3T3 fibroblasts using microelectrode arrays. To characterise signal propagation in silico, we establish a conduction analysis of co-cultured electrically active, conductive cardiomyocytes and non-conductive fibroblasts using the finite element method. Our results demonstrate that co-occurrence analysis is a powerful tool to create purity-conduction relationships and to quickly quantify conduction patterns in terms of co-occurrence energy and contrast. We anticipate this first preliminary study to be a starting point for more sophisticated analyses of different co-culture systems. In particular, in view of stem cell therapies, we expect co-occurrence analysis to provide valuable quantitative insight into the integration of foreign cells into a functional host system.
Composite Airframe Condition-Aware Maneuverability and Survivability for Unmanned Aerial Vehicles (2011)

ight envelope and associated maneuvers of a vehicle in combination with airframe structural health and load monitoring allows for both service life extension and enhancement. This method determines the maneuverability of the air- craft by fusing information from various distributed sensors using an airframe capability model. The maneuver envelope is adjusted to match the capability, ensuring that the ve- hicle never reaches dangerous or life-reducing load conditions. The method also estimates useful remaining life based on probabilistic cumulative degradation. The ability to tailor the ight of an aircraft, termed condition-aware maneuvering, addresses challenges facing the armed forces' aging aircraft eets by allowing extended use, while also increasing sur- vivability through increased state-awareness. This method can be integrated with existing vehicle health management systems and extended to other UAV subsystems.
Long-term Follow-up of Standard-Dose Pembrolizumab Plus Reduced-Dose Ipilimumab in Patients with Advanced Melanoma: KEYNOTE-029 Part 1B (2020)

Standard-dose pembrolizumab plus reduced-dose ipilimumab demonstrated robust antitumor activity, durable response, and favorable long-term survival with manageable toxicity.
Notice of Removal Impact of distributed PV on demand load forecasts (2017)

Removed.
H1N1 influenza viruses varying widely in hemagglutinin stability transmit efficiently from swine to swine and to ferrets (2017)

A pandemic-capable influenza virus requires a hemagglutinin (HA) surface glycoprotein that is immunologically unseen by most people and is capable of supporting replication and transmission in humans. HA stabilization has been linked to 2009 pH1N1 pandemic potential in humans and H5N1 airborne transmissibility in the ferret model. Swine have served as an intermediate host for zoonotic influenza viruses, yet the evolutionary pressure exerted by this host on HA stability was unknown. For over 70 contemporary swine H1 and H3 isolates, we measured HA activation pH to range from pH 5.1 to 5.9 for H1 viruses and pH 5.3 to 5.8 for H3 viruses. Thus, contemporary swine isolates vary widely in HA stability, having values favored by both avian (pH >5.5) and human and ferret (pH ≤5.5) species. Using an early 2009 pandemic H1N1 (pH1N1) virus backbone, we generated three viruses differing by one HA residue that only altered HA stability: WT (pH 5.5), HA1-Y17H (pH 6.0), and HA2-R106K (pH 5.3). All three replicated in pigs and transmitted from pig-to-pig and pig-to-ferret. WT and R106 viruses maintained HA genotype and phenotype after transmission. Y17H (pH 6.0) acquired HA mutations that stabilized the HA protein to pH 5.8 after transmission to pigs and 5.5 after transmission to ferrets. Overall, we found swine support a broad range of HA activation pH for contact transmission and many recent swine H1N1 and H3N2 isolates have stabilized (human-like) HA proteins. This constitutes a heightened pandemic risk and underscores the importance of ongoing surveillance and control efforts for swine viruses.
Observation of the decay Bc+ -> Bs0 pi+ (2013)

The result of a search for the decay B+c→B0sπ+ is presented, using the B0s→D−sπ+ and B0s→J/ψϕ channels. The analysis is based on a data sample of pp collisions collected with the LHCb detector, corresponding to an integrated luminosity of 1 fb−1 taken at a center-of-mass energy of 7 TeV, and 2 fb−1 taken at 8 TeV. The decay B+c→B0sπ+ is observed with significance in excess of 5 standard deviations independently in both decay channels. The measured product of the ratio of cross sections and branching fraction is [σ(B+c)/σ(B0s)]×B(B+c→B0sπ+)=[2.37±0.31 (stat)±0.11 (syst)+0.17−0.13(τB+c)]×10−3, in the pseudorapidity range 2&lt;η(B)&lt;5, where the first uncertainty is statistical, the second is systematic, and the third is due to the uncertainty on the B+c lifetime. This is the first observation of a B meson decaying to another B meson via the weak interaction.
Tensor Evaluation of Anisotropic Stress Relaxation in Mesa-Shaped SiGe Layer on Si Substrate by Electron Back-Scattering Pattern Measurement: Comparison between Raman Measurement and Finite Element Method Simulation (2013)

A strained SiGe layer will be used in next-generation transistors to improve device performance along with device scaling. However, the stress relaxation of the SiGe layer may be inevitable in nanodevices, because the SiGe layer is processed into a nanostructure. In this study, we evaluated the anisotropic stress relaxation in mesa-shaped strained SiGe layers on a Si substrate by electron backscattering pattern (EBSP) measurement. Moreover, we compared the results of EBSP measurement with those of anisotropic Raman measurement and finite element method (FEM) simulation. As a result, the anisotropic stress relaxation obtained by Raman spectroscopy was confirmed by EBSP measurement. Additionally, we obtained a good correlation between the results of EBSP measurement and FEM simulation. The σ x x and σ y y stresses were markedly relaxed and the σ z z and σ x z stresses were concentrated at the SiGe layer edges. These stresses were mostly relaxed in the distance range from the SiGe layer edges to 200 nm. Therefore, in a SiGe nanostructure with a scale of less than 200 nm, stress relaxation is inevitable. The results of EBSP and Raman measurements, and FEM simulation show a common tendency. We believe that EBSP measurement is useful for the evaluation of stress tensors and is complementary to Raman measurement.
Relative intensity noise characteristics of frequency stabilised grating-coupled modelocked semiconductor laser (2006)

Relative intensity noise (RIN) characteristics of a frequency stabilised grating-coupled modelocked semiconductor laser (MSL) have been experimentally investigated. Reported is the first measurement, to the authors&apos; knowledge, of general RIN characteristics as well as RIN reduction in the frequency stabilised MSL system showing the relationship between RIN and mode coherency in the MSL.
NOVEL MECHANISM OF INHIBITION OF CYTOMEGALOVIRUS BY THE EXPERIMENTAL IMMUNOSUPPRESSIVE AGENT LEFLUNOMIDE1,2 (1999)

These findings imply that leflunomide, an effective immunosuppressive agent, shows potential to concurrently attenuate a major complication of immunosuppression, CMV disease, by a novel mechanism of antiviral activity.
FollowNet: Robot Navigation by Following Natural Language Directions with Deep Reinforcement Learning (2018)

Understanding and following directions provided by humans can enable robots to navigate effectively in unknown situations. We present FollowNet, an end-to-end differentiable neural architecture for learning multi-modal navigation policies. FollowNet maps natural language instructions as well as visual and depth inputs to locomotion primitives. FollowNet processes instructions using an attention mechanism conditioned on its visual and depth input to focus on the relevant parts of the command while performing the navigation task. Deep reinforcement learning (RL) a sparse reward learns simultaneously the state representation, the attention function, and control policies. We evaluate our agent on a dataset of complex natural language directions that guide the agent through a rich and realistic dataset of simulated homes. We show that the FollowNet agent learns to execute previously unseen instructions described with a similar vocabulary, and successfully navigates along paths not encountered during training. The agent shows 30% improvement over a baseline model without the attention mechanism, with 52% success rate at novel instructions.
Toward Semantic-Based Exploration of Parallelism in Production Systems (1994)

We propose a new approach for the parallel execution of production system programs. This approach embodies methods of decomposition abstraction using declarative mechanisms. Application semantics can then be exploited to achieve a much higher degree of concurrency. In this paper we present the underlying object-based framework of production systems and discuss the ensuing semantic-based dependency analysis technique. In particular, we define a new notion of functional dependency to characterize associative relationships among data objects, which can be used to determine concurrently executable rules. A byproduct of this research is a new technique for rapid system development and evaluation. The technique eliminates the possible inaccuracy of simulation as well as the high cost of full-fledged system implementation. 1 Introduction A production system is composed of a working memory, a set of rules, and an inference engine. Working memory is a global database composed of data objects c...
Instability in an amorphous In–Ga–Zn–O field effect transistor upon water exposure (2016)

The instability of an amorphous indium-gallium-zinc oxide (IGZO) field effect transistor is investigated upon water treatment. Electrical characteristics are measured before, immediately after and a few days after water treatment in ambient as well as in vacuum conditions. It is observed that after a few days of water exposure an IGZO field effect transistor (FET) shows relatively more stable behaviour as compared to before exposure. Transfer characteristics are found to shift negatively after immediate water exposure and in vacuum. More interestingly, after water exposure the off current is found to decrease by 1-2 orders of magnitude and remains stable even after 15 d of water exposure in ambient as well as in vacuum, whereas the on current more or less remains the same. An x-ray photoelectron spectroscopic study is carried out to investigate the qualitative and quantitative analysis of IGZO upon water exposure. The changes in the FET parameters are evaluated and attributed to the formation of excess oxygen vacancies and changes in the electronic structure of the IGZO bulk channel and at the IGZO/SiO2 interface, which can further lead to the formation of subgap states. An attempt is made to distinguish which parameters of the FET are affected by the changes in the electronic structure of the IGZO bulk channel and at the IGZO/SiO2 interface separately.
The interaction between bovine herpesvirus type 1 and activated bovine T lymphocytes (1990)

The interaction between activated bovine T lymphocytes (BTLs) and bovine herpesvirus type 1 (BHV-1) was investigated. BHV-1 infection of BTLs reduced the amplitude of recombinant bovine interleukin 2-induced proliferative responses. This decreased proliferation was caused by a virus-induced lymphocytolysis which was dependent on viable virus and was not inhibited by recombinant bovine interferon-alpha I1. Furthermore, lymphocytolysis was not associated with virus replication or with the synthesis of detectable levels of viral proteins. Electron microscopic examination of virus-infected cells revealed that lymphocytolysis was characterized by early nuclear disintegration resembling apoptosis. These observations suggest that activated T cells, localized at the site of BHV-1 infection, may be susceptible to virus-induced cytolysis.
Secure Cooperative Sensing in IEEE 802.22 WRANs Using Shadow Fading Correlation (2011)

Cooperative (or distributed) sensing has been recognized as a viable means to enhance the incumbent signal detection by exploiting the diversity of sensors. However, it is challenging to secure such distributed sensing due mainly to the unique features of dynamic spectrum access networks-openness of low-layer protocol stacks in software-defined radio devices and the absence of interactions/coordination between primary and secondary devices. To meet this challenge, we propose an attack-tolerant distributed sensing protocol (ADSP) for DTV signal detection in IEEE 802.22 WRANs, under which sensors in close proximity are grouped as a cluster, and sensors within a cluster cooperate to safeguard the integrity of sensing. The heart of ADSP is a novel filter based on shadow-fading correlation, by which the fusion center cross-validates reports from the sensors to identify and penalize abnormal sensing reports. By realizing this correlation filter, ADSP significantly reduces the impact of an attack on the performance of distributed sensing, while incurring minimal processing and communication overheads. ADSP also guarantees the detectability requirements of 802.22 to be met even with the presence of sensing report manipulation attacks by scheduling sensing within the framework of sequential hypothesis testing. The efficacy of ADSP is validated on a realistic 2D shadow-fading field. Our extensive simulation-based study shows that ADSP reduces the false-alarm rate by 99.2 percent while achieving 97.4 percent of maximum achievable detection rate, and meets the detection requirements of IEEE 802.22 in various attack scenarios.
Intramolecular hydrogen bonding in acylated 2,2′‐bipyridine‐3,3′‐diamines (1995)

Abstract Various di‐ and monoacylated 2,2′‐bipyridine‐3,3′‐diamines (amides 1a‐f, 8, 9 , ureas 1g‐h, 8b and acylureas 1i‐j ) have been synthesized and characterized. All molecules show strong intramolecular hydrogen bonding between the acyl NH of one ring and the pyridine N‐1 of the other (and vice versa ), as is deduced from the low field 1 H NMR resonances of the acyl NH protons, which range from δ 12.6 to 15.0 ppm in CDCl 3 . The nature of the secondary structure of the (di)acylated 2,2′‐bipyridine‐3,3′‐diamines has been investigated using a variety of techniques including variable‐temperature 1 H NMR and CD spectroscopy.
Radioactive Labelling of Toxin I fromAnemonia sulcataand Binding to Crayfish Nerve in vitro (1980)

1. Radioactive derivatives of neurotoxin I (ATX I) from Anemonia sulcata have been synthesized: Iodination of ATX I with 125I yielded a mixture of reaction products from which monoiodo and diiodo ATX I were isolated. 2. 125I-ATX I was shown to bind to the axonal membrane from Astacus leptodactylus main walking nerve. Specificity of binding was shown by saturability of the binding sites and by competitive binding of native and radioactive toxin. 3. Astacus nerve bound 44 fmol of 125I-ATX I/mg nerve (wet weight). The axonal membrane surface of the nerve was determined to be 7800 cm2/g nerve. This amounts to a binding site density of around 35/mu2 axonal surface. Binding was not inhibited by tetrodotoxin, the blocker of the selectivity filter of voltage-dependent sodium channels. 125I-ATX I therefore may bind to the sodium channel-inactivating gate. 4. The affinity of the nerve membrane receptors for 125I-ATX I appears to be voltage-dependent: KD = 5 nM was found with whole crayfish nerves in the presence of tetrodotoxin, KD = 40nM in the absence of tetrodotoxin and an even lower affinity was obtained with axonal membrane fragments isolated from the nerve. Drugs destabilizing the membrane potential, e.g. veratridine, ouabain and sodium azide lowered the affinity or abolished binding completely.
PhiC31 Integrase for Modification of Stem Cells (2009)

This chapter contains sections titled: Properties Of ΦC31 Integrase in Mammalian Cells Studies Using ΦC31 Integrase in Stem Cells Future Use of ΦC31 Integrase in Generation and Modification of Stem Cells Acknowledgments References
Two-Scale Stochastic Control for Integrated Multipoint Communication Systems With Renewables (2016)

Increasing threats of global warming and climate changes call for an energy-efficient and sustainable design of future wireless communication systems. To this end, a novel two-scale stochastic control framework is put forth for smart-grid powered coordinated multi-point (CoMP) systems. Taking into account renewable energy sources, dynamic pricing, two-way energy trading facilities, and imperfect energy storage devices, the energy management task is formulated as an infinite-horizon optimization problem minimizing the time-averaged energy transaction cost, subject to the users’ quality of service requirements. Leveraging the Lyapunov optimization approach as well as the stochastic subgradient method, a two-scale online control (TS-OC) approach is developed for the resultant smart-grid powered CoMP systems. Using only historical data, the proposed TS-OC makes online control decisions at two timescales, and features a provably feasible and asymptotically near-optimal solution. Numerical tests further corroborate the theoretical analysis, and demonstrate the merits of the proposed approach.
People perception: Attractiveness from shape and motion (2016)

While there exists plenty of work on facial attractiveness only little is known about how the rest of the body determines the perception of another person. We were particularly interested in how the shape of the body and the way it moves contributes to attractiveness. Observers (20 male and 20 female) rated the attractiveness of 50 men and 50 women from the BML database each displayed in either of three ways in a 3D immersive virtual reality: (a) static bodies reconstructed from the motion capture data by means of MoSh (Loper et al. 2014, SIGGRAPH Asia) displayed as detailed 3D shapes ; (b) walking stick-figures (Troje 2002, JOV); (c) same bodies as above, but animated with the corresponding walking movements. Correlations between all 12 sets of ratings (2 participant sex x 2 walker sex x 3 display types) reveal three different factors that contribute to the perception of attractiveness. The first factor is sexual dimorphism and applies to female attractiveness assigned to stick figures and moving meshes. The more feminine a woman, the more attractive she is rated. The second is characterized by increased vertical movement which makes the attractive walker appear bouncy, confident, and vigorous. It dominates male attractiveness assigned to stick-figures and moving meshes. The third factor is characterized by slim, tall body shape (attractive) as compared to stout and wider shapes and applies to ratings of static body shapes of both male and female walkers. Male and female observers agree in all cases. The way we move affects our appeal to others as much as the appearance of the static body. While sexual dimorphism dominates female attractiveness, it does not play much of a role for male attractiveness – neither in the shape nor in the motion domain. Meeting abstract presented at VSS 2016
Fast 3D MR elastography of the whole brain using spiral staircase: Data acquisition, image reconstruction, and joint deblurring (2021)

A novel 3D gradient-echo-based approach has been designed and implemented, and shown to have promising potential for fast and high-resolution in vivo MRE of the whole brain.
Nanocomposites of bacterial cellulose nanofibers and chitin nanocrystals: fabrication, characterization and bactericidal activity (2013)

An environmentally friendly approach was implemented for the production of nanocomposites with bactericidal activity, using bacterial cellulose (BC) nanofibers and chitin nanocrystals (ChNCs). The antibacterial activity of ChNCs prepared by acid hydrolysis, TEMPO-mediated oxidation or partial deacetylation of α-chitin powder was assessed and the structure of the ChNC nanoparticles was characterized by X-ray diffraction, atomic force microscopy, and solid-state 13C-NMR. The partially deacetylated ChNCs (D-ChNC) showed the strongest antibacterial activity, with 99 ± 1% inhibition of bacterial growth compared to control samples. Nanocomposites were prepared from BC nanofibers and D-ChNC by (i) in situ biosynthesis with the addition of D-ChNC nanoparticles in the culture medium of Acetobacter aceti, and (ii) post-modification by mixing D-ChNC with disintegrated BC in an aqueous suspension. The structure and mechanical properties of the BC/D-ChNC nanocomposites were characterized by Fourier transform infrared spectroscopy, elemental analysis, field-emission scanning electron microscopy, and an Instron universal testing machine. The bactericidal activity of the nanocomposites increased with the D-ChNC content, with a reduction in bacterial growth by 3.0 log units when the D-ChNC content was 50%. D-ChNC nanoparticles have great potential as substitutes for unfriendly antimicrobial compounds such as heavy metal nanoparticles and synthetic polymers to introduce antibacterial properties to cellulosic materials.