gebhart/patrepeval huggingface dataset:
Graft Immune Cell Composition Associates with Clinical Outcome of Allogeneic Hematopoietic Stem Cell Transplantation in Patients with AML (2016)

Complications of allogeneic hematopoietic stem cell transplantation (HSCT) have been attributed to immune cells transferred into the patient with the graft. However, a detailed immune cell composition of the graft is usually not evaluated. In the present study, we determined the level of variation in the composition of immune cells between clinical HSCT grafts and whether this variation is associated with clinical outcome. Sizes of major immune cell populations in 50 clinical grafts from a single HSCT Centre were analyzed using flow cytometry. A statistical comparison between cell levels and clinical outcomes of HSCT was performed. Overall survival, acute graft-versus-host disease (aGVHD), chronic graft-versus-host disease (cGVHD), and relapse were used as the primary endpoints. Individual HSCT grafts showed considerable variation in their numbers of immune cell populations, including CD123<sup>+</sup> dendritic cells and CD34<sup>+</sup> cells, which may play a role in GVHD. Acute myeloid leukemia (AML) patients who developed aGVHD were transplanted with higher levels of effector CD3<sup>+</sup> T, CD19<sup>+</sup> B, and CD123<sup>+</sup> dendritic cells than AML patients without aGVHD, whereas grafts with a high CD34<sup>+</sup> content protected against aGVHD. AML patients with cGVHD had received grafts with a lower level of monocytes and a higher level of CD34<sup>+</sup> cells than those without cGVHD. There is considerable variation in the levels of immune cell populations between HSCT grafts, and this variation is associated with outcomes of HSCT in AML patients. A detailed analysis of the immune cell content of the graft can be used in risk assessment of HSCT.
Testicular Cancer (2019)

Testicular cancer accounts for approximately 1% of all cancers in males. Every year approximately 8500 patients are diagnosed with testicular cancer but less than 0.5% die as a result. The most common presenting symptom is a painless swelling of the testicle, associated with dull heavy sensation in lower abdomen. Exact pathogenesis is not known but 80% of all histologic subtypes have an isochromosome of short arm of chromosome 12. There is no proven screening for testicular cancer. Orchiectomy, or a tissue biopsy in the case of an extratesticular mass, is typically required for diagnosis. Treatment modalities include radiation and chemotherapy for seminoma and chemotherapy and retroperitoneal lymph node dissection for nonseminomas. Sometimes, surgical resection of residual masses is required. There is increased focus on avoiding toxicity of treatment in patients with high likelihood of cure.
Construction of Object Grasp Control System by Two Fingers Robot Hand using Visual Feedback (2019)

Currently, reductions in the labor force have become problems. Therefore, automation is advanced in small production which has been conventionally done manually. However, it is still done manually in terms of tasks handling of flexible items such as foods. Therefore, we aim to construct a gripping system that enables soft grip. First, we manufacture robot fingers based on human structure. Secondly, we introduce visual feedback. Finally, we introduce an adaptive controller that is robust against environmental changes. We conduct grasp experiment using two fingers. From the results, we showed that both rigid bodies and flexible objects can be gripped.
Syntheses of polymerizable triacyl-type phosphocholines and their polymerized vesicles. (1988)

分子内に3個の重合性基をもつトリアシル型リン脂質:ο-[2,2,2-トリス(2',4'-アルカジエノイルオキシメチル)エチル]ホスホコリンを合成し,これが形成する二分子膜小胞体(ベシクル)を紫獲光照射により高分子化した。アシル基部分の炭素鎖長12以上のものはベシクルを形成するが,14以上では超音波法でLUVを生成する。高分子化ベシクルは溶媒不溶で,かつ凍結解凍操作や界面活性剤およびリン脂質酵素ホスホリパーゼDの添加に対しいちじるしく安定度が高い。
Enhancing the Specular Effect of Metallic Color Prints by Reducing the Use of Yellow Ink (2011)

The MetallicArt technique is used as a visual security feature to hide patterns in CMY images using an additional silver ink. The patterns are hidden under nonspecular viewing conditions and visible under specular viewing conditions. By varying the amount of silver ink, the authors control the intensity of the specular reflection of the printed pattern. Using a spectral reflection prediction model, they can constrain the maximization of the silver ink (S) in order to keep the color difference between the original CMY color and the fitted CMYS color under a given threshold, ensuring that the pattern is hidden under nonspecular viewing conditions. When the printing device requires the inks to be UV cured, the leafing effect of the silver ink is reduced. This also reduces the specular reflection of the silver ink, which becomes comparable to the specular reflection of the yellow ink. Since both specular reflections are similar, it is difficult to distinguish the embedded patterns under specular viewing conditions when both inks are present. The authors, therefore, propose a new algorithm to embed patterns in CMY images that not only maximizes silver but also minimizes yellow. Experimental results show that the proposed algorithm enhances the visibility of the patterns under specular viewing conditions, allowing the use of MetallicArt when the printing device requires UV curing.
EMI modeling and correlation in a highly integrated package design (2016)

Electromagnetic emission must be properly addressed in complex multi-chip packages (MCM) due to highly miniaturized form-factor requirements. Such modules induce electric and magnetic fields due to high frequency current paths, and if not contained within a susceptible limit, can cause other electronic components to malfunction or compliance failure. Testing for electromagnetic interference (EMI) in the lab after the system is built could be too late. This paper presents an approach to understand the possible EMI sources in a highly integrated complex package system. An EMI simulation methodology has been developed and correlation to near-field measurements is used to establish the accuracy of the simulation. A full wave 3D solver was used to perform the EMI simulation in frequency domain. The emissions were also measured using near-field probes within a shielded chamber. Good correlation was achieved between the measurements and simulations, suggesting benefits of the proposed methodology.
Cardiac interventions under MRI guidance using robotic assistance (2010)

Transapical aortic valve replacement under MRI guidance in a beating heart is a recent minimally invasive technique that could benefit from a surgical assistant system. We present a robotic surgical assistant system that can precisely and repeatably deliver aortic valve prostheses. The surgical system consists of an imaging system, an Innomotion robotic arm, a 3-DoF valve delivery module and user interfaces. Interactive control allows the physician to remain in the loop and adjust the orientation and position using real-time MR feedback. The 3-DoF valve delivery module is developed to deploy both balloon-expandable and self-expanding stented prostheses. We use a new compact fiducial that can be placed close to the volume of interest and requires a single image plane for image based robot registration. We evaluate the MRI compatible valve delivery module for both types of prostheses. The accuracy for prosthesis delivery is about 0.8 mm and 1.5 mm, for self-expanding and balloon-expandable prostheses, respectively. Preliminary results in ex-vivo experimentation suggest that the robotic system can be translated into animal and clinical models.
Wavelength control method of upstream signals using AMCC in WDM-PON for 5G mobile fronthaul (2019)

To meet the 5G mobile traffic demands, many small cells will be installed in the field. A promising candidate for reducing a large number of optical fibers connecting the central and distribution units is a tunable wavelength division multiplexing passive optical network. However, for systems in which multiple wavelengths are transmitted densely such as 100 GHz channel spacing, wavelength setting error and wavelength drift are major issues. In this paper, we describe a wavelength control method that uses an auxiliary management and control channel that complies with ITU-T G.989.3. Our method makes it possible to control the setting error of upstream signals at the initial connection between the optical line terminal and an optical network unit and also to control the wavelength drift due to the aging degradation of the laser diode. We also clarify the control conditions needed to minimize the control time.
FaultLine: Software-Based Fault Injection on Memory Transfers (2021)

Today's integrated memory controllers use complex hardware such as delay-lines to monitor and control signal timings during external memory transfers. Because memory chips with different timing specifications may be used, delay-line tuning registers often remain accessible and programmable from the application processor. In this paper, we introduce FaultLine and the concept of delay-line-based fault injection. First, we demonstrate that by modifying the delay-line calibration value through a simple register access, a malware may induce faults in memory transfers and jeopardize the security of concurrently running assets. Then, we experimentally evaluate the fault injection on an OS-capable system-on-chip by exposing cryptographic applications to corrupted data and retrieving their secret keys. We finally discuss why delay-line-based fault injection should be systematically considered as a potential threat in modern systems where entities with different privileges share external memories.
140A: MECHANICAL STRESSES DETERMINE SCARRING DURING WOUND HEALING (2010)

Bhatt, K; Vial, IN; Wu, K; Wong, V; Dauskardt, R; Longaker, MT; Gurtner, GC Author Information
TLZ (Abstract) (1994)

Z is a formal specification language that describes a system by writing actions–essentially the same kinds of actions that appear in a TLA specification. It was developed by Mike Spivey and others at Oxford for specifying sequential programs. When someone develops a method for sequential programs, they usually think that it will also handle concurrent programs–perhaps by adding an extra feature or two. I had heard that this wasn’t true of the Z developers, and that they were smart enough to realize that Z did not handle concurrency. Moreover, Z is based on mathematics not programming languages, so it is a fairly nice language. TLA assumes an underlying logic for writing actions. The next step was obvious: devise a language for specifying concurrent systems that extends Z with the operators of TLA. Equally obvious was the name of such a language: TLZ. In the Spring of 1991, I visited Oxford and gave a talk on TLA, pointing out how naturally it could be combined with Z. The idea was as popular as bacon and eggs at Yeshiva University. Tony Hoare was at Oxford, and concurrency at Oxford meant CSP. The Z community was interested only in combining Z with CSP–which is about as natural as combining predicate logic with C++. A couple of years later, I was invited to give a talk at the Z User’s Meeting. I dusted off the TLZ idea and presented it at the meeting. Again, I encountered a resounding lack of interest. Had TLA been adopted by the Z community, it might have become a lot more popular. On the other hand, not being attached to Z meant that I didn’t have to live with Z’s drawbacks and was free to design a more elegant language for specifying actions. The result was TLA+, described in [127].
Catalytic System for Homogeneous Ethylene Polymerization Based on Aluminohydride−Zirconocene Complexes (2006)

Ethylene polymerization using catalysts derived from activation of zirconocene aluminohydride complexes with either methyl aluminoxane or B(C6F5)3 is reported. Variable-temperature NMR spectra of mixtures of Cp*2ZrH3AlH2 or Cp‘2ZrH3AlH2 and excess B(C6F5)3 reveal the formation of di- or polynuclear metallocenium ion-pairs featuring terminal or both terminal and bridging borohydride counteranions HB(C6F5)3 arising from hydride abstraction. At higher T, ion-pairs featuring the terminal HB(C6F5)3 counterion decompose, and the AlH3 that is liberated degrades B(C6F5)3 to furnish mixtures of (C6F5)nAlH3-n and, in the case of Cp*2ZrH3AlH2, a new ion-pair partnered with the diborohydride counteranion [Cp*2ZrH][(μ-H)2B(C6F5)2]. The latter compound was independently prepared from Cp*2ZrH2 and HB(C6F5)2 and is active in ethylene polymerization; however it is 1000 times less active than the catalyst formed from Cp*2ZrH3AlH2 and B(C6F5)3 and so cannot account for the multisite behavior of the latter combination. There is evidence of chemical exchange between “free” or terminal HB(C6F5)3and excess B(C6F5)3 in these mixtures, and on the basis of model studies with [nBu4N][HB(C6F5)3] and B(C6F5)3, this involves reversible formation of [nBu4N][(C6F5)3B)(μ-H)B(C6F5)3], which can be detected by 19F NMR spectroscopy in solution at low T.
Determination of absolute thermal rate constants for the charge-transfer reaction DBr+(2∏I,v+)+HBr→HBr+(2∏I′,v′+)+DBr (1992)

The charge transfer reaction DBr+(2∏I,v+,J+)+HBr→HBr+(2∏I′,v′+,J′+)+DBr is studied in a state-to-state manner under thermal conditions in a slowly flowing gas mixture of HBr and DBr. The DBr+ reagent is prepared in a selected vibronic level by using (2+1) resonance-enhanced multiphoton ionization. The HBr+ product is detected in a quantum-state-specific manner using laser-induced fluorescence. From the measurements of the molecular density and the populations of both HBr+ product and DBr+ reagent, the absolute thermal rate constants k(i,v+→i′,v′+) are determined for this charge-transfer process. The rate constants for near-resonant charge transfer in which Δv+=0 and Δi=0 are much large than charge-transfer channels in which either Δi≠0; the smallest rate constants are for those channels in which both Δi≠0 and Δv+≠0. The rotational distribution of the HBr+(i′,v′+) products fits a temperature well in each case. For near-resonant charge transfer, the rotational temperature is slightly warmer than thermal, whereas for nonresonant charge transfer, the rotational temperature is much hotter than thermal. A model in which the excess energy of a charge-transfer process is statistically partitioned among all the degrees of freedom of the complex is able to predict closely the observed rotational temperature.
Thermotropic behavior of celecoxib-loaded beta-casein micelles: relevance to the improved bioavailability (2015)

Abstract The physico-chemical characterization of novel celecoxib-loaded beta-casein micelles (Cx/bCN) was recently described and its superiority in enhancing celecoxib bioavailability after intraduodenal administration to pigs was demonstrated. Here, using solution differential scanning calorimetry (DSC) combined with analysis of size distribution by DLS, zeta potential and changes in composition we demonstrate that the above superiority may be related to the thermotropic behavior of these micelles under physiological conditions. DSC of Cx/bCN reveals a characteristic irreversible exotherm upon heating, having its temperature of maximal change in heat capacity (T m ) at 40–46°C, depending on the Cx/bCN ratio. The higher the Cx/bCN ratio, the lower is T m . While the thermodynamically stable bCN (alone) micelles lack any phase transition, the heat-induced, irreversible structural change of Cx/bCN micelles was associated with almost complete drug release, while micelle diameter and zeta potential decreased. Heating drug-free bCN micelles was effect-less. Altogether, our results suggest that Cx/bCN micelles are metastable supramolecular assemblies that transform upon heating to thermodynamically stable drug-free bCN micelles while releasing their drug-load. These findings also indicate the utility of DSC for future development of bCN micelles as nano-drugs, as well as of other supramolecular-assembly nano-drugs.
A Microtiter Solid Phase Radioimmunoassay for Detection of the Human Reovirus-Like Agent in Stools (1977)

The development of a microtiter solid-phase radioimmunoassay for detection of the human reovirus-like (RVL) agent is described. The test is simple to perform and uses small amounts of reagents; a large number of specimens can rapidly be tested in a single test. Both filtered and unfiltered stool suspensions can be employed. The test was as sensitive as immune electron microscopy, and with an appropriate blocking test, was specific for the human RVL agent.
ChemInform Abstract: ON THE SYNTHESES OF XENON(VI) FLUOROPLUMBATES(IV) AND FLUOROSTANNATES(IV) (1984)

Abstract Durch Umsetzung der Metalldifluoride (Ia) und (Ib) mit Xenonhexafluorid erhält man die entsprechenden Metallate (IIa) und (IIb).
Inverse design of disordered stealthy hyperuniform spin chains (2016)

It has recently been shown that disordered hyperuniform many-particle systems represent new distinguishable states of amorphous matter that are poised between a crystal and a liquid are are endowed with novel physical and thermodynamic properties. Such systems have shown to exist as ground states, i.e., at a temperature of absolute zero. Such ``stealthy'' and hyperuniform states are unique in that they are transparent to radiation for a range of wavelengths. In this paper, we ask whether Ising models of magnets, called spin chains in one dimension, can possess spin interactions that enable their ground states to be disordered, stealthy, and hyperuniform. Using inverse statistical-mechanical theoretical methods, we do demonstrate the existence of such states, which should be experimentally realizable.
Dislocations in LD and LED semiconductor heterostructures (2016)

We discuss misfit dislocations (MDs) and threading dislocations (TDs) in lattice-mismatched semiconductor heteroepitaxial layers, which are the key structural elements of light-emitting diodes (LEDs) and laser diodes (LDs). Novel approaches to modelling MD formation and TD reduction are considered. The behavior of dislocations in conventional III-V semiconductor compounds as well in polar and semipolar III-nitride heterostructures are reviewed in detail.
Numerical Validation of Heat Transfer Augmentation Factor in Serpentine Passages With Ribbed Walls (2010)

The objectives of this study are to validate and calibrate a commercially available CFD code, ANSYS CFX, for aerodynamic and heat transfer predictions in serpentine passages with ribbed walls and to understand the relationship between complex flow fields and heat transfer behavior. The validation was accomplished with the test results of Al-Hadhrami and Han [1] who tested a two-pass, radially outward – 180° bend – radially inward, square serpentine passage with two opposite rib roughened walls. Two configurations of ribs, two Reynolds numbers, two rotational numbers, and two channel orientations were considered for this study. An augmentation factor was used to compare the CFD heat transfer predictions with the experimental results. This augmentation factor is defined as the ratio of the local Nusselt number to that of a fully developed, smooth, circular pipe flow at the same Reynolds number. For the cases studied the CFD predictions were found to match the experimental results within the experimental uncertainty band of 20% except on the leading side of the highest rotational number case where the CFD under predicted the heat transfer augmentation. Streamlines and flow field results obtained at different locations are presented for better understanding of the heat transfer behavior.
Realtime Caustics Using Distributed Photon Mapping (2004)

With the advancements in realtime ray tracing and new global illumination algorithms we are now able to render the most important illumination effects at interactive rates. One of the major remaining issues is the fast and efficient simulation of caustic illumination, such as e.g. the illumination from a car headlight. The photon mapping algorithm is a simple and robust approach that generates high-quality results and is the preferred algorithm for computing caustic illumination. However, photon mapping has a number of properties that make it rather slow on today's processors. Photon mapping has also been notoriously difficult to parallelize efficiently. In this paper, we present a detailed analysis of the performance issues of photon mapping together with significant performance improvements for all aspects of the photon mapping technique. The solution forms a complete framework for realtime photon mapping that efficiently combines realtime ray tracing, optimized and improved photon mapping algorithms, and efficient parallelization across commodity PCs. The presented system achieves realtime photon mapping performance of up to 22 frames per second on non-trivial scenes, while still allowing for interactively updating all aspects of the scene, including lighting, material properties, and geometry.
3C21 Study on Improved Sign Detection System of Flange-Climb Derailment by Real Bogie Flange-Climb Experiment(Safety-Vehicle) (2015)

Railway safety is of vital importance, researchers strive to improve the safety of railway vehicles using various approaches. This paper concerns the development of a sign detection system that detects abnormal conditions leading to the flange-climb derailment of a railway vehicle negotiating a sharp curve at a low speed. This research is the continuation of previous research completed at the University of Tokyo. In previous research, a basic detection algorithm was developed using 1/10-scale vehicle experiments. Following the development of a sign detection algorithm from the scaled model, verification of the sign detection algorithm was then completed using real-scale bogie experiments and Multi-body dynamics simulation. This paper focuses on additional improvements completed on the detection algorithm to shorten the detection time. The improved algorithm was verified by using past situational and experimental data published by Japan Transport Safety Board. Verification of the improved algorithm though conducting experiments using a real-scale bogie is also discussed in this paper.
Effect of irradiance and temperature on photosynthetic activity of the cyanobacteriumMicrocystisspp. (1994)

Abstract The effect of irradiance and temperature on the photosynthetic activity of strains of three Microcystis species, M. aeruginosa K‐5, M. wesenbergii K‐3A, and M. viridis N‐l were investigated. At 25∘C, maximum photosynthetic activities (P max) of the K‐5, K‐3A and N‐l strains were observed under 240, 240 and 60 μE.m‐2 .s‐1, respectively. The Pmax values on a dry weight cell basis, were 4.1, 2.9 and 0.9 μ mol O2. mg dry weight‐1 .h‐1, respectively. The N‐l strain was adapted to a lower irradiance than the K‐5 and K‐3A strains. On a chlorophyll α basis, the Pmax of K‐5, K‐3A and N‐1 strains at 25°C were similar at 210, 240 and 210 μ mol O2.mg chl.a‐1.h‐1, respectively. Thus the lower Pmax per unit dry weight for strain N‐1 seems to be due to its lower chlorophyll a content. The optimum temperature of photosynthetic activity for the K‐5, K‐3A and N‐1 strains were observed at 35°C, 35°C and 20–30°C, respectively. Photosynthetic rates at the optimal temperature were 6.0, 3.8 and 1.9–2.0 μ mol O2. mg dry weight‐1 .h‐1, respectively. The N‐1 strain preferred a lower temperature than the K‐5 and K‐3A strains.
In‐line centrifugal separation of dispersed phases (2007)

Abstract A new device—the rotational particle separator (RPS)—is compared to the cyclone for the removal of ultrafine particles, such as cryogenically condensed contaminant droplets from natural gas. The comparison focusses on identifying for each configuration the smallest size of particle which has a 50% chance of being removed from the gas stream. Whereas a cyclone can only separate 1 μm droplets at very low‐throughputs on the order of 1 MMscfd, at the same energy consumption and device volume, the rotational particle separator removes droplets of that size at throughputs of 300 MMscfd. The advantage of the rotational particle separator, therefore, lies in its compact separation potential for full‐scale industrial gas well throughputs. © 2006 American Institute of Chemical Engineers AIChE J, 2007