gebhart/patrepeval huggingface dataset:
Correction to Flow-Induced Crystallization of Collagen: A Potentially Critical Mechanism in Early Tissue Formation (2017)

ADVERTISEMENT RETURN TO ISSUEPREVAdditions and Correc...Additions and CorrectionsNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Flow-Induced Crystallization of Collagen: A Potentially Critical Mechanism in Early Tissue FormationJeffrey A. Paten, Seyed Mohammad Siadat, Monica E. Susilo, Ebraheim N. Ismail, Jayson L. Stoner, Jonathan P. Rothstein, and Jeffrey W. Ruberti*Cite this: ACS Nano 2017, 11, 8, 8527Publication Date (Web):August 9, 2017Publication History Published online9 August 2017Published inissue 22 August 2017https://pubs.acs.org/doi/10.1021/acsnano.7b05275https://doi.org/10.1021/acsnano.7b05275correctionACS PublicationsCopyright © 2017 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views893Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (108 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Biopolymers,Crystallization Get e-Alerts
Patients' perception about difficulty of treatment with trifluridine/tipiracil and pharmaceutical care: Effectiveness and safety. (2017)

e18249 Background: Trifluridine/tipiracil (TAS) is a new alternative in metastatic colorectal cancer patients (pts) previously treated with fluoropyrimidines, oxaliplatin and irinotecan. Objective:to analyze patients` perception about difficulty of dosage regimen with TAS, the effectiveness and safety. Methods: Retrospective observational study, including pts treated with TAS during expanded access in Spain. Oncology pharmacists, as integral part of cancer team, provide direct patient care medication therapy review, pharmacotherapy management, disease management, medication safety, dispense the medication and other clinical support that may lead to improved quality and clinical outcomes for cancer patient at the beginning of treatment with TAS. About perception we applied a survey with a numeric rating scale (0-10 integers) with 3 questions: difficulty of dosage at the beginning, at the end of 3 rd cycle, and the relevance of the information provided by the oncology pharmacist. Variables studied: sex, age, KRAS status, treatment line, ECOG performance status (PS), dose reduction, previous chemotherapy and adverse events (AE) classified according to CTCAE v4.0. Effectiveness variable: progression-free survival (PFS). Results: 12 pts (10 men; 7 mutated KRAS) were included; median age 60.5 years (range 52-81). TAS line: 3 rd line (4), ≥ 4th (8). PS 1 in 10 patients; 2 pts PS 2. Dose reduction was necessary in 41.7% pts. Currently 5 pts are still alive and in the survey they scored the dosage regimen with ≤5 points at the beginning and the same after 3 cycles. The relevance of, information provided by the oncology pharmacist was evaluated with 10 points. Effectiveness: median PFS 3.1 months (0.5-8.3), 2 pts continue on treatment ( medianfollow-up 8.1 months). Overall survival is not evaluable. Grade 3/4 hemotologic toxicities were most common (anemia 8,3%, neutropenia 25%). Conclusions: The perceived dosage difficulty is low, contrary to expectations. It is important to emphasize the evaluation of the information provided by the oncological pharmacist. Our study supports an effectiviness similar than the efficacy. Hematological is the most important and common toxicity.
Deep Learning based CSI Reconstruction with Limited Feedback for Massive MIMO Systems (2021)

Channel state information (CSI) acquisition is one of the major challenges for massive MIMO systems to enable high efficiency MIMO transmissions. Limited feedback schemes, which quantize CSI into limited number of bits and feed these bits back to the base station (BS), are widely used in real-life mobile networks for BSs to obtain downlink CSI. Practical limited feedback schemes usually have large feedback granularity and introduce severe nonlinear quantization error due to the constraint on feedback overhead. It is hard for legacy signal processing technologies to reconstruct CSI accurately for high efficiency downlink transmissions. Different from the legacy signal processing technologies, deep neural networks trained with big data have strong abilities to fit any nonlinear functions and learn the complex signal model behind the big data, which is a useful tool to solve problems that are nonlinear or hard to be described mathematically. Motivated by these observations, we consider a deep learning based approach for BS receivers to reconstruct CSI based on the limited feedback bits from user equipment (UE). The CSI reconstruction is similar with the image super-resolution which reconstructs a high resolution image from a low resolution one based on the structure information learned by the neural network itself. Performance evaluations demonstrate that the proposed method outperforms the legacy algorithms. The improvement on spectrum efficiency is about 25%. It can also reconstruct the CSI with lower density reference signal (RS) than that in current specification, e.g., the RS density can be 1/32 of current one. Therefore, the reference signal and feedback overhead can be reduced with our method. These results show the potential gain of applying deep learning to physical layer signal processing at the receiver side only, which has little air-interface impact and does not require much effort on enhancing network specifications. Therefore, it is feasible to be deployed in current 5th generation mobile networks with the pace of network evolutions, and opens the gate of intelligent physical layer design for future generations of mobile networks.
Exciton–Polaron‐Induced Aggregation of Organic Electroluminescent Materials: A Major Degradation Mechanism in Wide‐Bandgap Phosphorescent and Fluorescent Organic Light‐Emitting Devices (2015)

The electroluminescence (EL) degradation mechanisms of organic light‐emitting devices (OLEDs) are studied utilizing phosphorescent and fluorescent materials as emitter guests. The results show that these emitter guests, despite being used in low concentrations in OLEDs, aggregate as a result of electrical stress, giving rise to the emergence of new longer‐wavelength bands in their EL spectra after prolonged device operation. Such electrical‐driving‐induced aggregation occurs more significantly in guest materials with wider bandgap ( E g ) and flatter molecular structures. Further investigations reveal that the aggregation process is mainly induced by interactions between excitons and positive polarons that reside on the guests. The findings uncover a previously unknown degradation mechanism that appears to be responsible for the generally much lower EL stability of blue devices relative to their green and red counterparts, especially in case of phosphorescent emitters.
On time-stamp accuracy of passive monitoring in a container execution environment (2016)

Passive monitoring of network performance parameters is experiencing a revival due to widespread adoption of virtualization and software-based implementation of network functions. Timestamping is one of the most challenging operations needed for passively monitoring network traffic performance parameters such as latency and jitter. We develop a setup whereby functions that monitor the network traffic are deployed in monitoring containers adjacently to, and interconnected through a virtual switch with the monitored Virtual Network Function instance. In this scenario, we evaluate the effects of container virtualization and virtual switch mirroring of traffic on the measurement of latency. The evaluation results indicate very low measurement errors (a few microseconds in our testbed) which are consistent over different measurement scenarios, thus validating the feasibility of this technique for passively monitoring latency.
Vector approximate message passing (2017)

The standard linear regression (SLR) problem is to recover a vector x <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sup> from noisy linear observations y = Ax <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sup> + w. The approximate message passing (AMP) algorithm recently proposed by Donoho, Maleki, and Montanari is a computationally efficient iterative approach to SLR that has a remarkable property: for large i.i.d. sub-Gaussian matrices A, its periteration behavior is rigorously characterized by a scalar stateevolution whose fixed points, when unique, are Bayes optimal. AMP, however, is fragile in that even small deviations from the i.i.d. sub-Gaussian model can cause the algorithm to diverge. This paper considers a “vector AMP” (VAMP) algorithm and shows that VAMP has a rigorous scalar state-evolution that holds under a much broader class of large random matrices A: those that are right-rotationally invariant. After performing an initial singular value decomposition (SVD) of A, the per-iteration complexity of VAMP is similar to that of AMP. In addition, the fixed points of VAMP's state evolution are consistent with the replica prediction of the minimum mean-squared error recently derived by Tulino, Caire, Verdú, and Shamai.
Reversal of adriamycin resistance with chimeric anti-ganglioside GM2 antibody (1996)

Ganglioside GM2 is one of the major cell-surface gangliosides expressed in human tumors. We earlier established a mouse/human IgG1 chimeric anti-GM2 antibody, KM966, which displayed anti-tumor activity in human tumor cells both in vitro and in vivo. In this study, we have screened for changes in ganglioside expressions in several drug-resistant human cancer cell lines to examine the modulation of drug resistance by immunotherapy with anti-ganglioside antibodies. Increased GM2 expression, detected by flow cytometry and thin-layer chromatography, was observed in the SBC-3/ADM and AdrR MCF7 adriamycin-resistant cell lines, in contrast with their parental lines. In other related gangliosides, ganglioside GD2 levels in AdrR MCF7 were higher than those in MCF7 cells. We confirmed increased N-acetylgalactosaminyltransferase mRNA in adriamycin-resistant cell lines, as compared with the parental cells, by Northern-blot analysis. Moreover, to investigate the possibility of exploiting the anti-tumor activity of KM966 in order to overcome resistance to adriamycin, we investigated the antibody-dependent cell-mediated cytotoxity of human peripheral mononuclear blood cells and the complement-dependent cytotoxity of human serum with KM966 against SBC-3, SBC-3/ADM, MCF7 and AdrR MCF7. Significantly higher killing via KM966 was observed in SBC-3/ADM and AdrR MCF7 cells as compared with the parental cells. This suggests that passive immunotherapy using KM966 against human adriamycin-resistant cancer may be useful for overcoming resistance to adriamycin.
SINR Analysis of Non-Regenerative Multihop Links with Asymptotically Large Hop Count (2017)

We study the physical-layer performance of a wideband multihop system in which a long chain of amplify-and-forward relays is used for routing orthogonal frequency division multiplexing (OFDM) symbols from a source to a destination. Especially, the symbols are modulated in the source and demodulated in the destination while the relays simply forward respective waveforms with scalar amplification. We first conclude that the power-delay profile (PDP) of the effective end-to-end channel in such a system converges to a specific bell-shaped function when each per-hop channel in the link is modelled with a uniform or exponential PDP. We then derive new closed-form expressions for evaluating the signal-to-interference-and-noise ratio (SINR) of the system in the case of an asymptotically large hop count.
Synthesizing the Compliant Microstructure of Thermally Actuated Materials Using Freedom, Actuation, and Constraint Topologies (2012)

The aim of this paper is to demonstrate how the principles of the Freedom, Actuation, and Constraint Topologies (FACT) synthesis approach may be applied to the design of compliant microstructural architectures that possess extreme or unusual thermal expansion properties (e.g., zero or large negative thermal expansion coefficients). FACT provides designers with a comprehensive library of geometric shapes, which may be used to visualize the regions wherein various microstructural elements can be placed for achieving desired bulk material properties. In this way, designers can rapidly consider and compare every microstructural concept that best satisfies the design requirements before selecting the final design. A screw-theory-based analytical tool is also provided in this paper to help designers calculate and optimize the thermal properties of microstructural concepts, which are generated using FACT. As a case study, this tool is used to calculate the negative thermal expansion coefficient of a microstructural architecture synthesized using FACT.
Highly Conductive Polypropylene–Graphene Nonwoven Composite via Interface Engineering (2017)

Here we report a highly conductive polypropylene-graphene nonwoven composite via direct coating of melt blown polypropylene (PP) nonwoven fabrics with graphene oxide (GO) dispersions in N,N-dimethylformamide (DMF), followed by the chemical reduction of GO with hydroiodic acid (HI). GO as an amphiphilic macromolecule can be dispersed in DMF homogeneously at a concentration of 5 mg/mL, which has much lower surface tension (37.5 mN/m) than that of GO in water (72.9 mN/m, at 5 mg/mL). The hydrophobic PP nonwoven has a surface energy of 30.1 mN/m, close to the surface tension of GO in DMF. Therefore, the PP nonwoven can be easily wetted by the GO/DMF dispersion without any pretreatment. Soaking PP nonwoven in a GO/DMF dispersion leads to uniform coatings of GO on PP-fiber surfaces. After chemical reduction of GO to graphene, the resulting PP/graphene nonwoven composite offers an electrical conductivity of 35.6 S m<sup>-1</sup> at graphene loading of 5.2 wt %, the highest among the existing conductive PP systems reported, indicating that surface tension of coating baths has significant impact on the coating uniformity and affinity. The conductivity of our PP/graphene nonwoven is also stable against stirring washing test. In addition, here we demonstrate a monolithic supercapacitor derived from the PP-GO nonwoven composite by using a direct laser-patterning process. The resulted sandwich supercapacitor shows a high areal capacitance of 4.18 mF/cm<sup>2</sup> in PVA-H<sub>2</sub>SO<sub>4</sub> gel electrolyte. The resulting highly conductive or capacitive PP/graphene nonwoven carries great promise to be used as electronic textiles.
An angiosurgery system using a tripled Nd:YAG laser (1991)

We describe an integrated system for laser treatment of atherosclerosis using 355-nm radiation for ablation and visible light for spectroscopic diagnosis and guidance. Both spectroscopy and ablation share the same fibers in a unique catheter design.
The Recovery of Cognitive Function After Remifentanil- Nitrous Oxide Anesthesia Is Faster than After an Isoflurane-Nitrous Oxide-Fentanyl Combination in Elderly Patients (2000)

Maintenance of anesthesia with remifentanil-nitrous oxide (N(2)O), compared with isoflurane-N(2)O-fentanyl, can safely shorten postoperative recovery of cognitive function in a geriatric population. Earlier recovery may facilitate postoperative neurological assessment. Use of remifentanil-N(2)O for maintenance did not shorten the overall length of stay in the postanesthesia care unit, a stay often related to multiple administrative issues, rather than cognitive recovery.
Atomic layer deposition of hafnium oxide on germanium substrates (2005)

Germanium combined with high-κ dielectrics has recently been put forth by the semiconductor industry as potential replacement for planar silicon transistors, which are unlikely to accommodate the severe scaling requirements for sub-45-nm generations. Therefore, we have studied the atomic layer deposition (ALD) of HfO2 high-κ dielectric layers on HF-cleaned Ge substrates. In this contribution, we describe the HfO2 growth characteristics, HfO2 bulk properties, and Ge interface. Substrate-enhanced HfO2 growth occurs: the growth per cycle is larger in the first reaction cycles than the steady growth per cycle of 0.04nm. The enhanced growth goes together with island growth, indicating that more than a monolayer coverage of HfO2 is required for a closed film. A closed HfO2 layer is achieved after depositing 4–5HfO2 monolayers, corresponding to about 25 ALD reaction cycles. Cross-sectional transmission electron microscopy images show that HfO2 layers thinner than 3nm are amorphous as deposited, while local epitaxial crystallization has occurred in thicker HfO2 films. Other HfO2 bulk properties are similar for Ge and Si substrates. According to this physical characterization study, HfO2 can be used in Ge-based devices as a gate oxide with physical thickness scaled down to 1.6nm.
Homoepitaxial growth of β-Ga2O3layers by halide vapor phase epitaxy (2014)

Thick high-purity β-Ga2O3 layers of high crystalline quality were grown homoepitaxially by halide vapor phase epitaxy (HVPE) using gaseous GaCl and O2 on (001) β-Ga2O3 substrates prepared by edge-defined film-fed growth. The surface morphology and structural quality of the grown layer improved with increasing growth temperature. X-ray diffraction ω-rocking curves for the (002) and (400) reflections for the layer grown at 1000 °C had small full widths at half maximum. Secondary ion mass spectrometry and electrical characteristics revealed that the growth of high-purity β-Ga2O3 layers with low effective donor concentration (Nd − Na < 1013 cm−3) is possible by HVPE.
Evaluation of Augmented Reality Technology in the English Language Field (2015)

Augmented Reality (AR) is heralded to be a promising technology for education. Therefore, it is important to properly evaluate it so practitioners feel more confident in its use. The aims of this study are threefold: (a) to evaluate the use of an AR tool for young children, in the English teaching field concerning linguistic concepts and competencies; (b) to discuss possibilities of use for AR tools in the classroom environment as well as reflect about the potential and difficulties involved in their introduction, and (c) to provide guidelines in order to assist researchers when conducting similar evaluations. The evaluation considered multiple metrics and involved the teacher as an instructional designer. Results supported the hypothesis that AR may help students in the learning process.
Schottky-Ohmic Drain AlGaN/GaN Normally Off HEMT With Reverse Drain Blocking Capability (2010)

In this letter, we propose an AlGaN/GaN normally off high-electron mobility transistor (HEMT) with reverse drain blocking capability. The device features a Schottky-ohmic drain electrode in which a Schottky-controlled normally off channel is inserted between the gate and the conventional ohmic drain contact. Under negative reverse drain bias, the normally off channel provides an energy barrier that effectively blocks the reverse current conduction while contributing only 0.55 V onset voltage in the forward-biased on state. In a device with a gate-drain distance of 9 m, a reverse blocking voltage of -321 V was obtained at V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">GS</sub> = 0 V, comparable with the forward blocking voltage of 351 V; at V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">GS</sub> = 3 V, the reverse blocking voltage was -276 V. The new HEMT also exhibits no degradation in drain saturation current and does not need extra photomask or process steps to fabricate. When forward biased at V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">GS</sub> = 3 V , the proposed device achieved a specific on resistance of 1.97 mΩ · m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
Normobaric oxygen therapy strategies in the treatment of postcraniotomy pneumocephalus (2008)

Administration of postsurgical supplemental O(2) through a nonrebreather mask significantly increases the absorption rate of postcraniotomy pneumocephalus as compared with breathing room air.
3-Oxoindazolinylmethylenephosphoranes from isatic acids (1983)

A. Alemagna, P. D. Buttero, E. Licandro, S. Maiorana and C. Guastini, J. Chem. Soc., Chem. Commun., 1983, 337 DOI: 10.1039/C39830000337
Mantle Cell Lymphoma Genotypes Identified with CGH to BAC Microarrays Define Clinical Subgroups of Disease and Strongly Predict Patient Outcome. (2004)

Abstract Mantle cell lymphoma (MCL) is a rare, aggressive subtype of B-cell non-Hodgkin lymphoma (B-NHL), characterized by t(11;14)(q13;q32). To identify recurrent genomic events involved in the pathogenesis of this malignancy, we used genome-wide comparative genomic hybridization (CGH) to 1.4 Mb. resolution BAC microarrays in 68 patients and 9 derived MCL cell lines; the genome profiles were compared to those from other B-NHL subtypes. Array-CGH defined a MCL genomic signature different from other B-cell lymphomas, including deletions of chromosomes 1p21.2-p12.3, 11q22.3 at ATM gene locus, 13q14.2 and 13q34, with coincident 10p12-BMI locus amplification and 10p14 deletion, along with a previously unidentified loss within 9q21-q22. Specific genomic alterations were associated with different subgroups of disease. Notably, 11 patients with non-nodal, leukemic MCL, defined on the basis of the absence at diagnosis of lymph node disease, showed a different genomic profile to nodal cases, including deletion of 8p21.2 at TRAIL receptor gene cluster (55 vs. 19%;p=0,01) and gain of 8q24.1 at MYC locus (46 vs. 14%;p=0,015). Additionally, leukemic MCL exhibited frequent IgVH mutation (64 vs. 21%;p=0,009) with preferential VH-39 use (36 vs. 4%;p=0,005), and followed a more indolent course, being 7 of 11 patients (64%) survivors for more than 3 years whereas only 15 of 55 patients (27%) in the nodal group experienced this long survival (median survial time, 42 vs. 18 months; p=0,02). The median overall survival (OS) for the patients in the series was 39 months (range, 0–115). Blastoid variant of MCL, increased number of genomic gains, and deletions of P16/INK4a and P53 genes correlated with poorer outcomes, whilst 1p21 loss was associated with prolonged survival (median OS, 70 vs. 31 months; p=0,02). In multivariate analysis, deletion of chromosome 9q21-q22, which has not been previously reported as a common change in MCL, was the strongest predictor for inferior survival (HR:6; CI:2,3–15,7). Last, the genotypes of 14 patients with MCL who were alive for more than 5 years since diagnosis showed deletion of 1p21 in seven cases (50%), but none exhibited deletions of 9q21-q22, 9p21.3-P16/INK4a or 17p13.1-P53. Our study illustrates the utility of array-CGH in MCL sub-classification and highlights the array genomic profile as the strongest indicator for predicting clinical outcome. The screening of this reduced BAC clone set either by FISH or custom-made array CGH devices could be reliably applied to the clinical diagnostics of MCL.