gebhart/patrepeval huggingface dataset:
A Matlab Toolbox for Efficient Perfect Reconstruction Time-Frequency Transforms with Log-Frequency Resolution (2014)

In this paper, we propose a time-frequency representation where the frequency bins are distributed uniformly in log-frequency and their Q-factors obey a linear function of the bin center frequencies. The latter allows for time-frequency representations where the bandwidths can be e.g. constant on the log-frequency scale (constant Q) or constant on the auditory critical-band scale (smoothly varying Q). The proposed techniques are published as a Matlab toolbox that extends [3]. Besides the features that stem from [3] – perfect reconstruction and computational efficiency – we propose here a technique for computing coefficient phases in a way that makes their interpretation more natural. Other extensions include flexible control of the Qvalues and more regular sampling of the time-frequency plane in order to simplify signal processing in the transform domain.
Patients with Inflammatory Bowel Disease Are at Risk for Vaccine-Preventable Illnesses (2006)

Immunization against selected vaccine-preventable illnesses was uncommon in patients with IBD, despite the presence of significant risk factors. Efforts to improve immunization status among patients with IBD and other chronic, immune-mediated conditions are needed.
Wireless and Flexible Optoelectronic System for In Situ Monitoring of Vaginal pH Using a Bioresorbable Fluorescence Sensor (2023)

Abstract Herein, a miniaturized wireless sensing vaginal ring for the in situ continuous monitoring of vaginal pH and real‐time transmission of the pH data to a smartphone is reported, aimed at the diagnosis and management of bacterial vaginosis, a common condition frequently and adversely affecting women. The sensing vaginal ring consists of a bioresorbable pH fluorescence sensor placed on top of a polydimethylsiloxane ring encapsulating a miniaturized driving/readout optoelectronic circuit, data acquisition system, wireless transceiver, and power supply. The pH sensor consists of a micrometer‐thick porous silica scaffold conformably coated with a nanometer‐thick polymer multilayer stack and is intended to be replaced after 4 days. The sensor fully dissolves in biocompatible by‐products eliminating waste management issues; conversely, the ring embedding the circuit is reusable with new sensors. The pH sensor, as well as the sensing vaginal ring, show excellent performance in the continuous measurement of pH in vaginal fluid and can monitor the pH level over the physio‐pathological range of 3–7.5 with high linearity, accuracy, and reliability, transmitting the data to a smartphone in real time. The proposed technology can be immediately translated to other diseases, among which wound healing, intragastric activity, and cancer progression, where continuous monitoring of pH is required, as well as to other markers/analytes by engineering the polymer stack with suitable receptors, such as aptamers and other molecular probes.
Current Concepts in Volar Fixed-angle Fixation of Unstable Distal Radius Fractures (2006)

Level V (expert opinion).
Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development (2022)

Delineating gene regulatory networks that orchestrate cell-type specification is a continuing challenge for developmental biologists. Single-cell analyses offer opportunities to address these challenges and accelerate discovery of rare cell lineage relationships and mechanisms underlying hierarchical lineage decisions. Here, we describe the molecular analysis of mouse pancreatic endocrine cell differentiation using single-cell transcriptomics, chromatin accessibility assays coupled to genetic labeling, and cytometry-based cell purification. We uncover transcription factor networks that delineate β-, α-, and δ-cell lineages. Through genomic footprint analysis, we identify transcription factor-regulatory DNA interactions governing pancreatic cell development at unprecedented resolution. Our analysis suggests that the transcription factor Neurog3 may act as a pioneer transcription factor to specify the pancreatic endocrine lineage. These findings could improve protocols to generate replacement endocrine cells from renewable sources, like stem cells, for diabetes therapy.
Reply to K. Lu (2015)

Comment on: Depth of Invasion in High-Grade T1 Bladder Cancer: Added Value In Timely Cystectomy? [J Clin Oncol. 2015] Improving selection criteria for early cystectomy in high-grade t1 bladder cancer: a meta-analysis of 15,215 patients. [J Clin Oncol. 2015]
Design and Control of an Isolated Bidirectional DC-DC Converter for Hybrid Electric Vehicle Applications (2006)

Hybrid electric vehicles (HEVs) offer many advantages, such as high fuel economy, low emissions, and silent operation. In HEVs, there are two or more different voltage buses for different purposes of the vehicle operation. There are needs of galvanically isolated bidirectional DC-DC converter to link different DC voltage bus and transfer energy back and forth. For example, one of the DC-DC converters convert the high voltage (200-300V) in the main battery to low voltage (-12V) for use in electrical equipment, while the other converts 300V battery voltage and supply the drive motor with 500V. High efficiency, compact size, lightweight, and reliability are all essential requirements for DC-DC converters for electric and hybrid vehicles. This paper introduces a bidirectional, isolated DC-DC converter for medium power applications. A dual full-bridge topology is developed to achieve the power rating. A 1kW prototype of the converter has been built and tested. The experimental results of the converter's steady state operation confirm the simulation analysis. This converter is a first step to understanding the design and build of a medium power DC-DC converter.
Elastic stress domains on the Si(100) surface (1989)

It is proposed that surfaces of crystals that reconstruct with broken orientational symmetry and exhibit an anisotropic stress tensor are unstable to the formation of elastic stress domains. The ground state of such a surface is not uniform, but corresponds to a mosaic pattern of the different domains. This result is applied together with microscopic calculations of surface stress to study the Si(100) surface. A structural transition from single-layer to double-layer steps for vicinal Si(100) surfaces is also studied.
Effect of processing parameters on reaction bonding of silicon nitride (1980)

Reaction bonded silicon nitride was developed. The relationship between the various processing parameters and the resulting microstructures was to design and synthesize reaction bonded materials with improved room temperature mechanical properties.
ChemInform Abstract: Ordered Nanowell Arrays. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Supporting data for Polymeric medical sutures: An exploration of polymers and green chemistry (2014)

These files contain data along with associated output from instrumentation supporting all results reported in Knutson, C. M.; Schneiderman, D. K.; Yu, M.; Javner, C. H.; Distefano, M. D.; Wissinger, J. E. Polymeric medical sutures: An exploration of polymers and green chemistry. J. Chem. Educ. 2017, 94, 1761–1765. In Knutson, et. al. it was found that with new K–12 national science standards emerging, there is an increased need for experiments that integrate engineering into the context of society. Here we describe a chemistry experiment that combines science and engineering principles while introducing basic polymer and green chemistry concepts. Using medical sutures as a platform for investigating polymers, students explore the physical and mechanical properties of threads drawn from poly(ε-caprolactone) samples of different molecular masses and actual purchased absorbable and nonabsorbable medical sutures. An inquiry-based part of the experiment tasks students with designing their own experiment to probe the potential of melt blending poly(ε-caprolactone) with commercially available polylactide products in order to modify the properties of the “sutures” drawn. Through these lessons students gain an appreciation for the importance of plastics in our society and how scientists are working to develop more sustainable alternatives. Overall, this laboratory experiment provides a feasible, versatile, sophisticated laboratory experience that engages students in a relatable topic and meets many of the Next Generation Science Standards.
Continuous TDEV calculation for in-situ synchronisation monitoring in SONET/SDH networks (1993)

C-TDEV is proposed to adapt the block TDEV stability measure from atomic clock metrology to continuous in-situ network synchronisation monitoring. C-TDEV processes TIE samples serially and detects stability fluctuations in the real-time scale of the fluctuations themselves. It yields constant statistical confidence for all observation intervals and requires much less storage than the block calculation.
Expression of the Membrane-associated Carbonic Anhydrase Isozyme XII in the Human Kidney and Renal Tumors (2000)

Carbonic anhydrase isozyme XII (CA XII) is a novel membrane-associated protein with a potential role in von Hippel-Lindau carcinogenesis. Although Northern blotting has revealed positive signal for CA XII in normal human kidney, this is the first study to demonstrate its cellular and subcellular localization along the human nephron and collecting duct. Immunohistochemistry with a polyclonal antibody (PAb) raised against truncated CA XII revealed distinct staining in the basolateral plasma membrane of the epithelial cells in the thick ascending limb of Henle and distal convoluted tubules, and in the principal cells of the collecting ducts. A weak basolateral signal was also detected in the epithelium of the proximal convoluted tubules. In addition to the normal kidney specimens, this immunohistochemical study included 31 renal tumors. CA XII showed moderate or strong plasma membrane-associated expression in most oncocytomas and clear-cell carcinomas. The segmental, cellular, and subcellular distribution of CA XII along the human nephron and collecting duct suggests that it may be one of the key enzymes involved in normal renal physiology, particularly in the regulation of water homeostasis. High expression of CA XII in some renal carcinomas may contribute to its role in von Hippel-Lindau carcinogenesis.
CCR7 Plays No Appreciable Role in Trafficking of Central Memory CD4 T Cells to Lymph Nodes (2013)

CCR7⁻/⁻ mice exhibit profound anomalies in lymph node and spleen architecture, which complicates the study of CCR7-mediated T cell trafficking in vivo. To circumvent this problem, we established in vivo models in which wild-type and CCR7⁻/⁻ populations coexist within mice possessing normal lymphoid organs and must compete for developmental niches within the tissues of these mice. Under the conditions we have created in vivo, we find the entry of memory CD4 T cells into lymph nodes from the blood to be independent of CCR7. Thus, the central memory CD4 T cells that traffic though lymph nodes, which are often defined by their expression of CCR7, do not appear to gain any competitive homing advantage by expressing this receptor. Furthermore, in contrast to cutaneous dendritic cell populations, we found that CCR7 deficiency had no appreciable effect on the exit of CD4 T cells from inflamed skin. Finally, we found that wild-type and CCR7⁻/⁻ precursors were equally represented within the major thymic subpopulations, despite previous findings that CCR7 plays a role in seeding the thymus from bone marrow-derived T cell precursors.
Fabrication of low reflectance optical fibre mirrors (1996)

Low reflectance optical fibre mirrors were fabricated using mechanical splices and pieces of fibre coated at the cleaved end with a TiO2 dielectric film. When fibre mirrors of reflectance of ~0.1% were produced, the insertion loss ranged from 0.055 to 0.3 dB and the average insertion loss was 0.15 dB.
Test Results for a High Temperature Non-Permanent-Magnet Traction Motor (2017)

Non-permanent-magnet machines are generally known to be less power dense than permanent magnet counterparts, but the absence of permanent magnets in these machines makes them well suited for high temperature applications. This offers a degree of freedom in improving their power density, because they can operate at higher electrical loading while maintaining acceptable efficiency. This paper presents a high temperature dc-biased reluctance machine that is structurally similar to a conventional switched reluctance machine. This non-permanent-magnet machine has a dc field winding and an ac three-phase armature winding. The machine is equipped with a high temperature 280 °C rated insulation system. Test results showing machine performance under continuous operation against the FreedomCar 2020 specifications as well as at high temperature up to 280 °C are presented. Compared with an initial design using conventional insulation designed for operation at 200 °C, the high temperature insulation system enabled the machine to operate at twice the temperature rise and achieve 43% increase in power.
ChemInform Abstract: MANNICH BASES OF FLUORENESPIROPYRROLIDINEDIONE (1980)

Abstract Das Spirofluorenderivat (I) reagiert mit Formaldehyd und sekundären Aminen (II) zu den Mannich‐Basen (III).
Application of Least-Squares Channel Estimation to Large-scale MU-MIMO-OFDM in the Presence of Terminal Mobility (2021)

This paper investigates the effect of multiplexing-based least squares (LS) channel estimation on uplink large-scale MU-MIMO-OFDM in the presence of terminal mobility. In uplink large-scale MU-MIMO, the same number of pilot symbols as that of mobile stations (MSs) is generally required, which results in the consumption of a substantial amount of resources for channel estimation. This overhead can be reduced by using the LS channel estimation in user multiplexing because this method has only to use a limited number of subcarriers, with a multipath length at most. In addition, the achieved overhead reductions can be effectively utilized for improving the tracking capability of channel estimation under varying channels. Since our performance evaluation focuses on mobile communications systems such as 6G, uplink large-scale MU-MIMO is assumed, and Gaussian belief propagation (GaBP) is applied to detect multiple uplink signals. The effectiveness of this method relative to that of the traditional LS method with the same number of pilot symbols is demonstrated under time selective fading through computer simulations.
The Light Bender Concept for Power Distribution on a Lunar Base (2021)

View Video Presentation: https://doi.org/10.2514/6.2021-4160.vid Power generation and distribution is a challenge for a future lunar base. A promising concept for lunar power distribution is the Light Bender—a system that utilizes autonomously deployed mirrors to reflect sunlight to shaded regions on the lunar surface. The Light Bender system consists of two components: tandem reflector mirrors (TRM) which reflect sunlight to a permanently shaded region and the Cassegrain Fresnel distribution optics (CFDO) which collects the reflected light from the TRM and redirects light to local consumer nodes. This paper describes the Light Bender system concepts and the associated system analysis and technology development performed as part of a 2021 NASA Innovative Advanced Concepts (NIAC) phase I award.
Correction: Tracking Single Cells in Live Animals Using a Photoconvertible Near-Infrared Cell Membrane Label (2013)

We describe a novel photoconversion technique to track individual cells in vivo using a commercial lipophilic membrane dye, DiR. We show that DiR exhibits a permanent fluorescence emission shift (photoconversion) after light exposure and does not reacquire the original color over time. Ratiometric imaging can be used to distinguish photoconverted from nonconverted cells with high sensitivity. Combining the use of this photoconvertible dye with intravital microscopy, we tracked the division of individual hematopoietic stem/progenitor cells within the calvarium bone marrow of live mice. We also studied the peripheral differentiation of individual T cells by tracking the gain or loss of FoxP3-GFP expression, a marker of the immune suppressive function of CD4 + T cells. With the near-infrared photoconvertible membrane dye, the entire visible spectral range is available for simultaneous use with other fluorescent proteins to monitor gene expression or to trace cell lineage commitment in vivo with high spatial and temporal resolution.
Electrical storms in Brugada syndrome: review of pharmacologic and ablative therapeutic options. (2005)

Electrical storm occurring in a patient with the Brugada syndrome is an exceptional but malignant and potentially lethal event. Efficient therapeutic solutions should be known and urgently applied because of the inability of usual antiarrhythmic means in preventing multiple recurrences of ventricular arrhythmias. Isoproterenol should be immediately infused while oral quinidine should be further administrated when isoproterenol is not effective. In case of failure of these therapeutic options, ablation of the triggering ventricular ectopies should be attempted.
Impact of Frequency Selectivity on the Information Rate Performance of CFO Impaired Single-Carrier Massive MU-MIMO Uplink (2016)

In this letter, we study the impact of frequency-selectivity on the gap between the required peruser transmit power in the residual carrier frequency offset (CFO) scenario i.e., after CFO estimation/compensation at the base-station (BS) and that in the ideal/zero CFO scenario, for a fixed per-user information rate, in single-carrier massive MU-MIMO uplink systems with the time-reversal maximum ratio combining receiver. Information theoretic analysis reveals that this gap decreases with increasing frequency-selectivity of the channel. Also, in the residual CFO scenario, an O(√M) array gain is still achievable (M is the number of BS antennas) in frequency-selective channels with imperfect channel estimates.
Continuous Gas‐Phase Hydroformylation of 1‐Butene using Supported Ionic Liquid Phase (SILP) Catalysts (2007)

Abstract The concept of supported ionic liquid phase (SILP) catalysis has been extended to 1‐butene hydroformylation. A rhodium‐sulfoxantphos complex was dissolved in [BMIM][ n ‐C 8 H 17 OSO 3 ] and this solution was highly dispersed on silica. Continuous gas‐phase experiments in a fixed‐bed reactor revealed these SILP catalysts to be highly active, selective and long‐term stable. Kinetic data have been acquired by variation of temperature, pressure, syngas composition, substrate and catalyst concentration. A linear dependency in rhodium concentration could be established over a large concentration range giving another excellent hint for truly homogeneous catalysis in the SILP system. Compared to former studies using propene, the SILP system showed significantly higher activity and selectivity with 1‐butene as feedstock. These findings could be elucidated by solubility measurements using a magnetic microbalance.
Dynamics of Replication-Independent Histone Turnover in Budding Yeast (2007)

Chromatin plays roles in processes governed by different time scales. To assay the dynamic behavior of chromatin in living cells, we used genomic tiling arrays to measure histone H3 turnover in G1-arrested Saccharomyces cerevisiae at single-nucleosome resolution over 4% of the genome, and at lower (approximately 265 base pair) resolution over the entire genome. We find that nucleosomes at promoters are replaced more rapidly than at coding regions and that replacement rates over coding regions correlate with polymerase density. In addition, rapid histone turnover is found at known chromatin boundary elements. These results suggest that rapid histone turnover serves to functionally separate chromatin domains and prevent spread of histone states.
Josephson readout electronics for the hybrid superconducting pixel detector (1998)

We have recently demonstrated the Hybrid Superconducting Pixel Detector (HSPD) principle using a test configuration. This demonstrator device consists of a semiconductive particle detector coupled to a Josephson Tunnel Junction (JTJ) acting as current sensitive discriminator. We used Minimum Ionising Particles (MIPs) as events generators. Experimental data show the first case of MIPs detection using JTJ. The efficiency of the demonstrator circuit reaches 90% with 2 MIPs and it will be improved once the complete device will be full integrated in one circuit. A second generation demonstrator, involving an eigth channel readout scheme fully implemented with superconducting electronics is being developed and will be discussed in some detail.
Study of the SP-100 radiator heat pipes response to external thermalexposure (1990)

This research presents the results of a study of the transient response of potassium heat pipes, simulating the SP-100 system radiator heat pipes, to external thermal exposure. Results demonstrate that a heat pipe failure caused by external thermal exposure below 200 kW/m2 is unlikely; however, a reverse operation that will transport a fraction of the external heat to the lithium in the secondary coolant loop will occur temporarily. This fraction of the external heat increases with the heat flux, the exposed fraction of the heat pipe, and the exposure time up to the heat pipe's response time (~ 6.5 s). Beyond this time, the fraction of the external heat transported to the secondary coolant becomes independent of the exposure time. Conversely, the fraction of the external heat radiated into space decreases as the exposed fraction of the heat pipe and/or the heat flux increases. Results also demonstrate that a full external exposure as low as 17 kW/m2 lasting for more than 6.5 s can reverse the operation of the radiator's heat pipes, regardless of their lengths. However, a full exposure of the radiator at its inward surface to a net heat flux of only 200 kW/m2 for more than 6.5 s could cause the heat pipe wall to fail as the induced stress in the wall due to the vapor pressure of the potassium working fluid exceeds the yield strength of the titanium liner of the wall.
A Constant Frequency Based Torque Ripple Free Three level NPC Brushless Motor Drive (2023)

The Brushless DC motor with trapezoidal back EMF enables them to be smaller, lighter, and more robust in design. Multilevel inverter-based drives have become crucial for medium and high-power applications of Brushless DC motor drives. However, a Brushless DC(BLDC) motor suffers from the severe drawback of commutation torque ripples, mainly due to the inductive nature of the stator. Nevertheless, with a three-level inverter to a BLDC motor, a significant torque ripple reduction can be observed compared to a conventional two-level BLDC drive. In addition, the good dynamic performance of hysteresis controllers makes them reliable for the current control. However, the major demerit is that it gives a variable switching frequency and asymmetrical switching pulses, which could amplify the torque ripples. An interleaving constant switching frequency-based current controller is proposed in this work, which divides the error into multiple bands. The error is compared to an interleaving carrier frequency-based comparator to produce the switching signal for the given reference torque. The proposed controller remarkably improves the performance of the BLOC drive in the low-speed region, and a significant reduction in torque ripple is obtained. The proposed method is implemented on the MATLAB Simulink platform, and the effectiveness is validated by the results presented.