gebhart/patrepeval huggingface dataset:
A 23&#x2013;35 GHz MEMS tunable all-silicon cavity filter with stability characterization up to 140 million cycles (2014)

A connectorized RF MEMS tunable two-pole band-pass filter is demonstrated as the first all-silicon evanescent mode cavity filter operating in the K-Ka band. All filter components are fabricated with cost-effective silicon micromachining techniques. The filter's poles are controlled by two micro-corrugated MEMS diaphragms that are engineered to be independently controlled with voltages below 140 V. Advanced fabrication techniques are applied for the first time to ensure independent pole-frequency control with no additional filter loss and improved fabrication accuracy and stability. The filter's measured tuning range is from 23 GHz to 35 GHz (0–140 V) with fractional bandwidth ranging from 0.8% to 4%. The filter's measured loss varies from 4.2 to 1.5 dB including its connectors. The extracted filter quality factor varies from 530 to 750. The maximum actuation voltage of 140 V is 2× lower than previous demonstrations for similar tuning ranges. The filter's stability has been tested up to 140 million cycles (0–70 V cycling) with no failures observed. The filter exhibits a burn-in period of about 40 million cycles. The filter provides a stable behavior after the initial burn-in period.
A cost-effective packaging for the environmental hardening of passive optical devices (2004)

A low cost packaging method, based on aluminium layered laminate sealing technology, is presented in this paper for the environmental hardening of planar waveguide splitters, filter WDM assemblies and other non-robust passive devices. Since the former two passive components will play a prominent role in PON networks and their upgrading scenarios, we questioned their long term reliability in uncontrolled outside plant environments by investigating their behavior in environmental testing as defined by Telcordia 1221. In particular, the optical performance of planar splitters and filter WDM assemblies from randomly chosen suppliers was monitored during temperature cycling and long term damp heat testing. A comparison was made between devices as packaged by the supplier and devices packaged in our Al laminate packaging. Although the packaging of planar waveguides has improved over the last years, our study convincingly demonstrates failure modes in the non-laminate packaged planar splitters. In addition, dramatic failures were also observed in filter WDM's assembled in modules for wide WDM, coarse WDM and dense WDM, which raise serious concerns about their long term environmental reliability. The laminate packaged devices however all pass the severe test conditions, exhibiting a better stability. This favors the use of our packaging method for the integration of planar splitters and filter WDM based assemblies in outside plant network elements.
pFARs, Plasmids free of antibiotic resistance markers, display high‐level transgene expression in muscle, skin and tumour cells (2010)

Thus, we have designed a novel strategy for the efficient production of biosafe plasmids and demonstrated their potentiality for nonviral gene delivery and high-level transgene expression in several tissues.
Total syntheses of derivatives of protoporphyrin IX regioselectively labeled with carbon-13 in the methyls (1986)

Total syntheses, from monopyrroles via tripyrrenes and a,c-biladienes, of the four isomers 2–5 of protoporphyrin IX dimethyl ester in which the 1-, 3-, 5-, and 8-methyl groups are individually and regioselectively enriched with carbon-13 are described. The source of labeled carbon was 90% carbon-13-enriched paraformaldehyde, and methyls were inserted at the monopyrrole stage by reductive C-alkylation. The carbon-13-labeled porphyrins, as the corresponding hemes, are of interest as probes in carbon-13 NMR spectroscopic studies of reconstituted heme proteins. © 1986, American Chemical Society. All rights reserved.
Supplementary Figure 6 from <i>De novo</i> Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation (2023)

Supplementary Figure 6 from &lt;i&gt;De novo&lt;/i&gt; Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
Enabling Bring-Your-Own-Device using mobile application instrumentation (2013)

Many enterprises are investigating Bring-Your-Own-Device (BYOD) policies, which allow employees to use their personal devices in the workplace. This has led to mixed-use scenarios, where consumer and enterprise software are installed on the same device. In this paper, we describe the Secured Application Framework for Enterprise (SAFE), a comprehensive system for enabling BYOD that allows enterprise and consumer applications to coexist side-by-side on the device. Rather than partition the device by profiles, SAFE embeds enterprise functions in each enterprise application; this allows for a seamless user experience and minimal intrusiveness on the part of the enterprise. We describe the SAFE toolset that implements the embedding of the SAFE instrumentation layer, and then provide an overview of several enterprise features that can be configured using SAFE. Specifically, we describe modeling for analytics, testing and replay, anomaly detection, and cloud data services, all enterprise features that can transparently be added to mobile applications.
Cationic polymerizations of 3‐methylbutene‐1. II. Polymerizations at extremely low temperatures (1964)

Abstract The cationic polymerization of 3‐methylbutene‐1 has been studied at extremely low temperatures e.g., −130°C. and below. Practically no polymerization occurs, even at high catalyst concentrations, and the system lies “dormant” at −150°C. The molecular weight‐conversion curve obtained with AlCl 3 is a straight line which can be extrapolated through the origin. The slope of this line is determined by monomer concentrations. Higher molecular weights are obtained at the same conversion with higher monomer concentrations. With boron trifluoride catalyst, the linear part of the curve does not extrapolate back through the origin. Product molecular weights were higher in ethyl chloride than in pentene with BF 3 at the same conversion level at −130°C.
Capsaicin, a TRPV1 Ligand, Suppresses Bone Resorption by Inhibiting the Prostaglandin E Production of Osteoblasts, and Attenuates the Inflammatory Bone Loss Induced by Lipopolysaccharide (2012)

Capsaicin, a transient receptor potential vanilloid type 1 (TRPV1) ligand, regulates nerve-related pain-sensitive signals, inflammation, and cancer growth. Capsaicin suppresses interleukin-1-induced osteoclast differentiation, but its roles in bone tissues and bone diseases are not known. This study examined the effects of capsaicin on inflammatory bone resorption and prostaglandin E (PGE) production induced by lipopolysaccharide (LPS) in vitro and on bone mass in LPS-treated mice in vivo. Capsaicin suppressed osteoclast formation, bone resorption, and PGE production induced by LPS in vitro. Capsaicin suppressed the expression of cyclooxygenase-2 (COX-2) and membrane-bound PGE synthase-1 (mPGES-1) mRNAs and PGE production induced by LPS in osteoblasts. Capsaicin may suppress PGE production by inhibiting the expression of COX-2 and mPGES-1 in osteoblasts and LPS-induced bone resorption by TRPV1 signals because osteoblasts express TRPV1. LPS treatment markedly induced bone loss in the femur in mice, and capsaicin significantly restored the inflammatory bone loss induced by LPS in mice. TRPV1 ligands like capsaicin may therefore be potentially useful as clinical drugs targeting bone diseases associated with inflammatory bone resorption.
Effectiveness of a publicly funded clinical paediatric weight management program on obesity outcomes (2015)

This paediatric weight management program effectively reduced the prevalence of obesity. Patients who had longer treatment times experienced greater reductions in obesity. Overall, the present study highlights that long-term patient attendance may be needed to better support paediatric weight management patients.
Low Pressure Thermal Decomposition Studies Selected Nitramine and Dinitramine Energetic Materials (1992)

Abstract : SRI International conducted a study of the thermal decomposition of a newly developed energetic material ammonium dinitramide (ADN), as well as, for comparison, two related materials ammonium nitrate (AN), and nitramide (NH2HO2). Brief studies were also performed with RDX and with AgN(NO2)CH2CN, which was tested as a potential source of the suspected RDX intermediate CH2=NNO2. The former portion of the work has resulted in a manuscript, which is being submitted for publication and is included as an appendix to this final report. A summary of the work and its principal findings is given below, beginning with the results for ADN itself. Pyrolysis of ADN under low pressure showed acid-base dissociation like AN, but it also resulted in some decomposition to N2O, NO, and water. The onset of evolution of these species was at 90 C, and as in the case of AN, an 'explosive' event was noted at 174 C, which is about 80 C higher than the melting point of ADN and 15 C higher than thermal decomposition in a DSC.
Calculation of the Elastic Demand Curve for a Day-Ahead Secondary Reserve Market (2009)

The level of secondary reserve needed in a power system is traditionally settled by system operators according to engineering criteria. This paper proposes a novel methodology to determine the optimum level of secondary reserve based on both engineering and economic criteria. Within the proposed approach a price elastic-quantity demand curve for the secondary reserve is built. This approach assumes that the provision of secondary reserve is made under a competitive market. In this market, the supply curve that collects the bids from generators providing secondary reserve is matched with the calculated elastic demand cost curve. The cross of the supply and demand curves determines the optimal level of secondary reserve and the price for provision of the service. The developed approach is illustrated with a case study based on the current day-ahead secondary reserve market in Spain.
Science and Technology Centers and Education (2002)

Jeffrey Mervis's description of the science and technology center (STC) program supported by the National Science Foundation (NSF) (“Science with an agenda: NSF expands centers program,” News Focus, 26 July, p. [506][1]) presents a view of the program that is not universally shared by all of the
Visible‐Light Photocatalytic Conversion of Carbon Monoxide to Methane by Nickel(II) Oxide (2013)

Solare Brennstoffe: Verschiedene n- und p-Halbleiter wurden für die Herstellung nachhaltiger solarer Brennstoffe getestet. p-Halbleiter wie NiO, Fe3O4, Co3O4 und CuO können Kohlenmonoxid mit Wasser oder Wasserstoff zu Methan reduzieren (siehe Bild). Die höchste Methanausbeute lag bei 17.26 mmol Methan pro Katalysatorgramm und wurde mit einem NiO-Katalysator und überschüssigem Wasserstoff erhalten. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
<title>SSUSI - Horizon-to-horizon and limb-viewing spectrographic imager for remote sensing of environmental parameters</title> (1993)

We review some of the features of the Special Sensor Ultraviolet Spectrographic Imager (SSUSI) and describe the environmental parameters that will be produced on an operational basis from this instrument's data. The associated algorithms are summarized. SSUSI consists of a scanning imaging spectrograph (SIS) whose field-of-view is scanned from horizon to horizon and a nadir-looking photometer system (NPS). The SIS produces simultaneous monochromatic images at five 'colors' in the spectral range 115nm to 180nm. The NPS consists of three photometers with filters designed to monitor the airglow at 427.8nm and 630nm and the terrestrial albedo near 630nm. SSUSI will fly on the DMSP Block 5D3 satellites S-16 through S-19. In a companion paper we provide more details on the Special Sensor Ultraviolet Spectrographic Imager (SSUSI).
Uptake of dibucaine into large unilamellar vesicles in response to a membrane potential. (1985)

Local amine anesthetics appear to exert their effects in the charged (protonated) form on the cytoplasmic side of excitable membranes. Two features of interest are the mechanism whereby these drugs move across the membrane to the inner monolayer and the actual membrane concentrations achieved. In this work, we have investigated the influence of a K+ diffusion potential, delta psi, on the transmembrane distribution and concentration of the local anesthetic dibucaine employing large unilamellar vesicle systems. It is demonstrated that egg phosphatidylcholine large unilamellar vesicles exhibiting a delta psi (interior negative) actively accumulate dibucaine to achieve high interior concentrations. 31P and 13C nuclear magnetic resonance studies show that the internalized drug is localized to the vesicle inner monolayer, and suggest that the protonated form of the anesthetic is the species that is actively transported. The inner monolayer anesthetic concentrations thus achieved can be an order of magnitude or more larger than predicted on the basis of anesthetic lipid-water partition coefficients. It is suggested that these effects may be related to the mechanisms whereby local anesthetics are localized and concentrated at their sites of action in nerve membranes.
Managing Drilling Risk and Uncertainty Standard in Well Placement (2009)

Abstract An effective anticollision risk management approach is essential for drilling safely in the congested subsurface environments increasingly common in today's drilling programs. Because there is as yet no industry-wide standard for collision risk assessment and management, many companies have developed their own standards, which can differ in significant details. In one recent project, both the operator and the directional drilling contractor had developed specific anticollision procedures. The challenge was to create a drilling program that satisfied the requirements of both standards. This paper describes the problems we encountered and the solutions we created to successfully design and execute a drilling plan satisfactory to both companies.
Force-controlled lifting of molecular wires (2011)

Lifting a single molecular wire off the surface with a combined frequency-modulated atomic force and tunneling microscope it is possible to monitor the evolution of both the wire configuration and the contacts simultaneously with the transport conductance experiment. In particular, critical points where individual bonds to the surface are broken and instabilities where the wire is prone to change its contact configuration can be identified in the force gradient and dissipation responses of the junction. This additional mechanical information can be used to unambiguously determine the conductance of a true molecular wire, that is, of a molecule that is contacted via a pointlike ``crocodile clip'' to each of the electrodes but is otherwise free.
Guardrail Run-Out Length Design Procedures Revisited (2006)

Encroachment data sets by Hutchinson and Kennedy and by Cooper, which are used as the foundation for current guardrail design procedures, are compared with each other and with crash databases. Discrepancies between the two data sets are examined and explained. These encroachment data sets are also compared to available real-world crash data, including new crash data from an ongoing study. The encroachment and crash data evaluations clearly indicate that guardrail length calculation procedures developed from the Cooper encroachment data provide more appropriate guardrail run-out length designs for minimizing injuries and fatalities associated with ran-off-road crashes.
운동역학 : 테니스 스핀 서브동작시 관절운동의 분석 (1998)

본 연구는 테니스 스핀 서브동작시 어깨관절을 중심으로 한 3차원 다축운동과 분절간의 상대각운동 특성을 파악하는데 목적을 두었다. 이와 같은 목적을 달성하기 위하여 국가대표 테니스선수 7명을 대상으로 어깨관절과 상지관절에 지역축을 심고 Euler`s Angles를 이용하여 분절의 상대각을 계산하고 운동학적 변인들을 계산한 결과 다음과 같은 결론을 얻었다. 임팩트 직전에 진행방향으로의 속도를 빠르게 하여 소요시간을 단축하므로서 정확하고 강한 스핀동작을 구사하는 훈련이 우선되어야 한다. 스핀 서브에서 임팩트시 라켓의 선형속도에 영향을 미치는 요인은 손목의 외전, 팔꿈치의 신전, 어깨관절의 내측회전 순으로 속도가 빠르게 나타났다. 분절저지점의 최대 선형속도는 어깨관절, 팔꿈치 관절, 손목관절, 라켓헤드 순서대로 나타났다. 이것은 분절운동의 원리대로 동작이 일어나는 것을 의미하는 것으로 테니스 서브의 특성으로 중요하다.
Gal-Gal Binding and Hemolysin Phenotypes and Genotypes Associated with UropathogenicEscherichia coli (1985)

To determine whether uropathogenic strains of Escherichia coli exhibit a distinctive constellation of phenotypes, we examined 44 urinary isolates from women with radiologically normal urinary tracts and pyelonephritis, cystitis, or asymptomatic bacteriuria and 73 fecal isolates from healthy control subjects. The strains were characterized by their O serogroup, by their binding specificity (as determined by adhesins), and by their production of hemolysin and colicin V. In addition, the strains were assessed for homologous gene sequences by means of DNA-hybridization probes prepared from cistrons that encode hemolysin and the Gal-Gal binding adhesin--two determinants of virulence, which cause tissue injury and promote bacterial colonization of uroepithelia, respectively. In contrast to most isolates from normal feces and from the urine of patients with asymptomatic bacteriuria, pyelonephritis strains belong to a small number of O serogroups; all express the Gal--Gal binding adhesin and 75 per cent are hemolytic. A gene probe for the Gal--Gal binding adhesin, derived from the chromosome of one strain from a patient with pyelonephritis, hybridized with the DNA of all other pyelonephritis strains. The probe for the hemolysin gene hybridized with DNA from all other hemolytic strains. These data indicate that most cases of pyelonephritis are due to a small number of pathogenic clones that express critical determinants of virulence, and that the nucleotide sequences for hemolysin and the Gal--Gal binding adhesin in heterologous strains share homology. We are tempted to speculate that the gene products of these shared regions of the genome might form the basis for a vaccine against pyelonephritis.
Microsecond Timescale Surface Temperature Measurements in Micro Pulsed Plasma Thrusters (2003)

A time-resolved surface temperature diagnostic for ablation-controlled arcs is in development at the Air Force Research Laboratory at Edwards AFB. The diagnostic draws on heritage from the experimental dynamic crack propagation community which has used photovoltaic infrared detectors to measure temperature rise in materials in the process of fracture. The microsecond time-scales involved in the fracture process suggest that such detectors may be applicable to the ablation-controlled discharges in pulsed plasma thrusters as a direct measurement of surface temperature during and after the arc. HgCdTe detectors are evaluated for use on the surface of an AFRL micro-pulsed plasma thruster. Evaluation of the diagnostic focuses on development of valid calibration methodology and application of the detector in the presence of a plasma. Current calibration techniques are reviewed with physical limitations discussed. An estimate for the wavelength dependent emissivity of Teflon is determined and measurements are performed in real-time on the surface of a thruster. Teflon vapor pressure is calculated for post-pulse temperature measurements.
PCR detection ofBrachyspira aalborgiandBrachyspira pilosicoliin human faeces (2001)

Previously-developed PCR protocols specific for the 16S rRNA gene of the intestinal spirochaetes Brachyspira aalborgi and Brachyspira pilosicoli were adapted for the detection of these species in human faeces, following DNA extraction and purification using mini-prep columns. The limits of detection in seeded faeces for B. aalborgi and B. pilosicoli respectively were 2x10(2) and 7x10(3) cells per PCR reaction, equivalent to 5x10(4) and 1x10(5) cells per g of faeces. The PCR techniques were applied to faecal samples from two patients with histological evidence of intestinal spirochaetosis. In the first patient, in whom B. aalborgi had been identified by 16S rDNA PCR from colonic biopsies, a positive amplification for B. aalborgi only was obtained from the faeces. The organism could not be isolated from these faeces. In the second patient, both colonic biopsies and faeces were PCR positive for B. pilosicoli only, and B. pilosicoli was isolated from the faeces. These new faecal PCR protocols should be valuable for future studies on the epidemiology of intestinal spirochaete infections in human populations, particularly as it is not currently possible to isolate B. aalborgi from faeces.
Foot-pulse radiation drive necessary for ICF ignition capsule demonstrated on Z generator (2003)

Summary form only given. Implosion and ignition of an indirectly-driven ICF capsule operating near a Fermi-degenerate isentrope requires initial Planckian-radiation-drive temperatures of 70-to-90 eV to be present for a duration of 10-to-15 ns prior to the main drive pulse. Such capsules are being designed for high pulsed-power generators such as X1. This foot-pulse drive capability has been recently demonstrated in a NIF-sized (/spl phi/=6-mm 1=7-mm), gold hohlraum, using a one-sided static-wall hohlraum geometry on the Z generator. The general arrangement utilized nested tungsten-wire arrays of radii (mass) 20 mm (2 mg) and 10 mm (1 mg) that had an axial length of -10 mm. The arrays were driven by a peak current of -21 MA and were made to implode on a 2-/spl mu/m-thick Cu annulus (mass=4.5 mg), which had a radius of 4 mm and was filled with a low-density CH foam, all centered about the z-axis. The gold hohlraum was mounted on axis and above the Cu/foam target. A 2.9-mm-radius axial hole between the top of the target and hohlraum permitted the X-rays generated from the implosion to enter the hohlraum. The radiation within the hohlraum was monitored by viewing the hohlraum through a 3-mm diameter hole on the lateral side of the hohlraum with a suite of diagnostics. The radiation entering the hohlraum was estimated by an additional suite of on-axis diagnostics, in a limited number of separate shots, when the hohlraum was not present. Additionally, the radiation generated outside the Cu annulus was monitored, for all shots, through a 3-mm diameter aperture located on the outside of the current return can.