gebhart/patrepeval huggingface dataset:
Sonochemical Synthesis of Nanocrystalline Rare Earth Orthoferrites Using Fe(CO)5 Precursor (2004)

This paper describes, for the first time, a simple sonochemical method for the synthesis of nanoparticles of a series of rare earth orthoferrites. This sonochemical process is enabling synthesis of nanoparticles of the rare earth orthoferrites at a substantially lower calcination temperature by using simple precursors, iron pentacarbonyl and rare earth carbonates. It is particularly noteworthy that the cogeneration of the garnet phase has not been observed, as is usual with the conventional methods. The drastic reduction in the calcination temperature could be due to the ultrasonic generation of amorphous iron oxide from Fe(CO)5. Nanosized GdFeO3, ErFeO3, TbFeO3, and EuFeO3 were prepared by this method and their magnetic properties were also studied in detail.
ChemInform Abstract: Total Synthesis of Spirastrellolide F Methyl Ester. Part 1. Strategic Considerations and Revised Approach to the Southern Hemisphere. (2010)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Synthesis of 2‐Butanol by Selective Hydrogenolysis of 1,4‐Anhydroerythritol over Molybdenum Oxide‐Modified Rhodium‐Supported Silica (2016)

Rh-MoOx /SiO2 (Mo/Rh=0.13) is an effective catalyst for the hydrogenolysis of 1,4-anhydroerythritol (1,4-AHERY) and provides 2-BuOH in high yield of 51 %. This is the first report of the production of 2-BuOH from 1,4-AHERY by hydrogenolysis. 1,4-AHERY was more suitable as a starting material than erythritol because the 2-BuOH yield from erythritol was low (34 %). Based on the kinetics and comparison of reactivities of the related compounds using Rh-MoOx /SiO2 and Rh/SiO2 catalysts, the modification of Rh/SiO2 with MoOx leads to the high activity and high selectivity to 2-BuOH because of the generation of reactive hydride species and the strong adsorption of 1,4-AHERY on MoOx species. The reaction proceeds by main two routes, (I) the combination of single C-O hydrogenolysis with the desorption of intermediates, a usual route in hydrogenolysis, and (II) multiple C-O hydrogenolysis without the desorption of intermediates from the active site, and the reaction mechanism for Route (II) is proposed.
Local Structure and Electronic State of Atomically Dispersed Pt Supported on Nanosized CeO2 (2019)

Single atom catalysts (SACs) have shown high activity and selectivity in a growing number of chemical reactions. Many efforts aimed at unveiling the structure–property relationships underpinning these activities and developing synthesis methods for obtaining SACs with the desired structures are hindered by the paucity of experimental methods capable of probing the attributes of local structure, electronic properties, and interaction with support—features that comprise key descriptors of their activity. In this work, we describe a combination of experimental and theoretical approaches that include photon and electron spectroscopy, scattering, and imaging methods, linked by density functional theory calculations, for providing detailed and comprehensive information on the atomic structure and electronic properties of SACs. This characterization toolbox is demonstrated here using a model single atom Pt/CeO2 catalyst prepared via a sol–gel-based synthesis method. Isolated Pt atoms together with extra oxygen atoms passivate the (100) surface of nanosized ceria. A detailed picture of the local structure of Pt nearest environment emerges from this work involving the bonding of isolated Pt2+ ions at the hollow sites of perturbed (100) surface planes of the CeO2 support, as well as a substantial (and heretofore unrecognized) strain within the CeO2 lattice in the immediate vicinity of the Pt centers. The detailed information on structural attributes provided by our approach is the key for understanding and improving the properties of SACs.
Supplementary Tables 1-14 from Genetic Alterations in the Tyrosine Kinase Transcriptome of Human Cancer Cell Lines (2023)

Supplementary Tables 1-14 from Genetic Alterations in the Tyrosine Kinase Transcriptome of Human Cancer Cell Lines
Positive impact of autophagy in human breast cancer cells on local immunosurveillance (2016)

In human breast cancer cells, the presence of cytoplasmic dots positive for microtubule-associated proteins 1A/1B light chain 3B (LC3B) indicates enhanced autophagic flux and favorable prognosis. LC3B(+) puncta within malignant cells positively correlate with the intratumoral abundance of CD8(+) cytotoxic T lymphocytes, yet negatively correlate with the frequency of local FOXP3(+) regulatory T cells and CD68(+) tumor-associated macrophages, resulting in an improvement of CD8(+)/FOXP(+) or CD8(+)/CD68(+) ratios.
Geometrical optics and blackbody radiation (2007)

Contrary to the customary way, some of the geometrical optics principles in free-space and two dimensions is deduced from blackbody radiation transfer. This is obtained from three hypotheses: (1) a blackbody radiates power proportional to its perimeter, and a convex blackbody does not radiate to itself, (2) reciprocity in radiation transfer, and (3) energy conservation. The analysis of an abstract relay element will lead to deduction of the reflection law in an unconventional form and new properties of the elliptical mirror as an ideal radiation transfer device.
DATA - Differential Address Trace Analysis: Finding Address-based Side-Channels in Binaries (2018)

Cryptographic implementations are a valuable target for address-based side-channel attacks and should, thus, be protected against them. Countermeasures, however, are often incorrectly deployed or completely omitted in practice. Moreover, existing tools that identify information leaks in programs either suffer from imprecise abstraction or only cover a subset of possible leaks. We systematically address these limitations and propose a new methodology to test software for information leaks. In this work, we present DATA, a differential address trace analysis framework that detects address-based side-channel leaks in program binaries. This accounts for attacks exploiting caches, DRAM, branch prediction, controlled channels, and likewise. DATA works in three phases. First, the program under test is executed to record several address traces. These traces are analyzed using a novel algorithm that dynamically re-aligns traces to increase detection accuracy. Second, a generic leakage test filters differences caused by statistically independent program behavior, e.g., randomization, and reveals true information leaks. The third phase classifies these leaks according to the information that can be obtained from them. This provides further insight to security analysts about the risk they pose in practice. We use DATA to analyze OpenSSL and PyCrypto in a fully automated way. Among several expected leaks in symmetric ciphers, DATA also reveals known and previously unknown leaks in asymmetric primitives (RSA, DSA, ECDSA), and DATA identifies erroneous bug fixes of supposedly fixed constant-time vulnerabilities.
Biochemical and Structural Characterization of the Tautomycetin Thioesterase: Analysis of a Stereoselective Polyketide Hydrolase (2010)

A narrow tunnel: Biochemical and structural analysis of the tautomycetin thioesterase (TE) has provided the first high-resolution structure of a linear-chain-terminating TE in polyketide biosynthesis, showing the enzyme to be stereoselective with a constrained substrate chamber relative to macrolactone-forming thioesterases. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Mathematical spatio-temporal model of drug delivery from low temperature sensitive liposomes during radiofrequency tumour ablation (2010)

Combination of LTSL-DOX with thermal ablation allows localised drug delivery with higher tumour tissue concentrations than conventional chemotherapy. Our model may facilitate drug delivery optimisation via investigation of the interplays among liposome properties, tumour perfusion, and heating regimen.
Pharmacology of Dichloromethotrexate (1989)

Journal Article Pharmacology of Dichloromethotrexate Get access JOSEPH R. BERTINO JOSEPH R. BERTINO Developmental Therapy and Clinical Investigation Sloan-Kettering Institute1274 York Ave. New York N.Y. 10021 Search for other works by this author on: Oxford Academic PubMed Google Scholar JNCI: Journal of the National Cancer Institute, Volume 81, Issue 10, 22 May 1989, Page 815, https://doi.org/10.1093/jnci/81.10.815 Published: 22 May 1989
Applying big data analytics to support Kansei engineering for hotel service development (2019)

Purpose Leisure and tourism activities have proliferated and become important parts of modern life, and the hotel industry plays a necessary role in the supply for and demand from consumers. The purpose of this paper is to develop guidelines for hotel service development by applying a service development approach integrating Kansei engineering and text mining. Design/methodology/approach The online reviews represent the voice of customers regarding the products and services. Consumers’ online comments might become a key factor for consumers choosing hotels when planning their tourism itinerary. With the framework of Kansei engineering, this paper adopts text mining to extract the sets of Kansei words and hotel service characteristics from the online contents as well as the relationships among Kansei words, service characteristics and these two sets. The relationships are generated by using link analysis, and then the guidelines for hotel service development are proposed based on the obtained relationships. Findings The results of the present research can provide the hotel industry a comprehensive understanding of hotels’ customers opinions, and can offer specific advice on how to differentiate one’s products and services from competitors’ in order to improve customer satisfaction and increase hotels’ performance in the end. Finally, this study finds out the service development guidelines to meet customers’ requirements which can provide suggestions for hotel managers. The implications both for academic and industry are also drawn based on the obtained results. Originality/value Now, in the internet era, consumers can comment on their hotel living experience directly through the internet. The large amount of user-generated content (UGC) provided by consumers also provides chances for the hospitality industry to understand consumers’ opinions through online review mining. The UGC with consumers’ opinions to hotel services can be continuously collected and analyzed by hoteliers. Therefore, this paper demonstrates how to apply the hybrid approach integrating Kansei engineering and online review mining to hotel service development.
The Treatment of Unstable Angina Pectoris(UAP) with Low Molecular Weight Heparin(LMWH) and Aspirin (2002)

Objective:To observe?compare and evalute the efficiency and safety of low molecular weight heparin(LMWH)and Aspirin in the treatment of unstable angina pectoris(UAP).Methods:60 cases were classified randomly into two groups:In the curing group,500IU LMWH In the comparative group,the patients were given Aspirin 100mg daily,the other therapies were the same in both groups.Results:The effective rate of the curing group was 96.6%,the comparative one was 67%,respectively,There were significant difference between two groups( P 0.05 ).Conclusion:The LMWH and Aspirin have more advantage of safety and efficiency than simple Aspirin in the treatment of UAP.
Cognitive load-control for congested Wireless Sensor Network channels (2013)

Modern wireless sensors are capable of analyzing measured data and transmit at high rates if needed. They may individually or collectively select how much data shall be sent depending on predefined rules tied to properties of measured data. Sending rates thereby change triggered by events appearing in the sensor environment. With wireless technologies such as 802.15.4 (ZigBee) having limited capacity uncontrolled traffic can easily cause overload resulting in a decreased throughput. This paper presents a load control mechanism that uses multiple inputs, demand for transmission capacity and perceived quality at each sensor node, to properly configure sending rates of these nodes. The mechanism is based on Fuzzy Logic and quality assessed with utility functions for packet loss and throughput. NS-3 simulation results show clear improvements in overall throughput at high loads when the proposed mechanism is enabled.
A Flexible and Non-intrusive Approach for Computing Complex Structural Coverage Metrics (2015)

Software analysis tools and techniques often leverage structural code coverage information to reason about the dynamic behavior of software. Existing techniques instrument the code with the required structural obligations and then monitor the execution of the compiled code to report coverage. Instrumentation based approaches often incur considerable runtime overhead for complex structural coverage metrics such as Modified Condition/Decision (MC/DC). Code instrumentation, in general, has to be approached with great care to ensure it does not modify the behavior of the original code. Furthermore, instrumented code cannot be used in conjunction with other analyses that reason about the structure and semantics of the code under test. In this work, we introduce a non-intrusive preprocessing approach for computing structural coverage information. It uses a static partial evaluation of the decisions in the source code and a source-to-bytecode mapping to generate the information necessary to efficiently track structural coverage metrics during execution. Our technique is flexible; the results of the preprocessing can be used by a variety of coverage-driven software analysis tasks, including automated analyses that are not possible for instrumented code. Experimental results in the context of symbolic execution show the efficiency and flexibility of our non- intrusive approach for computing code coverage information.
Registration of TN13‐4304 soybean germplasm with good yield, high meal protein, and resistance to peanut and southern root knot nematode (2022)

Abstract TN13‐4304 (Reg. no. GP‐450, PI 699660) is a conventional late maturity group (MG) IV (relative maturity 4.9) soybean [ Glycine max (L.) Merr.] with high seed yield potential, high meal protein, and resistance to southern root knot nematode, peanut root knot nematode, and stem canker. It was developed and released by the University of Tennessee soybean breeding program. TN13‐4304 was developed from reselection within the Asian Vegetable Development Center cultivar ‘AGS 292’, which was originally released for use in the edamame market. In replicated field trials across 26 environments of the USDA Southern Soybean Preliminary MG V Early and Uniform MG V Tests, TN13‐4304 yielded 108 and 101%, respectively, of the average yield of the commercial checks. In the 2018 United Soybean Board Southern Diversity Yield Trials MG IV Late (USBDIV4L), tested across three states, TN13‐4304 yielded 115% of the average of three Asgrow commercial cultivars and had an average seed protein content and oil content of 429 and 219 g kg –1 , respectively. In the same test the three Asgrow cultivars had an average seed protein content of 403 g kg –1 and an average oil content of 225 g kg –1 , reported using a near infrared spectrometer. In the USBDIV4L, TN13‐4304 was one of only two genotypes that met all targets of yield, seed protein, oil, and meal protein in the test. TN13‐4304 has white flowers, gray pubescence, and a determinate growth habit. The pods have a tan pod wall and the seeds are yellow with smooth seed coats. For decades soybean genetic improvement has focused on increasing yield, which typically increased seed oil content at the expense of protein content in the meal. Although yield remains the top priority, improvements to seed composition have become very important and can have a significant impact on value. There is a limited supply of conventional (non‐genetically modified) germplasm lines available for soybean breeders. Typically, these are released by public land grant universities and by the USDA‐ARS. Release of soybean line TN13‐4304 would provide a conventional line with high protein meal and disease resistance that is useful for breeding programs.
(chromatin/development/regeneration) (2016)

The tissue and cellular distribution and regula- tion of the chromatin protein HI* has been examined in developing and adult mouse and in rat. The protein appears in specific cell types of solid tissues only when the cells have terminated their maturation. This was found for brain, retina, striated and cardiac muscle, and liver. In tissues that depend on hormones for their function and maintenance, the expression of HI? is dependent on the continued presence of the specific maintenance hormone. In regenerating rat liver the amount of HI? decreases to one-third after the onset of DNA synthesis. The possible role of HI? is dis- cussed in light of these results. Proteins with properties similar or identical to those of the very lysine rich chromosomal protein H1? have been described in several mammalian tissues and in tissue culture cells (1-16). The protein isolated from ox or mouse liver has been shown to con- sist of two subfractions that have identical molecular weights (25,000) but differ slightly in charge (2, 3). The two subfractions appear to have similar or identical amino acid compositions and peptide patterns. Recently it has been shown that H1? has ex- tensive sequence homology with histone H5 from goose eryth- rocytes (4). H1? is of interest for several reasons. Its level in different tissues varies widely and it is predominantly found in tissues exhibiting little cellular proliferation (1, 6, 7, 9, 15, 17). In ear- lier work, using indirect immunofluorescence with monospe- cific antibodies, we showed that H1? was present in many but not all fully mature postmitotic cells, and therefore that its dis- tribution in different cells of the adult mouse is heterogeneous (15). These data suggest that H1? may play an important role in cell regulation. The concept that H1? is involved in developmental regulation is strengthened by the observations that in rat pancreas, liver, and spleen the protein appears after birth once cell proliferation in the organs has ceased (7, 8, 17). It has also been shown to decrease in regenerating rat pancreas and liver (5, 18). We report here studies on the regulation of H1? in devel- oping mouse and in adult mouse and rat. The presence of H1? was shown to be correlated with cell maturation during devel- opment and liver regeneration. It was also found to be hor- monally regulated in several glands in the adult. The results suggest that H1? may play a role in the maintenance of the
Cerebrospinal fluid protein patterns in neurodegenerative disease revealed by liquid chromatography‐Fourier transform ion cyclotron resonance mass spectrometry (2004)

This study demonstrates the power of a novel proteomic approach developed for the detection and identification of biological markers in body fluids. The goal was to observe alterations in the protein patterns of cerebrospinal fluid (CSF) related to amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder with unknown etiology. In the experiments, tryptic digests of CSF from patients and healthy controls were analyzed by on-line capillary liquid chromatography-Fourier transform ion cyclotron resonance mass spectrometry. (FT-ICR MS) Typically, around 4000 peptides were detected in one such experiment, and a pattern recognition program was constructed for the data analysis to distinguish mass chromatograms from patients and controls. This strategy was evaluated comparing the peptide patterns of CSF spiked in vitro with a biomarker, with control CSF. The patterns were clearly separated and the tryptic peptides of the biomarker were successfully selected as characteristic peaks. Hence, the method was applied to compare mass chromatograms of CSF from 12 ALS-patients and 10 matched healthy controls. While no biomarker alone could be identified from the characteristic peaks, we were able to assign 4 out of 5 unknown samples correctly (i.e., 80% correctly diagnosed, 20% false-negative), and it would be 100% if we reject a possible outlier believed to be caused by an occlusion in the spinal CSF compartment. These findings are very promising, although the clinical relevance is not fully established due to the low number of unknown samples analyzed. In addition to the diagnostic potential, these results may be important steps towards understanding the neurodegenerative process.
Undersea Acoustic Communication and Navigation Technology Development and Demonstration (2006)

This final report contains a cumulative summary of project highlights included in the annual reports. It is provided primarily to meet contract close-out requirements, but also has a list of references and related projects. Additional information is available from the authors in addition to the published papers cited herein. The long-term goals of this program include the development of an integrated acoustic communication and long-baseline acoustic navigation system that supports the requirements of the Autonomous Operations FNC program. The goal of the AO-FNC focuses on a multi-vehicle solution to the Undersea Search and Survey (USS) mission, in particular that proposed by Bluefin Robotics. The Bluefin Robotics approach utilizes several types of vehicles, all linked acoustically, to carry out the target search mission. The long-term goals of the overall program include the demonstration of the multi-vehicle capability for mapping, target detection and classification, reacquisition and ultimately neutralization. The acoustic communication system will enable the vehicles to transfer both navigation and target information around the network, and to allow external command, control, and mission progress monitoring.
Establishing A-Priori Performance Guarantees for Robot Missions that Include Localization Software (2019)

One approach to determining whether an automated system is performing correctly is to monitor its performance, signaling when the performance is not acceptable; another approach is to automatically analyze the possible behaviors of the system a-priori and determine performance guarantees. Thea authors have applied this second approach to automatically derive performance guarantees for behavior-based, multi-robot critical mission software using an innovative approach to formal verification for robotic software. Localization and mapping algorithms can allow a robot to navigate well in an unknown environment. However, whether such algorithms enhance any specific robot mission is currently a matter for empirical validation. Several approaches to incorporating pre-existing software into the authors' probabilistic verification framework are presented, and one used to include Monte-Carlo based localization software. Verification and experimental validation results are discussed for real localization missions with this software, showing that the proposed approach accurately predicts performance.