gebhart/patrepeval huggingface dataset:
Multimodal Remote Home Monitoring of Lung Transplant Recipients during COVID-19 Vaccinations: Usability Pilot Study of the COVIDA Desk Incorporating Wearable Devices (2023)

<i>Background and Objectives</i>: Remote patient monitoring (RPM) of vital signs and symptoms for lung transplant recipients (LTRs) has become increasingly relevant in many situations. Nevertheless, RPM research integrating multisensory home monitoring in LTRs is scarce. We developed a novel multisensory home monitoring device and tested it in the context of COVID-19 vaccinations. We hypothesize that multisensory RPM and smartphone-based questionnaire feedback on signs and symptoms will be well accepted among LTRs. To assess the usability and acceptability of a remote monitoring system consisting of wearable devices, including home spirometry and a smartphone-based questionnaire application for symptom and vital sign monitoring using wearable devices, during the first and second SARS-CoV-2 vaccination. <i>Materials and Methods</i>: Observational usability pilot study for six weeks of home monitoring with the COVIDA Desk for LTRs. During the first week after the vaccination, intensive monitoring was performed by recording data on physical activity, spirometry, temperature, pulse oximetry and self-reported symptoms, signs and additional measurements. During the subsequent days, the number of monitoring assessments was reduced. LTRs reported on their perceptions of the usability of the monitoring device through a purpose-designed questionnaire. <i>Results</i>: Ten LTRs planning to receive the first COVID-19 vaccinations were recruited. For the intensive monitoring study phase, LTRs recorded symptoms, signs and additional measurements. The most frequent adverse events reported were local pain, fatigue, sleep disturbance and headache. The duration of these symptoms was 5-8 days post-vaccination. Adherence to the main monitoring devices was high. LTRs rated usability as high. The majority were willing to continue monitoring. <i>Conclusions</i>: The COVIDA Desk showed favorable technical performance and was well accepted by the LTRs during the vaccination phase of the pandemic. The feasibility of the RPM system deployment was proven by the rapid recruitment uptake, technical performance (i.e., low number of errors), favorable user experience questionnaires and detailed individual user feedback.
A New SRAM-Embedded Pixel Circuit That Modulates Accurately Gray Level for PWM-Driven Micro-LED Displays (2023)

A new analog pulse width modulation (A-PWM) pixel circuit is proposed for micro light-emitting diode (micro-LED) displays, which improves the accuracy of modulating gray level by efficient switching of its in-pixel static random access memory (SRAM). Varied gray levels are realized successfully with the integral of a constant current over corresponding designated duty for target gray. In practice, however, the imperfection of the current’s falling due to unavoidable switching delays results in nonlinear inaccuracy of displayed gray levels, undermining displaying quality. To remedy the problem, the proposed in-pixel SRAM is able to conduct faster switching than conventional pixel circuits for precise displaying of grays. The simulated results show the falling time is significantly reduced to 0.8ls from averaged 287ls of that without SRAM, obtained a near-constant gray output of 6.63nA*s/V. Based on experiments, the measured results show the DNL is improved from +0.05LSB-to-+0.78LSB to.0.09LSB-to-+0.14LSB, leading to the INL is reduced from the maximum +20.5LSB to +4.16LSB. In other words, the effectiveness offered by the proposed in-pixel SRAM in modulating accurately gray level is verified.
Interaction of Bovine Platelets with Bovine Glomerular Basement Membrane (1979)

The interaction of bovine platelets with bovine glomerular basement membrane has been studied by aggregometry, transmission and scanning electron microscopy and measurement of [3H] serotonin release. In the absence of added calcium platelets adhere to basement membrane but fail to undergo the release reaction or aggregation. In the presence of 0.2-0.5 mM calcium release of serotonin and complete aggregation of the platelets are observed when sufficient basement membrane is present. Platelets were strongly adhered to the basement membrane surface, the platelet surface in the aggregates closely following the surface of the basement membrane. Platelet morphology in aggregates with basement membrane closely resembled that of platelets from collagen-induced aggregates. Basement membrane differed from collagen in its requirement for calcium for the aggregation and release reactions. In addition purified basement membrane was 1.5-3 fold less active on a weight basis than bovine tendon collagen in promoting aggregation.
Respiratory syncytial virus infection in cyclophosphamide-treated cotton rats (1982)

Cotton rats infected intranasally with respiratory syncytial virus and immunosuppressed with cyclophosphamide shed virus for at least 7 weeks. Dissemination of virus beyond the respiratory tract was observed. In contrast, virus was recovered from infected, non-immunosuppressed rats for only 1 week, and only from the respiratory tract.
Interplay among recovery time, signal, and noise: Series- and parallel-tuned circuits are not always the same *This article is a US Government work and, as such, is in the public domain in the United States of America. (2000)

The quality factor, Q, of the magnetic resonance probe and the manner in which the probe is coupled to the spectrometer play important roles in the quality of the obtained experimental data, affecting the signal-to-noise ratio (SNR), the probe recovery time, radiation-damping, and the coupling between multiple coils. For example, high SNR often requires a high-Q probe, while a short recovery time to observe of broad signals generally requires low Q. Here, we discuss effecting a compromise between SNR and recovery time by adjusting the coupling of the probe and preamplifier by mismatching their impedances. Unlike the more common impedance-matched case, the conditions for optimum performance for parallel- and series-tuned probes are found to differ significantly. © 2000 John Wiley & Sons, Inc. Concepts Magn Reson 12: 125–136, 2000
Microwave Activation of Palladium Nanoparticles for Enhanced Ethanol Electrocatalytic Oxidation Reaction in Alkaline Medium (2015)

Abstract The impact of microwave irradiation on the structure and electrochemistry of monodispersed palladium nanoparticles is reported for the first time. When compared to the Pd that was not subjected to microwave treatment, the microwaved Pd nanocatalyst gave higher electrochemical active surface area ( EASA ≈67 m 2 g −1 ), aggregation/uniformity of dispersion, showed higher amount of the palladium oxides, and showed remarkable electrocatalytic behaviour towards ethanol oxidation reaction in alkaline medium (in terms of high mass activity, stability and fast reaction kinetics). The remarkable microwave‐induced properties on the Pd catalyst promise to revolutionize the use of microwave for catalyst activation for enhanced heterogeneous catalysis and fuel cell chemistry.
Numerical Solution of Prioritized Inverse Kinematics Using the Method of Sections (2019)

This paper proposes a new numerical solution of prioritized inverse kinematics using the method of sections. First of all, this paper shows the differential kinematics of the manipulator whose one of link is virtually disconnected. The proposed method is based on the differential kinematics. Next, the problems of applying the method of sections to the prioritized inverse kinematics are pointed out, and solutions of the problems are described. Finally, simulation experiments to compare the proposed method with the conventional method are performed, and the result shows that the proposed method is superior to the conventional method in terms of computation time.
Effect of sample stream radius upon light scatter distributions generated with a Gaussian beam light source in the sheath flow cuvette (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEffect of sample stream radius upon light scatter distributions generated with a Gaussian beam light source in the sheath flow cuvetteFahimeh. Zarrin and Norman J. DovichiCite this: Anal. Chem. 1987, 59, 6, 846–850Publication Date (Print):March 15, 1987Publication History Published online1 May 2002Published inissue 15 March 1987https://pubs.acs.org/doi/10.1021/ac00133a013https://doi.org/10.1021/ac00133a013research-articleACS PublicationsRequest reuse permissionsArticle Views118Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Multistep, effective drug distribution within solid tumors (2015)

The distribution of drugs within solid tumors presents a long-standing barrier for efficient cancer therapies. Tumors are highly resistant to diffusion, and the lack of blood and lymphatic flows suppresses convection. Prolonged, continuous intratumoral drug delivery from a miniature drug source offers an alternative to both systemic delivery and intratumoral injection. Presented here is a model of drug distribution from such a source, in a multistep process. At delivery onset the drug mainly affects the closest surroundings. Such 'priming' enables drug penetration to successive cell layers. Tumor 'void volume' (volume not occupied by cells) increases, facilitating lymphatic perfusion. The drug is then transported by hydraulic convection downstream along interstitial fluid pressure (IFP) gradients, away from the tumor core. After a week tumor cell death occurs throughout the entire tumor and IFP gradients are flattened. Then, the drug is transported mainly by 'mixing', powered by physiological bulk body movements. Steady state is achieved and the drug covers the entire tumor over several months. Supporting measurements are provided from the LODER system, releasing siRNA against mutated KRAS over months in pancreatic cancer in-vivo models. LODER was also successfully employed in a recent Phase 1/2 clinical trial with pancreatic cancer patients.
Mid-Infrared Polarization of the Diffuse Interstellar Medium toward CygOB2-12 (2022)

We present the first mid-IR detection of the linear polarization toward the star CygOB2-12, a luminous blue hypergiant that, with Av of ~10 mag of foreground extinction, is a benchmark in the study of the properties of dust in the diffuse interstellar medium. The 8-13 micrometer spectropolarimetry, obtained with the CanariCam multi-mode camera at the Gran Telescopio Canarias (GTC), shows clear trends with wavelength characteristic of silicate grains aligned in the interstellar magnetic field. The maximum polarization, detected with 7.8 statistical significance near 10.2 micrometers, is (1.24 +/- 0.28) % with position angle (126 +/- 8) deg. We comment on these measurements in the context of recent models for the dust composition in the diffuse interstellar medium.
Rethinking Rotation in Self-Supervised Contrastive Learning: Adaptive Positive or Negative Data Augmentation (2023)

Rotation is frequently listed as a candidate for data augmentation in contrastive learning but seldom provides satisfactory improvements. We argue that this is because the rotated image is always treated as either positive or negative. The semantics of an image can be rotation-invariant or rotation-variant, so whether the rotated image is treated as positive or negative should be determined based on the content of the image. Therefore, we propose a novel augmentation strategy, adaptive Positive or Negative Data Augmentation (PNDA), in which an original and its rotated image are a positive pair if they are semantically close and a negative pair if they are semantically different. To achieve PNDA, we first determine whether rotation is positive or negative on an image-by-image basis in an unsupervised way. Then, we apply PNDA to contrastive learning frameworks. Our experiments showed that PNDA improves the performance of contrastive learning. The code is available at https://github.com/AtsuMiyai/rethinking_rotation.
The effect of molecular aggregation of thermally activated delayed fluorescence sensitizers for hyperfluorescence in organic light-emitting diodes (2021)

DMAC-DPS showing AIE behavior increased TTA and STA, whereas Ph-OBNA showing ACQ behavior showed relatively small TTA and STA values due to the generation of excimers.
T cell-derived tumour necrosis factor is essential, but not sufficient, for protection againstMycobacterium tuberculosisinfection (2004)

Tumour necrosis factor (TNF) is critical for sustained protective immunity against Mycobacterium tuberculosis infection. To investigate the relative contributions of macrophage- and T cell-derived TNF towards this immunity T cells from wild-type (WT) or TNF-/- mice were transferred into RAG-/- or TNF-/- mice which were then infected with M. tuberculosis. Infected RAG-/- mice and RAG-/- recipients of TNF deficient T cells developed overwhelming infection, with extensive pulmonary and hepatic necrosis and succumbed with a median of only 16 days infection. By contrast, RAG-/- recipients of WT T cells showed a significant increase in survival with a median of 32 days. Although initial bacterial growth was similar in all groups of RAG-/- mice, the transfer of WT, but not TNF-/-, T cells led to the formation of discrete foci of leucocytes and macrophages and delayed the development of necrotizing pathology. To determine requirements for macrophage-derived TNF, WT or TNF-/- T cells were transferred into TNF-/- mice at the time of M. tuberculosis infection. Transfer of WT T cells significantly prolonged survival and reduced the early tissue necrosis evident in the TNF-/- mice, however, these mice eventually succumbed indicating that T cell-derived TNF alone is insufficient to control the infection. Therefore, both T cell- and macrophage-derived TNF play distinct roles in orchestrating the protective inflammatory response and enhancing survival during M. tuberculosis infection.
Enhanced Strobe Correlator Multipath Rejection for Code & Carrier (1997)

GPS multipath effects occur when reflected satellite
signals (from surfaces around or under the antenna)
interfere with the direct satellite signal. Multipath causes
receivers to make inaccurate measurements, or even lose
lock on the signal. Multipath conditions are always
present. For high precision GPS positioning, multipath is
still the single largest source of error.
There are several existing methods for reducing the effects
of multipath: among them the Edge Correlator
TM
and the better Strobe Correlator
TM
provide multipath rejection for
code only.
An even more advanced technique of Enhanced Strobe
Correlation
TM
is discussed here. This technique notably
provides C/A carrier phase multipath rejection and even
better C/A code rejection (particularly in the near
multipath). Since the method uses extra correlators built
into the ASIC, the firmware and hardware overhead is
minimal. The tradeoffs (greater complexity, significant
convergence time, potential noise observable degradation)
usually attached to other multipath rejection techniques,
are minimized.
Theoretical simulations and real-life results are presented
in this paper. We will show how the RTK techniques can
be greatly improved by this method.
We will also demonstrate that this method does not exhibit
the performance degradation which has been mentioned
for earlier mitigation schemes.
The Impact of Content Distribution on Structured P2P Networks in Mobile Scenarios (2006)

Structured Peer-to-Peer (P2P) networks are promising approaches for the use of P2P technologies in resource constrained environments such as mobile communication scenarios. The signaling overhead can be reduced significantly by using a hash function to map the nodes as well as the shared objects onto the same identifier space. Queries need not be flooded through the network but can be routed directly to the responsible node. This node stores references to all peers in the network providing the requested object. The mapping algorithm of the used protocol and the actual content distribution determine the number of object references one node is responsible for. This responsibility affects the maintenance traffic in structured P2P networks, as references (responsibilities) have to be shifted among nodes when a node joins or leaves the overlay. Especially in mobile scenarios a high amount of maintenance traffic heavily influences the system performance. Therefore the content distribution has great impact on the applicability of structured P2P approaches. In this paper, we present the results of our experimental analysis of content distribution in an existing large P2P network and its consequences for the structured P2P system Chord. Based on these results we evaluate the applicability of structured P2P networks in mobile scenarios.
Computationally efficient compression of audio signals by means of RIQ-DPCM (2002)

The need to transmit large amounts of data over limited bandwidth channels has resulted in many methods for digital data compression. The common approach is to identify and remove redundancy from the input data stream using knowledge of the source characteristics. In the case of signals intended for human observers (speech, music, pictures, etc.) it is also useful to consider the strengths and weaknesses of the human sensory systems in order to achieve a greater degree of data compression. Unfortunately, achieving perceptually transparent compression requires considerable computational resources. For situations requiring extremely low computational complexity without strictly transparent coding, such as multimedia applications on personal computer platforms, a new adaptive differential pulse code modulation (DPCM) data compression scheme is proposed. Although standard DPCM structures are widely used in single-talker speech coding systems, the models and statistical assumptions well-known for speech signals are not applicable to arbitrary audio signals such as music. The new DPCM formulation presented includes a recursively indexed quantizer (RIQ) to eliminate the problem of overload distortion, a simple predictor structure to take advantage of the short-term correlation present in wideband audio signals, and an adaptation strategy to optimize the system to the local statistics of the input signal. Thus, the new RIQ-DPCM formulation is presented as a computationally efficient means of wideband audio compression.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Sunless Tanning Products (2022)

Sunless tanning products, or self-tanners, are preparations that when applied topically impart a temporary coloration to the skin mimicking skin color of naturally sun-tanned skin. Refinements in the dihydroxyacetone (DHA) manufacturing process and advancements in formulation science have aided in the creation of formulations that produce a more natural-looking color and better longevity. The most widely used and most efficacious active ingredient in self-tanners is DHA. The content of DHA in self-tanning products depends on the desired browning intensity on the skin and is normally used in the range 4-8%. Amines and other nitrogen-containing compounds should be avoided in DHA-containing formulations. This includes collagen, urea derivatives, amino acids, and proteins. Sunless tanning products are available in numerous and convenient delivery vehicles, such as lotions, creams, gels, gelees, sprays, mousses, and towelettes. Modern day formulations are efficacious, well-tolerated, easy-to-use, and provide natural-looking results.
Differential Response of Adult and Embryonic Mesenchymal Progenitor Cells to Mechanical Compression in Hydrogels (2007)

Cells in the musculoskeletal system can respond to mechanical stimuli, supporting tissue homeostasis and remodeling. Recent studies have suggested that mechanical stimulation also influences the differentiation of MSCs, whereas the effect on embryonic cells is still largely unknown. In this study, we evaluated the influence of dynamic mechanical compression on chondrogenesis of bone marrow-derived MSCs and embryonic stem cell-derived (human embryoid body-derived [hEBd]) cells encapsulated in hydrogels and cultured with or without transforming growth factor beta-1 (TGF-beta1). Cells were cultured in hydrogels for up to 3 weeks and exposed daily to compression for 1, 2, 2.5, and 4 hours in a bioreactor. When MSCs were cultured, mechanical stimulation quantitatively increased gene expression of cartilage-related markers, Sox-9, type II collagen, and aggrecan independently from the presence of TGF-beta1. Extracellular matrix secretion into the hydrogels was also enhanced. When hEBd cells were cultured without TGF-beta1, mechanical compression inhibited their differentiation as determined by significant downregulation of cartilage-specific genes. However, after initiation of chondrogenic differentiation by administration of TGF-beta1, the hEBd cells quantitatively increased expression of cartilage-specific genes when exposed to mechanical compression, similar to the bone marrow-derived MSCs. Therefore, when appropriately directed into the chondrogenic lineage, mechanical stimulation is beneficial for further differentiation of stem cell tissue engineered constructs.
Introduction of a closed‐system cell processor for red blood cell washing: postimplementation monitoring of safety and efficacy (2015)

Safety and efficacy of washed RBCs were not affected after introduction of a closed-system cell processor. The ACP 215 allowed for an extended expiry time, improving inventory management and overall utilization of washed RBCs. Transfusion of fewer RBCs per episode reduced exposure of recipients to allogeneic blood products while maintaining efficacy.