gebhart/patrepeval huggingface dataset:
Video-Based Camera Localization Using Anchor View Detection and Recursive 3D Reconstruction (2021)

In this paper we introduce a new camera localization strategy designed for image sequences captured in challenging industrial situations such as industrial parts inspection. To deal with peculiar appearances that hurt standard 3D reconstruction pipeline, we exploit preknowledge of the scene by selecting key frames in the sequence (called as anchors) which are roughly connected to a certain location. Our method then seek the location of each frame in time-order, while recursively updating an augmented 3D model which can provide current camera location and surrounding 3D structure. In an experiment on a practical industrial situation, our method can localize over 99% frames in the input sequence, whereas standard localization methods fail to reconstruct a complete camera trajectory.
Discriminative training for complementariness in system combination. (2008)

There are few publications about demographics of Emergency Department (ED) burn patient visits. The purpose of this study was to compare ED only burn patients with admitted patients in an urban burn center. This was a retrospective review (1999 to 2014) of a burn unit patient registry. Patients were seen either in the Emergency Room or Trauma Bay (ED-TB) by staff, who determined whether the patient required admission or not. During this period, of the 5936 burn injury ED-TB encounters, there were 3754 (63%) admissions and 2182 (37%) ED-TB only (evaluation and discharge) visits. The median age was 30 years, and the %TBSA in the ED-TB only versus admitted patients was 1% vs 4% TBSA, P < .0001. Both groups had mainly scalding injuries in the kitchen. The majority of the ED-TB only patients presented with upper extremity burns (40%), whereas admitted patients had burns in multiple areas (49%). Most of the ED-TB only patients (73%) came to the hospital themselves, 23% were transferred from other hospitals, and 2% each, direct from the scene and clinic. In contrast, 53% of admitted patients were transferred from other hospitals, 29% came in on their own, and 11% were brought in direct from the scene, or from the burn clinic (7%), P = .0001. This review suggests that the main reason for non-admission of ED-TB only patients was the severity of injury; ED-TB only patients had a significantly less severe %TBSA (P < .0001), and fewer comorbidities compared to admitted patients.
Group 2 innate lymphoid cells and asthma (2015)

Group 2 innate lymphoid cells (ILC2s) are recently identified cell populations that produce type 2 cytokines such as IL-5 and IL-13 in response to epithelial cell-derived cytokines. Although ILC2s were initially reported to play a key role in the anti-helminth innate immunity, we now have greater interest in their role in asthma and other allergic diseases. In various asthma mouse models, ILC2s provoke eosinophilic inflammation accompanied by airway hyperresponsiveness independent of acquired immunity. Moreover, recent mouse studies show that ILC2s also promote acquired immunity and Th2 polarization, and various cytokines and lipid mediators influence the functions of ILC2s. Although ILC2s have also been identified in humans, studies on the role of human ILC2s in asthma are very limited. Thus far, human studies have shown that there is a slight difference in responsiveness and production of cytokines between mouse and human ILC2s, and it has been suggested that ILC2s are involved in allergic-type asthma and the exacerbation of asthma. In this review, we focus on mouse and human ILC2s, and discuss their role in asthma.
Unusual case of a swollen painful toe in a young man (2011)

History of the present illness A 25-year-old man with a history of epilepsy developed a gradually progressive swollen, red, and painful left first toe. There was no preceding trauma. There were no fevers or chills, and no other extremities were involved. He had never had these symptoms in the past. He was seen initially by his primary care provider, who diagnosed cellulitis and prescribed cephalexin 500 mg 3 times a day for 1 week, with no improvement. A trial of colchicine 0.6 mg twice a day was attempted for 1 week, but this also generated no improvement and a referral was made to rheumatology. At the initial rheumatologic evaluation the patient reported that his symptoms had started in September, and had been present for close to 2 months. He described the left first toe as “swelling up like a globe.” The second toe developed pain and swelling within 2–3 weeks, although not as severe. By 1 month the pain had spread to his left ankle. Walking was becoming much more difficult due to the pain. He was taking ibuprofen, with minimal improvement. He denied systemic symptoms. There was no eye redness or pain, no burning with urination or penile discharge, no back pain, and no nausea or vomiting, and his bowels were normal. There was no history of psoriasis.
A Coherent Phase Sequence Detection Scheme for SLM-based OFDM Systems without Side Information (2016)

OFDM 시스템을 위한 PAPR (peak-to-average power ratio) 저감 기법 중 하나인 SLM (selective mapping) 방식은 구현이 간단하고 전송 신호에 왜곡이 생기지 않는 매우 유용한 PAPR 저감 기법이다. 본 논문에서는 위상 신호에 대한 부가 정보(side information)를 전송하지 않는 SLM 기반 OFDM 시스템에 적용 가능한 동기식 위상 신호 검출 방식을 제시하고자 한다. 우선 동기식 합(coherent summation)에 기반하여 위상 신호를 검출할 수 있도록 하기 위해, 위상 신호의 일부를 직교 부호로 대치시키는 새로운 위상 신호 설계 방법을 제안한다. 또한 새로이 제안된 위상 신호에 기초하여 부가 정보가 필요 없는 동기식 위상 신호 검출 기준(detection criterion)을 제안한다. 컴퓨터 모의실험을 통해, 제안된 방식이 SLM 기반 OFDM 시스템에서 정상적으로 동작함을 보이고, 위상 신호 검출에 사용되는 부반송파 간 채널의 변화가 적은 환경에서 기존 방식보다 위상신호 검출 성능이 우수함을 보이고자 한다.
Glossiness of Colored Papers based on Computer Graphics Model and Its Measuring Method (2006)

In the case of colored papers, the color of surface effects strongly upon the gloss of its paper. The new glossiness for such a colored paper is suggested in this paper. First, using the Achromatic and Chromatic Munsell colored chips, the author obtained experimental equation which represents the relation between lightness V ( or V and saturation C ) and psychological glossiness Gph of these chips. Then, the author defined a new glossiness G for the colored papers, based on the above mentioned experimental equations Gph and Cook-Torrance's reflection model which are widely used in the filed of Computer Graphics. This new glossiness is shown to be nearly proportional to the psychological glossiness Gph. The measuring system for the new glossiness G is furthermore descrived. The measuring time for one specimen is within 1 minute.
Effects of adenosine 5′-monophosphate and adenosine 3′,5′-cyclic monophosphate on l cells (1975)

The adenine nucleotides, 5'-AMP and 3',5'-cyclic AMP block L cells in the S-phase of the cell cycle. The intracellular level of cyclic AMP is reduced after incubation of cells with 5'-AMP, and rates of uridine transport are increased after incubation with either 5'-AMP or cyclic AMP. On the contrary, cyclic AMP levels are increased and uridine transport decreased in cells treated with an inhibitor of the cyclic AMP phosphodiesterase. This inhibitor partially reverses the growth-inhibitory effect of cyclic AMP, indicating that a breakdown product is the effective inhibitor of growth. The inhibition of cell growth induced by the adenine nucleotides is prevented by uridine, suggesting that the block in S is due to a lack of availability of pyrimidines.
ChemInform Abstract: DIMETHYLALUMINUM METHYLSELENOLATE‐ A REMARKABLE REAGENT FOR THE PREPARATION OF ACTIVE ACYL‐TRANSFER AGENTS (1978)

Abstract Trimethylaluminium (I) reagiert mit Selen zu einem Einschiebungsprodukt (II), das mit den Estern (III) die Selenolester (IV) ergibt.
Keratinocytes and head and neck squamous cell carcinoma cells regulate urokinase-type plasminogen activator and plasminogen activator inhibitor-1 in fibroblasts. (2013)

SCC and NOK regulate fibroblast expression of genes involved in tumor stroma turnover differentially in vitro. These observations may contribute to a better understanding of the mechanisms behind extracellular matrix turnover in tumors.
Data from PD-1 and Tim-3 Regulate the Expansion of Tumor Antigen–Specific CD8<sup>+</sup> T Cells Induced by Melanoma Vaccines (2023)

&lt;div&gt;Abstract&lt;p&gt;Although melanoma vaccines stimulate tumor antigen–specific CD8&lt;sup&gt;+&lt;/sup&gt; T cells, objective clinical responses are rarely observed. To investigate this discrepancy, we evaluated the character of vaccine-induced CD8&lt;sup&gt;+&lt;/sup&gt; T cells with regard to the inhibitory T-cell coreceptors PD-1 and Tim-3 in patients with metastatic melanoma who were administered tumor vaccines. The vaccines included incomplete Freund's adjuvant, CpG oligodeoxynucleotide (CpG), and the HLA-A2–restricted analog peptide NY-ESO-1 157-165V, either by itself or in combination with the pan-DR epitope NY-ESO-1 119-143. Both vaccines stimulated rapid tumor antigen–specific CD8&lt;sup&gt;+&lt;/sup&gt; T-cell responses detected &lt;i&gt;ex vivo&lt;/i&gt;, however, tumor antigen–specific CD8&lt;sup&gt;+&lt;/sup&gt; T cells produced more IFN-γ and exhibited higher lytic function upon immunization with MHC class I and class II epitopes. Notably, the vast majority of vaccine-induced CD8&lt;sup&gt;+&lt;/sup&gt; T cells upregulated PD-1 and a minority also upregulated Tim-3. Levels of PD-1 and Tim-3 expression by vaccine-induced CD8&lt;sup&gt;+&lt;/sup&gt; T cells at the time of vaccine administration correlated inversely with their expansion &lt;i&gt;in vivo&lt;/i&gt;. Dual blockade of PD-1 and Tim-3 enhanced the expansion and cytokine production of vaccine-induced CD8&lt;sup&gt;+&lt;/sup&gt; T cells &lt;i&gt;in vitro&lt;/i&gt;. Collectively, our findings support the use of PD-1 and Tim-3 blockades with cancer vaccines to stimulate potent antitumor T-cell responses and increase the likelihood of clinical responses in patients with advanced melanoma. &lt;i&gt;Cancer Res; 74(4); 1045–55. ©2013 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
System design and performance of reconfigurableand simultaneous 2D multiple-plane WDM optical interconnects (1997)

A system design for reconfigurable and simultaneous 2D multiple-plane WDM optical interconnects has been investigated. Device characteristics such as detector responsivity shape, efficiency, and complexity affect the design requirements for wavelength separation and channel power. With decreasing wavelength separation, increased optical crosstalk and signal power loss result in performance penalties most notably for the middle wavelength channels. When signal power loss and optical crosstalk from the detection of undesired channels are evaluated, it is found that wavelength channel spacing down to 10 nm can be tolerated for the specific detector responsivity shape and efficiency attainable from currently available devices.
Pyrethroid Insecticide Comparison in Broccoli (1997)

Several pyrethroid insecticides were evaluated and compared for efficacy against lepidopterous insect pests in broccoli. Zeta-cypermethrin (Mustang®) was compared at two rates, tralomethrin (Scout X-tra®) formulations were compared, lambda-cyhalothrin (Karate®), and esfenvalerate (Asana®) were evaluated for efficacy against cabbage looper (Trichoplusia ni. CL). Following each of the applications, most of the treatments reduced the number of larger sized CL relative to the untreated check. The two rates of Mustang performed similarly as did the two formulations of Scout X-tra, emulsifiable concentrate versus gel.
193-nm lithography (Review Paper) (1996)

The trend in microelectronics toward printing features 0.25 micrometers and below has motivated the development of lithography at the 193-nm wavelength of argon fluoride excimer lasers. This technology is in its early stages, but a picture is emerging of its strengths and limitations. The change in wavelength from 248 to 193 nm will require parallel progress in projection systems, optical materials, and photoresist chemistries and processes. This paper reviews the current status of these various topics, as they have been engineered under a multi-year program at MIT Lincoln Laboratory.
A new waveform enabling enhanced QAM-FBMC systems (2015)

Multiple filter-banks enable QAM transmission and reception in filter-bank multi-carrier (FBMC) systems. In this paper, we propose a new method to design a set of simultaneously used base filters for QAM-FBMC by optimizing the trade-off between spectrum confinement and self-interference. The increased freedom in multiple base filter designs brings merits of a tailor-made spectrum confinement and desirable bit error performance simultaneously. Simulations results show the superiority of the proposed QAM-FBMC systems to other post-OFDM waveform candidates.
THER-11. BMI-1 MODULATION IMPAIRS DNA DAMAGE RESPONSE AND SENSITIZES DIPG CELLS TO IONIZING RADIATION (2019)

Diffuse intrinsic pontine glioma (DIPG) is a poor-prognosis brain tumor with no effective curative therapy. We previously identified BMI-1 as a potential therapeutic target in DIPG*. We have shown that BMI-1 is highly expressed in DIPG tumors and patient-derived cells regardless of histone subtype. In the present study, we used PTC596, a potent BMI-1 modulator recently entered into clinical trials. PTC596 treatment results in post-translational modification of BMI-1, affecting its downstream target H2AK119 mono-ubiquitination levels. BMI-1 has been shown to be one of the early proteins recruited to DNA damage sites during the process of DNA damage response (DDR). In DIPG cells treated with PTC596, we observed time and concentration dependent increase in both γH2AX phosphorylation levels and foci formation, indicating DNA double strand breaks (DSBs). Cell cycle analysis, cleaved caspase-3 and γH2AX staining showed a sequence of events leading to apoptosis of DIPG cells treated with PTC596. Moreover, the kinetics of DDR was impaired in DIPG cells treated with ionizing radiation (IR) in combination with PTC596. Both the foci formation and resolution were delayed resulting in further reduction in cell viability compared with either treatment alone. Our results suggest that PTC596-induced modulation of BMI-1 sensitizes DIPG cells to IR. This is the first report providing evidence supporting the effectiveness of IR in combination with BMI-1 modulation to treat DIPG. *Kumar, S.S. et al. BMI-1 is a Potential Therapeutic Target in Diffuse Intrinsic Pontine Glioma. Oncotarget 2017.
Development of anti-CD30 radioimmunoconstructs (RICs) for treatment of Hodgkin's lymphoma (2010)

In-vitro tumour cell affinities of all RICs were promising. However, in-vivo biokinetics tested in the mouse model did not meet expectations. This highlights the importance of developing and testing further new anti-CD30 conjugates.
Temporal and Spectral Nonlinear Absorption Characterization of a Hybrid Porphyrin-Squaraine-Porphyrin Macromolecule (2008)

The nonlinear absorption mechanisms of a porphyrin-squaraine-porphyrin macromolecule have been studied with femto/pico/nanosecond pulsewidths. Two-photon absorption of the macromolecule is ~10× larger than the constituents and is explained by intra-molecular charge transfer.
Knowledge Discovery from Layered Neural Networks based on Non-negative Task Decomposition (2018)

Interpretability has become an important issue in the machine learning field, along with the success of layered neural networks in various practical tasks. Since a trained layered neural network consists of a complex nonlinear relationship between large number of parameters, we failed to understand how they could achieve input-output mappings with a given data set. In this paper, we propose the non-negative task decomposition method, which applies non-negative matrix factorization to a trained layered neural network. This enables us to decompose the inference mechanism of a trained layered neural network into multiple principal tasks of input-output mapping, and reveal the roles of hidden units in terms of their contribution to each principal task.
An architecture for understanding in planning, action, and learning (1991)

FLOABN is an integrated architecture for an intelligent agent that brings together planning, execution, learning, spatial reasoning, and the interpretation of instructions in natural language form. The system runs in an environment based on a discrete event simulation that models the temporal extent and sequencing of events and actions. Overall, the goal of this architecture is to facilitate the integration of several capabilities within an intelligent agent. This architecture supports the coordination of high-level mental activities with low-level hand-eye motor routines, with particular emphasis on the role of understanding.
Ultrafast self-induced oscillation in a nonlinear subwavelength grating metamaterial ring resonator (2020)

The large refractive index of silicon enables sub-micron waveguide and high optical confinement. As a result, silicon photonic components could be made extremely compact, which is the foundation of the prosperous silicon photonics research. In the meantime, the large optical intensity within the waveguide, together with resonance structures, makes silicon photonics also an intriguing platform for studying phenomena involving high-order optical nonlinearities with low input power, such as two-photon absorption, four-wave mixing, stimulated Brillouin scattering, and free carrier absorption. Self-induced oscillation, also known as self-pulsing, is one of the phenomena induced by the interplay of multiple nonlinear processes. It happens when two or more contradict nonlinear effects interact and compete with each other. The oscillation theoretically can achieve &gt;50 GHz frequency, but due to the heating caused by free carrier absorption, the reported oscillation speeds are limited to MHz level. Even excited with pulsed lasers to suppress the self-heating effect, the oscillation only achieves ~3 GHz. In this paper, we show that through infiltrating the subwavelength grating metamaterial ring resonator with materials of negative thermo-optic coefficient and high third-order nonlinearity, the strong, but slow, thermal effect can be suppressed and therefore ultrafast phenomena become eminent. In this experiment, DDMEBT is used which has third-order susceptibility three orders of magnitude larger than fused silica. Oscillations with about 27 GHz frequency are demonstrated experimentally simply by exciting the ring resonator with a continuous working laser. The oscillation frequency is more than one order of magnitude faster than the fastest self-oscillation effect that has been observed.
Intramolecular alkoxypalladation/carbonylation of alkenes (1984)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIntramolecular alkoxypalladation/carbonylation of alkenesMartin F. Semmelhack and Christina BodurowCite this: J. Am. Chem. Soc. 1984, 106, 5, 1496–1498Publication Date (Print):March 1, 1984Publication History Published online1 May 2002Published inissue 1 March 1984https://pubs.acs.org/doi/10.1021/ja00317a059https://doi.org/10.1021/ja00317a059research-articleACS PublicationsRequest reuse permissionsArticle Views2153Altmetric-Citations157LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Rational design of amphiphile-based drug carriers and sterically stabilized carriers (1995)

This paper describes the parameters recommended for rational design of amphiphile-based drug carriers. The main advantage of a carrier is its ability to modify the pharmacokinetics and biodistribution of the drug, so that the drug level at the target is sufficient for therapeutic benefits. Three parameters are described. Two of them, the drug-to-carrier partition coefficient (KyiC) and the rate of drug release from the carrier (kff), are related to drug-carrier interactions; the third one is the rate of carrier clearance (kc). We demonstrate that carrier performance for drugs associated with the carrier amphiphile(s) is determined to a large extent by Kc, while for drugs encapsulated in the aqueous phase of the carrier it is important that koff will be similar to kc These conclusions are based on two examples: (i) Amphotericin B as a drug associated with five dosage forms which represent different types of amphiphile-based carriers: micelles (Fungizone), stable micelle-like disks (Amphocil), a complex with phospholipids (ABPLC), liposomes (AmBisome), and a submicronized emulsion, (ii) Liposomal doxorubicin which consisted of either doxorubicin associated with the membrane of negatively-charged, fluid oligolamellar liposomes (L-DOX) or doxorubicin loaded by an ammonium sulfate gradient into small, unilamellar, rigid liposomes having steric stabilizing lipid grafted in their lipid bilayer, (S-DOX). To better understand what contributes to k, we also describe the effect of bilayer acyl chain composition and the role of precipitation of the drug inside the liposomes.
Accelerated k‐space shift calibration for free‐breathing stack‐of‐radial MRI quantification of liver fat and (2021)

This proposed method may allow accelerated calibration for free-breathing stack-of-radial MRI PDFF and <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msubsup><mml:mi>R</mml:mi><mml:mn>2</mml:mn><mml:mo>∗</mml:mo></mml:msubsup></mml:math> mapping.
Multi-way Interacting Regression via Factorization Machines (2017)

We propose a Bayesian regression method that accounts for multi-way interactions of arbitrary orders among the predictor variables. Our model makes use of a factorization mechanism for representing the regression coefficients of interactions among the predictors, while the interaction selection is guided by a prior distribution on random hypergraphs, a construction which generalizes the Finite Feature Model. We present a posterior inference algorithm based on Gibbs sampling, and establish posterior consistency of our regression model. Our method is evaluated with extensive experiments on simulated data and demonstrated to be able to identify meaningful interactions in applications in genetics and retail demand forecasting.
Enzyme Activation with a Synthetic Catalytic Co‐enzyme Intermediate: Nucleotide Methylation by Flavoenzymes (2017)

Abstract To facilitate production of functional enzymes and to study their mechanisms, especially in the complex cases of coenzyme‐dependent systems, activation of an inactive apoenzyme preparation with a catalytically competent coenzyme intermediate is an attractive strategy. This is illustrated with the simple chemical synthesis of a flavin‐methylene iminium compound previously proposed as a key intermediate in the catalytic cycle of several important flavoenzymes involved in nucleic acid metabolism. Reconstitution of both flavin‐dependent RNA methyltransferase and thymidylate synthase apoproteins with this synthetic compound led to active enzymes for the C5‐uracil methylation within their respective transfer RNA and dUMP substrate. This strategy is expected to be of general application in enzymology.