gebhart/patrepeval huggingface dataset:
A self-consistent analytical model for non-collisional heating (1997)

Abstract. Non-collisional heating is an important phenomenon in low-pressure inductively coupled plasmas. In this paper, a self-consistent analytical model for non-collisional heating is developed which shows that non-collisional heating is a warm-electron effect that relies on a resonant interaction of electrons with the electromagnetic wave. Electrons with velocities comparable to the effective wave phase speed resonantly interact with the wave and gain net energy from it. Collisions randomize this directed energy thereby leading to electron heating. Non-collisional heating becomes more efficient if a larger proportion of electrons participate in the resonant interaction process. This can occur due to an increase in the electron temperature or decrease in the effective wave phase speed. Collisions destroy the essential phase correlation between the electrons and the wave, making the non-collisional heating process less efficient. 1.
High spatial frequency structured light imaging for intraoperative breast tumor margin assessment (2015)

A new superficial wide-field imaging technique is presented, which utilizes high spatial frequency structured illumination to constrain the light sampling volume to a sub-diffuse regime. In this transport regime, the effects of absorption are drastically reduced and the sensitivity to local scattering from ultrastructrual alterations is increased. Absorption independence is validated with multiple experiments including a bovine blood-Intralipid solution matrix and avian tissue with superficial bovine blood. The resulting structured light demodulated images show a complete insensitivity to the blood over Hb concentrations of 0 – 240 &mu;M. Increased sensitivity to ultrastructual changes is demonstrated by imaging avian tissue with controlled morphological alterations including formalin-induced crosslinking. This imaging technique is currently being translated towards intraoperative assessment of breast tumor margins because of its ability to capture an entire lumpectomy margin in a single field of view, insensitivity to confounding surface blood present on lumpectomies, and its inherent scatter signal without the need of any model inversion. Further, a new lumpectomy marking system is introduced that allows for both the surgeon to mark the lumpectomy during excision and optical assessment of the specimen after the margins have been marked. Structured light images acquired intraoperatively of all margins of lumpectomy specimens are presented to show feasibility of clinical translation. Immediate future work will focus on developing a multi-spectral system.
Toxicity and Repellency of Tephrosia candida to Larval and Adult Diaprepes Root Weevil (Coleoptera: Curculionidae) (2003)

Leaves of the tropical legume Tephrosia candida DC deterred feeding by adults of the Diaprepes root weevil, Diaprepes abbreviatus (L.), compared with leaves of Citrus macrophylla Wester, a common citrus rootstock, or T. vogelii Hook. f. When larvae were placed in pots containing plants of the three species for 28 d in a growth chamber, larval survival and weight gain were significantly reduced in pots containing plants of T. candida compared with larvae in pots with C. macrophylla or T. vogelii. Diet incorporation of lyophilized roots of T. candida into an artificial diet increasingly inhibited the growth of larvae and increased larval mortality with increased concentration of roots, whereas roots from C. macrophylla or T. vogelii had no effect compared with the diet-only control. T. candida, but not T. vogelii, contains at least one constituent that acts as an antifeedant toward adult D. abbreviatus and as a toxicant toward larvae. No antifeedant effect of roots of T. candida toward larvae was observed in no-choice pot tests or in a diet incorporation bioassay. In pots, larval feeding damage to roots of T. candida was evident. In the diet incorporation assay, 97% of larvae survived 29 d on a diet of cellulose powder (a nutritionally inert filler) despite losing weight. We conclude that decreased survival and weight gain of larvae-fed fresh or lyophilized roots of T. candida were the result of ingestion of a toxicant and not deterrence from feeding.
Distributed Rendering for Multiview Parallax Displays (2006)

3D display technology holds great promise for the future of television, virtual \nreality, entertainment, and visualization.\nMultiview parallax displays deliver stereoscopic views without glasses to \narbitrary positions within the\nviewing zone. These systems must include a high-performance and scalable 3D \nrendering subsystem in order\nto generate multiple views at real-time frame rates. This paper describes a \ndistributed rendering system for\nlarge-scale multiview parallax displays built with a network of PCs, commodity \ngraphics accelerators, multiple\nprojectors, and multiview screens. The main challenge is to render various \nperspective views of the scene and\nassign rendering tasks effectively. In this paper we investigate two different \napproaches: Optical multiplexing for\nlenticular screens and software multiplexing for parallax-barrier displays. We \ndescribe the construction of largescale\nmulti-projector 3D display systems using lenticular and parallax-barrier \ntechnology. We have developed\ndifferent distributed rendering algorithms using the Chromium stream-processing \nframework and evaluate the\ntrade-offs and performance bottlenecks. Our results show that Chromium is well \nsuited for interactive rendering\non multiview parallax displays.
K-ras and p16 Aberrations Confer Poor Prognosis in Human Colorectal Cancer (2001)

These results suggest that the combined K-ras and p16 analyses may be of prognostic use in human colorectal cancer.
Conformational Asymmetry in Poly(vinylcyclohexane) Containing Diblock Copolymers (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTConformational Asymmetry in Poly(vinylcyclohexane) Containing Diblock CopolymersMark D. Gehlsen and Frank S. BatesCite this: Macromolecules 1994, 27, 13, 3611–3618Publication Date (Print):June 1, 1994Publication History Published online1 May 2002Published inissue 1 June 1994https://pubs.acs.org/doi/10.1021/ma00091a024https://doi.org/10.1021/ma00091a024research-articleACS PublicationsRequest reuse permissionsArticle Views385Altmetric-Citations55LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Table S4 from TRK Fusions Are Enriched in Cancers with Uncommon Histologies and the Absence of Canonical Driver Mutations (2023)

&lt;p&gt;Supplemental Table 4. Patient level detail of use of immunotherapy in this cohort.&lt;/p&gt;
Induction of Preferential Helical Screw Senses in Optically Inactive Polysilanes via Chiral Solvation (2002)

Two optically active solvents were synthesised, (S)-(–)-2-methyl-1-propoxybutane and (S)-(–)-(2-methylbutoxymethyl)benzene. The main chain conformations of poly(methylphenylsilane) and poly(hexylmethylsilane) in these solvents were investigated using optical UV-visible and circular dichroism spectroscopy. It was observed that dissolving these inherently achiral polysilanes in optically active solvents induces the polymer chains to adopt preferred helical screw senses. This is the first example of induction of optical activity in conjugated polymers through chiral solvation.
The age of human mutation: genealogical and linkage disequilibrium analysis of the CLN5 mutation in the Finnish population. (1996)

Variant late infantile neuronal ceroid lipofuscinosis (vLINCL) is an autosomal recessive progressive encephalopathy of childhood enriched in the western part of Finland, with a local incidence of 1 in 1500. We recently assigned the locus for vLINCL, CLN5, to 13q21.1-q32. In the present study, the haplotype analysis of Finnish CLN5 chromosomes provides evidence that one single mutation causes vLINCL in the Finnish population. Eight microsatellite markers closely linked to the CLN5 gene on chromosome 13q were analyzed, to study identity by descent by shared haplotype analysis. One single haplotype formed by flanking markers D13S160 and D13S162 in strong linkage disequilibrium (P < .0001) was present in 81% of disease-bearing chromosomes. Allele 4 at the marker locus D13S162 was detected in 94% of disease-bearing chromosomes. To evaluate the age of the CLN5 mutation by virtue of its restricted geographical distribution, church records were used to identify the common ancestors for 18 vLINCL families diagnosed in Finland. The pedigrees of the vLINCL ancestors merged on many occasions, which also supports a single founder mutation that obviously happened 20 to 30 generations ago (i.e., approximately 500 years ago) in this isolated population. Linkage disequilibrium was detected with seven markers covering an extended genetic distance of 11 cM, which further supports the young age of the CLN5 mutation. When the results of genealogical and linkage disequilibrium studies were combined, the CLN5 gene was predicted to lie approximately 200 - 400 kb (total range 30 - 1360 kb) from the closest marker D13S162.
P‐174: The Electrical Properties of Transparent Emotional OLED Lighting Based on Organic Environment Sensor (2011)

Abstract This paper reports on a study of the electrical properties of integrated organic light emitting diode (OLED) with an organic photo sensor (OPS) based on poly‐3‐hexylthiophene (P3HT) and [6,6]‐phenyl‐C 61 butyric acid methyl ester (PCBM) for emotional lighting applications. The emission characteristics exhibit the changes in the current and luminance of an OLED as a function of time when the OPS is exposed to different illumination levels from full dark to 500 m W/cm 2 using a xenon lamp.
Analysis of Hematopoietic Stem Cell Transplant Engraftment (2011)

Polymorphic short tandem repeat (STR), or microsatellite, loci have been widely used to analyze chimerism status after allogeneic hematopoietic stem cell transplantation. The presence of a patient's DNA, as identified by STR analysis, may indicate residual or recurrent malignant disease or may represent normal hematopoiesis of patient origin. The ratio of patient-derived to donor-derived alleles is used to calculate the relative amount of patient cells (both benign and malignant) to donor cells. STRs on chromosomes known to be gained or lost in a patient's tumor are generally ignored because it is difficult to perform meaningful calculations of mixed chimerism. However, in this study, we present evidence that STR loci on gained or lost chromosomes are useful in distinguishing the benign or malignant nature of chimeric DNA. In the peripheral blood or bone marrow of 4 hematopoietic stem cell transplantation patients with leukemia or lymphoma, we identified tumor DNA on the basis of STR loci showing copy number alteration. We propose that a targeted evaluation of STR loci showing altered copy number in posttransplant chimerism analysis can provide evidence of residual cancer cells.
High Efficiency Amorphous Si Single Junction and Amorphous-Microcrystalline Si Tandem Solar Cells and Modules Fabricated Using Large Area PECVD Cluster Systems at High Deposition Rates (2008)

We report on recent developments of a-Si:H single junction (SJ) and a-Si:H/mc-Si:H tandem junction solar cells and modules fabricated using proprietary, field proven large scale AKT® RF-PECVD cluster tools. High quality a- Si:H and mc-Si:H absorber films were deposited at high deposition rates of 200-400Å/min and 300-600Å/min, respectively. Excellent uniformity of film thickness and properties over large area substrates was achieved, with better than ±10% for all of the substrate sizes (0.43−5.7 m2). Better than 5% uniformity of device parameters for both SJ and tandem cells were also achieved. a-Si:H SJ p-i-n cells with initial and stabilized efficiencies of 9.2±0.4% and 7.3±0.4%, respectively, were obtained on low cost, commercially mass fabricated floatline TCO glass. a-Si:H 30cm×30cm SJ modules were demonstrated with initial and stabilized efficiencies of &gt;8% and 6.6%, respectively. Incorporating high quality and stable a-Si:H on the top cells in a-Si:H/mc-Si:H tandem structure, initial and stabilized tandem cell efficiencies of 11.2±0.4% and 9.7±0.3%, respectively, were obtained on floatline TCO. Moreover, 11.6% initial tandem cell efficiency and 9.3% stabilized module (28cm×30cm) efficiency were demonstrated on offline TCO.
Purification and Properties of Carboxypeptidase G1 (1971)

Abstract An enzyme, carboxypeptidase G1, extracted from a strain of Pseudomonas stutzeri, has been isolated which hydrolyzes the carboxyl-terminal glutamate from both reduced and nonreduced folate derivatives, with Km values between 1.1 and 18.1 x 10-6 m. This enzyme also hydrolyzes the COOH-terminal glutamate of oligopeptides and N-benzyloxycarbonyl glutamates; it demonstrates lesser activity against aspartate COOH-terminal peptide linkages, with Km values of 1 to 5 x 10-4 m. The reverse reaction (pteroate + glutamate → folate) is also catalyzed, but at an equilibrium lying far toward hydrolysis. The enzyme has been purified 1050-fold. It has a broad pH optimum over the range of 6.3 to 7.3 and has a molecular weight of 92,000 as estimated by calibrated Sephadex gel filtration. On disc gel electrophoresis in 1% sodium dodecyl sulfate, purified preparations migrate as a single band of 46,000 molecular weight, indicating that the enzyme is a dimeric protein. The enzyme is activated by Zn++. Enzymic cleavage of 4-amino-N10-methylpteroylglutamic acid (methotrexate) was strongly inhibited by the product l-glutamic acid, and to a lesser extent by l-aspartic acid, while d-glutamic acid was ineffective. Competitive inhibition of methotrexate cleavage was also demonstrated by the substrates 4-aminopteroylaspartic acid, N-benzyloxycarbonyl glutamic acid, and N-benzyloxycarbonyl aspartic acid. Although certain properties of carboxypeptidase G1 were similar to those from other sources, several differences were noted between this enzyme and previously described carboxypeptidases.
High efficiency GaN-based light-emitting diodes with embedded air voids/SiO2nanomasks (2012)

In this paper, the high performance GaN-based light-emitting diodes (LEDs) with embedded microscale air voids and an SiO(2) nanomask by metal-organic chemical vapor deposition (MOCVD) were demonstrated. Microscale air voids and an SiO(2) nanomask were clearly observed at the interface between GaN nanorods (NRs) and the overgrown GaN layer by scanning electron microscopy (SEM). From the reflectance spectra we show strong reflectance differences due to the different refractive index gradient between the GaN grown on the nanotemplate and sapphire. It can increase the light extraction efficiency due to additional light scattering. The transmission electron microscopy (TEM) images show the threading dislocations were suppressed by nanoscale epitaxial lateral overgrowth (NELOG). The LEDs with embedded microscale air voids and an SiO(2) nanomask exhibit smaller reverse-bias current and large enhancement of the light output (65% at 20 mA) compared with conventional LEDs.
Pavement Design for Curved Road Sections Fatigue Performance of Interfaces and Longitudinal Top-down Cracking in Multilayered Pavements (2009)

International audience
Bottom-Up SiO2 Embedded Carbon Nanotube Electrodes with Superior Performance for Integration in Implantable Neural Microsystems (2012)

The reliable integration of carbon nanotube (CNT) electrodes in future neural probes requires a proper embedding of the CNTs to prevent damage and toxic contamination during fabrication and also to preserve their mechanical integrity during implantation. Here we describe a novel bottom-up embedding approach where the CNT microelectrodes are encased in SiO(2) and Parylene C with lithographically defined electrode openings. Vertically aligned CNTs are grown on microelectrode arrays using low-temperature plasma-enhanced chemical vapor deposition compatible with wafer-scale CMOS processing. Electrodes with 5, 10, and 25 μm diameter are realized. The CNT electrodes are characterized by electrochemical impedance spectroscopy and cyclic voltammetry and compared against cofabricated Pt and TiN electrodes. The superior performance of the CNTs in terms of impedance (≤4.8 ± 0.3 kΩ at 1 kHz) and charge-storage capacity (≥513.9 ± 61.6 mC/cm(2)) is attributed to an increased wettability caused by the removal of the SiO(2) embedding in buffered hydrofluoric acid. Infrared spectroscopy reveals an unaltered chemical fingerprint of the CNTs after fabrication. Impedance monitoring during biphasic current pulsing with increasing amplitudes provides clear evidence of the onset of gas evolution at CNT electrodes. Stimulation is accordingly considered safe for charge densities ≤40.7 mC/cm(2). In addition, prolonged stimulation with 5000 biphasic current pulses at 8.1, 40.7, and 81.5 mC/cm(2) increases the CNT electrode impedance at 1 kHz only by 5.5, 1.2, and 12.1%, respectively. Finally, insertion of CNT electrodes with and without embedding into rat brains demonstrates that embedded CNTs are mechanically more stable than non-embedded CNTs.
Unexpected Dissemination Patterns in Lymphoma Progression Revealed by Serial Imaging within a Murine Lymph Node (2012)

Non-Hodgkin lymphoma (NHL) is a heterogeneous and highly disseminated disease, but the mechanisms of its growth and dissemination are not well understood. Using a mouse model of this disease, we used multimodal imaging, including intravital microscopy (IVM) combined with bioluminescence, as a powerful tool to better elucidate NHL progression. We injected enhanced green fluorescent protein and luciferase-expressing Eμ-Myc/Arf(-/-) (Cdkn2a(-/-)) mouse lymphoma cells (EL-Arf(-/-)) into C57BL/6NCrl mice intravenously. Long-term observation inside a peripheral lymph node was enabled by a novel lymph node internal window chamber technique that allows chronic, sequential lymph node imaging under in vivo physiologic conditions. Interestingly, during early stages of tumor progression we found that few if any lymphoma cells homed initially to the inguinal lymph node (ILN), despite clear evidence of lymphoma cells in the bone marrow and spleen. Unexpectedly, we detected a reproducible efflux of lymphoma cells from spleen and bone marrow, concomitant with a massive and synchronous influx of lymphoma cells into the ILN, several days after injection. We confirmed a coordinated efflux/influx of tumor cells by injecting EL-Arf(-/-) lymphoma cells directly into the spleen and observing a burst of lymphoma cells, validating that the burst originated in organs remote from the lymph nodes. Our findings argue that in NHL an efflux of tumor cells from one disease site to another, distant site in which they become established occurs in discrete bursts.
Stereochemistry of the Macrocyclization and Elimination Steps in Taxadiene Biosynthesis through Deuterium Labeling (2005)

Taxadiene synthase catalyzes the cyclization of (E,E,E)-geranylgeranyl diphosphate (GGPP) to taxa-4(5),11(12)-diene (Scheme 1, 5 --> 2) as the first committed step of Taxol biosynthesis. Deuterated GGPPs labeled stereospecifically at C-1, C-4, and C-16 were synthesized and incubated with recombinant taxadiene synthase from Taxus brevifolia to elucidate the stereochemistry of the cyclization reaction at these positions. The deuterium-labeled taxadienes obtained from (R)-[1-(2H1)]-, (S)-[1-(2H1)]-, and [16,16,16-(2H3)]GGPPs (9, 10, and 23b) were established to have deuterium in the 2alpha and 2beta CH2 and 16CH3 positions, respectively, by high-field 1H NMR spectroscopy (eqs 1-3). Incubation of (R)-[4-(2H1)]GGPP (17) with the recombinant enzyme gave a 10:10:80 mixture of [5beta-(2H1)]taxa-3(4),11(12)-diene, [5beta-(2H1)]taxa-4(20),11(12)-diene, and unlabeled taxa-4(5),11(12)-diene according to GC/MS analyses of the products (eq 4). It follows that C-1 of GGPP underwent inversion of configuration, that the A ring cyclization occurs on the si face of C15, and that the terminating proton abstraction removes H5beta from the final taxenyl carbocation intermediate. Thus, the C1-C14 and C15-C10 bonds are formed on the opposite faces of the 14,15 double bond of the substrate, i.e., overall anti electrophilic addition. The implications of these findings for the mechanism of the cyclization and rearrangement are discussed.
General practitioner identification and retention for people with spinal cord damage: establishing factors to inform a general practitioner satisfaction measure (2020)

People with spinal cord damage (SCD) report a high level of GP use. There is a dearth of research investigating factors that contribute to GP identification and retention for people with SCD. Furthermore, a GP satisfaction measure developed specifically for people with SCD is non-existent. This preliminary study sought to identify factors contributing to GP identification and retention. A total of 266 people with SCD primarily based in Queensland, Australia, completed a cross-sectional survey that aimed to fill these knowledge gaps. Descriptive statistics and correlational analyses clarified the factors contributing to GP identification and GP retention respectively. An exploratory factor analysis utilising the principal components analysis method clarified a set of items that could underpin key domains for a SCD-specific GP satisfaction measure. The findings confirm that knowledge about SCD, physically accessible services, and trust are seminal considerations aligned with GP identification and retention for people with SCD.
Prevalence of dysfunctional but viable myocardium in patients with ischemic cardiomyopathy - results from clinical scans performed in 2010-2014 at four U.S. hospitals (2016)

Background Assessment of viability in patients with ischemic cardiomyopathy (ICM) prior to possible revascularization has fallen out of favor after the STITCH trial, which failed to demonstrate a benefit of echocardiography or nuclear viability testing. CMR assessment of viability by directly visualizing the transmural extent of both viable and nonviable myocardium offers unique advantages which have not been explored in large trials. Several small studies have shown significant contractile improvement after revascularization of dysfunctional segments with residual viability by CMR. The objective of this study was to determine the prevalence of residual viability over the entire range of severity of dysfunction in patients with ICM.
Effect of Cracking and Healing on Durability of Engineered Cementitious Composites Under Marine Environment (2007)

Peer Reviewed