gebhart/patrepeval huggingface dataset:
Probabilistic Medium Access Control for Full-Duplex Networks With Half-Duplex Clients (2017)

The feasibility of practical in-band full-duplex radios has recently been demonstrated experimentally. One way to leverage full-duplex in a network setting is to enable three-node full-duplex, where a full-duplex access point (AP) transmits data to one node yet simultaneously receives data from another node. Such three-node full-duplex communication, however, introduces inter-client interference, directly impacting the full-duplex gain. It hence may not always be beneficial to enable three-node full-duplex transmissions. In this paper, we present a distributed full-duplex medium access control (MAC) protocol that allows an AP to adaptively switch between full-duplex and half-duplex modes. We formulate a model that determines the probabilities of full-duplex and half-duplex access so as to maximize the expected network throughput. A MAC protocol is further proposed to enable the AP and clients to contend for either full-duplex or half-duplex transmissions based on their assigned probabilities in a distributed way. Our evaluation shows that, by combining the advantages of centralized probabilistic scheduling and distributed random access, our design improves the overall throughput by 1.53 times, on average, as compared with the greedy downlink-uplink client pairing.
A Highly Conserved Sequence Essential for Translational Repression of the Protamine 1 Messenger RNA in Murine Spermatids1 (2001)

Translational regulation of the protamine 1 mRNA is mediated by sequences in its 3' untranslated region. In this study, we demonstrate that a highly conserved sequence, the translational control element, is solely responsible for protamine 1 translational regulation. Mutation of the conserved sequence causes premature translation of a transgene containing a fusion between the human growth hormone coding sequence and the protamine 1 3' untranslated region. Temporal expression of the transgene was monitored in prepubertal animals by Northern and Western blotting and in adult animals by immunocytochemistry. Messenger RNAs lacking the translational control element sediment in the messenger ribonucleoprotein particle and ribosomal fractions of polysome gradients, suggesting that the translational control element is required for translational repression but not for incorporation of mRNAs into ribonucleoprotein particles.
Men Undergoing ICSI: Y We Do What We Do. (2001)

Absence of Deletion in Azoospermia (DAZ) Genes in Spermatozoa of Infertile Men with Somatic DAZ Deletions

de Vries JW, Repping S, Oates R, et al.

Fert Steril 2001;75:476–479 [PubMed]

Men with severe oligospermia and/or nonobstructive azoospermia (NOA) require intracytoplasmic sperm injection (ICSI) and in vitro fertilization if they are going to achieve paternity. However, one of the questions that remains unanswered is whether the “genetic” defect that supposedly caused the oligospermia and/or NOA is going to be passed on to the sons of these couples. There is evidence to suggest that deletions in the Y chromosome, which are de novo occurrences, are one of the major factors responsible for this spermatogenic defect. Recent data suggest that this deletion may be passed from father to son, but there has been no information regarding the probability of this event occurring. To help determine the likelihood that such a genetic abnormality may be passed from father to son with ICSI, de Vries et al collected sperm from seven men with either oligospermia or NOA and a deletion in the Y chromosome as seen in their peripheral cells and examined the sperm for this deletion. Using fluorescence in situ hybridization, it was found that all the sperm from these seven men carried the same deletion. This suggests that Y deletions are expressed in the Y sperm of men with this abnormality and that the probability of passing this from father to son is extremely high. These data suggest that all men undergoing ICSI as a result of oligospermia and/or NOA should be tested for the Y deletion and that genetic counseling should be part of the work-up of the couple with this finding.
Paramagnetic self‐assembled nanoparticles as supramolecular MRI contrast agents (2012)

Nanometer-sized materials offer a wide range of applications in biomedical technologies, particularly imaging and diagnostics. Current scaffolds in the nanometer range predominantly make use of inorganic particles, organic polymers or natural peptide-based macromolecules. In contrast we hereby report a supramolecular approach for the preparation of self-assembled dendritic-like nanoparticles for applications as MRI contrast agents. This strategy combines the benefits from low molecular weight imaging agents with the ones of high molecular weight. Their in vitro properties are confirmed by in vivo measurements: post injection of well-defined and meta-stable nanoparticles allows for high-resolution blood-pool imaging, even at very low Gd(III) doses. These dynamic and modular imaging agents are an important addition to the young field of supramolecular medicine using well-defined nanometer-sized assemblies.
[Presence of enteric viruses in non-diarrheic canine stools]. (1980)

Rota-, corona- and parvovirus particles have been visualized by direct electron microscopy in canine stools collected at random in Paris streets. A possible involvement of these viruses in gastroenteric diseases is discussed in the light of these findings.
Large Scale Practical Synthesis of Enantiomerically Pure cis-4-Amino-3-fluoro-1-methylpiperidine via Rhodium-Catalyzed Asymmetric Hydrogenation of a Tetrasubstituted Fluoroalkene (2021)

The development of multikilogram scale green and economical synthetic route of enantiomerically pure cis-4-amino-3-fluoro-1-methylpiperidine 1 is described. The synthesis features a highly regio-, chemo-, and enantioselective asymmetric hydrogenation of N-benzyl-4-((tert-butoxycarbonyl)amino)-5-fluoro-tetrahydropyridinium chloride 3. No purification or chiral enrichment is necessary due to the high selectivity resulting from proper selection of the catalyst system Rh(NBD)2(BF4) and Walphos 003. The crude product N-benzylpiperidine 4 was carried directly to N-methylpiperidine utilizing a highly effective one-pot debenzylation and reductive amination protocol. The target compound 1·2HCl was prepared in 66–68% overall yield with >99% ee and >98.5% purity from available compound 3-fluoropyridin-4-amine 2 with a process mass intensity of 150.
Low temperature boron and phosphorus activation in amorphous germanium using Ni- and Co-induced crystallization and its application for three-dimensional integrated circuits (2008)

In this work, we present very low temperature boron (B) and phosphorus (P) activation technique in amorphous (α)-Ge using nickel (Ni)- and cobalt (Co)-induced crystallization. Ni and Co not only crystallize an α-Ge film, they also facilitate activation of the respective B and P atoms in the α-Ge during the crystallization process at temperatures as low as 360 °C. The feasibility of the low temperature activation technique has been demonstrated for a Ge gate electrode in a Si P-channel metal-oxide-semiconductor field-effect transistor using Schottky Ni (or Co) silicide source/drain.
Conformation and stereodynamics of 2-dialkylamino-1,3-dioxa- and 3-methyl-1,3-oxaza- 2-phospholanes. A carbon-13 nuclear magnetic resonance and theoretical MNDO investigation (1984)

Rotation around the exocyclic P–NR2 bond in the title compounds (R = Me, Et, and Pri) has been frozen on the 13C n.m.r. time-scale at –100 to –150 °C. The exocyclic PNC coupling constants confirm that the preferred conformation has one NR group eclipsing the phosphorus lone pair and the other lying over the face of the ring; this geometry is also supported by MNDO SCF MO calculations. The P-NR2 rotational barriers, which lie in the range 6.0–9.2 kcal mol–1, increase in the sequence 1,3-dioxa- < 1,3-oxaza- < 1,3-diazaphospholane and also with increasing size of the NR group. MNDO calculations of the barrier height reproduce the former sequence. The cyclic POC and PNC coupling constants are discussed in relation to the ring conformation, and some 15N n.m.r. data are reported.
Search for the decay B0 → ϕμ+μ− (2022)

A bstract A search for the decay B 0 → ϕμ + μ − is performed using proton-proton collisions at centre-of-mass energies of 7, 8, and 13 TeV collected by the LHCb experiment and corresponding to an integrated luminosity of 9 fb − 1 . No evidence for the B 0 → ϕμ + μ − decay is found and an upper limit on the branching fraction, excluding the ϕ and charmonium regions in the dimuon spectrum, of 4 . 4 × 10 − 3 at a 90% credibility level, relative to that of the $$ {B}_s^0 $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msubsup><mml:mi>B</mml:mi><mml:mi>s</mml:mi><mml:mn>0</mml:mn></mml:msubsup></mml:math> → ϕμ + μ − decay, is established. Using the measured $$ {B}_s^0 $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msubsup><mml:mi>B</mml:mi><mml:mi>s</mml:mi><mml:mn>0</mml:mn></mml:msubsup></mml:math> → ϕμ + μ − branching fraction and assuming a phase-space model, the absolute branching fraction of the decay B 0 → ϕμ + μ − in the full q 2 range is determined to be less than 3 . 2 × 10 − 9 at a 90% credibility level.
Vasif Gerektiren Meslekleri Yapanların İş Tatmini: İstanbul Örneği (2016)

Gunumuzde calisma hayatinin belirgin sorunlarinin basinda is tatminsizligi ve bu sorunun beraberinde getirdigi performans ve verim dusuklugu gelmektedir. Bu calisma, beyaz yakali olarak da adlandirilan vasifli meslek sahiplerinin is tatmini seviyelerini, meslekleri ile ilgili beklenti ve tutumlarini degerlendirmektir. Ampirik arastirma Istanbul Ili merkez olmak uzere vasif gerektiren meslekleri yapan beyaz yakali calisanlar olarak adlandirilan 546 kisi uzerinde yapilmistir. Birinci bolumde is tatmini kavrami, tanimi ve onemi incelenmistir. Ikinci bolumde vasifli meslekleri yapan beyaz yakali calisan kavrami, tanimi ve ozellikleri incelenmistir. Ucuncu bolumde ise 546 gonullu beyaz yaka calisan tarafindan doldurulan anketlerin sonuclari degerlendirilmis olup yapilan ki-kare testlerinde is tatmini ile meslek ve diger degiskenlerle yapilan incelemeler ve kiyaslama tablolarinda anlamli ve olumlu veriler tespit edilmistir.
How to choose the optimal method of whole breast reconstruction (2020)

Many factors such as patient anatomy and personal desires as well as the need for radiotherapy have typically been used to choose the best method of whole breast reconstruction. The increase in demand for bilateral mastectomy, especially nipple-sparing mastectomy, has probably played a role in reduction of use of autologous tissue flaps for breast reconstruction. Selecting the optimal timing and technique for breast reconstruction after mastectomy requires knowledge of any anticipated oncology treatment. The advent of tabbed tissue expanders, acellular dermal matrix (ADM), and autologous fat grafting has enhanced the outcomes of implant-based breast reconstruction. The increasing use of autologous fat grafting has also contributed to enhanced aesthetic outcomes using implant-based breast reconstruction. Nipple-sparing mastectomy together with ADM more readily promotes symmetry with the contralateral normal breast when unilateral implant-based breast reconstruction is undertaken. Alloplastic tissue offers a reconstruction involving a less extensive procedure without the negative aspects of donor site morbidity.
Update on the mechanism of action and future of activated prothrombin complex concentrates. (2004)

Activated prothrombin complex concentrates (aPCCs) are an established treatment for bleeding in patients with inhibitors. These products are derived from prothrombin complex concentrates, purified from human plasma with dedicated activation steps included in their manufacturing process. Despite these activation steps, the majority of the prothrombin complex proteins remain as zymogens, with only a relatively small content of activated coagulation enzymes. Among these, the order of concentration based on activity units is the following: factor VIIa to factor Xa to thrombin to factor IXa. Studies in various in vitro and in vivo model systems indicate that the mechanism of action of aPCCs is primarily based on an enzyme-substrate complex consisting of factor Xa and prothrombin. These findings are complemented by others showing that prothrombin is a major procoagulant that is capable of triggering hemostasis under physiologic and pathophysiologic conditions. Despite the findings of the mechanism of action, aPCCs have a long history of successful clinical use, with established dosing regimens, and a relatively low risk of thromboembolic complications compared with other treatment options for patients with inhibitors.
The Impact of Surgeon Volume on Perioperative Outcomes in Hysterectomy (2014)

Hysterectomies performed by high-volume surgeons at our institution during the 3-year study period were associated with shorter operative times and less estimated blood loss.
Binge Ethanol and Liver: New Molecular Developments (2013)

Binge consumption of alcohol is an alarming global health problem. Binge (acute) ethanol (EtOH) is implicated in the pathophysiology of alcoholic liver disease (ALD). New studies from experimental animals and from humans indicate that binge EtOH has profound effects on immunological, signaling, and epigenetic parameters of the liver. This is in addition to the known metabolic effects of acute EtOH. Binge EtOH alters the levels of several cellular components and dramatically amplifies liver injury in chronically EtOH exposed liver. These studies highlight the importance of molecular investigations into binge effects of EtOH for a better understanding of ALD and also to develop therapeutic strategies to control it. This review summarizes these recent developments.
Scintillation and Dosimetric Properties of Cu-Doped Zinc Oxide Thin Films (2014)

Basic photoluminescence (PL), scintillation and thermoluminescence (TL) properties of Cu-doped ZnO thin films deposited by the Liquid Phase Epitaxy (LPE) method are reported. When the films were excited with 280 nm LED,the emission band was detected at 510 nm wavelength. This emission originated from the recombination between neutral shallow donor levels related to oxygen vacancy and the t2 energy level of excited Cu2+ (d9) accepter. The PL quantum efficiency was estimated to be about 3%. The pulse height spectra recorded under 241 Am alpha-ray irradiation indicated that the Cu-doped film had scintillation light yield greater than that of Bi4Ge3O12 (BGO) commercial scintillator. [DOI: 10.1380/ejssnt.2014.275]
Publisher's Note: Electrorotation of colloidal particles in liquid crystals [Phys. Rev. E72, 031704 (2005)] (2005)

Received 16 September 2005DOI:https://doi.org/10.1103/PhysRevE.72.039903©2005 American Physical Society
Interfacial electron-transfer reactions in colloidal semiconductor dispersions. Kinetic analysis (1982)

LPI
Adhesion enhancement of polymer-coated tin plate using atmospheric plasma treatment (2006)

Summary form only given. Adhesion characteristics of tin plate with polymer-coating is investigated after atmospheric plasma treatment. We have used atmospheric dielectric barrier discharge plasma for treatment and contact angle, XPS, SEM for surface analysis. It is observed that contact angle is decreased remarkably. It indicates surface energy is increased, that provides more driving force for adhesion. And we have observed that carbon ratio is decreased and at the same time oxygen ratio is increased. It is thought to be a carbon cleaning effect and oxidation effect which makes functional groups on the tin plate. It may cause the increase of adhesion. We have observed the enhancement of adhesion between tin plate and polymer coating as a result of taping test. Besides, the number of pin hole, which causes elusion of metal contents, is decreased. Therefore plasma treatment can be effective tool for adhesion enhancement of tin plate used for cans which contain edible foods
Involvement of MicroRNA-210 Demethylation in Steroid-associated Osteonecrosis of the Femoral Head (2016)

Angiogenesis is an important event in steroid-associated osteonecrosis of the femoral head (SONFH). Here we performed miRNA microarray with SONFH tissues (ONs) and the adjacent normal tissues (NLs) to select the angiogenic miRNA. The results showed that miR-210 was differentially expressed in SONFH versus normal tissues. Unexpectedly, its specific transcription factor, hypoxia-inducible factor-1α, was shown of no significant changes in ONs compared with NLs. Further Bisulfite sequencing revealed that miR-210 is embedded in a CpG island and miR-210 gene has 2 CpG sites with lower methylation percentage in ONs compared with NLs. Additionally, ONs with lower miR-210 gene methylation exhibited higher miR-210 expression. Next, we found that the endothelial cells treated with demethylating agents could significantly increase the expression of miR-210, along with promoted cell viability and differentiation. Some angiogenic genes (VEGF, bFGF, TNF-α and PCNA) were up-regulated as well. In addition, the supernatant of the cells after demethylation treatment displayed an enhanced ability of recruiting new microvessels in vivo. Taken together, our study not only provides novel insights into the regulation of angiogenesis in this disease, but also reveals a therapeutic opportunity for treatment of SONFH patients with demethylating agents.
Analysis of the Prevalence of Microsatellite Instability in Prostate Cancer and Response to Immune Checkpoint Blockade (2018)

The MSI-H/dMMR molecular phenotype is uncommon yet therapeutically meaningful in prostate cancer and can be somatically acquired during disease evolution. Given the potential for durable responses to anti-PD-1/PD-L1 therapy, these findings support the use of prospective tumor sequencing to screen all patients with advanced prostate cancer for MSI-H/dMMR. Because not all patients with the MSI-H/dMMR phenotype respond, further studies should explore mechanisms of resistance.
Single Molecule Studies of the Diffusion of Band 3 in Sickle Cell Erythrocytes (2016)

Sickle cell disease (SCD) is caused by an inherited mutation in hemoglobin that leads to sickle hemoglobin (HbS) polymerization and premature HbS denaturation. Previous publications have shown that HbS denaturation is followed by binding of denatured HbS (a.k.a. hemichromes) to band 3, the consequent clustering of band 3 in the plane of the erythrocyte membrane that in turn promotes binding of autologous antibodies to the clustered band 3, and removal of the antibody-coated erythrocytes from circulation. Although each step of the above process has been individually demonstrated, the fraction of band 3 that is altered by association with denatured HbS has never been determined. For this purpose, we evaluated the lateral diffusion of band 3 in normal cells, reversibly sickled cells (RSC), irreversibly sickled cells (ISC), and hemoglobin SC erythrocytes (HbSC) in order to estimate the fraction of band 3 that was diffusing more slowly due to hemichrome-induced clustering. We labeled fewer than ten band 3 molecules per intact erythrocyte with a quantum dot to avoid perturbing membrane structure and we then monitored band 3 lateral diffusion by single particle tracking. We report here that the size of the slowly diffusing population of band 3 increases in the sequence: normal cells<HbSC<RSC<ISC. We also demonstrate that the size of the compartment in which band 3 is free to diffuse decreases roughly in the same order, with band 3 diffusing in two compartments of sizes 35 and 71 nm in normal cells, but only a single compartment in HbSC cells (58 nm), RSC (45 nm) and ISC (36 nm). These data suggest that the mobility of band 3 is increasingly constrained during SCD progression, suggesting a global impact of the mutated hemoglobin on erythrocyte membrane properties.
Raptor Forward Error Correction (FEC) Schemes for FECFRAME (2012)

This document describes Fully-Specified Forward Error Correction (FEC) Schemes for the Raptor and RaptorQ codes and their application to reliable delivery of media streams in the context of the FEC Framework.The Raptor and RaptorQ codes are systematic codes, where a number of repair symbols are generated from a set of source symbols and sent in one or more repair flows in addition to the source symbols that are sent to the receiver(s) within a source flow.The Raptor and RaptorQ codes offer close to optimal protection against arbitrary packet losses at a low computational complexity.Six FEC Schemes are defined: two for the protection of arbitrary packet flows, two that are optimized for small source blocks, and two for the protection of a single flow that already contains a sequence number.Repair data may be sent over arbitrary datagram transport (e.g., UDP) or using RTP.
ERK1/2 Activation Induced by Inflammatory Cytokines Compromises Effective Host Tissue Integration of Engineered Cartilage (2009)

This study is the first to show the functional catastrophic effects of IL1-beta and TNF-alpha on the biochemical, structural, and integrative properties of tissue-engineered cartilage and their significant counteraction by the blockade of ERK signaling pathway. With the discovery of new potential chemical entities, ERK inhibitor may emerge as a new therapeutic approach for functional integration and mechanical integrity of an engineered cartilage to the host tissue and, therefore, enhance long-term viability and functionality of the restored joint surface.
Ultralow threshold on-chip toroidal microcavity nanocrystal quantum dot lasers (2006)

We demonstrate an on-chip toroidal microcavity nanocrystal quantum dot laser with a threshold energy below 10 femto-Joules at room temperature, a factor of 1 million lower than previously reported for strongly-confined, nanocrystal quantum dot lasers.
ChemInform Abstract: The Synthesis of GABAA Active Ligands by the Stille Process. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Testosterone Action, Deficiency, Substitution (2005)

No AccessJournal of UrologyBook Reviews1 Jun 2005Testosterone Action, Deficiency, Substitution Jacob RajferM.D. Jacob RajferJacob Rajfer More articles by this author View All Author Informationhttps://doi.org/10.1097/01.ju.0000163660.02216.beAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Testosterone Action, Deficiency, Substitution." The Journal of Urology, 173(6), p. 2210 Department of Urology University of California, Los Angeles Los Angeles, California© 2005FiguresReferencesRelatedDetails Volume 173Issue 6June 2005Page: 2210 Advertisement Copyright & Permissions© 2005MetricsAuthor Information Jacob Rajfer More articles by this author Expand All Advertisement PDF downloadLoading ...
Molecular genetics and biochemical mechanisms in bladder cancer. Oncogenes, tumor suppressor genes, and growth factors. (1992)

Transitional-cell carcinoma of the bladder is believed to arise through a series of genetic changes affecting cell growth and proliferation. Two basic types of such genes have been described: protooncogenes and tumor suppressor genes. The former have not been studied extensively in bladder cancer, although there is evidence that c-erb B-2/neu is overexpressed. Loss of specific chromosomal regions, which is common in bladder tumors, may inactivate tumor suppressor genes, of which p53 has received the most attention. Work also has been done on epidermal growth factor and its receptor, yielding evidence that malignant and normal urothelium have different sensitivities to its action. Although several advances must be made before genetic changes come to the clinical forefront, the information now being gained with such speed holds considerable promise for diagnosis and treatment.