gebhart/patrepeval huggingface dataset:
Locally-controlled domain microstructures in bismuth-iron-garnet films for magneto-optical current sensors. (2009)

Abstract not provided.
Synchronization in OFDM Systems Sensitivity to the Choice of Pulse Shape (1997)

Solved Problem: Symbol arrival time and carrier frequency offset estimation is addressed in an OFDM system using symbol extension with a cyclic prefix and employing pulse shaping. Originality of the work: Previous work has presented a method that without the use of pilots exploits the inherent correlation in the cyclically extended OFDM symbol in Gaussian channels. This contribution investigates what accuracy is achievable with this method in systems using pulse shaping. New results: The performance of the joint Maximum Likelihood estimator for a time and frequency offset is evaluated for different pulse shapes.
Analytical Perspective for Photonic Bound States in the Continuum (2013)

We investigate the formation of photonic bound states in the continuum (BICs) in photonic crystal slabs from an analytical perspective. Unlike the stationary at-$\Gamma$ BICs which origin from the geometric symmetry, the tunable off-$\Gamma$ BICs are due to the weighted destructive via-the-continuum interference in the vicinity of accidental symmetry when the majority of the radiation is pre-canceled. The symmetric compatible nature of the off-$\Gamma$ BICs leads to a trapping of light that can be tuned through continuously varying the wavevector. With the analytical approach, we explain a reported experiment and predict the existence of a new BIC at an unrevealed symmetry.
A translactonization route to macrocyclic lactones (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA translactonization route to macrocyclic lactonesE. J. Corey, Daniel J. Brunelle, and K. C. NicolaouCite this: J. Am. Chem. Soc. 1977, 99, 22, 7359–7360Publication Date (Print):October 1, 1977Publication History Published online1 May 2002Published inissue 1 October 1977https://doi.org/10.1021/ja00464a047RIGHTS & PERMISSIONSArticle Views551Altmetric-Citations49LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (273 KB) Get e-Alerts Get e-Alerts
Anisotropic Molecular Ionization at 1 V from Tellurium Nanowires (Te NWs) (2015)

Ionization of molecular species from one-dimensional (1D) tellurium nanowires (Te NWs) has been achieved at 1 V. Molecules with a range of chemical functional groups gave quality mass spectra with high signal/noise ratios and no fragment ions. Experiments suggest the possibility of emission of microdroplets of solution due to the intense fields at the ends or interfaces of nanostructures. It appears that electrolytic conduction of the solution wetting of the nanostructures and not the electronic conduction of the nanostructures themselves is involved in the ionization event. Anisotropy was seen when two-dimensionally aligned Te NWs were used for ionization. The orientation effect of aligned Te NWs on molecular ion intensity is demonstrated for many analytes including organic molecules and amino acids with experiments done using a silicon substrate having aligned Te NWs. These measurements suggest the possibility of creating a MS source that extends the applicability of mass spectrometry. Analysis of a variety of analytes, including amino acids, pesticides, and drugs, in pure form and in complex mixtures, is reported. These experiments suggest that 1D nanostructures in general could be excellent ionization sources.
Fabrication of Atomically Flat ScAlMgO4Epitaxial Buffer Layer and Low-Temperature Growth of High-Mobility ZnO Films (2010)

Atomically flat single-crystalline thin films of ScAlMgO4 (SCAM) were fabricated on yttria-stabilized zirconia (YSZ) (111) substrates by reactive solid-phase epitaxy using an ablation ceramic target with an optimized chemical composition. Owing to the good lattice matching, the SCAM layers enhanced two-dimensional growth of ZnO epitaxial films, suppressed the formation of threading dislocations at step edges, and provided larger Hall mobilities than those of ZnO films on YSZ and Al2O3 single-crystal substrates especially at low deposition temperatures <700 °C. The ZnO films exhibited Hall voltage anomaly at temperatures <140 K, which is explained by a two-layer model with a degenerated layer.
Data from The Human CD38 Monoclonal Antibody Daratumumab Shows Antitumor Activity and Hampers Leukemia–Microenvironment Interactions in Chronic Lymphocytic Leukemia (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; To establish a proof-of-concept for the efficacy of the anti-CD38 antibody daratumumab in the poor prognosis CD38&lt;sup&gt;+&lt;/sup&gt; chronic lymphocytic leukemia (CLL) subtype.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; The mechanism of action of daratumumab was assessed in CLL primary cells and cell lines using peripheral blood mononuclear cells to analyze antibody-dependent cell cytotoxicity (ADCC), murine and human macrophages to study antibody-dependent cell phagocytosis (ADCP), or human serum to analyze complement-dependent cytotoxicity (CDC). The effect of daratumumab on CLL cell migration and adhesion to extracellular matrix was characterized. Daratumumab activity was validated in two &lt;i&gt;in vivo&lt;/i&gt; models.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; Daratumumab demonstrated efficient lysis of patient-derived CLL cells and cell lines by ADCC &lt;i&gt;in vitro&lt;/i&gt; and ADCP both &lt;i&gt;in vitro&lt;/i&gt; and &lt;i&gt;in vivo&lt;/i&gt; whereas exhibited negligible CDC in these cells. To demonstrate the therapeutic effect of daratumumab in CLL, we generated a disseminated CLL mouse model with the CD38&lt;sup&gt;+&lt;/sup&gt; MEC2 cell line and CLL patient–derived xenografts (CLL-PDX). Daratumumab significantly prolonged overall survival of MEC2 mice, completely eliminated cells from the infiltrated organs, and significantly reduced disease burden in the spleen of CLL-PDX. The effect of daratumumab on patient-derived CLL cell dissemination was demonstrated &lt;i&gt;in vitro&lt;/i&gt; by its effect on CXCL12-induced migration and &lt;i&gt;in vivo&lt;/i&gt; by interfering with CLL cell homing to spleen in NSG mice. Daratumumab also reduced adhesion of CLL cells to VCAM-1, accompanied by downregulation of the matrix metalloproteinase MMP9.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; These unique and substantial effects of daratumumab on CLL viability and dissemination support the investigation of its use in a clinical setting of CLL. &lt;i&gt;Clin Cancer Res; 23(6); 1493–505. ©2016 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Predictive control technique of single inverter dual motor AC-brushless drives (2008)

The paper deals with controlled PM-brushless drives in configuration "ingle-inverter, dual-motor" operating with unbalanced loads at the shafts of the two motors. Predictive control technique is analyzed and two control circuits are compared. Starting from some simple control circuits which refer to an equivalent "single-inverter, single-motor" configuration, some modified blocks are added in order to improve steady-state and transient performances. Current and torque oscillation, total efficiency, torque-current ratio, dynamic response and stability are the main quantities observed. Their values are compared in order to evidence the advantages of the different examined control circuits.
Well-Defined Oligo(pyrrole-2,5-diyl)s by the Ullmann Reaction (1995)

The Ullmann coupling reaction has been used to polymerize N-t-BOC-2,5-dibromopyrrole into well-defined oligo(pyrrole-2,5-diyl)s. After optimization of the reaction conditions, i.e. using 1 wt equiv of Cu-bronze in DMF at 100 "C for 1 h, oligomers up to 25 repeating pyrrole units are obtained. Starting from 5,5‘- and 5,5"-dibrominated N-t-BOC protected bi- and terpyrrole as monomers, the polymerization is slower and a lower degree of polymerization is observed, yielding oligomers with an even lower molecular weight than those resulting from N-t-BOC-2,5-dibromopyrrole. The first 20 oligomers of poly(N-t-BOC-pyrrole)h ave been isolated by preparative HPLC. Characterization of the individual oligomers shows that they all are hydrogen terminated and possess a perfect 2,5-linkage: oligo(pyrro1e-2,5-diyl)s. The isolated oligomers have been used to study the optical and electrical properties of the oligomers as a function of chain length.
Temporal impulse responses from flicker sensitivities (1987)

We derive visual temporal impulse response functions from the large-field sinusoidal flicker sensitivity measurements made at several luminances by Kelly [J. Opt. Soc. Am. 51, 422 (1961)]. To this end we recognize response function causality and use Kramers-Krönig relations to reconstruct the (unmeasured) temporal phase spectrum and hence also the impulse response functions. At high luminances our derived functions are triphasic, while at low luminances they are biphasic. These functions are model independent, rely on no free parameters, and are consistent with certain theoretical model-dependent functions as well as psychophysical measurements by others.
Resistive-switching Solid-state Brain-neocortex-like Device for Advanced Non-volatile Logic Applications (2009)

A resistive-switching solid-state brain-neocortex-like device for advanced non-volatile logic applications was developed. This device can be used as a reconfigurable logic device that is operated by electrically connecting and disconnecting pairs of electrodes. This paper reports for the first time the experimental evaluation results of a three-terminal test element group as the unit for a solid state brain neocortex-like device. The solid-state brain-neocortex-like device was experimentally evaluated as unit in a three-terminal test element group. The evaluation results show that the neocortex-like reconfigurable switching, in particular, fringe-electric-field-induced switching is possible in the device.
Revival Actions in a Shooter Game (2013)

In this paper we present an analysis of revival actions in a third person shooter video game. We observe that players who revived their teammates played significantly more sessions. They appear also to be more skilled and successful in the game in terms of kills, wins, and deaths. We then discuss how to extend our analysis methodology to other types of social play as well as other games. Author Keywords video games; social play; online multiplayer
Approximated Optimal Design Using Local Polynominal Regression (2012)

In this paper, local polynominal regression is proposed as a metamodel for the optimal design. Local polynominal regression is often used for smoothing. Smoothing and approximation are applied for the different purpose, however these two methods are based on the similar theory. Therefore local polynominal regression is forecasted to be able to approximate functions. So the theory of local polynominal regression is extended to multivariate predictors for optimal design, and its effectiveness for approximation is verified. Next, more suitable optimization method that uses characteristics of local polynominal regression is suggested. Additionally, the comparison of local polynominal regression and other metamodels shows its features. As a result of the consideration, next four points are clarified. (1)LOESS that uses local quadratic regression and tricube weight function is most suitable for the approximation. (2)The metamodels based on local polynominal regression are able to use for the structural optimization and its characteristics are available for the optimization based on the gradient. (3)The accuracy of local polynominal regression is better than Kriging and RBF interpolation when the sample size is small. However, the property is reversed when the sample size is large. (4)The accuracy of local polynominal regression is better than Kriging and RBF interpolation when the response has noises. The fact shows local polynominal regression is suitable for the metamodel of montecarlo simulations and experiments.
Supplementary Methods, Table 1, Figures 1-9 from Combinations of BRAF, MEK, and PI3K/mTOR Inhibitors Overcome Acquired Resistance to the BRAF Inhibitor GSK2118436 Dabrafenib, Mediated by <i>NRAS</i> or <i>MEK</i> Mutations (2023)

&lt;p&gt;PDF file - 276K&lt;/p&gt;
Supplemental Figure 1 from Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer (2023)

&lt;p&gt;This figure provides an overview of the TEM results.&lt;/p&gt;
Balanced computing with nanophotonic interconnects (2008)

Amdahlpsilas law suggests that a system with balanced computation and communications perform the best under most circumstance-a 10 Teraflop chip would require an interconnect bandwidth of 100 Tb/s. We discuss low power and high productivity computing enabled by nanophotonic interconnects on chip.
Effects of omecamtiv mecarbil in heart failure with reduced ejection fraction according to blood pressure: the GALACTIC-HF trial (2022)

In GALACTIC-HF, risk reduction of heart failure outcomes with omecamtiv mecarbil compared with placebo was large and significant in patients with low SBP. Omecamtiv mecarbil did not affect SBP and was well tolerated independent of SBP values.
Soluble interleukin 2 receptors in polymyalgia rheumatica/giant cell arteritis. Clinical and laboratory correlations. (1992)

Serum levels of soluble interleukin 2 receptors (sIL-2R) were measured in 21 patients with polymyalgia rheumatica (PMR)/giant cell arteritis (GCA) prior to steroid treatment. These levels were significantly elevated in patients with PMR/GCA compared with healthy controls (p = 0.002). A significantly longer duration of morning stiffness (p = 0.005) was observed in patients with a high concentration of sIL-2R. A significant correlation was observed at diagnosis between sIL-2R and erythrocyte sedimentation rate (ESR) (p = 0.01) and between ESR and C-reactive protein (CRP) (p = 0.005). We investigated prospectively a group of 10 patients over a period of 6 months of prednisone therapy. At the end of the study sIL-2R levels fell significantly compared to pretreatment values (p = 0.02), but remained significantly higher compared to controls (p = 0.02). ESR and CRP values also fell significantly compared to pretreatment levels (p = 0.0001 in both cases). We observed a significant correlation between the decrease in ESR values and the decrease in sIL-2R and CRP levels after 6 weeks (p = 0.01 in both cases) and after 6 months of therapy (p = 0.002 and p = 0.05). sIL-2R may be considered a useful serologic marker for monitoring response to steroid therapy in patients with PMR/GCA. This laboratory variable correlated more closely with ESR than with CRP. The presence of elevated levels of sIL-2R is likely to reflect T cell activation occurring in PMR/GCA. T lymphocyte activation persisted after 6 months of steroid therapy, despite rapid and continuous control of disease manifestations.
Toward better benchmarking: challenge-based methods assessment in cancer genomics (2014)

Rapid technological development has created an urgent need for improved evaluation of algorithms for the analysis of cancer genomics data. We outline how challenge-based assessment may help fill this gap by leveraging crowd-sourcing to distribute effort and reduce bias.
Mathematical Test Effort Estimation for Dependability Assessment of Sensor-Based Driver Assistance Systems (2016)

The development of modern driver assistance systems in the automotive domain requires extensive testing, for safety as well as for legal reasons. This is especially the case for sensor-based systems that provide support for autonomous driving: if they fail, an accident may occur with fatal consequences. In the majority of cases, the required test effort is roughly estimated by means of previous project data, expert knowledge or based on economical factors. As an alternative, a general mathematical approach is presented in this paper, which is focused on black box systems with sensor data fusion. It enables new projects related with sensor data fusion to estimate the required test effort for a given scenario.
Well-differentiated Pancreatic Neuroendocrine Tumor in a Patient With Familial Atypical Multiple Mole Melanoma Syndrome (FAMMM) (2019)

Germline mutations in CDKN2A result in Familial Atypical Multiple Mole Melanoma Syndrome (FAMMM), which is associated with an increased risk for pancreatic ductal adenocarcinoma and melanoma. CDKN2A is somatically inactivated in multiple neoplasms, raising the possibility that, although the data are not conclusive, germline CDKN2A mutation may also impose an increased risk for other neoplasms. We present a patient with a CDKN2A germline mutation (p16-Leiden mutation) and mosaicism for neurofibromatosis type 2, who presented with a small asymptomatic pancreatic lesion, detected during endoscopic ultrasound screening of the pancreas. After resection, the lesion was found to be a well-differentiated pancreatic neuroendocrine tumor (PanNET). Molecular analysis of the tumor showed somatic loss of the second allele, supporting a causal relation of the PanNET to the underlying FAMMM syndrome. Recent data, showing the association between certain single-nucleotide polymorphisms in the CDKN2A gene and an increased incidence for PanNET, further support a role for germline CDKN2A alterations in PanNET risk. We conclude that PanNETs can be a phenotypic expression of FAMMM syndrome. This can have implications for screening and for the diagnosis of pancreatic neoplasms in carriers of germline CDKN2A mutations.
Quelle R&D Mener pour le Développement Des Réseaux D'énergie De Demain ? Les Propositions de L'ancre en 2015 (2015)

Feuille de route sur les réseaux électriques et stockage élaborée par le GP10 Réseaux et Stockages de l'Energie de l'ANCRE
<title>256 x 256 element HgCdTe hybrid IRFPA for 8- to 10-um band</title> (1995)

We developed a 256 by 256 element HgCdTe hybrid infrared focal plane array (IRFPA) for the 8 to 10 micrometer band. We used three technologies to develop this high-performance, long-wavelength, large-scale IRFPA. The first innovation was to glue a sapphire substrate to a thinned Si readout circuit to reduce the thermal expansion mismatch with a HgCdTe diode array fabricated on a CdZnTe substrate. The second was to fabricate an interlaced switched- FET readout circuit using a 3 micrometer CMOS process. This readout circuit has a storage capacity of more than 10<SUP>7</SUP> electrons and two video outputs capable of a 3.5 MHz data rate. The third was a HgCdTe diode array with an anodic sulfide passivation film and an optimized cutoff wavelength to reduce dark current and achieve high sensitivity. The noise equivalent temperature difference (NETD) was 0.06 K using f/2.5 optics. After 1000 thermal cycles (300 K - 80 K), there were no significant indium bump failures nor notable degradation in detector performance.
Increasing Production of Polyhydroxybutyrate in Sugarcane Plastids (2010)

The perception of health status is essential for better planning in health, not only due to its role as a determinant of health, but also because it is related with the adoption of health-promoting behaviours. The aim of the present study was to explore the relationship between lifestyles and self-rated health, in Portuguese elderly, according to their residence in rural or urban areas. We evaluated 80 individuals from Rebordelo, Trás-os-Montes (rural area) and 383 from Porto (urban area), with 60 or more years and with four or less years of education. Data were collected by trained interviewers, through a structured questionnaire, to evaluate social, demographic, health and behavioural characteristics. Anthropometric measures were also obtained. Leisure-time physical activity, tobacco, alcohol and fruit and vegetable consumption were the lifestyles evaluated. To evaluate self-rated health, each person rated their health status, according to five options (excellent, very good, good, reasonable or poor), later grouped into two: poor versus the others. Odds ratio (OR) and 95% confidence intervals (95%CI) were calculated by unconditional logistic regression, after adjustment for sex and education. About 41% of the elderly from the rural area and 32% from the urban area rated their health status as poor. In multivariate analysis, in the rural area, poor self-rated health was inversely associated with the practice of leisure-time physical activity (OR = 0.22, 95%CI 0.06-0.80). In urban area, alcohol consumption was associated with a lower probability of self-rating health as poor (considering not drinking as reference, >0-15 g alcohol/day: OR = 0.42, 95%CI 0.24-0.72; >15 g alcohol/day: OR = 0.60, 95%CI 0.32-1.11). In the rural area, a positive association between fruit and vegetable consumption and poor self-rated health was found (≥ 5 vs. <5 portions/day: OR = 5.21, 95%CI 1.14-23.83), while in the urban area there was an inverse association (OR = 0.75, 95%CI 0.45-1.25). Poor Self-rated health was inversely associated with leisure-time physical activity in the rural area, and with the consumption of alcoholic beverages in the urban area. The consumption of fruit and vegetables was associated with self-rated health in both populations, but while in the rural area the consumption of 5 or more servings per day was associated with a poor perception of health, in the urban area this association was in the inverse direction.
Secure Transmission With Interleaver for Uplink Sparse Code Multiple Access System (2018)

Sparse code multiple access (SCMA) is a promising air interface candidate technique for next generation mobile networks. By introducing the Tent map in the Chaos theory, we propose a novel physical layer transmission scheme with codeword level interleaving at the transmitter in this letter, which is termed as interleaver-based SCMA (I-SCMA). Simulation results and analysis show that I-SCMA can provide high security performance without any loss in performance and transmission rate, thus constitutes a viable solution for the next generation wireless networks to provide secure communications.
Demo (2015)

We demonstrate the first cloud-based solution for providing network security as a service in smart home IoT environments. Our solution uses Software-defined Networking (SDN) for controlling traffic flows inside the network and offloads traffic analysis tasks to a smart Cloud-based Traffic Analyzer (CbTA), which uses a crowd sourced knowledge base for detecting network threats and attacks. It is a scalable, cost-efficient, easily deployable as well as manageable solution for securing different network environments.
Adaptive temporal compressive sensing for video (2013)

This paper introduces the concept of adaptive temporal compressive sensing (CS) for video. We propose a CS algorithm to adapt the compression ratio based on the scene's temporal complexity, computed from the compressed data, without compromising the quality of the reconstructed video. The temporal adaptivity is manifested by manipulating the integration time of the camera, opening the possibility to realtime implementation. The proposed algorithm is a generalized temporal CS approach that can be incorporated with a diverse set of existing hardware systems.
Mater‐Bi: Biodegradable Material for Various Applications (2002)

Abstract Introduction Historical Outline Thermoplastic Starch Mater‐Bi Products on the Market Conclusions