MP06-14 IMPACT OF VISCERAL AND SUBCUTANEOUS ADIPOSE TISSUE ON POST DONATION RENAL FUNCTION IN LIVING KIDNEY DONORS (2017)

You have accessJournal of UrologyTransplantation & Vascular Surgery: Renal Transplantation & Vascular Surgery I1 Apr 2017MP06-14 IMPACT OF VISCERAL AND SUBCUTANEOUS ADIPOSE TISSUE ON POST DONATION RENAL FUNCTION IN LIVING KIDNEY DONORS Hyung Ho Lee, Sook Young Kim, Young Eun Yoon, Sung Ku Kang, Jae Yong Jeong, Kwang Hyun Kim, Kyung Hwa Choi, Joong Shik Lee, Koon Ho Rha, Young Deuk Choi, Sung Joon Hong, and Woong Kyu Han Hyung Ho LeeHyung Ho Lee More articles by this author , Sook Young KimSook Young Kim More articles by this author , Young Eun YoonYoung Eun Yoon More articles by this author , Sung Ku KangSung Ku Kang More articles by this author , Jae Yong JeongJae Yong Jeong More articles by this author , Kwang Hyun KimKwang Hyun Kim More articles by this author , Kyung Hwa ChoiKyung Hwa Choi More articles by this author , Joong Shik LeeJoong Shik Lee More articles by this author , Koon Ho RhaKoon Ho Rha More articles by this author , Young Deuk ChoiYoung Deuk Choi More articles by this author , Sung Joon HongSung Joon Hong More articles by this author , and Woong Kyu HanWoong Kyu Han More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2017.02.259AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES It was reported that some variables were revealed remain renal function after live donor nephrectomy. This study was conducted to determine the influence of visceral and subcutaneous adipose tissue on renal function in living kidney donors. METHODS Between July 2013 and February 2015, a total of 75 kidney donors who underwent living donor nephrectomy at our institution were analyzed. Visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) were measured at the level of the umbilicus using CT scan. The border of the intra-abdominal cavity was outlined on the CT image, the cross-sectional surface areas of the visceral fat and subcutaneous fat were calculated by a single urologist using Xelis CT software (INFINITT, Seoul, Korea)(Fig 1.). Renal function was estimated with the Modification of Diet in Renal Disease formula till six months after kidney donation. The relationship between preoperative visceral and subcutaneous adipose tissue and recovery of renal function was analyzed. RESULTS Thirty-three donors (44%) were male, and 13 (17.3%) grafts were secured from the right side. The mean BMI was 23.5±2.6 kg/m2 and the mean preoperative eGFR was 103.0±19.6 mL/min/1.73 m2. The mean VAT was 73.0±41.6cm3; SAT was 117.5±70.2cm3, and VAT/SAT ratio was 0.7±0.5. On multivariate linear regression, preoperative eGFR, ?eGFR, and VAT/SAT ratio were independently associated with eGFR at 6th month (Table 2). A ROC curve analysis showed that preoperative eGFR, ?eGFR and VAT/SAT ratio were highly predictive of developing of CKDIII at 6th month after donor nephrectomy (AUC = 0.933, p < 0.001). CONCLUSIONS Pre-donation eGFR, ?eGFR and V/S ratio are associated with the development of delayed renal recovery (GFR <60 ml/min/1.72m2) 6th month after donation. VAT/SAT ratio was associated with the postoperative renal function in living kidney donors. Kidney donors with higher VAT/SAT ratio require close observation, given their predisposition to CKD III after donation © 2017FiguresReferencesRelatedDetails Volume 197Issue 4SApril 2017Page: e78 Advertisement Copyright & Permissions© 2017MetricsAuthor Information Hyung Ho Lee More articles by this author Sook Young Kim More articles by this author Young Eun Yoon More articles by this author Sung Ku Kang More articles by this author Jae Yong Jeong More articles by this author Kwang Hyun Kim More articles by this author Kyung Hwa Choi More articles by this author Joong Shik Lee More articles by this author Koon Ho Rha More articles by this author Young Deuk Choi More articles by this author Sung Joon Hong More articles by this author Woong Kyu Han More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...