gebhart/patrepeval huggingface dataset:
Chemo-enzymatic cascade oxidation in supercritical carbon dioxide/water biphasic media (2009)

Enantioselective sulfoxidation was carried out by cascade reaction of Pd(0) catalysed formation of H2O2 and enzymatic oxidation using chloroperoxidase from Caldariomyces fumago. Supercritical carbon dioxide (scCO2) was used as medium for in situ generation of H2O2 directly from H2 and O2 using Pd-catalysts. Subsequently, H2O2 was utilised by the chloroperoxidase as an oxidant for the asymmetric sulfoxidation in the aqueous phase. This chemo-enzymatic cascade transformation exemplifies the potential of compartmentalisation of catalytic processes in multiphase systems.
Problems in the evaluation of polyvinylpyrrolidone (PVP) elution from polysulfone membrane dialyzers sterilized by gamma-ray irradiation (2016)

Adverse reactions, such as anaphylactoid shock, have been reported to occur frequently with the use of polysulfone (PSf) membrane dialyzers. Polyvinylpyrrolidone (PVP) elution from the membrane may be a key factor in these reactions. In this paper, we discuss the problems in the evaluation of PVP elution from PSf membrane dialyzers sterilized by gamma-ray irradiation. PVP concentrations in the filling solutions in some wet-type PSf membrane dialyzers are measured by Müller’s method as a standard measurement method. The PVP concentrations in autoclave (AC)-sterilized dialyzers were one order of magnitude higher than those in the solutions in dialyzers sterilized by gamma-ray irradiation. Because it is difficult to determine the PVP concentrations in the filling solutions sterilized by gamma-ray irradiation by Müller’s method, single-fractionated-component PVP solutions with fractionated components of PVP (K90 or K30) were prepared and the PVP concentrations of the solutions before and after gamma-ray irradiation were determined. The results indicated that the PVP concentrations in the solutions could be determined by Müller’s method before irradiation, whereas PVP was undetectable in the solution after irradiation. For single-fractionated-component PVP solutions with K90 and K30, the changes in the structure of PVP before and after gamma-ray irradiation were analyzed by high-performance liquid chromatography (HPLC). The single-fractionated-component PVP solutions with K90 and K30 had a broad peak at retention times of 15 and 19 min, respectively, prior to the gamma-ray irradiation, whereas both solutions showed a similar sharp peak at a retention time of 23 min after the irradiation. Based on these results, it is surmised that PVP is degraded by irradiation to yield PVP degradation products of low molecular weight. Furthermore, nuclear magnetic resonance (NMR) spectroscopy for PVP K90 solution was performed to confirm the signals from the vinylpyrrolidone (VP) skeletal structures. Signals from the VP skeletal structures were detected before the gamma-ray irradiation but disappeared after the irradiation. Thus, it appears that the degradation products of PVP without VP skeletal structures cannot be detected by Müller’s method. The measurement of PVP concentrations by Müller’s method is inappropriate for the evaluation of PVP elution from PSf membrane dialyzers sterilized by gamma-ray irradiation.
Low Birthweight Is Associated With Narrower Arterioles in Adults (2008)

Low birthweight is associated with increased risk of hypertension, but underlying mechanisms are obscure. We hypothesized structural microvascular alterations may be one such mechanism. We examined the association of birthweight and retinal arteriolar caliber in 3800 persons aged 51 to 72 years participating in a population-based study in 4 US communities (the Atherosclerosis Risk in Communities study). Participants reported full-term birth and their birthweight and had retinal photography. Retinal arteriolar and venular calibers were measured from digitized retinal photographs using a validated computer-assisted method. Lower birthweight was associated with narrower retinal arteriolar caliber, with each kg lower birthweight associated with 2.4 mum (95% confidence intervals, 1.3 to 3.5, P<0.001) narrower retinal arteriolar caliber, after controlling for age, gender, race, education, smoking, alcohol consumption, adult body mass index, and height. Additional adjustment for blood pressure averaged over the past 6 years and fasting glucose did not alter these findings, with each kg lower birthweight associated with a 1.7 mum (95% confidence intervals, 0.7 to 2.8, P<0.001) narrower retinal arteriolar caliber. This association was also present in persons without hypertension or diabetes. Lower birthweight was not associated with retinal venular caliber. These findings provide evidence that structural alterations in the arteriolar microcirculation may be a potential mechanism linking restricted fetal growth with subsequent risk of hypertension.
Reversible Morphology Control in Block Copolymer Films via Solvent Vapor Processing: An in Situ GISAXS Study (2010)

The real time changes occurring within films of cylinder-forming poly(α-methylstyrene-block-4-hydroxystyrene) (PαMS-b-PHOST) were monitored as they were swollen in tetrahydrofuran (THF) and acetone solvent vapors. In situ information was obtained by combining grazing incidence small angle X-ray scattering (GISAXS) with film thickness monitoring of the solvent vapor swollen films. We show that for self assembly to occur, the polymer thin film must surpass a swollen thickness ratio of 212% of its original thickness when swollen in THF vapors and a ratio of 268% for acetone vapor annealing. As the polymer becomes plasticized by solvent vapor uptake, the polymer chains must become sufficiently mobile to self assemble, or reorganize, at room temperature. Using vapors of a solvent selective to one of the blocks, in our case PHOST-selective acetone, an order-order transition occured driven by the shift in volume fraction. The BCC spherical phase assumed in the highly swollen state can be quenched by rapid drying. Upon treatment with vapor of a non-selective solvent, THF, the film maintained the cylindrical morphology suggested by its dry-state volume fraction. In situ studies indicate that self-assembly occurs spontaneously upon attaining the threshold swelling ratios.
A genome-wide transcriptional fingerprint of normal and malformed human hearts (2003)

Background— We present the first genome-wide cDNA array analysis of human congenitally malformed hearts and attempted to partially elucidate these complex phenotypes. Most congential heart defects, which account for the largest number of birth defects in humans, represent complex genetic disorders. As a consequence of the malformation, abnormal hemodynamic features occur and cause an adaptation process of the heart.\n\nMethods and Results— The statistical analysis of our data suggests distinct gene expression profiles associated with tetralogy of Fallot, ventricular septal defect, and right ventricular hypertrophy. Applying correspondence analysis, we could associate specific gene functions to specific phenotypes. Furthermore, our study design allows the suggestion that alterations associated with primary genetic abnormalities can be distinguished from those associated with the adaptive response of the heart to the malformation (right ventricular pressure overload hypertrophy). We provide evidence for the molecular transition of the hypertrophic right ventricle to normal left ventricular characteristics. Furthermore, we present data on chamber-specific gene expression.\n\nConclusions— Our findings propose that array analysis of malformed human hearts opens a new window to understand the complex genetic network of cardiac development and adaptation. For detailed access, see the online-only Data Supplement.
Ambiguity in induced polarization time constants and the advantage of the Pelton model (2022)

ABSTRACT The perceived differences between two popular relaxation models (referred to here as the “Cole-Cole model” and the “Pelton model”), along with their corresponding time constants, have been a source of confusion in recent spectral induced polarization (SIP) literature. These differences complicate comparisons among experimental results recorded by different researchers. A circuit model approach is adopted to better understand the differences among these relaxation models. Either relaxation model can fit SIP data sets equally well, the sole difference corresponds to the relaxation time that varies for the impedance and admittance formulations of the circuit models. The reporting of time constants from a common relaxation model will advance petrophysical investigations of the controls on SIP measurements when exploring databases compiled from previously published data sets.
Near-Infrared Spectral Analysis of Gas Mixtures (2002)

The analysis by near-infrared spectroscopy (NIR) of a series of gas mixtures approximating natural gases is reported. Wide variations of gas pressure and temperature are used in accord with conditions found in various utilitarian gas flow streams. The NIR analysis of CH 4 and CO 2 composition is found to be straightforward and depends only on compound mass density, but not explicitly on temperature, pressure, or composition. Linearity of the spectra of more complex mixtures is maintained, but the NIR analysis is more complex. Principal component analysis is shown to resolve composition for those gas mixtures.
Growth hormone release inhibiting hormone: actions on thyrotrophin and prolactin secretion after thyrotrophinreleasing hormone. (1975)

The hypothalamic tetradecapeptide growth hormone release inhibiting hormone (GH-RIH) blocked the thyrotrophin response to thyrotrophin-releasing hormone (TRH) in normal people and in patients with primary hypothyroidism. This inhibition was dose related. The TRH-induced prolactin release was not affected by GH-RIH. This dissociation of the thyrotrophin and prolactin responses to TRH by GH-RIH suggests that there are different mechanisms for release of thyrotrophin and prolactin and that only the former is affected by GH-RIH.
7T MRI detects deterioration in subchondral bone microarchitecture in subjects with mild knee osteoarthritis as compared with healthy controls (2014)

The results provide further support for the concept that poor subchondral bone quality is associated with osteoarthritis and may serve as a potential therapeutic target for osteoarthritis interventions. J. Magn. Reson. Imaging 2015;41:1311-1317. © 2014 Wiley Periodicals, Inc.
DC and RF Measurements of Serial Bi-SQUID Arrays (2012)

SQUID arrays are promising candidates for low-profile antennas and low-noise amplifier applications. We present the integrated circuit designs and results of dc and radio frequency measurements of wideband serial arrays based on the integration of linear bi-SQUID cells forming a superconducting quantum interference filter (bi-SQUID SQIF). Various configurations of serial array designs are described. The measured linearity, power gain, and noise temperature are analyzed and compared. The experimental results are matched to results of mathematical modeling. A serial bi-SQUID SQIF arrays are integrated into a coplanar waveguide, and symmetrically grounded to corresponding sides of the coplanar waveguide. The radio frequency output comes out from the central common line, which is also used for dc biasing, and forms a symmetrical balanced output. The signal and dc flux biasing line is designed as coplanar lines passed in parallel over each bi-SQUID cell in a bidirectional fashion concentrating magnetic flux inside of each cell. Serial bi-SQUID SQIF arrays are fabricated on 5 mm <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$\times$ </tex></formula> 5 mm chips using a standard HYPRES niobium 4.5 <formula formulatype="inline" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"><tex Notation="TeX">$ \hbox{kA/cm}^{2}$</tex></formula> fabrication process.
Feedstock Modification for Enhanced Additive Alloys (2020)

This project investigated the use of Y<sub>2</sub>O<sub>3</sub> nanoparticles to enhance IN625 feedstock for metal additive manufacturing. The oxide nanoparticles are adhered to the outer surface of the pre-alloyed IN625 powder feedstock, and serve to form an oxide dispersion strengthened (ODS) material in situ during processing. The conventional and enhanced feedstocks were processed using a laser powder bed fusion additive manufacturing (AM) system. The properties of the AM materials were characterized at elevated temperatures and compared to conventional wrought material. The addition of the Y<sub>2</sub>O<sub>3</sub> nanoparticles improved the yield strength, stress rupture, and corrosion properties of the AM material, and compared more favorably with conventional wrought IN625. This research will enable future adoption of additively manufactured ODS-IN625 components with superior properties to current printed IN625 material.
Reducing TNF Receptor 2+ Regulatory T Cells via the Combined Action of Azacitidine and the HDAC Inhibitor, Panobinostat for Clinical Benefit in Acute Myeloid Leukemia Patients (2013)

Our study provides for the first time, in vivo validation of the ability of panobinostat in combination with azacitidine to suppress prevalent TNFR2(+) Tregs, resulting in clinical benefits within patients with AML.
Theoretical studies of the photexcited state Cu atom reactions. II. The Cu*+H2→CuH+H photochemical reaction (1984)

Pseudopotential SCF-LCAO-MO including extensive variational and perturbative CI calculations have been done for the side-on Cu(2S, 2P, 2D)+H2(1Σ+g )→CuH(1Σ+)+H(2S) photochemical reaction. Nine low-lying states that result from these interactions have been considered. From these nine those that correspond to the 2B2 and 2A1 representations of the C2v symmetry are analyzed in full detail; first because the HCuH intermediate has a 2B2 electronic ground state and secondly because a 2A1 state correlates with the ground states of the reactants and products (Cu+H2 and CuH+H). We analyze the possible structures of the CuH2 intermediate molecule and discuss the reasons why such species is not observed under the matrix isolation experimental conditions of the photoinduced chemical reaction.
Enhancing Food Safety, Product Quality, and Value-Added in Food Supply Chains Using Whole-Chain Traceability (2016)

A robust whole chain traceability system can limit consumers’ exposure to potentially hazardous foods, improve supply chain management, and add value to consumer products. However, fragmented supply chains present special challenges. In the beef industry, for example, producers have resisted participation in whole chain traceability because of high cost relative to value and concerns about disclosing proprietary information, among others. A multi-disciplinary team from universities, private firms, and a foundation has developed and tested a pilot proprietary centralized data whole chain traceability system that addresses many of these obstacles. This system would facilitate a precision agriculture approach to beef production and marketing. While the remaining challenges are serious, the benefits to society, consumers, and businesses from widespread adoption of whole-chain traceability systems are potentially large.
High-temperature nanophosphors for white-light-emitting diodes (2011)

Single chip white-LEDs are necessary in future optimal lighting applications for daylight quality lighting and energy efficiency. InGaN/GaN-based blue LEDs with nanophosphors encapsulated in silicone can effectively render daylight quality illumination.
A New One-Pot, Four-Component Synthesis of 1,2-Amino Alcohols: TiCl3/t-BuOOH-Mediated Radical Hydroxymethylation of Imines (2008)

An amine, an aldehyde, and methanol can be readily assembled in one pot under very mild conditions through a free-radical multicomponent reaction by using an aqueous acidic TiCl3/t-BuOOH system to afford 1,2-amino alcohols in fair to excellent yields.
Single Negative, Double Negative, Low Loss Negative (2007)

We deliberately control one or several parameters out of the quadruple of imaginary and real parts of permittivity and permeability. Optical magnetism throughout the visible range and dual band negative index metamaterials were discussed.
Heterogeneous electron transfer at designed semiconductor/liquid interfaces. Rate of reduction of surface-confined ferricenium centers by solution reagents (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTHeterogeneous electron transfer at designed semiconductor/liquid interfaces. Rate of reduction of surface-confined ferricenium centers by solution reagentsNathan S. Lewis, Andrew B. Bocarsly, and Mark S. WrightonCite this: J. Phys. Chem. 1980, 84, 16, 2033–2043Publication Date (Print):August 1, 1980Publication History Published online1 May 2002Published inissue 1 August 1980https://pubs.acs.org/doi/10.1021/j100453a008https://doi.org/10.1021/j100453a008research-articleACS PublicationsRequest reuse permissionsArticle Views195Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
N-Heterocyclic Carbene-Stabilized Gold Nanoparticles: Mono- Versus Multidentate Ligands (2021)

Over the past decade, N-heterocyclic carbenes (NHCs) have attracted remarkable attention as metal-coordinating ligands because of their ability to strongly interact with transition metal complexes and surfaces. We investigate the coordination interaction between colloidal gold nanoparticles (AuNPs) and three sets of hydrophilic NHC-based ligands: an amine-modified small molecule, a monomeric NHC appended with a poly(ethylene glycol) (PEG) block, and a modified poly(isobutylene-alt-maleic anhydride), PIMA, that simultaneously presents multiple NHC groups and several short PEG chains. In this report, we find that all three ligands can rapidly coordinate onto AuNPs, as characterized using a combination of NMR spectroscopy, high-resolution transmission electron microscopy, and dynamic light scattering. These measurements have been supplemented with colloidal stability tests as well as competition from dithiothreitol molecules. Overall, we find that multidentate NHC polymer coating exhibits the highest affinity to AuNPs, which manifests in long-term colloidal stability in buffer media, absence of any aggregation, and better resistance to competition from reducing molecules. We further exploit these data to infer additional insights into the interaction and coordination of NHC molecules with Au surfaces.
CROSSLINKING OF SATURATED ELASTOMERS WITH DIAZIDES. PART I: MECHANICAL PROPERTIES OF VULCANIZATES (2011)

Abstract For vulcanization of fully saturated elastomers peroxide/coagent systems are commonly applied. Problems encountered with peroxides however, are reduced efficiency, especially in the presence of plasticizing oils, and unwanted side reactions. In this paper diazides are presented as alternatives to peroxide vulcanization systems, particularly in combination with the use of plasticizing oils. The performance of three diazides; tri(ethylene glycol)-di(azidoformate) (GDAF), 4,4 ′ -isopropylidenediphenyl azidoformate (4,4 ′ DAF) and 1,3-benzenedisulfonyl azide (1,3BDSA) is investigated. For the evaluation of the practical product performance, carbon black filled and oil extended compounds of EPM and EPDM-rubbers are used. It is also investigated how the presence of carbon black and plasticizing oil influences the diazide reaction kinetics.
Visualization of vortex mode bifurcation on Taylor vortex flow using ultrasonic measurement (2005)

In this study, experiment was carried out for Taylor-Couette vortex flow between a rotating inner cylinder and a fixed outer cylinder with small aspect ratio. It is two concentric rotating cylinders with a 25mm gap in aspect ration 3 and radial ratio 0.375 by mean of an ultrasonic velocity profiler (UVP). Successive instantaneous and mean velocity profiles were obtained by an ultrasonic Doppler velocity profile method, and the spatio-temporal velocity field had been the four-cell mode, N-2Cell, N-4Cell, A-3Ce11 and A-4Cell mode.
Effects of Agitation Milling of a Starting Mixture on the Solid-state Synthesis and Properties of BaTiO3. (2000)

Effects of agitation milling of either TiO2 or a mixture of TiO2 and BaCO3 on the solide-state synthesis and properties of BaTiO3 are studied. Milling TiO2 produces the surface defects. For a mixture of TiO2 and BaCO3, milling brings not only high compositional homogeneity but also forms BaTiO3 precursor. The rate of formation of BaTiO3 is examined by high temperature X-ray diffraction analysis. Synthesis of BaTiO3 is accelerated by compositional homogeneity and BaTiO3 precursor formation from the stating mixture by agitation milling. BaTiO3 powders that have been mechanically treated starting mixture, and calcined at 1100°C comprise homogeneous spherical particles with narrow particle size distribution.
Electrospray Photochemical Oxidation of Proteins (2019)

Photooxidation of peptides and proteins by pulsed ultraviolet laser irradiation of an electrospray in the ion source of a mass spectrometer was demonstrated. A 193-nm excimer laser at 1.5-mJ pulse energy was focused with a cylindrical lens at the exit of a nanoelectrospray capillary and ions were sampled into a quadrupole time-of-flight mass spectrometer. A solution containing a peptide or protein and hydrogen peroxide was infused into the spray at a flow rate of 1 μL/min using a syringe pump. The laser creates OH radicals directly in the spray which modify biomolecules within the spray droplet. These results indicate that photochemical oxidation of proteins can be initiated directly within electrospray droplets and detected by mass spectrometry.
Online spectrum cartography via quantized measurements (2015)

An online spectrum cartography algorithm is proposed to reconstruct power spectral density (PSD) maps in space and frequency based on compressed and quantized sensor measurements. The emerging interpolation task is formulated as a nonparametric regression problem in a reproducing kernel Hilbert space (RKHS) of vector-valued functions, and solved using a stochastic gradient descent iteration. Numerical tests verify the map estimation performance of the proposed technique.