gebhart/patrepeval huggingface dataset:
Material Swapping for 3D Scenes using a Learnt Material Similarity Measure (2022)

We present a method for augmenting photo-realistic 3D scene assets by automatically recognizing, matching, and swapping their materials. Our method proposes a material matching pipeline for the efficient replacement of unknown materials with perceptually similar PBR materials from a database, enabling the quick creation of many variations of a given 3D synthetic scene. At the heart of this method is a novel material similarity feature that is learnt, in conjunction with optimal lighting conditions, by fine-tuning a deep neural network on a material classification task using our proposed dataset. Our evaluation demonstrates that lighting optimization improves CNN-based texture feature extraction methods and better estimates material properties. We conduct a series of experiments showing our method’s ability to augment photo-realistic indoor scenes using both standard and procedurally generated PBR materials.
Energetics-based design of small flapping-wing micro air vehicles (2006)

The energetics of a flapping-wing micro air vehicle (MAV) is analyzed with the objective of designing it. The salient features of this paper are as follows: 1) designing an energy storage mechanism in the air vehicle similar to an insect thorax that stores part of the kinetic energy of the wing as elastic potential energy during a flapping cycle; 2) inclusion of simplified aerodynamic wing models and inertia of the mechanism using rigid-body modeling techniques; 3) optimization of parameters of the energy storage mechanism using the dynamic models, so that energy input from the external actuators is minimized during a flapping cycle. A series of engineering prototypes based on these studies have been planned which will justify the use of these mathematical techniques.
Atomic Layer Etching of HfO2Using Sequential, Self-Limiting Thermal Reactions with Sn(acac)2and HF (2015)

The atomic layer etching (ALEt) of HfO2 was performed using sequential, self-limiting thermal reactions with tin(II) acetylacetonate (Sn(acac)2) and HF as the reactants. The HF source was a HF-pyridine solution. The etching of HfO2 was linear with atomic level control versus number of Sn(acac)2 and HF reaction cycles. The HfO2 ALEt was measured at temperatures from 150–250°C. Quartz crystal microbalance (QCM) measurements determined that the mass change per cycle (MCPC) increased with temperature from −6.7 ng/(cm2 cycle) at 150°C to −11.2 ng/(cm2 cycle) at 250°C. These MCPC values correspond to etch rates from 0.070 Å/cycle at 150°C to 0.117 Å/cycle at 250°C. X-ray reflectivity analysis confirmed the linear removal of HfO2 and measured an HfO2 ALEt etch rate of 0.11 Å/cycle at 200°C. Fourier transform infrared (FTIR) spectroscopy measurements also observed HfO2 ALEt using the infrared absorbance of the Hf-O stretching vibration. FTIR analysis also revealed absorbance features consistent with HfF4 or HfFx surface species as a reaction intermediate. The HfO2 etching is believed to follow the reaction: HfO2 + 4Sn(acac)2 + 4HF → Hf(acac)4 + 4SnF(acac) + 2H2O. In the proposed reaction mechanism, Sn(acac)2 donates acac to the substrate to produce Hf(acac)4. HF allows SnF(acac) and H2O to leave as reaction products. The thermal ALEt of many other metal oxides, as well as metal nitrides, phosphides, sulfides and arsenides, should be possible by a similar mechanism.
Computer Modelling for Better Diagnosis and Therapy of Patients by Cardiac Resynchronisation Therapy (2015)

Mathematical or computer models have become increasingly popular in biomedical science. Although they are a simplification of reality, computer models are able to link a multitude of processes to each other. In the fields of cardiac physiology and cardiology, models can be used to describe the combined activity of all ion channels (electrical models) or contraction-related processes (mechanical models) in potentially millions of cardiac cells. Electromechanical models go one step further by coupling electrical and mechanical processes and incorporating mechano-electrical feedback. The field of cardiac computer modelling is making rapid progress due to advances in research and the ever-increasing calculation power of computers. Computer models have helped to provide better understanding of disease mechanisms and treatment. The ultimate goal will be to create patient-specific models using diagnostic measurements from the individual patient. This paper gives a brief overview of computer models in the field of cardiology and mentions some scientific achievements and clinical applications, especially in relation to cardiac resynchronisation therapy (CRT).
Frailty and cardiovascular outcomes in the National Health and Aging Trends Study (2021)

In patients without CHD, frailty is a risk factor for the development of MACEs. Efforts to identify frailty in patients without CHD and interventions to limit or reverse frailty status are needed and, if successful, may limit subsequent adverse cardiovascular events.
Dynamic Allocation of Computing and Communication Resources in Multi-Access Edge Computing for Mobile Users (2021)

The Multi-Access Edge Computing (MEC) constitutes computing over virtualized resources distributed at the edge of mobile network. For mobile users, an optimal allocation of communication and computing resources changes over time and space, and the resource allocation becomes a complex problem. Moreover, for delay constrained applications, the resource allocation to mobile users cannot be solved by approaches designed for static users, as a solution would not be obtained within a desired time. Thus, in this paper, we propose a low-complexity computing and communication resource allocation for offloading of real-time computing tasks generated with a high arrival rate by the mobile users. We exploit probabilistic modeling of the users’ movement to pre-allocate the computing resources at base stations and to select suitable communication paths between the users and the base station with the pre-allocated computing resources. The simulations show that the proposed algorithm keeps the offloading delay below 100 ms for the small tasks even with the arrival rate of five tasks per second per user, while the state-of-the-art algorithms can handle only up to 0.5 tasks per second per user. Thus, the proposal enables an exploitation of the MEC for various real-time applications even if the users are moving.
Recombinant Human Clara Cell Secretory Protein Treatment Increases Lung mRNA Expression of Surfactant Proteins and Vascular Endothelial Growth Factor in a Premature Lamb Model of Respiratory Distress Syndrome (2008)

Infant respiratory distress syndrome (IRDS) can lead to impaired alveolarization and dysmorphic vascularization of bronchopulmonary dysplasia. Clara cell secretory protein (CC10) has anti-inflammatory properties but is deficient in the premature infant. Because surfactant and vascular endothelial growth factor (VEGF) profiles are impaired by inflammation and CC10 inhibits lung inflammation, we hypothesized that CC10 may up-regulate surfactant protein (SP) and VEGF expression. Preterm lambs ( N = 24; 126 +/- 3 days [standard error] gestation) with IRDS were randomized to receive 100 mg/kg surfactant, 100 mg/kg surfactant followed by intratracheal 0.5, 1.5, or 5 mg/kg rhCC10 and studied for 4 hours. Gas exchange and lung mechanics were monitored; surfactant protein and VEGF mRNA profiles in lung were assessed. There was a significant rhCC10 dose-dependent increase in respiratory compliance and ventilation efficiency index; both parameters were significantly greater in animals treated with 5 mg/kg rhCC10 than those treated with surfactant alone. Similarly, there was a significant rhCC10 dose and protein-dependent increase in surfactant protein (SP-B > SP-C > SP-A) and dose- and isoform-dependent increase in VEGF (VEGF189 > VEGF165 > VEGF121). These data demonstrate that early intervention with rhCC10 up-regulates surfactant protein and VEGF expression, supporting the role of CC10 to protect against hyperoxia and mechanical ventilation in the immature lung.
Polymorphism of Angiotensin Converting Enzyme, Angiotensinogen, and Apolipoprotein E Genes in a Japanese Population With Cerebrovascular Disease (1997)

The homozygous deletion allele of the angiotensin converting enzyme gene (ACE/DD), homozygous threonine allele of the angiotensinogen gene (AGN/TT), and the epsilon4 allele of the apolipoprotein E gene (apoE/epsilon4) are reported to be associated with ischemic heart disease. Cerebrovascular disease (CVD) is another atherosclerotic disease; and the effects of these polymorphisms on CVD have been confusing. In this study, we investigated whether ACE/DD, AGN/TT, and apoE/epsilon4 genotypes are associated with CVD and whether genetic risk is enhanced by the effect of one upon another. We ascertained these genotypes in patients with cerebral infarction (n = 55) and cerebral hemorrhage (n = 38), diagnosed by brain computed tomography. Control subjects for the infarction group and the hemorrhage group were randomly selected from 583 subjects matched for age, gender, and history of hypertension with patients. Frequency of ACE/DD genotype was higher in the patients with infarction than in the controls (chi2 = 6.1, P < .05). The AGN/TT genotype was not associated with either infarction or hemorrhage, but it increased the relative risk for cerebral infarction in the subjects with ACE/DD genotype (chi2 = 8.0, P < .01, odds ratio; 11.7, 95% confidence intervals: 1.4 to 96.0). There was no significant association between apoE/epsilon4 and CVD. These results suggest that ACE/DD predicts cerebral infarction, but not cerebral hemorrhage, and that AGN/TT enhances the risk for cerebral infarction associated with ACE/DD.
Translocation and translaminar bioavailability of two neonicotinoid insecticides after foliar application to cabbage and cotton (2002)

A laboratory study was undertaken to investigate the leaf systemic properties and the translaminar aphicidal activity of two commercialised neonicotinoid (chloronicotinyl) insecticides. For that purpose [14C]imidacloprid was subjected to uptake and translocation studies in cabbage and cotton after foliar application. Foliar penetration and short-term translocation patterns of imidacloprid were similar in both plant species. Nevertheless imidacloprid penetrated twice as much into cabbage leaves as it did into cotton leaves. It showed a comparable translaminar behaviour and was entirely translocated acropetally, indicating its well-known xylem mobility. The translaminar and acropetal movement of imidacloprid and acetamiprid were quantified by simple laboratory bioassays using the green peach aphid, Myzus persicae (Sulzer), and the cotton aphid, Aphis gossypii (Glover), as typical homopteran pests for cabbage and cotton, respectively. A single dose (7.5 µg AI per leaf) applied to the upper leaf surface of cabbage and cotton was tested against aphids feeding on the lower leaf surface both close to and distant from the site of application 1, 5 and 12 days after treatment. The translaminar residual activity of imidacloprid on cabbage leaves was superior to that of acetamiprid, whereas its translaminar efficacy against A gossypii on cotton was inferior to that of acetamiprid. However, oral ingestion bioassays using an artificial double membrane feeding system revealed no significant differences in intrinsic activity between the two neonicotinoids tested. © 2001 Society of Chemical Industry
From Serendipity to Rational Antituberculosis Drug Discovery of Mefloquine-Isoxazole Carboxylic Acid Esters (2009)

Both in vitro and in vivo metabolism studies suggested that 5-(2,8-bis(trifluoromethyl)quinolin-4-yloxymethyl)isoxazole-3-carboxylic acid ethyl ester (compound 3) with previously reported antituberculosis activity is rapidly converted to two metabolites 3a and 3b. In order to improve the metabolic stability of this series, chemistry efforts were focused on the modification of the oxymethylene linker of compound 3 in the present study. Compound 9d with an alkene linker was found to be both more metabolically stable and more potent than compound 3, with a minimum inhibitory concentration (MIC) of 0.2 microM and 2.6 microM against replicating and nonreplicating Mycobaterium tuberculosis, respectively. These attributes make 9d an interesting lead compound. A number of modifications were made to the structure of 9d, and a series of active compounds were discovered. Although some neurotoxicity was observed at a high dosage, this new series was endowed with both improved in vitro anti-TB activity and metabolic stability in comparison to compound 3.
CF[sub 4]-Plasma-Induced Fluorine Passivation Effects on Poly-Si TFTs with High-κ Pr[sub 2]O[sub 3] Gate Dielectric (2007)

High-performance polycrystalline silicon thin-film transistors ( TFTs) integrating high-κ gate dielectric and fluorine-passivated film are demonstrated. High gate capacitance density and thin equivalent-oxide thickness provided by the high-κ gate dielectric have the advantage of increasing the driving current capability of the TFT device, but an undesirable off-state leakage current could be introduced from the high electric field near the drain side. Introducing fluorine atoms into films by employing a low-temperature plasma treatment can effectively passivate the trap states. With plasma treatment on film, the electrical characteristics of TFTs can be significantly improved, including a steeper subthreshold swing, smaller threshold voltage, higher field-effect mobility, and better on/off current ratio compared with that without plasma treatment. The maximum off-state leakage current of the fluorine-passivated TFT is more than one order of magnitude lower than that of the control TFT. Furthermore, the incorporation of fluorine atoms by plasma treatment also improves the reliability of TFTs against hot carrier stressing, which is due to the formation of stronger bonds in place of weak bonds in the channel and at the gate interface. Therefore, high-performance and high-reliability TFTs with gate dielectric and plasma treatment on film are suitable for active-matrix liquid crystal display application.
Synthesis of Tailored Segmented Polyurethanes Utilizing Continuous-Flow Reactors and Real-Time Process Monitoring (2021)

Conducting polymerizations under continuous-flow conditions affords distinct advantages over batch experimentation and has increasingly been employed by the research community for chain-growth polymerizations to accelerate material discovery and to finely tune material properties. This work now expands on the reported advances by demonstrating the utility of continuous flow for polyaddition reactions of polyurethanes (PUs). Various reactor configurations enable the on-demand organocatalytic one-step synthesis of linear PUs with tailored soft-to-hard segment ratios in 3–5 min at room temperature. In-line analytics is implemented for real-time process monitoring and to develop process control mechanisms, increasing the control over monomer conversion and material quality and minimizing batch-to-batch variations. The reported strategies thus provide a guideline for the straightforward preparation of libraries of commercially relevant PU materials.
Temperature and time dependence of B and P diffusion in Si during surface oxidation (1990)

Diffusion of B and P in silicon during surface oxidation in dry O2 has been measured as a function of time and temperature. The diffusion coefficients were measured for oxidations at 900, 1000, and 1100 °C for times ranging from 5 min to 4 h. For a 30-min oxidation at 900 °C, the measured P diffusion was 15 times greater than diffusion in an inert ambient. The diffusion enhancements for B and P decreased as the temperature was increased. Increasing oxidation times at a given temperature resulted in a decrease in the diffusion enhancement. The time and temperature dependence of the interstitial component of B and P diffusion are analyzed. By using P diffusion as an interstitial monitor, the fraction of boron diffusion which occurs through the interstitial mechanism is calculated to be 0.8 at 1100 °C.
Non-Linear Trajectory Optimization for Large Step-Ups: Application to the Humanoid Robot Atlas (2020)

Performing large step-ups is a challenging task for a humanoid robot. It requires the robot to perform motions at the limit of its reachable workspace while straining to move its body upon the obstacle. This paper presents a non-linear trajectory optimization method for generating step-up motions. We adopt a simplified model of the centroidal dynamics to generate feasible Center of Mass trajectories aimed at reducing the torques required for the step-up motion. The activation and deactivation of contacts at both feet are considered explicitly. The output of the planner is a Center of Mass trajectory plus an optimal duration for each walking phase. These desired values are stabilized by a whole-body controller that determines a set of desired joint torques. We experimentally demonstrate that by using trajectory optimization techniques, the maximum torque required to the full-size humanoid robot Atlas can be reduced up to 20% when performing a step-up motion.
Aluminum(2P)-silane complex and photoreversible oxidative addition/reductive elimination reaction Al(2P){SiH4} .tautm. SiH3AlH. 1. Al(2P){SiH4} complex (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAluminum(2P)-silane complex and photoreversible oxidative addition/reductive elimination reaction Al(2P){SiH4} .tautm. SiH3AlH. 1. Al(2P){SiH4} complexMichael A. Lefcourt and Geoffrey A. OzinCite this: J. Phys. Chem. 1991, 95, 7, 2616–2623Publication Date (Print):April 1, 1991Publication History Published online1 May 2002Published inissue 1 April 1991https://pubs.acs.org/doi/10.1021/j100160a002https://doi.org/10.1021/j100160a002research-articleACS PublicationsRequest reuse permissionsArticle Views83Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
ChemInform Abstract: Hexahydropyrrolo[2,3‐b]indoles: A New Class of Structurally Rigid Tricyclic Skeleton for Oxazaborolidine‐Catalyzed Asymmetric Borane Reduction. (2010)

Abstract A wide range of alcohols are available in excellent yields with good to high enantioselectivity.
Initial Access Optimization for Millimeter Wave Wireless Networks (2021)

The initial access in 5G New Radio (NR) standalone millimeter wave (mmWave) uses the techniques of beam sweeping to Figure out appropriate directions of transmission and reception. Beam sweeping refers to the transmission of cell specific signals by the base station (BS) while switching beam direction in a sequential manner in order to cover the whole cell. The conventional beam sweeping consists of transmitting sequentially and periodically the beams, according to a fixed pattern, which results in an initial access latency. The aim of this paper is to minimize the overall number of timeslots needed to connect all users to the BS by allowing using multiple beams in some slots and then activating the beams in a prioritized and controlled manner rather than sequentially and periodically as in the conventional scheme. The problem is formulated as a combinatorial optimization problem, for which a Semidefinite Relaxation-based (SDR-based) solving approach is proposed. Numerical results demonstrate that our scheme outperforms significantly the conventional beam sweeping.
Transistors on two-dimensional semiconductors: contact resistance limited by the contact edges (2017)

We report for the first time a TCAD investigation on the spatial distribution of carrier injection at MoS <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> contacts. The proposed semi-classical approach successfully captures the experimentally observed contact behavior. Using the model, we identify that for monolayer and bilayer MoS <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> , the carriers are injected at the edge of the contact metal, resulting in a high contact resistance. The primary cause of this high resistance is carrier depletion under the contacts, which is not alleviated at degenerate doping under the contacts.
Rotationally restricted mimics of rigid molecules: nonspirocyclic hydantoin aldose reductase inhibitors (1989)

Sorbinil (1), a spirocyclic hydantoin, is a potent inhibitor of the enzyme aldose reductase. Simulation of the rigid spirocyclic ring orientation found in sorbinil was achieved with nonspirocyclic 5-[5'-chloro-2'-(alkylsulfonyl)-phenyl]hydantoins and 5-[5'-chloro-2'-[(N-alkylamino)sulfonyl]phenyl]hydantoins. The 2'-substituent (SO2R) was sufficiently large to hinder rotation of the hydantoin ring, forcing an orientation similar to that of a spirocyclic hydantoin. Calculated conformational preference, X-ray data, and inhibitory IC50 values for these nonspirocyclic 2'-substituted (SO2R) phenylhydantoins are in accord with what is expected for spirocyclic hydantoins and comparable to those of sorbinil.
Loss of DJ‐1 protein stability and cytoprotective function by Parkinson's disease‐associated proline‐158 deletion (2012)

DJ-1 is a ubiquitous protein regulating cellular viability. Recessive mutations in the PARK7/DJ-1 gene are linked to Parkinson's disease (PD). Although the most dramatic L166P point mutation practically eliminates DJ-1 protein and function, the effects of other PD-linked mutations are subtler. Here, we investigated two recently described PD-associated DJ-1 point mutations, the A179T substitution and the P158Δ in-frame deletion. [A179T]DJ-1 protein was as stable as wild-type [wt]DJ-1, but the P158Δ mutant protein was less stable. In accord with the notion that dimer formation is essential for DJ-1 protein stability, [P158Δ]DJ-1 was impaired in dimer formation. Similar to our previous findings for [M26I]DJ-1, [P158Δ]DJ-1 bound aberrantly to apoptosis signal-regulating kinase 1. Thus, the PD-associated P158Δ mutation destabilizes DJ-1 protein and function. As there is also evidence for an involvement of DJ-1 in multiple system atrophy, a PD-related α-synucleinopathy characterized by oligodendroglial cytoplasmic inclusions, we studied an oligodendroglial cell line stably expressing α-synuclein. α-Synuclein aggregate dependent microtubule retraction upon co-transfection with tubulin polymerization-promoting protein p25α was ameliorated by [wt]DJ-1. In contrast, DJ-1 mutants including P158Δ failed to protect in this system, where we found evidence of apoptosis signal-regulating kinase 1 (ASK1) involvement. In conclusion, the P158Δ point mutation may contribute to neurodegeneration by protein destabilization and hence loss of DJ-1 function.