gebhart/patrepeval huggingface dataset:
Embedding Distributed Temperature and Strain Optical Fiber Sensors in Metal Components Using Additive Manufacturing (2018)

This paper demonstrates a fiber-sensor fused additive manufacturing process. Distributed fiber optical sensors were metalized through electroplating process and embedded in metal parts using a laser engineered net shaping process. Temperature and strain profiles were monitored in real-time with 5 mm spatial resolution.
Applied perspective on color difference measurement (1988)

Recent advances in electronic display and hard copy technology have made the use of full-color presentations feasible for a variety of applications. Color can enhance pictorial realism, increase human operator visual throughput, and facilitate performance in complex task environments. Realization of these benefits requires the specification of discriminable color sets and reliable tolerances on system visual parameters. The measurement and prediction of color differences are fundamental to these processes. This paper examines the use of existing measures of small color differences, such as CIELUV and CIELAB, for color specification problems for electronic visual displays. While small color difference formulas appear intuitively appropriate for specifying chromaticity tolerances for visual displays, their a priori applicability to large color difference problems such as color set selection would seem questionable. Nevertheless, small color difference formulas have been used for display color selection with considerable success. This success is manifest in consistent relationships between color difference estimates and a variety of visual performance measures, including color discrimination, color identification, reaction time, and visual search. Practical limitations of existing approaches to color difference measurement are discussed within the context of today’s complex color imaging devices and varied application environments.
Solution-Processable α,ω-Distyryl Oligothiophene Semiconductors with Enhanced Environmental Stability (2009)

We describe the rational design of oligothiophene semiconductors to facilitate solution-based fabrication of environmentally stable organic field-effect transistors (OFETs). Ultrathin films of α,ω-distyryl quaterthiophene (DS4T), pentathiophene (DS5T), and sexithiophene (DS6T) were prepared via solution processing to probe the effect of styryl end groups, oligomer length, and thin film structure on air stability. These films were prepared via solution deposition and thermal annealing of precursors featuring thermally labile ester solubilizing groups. A detailed study of the thin film structure was performed using atomic force microscopy (AFM), near-edge X-ray absorption fine structure (NEXAFS) spectroscopy, and grazing incidence X-ray diffraction (GIXD). Functional OFETs were obtained for DS5T and DS6T and have, respectively, hole mobilities of 0.051 and 0.043 cm2/(V s) and on/off ratios of 1 × 105 to 1 × 106, whereas DS4T OFETs failed to function because of poor film continuity. The effect of both short-term and long-term exposure to air is tracked in OFETs revealing remarkable stability for both DS5T and DS6T. This stability is attributed to the elimination of reactive sites in α,ω-distyryl oligothiophenes and suggests that careful choice of end-group structure can stabilize these molecules against oxidative degradation.
Effects of domain composition on catalytic activity of human UDP-glucose:glycoprotein glucosyltransferases (2016)

Uridine diphosphate (UDP)-glucose:glycoprotein glucosyltransferase (UGGT) 1 is a soluble protein residing in the endoplasmic reticulum (ER) and partially in ER-Golgi intermediate compartment. Characteristically, it is able to recognize incompletely folded proteins and re-glucosylate their high-mannose-type glycans. By virtue of this, UGGT1 acts as a folding sensor in the glycoprotein quality control system in the ER. On the other hand, human UGGT2 (HUGT2) has been believed to be an inactive homolog of human UGGT1 (HUGT1), whereas our recent study discovered its activity as UGGT. Although the activity of HUGT2 is significantly lower than HUGT1, C-terminal catalytic region, accounting for approximately 20% of the full-length enzyme, shares high amino acid sequence identity (>85%). In this study, we aimed to clarify the contribution of the noncatalytic domains by comparing activities of truncated forms of recombinant HUGT1/HUGT2 and HUGT1/HUGT2 chimeras with full-length enzymes. Our results obtained by using synthetic substrate indicate that the C-terminal catalytic regions of HUGTs are functional as UGGT. While the activity of HUGT1, but not that of HUGT2, was enhanced by the presence of N-terminal domains, activities of catalytic domains are similar between two homologs.
Global Patterns and Climatic Controls of Dust-Associated Microbial Communities (2021)

The ubiquity and long-range transport of the microorganisms inhabiting dust can pose a serious risk to human, animal, and plant health. The well-recognized importance of dust-associated microorganisms contrasts starkly with our limited understanding of the factors determining the variation in the composition of these communities at the global scale. Here, we provide the first insight into the global determinants of dust-associated microorganisms by quantifying the environmental factors shaping bacterial and fungal community composition in 467 outdoor settled dust samples collected from 33 countries and 6 continents. Our results show that the global variation in dust-associated bacterial and fungal community composition was, to some degree, predictable from mean annual precipitation and temperature. Notably, our results show that the fungal genera <i>Alternaria</i> and Aspergillus, which contain many species that can serve as triggers of allergenic disease in humans and as plant pathogens, were more abundant in drier regions. Collectively, these results highlight the key influence of climate on the global distribution of dust-associated microorganisms and provide the baseline information needed to build a more comprehensive understanding of how microbial exposures vary across the globe and in response to climate change. <b>IMPORTANCE</b> A broad diversity of microorganisms can be found in dust, with some of these microorganisms capable of causing allergenic disease in human via inhalation or affecting plant health by acting as plant pathogens. However, the spatial variation in dust microbiomes and the environmental factors associated with this variation have not been comprehensively assessed at the global scale. Here, we investigated the bacteria and fungi found in outdoor settled dust samples spanning 33 countries and 6 continents. Our results show that dust-associated bacteria and fungi exhibit climate-driven variability in community composition at the global scale. Our results call for the development of strategies to predict the geographic distribution of dust-associated microorganisms and to identify the potential associations between microbial exposures and the health of humans, animals, and plants.
A passive capacitive soil moisture and environment temperature UHF RFID based sensor for low cost agricultural applications (2017)

In this paper, we present the design, fabrication and calibration of a passive UHF RFID tag based soil moisture and environment temperature sensor. The inter-digital double-sided capacitive sensor developed modifies its capacitance as the soil moisture changes, due to modification of the soil permittivity. The implemented smart tag includes an external sensor front-end that is capable to process analog sensors and send digitized measurements to the reader. In order to obtain reliable readings, a process of calibration was performed and described. The used RFID chip also includes a built-in temperature sensor. The developed sensor tag presented a 6.95 ADC LSB variation per soil water content percentage and the capability to measure temperatures in a range of 0.3-59.6 °C with a 0.058°C resolution.
Multiple dynamic matching and median filters applied to sonic well logs (2010)

Nonlinear signal matching is a generalization of cross correlation in that a discrete lag between signals is replaced with a variable lag function or 'matching function', m(x). Two methods are reviewed which attempt to solve for m(x), namely the dynamic programming approach and the inverse theory approach. Both methods suffer from pitfalls and require the input of prior constraints to ensure convergence to the correct solution. The goal of this work has been to develop a method that can handle simple or complex matching problems and can succeed without any prior knowledge constraints. The multiple dynamic matching method is the result. It uses a significance threshold to extract a set of ridge points from a similarity matrix and applies dynamic programming to obtain a set of matched sections. These significant matched sections or 'subpaths' are then combined into a set of complete matching functions and a 'mean local confidence' norm is evaluated to determine the best overall match. It is argued through a model of change between signals, that given that the correct matching function is known, the presence of large amplitude changes between signals can cause the correct matching function to appear suboptimal under similarity norms. Multiple dynamic matching, because it generates suboptimal solutions as well, does not overlook the correct matching function. Typically the top three interpretations as ranked by mean local confidence will contain the expert's choice for the correct matching function. The use of median filters to preprocess the data and enhance well log features for matching has been investigated. A new 'median decomposition' is discussed as well, and in the context of a scale - space point of view to filtering, it is argued that median scale space is the proper choice for blocky waveforms. Finally, the connection between multiple dynamic matching and pattern recognition is explored, and matching iteratively through scale is proposed as a means of further generalizing the multiple dynamic matching method, making efficient high resolution matching possible.
Virtex-5 FXT a new FPGA platform, plus a look into the future (2008)

This article consists of a collection of slides from the author's conference presentation. Virtex-5 is the winner, without any real competition - Xilinx strategy of sub-families proved to be very successful Multi-gigabit transceivers are very popular Moore's Law will give us much more logic and lower cost - Speed and power consumption pose a difficult challenge Users want and need to improve design productivity - The pace is becoming faster and more competitive.
Brief announcement (2004)

This paper describes the Prefix Hash Tree, a distributed data structure that enables range queries over Distributed Hash Tables.
ChemInform Abstract: Improved Procedures for Large Scale Preparation of 6‐ and 7‐Oxy‐Substituted Isoquinolines and a Convenient Work‐Up Protocol for Titanium Supported Reactions. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Iridium Catalysts with Chiral Imidazole‐Phosphine Ligands for Asymmetric Hydrogenation of Vinyl Fluorides and other Olefins. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Room-Temperature Synthesis and Optical Properties of NdVO4 Nanoneedles (2018)

Tetragonal NdVO4 nanoneedles were prepared via a simple room-temperature precipitation method in the absence of any surfactant or template, starting from simple inorganic salts, NdCl3 and Na3VO4, as raw materials. The nanoneedles were characterized by XRPD, SEM, Raman, PL, and lifetime spectroscopy. The particles have a length of about 100 nm and a diameter of 20 nm and grow along <112> direction. The advantages of this method lie in the high yield, non-toxic solvents, mild reaction conditions, and that it can potentially be employed for the preparation of other 1D lanthanide vanadates.
Gibbs Max-Margin Topic Models with Fast Sampling Algorithms (2013)

Existing max-margin supervised topic models rely on an iterative procedure to solve multiple latent SVM subproblems with additional mean-field assumptions on the desired posterior distributions. This paper presents Gibbs max-margin topic models by minimizing an expected margin loss, an upper bound of the existing margin loss derived from an expected prediction rule. By introducing augmented variables, we develop simple and fast Gibbs sampling algorithms with no restricting assumptions and no need to solve SVM subproblems for both classification and regression. Empirical results demonstrate significant improvements on time efficiency. The classification performance is also significantly improved over competitors.
Imide‐aryl ether ketone block copolymers (1992)

Abstract Imide‐aryl ether ketone block copolymers were prepared and their morphology and thermal and mechanical properties investigated. Two aryl ether ketone blocks were incorporated; the first was an amorphous block derived from bisphenol–A and the second block was a semi‐crystalline poly(aryl ether ether ketone) prepared from a soluble and amorphous ketimine precursor. Bis(amino) aryl ether ketone and aryl ether ketimine oligomers were prepared via a nucleophilic aromaic substitution reaction with molecular weights ranging from 6,000 to 12,000 g/mol. The oligomers were co‐reacted with 4,4′‐oxydianiline (ODA) and pyromellitic dianhydride (PMDA) diethyl ester diacyl chloride in N ‐methyl–2‐pyrrolidone (NMP) in the presence of N ‐methylmorpholine. The copolymer compositions, determined by H‐NMR, of the resulting amic ester based copolymers ranged from 8 to 50 wt % aryl ether ketone or ketimine content. Prior to imide formation, the ketimine moiety of the aryl ether ketimine block was hydrolyzed ( p ‐toluene sulfonic acid) to the ketone form producing the aryl ether ether ketone block. Compositions of this block were maintained low to retain solubility. Solutions of the copolymers were cast and cured to effect imidization, producing clear films with high moduli (ca. 2200 MPa) and elongations (33–100%). The copolymers displayed good thermal stability with decomposition temperatures in excess of 450°C. Multiphase morphologies were observed irrespective of the co‐block type, block length or composition. © 1992 John Wiley &amp; Sons, Inc.
RTK-dependent inducible degradation of mutant PI3Kα drives GDC-0077 (Inavolisib) efficacy (2021)

Abstract PIK3CA is one of the most frequently mutated oncogenes; the p110α protein it encodes plays a central role in tumor cell proliferation and survival. Small molecule inhibitors targeting the PI3K p110α catalytic subunit have entered clinical trials, with early-phase GDC-0077 (Inavolisib) studies showing anti-tumor activity and a manageable safety profile in patients with PIK3CA -mutant, hormone receptor-positive breast cancer as a single agent or in combination therapy. Despite this, preclinical studies have shown that PI3K pathway inhibition releases negative feedback and activates receptor tyrosine kinase signaling, reengaging the pathway and attenuating drug activity. Here we discover that GDC-0077 and taselisib more potently inhibit mutant PI3K pathway signaling and cell viability through unique HER2-dependent degradation. Both are more effective than other PI3K inhibitors at maintaining prolonged pathway suppression, resulting in enhanced apoptosis and greater efficacy. This unique mechanism against mutant p110α reveals a new strategy for creating inhibitors that specifically target mutant tumors with selective degradation of the mutant oncoprotein and also provide a strong rationale for pursuing PI3Kα degraders in patients with HER2-positive breast cancer.
The POLYPHEM Project: An Innovative Small-Scale Solar Thermal Combined Cycle (2019)

The POLYPHEM project is a research and innovation action funded by the European Union's H2020 program.\nThe project started in April 2018 and will end in March 2022. It is implemented by a European consortium of 4 research centers and 5 industrial partners. The aim of this project is both to increase the flexibility and improve the performance of small solar tower power plants. The POLYPHEM concept consists in implementing a combined cycle formed by a solarized micro gas-turbine and a Rankine organic cycle machine, with an integrated thermal storage device between the two cycles.\nThe need for cooling is minimal. Developed from a technology already patented by CNRS and CEA, the pressurized air solar receiver is integrated in the micro-turbine cycle. The thermal efficiency targeted for the receiver is 80% with a cost of 400 €/kW. The innovative thermal storage uses thermal oil and a single thermocline tank with a technical concrete filler material. The main expected impact of this project is to enhance the competitiveness of low-carbon energy production systems through the technology developed. The expected progress is a better fitting of electricity generation to variable local needs and an overall conversion efficiency of solar energy into electricity of 18% for an investment cost of less than 5 €/W with low environmental impact. By 2030, the cost of electricity production targeted by the POLYPHEM technology is 165 €/MWh for an annual direct normal irradiation of 2600 kWh/m2/year (North Africa and Middle East) and 209 €/MWh under 2050 kWh/m2/year (Southern Europe). In addition to decentralized power generation, other applications are considered for the deployment of this technology used in poly-generation: industrial heat production, solar heating and cooling, desalination of seawater or brackish water. A prototype plant of 60 kWel with a thermal storage of 1300 kWh is designed, built and installed on the site of the experimental solar tower of Themis in Targasonne (France). The objective of the project is to validate the technical choices under test conditions representative of actual operating conditions.
BodyMap: A Collection of 3' ESTs for Analysis of Human Gene Expression Information (2000)

BodyMap is a collection of site-directed 3' expressed sequence tags (ESTs) (gene signatures, GSs) that contains the transcript compositions of various human tissues and was the first systematic effort to acquire gene expression data. For the construction of BodyMap, cDNA libraries were made, preserving abundance information and histologic resolutions of tissue mRNAs. By sequencing 164,000 randomly selected clones, 88,587 GSs that represent chromosomally coded transcripts have been collected from 51 human organs and tissues. They were clustered into 18,722 independent 3' termini from transcripts, and more than 3000 of these were not found among ESTs assembled in UniGene (Build 75). Assessment of the prevalence of polyadenylation signals and comparison with GenBank cDNAs indicated that there was no significant contamination by internally primed cDNAs or genomic fragments but that there was a relatively high incidence (12%) of alternative polyadenylation sites. We evaluated the sensitivity and resolution of expression information in BodyMap by in silico Northern hybridization and selection of tissue-specific gene probes. BodyMap is a unique resource for estimation of the absolute abundance of transcripts and selection of gene probes for efficient hybridization-based gene expression profiling.
Recent Development: Single Contact Optical Beam Induced Currents (SCOBIC) – Technique and Applications (2001)

Abstract Single contact optical beam induced currents (SCOBIC) is a variation on the OBIC failure analysis technique that requires only one point of contact with the junction being examined. This article discusses the basic principles of this new method and how it compares with OBIC in terms of measurement performance. It also presents examples showing how SCOBIC can be used to analyze CMOS devices from the front and back side without need for complex FIB and microprobing procedures.
Tartrate Resistant Acid Phosphatase Assisted Degradation of Single-Wall Carbon Nanotubes (SWCNTs) (2016)

In this study, we explored the capability of tartrate resistant acid phosphatase (TRAcP), a bone resorption marker, to degrade carboxylated single-walled carbon nanotubes (C-SWCNTs). Optical observations and Raman and high-resolution transmission electron microscopy studies show that the enzyme contributes to the degradation of C-SWCNTs, although the degradation is not complete. Molecular modeling implemented to investigate the binding sites for carboxylated and pristine SWCNTs to TRAcP elucidate the varying proximity of SWCNTs to the binuclear iron active site and the active site residues of TRAcP, which is clearly dependent upon the degree of carboxylation introduced into the SWCNT model. The modeling results presented provide justification to the propensity of TRAcP to degrade the C-SWCNTs alluding to the possibility of C-SWCNTs to be used as a potential degradable biomaterial for use in therapeutic applications of mineralized tissue related conditions.
Finite element simulations of interdigital electrode structures on high permittivity thin films (2001)

Abstract A finite element model (FEM) was developed for the simulation of the dielectric properties of high permittivity dielectric thin films on insulating substrates contacted by interdigital electrode (IDE) structures. From the simulations of electrical potentialand field distributions normalized capacitance values were extracted for various geometries and a wide range of film permittivities. The simulated data are compared with results obtained from the empirical formula of Farnell [1]. The FEM simulations were applied to experimental data of SrTiO3, BaTiO3 and Ba0.5Sr0.5TiO3 thin films on sapphire substrates contacted with different IDE structures.
Molecular mimicry between bacterial and self antigen in a patient with systemic lupus erythematosus (1999)

The importance of microbial infection as a trigger for the induction of systemic lupus erythematosus is frequently debated. Clinical observations indicate that anti-viral and antibacterial responses are often accompanied by self reactivity, and anti-pneumococcal antibodies elicited in non-autoimmune individuals by pneumococcal vaccine express lupus-associated anti-DNA idiotypes. To explore the relationship between protective and pathogenic antibodies in humans, we have used the phage display immunoglobulin expression system to generate a combinatorial library from spleen cells of a lupus patient immunized with a polyvalent pneumococcal polysaccharide vaccine prior to splenectomy. From this library, monovalent antigen-binding fragments expressing the 3I Vkappa1-associated idiotype were isolated. This idiotype is expressed on up to 90% of anti-DNA antibodies in the serum of lupus patients and on anti-pneumococcal antibodies in the serum of non-autoimmune individuals. Eight 3I+ monovalent antigen-binding fragments reacting with pneumococcal polysaccharide, DNA or both were analyzed. Four of these fragments were cross-reactive with both foreign and self antigen, demonstrating that a high percentage of anti-bacterial antibodies produced in a patient with lupus bind double-stranded DNA. These studies provide support at the molecular level for a potential role of molecular mimicry in the generation of anti-DNA antibodies. In addition, this is, to our knowledge, the first panel of fully sequenced human anti-pneumococcal antibodies.