gebhart/patrepeval huggingface dataset:
Silica Restricting the Sulfur Volatilization of Nickel Sulfide for High‐Performance Lithium‐Ion Batteries (2019)

Abstract Nickel sulfides are regarded as promising anode materials for advanced rechargeable lithium‐ion batteries due to their high theoretical capacity. However, capacity fade arising from significant volume changes during operation greatly limits their practical applications. Herein, confined NiS x @C yolk–shell microboxes are constructed to address volume changes and confine the active material in the internal void space. Having benefited from the yolk–shell structure design, the prepared NiS x @C yolk–shell microboxes display excellent electrochemical performance in lithium‐ion batteries. Particularly, it delivers impressive cycle stability (460 mAh g −1 after 2000 cycles at 1 A g −1 ) and superior rate performance (225 mAh g −1 at 20 A g −1 ). Furthermore, the lithium storage mechanism is ascertained with in situ synchrotron high‐energy X‐ray diffractions and in situ electrochemical impedance spectra. This unique confined yolk–shell structure may open up new strategies to create other advanced electrode materials for high performance electrochemical storage systems.
Safe memory reclamation for dynamic lock-free objects using atomic reads and writes (2002)

A major obstacle to the wide use of lock-free data structures, despite their many performance and reliability advantages, is the absence of a practical lock-free method for reclaiming the memory of dynamic nodes removed from dynamic lock-free objects for arbitrary reuse.The only prior lock-free memory reclamation method depends on the DCAS atomic primitive, which is not supported on any current processor architecture. Other memory management methods are blocking, require special operating system support, or do not allow arbitrary memory reuse.This paper presents the first lock-free memory management method for dynamic lock-free objects that allows arbitrary memory reuse, and does not require special operating system or hardware support. It guarantees an upper bound on the number of removed nodes not yet freed at any time, regardless of thread failures and delays. Furthermore, it is wait-free, it is only logarithmically contention-sensitive, and it uses only atomic reads and writes for its operations. In addition, it can be used to prevent the ABA problem for pointers to dynamic nodes in most algorithms, without requiring extra space per pointer or per node.
Dynamics of Polymers in Organosilicate Nanocomposites (2003)

Dynamic secondary ion mass spectrometry (DSIMS) measurements were performed to measure the effects of functionlized organosilicate clay (Cloisite 6A) on the tracer diffusion coefficient, D, in polystyrene (PS) and poly(methyl methacrylate) (PMMA) matrices. The results indicate that D is unaffected by the addition of 5% (by volume) of PS and is reduced by a factor of 3 with the addition of the same volume fraction in a PMMA matrix. The same ratio was also obtained for the extrapolated zero shear rate viscosity of PS and PMMA melt-mixed composites with the same volume fraction of clay. DSIMS was also used to measure the mobility of the clay platelets, which was found to be much lower than the polymer chains in both matrices. Examination of the sample morphology with scanning force and transmission electron microscopy indicated that in contrast to melt mixing, spin casting produced a large degree of exfoliation in both PS and PMMA matrices. Hence the difference in the dynamics in the presence of clay was ascribed to preferential interactions between the PMMA polymer and the platelet surface, rather than the extent of exfoliation.
Design of Dual-Polarization Horn-Coupled Kinetic Inductance Detectors\n for Cosmic Microwave Background Polarimetry (2015)

Mapping the polarization of the Cosmic Microwave Background is yielding\nexciting data on the origin of the universe, the reionization of the universe,\nand the growth of cosmic structure. Kilopixel arrays represent the current\nstate of the art, but advances in detector technology are needed to enable the\nlarger detector arrays needed for future measurements. Here we present a design\nfor single-band dual-polarization Kinetic Inductance Detectors (KIDs) at 20%\nbandwidths centered at 145, 220, and 280 GHz. The detection and readout system\nis nearly identical to the successful photon-noise-limited aluminum\nLumped-Element KIDs that have been recently built and tested by some of the\nauthors. Fabricating large focal plane arrays of the feed horns and\nquarter-wave backshorts requires only conventional precision machining. Since\nthe detectors and readout lines consist only of a single patterned aluminum\nlayer on a SOI wafer, arrays of the detectors can be built commercially or at a\nstandard university cleanroom.\n
Leishmanicidal and trypanocidal activity of extracts and secondary metabolites from basidiomycetes (1997)

Seventeen extracts and seven secondary metabolites isolated from basidiomycetes were tested in medium culture against promastigote forms of Leishmania spp. and bloodstream forms of Trypanosoma cruzi. Extracts from the culture filtrate or mycelium were generally inactive against the parasites except the Zucoagaricus genus mycelium extract which reduced by 47% the number of bloodstream forms. Striatin A, striatin B and podoscyphic acid exhibited in vitro activity at 10, 5 and 100 μg/mL, respectively. One compound showed activity against bloodstream forms of T. cruzi, the sesquiterpenoid naematolin, lysing the parasites by 79%. BALB/c mice infected with L. amazonensis were treated 3 weeks post-infection with striatin A and striatin B by subcutaneous route for 15 days at 10 mg/kg daily. The reference drug, N-methylglucamine antimonate, administered by subcutaneous injections at 28 mg Sbv/kg/day for 15 days reduced the parasite burden by 71.2% (p <0.05). Subcutaneous administration of straitin A at 10 mg/kg produced a weak decrease of the parasite burdens in the footpad by 17.6%. The treatment with striatin B had no effect and showed higher toxicity than striatin A. © 1997 John Wiley & Sons, Ltd.
All-optical address recognition for optically-asisisted routing in next-generation optical networks (2003)

Optical fiber communication technology enabled high-speed, long-distance capacity in today's networks. The packet switching functions such as address recognition and routing are performed in the electrical domain after optical-to-electrical conversion. As more real-time applications come online, demand for bandwidth increases, and electronic processing may potentially become a bottleneck at the intermediate nodes along the network. We introduce some optical address recognition schemes for optically-assisted routing that may decrease the processing delay at these nodes.
Single-cell quantification of functional outcomes of CD16 ligation in NK cells by Fc-engineered antibodies (2013)

Meeting abstracts Humanized monoclonal antibodies (mAb) targeting tumor antigens have paved the way to complementary strategies in the treatment of cancer by harnessing the immune system towards a more specific response against tumors. Such mAb can mobilize natural killer (NK) cells function by
Bastadin 6, a spongean brominated tyrosine derivative, inhibits tumor angiogenesis by inducing selective apoptosis to endothelial cells (2006)

Bastadin 6, a macrocyclic tetramer of a brominated tyrosine derivative, was isolated from a marine sponge and its anti-angiogenic activity was evaluated. Bastadin 6 was found to inhibit vascular endothelial growth factor (VEGF)- or basic fibroblast growth factor (bFGF)-dependent proliferation (IC50=0.052 micromol/l) of human umbilical vein endothelial cells (HUVECs) 20- to 100-fold selectively in comparison with normal fibroblast (3Y1) or several tumor cells (KB3-1, K562 and Neuro2A). Bastadin 6 also inhibited VEGF- or bFGF-induced tubular formation (0.1 micromol/l, 6 h treatment) and VEGF-induced migration (1 micromol/l, 4 h treatment) of HUVECs. Moreover, bastadin 6 almost completely blocked VEGF- or bFGF-induced in vivo neovascularization in the mice corneal assay and suppressed growth of s.c. inoculated A431 solid tumor in nude mice (100 mg/kg, i.p.). Bastadin 6 induced cell death of HUVECs with an apoptotic phenotype, whereas it showed no effect on the VEGF-induced auto-phosphorylation of VEGF receptors Flt-1 and KDR/Flk-1. These results suggest that the anti-angiogenic effect of bastadin 6 is closely related to selective induction activity of apoptosis against endothelial cells.
Superhydrophobic Breakdown of Nanostructured Surfaces Characterized in Situ Using ATR–FTIR (2017)

In situ characterization of the underwater stability of superhydrophobic micro- and nanostructured surfaces is important for the development of self-cleaning and antifouling materials. In this work, we demonstrate a novel attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy-based method for large-area wetting characterization of silicon nanopillars. When air is present in between the structures, as is characteristic of the Cassie-Baxter state, the relative intensities of the water bands in the absorption spectrum change because of the wavelength-dependent attenuation of the evanescent wave. This phenomenon enables unambiguous identification of the wetting state and assessment of liquid impalement. Using mixtures of isopropanol and water with different concentrations, the breakdown of superhydrophobic states and the wetting hysteresis effects are systematically studied on uniform arrays of silicon nanopillars. A transition from the Cassie-Baxter to Wenzel state is observed when the isopropanol concentration exceeds 2.8 mol %, corresponding to a critical surface tension of 39 mN/m. Spontaneous dewetting does not occur upon decreasing the isopropanol concentration, and pure water can be obtained in a stable Wenzel state on the originally superhydrophobic substrates. The developed ATR-FTIR method can be promising for real-time monitoring of the wetting kinetics on nanostructured surfaces.
Design and Characterization of a Bearingless Cross-Flow Fan (2021)

This paper presents a high-speed bearingless cross-flow fan particularly suited for applications in chemically demanding environments. In general, bearingless motors convince with a friction-and wear-free operation, unlimited lifetime and a hermetically-sealed encapsulation of the rotor. For the proposed cross-flow fan, a double-sided use of such motors additionally leads to twice the available torque for the blade rotation as well as a highly compact and safe system design. In sophisticated applications (e.g. gas-circulation systems of excimer laser) those arguments are crucial. After a description of the motor topolopy, the novel bearingless cross-flow fan prototype is introduced. To characterize its performance, measurements are performed on a ISO 5801 based test rig.
ChemInform Abstract: Asymmetric Radical‐Radical Cross‐Coupling Through Visible‐Light‐Activated Iridium Catalysis. (2016)

Abstract A visible light‐driven synthesis of 1,2 amino alcohols with high enantioselectivities (up to 99% e.e.) is presented by using a unique catalytic asymmetric process which combines a single electron transfer reaction between a donor substrate and a catalyst‐bound acceptor substrate followed by a stereocontrolled radical—radical recombination.
Alternative Splicing of Caspase 9 Is Modulated by the Phosphoinositide 3-Kinase/Akt Pathway via Phosphorylation of SRp30a (2010)

Increasing evidence points to the functional importance of alternative splice variations in cancer pathophysiology. Two splice variants are derived from the CASP9 gene via the inclusion (Casp9a) or exclusion (Casp9b) of a four-exon cassette. Here we show that alternative splicing of Casp9 is dysregulated in non-small cell lung cancers (NSCLC) regardless of their pathologic classification. Based on these findings we hypothesized that survival pathways activated by oncogenic mutation regulated this mechanism. In contrast to K-RasV12 expression, epidermal growth factor receptor (EGFR) overexpression or mutation dramatically lowered the Casp9a/9b splice isoform ratio. Moreover, Casp9b downregulation blocked the ability of EGFR mutations to induce anchorage-independent growth. Furthermore, Casp9b expression blocked inhibition of clonogenic colony formation by erlotinib. Interrogation of oncogenic signaling pathways showed that inhibition of phosphoinositide 3-kinase or Akt dramatically increased the Casp9a/9b ratio in NSCLC cells. Finally, Akt was found to mediate exclusion of the exon 3,4,5,6 cassette of Casp9 via the phosphorylation state of the RNA splicing factor SRp30a via serines 199, 201, 227, and 234. Taken together, our findings show that oncogenic factors activating the phosphoinositide 3-kinase/Akt pathway can regulate alternative splicing of Casp9 via a coordinated mechanism involving the phosphorylation of SRp30a.
Imaging of Primary Brain Tumors and Metastases with Fast Quantitative 3‐Dimensional Magnetization Transfer (2015)

MTR and qMT imaging enables a better differentiation between brain tumors and provides additive information to MRI.
Effects of High-Pressure Treatment on Spores of Clostridium Species (2016)

Spores of various clostridial organisms cause human disease, sometimes due to food contamination by spores. Because of these spores' resistance to normal decontamination regimens, there is continued interest in ways to kill spores without compromising food quality. High hydrostatic pressure (HP) under appropriate conditions can inactivate bacterial spores. With growing use of HP for food pasteurization, advancement of HP for commercial production of sterile low-acid foods requires understanding of mechanisms of spores' interactions with HP. While much is known about HP germination and inactivation of spores of Bacillus species, how HP germinates and inactivates clostridial spores is less well understood. In this work we have tried to remedy this information deficit by examining germination of spores of Clostridium difficile and Clostridium perfringens by several HP and temperature levels. The results may give insight that could facilitate more efficient methods for spore eradication in food sterilization or pasteurization, biodecontamination, and health care.
Fourth-generation Wireless Networks: Applications and Innovations (2009)

"This book presents a comprehensive collection of recent findings in access technologies useful in the architecture of wireless networks" - Provided by publisher
Sensitive Wavelength Dependence of PdC and Pd Formation from Photolysis of Bis(hexafluoroacetylacetonato)palladium(II) [J. Am. Chem. Soc. 2000, 122, 1227−1228]. (2000)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionSensitive Wavelength Dependence of PdC and Pd Formation from Photolysis of Bis(hexafluoroacetylacetonato)palladium(II) [J. Am. Chem. Soc.2000, 122, 1227−1228].Peter Muraoka, Daniel Byun, and Jeffrey I. ZinkCite this: J. Am. Chem. Soc. 2000, 122, 23, 5670Publication Date (Web):May 27, 2000Publication History Published online27 May 2000Published inissue 1 June 2000https://pubs.acs.org/doi/10.1021/ja004649fhttps://doi.org/10.1021/ja004649fcorrectionACS PublicationsCopyright © 2000 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views290Altmetric-Citations2LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (10 KB) Get e-Alertsclose Get e-Alerts
A flexible parylene probe for in vivo recordings from multiple subregions of the rat hippocampus (2016)

The hippocampus is crucial to the formation of long-term memory and declarative memory. It is divided into three sub-fields the CA1, the CA3 and the DG. To understand the neuronal circuitry within the hippocampus and to study the role of the hippocampus in memory function requires the collection of neural activities from multiple subregions of the hippocampus simultaneously. Micro-wire electrode arrays are commonly used as an interface with neural systems. However, recording from multiple deep brain regions with curved anatomical structures such as the thin cell body layers of the hippocampus requires the micro-wires to be arranged into a highly accurate, complex layout that is difficult to fabricated manually. In this work, we designed and developed a flexible parylene-C based neural probe which can be easily micro-machined to the desired dimensions. Sixty-four electrical recording sites are micromachined on to 8 parylene shanks and spaced according to the distribution of hippocampal principal neurons in different hippocampus subregions. Together with our collaborators, we developed and optimized the implantation procedure of the flexible parylene probe and tested the insertion method both in brain tissue phantom and in vivo with a sham device. Immunohistochemistry (IHC) staining post-implantation of the sham probe was used to verify the location of the probe and to evaluate immune responses to the probe. Fully functional devices were fabricated and, in future studies, functional probes will be chronically implanted into the rat hippocampus, and neural activities will be recorded and compared with signals obtained with micro-wire arrays.
Prosthetic joint infection due to Mycobacterium tuberculosis: a case series and review of the literature. (1998)

Prosthetic joint replacement is being performed more frequently for patients with prior septic arthritis due to Mycobacterium tuberculosis. Prosthetic joint infection due to Mycobacterium tuberculosis does occur, but is rare. We report the clinical characteristics and outcome of seven cases of Mycobacterium tuberculosis prosthetic joint infection seen at our institution over a 22-year period and summarize the English-language literature regarding current prophylaxis and treatment strategies. Tuberculous prosthetic joint infection most often represents reactivation of prior tuberculous septic arthritis. The diagnosis of tuberculous prosthetic joint disease is often delayed, because a history of prior Mycobacterium tuberculosis septic arthritis is not known. Treatment of tuberculous prosthetic joint infection requires a combined medical and surgical approach. Removal of the prosthesis has been the traditional surgical modality, followed by appropriate antituberculous therapy, but other surgical methods have been used successfully in selected cases. To decrease the risk of reactivation of infection after prosthesis implantation in patients with quiescent tuberculous septic arthritis who have not received prior antituberculous therapy, consideration should be given to preoperative or perioperative antituberculous prophylaxis.
Exploring compiler optimization opportunities for the OpenMP 4.x accelerator model on a POWER8+GPU platform (2016)

While GPUs are increasingly popular for high-performance computing, optimizing the performance of GPU programs is a time-consuming and non-trivial process in general. This complexity stems from the low abstraction level of standard GPU programming models such as CUDA and OpenCL: programmers are required to orchestrate low-level operations in order to exploit the full capability of GPUs. In terms of software productivity and portability, a more attractive approach would be to facilitate GPU programming by providing high-level abstractions for expressing parallel algorithms.OpenMP is a directive-based shared memory parallel programming model and has been widely used for many years. From OpenMP 4.0 onwards, GPU platforms are supported by extending OpenMP's high-level parallel abstractions with accelerator programming. This extension allows programmers to write GPU programs in standard C/C++ or Fortran languages, without exposing too many details of GPU architectures.However, such high-level parallel programming strategies generally impose additional program optimizations on compilers, which could result in lower performance than fully hand-tuned code with low-level programming models. To study potential performance improvements by compiling and optimizing high-level GPU programs, in this paper, we 1) evaluate a set of OpenMP 4.× benchmarks on an IBM POWER8 and NVIDIA Tesla GPU platform and 2) conduct a comparable performance analysis among hand-written CUDA and automatically-generated GPU programs by the IBM XL and clang/LLVM compilers.
Synthesis of 6-Acetamido-5-amino- and -5-guanidino-3,4-dehydro-N-(2-ethylbutyryl)- 3-piperidinecarboxylic Acids Related to Zanamivir and Oseltamivir, Inhibitors of Influenza Virus Neuraminidases (2000)

[reaction: see text] 6-Acetamido-5-amino- and -5-guanidino-3, 4-dehydro-N-(2-ethylbutyryl)-3-piperidinecarboxylic acids (8 and 9) have been synthesized starting from natural siastatin B, a bacterial neuraminidase inhibitor isolated from Streptomyces culture in a stereospecific fashion. These compounds are related to zanamivir and oseltamivir, inhibitors of influenza virus neuraminidases.
Performance Bounds and Design Criteria for Estimating Finite Rate of Innovation Signals (2012)

In this paper, we consider the problem of estimating finite rate of innovation (FRI) signals from noisy measurements, and specifically analyze the interaction between FRI techniques and the underlying sampling methods. We first obtain a fundamental limit on the estimation accuracy attainable regardless of the sampling method. Next, we provide a bound on the performance achievable using any specific sampling approach. Essential differences between the noisy and noise-free cases arise from this analysis. In particular, we identify settings in which noise-free recovery techniques deteriorate substantially under slight noise levels, thus quantifying the numerical instability inherent in such methods. This instability, which is only present in some families of FRI signals, is shown to be related to a specific type of structure, which can be characterized by viewing the signal model as a union of subspaces. Finally, we develop a methodology for choosing the optimal sampling kernels for linear reconstruction, based on a generalization of the Karhunen-Loève transform. The results are illustrated for several types of time-delay estimation problems.