gebhart/patrepeval huggingface dataset:
Role of Molecular Architecture on Ion Transport in Ethylene oxide-Based Polymer Electrolytes (2021)

This work aims to develop a detailed mechanistic understanding of the role of a graft polymer architecture on lithium ion (Li+) transport in poly(ethylene oxide)-based polymer electrolytes. Specifically, we compare Li+ transport in poly(ethylene oxide) (PEO) versus poly(oligo oxyethylene methacrylate) (POEM) polymers doped with lithium bis(trifluoromethanesulfonyl) (LiTFSI) salts, using both experimental electrochemical characterization and molecular dynamics (MD) simulations. Our results indicate that POEM exhibits a range of relaxation processes that cannot be interpreted solely in terms of glass-transition temperature (Tg) effects. Due to its side-chain architecture, the segmental relaxation of POEM is nonuniform across ether oxygens (EOs) and shows a more pronounced sensitivity to temperature above Tg compared to PEO. Moreover, POEM also exhibits a nonuniform Li+ coordination behavior, in which Li+ is primarily solvated by two different chains in POEM, compared to a single chain in PEO. Li+ transport in POEM occurs via two events with distinct characteristic times: a fast intrachain hopping along side chains and a slow interchain hopping between side chains. Taken together, the relaxation processes and ion transport mechanisms identified in POEM provide useful insights into design of more effective solid polymer electrolytes.
Silicon Photonic Electric Field Sensor Based on Electro-Optical Effect and Micro-Ring Resonator (2021)

Advanced electric field sensing and measurement technology are one of the important technical bases of the smart grid. In this paper, the basic principle and fabrication method of integrated optical waveguide electric field sensor based on electro-optic effect and the micro-ring resonator are presented. The refractive index of the electro-optic polymer film is changed under the electric field, which leads to the change of effective refractive index of the optical waveguide, and the electric field sensing can be realized by monitoring the shift of the silicon micro-ring resonant wavelength. Then, the theoretical and experimental results show that the shift in the micro-ring resonant wavelength of the sensor is directly proportional to the electric field amplitude, when the measured electric field amplitude is from -25kV/cm to 25 kV/cm. This paper can provide a theoretical basis for the miniaturization of electric field sensors and promote the development of silicon-based photoelectric sensors.
A high power EMI sensor for detecting and classifying small and deep targets (2016)

Detecting and classifying small (i.e., with calibers ranging from 20 to 60 mm) and deep targets (burial depth more than 11 times targets diameter) is still a challenging problem using current advanced EMI sensors and signal processing approaches. In order to overcome this problem, the standard time-domain NRL TEMTADS 2x2 electromagnetic induction (EMI) instrument is updated. Namely, the NRL TEMTADS 2x2 system’s transmitter electronics is modified to increase transmitter (Tx) currents from 6 Amperes to 14 Amperes. The instrument has a Tx array with four coplanar square coils, together with four tri-axial receivers (Rx) placed at the center of each Tx. Each Rx cube contains three orthogonal coils and thus registers all three vector components of the impinging signals. The Tx coils, with transmitter currents of ~14 A, illuminate a buried target, and the target responses are collected with a 500 kHz sample rate after turn off of the excitation pulse. The system operates in both static (cued) and dynamic modes. For cued mode, the raw decay measurements are grouped into 121 logarithmically-spaced “gates” whose center times range from 25 &mu;s to 24.35 ms with 5% widths. The sensor is placed on a cart which provides a sensor-to-ground offset of 20 cm or less. In this paper, studies for APG Calibration, Blind, and Small Munitions Grids are presented and analyzed. The areas are arranged in grids of test cells and the cell center positions are known. Each target position is flagged with a non-metallic pin flag using cm-level GPS. The sensor is positioned over each target in turn. With the system positioned over the target, each Tx is activated sequentially and during off the Tx current, all four Rx record data. The capabilities of this sensor platform is rigorously investigated for UXO classification at APG blind and small munitions grids.
Challenges in Histologic Diagnosis of Nonchordomatous Lesions of the Clivus (2015)

Challenges can occur in the radiologic evaluation and pathologic differentiation of diverse bone lesions with overlapping morphologic features as well as in the differentiation between neoplastic, reactive, inflammatory, and metabolic bone lesions and developmental disorders. Despite more than 1 biopsy, histologic classification will not always lead to a definitive diagnosis. In such cases, an interdisciplinary team should decide whether additional biopsies should be performed or whether clinical, endoscopic, and radiologic controls are sufficient.
Characterization of Zinc Oxide Films Grown by a Newly Developed Plasma Enhanced Metal Organic Chemical Vapor Deposition Employing Microwave Excited High Density Plasma (2008)

The radical reaction based semiconductor manufacturing has been applied to silicon device process. Such as SiO2 and Si3N4 can be formed at low temperatures of under 500–600 °C. In this study, we applied radical reaction based semiconductor manufacturing to compound semiconductor of ZnO. The characteristics of ZnO films grown by a newly developed plasma enhanced metal organic chemical vapor deposition (MOCVD) employing microwave excited high-density plasma are good. The film formed on a-plane sapphire is epitaxially oriented in c-axis direction, and the composition is similar to ZnO substrate grown by hydrothermal method. The mobility of grown film at around 400 °C is 23 cm2/(V·s), and it is increased to 46 cm2/(V·s) by 700 °C annealing. The carbon concentration in the films can be reduced by the selection of a zinc precursor and the optimization of process conditions. The active species of plasma are effective for the crystallization of films.
Deficiency of iPLA2β Primes Immune Cells for Proinflammation: Potential Involvement in Age-Related Mesenteric Lymph Node Lymphoma (2015)

Proinflammation can predispose the body to autoimmunity and cancer. We have reported that iPLA₂β(-/-) mice are susceptible to autoimmune hepatitis and colitis. Here we determined whether cytokine release by immune cells could be affected by iPLA₂β deficiency alone or combined with CD95/FasL-antibody treatment in vivo. We also determined whether cancer risk could be increased in aged mutant mice. Immune cells were isolated from 3-month old male WT and iPLA₂β(-/-) mice, and some were injected with anti-CD95/FasL antibody for 6 h. Kupffer cells (KC) or splenocytes and liver lymphocytes were stimulated in vitro by lipopolysaccharide or concanavalinA, respectively. Whole-body iPLA₂β deficiency caused increased apoptosis in liver, spleen, and mesenteric lymph node (MLN). KC from mutant mice showed suppressed release of TNFα and IL-6, while their splenocytes secreted increased levels of IFNγ and IL-17a. Upon CD95/FasL activation, the mutant KC in turn showed exaggerated cytokine release, this was accompanied by an increased release of IFNγ and IL-17a by liver lymphocytes. Aged iPLA₂β(-/-) mice did not show follicular MLN lymphoma commonly seen in aged C57/BL6 mice. Thus, iPLA₂β deficiency renders M1- and Th1/Th17-proinflammation potentially leading to a reduction in age-related MLN lymphoma during aging.
Enhanced Bactericidal Effects of Pyrazinamide Toward Mycobacterium smegmatis and Mycobacterium tuberculosis upon Conjugation to a {Au(I)-triphenylphosphine}+ Moiety (2020)

As part of the quest for new gold drugs, we have explored the efficacy of three gold complexes derived from the tuberculosis drug pyrazinamide (PZA), namely, the gold(I) complex [Au(PPh<sub>3</sub>)(PZA)]OTf (<b>1</b>, OTf = trifluoromethanesulfonate) and two gold(III) complexes [Au(PZA)Cl<sub>2</sub>] (<b>2</b>) and [Au(PZO)Cl<sub>2</sub>] (<b>3</b>, PZO = pyrazinoic acid, the metabolic product of PZA) against two mycobacteria, <i>Mycobacterium tuberculosis</i> and <i>Mycobacterium smegmatis</i>. Only complex <b>1</b> with the {Au(PPh<sub>3</sub>)}<sup>+</sup> moiety exhibits significant bactericidal activity against both strains. In the presence of thiols, <b>1</b> gives rise to free PZA and {Au(PPh<sub>3</sub>)}-thiol polymeric species. A combination of PZA and the {Au(PPh<sub>3</sub>)}-thiol polymeric species appears to lead to enhanced efficacy of <b>1</b> against <i>M. tuberculosis</i>.
CCDC 1590307: Experimental Crystal Structure Determination : 2,8-didodecylthieno[3',2':6,7][1]benzothieno[3,2-b]thieno[3,2-g][1]benzothiophene (2020)

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Expression of Prostaglandin D2 Synthase in Activated Eosinophils in Nasal Polyps (2007)

Prostaglandin D2 was actively produced by an EG2 and HPGDS double-positive subpopulation of activated eosinophils that had infiltrated into nasal polyps.
Analysis of universal adversarial perturbations (2017)

Deep networks have recently been shown to be vulnerable to universal perturbations: there exist very small image-agnostic perturbations that cause most natural images to be misclassified by such classifiers. In this paper, we propose the first quantitative analysis of the robustness of classifiers to universal perturbations, and draw a formal link between the robustness to universal perturbations, and the geometry of the decision boundary. Specifically, we establish theoretical bounds on the robustness of classifiers under two decision boundary models (flat and curved models). We show in particular that the robustness of deep networks to universal perturbations is driven by a key property of their curvature: there exists shared directions along which the decision boundary of deep networks is systematically positively curved. Under such conditions, we prove the existence of small universal perturbations. Our analysis further provides a novel geometric method for computing universal perturbations, in addition to explaining their properties.
Novell embedded microbump approach for die-to-die and wafer-to-wafer interconnects with variable microbump diameters and down to 5 um interconnect pitch scaling (2019)

In this paper a novel solder-based die-to-die or wafer-to-wafer interconnect approach is introduced. This technique allows for microbump interconnects with different diameters on a single die and allows for pitch scaling down to 5μm A metal damascene process is used to create the metal pad layers for soldering. Solder μm bumps are created by semiadditive electroplating. After embedding the solder μbumps in a partially cured polymer, the wafer surface is planarized and the solder surface is exposed. This results in flat die surfaces of the die before bonding. Using a thermo-compression bonding process these flat surfaces can be aligned, the solder reacts with the metal pad to form a solder joint and the polymer can bond and cure to ensure a void less underfill layer for mechanical strength and increased reliability. The selection of suitable metals and polymers as well as the different process steps together with reliability data will be discussed in detail. Electrical yield and quality of bonding is demonstrated using imec 5μm pitch PTCU/W test vehicle for die to wafer bonding.
Quantitative Assessment of the Cycling Stability of Different Electrochromic Materials and Devices (2023)

Despite the long-standing history of electrochromism, there is a lack of universally accepted methods for quantitatively comparing cycling stability between different electrochromic materials or devices. By proposing a straightforward three-step procedure, we report a simple set of parameters that describe the cycling stability performance the most frequently used electrochromic materials, namely, conducting polymers, transition metal oxides, metallo-supramolecular polymers, and viologens. The main highlights of this procedure are an adequate definition of the testing conditions and the analytical description of the evolution of the performance of materials through continuous cycling. The resulting parameters allow us, not only to perform comparative studies among different materials and devices but also to identify tendencies, and therefore establish the corresponding balance, between the testing conditions and the cycling stability and/or optical performance obtained. This method constitutes a powerful decision-making tool for the academic and industry-related electrochromic community.
Syntheses and Characterizations (2010)

This chapter contains sections titled: Zintl Ions Semiconductor Nanoparticles Synthesis of Metal Nanoparticles References
Wideband or Dual-Band Low-Profile Circular Patch Antenna With High-Gain and Sidelobe Suppression (2018)

This communication presents a wideband or dual-band circular disk antenna with high-gain and sidelobe suppression (SLS). The antenna has a single layer and single-fed configuration. The antenna can operate with the radiation field superposition of TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">12</sub> and TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">14</sub> modes at one frequency, which provides high-gain and SLS. A circle of 10 shorting vias with nonidentical diameters are loaded inside the antenna cavity in order to excite the field superposition of TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">11</sub> and TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">13</sub> modes at another frequency. By modifying the radius of the vias, the resonant frequency with the TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">11</sub> and TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">13</sub> superposition can be tuned closer to or further away from the one with the TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">12</sub> and TM <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">14</sub> superposition. In this way, a wideband or dual-band behavior can be obtained with high-gain and SLS. The proposed antenna achieves the impedance bandwidth of 6.46% for the wideband case, which is over 6 times wider than the previous literature. In the dual-band case, the bandwidth is 1.48% and 1.61% at each band. For both cases, the gain and the SLS are higher than 15 dBi and 10 dB within the operating bands, respectively. Measurements are carried out with prototypes and agree well with simulations.
A Novel Silicon High Voltage Vertical MOSFET Technology for a 100W L-Band Radar Application (2008)

The silicon vertical MOSFET RF power amplifier described in this paper is the industry's first to utilize high voltage vertical technology. Operating under pulse conditions of 200 musec pulse width and 10% duty cycle it delivers more than 100 W of peak power. Operating in Class AB with only 50 mA of bias current the device achieves more than 20 dB of gain and 47% power added efficiency at P1dB compression across 200 MHz of bandwidth at L-Band from 1.2 GHz to 1.4 GHz. The DC characteristics include a BVdss of 115 volts enabling high voltage operation with a 48 V power supply.
New Opportunity for Carbon‐Supported Ni‐based Electrocatalysts: Gas‐Phase CO2 Methanation (2021)

Abstract The cost‐effectiveness and excellent performance of conductive‐carbon‐supported Ni‐based electrocatalysts make them attractive materials for hydrogen oxidation and evolution reactions. However, they were previously unused in gas‐phase hydrogenation reactions. In this work, we have expanded the applicability of commercially available advanced Ni/C, NiMo/C and NiRe/C materials from electrocatalysis to heterogeneous catalysis of CO 2 methanation. Our catalytic testing efforts indicate that the monometallic Ni/C material demonstrates the best CO 2 methanation properties, achieving an excellent CO 2 conversion of 83 % at 400 °C with nearly complete selectivity to CH 4 of 99.7 %, plus exhibiting intact performance during 90 h of time‐on‐stream testing. Such catalytic properties are among the highest reported to date among carbon‐supported Ni‐based methanation catalysts. Excellent performance of Ni/C stems from the good dispersion of the Ni nanoparticles over N‐containing carbon support material.
Supplemental Figure 2 from The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer (2023)

&lt;p&gt;Figure S2&lt;/p&gt;
Feature contrast in dose-equalization schemes used for electron-beam proximity control (1996)

Dose equalization by the GHOST technique fails to provide homogeneous contrast when the two-Gaussian model does not adequately portray the beam-energy dose distribution. This leads to an undesirable pattern dependence to the contrast obtained. The degree to which this breakdown occurs is shown in computer simulation. The most severe breakdown occurs in enclosed (annular) structures where the effect of ‘‘higher order’’ Gaussian deposition peaks are concentrated. Unanticipated background fluctuations of about 10% of the nominal exposure dose are obtained. As a result of this study, test structures are proposed which can extend the utility of dose equalization.
ChemInform Abstract: Synthesis of Optically Active Amino Azapenams by the Photolytic Reaction of Chromium Aminocarbene Complexes with N‐Protected Imidazolines. (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Design of DNG-type Substrate-Integrated-Waveguide Resonators to Replace the Conventional Metallic Waveguide for the Military Satellite Transceiver (2013)

A new and significantly small guided and resonant structure is suggested to take over bulky metallic hollow waveguides used in military satellite transceivers. Below Ku-band, the conventional waveguides resulting in quite heavy transceivers will be replaced by the low profile SIW(substrate integrated waveguide) structures that are distinguished from the others in that the suggested ones have much lower cut-off frequencies by the circuital configuration of DNG(dobule negative) constitutive parameters and become even smaller than the other SIWs. The design scheme is validated by the circuit and full-wave simulations from the guided, resonant, and coupled structures. Besides, a bandpass filter as the suggested coupled structure is fabricated with a cheap substrate in a low-budget fabrication process and its frequency response is measured as verification of the purpose of the design.
P2‐256: Towards the treatment of Alzheimer's disease: Discovery and development of novel subtype‐specific M1 allosteric agonists (2009)

Due to the prominent degeneration of the cholinergic basal forebrain associated with Alzheimer's Disease (AD) the M1 muscarinic acetylcholine receptor has long been implicated as a tractable therapeutic target. Despite the M1 receptor having remained a Phase III clinically-validated target for obtaining cognitive efficacy in AD, no prior effort has met FDA approval due to a failure to achieve subtype-selectivity among the muscarinic receptors, giving rise to severe cholinergic side effects such as poor GI tolerance. An iterative analog approach was used in order to generate chemical libraries around initial hits. Calcium mobilization assays were used in parallel to generate functional potency and efficacy data for all compounds, where off target activity was assessed in a Panlabs lead profiling screen by percent radioligand displacement at 10μM. M1 mutagenesis was driven by hypotheses generated from molecular models of M1 receptor/ligand interactions constructed using Rosetta and RosettaLigand software based on recently reported receptor structural templates (PDB IDs 2RH1 and 3EML). Mutant receptor constructs were produced utilizing Stratagene's Quikchange site directed mutagenesis kit. Pharmacokinetic parameters were determined in a rat plasma-brain-level study using LC/MS detection of drug levels. Whole cell patching was used to measure NMDAR current following drug administration. This work reports the discovery of the first truly subtype-selective M1 allosteric agonist, VU0184670, with EC50 and AChmax values of 150nM and 85%, respectively, with exclusive selectivity versus M2-M5 and no significant ancillary pharmacology. Also, VU0184670 was found to robustly potentiate NMDAR current in rat hippocampal slices. Favorable pharmacokinetics were observed following intraperitoneal dosing of an analog VU0357017 in rats at 10 mg/kg, providing a window with which to assess effects on animal models of cognition in vivo. Finally, mutagenesis efforts aimed at extracellular loop three of the M1 receptor have dramatically decreased the functional potency of VU0184670, providing initial validation for our M1 molecular models as well as target residues for further mutagenesis. The discovery of a potent, truly selective M1 allosteric agonist represents a significant breakthrough for AD treatment and will provide a critical basic tool to allow dissection of M1-mediated efficacy in other disease states such as Schizophrenia.
Adaptive DRX configuration to optimize device power saving and latency of mobile applications over LTE advanced network (2013)

Discontinuous reception (DRX) can be configured as a power saving mechanism for user equipment (UE) in connected mode in the long term evolution advanced (LTE-A) network. Since DRX saves UE's battery power usually at the cost of increased latency, a tradeoff between these two conflicting performance metrics are inevitable. DRX parameters can be optimized for either maximizing power saving or minimizing latency based on the applications running at the UE. In this paper, we first develop an analytical model to estimate power saving achieved and latency incurred by DRX operation. We then propose a scheme to tune DRX parameters in order to keep a balance between these conflicting performance metrics by formulating a multi-objective optimization problem. The tradeoff between power saving and latency is achieved based on the operator's relative preferences for these metrics. We also validate our analytical model by system level simulation results from OPNET Modeler. OPNET simulation results are well aligned with the MATLAB results based on analytical model and the results show that proposed scheme efficiently optimizes the DRX configuration for the battery power saving and latency requirements of various diverse data applications based on the preferences determined by operator.