gebhart/patrepeval huggingface dataset:
Intravoxel incoherent motion imaging predicts exercise‐based rehabilitation response in individuals with low back pain (2021)

Exercises to strengthen and stabilize the trunk musculature are a common conservative treatment strategy for low back pain (LBP), despite the possible presence of impairments in muscle activation in this population. Intravoxel incoherent motion (IVIM) MRI permits evaluation of activation-induced blood flow through diffusion-weighted images that are sensitized to microvascular blood flow. In the current study we aimed to evaluate IVIM signal changes after exercise in patients with LBP compared with pain-free healthy controls and determine if these changes were related to reductions in disability with a 12-week rehabilitation program. We hypothesize that the magnitude of changes in IVIM parameters in the lumbar extensor muscles will be smaller in patients with LBP compared with those without LBP, and that these magnitudes will be correlated with responsiveness to a 12-week, resistance-based exercise program. IVIM MR data for molecular diffusion (D), blood flow pseudodiffusion (D*) and perfusion fraction (f) were collected before and immediately after an ~ 3-min session of high-intensity lumbar extension resistance exercise in 16 healthy participants and 17 participants with LBP. Improvements in LBP-related disability after the 12-week, machine-based, high-intensity exercise rehabilitation program were measured in the LBP group. We observed a significant increase in all IVIM parameters (f, D*, D) in response to exercise (p < 0.0001) and an interaction of group-by-time for D (p = 0.016). Thresholds were identified using receiver operating characteristic (ROC) curves for diffusion and pseudodiffusion coefficients, which predicted a reduction in LBP-related disability in response to the 12-week, exercise-based rehabilitation program. Exercise was associated with an increase in (f), capillary blood flow-based pseudodiffusion (D*) and diffusion coefficient (D), regardless of the presence of LBP. Additionally, subgroup analysis identified patients who were not responsive to the acute exercise session, for whom, based on ROC analysis, there was no clinically significant change in disability following the 12-week program.
Dual Stack Hosts Using "Bump-in-the-API" (BIA) (2002)

This document specifies a mechanism of dual stack hosts using a technique called Bump-in-the-API(BIA) which allows for the hosts to communicate with other IPv6 hosts using existing IPv4 applications. The goal of this mechanism is the same as that of the Bump-in-the- stack mechanism, but this mechanism provides the translation method between the IPv4 APIs and IPv6 APIs. Thus, the goal is simply achieved without IP header translation.
Correction: HIV microarray for the mapping and characterization of HIV-specific antibody responses (2015)

Correction for 'HIV microarray for the mapping and characterization of HIV-specific antibody responses' by Daniela Gallerano et al., Lab Chip, 2015, 15, 1574-1589.
Online resource mapping for SDN network hypervisors using machine learning (2016)

The visualization of Software-Defined Networks (SDN) allows multiple tenants to share the same physical infrastructure and to use their own SDN controllers. SDN virtualization is achieved through an SDN network hypervisor that operates between the tenants' controllers and the SDN infrastructure. In order to provide performance guarantees, resource mapping is required for both data plane as well as control plane for each virtual SDN network. In the context of SDN virtualization, the control plane resources include the network hypervisor, which needs to be assigned to guarantee the performance for each tenant. In previous work, the hypervisor resource mapping is based on offline benchmarks that measure the hypervisor resource consumption against the control plane work load, e.g., control plane message rate. These offline benchmarks vary across different hypervisor implementations, e.g., single or multi-threaded, and depend on the capabilities of the deployed hardware platform, e.g., the used CPU. We propose an online approach based on machine learning techniques to determine the mapping of hypervisor resources to the control workload at runtime. This concept is already successfully applied in the context of self-configuring networks. We propose three models to estimate hypervisor resources and compare them for two SDN hypervisor implementations, namely FlowVisor and OpenVirteX. We show through measurements on a real virtualized SDN infrastructure that resource mappings can be learned on runtime with insignificant error margins.
Data from A Pilot Trial Using Lymphocytes Genetically Engineered with an NY-ESO-1–Reactive T-cell Receptor: Long-term Follow-up and Correlates with Response (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Although adoptive cell therapy can be highly effective for the treatment of patients with melanoma, the application of this approach to the treatment of other solid tumors has been limited. The observation that the cancer germline (CG) antigen NY-ESO-1 is expressed in 70% to 80% and in approximately 25% of patients with synovial cell sarcoma and melanoma, respectively, prompted us to perform this first-in-man clinical trial using the adoptive transfer of autologous peripheral blood mononuclear cells that were retrovirally transduced with an NY-ESO-1–reactive T-cell receptor (TCR) to heavily pretreated patients bearing these metastatic cancers.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; HLA-*0201 patients with metastatic synovial cell sarcoma or melanoma refractory to standard treatments and whose cancers expressed NY-ESO-1 received autologous TCR-transduced T cells following a lymphodepleting preparative chemotherapy. Response rates using Response Evaluation Criteria in Solid Tumors (RECIST), as well as immunologic correlates of response, are presented in this report.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; Eleven of 18 patients with NY-ESO-1&lt;sup&gt;+&lt;/sup&gt; synovial cell sarcomas (61%) and 11 of 20 patients with NY-ESO-1&lt;sup&gt;+&lt;/sup&gt; melanomas (55%) who received autologous T cells transduced with an NY-ESO-1–reactive TCR demonstrated objective clinical responses. The estimated overall 3- and 5-year survival rates for patients with synovial cell sarcoma were 38% and 14%, respectively, whereas the corresponding estimated survival rates for patients with melanoma were both 33%.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; The adoptive transfer of autologous T cells transduced with a retrovirus encoding a TCR against an HLA-A*0201 restricted NY-ESO-1 epitope can be an effective therapy for some patients bearing synovial cell sarcomas and melanomas that are refractory to other treatments. &lt;i&gt;Clin Cancer Res; 21(5); 1019–27. ©2014 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Significant improvements of quantum efficiency of quaternary InAlGaN UV‐LEDs on GaN substrates (2005)

InAlGaN-based 350 nm-band ultraviolet (UV) light-emitting diodes (LEDs) were fabricated on freestanding GaN substrates with low dislocation density. Photoluminescence, cathodoluminescence, and atomic force microscopy measurements revealed that, with increasing growth temperature, the InAlGaN crystalline quality was improved and an In fluctuation effect (with minimal In composition) was maintained. Utilizing optimized InAlGaN growth conditions, the output power and the external quantum efficiency at 100 mA current injection significantly improved to 3.9 mW and 1.1% at the wavelength of 353 nm. (© 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
Analysis of the Interactions of Preproteins with the Import Machinery over the Course of Protein Import into Chloroplasts (1997)

We have investigated the interactions of two nuclear-encoded preproteins with the chloroplast protein import machinery at three stages in import using a label-transfer crosslinking approach. During energy-independent binding at the outer envelope membrane, preproteins interact with three known components of the outer membrane translocon complex, Toc34, Toc75, and Toc86. Although Toc75 and Toc86 are known to associate with preproteins during import, a role for Toc34 in preprotein binding previously had not been observed. The interaction of Toc34 with preproteins is regulated by the binding, but not hydrolysis of GTP. These data provide the first evidence for a direct role for Toc34 in import, and provide insights into the function of GTP as a regulator of preprotein recognition. Toc75 and Toc86 are the major targets of cross-linking upon insertion of preproteins across the outer envelope membrane, supporting the proposal that both proteins function in translocation at the outer membrane as well as preprotein recognition. The inner membrane proteins, Tic(21) and Tic22, and a previously unidentified protein of 14 kD are the major targets of crosslinking during the late stages in import. These data provide additional support for the roles of these components during protein translocation across the inner membrane. Our results suggest a defined sequence of molecular interactions that result in the transport of nuclear-encoded preproteins from the cytoplasm into the stroma of chloroplasts.
In Vivo Measurements of the Insertion Depth of Cochlear Implant Arrays Using Flat-Panel Volume Computed Tomography (2010)

FPCT provides 3D high-resolution radiographic data that enable the determination of the insertion depth angle with high accuracy and, potentially, an angle determination of individual electrodes. Therefore, this low-dose technique is especially appropriate for postoperative investigations after cochlea implantation.
The development of Model Predictive Control in automotive industry: A survey (2012)

Model Predictive Control (MPC) is an established control technique in chemical process control, due to its capability of optimally controlling multivariable systems with constraints on plant and actuators. In recent years, the advances in MPC algorithms and design processes, the increased computational power of electronic control units, and the need for improved performance, safety and reduced emissions, have drawn considerable interest in MPC from the automotive industry. In this paper we survey the investigations of MPC in the automotive industry with particular focus on the developments at Ford Motor Company. First, we describe the basic MPC techniques used in the automotive industry, and the early exploratory investigations. Then we present three applications that have been recently prototyped in fully functional production-like vehicles, highlighting the features that make MPC a good candidate strategy for each case. We finally present our perspectives on the next challenges and future applications of MPC in the automotive industry.
Radical polymerization of new functional monomers: Mono‐ and dimethacryloyl isocyanate containing bisphenol‐A and its derivatives (1996)

New functional monomers mono-and dimethacryloyl isocyanate containing bisphenol-A were prepared on reaction of methacryloyl isocyanate (MAI) with bisphenol-A (BPA) and its derivatives at low temperature. The monomers thus obtained were characterized with IR, UV, and 1H- and 13C-NMR spectra. Radical polymerization of mono-and dimethacryloyl isocyanate containing bisphenol-A and its derivatives was studied in terms of the rate of polymerization, solvent effect, copolymerization, thermal properties, and kinetic measurements of photocrosslinking. Polar solvents such as DMSO and NMP were found to slow the polymerization. Copolymerization of BPA-MAI (M1) with MMA (M2) in DMF was studied at 90°C. The monomer reactivity ratio was calculated to be r1 = 0.17 and r2 = 1.34 according to the method of Fineman–Ross. Functional polymers containing the allyl group were successfully modified and photocrosslinked on irradiation in the presence of benzoin isopropyl ether. The photocrosslinking process follows second-order kinetics. © 1996 John Wiley & Sons, Inc.
Studies of metallic multilayer structures, optical properties, and oxidation using in situ spectroscopic ellipsometry (1998)

In situ spectroscopic ellipsometry (SE) has been successfully used to accurately measure sputter deposition rates and optical constants of un-oxidized metal layers and to control the growth of magnetic multilayers. The structures include [Co/Cu]n, [Co/Au]n, [Co/Ni]n, [Co/Pd]n and [Co/Pd/Au]n. Layer thickness precision is better than ±0.05 nm for layer thicknesses in the range of 0.2 nm to 10 nm. Closed-loop feedback control of layer thickness is also demonstrated. Good consistency was obtained by comparing the in situ SE results to x-ray diffraction measurements. Dynamic oxidation studies of [Co/Au]n and [Co/Ni]n multilayer structures are also presented.
Phase Measurements and Zero Crossings (2016)

In this chapter, a phase measurement method and a zero crossing method are discussed. These methods are relatively simple, but they can operate only under limited conditions. If the input contains only one sinusoidal wave, these methods can provide very accurate frequency measurement. Theoretically these methods can detect the existence of simultaneous signals. The phase measurement approach uses analog in-phase (I) and quadrature (Q) channels as the front end. If the I-Q channels are perfectly balanced, the phase measurement method can measure the frequencies of two input signals. The zero crossing method can measure the frequencies of multiple input signals. However, when multiple signals are present, the frequency accuracy measured by both these two methods will suffer compared with one input signal. Some of these methods need more investigation to determine their performances.
MEMS Microfluidics and BioMEMS - key concepts examples future direction. (2007)

Abstract not provided.
Final Report US-Japan IEC Workshop on Small Plasma and Accelerator Neutron Sources (2008)

Abstract The history of IEC development will be briefly described, and some speculation about future directions will be offered. The origin of IEC is due to the brilliance of Phil Farnsworth, inventor of electronic TV in the US. Early experiments were pioneered in the late 1960s by Robert Hirsch who later became head of the DOE fusion program. At that time studies of IEC physics quickly followed at the University of Illinois and at Penn State University. However, despite many successes in this early work, IEC research died as DOE funding stopped in the mid 1980s. In the early 90’s, R. W. Bussard of EMC revived work with a new major project based on a magnetic assisted IEC. While doing supportive studies for that project, G. Miley proposed a grided “STAR mode” IEC as a neutron source for NAA. This concept was later used commercially by Daimler- Benz in Germany to analysis impurities in incoming ores. This represented a first practical application of the IEC. During this period other research groups at LANL, U of Wisconsin and Kyoto University entered IEC research with innovative new concepts and approaches to IEC physics and applications. Much of this work is documented in the present and in past US-Japan Workshops. At present we stand on the threshold of a new area of IEC applications as neutron source, for isotope production, and as a plasma source. These applications provide a way to continue IEC understanding and technology development with the ultimate goal being a fusion power plant. Indeed, a distinguishing feature of the IEC vs. other fusion confinement approaches is the unique opportunity for “spin off” applications along the way to a power producing plant.
Leaky-mode resonance photonics: an applications platform (2011)

Resonant leaky modes can be induced on dielectric, semiconductor, and metallic periodic layers patterned in one or two dimensions. In this paper, we summarize their physical basis and present their applicability in photonic devices and systems. The fundamental amplitude and phase response of this device class is presented by computed examples for TE and TM polarizations for lightly and heavily spatially modulated gratings. A summary of potential applications is provided followed by discussion of representative examples. In particular, we present a resonant polarizer enabled by a single periodic silicon layer operating across 200-nm bandwidth at normal incidence. Guided-mode resonance (GMR) biosensor technology is presented in which the dual-polarization capability of the fundamental resonance effect is applied to determine two unknowns in a biodetection experiment. In principle, using polarization and modal diversity, simultaneously collected data sets can be used to determine several relevant parameters in each channel of the sensor system; these results exemplify this unique capability of GMR sensor technology. Applying the GMR phase, we show an example of a half-wave retarder design operating across a 50-nm bandwidth at &lambda;~1550 nm. Experimental results using a metal/dielectric design show that surface-plasmon resonance and leaky-mode resonance can coexist in the same device; the experimental results fit well with theoretical simulations.
Specification and management of QoS in real-time databases supporting imprecise computations (2006)

Real-time applications such as e-commerce, flight control, chemical and nuclear control, and telecommunication are becoming increasingly sophisticated in their data needs, resulting in greater demands for real-time data services that are provided by real-time databases. Since the workload of real-time databases cannot be precisely predicted, they can become overloaded and thereby cause temporal violations, resulting in damage or even a catastrophe. Imprecise computation techniques address this problem and allow graceful degradation during overloads. In this paper, we present a framework for QoS specification and management consisting of a model for expressing QoS requirements, an architecture based on feedback control scheduling, and a set of algorithms implementing different policies and behaviors. Our approach gives a robust and controlled behavior of real-time databases, even for transient overloads and with inaccurate runtime estimates of the transactions. Further, performance experiments show that the proposed algorithms outperform a set of baseline algorithms that uses feedback control.
Predictions of Transient Flame Lift-off Length With Comparison to Single-Cylinder Optical Engine Experiments (2014)

A state-of-the-art, grid-convergent simulation methodology was applied to three-dimensional calculations of a single-cylinder optical engine. A mesh resolution study on a sector-based version of the engine geometry further verified the RANS-based cell size recommendations previously presented by Senecal et al. (“Grid Convergent Spray Models for Internal Combustion Engine CFD Simulations,” ASME Paper No. ICEF2012-92043). Convergence of cylinder pressure, flame lift-off length, and emissions was achieved for an adaptive mesh refinement cell size of 0.35 mm. Full geometry simulations, using mesh settings derived from the grid convergence study, resulted in excellent agreement with measurements of cylinder pressure, heat release rate, and NOx emissions. On the other hand, the full geometry simulations indicated that the flame lift-off length is not converged at 0.35 mm for jets not aligned with the computational mesh. Further simulations suggested that the flame lift-off lengths for both the nonaligned and aligned jets appear to be converged at 0.175 mm. With this increased mesh resolution, both the trends and magnitudes in flame lift-off length were well predicted with the current simulation methodology. Good agreement between the overall predicted flame behavior and the available chemiluminescence measurements was also achieved. The present study indicates that cell size requirements for accurate prediction of full geometry flame lift-off lengths may be stricter than those for global combustion behavior. This may be important when accurate soot predictions are required.
Synthesis of Analog and Mixed-Signal Integrated Electronic Circuits (2001)

In today's microelectronics, and in particular the markets for so-called application-specific integrated circuits (ASICs) and high-volume custom ICs, demand is being driven by the increasing level of circuit integration. Today, we can build chips with 100 million transistors, yielding ten million useful logic gates. As a result, complete systems that previously occupied one or more printed circuit boards are being integrated on a few chips or even one single chip. Examples of these so-called system-on-chip (SoC) designs include single-chip digital television and single-chip cameras (ISSCC, 1996). New generations of telecommunication systems include analog, digital, and even radio-frequency (RF) sections on one chip. The technology of choice for these systems remains industry-standard complementary metal oxide semiconductors (CMOS), because of their unsurpassed scaling abilities; that is, when geometric feature sizes shrink with each new generation of CMOS technology, the resulting circuits and devices are not only smaller but also faster, and they consume less power. However, technologies that allow both CMOS and higher-speed bipolar transistors (e.g., BiCMOS, and more recently, embedded SiGe) are also used when needed for high-performance analog or RF circuits. Although most functions in these systems are implemented with digital circuitry, the analog circuits needed at the interface between the electronic system and the “real” world are also being integrated on the same chip for reasons of cost and performance.
Fig Supp 3 from HDAC6 Plays a Noncanonical Role in the Regulation of Antitumor Immune Responses, Dissemination, and Invasiveness of Breast Cancer (2023)

&lt;p&gt;Fig Supp 3&lt;/p&gt;
Parallel plate mode suppressed strip-line fed antenna for CP phased array antenna (2015)

A parallel plate mode (PPM) suppressed strip-line fed antenna with a via-wall is proposed for circular polarization phased array antenna system. By introducing a metal cavity using a via-wall around antenna, radiation characteristic perturbation and mutual coupling are improved. To verify the PPM suppression effects, conventional antenna, which does not have via-walls, and the proposed antenna are compared in 4×4 array configuration. The reflection coefficient variation is reduced and the mutual coupling is improved about 17 dB. The measured antenna gain is 7.05 dBi, and axial ratio is 1.2 dB at designed frequency 9.5 GHz.
ChemInform Abstract: Intermolecular Copper(I) Chloride Mediated Coupling of Alkenyltrialkylstannane Functions: A Convenient Synthesis of Conjugated Diene Systems. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Use of Species-Specific Oligonucleotide Probes to Detect Mycoplasma Gallisepticum, M. Synoviae, and M. Iowae PCR Amplification Products (1996)

Three digoxigenin-labeled oligonucleotide probes, complementary to the variable region of the 16S ribosomal RNA (rRNA) gene of Mycoplasma gallisepticum, M. synoviae, and M. iowae were designed. The oligonucleotides were used in a dot blot hybridization assay. The target DNA is a 780-bp fragment of the 16S rRNA gene of avian mycoplasmas amplified by a single set of primers (multispecies polymerase chain reaction [PCR]). The oligonucleotide probes were specific for their corresponding PCR products at hybridization conditions of 56 C and 50% formamide. The detection limit of the dot blot hybridization assay was approximately 70, 50, and 30 colony-forming units for M. gallisepticum, M. synoviae, and M. iowae, respectively, per 4 microliters of PCR. In general, the oligonucleotide probe dot blotting assay was a more sensitive and effective method of detecting PCR products than detection by gel electrophoresis.