gebhart/patrepeval huggingface dataset:
Seitenspezifische Funktionalisierung von Janusfasern aus rekombinanter Spinnenseide (2022)

Abstract Mittels moderner Biotechnologie können heutzutage neue Materialien mit maßgeschneiderten Eigenschaften entwickelt werden. Ziel dieser Studie war es, funktionalisierbare Janusfasern aus rekombinanten Spinnenseidenproteinen herzustellen. Dabei wurde zunächst das Cystein‐modifizierte Seidenkonstrukt ntag Cys eADF4(κ16) nassgesponnen. Auf den Fasern wurden anschließend mittels Thiol‐En‐Klickchemie Goldnanopartikel (AuNPs) gekuppelt. Als Indikator für eine hohe AuNP‐Beladungsdichte wurde ein deutlich reduzierter spezifischer elektrischer Widerstand der Fasern gemessen. Anschließend wurden mittels Elektrospinnen zweiseitige Janusfasern mit “nicht‐funktionalem” eADF4(C16) auf der einen und “funktionalem” ntag Cys eADF4(κ16) auf der anderen Seite hergestellt. Eine Nachbehandlung wurde etabliert, um die Seidenfasern in Wasser unlöslich zu machen. Es wurde gezeigt, dass die AuNP‐Kupplung ausschließlich auf der ntag Cys eADF4(κ16)‐Seite auftrat. Die hochselektive Funktionalisierung zeigt das Potenzial solcher seidenbasierten Systeme zur Realisierung komplexer bifunktioneller Strukturen mit räumlicher Auflösung im Nanobereich.
Engineering degree programs with technical focus and embedded quality assurance measures: a case study (2009)

This paper discusses various aspects of the design and implementation of the curriculum for three relatively closely related undergraduate engineering programs; namely communication, electronic, and computer engineering. A major distinctive feature of the programs is the emphasis on engineering projects carried out in groups and individually as well. The programs have strong technical focus and are embedded with integrated quality assurance measures, compared with conventional program structures that are offered by other institutions. The educational system is augmented with a multitude of mechanisms that enhance the teaching and learning process. The programs are accredited by both national and international bodies. The programs have proven to be very successful as graduates are well sought after by both industry and government.
Design and Implementation of Phase-Shifted Distributed Feedback Lasers on the Hybrid Silicon platform (2011)

We fabricate, and characterize 36 designs of phase-shifted distributed-feedback lasers, varying κL products and shift lengths, in good agreement with theoretical calculations on the hybrid silicon platform.
SQSTM1 Mutations and Glaucoma (2016)

Glaucoma is the most common cause of irreversible blindness worldwide. One subset of glaucoma, normal tension glaucoma (NTG) occurs in the absence of high intraocular pressure. Mutations in two genes, optineurin (OPTN) and TANK binding kinase 1 (TBK1), cause familial NTG and have known roles in the catabolic cellular process autophagy. TKB1 encodes a kinase that phosphorylates OPTN, an autophagy receptor, which ultimately activates autophagy. The sequestosome (SQSTM1) gene also encodes an autophagy receptor and also is a target of TBK1 phosphorylation. Consequently, we hypothesized that mutations in SQSTM1 may also cause NTG. We tested this hypothesis by searching for glaucoma-causing mutations in a cohort of NTG patients (n = 308) and matched controls (n = 157) using Sanger sequencing. An additional 1098 population control samples were also analyzed using whole exome sequencing. A total of 17 non-synonymous mutations were detected which were not significantly skewed between cases and controls when analyzed separately, or as a group (p > 0.05). These data suggest that SQSTM1 mutations are not a common cause of NTG.
Different Effects of PLGA and Chitosan Scaffolds on Human Cartilage Tissue Engineering (2007)

Clinical application of the cartilage formed by tissue engineering is not practical due to the failure to maintain long-term tissue structural integrity. One of the important factors for maintaining integrity is the biomaterial for a scaffold. The purpose of the current study was to evaluate the difference between poly-lactic glycolic acid (PLGA) and chitosan as scaffolds. Human auricular chondrocytes were used. Chondrocyte-scaffold complexes were implanted in nude mice and analyzed at 4, 8, 12, 16, and 24 weeks after implantation. The volume of chondrocyte-PLGA complexes decreased rapidly. The volume of chondrocyte-chitosan complexes was well maintained with a slow decrease rate. In histological findings, mature cartilage was formed by 4 weeks in the PLGA group. However, cartilage structure was hardly found after 16 weeks. In the chitosan group, mature cartilage was detected at 8 weeks and cartilage formation became more marked with time. The expression of type II collagen protein and mRNA became weaker with time in the PLGA group. However, the expression in the chitosan group was strong for the whole period. These results suggest that chitosan is a superior scaffold for cartilage tissue engineering in terms of the maintenance of structural integrity. It is expected that after some modification for more rapid chondrogenesis, chitosan scaffolds may become one of the most useful scaffolds for cartilage tissue engineering.
BRET-Based Method For Detection of Specific RNA Species (2007)

RNA detection and quantitation is a common necessity in modern molecular biology research. Most methods, however, are complex and/or time-intensive. Presented here is a BRET (bioluminescene resonance energy transfer)-based method that can accomplish the task of RNA identification quickly and easily. By conjugating BRET enzymes to two different oligonucleotides that are complementary to the same target sequence, probes were developed that could detect RNA using a solution-based assay. This assay was optimized for spacer length between the binding sites (found to be 10 nucleotides), and sensitivity was determined to be 1 microg for a specific species of RNA within a mixed population. Specificity of the assay was assessed using in vitro transcribed cRNA and found to be statistically siginificant ( p = 3.11 x 10 (-6), ANOVA, multiple range test). This assay represents a possibility for a less technically demanding, streamlined alternative to canonical RNA assays.
Copeptin in the Differential Diagnosis of Hyponatremia (2008)

Copeptin measurement reliably identifies patients with primary polydipsia but has limited utility in the differential diagnosis of other hyponatremic disorders. In contrast, the copeptin to U-Na ratio is superior to the reference standard in discriminating volume-depleted from normovolemic hyponatremic disorders.
Metal-Catalyzed Cyclopropene Rearrangements for Benzannulation: Evaluation of an Anthraquinone Synthesis Pathway and Reevaluation of the Parallel Approach via Carbene-Chromium Complexes (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMetal-Catalyzed Cyclopropene Rearrangements for Benzannulation: Evaluation of an Anthraquinone Synthesis Pathway and Reevaluation of the Parallel Approach via Carbene-Chromium ComplexesM. F. Semmelhack, Suzzy Ho, D. Cohen, M. Steigerwald, M. C. Lee, G. Lee, Adam M. Gilbert, William D. Wulff, and Richard G. BallCite this: J. Am. Chem. Soc. 1994, 116, 16, 7108–7122Publication Date (Print):August 1, 1994Publication History Published online1 May 2002Published inissue 1 August 1994https://pubs.acs.org/doi/10.1021/ja00095a014https://doi.org/10.1021/ja00095a014research-articleACS PublicationsRequest reuse permissionsArticle Views770Altmetric-Citations54LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Through-Plane Water Transport Visualization in a PEMFC by Visible and Infrared Imaging (2011)

In this study, water transport and thermal profile in the through-plane direction of a proton exchange membrane fuel cell (PEMFC) gas diffusion layer (GDL) are reported. Direct optical and infrared access to both cathode and anode GDLs are provided in a typical 50 cm2 test section. Dynamic visualization (pixel resolution of ∼0.6 μm at 28 Hz) of liquid water transport and emergence in the gas distribution channels and diffusion layers are reported and the underlying transport processes are discussed. The temperature distributions across the anode and cathode GDL are also measured with a high resolution infrared camera with a pixel resolution of 5 μm at 30 Hz.
Introduction to the Issue on Quantum and Nanoscale Photonics (2012)

The purpose of this issue is to highlight the recent progress and trends in the development of novel nano- and quantum photonic technologies. The articles published in this issue cover a broad range of areas, including: 1) novel nanophotonic light sources-both classical (lasers) and nonclassical (single- and entangled photon sources); 2) nonlinear optics in nanophotonic structures; 3) quantum optics and quantum information processing based on nanophotonics platform; 4) efficient devices for optical interconnects and optical information processing based on novel nanophotonic structures. This issue contains 25 papers, including eight invited, authored by well-established research groups and promising scientists from all over the world. The invited articles include extended reviews on entangled photon generation using silicon nanowire waveguides; cavity quantum electrodynamics and lasing oscillation in single quantum dot photonic crystal nanocavity systems; quantum plasmonic circuits; theoretical analysis of few-photon single-atom cavity quantum electrodynamics; semiconductor quantum dot micropillar microcavities for quantum optics in solid state; nanofiber-based optical trapping of cold neutral atoms; switching and counting with atomic vapors in photonic-crystal fibers; and production of multiple diamondbased single-photon sources. The contributed articles cover a broad variety of key nanophotonics and quantum photonics research areas, including recently obtained results on bright single-photon emission from a quantum dot in a circular Bragg grating microcavity, supercontinuum generation in nanostructured silicon waveguides, electrically driven photonic crystal nanocavity devices, and silicon quantum dots.
Found ations of assumption-based truth maintenance systems: preliminary report (1987)

In this paper we (1) define the concept of a Clause Management System (CMS) -- a generalization of de Kleer's ATMS, (2) motivate such systems in terms of efficiency of search and abductive reasoning, and (3) characterize the computation affected by a CMS in terms of the concept of prime implicants.
Graphic stereo raster injected verification subsystem for photogrammetric acquisition (1986)

Summary form only given. The Laboratories of Photogrammetry and Microinformatics of the Swiss Federal Institute of Technology of Lausanne have developed, in collaboration with the industry, a graphical verification system. The main innovations of this system, in comparison with the above cited existant systems, are full editing facilities, the possibility to include the height information, and a rather low price. Furthermore, the system can be used as a peripheral for analytical or analog stereo plotters. These innovations are due to the development of a powerful display architecture with build-in dedicated panning functionality. This paper describes the characteristics of the hardware and the possibilities provided by the software. The system is based on a Motorola microprocessor and NEC graphical controller chips. It allows the operator to move in real-time (panning) in a virtual working space of 32000&amp;times;32000 pixels, with a vertical and horizontal resolution of 1 pixel
G‐Quadruplex‐Filtered Selective Ion‐to‐Ion Current Amplification for Non‐Invasive Ion Monitoring in Real Time (2023)

Living cells efflux intracellular ions for maintaining cellular life, so intravital measurements of specific ion signals are of significant importance for studying cellular functions and pharmacokinetics. In this work, de novo synthesis of artificial K<sup>+</sup> -selective membrane and its integration with polyelectrolyte hydrogel-based open-junction ionic diode (OJID) is demonstrated, achieving a real-time K<sup>+</sup> -selective ion-to-ion current amplification in complex bioenvironments. By mimicking biological K<sup>+</sup> channels and nerve impulse transmitters, in-line K<sup>+</sup> -binding G-quartets are introduced across freestanding lipid bilayers by G-specific hexylation of monolithic G-quadruplex, and the pre-filtered K<sup>+</sup> flow is directly converted to amplified ionic currents by the OJID with a fast response time at 100 ms intervals. By the synergistic combination of charge repulsion, sieving, and ion recognition, the synthetic membrane allows K<sup>+</sup> transport exclusively without water leakage; it is 250× and 17× more permeable toward K<sup>+</sup> than monovalent anion, Cl<sup>-</sup> , and polyatomic cation, N-methyl-d-glucamine<sup>+</sup> , respectively. The molecular recognition-mediated ion channeling provides a 500% larger signal for K<sup>+</sup> as compared to Li<sup>+</sup> (0.6× smaller than K<sup>+</sup> ) despite the same valence. Using the miniaturized device, non-invasive, direct, and real-time K<sup>+</sup> efflux monitoring from living cell spheroids is achieved with minimal crosstalk, specifically in identifying osmotic shock-induced necrosis and drug-antidote dynamics.
A time-domain equalizer minimizing intersymbol and intercarrier interference in DMT systems (2002)

Discrete multitone modulation allows for a simple receiver structure if the impulse response of the communication channel is shorter than the cyclic prefix. In ADSL, a time-domain equalizer (TEQ) is used to fulfil this requirement. Without a TEQ, unwanted intercarrier interference (ICI) and intersymbol interference (ISI) occur. In this paper, quadratic forms are developed to calculate the contributions of ICI and ISI to the desired signal. Based on these expressions, a new method for calculating the TEQ coefficients, which minimizes the effects of ICI, ISI, and additive noise, is derived. Simulations in the context of ADSL compare the performance of this new algorithm with one that is state of the art.
Hypersonic Attenuation in Sb Doped Germanium (1971)

Hypersonic attenuation in Sb doped Ge is measured. In the attenuation vs. temperature curve, a large peak is found at 1.8°K. A hypersonic sournd used is longitudinal waves of 1 GHz propagating along the &lt;111&gt; axis of Ge crystal which contained about 1×10 14 , 1×10 15 and 1×10 16 /cm 3 donors. The above attenuation peak seems to be due to the electronic relaxation between the singlet and the triplet states of the donors in Ge, as discussed by M. Pomerantz in the case of As- or P-doped Ge.
Reformulating Parenteral Multivitamin Preparations (1980)

Journal Article Reformulating Parenteral Multivitamin Preparations Get access Ram Murty, Ph.D., Ram Murty, Ph.D. Lypho-Med, Inc. Chicago, IL 60651 Search for other works by this author on: Oxford Academic Google Scholar John Kapoor, Ph.D. John Kapoor, Ph.D. Lypho-Med, Inc. Chicago, IL 60651 Search for other works by this author on: Oxford Academic Google Scholar American Journal of Hospital Pharmacy, Volume 37, Issue 6, 1 June 1980, Pages 789–790, https://doi.org/10.1093/ajhp/37.6.789 Published: 01 June 1980
Identification and Synthesis of Products Isolated during Metabolism Studies of Tilmicosin (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIdentification and Synthesis of Products Isolated during Metabolism Studies of TilmicosinHerbert A. Kirst, Alvin L. Donoho, Lawrence C. Creemer, Julie A. Wind, Donnis M. Berry, John L. Occolowitz, and Jonathan W. PaschalCite this: J. Agric. Food Chem. 1994, 42, 5, 1219–1222Publication Date (Print):May 1, 1994Publication History Published online1 May 2002Published inissue 1 May 1994https://pubs.acs.org/doi/10.1021/jf00041a032https://doi.org/10.1021/jf00041a032research-articleACS PublicationsRequest reuse permissionsArticle Views127Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Formation of a solid electrolyte interface on single wall carbon nanotube electrodes in lithium ion batteries (2009)

The formation of a solid electrolyte interface (SEI) at the surface of a SWNT electrode was investigated by SEM, TEM, XRD, and Raman spectroscopy. These analyses were carried out at different charge-discharge cycles, showing the cycle dependent character of the SEI formation. The changes in chemical species of SEI with increased number of cycles have been examined. This study shows by XRD, that inorganic species of SEI are LiF and Li2CO3, and that the SEI formation depends on the number of discharge-charge cycles.
Providing multimedia services to a diverse set of consumer devices (2002)

This paper describes an assortment of techniques and a system to adapt multimedia content. The ability to do so allows service providers to offer a wide range of multimedia services to users with various client capabilities. We present a system that is capable of serving a variety of client devices. To do so, we propose novel transcoding and video summarization algorithms. Additionally, we describe a system that invokes these algorithms dynamically as a function of the network, terminal and user information. The impact on the consumer is the added functionality that can be realized and the quality of their service.
Organic photosensitive cells grown on rough electrode with nano-scale morphology control (2023)

An optoelectronic device and a method for fabricating the optoelectronic device includes a first electrode disposed on a substrate, an exposed surface of the first electrode having a root mean square roughness of at least 30 nm and a height variation of at least 200 nm, the first electrode being transparent. A conformal layer of a first organic semiconductor material is deposited onto the first electrode by organic vapor phase deposition, the first organic semiconductor material being a small molecule material. A layer of a second organic semiconductor material is deposited over the conformal layer. At least some of the layer of the second organic semiconductor material directly contacts the conformal layer. A second electrode is deposited over the layer of the second organic semiconductor material. The first organic semiconductor material is of a donor-type or an acceptor-type relative to the second organic semiconductor material, which is of the other material type.
A CMOS image sensor with draining only modulation pixels for fluorescence lifetime imaging (2011)

Fluorescence lifetime imaging is becoming a powerful tool in biology. A charge-domain CMOS Fluorescence Lifetime
Imaging Microscopy (FLIM) chip using a pinned photo diode (PPD) and the pinned storage diode (PSD) with different
depth of potential wells has been previously developed by the authors. However, a transfer gate between PPD and PSD
causes charge transfer noise due to traps at the channel surface. This paper presents a time-resolved CMOS image sensor
with draining only modulation pixels for fluorescence lifetime imaging, which removes the transfer gate between PPD and
PSD. The time windowing is done by draining with a draining gate only, which is attached along the carrier path from
PPD to PSD. This allows us to realize a trapping less charge transfer between PPD and PSD, leading to a very low-noise
time-resolved signal detection. A video-rate CMOS FLIM chip has been fabricated using 0.18μm standard CMOS pinned
diode image sensor process. The pixel consists of a PPD, a PSD, a charge draining gate (TD), a readout transfer gate (TX)
between the PSD and the floating diffusion (FD), a reset transistor and a source follower amplifier transistor. The pixel
array has 200(Row) x 256(Column) pixels and the pixel pitch is 7.5μm. Fundamental characteristics of the implemented
CMOS FLIM chip are measured. The signal intensity of the PSD as a function of the TD gate voltage is also measured.
The ratio of the signal for the TD off to the signal for the TD on is 212 : 1.
Novel Layer-by-layer Complexation Technique and Properties of the Fabricated Films (1999)

A novel layer-by-layer complex-fabrication technique for multilayer film assembly was developed by alternatively dipping desired substrates in macromolecular ligands and Eu3+ ion solutions. A water-soluble, luminescent thiophene-based polymer, viz., poly[2,5-(3-carboxymethyl urethanyl ethyl) thiophene] (H-PURET), was prepared and used as the macromolecular ligand. Multilayer deposition was monitored using UV-visible spectroscopy by following the absorbance increase due to the deposition of the polymer layer. Multilayer thin films were characterized using infrared and fluorescence spectroscopic techniques, transmission electron microscopy (TEM), and energy-dispersive X-ray spectrometry (EDXS). The conductivity and the electroluminescence properties of the conjugated polymer−Eu3+ complex multilayer films were also measured. The observed electroluminescence intensity of conjugated polymer−metal complex multilayer film was about 2 times higher than for the conjugated polymer by itself. The approach is general in that other macroligands and metal ions may be employed.
Nonideality in Silicone Network Formation via Solvent Swelling and 1H Double-Quantum NMR (2018)

The versatile cross-linking chemistry of poly(dimethylsiloxane) (PDMS)-based materials affords a large research space in which polymers with widely varying elastomeric properties may be synthesized. Parameters such as chain length, cross-link density, cross-link functionality, filler content, and chain chemistry can all be modified to produce materials with specific physical and mechanical properties. Commercial polysiloxane-based, “silicone” elastomers are generally intractable, which makes the precise characterization of their networks problematic. We report here the application of equilibrium solvent uptake analysis and 1H double-quantum nuclear magnetic resonance (1H DQ NMR) spectroscopy to determine the network topology of end-linked PDMS networks with nonideal network topology. Despite their structural complexity, we can quantify both the classical and nonclassical contributions to network structure using 1H DQ NMR which are in reasonable agreement with solvent uptake data. These findings serve as the foundation for future investigations of even more complex commercial silicones using 1H DQ NMR.