gebhart/patrepeval huggingface dataset:
Tunability and monitoring of chromatic dispersion and PMD in optical networks (2003)

High-bit-rate (/spl ges/10 Gb/s/channel) transmission systems are highly susceptible to deleterious optical-fiber-based effects, such as chromatic dispersion, polarization-mode dispersion (PMD), and nonlinearities. Systems are designed such that these degrading effects are either minimized or compensated. This paper deals with the need in /spl ges/40 Gb/s/channel optical networks for: (i) tunable dispersion compensation, and (ii) dynamic monitoring of the signal degrading effects.
Modeling contextual factors of click rates (2007)

In this paper, we develop and evaluate several probabilistic models of user click-through behavior that are appropriate for modeling the click-through rate of items that are presented to the user in a list. Potential applications include modeling the click-through rates of search results from a search engine, items ranked by a recommendation system, and search advertisements returned by a search engine. Our models capture contextual factors related to the presentation as well as the underlying relevance or quality of the item. We focus on two types of contextual factors for a given item; the positional context of the item and the quality of the other results. We evaluate our models on a search advertising dataset from Microsoft’s Live search engine and demonstrate that modeling contextual factors improves the accuracy of click-through models.
Electronic and molecular structure of variable-spin metal complexes. Spin state dependent crystal and molecular structures of [FeIII(5-OCH3Salmeen)2]PF6 (S = 5/2), [FEIII(3-OCH3Salmeen)2]PF6 (S = 1/2), and [FeIII(5-NO2Salmeen)2]PF6 (S = 1/2) (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTElectronic and molecular structure of variable-spin metal complexes. Spin state dependent crystal and molecular structures of [FeIII(5-OCH3Salmeen)2]PF6 (S = 5/2), [FEIII(3-OCH3Salmeen)2]PF6 (S = 1/2), and [FeIII(5-NO2Salmeen)2]PF6 (S = 1/2)P. Greig Sim, Ekk Sinn, Randall H. Petty, Connie L. Merrill, and Lon J. WilsonCite this: Inorg. Chem. 1981, 20, 4, 1213–1222Publication Date (Print):April 1, 1981Publication History Published online1 May 2002Published inissue 1 April 1981https://pubs.acs.org/doi/10.1021/ic50218a051https://doi.org/10.1021/ic50218a051research-articleACS PublicationsRequest reuse permissionsArticle Views114Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Prediction of the Persistence of Relationships in Social Networks, Considering Previous Reciprocity and Duration (2018)

The aim of the paper is to identify permanent or developing relationships between users of the social network and the prediction of survival or ending of such a relationship. We consider a social network with already identified links between users and characteristics of these links. The social network is being analyzed in the longer period of time, with particular attention to the dynamics of development of it as well as relations between users. The dataset collected for the sake of described work is based on the Polish socio-political blog portal salon24.pl. We aggregate attributes of given relations such as: number of interactions, reciprocity, continuity and time of day when the interactions take place. The purpose of this analysis is to build a model that allows estimating the situation that prevails in the network from the point of view of a specific user. The research results allow to determine how important are links with other users, which ones are so strong that they can be considered as permanent, and in which ones it is worth investing in order to improve their position in the social network.
Physics-Driven Mask R-CNN for Physical Needle Localization in MRI-Guided Percutaneous Interventions (2021)

Discrepancies between the needle feature position on magnetic resonance imaging (MRI) and the underlying physical needle position could increase localization errors during needle-based targeting procedures in MRI-guided percutaneous interventions. This work aimed to develop a deep learning-based framework to automatically localize the physical needle position using only the needle features on MR images. Physics-based simulations were performed to generate single-slice and 3-slice images with needle features from a range of underlying needle positions and MRI parameters to form datasets for training single-slice and 3-slice Mask Region-Based Convolutional Neural Network (R-CNN) models for physical needle localization. Ex vivo tissue images were combined with simulated needle features for fine-tuning. Next, the physics-driven Mask R-CNN models were combined with a previously developed Mask R-CNN model for needle feature localization to form an automated framework to localize the physical needle. To test the accuracy of the proposed framework, both single-slice and 3-slice MRI data were acquired from needle insertion experiments in ex vivo tissue phantoms. Using the single-slice model, the proposed framework achieved sub-millimeter physical needle localization accuracy on single-slice images aligned with the needle. The fine-tuning step improved needle localization accuracy in ex vivo tissue data. The 3-slice model further reduced the through-plane physical needle localization error in situations where the imaging plane may be misaligned with the needle. The processing time of the framework using both models was 200 ms per frame. The proposed framework can achieve physical needle localization in real time to support MRI-guided interventions.
Apparent richness and community composition of Bacteria and Archaea in geothermal springs (2009)

The archaeal and bacterial 16S rRNA gene diversities of the Polihnitos (89 degrees C), Edipsos (81.8 degrees C), Thermopiles (38.9 degrees C), Eleftheres (41.2 degrees C) and Lagadas (35.2 degrees C) geothermal springs in Greece were investigated. The abundance of prokaryotic cells varied between 0.02 x 10(-5) and 0.92 x 10(-5) cells ml(-1). A total of 227 archaeal and 501 bacterial clones were analysed, which were attributed to 85 and 121 operational taxonomic units (OTUs), respectively. Library clone coverage, based on Good's C estimator, was satisfactory (&gt;75%), except for the Archaea in Thermopiles (similar to 40%) and Eleftheres (similar to 60%) Most of the archaeal phylotypes were related to sequences of yet-uncultivated microorganisms retrieved from terrestrial geothermal springs, deep-sea hydrothermal vents and the Subsurface. A much higher number of bacterial phylotypes was related to cultivated microorganisms from similar environments. The thermophilic nature of most of the discovered phylotypes was also Supported by their high G+C content, which was positively correlated with the springs' tempera tu res. The springs Showed different diversity patterns for Bacteria and Archaea, with Bacteria having higher diversity only in Polihnitos and Lagadas springs. The Shannon diversity index H' showed larger variation for Archaea (0.23 to 3.44) than for Bacteria (1.22 to 3.03) and was unrelated to the prevailing temperature, pH, salinity and dissolved oxygen content. Archaeal and bacterial clone libraries respectively contained 50 to 94.1 and 68.8 to 96.2% rare phylotypes (i.e. those that appear only once or twice in the clone library), indicating the importance of rare phylotypes in shaping community diversity.
Supplementary material and methods from Fibroblast Activation Protein α-Targeted CD40 Agonism Abrogates Systemic Toxicity and Enables Administration of High Doses to Induce Effective Antitumor Immunity (2023)

&lt;p&gt;Additional details on methods used for SPR assays, NanoString RNAseq and cynomolgus monkey studies&lt;/p&gt;
Efficient Photocatalytic PFOA Degradation over Boron Nitride (2020)

Concern over water contamination by per/polyfluoroalkyl substances (PFAS) has highlighted the lack of effective treatment approaches. Photocatalysis offers advantages of using ambient conditions for reaction, air as the oxidant, and light as the energy source, but identifying photoactive materials is challenging. Herein, we report that boron nitride (BN) degrades PFOA upon irradiation with 254 nm light. The ability of BN to degrade PFOA photocatalytically has previously been unreported and is unexpected, because its band gap is too large for light absorption. On the basis of scavenger results, we suggest that PFOA degrades in the presence of BN via a hole-initiated reaction pathway similar to the TiO2 case and involves superoxide/hydroperoxyl and hydroxyl radicals. We surmised that defects allow BN to absorb in the UVC range and to photogenerate reactive oxygen species. Sealed batch studies indicated BN was ∼2 and ∼4 times more active than TiO2, before and after ball milling the material, respectively. BN can be reused, showing no decrease in activity over three cycles. BN was active for the photocatalytic degradation of GenX, another PFAS of concern. These findings present fresh opportunities for materials design and for the re-evaluation of other wide band gap semiconductors for PFAS photocatalytic degradation.
HSP70‐related proteins in bovine skeletal muscle (1989)

Constitutive expression of HSP70-related proteins was detected in a variety of bovine tissues using a specific antibody. All tissues contained a 73 kilodalton protein. A lower molecular weight form (72 kilodaltons) that co-migrated on two-dimensional gels with the stressed-induced HSP70 was present in high levels in bovine skeletal muscle, but absent from rat skeletal muscle. Two-dimensional gel analysis revealed several isoforms for both the 73 and 72 kilodalton forms. Purification of HSP70-related proteins from bovine skeletal muscle, thymus gland and rat skeletal muscle demonstrated that the antibody recognized all the forms present in the tissue homogenates. The two proteins are similar but distinct as detected by one-dimensional peptide mapping. The lower molecular form was not present in fetal tissue but was detectable in newborn animals, suggesting that the levels are regulated during development.
NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis (2020)

NOTCH receptor signaling plays a pivotal role in liver homeostasis and hepatocarcinogenesis. However, the role of NOTCH pathway mutations and the NOTCH target gene HES5 in liver tumorigenesis are poorly understood. Here we performed whole-exome sequencing of 54 human HCC specimens and compared the prevalence of NOTCH pathway component mutations with the TCGA-LIHC cohort (N = 364). In addition, we functionally characterized the NOTCH target HES5 and the patient-derived HES5-R31G mutation in vitro and in an orthotopic mouse model applying different oncogenic backgrounds, to dissect the role of HES5 in different tumor subgroups in vivo. We identified nonsynonymous mutations in 14 immediate NOTCH pathway genes affecting 24.1% and 16.8% of HCC patients in the two independent cohorts, respectively. Among these, the HES5-R31G mutation was predicted in silico to have high biological relevance. Functional analyses in cell culture showed that HES5 reduced cell migration and clonogenicity. Further analyses revealed that the patient-derived HES5-R31G mutant protein was non-functional due to loss of DNA binding and greatly reduced nuclear localization. Furthermore, HES5 exhibited a negative feedback loop by directly inhibiting the NOTCH target HES1 and downregulated the pro-proliferative MYC targets ODC1 and LDHA. Interestingly, HES5 inhibited MYC-dependent hepatocarcinogenesis, whereas it promoted AKT-dependent liver tumor formation and stem cell features in a murine model. Thus, NOTCH pathway component mutations are commonly observed in HCC. Furthermore, the NOTCH target gene HES5 has both pro- and anti-tumorigenic functions in liver cancer proposing a driver gene dependency and it promotes tumorigenesis with its interaction partner AKT.
Humoral and Cellular Response of Transplant Recipients to a Third Dose of mRNA SARS-CoV-2 Vaccine: A Systematic Review and Meta-analysis (2022)

A third dose SARS-CoV-2 mRNA vaccine should be strongly considered in transplant recipients. Limitations included lack of controlled studies and clinically relevant thresholds to determine response to vaccination.
Effect of long-term rigid gas-permeable contact lens wear on keratoconus progression (2020)

Based on corneal tomographic evaluation over 5-6 years, the effects of long-term RGP-CL wear had no effect on KC progression.
Supplementary Figure 2 from CD4<sup>+</sup> T-Cell Help in the Tumor Milieu Is Required for Recruitment and Cytolytic Function of CD8<sup>+</sup> T Lymphocytes (2023)

Supplementary Figure 2 from CD4&lt;sup&gt;+&lt;/sup&gt; T-Cell Help in the Tumor Milieu Is Required for Recruitment and Cytolytic Function of CD8&lt;sup&gt;+&lt;/sup&gt; T Lymphocytes
Effect of Synthetic Retinoid, TAC-101, on Experimental Autoimmune Disease (2002)

The effect of 4-[3,5-bis(trimethylsilyl)benzamido] benzoic acid (TAC-101), one of the synthetic retinoids, on collagen-induced arthritis (CIA) in mice and experimental autoimmune encephalomyelitis (EAE) in rats was studied. TAC-101 at doses of 5 and 20 mg/kg clearly inhibited the development of CIA in terms of the swelling of fore- and hind-limbs and bone destruction in knee joints. TAC-101 also suppressed the production of anti-type II collagen (CII) IgG antibody and delayed-type hypersensitivity (DTH) against CII. In addition, TAC-101 delayed the onset and development of EAE but did not affect the maximum symptom of EAE in rats. The elevation of serum antimyelin basic protein (MBP) antibody and DTH to MBP on day 13 clearly suppressed by TAC-101 in EAE rats. Moreover, TAC-101 inhibited the IL-1beta-induced PGE(2) production by MG-63 cells, human osteoblast-like cells, through the suppression of cyclooxygenase II mRNA expression. These findings suggest that TAC-101 inhibits CIA in mice and EAE in rats due to the suppression of immune response to auto-antigen and the production of PGE(2).
Manic episodes are associated with grey matter volume reduction — a voxel‐based morphometry brain analysis (2010)

We found strong evidence for a linear correlation between a decrease in DLPFC volume and the lifetime number of manic episodes in patients with bipolar I disorder. Interestingly, DLPFC is known to be important for executive functions and the findings in this study might hence be linked to the executive cognitive deficits associated with bipolar disorder.
Palladium dispersion effects on wet methane oxidation kinetics (2020)

The catalytic activity for dry and wet methane oxidation over a series of palladium–alumina catalysts with systematically varied palladium loadings and PdO dispersions was measured and compared with conceptual multiscale simulations.
ChemInform Abstract: PHOTOCHEMICAL CYCLIZATION OF 4‐METHALLYL‐4‐METHYLCYCLOPENTENONE. 220 MHZ NUCLEAR MAGNETIC RESONANCE SPECTRA OF TRICYCLO(3.3.0.02,7)OCTANES (1976)

Abstract Aus dem Hydroxyketon (Ia) entsteht über das Tosylat (Ib) das Bromid (Ic), das weiter zu (II) bromiert und dann zum Dien (III) dehydrobromiert werden kann.
Cost-Efficient and Reliable Reporting of Highly Bursty Video Game Crash Data (2017)

Video game crash events are characterized primarily by large media payloads and by highly bursty traffic patterns, with hundreds of thousands or millions of reports being issued in only a few minutes. These events are invaluable in quickly responding to game breaking issues that directly impact user experience. Even the slightest delay in capturing, processing and reporting these events can lead to user abandonment and significant financial cost.
Optimal reverse carpooling over wireless networks - a distributed optimization approach (2010)

We focus on a particular form of network coding, reverse carpooling, in a wireless network where the potentially coded transmitted messages are to be decoded immediately upon reception. The network is fixed and known, and the system performance is measured in terms of the number of wireless broadcasts required to meet multiple unicast demands. Motivated by the structure of the coding scheme, we formulate the problem as a linear program by introducing a flow variable for each triple of connected nodes. This allows us to have a formulation polynomial in the number of nodes. Using dual decomposition and projected subgradient method, we present a decentralized algorithm to obtain optimal routing schemes in presence of coding opportunities. We show that the primal sub-problem can be expressed as a shortest path problem on an edge-graph, and the proposed algorithm requires each node to exchange information only with its neighbors.
Biologically Inspired Vapor-Diffusion Route to Metal Hydroxide Films at Low Temperatures: Synthesis, Conversion and Applications (2006)

Nanostructured thin films have been prepared using a kinetically controlled vapor-diffusion method of catalysis at low temperature. Vectorial control by diffusion of a base catalyst into an aqueous metal salt solution yields metal hydroxide films with unique structures. Post-synthesis treatment of these materials yielded more stable metal oxide films. All films were characterized using X-ray powder diffraction, scanning electron microscopy and a wide rage of chemical and electrochemical methods.
New results on the performance of MT-DS-SS in the presence of phase noise (2005)

Multicarrier (MC) modulation and code-division multiple access (CDMA) schemes have seen much recent attention for the high capacities and flexibility they can provide. A potential difficulty with these systems is their sensitivity to the effects of imperfect orthogonality among subcarriers caused by imperfect frequency up/down conversion due to phase noise. In this work, we provide a general method to upper bound and/or approximate system performance in multitone direct-sequence spread spectrum (MT-DS-SS) signaling in the presence of phase noise, and improve on prior work. We model phase noise as a slow random process with small variance. We assume coherent detection with BPSK modulation and use a phase noise model based upon one for a practical phase-locked loop (PLL). Comparisons between simulations and analysis show excellent agreement, and also show that performance degradation is dominated by the common phase noise, and that the intercarrier interference (ICI) contribution is very small. Our analytical/numerical method is useful for performance evaluation when the target error probability values are of the order of 10/sup -6/ or lower, and can also be easily applied to any multicarrier system with other phase noise models.
ChemInform Abstract: Total Synthesis of (+)‐Papuamine (VII): An Antifungal Pentacyclic Alkaloid from a Marine Sponge, Haliclona sp. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Comparing Simulation, Emulation, and Real-World Experimental Results in Mobile Ad hoc Networks (2006)

We compare the major MANET protocols, AODV, DSR and OLSR, using a set of the same scenarios recreated in simulation, emulation and real world. The purpose of this is twofold:
1. To explore the util ...
Perioperative Change in Cervical Lordosis and Health-Related Quality-of-Life Outcomes (2022)

Background Surgeons have scrutinized spinal alignment and its impact on improving clinical outcomes following anterior cervical discectomy and fusion (ACDF). The primary analysis of this study examines the relationship between change in perioperative cervical lordosis (CL) and health-related quality-of-life (HRQOL) outcomes after ACDF. Secondary analysis evaluates the effects of fusion construct length on outcomes in patients grouped by preoperative cervical alignment. Methods A retrospective cohort study was performed on an institutional database including patients who underwent 1- to 3-level ACDF. C2-C7 CL was measured preoperatively and at final follow-up. For primary analysis, patients were classified based on their perioperative cervical lordotic correction: (1) kyphotic, (2) maintained, and (3) restored. For secondary analysis, patients were categorized based on their preoperative C2-C7 CL: (1) kyphotic, (2) neutral, and (3) lordotic. Demographics and perioperative change in patient-reported outcome measures were compared between groups. Results A total of 308 patients were included. A significant difference was noted among maintained, restored, and kyphotic groups in terms of delta physical compositeshort form-12 score (ΔPCS-12) (9.0 vs 10.3 vs 1.5; P = 0.04) and delta visual analog scale score (ΔVAS) for arm pain (−0.9 vs −3.8 vs −0.6; P = 0.03). Regression analysis revealed significantly greater improvement of PCS-12 (β: 8.6; P = 0.03) and VAS arm (β: −2.0; P = 0.03) scores in restored patients compared with kyphotic patients. The length of fusion construct in patients grouped by preoperative cervical alignment had no significant impact on the clinical outcomes on regression analysis. Conclusions Significantly greater PCS-12 and VAS arm improvement were seen in patients whose cervical sagittal alignment was restored to neutral/lordotic compared with those who remained kyphotic. Multivariate analysis demonstrated no association between construct length and perioperative outcomes. Clinical Relevance The results of this study highlight the importance of sagittal alignment and restoration of CL after short-segment ACDF. Irrespective of preoperative sagittal alignment, the length of ACDF fusion construct does not have a significant impact on clinical outcomes. Level of Evidence 3.
In Vitro Splicing Assays (2012)

In vitro splicing assays represent an important technique to analyze, in detail, the basic splicing mechanisms for a pre-mRNA of interest. The cell-free assays, under defined conditions, have many advantages for characterizing the cis-acting elements and trans-acting factors responsible for the regulation of alternative splicing. Radiolabeled transcripts of minigenes of interest are spliced in HeLa cell nuclear extracts under various conditions, and the splicing products analyzed directly using denaturing polyacrylamide gel electrophoresis, or detected indirectly using RT-PCR. Here, a standard method of in vitro splicing is described that has been used successfully for many years in the authors' laboratories.