gebhart/patrepeval huggingface dataset:
Lattice strain and ferromagnetism in pure and substituted BiFeO[sub 3] samples (2013)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation T. Karan, S. Ram; Lattice strain and ferromagnetism in pure and substituted BiFeO3 samples. AIP Conf. Proc. 3 June 2013; 1536 (1): 971–972. https://doi.org/10.1063/1.4810555 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
A New Bipolar Imaging Device (BASIS) (1989)

A bipolar imaging device consisting of a capacitor loaded emitter follower circuit for a photo-transistor has been implemented into linear image sensors, which has capabilities of charge amplification and self-noise-reduction. The linear sensors are demonstrated experimentally to exhibit excellent performance such as a linearity in a wide dynamic range and a high sensitivity.
T Helper Cell Responses (1990)

Efforts in our laboratories have been directed toward the identification of antigenic sites of human immunodeficiency virus (HIV) proteins capable of eliciting T cell immunity. Evidence from a number of laboratories suggests an important role for an intact functional T cell response in combating HIV infection [1-11]. Helper T cells are required for optimal cytotoxic T cell responses to kill virus-infected cells as well as for antibody responses to protein antigens. T cell proliferation and Interleukin 2 (IL-2) production represent the most convenient general methods for assessing helper T cells of the CD4+ phenotype, which generally recognize antigen in association with class II major histocompatibility complex (MHC) molecules on the antigen-presenting cell or the B cell to be helped. Attempts to enhance the T cell response by immunizing individuals with the relevant T cell sites from the viral proteins may therefore prove a significant measure in altering the course of an HIV infection. The rational design of synthetic or recombinant fragment vaccines is dependent on identification of such T cell epitopes. Furthermore, T cell help may develop before an antibody response is detectable. Therefore, T cell proliferation to HIV antigens may represent a diagnostic test that could detect exposure or infection before antibody seroconversion. Finally, because the loss of T cell proliferative response to soluble protein antigens is one of the first detectable events in the development of immunodeficiency, long before any clear decline in total CD4+ T cell numbers [12,13], T cell proliferation may be a valuable prognostic test for following the course of HIV infection.
Presence of a new microtubule cold-stabilizing factor in bull sperm dynein preparations (1990)

Brain tubulin polymerized with dynein isolated from bull spermatozoa forms cold-stable microtubules, in contrast with microtubules made of brain tubulin polymerized by brain microtubule-associated proteins (MAPs). The level of cold-stable microtubules depends on the concentration of dynein used. Addition of dynein to cold-unstable microtubules renders these microtubules stable to cold. Although ATP and a non-hydrolysable ATP analogue increase the formation of microtubules made of tubulin and dynein, these nucleotides have no effect on dynein cold-stabilizing properties. The data suggests that a new factor, not involving the dynein ATPase active site and present in bull sperm dynein preparations, confers cold-stability to microtubules.
Strategic Design and Synthesis of Osmium(II) Complexes Bearing a Single Pyridyl Azolate π-Chromophore:  Achieving High-Efficiency Blue Phosphorescence by Localized Excitation (2007)

We present the strategic design and synthesis of Os(II) complexes bearing a single pyridyl azolate pi-chromophore with an aim to attain high efficiency blue phosphorescence by way of localized transition. It turns out that our proposal of localized excitation seems to work well upon anchoring a single pi-chromophore on the Os(II) complexes such that the control of MLCT versus pipi* (or even LLCT) transitions is more straightforward. Among the titled complexes, [Os(CO)3(tfa)(fppz)] (1) and [Os(CO)3(tfa)(fbtz)] (5) (tfa=trifluoroacetate, (fppz)H=3-(trifluoromethyl)-5-(2-pyridyl)pyrazole, and (fbtz)H=3-(trifluoromethyl)-5-(4-tert-butyl-2-pyridyl)-1,2,4-triazole) give the anticipated blue phosphorescence with efficiencies of 0.26 (lambdamax=460 nm) and 0.27 (lambdamax=450 nm), respectively. For their halide analogues [Os(CO)3(X)(fppz)] (2, X=Cl; 3, X=Br; 4, X=I) and phosphine-substituted isomeric derivatives [Os(tfa)(fppz)(PPh2Me)2(CO)] (6-8), the localization of the excitation energy seems to populate at certain vibrational modes with weak bonding strength and hence an associated shallow potential energy surface to induce a facile radiationless transition. Furthermore, their ancillary ligands play an important role in fine-tuning not only the energy gap but also the emission intensity, i.e., in manifesting the radiationless transition pathways. Our results clearly show that there is always a tradeoff upon varying the parameters in an aim to optimize the hue and efficiency of phosphorescence toward blue.
Novel 7-(dimethylamino)fluorene-based fluorescent probes and their binding to human serum albumin (2009)

A novel solvatochromic fluorescent molecule, 9,9-dibutyl-7-(dimethylamino)-2-fluorenesulfonate 2 was synthesized from 2-nitrofluorene in moderate yield. The fluorescence spectra of 2 and 7-(dimethylamino)-2-fluorenesulfonate 1 shift to shorter wavelengths as the polarity of the medium decreases. Both 1 and 2 bind to hydrophobic sites of human serum albumin (HSA). The apparent binding constants were determined by fluorescence titration to be 0.37 x 10(6) M(-1) for 1 and 2.2 x 10(6) M(-1) for 2. The energy of the Trp-214 fluorescence of HSA is transferred to the HSA-bound fluorophores with near 100% efficiency. The covalent bonding of acrylodan (AC) to Cys-34 has little effect on the binding affinity of 2 to HSA or fluorescent behavior of HSA-bound 2. Bound 2 also has little effect on the fluorescence of AC, but 2-->AC and Trp-214-->2-->AC resonance energy transfers were observed. Competitive binding between the fluorene compounds and other ligands such as 1-anilino-8-naphthalenesulfonate, aspirin, S-(+)-ibuprofen and phenylbutazone were also studied fluorometrically. The results indicated that the primary binding site of 2 to HSA is site II in domain IIIA, whereas 1 binds to site I in domain IIA, but a different region from the phenylbutazone binding site. Because of its large molar absorptivity, strong fluorescence, sensitivity to its environment, and high binding constant to HSA, 2 can be used successfully in the study of proteins and their binding properties.
Density, 1 Meter Long Plasma for Accelerator Applications (2001)

Uniform, high density plasmas on the order of a few meters in length are needed for the next generation of plasma based particle accelerator boosters. Such plasmas are currently beyond the state of the art. In this poster, we present the results of a feasibility study for producing a one meter long, uniform plasma with a density of 10 16 cm -3
TRAFFIC NOISE BARRIER SYSTEM: U.S. Patent No. US 7,220,077 B2 (2007)

A crashworthy traffic noise barrier system for use alongside a path of traffic, the crashworthy traffic noise barrier system comprises a crashworthy longitudinal barrier extending substantially parallel to the path of traffic and a crashworthy traffic noise barrier wall supported by the longitudinal barrier. The crashworthy traffic noise barrier wall includes a plurality of upstanding posts attached to the traffic noise barrier wall, at least one panel supported between each adjacent pair of posts in the plurality of upstanding posts, and at least one longitudinal beam spaced above a top surface of the longitudinal barrier and extending across the plurality of upstanding posts for redirecting a portion of an errant vehicle away from the at least one panel. The longitudinal beams redirect energy of the errant vehicle away from the panels such that the panels and any fragments of the panels, remain attached to the traffic noise barrier wall. The panels may be transparent and may be reinforced with plastic bands, plastic threads, or a plastic net.
Role of multiparton interactions on J/ψ production in p+p collisions at LHC energies (2018)

The production mechanism of quarkonia states in hadronic collisions is still to be understood by the scientific community. In high-multiplicity $p+p$ collisions, underlying event observables are of major interest. The multiparton interactions (MPIs) are underlying event observables, in which several interactions occur at the partonic level in a single $p+p$ event. This leads to dependence of particle production on event multiplicity. If the MPI occurs in a harder scale, there will be a correlation between the yield of quarkonia and total charged-particle multiplicity. The ALICE experiment at the LHC in $p+p$ collisions at $\sqrt{s}=7$ and 13 TeV has observed an approximate linear increase of relative $J/\ensuremath{\psi}$ yield, ($\frac{d{N}_{J/\ensuremath{\psi}}/dy}{⟨d{N}_{J/\ensuremath{\psi}}/dy⟩}$), with relative charged-particle multiplicity density, ($\frac{d{N}_{\text{ch}}/dy}{⟨d{N}_{\text{ch}}/dy⟩}$). In our present work, we have performed a comprehensive study of the production of charmonia as a function of charged-particle multiplicity in $p+p$ collisions at LHC energies using the perturbative QCD--inspired multiparton interaction model, pythia8 tune 4C, with and without the color reconnection scheme. A detailed multiplicity and energy-dependent study is performed to understand the effects of MPI on $J/\ensuremath{\psi}$ production. The ratio of $\ensuremath{\psi}(2S)$ to $J/\ensuremath{\psi}$ is also studied as a function of charged-particle multiplicity at LHC energies.
Large Format Multifunction 2-Terabyte Optical Disk Storage System (1996)

The Kodak Digital Science OD System 2000E automated disk library (ADL) base module and write-once drive are being developed as the next generation commercial product to the currently available System 2000 ADL. Under government sponsorship with the Air Force's Rome Laboratory, Kodak is developing magneto-optic (M-O) subsystems compatible with the Kodak Digital Science ODW25 drive architecture, which will result in a multifunction (MF) drive capable of reading and writing 25 gigabyte (GB) WORM media and 15 GB erasable media. In an OD system 2000 E ADL configuration with 4 MF drives and 100 total disks with a 50% ration of WORM and M-O media, 2.0 terabytes (TB) of versatile near line mass storage is available.
Abstract 2440: CD47 is a prognostic factor and an antibody target that synergizes with rituximab to eradicate non-Hodgkin lymphoma (2010)

Abstract Monoclonal antibodies are standard therapeutics for several cancers including the anti-CD20 antibody rituximab for B cell non-Hodgkin lymphoma (NHL). Rituximab and other antibodies are not curative, and must be combined with cytotoxic chemotherapy for clinical benefit. Here we identify CD47 as an attractive monoclonal antibody target in NHL. A major function of CD47 is to inhibit phagocytosis, through binding its receptor, SIRP-alpha, on phagocytes. We hypothesize that NHL cells over-express CD47 to evade immune phagocytosis and that blockade of CD47 signaling by a monoclonal antibody can eliminate NHL cells by enabling phagocytic engulfment. Here we investigate the therapeutic potential of an anti-CD47 antibody alone and in combination with rituximab for the treatment of NHL. We predict that the combination of anti-CD47 antibody and rituximab through utilization of two independent antibody mechanisms will result in synergistic phagocytosis and elimination of NHL cells. We found that CD47 protein is highly expressed on primary human NHL cells compared to normal B cell counterparts. Higher CD47 gene expression predicted an inferior outcome in several cohorts of NHL patients, providing independent prognostic value. Blocking anti-CD47 antibodies preferentially enabled phagocytosis of NHL cells but not normal cell counterparts in vitro while the combination of anti-CD47 antibody and rituximab resulted in synergistic phagocytosis of NHL cells. In vivo, anti-CD47 antibody treatment of human NHL-engrafted mice reduced lymphoma burden and prolonged survival compared to IgG control treatment. Furthermore, anti-CD47 antibody treatment in combination with rituximab led to elimination of lymphoma and cure of NHL-engrafted mice compared to either antibody treatment as a single agent. The above in vivo results were observed in both a disseminated and localized human NHL cell line mouse model as well as in primary human lymphoma xenotransplants. These antibodies synergized through a novel mechanism combining Fc receptor (FcR)-dependent and FcR-independent stimulation of phagocytosis that might be applicable to many other cancers. Together, these data provide the rationale for utilizing an anti-CD47 antibody either alone or in combination with rituximab in treating human NHL. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 101st Annual Meeting of the American Association for Cancer Research; 2010 Apr 17-21; Washington, DC. Philadelphia (PA): AACR; Cancer Res 2010;70(8 Suppl):Abstract nr 2440.
Continuous-flow total heart replacement device implanted in a 55-year-old man with end-stage heart failure and severe amyloidosis. (2012)

We implanted a continuous-flow total heart replacement device in a 55-year-old man who had severe end-stage heart failure due to amyloidosis and no other options for treatment. The device was composed of 2 modified HeartMate II ventricular assist pumps. After the implantation, our patient recovered normal neurologic function and was able to converse with his family and work on his computer. He died of multisystem organ failure caused by severe amyloidosis 5 weeks after the implantation. During the past 6 years, we have been developing and testing various technological iterations for total heart replacement in our animal laboratory and have achieved survival periods as long as 90 days in calves. We describe the development, preclinical trials, and adaptation for human use of the modified HeartMate II apparatus, as well as its role in our patient's survival.
Wearable Soft Microtube Sensors for Quantitative Home-Based Erectile Dysfunction Monitoring (2022)

Quantifiable erectile dysfunction (ED) diagnosis involves the monitoring of rigidity and tumescence of the penile shaft during nocturnal penile tumescence (NPT). In this work, we introduce Erectile Dysfunction SENsor (EDSEN), a home-based wearable device for quantitative penile health monitoring based on stretchable microtubular sensing technology. Two types of sensors, the T- and R-sensors, are developed to effectively measure penile tumescence and rigidity, respectively. Conical models mimicking penile shaft were fabricated with polydimethylsiloxane (PDMS) material, using different base to curing agent ratios to replicate the different hardness properties of a penile shaft. A theoretical buckling force chart for the different penile models is generated to determine sufficiency criteria for sexual intercourse. An average erect penile length and circumference requires at least a Young's modulus of 179 kPa for optimal buckling force required for satisfactory sexual intercourse. The conical penile models were evaluated using EDSEN. Our results verified that the circumference of a penile shaft can be accurately measured by T-sensor and rigidity using the R-sensor. EDSEN provides a private and quantitative method to detect ED within the comfortable confines of the user's home.
Expression of the chemokine RANTES by a human bronchial epithelial cell line. Modulation by cytokines and glucocorticoids (1995)

The chemokine RANTES is a potent chemoattractant for eosinophils, lymphocytes, and monocytes, and has been detected recently in the epithelium of human airways mucosa. We have studied, therefore, the expression of RANTES mRNA and protein in the human bronchial epithelial cell line BEAS-2B. Using Northern blot analysis, RANTES mRNA was not detectable in unstimulated BEAS-2B cells. Incubation of cells with TNF-alpha or IFN-gamma induced the expression of RANTES mRNA and protein within 16 h. The combination of TNF-alpha and IFN-gamma displayed a marked synergism in inducing RANTES expression. Pretreatment of cells with the glucocorticoid budesonide (10(-10)-10(-7) M) for 24 h inhibited expression of RANTES mRNA and protein stimulated by either TNF-alpha or TNF-alpha plus IFN-gamma in a concentration- and time-dependent manner. Nonglucocorticoid steroids did not inhibit RANTES mRNA expression. Production of RANTES by epithelium could contribute to the mechanism of selective cellular recruitment occurring in the airways during inflammation, thus playing a relevant role in the pathogenesis of diseases such as asthma, rhinitis, and polyposis. The down-regulation of RANTES production by glucocorticoids in epithelial cells may contribute to the efficacy of these compounds in reducing cellular infiltration and, ultimately, to their anti-inflammatory properties.
On-demand cooperation with power control: Protocol and experimental results (2011)

In cooperative communications, wireless devices pool their resources to increase overall reliability. However, devices that would normally be idle spend energy to help neighbors. This altruism is a source of much debate on the efficacy of cooperative communications. In this work, we present the Power-controlled Distributed On-demand Cooperation (PDOC) protocol, which employs cooperative relays in an energy efficient manner. PDOC provides significant reduction in energy usage at cooperative relays in two key regimes: when relays are close to destination nodes and when they are far away. In this work, we describe PDOC and evaluate the protocol with a real-time FPGA implementation and associated characterization.
A Reactive Tabu Search Based Equalizer for Severely Delay-Spread UWB MIMO-ISI Channels (2009)

We propose a novel equalizer for ultra wideband (UWB) multiple-input multiple-output (MIMO) channels characterized by severe delay spreads. The proposed equalizer is based on reactive tabu search (RTS), which is a heuristic originally designed to obtain approximate solutions to combinatorial optimization problems. The proposed RTS equalizer is shown to perform increasingly better for increasing number of multipath components (MPC), and achieve near maximum likelihood (ML) performance for large number of MPCs at a much less complexity than that of the ML detector. The proposed RTS equalizer is shown to perform close to within 0.4 dB of single-input multiple-output AWGN performance at 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-3</sup> uncoded BER on a severely delay-spread UWB MIMO channel with 48 equal-energy MPCs.
Microencapsulation-protectedl-ascorbic acid for the application of human epithelial HaCaT cell proliferation (2014)

l-ascorbic acid is an abundant water-soluble nutrient found in vegetables and fruits. It enhances the cell proliferation, which is helpful in wound healing process. However, it is relatively unstable and easily degraded under external environments including acidity, alkalinity, evaporation, heat, oxidization, light or moisture. Its storage remains challenged. This study reported the development of l-ascorbic acid microcapsules using the natural protein, gelatin, and the natural polysaccharide, agar, as the wall protection carrier. The physical properties including entrapment efficiency, particle size, surface morphology, chemical compositions and release profile were identified. The cell proliferation of l-ascorbic acid microcapsules was stronger than the free drug. Significant cell growth in microencapsulated l-ascorbic acid-treated human epithelial HaCaT cells was observed when compared with untreated control. Since cell proliferation and wound repair are closely related, it is believed that l-ascorbic acid microcapsules would effectively increase the potential effect of wound healing activity in human skin.
A Practical Synthesis of a Potent and Selective Diacylglycerol Acyltransferase-1 (DGAT-1) Inhibitor (2014)

A practical synthesis of a potent, selective, and orally efficacious diacylglycerol acyltransferase-1 (DGAT-1) inhibitor, is described. This synthesis is suitable for multi-kilogram scale with high regioselectivity and stereoselectivity. The synthesis involves a Knoevenagel condensation with Meldrum’s acid followed by the stereoselective addition of phenyl cuprate, regioselective Friedel–Crafts acylation, cyclization, and a regioselective reduction through an enol triflate with catalytic platinum oxide to provide the desired compound in 5.2% yield over 12 steps.
Micro RNA dysregulation in cancer: diagnostics, monitoring and therapeutics. A comprehensive review (2017)

This article, published in the March 2012 issue of EMBO Molecular Medicine, contained text passages similar to those from a number of previous publications, many by the same authors: “Cancer microRNAs: from subtype profiling to predictors of response to therapy” by Chan E, Pardo DE, Weidhaas JB in Trends Mol Med 17: 235–243; “Targeting microRNAs in cancer: rationale, strategies and challenges” by Garson R, Marcucci G, Croce CM in Nat Rev Drug Discov 9: 775–789; “MicroRNAs in cancer: small molecules with a huge impact” by Iorio MV, Croce CM in J Clin Oncol 27: 5848–5856; and “Breast cancer and microRNAs: therapeutic impact” by Iorio MV, Casalini P, Piovan C, Braccioli L, Tagliabue E in Breast 20 Suppl. 3: S63–S70. Formal citations to the original articles were inadvertently omitted. Similarly, a number of later publications overlap with text from this reference without formal citations. These are as follows: “microRNA: new players in metastatic process” by Triulzi T, Iorio MV, Tagliabue E, Casalini P in Oncogene and cancer—from bench to clinic, Siregar Y (ed.), Chapter 16. Rijeka: InTech; “microRNA involvement in human cancer” by Iorio MV, Croce CM in Carcinogenesis 33: 1126–1133; and “Causes and consequences of microRNA dysregulation” by Iorio MV, Croce CM in Cancer J, 18: 215–222. The authors apologize for this oversight.