gebhart/patrepeval huggingface dataset:
Texture characterization of high T sub c thick films (1990)

The anisotropic properties which exist in all high-{Tc} compounds make it necessary to characterize the preferred orientation (or texture) of crystals which results from various processing methods. Once a suitable preferred orientation is achieved, a significant increase in performance is anticipated. In this study, thick films ({approximately}80 {mu}m) of Bi-Sr-Ca-Cu-O (BSCCO) on silver substrates were characterized by pole figure techniques to obtain an Orientation Distribution Function (ODF). 6 refs., 5 figs.
<title>Multilayered holographic memory: a two-dimensional case</title> (1998)

The multilayered structure of the data storage is considered for the 2D multichannel holographic memory. The influence of the number of layers on the signal to noise ratio at the photodetector is estimated for the different diffraction efficiencies and number of channels. The comparison is made with the 1D case. The use of the random distribution of the initial phases in the channels during the recording is proposed for the diminishing of the intermodulation noises during the reconstruction. It is shown that the 2D holograms are more preferable than the 1D, as they enable greater capacity increase by adding more layers for the same requirements to the readout quality.
Caged Phospho-Amino Acid Building Blocks for Solid-Phase Peptide Synthesis (2003)

Three 1-(2-nitrophenyl)ethyl-caged phospho-amino acids have been synthesized for use in standard N(alpha)-fluorenylmethoxycarbonyl-based solid-phase peptide synthesis (SPPS). The most common naturally occurring phospho-amino acids, serine, threonine, and tyrosine, were prepared as protected caged building blocks by modification with a unique phosphitylating reagent. In previous work, caged phospho-peptides were made using an interassembly approach (Rothman, D. M.; Vazquez, M. E.; Vogel, E. M.; Imperiali, B. Org. Lett. 2002, 4, 2865-2868). However, this technique is limited to creating peptides without oxidation sensitive residues C-terminal to the amino acid to be modified and the methodology involves synthetic manipulations on the solid phase that may limit the utilization of the methodology. Herein we report the facile synthesis of N-alpha-Fmoc-phospho(1-nitrophenylethyl-2-cyanoethyl)-L-serine 1, N-alpha-Fmoc-phospho(1-nitrophenylethyl-2-cyanoethyl)-L-threonine 2, and N-alpha-Fmoc-phospho(1-nitrophenylethyl-2-cyanoethyl)-L-tyrosine 3. These building blocks allow the synthesis of any caged phospho-peptide sequence using standard Fmoc-based SPPS procedures.
Efficient End-to-End QoS supporting algorithm in NGN using optimal flows and measurement feed-back for NGN (2006)

This paper proposes an efficient end-to-end QoS supporting mechanism in Next Generation Network (NGN) with heterogeneous QoS capability. By showing optimal flows in heterogeneous QoS capability network, NGN can support average delay of end-to-end.
RNA binding protein Caprin-2 is a pivotal regulator of the central osmotic defense response (2015)

In response to an osmotic challenge, the synthesis of the antidiuretic hormone arginine vasopressin (AVP) increases in the hypothalamus, and this is accompanied by extension of the 3' poly(A) tail of the AVP mRNA, and the up-regulation of the expression of RNA binding protein Caprin-2. Here we show that Caprin-2 binds to AVP mRNAs, and that lentiviral mediated shRNA knockdown of Caprin-2 in the osmotically stimulated hypothalamus shortens the AVP mRNA poly(A) tail at the same time as reducing transcript abundance. In a recapitulated in vitro system, we confirm that Caprin-2 over-expression enhances AVP mRNA abundance and poly(A) tail length. Importantly, we show that Caprin-2 knockdown in the hypothalamus decreases urine output and fluid intake, and increases urine osmolality, urine sodium concentration, and plasma AVP levels. Thus Caprin-2 controls physiological mechanisms that are essential for the body's response to osmotic stress.
Distributed Pulse Rotary Traveling Wave VCO: Architecture and Design (2019)

This paper describes the architecture and design of pulse rotary traveling wave voltage controlled oscillators that preserve wave shape, and thus wave harmonics using non-linear amplification. These oscillators can provide multiple low dutycycle clock phases and architectural modifications can allow for the same clock phase to be present at multiple physical locations. A design fabricated in GFUS 130nm (8RF) technology operates at 5.32 GHz with a 10 MHz offset phase noise of -128.15 dBc/Hz at 45.4 mW while generating 12 driven phase outputs with 15.66 ps phase resolution and less than 500 fs cycle-to-cycle jitter. It can be coarse or fine tuned within a frequency range of 4.35 GHz to 5.4 GHz with KV CO of 1.7 GHz/V and 470 MHz/V respectively. The start-up mechanism of the oscillator minimizes transmission line reflections and allows maintenance of the traveling wave shape, yielding an average 3 dB figure of merit improvement over existing designs.
Flexible Aliphatic–Aromatic Polyamide Thin Film Composite Membrane for Highly Efficient Organic Solvent Nanofiltration (2020)

Membranes with strong solvent resistance and efficient molecular separation are desirable in industries. Especially the fractionation of organic molecules in harsh organic solvents still remains a challenge in the pharmaceutical industry. Here, we report a flexible aliphatic–aromatic polyamide thin-film composite (TFC) membrane with high stability, permeability, and precise selectivity in mild solvents as well as in polar aprotic solvents. This composite organic solvent nanofiltration (OSN) membrane integrates a cross-linked sub-100 nm nanofilm and a nanofibrous sublayer. The flexible aliphatic chains in the polyamide network render the selective layer with a tunable free volume in different organic solvents. Consistent with the solvent swelling degrees, the membrane shows a cutoff in a sequence of dimethyl sulfoxide (DMSO, MWCO: 814 g mol–1) > N,N-dimethylformamide (DMF, MWCO: 648 g mol–1) > methanol (MWCO: 506 g mol–1, with DMF activation) > methanol (MWCO: 327 g mol–1). The membrane can precisely fractionate two molecules with difference in molar mass of <166 g mol–1 in a polar aprotic solvent, DMSO. Long-term filtration tests in DMF further demonstrate that the TFC membrane has an outstanding chemical stability and molecular selectivity in aggressive organic media. This work provides an efficient way to control OSN membrane separations by introducing flexible alkane chains into the rigid polymer structure followed by solvent activation. Additionally, the high permeance and excellent separation efficiency of the TFC membrane highlight its great potential for molecular separation in pharmaceutical and chemical industries.
A simplified motion estimation using an approximation for the MPEG-2 real-time encoder (2002)

We propose a simplified motion estimation method which provides motion vectors for all types of motion compensation used in MPEG-2. The method is a result of applying a newly introduced approximation to the canonical three-step method described in the MPEG-2 Test Model. It reduces the number of necessary computations in the second and the third steps to less than 1%, and that of data transfers to about 8% of the canonical method. Total complexity of the proposed method is nearly that of the full-pel search motion estimation.
Development of an Automated Sample Injection System for Pillar Array Columns (2019)

A pillar array column with a perfectly ordered internal structure has a higher separation efficiency than a particle-packed column used in conventional high-performance liquid chromatography. However, applying the pillar array column technology to quantitative analysis is challenging as the injection volume of the sample varies for each injection. This occurs because the sample volumes are in the order of nanoliters and the sample is injected manually. In this study, an automated sample injection system was developed to solve this problem. The system was composed of two pumps (one for the sample and other for the mobile phase), a six-way valve that can be controlled by a PC, and an autosampler. The peak height deviation, which is more than 20% in the conventional manual injection system, was improved to 1.2% and 0.4% for the two coumarin dye samples. This result indicated that the automated sample injection method developed in this study could be applied to pillar array columns to allow for quantitative analysis.
Generic Multicast Router Election on LAN's (2016)

When a host is connected to multiple multicast capable routers, each
of these routers is a candidate to process the multicast flow for that
LAN, but only one router should be elected to process it. This
document proposes a generic multicast router election mechanism using
Internet Group Management Protocol (IGMP) and Multicast Listener
Discovery (MLD) that can be used by any Multicast Overlay Signalling
Protocol (MOSP). Having such generic election mechanism removes a
dependency on Protocol Independent Multicast (PIM).
A composable service model for lossy network elements (2002)

The development of scalable service models for integrated services networks is crucial for fostering interoperability and competition among multiple network service providers that support quality of service. A key scalability property of a service model is composability, which allows models for network elements in tandem to be lumped together into a composite model which is of the same type as the constituent service models. We present a new service model for lossy network elements, and show that it is composable. To illustrate the new service model, we characterize some fundamental network elements in terms of it.
Crystal Structure of the Catalytic Domain of a Botulinum Neurotoxin Homologue from Enterococcus faecium: Potential Insights into Substrate Recognition (2023)

<i>Clostridium botulinum</i> neurotoxins (BoNTs) are the most potent toxins known, causing the deadly disease botulism. They function through Zn<sup>2+</sup>-dependent endopeptidase cleavage of SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) proteins, preventing vesicular fusion and subsequent neurotransmitter release from motor neurons. Several serotypes of BoNTs produced by <i>Clostridium botulinum</i> (BoNT/A-/G and/X) have been well-characterised over the years. However, a BoNT-like gene (homologue of BoNT) was recently identified in the non-clostridial species, <i>Enterococcus faecium,</i> which is the leading cause of hospital-acquired multi-drug resistant infections. Here, we report the crystal structure of the catalytic domain of a BoNT homologue from <i>Enterococcus faecium</i> (LC/En) at 2.0 Å resolution. Detailed structural analysis in comparison with the full-length BoNT/En AlphaFold2-predicted structure, LC/A (from BoNT/A), and LC/F (from BoNT/F) revealed putative subsites and exosites (including loops 1-5) involved in recognition of LC/En substrates. LC/En also appears to possess a conserved autoproteolytic cleavage site whose function is yet to be established.
Opportunities brought by sequential 3D CoolCube™ integration (2016)

3D VLSI with a CoolCube™ monolithic integration flow allows vertically stacking several layers of devices with a unique connecting via density above tens of million/mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . This results in increased devices density and gains in power and performance thanks to wire-length reduction without the extra cost associated to transistor scaling. In addition to power saving, this true 3D integration opens perspectives in terms of heterogeneous integration. We will review the opportunities brought by CoolCube™ and will present the most advanced technological demonstration of 3D CMOS over CMOS CoolCube™ integration.
Supplementary Figure 1 from Regulation of CD4<sup>+</sup>NKG2D<sup>+</sup> Th1 Cells in Patients with Metastatic Melanoma Treated with Sorafenib: Role of IL-15Rα and NKG2D Triggering (2023)

&lt;p&gt;PDF file - 25K, Schedule of the sorafenib and temozolomide combination regimen.&lt;/p&gt;
Treatment with lecinoxoids attenuates focal and segmental glomerulosclerosis development in nephrectomized rats (2018)

Focal segmental glomerulosclerosis (FSGS) is a scarring process associated with chronic low-grade inflammation ascribed to toll-like receptor (TLR) activation and monocyte migration. We developed synthetic, small-molecule lecinoxoids, VB-201 and VB-703, that differentially inhibit TLR-2- and TLR-4-mediated activation and monocyte migration. The efficacy of anti-inflammatory lecinoxoid treatment on FSGS development was explored using a 5/6 nephrectomy rat model. Five-sixths of nephrectomized rats were treated with lecinoxoids VB-201, VB-703 or PBS, for 7 weeks. Upon sacrifice, albumin/creatinine ratio, glomerulosclerosis, fibrosis-related gene expression and the number of glomerular and interstitial monocyte were evaluated. Treatment of nephrectomized rats with lecinoxoids ameliorated glomerulosclerosis. The percentage of damaged glomeruli, glomerular sclerosis and glomeruli fibrotic score was significantly reduced following VB-201 and VB-703 treatment. VB-703 attenuated the expression of fibrosis hallmark genes collagen, fibronectin (FN) and transforming growth factor β (TGF-β) in kidneys and improved albumin/creatinine ratio with higher efficacy than did VB-201, but only VB-201 significantly reduced the number of glomerular and interstitial monocytes. These results indicate that treatment with TLR-2, and more prominently, TLR-4 antagonizing lecinoxioids, is sufficient to significantly inhibit FSGS. Moreover, inhibiting monocyte migration can also contribute to treatment of FSGS. Our data demonstrate that targeting TLR-2-TLR-4 and/or monocyte migration directly affects the priming phase of fibrosis and may consequently perturb disease parthogenesis.
Disambiguation of super parts of speech (or supertags) (1994)

In a lexicalized grammar formalism such as Lexicalized Tree-Adjoining Grammar (LTAG), each lexical item is associated with at least one elementary structure (supertag) that localizes syntactic and semantic dependencies. Thus a parser for a lexicalized grammar must search a large set of supertags to choose the right ones to combine for the parse of the sentence. We present techniques for disambiguating supertags using local information such as lexical preference and local lexical dependencies. The similarity between LTAG and Dependency grammars is exploited in the dependency model of supertag disambiguation. The performance results for various models of supertag disambiguation such as unigram, trigram and dependency-based models are presented.
Molecular cytogenetic analysis of medulloblastomas and supratentorial primitive neuroectodermal tumors by using conventional banding, comparative genomic hybridization, and spectral karyotyping (2000)

The combined results indicate that chromosomes 7 and 17 are the most frequently rearranged chromosomes (10.1% and 8.9%, respectively, in all rearrangements detected). Furthermore, chromosomes 3 (7.8%), 14 (7%), 10 (6.7%), and 22 (6.5%) were also found to be frequently rearranged, followed by chromosomes 6 (6.5%), 13 (6.2%), and 18 (6.2%). Eight (33%) of 24 tumors exhibited high-level gains or gene amplification. Amplification of MYCN was identified in four tumors, whereas amplification of MYCC was identified in one tumor. One tumor exhibited a high-level gain of chromosome 9p. Additionally, desmoplastic medulloblastomas and large-cell medulloblastomas exhibited higher karyotype heterogeneity, amplification, and aneusomy than classic medulloblastomas.
Edge-curling-wall discontinuities and interactions with Bloch walls in easy-axis Permalloy (1988)

Laminations of soft-magnetic and nonmagnetic films, which meet the criteria for easy-axis state, have edge-curling walls instead of the triangular closure domains of single sheets. A laser magnetooptic microscope has been used to image and model two types of edge-curling wall discontinuities that are induced by geometry in finite elements. One is a sectored-vortex discontinuity in a single-domain state that was not previously predicted. In addition, laminates with Permalloy layers on the order of 1- mu m thick are usually divided into easy-axis domains by 180 degrees Bloch walls. Several types of interaction of a Bloch wall with an edge-curling wall are described. The existence of coupled (top and bottom layers) single-domain states in two-magnetic-layer elements is confirmed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Energy-Based Adaptive Focusing: Optimal Ultrasonic Focusing Using Magnetic Resonance Guidance (2010)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation B. Larrat, M. Pernot, G. Montaldo, M. Fink, M. Tanter; Energy‐Based Adaptive Focusing: Optimal Ultrasonic Focusing Using Magnetic Resonance Guidance. AIP Conf. Proc. 9 March 2010; 1215 (1): 140–144. https://doi.org/10.1063/1.3367125 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
High-speed SOA Gate switch driver with equal-length wiring and peaking techniques (2008)

We developed a high-speed SOA gate-switch driver using an equal-length wiring technique. It can drive two SOAs simultaneously at 300 mA with a rising time of 2.5 ns for high-speed and high-port count optical switches.
Relationship between In Vitro Human Immunodeficiency Virus Type 1 Replication Rate and Virus Load in Plasma (2003)

Although plasma human immunodeficiency virus type 1 (HIV-1) RNA concentration is a major determinant of the rate of HIV-1 disease progression, the reasons for variability in plasma virus loads among infected individuals are not fully understood. We conducted investigations with 15 HIV-1-infected individuals who were not receiving antiretroviral therapy to evaluate the hypothesis that HIV-1 replication rate in vitro is a significant determinant of plasma virus load. Virus could not be isolated from one subject. Two subjects were excluded because they had features previously associated with distinct plasma virus loads and altered rates of disease progression; one harbored a syncytium-inducing virus and the second was heterozygous for a 32-bp deletion from the CCR5 gene. HIV-1 replication rates were determined by culturing autologous virus isolates in phytohemagglutinin-treated peripheral blood mononuclear cells (PBMC) and determining the rate of p24 antigen production during the logarithmic phase of viral replication. The contribution of HIV-1 reverse transcriptase (RT) and protease (PR) alleles to replication capacity was assessed using recombinant viruses in a single-cycle infection assay. HIV-1 replication rates ranged from 0.15 to 0.76 log(10) pg/ml/day and were reproducible within the same donor PBMC (coefficient of variation +/- 4%). RT-PR replication capacity ranged from 14 to 95% of that of control virus and was linearly related to replication rate (r(2) = 0.53; P = 0.007). Plasma HIV-1 RNA concentration was linearly related to replication rate (r(2) = 0.71; P < 0.001) and RT-PR replication capacity (r(2) = 0.44; P = 0.019). These data suggest that different RT-PR alleles are important determinants of HIV-1 replication rates and that HIV-1 replication rate explains much of the variability in plasma virus load in chronic HIV-1 infection.
A 32-Gb/s backplane transceiver with on-chip AC-coupling and low latency CDR in 32-nm SOI CMOS technology (2013)

This paper describes key design features of a 32-Gb/s 4-tap FFE/15-tap DFE transceiver in 32-nm SOI CMOS which mitigate major sources of degradation in transceiver performance. The transceiver employs a passive feed-forward restore (FFR) scheme in an on-chip AC-coupling network to prevent pattern-dependent baseline wander, a low latency clock and data recovery (CDR) to improve high frequency jitter tolerance, and a token-based power management scheme to reduce supply ripple. The transceiver can equalize a channel with 30dB of loss at a bit-error rate below 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−12</sup> while using 21 mW/Gbps at 1V supply and 0.7 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
A Scalable Video Rate Camera Interface (1994)

We survey the state of the art in high-speed interfaces for video input to high performance computers and note the difficulty of providing video at rates appropriate to modern parallel computers. Most interfaces that have been developed to date are not scalable, required extensive hardware development, and impose a full frame time delay between the moment the camera captures video and the moment it is available for processing. We propose a solution, based on a simple interface we have developed, which has been integrated into the iWarp parallel computer developed by Carnegie Mellon University and Intel Corporation. The interface takes advantage of iWarp's systolic capabilities, does not impose any frame buffer delay time, was simple to design, and is readily scalable to provide up to 32 camera ports, from all of which data can be captured at full video rate, on a system that fits in a 19' 6U rack. We have applied the system to multibaseline stereo vision, and provide performance figures. C.1.2 Multiple-instruction-stream, Multiple-data stream processors, Parallel processors, C.3 Real-time systems, 1.2.10 Vision and scene understanding, 1.2.9 Robotics, 1.3.1 Input devices, 1.4.1 Digitization, 1.4.2 Compression.
Advanced volume rendering algorithm for real-time 3D ultrasound: integrating pre-integration into shear-image-order algorithm (2006)

Volume rendering in 3D ultrasound is a challenging task due to the large amount of computation required for real-time rendering. The shear-warp algorithm has been traditionally used for 3D ultrasound rendering for its effectiveness in lowering computing cost. However, this lowered computing cost does come at the price of reduced image quality due to (a) the presence of final warp interpolation, which smoothes out fine details and (b) sampling only at discrete slice locations, which introduces aliasing, e.g., staircase artifacts. For 3D ultrasound, we have merged pre-integration with the shear-image-order algorithm to overcome both limitations of shear-warp while still enjoying the computational savings. Pre-integration overcomes the aliasing artifacts while shear-image-order preserves details. We have also developed a technique to integrate shading coefficient into pre-integrated rendering. This pre-integrated shear-image-order algorithm, with slightly higher computation than what is required to support the shear-warp algorithm, improves the quality of the rendered image significantly. In this paper, we discuss the pre-integrated shear-image-order algorithm and present the results of subjective quality evaluation on several data sets. We have also analyzed how this algorithm can be implemented on an advanced digital signal processor (DSP) to achieve real-time performance.