gebhart/patrepeval huggingface dataset:
New applications of inverse methods in the design of MRI coils (1998)

An inverse procedure is developed and applied to the design of new short actively shielded main magnet coils and new radio frequency (rf) coils in Magnetic Resonance Imaging (MRI). The new main magnet system is found through the use of inverse functional methods on bundled, discrete solenoidal coil systems, following the design procedure of Thompson et al. (1994). An additional wire bundle placed at the center of the system is a novel feature of the design. Similar functional methods are combined with the method of moments for the design of new rf coils where an advantage of the procedure is that it provides a computational technique for optimization of field uniformity, signal-to-noise, feeding, tuning, and impedance matching. Successful prototypes have been built for both of the new coil designs.
Patterns of angiogenesis in nonsmall-cell lung carcinoma (2001)

The authors believe that the alveolar vascular pattern represented preexisting alveolar vessels, that is, the alveoli were filled up by tumor cells that exploited the existing highly vascular bed of the lungs. Therefore, this subgroup was characterized by tumor progression without the induction of angiogenesis. The current data do not support a significant prognostic role for tumor angiogenesis in patients who are diagnosed with NSCLC. This may have implications for therapy aimed at inhibiting tumor growth by the inhibition of angiogenesis.
N-octanoyl-dopamine is a potent inhibitor of platelet function (2012)

Dopamine (DA) is a co-agonist for platelet activation; yet, donor DA treatment is associated with improved transplantation outcome in renal and heart recipients. Recently, N-octanoyl-dopamine (NOD) was developed which displays superior effects compared to DA in terms of graft protecting properties. Whereas DA is a known platelet co-agonist, the effect of NOD on platelet function is unknown. This is a hypothesis generating study with the aim to assess the effects and molecular mechanisms of NOD and NOD-like compounds on platelet function. The influence of DA, NOD, and NOD-like compounds on platelet responses to classical agonists (adenosine 5'-diphosphate (ADP), U46619) was investigated in six healthy donors by applying whole blood aggregometry (Multiplate®) and flow cytometry for Pac-1, CD62P, and CD63 expression. Changes in platelet cAMP concentrations were assessed by ELISA. While DA showed synergy in platelet activation by ADP and U46619, NOD caused significant inhibition of platelet function both in whole blood aggregometry and flow cytometry. The inhibitory effect of NOD was not mediated via cAMP levels. The nonredox-active NOD-analog N-octanoyl-tyramine had no effects on platelet function. Acetylated NOD conferred to NOD by intracellular esterases showed similar inhibitory effects as NOD. In contrast to DA, NOD is a potent inhibitor of platelet function most likely through intracellular redox-active processes. This adds to the overall protective effect of NOD on pre-transplantation injury and makes NOD an attractive candidate compound for donor or organ conditioning prior to transplantation.
IBX-Mediated Oxidation of Primary Alcohols and Aldehydes To Form Carboxylic Acids (2002)

Under mild conditions and without the use of toxic metals, the oxidation of primary alcohols and aldehydes to the corresponding carboxylic acids with 1-hydroxy-1,2-benziodoxole-3(1H)-one-1-oxide (IBX) proceeds in the presence of 1-hydroxypyridine or N-hydroxysuccinimide (see scheme). The reaction tolerates a wide variety of functional groups.
Tris(trimethylsilyl)silane (2022)

[1873-77-4] C9H28Si4 (MW 248.73) InChI = 1S/C9H28Si4/c1-11(2,3)10(12(4,5)6)13(7,8)9/h10H,1-9H3 InChIKey = SQMFULTZZQBFBM-UHFFFAOYSA-N (mediator of radical reactions1,2; nontoxic substitute for tri-n-butylstannane in radical reactions; slower hydrogen donor than tri-n-butylstannane3) Alternative names: TTMSS(TMS)3SiH. Physical Data: bp 82–84 °C/12 mmHg; d 0.806 g cm−3; n20D 1.489. Solubility: sol pentane, ether, toluene, THF; modestly sol acetone, acetonitrile; insol H2O; decomposes rapidly in methanol and other alcohols. Form Supplied in: colorless liquid; commercially available. Preparative Method: easy to synthesize.4 Handling, Storage, and Precautions: is slightly sensitive to oxygen and should be stored under nitrogen.5 It showed no toxicity in several biological test systems.6
ChemInform Abstract: An Efficient Large‐Scale Synthesis of Methyl 5‐[2‐(2,5‐Dimethoxyphenyl)ethyl]‐2‐hydroxybenzoate. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Ni Diffusion Studies from Fully-Silicided NiSi into Si (2006)

The interdiffusion of Ni from fully silicided NiSi metal gates through gate dielectrics into the Si substrate after annealing or forming gas annealing consistent with back-end-of-line thermal budgets is presented by using back-side secondary ion mass spectrometry profiling. Ni penetration is observed through thick SiON into the Si channel region after annealing for at temperatures of . However, Ni penetration through film into the Si channel is close to the limit of detection after annealing under similar conditions. The results suggest that Ni penetration can be suppressed by a dielectric film with sufficient thickness.
Effect of Methylprednisolone on the Pharmacokinetics of Lecithinized SOD(PC-SOD) in Mice. (1999)

The effect of methylprednisolone on the pharmacokinetics of lecithinized SOD (PC-SOD) was examined in mice. Methylprednisolone was simultaneously administered with [3H] PC-SOD, however there was no significant difference in the pharmacokinetics of [3H] PC-SOD. At 24 hr, the distribution of [3H] PC-SOD in some tissues was minimally changed. These results suggest that methylprednisolone has little influence on the biodistribution of PC-SOD, and co-administration of the two shows an additive pharmacological effect in clinical study.
Effect of Estriol and Bone Mineral Density of Lumbar Vertebrae in Elderly and Postmenopausal Women. (1996)

To compare the efficacy of estriol (E3) in postmenopausal and senile osteoporosis, we administered orally 1 g/day calcium lactate either alone (control groups) or with 2 mg/day estriol (estrogen groups) for 10 months to 20 postmenopausal women aged 50-65 years and to 29 elderly women aged 70-84 years, and measured their bone mineral density of the lumbar vertebrae by dual energy X-ray absorptiometry. Out of 41 subjects who completed 10 months of treatment, 8 postmenopausal women and 12 elderly women in the estrogen groups had significant (p < 0.05) increases in bone mineral density (5.59 +/- 4.79% of the respective basal values). Ten postmenopausal women and 11 elderly women in the control groups had decreases bone mineral density (-4.02 +/- 7.00% and -3.26 +/- 4.60% of the respective basal values) at the 10th month. Genital bleeding as a side effect of estriol was seen in 6 out 29 elderly subjects at this dose. Moreover, decreases in the levels of calcium, total cholesterol, and triglycerides in serum, and an increase in the level of high-density lipoprotein-cholesterol were seen only in the elderly women receiving estriol. Although a lower dosage of estriol may be recommended for elderly subjects, these observations suggest that hormone replacement therapy with estriol is effective against degenerative osteoporosis, and that low-turnover bones in elderly women are also responsive to estriol.
Oct-2, although not required for early B-cell development, is critical for later B-cell maturation and for postnatal survival. (1993)

Oct-2, a POU homeo domain transcription factor, is believed to stimulate B-cell-restricted expression of immunoglobulin genes through binding sites in immunoglobulin gene promoters and enhancers. To determine whether Oct-2 is required for B-cell development or function, or has other developmental roles, the gene was disrupted by homologous recombination. Oct-2-l- mice develop normally but die within hours of birth for undetermined reasons. Mutants contain normal numbers of B-cell precursors but are somewhat deficient in IgM+ B cells. These B cells have a marked defect in their capacity to secrete immunoglobulin upon mitogenic stimulation in vitro. Thus, Oct-2 is not required for the generation of immunoglobulin-bearing B cells but is crucial for their maturation to immunoglobulin-secreting cells and for another undetermined organismal function.
Performance evaluation for ML sequence detection in ISI channels with Gauss Markov Noise (2010)

Inter-symbol interference (ISI) channels with data dependent Gauss Markov noise have been used to model read channels in magnetic recording and other data storage systems. The Viterbi algorithm can be adapted for performing maximum likelihood sequence detection in such channels. However, the problem of finding an analytical upper bound on the bit error rate of the Viterbi detector in this case has not been fully investigated. Current techniques rely on an exhaustive enumeration of short error events and determine the BER using a union bound. In this work, we consider a subset of the class of ISI channels with data dependent Gauss-Markov noise. We derive an upper bound on the pairwise error probability (PEP) between the transmitted bit sequence and the decoded bit sequence that can be expressed as a product of functions depending on current and previous states in the (incorrect) decoded sequence and the (correct) transmitted sequence. In general, the PEP is asymmetric. The average BER over all possible bit sequences is then determined using a pairwise state diagram. Simulations results which corroborate the analysis of upper bound, demonstrate that analytic bound on BER is tight in high SNR regime. In the high SNR regime, our proposed upper bound obviates the need for computationally expensive simulation.
Ordered Attention for Coherent Visual Storytelling (2022)

We address the problem of visual storytelling, i.e., generating a story for a given sequence of images. While each story sentence should describe a corresponding image, a coherent story also needs to be consistent and relate to both future and past images. Current approaches encode images independently, disregarding relations between images. Our approach learns to encode images with different interactions based on the story position (i.e., past image or future image). To this end, we develop a novel message-passing-like algorithm for ordered image attention (OIA) that collects interactions across all the images in the sequence. Finally, to generate the story's sentences, a second attention mechanism picks the important image attention vectors with an Image-Sentence Attention (ISA). The obtained results improve the METEOR score on the VIST dataset by 1%. Furthermore, a thorough human study confirms improvements and demonstrates that order-based interactions significantly improve coherency (64.20% \vs 28.70%). Source code available at \urlhttps://github.com/tomateb/OIAVist.git
A novel elastomeric connector for packaging interconnections, testing and burn-in applications (2002)

Elasticon connectors have been developed for a wide variety of interconnection and test applications which include module-to-board, board-to-board interconnections; high density module, board and LCD testings; as well as chip/wafer testing and burn-in to produce Known-Good-Die. Depending on the applications, the Elasticon connectors can be fabricated into two basic types, the single-sided (integrated to a substrate) and the double-sided (interposer) structure. The single-sided structure, the Integrated Probe, is designed and fabricated for test and burn-in applications. The density, compliance, thickness, pattern and size of both the one- and two-sided structures can be easily tailored to meet the requirements of each specific application. The fabrication processes involve wire bonding, laser and polymer casting and curing. The electrical, mechanical and thermal properties of the connector have been fully characterized. To achieve high compliance with low contact force, a proprietary elastomeric material has been formulated to achieve not only high compliance but high thermal stability. The conductive element uses highly conductive, corrosion free, and oxidation resistant noble metals and their alloys. The reliability and durability of the elastomeric connector have been evaluated with mechanical cycling, thermal cycling, stress relaxation, outgassing, and temperature and humidity rest. The thermal stability of the connector, including both the polymer and the conductive element, has been measured to exceed the burn-in temperatures, which range from 125 to 180/spl deg/C.
Enhanced Surface Interactions Enable Fast Li+ Conduction in Oxide/Polymer Composite Electrolyte (2020)

Abstract Li + ‐conducting oxides are considered better ceramic fillers than Li + ‐insulating oxides for improving Li + conductivity in composite polymer electrolytes owing to their ability to conduct Li + through the ceramic oxide as well as across the oxide/polymer interface. Here we use two Li + ‐insulating oxides (fluorite Gd 0.1 Ce 0.9 O 1.95 and perovskite La 0.8 Sr 0.2 Ga 0.8 Mg 0.2 O 2.55 ) with a high concentration of oxygen vacancies to demonstrate two oxide/poly(ethylene oxide) (PEO)‐based polymer composite electrolytes, each with a Li + conductivity above 10 −4 S cm −1 at 30 °C. Li solid‐state NMR results show an increase in Li + ions (&gt;10 %) occupying the more mobile A2 environment in the composite electrolytes. This increase in A2‐site occupancy originates from the strong interaction between the O 2− of Li‐salt anion and the surface oxygen vacancies of each oxide and contributes to the more facile Li + transport. All‐solid‐state Li‐metal cells with these composite electrolytes demonstrate a small interfacial resistance with good cycling performance at 35 °C.
Complementary Algorithms For Tableaux (2000)

We study four operations defined on pairs of tableaux. Algorithms for the first three involve the familiar procedures of jeu de taquin, row insertion, and column insertion. The fourth operation, hopscotch, is new, although specialised versions have appeared previously. Like the other three operations, this new operation may be computed with a set of local rules in a growth diagram, and it preserves Knuth equivalence class. Each of these four operations gives rise to an a priori distinct theory of dual equivalence. We show that these four theories coincide. The four operations are linked via the involutive tableau operations of complementation and conjugation.
SERS Surfaces Modified with a 4-(2-Pyridylazo)resorcinol Disulfide Derivative: Detection of Copper, Lead, and Cadmium (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSERS Surfaces Modified with a 4-(2-Pyridylazo)resorcinol Disulfide Derivative: Detection of Copper, Lead, and CadmiumL. Gayle. Crane, DaoXin. Wang, L. Malia. Sears, Bernard. Heyns, and Keith. CarronCite this: Anal. Chem. 1995, 67, 2, 360–364Publication Date (Print):January 15, 1995Publication History Published online1 May 2002Published inissue 15 January 1995https://pubs.acs.org/doi/10.1021/ac00098a021https://doi.org/10.1021/ac00098a021research-articleACS PublicationsRequest reuse permissionsArticle Views760Altmetric-Citations87LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Supplemental Materials and Methods from A Systematic Comparison of <sup>18</sup>F-C-SNAT to Established Radiotracer Imaging Agents for the Detection of Tumor Response to Treatment (2023)

&lt;p&gt;Supplemental Materials and Methods. A detailed description of the radiosynthesis of each radiotracer, and detailed PET and SPECT imaging protocols.&lt;/p&gt;
Mass Deposition Measurements from 26-Kilowatt Electric Propulsion Space Experiment Flight (2002)

The Electric Propulsion Space Experiment (ESEX) was launched and operated in early 1999 to demonstrate the compatibility and readiness of a 30-kW class ammonia arcjet for satellite propulsion applications. As part of the onboard sensor array, thermoelectric quartz crystal microbalances were used to measure material deposition at selected locations on the spacecraft surface. The sensors were held at a temperature that would allow them to condense metallic materials eroded from the electrodes, but that are insensitive to possible deposition of the propellant gas. The ESEX arcjet was fired eight times, constituting 33 min and 26 s of operating time. No material deposition was observed that could be attributed to nominal the arcjet firings, although during the first firing, significant deposition was observed near the arcjet nozzle. This deposition is attributed to contaminants within the arcjet body, collected during handling and storage, which were ejected during the first firing. For future programs, although engineering measures may be needed to protect spacecraft equipment in the immediate vicinity of the thruster body, the arcjet environment causes negligible deposition of electrode material.
Rodent Tracking and Abnormal Behavior Classification in Live Video using Deep Neural Networks (2022)

This study is focused on developing tools to assess behavioral activity in neonatal mice undergoing opioid withdrawal. Opioids are used to manage pain in both young and old, but debilitating withdrawal symptoms can occur when opioid medications are stopped. We propose to apply various pre-trained neural network models such as ResNet, MobileNet, and EfficientNet to track mice behavior in live video using the DeepLabCut package. We track the animal by detecting movement and positioning of the “nose”, “right ear”, “left ear” and “tail base” in each video frame. Tracking is a prerequisite to detecting the abnormal behavior observed during precipitated withdrawal. We compare the performance of the different pretrained models in terms of accuracy. The highest accuracy that we achieved under abnormal conditions-opioid withdrawal using ResNet_50 was 95.82%.
Comparing the Bit-MAP and Block-MAP Decoding Thresholds of Reed-Muller\n Codes on BMS Channels (2016)

The question whether RM codes are capacity-achieving is a long-standing open\nproblem in coding theory that was recently answered in the affirmative for\ntransmission over erasure channels [1], [2]. Remarkably, the proof does not\nrely on specific properties of RM codes, apart from their symmetry. Indeed, the\nmain technical result consists in showing that any sequence of linear codes,\nwith doubly-transitive permutation groups, achieves capacity on the memoryless\nerasure channel under bit-MAP decoding. Thus, a natural question is what\nhappens under block-MAP decoding. In [1], [2], by exploiting further symmetries\nof the code, the bit-MAP threshold was shown to be sharp enough so that the\nblock erasure probability also converges to 0. However, this technique relies\nheavily on the fact that the transmission is over an erasure channel.\n We present an alternative approach to strengthen results regarding the\nbit-MAP threshold to block-MAP thresholds. This approach is based on a careful\nanalysis of the weight distribution of RM codes. In particular, the flavor of\nthe main result is the following: assume that the bit-MAP error probability\ndecays as $N^{-\\delta}$, for some $\\delta&gt;0$. Then, the block-MAP error\nprobability also converges to 0. This technique applies to transmission over\nany binary memoryless symmetric channel. Thus, it can be thought of as a first\nstep in extending the proof that RM codes are capacity-achieving to the general\ncase.\n
Effects of Interference on Wireless Mesh Networks: Pathologies and a Preliminary Solution. (2007)

Abstract – We highlight two fundamental problems that degrade the throughput of wireless mesh networks today. First, severe performance degradation can occur when sources send more traffic than what the network can support. The degradation can be sharp even in a simple setting of a single flow that traverses a network of two links. Second, current routing protocols fail to identify high throughput routing paths even when they exist. The underlying culprit in both cases is interference that is fundamental to wireless networks. As a first step towards a solution, we develop a novel approach to systematically account for and control interference in the network. Our approach uses (an approximation of) a formal model of interference to estimate the maximum rate at which flows can safely send traffic without overloading the network. Simulation and testbed experiments show that it can improve network throughput by as much as 50-100 % in some configurations. 1.
Supplementary Figure 6 from Personalized Chemotherapy Profiling Using Cancer Cell Lines from Selectable Mice (2023)

&lt;p&gt;PDF file - 77K, Chemosensitivity to topoisomerase inhibitors.&lt;/p&gt;
Unraveling the Anticancer Effect of Curcumin and Resveratrol (2016)

Resveratrol and curcumin are natural products with important therapeutic properties useful to treat several human diseases, including cancer. In the last years, the number of studies describing the effect of both polyphenols against cancer has increased; however, the mechanism of action in all of those cases is not completely comprehended. The unspecific effect and the ability to interfere in assays by both polyphenols make this challenge even more difficult. Herein, we analyzed the anticancer activity of resveratrol and curcumin reported in the literature in the last 11 years, in order to unravel the molecular mechanism of action of both compounds. Molecular targets and cellular pathways will be described. Furthermore, we also discussed the ability of these natural products act as chemopreventive and its use in association with other anticancer drugs.