gebhart/patrepeval huggingface dataset:
Refinement of the defect structure of `GeNb9O25' by high-resolution electron microscopy (1976)

It has been previously established that calculations of intensity distributions in high-resolution electron-microscope images of crystal structures can reproduce the experimental observations. The use of comparisons Of observed and computed images for structure analysis has been extended for the first time to the refinement of a defect structure in the case of crystals of nominal composition 'GeNb9O25. The results show that previously proposed models for the disordered atom configurations around 'tetrahedral' sites are not completely correct. A new model is proposed which shows good agreement between computed and observed images. This model suggests an interpretation for observations on other related structures in terms of a new type of defect.
ChemInform Abstract: A Bimetallic Zirconium Complex Containing an In‐Plane Bridging Aromatic Ring. (1989)

Abstract The bimetallic Zr complex (II) containing, in addition to an in‐plane bridging aromatic ring, a bridging methyl group is obtained according to the scheme.
Down‐regulation of glutatione S‐transferase α 4 (hGSTA4) in the muscle of thermally injured patients is indicative of susceptibility to bacterial infection (2011)

Patients with severe burns are highly susceptible to bacterial infection. While immunosuppression facilitates infection, the contribution of soft tissues to infection beyond providing a portal for bacterial entry remains unclear. We showed previously that glutathione S-transferase S1 (gstS1), an enzyme with conjugating activity against the lipid peroxidation byproduct 4-hydroxynonenal (4HNE), is important for resistance against wound infection in Drosophila muscle. The importance of the mammalian functional counterpart of GstS1 in the context of wounds and infection has not been investigated. Here we demonstrate that the presence of a burn wound dramatically affects expression of both human (hGSTA4) and mouse (mGsta4) 4HNE scavengers. hGSTA4 is down-regulated significantly within 1 wk of thermal burn injury in the muscle and fat tissues of patients from the large-scale collaborative Inflammation and the Host Response to Injury multicentered study. Similarly, mGsta4, the murine GST with the highest catalytic efficiency for 4HNE, is down-regulated to approximately half of normal levels in mouse muscle immediately postburn. Consequently, 4HNE protein adducts are increased 4- to 5-fold in mouse muscle postburn. Using an open wound infection model, we show that deletion of mGsta4 renders mice more susceptible to infection with the prevalent wound pathogen Pseudomonas aeruginosa, while muscle hGSTA4 expression negatively correlates with burn wound infection episodes per patient. Our data suggest that hGSTA4 down-regulation and the concomitant increase in 4HNE adducts in human muscle are indicative of susceptibility to infection in individuals with severely thermal injuries.
On Exact Computation with an Infinitely Wide Neural Net (2019)

How well does a classic deep net architecture like AlexNet or VGG19 classify on a standard dataset such as CIFAR-10 when its “width”— namely, number of channels in convolutional layers, and number of nodes in fully-connected internal layers — is allowed to increase to infinity? Such questions have come to the forefront in the quest to theoretically understand deep learning and its mysteries about optimization and generalization. They also connect deep learning to notions such as Gaussian processes and kernels. A recent paper [Jacot et al., 2018] introduced the Neural Tangent Kernel (NTK) which captures the behavior of fully-connected deep nets in the infinite width limit trained by gradient descent; this object was implicit in some other recent papers. An attraction of such ideas is that a pure kernel-based method is used to capture the power of a fully-trained deep net of infinite width. The current paper gives the first efficient exact algorithm for computing the extension of NTK to convolutional neural nets, which we call Convolutional NTK (CNTK), as well as an efficient GPU implementation of this algorithm. This results in a significant new benchmark for performance of a pure kernel-based method on CIFAR-10, being 10% higher than the methods reported in [Novak et al., 2019], and only 6% lower than the performance of the corresponding finite deep net architecture (once batch normalization etc. are turned off). Theoretically, we also give the first non-asymptotic proof showing that a fully-trained sufficiently wide net is indeed equivalent to the kernel regression predictor using NTK.
Orthopedic Coordinated Registry Network (Ortho-CRN): advanced infrastructure for real-world evidence generation (2022)

### Key messages Musculoskeletal conditions affect nearly three out of four persons aged 65 and older, one out of every two persons aged 18 and above and are responsible for up to one-third of pediatric medical problems.[1 2][1] The aging of the baby boomer generation, the increased demand for
Intradomain Overlays: Architecture and Applications (2003)

Abstract — We introduce an architecture for “Intradomain Overlays”, where a subset of routers within a domain is augmented with a dedicated host. These strategically placed hosts form an overlay network, and we describe a number of applications for such overlays. These applications include efficient network monitoring, policyand load-based packet re-routing, and network resource accounting. In this paper, we elaborate on the network monitoring application and describe a distributed protocol for monitoring routers within an AS which has been augmented with a few overlay nodes. The routers and other infrastructure are unaware of the overlay nodes, and the monitoring of individual elements is conducted using plain SNMP. We describe techniques for efficiently synthesizing and transporting the monitored SNMP data, and present results using trace data collected from an AS with 400+ routers. Our results show that the overlay-based monitoring reduces overheads by 2–4 orders of magnitude, and thus enables much finer grained monitoring and traffic engineering than is otherwise possible.
Simulation, design, and fabrication of thin-film resistive-gate GaAs charge coupled devices (2002)

Computer simulation of high-speed-gallium-arsenide charge coupled devices (CCDs) is performed using an established two-dimensional semiconductor device simulation program. The effect of active layer thickness on the charge transfer efficiency (CTE) and the dynamic range is investigated using different active layers. Also, different gate architectures are compared for optimum dynamic range and compatibility with GaAs MESFET technology. Both capacitive gate CCD and resistive gate CCD are considered. It is shown that both dynamic range and, to a greater extent, CTE, decrease with decreasing active layer thickness. In general, thicker active layer CCDs have a higher dynamic range and faster operating frequencies.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Six Year Review of All Subtrochanteric Fractures Treated at Hennepin County Medical Center (1993)

Ryder, Steven J.; Kyle, Richard F.; Campbell, Sara J.; Templeman, David C.; Orafkovich, M. Author Information
CD14+ Monocytes Are Vulnerable and Functionally Impaired Under Endoplasmic Reticulum Stress in Patients With Type 2 Diabetes (2009)

These data suggest that monocytes comprise a substantially impaired subpopulation of PBMCs in patients with diabetes and that ER stress is involved in these pathologic changes mechanistically. This implies that the affected monocytes should be investigated further to better understand diabetic immunity.
A 200mW D-band Power Amplifier with 17.8% PAE in 250-nm InP HBT Technology (2021)

We report a compact and high efficiency D-band power amplifier in 250nm InP HBT technology. A compact and low loss 8:1 transmission line power combiner is demonstrated. The three-stage power amplifier combines 8 capacitively linearized common-base power cells. The amplifier has 23dBm peak power with 17.8% power added efficiency (PAE) and 16.5dB associated large-signal gain at 131GHz. At 131GHz, the small-signal gain is 21.9dB. The small-signal 3dB-bandwidth is 125.8-145.8GHz. Over the 127-151GHz bandwidth, the saturated output power is greater than 22.3dBm with greater than 15% associated PAE. The amplifier occupies 1.34mm2 die area and consumes 1.1W DC power. To the authors' knowledge, this result demonstrates a record PAE.
Fast relapse and high drop out rate of 48 weeks daily interferon monotherapy in HIV-infected patients with chronic hepatitis C (2002)

Although our results demonstrated a very poor outcome and a bad tolerance to interferon monotherapy, this approach should not be dropped out, mainly in patients at high risk for side effects and in those with cirrhosis who do not tolerate or are at increased risk for the use of ribavirin.
Reclamation of Oily Wastewater at High Temperatures Using Thermosetting Polyurethane-Nanosilicon Sponges (2021)

Reclamation of fracking wastewater at its high discharge temperature is a global energy and environmental challenge. Herein, the utilization of thermosetting polyurethane-nanosilicon sponges with thermal stability up to 220 °C is demonstrated for reclaiming emulsified oily wastewater between 30 and 100 °C. The sponge achieved 92–96% removal efficiency within 5 min where efficiency of 27% was increased by melting wax crystallites in the crude oil. The adsorbed oil was extracted from the sponge by rinsing with Heptol. These results show that thermoset polymers are promising high-temperature sorbents to reclaim fracking effluents and achieve Net-Zero goals in the oil industry.
Software and Hardware Design Issues for Low Complexity High Performance Processor Architecture (2009)

Queue processor offers an attractive option in the design of general purpose and applications specific systems. This paper presents software and hardware design issues for extracting high instruction level parallelism for the 32-bit queuecore processor. We propose code generation algorithm for the queuecore architecture. Compiling for the queuecore requires a new approach since the concept of registers disappears. The compiler extracts more parallelism than the optimizing compiler for a RISC machine over a set of various numerical benchmark programs. In addition, we are able to generate in average about 23% denser code than two embedded RISC processors.
O-Band GeSi Quantum-Confined Stark Effect Electro-Absorption Modulator Integrated in a 220nm Silicon Photonics Platform (2020)

We report on a waveguide-coupled quantum-confined Stark effect (QCSE) electro-absorption modulator integrated in a 220nm Si photonics platform and operating in 1335-1365nm wavelength range. The device is based on a strain-balanced GeSi quantum well/barrier stack grown on an ultra-thin strain-relaxed buffer. The stack is only 450nm thick, facilitating optical coupling to sub-micron Si waveguides. An extinction ratio up to 8dB is achieved in a 40μm long device for a 1 Vpp drive voltage, demonstrating the potential of this modulator for low-power optical interconnect applications.
PAK1 mediates pancreatic cancer cell migration and resistance to MET inhibition (2014)

Pancreatic adenocarcinoma (PDAC) is a major unmet medical need and a deeper understanding of molecular drivers is needed to advance therapeutic options for patients. We report here that p21-activated kinase 1 (PAK1) is a central node in PDAC cells downstream of multiple growth factor signalling pathways, including hepatocyte growth factor (HGF) and MET receptor tyrosine kinase. PAK1 inhibition blocks signalling to cytoskeletal effectors and tumour cell motility driven by HGF/MET. MET antagonists, such as onartuzumab and crizotinib, are currently in clinical development. Given that even highly effective therapies have resistance mechanisms, we show that combination with PAK1 inhibition overcomes potential resistance mechanisms mediated either by activation of parallel growth factor pathways or by direct amplification of PAK1. Inhibition of PAK1 attenuated in vivo tumour growth and metastasis in a model of pancreatic adenocarcinoma. In human tissues, PAK1 is highly expressed in a proportion of PDACs (33% IHC score 2 or 3; n = 304) and its expression is significantly associated with MET positivity (p < 0.0001) and linked to a widespread metastatic pattern in patients (p = 0.067). Taken together, our results provide evidence for a functional role of MET/PAK1 signalling in pancreatic adenocarcinoma and support further characterization of therapeutic inhibitors in this indication.
Steady-state analysis of second-order traffic models and application to traffic flow control (2019)

We investigate the problem of controller design after linearization around the steady-state solutions of second-order traffic models. At steady-state the traffic variables follow space-dependent autonomous ODEs. The steady-state solutions can be used to account for the heterogeneity of the road in space, which can be caused by different environmental factors. Proceeding by analogy with open-channel flow studies, where such states are relevant for operating a network with efficient control strategies, we analyse and compare steady-state solutions for different second-order traffic models. We show that the steady-state density profile remains in three different regions. The behaviour of the considered models is discussed, leading to proposed corrections of the models. We select one corrected model, which we use for the design and implementation of a boundary controller to illustrate the effectiveness of our approach.
Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4 (2000)

To determine whether IL-4 is therapeutic in treating established experimental arthritis, a recombinant adenovirus carrying the gene that encodes murine IL-4 (Ad-mIL-4) was used for periarticular injection into the ankle joints into mice with established collagen-induced arthritis (CIA). Periarticular injection of Ad-mIL-4 resulted in a reduction in the severity of arthritis and joint swelling compared with saline- and adenoviral control groups. Local expression of IL-4 also reduced macroscopic signs of joint inflammation and bone erosion. Moreover, injection of Ad-mIL-4 into the hind ankle joints resulted in a decrease in disease severity in the untreated front paws. Systemic delivery of murine IL-4 by intravenous injection of Ad-mIL-4 resulted in a significant reduction in the severity of early-stage arthritis.
Hybrid Analog-Digital Transceiver Designs for Multi-User MIMO mmWave Cognitive Radio Systems (2019)

Millimeter wave (mmWave) band mobile communications can be a solution to the continuously increasing traffic demand in modern wireless systems. Even though mmWave bands are scarcely occupied, the design of a prospect transceiver should guarantee the efficient coexistence with the incumbent services in these bands. To that end, in this paper, multi-user underlay cognitive transceiver designs are proposed that enable the mmWave spectrum access while controlling the interference to the incumbent users. MmWave systems usually require large-scale antenna arrays to achieve satisfactory performance and thus, it is difficult to support fully digital transceiver designs due to high demands in hardware complexity and power consumption. Thus, in order to develop efficient solutions, the proposed approaches are based on a hybrid analog-digital (A/D) architecture. Transceiver designs are developed for both the uplink and the downlink regime of a multi-user cellular system. Efficient algorithmic solutions are proposed for the design of the analog and the digital counterparts of the precoding and the decoding matrices of the latter systems based on the Alternating Direction Method of Multipliers (ADMM). Simulations show that the performance of the proposed hybrid A/D approaches is very close to the one of the corresponding fully digital transceivers for typical experimental setups.
Whole-genome epidemiology, characterisation, and phylogenetic reconstruction of Staphylococcus aureus strains in a paediatric hospital (2018)

Whole genome sequencing allowed us to study the epidemiology and genomic repertoire of S. aureus in a clinical setting and provided evidence of its often underestimated complexity. Some virulence factors and clones are specific of disease types, but the variability and dispensability of many antigens considered for vaccine development together with the quickly changing epidemiology of S. aureus makes it very challenging to develop full-coverage therapies and vaccines. Expanding WGS-based surveillance of S. aureus to many more hospitals would allow the identification of specific strains representing the main burden of infection and therefore reassessing the efforts for the discovery of new treatments and clinical practices.
Research Guides: Wagner College Archive: Ask a Librarian (2012)

The Wagner Archive is dedicated to collecting and preserving materials documenting the history and legacy of Wagner College.
Aryldiones incorporating a [1,4,5]oxadiazepane ring. Part 2: Chemistry and biology of the cereal herbicide pinoxaden (2011)

The biological potential of pinoxaden and its active principle pinoxaden dione in terms of grass weed control and tolerance in cereals was fully exploited by inclusion of the safener cloquintocet-mexyl in the formulation in combination with a specific and tailor-made tank-mix adjuvant based on methylated rape seed oil.
Seamless MPLS Architecture (2014)

This documents describes an architecture which can be used to extend
MPLS networks to integrate access and aggregation networks into a
single MPLS domain (Seamless MPLS). The Seamless MPLS approach is
based on existing and well known protocols. It provides a highly
flexible and a scalable architecture and the possibility to integrate
100.000 of nodes. The separation of the service and transport plane is
one of the key elements; Seamless MPLS provides end to end service
independent transport. Therefore it removes the need for service
specific configurations in network transport nodes (without end to end
transport MPLS, some additional services nodes/configurations would be
required to glue each transport domain). This draft defines a routing
architecture using existing standardized protocols. It does not invent
any new protocols or defines extensions to existing protocols.
In Situ Neutron Powder Diffraction of the Formation of SrGa2D2, and Hydrogenation Behavior of YbGa2 and EuGa2 (2013)

The hydrogenation behavior of the Zintl phases MGa2 (M = Sr, Eu, Yb) was investigated. Upon being heated under 50 bar of hydrogen gas pressure, SrGa2 starts forming the polyanionic hydride SrGa2H2 at 125 °C as observed by in situ differential scanning calorimetry (DSC) and ex situ X-ray powder diffraction. The deuteration of SrGa2 was studied by in situ neutron powder diffraction at temperatures up to 300 °C in the pressure range of 50 ≤ p(D2) ≤ 61 bar with a time resolution of two minutes. Neither incorporation of deuterium into the interstitials of the crystal structure of SrGa2 nor any other intermediate of the reaction was observed. No significant variation in positional or occupational parameters as refined by the Rietveld method was observed for the deuteride SrGa2D2 under various temperature and pressure conditions (e.g., at T = 299 °C, p(D2) = 60 bar, space group P3m1, a = 4.4098(2) Å, c = 4.7429(3) Å, Sr in 1a, 0 0 0; Ga in 2d, 1/3 2/3 0.474(1); D in 2d, 1/3 2/3 0.120(2)). In situ DSC complemented by ex situ X-ray powder diffraction revealed that EuGa2 and YbGa2 do not form polyanionic hydrides in the investigated temperature-pressure ranges (20 °C ≤ T ≤ 220 °C, 5 bar ≤ p ≤ 54 bar). Instead binary hydrides and gallium-rich intermetallics are formed. The first refined crystal structural data are presented for YbGa6 in the tetragonal PuGa6-type structure (space group P4/nbm (No. 125), a = 6.0890(3) Å, c = 7.6562(4) Å, Yb in 2c, 3/4 1/4 0; Ga1 in 8m, 0.4750(4) 0.5250(4) 0.3377(4); Ga2 in 4g, 1/4 1/4 0.1691(5)).
Semi-Global 3D Line Modeling for Incremental Structure-from-Motion (2014)

Recovering 3D information from a single moving camera is a widely studied field in the area of computer vision (e.g. [1]). Most of these Structurefrom-Motion (SfM) approaches are based on so-called interest points (e.g. corners) in images, which can be accurately matched using powerful descriptors like SIFT [7]. Hence the output is usually a sparse 3D point cloud along with the camera poses for all successfully integrated images. While previous methods were only able to perform pose estimation and 3D reconstruction in an offline way, there are now more and more incremental SfM approaches available (e.g. [4]). Since conventional SfM approaches are based on interest points, the distribution of the obtained 3D points is usually not uniform throughout the whole reconstruction. This is due to the fact that such interest points are usually located on highly textured areas, but not on homogeneous regions or along edges. Since the result of SfM pipelines is often used as basis to generate a more dense result or for localization and navigation tasks, it would be beneficial to generate additional complementary 3D information in an efficient way. From a SfM point of view, using line segments is especially interesting for urban and indoor environments, where linear structures frequently occur. While interest points are located mostly on richly textured image locations, line segments usually mark the boundaries of objects. Hence, incorporating such features in an online SfM pipeline to create 3D line segments naturally leads to a more complete 3D representation of the underlying scene, which is beneficial for all kinds of subsequent applications. We propose a novel approach which generates 3D line models in a semi-global way directly on-the-fly, based solely on the output of a conventional incremental SfM pipeline. The goal of our method is to generate additional complementary 3D information to improve the sparse 3D representation of the scene. In this approach, we consider the SfM pipeline as a black box and do not interfere with the pose estimation procedure. We show that 3D line reconstructions can be obtained very efficiently by using purely geometric constraints, or by additionally incorporating appearance and collinearity information. Our approach enables accurate 3D reconstruction of texture-less as well as textured man-made objects, including complex structures such as wiry objects. Figure 1 shows a reconstruction result obtained by an incremental SfM system [4], followed by a surface generation method [5], with and without the usage of additional 3D line segments obtained by our proposed method. As we can see, additional 3D information significantly improves the completeness and overall appearance of the resulting reconstructions. For more technical details, we kindly refer to the full paper.
Identifica\c{c}\~ao autom\'atica de picha\c{c}\~ao a partir de imagens urbanas. (2018)

Graffiti tagging is a common issue in great cities an local authorities are on the move to combat it. The tagging map of a city can be a useful tool as it may help to clean-up highly saturated regions and discourage future acts in the neighbourhood and currently there is no way of getting a tagging map of a region in an automatic fashion and manual inspection or crowd participation are required. In this work, we describe a work in progress in creating an automatic way to get a tagging map of a city or region. It is based on the use of street view images and on the detection of graffiti tags in the images.