gebhart/patrepeval huggingface dataset:
Predictive In-Cycle Closed-Loop Combustion Control with Pilot-Main Injections (2020)

This paper studies the use of predictive in-cycle close-loop combustion control to reduce the stochastic cyclic variations of diesel combustion. The combustion metrics that fully define the pressure trace with a pilot-main injection i.e. pilot and main start of combustion, burned pilot mass, and engine load are used as the set-point reference. These metrics are in-cycle predicted by calibrated models as functions of the current cylinder state, estimated by in-cylinder pressure measurements. The proposed approach uses four individual controllers for the set-point error minimization, which respectively regulate the injection’s timing and duration of the pilot-main injection. The controllers are implemented in a FPGA and tested in a Scania D13 engine. The steady-state error reduction, disturbance rejection and transient response are discussed. The results confirm the error reduction in both, cycle-to-cycle and cylinder-to-cylinder variations. The error dispersion, measured by the 95% confidence interval, was reduced between 25% and 75% for all the controlled parameters. By on-line adaptation, the controllers are robust against model uncertainties and fuel types.
Weyl points and line nodes in gapless gyroid photonic crystals (2012)

Weyl points and line nodes are three-dimensional linear point- and line-degeneracies between two bands. In contrast to Dirac points, which are their two-dimensional analogues, Weyl points are stable in the momentum space and the associated surface states are predicted to be topologically non-trivial. However, Weyl points are yet to be discovered in nature. Here, we report photonic crystals, based on the double-gyroid structures, exhibiting frequency-isolated Weyl points with intricate phase diagrams. The surface states associated with the non-zero Chern numbers are demonstrated. Line nodes are also found in similar geometries; the associated surface states are shown to be flat bands. Our results are readily experimentally realizable at both microwave and optical frequencies.
Pseudomonas exotoxin: recombinant conjugates as therapeutic agents (1992)

Conference Article| November 01 1992 Pseudomonas exotoxin: recombinant conjugates as therapeutic agents David J. FitzGerald; David J. FitzGerald 1Laboratory of Molecular Biology, Department of Health and Human Services, National Cancer Institute, Bethesda, Maryland 20892, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar Ira Pastan Ira Pastan 1Laboratory of Molecular Biology, Department of Health and Human Services, National Cancer Institute, Bethesda, Maryland 20892, U.S.A. Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1992) 20 (4): 731–734. https://doi.org/10.1042/bst0200731 Article history Received: July 23 1992 Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation David J. FitzGerald, Ira Pastan; Pseudomonas exotoxin: recombinant conjugates as therapeutic agents. Biochem Soc Trans 1 November 1992; 20 (4): 731–734. doi: https://doi.org/10.1042/bst0200731 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search Keywords: PE, Pseudomonas exotoxin, EF-2, elongation factor-2, Ab, antibody This content is only available as a PDF. © 1992 Biochemical Society1992 Article PDF first page preview Close Modal You do not currently have access to this content.
A layered approach to robust lane detection at night (2009)

A layered approach is designed to address many of the real-world problems that an inexpensive lane detection system would encounter. A region of interest is first extracted from the image followed by an enhancement procedure to manipulate the shape of the lane markers. The extracted region is then converted to binary using an adaptive threshold. A model based line detection system hypothesizes lane position. Finally, an iterated matched filtering scheme estimates the final lane position. The developed system shows good performance when tested on real-world data that contains fluctuating illumination and a variety of traffic conditions.
Enzymatic Baeyer–Villiger oxidations of some bicyclo[2.2.1]heptan-2-ones using monooxygenases from Pseudomonas putida NCIMB 10007: enantioselective preparation of a precursor of azadirachtin (1995)

Two monooxygenases MO1 (NADH dependent) and MO2 (NADPH dependent) isolated from Ps. putida NCIMB 10007 [grown on (+)-camphor] have been utilized as biocatalysts in Baeyer–Villiger oxidations. The former enzyme oxidized the racemic ketones 9, 10 and 14 into the optically active lactones 15–17. The ketone 9 is not oxidized by MO2 but the ketones 10 and 14 gave the optically active lactones 16 and 17. Whole-cell preparations of Ps. putida degraded the ketone 9 but transformed the racemic ketones 10 and 14 into the optically active lactones 16 and 17. All the lactones possess the same absolute configuration: 1S, 5S, 6R. (+)-MO1 [the isozyme which metabolizes (+)-camphor], oxidized the ketone 10 but not the ketone 9. Conversely, (–)-MO1 [the isozyme which metabolizes (–)-camphor], catalysed the oxidation of the ketone 9 but not the ketone 10. Co-factor recycling was effected using dehydrogenase enzymes in preparative-scale experiments. The optically active lactone 17 is an intermediate in the synthesis of compound 5, an important precursor of azadirachtin 6.
Expression of H-2 class I genes in murine extra-embryonic tissues. (1988)

Murine major histocompatibility complex class I genes are transcribed at high levels in placental tissues, lower levels in yolk-sac tissues and at barely detectable levels in the embryo at Day 13.5 of gestation. Genes are expressed at equivalent levels whether inherited maternally or paternally, and the genetic background has no effect on class I gene transcription. These results show that potential alloantigens are expressed in extra-embryonic tissues intimately associated with maternal tissues and blood supply and yet fail to induce immunological rejection.
Visualization of Self-Organizing Networks Operated by the ANR Algorithm (2009)

Cellular radio networks are continually growing in both node count and complexity. It therefore becomes more and more difficult to manage the networks and necessary to use time and cost effective automatic computer algorithms to organize the network's neighbor cell relations. Ericsson has developed such an algorithm, called automatic neighbor relations (ANR), which solves a part of this problem by automatically creating and updating neighbor cell relation (NCR) lists, based on measured network data. Network operators need to have an understanding of the algorithm and of its reliability and performance, which is not easily perceived. This paper presents a visualization tool that visualizes the performance of ANR and gives the user a possibility to control it via policies. The tool allows the operators to follow the evolution of the network and to find problems occurring over time. In addition, it also supports finding potential problems that can occur in the future. The tool was evaluated by a group of relevant domain users and the results from the evaluation were highly positive.
Data from A Novel Human Her-2/neu Chimeric Molecule Expressed by <i>Listeria monocytogenes</i> Can Elicit Potent HLA-A2 Restricted CD8-positive T cell Responses and Impact the Growth and Spread of Her-2/neu-positive Breast Tumors (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; The aim of this study was to efficiently design a novel vaccine for human Her-2/neu-positive (hHer-2/neu) breast cancer using the live, attenuated bacterial vector &lt;i&gt;Listeria monocytogenes&lt;/i&gt;.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; Three recombinant &lt;i&gt;L. monocytogenes&lt;/i&gt;–based vaccines were generated that could express and secrete extracellular and intracellular fragments of the hHer-2/neu protein. In addition, we generated a fourth construct fusing selected portions of each individual fragment that contained most of the human leukocyte antigen (HLA) epitopes as a combination vaccine (&lt;i&gt;L. monocytogenes&lt;/i&gt;–hHer-2/neu chimera).&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; Each individual vaccine was able to either fully regress or slow tumor growth in a mouse model for Her-2/neu-positive tumors. All three vaccines could elicit immune responses directed toward human leukocyte antigen-A2 epitopes of hHer-2/neu. The &lt;i&gt;L. monocytogenes&lt;/i&gt;–hHer-2/neu chimera was able to mimic responses generated by the three separate vaccines and prevent spontaneous outgrowth of tumors in an autochthonous model for Her-2/neu-positive breast cancer, induce tumor regression in transplantable models, and prevent seeding of experimental lung metastases in a murine model for metastatic breast cancer.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusion:&lt;/b&gt; This novel &lt;i&gt;L. monocytogenes&lt;/i&gt;–hHer-2/neu chimera vaccine proves to be just as effective as the individual vaccines but combines the strength of all three in a single vaccination. These encouraging results support future clinical trials using this chimera vaccine and may be applicable to other cancer types expressing the Her-2/neu molecule such as colorectal and pancreatic cancer.&lt;/p&gt;&lt;/div&gt;
Author Correction: Fermiology and electron dynamics of trilayer nickelate La4Ni3O10 (2018)

The original version of this Article contained errors in Fig. 2, Fig. 3a-c and Supplementary Fig. 2. In Fig. 2g and Supplementary Fig. 2, the band structure plot calculated from density function theory (DFT) had a missing band of mainly z<sup>2</sup> character that starts at about - 0.25 eV at the Y point and disperses downwards towards the Γ point. This band was inadvertently neglected when transferring the lines from the original band plot to the enhanced version for publication. Also in Fig. 2g, the points labelled M and Y were not exactly at (1/2 1/2 0) and (0 1/2 0), but rather (0.52 0.48 0) and (0 0.48 0) due to a bug in XCrysDen for low-symmetry structures that the authors failed to identify before publication. Thus, the bands presented were slightly off the true M-Y direction and additional splitting incorrectly appeared (in particular for the highly dispersive bands of x<sup>2</sup>-y<sup>2</sup> character). The correct versions of Fig. 2g (cited as Fig. 1) and Supplementary Fig. 2 (cited as Fig. 2) are:which replaces the previous incorrect version, cited here as Fig. 3 and Fig. 4:Neither of these errors in Fig. 2g or Supplementary Fig. 2 affects either the discussion or any of the interpretations of the ARPES data provided in the paper. The authors discussed the multilayer band splitting along the Γ-M direction (δ band and α band as assigned in the paper), and ARPES did not see any split band. The authors did not discuss the further splitting that arises due to back folding along the M-Y direction.In Fig. 3a-c, the errors in the M and Y points in Fig. 2g cause subtle changes to the DFT dispersions. The correct version of Fig. 3a-c is cited here as Fig 5:which replaces the previous incorrect version (Fig. 6):However, the influence on the effective mass results of Fig. 3d is negligible.These errors have now been corrected in both the PDF and HTML versions of the Article. The authors acknowledge James Rondinelli and Danilo Puggioni from Northwestern University for calling our attention to these issues.
Ambient air, by near-ambient pressure XPS (2019)

Near-ambient pressure x-ray photoelectron spectroscopy (NAP-XPS) is a less traditional form of XPS that allows samples to be analyzed at relatively high pressures, i.e., at 2500 Pa or higher. With NAP-XPS, XPS can analyze moderately volatile liquids, biological samples, porous materials, and/or polymeric materials that outgas significantly. Because of the relatively high working pressure of NAP-XPS, the components of ambient air may be present in the analytical chamber during data acquisition. In this submission, we show survey, O 1s, N 1s, valence band, oxygen Auger (KLL), and nitrogen Auger (KLL) NAP-XPS spectra from ambient air, a material that could not be analyzed at moderate pressures by conventional XPS.
Fast multiplicity counter featuring stilbene detectors for special nuclear material assay (2015)

A fast neutron multiplicity counting system based on organic scintillators, i.e. EJ-309 and stilbene, has been developed and experimentally tested at the University of Michigan. The system is able to detect correlated photon and neutron multiplets emitted by the fission reaction, within a gate time of tens of nanoseconds. This counting strategy is exploited to quantify fissile mass, without the need of complex electronic circuitry and unfolding procedures, otherwise required in moderated systems. Moderated systems are traditionally based on helium-3 detectors and feature a gate time of hundreds of microseconds. Measurement precision is thus negatively affected by accidental coincidences. A prototypal version of the proposed well-shaped counter was assembled and tested in the laboratory, using a spontaneous fission and an (α, n) neutron source, i.e. <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">252</sup> Cf and PuBe respectively. Measured results show excellent agreement with the simulated model of the system. The viability of the system to discriminate time-correlated fission neutrons from random, uncorrelated neutrons was proved. Preliminary results of an experimental campaign, carried out at INL (Idaho National Laboratory), to characterize plutonium metal samples are also shown. Results show a monotonic increasing trend for the range of measured 240-Pu effective masses, i.e. 0.024-0.5 kg, enabling the measurement of the mass of an unknown sample.
Phosphorus Components in Lubricants: Structure-Activity Relationship (2002)

Phosphorus components are probably the earliest known and most important additives for lubricant applications. Phosphites, phosphates, thiophosphates, metal dithiophosphates, and amine phosphates are examples of common phosphorus additives being used in the lubricant industry. However, due to environmental concerns and to help conserve catalyst life of catalytic converters, there is a trend to reduce the phosphorus content in lubricant formulations. In order to achieve this goal, different types of phosphorus components have been studied for their tribological properties.
Using computational fluid dynamics to evaluate a novel venous cannula (Smart canula ®) for use in cardiopulmonary bypass operating procedures (2007)

Peripheral access cardiopulmonary bypass (CPB) is initiated with percutaneous cannulae (CTRL) and venous drainage is often impeded due to smaller vessel and cannula size. A new cannula (Smartcanula, SC) was developed which can change shape in situ and, therefore, may improve venous drainage. Its performance was evaluated using a 2-D computational fluid dynamics (CFD) model. The Navier-Stokes equations could be simplified due to the fact that we use a steady state and a 2-dimensional system while the equation of continuity (p constant) was also simplified. We compared the results of the SC to the CTRL using CFDRC (Version 6.6, CFDRC research corporation, Huntsville, USA) at two preloads (300 and 700 Pa). The SC's mass flow rate outperformed the CTRL by 12.1% and 12.2% at a pressures of 300 and 700 Pa, respectively. At 700 Pa, a pressure gradient of 50% was measured for the CTRL and 11% for the SC. The mean velocity at the 700 Pa for the CTRL was 1.0 m.s(-1) at exit while the SC showed an exit velocity of 1.3 m.s(-1). Shear rates inside the cannulae were similar between the two cannulae. In conclusion, the prototype shows greater mass flow rates compared to the classic cannula; thus, it is more efficient. This is also advocated by a better pressure gradient and higher average velocities. By reducing cannula-tip surface area or increasing hole surface area, greater flow rates are achieved.
Measurement of inclusive and differential cross sections in the H → ZZ * → 4ℓ decay channel in pp collisions at s=13$$ \sqrt{s}=13 $$ TeV with the ATLAS detector (2017)

Inclusive and differential fiducial cross sections of Higgs boson production in proton-proton collisions are measured in the H ZZ * 4 decay channel. The protonproton collision data were produced at the Large Hadron Collider at a centre-of-mass energy of 13 TeV and recorded by the ATLAS detector in 2015 and 2016, corresponding to an integrated luminosity of 36.1 fb -1 . The inclusive fiducial cross section in the H ZZ * 4 decay channel is measured to be 3.62 0.50 (stat) +0.25 -0.20 (sys) fb, in agreement with the Standard Model prediction of 2.91 0.13 fb. The cross section is also extrapolated to the total phase space including all Standard Model Higgs boson decays. Several differential fiducial cross sections are measured for observables sensitive to the Higgs boson production and decay, including kinematic distributions of jets produced in association with the Higgs boson. Good agreement is found between data and Standard Model predictions. The results are used to put constraints on anomalous Higgs boson interactions with Standard Model particles, using the pseudo-observable extension to the kappa-framework.
Identification and analysis of transcriptional regulatory signals for the kil and kor loci of Streptomyces plasmid pIJ101 (1989)

Four regulated promoters that direct the transcription of genes (i.e., korA, tra, kilB, and korB) involved in the transfer of the Streptomyces plasmid pIJ101 were isolated following the in vitro fusion of plasmid DNA fragments to a promoterless gene encoding the S. lividans extracellular enzyme beta-galactosidase. Introduction of pIJ101 into cells carrying each of these promoter-lac fusions resulted in decreased lac expression. The sites of initiation of transcription by the promoter sequences were identified by primer extension experiments, and the DNA sequences specifically required for promoter activity and regulation by pIJ101-encoded functions were determined by deletion analysis. The data obtained indicate that the korB locus encodes a repressor that regulates its own transcription, as well as transcription of the kilB promoter; korA and tra are transcribed from overlapping divergent promoters that are coregulated by the korA gene product. Common DNA sequence domains within coregulated promoters allowed the identification of putative binding sites for each of the kor gene products.
Crystallization Kinetics of Organic–Inorganic Trihalide Perovskites and the Role of the Lead Anion in Crystal Growth (2015)

Methylammonium lead halide perovskite solar cells continue to excite the research community due to their rapidly increasing performance which, in large part, is due to improvements in film morphology. The next step in this progression is control of the crystal morphology which requires a better fundamental understanding of the crystal growth. In this study we use in situ X-ray scattering data to study isothermal transformations of perovskite films derived from chloride, iodide, nitrate, and acetate lead salts. Using established models we determine the activation energy for crystallization and find that it changes as a function of the lead salt. Further analysis enabled determination of the precursor composition and showed that the primary step in perovskite formation is removal of excess organic salt from the precursor. This understanding suggests that careful choice of the lead salt will aid in controlling crystal growth, leading to superior films and better performing solar cells.
Determination of atom locations on surfaces with x-ray standing waves (2020)

Standing waves of x-rays have been utilized to locate adsorbed atom positions on crystal surfaces. In addition to positions normal to the surface the component relative to a plane inclined to the surface has been determined. This suffices to establish the registration of the adsorbed surface atoms to the crystal lattice below.
<title>Comparison of case retrieval times: film versus PACS</title> (1992)

One of the advantages which a picture archiving and communications system (PACS) is supposed to provide over film-based operation is improved performance in retrieving images. While is seems self-evident that this should be so, we wanted to verify this, and provide some time comparisons for the two methods. The experiment consisted of randomly selecting ultrasound (US) and computed tomography (CT) cases and determining how long it took to retrieve them at one of our PACS workstations, and to retrieve them in person from the film room. To simulate actual retrieval volumes, a total of 40 cases from current to six months old, 20 cases from the past year, and 10 cases over one year old, was selected. Results indicate that indeed, PACS retrieval can be faster than file room retrieval. However, the difference is less for recent cases than for older cases. For cases six or fewer months old, the workstation retrieval was about two and one-half minutes faster per case than the film file room. This time difference increased markedly when extended to the one year and over one year groups. This paper details the results of this study, and will also provide information about the reliability of the two archives.
Formulation ALE et remaillage adaptatif : application à la modélisation du fluotournage (2007)

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Epidermal growth factor receptor localized to exosome membranes as a possible biomarker for lung cancer diagnosis. (2013)

Detection of drug-target proteins and biomarkers that are expressed in cancer tissue has significant potential for both diagnosis and treatment of cancer. However, current immuno-histochemical and cytogenetic analyses of biopsy specimens for pre-operational diagnosis are highly invasive and often difficult to apply to lung cancer patients. The purpose of this study was to evaluate the possible utility of determining epidermal growth factor receptor (EGFR) expression on exosomal membranes using a targeted ELISA with an anti-CD81 antibody as a capture antibody for lung cancer diagnosis. While soluble EGFR (sEGFR) levels in plasma were not remarkably different between lung cancer patients and normal controls, significantly higher exosomal EGFR expression levels were observed in 5/9 cancer cases compared to normal controls. These results suggest that measurement of exosomal protein levels could be useful for in vitro diagnosis, and that exosomal EGFR is a possible biomarker for characterization of lung cancer.