gebhart/patrepeval huggingface dataset:
Quality assessment of image patches distorted by image compression using crowdsourcing (2016)

Three experiments addressing the assessment of perceived image quality in a patch-based manner are compared for HEVC compression artifacts. It is shown that image patches of a size small as 128×128 pixel are large enough to evaluate the perceived image quality in a Degradation Category Rating (DCR) setting. Ratings obtained with 128×128 pixel sized images patches and 512×512 pixel sized images of the same spatial statistics show a correlation of r=0.99. Based on this finding, image quality assessment of 128×128 pixel sized image patches degraded by HEVC compression is compared for controlled lab environment and uncontrolled crowdsourcing settings. Although we find high overall correlation between the quality ratings obtained in the two environments, observers tend to give worse ratings in the crowdsourcing setting and for conditions of higher quality a reduction of correlation is observed. These findings have implications for choosing controlled vs. uncontrolled viewing conditions for image quality assessment for real-life applications.
ChemInform Abstract: Triply Convergent Synthesis of (‐)‐Prostaglandin E2 (VIIb). (1987)

ChemInformVolume 18, Issue 2 Natural Products ChemInform Abstract: Triply Convergent Synthesis of (-)-Prostaglandin E2 (VIIb). C. R. JOHNSON, C. R. JOHNSON Dep. Chem., Wayne State Univ., Detroit, MI 48202, USASearch for more papers by this authorT. D. PENNING, T. D. PENNING Dep. Chem., Wayne State Univ., Detroit, MI 48202, USASearch for more papers by this author C. R. JOHNSON, C. R. JOHNSON Dep. Chem., Wayne State Univ., Detroit, MI 48202, USASearch for more papers by this authorT. D. PENNING, T. D. PENNING Dep. Chem., Wayne State Univ., Detroit, MI 48202, USASearch for more papers by this author First published: January 13, 1987 https://doi.org/10.1002/chin.198702339Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume18, Issue2January 13, 1987 RelatedInformation
Method of amplitude data recovery in PMU measurements that considers synchronisation errors (2020)

The synchronised phasor measurement units (PMUs), serving as ‘GridEye’, provide data that improve the observability and controllability of the power grid due to its high accuracy and high‐upload rate. However, missing or abnormal data may seriously affect its applications. This study proposes a method to recover the missing or abnormal amplitude data in PMU measurements (i.e. the active power, reactive power, positive sequence current, and voltage amplitude), based on the historical PMU data obtained from both ends of the line, which is independent of the transmission line parameters and the phase angle that may be influenced by synchronisation. First, the issues in the quality of measured PMU data are analysed, and the motivation of the proposed method is stated. Then, a method to screen out the bad data from the historical data is proposed based on the density‐based spatial clustering of applications with noise. Furthermore, the model of data recovery is established, and the recovery method, which recovers the voltage amplitude, active power, reactive power, and current amplitude in sequence, using historical amplitude data to calculate related recovery coefficients is proposed. Finally, the effectiveness and practicability of the proposed method are verified by examples of simulation and measured data.
A Gas Chromatography/Electron Capture/Negative Chemical Ionization High-Resolution Mass Spectrometry Method for Analysis of Endogenous and Exogenous N7-(2-Hydroxyethyl)guanine in Rodents and Its Potential for Human Biological Monitoring (1999)

A gas chromatography/electron capture/negative chemical ionization high-resolution mass spectrometry (GC/EC/NCI-HRMS) method was developed for quantitating N7-(2-hydroxyethyl)guanine (N7-HEG) with excellent sensitivity and specificity. [4,5,6,8-(13)C(4)]-N7-HEG was synthesized, characterized, and quantitated using HPLC/electrospray ionization mass spectrometry (HPLC/ESI-MS) so it could serve as an internal standard. After being converted to its corresponding xanthine and derivatized with pentafluorobenzyl (PFB) bromide twice, the PFB derivative of N7-HEG was characterized using GC/EC/NCI-HRMS carried out at full scan mode. The most abundant fragment was at m/z 555, with a molecular formula of C(21)H(9)N(4)O(3)F(10), resulting from the loss of one PFB group. By monitoring m/z 555.0515 (analyte) and m/z 559.0649 (internal standard), this assay demonstrated a linear relationship over a range of 1 fmol to 1 pmol of N7-HEG versus 20 fmol of [(13)C(4)]-N7-HEG on column. The limit of detection (LOD) for the complete assay was 600 amol (S/N = 5) injected on column. The variation of this assay was within 15% from 1 to 20 fmol of N7-HEG versus 2 fmol of [(13)C(4)]-N7-HEG with four replications for each calibration standard. Two hundred to three hundred micrograms of spleen DNA of control rats and mice and 100 microg of spleen DNA of rats and mice exposed to 3000 ppm ethylene for 6 h/day for 5 days were analyzed using GC/EC/NCI-HRMS. The amounts of N7-HEG varied from 0.2 to 0.3 pmol/micromol of guanine in tissues of control rats. Ethylene-exposed animals had 5-15-fold higher N7-HEG levels than controls. This assay was able to quantitate N7-HEG in 25-30 microg of DNA from human lymphocytes with excellent specificity. This was due in part to human tissues having 10-15-fold higher amounts of endogenous N7-HEG than rodents. These results show that this GC/EC/NCI-HRMS method is highly sensitive and specific and can be used in biological monitoring and molecular dosimetry and molecular epidemiology studies.
The effect of external magnetic field on mark size during field emission assisted magnetic probe recording on CoNi/Pt multilayers (2005)

In this work, we characterize a heat-assisted magnetic recording process potentially suitable for proposed probe-based storage systems. A scanning tunneling microscope (STM) is used to locally heat a uniformly magnetized perpendicular recording medium via field emission current. The recording medium is a 30 nm thick CoNi/Pt multilayer film (H/sub C/ = 100 kA/m [1.2 kOe], M/sub S/ = 360 kA/m) with a 23 nm thick Pt seedlayer, fabricated on a bare Si substrate. Voltage pulses were applied between STM tip (made of Ir/Pt) and the medium to write marks with external magnetic field applied. A magnetic force microscope (MFM) is used to image marks. Mark size was measured as the FWHM of MFM phase signal. Experimental results show that mark size increases with increasing positive field and decreases with increasing negative field. A model is quantitatively simulate our experimental results and we are able to predict tip and medium configurations and applied powers that should permit marks appropriate for recording at 1 Tbit/in/sup 2/ and beyond.
Supplementary Figure Legends 1-2 from DNA Methylation and Complete Transcriptional Silencing of Cancer Genes Persist after Depletion of EZH2 (2023)

Supplementary Figure Legends 1-2 from DNA Methylation and Complete Transcriptional Silencing of Cancer Genes Persist after Depletion of EZH2
Deciphering the Plasma Proteome of Type 2 Diabetes (2020)

With an estimated prevalence of 463 million affected, type 2 diabetes represents a major challenge to health care systems worldwide. Analyzing the plasma proteomes of individuals with type 2 diabetes may illuminate hitherto unknown functional mechanisms underlying disease pathology. We assessed the associations between type 2 diabetes and &gt;1000 plasma proteins in the KORA (Cooperative health research in the Region of Augsburg) F4 cohort (n=993, 110 cases), with subsequent replication in the HUNT3 (Third wave of the Nord-Trøndelag Health Study) cohort (n=940, 149 cases). We computed logistic regression models adjusted for age, sex, BMI, smoking status and hypertension. Additionally, we investigated associations with incident type 2 diabetes and performed two-sample bi-directional Mendelian randomization (MR) analysis to prioritize our results. Association analysis of prevalent type 2 diabetes revealed 24 replicated proteins, of which eight are novel. Proteins showing association with incident type 2 diabetes were aminoacylase-1, growth hormone receptor, and insulin-like growth factor binding protein-2. Aminoacylase-1 was associated with both prevalent and incident type 2 diabetes. MR analysis yielded nominally significant causal effects of type 2 diabetes on cathepsin Z and rennin, both known to have roles in the pathophysiological pathways of cardiovascular disease, and of sex hormone-binding globulin on type 2 diabetes. In conclusion, our high-throughput proteomics study replicated previously reported type 2 diabetes-protein associations, and identified new candidate proteins possibly involved in the pathogenesis of type 2 diabetes.
Cr/sup 4+/:forsterite nanocrystalline glass-ceramic fiber (2001)

Summary form only given. Glass-ceramics are two-phase systems consisting of a base glass within which crystals are grown by heat treatment, a process known as ceramming. Recent progress on fiberization of these materials led to the demonstration of a rare earth doped fiber laser and amplifier with an efficiency uncompromised by the presence of the crystals embedded within the core of the single mode fiber. Transitions metal ions are notoriously inefficient when incorporated into a glass host, due to the difficulty of controlling the local environment, to which they are very sensitive. However to date, the properties of Cr/sup 4+/-doped glass-ceramic systems have received little attention, despite the apparent advantages of crystal site control. This paper investigates the fluorescence properties of Cr/sup 4+/-doped forsterite glass-ceramics and shows that many of the important characteristics of the single crystal are reproduced in the glass-ceramic system. Furthermore, many of the spectroscopic parameters are also observed in glass-ceramic fiber, highlighting the potential for a new class of fiber laser and amplifier made from transition metal-doped glass-ceramics.
Data-driven fluid simulations using regression forests (2015)

Traditional fluid simulations require large computational resources even for an average sized scene with the main bottleneck being a very small time step size, required to guarantee the stability of the solution. Despite a large progress in parallel computing and efficient algorithms for pressure computation in the recent years, realtime fluid simulations have been possible only under very restricted conditions. In this paper we propose a novel machine learning based approach, that formulates physics-based fluid simulation as a regression problem, estimating the acceleration of every particle for each frame. We designed a feature vector, directly modelling individual forces and constraints from the Navier-Stokes equations, giving the method strong generalization properties to reliably predict positions and velocities of particles in a large time step setting on yet unseen test videos. We used a regression forest to approximate the behaviour of particles observed in the large training set of simulations obtained using a traditional solver. Our GPU implementation led to a speed-up of one to three orders of magnitude compared to the state-of-the-art position-based fluid solver and runs in real-time for systems with up to 2 million particles.
In Vivo Modulation of Vaccine-Induced Immune Responses toward a Th1 Phenotype Increases Potency and Vaccine Effectiveness in a Herpes Simplex Virus Type 2 Mouse Model (1999)

ABSTRACT Several vaccines have been investigated experimentally in the herpes simplex virus type 2 (HSV-2) model system. While it is believed that CD4 + -T-cell responses are important for protection in general, the correlates of protection from HSV-2 infection are still under investigation. Recently, the use of molecular adjuvants to drive vaccine responses induced by DNA vaccines has been reported in a number of experimental systems. We sought to take advantage of this immunization model to gain insight into the correlates of immune protection in the HSV-2 mouse model system and to further explore DNA vaccine technology. To investigate whether the Th1- or Th2-type immune responses are more important for protection from HSV-2 infection, we codelivered the DNA expression construct encoding the HSV-2 gD protein with the gene plasmids encoding the Th1-type (interleukin-2 [IL-2], IL-12, IL-15, and IL-18) and Th2-type (IL-4 and IL-10) cytokines in an effort to drive immunity induced by vaccination. We then analyzed the modulatory effects of the vaccine on the resulting immune phenotype and on the mortality and the morbidity of the immunized animals following a lethal challenge with HSV-2. We observed that Th1 cytokine gene coadministration not only enhanced the survival rate but also reduced the frequency and severity of herpetic lesions following intravaginal HSV challenge. On the other hand, coinjection with Th2 cytokine genes increased the rate of mortality and morbidity of the challenged mice. Moreover, of the Th1-type cytokine genes tested, IL-12 was a particularly potent adjuvant for the gD DNA vaccination.
Competitive Impact of Nanotube Assembly and Contact Electrodes on the Performance of CNT-based FETs (2016)

We report the fabrication and characterization of highly dense field-effect-transistor (FET) arrays based on single-walled carbon nanotubes (SWCNTs). The nanotubes were sorted according to the electronic type by using density gradient ultracentrifugation (DGU). By employing dielectrophoresis (DEP), SWCNTs with enriched semiconducting (sc) content were systematically integrated as active elements into FETs. The performance of air-operating FETs was addressed via an extended statistic study involving both electrical and structural analyses. The competitive impact of nanotube purity and assembly as well as the metal electrode composition and a thermal treatment on the final device performance was shown. Regardless of the used sc-content, the device-to-device consistency was improved via employing annealing up to 250 °C for 1 h in a vacuum. The observed clockwise hysteresis, known so far only in connection with CNT–FETs built on ferroelectric substrates as well as electrolyte gated CNT–FETs, was found to reverse upon annealing. Moreover, a simple approach in producing air-stable ambipolar transistors is pointed out only via change of the adhesion layer for the Pd electrodes. The annealing study, repeated on such systems, supports the previous results and provides complementary information via a reliable monitoring of the off-state. Indications for a doping-like effect, which partially compromises the device performance in terms of threshold voltage shifts and increased off-state currents, are revealed and discussed.
Flexibility and Interoperability in CORBA Security (2000)

This paper will discuss the fundamental clash between flexibility and interoperability in CORBA security and in distributed object systems security in general. Also, the impact of flexibility and interoperability issues on the security of such systems will be covered. By presenting various relevant technical issues in CORBA security, this paper tries to identify where a reasonable trade-off between flexibility and interoperability is achieved and where CORBA security has unnecessary flexibility or interoperability limitations.
Needle Depth and Big-Bubble Success in Deep Anterior Lamellar Keratoplasty (2016)

BB formation in DALK is more successful if needle insertion and air injection occur at deeper corneal depth. However, ≥90% corneal depth was not necessary in this ex vivo model of DALK. SS-MIOCT can be used to accurately guide the needle in real time.
Pan, Bacchus et le sphinx. Une peinture murale d’époque romaine découverte à Die (2016)

International audience
ChemInform Abstract: AXIAL PREFERENCE OF A 2‐ANILINOSUBSTITUENT IN 4‐METHYL‐1,3,2‐DIOXAPHOSPHORINAN (1975)

Abstract NMR‐spektroskopischeUntersuchung des stereochemischen Verlaufs der Reaktion i von Anilin mit 2‐Chlor‐4‐methyl‐l ,3,2‐dioxaphosphorinan.
Diminution of the AML1 Transcription Factor Function Causes Differential Effects on the Fates of CD4 and CD8 Single-Positive T Cells (2000)

In the thymic cortex, T lymphocytes are positively selected to survive and committed either to the CD4 single-positive (SP) or the CD8 SP lineage. The SP cells then pass through a step of maturation in the medulla and are delivered to peripheral lymphoid tissues. We examined the role of AML1, the gene encoding a transcription factor, in the above processes by using the transgenic mice expressing a dominant interfering form of AML1 as well as mice targeted heterozygously for AML1. One phenotypic change seen in the AML1-diminished mice was the reduction in the numbers of both CD4 SP and CD8 SP thymocytes, reflecting the partial impairment of the transition from the double-positive to SP stage. In addition, distinct from the above abnormality, perturbed were several aspects of SP cells, including the maturation of SP thymocytes, the recent thymic emigration, and the proliferative responsiveness of peripheral T cells to TCR stimulation. Interestingly, the AML1 diminution caused inhibitory and enhancing effects on the CD4 SP and CD8 SP cells, respectively. These differential effects are most likely related to the reduction in the peripheral CD4 SP/CD8 SP ratio observed in the AML1-diminished mice. The AML1 transcription factor thus maintains the homeostasis of each SP subset by functioning at the later stages of T lymphocyte differentiation.
External short circuit fault diagnosis based on supervised statistical learning (2017)

This paper proposes a fault diagnosis method for external short circuit detection based on the supervised statistical learning. The maximum likelihood estimator is used to capture the statistical properties of the fault and non-fault datasets, and the Gaussian classifier is applied to distinguish the two states. Validation experiments demonstrate the good performance of the proposed method in dynamic conditions. Compared to the prevailing fault detection methods, this method does not require extensive modeling work, determines the fault completely based on the data in existing fault occurrence, and can be adopted easily with the trend of big data and connected vehicles.
A canine adenovirus type 2 vaccine vector confers protection against foot-and-mouth disease in guinea pigs (2018)

Vaccination is a key element in the control of foot-and-mouth disease (FMD). The majority of the antigenic sites that induce protective immune responses are localized on the FMD virus (FMDV) capsid that is formed by four virus-encoded structural proteins, VP1 to VP4. In the present study, recombinant canine adenovirus type 2 (CAV2)-based FMD vaccines, Cav-P1/3C R° and Cav-VP1 R°, respectively expressing the structural P1 precursor protein along with the non-structural 3C protein or expressing the structural VP1 protein of the FMDV strain O/FRA/1/2001, were evaluated as novel vaccines against FMD. A strong humoral immune response was elicited in guinea pigs (GP) following immunization with Cav-P1/3C R°, while administration of Cav-VP1 R° did not induce a satisfying antibody response in GP or mice. GP were then used as an experimental model for the determination of the protection afforded by the Cav-P1/3C R° vaccine against challenge with the FMDV strain O<sub>1</sub> Manisa/Turkey/1969. The Cav-P1/3C R° vaccine protected GP from generalized FMD to a similar extent as a high potency double-oil emulsion O<sub>1</sub> Manisa vaccine. The results of the present study show that CAV2-based vector vaccines can express immunogenic FMDV antigens and offer protection against generalized FMD in GP. This suggest that Cav-P1/3C R° FMDV vaccine may protect natural host species from FMD. In combination with an appropriate diagnostic test, the Cav-P1/3C R° FMDV vaccine may also serve as a marker vaccine to differentiate vaccinated from infected animals.
A structured, automated design procedure for systems integration sequential logic (2003)

A structured design procedure for systems integration sequential logic which is to be implemented on programmable logic controllers is presented. The procedure offers the advantages of producing intrinsically robust software which is very easy to understand and to modify as systems requirements change. The approach takes advantage of the sequential nature nature of processors to assure that the order of solution of the sequential logic equations is consistent with maximum speed and instantaneous correctness of the output states. The authors present examples of the basic elements of the structured design procedure from which any type of system integration can be implemented. An example is given of an industrial die cast molding machine system.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
UV‐Printable and Flexible Humidity Sensors Based on Conducting/Insulating Semi‐Interpenetrated Polymer Networks (2017)

Humidity sensors are of great interest in many fields because humidity plays a crucial role in several processes. Nevertheless, their application is often limited by the expensive fabrication and the stiffness of the substrates usually employed. In this work, novel UV‐curable and flexible humidity sensors based on semi‐interpenetrated polymer networks are fabricated. They can be prepared either as self‐standing sensors or applied on different bendable substrates. The fabrication consists of a simultaneous UV‐curing of an insulating network (acrylic or epoxy) and photopolymerization of conducting polypyrrole (PPy). The detection mechanism involves proton transfer on the PPy chains that can be macroscopically observed by electrical impedance variations. These devices show promising humidity‐sensing properties from 20 to 97% of relative humidity with a maximum response of about 180%. The dynamic sensing investigation proves that the recovery process can be tailored playing on the glass transition temperature and wettability of the films. The remarkable sensing capabilities of these sensors make them a valid alternative in many applications where printability and flexibility are required along with simple fabrication method consisting of one‐step synthesis.