gebhart/patrepeval huggingface dataset:
Vibrational relaxation and electronic quenching rate coefficients for BiF(A0+,v′) by SF6 (1988)

We have extended our kinetic data base for the A state of BiF to include SF6 as a collision partner. By applying a four level finite difference fitting routine to time-resolved fluorescence traces from v′=0–3, we have obtained rate coefficients for electronic quenching, and for vibrational relaxation within the A-state manifold. As was the case for our previous results in He and Ar, electronic quenching is slow in comparison to radiative decay. Vibrational relaxation does not show a simple v′ dependence, but rather, for the levels examined, increases markedly for higher v′. Our results confirm the suitability of SF6 as a bulk diluent in the proposed NF/BiF chemical laser system.
Economic and technical propositions for inter-domain services (2009)

The next challenge for carriers consists of proposing value-added services (e.g., videoconferencing) to users connected to remote domains. Such services cross several networks and require quality of service (QoS) guarantees. Establishing them would yield new earnings for transit and terminal domains. However, setting up such services is a non-trivial problem for technical, economic, and political reasons. The technical issues are essentially related to topology confidentiality, scalability, and heterogeneity-since carriers deploy different technologies-and to static interconnection processes for end-to-end QoS pricing, negotiating, provisioning, and monitoring. Economic and political reasons suggest that the most viable way to introduce value-added inter-carrier services is to develop dynamic carrier-cooperative processes with respect to carrier needs for confidentiality and independence. This paper depicts this inter-domain context and proposes an economics-based architecture to automatically establish inter-domain services. We also present different algorithmic solutions to improve the end-to-end QoS provisioning.
R2DP: A Universal and Automated Approach to Optimizing the Randomization Mechanisms of Differential Privacy for Utility Metrics with No Known Optimal Distributions (2020)

Differential privacy (DP) has emerged as a de facto standard privacy notion for a wide range of applications. Since the meaning of data utility in different applications may vastly differ, a key challenge is to find the optimal randomization mechanism, i.e., the distribution and its parameters, for a given utility metric. Existing works have identified the optimal distributions in some special cases, while leaving all other utility metrics (e.g., usefulness and graph distance) as open problems. Since existing works mostly rely on manual analysis to examine the search space of all distributions, it would be an expensive process to repeat such efforts for each utility metric. To address such deficiency, we propose a novel approach that can automatically optimize different utility metrics found in diverse applications under a common framework. Our key idea that, by regarding the variance of the injected noise itself as a random variable, a two-fold distribution may approximately cover the search space of all distributions. Therefore, we can automatically find distributions in this search space to optimize different utility metrics in a similar manner, simply by optimizing the parameters of the two-fold distribution. Specifically, we define a universal framework, namely, randomizing the randomization mechanism of differential privacy (R2DP), and we formally analyze its privacy and utility. Our experiments show that R2DP can provide better results than the baseline distribution (Laplace) for several utility metrics with no known optimal distributions, whereas our results asymptotically approach to the optimality for utility metrics having known optimal distributions. As a side benefit, the added degree of freedom introduced by the two-fold distribution allows R2DP to accommodate the preferences of both data owners and recipients.
47.1: Invited Paper: Combinatorial Studies on OLED Structures (2002)

Abstract The capabilities of combinatorial methods are presented in order to get a detailed understanding of the electrical and optical properties of organic light‐emitting devices (OLEDs), to optimize their performance and to provide reliable data for device modeling. We show results on multilayer OLEDs ranging from the conventional copper‐phthalocyanine (CuPc)/ N, N′‐di‐(naphtalene‐1‐yl) ‐N, N′‐diphenyl‐benzidine (NPB) and tris‐(8‐hydroxy‐quino‐linato) aluminum (Alq) tri‐layer device to double‐doped, deep‐red emitting OLEDs.
Multifunctional substrates for high-frequency applications (2003)

A substrate that is designed to suppress parasitic modes while at the same time provides high-Q filtering capability is presented. High-density circuits require the integration of multiple functions in very limited space. More specifically, with the design of three-dimensional (3-D) circuits, parasitic effects caused by the excitation of surface waves result in a serious degradation of performance and impose limitations on circuit density and performance. Herein, an effort is presented to use advanced design concepts to enable embedded functionality within a substrate. The presented substrate geometries can easily be extended to 3-D to allow for the development of system-in-a-package which incorporates a high-Q filter bank to provide effective frequency selectivity. To demonstrate this concept, resonators and filters in LTCC are designed, fabricated and measured. Resonators in LTCC with unloaded Q up to 428 were measured. A narrow-band 2-pole filter is realized to show that a function of a relatively high-Q can be incorporated into the packaging. The 2.28% filter has an insertion loss of 1.7 dB due to the low loss nature of the design. Simulation and measurement of the structures are presented with good agreement achieved.
Intramolecular oxidative coupling of diphenolic, monophenolic, and nonphenolic substrates (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIntramolecular oxidative coupling of diphenolic, monophenolic, and nonphenolic substratesMartin A. Schwartz, Bernard F. Rose, Robert A. Holton, Steven W. Scott, and Baburao VishnuvajjalaCite this: J. Am. Chem. Soc. 1977, 99, 8, 2571–2578Publication Date (Print):April 1, 1977Publication History Published online1 May 2002Published inissue 1 April 1977https://pubs.acs.org/doi/10.1021/ja00450a027https://doi.org/10.1021/ja00450a027research-articleACS PublicationsRequest reuse permissionsArticle Views784Altmetric-Citations66LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia (2001)

Acute promyelocytic leukemia (APL) is associated with chromosomal translocations, invariably involving the retinoic acid receptor alpha (RAR alpha) gene fused to one of several distinct loci, including the PML or PLZF genes, involved in t(15;17) or t(11;17), respectively. Patients with t(15;17) APL respond well to retinoic acid (RA) and other treatments, whereas those with t(11;17) APL do not. The PML-RAR alpha and PLZF-RAR alpha fusion oncoproteins function as aberrant transcriptional repressors, in part by recruiting nuclear receptor-transcriptional corepressors and histone deacetylases (HDACs). Transgenic mice harboring the RAR alpha fusion genes develop forms of leukemia that faithfully recapitulate both the clinical features and the response to RA observed in humans with the corresponding translocations. Here, we investigated the effects of HDAC inhibitors (HDACIs) in vitro and in these animal models. In cells from PLZF-RAR alpha/RAR alpha-PLZF transgenic mice and cells harboring t(15;17), HDACIs induced apoptosis and dramatic growth inhibition, effects that could be potentiated by RA. HDACIs also increased RA-induced differentiation. HDACIs, but not RA, induced accumulation of acetylated histones. Using microarray analysis, we identified genes induced by RA, HDACIs, or both together. In combination with RA, all HDACIs tested overcame the transcriptional repression exerted by the RAR alpha fusion oncoproteins. In vivo, HDACIs induced accumulation of acetylated histones in target organs. Strikingly, this combination of agents induced leukemia remission and prolonged survival, without apparent toxic side effects.
Encapsulation of Inorganic Particles with Nanostructured Cellulose (2007)

Abstract Inorganic‐cellulose core‐shell and hollow cellulose nanoparticles were prepared by self‐encapsulation with regenerated cellulose in a poly(acrylic acid) hydrogel layer surrounding inorganic particle templates in N ‐methylmorpholine oxide (NMMO) (4‐methylmorpholine N ‐oxide) monohydrate solution. The hydrogel layer surrounding the inorganic particle surface plays a decisive role in the core‐shell formation. The core‐shell nanostructures were characterized using TEM, SEM, and X‐ray diffraction (XRD). The cellulose shell was found to be composed of cellulose spheres or nodules with dimensions of approximately 30 nm. Individual, regenerated cellulose nanoparticles were also synthesized by addition of nonsolvent under agitation to dilute solutions of cellulose dissolved in NMMO. The effects of the rate of addition of water (the nonsolvent) on the nanostructure, morphology and crystallinity of the regenerated cellulose nanoparticles were studied. The results indicate that the faster the water‐addition rate, the smaller the cellulose nanoparticles formed. magnified image
Diseño de una antena multibanda con ranuras en el plano de masa: una técnica para facilitar la integración de la línea de alimentación (2009)

The integration of transmission lines is a difficult task due to the presence of slots. In order to facilitate the integration of the feeding transmission line which connects the antenna with the RF-module, this research proposes a ground plane modification using central slots. Numerical simulation using MoM is used to understand the effect of the slots on the ground plane and several prototypes have been built to validate the present technique. Through this technique is possible to obtain a multiband antenna while keeping the same antenna geometry, small volume and simplifying the PCB (Printed Circuit Board) design.
Catalytic combustion of coal-derived liquids (1981)

A noble metal catalytic reactor was tested with three grades of SRC 2 coal derived liquids, naphtha, middle distillate, and a blend of three parts middle distillate to one part heavy distillate. A petroleum derived number 2 diesel fuel was also tested to provide a direct comparison. The catalytic reactor was tested at inlet temperatures from 600 to 800 K, reference velocities from 10 to 20 m/s, lean fuel air ratios, and a pressure of 3 x 10 to the 5th power Pa. Compared to the diesel, the naphtha gave slightly better combustion efficiency, the middle distillate was almost identical, and the middle heavy blend was slightly poorer. The coal derived liquid fuels contained from 0.58 to 0.95 percent nitrogen by weight. Conversion of fuel nitrogen to NOx was approximately 75 percent for all three grades of the coal derived liquids.
Evaporative cooling in microfluidic channels (2006)

Evaporative cooling is an effective and energy efficient way to rapidly remove heat from a system. Specifically, evaporative cooling in microfluidic channels can provide a cost-effective solution for the cooling of electronic devices and chemical reactors. Here we present microfluidic devices fabricated by using soft-lithography techniques to form simple fluidic junctions between channels carrying refrigerant and channels carrying N2 gas. The effects of channel geometry and delivery pressure on the performance of refrigeration through vaporization of acetone, isopropyl alcohol, and ethyl ether were characterized. By varying gas inlet pressures, refrigerants, and angles of the microfluidic junctions, optimal cooling conditions were found. Refrigeration rates in excess of 40°C∕s were measured, and long lasting subzero cooling in the junction could be observed.
Deep Learning and Gaussian Process based Band Assignment in Dual Band Systems. (2019)

We consider the band assignment (BA) problem in dual-band systems, where the basestation (BS) chooses one of the two available frequency bands (centimeter-wave and millimeter-wave bands) to communicate with the user equipment (UE). While the millimeter-wave band might offer higher data rate, there is a significant probability of outage during which the communication should be carried on the (more reliable) centimeter-wave band. We consider two variations of the BA problem, one-shot and sequential BA. For the former the BS uses only the currently observed information to decide whether to switch to the other frequency band, for the sequential BA, the BS uses a window of previously observed information to predict the best band for a future time step. We provide two approaches to solve the BA problem, (i) a deep learning approach that is based on Long Short Term Memory and/or multi-layer Neural Networks, and (ii) a Gaussian Process based approach, which relies on the assumption that the channel states are jointly Gaussian. We compare the achieved performances to several benchmarks in two environments: (i) a stochastic environment, and (ii) microcellular outdoor channels obtained by ray-tracing. In general, the deep learning solution shows superior performance in both environments.
Tetraarylphosphonium-Supported Carbodiimide Reagents:  Synthesis, Structure Optimization and Applications (2008)

New tetraarylphosphonium (TAP)-supported alkyl- and arylcarbodiimides were synthesized and used as coupling reagents for esterification reactions, amidation reactions and dehydration reactions of hydroxyesters. Taking advantage of the solubility properties imparted by the tetraarylphosphonium unit, a simple precipitation and filtration allowed complete separation of the urea by-products. This paper describes the structure optimization study of the various TAP-supported carbodiimide reagents to obtain the desired reactivity and solubility profile. Furthermore, we have demonstrated that the diimide reagent can be regenerated from the urea to recycle the reagents.
Local grain orientation and strain in polycrystalline YBa2Cu3O7−δ superconductor thin films measured by Raman spectroscopy (2001)

We report direct measurements of local grain orientation and residual strain in polycrystalline, C-axis oriented thin YBa2Cu3O7−δ superconducting films using polarized Raman spectroscopy. Strain dependence of the Ag Raman active mode at 335 cm−1 was calibrated and used to measure local strain in the films. Our data showed that high quality films are associated with the connected path of uniform grain orientation (single crystal-like) across the film and uniform residual strain in the range of −0.3%. Nonuniform grain orientation or high angle grain boundaries and nonuniform local strains were associated with low quality films.
Crystal structure of tetrachloro-bis(pyrazole)tungsten(IV) dimethoxyethane solvate, WCl4(C3H4N2)2 · (CH3OCH2)2 (2005)

Article Crystal structure of tetrachloro-bis(pyrazole)tungsten(IV) dimethoxyethane solvate, WCl4(C3H4N2)2 · (CH3OCH2)2 was published on April 1, 2005 in the journal Zeitschrift für Kristallographie - New Crystal Structures (volume 220, issue 1-4).
Rate of hot flashes in patients with advanced prostate cancer treated with GTx-758. (2013)

129 Background: When androgen deprivation therapy (ADT) for prostate cancer was first developed, life expectancy for men with advanced disease was short and the systemic effects were of limited relevance. GTx-758 is a selective ERα agonist that effects serum total testosterone (T), free T, SHBG and PSA. Herein we compare the effects of GTx-758 and leuprolide on hot flashes, one of the common side effects in men on ADT. Methods: In a Phase II study (G200705), men with advanced prostate cancer (n=159) received 1000 mg or 2000 mg of GTx-758 daily or leuprolide. Utilizing a standardized instrument to measure the frequency and severity of hot flashes, data was compiled at baseline, day 28 and day 90. The number of men experiencing hot flashes were those reporting any in the period between the respective time point and the prior patient visit. All p values describe the comparison of both GTx-758 treatment groups to the leuprolide treated men. Results: At the baseline, there were no significant differences in the number of men reporting hot flashes in any of the treatment groups (p=0.065). The percentage of men who experienced a hot flash while receiving leuprolide increased significantly to 60.4% (p&lt;0.0001) by Day 28 and increased further to 80.9% (p&lt;0.0001) by Day 90. Although some subjects experienced hot flashes while receiving GTx-758, these men were a significantly lower percentage, 18.8 and 5.6% at the 1000 mg and 2000 mg doses of GTx-758 respectively at day 90. As a result of an increased risk of venous thromboembolic events (VTEs) at these higher doses of GTx-758, the trial was stopped prior to its completion and not all of the men on the study reached the 90 day treatment date (99 evaluable). Conclusions: Men with advanced prostate cancer, receiving GTx-758 experienced a greater than 4-fold reduction in their reported hot flashes at day 90. Since hot flashes are a major side effect that impacts the quality of life in men on ADT, the ability to significantly decrease their likelihood would seem to be of great benefit. A Phase II clinical trial utilizing lower doses of GTx-758 (G200712) is currently being performed that will determine if similar effects on serum free testosterone, PSA and hot flashes can be shown with a lower rate of VTEs. Clinical trial information: NCT01326312.
Hot-Wire Chemical Vapour Deposition for Silicon Nitride Waveguides (2016)

In this work, we demonstrate the use of HWCVD as an alternative technique to grow SiN layers for photonic waveguides at temperatures &lt;400ºC. In particular, the effect of the ammonia flow and the filament temperature on the material structure, optical properties and propagation losses of the deposited films was investigated. SiN layers with good thickness uniformity, roughness as low as 0.61nm and H concentration as low as 10.4x10 21 atoms/cm 3 were obtained. Waveguides fabricated on the studied materials exhibited losses as low as 7.1 and 12.3 dB/cm at 1310 and 1550nm respectively.
Radical Prostatectomy for Clinically Localized, High Risk Prostate Cancer: Critical Analysis of Risk Assessment Methods (2007)

Patients diagnosed with high risk cancer by currently available definitions do not have a uniformly poor prognosis after radical prostatectomy. Many cancers classified clinically as high risk are actually confined to the prostate pathologically. The risk of extraprostatic disease and prostate specific antigen relapse varies greatly depending on the definition used.
Improved Multiscale Entropy Technique with Nearest-Neighbor Moving-Average Kernel for Nonlinear and Nonstationary Short-Time Biomedical Signal Analysis (2018)

Analysis of biomedical signals can yield invaluable information for prognosis, diagnosis, therapy evaluation, risk assessment, and disease prevention which is often recorded as short time series data that challenges existing complexity classification algorithms such as Shannon entropy (SE) and other techniques. The purpose of this study was to improve previously developed multiscale entropy (MSE) technique by incorporating nearest-neighbor moving-average kernel, which can be used for analysis of nonlinear and non-stationary short time series physiological data. The approach was tested for robustness with respect to noise analysis using simulated sinusoidal and ECG waveforms. Feasibility of MSE to discriminate between normal sinus rhythm (NSR) and atrial fibrillation (AF) was tested on a single-lead ECG. In addition, the MSE algorithm was applied to identify pivot points of rotors that were induced in <i>ex vivo</i> isolated rabbit hearts. The improved MSE technique robustly estimated the complexity of the signal compared to that of SE with various noises, discriminated NSR and AF on single-lead ECG, and precisely identified the pivot points of <i>ex vivo</i> rotors by providing better contrast between the rotor core and the peripheral region. The improved MSE technique can provide efficient complexity analysis of variety of nonlinear and nonstationary short-time biomedical signals.
A Noninvasive Method for Assessing Oocyte Competency (2020)

There is an increasing demand to evaluate oocyte competency and viability for oocyte cryopreservation and use for in vitro fertilization. Oocytes suffer decreased survival of cryopreservation as compared to embryos, due to physical characteristics of the oocyte. The objective of this study is to determine if a specific gravity device (SGD) can estimate oocyte viability based on oocyte descent through the buoyancy system. All experiments were performed in a research laboratory with a randomized block design with repeated measures. Three hundred-seventy-six oocytes were collected from seven mice and randomly assigned to one of four treatments: exposure to 60C for 30 min, acidified media for 1h, ethylene glycol-glycerol cryoprotectant for 1h, or standard culture to serve as control. To further analyze the relationship between oocyte descent time and viability, 98 additional oocytes were passed through SGD before and after treatment. Oocytes were stained with Coomassie Blue to determine membrane permeability and estimate viability based on treatment. Oocytes treated with 60C heat, acidified media and ethylene glycol/ glycerol cryoprotectant solution demonstrated altered descent times from control and pre-treatment oocytes (P&lt;0.05). Oocytes exposed to heat and cryoprotectants descended more rapidly through SGD than control and pre-treatment oocytes (P&lt;0.05). Oocytes treated with acidified media descended more slowly through SGD (P&lt;0.05). Permeation of stain into oocytes exposed to lethal treatments confirmed changes in membrane integrity post-treatment and further indicates SGD can detect such shifts. This suggests SGD can predict competency between live and dead oocytes. In conclusion, SGD can detect shifts in oocyte density due to altered membrane permeability, which can suggest information about oocyte competency. This information can help differentiate between high- and low-quality fresh oocytes to help select which oocytes to freeze and result in improved oocyte cryopreservation and fertilization.