gebhart/patrepeval huggingface dataset:
Risk Stratification Algorithm for Management of Head-Neck Taper Tribocorrosion in Patients with Metal-on-Polyethylene Total Hip Arthroplasty (2021)

Adverse local tissue reactions (ALTRs) were initially reported as complications associated with metal-on-metal (MoM) bearings; however, there is increasing concern regarding the occurrence of adverse local tissue reactions from mechanically assisted crevice corrosion (MACC) at the femoral head-neck junction or between other modular junctions of the implant containing cobalt chromium parts in patients with metal-on-polyethylene (MoP) bearings. ALTR due to MACC at the head-neck junction has primarily been reported in association with cobalt chromium alloy femoral heads. As pain following total hip arthroplasty may have various intrinsic and extrinsic causes, a systematic approach to evaluation (risk stratification algorithm) based on the currently available data is recommended to optimize patient management. Evaluation should begin by ruling out common causes of pain, including component loosening and periprosthetic joint infection. While specialized tests such as blood metal analysis and metal artifact reduction sequence magnetic resonance imaging (MARS MRI) are useful modalities in evaluating for ALTRs, over-reliance on any single investigative tool in the clinical decision-making process should be avoided. There should be a low threshold to perform a systematic evaluation for ALTR due to MACC in patients with metal-on-polyethylene total hip arthroplasty as early recognition and diagnosis is critical, as delays in appropriate treatment initiation may result in soft-tissue damage, which complicates surgical treatment and is associated with a higher risk of complications and poorer patient outcomes.
DYNAMOMETER EVALUATION OF PLASMA-CATALYST FOR DIESEL NOX REDUCTION (2003)

A three-stage plasma-catalyst system was developed and tested on an engine dynamometer. Previous laboratory testing suggested high NOx efficiency could be obtained. With hexene reductant added to the exhaust, over 90% NOx reduction was observed. However, with diesel or Fischer-Tropsch reductant the catalyst efficiency rapidly dropped off. Heating the catalyst in air removed brown deposit from the surface and restored conversion efficiency. Following the engine tests, the used catalysts were evaluated. BET surface area decreased, and TPD revealed significant storage. This storage appears to be partly unburned diesel fuel that can be removed by heating to around 250-300 C, and partly hydrocarbons bonded to the surface that remain in place until 450-500 C. Laboratory testing with propene reductant demonstrated that the catalyst regains efficiency slowly even when operating temperature does not exceed 300 C. This suggests that control strategies may be able to regenerate the catalyst by occasional moderate heating.
High-resolution electrohydrodynamic jet printing of small-molecule organic light-emitting diodes (2015)

The development of alternative organic light-emitting diode (OLED) fabrication technologies for high-definition and low-cost displays is an important research topic as conventional fine metal mask-assisted vacuum evaporation has reached its limit to reduce pixel sizes and manufacturing costs. Here, we report an electrohydrodynamic jet (e-jet) printing method to fabricate small-molecule OLED pixels with high resolution (pixel width of 5 μm), which significantly exceeds the resolutions of conventional inkjet or commercial OLED display pixels. In addition, we print small-molecule emitting materials which provide a significant advantage in terms of device efficiency and lifetime compared to those with polymers.
Mice Overexpressing Both Human Angiotensinogen and Human Renin as a Model of Superimposed Preeclampsia on Chronic Hypertension (2009)

Preeclampsia is the major cause of maternal and fetal mortality/morbidity. Because hypertension is an important risk factor for preeclampsia, we investigated whether hypertensive mice that overexpress human renin and angiotensinogen develop superimposed preeclampsia. Given that the mechanisms underlying this disease are still poorly understood, animal models are of great use for elucidation. Blood pressure and proteinuria were measured by telemetry and ELISA, respectively. Heart function was evaluated by echocardiography, whereas pathological cardiac hypertrophy-related genes were assessed by real-time PCR. Soluble fms-like tyrosine kinase 1 plasma concentrations were quantitated by ELISA and placental expression by real-time PCR. Transgenic mice develop de novo proteinuria during gestation and marked blood pressure elevation, which are hallmarks of superimposed preeclampsia on chronic hypertension. Abnormal placentation present in these mothers produced a significant decrease in pup and placental weight and was associated with an increased placental expression of soluble fms-like tyrosine kinase 1. We also found heightened circulating levels of this receptor, when adjusted for placental mass, as has been observed in women who suffer from preeclampsia. Cardiac hypertrophy could be observed in the transgenic mice and was exacerbated by gestation. As a result, heart function was significantly decreased, and markers of pathological hypertrophy were increased. Our data, thus, confirm the characterization of a new model of superimposed preeclampsia on chronic hypertension. Because chronically hypertensive women are at risk of developing the pathology, our model reflects a clinical reality and is, thus, an excellent tool to elucidate the molecular mechanisms triggering this disease.
Nanocomposites: Flexible and Large‐Area Nanocomposite Generators Based on Lead Zirconate Titanate Particles and Carbon Nanotubes (Adv. Energy Mater. 12/2013) (2013)

A lead zirconate titanate (PZT)-based nanocomposite generator device is produced using a simple, lowcost, and scalable bar-coating method. As reported by Keon Jae Lee and co-workers on page 1539, flexible energy harvesting and wireless sensor networks can be realized using this high-performance, large-area nanocomposite generator. Energy harvesting systems driven by transportation and human biomechanical motions are also reported.
Bacterial Aggregation Triggered by Fibril Forming Tryptophan-Rich Sequences: Effects of Peptide Side Chain and Membrane Phospholipids (2020)

The influence of side chain residue and phospholipid characteristics of the cytoplasmic membrane upon the fibrillation and bacterial aggregation of arginine (Arg) and tryptophan (Trp) rich antimicrobial peptides (AMPs) has not been well described to date. Here, we utilized the structural advantages of HHC-10 and <sup>4Har</sup>HHC-10 (Har, l-homoarginine) that are highly active Trp-rich AMPs and investigated their fibril formation and activity behavior against bacteria. The peptides revealed time-dependent self-assembly of polyproline II (PPII) α-helices, but by comparison, <sup>4Har</sup>HHC-10 tended to form higher ordered fibrils due to relatively strong cation-π stacking of Trp with Har residue. Both peptides rapidly killed <i>S. aureus</i> and <i>E. coli</i> at their MICs and caused aggregation of bacteria at higher concentrations. This bacterial aggregation was accompanied by the formation of morphologically distinct electron-dense nanostructures, likely including but not limited to peptides alone. Both HHC-10-derived peptides caused blebs and buds in the <i>E. coli</i> membrane that are rich in POPE phospholipid that promotes negative curvature. However, the main population of <i>S. aureus</i> cells retained their cocci structure upon treatment with HHC peptides even at concentration higher than the MICs. In contrast, the cell aggregation was not induced by HHC fibrils that were most likely stabilized through intra-/intermolecular cation-π stacking. It is proposed that masking of these interactions might have resulted in diminished membrane association/insertion of the HHC nanostructures. The peptides caused aggregation of POPC/POPG (1/3) and POPE/POPG (3/1) liposomes. Nonetheless, disaggregation of the former vesicles was observed at ratios of lipid to peptide of greater than 6 and 24 for HHC-10 and <sup>4Har</sup>HHC-10, respectively. Collectively, our results revealed dose-dependent bacterial aggregation mediated by Trp-rich AMPs that was profoundly influenced by the degree of peptide's self-association and the composition and intrinsic curvature of the cytoplasmic membrane lipids.
Secure mobile social networks using USIM in a closed environment (2012)

Online social networking and corresponding mobile based applications are gaining popularity and now considered a well-integrated service within mobile devices. Basic security mechanisms normally based on passwords for the authentication of social-network users are widely deployed and poses a threat for the user security. In particular, for dedicated social groups with high confidentiality and privacy demands, stronger and user friendly principles for the authentication and identification of group members are needed. On the other hand, most of the mobile units already provide strong authentication procedures through the USIM/ISIM module. This paper explores how to build an architectural framework for secure enrollment and identification of group members in dedicated closed social groups using the USIM/SIM authentication and in particular, the 3GPP Generic Authentication Architecture (GAA), which is built upon the USIM/SIM capabilities. One part of the research is to identify the marketable use-cases with corresponding security challenges to fulfill the requirements that extend beyond the online connectivity. This paper proposes a secure identification design to satisfy the security dimensions for both online and offline peers. We have also implemented an initial proof of the concept prototype to simulate the secure identification procedure based on the proposed design. Our implementation has demonstrated the flexibility of the solution to be applied independently for applications requiring secure identification.
High-speed ultrasound imaging in dense suspensions reveals impact-activated solidification due to dynamic shear jamming (2016)

A remarkable property of dense suspensions is that they can transform from liquid-like at rest to solid-like under sudden impact. Previous work showed that this impact-induced solidification involves rapidly moving jamming fronts; however, details of this process have remained unresolved. Here we use high-speed ultrasound imaging to probe non-invasively how the interior of a dense suspension responds to impact. Measuring the speed of sound we demonstrate that the solidification proceeds without a detectable increase in packing fraction, and imaging the evolving flow field we find that the shear intensity is maximized right at the jamming front. Taken together, this provides direct experimental evidence for jamming by shear, rather than densification, as driving the transformation to solid-like behaviour. On the basis of these findings we propose a new model to explain the anisotropy in the propagation speed of the fronts and delineate the onset conditions for dynamic shear jamming in suspensions.
Unsupervised image segmentation based on local pixel clustering and low-level region merging (2016)

Heterogeneous image segmentation is one of the most important tasks in image processing. It consists in partitioning the image into a set of disjoint regions. In this paper, we propose a new unsupervised image segmentation method that we call Unsupervised Image Segmentation (UIS). Our proposal performs an efficient image partition efficiently into primitive regions. This process is ensured by a local adaptive Kmeans and a novel centroids initialization. Then, similar sets are agglomerated to form homogeneous regions. For that, a low-level feature merging is employed according to a hierarchical linkage approach. Finally, in case of over-segmentation, appearing outlier regions are removed using a post process stage. Therefore, the UIS method allows to determine automatically the image region number. Indeed, it extends the Kmeans clustering to obtain meaningful regions. Several experiments were conducted using two heterogeneous image datasets. A comparison with well-known segmentation methods was also performed using the Liu's factor measure.
Novel computer-aided diagnosis of mesothelioma using nuclear structure of mesothelial cells in effusion cytology specimens (2014)

diagnostic standard is a pleural biopsy with subsequent histologic examination of the tissue demonstrating invasion by the tumor. The diagnostic tissue is obtained through thoracoscopy or open thoracotomy, both being highly invasive procedures. Thoracocenthesis, or removal of effusion fluid from the pleural space, is a far less invasive procedure that can provide material for cytological examination. However, it is insufficient to definitively confirm or exclude the diagnosis of malignant mesothelioma, since tissue invasion cannot be determined. In this study, we present a computerized method to detect and classify malignant mesothelioma based on the nuclear chromatin distribution from digital images of mesothelial cells in effusion cytology specimens. Our method aims at determining whether a set of nuclei belonging to a patient, obtained from effusion fluid images using image segmentation, is benign or malignant, and has a potential to eliminate the need for tissue biopsy. This method is performed by quantifying chromatin morphology of cells using the optimal transportation (Kantorovich–Wasserstein) metric in combination with the modified Fisher discriminant analysis, a k-nearest neighborhood classification, and a simple voting strategy. Our results show that we can classify the data of 10 different human cases with 100% accuracy after blind cross validation. We conclude that nuclear structure alone contains enough information to classify the malignant mesothelioma. We also conclude that the distribution of chromatin seems to be a discriminating feature between nuclei of benign and malignant mesothelioma cells.
Skinny trace compensation methodology for high speed serial interface (2012)

Skinny trace compensation is a simple yet effective technique for overcoming capacitive impedance discontinuities on high speed channels. This paper provides a comprehensive system-level modeling and analysis methodology for implementing this technique on high speed serial interface. System level simulation correlation to laboratory measurement for the HDMI (High Definition Multimedia Interface) interface on a real high speed low power mobile microprocessor SOC (System on Chip) design is presented.
A provably convergent alternating minimization method for mean field inference (2015)

Mean-Field is an efficient way to approximate a posterior distribution in complex graphical models and constitutes the most popular class of Bayesian variational approximation methods. In most applications, the mean field distribution parameters are computed using an alternate coordinate minimization. However, the convergence properties of this algorithm remain unclear. In this paper, we show how, by adding an appropriate penalization term, we can guarantee convergence to a critical point, while keeping a closed form update at each step. A convergence rate estimate can also be derived based on recent results in non-convex optimization.
EPR spectra of lead(3+) and silver(0) in glass (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEPR spectra of lead(3+) and silver(0) in glassHideo Hosono, Junji Nishii, Hiroshi Kawazoe, Takafumi Kanazawa, and Kazuo AmetaniCite this: J. Phys. Chem. 1980, 84, 18, 2316–2319Publication Date (Print):September 1, 1980Publication History Published online1 May 2002Published inissue 1 September 1980https://pubs.acs.org/doi/10.1021/j100455a021https://doi.org/10.1021/j100455a021research-articleACS PublicationsRequest reuse permissionsArticle Views187Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Effects of Design Parameters on Root Stresses of Thin-Rimmed Helical Internal Gears with Asymmetric Web Arrangement in Mesh. (1997)

This paper presents a study on the effects of design parameters (rim thicMness, standard pressure angle, number of teeth, and face width) on root stresses of a meshed thin-rimmed helical internal gear with an asymmetric web arrangement for a planetary gear unit of the automatic transmission of automobile. The tooth deflections of the thin-rimmed helical internal gear with an asymmetric web arrangement of various design parameters due to a concentrated load were calculated by the three-dimensional finite-element method (3D-FEM). On the basis of the calculated results, approximate equations for the influence function of the tooth deflection were derived. The load sharing factor and the load distribution on the contact line of the thin-rimmed helical internal gears in mesh were calculated using these approximate equations and Kubo and Umezawa's method. The root stress of the thin-rimmed helical internal gear under the distributed load was calculated using the 3D-FEM. and the effect of the design parameters on the root stress was determined. Furthermore, a practical formula for the maximum root stress of the thin-rimmed helical internal gear with asymmetric web arrangement in mesh was derived.
Microfluidic chips for mass spectrometry‐based proteomics (2009)

Microfluidic devices coupled to mass spectrometers have emerged as excellent tools for solving the complex analytical challenges associated with the field of proteomics. Current proteome identification procedures are accomplished through a series of steps that require many hours of labor-intensive work. Microfluidics can play an important role in proteomic sample preparation steps prior to mass spectral identification such as sample cleanup, digestion, and separations due to its ability to handle small sample quantities with the potential for high-throughput parallel analysis. To utilize microfluidic devices for proteomic analysis, an efficient interface between the microchip and the mass spectrometer is required. This tutorial provides an overview of the technologies and applications of microfluidic chips coupled to mass spectrometry for proteome analysis. Various approaches for combining microfluidic devices with electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI) are summarized and applications of chip-based separations and digestion technologies to proteomic analysis are presented.
Evidence for the efficacy of PlGF inhibition in age‐related macular degeneration (2010)

Abstract Purpose We previously showed that an anti‐PlGF antibody (5D11D4) inhibits choroidal neovascularization (CNV) in a mouse model of AMD. An additive effect was shown in combination therapy with an anti‐VEGFR antibody. Specificity of 5D11D4 was assessed in this study. Methods CNV was induced in mice by placing 3 laser burns on the choroid. Mice with a PlGF deficiency or a lacking tyrosin kinase domain of the Flt‐1R or with a knock‐down of the monocyte chemoattractive protein were generated. The optimal dose of 25mg/kg of 5D11D4 was injected in all mice ip. 3 times a week. Results In a first experiment, loss of PlGF inhibited CNV. However, administration of 5D11D4 to PlGF‐/‐ mice did not inhibit CNV further than in control‐treated PlGF‐/‐ mice, indicating that 5D11D4 did not have off‐target effects. Second, Ccl2‐/‐ mice developed a CNV lesion that was slightly larger than in WT mice within 14 days after laser‐injury. Notably, 5D11D4 was able to inhibit CNV again by 53%. Third, we investigated whether PlGF signaling works specifically through Flt1 in CNV. FITC‐dextran perfused flatmounts revealed that CNV lesions were indeed reduced by 70% in Flt1‐TK‐/‐ mice, comparably as observed in PlGF‐/‐ mice. 5D11D4 was unable to inhibit CNV in Flt1‐TK‐/‐ mice any further. Fourth, we also tested the murine anti‐human PlGF mAb 16D3 in humanized PlGF‐/‐ mice. Human PlGF‐2 increased laser‐induced CNV after 5 days, but this increase was again blocked by 16D3. And finally, of two other anti‐mPlGF mAbs, 3C7A8 and 12H6B6, the first one inhibited CNV, while 12H6B6 was ineffective Conclusion We have proven that 5D11D4 specifically inhibits laser‐induced CNV formation, in different transgenic models and that this effect is mediated via the Flt1 receptor.
MATERIAL PROPERTY TABLES (2006)

You have accessInternational Plastics HandbookJun 2006MATERIAL PROPERTY TABLESTim A. Osswald, Erwin Baur, Sigrid Brinkmann, Karl Oberbach, Ernst SchmachtenbergTim A. Osswald, Erwin Baur, Sigrid Brinkmann, Karl Oberbach, Ernst Schmachtenberghttps://doi.org/10.3139/9783446407923.bmSectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF ShareFacebookTwitterEmailLinkedIn previous chapter FiguresReferencesRelatedDetails 2006Pages: 717-902Print ISBN: 978-3-446-22905-1eISBN: 978-3-446-40792-3 Copyright & Permissions© 2006 Carl Hanser Verlag GmbH & Co. KGPDF DownloadLoading ...
Effective index method in modeling of high-index-contrast planar photonic crystals (2004)

In this paper, a novel effective index method for modeling high index contrast planar photonic crystals is introduced. In this effective index method, the frequency axis is divided into many regions, and the effective index for each region is obtained using the central frequency of this region. Dispersion relationship in a wide frequency region can then be calculated using the effective index for each region to obtain the states in this region with a 2-D simulation and integrating all states in all frequency regions. The validity of this effective index method in approximating an intense three-dimensional (3-D) simulation required by the finite thickness of planar photonic crystals with a less intense two-dimensional simulation is examined. As an example, this method is applied to calculate the band diagram of a planar photonic crystal waveguide. By comparing with the results obtained with the full 3D simulation, we find that this method is valid for all states below the light cone in many bands, and the wider the waveguide, the more the number of bands, which agree with the full 3D results.
ChemInform Abstract: Preparation of a Fluorous Chiral BINOL Derivative and Application to an Asymmetric Protonation Reaction. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.