gebhart/patrepeval huggingface dataset:
DEUCE (2015)

Phase Change Memory (PCM) is an emerging Non Volatile Memory (NVM) technology that has the potential to provide scalable high-density memory systems. While the non-volatility of PCM is a desirable property in order to save leakage power, it also has the undesirable effect of making PCM main memories susceptible to newer modes of security vulnerabilities, for example, accessibility to sensitive data if a PCM DIMM gets stolen. PCM memories can be made secure by encrypting the data. Unfortunately, such encryption comes with a significant overhead in terms of bits written to PCM memory, causing half of the bits in the line to change on every write, even if the actual number of bits being written to memory is small. Our studies show that a typical writeback modifies, on average, only 12% of the bits in the cacheline. Thus, encryption causes almost a 4x increase in the number of bits written to PCM memories. Such extraneous bit writes cause significant increase in write power, reduction in write endurance, and reduction in write bandwidth. To provide the benefit of secure memory in a write efficient manner this paper proposes Dual Counter Encryption (DEUCE). DEUCE is based on the observation that a typical writeback only changes a few words, so DEUCE reencrypts only the words that have changed. We show that DEUCE reduces the number of modified bits per writeback for a secure memory from 50% to 24%, which improves performance by 27% and increases lifetime by 2x.
Saliva and serum biomarkers in periodontitis and coronary artery disease (2018)

MMP-8, MMP-9, TIMP-1and MPO are valuable biomarkers for both ACS and periodontitis, but the selection of sample material is crucial; serum is suitable for ACS and saliva for periodontal diagnostic aid.
Kidney function in cyclosporine-treated pediatric heart transplant recipients. (1997)

Triple immunosuppression with cyclosporine adequately protects the graft against acute rejection. It is compatible with normal glomerular function and leads to only minor tubular disturbances.
Mucin gene expression in nasal polyps (2005)

MUC6 and -7 were not expressed in sphenoid sinus mucosa, while all the studied mucin genes were expressed in nasal polyps. Expression patterns varied widely between individual polyps. The predominant epithelial mucin genes were MUC4, -5AC and -3, while MUC5B and -7 were mainly of glandular origin. MUC1, -2 and -6 were weakly expressed. The major alteration in gene expression in nasal polyps was found in the submucosal glands. MUC4 and -5AC represent a major component of both submucosal glands and epithelial cells in nasal polyps.
Thermal demagnetization analysis of CoPt magnetic recording medium by magneto-optical recording test (2001)

The thermal demagnetization process of granular CoPt perpendicular magnetic recording medium was studied by a magneto-optical recording test. Signals from recorded magnetic domains decreased by continuous laser irradiation at relatively high power. This phenomenon was caused by an acceleration of the thermal decay of written domains, which might become a crucial issue for the design of a thermally-assisted magnetic recording system. A new simple model was proposed for the analysis of the thermal degradation of this experiment. This model was in good agreement with the experimental results. According to this model, an enhancement of areal density by employing the thermally-assisted recording was roughly estimated. For the case of the examined samples, the enhancement of the areal density was about two. Possible ways to avoid the acceleration were also discussed using this model.
Chiroptical Properties of 1-Azabicyclo[3.1.0]hexane in the Vacuum-UV and IR Regions (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTChiroptical Properties of 1-Azabicyclo[3.1.0]hexane in the Vacuum-UV and IR RegionsA. Rauk, D. Yang, D. Tsankov, H. Wieser, Yu. Koltypin, A. Gedanken, and G. V. ShustovCite this: J. Am. Chem. Soc. 1995, 117, 14, 4160–4166Publication Date (Print):April 1, 1995Publication History Published online1 May 2002Published inissue 1 April 1995https://pubs.acs.org/doi/10.1021/ja00119a033https://doi.org/10.1021/ja00119a033research-articleACS PublicationsRequest reuse permissionsArticle Views75Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Early-onset autoimmunity associated with SOCS1 haploinsufficiency (2020)

Autoimmunity can occur when a checkpoint of self-tolerance fails. The study of familial autoimmune diseases can reveal pathophysiological mechanisms involved in more common autoimmune diseases. Here, by whole-exome/genome sequencing we identify heterozygous, autosomal-dominant, germline loss-of-function mutations in the SOCS1 gene in ten patients from five unrelated families with early onset autoimmune manifestations. The intracellular protein SOCS1 is known to downregulate cytokine signaling by inhibiting the JAK-STAT pathway. Accordingly, patient-derived lymphocytes exhibit increased STAT activation in vitro in response to interferon-γ, IL-2 and IL-4 that is reverted by the JAK1/JAK2 inhibitor ruxolitinib. This effect is associated with a series of in vitro and in vivo immune abnormalities consistent with lymphocyte hyperactivity. Hence, SOCS1 haploinsufficiency causes a dominantly inherited predisposition to early onset autoimmune diseases related to cytokine hypersensitivity of immune cells.
3D color contoning (2017)

We introduce a novel color reproduction method for 3D printing. In contrast to currently used halftoning techniques that use surface color mixing, our technique mixes colors inside the printed volume. This mitigates the variety of artifacts associated with color halftoning.
Lubricant Dynamics in the Sub-Nanometer Clearance Regime (2007)

This paper reviews the present state of understanding of lubricant-slider interactions in a rigid disk drive. As slider flying heights are rapidly approaching the intrinsic limit of a disk topography (1-3 nm), it has become apparent that disk-slider clearance of less than a nanometer can be achieved, at least on a laboratory setup. We will discuss the implication of such low spacing on the lubricant film behavior, and provide general physical arguments that attempt to highlight lubricant attributes that are relevant under those clearance conditions.
[Double hemorrhagic complication of endo-urologic drainage in single kidney]. (1999)

Hemorrhage is the most worrisome complication of percutaneous renal procedures, and usually occurs early in the postoperative period. The incidence of severe arterial injury is 1 to 2%. We report a patient who had 2 bleeding episodes on a solitary kidney. The first, which occurred early after the procedure, was due to an arteriocaliceal fistula treated by coil embolization. The second bleeding episode occurred two weeks later, and was caused by erosion of a lumbar artery; it was embolized by microparticles. To our knowledge, this is the first report of the imaging findings. In summary, when bleeding occurs after endourologic procedures, renal as well as extrarenal parietal causes should be investigated.
An Evaluation of Edge TPU Accelerators for Convolutional Neural Networks (2021)

Edge TPUs are a domain of accelerators for low-power, edge devices and are widely used in various Google products such as Coral and Pixel devices. In this paper, we first discuss the major microarchitectural details of Edge TPUs. Then, we extensively evaluate three classes of Edge TPUs, covering different computing ecosystems, that are either currently deployed in Google products or are the product pipeline, across 423K unique convolutional neural networks. Building upon this extensive study, we discuss critical and interpretable microarchitectural insights about the studied classes of Edge TPUs. Mainly, we discuss how Edge TPU accelerators perform across convolutional neural networks with different structures. Finally, we present our ongoing efforts in developing high-accuracy learned machine learning models to estimate the major performance metrics of accelerators such as latency and energy consumption. These learned models enable significantly faster (in the order of milliseconds) evaluations of accelerators as an alternative to time-consuming cycle-accurate simulators and establish an exciting opportunity for rapid hard-ware/software co-design.
All-optical silicon modulators based on carrier injection by two-photon absorption (2006)

This paper presents a theoretical analysis of a silicon all-optical modulator based on free-carrier injection by two-photon absorption (TPA) in a highly light-confining structure. In spite of the weak optoelectronic properties of silicon, strong light confinement allows high modulation depths in very compact devices requiring low-energy pump pulses. This analysis is applied to 1-5 mum radius silicon ring resonators with the pump pulse coupled on-chip and including in the model the scattering loss due to sidewall roughness originating from the fabrication process. The calculations show that using this scheme, modulation depths greater than 80% can be achieved, with no more than 3 pJ of pump pulse energy, at speeds on the order of 10 GHz
Findings of the WMT 2017 Biomedical Translation Shared Task (2017)

Antonio Jimeno Yepes, Aurélie Névéol, Mariana Neves, Karin Verspoor, Ondřej Bojar, Arthur Boyer, Cristian Grozea, Barry Haddow, Madeleine Kittner, Yvonne Lichtblau, Pavel Pecina, Roland Roller, Rudolf Rosa, Amy Siu, Philippe Thomas, Saskia Trescher. Proceedings of the Second Conference on Machine Translation. 2017.
Portable Imaging Polarimeter and Imaging Experiments (1999)

Polarimetry is the method of recording the state of polarization of light. Imaging polarimetry extends this method to recording the spatially resolved state of polarization within a scene. Imaging-polarimetry data have the potential to improve the detection of manmade objects in natural backgrounds. We have constructed a midwave infrared complete imaging polarimeter consisting of a fixed wire-grid polarizer and rotating form-birefringent retarder. The retardance and the orientation angles of the retarder were optimized to minimize the sensitivity of the instrument to noise in the measurements. The optimal retardance was found to be 132{degree} rather than the typical 90{degree}. The complete imaging polarimeter utilized a liquid-nitrogen cooled PtSi camera. The fixed wire-grid polarizer was located at the cold stop inside the camera dewar. The complete imaging polarimeter was operated in the 4.42-5 {micro}m spectral range. A series of imaging experiments was performed using as targets a surface of water, an automobile, and an aircraft. Further analysis of the polarization measurements revealed that in all three cases the magnitude of circular polarization was comparable to the noise in the calculated Stokes-vector components.
ChemInform Abstract: Nonbasic, Room Temperature, Palladium‐Catalyzed Coupling of Aryl and Alkenyl Iodides with Boronic Acids Mediated by Copper(I) Thiophene‐2‐carboxylate (CuTC). (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Does e-learning service quality influence e-learning student satisfaction and loyalty? Evidence from Vietnam (2019)

Prior studies on e-learning service quality were conducted mainly in developed countries; however, little effort has been made in emerging countries. This study examines the relationships among e-learning service quality attributes, overall e-learning service quality, e-learning student satisfaction, and e-learning student loyalty in the context of Vietnam, an emerging country. Survey data collected from 1232 college students were analyzed by means of exploratory factor analysis, confirmatory factor analysis, and structural equation modeling using SPSS 25 and SmartPLS 3.0. The results indicated that e-learning service quality was a second-order construct comprising of three factors, namely, e-learning system quality, e-learning instructor and course materials quality, and e-learning administrative and support service quality. The e-learning system quality was the most important dimension of overall e-learning service quality, followed by e-learning instructor and course materials quality, and e-learning administrative and support service quality. In addition, the overall e-learning service quality was positively related to e-learning student satisfaction, which in turn positively influences e-learning student loyalty. Also, overall e-learning service quality has a direct effect on e-learning student loyalty. Implications for colleges and universities are discussed.
Elevated Serum Cytokines Are Associated with Cytomegalovirus Infection and Disease in Bone Marrow Transplant Recipients (1999)

To assess the relationship between serum cytokines and cytomegalovirus (CMV) reactivation, 75 allogeneic bone marrow transplant patients underwent weekly measurements of interleukin (IL)-6, IL-8, and tumor necrosis factor (TNF)-alpha, CMV blood cultures, and antigenemia tests. Of the patients, 44 (58.7%) developed CMV infection, and 19 (25.3%) developed clinical CMV disease. The mean maximum levels of all three cytokines were significantly increased in patients with CMV infection compared with levels in those without. Maximum levels of IL-6 were significantly higher in patients with active CMV disease than in those who did not develop CMV disease (281.2+/-85.5 vs. 95.7+/-15.0 pg/mL; P=.034). Levels of IL-8 and TNF-alpha were also elevated in patients who developed active disease. In a multivariate logistic regression model, IL-6 levels were independently associated with CMV disease (odds ratio=1.70 per 100-pg/mL increase in IL-6; P=.009). Cytokines may play an important role in the pathogenesis of CMV after bone marrow transplantation and may be a useful predictor for CMV.
Supplementary Figure Legends from GSK-3β Governs Inflammation-Induced NFATc2 Signaling Hubs to Promote Pancreatic Cancer Progression (2023)

&lt;p&gt;Supplementary Figure Legends&lt;/p&gt;
Efficient Data Representation by Selecting Prototypes with Importance\n Weights (2017)

Prototypical examples that best summarizes and compactly represents an\nunderlying complex data distribution communicate meaningful insights to humans\nin domains where simple explanations are hard to extract. In this paper we\npresent algorithms with strong theoretical guarantees to mine these data sets\nand select prototypes a.k.a. representatives that optimally describes them. Our\nwork notably generalizes the recent work by Kim et al. (2016) where in addition\nto selecting prototypes, we also associate non-negative weights which are\nindicative of their importance. This extension provides a single coherent\nframework under which both prototypes and criticisms (i.e. outliers) can be\nfound. Furthermore, our framework works for any symmetric positive definite\nkernel thus addressing one of the key open questions laid out in Kim et al.\n(2016). By establishing that our objective function enjoys a key property of\nthat of weak submodularity, we present a fast ProtoDash algorithm and also\nderive approximation guarantees for the same. We demonstrate the efficacy of\nour method on diverse domains such as retail, digit recognition (MNIST) and on\npublicly available 40 health questionnaires obtained from the Center for\nDisease Control (CDC) website maintained by the US Dept. of Health. We validate\nthe results quantitatively as well as qualitatively based on expert feedback\nand recently published scientific studies on public health, thus showcasing the\npower of our technique in providing actionability (for retail), utility (for\nMNIST) and insight (on CDC datasets) which arguably are the hallmarks of an\neffective data mining method.\n
Basic study for the application of Cu supported ZnS and ZnO photocatalysts for the CO[sub 2] conversion into alcohol (2013)

Transformation of CO2 into alcohol by using photocatalysts is one of the “green” methods to solve the environmental problem. In this study, to increase the activity, condition of Cu co-catalysts onto the substrate (Zn photocatalysts) were precisely controlled by obeying to relationship between the surface potential of substrate and the condition of metal complexes in solution by applying the metal complexes calculation using critical stability constants. By obeying to calculation results, Cu metal complexes with positively charged species, [(Cu2+)(MEA)2] and [(Cu2+)(MEA)3] and/or negatively charged species, [(Cu2+)(OH−)(cit3−)] monomer and dimmer, were stably synthesized. Absorption amount of Cu species was successfully controlled by using these solutions since surface potential of ZnO was negative. When the concentration of Cu in the solution was same, the difference of adsorption amount led the difference of the number of nuclear site of Cu particles. As a result, the size of co-catalysts in the case of MEA became smaller.
Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in theARXhomeobox gene (2016)

The Aristaless-related homeobox (ARX) gene encodes a paired-type homeodomain transcription factor with critical roles in embryonic development. Mutations in ARX give rise to intellectual disability (ID), epilepsy and brain malformation syndromes. To capture the genetics and molecular disruptions that underpin the ARX-associated clinical phenotypes, we undertook a transcriptome wide RNASeq approach to analyse developing (12.5 dpc) telencephalon of mice modelling two recurrent polyalanine expansion mutations with different phenotypic severities in the ARX gene. Here we report 238 genes significantly deregulated (Log2FC > +/-1.1, P-value <0.05) when both mutations are compared to wild-type (WT) animals. When each mutation is considered separately, a greater number of genes were deregulated in the severe PA1 mice (825) than in the PA2 animals (78). Analysing genes deregulated in either or both mutant strains, we identified 12% as implicated in ID, epilepsy and autism (99/858), with ∼5% of them as putative or known direct targets of ARX transcriptional regulation. We propose a core pathway of transcription regulators, including Hdac4, involved in chromatin condensation and transcriptional repression, and one of its targets, the transcription factor Twist1, as potential drivers of the ID and infantile spasms in patients with ARX polyalanine expansion mutations. We predict that the subsequent disturbance to this pathway is a consequence of ARX protein reduction with a broader and more significant level of disruption in the PA1 in comparison to the PA2 mice. Identifying early triggers of ARX-associated phenotypes contributes to our understanding of particular clusters/pathways underpinning comorbid phenotypes that are shared by many neurodevelopmental disorders.
Development and Validation of a Multidomain Surgical Complication Classification System for Adult Spinal Deformity (2020)

The ISSG-AO Multi-Domain Spinal Deformity Complication Classification System for Adult Spinal Deformity demonstrated good accuracy and repeatability among both surgeons and research coordinators in capturing complications in adult spinal deformity surgery. The ISSG-AO system may be applied to help better understand the impact of complications on outcomes and costs in adult spinal deformity surgery.Level of Evidence: 5.
Acetone as biomarker for ketosis buildup capability - a study in healthy individuals under combined high fat and starvation diets (2015)

A statistically significant effect of Phase 2 (Day 6) diet was found on FK of Day 7, as indicated by repeated analysis of variance (ANOVA), F(2,20) = 6.73, p < 0.0058. Using a Fisher LDS pair-wise comparison, higher significant levels of acetone buildup were found for diets with 79% fat content and 90% fat content vs. 29% fat content (with p = 0.00159**, and 0.04435**, respectively), with no significant difference between diets with 79% fat content and 90% fat content. In addition, independent of the diet, a significantly higher ketone buildup capability of subjects with higher resting energy expenditure (R(2) = 0.92), and lower body mass index (R(2) = 0.71) was observed during FK.
Data from <i>EML4-ALK</i> Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; The &lt;i&gt;EML4-ALK&lt;/i&gt; fusion gene has been detected in ∼7% of Japanese non-small cell lung cancers (NSCLC). We determined the frequency of &lt;i&gt;EML4-ALK&lt;/i&gt; in Caucasian NSCLC and in NSCLC cell lines. We also determined whether TAE684, a specific ALK kinase inhibitor, would inhibit the growth of &lt;i&gt;EML4-ALK&lt;/i&gt;-containing cell lines &lt;i&gt;in vitro&lt;/i&gt; and &lt;i&gt;in vivo&lt;/i&gt;.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; We screened 305 primary NSCLC [both U.S. (&lt;i&gt;n&lt;/i&gt; = 138) and Korean (&lt;i&gt;n&lt;/i&gt; = 167) patients] and 83 NSCLC cell lines using reverse transcription-PCR and by exon array analyses. We evaluated the efficacy of TAE684 against NSCLC cell lines &lt;i&gt;in vitro&lt;/i&gt; and &lt;i&gt;in vivo&lt;/i&gt;.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; We detected four different variants, including two novel variants, of &lt;i&gt;EML4-ALK&lt;/i&gt; using reverse transcription-PCR in 8 of 305 tumors (3%) and 3 of 83 (3.6%) NSCLC cell lines. All &lt;i&gt;EML4-ALK&lt;/i&gt;-containing tumors and cell lines were adenocarcinomas. &lt;i&gt;EML4-ALK&lt;/i&gt; was detected more frequently in NSCLC patients who were never or light (&lt;10 pack-years) cigarette smokers compared with current/former smokers (6% versus 1%; &lt;i&gt;P&lt;/i&gt; = 0.049). TAE684 inhibited the growth of one of three (H3122) &lt;i&gt;EML4-ALK&lt;/i&gt;-containing cell lines &lt;i&gt;in vitro&lt;/i&gt; and &lt;i&gt;in vivo&lt;/i&gt;, inhibited Akt phosphorylation, and caused apoptosis. In another &lt;i&gt;EML4-ALK&lt;/i&gt; cell line, DFCI032, TAE684 was ineffective due to coactivation of epidermal growth factor receptor and ERBB2. The combination of TAE684 and CL-387,785 (epidermal growth factor receptor/ERBB2 kinase inhibitor) inhibited growth and Akt phosphorylation and led to apoptosis in the DFCI032 cell line.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt;&lt;i&gt;EML4-ALK&lt;/i&gt; is found in the minority of NSCLC. ALK kinase inhibitors alone or in combination may nevertheless be clinically effective treatments for NSCLC patients whose tumors contain &lt;i&gt;EML4-ALK&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;