gebhart/patrepeval huggingface dataset:
Donneurs en arrêt cardiaque : une source possible de greffons pulmonaires (2001)

La transplantation pulmonaire reste une technique experimentale. La survie a 5 ans chez les adultes greffes est de 45 a 50 %, et les chiffres sont encore moins bons pour les enfants. Parmi les problemes cruciaux, il y a le manque d'organes disponibles, ainsi que leur etat de conservation. Les moyens d'y faire face sont la transplantation d'un seul poumon, ou d'un poumon donne par un membre de la famille. L'experience de greffons preleves apres arret des battements cardiaques relatee par Steen et al. devrait donc susciter un vif interet, surtout dans les pays ou les criteres de mort cerebrale ne sont pas reconnus. La procedure comporte un refroidissement des poumons, mis en route le plus tot possible apres l'arret cardiaque, imperatif qui doit cependant tenir compte du besoin qu'ont les proches de voir la personne decedee. Steen et al. ont d'abord effectue un sondage d'opinion aupres de suedois, y compris des medecins, infirmieres, ecclesiastiques et juges. Un refroidissement opere discretement sur place paraissait ethiquement acceptable. Apres avoir mis au point la technique chez l'animal, ils ont effectue une premiere greffe chez l'homme. Une heure apres le deces du donneur, l'autorisation des proches etant obtenue, un refroidissement intrapleural a ete mis en route. Les tubulures etaient dissimulees et les membres de la famille ont pu s'isoler durant le temps qu'ils souhaitaient aupres de la personne decedee. Trois heures plus tard, le bloc cœur- poumon a ete excise et la fonction pulmonaire a ete etudiee ex vivo. En l'absence de contre-indications infectieuses ou fonctionnelles, le poumon droit a ete transplante chez une femme de 54 ans souffrant d'une bronchopneumopathie ob-structive chronique. Ce poumon a, des les 5 premieres minutes apres reperfusion et ventilation, retrouve de bonnes performances ventilatoires, performances qui se sont maintenues pendant les 5 mois de suivi postgreffe. Les auteurs concluent que toutes les personnes mourant d'une pathologie cardiaque ou cerebro-vasculaire (ce qui represente la moitie des deces en Suede) pourraient devenir des donneurs potentiels de poumon, une fois tous les centres entraines a ce type de prelevement.Steen S., et al. 2001. Transplantation of lungs from a non-heart-beating donor. Lancet 357 : 825-829.
Depolarization characteristics of ferroelectric Pb(Zr0.4Ti0.6)O3 and SrBi2Ta2O9 thin films (1995)

Abstract We evaluated depolarization characteristics of ferroelectric sol-gel Pb(Zr0.4Ti0.6)O3 and MOD (Metallo-Organic-Decomposition) Bi-layered SrBi2Ta2O9 thin-film capacitors derived by spin-on techniques with Pt electrodes. The evaluations were carried out for the extended experimental conditions, e. g., pulse height, pulse width, temperature, excess lead. Consequently, we found that the depolarization characteristics depended strongly on the capacitance of load capacitor. The newly obtained hysteresis loop during the pulse response indicates that sufficient field with opposite direction was generated on the ferroelectric capacitor at the moment the read pulse becomes zero. We experimentally found that the mechanism of depolarization is based on depoling (or partial switching) by an opposite-direction field arisen from accumulated switching charge on a load capacitor. This mechanism can be easily extended to the internal depolarization field due to the interfacial linear capacitor between the ferroelectric region and electrode.
Methods for part/device characterization and chassis engineering (2011)

Synthetic biology encompasses a variety of different approaches, methodologies and disciplines, and many different definitions exist. This Volume of Methods in Enzymology has been split into 2 Parts and covers topics such as Measuring and Engineering Central Dogma Processes, Mathematical and Computational Methods and Next-Generation DNA Assembly and Manipulation. * Encompasses a variety of different approaches, methodologies and disciplines* Split into 2 parts and covers topics such as measuring and engineering central dogma processes, mathematical and computational methods and next-generation DNA assembly and manipulation
Disruption of nuclear envelope integrity as a possible initiating event in tauopathies (2022)

The microtubule-associated protein tau is an abundant component of neurons of the central nervous system. In Alzheimer's disease and other neurodegenerative tauopathies, tau is found hyperphosphorylated and aggregated in neurofibrillary tangles. To obtain a better understanding of the cellular perturbations that initiate tau pathogenesis, we performed a CRISPR-Cas9 screen for genetic modifiers that enhance tau aggregation. This initial screen yielded three genes, BANF1, ANKLE2, and PPP2CA, whose inactivation promotes the accumulation of tau in a phosphorylated and insoluble form. In a complementary screen, we identified three additional genes, LEMD2, LEMD3, and CHMP7, that, when overexpressed, provide protection against tau aggregation. The proteins encoded by the identified genes are mechanistically linked and recognized for their roles in the maintenance and repair of the nuclear envelope. These results implicate the disruption of nuclear envelope integrity as a possible initiating event in tauopathies and reveal targets for therapeutic intervention.
MMSE whitening and subspace whitening (2003)

This correspondence develops a linear whitening transformation that minimizes the mean-squared error (MSE) between the original and whitened data, i.e.,one that results in a white output that is as close as possible to the input, in an MSE sense. When the covariance matrix of the data is not invertible, the whitening transformation is designed to optimally whiten the data on a subspace in which it is contained. The optimal whitening transformation is developed both for the case of finite-length data vectors and infinite-length signals.
The Infrared Spectra of the Complexes of Iron(II), Cobalt(II) and Nickel(II) with Biacetyldihydrazone (1960)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Infrared Spectra of the Complexes of Iron(II), Cobalt(II) and Nickel(II) with BiacetyldihydrazoneR. Carl Stoufer and Daryle H. BuschCite this: J. Am. Chem. Soc. 1960, 82, 14, 3491–3495Publication Date (Print):July 1, 1960Publication History Published online1 May 2002Published inissue 1 July 1960https://pubs.acs.org/doi/10.1021/ja01499a002https://doi.org/10.1021/ja01499a002research-articleACS PublicationsRequest reuse permissionsArticle Views414Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
What doctors and patients think about false-negative sentinel lymph nodes in vulvar cancer (2001)

The sentinel lymph node procedure is a relatively new, minimally-invasive method for the assessment of nodal status in malignancies such as breast cancer, cutaneous melanoma and vulvar cancer. Although highly accurate, this new method is inevitably associated with a certain false-negative rate, possibly leading to worse survival in a small subset of patients. The clinical implementation of the sentinel lymph node procedure is therefore a matter of ongoing debate, especially among doctors. The aim of this study was to assess opinions on the acceptable false-negative rate of the sentinel lymph node procedure in patients with vulvar cancer, who in the past had undergone standard routine radical vulvectomy and complete inguinofemoral lymphadenectomy (and frequently experienced complications), and in gynecologists treating patients with vulvar cancer. Structured questionnaires were sent to both patients and gynecologists. The patients had been treated for vulvar cancer between 1985 and 1993, and were all in complete remission with a median follow-up of 118 months (range: 76-185). Questions to the patients dealt with experienced side-effects of the standard treatment and opinion on the acceptable false-negative rate of the sentinel lymph node procedure. The response rate among patients was 91% (106/117). Forty per cent of the patients experienced one or more infections in the legs (cellulitis) and 49% of the patients still experience either severe pain and/or severe lymphedema in the legs. Sixty-six per cent of the patients preferred complete inguinofemoral lymphadenectomy in preference to a 5% false-negative rate of the sentinel lymph node procedure of 5%. Their preference was not related to age or the side-effects they had experienced. The response rate among gynecologists was 80% (80/100), of whom 60% were willing to accept a 5-20% false-negative rate of the sentinel lymph node procedure. While gynecologists may consider the sentinel lymph node procedure to be a promising diagnostic tool, the majority of vulvar cancer patients, who have undergone complete inguinofemoral lymphadenectomy in the past and have frequently experienced complications, would not advise introduction of this technique because they do not want to take any risk of missing a lymph node metastasis.
Simulation of Fluid-Structure-Interaction on Tidal Current Turbines Based on Coupled Multibody and CFD Methods (2013)

Within this paper, a method for simulation of fluid-structure-interaction (FSI) on tidal current turbines is shown. This method is based on coupled multibody and CFD methods, leading to a code that will be able to simulate the FSI on a full tidal current turbine in an adequate timescale. Besides the method and its implementation, a basic verification case is defined and compared to reference results.
RSVP-TE Signaling Extensions in Support of Flexi-Grid Dense Wavelength Division Multiplexing (DWDM) Networks (2016)

This memo describes the extensions to the Resource Reservation
Protocol - Traffic Engineering (RSVP-TE) signaling protocol to support
Label Switched Paths (LSPs) in a GMPLS-controlled network that
includes devices using the flexible optical grid.
A 2.5-dB Insertion Loss, DC-60 GHz CMOS SPDT Switch in 45-nm SOI (2011)

This paper presents a single-pole double-throw (SPDT), transmit/receive (T/R) switch operating from DC to 60 GHz. The SPDT switch is based on a series-shunt circuit with broadband input and output matching circuits and is implemented in a partially-depleted, 45-nm silicon-on-insulator (SOI) process. A buried oxide (BOX) layer is demonstrated to minimize substrate coupling. The switch exhibits a measured insertion loss of less than 1.7 dB at 45 GHz and less than 2.5 dB at 60 GHz with an isolation of greater than 25 dB at 45 GHz. To our knowledge, this is the lowest insertion loss demonstrated for an SPDT switch at 60 GHz in a CMOS process. With a control voltage of 1.2 V, the measured P <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1dB</sub> and IIP3 are 7.1 dBm and 18.2 dBm, respectively. The active chip area is 0.18×0.22 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> .
A New Frequency Partitioning and Allocation of Subcarriers for Fractional Frequency Reuse in Mobile Communication Systems (2008)

Some OFDMA-based wireless commuication systems, e. g., Wireless Broadband Internet (WiBro) or Worldwide interoperability for Microwave Access (WiMAX), support frequency reuse of 1 to maximize spectral efficiency. One of the efficient methods to reduce co-channel interference (CCI) caused by frequency reuse is fractional frequency reuse (FFR). In this paper, we propose and validate a novel frequency partitioning method and subcarrier assignment mechanism to improve system and individual capacity of mobile systems using FFR.
Large area solar cells for future space power systems (2003)

Solar cells based on GaAs are required in order to reach the efficiencies required by space applications. It is shown that subject to certain boundary conditions the efficiency of GaAs/Ge cells can reach 24% when the dual junction configuration is used or approximately 19.5% if the Ge substrate is passive. The electrooptical properties of these cells are reviewed, and prospects for achieving these efficiency goals are examined. Cell construction, cell performance modeling, and experimental performance data are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Porous three-dimensional graphene foam/Prussian blue composite for efficient removal of radioactive 137Cs (2015)

In this study, a simple one-step hydrothermal reaction is developed to prepare composite based on Prussian blue (PB)/reduced graphene oxide foam (RGOF) for efficient removal of radioactive cesium ((137)Cs) from contaminated water. Scanning electron microscopy and transmission electron microscopy show that cubic PB nanoparticles are decorated on the RGO surface. Owing to the combined benefits of RGOF and PB, the composite shows excellent removal efficiency (99.5%) of (137)Cs from the contaminated water. The maximum adsorption capacity is calculated to be 18.67 mg/g. An adsorption isotherm fit-well the Langmuir model with a linear regression correlation value of 0.97. This type of composite is believed to hold great promise for the clean-up of (137)Cs from contaminated water around nuclear plants and/or after nuclear accidents.
Direct Waste Heat Utilization From Liquid-Cooled Supercomputers (2010)

Chip microscale liquid-cooling reduces conductive and convective resistance thereby improving the efficiency of datacenters by allowing coolant temperatures above the free cooling limit in all climates. This eliminates the need for chillers and allows the thermal energy to be re-used in cold climates. Replacing the combustion processes for secondary users with recycled heat from the datacenter effectively eliminates carbon dioxide emission during the winter season and reduces operating cost throughout the year. The energy balance of emission-reduced datacenters is compared with a classical air cooled datacenter, a datacenter with free cooling in a cold climate zone, and a datacenter with chiller-mediated energy re-use. Hot water cooled datacenters reduce the effective energy cost by almost a factor of two compared to a current datacenter and reduce the carbon footprint by an even larger factor. Our energy re-use concept has been demonstrated in terms of cost and energy savings in a 60°C liquid cooled supercomputer. Additional alternative energy re-use schemes in hot climates for desalination and adsorption cooling allow close to full use of datacenter heat in all climates and all seasons. Output temperatures for these applications compared to space heating need to be 10–20°C higher which becomes possible through hotspot adapted cooling that eliminates mixing of fluids with different temperatures. In addition, interlayer cooled chip stacks allow double sided hotspot optimized cooling even closer to the heat source with low flow rates and low pumping power. This improves the large efficiency gain that becomes possible through 3D chip stacking.
Infusing Learned Priors into Model-Based Multispectral Imaging (2019)

We introduce a new algorithm for regularized reconstruction of multispectral (MS) images from noisy linear measurements. Unlike traditional approaches, the proposed algorithm regularizes the recovery problem by using a prior specified \emph{only} through a learned denoising function. More specifically, we propose a new accelerated gradient method (AGM) variant of regularization by denoising (RED) for model-based MS image reconstruction. The key ingredient of our approach is the three-dimensional (3D) deep neural net (DNN) denoiser that can fully leverage spationspectral correlations within MS images. Our results suggest the generalizability of our MS-RED algorithm, where a single trained DNN can be used to solve several different MS imaging problems.
Nanocomposites: Conjugated Polyelectrolyte/Graphene Hetero‐Bilayer Nanocomposites Exhibit Temperature Switchable Type of Conductivity (Adv. Electron. Mater. 2/2017) (2017)

V. V. Brus et al. report that the majority charge carriers in CPE-PyrBIm4/graphene heterobilayers can be dynamically changed from electrons to holes, and vice versa, within a temperature range of 60 °C. Doping mechanisms under consideration include charge transfer from electron-rich structural units in the CPE-PyrBIm4 backbone and/or field-effect doping due to interfacial electrostatic effects from adjacent ionic functionalities, as described in article number 1600515.
Yeast Reveal a “Druggable” Rsp5/Nedd4 Network that Ameliorates α-Synuclein Toxicity in Neurons (2013)

α-Synuclein (α-syn) is a small lipid-binding protein implicated in several neurodegenerative diseases, including Parkinson's disease, whose pathobiology is conserved from yeast to man. There are no therapies targeting these underlying cellular pathologies, or indeed those of any major neurodegenerative disease. Using unbiased phenotypic screens as an alternative to target-based approaches, we discovered an N-aryl benzimidazole (NAB) that strongly and selectively protected diverse cell types from α-syn toxicity. Three chemical genetic screens in wild-type yeast cells established that NAB promoted endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4. These same steps were perturbed by α-syn itself. Thus, NAB identifies a druggable node in the biology of α-syn that can correct multiple aspects of its underlying pathology, including dysfunctional endosomal and endoplasmic reticulum-to-Golgi vesicle trafficking.
ESTprep: preprocessing cDNA sequence reads (2003)

The program is freely available for download from http://genome.uiowa.edu/pubsoft/software.html
Quantum x-ray imaging for medical and industrial applications (2021)

We provide an introductory overview of medical and industrial x-ray imaging applications and requirements for readers whose primary background is in quantum imaging. We discuss some opportunities for quantum X-ray imaging and related techniques such as ghost imaging to provide meaningful benefits in imaging and explain some of the key challenges that remain before practical applications can reach end users.
Ionic Liquid Technologies for Utilization in Nuclear-Based Separations (2005)

The favorable properties of Ionic Liquids (ILs) containing organic cations, such as low melting points, lack of vapor pressure, wide liquidus ranges, and tunable physical properties, make this class of liquids particularly interesting to study as potential replacements for traditional volatile organic solvents (VOCs). While nuclear separations are mostly done using non-volatile organic phases such as octanol or dodecane, the potential to use ILs as alternatives is appealing because of the unique solvent environments and solvation properties that are presented for coordination and extraction mechanism studies. Here, we show results that illustrate the application of ILs to fundamental problems surrounding nuclear separations and waste remediation.
Sensitization of kappa opioid system in the amygdala in rat model of stress-induced medication overuse headache (2018)

Background: Migraine is the most prevalent neurological disorder, and presents an enormous global burden. Frequency of headaches and the overuse of acute medications are the major risk factors that lead to the progression to chronic migraine and medication overuse headache (MOH). Stress is consistently identified as the most common trigger of migraine. Dynorphin, an endogenous opioid peptide acting preferentially at kappa opioid receptors (KORs), is a key mediator of stress responses. The dynorphin/KOR system is widely distributed in the nervous system including amygdala, and has recently emerged as a novel therapeutic target for the treatment of stress-related mood disorders including anxiety, depression, drug seeking and relapse. We investigated whether the dynorphin/KOR system is involved in stress-induced cephalic allodynia in a rat model of MOH.
Micro-kinetic Generator: Modeling, Energy Conversion Optimization and Design Considerations (2014)

Abstract — This article focuses on a micro-kinetic generator, which is used in Autoquartz watches designed by the Swiss manufacturer ETA (part of the Swatch Group). This original electromechanical system, incorporating an intermediate energy storage located in a spring, is based on harnessing the energy from movement. We have built an electromechanical model using the Matlab Simulink application and proceeded with its experimental validation on various movement profiles. Our research has highlighted the existence of an optimal transfer of energy (obtained by either influencing generator design or regulating output voltage of the active rectifier connected to the generator) that helps maximize energy recovery. Finally, this paper presents the results of a system resizing study for the purpose of studying potential system productivity at other scales, and highlights the existence of an optimal set of parameters maximizing energy recovery. Fig. 1. 3D view [6] of the Autoquartz system I.
Retrospective Survey of Surgical Outcomes in Rhegmatogenous Retinal Detachments Associated With Atopic Dermatitis (1996)

Patients with atopic dermatitis may have an abnormality in the anterior retina and ciliary epithelium that predisposes to retinal detachment. Findings suggest a possible traumatic trigger and the need to perform an encircling scleral buckle procedure with widespread retinopexy initially in these patients.
Verification of Low-Density Lipoprotein Cholesterol Levels Measured by Anion-Exchange High-Performance Liquid Chromatography in Comparison with Beta Quantification Reference Measurement Procedure (2020)

AEX-HPLC is a reliable method for measuring LDL-C levels for CVD risk in daily clinical laboratory analyses.
Indigo Naturalis Suppresses Colonic Oxidative Stress and Th1/Th17 Responses of DSS-Induced Colitis in Mice (2019)

Indigo naturalis (also known as Qing-dai, or QD), a traditional Chinese medicine, has been widely used as an anticolitis regimen in the clinical practice of Chinese medicine. However, the precise mechanisms behind its efficacy remain unknown. We investigated the protective effects and associated molecular mechanisms of QD in DSS-induced colitis in mice. We found that QD administration attenuated DSS-induced colon shortening, tissue damage, and the disease activity index during the onset of colitis. Moreover, QD administration significantly suppressed colonic MPO activity and increased the activities of colonic T-SOD, CAT, and GSH-Px, as well the expression of p-AMPK and Nrf-2 in colon tissues of colitic mice. In addition, QD was capable of reducing the colonic Th1 and Th17 cell cytokines, the frequencies of Th1 and Th17 cells, and the phosphorylation of p-STAT1 and p-STAT3 in the mesenteric lymph nodes of colitic mice. An <i>in vitro</i> assay showed that QD significantly suppressed the differentiation of Th1 and Th17 cells. These findings suggest that QD has the potential to alleviate experimental colitis by suppressing colonic oxidative stress and restraining colonic Th1/Th17 responses, which are associated with activating AMPK/Nrf-2 signals and inhibiting STAT1/STAT3 signals, respectively. These findings also support QD as an effective regimen in the treatment of IBD.