gebhart/patrepeval huggingface dataset:
Facile and reversible homolysis of iron-germanium, -tin and -lead bonds by Lewis bases (1973)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFacile and reversible homolysis of iron-germanium, -tin and -lead bonds by Lewis basesTobin J. Marks and Alan R. NewmanCite this: J. Am. Chem. Soc. 1973, 95, 3, 769–773Publication Date (Print):February 1, 1973Publication History Published online1 May 2002Published inissue 1 February 1973https://pubs.acs.org/doi/10.1021/ja00784a022https://doi.org/10.1021/ja00784a022research-articleACS PublicationsRequest reuse permissionsArticle Views179Altmetric-Citations76LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Correction: Genetic Structure of Europeans: A View from the North–East (2010)

Using principal component (PC) analysis, we studied the genetic constitution of 3,112 individuals from Europe as portrayed by more than 270,000 single nucleotide polymorphisms (SNPs) genotyped with the Illumina Infinium platform. In cohorts where the sample size was .100, one hundred randomly chosen samples were used for analysis to minimize the sample size effect, resulting in a total of 1,564 samples. This analysis revealed that the genetic structure of the European population correlates closely with geography. The first two PCs highlight the genetic diversity corresponding to the northwest to southeast gradient and position the populations according to their approximate geographic origin. The resulting genetic map forms a triangular structure with a) Finland, b) the Baltic region, Poland and Western Russia, and c) Italy as its vertexes, and with d) Central-and Western Europe in its centre. Inter-and intra-population genetic differences were quantified by the inflation factor lambda (l) (ranging from 1.00 to 4.21), fixation index (F st ) (ranging from 0.000 to 0.023), and by the number of markers exhibiting significant allele frequency differences in pair-wise population comparisons. The estimated lambda was used to assess the real diminishing impact to association statistics when two distinct populations are merged directly in an analysis. When the PC analysis was confined to the 1,019 Estonian individuals (0.1% of the Estonian population), a fine structure emerged that correlated with the geography of individual counties. With at least two cohorts available from several countries, genetic substructures were investigated in Czech, Finnish, German, Estonian and Italian populations. Together with previously published data, our results allow the creation of a comprehensive European genetic map that will greatly facilitate inter-population genetic studies including genome wide association studies (GWAS).
Solution-Processable Crystalline Platinum-Acetylide Oligomers with Broadband Absorption for Photovoltaic Cells (2010)

A series of solution-processable and crystalline platinum−acetylide oligomers containing a thienyl−benzothiadiazole−thienyl core and oligothiophene alkynyl ligands are synthesized and characterized. X-ray crystallography analysis indicates a two-dimensional arrangement of oligomers through CH−π interactions in single crystals. These oligomers show two intense and broad absorption bands in the visible spectral region, with the short-wavelength absorption band being strongly dependent on the oligothiophene length. In neat films, all the oligomers form large crystalline domains of several hundred nanometers in size upon thermal treatment and exhibit space-charge limited current (SCLC) mobilities on the order of 10−5−10−4 cm2 V−1 s−1. The photovoltaic properties of these oligomers were evaluated by fabricating bulk heterojunction devices with fullerene derivatives (PC61BM and PC71BM) and some of these devices showed high-power conversion efficiencies (PCEs) of up to 3% and a peak external quantum efficiency (EQE) to 50% under AM 1.5 simulated solar illumination. The present work suggests that well-defined platinum oligomers with desirable light-absorbing and self-assembly properties have potential for solution-processed organic photovoltaics.
Image fusion in remote sensing by multi-objective deep learning (2020)

This paper presents a multi-objective deep learning method for the purpose of achieving image fusion or pansharpening in remote sensing. This method uses a Denoising Autoencoder (DA). Two terms are added to the commonly used mean squared error loss function. The first term involves first applying a fractional-order superimposed gradient to the PANchromatic (PAN) image for extracting the high frequency information, and then by considering the difference between the network output and the edge map of the PANchromatic image. The second term involves the difference between the universal image quality index of the low resolution MultiSpectral (MS) image and the network output for each spectral band. These terms allow both the spatial and spectral information to be better preserved in the fused image. Experimental results on three public domain datasets for both low resolution and full resolution cases are reported based on commonly used objective metrics. Compared to the existing methods, the results obtained indicate the developed multi-objective method generates comparable results for the low resolution scenario and superior performance for the full resolution scenario.
Inflammation, oxidative stress, and glial cell activation characterize stellate ganglia from humans with electrical storm (2017)

This work was made possible by support from NIH grants HL125730 to OAA, GM107949 to DBH, and HL084261 and OT2OD023848 to KS.
Blueprint of human thymopoiesis reveals molecular mechanisms of stage-specific TCR enhancer activation (2020)

Cell differentiation is accompanied by epigenetic changes leading to precise lineage definition and cell identity. Here we present a comprehensive resource of epigenomic data of human T cell precursors along with an integrative analysis of other hematopoietic populations. Although T cell commitment is accompanied by large scale epigenetic changes, we observed that the majority of distal regulatory elements are constitutively unmethylated throughout T cell differentiation, irrespective of their activation status. Among these, the TCRA gene enhancer (Eα) is in an open and unmethylated chromatin structure well before activation. Integrative analyses revealed that the HOXA5-9 transcription factors repress the Eα enhancer at early stages of T cell differentiation, while their decommission is required for TCRA locus activation and enforced αβ T lineage differentiation. Remarkably, the HOXA-mediated repression of Eα is paralleled by the ectopic expression of homeodomain-related oncogenes in T cell acute lymphoblastic leukemia. These results highlight an analogous enhancer repression mechanism at play in normal and cancer conditions, but imposing distinct developmental constraints.
Apoptosis is induced in both drug-sensitive and multidrug-resistant hepatoma cells by somatostatin analogue TT-232 (1999)

Clinical resistance to chemotherapeutic drugs is an important problem in the treatment of cancer; the circumvention of resistance has become one of the basic goals of cancer therapy. The most frequent form of primary liver cancer is hepatocellular carcinoma, which is essentially refractory to chemotherapy. We earlier showed that TT-232, a new somatostatin analogue developed in our laboratory, exerted a strong antiproliferative effect both in vitro and in vivo, but no growth hormone release inhibitory or antisecretory activity. Here we report that TT-232 has a pronounced antiproliferative effect on differentiated and dedifferentiated, drug-sensitive and multidrug-resistant hepatocellular carcinoma cell lines. TT-232 induces apoptosis at comparable levels in all these hepatoma variants demonstrating that the multidrug resistance of hepatomas does not correlate with a reduced susceptibility to apoptosis induction. These results clearly reveal that the machinery involved in apoptosis is functional in both drug-sensitive and resistant hepatoma variants and can be activated by the somatostatin analogue TT-232.
Beamspace Local LMMSE: An Efficient Digital Backend for mmWave Massive MIMO (2019)

We explore an all-digital architecture for a mmWave massive MIMO cellular uplink in which the number of users scales with the number of antenna elements at the base station. We consider the design of multiuser detection strategies after a spatial DFT, which concentrates the energy of each user onto a few DFT bins in “beamspace.” In this paper, we propose and investigate a local LMMSE receiver that exploits this property, using a small window in beamspace to demodulate each user. The proposed architecture is computationally efficient: the required window size depends on load factor (the number of users divided by the number of antenna elements) and does not scale with the number of elements. We also show that adaptive implementations of such local LMMSE receivers naturally extend to provide implicit channel estimation.
The effect of cell culture substrate on cell tolerance to desiccation (2003)

The biopreservation sciences have typically relied on the utilization of low temperature to suppress or arrest cellular physiological function in an attempt to extend biological time. Recently, however, several reports have detailed successful anhydrobiotic (dry-state) preservation of cellular systems through the utilization of stabilizing molecules such as trehalose. In this study we investigated the influence of cell-substrate interaction during and following desiccation on cell survival in a human fibroblast model. Cells were dried on differing culture surfaces after allowing 10 min for cell attachment. Desiccated samples (15% residual moisture) were rehydrated and then cultured on differing extracellular matrices. Cells cultured on biologically active matrices (collagen, fibronectin, and laminin) following desiccation resulted in a significant improvement (>15%) in cell survival in comparison with poly-L-lysine and plasma treated tissue culture surfaces. Further, both desiccation and subsequent culture of samples on biologically active surfaces resulted in /spl sim/30% increase in overall cell survival in comparison with standard culture. These findings indicate that cell-substrate interactions may play a substantial role in the success of anhydrobiotic preservation.
Pooled analysis of data from the TOMORROW and INPULSIS® trials of nintedanib in IPF (2016)

Background: The 52-week, Phase II TOMORROW trial and two replicate 52-week, Phase III INPULSIS® trials investigated the efficacy and safety of nintedanib 150 mg twice daily (bid) versus placebo in patients with idiopathic pulmonary fibrosis (IPF).
The semi-pinacol rearrangement of homochiral epoxyalcohols catalysed by rare earth triflates (2001)

α,β-Epoxy ketones, prepared using the polyleucine catalysed asymmetric epoxidation of enones, can be converted into α-substituted β-hydroxy ketones via carbonyl alkylation with Grignard reagents followed by ytterbium triflate catalysed semi-pinacol rearrangement of the resulting epoxyalcohols.
Metal-organic framework materials (2014)

Metal-Organic Frameworks (MOFs) are crystalline compounds consisting of rigid organic molecules held together and organized by metal ions or clusters. Special interests in these materials arise from the fact that many are highly porous and can be used for storage of small molecules, for example H2 or CO2. Consequently, the materials are ideal candidates for a wide range of applications including gas storage, separation technologies and catalysis. Potential applications include the storage of hydrogen for fuel-cell cars, and the removal and storage of carbon dioxide in sustainable technical processes. MOFs offer the inorganic chemist and materials scientist a wide range of new synthetic possibilities and open the doors to new and exciting basic research. Metal-Organic Frameworks Materials provides a solid basis for the understanding of MOFs and insights into new inorganic materials structures and properties. The volume also reflects progress that has been made in recent years, presenting a wide range of new applications including state-of-the art developments in the promising technology for alternative fuels. The comprehensive volume investigates structures, symmetry, supramolecular chemistry, surface engineering, recognition, properties, and reactions. The content from this book will be added online to the Encyclopedia of Inorganic and Bioinorganic Chemistry: http://www.wileyonlinelibrary.com/ref/eibc
Use of Wild Type or Recombinant Lactic Acid Bacteria as an Alternative Treatment for Gastrointestinal Inflammatory Diseases: A Focus on Inflammatory Bowel Diseases and Mucositis (2017)

The human gastrointestinal tract (GIT) is highly colonized by bacterial communities, which live in a symbiotic relationship with the host in normal conditions. It has been shown that a dysfunctional interaction between the intestinal microbiota and the host immune system, known as dysbiosis, is a very important factor responsible for the development of different inflammatory conditions of the GIT, such as the idiopathic inflammatory bowel diseases (IBD), a complex and multifactorial disorder of the GIT. Dysbiosis has also been implicated in the pathogenesis of other GIT inflammatory diseases such as mucositis usually caused as an adverse effect of chemotherapy. As both diseases have become a great clinical problem, many research groups have been focusing on developing new strategies for the treatment of IBD and mucositis. In this review, we show that lactic acid bacteria (LAB) have been capable in preventing and treating both disorders in animal models, suggesting they may be ready for clinical trials. In addition, we present the most current studies on the use of wild type or genetically engineered LAB strains designed to express anti-inflammatory proteins as a promising strategy in the treatment of IBD and mucositis.
Single Chain Polymeric Nanoparticles as Selective Hydrophobic Reaction Spaces in Water (2015)

A Ru(II)-based catalyst trapped within an amphiphilic, folded polymer is employed for the oxidation of secondary alcohols to their corresponding ketones using <i>t</i>BuOOH as the oxidant. Under the applied catalytic conditions, the polymer catalyst forms a compartmentalized structure with a hydrophobic interior. We selected secondary alcohols that differ in hydrophobicity, reactivity, and steric hindrance as substrates, with the aim to elucidate how this affects the rate and the end conversion of the oxidation reaction. Our investigations show that the Ru(II)-based catalyst is very efficient for oxidation reactions in water. Moreover, high selectivity toward the more hydrophobic substrate is observed, which originates from the hydrophobic interior of the compartmentalized catalyst system. This hydrophobic selectivity is also observed in the reverse reaction, the transfer hydrogenation.
Compressive color sensing using random complementary color filter array (2017)

We propose a new color imaging system based on a compressive sensing technique. Our system consists of a random complementary color filter array (CFA) for random projection and a color reconstruction method for demosaicing. Our CFA overlaps two complementary color filters and consists of six color filters: cyan (C), yellow (Y), magenta (M), C+Y, C+M, and Y+M. By arranging these six color filters randomly, our imaging system achieves pseudo random projection among red (R) /green (G) / blue (B) colors, which is the key technology of compressive sensing. Because this CFA can retain more color information than RGB CFA, the proposed color reconstruction method reduces artifacts at monochromatic edges and in high-frequency regions, and obtains better image quality. As an additional contribution, we introduce saturation consistency to suppress color artifacts in saturated areas, then achieve to 3.3 dB higher quality images than the conventional method.
From global seismotectonics to global seismic hazard (1993)

DOAJ is a unique and extensive index of diverse open access journals from around the world, driven by a growing community, committed to ensuring quality content is freely available online for everyone.
Biochemical Markers of Acute Coronary Syndromes (2000)

Abstract The acute coronary syndromes (ACSs) are a continuum of myocardial ischemia ranging from angina, indicating reversible tissue damage, through frank myocardial infarction (MI) with extensive tissue necrosis. The mortality from acute MI in the USA alone is 500 000 deaths per year. New predictors of cardiovascular events, that are easily measurable, are needed to improve diagnostic strategies for treating ACS patients. Cardiac markers, proteins released from the injured myocardium into the circulation, are useful for the diagnosis of MI according to the World Health Organization (WHO) criteria. Troponins I and T have emerged as sensitive, more cardiac‐specific clinical indicators for MI diagnosis and for risk stratification. A new generation of biochemical markers for indicating plaque rupture, platelet reactivity, and early MI offers promise for better assessment of patient risk so that clinicians may intervene to avoid adverse outcomes. Other biochemical markers, including the acute phase reactants and markers of thrombosis, may become useful for identifying a patient's location on the ACS spectrum and consequently the risk of adverse events. This article describes the spectrum of ACS current and future biomarkers that are closely linked to the progression of cardiac injury from ACS, and various applications of biochemical markers in assessment of reinfarction, reperfusion, perioperative MI, risk stratification, guiding therapeutic intervention, and infarct sizing. Finally, an assessment of the importance of rapid testing, different triage strategies for chest pain patients, and new trends to reduce the overall costs of patient hospitalization are discussed. The recommendations of the National Academy of Clinical Biochemistry for use of cardiac markers are also presented.
Germanium Gate-All-Around pFETs on SOI (2013)

The triangular Ge GAA pFET was fabricated and simulated. The hole concentration was obtained from spreading resistance profiling (SRP) and used in the simulation. Device with fin width (Wfin) of 52nm and Lg of 183nm has Ion/Ioff = 105, SS= 130mV/dec, and Ion=235 μA/um at Vd= -1V. The Dit of 2×1012 cm-2eV-1 for EOT of 5.5 nm is confirmed by charge pumping measurement on planar devices and numerical simulation of triangular FinFET. The TCAD simulation shows the leakage current through SOI is only 10-7X of channel current when dislocated Ge on SOI is completely etched and the fin is floated on nothing.
Bulk SiC Crystal Growth at Constant Growth Rate Utilizing a New Design of Resistive Furnace (2008)

In this work the problem of growth rate decaying during growth is considered. A new design and growth profiles are suggested in order to reduce deviations of growth parameters during the process of growth.
Correlations of the Boson Peak with Positron Annihilation in Series of Polycarbonate Copolymers (2001)

The low-frequency vibrations of the Boson peak are observed with inelastic neutron and Raman scattering in a homologous series of polycarbonate copolymers. In accordance with the notion that the Boson peak is predominantly an acoustic phenomenon, the Boson peak energy is found to correlate with the velocity of sound. However, a striking inverse correlation is observed between the Boson peak energy and the average size of the unoccupied volume elements (approximately 5−6 Å in diameter) evidenced by positron annihilation lifetime spectroscopy (PALS). The apparent correlation between the Boson peak energy and PALS data is discussed in terms of a relationship between the elastic modulus and the electron density heterogeneities.
Influence of Side Chain Interdigitation on Strain and Charge Mobility of Planar Indacenodithiophene Copolymers (2022)

Indacenodithiophene (IDT) copolymers are a class of conjugated polymers that have limited long-range order and high hole mobilities, which makes them promising candidates for use in deformable electronic devices. Key to their high hole mobilities is the coplanar monomer repeat units within the backbone. Poly(indacenodithiophene-benzothiadiazole) (PIDT<sub>C16</sub>-BT) and poly(indacenodithiophene-thiapyrollodione) (PIDT<sub>C16</sub>-TPD<sub>C1</sub>) are two IDT copolymers with planar backbones, but they are brittle at low molecular weight and have unsuitably high elastic moduli. Substitution of the hexadecane (C<sub>16</sub>) side chains of the IDT monomer with isocane (C<sub>20</sub>) side chains was performed to generate a new BT-containing IDT copolymer: PIDT<sub>C20</sub>-BT. Substitution of the methyl (C<sub>1</sub>) side chain on the TPD monomer for an octyl (C<sub>8</sub>) and 6-ethylundecane (C<sub>13B</sub>) afford two new TPD-containing IDT copolymers named PIDT<sub>C16</sub>-TPD<sub>C8</sub> and PIDT<sub>C16</sub>-TPD<sub>C13B</sub>, respectively. Both PIDT<sub>C16</sub>-TPD<sub>C8</sub> and PIDT<sub>C16</sub>-TPD<sub>C13B</sub> are relatively well deformable, have a low yield strain, and display significantly reduced elastic moduli. These mechanical properties manifest themselves because the lengthened side chains extending from the TPD-monomer inhibit precise intermolecular ordering. In PIDT<sub>C16</sub>-BT, PIDT<sub>C20</sub>-BT and PIDT<sub>C16</sub>-TPD<sub>C1</sub> side chain ordering can occur because the side chains are only present on the IDT subunit, but this results in brittle thin films. In contrast, PIDT<sub>C16</sub>-TPD<sub>C8</sub> and PIDT<sub>C16</sub>-TPD<sub>C13B</sub> have disordered side chains, which seems to lead to low hole mobilities. These results suggest that disrupting the interdigitation in IDT copolymers through comonomer side chain extension leads to more ductile thin films with lower elastic moduli, but decreased hole mobility because of altered local order in the respective thin films. Our work, thus, highlights the trade-off between molecular packing structure for deformable electronic materials and provides guidance for designing new conjugated polymers for stretchable electronics.
Annual review of plant biology (2002)

The 30 articles in the 2008 edition of the annual series summarize recent advances in plant biochemistry and biosynthesis, genetics, cell differentiation, acclimation, and investigation methods. Peggy Lemeux (Berkeley) responds to common concerns about consuming genetically engineered crops and foods, citing peer-reviewed literature of study results and interpretations. Other topics include algal sensory photoreceptors, plant processes regulated by proteases, mechanisms of salinity tolerance, patterning in seed plant shoots, cuticular wax formation by epidermal cells, and alkaloid biosynthesis.