gebhart/patrepeval huggingface dataset:
Study of Toner Penetration in Papers by Laser Induced Plasma Spectroscopy and Optical Profilometry (2023)

Four major toners are used in the printing industry, cyan, magenta, yellow and black (Key) for making color images on paper. Paper brands suitable for printing have thin mineral/latex coatings, and toners are applied on top of the coating in the printing process. Chemical compositions from toner to toner, as well as from coating to coating, vary according to the needs of the end user. Interactions between the toner and the coating define the final color formation of the images in printing. Hence, it is important to study characteristics and dynamics of toners on coated papers. In this paper, we have used laser-induced plasma spectroscopy (LIBS) to provide information on elemental distributions of the toner and the coating layers on three coated papers and the base paper at a sub-micrometer resolution. Ablation crater depth profiles in the three different material layers were converted into metric scale by combining elemental information from the LIBS measurements and optical profilometry. Ablation efficiencies for a toner of 150 nm/pulse, for a coating of approximately 350 nm/pulse and for a base paper of approximately 1 μm at a fluence of 0.6 J/cm2 of an ArF excimer laser were determined. Using these results, the average layer thicknesses of the toner and the coating layers were evaluated. The detailed analysis of the elemental profiles of the two cyan toners studied revealed strong accumulation of silicon and titanium compounds of the toner on the toner–air interface but also on the toner–coating interface, but to a much smaller extent. The observation reveals the significance of toner component diffusion due to substrate–machine interaction in the printing process. Such diffusion processes must have an important role in final color formation of the images in printing. The method developed provides a unique and accurate means to study toner diffusion processes in coated papers under printing conditions.
A run-time distributed cooperative approach to optimize power consumption in MPSoCs (2010)

Fine grain power optimization in MPSoCs architectures is now available. It is possible to independently adjust the local frequency/voltage of each processor. The objective of this work was to investigate a new system-level approach to reduce the MPSoC global power consumption at run-time. Our proposal aims to dynamically adjust the local frequency/voltage settings of each processor to save energy while maintaining real-time deadline guarantees. The developed algorithm is fully decentralized and requires only local information from nearest nodes. This algorithm is based on a combination of subgradient methods with “consensus” concepts as a mean to accelerate convergence. A telecom test-case was used to illustrate our approach. Simulation results showed that an optimization as close as 4% compared to pareto solution can be achieved. Depending on applied constraints, energy may reach 45% regarding a worst-case static configuration. Moreover, when dealing with different application standards, our optimization process offers gains of up to 80%.
BER Performance of Joint THP/pre-FDE (2008)

Recently, frequency-domain equalization (FDE) based on the minimum mean square error (MMSE) criterion has been attracting much attention to overcome the frequency-selective fading channel. The bit error rate (BER) performance of single- carrier (SC) transmission is significantly improved by using MMSE-FDE by obtaining the frequency-diversity gain while suppressing the inter-symbol interference (ISI). However, the residual ISI after MMSE-FDE limits the performance improvement. Recently, we have proposed a joint use of Tomlinson-Harashima precoding (THP) and FDE reception (joint THP/FDE) to suppress the residual ISI. However, joint THP/FDE requires the channel state information (CSI) at both the transmitter and receiver. In this paper, we replace FDE reception by pre-FDE and propose joint THP/pre-FDE that requires the CSI at the transmitter only, while providing almost the same BER performance as joint THP/FDE.
Pedicle screw accuracy in clinical utilization of minimally invasive navigated robot-assisted spine surgery (2019)

In the emerging field of robot-assisted spine surgery, the radiographic evaluation of pedicle screw accuracy in clinical application is an area of high interest. This study describes the pedicle screw accuracy of the first 56 consecutive cases in which navigated robotic assistance was used in a private practice clinical setting. A retrospective, Institutional Review Board-exempt review of the first 56 navigated robot-assisted spine surgery cases was performed. Pedicle screw malposition, reposition, and return to operating room (OR) rates were collected. A CT-based Gertzbein and Robbins system (GRS) was used to classify pedicle screw accuracy. In the first 56 robotic cases, 356 total pedicle screws were placed. Eight screws were placed without the robot due to surgeon discretion. Of the 348 pedicle screws inserted by navigated robotic guidance, only 2.6% (9/348) were repositioned, resulting in a 97.4% (339/348) successful screw placement rate. The average age was 64, and 48% were female. Average body mass index was 31 kg/m<sup>2</sup>. Based on the GRS CT-based grading, 97.7% (340/348) were graded A or B, 1.7% (6/348) screws were graded C, and only 0.6% (2/348) of screws were graded D. Two complications, explantation of interbody and vacuum-assisted wound closure, were reported as requiring a return to the OR, but these were not related to robotic guidance or pedicle screws. This study demonstrated a high level of accuracy (97.7%) in the first 56 cases using navigated, robot-assisted surgery based on the GRS. There were two non-screw-related complications requiring return to the operating room.
Echocardiographic and functional cardiopulmonary problems 6 months after first-time pulmonary embolism in previously healthy patients (2007)

Six months after first-time PE, 41% of previously healthy patients had either an abnormal RV on echo, an NYHA score > II or a 6MWD < 330 m. Treatment studies of PE should include these persistent cardiopulmonary problems as study endpoints.
RTT Positioning Field Performance (2010)

The performance of cellular-positioning methods is characterized in terms of availability, response time, and accuracy. This paper discusses the measured field performance of Ericsson's round-trip time (RTT) positioning method in terms of the aforementioned parameters. The results are based on more than 1200 position fixes performed in a large commercial wideband code-division multiple-access (WCDMA) network. More than 100 surveyed test points were used, these being located in indoor, urban, suburban, and rural radio environments. Overviews of the RTT positioning algorithm, the test points, the test equipment, and the measurement procedures are given first. Then, this paper presents measurement geometries (for example, in soft handover), as well as the achieved performance in each radio environment. The radial distance accuracy was found to be excellent, despite the fact that propagation conditions were difficult with many open water surfaces. A bias of less than 5 m at the 50% point of the cumulative distribution function and a 95% error just above 150 m were obtained, averaged over all radio environments.
Indirect Excitons and Trions in MoSe2/WSe2 van der Waals Heterostructures (2020)

Indirect excitons (IX) in semiconductor heterostructures are bosons, which can cool below the temperature of quantum degeneracy and can be effectively controlled by voltage and light. IX quantum Bose gases and IX devices were explored in GaAs heterostructures where an IX range of existence is limited to low temperatures due to low IX binding energies. IXs in van der Waals transition-metal dichalcogenide (TMD) heterostructures are characterized by large binding energies giving the opportunity for exploring excitonic quantum gases and for creating excitonic devices at high temperatures. TMD heterostructures also offer a new platform for studying single-exciton phenomena and few-particle complexes. In this work, we present studies of IXs in MoSe<sub>2</sub>/WSe<sub>2</sub> heterostructures and report on two IX luminescence lines whose energy splitting and temperature dependence identify them as neutral and charged IXs. The experimentally found binding energy of the indirect charged excitons, that is, indirect trions, is close to the calculated binding energy of 28 meV for negative indirect trions in TMD heterostructures [Deilmann, T.; Thygesen, K. S. <i>Nano Lett.</i> 2018, 18, 1460]. We also report on the realization of IXs with a luminescence line width reaching 4 meV at low temperatures. An enhancement of IX luminescence intensity and the narrow line width are observed in localized spots.
Obtaining real-time sub-meter accuracy using a low cost GNSS device (2016)

Autonomous vehicles require accurate position at all times in different environments at an affordable price. This accurate position can only be achieved when combining multiple positioning methods. One of these methods is presented in this paper: positioning based on a Global Navigation Satellite System (GNSS) to obtain absolute position. This solution should be at an affordable price with sub-meter position accuracy. At the University of Delft, the Netherlands, a low cost solution was developed in Matlab for open areas which is called Single Frequency Precise Point Positioning (SF-PPP). It uses a low cost receiver with single frequency, single antenna and single GNSS constellation (GPS). The receiver provides raw measurements to the SF-PPP algorithm which corrects them for different kind of errors. This method was ported to a low cost Commercial Off-The-Shelf (COTS) embedded platform in C++. The selected platform is a Raspberry Pi version 2 with a u-Blox NEO 7P GPS receiver. The corrections for the raw measurements are received from a network service via a 4G modem. The PPP method is validated with an RTK system which is cm accurate. We evaluated the PPP method in different environments and conditions, with focus on open area, but also for harsh conditions on the highway and in an urban environment to know the current limitations of the method. For the open area environment a horizontal root mean square error (RMSe) of 0.5 m on position coordinates was achieved which fulfills our target of submeter accuracy. In harsh environments we suffer from reflections (caused by multipath receptions) and poor satellite availability due to obstructions from trees and buildings which makes the accuracy varying from 0.5 m up to 3 m. Future plans to improve the results involve using more satellites from other constellations like GLONASS, using the Doppler shift to estimate the vehicle speed, using dual frequency receiver for ionosphere removal and closer integration with other low-cost sensors and vehicle model.
Gas-phase protein conformation/multimer ion formation by electrospray ion mobility-mass spectrometry: bovine insulin and ubiquitin (2016)

Ion mobility-mass spectrometry (IMMS) is a very attractive method for studies in structural biology because of the ability of rapid isolation by nearly simultaneous m/z characterization and size separation, leading to an emergence of IMMS as a complimentary biochemical tool. Earlier, we developed a method based on varying the protein concentration in solution prior to electrospray ionization (ESI) with subsequent m/z selection and dissociation of protein multimers by IMMS of cytochrome c. The focus of this work will be to correctly distinguish truly different ion conformations formed by ESI versus homomultimeric complexes with the same m/z for well-studied proteins bovine ubiquitin and insulin. These proteins were chosen due to their large difference in solution phase structures: insulin tightly bound by disulfide linkages, and ubiquitin-a protein that may adopt a range of states from compact to extended. Our preliminary results, as with cytochrome c reveal false negatives for protein oligomer formation and false positives for protein conformational states. In addition, these results will be couched in terms of the need for quantification of IMMS analysis of proteins given the total area under IMMS peaks can also distinguish conformation versus aggregation as higher order oligomers have more mass per ion.This article is part of the themed issue 'Quantitative mass spectrometry'.
Near Optimal Broadcast with Network Coding in Large Homogeneous Wireless Networks (2007)

We propose an efficient broadcast algorithm for wireless networks, based on network coding: we introduce a simple rate selection and analyze its performance (through computation of min-cut). By broadcast, we mean sending data from one source to all the other nodes in the network, and our metric for efficiency is the number of transmissions necessary to transmit one packet from the source to every destination. We address this problem, in some special cases of wireless ``homogeneous'' networks contained of the plane: wireless lattice networks, and dense unit disk networks. Our results are based on the simple principle of ``Increased Rate for Exceptional Nodes, Identical Rate for Other Nodes'' (IREN/IRON), for setting rates on the nodes (wireless links) of the network. With this rate selection, we give a value of the maximum broadcast rate of the source: our central result is a proof of the value of the min-cut for such networks. In particular, we show that for our scenarios, network coding is outperforming any method without network coding.
Mixed Micromax and hematite-based fly ash geopolymer for heavy-weight well cementing (2023)

Ordinary Portland cement (OPC) has introduced different environmental and technical issues. Researchers tried either adding new materials to cement or developing alternatives for both technical and environmental challenges. Hematite as a weighting agent is used to increase cement slurry density. Heavy particles sedimentation in cement and geopolymer slurries is a serious issue which creates heterogenous properties along the cemented section. This work presents a new class of geopolymers using both hematite and Micromax as weighting materials for high density well cementing applications. The first system used only hematite while the other system used both hematite and Micromax. The main goal behind using Micromax with hematite is to check the possibility of eliminating the sedimentation issue associated with hematite in geopolymers. Moreover, the effects of adding Micromax on different FFA geopolymer properties were also evaluated. Different mixtures of retarder, retarder intensifier and superplasticizer were introduced to increase the thickening times of the developed geopolymer systems. The results showed that adding Micromax to hematite decreased the average density variation from 12.5% to almost 3.9%. Micromax addition reduced plastic viscosity by 44.5% and fluid loss by 10.5%. Both systems had a close performance in terms of strength, elastic properties, and permeability. The thickening time was 390 min for the hematite system and 300 min for the mixed system using the proposed additives mixtures.
Promoting microbial utilization of phenolic substrates from bio-oil (2019)

The economic viability of the biorefinery concept is limited by the valorization of lignin. One possible method of lignin valorization is biological upgrading with aromatic-catabolic microbes. In conjunction, lignin monomers can be produced by fast pyrolysis and fractionation. However, biological upgrading of these lignin monomers is limited by low water solubility. Here, we address the problem of low water solubility with an emulsifier blend containing approximately 70 wt% Tween<sup>®</sup> 20 and 30 wt% Span<sup>®</sup> 80. Pseudomonas putida KT2440 grew to an optical density (OD<sub>600</sub>) of 1.0 ± 0.2 when supplied with 1.6 wt% emulsified phenolic monomer-rich product produced by fast pyrolysis of red oak using an emulsifier dose of 0.076 ± 0.002 g emulsifier blend per g of phenolic monomer-rich product. This approach partially mitigated the toxicity of the model phenolic monomer p-coumarate to the microbe, but not benzoate or vanillin. This study provides a proof of concept that processing of biomass-derived phenolics to increase aqueous availability can enhance microbial utilization.
On the asymptotic performance of the decorrelator (2003)

We derive the asymptotic signal-to-interference ratio (SIR) of the decorrelator in the large system limit, both for the case in which the number of users exceeds the spreading gain and for the case in which the number of users is less than the spreading gain. We show that, contrary to what is claimed by Tse and Hardy (see ibid., vol.45, p.641-57, Mar. 1999) and by Tse and Zeitouni (see ibid., vol.46, p.171-188, Jan. 2000) when the number of users exceeds the spreading gain and the decorrelator is defined in terms of the Moore-Penrose pseudoinverse, the SIR does not converge to zero.
DoF analysis in a two-layered heterogeneous wireless interference network (2017)

Degrees of freedom (DoF) is studied in the downlink of a heterogenous wireless network modeled as a two-layered interference network. The first layer of the interference network is the backhaul layer between macro base stations (MBs) and small cell base stations (SBs), which is modeled as a Wyner type linear network. The second layer is the transmission layer between SBs and mobile terminals (MTs), which is modeled as a linear Wyner L <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> network. The SBs are assumed to be half-duplex, thus restricting the per user degrees of freedom (puDoF) in the system to 1/2. It is established that the optimal puDoF of 1/2 can be achieved in the linear network with sufficient number of antennas using only interference avoidance schemes. For the case of higher connectivity in the transmission layer, it is shown that the optimal puDoF is achieved by sending an appropriate linear combination to the SB to zero-force interference at the intended user. These results are also extended to a more realistic hexagonal cellular model.
Resilience of transfluthrin to oxidative attack by duplicated CYP6P9 variants known to confer pyrethroid resistance in the major malaria mosquito Anopheles funestus (2023)

Resistance to common pyrethroids, such as deltamethrin and permethrin is widespread in the malaria mosquito Anopheles funestus and mainly conferred by upregulated cytochrome P450 monooxygenases (P450s). In the pyrethroid resistant laboratory strain An. funestus FUMOZ-R the duplicated genes CYP6P9a and CYP6P9b are highly upregulated and have been shown to metabolize various pyrethroids, including deltamethrin and permethrin. Here, we recombinantly expressed CYP6P9a and CYP6P9b from An. funestus using a baculovirus expression system and evaluated the interaction of the multifluorinated benzyl pyrethroid transfluthrin with these enzymes by different approaches. First, by Michaelis-Menten kinetics in a fluorescent probe assay with the model substrate 7-benzyloxymethoxy-4-trifluoromethylcoumarin (BOMFC), we showed the inhibition of BOMFC metabolism by increasing concentrations of transfluthrin. Second, we tested the metabolic capacity of recombinantly expressed CYP6P9 variants to degrade transfluthrin utilizing UPLC-MS/MS analysis and detected low depletion rates, explaining the virtual lack of resistance of strain FUMOZ-R to transfluthrin observed in previous studies. However, as both approaches suggested an interaction of CYP6P9 variants with transfluthrin, we analyzed the oxidative metabolic fate and failed to detect hydroxylated transfluthrin, but low amounts of an M-2 transfluthrin metabolite. Based on the detected metabolite we hypothesize oxidative attack of the gem-dimethyl substituted cyclopropyl moiety, resulting in the formation of an allyl cation upon ring opening. In conclusion, these findings support the resilience of transfluthrin to P450-mediated pyrethroid resistance, and thus, reinforces its employment as an important resistance-breaking pyrethroid in resistance management strategies to control the major malaria vector An. funestus.
Signals transduced by CD3epsilon, but not by surface pre-TCR complexes, are able to induce maturation of an early thymic lymphoma in vitro. (1999)

Development of immature CD4-CD8- (double-negative) thymocytes to the CD4+CD8+ (double-positive) stage is linked to productive rearrangement of the TCRbeta locus by signals transduced through the pre-TCR. However, the mechanism whereby pre-TCR signaling is initiated remains unclear, in part due to the lack of an in vitro model system amenable to both biochemical and genetic analysis. In this study, we establish the thymic lymphoma Scid.adh as such a model system. Scid.adh responds to Ab engagement of surface IL-2Ra (TAC):CD3epsilon molecules (a signaling chimera that mimics pre-TCR signaling in vivo) by undergoing changes in gene expression observed following pre-TCR activation in normal thymocytes. These changes include down-regulation of CD25, recombinase-activating gene (RAG)-1, RAG-2, and pTalpha; and the up-regulation of TCRalpha germline transcripts. We term this complete set of changes in gene expression, in vitro maturation. Interestingly, Scid.adh undergoes only a subset of these changes in gene expression following Ab engagement of the pre-TCR. Our findings make two important points. First, because TAC:CD3epsilon stimulation of Scid.adh induces physiologically relevant changes in gene expression, Scid.adh is an excellent cellular system for investigating the molecular requirements for pre-TCR signaling. Second, Ab engagement of CD3epsilon signaling domains in isolation (TAC:CD3epsilon) promotes in vitro maturation of Scid.adh, whereas engagement of CD3epsilon molecules contained within the complete pre-TCR fails to do so. Our current working hypothesis is that CD3epsilon fails to promote in vitro maturation when in the context of an Ab-engaged pre-TCR because another pre-TCR subunit(s), possibly TCRzeta, qualitatively alters the CD3epsilon signal.
ChemInform Abstract: Inhibitors of an Essential Mycobacterial Cell Wall Lipase (Rv3802c) as Tuberculosis Drug Leads. (2011)

Abstract Among the newly synthesized compounds, the N‐acetyl and the N‐formyl derivative of (V) belongs to the most potent inhibitors.
Efficient Scavenging of Fatty Acid Oxidation Products by Aminoguanidine (1997)

Lipid oxidation leads to the formation of reactive aldehydes that may play an important role in atherogenesis by altering the normal pathway of lipoprotein metabolism and by exerting toxic effects on vascular wall components. Recent studies indicate that advanced glycation end products, which form spontaneously from the reaction of reducing sugars with amino groups, may promote oxidative damage in vivo. Moreover, the pharmacological inhibitor of advanced glycation aminoguanidine has been shown to lower circulating low-density lipoprotein levels in human subjects and to inhibit certain oxidative reactions in vitro. To define more precisely the potential interaction of AG with oxidized lipids, we have studied and identified the major products that form from the reaction of AG with the oxidation products 4-hydroxynonenal and malondialdehyde. AG was found to be an efficient scavenger of alpha,beta-unsaturated aldehydes when compared to nucleophilic amino acids (Cys, Lys, His), suggesting that one of its mechanisms of action in vivo is to protect tissue constituents from the damaging effects of oxidative stress.