gebhart/patrepeval huggingface dataset:
X-ray photoelectron spectroscopy of carbon in commercial copper phthalocyanine pigments (2010)

This paper presents systematic studies of the C1s signal in the X-ray photoelectron spectra of commercial Cu-phthalocyanine (CuPc) commonly used as a major commercial cyan pigment in a variety of printing applications. Although the CuPc pigment has been widely employed for many decades, the correct interpretation of the C1s signal in non-stoichiometric CuPc pigments has not yet been agreed upon. Our work demonstrates that the composite C1s CuPc signal consists of five components: two related to principal C positions within the CuPc macrocycle, two associated with shake-up transitions accompanying the principal C positions, and one due to mostly aliphatic impurities. A detailed analysis showed that magnitude of shake-up peaks was approximately equal 10% to 12% of their principal transitions, in agreement with theoretical calculations, while the impurities C1s signal corresponded to IR measurement of the aliphatic C-H vibrations. The proposed C1s interpretation has been successfully tested for a large number of commercial CuPc pigments and provides a guideline for routine XPS analysis of the CuPc that can provide a reliable pigment quality control.
Optical Fiber Long-Period Grating with Nanoscale Coatings for Rapid Identification of Bacterial Infections (2018)

Rapid identification (&lt;1 hour) of the bacteria methicillin-resistant Staphylococcus and Histophilus somni are demonstrated using an ionic self-assembled multilayer (ISAM) film deposited on the surface of a long-period grating (LPG) optical fiber.
Does training respiratory physicians in clinical respiratory physiology and interpretation of pulmonary function tests improve core knowledge? (2017)

Lung function tests have a major role in respiratory medicine. Training in lung function tests is variable within the European Union. In this study, we have shown that an internship in a lung function tests laboratory significantly improved the technical and diagnostic skills of French respiratory trainees.
Use of Boronates in the Petasis Reaction. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access the actual ChemInform Abstract, please click on HTML or PDF.
TLRs Govern Neutrophil Activity in Aspergillosis (2004)

Polymorphonuclear neutrophils (PMNs) are essential in initiation and execution of the acute inflammatory response and subsequent resolution of fungal infection. PMNs, however, may act as double-edged swords, as the excessive release of oxidants and proteases may be responsible for injury to organs and fungal sepsis. To identify regulatory mechanisms that may balance PMN-dependent protection and immunopathology in fungal infections, the involvement of different TLR-activation pathways was evaluated on human PMNs exposed to the fungus Aspergillus fumigatus. Recognition of Aspergillus and activation of PMNs occurred through the involvement of distinct members of the TLR family, each likely activating specialized antifungal effector functions. By affecting the balance between fungicidal oxidative and nonoxidative mechanisms, pro- and anti-inflammatory cytokine production, and apoptosis vs necrosis, the different TLRs ultimately impacted on the quality of microbicidal activity and inflammatory pathology. Signaling through TLR2 promoted the fungicidal activity of PMNs through oxidative pathways involving extracellular release of gelatinases and proinflammatory cytokines while TLR4 favored the oxidative pathways through the participation of azurophil, myeloperoxidase-positive, granules and IL-10. This translated in vivo in the occurrence of different patterns of fungal clearance and inflammatory pathology. Both pathways were variably affected by signaling through TLR3, TLR5, TLR6, TLR7, TLR8, and TLR9. The ability of selected individual TLRs to restore antifungal functions in defective PMNs suggests that the coordinated outputs of activation of multiple TLRs may contribute to PMN function in aspergillosis.
Multi-Client Non-Interactive Verifiable Computation. (2015)

Abstract. Gennaro et al. (Crypto 2010) introduced the notion of noninteractive verifiable computation, which allows a computationally weak client to outsource the computation of a function f on a series of inputs x (1) ,... to a more powerful but untrusted server. Following a preprocessing phase (that is carried out only once), the client sends some representation of its current input x (i) to the server; the server returns an answer that allows the client to recover the correct result f(x (i)), accompanied by a proof of correctness that ensures the client does not accept an incorrect result. The crucial property is that the work done by the client in preparing its input and verifying the server’s proof is less than the time required for the client to compute f on its own. We extend this notion to the multi-client setting, where n computationally weak clients wish to outsource to an untrusted server the computation of a function f over a series of joint inputs (x (1) 1,..., x(1) n),... without interacting with each other. We present a construction for this setting by combining the scheme of Gennaro et al. with a primitive called proxy oblivious transfer. 1
On Multidimensional Sharpening of Uncertain Data (2010)

In this paper, we will propose a technique for multidimensional enhancement of uncertain data. In many applications, the uncertainty in the different dimensions is caused by independent factors, especially if the different dimensions have been collected from independent sources. In such cases, it is possible to enhance the quality of the data and reduce the underlying uncertainty by using multidimensional uncertainty analysis. In this paper, we will discuss techniques for uncertainty reduction of multidimensional uncertain data. We will examine the effectiveness of the approach over a variety of real and synthetic data sets.
Should we prefer inverse models in quantitative LIBS analysis? (2020)

The simple linear regression is one of the oldest statistical tools to predict a concentration from a measured signal. However, do we use the right independent and dependent variables in LIBS?
A Study of Supermaneuverable Flight Trajectories Through Motion Field Simulation of a Centrifuge Simulator (1992)

The advent of supermaneuverable flight trajectories for high performance aircraft opens up new research areas involving the human factors effects on pilots when they fly these unusual flight scenarios. There exists a need to conduct studies in motion simulators such as centrifuges to investigate how these unusual motion fields effect humans both physiologically and how they impact the ability of a pilot to perform a mission. The dynamic control of a centrifuge simulator to emulate supermaneuverable flight trajectories is studied in this paper by considering the centrifuge simulator as a 3 revolute axes robot manipulator.
Single-Trial EEG Connectivity of Default Mode Network Before and During Encoding Predicts Subsequent Memory Outcome (2020)

The successful memory process produces specific activity in the brain network. As the brain activity of the prestimulus and encoding phases has a crucial effect on subsequent memory outcomes (e.g., remembered or forgotten), previous studies have tried to predict the memory performance in this period. Conventional studies have used the spectral power or event-related potential of specific regions as the classification feature. However, as multiple brain regions work collaboratively to process memory, it could be a better option to use functional connectivity within the memory-related brain network to predict subsequent memory performance. In this study, we acquired the EEG signals while performing an associative memory task that remembers scene-word pairs. For the connectivity analysis, we estimated the cross-mutual information within the default mode network with the time-frequency spectra at the prestimulus and encoding phases. Then, we predicted the success or failure of subsequent memory outcome with the connectivity features. We found that the classifier with support vector machine achieved the highest classification accuracy of 80.83% ± 12.65% (mean ± standard deviation) using the beta (13-30 Hz) connectivity at encoding phase among the multiple frequency bands and task phases. Using the prestimulus beta connectivity, the classification accuracy of 72.45% ± 12.52% is also achieved. Among the features, the connectivity related to the dorsomedial prefrontal cortex was found to contribute to successful memory encoding. The connectivity related to the posterior cingulate cortex was found to contribute to the failure of memory encoding. The present study showed for the first time the successful prediction with high accuracy of subsequent memory outcome using single-trial functional connectivity.
The Effects of Crystallinity on the Mechanical Properties of PEEK Polymer and Graphite Fiber Reinforced PEEK (1987)

The mechanical properties of PEEK 150P polymer and APC-2 graphite/PEEK com posite were measured at different crystallinities, from 0 to 40 weight percent. For PEEK 150P the tensile, compressive, and shear properties and the fracture toughness were measured. For APC-2 the mode I and mode II fracture toughnesses and fracture energies as well as the mixed mode stress intensity factors were determined. Expressions are pre sented relating the mechanical properties to crystallinity. Finally, data are given which compare the mechanical properties of materials in which the same crystallinity was estab lished by different thermal processes.
MEDLINE as a parallel corpus: a survey to gain insight on French-, Spanish- and Portuguese-speaking authors' abstract writing practice (2020)

International audience
Engineering Microenvironment of Biodegradable Polyester Systems for Drug Stability and Release Control (2021)

Polymeric systems made of poly(lactic acid) or poly(lactic-co-glycolic acid) are widely used for long-term delivery of small and large molecules. The advantages of poly(lactic acid)/poly(lactic-co-glycolic acid) systems include biodegradability, safety and a long history of use in US FDA-approved products. However, as drugs delivered by the polymeric systems and their applications become more diverse, the significance of microenvironment change of degrading systems on long-term drug stability and release kinetics has gained renewed attention. In this review, we discuss various issues experienced with acidifying microenvironment of biodegradable polymer systems and approaches to overcome the detrimental effects of polymer degradation on drug stability and release control.
Electrochemical Techniques (2002)

Abstract Electrochemistry, in contrast to most materials characterization disciplines, contains a bifurcated methodology having applications both in materials synthesis and as a physical characterization technique. On the one hand, a variety of functional surfaces are prepared electrochemically, for example, the anodization of aluminum, electroetching of semiconductors, and electroplating of metallic films. Similarly, the electrosynthesis of bulk materials such as conducting organic polymers has taken on importance in recent years. On the other hand, electrochemistry has been demonstrated to be of use as a physical characterization technique for the quantification of conducting and semiconducting surfaces. The corrosion properties of metallic surfaces and semiconductor electronic properties are two key areas where electrochemical characterization has had a high impact. In keeping with the central analytical theme of this work, this category limits its focus to the class of electrochemical techniques specifically aimed at characterizing materials and their interfaces (as opposed to synthetic electrochemistry). In some cases, the line between materials synthesis and measurement can become hazy. The field of sensors based on chemically modified electrodes (CMEs) is a good example of this confusion. Often sensors of this type are electrosynthesized and the synthesis parameters represent an important portion of the systems characterization. Cases such as this are included in the topical coverage of these articles.
QSAR/QSPR and Proprietary Data (2006)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTQSAR/QSPR and Proprietary DataWilliam L. JorgensenView Author Information Editor-in-ChiefCite this: J. Chem. Inf. Model. 2006, 46, 3, 937Publication Date (Web):May 22, 2006Publication History Published online22 May 2006Published inissue 1 May 2006https://pubs.acs.org/doi/10.1021/ci0680079https://doi.org/10.1021/ci0680079editorialACS PublicationsCopyright © 2006 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views3678Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (8 KB) Get e-AlertscloseSUBJECTS:Bioinformatics and computational biology,Drug discovery,Metabolism,Screening assays,Structure activity relationship Get e-Alerts
Glomus Tumor of the Stomach: Depiction by Multidetector CT and Three-Dimensional Volume Rendering Imaging (2010)

Glomus tumors are uncommon tumors which can occur anywhere within the gastrointestinal tract but have been shown to occur most commonly in the gastric antrum. On CT, these tumors demonstrate hyperenhancement which may help distinguish them from other gastric masses.
ChemInform Abstract: Azaindole Derivatives with High Affinity for the Dopamine D4 Receptor: Synthesis, Ligand Binding Studies and Comparison of Molecular Electrostatic Potential Maps. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The N‐terminal amino acid of apolipoprotein D is putatively covalently bound to 3‐hydroxy‐3‐methyl hexanoic acid, a key odour compound in axillary sweat (2011)

Axillary sweat is odourless when freshly collected at the surface of human skin, but it contains non-odoriferous precursors, which can be transformed into odorous substances by bacteria. E-3-methyl-2-hexanoic acid (3M2H) is one of the key odorous substances, but there are two contradictory reports about its precursor form. One report states that 3M2H linked non-covalently to apolipoprotein D (apoD) is the precursor, while a second report states that 3M2H-Gln identified in human axillary sweat is the precursor. Recently, 3-hydroxy-3-methyl hexanoic acid (HMHA) and 3-methyl-3-sulfanylhexane-1-ol (3M3T) have also been identified and reported as characteristic components found in apocrine sweat. To better understand the formation of axillary odours and the structural relationships between these compounds and apoD, we characterized the linkage between odorous substances and apoD in human axillary secretions. ApoD was purified from human axillary secretions collected from 50 healthy female volunteers and was then digested by trypsin and analysed by MALDI-TOF mass spectrometry. A Mascot search showed that 8 peaks identified in the trypsin-digested samples correspond to the masses calculated for theoretically digested apoD sequences and the purified protein was assigned as a precursor of apoD [Homo sapiens]. One spectrum corresponded to the theoretical peak of HMHA linked covalently to the N-terminal fragment of apoD. In contrast, no spectrum corresponded to the theoretical peak of a 3M2H adduct or to an unmodified N-terminal fragment of apoD. These results indicate a possibility that HMHA binds covalently to the N-terminal amino acid of apoD in human axillary secretions.
Diagnostics of blast-furnace linings (2017)

Hatch (Canada) has developed a system for the nondestructive monitoring of the residual lining thickness in blast furnaces and eletrofurnaces. This system, which is based on an acoustic–ultrasound echo signal (AU-E), supplements the traditional thermal simulation of the furnace lining by means of built-in thermocouples or on the basis of the thermal load on the cooling units in the blast furnace. By this means, the position of cracks and anomalies may be determined, and the boundary between the coating and the refractory may be identified. The constraints and sources of error in the AU-E method are analyzed, and an improved version is outlined. The improved method takes account of the influence of the following factors on the wave propagation: high temperatures; the furnace shape and size; and the difference in acoustic resistance of different layers in a multilayer refractory lining. The AU-E method permits reliable and nondestructive monitoring of the refractory lining in smelting furnaces. The hardware and software of the AU-E system have been significantly improved, so as to obtain measurements of satisfactory accuracy. Estimates of the method’s precision are confirmed by physical measurements on inoperative blast furnaces. Examples of the utilization of this diagnostic system at various Russian and non-Russian plants are presented. Some technological measures that extend the blast-furnace run are noted. As shown in the present study, the use of several successive measurements permits the determination of the lining’s wear rate and the time remaining before major repair. The AU-E method continues to operate well at more than 70 blast furnaces around the world, including those at the Novolipetsk, Cherepovets, Nizhny Tagil, Western Siberian, and Magnitogorsk steel works, as well as at electrofurnaces producing ferroalloys, copper, and platinum.
Recruitment of Nuclear Receptor Corepressor and Coactivator to the Retinoic Acid Receptor by Retinoid Ligands (2000)

Ligand activation of retinoic acid receptors (RARs) involves coordinated changes in their interaction with coregulatory molecules. Binding of the agonist all-trans-retinoic acid to the RAR results in increased interaction with coactivator molecules as well as a decreased interaction with corepressor molecules. Thus, an all-trans-retinoic acid antagonist might function either by preventing agonist induction of such events or, additionally, by actively increasing repression via corepressor recruitment. We demonstrate that the repression of the transcriptional activity of a constitutively active RARgamma-VP-16 chimeric receptor by the inverse agonist AGN193109 requires a functional Co-R box and that binding of this ligand to RARgamma leads to an increased interaction with the corepressor N-CoR both in glutathione S-transferase pull-down and yeast two-hybrid analyses. Detection of nuclear receptor corepressor (N-CoR) association with RARgamma was greatly facilitated by inclusion of a RARE oligonucleotide in coimmunoprecipitation analyses, a result of an increase in association of the ternary complex consisting of RAR, RXR, and DNA. Similarly, this DNA-dependent increase in heterodimer formation likewise resulted in an increase in agonist-mediated recruitment efficiency of the coactivator SRC-1. Under conditions which favor ternary complex formation, a RAR neutral antagonist is distinguished from an inverse agonist with respect to corepressor recruitment as is a RAR partial agonist distinguished from an agonist with respect to coactivator recruitment. These results indicate that it is possible to design RAR ligands with distinct recruitment capabilities for coregulators, both coactivators as well as corepressors. In addition, using this recruitment assay, we show that SRC-1 and the related coactivator molecule ACTR associate with the ternary complex via utilization of different helical motifs within their conserved receptor interaction domains.
Isolation of Bioactive Compounds from Aspergillus terreus (2004)

A new metabolite, 6-(4’-hydroxy-2’-methyl phenoxy)-(-)-(3R)-mellein (1) was isolated from the ethyl acetate extract of Aspergillus terreus culture medium along with three known isocoumarin derivatives, (-)-(3R)-6-methoxymellein (2), (-)-(3R)-6,7-dimethoxymellein (Kigelin) (3) and (3R, 4R)-6,7-dimethoxy-4-hydroxymellein (4). Metabolites 1 and 4 showed significant activity against human pathogenic dermatophytes, Microsporum canis and Trichophyton longifusus. Metabolite 1 also exhibited potent antioxidant activity. The structures of metabolites were characterized on the basis of spectroscopic techniques. 13C NMR data of metabolites 2 - 4 are also being reported for the first time
A Multiarray Induction Tool Optimized for Efficient Wellsite Operation (1995)

Abstract A new multiarray induction tool has been developed as part of the Platform Express,* a suite of tools intended to significantly improve wellsite efficiency. The tool measures formation conductivity with eight arrays ranging in length from 6 in. to 6 ft. Previously published methods1 are used to provide logs with 90% vertical resolutions of 1, 2 and 4 ft, each with depths of investigations of 10, 20, 30, 60 and 90 in. Integral to the tool is a sensor that measures the mud resistivity to provide accurate borehole corrections for the induction logs. The total length of the instrument package is 16 ft. One problem encountered in multiarray induction tools is stick-slip motion of the tool in the borehole. To solve this problem an accelerometer included in the high-efficiency toolstring is used to provide real-time depth correction for nonuniform tool motion for all the tools in the string. In addition, this guarantees that the high-resolution logs are on depth with each other. A special effort has been made to extend multiarray induction technology into more difficult logging conditions. A new algorithm that provides improved logs in very rugose boreholes and salty conductive mud has been developed and applied to the log processing of this tool. Additional features include correction to the resistivity logs for dip or deviation up to 60 degrees and more accurate estimates of Rt in the presence of annulus. The effectiveness of these algorithms has been demonstrated in case studies with both computed and field logs.
Contemporary approaches to idiopathic pulmonary fibrosis (2015)

in M xico, and head of the Interstitial Lung Diseases Study group from 1983. He has made important contributions both in the clinical area as well as in the pathogenic mechanisms of different ILDs, primarily idiopathic pulmonary fibrosis and hypersensitivity pneumonitis.