gebhart/patrepeval huggingface dataset:
Temperature Response of a Magnetic Resonance Imaging Coil Insert for the Navigation of Theranostic Agents in Complex Vascular Networks (2014)

The purpose of this paper is to provide some practical insights regarding the use of a commercially available imaging coil as a magnetic resonance navigation (MRN) propulsion actuator. MRN relies on magnetic resonance imaging (MRI) technology to navigate magnetic therapeutic or imaging agents to a target location. When such a target is accessible only through complex vessel pathways, an imaging gradient coil (IGC) insert can be used to generate high slew rate gradient pulses. Although temperature rise might not be an issue for imaging routines, knowing precisely the temperature coil response is of primary importance for MRN-assisted interventions as it may limit propulsion performance and ultimately lead to system breakdown. This paper reports the impact of four parameters, namely, duty cycle, frequency, amplitude, and gradient direction on the temperature behavior of an IGC with external diameter suitable to fit inside the bore of a clinical MRI scanner and internal diameter appropriate for small animals. A minimum rise time of 300 μs was measured and magnetic gradients up to 325 mT·m <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-1</sup> were generated. The insert can sustain burst-mode propulsion at maximum power for slightly less than 2 min before reaching its maximum admissible temperature. Temperature management is one of the future challenges in MRN research.
Evidence of reduced glutamate in the frontal lobe of HIV‐seropositive patients (2008)

Neurological complications associated with the acquired immunodeficiency syndrome, in particular, HIV-associated dementia, continue to plague those infected. We report our finding that the concentration of brain Glu is reduced in the frontal white matter region in this condition. In addition, our data appear to absolve highly active retroviral therapy (HAART) from blame, as drug-naïve patients were equally affected. Our findings suggest that Glu neurotransmission is abnormal and may be a key target for early interventions to reduce the later incidence of neurocognitive impairment and dementia among HIV-seropositive patients.
A hybrid human and machine resource curation pipeline for the Neuroscience Information Framework (2012)

The breadth of information resources available to researchers on the Internet continues to expand, particularly in light of recently implemented data-sharing policies required by funding agencies. However, the nature of dense, multifaceted neuroscience data and the design of contemporary search engine systems makes efficient, reliable and relevant discovery of such information a significant challenge. This challenge is specifically pertinent for online databases, whose dynamic content is 'hidden' from search engines. The Neuroscience Information Framework (NIF; http://www.neuinfo.org) was funded by the NIH Blueprint for Neuroscience Research to address the problem of finding and utilizing neuroscience-relevant resources such as software tools, data sets, experimental animals and antibodies across the Internet. From the outset, NIF sought to provide an accounting of available resources, whereas developing technical solutions to finding, accessing and utilizing them. The curators therefore, are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping the contents current. In the initial phases of the project, all aspects of the registration and curation processes were manual. However, as the number of resources grew, manual curation became impractical. This report describes our experiences and successes with developing automated resource discovery and semiautomated type characterization with text-mining scripts that facilitate curation team efforts to discover, integrate and display new content. We also describe the DISCO framework, a suite of automated web services that significantly reduce manual curation efforts to periodically check for resource updates. Lastly, we discuss DOMEO, a semi-automated annotation tool that improves the discovery and curation of resources that are not necessarily website-based (i.e. reagents, software tools). Although the ultimate goal of automation was to reduce the workload of the curators, it has resulted in valuable analytic by-products that address accessibility, use and citation of resources that can now be shared with resource owners and the larger scientific community. DATABASE URL: http://neuinfo.org.
DNP-an endothelial cell derived member of the natriuretic peptide family (2000)

DNP is a potent 38 amino acid peptide isolated from the Dendroaspis angusticeps which shares structural similarity with ANP, BNP and CNP as it possesses a 17 amino acid ring structure. Recently, we have reported DNP-like immunoreactivity in human plasma with elevation in congestive heart failure achieving concentrations similar to CNP, an endothelial cell-derived peptide. The goal of the current study was to determine the presence and secretion of DNP in cultured human aortic endothelial cells and its ability to activate cGMP compared to other known natriuretic peptides (NPs). The rationale for these studies was based upon preliminary studies which have detected DNP-like immunoreactivity associated with isolated blood vessels. Immunohistochemistry utilizing a specific DNP antibody revealed markedly positive endothelial cell granular staining which was localized to the perinuclear position. Staining for nonimmune control was negative. Utilizing a specific radioimmunoassay for DNP, we found that DNP was present at a concentration of 82.2 ± 1.2 pg/ml. To determine the biological actions of DNP upon endothelial cell cGMP generation, we stimulated ECs with DNP at 1nM, 10 nM, 100 nM, and 1uM for 60 minutes and compared its action to other NPs. All NPs increased cellular cGMP generation with DNP being the most potent stimulator (p<0.05). The potency of the NPs to stimulate EC cGMP production was DNP>ANP>BNP>CNP. The current studies report for the first time presence and secretion of DNP in human endothelial cells together with documented potent cGMP generating actions. We conclude that DNP may be an additional potent cGMP generating CV peptide of endothelial origin.
Surgical Outcomes in Selective Laminectomy and Conventional Double-Door Laminoplasty for Cervical Spondylotic Myelopathy (2020)

Several postoperative problems have been reported in conventional cervical laminoplasty (C-LAMP), such as loss of cervical curvature, sagittal imbalance, and loss of range of motion (ROM). Selective laminectomy (S-LAM) is a less invasive procedure that may prevent the problems associated with conventional C-LAMP. In this study, the authors prospectively compared neurological outcomes and radiological parameters in C-LAMP and S-LAM for the treatment of cervical spondylotic myelopathy. Fifty-three patients were enrolled, with 25 patients receiving conventional double-door C-LAMP and 28 patients receiving S-LAM. Measured outcomes included operative time, intraoperative blood loss, Japanese Orthopaedic Association score for neurological recovery, cervical sagittal alignment at C2-7, cervical sagittal vertical axis from occiput to C7, C7 slope, and cervical ROM at C2-7. No difference was found in operative time, whereas intraoperative blood loss was significantly less in the S-LAM group (P<.05). No significant difference in neurological recovery was found between the 2 groups. The postoperative C2-7 angle was significantly smaller (P<.05) and cervical sagittal vertical axis greater (P<.01) in the C-LAMP group. Postoperative ROM at C2-7 was greater (P<.01) in the S-LAM group. In the CLAMP group, postoperative kyphotic change was greater in patients with high C7 slope. However, in the S-LAM group, postoperative sagittal alignment was preserved even in patients with high C7 slope. Postoperative cervical alignment, sagittal balance, and cervical ROM were better preserved in the S-LAM group compared with the C-LAMP group. Selective laminectomy is an effective, minimally invasive method for cervical spondylotic myelopathy with spinal cord compression at limited levels. [Orthopedics. 2020;43(4);e311-e315.].
Origin of intramuscular nerve action potential. (1987)

The origin of the intramuscular nerve action potential (INAP) was investigated using conventional surface recording electrodes. The appearance of the INAP was (1) associated with subjective paresthesias, (2) recorded only when the reference electrode (G2) was over an appropriate digital nerve, (3) increased in latency as G2 was placed more distally, (4) blocked by an orthodromic sensory nerve action potential arising from the thumb, and (5) abolished with an anaesthetic block in the digital nerve proximal to G2. The findings indicate that the INAP is recorded by the G2 electrode from the digital nerve.
Effects of surface-active block copolymers with oxyethylene and fluoroalkyl side chains on the antifouling performance of silicone-based films (2016)

Block copolymers made from a poly(dimethyl siloxane) (Si) and a poly(meth)acrylate carrying oxyethylene (EG) or fluoroalkyl (AF) side chains were synthesized and incorporated as surface-active components into a silicone matrix to produce cross-linked films with different surface hydrophilicity/phobicity. Near-edge X-ray absorption fine structure (NEXAFS) studies showed that film surfaces containing Si-EG were largely populated by the siloxane, with the oxyethylene chains present only to a minor extent. In contrast, the fluorinated block was selectively segregated to the polymer-air interface in films containing Si-AF as probed by NEXAFS and X-ray photoelectron spectroscopy (XPS) analyses. Such differences in surface composition were reflected in the biological performance of the coatings. While the films with Si-EG showed a higher removal of both Ulva linza sporelings and Balanus amphitrite juveniles than the silicone control, those with Si-AF exhibited excellent antifouling properties, preventing the settlement of cyprids of B. amphitrite.
Construction of a ‘unigene’ cDNA clone set by oligonucleotide fingerprinting allows access to 25 000 potential sugar beet genes (2002)

Access to the complete gene inventory of an organism is crucial to understanding physiological processes like development, differentiation, pathogenesis, or adaptation to the environment. Transcripts from many active genes are present at low copy numbers. Therefore, procedures that rely on random EST sequencing or on normalisation and subtraction methods have to produce massively redundant data to get access to low-abundance genes. Here, we present an improved oligonucleotide fingerprinting (ofp) approach to the genome of sugar beet (Beta vulgaris), a plant for which practically no molecular information has been available. To identify distinct genes and to provide a representative 'unigene' cDNA set for sugar beet, 159 936 cDNA clones were processed utilizing large-scale, high-throughput data generation and analysis methods. Data analysis yielded 30 444 ofp clusters reflecting the number of different genes in the original cDNA sample. A sample of 10 961 cDNA clones, each representing a different cluster, were selected for sequencing. Standard sequence analysis confirmed that 89% of these EST sequences did represent different genes. These results indicate that the full set of 30 444 ofp clusters represent up to 25 000 genes. We conclude that the ofp analysis pipeline is an accurate and effective way to construct large representative 'unigene' sets for any plant of interest with no requirement for prior molecular sequence data.
A wide field of view radar for Sense and Avoid on UAV using space coloring waveforms (2010)

Up to now, UAV are employed in crisis or war times. For training purposes, some areas are especially attributed for UAV deployment in a limited space area and in a limited time slot. In the future, both for emerging civilian applications and for training purpose, these limitations will no longer be acceptable and UAV will have to be inserted in the general Air Traffic. Thus, “Sense and Avoid” systems will be mandatory. The radar is the most pertinent non-cooperative “all-weather” sensor because it provides, by essence, accurate ranging, direction and closing speed. In this paper, we propose a low cost radar solution based on space coloring waveforms. This design allows the implementation of the radar within the UAV airframe without any moving parts.
Using Stain Decomposition for Nucleus Segmentation on Multisource H&E Slide Images (2021)

The deep learning technique is widely used for whole slide image (WSI) analysis due to its speed and relatively objective results. Nucleus instance segmentation, in which the nuclei in the WSI are individually identified, can provide many useful parameters to assist and accelerate the diagnosis process for pathologists. Hematoxylin and eosin stain (H&E stain) is commonly used on pathology tissue slides to observe the behavior and structure information of cells. However, the color-oriented features of the nuclei vary widely depending on the dye and staining protocol employed and also the scanning system used to obtain the digital WSIs. Accordingly, the proposed lightweight network module attached to the front of an arbitrary network can provide a more robust segmentation performance irrespective of staining protocols employed and scanning circumstances. Notably, the proposed module improves the performance for unseen color-oriented features and thus can benefit the realworld applications, where the WSIs may be collected from multiple hospitals and laboratories.
Biogas upgrading through kinetic separation of carbon dioxide and methane over Rb- and Cs-ZK-5 zeolites (2014)

Kinetic separation of CO<sub>2</sub>from CH<sub>4</sub>over rubidium or cesium-exchanged ZK-5 (KFI) zeolites for upgrade of biogas to renewable fuels.
Interference Alignment with Limited Feedback on Two-cell Interfering Two-User MIMO-MAC (2010)

In this paper, we consider a two-cell interfering two-user multiple-input multiple-output multiple access channel (MIMO-MAC) with limited feedback. We first investigate the multiplexing gain of such channel when users have perfect channel state information at transmitter (CSIT) by exploiting an interference alignment scheme. In addition, we propose a feedback framework for the interference alignment in the limited feedback system. On the basis of the proposed feedback framework, we analyze the rate gap loss and it is shown that in order to keep the same multiplexing gain with the case of perfect CSIT, the number of feedback bits per receiver scales as $B \geq (M\!-1\!)\!\log_{2}(\textsf{SNR})+C$, where $M$ and $C$ denote the number of transmit antennas and a constant, respectively. Throughout the simulation results, it is shown that the sum-rate performance coincides with the derived results.
Growth of Metal Nanocrystals on Nanostructured Metal Oxides−Dramatic Effect of Antimony Doping (2011)

Unusually high loading of noble metal nanoparticles on nanostructured metal oxide surfaces, like inverse titania or tin oxide opals, was achieved by antimony doping of the metal oxide, which bodes well for their use as supports for heterogeneous catalysis and photocatalysis, chemical sensor, and solar cell applications.
Transcranial ultrasound in clinical sonothrombolysis (TUCSON) trial (2009)

Perflutren lipid microS can be safely combined with systemic tPA and ultrasound at a dose of 1.4ml. Safety concerns in the second dose tier may necessitate extended enrollment and further experiments to determine the mechanisms by which microspheres interact with tissues. In both dose tiers, sonothrombolysis with microS and tPA shows a trend toward higher early recanalization and clinical recovery rates compared to standard intravenous tPA therapy. Ann Neurol 2009;66:28-38.
Tepco 2000 MW Combined Cycle Power Plant Construction Progress and Start-Up (1986)

Tokyo Electric Power Company is completing the construction of the first 1,000 MW group in the world’s largest, 2000 MW, combined cycle power plant. The 165 MW single shaft combined cycle systems are being started sequentially. A description of the construction progress, start-up and initial operation of the first 165 MW combined cycle system and the planned completion of the station are presented.
Cover Picture: The Tungstogermanate [Ce20Ge10W100O376(OH)4(H2O)30]56−: A Polyoxometalate Containing 20 Cerium(III) Atoms (Angew. Chem. Int. Ed. 32/2007) (2007)

A gigantic polyoxometalate …︁…︁ [Ce20Ge10W100O376(OH)4(H2O)30]56− (1) was obtained in a classic one-pot synthesis from CeIII ions and the trilacunary precursor [α-GeW9O34]10− in water, as described by U. Kortz and co-workers in their Communication on page 6192 ff. The cover picture shows a possible mechanism of formation by stepwise self-assembly, beginning with the formation of Ce2GeW10 Keggin units, followed by arrangement of five such units into chiral, enantiomeric {Ce2GeW10}5 species, and then dimerization of the R and S forms to give 1.
Spectroscopy, structure, and proton dynamics of 2-hydroxypyridine and its clusters with water and ammonia (1989)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpectroscopy, structure, and proton dynamics of 2-hydroxypyridine and its clusters with water and ammoniaM. R. Nimlos, D. F. Kelley, and E. R. BernsteinCite this: J. Phys. Chem. 1989, 93, 2, 643–651Publication Date (Print):January 1, 1989Publication History Published online1 May 2002Published inissue 1 January 1989https://doi.org/10.1021/j100339a030RIGHTS & PERMISSIONSArticle Views369Altmetric-Citations128LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1016 KB) Get e-Alerts
Filler Distribution and Domain Size of Elastomer Compounds by Solid-State NMR and AFM (2007)

Abstract Solid-state NMR methods were used to characterize the filler distribution in rubber blends and domain size of thermoplastic vulcanizates (TPV). Correlation between filler content and magic angle spinning (MAS) 13 C and 1 H NMR signal linewidth was established, and filler content in each component of the rubber blends was determined. In IIR/BR and BIMS/BR blends, carbon black enriches in BR phase. Comparison of the carbon black enrichment in both blends suggests that BIMS has a slightly stronger interaction with fillers than does IIR. Results obtained from AFM analysis were compared with NMR observations. Spin diffusion NMR was demonstrated to be useful for quantifying the amount of interfacial component in TPV. Its advantages — ease of quantification and high sensitivity for smaller domains — make it a complementary approach to microscopic techniques for elastomer morphology characterization.
An Experimental Investigation on Viscoelastic Behavior in Tunable (2010)

Abstract—In this paper, the viscoelastic behavior of a tunable RF-MEMS resonator and its impacts are studied by means of direct RF measurements for the first time. This tunable resonator consists of one λ/2 coplanar waveguide (CPW) resonator and two nanocrystalline-Ni RF-MEMS varactors. S-parameters of this tunable resonator have been measured for 80 hours under a bi-state bias condition of 0 and 40 V. It is demonstrated that the resonant frequency is shifted by 90 MHz and the varactor deformed by 0.12 μm over the 80 hour period. The gap of the loaded varactor is extracted from the measured S-parameters using finite-element analysis (FEA) tools. A generalized Voigt- Kelvin model is employed to verify the viscoelastic behavior of the resonator. The creep compliance extracted from the RF measurements is in excellent agreement with results in literature. Index Terms—creep, nickel, RF-MEMS, tunable resonator, viscoelastic.
Ink Annotations and their Anchoring in Heterogeneous Digital Documents (2007)

The analysis, especially the anchoring, of free­form ink annotations on mixed­content digital documents is more difficult than that of documents containing only text. In this paper, first, we present our work on analyzing the common user scenarios of ink annotations and their anchoring in such an environment, and we also present a unified way to define and analyze the anchoring of different types of an- notations. Then we describe how our ink parsing system integrates the anchoring of and annotation with the recog- nition of its type. The method can be used in a real­time heterogeneous document analysis system.
Resonant tunneling of holes in Si/GexSi1−x (1991)

The compressional strain in GexSi1−x grown on Si moves the light-hole (LH) band down and the heavy-hole (HH) band up, while the tensile strain in Si grown on GexSi1−x moves the LH band up and the HH band down. In the tunneling structure of Si/GexSi1−x grown on a Si substrate with a GexSi1−x or Si buffer layer, the band offsets of LH and HH are then changed depending on the strain in Si/GexSi1−x, which is influenced by the lattice relaxation of the buffer layer. In this work the Fermi level Ef of the tunneling structure is investigated from the energy band structure calculations to provide information for tunneling current calculations and peak identification in comparison with experimental I-V spectra. When a Si buffer layer is used, only the HH band of the GexSi1−x spacer is found to be filled so that the tunneling current is HH characteristic. With a GexSi1−x buffer layer both LH and HH contribute to the total tunneling current. The effective mass approximation is also investigated for Si/GexSi1−x tunneling structures and a quasiparticle (HH, LH, and the spin-orbital splitoff) tunneling picture is justified for theoretical analysis.
Metacarpal shaft fixation: a biomechanical comparison of dorsal plating, lag screws, and headless compression screws (2021)

Basic Science Study, Biomechanics.