gebhart/patrepeval huggingface dataset:
Let's call it “color‐gamut rendering” (2007)

Abstract The term “color gamut” historically has been associated with color output such as optimal color stimuli and additive and subtractive imaging systems. Recently, this term has been used with input devices such as scanners and digital cameras. It is proposed that the term “color‐gamut rendering” should be used instead of input devices. This clarifies the distinction between input (analysis) and output (synthesis) color systems in terms of the effect of an input system on defining the colorimetric properties of an output system. © 2007 Wiley Periodicals, Inc. Col Res Appl, 32, 334–335, 2007
VLC Systems with Fixed-Rate Transmissions under Statistical Queueing Constraints (2018)

Cross-layer analysis has been gaining an increasing attention as a powerful tool to study and assess different quality-of-service (QoS) mechanisms in wireless networks. Regarding the physical and data-link layers, in this paper we provide a cross-layer study for visible light communication (VLC) systems operating under statistical QoS constraints, which are inflicted as limits on the delay violation and buffer overflow probabilities. We assume that the VLC access point (AP) is unaware of the channel conditions, thus the AP sends the data at a fixed rate. Under this assumption, and considering an ON-OFF data source, we employ the maximum average data arrival rate at the AP buffer and the non-asymptotic bounds on buffering delay as the main performance measures. Through numerical results, we illustrate the impacts of different physical and data-link parameters on the system performance.
Dynamic changes in gene-to-gene regulatory networks in response to SARS-CoV-2 infection (2021)

The current pandemic of SARS-CoV-2 has caused extensive damage to society. The characterization of SARS-CoV-2 profiles has been addressed by researchers globally with the aim of resolving this disruptive crisis. This investigation process is indispensable to understand how SARS-CoV-2 behaves in human host cells. However, little is known about the systematic molecular mechanisms involved in the effects of SARS-CoV-2 infection on human host cells. Here, we present gene-to-gene regulatory networks in response to SARS-CoV-2 using a Bayesian network. We examined the dynamic changes in the SARS-CoV-2-purturbated networks established by our proposed framework for gene network analysis, thus revealing that interferon signaling gradually switched to the subsequent inflammatory cytokine signaling cascades. Furthermore, we succeeded in capturing a COVID-19 patient-specific network in which transduction of these signals was concurrently induced. This enabled us to explore the local regulatory systems influenced by SARS-CoV-2 in host cells more precisely at an individual level. Our panel of network analyses has provided new insights into SARS-CoV-2 research from the perspective of cellular systems.
Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy (2019)

The prognosis of advanced/recurrent cervical cancer patients remains poor. We analyzed 54 fresh-frozen and 15 primary cervical cancer cell lines, along with matched-normal DNA, by whole-exome sequencing (WES), most of which harboring Human-Papillomavirus-type-16/18. We found recurrent somatic missense mutations in 22 genes (including PIK3CA, ERBB2, and GNAS) and a widespread APOBEC cytidine deaminase mutagenesis pattern (TCW motif) in both adenocarcinoma (ACC) and squamous cell carcinomas (SCCs). Somatic copy number variants (CNVs) identified 12 copy number gains and 40 losses, occurring more often than expected by chance, with the most frequent events in pathways similar to those found from analysis of single nucleotide variants (SNVs), including the ERBB2/PI3K/AKT/mTOR, apoptosis, chromatin remodeling, and cell cycle. To validate specific SNVs as targets, we took advantage of primary cervical tumor cell lines and xenografts to preclinically evaluate the activity of pan-HER (afatinib and neratinib) and PIK3CA (copanlisib) inhibitors, alone and in combination, against tumors harboring alterations in the ERBB2/PI3K/AKT/mTOR pathway (71%). Tumors harboring <i>ERBB2</i> (5.8%) domain mutations were significantly more sensitive to single agents afatinib or neratinib when compared to wild-type tumors in preclinical in vitro and in vivo models (<i>P</i> = 0.001). In contrast, pan-HER and PIK3CA inhibitors demonstrated limited in vitro activity and were only transiently effective in controlling in vivo growth of PIK3CA-mutated cervical cancer xenografts. Importantly, combinations of copanlisib and neratinib were highly synergistic, inducing long-lasting regression of tumors harboring alterations in the ERBB2/PI3K/AKT/mTOR pathway. These findings define the genetic landscape of cervical cancer, suggesting that a large subset of cervical tumors might benefit from existing ERBB2/PIK3CA/AKT/mTOR-targeted drugs.
Electron anions and the glass transition temperature (2016)

Properties of glasses are typically controlled by judicious selection of the glass-forming and glass-modifying constituents. Through an experimental and computational study of the crystalline, molten, and amorphous [Ca12Al14O32](2+) ⋅ (e(-))2, we demonstrate that electron anions in this system behave as glass modifiers that strongly affect solidification dynamics, the glass transition temperature, and spectroscopic properties of the resultant amorphous material. The concentration of such electron anions is a consequential control parameter: It invokes materials evolution pathways and properties not available in conventional glasses, which opens a unique avenue in rational materials design.
BRL 34915 (cromakalim) activates ATP-sensitive K+ current in cardiac muscle. (1988)

The mechanism by which the antihypertensive agent BRL 34915 (cromakalim) affects action potential duration (APD) and effective refractory period (ERP) in isolated cardiac muscle was investigated. BRL 34915 (greater than or equal to 3 microM) shortened ERP of ferret (Mustela putorius furo) and guinea pig (Cavia porcellus) papillary muscles in a concentration-dependent fashion. The reduction in ERP resulted from a decrease in APD. ERP and APD of papillary muscles were also reduced during hypoxia produced by bubbling the physiological bathing solution with N2 instead of O2. Reduction of APD during hypoxia has previously been attributed to activation of ATP-sensitive K+ channels in heart. Glyburide, an inhibitor of ATP-sensitive K+ channels, prevented or reversed the shortening of ERP and APD produced by hypoxia and BRL 34915, respectively. These results suggest that BRL 34915 acts by opening ATP-sensitive K+ channels in heart. The actions of BRL 34915 were temperature-dependent, decreasing ERP 64% at 37 degrees C, but having no effect at 22 degrees C. The effect of BRL 34915 on K+ currents was tested directly in voltage-clamped guinea pig ventricular myocytes. As observed with the papillary muscles, BRL 34915 was without effect at 22 degrees C. At 36 degrees C, BRL 34915 (after a delay) increased outward currents positive to, and less so at potentials negative to, the K+ current reversal potential. The normal inwardly rectifying current-voltage relationship for peak K+ currents during 200-msec pulses was changed to one that was nearly ohmic. The current activated by BRL 34915 was blocked by glyburide. The data support the hypothesis that BRL 34915, like hypoxia, activates ATP-sensitive K+ channels in the heart. Based upon the profound temperature sensitivity of BRL 34915 action, this activation may be indirect, perhaps by means of modulation of an enzymatic activity that regulates gating of these channels. BRL 34915 and glyburide will be valuable tools for studying the role of ATP-sensitive K+ channels in normal and abnormal cardiac function.
Delay and energy optimization in multilevel balanced WSNs for landslide monitoring (2016)

In most of the real world wireless sensor network deployments, the energy utilization is a critical factor as the nodes are battery powered. In most of the real-world deployments it is observed that the sensing subsystem consumes higher power. In order to extend the lifetime of such systems it is required to reduce the sensing energy than communication energy. We have deployed a system for monitoring Landslides in India consists of 150 geo-physical sensors and used solar panels to power these sensor nodes. The decision making in favor of Landslide occurrence is based on the maximum values obtained from the high priority sensors. As this maximum value is not frequently changing in the deployment, locating the sensor node with maximum value allows us to switch off the other sensors for a predetermined period of time. This work proposes an optimal balanced network topology for delay minimization by parallelizing data aggregation operation in each sub-network. The sensor node switch off schemes on the top of delay minimized topology enables the optimal utilization of the available solar power. The analysis of these mechanisms shows that, more number of nodes can be powered with the available source of energy and can increase the network life time.
BEP Analysis of OFDM Relay Links with Nonlinear Power Amplifiers (2010)

This paper studies the performance of a two-hop infrastructure-based relay link. The relay operates in a half-duplex mode using an amplify-and-forward protocol. Considering transmission of OFDM signals with nonlinear power amplifiers (PAs), we determine exact closed-form expressions for end-to-end bit error probabilities (BEPs). The expressions allow us to analyze the effect of nonlinear distortion as well as the special case of linear PAs. Furthermore, we derive asymptotic BEP floor values which illustrate how the end-to-end performance is limited by both the nonlinear PA distortion and the weakest hop. Our discussion indicates that the influence of the nonlinear distortion can be mitigated by properly adjusting the PA back-offs.
Uniform Complementary Resistive Switching in Tantalum Oxide Using Current Sweeps (2012)

Tantalum oxide (TaO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> ) is an advantageous material system to realize complementary resistive switches, but the ON-window starts to shrink after a few cycles in the voltage sweep mode. A power analysis reveals the presence of power boosts during conventional voltage sweeps in the nonswitching part cell. This power stress is significantly reduced by the use of current sweeps with voltage compliance, leading to very reproducible switching. The endurance is raised to >; 30000 cycles.
A Framework for Leading the Transformation to Performance Excellence Part I (2013)

The results of a qualitative multiple case study based on in-depth interviews with 14 CEOs who led successful organization transformations, resulting in recognition as a Malcolm Baldrige National Quality Award recipient.
A noninvasive test for vesico‐ureteric reflux in children (2001)

This noninvasive diagnostic technique detected VUR in 35 of 37 refluxing units and verified no reflux in 16 of 17 units without VUR. Further refinements may allow this technology to be used in all children with suspected VUR.
Molecular Aspects of Anticancer Drug-DNA Interactions (1994)

DNA topoisomerases, K. Kohn and R. Ralph the cellular and molecular pharmacology of the anthrapyrazole antitumour agent, D.R. Newell and L.H. Patterson calicheamicin, G.A. Elistad and W.D. Ding molecular pharmacology of intercalator - groove binder hybrid molecules, C. Bailly and J.P. Henichart bleomycins - mechanism of polynucleotide recognition and oxidative degradation, A. Natrajan and S.M. Hecht kinetic analysis of drug-nucleic acid binding modes - absolute rates and effects of salt concentration, W.D. Wilson and F.A. Tanions acridine-based anti-cancer drugs, W.A. Denny and B.C. Baguley the mitomycins - natural cross-linkers of DNA, M. Tomasz.
Directional Scattering and Hydrogen Sensing by Bimetallic Pd–Au Nanoantennas (2012)

Nanoplasmonic sensing is typically based on quantification of changes in optical extinction or scattering spectra. Here we explore the possibility of facile self-referenced hydrogen sensing based on angle-resolved spectroscopy. We found that heterodimers built from closely spaced gold and palladium nanodisks exhibit pronounced directional scattering, that is, for particular wavelengths, much more light is scattered toward the Au than toward the Pd particle in a dimer. The effect is due to optical phase shifts associated with the material asymmetry and therefore highly sensitive to changes in the permittivity of Pd induced by hydrogen loading. In a wider perspective, the results suggest that directional scattering from bimetallic antennas, and material asymmetry in general, may offer many new routes toward novel nanophotonic sensing schemes.
Decomposition of trimethylgallium and adduct formation in a metalorganic vapor phase epitaxy reactor analyzed by high‐resolution gas monitoring system (2017)

In this study, by using time‐of‐flight (TOF) high‐resolution and high‐sensitivity mass spectrometry measurements, the decomposition of trimethylgallium into dimethylgallium and monomethylgallium along with its adduct formation with NH x in a commercially available horizontal metalorganic vapor‐phase epitaxy (MOVPE) reactor with a resistive heater was investigated and observed in more detail than previously reported. The results confirmed the use of the TOF monitoring system in analyzing the elementary reaction process in actual MOVPE systems.
Superfast supercomputer-class on-board processing for visual sensor NMD applications (2001)

A new concept of pattern recognition is presented, based on novel supercomputer-class processing for National Missile Defense (NMD) visual sensing.
NUCLEAR ENVELOPE GLUCOSE-6-PHOSPHATASE FROM CONTROL AND THIOACETAMIDE TREATED LIVER (1994)

Conference Article| February 01 1994 NUCLEAR ENVELOPE GLUCOSE-6-PHOSPHATASE FROM CONTROL AND THIOACETAMIDE TREATED LIVER Freddy Gonzalez-Mujica; Freddy Gonzalez-Mujica °Catedra de Bioquimica, Instituto de Medicina Experimental Universidad Central, Apartado 50.587 Sabana, Grande Caracas, Venezuela Search for other works by this author on: This Site PubMed Google Scholar Norma Motta; Norma Motta °Catedra de Bioquimica, Instituto de Medicina Experimental Universidad Central, Apartado 50.587 Sabana, Grande Caracas, Venezuela Search for other works by this author on: This Site PubMed Google Scholar Ian Waddell; Ian Waddell *Department of Obstetrics and Gynaecology, Ninewells Hospital and Medical School, Dundee, DD1 9SY Search for other works by this author on: This Site PubMed Google Scholar Ann Burchell Ann Burchell *Department of Obstetrics and Gynaecology, Ninewells Hospital and Medical School, Dundee, DD1 9SY Search for other works by this author on: This Site PubMed Google Scholar Biochem Soc Trans (1994) 22 (1): 40S. https://doi.org/10.1042/bst022040s Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Facebook Twitter LinkedIn MailTo Cite Icon Cite Get Permissions Citation Freddy Gonzalez-Mujica, Norma Motta, Ian Waddell, Ann Burchell; NUCLEAR ENVELOPE GLUCOSE-6-PHOSPHATASE FROM CONTROL AND THIOACETAMIDE TREATED LIVER. Biochem Soc Trans 1 February 1994; 22 (1): 40S. doi: https://doi.org/10.1042/bst022040s Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAll JournalsBiochemical Society Transactions Search Advanced Search This content is only available as a PDF. © 1994 Biochemical Society1994 Article PDF first page preview Close Modal You do not currently have access to this content.
Acoustic biomolecules enhance hemodynamic functional ultrasound imaging of neural activity (2019)

ABSTRACT Hemodynamic functional ultrasound imaging (fUS) of neural activity provides a unique combination of spatial coverage, spatiotemporal resolution and compatibility with freely moving animals. However, deep and transcranial monitoring of brain activity and the imaging of dynamics in slow-flowing blood vessels remains challenging. To enhance fUS capabilities, we introduce biomolecular hemodynamic enhancers based on gas vesicles (GVs), genetically encodable ultrasound contrast agents derived from buoyant photosynthetic microorganisms. We show that intravenously infused GVs enhance ultrafast Doppler ultrasound contrast and visually-evoked hemodynamic contrast in transcranial fUS of the mouse brain. This hemodynamic contrast enhancement is smoother than that provided by conventional microbubbles, allowing GVs to more reliably amplify neuroimaging signals.
Selection Criteria and Screening of Potential Biomass-Derived Streams as Fuel Blendstocks for Advanced Spark-Ignition Engines (2017)

&lt;div class="section abstract"&gt;&lt;div class="htmlview paragraph"&gt;We describe a study to identify potential biofuels that enable advanced spark ignition (SI) engine efficiency strategies to be pursued more aggressively. A list of potential biomass-derived blendstocks was developed. An online database of properties and characteristics of these bioblendstocks was created and populated. Fuel properties were determined by measurement, model prediction, or literature review. Screening criteria were developed to determine if a bioblendstock met the requirements for advanced SI engines. Criteria included melting point (or cloud point) &amp;lt; -10°C and boiling point (or T90) &amp;lt;165°C. Compounds insoluble or poorly soluble in hydrocarbon were eliminated from consideration, as were those known to cause corrosion (carboxylic acids or high acid number mixtures) and those with hazard classification as known or suspected carcinogens or reproductive toxins. Compounds predicted to be less anaerobically biodegradable than methyl-tert-butyl ether with water solubility greater than 10,000 mg/L were also eliminated. A minimum Research octane number (RON) of 98 was applied. These criteria produced a list of 40 bioblendstocks with promising properties. Additional property data, including Motor octane number (MON), heat of vaporization, and lower heating value, were acquired for these bioblendstocks. A subset of the bioblendstocks representing all functional groups were blended into gasoline or a gasoline surrogate to measure their effect on vapor pressure, distillation curve, oxidation stability, RON, and MON. For blending into a conventional or reformulated blendstock for E10 blending, ethanol, 2-butanol, isobutanol, and diisobutylene have the most desirable properties for blending of a high-octane advanced SI engine fuel.&lt;/div&gt;&lt;/div&gt;
2′‐Fluoro RNA Shows Increased Watson–Crick H‐Bonding Strength and Stacking Relative to RNA: Evidence from NMR and Thermodynamic Data (2012)

The way it is: Incorporation of 2′-deoxy-2′-fluororibonucleotides (2′-F RNA) into RNA oligomers leads to a marked increase in duplex stability. Using NMR spectroscopy (see picture) with native (red circles) and 2′-F modified (black squares) RNA duplexes, and UV melting and osmotic stress experiments the higher stability of 2′-F RNA relative to RNA is shown to be the result of both increased Watson–Crick H-bonding strength and favorable base stacking.
Addressing the energy crisis: using microbes to make biofuels (2022)

Much of the energy being used to power our lives comes from fossil fuels such as coal, natural gas and petroleum. These energy sources are non-renewable, are being exhausted and also pollute the air, water and soil with toxic chemicals. Their mining, transportation, refining and use are associated with a large carbon footprint that contributes significantly to global warming. In addition, the geopolitical complexities surrounding the main fossil fuel producers create risks and uncertainties around the world. Replacing fossil fuels with clean, renewable forms of energy is paramount to creating a sustainable and healthy future, and for laying the foundations for global political stability and prosperity. Using biomass from plants, microbes can produce biofuels that are identical to or perform as well as fossil fuels. In addition of creating sustainable energy, advancing the biofuel industry will create new, high-quality rural jobs whilst improving energy security.
Collisional desorption of NO by fast O atoms (1993)

Surface‐adsorbed NO figures largely in the mechanism that produces visible glow around spacecraft in low Earth orbit (LEO). In view of the potential interference to optical observations such a glow represents, we have investigated the collision‐induced desorption of NO from Al, Ni, and Z306 Chemglaze®‐coated surfaces at 96 K by hyperthermal (8 km/s) oxygen atoms. The removal of surface NO was followed by the monitoring of the visible fluorescence of electronically excited NO 2 * produced through the surface‐mediated reaction O+NO. A variability in collisional desorption rate with material was observed. The limited data suggest a removal efficiency of 4 to 8% of the impinging O atom flux. Implications for the atmospheric scouring of contaminants from external surfaces of LEO spacecraft are discussed.
Structural and Optical Properties of Cs2AgBiBr6 Double Perovskite (2018)

We present a comprehensive study of the relationship between the crystal structure and optoelectronic properties of the double perovskite Cs2AgBiBr6, which has emerged as a promising candidate for photovoltaic devices. On the basis of single-crystal/powder X-ray diffraction and neutron powder diffraction, we have revealed the presence of a structural phase transition at Ts ≈ 122 K between the room-temperature cubic structure (space group Fm3̅m) and a new low-temperature tetragonal structure (I4/m). From reflectivity measurements we found that the peak exciton energy Eex ≈ 2.85 eV near the direct gap shifts proportionally to the tetragonal strain, which is consistent with the Eex being primarily controlled by a rotational degree of freedom of the crystal structure, thus by the angle Bi–Ag–Br. We observed the time-resolved photoluminescence kinetics and we found that, among the relaxation channels, a fast one is mainly present in the tetragonal phase, suggesting that its origin may lie in the formation of tetragonal twin domains.
<title>Image reconstruction of continuously varying objects and simulated breast cancer lesions</title> (1999)

Numerical simulations of near-infrared diffusion tomography are used to reconstruct absorption and scattering images of continuously varying objects and simulated breast cancer lesions. The breast cancer lesions are modeled using chromophore levels derived from typical breast anatomy and an approximation for breast cancer lesions based on contemporary investigations of tissue/tumor optical properties. Images of hemoglobin concentration and oxygenation are derived using least squares regressions on multiple wavelength near-infrared absorption images. The simulations are performed using finite element based iterative reconstructions. The results are compared with in vivo measurements of breast cancer patients acquired using near-infrared diffusion tomography.