gebhart/patrepeval huggingface dataset:
Timed Up and Go test phases as predictors of future falls in community-dwelling older adults (2022)

Abstract Introduction The Timed Up and Go (TUG) is a test widely used to assess the risk of falls in older adults. Although it is a complex task, only the total TUG time has been used for evaluation. The widespread use of smartphones has provided the development of applications for monitoring diagnostic procedures. Objective To analyze the ability to predict future falls in older adults. Methods A cohort study (1 year) of 42 participants using the sTUG Doctor. Fall events during 1-year follow-up were monitored by telephone. The number of days between assessment and first fall or last contact was calculated for survival analysis, assessed by unadjusted and adjusted Cox proportional hazards regression models. Tests with p &lt;5 % were considered statistically significant and between 5% and 10% were indicative of significance (Epi-Info™ 7.2). Results Falls were observed in 22 (52.38%) participants (fallers). The results indicated that cognitive impairment, depressive symptoms, women, and participants with fear of falling (FES-I) were more likely to fall. Fallers performed worse on all sTUG Doctor phases. Hazard ratios for predicting falls were significant for total TUG time (1.35; p = 0.029) and total number of steps (1.52; p = 0.057). Total TUG time remained significant when adjusted for sex, age group, FES-I, and depression level. Conclusion The sTUG Doctor was an important tool to predict falls in community-dwelling older adults.
The effect of radial head fracture size on elbow kinematics and stability (2004)

This study determined the effect of radial head fracture size and ligament injury on elbow kinematics. Eight cadaveric upper extremities were studied in an in vitro elbow simulator. Testing was performed with ligaments intact, with the medial collateral (MCL) or lateral collateral (LCL) ligament detached, and with both the MCL and LCL detached. Thirty degree wedges were sequentially removed from the anterolateral radial head up to 120 degrees . Valgus angulation and external rotation of the ulna relative to the humerus were determined for passive motion, active motion, and pivot shift testing with the arm in a vertical (dependent) orientation. Maximum varus-valgus laxity was calculated from measurements of varus and valgus angulation with the arm in horizontal gravity-loaded positions. No effect of increasing radial head fracture size was observed on valgus angulation during passive and active motion in the dependent position. In supination, external rotation increased with increasing fracture size during passive motion with LCL deficiency and both MCL and LCL deficiency. With intact ligaments, maximum varus-valgus laxity increased with increasing radial head fracture size. With ligament disruption, elbows were grossly unstable, and no effect of increasing radial head fracture size occurred. During pivot shift testing, performed with the ligaments intact, subtle instability was noted after resection of one-third of the radial head. In this in vitro biomechanical study, small subtle effects of radial head fracture size on elbow kinematics and stability were seen in both the ligament intact and ligament deficient elbows. These data suggest that fixation of displaced radial head fractures less than or equal to one-third of the articular diameter may have some biomechanical advantages; however, clinical correlation is required.
Editorial (1991)

127 Editorial When this issue of MISSION STUDIES is published, it is less than a year to go to our VIII IAMS Conference to take place in Hawaii, August 4-11 (12),1992. We hope you have already taken note of this important date. Some have raised the question why we go to Hawaii which has the reputa- tion of being the pleasure ground of the rich. Is this a good place for an international conference of missiologists to meet? Allow me to share some of the considerations which made the IAMS Executive take this decision. Those present at our last conference
Happy Birthday, HAL! (1997)

am a HAL 9000 computer, production number 3. I became operational at the HAL plant in Urbana, Illinois, on January 12, 1997.ý2001: A Space Odyssey
Formalizing meta-programming techniques to reconcile heterogeneous scheduling disciplines in open distributed real-time systems (2002)

In open distributed real-time and embedded (DRE) systems, different ORB endsystems may use different scheduling disciplines. To ensure appropriate end-to-end application behavior in an open architecture, DRE systems must enforce an ordering on activities originating in an endsystem and activities that migrate there, based on the relative importance of these activities. This paper describes the meta-programming techniques applied in Juno, which extends Real-time CORBA to enhance the openness of DRE systems with respect to their scheduling disciplines by enabling dynamic ordering of priority equivalence classes. We use the forthcoming OMG Real-Time CORBA 2.0: Dynamic Scheduling Joint Final Submission (RT-CORBA 2.0 JFS) to illustrate our techniques.
Atomic Layer Deposition of TiO2on Graphene for Supercapacitors (2012)

A nano-scaled coating of titanium oxide (TiO2) on graphene (G) has been achieved via a novel atomic layer deposition (ALD) method. As a potential supercapacitor material, the TiO2-G composites exhibited a capacity of 75 F/g and 84 F/g at a scan rate of 10 mV/s for composites grown using 50 and 100 ALD cycles, respectively. The nearly identical Nyquist plots of the TiO2-G composites compared with those of pure graphene demonstrated that the composites possess excellent conductivity for charge transfer and open structures for ion diffusion. In addition, even with 3-4 times additional mass loading (maximum 3.22 mg/cm2), the composites exhibit no obvious degradation with respect to the electrochemical performance. This ALD approach presents a promising route to synthesize advanced graphene-based nanocomposites for supercapacitor applications.
The response to IT complexity: autonomic computing (2004)

Autonomic computing (AC) is an initiative that addresses the challenge of managing information technology (IT). The AC approach is to develop technologies and methodologies that make systems more self-managing and more resilient to changes in configurations, workloads and other factors. By so doing, AC reduce the total cost of ownership of IT systems, enable IT systems to deliver business value more rapidly, and increase the quality of service of IT systems. This work highlights the concepts of AC, the business drivers behind it and how the domains of AC address the challenges in today's IT environments. It describes principles of an overarching unified architecture, common building blocks for autonomic systems, some areas of progress and the challenges ahead.
Inclusive-photon production and its dependence on photon isolation in pp collisions at $$ \sqrt{s} $$ = 13 TeV using 139 fb−1 of ATLAS data (2023)

A bstract Measurements of differential cross sections are presented for inclusive isolated-photon production in pp collisions at a centre-of-mass energy of 13 TeV provided by the LHC and using 139 fb − 1 of data recorded by the ATLAS experiment. The cross sections are measured as functions of the photon transverse energy in different regions of photon pseudorapidity. The photons are required to be isolated by means of a fixed-cone method with two different cone radii. The dependence of the inclusive-photon production on the photon isolation is investigated by measuring the fiducial cross sections as functions of the isolation-cone radius and the ratios of the differential cross sections with different radii in different regions of photon pseudorapidity. The results presented in this paper constitute an improvement with respect to those published by ATLAS earlier: the measurements are provided for different isolation radii and with a more granular segmentation in photon pseudorapidity that can be exploited in improving the determination of the proton parton distribution functions. These improvements provide a more in-depth test of the theoretical predictions. Next-to-leading-order QCD predictions from JETPHOX and SHERPA and next-to-next-to-leading-order QCD predictions from NNLOJET are compared to the measurements, using several parameterisations of the proton parton distribution functions. The measured cross sections are well described by the fixed-order QCD predictions within the experimental and theoretical uncertainties in most of the investigated phase-space region.
<title>Single-molecule detection by two-photon excitation of fluorescence</title> (1997)

Using a mode-locked titanium: sapphire laser at 700 nm for two-photon excitation we studied fluorescence bursts from individual coumarin 120 molecules in water and triacetin. Fluorescence lifetimes and multichannel scaler traces have been measured simultaneously. Due to the fact that scattered excitation light as well as Raman scattered photons can be suppressed by a short-pass filter a very low background level was achieved. To identify the fluorophore by its characteristic fluorescence lifetime the time-resolved fluorescence signals were analyzed by a maximum likelihood estimator. The obtained average fluorescence lifetimes (tau) <SUB>av</SUB> equals 4.8 +/- 1.2 ns for coumarin 120 in water and (tau) <SUB>av</SUB> equals 3.3 +/- 0.6 for coumarin 120 in triacetin are in good agreement with results obtained from separate measurements at higher concentrations.
Supplementary Figure 3 from <i>De Novo</i> Design of a Tumor-Penetrating Peptide (2023)

&lt;p&gt;PDF file - 517K, iNGR binding is not mediated by alphav integrins&lt;/p&gt;
Path Sampling Calculation of Methane Diffusivity in Natural Gas Hydrates from a Water-Vacancy Assisted Mechanism (2008)

Increased interest in natural gas hydrate formation and decomposition, coupled with experimental difficulties in diffusion measurements, makes estimating transport properties in hydrates an important technological challenge. This research uses an equilibrium path sampling method for free energy calculations [Radhakrishnan, R.; Schlick, T. J. Chem. Phys. 2004, 121, 2436] with reactive flux and kinetic Monte Carlo simulations to estimate the methane diffusivity within a structure I gas hydrate crystal. The calculations support a water-vacancy assisted diffusion mechanism where methane hops from an occupied "donor" cage to an adjacent "acceptor" cage. For pathways between cages that are separated by five-membered water rings, the free energy landscape has a high barrier with a shallow well at the top. For pathways between cages that are separated by six-membered water rings, the free energy calculations show a lower barrier with no stable intermediate. Reactive flux simulations confirm that many reactive trajectories become trapped in the shallow intermediate at the top of the barrier leading to a small transmission coefficient for these paths. Stable intermediate configurations are identified as doubly occupied off-pathway cages and methane occupying the position of a water vacancy. Rate constants are computed and used to simulate self-diffusion with a kinetic Monte Carlo algorithm. Self-diffusion rates were much slower than the Einstein estimate because of lattice connectivity and methane's preference for large cages over small cages. Specifically, the fastest pathways for methane hopping are arranged in parallel (nonintersecting) channels, so methane must hop via a slow pathway to escape the channel. From a computational perspective, this paper demonstrates that equilibrium path sampling can compute free energies for a broader class of coordinates than umbrella sampling with molecular dynamics. From a technological perspective, this paper provides one estimate for an important transport property that has been difficult to measure. In a hydrate I crystal at 250 K with nearly all cages occupied by methane, we estimate D approximately 7 x 10(-15) X m(2)/s where X is the fraction of unoccupied cages.
Supplementary Figure S6 from Integrated Human and Murine Clinical Study Establishes Clinical Efficacy of Ruxolitinib in Chronic Myelomonocytic Leukemia (2023)

&lt;p&gt;Supplementary Figure S6 compares various metrics assessed at time of necropsy in patient-derived xenograft mice.&lt;/p&gt;
Optimization of a Series-Parallel MEMS Resonators Configuration for Passive Voltage Amplification in Wake-up Radios (2020)

This paper reports on the analytical and numerical optimization of a Series-Parallel configuration (L-network) of Microelectromechanical (MEM) resonators for passive voltage amplification in Wake-up Receivers (WuRx). A thorough discussion of the working principle of the L-network compared to a more traditional series configuration and its analytical description is reported. The numerical simulations of MEMS-based matching networks implemented at the GSM-850 band are also discussed, showing that an asymmetrical L-network configuration outperform a conventional series network for different conditions of resonator performance (Figure of Merit) and capacitive load.
Photophysics of atomic magnesium isolated in solid methane and perdeuteromethane. II. Temperature dependence of steady state and time-resolved luminescence (1988)

The visible emission resulting from photoexcitation of the first allowed singlet resonance transition of atomic magnesium isolated in the solid methanes is analyzed with spectral and time resolution. Two emission bands are observed in both solid methane (CH4) and solid perdeuteromethane (CD4) at 516 and 560 nm. The measured radiative lifetimes of the two bands are 12 and 19 ms, respectively, and independent of isotopic variation of the host. On the basis of their spectral position and radiative lifetimes, the emission features are assigned to the spin-forbidden 3P–1S intercombination band of atomic magnesium. Emission spectra recorded at various temperatures in the range 12–33 K were found to show reversible temperature dependence whereby the intensity of the higher energy 516 nm band decreased monotonically with a concomitant increase in that of the lower energy 560 nm band. Time-resolved measurements of the two bands in Mg/CH4 and Mg/CD4 show that the radiative lifetime of the 516 nm band decreases with increasing temperature while that of the 560 nm band remains constant but showing a rise time component. The magnitude of this rise time is correlated with that of the decreasing lifetime of the 516 nm band. With a combination of the temperature dependence observed in the radiative lifetimes and spectral intensities of the 516 and 560 nm emission bands in the Mg/CH4 and Mg/CD4 systems, dynamical information is extracted which allows for the creation of a simple kinetic model and an identification of the mechanism giving rise to this temperature dependent phenomenon. The experimental data is found to exhibit linear behavior on an Arrhenius plot indicating an activated process of population interconversion between the emitting levels. In solid methane the barrier in this activated process is 177 and 125 cm−1 in solid perdeuteromethane. The origin of this process is discussed in terms of (a) structural phase transitions of the solid methanes and (b) the effect of strong Jahn–Teller coupling between phonon modes of the solid methane host and the spin triplet electronic state of the atomic magnesium guest yielding symmetry-distinct minima on this surface. The lengthened values of the measured radiative lifetimes in the solid methanes, indicate population equilibration amongst the total degeneracy of the triplet state J sublevels of atomic magnesium in these solids. Because of the extremely low temperatures at which the experiment is conducted, extensive orbital reduction factors are implied to achieve such equilibration conditions. This is a manifestation of very strong Jahn–Teller coupling, a necessary condition for the stabilization of symmetry-distinct minima on the triplet spin state surface and the mechanism proposed to explain the presence of the temperature dependent emission features.
Robotic Deep Rolling With Iterative Learning Motion and Force Control (2020)

Large industrial robots offer an attractive option for deep rolling in terms of cost and flexibility. These robots are typically designed for fast and precise motion, but may be commanded to perform force control by adjusting the position setpoint based on the measurements from a wrist-mounted force/torque sensor. Contact force during deep rolling may be as high as 2000 N. The force control performance is affected by robot dynamics, robot joint servo controllers, and motion-induced inertial force. In this letter, we compare three deep rolling force control strategies: position-based rolling with open-loop force control, impedance control, and gradient-based iterative learning control (ILC). Open loop force control is easy to implement but does not correct for any force deviation. Impedance control uses force feedback, but does not track well non-constant force profiles. The ILC augments the impedance control by updating the commanded motion and force profiles based on the motion and force error trajectories in the previous iteration. The update is based on the gradient of the motion and force trajectories with respect to the commanded motion and force. We show that this gradient may be generated experimentally without the need of an explicit model. This is possible because the mapping from the commanded joint motion to the actual joint motion is nearly identical for all joints in industrial robots. We have evaluated the approach on the physical testbed using an ABB robot and demonstrated the convergence of the ILC scheme. The final ILC tracking performance of a trapezoidal force profile improves by over 70% in terms of the RMS error compared with the impedance controller.
A universal vaccine against influenza. (2006)

Twenty per cent of the world's population falls ill. One in every hundred of those ill is hospitalized (if enough beds are available). Seven million deaths occur in a few months and 28 million are hospitalized. This is how the next influenza pandemic might look, according to optimistic estimates. Estimates from other models are far more frightening, but even this best-case scenario is cause for considerable concern.
Exploiting syntactic patterns as clues in zero-anaphora resolution (2006)

We approach the zero-anaphora resolution problem by decomposing it into intra-sentential and inter-sentential zero-anaphora resolution. For the former problem, syntactic patterns of the appearance of zero-pronouns and their antecedents are useful clues. Taking Japanese as a target language, we empirically demonstrate that incorporating rich syntactic pattern features in a state-of-the-art learning-based anaphora resolution model dramatically improves the accuracy of intra-sentential zero-anaphora, which consequently improves the overall performance of zero-anaphora resolution.
Symmetry Induced Heteroclinic Cycles in Coupled Sensor Devices (2012)

In this paper we discuss the existence and stability of heteroclinic cycles in coupled systems and show how they canbeexploitedto designandfabricate anew generationof highly-sensitive,low-powered, sensor devices. More specifically, we present theoretical and experimental proof of concept that coupling-induced oscillations located near the bifurcation point of a heteroclinic cycle can significantly enhance the sensitivity of an array of magnetic sensors. In particular, we consider arrays made up of fluxgate magnetometers inductively coupled through electronic circuits.
Clulow, Adam The Company and the Shogun, The Dutch Encounter with Tokugawa Japan New York: Columbia University Press 352 pp., $55.00, ISBN 978-0231164283 Publication Date: December 2013 (2015)

"Clulow, Adam The Company and the Shogun, The Dutch Encounter with Tokugawa Japan New York: Columbia University Press 352 pp., $55.00, ISBN 978-0231164283 Publication Date: December 2013." History: Reviews of New Books, 44(1), pp. 24–25
Ablation of Hepatic Production of the Acid-Labile Subunit in Bovine-GH Transgenic Mice: Effects on Organ and Skeletal Growth (2017)

Growth hormone (GH) and insulinlike growth factor 1 (IGF-1) are anabolic hormones that facilitate somatic and skeletal growth and regulate metabolism via endocrine and autocrine/paracrine mechanisms. We hypothesized that excess tissue production of GH would protect skeletal growth and integrity in states of reduction in serum IGF-1 levels. To test our hypothesis, we used bovine GH (bGH) transgenic mice as a model of GH hypersecretion and ablated the liver-derived acid-labile subunit, which stabilizes IGF-1 complexes with IGF-binding protein-3 and -5 in circulation. We used a genetic approach to create bGH/als gene knockout (ALSKO) mice and small interfering RNA (siRNA) gene-silencing approach to reduce als or igf-1 gene expression. We found that in both models, decreased IGF-1 levels in serum were associated with decreased body and skeletal size of the bGH mice. Excess GH produced more robust bones but compromised mechanical properties in male mice. Excess GH production in tissues did not protect from trabecular bone loss in response to reductions in serum IGF-1 (in bGH/ALSKO or bGH mice treated with siRNAs). Reduced serum IGF-1 levels in the bGH mice did not alleviate the hyperinsulinemia and did not resolve liver or kidney pathologies that resulted from GH hypersecretion. We concluded that reduced serum IGF-1 levels decrease somatic and skeletal growth even in states of excess GH.
Molecular basis of ocular abnormalities associated with proximal renal tubular acidosis (2001)

Proximal renal tubular acidosis associated with ocular abnormalities such as band keratopathy, glaucoma, and cataracts is caused by mutations in the Na+-HCO3– cotransporter (NBC-1). However, the mechanism by which NBC-1 inactivation leads to such ocular abnormalities remains to be elucidated. By immunological analysis of human and rat eyes, we demonstrate that both kidney type (kNBC-1) and pancreatic type (pNBC-1) transporters are present in the corneal endothelium, trabecular meshwork, ciliary epithelium, and lens epithelium. In the human lens epithelial (HLE) cells, RT-PCR detected mRNAs of both kNBC-1 and pNBC-1. Although a Na+-HCO3– cotransport activity has not been detected in mammalian lens epithelia, cell pH (pHi) measurements revealed the presence of Cl–-independent, electrogenic Na+-HCO3– cotransport activity in HLE cells. In addition, up to 80% of amiloride-insensitive pHi recovery from acid load in the presence of HCO3–/CO2 was inhibited by adenovirus-mediated transfer of a specific hammerhead ribozyme against NBC-1, consistent with a major role of NBC-1 in overall HCO3– transport by the lens epithelium. These results indicate that the normal transport activity of NBC-1 is indispensable not only for the maintenance of corneal and lenticular transparency but also for the regulation of aqueous humor outflow.