gebhart/patrepeval huggingface dataset:
Morphometric analysis of cellular interactions with the endothelium during the development of arterial lesions using Scanning Electron Microscopy and digital image analysis (1987)

Previous research documenting the chronology of the cellular interactions that occur on or below the surface of the endothelium during the initiation and progression of arterial lesions, primarily consisted of descriptive studies. The recent development of lower cost image analysis hardware and software has facilitated the collection of high resolution quantitative data from microscopic images. In this report we present preliminary quantitative data on the sequence of cellular interactions that occur on the endothelium during the initiation of atherosclerosis or vasculitis utilizing digital analysis of images obtained directly from the scanning electron microscope. Segments of both atherosclerotic and normal arteries were obtained from either diet-induced or endogenously (WHHL) hypercholesterolemic rabbits following 1-4 months duration of hypercholesterolemia and age matched control rabbits. Vasculitis was induced in rats following placement of an endotoxin soaked thread adjacent to the adventitial surface of arteries.
Upgrading Fast Pyrolysis Liquids (2019)

The liquid formed from fast pyrolysis (FP) of biomass is commonly termed bio-oil. The corrosiveness, chemical and thermal instability, viscosity, and high water content of bio-oil require it to be upgraded before it can be used in many applications including transportation fuels. This chapter considers upgrading strategies which include stabilization of bio-oil through low temperature hydroprocessing followed by higher temperature "deep hydrotreating" to remove the most of the remaining oxygen. A major goal of bio-oil upgrading is production of liquid transportation fuels such as gasoline or diesel. Fuels are often considered in terms of the atmospheric boiling range of the fuel mixtures, such as gasoline, and diesel. Commoditization of bio-oil towards a common product as a feedstock for commercial fuel and chemical processes will be greatly facilitated by the development of the common standards and advanced characterization techniques.
The Ubiquitin-Proteasome System Participates in Sperm Surface Subproteome Remodeling during Boar Sperm Capacitation (2023)

Sperm capacitation is a complex process endowing biological and biochemical changes to a spermatozoon for a successful encounter with an oocyte. The present study focused on the role of the ubiquitin-proteasome system (UPS) in the remodeling of the sperm surface subproteome. The sperm surface subproteome from non-capacitated and in vitro capacitated (IVC) porcine spermatozoa, with and without proteasomal inhibition, was selectively isolated. The purified sperm surface subproteome was analyzed using high-resolution, quantitative liquid chromatography-mass spectrometry (LC-MS) in four replicates. We identified 1680 HUGO annotated proteins, out of which we found 91 to be at least 1.5× less abundant (<i>p</i> < 0.05) and 141 to be at least 1.5× more abundant (<i>p</i> < 0.05) on the surface of IVC spermatozoa. These proteins were associated with sperm capacitation, hyperactivation, metabolism, acrosomal exocytosis, and fertilization. Abundances of 14 proteins were found to be significantly different (<i>p</i> < 0.05), exceeding a 1.5-fold abundance between the proteasomally inhibited (100 µM MG132) and vehicle control (0.2% ethanol) groups. The proteins NIF3L1, CSE1L, NDUFB7, PGLS, PPP4C, STK39, and TPRG1L were found to be more abundant; while BPHL, GSN, GSPT1, PFDN4, STYXL1, TIMM10, and UBXN4 were found to be less abundant in proteasomally inhibited IVC spermatozoa. Despite the UPS having a narrow range of targets, it modulated sperm metabolism and binding by regulating susceptible surface proteins. Changes in CSE1L, PFDN4, and STK39 during in vitro capacitation were confirmed using immunocytochemistry, image-based flow cytometry, and Western blotting. The results confirmed the active participation of the UPS in the extensive sperm surface proteome remodeling that occurs during boar sperm capacitation. This work will help us to identify new pharmacological mechanisms to positively or negatively modulate sperm fertilizing ability in food animals and humans.
Radio-over-Fiber Transmission Technology for Future Mobile Access Network toward Beyond-5G Era (2018)

The future mobile access network exploiting Radio-over-Fiber transmission technology is overviewed in this paper. Relating recent achievements are introduced, and future issues to be further investigated are also explained.
A Compact Cold-Atom Interferometer with a High Data-Rate Grating Magneto-Optical Trap and a Photonic-Integrated-Circuit-Compatible Laser System (2021)

The extreme miniaturization of a cold-atom interferometer accelerometer requires the development of novel technologies and architectures for the interferometer subsystems. Here we describe several component technologies and a laser system architecture to enable a path to such miniaturization. We developed a custom, compact titanium vacuum package containing a microfabricated grating chip for a tetrahedral grating magneto-optical trap (GMOT) using a single cooling beam. In addition, we designed a multi-channel photonic-integrated-circuit-compatible laser system implemented with a single seed laser and single sideband modulators in a time-multiplexed manner, reducing the number of optical channels connected to the sensor head. In a compact sensor head containing the vacuum package, sub-Doppler cooling in the GMOT produces 15 uK temperatures, and the GMOT can operate at a 20 Hz data rate. We validated the atomic coherence with Ramsey interferometry using microwave spectroscopy, then demonstrated a light-pulse atom interferometer in a gravimeter configuration for a 10 Hz measurement data rate and T = 0 - 4.5 ms interrogation time, resulting in $Δ$ g / g = 2.0e-6. This work represents a significant step towards deployable cold-atom inertial sensors under large amplitude motional dynamics.
On Channel State Information in Multiple Antenna Block Fading Channels (2000)

Motivated by large capacity gains in multiple antenna systems when perfect channel state information is available at both receiver and transmitter, we examine the achievable rates of channel measurement based techniques. We assume that instantaneous channel state is not known a priori and measured at the receiver and transmitter using part of the total system resources. The receiver side information is obtained using a preamble. For transmitter side information, two classes of feedback channel are studied, a time-division duplex mode and a two-way channel mode. For each class, we study both low-rate quantized and reverse preamble feedback. Lower bounds for achievable rates are derived for the proposed methods, and these bounds are used for resource allocation among the preamble and the feedback. For slowly fading channels, significant gains over non-measurement schemes are possible even with a single bit of feedback.
Disentangled Adversarial Transfer Learning for Physiological Biosignals (2020)

Recent developments in wearable sensors demonstrate promising results for monitoring physiological status in effective and comfortable ways. One major challenge of physiological status assessment is the problem of transfer learning caused by the domain inconsistency of biosignals across users or different recording sessions from the same user. We propose an adversarial inference approach for transfer learning to extract disentangled nuisance-robust representations from physiological biosignal data in stress status level assessment. We exploit the trade-off between task-related features and person-discriminative information by using both an adversary network and a nuisance network to jointly manipulate and disentangle the learned latent representations by the encoder, which are then input to a discriminative classifier. Results on cross-subjects transfer evaluations demonstrate the benefits of the proposed adversarial framework, and thus show its capabilities to adapt to a broader range of subjects. Finally we highlight that our proposed adversarial transfer learning approach is also applicable to other deep feature learning frameworks.
Indirect Nanoplasmonic sensing in catalysis: sintering, reactant surface coverage changes and optical nanocalorimetry (2011)

We report four different application areas, within catalysis, of a new “nanoplasmonic” (localized surface plasmon resonance, LSPR) method, Indirect Nanoplasmonic Sensing (INPS), which uses a remarkably simple optical transmission (or reflection) measurement. The method can with high sensitivity follow catalytic reactions in real time in-situ and can be applied to both model catalysts and real supported catalysts at realistic catalyst working conditions (i.e. high pressures and temperatures).
Small directional microelectromechanical systems microphone arrays (2013)

Directional microphone arrays that are physically small compared to the acoustic wavelength are of great interest for hand-held communication devices. Spatially directive microphones can reduce the impact of background acoustic noise without adding distortion to the signal. This talk will present some design topologies and requirements as well as a new physical design that could enable directional microphone responses while being small in size.
Calixarene Electron Beam Resist for Nano-Lithography (1997)

New electron beam (EB) resists made of calixarene resists are introduced. Typical sensitivities of calixarene resists range from 700 µ C/cm 2 to 7 mC/cm 2 . High-density dot arrays with 15 nm diameter constructed using calixarene resist were easily delineated using a point EB lithography system. Our results suggest that the resolution limit of calixarene resists is dominated by a development process such as adhesion to a substrate rather than by the EB profile. Calixarene resists are resistant to etching by halide plasma. We also demonstrated nanoscale devices processed by using calixarene resists. Calixarene resists are promising materials for nanofabrication.
Electron density and electrostatic potential study of an organic phosphate (2005)

CHARGE, SPIN AND MOMENTUM DENSITY C423 sets. Therefore, there are only two reports of high-resolution magnetic Compton experiments
Spin-labeling proton NMR study on aromatic amino acid residues in the guanine nucleotide binding site of human c-Ha-ras(1-171) protein (1989)

A truncated human c-Ha-ras gene product, ras(1-171) protein, was prepared and chemically modified with maleimide spin-label (MSL). By trypsin digestion of the MSL-labeled ras(1-171) protein, MSL-labeled peptide fragments were isolated and sequenced. The cysteine residue in position 118 of the protein, but not the other cysteine residues, Cys-51 or Cys-80, was found to be specifically labeled by MSL. The ESR spectrum of the MSL-labeled ras(1-171) protein indicates that the MSL group attached to Cys-118 is strongly immobilized. Proton NMR spectra at 400-MHz were measured for this MSL-labeled ras(1-171) protein and also for a control sample of a labeled ras(1-171) protein whose MSL was reduced by sodium ascorbate. In the difference spectra for these two proteins, resonances of protons in the vicinity of the MSL group attached to Cys-118 of the ras(1-171) protein were observed. Thus, the MSL group was found to be in the vicinity of the protein-bound GDP. A phenylalanine residue and two histidine residues, which were characterized by 2D HOHAHA and DQF-COSY spectra, were also found to be in the vicinity of MSL. NOE and pH titration analyses indicate that this phenylalanine residue is close to the bound GDP and one of the two histidine residues. By carboxypeptidase digestion, the two histidine residues near MSL were identified as His-27 and His-94.(ABSTRACT TRUNCATED AT 250 WORDS)
Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS) for on- and off-line analysis of atmospheric gas and aerosol species (2016)

Abstract. Measurement techniques that provide molecular-level information are needed to elucidate the multi-phase processes that produce secondary organic aerosol (SOA) species in the atmosphere. Here we demonstrate the application of ion mobility spectrometry-mass spectrometry (IMS-MS) to the simultaneous characterization of the elemental composition and molecular structures of organic species in the gas and particulate phases. Molecular ions of gas-phase organic species are measured online with IMS-MS after ionization with a custom build nitrate chemical ionization (CI) source. This CI-IMS-MS technique is used to obtain time-resolved measurements (5 min) of highly oxidized organic molecules during the 2013 Southern Oxidant and Aerosol Study (SOAS) ambient field campaign in the forested SE US. The ambient IMS-MS signals are consistent with laboratory IMS-MS spectra obtained from single-component carboxylic acids and multicomponent mixtures of isoprene and monoterpene oxidation products. Mass-mobility correlations in the 2-dimensional IMS-MS space provide a means of identifying ions with similar molecular structures within complex mass spectra and are used to separate and identify monoterpene oxidation products in the ambient data that are produced from different chemical pathways. Water-soluble organic carbon (WSOC) constituents of fine aerosol particles that are not resolvable with standard analytical separation methods, such as liquid chromatography (LC), are shown to be separable with IMS-MS coupled to an electrospray ionization (ESI) source. The capability to use ion mobility to differentiate between isomers is demonstrated for organosulfates derived from the reactive uptake of isomers of isoprene epoxydiols (IEPOX) onto wet acidic sulfate aerosol. Controlled fragmentation of precursor ions by collisional dissociation (CID) in the transfer region between the IMS and the MS is used to validate MS peak assignments, elucidate structures of oligomers, and confirm the presence of the organosulfate functional group.
Supplementary Tables 1-5 from Isolation of T-Cell Receptors Specifically Reactive with Mutated Tumor-Associated Antigens from Tumor-Infiltrating Lymphocytes Based on CD137 Expression (2023)

&lt;p&gt;These tables contain details describing mutations identified by whole exome and RNA sequencing, tandem mini-gene constructs, and HLA peptide binding predictions&lt;/p&gt;
Evaluation methods for creativity support environments (2013)

Creativity refers to the human processes that underpin sublime forms of expression and fuel innovation. Creativity support environments (CSEs) address diverse areas, such as education, science, business, disaster response, design, art, performance, and everyday life. A CSE may consist of a desktop application, or use specialized hardware, networked topologies, and mobile devices. CSEs may address temporal-spatial aspects of collaborative work. This workshop gathers a community of researchers developing and evaluating CSEs. We will share approaches, engage in dialogue, and develop best practices. The outcome is not a single prescription, but an ontology of methodologies with consideration to how they map to creative activities, and an emerging consensus on the range of expectations for rigorous evaluation to shape the field of CSE research. The workshop will organize an open repository of CSE evaluation methods and test data.
The D3 receptor and its relevance in psychiatry (1995)

A large fraction of neurotensin neurons in the ventromedial shell subdivision of nucleus accumbens express D3 receptors. Blockade of D2/D3 receptors by antipsychotic agents paradoxically decreases neurotensin gene expression in these neurons whereas it enhances it in other striatal areas expressing the D2 receptor. This suggests that D2 and D3 receptors mediate opposite actions of dopamine. In support of this view low doses of nafadotride, a novel D3 receptor-preferring antagonist, enhances locomotor activity in rodents, a behavioral response opposite to that of current neuroleptics. The action of D3 receptor-preferring agonists was characterized by the mitogenic response they elicit in transfected NG 108-15 cells. Finally, gene expression of the D3 receptor is in opposition to that of the D2 receptor, being decreased by denervation and unaffected by chronic blockade by neuroleptics.
Tomography of epidermal growth factor receptor binding to fluorescent Affibodyin vivostudied with magnetic resonance guided fluorescence recovery in varying orthotopic glioma sizes (2015)

The ability to image targeted tracer binding to epidermal growth factor receptor (EGFR) was studied in vivo in orthotopically grown glioma tumors of different sizes. The binding potential was quantified using a dual-tracer approach, which employs a fluorescently labeled peptide targeted to EGFR and a reference tracer with similar pharmacokinetic properties but no specific binding, to estimate the relative bound fraction from kinetic compartment modeling. The recovered values of binding potential did not vary significantly as a function of tumor size (1 to 33 mm3), suggesting that binding potential may be consistent in the U251 tumors regardless of size or stage after implantation. However, the fluorescence yield of the targeted fluorescent tracers in the tumor was affected significantly by tumor size, suggesting that dual-tracer imaging helps account for variations in absolute uptake, which plague single-tracer imaging techniques. Ex vivo analysis showed relatively high spatial heterogeneity in each tumor that cannot be resolved by tomographic techniques. Nonetheless, the dual-tracer tomographic technique is a powerful tool for longitudinal bulk estimation of receptor binding.
Binary Sequences Set with Small ISL for MIMO Radar Systems (2018)

In this paper, we aim at designing a set of binary sequences with good aperiodic auto- and crosscorrelation properties for Multiple-Input-Multiple-Output (MIMO) radar systems. We show such a set of sequences can be obtained by minimizing the Integrated Side Lobe (ISL) with the binary requirement imposed as a design constraint. By using the block coordinate descent (BCD) framework, we propose an efficient monotonic algorithm based on Fast Fourier Transform (FFT), to minimize the objective function which is non-convex and NP-hard in general. Simulation results illustrate that the ISL of designed binary set of sequences is the neighborhood of the Welch bound, Indicating its superior performance.
Correction to Coordinative Alignment To Achieve Ordered Guest Molecules in a Versatile Molecular Crystalline Sponge (2018)

ADVERTISEMENT RETURN TO ISSUEPREVAdditions and Correc...Additions and CorrectionsNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Coordinative Alignment To Achieve Ordered Guest Molecules in a Versatile Molecular Crystalline SpongeLe WangLe WangMore by Le Wang, Curtis E. MooreCurtis E. MooreMore by Curtis E. Moore, and Seth M. Cohen*Seth M. CohenMore by Seth M. Cohenhttp://orcid.org/0000-0002-5233-2280Cite this: Cryst. Growth Des. 2018, 18, 4, 2665Publication Date (Web):March 12, 2018Publication History Published online12 March 2018Published inissue 4 April 2018https://pubs.acs.org/doi/10.1021/acs.cgd.8b00359https://doi.org/10.1021/acs.cgd.8b00359correctionACS PublicationsCopyright © 2018 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views701Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (183 KB) Get e-AlertscloseSUBJECTS:Crystals,Molecules Get e-Alerts
Development and validation of a comprehensive synchronous machine model for a real-time environment (2009)

A comprehensive model of a salient-pole synchronous machine is developed for a real-time environment. By obtaining the effective specific permeance of the machine from simple experimental measurements and the exact geometry of the rotor pole-arc, a model is developed that includes the exact distribution of windings and operating-point dependent saturation. This model offers a superior simulated response of the machine for fault transients as well as for steady state harmonic behaviour, and is suitable for the closed-loop testing of relays and controls. The inductances of the machine are computed using the modified winding function approach and validated using finite element analysis. Finally, the performance of the model is validated under healthy and faulted conditions by comparison with tests on an actual machine.
Lateral Control of Indium Content and Wavelength of III–Nitride Diode Lasers by Means of GaN Substrate Patterning (2012)

A patterned GaN/sapphire template with separate regions angled between 0.4 and 2° to the wurtzite c-plane was used to grow a 50 nm In0.1Ga0.9N layer. The photoluminescence wavelength varied between 403 and 389 nm according to the increased region's angle. The indium content measured using X-rays was reduced in regions with a higher miscut angle. Patterned freestanding GaN with separate regions angled by 0.35 and 0.85° to the c-plane was used to fabricate ridge-waveguide diode lasers. Each laser stripe was placed inside one of the angled regions. Lasing wavelengths of 405.8±0.2 and 401.0±1 nm were obtained for devices grown in those regions.
Renal protection from ischemia mediated by A2A adenosine receptors on bone marrow–derived cells (2003)

Activation of A 2A adenosine receptors (A 2A Rs) protects kidneys from ischemia-reperfusion injury (IRI). A 2A Rs are expressed on bone marrow-derived (BM-derived) cells and renal smooth muscle, epithelial, and endothelial cells. To measure the contribution of A 2A Rs on BM-derived cells in suppressing renal IRI, we examined the effects of a selective agonist of A 2A Rs, ATL146e, in chimeric mice in which BM was ablated by lethal radiation and reconstituted with donor BM cells derived from GFP, A 2A R-KO, or WT mice to produce GFPWT, A 2A -KOWT, or WTWT mouse chimera. We found little or no repopulation of renal vascular endothelial cells by donor BM with or without renal IRI. ATL146e had no effect on IRI in A 2A -KO mice or A 2A -KOWT chimera, but reduced the rise in plasma creatinine from IRI by 75% in WT mice and by 60% in WTWT chimera. ATL146e reduced the induction of IL-6, IL-1, IL-1ra, and TGF- mRNA in WTWT mice but not in A 2A -KOWT mice. Plasma creatinine was significantly greater in A 2A -KO than in WT mice after IRI, suggesting some renal protection by endogenous adenosine. We conclude that protection from renal IRI by A 2A R agonists or endogenous adenosine requires activation of receptors expressed on BM-derived cells.
Issues in boundary control [of power convertors] (2002)

State plane analysis is used to study large-signal properties and control strategies for DC-DC power converters. A general load line is defined and interpreted. The concept of a switching boundary is convenient for generalizing hysteretic controls. Boundaries are classified according to their local dynamics. Requirements for large-signal stability are established. It is shown that stable boundary controllers always require frequency limits or timing constraints to avoid chattering. Limit cycles occur under certain conditions when discontinuous mode adds a second boundary.