gebhart/patrepeval huggingface dataset:
Transformer design to achieve soft switching in low power Flyback converters (2016)

Soft switching in DC-DC converters is a well accepted technique and its advantages are widely discussed. Undoubtedly, the soft switching reduces the power loss in the Main switch while improving the overall EMI in the converters. This facilitates the increase of switching frequency of converters. This paper highlights a design methodology for the transformer in a fly back converter, which automatically accomplishes the complete soft switching of the main switch. No extra circuit or the control scheme is needed to attain Zero Current Turn On and total Zero Voltage Switching (both during turn ON and Turn OFF) of the Main MOSFET switch. Also, it eliminates the Dissipative snubber which is an essential component in fly back converter. However, this scheme is wholly applicable to fixed Input and constant load applications. Nevertheless, most of the Industry scenarios are similar at low power range of about 50 to 100 watts, because invariably the DC-DC converters are operated from a Power factor correction module (Whose output is fairly regulated to around 400V DC) and the output load is constant. The design concept is demonstrated on a 60 watt fly back converter operating from a 400V DC bus and operated at 100 KHz.
Joint PELS\/IAS\/IES New South Wales Chapter Hosts Distinguished Lecturers [Society News] (2018)

The Joint IEEE Power Electronics Society, Industry Applications Society, and Industrial Electronics Society (PELS/IAS/IES) New South Wales Chapter kicked off 2018 with two Distinguished Lectures. Prof. Udaya Madawala, on behalf of PELS, gave the first lecture "Grid Integration of Electric Vehicles," and Prof. Xinghuo Yu, representing IAS, gave the second lecture, "Smart Grid and Beyond" (Figure 1).
Compressive Phase Retrieval via Reweighted Amplitude Flow (2018)

The problem of reconstructing a sparse signal vector from magnitude-only measurements (a.k.a. compressive phase retrieval) emerges in diverse applications, but it is NP-hard in general. Building on recent advances in nonconvex optimization, this paper puts forth a new algorithm that is termed compressive reweighted amplitude flow (CRAF) and abbreviated as CRAF, for compressive phase retrieval. Specifically, CRAF operates in two stages. The first stage seeks a sparse initial guess via a new spectral procedure. In the second stage, CRAF implements a few hard thresholding based iterations using reweighted gradients. When there are sufficient measurements, CRAF provably recovers the underlying signal vector exactly with high probability under suitable conditions. Moreover, its sample complexity coincides with that of state-of-the-art procedures. Finally, numerical tests showcase improved performance of the new spectral initialization, as well as improved exact recovery relative to competing alternatives. Empirically, the number of measurements required for exact recovery by CRAF is about 40% less than those of competing alternatives in our experiments using real images.
A new method for calculating the resonant frequency of multisegment dielectric resonator antennas (2003)

This paper introduces a new method based on dielectric waveguide model (DWM) for predicting the resonant frequency of multisegment dielectric resonator antennas (MSDRAs). In this method assumed that the influence of each segment in the resonant frequency of the whole structure is proportional to its height. The results of the proposed method are compared with the previous method and experimental results. The method yields more accurate resonant frequencies than the previous method. The results are also checked with HPHFSS.
24‐hour intraocular pressure rhythm in young healthy subjects evaluated with continuous monitoring using contact lens sensor (2013)

Abstract Purpose To evaluate 24‐h intraocular pressure (IOP) rhythm reproducibility during repeated continuous 24‐h IOP monitoring with non‐contact tonometry (NCT) and a contact lens sensor (CLS) in healthy subjects. Methods Twelve young healthy subjects were housed in a sleep laboratory and underwent four 24‐h sessions of IOP measurements over a 6‐month period. After randomized attribution, the IOP of the ﬁrst eye was continuously monitored using the CLS Sensimed TriggerFish® and the IOP of the fellow eye was measured hourly using the Pulsair Intellipuﬀ® non‐contact tonometer. A nonlinear least‐squares dual harmonic regression analysis was used to model the 24‐h IOP rhythm. Comparison of acrophase, bathyphase, amplitude, the midline estimating statistic of rhythm (MESOR), IOP values, IOP changes and agreement were evaluated in the two tonometry methods. Results A significant nyctohemeral IOP rhythm was found in 31 out of 36 sessions (86%) using NCT and in all sessions (100%) using CLS. Hourly awakening during NCT IOP measurements did not significantly change the mean phases of the 24‐h IOP pattern evaluated using CLS in the contralateral eye. Throughout the sessions, intraclass correlation coefficients (ICCs) of the CLS acrophase (0.6 [0–0.9]; p=0.03), CLS bathyphase (0.7 [0.1–0.9]; p=0.01), NCT amplitude (0.7 [0.1–0.9]; p=0.01) and NCT MESOR (0.9 [0.9–1]; p&lt;0.01) were significant. Conclusion The CLS is an accurate and reproducible method to characterize the nyctohemeral IOP rhythm in healthy subjects but does not allow to estimate the IOP value in millimeters of mercury corresponding to the relative variation of the electrical signal measured.
Inducing Humoral and Cellular Responses to Multiple Sporozoite and Liver-Stage Malaria Antigens Using Exogenous Plasmid DNA (2013)

A vaccine candidate that elicits humoral and cellular responses to multiple sporozoite and liver-stage antigens may be able to confer protection against Plasmodium falciparum malaria; however, a technology for formulating and delivering such a vaccine has remained elusive. Here, we report the preclinical assessment of an optimized DNA vaccine approach that targets four P. falciparum antigens: circumsporozoite protein (CSP), liver stage antigen 1 (LSA1), thrombospondin-related anonymous protein (TRAP), and cell-traversal protein for ookinetes and sporozoites (CelTOS). Synthetic DNA sequences were designed for each antigen with modifications to improve expression and were delivered using in vivo electroporation (EP). Immunogenicity was evaluated in mice and nonhuman primates (NHPs) and assessed by enzyme-linked immunosorbent assay (ELISA), gamma interferon (IFN-γ) enzyme-linked immunosorbent spot (ELISpot) assay, and flow cytometry. In mice, DNA with EP delivery induced antigen-specific IFN-γ production, as measured by ELISpot assay and IgG seroconversion against all antigens. Sustained production of IFN-γ, interleukin-2, and tumor necrosis factor alpha was elicited in both the CD4(+) and CD8(+) T cell compartments. Furthermore, hepatic CD8(+) lymphocytes produced LSA1-specific IFN-γ. The immune responses conferred to mice by this approach translated to the NHP model, which showed cellular responses by ELISpot assay and intracellular cytokine staining. Notably, antigen-specific CD8(+) granzyme B(+) T cells were observed in NHPs. Collectively, the data demonstrate that delivery of gene sequences by DNA/EP encoding malaria parasite antigens is immunogenic in animal models and can harness both the humoral and cellular arms of the immune system.
Techno-Economic Analysis of Lithium-Ion Batteries for Personal Vehicle Electrification (2011)

Better design and integration of lithium-ion batteries can help lower costs of plug-in hybrid electric vehicles (PHEVs) and battery electric vehicles (BEVs). The form factor of the electrode is an important design variable that directly relates to the usable power density of the cell and also affects the cost. This work, currently in progress, looks at performing sensitivity analyses on the effects of varying the electrode thicknesses of lithium-ion batteries for different electrified vehicles (EVs, plug-ins of different all-electric-ranges and battery electric vehicles) based on their power and energy density requirements, with the overall cost of production of the batteries for that EV application as a key output parameter. This is being done using the software Battery Design Studio. It will thereby estimate and identify the least cost battery packs for any EV application, which will be of use to automakers. Policy makers can also relate to this study while incentivizing different battery pack designs and sizes, which will ensure that lithium-ion batteries are more economically and usefully implemented.
Supplementary Figure 7 from Canonical Wnt Signaling Is Required for Pancreatic Carcinogenesis (2023)

&lt;p&gt;PDF file - 6752K, Supplemental Figure 7. Inhibition of Wnt/β-catenin signaling by Dkk1 reduces epithelial cell proliferation.&lt;/p&gt;
Molecular structure and magnetic properties of the chloro-bridged dimer chloro[hydrotris(1-pyrazolyl)borato]copper(II). Observation of a ferromagnetic ground state (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMolecular structure and magnetic properties of the chloro-bridged dimer chloro[hydrotris(1-pyrazolyl)borato]copper(II). Observation of a ferromagnetic ground stateStephanie G. N. Roundhill, D. Max Roundhill, Darrel R. Bloomquist, Christopher Landee, Roger D. Willett, David M. Dooley, and Harry B. GrayCite this: Inorg. Chem. 1979, 18, 3, 831–835Publication Date (Print):March 1, 1979Publication History Published online1 May 2002Published inissue 1 March 1979https://pubs.acs.org/doi/10.1021/ic50193a059https://doi.org/10.1021/ic50193a059research-articleACS PublicationsRequest reuse permissionsArticle Views358Altmetric-Citations88LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
SK3 K+ channel‐deficient mice have enhanced dopamine and serotonin release and altered emotional behaviors (2008)

SK3 K(+) channels influence neuronal excitability and are present in 5-hydroxytryptamine (5-HT) and dopamine (DA) nuclei in the brain stem. We therefore hypothesized that SK3 channels affect 5-HT and DA neurotransmission and associated behaviors. To explore this, we used doxycycline-induced conditional SK3-deficient (T/T) mice. In microdialysis, T/T mice had elevated baseline levels of striatal extracellular DA and the metabolites dihydroxyphenylacetic acid and homovanillic acid. While baseline hippocampal extracellular 5-HT was unchanged in T/T mice, the 5-HT response to the 5-HT transporter inhibitor citalopram was enhanced. Furthermore, baseline levels of the 5-HT metabolite 5-hydroxyindoleacetic acid were elevated in T/T mice. T/T mice performed equally to wild type (WT) in most sensory and motor tests, indicating that SK3 deficiency does not lead to gross impairments. In the forced swim and tail suspension tests, the T/T mice displayed reduced immobility compared with WT, indicative of an antidepressant-like phenotype. Female T/T mice were more anxious in the zero maze. In contrast, anxiety-like behaviors in the open-field and four-plate tests were unchanged in T/T mice of both sexes. Home cage diurnal activity was also unchanged in T/T mice. However, SK3 deficiency had a complex effect on activity responses to novelty: T/T mice showed decreased, increased or unchanged activity responses to novelty, depending on sex and context. In summary, we report that SK3 deficiency leads to enhanced DA and 5-HT neurotransmission accompanied by distinct alterations in emotional behaviors.
Beaconless adaptive-optics technique for HEL beam control (2016)

Effective performance of forthcoming laser systems capable of power delivery on a distant target requires an adaptive optics system to correct atmospheric perturbations on the laser beam. The turbulence-induced effects are responsible for beam wobbling, wandering, and intensity scintillation, resulting in degradation of the beam quality and power density on the target. Adaptive optics methods are used to compensate for these negative effects. In its turn, operation of the AOS system requires a reference wave that can be generated by the beacon on the target. This report discusses a beaconless approach for wavefront correction with its performance based on the detection of the target-scattered light. Postprocessing of the beacon-generated light field enables retrieval and detailed characterization of the turbulence-perturbed wavefront –data that is essential to control the adaptive optics module of a high-power laser system.
Orientation of embedded Y 2 BaCuO 5 particles within the YBa 2 Cu 3 O x matrix in melt‐textured YBCO superconductors (2005)

Automated electron backscatter diffraction (EBSD) was employed to study the local orientations of embedded Y2BaCuO5 (Y-211) particles within the YBa2Cu3Ox (Y-123) superconducting matrix of large grain, melt-textured Y-Ba-Cu-O (YBCO) samples. High-quality Kikuchi patterns were obtained, enabling automated mapping of the individual crystal orientations and a two-phase analysis of the samples. Investigations were performed on a variety of melt-textured YBCO samples, including samples with different element additions. We observe from the maps that the embedded Y-211 particles do not have any preferred orientation in melt-textured YBCO with (001) orientation, and that the YBCO growth is not altered for certain orientations of the Y-211 particles. In samples with (100) orientation, on the other hand, we observe only a small misorientation within the YBCO matrix, and the embedded Y-211 particles do not exhibit any texture. We can conclude from the EBSD maps obtained that the formation of small Y-211 particles does not disturb the Y-123 matrix growth, whereas the presence of large Y-211 particles leads, significantly, to the formation of subgrains. (© 2005 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
Economies of Scale, Natural Monopoly, and Imperfect Competition in an Experimental Market (1994)

Charles R. Plott, Alexandre Borges Sugiyama, Gilad Elbaz, Economies of Scale, Natural Monopoly, and Imperfect Competition in an Experimental Market, Southern Economic Journal, Vol. 61, No. 2 (Oct., 1994), pp. 261-287
Heat Transfer in a Drilling Fluid with Geothermal Applications (2017)

The effects of various conditions on the fluid flow, particle migration and heat transfer in non-linear fluids encountered in drilling and geothermal applications are studied. We assume that the drilling fluid is a suspension composed of various substances, behaving as a non-linear complex fluid, where the effects of particle volume fraction, shear rate, and temperature on the viscosity and thermal diffusivity are considered. The motion of the particles is described using a concentration flux equation. Two problems are studied: flow in a vertical pipe and flow between two (eccentric) cylinders where the inner cylinder is rotating. We consider effects of earth temperature, the rotational speed of the inner cylinder, and the bulk volume fraction on the flow and heat transfer.
Channel Models for the Simulation of Different RATs Applied to Platoon Emergency Braking (2019)

We analyze the performance of different channel models and Radio Access Technologies (RATs) for platoon emergency braking in a highway scenario. We present a ray tracing channel model and analyze its differences with the WINNER+ stochastic channel model in terms of the pathloss calculation. Thanks to the consideration of obstacles and their reflections, the ray tracing channel model has been shown to be more realistic in near Tx-Rx distance. This corroborates the results of our performance comparison which highlights larger differences in close Tx-Rx pairs. Considering the simulation time consumption and the more realistic ray tracing predictions, we propose a new models usage for our simulations: a combination of WINNER+ and ray tracing channel models. Moreover, we implement one new 5G numerology on the basis of Long Term Evolution-Vehicles (LTE-V) for Vehicle-to-everything (V2X) communications. We include this new feature in our benchmarking setup and provide performance analysis results. It provides a basis for our future research of further 5G components.
Signatures of Bulk and Surface Arsenic Antisite Defects in GaAs(110) (1995)

Scanning tunneling microscopy (STM) has recently been used in the study of bulk arsenic antisite defects in GaAs. In this work, we report extensive theoretical calculations of such defects in the vicinity of a GaAs(110) surface, which provide essential information for the interpretation of experiments. Defects display remarkably distinct properties depending on whether they are fourfold or threefold coordinated. The nature of ``satellite peaks'' observed in experiment is elucidated. We predict the conditions under which STM-measured properties will be faithful to the properties of the bulk defect.
Simultaneous fluorescence and phase imaging with extensions toward sub-diffraction resolution via structured-illumination(Conference Presentation) (2016)

In the biological sciences, there is much emphasis on elucidating the functions of various biological components and processes. To do so, advances in general microscopy have yielded various imaging modalities to probe such processes under specific visualization and contrast requirements. Examples of modalities that are popularly integrated into conventional biological studies include fluorescent, dark-field, phase-contrast, and polarization-sensitive microscopies, with each modality offering unique insights into the biological function of the sample. Often times, however, a comprehensive understanding of biological phenomena requires the integration of the unique and separate visualizations of various modalities. Unfortunately, conventional microscopes typically support only one modality and rarely allow multiple modalities to be used in conjunction. Though high-end microscopes may support multimodal visualization, they often require either mechanical (and often manual) toggling, which obstruct real-time multimodal imaging, or simultaneous detection via multiple cameras, which dramatically increases the microscope’s cost. Here, we present a one-shot technique that allows multiple imaging channels, of potentially different modalities, to be simultaneously detected by a single camera. We experimentally demonstrate this method on transparent cells that have been tagged for F-actin and nuclear fluorescence. Our multimodal system consists of 2-channel fluorescence and 1-channel quantitative-phase (QP) imaging, and clearly demonstrates ability for simultaneous fluorescent and QP visualization. Though we experimentally verify our framework using dual fluorescent/QP imaging, we emphasize that our framework for single-shot, simultaneous single-camera detection is applicable to an arbitrary number of widefield imaging modalities so long as they fulfill criteria for Fourier spectra separation, SNR, and detector dynamic range
On Equivalence Partitioning of Code Paths inside OS Kernel Components (2009)

Commercial-off-the-shelf operating systems (COTS OSs) are increasingly chosen as key building blocks in embedded system design due to their rich feature-set available at low costs. Unfortunately, as the complexity of such OSs increases, testing key OS components such as device drivers (DD) to ensure continuous service provision becomes increasingly challenging. Despite the improving test efforts targeting DDs, they still represent a significant cause of system outages as the test coverage is invariably limited by the inability to exhaustively assess and cover the operational states. Consequently, if representative operational execution profiles of DDs within an OS could be obtained, these could significantly improve the understanding of the actual operational DD state space and help focus the test efforts onto the execution hotspots. Focusing on characterizing DD operational activities while assuming no access to source code, our work enables profiling the runtime behavior of DDs solely based on I/Oand functional-call tracking. Such profiles are used to improve test adequacy against real-world workloads by enabling similarity quantification across them. The profiles also reveal execution hotspots in terms of functionalities activated in the field, allowing for dedicated test campaigns.
Spatially continuous sensing of fiber curvature over sub millimeter lengths with a twisted multicore optical fiber (2021)

Using a twisted multicore optical fiber, we demonstrate the detection of distributed fiber curvature on a textured surface exhibiting a sinusoidal profile with a micron-scale amplitude and a sub-millimeter spatial period.
Synthesis of (±)-10,10-dimethylhuperzine A — a huperzine analogue possessing a slower enzyme off-rate (1996)

The synthesis of (±)-10,10-dimethylhuperzine A is reported together with its kinetic (kon and koff) and dissociation constants for the inhibition of fetal bovine serum acetylcholinesterase. While somewhat more potent than (±)-hyperzine A, the dimethyl analogue shows a slower off-rate from AChE, a result that may be of potential therapeutic value.
Application and Evaluation of a Measured Spatially Variant System Model for PET Image Reconstruction (2010)

Accurate system modeling in tomographic image reconstruction has been shown to reduce the spatial variance of resolution and improve quantitative accuracy. System modeling can be improved through analytic calculations, Monte Carlo simulations, and physical measurements. The purpose of this work is to improve clinical fully-3-D reconstruction without substantially increasing computation time. We present a practical method for measuring the detector blurring component of a whole-body positron emission tomography (PET) system to form an approximate system model for use with fully-3-D reconstruction. We employ Monte Carlo simulations to show that a non-collimated point source is acceptable for modeling the radial blurring present in a PET tomograph and we justify the use of a Na22 point source for collecting these measurements. We measure the system response on a whole-body scanner, simplify it to a 2-D function, and incorporate a parameterized version of this response into a modified fully-3-D OSEM algorithm. Empirical testing of the signal versus noise benefits reveal roughly a 15% improvement in spatial resolution and 10% improvement in contrast at matched image noise levels. Convergence analysis demonstrates improved resolution and contrast versus noise properties can be achieved with the proposed method with similar computation time as the conventional approach. Comparison of the measured spatially variant and invariant reconstruction revealed similar performance with conventional image metrics. Edge artifacts, which are a common artifact of resolution-modeled reconstruction methods, were less apparent in the spatially variant method than in the invariant method. With the proposed and other resolution-modeled reconstruction methods, edge artifacts need to be studied in more detail to determine the optimal tradeoff of resolution/contrast enhancement and edge fidelity.