gebhart/patrepeval huggingface dataset:
Surface Functionalization by High‐precision Laser Cladding (2013)

Abstract Meanwhile the laser build‐up welding technology is a well industrially established technique for highly precise coating tasks and additive manufacturing. By means of new precise powder nozzle systems, modified process equipment as well as suited manufacturing strategies, the generation of customized components can be realized up to a detail resolution within the double‐digit micrometer range. This opens a variety of new applications, e. g. in aviation, tooling industry or medical technology.
ChemInform Abstract: A Method for the Asymmetric Hydrosilylation of N‐Aryl Imines. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Inhaled nitric oxide: diameter response patterns in feline small pulmonary arteries and veins (1996)

Using an X-ray television system on the in vivo cat lung, we directly measured internal diameter (ID) changes in the small pulmonary arteries and veins (100-1,100 microns ID) in response to 5, 15, and 40 ppm nitric oxide (NO) inhalations. We also measured to what extent 40 ppm NO inhalation can attenuate large ID constrictions at the different serial segments of the small vessels due to unilobar anoxic (0% O2) exposure. Under normoxic conditions, 5-40 ppm NO inhalations significantly increased the ID of both arteries and veins less than approximately 900 microns dose dependently but caused no significant, or only slight, ID increases in the vessels larger than this, if any at all. The ID increase in the serially connected arteries was nonuniform (4-18, 8-28, and 7-35% with 5, 15, and 40 ppm NO inhalations, respectively), whereas that for the veins was relatively uniform (4-9, 6-17, and 7-18% with 5, 15, and 40 ppm NO, respectively). The maximum ID increase occurred in the 200- to 500- and 200- to 700-microns arteries in response to 5-15 and 40 ppm NO, respectively. Unilobar anoxic exposure significantly decreased the ID of the 100- to 700-microns arteries and veins, but not the ID of the other-sized vessels. The ID decrease in the serially connected arteries was nonuniform (13-29%) but relatively uniform in the veins (8-12%). The maximum ID decrease occurred in the 200- to 300-microns arteries. However, adding 40 ppm NO to the lobe completely eradicated the ID decreases at all segments of the arteries and veins and, instead, caused significant ID increase (11-21%) in the arteries and (10-12%) in the veins. The data indicate that, according to dosage, 5-40 ppm NO inhalations cause selective dilation of approximately 100- to 900-microns pulmonary arteries and veins, particularly the 200- to 700-microns arteries. During anoxic exposure, the vasodilator effect of NO is preserved and can completely reverse the marked pulmonary vasoconstriction.
Membrane topology and site‐specific mutagenesis of Pseudomonas aeruginosa porin OprD (1995)

Pseudomonas aeruginosa OprD is a 420-amino-acid protein that facilitates the uptake of basic amino acids, imipenem and gluconate across the outer membrane. OprD was the first specific porin that could be aligned with members of the non-specific porin super-family. Utilizing multiple alignments in conjugation with structure predictions and amphipathicity calculations, an OprD-topology model was proposed. Sixteen beta-strands were predicted, connected by short loops at the periplasmic side. The eight external loops were of variable length but tended to be much longer than the periplasmic ones. Polymerase chain reaction (PCR)-based site-specific mutagenesis was performed to delete separately short stretches (4-8 amino acid residues) from each of the predicted external loops. The mutants with deletions in the predicted external loops L1, L2, L5, L6, L7 and L8 were tolerated in both Escherichia coli and P. aeruginosa. The expressed mutant proteins maintained substantial resistance to trypsin treatment in the context of isolated outer membranes. Proteins with deletions in loops L1, L5, L6, L7 and L8 reconstituted similar imipenem supersusceptibility in a P. aeruginosa OprD:: omega background. The L2-deletion mutant only partially reconstituted super-susceptibility, suggesting that loop L2 is involved in imipenem binding. These data were generally consistent with the topology model.
Design of an Integrated Cotton Picking System for Small-Scale Indian Agriculture (2017)

India, the world’s largest producer of cotton, contains more than 4 million cotton farms that are less than 5 acres. These farms are incapable of large-scale mechanization due to small farm size and irregular farm shape. A previous team developed a handheld, roller-based picking device that demonstrated increased performance over similar products. However, a significant improvement in productivity requires increasing picking speed through mechanization as well as increasing worker cotton carrying capacity. We present a system that utilizes the roller-based picking device in tandem with a compressive storage bag and an efficient carrier. Through modeling and initial testing, the system demonstrates a two times (2X) improvement in worker productivity over current methods. This paper characterizes the cotton picking process, details the modules of the integrated system, and suggests further procedural improvements for greater increases in worker productivity.
Motion Planning and Control of a Tractor With a Steerable Trailer Using Differential Flatness (2008)

This paper presents a methodology for trajectory planning and tracking control of a tractor with a steerable trailer based on the system’s dynamic model. The theory of differential flatness is used as the basic approach in these developments. Flat outputs are found that linearize the system’s dynamic model using dynamic feedback linearization, a subclass of differential flatness. It is demonstrated that this property considerably simplifies motion planning and the development of controller. Simulation results are presented in the paper, which show that the developed controller has the desirable performance with exponential stability.
Dysregulation of objectively assessed 24-hour motor activity patterns as a potential marker for bipolar I disorder: results of a community-based family study (2017)

There has been a growing number of studies that have employed actigraphy to investigate differences in motor activity in mood disorders. In general, these studies have shown that people with bipolar disorders (BPDs) tend to exhibit greater variability and less daytime motor activity than controls. The goal of this study was to examine whether patterns of motor activity differ in euthymic individuals across the full range of mood disorder subtypes (Bipolar I (BPI), Bipolar II (BPII) and major depression (MDD)) compared with unaffected controls in a community-based family study of mood spectrum disorders. Minute-to-minute activity counts derived from actigraphy were collected over a 2-week period for each participant. Prospective assessments of the level, timing and day-to-day variability of physical activity measures were compared across diagnostic groups after controlling for a comprehensive list of potential confounding factors. After adjusting for the effects of age, sex, body mass index (BMI) and medication use, the BPI group had lower median activity intensity levels across the second half of the day and greater variability in the afternoon compared with controls. Those with a history of BPII had increased variability during the night time compared with controls, indicating poorer sleep quality. No differences were found in the average intensity, variability or timing of activity in comparisons between other mood disorder subgroups and controls. Findings confirm evidence from previous studies that BPI may be a manifestation of a rhythm disturbance that is most prominent during the second half of the day. The present study is the largest study to date that included the full range of mood disorder subgroups in a nonclinical sample that increases the generalizability of our findings to the general community. The manifestations of activity patterns outside of acute episodes add to the accumulating evidence that dysregulation of patterns of activity may constitute a potential biomarker for BPD.
Effect of Alkyl Derivatization on Several Properties of N-Halamine Antimicrobial Siloxane Coatings (2008)

Variation of alkyl substitution at position 5 on the hydantoin ring of a series of N-halamine siloxane derivatives has been employed to better understand the biocidal activities of these compounds for use in preparing antimicrobial coatings. The alkyl derivatization of the hydantoin ring at its 5 position, while an essentially constant chlorine loading is maintained at the 1 position, has shown that there is little dependence of the antimicrobial efficacy against Escherichia coli O157:H7 on the alkyl chain length, in contrast to reported observations for biocidal quaternary ammonium salt derivatives. The stabilities of the derivatives toward hydrolyses and ultraviolet light exposure have also been found to not be dependent upon the nature of the alkyl substituent group. These observations led to the conclusion that the 5,5-dimethyl derivative would be recommended for use, since it is the least expensive alternative.
Surface Seismic While Drilling - Imaging of Well Bores in Seismic Context (2017)

Summary Conventional methods for positioning of the well bore during drilling are based on using down hole logging. Measurements from these tools are used to compute the well path. To get an understanding of where the well is in the subsurface the well path is projected onto the seismic image from the particular area. This procedure is, in general, problematic as there are uncertainties in the measurements, the seismic image and methods, and differences in accuracy between the methods in use. The surface seismic while drilling (SSWD) method is a new method that uses surface seismic to image well paths. The advantage of SSWD is that no down hole tools are needed to image the well. There is also no need for stopping the drilling operations to image the well. We discuss the SSWD and conventional methods for well bore positioning and show examples on how the SSWD method is used to home-in a relief well to stop a blowing well.
Binding of a nuclear factor to the upstream region of the c-myc gene. (1991)

We have studied the binding of proteins to a synthetic DNA fragment corresponding to a 21 base pair sequence in the upstream region of the human c-myc gene. This sequence has previously been reported to bind the c-myc protein, thus representing a putative site for autoregulation of the c-myc gene (Ariga et al., 1989). Our electrophoretic mobility shift assays indicated that this DNA fragment binds to a factor present in nuclear extracts from HeLa cells. However, analysis of extracts from other cells indicated that this binding does not correlate with the presence of the c-myc protein. No binding was observed using c-myc protein translated in vitro. Also, anti-c-myc antibodies could not inhibit binding of this factor. These experiments indicate, that nucleotides -2193 to -2173 from the P1 promoter of the c-myc gene are able to bind a nuclear factor, and that this factor most likely does not include the c-myc protein.
Pair Monitoring of Redundant Technical Systems (2020)

We pose and solve the deterministic problem of simultaneous technical condition monitoring in real time for both the main (functional) and control (monitoring) parts of the system. We propose an approach based on a logical analysis of the results of the built-in control for a pair of comparable technical devices, which are in the general case heterogeneous in their manufacturing and infrastructural support. We obtain the structure and rules for the construction of the indicator matrix that allows to divide technical devices into fully or partially operational and faulty. We give explicit expressions for the probabilities of fault detection in both parts of the system and for error probabilities of the first and second kind. We also show illustrative examples.
Polyoxometalates as Homogeneous Oxidation Catalysts (2012)

This chapter contains sections titled: Soluble Metal Oxides as Oxidation Catalysts Homogeneous Oxidations with POMs Based Only on Mo(VI), W(VI), V(V) Addenda Ions Homogeneous Oxidations with TMS-POMs Conclusions Acknowledgments References
NEW MATERILS AND MULTIDIMENSIONAL CLUSTER ANALYSIS FOR SAW CHEMICAL SENSOR ARRAYS (1994)

We use six-element arrays of 97-MHz ST-quartz surface acoustic wave (SAW) devices to detect changes in thin-film mass and mechanical properties resulting from sorption of analytes by films representing two new classes of chemical sensor interface: self-assembled monolayers (SAMs) and plasma-grafted films (PGFs). While these materials do not display exceptional chemical selectivity, various combinations of the 7 different SAMs and 8 PGFs examined to produce distinct response patterns for each of 13 analytes. The analytes include aliphatic, aromatic, and chlorinated hydrocarbons; alcohols; ketones; organophosphonates; and water. Evaluation of the SAW array data using multidimensional cluster analysis techniques show that each chemical species can be correctly identified 100% of the time over the 9%- to 49%-of-saturation range using data from many combinations of four or more films.
Evaluation of Modular Integrated Electric Drive Concepts for Automotive Traction Applications (2017)

In order to achieve compactness and realize a certain level of fault tolerance in integrated motor drives, a number of integrated modular motor drive concepts have been proposed in recent years. In this paper, converter topology candidates suitable for an IMMD are considered with particular focus on the stacked polyphase bridges cconverter; the parallel-connected polyphase bridges converter, and the modular high frequency converter. A comparative evaluation of the studied topologies is presented and discussed in terms of machine design aspects, power losses, capacitor energy storage requirements, costs, and cell redundancy using the conventional two-level three-phase drive system as reference.
Establishment of Novel Biosynthetic Pathways for the Production of Salicyl Alcohol and Gentisyl Alcohol in Engineered Escherichia coli (2018)

Salicyl alcohol and gentisyl alcohol are two important phenolic alcohols that possess significant biological activities and pharmaceutical properties. Here, we report establishment of novel biosynthetic pathways for microbial production of salicyl alcohol and gentisyl alcohol from renewable feedstocks. We first examined the promiscuity of the carboxylic acid reductase CAR toward salicylic acid and 2,5-DHBA, which enabled efficient synthesis of salicyl alcohol and gentisyl alcohol. Then, we employed a novel salicylic acid 5-hydroxylase to achieve 2,5-DHBA production from salicylic acid. After that, the de novo biosynthetic pathways were assembled and optimized by programming the carbon flux into the shikimate pathway. The final titers of salicyl alcohol and gentisyl alcohol reached to 594.4 mg/L and 30.1 mg/L, respectively. To our knowledge, this work achieved microbial production of salicyl alcohol and gentisyl alcohol for the first time. Our present study also demonstrated application of enzyme promiscuity to establish non-natural biosynthetic pathways for the production of high-value compounds.
Control of Crystallographic Orientation and Grain Refinement in Bi<sub>2</sub>Te<sub>3</sub>-Based Thermoelectric Semiconductors by Applying High Pressure Torsion (2008)

Prepared were p-type Bi2Te3-based thermoelectric semiconductors, having a grain-refined microstructure and a preferred orientation of anisotropic crystallographic structure. Disks with a nominal composition Bi0.5Sb1.5Te3.0 were cut from an ingot grown by the vertical Bridgman method (VBM) and deformed at 473 K under a pressure of 6.0 GPa by high pressure torsion (HPT). The crystal orientation was characterized with X-ray diffraction. The microstructures were characterized by using optical microscopy and scanning electron microscopy. It was found that the HPT disks had a fine and preferentially oriented grain compared to that of the VBM disks. Further, the power factor of the HPT disks was about twice as large as that of the VBM disks. These results indicate that HPT is effective for improving the thermoelectric properties of Bi2Te3-based thermoelectric semiconductors.
Development of vaccinesagainst Helicobacter pylori (2009)

Helicobacter pylori is a Gram-negative, microaerophilic bacterium adapted to survive in the stomach of humans where it can cause peptide ulcers and gastric cancer. Although effective antibiotic treatment exists, there is a consensus that vaccines are necessary to limit the severity of this infection. Great progress has been made since its discovery 25 years ago in understanding the virulence factors and several aspects of the pathogenesis of the H. pylori gastric diseases. Several key bacterial factors have been identified: urease, vacuolating cytotoxin, cytotoxin-associated antigen, the pathogenicity island, neutrophil-activating protein, and among others. These proteins, in their native or recombinant forms, have been shown to confer protection against infectious challenge with H. pylori in experimental animal models. It is not known, however, through which effector mechanisms this protection is achieved. Nevertheless, a number of clinical trials in healthy volunteers have been conducted using urease given orally as a soluble protein or expressed in bacterial vectors with limited results. Recently, a mixture of H. pylori antigens was reported to be highly immunogenic in H. pylori-negative volunteers following intramuscular administration of the vaccine with aluminium hydroxide as an adjuvant. These data show that vaccination against this pathogen is feasible. More research is required to understand the immunological mechanisms underlying immune-mediate protection.
A Wideband Low-Power RF-to-BB Current-Reuse Receiver Using an Active Inductor and 1 /f Noise-Cancellation for L-Band Applications (2022)

A low-power and wideband RF-to-baseband (BB) current-reuse receiver (CRR) front-end utilizing both a <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$1/f$ </tex-math></inline-formula> noise cancellation (NC) technique and an active inductor (AI) is proposed tuned to operate from 1 GHz to 1.7 GHz for L-Band applications, including those that require high modulation bandwidths. The CRR front-end employs a single supply and shares the bias current of the low noise transconductance amplifier (LNTA) with the BB circuits to reduce the power consumption. To minimize the losses of the radio frequency (RF) signal right before down-conversion, a high impedance AI circuit isolates the mixer input from the CRR output node. The <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$1/f$ </tex-math></inline-formula> NC circuit suppresses the low frequency noise of the LNTA that leaks to the output. A common-gate LNTA with <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\mathrm {g_{m}}$ </tex-math></inline-formula> -boosting, along with a single-to-differential LC-balun are used to enhance the input matching, conversion gain and noise figure (NF). The proposed receiver is fabricated in a TSMC 130 nm CMOS process and occupies an active area of 0.54mm2. The input matching (S11) is below −10 dB from 1 GHz to 1.7 GHz. At a local-oscilator (LO) frequency of 1.3 GHz, intermediate-frequency (IF) of 10 MHz and default current settings, the CRR achieves a conversion gain of 41.5 dB, a double-sideband (DSB) NF of 6.5 dB, and an IIP3 of −28.2 dBm while consuming 1.66 mA from a 1.2 V supply.
Towards a 1.1 mm2 free-floating wireless implantable neural recording SoC (2018)

A 1.1 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> sized free-floating wireless implantable neural recording (FF-WINeR) system-on-a-chip (SOC) is designed and tested in vitro toward developing stand-alone neural probes in the form of small untethered pushpins (1 mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> ) to be distributed across the areas of interest in the brain. Pre-recorded single unit activity (SUA) from neurons injected in saline solution are recorded through the probe single tungsten electrode, amplified by a low noise amplifier (LNA) with 53 dB gain, and filtered within 0.1-12 kHz band. The amplified SUA signals are digitized by a 10 bits voltage controlled oscillator (VCO) based analog-to-digital converter (ADC), and transmitted to an external data receiver (Rx) through an inductive link shared for power transmission using an impulse radio (IR)-based near-field uplink data telemetry at 800 kbps data rate and <;0.3 mW power budget.
Decomposition of Dimethyl Sulfoxide Aided by Ethylene Glycol, Acetamide, and Related Compounds1 (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDecomposition of Dimethyl Sulfoxide Aided by Ethylene Glycol, Acetamide, and Related Compounds1Vincent J. Traynelis and William L. HergenrotherCite this: J. Org. Chem. 1964, 29, 1, 221–222Publication Date (Print):January 1, 1964Publication History Published online1 May 2002Published inissue 1 January 1964https://pubs.acs.org/doi/10.1021/jo01024a505https://doi.org/10.1021/jo01024a505research-articleACS PublicationsRequest reuse permissionsArticle Views1228Altmetric-Citations100LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts