gebhart/patrepeval huggingface dataset:
Multi-User Data Detection in Massive MIMO with 1-Bit ADCS (2023)

We provide new analytical results on the uplink data detection in massive multiple-input multiple-output systems with 1-bit analog-to-digital converters. The statistical properties of the soft-estimated symbols (i.e., after linear combining and prior to the data detection process) have been previously characterized only for a single user equipment (UE) and uncorrelated Rayleigh fading. In this paper, we consider a multi-UE setting with correlated Rayleigh fading, where the soft-estimated symbols are obtained by means of maximum ratio combining based on imperfectly estimated channels. We derive a closed-form expression of the expected value of the soft-estimated symbols, which allows to understand the impact of the specific data symbols transmitted by the interfering UEs. Building on this result, we design efficient data detection strategies based on the minimum distance criterion, which are compared in terms of symbol error rate and complexity.
A multichannel affine projection algorithm with applications to multichannel acoustic echo cancellation (1996)

A straightforward generalization of the so-called affine projection algorithm (APA) to the multichannel (MC) case is easily obtained. However, due to the strong correlation between the input signals of the various channels, the resulting algorithm converges very slowly. The article describes the way to overcome this problem and derives an efficient algorithm that makes use of additional orthogonal projections.
Design andCharacterization ofanElectric Field BasedMediumVoltage Transducer (2008)

Theincreasing interest inperforming powerquality measurement campaign ondistribution systems isactually in contrast withthefewavailability ofsuitable voltage transducers at affordable costs. Inthis paper, a transducer forpowerquality assessment in mediumvoltage networks isdesigned and characterized. Thedevice isbasedonthemeasurement ofthe electric fieldThepresented results showitsgoodaccuracy performance andseemtoconfirm that itcanbeusefully employed in powersystems.
A Novel Tunable Aromatic Bromination Method Using Alkyl Bromides and Sodium Hybride in DMSO. (2006)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Flash glucose monitoring improves glycemia in higher risk patients: a longitudinal, observational study under real-life settings (2019)

Under real-world conditions, flash monitoring is associated with rapid and sustained reduction in dysglycemia with high-frequency scanners demonstrating more significant reduction in hyperglycemia.
On the use of the Norwegian Geotechnical Institute's prototype seabed-coupled shear wave vibrator for shallow soil characterization - II. Joint inversion of multimodal Love and Scholte surface waves (2011)

Seismic data generated by a novel, seabed-coupled, shear-wave vibrator (prototype) and recorded by a densely-populated, multicomponent ocean-bottom cable allowed several modes of propagation of Love and Scholte waves to be retrieved in a relatively wide frequency band. Both global dispersion curves and local dispersion curves are extracted in the frequency–wavenumber (f–k) domain and inverted with a multimodal joint Scholte and Love wave inversion algorithm. Monte Carlo inversion is used for a estimating the global S-wave velocity profile of the seabed sediments whereas laterally constrained inversion is used to detect lateral variations of the layer interface depths. The results are in agreement and allowed consistent full-waveform simulation to be performed. The investigation depth is limited to around 40 m due to the low shear wave velocities within the shallow clay layer.
Defect Tolerance and the Effect of Structural Inhomogeneity in Plasmonic DNA-Nanoparticle Superlattices* (2020)

Bottom-up assemblies of plasmonic nanoparticles exhibit unique optical effects such as tunable ref71_lection, optical cavity modes, and tunable photonic resonances. Here, we compare detailed simulations with experiment to explore the effect of structural inhomogeneity on the optical response in DNA-gold nanoparticle superlattices. 1304In particular, we explore the effect of background environment, nanoparticle polydispersity (&gt;10%), and variation in nanoparticle placement (~5%). At volume fractions less than 20% Au, the optical response is insensitive to particle size, defects, and inhomogeneity in the superlattice. At elevated volume fractions (20% and 25%), structures incorporating different sized nanoparticles (10, 20, and 40 nm diameter) each exhibit distinct far-field extinction and near-field properties. These optical properties are most pronounced in lattices with larger particles, which at fixed volume fraction have greater plasmonic coupling than those with smaller particles. Moreover, the incorporation of experimentally informed inhomogeneity leads to variation in far-field extinction and inconsistent electric-field intensities throughout the lattice, demonstrating that volume fraction is not sufficient to describe the optical properties of such structures. These data have important implications for understanding the role of particle and lattice inhomogeneity in determining the properties of plasmonic nanoparticle lattices with deliberately designed optical properties.
Unintentional magnet reversion of an implanted cardiac defibrillator by an electronic cigarette (2020)

Electronic cigarettes, or e-cigarettes, are nicotine delivery systems initially thought be a safer alternative to cigarette smoking as well as useful adjuncts for smoking cessation.1 More recently, attention has been directed by the Centers for Disease Control and Prevention at serious pulmonary complications from e-cigarette use, raising important public health concerns.2 This has been echoed in the scientific literature by demands for stricter regulations for commercialization of these products.
AWireless Micromachined Radiation Sensor (2007)

Networked radiation sensors are envisioned for monitoring public spaces with high-pedestrian traffic such as train stations, football stadiums, and shopping malls. Wireless communication between sensors can enable rapid and low-cost deployment and reconfiguration of such networks. By employing a dischargebased transmission method, this project aims to enhance a micromachined Geiger counter with wireless communication capability.The device consists of a planar, 3-electrode, metal-on-glass design utilizing a high-impedance middle-electrode sandwiched between two permanent magnets. This 3-electrode approach enables greater control of discharge energy, resulting in faster response time, wider dynamic range, lower power consumption, and superior durability.The 3-electrode design widens the available operating range and achieves 10x‐100ximprovement in detector sensitiv i t y. Wireless measurements showed an inherent sensor transmission bandwidth exceeding 3GHz, while detecting ultra-low - l evel (0.1µCi‐1.0µCi) b-sources. Improved transmitter performance is achieved with the employment of miniaturized permanent magnets, which increases ionization efficiency and increases the transmission bandwidth by more than 2x.This project is supported by the Engineering Research Centers Program of the National Science Foundation under award number EEC-9986866.
Repetition-rate multiplication of high-repetition-rate pulse trains using all-pass filters and its realization condition (2002)

The repetition-rate multiplication of a pulse train outside the laser cavity by using all-pass filters is discussed. Schemes based on the phase responses of optical all-pass filters for multiplying the repetition-rate of an optical pulse train are presented and the design of the required all-pass filters is also presented. These methods, in principle, can produce a uniform pulse train with a multiplied pulse repetition-rate without energy loss. The error analyses of these methods are discussed and the error ranges ofthe parameters are given.
Insulin-stimulated Protein Tyrosine Phosphorylation in Intact Cells Evaluated by Giant Two-dimensional Gel Electrophoresis (1989)

We have studied the insulin-stimulated phosphorylation of proteins in NIH 3T3 cells expressing high numbers of human insulin receptors (HIR 3.5 cells) using the technique of giant two-dimensional gel electrophoresis. In serum-deprived cells, insulin stimulated the phosphorylation of more than 25 proteins; all but two of these were also phosphorylated in response to 15% (v/v) fetal bovine serum, which also stimulated the phosphorylation of additional proteins thought to be direct substrates for protein kinase C. In cells pretreated insulin specifically stimulated the phosphorylation insulin specifically stimulated the phosphorylation of at least 26 predominantly cytosolic proteins, only one of which was observed in insulin-treated cells not exposed to phenylarsine oxide. Serum was without effect in cells pretreated with phenylarsine oxide. In phenylarsine oxide-pretreated cells, phosphoamino acid analysis of 10 of the most highly labeled insulin-stimulated phosphoproteins showed that all 10 were labeled predominantly or exclusively on tyrosine residues. The phosphorylation of several of these could be stimulated in vitro by the addition of insulin to a detergent extract of cells in the presence of Mn2+ and ATP. In general, the insulin-stimulated phosphorylations observed in the presence of phenylarsine oxide were more rapid than those observed in its absence. Finally, a variety of other growth factors and mitogens did not stimulate any of the insulin-stimulated phosphorylations in the presence of phenylarsine oxide. Thus, the use of this inhibitor apparently unmasked a number of novel insulin-specific protein phosphorylations that were ordinarily undetectable. We suggest that at least some of these proteins may be direct substrates for the insulin receptor protein tyrosine kinase and may play significant roles in insulin action.
Three-Year Follow-up of the Prospective, Randomized, Controlled Trial of Coflex Interlaminar Stabilization vs Instrumented Fusion in Patients With Lumbar Stenosis (2016)

CCS, composite clinical successCEC, clinical events committeeFDA, Food and Drug AdministrationIDE, investigational device exemptionILS, Coflex Interlaminar StabilizationODI, Oswestry Disability IndexSF-12, Short-Form 12VAS, visual analogue scalesZCQ, Zurich Claudication Questionnaire.
ChemInform Abstract: FACILE RETRO DIECKMANN REACTIONS OF 3‐OXOCARBAPENAM ESTERS (1985)

Abstract Die bicyclischen β‐Lactam‐ketone (I) reagieren mit verschiedenen Nucleophilen (II)‐(V) unter Ringöffnung zu den Azetidinonen (VI).
Proximity-dependent labeling identifies dendritic cells that drive the tumor-specific CD4 + T cell response (2022)

Abstract Dendritic cells (DCs) are uniquely capable of transporting tumoral antigens to tumor-draining lymph nodes (tdLNs), and also interact with effector T cells within the tumor microenvironment (TME) itself, mediating both natural antitumor immunity and the response to checkpoint blockade immunotherapy. Using LIPSTIC (Labeling Immune Partnerships by SorTagging Intercellular Contacts)-based single-cell transcriptomics, we identify individual DCs capable of presenting antigen to CD4 + T cells in the tdLN as well as inside the tumor microenvironment (TME). Our findings reveal that DCs with similar hyperactivated transcriptional phenotypes interact with helper T cells both within tumors and in the tdLN, and that checkpoint blockade drugs enhance these interactions. These findings show that a relatively small fraction of DCs is responsible for most of the antigen presentation within the tdLN and TME to both CD4 + and CD8 + tumor-specific T cells and that classical checkpoint blockade enhances CD40-driven DC activation at both sites.
[Clinical work during medical education in Linköping. This item in education is a substitute to temporary employment]. (1995)

Kliniskt arbete i Linkopings lakarutbildning. Moment i utbildningen ersatter vikariaten [Clinical work during medical education in Linkoping. This item in education is a substitute to temporary employment].
Intermediate uveitis and polyneuropathy in an elderly patient due to sarcoidosis (1999)

Sarcoidosis was observed in a 60-year-old female with symptoms of intermediate uveitis and polyneuropathy. Although these symptoms are rarely seen for the first time in patients over 50 years of age, this combination should alert the physician to the possible diagnosis of sarcoidosis.
Design and Deployment of an IoT Network Based on LoRa (2017)

International audience
Dimension Reduction with Gene Expression Data Using Targeted Variable Importance Measurement (2014)

Background: When a large number of candidate variables are present, a dimension reduction procedure is usually conducted to reduce the variable space before the subsequent analysis is carried out.The goal of dimension reduction is to find a list of candidate genes with a more operable length ideally including all the relevant genes.Leaving many uninformative genes in the analysis can lead to biased estimates and reduced power.Therefore, dimension reduction is often considered a necessary predecessor of the analysis because it can not only reduce the cost of handling numerous variables, but also has the potential to improve the performance of the downstream analysis algorithms.Results: We propose a TMLE-VIM dimension reduction procedure based on the variable importance measurement (VIM) in the frame work of targeted maximum likelihood estimation (TMLE).TMLE is an extension of maximum likelihood estimation targeting the parameter of interest.TMLE-VIM is a two-stage procedure.The first stage resorts to a machine learning algorithm, and the second step improves the first stage estimation with respect to the parameter of interest.Conclusions: We demonstrate with simulations and data analyses that our approach not only enjoys the prediction power of machine learning algorithms, but also accounts for the correlation structures among variables and therefore produces better variable rankings.When utilized in dimension reduction, TMLE-VIM can help to obtain the shortest possible list with the most truly associated variables.
Forward Modeling of Log Response in Geopressured Formations Reveals Valuable Insights to the Various Pore-Pressure Prediction Techniques (2001)

Recognizing that pore pressure and pressure regimes are critical in the evolution of hydrocarbon provinces, geologists and drilling engineers joined forces to bring you new technology in this publication. The original publication was an outgrowth of an international forum sponsored by the Houston chapter of the American Association of Drilling Engineers. Experts in pore-pressure prediction from the geologic, geophysical, reservoir, and drilling communities were brought together to share the state of the art from each discipline. This product will interest pore-pressure interpreters, basin modelers, explorationists, drilling engineers, and rock physicists.
On the impedance response of reactions influenced by mass transfer (2017)

A direct relationship is derived between the charge-transfer resistance and the resistive terms ascribable to diffusion for a faradaic reaction influenced by transport of the reacting species to the electrode. The charge-transfer resistance is shown to approach a finite value for potentials at which the current is limited by mass transfer and, conversely, the diffusion impedance approaches a finite value when the current is controlled by kinetics. Supporting experimental results are presented for both an irreversible (oxygen reduction reaction) and a quasi-reversible (ferrocyanide oxidation) electrochemical systems investigated with a rotating- disk electrode.
RING-H2 Protein WSSV249 from White Spot Syndrome Virus Sequesters a Shrimp Ubiquitin-Conjugating Enzyme, PvUbc, for Viral Pathogenesis (2005)

ABSTRACT Modification of proteins by ubiquitin is essential for numerous cellular processes. The RING-H2 finger motif has been implicated in ubiquitin-conjugating enzyme (E2)-dependent ubiquitination. Four proteins, WSSV199, WSSV222, WSSV249, and WSSV403, from white spot syndrome virus (WSSV) contain the RING-H2 motif. Here we report that WSSV249 physically interacts with a shrimp ubiquitin-conjugating enzyme, PvUbc, and mediates ubiquitination through its RING-H2 motif in the presence of E1 and PvUbc. Mutations of the putative zinc coordination residues in the RING-H2 domain of WSSV249, however, ablate ubiquitination efficiency. In addition, the RING-H2 domain of WSSV249 is capable of ubiquitination with UbcH1, UbcH2, UbcH5a, UbcH5b, UbcH5c, UbcH6, and UbcH10, respectively, exhibiting a low degree of E2 specificity. Significantly, the expression of WSSV249 and PvUbc increased during infection, as revealed by real-time PCR. Furthermore, in situ hybridization showed that WSSV249 and PvUbc display similar expression patterns in infected shrimps, and immunofluorescence and immunohistochemistry assays showed an increase of PvUbc in infected shrimp cells. These results suggest that the RING-H2 protein WSSV249 from WSSV may function as an E3 ligase via sequestration of PvUbc for viral pathogenesis in shrimp.
Fast Visualization by Shear-Warp on Quadratic Super-Spline Models Using Wavelet Data Decompositions (2006)

We develop the first approach Tor interactive volume visualization based on a sophisticated rendering method of shear-warp type, wavelet data encoding techniques, and a trivariate spline model, which has been introduced recently. As a first step of our algorithm, we apply standard wavelet expansions to represent and decimate the given gridded three-dimensional data. Based on this data encoding, we give a sophisticated version of the shear-warp based volume rendering method. Our new algorithm visits each voxel only once taking advantage of the particular data organization of octrees. In addition, the hierarchies of the data guide the local (re)construction of the quadratic super-spline models, which we apply as a pure visualization tool. The low total degree of the polynomial pieces allows to numerically approximate the volume rendering integral efficiently. Since the coefficients of the splines are almost immediately available from the given data, Bernstein-Bezier techniques can be fully employed in our algorithms. In this way, we demonstrate that these models can be successfully applied to full volume rendering of hierarchically organized data. Our computational results show that (even when hierarchical approximations are used) the new approach leads to almost artifact-free visualizations of high quality for complicated and noise-contaminated volume data sets, while the computational effort is considerable low, i.e. our current implementation yields 1-2 frames per second for parallel perspective rendering a 2563 volume data set (using simple opacity transfer functions) in a 5122 view-port.
Molecularly Imprinted Mesoporous Organosilica (2011)

We have prepared molecularly imprinted mesoporous organosilica (MIMO) using a semicovalent imprinting technique. A thermally reversible covalent bond was used to link a bisphenol A (BPA) imprint molecule to a functional alkoxysilane monomer at two points to generate a covalently bound imprint precursor. This precursor was incorporated into a cross-linked periodic mesoporous silica matrix via a typical acid-catalyzed, triblock copolymer-templated, sol-gel synthesis. Evidence of imprint sites buried in the pore walls was found through careful characterization of the imprinted material and its comparison to similarly prepared non-imprinted mesoporous organosilica (NIMO) and pure periodic mesoporous silica (PMS). After thermal treatment, the imprinted material (MIMO-ir) removed more than 90% of appropriately sized bisphenol species from water, yet showed significantly lower binding for both smaller and larger molecules containing phenol moieties. Identically treated NIMO-ir showed much poorer retention behavior than MIMO-ir for the same bisphenol species and behaved only slightly better than PMS-ir.
Pharmacology of bisphosphonates (2019)

The biological effects of the bisphosphonates (BPs) as inhibitors of calcification and bone resorption were first described in the late 1960s. In the 50 years that have elapsed since then, the BPs have become the leading drugs for the treatment of skeletal disorders characterized by increased bone resorption, including Paget's disease of bone, bone metastases, multiple myeloma, osteoporosis and several childhood inherited disorders. The discovery and development of the BPs as a major class of drugs for the treatment of bone diseases is a paradigm for the successful journey from "bench to bedside and back again". Several of the leading BPs achieved "blockbuster" status as branded drugs. However, these BPs have now come to the end of their patent life, making them highly affordable. The opportunity for new clinical applications for BPs also exists in other areas of medicine such as ageing, cardiovascular disease and radiation protection. Their use as inexpensive generic medicines is therefore likely to continue for many years to come. Fifty years of research into the pharmacology of bisphosphonates have led to a fairly good understanding about how these drugs work and how they can be used safely in patients with metabolic bone diseases. However, while we seemingly know much about these drugs, a number of key aspects related to BP distribution and action remain incompletely understood. This review summarizes the existing knowledge of the (pre)clinical and translational pharmacology of BPs, and highlights areas in which understanding is lacking.
Alum sludge land application and its effect on plant growth (1994)

Addition of phosphorus fertilizer corrected the phosphorus deficiency found in fescue grass at higher sludge application rates. These investigators conducted three greenhouse experiments to determine the impact of alum sludge from the Harwood's Mill water treatment plant, Newport News, Va., on the growth and chemical composition of fescue grass. Fescue yields decreased with increased sludge addition, a trend that was attributed to reductions in plant‐available phosphorus (P) at higher loadings. Supplemental P fertilization corrected this deficiency. Lime addition did not affect yield. The presence of manganese and copper in the sludge increased metal uptake by the plants but did not affect yield.
Supplementary Fig 1B from Single Nucleotide Polymorphism–Based Genome-Wide Chromosome Copy Change, Loss of Heterozygosity, and Aneuploidy in Barrett's Esophagus Neoplastic Progression (2023)

Supplementary Fig 1B from Single Nucleotide Polymorphism–Based Genome-Wide Chromosome Copy Change, Loss of Heterozygosity, and Aneuploidy in Barrett's Esophagus Neoplastic Progression
XRMF applications of a monolithic, polycapillary, focusing x-ray optic (1996)

A monolithic, polycapillary, x-ray optic was adapted to a laboratory-based x-ray microprobe to evaluate the potential of the optic for x-ray micro fluorescence analysis. The polycapillary was capable of collecting x-rays over a 6 degree angle from a point source and focusing them to a spot approximately 40 µm diameter. The high intensities expected from this capillary should be useful for determining and mapping minor to trace elements in materials. Fig. 1 shows a sketch of the capillary with important dimensions. The microprobe had previously been used with straight and with tapered monocapillaries. Alignment of the monocapillaries with the focal spot was accomplished by electromagnetically scanning the focal spot over the beveled anode. With the polycapillary it was also necessary to manually adjust the distance between the focal spot and the polycapillary. The focal distance and focal spot diameter of the polycapillary were determined from a series of edge scans.