gebhart/patrepeval huggingface dataset:
A Generative Model of People in Clothing (2017)

We present the first image-based generative model of people in clothing for the full body. We sidestep the commonly used complex graphics rendering pipeline and the need for high-quality 3D scans of dressed people. Instead, we learn generative models from a large image database. The main challenge is to cope with the high variance in human pose, shape and appearance. For this reason, pure image-based approaches have not been considered so far. We show that this challenge can be overcome by splitting the generating process in two parts. First, we learn to generate a semantic segmentation of the body and clothing. Second, we learn a conditional model on the resulting segments that creates realistic images. The full model is differentiable and can be conditioned on pose, shape or color. The result are samples of people in different clothing items and styles. The proposed model can generate entirely new people with realistic clothing. In several experiments we present encouraging results that suggest an entirely data-driven approach to people generation is possible.
Distinct Location and Prevalence of α-, β-Catenins and γ-Catenin/Plakoglobin in Developing and Denervated Skeletal Muscle (1998)

We studied the distribution of alpha-catenin, beta-catenin and gamma-catenin/plakoglobin in developing, adult and denervated mouse skeletal muscle. During primary myogenesis, all three catenins present a subsarcolemmal distribution within primary myotubes. During secondary myogenesis they accumulate at myotube-myotube contacts. In contrast to the other catenins, gamma-catenin is strongly expressed in the sarcoplasm. In adult muscle, all three catenins are localized on the presynaptic elements of the neuromuscular junction. In denervated muscles, alpha- and beta-catenins are upregulated like N- and M-cadherin, while the levels of gamma-catenin/plakoglobin remain unchanged. The developmental changes in localization and regulation of alpha- and beta-catenins in muscle compared to gamma-catenin/plakoglobin are suggestive of a privileged association of alpha- and beta-catenins with N- and M-cadherins, while gamma-catenin/plakoglobin appears to be expressed quite independently and must assume a different role during myogenesis.
PV inverter test setup for European efficiency, static and dynamic MPPT efficiency evaluation (2008)

This paper concerns the evaluation of performance of grid-connected PV inverters in terms of conversion efficiency, European efficiency, static and dynamic MPP efficiency. Semi-automated tests were performed in the PV laboratory of the Institute of Energy Technology at the Aalborg University (Denmark) on a commercial transformerless PV inverter. Thanks to the available experimental test setups, that provide the required high measuring accuracy, and the developed PV simulator, which is required for MPPT performance evaluation, PV Inverters can be pretested before being tested by accredited laboratories.
Reverse Traffic Channel MAC Design of cdma2000 1xEV-DO Revision A System (2005)

cdma2000 1xEV-DO (DO), also known as IS-856, is a third generation (3G) wireless solution providing high-speed mobile Internet access. cdma2000 1xEV-DO revision A (DO-RevA) system provides further enhancements to DO, such as higher system capacity and advanced quality-of-service (QoS) support In this paper we motivate and describe the design of the reverse link traffic channel MAC (RTCMAC) of DO-RevA system, which uses a novel combination of centralized specification of flow behavior together with autonomous mobile packet allocation subject only to resource congestion control. We demonstrate that RTCMAC achieves full resource allocation flexibility through an efficient robust design, well suited to the CDMA reverse link.
ChemInform Abstract: Free Radicals in Oxidation Processes (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Diagnosing HIT: the need for speed (2020)

In this issue of Blood, Marchetti et al describe a novel diagnostic algorithm for heparin-induced thrombocytopenia (HIT) based on the 4Ts score and 2 rapid immunoassays (IAs) that correctly classified >95% of patients within a 60-minute analytical window.(1)
Using DDM Asymmetry Metrics for Wind Direction Retrieval From GPS Ocean-Scattered Signals in Airborne Experiments (2013)

Reflectometry of signals of opportunity such as those emitted by a global navigation satellite system, known as GNSS-R, has been developed over the past years as a technique with great potential for ocean scatterometry, among other applications. Different approaches have been proposed to use GNSS-R for remote sensing of ocean surface roughness. One of them is based on deriving some descriptor/metric from the measured delay-Doppler map (DDM) and directly relating it to a geophysical property of the scattering surface. For instance, different descriptors have been proposed in the literature to measure the DDM spreading caused by the increase in ocean surface mean square slopes due to surface winds. In this paper, a new descriptor based on the DDM is proposed for wind direction retrieval. This descriptor, designated as the skewness angle φ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1,skew</sub> , measures the asymmetry in the DDM power distribution along the Doppler frequency axis, and it was modeled as a function of wind direction by means of a simulation study. Then, that model was validated using real GNSS-R data from an airborne experiment. After validation, the DDM skewness model was successfully used for wind direction retrieval, with a resulting rms error on the order of 20 °.
Carbonate addition - an effective remedy against poor activated sludge settling properties and alkalinity conditions in small wastewater treatment plants (2004)

The impact of marble powder on the performance of small seasonal treatment plants dealing with high ammonia concentrated wastewater has been investigated. The carbonate has been added to one of two parallel lab-scale SBR-systems as an alkalinity depot and a bio-carrier. The focus of the monitoring program was put on the measurement of carbon fractions in the liquid and the solid phase and on the alkalinity conditions. Monitoring results show a significant correlation between carbonate dosage (and corresponding inorganic carbon concentration and pH-value) and sludge volume index and nitrification rate.
SoH-Aware Reconfiguration in Battery Packs (2016)

Cell imbalance, a notorious but widely found issue, degrades the performance and reliability of large battery packs, especially for cells connected in series where their overall capacity delivery is dominated by the weakest cell. In this paper, we exploit the emerging reconfigurable battery packs to mitigate the cell imbalance via the joint consideration of system reconfigurability and State-of-Health (SoH) of cells. Via empirical measurements and validation, we observe that more capacity can be delivered when cells with similar SoH are connected in series during discharging. Based on this observation, we propose two SoH-aware reconfiguration algorithms focusing on fully and partially reconfigurable battery packs, and prove their (near) optimality in capacity delivery. We evaluate the proposed reconfiguration algorithms analytically, experimentally, and via emulations, showing 10%–60% improvement in capacity delivery when compared with SoH-oblivious approaches, especially when facing severe cell imbalance.
Biochemical Modulation of Fluoropyrimidines by Antifolates and Folates in anIn VitroModel of Human Leukemia (1990)

Although 5-fluorouracil (FUra) is one of the most effective cytotoxic agents in the treatment of various solid tumors (carcinomas of the gastro-intestinal tract, breast, head and neck), remissions occur in only 20 to 30% of cases and usually are of short duration. Recently, preclinical studies have shown that the antitumor activity of FUra can be potentiated by modulating the metabolism of this drug by using other substances, in particular antifolates of folates. Pretreatment with antifolates may, by blocking de novo purine biosynthesis and consequently increasing phosphoribosyl pyrophosphate (PRPP) pools, enhance the conversion of FUra to active fluoronucleotide pools via orotate phosphoribosyltransferase. Methotrexate (MTX) pretreatment may also enhance binding of the fluoropyrimidine inhibitor, 5-fluodeoxyuridylate (FdUMP), to the target enzyme, thymidylate synthase (TS), indirectly by increasing dihydrofolate polyglutamates or directly, as MTX polyglutamates, by enhancing the formation of ternary complexes with FdUMP and TS. Exogenous folates, in particular 5-formyltetrahydrofolate (folinate, leucovorin, LV), can, by raising the intracellular levels of 5, 10-methylenetetrahydrofolate, lead to increased formation and stabilization of the ternary complex formed by TS, the folate coenzyme, and FdUMP. In vitro studies have also shown potentiation of FUra cytotoxicity by antifolates and folates against human lymphoblastic leukemia cell lines. Thus, while FUra may have little or no single agent activity in leukemias and lymphomas, it may be converted to an active drug in these neoplasms by appropriate modulation. Clinical studies of sequential MTX-FUra or combined LV-FUra based upon experimental tumor results reviewed herein, are warranted.
Dynamic Monitoring Systems for Structures under Extreme Loads (2011)

The dynamic monitoring of civil structures such as buildings and bridges is traditionally approached using acceleration and velocity sensors. When a monitoring program is designed to address concerns related to the level of strain in certain members, fatigue or displacements due to extreme loads, it is sometimes advantageous to measure those parameters directly, instead of deriving them from acceleration or velocity data. Inhomogeneous construction materials such as concrete, stone or masonry require the use of long-gauge sensors to measure strain, since local sensors can provide erroneous data due to local material changes. On the other hand, acceleration and tilt sensors are very useful to capture the global deformations and displacements. The development of long-gauge-length fiber optic sensors can be considered as a useful addition to the toolkit of those interested in the structural dynamics. The system can monitor structures over long periods of time at acquisition frequencies up to 10 kHz and with sub-microstrain resolution. The possibility of obtaining static and dynamic measurements from the same sensor is another advantage of this technology. For acceleration and tilt monitoring, MEMS sensors are now recognized as a powerful and low-cost alternative to more traditional sensor types. Fully-integrated sensors with 3-axis accelerometers and two-axis tiltmeters are now available in a compact packaging that also contain all data acquisition electronics and can be easily deployed in new or existing structures, connecting them directly to an Ethernet network. This contribution briefly introduces fiber optic and MEMS sensing technologies and will than illustrate their application to structural health monitoring through several examples, including the new I35W bridge in Minneapolis USA, the Ile d’Orléans suspension Bridge in Québec Canada and the shaking-table test of a full-scale masonry building reinforced with composite materials.
Cover Picture: Mesostructured Prussian Blue Analogues (Angew. Chem. Int. Ed. 3/2008) (2007)

Mesostructured Prussian blue analogues have been prepared by ligand-assisted templating in formamide. These materials, reported by M. MacLachlan et al. on page 511 ff., contain cyanide-linked metal centers organized around an alkyl pyrazinium template with lamellar, hexagonal, or cubic periodicity. The cover picture shows a synthesis of these compounds against a background painting dating from the early 1800s showing two chemists making Prussian blue, the oldest-known coordination complex. (Graphic by Elizabeth Varty; background image courtesy of Wisconsin Academy of Sciences, Arts and Letters.)
What Papers Are People Citing and What Are People Reading? (2018)

ADVERTISEMENT RETURN TO ISSUEEditorialNEXTWhat Papers Are People Citing and What Are People Reading?Craig W. LindsleyCraig W. LindsleyMore by Craig W. Lindsleyhttp://orcid.org/0000-0003-0168-1445Cite this: ACS Chem. Neurosci. 2018, 9, 9, 2097–2098Publication Date (Web):September 19, 2018Publication History Published online19 September 2018Published inissue 19 September 2018https://pubs.acs.org/doi/10.1021/acschemneuro.8b00438https://doi.org/10.1021/acschemneuro.8b00438editorialACS PublicationsCopyright © 2018 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views826Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (2 MB) Get e-AlertscloseSUBJECTS:Chemical neuroscience,Nervous system diseases,Pharmaceuticals Get e-Alerts
Increasing depth resolution of electron microscopy of neural circuits using sparse tomographic reconstruction (2010)

Future progress in neuroscience hinges on reconstruction of neuronal circuits to the level of individual synapses. Because of the specifics of neuronal architecture, imaging must be done with very high resolution and throughput. While Electron Microscopy (EM) achieves the required resolution in the transverse directions, its depth resolution is a severe limitation. Computed tomography (CT) may be used in conjunction with electron microscopy to improve the depth resolution, but this severely limits the throughput since several tens or hundreds of EM images need to be acquired. Here, we exploit recent advances in signal processing to obtain high depth resolution EM images computationally. First, we show that the brain tissue can be represented as sparse linear combination of local basis functions that are thin membrane-like structures oriented in various directions. We then develop reconstruction techniques inspired by compressive sensing that can reconstruct the brain tissue from very few (typically 5) tomographic views of each section. This enables tracing of neuronal connections across layers and, hence, high throughput reconstruction of neural circuits to the level of individual synapses.
Enhanced Selective Oxidation of Benzyl Alcohol via In Situ H2O2 Production over Supported Pd-Based Catalysts (2021)

Bimetallic Pd-Fe catalysts supported on TiO2 are shown to be highly effective toward the selective oxidation of benzyl alcohol to benzaldehyde via the in situ production of H2O2 from molecular H2 and O2, under conditions where no reaction is observed with molecular O2 alone. The rate of benzyl alcohol oxidation observed over supported Pd-Fe nanoparticles is significantly higher than those of either Pd-Au or Pd-only analogues. This enhanced activity can be attributed to the bifunctionality of the Pd-Fe catalyst to both synthesize H2O2 and catalyze the production of oxygen-based radical specie,s as indicated by an electron paramagnetic resonance analysis. Further studies also reveal the noninnocent nature of the solvent, resulting in the propagation of radical generation pathways.
Data from Episomal Expression of Truncated Listeriolysin O in LmddA-LLO–E7 Vaccine Enhances Antitumor Efficacy by Preferentially Inducing Expansions of CD4<sup>+</sup>FoxP3<sup>−</sup> and CD8<sup>+</sup> T Cells (2023)

&lt;div&gt;Abstract&lt;p&gt;Studies have shown that &lt;i&gt;Listeria monocytogenes&lt;/i&gt; (Lm)–based vaccine expressing a fusion protein comprising truncated listeriolysin O (LLO) and human papilloma virus (HPV) E7 protein (Lm-LLO–E7) induces a decrease in regulatory T cells (Treg) and complete regression of established, transplanted HPV-TC-1 tumors in mice. However, how the Lm-based vaccine causes a decrease in Tregs remains unclear. Using a highly attenuated Lm &lt;i&gt;dal dat&lt;/i&gt; Δ&lt;i&gt;actA&lt;/i&gt; strain (LmddA)–based vaccine, we report here that the vector LmddA was sufficient to induce a decrease in the proportion of Tregs by preferentially expanding CD4&lt;sup&gt;+&lt;/sup&gt;FoxP3&lt;sup&gt;−&lt;/sup&gt; T cells and CD8&lt;sup&gt;+&lt;/sup&gt; T cells by a mechanism dependent on and directly mediated by LLO. Episomal expression of a nonhemolytic truncated LLO in Lm (LmddA-LLO) significantly augmented the expansion, thus further decreasing Treg frequency. Although adoptive transfer of Tregs compromised the antitumor efficacy of the LmddA-LLO–E7 vaccine, a combination of LmddA-LLO and an Lm-based vaccine expressing E7 protein (Lm–E7) induced complete regression against established TC-1 tumors. An engineered LLO-minus Lm expressing perfringolysin O (PFO) that enables the recombinant bacteria to exit from the phagolysosome without LLO confirmed that the adjuvant effect was dependent on LLO. These results suggest that LLO may serve as a promising adjuvant by preferentially inducing the expansions of CD4&lt;sup&gt;+&lt;/sup&gt;FoxP3&lt;sup&gt;−&lt;/sup&gt; T cells and CD8&lt;sup&gt;+&lt;/sup&gt; T cells, thus reducing the ratio of Tregs to CD4&lt;sup&gt;+&lt;/sup&gt;FoxP3&lt;sup&gt;−&lt;/sup&gt; T cells and to CD8&lt;sup&gt;+&lt;/sup&gt; T cells favoring immune responses to eradicate tumor. &lt;i&gt;Cancer Immunol Res; 2(9); 911–22. ©2014 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Abstract P62: Older Adults With Cerebral Small Vessel Disease Show Increased Levels of Circulating Vascular Endothelial Growth Factor D (2021)

Introduction: Cerebral small vessel disease (SVD) resulting from pathological changes in cerebral microvessels is a common precursor of stroke and dementia. Progressive and insidious damage to the cerebral microvasculature may trigger angiogenic processes to promote vessel repair. However, few previous studies have explored the angiogenic response to SVD. In a cohort of older adults with early evidence of SVD, we aimed to examine circulating levels of vascular endothelial growth factor D (VEGF-D)—a secreted glycoprotein with high angiogenic and lymphangiogenic potential—which has previously been linked to heart failure, atrial fibrillation, and ischemic stroke. Methods: Sixty independently living older adults (mean age = 69.7 years; SD = 7.5; age range 55-90 years; 38.3% male) free of dementia or clinical stroke were recruited from the community and underwent venipuncture and brain MRI. Plasma was assayed for proangiogenic factors (VEGF-A, VEGF-C, VEGF-D, Tie-2, Flt-1). MRI changes thought to represent microvascular pathologies (white matter hyperintensities, microbleeds and lacunes) were evaluated and total SVD load was determined using a previously validated score. Multiple linear regression examined the relationship between circulating proangiogenic proteins levels and total SVD load. Results: Moderate/severe white matter hyperintensity burden was identified by Fazekas scale in 40.0% of participants, small lacunes were identified in 13.3% and microbleeds in 6.7%. Simple linear regression revealed a positive relationship between circulating VEGF-D and total SVD score (p = .019), which remained significant in multiple regression controlling for age, sex and Framingham stroke score (p = .017). VEGF-D was significantly positively correlated with VEGF-C (r = .37), Flt-1 (r = .31) and Tie-2 (r = .42). Conclusions: These findings suggest that elevated levels of circulating VEGF-D correspond with greater damage to the cerebral microvasculature in older adults with no history of clinical stroke or dementia. Additional studies are warranted to determine whether activation of systemic proangiogenic growth factors represents an early attempt to rescue the vascular endothelium and repair damage in cerebral SVD.
Biochemistry of Oleoresinosis (1987)

Elevated levels of monoterpenes and diterpene resin acids are produced in the stems of lodgepole pine (Pinus contorta var latifolia) saplings when wounded and inoculated with the blue-stain fungus Ceratocystis clavigera or when wounded and treated with a pectic fragment from tomato leaves (PIIF) or a fungal cell wall fragment (chitosan). This induced defensive response (hyperoleoresinosis) is the result of a transient rise in the ability to biosynthesize cyclic monoterpenes and diterpene resin acids as measured by the in vivo incorporation of label from [U-(14)C]sucrose relative to untreated controls, and is accompanied by a corresponding rise in the levels or activities of the relevant terpene cyclases as determined by in vitro assay using labeled acyclic precursors. The results indicate that juvenile P. contorta responds to infection and biotic elicitors much like the mature tree, and they suggest that the Pinaceae possess a mechanism for elicitor recognition and induced defense similar to that of other higher plants.
Optimal Seat Suspension Design Based on Minimum “Simulated Subjective Response” (1997)

This work addresses a method for improving vertical whole body vibration isolation through optimal seat suspension design. The primary thrusts of this investigation are: (1) the development of a simple model that captures the essential dynamics of a seated human exposed to vertical vibration, (2) the selection and evaluation of several standards for assessing human sensitivity to vertical vibration, and (3) the determination of the seat suspension parameters that minimize these standards to yield optimal vibration isolation. Results show that the optimal seat and cushion damping coefficients depend very much on the selection of the vibration sensitivity standard and on the lower bound of the stiffnesses used in the constrained optimization procedure. In all cases, however, the optimal seat damping obtained here is significantly larger (by than a factor of 10) than that obtained using existing seat suspension design methods or from previous optimal suspension studies. This research also indicates that the existing means of assessing vibration in suspension design (ISO 7096) requires modification.
Electron Capture Dissociation in a Branched Radio-Frequency Ion Trap (2014)

We have developed a high-throughput electron capture dissociation (ECD) device coupled to a quadrupole time-of-flight mass spectrometer using novel branched radio frequency ion trap architecture. With this device, a low-energy electron beam can be injected orthogonally into the analytical ion beam with independent control of both the ion and electron beams. While ions and electrons can interact in a "flow-through" mode, we observed a large enhancement in ECD efficiency by introducing a short ion trapping period at the region of ion and electron beam intersection. This simultaneous trapping mode still provides up to five ECD spectra per second while operating in an information-dependent acquisition workflow. Coupled to liquid chromatography (LC), this LC-ECD workflow provides good sequence coverage for both trypsin and Lys C digests of bovine serum albumin, providing ECD spectra for doubly charged precursor ions with very good efficiency.