gebhart/patrepeval huggingface dataset:
Temporal integration of multiple silhouette-based body-part hypotheses (2005)

A method for temporally integrating appearance-based body-part labelling is presented. We begin by modifying the silhouette labelling method of Ghost (Haritaoglu, Harwood, and Davis. 1998); that system first determines which posture best describes the person currently and then uses posture-specific heuristics to generate labels for head, hands, and feet. Our approach is to assign a posture probability and then estimate body part locations for all possible postures. Next we temporally integrate these estimates by finding a best path through the posture-time lattice. A density-sampling propagation approach is used that allows us to model the multiple hypotheses resulting from consideration of different postures. We show quantitative and qualitative results where the temporal integration solution improves the instantaneous estimates. This method can be applied to any system that inherently has multiple methods of asserting instantaneous properties but from which a temporally coherent interpretation is desired.
Novel PEGylated Nanoassemblies Made of Self‐Assembled Squalenoyl Nucleoside Analogues (2008)

Abstract This study describes a new simple method to obtain high loading of anticancer or antiviral nucleoside analogues into “stealth” poly(ethylene glycol) (PEG)‐coated nanoassemblies. These nanodevices are obtained by co‐nanoprecipitation in water of (i) squalenoyl prodrugs obtained by the bioconjugation of the natural lipid squalene with either the anticancer drug gemcitabine (Gem‐Sq) or the antiviral drug deoxycytidine (ddC‐Sq) with (ii) a PEG derivative of either cholesterol (Chol‐PEG) or squalene (Sq‐PEG). It was found that both PEG derivatives (Chol‐PEG or Sq‐PEG) were efficiently incorporated in the resulting composite nanoassemblies (CNAs), as shown by radioactivity studies, Zeta potential determination, and size measurements. Optimal compositions were defined for each PEG derivative to ensure the best stability in water and in buffer solutions. X‐ray diffraction and electron microscopy investigations revealed that depending on the structure of the squalenoyl nucleoside analogue used (Gem‐Sq or ddC‐Sq), these nanoassemblies might be toroids or cubosomes. Following PEGylation, the Gem‐Sq nanoassemblies displayed superior in vitro anticancer activity on gemcitabine‐resistant leukemia L1210 10K cells than either their non‐PEGylated counterparts or gemcitabine alone.
Smart 3D video coding (2012)

In this paper we explore a method to encode/decode multiview textures and associated supplementary data (depth map as an example) together in a single bitstream. Least significant bit (LSB) of last two levels in each transform block has been modified according to the depth encoded bits, thus resulting in very minimal loss in PSNR of textures (0.1 - 0.5dB) with overall bitrate gain of about 13% for natural scenes. The remaining encoded information have been inserted after the slice NAL of corresponding texture ensuring backward compatibility and correct extraction and decoding by a modified decoder. Benchmarking results in terms of compression efficiency and quality on HD sequences have been reported to explore further the viability of using this technique for Free Viewpoint Video (FVV) or 3DV use cases. Experiments are also carried out to evaluate subjective quality of the synthesized views.
Assessment of biofeedback rehabilitation in post-stroke patients combining fMRI and gait analysis: a case study (2014)

Our findings showed that this methodology allows evaluation of the relationship between alterations in gait and brain activation of a post-stroke patient. Such methodology, if applied on a larger sample subjects, could provide information about the specific motor area involved in a rehabilitation treatment.
Vectorial calibration of superconducting magnets with a quantum magnetic sensor (2020)

Cryogenic vector magnet systems make it possible to study the anisotropic magnetic properties of materials without mechanically rotating the sample but by electrically tilting and turning the magnetic field. Vector magnetic fields generated inside superconducting vector magnets are generally measured with three Hall sensors. These three probes must be calibrated over a range of temperatures, and the temperature-dependent calibrations cannot be easily carried out inside an already magnetized superconducting magnet because of remaining magnetic fields. A single magnetometer based on an ensemble of nitrogen vacancy (NV) centers in diamond is proposed to overcome these limitations. The quenching of the photoluminescence intensity emitted by NV centers can determine the field in the remanent state of the solenoids and allows an easy and fast canceling of the residual magnetic field. Once the field is reset to zero, the calibration of this magnetometer can be performed in situ by a single measurement of an optically detected magnetic resonance spectrum. Thereby, these magnetometers do not require any additional temperature-dependent calibrations outside the magnet and offer the possibility to measure vector magnetic fields in three dimensions with a single sensor. Its axial alignment is given by the crystal structure of the diamond host, which increases the accuracy of the field orientation measured with this sensor, compared to the classical arrangement of three Hall sensors. It is foreseeable that the magnetometer described here has the potential to be applied in various fields in the future, such as the characterization of ferromagnetic core solenoids or other magnetic arrangements.
Crystalline polyester for low energy fusing with high charging ability (2010)

In recent years, environmental concerns and energy costs have created a need for lower energy consumption in the fusing systems of printers and copiers. To develop toner for low-energy fusing systems, we are investigating crystalline polyester (C-PES). Toner made from amorphous polyester (A-PES) and C-PES with annealing process shows good fusing ability and durability, as already reported by Fukuri et al. in NIP24. But charging ability of aliphatic C-PES was insufficient because of its monomer structure. In this paper, we report a study to achieve high charging ability by changing the monomer of C-PES from aliphatic diol to aromatic diol. Furthermore, crystallinity of aromatic C-PES can be controlled by adding another monomer which disturbs the symmetrical structure of C-PES. It was observed that the crystal size of aromatic C-PES becomes smaller in the toner, as the amount of another monomer increases. Therefore melting point of C-PES can be decreased. As a result, low energy fusible toner with high charging ability can be obtained.
A novel microchannel-based device to capture and analyze circulating tumor cells (CTCs) of breast cancer (2014)

Circulating tumor cells (CTCs) have been shown in many studies as a possible biomarker for metastasis and may be instrumental for the spread of the disease. Despite advances in CTC capturing technologies, the low frequency of CTCs in cancer patients and the heterogeneity of the CTCs have limited the wide application of the technology in clinic. In this study, we investigated a novel microfluidic technology that uses a size- and deformability-based capture system to characterize CTCs. This unique platform not only allows flexibility in the selection of antibody markers but also segregates the CTCs in their own chambers, thus, enabling morphological, immunological and genetic characterization of each CTC at the single cell level. In this study, different breast cancer cell lines including MCF7, MDA-MB-231 and SKBR3, as well as a panel of breast cancer biomarkers were used to test the device. The technology can capture a wide range of cells with high reproducibility. The capturing efficiency of the cells is greater than 80%. In addition, the background of leukocytes is minimized because individual cells are segregated in their own chambers. The device captured both epithelial cancer cells such as MCF7 and SKBR3 and mesenchymal cells such as MDA-MB-231. Immunostaining of the captured cells on the microchannel device suggests that a panel of breast cancer biomarkers can be used to further characterize differential expression of the captured cells.
The Tainted Heparin Story: An Update (2009)

Recently, certain batches of heparin have been associated with an acute, rapid onset of serious side-effects indicative of allergic-type reactions. These reports generated significant concern regarding the possible presence of a dangerous contaminant within heparin and highlighted the need to re-assess the purity criteria of heparin preparations for clinical use. Given the nature of the array of all possible contaminants, traditional screening tests cannot safely differentiate between contaminated and uncontaminated heparin preparations. Mono- and bi-dimensional NMR spectroscopy are powerful techniques that are able to detect and quantify a wide variety of potential sulfated polysaccharide contaminants. As such, these techniques are powerful tools for the analysis and assessment of heparin preparations.
Neuromodulation of Dorsal Root Ganglia (2020)

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Non‐orthogonal multiple access without channel state information for similar channel conditions (2019)

A downlink non‐orthogonal multiple access with QPSK input constellations based on virtual channel optimisation is presented to address the similar channel conditions scenario. The novel idea is to construct a uniquely decodable sum constellation by maximising the minimum Euclidean distance among the points of the superposed constellation. An optimal angle difference is derived to make the proposed scheme easy to implement. With a fixed angle pair setup, a non‐orthogonal multiple access system without the knowledge of channel state information is proposed. Simulation results are provided to demonstrate the performance of the proposed scheme.
Generation of a Focused Poly(amino ether) Library: Polymer-mediated Transgene Delivery and Gold-Nanorod based Theranostic Systems (2012)

A focused library of twenty-one cationic poly(amino ethers) was synthesized following ring-opening polymerization of two diglycidyl ethers by different oligoamines. The polymers were screened in parallel for plasmid DNA (pDNA) delivery, and transgene expression efficacies of individual polymers were compared to those of 25 kDa polyethylenimine (PEI), a current standard for polymer-mediated transgene delivery. Seven lead polymers that demonstrated higher transgene expression than PEI in pancreatic and prostate cancer cells lines were identified from the screen. All seven lead polymers showed highest transgene expression at a polymer:pDNA weight ratio of 5:1 in the MIA PaCa-2 pancreatic cancer cell line. Among the conditions studied, transgene expression efficacy correlated with minimal polymer cytotoxicity but not polyplex sizes. In addition, this study indicated that methylene spacing between amine centers in the monomers, amine content, and molecular weight of the polymers are all significant factors and should be considered when designing polymers for transgene delivery. A lead effective polymer was employed for coating gold nanorods, leading to theranostic nanoassemblies that possess combined transgene delivery and optical imaging capabilities, leading to potential theranostic systems.
1653: Safety and Efficacy of Partial Nephrectomy for all T1 Tumors Based on an International Multicenter Experience (2004)

You have accessJournal of UrologyTuesday, May 11, 2004, 1:00 - 3:00 pm1 Apr 20041653: Safety and Efficacy of Partial Nephrectomy for all T1 Tumors Based on an International Multicenter Experience Jean-Jacques Patard, Oleg Shvarts, Allan J. Pantuck, Vincenzo Ficarra, Hyung L. Kim, Luca Cindolo, Ken Han, Alexandre De La Taille, Jacques Tostain, Walter Artibani, ClementClaude Abbou, Bernard Lobel, Dominique Chopin, Franfois Guille, Robert A. Figlin, Peter Mulders, and Arie S. Belldegrun Jean-Jacques PatardJean-Jacques Patard More articles by this author , Oleg ShvartsOleg Shvarts More articles by this author , Allan J. PantuckAllan J. Pantuck More articles by this author , Vincenzo FicarraVincenzo Ficarra More articles by this author , Hyung L. KimHyung L. Kim More articles by this author , Luca CindoloLuca Cindolo More articles by this author , Ken HanKen Han More articles by this author , Alexandre De La TailleAlexandre De La Taille More articles by this author , Jacques TostainJacques Tostain More articles by this author , Walter ArtibaniWalter Artibani More articles by this author , ClementClaude AbbouClementClaude Abbou More articles by this author , Bernard LobelBernard Lobel More articles by this author , Dominique ChopinDominique Chopin More articles by this author , Franfois GuilleFranfois Guille More articles by this author , Robert A. FiglinRobert A. Figlin More articles by this author , Peter MuldersPeter Mulders More articles by this author , and Arie S. BelldegrunArie S. Belldegrun More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)38861-XAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1653: Safety and Efficacy of Partial Nephrectomy for all T1 Tumors Based on an International Multicenter Experience." The Journal of Urology, 171(4S), p. 437 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 171Issue 4SApril 2004Page: 437 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Jean-Jacques Patard More articles by this author Oleg Shvarts More articles by this author Allan J. Pantuck More articles by this author Vincenzo Ficarra More articles by this author Hyung L. Kim More articles by this author Luca Cindolo More articles by this author Ken Han More articles by this author Alexandre De La Taille More articles by this author Jacques Tostain More articles by this author Walter Artibani More articles by this author ClementClaude Abbou More articles by this author Bernard Lobel More articles by this author Dominique Chopin More articles by this author Franfois Guille More articles by this author Robert A. Figlin More articles by this author Peter Mulders More articles by this author Arie S. Belldegrun More articles by this author Expand All Advertisement PDF DownloadLoading ...
Ureteral Stenting During Extracorporeal Shock Wave Lithotripsy: Help or Hindrance? (1989)

We retrospectively reviewed the outcome of extracorporeal shock wave lithotripsy in patients with renal calculi less than 3 cm. in size who were treated at a large multi-user lithotripsy center. Patients in whom indwelling ureteral stents were placed before lithotripsy treatment were subjected to higher levels of total power (shocks times voltage), yet the rate free of stones did not differ from those treated without a stent. In addition, the patients with internal ureteral stents experienced a significantly higher incidence of urinary urgency (43 versus 25 per cent) and hematuria (40 versus 23 per cent) than nonstented patients, respectively (p less than 0.05). Also, the duration of bladder discomfort was longer for stented patients (26 versus 13 per cent) as was the duration of urinary frequency (31 versus 16 per cent), compared to nonstented patients (p less than 0.05). The results suggest that use of an indwelling ureteral stent may not contribute to a higher rate free of stones for the treatment of small to medium sized renal calculi and, in fact, it may make the treatment more uncomfortable for the patient than performing lithotripsy without ureteral stenting. Of course, in selected cases (solitary kidney, large stone burden and aid in stone localization) ureteral stenting has a useful adjunctive role in extracorporeal shock wave lithotripsy.
Culture human mesenchymal stem cells with calcium phosphate cement scaffolds for bone repair (2010)

Because of its moldability and excellent osteoconductivity, calcium phosphate cement (CPC) is highly promising for craniofacial and orthopedic applications. The objectives of this study were to investigate the response of human mesenchymal stem cells (hMSCs) to a high-strength CPC-chitosan scaffold and to examine cell proliferation and osteogenic differentiation. hMSCs were seeded onto CPC-chitosan composite, CPC control, and tissue culture polystyrene (TCPS). Alkaline phosphatase activity (ALP) and mineralization of hMSCs were measured. CPC-chitosan had a flexural strength (mean + or - SD; n = 5) of (19.5 + or - 1.4) MPa, higher than (8.0 + or - 1.4) MPa of CPC control (p < 0.05). The percentage of live hMSCs on CPC-chitosan was (90.5 + or - 1.3)% at 8 days, matching (90.7 + or - 3.8)% of CPC control (p > 0.1). The CPC-chitosan surface area covered by the attached hMSCs increased from (51 + or - 11)% at 1 day to (90 + or - 4)% at 8 days (p < 0.05), matching those of CPC control (p > 0.1). Hence, the CPC strength was significantly increased via chitosan without compromising the hMSC response. At 8 days, there was a significant increase in ALP of cells in osteogenic media (10.99 + or - 0.93) [(mM pNpp/min)/(microg DNA)] versus control media (3.62 + or - 0.40) (p < 0.05). hMSCs in osteogenic media exhibited greater mineralization area of (47.5 + or - 19.7)% compared with (6.1 + or - 2.3)% in control medium on TCPS (p < 0.05). In conclusion, hMSCs showed excellent attachment and viability on the strong and tough CPC-chitosan scaffold, matching the hMSC response on CPC control. hMSCs were successfully differentiated down the osteogenic lineage. Hence, the strong, in situ hardening CPC-chitosan scaffold may be useful as a moderate load-bearing vehicle to deliver hMSCs for maxillofacial and orthopedic bone tissue engineering.
Exosome-Mediated Crosstalk between Keratinocytes and Macrophages in Cutaneous Wound Healing (2020)

Bidirectional cell–cell communication involving exosome-borne cargo such as miRNA has emerged as a critical mechanism for wound healing. Unlike other shedding vesicles, exosomes selectively package...
PET Imaging Innovation by DOI Detectors (2016)

Positron emission tomography (PET) plays important roles in cancer diagnosis, neuroimaging, and molecular imaging research. However potential points remain for which big improvements could be made, including spatial resolution, sensitivity, and manufacturing costs. Depth-of-interaction (DOI) measurement in the radiation sensor will be a key technology to get any significant improvement in sensitivity while maintaining high spatial resolution. We have developed four-layered DOI detectors based on our original light-sharing method. DOI measurement also has a potential to expand PET application fields because it allows for more flexible detector arrangement. As an example, we are developing the world’s first, open-type PET geometry, “OpenPET,” which is expected to lead to PET imaging during treatment. The DOI detector itself continues to evolve with the help of recently developed semiconductor photodetectors, often referred to as silicon photomultipliers (SiPMs). We are developing a SiPM-based DOI detector “X’tal cube” to achieve sub-mm spatial resolution, which is reaching the theoretical limitation of PET imaging. Innovation of SiPMs encourages our development of PET/MRI, which is attracting great notice in terms of smaller radiation exposure and better contract in soft tissues compared with current PET/CT.
Effects of Latency and Spatial Jitter on 2D and 3D Pointing (2009)

We investigate the effects of input device latency and spatial jitter on 2D pointing tasks and a 3D movement. First, we characterize jitter and latency in a 3D tracking device and an optical mouse used for baseline comparison. We present an experiment based on ISO 9241-9, which measures performance of pointing devices. We added latency and jitter to the mouse and compared it to a 3D tracker. Results indicate that latency has a stronger effect on performance than small spatial jitter. A second experiment found that erratic jitter "spikes" can affect 3D movement performance.
Langerhans cell antigen capture through tight junctions confers preemptive immunity in experimental staphylococcal scalded skin syndrome (2011)

Epidermal Langerhans cells (LCs) extend dendrites through tight junctions (TJs) to survey the skin surface, but their immunological contribution in vivo remains elusive. We show that LCs were essential for inducing IgG(1) responses to patch-immunized ovalbumin in mice that lacked skin dendritic cell subsets. The significance of LC-induced humoral responses was demonstrated in a mouse model of staphylococcal scalded skin syndrome (SSSS), a severe blistering disease in which the desmosomal protein Dsg1 (desmoglein1) is cleaved by Staphylococcus aureus-derived exfoliative toxin (ET). Importantly, ET did not penetrate TJs, and patch immunization did not alter epidermal integrity. Nevertheless, neutralizing anti-ET IgG(1) was induced after patch immunization and abolished upon LC depletion, indicating that antigen capture through TJs by LCs induced humoral immunity. Strikingly, the ET-patched mice were protected from developing SSSS after intraperitoneal ET challenge, whereas LC-depleted mice were susceptible to SSSS, demonstrating a vital role for LC-induced IgG(1) in systemic defense against circulating toxin in vivo. Therefore, LCs elicit humoral immunity to antigens that have not yet violated the epidermal barrier, providing preemptive immunity against potentially pathogenic skin microbes. Targeting this immunological process confers protection with minimal invasiveness and should have a marked impact on future strategies for development of percutaneous vaccines.
The value of system level integration (2003)

Summary form only given. Multi-Layer Switch (MLS) architectures leverage recent advances in optical transport reach, all optical switching, conventional electrical switching, and control plane standards to significantly reduce both capital and operational expenditures for next generation network designs. Although each is valuable as a stand-alone technology, combined they provide a number of additional benefits that can only be achieved when fully integrated. Most notable are elimination of back-to-back intra-office interfaces and back-to-back transponders at signal by-pass nodes while still providing the ability to groom and aggregate subwavelength traffic when necessary. Along with the reduced equipment count comes savings in floor space, power, sparing, network management, fibre congestion, and operational costs. There is also an inherent stability and improved network utilization obtained by having the same control plane agent responsible for all three layers that is not possible with discrete machines even if they are from the same vendor. Consequently, all four emerging technologies must be employed together to fully realize the promise of true optical networking and leverage the value each brings.
Electron/Ion Transport Enhancer in High Capacity Li-Ion Battery Anodes (2016)

Magnetite (Fe3O4) was used as a model high capacity metal oxide active material to demonstrate advantages derived from consideration of both electron and ion transport in the design of composite battery electrodes. The conjugated polymer, poly[3-(potassium-4-butanoate) thiophene] (PPBT), was introduced as a binder component, while polyethylene glycol (PEG) was coated onto the surface of Fe3O4 nanoparticles. The introduction of PEG reduced aggregate size, enabled effective dispersion of the active materials and facilitated ionic conduction. As a binder for the composite electrode, PPBT underwent electrochemical doping which enabled the formation of effective electrical bridges between the carbon and Fe3O4 components, allowing for more efficient electron transport. Additionally, the PPBT carboxylic moieties effect a porous structure, and stable electrode performance. The methodical consideration of both enhanced electron and ion transport by introducing a carboxylated PPBT binder and PEG surface treatment leads to effectively reduced electrode resistance, which improved cycle life performance and rate capabilities.