gebhart/patrepeval huggingface dataset:
Robust and consistent pilot designs for frequency offset estimation in MIMO OFDM systems (2008)

This paper presents pilot designs for consistent frequency offset estimation of MIMO OFDM systems in frequency selective fading channels. We derive the sufficient consistency condition for the pilots in MIMO OFDM systems to yield unambiguous estimation, and present corresponding consistent pilot designs. We discuss robustness of the frequency offset estimation against outliers at low to moderate SNR values and present an efficient criterion to choose robust and consistent pilots. Furthermore, we develop pilot designs which satisfy both consistency over a limited frequency offset estimation range and the optimal channel estimation condition in MIMO OFDM systems. Simulation results corroborate that both the consistent pilot design condition and the robustness criterion are efficient in choosing pilot patterns yielding better frequency offset estimation performance.
New Environmentally Friendly Solution for Iron Scale Removal (2020)

Iron sulfide scale is considered a big issue in the oil and gas industry and a very common problem in daily operation bases. The iron scale severely affects the production rates and field operation, as the iron scale precipitation on the well completion tools or the pipelines` inner surfaces will decrease the diameter size and cause flow restriction. Failure of the downhole completions tools will decrease the well production and it might require workover operations to cure the problem. Such workover operations add an extra cost. In addition, the iron scale is a big problem for the petroleum reservoirs as it changes the rock wettability from water-wet to oil-wet. Many studies and researches were performed to find an economical and efficient removal for the iron sulfide scale. The main objective of this study is to find a new environmentally chemical solution to be used for iron sulfide scale removal. Additionally, to study the new fluid performance in terms of solubility for an iron scale (field sample), corrosion effect, and biodegradability for environmentally safe use. Lab solubility tests had been done at different times and concentrations to get the optimum time and concentration that provides the optimum iron scale solubility rate. Corrosion tests were performed to determine the corrosion rates for the new chemical and the results were compared with other commercial chemicals for iron scale removal. The results from the study showed excellent performance for the scale solubility and for the corrosion rates. The iron scale solubility showed 82 % after 6 hours at 125°C for the static condition. In addition, the solubility rates ranged from 77% after 2 hours to 81% after 24 hours along the 24 hours of different time steps. The corrosion rate is 0.04 lb/ft2 which is considered a small rate compared to other used commercial fluids. The research outcomes provide an efficient chemical for iron scale removal that is environmentally safe to be used in the oil and gas fields. The new environmentally friendly acid system NEFAS provides very good performance for iron scale removal, with a lower cost than commercial chemicals. Furthermore, the new system is a biodegradable and environmentally safe system.
Rseg—an R package to optimize segmentation of SNP array data (2010)

The R package, Rseg, is available at: http://www.cs.au.dk/~plamy/Rseg/ and runs on Linux and MS-Windows.
An Efficient Ultra-Tight GPS/RISS Integrated System for Challenging Navigation Environments (2020)

The Global Positioning System (GPS) provides an accurate navigation solution in the open sky. However, in some environments such as urban areas or in the presence of signal jamming, GPS signals cannot be easily tracked since they could be harshly attenuated or entirely blocked. This often requires the GPS receiver to go into a signal re-acquisition phase for the corresponding satellite. To avoid the intensive computations necessary for the signal re-lock in a GPS receiver, a robust signal-tracking mechanism that can hold and/or rapidly re-lock on the signals and keep track of their dynamics becomes a necessity. This paper augments a vector-based GPS signal tracking system with a Reduced Inertial Sensor System (RISS) to produce a new ultra-tight GPS/INS integrated system that enhances receivers’ tracking robustness and sensitivity in challenging navigation environments. The introduced system is simple, efficient, reliable, yet inexpensive. To challenge the proposed method with real jamming conditions, real experiment work was conducted inside the Anechoic Chamber room at the Royal Military College of Canada (RMC). The Spirent GSS6700 signal simulator was used to generate GPS signals, and an INS Simulator is used for simulating the inertial measurement unit (IMU) to generate the corresponding trajectory raw data. The NEAT jammer, by NovAtel, was used to generate real jamming signals. Results show a good performance of the proposed method under real signal jamming conditions.
Interfacial Engineering by Atomic Layer Deposition for Highly Durable and Safe Lithium-Ion Batteries (2010)

Abstract not Available.
Sequence stratigraphy as an inter-disciplinary tool for karst network forecast. Multiphase and multiprocess karst genesis in the Urgonian Formation (2019)

International audience
Local versus global torque optimization of redundant manipulators (2005)

This paper compares local and global optimization methods for minimizing torque loading at the joints of a redundant manipulator in a least squares sense. Simulations show that the local methods show an unexpected instability for relatively long trajectories. The global method, however, was able to find a stable solution which outperformed the local algorithms at all times.
Leakage Bounds for Gaussian Side Channels. (2017)

In recent years, many leakage-resilient schemes have been published. These schemes guarantee security against side-channel attacks given bounded leakage of the underlying primitive. However, it is a challenging task to reliably determine these leakage bounds from physical properties.
Coupled Electrooxidation and Electrical Conduction in a Single Gold Nanowire (2008)

The resistance, R, of single gold nanowires was measured in situ during electrooxidation in aqueous 0.10 M sulfuric acid. Electrooxidation caused the formation of a gold oxide that is approximately 0.8 monolayers (ML) in thickness at +1.1 V vs saturated mercurous sulfate reference electrode (MSE) based upon coulometry and ex situ X-ray photoelectron spectroscopic analysis. As the gold nanowires were electrooxidized, R increased by an amount that depended on the wire thickness, ranging from Delta R/ R 0.10V = 14% for a 63 nm (h) x 200 nm (w) wire to 57% for an 18 nm (h) x 95 nm (w) wire at +1.1 V. These nanowires were millimeters in total length, but just 46 microm lengths were exposed to the electrolyte solution. The oxidation process and the accompanying increase in R were reversible: Reduction of the oxide at +0.10 V resulted in recovery of the reduced wire R except for a small resistance offset caused by the dissolution of approximately 0.4 ML of gold during each oxidation/reduction cycle. The measured increase in R during oxidation exceeds by a factor of 4 the predicted increases in R associated with the reduction in cross-sectional area of the nanowire and the expected decrease in the specular scattering parameter, p, at the gold-oxide interface at wire surfaces. We propose that this anomalous increase in R is caused by infiltration of the oxide into the nanowire at grain boundaries.
High Temperature DBR Laser Diodes for Quantum Sensing Applications (2021)

Next-generation portable PNT systems using Alkali-atom and cold-atom physics require robust low SWaP+C laser diode sources that operate under a wide range of environmental conditions. Photodigm has developed high operating temperature (HOT) Distributed Bragg Reflector (DBR) lasers at key Alkali-atom wavelengths for quantum sensing applications.
The Accuracy of Cone Frustum Machined by Five-axis Machine Tool with Tilting Table (2008)

The cone frustum machining test prescribed in NAS979 is only one method that is used in world wide to evaluate the machining accuracy of five-axis machine tools. The issue is that the test parameters are not defined in the machining by using five-axis machine tools with tilting table. The motion of each axis depends on the location of a workpiece, and the workpiece location is an important factor for the evaluation. In this paper, the influence of the workpiece location for five-axis machine tools with tilting table is analyzed, and it is shown that the accuracy of machined cone frustum varies due to the workpiece location and the influence of the geometric errors in the five-axis machine tool. The proper location to evaluate the geometric errors is also proposed.
Atomic Force Microscopy of Instabilities and Reorganization of Langmuir-Blodgett Films (1998)

The atomic force microscope was used to show that Langmuir-Blodgett films are unstable to reorganization via a folding mechanism by which uniformly thick films spontaneously form holes and multilayer steps. These bilayer step defects originate at isolated sites and quickly spread to cover the entire film. The defects retain the sixfold symmetry of the underlying molecular lattice; after sufficient time, straight edges begin to form and the entire film is comprised of high islands with straight edges aligned with sixfold symmetry. The kinetics of the reorganization depend strongly on the chain length of the fatty acid used and the nature of the substrate. The results suggest that the reorganization is driven by an interconversion of strained, asymmetric monolayers to unstrained, centrosymmetric bilayers.
Down-regulation of homeobox gene GBX2 expression inhibits human prostate cancer clonogenic ability and tumorigenicity. (1998)

Previously, we have demonstrated that GBX genes, a homeobox-containing human family of DNA-binding transcription factors consisting of GBX1 and GBX2, are overexpressed in a panel of human prostatic cancer cell lines (ie., TSU-pr1, PC3, DU145, and LNCaP) compared to normal prostate. In the present studies, specific primer sets were designed for reverse transcription-PCR detection of the expression of GBX1 versus GBX2 in human prostate cancer. These studies demonstrated that the GBX2 gene, but not the GBX1 gene, is consistently overexpressed in this panel of human prostate cancer cell lines compared to normal human prostate. Using a quantitative-competitive PCR analysis, GBX2 mRNA was expressed as 3 x 10(3) copies/microg RNA in normal prostate tissue and 4 x 10(4) copies/microg RNA in the immortalized normal neonatal prostate epithelial cell line 267B-1, as compared to 6 x 10(5), 5 x 10(5), 3 x 10(5), and 1 x 10(5) copies/microg RNA in TSU-pr1, DU145, LNCaP, and PC3 prostate cancer cell lines, respectively. To examine the importance of GBX2 expression for prostate cancer malignancy, GBX2-overexpressing TSU-pr1 and PC3 human prostatic cancer cells were transfected with a eukaryotic expression vector containing an antisense GBX2 homeobox domain cDNA. Stable transfectant clones with 5-10-fold decreased levels of GBX2 mRNA expression were obtained. When tested in vitro, the clonogenic ability of the GBX2 antisense transfectants was reduced by approximately 50% in both cell lines. When implanted s.c. into nude mice, the tumorigenicity of the antisense GBX2 transfectants from both human prostatic cancer cell lines was inhibited by more than 70% compared to the parental cells. These results suggest that expression of GBX2 gene is required for malignant growth of human prostate cells.
Epidermal Growth Factor Receptor as Target for Perioperative Elimination of Circulating Colorectal Cancer Cells (2022)

Surgical resection of the tumor is the primary treatment of colorectal cancer patients. However, we previously demonstrated that abdominal surgery promotes the adherence of circulating tumor cells (CTC) in the liver and subsequent liver metastasis development. Importantly, preoperative treatment with specific tumor-targeting monoclonal antibodies (mAb) prevented surgery-induced liver metastasis development in rats. This study investigated whether the epidermal growth factor receptor (EGFR) represents a suitable target for preoperative antibody treatment of colorectal cancer patients undergoing surgery. The majority of patients with resectable colorectal liver metastases were shown to have EGFR + CTCs. Three different anti-EGFR mAbs (cetuximab, zalutumumab, and panitumumab) were equally efficient in the opsonization of tumor cell lines. Additionally, all three mAbs induced antibody-dependent cellular phagocytosis (ADCP) of tumor cells by macrophages at low antibody concentrations <i>in vitro</i>, independent of mutations in EGFR signaling pathways. The plasma of cetuximab-treated patients efficiently opsonized tumor cells <i>ex vivo</i> and induced phagocytosis. Furthermore, neither proliferation nor migration of epithelial cells was affected <i>in vitro</i>, supporting that wound healing will not be hampered by treatment with low anti-EGFR mAb concentrations. These data support the use of a low dose of anti-EGFR mAbs prior to resection of the tumor to eliminate CTCs without interfering with the healing of the anastomosis. Ultimately, this may reduce the risk of metastasis development, consequently improving long-term patient outcome significantly.
Synergistic antiallodynic effects of spinal morphine with ketorolac and selective COX1- and COX2-inhibitors in nerve-injured rats ☆ (1999)

The possible role of spinal prostanoids in the tactile allodynia and thermal hyperalgesia associated with an experimental model of neuropathic pain was investigated. Neuropathic pain was induced by tight ligation of the L5 and L6 spinal nerves. Tactile allodynia was assessed 7 days after the surgery by measuring hindpaw withdrawal threshold to probing with von Frey filaments. Thermal hyperalgesia and nociception were determined by the 52 degrees C warm-water tail-flick test and by applying radiant heat to the plantar aspect of the hindpaw ipsilateral to the ligation. Minimal antiallodynic effect was produced by intrathecal (i.th.) administration of ketorolac or morphine up to the highest testable dose (100 microg) or by the (R)- or (S)-enantiomers of ketorolac (up to 6 microg) when administered alone. However, i.th. administration of a fixed ratio (1:1) of morphine plus racemic ketorolac or of morphine plus the (S)-enantiomer of ketorolac (S-ketorolac) produced a dose- and time-related antiallodynic effect: ED50 114 +/- 35.9 microg (total dose) for morphine plus ketorolac and 70.5 +/- 21.0 microg (total dose) for morphine plus S-ketorolac. The combination of i.th. morphine plus the (R)-enantiomer of ketorolac (R-ketorolac) (up to 200 microg total dose) was without effect. Similar antiallodynic activity was obtained for the co-administration of i.th. morphine and intravenous (i.v.) racemic ketorolac. In order to investigate the role of cyclooxygenase (COX) isozymes, relatively selective COX1 (piroxicam) and COX2 N-[2-cyclohexyloxy-4-nitrophenyl] metanesulfonamide (NS-398) inhibitors were administered i.th. (60 microg) alone or together with i.th. morphine. Piroxicam, NS-398, morphine and vehicle (90% DMSO) were without significant antiallodynic effect when administered alone, but moderate antiallodynic effects were produced by i.th. administration of fixed ratio (1:1) combinations of morphine with 60 microg each (highest soluble dose) of piroxicam (%MPE = 40.8 +/- 10.2) or NS-398 (%MPE = 32.4 +/- 9.5). Further, the combined i.th. administration of morphine, piroxicam and NS-398 in fixed 1:1:1 ratio (60 microg each) resulted in a supraadditive antiallodynic effect (%MPE = 70.4 +/- 10.8). Finally, morphine, but not ketorolac, given i.th. produced dose-dependent anti nociception in either the tail-flick or the paw-flick tests. However, there was no synergy between morphine and ketorolac against thermal nociception in either of the tests. These findings suggest that spinal prostanoids produced via both COX1 and COX2 pathways may play a role in neuropathic pain states and suggest the clinical utility of opioid plus COX-inhibitor combination therapy.
A Case of Primary Mediastinal Germ Cell Tumor Associated with Klinefelter's Syndrome (1996)

Klinefelter's syndrome is characterized by small testes, azoospermia, gynecomastia, and elevated levels of plasma gonadotropins in men with two or more X chromosomes. Previous investigators reported that patients with Klinefelter's syndrome are predisposed to the development of a non-seminomatous germ cell tumor in the mediastinum. It is suggested that this linkage may be due to the hormonal imbalance in Klinefelter's syndrome and consequently, the formation of dysgenetic germ cell and/or abnomal migration of germ cell. We report here a case of Klinefelter's syndrome in a 24-years-old man who was presented with anterior mediastinal mass. The clinical and laborarotory findings were compatible with Klinefelter's syndrome and he was found to have 47 XXY karyotype. Pathological findings for mediastinal mass revealed mixed germ cell tumor composed of mature cystic teratoma and endodermal sinus tumor. He was treated with cis-platin containing chemotherapy and followed up in partial remission.
A Peleja de Inácio da Catingueira e Romano da Mãe d’Água (2015)

Anthropos , Seite 119 - 124
Transcranial Photobiomodulation Improves Cognitive Performance in Young Healthy Adults: A Systematic Review and Meta-Analysis (2019)

<b><i>Background:</i></b> Transcranial photobiomodulation (t-PBM) is a noninvasive modality that may improve cognitive function in both healthy and diseased subjects. <b><i>Objective:</i></b> This systematic review and meta-analysis addresses the question of whether t-PBM improves cognitive function in healthy adults. <b><i>Methods:</i></b> We searched MEDLINE using PubMed, EMBASE, SCOPUS, Web of Science, and Cochrane Library up to March 2019. We also searched ProQuest and Google Scholar databases for unpublished material. The search was limited to articles on the procognitive effects of t-PBM in healthy adults. The initial search resulted in 871 studies, of which nine publications met our criteria for inclusion and exclusion. Seven studies were performed on young, healthy subjects (17-35 years), and two studies were conducted on older (≥49 years), normal subjects. A meta-analysis was performed on six full-text publications whose subjects were young adults. <b><i>Results:</i></b> t-PBM administration improved cognition-related outcomes by an 0.833 standardized mean difference (SMD; 95% confidence interval (CI): 0.458-1.209, 14 comparisons) in young, healthy participants. Funnel plotting revealed asymmetry, which was validated using Egger's (<i>p</i> = 0.030) and Begg's regression (<i>p</i> = 0.006) tests. However after reanalysis, this asymmetry disappeared in the attention subgroup, but not in the memory subgroup. The trim-and-fill analysis indicated two studies were lacking required data. Thus, the effect size was adjusted from an SMD of 0.761 (95% CI: 0.573-0.949) to 0.949 (0.779-1.120). The overall quality score of the studies was modest. <b><i>Conclusions:</i></b> We demonstrated a significant, beneficial effect of t-PBM on cognitive performance of young, healthy individuals; however, the heterogeneity of the data was high. This could be due to the modest quality or to the low number of included studies, or to the differences between the various subdomains assessed. These shortcomings should be meticulously addressed before concluding that t-PBM is a cognitive-enhancing intervention in healthy individuals.
Solid-state NMR evidence for inequivalent GvpA subunits in gas vesicles (2009)

Gas vesicles are organelles that provide buoyancy to the aquatic microorganisms that harbor them. The gas vesicle shell consists almost exclusively of the hydrophobic 70-residue protein GvpA, arranged in an ordered array. Solid-state NMR spectra of intact, collapsed gas vesicles from the cyanobacterium Anabaena flos-aquae show duplication of certain GvpA resonances, indicating that specific sites experience at least two different local environments. Interpretation of these results in terms of an asymmetric dimer repeat unit can reconcile otherwise conflicting features of the primary, secondary, tertiary and quaternary structures of the gas vesicle protein. In particular, the asymmetric dimer can explain how the hydrogen bonds in the β–sheet portion of the molecule can be oriented optimally for strength while promoting stabilizing aromatic and electrostatic side-chain interactions among highly conserved residues and creating a large hydrophobic surface suitable for preventing water condensation inside the vesicle.
Comparative Analysis of Modulation Techniques for Modular Multilevel Converters in Traction Drives (2018)

The spreading of electric vehicles led to a renewed interest for innovative traction drives. In this context, an electric traction drive based on a Modular Multilevel Converter and integrating batteries in each module has been recently proposed. This converter concentrates into a single unit, the control of the traction motors, the balancing and energy management of the battery cells and the vehicle recharge functions. By using different modulation techniques it is possible to optimize different aspects like efficiency or THD of output current and voltages. Performance and efficiency in balancing, traction and recharging operations have been analyzed for two modulation techniques: near level modulation and phase disposition PWM. The near level modulation reduces switching losses while the second one better follows voltage references reducing current THD and, consequently, conduction losses. In this paper an innovative modulation technique is proposed and its performance in terms of current THD and global losses are compared with the other two modulation strategies already proposed.
A<sub>2A</sub> Adenosine Receptor Agonist and PDE<sub>4</sub> Inhibition Delays Inflammation but Fails to Reduce Injury in Experimental Obstructive Nephropathy (2005)

A2A receptor activation and PDE4 inhibition transiently reduce renal macrophage infiltration, but do not ameliorate the renal response to UUO. We speculate that the persistent stimulus for inflammation triggered by UUO cannot be reversed by agents that suppress inflammatory cell activation alone.