gebhart/patrepeval huggingface dataset:
Diffractive optics in the Thomson Group (1998)

This paper deals with diffractive surfaces used in optical designs: fabricated devices operating over the infrared wavebands are detailed, and the means of manufacture within the Thomson Optronic Group are described.
Notice of Removal: High frequency row column addressed matrix array for volumetric ultrafast ultrasound imaging (2017)

Removed.
Effects of infection with Anguillicola crassus and simultaneous exposure with Cd and 3,3′,4,4′,5-pentachlorobiphenyl (PCB 126) on the levels of cortisol and glucose in European eel (Anguilla anguilla) (2005)

To investigate whether the stress response of European eels infected with Anguillicola crassus is influenced by environmental pollutants, experimentally infected eels were exposed to Cd and/or to 3,3', 4,4', 5-pentachlorobiphenyl (PCB 126). Serum cortisol and glucose concentrations of these eels were monitored over a period of 103 days and were compared with data from infected, unexposed eels as well as with data from uninfected eels. Additionally, the levels of cortisol were correlated with concentrations of Anguillicola-specific antibodies. All eels showed an initial increase of the cortisol levels until day 63. This general elevation of plasma cortisol is most likely due to handling stress, as all eels were repeatedly netted and afterwards inoculated with a feeding tube. At the end of the exposure period eels which were infected and those which were infected and simultaneously exposed to Cd and PCB showed significantly higher levels than the controls. The general course of serum glucose levels in eels resembled that of cortisol. Accordingly, Spearman correlation analysis revealed that an increase in serum cortisol concentrations is correlated with rising levels of glucose. With respect to immune-endocrine interactions a significant negative correlation between cortisol and anti-A. crassus antibodies was found. Our data show that A. crassus is the most potent stressor for European eels among the treatments tested within this study. This is important in terms of ecotoxicological studies as the main effects are caused by parasites rather than chemicals. Accordingly, effects of parasites on the physiological homeostasis of organisms must be considered in ecotoxicology. From the parasitological point of view our results suggest that probably as part of an unbalanced host-parasite interaction A. crassus evokes a strong cortisol response in A. anguilla, thereby suppressing the immune response which in turn enables the parasite to establish. The parasite-induced stress response in the newly adopted European eel might be one of the factors which contributes to the extremely effective colonizing strategy of A. crassus.
Performance Comparison of a Pretied Suture Knot With Three Conventional Arthroscopic Knots (2015)

The pre-tied knot offers equivalent or improved strength while having a smaller knot volume.
Inhibition of arterial thrombus formation in two canine models: comparison of ancrod, a fibrinogen-depleting agent, the thrombin-inhibitor r-hirudin, and the glycoprotein 11b/IIIa-receptor antagonist Ro 43-8857. (1995)

Inhibition of arterial thrombus formation by ancrod, a fibrinogen depleting agent isolated from a snake venom, r-hirudin, an inhibitor of thrombin-mediated fibrinogen cleavage, or the glycoprotein (GP)IIB/IIIa-receptor antagonist Ro 43-8857 interfering with fibrinogen binding to platelets, was evaluated in two canine models. As a marker of platelet-dependent thrombus formation, cyclic blood flow reductions (CFR) were induced in the left coronary artery (LAD) of mongrel dogs by mechanical injury of the endothelium combined with critical stenosis. In the second model CFRs were induced by thrombolysis of a copper coil-induced thrombus in the carotid artery. Blood flow rate during the reocclusion phase was used as an additional parameter of efficacy. The frequency of CFRs used a indicator of platelet aggregation and adhesion was significantly diminished by all treatments in both the carotid artery- and the LAD-model. In the LAD-model, following ancrod treatment, CFRs were correlated with plasma fibrinogen concentrations. Carotid artery blood flow after reperfusion, used as indicator of occlusive thrombus formation, rapidly declined to zero in the control group but remained at a high level after treatment with ancrod or r-hirudin. Ro 43-8857 at the selected dose improved flow rate only to a minor degree but prolonged the bleeding time from a mean value of 87.2 +/- 10.9 s (n = 24) to values > 300 s in 50% of the animals. Our results indicate that CFRs as indicator of platelet aggregation and adhesion are inhibited by either treatments. Blood flow as indicator of occlusive thrombus formation, however, is effectively improved by ancrod and r-hirudin only. Inhibition of fibrinogen binding to platelet GPIIb/IIIa receptors alone was found to be less potent antithrombotic principle in this model.
Supplementary Figure 7 from Discovery of a Mutant-Selective Covalent Inhibitor of EGFR that Overcomes T790M-Mediated Resistance in NSCLC (2023)

&lt;p&gt;Supplementary Figure 7 - PDF file 352K, H&amp;E and immunohistochemical (Ki67) staining of tumors derived from EGFR mutant GEM models&lt;/p&gt;
SiGe HBTs in 90nm BiCMOS technology demonstrating 300GHz/420GHz fT/fMAX through reduced Rb and Ccb parasitics (2013)

Scaling both the f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> and the f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MAX</sub> of SiGe HBTs is quite challenging due to the opposing physical device requirements for improving these figures of merit. In this paper, millisecond anneal techniques, low temperature silicide and low temperature contact processes are shown to be effective in reducing the base resistance. These processes when combined with a novel approach to address the collector-base capacitance are shown to produce high performance SiGe HBT devices which demonstrate operating frequencies of 300/420GHz f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">T</sub> /f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MAX</sub> . This is the first report of 90nm SiGe BICMOS with an f <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MAX</sub> exceeding 400GHz.
Mn2O3 Slurry Reuse for SiO2 Film CMP (2011)

Nowadays, reducing the amount of the used slurry waste is extremely important from an ecological point of view. Chemical mechanical polishing (CMP) slurry reuse enables us to drastically reduce the cost and waste of slurry. Many researches have studied on the reuse of conventional slurry [1, 2, 3, 4]. As the removal rate of the conventional slurry strongly depends on the solid concentration and the pH, the conventional slurry must be severely controlled during the reuse of slurry [1, 4, 5]. This makes it difficult to reuse the conventional slurry in manufacturing. In our prior work, we reported that Mn2O3 slurry can polish SiO2 film, while offering a high removal rate and the realization of pad-conditioning-free polish [6]. In this paper, we have studied on the reuse of Mn2O3 slurry by circulating slurry.
All Niobium Nitride Josephson Junction with Hydrogenated Amorphous Silicon Barrier and its Application to the Logic Circuit (1984)

Josephson tunnel junctions with all niobium nitride (NbN) electrodes were fabricated with sputtered amorphous silicon (a-Si:H) films as tunnel barriers whose surfaces are oxidized by an rf-plasma oxidation. The specific capacitance of the fabricated junction strongly decreased with increase in the thickness of the a-Si:H film. The specific capacitance of less than 4 µF/cm 2 was obtained for the a-Si:H thickness of about 2 nm. A logic circuit composed of four-junction logic (4JL) gates was fabricated using these junctions and was operated with the minimum logic delay of 9 ps/gate.
Synergistic anti‐tumor effect of paclitaxel with CRM197, an inhibitor of HB‐EGF, in ovarian cancer (2008)

Heparin-binding EGF-like growth factor (HB-EGF) plays a pivotal role in tumor growth and clinical outcomes in patients with ovarian cancer, leading to the validation of HB-EGF as a target for ovarian cancer therapy. In this study, we investigated the anti-tumor effects of paclitaxel, as an anti-cancer agent, and CRM197, as a specific inhibitor off HB-EGF, in ovarian cancer. Paclitaxel induced transient ERK activation and sustained activation of JNK and p38 MAPK through the ectodomain shedding of HB-EGF in SKOV3 cells. In addition, the overexpression of HB-EGF in paclitaxel-treated SKOV3 cells resulted in modulation of paclitaxel-evoked MAPK signaling, including marked activation of ERK and Akt, and minimized activation of JNK and p38 MAPK, indicating that HB-EGF is involved in drug sensitivity through the balance of anti-apoptotic and pro-apoptotic signals induced by paclitaxel. The combination of paclitaxel with CRM197 had an inhibitory effect on cell proliferation and enhanced apoptosis via the inhibition of ERK and Akt activation and the stimulation of p38 and JNK activation. More prominently, the administration of paclitaxel with CRM197 resulted in synergistic anti-tumor effects in SKOV3 cells and in SKOV3 cells overexpressing HB-EGF in xenografted mice. Accordingly, inhibitory agents against HB-EGF, such as CRM197, represent possible chemotherapeutic and chemosensitizing agents for ovarian cancer.
Automated Topology Processing for Conventional, Phasor-Assisted and Phasor-Only State Estimators (2012)

Although the “State Estimation” concept was established decades ago, it is still a cornerstone for developing advanced applications for real-time operation and control of transmission networks. Sta ...
Imaging cell clusters and tissue using learning tomography (2017)

We present an experimental comparison of optical tomography techniques: Learning Tomography (LT), an iterative method based on beam propagation model and diffraction tomography (DT) based Born and Rytov approximation. Imaging experiments were performed on yeast cells clusters fixed in a transparent agarose gel. In particular, we compare the LT with a similar iterative but linear method based on Rytov approximation.
Positron Annihilation Spectroscopy of Polystyrene Filled with Carbon Nanomaterials (2012)

Positron annihilation lifetime spectroscopy (PALS) was employed to study the free volume properties of polystyrene (PS) containing three different types of carbon nanoparticles: polystyrene-grafted single wall carbon nanotubes (SWCNTs-g-PS), single wall carbon nanotubes (SWCNTs), and carbon nanofibers (CNFs). The glass transition temperature measured via PALS was significantly lower than that from differential scanning calorimetry (DSC), although qualitatively the two methods agreed in that the Tg measured increased as nanotubes were added to the material. There were some specific differences between the two measurements which may have been related to the fact that DSC does not measure Tg of a portion of the material which is immobilized on the surface of the particle, while PALS measures all polymer, whether immobilized or not. PALS was also used to measure the thermal expansion coefficient and distributions of the free volume of the polystyrene.
Common Inorganic Salts Catalyze the Transformations of Organic Compounds in Atmospheric Aerosols (2008)

Common inorganic salts catalyze the transformations of organic compounds in atmospheric aerosols
Meta-surface-enabled ultra-sharp multimode waveguide bends on silicon (2018)

Mode-division-multiplexing (MDM) is attractive as a means to increase the link capacity of a single wavelength for optical interconnects via the use of multiple mode-channels in multimode bus waveguide.In order to route the data in MDM systems, waveguide bends are typically needed.In particular, ultra-sharp bends are desirable for reducing the chip area occupied by high-density photonic intergrated circuits (PICs). In this work, we propose and demonstrate a novel meta-surfaced waveguide structure on silicon, which enables ultral-sharp multimode waveguide bends to have low loss and low crosstalk among different mode-channels.An ultra-sharp S-bend with a bending radius of R=10μm is realized for an MDM optical interconnect with three mode-channels. The numerical simulation shows that the proposed ultal-sharp meta-surfaced multimode waveguide bend (MMWB) has low excess losses (0.2~0.5dB) and low inter-mode crosstalk (100nm) for all the three mode-channels. This is verified by experimental results, which show that the fabricated S-bends have excess losses of 0.5~0.8dB and inter-mode crosstalk of 60 nm. The experimental results were partially limited by the measurement setup, particularly the on-chip mode (de)multiplexers which had inter-mode crosstalk of about -20dB. The proposed MMWB can be extended for the transmission of more than three mode-channels.Our work paves the way to use meta-surfaced silicon photonic waveguide structures for on-chip multimode optical interconnect.
Hybrid C8-BTBT/InGaAs nanowire heterojunction for artificial photosynaptic transistors (2022)

Abstract The emergence of light-tunable synaptic transistors provides opportunities to break through the von Neumann bottleneck and enable neuromorphic computing. Herein, a multifunctional synaptic transistor is constructed by using 2,7-dioctyl[1]benzothieno[3,2-b][1]benzothiophene (C8-BTBT) and indium gallium arsenide (InGaAs) nanowires (NWs) hybrid heterojunction thin film as the active layer. Under illumination, the Type-I C8-BTBT/InGaAs NWs heterojunction would make the dissociated photogenerated excitons more difficult to recombine. The persistent photoconductivity caused by charge trapping can then be used to mimic photosynaptic behaviors, including excitatory postsynaptic current, long/short-term memory and Pavlovian learning. Furthermore, a high classification accuracy of 89.72% can be achieved through the single-layer-perceptron hardware-based neural network built from C8-BTBT/InGaAs NWs synaptic transistors. Thus, this work could provide new insights into the fabrication of high-performance optoelectronic synaptic devices.
Adapting Sequential Monte-Carlo Estimation to Cooperative Localization in Wireless Sensor Networks (2006)

Localization is a key function in Wireless Sensor Networks (WSNs). Many applications and internal mechanisms require nodes to know their location. This work proposes a new sequential estimation algorithm for distributed cooperative localization, whose simplicity makes it amenable to self-localization in Wireless Sensor Networks (WSNs), characterized by their restricted resources in energy and computation. The algorithm is inspired in sequential Monte-Carlo estimation techniques, viz. particle filters, that excel in robustness and simplicity for estimation applications. However, particle filters require significant amounts of memory and computational power for managing large numbers of particles. The presented technique reduces the number of particles, while retaining the convergence, accuracy and simplicity properties, as demonstrated in simulation experiments.
Supporting private information on public displays (2000)

The research area of Single Display Groupware (SDG) looks at how to best support multiple users collaborating around a single computer [4]. One outstanding issue in SDG research concerns how to display private information on shared displays. This paper discusses a mechanism by which private information can be selectively displayed to specific users that are gathered around a shared display. A prototype system is presented that implements the mechanism through the use of adapted stereographic hardware.
108: Increased Superoxide Formation with Simulated Low-Grade Systemic Inflammation: Implications for Erectile Dysfunction in Obesity and Pre-Diabetes (2006)

You have accessJournal of UrologyModerated Poster, Saturday, May 20, 2006, 3:30 - 5:30 pm1 Apr 2006108: Increased Superoxide Formation with Simulated Low-Grade Systemic Inflammation: Implications for Erectile Dysfunction in Obesity and Pre-Diabetes Christian H. Coyle, Ryuichi Kato, Michael B. Chancellor, William C. de Groat, Fernando De Miguel, and Naoki Yoshimura Christian H. CoyleChristian H. Coyle More articles by this author , Ryuichi KatoRyuichi Kato More articles by this author , Michael B. ChancellorMichael B. Chancellor More articles by this author , William C. de GroatWilliam C. de Groat More articles by this author , Fernando De MiguelFernando De Miguel More articles by this author , and Naoki YoshimuraNaoki Yoshimura More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)32375-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "108: Increased Superoxide Formation with Simulated Low-Grade Systemic Inflammation: Implications for Erectile Dysfunction in Obesity and Pre-Diabetes." The Journal of Urology, 175(4S), p. 35 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 35 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Christian H. Coyle More articles by this author Ryuichi Kato More articles by this author Michael B. Chancellor More articles by this author William C. de Groat More articles by this author Fernando De Miguel More articles by this author Naoki Yoshimura More articles by this author Expand All Advertisement PDF downloadLoading ...
Irresistible Materials multi-trigger resist: the journey towards high volume manufacturing readiness (2017)

Irresistible Materials (IM) is a UK company spun out of the University of Birmingham. It is developing novel resist systems based on the Multi-trigger concept, and spin-on-carbon hardmask materials. IM has developed a new EUV resist that is nonmetal based, does not need a post exposure bake (PEB), and delivers high sensitivity, excellent contact hole resolution, with low LER. It is being readied for HVM through a partnership with Nano-C, Inc. (the Massachusetts based manufacturer of advanced electronic materials and chemicals). The transition to scalability will be the highlight of this discussion.
ChemInform Abstract: Cold Molecular Beam Electronic Spectrum of C60 and C70. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
NAD Metabolism: Mechanisms of lifespan extension in yeast and nicotinamide riboside utilization in a healthy 50 year old man (2012)

More than 100 years after the discovery of the co‐enzyme requirement for glycolysis, more than 70 years after the discovery of niacins, more than 50 years after the discovery of the Preiss‐ Handler pathway of nicotinate utilization, and more than 10 years after the connections between NAD biosynthesis, calorie restriction and aging were discovered in yeast, we continue to find and attempt to fill major gaps in understanding of yeast and human NAD metabolism. In this paper, we will use LC‐MS and genetic analysis to dissect a surprising role for intercellular communication in yeast lifespan extension. We will also present a new chemical synthesis and a first‐in‐man clinical use of nicotinamide riboside, which reveals surprising differences in bioavailability from nicotinamide.
Magnesium regulates intracellular ionized calcium concentration and cell geometry in vascular smooth muscle cells (VSMC) (1991)

It has been suggested that the extracellular Mg{sup 2+} may modulate contractility of VSMC by controlling the cellular level of free Ca{sup 2+}. The present studies were designed to determine the effects of (Mg{sup 2+}) on the distribution of intracellular free Ca{sup 2+} using digital imaging fluorescence microscopy of Fura-2 fluorescence of single VSMC cultured from rat aortas. When incubated with HEPES buffer solution containing 1.2mM Mg{sup 2+}, the myocytes are spindle-shaped, and the basal level of (Ca{sup 2+}){sub i} estimated from the ratio (F340/F380) is 96.6 {plus minus} 7.9nM with a heterogeneous distribution. (Mg{sup 2+}){sub o} withdrawal from the incubation medium induces consistently a dramatic increment of (Ca{sup 2+}){sub i} up to 579.6 {plus minus} 39.3nM, about a 5.8-fold elevation compared to control experiments. Similarly, lowering (Mg{sup 2+}){sub o} to 0.3mM (the lowest physiological range) elevates (Ca{sup 2+}){sub i} to the intermediate level of 348.0 {plus minus} 31.5nM. However, the heterogeneous distribution of (Ca{sup 2+}){sub i} is still evident when (Mg{sup 2+}){sub o} is lowered. Simultaneously to the (Ca{sup 2+}){sub i} increments, cell shapes were changed. In contrast, elevation of (Mg{sup 2+}){sub o} to 4.8mM was found to decrease (Ca{sup 2+}){sub i} to 72.0 {plus minus} 4.6nM. Removal ofmore » (Ca{sup 2+}){sub o}, however, abolished the increments of (Ca{sup 2+}){sub i} induced by (Mg{sup 2+}){sub o} withdrawal. These results demonstrate that (Mg{sup 2+}){sub o} regulated (Ca{sup 2+}){sub i} and geometry of VSMC, probably through controlling plasma membrane permeability to Ca{sup 2+}.« less
Pilot Pharmacokinetic and Dosimetric Studies of18F-FPPRGD2: A PET Radiopharmaceutical Agent for Imaging αvβ3Integrin Levels (2011)

(18)F-FPPRGD2 has desirable pharmacokinetic and biodistribution properties. The primary application is likely to be PET evaluation of oncologic patients-especially those with brain, breast, or lung cancer. Specific indications may include tumor staging, identifying patients who would benefit from antiangiogenesis therapy, and separating treatment responders from nonresponders early.
Unlock Your Heart: Next Generation Biometric in Resource-Constrained Healthcare Systems and IoT (2019)

With the emergence of the Internet-of-Things, there is a growing need for access control and data protection on low-power, pervasive devices. Key-based biometric cryptosystems are promising for IoT due to its convenient nature and lower susceptibility to attacks. However, the costs associated with biometric processing and template protection are nontrivial for smart cards, and so forth. In this paper, we discuss the cost versus the utility of biometric systems and investigate frameworks for improving them. We propose the noise-aware biometric quantization framework (NA-IOMBA) capable of generating unique, reliable, and high entropy keys with low enrollment times and costs with several experiments. First, we compare its performance with IOMBA and one-class-SVM on multiple biometric modalities, including popular ones (fingerprint and iris) and emerging cardiovascular ones (ECG and PPG). The results show that NA-IOMBA outperforms them all and that ECG provides the best trade-off between reliability, key length, entropy, and implementation cost. Second, we examine the impact on key reliability with ECGs obtained at different sessions and trained with a different number of heartbeats. Finally, implementation results show that incorporating noise models with NA-IOMBA reduces power and utilization overhead by more than 60% by adapting the pre-processing, feature extraction, and post-processing modules.
The Kondrat’eva Reaction in Flow: Direct Access to Annulated Pyridines (2013)

A continuous flow inverse-electron-demand Kondrat'eva reaction has been developed that provides direct access to cycloalka[c]pyridines from unactivated oxazoles and cycloalkenes. Annulated pyridines obtained by this one-step process are valuable scaffolds for medicinal chemistry.