gebhart/patrepeval huggingface dataset:
Made by Robots : Challenging Architecture at A Larger Scale (2014)

Meskipun sangat ambisius dan canggih, sebagian besar upaya menggunakan proses robotik dalam arsitektur tetap menjadi pengecualian; sedikit lebih dari prototipe atau bahkan kegagalan pada skala yang lebih besar. Ini karena pendekatan umumnya adalah mengotomatiskan proses manual yang ada atau proses konstruksi lengkap. Namun, potensi nyata robot tetap tidak tereksploitasi jika digunakan hanya untuk pelaksanaan proses fabrikasi massal yang sangat berulang: kemampuan mereka untuk produksi serial elemen non-standar serta untuk berbagai proses konstruksi sebagian besar terbuang percuma. Untuk meningkatkan dan memajukan aplikasi robotika, baik untuk prefabrikasi dan konstruksi di tempat, perlu ada pemahaman tentang kemampuan yang berbeda, dan ini harus dipertimbangkan sejak awal proses desain dan perencanaan. Edisi AD ini menampilkan temuan modul penelitian Arsitektur dan Fabrikasi Digital di ETH Zurich Future Cities Laboratory di Singapura, disutradarai oleh Fabio Gramazio dan Matthias Kohler, yang mengeksplorasi kemungkinan proses konstruksi robotik untuk arsitektur dan aplikasi berskala besar untuk desain dan konstruksi gedung bertingkat tinggi. Bersama dengan kontributor lainnya, mereka juga melihat transformasi luas yang mulai terjadi dalam fabrikasi otomatis: dalam hal pembebasan tenaga kerja, kewirausahaan, perubahan bentuk lokasi bangunan, fabrikasi in-situ dan, yang paling penting, desain.

Kontributor: Thomas Bock, Jelle Feringa, Philippe Morel, Neri Oxman, Antoine Picon dan Francois Roche.

Kontributor ETH Zurich: Michael Budig, Norman Hack, Willi Lauer dan Jason Lim dan Raffael Petrovic (Laboratorium Kota Masa Depan), Volker Helm, Silke Langenberg dan Jan Willmann.

Pengusaha unggulan: Greyshed, Machineous, Odico Formwork Robotics, RoboFold dan ROB Technologies.
Epitaxial ZnO Thin Films ona-Plane Sapphire Substrates Grown by Ultrasonic Spray-Assisted Mist Chemical Vapor Deposition (2009)

High-quality epitaxial ZnO thin films were grown by an ultrasonic spray-assisted mist chemical vapor deposition (CVD) on a-plane sapphire substrates with ZnO buffer layers. The ZnO thin films were grown with c-axis orientation without notable rotational domains. Surface morphologies and electrical properties were markedly improved as an effect of the ZnO buffer layers. The mobility in the ZnO epitaxial (main) layer was estimated to be 90 cm2/(V·s), which is reasonably high compared with those in ZnO layers grown by CVD processes. Photoluminescence at a low temperature (4.5 K) revealed a free A-exiton peak, and that at room temperature showed a strong band-edge peak with little deep-level luminescence.
ChemInform Abstract: ORGANOPHOSPHORVERBINDUNGEN, (VERMUTLICH) 142. MITT. RK. VON DIALKYLPHOSPHITEN MIT PHOSPHORSAEUREDIALKYLESTERCHLORIDEN IN GEGENWART TERTIAERER AMINE (1970)

Abstract Phosphit (1) und Chlorid (II) bilden in Gegenwart von Triäthylamin in Benzol das Pyrophosphit (V) (5,7% Ausbeute), das Anhydrid (IV) (8%) und das Pyrophosphat (III) (40,5%) dessen Bildungsmechanismus untersucht wird.
A GC–MS and LC–HRMS perspective on the chemotaxonomic investigation of the natural hybrid Origanum × lirium and its parents, O. vulgare subsp. hirtum and O. scabrum (2023)

Altogether, the present work provides useful information on the chemical composition of the taxa under investigation, while our findings support the opinion that Origanum × lirium should be considered not as a separate species, but rather as a hybrid on the way to becoming a species.
Visualization of multimodality cardiac imagery (1990)

A large number of clinically important and medically difficult decisions in diagnostic radiology involve interpreting the information derived from multiple imaging modalities. This is especially true in the assessment of heart disease, wherein at least two types of image information are generally required prior to deciding on the course of action: structural information describing coronary vessel anatomy and functional information related to heart muscle physiology. This paper will present and discuss the methods and results associated with a research program aimed at quantifying and visualizing the unified anatomic and physiologic information obtained from these complementary imaging modalities. The discussions will emphasize the reconstruction, processing, and visualization of three-dimensional cardiovascular structure, including the procedures and results obtained from phantom and patient studies.
Simulation of two-photon absorption in Raman DFB lasers (2012)

We present an efficient split-step solver for the nonlinear coupled mode equations with two-photon absorption to investigate the feasibility of Raman DFB lasers in highly nonlinear materials such as chalcogenide glasses.
Hedgehog Signaling: Progenitor Phenotype in Small-Cell Lung Cancer (2003)

Recently, we have shown that small cell lung cancer (SCLC) is dependent on activation of Hedgehog signaling, an embryonic pathway implicated in development, morphogenesis and the regulation of stem cell fates. These findings form the framework for an emerging view of cancer as a process of aberrant organogenesis in which progenitor/ stem cells escape dependence on niche signaling through mutation in genes such as Ptch, or through persistent activation of progenitor cell pathways. Interestingly, the normally quiescent airway epithelial compartment uses the Hh pathway to repopulate itself when challenged by injury. How Hh signaling works to promote the malignant phenotype promises to be as important biologically as the promise of Hh pathway inhibitors are clinically.
Difficulty of carrier generation in orthorhombic PbO (2016)

Polycrystalline β-PbO films were grown by pulsed laser deposition in atmospheres ranging from oxygen-poor (the oxygen pressure of 0.01 Pa) to oxygen-rich (13 Pa) conditions, and the oxygen chemical potential was further enhanced by ozone annealing to examine hole doping. It was found that each of the as-grown β-PbO films showed poor electrical conductivity, σ &amp;lt; 1.4 × 10−7 S cm−1, regardless of the oxygen pressure. The density functional calculations revealed that native defects including Pb and O vacancies have deep transition levels and extremely high formation enthalpies, which indicates difficulty of carrier generation in β-PbO and explains the experimentally observed poor electrical conductivity. The analysis of the electronic structures showed that the interaction between Pb 6s and O 2p orbitals is weak due to the deep energy level of Pb 6s and does not raise the valence band maximum (VBM) level unlike that observed in SnO, which is also supported by ultraviolet photoemission spectroscopy measurements. The deep acceptor transition levels of the native defects are attributed to the deep VBM of β-PbO. On the other hand, annealing β-PbO films in reactive oxygen-containing atmospheres (i.e., O3) led to a significantly enhanced electrical conductivity (i.e., σ &amp;gt; 7.1 × 102 S cm−1) but it is the result of the formation of an n-type PbO2 phase because oxygen chemical potential exceeded the phase boundary limit. The striking difference in carrier generation between PbO and SnO is discussed based on the electronic structures calculated by density functional theory.
Toward a clinical antifungal peptoid: Investigations into the therapeutic potential of AEC5 (2019)

Cryptococcus neoformans is a fungal pathogen that causes cryptococcal meningitis in immunocompromised individuals. Existing antifungal treatment plans have high mammalian toxicity and increasing drug resistance, demonstrating the dire need for new, nontoxic therapeutics. Antimicrobial peptoids are one alternative to combat this issue. Our lab has recently identified a tripeptoid, AEC5, with promising efficacy and selectivity against C. neoformans. Here, we report studies into the broad-spectrum efficacy, killing kinetics, mechanism of action, in vivo half-life, and subchronic toxicity of this compound. Most notably, these studies have demonstrated that AEC5 rapidly reduces fungal burden, killing all viable fungi within 3 hours. Additionally, AEC5 has an in vivo half-life of 20+ hours and no observable in vivo toxicity following 28 days of daily injections. This research represents an important step in the characterization of AEC5 as a practical treatment option against C. neoformans infections.
Data from Cholesterol Depletion by TASIN-1 Induces Apoptotic Cell Death through the ER Stress/ROS/JNK Signaling in Colon Cancer Cells (2023)

&lt;div&gt;Abstract&lt;p&gt;Truncated APC selective inhibitor-1 (TASIN-1) is a recently identified small molecule that selectively kills colorectal cancer cells that express truncated adenomatous polyposis coli (APC) by reducing cellular cholesterol levels. However, the downstream mechanism responsible for its cytotoxicity is not well understood. In this study, we show that TASIN-1 leads to apoptotic cell death via inducing ER stress-dependent JNK activation in human truncated APC colon cancer cells, accompanied by production of reactive oxygen species (ROS). In addition, TASIN-1 inhibits AKT activity through a cholesterol-dependent manner. Human colon tumor xenografts in immunodeficient mice also show the same TASIN-1 induced molecular mechanisms of tumor cell death as observed &lt;i&gt;in vitro&lt;/i&gt;. Taken together, cholesterol depletion by TASIN-1 treatment induces apoptotic cell death through activating ER stress/ROS/JNK axis and inhibiting AKT pro-survival signaling in colon cancer cells with truncated APC both &lt;i&gt;in vitro&lt;/i&gt; and &lt;i&gt;in vivo&lt;/i&gt;. &lt;i&gt;Mol Cancer Ther; 17(5); 943–51. ©2018 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
Demo (2016)

We present ForcePhone, a novel system of enabling commodity phones to recognize the force applied to their touch screen and body. Researchers have shown the usefulness and importance of this expressive input interface (especially for the one-hand operation), but this advanced function has not yet been realized and deployed in most state-of-the-art smartphones. Instead of augmenting specialized/proprietary sensors, ForcePhone uses only the phone's built-in sensors to measure the applied force via a physical property called structure-borne sound propagation. ForcePhone has been implemented and evaluated on both iOS and Android phones. Multiple demo applications based on ForcePhone have been implemented and tested. The estimated force is shown highly correlated to the real applied force and the estimation error is low enough to support various applications. Most participants in our usability study were able to master the ForcePhone-based apps and find them very useful.
Graph-Regularized Fast Low-Rank Matrix Approximation Using The NystrÖM Method for Clustering (2018)

In recovering low-dimensional representations of high-dimensional data, graph or manifold-regularized schemes have been investigated as a key tool in many areas to preserve the neighborhood structure of the data set. In spite of its effectiveness, these methods are often not tractable in practice, because graph structures of data lead to a large matrix (e.g., affinity of Laplacian matrix) and the methods require eigenanalysis of it interactively. In this paper, we propose an efficient low-rank matrix approximation that regularized by graph information derived from row and column range spaces of data. To deal with high computational complexity issue, we leverage the Nyström method, which has been universally used to approximate low-rank component of Symmetric Positive Semi-Definite (SPSD) matrices with sampling. Moreover, we devise a Clustered Nystrom extension with QR decomposition to efficiently aggregate more information from samples and to accurately approximate low-rank structure. We compare the performance of the proposed algorithm with other several general algorithms in clustering experiments on benchmark dataset. Our experimental results show that our method has a favorable running speed while the accuracy of our proposed method is better or comparable to the competing methods.
Enhancing the control and efficiency of the covering process [logic verification] (2004)

Coverage directed test generation (CDG) is a technique for providing feedback from the coverage domain back to a generator that produces new stimuli to the tested design. In this paper, we describe two algorithms that act in a CDG framework. The first algorithm controls the coverage events distribution using a "water-filling" approach. The second algorithm improves the efficiency of the covering process using clustering techniques.
Impaired NLRP3 inflammasome activation/pyroptosis leads to robust inflammatory cell death via caspase-8/RIPK3 during coronavirus infection (2020)

Coronaviruses have caused several zoonotic infections in the past two decades, leading to significant morbidity and mortality globally. Balanced regulation of cell death and inflammatory immune responses is essential to promote protection against coronavirus infection; however, the underlying mechanisms that control these processes remain to be resolved. Here we demonstrate that infection with the murine coronavirus mouse hepatitis virus (MHV) activated the NLRP3 inflammasome and inflammatory cell death in the form of PANoptosis. Deleting NLRP3 inflammasome components or the downstream cell death executioner gasdermin D (GSDMD) led to an initial reduction in cell death followed by a robust increase in the incidence of caspase-8- and receptor-interacting serine/threonine-protein kinase 3 (RIPK3)-mediated inflammatory cell deathafter coronavirus infection. Additionally, loss of GSDMD promoted robust NLRP3 inflammasome activation. Moreover, the amounts of some cytokines released during coronavirus infection were significantly altered in the absence of GSDMD. Altogether, our findings show that inflammatory cell death, PANoptosis, is induced by coronavirus infection and that impaired NLRP3 inflammasome function or pyroptosis can lead to negative consequences for the host. These findings may have important implications for studies of coronavirus-induced disease.
Extrinsic optical-fiber ultrasound sensor using a thin polymer film as a low-finesse Fabry–Perot interferometer (1996)

Theoretical and experimental aspects of an extrinsic optical-fiber ultrasound sensor are described. The sensor is based on a thin transparent polymer film acting as a low-finesse Fabry-Perot cavity that is mounted at the end of a multimode optical fiber. Performance was found to be comparable with that of a piezoelectric polyvinylidene dinuoride-membrane (PVDP) hydrophone with a sensitivity of 61 mV/MPa, an acoustic noise floor of 2.3 KPa over a 25-MHz bandwidth, and a frequency response to 25 MHz. The wideband-sensitive response and design flexibility of the concept suggests that it may find application as an alternative to piezoelectric devices for the detection and measurement of ultrasound.
Synthesis and Electron−Phonon Interactions of Ce3+-Doped YAG Nanoparticles (2009)

Nanoparticles of cerium-doped yttrium aluminum garnet (YAG:Ce3+) phosphors were synthesized by a nonhydrolytic solvothermal method yielding particle sizes less than 10 nm. Oleic acid and oleylamine effectively capped the nanoparticles during the synthesis and allowed crystallization of garnet to take place at 300 °C. This facile approach will find wide acceptance and could be used in synthesizing other complex oxide nanoparticles. Studies on electron−phonon interactions in the nanoparticles have been carried out by fitting the observed optical spectra with the multimode Brownian oscillator model. Compared to the same material of larger particle sizes (30 nm, 250 nm, and bulk), the electron−phonon coupling strength is found to be much weaker.
Fabrication of conducting AFM cantilevers with AlN-based piezoelectric actuators (2011)

This paper presents a new fabrication technology for conducting AFM cantilevers with integrated AlN-based piezoelectric actuators. A major effort has been done for the process integration of a high quality AlN layer onto the Si cantilever together with a high wear resistance, PtSi-based conducting tip. Functional AFM devices have been successfully tested in tapping mode imaging experiments. Such type of cantilevers are of great interest for dynamic AFM applications especially for tapping or dithering mode AFMs as well as for using the piezoelectric structures as an integrated position sensor.
proteins in direct competition with an Ets activator (2001)

Ikaros is a unique regulator of lymphopoiesis that associates with pericentromeric heterochromatin and has been implicated in heritable gene inactivation. Binding and competition experiments demonstrate that Ikaros dimers compete with an Ets activator for occupancy of the lymphocyte-specific TdT promoter. Mutations that selectively disrupt Ikaros binding to an integrated TdT promoter had no effect on promoter function in a CD4 + CD8 + thymocyte line. However, these mutations abolished down-regulation on differentiation, providing evidence that Ikaros plays a direct role in repression. Reduced access to restriction enzyme cleavage suggested that chromatin alterations accompany down-regulation. The Ikaros-dependent down-regulation event and the observed chromatin alterations appear to precede pericentromeric repositioning. Current models propose that the functions of Ikaros should be disrupted by a small isoform that retains the dimerization domain and lacks the DNA-binding domain. Surprisingly, in the CD4 + CD8 + thymocyte line, overexpression of a small Ikaros isoform had no effect on differentiation or on the pericentromeric targeting and DNA-binding properties of Ikaros. Rather, the small isoform assembled into multimeric complexes with DNA-bound Ikaros at the pericentromeric foci. The capacity for in vivo multimer formation suggests that interactions between Ikaros dimers bound to the TdT promoter and those bound to pericentromeric repeat sequences may contribute to the pericentromeric repositioning of the inactive gene.
A Very High Speed and Efficient CIC Decimation Filter Core (2006)

A very high speed CIC decimation filter core is proposed in this paper. Based on partial-polyphase decomposition techniques, the core can operate at much lower sampling rate while achieving the same performances as Hogenauer’s CIC filter. It can receive data sampled at frequency 2, 4, or 8 times higher than that of the most commercially available cores without multiplying by 2, 4, or 8 the resources needed for an FPGA implementation. It is completely parameterizable and flexible at design time. The core has advantages in high speed operation like direct RF sampling.
Machine Learning Estimation of Plateau Stress of Aluminum Foam Using X-ray Computed Tomography Images (2023)

Owing to its lightweight and excellent shock-absorbing properties, aluminum foam is used in automotive parts and construction materials. If a nondestructive quality assurance method can be established, the application of aluminum foam will be further expanded. In this study, we attempted to estimate the plateau stress of aluminum foam via machine learning (deep learning) using X-ray computed tomography (CT) images of aluminum foam. The plateau stresses estimated by machine learning and those actually obtained using the compression test were almost identical. Consequently, it was shown that plateau stress can be estimated by training using the two-dimensional cross-sectional images obtained nondestructively via X-ray CT imaging.
Black indium oxide a photothermal CO2 hydrogenation catalyst (2020)

Nanostructured forms of stoichiometric In<sub>2</sub>O<sub>3</sub> are proving to be efficacious catalysts for the gas-phase hydrogenation of CO<sub>2</sub>. These conversions can be facilitated using either heat or light; however, until now, the limited optical absorption intensity evidenced by the pale-yellow color of In<sub>2</sub>O<sub>3</sub> has prevented the use of both together. To take advantage of the heat and light content of solar energy, it would be advantageous to make indium oxide black. Herein, we present a synthetic route to tune the color of In<sub>2</sub>O<sub>3</sub> to pitch black by controlling its degree of non-stoichiometry. Black indium oxide comprises amorphous non-stoichiometric domains of In<sub>2</sub>O<sub>3-x</sub> on a core of crystalline stoichiometric In<sub>2</sub>O<sub>3</sub>, and has 100% selectivity towards the hydrogenation of CO<sub>2</sub> to CO with a turnover frequency of 2.44 s<sup>-1</sup>.
Stereocomplexes of A−B−A Triblock Copolymers Based on Poly(l-Lactide) and Poly(d-Lactide) A Blocks (2005)

A series of A−B−A triblock copolymers was prepared by a Sn(II) 2-ethylhexanoate catalyzed chain extension of various telechelic soft segments, with l,l-lactide (LLA). Poly(ε-caprolactone)s, PεCL, poly(ethylene glycol)s, PEG, and a poly(dimethyl siloxane), PDMS, served as soft segments. The lengths of both soft and hard segments (poly-LLA, PLLA, or poly-d,d-lactide, PDLA) were varied. For the lactide blocks, average lengths of 25, 50, and 100 lactic acid units were selected. An analogous series of A−B−A triblock copolymers was prepared with DLA. Compositions and block lengths of these triblock copolymers were characterized by 1H NMR spectroscopy. Furthermore, stereocomplexes (racemates) of PLLA- and PDLA-based triblock copolymers were prepared to find out if the attractive forces between PLLA and PDLA blocks or the repulsive forces between incompatible soft segments dominate the morphology. Both neat triblock copolymers and stereocomplexes were characterized by differential scanning calorimtery measurements by wide-angle X-ray diffraction. The influence of block lengths on glass transition (Tg) and melting temperatures (Tm) of soft and hard segments was studied in detail. Stereocomplexes of all triblock combinations were obtained, even when the soft segments were incompatible.
Commingled Plastic Guardrail Post (1995)

There has been an increased interest in the use of recyclable materials due to environmental and economic concerns. As a result, the use of recycled materials in roadside safety features is being explored. In the present paper, a guardrail post manufactured from recycled plastic and steel is evaluated for possible use along highways. Tests were carried out on two cross-sectional configurations. A static cantilever bending test shows that although the plastic posts have less stiffness and strength than a standard wooden post, their energy absorption is approximately three times as large as their wooden counterpart. The plastic posts behaved essentially as rigid elements and sustained no permanent damage in standard in-situ tests. A large pendulum was used to impact the posts in an in-situ condition, and also with a fixed base and a variation of post temperature. Comparison of performance with standard posts was favorable. Finally, a full-scale crash test using a 20-kN (4,500-lb) automobile traveling at 96 km/h (mi/h) and making contact at a 25° angle shows that the commingled plastic post and W-beam guardrail can successfully contain and redirect an errant vehicle.