gebhart/patrepeval huggingface dataset:
720: Characteristics of Enhancing Renal Masses with Zero Net Growth During Active Surveillance (2006)

You have accessJournal of UrologyDiscussed Poster, Monday, May 22, 2006, 1:00 - 4:00 pm1 Apr 2006720: Characteristics of Enhancing Renal Masses with Zero Net Growth During Active Surveillance David A. Kunkle, Paul L. Crispen, David Y.T. Chen, Richard E. Greenberg, and Robert G. Uzzo David A. KunkleDavid A. Kunkle More articles by this author , Paul L. CrispenPaul L. Crispen More articles by this author , David Y.T. ChenDavid Y.T. Chen More articles by this author , Richard E. GreenbergRichard E. Greenberg More articles by this author , and Robert G. UzzoRobert G. Uzzo More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)32956-2AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "720: Characteristics of Enhancing Renal Masses with Zero Net Growth During Active Surveillance." The Journal of Urology, 175(4S), p. 233 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 233 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information David A. Kunkle More articles by this author Paul L. Crispen More articles by this author David Y.T. Chen More articles by this author Richard E. Greenberg More articles by this author Robert G. Uzzo More articles by this author Expand All Advertisement PDF downloadLoading ...
Histone carbonylation in vivo and in vitro (2000)

Non-enzymic damage to nuclear proteins has potentially severe consequences for the maintenance of genomic integrity. Introduction of carbonyl groups into histones in vivo and in vitro was assessed by Western blot immunoassay and reductive incorporation of tritium from radiolabelled NaBH4 (sodium borohydride). Histone H1 extracted from bovine thymus, liver and spleen was found to contain significantly elevated amounts of protein-bound carbonyl groups as compared with core histones. The carbonyl content of nuclear proteins of rat pheochromocytoma cells (PC12 cells) was not greatly increased following oxidative stress induced by H2O2, but was significantly increased following alkylating stress induced by N-methyl-N´-nitro-N-nitrosoguanidine or by combined oxidative and alkylating stress. Free ADP-ribose, a reducing sugar generated in the nucleus in proportion to DNA strand breaks, was shown to be a potent histone H1 carbonylating agent in isolated PC12 cell nuclei. Studies of the mechanism of histone H1 modification by ADP-ribose indicate that carbonylation involves formation of a stable acyclic ketoamine. Our results demonstrate preferential histone H1 carbonylation in vivo, with potentially important consequences for chromatin structure and function.
A Comprehensive Obstetrics Patient Safety Program Improves Safety Climate and Culture (2012)

Log in or Register Subscribe to journalSubscribe Get new issue alertsGet alerts Enter your Email address: Wolters Kluwer Health may email you for journal alerts and information, but is committed to maintaining your privacy and will not share your personal information without your express consent. For more information, please refer to our Privacy Policy. Subscribe to eTOC Secondary Logo Journal Logo All Articles Images Videos Podcasts Blogs Advanced Search Toggle navigation Subscribe Register Login Articles & Issues Current IssuePrevious Issues Collections Obstetric Airway ManagementMaternal EmbolismRegional Anesthesia for Cesarean SectionGeneral Anesthesia for Cesarean SectionAnalgesia for LaborObstetric HemorrhagePre-Eclampsia/EclampsiaPharmacologyTraumaInfection and SepsisMaternal ObesityMaternl Morbidity and MortalityNeonatal Morbidity and MortalityObstetric ComplicationsAnesthetic ComplicationsNon-Obstetric Maternal DiseaseCritical CareDrug Abuse in PregnancyEthicsSystems Based Practice For Authors Information for AuthorsLanguage Editing Services Journal Info About the JournalEditorial BoardAdvertisingOpen AccessSubscription ServicesReprintsRights and Permissions All Articles Images Videos Podcasts Blogs Advanced Search
2,5‐Disubstituted Pyrazolo[4,3‐c]cinnolin‐3‐ones (2016)

Complementary strategies to 2,5‐disubstituted pyrazolo[4,3‐ c ]cinnolin‐3‐ones are reported herein, providing late stage substituent introduction at either the 2‐ or the 5‐position. Treating a readily prepared 4‐thiocinnoline ester with substituted hydrazines afforded late stage access to the 2‐position, while late stage substituent introduction at the 5‐position was achieved via two different strategies: alkylation of 4‐hydrazonopyrazol‐3‐ones, followed by a ring‐closing intramolecular S N Ar tactic and direct reaction of 5‐(2‐fluorophenyl)‐2,4‐dihydro‐3 H ‐pyrazol‐3‐ones with aryl diazonium salts, followed by cyclization. The strategies described herein provide practical and general methods to prepare 2,5‐disubstituted pyrazolo[4,3‐ c ]cinnolin‐3‐ones.
Clinical-radiological evaluation of sequelae of stereotactic radiosurgery for intracranial arteriovenous malformations (1989)

Stereotactic heavy-charged-particle Bragg peak radiosurgery has been used to treat 322 patients with surgically-inaccessible intracranial vascular malformations. (The clinical results of this method for the treatment of angiographically demonstrable arteriovenous malformations (AVMs) and angiographically occult vascular malformations (AOVMs) of the brain are described in separate reports of this symposium). The great majority of patients have had an uneventful post-treatment course with satisfactory health outcomes. However, several categories of delayed sequelae of stereotactic radiosurgery have been identified, involving the vascular structures essential for the integrity of the brain tissue and the brain parenchyma directly. These categories reflect both reaction to injury and to alterations in regional hemodynamic status, and include vasogenic edema, occlusion of functional vasculature, radiation necrosis, and local or remote effects on cerebral arterial aneurysms. 10 refs., 7 figs., 1 tab.
Supplementary Figure 2 from TLR2 Agonist PSK Activates Human NK Cells and Enhances the Antitumor Effect of HER2-Targeted Monoclonal Antibody Therapy (2023)

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Trends in readmission rate by route of hysterectomy – a single‐center experience (2017)

Abstract Introduction The aim of this study was to assess the 60‐day readmission rates after hysterectomy according to route of surgery and analyze risk factors for postoperative readmission. Material and methods This retrospective study included all women who underwent hysterectomy due to benign conditions from 2009 to 2015 at a large academic center in Boston. Readmission rates were compared among the following four types of hysterectomies: abdominal, laparoscopic, robotic and vaginal. Results There were 3981 hysterectomy cases over the study period (628 abdominal hysterectomy, 2500 laparoscopic hysterectomy, 155 robotic hysterectomy and 698 vaginal hysterectomy). Intraoperative complications occurred more frequently in women undergoing abdominal hysterectomy (4.8%), followed by robotic hysterectomy (3.9%), vaginal hysterectomy (1.9%) and laparoscopic hysterectomy (1.6%) ( p &lt; 0.0001). Readmission rates were not significantly different among the groups; women receiving abdominal hysterectomy had an overall readmission rate of 3.5%, compared with 3.2% after robotic hysterectomy, 2.9% after vaginal hysterectomy and 1.9% after laparoscopic hysterectomy ( p = 0.06). When stratifying for relevant variables, women who had an laparoscopic hysterectomy had a twofold reduction of readmission compared with abdominal hysterectomy (odds ratio 0.52, 95% confidence interval 0.31–0.87; p = 0.01). There was no significant difference in readmission when robotic hysterectomy or vaginal hysterectomy were compared individually with abdominal hysterectomy. Regarding risk factors related to readmission it was observed that perioperative complications were the largest driver of readmissions (odds ratio 667, 95% confidence interval 158–99; p &lt; 0.0001). Conclusion The laparoscopic approach to hysterectomy was associated with fewer hospital readmissions compared with the abdominal route; vaginal, robotic and abdominal approaches had a similar risk of readmission. Perioperative complications represent the main driver of readmissions. After adjusting for perioperative factors such as surgeon type and complications, no difference in readmissions between the different routes of hysterectomy were found.
Controlling the emission of quantum dots embedded in photonic crystal nanocavity by manipulating Q-factor and detuning (2011)

We investigated the modulation of the Purcell effect by controlling the $Q$-factor and detuning in a quantum-dot--nanocavity coupled system. The $Q$-factor and detuning are controlled independently using a nanocavity and a waveguide reflector formed in a two-dimensional photonic crystal (PC) slab, in combination with a newly developed nitrogen adsorption/desorption method that enables local control of the refractive index. For example, we observed that the emission of a quantum dot via a cavity mode was increased by 3.3 times when the $Q$-factor was changed from 3500 to 6900 while keeping the detuning fixed. The dependence of the Purcell effect on the $Q$-factor has thus been directly observed.
An Experimental Analysis of Unanimity in Public Goods Provision Mechanisms (1988)

The paper reports on an experimental investigation of four methods of allocating public goods. The two basic processes studied are direct contribution and a public goods auction process. Both of these processes are studied with and without an additional unanimity feature. The results suggest that the auction process outperforms direct contribution. The effect of unanimity is to decrease the efficiency of both processes. Much of the paper is focused on an analysis of these results.
Nanowire to Single-Electron Transistor Transition in Trigate SOI MOSFETs (2010)

We investigate the effect of symmetrical geometrical constrictions on the electrical characteristics of ultrathin silicon-on-insulator nanowires with a trigate structure using a 3-D numerical quantum simulator. Introducing barriers at the source and drain junctions profoundly alter the device physics and a transition from 1-D to 0-D quantum behavior is observed. The constrictions create resonance levels in the channel region of nanowire due to confinement in the three directions of space, which, in turn, causes oscillation of the I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">D</sub> -V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">GS</sub> characteristic. Based on the observed characteristics, we derive a set of parameters that draws the line between 1-D and 0-D quantum behavior of silicon nanowire transistors.
Aromatic Polyester-Polysiloxane Block Copolymers: Multiphase Transparent Damping Materials. (1986)

Abstract : This research describes the synthesis and characterization of multiphase, transparent block copolymers that are potential candidates for passive damping applications in large space structures. Relatively high molecular weight polysiloxane-polyarylester block copolymers were prepared by two different synthetic routes. A solution technique was used to synthesize well-defined, perfectly alternating block copolymers by reacting a disfunctional hydroxyl-terminated polyarylester obligomer. A second approach involved the preparation of a segmented (or random) block copolymer by an interfacial, phase-transfer technique in which various polyarylester block lengths are formed during the copolymerization by reacting bisphenol-A, terephthaloyl chloride, and isophthaloyl chloride with a disfunctiinal aminopropyl-terminated siloxane block compositions (Dimethyl,
Online Task Allocation and Flying Control in Fog-Aided Internet of Drones (2020)

Fog-aided Internet of Drones (IoD) networks employ fog nodes to provide computing resources for the delay-sensitive tasks offloaded from drones. In IoD networks, drones are launched to complete a journey in which several locations of interest are visited. At each location, a drone collects the ground information, generates computing tasks and offloads them to the fog nodes for processing. In our work, we consider both the task allocation (which distributes tasks to different fog nodes) and the flying control (which adjusts the drone's flying speed) to minimize the drone`s journey completion time constrained by the drone's battery capacity and task completion deadlines. We formulate this joint optimization problem as a mixed integer non-linear programming (MINLP) problem. In consideration of the practical scenario that the future task information is difficult to obtain, we design an online algorithm to provide strategies for task allocation and flying control when the drone visits each location without knowing the future. The performances of our proposed online algorithm are demonstrated via extensive simulations.
Receptor Complementation and Mutagenesis Reveal SR-BI as an Essential HCV Entry Factor and Functionally Imply Its Intra- and Extra-Cellular Domains (2009)

HCV entry into cells is a multi-step and slow process. It is believed that the initial capture of HCV particles by glycosaminoglycans and/or lipoprotein receptors is followed by coordinated interactions with the scavenger receptor class B type I (SR-BI), a major receptor of high-density lipoprotein (HDL), the CD81 tetraspanin, and the tight junction protein Claudin-1, ultimately leading to uptake and cellular penetration of HCV via low-pH endosomes. Several reports have indicated that HDL promotes HCV entry through interaction with SR-BI. This pathway remains largely elusive, although it was shown that HDL neither associates with HCV particles nor modulates HCV binding to SR-BI. In contrast to CD81 and Claudin-1, the importance of SR-BI has only been addressed indirectly because of lack of cells in which functional complementation assays with mutant receptors could be performed. Here we identified for the first time two cell types that supported HCVpp and HCVcc entry upon ectopic SR-BI expression. Remarkably, the undetectable expression of SR-BI in rat hepatoma cells allowed unambiguous investigation of human SR-BI functions during HCV entry. By expressing different SR-BI mutants in either cell line, our results revealed features of SR-BI intracellular domains that influence HCV infectivity without affecting receptor binding and stimulation of HCV entry induced by HDL/SR-BI interaction. Conversely, we identified positions of SR-BI ectodomain that, by altering HCV binding, inhibit entry. Finally, we characterized alternative ectodomain determinants that, by reducing SR-BI cholesterol uptake and efflux functions, abolish HDL-mediated infection-enhancement. Altogether, we demonstrate that SR-BI is an essential HCV entry factor. Moreover, our results highlight specific SR-BI determinants required during HCV entry and physiological lipid transfer functions hijacked by HCV to favor infection.
Optical limiting studies in a carbon-black suspension for subnanosecond and subpicosecond laser pulses (2002)

This paper presents results of measurements of short (0.3 ps, 0.2 ns, and 10 ns) laser pulse transmissions through a liquid suspension of fine carbon particles (named CBS for "carbon-black suspension") at input-pulse energies up to 10 mJ. The 10-ns pulses came from a Nd:YAG laser at 1064 nm, and the shorter pulses came from a Ti:sapphire laser at 800 nm. Limiting was observed with the 10-ns and the 0.2-ns laser pulses, but the 0.3-ps pulses produced white light and underwent the same level of attenuation in the solvent and in the CBS.
Recent trends in the structural revision of natural products (2018)

Covering: 2012 to 2017 This article reviews recent reports on the structural revision of natural products. Through a critical assessment of the original and revised published structures, the article addresses why each structure was targeted for revision, discusses the techniques and key discrepancies that led to the proposal of the revised structure, and offers measures that may have been taken during the original structure determination to prevent error. With the revised structures in hand, weaknesses of original proposals are assessed, providing a better understanding on the logic behind structure determination.
Neural networks and handwritten signature verification (1991)

In this thesis, various neural networks are trained to detect true signatures of several subjects, and reject forgeries of these same signatures. The forgeries presented to the network are unpracticed forgeries, or nonprofessional, casual forgeries. Casual forgeries are by far the most prevalent type of forgery, resulting in large monetary losses nationwide.
A small number of training signatures are required to teach a neural network to perform the signature classification. Forgeries are required in the training set, but it is shown that true signatures of other subjects suffice as forgeries. In this way, actual forgeries need not be collected to train a network. The trained neural networks are tested on new signatures, resulting in an error rate of 3% rejection of true signatures as forgeries, and 3% acceptance of forgeries as true signatures.
The training sets for the signature verification networks are small, finite sets. The dynamic behavior of a neural network being trained on an infinite input set is well known, while being relatively unknown for the finite training sets. New theoretical results are presented here describing the behavior of a neural network that is trained on a finite size training set. Under special conditions, the optimal weights of a neural network are equivalent to the optimal weights of the synthetic discriminant function, which is another signal processing tool for performing classification.
The backpropagation learning algorithm for neural networks is examined in greater detail to reveal limits on the learning parameters. The mean square error performance surface is examined for a single nonlinear neuron, and shown to be similar to the performance surface for a single linear neuron, although there are choices of inputs and outputs which give rise to a performance surface that is very different from that of a single linear neuron. Lastly, an alternative to the backpropagation learning algorithm is presented which utilizes a step output function for binary classification. This modified algorithm is applied to the exclusive-or problem, which tests the networks ability to nonlinearly partition the input space. The modified algorithm learns the exclusive-or classification much faster and with fewer difficulties than the conventional backpropagation algorithm.
Threshold level laser photoablation of crystalline silver: Ejected ion translational energy distributions (1989)

We have conducted an experiment which measures, for a single laser shot, the ejected mass and nascent velocity distributions of ionic species ablated at laser fluences near the threshold for ion production. Our results show that for a crystalline silver target, the laser-ablated ion products are ejected with fixed kinetic energy equal to 9±1 eV (3 eV FWHM). The kinetic energy of the ejecta (Ag+,Ag+2, adsorbed Fe+) do not vary with wavelength (351 and 248 nm), nor with the ion product mass, and within limits are independent of the incident laser intensity. We do see a wavelength dependence in the threshold for ion production and in the dimer/monomer (Ag+/Ag+2) ion ratio. A number of possible mechanisms are presented to explain the data, although none is without some objection. Among these, the process whereby desorption is induced by electronic transitions (DIET processes) has some merit in explaining our data.
Exploiting Depth Discontinuities for Vision-Based Fingerspelling Recognition (2005)

We present a novel method for automatic fingerspelling recognition which is able to discriminate complex hand configurations with high amounts of finger occlusions. Such a scenario, while common in most fingerspelling alphabets, presents a challenge for vision methods due to the low intensity variation along important shape edges in the hand image. Our approach is based on a simple and cheap modification of the capture setup: a multi-flash camera is used with flashes strategically positioned to cast shadows along depth discontinuities in the scene, allowing efficient and accurate hand shape extraction. We then use a shift and scale invariant shape descriptor for fingerspelling recognition, demonstrating great improvement over methods that rely on features acquired by traditional edge detection and segmentation algorithms.
Optimized Attenuated Interaction: Enabling Stochastic Bethe-Salpeter Spectra for Large Systems (2023)

We develop an improved stochastic formalism for the Bethe-Salpeter equation, based on an exact separation of the effective-interaction $W$ to two parts, $W=(W-v_W)+v_W$ where the latter is formally any translationally-invariant interaction $v_W(r-r')$. When optimizing the fit of $v_W$ exchange kernel to $W$, by using a stochastic sampling of $W$, the difference $W-v_W$ becomes quite small. Then, in the main BSE routine, this small difference is stochastically sampled. The number of stochastic samples needed for an accurate spectrum is then largely independent of system size. While the method is formally cubic in scaling, the scaling prefactor is small due to the constant number of stochastic orbitals needed for sampling $W$.
Absence of stereoelectronic control in the photochemistry of two diastereomeric .beta.,.gamma.-epoxy ketones (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAbsence of stereoelectronic control in the photochemistry of two diastereomeric .beta.,.gamma.-epoxy ketonesSemiramis Ayral-Kaloustian and William C. AgostaCite this: J. Am. Chem. Soc. 1980, 102, 1, 314–323Publication Date (Print):January 1, 1980Publication History Published online1 May 2002Published inissue 1 January 1980https://pubs.acs.org/doi/10.1021/ja00521a050https://doi.org/10.1021/ja00521a050research-articleACS PublicationsRequest reuse permissionsArticle Views323Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts