gebhart/patrepeval huggingface dataset:
From the magnetic-field-driven transitions to the zero-field transition in two-dimensions (1999)

For more than a decade it was widely accepted that two-dimensional electrons are insulating at zero temperature and at zero magnetic-field. Experimentally it was demonstrated that, when placed in a strong perpendicular magnetic field, the insulating phase turns into a quantum-Hall state. While this transition was in accordance with existing theoretical models (KLZ), the density driven metal-insulator transition at zero magnetic-field, recently observed in high-quality two-dimensional systems, was unforeseen and, despite considerable amount of effort, its origins are still unknown. In order to improve our understanding of the zero magnetic-field transition, we conducted a study of the insulator to quantum-Hall transition in low-density, two-dimensional, hole system in GaAs that exhibits the zero magnetic-field metal-insulator transition. We found that, in the low field insulating phase, upon increasing the carrier density towards the metal-insulator transition, the critical magnetic-field of the insulator to quantum-Hall transition decreases and converges to the zero magnetic-field metal-insulator transition. This implies a common origin for both the finite magnetic-field and the zero magnetic-field transitions.
Allosteric Modulators of Nicotinic Acetylcholine Receptors Useful for the Treatment of Cognitive Impairment (2018)

ADVERTISEMENT RETURN TO ISSUEPREVPatent HighlightNEXTAllosteric Modulators of Nicotinic Acetylcholine Receptors Useful for the Treatment of Cognitive ImpairmentBenjamin E. Blass*Benjamin E. BlassTemple University School of Pharmacy, Moulder Center for Drug Discovery Research, Philadelphia, Pennsylvania 19140, United States*E-mail: [email protected]More by Benjamin E. BlassCite this: ACS Med. Chem. Lett. 2018, 9, 3, 163–164Publication Date (Web):February 5, 2018Publication History Received22 January 2018Published online5 February 2018Published inissue 8 March 2018https://pubs.acs.org/doi/10.1021/acsmedchemlett.8b00039https://doi.org/10.1021/acsmedchemlett.8b00039editorialACS PublicationsCopyright © 2018 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views1155Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (310 KB) Get e-AlertscloseSUBJECTS:Alkyls,Amines,Group 17 compounds,Nervous system diseases,Receptors Get e-Alerts
Weighted Sum Rate Maximization in Full-Duplex Multi-User Multi-Cell MIMO Networks (2017)

In this paper, we focus on a multi-user multi-cell scenario with full-duplex (FD) base-stations and half-duplex (HD) downlink (DL) and uplink (UL) users, where all nodes are equipped with multiple antennas. Our goal is to design filters for weighted sum rate (WSR) maximization whilst taking into consideration the effect of transmitter and receiver distortion. Since WSR problems are non-convex, we exploit the relationship between rate and mean squared error in order to propose low complexity alternating optimization algorithms, which are guaranteed to converge. While the initial design assumes perfect channel state information (CSI), we also move beyond this assumption and consider WSR problems under imperfect CSI. This is done using two types of error models; the first is a norm-bounded error model, suitable for cases where the CSI error is dominated by quantization issues, and the second is a stochastic error model, suitable for errors that occur during the channel estimation process itself. Results show that rates achieved in FD mode are higher than those achieved by the baseline HD schemes and demonstrate the robust performance of the proposed imperfect CSI designs. In addition, we also extend our original WSR problem to one which maximizes the total DL rate subject to each UL user achieving a desired target rate. This latter design can be used to overcome potential unfairness issues and ensure that all UL users are equally served in every time slot.
Emerging roles of the host defense peptide LL‐37 in human cancer and its potential therapeutic applications (2010)

Human cathelicidin LL-37, a host defense peptide derived from leukocytes and epithelial cells, plays a crucial role in innate and adaptive immunity. Not only does LL-37 eliminate pathogenic microbes directly but also modulates host immune responses. Emerging evidence from tumor biology studies indicates that LL-37 plays a prominent and complex role in carcinogenesis. Although overexpression of LL-37 has been implicated in the development or progression of many human malignancies, including breast, ovarian and lung cancers, LL-37 suppresses tumorigenesis in gastric cancer. These data are beginning to unveil the intricate and contradictory functions of LL-37. The reasons for the tissue-specific function of LL-37 in carcinogenesis remain to be elucidated. Here, we review the relationship between LL-37, its fragments and cancer progression as well as discuss the potential therapeutic implications of targeting this peptide.
Al-2.84 Negative-Tone Resist (2021)

As increasingly smaller molecular materials and material structures are devised or developed for technological applications, the demands on the processes of lithography now routinely include feature sizes that are of the order of 10 nm. In reaching such a fine level of resolution, the methods of lithography have increased markedly in sophistication and brought into play 2terminology that is unfamiliar, on the one hand, to scientists tasked with the development of new lithographic materials or, on the other, to the engineers who design and operate the complex equipment that is required in modern-day processing. Publications produced by scientists need to be understood by engineers and vice versa, and these commonly arise from collaborative research that draws heavily on the terminology of two or more of the traditional disciplines. It is developments in polymer science and material science that lead progress in areas that cross traditional boundaries, such as microlithography. This document provides the exact definitions of a selection of unfamiliar terms that researchers and practitioners from different disciplines might encounter.
375  km Urban Field Trial of OFDMA-PON Using Colorless ONUs With Dynamic Bandwidth Allocation and TCM [Invited] (2014)

The orthogonal frequency division multiple access (OFDMA)-based passive optical network (PON) is a potential candidate to meet the flexibility requirements for next-generation optical access networks. We propose an OFDMA-based PON with a transmission employing intensity modulation/direct detection in the downstream and a remodulation of a remotely seeded carrier provided by the optical line terminal with coherent detection in the upstream, which enables cost-effective colorless optical network units (ONUs). Furthermore, an OFDMA-PON field trial using the proposed scheme over 37.5&#xA0;km feeder fiber is demonstrated. A power budget supporting 32 ONUs with dynamic bandwidth allocation and trellis coded modulation (TCM) is reported.
EXTENSOR MECHANISM REPAIR: A SYNTHETIC MESH ALTERNATIVE (2015)

Complications involving the knee extensor mechanism occur in 1% to 12% of patients following total knee arthroplasty (TKA), and have negative effects on patient outcomes. While multiple reconstruction options have been described for complete disruption of the extensor mechanism, the results in patients with a prior TKA are inferior to those in patients without a TKA, and frequently have required the use of allograft tendon grafts which can attenuate and stretch over time. However, encouraging results have been reported by Browne and Hanssen in treatment of patellar tendon disruption with the use of a synthetic mesh (knitted monofilament polypropylene). In this technique, a synthetic graft is created by folding a 10 × 14 inch sheet of mesh and securing it with non-absorbable sutures. A burr is then used to create a trough in the anterior aspect of the tibia to accept the mesh graft. The graft is inserted into the trough and secured with cement. After the cement cures, a transfixion screw with a washer is placed. A portal is subsequently created in the soft tissues lateral patellar tendon remnants to allow delivery of the graft from deep to superficial. The patella and quadriceps tendon are mobilised, and the graft is secured with sutures to the lateral retinaculum, vastus lateralis, and quadriceps tendon. The vastus medialis is then mobilised and brought in a pants-over-vest manner over the mesh graft, and secured with additional sutures. Finally, the distal arthrotomy is closed tightly to completely cover the mesh graft with host tissue. In their series, Browne and Hanssen noted that 9 of 13 patients achieved an extensor lag of
Influence of thermal annealing on CdTe thin film deposited by thermal evaporation technique (2014)

Effects of thermal annealing on the structural and optical properties of thermally evaporated CdTe thin films are presented here. Thin films of CdTe were deposited on soda lime glass substrates at room temperature by varying the deposition current ranging from 25 Amperes to 30 Amperes by thermal evaporation. The grown samples were annealed at the annealing temperature of 400°C for 15 minutes in a vacuum furnace of nitrogen ambient with pressure of 250–300 mTorr. The structural, optical and electrical properties of the grown samples were investigated by XRD, AFM and UV-VIS spectrometry. The as-deposited films prepared at deposition current 25A shows polycrystalline nature whereas the films prepared at 28A and 30A exhibit cubic crystallinity with (111) preferential orientation around 2θ=23.8°. The surface roughness of the films is also highly affected by the thermal annealing as observed from the AFM images. The band gap has been found around 1.5 eV for the as-deposited film whereas the band gap decreased approximately to 1.4 eV after thermal annealing treatment.
A Competitive Mean-Squared Error Approach to Beamforming (2007)

We treat the problem of beamforming for signal estimation where the goal is to estimate a signal amplitude from a set of array observations. Conventional beamforming methods typically aim at maximizing the signal-to-interference-plus-noise ratio (SINR). However, this does not guarantee a small mean-squared error (MSE), so that on average the resulting signal estimate can be far from the true signal. Here, we consider strategies that attempt to minimize the MSE between the estimated and unknown signal waveforms. The methods we suggest all maximize the SINR but at the same time are designed to have good MSE performance. Since the MSE depends on the signal power, which is unknown, we develop competitive beamforming approaches that minimize a robust MSE measure. Two design strategies are proposed: minimax MSE and minimax regret. We demonstrate through numerical examples that the suggested minimax beamformers can outperform several existing standard and robust methods, over a wide range of signal-to-noise ratio (SNR) values. Finally, we apply our techniques to subband beamforming and illustrate their advantage in estimating a wideband signal.
High-Sensitivity Cardiac Troponin T for Early Prediction of Evolving Non–ST-Segment Elevation Myocardial Infarction in Patients with Suspected Acute Coronary Syndrome and Negative Troponin Results on Admission (2010)

The high-sensitivity cTnT assay increases the number of NSTEMI diagnoses and enables earlier detection of evolving NSTEMI. A doubling of the hs-cTnT concentration within 3 h in the presence of a second concentration >or=99th percentile is associated with a positive predictive value of 100% and a negative predictive value of 88%.
Obtaining Nernstian Response of a Ca2+-Selective Electrode in a Broad Concentration Range by Tuned Galvanostatic Polarization (2008)

Linear Nernstian response is obtained for a neutral ionophore-based Ca(2+)-selective electrode down to 10(-10) M CaCl2 by means of galvanostatic polarization. The densities of the applied cathodic current were tuned for particular concentrations of Ca2+. The procedure included recording the potential at zero current, followed by measurements when current is passed through the electrode, and then again at zero current. The respective chronopotentiometric curves included negative ohmic drop immediately after turning the current on, the polarization domain, and positive ohmic drop when the current was turned off, followed with the relaxation domain. The potentials immediately after the positive ohmic drops were used as analytical signals. These potentials make a straight line with Nernstian slope when currents are tuned (optimized) for each particular concentration. An iteration procedure is proposed which allows for simultaneous optimization of the current density and accessing analyte concentration in the sample.
2017 EACTS/EACTA Guidelines on patient blood management for adult cardiac surgery (2017)

Complex and redo operation, severe renal insufficiency, haematological diseases and hereditary deficiencies in platelet function. e Mechanical prosthetic heart valve, atrial fibrillation with rheumatic valvular disease, an acute thrombotic event within the previous 4 weeks and atrial fibrillation with a CHA 2 DS 2 -VASc score >4. ASA: acetylsalicylic acid; CABG: coronary artery bypass grafting; CHA 2 DS 2 -VASc: congestive heart failure, hypertension, age > _75 (2 points), diabetes, prior stroke (2 points) -vascular disease, age 65-74, sex category (female); DAPT: dual antiplatelet therapy; DOAC: direct oral anticoagulant; GP: glycoprotein; INR:
Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways inStreptomyces coelicolorusing DNA microarrays (2001)

The eubacterial species Streptomyces coelicolor proceeds through a complex growth cycle in which morphological differentiation/development is associated with a transition from primary to secondary metabolism and the production of antibiotics. We used DNA microarrays and mutational analysis to investigate the expression of individual genes and multigene antibiotic biosynthetic pathways during these events. We identified expression patterns in biosynthetic, regulatory, and ribosomal protein genes that were associated highly specifically with particular stages of development. A knowledge-based algorithm that correlates temporal changes in expression with chromosomal position identified groups of contiguous genes expressed at discrete stages of morphological development, inferred the boundaries of known antibiotic synthesis gene loci, and revealed novel physical clusters of coordinately regulated genes. Microarray analysis of RNA from cells mutated in genes regulating synthesis of the antibiotics actinorhodin (Act) and undecylprodigiosin (Red) identified proximate and distant sites that contain putative ABC transporter and two-component system genes expressed coordinately with genes of specific biosynthetic pathways and indicated the existence of two functionally and physically discrete regulons in the Red pathway.
FRACTIONATION OF FELINE BONE MARROW WITH THE SOYBEAN AGGLUTININ LECTIN YIELDS POPULATIONS ENRICHED FOR ERYTHROID AND MYELOID ELEMENTS (1997)

Feline bone marrow cells treated with the soybean agglutinin (SBA) lectin are separated into two populations, the agglutinated SBA(+) fraction containing predominantly cells of myeloid origin and the nonagglutinated SBA(-) fraction consisting of cells primarily of the erythroid lineage. FACScan analyses revealed a clear distinction of the cells based on their light scattering properties, i.e., large cells and cells with high granularity were found in the SBA(+) fraction, whereas cells having a low forward light scatter and side light scatter were found in the SBA(-) fraction. Colony-forming assays showed colony-forming unit-granulocyte/monocyte (CFU-GM) cells to have a strong affinity for SBA because these were found almost entirely in the SBA(+) fraction; in contrast, burst-forming unit-erythroid (BFU-E)-forming cells were concentrated in the SBA(-) fraction. When the marrow was fractionated by counterflow centrifugal elutriation (CCE), a differential binding to SBA among the CFU-GM forming cells was found. The SBA(-) fractions of cells collected at 21 and 25 ml/min contained primarily BFU-E forming cells, similar to that observed with whole marrow; the later CCE fractions, those collected at 32 ml/min and the rotor off fraction, when treated with SBA showed a small but significant number of CFU-GM cells in the SBA(-) fraction. T lymphocytes were found predominantly in the SBA(+) fractions of whole bone marrow and the CCE fractions. Successful autologous marrow transplants were performed with the early CCE SBA(-) fractions. The latter cells were used for our initial transplant attempts because ongoing studies in our laboratory had shown these cells to be free of any viral-containing cells when the marrow had been obtained from animals infected with the feline immunodeficiency virus. In summary, although SBA treatment of feline marrow yields a marked separation of CFU-GM and BFU-E progenitors, select CCE SBA(-) fractions contain stem cells capable of providing hematopoietic reconstitution of lethally irradiated animals.
Extremely-thin-body InGaAs-on-insulator MOSFETs on Si fabricated by direct wafer bonding (2010)

We have demonstrated extremely-thin-body (ETB) (3.5 and 9 nm) InGaAs-on-insulator (InGaAs-OI) MOSFETs on Si substrates with Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> ultrathin buried oxide (UTBOX) layers fabricated by direct wafer bonding (DWB). We have found that the ETB highly-doped InGaAs-OI n-channel MOSFETs without p-n junction can perform a normal MOSFET operation under front- and back-gate configuration and the double-gate operation can provide excellent on-current/off-current (I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">on</sub> /I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">off</sub> ) properties of ~10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">7</sup> and the improved S factor even for InGaAs-OI MOSFETs with N <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">D</sub> of 1×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">19</sup> cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-3</sup> .
WOUND DIAGNOSTICS WITH MICROWAVES (2002)

The reflection of electromagnetic waves on material surfaces is very depending on the electric and magnetic properties of these materials, on their structure and on the surface texture. Therefore the different layers and dielectric properties of healthy and unsound body tissue also show different reflection behavior towards incidentating electromagnetic waves. By analyzing the reflected signals of incident electromagnetic waves, it is possible to get information about the inner structure of the reflecting body tissue. This effect could then be used for a contactless analysis of body tissue e.g. to gain crucial medical information about healing processes. In this paper the results of several full wave simulations of various tissue structures are presented and the significance and usability of this method is shown.
V<sub>fb</sub> Lowering Effect of TaC/Rare Earth Metal/TaC Laminated Gate Electrode Applicable to N-MISFET with HfSiON and its Physical Origins before and after High-Temperature Annealing (2008)

2008 International Conference on Solid State Devices and Materials,V<sub>fb</sub> Lowering Effect of TaC/Rare Earth Metal/TaC Laminated Gate Electrode Applicable to N-MISFET with HfSiON and its Physical Origins before and after High-Temperature Annealing
Acoustothermal tweezer for droplet sorting in a disposable microfluidic chip (2017)

Precise control over droplet position within a microchannel is fundamental to droplet microfluidic applications. This article proposes acoustothermal tweezer for the control of droplet position, which is based on thermocapillary droplet migration actuated by acoustothermal heating. The proposed system comprises an acoustothermal heater, which is composed of a slanted finger interdigital transducer patterned on a piezoelectric substrate and a thin PDMS membrane, and a PDMS microchannel. In the proposed system, droplets moving in a droplet microfluidic chip experience spatiotemporally varying thermal stimuli produced by acoustothermal heating and thus migrate laterally. In comparison to previous methods for droplet sorting, the acoustothermal tweezer offers significant advantages: first, the droplet position can be manipulated in two opposite directions, which enables bidirectional droplet sorting to one of three outlets downstream; second, precise control over the droplet position as well as improved droplet lateral displacement on the order of hundreds of micrometers can be achieved in a deterministic manner, thereby enabling multichannel droplet sorting; third, the PDMS microfluidic chip is disposable and thus can be easily replaced since it is attached to the substrate by reversible bonding, which allows the acoustothermal heater to be reused. Given these advantages, the proposed droplet sorting system is a promising droplet microfluidic lab-on-a-chip platform for tunable, on-demand droplet position control.
Synthesis of Zerovalent Nanophase Metal Particles Stabilized with Poly(ethylene glycol) (2004)

Concurrent sonolysis of iron pentacarbonyl and poly(ethylene glycol)-400 (PEG-400) in hexadecane solvent proceeds via zero-order kinetics and results in Fe nanoparticles encapsulated in PEG-400 (Fe-PEG). The transmission electron microscopy images show Fe-PEG consisting of <3 nm Fe particles that are evenly dispersed in the PEG matrix. Mössbauer and X-ray absorption fine structure/X-ray absorption near-edge structure data reveal an ordered PEG assembly that helps protect the zerovalent Fe core. The Fe nanoparticles in Fe-PEG are superparamagnetic with a magnetization value of 45 emu/g-Fe at 10 KOe. The rheology of the synthesized material shows an unusual increase in viscosity with temperature that is likely due to lower critical saturation temperature phase segregation over 40 degrees C. The low-temperature mobility of the PEG-400 moiety in Fe-PEG would allow facile ligation of the Fe0 core with biologically and chemically active groups.