gebhart/patrepeval huggingface dataset:
A Broadcast Protocol for File Transfers to Multiple Sites (1981)

A retransmission Protocol for a broadcast connection (point-to-multipoint) is proposed and its performance characteristics are considered. The protocol is designed for transfers of large files Over a satellite channel that is time-shared to carry both the data from the broadcasting transmitter and the set of acknowledgments from the multiple receiver sites. A mathematical model of the transmission system that includes separate error processes for uplink and downlink errors on data transmissions, and similar processes for errors on the acknowledgment frames as well, is used to analyze the performance of the scheme. Exact analytical expressions for the relative throughput of the channel are obtained for two special cases: 1) the uplink is error-free; and 2) the acknowledgments are error-free. For the general case, upper and lower bounds are derived and are shown to be virtually indistinguishable for many practical sets of system parameters. The results demonstrate that the broadcasting of large files to multiple receivers can be done both efficiently and reliably.
Screening for compensated advanced chronic liver disease using refined Baveno VI elastography cutoffs in Asian patients with nonalcoholic fatty liver disease (2021)

The dual elastography cutoffs of 8 and 12 kPa are more appropriate to identify cACLD in Asian patients with NAFLD. In combination with a simplified risk model in unclassified patients, the two-step approach showed a classification rate of about 85%.
Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism (2016)

Lysophospholipase-like 1 (LYPLAL1) is an uncharacterized metabolic serine hydrolase. Human genome-wide association studies link variants of the gene encoding this enzyme to fat distribution, waist-to-hip ratio, and nonalcoholic fatty liver disease. We describe the discovery of potent and selective covalent small-molecule inhibitors of LYPLAL1 and their use to investigate its role in hepatic metabolism. In hepatocytes, selective inhibition of LYPLAL1 increased glucose production supporting the inference that LYPLAL1 is a significant actor in hepatic metabolism. The results provide an example of how a selective chemical tool can contribute to evaluating a hypothetical target for therapeutic intervention, even in the absence of complete biochemical characterization.
GENDER SPECIFIC CYTOGENETIC SIGNATURES CAN DISTINGUISH BETWEEN ONCOCYTOMA AND CHROMOPHOBE RENAL CELL CARCINOMA (2008)

You have accessJournal of Urology1 Apr 2008GENDER SPECIFIC CYTOGENETIC SIGNATURES CAN DISTINGUISH BETWEEN ONCOCYTOMA AND CHROMOPHOBE RENAL CELL CARCINOMA Tobias Klatte, P Nagesh Rao, Michela De Martino, Jonathan W Said, Brian Shuch, Jeffrey LaRochelle, Fairooz F Kabbinavar, Arie S Belldegrun, and Allan J Pantuck Tobias KlatteTobias Klatte More articles by this author , P Nagesh RaoP Nagesh Rao More articles by this author , Michela De MartinoMichela De Martino More articles by this author , Jonathan W SaidJonathan W Said More articles by this author , Brian ShuchBrian Shuch More articles by this author , Jeffrey LaRochelleJeffrey LaRochelle More articles by this author , Fairooz F KabbinavarFairooz F Kabbinavar More articles by this author , Arie S BelldegrunArie S Belldegrun More articles by this author , and Allan J PantuckAllan J Pantuck More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(08)60487-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "GENDER SPECIFIC CYTOGENETIC SIGNATURES CAN DISTINGUISH BETWEEN ONCOCYTOMA AND CHROMOPHOBE RENAL CELL CARCINOMA." The Journal of Urology, 179(4S), pp. 168–169 © 2008 by American Urological AssociationFiguresReferencesRelatedDetails Volume 179Issue 4SApril 2008Page: 168-169 Advertisement Copyright & Permissions© 2008 by American Urological AssociationMetricsAuthor Information Tobias Klatte More articles by this author P Nagesh Rao More articles by this author Michela De Martino More articles by this author Jonathan W Said More articles by this author Brian Shuch More articles by this author Jeffrey LaRochelle More articles by this author Fairooz F Kabbinavar More articles by this author Arie S Belldegrun More articles by this author Allan J Pantuck More articles by this author Expand All Advertisement PDF downloadLoading ...
Pulsed Metalorganic chemical vapor deposition of transition metal oxydes (2005)

International audience
Gold-doped silver nanoclusters with enhanced photophysical properties (2018)

We detail the characterization of atomically precise, luminescent silver and gold bimetallic nanoclusters (Ag and AgAuNCs) grown in the presence of bidentate lipoic acid (LA, the oxidized form) and dihydrolipoic acid (DHLA, the reduced form) ligands. We found that while doping AuNCs with Ag or Cu precursors using up to a 50% molar fraction (during growth) did not lead to any photoluminescence enhancement, doping of AgNCs with Au resulted in a six-fold enhancement of the PL emission compared to undoped AgNCs. The effect of doping is also reflected in the optical absorption and PL excitation spectra of the gold-doped NCs (AgAuNCs), where a clear blue shift in the absorbance features with respect to the pure AgNCs has been measured. Mass spectrometry measurements using ESI-MS showed that the AgNCs and Au-doped AgNCs had the compositions Ag29(DHLA)12 and Ag28Au(DHLA)12, respectively. The bimetallic nature of the AgAuNC cores was further supported by X-ray Photoelectron Spectroscopy (XPS) measurements. Data showed that the binding energies of the Ag and Au atoms measured from the nanoclusters were shifted with respect to those of the Ag and Au metals. Furthermore, the change in the Ag binding energy was affected by the presence of Au atoms. DOSY-NMR measurements performed on both sets of nanoclusters yielded no change in the hydrodynamic radius measured for either set of NCs when capped with the same ligands.
Architektur im Informationsterritorium — ein Experiment (1996)

Architektur im Informationsterritorium ist eine radikale Alternative zur bestehenden physischen Architektur. Im Informationsterritorium ist Information der bedeutendste Rohstoff, die Realität des Informationsterritoriums ist die virtuelle Realität, und der Computer ist zugleich Instrument, Infrastruktur und Entwurfsumgebung. Er ist zum Partner avanciert, der eine bestimmte Verantwortung übernimmt und verschiedene Aufträge selbständig ausführt.
Development of Cannabinoids in Flowers of Industrial Hemp (Cannabis sativa L.): A Pilot Study (2020)

A field study was performed to investigate the development of cannabinoids in flowers of industrial hemp using three day-length-sensitive and two day-length-neutral varieties. Flower samples were analyzed for cannabinoids on a weekly basis from 2 to 4 weeks postanthesis to plant senescence. Results indicate that total THC, CBD, and CBG significantly increased as flowers matured, reaching the greatest concentration during 6 to 7 weeks postanthesis. After a plateau stage of varied length for different varieties, the peak concentrations declined as plants senesced. Total THC was above the 0.3% threshold from 4 weeks postanthesis to the end of the growing season for day-length-sensitive varieties, but this only occurred during 6 to 7 weeks postanthesis for day-length-neutral varieties. The CBD/THC ratio in flowers dynamically changed during the entire reproductive stage for all of the evaluated varieties. The current study provides vital information for successful cultivation of industrial hemp.
Hybrid evolutionary algorithms for network-centric command and control (2006)

Network-centric force optimization is the problem of threat engagement and dynamic Weapon-Target Allocation (WTA) across the force. The goal is to allocate and schedule defensive weapon resources over a given period of time so as to achieve certain battle management objectives subject to resource and temporal constraints. The problem addresses in this paper is one of dynamic WTA and involves optimization across both resources (weapons) and time. We henceforth refer to this problem as the Weapon Allocation and Scheduling problem (WAS). This paper addresses and solves the WAS problem for two separate battle management objectives: (1) Threat Kill Maximization (TKM), and (2) Asset Survival Maximization (ASM). Henceforth, the WAS problems for the above objectives are referred to as the WAS-TKM and WAS-ASM, respectively. Both WAS problems are NP-complete problem and belong to a class of multiple-resource-constrained optimal scheduling problems. While the above objectives appear to be intuitively similar from a battle management perspective, the two optimal scheduling problems are quite different in their complexity. We present a hybrid genetic algorithm (GA) that is a combination of a traditional genetic algorithm and a simulated annealing-type algorithm for solving these problems. The hybrid GA approach proposed here uses a simulated annealing-type heuristics to compute the fitness of a GA-selected population. This step also optimizes the temporal dimension (scheduling) under resource and temporal constraints and is significantly different for the WAS-TKM and WAS-ASM problems. The proposed method provides schedules that are near optimal in short cycle times and have minimal perturbation from one cycle to the next.
Initial operating experience of the 1.2-MW La Ola photovoltaic system (2012)

The 1.2-MW La Ola photovoltaic (PV) power plant in Lanai, Hawaii, has been in operation since December 2009. The host system is a small island microgrid with peak load of 5 MW. Simulations conducted as part of the interconnection study concluded that unmitigated PV output ramps had the potential to negatively affect system frequency. Based on that study, the PV system was initially allowed to operate with output limited to 50% of nameplate power capacity to reduce the potential for frequency instability due to PV variability. Based on the analysis of historical voltage, frequency, and power output data at 50% output level, the PV system has not significantly affected grid performance. However, it should be noted that the impact of PV variability on active and reactive power output of the nearby diesel generators was not evaluated.
Noise suppressed, multifocus image fusion for enhanced intraoperative navigation (2012)

Current intraoperative imaging systems are typically not able to provide 'sharp' images over entire large areas or entire organs. Distinct structures such as tissue margins or groups of malignant cells are therefore often difficult to detect, especially under low signal-to-noise-ratio conditions. In this report, we introduce a noise suppressed multifocus image fusion algorithm, that provides detailed reconstructions even when images are acquired under sub-optimal conditions, such is the case for real time fluorescence intraoperative surgery. The algorithm makes use of the Anscombe transform combined with a multi-level stationary wavelet transform with individual threshold-based shrinkage. While the imaging system is integrated with a respiratory monitor triggering system, it can be easily adapted to any commercial imaging system. The developed algorithm is made available as a plugin for Osirix.
Figure S5 from The Transcriptional Regulator Sin3A Contributes to the Oncogenic Potential of STAT3 (2023)

&lt;p&gt;Data reproduce the effect of Sin3A deletion with a second shRNA&lt;/p&gt;
Design of complementary GAA-NW tunneling-FETs of axial Si-Ge heterostructure (2010)

With sub-16nm CMOS nodes looming, this work proposes a novel device structure for Gate-All-Around (GAA), Nanowire (NW) tunneling-FET (tFET), with axial heterojunction on the source-channel junction, gate-underlap on the drain end of the channel, and optimized doping levels of source and drain. This structure successfully suppresses the undesirable ambipolar transfer characteristics of conventional tFETs, while maintaining the advantage of small subthreshold swing of less than 60mV/dec. For the first time, an all-tFET inverter is demonstrated to exhibit excellent switching behaviors, out-performing both the homojunction Si NW-tFET and the conventional CMOS in inverters with the same gate length and supply voltage.
Association of colorectal cancer intrinsic subtypes with prognosis, chemotherapy response, deficient mismatch repair, and epithelial to mesenchymal transition (EMT). (2013)

333 Background: Unbiased genome-wide analyses of gene expression patterns have been successfully used for the molecular classification of breast cancer into subtypes that have clear relevance for prognosis and development of treatment plans. For colorectal cancer (CRC), however, a molecular classification is still missing. Methods: Using gene expression data of 188 stage I-IV colorectal cancer (CRC) patients, a molecular subtype classification was developed. The classifier was validated in 543 stage II and III patients and the subtypes were analyzed for correlation to clinical information, mutations in the kinome, known molecular marker status and chemotherapy response. Results: CRC is a heterogeneous disease that consists of at least three major intrinsic subtypes (A-, B-, C-type). The heterogeneity of the intrinsic subtypes is largely based on three biological hallmarks of the tumor: an epithelial-to-mesenchymal transition, deficiency in mismatch repair genes that result in a high mutation frequency associated with MSI, and cellular proliferation. C-type patients have the worst outcome, a mesenchymal gene expression phenotype, and show no benefit from adjuvant chemotherapy treatment. Patients having A-type or B-type tumors have a better clinical outcome, a more proliferative and epithelial phenotype, and benefit from adjuvant chemotherapy. B-type tumors showed a low overall kinome mutation frequency (1.6%), while both A-type and C-type patients harbor a higher mutation frequency (respectively 4.2 and 6.2%), in agreement with their mismatch repair deficiency. Conclusions: We have developed a diagnostic single sample predictor that allows the classification of CRC tumors of different intrinsic molecular subtypes. These subtypes are potentially clinically relevant, as they differ in their underlying biology and clinical outcome and consequently require different treatment strategies. [Table: see text]
Development and Validation of a 3-Dimensional Flexible Laryngoscopy Training Simulator (2022)

The objective of this study was to validate the use of a 3-Dimensional Flexible Laryngoscopy Training Simulator. This is a simulation device development and validation study. Anonymized CT scan data from a head/neck CT of a patient with normal anatomy was imported and a head/neck digital model was created. A 3D simulation model was printed using a stiff (Stratasys Vero) and flexible (Stratasys Agilus) material combination with a ShoreA hardness value of 60. Novices and experts were instructed and provided 5 trials to pass the laryngoscope. The videos of the first and the last trial were recorded and evaluated by three different evaluators. Performances were measured by the amount of time spent and precision of the task. Repeated measures of ANOVA and generalized linear model with binomial proportion was used were utilized to analyze the data. The post training scores were statistically significantly higher than pre training scores (Mean: 15.57 vs. 13.01, p &lt;0.0001) controlling for trainee experience. The time taken to complete a successful pass post training was statistically significantly lesser than pre training (Mean: 62.55 secs vs. 36.36 secs, p-value = 0.0007) controlling for individual’s experience. The odds of becoming skilled at the task was 4 times higher post training in comparison to pre training, controlling for individual’s experience (OR: 4.05, p-value: 0.0026). The 3-Dimensional Flexible Laryngoscopy Training Simulator is a valid trainer for both novice and experienced individuals. The simulator can improve technical skill performance and is critical for medical training.
Comparative microsatellite analysis in discerning origin of disseminated tumor: The case of a patient with malignant ascites and a history of multiple tumors (1999)

The origin of metastatic carcinoma is now always easily resolved on the basis of conventional dinical and pathological parameters, particularly in patients with more than 1 primary tumor. When 1 of the tumors is a renal cell carcinoma, the clinical picture is further confounded by the tendency of these tumors to be locally silent, to metastasize to unusual sites, and to disseminate long after removal of the primary tumor. We compared tumors for loss (ie, deletion) of loci on chromosomal arms 3p, 5q, 11q, and 18q in a patient with a malignant ascites fluid, a remote history of renal and colonic neoplasms, and a strong clinical suspicion of disseminated gastrointestinal adenocarcinoma. DNA from microdissected tumors and normal tissues was subjected to polymerase chain reaction-based microsatellite analysis. Even though the clinical picture suggested a gastrointestinal origin, comparison of genetic alterations clearly showed that the malignant ascites represented recurrence of the renal cell carcinoma. The malignant ascites and the primary renal cell carcinoma showed identical patterns of allelic loss at all loci tested. In contrast, the malignant ascites and colonic adenoma showed discordant patterns of allelic loss. Comparative microsatellite analysis provides a rapid genetic approach for discerning the origin of metastatic tumor spread. This may be a useful diagnostic adjunct when tumor origin is not clear on clinical or morphological grounds. In some instances, it may even provide a reasonable alternative to an extensive and costly conventional work-up.
Free-space orbital angular momentum division multiplexing with Bessel beams (2011)

We present an apparatus for multiplexing and demultiplexing free-space beams carrying different values of orbital angular momentum (OAM), at a wavelength of 633 nm. We have considered nondiffracting Bessel beams of order from 0 to 3, produced by means of suitable binary-amplitude computer-generated holograms and carrying an OAM per photon directly proportional to the beam order. The effectiveness of the OAM division multiplexing technique has been experimentally verified by monitoring the output ports of a demultiplexing interferometer with rotated Dove prisms in the arms.
Electrogenic transport by lipophilic guanidinium salts as anion carriers in bilayer membranes (2017)

Anion transport by four isomers of tetradecylguanidinium in vesicle bilayer membranes was investigated by ion-selective electrode and pH-sensitive fluorescence methods. On a macroscopic scale, these carriers mediate hydroxide-anion antiport. In the absence of an externally imposed ionic gradient, the carriers produce a pH gradient due to rapid partition-deprotonation of the carrier and diffusion of the guanidine conjugate base. The formally coupled anion transport is slow relative to this process, and the system exhibits a corresponding membrane polarisation detected with potential-sensitive fluorescent dyes. Selective anion transport in competition with the efficient hydroxide transport is detected only with relatively easily extracted anions and N,N′-disubstituted isomers. Membrane polarisation changes can be deduced from simple equivalent circuits derived from the Goldman–Hodgkin–Katz voltage equation.
Optimum catalyst selection over continuous and discrete process variables with a single droplet microfluidic reaction platform (2018)

A mixed-integer nonlinear program (MINLP) algorithm to optimize catalyst turnover number (TON) and product yield by simultaneously modulating discrete variables—catalyst types—and continuous variables—temperature, residence time, and catalyst loading—was implemented and validated.
SAVE: Sparsity-Aware Vector Engine for Accelerating DNN Training and Inference on CPUs (2020)

General Matrix Multiplication (GEMM) is the key operation in Deep Neural Networks (DNNs). While dense GEMM uses SIMD CPUs efficiently, sparse GEMM is much less efficient, especially at the modest levels of unstructured sparsity common in DNN inference/training. Thus, most DNNs use dense GEMM.In this paper, we propose SAVE, a novel vector engine for CPUs that efficiently skips ineffectual computation due to sparsity in dense DNN implementations. SAVE's hardware extensions to the vector pipeline are transparent to software. SAVE accelerates FP32 and mixed-precision kernels with unstructured sparsity from both weights and activations. Further, SAVE is not DNN-specific and can potentially speed-up any vector workload with sparsity. To evaluate SAVE, we use simulations of a 28-core machine and run VGG16, ResNet-50, and GNMT, with and without pruning. With realistic sparsity, SAVE accelerates inference by 1.37x-1.68x and end-to-end training by 1.28x-1.64x.
Photochemistry of perester initiators (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPhotochemistry of perester initiatorsLambertus Thijs, Satyendra N. Gupta, and Douglas C. NeckersCite this: J. Org. Chem. 1979, 44, 23, 4123–4128Publication Date (Print):November 1, 1979Publication History Published online1 May 2002Published inissue 1 November 1979https://pubs.acs.org/doi/10.1021/jo01337a023https://doi.org/10.1021/jo01337a023research-articleACS PublicationsRequest reuse permissionsArticle Views264Altmetric-Citations48LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Au-Assisted catalytic growth of Si2Te3 plates (2019)

We synthesized Si<sub>2</sub>Te<sub>3</sub> plates on Si substrates using Au particles as catalyst. The Au particles enabled the liquid phase reaction with Si and Te due to the eutectic alloy formation of Au–Si and Au–Te.
(Rp)-1-{(R)-(Dimethylamino)[2-(diphenylphosphanyl)phenyl]methyl}-2-(diphenylphosphanyl)ferrocene chloroform solvate (2008)

The absolute configuration of the title mol-ecule, [Fe(C(5)H(5))(C(38)H(34)NP(2))]·CHCl(3), is R,R(p). The mol-ecular structure is similar to the structure of the solvent-free compound [Fukuzawa, Yamamoto & Kikuchi (2007 ▶). J. Org. Chem. 72, 1514-1517], but some torsion angles about the P-C(phen-yl) bonds differ by up to 25°. The P atoms and the N atom have a distorted trigonal-pyramidal geometry. The chloro-form solvate group donates a C-H⋯π bond to the central benzene ring and is also involved in six inter-molecular C-H⋯Cl contacts with H⋯Cl distances between 2.96 and 3.13 Å.
Economic Impact of Remote Patient Monitoring: An Integrated Economic Model Derived from a Meta-Analysis of Randomized Controlled Trials in Heart Failure (2010)

The novel cost-effectiveness data coupled with the demonstrated clinical efficacy of RPM should encourage its acceptance amongst clinicians and its consideration by third-party payers. At the same time, the scientific community should acknowledge the lack of prospectively and uniformly collected economic data and should request that future studies incorporate economic analyses.