gebhart/patrepeval huggingface dataset:
Multicenter clinical trial of high‐intensity focused ultrasound treatment in glaucoma patients without previous filtering surgery (2015)

The UC(3) procedure seems to be an effective and well-tolerated method to reduce IOP in patients with open-angle glaucoma without previous filtering surgery.
Poster presentation (2011)

Background/objectives: Even though catheter ablation is the established curative therapy for paediatric tachyarrhythmias, exposure to ionizing radiation from fluoroscopy during the procedure is of concern to both patients and caregivers. We sought to assess the impact of an impedance-based three-dimensional navigation system (NavXTM, Endocardial Solutions, Inc., St Paul, MN, USA) on paediatric catheter ablation fluoroscopy times. Methods: We retrospectively analysed the procedural data during a 7-year period (2002)(2003)(2004)(2005)(2006)(2007)(2008), which spanned the transition between the standard fluoroscopic mapping and adoption of routine NavXTM mapping for catheter ablation of atrioventricular nodal re-entrant tachycardia (AVNRT) and right-/left-sided accessory pathways (RAP/LAP). Comparisons of total procedure time, total fluoro time, and ablation fluoro time (from insertion of ablation catheter until completion of procedure) between NavXTM and conventional mapping were made. Results: A total of 388 patients (aged 1 -18 years, M:F 236:183) underwent ablation of AVNRT (n 101), LAP (n 130), or RAP (n 157) using either CONV (n 70) or NavXTM (n 318) mapping. Overall, success rates were similar between the two mapping systems (95.7% for conventional vs. 95.9% for NavXTM). NavXTM mapping significantly reduced the ablation fluoro time (15.9 + 14.3 min vs. 11.0 + 8.9 for NavXTM, P , 0.01) with a trend towards a decrease in total fluoro time (26.4 + 15.6 min vs. 23.8 + 11.1 for NavXTM, P 0.095). The total procedure time was not significantly different between the two methods (210.1 + 66 vs. 222.8 + 61 min for NavXTM, P 0.7). When analysed by arrhythmia substrate, there were significant reductions in the ablation fluoro time for both LAP and RAP. Conclusion: NavXTM mapping reduced ablation fluoro times during paediatric catheter ablation, particularly in accessory pathways.
Tribophosphorescence from nonphotophosphorescent crystals (1974)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTribophosphorescence from nonphotophosphorescent crystalsJeffrey I. ZinkCite this: J. Am. Chem. Soc. 1974, 96, 21, 6775–6777Publication Date (Print):October 1, 1974Publication History Published online1 May 2002Published inissue 1 October 1974https://pubs.acs.org/doi/10.1021/ja00828a048https://doi.org/10.1021/ja00828a048research-articleACS PublicationsRequest reuse permissionsArticle Views113Altmetric-Citations18LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Achieving conformational control over C–C, C–N and C–O bonds in biaryls, N,N′-diarylureas and diaryl ethers: advantages of a relay axis (2007)

The orientation of Ar-C, Ar-N and Ar-O bonds in biaryls, N,N'-diarylureas and diaryl ethers (whose conformers are distinguishable by NMR) may be controlled with a selectivity up to >95 : 5 by an adjacent stereogenic centre; the selectivity may be greater when a second stereogenic axis is inserted between the controlling centre and the slowly rotating bond.
Normative Findings of Electrically Evoked Compound Action Potential Measurements Using the Neural Response Telemetry of the Nucleus CI24M Cochlear Implant System (2005)

One hundred and forty-seven adult recipients of the Nucleus 24 cochlear implant system, from 13 different European countries, were tested using neural response telemetry to measure the electrically evoked compound action potential (ECAP), according to a standardised postoperative measurement procedure. Recordings were obtained in 96% of these subjects with this standardised procedure. The group results are presented in terms of peak amplitude and latency, slope of the amplitude growth function and ECAP threshold. The effects of aetiological factors and the duration of deafness on the ECAP were also studied. While large intersubject variability and intrasubject variability (across electrodes) were found, results fell within a consistent pattern and a normative range of peak amplitudes and latencies was established. The aetiological factors had little effect on the ECAP characteristics. However, age affected ECAP amplitude and slope of the amplitude growth function significantly; i.e., the amplitude is higher in the lowest age category (15-30 years). Principal component analysis of the ECAP thresholds shows that the thresholds across 5 electrodes can be described by two factors accounting for 92% of the total variance. The two factors represent the overall level of the threshold profiles ('shift') and their slopes across the electrode array ('tilt'). Correlation between these two factors and the same factors describing the T- and C-levels appeared to be moderate, in the range of 0.5-0.6.
Design and analysis of a hybrid control scheme for sandwich nonsmooth nonlinear systems (2002)

This paper addresses an open control problem: the control of sandwich non-smooth nonlinear systems. Of interest are sandwiched non-smooth nonlinearities between linear dynamic blocks, as illustrated by a hydraulic valve system with a sandwiched dead-zone. A hybrid control scheme for the control of such sandwich systems is developed and presented in detail. The proposed control scheme employs an inner-loop discrete-time feedback design and an outer-loop continuous-time feedback design, combined with a nonlinearity inverse, to cancel the nonlinearity effect, for improving output tracking. The stability and tracking performance of the closed-loop control system are analyzed. Simulations are used to illustrate the effectiveness of the proposed hybrid control design.
Humidity-dependent phase state of SOA particles from biogenic and anthropogenic precursors (2012)

Abstract. The physical phase state (solid, semi-solid, or liquid) of secondary organic aerosol (SOA) particles has important implications for a number of atmospheric processes. We report the phase state of SOA particles spanning a wide range of oxygen to carbon ratios (O / C), used here as a surrogate for SOA oxidation level, produced in a flow tube reactor by photo-oxidation of various atmospherically relevant surrogate anthropogenic and biogenic volatile organic compounds (VOCs). The phase state of laboratory-generated SOA was determined by the particle bounce behavior after inertial impaction on a polished steel substrate. The measured bounce fraction was evaluated as a function of relative humidity and SOA oxidation level (O / C) measured by an Aerodyne high resolution time of flight aerosol mass spectrometer (HR-ToF AMS). The main findings of the study are: (1) biogenic and anthropogenic SOA particles are found to be amorphous solid or semi-solid based on the measured bounced fraction (BF), which was typically higher than 0.6 on a 0 to 1 scale. A decrease in the BF is observed for most systems after the SOA is exposed to relative humidity of at least 80% RH, corresponding to a RH at impaction of 55%. (2) Long-chain alkanes have a low BF (indicating a "liquid-like", less viscous phase) particles at low oxidation levels (BF &lt; 0.2 ± 0.05 for O / C = 0.1). However, BF increases substantially upon increasing oxidation. (3) Increasing the concentration of sulphuric acid (H2SO4) in solid SOA particles (here tested for longifolene SOA) causes a decrease in BF levels. (4) In the majority of cases the bounce behavior of the various SOA systems did not show correlation with the particle O / C. Rather, the molar mass of the gas-phase VOC precursor showed a positive correlation with the resistance to the RH-induced phase change of the formed SOA particles.
A portable BCPL library (2021)

Too often, programs written in BCPL are difficult to port from one system to another, not because of the language, but because of differences between ‘standard’ libraries. Almost without exception, the definitions of these libraries are loose, woolly and inaccurate – the proposed BCPL standards document being a prime example. The author has developed and implemented a new BCPL library which is explicitly designed to aid the portability of programs between systems. In addition to being largely portable itself, it has two other features of interest: it uses an exception handling system instead of return codes, and it makes no distinction between system and user defined stream handlers. This paper defines the interface to the package.
Minimizing Global Interconnect in DSP Systems using Bypassing (2007)

There is a wide consensus that performance and power consumption of IC designs in deep submicron technologies is mainly dictated by interconnect requirements. Our goal is demonstrate how compilation and architectural techniques can be used to minimize and balance interconnect requirements. Specifically, we target the use of bypass units to reduce routing congestion and eliminate long interconnections while essentially preserving or even improving the throughput requirements. We formulate the bypassing problem, establish its complexity and develop an efficient integer-linear programming (ILP) formulation. In addition to satisfying user specified interconnect requirements, we simultaneously optimize the number of operations and, therefore runtime of the targeted application. The approach is prototyped and evaluated using a platform consisting of the Trimaran architecture and compilation tools and the CPLEX ILP solver.
Query strategies for priced information (extended abstract) (2000)

Article Query strategies for priced information (extended abstract) Share on Authors: Moses Charikar Computer Science Department, Stanford University, CA Computer Science Department, Stanford University, CAView Profile , Ronald Fagin IBM Almaden Reseach Center, 650 Harry Road, San Jose, CA IBM Almaden Reseach Center, 650 Harry Road, San Jose, CAView Profile , Venkatesan Guruswami Laboratory for Computer Science, MIT, Cambridge, MA Laboratory for Computer Science, MIT, Cambridge, MAView Profile , Jon Kleinberg Department of Computer Science, Cornell University, Ithaca, NY Department of Computer Science, Cornell University, Ithaca, NYView Profile , Prabhakar Raghavan IBM Almaden Reseach Center, 650 Harry Road, San Jose, CA IBM Almaden Reseach Center, 650 Harry Road, San Jose, CAView Profile , Amit Sahai Laboratory for Computer Science, MIT, Cambridge, MA Laboratory for Computer Science, MIT, Cambridge, MAView Profile Authors Info & Claims STOC '00: Proceedings of the thirty-second annual ACM symposium on Theory of computingMay 2000 Pages 582–591https://doi.org/10.1145/335305.335382Published:01 May 2000 11citation297DownloadsMetricsTotal Citations11Total Downloads297Last 12 Months2Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Reliability of the Prognos Electrodermal Device for Measurements of Electrical Skin Resistance at Acupuncture Points (2004)

Prognos performs accurately, against known resistors over the reported range of ESR. The reliability in the standard protocol (r = 0.758) is comparable to the reliability of 0.721 demonstrated under similar conditions by other investigators. Marking APs, and performing measurements in a rapid sequence, increases reliability of ESR measurements. Increased reliability in the second and third protocols is associated with decreased mean ESR values which may be related to increased accuracy of Prognos probe placement and/or inking the APs.
Impact hammer-based analysis of nonlinear effects in bolted lap joint (2016)

This work presents an experimental investigation into the dynamic behavior of a bolted joint beam configuration. The impact hammer is chosen as an alternative to classical harmonic excitation methods. The structural responses are explored for a range of the joint tightening toques and various levels of impulse hammer excitations. A symmetric beam assembly made of two nominally identical steel beams is studied. Symmetric modes are found to be sensitive to the test parameters. For given torque, impact-based varying joint loading conditions are used to induce the nonlinear joint effects. A linear data processing strategy is used to observe the nonlinear behavior indirectly. The dynamic joint behavior is described in the form of the modal frequency-damping ratio performance maps represented by the two-parametric approximating quadratic response surface models. This model maps the joint conditions on the corresponding dynamic characteristics of interest and it will serve as a basis for the parametric linear joint model development
The pain chronicles (2011)

The time has come," the Walrus said, "To talk of many things: Of shoes -and ships -
Tuning Material Properties of Oxides and Nitrides by Substrate Biasing during Plasma-Enhanced Atomic Layer Deposition on Planar and 3D Substrate Topographies (2018)

Oxide and nitride thin-films of Ti, Hf, and Si serve numerous applications owing to the diverse range of their material properties. It is therefore imperative to have proper control over these properties during materials processing. Ion-surface interactions during plasma processing techniques can influence the properties of a growing film. In this work, we investigated the effects of controlling ion characteristics (energy, dose) on the properties of the aforementioned materials during plasma-enhanced atomic layer deposition (PEALD) on planar and 3D substrate topographies. We used a 200 mm remote PEALD system equipped with substrate biasing to control the energy and dose of ions by varying the magnitude and duration of the applied bias, respectively, during plasma exposure. Implementing substrate biasing in these forms enhanced PEALD process capability by providing two additional parameters for tuning a wide range of material properties. Below the regimes of ion-induced degradation, enhancing ion energies with substrate biasing during PEALD increased the refractive index and mass density of TiO <sub>x</sub> and HfO <sub>x</sub> and enabled control over their crystalline properties. PEALD of these oxides with substrate biasing at 150 °C led to the formation of crystalline material at the low temperature, which would otherwise yield amorphous films for deposition without biasing. Enhanced ion energies drastically reduced the resistivity of conductive TiN <sub>x</sub> and HfN <sub>x</sub> films. Furthermore, biasing during PEALD enabled the residual stress of these materials to be altered from tensile to compressive. The properties of SiO <sub>x</sub> were slightly improved whereas those of SiN <sub>x</sub> were degraded as a function of substrate biasing. PEALD on 3D trench nanostructures with biasing induced differing film properties at different regions of the 3D substrate. On the basis of the results presented herein, prospects afforded by the implementation of this technique during PEALD, such as enabling new routes for topographically selective deposition on 3D substrates, are discussed.
Patient retention and costs associated with a pancreatic multidisciplinary clinic. (2012)

96 Background: Multidisciplinary clinics (MDC) are a burgeoning method of administering timely and comprehensive oncologic care. The continuity of care achievable with MDCs, in addition to their costs, are not well-described. We compared retention rates and charges for MDC patients to patients with individual referrals at the same academic center. Methods: The geographic origins of 482 MDC patients and 3,766 non-MDC patients, all referred for pancreatic cancer treatment between 2008-2010, were defined as “local,” “adjacent states,” and “non-adjacent states.” Proportions of patients in each group who presented initially and subsequently returned were compared using chi-squared tests. Multivariate adjustment was performed for disease stage and other clinical risk factors. Gross charges per patient were determined using billing data. Results: Overall, the MDC retained a higher percentage of patients for subsequent treatment than the non-MDC group (60.8% vs. 53.6%; p=0.003), as well as all three individual regions. Multivariate adjustment results are not yet available, but will be at the time of the meeting. Mean charges per patient were 11% higher for the non-MDC group. Conclusions: The MDC achieved higher patient retention, suggesting improved continuity of care. Total charges were higher for the non-MDC group, suggesting that MDCs may be more cost-effective. [Table: see text] [Table: see text]
Characterization of Polyisoprene-b-Poly(methyl methacrylate) Diblock Copolymer Micelles in Acetonitrile (1999)

In acetonitrile, polyisoprene-b-poly(methyl methacrylate) (PI−PMMA) diblock copolymers form starlike micelles with a dense core of the insoluble PI blocks and a soft solvent-swollen corona of the soluble PMMA blocks. Static and dynamic light scattering experiments in combination with viscosity measurements show that these micelles behave hydrodynamically as hard spheres. The block copolymers are labeled at the block junction, with a single fluorescent dye, either a donor chromophore (phenanthrene) or an acceptor chromophore (anthracene). These dyes are confined to the interface during self-assembly. Fluorescence energy-transfer experiments on molecularly mixed micelles of donor- and acceptor-labeled copolymers provide a core radius of 7.6 ± 0.8 nm and a number-average aggregation number ( ) of 98 ± 22 under the assumption that the energy transfer takes place on a surface of a sphere. Simulations in terms of a Helfand−Tagami junction distribution profile confirm that the core−corona interface of the PI−PMMA micelles is thin (ca. 0.9 nm) and that almost all of the energy transfer occurs within a narrow interfacial region. From the static light scattering measurements of the mixed micelles a weight-average aggregation number ( ) of 127 ± 6 is obtained. The ratio / = 1.3 agrees with size polydispersity of the micelles obtained from the analysis of dynamic light scattering data. The experimental corona thicknesses are in good agreement with those calculated from expressions describing starlike block copolymer micelles.
Targeted Covalent Inhibitors for the Treatment of Malaria? (2020)

Malaria is a vector-borne disease caused by protozoan parasites of the genus <i>Plasmodium</i>. According to the World Health Organization, it is one of the most serious infectious diseases threatening more than 3 billion people worldwide. In recent years, targeted covalent inhibitors (TCIs) have gained a lot of attention and several TCI-based drugs have been approved across different therapeutic areas. For malaria, surprisingly, this approach has not been explored in depth even though lot of advancements have been made in understanding the biology of the parasite. Herein, we present our views on exploring TCIs as a new class of antimalarial agents.
Flame retardancy of polylactide: an overview (2010)

The paper reviews the different methods for flame retarding polylactide (PLA). They are critically discussed based on the open and patent literature. No real specific methods have been developed for PLA but some approaches provide high performance and especially intumescence. The mechanisms of action remain similar to those observed in other polymers.
Robust and adaptive control of a beam deflector (1988)

A DC-motor driven beam-deflector is to be controlled such that the beam moves with constant velocity for 12 ms out of a 20-ms period before swinging back to the original position. One control system must serve any deflector without retuning. The problem is difficult because the dynamics vary from one deflector to another. It is found that a closed-loop system with poles in a Bessel filter configuration will satisfy the specifications. A straightforward pole-placement design is insufficiently robust. Redesigning it yields greater, but still insufficient, robustness against the known extent of plant parameter variation. The problem is solved by adding an adaptive control loop.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
A novel process concept for the three step Boscalid® synthesis (2016)

A three phase microemulsion system was applied for a more sustainable synthesis of the fungicide Boscalid®.
Integrated Signal Processing and Signal Understanding (1991)

Despite intensive clinical and research efforts during recent decades, the prognosis of patients with stage IV melanoma still remains poor. Finding effective adjuvant treatment for patients with a high risk of relapse and metastasis is one of the most urgent needs in clinical research. Systemic adjuvant chemotherapy administered in several clinical trials offered no benefit in terms of improved relapse-free or overall survival. Interferon alpha-2a and -2b treatment was the first treatment in the adjuvant setting which has shown a treatment benefit and received approval in Germany. Today clinical research focuses on improved treatment schedules with conventional interferon compared to pegylated interferon as well as on new compounds such as CTLA4 inhibitors like ipilimumab or a vaccination against the MAGE-A3 peptide.
Thermal issues in a backwafer contacted silicon-on-glass integrated bipolar process (2002)

The electro-thermal behavior of NPNs fabricated in a backwafer contacted silicon-on-glass integrated bipolar process has been investigated experimentally and the results are supported by 2D MEDICI simulations including the lattice heating equation. The devices are fabricated in silicon islands, the smallest of which is 23/spl times/10/spl times/0.94 /spl mu/m/sup 3/. This device exhibits thermal runaway in the Gummel plot at a very low power level of 1.5 mW, where V/sub BE/=0.8 V for V/sub CB/=0 V. A new emitter-current-controlled measurement technique is introduced, whereby the point of thermal runaway can be identified as a flyback point in the I/sub C/-V/sub BE/ characteristics. Calculations are performed to estimate the temperature rise at this point along with the thermal resistance of the device. For the smallest device, the thermal resistance is found to be very high, about 15000 K/W. The thermal stability can be improved by reducing the thermal resistance, which is achieved here by either increasing the size of the silicon island or, more effectively, by adding large areas of metal directly to the device contacts. In all devices studied, the temperature rise at the flyback point was found to be about 25/spl deg/C and not very dependent on the thermal resistance. The collector contact is fabricated on the backwafer directly under the emitter and has a very low series resistance. Increasing this series resistance to values comparable to bulk silicon devices is also shown to reduce the susceptibility to thermal runaway.