gebhart/patrepeval huggingface dataset:
Longitudinal Mode-partition Noise In Diode Lasers (1997)

Constant-current-driven diode lasers at high pumping often show noise (intensity noise) larger than the shot-noise contrary to the squeezing predicted by theory. Some researchers have speculated that the excess noise comes from the mode-partition noise that results from division of saturated gain into several different longitudinal modes.1 We, for the first time, we believe, have measured the mode-partition noise of the free-running as well as the injection-locked and external-cavity diode lasers using an interferometer. By comparing the mode-partition noise and the total noise in the three cases, we were able to demonstrate the relation between the two.
Studies on the Fluorescence of the Human Vitamin A-transporting Plasma Protein Complex and Its Individual Components (1971)

Abstract The fluorescence properties of the human prealbumin-retinol-binding protein (RBP) complex and of its individual components are described. At neutral pH, RBP and the protein complex have two fluorescence bands: one at 335 nm and the other, associated with the retinol, at 470 nm. Prealbumin has only a fluorescence at 335 nm (quantum yield 0.11). The quantum yield of retinol increased by 50% and the emission spectrum was blue shifted on RBP forming a complex with prealbumin. RBP, at low ionic strength where the binding of RBP and prealbumin is abolished, exhibited a decrease in the quantum yield of retinol. With the protein fluorescence of RBP and the fluorescence of its cofactor, it was also possible to show the occurrence of transfer of excitation energy from the protein moiety to the retinol (efficiency of transfer: 60%). Studies on the accessibility of the aqueous medium (or protons) to the retinol site revealed that on complex formation between RBP and prealbumin most of the retinol-solvent interactions are abolished, suggesting that one of the functions of prealbumin is to stabilize the retinol-binding site of RBP. The estimated apparent association constant is 2 x 107 m-1 for the interaction of retinol-containing RBP and prealbumin. The binding constant of prealbumin and vitamin A-free RBP was also determined. A similar value was found and it is thus concluded that retinol has no major influence on the tertiary structure of RBP.
Assessment of cognitive dysfunction in kidney disease (2010)

Background: Cognitive dysfunction, include reducedmental alertness, intellectual impairment, decreasedattention and concentration, memory deficits anddiminished perceptual-motor coordination. Both CKDand chronic dialysis patients are thought to be associatedwith cognitive impairment. Cognitive impairment maydecrease an individual's quality of life, increase resourceutilization and result in suboptimal medical care.Neurophysiologic tests using imaging techniques areused to evaluate structural and functional abnormalities.Neuropsychological testing uses validated questions andscreening tests to evaluate cognition.Setting and participants: This study was carried out on120 patients with different stages of CKD fromnephrology outpatient clinic and hemodialysis unit inAin Shams University Hospitals. Group I: 50 CKDpatients, stage ? and stage IV. Group II: 50 ESRDpatients on regular hemodialysis with K t/v &gt; 1.1. GroupIII: 20 acute kidney injury patients, followed up till theirrenal functions stabilized. Group ?V: 20 healthy subjectsmatched with patients. All patients underwent laboratoryinvestigations and psychometric tests which include trialmaking test part B, digit span test, digit symbol test,mini-mental state examination.Results: There were highly significant differences ofmean values of cognitive function tests between (groupsI,II and III as compared with group IV (control group),stage III CKD and stage IV CKD, CKD andhemodialysis patients, AKI patient at the insult and afterrecovery) and finally between hemoglobin and cognitivefunction tests score.Conclusions: There were significant differences of cognitive function tests results between CKD, III,IV,V, AKI patients as compared with healthy group, suggesting that kidney disease affects cognitive performance, there were significant differences of cognitive function tests results between stage III CKD and stage IV CKD, suggesting that the degree of cognitive impairment is associated with the severity of CKD, also significant differences of cognitive function tests results between CKD and ESRD on hemodialysis, suggesting that dialysis improves cognitive performance. Our results showed significant differences of cognitive function tests results between AKI patients at the insult and after recovery, suggesting that AKI also impair cognitive function. Finally cognitive performance is affected by hemoglobin level in CKD stage III, IV, V on hemodialysis and AKI patients, suggesting that treatment of anemia in AKI, CKD and ESRD patients improve cognitive performance.
Regional Variation of Causative ALS Genes (P2.069) (2014)

OBJECTIVE: To determine the frequency of C9ORF72 and other repeats expansion mutations in Utah’s multidisciplinary amyotrophic lateral sclerosis (ALS). BACKGROUND:C9ORF72 and ATXN2 are known associated ALS genes. C9ORF72 is the most common known genetic cause of ALS, with wide regional variation. C9ORF72 expansions of >30 repeats are causative for ALS, with about 90% penetrance by age 80. The severity of the disease does not correspond to length. Intermediate expansions of >15<30 are rarely reported and have unknown significance. ATXN2 intermediate length repeats (27-32) are associated with an increased risk for ALS and Parkinson’s disease. An estimated 2% of ALS cases in the US are reported to be related to an intermediate expansion. The purpose of the study is to analyze the incidence risk found in our regional clinic. DESIGN/METHODS: Consecutively collected DNA samples of ALS patients from University of Utah’s multidisciplinary ALS clinic were screened for 17 different repeat expansion mutations, using PCR. RESULTS: We collected a total of 96 ALS patient samples, eight from patients with a self reported history of familial ALS (fALS) and 86 from sporadic ALS (sALS) patients. We identified one sALS patient with an expanded pathological length repeat of C9ORF72 (>30) and no fLAS patients with a pathological repeat. Furthermore, seven ALS patients with intermediate (15-30) length repeats were identified. Three patients with intermediate length repeats had fALS, all others were sALS. Four ALS patients with an ATXN2 intermediate length repeat (27-32) were identified, one had fALS. We identified one sALS patient with a pathological repeat length of ATXN3, additional this patient also had an intermediate length repeat of C9ORF72. CONCLUSIONS: Genotypic analysis of consecutively collected DNA samples indicates increased unusual and rare ATXN2 and ATXN3 mutations. Additionally we report low regional frequency of C9ORF72 expansions, both in fALS and sALS. Most surprisingly we identified a very high percentage of intermediate length C9ORF72 expansions of unknown significance. Study Supported by: none
Tbps/mm bandwidth for chip-to-chip communication using fine pitch damascene RDL (2020)

Heterogeneous integration is a cost-effective solution to increase the performance of SoCs by taking advantage of the most appropriate process technology for each functional block that makes up a system. However, to operate efficiently, high bandwidth interconnects are required, and RDL comes as a cost-effective solution. This work shows that this technology can be used to design an interconnect capable of achieving bandwidth densities up to 1Tbps/mm. Moreover, this study shows that the performance of interconnects can be further improved by scaling the microbump pitches and developping new polymers.
System scenario framework evaluation on EFM32 using the H264/AVC encoder control structure (2015)

Hand held battery powered devices are becoming increasingly complex, with embedded applications that regularly demonstrate very dynamic behavior and requiring advanced functionality. To avoid prohibitively high power consumption, novel techniques are needed to handle the increased dynamicity and complexity, e.g., through use of system scenario based design. In this paper a framework for system scenario resource management is presented and evaluated with the H264/AVC encoder control structure on an EFM32 microcontroller. By using DFS as a system knob, we obtain significant power reductions for different system scenarios occurring dynamically while the application is running. The framework overhead is negligible.
On the physical and stochastic representation of an indicator dilution curve as a gamma variate (2008)

The analysis of intravascular indicator dynamics is important for cardiovascular diagnostics as well as for the assessment of tissue perfusion, aimed at the detection of ischemic regions or cancer hypervascularization. To this end, indicator dilution curves are measured after the intravenous injection of an indicator bolus and fitted by parametric models for the estimation of the hemodynamic parameters of interest. Based on heuristic reasoning, the dilution process is often modeled by a gamma variate. In this paper, we provide both a physical and stochastic interpretation of the gamma variate model. The accuracy of the model is compared with the local density random walk model, a known model based on physics principles. Dilution curves were measured by contrast ultrasonography both in vitro and in vivo (20 patients). Blood volume measurements were used to test the accuracy and clinical relevance of the estimated parameters. Both models provided accurate curve fits and volume estimates. In conclusion, the proposed interpretations of the gamma variate model describe physics aspects of the dilution process and lead to a better understanding of the observed parameters, increasing the value and credibility of the model, and possibly expanding its diagnostic applications.
Distribution of Heat-Transfer Coefficients from Small Surfaces Cooled with Submerged Jets of Fluorocarbon Liquid Determined with Inverse-Problem Analysis of Heat Conduction. (1995)

The method of inverse-problem analysis was used to determine the distribution of heat-transfer coefficients of a silicon heater cooled with submerged jets of fluorocarbon liquid. The silicon heater was made specifically to investigate high-performance cooling systems of electronic devices. The heater is constructed of many cells which can independently generate heat and measure the temperature on one side of the heater, and it is colled from the other side of the heater. Inverse-problem analysis was used to correct for heat conduction in the heater and to determine the distribution of heat transfer coefficients on the cooling surface. The heat-transfer coefficients were also measured by independent techniques to confirm the values determined with the inverse-problem analysis. One of these independent techniques was to control the heater power to produce a uniform temperature. Another technique was to use a SUS film heater. The distribution of heat transfer coefficients determined with these three techniques were in reasonable agreement.
Mobility and Capacity Offload for 3G UMTS Femtocells (2009)

Femtocells are low-power cellular base stations that are typically deployed indoors in residential, enterprise or hotspots settings. Femtocell deployments provide excellent user experience through better coverage for voice and very high data throughputs. In this paper, we focus on 3G UMTS femtocells and analyze the impact of femtocells on idle-mode mobility and UE battery life. Detailed dynamic simulations are presented to quantify the impact of femtocells on the number of cell searches, cell reselections and location area updates for both femtocell users and macro users. It is shown that femtocells reduce the number of intra-frequency and inter-frequency searches for femtocell users while increasing the number of searches for macro users. In addition, methods for facilitating capacity offload to femtocells are presented. In particular, cell reselection parameter optimization, use of beacons and enhancements of UE search algorithms are described as possible methods for facilitating capacity offload to femtocells. The tradeoffs between capacity offload and UE battery life are also evaluated.
Metalenses: Advances and Applications (2018)

Abstract Metasurfaces, the 2D counterpart of artificial metamaterials, have attracted much attention because of their exceptional ability to manipulate the electromagnetic wave such as amplitude, phase, polarization, propagation direction, and so on. Different from conventional lenses, metalenses based on the metasurface optics are truly flat and compact and exhibit superior performance. In this report, recent progress in the development of metalenses is explored. First, the working principle and characteristics of metalenses are discussed. Then, it is described how the dispersion aberration in metalenses can be eliminated to make them suitable for being employed in a range of applications that are difficult or impossible for traditional lenses. In addition, various metalens‐based applications are introduced, including imaging, high spectral resolution spectroscopy, and multiplex color routing. Furthermore, a survey of reconfigurable and tunable metalenses is conducted. Finally, the report concludes by addressing future prospects of metalenses.
Conditioning effects on thermal and dynamic mechanical properties of injection moulded glass fibre reinforced polyamide 6,6 composites (2011)

Polymer composites of polyamide 6,6 reinforced with short glass fiber were prepared by injection molding, conditioned under dry, 50% relative humidity (RH) and wet. Molded specimens were analyzed by thermogravimetric analyzer (TGA), differential scanning calorimetry (DSC) and dynamic mechanical analysis (DMA). TGA results revealed that glass fiber loading in PA 6,6 improve the thermal stability of the composites by an increase in Tonset and T50% as well as DTp values. DSC analysis revealed that the incorporation of glass fiber and moisture into the PA 6,6 matrix resulted in a remarkable decrease in the degree of crystallinity. However, the melting and crystallization temperatures of the composites are not significantly altered. DMA results revealed the glass transition temperatures are sensitive to moisture absorption and their values move to a lower temperature upon exposure to moisture.
Federated learning and privacy (2022)

Building privacy-preserving systems for machine learning and data science on decentralized data.
Correction to Discovery of Small-Molecule Inhibitors Selectively Targeting the DNA-Binding Domain of the Human Androgen Receptor (2017)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Discovery of Small-Molecule Inhibitors Selectively Targeting the DNA-Binding Domain of the Human Androgen ReceptorHuifang Li, Fuqiang Ban, Kush Dalal, Eric Leblanc, Kate Frewin, Dennis Ma, Hans Adomat, Paul S. Rennie, and Artem Cherkasov*Cite this: J. Med. Chem. 2017, 60, 3, 1225Publication Date (Web):January 24, 2017Publication History Published online24 January 2017Published inissue 9 February 2017https://pubs.acs.org/doi/10.1021/acs.jmedchem.7b00005https://doi.org/10.1021/acs.jmedchem.7b00005correctionACS PublicationsCopyright © 2017 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views1606Altmetric-Citations5LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (828 KB) Get e-Alertsclose Get e-Alerts
Weak consistency group communication for wide-area systems (2003)

Replicated services can be implemented as process groups. Member processes use group communication protocols to communicate amongst themselves and group membership protocols to determine what processes are in the group. These protocols can provide various levels of consistency between members. The author investigates weak consistency protocols that guarantee that messages are delivered to all members, but do not guarantee when. He reports on a new family of communication protocols, an associated group membership mechanism, and current progress in evaluating their efficiency and utility for real applications.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Gender Differences in Case Volume Among Ophthalmology Residents (2019)

Female residents performed 7.8 to 22.2 fewer cataract operations and 36.0 to 80.2 fewer total procedures compared with their male counterparts from 2005 to 2017, a finding that warrants further exploration to ensure that residents have equivalent surgical training experiences during residency regardless of gender. However, this study included a limited number of programs (24 of 119 [20.2%]). Future research including all ophthalmology residency programs may minimize the selection bias issues present in this study.
Chronic Subdural Hematoma (1993)

The management of chronic subdural hematoma in the adult patient is approached with a variety of different surgical techniques. The trend in recent years has been toward treatment with burr holes or twist-drill holes rather than craniotomy. The rationale for this has been based on the assumption that burr holes and twist-drill holes offer equivalent efficacy and lower morbidity and mortality. This viewpoint is not, however, universally accepted, and many surgeons feel that craniotomy is superior to a burr hole for the management of this condition. In a review of 92 patients presenting over a 3-year period with 112 chronic subdural hematomas, 49 underwent craniotomy and 43 underwent burr-hole treatment. The recurrence of hematomas, requiring another operation, occurred in 8.6%; operative mortality was 2.2% at hospital discharge and 4.4% at follow-up. No patient died as a consequence of the operative procedure. There was no significant difference in the incidence of postoperative complications, hematoma recurrence, or operative mortality among the different surgical groups. Previous reports concerning the superiority of burr holes over craniotomy are not substantiated by this review. Although the issue concerning optimal therapy has not been resolved by this review, at this time, craniotomy remains a valid and safe technique for the management of patients with chronic subdural hematoma.
An experimental study of prehension parameters during manipulation task (2006)

info:eu-repo/semantics/published
An exactly soluble model for the quantum defect formula (1981)

It is shown that the Schrödinger equation for a model potential consisting of a zero range square well attached to a coulomb tail can be solved exactly. The eigenvalues are found to agree with the quantum defect formula.
STUDY ON THE CORRELATION OF OVERWEIGHT AND OBESITY WITH HYPERTRIGLYCERIDAEMIA IN GANZHOU CITY AREA (2012)

<h3>Objectives</h3> To comprehend the current distribution of overweight and obesity in Ganzhou city residents, and to investigate the association between overweight, obesity and hypertriglyceridaemia. <h3>Methods</h3> 3000 residents from May to September 2011 in hospital for health examination were human subjects, and collected the data of height, body weight to account body mass index (BMI), and triglyceride concentration to do statistical analyses. <h3>Results</h3> The prevalence of overweight and obesity people were 29.6% and 5.6%, and all the prevalence of overweight and obesity, male were 38.0% higher than female 33.1%, the difference was not statistically significant (p&gt;0.05). The prevalence of hypertriglyceridemia in GanZhou residents were 34.07%, male was 39.8%, female was 29.9%, and also male higher than female, there was no significant difference between the two groups (p&gt;0.05). The overweight and obesity had different conditions in hypertriglyceridemia group and normal group, and there were significant differences, had statistics significance (p&lt;0.001). The obesity group had the highest triglyceride concentration, and the overweight group higher than the normal group. <h3>Conclusions</h3> The prevalence of overweight and obesity are very high in the Ganzhou city residents, and overweight and obesity were the important risk factors for hypertriglyceridaemia. To prevent overweight and obesity could reduce the incidence rate of hypertriglyceridaemia.
Subwavelength Multilayer Dielectrics: Ultrasensitive Transmission and Breakdown of Effective-Medium Theory (2014)

We show that a purely dielectric structure made of alternating layers of deep subwavelength thicknesses exhibits novel transmission effects which completely contradict conventional effective medium theories exactly in the regime in which those theories are commonly used. We study waves incident at the vicinity of the effective medium's critical angle for total internal reflection and show that the transmission through the multilayer structure depends strongly on nanoscale variations even at layer thicknesses smaller than λ/50. In such deep subwavelength structures, we demonstrate dramatic changes in the transmission for variations in properties such as periodicity, order of the layers, and their parity. In addition to its conceptual importance, such sensitivity has important potential applications in sensing and switching.
Genome-Wide Association Study of Genetic Predictors of Overall Survival for Non–Small Cell Lung Cancer in Never Smokers (2013)

To identify the genetic factors that influence overall survival in never smokers who have non-small cell lung carcinoma (NSCLC), we conducted a consistency meta-analysis study using genome-wide association approaches for overall survival in 327 never smoker patients with NSCLC from The University of Texas MD Anderson Cancer Center (Houston, TX) and 293 cases from the Mayo Clinic (Rochester, MN). We then conducted a two-pronged validation of the top 25 variants that included additional validation in 1,256 patients with NSCLC from Taiwan and assessment of expression quantitative trait loci (eQTL) and differential expression of genes surrounding the top loci in 70 tumors and matched normal tissues. A total of 94 loci were significant for overall survival in both MD Anderson and Mayo studies in the consistency meta-analysis phase, with the top 25 variants reaching a P value of 10(-6). Two variants of these 25 were also significant in the Taiwanese population: rs6901416 [HR, 1.44; 95% confidence interval (CI), 1.01-2.06] and rs10766739 (HR, 1.23; 95%CI, 1.00-1.51). These loci resulted in a reduction of median survival time of at least eight and five months in three populations, respectively. An additional six variants (rs4237904, rs7976914, rs4970833, rs954785, rs485411, and rs10906104) were validated through eQTL analysis that identified significant correlations with expression levels of six genes (LEMD3, TMBIM, ATXN7L2, SHE, ITIH2, and NUDT5, respectively) in normal lung tissue. These genes were also significantly differentially expressed between the tumor and normal lung tissue. These findings identify several novel, candidate prognostic markers for NSCLC in never smokers, with eQTL analysis suggesting a potential biologic mechanism for a subset of these observed associations.