gebhart/patrepeval huggingface dataset:
<p>Complications Following Self-Administration of Hyaluronic Acid Fillers: Literature Review</p> (2020)

The purpose of the present study is to review published literature regarding complications following self-administration of hyaluronic acid (HA) filler. The following keywords were searched in Pubmed and Cochrane database: filler AND self injection, hyaluronic acid AND self injection; filler AND self administration; hyaluronic acid AND self administration. Two authors performed title and abstract eligibility assessment independently. Gray literature and all articles cited in the included papers were also screened and their reference lists were examined to identify other potentially pertinent studies. Non-English papers were excluded. A total of 4 complications following self injection of HA were identified. Conversely, after performing a general search through the Google Internet search engine, with the item "self-injection of hyaluronic acid filler", there were 604,000 hits. The number of articles reporting complications after the self administration of HA is few. Despite that internet searches on the same topic shows that self-administration of HA fillers is a widely discussed phenomenon in several on-line forums. The present review suggests that complications after self-injection of HA are an under-reported phenomenon.
Enhancing physical-layer security in wireless communications using signal space diversity (2016)

In this paper, we enhance the security of OFDM systems in frequency selective fading channels using signal space diversity. In rich multipath environments, spatially separated channels are independent to each other. Hence, by adapting the interleaving pattern to the channel of the legitimate user, more diversity gain is provided to the legitimate user compared to an eavesdropper. This ensures secrecy in a time division duplex system, where the eavesdropper has no information regarding the channel of the legitimate user. The scheme can also be used in the conventional frequency division duplex system, which is more challenging in terms of security aspects because of the channel state information leakage. We verify the gain of our scheme by showing the improvement in the bit error rate performance.
Photo-excited carrier relaxation dynamics in InN films (2009)

Photo-excited carrier relaxation dynamics in InN films were investigated using femtosecond transient measurements. We measured two samples with different background carrier densities, and discussed the influence of the carrier densities on the relaxation dynamics. We also found that the slow decay component disappears under the optimized condition because of the effects of equilibrium band filling and bandgap renormalization.
Coupled NaCl entry into Necturus gallbladder epithelial cells (1982)

NaCl entry into Necturus maculosus gallbladder epithelial cells was studied by determination of the rate of fluid movement into the cell when the Na+-K+-ATPase was inhibited by 10(-4) M ouabain in the serosal bathing solution. The cell swelling was due to continuing entrance of NaCl into the cell across the apical membrane, which increased the solute content of the cell; the resultant rise in cell osmolality induced water flow and cell swelling. The rate of swelling was 4.3% of the cell volume per minute, equivalent to a volume flow across the apical membrane of 1.44 x 10(-6) cm/s, similar in magnitude to the normal rate of fluid absorption by the gallbladder. We determined the mechanism of NaCl entry by varying the ionic composition of the mucosal bath; when most of the mucosal Na+ or Cl- was replaced, cell volume did not increase during pump inhibition. The rate of NaCl entry was a saturable function of Na+ or Cl- in the mucosal bathing solution with K1/2 values of 26.6 mM for Na+ and 19.5 mM for Cl-. The mode of NaCl entry was probably not the parallel operation of Na+-H+ and Cl(-)-HCO-3 exchangers because of the lack of effect of bicarbonate removal or of the inhibitors amiloride and 4-acetamido-4'-isothiocyanostilbene-2,2'-disulfonic acid. NaCl entry was reversibly inhibited by bumetanide in the mucosal bathing solution. Transepithelial NaCl and water absorption is the result of the coupled, carrier-mediated movement of NaCl into the cell across the apical membrane and the active extrusion of Na+ by the Na+-K+-ATPase in the basolateral membrane.
Chapter 17. Glycolipid-based nanosystems for the delivery of drugs, genes and vaccine adjuvant applications (2014)

International audience
LLDPE modified by ultraviolet irradiation and toughening of PA66 (2006)

Some oxygen containing groups such as C—O,CO and —OH were introduced onto the molecular chains of linear low-density polyethylene(LLDPE) through ultraviolet irradiation in air without other additives and chemical pollution.These groups contents increase with the ultraviolet irradiation time.After the ultraviolet irradiation,the crystal shape and distance of the crystal plane of LLDPE remain unchanged.However,the melting temperature and crystallinity decrease.Compared with those of LLDPE/nylon66(PA66) composites,the dispersion of irradiated LLDPE in irradiated LLDPE/PA66 composites and the compatibility between irradiated LLDPE and PA66 and interfacial interaction are improved obviously.The mechanical properties of irradiated LLDPE/PA66 composites initially increase and then decrease with increasing the irradiation time.Their maximums are obtained when the irradiation time was 24 h.The tensile strength,bending strength and notched impact strength of irradiated LLDPE for 24h/PA66 composites increase by about 20%,13% and 330% compared with those of LLDPE/PA66 composites;the irradiated LLDPE shows higher toughening effect.
Pattern Formation in Binary Colloidal Assemblies: Hidden Symmetries in a Kaleidoscope of Structures (2018)

In this study, we present a detailed investigation of the morphology of binary colloidal structures formed by self-assembly at air/water interface of particles of two different sizes, with a size ratio such that the larger particles do not retain a hexagonal arrangement in the binary assembly. While the structure and symmetry of binary mixtures in which such hexagonal order is preserved has been thoroughly scrutinized, binary colloids in the regime of nonpreservation of the hexagonal order have not been examined with the same level of detail due also to the difficulty in finding analysis tools suitable to recognize hidden symmetries in seemingly amorphous and disordered arrangements. For this purpose, we resorted to a combination of different analysis tools based on computational geometry and computational topology to get a comprehensive picture of the morphology of the assemblies. By carrying out an extensive investigation of binary assemblies in this regime with variable concentration of smaller particles with respect to larger particles, we identify the main patterns that coexist in the apparently disordered assemblies and detect transitions in the symmetries upon increase in the number of small particles. As the concentration of small particles increases, large particle arrangements become more dilute and a transition from hexagonal to rhombic and square symmetries occurs, accompanied also by an increase in clusters of small particles; the relative weight of each specific symmetry can be controlled by varying the composition of the assemblies. The demonstration of the possibility to control the morphology of apparently disordered binary colloidal assemblies by varying experimental conditions and the definition of a route for the investigation of disordered assemblies are important for future studies of complex colloidal patterns to understand self-assembly mechanisms and to tailor the physical properties of colloidal assemblies.
1366: Correlation between Stone Formation and Weight Loss After Roux-en-Y Gastric Bypass (2007)

You have accessJournal of UrologyPodium 40, Tuesday, May 22, 2007, 10:00 am - 12:00 pm1 Apr 20071366: Correlation between Stone Formation and Weight Loss After Roux-en-Y Gastric Bypass Victor A. Leitao, Gevorg Mutafyan, George E. Haleblian, Marnie R. Robinson, Sean A. Pierre, Aurora Pryor, John P. Grant, and Glenn M. Preminger Victor A. LeitaoVictor A. Leitao More articles by this author , Gevorg MutafyanGevorg Mutafyan More articles by this author , George E. HaleblianGeorge E. Haleblian More articles by this author , Marnie R. RobinsonMarnie R. Robinson More articles by this author , Sean A. PierreSean A. Pierre More articles by this author , Aurora PryorAurora Pryor More articles by this author , John P. GrantJohn P. Grant More articles by this author , and Glenn M. PremingerGlenn M. Preminger More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)31580-5AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1366: Correlation between Stone Formation and Weight Loss After Roux-en-Y Gastric Bypass." The Journal of Urology, 177(4S), pp. 450–451 © 2016 by American Urological AssociationFiguresReferencesRelatedDetailsCited ByNatarajan V, Master V and Ogan K (2018) Effects of Obesity and Weight Loss in Patients With Nononcological Urological DiseaseJournal of Urology, VOL. 181, NO. 6, (2424-2429), Online publication date: 1-Jun-2009. Volume 177Issue 4SApril 2007Page: 450-451 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Victor A. Leitao More articles by this author Gevorg Mutafyan More articles by this author George E. Haleblian More articles by this author Marnie R. Robinson More articles by this author Sean A. Pierre More articles by this author Aurora Pryor More articles by this author John P. Grant More articles by this author Glenn M. Preminger More articles by this author Expand All Advertisement Loading ...
Time-Domain Modeling of a Phase-Domain All-Digital Phase-Locked Loop for RF Applications (2007)

A new all-digital phase-locked loop (ADPLL) for RF wireless applications has recently been proposed and commercially demonstrated. It replaces conventional phase/frequency detector and charge pump with a time-to-digital converter (TDC). Analog frequency tuning of a VCO is replaced with an all-digital tuning of a digitally-controlled oscillator (DCO). In this paper, we present novel time-domain modeling and simulation techniques of the ADPLL phase detection mechanism as well as the frequency perturbation and phase noise characteristics of the DCO. The modeling principles are demonstrated for a GSM standard and validated through experimental results.
Sub-sampling of RF and THz waves using LT-GaAs Fabry-P é rot Cavity photoconductors under 1550 nm light excitation (2018)

We study low-temperature-grown, GaAs-based Fabry-Pérot cavity photoconductors, designed for RF and THz optoelectronics applications using 1550 nm lasers. We present here the sub-sampling of continuous waves at frequencies up to 300 GHz with a SNR of 70 dB.
Supplementary Data from Nonclinical Characterization of Bexmarilimab, a Clever-1–Targeting Antibody for Supporting Immune Defense Against Cancers (2023)

Supplementary Data from Nonclinical Characterization of Bexmarilimab, a Clever-1–Targeting Antibody for Supporting Immune Defense Against Cancers
High-resolution CT reconstruction from Zoom-In Partial Scans (ZIPS) with simultaneous estimation of inter-scan ROI motion (2022)

The Zoom-In Partial Scans (ZIPS) method is a recently introduced high-resolution CT technique that utilizes the high geometric magnification in off-center regions in the CT scanner’s field-of-view to boost the intrinsic spatial resolution of existing clinical multi-slice CT. ZIPS performs two off-center partial high-resolution scans of a region of interest (ROI), then an image reconstruction algorithm merges the partial scan data to produce a final high-resolution reconstructed image. In this study, we illustrate the feasibility of ZIPS image reconstruction with simultaneous estimation of inter-scan rigid ROI motion between the two partial scans. A total-variation and an entropy-based image alignment loss function was introduced for registration of the ROI between the two partial scans. Optional denoising filters were also introduced to stabilize the image alignment loss function. The feasibility of the ZIPS reconstruction framework is evaluated in a Catsim simulation environment. Results show that the proposed algorithmic compensation of ROI motion produced images visually indistinguishable from the images reconstructed with the ground truth positions of the ROI. The residual errors of the estimated ROI positions were no greater than 0.12 mm in x- and y- translation and 0.26 degree in rotation. Up to twofold improvement in the modulation transfer function (MTF) was achieved by ZIPS CT relative to a conventional centered scan.
Advanced non-native English on a continuum of Englishes : Charting new data sources (2015)

This presentation discusses research in which the objective is to find new empirical and theoretical ways of approaching the ongoing globalization of English. A particular angle is to test the usability of corpus-based diachronic methods for studying advanced non-native Englishes and to investigate present-day non-native use as one stage in the long continuum of Englishes. Such an approach is motivated by calls from the English as a lingua franca (ELF) domain to provide diachronically-informed evidence of English in multilingual settings (Seildhofer 2011) and by recent attempts in the study of indigenized World Englishes to take into account diachronic processes in shaping the outer circle Englishes (Noel, van Rooy & van der Auwera 2014). In particular, we investigate how ongoing grammatical variability, which is widely documented in many native varieties, is adapted in advanced non-native use. A key question is to investigate to what extent multilingual settings contribute to ongoing variability. The presentation discusses requirements for sources of material and evidence, and its starting point is the fact that the ELF research has so far focused on meaning making in interaction, which is also reflected in the scope of corpus resources. We zoom into ongoing corpus compilation work in which the aim is to collect a representative multi-genre sample of English texts in multilingual settings. The objective is that the sampling frame should enable diachronic and diatopic analyses of advanced nonnative use and make possible quantitative comparisons between our evidence and some of the existing English corpora, both native and non-native. The presentation discusses the diverse nature of our data and presents how we turn the data into evidence. We will introduce the set of grammatical structures, stemming from the corpus material, which have so far been investigated, and discuss a set of broader research questions to which this type of multi-genre corpus material of English texts in multilingual settings could shed more light.
The Functional Anaesthetic Discogram: Description of a Novel Diagnostic Technique and Report of 3 Cases (2008)

Level 4 - Case Series.
Faculty Opinions recommendation of IL-23 promotes tumour incidence and growth. (2006)

Chronic inflammation has long been associated with increased incidence of malignancy and similarities in the regulatory mechanisms have been suggested for more than a century. Infiltration of innate immune cells, elevated activities of matrix metalloproteases and increased angiogenesis and vasculature density are a few examples of the similarities between chronic and tumour-associated inflammation. Conversely, the elimination of early malignant lesions by immune surveillance, which relies on the cytotoxic activity of tumour-infiltrating T cells or intra-epithelial lymphocytes, is thought to be rate-limiting for the risk to develop cancer. Here we show a molecular connection between the rise in tumour-associated inflammation and a lack of tumour immune surveillance. Expression of the heterodimeric cytokine interleukin (IL)-23, but not of its close relative IL-12, is increased in human tumours. Expression of these cytokines antagonistically regulates local inflammatory responses in the tumour microenvironment and infiltration of intra-epithelial lymphocytes. Whereas IL-12 promotes infiltration of cytotoxic T cells, IL-23 promotes inflammatory responses such as upregulation of the matrix metalloprotease MMP9, and increases angiogenesis but reduces CD8 T-cell infiltration. Genetic deletion or antibody-mediated elimination of IL-23 leads to increased infiltration of cytotoxic T cells into the transformed tissue, rendering a protective effect against chemically induced carcinogenesis. Finally, transplanted tumours are growth-restricted in hosts depleted for IL-23 or in IL-23-receptor-deficient mice. Although many strategies for immune therapy of cancer attempt to stimulate an immune response against solid tumours, infiltration of effector cells into the tumour tissue often appears to be a critical hurdle. We show that IL-23 is an important molecular link between tumour-promoting pro-inflammatory processes and the failure of the adaptive immune surveillance to infiltrate tumours. PMID: 16688182
New conducting polymer film: poly(2,5-thienylenevinylene) prepared via a soluble precursor polymer (1987)

S. Yamada, S. Tokito, T. Tsutsui and S. Saito, J. Chem. Soc., Chem. Commun., 1987, 1448 DOI: 10.1039/C39870001448
Controlled delivery of antiangiogenic drug to human eye tissue using a MEMS device (2013)

We demonstrate an implantable MEMS drug delivery device to conduct controlled and on-demand, <i>ex vivo</i> drug transport to human eye tissue. Remotely operated drug delivery to human post-mortem eyes was performed via a MEMS device. The developed curved packaging cover conforms to the eyeball thereby preventing the eye tissue from contacting the actuating membrane. By pulsed operation of the device, using an externally applied magnetic field, the drug released from the device accumulates in a cavity adjacent to the tissue. As such, docetaxel (DTX), an antiangiogenic drug, diffuses through the eye tissue, from sclera and choroid to retina. DTX uptake by sclera and choroid were measured to be 1.93±0.66 and 7.24±0.37 μg/g tissue, respectively, after two hours in pulsed operation mode (10 s on/off cycles) at 23°C. During this period, a total amount of 192 ng DTX diffused into the exposed tissue. This MEMS device shows great potential for the treatment of ocular posterior segment diseases such as diabetic retinopathy by introducing a novel way of drug administration to the eye.
Cardiovascular Responses of Cows Given Electrical Current During Milking (1986)

Six Holstein cows in late lactation were used to determine effects of 4-mA square wave alternating current on mammary gland blood flow rate, heart rate, and blood pressure. Current to the lumbar-sacral region of the cows' back was applied 10 s prior to udder massage and throughout milking. Heart rate was measured from systolic pulses (beats/min) off strip chart recordings. Blood pressure determinations were made from carotid arterial cannulae. A single rise in blood flow rate occurred during milkings without current. Mammary blood flow increased (30% with respect to rest) without 40 s of milking. Heart rate and blood pressure did not change significantly. An abrupt increase in mammary blood flow rate, heart rate, and blood pressure was seen immediately upon current application prior to milking. Mammary blood flow rate increased 50%, heart rate 25 beats/min, and blood pressure 33 mm Hg. The response latency was approximately 60 s. A second rise in mammary blood flow (31%) was milking induced, occurring within 42 s of milking machine attachment. Milk yield was not influenced by current. Our data suggest that 4-mA of alternating current, applied prior to and throughout milking, causes an immediate elevation in mammary blood flow rate, heart rate, and blood pressure of cows. Cardiovascular responses are short-lived. Current given throughout milking does not influence normal physiological changes in mammary blood flow during milking.
Vascular Endothelial Growth Factor-B Acts as a Coronary Growth Factor in Transgenic Rats Without Inducing Angiogenesis, Vascular Leak, or Inflammation (2010)

VEGF-B appears to be a coronary growth factor in rats but not in mice. The signals for the VEGF-B-induced cardiac hypertrophy are mediated at least in part via the endothelium. Because cardiomyocyte damage in myocardial ischemia begins in the subendocardial myocardium, the VEGF-B-induced increased arterial supply to this area could have therapeutic potential in ischemic heart disease.
Thin film HTc SQUID construction and characterisation (1993)

The authors describe the process for manufacturing DC superconducting quantum interference devices (SQUIDs) using both step junctions and 45 degrees -rotated grain boundaries. An assessment of the noise performance and flux-to-voltage ratio for fourteen devices of various inductances, operating temperatures, and junction technologies is given. Systematic experiments on the technology steps required to construct fully integrated magnetometers and gradiometers are described. These include crossovers, superconducting interconnects, and film growth on undulating surfaces. For each of these, test structures have been constructed, and their properties have been measured. A simplified three-layer fully integrated DC SQUID magnetometer design is described. The authors highlight the need for improved reproducibility and demonstrate that, for a number of devices, there is no obvious relation between the temperature and the magnetic flux noise. The process for constructing interlayer superconducting contacts is shown to work, and the insulator has sufficient resistance for flux transformer applications.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Flexor Carpi Radialis Tendon Insertion Onto the Trapezial Ridge: An Anatomic Description (2022)

Understanding the complex anatomy of the hand and wrist facilitates surgical planning and intraoperative techniques. The FCR tendon insertion onto the trapezium is an important component of exposure for the volar approach to the distal radius and surgical management of thumb carpometacarpal joint arthritis.
Direct measurement of the quality factor in a two-dimensional photonic-crystal microcavity (2001)

A new microcavity design is proposed and structures are realized with a two-dimensional photonic-crystal slab. The cavity consists of seven defect holes that encompass a hexagon and is designed to reduce vertical light leakage. From a direct transmission measurement, a Q value of 816+/-30 is achieved at lambda =1.55 mum . This high- Q cavity will permit the realistic realization of spontaneous-emission modification and on-off optical switches.
Design of an astigmatism-correcting holographic collimator for gain-guided diode lasers (1991)

The astigmatism and asymmetrical divergence of gain-guided diode laser beams are major disadvantages in many uses. These characteristics are caused by asymmetry in the two traverse beam profiles: in the plane of the active junction confinement is effected by the electric current profile, whereas perpendicular to the junction the beam is trapped within the much narrower waveguide dimension. A holographic correcting and collimating element for such diodes is desirable for its low mass-production costs and small dimensions. Unfortunately, efficient holograms cannot be recorded directly with the infrared wavelengths of diode lasers. Large aberrations and reduced efficiencies are expected if the hologram would be recorded at shorter wavelengths. Previously 1 we presented a method for recording high-efficiency low-aberration collimators for spherical light sources with large recording/readout wavelength shifts. Here we generalize that method for astigmatic light sources. We record with nonspherical waves to compensate for wavelength shift aberrations and correct for the source’s astigmatism. Suitable wavefronts are derived from spherical holograms by a judicious choice of their readout and recording geometries.