gebhart/patrepeval huggingface dataset:
DC Bus Stabilization of Li-Ion Battery Based Energy Storage for a Hydrogen/Solar Power Plant for Autonomous Network Applications (2015)

This paper presents an energy management approach for a hybrid energy system comprised of a photovoltaic (PV) array and a polymer electrolyte membrane fuel cell (PEMFC). A single storage device, i.e., a Li-ion battery module, is used in the proposed structure. Linear proportional-integral (PI) and nonlinear flatness-based controllers for dc bus stabilization for power plants are compared. To verify the control approaches, a hardware system is realized with analog circuits for the PV, FC, and battery current control loops (inner controller loops) and with numerical calculation (dSPACE) for the external energy control loops. Experimental results with small-scale devices [namely, a PV array (800 W, 31 A), a PEMFC (1200 W, 46 A), and a Li-ion battery module (11.6 Ah, 24 V)] illustrate the excellent energy management scheme during load cycles, and the nonlinear differential flatness-based control was determined to provide improved dc bus regulation relative to a classical linear PI control method.
Gene trap analysis of germ cell signaling to Sertoli cells: NGF-TrkA mediated induction of Fra1 and Fos by post-meiotic germ cells (2001)

Analysis of complex signalisation networks involving distinct cell types is required to understand most developmental processes. Differentiation of male germ cells in adult mammals involves such a cross-talk between Sertoli cells, the somatic component which supports and controls germinal differentiation, and germ cells at their successive maturation stages. We developed a gene trapping strategy to identify genes, which, in Sertoli cells, are either up- or down-regulated by signals emitted by the germinal component. A library of approximately 2,000 clones was constituted from colonies independently selected from the Sertoli line 15P-1 by growth in drug-containing medium after random integration of a promoter-less (beta)geo transgene (neo(r)-lacZ fusion), which will be expressed as a fusion transcript from a 'trapped' cellular promoter, different in each clone. A first screen conducted on 700 events identified six clones in which beta-galactosidase activity was increased and one in which it was repressed upon addition of germ cells. The targeted loci were identified by cloning and sequencing the genomic region 5' of the insert. One of them was identified as the gene encoding Fra1, a component of the AP1 transcription regulatory complex. Accumulation of Fra1 mRNA was induced, both in 15P-1 and in freshly explanted Sertoli cells, by addition of either round spermatids or nerve growth factor (NGF). The effect of NGF was mediated by the TrkA receptor and the ERK1-ERK2 kinase kinase pathway. Fos and Fra1 transcription were induced within the first hour after addition of the neurotrophin, but, unlike what is observed after serum induction in the same cells, a second wave of transcription of Fra1, but not of Fos, started 16 hours later and peaked at higher levels at about 20 hours. These results suggest that AP1 activation may be an important relay in the Sertoli-germ cell cross-talk, and validate the gene trapping approach as a tool for the identification of target genes in cell culture systems.
Task-level robot learning on a complex task (1988)

Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Brain and Cognitive Sciences, 1989.
Creating alliesthesia in cool environments using personal comfort systems (2021)

Personal Comfort Systems (PCS) promise to reduce the energy needed to condition indoor environments, while also enhancing their occupants’ thermal pleasure. To explore these potentials in heating conditions, we compared the effectiveness of PCS heating various portions of the occupant against the normal Air Conditioning (AC) practice of warming the room volume. Twenty subjects experienced three modes of heating (AC only, AC together with PCS, and PCS only) at three initial room air temperatures (14, 16, and 18 °C) and were given some control options throughout the testing. Skin temperatures, thermal pleasantness, and thermal sensation votes were recorded during the exposures. The PCS heating was more effective than AC control at alleviating occupant discomfort. With PCS present, the three initial room temperatures produced equivalent positive perceptions of thermal pleasantness and sensation. Providing occupants with AC control did not influence this result. AC alone did not produce appreciable alliesthesia due to its slow rate of changing the room temperature. In contrast, PCS produced an immediate pleasantness experience with its faster-acting conductive and radiative heating spread non-uniformly across the body. Whole-body thermal pleasantness closely followed the pleasantness of local body parts experiencing thermal stimuli. These temporal and spatial characteristics give PCS a significant advantage in generating thermal pleasure over traditional AC systems.
2′-Modified Guanosine Analogs for the Treatment of HCV (2016)

Novel 2'-modified guanosine nucleosides were synthesized from inexpensive starting materials in 7-10 steps via hydroazidation or hydrocyanation reactions of the corresponding 2'-olefin. The antiviral effectiveness of the guanosine nucleosides was evaluated by converting them to the corresponding 5'-O-triphosphates (compounds 38-44) and testing their biochemical inhibitory activity against the wild-type NS5B polymerase.
Ad insertion in automatically composed documents (2012)

We consider the problem of automatically inserting advertisements (ads) into machine composed documents. We explicitly analyze the fundamental tradeoff between expected revenue due to ad insertion and the quality of the corresponding composed documents. We show that the optimal tradeoff a publisher can expect may be expressed as an efficient-frontier in the revenue-quality space. We develop algorithms to compose documents that lie on this optimal tradeoff frontier. These algorithms can automatically choose distributions of ad sizes and ad placement locations to optimize revenue for a given quality or optimize quality for given revenue. Such automation allows a market maker to accept highly personalized content from publishers who have no design or ad inventory management capability and distribute formatted documents to end users with aesthetic ad placement. The ad density/coverage may be controlled by the publisher or the end user on a per document basis by simply sliding along the tradeoff frontier. Business models where ad sales precede (ad-pull) or follow (ad-push) document composition are analyzed from a document engineering perspective.
Unconventional excitonic states with phonon sidebands in layered silicon diphosphide (2022)

Complex correlated states emerging from many-body interactions between quasiparticles (electrons, excitons and phonons) are at the core of condensed matter physics and material science. In low-dimensional materials, quantum confinement affects the electronic, and subsequently, optical properties for these correlated states. Here, by combining photoluminescence, optical reflection measurements and ab initio theoretical calculations, we demonstrate an unconventional excitonic state and its bound phonon sideband in layered silicon diphosphide (SiP<sub>2</sub>), where the bound electron-hole pair is composed of electrons confined within one-dimensional phosphorus-phosphorus chains and holes extended in two-dimensional SiP<sub>2</sub> layers. The excitonic state and emergent phonon sideband show linear dichroism and large energy redshifts with increasing temperature. Our ab initio many-body calculations confirm that the observed phonon sideband results from the correlated interaction between excitons and optical phonons. With these results, we propose layered SiP<sub>2</sub> as a platform for the study of excitonic physics and many-particle effects.
Single pulse proximal distance sensor with thermoacoustic transmitter (2009)

This paper reports on a small size ultrasonic proximal distance sensor. The size of fabricated proximal distance sensor is 10 mm times 8 mm times 1 mm, and it is small and thin enough to be put on a robot arm. Since a single pulse ultrasound generated by a thermoacoustic transmitter was used, the sensor can measure the proximal distance down to 3 mm without any interference from the transmitter. We measured the sensor's characteristics. By putting this sensor on the tip of the robot arm, we demonstrated the detection and evasive motion of an obstacle.
Combined in situXRD and in situXANES studies on the reduction behavior of a rhenium promoted cobaltcatalyst (2011)

A 10% Co-4% Re/(2% Zr/SiO(2)) catalyst was prepared by co-impregnation using a silica support modified by 2% Zr. The catalyst was characterized by temperature programmed reduction (TPR), in situ XRD and in situ XANES analysis where it was simultaneously exposed to H(2) using a temperature programmed ramp. The results showed the two step reduction of large crystalline Co(3)O(4) with CoO as an intermediate. TPR results showed that the reduction of highly dispersed Co(3)O(4) was facilitated by reduced rhenium by a H(2)-spillover mechanism. In situ XRD results showed the presence of both, Co-hcp and Co-fcc phases in the reduced catalyst at 400 °C. However, the Co-hcp phase was more abundant, which is thought to be the more active phase as compared to the Co-fcc phase for CO hydrogenation. CO hydrogenation at 270 °C and 5 bar pressure produces no detectable change in the phases during the time of experiment. In situ XANES results showed a decrease in the metallic cobalt in the presence of H(2)/CO, which can be attributed due to oxidation of the catalyst by reaction under these conditions.
Précipitation dans les structures (2013)

La conception optimale des composants introduit la nécessité de suivre les matériaux qui les composent tout au long de leur vie. Le présent travail illustre par une série d'exemples sur les alliages métalliques (aluminium, nickel, titane) le rôle joué par le vieillissement et la précipitation sur le comportement et la rupture, et comment ils doivent être pris en compte dans les chaînes de calcul.
Experimental demonstration of a broadband time-asymmetric waveguide architecture enabled by dynamically encircling an exceptional point in the optical domain (Conference Presentation) (2018)

We experimentally demonstrate a robust Si-photonic waveguide architecture that realizes dynamically encircling an exceptional point (EP) in the optical domain and broadband asymmetric modal transmission as an essential consequence. The structure consists of a pair of coupled channel waveguides and an adjacent slab-waveguide patch that enable precise lithographic controls on the phase velocities and radiation rates of the guided photonic modes. Complex modal index and inter-mode coupling constant profiles required for the encircling-an-EP parametric control are precisely coded in the geometry of those elements. The device created on this basis induces the symmetry-exchanging adiabatic state flip for one transmission direction and symmetry-preserving anti-adiabatic state-jump for the transmission in the opposite direction. In fabrication, we use a state-of-the-art electron-beam lithography for creating mm-long devices with nm-scale transversal precision. A comprehensive spectral measurement for the intensity and phase distributions of the transmitted optical states is obtained with a specially designed phase-sensitive infrared microscopy integrated with a tunable diode-laser system and spectrum analyzer. On this basis, we confirm in the experiment the highly asymmetric modal transmission persisting over a broad spectral band exceeding 100 nm in the telecommunications window around 1,550 nm. Hence, we establish a substantive experimental step toward broadband non-reciprocal photonic devices based on the unique non-Hermitian dynamics.
Observations on the scope of an intramolecular directed aldol condensation. A new synthesis of eight-membered rings (1983)

The TiCl4-catalysed intramolecular directed aldol condensation of silyl enol ethers and acetals can be used to make 6-, 7-, and 8-membered rings; a template effect of Ti is invoked to explain the formation of medium rings.
The nematode Caenorhabditis elegans as a tool to predict chemical activity on mammalian development and identify mechanisms influencing toxicological outcome (2016)

To determine whether a C. elegans bioassay could predict mammalian developmental activity, we selected diverse compounds known and known not to elicit such activity and measured their effect on C. elegans egg viability. 89% of compounds that reduced C. elegans egg viability also had mammalian developmental activity. Conversely only 25% of compounds found not to reduce egg viability in C. elegans were also inactive in mammals. We conclude that the C. elegans egg viability assay is an accurate positive predictor, but an inaccurate negative predictor, of mammalian developmental activity. We then evaluated C. elegans as a tool to identify mechanisms affecting toxicological outcomes among related compounds. The difference in developmental activity of structurally related fungicides in C. elegans correlated with their rate of metabolism. Knockdown of the cytochrome P450s cyp-35A3 and cyp-35A4 increased the toxicity to C. elegans of the least developmentally active compounds to the level of the most developmentally active. This indicated that these P450s were involved in the greater rate of metabolism of the less toxic of these compounds. We conclude that C. elegans based approaches can predict mammalian developmental activity and can yield plausible hypotheses for factors affecting the biological potency of compounds in mammals.
Evaluation of load sharing in HARTS while considering message routing and broadcasting (1993)

In this paper, we apply the load sharing (LS) mechanism proposed in [1, 2] to HARTS, an experimental distributed realtime system [3] currently being built at the Real-Time Computing Laboratory of the University of Michigan.
An investigation of acceptor-doped grain boundaries in (1996)

Grain boundary (GB) doped exhibits interesting electroceramic phenomena including varistor and barrier layer capacitor behaviour. We present here our investigation of GB acceptor-doped using analytical electron microscopy including electron holography. Mn was diffused into sintered polycrystalline to attain GBs which are rich in Mn. The presence and spatial extent of Mn at the GBs were analysed using x-ray emission spectroscopy (XES) and parallel electron energy loss spectroscopy (PEELS). The valence state of Mn was determined using PEELS to be predominantly +2. Finally, transmission high-energy electron holography was utilized to directly image and quantify the electrostatic potential and associated space-charge across the GBs directly. The holography results reveal a negatively charged GB with positive space-charge, indicating that Mn with a valence of +2 resides as an acceptor dopant on the Ti site at the GB core. The barrier height and local charge density distribution, including the Debye length, of the double Schottky barrier at the GB are derived from these holography results. This investigation demonstrates the usefulness of electron holography as a bulk-sensitive technique to probe the statics and dynamics of electrostatic field distribution and electrical charge across interfaces in technologically useful materials, and the need to employ diverse analytical techniques for such an investigation.
Synthesis, x-ray structure and nucleophilic properties of mixed bis(diene)tantalum complexes Ta(.eta.5-C5R5)(.eta.4-C4H6)(.eta.4-C6H10) (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis, x-ray structure and nucleophilic properties of mixed bis(diene)tantalum complexes Ta(.eta.5-C5R5)(.eta.4-C4H6)(.eta.4-C6H10)Takuji Okamoto, Hajime Yasuda, Akira Nakamura, Y. Kai, N. Kanehisa, and Nobutami KasaiCite this: Organometallics 1988, 7, 11, 2266–2273Publication Date (Print):November 1, 1988Publication History Published online1 May 2002Published inissue 1 November 1988https://pubs.acs.org/doi/10.1021/om00101a003https://doi.org/10.1021/om00101a003research-articleACS PublicationsRequest reuse permissionsArticle Views152Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
The mechanism of action of ethanolamine ammonia-lyase, an adenosylcobalamin-dependent enzyme. Evidence that the hydrogen transfer mechanism involves a second intermediate hydrogen carrier in addition to the cofactor. (1985)

Ethanolamine ammonia-lyase catalyzes the adenosylcobalamin (AdoCbl)-dependent conversion of ethanolamine to acetaldehyde and ammonia. During this reaction, a hydrogen atom migrates from the carbinol carbon of ethanolamine to the methyl carbon of acetaldehyde. Previous studies have shown that this migrating hydrogen equilibrates with the hydrogens on the 5'-(cobalt-linked) carbon of the cofactor. On the basis of those studies, a two-step mechanism for hydrogen transfer has been postulated in which the migrating hydrogen is first transferred from the substrate to the cofactor, then in a subsequent step is returned from the cofactor to the product. We now show that this migrating hydrogen is transferred not only to the cofactor, but also to a second acceptor at the active site. Hydrogens on this acceptor do not exchange with water during the course of the reaction, but are released to water when the enzyme is denatured. The catalytic significance of this second hydrogen acceptor was demonstrated by the findings that the transfer of hydrogen to this acceptor required both AdoCbl and active enzyme and that hydrogen at the second acceptor site could be washed out by unlabeled ethanolamine. On the basis of these results, we propose an expanded hydrogen transfer mechanism in which AdoCbl and the second acceptor site serve as alternative intermediate hydrogen carriers during the course of ethanolamine deamination.
Stochastic Variational Deep Kernel Learning (2016)

Deep kernel learning combines the non-parametric flexibility of kernel methods with the inductive biases of deep learning architectures. We propose a novel deep kernel learning model and stochastic variational inference procedure which generalizes deep kernel learning approaches to enable classification, multi-task learning, additive covariance structures, and stochastic gradient training. Specifically, we apply additive base kernels to subsets of output features from deep neural architectures, and jointly learn the parameters of the base kernels and deep network through a Gaussian process marginal likelihood objective. Within this framework, we derive an efficient form of stochastic variational inference which leverages local kernel interpolation, inducing points, and structure exploiting algebra. We show improved performance over stand alone deep networks, SVMs, and state of the art scalable Gaussian processes on several classification benchmarks, including an airline delay dataset containing 6 million training points, CIFAR, and ImageNet.
Hyperspectral imaging of retinal microvascular anatomy (2015)

Background: Hyperspectral image processing has been applied to many aspects of astronomical and earth science research. Furthermore, advances in computed tomographic imaging spectroscopy and diffraction grating design have allowed biological applications for non-invasive tissue analysis. Herein, we describe a hyperspectral computed tomographic imaging spectroscope (HCTIS) that provides high spatial, spectral and temporal resolution ideal for imaging biological tissue in vivo. Methods: We demonstrate proof-of-principle application of the HCTIS by imaging and mapping the microvascular anatomy of the retina of a model organism (rabbit) in vivo. The imaging procedure allows rapid and dense spectral sampling, is non-toxic, non-invasive, and easily adaptable to a commercially available fundus camera system. Results: HCTIS provides highly co-registered temporal, spatial and spectral data with resolution capable of reconstructing the fine vascular tree of the rabbit retina in vivo. Conclusions: We show that HCTIS allows for reliable and reproducible tissue classification and detection using signature discriminant analysis. Future applications of this system may provide promising diagnostic methods for diseases of many tissues.
Deposition of HfO2 on germanium and the impact of surface pretreatments (2004)

The deposition behavior of HfO2 by metalorganic chemical vapor deposition on germanium has been investigated. HfO2 films can be deposited on Ge with equally good quality as compared to high-k growth on silicon. Surface preparation is very important: compared to an HF-last, NH3 pretreatments result in smoother films with strongly reduced diffusion of germanium in the HfO2 film, resulting in a much better electrical performance. We clearly show that much thinner interfacial layers can be obtained, approximately half the thickness of what is typically found for depositions on silicon, suggesting the possibility of more aggressive equivalent oxide thickness∕leakage scaling.
Side Group Addition to the Polycyclic Aromatic Hydrocarbon Coronene by Proton Irradiation in Cosmic Ice Analogs (2002)

Ices at ∼15 K consisting of the polycyclic aromatic hydrocarbon coronene (C24H12) condensed either with H2O, CO2, or CO in the ratio of 1: 100 or greater have been subjected to MeV proton bombardment from a Van de Graaff generator. The resulting reaction products have been examined by infrared transmission-reflection-transmission spectroscopy and by microprobe laser-desorption laser-ionization mass spectrometry. Just as in the case of UV photolysis, oxygen atoms are added to coronene, yielding, in the case of H2O ices, the addition of one or more alcohol (iOH) and ketone (1CuO) side chains to the coronene scaffolding. There are, however, significant differences between the products formed by proton irradiation and the products formed by UV photolysis of coronene containing CO and CO2 ices. The formation of a coronene carboxylic acid (iCOOH) by proton irradiation is facile in solid CO but not in CO2, the reverse of what was previously observed for UV photolysis under otherwise identical conditions. This work presents evidence that cosmic-ray irradiation of interstellar or cometary ices should have contributed to the formation of aromatics bearing ketone and carboxylic acid functional groups in primitive meteorites and interplanetary dust particles. Subject headings: astrobiology — astrochemistry — comets: general — cosmic rays — ISM: molecules — molecular processes 1.