gebhart/patrepeval huggingface dataset:
Expanding the phenotypic spectrum of lipomatosis of the sciatic nerve: Early‐onset colonic diverticular disease (2020)

While the pathogenesis of the colonic diverticular disease is increasingly recognized as being multifactorial, our observations are consistent with the potential role of autonomic nervous system dysfunction affecting either the pelvic floor musculature, or the colon itself (or both) in a subset of patients with early-onset diverticular disease.
Identification of the Molecular Parameters that Govern Ordering Kinetics in a Block Copolymer Melt (1998)

The objective of this paper is to identify the molecular parameters that govern ordering kinetics in a diblock copolymer melt. Experimental data on the ordering kinetics were obtained by time-resolved depolarized light scattering after the sample was quenched from the disordered to the ordered state. The ordered state consisted of cylinders arranged on a hexagonal lattice. During the early stages of the disorder-to-order transition, a dilute suspension of ordered grains grow by invading the surrounding, disordered phase. A time-dependent Ginzburg−Landau model was used to relate the growth rate of these grains to molecular parameters. The growth rate is predicted to be proportional to the quench depth and chain radius of gyration and inversely proportional to the molecular relaxation time. Independent estimates of these parameters were obtained from small angle neutron scattering and rheological measurements. The experimentally determined grain growth rates are in good agreement with theoretical predictions, with no adjustable parameters.
Analysis of Caching and Replication Strategies for Web Applications (2007)

Developers often use replication and caching mechanisms to enhance Web application performance. The authors present a qualitative and quantitative analysis of state-of-the art replication and caching techniques used to host Web applications. Their analysis shows that selecting the best mechanism depends heavily on data workload and requires a careful review of the application's characteristics. They also propose a technique for Web practitioners to compare different mechanisms' performance on their own
Fabrication of gold nanorods-doped, bovine serum albumin microstructures via multiphoton excited photochemistry (2011)

In this study, three-dimensional (3D) crosslinked bovine serum albumin (BSA) microstructures containing gold nanorods (AuNRs) were fabricated via multiphoton excited photochemistry using Rose Bengal (RB) as the photoactivator. To retain AuNRs in the 3D crosslinked BSA microstructures, the laser wavelength was chosen for two-photon RB absorption for improved two-photon crosslinking efficiency, but not for enhancing the longitudinal plasmon resonance of AuNRs which may result in photothermal damage of AuNRs. Furthermore, with two-photon excitation of RB via AuNRs plasmonics, the laser power can be reduced by about 30%. As a result, 3D BSA microstructures containing AuNRs can be successfully fabricated. The AuNRs-doped BSA microstructures can be applied in biomedical scaffolds with plasmonic properties such as two-photon luminescence imaging and photothermal therapy.
Development of Digital Signage Modules composed of Mini-LEDs using Laser-Assisted Bonding (LAB) Technology (2020)

Light-emitting diodes (LED) based displays are highlighted because of their interesting features compared with others. Especially, the LED display with active matrix (AM) has additional advantages such as low power consumption, elimination of current cross talk, and so on. However, AM- driving LED displays are fabricated on active substrates with transistors so that there are many problems like high-cost, difficulty in enhancing yield, and repair problem. As an alternative, an AM-driving LED display on a passive substrate has been developed in this study. One pixel is composed of RGB mini-LEDs and a control IC, fabricated using the CMOS technology. It can decrease the cost of a substrate compared with other AM LED displays, and keep constant the complexity of substrate regardless of the variations of the pitch of mini-LEDs. To mount mini-LEDs and control ICs at the same time needs the technical innovations because they have different surface finishes. Moreover, there is no solder resist layer on a substrate because of the fine-pitch of mini-LEDs and control ICs in a single pixel. The Solder-on-Pad (SoP), fluxing underfill, and Laser-Assisted Bonding (LAB) technologies are developed to implement digital signage modules, successfully.
Relating Bone Strain to Local Changes in Radius Microstructure Following 12 Months of Axial Forearm Loading in Women (2020)

ABSTRACT Work in animal models suggest that bone structure adapts to local bone strain, but this relationship has not been comprehensively studied in humans. Here, we quantified the influence of strain magnitude and gradient on bone adaptation in the forearm of premenopausal women performing compressive forearm loading (n=11) and non-loading controls (n=10). High resolution peripheral quantitative computed tomography (HRpQCT) scans of the distal radius acquired at baseline and 12 months of a randomized controlled experiment were used to identify local sites of bone formation and resorption. Bone strain was estimated using validated finite element (FE) models. Trabecular strain magnitude and gradient were higher near (within 200 µm) formation versus resorption (p&lt;0.05). Trabecular formation and resorption occurred preferentially near very high (&gt;95th percentile) versus low (&lt;5th percentile) strain magnitude and gradient elements, and very low strain elements were more likely to be near resorption than formation (p&lt;0.05). In the cortical compartment, strain gradient was higher near formation versus resorption (p&lt;0.05), and both formation and resorption occurred preferentially near very high versus low strain gradient elements (p&lt;0.05). At most, 54% of very high and low strain elements were near formation or resorption only, and similar trends were observed in the control and load groups. These findings suggest that strain, likely in combination with other physiological factors, influences adaptation under normal loads and in response to a novel loading intervention, and represents an important step toward defining exercise interventions to maximize bone strength.
Comparison of Hafnium Precursors for the MOCVD of HfO2 for Gate Dielectric Applications (2003)

Hafnium oxide films were deposited on Si (100) substrates using metal-organic chemical vapor deposition (MOCVD) and evaluated for gate dielectric applications. For this study, two types of precursors were tested: an oxygenated one, Hf butoxide-mmp, and an oxygen-free one, Hf diethyl-amide. Depositions were carried out in the temperature range of 350–650°C. However, the discussion is focused on amorphous films. The films were compared on the basis of growth rate, phase development, density, interface characteristics, and electrical properties. A similar amorphous to polycrystalline phase transition temperature was found for both precursors. For low deposition temperatures the growth rate for the amide precursor was significantly higher than for the butoxide-mmp precursor and films prepared with the amide precursor contained a lower carbon impurity content than with the butoxide-mmp one. The dielectric constant was slightly higher for amorphous HfO2 deposited from the amide precursor than for the butoxide-mmp one. Only in respect to the trap density does the butoxide precursor seem advantageous.
Application of isomelezitose as an osmoprotectant for biological control agent preservation during drying and storage (2020)

Isomelezitose (IMZ) is of interest as a potential osmoprotectant, but it has not been previously characterised even though the structurally similar trisaccharide melezitose has been previously shown to have excellent protective qualities. The recent discovery that sucrose can be converted to IMZ during glucansucrase reactions suggests that IMZ might become an economical choice as an osmoprotectant for microbial inoculants, such as biological control agents (BCAs). Because of this opportunity, its osmoprotective function was explored in this work using two strains of Pseudomonas fluorescens that are BCAs used to control maladies of potatoes stored postharvest. BCA cell viability and growth recovery rate after drying and storage at 25 oC were assessed. The data showed that IMZ and impure IMZ reaction products can function similarly to melezitose and trehalose to significantly reduce viable cell and activity losses during air drying and storage. Biocontrol treatments formulated with IMZ retained the ability to suppress Fusarium dry rot disease by up to 50% under severe disease challenge, even after storage 28 d at 25 oC in vacuum-sealed bags. Biocontrol treatments with IMZ suppressed disease by 15–35% more thancontrols without any added osmoprotectant. Neither IMZ nor two impure enzyme reaction products impacted germination of dry rot causative Fusarium sambucinum conidia or subsequent hyphal growth under gnotobiotic conditions. For the first time, the osmoprotective capability of IMZ has been demonstrated and shown to be potentially superior to others previously reported, including the structurally related compound melezitose and the currently marketed disaccharide trehalose.
ChemInform Abstract: Synthesis of 6‐Imino‐5‐tetrahydro‐1H‐2‐pyrrolylidenhexahydro‐2,4‐pyrimidinediones as Intermediates for the Synthesis of C‐Azanucleosides. (2010)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
High Performance and Multipurpose Triarylamine-Enchained Semifluorinated Polymers (2012)

Transparent, film-forming fluorinated arylene vinylene ether (FAVE) polymers with enchained triarylamine (TAA) moieties were prepared and characterized. Control over fluoro-olefin content within the backbone, as a function of base, was confirmed and postpolymerization dehydrofluorination was shown to increase fluoroolefin content from 5 to 31 mol %. Thermal cross-linking was found to occur approximately 100 °C lower than in traditional FAVE polymers (ca. 160 °C). Electrochemical analysis demonstrated the enchained TAA retained its established electrochemical character. The latent reactivity of the TAA was explored via electrophilic aromatic substitution and formylation reactions toward precise functionalization for specific electro-optic applications and others.
Analysis of Narrowband Active Noise and Vibration Control Systems Using Parallel Adaptive Notch Filters (2008)

This paper analyzes narrowband active noise and vibration control (ANVC) systems using multiple second-order adaptive filters configured in parallel form with the filtered-x least mean square algorithm. Theoretical analysis of convergence of the algorithm is based on the autocorrelation and crosscorrelation matrices of the overall parallel structure. Analysis results show that extra harmonics are induced in the residual error because of using a single error signal to update all adaptive filters with different sinusoidal reference signals. An optimized filter-adapting method which uses bandpass filters to split the error signal into multiple bandlimited error signals according to frequencies of reference signals is proposed to improve the performance of narrowband ANVC systems in steady state. Computer simulations are conducted to verify analysis results and performance of the optimized narrowband ANVC system.
HVDC and the needs for modeling and simulation (2020)

High-voltage DC (HVDC) transmission technology has been considered as the key technology for bulk electric power transmission and network interconnection [1,2]. HVDC is also referred to as the earliest and most significant application of power electronics in the electric power system. The technology is consistently active in innovation and the development for energy integration, transmission, and grid interconnection. This chapter will first provide a brief description of the config-uration, classification, and development and then the discussions will be oriented to the needs for the modeling and simulation of HVDC.
A PIV Algorithm for Estimating Time-Averaged Velocity Fields (2000)

A PIV algorithm is presented for estimating time-averaged or phase-averaged velocity fields. The algorithm can be applied to situations where signal strength is not sufficient for standard cross correlation techniques, such as a low number of particle images in an interrogation spot, or poor image quality. The algorithm can also be used to increase the spatial resolution of measurements by allowing smaller interrogation spots than those required for standard cross correlation techniques. The quality of the velocity measurements can be dramatically increased by averaging a series of instantaneous correlation functions, before determining the location of the signal peak, as opposed to the commonly used technique of estimating instantaneous velocity fields first and then averaging the velocity fields. The algorithm is applied to a 30μm×300μm microchannel flow. [S0098-2202(00)00602-7]
Inactivation kinetics of Bacillus atrophaeus in liquid hydrogen peroxide for aseptic package sterilization (2022)

Liquid hydrogen peroxide is used as a common sterilant for the aseptic packaging materials. Based on the Food Safety Objective (FSO) for specific products, a surrogate organism, Bacillus atrophaeus, is used to validate the sterilization processes. This study aims to develop a methodology for the kinetic inactivation parameter estimation of B. atrophaeus. Spores of B. atrophaeus were challenged with various peroxide concentrations (20%, 28%, and 33%; v/v) and temperatures such as 23, 55, 71.1, and 82.2 °C. The log-linear and Weibull models were used for the inactivation models for liquid peroxide at different temperatures. The parameters were estimated at a reference temperature of 80 °C for log-linear and Weibull models. With peroxide concentrations of 20, 28, and 33%, the log-linear model estimated D values were 0.95, 0.47, and 0.08 min and z values were 94.67, 86.86, and 41 °C, respectively. The Weibull model δ values were 0.31, 0.23, and 0.05 min with a z value of 85.18, 81.23, and 41.39 °C for 20, 28, and 33% peroxide, respectively. The RMSE values varied from 0.60 to 0.79 log CFU/ml, the sum of the squares was between 27.3 and 39.7, and the parameters' relative errors were less than 6%.
Síntesis de ITQ-17 en ausencia de iones fluoruro (2005)

Referencia OEPM: P200101608.-- Fecha de solicitud: 03/07/2001.-- Titulares: Universidad Politécnica de Valencia (UPV), Consejo Superior de Investigaciones Científicas (CSIC).
Exact optimization conditions for discrete linear inverse problems (2013)

Recently, graph cut methods have been used with great success on discrete-label problems occurring in computer vision. Unfortunately, the presence of linear image mappings prevents the use of these techniques in image deconvolution. This work aims to expand the application of the successful graph-cut framework to linear inverse problems and deconvolution. We analyze the structure of linear inverse problems, showing the relationship of the sensing structure to graph non-representability of the problem and use insights from our analysis to present a class of linear operators that is graph representable. We propose a new method of variable relabeling that can transform a class of non-representable problems of this type to corresponding ones which are graph representable, thus allowing the use of graph-cut techniques for these problems.
Single contact electron beam induced current technique for solar cell characterization (2013)

This paper reports the first demonstration of single contact electron beam induced current (SCEBIC) technique on multicrystalline silicon (mc-Si) solar cells. A lumped single-diode analytical model is also proposed to theoretically explain the SCEBIC phenomenon within solar cells as well as the current transient characteristics of the major model parameters, such as shunt resistance R <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">sh</sub> , junction capacitance C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">j</sub> , and parasitic capacitance C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">s</sub> . The accuracy of the analytical model is then verified using PSPICE simulations, which show a close match with the experimental results. It is found that a large value of parasitic capacitance C <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">s</sub> is necessary to achieve good SCEBIC signal strength with a relatively low signal-to-noise ratio (SNR), and this is realized experimentally by adopting a metal enclosure in the measurement setup. In addition, the advantage of SCEBIC over conventional double-contact method is also demonstrated by SCEBIC characterization of partially processed solar cells, which clearly illustrates the high degree of flexibility of SCEBIC in solar cell characterization.
Automatic Lymphocyte Detection in H&E Images with Deep Neural Networks. (2016)

Automatic detection of lymphocyte in H&E images is a necessary first step in lots of tissue image analysis algorithms. An accurate and robust automated lymphocyte detection approach is of great importance in both computer science and clinical studies. Most of the existing approaches for lymphocyte detection are based on traditional image processing algorithms and/or classic machine learning methods. In the recent years, deep learning techniques have fundamentally transformed the way that a computer interprets images and have become a matchless solution in various pattern recognition problems. In this work, we design a new deep neural network model which extends the fully convolutional network by combining the ideas in several recent techniques, such as shortcut links. Also, we design a new training scheme taking the prior knowledge about lymphocytes into consideration. The training scheme not only efficiently exploits the limited amount of free-form annotations from pathologists, but also naturally supports efficient fine-tuning. As a consequence, our model has the potential of self-improvement by leveraging the errors collected during real applications. Our experiments show that our deep neural network model achieves good performance in the images of different staining conditions or different types of tissues.
Nucleic Acid—Gold Nanoparticles Conjugates as Mimics of MicroRNA* (2020)

Recent advances in nanotechnology have led to promising constructs for drug delivery, disease detection, and molecular diagnostics. Polyvalent oligonucleotide-functionalized gold nanoparticles have emerged as new and robust tools for drug delivery, analyte detection, and gene regulation in biological systems. This chapter reports the synthesis and characterization of novel miRNA-gold nanoparticle conjugates that are capable of entering cells without the aid of cationic co-carriers, regulating the expression of multiple genes and controlling cellular behavior. The prototype miRNA mimics consist of 13 ± 1 nm gold nanoparticles, each functionalized with a monolayer of double-stranded alkylthiol-modified RNA molecules. Taken together, the ability of polyvalent nucleic acid-functionalized nanoparticles to enter cells without the aid of cationic lipids and polymers, coupled with their demonstrated function as endogenous miRNAs, makes them promising new tools for studying miRNA function as well as important new candidates for miRNA replacement therapies.
Analysis of trade-off relationships in resist patterns delineated using SFET of Selete (2010)

We investigated the relationship between line edge roughness (LER) and the chemical gradient using the fourth Selete Standard Resist (SSR4). Two-dimensional (half-pitch and exposure dose) matrices of resist line width and LER were analyzed on the basis of the sensitization mechanisms of chemically amplified resists for extreme ultraviolet (EUV) lithography. The latent images of resist patterns were successfully reproduced by assuming that LER is inversely proportional to the chemical gradient. The product of LER and normalized chemical gradient was approximately 0.2 for SSR4.
An asymmetric twin-waveguide high-bandwidth photodiode using a lateral taper coupler (2001)

We describe a high-bandwidth high-responsivity low-polarization sensitivity p-i-n photodiode based on an integratable asymmetric twin-waveguide structure. Incident light is collected by a diluted large-fiber guide followed by transfer to a thin-coupling waveguide using a low-loss lateral-taper coupler. The light is finally absorbed by the uppermost In/sub 0.53/Ga/sub 0.47/As layer. The device has a responsivity of (0.75/spl plusmn/0.03) ampere per watt and a polarization sensitivity of /spl les/0.4 dB. The measured electrical 3 dB bandwidth is /spl ges/40 GHz. The responsivity is comparable with the best 40-GHz waveguide p-type-intrinsic-n-type photodiodes, while the twin-waveguide design provides a single-epitaxial growth step and a simple means of fabrication with possibility for monolithic integration of the photodiodes with other optical components, such as semiconductor optical amplifiers and in-plane waveguide filters.
Gaussian-2 theory: Use of higher level correlation methods, quadratic configuration interaction geometries, and second-order Mo/ller–Plesset zero-point energies (1995)

The performance of Gaussian-2 theory is investigated when higher level theoretical methods are included for correlation effects, geometries, and zero-point energies. A higher level of correlation treatment is examined using Brueckner doubles [BD(T)] and coupled cluster [CCSD(T)] methods rather than quadratic configuration interaction [QCISD(T)]. The use of geometries optimized at the QCISD level rather than the second-order Mo/ller–Plesset level (MP2) and the use of scaled MP2 zero-point energies rather than scaled Hartree–Fock (HF) zero-point energies have also been examined. The set of 125 energies used for validation of G2 theory [J. Chem. Phys. 94, 7221 (1991)] is used to test out these variations of G2 theory. Inclusion of higher levels of correlation treatment has little effect except in the cases of multiply-bonded systems. In these cases better agreement is obtained in some cases and poorer agreement in others so that there is no improvement in overall performance. The use of QCISD geometries yields significantly better agreement with experiment for several cases including the ionization potentials of CS and O2, electron affinity of CN, and dissociation energies of N2, O2, CN, and SO2. This leads to a slightly better agreement with experiment overall. The MP2 zero-point energies gives no overall improvement. These methods may be useful for specific systems.
Single-Step Endocervical and Ectocervical Balloon Collector (2001)

Papers on Current Clinical and Basic Investigation: Poster Sessions Monday, April 30, 2001: Cervical Disease: PDF Only