gebhart/patrepeval huggingface dataset:
Reversible Assembly and Disassembly of Gold Nanorods Induced by EDTA and Its Application in SERS Tuning (2011)

A facile and reversible method for assembling and disassembling gold nanorods (GNRs) using a common chelating agent, ethylenediaminetetraacetic acid (EDTA), is reported. Assembly was induced by the electrostatic interaction between the cetyltrimethylammonium bromide (CTAB) bilayer present on GNRs and EDTA. At lower concentrations of EDTA, end-to-end assembled chains were formed. At higher concentrations of EDTA, these chains come together to form sheet-like structures. The complex of CTAB and EDTA, being labile, disassembles in the presence of stronger chelating agents. Upon addition of metal ions having higher formation constants, EDTA detaches from the GNRs and forms stronger complexes with metal ions, resulting in disassembly. Characteristic changes were observed in the UV/vis spectra. Addition of EDTA resulted in a red shift of longitudinal surface plasmon (LSP) resonance at lower concentrations, indicating an end-to-end assembly. At higher concentrations, the characteristic of side-by-side assembly was seen in the UV/vis spectra. TEM analysis proved the existence of end-to-end chains at lower concentrations of EDTA and side-by-side assembled sheet-like structures at higher concentrations. The addition of metal ions induced disassembly. Even 2 ppb of metal ion was detected using the spectral changes. Disassembly was studied in detail, taking Pb(II) as the model system. Upon addition of Pb(II), TSP showed a blue shift and decreased in intensity while the LSP showed a red shift and increased in intensity. A new peak at a higher wavelength region emerged, pointing to the existence of both side-by-side and end-to-end assembly in the system. TEM analysis showed that the disassembly involves the formation of bundled chains which may be the reason for the observed spectral changes. Surface-enhanced Raman scattering (SERS) activity of the system could be tuned by controlling the concentration of EDTA and the metal ion, Pb(II).
Efficient supercontinuum generation in a ultra compact silica highly nonlinear fiber (2006)

HNLF with 50 mum cladding and optimized dispersion for efficient supercontinuum generation is designed and fabricated. High quality SC light was generated by 1 km HNLF wound on outer diameter of phi50 mm with 100 mW input power
Synthesis and langmuir-blodgett(LB) film properties of functionalα,ω-diamine amphiphilic materials (2000)

We have investigated the synthesis and ultrathin film forming properties of α,ω-diamine derivatives. The amphiphiles were synthesized as precursors to the formation of ionene polymers. Two materials were investigated: oligothiophene and azobenzene functional groups. These type of materials are of great interest for the preparation of ultrathin film layers with applications for photochemical regulation of liquid crystal (LC) orientation, optical storage media, and electroluminescent displays. Azobenzene and its derivatives are well known photochemical systems exhibiting the reversible cis-trans photoisomerization. Conjugated oligothiophene derivatives, exhibit interesting optical and electronic properties for applications such as light emitting diodes (LED)s, Schottky diodes, and thin film field-effect transistors (TFT). The two amphiphiles behaved very differently as Langmuir monolayers and LB films. Dye aggregation was observed with the azobenzene derivatives compared with the oligothiophenes.
Base‐Free Iron Catalyzed Transfer Hydrogenation of Esters Using EtOH as Hydrogen Source (2018)

Herein, we report on the use of the iron pincer complex Iron-MACHO-BH, in the base-free transfer hydrogenation of esters with EtOH as a hydrogen source. More than 20 substrates including aromatic and aliphatic esters and lactones were reduced affording the desired primary alcohols and diols with moderate to excellent isolated yields. It is also possible to reduce polyesters to the diols with this method, enabling a novel way of plastic recycling. Reduction of the renewable substrate methyl levulinate proceeds to form 1,4-pentanediol directly. The yields are largely governed by the equilibrium between the alcohol and the ethyl ester.
DIRECT STUDIES OF NEEL (OR BLOCH) LINE DYNAMICS (1988)

Néel (or Bloch) line dynamics has been investigated in garnet epilayers characterized by huge and moderate damping parameters. Direct pressure velocities are found to be in fair agreement with expected values. Velocity saturation is, however, observed in moderately damped material. The gyrotropic coupling to wall motion is shown to produce a variety of line displacement behaviours.
Deep level traps in semi‐polar n‐GaN grown on patterned sapphire substrate by metalorganic vapor phase epitaxy (2016)

Deep level traps in the low dislocation density, 5.1 × 10 7 cm −2 , semi‐polar GaN (11–22), grown on patterned sapphire substrate was characterized for the first time using deep level transient spectroscopy (DLTS) and deep level optical spectroscopy (DLOS). DLTS revealed two deep levels E T1 = E C − 0.24 eV and E T2 = E C − 0.41 eV in the semi‐polar GaN layer. The dominant trap E T1 = E C − 0.24 eV with a density of 6.1 × 10 14 cm −3 , is documented in c ‐plane and m ‐plane GaN. It is attributed to V N . DLOS revealed two deep level traps E T3 = E C − 1.20 eV and E T4 = E C − 3.26 eV. The dominant level E T4 = E C − 3.26 eV is also observed in non‐polar m ‐plane GaN grown on sapphire and it is attributed to C N acceptor‐like state. The total trap density of the semi‐polar GaN is about 2 × 10 16 cm −3 , which is comparable with that found in c ‐plane GaN.
Device-Enhanced Password Protocols with Optimal Online-Offline Protection (2016)

We introduce a setting that we call Device-Enhanced PAKE (DE-PAKE), where PAKE (password-authenticated key exchange) protocols are strengthened against online and offline attacks through the use of an auxiliary device that aids the user in the authentication process. We build such schemes and show that their security, properly formalized, achieves maximal-attainable resistance to online and offline attacks in both PKI and PKI-free settings. In particular, an online attacker must guess the user's password and also corrupt the user's auxiliary device to authenticate, while an attacker who corrupts the server cannot learn the users' passwords via an offline dictionary attack. Notably, our solutions do not require secure channels, and nothing (in an information-theoretic sense) is learned about the password by the device (or a malicious software running on the device) or over the device-client channel, even without any external protection of this channel. An attacker taking over the device still requires a full online attack to impersonate the user. Importantly, our DE-PAKE scheme can be deployed at the user end without the need to modify the server and without the server having to be aware that the user is using a DE-PAKE scheme. In particular, the schemes can work with standard servers running the usual password-over-TLS authentication. We use these protocols to implement a practical DE-PAKE system and we evaluate its performance. To improve usability the implemented system utilizes automated and user-transparent data channel between the mobile device and the client, falling back to localized communication if the device looses primary connectivity.
Factor structure for puncture skills in hemodialysis (2008)

血液透析スタッフはバスキュラーアクセスの長期維持や患者満足度向上などのために，穿刺技術向上に研鑽を重ねている．穿刺技術に対する評価は，医療スタッフや患者など，それぞれの立場や，判断材料によって異なることが考えられる．穿刺技術を効果的に向上させるためには，患者の目から見た望ましい技能，および専門的な技能構成を明らかにすることが必要である．そのため，穿刺評価に対する患者・スタッフによるそれぞれの技能評価の因子構造を解明し，それにより総合的に判断する基礎情報を提供することを目的とする．医療スタッフおよび患者に共通の調査票を用い，37名の医療スタッフならびに116名の患者から回答を収集し，これらの患者・スタッフそれぞれのサンプルに因子分析を適用した結果，若干異なるものの類似する7因子による穿刺技能評価の因子構造を抽出した（累積寄与率は，患者，スタッフそれぞれ，60.8％，および65.5％）．患者，スタッフの回答サンプルから「技能・安定感」，「接し易さ」，「誠実さ」，「技能指向」，「感染への配慮」，「患者指向」などの因子が共通して抽出された．本研究では患者・スタッフ共通の質問項目とともにスタッフを対象に必要技能に対して，より詳細な項目を含む付加的な質問に対する回答も得ている．これらの項目を含めた因子分析により，「判断力」，「観察力・思慮深さ」，「指導力」，「技術的積極性」といった，個別技能が技能評価因子として抽出された．さらに，穿刺技能の総合評価得点を目的変数，患者回答データから抽出した7つの技能評価因子を説明変数とした重回帰分析を行った結果，「技能・安定感」のみに有意な関係が認められ，その決定係数は0.928であった．これらの結果から，血液透析スタッフの穿刺技術に対して，患者はスタッフの総合的技能，穿刺時の安定感で評価していることが明らかとなった．
Effects of the GaN and AlN nucleation layers on the crack-free AlGaN templates (2008)

This paper reports the effects of GaN and AlN nucleation layers (NLs) on the characteristics of the subsequently grown AlGaN templates, which were grown by a two-step growth method on sapphire substrates using metal-organic chemical vapor deposition. The in situ monitored reflectance spectra reveal that the thickness variation in AlGaN templates grown on the GaN NL is much smaller than that on the AlN NL. X-ray diffraction patterns show that the AlGaN template with a GaN NL exhibits a better crystalline quality as compared to that with an AlN NL. Observed from the transmission electron microscopy, it is also shown that the dislocation density of the AlGaN template with a GaN NL can be substantially reduced. In addition, the fabricated light-emitting diodes from the AlGaN template with a GaN NL exhibit a lower forward voltage, a lower series resistance, a lower leakage current, and a narrower linewidth of electroluminescence peak than those with the AlN NL.
A Comparison of the H2 Sorption Capacities of Isostructural Metal–Organic Frameworks With and Without Accessible Metal Sites: [{Zn2(abtc)(dmf)2}3] and [{Cu2(abtc)(dmf)2}3] versus [{Cu2(abtc)}3] (2008)

The isostructural metal–organic frameworks [{Zn2(abtc)(dmf)2}3] (1 a), [{Cu2(abtc)(dmf)2}3] (2 a), and [{Cu2(abtc)}3] (2 b; H4abtc=1,1′-azobenzene-3,3′,5,5′-tetracarboxylic acid) have high sorption capacities for H2, N2, CO2, and CH4. Solid 2 b, which has accessible metal sites (AMSs), has a higher H2 adsorption capacity than 1 a or 2 a (see picture; T=77 K), neither of which have AMSs, because of its lower molecular weight and greater isosteric heat of H2 adsorption. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z801488_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Fabrication of magnetic micro/nanotweezers functionalized and dispersed in solution for bio (2013)

International audience
Supplementary Figure S1 from NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases (2023)

&lt;p&gt;Supplementary Figure S1 - PDF file 32K, Chemical structure of NMS-E973&lt;/p&gt;
3.4 Mass Spectrometries (2021)

This glossary provides a formal vocabulary of terms for concepts in surface analysis and gives clear definitions to those who utilize surface chemical analysis or need to interpret surface chemical analysis results but are not themselves surface chemists or surface spectroscopists.
DNA Vaccination and the Immune Responsiveness of Neonates (2000)

Neonates often respond poorly to conventional vaccines or microbial infections. Immaturity of the immune system has been considered to play a role in this regard. However, accumulating evidence shows that in certain conditions, neonatal inoculation of antigens leads to protective immunity. In the particular case of DNA vaccines administered to neonates, the rule is immunity rather than tolerance. Exceptions to the rule give opportunities to further understand the neonatal responsiveness and the mechanism of DNA vaccination. Due to the very nature of the vaccine vector, inhibition of neonatal DNA vaccination by maternal antibodies may be limited to the humoral immunity.
10-Camphorsulfonyl Chloride1 (2001)

(1R) [21286-54-4] C10H15ClO3S (MW 250.75) (1S) [39262-22-1] (±) [6994-93-0] (enantiomeric excess determination;2 chemical resolution;3 synthesis of chiral auxiliaries;4 chiral precursor for natural product synthesis;1 synthesis of chiral reagents5) Physical Data: mp 65–67 °C; (1S)-(+): [α]D + 32.1° (c 1, CHCl3). Solubility: sol CH2Cl2; slightly sol ether; insol H2O. Form Supplied in: both enantiomers and the racemic sulfonyl chloride are commercially available. Preparative Method: can be prepared from 10‐Camphorsulfonic Acid upon treatment with Phosphorus(V) Chloride or Thionyl Chloride.6 Purification: crystallized from hexane or from MeOH. Handling, Storage, and Precautions: corrosive and moisture-sensitive. This reagent should be handled in a fume hood.
Stabilization of a Labile cis-Azobenzene Derivative with Amphiphilic Cyclodextrins (1988)

Abstract The cis-isomer of p-Methyl Red (cis-p-MR) was appreciably stabilized by inclusion in equimolar amphiphilic heptakis(6-alkylamino-6-deoxy)cyclodextrins (CnN-CDs) in either chloroform solution or the Langmuir–Blodgett (LB) films, as compared with that in the isolated state. Amino moieties in the cyclodextrin derivatives were found to be essential for a tight inclusion of p-MR and also for the stabilization of cis-isomer.
A novel solution for high speed internet over the oceans (2018)

The cellular network range over the oceans is limited to about 15 km from the shore in most places. The service providers do not have any incentive to extend the coverage further. However, marine fishermen who routinely spend 5 to 7 days at the ocean on a single fishing trip are severely impacted by this. They go as far away as 120 km from the shore on some occasions and are completely cut off from the land during their fishing trips. Also, they are generally poor and need an economical solution to stay connected. We have developed and successfully prototyped an affordable solution based on a multi-level auto-reconfigurable backhaul infrastructure network. It uses long range (LR) Wi-Fi and extends the connectivity to 60 km and beyond over the oceans using heterogeneous networks and relay nodes. Multiple field trials involving up to four boats over the Arabian Sea have yielded consistent and repeatable results even under rough sea states. Additional experiments conducted over the backwaters by scaling up the network further have also yielded positive results. This work provides a detailed description of the architected solution and the results obtained.
ChemInform Abstract: POLYMER‐BASED SENSITIZERS FOR PHOTOOXIDATIONS PART 2 (1975)

Abstract Ein Sensibilisator (PRB) des Titeltjyps wird nach bekannter Methode aus chlormethyliertem Styrol‐Divinylbenzoil‐Kopolymerenfund Bengalrosa dargestellt und bei der Photolyse von mit Sauerstoff gesättigtenLösungen der Verbindungen (I), (III), (VI), (VIII) angewendet.
Thermal challenges for heterogeneous 3D ICs and opportunities for air gap thermal isolation (2014)

Thermal crosstalk within a heterogeneous 3D IC results in higher temperatures for low-power dice; this is particularly true in memory-logic, photonic-logic, and MEMS-logic stacks. The elevated temperatures may consequently impact the performance of the low-power devices. This paper describes a thermal solution for both heat removal as well as thermal isolation within a 3D chip stack. Based on the evaluated memory-logic 3D architecture and compared to conventional air-cooling, the proposed technologies reduce the maximum temperature of the memory die from 75.6 °C to 36.7 °C and processor die from 75.9 °C to 60.1 °C.
Nucleotide sequence of a cDNA for the bovine myristoylated alanine-rich C kinase substrate (MARCKS) (1989)

Journal Article Nucleotide sequence of a cDNA for the bovine myristoylated alanine-rich C kinase substrate (MARCKS) Get access Deborah J. Stumpo, Deborah J. Stumpo Howard Hughes Medical Institute LaboratoriesDurham, NC and Section of Diabetes and Metabolism, Division of Endocrinology, Metabolism and Genetics, Departments of Medicine and Biochemistry, Duke University Medical CenterDurham, NC 27710 Search for other works by this author on: Oxford Academic PubMed Google Scholar Jonathan M. Graff, Jonathan M. Graff Howard Hughes Medical Institute LaboratoriesDurham, NC and Section of Diabetes and Metabolism, Division of Endocrinology, Metabolism and Genetics, Departments of Medicine and Biochemistry, Duke University Medical CenterDurham, NC 27710 Search for other works by this author on: Oxford Academic PubMed Google Scholar Katherine A. Albert, Katherine A. Albert 1Laboratory of Molecular and Cellular Neuroscience, The Rockefeller UniversityNew York, NY 10021-6399, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Paul Greengard, Paul Greengard 1Laboratory of Molecular and Cellular Neuroscience, The Rockefeller UniversityNew York, NY 10021-6399, USA Search for other works by this author on: Oxford Academic PubMed Google Scholar Perry J. Blackshear Perry J. Blackshear Howard Hughes Medical Institute LaboratoriesDurham, NC and Section of Diabetes and Metabolism, Division of Endocrinology, Metabolism and Genetics, Departments of Medicine and Biochemistry, Duke University Medical CenterDurham, NC 27710 Search for other works by this author on: Oxford Academic PubMed Google Scholar Nucleic Acids Research, Volume 17, Issue 10, 25 May 1989, Pages 3987–3988, https://doi.org/10.1093/nar/17.10.3987 Published: 25 May 1989 Article history Received: 07 April 1989 Published: 25 May 1989
University of Twente at the TREC 2008 Enterprise Track: using the Global Web as an expertise evidence source (2008)

This paper describes the details of our participation in ex-pert search task of the TREC 2007 Enterprise track. 1.
Phantom criteria for qualification of brain FDG and amyloid PET across different cameras (2016)

The proposed phantom test criteria facilitate standardization and qualification of brain FDG and amyloid PET images and deserve further evaluation by future multicenter clinical studies.
Synthesis of Neutral, Water-Soluble Oligo–Ethylene Glycol-Containing Dendronized Homo- and Copolymers of Generations 1, 1.5, 2, and 3 (2014)

Oligo-ethylene glycol-containing dendronized monomers MG1, MG1.5, MG2, and MG3 were synthesized in a particularly easy fashion on the gram scale involving only few steps. Their corresponding homopolymers (PG1, PG1.5, PG2, and PG3) and copolymers (PG1co2, PG1co3, and PG2co3) were synthesized via free radical polymerization. All the polymers are soluble in water and also in organic solvents such as DCM, CHCl3, 1,4-dioxolane, DMF, and DMSO. Their glass transition temperatures (Tg) are in the range −68 °C < Tg < −48 °C and thus rather low. All polymers show thermoresponsive behavior which was investigated by turbidity measurements. Interestingly, a 1:1 mixture of homopolymers PG1 and PG2 behaves identical with PG1 alone, while the collapse curve of copolymer PG1co2 is almost superimposable with that of PG2 alone. Thus, in the former case PG1 dominates the thermoresponsive behavior while in the latter this is done by the G2-dendrons in the copolymer. Finally, the polymer chains were visualized by AFM, confirming the rod-like behavior of these rigidified polymers.
Cutting properties of deposited amorphous silicon in ultra-precision machining (2018)

The widely used amorphous silicon material is often a deposited one. It is mainly applied in the electronic industry and shows to be a promising candidate for optical devices. The mechanical cutting of deposited amorphous silicon has not been reported so far, while ultra-precision machining of such material for optical devices can be superior to a lithographic approach. In this article, for the first time, cutting properties of deposited amorphous silicon are compared with those of single crystal silicon and polycrystalline silicon, using plunge cut experiment. It is found that the critical depth of cut (CDC) and cutting forces for the amorphous silicon are close to those of single crystalline silicon in the easy-to-cut orientation. In comparison to the polycrystalline silicon, amorphous silicon has higher CDC and lower cutting force. This may allow machining of amorphous optical devices on different semiconductors and/or moulds on various materials with enhanced and isotropic CDC, reduced tool wear and simplified cutting control.
PTEN loss as a context-dependent determinant of patient outcomes in obese and non-obese endometrioid endometrial cancer patients. (2013)

5521 Background: Aberrations in the PI3K pathway, the central relay pathway of insulin signals, occur in the majority of endometrioid endometrial cancers. We explored the prognostic utility of PIK3CA, PIK3R1, and PTEN mutations, as well as PTEN protein loss, in the context of patient weight. Methods: Patients (pts) treated for endometrial cancer at a single institution between 2000 and 2009 were identified. Tumor DNA was extracted and exome sequencing performed using a 454 platform with confirmation of hot spot mutations by Sequenom. PTEN protein expression was determined by immunohistochemistry and reverse phase protein array (RPPA). RPPA for 135 relevant proteins was performed using a GeneTAC arrayer to create spot arrays. Slides were scanned, analyzed, and quantitated using Microvigene software. Results: One hundred eighty seven endometrioid endometrial cancer specimens were included. Median age was 61 yrs and median body mass index (BMI) was 33.5 kg/m 2 . The majority of pts had early stage (I/II) disease (74%) and grade 2 tumors (66%). There were no statistically significant associations between progression free survival (PFS) and PIK3CA, PIK3R1, PTEN mutation or loss. However, when stratified by BMI, PTEN loss was associated with a significantly improved PFS (p&lt; 0.006) in obese (BMI &gt; 30 kg/m 2 ) pts. In contrast, PTEN loss was associated with a worse PFS (p&lt;0.06) in non-obese (BMI &lt; 30 kg/m 2 ) pts. Further, PTEN loss in obese and non-obese pts resulted in distinct protein changes by RPPA, with canonical PI3K pathway activation observed only in the non-obese PTEN loss cohort. PTEN loss in obese pts was associated with decreased expression of CATENIN and phosphorylated FOXO3A. Conclusions: These data suggest the impact of PTEN loss on tumor biology and clinical outcomes must be interpreted in the context of BMI and provide potential explanation for prior discrepant findings on effect of PTEN status on prognosis in endometrial cancer. These data describe a clinically important interaction between metabolic state and tumor genetics that could potentially unveil the biologic underpinning of obesity-related cancers and may be relevant to ongoing clinical trials with PI3K pathway inhibitors.
Generation of H_2, O_2, and H_2O_2 from water by the use of intense femtosecond laser pulses and the possibility of laser sterilization (1996)

An intense femtosecond Ti-sapphire laser pulse was focused into water, leading to self-focusing. Apart from generating a white light (supercontinuum), the intense laser field in the self-focusing regions of the laser pulse dissociated the water molecules, giving rise to hydrogen and oxygen gas as well as hydrogen peroxide. Our analysis shows that the formation of free radicals O, H, and OH preceded the formation of the stable products of H(2), O(2), and H(2)O(2). Because O radicals and H(2)O(2) are strong oxydizing agents, one can take advantage of this phenomenon to design a laser scheme for sterilization in medical and biological applications.