gebhart/patrepeval huggingface dataset:
A High-Efficiency and Long-Distance Power-Relay System With Equal Power Distribution (2019)

This paper proposes a wireless power repeater system for long-distance and multiple-load applications with equal power load at each repeater. Each repeater performs as a power relay that not only receives and transmits power but also supplies power to its local load. The main contribution of this paper is to provide the design methodology of a distributed power-relay system. First, it provides the mathematical model of the power distribution among the power relays, indicating that the inductances and resistances can affect the power distribution. Second, it provides the power transfer capability of a power-relay system based on the quality factor and efficiency requirement, indicating the maximum achievable number of power relays in a system. Aiming at practical applications, this paper provides the guideline for the circuit parameter design to achieve equal power distribution. Two typical examples are proposed to realize equal power distribution. The identical <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\text{M}_{\text {n}}$ </tex-math></inline-formula> and different <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\text{R}_{\text {n}}$ </tex-math></inline-formula> examples are selected for implementation. The coil size is <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$400\,\,\text {mm}\times 400$ </tex-math></inline-formula> mm, and the eight power relays achieve a transfer distance of 3.2 m with a total power of 760 W and an efficiency of 70%. Experimental results validate that equal power distribution is achieved for the multiple loads across a long distance. Each power relay dissipates about 95-W power in its local load with a power variation limited to ±2%.
Urinary excretions of lipocalin-type prostaglandin D synthase predict renal injury in type-2 diabetes: a cross-sectional and prospective multicentre study (2008)

Urinary L-PGDS excretions reflect the current increased permeability of injured glomerular capillary walls and better predict the future status of renal injury in type-2 diabetes with <30 mg/gCr albuminuria.
The SNAP project: design of floating point arithmetic units (2002)

In recent years computer applications have increased in their computational complexity. The industry wide usage of performance benchmarks, such as SPECmarks, and the popularity of 3D graphics applications forces processor designers to pay particular attention to implementation of the floating point unit, or FPU. The paper presents results of the Stanford subnanosecond arithmetic processor (SNAP) research effort in the design of hardware for floating point addition, multiplication and division. We show that one cycle FP addition is achievable 32% of the time using a variable latency algorithm. For multiplication, a binary tree is often inferior to a Wallace tree designed using an algorithmic layout approach for contemporary feature sizes (0.3 /spl mu/m). Further, in most cases two bit Booth encoding of the multiplier is preferable to non Booth encoding for partial product generation. It appears that for division, optimum area performance is achieved using functional iteration, and we present two techniques to further reduce average division latency.
mBLAST: Keeping up with the Sequencing Explosion for (Meta) Genome (2013)

Recent advances in next-generation sequencing technologies require alignment algorithms and software that can keep pace with heightened data production. Standard algorithms, especially protein similarity searches, represent significant bottlenecks in analysis pipelines. For metagenomic approaches in particular, it is now often necessary to search hundreds of millions of sequence reads against large databases. Here we describe mBLAST, an accelerated search algorithm for translated and/or protein alignments to large datasets based on the Basic Local Alignment Search Tool (BLAST) and retaining the high sensitivity of BLAST. The mBLAST algorithms achieve substantial speed up over the National Center for Biotechnology Information (NCBI) programs BLASTX, TBLASTX and BLASTP for large datasets, allowing analysis within reasonable timeframes on standard computer architectures. In this article, the impact of mBLAST is demonstrated with sequences originating from the microbiota of healthy humans from the Human Microbiome Project. mBLAST is designed as a plug-in replacement for BLAST for any study that involves short-read sequences and includes high-throughput analysis. The mBLAST software is freely available to academic users at www.multicorewareinc.com.
Cavity optomechanics for trace gas detection (2021)

We present a new concept of spectroscopic sensor based on optomechanical transduction. The optomechanical interaction induces a strong dependence of the mechanical properties of a membrane on the optical losses induced by the absorption of an intra-cavity gas. Optically quantifying the variation of these parameters allows us to measure the gas concentration. The system is analysed theoretically and numerically with FEM simulation to estimate the responsivity. Fiber Bragg Grating based Extrinsic Fiber Fabry-Pérot cavity of various types as well as integrated mid-infrared cavities with highly reflective Bragg multilayers mirrors and silicon or stoichiometric silicon nitride membrane are studied.
Thermally Stable Passivation toward High Efficiency Inverted Perovskite Solar Cells (2020)

Although metal halide perovskite photovoltaics have shown an unprecedented rise in power conversion efficiency (PCE), they remain far from their theoretical PCE limit. Among the highest efficiencies to date are delivered when polycrystalline films are enhanced via “molecular passivation”, but this can introduce new instabilities, in particular under severe accelerated aging conditions (e.g., at 85 °C in the dark or under full spectrum simulated sunlight). Here, we utilize a benzylammonium bromide passivation treatment to improve device performance, achieving the champion stabilized power output (SPO) of 19.5 % in a p-i-n device architecture. We correlate the improved device performance with a significant increase in charge carrier diffusion lengths, mobilities, and lifetimes. Furthermore, treated devices maintain an increased performance during 120 h combined stressing under simulated full spectrum sunlight at 85 °C, indicating that enhancement from this passivation treatment is sustained under harsh accelerated aging conditions. This is a crucial step toward real-world operation-relevant passivation treatments.
Эффекты физической реабилитации у ликвидаторов аварии на ЧАЭС с хронической бронхолегочной патологией (2008)

The influence of physical rehabilitation on the dynamics of functional state of Chernobyl atomic electric station accident liquidators. Physical reabilitation improves tolerance to physical execises, but doest influence pulmonary function probably because of the fact that special exercises for respiratory muscle werent included intothe programm of rehabilitation.
Reactive oxygen metabolites, neutrophils, and the pathogenesis of ischemic-tissue/reperfusion (1993)

Considerable research effort has been directed at elucidating the mechanisms underlying the pathophysiologic alterations associated with reperfusion (reoxygenation) of ischemic (hypoxic) tissues. As a consequence of this intensive effort, a large body of evidence has accumulated, implicating a role for reactive oxygen metabolites and activated granulocytes in the genesis of postischemic cellular dysfunction. Figure 1 summarizes a hypothesis that has been proposed to explain the interaction of xanthine oxidase-derived oxidants, granulocyte infiltration, and the microvascular and parenchymal cell dysfunction that occurs in postischemic tissues. According to this scheme, xanthine oxidase-derived oxidants, produced at reperfusion, initiate the formation and release of proinflammatory agents, which subsequently attract and activate granulocytes. The activated neutrophils adhere to the microvascular endothelium, extravasate, and release cytotoxic oxidants and proteases, which contribute to tissue dysfunction. The aim of this review is to summarize the evidence that we and others have accumulated in support of this hypothesis.
Single-Domain Antibodies for the Detection of SARS-CoV-2 Nucleocapsid Protein (2021)

The goal of this work was to develop recombinantly expressed variable domains derived from camelid heavy-chain antibodies known as single-domain antibodies (sdAbs) directed against the SARS-CoV-2 nucleocapsid protein for incorporation into detection assays. To achieve this, a llama was immunized using a recombinant SARS-CoV-2 nucleocapsid protein and an immune phage-display library of variable domains was developed. The sdAbs selected from this library segregated into five distinct sequence families. Three of these families bind to unique epitopes with high affinity, low nM to sub-nM <i>K</i><sub>D</sub>, as determined by surface plasmon resonance. To further enhance the utility of these sdAbs for the detection of nucleocapsid protein, homobivalent and heterobivalent genetic fusion constructs of the three high-affinity sdAbs were prepared. The effectiveness of the sdAbs for the detection of nucleocapsid protein was evaluated using MagPlex fluid array assays, a multiplexed immunoassay on color-coded magnetic microspheres. Using the optimal bivalent pair, one immobilized on the microsphere and the other serving as the biotinylated recognition reagent, a detection limit as low as 50 pg/mL of recombinant nucleocapsid and of killed virus down to 1.28 × 10<sup>3</sup> pfu/mL was achieved. The sdAbs described here represent immune reagents that can be tailored to be optimized for a number of detection platforms and may one day aid in the detection of SARS-CoV-2 to assist in controlling the current pandemic.
Application of Stem Cells for Articular Cartilage Regeneration (2009)

Articular cartilage is a highly organized tissue lacking self-regeneration capacity upon lesion. Current surgical intervention by application of in vitro-expanded autologous chondrocytes transplantation procedure is associated with several disadvantages, including donor-site morbidity and inferior fibrocartilage formation at the defect site. However, recent advancements in tissue engineering have provided notable strategies for stem cell-based therapies and articular cartilage tissue engineering. In this review, we discuss the current strategies to engineer cartilage tissues from adult stem cells and human embryonic stem cell-derived cells. The characteristics of adult stem cells, the microenvironmental control of cell fate determination, and the limitation imposed by the intrinsic nature of stem cells are discussed. The strategy to commit the stem cells for functional cartilage tissues in vivo is also discussed.
A versatile 700-1200-V IC process for analog and switching applications (1991)

An IC process with a wide range of devices up to 1200 V is described. In addition to low-voltage bipolars and CMOS and 230-V VDMOS it provides 700-V high-side LDMOS, HV-PMOS (EPMOS) and low-voltage circuitry, low-side 1200-V LDMOS and 700-V LIGBT (lateral insulated-gate bipolar transistor), as well as 700-V interconnection. These features have been realized by using a substrate of higher resistance in a 250-300-V IC process and by adaptation in the Resurf structure for lateral DMOS. Application examples for flyback and half-bridge power conversion and as a power-bridge driver are given.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Expression of Gonadotropin-Releasing Hormone and Prothymosin-α Messenger Ribonucleic Acid in the Ovary* (1990)

GnRH exerts paradoxical effects on ovarian cells through specific receptors. Based on observed direct effects of GnRH and its antagonists on ovarian functions, the presence of endogenous ovarian GnRH-like peptide(s) has been postulated. In an attempt to detect the ovarian expression of GnRH or related genes at the RNA level, we used the reverse transcription-polymerase chain reaction (RT-PCR) to amplify GnRH mRNA levels. Total RNA from rat ovaries was converted to first strand cDNA using reverse transcriptase and amplified in PCR using a pair of primers complementary to the rat GnRH cDNA. The DNA products obtained were subcloned into plasmid vectors, and their sequences were determined. The most prominent PCR product of 462 basepairs (bp) was unexpectedly identified as a fragment of prothymosin-alpha cDNA previously found in the spleen. This cDNA was obtained because of an identical 10 bp match with the 3' end of one of the GnRH primers. Northern blot analyses using the cloned prothymosin-alpha cDNA as probe revealed the presence of mRNA for this factor in ovary, thymus, testis, placenta, and hypothalamus. RT-PCR amplification of hypothalamus and granulosa cell messages indicated the presence of a 244-bp product with a sequence identical to that of GnRH. To further confirm the presence of GnRH messages in the ovary, a second set of GnRH primers was used. PCR amplification of cDNA from hypothalamus, granulosa cells, and whole ovary yielded a 241-bp product identical to the authentic GnRH sequence based on analysis on both strands. In contrast, no PCR product was evident after amplification of thyroid cDNA. Our data demonstrated the expression of mRNA for GnRH and prothymosin-alpha in the ovary. Although the exact ovarian role of the immune hormone awaits further study, the detection of GnRH transcript in the ovary suggests potential intragonadal roles of this decapeptide.
Decoding hand kinematics from population responses in sensorimotor cortex during grasping (2019)

The hand, a complex effector comprising dozens of degrees of freedom of movement, endows us with the ability to flexibly, precisely, and effortlessly interact with objects. The neural signals associated with dexterous hand movements in primary motor cortex (M1) and somatosensory cortex (SC) have received comparatively less attention than have those that are associated with proximal limb control. To fill this gap, we trained three monkeys to grasp objects varying in size, shape and orientation while tracking their hand postures and recording single-unit activity from M1 and SC. We then decoded their hand kinematics across 30 joints from population activity in these areas. We found that we could accurately decode kinematics with a small number of neural signals and that performance was higher for decoding joint angles than joint angular velocities, in contrast to what has been found with proximal limb decoders. We conclude that cortical signals can be used for dexterous hand control in brain machine interface applications and that postural representations in SC may be exploited via intracortical stimulation to close the sensorimotor loop.
Signaling by vascular cell adhesion molecule‐1 (VCAM‐1) through VLA‐4 promotes CD3‐dependent T cell proliferation (1991)

Vascular cell adhesion molecule, VCAM-1, is an adhesion molecule expressed on activated endothelium thought to play a role in leukocyte migration to sites of inflammation. VCAM-1 adheres to leukocytes through the VLA-4 integrin. Recombinant soluble VCAM-1 (rsVCAM) and anti-CD3 mAb OKT3 were utilized to address the role of the VCAM-1/VLA-4 pathway in antigen-dependent T cell activation. Monocyte-depleted T cells proliferated upon exposure to co-immobilized OKT3 and rsVCAM but to neither alone. In contrast, an anti-VLA-4 mAb HP1/2 failed to co-activate with OKT3, despite the fact that both rsVCAM and HP1/2 support T cell adhesion comparably. These data indicate that adhesive function is not sufficient for co-stimulatory activity. They also reveal that VCAM-1 may play a role in regulating T cell immune responses as well as migration in vivo.
Polarization Pulling Induced by Raman Amplification in Telecommunication Optical Fibers (2009)

We exploit the polarization dependence of the Raman amplification to obtain a polarization pulling effect in telecommunication optical fibers. Experiments carried out with 1571-nm signal and copropagating high-power 1486-nm pump evidence the polarization pulling.
Recency-sensitive model of web page authority (2012)

Traditional link-based web ranking algorithms run on a single web snapshot without concern of the dynamics of web pages and links. In particular, the correlation of web pages freshness and their classic PageRank is negative (see [11]). For this reason, in recent years a number of authors introduce some algorithms of PageRank actualization. We introduce our new algorithm called Actual PageRank, which generalizes some previous approaches and therefore provides better capability for capturing the dynamics of the Web. To the best of our knowledge we are the first to conduct ranking evaluations of a fresh-aware variation of PageRank on a large data set. The results demonstrate that our method achieves more relevant and fresh results than both classic PageRank and its "fresh" modifications.
Essential Oils from Bolivia. VII. Myrtaceae:Myrcianthes osteomeloides(Rusby) McVaugh andMyrcianthes pseudomato(Legrand) McVaugh (2005)

Abstract The chemical composition of the essential oils of Myrcianthes osteomeloides and M. pseudomato was studied by GC and GC/MS. Myrcianthes osteomeloides oil contained 1,8-cineole (55.7%) as the major component followed by α-pinene (17.9%), α-terpineol (8.5%) and β-pinene (4.6%). We identified 1,8-cineole (24.4%), α-pinene (17.1%), linalool (11.7%), limonene (8.5%) and γ-terpinene (7.3%) as main constituents in M. pseudomato oil.
Retinal Vascular Imaging (2008)

The microcirculation is relatively inaccessible to direct visualization and investigation. Recent methods have been developed which use advanced retinal photographic imaging techniques and computer-assisted image analysis to characterize, measure and quantify subtle variations and abnormalities in the retinal vasculature. These quantitative and qualitative assessments demonstrate a close association of retinal vascular signs to both clinical and subclinical cerebrovascular, cardiovascular and metabolic outcomes. Retinal vascular imaging may thus offer potential as a noninvasive research tool to probe the role and pathophysiology of the microvasculature, and as a cardiovascular risk prediction tool. Key areas where retinal vascular imaging has contributed to increased understanding of microvascular pathology and major areas of current and new research are discussed in this review.
RETINAL EVALUATION OF PATIENTS ON CHRONIC AMIODARONE THERAPY (2003)

No significant adverse retinal funduscopic changes or electrophysiologic effects could be correlated with amiodarone exposure in this small series of patients. Routine electrophysiologic and funduscopic screening of patients receiving amiodarone does not seem warranted, although future prospective controlled studies may be required to exclude the possibility of progressive abnormalities in patients with preexisting age-related macular degeneration.
157 Pathogenesis of Epstein-Barr Virus-driven lymphomas of HIV+ patients (2014)

Human Immunodeficiency Virus (HIV)+ patients have an increased risk to develop lymphomas, including a significant fraction of histotypes associated with Epstein-Barr Virus (EBV) infection. Although restoration of EBV-specific T-cell function induced by HAART has led to a decreased incidence of the more immunogenic EBV-associated lymphomas, such as immunoblastic and primary central nervous system lymphomas, other EBV+ histotypes are still prevalent in the HAART era, particularly Hodgkin’s lymphoma. Therefore, factors other than HIV-induced immune suppression are probably required for the development of EBV-related lymphomas in this setting. Particular attention is being given to the identification of microenvironmental stimuli able to up-regulate critical EBV latency proteins or to induce/enhance EBV replication. In fact, recent evidence indicates that, although latency programs predominate in EBV-driven tumors, lytic EBV replication may also be of pathogenic relevance, at least in the early phases of cell transformation. This is particularly relevant for HIV-related lymphomagenesis since the underlying impairment of immune responses may favour uncontrolled activation of EBV lytic replication in latently-infected B lymphocytes. Available data indicate that local expression of distinct cytokines, including IL-4 and IL-13, may up-regulate the expression of the LMP-1 oncoprotein in B cells, thus favoring lymphomagenesis. In the search of microenvironmental factors that may promote the development of EBV-driven lymphomas in HIV+ patients, we obtained evidence supporting a pathogenic role for HIV matrix protein p17, which accumulates in lymphoid tissues of HIV+ individuals, even during HAART. Our findings support a direct contribution of HIV p17 to the development of EBV-driven lymphomagenesis and may provide the rationale for new strategies of clinical intervention in this setting.
Theoretical Studies of the Strengths of Matrix/Second-Phase-Particle Interfaces (1993)

Abstract : We continue to make excellent progress towards our goal to theoretically model accurately and understand the properties of interfaces between grains or particles in general.
The growth of Nd: YAG single crystals (2002)

Y3Al5O12 doped with 0.8%wt.Nd (Nd:YAG) single crystals were grown by the Czochralski technique under an argon atmosphere. The conditions for growing the Nd:YAG single crystals were calculated by using a combination of Reynolds and Grashof numbers. The critical crystal diameter and the critical rate of rotation were calculated from the hydrodynamics of the melt. The crystal diameter Dc=1.5 cm remained constant during the crystal growth while the critical rate of rotation changed from ?c=38 rpm after necking to ?c=13 rpm at the end of the crystal. The value of the rate of crystal growth was experimentally found to be 0.8?1.0 mm/h. According to our previous experiments, it was confirmed that 20 min exposure to conc. H3PO4 at 603 K was suitable for chemical polishing. Also, one-hour exposure to conc. H3PO4 at 493 K was found to be suitable for etching. The lattice parameter a=1.201 (1) nm was determined by X-ray powder diffraction. The obtained results are discussed and compared with published data.
93Nb NMR study of the charge density wave state in NbSe2 (2009)

(93)Nb NMR studies were carried out for a single crystal of NbSe(2) at 73.328 MHz in the temperature range 9-300 K to investigate the normal and charge density wave (CDW) states. Detailed analysis of the NMR line shape of the central transition using a classical incommensurate model reveals the change in the conduction electron spin dynamics from above T(CDW). An increase of the Knight shift below T(CDW) reflects modification to the uniform part of the conduction electron density of states. As suggested theoretically, the Knight shift distribution is found to be directly proportional to the square of the amplitude of the CDW. The results further indicate an incommensurate CDW state in 2H-NbSe(2). Analysis of the NMR spectra using the McMillan incommensurate model suggests a large value of the discommensuration parameter (γ) which is almost temperature independent, in contrast to the much smaller value previously reported in the case of 2H-TaSe(2).