gebhart/patrepeval huggingface dataset:
Clinical and immunological factors that distinguish COVID-19 from pandemic influenza A(H1N1) (2020)

Abstract The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is a global health threat with the potential to cause severe disease manifestations in the lungs. Although clinical descriptions of COVID-19 are currently available, the factors distinguishing SARS-CoV-2 from other respiratory viruses are unknown. Here, we compared the clinical, histopathological, and immunological characteristics of patients with COVID-19 and pandemic influenza A(H1N1). We observed a higher frequency of respiratory symptoms, increased tissue injury markers, a histological pattern of alveolar pneumonia, and higher levels of IL-1RA, TNF-α, CCL3, G-CSF, APRIL, sTNF-R1, sTNF-R2, sCD30, and sCD163 in influenza patients. Conversely, dry cough, gastrointestinal symptoms, interstitial lung pathology, increased Th1 (IL-12, IFN-γ) and Th2 (IL-4, IL-5, IL-10, IL-13) cytokine levels, along with IL-1β, IL-6, CCL11, VEGF, TWEAK, TSLP, MMP-1, and MMP-3, were observed in COVID-19 cases. We demonstrated the diagnostic potential of some clinical and immune factors to differentiate COVID-19 from pandemic influenza A(H1N1). Our data suggest that SARS-CoV-2 induces a dysbalanced polyfunctional inflammatory response that is different from the immune response against influenza. These findings might be relevant for the upcoming 2020-2021 influenza season, which is projected to be historically unique due to its convergence with COVID-19.
Reactions of Coordinated Ligands. VI. Metal Ion Control in the Synthesis of Planar Nickel(II) Complexes of α-Diketo-bis-mercaptoimines (1964)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReactions of Coordinated Ligands. VI. Metal Ion Control in the Synthesis of Planar Nickel(II) Complexes of α-Diketo-bis-mercaptoiminesMajor C. Thompson and Daryle H. BuschCite this: J. Am. Chem. Soc. 1964, 86, 2, 213–217Publication Date (Print):January 1, 1964Publication History Published online1 May 2002Published inissue 1 January 1964https://pubs.acs.org/doi/10.1021/ja01056a021https://doi.org/10.1021/ja01056a021research-articleACS PublicationsRequest reuse permissionsArticle Views943Altmetric-Citations102LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Erratum: “Tailorable, visible light emission from silicon nanocrystals” [Appl. Phys. Lett.74, 3164 (1999)] (2008)

First Page
Tunable optical delay with on-chip analogue to EIT (2006)

We measure group delay in a silicon based coupled-resonator device with transmission properties analogous to those of electromagnetically-induced-transparency system. We demonstrate thermal tuning of the group delay in this device.
Miscibility and Mechanical Properties of Poly(ether imide)/Liquid Crystalline Poly(ester imide) Blends (1994)

Abstract As a part of continuous study to search for the high performance in situ composite, this study examines the miscibility of liquid crystalline poly(ester imide) (PEsI) with poly(ether imide) (PEI) and its effect on the mechanical properties and the morphology of the blends of these polymers. Liquid crystalline polymers (LCPs) were synthesized from trimellitic anhydride and α,ω-diaminoalkane with 8, 10, 12 methylene groups. Thermal condensation of these diacids with 4,4′-diacetoxybiphenyl yielded the corresponding imides of thermotropic homopolyesters. Optical polarized micrographs show that the synthesized poly(ester imides) have the smectic structure. Partial miscibility was observed from the shift of the glass transition temperature determined by differential scanning calorimetry. Increasing concentration of the liquid crystalline PEsI in the PEI/PEsI blends shifted the glass transition temperature of the PEI phase to a lower temperature. Mechanical properties of the PEI/PEsI blends were changed with the number of methylene units in PEsI. Morphologies of the partially miscible system were found to be quite different from those of an immiscible system. Strong adhesion between the matrix (PEI) and dispersed phase (LCP) was observed, but fine fibril formation was not possible due to the absence of smectic-nematic transition.
Synthesis of Cadmium Arsenide Quantum Dots Luminescent in the Infrared (2011)

We present the synthesis of Cd(3)As(2) colloidal quantum dots luminescent from 530 to 2000 nm. Previous reports on quantum dots emitting in the infrared are primarily limited to the lead chalcogenides and indium arsenide. This work expands the availability of high quality infrared emitters.
Phase II trial of cetuximab in the treatment of persistent or recurrent squamous or non-squamous cell carcinoma of the cervix: A Gynecologic Oncology Group study (2020)

The Gynecologic Oncology Group (GOG) conducted a phase II trial to assess the efficacy and tolerability of the anti-EGFR antibody cetuximab, in persistent or recurrent carcinoma of the cervix.
Optimized gain control for single-frequency relaying with loop interference (2009)

This letter derives new gain control schemes for an amplify-and-forward single-frequency relay link in which loop interference from the relay transmit antenna to the relay receive antenna has to be tolerated. The proposed gain control schemes take into account the effect of residual loop interference that remains after imperfect loop interference cancellation. As a result of our gain control strategy, the signal-to-interference and noise ratio can be maximized while, at the same time, transmit power is decreased. Finally, we evaluate system performance by deriving closed-form outage probability expressions for the gain control schemes.
Triboluminescence of inorganic sulfates (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTriboluminescence of inorganic sulfatesB. P. Chandra and Jeffrey I. ZinkCite this: Inorg. Chem. 1980, 19, 10, 3098–3102Publication Date (Print):October 1, 1980Publication History Published online1 May 2002Published inissue 1 October 1980https://pubs.acs.org/doi/10.1021/ic50212a054https://doi.org/10.1021/ic50212a054research-articleACS PublicationsRequest reuse permissionsArticle Views295Altmetric-Citations61LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Malfunction of digital circuits caused by noise induced in breaking electric contacts (1989)

Abstract The malfunction of a digital circuit has been investigated from the viewpoint of the IC as its constituent. However, little has been reported from the viewpoint of electrical contact which is one of the principal causes of the malfunction. In the research reported here, simple automatic measurement equipment has been developed which counts the malfunctions of a digital circuit. Measurement has been done with this equipment under various circuit conditions. As a result, it was found that malfunctions of digital circuits not only increase with the load circuit current, but may decrease when the circuit current exceeds a certain value depending on the parallel capacitance between contacts. As the parallel capacitance between contacts increases, the region in which malfunctions are likely to occur shifts toward a larger current side. It was found that these elements are related closely to the region of showering arc generation which is one of the discharge modes at the time electrical contacts open. Also, since the parallel capacitance between contacts is larger, the 0 percent malfunction rate is approached while the wiring spacing between the inductive and induced wires is closer. For this characteristic, the frequency spectrum of the dielectric breakdown region of the showering arc voltage waveform has been derived.
Introduction (2022)

Subscriptions enhanced the economic success of the Sunday paper by helping to produce expert reading subjects. In the 1880s, new forms of journalism organized readers' mass engagement through fundraising for charitable and civic causes. The reformist impulse spawned undercover reports by women journalists, while techniques for engagement became popularity contests and guessing games. Both were key features of Sunday papers. New forms of newspaper reading such as these contests and games, complete with prizes and giveaways, which were instrumental in coordinating readers' sense of connection to wider cultural events. In New York, The Morning Journal and The Recorder launched novel forms of Sunday art supplements. The promotional tactic was borrowed from trade-card advertising to facilitate brand loyalty, a simple technology shaping readers into consumers. Collecting series of supplements and clipping coupons encouraged readers not to treat Sunday papers as disposable, but instead parts of cultural and consumer life that could gain value if saved. Clipping, amassing and mailing in coupons for art supplements transformed newspaper subscriptions into social relations with all variety of mass leisure and consumption. Sunday supplements demonstrated how daily newspapers were incomplete. Sunday papers extended the work of daily newspapers into new domains of modern life.
Fluid motion produced by ultrasonic Lamb waves (2002)

Fluid motion induced by traveling flexural waves in 4- mu m-thick membranes was observed using 2.5- mu m-diameter polystyrene spheres in water to make their fluid motion visible. Visual observation of the spheres indicates that their velocity is in the direction of wave propagation and is proportional to the square of the acoustic amplitude. The maximum speed is 130 mu m/s for an RF drive voltage of 7.1 V/sub rms/ at 3.5 MHz; the wavelength is 100 mu m. Sphere motion has been observed in regions without acoustic waves, suggesting fluid recirculation. Standing Lamb waves, which can be seen visually with a phase-contrast microscope, are found to trap particles, including bacteria located in a drop of water in contact with the membrane. A first-order model of Lamb-wave micropumping is based on acoustic streaming theory. Possible applications include temperature redistribution in ICs and miniature chemical processing systems.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Unique Process and Tool Provides Better Acid Stimulation and Better Production Results (2012)

Abstract There are many ways to stimulate an unlined openhole horizontal well using acid. The simplest way is to just pump acid into the well (i.e., bullhead) without placement control. However, this can often be ineffective. Although still used, such approaches can create massive enlargements at the entry point or high injectivity area, thus causing ineffective treatments and re-entry issues. Wellbore collapse often follows. The use of coiled tubing (CT) as a "pin-point" delivery method is therefore preferred. Using CT allows dispersal of the acid either uniformly or intermittently along the lateral, as desired. CT also allows acid washing to be performed, which is another common process that can improve stimulation without much additional expense to the operator. Using a jetting tool with many jets, acid can be sprayed onto the wellbore wall, and the active agitation caused by the acid-wash process increases the chemical reactivity of the acid at the desired locations. Another beneficial approach of using CT is the hydrajet assisted acid fracturing (HJAAF) method. With focused jetting of acid at much higher pressures, the process initiates microfractures in the wellbore walls. When etched with acid, this approach effectively bypasses near-wellbore (NWB) damage much deeper than common washes, thus providing much better results. Further modification of the process by exerting high annular pressures offers the capability of delivering medium to large fractures. This paper discusses two HJAAF processes uniquely combined into one process used in two large horizontal wells. Because of the large dimension of the inner diameter (ID) of the wells combined with the small production tubing the tool must pass through, the implementation had to be further improved by using a unique jetting mechanism, which positioned the jet nozzles closer to the target. Actual results of such stimulations are presented.
Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia (2017)

Borderline personality disorder (BOR) is determined by environmental and genetic factors, and characterized by affective instability and impulsivity, diagnostic symptoms also observed in manic phases of bipolar disorder (BIP). Up to 20% of BIP patients show comorbidity with BOR. This report describes the first case-control genome-wide association study (GWAS) of BOR, performed in one of the largest BOR patient samples worldwide. The focus of our analysis was (i) to detect genes and gene sets involved in BOR and (ii) to investigate the genetic overlap with BIP. As there is considerable genetic overlap between BIP, major depression (MDD) and schizophrenia (SCZ) and a high comorbidity of BOR and MDD, we also analyzed the genetic overlap of BOR with SCZ and MDD. GWAS, gene-based tests and gene-set analyses were performed in 998 BOR patients and 1545 controls. Linkage disequilibrium score regression was used to detect the genetic overlap between BOR and these disorders. Single marker analysis revealed no significant association after correction for multiple testing. Gene-based analysis yielded two significant genes: DPYD (P=4.42 × 10<sup>-7</sup>) and PKP4 (P=8.67 × 10<sup>-7</sup>); and gene-set analysis yielded a significant finding for exocytosis (GO:0006887, P<sub>FDR</sub>=0.019; FDR, false discovery rate). Prior studies have implicated DPYD, PKP4 and exocytosis in BIP and SCZ. The most notable finding of the present study was the genetic overlap of BOR with BIP (r<sub>g</sub>=0.28 [P=2.99 × 10<sup>-3</sup>]), SCZ (r<sub>g</sub>=0.34 [P=4.37 × 10<sup>-5</sup>]) and MDD (r<sub>g</sub>=0.57 [P=1.04 × 10<sup>-3</sup>]). We believe our study is the first to demonstrate that BOR overlaps with BIP, MDD and SCZ on the genetic level. Whether this is confined to transdiagnostic clinical symptoms should be examined in future studies.
Cross-path inference attacks on multipath TCP (2013)

Multipath TCP (MPTCP) allows the concurrent use of multiple paths between two end points, and as such holds great promise for improving application performance. However, in this paper, we report a newly discovered class of attacks on MPTCP that may jeopardize and hamper its wide-scale adoption. The attacks stem from the interdependence between the multiple subflows in an MPTCP connection. MPTCP congestion control algorithms are designed to achieve resource pooling and fairness with single-path TCP users at shared bottlenecks. Therefore, multiple MPTCP subflows are inherently coupled with each other, resulting in potential side-channels that can be exploited to infer cross-path properties. In particular, an ISP monitoring one or more paths used by an MPTCP connection can infer sensitive and proprietary information (e.g., level of network congestion, end-to-end TCP throughput, packet loss, network delay) about its competitors. Since the side-channel information enabled by the coupling among the subflows in an MPTCP connection results directly from the design goals of MPTCP congestion control algorithms, it is not obvious how to circumvent this attack easily. We believe our findings provide insights that can be used to guide future security-related research on MPTCP and other similar multipath extensions.
Liberação de componentes do extrato de Casearia sylvestris Swartz empregando membranas de látex natural como suporte (2015)

Made available in DSpace on 2018-12-11T17:24:24Z (GMT). No. of bitstreams: 0&#13;\n Previous issue date: 2014-01-01
Two Point Minimum Cost Path Approach for CTA Coronary Centerline Extraction (2008)

In this work a minimum cost path approach is adopted to extract coronary artery centerlines from CTA data. The algorithm depends on the manual definition of the start and end point of the vessel. The cost image used in the minimal cost path approach is based on a vesselness measure and a smooth window function on intensity. In the majority of the cases the method was able to extract the centerlines successfully (overlap &gt; 90%). Accuracy of the method is around two times the voxelsize of the datasets. To conclude, minimum cost path approaches have potential for coronary artery centerline extraction, but improvements, especially regarding the accuracy of the method, still need investigations.
Streamlined Processes for the Synthesis of a Farnesyl Transferase Inhibitor Drug Candidate (2004)

As part of a fast-paced oncology program, quinolinone 1 was discovered and developed as a potent inhibitor of farnesyl transferase for the treatment of cancer. The initial synthesis, which suffered from a lengthy linear sequence and a late-stage chromatographic resolution, was deemed not amenable to large-scale production. While investigating alternate routes to address these issues, the original synthesis was successively improved and streamlined. This enabled route supplied the timely production of drug substance required to support early toxicological and clinical studies. Several iterations of the process were made, and as a result of these improvements, an efficient four-step sequence was developed for the synthesis of quinolinone d-tartrate 2 starting from readily available outsourced intermediate 5 in 26% overall yield, including a classical resolution. The key features of the synthesis include a Castro−Stevens coupling, an imidazole Grignard addition, and a concomitant classical resolution/final salt formation with d-(−)-tartaric acid.
Single-cell genome and metatranscriptome sequencing reveal metabolic interactions of an alkane-degrading methanogenic community (2013)

Microbial interactions have a key role in global geochemical cycles. Although we possess significant knowledge about the general biochemical processes occurring in microbial communities, we are often unable to decipher key functions of individual microorganisms within the environment in part owing to the inability to cultivate or study them in isolation. Here, we circumvent this shortcoming through the use of single-cell genome sequencing and a novel low-input metatranscriptomics protocol to reveal the intricate metabolic capabilities and microbial interactions of an alkane-degrading methanogenic community. This methanogenic consortium oxidizes saturated hydrocarbons under anoxic conditions through a thus-far-uncharacterized biochemical process. The genome sequence of a dominant bacterial member of this community, belonging to the genus Smithella, was sequenced and served as the basis for subsequent analysis through metabolic reconstruction. Metatranscriptomic data generated from less than 500 pg of mRNA highlighted metabolically active genes during anaerobic alkane oxidation in comparison with growth on fatty acids. These data sets suggest that Smithella is not activating hexadecane by fumarate addition. Differential expression assisted in the identification of hypothetical proteins with no known homology that may be involved in hexadecane activation. Additionally, the combination of 16S rDNA sequence and metatranscriptomic data enabled the study of other prevalent organisms within the consortium and their interactions with Smithella, thus yielding a comprehensive characterization of individual constituents at the genome scale during methanogenic alkane oxidation.
Racial differences and determinants of macular thickness profiles in multiethnic Asian population: the Singapore Epidemiology of Eye Diseases Study (2018)

There are interethnic differences in MT profile among Asians, particularly between Chinese and Indians. Ocular and systemic factors affect MT measurements as well. This Asian-specific information may be incorporated into existing clinical interpretation of macular OCT scans to aid in improving the diagnostic and monitoring accuracy of macular diseases among Asians.
PRETREATMENT OF PHOSPHORUS PLANT PROCESS WASTEWATER CONTAINING ELEVATED LEVELS OF PHOSPHITE, HYPOPHOSPHITE, CYANIDE, AND HEAVY METALS (2003)

PRETREATMENT OF PHOSPHORUS PLANT PROCESS WASTEWATER CONTAINING ELEVATED LEVELS OF PHOSPHITE, HYPOPHOSPHITE, CYANIDE, AND HEAVY METALSAlternatives have been evaluated for the management of phosphorus plant wastewater stored in large surface impoundments. The wastewater contains total phosphorus and ortho-phosphate-P concentrations of 4000 and 2000 mg/L, respectively, the difference of which is primarily composed of phosphite and hypophosphite. The wastewater also contains significant levels of fluoride and zinc and lower levels...Author(s)Charles B. BottJohn H. KoonJay R. BrummerSourceProceedings of the Water Environment FederationSubjectSession 5 Pretreatment/Pollution PreventionDocument typeConference PaperPublisherWater Environment FederationPrint publication date Jan, 2003ISSN1938-6478SICI1938-6478(20030101)2003:2L.232;1-DOI10.2175/193864703784343857Volume / Issue2003 / 2Content sourceWEF EventFirst / last page(s)232 - 243Copyright2003Word count165
Effects of Procainamide and Sotalol on Restitution Properties, Dispersion of Refractoriness, and Ventricular Fibrillation Activation Patterns in Pigs (2008)

Procainamide and sotalol combined have greater beneficial effects on restitution properties, dispersion of refractoriness, and the complexity of VF than either drug alone compared with baseline.