gebhart/patrepeval huggingface dataset:
Hybrid modeling and control of a multibody magnetic actuator for automotive applications (2007)

This paper investigates model predictive control (MPC) techniques based on hybrid models for a multi-mass magnetic actuator. The actuator has four operating modes depending on the mutual interaction of two moving masses and is modeled as a hybrid dynamical system. The control law optimizes a performance index and enforces several types of constraints: soft-landing during collisions to reduce mechanical wear, current limits and consequent position-dependent nonlinear bounds on the available magnetic force, and restrictions on the positions of the moving masses. Two different approaches are considered: (i) a hybrid MPC design based on the full two- mass model, and (ii) a switched MPC control design, which switches between two simpler hybrid MPC controllers, one for the case in which the masses are moving in contact, and the other case where the masses are decoupled, commanded by a simple switching logic. Simulation results and performance comparisons of the two control schemes are discussed.
Effects of Sex Steroids and Growth Factors on Migration and Invasion of Endoraetrial Adenocarcinoma SNG‐M Cells in vitro (1996)

Biological effects of sex steroids (estradiol-17beta, E2; progesterone, P; medroxyprogesterone acetate, MPA; Danazol, DZ) and growth factors (epidermal growth factor, EGF; transforming growth factor, TGF-alpha,beta) on migration and invasion of endometrial adenocarcinoma SNG-M cells were investigated by haptotactic migration and haptoinvasion assay. The enzymatic degradation of the extracellular matrix by tumor cells was also examined. Tumor cell migration along a gradient of substratum-bound fibronectin was inhibited by 0.1-10 microM MPA and DZ, but promoted by 0.1-10 nM EGF and TGF-alpha in a concentration-dependent manner. E2, P and TGF-beta did not have any effect on the motility of tumor cells. These effects were also confirmed by wound assay. The invasive activity of SNG-M cells into reconstituted basement membrane (Matrigel) was inhibited by the presence of 0.1-10 microM MPA and DZ, but promoted by 0.1-10 nM EGF and TGF-alpha in a concentration-dependent manner. E2, P and TGF-beta did not have any effect on tumor cell invasion. The zymography of tumor-conditioned medium showed that the treatment of SNG-M cells with EGF and TGF-alpha resulted in the increase of the 68, 72 and 92 kDa type IV collagenases (matrix metalloproteinase, MMP-2 and 9). Sex steroids and TGF-beta did not have significant effects on MMP-2 and 9. Stromelysin (MMP-3), also secreted by SNG-M cells, was not affected by sex steroids and growth factors. These results suggest that EGF and TGF-alpha act as positive regulators on the invasion process of endometrial adenocarcinoma cells, which may partly be associated with the induction of type IV collagenase secretion by tumor cells. The inhibitory effects of MPA and DZ on tumor cell invasion may depend at least partly on their inhibitory action on the motility of tumor cells.
Tuning of electrical and optical properties of organic LEDs using combinatorial device fabrication (2002)

Abstract— The capabilities of combinatorial methods are presented in order to get a detailed understanding of the electrical and optical properties of organic light‐emitting devices (OLEDs), to optimize their performance, and to provide reliable data for device modeling. We show results on multilayer OLEDs ranging from the conventional copper‐phthalocyanine (CuPc)/N,N′di‐(naphtalene‐1‐yl)‐N,N′‐diphenyl‐benzidine (NPB) and tris‐(8‐hydroxy‐quinolinato)aluminum (Alq) tri‐layer device to double‐doped deep‐red‐emitting OLEDs.
Multi-cohort analysis of host immune response identifies conserved protective and detrimental modules associated with severity irrespective of virus (2020)

Abstract SARS-CoV-2 pandemic, the fourth pandemic of the decade, has underscored gaps in global pandemic preparedness and the need for generalizable tests to avert overwhelming healthcare systems worldwide, irrespective of a virus. We integrated 4,780 blood transcriptome profiles from patients infected with one of 16 viruses across 34 independent cohorts from 18 countries, and 71 scRNA-seq profiles of 264,224 immune cells across three independent cohorts. We found a myeloid cell-dominated conserved host response associated with severity. It showed increased hematopoiesis, myelopoiesis, and myeloid-derived suppressor cells with increased severity. We identified four gene modules that delineate distinct trajectories associated with mild and severe outcomes, and show the interferon response was decoupled from protective host response during severe viral infection. These modules distinguished non-severe from severe viral infection with clinically useful accuracy. Together, our findings provide insights into immune response dynamics during viral infection, and identify factors that may influence patient outcomes.
Plasmonic Photopatterning: High‐Resolution and High‐Throughput Plasmonic Photopatterning of Complex Molecular Orientations in Liquid Crystals (Adv. Mater. 12/2016) (2016)

On page 2353, Q.-H. Wei and co-workers present a plasmonic photopatterning technique for aligning liquid-crystal (LC) molecules into arbitrarily complex patterns. By encoding target molecular orientations in plasmonic metamasks, this technique enables repeatable and scalable alignments of LCs with high spatial resolution and high throughput, which promises applications in the fabrication of various LC devices.
Catalytic reforming of methane to syngas in an oxygen-permeative membrane reactor (2011)

For fuel cell applications, partial oxidative reforming of methane to syngas, hydrogen and carbon monoxide, was performed via a dense oxygen-permeative ceramic membrane composed by both ionic and electronic conductive materials. The modification of Ni-based catalyst by noble metals was investigated to increase oxygen permeation flux and decrease carbon deposition during reforming reaction. The role of each component in catalyst was also discussed.
Genomic alterations in distal bile duct carcinoma by comparative genomic hybridization and karyotype analysis (1999)

We report genomic abnormalities identified in 14 human primary common bile duct carcinomas analyzed by cytogenetics or comparative genomic hybridization, or both. Combining the results of the two methods of analysis, 11 chromosomal arms were observed to be gained in whole or in part, and 9 chromosomal arms were lost in whole or in part in at least four tumors each. The most frequently lost chromosomal regions were, in decreasing order: 18q (eight tumors); 6q and 10p (seven tumors each); 8p, 12q, and 17p (six tumors each); and 7q, 12p, and 22q (four tumors each). The most frequently gained regions were 8q and 20q (six tumors each); 12p, 17q, and Xp (five tumors each); and 2q, 6p, 7p, 11q, 13q, and 19q (four tumors each). These results are similar to those we have previously reported in pancreatic cancer and suggest that carcinomas of the common bile duct and pancreas share a number of genetic changes.
Analysis and Control of Protein Crystallization Using Short Peptide Tags That Change Solubility without Affecting Structure, Thermal Stability, and Function (2015)

Short peptide tags attached to recombinant proteins are emerging as an important tool for biochemical research. Here, we report the effects of 10 Solubilization Controlling Peptide (SCP) tags on crystallization behavior of a bovine pancreatic trypsin inhibitor (BPTI) variant. The tags did not affect structure, thermodynamics, and activities of BPTI. Moreover, eight of the tagged variants crystallized under the same condition, and six of them diffracted at high resolution. All variants with long-term solubility (LS) between 1 and 6 mg/mL produced crystals that diffracted well, while variants with LS < 1 and >6 mg/mL did not crystallize, produced poorly diffracting crystals, or crystallized under a different condition. The only exception was a glutamine tagged variant, which had an LS of 5 mg/mL, but fast aggregation kinetics, and produced mere needles unsuitable for further analysis. Crystal structures indicated that most tags were largely invisible, indicating high flexibility, without having interactions with nearby residues. Therefore, short peptides, introducing a mere 5–7 residue elongation, could provide a useful technology for tuning protein solubility without affecting its other properties and hence for overcoming problems associated with excessively low or high solubility, such as in crystallization.
Sequence Learning and Consolidation on Loihi using On-chip Plasticity (2022)

In this work we develop a model of predictive learning on neuromorphic hardware. Our model uses the on-chip plasticity capabilities of the Loihi chip to remember observed sequences of events and use this memory to generate predictions of future events in real time. Given the locality constraints of on-chip plasticity rules, generating predictions without interfering with the ongoing learning process is nontrivial. We address this challenge with a memory consolidation approach inspired by hippocampal replay. Sequence memory is stored in an initial memory module using spike-timing dependent plasticity. Later, during an offline period, memories are consolidated into a distinct prediction module. This second module is then able to represent predicted future events without interfering with the activity, and plasticity, in the first module, enabling online comparison between predictions and ground-truth observations. Our model serves as a proof-of-concept that online predictive learning models can be deployed on neuromorphic hardware with on-chip plasticity.
Using Drive Rods in Induction Cells to Reduce the Beam Break Up Instability (2018)

The beam breakup instability is an effect that must be heavily suppressed for optimum operation of high current induction accelerators. The RF modes generated inside the induction cells can deflect or degrade subsequent beam traversing the cell. Significant effort has been invested in minimizing the effect over several decades. One mechanism that is known to reduce the transverse impedance, the main observable experimentally which directly relates to the BBU amplitude, is to introduce ferrites to absorb the fields. Another, less investigated mechanism, is to disturb the modes symmetry by inserting the drive rods at the proper locations in the cell. This paper will show that the drive rods can dramatically reduce the transverse impedance and will show that simulations are maturing towards predicting this effect.
Endotypes of Chronic Rhinosinusitis; relationships to disease phenotypes, pathogenesis, clinical findings and treatment approaches. (2021)

Chronic rhinosinusitis (CRS) is a common clinical syndrome that produces significant morbidity and costs to our health system. The study of CRS has progressed from an era focused on phenotype to include endotype based information. Phenotypic classification has identified clinical heterogeneity in CRS based on endoscopically observed features such as presence of nasal polyps, presence of comorbid or systemic diseases and timing of disease onset. More recently, laboratory-based findings have established CRS endotype based upon specific mechanisms or molecular biomarkers. Understanding the basis of widespread heterogeneity in the manifestations of CRS is advanced by findings that the three main endotypes, Type 1, 2 and 3, orchestrate the expression of three distinct large sets of genes. The development and use of improved methods of endotyping disease in the clinic is ushering in an expansion of the use of biological therapies targeting Type 2 inflammation now and perhaps other inflammatory endotypes in the near future. The purpose of this review is to discuss the phenotypic and endotypic heterogeneity of CRS from the perspective of advancing the understanding of the pathogenesis and improvement of treatment approaches and outcomes.
Distributed Measurement of Bending-Induced Birefringence in Single-Mode Fibers with PA-OFDR (2018)

We demonstrate the distributed bending-induced birefringence measurement in single-mode fibers with high spatial resolution using a polarization-analyzing optical frequency domain reflectometer. The bending-induced birefringence coefficient of 5.499×10−10m2 is accurately obtained.
Self-Supervised Shape Alignment for Sports Field Registration (2022)

This paper presents an end-to-end self-supervised learning approach for cross-modality image registration and homography estimation, with a particular emphasis on registering sports field templates onto broadcast videos as a practical application. Rather then using any pairwise labelled data for training, we propose a self-supervised data mining method to train the registration network with a natural image and its edge map. Using an iterative estimation process controlled by a score regression network (SRN) to measure the registration error, the network can learn to estimate any homography transformation regardless of how misaligned the image and the template is. We further show the benefits of using pretrained weights to finetune the network for sports field calibration with few training data. We demonstrate the effectiveness of our proposed method by applying it to real-world sports broadcast videos where we achieve state-of-the-art results and real-time processing.
Design, optimization and characterization of a superdirective antenna array (2013)

This paper presents the design and the entire experimental characterization of a superdirective antenna array. The antenna system is composed of two closely spaced bow-tie monopoles fed by a power divider associated to a Matching Network (MN) and a Decoupling Network (DN). Given the high accuracy required for achieving superdirectivity in terms of amplitude and phase excitations, the radiating elements, the DN and the MN have been separately designed and experimentally characterized using a hybrid simulation/measurement method. Finally, the return loss and the 3D radiation patterns of the entire antenna system have been measured and compared with simulations. A 10dB directivity is achieved for this 0.13λ spaced antenna array, which validate the superdirectivity benefit and gives perspectives in terms of miniaturized high gain antenna systems for WIFI set-top box applications.
Kinetics of leukotriene A4 synthesis by 5-lipoxygenase from rat polymorphonuclear leukocytes (1987)

When arachidonic acid is added to lysates of rat polymorphonuclear leukocytes, it is oxidized to (5S)-hydroperoxy-6(E),8(Z),11(Z),14(Z)-eicosatetraenoic acid (5-HPETE). The 5-HPETE then partitions between reduction to the 5-hydroxyeicosanoid and conversion to leukotriene A4 (LTA4). Both steps in the formation of LTA4 are catalyzed by the enzyme 5-lipoxygenase. When [3H]arachidonic acid and unlabeled 5-HPETE were incubated together with 5-lipoxygenase, approximately 20% of the arachidonic acid oxidized at low enzyme concentrations was converted to LTA4 without reduction of the specific radioactivity of the LTA4 by the unlabeled 5-HPETE. A significant fraction of the [3H]-5-HPETE intermediate that is formed from arachidonic acid must therefore be converted directly to LTA4 without dissociation of the intermediate from the enzyme. This result predicts that even in the presence of high levels of peroxidase activity, which will trap any free 5-HPETE by reduction, the minimum efficiency of conversion of 5-HPETE to LTA4 will be approximately 20%, and this prediction was confirmed. 5-HPETE was found to be a competitive substrate relative to arachidonic acid, so that it is likely that the two substrates share a common active site.
Topological supramolecular network enabled high-conductivity, stretchable organic bioelectronics (2022)

Intrinsically stretchable bioelectronic devices based on soft and conducting organic materials have been regarded as the ideal interface for seamless and biocompatible integration with the human body. A remaining challenge is to combine high mechanical robustness with good electrical conduction, especially when patterned at small feature sizes. We develop a molecular engineering strategy based on a topological supramolecular network, which allows for the decoupling of competing effects from multiple molecular building blocks to meet complex requirements. We obtained simultaneously high conductivity and crack-onset strain in a physiological environment, with direct photopatternability down to the cellular scale. We further collected stable electromyography signals on soft and malleable octopus and performed localized neuromodulation down to single-nucleus precision for controlling organ-specific activities through the delicate brainstem.
Needle insertion modelling and simulation (2003)

A methodology for estimating the force distribution that occurs along a needle shaft during insertion is described. To validate the approach, an experimental system for measuring planar tissue deformation during needle insertions has been developed and is presented. The planar motion of a soft tissue phantom is measured during needle penetration and used in conjunction with a two dimensional linear elastostatic material model, discretised using the finite element method, to derive contact force information that is not directly measurable. This approach provides a method for quantifying the needle forces and soft tissue deformations that occur during general needle trajectories in multiple dimensions. A simulation algorithm that is based upon these results is also described.
A compact radiation pattern diversity antenna for WLAN applications (2003)

This paper proposes a novel planar antenna structure with a radiation pattern diversity. Such an antenna is designed for wireless indoor network applications and is particularly suitable for improving system performances in a multipath propagation environment. The new antenna structure is based on two tangential annular slot antennas etched on one side of a dielectric substrate and fed by electromagnetic coupling to microstrip feeding lines. This structure also incorporates an integrated switching function which allows control of the radiation pattern. Actually three radiation pattern configurations can be checked thanks to two PIN diodes.
Combating information overload in non-visual web access using context (2007)

Web sites are designed for graphical mode of interaction. Sighted users can visually segment Web pages and quickly identify relevant information. In contrast, visually-disabled individuals have to use screen readers to browse the Web. Screen readers process pages sequentially and read through everything, making Web browsing time-consuming and strenuous. The use of shortcut keys and searching offers some improvements, but the problem still remains. In this paper, we address this problem using the notion of context. When a user follows a link, we capture the context of the link, and use it to identify relevant information on the next page. The content of this page is rearranged, so that the relevant information is read out first. We conducted a series experiments to compare the performance of our prototype system with the state-of-the-art JAWS screen reader. Our results show that the use of context can potentially save browsing time as well as improve browsing experience of visually disabled individuals.
Analysis on the Characteristics of Rician Fading in Massive MIMO Systems (2015)

본 논문에서는 massive MIMO (Multiple-Input Multiple-Output) 시스템에서 발생하는 Rician 페이딩 특성을 분석한다. 이를 위해, 3차원 레이 트레이싱 시뮬레이터인 Wireless Insite를 이옹하여 도심 마이크로셀 환경에서의 massive MIMO 시스템의 도플러 확산(doppler spread)과 라이시안 K-factor(Rician K-factor) 특성을 비교 분석하였다. 4개의 안테나 소자로 선형 배열된 기존 MIMO 시스템과 128개의 안테나 소자로 선형 배열된 massive MIMO 시스템의 특성을 비교 분석한 결과, 128개 안테나 소자로 배열된 massive MIMO 시스템의 도플러 확산값이 기존 MIMO 시스템 보다 감소하고, Rician K-factor가 기존 MIMO 시스템에 보다 증가함을 확인하였다. 이를 통해 massive MIMO 시스템 디자인과 최적화 시에 필수적으로 고려해야 할 무선 채널 특성을 제시하였다.
Orbital angular momentum modes from vertical-cavity surface-emitting lasers (2016)

A computationally efficient theoretical approach is used to assess the performance of novel devices with directly emitting optical vortex modes.
Comparison of Ni/Au and Pd/Au ohmic contacts to p-GaN (2017)

This paper describes a comparative study of Ni/Au and Pd/Au ohmic contacts to p-GaN. Effects of annealing temperature and acceptor concentration on ohmic characteristics were investigated. It was found that both ohmic contacts exhibited a contact resistivity of less than 4×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-3</sup> Ωcm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> after 600 °C annealing. Moreover, fairly good ohmic behaviors were observed for Pd/Au even without annealing.
A Methodology to Measure Aerodynamic Forces on Cylinders in Channel Flow (2010)

While the measurement of drag and lift forces on a body in external flow is common practice, the same cannot be said for aerodynamic forces on bodies in internal flows. The inherent difficulty in making force measurements on a body in an internal channel flow is decoupling the body from the bounding walls. The methodology presented in this paper uses a technique to overcome this constraint to accurately measure two components of force on a single cylinder within a single row array, with an aspect ratio (height-to-diameter ratio) of 1. Experiments were conducted with air over a range of Reynolds numbers between 7500 and 35,000 and for three different spanwise pin spacings. Experimental results indicated an increase in cylinder drag with a reduction in spanwise pin spacing. The gas turbine and electronics industries use cylinders or pin fins in internal flow channels to increase heat transfer augmentation through high turbulence and increased surface area. The flow fields in these obstructed channels are difficult to predict, so these measurements can be used to directly compare with predicted drag and lift forces.
Occurrence of superoxide radical ion in crystalline calcium aluminate 12CaO.7Al2O3 prepared via solid-state reactions (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTOccurrence of superoxide radical ion in crystalline calcium aluminate 12CaO.7Al2O3 prepared via solid-state reactionsHideo Hosono and Yoshihiro AbeCite this: Inorg. Chem. 1987, 26, 8, 1192–1195Publication Date (Print):April 1, 1987Publication History Published online1 May 2002Published inissue 1 April 1987https://doi.org/10.1021/ic00255a003RIGHTS & PERMISSIONSArticle Views661Altmetric-Citations149LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (534 KB) Get e-Alerts Get e-Alerts