gebhart/patrepeval huggingface dataset:
Nitroxide-Mediated Free-Radical Polymerization of Styrene. Absence of the Gel Effect (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNitroxide-Mediated Free-Radical Polymerization of Styrene. Absence of the Gel EffectMarko D. Saban, Michael K. Georges, Richard P. N. Veregin, Gordon K. Hamer, and Peter M. KazmaierCite this: Macromolecules 1995, 28, 20, 7032–7034Publication Date (Print):September 1, 1995Publication History Published online1 May 2002Published inissue 1 September 1995https://pubs.acs.org/doi/10.1021/ma00124a049https://doi.org/10.1021/ma00124a049research-articleACS PublicationsRequest reuse permissionsArticle Views367Altmetric-Citations50LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Progressive conus medullaris lesions are suggestive of intravascular large B‐cell lymphoma (2023)

Spinal cord involvement in IVLBCL has a predominantly chronic progressive course that is exclusive to brain involvement. Conus medullaris lesions are suggestive of IVLBCL and are useful for early and accurate diagnosis and treatment.
Chirp of passively and actively mode-locked semiconductor lasers (1995)

The experimental observation of blue-chirped pulses for passive mode-locking and red-chirped pulses for active mode-locking is theoretically explained as a consequence of different α parameters in the gain and absorber section. The influence of nonlinear gain due to carrier heating is also discussed. The knowledge of the chirp is crucial for the optimization of passively mode-locked lasers for spectrally narrow emission or for the emission of linearly chirped pulses.
Chirally Homogeneous and Heterogeneous Dendritic Liquid Crystals (2013)

We have coupled methyl α-d-glucoside (G) and methyl α-d-mannoside (M) as the chiral structural variant moieties in the core and at the branching sites within dendritic scaffolds surrounded by 12 cyanobiphenyl mesogens (CB). Systematic studies of the influence of the chiral moieties on thermal and mesomorphic properties were carried out by positional permutation approach of the pyranose units G and M within the core and branching points. The mesomorphic properties of the chirally homogeneous dendrimers GG4/MM4 and the corresponding chirally heterogeneous dendritic homologues GM4/MG4 were investigated by differential scanning calorimetry (DSC) and polarized optical microscopy (POM). Remarkably, the thermal profile and the mesophase structure of the four dendrimers appear to be significantly independent of the nature of the central chiral core. The outer chirality at the periphery significantly dominates the liquid crystalline properties.
Proceedings of the 11th International Workshop on Health Text Mining and Information Analysis, LOUHI@EMNLP 2020, Online, November 20, 2020. (2020)

International audience
Optimal amortized regret in every interval (2014)

Abstract. Consider the classical problem of predicting the next bit in a sequence of bits. A standard performance measure is regret (loss in payoff) with respect to a set of experts. For example if we measure per-formance with respect to two constant experts one that always predicts 0’s and another that always predicts 1’s it is well known that one can get regret O( T) with respect to the best expert by using, say, the weighted majority algorithm [1]. But this algorithm does not provide performance guarantee in any interval. There are other algorithms (see [2,3,4]) that ensure regret O( x log T) in any interval of length x. In this paper we show a randomized algorithm that in an amortized sense gets a regret of O( x) for any interval when the sequence is partitioned into inter-vals arbitrarily. We empirically estimated the constant in the O() for T upto 2000 and found it to be small – around 2.1. We also experimentally evaluate the efficacy of this algorithm in predicting high frequency stock data. 1
Modifying the catalytic properties of hydrotreating NiMo–S phases by changing the electrodonor capacity of the support (2021)

The hydrogenation activity and physico-chemical characterization of a series of NiMo catalyst supported on materials with different acid-base properties (Al2O3, layered double hydroxides-derived MgAl oxides and MgO) have been investigated. The results show a clear correlation between the electrodonor capacity of the support, the negative charge density of the supported NiMo oxides and the intrinsic hydrogenation rate of the sulfided phase. Spectroscopic characterization ruled out any possible contribution derived from differences in the NiMoS2 stack or slab size distributions, as determined by high-resolution transmission electron microscopy. The experimental results obtained suggest the occurrence of an electron transfer phenomena from the support to the supported NiMoS2 slabs, being this effect stronger for supports with higher electrodonor capacity. This work presents a specific electronic support effect that goes beyond the classical dispersing and stabilizing role.
Obesity is associated with a more severe overactive bladder disease state that is effectively treated with once‐daily administration of trospium chloride extended release (2009)

Obesity is associated with a more severe OAB disease state. Once daily trospium chloride XR is efficacious in the obese patient with the OAB syndrome.
Speech quality assessment using EEG signals (2016)

The listener experience in modern audio communication systems acts as a key indicator for the entire system quality. Consequently, speech quality assessment attracts great interest from both industry and academia. Common methods for speech quality assessment are either subjective or based on subjective experiments and therefore limited in their ability to produce unbiased results. In this paper, we introduce a new EEG-based distortion measure (EBDM) for speech quality assessment. The EEG signals are represented by multi-channel autoregressive parameters. These parameters are then used, in coordination with Dynamic Time Warping algorithm to compare EEG responses of two signals with different speech quality. The method demonstrates promising preliminary indications for the possibility of using EEG signals as an objective basis for assessing speech quality degradation levels. We believe that further improvements will allow such EEG-based methods to be competitive with standard ITU-T recommended quality testing.
Low cost flip chip package design concepts for high density I/O (2002)

The semiconductor industry at large is migrating from wire bond packaging to flip chip packaging due to electrical performance requirements. With the removal of the highly resistive and inductive wire bonds, high-speed buses achieve well-controlled characteristic impedance for signal wave propagation and lower impedance for the power delivery network. However, a disadvantage of flip chip packaging is its lower input/output (I/O) routing density when compared to wire bond packaging. To meet the high I/O count for certain products, innovative flip chip bump patterns and creative routing options are needed. This paper will outline some innovative package design concepts on both die to package, defined as level 1 interconnect, and package to motherboard (MB), defined as level 2 interconnect, to increase the I/O signal routing density without increasing the package or MB cost.
Thermoplasmonics with Gold Nanoparticles: A New Weapon in Modern Optics and Biomedicine (2021)

Thermoplasmonics deals with the generation and manipulation of nanoscale heating associated with noble metallic nanoparticles. To this end, gold nanoparticles (AuNPs) are unique nanomaterials with the intrinsic capability to generate a nanoscale confined light‐triggered thermal effect. This phenomenon is produced under the excitation of a suitable light of a wavelength that matches the localized surface plasmonic resonance frequency of AuNPs. Liquid crystals (LCs) and hydrogels are temperature‐sensitive materials that can detect the host AuNPs and their photo‐induced temperature variations. In this perspective, new insight into thermoplasmonics, by describing a series of methodologies for monitoring, detecting, and exploiting the photothermal properties of AuNPs, is offered. From conventional infrared thermography to highly sophisticated temperature‐sensitive materials such as LCs and hydrogels, a new scenario in thermoplasmonic‐based, next generation, photonic components is presented and discussed. Moreover, a new road in thermoplasmonic‐driven biomedical applications, by describing compelling and innovative health technologies such as on‐demand drug‐release and smart face masks with smart nano‐assisted destruction of pathogens, is proposed. The latter represents a new weapon in the fight against COVID‐19.
Knockout of Txnip in the Intestinal Epithelial Cells Abrogates the High Fat Diet‐Induced Fructose Uptake in Mice (2018)

Thioredoxin interacting protein (Txnip) was initially identified as a protein that can bind to and inhibit thioredoxin, but it is now recognized to participate in nutrient sensing and carbohydrate metabolism. We recently discovered that Txnip binds to the fructose transporters, Glut 2 and Glut 5, to increase the fructose uptake by enterocytes. Additionally, we demonstrated that mice with diabetes induced by streptozotocin exhibit significantly higher fructose absorption compared to their non‐diabetic counterparts. Interestingly, this increase of fructose absorption in the diabetic state requires Txnip. In the current study, we studied the effects of a high fat diet (HFD) on fructose uptake and the involvement of Txnip in this process while the mice were still euglycemic. We hypothesized that high fat diet (HFD) feeding would increase fructose absorption by the jejunum compared to the controls on standard chow diet (RD), and this increase would be prevented in mice with deletion of Txnip in the intestinal epithelium despite being on a HFD. To test this hypothesis, 8‐week‐old male C57BL/6J wild‐type mice were kept on HFD for 16 weeks. At the end of 16 weeks, HFD‐fed mice not only developed insulin resistance as expected, but also displayed significantly higher fructose absorption (hepatic portal vein blood: p&lt;0.01 and liver: p&lt;0.05 vs regular diet mice, n=6–7 mice/group) 20 minutes after the oral gavage of [14C‐(U)]‐D‐fructose. Interestingly, gene and protein expressions of Txnip were also significantly higher in the jejunal samples from these mice, suggesting a potential role of Txnip in fructose uptake by the HFD‐fed mice. Since fructose absorption primarily occurs in the jejunum, using a cre‐lox breeding strategy, we generated a Txnip villin‐cre mice that lacks Txnip in the intestinal epithelial cells; and then subjected these mice and their cre counterparts to RD/HFD at 7–9 weeks of age. The preliminary data at 1 month post‐diet shows a downward trend of fructose absorption in both RD‐fed and HFD‐fed Txnip villin cre mice compared to cre‐controls that exhibited a physiological level of Txnip in villi. Therefore, our data indicate that HFD facilitates fructose uptake by the intestine, and targeted deletion of Txnip at the intestinal level can decrease absorption of dietary fructose. This finding suggests a molecular mechanism by which a high fat diet can promote additional hepatic lipid synthesis through increased fructose absorption. Support or Funding Information National Institute of Health (RTL R01DK107396) and Canadian Diabetes Association (PF‐3‐16‐5176‐AS to AS) This abstract is from the Experimental Biology 2018 Meeting. There is no full text article associated with this abstract published in The FASEB Journal .
Neurovascular coupling reflex - Contralateral stimulation apparatus and setup (2023)

Neurovascular coupling (NVC) in the brain is well studied and is one of the physical stimulation responses triggered by the central nervous system. NVC, or functional hyperemia, is described as the local blood flow increase due to the release of vasodilator chemicals from neuronal cells into vessels. This behavior also exists in the retinal vasculature. However, it was only measured in the ipsilateral retina. Assessing photic stimulation in the contralateral retina can shed light on retina-retina or brain-retina neural pathways. Emerging technologies provide new ways of measuring this effect with high spatial and temporal resolution. Adaptive optics has been used in astronomy with great results. Yet, implementing this technology in retinal fundus imaging was revolutionary in providing extremely high spatial resolution images. The RTX1 ™ is an adaptive optics retinal camera capable of ipsilateral light flicker to stimulate photoreceptors and document the induced response. The NVC in the ipsilateral retina has been successfully assessed using this equipment. Using the RTX1™ with an external flickering device, it is possible to explore contralateral stimulation's effects. The first preliminary tests show a full working prototype (contralateral stimulation) with successful software integration into the RTX1TM. A set of images was acquired to fully document the entire procedure and evaluate all components. Further evaluation will be necessary to optimize flicker-related parameters in the quest for the ipsilateral NV C response.
Disorders of Creatine Metabolism (2016)

Creatine is a physiological guanidino compound playing a major role in energy metabolism in muscle and implicated in neurotransmission in brain. The three disorders of creatine metabolism (AGAT and GAMT deficiencies and the X-linked creatine transporter defect) are a group of inborn errors of metabolism characterized by a depletion of creatine that could be easily diagnosed by mesasurement of guanidinoacetate and creatine in body fluid or cranial MRS spectroscopy. The main clinical features of these paediatric disorders are intellectual disability and speech delay and some adult patients have been described with severe language impairment and mental retardation. Although the X-linked creatine transporter defect is currently not treatable, the clinical symptoms of the two disorders of creatine synthesis should be improved by creatine supplementation emphasizing the importance of an early diagnostic.
Continuous time formulation, classification, and methods for power electronic systems (2003)

The general structure of continuous-time dynamic equations for switching power converters is investigated. One set of differential equations represents an invariant property of the network, while the remaining equations depend on control implementation and switch type. A classification scheme is proposed, and nonlinear methods appropriate to each class are examined.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Polarization Insensitive and Transparent Frequency Selective Surface for Dual Band GSM Shielding (2020)

This article proposes a single-layer, dual-band, optically transparent frequency-selective surface (FSS) for GSM shielding. The design evolves from a fractal cross dipole to achieve dual-band response, polarization insensitivity, and wide angle of incidence stability with a miniaturized size. A two-axis symmetric structure helps to provide a stable frequency response for incident waves with different polarization angles up to 60°. Capacitive loading further reduces the unit size and extends the maximum stable incident angle. The working mechanism of the design has been explained through an equivalent lumped element circuit model (ECM), which provides a generic approach to retune or optimize the design for another frequency band. Both the full-wave EM and circuit simulations are in good agreement. A prototype has been realized by screen printing a custom silver nanowire (Ag NW)-based transparent ink on a flexible polymer substrate. A decent reflection performance has been achieved from 0.71 to 1.25 GHz and from 1.73 to 2.16 GHz in measurements, which are consistent with the simulations. Optical measurements reveal a transparency of 81.6%. Printed FSS is completely flexible, and the performance does not deteriorate after bent or rolled up conditions. Field testing on a glass box demonstrates decent shielding from the incoming GSM signals. The highly transparent and flexible nature of the FSS structure makes it suitable for mounting on glass windows of cars or home environments for EM shielding purposes.
Review—Towards the Two-Dimensional Hexagonal Boron Nitride (2D h-BN) Electrochemical Sensing Platforms (2020)

Electrochemical sensing performance of two-dimensional hexagonal boron nitride (2D h-BN) has traditionally been suppressed by their intrinsic electrical insulation and deficient electron transportation mechanism. However, the excellent electrocatalytic activity, high specific surface area, N- and B-active edges, structural defects, adjustable band gap through interaction with other nanomaterials, and chemical functionalization, makes 2D h-BN ideal for many sensing applications. Therefore, finding a pathway to modulate the electronic properties of 2D h-BN while the intrinsic characteristics are well preserved, will evolve a new generation of highly sensitive and selective electrochemical (bio)sensors. That is why extensive research has recently focused on the challenge to functionalize 2D h-BN by controlling the surface chemical reactions with external species, particularly metal nanoparticles. This review summarizes the most recent progress in the application of 2D h-BN nanosheets in electrochemical (bio)sensing. We will explore the fabrication techniques of 2D h-BN for electrochemical applications followed by thorough discussion on their advantages, shortcomings, and promising possibilities as (bio)sensing platforms in near future.
ΜΕΤΑΓΩΓΗ ΤΟΥ ΣΗΜΑΤΟΣ ΜΕΣΩ ΟΞΕΙΔΟΑΝΑΓΩΓΙΚΩΝ ΑΝΤΙΔΡΑΣΕΩΝ (REDOX SIGNALING) (2015)

Eλeύθeρeς ρίζeς:Βιοχημeία και Παθολογική Βιοχημeία [ΠΑΝEΠΙΣΤΗΜΙΟ ΙΩΑΝΝΙΝΩΝ, ΣΧΟΛΗ EΠΙΣΤΗΜΩΝ ΥΓEΙΑΣ, ΤΜΗΜΑ ΙΑΤΡΙΚΗΣ]
Phase Transformation with Heat Treatment of Fe-Si Thermoelectric Material Powder Produced by Water Atomizing Process. (2000)

The powder which has a FeSi2 stoichiometric composition was obtained by a water-atomization. A phase change of the powder by annealing was characterized by XRD. The atomized powder has a fine microstructure composed with (α-Fe2Si5+ε-FeSi) phases. The phase of the atomized powder changed to β-FeSi2 phase by annealing in the temperature range from 870K to 1000K for the short time. The change to β-FeSi2 phase can be realized by only heating without holding at temperatures above 1000K. It means that the atomizing process has the same effect on shortening the annealing time to obtain β-FeSi2 phase as a mechanical alloying process. It would be expected that the thermoelectric compact with β-FeSi2 phase could be obtained by only sintering the atomized powder at a temperature lower than peritectoid point.
Portability of the fragmented l1-norm transform for massively parallel processing (2019)

White light interferometry is a major optical non-contact and therefore nondestructive testing method for nanostructures and surface reconstruction. By the reason of scanning, the data throughput is high and the resulting data stack can exceed gigabytes of raw data. Effective data compression was realized in an FPGA early in the signaling cascade. On the one hand this can significantly boost the achievable data throughput from the sensor, on the other hand the compression results in fragmented raw data with non-equidistant sampling steps and is therefore incompatible with FFT based reconstruction algorithms. In order to face this issue the fragmented l1- norm transform (flot) was developed. The flot reconstruction algorithm is a symbiosis of the l1-norm known from compressive sensing and additionally the wavelet-transform. In contrast to the traditional wavelet-transform the flot algorithm has no dependence on FFT and can quickly handle non-equidistant sampled data. Raw data is heavily independent between pixels in white light interferometry by design. Therefore, implementing the re- construction algorithm on massively parallel hardware is promising. In the last decade this usually meant data processing on GPUs. Nowadays alternatives in the form of affordable CPU clusters or easy to program FPGAs gain importance. OpenCL is a framework to accelerate highly parallel problems on all of the three platforms. In this paper the implementation of the flot algorithm in OpenCL will be explained, compared by speed and power consumption and categorized for suitable use-cases.
Supplemental Figure 9 from The Genomic Landscape of Intrinsic and Acquired Resistance to Cyclin-Dependent Kinase 4/6 Inhibitors in Patients with Hormone Receptor–Positive Metastatic Breast Cancer (2023)

&lt;p&gt;Figure S9&lt;/p&gt;
Mice expressing A53T / A30P mutant alpha-synuclein in dopamine neurons do not display behavioral deficits (2023)

ABSTRACT Alpha-synuclein has been implicated in neurodegenerative diseases such as Parkinson’s disease and Dementia with Lewy bodies, with A53T and A30P mutations shown to be disease-causing. It has been reported that transgenic mice with tyrosine hydroxylase promotor-driven expression of A53T / A30P mutant alpha-synuclein in dopamine neurons provide a useful preclinical model of these conditions by virtue of developing dopaminergic neuronal cell death and related behavioral deficits. Here, we report a lack of replication of this finding. Despite detecting robust overexpression of A53T / A30P mutant alpha-synuclein in dopamine neurons, we observed neither cell death or related behavioral deficits in these mice. Our results demonstrate that preclinical models of synucleinopathy need careful validation in the field.
Ultra-miniature computational sensors and imagers: Incorporating algorithms to yield final digital images (Conference Presentation) (2018)

Computational imaging relies on the joint design of optics and digital processing for producing the final digital image our output. Because the intermediate optical image need preserve the relevant visual information yet not necessarily "look good," a wider range of optical designs can be employed, including designs that eschew traditional optical elements such as lenses and curved mirrors. There are three primary approaches to such lensless imaging, based on 1) diffraction by special optical gratings, 2) in-line digital holography and computational phase recovery, and 3) compressive sensing using sets of pseudo-random masks. Each technique has relative strengths and weaknesses in computational burden, image accuracy, and are appropriate for different target applications.