gebhart/patrepeval huggingface dataset:
BI batch manager (2008)

Modern enterprise data warehouses have complex workloads that are notoriously difficult to manage. An important problem in workload management is to run these complex workloads 'optimally'. Traditionally this problem has been studied in the OLTP (Online Transaction Processing) context where MPL (Multi Programming Level) is used as a knob to achieve optimality. However, MPL is a tricky knob in a BI (Business Intelligence) scenario, since a low MPL can easily result in underload and a high MPL can easily result in overload and 'thrashing'.In this work we present BI Batch Manager, a workload management system to run batches of queries 'optimally' on an Enterprise Data Warehouse (EDW). It is comprised of three components: an admission control component, a scheduler and an execution control component. In order to automatically avoid underload and overload, we introduce a novel execution control mechanism, PGM (Priority Gradient Multiprogramming). In PGM, a priority gradient is created for the workload, with each query running at a distinctly different priority level. We demonstrate that this stabilizes the execution of a workload across a wide operating range. We use memory as the controlling factor for our admission control policy -- admitting batches of queries such that their memory requirement equals the available memory on the system. Our scheduling policy of largest memory query as the highest priority query further stabilizes the execution.We validate our BI Batch Manager using varying workloads on a commercial, enterprise class DBMS. We show that it effectively avoids underload and overload (thrashing) and can automatically run BI workloads with 'optimal' performance.
A Substrate-Agnostic, Submicrometer PSAS-to-PSAS Self-Alignment Technology for Heterogeneous Integration (2021)

This article presents a novel substrate-agnostic self-alignment technology with submicrometer alignment accuracy targeted for heterogeneous integrated systems. This self-alignment technology, referred to as PSAS-to-PSAS self-alignment, incorporates positive self-alignment structures (PSAS) or reflowed patterned photoresist structures that couple with other PSAS to achieve submicrometer alignment accuracy without the need for an advanced placement tool. The PSAS-to-PSAS self-alignment technology is non-substrate invasive and hence does not consume any substrate real estate. These PSAS structures can also be fabricated atop any material substrate; hence, this technology is suitable for heterogeneous integrated systems where a variety of different material substrates may be incorporated. This article discusses this PSAS-to-PSAS self-alignment technology and it provides a design analysis relating the inter-substrate gap between aligning substrates and the dimensions of the PSAS structures. The fabrication of the PSAS on two separate substrates is then performed, followed by a manual assembly process to couple the PSAS on one substrate to the PSAS on the other aligning substrate. Vernier scales are incorporated on these substrates to measure the misalignment between said substrates; submicrometer alignment is recorded. As these structures may also enable a non-permanent system configuration, alignment repeatability measurements were also performed.
Powertrain Analysis and Computational Environment (PACE) for Multi-Physics Simulations Using High Performance Computing (2016)

<div class="section abstract"><div class="htmlview paragraph">The Powertrain Analysis and Computational Environment (PACE) is a forward-looking powertrain simulation tool that is ready for a High-Performance Computing (HPC) environment. The code, written in C++, is one actor in a comprehensive ground vehicle co-simulation architecture being developed by the CREATE-GV program. PACE provides an advanced behavioral modeling capability for the powertrain subsystem of a conventional or hybrid-electric vehicle that exploits the idea of reusable vehicle modeling that underpins the Autonomie modeling environment developed by the Argonne National Laboratory. PACE permits the user to define a powertrain in Autonomie, which requires a single desktop license for MATLAB/Simulink, and port it to a cluster computer where PACE runs with an open-source BSD-3 license so that it can be distributed to as many nodes as needed. Due to its origins in Autonomie, PACE benefits from the reputation of Autonomie as a validated powertrain modeling tool capable of simulating the advanced hardware and control features of modern vehicle powertrains. But PACE brings a completely new capability to ground vehicle concept evaluation and design because it permits unrestricted operation within a high-performance cluster computing environment. The software architecture of PACE and its modular development methodology will be described in the paper, along with the unique workflow that begins with powertrain definition in Autonomie and ends as a federate in the multi-physics ground-vehicle co-simulation running on a Linux operating system on a cluster computer. An example of the extensive verification testing of PACE is presented.</div></div>
Automatic grasp planning: an operation space approach (1986)

During grasping motions, frictional forces and geometric constraint can combine to eliminate uncertainty in the location of the object. This paper incorporates the mechanics of friction and constraint in automatic planning of grasping motions. Our approach to automatic planning is centered on the use of operation space, which can be constructed for any parameterized class of operations. This approach was applied by Brost [1986] to plan planar parallel-jaw grasping motions. We extend Brost’s work to include the finite dimensions of the fingers and the finite lengths of the motions. We explore the conditions for a successful grasp, and derive constraints in the operation space. An operation satisfying all of the constraints should produce the required result.
Nano-Li4Ti5O12/Carbon Composites for Hybrid Electrochemical Ultracapacitors (2008)

Abstract not Available.
Electrophoretic detection and separation of mutant DNA using replaceable polymer matrices (2023)

The disclosure relates to a method for resolving double-stranded DNA species differing by at least one base pair. Each of the species is characterized by an iso-melting domain with a unique melting temperature contiguous with a melting domain of higher thermal stability.
Arylethynyl receptors for neutral molecules and anions: emerging applications in cellular imaging (2010)

This critical review will focus on the application of shape-persistent receptors for anions that derive their rigidity and optoelectronic properties from the inclusion of arylethynyl linkages. It will highlight a few of the design strategies involved in engineering selective and sensitive fluorescent probes and how arylacetylenes can offer a design pathway to some of the more desirable properties of a selective sensor. Additionally, knowledge gained in the study of these receptors in organic media often leads to improved receptor design and the production of chromogenic and fluorogenic probes capable of detecting specific substrates among the multitude of ions present in biological systems. In this ocean of potential targets exists a large number of geometrically distinct anions, which present their own problems to the design of receptors with complementary binding for each preferred coordination geometry. Our interest in targeting charged substrates, specifically how previous work on receptors for cations or neutral guests can be adapted to anions, will be addressed. Additionally, we will focus on the design and development of supramolecular arylethynyl systems, their shape-persistence and fluorogenic or chromogenic optoelectronic responses to complexation. We will also examine briefly how the "chemistry in the cuvet" translates into biological media (125 references).
Optimal and general out-of-order sliding-window aggregation (2019)

Sliding-window aggregation derives a user-defined summary of the most-recent portion of a data stream. For in-order streams, each window change can be handled in O (1) time even when the aggregation operator is not invertible. But streaming data often arrive inherently out-of-order, e.g., due to clock drifts and communication delays. For such streams, prior work resorted to latency-prone buffering or spent O (log n ) time for every window change, where n is the instantaneous window size. This paper presents FiBA, a novel real-time sliding window aggregation algorithm that optimally handles streams of varying degrees of out-of-orderness. FiBA is as general as the state-of-the-art and supports variable-sized windows. An insert or evict takes amortized O (log d ) time, where d is the distance of the change to the window's boundary. This means O (1) time for in-order arrivals and nearly O (1) time for slightly out-of-order arrivals, tending to O (log n ) time for the most severely out-of-order arrivals. We also prove a matching lower bound, showing optimality. At its heart, the algorithm combines and extends finger searching, lazy rebalancing, and position-aware partial aggregates. Further, FiBA can answer range queries that aggregate subwindows for window sharing. Finally, our experiments show that FiBA performs well in practice and conforms to the theoretical findings, with significantly higher throughput than O (log n ) algorithms.
Time-reversal techniques in ultrasound-assisted convection-enhanced drug delivery to the brain: Technology development and in vivo evaluation. (2010)

We describe a drug delivery method that combines time-reversal acoustics (TRA) with convection-enhanced delivery (CED) to improve the delivery of therapeutics to the interstitium of the brain. The ultrasound-assisted CED approach (UCED) circumvents the blood-brain barrier by infusing compounds through a cannula that is inserted into the brain while simultaneously delivering ultrasound to improve the penetration of pharmaceuticals. CED without ultrasound-assistance has been used to treat a variety of neural disorders, including glioblastoma multiforme, a malignancy that presents a very poor prognosis for patients. The mixed clinical success of CED suggests that the technique needs to be improved. We describe a novel TRA system that is used to infuse fluids into the brain parenchyma while simultaneously exposing the tissue to safe levels of 1-MHz, low-intensity, ultrasound energy. The system includes a com-bined infusion needle-hydrophone, a 10-channel ultralow-output impedance amplifier, a broad-band ultrasound resonator, and MATLAB®-based, TRA control and user-interface. TRA allows easy coupling of ultrasound therapy through the skull without complex phase-correction and array design. The smart targeting UCED system has been tested in vivo and results show that it provides 1-mm spatial resolution for UCED and improves tracer distribution in the brain six to eight times over CED alone.
Dynamic survivable resource pooling in mobile ad-hoc networks (2004)

The existing naming schemes for pooling resources are suitable only for static networks. We propose dynamic survivable resource pooling (DSRP) that provides a survivable naming scheme to the pool users in mobile ad-hoc networks. DSRP dynamically places the name servers (NSs) on a virtual backbone (VB): a highly distributed, scalable, and survivable mesh network formed and maintained through one-hop beacons. In this paper, DSRP focuses on pooling resources such as servers and services that are common in robotics and battlefield applications. It provides an abstraction of all the functionally equivalent servers, whereby the client can access these servers as a single entity, termed server pool. A distributed backbone mesh of NSs is used to propagate service registrations, requests, and replies.
Enabling Smart Grid with ETSI M2M standards (2012)

There are global initiatives underway to establish a communications framework for Smart Grid systems. These efforts are led by governments, standardization bodies, and industry consortiums. This paper analyzes several challenges that are associated with communicating in Smart Grid systems and assesses the suitability of using the European Telecommunications Standards Institute's machine to machine architectures and protocols (ETSI M2M) to communicate in Smart Grid systems. The paper concludes with a presentation of an ETSI M2M compliant prototyping system that demonstrates solutions to some of the communications challenges that are found in Smart Grid systems.
An Introduction For Users (1986)

Pan is a prototype and testbed for language-based editors and viewers. Its design addresses the needs of experienced users who manage complex objects such as large software systems. All of Pan''s components are multilingual, incremental, description-driven, customizable, and extensible. Viewing is facilitated by semantics-based browsing and an object model which integrates text and structure. Pan is intended to share information with other tools, allowing integration into a larger language, program, and document development environment.
Ability of tetraploid rat blastocysts to support fetal development after complementation with embryonic stem cells (2012)

This study was undertaken to generate rat offspring via tetraploid blastocyst complementation with embryonic stem (ES) cells. Tetraploid blastocysts were prepared by electrofusion of blastomeres from two-cell stage embryos, and subsequent in vivo culture for 4 days. Microinjection into the tetraploid blastocoel of an inner cell mass isolated by immunosurgery resulted in the generation of rat offspring, suggesting the successful contribution of tetraploid blastocysts to their placenta. Tetraploid blastocyst complementation was attempted with a total of 4 ES cell lines (2 lines of female karyotype and 2 lines of male karyotype). In the rESWIv-3i-5 (XX) cell line, normal-sized fetuses with heartbeats were harvested on E11.5 (12.1%), E12.5 (9.5%), and E13.5 (9.1%), but no viable fetuses were detected on E14.5. Similarly, use of the rESWIv-3i-1 (XX) cell line resulted in no viable fetus production on E14.5. Using the rESBLK2i-1 (XY) cell line, viable fetuses were harvested not only on E11.5-E13.5 (2.6-5.5%), but also on E14.5 (3.0%). The transfer of a total of 487 tetraploid blastocysts complemented with rESBLK2i-1 cells resulted in 256 implantation sites (52.6%) on E21.5, but no viable offspring was detected. Use of the rESBLK2i-1/huKO (XY) cell line also resulted in no viable offspring production on E21.5. Analyses of the methylation pattern in differentially methylated regions and transcript level of genes that are imprinted in mice (H19, Meg3, Igf2r, Peg5, and Peg10) in the E14.5 conceptuses indicated a marked difference between the ES cell-derived and control normal fetuses, but not between the tetraploid and control diploid placenta.
Total Synthesis of Five Thapsigargins: Guaianolide Natural Products Exhibiting Sub‐Nanomolar SERCA Inhibition (2007)

Herein we describe the total synthesis of five guaianolide natural products: thapsigargin, thapsivillosin C, thapsivillosin F, trilobolide and nortrilobolide. Prodrug derivatives of thapsigargin have shown selective in vivo cytotoxicity against prostate tumours and the need for further investigation of this phenomenon highlights the importance of these total syntheses. The first absolute stereochemical assignment of thapsivillosin C is also delineated.
Phase Behavior of Petroleum Reservoir Fluids (2014)

Developed in conjunction with several oil companies using experimental data for real reservoir fluids, Phase Behavior of Petroleum Reservoir Fluids introduces industry standard methods for modeling the phase behavior of petroleum reservoir fluids at different stages in the process. Keeping mathematics to a minimum, this book discusses sampling, cha
Analysis, Design, and Prototyping of Temperature Resilient Clock Distribution Networks for 3-D ICs (2015)

The 3-D integrated circuits (3-D ICs) overcome the bottlenecks in system performance and circuit density. However, their increased power and thermal density cause temperature gradients in the chip that significantly affect signal and power integrity. Temperature gradients significantly degrade the clock signal, a key signal in digital systems, which in turn degrades system performance. In this paper, we investigate the effect of thermal gradients on the clock distribution network in the 3-D ICs along with the power distribution network. We also present power-efficient compensation methods for minimizing temperature-induced skew using the thermoelectrical analysis and use them to design a custom IC in which we compare the skew, the power, and the area. Finally, using measurements, we validate the design with a field-programmable gate array-based test vehicle.
Supplementary Figure 12 from Feasibility and Safety of Personalized, Multi-Target, Adoptive Cell Therapy (IMA101): First-in-Human Clinical Trial in Patients with Advanced Metastatic Cancer (2023)

&lt;p&gt;Supplementary Figure 12&lt;/p&gt;
<title>Scheme for sensory data integration</title> (1991)

In this paper we propose a scheme for integrating data in a multi sensor system. The different sensors of the system are treated as a decision making team that cooperates and coordinates the actions and positions of the members so as to achieve a common goal. We adopt a hierarchical data-integration approach that is capable of combining the different information levels provided by the different sensors of the system.
Reduced Oral Wound Healing in the NOD Mouse Model for Type 1 Autoimmune Diabetes and Its Reversal by Epidermal Growth Factor Supplementation (2001)

Using the NOD mouse, a model for type 1 diabetes, we examined how reduced concentrations of epidermal growth factor (EGF) in the saliva, after onset of type 1 diabetes, affect oral wound healing. Diabetic NOD/LtJ mice on insulin therapy, prediabetic NOD/LtJ, and age- and sex-matched BALB/cJ mice were given a cutaneous tongue punch and allowed to undergo normal healing. With diabetes onset and a reduction in saliva-derived growth factor levels, the rate of tongue wound healing was reduced compared with nondiabetic NOD/LtJ and healthy BALB/cJ mice. Addition of exogenous EGF to the drinking water did not accelerate the rate of healing in BALB/cJ or prediabetic NOD/LtJ; however, diabetic NOD/LtJ mice exhibited accelerated wound healing similar to healthy mice. These results demonstrate that loss of growth factors from saliva is associated with profoundly reduced oral wound healing, suggesting that therapeutic treatment with topical delivery may be beneficial to patients with type 1 diabetes and oral wound complications.
Hemagglutinin-specific enzyme-linked immunosorbent assay for antibodies to influenza A and B viruses (1981)

An enzyme-linked immunosorbent assay (ELISA) was developed to detect antibodies present in human serum or nasal washes directed against influenza A or B hemagglutinin glycoproteins. The assay was modified to measure the immunoglobulin isotype specificity of the anti-hemagglutinin response in serum and nasal secretions. In the postinfection sera anti-hemagglutinin of the immunoglobulin G isotype was predominant, whereas in nasal secretions the antibody was predominantly immunoglobulin A. The antibody response detected by the ELISA manifested hemagglutinin subgroup specificity. In addition, there was a good correlation between the ELISA antibody titer and the hemagglutination-inhibition or neutralizing antibody titer. The ELISA was more sensitive than the hemagglutination-inhibition assay, and the range of antibody titers measurable by ELISA in human serum was from less than 1:20 for children who had never experienced influenza infection to 1:400,000 for adults convalescing from a secondary infection. With more sensitive tests to detect antibody to the influenza hemagglutinin it should be possible to determine the relative contribution of local and systemic immunity to resistance to influenza virus infection.
ChemInform Abstract: The Evolution of Pd0/PdII‐Catalyzed Aromatic Fluorination (2016)

Abstract Review: 39 refs.
Using sinusoidal stimuli and Fourier analyses for memory IC testing (2002)

This paper explores the utilization of sinusoidal stimuli and Fourier analyses to test static RAM integrated circuits. Two different tests are investigated, a writing test with a sinusoidal stimulus on the DATA line and a reading test with a sinusoidal stimulus on an address line. Up to now, results show that numerous types of faults and defects can be detected and even identified. Sensitivity of the method with respect to parameter variations is also investigated.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Towards spatially varying gloss reproduction for 3D printing (2020)

3D printing technology is a powerful tool for manufacturing complex shapes with high-quality textures. Gloss, next to color and shape, is one of the most salient visual aspects of an object. Unfortunately, printing a wide range of spatially-varying gloss properties using state-of-the-art 3D printers is challenging as it relies on geometrical modifications to achieve the desired appearance. A common post-processing step is to apply off-the-shelf varnishes that modify the final gloss. The main difficulty in automating this process lies in the physical properties of the varnishes which owe their appearance to a high concentration of large particles and as such, they cannot be easily deposited with current 3D color printers. As a result, fine-grained control of gloss properties using today's 3D printing technologies is limited in terms of both spatial resolution and the range of achievable gloss. We address the above limitations and propose new printing hardware based on piezo-actuated needle valves capable of jetting highly viscous varnishes. Based on the new hardware setup, we present the complete pipeline for controlling the gloss of a given 2.5 D object, from printer calibration, through material selection, to the manufacturing of models with spatially-varying reflectance. Furthermore, we discuss the potential integration with current 3D printing technology. Apart from being a viable solution for 3D printing, our method offers an additional and essential benefit of separating color and gloss fabrication which makes the process more flexible and enables high-quality color and gloss reproduction.
Final report of the SIM.QM-S7 supplementary comparison, trace metals in drinking water (2017)

SIM.QM-S7 was performed to assess the analytical capabilities of National Metrology Institutes (NMIs) and Designated Institutes (DIs) of SIM members (or other regions) for the accurate determination of trace metals in drinking water. The study was proposed by the coordinating laboratories National Research Council Canada (NRC) and Centro Nacional de Metrologia (CENAM) as an activity of Inorganic Analysis Working Group (IAWG) of Consultative Committee for Amount of Substance - Metrology in Chemistry and Biology (CCQM). Participants included 16 NMIs/DIs from 15 countries. No measurement method was prescribed by the coordinating laboratories. Therefore, NMIs used measurement methods of their choice. However, the majority of NMIs/DIs used ICP-MS. This SIM.QM-S7 Supplementary Comparison provides NMIs/DIs with the needed evidence for CMC claims for trace elements in fresh waters and similar matrices. Main text To reach the main text of this paper, click on Final Report . Note that this text is that which appears in Appendix B of the BIPM key comparison database kcdb.bipm.org/ . The final report has been peer-reviewed and approved for publication by the CCQM, according to the provisions of the CIPM Mutual Recognition Arrangement (CIPM MRA).