gebhart/patrepeval huggingface dataset:
ESR-und ENDOR-Untersuchungen der Autoxidationsprodukte des Adrenalons und analoger Verbindungen / ESR and ENDOR Investigations of the Autoxidation Products of Adrenalone and Related Compounds (1986)

Abstract The signs of the proton coupling constants of adrenalone semiquinone and related compounds were determined by ENDOR and TRIPLE resonance studies, thereby verifying the increment system described in our previous paper [2], Comparison of the spin-distribution of several substituted acylcatechols showed the conformational influence on the coupling constants due to mesomeric interaction of the carbonyl group with the aromatic π-system. Adrenalone and other N -monosubstituted catecholamines showed rather stable secondary radi­cals after the decay of the primary semiquinone radical. They were identified as substituted dihydropyrazinium cation radicals after selective deuteration and comparison of their ESR-, ENDOR- and TRIPLE-resonance spectra with those of the non-deuterated species. They are formed by cyclic condensation of two molecules with subsequent oxidation.
PROTON CONDUCTION IN ANTIMONIC ACID AT MEDIUM TEMPERATURES IN THE PRESENCE OF WATER VAPOR (1983)

Abstract Antimonic acid was found to exhibit a relatively high proton conductivity at medium temperatures of 100–300 °C in the presence of water vapor. For example, the conductivity as high as 1×10−4 S·cm−1 could be maintained for 8 h at 200 °C under the water vapor pressure of 13 kPa. This stable conductivity at medium temperature was found to be attributable to the thermal stability of the water of constitution of Sb2O5·2H2O.
Why Delay? Early Enteral Nutrition in Pediatric Burn Patients Improves Outcomes (2020)

Children who sustain moderate to large surface area burns present in a hypermetabolic state with increased caloric and protein requirements. A policy was implemented at our institution in 2017 to initiate enteral nutrition (EN) in pediatric burn patients within 4 hours of admission. The authors hypothesize that early EN (initiated within 4 hours of admission) is more beneficial than late EN (initiated ≥ 4 hours from admission) for pediatric burn patients and is associated with decreased rates of pneumonia, increased calorie and protein intake, fewer feeding complications, a shorter Intensive Care Unit (ICU) length of stay (LOS), and a reduced hospital LOS. Children who sustained a total body surface area (TBSA) burn injury ≥ 10% between 2011 and 2018 were identified in a prospectively maintained burn registry at Children's Hospital Colorado. Patients were stratified into two groups for comparison: early EN and late EN. The authors identified 132 pediatric burn patients who met inclusion criteria, and most (60%) were male. Approximately half (48%) of the study patients were in the early EN group. The early EN group had lower rates of underfeeding during the first week (P = .014) and shorter ICU LOS (P = .025). Achieving and sustaining adequate nutrition in pediatric burn patients with moderate to large surface area burn injuries are critical to recovery. Early EN in pediatric burn patients is associated with decreased underfeeding and reduced ICU LOS. The authors recommend protocols to institute feeding for patients with burns ≥ 10% TBSA within 4 hours of admission at all pediatric burn centers.
Optical properties of Si-doped GaN (1997)

The optical properties of n-type GaN are investigated for Si doping concentrations ranging from 5×1016 to 7×1018 cm−3. The photoluminescence linewidth of the near-band gap optical transition increases from 47 to 78 meV as the doping concentration is increased. The broadening is modeled in terms of potential fluctuations caused by the random distribution of donor impurities. Good agreement is found between experimental and theoretical results. The intensity of the near-band-gap transition increases monotonically as the doping concentration is increased indicating that nonradiative transitions dominate at a low doping density. The comparison of absorption, luminescence, reflectance, and photoreflectance measurements reveals the absence of a Stokes shift at room temperature demonstrating the intrinsic nature of the near-band edge transition.
Cellulose Nanocrystals (CNCs) Induced Crystallization of Polyvinyl Alcohol (PVA) Super Performing Nanocomposite Films (2019)

This study is aimed to explore the properties of cellulose nanocrystals (CNC)/polyvinyl alcohol (PVA) composite films with and without 1,2,3,4-butane tetracarboxylic acid (BTCA), a nontoxic crosslinker. CNC and CNC-PVA nanocomposite films are prepared using solution-casting technique. Differential scanning calorimetry (DSC) analyses show that crosslinking increased the glass transition temperature but reduced the melting temperature and crystallinity. Furthermore, high CNC concentrations in the PVA matrix interfere with PVA crystallinity, whereas in specific ratio between CNC and PVA, two different crystalline structures are observed within the PVA matrix. Film surfaces and fracture topographies characterized using scanning electron microscope indicate that at certain CNC-PVA ratios, micron-sized needle-like crystals have formed. These crystalline structures correlate with the remarkable improvement in mechanical properties of the CNC-PVA nanocomposite films, that is, enhanced tensile strain and toughness to 570% and 202 MJ m<sup>-3</sup> , respectively, as compared to pristine PVA. BTCA enhances the tensile strain, ultimate tensile stress, toughness, and modulus of CNC films compared to pristine CNC films. Water absorption of crosslinked CNC and CNC-PVA nanocomposite films is significantly reduced, while film transparency is significantly improved as a function of PVA and crosslinker content. The presented results indicate that CNC-PVA nanocomposite films may find applications in packaging, and though materials applications.
Detection of 3D objects in cluttered scenes using hierarchical eigenspace (1997)

This paper proposes a novel method to detect three-dimensional objects in arbitrary poses and sizes from a complex image and to simultaneously measure their poses and sizes using appearance matching. In the learning stage, for a sample object to be learned, a set of images is obtained by varying pose and size. This large image set is compactly represented by a manifold in compressed subspace spanned by eigenvectors of the image set. This representation is called the parametric eigenspace representation. In the object detection stage, a partial region in an input image is projected to the eigenspace, and the location of the projection relative to the manifold determines whether this region belongs to the object, and what its pose is in the scene. This process is sequentially applied to the entire image at different resolutions. Experimental results show that this method accurately detects the target objects.
Crucial Role of FcγRIIa (CD32) in Assessment of Functional Anti–Streptococcus pneumoniaeAntibody Activity in Human Sera (1999)

Immunoglobulin G (IgG)-mediated phagocytosis by polymorphonuclear leukocytes (PMNL) constitutes the main defense against Streptococcus pneumoniae. Two leukocyte IgG receptors, FcgammaRIIa and FcgammaRIIIb, are constitutively expressed on PMNL. Blocking experiments showed FcgammaRIIa is crucial for opsonophagocytosis of serum-opsonized S. pneumoniae. The biallelic, genetically determined FcgammaRIIa polymorphism (FcgammaRIIa-R131 vs. IIa-H131) determines the capacity of IgG2-mediated phagocytosis via this receptor. Comparative studies with PMNL from donors either homozygous for FcgammaRIIa-R131 or IIa-H131 showed the latter had higher phagocytic capacity. These results were confirmed in FcgammaRIIa-R131- and FcgammaRIIa-H131-transfected IIA1.6 cells. The performance of FcgammaRIIa-transfected cells in S. pneumoniae phagocytosis was validated using sera from adults and children. Serum-induced phagocytic activity depended mainly on anti-pneumococcal IgG2 antibodies. Results obtained with PMNL and IIA1.6 cells showed high correlation (r=0.94; P<.001), and support that FcgammaRIIa transfectants are a good alternative to PMNL as effector cells in opsonophagocytosis assays.
Low melting Li/K/Cs acetate salt mixtures as new ionic media for catalytic applications – first physico-chemical characterization (2012)

In order to expand the temperature limits of Supported Ionic Liquid Phase (SILP) or Solid Catalyst with Ionic Liquid Layer (SCILL) systems to higher operation temperatures, the mixture of lithium acetate, potassium acetate, and caesium acetate (molar ratio of 0.2/0.275/0.525) has been studied in detail. Physico-chemical properties of the bulk melt are reported together with stability data of the modern salt on various solid support materials showing attractive properties for many potential high temperature applications.
Photophysics of Main-Chain Polychromophores Prepared by Acyclic Diene Metathesis Polymerization (1997)

A series of bis(vinylthienyl)silane monomers were prepared by reaction of 2 equiv of (vinylthienyl)lithium or (vinylthienyl)magnesium bromide with different dichlorosilicon dialkyls. The monomers react with the Schrock initiator Mo(NAr)(CHCMe2Ph)(OCMe(CF3)2)2 (Ar = 2,6-diisopropylphenyl), via the acyclic diene metathesis polymerization (ADMET) mechanism, to give poly(silanyl−dithienylethene) derivatives in excellent yield. GPC data suggest that the resulting polymers have short repeat sequences. Interchromophore cooperativity is evident, as a low energy emission, for polymer structures that have smaller side groups. This phenomenon is similar to the chromophore cooperativity observed in polymers containing stilbene fragments along the backbone.
South Korea's Land Reform and Democracy (2013)

This article aims to examine what sort of impact the South Korean land reform in 1950 had on democracy. I will mainly analyze (1) the international background, (2) legislation and execution, and (3) the change in relation between farmers and the state. In the context of the Cold War, this reform aimed to prevent socialist revolution by accommodating the demands of peasant revolution from the top. The land reform's social democratic character was minimized in its legislative process. The reform played a critical role in establishing the socioeconomic base for the liberal democratic and capitalist system. The National Assembly's management of the legislative process also provided a valuable experience for a procedural democracy. And as a result of the reform, the rural communities became more equal. The fact that farmers were liberated from the landlord system was also important in creating a pillar for rural democratization in the long run. Despite these positive points, the South Korean land reform also had its shortcomings and displayed democratic limitations. With the path to the development of farmers' autonomous organizations blocked, the real power in the rural communities at the myeon-level rested with the local administrators and elders. The South Korean land reform limited South Korean democracy to the framework of anticommunism and liberal democracy in the context of a global Cold War, while providing an experience in procedural democracy and the structural conditions for rural democratization.
Evidence for Linkage Disequilibrium Between Fc gamma RIIIa-V158F and Fc gamma RIIa-H131R Polymorphisms in White Patients, and for an Fc gamma RIIIa-Restricted Influence on the Response to Therapeutic Antibodies (2008)

International audience
GreenABR (2022)

Adaptive bitrate (ABR) algorithms aim to make optimal bitrate decisions in dynamically changing network conditions to ensure a high quality of experience (QoE) for the users during video streaming. However, most of the existing ABRs share the limitations of predefined rules and incorrect assumptions about streaming parameters. They also come short to consider the perceived quality in their QoE model, target higher bitrates regardless, and ignore the corresponding energy consumption. This joint approach results in additional energy consumption and becomes a burden, especially for mobile device users. This paper proposes GreenABR, a new deep reinforcement learning-based ABR scheme that optimizes the energy consumption during video streaming without sacrificing the user QoE. GreenABR employs a standard perceived quality metric, VMAF, and real power measurements collected through a streaming application. GreenABR's deep reinforcement learning model makes no assumptions about the streaming environment and learns how to adapt to the dynamically changing conditions in a wide range of real network scenarios. GreenABR outperforms the existing state-of-the-art ABR algorithms by saving up to 57% in streaming energy consumption and 60% in data consumption while achieving up to 22% more perceptual QoE due to up to 84% less rebuffering time and near-zero capacity violations.
Data from Phase II Clinical Trial of Amatuximab, a Chimeric Antimesothelin Antibody with Pemetrexed and Cisplatin in Advanced Unresectable Pleural Mesothelioma (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; Amatuximab is a chimeric monoclonal antibody to mesothelin, a cell surface glycoprotein highly expressed in malignant pleural mesothelioma (MPM). On the basis of its synergy with chemotherapy in preclinical studies, we evaluated the antitumor activity of amatuximab plus pemetrexed and cisplatin in patients with unresectable MPM.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; In a single-arm phase II study, amatuximab (5 mg/kg) was administered on days 1 and 8 with pemetrexed (500 mg/m&lt;sup&gt;2&lt;/sup&gt;) and cisplatin (75 mg/m&lt;sup&gt;2&lt;/sup&gt;) on day 1 of 21-day cycles for up to six cycles. Patients with response or stable disease received amatuximab maintenance until disease progression. Primary endpoint was progression-free survival (PFS) at 6 months. Secondary endpoints were overall survival (OS), response rate, and safety.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; Eighty-nine patients were enrolled at 26 centers. Median of five cycles (range, 1–6) of combination treatment was administered, and 56 (63%) patients received amatuximab maintenance. Combination therapy resulted in no overlapping toxicities. Eleven patients (12.4%) had amatuximab-related hypersensitivity reactions. Responses included partial responses in 33 (40%) and stable disease in 42 (51%). Six-month PFS rate was 51% [95% confidence interval (CI), 39.1–62.3)], median PFS was 6.1 months (95% CI, 5.8–6.4), and median OS was 14.8 months (95% CI, 12.4–18.5) with 29 patients alive at data cut-off.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; Amatuximab with pemetrexed and cisplatin was well tolerated with objective tumor response or stable disease rate of 90% by independent radiologic review. Although PFS was not significantly different from historical controls, the median OS was 14.8 months with a third of patients alive and 5 continuing to receive amatuximab at the time of analysis. &lt;i&gt;Clin Cancer Res; 20(23); 5927–36. ©2014 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
TRoVE: Transforming Road Scene Datasets into Photorealistic Virtual Environments (2022)

High-quality structured data with rich annotations are critical components in intelligent vehicle systems dealing with road scenes. However, data curation and annotation require intensive investments and yield low-diversity scenarios. The recently growing interest in synthetic data raises questions about the scope of improvement in such systems and the amount of manual work still required to produce high volumes and variations of simulated data. This work proposes a synthetic data generation pipeline that utilizes existing datasets, like nuScenes, to address the difficulties and domain-gaps present in simulated datasets. We show that using annotations and visual cues from existing datasets, we can facilitate automated multi-modal data generation, mimicking real scene properties with high-fidelity, along with mechanisms to diversify samples in a physically meaningful way. We demonstrate improvements in mIoU metrics by presenting qualitative and quantitative experiments with real and synthetic data for semantic segmentation on the Cityscapes and KITTI-STEP datasets. All relevant code and data is released on github (https://github.com/shubham1810/trove_toolkit).
Five-Year Two-Center Retrospective Comparison of Central Laboratory Glucose to GEM 4000 and ABL 800 Blood Glucose: Demonstrating the (In)adequacy of Blood Gas Glucose (2019)

The GEM ABG glucose is associated with a higher frequency of moderate to severe glucose clinical outliers, especially between 0800 and 0200, increased CL testing and higher average patient glucoses.
Enrichment of Two Isomeric Heparin Oligosaccharides Exhibiting Different Affinities toward Monocyte Chemoattractant Protein-1 (2016)

Chemokine-GAG interactions are crucial to facilitate chemokine immobilization, resulting in the formation of chemokine gradients that guide cell migration. Here we demonstrate chromatographic isolation and purification of two heparin hexasaccharide isomers that interact with the oligomeric chemokine Monocyte Chemoattractant Protein-1 (MCP-1)/CCL2 with different binding affinities. The sequences of these two hexasaccharides were deduced from unique MS/MS product ions and HPLC compositional analysis. Ion mobility mass spectrometry (IM-MS) showed that the two isolated oligosaccharides have different conformations and both displayed preferential binding for one of the two distinct conformations known for MCP-1 dimers. A significant shift in arrival time distribution of close to 70 Å<sup>2</sup> was observed, indicating a more compact protein:hexasaccharide conformation. Clear differences in the MS spectra between bound and unbound protein allowed calculation of K<sub>d</sub> values from the resulting data. The structural difference between the two hexasaccharides was defined as the differential location of a single sulfate at either C-6 of glucosamine or C-2 of uronic acid in the reducing disaccharide, resulting in a 200-fold difference in binding affinity for MCP-1. These data indicate sequence specificity for high affinity binding, supporting the view that sulfate position, and not simply the number of sulfates, is important for heparan sulfate protein binding.
Enabling hydrate-based methane storage under mild operating conditions by periodic mesoporous organosilica nanotubes (2023)

Biomethane is a renewable natural gas substitute produced from biogas. Storage of this sustainable energy vector in confined clathrate hydrates, encapsulated in the pores of a host material, is a highly promising avenue to improve storage capacity and energy efficiency. Herein, a new type of periodic mesoporous organosilica (PMO) nanotubes, referred to as hollow ring PMO (HR-PMO), capable of promoting methane clathrate hydrate formation under mild working conditions (273 K, 3.5 MPa) and at high water loading (5.1 g water/g HR-PMO) is reported. Gravimetric uptake measurements reveal a steep single-stepped isotherm and a noticeably high methane storage capacity (0.55 g methane/g HR-PMO; 0.11 g methane/g water at 3.5 MPa). The large working capacity throughout consecutive pressure-induced clathrate hydrate formation-dissociation cycles demonstrates the material's excellent recyclability (97% preservation of capacity). Supported by ex situ cryo-electron tomography and x-ray diffraction, HR-PMO nanotubes are hypothesized to promote clathrate hydrate nucleation and growth by distribution and confinement of water in the mesopores of their outer wall, along the central channels of the nanotubes and on the external nanotube surface. These findings showcase the potential for application of organosilica materials with hierarchical and interconnected pore systems for pressure-based storage of biomethane in confined clathrate hydrates.
Exploring a Multidimensional Representation of Documents and Queries (extended version) (2010)

In Information Retrieval (IR), whether implicitly or explicitly, queries and documents are often represented as vectors. However, it may be more beneficial to consider documents and/or queries as multidimensional objects. Our belief is this would allow building "truly" interactive IR systems, i.e., where interaction is fully incorporated in the IR framework. The probabilistic formalism of quantum physics represents events and densities as multidimensional objects. This paper presents our first step towards building an interactive IR framework upon this formalism, by stating how the first interaction of the retrieval process, when the user types a query, can be formalised. Our framework depends on a number of parameters affecting the final document ranking. In this paper we experimentally investigate the effect of these parameters, showing that the proposed representation of documents and queries as multidimensional objects can compete with standard approaches, with the additional prospect to be applied to interactive retrieval.
Abstract 199: Increased killing potential of ex vivo differentiated human natural killer cells in the presence of HOXB4 (2014)

Abstract We have previously shown that human umbilical cord blood CD34+ progenitor cells undergo in vitro differentiation into functional NK cells and that their co-culture in the presence of HOXB4 transduced stromal MS5 cells resulted in an increase in differentiated NK number. The present study was conducted to compare the stromal effect on NK lytic potential in the presence and absence of HOXB4. Our results provide evidence that HOXB4 transduced MS5 cells as compared to transduced, GFP (+) MS5 cells induced highly differentiated cytotoxic NK cells. Importantly, this difference was not due to the expression of activating NK receptors but was associated with an increased induction of granzyme B transcription and degranulation in response to stimulation with NK cell susceptible targets. DNA microarray-based global transcriptional profiling confirmed the up-regulation of Granzyme B. We provide evidence that HOXB4 is a crucial regulator of NK lytic function and that its use in generating functional NK cells with increased lytic potential may be significant for hematologic malignancies. Our findings provide further evidence that HOXB4 is a crucial regulator of NK function and that its use in generating functional NK cells with increased lytic potential may be significant for cancer immunotherapy. Citation Format: Salem Chouaib, Arash Nanbakhsh, Cécile Pochon, Sophie Amsellem, Gianfranco Pittari, Jean-Henri Bourhis. Increased killing potential of ex vivo differentiated human natural killer cells in the presence of HOXB4. [abstract]. In: Proceedings of the 105th Annual Meeting of the American Association for Cancer Research; 2014 Apr 5-9; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2014;74(19 Suppl):Abstract nr 199. doi:10.1158/1538-7445.AM2014-199
DISSOCIATIVE CHEMISORPTION OF H2(D2) AT Fe(110) (1994)

The dissociative chemisorption of H 2 (D 2 ) at a Fe(110) surface has been studied as a function of translational energy E T , internal energy E i , incident angle θ i , and surface temperature T s . Adsorption is activated, the sticking probability increasing steadily with translational energy with no evidence of a threshold for dissociation. Within experimental error there is no isotope effect or surface temperature dependence (180 K&lt;T s &lt;400 K). Using seeded beams at constant translational energy, sticking on a clean surface is insensitive to the internal state distribution of the incident molecules, consistent with a barrier to dissociative chemisorption in the entrance channel. For translational energies below 0.2 eV sticking deviates from normal energy scaling, momentum parallel to the surface strongly inhibiting dissociative chemisorption. Dissociaton is interpreted in terms of a localised surface site for dissociative chemisorption at low energies.