gebhart/patrepeval huggingface dataset:
High resolution solid state NMR in paramagnetic metal-organic frameworks (2022)

We study the metal-organic framework (MOF) ZIF-67 with <sup>1</sup>H and <sup>13</sup>C nuclear magnetic resonance (NMR). In addition to the usual orbital chemical shifts, we observe spinning sideband manifolds in the NMR spectrum due to hyperfine interactions of the paramagnetic cobalt with <sup>1</sup>H and <sup>13</sup>C. Both orbital and paramagnetic chemical shifts are in good agreement with values calculated from first principles, allowing high-confidence assignment of the observed peaks to specific sites within the MOF. Our measured resonance shifts, line shapes, and spin lattice relaxation rates are also consistent with calculated values. We show that molecules in the pores of the MOF can exhibit high-resolution NMR spectra with fast spin lattice relaxation rates due to dipole-dipole couplings to the Co<sup>2+</sup> nodes in the ZIF-67 lattice, showcasing NMR spectroscopy as a powerful tool for identification and characterization of "guests" that may be hosted by the MOF in electrochemical and catalytic applications.
Engineering of Blood Vessels from Acellular Collagen Matrices Coated with Human Endothelial Cells (2006)

Small-caliber synthetic grafts used for coronary bypass artery grafting are compromised by thrombogenicity and accelerated intimal thickening, resulting in early graft occlusion. Herein we describe the fabrication and physical properties of small-caliber blood vessels using decellularized porcine aortic segments. These vessels were further coated with human saphenous vein endothelial cells (HSVECs) for future clinical applications. Chemical staining of decellularized vessels showed that they preserved their native matrix architecture, including several collagen layers in between internal and external elastin layers. The burst pressure for the decellularized vessels was higher than 1,000 mmHg. HSVECs, seeded on the luminal side, adhered to the matrix and formed a uniform monolayer. HSVEC-seeded vessels produced prostaglandin I2 and released vasoactive agents in response to the calcium ionophore A23187. These results show that engineered blood vessels coated with the host endothelial cells possess morphologic and functional characteristics of human small-caliber vessels. Tissue-engineered vessels may potentially be useful clinically as vascular grafts.
Positron motion in metals. II. Models for data analysis (1984)

Two aspects of the momentum distribution function for positrons interacting with phonons and electrons in metals are studied. First, a simple approximation to the theoretical expression for the momentum distribution is found. It is used to clarify the meaning of the apparent mass in a Gaussian distribution introduced in the analysis of experimental data. Secondly, numerical evaluation of the theoretical momentum spectrum of the annihilating electron–positron pairs demonstrates the inadequacies of the Gaussian approximation. This leads to a new method of analysis of experimental data using the realistic distribution. This method allows one to obtain separately the positron quasiparticle mass and the positron–phonon coupling strength.
μJ Pulses from an Integrated Ytterbium Fiber System (2011)

Energy scaling of μJ fs pulses from monolithic YDFAs is limited by pulse pedestal formation. We demonstrate a chirped-pulse fiber-amplifier that uses a newly developed dispersion compensating fiber stretcher matching the dispersion of a grating pair. OCIS codes: (060.2320) Fiber optics amplifiers and oscillators; (320.7090) Ultrafast Lasers.
Quinone Methide Alkylation of Deoxycytidine (1997)

ADVERTISEMENT RETURN TO ISSUEPREVNoteNEXTQuinone Methide Alkylation of DeoxycytidineSteven E. Rokita, Jianhong Yang, Praveen Pande, and William A. GreenbergView Author Information Department of Chemistry and Biochemistry, University of Maryland, College Park, Maryland 20742, and Department of Chemistry, State University of New York at Stony Brook, Stony Brook, New York 11794 Cite this: J. Org. Chem. 1997, 62, 9, 3010–3012Publication Date (Web):May 2, 1997Publication History Received3 January 1997Published online2 May 1997Published inissue 1 May 1997https://doi.org/10.1021/jo9700336Copyright © 1997 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views621Altmetric-Citations65LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (106 KB) Get e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Alcohols,Cytosine,Genetics,Post-translational modification,Quinones Get e-Alerts
Buttressing and fractional spreading of Tenerife, an experimental approach on the formation of rift zones (2003)

The island of Tenerife is composed of three Miocene shields, which are centered by the Cañadas volcano since the Pliocene. Tenerife sits on more than 2 km thick oceanic sediments. Quaternary volcanism of the Cañadas series and giant landslides were principally confined to triaxial rift zones. The mechanism of triaxial rifting, however, has remained unclear. Physical analog models show that these rift zones may have formed by gravity‐driven lateral escape of island segments, induced by loading of the deformable substratum. For experiments scaled to Tenerife, three adjacent sand cones were mounted onto viscous PDMS substratum. Gravitational spreading caused circumferential expansion of each cone, until a large edifice (Cañadas) was constructed in their center. The older cones now acted each as a buttress; radial fractures were overprinted by fractional spreading of the Cañadas edifice. This resulted in formation of three main extensional zones, resembling the triaxial rifting configuration of Tenerife.
MID UV Resist Materials Containing Pyridinium Ylides (1988)

Polymers containing pyridinium-ylide units were prepared as water soluble MID UV resist materials. The absorption maxima of the N-iminopyridinium ylides are centered around 320 nm. Upon exposure the ylide sensitizer bleaches cleanly and undergoes two competing reactions, leading via a singlet state to 1,2-diazepines and via a triplet state to pyridine and nitrenes. Both reactions are accompanied by a change in polarity and can be used in the application as photoresists. This pronounced polarity change renders the polymers hydrophobic and water repellant. Therefore negative images can be obtained by development with pure water. Due to a quantum yield below 0.1 the sensitivity is low, but can be enhanced by addition of sensitizers.
Complete loss of the DNAJB6 G/F domain and novel missense mutations cause distal-onset DNAJB6 myopathy (2015)

Our patients expand the phenotypic spectrum of DNAJB6-myopathy and allow tentative genotype-phenotype specifications. Combining with previous studies, the clinical severity spectrum is as follows: ΔG/F and Phe91 mutations, most severe; Phe100, Pro96, Phe89 mutations, intermediate; and Phe93, least severe. As it stands presently, proximal G/F domain mutations (Phe89, Phe91, Phe93) cause proximal limb-girdle myopathy, while distal G/F mutations (Pro96, Phe100) cause distal-onset myopathy. While all mutations affect the G/F-J interaction, each likely does so in different unknown extents or ways. One mutation, ΔG/F, causes its associated severe distal-onset myopathy phenotype in a clear way, through generation of a G/F domain-lacking DNAJB6 protein.
Network Assisted Wi-Fi Direct Based on Media Independent Services Framework for Allocating Optimized Radio Resources (2016)

Wi-Fi Direct is a promising and available technology for device-to-device (D2D) proximity communications. To improve the performances of Wi-Fi Direct communication, optimized radio resource allocations are important. This paper proposes network assisted Wi-Fi Direct (NAWD), which operates based on the media independent services framework of IEEE 802.21 standard, for optimizing radio resource allocations. The NAWD is enhanced Wi-Fi Direct with the assistance of infrastructure networks (e.g., cellular network) and allocates radio resources (e.g., frequency channels and transmit power) to reduce radio interferences among Wi-Fi Direct devices (e.g., smart phones and set-top boxes). The NAWD includes mechanisms for gathering configuration information (e.g., location information and network connection information) of Wi-Fi Direct devices and allocating optimized radio resources (e.g., frequency channels and transmit power) to reduce radio interferences among Wi-Fi Direct devices. Simulation results show that the proposed NAWD increases significantly SINR, power efficiency, and areal capacity compared to legacy Wi-Fi Direct, where areal capacity is total traffic throughput per unit area.
Pressure effects on the phase behavior of a propylene/water/surfactant mixture (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPressure effects on the phase behavior of a propylene/water/surfactant mixtureEric J. Beckman and Richard D. SmithCite this: J. Phys. Chem. 1991, 95, 8, 3253–3257Publication Date (Print):April 1, 1991Publication History Published online1 May 2002Published inissue 1 April 1991https://pubs.acs.org/doi/10.1021/j100161a053https://doi.org/10.1021/j100161a053research-articleACS PublicationsRequest reuse permissionsArticle Views101Altmetric-Citations24LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Towards 400G/1T flexible optical transport networks (2013)

In this paper, we describe the physical layer technologies, which should enable to still increase the global capacity of the currently deployed 100 Gbps WDM transmission systems, while making more flexible and more energy-efficient the optical transport networks. We address, in particular, the networks which will dynamically adapt their capacity to the service connection requirements, thanks to the appropriated allocation of spectrum resources and adaptation of modulation formats. In these flexible and energy-efficient optical transport networks, all-optical switching nodes will be able to add/drop not only the 400G/1T super-channels but also the sub-channels which constitute them, in order to lighten the load of the IP layer. Moreover, appropriated multi-layer network architectures should relax the capacity constraints weighing over the WDM transmission infrastructure.
ARES: A Reading Comprehension Ensembling Service (2020)

Anthony Ferritto, Lin Pan, Rishav Chakravarti, Salim Roukos, Radu Florian, J. William Murdock, Avi Sil. Proceedings of the 2020 Conference on Empirical Methods in Natural Language Processing: System Demonstrations. 2020.
MBX-500, a Hybrid Antibiotic with In Vitro and In Vivo Efficacy against Toxigenic Clostridium difficile (2012)

Clostridium difficile infection (CDI) causes moderate to severe disease, resulting in diarrhea and pseudomembranous colitis. CDI is difficult to treat due to production of inflammation-inducing toxins, resistance development, and high probability of recurrence. Only two antibiotics are approved for the treatment of CDI, and the pipeline for therapeutic agents contains few new drugs. MBX-500 is a hybrid antibacterial, composed of an anilinouracil DNA polymerase inhibitor linked to a fluoroquinolone DNA gyrase/topoisomerase inhibitor, with potential as a new therapeutic for CDI treatment. Since MBX-500 inhibits three bacterial targets, it has been previously shown to be minimally susceptible to resistance development. In the present study, the in vitro and in vivo efficacies of MBX-500 were explored against the Gram-positive anaerobe, C. difficile. MBX-500 displayed potency across nearly 50 isolates, including those of the fluoroquinolone-resistant, toxin-overproducing NAP1/027 ribotype, performing as well as comparator antibiotics vancomycin and metronidazole. Furthermore, MBX-500 was a narrow-spectrum agent, displaying poor activity against many other gut anaerobes. MBX-500 was active in acute and recurrent infections in a toxigenic hamster model of CDI, exhibiting full protection against acute infections and prevention of recurrence in 70% of the animals. Hamsters treated with MBX-500 displayed significantly greater weight gain than did those treated with vancomycin. Finally, MBX-500 was efficacious in a murine model of CDI, again demonstrating a fully protective effect and permitting near-normal weight gain in the treated animals. These selective anti-CDI features support the further development of MBX 500 for the treatment of CDI.
FDTD analysis of wire antenna used for process plasma (2002)

There is a strong desire to expand the area of the substrate in the semiconductor process. In order to produce and control the plasma in a large area by using radiofrequency, it is important to clarify how the electromagnetic field distribution depends on the antenna shape or the feeding method. However, the analysis of electromagnetic field in the process plasma has not been reported because the plasma medium is strongly dispersive. Moreover, the real part of the complex permittivity of the plasma could be negative in the cutoff frequency region. The FDTD method has been widely used for many problems including the plasma medium. In this paper, the FDTD analysis of wire antenna used for the plasma process is presented considering the ion sheath effect.
Full-Scale Test and Numerical Simulation of a Truck Impacting a Group of Side-by-Side Piles (2014)

This paper describes a study of the behavior of a group of piles under impact loading. Many structures such as bridge piers, offshore platforms, or berthing foundations can be subjected to the horizontal impacts from ships during their lifetime in which the system failure would have serious consequences. Guardrails for road side safety are another type of impact-resisting system that are extensively used and have a direct relation to human life and cost. Moreover groups of piles can serve as an efficient and relatively cost-effective protective structure around critical and important facilities. Prediction of the system response during the impact can lead to a more effective and economical design. There has been a very limited amount of experimental work on lateral response of group piles under impact loading in particular in the field of full-scale tests. This paper describes a full-scale field test performed on a group of eight side-by-side piles embedded 3 m in a loose sand to sustain an impact of a 6800 kg truck with an approaching velocity of 80 km/h. The instrumentation includes accelerometers on the truck, strain gauges on the posts, and high-speed cameras to capture the deflection. The eight posts and the connector beam have been simulated using an advanced numerical simulation software LS-DYNA (Livermore Software Technology Corporation) to characterize the features of the soil-pile-beam interaction under impact and improve the design methodology.
Hydrolysis of Dimethyl Methylphosphonate (DMMP) in Hot-Compressed Water (2020)

Dimethyl methylphosphonate (DMMP) is often used as a chemical surrogate for organophosphate nerve agents, as it exhibits similar physiochemical properties while having significantly lower toxicity. Continuous hydrolysis of DMMP in hot-compressed water is performed at temperatures from 200 to 300 °C, pressures of 20 and 30 MPa, and residence times from 30 to 80 s to evaluate the effects of pressure and temperature on reaction kinetics. DMMP hydrolysis is observed to follow pseudo-first-order reaction behavior, producing methylphosphonic acid and methanol as the only detectable reaction products. This is significant for the practical implementation of a continuous hydrothermal reactor for chemical warfare agent neutralization, as the process only yields stable, less-toxic compounds. Pressure has no discernible effect on the hydrolysis rate in compressed liquid water. Pseudo-first-order Arrhenius parameters are determined, with an activation energy of 90.17 ± 5.68 kJ/mol and a pre-exponential factor of 10<sup>7.51±0.58</sup> s<sup>-1</sup>.
Development of a knowledge-based intelligent decision support system for operational risk management of global supply chains (2018)

This paper proposes a knowledge-based intelligent decision support system for operational risk management of global supply chains (DSSRMG), a full-phase system not yet treated in the literature. DSSRMG predicts the supply chain performance using the enhanced artificial neural network combined with particle swarm optimisation, infers the core risk source using a method based on principle component analysis, and evaluates risk mitigation alternatives using the digraph-matrix approach combined with principle component analysis. A methodology using an adaptive-network-based fuzzy inference system is suggested to construct the knowledge base for mitigation alternatives. An industrial example is used to illustrate the performance of DSSRMG. Computational experiments show that the techniques used for DSSRMG are excellent. Especially, the algorithm for selecting the useful operation indicators improves the performance prediction accuracy by 7.1% on average. DSSRMG provides supply chain managers with a practical tool to accurately predict and effectively control the operational risk. [Received: 9 March 2017; Revised: 22 July 2017; Accepted: 2 October 2017]
Scalable Adaptive Graphics middleware for visualization streaming and collaboration in ultra resolution display environments (2008)

This paper describes the motivation and capabilities of SAGE- the scalable adaptive graphics environment- a middleware and software client for supporting ultra resolution collaboration and visualization.
The antagonistic effect of magnesium hydroxide particles on vascular endothelial activation induced by acidic PLGA degradation products (2020)

Although drug-eluting stents (DESs) are mainly coated with biodegradable polymers such as PLGA and PLLA, their acidic degradation products can alter the local microenvironment and affect the homeostasis of adjacent tissue. Previously, we developed anti-inflammatory PLGA-based materials including magnesium hydroxide (MH) to relieve the side effects caused by PLGA degradation. However, the underlying molecular mechanism of its protective effects has not yet been clarified. Here, we demonstrated the pathological mechanism of vascular endothelial activation caused by PLGA by-products. The PLGA by-products accumulated in HCAECs through MCT1, followed by oxidative stress and the activation of the MAPK/NF-κB signaling pathway. Finally, the PLGA by-products increased the expression of VCAM-1 as well as the secretion of proinflammatory cytokines. However, the addition of MH particles significantly diminished the activation of this molecular pathway and the expression of inflammation-related factors induced by acidic PLGA degradation products. Furthermore, Mg2+ released from MH particles restored endothelial function in both intracellular and extracellular spaces. Taken together, MH particles prevent the accumulation of PLGA degradation products in HCAECs, thereby repressing the associated vascular endothelial activation. These findings on the biochemical mechanisms are expected to provide important clues for addressing the safety issues in nearly all biodegradable polymer-based implants.
DSP architecture for cochlear implants (2006)

This paper describes low-power DSP architecture for use in cochlear implants. The microsystem, fabricated in TSMC 0.18mum CMOS, consumes 1.79mW from a 1.2V supply and occupies an area of 9.18mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2 </sup> while providing the necessary programmability for high speech comprehension by patients. Standby power consumption is 330muW
Study of the Effects of Different Substances on the Early Stages of Papillary Stone Formation (1996)

We have studied the early stages of calcium oxalate monohydrate (COM) crystallization, mainly heterogeneous nucleation, on fixed particles. Experiments were performed using a flow system that closely simulates the human renal conditions related to COM heterogeneous nucleation. The effects of citrate, phytate, aescin and glycyrrhinic acid in the COM heterogeneous nucleation on different solid surfaces as calcium phosphate, a mixture of mucin and calcium phosphate and wax were studied. The presence of citrate at normal urinary concentrations (1.85.10(-3) M) totally inhibited the development of COM crystals only on the most hydrophobic assayed material (wax). Saponins (aescin and glycyrrhinic acid) only exhibited important inhibitory effects of COM crystallization on the hydrophobic wax substrate but in no case the formation of COM crystals was totally prevented. Phytate exerted the most remarkable effects on the heterogeneous nucleation of COM crystals, thus, when it was present at 1.43.10(-7) M, it totally prevented the development of COM crystals on the three assayed solid substrates.
Novel deep-blue emitting phosphorescent emitter (2005)

Currently, one of the most challenging applications for OLEDs is the full color display. The most energy-efficient way to realize light generation in OLEDs is by using phosphorescent emitters. Green and red emitters have already been demonstrated, but the search for blue emitting organic phosphorescent emitters with good color purity is still ongoing with arduous effort. Here we present our work with a new material developed at BASF which allows phosphorescent emission in the deep-blue spectral range. The emitter has an emission maximum at 400 nm, which gives CIE color coordinates of x = 0.16 and y = 0.06. An OLED device made with this new material shows a maximum external quantum efficiency of 1.5 %. The OLED was built in a three layer structure, with the emitting zone being a hybrid guest-host system. As host material we used the optically and electronically inert polymer poly-methyl-methacrylate (PMMA). Because of its lack of charge transport abilities we doped the host material with a high concentration of the triplet emitting material, i.e. the emitter itself is also used as charge transport material.
Effect of SARS-CoV-2 Infection and Infection Severity on Longer-Term Glycemic Control and Weight in People With Type 2 Diabetes (2022)

In a multicenter cohort of patients in the U.S. with preexisting T2D, there was no significant change in longer-term average HbA1c or weight among patients who had COVID-19. Mechanical ventilation was associated with a decrease in HbA1c after COVID-19.