gebhart/patrepeval huggingface dataset:
Bacteriorhodopsin: a natural, efficient (nonlinear) photonic crystal (2001)

From the angular dependence of the second-order nonlinear light scattering (hyper-Rayleigh scattering) from a suspension of purple membrane, bacteriorhodopsin was recently shown to exhibit (nonlinear) photonic crystal properties [Opt. Lett.25, 1391 (2000)]. The optical nonlinearity, i.e., the first hyperpolarizability β, is localized in the small retinal moiety, whereas the optically linear refractive index n is relevant to the large membrane protein. The combination of the nonlinear hyperpolarizability of the retinal decoupled from the linear refractive index of the protein explains the observed angular dependence. The temporal evolution of this angular dependence has now been analyzed. The disappearance of the angular dependence of the nonlinear scattering is shown to be a consequence of the solubilization of the large purple membrane patches into individual protein monomers. This result strongly suggests that decoupling of the optical nonlinearity from the phase-matching condition for coherent second-harmonic generation will result in highly efficient coherent second-harmonic generation in bacteriorhodopsin crystals. In addition, a simulation of the bandgap properties was made for an abstracted structure with a large refractive index for the retinal and with a small refractive index for the protein matrix.
DOCSIS 3.1: Scaling Broadband Cable to (2015)

The cable industry has recently released the DOCSIS® 3.1 specifications which are the fifth generation of the DOCSIS family of specifications. In this article, we introduce the building blocks of DOCSIS 3.1 and highlight the specific capabilities that will help broadband cable systems scale to support gigabit-per- second network speeds. While this article is a tutorial on DOCSIS 3.1, an important objective is to engage and motivate the academic community to participate in research related to emerging DOCSISbased cable systems. We identify a set of open issues that represent challenges and opportunities for academic researchers to explore.
High-Endurance (>1011cycles) and Thermally-Stable Sub-100nm TiO2 Channel FeFET for Low-Power Memory Centric 3D-LSI Applications (2023)

We present high-performance and highly-reliable HfO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> -based ferroelectric FETs (FeFETs) using thermally-stable TiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> channels. Our device with the channel length <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$&lt; 100\text{nm}$</tex> showed high-speed and low-voltage program/erase <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$(100\mathrm{n}\sec/\pm 3\mathrm{V})$</tex> . We also confirmed whole-channel switching, which overcomes the difficulty in erase operation of n-type oxide semiconductor channel FeFETs. Furthermore, excellent endurance over <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">$10^{11}$</tex> cycles is demonstrated, making TiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> -FeFET promising candidate for future low-power memory centric 3D-LSI applications.
Pseudohyperparathyroidism in a mare associated with squamous cell carcinoma of the vulva. (1990)

An 18-year-old Appaloosa mare was examined because of squamous cell carcinoma of the vulva, anorexia with pronounced weight loss, and hypercalcemia. The tumor had developed rapidly over a period of 3 months and externally extended ventrally involving the perineum and the dorsal aspect of the udder. Necropsy examination demonstrated a large primary squamous cell carcinoma of the vulva, perineum, and mammary gland with metastases to the supramammary, sublumbar, deep inguinal, and mediastinal lymph nodes. No gross renal lesions were observed and, histologically, there was only mild vacuolation of renal tubular epithelium. Based on the normal concentration of serum parathyroid hormone, the absence of evidence of hypervitaminosis D, and normal renal function, a diagnosis was made of hypercalcemia of malignancy or pseudohyperparathyroidism. The mechanism responsible for hypercalcemia was not determined, but the histologic type of the neoplasm and the clinical course suggested possible production of a humoral hypercalcemic factor by the neoplasm, similar to that demonstrated in certain types of human squamous cell carcinoma.
Effective photodynamic therapy against microbial populations in human deep tissue abscess aspirates (2013)

These results and the technical feasibility of advancing optical fibers through catheters at the time of drainage motivate further work on including PDT as a therapeutic option during abscess treatment.
Comparing Themes Extracted via Topic Modeling and Manual Content Analysis: Korean-Language Discussions of Dementia on Twitter (2022)

We randomly examined Korean-language Tweets mentioning dementia/Alzheimer's disease (n= 12,413) posted from November 28 to December 9, 2020, without limiting geographical locations. We independently applied Latent Dirichlet Allocation (LDA) topic modeling and qualitative content analysis to the texts of the Tweets. We compared the themes extracted by LDA topic modeling to those identified via manual coding methods. A total of 16 themes were detected from manual coding, with inter-rater reliability (Cohen's kappa) of 0.842. The proportions of the most prominent themes were: burdens of family caregiving (48.50%), reports of wandering/missing family members with dementia (18.12%), stigma (13.64%), prevention strategies (5.07%), risk factors (4.91%), healthcare policy (3.26%), and elder abuse/safety issues (1.75%). Seven themes whose contents were similar to themes derived from manual coding were extracted from the LDA topic modeling results (perplexity: -6.39, coherence score: 0.45). Our findings suggest that applying LDA topic modeling can be fairly effective at extracting themes from Korean Twitter discussions, in a manner analogous to qualitative coding, to gain insights regarding caregiving for family members with dementia, and our approach can be applied to other languages.
A Novel Indirect Quasi-Static Actuation Concept for 2D MEMS Micromirrors (2019)

We present a 2D MEMS raster scanning micromirror based on a novel actuation concept for the (quasi-)static axis. This is based on the distortion of the angular momentum generated by the primary resonant axis using a secondary oscillation. After introducing a model of the device dynamics using a rigid body approximation, several simulation studies are carried out to investigate the nonlinear dynamics of such a device. In the next step, a fully operational MEMS design is shown, that is actuated by piezoelectric as well as electromagnetic drive schemes. After manufacturing, we performed a series of experiments to obtain the characteristics of the resonant as well as the quasistatic axis, proving the viability of the proposed actuation concept. [2018-0250]
Ultra-Low Loss, Chip-Based Hollow-Core Waveguide Using High-Contrast Grating (2011)

Abstract : The goal of this program is to develop a chip-scale, integrated photonic platform with fiber-like losses for optical delay applications. The ability to generate long optical delays with low intrinsic loss is useful for a wide range of high precision military applications and systems including: high time-bandwidth product analog optical signal processors and delay lines for wideband RF systems, optical buffers for all-optical routing networks, and ultra-stable optical interferometers for sensing applications, e.g. rotation sensors. We report a completely new concept of chip-scale hollow-core waveguide (HCW) which eliminates dispersion and nonlinearity in typical waveguide core. We demonstrated a new waveguiding design consisting of two parallel silicon-on-insulator wafers, each containing a single layer of high-contrast subwavelength grating (HCG) to reflect light in-between. The optical confinement without any physical boundary is created by variation of HCG dimensions and demonstrated for the first time in a planar HCW with a record low loss of 0.37 dB/em. Two-dimensional light confinement in are demonstrated for both straight and curved waveguides. The unique waveguide geometry not only adds new elements into the waveguiding theory, but also will make possible costeffective manufacturing of integrated optics for chip-scale gas/fluidic sensor, athermal photonic delays lines, and lab-on-a-chip applications.
Quantification of the stimulation effect on the exocrine pancreas of two doses of secretin using MRCP (2006)

info:eu-repo/semantics/published
A new <i>O</i>-methyltransferase for monolignol synthesis in <i>Carthamus tinctorius</i> (2014)

A novel type of O-methyltransferase (OMT) cDNA was isolated from maturing seeds of Carthamus tinctorius (safflower). The deduced sequence of the OMT protein showed moderate sequence identity (52%) with C. tinctorius 5-hydroxyconiferaldehyde O-methyltransferase 1 (CAldOMT1). Phylogenetic analysis showed that the novel OMT did not belong to the typical CAldOMT [=caffeic acid OMT (CAOMT)] cluster. The recombinant protein of the OMT catalyzed 3- (or 5-) O-methylation of hydroxycinnamaldehydes and hydroxycinnamyl alcohols, while it showed only weak or moderate activity toward hydroxycinnamates and hydroxycinnamoyl coenzyme A esters. Therefore, this OMT was designated as C. tinctorius 5-hydroxyconiferaldehyde/5-hydroxyconiferyl alcohol OMT (CtAAOMT). The time profile of CtAAOMT gene expression in C. tinctorius matched the patterns of lignin accumulation. Taken together, our data strongly suggest that along with CtCAldOMT1, CtAAOMT is involved in biosynthesis of syringyl lignin.
Enriched hydrogen production by bioconversion of biodiesel waste supplemented with ferric citrate and its nano-spray dried particles (2014)

Increasing consumption of fossil fuels as well as the concern over pollution and global climate change has accelerated the development of the sustainable biofuel industry. Biodiesel, bioethanol and biomethane are already commercially available as alternatives of fossil fuels and the search for a more environmentally friendly biofuel, preferentially produced from non-food raw materials and capable of fulfilling the transportation energy requirement of the world for longer duration, is ongoing. In this context, biohydrogen produced from waste biomass is an ideal option. It has higher energy content compared to fossil and biofuels of equivalent mass and produces water as the only major emission during combustion. In the present investigation, crude glycerol (CG) generated as by-product of the biodiesel production process has been used as feedstock for biohydrogen production and different supplements have been evaluated for increasing the product yield. Nano-spray dried ferric citrate particles have been found to enhance the hydrogen production by 50.45%. Hydrogen production using extremely low CG concentration of 100 mg L−1 has been found to produce 22.7 mol-H2 per kg CG; which is 2.75-fold higher than 8.25 mol-H2 per kg CG, known for dark fermentation.
Project X: Physics Opportunities (2013)

Part 2 of "Project X: Accelerator Reference Design, Physics Opportunities, Broader Impacts". In this Part, we outline the particle-physics program that can be achieved with Project X, a staged superconducting linac for intensity-frontier particle physics. Topics include neutrino physics, kaon physics, muon physics, electric dipole moments, neutron-antineutron oscillations, new light particles, hadron structure, hadron spectroscopy, and lattice-QCD calculations. Part 1 is available as arXiv:1306.5022 [physics.acc-ph] and Part 3 is available as arXiv:1306.5024 [physics.acc-ph].
Mapping dooley graphs and commitment causality to the /spl pi/-calculus (2004)

Commitments among agents can be used to model business processes in a manner that preserves the autonomy and heterogeneity of the interacting parties. Dooley graphs are widely used in conversation-based multiagent system design. Commitments and their causal relationships can be inferred from Dooley graphs to flexibly model business processes. We present a theoretical foundation for Dooley graphs, commitments, and causality in terms of the π-calculus, a process algebra for specifying concurrent systems, which has found application in business process modeling. This paper expresses the key elements of Dooley graphs (roles, characters, conversations) and of our approach (commitments and causal diagrams) using the π-calculus. Further, we accommodate a new variety of primitives for exception handling termed reentrant connectors. The π-calculus enables us to derive useful properties from a given model and to validate its correctness. We show how these properties assist in building an entire business process model in which agents interact flexibly.
A first effort for a distributed segment-based approach on self-assembled nano networks (2013)

In this paper we present DiSR, a first effort for a distributed segment-based approach to routing and defect mapping in a nano-scale, topology agnostic scenario based on DNA self-assembly. The main aim is exploiting the already-proven qualities of segment-based routing without neither requiring a topology graph as input, nor needing a centralized algorithm to configure network paths. After introducing the conceptual elements and the execution model of DiSR, we show how the opensource Nanoxim platform has been used to evaluate the proposed approach in the process of discovering irregular network topology while establishing network segments. Results show how DiSR still preserves some important properties (coverage, defect tolerance, scalability) while avoiding centralized tree-based broadcasting and resource hungry solutions such as virtual channels and hardware redundancy. Finally, we analyzed a first, not yet optimised gate-level hardware implementation of the required control logic and storage for DiSR, demonstrating a relatively acceptable impact ranging from 10 to about 20% of the budget of transistors available for each node.
Phase-sensitivity measurement of a 10-sensor array with erbium-doped fiber amplifier telemetry (1998)

We report what are believed to be the first measurements of the phase sensitivity of a fiber sensor array using multiple low-gain remotely pumped amplifiers with an interferometric sensor inserted. The measured phase sensitivities for individual rungs average 5.7 microrad(rms)/ radicalHz and exhibit no dependence on rung number, in agreement with predictions.
Investigating Coordination in Multidegree of Freedom Control II: Correlation Analysis in 6 DOF Tracking (1997)

In these two companion papers, methods developed in a series of studies in the 1940's and 1950's are applied to the analysis of 6 DOF control devices used in modern human machine systems such as teleoperation and virtual environments. Contrary to the early studies, the current work showed that the simultaneous time on target in multidegree of freedom tracking was higher than the product of component time on target scores. The distribution of linear correlation coefficients between the tracking errors of different degrees of freedom tended to be skewed towards the positive values. These results suggested that subjects' discoordination in early multidegree of freedom tracking studies was likely due to the limitation of human machine interfaces at that time. With well designed interfaces, subjects exhibited more coordinated trials than discoordinated trials in multidegree of freedom tracking.
Downregulation of histone H2A and H2B pathways is associated with anthracycline sensitivity in breast cancer (2016)

ClinicalTrials.gov identifier NCT00003012 . Registered on 1 November 1999.
Chiral Thiol-Stabilized Silver Nanoclusters with Well-Resolved Optical Transitions Synthesized by a Facile Etching Procedure in Aqueous Solutions (2009)

A novel approach of cyclic reduction in oxidative conditions has been developed to prepare a single dominant species of chiral thiol-stabilized silver nanoclusters (AgNCs). Such AgNCs, which are stable in solution for up to a few days, have been obtained for the first time. The generality of the established procedure is proven by using several enantiomeric water-soluble thiols, including glutathione, as protective ligands. The prepared AgNCs featured prominent optical properties including a single pattern of UV-vis absorption with well-resolved peaks. The chirality of the clusters has been investigated by circular dichroism (CD) spectroscopy. CD spectra displayed strong characteristic signatures in the visible range. Tentative identification of the cluster composition is discussed.
Synthesis, Characterization, and Properties of High Molecular Weight Poly(ferrocenylgermanes) and Poly(ferrocenylsilane)−Poly(ferrocenylgermane) Random Copolymers (1996)

A series of high molecular weight poly(ferrocenylgermanes) [Fe(η-C5H3X)2GeR2]n 5a−d (X = H; a, R = Me; b, R = Et; c, R = n-Bu; d, R = Ph) and 7 (X = SiMe3, R = Me) were synthesized via the thermal ring-opening polymerization of the corresponding germanium-bridged [1]ferrocenophanes 4a−d and 6. Poly(ferrocenyldimethylsilane)−poly(ferrocenyldimethylgermane) random copolymer 8 was obtained by the thermal and transition metal-catalyzed ring-opening polymerization of a mixture of the [1]germaferrocenophane [Fe(η-C5H4)2GeMe2] (4a) and the corresponding [1]silaferrocenophane [Fe(η-C5H4)2SiMe2] (2a). The molecular weights for the homo- and copolymers were estimated by gel permeation chromatography in THF versus polystyrene standards and were found to be in the range of Mw = 5.0 × 104−2.0 × 106 and with polydispersities in the range of Mw/Mn = 1.2−2.4. A low-angle laser light scattering study of 5a in THF gave an absolute value of Mw of 3.3 × 106, which was significantly greater than the GPC estimate (Mw = 8.2 × 105). Polymer thermal transition behavior and morphology were investigated by differential scanning calorimetry (DSC) and wide-angle X-ray scattering (WAXS). Glass transitions (Tg) for the polymers were in the range of −7 to +128 °C and were found to be strongly dependent on the size and nature of the substituents attached to germanium and the substitution of the cyclopentadienyl rings. The semicrystalline nature of the poly(ferrocenyldialkylgermanes) 5a−c and the copolymer 8 was apparent from the appearance of several fairly sharp diffraction peaks in the WAXS profiles of these polymers and the presence of melt transitions (Tm) in the DSC thermograms. In contrast, polymers 5d and 7 were found to be amorphous. Cyclic voltammetry of the polymers showed the presence of two oxidation waves, which is consistent with the presence of redox coupling arising from significant interactions between the iron centers. UV/visible spectra of polymers 5a−c, 7, and 8 were measured in THF in the 350−800 nm range and were found to be consistent with an essentially localized electronic structure for the polymer backbone.
A low cost and reliable dimmable ballast topology with inherent power regulation and insensitivity to lamp characteristics (2005)

The output power of the proposed dimmable ballast topology is self-regulated and insensitive to the lamp characteristics. Accurate dimming operation with rather constant filament power can be realized simply by open loop control of the switching frequency of the converter. It can provide reliable operation during lamp ignition with fault conditions or even short circuit without the need of current sensing circuits. Prototype was built for experimental verifications. For completeness, a simple ultra low dimming method is also proposed together with the theoretical dimming limit considered.
Distributed coordination and data fusion for underwater search (2011)

This paper presents coordination and data fusion methods for teams of vehicles performing target search tasks without guaranteed communication. A fully distributed team planning algorithm is proposed that utilizes limited shared information as it becomes available, and data fusion techniques are introduced for merging estimates of the target's position from vehicles that regain contact after long periods of time. The proposed data fusion techniques are shown to avoid overcounting information, which ensures that combining data from different vehicles will not decrease the performance of the search. Motivated by the underwater search domain, a realistic underwater acoustic communication channel is used to determine the probability of successful data transfer between two locations. The channel model is integrated into a simulation of multiple autonomous vehicles in both open ocean and harbor search scenarios. The simulated experiments demonstrate that distributed coordination with limited communication significantly improves team performance versus prior techniques that continually maintain connectivity.
Binding and internalization of neurotensin in hybrid cells derived from septa1 cholinergic neurons (1995)

Autoradiographic studies from our laboratory have previously demonstrated a selective association of high affinity neurotensin (NT) binding sites with basal forebrain cholinergic neurons. In search of an in vitro model for further characterization of the role and regulation of these sites, we have examined the binding and internalization of 125I-Tyr3-NT (125I-NT) and fluorescein isothiocyanate (FITC)-conjugated NT (fluo-NT) on SN17 hybrid cells, produced by fusion of embryonic murine septal cells with neuroblastoma. 125I-NT binding to SN17 membrane preparations was specific and saturable. Scatchard analysis of the data was suggestive of an interaction with a single population of sites, the affinity (Kd = 1.7 nM) and pharmacological profile of which were comparable to those of neural NT receptors. No specific binding was observed on the parent neuroblastoma cell line, confirming that the expression of those sites is a neuronal trait. Incubation of whole SN17 cells with 125I-NT resulted in a time- and temperature-dependent internalization of the specifically bound peptide. The t1/2 of this internalization was estimated at 13 min, a value nearly identical to that reported for neurons in culture. Confocal microscopic analyses using fluo-NT indicated that the internalization process was endocytic in nature in that: 1) it was entirely blocked by the endocytosis inhibitor phenylarsine oxide; and 2) it was mediated through small intracytoplasmic particles the size and maturation of which corresponded to that of endosomes. It is proposed that the expression and internalization of NT receptors by SN17 hybrid cells represent a new facet of these cells' cholinergic phenotype that makes them amenable to the study of NT interactions with cholinergic cells.
Transrenal bare stents in endovascular treatment of abdominal aortic aneurysms. (2002)

Endovascular stent-graft (EVSG) repair of abdominal aortic aneurysms (AAA) has continued to evolve since its introduction in 1991. The ability to secure a stent-graft in the suprarenal aorta with an uncovered proximal stent is felt by many to improve the overall fixation of the device and decrease the risk of migration and endoleak. While preliminary evidence suggests that type I endoleaks may be less frequent when transrenal bare stents are used, this has yet to be conclusively shown. Of obvious concern is the risk of renal parenchymal damage or diminished blood flow following placement of a bare stent across the renal artery ostia. Numerous small series have shown little or no risk of significant renal impairment at intermediate length of follow-up after transrenal stent placement. The presence of a stent across the renal artery orifice does not appear to interfere with later interventions on that artery, such as angioplasty and stenting.
Fibroid Embolization: Periprocedural Care (2000)

This article outlines aspects of patient recruitment periprocedural and postprocedural care. Important aspects of business management, preprocedure evaluations, indications, and postprocedure management are discussed.