gebhart/patrepeval huggingface dataset:
Automatic Application-Specific Calibration to Enable Dynamic Voltage Scaling in FPGAs (2018)

Dynamic voltage scaling (DVS) is one of the most effective ways to reduce integrated circuit power. However, the programmability of field programmable gate arrays (FPGAs) means that the critical paths depend on the application configured into the FPGA and this makes DVS more difficult. We propose a DVS technique that is able to determine the minimum safe V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">dd</sub> of any application for each FPGA chip. For each application, we create multiple calibration bit-streams that are used to generate a calibration table (CT), which stores the actual failing points of that application on a specific FPGA, under various operating conditions. This CT is used to scale V <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">dd</sub> while the application is running to guarantee safe operation with minimal power consumption. We develop an automated tool (FRoC) that ensures a fast-robust-calibration of the FPGA to any application using it. FRoC makes the calibration process invisible to FPGA users, does not add any extra manual steps to the design process, and uses novel algorithms to minimize the extra flash storage requirements for calibration. Our results show that across a large suite of benchmarks the calibration process requires a geomean of less than four bit-streams and our DVS technique achieves a 33% total power reduction on two large applications.
[Exome sequencing revealed Allan-Herndon-Dudley syndrome underlying multiple disabilities]. (2014)

Normal function of the thyroid gland is the cornerstone of a child's mental development and physical growth. We describe a Finnish family, in which the diagnosis of three brothers became clear after investigations that lasted for more than 30 years. Two of the sons have already died. DNA analysis of the third one, a 16-year-old boy, revealed in exome sequencing of the complete X chromosome a mutation in the SLC16A2 gene, i.e. MCT8, coding for a thyroid hormone transport protein. Allan-Herndon-Dudley syndrome was thus shown to be the cause of multiple disabilities.
A study on the characteristics and pervaporation performance of polyamide thin‐film composite membranes with modified polyacrylonitrile as substrate for bioethanol dehydration (2013)

Abstract To improve the pervaporation performance in separating an aqueous ethanol solution, polyamide thin‐film composite ( TFC ) membranes ( m ‐tolidine‐H‐ TMC / mPAN ) were prepared through the interfacial polymerization reaction between trimesoyl chloride ( TMC ) and 2,2'‐dimethylbenzidine hydrochloride ( m ‐tolidine‐H) on the surface of a modified polyacrylonitrile ( mPAN ) membrane. The effects of the feed ethanol concentration on the pervaporation performance and the durability of m ‐tolidine‐H‐ TMC / mPAN TFC membranes were investigated. To choose the optimal mPAN membrane as the TFC substrate, the effect of hydrolysis time on the chemical properties and separation performance of an mPAN substrate was also studied. An appropriate hydrolysis time of 15 min was chosen to obtain the mPAN substrate due to the corresponding high permeation flux. The m ‐tolidine‐H‐ TMC / mPAN TFC membrane exhibited a high pervaporation performance for ethanol dehydration. A positron annihilation lifetime spectroscopy experiment was used to estimate the mean free‐volume radius of the m ‐tolidine‐H‐ TMC polyamide selective layer, which lay between the radii of the water and ethanol molecules. © 2013 Society of Chemical Industry
NMR phosphorus spectroscopy at 9.4 Tesla using construted Quadrature surface coil (2012)

The energy supply in cells is provided by molecules that contain phosphorus. Especially phosphocreatine (PCr) and adenosine triphosphate (ATP) are phosphorus metabolites that carry the energy needed for most processes in the brain, muscles and other organs. Magnetic Resonance Spectroscopy has the potential to quantitatively detect these substances in living subjects noninvasively. For routine applications, however, 31P MRS suffers from its low SNR due to the low concentration of 31P metabolites and the reduced Larmor frequency compared to protons. Using an ultra-high field of 9.4 T for 31P MRS is expected to yield significantly higher SNR and thus has the potential to make this technique a valuable tool in clinical and scientific examinations.
Search for Higgs bosons decaying toaain theμμττfinal state inppcollisions ats=8  TeVwith the ATLAS experiment (2015)

A search for the decay to a pair of new particles of either the 125 GeV Higgs boson (h) or a second charge parity (CP)-even Higgs boson (H) is presented. The data set corresponds to an integrated luminosity of 20.3 fb -1 of pp collisions at ffiffi ffi s p 8 TeV recorded by the ATLAS experiment at the LHC in 2012. The search was done in the context of the next-to-minimal supersymmetric standard model, in which the new particles are the lightest neutral pseudoscalar Higgs bosons (a). One of the two a bosons is required to decay to two muons while the other is required to decay to two leptons. No significant excess is observed above the expected backgrounds in the dimuon invariant mass range from 3.7 to 50 GeV. Upper limits are placed on the production of h aa relative to the standard model gg h production, assuming no coupling of the a boson to quarks. The most stringent limit is placed at 3.5% for m a 3.75 GeV. Upper limits are also placed on the production cross section of H aa from 2.33 to 0.72 pb, for fixed m a 5 GeV with m H ranging from 100 to 500 GeV.
Immobilization of hazardous and radioactive wastes into glass structures (1997)

As a result of more than three decades of international research, glass has emerged as the material of choice for immobilization of a wide range of potentially hazardous radioactive and non-radioactive materials. The ability of glass structures to incorporate and then immobilize many different elements into durable, high integrity, waste glass products is a direct function of the unique random network structure of the glassy state. Every major country involved with long-term management of high-level radioactive waste (HLW) has either selected or is considering glass as the matrix of choice for immobilizing and ultimately, disposing of the potentially hazardous, high-level radioactive material. There are many reasons why glass is preferred. Among the most important considerations are the ability of glass structures to accommodate and immobilize the many different types of radionuclides present in HLW, and to produce a product that not only has excellent technical properties, but also possesses good processing features. Good processability allows the glass to be fabricated with relative ease even under difficult remote-handling conditions necessary for vitrification of highly radioactive material. The single most important property of the waste glass produced is its ability to retain hazardous species within the glass structure and this is reflected by its excellent chemical durability and corrosion resistance to a wide range of environmental conditions.
Direct laser writing of liquid metal grids for visually imperceptible stretchable electronics (Conference Presentation) (2019)

Optically clear and elastic conductors are critical for the next generation of fully imperceptible stretchable electronics that are not only optically transparent, but also invisible under typical lighting conditions and reading distances. Such conductors have a central role in a wide range of emerging applications such as wearable computing, soft bioelectronics, and biologically-inspired robotics. Here, we introduce a materials architecture and laser-based microfabrication technique to produce electrically conductive circuitry (sheet resistance = 2.95 Ω/sq; conductivity = 5.65×105 S/m) that are soft, elastic (strain limit > 100%), and optically transparent. The circuitry is composed of a grid-like array of visually imperceptible liquid metal (LM) lines on a clear elastomer. The laser fabrication approach allows for fully imperceptible electronics that have not only high optical transmittance (>85% at 550 nm) but also are invisible under typical lighting conditions and reading distances. This unique combination of properties is enabled by using a direct laser writing technique that results in LM grid patterns with a line width and pitch as small as 4.5 μm and 100 μm, respectively – yielding grid-like wiring on a transparent polydimethylsiloxane (PDMS) elastomer substrate that has adequate conductivity for digital functionality but is also well below the threshold for visual perception. The fabricated LM wiring can be readily interfaced with conventional circuit components (e.g., lead wiring, or LED chips) to enable optically clear digital electronics. The electrical, mechanical, electromechanical, and optomechanical characterization of fabricated LM circuits shows that the high conductivity and transparency are preserved at tensile strains of ~100%.
Distinct signals and immune cells drive liver pathology and glomerulonephritis in ABIN1[D485N] mice (2019)

We report that TLR7, IL-6, and the adaptive immune system are essential for autoimmunity and glomerulonephritis but not for liver pathology in mice expressing the ubiquitin-binding-defective ABIN1[D485N] mutant. The blood and organs of ABIN1[D485N] mice have exceptionally high numbers of patrolling monocytes (pMo), which develop independently of IL-6 and the adaptive immune system. They are detectable in the blood months before autoimmunity and organ pathology are seen and may have diagnostic potential. The splenic pMo, inflammatory monocytes (iMo), and neutrophils of ABIN1[D485N] mice expressed high levels of mRNAs encoding proteins released during NETosis, which together with the high numbers of monocyte-derived dendritic cells (MoDCs) may drive the liver pathology in ABIN1[D485N] mice, and contribute to the pathology of other organs. The splenic iMo of ABIN1[D485N] mice displayed high expression of mRNAs encoding proteins controlling cell division and were actively dividing; this may underlie the increased pMo and MoDC numbers, which are derived from iMo. An orally active IRAK4 inhibitor suppressed all facets of the disease phenotype and prevented the increase in pMo numbers.
A new polymorphic probe on chromosome 3p: λLIB4–59 (D3S575) (1991)

XLIB4-59 is a 1.9 kb EcoRI fragment isolated from a Charon 21A human chromosome 3 library (1). Polymorphism: Both MspI and Null digestions of genomic DNA and hybridization with the probe detects a two-allele polymorphism: 13.0 kb (Al), 10.5 kb (A2), 10.5 kb (B1) and 6.6 kb (B2). Frequency: Estimated from 120 unrelated Caucasians A1:0.36 B1:0.
Mixed resolution coding with inter view prediction for mobile 3DTV (2010)

This paper presents results on mixed resolution stereo video coding including inter view prediction. The objective tests show that coding one view of a stereo pair at a lower resolution outperforms coding of a low pass filtered view at base resolution. For both coding methods inter view prediction produces additional coding gains. Two different prediction approaches have been compared: One uses the lower resolution view as base view, which is used to predict the second view, the other uses the higher resolution view as base view. The prediction is realized by up-sampling or down-sampling the decoded base view before predicting. It turned out that equal results are achieved for low bit rates, while predicting from high resolution to low resolution view performs better for medium and high bit rates. During coding, different QP combinations for left and right view have been compared to achieve the maximum combined PSNR.
A superconductor high-resolution ADC (2001)

This paper presents the development of an Analog-to-Digital Converter (ADC) based on a low-temperature superconductor (Nb) chip and room-temperature interface modules for applications in digital receivers for communications, radars, and electronic warfare. The ADC design, MATLAB/sup TM/ simulations, and experimental results of single- and two-tone tests are described.
Timing-Jitter Reduction by Use of a Spectral Filter in a Broadband Femtosecond Fiber Laser (2015)

We demonstrate an experimental reduction of timing jitter in a nonlinear-polarization-evolution-based passively mode-locked fiber laser. This laser operates on the stretched pulse regime at 201 MHz repetition rate. By incorporating a proper bandpass filter (BPF) into the cavity, the effect of the BPF on pulse output characteristics is investigated. The timing jitter of the output pulse is reduced significantly from 29.9 to 17.4 fs (both integrated within 1 kHz-10 MHz) and the full-width at half-maximum is >60 nm. This high repetition rate, low timing jitter, broadband fiber laser could be an excellent candidate for high-speed, and high-resolution photonic analog-to-digital conversion system.
Linkage of Crohn’s disease-related serological phenotypes: NFKB1 haplotypes are associated with anti-CBir1 and ASCA, and show reduced NF-κB activation (2008)

These results suggest that NFKB1 haplotypes induce dysregulation of innate immune responses by altering NF-kappaB expression. The results also show the use of EBV-transformed lymphoblastoid cell lines to conduct phenotypic studies of genetic variation.
Structure−Activity Relationships of 4-Hydroxy-3-nitroquinolin-2(1H)-ones as Novel Antagonists at the Glycine Site of N-Methyl-d-aspartate Receptors (1996)

A series of 4-hydroxy-3-nitroquinolin-2(1H)-ones (HNQs) was synthesized by nitration of the corresponding 2,4-quinolinediols. The HNQs were evaluated as antagonists at the glycine site of NMDA receptors by inhibition of [3H]DCKA binding to rat brain membranes. Selected HNQs were also tested for functional antagonism by electrophysiological assays in Xenopus oocytes expressing either 1a/2C subunits of NMDA receptors or rat brain AMPA receptors. The structure-activity relationships (SAR) of HNQs showed that substitutions in the 5-, 6-, and 7-positions in general increase potency while substitutions in the 8-position cause a sharp reduction in potency. Among the HNQs tested, 5,6,7-trichloro HNQ (8i) was the most potent antagonist with an IC50 of 220 nM in [3H]DCKA binding assay and a Kb of 79 nM from electrophysiological assays. Measured under steady-state conditions HNQ 8i is 240-fold selective for NMDA over AMPA receptors. The SAR of HNQs was compared with those of 1,4-dihydroquinoxaline-2,3-diones (QXs) and 1,2,3,4-tetrahydroquinoline-2,3,4-trione 3-oximes (QTOs). In general, HNQs have similar potencies to QXs with the same benzene ring substitution pattern but are about 10 times less active than the corresponding QTOs. HNQs are more selective for NMDA receptors than the corresponding QXs and QTOs. The similarity of the SAR of HNQs, QXs, and QTOs suggested that these three classes of antagonists might bind to the glycine site in a similar manner. With appropriate substitutions, HNQs represent a new class of potent and highly selective NMDA receptor glycine site antagonists.
Estimation and equalization of fading channels with random coefficients (2002)

The time-varying tap coefficients of frequency selective fading channels are typically modeled as random processes with low-pass power spectra. However, traditional adaptive techniques usually make no assumption on the channel's time variations and hence do not exploit this information. Kalman filtering methods are derived to track the channel by employing a multichannel autoregressive description of the time-varying taps in a decision-feedback equalization framework. Fitting a model to the variations of the channel's taps is a challenging task because the tap coefficients are not observed directly. A novel linear method is proposed in order to estimate the model parameters from input/output data. The consistency of the proposed method is shown, and some illustrative simulations are presented.
Half Direct-Link Setup (H-DLS) for Fairness between External and Local TCP Connections in IEEE 802.11e Wireless LANs (2007)

The IEEE 802.11e standard supports a direct-link setup (DLS) mechanism optionally to improve the throughput. Using this mechanism, IEEE 802.11e stations in proximity can directly exchange frames with no intervention of an access point. However, extensive simulations reveal the severe unfairness between external and local TCP connections in the IEEE 802.11e DLS mode due to the characteristics of TCP: a window-based flow control mechanism. This paper first analyzes why a fairness problem happens between external and local TCP connections in the IEEE 802.11e DLS mode. Then, we seeks to achieve fairness between them by introducing a novel mechanism dubbed half direct-link setup plus (H-DLS) which differentiates the paths for TCP DATA and ACK packets of local TCP connections. Simulation results reveal that H-DLS achieves the fairness between external and local TCP connections while keeping the aggregate throughput higher than the original IEEE 802.11 infrastructure.
Low‐Power Radiofrequency Application and Intracardiac Echocardiography for Creation of Continuous Left Atrial Linear Lesions (1999)

Long linear lesions can be safely and effectively performed in the canine left atrium, using a tip-deflectable multielectrode catheter. Intracardiac echocardiography may be helpful for positioning the ablation catheter in some parts of the left atrium, and preablation parameters, especially a nontraumatic low-power RF application, are able to predict ultimate lesion creation with high accuracy.
Polydimethylsiloxane quenchable vitrimers (2017)

Reprocessable and recyclable PDMS vitrimers can be transformed into “quenched” vitrimers that exhibit conventional elastomer properties.
Ultrafast diffractive optical micro-trap arrays for neutral atom quantum computing (2012)

We design and fabricate arrays of diffractive optical elements (DOEs) to realize neutral atom micro-traps for
quantum computing. We initialize a single atom at each site of an array of optical tweezer traps for a customized
spatial configuration. Each optical trapping volume is tailored to ensure only one or zero trapped atoms.
Specifically designed DOEs can define an arbitrary optical trap array for initialization and improve collection
efficiency in readout by introducing high-numerical aperture, low-profile optical elements into the vacuum
environment.
We will discuss design and fabrication details of ultra-fast collection DOEs integrated monolithically and coaxially
with tailored DOEs that establish an optical array of micro-traps through far-field propagation. DOEs, as mode
converters, modify the lateral field at the front focal plane of an optical assembly and transform it to the desired field
pattern at the back focal plane of the optical assembly. We manipulate the light employing coherent or incoherent
addition with judicious placement of phase and amplitude at the lens plane. This is realized through a series of
patterning, etching, and depositing material on the lens substrate. The trap diameter, when this far-field propagation
approach is employed, goes as 2.44λF/#, where the F/# is the focal length divided by the diameter of the lens
aperture. The 8-level collection lens elements in this presentation are, to our knowledge, the fastest diffractive
elements realized; ranging from F/1 down to F/0.025.
Chemical Constituents from Croton insularis (2005)

Abstract Three new clerodane‐type terpenoids, furocrotinsulolide A ( 1 ), furocrotinsulolide B ( 2 ), and crotinsulactone ( 3 ), as well as a new phenolic disaccharide ( 4 ) have been isolated from the aerial parts of Croton insularis , together with eight known compounds. Their structures were established by in‐depth 1D‐ and 2D‐NMR spectroscopy, mass spectroscopy, and quantum‐mechanical calculations.
Flash vacuum pyrolysis of sulphonyl stabilised phosphorus ylides: generation and reactivity of sulphonyl carbenes (1991)

Thermal decomposition of arylmethylsulphonylalkylidenetriphenylphosphoranes results in loss of Ph3P and SO2 to give alkenes and in some cases products derived from benzylic radicals, the products are explained by a mechanism involving sulphonyl carbenes.
Census of new geophysical employees and geophysics graduates (1976)

Abstract During the 1975 SEG Academic-Industry Seminar held in Houston, June 22-26, participants asked for statistical data regarding the employment of university graduates as geophysics. Accordingly, a questionnaire was sent to about 75 companies which employ geophysicist: oil companies, geophysical contractors, etc. The following tabulation details the result of the 31 questionnaire returned by December 20, 1975. Three questions were asked one regarding employees hired directly from universities, a second regarding summer employees, and third regarding requirements for foreign languages. The last question was designed to obtain information for a study being conducted for the AAAS.
Methylation of Histone H3 by Set2 in Saccharomyces cerevisiae Is Linked to Transcriptional Elongation by RNA Polymerase II (2003)

Set2 methylates Lys36 of histone H3. We show here that yeast Set2 copurifies with RNA polymerase II (RNAPII). Chromatin immunoprecipitation analyses demonstrated that Set2 and histone H3 Lys36 methylation are associated with the coding regions of several genes that were tested and correlate with active transcription. Both depend, as well, on the Paf1 elongation factor complex. The C terminus of Set2, which contains a WW domain, is also required for effective Lys36 methylation. Deletion of CTK1, encoding an RNAPII CTD kinase, prevents Lys36 methylation and Set2 recruitment, suggesting that methylation may be triggered by contact of the WW domain or C terminus of Set2 with Ser2-phosphorylated CTD. A set2 deletion results in slight sensitivity to 6-azauracil and much less beta-galactosidase produced by a reporter plasmid, resulting from a defect in transcription. In synthetic genetic array (SGA) analysis, synthetic growth defects were obtained when a set2 deletion was combined with deletions of all five components of the Paf1 complex, the chromodomain elongation factor Chd1, the putative elongation factor Soh1, the Bre1 or Lge1 components of the histone H2B ubiquitination complex, or the histone H2A variant Htz1. SET2 also interacts genetically with components of the Set1 and Set3 complexes, suggesting that Set1, Set2, and Set3 similarly affect transcription by RNAPII.
Editorial: Recent Developments in Haploidentical Hematopoietic Cell Transplantation: Therapy and Complications (2021)

EDITORIAL article Front. Immunol., 17 August 2021Sec. Alloimmunity and Transplantation Volume 12 - 2021 | https://doi.org/10.3389/fimmu.2021.746221
Thermally active 4&#x00D7;4 non-blocking switch for networks-on-chip (2008)

We demonstrate power penalty measurements through two output ports of a 4times4 nonblocking switch designed for networks-on-chip. We use integrated metal heaters to tune individual rings, and observe how the device scales with data rate.
Incentive Networks (2006)

We consider a setting in which users seeking information or services can pose queries, together with incentives for answering them, that are propagated along paths in a network. This type of information-seeking process can be formulated as a game among the nodes in the network, and this game has a natural Nash equilibrium. In such systems, it is a fundamental question to understand how much incentive is needed in order for a node to achieve a reasonable probability of obtaining an answer to a query from the network. We study the size of query incentives as a function both of the rarity of the answer and the structure of the underlying network. This leads to natural questions related to strategic behavior in branching processes. Whereas the classically studied criticality of branching processes is centered around the region where the branching parameter is 1, we show in contrast that strategic interaction in incentive propagation exhibits critical behavior when the branching parameter is 2.