gebhart/patrepeval huggingface dataset:
EUV processing investigation on state of the art coater/developer system (2011)

In order to further understand the processing sensitivities of the EUV resist process, TEL and imec have continued their collaborative efforts. For this work, TEL has delivered and installed the state of the art, CLEAN TRACK&trade; LITHIUS Pro&trade; -EUV coater/developer to the newly expanded imec 300mm cleanroom in Leuven, Belgium. The exposures detailed in this investigation were performed off-line to the ASML EUV Alpha Demo Tool (ADT) as well as on the inline ADT cluster with CLEAN TRACK&trade; ACT&trade; 12 coater/developer. As EUV feature sizes are reduced, is it apparent that there is a need for more precise processing control, as can be demonstrated in the LITHIUS Pro&trade; -EUV. In previous work from this collaboration1, initial investigations from the ACT&trade; 12 work showed reasonable results; however, certainly hardware and processing improvements are necessary for manufacturing quality processing performance. This work continues the investigation into CDU and defectivity performance, as well as improvements to the process with novel techniques such as advanced defect reduction (ADR), pattern collapse mitigation with FIRM&trade;Extreme and resolution improvement with tetrabutylammoniumhydroxide (TBAH).
Structure of the Nonclassical 7-Norbornenyl Cation1 (1966)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructure of the Nonclassical 7-Norbornenyl Cation1M. Brookhart, Arthur Diaz, and S. WinsteinCite this: J. Am. Chem. Soc. 1966, 88, 13, 3135–3136Publication Date (Print):July 1, 1966Publication History Published online1 May 2002Published inissue 1 July 1966https://pubs.acs.org/doi/10.1021/ja00965a046https://doi.org/10.1021/ja00965a046research-articleACS PublicationsRequest reuse permissionsArticle Views643Altmetric-Citations35LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Sampling plan optimization for critical dimension metrology (2006)

To enhance the quality of Advanced Process Control (APC), the optimization of the sampling plan in critical dimension (CD) metrology is studied through empirical considerations concerning the characteristics of errors and a statistical approach. The metric of the optimization is the accuracy of lot mean estimation. Critical dimension errors are classified into static and dynamic errors. A static error is defined as an error that repeats through lots while keeping its tendency, and a dynamic error as an error whose tendency changes by lot. In the basic concept of our sampling plan, sampling positions and size are determined from the static error and dynamic error, respectively. The balance of the sampling number of the wafer, field, and site under the restriction of total sampling size is optimized by a statistical theory.
Chemotherapy for non-small cell lung cancer (1995)

A meta-analysis suggests that the benefits are small

For some cancers, treatments are so effective that the question of whether to treat does not arise. For many others, however, while gratifying responses sometimes occur, there are also substantial toxicities related to treatment, and benefits of any kind may be small. The toxicities, inconvenience, and expense of chemotherapy are endured by both patients whose tumours do and do not respond. When faced with such imperfect treatments, clinical trialists must determine, within the limitations of biological variability, whether these treatments result in statistically significant benefits and at what cost. Doctors thenhave to decide whether these benefits are clinically important and whether they outweigh potential risks for a particular patient.

With the relatively small absolute survival benefits observed for chemotherapy of non-small cell lung cancer, large numbers of patients are required to draw conclusions with confidence. In this issue of the Journal Albertini et al report the results of a meta-analysis of updated data from 9387 patients participating in 52 randomised clinical trials comparing chemotherapy with no chemotherapy …
Serum endostatin levels are associated with diffusion capacity and with tuberous sclerosis- associated lymphangioleiomyomatosis (2019)

Endostatin is a naturally occurring collagen fragment with anti-angiogenic properties. We investigated the association between serum endostatin levels and DLCO in a cohort of patients with lymphangioleiomyomatosis (LAM). Associations of endostatin levels to clinical features of LAM were explored using logistic regression models. Endostatin levels were associated with DLCO and were higher in subjects with TSC-associated LAM compared to sporadic LAM. These data suggest that endostatin could be a predictive biomarker of decline in DLCO and that germline mutational inactivation of the TSC1 or TSC2 gene is associated with higher endostatin levels. These findings could offer novel insights into the pathogenesis of LAM.
Mechanism of photosubstitution of (.eta.5-C5H5)2Fe2(CO)4 by triphenylphosphine and triisopropyl phosphite. Direct observation of a binuclear intermediate, (.eta.5-C5H5)2Fe2(CO)4{P[OCH(CH3)2]3}, a molecule with a carbonyl bridge but no metal-metal bond (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMechanism of photosubstitution of (.eta.5-C5H5)2Fe2(CO)4 by triphenylphosphine and triisopropyl phosphite. Direct observation of a binuclear intermediate, (.eta.5-C5H5)2Fe2(CO)4{P[OCH(CH3)2]3}, a molecule with a carbonyl bridge but no metal-metal bondDavid R. Tyler, Maryke A. Schmidt, and Harry B. GrayCite this: J. Am. Chem. Soc. 1979, 101, 10, 2753–2755Publication Date (Print):May 1, 1979Publication History Published online1 May 2002Published inissue 1 May 1979https://pubs.acs.org/doi/10.1021/ja00504a056https://doi.org/10.1021/ja00504a056research-articleACS PublicationsRequest reuse permissionsArticle Views126Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Thin film measurement system for moving objects based on a laterally distributed linear variable filter spectrometer (2012)

Instantaneous measurement of optical or geometrical parameters of thin layers is an ambitious aim in many industrial applications. These layers have a variety of use-cases, such as optical bandpassing, dielectric permittivity, or lubrication. Mostly, these layers are in motion due to the production process. In order to observe process parameters, the motion usually has to be disrupted. Thus, the increase of production time due to control purposes is an undesirable drawback of this otherwise suitable technique. In this publication, we present a solution to this particular drawback of most production process monitoring systems exemplarily for film thickness measurement. We show the realization of a measurement principle which has, to our knowledge, never been published before in this application. Therefore, we exploit the advantages of the combination of a linear variable filter with a complementary metal oxide semiconductor sensor array. By an apt readout sequence, this measurement system is able to measure transmission spectra while the target is in motion. We show that this measurement system is able to measure film thicknesses of objects in the range of several 100 nm thickness at up to a velocity of 4 m/s. A reproducibility below 2 nm was acquired.
<title>Optical Monte Carlo transport in scintillators</title> (1999)

To facilitate the design and characterization of scintillation detectors we are implementing a new Monte Carlo code. The code handles the transport of optical photons through plastic scintillators, and is being written to ensure accurate interaction of photons at surfaces and to allow an analysis of photon arrival times at the detector entrance window. The code is being written in C++ with the long term view of forming an extension to the EGS4/5<SUP>1</SUP> code system. This paper will discuss the implementation of the code, outlining the means by which geometry is specified and how photon interactions have been modelled.
Online Training and Sanitization of AD Systems (2007)

In this paper, we introduce novel techniques that enhance the training phase of Anomaly Detection (AD) sensors. Our aim is to both improve the detection performance and protect against attacks that target the training dataset. Our approach is two pronged: we employ a novel sanitization method for large training datasets that removes attacks and traffic artifacts by measuring their frequency and position inside the dataset. Furthermore, we extend the training phase in the spatial dimension to include model information from other collaborative systems. We demonstrate that by doing so we can protect all the participating systems against targeted training attacks. Another aspect of our system is its ability to adapt and update the normality model when there is a shift in the nature of inspected traffic that reflects actual changes in the back-end servers. Such "on-line" training appears to be the "Achilles' heel" of AD sensors because they fail to adapt when there is a legitimate deviation in the traffic behavior, thereby flooding the operator with false positives. To counter that, we discuss the integration of what we call a shadow sensor with the AD system. This sensor complements our techniques by acting as an oracle to analyze and classify the resulting "suspect data" identified by the AD sensor. We show that our techniques can be applied to a wide range of unmodified AD sensors without incurring significant additional computational cost beyond the initial training phase.
Context-Based Fractional Sample Refinement for HEVC Compliant Encoding (2016)

The H.265/MPEG-H High Efficiency Video Coding compliant encoding process faces the challenge of high computational complexity. Particularly, in the case of inter-picture prediction, most of the computational resources are allocated for the motion estimation (ME) process. In turn, ME and motion compensation enable improving coding efficiency by addressing the blocks of video frames as corresponding displacements from one or more reference blocks. These displacements do not necessarily have to be limited to integer sample positions, but may have an accuracy of half sample or quarter sample positions, which are identified during fractional sample refinement. In this paper, a context-based scheme for fractional sample refinement is proposed. The scheme takes the advantage of already obtained information in prior ME steps and provides significant flexibility in terms of parameterization. In this way, it adaptively achieves a desired tradeoff between computational complexity and coding efficiency. According to the experimental results obtained for an example algorithm utilizing the proposed framework, a significant decrease in the number of search points can be achieved. For instance, considering only 6 instead of 16 fractional sample positions results in a tradeoff of only 0.4% Bjøntegaard Delta-rate loss for high-definition video sequences compared with the conventional interpolation-and-search method.
Enhancement of the Water Adsorptivity of Metal–Organic Frameworks upon Hybridization with Layered Double Hydroxide Nanosheets (2017)

Efficient water adsorbents with improved hydrostability can be synthesized by the hybridization of metal–organic framework (MOF) compounds with exfoliated layered double hydroxide (LDH) 2D nanosheets. The self-assembly between copper benzene tricarboxylate (Cu-BTC) MOF nanocrystals and exfoliated Mg–Al-LDH nanosheets leads to the nanoscale mixing of the MOF and LDH components, as well as to the prevention of the formation of aggregated secondary MOF particles. In the resulting nanohybrids, spherical Cu-BTC nanocrystals with small particle sizes of ∼5–10 nm are uniformly anchored on the surface of Mg–Al-LDH 2D nanosheets with the dimensions of several hundred nanometers. At the optimal composition, the surface area of the resulting nanohybrid becomes greater than that of pristine Cu-BTC, which is attributable to the suppression of the self-aggregation of MOF nanocrystals and to the formation of the mesoporous stacking structure of the LDH nanosheets. Of prime importance is that both the water adsorption ability and the hydrostability of Cu-BTC become notably improved upon hybridization with LDH nanosheets. The present study clearly demonstrates that exfoliated LDH nanosheets can be used as an effective hybridization matrix for exploring novel efficient MOF-based hybrid water adsorbents.
OBTURATOR INFECTED HEMATOMA AND URETHRAL EROSION FOLLOWING TRANSOBTURATOR TAPE IMPLANTATION (2004)

No AccessJournal of UrologyCLINICAL UROLOGY: Case Reports1 Apr 2004OBTURATOR INFECTED HEMATOMA AND URETHRAL EROSION FOLLOWING TRANSOBTURATOR TAPE IMPLANTATION XAVIER GAME, MARC MOUZIN, CHRISTOPHE VAESSEN, BERNARD MALAVAUD, JEAN-PIERRE SARRAMON, and PASCAL RISCHMANN XAVIER GAMEXAVIER GAME , MARC MOUZINMARC MOUZIN , CHRISTOPHE VAESSENCHRISTOPHE VAESSEN , BERNARD MALAVAUDBERNARD MALAVAUD , JEAN-PIERRE SARRAMONJEAN-PIERRE SARRAMON , and PASCAL RISCHMANNPASCAL RISCHMANN View All Author Informationhttps://doi.org/10.1097/01.ju.0000115881.28311.f8AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "OBTURATOR INFECTED HEMATOMA AND URETHRAL EROSION FOLLOWING TRANSOBTURATOR TAPE IMPLANTATION." The Journal of Urology, 171(4), p. 1629 References 1 : La bandelette trans-obturatrice: un procédé mini-invasif pour traiter l'incontinence urinaire d'effort de la femme. Prog Urol2001; 11: 1306. Google Scholar 2 : Infected hematoma following tension-free vaginal tape implantation. J Urol2002; 168: 2549. Link, Google Scholar 3 : Urethral erosion of tension-free vaginal tape. J Urol2002; 167: 250. Abstract, Google Scholar From the Service d’Urologie, Andrologie et Transplantation Rénale, CHU Rangueil, Toulouse, France© 2004 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byDOMINGO S, ALAMÁ P, RUIZ N, PERALES A and PELLICER A (2018) DIAGNOSIS, MANAGEMENT AND PROGNOSIS OF VAGINAL EROSION AFTER TRANSOBTURATOR SUBURETHRAL TAPE PROCEDURE USING A NONWOVEN THERMALLY BONDED POLYPROPYLENE MESHJournal of Urology, VOL. 173, NO. 5, (1627-1630), Online publication date: 1-May-2005.BONNET P, WALTREGNY D, REUL O and de LEVAL J (2018) TRANSOBTURATOR VAGINAL TAPE INSIDE OUT FOR THE SURGICAL TREATMENT OF FEMALE STRESS URINARY INCONTINENCE: ANATOMICAL CONSIDERATIONSJournal of Urology, VOL. 173, NO. 4, (1223-1228), Online publication date: 1-Apr-2005. Volume 171Issue 4April 2004Page: 1629 Advertisement Copyright & Permissions© 2004 by American Urological Association, Inc.Keywordspostoperative complicationsurethra pathologyinfectionprosthesis implantationMetricsAuthor Information XAVIER GAME More articles by this author MARC MOUZIN More articles by this author CHRISTOPHE VAESSEN More articles by this author BERNARD MALAVAUD More articles by this author JEAN-PIERRE SARRAMON More articles by this author PASCAL RISCHMANN More articles by this author Expand All Advertisement PDF downloadLoading ...
FACTORS FOR GLAUCOMA PROGRESSION AND THE EFFECT OF TREATMENT (2003)

Leske, M C; Heijl, A; Hussein, M; Bengtsson, B; Hyman, L; Komaroff, E for the Early Manifest Glaucoma Trial Group. Author Information
YAP is a novel regulator of CD4+ and CD8+ T cells during activation, differentiation, and anti-tumor immunity (2020)

Abstract Advanced understanding of T cell regulation has fueled cancer immunotherapy, but durable responses remain confined to a minority of patients. Poor responses can be linked to either suppressed T cell function in tumors or “cold” tumors that exclude immune cells. Identifying novel T cell regulators involved in these processes is a high priority. Our studies identified the protein YAP as a novel regulator of T cells. YAP mRNA and protein were rapidly expressed after T cell activation in mouse CD4+ and CD8+ T cells. T cell-specific Yap knockout (YapKO) generated CD4+ and CD8+ T cells that express elevated levels of activation markers (CD25, CD44, CD69) compared to WT cells. YapKO increased the sensitivity of T cells to anti-CD3 dose, and increased CD4+ T cell differentiation efficiency under Th1, Th2, Th17, and Treg skewing conditions. YapKO CD8+ T cells expanded &amp;gt;20-fold more than WT when cultured in engineered hydrogel matrices optimized for T cell expansions and adoptive transfer. Syngeneic tumors grown in T cell YapKO mice had impaired growth and increased immune infiltration compared to tumors in WT hosts. Co-adoptive transfer of YapKO and WT CD8+ T cells showed only YapKO cells infiltrated B16F10 tumors. RNAseq of CD4+ and CD8+ T cells from tumors and draining lymph nodes showed gene expression changes including upregulation of T cell receptor and cytokine signaling pathways in YapKO hosts. T cells from tumor-draining lymph nodes were not significantly different between YapKO and WT. YapKO gene signatures correlated with immune infiltration and survival in multiple human cancers in TCGA. Our data demonstrated YAP is a novel regulator of diverse T cell functions and may be a useful target for enhancing responses to cancer immunotherapy.
DOP031 A multicenter study to evaluate magnetic resonance enterography (MRE) for selection of Crohn's disease patients for inclusion into a therapeutic clinical trial (2014)

Session 4 Diagnosis: What's new?
The aryl hydrocarbon receptor repressor (2008)

The aryl hydrocarbon receptor repressor (AHRR) is a bHLH/Per-ARNT-Sim transcription factor located in a&#13;\nregion of chromosome 5 (5p15.3) that has been proposed to contain one or more tumor suppressor genes. We&#13;\nreport here consistent downregulation of AHRR mRNA in human malignant tissue from different anatomical&#13;\norigins, including colon, breast, lung, stomach, cervix, and ovary, and demonstrate DNA hypermethylation as&#13;\nthe regulatory mechanism of AHRR gene silencing. Knockdown of AHRR gene expression in a human lung cancer&#13;\ncell line using siRNA significantly enhanced in vitro anchorage-dependent and -independent cell growth as&#13;\nwell as cell growth after transplantation into immunocompromised mice. In addition, knockdown of AHRR&#13;\nin non-clonable normal human mammary epithelial cells enabled them to grow in an anchorage-independent&#13;\nmanner. Further, downregulation of AHRR expression in the human lung cancer cell line conferred resistance&#13;\nto apoptotic signals and enhanced motility and invasion in vitro and angiogenic potential in vivo. Ectopic&#13;\nexpression of AHRR in tumor cells resulted in diminished anchorage-dependent and -independent cell growth&#13;\nand reduced angiogenic potential. These results therefore demonstrate that AHRR is a putative new tumor&#13;\nsuppressor gene in multiple types of human cancers.
Performance Improvement for H.264 Video Encoding using ILP Embedded Processor (2006)

In this paper, we examine the impact of instruction level parallelism (ILP) on the full H.264 video encoding application and give quantitative performance measures of a superscalar architecture. Most research efforts have concentrated on the data intensive parts, such as kernels but these are taking less time from the entire execution as encoders are using new, more efficient algorithms. This important fact cannot be neglected since new video encoding standards have been proposed and the amount of other than data intensive computations has increased significantly. We observed significant improvement for the entire application when using superscalar architecture with out-of-order execution scheme. Tradeoffs in superscalar performance are also evaluated with combinations of measurements from simplescalar simulator
MISO Networks With Imperfect CSIT: A Topological Rate-Splitting Approach (2017)

Recently, the Degrees-of-Freedom (DoFs) region of multiple-input-single-output (MISO) networks with imperfect channel state information at the transmitter (CSIT) has attracted significant attention. An achievable scheme, known as rate-splitting (RS), integrates common-message-multicasting and private-message-unicasting. In this paper, focusing on the general K-cell MISO IC with an arbitrary CSIT quality of each interfering link, we first identify the DoF region achieved by RS. Second, we introduce a novel scheme, so called topological RS (TRS), whose novelties compared with RS lie in a multi-layer structure and in transmitting multiple common messages to be decoded by groups of users rather than all users. The design of TRS is motivated by a novel interpretation of the K-cell IC with imperfect CSIT as a weighted sum of a series of partially connected networks. We show that the DoF region achieved by TRS yields the best known result so far, and we find the maximal sum DoF via hypergraph fractional packing. Finally, for a realistic scenario where each user is connected to three dominant transmitters, we identify the sufficient condition where TRS strictly outperforms conventional schemes, and show that TRS is optimal for some CSIT qualities.
High-field transport and electroluminescence in ZnS phosphor layers (1998)

A full-band Monte Carlo simulation of the high-field electron transport in the ZnS phosphor layer of an alternating-current thin-film electroluminescent device is performed. The simulation includes a nonlocal empirical pseudopotential band structure for ZnS and the relevant scattering mechanisms for electrons in the first four conduction bands, including band-to-band impact ionization and impact excitation of Mn2+ luminescent centers. The steady-state electron energy distribution in the ZnS layer is computed for phosphor fields from 1 to 2 MV/cm. The simulation reveals a substantial fraction of electrons with energies in excess of the Mn2+ impact excitation threshold. The computed impact excitation yield for carriers transiting the phosphor layer exhibits an approximately linear increase with increasing phosphor field above threshold. The onset of Mn2+ impact excitation coincides with the onset of band-to-band impact ionization of electron-hole pairs which prevents electron runaway at high electric fields.