gebhart/patrepeval huggingface dataset:
Bit-Line Organization in Register Files for Low-Power and High-Performance Applications (2006)

As the leakage current keeps increasing in every generation of VLSI processing technology, appropriate selection of the local and global bit-line organization of Register Files (RFs) becomes an important design issue for low-power and high-performance applications. In this paper, several different bit-line organizations are proposed based on simulation results for designing low-power and high-performance RFs using 65 nm CMOS devices, while maintaining maximum robustness against noise.
Sub‐Solidus Synthesis and Microwave Dielectric Characterization of Plagioclase Feldspars (2005)

Na x Ca 1− x Al 2− x Si 2+ x O 8 plagioclase solid solutions (0≤ x ≤1) were synthesized under sub‐solidus conditions using a solid‐state reaction technique. The plagioclase formation and the sintering temperature decreased with an increase in x from the anorthite (CaAl 2 Si 2 O 8 ; x =0) to the albite (NaAlSi 3 O 8 ; x =1). Microwave (MW) dielectric measurements revealed that slow‐cooled ( P 1 ) anorthite exhibited higher Q × f values than fast‐cooled ( I 1 ) anorthite. Slow cooling also considerably improved the Q × f values of the sodium‐rich Na x Ca 1− x Al 2− x Si 2+ x O 8 solid solutions (0.8≤ x ≤1), where the highest Q × f value of 17 600 GHz was obtained for slow‐cooled Na 0.8 Ca 0.2 Al 1.2 Si 2.8 O 8 . The temperature coefficient of resonant frequency (τ f ) approached zero for 0.8≤ x ≤1.
Kinematic Comparison between Medially Congruent and Posterior-Stabilized Third-Generation TKA Designs (2021)

<b>Background</b>: This study compares knee kinematics in two groups of patients who have undergone primary total knee arthroplasty (TKA) using two different modern designs: medially congruent (MC) and posterior-stabilized (PS). The aim of the study is to demonstrate only minimal differences between the groups. <b>Methods</b>: Ten TKA patients (4 PS, 6 MC) with successful clinical outcomes were evaluated through 3D knee kinematics analysis performed using a multicamera optoelectronic system and a force platform. Extracted kinematic data included knee flexion angle at heel-strike (KFH), peak midstance knee flexion angle (MSKFA), maximum and minimum knee adduction angle (KAA), and knee rotational angle at heel-strike. Data were compared with a group of healthy controls. <b>Results:</b> There were no differences in preferred walking speed between MC and PS groups, but we found consistent differences in knee function. At heel-strike, the knee tended to be more flexed in the PS group compared to the MC group; the MSKFA tended to be higher in the PS group compared to the MC group. There was a significant fluctuation in KAA during the swing phase in the PS group compared to the MC group, PS patients showed a higher peak knee flexion moment compared to MC patients, and the PS group had significantly less peak internal rotation moments than the MC group. <b>Conclusions:</b> Modern, third-generation TKA designs failed to reproduce normal knee kinematics. MC knees tended to reproduce a more natural kinematic pattern at heel-strike and during axial rotation, while PS knees showed better kinematics during mid-flexion.
Magnetresonanz-Cholangiografie (MRCP) bei Patienten mit Ischemic-Type Biliary Lesions (ITBL): eine Fall-Kontroll-Studie (2011)

In patients with ITBL, MR cholangiography reveals characteristic features that may allow differentiation from other biliary complications after liver transplantation.
Separation of enantiomers by their enantiospecific interaction with achiral magnetic substrates (2018)

It is commonly assumed that recognition and discrimination of chirality, both in nature and in artificial systems, depend solely on spatial effects. However, recent studies have suggested that charge redistribution in chiral molecules manifests an enantiospecific preference in electron spin orientation. We therefore reasoned that the induced spin polarization may affect enantiorecognition through exchange interactions. Here we show experimentally that the interaction of chiral molecules with a perpendicularly magnetized substrate is enantiospecific. Thus, one enantiomer adsorbs preferentially when the magnetic dipole is pointing up, whereas the other adsorbs faster for the opposite alignment of the magnetization. The interaction is not controlled by the magnetic field per se, but rather by the electron spin orientations, and opens prospects for a distinct approach to enantiomeric separations.
Multiband planar metallodielectric photonic crystals using frequency selective surface techniques (2004)

Two-dimensional single layer metallodielectric photonic crystals (MDPCs) with multiple stopbands in the far-infrared transmission spectrum have been designed and fabricated using frequency selective surface (FSS) techniques at the micron-scale. These surfaces consist of self-similar fractal cross-dipole or fractal square patch metallic elements patterned on thin, flexible dielectric substrates using standard semiconductor microfabrication techniques. Optimization of design parameters, such as element spacing, through the application of a periodic method of moments (PMM) modeling code leads to experimental results with two transmission stopbands, each with greater than 10 dB attenuation. These results are in excellent agreement with those predicted by the PMM model. The positions of the bands can be readily controlled by utilizing the modeling data to determine optimum element geometries.
Rapid high-throughput cloning and stable expression of antibodies in HEK293 cells (2016)

Single-cell based amplification of immunoglobulin variable regions is a rapid and powerful technique for cloning antigen-specific monoclonal antibodies (mAbs) for purposes ranging from general laboratory reagents to therapeutic drugs. From the initial screening process involving small quantities of hundreds or thousands of mAbs through in vitro characterization and subsequent in vivo experiments requiring large quantities of only a few, having a robust system for generating mAbs from cloning through stable cell line generation is essential. A protocol was developed to decrease the time, cost, and effort required by traditional cloning and expression methods by eliminating bottlenecks in these processes. Removing the clonal selection steps from the cloning process using a highly efficient ligation-independent protocol and from the stable cell line process by utilizing bicistronic plasmids to generate stable semi-clonal cell pools facilitated an increased throughput of the entire process from plasmid assembly through transient transfections and selection of stable semi-clonal cell pools. Furthermore, the time required by a single individual to clone, express, and select stable cell pools in a high-throughput format was reduced from 4 to 6months to only 4 to 6weeks.
Reversible Redox-Responsive Assembly/Disassembly of Nanoparticles Mediated by Metal Complex Formation (2014)

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTReversible Redox-Responsive Assembly/Disassembly of Nanoparticles Mediated by Metal Complex FormationMarkus B. Bannwarth*†‡, Thomas Weidner†, Evelyn Eidmann†, Katharina Landfester†, and Daniel Crespy*†View Author Information† Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany‡ Graduate School Materials Science in Mainz, Staudinger Weg 9, 55128 Mainz, Germany*E-mail: [email protected]*E-mail: [email protected]Cite this: Chem. Mater. 2014, 26, 3, 1300–1302Publication Date (Web):January 21, 2014Publication History Received12 December 2013Revised14 January 2014Published online24 January 2014Published inissue 11 February 2014https://pubs.acs.org/doi/10.1021/cm4040769https://doi.org/10.1021/cm4040769rapid-communicationACS PublicationsCopyright © 2014 American Chemical SocietyRequest reuse permissionsArticle Views1807Altmetric-Citations21LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Bacteria,Ions,Nanoparticle formation,Nanoparticles,Organic compounds Get e-Alerts
Composting of Yard Waste and Wastewater Treatment Plant Sludge Mixtures (1993)

Composting of yard waste and sludge/yard waste mixtures was investigated during laboratory and field testing. A strong correlation between moisture content and windrow peak temperatures was observed. Odors were detected at cocomposting windrows when temperatures exceeded 54°C. The sludge to yard waste mixture ratio was found to affect resulting compost particle size and, consequently, oxygen transport. Compost quality was excellent, with pesticides below detection level and low concentrations of heavy metals.
MMP13 mutation causes spondyloepimetaphyseal dysplasia, Missouri type (SEMDMO) (2005)

MMPs, which degrade components of the ECM, have roles in embryonic development, tissue repair, cancer, arthritis, and cardiovascular disease. We show that a missense mutation of MMP13 causes the Missouri type of human spondyloepimetaphyseal dysplasia (SEMD(MO)), an autosomal dominant disorder characterized by defective growth and modeling of vertebrae and long bones. Genome-wide linkage analysis mapped SEMD(MO) to a 17-cM region on chromosome 11q14.3-23.2 that contains a cluster of 9 MMP genes. Among these, MMP13 represented the best candidate for SEMD(MO), since it preferentially degrades collagen type II, abnormalities of which cause skeletal dysplasias that include Strudwick type SEMD. DNA sequence analysis revealed a missense mutation, F56S, that substituted an evolutionarily conserved phenylalanine residue for a serine in the proregion domain of MMP13. We predicted, by modeling MMP13 structure, that this F56S mutation would result in a hydrophobic cavity with misfolding, autoactivation, and degradation of mutant protein intracellularly. Expression of wild-type and mutant MMP13s in human embryonic kidney cells confirmed abnormal intracellular autoactivation and autodegradation of F56S MMP13 such that only enzymatically inactive, small fragments were secreted. Thus, the F56S mutation results in deficiency of MMP13, which leads to the human skeletal developmental anomaly of SEMD(MO).
An exploratory study on the use of camera phones and pico projectors in rural India (2011)

We explore the potential of using camera phones and pico projectors in rapid creation and presentation of digital content in a development context. A camera phone based content authoring application was designed and deployed with three different user populations in the domains of classroom education and health care. Our findings show that despite the variations in education levels, cultural background, and technology exposure, users successfully created and presented different forms of digital content using the camera phone and pico projector.
Orientations of side chains and adsorbed liquid crystal molecules on a rubbed polyimide surface studied by optical second harmonic generation (2001)

Surface second harmonic generation was used to obtain approximate orientational distributions of the side chains and the adsorbed liquid crystal (LC) molecules on a rubbed side-chain polyimide surface. Both the side chains and the LC molecules appear to be well aligned in the rubbing direction but tilted away from the surface in the antirubbing direction. The latter yields a negative pretilt angle in a homogeneously aligned LC film sandwiched between two such surfaces. The side chains and the LC molecules, however, have antiparallel orientations at the surface.
Hydrothermal Method Preparation of Flower-Like Ce-Doped ZnO as an Efficient Photocatalyst (2018)

Well-crystalline flower-like Ce-doped ZnO were synthesized by facile and low-cost hydrothermal method. The prepared samples were characterized by a variety of characterization techniques such as X-ray diffraction (XRD), Fourier Transform Infrared Spectrometer (FT-IR), UV-visible spectroscopy, scanning electron microscopy (SEM) combined with energy dispersive X-ray diffraction (EDX), to study the crystal structure, optical properties, surface morphology and chemical composition. It was observed from XRD and FT-IR results that synthesized powder had hexagonal wurtzite structure. The photocatalytic activities of the prepared samples were evaluated by photocatalytic degradation of methyl orange (MO) and Rhodamine B (RhB) under UV light irradiation. The results showed that the Ce-doped ZnO photocatalyst with 0.5% cerium exhibited highest photocatalytic activity compared to other samples. The enhanced photocatalytic activity could be attributed to inhibition of the electron-hole pair’s recombination.
Glial Cells Drive Preconditioning-Induced Blood-Brain Barrier Protection (2011)

Our data show that the blood-brain barrier can be directly preconditioned and that astrocytes are major mediators of IPC protection.
Use of a Digoxigenin-Labeled RNA Probe to Detect All 24 Serotypes of Bluetongue Virus in Cell Culture (1993)

A digoxigenin-labeled RNA probe, corresponding to the section of the bluetongue virus (BTV) serotype 17 genome coding for nonstructural protein-1 (NS1), was applied to noninfected cell cultures and cell cultures infected with 24 different serotypes of BTV, 2 serotypes of epizootic hemorrhagic disease virus, and African horse sickness virus type 4. The probe hybridized to all cell cultures infected with the various BTV serotypes but did not hybridize to noninfected cell cultures or cell cultures infected with any of the other orbiviruses.
<title>Quantification of coronary arterial plaque volume using 3D reconstructions formed by fusing intravascular ultrasound and biplane angiography</title> (1999)

This paper, through plaque quantification, demonstrates the use of three-dimensional (3D) reconstructions of coronary arteries to assess compensatory enlargement. The lumen and medial-adventitial border are segmented from intravascular ultrasound (IVUS) images using a novel 3D method called active surfaces and the segmented data is used to calculate the cross-sectional area of the lumen and vessel, respectively. The area of plaque for each slice is the difference of the two. Information about the distance between path points, located using a calibrated biplane angiography system, is used for the calculation of plaque volume. This quantification system can be used to track the progression or regression of atherosclerosis and is currently being used to document compensatory enlargement, a physiological phenomenon in which the overall vessel cross-sectional area increases with an increase in plaque area with little or no decrease in luminal cross-sectional area. Four ex-vivo cases have been quantified, all demonstrating this remodeling mechanism, shown by strong positive correlation between plaque area and vessel area over the reconstructed length of the vessel (R equals 0.98, R equals 0.93, R equals 0.98, R equals 0.68).
Spatio-temporal coupled Bayesian Robust Principal Component Analysis for road traffic event detection (2013)

Road traffic sensors provide us with rich multi-variable datastreams about the current traffic conditions. Occasionally, there are unusual traffic events (such as accidents, jams, severe weather, etc) that disrupt the expected road traffic conditions. Detecting the occurrence of such events in an online and real-time manner is useful to drivers in planning their routes and in the management of the transportation infrastructure. We propose a new method for detecting traffic events that impact road traffic conditions by extending the Bayesian Robust Principal Component Analysis (RPCA) approach. Our method couples multiple traffic datastreams so that they share a certain sparse structure. This sparse structure is used to localize traffic events in space and time. The traffic datastreams are measurements of different physical quantities (e.g. traffic flow, road occupancy) by different nearby sensors. Our proposed method process datastreams in an incremental way with little computational cost, and hence it is suitable to detect events in an online and real-time manner. We experimentally analyze the detection performance of the proposed coupled Bayesian RPCA using real data from loop detectors on the Minnesota I-494. We find that our method significantly improves the detection accuracy when compared with the traditional PCA and non-coupled Bayesian RPCA.
ChemInform Abstract: Bioisosterism: A Rational Approach in Drug Design (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Chalcone skeleton promotes transcription of gp91‐phox gene but inhibits expression of gp91‐phox protein, and hydroxyl groups in hydroxychalcones participate in the stable expression of gp91‐phox protein (2019)

The effects of chalcone and butein on the induction of the superoxide anion (O<sub>2</sub> <sup>-</sup> )-generating system were studied in U937 cells by all-trans retinoic acid (RA). The chalcone skeleton, a common structural motif in them, significantly enhanced the transcription of gp91-phox in an epigenetic manner. In contrast, chalcone and butein showed opposite effects on the induction of the O<sub>2</sub> <sup>-</sup> -generating activity by RA and the expression of gp91-phox protein. Chalcone inhibited, whereas butein promoted, the induction of O<sub>2</sub> <sup>-</sup> -generating activity by RA and the expression of gp91-phox protein. These data raise the possibility that modification of the chalcone skeleton could produce more effective differentiation-promoting agents.
Effect of Postoperative Mechanical Axis Alignment on Survival and Functional Outcomes of Modern Total Knee Arthroplasties with Cement (2018)

Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Complete Genome Sequence of Mycobacterium avium subsp. hominissuis Strain H87 Isolated from an Indoor Water Sample (2017)

<i>Mycobacterium avium</i> subsp. <i>hominissuis</i> is an environmentally acquired bacterium known to cause pulmonary and soft tissue infections, lymphadenitis, and disseminated disease in humans. We report here the complete genome sequence of strain H87, isolated from an indoor water sample, as a single circular chromosome of 5,626,623 bp with a G+C content of 68.8%.
A compact echelle spectrograph for characterization of astro-combs (2017)

We present an echelle spectrograph that is optimized for characterization of frequency combs for astronomical applications (astro-combs). In spite of its very compact and cost-efficient design, it allows viewing the spectrum of a frequency comb in nearly the same way as a full-sized high-resolution echelle spectrograph as used at astronomical observatories. This is of great value for testing and characterizing astro-combs during their assembly phase. The spectrograph can further be utilized to effectfully demonstrate the remarkable capabilities of astro-combs.
Mechanical properties of nanocomposite systems (2007)

The interaction zone and the bridge formation hypotheses are often used to explain the changes in mechanical properties and glass transition temperature that accompany by the addition of nanoparticles to a polymer matrix. We employ a formalism that relies on local stress fluctuations to calculate the local mechanical properties of nanocomposites in order to examine the validity of these theories. Advanced Monte Carlo techniques involving chain connectivity algorithms are used to create statistically independent configurations and aid in the efficient sampling of the stress. Three types of polymer particle interaction are considered. An increase of the mechanical properties is found for attractive and neutral particles, while for repulsive ones a decrease is observed. For the attractive case, the formation of a stiff glassy layer is apparent in the vicinity of the nanoparticle. The distribution of local moduli for the nanocomposite is narrower than that of the unfilled polymer, suggesting that nanoparticles reinforce glassy polymers by reducing the degree of mechanical inhomogeneity. Results are presented for the effect of particle size, polymer chain length, volume fraction and surface area of the particles on mechanical properties. Oscillatory deformations are also considered in order to address the effects of frequency on the mechanical properties of nanocomposites.
Self-aligned vertical electrostatic combdrives for micromirror actuation (2003)

We analyze the effect of misalignment in electrostatic combdrives, and describe a fabrication technology that minimizes misalignment in vertical electrostatic combdrives by creating self-aligned, vertically staggered electrodes. Self-alignment of the interdigitated electrodes simplifies fabrication and minimizes failures due to electrostatic instability, thus enabling fabrication of narrow-gap, high-force actuators with high yield. The process is based on deep-reactive ion etching (DRIE) of buried-patterned silicon-on-insulator (SOI) wafers. Measurements on fabricated combdrives show relative misalignment of less than 0.05 μm. This corresponds to less than 0.1% misalignment, which, according to our analysis, results in a travel range of 98% of that for perfectly aligned drives. The validity of the process is demonstrated by fabrication of scanning micromirrors measuring 300 μm by 100 μm. Optical angular deflections from 4° at low frequency to 40° at resonance were measured for an applied voltage of 75 Vpp. Resonant frequencies ranged from 5 kHz to 15 kHz for these devices, making them suitable for high-speed, high-resolution optical scanning and switching.
Mast Cell-Lineage Versus Basophil Lineage Involvement in Myeloproliferative and Myelodysplastic Syndromes: Diagnostic Role of Cell-Immunopheno typing (1996)

Mast cells and blood basophils are distinct hemopoietic cells. They can be distinguished from each other and from all other lymphohemopoietic cells using antibodies against surface receptors or stored cytoplasmic molecules. In patients with myelodysplastic syndromes (MDS) or myeloproliferative syndromes (MPS), an elevation of metachromatically granulated cells (MCS) is frequently seen. These cells can be classified as basophils or mast cells using monoclonal antibodies (mAbs) against leukocyte antigens, including mast cell tryptase, c-kit (= mast cell growth factor [MGF] receptor), interleukin-3 receptor alpha chain (IL-3R alpha = CD123), and CD11b (C3biR). In a stable phase of MDS or MPS, the circulating MCS usually are basophils (histamine+, tryptase-, c-kit-, IL-3R alpha +, CD11b+). In an accelerated or terminal phase of disease, however, mast cell lineage involvement and circulating mast cell precursors (histamine+, tryptase+, c-kit+, IL-3R alpha-, CD11b-) are found in a subset of patients. The use of mAbs against mast cell antigens and granulocyte antigens is diagnostic in these patients.