gebhart/patrepeval huggingface dataset:
AdaFuse: Adaptive Temporal Fusion Network for Efficient Action Recognition (2021)

Temporal modelling is the key for efficient video action recognition. While understanding temporal information can improve recognition accuracy for dynamic actions, removing temporal redundancy and reusing past features can significantly save computation leading to efficient action recognition. In this paper, we introduce an adaptive temporal fusion network, called AdaFuse, that dynamically fuses channels from current and past feature maps for strong temporal modelling. Specifically, the necessary information from the historical convolution feature maps is fused with current pruned feature maps with the goal of improving both recognition accuracy and efficiency. In addition, we use a skipping operation to further reduce the computation cost of action recognition. Extensive experiments on Something V1 &amp; V2, Jester and Mini-Kinetics show that our approach can achieve about 40% computation savings with comparable accuracy to state-of-the-art methods. The project page can be found at https://mengyuest.github.io/AdaFuse/
Abstract 16486: Non-Contrast T1-Mapping is a Novel Diagnostic Tool for Acute Myocarditis on Cardiovascular Magnetic Resonance Imaging (2011)

Background: The accurate diagnosis of acute myocarditis on cardiovascular magnetic resonance imaging (CMR) often requires multiple modalities, including T2-weighted (T2w), early and late gadolinium...
Automatic ML-based vestibular gait classification: examining the effects of IMU placement and gait task selection (2022)

These findings highlighted differences in upper extremity kinematics during walking with eyes closed that were characteristic of vestibular deficits and showed evidence of the discriminative ability of IMU-based automated screening for vestibular deficits. Further research should explore the mechanisms driving arm swing differences in the vestibular population.
Ferromagnetism in thin-film Cr-doped topological insulator Bi₂Se₃ (2012)

We report on the observation of ferromagnetism in epitaxial thin films of the topological insulator compound Bi2Se3 with chromium doping. The structural, magnetic, and magnetoelectrical properties of Bi2Se3 were investigated for Cr concentrations up to 10%. For a Cr content up to similar to 5% the films are of good crystalline quality, with the lattice parameter a decreasing and the lattice parameter c increasing with increasing Cr concentration. The Curie temperature reached a maximum T-C=20K for 5.2% Cr. Well-defined ferromagnetic hysteresis in the magnetization and in the magnetoresistance was also observed in these films. (C) 2012 American Institute of Physics. [doi:10.1063/1.3688043]
New blue phosphorescent heteroleptic Ir(iii) complexes with imidazole- and N-methylimidazole carboxylates as ancillary ligands (2020)

The organic light-emitting diodes fabricated using <bold>Ir3</bold> and <bold>Ir4</bold> as dopant materials in the emissive layers were found to emit blue emission with peaks at 469 and 471 nm and maximum external quantum efficiencies of 20.0 and 22.4%, respectively.
Synthesis of 1‐Octanol and 1,1‐Dioctyl Ether from Biomass‐Derived Platform Chemicals (2012)

The happy medium: A new catalytic pathway for the synthesis of the linear primary C(8) alcohol products 1-octanol and dioctyl ether from furfural and acetone has been developed using retrosynthetic analysis. This opens a general strategy for the synthesis of medium-chain-length alcohols from carbohydrate feedstock.
Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor BI-4924 Disrupts Serine Biosynthesis (2019)

Phosphoglycerate dehydrogenase (PHGDH) is known to be the rate-limiting enzyme in the serine synthesis pathway in humans. It converts glycolysis-derived 3-phosphoglycerate to 3-phosphopyruvate in a co-factor-dependent oxidation reaction. Herein, we report the discovery of <b>BI-4916</b>, a prodrug of the co-factor nicotinamide adenine dinucleotide (NADH/NAD<sup>+</sup>)-competitive PHGDH inhibitor <b>BI-4924</b>, which has shown high selectivity against the majority of other dehydrogenase targets. Starting with a fragment-based screening, a subsequent hit optimization using structure-based drug design was conducted to deliver a single-digit nanomolar lead series and to improve potency by 6 orders of magnitude. To this end, an intracellular ester cleavage mechanism of the ester prodrug was utilized to achieve intracellular enrichment of the actual carboxylic acid based drug and thus overcome high cytosolic levels of the competitive cofactors NADH/NAD<sup>+</sup>.
A novel vitronectin-binding protein of Pseudomonas aeruginosa for effective infection of the airways (2015)

Objectives Pseudomonas aeruginosa is a Gram-negative species that causes chronic and acute infections of the lung, skin, urinary tract and eyes. Most P. aeruginosa isolates are highly resistant to antibiotics and difficult to eradicate due to biofilm formation. The bacterium is known to utilize host proteins by diverse strategies in order to enhance its virulence. Vitronectin is a glycoprotein that is abundant in serum and the extracellular matrix, and is involved in cell adhesion, migration, tissue repair and regulation of the complement cascade. The concentration of vitronectin in the lung reflects the level of inflammation in patients with interstitial lung disease. Furthermore, the production is upregulated in patients with cystic fibrosis, which are often chronically colonised with P. aeruginosa. In this study, we analysed the vitronectin-binding capability of clinical strains and identified the P. aeruginosa surface proteins involved in vitronectin binding. Methods P. aeruginosa clinical isolates (n=64) from the airway (n=36), blood (n=15) and urine (n=13), in addition to the reference strain (PAO1) were analysed in a direct binding assay using [125I]-vitronectin. To identify the vitronectin-binding surface proteins of P. aeruginosa, the outer membrane proteins of PAO1 were separated by 2D-SDS-PAGE and western blotting. Vitronectin binding proteins of P. aeruginosa were recombinantly expressed in Escherichia coli and protein-protein interactions were evaluated by ELISA and flow cytometry. P. aeruginosa transposon mutants obtained from the “P. aeruginosa two-allele library” were analysed for vitronectin binding by [125I]-vitronectin or vitronectin coated to a glass surface. Results Our direct binding assay revealed that P. aeruginosa airway isolates bound significantly more vitronectin in comparison to blood (p=0.02) and urine isolates (p=0.04) (Fig. A). Using an approach consisting of 2D-SDS-PAGE and western blotting, we identified two outer membrane proteins that interacted with vitronectin (Fig. B). Expression of one of those (vitronectin binding protein 1; VnBp1) in an E. coli laboratory strain resulted in VnBp1 on the cell surface, and a vitronectin-binding phenotype. In addition, recombinantly expressed and purified VnBP1 showed a dose-dependent interaction with vitronectin in an ELISA (Fig. C). P. aeruginosa with a transposon insert in the vnBp1 gene bound significantly less vitronectin in comparison to the wild type (p=0.0009). Moreover, vnBp1 deficient mutants also showed significant reduced adherence to vitronectin coated glass slide (p≤0.001) in comparison to the wild type (Fig. D). Conclusions P. aeruginosa isolates cultured from the lung bind significantly more vitronectin in comparison to strains cultured from urine or blood. Vitronectin is recruited at the surface via VnBp1. This mechanism is likely to be of great importance for P. aeruginosa adhesion to the airway epithelial and basal lamina of disrupted airway epithelial cell layer and hence for the colonisation of the respiratory tract.
Cardiac Arrythmias: Multimodal Assessment Integrating Body Surface ECG Mapping into Cardiac Imaging (2013)

By combining information on anatomy, substrate, and electrical activation, the fusion of BSM and imaging enables comprehensive noninvasive assessment of cardiac arrhythmias, with potential applications for diagnosis, prognosis, and ablation targeting. Online supplemental material is available for this article.
Quantum Logic Locking for Security (2023)

Having access to a unique quantum circuit that one wants to protect against use by others is a very likely scenario in industrial computing. However, currently, users rely on classical computer security schemes, which have known shortcomings. In this paper, we introduce a novel protection scheme along with a survey of other known methods to protect quantum information. In particular, we review physically unclonable functions (PUFs), obfuscation, and introduce quantum logic locking (QLL). The latter technique provisions end users to protect their circuit from an adversary through the use of a secret key.
Translational Stroke Research (2017)

Stroke risk and poststroke disability have steadily decreased in the United States over the past 2 decades because of improved prevention and access to reperfusion therapies for acute ischemic stroke, such as tPA (tissue-type plasminogen activator; alteplase) and endovascular thrombectomy. Despite the efficacy and safety of thrombolysis and thrombectomy, not all patients who receive the treatment improve to full, independent recovery, and most patients are ineligible for treatment. Additionally, there are no efficacious treatments to improve long-term outcomes for patients after the acute phase of ischemic stroke or to reduce brain injury induced by acute intracerebral hemorrhage. Therefore, development of new therapies for both acute and chronic stroke is sorely needed.
Metal-metal bonds involving actinides. Functionalization of activated carbon-hydrogen bonds and unusual oligomerization chemistry mediated by a thorium-ruthenium complex (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMetal-metal bonds involving actinides. Functionalization of activated carbon-hydrogen bonds and unusual oligomerization chemistry mediated by a thorium-ruthenium complexRichard S. Sternal, Michal Sabat, and Tobin J. MarksCite this: J. Am. Chem. Soc. 1987, 109, 25, 7920–7921Publication Date (Print):December 1, 1987Publication History Published online1 May 2002Published inissue 1 December 1987https://pubs.acs.org/doi/10.1021/ja00259a072https://doi.org/10.1021/ja00259a072research-articleACS PublicationsRequest reuse permissionsArticle Views256Altmetric-Citations44LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Constraint-based random stimuli generation for hardware verification (2006)

We report on random stimuli generation for hardware verification in IBM as a major application of various artificial intelligence technologies, including knowledge representation, expert systems, and constraint satisfaction. The application has been developed for almost a decade, with huge payoffs. Research and development around this application is still thriving, as we continue to cope with the ever-increasing complexity of modern hardware systems and demanding business environments.
The potential of antibody-mediated immunity in the defence against biological weapons (2005)

Antibody-mediated immunity (AMI) has been used for the treatment and prevention of infectious diseases for > 100 years, and has a remarkable record of safety, efficacy and versatility. AMI can be used for defence against a wide variety of biological weapons, and passive antibody (Ab) therapy has the potential to provide immediate immunity to susceptible individuals. Recent advances in the Ab field make it possible to generate Abs with enhanced antimicrobial functions. There are significant gaps in our understanding of Ab function, such that the development of Ab-based strategies remains a largely empirical exercise. Nevertheless, the advantages inherent in the therapeutic and prophylactic use of AMI provide a powerful rationale for continued development that will undoubtedly yield many new vaccines and therapeutic Abs.
Texture and surface morphology evolution of Ag(Cu) layers on indium tin oxide thin films (2008)

The evolution of surface morphology and (1 1 1) texture of Ag metallization on indium tin oxide (ITO) were improved by Cu additions to the Ag layer. X-ray diffraction (XRD) and atomic force microscopy (AFM) were used to characterize the surface morphology and the texture evolution of Ag(Cu). These results were compared with those obtained from pure Ag on ITO. After thermal annealing, AFM and XRD data show different modes of surface morphology evolution and crystallographic texture evolution with thermal annealing temperature. Differences in surface and texture between Ag(Cu) and Ag films were explained in terms of surface energy and grain boundary grooving as a function of annealing temperatures. The addition of Cu atoms into the silver thin films influenced the grain growth by modification of surface energy and/or adatom mobility. Rutherford backscattering spectrometry (RBS) and electrical resistivity measurements showed good thermal stability of Ag(Cu) in vacuum at temperatures varying from 300 to 600 °C for 1 h. AFM, RBS and electrical resistivity data also confirmed the absence of agglomeration occurrence during the annealing process. The enhanced texture and thermal stability indicated that Ag(Cu) alloy films constitute potential contact materials for MOSFET for better electromigration resistance and for optical devices such as flip-chip light-emitting diodes.
<title>Oxide-confined vertical-cavity surface-emitting lasers, quantum dots, and the Purcell effect: can scaling the mode size improve laser performance?</title> (1999)

The developing of vertical-cavity surface-emitting lasers (VCSELs) has led to new types of low power, high efficiency light sources for data communication. The small size, low power, and surface-normal emission of VCSELs has enabled relatively dense 2D arrays for highly parallel data communication and optical signal processing. In this paper we examine the issues of device scaling on VCSEL performance. We look specifically at what benefits may be derived from continued scaling of the active volume down to minimum sized dimensions, and what device schemes may be required to obtain the scaling. Laser rate equations are used to show that when the VCSEL mode volume is reduced to wavelength cubed dimensions, a significant improvement in modulation speed is predicted based on the radiative lifetime change due to the Purcell effect. However, several parasitic effects must be controlled in order to realize these benefits. Most important are control of the otpical loss due to diffraction or scattering, and control of the electronic losses due to carrier diffusion and surface effects. Novel optical confinement schemes based on oxide- apertures, photonic band gaps, and/or closely coupled 2D arrays may be useful for controlling optical loss, while self-assembled quantum dots are attractive for controlling electronic diffusion to dimensions within the minimum optical mode volume.
Highly Stable and Sensitive Nucleic Acid Amplification and Cell-Phone-Based Readout (2017)

Key challenges with point-of-care (POC) nucleic acid tests include achieving a low-cost, portable form factor, and stable readout, while also retaining the same robust standards of benchtop lab-based tests. We addressed two crucial aspects of this problem, identifying a chemical additive, hydroxynaphthol blue, that both stabilizes and significantly enhances intercalator-based fluorescence readout of nucleic acid concentration, and developing a cost-effective fiber-optic bundle-based fluorescence microplate reader integrated onto a mobile phone. Using loop-mediated isothermal amplification on lambda DNA we achieve a 69-fold increase in signal above background, 20-fold higher than the gold standard, yielding an overall limit of detection of 25 copies/μL within an hour using our mobile-phone-based platform. Critical for a point-of-care system, we achieve a >60% increase in fluorescence stability as a function of temperature and time, obviating the need for manual baseline correction or secondary calibration dyes. This field-portable and cost-effective mobile-phone-based nucleic acid amplification and readout platform is broadly applicable to other real-time nucleic acid amplification tests by similarly modulating intercalating dye performance and is compatible with any fluorescence-based assay that can be run in a 96-well microplate format, making it especially valuable for POC and resource-limited settings.
<title>Aluminum alloy clad fiber optic corrosion sensor</title> (1997)

Life extension programs for military metallic aircraft are becoming increasingly important as defense budgets shrink and world economies realign themselves to an uncertain future. For existing military weapon systems, metallic corrosion damage costs as estimated $DOL8 billion per year. One approach to reducing this cost is to develop a reliable method to detect and monitor corrosion in hidden metallic structure with the use of corrosion sensors which would give an early indication of corrosion without significant disassembly, thereby reducing maintenance costs. This presentation describes the development, analysis, and testing of a fiber optic corrosion sensor developed jointly with the Virginia Polytechnic Fiber and Electro-Optics Research Center and sponsored by Wright Laboratory Materials Directorate. In the sensor which was researched, the normal cladding is removed in the sensor region, and replaced with aluminum alloy and allowed to corrode on coupons representative of C/KC-135 body structure in an ASTM B117 salt spray chamber and a Boeing developed Crevice Corrosion Cell. In this approach, the optical signal output of the sensor was originally designed to increase as corrosion takes place, however interaction with the corrosion byproducts yielded different results than anticipated. These test results to determine a correlation between the sensor output and the structural degradation due to corrosion are discussed.
Efficient room temperature hydrogen sensor based on UV-activated ZnO nano-network (2017)

Room temperature hydrogen sensors were fabricated from Au embedded ZnO nano-networks using a 30 mW GaN ultraviolet LED. The Au-decorated ZnO nano-networks were deposited on a SiO<sub>2</sub>/Si substrate by a chemical vapour deposition process. X-ray diffraction (XRD) spectrum analysis revealed a hexagonal wurtzite structure of ZnO and presence of Au. The ZnO nanoparticles were interconnected, forming nano-network structures. Au nanoparticles were uniformly distributed on ZnO surfaces, as confirmed by FESEM imaging. Interdigitated electrodes (IDEs) were fabricated on the ZnO nano-networks using optical lithography. Sensor performances were measured with and without UV illumination, at room temperate, with concentrations of hydrogen varying from 5 ppm to 1%. The sensor response was found to be ∼21.5% under UV illumination and 0% without UV at room temperature for low hydrogen concentration of 5 ppm. The UV-photoactivated mode enhanced the adsorption of photo-induced O<sup>-</sup> and O<sup>2-</sup> ions, and the d-band electron transition from the Au nanoparticles to ZnO-which increased the chemisorbed reaction between hydrogen and oxygen. The sensor response was also measured at 150 °C (without UV illumination) and found to be ∼18% at 5 ppm. Energy efficient low cost hydrogen sensors can be designed and fabricated with the combination of GaN UV LEDs and ZnO nanostructures.
Hunt for new phenomena using large jet multiplicities and missing transverse momentum with ATLAS in 4.7 fb−1 of $ \sqrt {s} = 7\;TeV $ proton-proton collisions (2012)

A bstract Results are presented of a search for new particles decaying to large numbers of jets in association with missing transverse momentum, using 4.7 fb −1 of pp collision data at $ \sqrt {s} = 7\;TeV $ collected by the ATLAS experiment at the Large Hadron Collider in 2011. The event selection requires missing transverse momentum, no isolated electrons or muons, and from ≥6 to ≥9 jets. No evidence is found for physics beyond the Standard Model. The results are interpreted in the context of a MSUGRA/CMSSM supersymmetric model, where, for large universal scalar mass m 0 , gluino masses smaller than 840 GeV are excluded at the 95% confidence level, extending previously published limits. Within a simplified model containing only a gluino octet and a neutralino, gluino masses smaller than 870 GeV are similarly excluded for neutralino masses below 100 GeV.
Comparative Study of Ion Desorption from Clean and Contaminated TiO<sub>2</sub>(110) Surfaces by Slow Positron Impacts (2015)

We have compared positron-annihilation-induced ion desorption from clean and contaminated TiO2 surfaces. While O+ ions from the clean surface were detected, H+ ion desorption was observed for the contaminated surface. These results indicate that positron-stimulated desorption is sensitive to changes in the surface environment. [DOI: 10.1380/ejssnt.2015.261]
A comparison of desiccation-related proteins (dehydrin and QP47) in peas (Pisum sativum) (1995)

Abstract Dehydrin and QP47, proteins present in mature pea seeds ( Pisum sativum ), have been proposed to play protective roles during desiccation. To identify possible relationships between these proteins and desiccation tolerance, their tissue locations and patterns of synthesis and degradation have been examined during germination. Tissue locations were determined by immunocytochemistry using polyclonal antibodies raised against a conserved dehydrin amino acid sequence and against purified QP47. In embryonic axis and cotyledon cells, QP47 and dehydrin were distributed uniformly with no apparent nuclear or organellar specificity. Both proteins were present in 24 h-imbibed axes that had not initiated radicle growth but were completely absent from 24 h-imbibed axes that had begun to grow. The amounts of QP47 and dehydrin in embryonic axes decreased with time after the start of imbibition and were undetectable by 48 h. When germination was prevented by polyethylene glycol (PEG) or abscisic acid (ABA), both proteins remained at their original amounts. Thus, both QP47 and dehydrin disappeared coincidently with the beginning of growth and not simply as a function of the time after imbibition. QP47 persisted in cotyledons until at least 31 days into seedling growth, whereas dehydrin was not detectable in cotyledons after 7 days. Dehydrin, but not QP47, could be re-induced in pea shoots and cotyledons by dehydration. The timing of degradation of both proteins was correlated with the loss of desiccation tolerance during germination of pea axes.