gebhart/patrepeval huggingface dataset:
Lymphoma: monitoring tumor size and signal intensity with MR imaging. (1993)

To assess the potential value of magnetic resonance (MR) imaging in monitoring disease status, 34 patients with residual masses underwent MR imaging at sequential intervals. Patterns of signal intensity suggestive of active and inactive residual disease were compared to changes in tumor size. The signal intensity pattern was suggestive of persistent disease in 18 patients, even though tumor size was stable or decreased. Three of these patterns, seen within 6 months of initiation of therapy, were due to necrosis or inflammation. The MR imaging assessment of inactive disease was confirmed in 15 of the remaining 16 patients. In no case was an increase in tumor size seen in conjunction with a decrease in signal intensity. Because tumor size and signal intensity changes are not parallel in many cases, MR imaging may have a role in monitoring masses in patients with lymphoma. Signal intensity patterns, however, reflect gross histologic characteristics and cannot be considered specific, especially in the first 6 months after initiation of therapy.
Temperature-dependent charge transport in copper indium diselenide nanocrystal films (2012)

This manuscript reports the temperature dependence of majority carrier transport in p-type films of copper indium diselenide (CuInSe2) nanocrystals. Charge transport parameters, such as the carrier concentration and the electrical conductivity as well as the charge transport mechanisms have been characterized through measurements of electrical capacitance and electrical current as a function of applied voltage bias and temperature. At low temperatures, below 181 K, the temperature dependence of the conductivity is consistent with a variable range hopping mechanism for transport, while at higher temperatures, above 181 K, the transport mechanism shifts to nearest neighbor hopping. Charge transport measurements were also studied under AM1.5 illumination to show how energetic barriers for charge transport are reduced under solar cell-like operating conditions.
Isolation and Characterization of IFN-Gamma mRNA Derived from Mitogen-Induced Human Splenocytes (1982)

Human splenocytes from large cultures (5 1) were stimulated with Staphylococcus enterotoxin A (SEA). After 2.5 d of conditioning, poly A+RNA was isolated from these cultures and its in-vitro translational capacity was evaluated in a wheat germ extract. Injection of the RNA into Xenopus laevis oocytes yielded a low but reproducible amount of IFN activity, which was neutralizable only by an antiserum to gamma interferon (IFN-gamma) and not by antisera to alpha interferon (IFN-alpha) and/or beta interferon (IFN-beta). Formamide sucrose gradient centrifugation analysis indicated that the mRNA which codes for IFN-gamma sediments at around 15 S. The profile, however, suggested a size heterogeneity of IFN-specific mRNA. Electrophoresis of cDNA synthesized on these mRNA fractions indicated that the mRNA coding for gamma IFN has a length of between 900 and 1400 nucleotides.
Imaging the collapse of electron wave-functions: the relation to plasmonic losses (2019)

We show how free-electron interaction with plasmons in electron microscopes leads to electron-plasmon entanglement, connecting electron decoherence with plasmonic losses. We utilize this connection to propose a new method to probe plasmonic lifetimes.
Concentrations of metals in aquatic invertebrates from the Ozark National Scenic Riverways, Missouri (2007)

This report summarizes the findings of a study conducted as a pilot for part of a park-wide monitoring program being developed for the Ozark National Scenic Riverways (ONSR) of southeastern Missouri. The objective was to evaluate using crayfish (Orconectes spp.) and Asian clam (Corbicula fluminea) for monitoring concentrations of metals associated with lead-zinc mining. Lead-zinc mining presently (2007) occurs near the ONSR and additional mining has been proposed. Three composite samples of each type (crayfish and Asian clam), each comprising ten animals of approximately the same size, were collected during late summer and early fall of 2005 from five sites on the Current River and Jacks Fork within the ONSR and from one site on the Eleven Point River and the Big River, which are outside the ONSR. The Big River has been contaminated by mine tailings from historical leadzinc mining. Samples were analyzed by inductively coupled plasma mass spectrometry for lead, zinc, cadmium, cobalt, and nickel concentrations. All five metals were detected in all samples; concentrations were greatest in samples of both types from the Big River, and lowest in samples from sites within the ONSR. Concentrations of zinc and cadmium typically were greater in Asian clams than in crayfish, but differences were less evident for the other metals. In addition, differences among sites were small for cobalt in Asian clams and for zinc in crayfish, indicating that these metals are internally regulated to some extent. Consequently, both sample types are recommended for monitoring. Concentrations of metals in crayfish and Asian clams were consistent with those reported by other studies and programs that sampled streams in southeast Missouri.
Keyed logic BIST for Trojan detection in SoC (2014)

As demonstrated by the recent attack on Intel's Ivy Bridge processor, the traditional Logic Built-In Self-Test (LBIST) methods do not provide adequate protection of SoC against malicious modifications known as hardware Trojans. In this paper, we introduce a simple but efficient countermeasure against hardware Trojans which exploits non-zero aliasing probability of LBIST. We propose to generate LBIST test patterns based on a configurable key which is decided and programed into the circuit after the manufacturing stage. Since the key and hence expected LBIST signature are unknown at the manufacturing stage, an attack based on selecting suitable values for the Trojan which result in the same signature as a fault-free circuit signature becomes infeasible.
MIRAGE: The minimum information required for a glycomics experiment (2014)

The MIRAGE (minimum information required for a glycomics experiment) initiative was founded in Seattle, WA, in November 2011 in order to develop guidelines for reporting the qualitative and quantitative results obtained by diverse types of glycomics analyses, including the conditions and techniques that were applied to prepare the glycans for analysis and generate the primary data along with the tools and parameters that were used to process and annotate this data. These guidelines must address a broad range of issues, as glycomics data are inherently complex and are generated using diverse methods, including mass spectrometry (MS), chromatography, glycan array-binding assays, nuclear magnetic resonance (NMR) and other rapidly developing technologies. The acceptance of these guidelines by scientists conducting research on biological systems in which glycans have a significant role will facilitate the evaluation and reproduction of glycomics experiments and data that is reported in scientific journals and uploaded to glycomics databases. As a first step, MIRAGE guidelines for glycan analysis by MS have been recently published (Kolarich D, Rapp E, Struwe WB, Haslam SM, Zaia J., et al. 2013. The minimum information required for a glycomics experiment (MIRAGE) project - Improving the standards for reporting mass spectrometry-based glycoanalytic data. Mol. Cell Proteomics. 12:991-995), allowing them to be implemented and evaluated in the context of real-world glycobiology research. In this paper, we set out the historical context, organization structure and overarching objectives of the MIRAGE initiative.
Frequency-Tunable Microstrip Antenna With Liquid Actuator Using Gradually Widened Transmission Line (2014)

This letter reports on a mechanically reconfigurable frequency-tunable microstrip antenna that uses a liquid actuator as the dielectric layer to reduce the antenna size compared to the wavelength. By using direct polymer vacuum deposition on a liquid, the dielectric liquid can be encapsulated inside the polymer to form an actuator, which can change the liquid thickness. When the actuator is situated within the antenna, its resonant frequency can be changed by changing the liquid thickness. The liquid, which has higher permittivity than air, can decrease the antenna size. The resonant frequency of the fabricated antenna can be changed from 23.53 to 23.28 GHz via 37.6 μm of deformation.
33.3: Flexible Electrofluidic Displays Using Brilliantly Colored Pigments (2010)

Abstract We have developed a novel electrofluidic technology for displays that employs brilliantly colored, well‐saturated pigments in solution, modulated by electrowetting physics. We discuss the operating principles of the display, and demonstrate progress in key areas needed for realizing products, including fabrication on flexible substrates and performance from −28 °C to 80 °C.
Supplemental Table 2 from miR-196b Is Epigenetically Silenced during the Premalignant Stage of Lung Carcinogenesis (2023)

&lt;p&gt;PCR Primer Sequences for COBRA, MSP, and ChIP Assays.&lt;/p&gt;
Dyrk1 inhibition improves Alzheimer's disease‐like pathology (2017)

There is an urgent need for the development of new therapeutic strategies for Alzheimer's disease (AD). The dual-specificity tyrosine phosphorylation-regulated kinase-1A (Dyrk1a) is a protein kinase that phosphorylates the amyloid precursor protein (APP) and tau and thus represents a link between two key proteins involved in AD pathogenesis. Furthermore, Dyrk1a is upregulated in postmortem human brains, and high levels of Dyrk1a are associated with mental retardation. Here, we sought to determine the effects of Dyrk1 inhibition on AD-like pathology developed by 3xTg-AD mice, a widely used animal model of AD. We dosed 10-month-old 3xTg-AD and nontransgenic (NonTg) mice with a Dyrk1 inhibitor (Dyrk1-inh) or vehicle for eight weeks. During the last three weeks of treatment, we tested the mice in a battery of behavioral tests. The brains were then analyzed for the pathological markers of AD. We found that chronic Dyrk1 inhibition reversed cognitive deficits in 3xTg-AD mice. These effects were associated with a reduction in amyloid-β (Aβ) and tau pathology. Mechanistically, Dyrk1 inhibition reduced APP and insoluble tau phosphorylation. The reduction in APP phosphorylation increased its turnover and decreased Aβ levels. These results suggest that targeting Dyrk1 could represent a new viable therapeutic approach for AD.
Improved antitumor effects of 3'-deamino-3'-morpholino derivatives of pirarubicin. (1990)

The preparation and antitumor effects of 3'-deamino-3'-morpholino derivatives of pirarubicin are described. Di-N-alkylation of pirarubicin with bis(2-iodoethyl)ether gave 3'-morpholino-pirarubicin, which was converted into its 13-tosylhydrazone, 13-deoxy derivative and 13-(S)- and 13-(R)-dihydro derivatives. Intraperitoneal administration to murine tumors indicated that the effective dose ranges of the compounds having sp3 carbon at C-13 position were broader than those of the compounds having sp2 carbon. By oral administration, 13-(S)-dihydro isomer was more effective than 13-(R)-dihydro isomer.
ChemInform Abstract: Aminoglycoside Antibiotics ‐ Modified, Enantiopure Sannamine‐ and Sporamine‐Type Glycosyl Acceptors. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Surface-modified, dye-sensitized niobate nanosheets enabling an efficient solar-driven Z-scheme for overall water splitting (2022)

While dye-sensitized metal oxides are good candidates as H<sub>2</sub> evolution photocatalysts for solar-driven Z-scheme water splitting, their solar-to-hydrogen (STH) energy conversion efficiencies remain low because of uncontrolled charge recombination reactions. Here, we show that modification of Ru dye-sensitized, Pt-intercalated HCa<sub>2</sub>Nb<sub>3</sub>O<sub>10</sub> nanosheets (<b>Ru</b>/Pt/HCa<sub>2</sub>Nb<sub>3</sub>O<sub>10</sub>) with both amorphous Al<sub>2</sub>O<sub>3</sub> and poly(styrenesulfonate) (PSS) improves the STH efficiency of Z-scheme overall water splitting by a factor of ~100, when the nanosheets are used in combination with a WO<sub>3</sub>-based O<sub>2</sub> evolution photocatalyst and an I<sub>3</sub><sup>-</sup>/I<sup>-</sup> redox mediator, relative to an analogous system that uses unmodified <b>Ru</b>/Pt/HCa<sub>2</sub>Nb<sub>3</sub>O<sub>10</sub>. By using the optimized photocatalyst, PSS/<b>Ru</b>/Al<sub>2</sub>O<sub>3</sub>/Pt/HCa<sub>2</sub>Nb<sub>3</sub>O<sub>10</sub>, a maximum STH of 0.12% and an apparent quantum yield of 4.1% at 420 nm were obtained, by far the highest among dye-sensitized water splitting systems and comparable to conventional semiconductor-based suspended particulate photocatalyst systems.
Malignant parotid tumors in 110 consecutive patients: Treatment results and prognosis (1992)

The UICC 1987 classification system was used to retrospectively analyze the treatment results and prognostic factors in 110 consecutive patients. All of the patients had malignant parotid tumors which had been diagnosed and treated during the period from 1970 to 1986. Treatment consisted of surgery, radiotherapy, or a combination. Malignant mixed tumors were seen in 28% of the patients, mucoepidermoid tumors in 18%, adenoid cystic tumors in 15%, acinic tumors in 13%, undifferentiated tumors in 11%, adenocarcinomas in 10%, and other types in 5%. Ten-year corrected survival rate was 52%, and significant differences of survival were found between: 1. patients with disease stages I through IV (I: 85%; II: 69%; III: 43%; IV: 14%); 2. those with local tumor extension (34%) and without local tumor extension (79%); 3. patients with facial nerve palsy (0%) and without facial nerve palsy (57%); and 4. those with low- or intermediate-grade malignant tumors (69% combined) and those with high-grade malignant tumors (30%). After primary treatment, 45% of the patients were cured, and, additionally, 22% were salvaged after local or neck node recurrences. It is concluded that there is a good correlation between TNM classification of UICC 1987 (stage and local extension of tumor) and prognosis, and that facial nerve palsy and grade of malignancy are important prognostic factors.
Effectiveness of the Chinese Herbal Formula TongXieYaoFang for Irritable Bowel Syndrome: A Systematic Review (2006)

There is evidence to indicate the potential usefulness of TXYF-A for IBS patients. The results were limited by the poor quality and heterogeneity of these studies. Further studies with carefully designed, randomized double-blinded placebo-controlled trials will be needed to confirm the effectiveness of TXYF or TXYF-A for IBS.
Workshop on data management and data deposition for biological images (2022)

Summary report about a workshop on research data management and data deposition for biological images. This workshop took place on 23/06/2022 and was organized by VIB and Flanders Bioimaging consortium in collaboration with Elixir Belgium and Flemish Supercomputer Center. https://training.vib.be/all-trainings/workshop-data-management-and-data-deposition-biological-images
Um Modelo Formal de Propósito Geral para Simulações de Redes Definidas por Software (2016)

Redes Definidas por Software (SDN) permitem uma maior flexibilidade na gerência de fluxos de rede devido a clara separação entre o plano de controle e o plano de dados. Nesse contexto, mensurar as características que afetam, por exemplo, o desempenho da rede é uma tarefa árdua diante de diferentes cenários, requisitos e objetivos distintos de otimização. Assim, desenvolvemos um modelo baseado no formalismo de especificação de sistemas a eventos discretos (DEVS) para que seja possível simular cenários de rede SDN de forma flexível e rápida a fim de auxiliar no entendimento do funcionamento da rede e de aspectos que podem impactar no seu desempenho. Além disso, é possível ainda avaliar estratégias de otimização que podem ser integradas ao DEVS abrindo a oportunidade para validar diversos outros trabalhos.
MCP-1 (Monocyte Chemotactic Protein-1)-induced Protein, a Recently Identified Zinc Finger Protein, Induces Adipogenesis in 3T3-L1 Pre-adipocytes without Peroxisome Proliferator-activated Receptor γ (2009)

Adipogenesis is a key differentiation process relevant to obesity and associated diseases such as type 2 diabetes. This process involves temporally regulated genes controlled by a set of transcription factors, CCAAT/enhancer-binding proteins (C/EBP) beta, C/EBPdelta, and C/EBPalpha and peroxisome proliferator-activated receptor gamma (PPARgamma). Currently, PPARgamma is universally accepted as the master regulator that is necessary and sufficient to induce adipogenesis as no known factor can induce adipogenesis without PPARgamma. We present evidence that a novel zinc finger protein, MCP-1-induced protein (MCPIP), can induce adipogenesis without PPARgamma. Classical adipogenesis-inducing medium induces MCP-1 production and expression of MCPIP in 3T3-L1 cells before the induction of the C/EBP family of transcription factors and PPARgamma. Knockdown of MCPIP prevents their expression and adipogenesis as measured by expression of adipocyte markers and lipid droplet accumulation. Treatment of 3T3-L1 cells with MCP-1 or forced expression of MCPIP induces expression of C/EBPbeta, C/EBPdelta, C/EBPalpha, and PPARgamma and adipogenesis without any other inducer. Forced expression of MCPIP induces expression of the C/EBP family of transcription factors and adipogenesis in PPARgamma(-/-) mouse embryonic fibroblasts. Thus, MCPIP is a newly identified protein that can induce adipogenesis without PPARgamma.
Gene Cluster of Arthrobacter ilicis Rü61a Involved in the Degradation of Quinaldine to Anthranilate (2003)

A genetic analysis of the anthranilate pathway of quinaldine degradation was performed. A 23-kb region of DNA from Arthrobacter ilicis Rü61a was cloned into the cosmid pVK100. Although Escherichia coli clones containing the recombinant cosmid did not transform quinaldine, cosmids harboring the 23-kb region, or a 10.8-kb stretch of this region, conferred to Pseudomonas putida KT2440 the ability to cometabolically convert quinaldine to anthranilate. The 10.8-kb fragment thus contains the genes coding for quinaldine 4-oxidase (Qox), 1H-4-oxoquinaldine 3-monooxygenase, 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase, and N-acetylanthranilate amidase. The qoxLMS genes coding for the molybdopterin cytosine dinucleotide-(MCD-), FeSI-, FeSII-, and FAD-containing Qox were inserted into the expression vector pJB653, generating pKP1. Qox is the first MCD-containing enzyme to be synthesized in a catalytically fully competent form by a heterologous host, P. putida KT2440 pKP1; the catalytic properties and the UV-visible and EPR spectra of Qox purified from P. putida KT2440 pKP1 were essentially like those of wild-type Qox. This provides a starting point for the construction of protein variants of Qox by site-directed mutagenesis. Downstream of the qoxLMS genes, a putative gene whose deduced amino acid sequence showed 37% similarity to the cofactor-inserting chaperone XdhC was located. Additional open reading frames identified on the 23-kb segment may encode further enzymes (a glutamyl tRNA synthetase, an esterase, two short-chain dehydrogenases/reductases, an ATPase belonging to the AAA family, a 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase/5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase-like protein, and an enzyme of the mandelate racemase group) and hypothetical proteins involved in transcriptional regulation, and metabolite transport.
Antibody-catalyzed bimolecular imine formation (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAntibody-catalyzed bimolecular imine formationAndrea G. Cochran, Tony Pham, Renee Sugasawara, and Peter G. SchultzCite this: J. Am. Chem. Soc. 1991, 113, 17, 6670–6672Publication Date (Print):August 1, 1991Publication History Published online1 May 2002Published inissue 1 August 1991https://pubs.acs.org/doi/10.1021/ja00017a046https://doi.org/10.1021/ja00017a046research-articleACS PublicationsRequest reuse permissionsArticle Views209Altmetric-Citations45LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
ChemInform Abstract: Casuarine: A Very Highly Oxygenated Pyrrolizidine Alkaloid (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Pulmonary Cryptococcosis in Solid Organ Transplant Recipients: Clinical Relevance of Serum Cryptococcal Antigen (2007)

A positive serum cryptococcal antigen test result in SOT recipients with pulmonary cryptococcosis appears to reflect extrapulmonary or more advanced radiographic disease.
Physiological Micromechanics of the Anterior Mitral Valve Leaflet (2011)

An improved understanding of mitral valve (MV) function remains an important goal for determining mechanisms underlying valve disease and for developing novel therapies. Critical to heart valve tissue homeostasis is the valvular interstitial cells (VICs), which reside in the interstitium and maintain the extracellular matrix (ECM) through both protein synthesis and enzymatic degradation [1]. There is scant experimental data on the alterations of the MV fiber network reorganization as a function of load, which is critical for implementation of computational strategies that attempt to link this meso-micro scale phenomenon. The observed large scale deformations experienced by VICs could be implicated in mechanotransduction [2], i.e., translation of mechanical stimuli into biochemical signals. Consequently, our goal is to quantitatively connect organ level loads to cellular deformation as a function of the ECM fiber network. We hypothesize that cellular deformations are likely a complex function of collagen and elastin fiber mechanical properties, architecture, and cellular coupling to these fibers.