gebhart/patrepeval huggingface dataset:
A tunable 1x4 silicon CMOS photonic wavelength multiplexer/demultiplexer for dense optical interconnects (2010)

We report the first compact silicon CMOS 1x4 tunable multiplexer/ demultiplexer using cascaded silicon photonic ring-resonator based add/drop filters with a radius of 12 microm, and integrated doped-resistor thermal tuners. We measured an insertion loss of less than 1 dB, a channel isolation of better than 16 dB for a channel spacing of 200 GHz, and a uniform 3 dB pass band larger than 0.4 nm across all four channels. We demonstrated accurate channel alignment to WDM ITU grid wavelengths using integrated silicon heaters with a tuning efficiency of 90 pm/mW. Using this device in a 10 Gbps data link, we observed a low power penalty of 0.6 dB.
Determination of liquidus temperature in Ti-rich alloys of the Fe–Ni–Ti system obtained by DTA, electrical conductivity and XRD measurements (2011)

Abstract Despite its significant technical relevance, a number of uncertainties remain regarding the Fe–Ni–Ti ternary system. These concern phase relations, the solidus–liquidus range and the liquidus projection, especially in the Ti-rich corner. In this study the melting and solidification behaviour of Tirich Fe–Ni–Ti alloys was characterized using differential thermal analysis, electrical conductivity measurements and high-temperature X-ray diffraction. Combining these different methods allowed us to determine the liquidus temperatures more precisely than with differential thermal analysis measurements alone. The results were compared with calculated values using the ThermoCalc software package.
Sub-fs timing jitter of an 88 fs all-PM fiber integrated ultrafast Yb NALM oscillator (2021)

We demonstrate an all-PM fiber integrated femtosecond Yb NALM oscillator with 88 fs compressed pulse duration and sub-fs free-running timing jitter [25 kHz to 5 MHz].
Video 2 from A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors (2023)

&lt;p&gt;Representative videos of intravital two-photon (2P) microscopy of tumors treated with CEA TCB. Tumor cells red, T cells green.&lt;/p&gt;
Supplementary Figures 1 and 2, Table 1 from Degradation of Fibrillar Collagen in a Human Melanoma Xenograft Improves the Efficacy of an Oncolytic Herpes Simplex Virus Vector (2023)

Supplementary Figures 1 and 2, Table 1 from Degradation of Fibrillar Collagen in a Human Melanoma Xenograft Improves the Efficacy of an Oncolytic Herpes Simplex Virus Vector
Association between mechanical stress and bone remodeling. (1990)

Stress patterns and levels were analyzed by use of the three-dimensional finite element method. Three-dimensional models were constructed for the human upper central incisor (1205 nodes and 920 elements) and the sheep metacarpus (240 nodes and 128 elements). Orthodontic and orthopedic forces were applied to the tooth and the bone, simulating orthodontic tooth movement and experimental loading test for the bone. Three principal stresses were determined in the alveolar bone and the sheep long bone. The following results were obtained. 1. Stress distributions in the lateral alveolar bone were similar to those with bone deformation from cantilever bending mode. On the medial surface of the alveolar bone, a bending stress was observed, however, remaining stresses exhibited changes corresponding to those in the PDL produced by tipping displacement of the tooth. 2. In the sheep long bone, tensile and compressive stresses were induced on the dorsal and volar sides, respectively. The magnitude of stresses was greatest at the mid-diaphyseal region. Compressive and tensile stresses were related with bone resorption and apposition. The magnitude of principal stresses was almost proportional to dimensional changes of the bone at the mid-diaphyseal region. Bone remodeling in the long bone is related with mechanical stress, principal stress in particular, indicating that remodeling of the alveolar bone may be induced by application of orthodontic force in addition to conventional change of the bone adjacent to the PDL. Thus, it is shown that mechanical stress in living structures may be a trigger to induce biological remodeling of bones.
Optimal and suboptimal relay selection and power allocation in multi-relay cooperative network (2011)

We study a cooperative communication scenario where multiple amplify-and-forward relays cooperate to transmit data from a source to destination. We discuss an optimal power allocation method to assign transmit powers to the source and relays in order to maximize achievable data rate of the system.We also propose less-complex suboptimal power allocation methods using various relay selection strategies. We provide simulation results to demonstrate performance of the optimal power allocation and suboptimal relay selection and power allocation schemes. We show that these suboptimal schemes perform close to optimal scheme and are more reasonable for practical implementation.
Ten-Year Comparison Study of Type 1 and 2 Endometrial Cancers: Risk Factors and Outcomes (2019)

Consistent with previous literature, our analysis found that type 2 cancer is more common in non-white, older, and less obese patients and associated with higher mortality and recurrence. However, inconsistent with previous literature, we found no association between type 2 cancer and diabetes mellitus or use of HRT. These factors should be considered when approaching patients with endometrial cancer.
Materials and thermal stability of tantalum carbide layers for metal gate applications (2006)

Phase compositions and thermal stability of different TaC <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x </sub> layers deposited by PVD is studied using in-situ high-temperature XRD (HT-XRD). It is found that the phase composition of the as-dep. layers and those during annealing at high temperatures strongly depends on their chemical compositions. Low carbon layers (~Ta <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">4</sub> C) are amorphous below 700degC, and crystallize into hexagonal Ta <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> C in 700-900degC. At 1150degC, the Ta <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> C is replaced by TaSi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> . Stoichiometric Ta <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> C are also dominantly amorphous below 900degC and starts to form cubic TaC at 900degC, and TaSi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> at 1100degC. The as-dep. TaC layers are crystalline, with a dominant cubic TaC phase. At 1000degC, the TaC is replaced by TaSi <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub>
High‐Throughput Aging System for Parallel Maximum Power Point Tracking of Perovskite Solar Cells (2022)

In this research instrument article, the capabilities and details of a high‐throughput aging system for parallel maximum power point tracking (MPPT) of perovskite solar cells (PSCs), capable of assessing the operational stability of a large number of devices, are presented. The intention is to provide insights into the machine and the development process to engineers who want to create a similar system and eventually make MPPT stability testing of PSCs a standard procedure.
Formation of Formic Acid by Hydrothermal Oxidation of Carbohydrate Biomass for Producing Hydrogen (2008)

The formation of formic acid by hydrothermal oxidation of glucose, a model compound of carbohydrate biomass, was investigated for applying formic acid as a source of hydrogen production. All experiments were conducted in a batch reactor made of SUS 316 tubing, providing an internal volume of 5.7 cm3. A 30 wt% hydrogen peroxide solution was used as an oxidant. The hydrothermal oxidation of glucose with and without the addition of alkali was carried out with temperature varying from 250 to 300 °C, reaction time varying from 30 s to 90 s, and H2O2 supply varying from 80% to 140%. Results showed that at a mild temperature of 250 °C, glucose was converted into formic acid in an excellent yield of 75% when adding alkali. This result should facilitate the study on the production of hydrogen from carbohydrate biomass via formic acid.
ASXL1 but Not TET2 Mutations Adversely Impact Overall Survival of Patients Suffering Systemic Mastocytosis with Associated Clonal Hematologic Non-Mast-Cell Diseases (2014)

Systemic mastocytosis with associated hematologic clonal non-mast cell disease (SM-AHNMD) is a rare and heterogeneous subtype of SM and few studies on this specific entity have been reported. Sixty two patients with Systemic mastocytosis with associated hematologic clonal non-mast cell disease (SM-AHNMD) were presented. Myeloid AHNMD was the most frequent (82%) cases. This subset of patients were older, had more cutaneous lesions, splenomegaly, liver enlargement, ascites; lower bone mineral density and hemoglobin levels and higher tryptase level than lymphoid AHNMD. Defects in KIT, TET2, ASXL1 and CBL were positive in 87%, 27%, 14%, and 11% of cases respectively. The overall survival of patients with SM-AHNMD was 85.2 months. Within the myeloid group, SM-MPN fared better than SM-MDS or SM-AML (p = 0.044,). In univariate analysis, the presence of C-findings, the AHNMD subtypes (SM-MDS/CMML/AML versus SM-MPN/hypereosinophilia) (p = 0.044), Neutropenia (p = 0.015), high monocyte level (p = 0.015) and the presence of ASXL1 mutation had detrimental effects on OS (p = 0.007). In multivariate analysis and penalized Cox model, only the presence of ASXL1 mutation remained an independent prognostic factor that negatively affected OS (p = 0.035). SM-AHNMD is heterogeneous with variable prognosis according to the type of the AHNMD. ASXL1 is mutated in a subset of myeloid AHNMD and adversely impact on OS.
Emended description of the genus Actinokineospora Hasegawa 1988 and transfer of Amycolatopsis fastidiosa Henssen et al. 1987 as Actinokineospora fastidiosa comb. nov. (2009)

The species Amycolatopsis fastidiosa (ex Celmer et al. 1977) Henssen et al. 1987 was proposed, based on morphological and chemotaxonomic observations, for a strain originally described as 'Pseudonocardia fastidiosa' Celmer et al. 1977 in a US patent. In the course of a phylogenetic study of the taxa with validly published names within the suborder Pseudonocardineae based on 16S rRNA gene sequences, it became apparent that this species was misplaced in the genus Amycolatopsis. After careful evaluation of the phylogeny, morphology, chemotaxonomy and physiology of the type strain, it was concluded that this strain represents a species of the genus Actinokineospora that is unable to produce motile spores. The description of the genus Actinokineospora is therefore emended to accommodate species that do not produce motile spores, and it is proposed that Amycolatopsis fastidiosa be transferred to the genus Actinokineospora as Actinokineospora fastidiosa comb. nov. The type strain is NRRL B-16697(T) =ATCC 31181(T) =DSM 43855(T) =JCM 3276(T) =NBRC 14105(T) =VKM Ac-1419(T).
A Compact GNLTL Using Permanent Magnet Rings With Improved H-field Uniformity (2022)

There has been a great interest in using compact gyromagnetic nonlinear transmission lines (GNLTLs) for applications in defense platforms, radars, and space as pulsed RF transmitting sources. The reason is that the GNLTL is all solidstate and does not require the vacuum and thermionic electron guns as power electronic tubes do. Since GNLTS employ axial magnetic bias, permanent magnets can replace the solenoid to reduce weight and size. The best alternative for this is to use neodymium rings along the line. Then, in this work, we will present the results obtained with a bench-compact line using a small number of magnets, instead of a solenoid, driven by a Gaussian shape input pulse in the range of 6–12 kV and with a width of about 15 ns.
Brain Tumor Cells in Circulation Are Enriched for Mesenchymal Gene Expression (2014)

GBMs are locally invasive within the brain but rarely metastasize to distant organs, exemplifying the debate over "seed" versus "soil." We demonstrate that GBMs shed CTCs with invasive mesenchymal characteristics into the circulation. Rare metastatic GBM lesions are primarily mesenchymal and show additional mutations absent in the primary tumor.
Facile fabrication of superhydrophobic coatings on concrete substrate (2021)

Purpose The purpose of this study is to prepare a chemically stable superhydrophobic coating with remarkable mechanical properties and concrete protective properties. Design/methodology/approach One synthetic step was adopted to prepare superhydrophobic coating. The process and product were analyzed and confirmed by fourier transform-infrared spectroscopy (FT-IR), thermogravimetric analysis (TGA), water contact angle (WCA), transmission electron microscopy (TEM), scanning electron microscope (SEM), X-ray diffraction (XRD), and X-ray photoelectron spectroscopy (XPS). The mechanical properties were confirmed by tensile test. The concrete protective properties were confirmed by solution immersion test and rapid chloride migration coefficient test. Findings MSiO 2 nanoparticles (NPs) were chosen to enhance the hydrophobicity of fluorosilicone coatings. With a 4:1 mass ratio of fluorosilicone resin and MSiO 2 NPs, the coatings show superhydrophobicity with a WCA of 156° and a SA of 3.1°. In addition, the tensile mechanical property was improved, and the chloride ion diffusion coefficient was decreased significantly after the addition of MSiO 2 NPs. Practical implications This new fluorosilicone coating hybrid by MSiO 2 NPs could be applied as a concrete protective layer with properties of self-cleaning, antifouling, etc. Originality/value Introduction of MSiO 2 NPs hybrid to prepare fluorosilicone coating with superhydrophobicity on concrete surface has not been systematically studied previously.
Optimization of wavelength tuning of erbium-doped fiber ring lasers (1996)

The dynamics of erbium-doped fiber ring lasers undergoing wavelength tuning is examined. The relaxation oscillations and mode build-up time are characterized. An all-optical damping technique which is capable of complete elimination of relaxation oscillations is analyzed, and measurements on a tunable erbium-doped fiber lasers are reported. An analytical solution is derived for the mode build-up time of tunable fiber lasers. Limiting parameters for the design of a high-speed tunable fiber laser are identified. An equalization technique for obtaining uniform switching speed is described.
Growth-related stress and surface morphology in homoepitaxial SrTiO3 films (1996)

The lattice parameter and surface morphology of homoepitaxial SrTiO3 films were found to depend on the ambient oxygen pressure during growth. The homoepitaxial layers were grown by pulsed laser deposition with static ambient oxygen pressures of 100, 10, and 1 mTorr. The surface roughness of the films increased with increasing ambient growth pressure. In each case, the measured out-of-plane lattice parameter of the film was larger than that of the substrate. The mismatch between film and substrate increased with decreasing growth pressure. Compressive stresses of ∼0.28, 1.2, and 2.0 GPa were determined for homoepitaxial SrTiO3 layers deposited at 100, 10, and 1 mTorr, respectively.
ChemInform Abstract: Synthesis and Evaluation of a Series of 3,5‐Disubstituted Benzisoxazole‐4,7‐diones. Potent Radiosensitizers in vitro. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Ação local do alendronato sódico na reparação óssea de ratos espontaneamente hipertensos (SHR) (2008)

The administration of sodium alendronate did not contribute to bone repair in SHR rat, but possibly has been responsible for the extracortical bone formation observed.
Device and Equipment Evaluations (2004)

Device evaluation, which is an essential skill set for the respiratory therapist, ranges from comparing manufacturer's specifications to comprehensive device testing, either with patients or on the bench. Good device evaluations help guide decisions about device selection, procedure development, and risk and failure analysis. Poor evaluations cost time and money and fail to return value. Manufacturer's specifications alone are poor criteria for device selection, because of how and why those specifications are created and the potential gap between the manufacturer's test methods and the complexity of clinical situations. Proper clinical evaluation of devices with patients requires extensive preparation and resource expenditure, and clinical evaluations may not allow isolating key variables to determine specifics of device performance. In vitro testing, using models to simulate discrete components of device/patient interface, is less expensive and easier to conduct. This article discusses the process of experiment design and model development for device and equipment evaluations.
Circuits and Systems for Wireless Body Area Network (2016)

This chapter focuses on the implementation of the Things-oriented medical body area network (MBAN) system which sheds new light on the short-range connectivity among various physiological sensors and wearable devices carried by human bodies for a continuous and ambulatory connection. It describes an energy-efficient MBAN system for mobile healthcare applications that has been implemented with crystal-less compact wearable and implantable sensor nodes. With regard to the MBAN sensor nodes, energy-efficient wireless technologies are a major design challenge that will extend the lifetime of the nodes under limited energy sources. The frequency calibration method utilized effectively eliminates the crystal oscillator (XO) in the sensor nodes with the help of the reference signal from the hub. The low power circuit techniques for the sensors and hub transceiver were introduced in our previous research. The prototype MBAN system was implemented to verify the proposed system, and the successful measurement results were provided.
Real-time physical random bit generation at Gbps based on random fiber lasers (2017)

We demonstrate for the first time, to the best of our knowledge, a high-speed physical random bit generator at gigabits/second without the time-delay signature based on chaotic power fluctuations of a random fiber laser. The random fiber laser is configured using a ring structure with semiconductor optical amplifiers as the optical gain and a fiber random grating as the random feedback medium. The long-length ring cavity provides a large number of densely spaced cavity modes that co-exist within the gain bandwidth tailored by the optical filter. Unlike fixed cavity modes in conventional fiber ring lasers, these modes are less phase-correlated due to the random distributed feedback from the fiber random grating fabricated by a plane-by-plane inscription technique without phase control, leading to intensified lasing output fluctuations with high-dimensional chaotic dynamic natures without specific cavity features, when the random fiber laser is operated slightly above the lasing threshold. Random bit generation at a bit rate up to ∼1.6 Gbps is achieved with verified randomness through standard tests. Different from the previously reported schemes requiring offline post-processing procedures, this physical random number generator can function in real time, offering high-quality randomness and security assurance for pertinent applications.
Anticipating annotations and emerging trends in biomedical literature (2008)

The BioJournalMonitor is a decision support system for the analysis of trends and topics in the biomedical literature. Its main goal is to identify potential diagnostic and therapeutic biomarkers for specific diseases. Several data sources are continuously integrated to provide the user with up-to-date information on current research in this field. State-of-the-art text mining technologies are deployed to provide added value on top of the original content, including named entity detection, relation extraction, classification, clustering, ranking, summarization, and visualization. We present two novel technologies that are related to the analysis of temporal dynamics of text archives and associated ontologies. Currently, the MeSH ontology is used to annotate the scientific articles entering the PubMed database with medical terms. Both the maintenance of the ontology as well as the annotation of new articles is performed largely manually. We describe how probabilistic topic models can be used to annotate recent articles with the most likely MeSH terms. This provides our users with a competitive advantage because, when searching for MeSH terms, articles are found long before they are manually annotated. We further present a study on how to predict the inclusion of new terms in the MeSH ontology. The results suggest that early prediction of emerging trends is possible. The trend ranking functions are deployed in our system to enable interactive searches for the hottest new trends relating to a disease.
Psychiatric manifestations revealing inborn errors of metabolism in adolescents and adults (2007)

Inborn errors of metabolism (IEMs) may present in adolescence or adulthood as a psychiatric disorder. In some instances, an IEM is suspected because of informative family history or because psychiatric symptoms form part of a more diffuse clinical picture with systemic, cognitive or motor neurological signs. However, in some cases, psychiatric signs may be apparently isolated. We propose a schematic classification of IEMs into three groups according to the type of psychiatric signs at onset. Group 1 represents emergencies, in which disorders can present with acute and recurrent attacks of confusion, sometimes misdiagnosed as acute psychosis. Diseases in this group include urea cycle defects, homocysteine remethylation defects and porphyrias. Group 2 includes diseases with chronic psychiatric symptoms arising in adolescence or adulthood. Catatonia, visual hallucinations, and aggravation with treatments are often observed. This group includes homocystinurias, Wilson disease, adrenoleukodystrophy and some lysosomal disorders. Group 3 is characterized by mild mental retardation and late-onset behavioural or personality changes. This includes homocystinurias, cerebrotendinous xanthomatosis, nonketotic hyperglycinaemia, monoamine oxidase A deficiency, succinic semialdehyde dehydrogenase deficiency, creatine transporter deficiency, and alpha and beta mannosidosis. Because specific treatments should be more effective at the 'psychiatric stage' before the occurrence of irreversible neurological lesions, clinicians should be aware of atypical psychiatric symptoms or subtle organic signs that are suggestive of an IEM. Here we present an overview of IEMs potentially revealed by psychiatric problems in adolescence or adulthood and provide a diagnostic strategy to guide metabolic investigations.