gebhart/patrepeval huggingface dataset:
Experiments in free-space triangulation using cooperative localization (2004)

This paper presents a first detailed case study of collaborative exploration of a substantial environment. We use a pair of cooperating robots to test multi-robot environment mapping algorithms based on triangulation of free space. The robots observe one another using a robot tracking sensor based on laser range sensing (LIDAR). The environment mapping itself is accomplished using sonar sensing. The results of this mapping are compared to those obtained using scanning laser range sensing and the scan matching algorithm. We show that with appropriate outlier rejection policies, the sonar-based map obtained using collaborative localization can be as good or, in fact, better than that obtained using what is typically considered to be a superior sensing technology.
Microstructures électrostatiques de récupération d'énergie vibratoire pour les microsystèmes (2010)

MEMS (Micro-Electro-Mechanical Systems) are present in many fields such as transportation, defense and telecommunications... and can, with small dimensions, perform functions of sensors and actuators. To do so, MEMS require a source of energy. So far, this function is provided by batteries whose main fault is the limited lifetime. One solution is to harvest energy in the immediate vicinity of the microsystem. Here we focus on the harvesting of vibrational energy by electrostatic systems, and present the principles of conversion and a state of the art.
p47 phox Is Required for Afferent Arteriolar Contractile Responses to Angiotensin II and Perfusion Pressure in Mice (2011)

Myogenic and angiotensin contractions of afferent arterioles generate reactive oxygen species. Resistance vessels express neutrophil oxidase-2 and -4. Angiotensin II activates p47(phox)/neutrophil oxidase-2, whereas it downregulates NOX-4. Therefore, we tested the hypothesis that p47(phox) enhances afferent arteriolar angiotensin contractions. Angiotensin II infusion in p47(phox) +/+ but not -/- mice increased renal cortical NADPH oxidase activity (7±1-12±1 [P<0.01] versus 5±1-7±1 10(3) · RLU · min(-1) · μg protein(-1) [P value not significant]), mean arterial pressure (77±2-91±2 [P<0.005] versus 74±2-77±1 mm Hg [P value not significant]), and renal vascular resistance (7.5±0.4-10.1±0.7 [P<0.01] versus 7.9±0.4-8.3±0.4 mm Hg/mL · min(-1) · gram kidney weight(-1) [P value not significant]). Afferent arterioles from p47(phox) -/- mice had a lesser myogenic response (3.1±0.4 versus 1.4±0.2 dynes · cm(-1) · mm Hg(-1); P<0.02) and a lesser (P<0.05) contraction to 10(-6) M angiotensin II (diameter change +/+: 9.3±0.2-3.4±0.6 μm versus -/-: 9.9±0.6-7.5±0.4 μm). Angiotensin and increased perfusion pressure generated significantly (P<0.05) more reactive oxygen species in p47(phox) +/+ than -/- arterioles. Angiotensin II infusion increased the maximum responsiveness of afferent arterioles from p47(phox) +/+ mice to 10(-6) M angiotensin II yet decreased the response in p47(phox) -/- mice. The angiotensin infusion increased the sensitivity to angiotensin II only in p47(phox) +/+ mice. We conclude that p47(phox) is required to enhance renal NADPH oxidase activity and basal afferent arteriolar myogenic and angiotensin II contractions and to switch afferent arteriolar tachyphylaxis to sensitization to angiotensin during a prolonged angiotensin infusion. These effects likely contribute to hypertension and renal vasoconstriction during infusion of angiotensin II.
Ultrasonic image formation: implications for the image processing practitioner (2002)

This paper provides an overview of how ultrasound images are acquired and processed in typical commercial equipment, with emphasis on implications for image processing. We begin with a brief discussion of relevant acoustic theory, concentrating on bulk interaction of acoustic waves with tissue. We then discuss different transducer designs and their implications for image quality. Transmit and receive beam formation is discussed, including-the effects of transmit focus, receive focus, and time-multiplex techniques. Typical signal processing techniques used on the beamformed signal are discussed, along with the effect of operator controls. With this system description in hand, we conclude by examining overall clinical image duality. Typical image artifacts, including sidelobes, grating lobes, reverberation, range ambiguity, speckle, shadowing, and dropout are discussed.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Noncontact wafer doping maps measured with T-rays (1996)

Summary form only given. Recently, Hu and Nuss demonstrated an imaging system using THz transients generated by standard optoelectronic methods. We have used this system to measure spatial inhomogeneities in the doping density of epitaxial GaAs films. The absorption of THz radiation by doped semiconductors is a strong function of the conductivity, and as a result we are able to detect small variations in the level of doping with 250-/spl mu/m spatial resolution. Such information is not easily obtainable by any other method, and this demonstration could lead to improved quality control in the growth of doped semiconductor wafers.
Home treatment of patients with cancer-associated venous thromboembolism – An evaluation of daily practice (2019)

Two-third of patients with cancer-associated VTE - including PE - were selected to start anticoagulant treatment at home. Cancer-associated VTE is associated with high rates of VTE-related adverse events independent of initial in hospital or home treatment. However, home treatment may be a good option for selected patients with cancer-associated DVT or PE.
Smooth Muscle Cell Seeding on Decellularized Porcine Saphenous Vein Scaffolds –A Step Towards Functional Tissue Engineered Blood Vessels (2009)

The need for improved autologous tissue engineered blood vessels (TBEV) for vascular replacement is unequivocal. To this end, the over‐riding goal of our vascular research program is to develop TEBV that more closely approximate native vasculature. To this end, we have utilized an approach that combines dual‐seeding of endothelial and smooth muscle cells on decellularized arterial scaffolds (DAS) followed by bioreactor preconditioning. A major barrier to this approach is the limited migration of SMC into the medial layer of the DAS. To overcome this limitation, the current studies explored the potential of decellularized venous scaffolds (DVS). DVS were statically seeded with SMC for 2 hours and preconditioned in a bioreactor with either pulsatile flow (60 bpm /80‐120 mm Hg) or steady flow (100 mm Hg) for two weeks. The effect of cyclic strain preconditioning on attachment, proliferation and migration of SMCs was evaluated with H&amp;E, Trichrome and DAPI. Our preliminary data suggest that seeded SMC adhere to and proliferate on DVS. We also demonstrated that cyclic preconditioning using pulsatile flow improves SMC migration and integration/ingrowth into the medial layer of the scaffold. Although further study is required, these initial data are encouraging and indicate that in vitro conditioning of DVS may produce TEBV that more closely mimic the architecture and physiological characteristics of native arteries.
Ultrasonic Velocities Measurement in Compacted Bentonite-Sand Mixtures for Saturation Level Evaluation (2018)

Compacted bentonite materials are often considered as a buffer material in the geological radioactive waste disposal. This bentonite is expected to fill up the space between the waste and the surrounding ground by swelling. Therefore, understanding the surrounding ground, i.e., groundwater behavior in bentonite, as a buffer material, is essential in order to evaluate the bentonite buffer performance and guarantee long-term safety. The monitoring system of the water saturation level in compacted bentonite is required because water content in buffer material may influence its elastic properties. In this study, the correlation between water content and elasticity in unsaturated compressed bentonite was experimentally evaluated. The evaluation was done by measuring the sound velocity of both longitudinal wave and transverse wave. As a result, it can be confirmed that ultrasonic velocities could evaluate a degree of saturation and bulk modulus of compacted bentonite.
Measurement of the nonlinear elasticity of red blood cell membranes (2011)

The membranes of human red blood cells (RBCs) are a composite of a fluid lipid bilayer and a triangular network of semiflexible filaments (spectrin). We perform cellular microrheology using the dynamic membrane fluctuations of the RBCs to extract the elastic moduli of this composite membrane. By applying known osmotic stresses, we measure the changes in the elastic constants under imposed strain and thereby determine the nonlinear elastic properties of the membrane. We find that the elastic nonlinearities of the shear modulus in tensed RBC membranes can be well understood in terms of a simple wormlike chain model. Our results show that the elasticity of the spectrin network can mostly account for the area compression modulus at physiological osmolality, suggesting that the lipid bilayer has significant excess area. As the cell swells, the elastic contribution from the now tensed lipid membrane becomes dominant.
The IL‐13/periostin/IL‐24 pathway causes epidermal barrier dysfunction in allergic skin inflammation (2018)

The IL-13/periostin pathway induces IL-24 production in keratinocytes, playing an important role in barrier dysfunction in AD.
High‐stability optical frequency transfer with all‐fiber architecture for optical lattice clocks (2019)

Abstract We have developed a laser distributor for highly accurate optical frequency transfer of optical lattice clocks. Each output has a phase stabilizer based on a Michelson interferometer with all‐fiber architecture. Varying the optical path length in the residual uncontrolled optical path to introduce phase noises between output branches, we found the residual frequency transfer instability to be much smaller than the frequency instability of current optical lattice clocks. All fiber configuration provides robustness, which allows optical lattice clocks to be used in wide range of applications not only in a laboratory, but also outside laboratory, for example, geodetic applications.
Synthetic Silicate Zeolites: Diverse Materials Accessible through Geoinspiration (2010)

This chapter contains sections titled: Introduction Zeolites: Some Definitions Zeolite Structures Chemical Composition of Silicate Zeolites Zeolite Properties Zeolite Applications Zeolite Synthesis Concluding Remarks Acknowledgements References
Un système avancé de gestion d'énergie dans le bâtiment pour coordonner production et consommation (2007)

This PhD thesis contributes to the power management in buildings. It is shown that, by providing appliances with optimization algorithms and communication abilities, it is possible to improve energy consumption and production in buildings by exploiting the degrees of freedom coming from user requests and appliance behaviors. A mathematical formulation and a multi-layer control architecture composed of three layers: predictive, reactive and local layers, are proposed in order to optimize user's comfort, economical and environmental criterion. Different solving approaches based on hybrid metaheuristics and dynamic programming are proposed. A multi-parametric programming is used to take into account big uncertainties. It has been applied to the power management of a photovoltaic building and to the prevention of blackouts using sets of buildings equipped with intelligent and communicating home automation systems.
Asymmetric Dimethylarginine and Reactive Oxygen Species (2012)

Plasma levels of asymmetric dimethylarginine or markers of reactive oxygen species are increased in subjects with risk factors for cardiovascular disease or chronic kidney disease. We tested the hypothesis that reactive oxygen species generate cellular asymmetric dimethylarginine that together cause endothelial dysfunction that underlies the risk of subsequent disease. Rat preglomerular vascular smooth muscle cells transfected with p22(phox) had increased NADPH oxidase activity, enhanced activity and expression of protein arginine methyltransferase, and reduced activity and protein expression of dimethylarginine dimethylaminotransferase and of cationic amino acid transferase 1 resulting in increased cellular levels of asymmetric dimethylarginine. Rats infused with angiotensin II had oxidative stress. The endothelial function of their mesenteric arterioles was changed from vasodilatation to vasoconstriction, accompanied by increased vascular asymmetric dimethylarginine. All of these changes were prevented by Tempol. In vivo silencing of dimethylarginine dimethylaminotransferase 1 increased plasma levels of asymmetric dimethylarginine, whereas silencing of dimethylarginine dimethylaminotransferase 2 impaired endothelial function. We suggest that initiation factors, such as angiotensin II, expressed in blood vessels or tissues of subjects with cardiovascular and kidney disease risk factors generate reactive oxygen species from NADPH oxidase that enhances cellular asymmetric dimethylarginine in an amplification loop. This leads to adverse changes in vascular and organ functions, as a consequence of reduced tissue levels of NO and increased reactive oxygen species. Thus, we conclude that reactive oxygen species and asymmetric dimethylarginine form a tightly coupled amplification system that translates cardiovascular/kidney risk into overt disease.
Two-Cation Competition in Ionic-Liquid-Modified Electrolytes for Lithium Ion Batteries (2005)

It is a common observation that when ionic liquids are added to electrolytes the performances of lithium ion cells become poor, while the thermal safeties of the electrolytes might be improved. In this study, this behavior is investigated based on the kinetics of ionic diffusion. As a model ionic liquid, we chose butyldimethylimidazolium hexafluorophosphate (BDMIPF(6)). The common solvent was propylene carbonate (PC), and lithium hexafluorophosphate (LiPF(6)) was selected as the lithium conducting salt. Ionic diffusion coefficients are estimated by using a pulsed field gradient NMR technique. From a basic study on the model electrolytes (BDMIPF(6) in PC, LiPF(6) in PC, and BDMIPF(6) + LiPF(6) in PC), it was found that the BDMI(+) from BDMIPF(6) shows larger diffusion coefficients than the Li(+) from LiPF(6). However, the anionic (PF(6)(-)) diffusion coefficients present little difference between the model electrolytes. The higher diffusion coefficient of BDMI(+) than that of Li(+) suggests that the poor C-rate performance of lithium ion cells containing ionic liquids as an electrolyte component can be attributed to the two-cation competition between Li(+) and BDMI(+).
Small-Size Tapered Slot Antenna (TSA) Design for use in 5G Phased Array Applications (2017)

The design and development of a compact tapered slot antenna (TSA) for the fifth generation (5G) phased array communications is described in this manuscript. The proposed low-profile TSA element is designed on a Rogers RT 5880 (?=2.2 and ?=0.0009) dielectric to work in the frequency range from 21 to 23 GHz. The configuration of the employed TSA antenna elements is composed of a slot-line flare from a small gap to a large opening, matching to free space’s wave impedance. Eight TSA elements with well-defined endfire radiation patterns have been used on the top portion of a mobile-phone PCB to form a 1×8 linear phased array. The TSA elements are fed by hockey-stick baluns. In addition, the radiation performance and SAR characteristics of the phased array 5G antenna in the vicinity of user’s hand & head have been investigated in this study. The results show that the proposed design provides good characteristics in terms of S-parameters, antenna gain, efficiency, SAR, and beam steering, which fit the need of 5G cellular communications.
Host and microbiome features of secondary infections in lethal covid-19 (2022)

Secondary infections contribute significantly to covid-19 mortality but driving factors remain poorly understood. Autopsies of 20 covid-19 cases and 14 controls from the first pandemic wave complemented with microbial cultivation and RNA-seq from lung tissues enabled description of major organ pathologies and specification of secondary infections. Lethal covid-19 segregated into two main death causes with either dominant diffuse alveolar damage (DAD) or secondary pneumonias. The lung microbiome in covid-19 showed a reduced biodiversity and increased prototypical bacterial and fungal pathogens in cases of secondary pneumonias. RNA-seq distinctly mirrored death causes and stratified DAD cases into subgroups with differing cellular compositions identifying myeloid cells, macrophages and complement C1q as strong separating factors suggesting a pathophysiological link. Together with a prominent induction of inhibitory immune-checkpoints our study highlights profound alterations of the lung immunity in covid-19 wherein a reduced antimicrobial defense likely drives development of secondary infections on top of SARS-CoV-2 infection.
Comparison of uniaxial and polyaxial suspended germanium bridges in terms of mechanical stress and thermal management towards a CMOS compatible light source (2019)

Germanium (Ge) is a promising candidate for a CMOS compatible laser diode.This is due to its compatibility with Silicon (Si) and its ability to be converted into a direct band gap material by applying tensile strain. In particular uniaxial suspended Ge bridges have been extensively explored due to their ability to introduce high tensile strain. There have been two recent demonstrations of low-temperature optically-pumped lasing in these bridges but no room temperature operation accredit to insufficient strain and poor thermal management. In this paper we compare uniaxial bridges with polyaxial bridges in terms of mechanical stress and thermal management using Finite Element Modelling (FEM). The stress simulations reveal that polyaxial bridges suffer from extremely large corner stresses which prevent larger strain from being introduced compared with uniaxial bridges. Thermal simulations however reveal that they are much less thermally sensitive than uniaxial bridges which may indicate lower optical losses. Bridges were fabricated and Raman spectroscopy was used to validate the results of the simulations. We postulate that polyaxial bridges could offer many advantages over their uniaxial counterparts as potential laser devices
Measurements of the total cross sections for positron-He scattering using an electrostatic high-brightness slow positron beam apparatus (2009)

A magnetic field-free slow positron beam apparatus has been developed for the studies of positron scattering from atoms and molecules. It uses electrostatic lens elements and a remoderator in a reflection geometry for the brightness enhancement. The preliminary results of the total cross sections for positron-He scattering in the energy range up to 100 eV are presented.
Dosage Effects of Cohesin Regulatory Factor PDS5 on Mammalian Development: Implications for Cohesinopathies (2009)

Cornelia de Lange syndrome (CdLS), a disorder caused by mutations in cohesion proteins, is characterized by multisystem developmental abnormalities. PDS5, a cohesion protein, is important for proper chromosome segregation in lower organisms and has two homologues in vertebrates (PDS5A and PDS5B). Pds5B mutant mice have developmental abnormalities resembling CdLS; however the role of Pds5A in mammals and the association of PDS5 proteins with CdLS are unknown. To delineate genetic interactions between Pds5A and Pds5B and explore mechanisms underlying phenotypic variability, we generated Pds5A-deficient mice. Curiously, these mice exhibit multiple abnormalities that were previously observed in Pds5B-deficient mice, including cleft palate, skeletal patterning defects, growth retardation, congenital heart defects and delayed migration of enteric neuron precursors. They also frequently display renal agenesis, an abnormality not observed in Pds5B(-/-) mice. While Pds5A(-/-) and Pds5B(-/-) mice die at birth, embryos harboring 3 mutant Pds5 alleles die between E11.5 and E12.5 most likely of heart failure, indicating that total Pds5 gene dosage is critical for normal development. In addition, characterization of these compound homozygous-heterozygous mice revealed a severe abnormality in lens formation that does not occur in either Pds5A(-/-) or Pds5B(-/-) mice. We further identified a functional missense mutation (R1292Q) in the PDS5B DNA-binding domain in a familial case of CdLS, in which affected individuals also develop megacolon. This study shows that PDS5A and PDS5B functions other than those involving chromosomal dynamics are important for normal development, highlights the sensitivity of key developmental processes on PDS5 signaling, and provides mechanistic insights into how PDS5 mutations may lead to CdLS.
De novo design of ligands for metal separation. 1998 annual progress report (1998)

'Develop computer-aided molecular design technology for ligands useful in metal separations. This includes force field parameterization of different metals in various oxidation states and de novo design of ligands optimized for specific metals including constriants to certain chemical classes of ligands. This report summarizes year two of a 3-year project and focuses on force field parameterization. Work continues on the modification of algorithms to construct metal-binding ligands from molecular fragments. The lack of an appropriate theoretically derived functional form for d-orbitals in molecular mechanics has hampered efforts to utilize these programs and the efforts have focused on correcting this deficiency.'