gebhart/patrepeval huggingface dataset:
Ultra-Precise Clock Synchronization via Distant Entanglement (2005)

Abstract : We have demonstrated a spectrally bright source of entangled photon pairs that are necessary for transferring entanglement from photons to a pair of atoms at significant distance. We have shown how a measurement of the degree of entanglement may be used to deduce the relative speed between two frames, without direct measurement of velocities.
The Mitochondrial Genome of the Venomous Cone Snail Conus consors (2012)

Cone snails are venomous predatory marine neogastropods that belong to the species-rich superfamily of the Conoidea. So far, the mitochondrial genomes of two cone snail species (Conus textile and Conus borgesi) have been described, and these feed on snails and worms, respectively. Here, we report the mitochondrial genome sequence of the fish-hunting cone snail Conus consors and describe a novel putative control region (CR) which seems to be absent in the mitochondrial DNA (mtDNA) of other cone snail species. This possible CR spans about 700 base pairs (bp) and is located between the genes encoding the transfer RNA for phenylalanine (tRNA-Phe, trnF) and cytochrome c oxidase subunit III (cox3). The novel putative CR contains several sequence motifs that suggest a role in mitochondrial replication and transcription.
Lipid/Peptide/Nucleotide Separation with MALDI-Ion Mobility-TOF MS (2004)

Matrix-assisted laser desorption/ionization when combined with ion mobility-orthogonal time-of-flight mass spectrometry is a viable technique for fast separation and analysis of biomolecules in complex mixtures. Isobaric lipid, peptide, and oligonucleotide ions are preseparated before mass analysis by differences of up to 30% in mobility drift time. Ions of similar chemical type fall along well-defined "trend lines" (with deviations of approximately 3%) when plotted in two-dimensional representations of ion mobility as a function of m/z. Discussion of fundamental and technical limitations of the technique point to its potential for being most useful when applied to systems such as bodily fluids and intact tissue, where an alternative chemical or chromatographic preseparation step prior to mass analysis is either impractical or undesirable.
FINCHSCOPE: Motionless Fluorescence Digital Holographic Microscopy (2008)

We show new 3-D fluorescence holographic microscopes which are fast, simple, immune to vibration, since the interference occurs in a single beam path, and achieve high resolution 3-D microscopic images using high numerical aperture objectives. Article not available.
Positive Tone, Chemically Amplified, Cross-Linkable Dielectric (2013)

Abstract not Available.
The Effect of Protein Environment on Photoexcitation Properties of Retinal (2011)

Retinal is the photon absorbing chromophore of rhodopsin and other visual pigments, enabling the vertebrate vision process. The effects of the protein environment on the primary photoexcitation process of retinal were studied by time-dependent density functional theory (TDDFT) and the algebraic diagrammatic construction through second order (ADC(2)) combined with our recently introduced reduction of virtual space (RVS) approximation method. The calculations were performed on large full quantum chemical cluster models of the bluecone (BC) and rhodopsin (Rh) pigments with 165-171 atoms. Absorption wavelengths of 441 and 491 nm were obtained at the B3LYP level of theory for the respective models, which agree well with the experimental values of 414 and 498 nm. Electrostatic rather than structural strain effects were shown to dominate the spectral tuning properties of the surrounding protein. The Schiff base retinal and a neighboring Glu-113 residue were found to have comparable proton affinities in the ground state of the BC model, whereas in the excited state, the proton affinity of the Schiff base is 5.9 kcal/mol (0.26 eV) higher. For the ground and excited states of the Rh model, the proton affinity of the Schiff base is 3.2 kcal/mol (0.14 eV) and 7.9 kcal/mol (0.34 eV) higher than for Glu-113, respectively. The protein environment was found to enhance the bond length alternation (BLA) of the retinyl chain and blueshift the first absorption maxima of the protonated Schiff base in the BC and Rh models relative to the chromophore in the gas phase. The protein environment was also found to decrease the intensity of the second excited state, thus improving the quantum yield of the photoexcitation process. Relaxation of the BC model on the excited state potential energy surface led to a vanishing BLA around the isomerization center of the conjugated retinyl chain, rendering the retinal accessible for cis-trans isomerization. The energy of the relaxed excited state was found to be 30 kcal/mol (1.3 eV) above the minimum ground state energy, and might be related to the transition state of the thermal activation process.
Transparent And Solution Processable Low Contact Resistance Swcnt/Azonp Bilayer Electrodes For Sol-Gel Metal Oxide Thin Film Transistor (2015)

The contact resistance between source/drain electrodes<br> and semiconductor layer is an important parameter affecting electron<br> transporting performance in the thin film transistor (TFT). In this<br> work, we introduced a transparent and the solution prossable<br> single-walled carbon nanotube (SWCNT)/Al-doped ZnO nano particle<br> (AZO NP) bilayer electrodes showing low contact resistance with<br> indium-oxide (In2O3) sol gel thin film. By inserting low work function<br> AZO NPs into the interface between the SWCNTs and the In2O3 which<br> has a high energy barrier, we could obtain an electrical Ohmic contact<br> between them. Finally, with the SWCNT-AZO NP bilayer electrodes,<br> we successfully fabricated a TFT showing a field effect mobility of<br> 5.38 cm2/V·s at 250°C.
Real‐Time DSP Fundamentals and Implementation Considerations (2006)

This chapter contains sections titled: Number Formats Used in the Blackfin Processor Dynamic Range, Precision, and Quantization Errors Overview of Real-Time Processing Introduction to the IIR Filter-Based Graphic Equalizer Design of IIR Filter-Based Graphic Equalizer Using Blackfin Simulator Design of IIR Filter-Based Graphic Equalizer with BF533/BF537 EZ-KIT Implementation of IIR Filter-Based Graphic Equalizer with LabVIEW Embedded Module for Blackfin Processors More Exercise Problems
TAPA-1, the Target of an Antiproliferative Antibody, Defines a New Family of Transmembrane Proteins (1990)

A murine monoclonal antibody was identified by its ability to induce a reversible antiproliferative effect on a human lymphoma cell line. Immunoprecipitation studies revealed that the antibody reacted with a 26-kilodalton cell surface protein (TAPA-1). A diverse group of human cell lines, including hematolymphoid, neuroectodermal, and mesenchymal cells, expressed the TAPA-1 protein. Many of the lymphoid cell lines, in particular those derived from large cell lymphomas, were susceptible to the antiproliferative effects of the antibody. TAPA-1 may therefore play an important role in the regulation of lymphoma cell growth. A cDNA clone coding for TAPA-1 was isolated by using the monoclonal antibody to screen an expression library in COS cells. Analysis of the deduced amino acid sequence indicated that the protein is highly hydrophobic and that it contains four putative transmembrane domains and a potential N-myristoylation site. TAPA-1 showed strong homology with the CD37 leukocyte antigen and with the ME491 melanoma-associated antigen, both of which have been implicated in the regulation of cell growth.
Mimetic Peptide to CDK Inhibitor p16 INK4a Induces Cell Death In Mantle Cell Lymphoma Cells: A New Strategy to Eradicate Minimal Residual Disease (2010)

Abstract Abstract 3921 Autologous stem cell transplantation (ASCT) is an effective treatment strategy for Mantle Cell Lymphoma (MCL) that has been shown to improve disease free survival. However, data from recent trials suggest that the presence of minimal residual disease (MRD) contributes to relapse following current intensive treatment strategies, including ASCT. Thus, we sought to test a highly selective approach to eradication of MRD in stem cell collections from MCL patients using targeted small peptides that disrupt the aberrant cyclin/CDKs interactions that are involved in the pathogenesis of MCL. In the current study, the efficacy of a mimetic peptide to the CDK inhibitor p16INK4a to eliminate MRD was tested. Using (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium) (MTS) cell viability assays, we demonstrated that a transducible TAT-p16 mimetic peptide was able to induce cell death in the MCL cell line, Jeko-1, in a dose and time-dependent fashion (see Figure). A TAT-p16 mimetic was able to induce cell death in approximately 60% of Jeko-1 cells after 4 hours of incubation, and approximately 80% of Jeko-1 cells at 24 hours. In contrast, the same dose of TAT-p16 mimetic had no effect on cell survival when it was incubated with CD34+ rich apheresis samples from healthy donors. Furthermore, CFU-GM, BFU-E colony assays showed that there was no toxicity of the TAT-p16 mimetic when compared to untreated cells or cells treated with a control, scrambled TAT-p16 peptide. TAT-p16 mimetic did not impair erythroblast differentiation but induced mild apoptotic cell death in the erythroblast cells. The strategy was further tested using a CD34+ enriched apheresis sample collected from a patient with MCL with documented MRD who had been treated on a clinical trial of ASCT for MCL. Using Real-time quantitative PCR for IgH and BCL1 gene rearrangements, we demonstrated that the TAT-p16 mimetic was able to reduce MRD level by 40% compared with the scrambled TAT-p16 peptide. These data suggest that the use of a peptide-mimetic to p16 selectively and effectively can reduce MRD in MCL cells and in an apheresis (stem cell) sample from a patient with MCL. Treatment with the peptide allowed differentiation of CD34+ progenitor cells. A combinational approach using additional targeted cell cycle regulatory peptides that block p21CIP1/WAF1 and cyclin D2 is being explored to optimize the efficacy of this purging technique. Thus, this novel strategy may be an effective, selective and non-toxic method for eradication of MRD in MCL. Disclosures: No relevant conflicts of interest to declare.
Large Oblate Hemispheroidal Ruthenium Particles Supported on Calcium Amide as Efficient Catalysts for Ammonia Decomposition (2018)

Ammonia decomposition is an important technology for extracting hydrogen from ammonia toward the realization of a hydrogen economy. Herein, it is reported that large oblate hemispheroidal Ru particles on Ca(NH<sub>2</sub> )<sub>2</sub> function as efficient catalysts for ammonia decomposition. The turnover frequency of Ru/Ca(NH<sub>2</sub> )<sub>2</sub> increased by two orders of magnitude when the Ru particle size was increased from 1.5 to 8.4 nm. More than 90 % ammonia decomposition was achieved over Ru/Ca(NH<sub>2</sub> )<sub>2</sub> with large oblate hemispheroidal Ru particles at 360 °C, which is comparable to that of alkali-promoted Ru catalysts with small Ru particle sizes. XAFS analyses revealed that Ru particles are immobilized on Ca(NH<sub>2</sub> )<sub>2</sub> by Ru-N bonds formed at the metal/support interface, which lead to oblate hemispheroidal Ru particles. Such a strong metal-support interaction in Ru/Ca(NH<sub>2</sub> )<sub>2</sub> is also substantiated by DFT calculations. The high activity of Ru/Ca(NH<sub>2</sub> )<sub>2</sub> with large Ru particles primarily originates from the shape and appropriate size of the Ru particles with a high density of active sites rather than the electron-donating ability of Ca(NH<sub>2</sub> )<sub>2</sub> .
Determination of the Polarities of ZnO Thin Films on Polar and Nonpolar Substrates Using Scanning Nonlinear Dielectric Microscopy (2000)

Using scanning nonlinear dielectric microscopy (SNDM) which we developed, we determined the polarities of ZnO thin films on various substrates including polar materials. SNDM is a useful tool for investigating the anisotropy of polar materials by measuring the nonlinear dielectric constant, whose sign changes in accordance with the polarity of the specimen. In conventional methods based on detecting the piezoelectric and pyroelectric responses, it is very difficult to determine the polarities of thin films, particularly in the case of laying these films on the polar substrates, because the detected signals from thin films are very small and those from the substrates are large. Our SNDM method, however, enables us to determine the polarities of thin films on polar substrates easily. Using SNDM, the polarities of ZnO thin films on several kinds of polar and nonpolar substrates were determined. We also determined experimentally that ZnO thin films grew with a sign opposite to the substrate polarity and it was suggested that pyroelectric effects mainly governed the polarity of ZnO films.
P.142L: Late‐News Poster : Electron Injecting Material for OLEDs driven by Oxide TFTs: Amorphous C12A7 Electride (2013)

Abstract Transparent thin film of amorphous 12CaO·7Al 2 O 3 electride, sputter‐deposited at RT, having work function of 2.9 − 3.1 eV, was found to act as a good electron injection layer for OLED, and was adequate in combination with n‐channel IGZO‐TFTs.
Reversible Addition-Fragmentation Chain Transfer Polymerization of Vinyl Acetate in Bulk and Suspension Systems (2014)

Suspension and bulk polymerizations of vinyl acetate (VAc) are performed in several experimental conditions, using cyanomethyl methyl(phenyl) carbamodithioate as the chain transfer agent (CTA). The polymerization kinetics are monitored in batch for bulk polymerizations, showing an inhibitory period at the beginning of the reaction runs, despite the particular experimental conditions used. More accurate control over the molecular properties of the synthesized poly(vinyl acetate) (PVAc) is achieved when high concentrations of CTA are used. Similar experimental conditions are applied to prepare PVAc particles via suspension polymerization of VAc in the presence of small amounts of CTA. It is possible to produce spherical particles with a narrow particle size distribution and predominant spherical morphology. Although the reactions yield low control over the molecular weight properties, it is possible to use the synthesized particles as macro-CTAs and promote chain extension reactions to extend the chain length of the PVAc.
Quantum nanophotonic devices based on rare-earth-doped crystals (Conference Presentation) (2017)

Quantum light-matter interfaces that reversibly map the quantum state of photons onto the quantum states of atoms, are essential components in the quantum engineering toolbox with applications in quantum communication, computing, and quantum-enabled sensing. In this talk I present our progress towards developing on-chip quantum light-matter interfaces based on nanophotonic resonators fabricated in rare-earth-doped crystals known to exhibit the longest optical and spin coherence times in the solid state. We recently demonstrated coherent control of neodymium (Nd3+) ions coupled to yttrium orthosilicate Y2SiO5 (YSO) photonic crystal nano-beam resonator. The coupling of the Nd3+ 883 nm 4I9/2-4F3/2 transition to the nano-resonator results in a 40 fold enhancement of the transition rate (Purcell effect), and increased optical absorption (~80%) - adequate for realizing efficient optical quantum memories via cavity impedance matching. Optical coherence times T2 up to 100 μs with low spectral diffusion were measured for ions embedded in photonic crystals, which are comparable to those observed in unprocessed bulk samples. This indicates that the remarkable coherence properties of REIs are preserved during nanofabrication process. Multi-temporal mode photon storage using stimulated photon echo and atomic frequency comb (AFC) protocols were implemented in these nano-resonators. Our current technology can be readily transferred to Erbium (Er) doped YSO devices, therefore opening the possibility of efficient on-chip optical quantum memory at 1.5 μm telecom wavelength. Integration with superconducting qubits can lead to devices for reversible quantum conversion of optical photons to microwave photons.
High-Throughput Phenotypic Assay to Screen for Anthelmintic Activity on Haemonchus contortus (2021)

Parasitic worms cause very significant diseases in animals and humans worldwide, and their control is critical to enhance health, well-being and productivity. Due to widespread drug resistance in many parasitic worms of animals globally, there is a major, continuing demand for the discovery and development of anthelmintic drugs for use to control these worms. Here, we established a practical, cost-effective and semi-automated high throughput screening (HTS) assay, which relies on the measurement of motility of larvae of the barber's pole worm (<i>Haemonchus contortus</i>) using infrared light-interference. Using this assay, we screened 80,500 small molecules and achieved a hit rate of 0.05%. We identified three small molecules that reproducibly inhibited larval motility and/or development (IC<sub>50</sub> values of ~4 to 41 µM). Future work will critically assess the potential of selected hits as candidates for subsequent optimisation or repurposing against parasitic nematodes. This HTS assay has a major advantage over most previous assays in that it achieves a ≥ 10-times higher throughput (i.e., 10,000 compounds per week), and is thus suited to the screening of libraries of tens of thousands to hundreds of thousands of compounds for subsequent hit-to-lead optimisation or effective repurposing and development. The current assay should be adaptable to many socioeconomically important parasitic nematodes, including those that cause neglected tropical diseases (NTDs). This aspect is of relevance, given the goals of the World Health Organization (WHO) Roadmap for NTDs 2021-2030, to develop more effective drugs and drug combinations to improve patient outcomes and circumvent the ineffectiveness of some current anthelmintic drugs and possible drug resistance.
Joint Power Control and Rate Adaptation for Video Streaming in Wireless Networks With Time-Varying Interference (2015)

This paper considers a cross-layer optimization framework for video streaming in multinode wireless networks with a time-varying interference environment. We develop a distributed joint power control and rate adaptation framework that exploits the time diversity of the wireless channels, satisfies the hard delay constraints associated with video applications, and respects a certain fairness criterion among the nodes. The proposed framework performs power allocation at the physical/media access control layers to achieve a certain target signal-to-interference-plus-noise ratio, such that the difference between the arrival and the departure rates at the queues is very small, and performs video rate adaptation at the video coding layer (upper layer) according to the nodes' demanded video quality, their channel conditions, and a given fairness criterion. A main challenge here is that the adaptation of the video rate and the power control is not performed at the same time scale. We deal with this issue and model the power and rate variations of the nodes as linear stochastic dynamic equations and formulate a risk-sensitive control problem that captures the hard delay constraints of the video services and the fairness criterion for resource utilization. We provide an optimal solution for this control problem and illustrate the performance of our framework through simulations.
Influence of Exciton-Polaron Quenching Occurring at the Interface Mixing Zone on the Operational Lifetime of Solution-Processed OLED (2019)

Proceedings of the International Display Workshops Volume 26 (IDW '19),Influence of Exciton-Polaron Quenching Occurring at the Interface Mixing Zone on the Operational Lifetime of Solution-Processed OLED
Cancer immunotherapy targeting neoantigens (2015)

Neoantigens are antigens encoded by tumor-specific mutated genes. Studies in the past few years have suggested a key role for neoantigens in cancer immunotherapy. Here we review the discoveries of neoantigens in the past two decades and the current advances in neoantigen identification. We also discuss the potential benefits and obstacles to the development of effective cancer immunotherapies targeting neoantigens.
Midtrimester maternal serum inhibin A levels after multifetal pregnancy reduction (2007)

In multifetal reduction to twin pregnancies, the maternal serum levels of inhibin A decrease to the level of twin pregnancies during the second trimester. Therefore, inhibin A may be effectively used as a marker for Down syndrome screening in cases of twin pregnancy following multifetal reduction.
Magnetic Removal of Cesium Ions Using γ-Poly(glutamic acid)-Coated Magnetite Particles with the Enhanced Effect of Zeolite Supplementation (2013)

Abstract Magnetic removal of cesium ions (Cs) by γ-poly(glutamic acid)-coated magnetite particles (PGA-MPs) was investigated using a variety of waters. Cs was sufficiently removed from fresh water in a pH range from 7.0 to 9.0, with a removal efficiency of higher than 80% by using 5 wt % PGA-MPs, while that from artificial seawater was limited to 30%. Zeolite particles were employed as a supplementary adsorbent to adsorb Cs before the collection of zeolite with PGA-MPs. The addition of 1 wt % zeolite particles enhanced the recovery of Cs up to 97.7 ± 0.2% for fresh water and the amount of PGA-MPs required for the treatment was reduced to 0.2 wt %. Nevertheless, such improvement was not observed for artificial seawater treatment. The zeolite supplementation method performed sufficiently on the recovery of Cs in tap water and spring water, and their recoveries were both higher than 93% with R.S.D. of less than 1%. These results strongly suggest that the provided procedure can be practically applied to the removal of Cs from various inland waters.
Effect of Magnet Types on Performance of High-Speed Spoke Interior-Permanent-Magnet Machines Designed for Traction Applications (2014)

Interior permanent magnet (PM) machines are considered the state of the art for traction motors, particularly in light-duty hybrid and electrical vehicles. These motors usually use neodymium-iron-boron (NdFeB) PMs. These magnets include both light rare-earth materials such as neodymium (Nd) as well as heavy rare-earth materials such as dysprosium (Dy). The main purpose of Dy is to enhance the magnet coercivity to avoid demagnetization under both high temperatures as well as flux weakening. One of the key risks in terms of using these rare-earth magnets is the significant fluctuation/increase in their prices over the past few years. Applications that use large quantities of these magnets, such as traction motors and wind generators, are the most affected by these fluctuations. There has been an ongoing global effort to try to reduce or eliminate the use of rare-earth materials (particularly Dy which is the most expensive) without sacrificing too much performance. This paper will focus on advanced spoke designs targeting traction applications. The goal of this paper is to come up with new spoke designs using various grades of Dy-free magnets as well as ferrites targeting the same set of specifications. This paper will provide a detailed comparison between the various designs highlighting the key tradeoffs in terms of power density, efficiency, flux-weakening capability, and magnet susceptibility to demagnetization. Also, a prototype using ferrites has been built and tested, and the experimental results will be presented.