gebhart/patrepeval huggingface dataset:
Nanostructured Conductive Polymer Gels as a General Framework Material To Improve Electrochemical Performance of Cathode Materials in Li-Ion Batteries (2017)

Controlling architecture of electrode composites is of particular importance to optimize both electronic and ionic conduction within the entire electrode and improve the dispersion of active particles, thus achieving the best energy delivery from a battery. Electrodes based on conventional binder systems that consist of carbon additives and nonconductive binder polymers suffer from aggregation of particles and poor physical connections, leading to decreased effective electronic and ionic conductivities. Here we developed a three-dimensional (3D) nanostructured hybrid inorganic-gel framework electrode by in situ polymerization of conductive polymer gel onto commercial lithium iron phosphate particles. This framework electrode exhibits greatly improved rate and cyclic performance because the highly conductive and hierarchically porous network of the hybrid gel framework promotes both electronic and ionic transport. In addition, both inorganic and organic components are uniformly distributed within the electrode because the polymer coating prevents active particles from aggregation, enabling full access to each particle. The robust framework further provides mechanical strength to support active electrode materials and improves the long-term electrochemical stability. The multifunctional conductive gel framework can be generalized for other high-capacity inorganic electrode materials to enable high-performance lithium ion batteries.
Author response: A single, continuous metric to define tiered serum neutralization potency against HIV (2017)

To quantify serum or antibody activity against HIV-1, logistic regression of single-dilution neutralization outcomes can efficiently summarize neutralization potency and indicate which samples may lack sufficient statistical support, for high-throughput screening in large-scale vaccine trials.
Clinical Implications of the New Equation to Estimate Glomerular Filtration Rate (2021)

Recently, a new full-age spectrum equation was proposed by the European Kidney Function Consortium (EKFC) to overcome the difficulty of using multiple glomerular filtration rate (GFR) estimation equations and problems of implausible changes in GFR during the transition from adolescence to adulthood and address GFR overestimation in young adults and in the older adults. To verify the impact on patient classifications, we applied the new equation to data of 38,188 adult patients, comparing GFR estimation using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) and EKFC equations. As expected, our data indicate that a significant proportion of patients will be reclassified downward by the EKFC compared to the CKD-EPI equation with a particular reference between CKD stages 1-2 and 2-3 and age categories of 18-30 and ≥61 years, respectively. Clinicians should be aware that any replacement for the EKFC equation will entail a period of different results in estimated GFR during the transition from the previous to the new equation.
Psychoeducation for bipolar disorder and risk of recurrence and hospitalization – a within-individual analysis using registry data (2019)

The results suggest that psychoeducation for bipolar disorder reduces the risk of mood episodes and inpatient care also when implemented in routine clinical practice.
Feasibility Study of Developing Green ECC Using Iron Ore Tailings Powder as Cement Replacement (2012)

This paper reports the results of an initial attempt of using iron ore tailings (IOTs) to develop greener engineered cementitious composites (ECCs). ECC is a unique class of high-performance fiber-reinforced cementitious composites featuring high tensile ductility and durability. However, the high cement usage in ECC limits the material greenness and increases the material cost compared with normal concrete. In this paper, IOTs in powder form are used to partially replace cement to enhance the environmental sustainability of ECC. Mechanical properties and material greenness of ECC containing various proportions of IOTs are investigated. The newly developed versions of ECC in this paper, with a cement content of 117.2–350.2 kg/m3, exhibit a tensile ductility of 2.3–3.3%, tensile strength of 5.1–6.0 MPa, and compressive strength of 46–57 MPa at 28 days. The replacement of cement with IOTs results in 10–32% reduction in energy consumption and 29–63% reduction in carbon dioxide emissions in green ECC compared with typical ECC. Thus, the feasibility of producing greener ECC with significantly reduced environmental impact using IOTs, and maintaining the mechanical properties of typical ECC, is experimentally demonstrated in this paper.
Relationship between dibutyryl cyclic AMP and microtubule organization in contracting heart muscle cells. (1978)

Rhythmic and synchronous contractions of interconnecting myocyte cultures prepared from fetal rat hearts are arrested upon the addition of 0.2--2.0 mM N6, O2'-dibuturyladenosine 3':5'-cyclic monophosphate (Bt2cAMP). The contractions arrested by Bt2cAMP are restored either by diluting the Bt2cAMP from the media or by adding colchicine. While colchicine restores Bt2cAMP-arrested myocyte contractions at concentrations as low as 1.0 micron, the inactive isomer lumicolchicine shows no effect. Morphologically, Bt2cAMP treatment of myocyte cultures results in the appearance of numerous elongated cellular processes not present in control cultures. Ultrastructural examination indicates that in Bt2cAMP-treated cells the intracellular distribution of microtubules is altered such that these organelles appear to accumulate in parallel arrays. In cells not treated with Bt2cAMP, the microtubules appear randomly oriented, while in cells treated with only colchicine, intact microtubules are not observed. The relationship between microtubules an heart cell contraction is discussed.
Investigation of optical transitions in InAs/GaAs(Sb)/AlAsSb quantum dots using modulation spectroscopy (2014)

InAs quantum dots (QDs) were grown in an AlAs0.56Sb0.44/GaAs matrix in the unintentionally doped (uid) region of an In0.52Al0.48As solar cell, establishing a variety of optical transitions both into and out of the QDs. The ultimate goal is to demonstrate sequential absorption, where one photon is absorbed, promoting an electron from the valence band into the QD, and a second photon is absorbed in order to promote the trapped electron from a QD state into the host conduction band. In this study, we directly investigate the optical properties of the solar cell using photoreflectance and evaluate the possibility of sequential absorption by measuring spectral responsivity with broadband infrared illumination.
An Extreme Case of Basilar Invagination in Rheumatoid Arthritis of the Cervical Spine (2004)

CHARLES A. REITMAN, MD; MICHAEL H. HECGENESS, MD, PHD
Risks of Copper and Iron Toxicity during Aging in Humans (2009)

Copper and iron are essential but also toxic metals. Their essentiality is known, but their toxicity, except for the genetic overload diseases, Wilson's disease and hemochromatosis, is not so well known. Yet, their toxicities are so general in the population that they are a looming public health problem in diseases of aging and in the aging process itself. Both metals are transition elements, and their resulting redox properties have been used during evolution in the development of oxidative energy generation. But both contribute to the production of excess damaging oxidant radicals. Evolution has kept stores of copper and iron in excess during the reproductive years because they are so vital to life. But the oxidant damage from these excess stores of metals builds up as we age, and natural selection ceases to act after about age 50 since diseases after that do not contribute to reproductive fitness. Diseases of aging such as Alzheimer's disease, other neurodegenerative diseases, arteriosclerosis, diabetes mellitus, and others may all be contributed to by excess copper and iron. A very disturbing study has found that in the general population those in the highest fifth of copper intake, if they are also eating a relatively high fat diet, lose cognition at over three times the normal rate. Inorganic copper in drinking water and in supplements is handled differently than food copper and is therefore more toxic. Trace amounts of copper in drinking water, less than one-tenth of that allowed in human drinking water by the Environmental Protection Agency, greatly enhanced an Alzheimer's-like disease in an animal model. In the last part of this review, I will provide advice on how to lower risks from copper and iron toxicity.
Cell cycle dependence of retroviral transduction: An issue of overlapping time scales (1998)

Recombinant retroviruses are currently used as gene delivery vehicles for the purpose of gene therapy. It is generally believed that the efficiency of retroviral transduction depends on the cell cycle status of the target cells. However, it has been reported that this is not the case for the transduction of human and murine fibroblasts, in contrast to other cell types such as lymphocytes. The predictions of a mathematical model that we constructed, offer an explanation of this contradiction, based on the dynamics of the underlying processes of target cell growth and the intracellular decay of retroviral vectors. The model suggests that the utility of synchronization experiments, that are usually employed to study cell cycle specificity, is severely limited when the time scales of the above kinetic events are comparable to each other. The predictions of the model also suggest the use of retroviral vectors as cell cycle markers, as an alternative way to detect cell cycle dependence of retroviral transduction. This method obviates the need for cell synchronization and therefore, it does not perturb the cell cycle or interfere with the life cycle of retroviral vectors. Moreover, it does not depend on the intracellular stability of retroviral vectors. Our results show that in contrast to previously reported results, transduction of murine fibroblasts is cell cycle dependent, and they are consistent with the current notion that mitosis is the phase that confers transduction susceptibility.
New Noncovalent Inhibitors of Penicillin-Binding Proteins from Penicillin-Resistant Bacteria (2011)

We found new noncovalent inhibitors of PBPs which represent important starting points for development of more potent inhibitors of PBPs that can target penicillin-resistant bacteria.
Extending KrF to 100-nm imaging with high-NA- and chromeless phase lithography technology (2002)

In this paper the concept of chromeless phase lithography (CPL) is introduced and experimental results on an ASML PAS 5500/800 are presented. CPL is a single exposure technique and is capable of resolution enhancement on all device layers (bright and dark field masks). Line space structures through pitch are measured with cross section and have O.35jim depth of focus (DOF) at 10% exposure latitude without forbidden pitches. CPL experimental results for a k1 of 0.38 (½ pitch) are presented for three DRAM device layers, isolation brick wall, storage capacitor, and honeycomb contact. Each of these layers have a DOF of O.35jim at 10% exposure latitude. CPL experimental results are presented for a SRAM gate and contact with lOOnm feature size (k1=O.32) and have a DOF of O.35jim at 10% exposure latitude.
New Bio‐Based Furanic Materials Effectively Absorb Metals from Water and Exert Antimicrobial Activity (2020)

Development of sustainable bio-based materials for removal of toxic contaminants from water is a high priority goal. Novel bio-based binary and ternary copolymers with enhanced ion-exchange, adsorption and antibacterial properties were obtained by using plant biomass-derived diallyl esters of furandicarboxylic acid (FDCA) as crosslinking agents and easily available vinyl monomers. The synthesized copolymer materials showed higher sorption capacities for Ni<sup>II</sup> , Co<sup>II</sup> and Cu<sup>II</sup> compared to the commercial ion-exchange resins, and they maintained their high metal adsorption capacities for over 10 cycles of regeneration. The synthesized copolymer gels containing 1-5 wt % of the crosslinker showed excellent water absorption capacities. The synthesized copolymers with 1 % crosslinker content showed swelling ratios high enough to also act as moisture absorbents. Synthesized copolymers with crosslinker content of 10 wt % performed as contact-active antibacterials by inhibiting the growth of Gram-positive (S. aureus) and Gram-negative bacteria (E. coli, K. pneumonia) in suspension tests.
A randomized trial on pelvic lymph node dissection versus no lymph node dissection at radical prostatectomy: Report of a trial in progress. (2022)

TPS5116 Background: The therapeutic benefit of pelvic lymph node dissection (PLND) in the surgical treatment of localized prostate cancer remains unproven. In this trial we aim to evaluate whether PLND reduces biochemical recurrence rates in clinically localized prostate cancer patients. We are presenting our experience in accrual during our first year of implementing this trial at Memorial Sloan Kettering Cancer Center. Methods: Patients without evidence of positive or suspicious pelvic lymph nodes on pre-operative imaging, and without prior pelvic radiation for prostate cancer are eligible. Following informed consent prior to radical prostatectomy, patients are enrolled onto the trial and surgeons are randomized using a cluster randomization. Surgeons are randomized to perform a PLND vs. no PLND for a 3-month period. Since our trial began accruing in July 2020, we have enrolled 366 patients (51 high risk, 286 intermediate risk, and 29 low risk) out of 996 eligible patients (37%) through January 2022. We have enrolled 168 patients in the PLND arm and 198 patients in the no PLND arm. Table 1 shows the breakdown of patient consent status in each risk group, by randomization assignment. At this stage in the accrual, we do not see evidence of consenting bias among PLND vs. no PLND randomization and risk group. We conclude that a single-center cluster randomized trial can accrue large numbers of patients in a short period of time, allowing for large scale trials to be completed. Currently, our trial is on track to complete accrual within our 5-year goal. Clinical trial information: NCT01407263. [Table: see text]
TIBIAL FORCES MEASURED IN VIVO AFTER TOTAL KNEE ARTHROPLASTY (2008)

The knee is a complex joint that is difficult to model accurately. Although significant advances have been made in mathematical modeling, these have yet to be validated successfully in vivo. Direct measurement of knee forces should lead to a better understanding of the stresses seen in total knee arthroplasty. An instrumented knee prosthesis was developed to measure forces in vivo after total knee arthroplasty. An instrumented tibial prosthesis was implanted in an 80-year-old male weighing 66 kg. The prosthesis measured forces at the four corners of the tibial tray. The patient walked approximately 1.6million steps per year before surgery (ankle accelerometer measurements). Knee forces were measured postoperatively during passive and active knee flexion, rehabilitation, rising from a chair, standing, walking, and climbing stairs. The patient was walking with the help of a walker by postoperative day 3. Peak tibial forces were 1.2 times body weight (BW). By the sixth postoperative day the tibial forces during gait were 1.7 times BW. At six weeks the peak tibial forces during walking had risen to 2.4time BW. Stair climbing increased from 1.9 times BW on day 6 to 3.3 times BW at six weeks. This represents the first direct in vivo measurement of tibial forces. In vivo tibiofemoral force data will be used to develop better biomechanical knee models and in vitro wear tests and will be used to evaluate the effect of improvements in implant design and bearing surfaces, rehabilitation protocols, and orthotics. This should lead to refining surgical techniques and to enhancing prosthetic designs that will improve function, quality of life, and longevity of total knee arthroplasty. This information is vital given the current trend in the increase of older population groups that are at higher risk for chronic musculoskeletal disorders.
Elimination and Quantification of Oxidation Induced Interstitial Injection via Ge Implants (2017)

The presence of Silicon-Germanium (SiGe) alloys at the Si/SiO2 interface during oxidation is known to suppress the injection of silicon self-interstitials that normally accompanies silicon oxidation and lead to observed effects such as Oxidation Enhanced Diffusion (OED) and stacking fault growth. This study uses a layer of implantation induced dislocation loops to measure interstitial injection as a function of SiGe layer thickness. The loops were introduced by implanting phosphorus and thermal annealing, and Germanium was subsequently introduced via a second implant at 3 keV over a range of doses between 1.7 x1014 cm-2 and 1.4 x1015 cm-2. Results show that partial suppression of interstitial injection can be observed for sub-monolayer doses of germanium, and that more than three monolayers of SiGe are necessary to fully suppress interstitial injection below our detection limit during oxidation. They further show that low energy implantation of germanium opens up possibilities to eliminate or modulate injection of interstitials during thermal processing of future devices.
In Vivo Imaging of the Photoreceptor Mosaic in Retinal Dystrophies and Correlations with Visual Function (2006)

AO fundus imaging is a reliable technique for assessing and quantifying the changes in the photoreceptor layer as disease progresses. Furthermore, this technique can be useful in cases where visual function tests provide borderline or ambiguous results, as it allows visualization of individual photoreceptors.
Peristaltic micropump fabricated by depositing parylene directly on liquid (2009)

We fabricated a peristaltic micropump by depositing Parylene on liquid directly (PoLD method), and tested its pumping characteristics. The Parylene thin film deposited on liquid not only forms the membrane of the micropump, but also composes the whole structure of the microfluidic system. The pumping membrane can be deformed by electrostatic force. This deformation can create liquid flow. Our micropump can transfer liquid at the flow rate of 2.7 mulscr/min and generate a differential pressure of 41 Pa. On the other hand, this pump made a wrinkle when the voltage applied and it leaked liquid. We devised the shape of the channel and electrodes and enabled it to close tightly.
Top-down Fabrication and Enhanced Active Area Electronic Characteristics of Amorphous Oxide Nanoribbons for Flexible Electronics (2017)

Inorganic amorphous oxide semiconductor (AOS) materials such as amorphous InGaZnO (a-IGZO) possess mechanical flexibility and outstanding electrical properties, and have generated great interest for use in flexible and transparent electronic devices. In the past, however, AOS devices required higher activation energies, and hence higher processing temperatures, than organic ones to neutralize defects. It is well known that one-dimensional nanowires tend to have better carrier mobility and mechanical strength along with fewer defects than the corresponding two-dimensional films, but until now it has been difficult, costly, and impractical to fabricate such nanowires in proper alignments by either "bottom-up" growth techniques or by "top-down" e-beam lithography. Here we show a top-down, cost-effective, and scalable approach for the fabrication of parallel, laterally oriented AOS nanoribbons based on lift-off and nano-imprinting. High mobility (132 cm<sup>2</sup>/Vs), electrical stability, and transparency are obtained in a-IGZO nanoribbons, compared to the planar films of the same a-IGZO semiconductor.
Anisotropic relaxation behavior of InGaAs/GaAs selectively grown in narrow trenches on (001) Si substrates (2017)

Selective area growth of InGaAs inside highly confined trenches on a pre-patterned (001) Si substrate has the potential of achieving a high III-V crystal quality due to high aspect ratio trapping for improved device functionalities in Si microelectronics. If the trench width is in the range of the hetero-layer thickness, the relaxation mechanism of the mismatched III-V layer is no longer isotropic, which has a strong impact on the device fabrication and performance if not controlled well. The hetero-epitaxial nucleation of InxGa1-xAs on Si can be simplified by using a binary nucleation buffer such as GaAs. A pronounced anisotropy in strain release was observed for the growth of InxGa1-xAs on a fully relaxed GaAs buffer with a (001) surface inside 20 and 100 nm wide trenches, exploring the full composition range from GaAs to InAs. Perpendicular to the trench orientation (direction of high confinement), the strain release in InxGa1-xAs is very efficiently caused by elastic relaxation without defect formation, although a small compressive force is still induced by the trench side walls. In contrast, the strain release along the trenches is governed by plastic relaxation once the vertical film thickness has clearly exceeded the critical layer thickness. On the other hand, the monolithic deposition of mismatched InxGa1-xAs directly into a V-shaped trench bottom with {111} Si planes leads instantly to a pronounced nucleation of misfit dislocations along the {111} Si/III-V interfaces. In this case, elastic relaxation no longer plays a role as the strain release is ensured by plastic relaxation in both directions. Hence, using a ternary seed layer facilitates the integration of InxGa1-xAs covering the full composition range.
ROADM System for Space Division Multiplexing with Spatial Superchannels (2013)

A two-span SDM system includes the first ROADM supporting spatial superchannels and the first cladding-pumped multicore-EDFA directly spliced to multicore transmission fiber. For 6×40×128-Gb/s SDM-WDM-PDM-QPSK transmission, BER penalties are ≤1.6dB in Add, Drop, and Express paths.
Communication Orale : "Piles à combustible par procédés plasmas (Projet PCP)" (2008)

3ème Edition de Tremplin Recherche, Paris, 12 Février 2008
Data Parallel C++ (2020)

SYCL™ is a heterogeneous programming framework built on top of modern C++. Data Parallel C++, recently introduced as part of Intel's oneAPI project, is an implementation of SYCL. Data Parallel C++ (DPC++) is being developed as an open-source project on top of Clang and LLVM. It combines C++, SYCL, and new extensions to improve programmer productivity when writing highly performant code for heterogeneous architectures.
Supplementary Material from The First-in-class Anti-EGFR Antibody Mixture Sym004 Overcomes Cetuximab Resistance Mediated by EGFR Extracellular Domain Mutations in Colorectal Cancer (2023)

&lt;p&gt;Figure S1: EGFR mutants binding to CTX, Sym004, PNM Figure S2: Clonogenic assay in EGFR mutants with CTX, Sym004, PNM&lt;/p&gt;
Synthesis of metallic magnesium nanoparticles by sonoelectrochemistry (2008)

4 nm sized metallic magnesium particles were prepared by the sonoelectrochemical method.