gebhart/patrepeval huggingface dataset:
Surface-micromachining processes for electrostatic microactuator fabrication (2003)

Etch characteristics are discussed of three forms of hydrofluoric acid, used as the micromachining etchant for fabricating a rotary variable-capacitance micromotor structure from polycrystalline silicon (poly-Si) thin films. Low-pressure chemically vapor deposited SiO/sub 2/ (LPCVD LTO) is used to form the sacrificial layers and LPCVD Si/sub 3/N/sub 4/ is used as an electrical isolation layer for the micromachined structure. 7:1, NH/sub 4/F:HF buffered HF (BHF), 48 wt.% concentrated hydrofluoric acid (LHF), and HF vapor in air (VHF) are evaluated at 20 degrees C for etch rate and selectivity, and attack of four types of LPCVD poly-Si films; POCl/sub 3/-doped or undoped, with or without 1150 degrees C annealing. Both BHF and VHF are found to damage POCl/sub 3/-doped poly-Si films, possibly by attack of grain boundaries. VHF is found to be effective for micromachining suspended structures since it avoids deformation of microstructures due to surface tension effects during drying after wet etching with LHF or BHF.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
N-Halamine Copolymers for Use in Antimicrobial Paints (2011)

A series of copolymers containing units of a novel hydantoinylacrylamide and the sodium salt of 2-(acrylamido)-2-methylpropanesulfonic acid have been synthesized. The homopolymer of the hydantoinylacrylamide compound was insoluble in water, while the copolymers with the sulfonic acid sodium salt were water-dispersible/soluble, with the solution becoming completely transparent when the feed ratio for the copolymer contained 7 parts of the hydantoin moiety to 3 parts of the sodium sulfonate moiety. The polymers were added into a commercial water-based latex paint, and upon drying, the painted surfaces treated with the water-miscible copolymers were rendered antimicrobial following chlorination with dilute household bleach. The chlorinated homopolymer failed to provide an antimicrobial property for the paint because of its tendency to isolate into aggregates in the paint, while the completely miscible copolymers were capable of 6-log inactivation of Staphylococcus aureus and Escherichia coli O157:H7 within 5 min of contact time.
Biochemical analysis of two cell surface glycoprotein complexes, very common antigen 1 and very common antigen 2. Relationship to very late activation T cell antigens. (1987)

Two mouse monoclonal antibodies (mAb), AJ2 and J143, define two related human cell surface protein complexes, very common antigen 1 (VCA-1) and very common antigen 2 (VCA-2). In the present report, these complexes have been defined with respect to: (i) subunit arrangement; (ii) monoclonal antibody binding sites; (iii) carbohydrate content; (iv) homology to other cell surface protein complexes; and (v) possible functional roles. Analysis of the antigens from a human melanoma cell line, MeWo, reveals that VCA-1 is a noncovalently linked heterodimer of 170- and 140 (designated 1401)-kDa polypeptides. mAb AJ2 reacts with an epitope on the 1401-kDa polypeptide. VCA-2 is composed of the same 1401-kDa polypeptide as VCA-1 and another 170-kDa species; this 170-kDa species consists of a second distinct 140-kDa (designated 140(2)) and a 30-kDa polypeptide which are disulfide-bonded. Indirect evidence indicates that mAb J143 reacts with an epitope on this 170-kDa complex. Peptide mapping has shown that the complexes are members of a family of cell surface proteins that include antigens present on activated T cells (designated very late activation antigens). Since VCA-2 is found predominantly on the basal membrane of adherent cells and its expression increases 12-fold when HUT-102 lymphoblastoid cells are grown as an adherent cell culture, we suggest that VCA-2 plays a role in cellular adherence.
Rôles des sidérophores bactériens et de mammifères dans les interactions hôtes-pathogènes (2015)

Iron is an essential nutriment for almost all forms of life, from bacteria to humans. Despite its key role in living organisms, iron becomes toxic at high concentrations. In the body, to circumvent this toxicity, almost all the intracellular iron is bound to proteins (especially to ferritin, a protein able to bind up to 4000 atoms of iron) and a small proportion (0.2% to 3%) to low molecular weight ligands (less than 2 kDa) constituting a free iron pool able to ensure the traffic of intracellular iron. A number of small molecules (citrate, phosphate, phospholipid, polypeptide) able to chelate iron, with variable affinities, have been known for a long time. In 2010, two teams have identified new mammal endogen chelators able to bind iron with similar chemical properties as bacterial siderophores. Recently, a few publications emphasized that most of the free iron present in the body cells is indeed linked to these siderophores, which play a key role in infected-host protection mechanisms during bacterial infections, through iron homeostasis and oxidative stress regulation.
Spectroscopic assessment of the degree of .pi.-stabilization of unsaturation in ruthenium complex, RuH(X)CO(P-tert-Bu2Me)2 (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSpectroscopic assessment of the degree of .pi.-stabilization of unsaturation in ruthenium complex, RuH(X)CO(P-tert-Bu2Me)2Jason T. Poulton, Kirsten Folting, William E. Streib, and Kenneth G. CaultonCite this: Inorg. Chem. 1992, 31, 15, 3190–3191Publication Date (Print):July 1, 1992Publication History Published online1 May 2002Published inissue 1 July 1992https://pubs.acs.org/doi/10.1021/ic00041a004https://doi.org/10.1021/ic00041a004research-articleACS PublicationsRequest reuse permissionsArticle Views242Altmetric-Citations107LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Highly efficient and stable blue organic light-emitting diodes through the selective quenching of long-living triplet exciton of a thermally activated delayed fluorescence emitter (2021)

High efficiency and long lifetime were achieved in the thermally activated delayed fluorescent organic light-emitting diodes by selective quenching of long-living triplet excitons.
Surface Heating Fuser with Roller Structure (2014)

The surface heating fuser structure has low energy consumption and high heating speed due to its low heat capacity and simple structure. The authors have introduced a surface heating fuser system in NIP 29. The heating material is composed of carbon nano tube and silicon rubber composite, and fabricated with thin film layer structure in order to minimize the heat capacity. A nip supporting member is applied to the heating tube inside slide along the surface of heating tube. But the high friction between the nip support member and the heating tube caused to the limitation of fusing speed and failure of electrical supply unit due to leaked lubricant. In this study, the roller type surface heating fuser structure is proposed. The fusing performance has been predicted by numerical simulation and verified by fabricated proto sample. The high fusing speed and durability of structure is confirmed through the evaluation of fusing system.
Dependence of Wound-induced Respiration in Potato Slices on the Time-restricted Actinomycin-sensitive Biosynthesis of Phospholipid (1977)

Actinomycin D prevents the full development in a 24-hour period of both wound respiration and cyanide resistance only when given in the first 10 to 12 hours following the cutting of potato tuber (Solanum tuberosum var. Russet) slices. The capacity for choline incorporation into phosphatidylcholine increases with slice aging and is inhibited by actinomycin D in the same time-restricted way. The time-restricted effectiveness of actinomycin D applies to the cutting-elicited enhanced synthesis of three critical enzymes of phosphatidylcholine synthesis, namely phosphorylcholine-glyceride transferase, phosphorylcholine-cytidyl transferase, and phosphatidylphosphatase. By contrast, actinomycim D given at any time is without effect on the measurable levels after 24 hours of a selection of glycolytic and mitochondrial respiratory enzymes. Neither succinic dehydrogenase nor cytochrome oxidase activity increases with time in aging potato slices in the presence or absence of chloramphenicol. The foregoing observations emphasize the central role of phospholipid, and ultimately membrane biosynthesis, in the development of wound-induced respiration.
Surface acoustic wave generation in ZX-cut LiNbO3 superlattices using coplanar electrodes (2009)

We report on a configuration to generate surface acoustic waves (SAWs) in acoustic superlattices based on ZX-cut periodically poled lithium niobate. The coplanar electrode configuration allows inducing Rayleigh type SAWs with the elastic energy mainly concentrated in between the electrodes gap and under the crystal surface. With respect to standard interdigitated transducers using the same crystal orientation, the efficiency of the SAW generation in the proposed designs are similar, while, for the same grating period, the resonance frequency that can be achieved is two times larger.
Inferring Social Ties in Pervasive Networks: An On-Campus Comparative Study (2013)

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Study of two‐dimensional electron gas in AlGaN channel HEMTs with high crystalline quality (2010)

Abstract Epitaxial structures of AlGaN channel high electron mobility transistors (HEMTs) were grown on sapphire and AlN substrates. Reduction in the full width at half maximum of X‐ray rocking curve for (10‐12) peak of the AlGaN channel layer owing to the reduction of threading dislocation densities resulted in a sharp decrease in the sheet resistance of 2‐dimensional electron gas (2DEG). In the case of AlGaN channel HEMTs, it was found that improvement of the crystalline quality of AlGaN channel layers is essential to the reduction of the sheet resistance of 2DEG. The use of AlN substrates resulted in improved crystalline quality of the AlGaN layer and lower 2DEG resistance, suggesting the high potential of AlN substrates for AlGaN channel HEMTs (© 2010 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)
Elucidating the Mechanisms of Acidochromic Spiropyran-Merocyanine Interconversion (2007)

The thermal and photochemical processes associated with the acid-induced conversions of 6-nitroBIPS, SP-1, to form the protonated merocyanine (MC-OH+) were investigated via UV/vis spectrophotometric studies in acetone. It was found that the mechanism of trifluoroacetic acid (TFA)-induced ring-opening of the SP and the rate of MC-OH+ formation follows a general acid catalysis mechanism. In accord with this mechanism, the thermal growth of the acid-induced ring-opened form (MC-OH+) was retarded as the concentration of TFA in the medium was increased. The N-protonated SP, i.e., SP-NH+, is formed in a competing side-equilibrium process as an unreactive "sink", with the nitrogen lone-pair no longer available to drive the ring-opening process and resulting in the inverse rate dependence as a linear 1/kobs vs [HA] plot. Addition of a tertiary amine to MC-OH+ regenerated MC which underwent thermal ring closure to the SP, thus restoring its function as a molecular switch. NMR titration of SP samples showed a downfield shift of the N-substituent peak upon increasing the TFA concentration. However, a saturation behavior could not be observed with SP-1 up to 1 M acid, unlike the model compound, N,N-dimethylaniline (N,N-DMA), which indicates a base strength order of N,N-DMA > SP-1. Further, we have demonstrated that in solvent acetone, on acidification, the normal photo- and thermochromic behavior is reversed; now MC-OH+ is photochemically transformed into SP-H+, which undergoes thermal ring-opening to MC-OH+.
PRDX1 and MTH1 cooperate to prevent ROS-mediated inhibition of telomerase (2018)

Telomerase counteracts telomere shortening and cellular senescence in germ, stem, and cancer cells by adding repetitive DNA sequences to the ends of chromosomes. Telomeres are susceptible to damage by reactive oxygen species (ROS), but the consequences of oxidation of telomeres on telomere length and the mechanisms that protect from ROS-mediated telomere damage are not well understood. In particular, 8-oxoguanine nucleotides at 3' ends of telomeric substrates inhibit telomerase in vitro, whereas, at internal positions, they suppress G-quadruplex formation and were therefore proposed to promote telomerase activity. Here, we disrupt the peroxiredoxin 1 (<i>PRDX1</i>) and 7,8-dihydro-8-oxoguanine triphosphatase (<i>MTH1</i>) genes in cancer cells and demonstrate that PRDX1 and MTH1 cooperate to prevent accumulation of oxidized guanine in the genome. Concomitant disruption of <i>PRDX1</i> and <i>MTH1</i> leads to ROS concentration-dependent continuous shortening of telomeres, which is due to efficient inhibition of telomere extension by telomerase. Our results identify antioxidant systems that are required to protect telomeres from oxidation and are necessary to allow telomere maintenance by telomerase conferring immortality to cancer cells.
Semiconductor approaches for tunable metamaterials in the infrared (2016)

Abstract not provided.
Methylation of TMEM176A , a key ERK Signaling Regulator, is a Novel Synthetic Lethality Marker of ATM Inhibitors in Human Lung Cancer (2021)

<b>Aim:</b> The role of <i>TMEM176A</i> methylation in lung cancer and its therapeutic application remains unclear. <b>Materials and methods:</b> Nine lung cancer cell lines and 123 cases of cancer tissue samples were employed. <b>Results:</b><i>TMEM176A</i> was methylated in 53.66% of primary lung cancer. Restoration of <i>TMEM176A</i> expression induced cell apoptosis and G2/M phase arrest, and inhibited colony formation, cell proliferation, migration and invasion. <i>TMEM176A</i> suppressed H1299 cell xenograft growth in mice. Methylation of <i>TMEM176A</i> activated ERK signaling and sensitized H1299 and H23 cells to AZD0156, an ATM inhibitor. <b>Conclusion:</b> The expression of <i>TMEM176A</i> is regulated by promoter region methylation. Methylation of <i>TMEM176A</i> is a potential lung cancer diagnostic marker and a novel synthetic lethal therapeutic marker for AZD0156.
Improved Battery Parameter Estimation Method Considering Operating Scenarios for HEV/EV Applications (2016)

This paper presents an improved battery parameter estimation method based on typical operating scenarios in hybrid electric vehicles and pure electric vehicles. Compared with the conventional estimation methods, the proposed method takes both the constant-current charging and the dynamic driving scenarios into account, and two separate sets of model parameters are estimated through different parts of the pulse-rest test. The model parameters for the constant-charging scenario are estimated from the data in the pulse-charging periods, while the model parameters for the dynamic driving scenario are estimated from the data in the rest periods, and the length of the fitted dataset is determined by the spectrum analysis of the load current. In addition, the unsaturated phenomenon caused by the long-term resistor-capacitor (RC) network is analyzed, and the initial voltage expressions of the RC networks in the fitting functions are improved to ensure a higher model fidelity. Simulation and experiment results validated the feasibility of the developed estimation method.
Automated Labeling and Classification of Business Rules from Software Requirement Specifications (2022)

Business Rules (BRs) are a critical artifact in the requirements elicitation phase of the software development life cycle. Several taxonomies have been proposed for classification of BRs. In this paper, we utilize Ross's BR classification schema and present an approach to automatically label and classify BRs along this schema. Our approach uses Data Programming (DP) for generating labeled training data needed for training two deep learning-based models to classify the BRs. We obtained an average labeling accuracy of 0.73 for all the BR classes using DP. Upon evaluating the approach on industryspecific dataset, we obtained highest weighted F-score (0.69) with a Bi-LSTM with attention-based model.
Effects of Dzyaloshinskii-Moriya interaction on the spin transfer magnetization switching in magnetic tunnel junctions (2015)

Magnetic tunnel junction (MTJ) are at the center of the magnetic random access memories (MRAM) technology. Nowadays, the research and development efforts are focusing on perpendicularly magnetized layers in the MTJ, taking advantage of the anisotropy provided by spin-orbit coupling at the interfaces with heavy metals such as Pt or Ta [1]. Recently, interfaces between ferromagnetic and heavy metals are also studied in a more fundamental context, because an antisymmetric interaction might appear at the interface, namely an interfacial Dzyaloshinskii-Moriya interaction (DMI) [2]. We will present a micromagnetic study of the reversal of the free layer magnetization direction by spin transfer torque under different amplitudes of the DMI. In particular, we will evaluate the energy barrier E <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">b</inf> or equivalently the thermal stability Δ=E <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">b</inf> /(300k <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">B</inf> ) and the minimal current density necessary for switching J <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c0</inf> as a function of the DMI amplitude.
Prospects for using peptide bioregulators for prevention and treatment of age-associated diseases of the musculoskeletal system (review of experimental data) (2019)

Увеличение продолжительности жизни человека, наблюдаемое во всем мире, требует особого внимания к возрастным изменениям, которые влияют на качество жизни. Остеоартроз и остеопороз входят в список основных заболеваний, которые приводят к ухудшению здоровья, изменению образа жизни и в конечном итоге, к инвалидности. Несмотря на то, что современные методы, применяемые для лечения как остеоартроза, так и остеопороза достаточно широки, разработка новых препаратов для лечения этих заболеваний является весьма актуальной. Среди таких препаратов особое внимание привлекают пептидные биорегуляторы, которые обладают геропротекторным эффектом, а также оказывают профилактическое действие при различных патологических состояниях организма. Одним из таких средств является пептидный препарат Хондролюкс®, который может быть рекомендован для профилактики заболеваний, связанных с изменениями хрящевой и костной тканей. Musculoskeletal diseases are most common in the elderly. The associated physical pain and limited ability to move impair quality of life and lead to disability in older patients. Among musculoskeletal diseases, osteoarthritis and osteoporosis are the most common. Osteoarthritis is a disease associated with age-related changes in the cartilage tissue. Osteoporosis, primarily postmenopausal, is characterized by decreased bone density. The similarity of these diseases is due to the fact that they both develop over a long time and are characteristic of older people. With age, both bone and cartilage tissues tend to lose their structure due to deterioration of metabolic processes. Therefore, it is important to maintain the musculoskeletal system as long as possible and focus on prevention of osteoarthritis and osteoporosis. Treatment of such diseases is associated with substantial economic costs; therefore, development of new, efficient and safe methods, which would qualitatively change the structural and functional state of bone and cartilage tissues, is highly relevant. Experimental studies showed that a new peptide drug, Chondrolux®, can be recommended for prevention and treatment of diseases associated with degenerative and dystrophic changes in the cartilage and bone tissues.
DEVELOPMENT OF A CONSTRUCTION METHOD OF R/C COLUMN USING PRECAST CONCRETE SHELL (2001)

For rationalization of construction work, a new construction method for R/C column using a precast concrete shell was developed. By a new method of assembling tie-hoops and constructing inner forms, and using high fluidity concrete, four workers can construct two high quality cast-in-place precast concrete shells in a day. In the case of a high-rise building, when a unit construction method is adopted (unit consists of a precast concrete shell combined with column main reinforcement and beam reinforcement) installation expenses decrease with work efficiency increase, a 14〜25% reduction is possible over the conventional method in respect to the length of time for skeleton construction work, the number of mechanical joints for reinforcement is decreased by about 25%. This can reduce the cost for skeleton construction of 32-story building by about 3%.
Metamaterial frequency-selective superabsorber (2009)

Using transformation optics a frequency-selective superabsorber can be constructed that consists of an absorbing core material coated with a shell of isotropic double negative metamaterial. For a fixed volume its absorption cross section can be made arbitrarily large at one frequency. The double-negative shell serves to amplify the evanescent tail of the high-order cylindrical waves, which induces strong scattering and absorption. Our conclusion is supported by both analytical Mie theory and numerical finite-element simulation. Interesting applications of such a device are discussed.