gebhart/patrepeval huggingface dataset:
Control of Full-Scale Converter based Wind Power Plants for damping of low frequency system oscillations (2011)

Damping of low frequency power oscillations is one of essential aspects of maintaining power system stability. In literature can be found publications on damping capability of Doubly Fed Induction Generator based wind turbines. This paper extends discussion on Wind Power Plant damping capability to Full-Scale Converter based type. Moreover resemblance of such Wind Power Plant to modern FACTS devices is recognized and exploited. Paper discusses many aspect of damping controller design, including feedback signal selection and control effectiveness with respect to wind farm location. Analysis and design is based on modal analysis, therefore matching modeling approach for wind power plant is proposed. Finally, performance of Wind Power Plant damping control is compared to a regular power system stabilizer installed on a synchronous generator.
Enhanced Light Absorption in Fluorinated Ternary Small-Molecule Photovoltaics (2017)

Using small-molecule donor (SMD) semiconductors in organic photovoltaics (OPVs) has historically afforded lower power conversion efficiencies (PCEs) than their polymeric counterparts. The PCE difference is attributed to shorter conjugated backbones, resulting in reduced intermolecular interactions. Here, a new pair of SMDs is synthesized based on the diketopyrrolopyrrole–benzodithiophene–diketopyrrolopyrrole (BDT-DPP2) skeleton but having fluorinated and fluorine-free aromatic side-chain substituents. Ternary OPVs having varied ratios of the two SMDs with PC61BM as the acceptor exhibit tunable open-circuit voltages (Vocs) between 0.833 and 0.944 V due to a fluorination-induced shift in energy levels and the electronic “alloy” formed from the miscibility of the two SMDs. A 15% increase in PCE is observed at the optimal ternary SMD ratio, with the short-circuit current density (Jsc) significantly increased to 9.18 mA/cm2. The origin of Jsc enhancement is analyzed via charge generation, transport, and diffuse reflectance measurements, and is attributed to increased optical absorption arising from a maximum in film crystallinity at this SMD ratio, observed by grazing incidence wide-angle X-ray scattering.
Automatic generation of synthesis units by unit selection based on closed‐loop training (1999)

This paper proposes a method that automatically generates synthesis units from a speech corpus, so that the distortion due to the modifications of pitch period and duration in the synthesized speech is minimized. In the proposed method, a large number of speech segments extracted from the speech corpus are defined as candidates of the synthesis unit. The distortion in the synthetic speech is calculated by modifying the pitch period and duration of candidates and comparing them to natural speech. The speech segment which minimizes the sum of distortions of synthetic speech with various pitch patterns is selected and defined as the synthesis unit. The proposed method is called the closed-loop training method, since the distortion in the synthesized speech is evaluated, and the result is fed back to select the synthesis unit. The generation of the synthesis unit by closed-loop training can be applied to various synthesizers, regardless of the kind of synthesis unit or the scheme of the synthesizer. An experiment was performed using the proposed method, where the synthesis units were generated by the synthesizer based on PSOLA and it was shown that the quality of the synthesized speech was improved compared to the conventional method where distortion by prosodic modification is not considered. © 1999 Scripta Technica, Syst Comp Jpn, 30(9): 1–7, 1999
Dislocation-Free GaN Nanowires (2003)

Journal Article Dislocation-Free GaN Nanowires Get access J P Zhang, J P Zhang Materials Department, University of California, Santa Barbara, CA 93106 Search for other works by this author on: Oxford Academic Google Scholar Y Wu, Y Wu Search for other works by this author on: Oxford Academic Google Scholar G S Cheng, G S Cheng Chemistry Department, University of California, Santa Barbara, CA 93106 Search for other works by this author on: Oxford Academic Google Scholar M Moskovits, M Moskovits Chemistry Department, University of California, Santa Barbara, CA 93106 Search for other works by this author on: Oxford Academic Google Scholar J S Speck J S Speck Materials Department, University of California, Santa Barbara, CA 93106 Search for other works by this author on: Oxford Academic Google Scholar Microscopy and Microanalysis, Volume 9, Issue S02, 1 August 2003, Pages 342–343, https://doi.org/10.1017/S1431927603441718 Published: 19 July 2003
Advances and challenges in log analysis (2012)

Logs contain a wealth of information to help manage systems.
Giant, benign, mucinous cystadenoma of the ovary: case study and literature review. (1992)

Benign, mucinous cystadenomas account for 15 per cent of all ovarian neoplasms. Of these, the giant variant occurs rarely. A morbidly obese, 52-year-old, white woman was seen for acute abdominal pain and diagnosed using computerized tomography as having a giant, benign, mucinous cystadenoma. At laparotomy, 21-kg cystic mass attached to the right ovary was removed. Total abdominal hysterectomy and bilateral salpingo-oophorectomy were performed. In such patients, special consideration must be given to hemodynamic and ventilatory monitoring and intraoperative fluid management. Recognition and subsequent surgical management of this and other large abdominal masses can be optimized by thoughtful, preoperative evaluation and careful planning of the operative approach.
Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917 (2022)

Enteric microbial pathogens, including Escherichia coli, Shigella and Cryptosporidium species, take a particularly heavy toll in low-income countries and are highly associated with infant mortality. We describe here a means to display anti-infective agents on the surface of a probiotic bacterium. Because of their stability and versatility, VHHs, the variable domains of camelid heavy-chain-only antibodies, have potential as components of novel agents to treat or prevent enteric infectious disease. We isolated and characterized VHHs targeting several enteropathogenic E. coli (EPEC) virulence factors: flagellin (Fla), which is required for bacterial motility and promotes colonization; both intimin and the translocated intimin receptor (Tir), which together play key roles in attachment to enterocytes; and E. coli secreted protein A (EspA), an essential component of the type III secretion system (T3SS) that is required for virulence. Several VHHs that recognize Fla, intimin, or Tir blocked function in vitro. The probiotic strain E. coli Nissle 1917 (EcN) produces on the bacterial surface curli fibers, which are the major proteinaceous component of E. coli biofilms. A subset of Fla-, intimin-, or Tir-binding VHHs, as well as VHHs that recognize either a T3SS of another important bacterial pathogen (Shigella flexneri), a soluble bacterial toxin (Shiga toxin or Clostridioides difficile toxin TcdA), or a major surface antigen of an important eukaryotic pathogen (Cryptosporidium parvum) were fused to CsgA, the major curli fiber subunit. Scanning electron micrographs indicated CsgA-VHH fusions were assembled into curli fibers on the EcN surface, and Congo Red binding indicated that these recombinant curli fibers were produced at high levels. Ectopic production of these VHHs conferred on EcN the cognate binding activity and, in the case of anti-Shiga toxin, was neutralizing. Taken together, these results demonstrate the potential of the curli-based pathogen sequestration strategy described herein and contribute to the development of novel VHH-based gut therapeutics.
Enhancing Low-Temperature SOFC Performance and Durability via Surface Modification (2023)

The development of active cathodes is one of the most critical challenges to lowering the operating temperature for SOFCs. By modifying the cathode surface chemistry the activity and durability can be simultaneously enhanced on high-performing, low-temperature cathodes. This low-temperature modification using multi-valent cations activates the highly defected surface and maintains the nanoscale electrocatalysts by bypassing the high-temperature sintering procedure for SOFC fabrication. The modified cathode at 600 °C shows an order of magnitude reduction in impedance to only 0.05 Ωcm 2 with a peak power density of 1.1 W/cm 2 and increases stability over 2000 hours. The combination of in situ characterization, distribution of relaxation time analysis on impedance spectroscopy, and surface chemistry analysis reveals the importance of surface chemistry control on the gas-solid reaction activity and durability and provides the design principle for future solid oxide cells.
The long search for a serotype independent pneumococcal vaccine (2020)

<b>Introduction</b>: Serotype replacement - a consequence of polysaccharide vaccine use - will continue to drive the inclusion of new serotypes on conjugate vaccines, increasing production complexity and costs, and making an already expensive vaccine less accessible to developing countries, where prevalence is higher and resources available for health systems, scarcer. Serotype-independent formulations are a promising option, but so far they have not been successful in reducing colonization/transmission.<b>Areas covered</b>: Protein-based and whole-cell vaccine candidates studied in the past 30 years. Challenges for serotype-independent vaccine development and alternative approaches.<b>Expert opinion</b>: Clinical trials performed so far demonstrated the importance to establish more reliable animal models and better correlates of protection. Defining appropriate endpoints for clinical trials of serotype-independent vaccine candidates has been a challenge. Inhibition of colonization has been evaluated, but concern on the extent of bacterial elimination is still a matter of debate. Challenges on establishing representative sites for clinical trials, sample sizes and appropriate age groups are discussed. On a whole, although many challenges will have to be overcome, establishing protein-based antigens as serotype-independent vaccines is still the best alternative against the huge burden of pneumococcal diseases in the world.
Optical feedback stabilization of the intensity oscillations in ultrahigh-frequency passively modelocked monolithic quantum-well lasers (1993)

The effect of optical feedback on the stability of the modelocking frequency of monolithic, passively modelocked semiconductor lasers at approximately 50 GHz is investigated. Optical feedback leads to linewidth narrowing, frequency pulling, and multiple modes of the intensity modulations in modelocked lasers, reminiscent of similar effects on the optical frequency in conventional continuous wave (CW) lasers. The narrowest observed line has a full-width-at-half-maximum (FWHM) of 56 kHz, which represents close to two orders of magnitude reduction of the linewidth compared to the situation without feedback. The effects of the optical feedback vary periodically as the length of the feedback delay is varied, with a periodicity that roughly matches the mode-locking wavelength. This wavelength is on the order of millimeters, which makes the mechanical stability of the optical feedback loop relatively uncritical.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Metal-Templated Design: Enantioselective Hydrogen-Bond-Driven Catalysis Requiring Only Parts-per-Million Catalyst Loading (2016)

Based on a metal-templated approach using a rigid and globular structural scaffold in the form of a bis-cyclometalated octahedral iridium complex, an exceptionally active hydrogen-bond-mediated asymmetric catalyst was developed and its mode of action investigated by crystallography, NMR, computation, kinetic experiments, comparison with a rhodium congener, and reactions in the presence of competing H-bond donors and acceptors. Relying exclusively on weak forces, the enantioselective conjugate reduction of nitroalkenes can be executed at catalyst loadings as low as 0.004 mol% (40 ppm), representing turnover numbers of up to 20 250. A rate acceleration by the catalyst of 2.5 × 10(5) was determined. The origin of the catalysis is traced to an effective stabilization of developing charges in the transition state by carefully orchestrated hydrogen-bonding and van der Waals interactions between catalyst and substrates. This study demonstrates that the proficiency of asymmetric catalysis merely driven by hydrogen-bonding and van der Waals interactions can rival traditional activation through direct transition metal coordination of the substrate.
Wavefront Engineering: Realizing Efficient Terahertz Band Communications in 6G and Beyond (2023)

Terahertz (THz) band communications is envisioned as a key technology for future wireless standards. Substantial progress has been made in this field, with advances in hardware design, channel models, and signal processing. High-rate backhaul links operating at sub-THz frequencies have been experimentally demonstrated. However, there are inherent challenges in making the next great leap for adopting the THz band in widespread communication systems, such as cellular access and wireless local area networks. Primarily, such systems have to be both: (i) wideband, to maintain desired data rate and sensing resolution; and, more importantly, (ii) operate in the massive near field of the high-gain devices required to overcome the propagation losses. In this article, it is first explained why the state-of-the-art techniques from lower frequencies, including millimeter-wave, cannot be simply repurposed to realize THz band communication systems. Then, a vision of wavefront engineering is presented to address these shortfalls. Further, it is illustrated how novel implementations of specific wavefronts, such as Bessel beams and Airy beams, offer attractive advantages in creating THz links over state-of-the-art far-field beamforming and near-field beamfocusing techniques. The paper ends by discussing novel problems and challenges in this new and exciting research area. Index Terms - Terahertz Communications; 6G; Wavefront Engineering; Bessel beams; Near field; Orbital Angular Momentum
Comparison of longitudinal change in sST2 vs BNP to predict major adverse cardiovascular events in asymptomatic patients in the community (2020)

Biomarker-based preventative and monitoring strategies are increasingly used for risk stratification in cardiovascular (CV) disease. The aim of this study was to investigate the utility of longitudinal change in B-type natriuretic peptide (BNP) and sST2 concentrations for predicting incident major adverse CV events (MACE) (heart failure, myocardial infarction, arrhythmia, stroke/transient ischaemic attack and CV death) in asymptomatic community-based patients with risk factors but without prevalent MACE at enrolment. The study population consisted of 282 patients selected from the longitudinal STOP-HF study of asymptomatic patients with risk factors for development of MACE. Fifty-two of these patients developed a MACE. The study was run in two phases comprising of an initial investigative cohort (n = 195), and a subsequent 2:1 (No MACE: MACE) propensity matched verification cohort (n = 87). BNP and sST2 were quantified in all patients at two time points a median of 2.5 years apart. Results highlighted that longitudinal change in sST2 was a statistically significant predictor of incident MACE, (AUC 0.60). A one-unit increment in sST2 change from baseline to follow up corresponded to approximately 7.99% increase in the rate of one or more incident MACE, independent of the baseline or follow-up concentration. In contrast, longitudinal change value of BNP was not associated with MACE. In conclusion, longitudinal change in sST2 but not BNP was associated with incident MACE in asymptomatic, initially event-free patients in the community. Further work is required to evaluate the clinical utility of change in sST2 in risk prediction and event monitoring in this setting.
Technology: Kidneys–The Present of Dialysis (2004)

Dialysis, in its routine 3 x week manifestation, undoubtedly is life saving. The therapy is limited by a number of factors that persist despite the development of safe machines and highly efficient dialyzers. The turnover of known, and very likely, many unknown uremic toxins, is rapid so that 3 x week dialysis is accompanied by relatively high levels of these substances. Only the lower part of the range of molecular weights of those putative uremic toxins, which are small proteins, are removed by current therapies. For substances such as phosphorus, long dialysis is successful in removing the excess retained dietary phosphorus, perhaps the only proven uremic toxin. The difficulty of achieving a normal extracellular volume is probably a major factor in the progression and poor outcomes of cardiovascular disease despite the potential improvement with management of hyperlipidemia, inflammation, potential arrhythmias, and cardiac failure due to other pathogenetic mechanisms. New developments in understanding of Vitamin D metabolism, Ca receptor inhibitor drugs, and control of hyperphosphatemia may reduce the problems of kidney bone disease and the adverse cardiovascular effect of calcium phosphorus disposition. Dialysis more frequent than 3 x week is already routinely, if only infrequently, used to deal with the very large volume or overhydrated patient. However, daily dialysis--whether short or long-is now beginning as a therapy with a large randomized NIH trial in the offing. Currently, the net growth of dialysis is approximately 4% a year, but it would not be surprising if there were a gradual increase in growth rates as CKD patients live longer due to control of cardiac disease. Eventually, the treatment of early kidney disease should reduce the dialysis population, particularly if diabetes can be better controlled or even prevented. The dialysis aspect of nephrology as a profession for physicians, nurses, and technicians appears to be on a long course with increasing demand and the need for applying what is already known, while awaiting new technical developments. Wearable artificial kidneys, involving the application of technology and use of new materials, are currently being investigated. The presence of nephrologists during the actual dialysis treatment is certainly not as evident as it was in the past. Reimbursement methodology has ensured at least a minimum of documented visits by nephrologists or nurse practitioners to the dialysis patient during treatment. It is controversial as to the value of this, but evidence has been presented that certain outcomes, such as use of appropriate dialysis dose and blood chemistries, are improved by more frequent visits. The present is over.
Ion irradiation enhanced crystal nucleation in amorphous Si thin films (1990)

The nucleation kinetics of the amorphous-to-crystal transition of Si films under 1.5 MeV Xe+ irradiation have been investigated by means of in situ transmission electron microscopy in the temperature range T=500–580 °C. After an incubation period during which negligible nucleation occurs, a constant nucleation rate was observed in steady state, suggesting that homogeneous nucleation occurred. Compared to thermal crystallization, a significant enhancement in the nucleation rate during high-energy ion irradiation (five to seven orders of magnitude) was observed with an apparent activation energy of 3.9±0.75 eV.
Fear–avoidance beliefs associated with perceived psychological and social factors at work among patients with neck and back pain: a cross-sectional multicentre study (2013)

Perceived psychological and social factors at work were strongly associated with fear-avoidance beliefs about work in sick-listed neck and back patients. The demand for physical endurance, control, support, high reward, as well as overcommittment at work outweighed pain and added to the burden of emotional distress and disability regarding fear-avoidance beliefs.
Longitudinal study of Middle East Respiratory Syndrome coronavirus infection in dromedary camel herds in Saudi Arabia, 2014–2015 (2017)

Two herds of dromedary camels were longitudinally sampled with nasal and rectal swabs and serum, between September 2014 and May 2015, and the samples were tested for Middle East Respiratory Syndrome (MERS) coronavirus RNA and antibodies. Evidence of MERS-CoV infection was confirmed in one herd on the basis of detection of virus RNA in nasal swabs from three camels and significant increases in the antibody titers from three others. The three viruses were genetically identical, thus indicating introduction of a single virus into this herd. There was evidence of reinfection of camels that were previously seropositive, thus suggesting that prior infection does not provide complete immunity from reinfection, a finding that is relevant to camel vaccination strategies as a means to prevent zoonotic transmission.
Intracellular Calcium Mobilization in Response to the Activation of Human Wild-Type and Chimeric Gonadotropin Receptors (2002)

It is well established that LH action is mediated primarily by adenylate cyclase/cAMP. However, the role of inositol phosphate/calcium in LH signaling is less well established. We examined the effects of gonadotropins in primary culture human granulosa-lutein cells and in HEK293 cells transiently transfected with human wild-type or chimeric gonadotropin receptors. The intracellular free calcium concentration was measured using fura-2 microspectrofluorometric techniques. Human (h) LH (2-4 microg/ml) and CG (10 IU/ml) consistently evoked oscillatory calcium signals in HEK293 cells transfected with hLH receptor, whereas hFSH (2-4 microg/ml) failed to elicit any response. Conversely, both hLH and hFSH failed to elicit a calcium response from HEK293 cells transfected with hFSHR, indicating the specificity of the response to the LH receptor. Pretreatment of transfected HEK293 cells with pertussis toxin (100 ng/ml) attenuated all gonadotropin-evoked calcium mobilization. Studies with chimeric LH receptor showed that the sequence of the long extracellular portion of the receptor was not critical for stimulation of PLC activity, but maintained agonist binding specificity. The C-terminal sequence of the receptor was clearly important for the generation of the basal calcium oscillations, but the precise extent of the critical sequence has yet to be identified. Although various subdivisions of this region were capable of stimulating calcium transients, an intact carboxyl-terminal third of the receptor was required for normal and sustained intracellular calcium signaling. Our study unequivocally shows that the hLH receptor is coupled to the inositol phosphate/calcium signaling pathway via a pertussis toxin-sensitive G protein-coupled receptor.
Longitudinal mode control in few-mode erbium-doped fiber lasers (1996)

We report an approach to the control of the longitudinal mode structure in erbium-doped fiber lasers that uses saturable absorbers and the spatial hole-burning effect in the laser cavity. Two- and three-mode fiber lasers are successfully demonstrated, and the laser output properties are compared with theoretical calculations.