gebhart/patrepeval huggingface dataset:
On-line monitoring technique of the refractive-index profile in the VAD process (1983)

A nondestructive on-line monitoring method to estimate the refractive-index profile in vapor-phase axial deposition (VAD) processing has been developed. This technique is developed on the basis of the deposition properties of a SiO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> -GeO <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> glass particles in the flame hydrolysis reaction. The profile monitoring accuracy is <tex xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">\pm 7 \times 10^{-5}</tex> in refractive-index difference. The estimated profiles during the porous preform fabrication are well coincided with those of the consolidated preform. The average bandwidth properties of graded-index fibers produced by adjusting the fabrication conditions, to be optimized with using present method, is 2.5 GHz . km <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.9</sup> at 1.3-μm wavelength.
Tuberoside M, a new cytotoxic spirostanol saponin from the seeds of Allium tuberosum (2002)

Tuberoside M (1), isolated from the seeds of Allium tuberosum, shows a significant inhibitory effect on the growth of the human promyelocytic leukemia cell line (HL-60) with IC50 value of 6.8 microg/ml. On the basis of spectral data and chemical reaction, its structure was established as (25S)-5beta-spirostane-1beta,3beta-diol 3-O-alpha-L-rhamnopyranosyl-(1-->4)-beta-D-glucopyranoside.
Performance of Joint XR and Best Effort eMBB Traffic in 5G-Advanced Networks (2023)

In this paper, we address the joint performance of eXtended reality (XR) and best effort enhanced mobile broadband (eMBB) traffic for a 5G-Advanced system. Although XR users require stringent throughput and latency performance, operators do not lose significant additional network capacity when adding XR users to an eMBB dominated network. For instance, adding an XR service at 45 Mbps with 10 ms packet delay budget, yields close to a 45 Mbps drop in eMBB capacity. In an XR only network layer, we show how the capacity in number of supported XR users depends significantly on the rate but also the latency budget. We show also how the XR service capacity is significantly reduced in the mixed service setting as the system goes into full load and other-cell interference becomes significant. The presented results can be used by cellular service providers to assess their networks performance of XR traffic based on their current eMBB performance, or as input to dimensioning to be able to serve certain XR traffic loads.
MEASUREMENT AND ANALYSIS OF A SPATIALLY SAMPLED BINAURAL ROOM IMPULSE RESPONSE DATASET (2014)

This paper presents a freely-available spatially-sampled binaural room impulse response dataset, measured at the University of Salford’s ITU-R BS.1116-compliant listening room. The Salford BBC Spatially-sampled Binaural Room Impulse Response dataset (SBSBRIR) was measured at a number of listening positions within the room. The dataset includes measurements of 12 loudspeakers, positioned at ear-height, using a head-and-torso simulator with a 2 ◦ head- az-imuth resolution and 15 different listener positions. The dataset can be used in the subjective and objective evaluation of domestic spatial audio reproduction. Measurement details, proce-dure and initial validation tests will be presented alongside the application of the dataset for future work. 1.
Effects of theTRPV1 antagonistABT‐102 on body temperature in healthy volunteers: pharmacokinetic/ pharmacodynamic analysis of three phase 1 trials (2012)

At exposures predicted to exert analgesic activity in humans, the effect of ABT-102 on body temperature is estimated to be 0.6 to 0.8°C. This effect attenuates within 2 to 3 days of dosing.
Chirp Spread Spectrum Signaling for Future Air-Ground Communications (2019)

In this paper, we investigate the use of chirp spread spectrum signaling over air-ground channels. This includes evaluation of not only the traditional linear chirp, but also of a new chirp signal format we have devised for multiple access applications. This new format is more practical than prior multi-user chirp systems in the literature, because we allow for imperfect synchronism. Specifically we evaluate multi-user chirp signaling over air-ground channels in a quasi-synchronous condition. The air-ground channels we employ are models based upon an extensive NASA measurement campaign. We show that our new signaling scheme outperforms the classic linear chirp in these air-ground settings.
ChemInform Abstract: Chemistry and Pharmacokinetics of Diarylthiophenes and Terphenyls as Selective COX‐2 Inhibitors. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
The H/sub 2/-norm of uncertain systems (2002)

This paper concerns the H/sub 2/-norm of plants with parametric uncertainty. For a set of continuous time plants, having denominators in intervals and numerators multiaffinely coupled to the dominators, we show that the largest H/sub 2/-norm occurs at a corner. In discrete time, corner results are presented for plants whose numerators are as above and whose denominators vary in certain structures for which stability corner results exist.
Synthesis and Stabilization of Silver Metallic Nanoparticles and Premetallic Intermediates in Perfluoropolyether/CO2 Reverse Micelle Systems (2003)

This article presents the stabilization of silver nanoparticle intermediates synthesized in ammonium perfluoropolyether (PFPE-NH4) reverse micelles with supercritical fluid (SCF) carbon dioxide solvent as the continuous phase. Specifically, the intermediates were formed by the reduction of silver nitrate salt (AgNO3) encapsulated within PFPE-NH4 reverse micelles. The effect of reducing agent type, reverse micelle water content, water core buffering, and bulk solvent type were all investigated as factors affecting stabilization of the silver nanoparticle intermediates. Particles were characterized by in situ UV−visible spectroscopy and transmission electron microscopy (TEM). The UV−vis spectrum of these nanosized silver particles is sensitive to particle size, and thus time-resolved spectral measurements were utilized as a means of monitoring both intermediate growth and persistence. The silver intermediates were stabilized in PFPE-NH4 reverse micelles as indicated by multiple UV−vis absorption bands that persist for periods of time measured to greater than 9 h. Intermediate stabilization is facilitated by a unique environment existing specifically as a result of PFPE-NH4 surfactant presence and its local water environment in the reverse micelle rather than any effects arising from the carbon dioxide solvent.
Learning $\textit{Ex Nihilo}$ (2019)

This paper introduces, philosophically and to a degree formally, the novel concept of learning $\textit{ex nihilo}$, intended (obviously) to be analogous to the concept of creation $\textit{ex nihilo}$. Learning $\textit{ex nihilo}$ is an agent's learning "from nothing," by the suitable employment of schemata for deductive and inductive reasoning. This reasoning must be in machine-verifiable accord with a formal proof/argument theory in a $\textit{cognitive calculus}$ (i.e., roughly, an intensional higher-order multi-operator quantified logic), and this reasoning is applied to percepts received by the agent, in the context of both some prior knowledge, and some prior and current interests. Learning $\textit{ex nihilo}$ is a challenge to contemporary forms of ML, indeed a severe one, but the challenge is offered in the spirt of seeking to stimulate attempts, on the part of non-logicist ML researchers and engineers, to collaborate with those in possession of learning-$\textit{ex nihilo}$ frameworks, and eventually attempts to integrate directly with such frameworks at the implementation level. Such integration will require, among other things, the symbiotic interoperation of state-of-the-art automated reasoners and high-expressivity planners, with statistical/connectionist ML technology.
Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck (2020)

The evolutionary mechanisms by which SARS-CoV-2 viruses adapt to mammalian hosts and, potentially, undergo antigenic evolution depend on the ways genetic variation is generated and selected within and between individual hosts. Using domestic cats as a model, we show that SARS-CoV-2 consensus sequences remain largely unchanged over time within hosts, while dynamic sub-consensus diversity reveals processes of genetic drift and weak purifying selection. We further identify a notable variant at amino acid position 655 in Spike (H655Y), which was previously shown to confer escape from human monoclonal antibodies. This variant arises rapidly and persists at intermediate frequencies in index cats. It also becomes fixed following transmission in two of three pairs. These dynamics suggest this site may be under positive selection in this system and illustrate how a variant can quickly arise and become fixed in parallel across multiple transmission pairs. Transmission of SARS-CoV-2 in cats involved a narrow bottleneck, with new infections founded by fewer than ten viruses. In RNA virus evolution, stochastic processes like narrow transmission bottlenecks and genetic drift typically act to constrain the overall pace of adaptive evolution. Our data suggest that here, positive selection in index cats followed by a narrow transmission bottleneck may have instead accelerated the fixation of S H655Y, a potentially beneficial SARS-CoV-2 variant. Overall, our study suggests species- and context-specific adaptations are likely to continue to emerge. This underscores the importance of continued genomic surveillance for new SARS-CoV-2 variants as well as heightened scrutiny for signatures of SARS-CoV-2 positive selection in humans and mammalian model systems.
Consensus Recommendations for the Use of Automated Insulin Delivery Technologies in Clinical Practice (2022)

The significant and growing global prevalence of diabetes continues to challenge people with diabetes (PwD), healthcare providers, and payers. While maintaining near-normal glucose levels has been shown to prevent or delay the progression of the long-term complications of diabetes, a significant proportion of PwD are not attaining their glycemic goals. During the past 6 years, we have seen tremendous advances in automated insulin delivery (AID) technologies. Numerous randomized controlled trials and real-world studies have shown that the use of AID systems is safe and effective in helping PwD achieve their long-term glycemic goals while reducing hypoglycemia risk. Thus, AID systems have recently become an integral part of diabetes management. However, recommendations for using AID systems in clinical settings have been lacking. Such guided recommendations are critical for AID success and acceptance. All clinicians working with PwD need to become familiar with the available systems in order to eliminate disparities in diabetes quality of care. This report provides much-needed guidance for clinicians who are interested in utilizing AIDs and presents a comprehensive listing of the evidence payers should consider when determining eligibility criteria for AID insurance coverage.
ChARM: NextG Spectrum Sharing Through Data-Driven Real-Time O-RAN Dynamic Control (2022)

Today's radio access networks (RANs) are monolithic entities which often operate statically on a given set of parameters for the entirety of their operations. To implement realistic and effective spectrum sharing policies, RANs will need to seamlessly and intelligently change their operational parameters. In stark contrast with existing paradigms, the new O-RAN architectures for 5G-and-beyond networks (NextG) separate the logic that controls the RAN from its hardware substrate, allowing unprecedented real-time fine-grained control of RAN components. In this context, we propose the Channel-Aware Reactive Mechanism (ChARM), a data-driven O-RAN-compliant framework that allows (i) sensing the spectrum to infer the presence of interference and (ii) reacting in real time by switching the distributed unit (DU) and radio unit (RU) operational parameters according to a specified spectrum access policy. ChARM is based on neural networks operating directly on unprocessed I/Q waveforms to determine the current spectrum context. ChARM does not require any modification to the existing 3GPP standards. It is designed to operate within the O-RAN specifications, and can be used in conjunction with other spectrum sharing mechanisms (e.g., LTE-U, LTE-LAA or MulteFire). We demonstrate the performance of ChARM in the context of spectrum sharing among LTE and Wi-Fi in unlicensed bands, where a controller operating over a RAN Intelligent Controller (RIC) senses the spectrum and switches cell frequency to avoid Wi-Fi. We develop a prototype of ChARM using srsRAN, and leverage the Colosseum channel emulator to collect a large-scale waveform dataset to train our neural networks with. Experimental results show that ChARM achieves accuracy of up to 96% on Colosseum and 85% on an over-the-air testbed, demonstrating the capacity of ChARM to exploit the considered spectrum channels.
Single cell detection using a microfluidic, passive, Fabry-Perot interferometer based biosensor (2005)

Polystyrene spheres, yeast cells, and blood cells in a microfluidic Fabry-Perot cavity constructed using thermocompressive gold bonding show unique transmission spectra that can be used for differentiation and are approximately consistent with modeling results.
Distinguishing Local and non-Local Demagnetization in Ferromagnetic FePt Nanoparticles (2019)

Time-resolved coherent X-ray diffraction is used to measure the spatially resolved magnetization structure within FePt nanoparticles during laser-induced ultrafast demagnetization. The momentum-dependent X-ray magnetic diffraction shows that demagnetization proceeds at different rates at different X-ray momentum transfer. We show that the observed momentum-dependent scattering has the signature of inhomogeneous demagnetization within the nanoparticles, with the demagnetization proceeding more rapidly at the boundary of the nanoparticle. A shell region of reduced magnetization forms and moves inwards at a supermagnonic velocity. Spin-transport calculations show that the shell formation is driven by superdiffusive spin flux mainly leaving the nanoparticle into the surrounding carbon. Quantifying this non-local contribution to the demagnetization allows us to separate it from the local demagnetization.
Modulation of the angiogenesis response through Ha‐ras control, placenta growth factor, and angiopoietin expression in mouse skin carcinogenesis (2003)

Tumor angiogenesis is governed by a complex balance of positive and negative angiogenic factors. Development of chemically-induced mouse skin tumors appears to be highly dependent on an early burst of neovascularization. We have previously shown that Ha-ras-driven vascular endothelial growth factor (VEGF) expression plays a pivotal role in this process. However, the status of other critical positive and negative angiogenic factors throughout skin tumorigenesis has not been studied to the same extent. In the present study, we show that another VEGF family member, placenta growth factor (PlGF), was highly upregulated at all tumor stages in a ras-dependent manner. The study of angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2), ligands of receptor tyrosine kinase 2 (Tie-2), showed that while stroma-derived Ang-2 was increased, epidermal Ang-1 expression was completely abolished at early papilloma formation. Studies using epidermal tumor cell lines suggest that the disappearance of Ang-1 also depends on ras activation, extending the plethora of events controlled by this oncogene in mouse skin carcinogenesis. Our results indicated that tumor development occurred in a strong angiogenesis-prone scenario in which PlGF and Ang-2 acted cooperatively with VEGF, whereas the negative or stabilizing effect of Ang-1 was abrogated. A time-course sequence of expression of angiogenic factors expressed throughout tumor growth, as well as the identification of key signaling molecules triggering the angiogenic response, may contribute to the development and testing of antiangiogenic therapeutic strategies with this in vivo tumor model.
Antiproliferative effects of interleukin-4 on freshly isolated non- Hodgkin malignant B-lymphoma cells (1992)

The pattern of in vitro growth response of freshly isolated non-Hodgkin malignant lymphoma B cells (NHML) to cytokines was investigated. Ten tumor specimens of low- or intermediate-grade malignancy were selected for study. To assess their proliferative capacity in vitro, B-lymphoma cells were activated through ligation of their surface Ig receptor with insolubilized anti-IgM antibodies or Staphylococcus aureus strain Cowan I (SAC). In the great majority of cases, interleukin-2 (IL-2) was the sole factor that significantly and reproducibly stimulated DNA synthesis in NHML activated through their surface Igs. Other B-cell tropic factors, including IL-4, IL-5, IL-6, and tumor necrosis factor-alpha (TNF-alpha), failed to elicit a growth response in most of the IL-2-responsive neoplastic samples. However, one specimen among 10 exhibited the opposite pattern of response and proliferated following culture with IL-4 and anti-Ig reagents, but not after IL-2 stimulation. Three specimens could also be induced for DNA synthesis on cross-linking of their surface Igs in the absence of exogenous growth factors. Although IL-4 could not support the in vitro growth of the majority of NHML cases, it strongly suppressed the proliferative signals delivered to these cells by anti-Ig reagents used alone or in combination with IL-2. Our data suggest that, in most cases, IL-4 essentially provides growth-inhibitory signals to NHML when they are activated through their surface Ig receptors and as such may be considered to be a valid candidate for future therapy of this type of mature B-cell malignancy.
A Low-Power Configurable Neural Recording System for Epileptic Seizure Detection (2013)

This paper describes a low-power configurable neural recording system capable of capturing and digitizing both neural action-potential (AP) and fast-ripple (FR) signals. It demonstrates the functionality of epileptic seizure detection through FR recording. This system features a fixed-gain, variable-bandwidth (BW) front-end circuit and a sigma-delta ADC with scalable bandwidth and power consumption. The ADC employs a 2nd-order single-bit sigma-delta modulator (SDM) followed by a low-power decimation filter. Direct impulse-response implementation of a sinc(3) filter and 8-cycle data pipelining in an IIR filter are proposed for the decimation filter design to improve the power and area efficiency. In measurements, the front end exhibits 39.6-dB DC gain, 0.8 Hz to 5.2 kHz of BW, 5.86- μVrms input-referred noise, and 2.4- μW power consumption in AP mode, while showing 38.5-dB DC gain, 250 to 486 Hz of BW, 2.48- μVrms noise, and 4.5- μW power consumption in FR mode. The noise efficiency factor (NEF) is 2.93 and 7.6 for the AP and FR modes, respectively. At 77-dB dynamic range (DR), the ADC has a peak SNR and SNDR of 75.9 dB and 67 dB, respectively, while consuming 2.75-mW power in AP mode. It achieves 78-dB DR, 76.2-dB peak SNR, 73.2-dB peak SNDR, and 588- μW power consumption in FR mode. Both analog and digital power supply voltages are 2.8 V. The chip is fabricated in a standard 0.6- μm CMOS process. The die size is 11.25 mm(2).
Design and operation of a fail-operational 5kW 800V-12V DC-DC converter (2019)

The spreading of autonomous drive systems is causing the increase of electrical power request on the 12V vehicle power net because, more and more on-board actuators are realized with electrical drives. Moreover, a very important requirement for autonomous drive systems is the capability of each component to operate also after a failure. A fail operational DC/DC power converter is therefore necessary to achieve the 12V power-net derived from the main battery of electric vehicles. In this paper a fail operational DC-DC 800 V/12 V, 5 kW power converter for automotive application is proposed. The converter topology is designed to ensure operability after a single failure. In this work, the sizing design procedure of each component of the converter is presented. Moreover, a numerical model of the converter is built and used to test the power converter both in normal and faulty conditions. Numerical simulation results validate the proposed topology showing both good dynamic performances and the required fail operational capabilities.
Catalytic Dimerization of Crotonates (2015)

A room-temperature dimerization of crotonates into 2-ethylidene-3-methylpentanedioates provides a sustainable route to difunctional monomers for step-growth polymerizations. We report two such dimerizations: (1) an organocatalytic dimerization using the N-heterocyclic carbene 1,3-diisopropyl-4,5-dimethylimidazol-2-ylidene (IiPr2Me2) and (2) a rapid dimerization (under 15 s to full conversion) using potassium t-butoxide in THF. In addition to unsaturated diesters, the resulting dimers can be easily converted to other step-growth monomers; namely, their corresponding diacids and saturated diesters.
Chiral Iron(II) and Cobalt(II) Complexes with Biphenyl‐Bridged Bis(pyridylimine) Ligands – Syntheses, Structures and Reactivities (2005)

Abstract A new class of iron( II ) and cobalt( II ) complexes with neutral, tetradentate bis(pyridylimine) chelate ligands bridged by a chiral 6,6′‐dimethylbiphenyl backbone has been synthesized. Their dihalogen derivatives gave spectral, magnetic and X‐ray diffraction results in agreement with a C 2 ‐symmetric, approximately octahedral geometry with cis ‐positioned halide ligands and high‐spin d‐electron configuration. 1 H NMR signals of these paramagnetic complexes were assigned by correlating line widths with reciprocal proton‐metal distances. Methyl substitution in 6‐position of the pyridyl rings lead to a different, presumably square‐pyramidal coordination geometry under dissociation of one chloride ion. Fe II dimethyl and diisocyanide derivatives were shown to have low‐spin configuration and C 1 ‐symmetric geometry. With respect to MAO‐activated olefin polymerization, significant catalytic activities were reproducibly obtained only under conditions, where the original complex structure was degraded. (© Wiley‐VCH Verlag GmbH &amp; Co. KGaA, 69451 Weinheim, Germany, 2005)