gebhart/patrepeval huggingface dataset:
Effects of Hydrogen Bonding on Nuclear Data Development of Liquid Anhydrous HF (2023)

Anhydrous Hydrogen Fluoride (HF) at high temperatures and pressures is used to process and manufacture nuclear fuel. As HF is often used directly with uranium, correct neutron thermal scattering cross sections are crucial to criticality safety applications. Classical molecular dynamics (CMD) simulation of the flexible HF system was used to create the thermal scattering law (TSL) and cross sections. The initial 2-site model is used in LAMMPS, and it can not capture the H-bond. To correctly represent the H-bond effects, a second, 3-site model was constructed in GROMACS. The 3-site model handled H-bonds by connecting a massless charge to the molecule. Key model parameters were compared to experimental data to verify the approach and models. To get the normalized VACF, the model was compared using hydrogen and fluorine bond length, density, potential energy, and diffusion coefficient. The phonon DOSs for both models were derived from the normalized VACF. DOSs were used to estimate the TSL (S(α,β)) and neutron thermal scattering cross sections for hydrogen in HF. The TSLs were evaluated using the FLASSH code with the Schofield diffusion model. It was observed that the representation of the hydrogen bonding changes the TSL's diffusional contributions. This is represented in the low energy scattering cross section, where intermolecular binding effects shift the cross section.
Evaluation of a rapid, multiphase MRE sequence in a heart‐simulating phantom (2009)

The aims of this study were to validate stiffness estimates of a phantom undergoing cyclic deformation obtained using a multiphase magnetic resonance elastography (MRE) imaging sequence by comparison with those obtained using a single-phase MRE sequence and to quantify the stability of the multiphase-derived stiffness estimates as a function of deformation frequency and imaging parameters. A spherical rubber shell of 10 cm diameter and 1 cm thickness was connected to a computerized flow pump to produce cyclic pressure variations within the phantom. The phantom was imaged at cyclic pressures between 18-72 bpm using single-phase and multiphase MRE acquisitions. The shear stiffness of the phantom was resolved using a spherical shell wave inversion algorithm. Shear stiffness was averaged over the slice of interest and plotted against pressure within the phantom. A linear correlation was observed between stiffness and pressure. Good correlation (R(2) = 0.98) was observed between the stiffness estimates obtained using the standard single-phase and the multiphase pulse sequences. Stiffness estimates obtained using multiphase MRE were stable when the fraction of the deformation period required for acquisition of a single image was not greater than 42%. The results demonstrate the potential of multiphase MRE technique for imaging dynamic organs, such as the heart.
Correlating Coating Quality of Coverage with Rheology for Mica-Based Paints (2020)

Abstract This paper examines the relationship between rheology and the qualitative appearance of dried, mica-based paint coatings used in the aerospace industry. The goal is to identify key rheological characteristics indicative of poor coating visual appearance, providing a screening tool to identify unsatisfactory paint formulations. Four mica paints were studied, having coating visual appearances ranging from very poor to very good. Strain sweeps indicated that the poor-quality paints have a smaller % strain midpoint in the linear visco-elastic range; while the good-quality paints have a lower G’/G” cross-over point in frequency sweeps. Thixotropy experiments utilizing single and multiple-loop hysteresis cycles plotting shear stress as a function of shear rate showed that the base mica paints with good appearance had nearly constant, reversible profiles in the forward and the backward directions; while the mica paints with poor appearance were irreversible with a noticeable gradual change in shear stress as more loops are run. The difference in area between the forward and the reverse curves was determined, leading to a quantifiable criterion that can differentiate good paints from poor paints with significance testing. This work would establish the first rheology model using hysteresis loops to predict the visual properties of mica-based paints.
1.3 µm InGaAsN vertical cavity surface emitting lasers grown by MOCVD (2002)

The first InGaAsN VCSELs grown by MOCVD with CW lasing wavelength longer than 1.3 µm are reported. The devices were of conventional pin structure with doped DBR mirrors. CW lasing up to 65°C was observed, with a maximum output power at room temperature of 0.8 mW for multimode devices and nearly 0.3 mW for singlemode devices.
Design and predictions for a high-altitude (low Reynolds-number) aerodynamic flight experiment (1999)

A sailplane being developed at NASA Dryden Flight Research Center will support a high-altitude flight experiment. The experiment will measure the performance parameters of an airfoil at high altitudes (70,000 to 100,000 ft), low Reynolds numbers (200,000 to 700,000), and high subsonic Mach numbers (0.5 and 0.65). The airfoil section lift and drag are determined from pitot and static pressure measurements. The locations of the separation bubble, Tollmien-Schlichting boundary layer instability frequencies, and vortex shedding are measured from a hot-film strip. The details of the planned flight experiment are presented. Several predictions of the airfoil performance are also presented. Mark Drela from the Massachusetts Institute of Technology designed the APEX-16 airfoil, using the MSES code. Two-dimensional Navier-Stokes analyses were performed by Mahidhar Tatineni and Xiaolin Zhong from the University of California, Los Angeles, and by the authors at NASA Dryden.
Abstract 955: Specific forms of mutant KRAS predict patient benefit from targeted therapy in the BATTLE-1 clinical trial in advanced non-small cell lung cancer (2011)

Abstract Mutant KRAS (mut-KRAS) is present in 17-25% of all human cancers, where it plays a critical role in driving cancer cell growth and resistance to therapy. Despite numerous attempts, there is still no effective therapy for mut-KRAS tumors. Understanding the signaling mechanisms activated by mut-KRAS and finding agents to inhibit mut-KRAS signaling are important unmet needs in cancer therapy today. The recently completed BATTLE-1 clinical trial, a prospective, multi-arm, biopsy-mandated, biomarker-driven, clinical trial in advanced refractory non-small cell lung cancer (NSCLC), found that mut-KRAS did not accurately predict patient outcome (progression-free survival) to targeted intervention. This finding contradicted published evidence for such a relationship from colon cancer and some previous NSCLC studies. We explored more specifically the nature of the KRAS mutations, which are primarily found at codons 12 and 13, where different base substitutions lead to alternate amino acid (aa) substitutions. NSCLC has a much higher proportion of mut-KRAS G12C(cysteine) aa substitutions (47%) due to carcinogens in tobacco smoke, and only 15% mut-KRAS have G12D(aspartate). These data contrast those in other solid tumors, such as colon or pancreas, which predominantly manifest mut-KRAS G12D (50%) and only 9% mut-KRAS G12C. In a subset analysis of the BATTLE-1 data, we showed significantly worse progression-free survival in patients with mut-KRAS G12C, versus other mut-KRAS including G12D (p=.041) and who were treated with erlotinib, vandetanib or sorafenib. In a panel of NSCLC cell lines with known mut-KRAS aa substitutions to identify pathways activated by the different mut-KRAS genotypes, we found that mut-KRAS G12D activates both PI-3-K and MEK signaling, while mut-KRAS G12C does not and alternatively activates PKCζ and RAL signaling. This finding was confirmed in immortalized human bronchial epithelial (HBEC) cells stably transfected with wt-KRAS or different forms of mut-KRAS. Our molecular modeling studies show that the different conformation imposed by mut-KRAS G12C could lead to altered association with downstream signaling transducers, compared to mut-KRAS G12D. The significance of the findings for developing mut-KRAS therapies is profound, since it suggests that not all mut-KRAS may be addictive; and that different combinations of inhibitors of downstream signaling may be needed for different mut-KRAS. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 955. doi:10.1158/1538-7445.AM2011-955
A CMOS imager using focal-plane pinhole effect for confocal multibeam scanning microscopy (2012)

A CMOS imager for confocal multi-beam scanning microscopy, where the pixel itself works as a pinhole, is proposed.
This CMOS imager is suitable for building compact, low-power, and confocal microscopes because the complex Nipkow
disk with a precisely aligned pinhole array can be omitted. The CMOS imager is composed of an array of sub-imagers,
and can detect multiple beams at the same time. To achieve a focal-plane pinhole effect, only one pixel in each subimager,
which is at the conjugate position of a light spot, accumulates the photocurrent, and the other pixels are unread.
This operation is achieved by 2-dimensional vertical and horizontal shift registers. The proposed CMOS imager for the
confocal multi-beam scanning microscope system was fabricated in 0.18-μm standard CMOS technology with a pinned
photodiode option. The total area of the chip is 5.0mm × 5.0mm. The number of effective pixels is 256(Horizontal) ×
256(Vertical). The pixel array consists of 32(H) × 32(V) sub-imagers each of which has 8(H) × 8(V) pixels. The pixel is
an ordinary 4-transistor active pixel sensor using a pinned photodiode and the pixel size is 7.5μm × 7.5μm with a fillfactor
of 45%. The basic operations such as normal image acquisition and selective pixel readout were experimentally
confirmed. The sensitivity and the pixel conversion gain were 25.9 ke-/lx•sec and 70 μV/e- respectively.
Binary classification of spoken words with passive elastic metastructures. (2021)

Many electronic devices spend most of their time waiting for a wake-up event: pacemakers waiting for an anomalous heartbeat, security systems on alert to detect an intruder, smartphones listening for the user to say a wake-up phrase. These devices continuously convert physical signals into electrical currents that are then analyzed on a digital computer -- leading to power consumption even when no event is taking place. Solving this problem requires the ability to passively distinguish relevant from irrelevant events (e.g. tell a wake-up phrase from a regular conversation). Here, we experimentally demonstrate an elastic metastructure, consisting of a network of coupled silicon resonators, that passively discriminates between pairs of spoken words -- solving the wake-up problem for scenarios where only two classes of events are possible. This passive speech recognition is demonstrated on a dataset from speakers with significant gender and accent diversity. The geometry of the metastructure is determined during the design process, in which the network of resonators ('mechanical neurones') learns to selectively respond to spoken words. Training is facilitated by a machine learning model that reduces the number of computationally expensive three-dimensional elastic wave simulations. By embedding event detection in the structural dynamics, mechanical neural networks thus enable novel classes of always-on smart devices with no standby power consumption.
Correction: Corrigendum: Visualization of Surface Acoustic Waves in Thin Liquid Films (2016)

Scientific Reports 6: Article number: 21980; Published online: 26 February 2016; Updated: 13 May 2016 This Article contains errors in the Results section under subheading ‘Measurement of anisotropy and focal point’, “The literature value41 for the SAW propagation velocity was fitted with a parabolicfunction 48 with the velocity v, the propagation angle ϕ towards the x direction and the anisotropy factor b.
Self-Supporting Nanocrystalline Diamond Foils – A New Concept for Crystalline Diamond on any Technical Surface (2010)

The manufacturing and application of self-supporting nanocrystalline diamond foils is introduced. The high temperature manufacturing of nanocrystalline diamond foils by hot-filament chemical vapour deposition (HFCVD) is separated from the low temperature application, allowing the coating of temperature sensitive materials, which cannot be coated by HFCVD conventionally. By coating appropriate template materials and stripping-off after the CVD-process, self-supporting, flexible nanocrystalline diamond foils with high hardness (&gt; 70 GPa) and very low thermal conductivity (&lt; 1 W/mK) with thicknesses of up to 100 µm can be produced. Lasercutting is an appropriate method for machining any desired geometry. Thus the possibility to use the extreme properties of diamond for protection against friction and wear on new substrate materials, e.g. steels, light metals and polymers, is generated.
Distinct signaling properties identify functionally different CD4 epitopes (1995)

The CD4 coreceptor interacts with non-polymorphic regions of major histocompatibility complex class II molecules on antigen-presenting cells and contributes to T cell activation. We have investigated the effect of CD4 triggering on T cell activating signals in a lymphoma model using monoclonal antibodies (mAb) which recognize different CD4 epitopes. We demonstrate that CD4 triggering delivers signals capable of activating the NF-AT transcription factor which is required for interleukin-2 gene expression. Whereas different anti-CD4 mAb or HIV-1 gp120 could all trigger activation of the protein tyrosine kinases p56lck and p59fyn and phosphorylation of the Shc adaptor protein, which mediates signals to Ras, they differed significantly in their ability to activate NF-AT. Lack of full activation of NF-AT could be correlated to a dramatically reduced capacity to induce calcium flux and could be complemented with a calcium ionophore. The results identify functionally distinct epitopes on the CD4 coreceptor involved in activation of the Ras/protein kinase C and calcium pathways.
Micro-Thermoelectric Hydrogen Sensor of Three Different Membrane Structures (2006)

We prepared micro-thermoelectric hydrogen sensors (micro-THSs) operating with a combination of the thermoelectric effect of SiGe thin film and Pt-catalyzed exothermic hydrogen oxidation of the catalyst. The membrane area of each sensor was heated by a micro heater. The responses of the micro-THSs with three different types of membranes to hydrogen in air were investigated. The micro-THS with a single membrane, which had a better thermal isolation than those of other membranes, reduced the power consumption of 251 mW and the time required to heat the membrane by 5 s. This micro-THS with a single membrane showed the optimal gas sensing property of voltage signal of 1.13 mV for 1% hydrogen in air with the low detection limit of 50 ppm.
Iron and Manganese Corroles Are Potent Catalysts for the Decomposition of Peroxynitrite (2006)

Katalytische Entgiftung: Eisen- und Mangancorrole zählen zu den effizientesten Katalysatoren für die Zersetzung von Peroxynitrit. Die Katalyserate des Eisenkomplexes ist höher als diejenige analoger Porphyrine, und mit dem Mangankomplex läuft eine Disproportionierung ab, deren Katalysezyklus abgebildet ist.
ChemInform Abstract: Synthesis of Novel Nucleic Acid Mimics via the Stereoselective Intermolecular Radical Coupling of 3′‐Iodo Nucleosides and Formaldoximes. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Air-ground channels &amp; models: Comprehensive review and considerations for unmanned aircraft systems (2012)

Use of unmanned aircraft systems (UASs) for multiple applications is expected to grow dramatically in the coming decades; this fact has motivated this paper's focus on fundamental physical layer characteristics relevant to UAS communications. In the past, for aeronautical communications with high transmitted power levels, narrow signal bandwidths, elevated ground site antennas in open areas, and low duty cycle transmissions, simple models for channel attenuation sufficed. In the future, when UAS ground stations may not all be in cleared areas with elevated antennas, higher data rates (wider bandwidths) are required, and small UASs with stringent power limitations still require high reliability, more comprehensive air-ground (AG) channel characteristics will be required in order to ensure robust signal designs for high-reliability AG links. We have found that no accurate, validated wideband models exist for the AG channel, particularly not in the Land C-bands that are being proposed for UASs. Airframe shadowing models also do not yet exist. We thus provide a comprehensive review of past work on the AG channel, and follow this with a brief description of plans for an AG channel measurement and modeling campaign. Resulting AG channel models will subsequently be used in the evaluation of candidate air interfaces for UAS control and non-payload communications (CNPC). The air interface must operate in the presence of both delay and Doppler spreads, and shadowing. It should also be spectrally efficient, low-latency, and reasonably robust to interference. We discuss these AG air interface considerations, and also show some initial modeling results based on both analysis and measurements.
High Precision Force Control by Multi-Sensor based Disturbance Observer (2006)

Motion control has been widely used in industry applications. One of the key technologies of motion control is a disturbance observer, which estimates a disturbance torque of a motion system and realizes a robust acceleration control. The disturbance observer can observe and suppress the disturbance torque within its bandwidth. Recent motion systems begin to spread in the society and they are required to have ability to contact with unknown environment. Such a haptic motion requires much wider bandwidth. However, since the conventional disturbance observer attains the acceleration information by the second order derivative of position response, the bandwidth is limited due to the derivative noise. This paper proposes a novel structure of a disturbance observer. An acceleration sensor is implemented to enlarge the bandwidth in the proposed multi-sensor based disturbance observer (MSDO). Thus, control performance of the MSDO is superior to the conventional one. In this paper, the MSDO is applied to force control and the viability of the proposed method is confirmed by fast Fourier transformation (FFT) analyses
Capacity Analysis of Downlink MIMO-OFDMA Resource Allocation with Resource Wise 1-bit Feedback (2009)

Opportunistic resource allocation in orthogonal frequency division multiple access (OFDMA) and multiple- input multiple-output (MIMO) techniques are among the key methods to achieve high spectral efficiency in future wireless communication networks. In this paper, we express information theoretical capacity results for MIMO OFDMA systems with optimal rate adaptation (ORA). Resource allocation is based on a resource block (RB)-wise one bit feedback method. The results indicate that the practical resource fair round robin allocation improves spectral efficiency with the suboptimal RB-wise one bit quantization. The analysis illustrate that space-time block coding (STBC) does not improve the allocation gain of a single antenna OFDMA scheme. The capacity analysis of antenna selection schemes illustrate the improvement of the performance compared to the single antenna transmission.
1P379 Expression and Purification of the Extracellular Region of Interleukin-13 Receptor α1 Chain and its Interaction with Ligand(15. Cellular signal transduction,Poster Session,Abstract,Meeting Program of EABS & BSJ 2006) (2006)

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PRESSURIZED SOLID OXIDE FUEL CELL/GAS TURBINE POWER SYSTEM (2000)

Power systems based on the simplest direct integration of a pressurized solid oxide fuel cell (SOFC) generator and a gas turbine (GT) are capable of converting natural gas fuel energy to electric power with efficiencies of approximately 60% (net AC/LHV), and more complex SOFC and gas turbine arrangements can be devised for achieving even higher efficiencies. The results of a project are discussed that focused on the development of a conceptual design for a pressurized SOFC/GT power system that was intended to generate 20 MWe with at least 70% efficiency. The power system operates baseloaded in a distributed-generation application. To achieve high efficiency, the system integrates an intercooled, recuperated, reheated gas turbine with two SOFC generator stages--one operating at high pressure, and generating power, as well as providing all heat needed by the high-pressure turbine, while the second SOFC generator operates at a lower pressure, generates power, and provides all heat for the low-pressure reheat turbine. The system cycle is described, major system components are sized, the system installed-cost is estimated, and the physical arrangement of system components is discussed. Estimates of system power output, efficiency, and emissions at the design point are also presented, and the system cost of electricity estimate is developed.
Brillouin penalty in Kerr-based nonlinear devices (2000)

Summary form only given. Recent work showed cross-phase modulation (XPM) has interesting features, almost unlimited speed of operation and wide operation bandwidth, for all-optical signal processing such as in nonlinear optical loop mirror-based wavelength conversion. Yet long fiber length requirement together with optical amplifiers needed to obtain suitable phase shift may affect the conversion process due to stimulated Brillouin scattering (SBS) on the drive signal. We demonstrated that high penalty in XPM-based nonlinear device arises from SBS effects when operating with a standard linewidth telecommunication laser.
Vaccinia virus injected human tumors: oncolytic virus efficiency predicted by antigen profiling analysis fitted boolean models (2019)

Virotherapy on the basis of oncolytic vaccinia virus (VACV) strains is a promising approach for cancer therapy. Recently, we showed that the oncolytic vaccinia virus GLV-1h68 has a therapeutic potential in treating human prostate and hepatocellular carcinomas in xenografted mice. In this study, we describe the use of dynamic boolean modeling for tumor growth prediction of vaccinia virus-injected human tumors. Antigen profiling data of vaccinia virus GLV-1h68-injected human xenografted mice were obtained, analyzed and used to calculate differences in the tumor growth signaling network by tumor type and gender. Our model combines networks for apoptosis, MAPK, p53, WNT, Hedgehog, the T-killer cell mediated cell death, Interferon and Interleukin signaling networks. The in silico findings conform very well with in vivo findings of tumor growth. Similar to a previously published analysis of vaccinia virus-injected canine tumors, we were able to confirm the suitability of our boolean modeling for prediction of human tumor growth after virus infection in the current study as well. In summary, these findings indicate that our boolean models could be a useful tool for testing of the efficacy of VACV-mediated cancer therapy already before its use in human patients.