gebhart/patrepeval huggingface dataset:
Repair of Peripheral Nerve Defects in Rabbits Using Keratin Hydrogel Scaffolds (2011)

Entubulation of transected nerves using bioabsorbable conduits is a promising alternative to sural nerve autografting, but full functional recovery is rarely achieved. Numerous studies have suggested that scaffold-based conduit fillers may promote axon regeneration, but no neuroinductive biomaterial filler has been identified. We previously showed that a nerve guide filled with keratin hydrogel actively stimulates regeneration in a mouse model, and results in functional outcomes superior to empty conduits at early time points. The goal of the present study was to develop a peripheral nerve defect model in a rabbit and assess the effectiveness of a keratin hydrogel filler. Although repairs with keratin-filled conduits were not as consistently successful as autograft overall, the use of keratin resulted in a significant improvement in conduction delay compared to both empty conduits and autograft, as well as a significant improvement in amplitude recovery compared to empty conduits when measurable regeneration did occur. Taking into account all study animals (i.e., regenerated and nonregenerated), histological assessment showed that keratin-treated nerves had significantly greater myelin thickness than empty conduits. These data support the findings of our earlier study and suggest that keratin hydrogel fillers have the potential to be used clinically to improve conduit repair.
FOURIER TRANSFORM SPECTROSCOPY WITHOUT MICHELSON INTERFEROMETER (2009)

Author Institution: Laboratoire de Photophysique Moleculaire, CNRS, Batiment 350, Universite Paris-Sud, 91405 Orsay cedex, France; Max Planck Institut fur Quantenoptik, Hans-Kopfermann-Str. 1, 85748 Garching, Germany
Effect of Inhibition of Gluconeogenesis on Ammonia Production in the Perfused Rat Kidney (1976)

1. Gluconeogenesis from lactate or from glutamine is inhibited by 90-100% by sodium quinolinate (1 mmol/l) or 3-mercaptopicolinate (150 nmol/l) in the perfused rat kidney. L-Tryptophan is not metabolized and is without effect. 2. Lactate uptake and glucose production are inhibited to the same degree by 3-mercaptopicolinate in the kidneys of well-fed or starved rats. 3. Inhibition of gluconeogenesis from glutamine (1 mmol/l) by 3-mercaptopicolinate is accompanied by 50% inhibition of ammonia production, and 34% inhibition of glutamine uptake, in the kidneys of acidotic rats. Ammonia production from glutamine was not inhibited in kidneys from non-acidotic rats. 4. It is concluded that the increased rate of gluconeogenesis from glutamine which occurs in acidotic rats is an essential and primary event regulating all of the increase in ammonia formation.
The prionoses and other conformational disorders (1998)

The basic pathogenesis of numerous neurodegenerative disorders is now thought to be related to abnormal protein conformation. The common theme in all these diseases is the conversion of a normal cellular and/or circulating protein into an insoluble, aggregated, beta-sheet rich form which is deposited in the brain, sometimes in the form of amyloid. These deposits are toxic and produce neuronal dysfunction and death. The most common of these illnesses is Alzheimer's disease (AD), in which a central event is the conversion of the normal soluble amyloid beta (sA beta) peptide to amyloid beta (A beta) within neuritic plaques and cerebral vessels. A unique category of the conformational conditions are prion related diseases (or prionoses), where the etiology is thought to be related to conversion of the normal prion protein, PrPC, into an infectious and pathogenic form, PrPSc. In the case of AD and the prionoses, the conformational change can be influenced by the presence of mutations in various gene products, as well as by chaperone proteins. Apolipoprotein E is thought to act as such a chaperone protein in AD; however, among the prionoses such a protein has been hypothesized to exist only by indirect evidence and is called "protein X". Our growing understanding of the mechanisms involved in this category of diseases, raises the possibility of therapeutic approaches based directly on the prevention and reversal of pathologic protein conformation.
HSPG2 (heparan sulfate proteoglycan 2) (2011)

Review on HSPG2 (heparan sulfate proteoglycan 2), with data on DNA, on the protein encoded, and where the gene is implicated.
Dissociation between left ventricular untwisting and filling. Accentuation by catecholamines. (1992)

Untwisting occurs principally during isovolumic relaxation before filling and is markedly enhanced in speed and magnitude by catecholamines. This partial return of the left ventricle to its preejection configuration before mitral valve opening could represent an important mechanism for the release of potential energy stored in elastic elements during the systolic deformation. These myocardial restoring forces would be markedly enhanced by physiological changes consequent to catecholamines such as during exercise, offsetting the concomitant shortening of the filling period.
ChemInform Abstract: The Oxidation of 2‐Oxazolines to 1,3‐Oxazoles. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Antibody to Surfactant Protein A Increases Sensitivity of Pulmonary Surfactant to Inactivation by Fibrinogen in Vivo (1996)

It has been suggested that surfactant protein-A (SP-A) protects surfactant activity from inhibitors such as fibrinogen. Substantial evidence indicates that inhibition of surfactant activity is often important in the pathogenesis of acute respiratory failure. Studies on surfactant function in the pulsating bubble surfactometer imply that SP-A helps to maintain low surface tension in the presence of inhibitors such as fibrinogen. We tested whether SP-A acts in this way in vivo. Rabbit pups, 29 d gestational age, were treated with a monoclonal antibody to rabbit SP-A (R5) followed by fibrinogen, or with control preparations (normal IgG and saline, respectively). Lung compliance was measured during ventilation throughout these experiments. Air-space volume and pulmonary edema were quantitated morphometrically. Animals receiving anti-SP-A antibody + fibrinogen showed substantial and significant impairment in lung compliance compared with control littermates receiving normal IgG and/or saline. Lungs from these animals showed decreased pulmonary air-space volume and increased alveolar edema. We conclude that SP-A protects pulmonary surfactant from inhibition by fibrinogen in vivo. This protective activity may be important in the pathogenesis of both adult and neonatal respiratory distress syndromes, and it may also be useful in devising therapies for these diseases.
Modular and Chemically Responsive Oligonucleotide “Bonds” in Nanoparticle Superlattices (2015)

Chemical bonds are a key determinant of the structure and properties of a material. Thus, rationally designing arbitrary materials requires complete control over the bond. While atomic bonding is dictated by the identity of the atoms, nanoparticle superlattice engineering, where nanoparticle "atoms" are held together by DNA "bonds", offers a route to design crystal lattices in a way that nature cannot: through altering the oligonucleotide bond. Herein, the use of RNA, as opposed to DNA, is explored by synthesizing superlattices in which nanoparticles are bonded by DNA/DNA, RNA/RNA, and DNA/RNA duplexes. By moving beyond nanoparticle superlattices assembled only with DNA, a new degree of freedom is introduced, providing programmed responsiveness to enzymes and greater bond versatility. Therefore, the oligonucleotide bond can have programmable function beyond dictating the structure of the material and moves nanoparticle superlattices closer to naturally occurring biomaterials, where the line between structural and functional elements is blurred.
A Robust Energy and Emissions Conscious Speed Control Framework for Connected Vehicles with Privacy Considerations (2020)

While perturbation schemes for vehicle-to-vehicle (V2V) communications can address data privacy concerns, they can significantly compromise the performance of the speed controllers of connected automated vehicles (CAVs) if such controllers rely on the preview information available through V2V in car-following scenarios. This paper presents a robust predictive speed controller for a CAV when preview information is provided through a privacy-guaranteed V2V communication network. This is the first such controller that considers energy and emissions concurrently. The impact of privacy assurance in the communication data is studied, while inter-vehicular distance constraint is guaranteed to be satisfied through a robust design of the predictive controller using a robust control invariant set. The robust optimal speed controller is shown to reduce fuel consumption and emissions successfully while satisfying the constraints even in the presence of perturbations in the V2V communication. Results suggest a need for an integrated design procedure to achieve the best performance under a given level of privacy guarantee and emissions requirements.
Challenges for Extending the Application of Nanoparticles in High Salinity Reservoirs (2016)

Abstract Nanoparticles, through many researches, has proven its capability to be an enhance oil recovery agent. In this study, we aim to investigate the performance of natural Zeolite in nanoscale on the recovery of crude oil compared to the normal water flooding method. The natural Zeolite nanoparticles are dispersed in seawater, however nanoparticles stability in saline water have been reported to be a challenge. Therefore and in order to investigate the performance of these natural Zeolite nanoparticles on oil recovery, we first stabilize them in seawater. Natural Zeolite nanoparticles of different concentrations (i.e. 0.02, 0.03, 0.05 wt%) were dispersed in seawater, where stability tests showed nanoparticles precipitations in less than an hour. This problem, of nanoparticles precipitation in seawater, was investigated by studying the performance of the Zeolite nanoparticles in each electrolyte that exits in seawater. The study results showed good stability of the Zeolite nanoparticles in NaCl solution that has a concentration of 0.14 wt%, however Zeolite nanoparticles will destabilize at higher concentrations of NaCl. Divalent salts that exist in seawater (i.e. MgCl2 and CaCl2) were also tested. The Zeolite nanoparticles were found to be destabilized even at very low concentrations of these salts. In the current work, we added surfactants to seawater to help in stabilizing the Zeolite nanoparticles. After initial screening of several surfactants, Polyvinylpyrrolidone (PVP) showed to be the best candidate to stabilize Zeolite nanoparticles in seawater. Experiments were then carried out using Zeolite nanoparticles plus (PVP) all dispersed in seawater. The effect of this dispersant on interfacial tension (IFT) was investigated where results revealed decrease in IFT values. The dispersant was shown also to change the wettability to more water wet condition which was due to the Zeolite nanoparticles, as a dispersant of only seawater and (PVP) was tested and found to not alter the wettability.
Truncating mutations in the Wilson disease gene ATP7B are associated with very low serum ceruloplasmin oxidase activity and an early onset of Wilson disease (2010)

In our German study cohort truncating ATP7B mutations were associated with lower ceruloplasmin serum oxidase levels and an earlier age of onset when compared to MMs. Measurement of serum ceruloplasmin oxidase might help to predict presence of truncating ATP7B mutations and might facilitate the mutation analysis.
Edge trapping mechanism of current collapse in III-N FETs (2005)

Simulations of GaN HFETs using the device simulator DESSIS show, in agreement with our experimental data, that enhanced trapping at both gate edges is responsible for the current collapse. These simulations also show a reduction of the collapse in DHFETs with an InGaN channel, in agreement with our gated transmission line measurements. The results demonstrate that hot electrons play an instrumental role in the collapse process.
Activationless Electron Self-Exchange of High-Valent Oxo and Imido Complexes of Chromium Corroles (2015)

Rate constants of electron self-exchange of high-valent oxo and imido complexes of chromium(V/IV) corrole have been determined in acetonitrile and toluene at various temperatures by electron paramagnetic resonance (EPR) line width variation of the EPR spectra. The observed activation enthalpies (ΔHobs(⧧)) of electron self-exchange of chromium(V)-oxo and -imido corrole with the corresponding chromium(IV) complexes are zero in toluene, whereas the ΔHobs(⧧) values are slightly positive in acetonitrile. Such activationless electron self-exchange transfer resulted in extremely fast electron-transfer reactions of chromium(V)-oxo and -imido corrole in sharp contrast with slow electron-transfer reactions of other high-valent metal-oxo and -imido complexes.
Phosphorylated 4E binding protein 1: A hallmark of cell signaling that correlates with survival in ovarian cancer (2006)

In patients with ovarian carcinoma, significant expression of p-4EBP1 was associated with high-grade tumors and a poor prognosis, regardless other oncogenic alterations upstream. This finding supports the study of this factor as a hallmark or pivotal factor in cell signaling in ovarian carcinoma that may crucial in the transmission of the proliferation cell signal and may reflect the real oncogenic role of this pathway in ovarian tumors.
Achieving proper exposure in surgical simulation. (2006)

One important technique common throughout surgery is achieving proper exposure of critical anatomic structures so that their shapes, which may vary somewhat among patients, can be confidently established and avoided. In this paper, we present an algorithm for determining which regions of selected structures are properly exposed in the context of a mastoidectomy simulation. Furthermore, our algorithm then finds and displays all other points along the surface of the structure that lie along a sufficiently short and straight path from an exposed portion such that their locations can be safely inferred. Finally, we present an algorithm for providing realistic visual cues about underlying structures with view-dependent shading of the bone.
Motion-compensated frame-rate up-conversion for H.264/AVC decoders (2005)

We propose a technique to perform frame-rate up-conversion in baseline H.264/AVC compliant decoders. It exploits a low-complexity motion estimation algorithm, including a novel method to enhance the consistency of motion fields. The final adaptive interpolation, through median filtering, provides excellent objective and subjective visual results.
Articular Cartilage: Evaluation with Fluid-suppressed 7.0-T Sodium MR Imaging in Subjects with and Subjects without Osteoarthritis (2013)

Quantitative sodium MR imaging at 7.0 T with fluid suppression by using adiabatic IR is a potential biomarker for osteoarthritis.
El Gamal Mix-Nets and Implementation of a Verifier. (2013)

A mix-net is a cryptographic protocol based on public key cryptography which enables untraceable communication through a collection of nodes. One important application is electronic voting where it enables the construction of systems which satisfies many voting security requirements, including verifiability of correct execution. Verificatum is an implementation of a mix-net by Douglas Wikström. This report concerns the implementation of a verifier and evaluation of the implementation manual for the Verificatum mix-net. The purpose of the document is to enable third parties to convince themselves that the mixnet has behaved correctly without revealing any secret information. This implementation is a simple version of the verifier using the document and some test vectors generated by the mix-net. The document contains all information but there are still some possibilities for further clarification in order to make it comprehensible to a larger audience.
A Test Structure for Statistical Evaluation of Characteristics Variability in a Very Large Number of MOSFETs (2009)

We have proposed and developed a test structure for evaluating electrical characteristics variability of a large number of MOSFETs in very short time using very simple circuit structure. The electrical characteristics such as threshold voltage, subthreshold swings S-factors, random telegraph signal noise, and so on, can be measured in over one million MOSFETs. This new test structure circuit and results measured by this circuit are very efficient in developing processes, process equipment and device structure which suppress variability.
Guerre chimique entre champignons: un arsenal de molécules bioactives (2010)

Des champignons du genre Fusarium sont de redoutables pathogenes pour les plantes et pour l’homme. Les infections qu’ils provoquent repondent mal aux traitements usuels. Dans une approche novatrice, la recherche envisage d’exploiter la guerre chimique que se livrent les champignons comme source de molecules antifongiques utilisables aussi bien en medecine qu’en agronomie. Soutenu par le Fond national suisse de la recherche scientifique (SNF), ce projet interdisciplinaire federe trois institutions de l’Arc lemanique: la station de recherche Agroscope Changins-Wadenswil ACW, le CHUV et l’Universite de Geneve. Stephanie Schurch1, Katia Gindro1, Olivier Schumpp1, Michel Monod2, Julie Verrier2, Nadine Bohni3 et Jean-Luc Wolfender3 1Station de recherche Agroscope Changins-Wadenswil ACW, 1260 Nyon 2Service de dermatologie et venereologie, Centre hospitalier universitaire vaudois CHUV, 1011 Lausanne 3Phytochimie et Produits Naturels Bioactifs, Ecole de Pharmacie Geneve-Lausanne, Universite de Geneve, Universite de Lausanne, 1211 Geneve Renseignements: Katia Gindro, e-mail: katia.gindro@acw.admin.ch, tel. +41 22 363 43 74 Guerre chimique entre champignons: un arsenal de molecules bioactives E c l a i r a g e
The Gordon Wilson Lecture: neurohormonal signaling pathways that link cardiac growth and death. (2007)

Far from being a simple muscular pump, the heart senses changes in hemodynamic forces and neurohormonal signaling, and responds by elaborating autocrine and paracrine factors that self-regulate cardiomyocyte contraction, growth, and programmed death. Interference with the afferent or efferent arms of this stress-response mechanism, as with inhibition of the beta-adrenergic or renin/angiotensin systems, is a mainstay of pharmacological therapy for heart failure. However, despite striking group-mean effects showing mortality benefits of neurohormonal antagonists, inter-individual variability in the therapeutic response to these agents suggests a pharmacogenomic interaction, where common sequence variations of genes that regulate neurohormonal signaling modify the individual response to treatment. Furthermore, there is increasing evidence that, depending upon physiological milieu, conventional neurohormone receptor-ligand pairs can activate non-traditional signaling pathways, with pathological consequences. Recently, studies that integrate the findings from human gene polymorphism discovery, recombinant gene variant expression in cell and animal models, and outcome or risk analysis of polymorphisms in human disease have provided additional understanding into adaptive and maladaptive events that are the consequence of the cardiac stress-response sequence.
Accuracy prediction for pedestrian detection (2017)

In this paper, we address the problem of predicting accuracy for pedestrian detection. We want to be able to predict the accuracy of a video analytic method without actually executing the method. We propose the use of texture descriptors and random forests to predict the accuracy of various pedestrian detection methods. Our experimental results demonstrate that using the local binary pattern (LBP) or a bank of Schmid and Gabor filters can capture spatial textural information associated with video quality degradation that can be used to predict accuracy. We also demonstrate how predicting the absolute accuracy can save network and computational resources.
Cellular base station antennas using microstrip antenna technology (1994)

A line of base station antenna products using microstrip technology has been developed for use in cellular communications. The antennas operate In the 800–900 MHz range. The main product is a half cylinder three beam radome enclosed antenna. There are three microstrip planar array panels within the half cylindrical radome. Each microstrip planar array panel illuminates one 60∗ sector and all three panels fit into the half cylindrical structure to provide RF coverage over 180°. An electro-mechanical down tilt actuator has also been designed into the structure to provide individual remote elevation adjustment to each panel. The antenna is in use in Bell Cellular's network today. Its aesthetics and performance improvements in operations and maintenance have proven to be a big advantage in densely populated urban and suburban areas. This paper describes the design, implementation and application of the antennas.
On Energy-efficiency in Wireless Networks: A Game-theoretic Approach to Cooperation Inspired by Evolutionary Biology (2014)

We develop a game-theoretic framework to investigate the effect of cooperation on the energy efficiency in wireless networks. We address two examples of network architectures, resembling ad-hoc network and network with central infrastructure node. Most present approaches address the issue of energy efficiency in communication networks by using complex algorithms to enforce cooperation in the network, followed by extensive signal processing at the network nodes. Instead, we address cooperative communication scenarios which are governed by simple, evolutionary-like, local rules, and do not require strategic complexity of the network nodes. The approach is motivated by recent results in evolutionary biology which suggest that cooperation can emerge in Nature by evolution, i. e. can be favoured by natural selection, if certain mechanism is at work. As result, we are able to show by experiments that cooperative behavior can indeed emerge and persist in wireless networks, even if the behavior of the individual nodes is driven by selfish decision making. The results from this work indicate that uncomplicated local rules, followed by simple fitness evaluation, can promote cooperation and generate network behavior which yields global energy efficiency in certain wireless networks.
A 56mW CT Quadrature Cascaded &#x003A3;&#x00394; Modulator with 77dB DR in a Near Zero-IF 20MHz Band (2007)

A 90nm CMOS CT quadrature ΣΔ modulator is designed for highly digitized wideband receivers. The ADC achieves 77dB DR and 20MHz BW around a 10.5MHz IF and is sampled at 340MHz. The cascaded modulator comprises programmable analog 2 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">nd</sup> -order quadrature filters and a digital quadrature noise-cancellation filter. The 0.5mm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> chip draws 56mW from a 1.2V supply