gebhart/patrepeval huggingface dataset:
Encapsulating Various Sulfur Allotropes within Graphene Nanocages for Long‐Lasting Lithium Storage (2018)

Abstract The encapsulation of sulfur within carbon matrices is widely utilized in the cathode of a rechargeable lithium–sulfur battery, whose energy density largely depends on the design of the carbon structure. Here, an advanced graphene nanocage structure with the capability of hosting both cyclo‐S 8 and smaller sulfur molecules (S 2–4 ) is reported. The cage inner cavity is partially filled with S 8 to form a yolk–shell structure that enables free volumetric variation of S 8 during (de)lithiation. In the graphene shell of the cage, S 8 are downsized to S 2–4 to activate extra sulfur loading sites within graphene layers. Importantly, the graphene shell exhibits inward volumetric variation upon (de)lithiation of the loaded S 2–4 , and the overall electrode strain is thus minimized. This prototyped design promises an ultimate solution to maximize sulfur loading in carbon matrices as well as to circumvent the polysulfide dissolution problem and boost the commercialization of lithium‐sulfur batteries in the future.
Molecular Basis for Recognition of Nucleoside Triphosphate by Gene 4 Helicase of Bacteriophage T7 (2010)

The translocation of DNA helicases on single-stranded DNA and the unwinding of double-stranded DNA are fueled by the hydrolysis of nucleoside triphosphates (NTP). Although most helicases use ATP in these processes, the DNA helicase encoded by gene 4 of bacteriophage T7 uses dTTP most efficiently. To identify the structural requirements of the NTP, we determined the efficiency of DNA unwinding by T7 helicase using a variety of NTPs and their analogs. The 5-methyl group of thymine was critical for the efficient unwinding of DNA, although the presence of a 3'-ribosyl hydroxyl group partially overcame this requirement. The NTP-binding pocket of the protein was examined by randomly substituting amino acids for several amino acid residues (Thr-320, Arg-504, Tyr-535, and Leu-542) that the crystal structure suggests interact with the nucleotide. Although positions 320 and 542 required aliphatic residues of the appropriate size, an aromatic side chain was necessary at position 535 to stabilize NTP for efficient unwinding. A basic side chain of residue 504 was essential to interact with the 4-carbonyl of the thymine base of dTTP. Replacement of this residue with a small aliphatic residue allowed the accommodation of other NTPs, resulting in the preferential use of dATP and the use of dCTP, a nucleotide not normally used. Results from this study suggest that the NTP must be stabilized by specific interactions within the NTP-binding site of the protein to achieve efficient hydrolysis. These interactions dictate NTP specificity.
Prediction of Cardiac and Noncardiac Mortality After Percutaneous Coronary Intervention (2015)

We report novel risk models to predict cardiac and noncardiac long-term mortality after percutaneous coronary intervention.
Towards a unified strategy for atrial fibrillation ablation?: reply (2005)

I thank Drs Pappone and Santinelli for their interest in my editorial titled ‘Towards more effective techniques for catheter ablation of atrial fibrillation: to aim for electrical disconnection of pulmonary veins or not’?1 The authors observe that adding ablation lines at the left posterior wall and the mitral isthmus to the anatomical circumferential ablation (ACA) catheter technique for the treatment of paroxysmal or persistent atrial fibrillation is associated with a significantly lower incidence (from 10.0 to 3.9%) of iatrogenic left atrial flutter during long-term …
Intraputamenal Cerebral Dopamine Neurotrophic Factor in Parkinson's Disease: A Randomized, Double‐Blind, Multicenter Phase 1 Trial (2023)

Intraputamenally administered CDNF was safe and well tolerated, and possible signs of biological response to the drug were observed in individual patients. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Water-Dispersed Single-Wall Carbon Nanohorns as Drug Carriers for Local Cancer Chemotherapy (2008)

These results suggest that water-dispersed oxSWNHs may thus be useful as a drug carrier for local chemotherapy.
Fronthaul Compression and Precoding Design for Full-Duplex Cloud Radio Access Network (2019)

In this paper, joint design of fronthaul compression and precoding is studied for full-duplex (FD) cloud radio access networks. Multiple uplink and downlink users equipped with multiple antennas communicate with a control unit (CU) in the “cloud” through a set of multiantenna FD radio units that are connected to the CU through limited capacity fronthaul links. In the first part of this paper, we address the weighted sum-rate maximization problem, to compute the optimal precoding and the quantization noise covariance matrices. By exploiting the relationship between weighted-sum-rate maximization and weighted minimum-mean-square-error minimization problems, and leveraging the successive convex approximation (SCA) method, we propose an iterative algorithm that guarantees convergence to a stationary point. In the second part of this paper, we address the stochastic sum-rate maximization problem under fast-fading channels, where only the statistics of the channel state information is available. Casting this nonconvex problem as a difference of convex problem, an iterative algorithm based on the combination of stochastic successive upper bound minimization and SCA approaches that guarantees convergence to a stationary point is proposed. Numerical results demonstrate the advantage of the proposed algorithms.
Neuropsychiatric systemic lupus erythematosus before and after immunosuppressive treatment: a FDG PET study (1998)

We describe a case of relapsing polychondritis with recurrent venous thrombosis associated with detectable anticardiolipin antibody. This association has not been previously reported, although venous and arterial thrombosis has been recognized in association with relapsing polychondritis.
Synthesis of single-phase layered oxychalcogenide La2CdO2Se2: crystal structure, optical and electrical properties (2004)

A single-phase La2CdO2Se2 powder was successfully synthesized and its optical and electrical properties were examined. Single-phase La2CdO2Se2 was obtained by preserving the stoichiometric composition of the initial ingredients, especially Cd and Se, during the sintering process. Exhibiting a yellowish white color, the synthesized sample has a large optical bandgap of ∼3.3 eV. The crystal structure, refined by a Rietveld method taking into account the site occupancies and isotropic thermal vibration parameters of Cd and Se, indicates that La2CdO2Se2 belongs to space group P42/nmc. Instability against Cd or Se vacancy formation makes it difficult to generate carriers through vacancies or allo-valent ions doping, leading to electrical insulating properties both in as-prepared and intentionally doped La2CdO2Se2 form.
Partial dysferlin reconstitution by adult murine mesoangioblasts is sufficient for full functional recovery in a murine model of dysferlinopathy (2010)

Dysferlin deficiency leads to a peculiar form of muscular dystrophy due to a defect in sarcolemma repair and currently lacks a therapy. We developed a cell therapy protocol with wild-type adult murine mesoangioblasts. These cells differentiate with high efficiency into skeletal muscle in vitro but differ from satellite cells because they do not express Pax7. After intramuscular or intra-arterial administration to SCID/BlAJ mice, a novel model of dysferlinopathy, wild-type mesoangioblasts efficiently colonized dystrophic muscles and partially restored dysferlin expression. Nevertheless, functional assays performed on isolated single fibers from transplanted muscles showed a normal repairing ability of the membrane after laser-induced lesions; this result, which reflects gene correction of an enzymatic rather than a structural deficit, suggests that this myopathy may be easier to treat with cell or gene therapy than other forms of muscular dystrophies.
Propane-1,3-di(magnesium halide) (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTPropane-1,3-di(magnesium halide)Lawrence C. Costa and George M. WhitesidesCite this: J. Am. Chem. Soc. 1977, 99, 7, 2390–2391Publication Date (Print):March 1, 1977Publication History Published online1 May 2002Published inissue 1 March 1977https://pubs.acs.org/doi/10.1021/ja00449a086https://doi.org/10.1021/ja00449a086research-articleACS PublicationsRequest reuse permissionsArticle Views284Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
극자외선 리소그라피에서의 Sub-resolution assist feature를 이용한 근접효과보정 (2016)

이 논문은 한국 정부 (MSIP)에서 후원하는 한국연구재단 (National Research Foundation of Korea, NRF) 의 기초연구 사업 (Grant No.2011-0028570)및 KLA-Tencor 사의 PROLITHTM 에 의하여 지원되었음.
Contact photolithographic micropatterning for bistable nematic liquid crystal displays (2008)

Orthogonal alignment patterns of 2×2μm2 size that induce nematic bistability were fabricated over 4×4cm2 by a double exposure process employing a rewritable photoalignment material. Bistable liquid crystal cells with patterned surfaces were fabricated, and reproducible switching between the bistable states driven by orthogonal in-plane electric fields at 8.2 and 3.9V∕μm was confirmed.
Relating Cascaded Random Forests to Deep Convolutional Neural Networks for Semantic Segmentation (2015)

We consider the task of pixel-wise semantic segmentation given a small set of labeled training images. Among two of the most popular techniques to address this task are Random Forests (RF) and Neural Networks (NN). The main contribution of this work is to explore the relationship between two special forms of these techniques: stacked RFs and deep Convolutional Neural Networks (CNN). We show that there exists a mapping from stacked RF to deep CNN, and an approximate mapping back. This insight gives two major practical benefits: Firstly, deep CNNs can be intelligently constructed and initialized, which is crucial when dealing with a limited amount of training data. Secondly, it can be utilized to create a new stacked RF with improved performance. Furthermore, this mapping yields a new CNN architecture, that is well suited for pixel-wise semantic labeling. We experimentally verify these practical benefits for two different application scenarios in computer vision and biology, where the layout of parts is important: Kinect-based body part labeling from depth images, and somite segmentation in microscopy images of developing zebrafish.
Photonic microstructures as laser mirrors (1998)

Deeply etched 1-D third-order Bragg reflectors have been used as mirrors for broad-area semiconductor lasers operating at 975-nm wavelength. From a threshold and efficiency analysis, we determine the mirror reflectivity to be approximately 95%. The design of the GaAs-based laser structure features three InGaAs quantum wells placed close (0.5 m) to the surface in order to reduce the required etch depth and facilitate high-quality etching. Despite the shallow design and the proximity of the guided mode to the metal contact, the threshold current density (J th 220 A/cm 2 for infinite cavity length) and internal loss ( i 91 cm 1 ) are very low.
New poly(ester-amide) copolymers modified with polyether (PEAE) for anticancer drug encapsulation (2016)

New poly(ester-amide) copolymers modified with polyethers were developed for carboplatin encapsulation. These new copolymers contain hydrophobic blocks made of tyrosine derivative and dimer fatty acid, and poly(ethylene glycol) (PEG) as hydrophilic blocks. Short-term hydrolytic degradation revealed high water absorption, slight increase of pH of simulated body fluid and change of sample shape, which indicated the erosive mechanism of polymers degradation. Poly(ester-amide)-PEG copolymers were used for microspheres preparation and carboplatin encapsulation. A double emulsification process was used to produce microspheres with an average diameter of 20-30 μm. It was found that the amount of drug released was controlled by the molecular mass of PEG used for microspheres preparation. Mathematical models were used to elucidate the release mechanism of the carboplatin from the microspheres. The results demonstrate that poly(ester-amide)-PEG copolymers may be used for targeted carboplatin encapsulation and release.
Laser Impact Welding (2012)

Laser impact welding is a solid-state, collision-based welding process. In this process, laser-generated optical energy is converted to kinetic energy through the ablation at the surface and confinement of the gas generated between a flyer and backing plate. The launch of the flyer can be affected by many factors, for example, backing material, ablative layer, and flyer thickness. In this paper, the effect of three backing materials: glass, polycarbonate and cellophane tape, were studied with different laser spot size and commercially pure aluminum alloy 1100 was used as the flyer. The results show that glass can provide the most efficient launches, but is damaged. Polycarbonate is a good compromise between efficiency and robustness. Welding is possible between many similar and dissimilar material pairs. In this study, commercially pure nickel was joined to commercially pure nickel. There are several possible geometric arrangements of the target relative to the flyer. With flat targets, metallurgical bonding takes place along the edges of the spot, and jet was observed in the center of the spot. Corrugated targets provide more surface area for metallurgical bonding. In this paper, the flyer launch velocity-time profile is also demonstrated using a photon Doppler velocimetry technique.
Synthesis of ent-Dioxepandehydrothyrsiferol (2010)

Dioxepandehydrothyrsiferol is a red alga metabolite derived from squalene. The unusual trans-anti-trans topography was constructed via a bromonium-initiated haloetherification cascade.
Hope, Hype and Help: Ethically Assessing the Growing Market in Stem Cell Therapies (2010)

http://dx.doi.org/10.1080/15265161.2010.481980
The effects of diet cycling on longevity (2010)

Introduction It has been suggested that diet cycling is unhealthy to the point that remaining obese is preferable to a fluctuating body weight. Objective To investigate the effects of diet cycling on longevity. Methods Male C57BL/6J mice were placed in one of three dietary regimes: a high fat (HF) diet, a low fat (LF) diet or a continuous diet cycle (4 weeks HF, 4 weeks LF). The diets were maintained for the entire lifespan of the mice. Body weight, food consumption, body composition, glucose tolerance and longevity were determined. Results As expected, body weight, body fat, food consumption and glucose tolerance were significantly elevated in the HF mice compared to LF controls. Diet cycling resulted in increases and decreases in the same parameters and the changes were concomitant with the HF and LF cycles. The HF and diet cycled mice consumed 61% and 20% more kcal/mouse/day than LF controls, respectively. At the time this abstract was written, 10% of the HF fed mice, 50% of the LF fed mice and 40% of the diet cycled mice remained alive, and the average lifespan of the HF, LF and diet cycled mice was 1.46, 2.38 and 2.15 years, respectively. Thus, the average lifespan of the HF fed mice was decreased by 38.7% compared to LF controls, while the diet cycled mice only exhibited a 9.7% decrease. Conclusions Since diet cycled mice lived longer than non‐diet cycled mice on a HF diet, diet cycling was healthier with respect to lifespan than not “dieting” at all. This work was supported in part by the State of Ohio's Eminent Scholar Program that includes a gift from Milton and Lawrence Goll, by the AMVETS, by the Diabetes Research Initiative at Ohio University, and by NIH grants DK075436, AG019899, AG031736.
New cellular therapies: Is there a role for transfusion services? (2009)

International audience
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly (2010)

A recently identified variant within the fat mass and obesity-associated (FTO) gene is carried by 46% of Western Europeans and is associated with an approximately 1.2 kg higher weight, on average, in adults and an approximately 1 cm greater waist circumference. With >1 billion overweight and 300 million obese persons worldwide, it is crucial to understand the implications of carrying this very common allele for the health of our aging population. FTO is highly expressed in the brain and elevated body mass index (BMI) is associated with brain atrophy, but it is unknown how the obesity-associated risk allele affects human brain structure. We therefore generated 3D maps of regional brain volume differences in 206 healthy elderly subjects scanned with MRI and genotyped as part of the Alzheimer's Disease Neuroimaging Initiative. We found a pattern of systematic brain volume deficits in carriers of the obesity-associated risk allele versus noncarriers. Relative to structure volumes in the mean template, FTO risk allele carriers versus noncarriers had an average brain volume difference of approximately 8% in the frontal lobes and 12% in the occipital lobes-these regions also showed significant volume deficits in subjects with higher BMI. These brain differences were not attributable to differences in cholesterol levels, hypertension, or the volume of white matter hyperintensities; which were not detectably higher in FTO risk allele carriers versus noncarriers. These brain maps reveal that a commonly carried susceptibility allele for obesity is associated with structural brain atrophy, with implications for the health of the elderly.
A new assessment of the use of wide bandgap semiconductors and the potential for GaN (2003)

An advantage for some wide bandgap materials, that is often overlooked, is that the thermal coefficient of expansion (CTE) is better matched to the ceramics in use for packaging technology. It is shown that the optimal choice for uni-polar devices is clearly GaN. It is further shown that the future optimal choice for bipolar devices is C (diamond). A new expression relating the critical electric field for breakdown in abrupt junctions to the material bandgap energy is derived and is further used to derive new expressions for specific on-resistance in power semiconductor devices. These new expressions are compared to the previous literature and the efficacy of specific power devices, such as heterojunction MOSFETs, using GaN are discussed.
On Partial Sums in Cyclic Groups (2015)

We are interested in ordering the elements of a subset A of the non-zero integers modulo n in such a way that all the partial sums are distinct. We conjecture that this can always be done and we prove various partial results about this problem.
Enantioselective Construction of Indanones from Cyclobutanols Using a Rhodium-Catalyzed C-C/C-H/C-C Bond Activation Process (2010)

Enantioselective rhodium(I)-catalyzed reactions of tert-cyclobutanols, e.g. I, lead to indanones with quaternary stereogenic centers, e.g. II, via consecutive C-C/C-H/C-C bond activations.
Contents, Vol. 37, 1983 (1983)

Drug DosageThe authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication.However, in view of ongoing research, changes in government regulations, and the con stant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any change in indications and dosage and for added warnings and precautions.This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Dynamic Analysis of Vascular Morphogenesis Using Transgenic Quail Embryos (2010)

The present results offer a powerful approach to the major challenge of studying the relative role(s) of the mechanical, molecular, and cellular mechanisms of vascular development. In past studies, the advantages of the molecular genetic tools available in mouse were counterbalanced by the limited experimental accessibility needed for imaging and perturbation studies. Avian embryos provide the needed accessibility, but few genetic resources. The creation of transgenic quail with labeled endothelia builds upon the important roles that avian embryos have played in previous studies of vascular development.