gebhart/patrepeval huggingface dataset:
Estimation of Spectral Reflectance From Densitometric Measurements Using Printing Model Prior (2009)

Estimating the spectral reflectance of a printed patch is an important task in the printing industry for several purposes such as ICC profiling and maintaining color consistency. However, equipment for accurate spectral reflectance estimation (spectrophotometers) is expensive. In this work we suggest to use known characterization of the printer output in order to achieve accurate estimation of spectral reflectance from only three-channel measurement, such as provided by the standard status T densitometers.The mean estimation error we achieve on known substrates is 0.13&#x394;E. Further results indicate an estimation error below 1&#x394;E for a set of unknown substrates.
Free-standing metal–organic framework (MOF) monolayers by self-assembly of polymer-grafted nanoparticles (2020)

We report a general method for the synthesis of free-standing, self-assembled MOF monolayers (SAMMs) at an air-water interface using polymer-brush coated MOF nanoparticles. UiO-66, UiO-66-NH<sub>2</sub>, and MIL-88B-NH<sub>2</sub> were functionalized with a catechol-bound chain-transfer agent (CTA) to graft poly(methyl methacrylate) (PMMA) from the surface of the MOF using reversible addition-fragmentation chain transfer polymerization (RAFT). The polymer-coated MOFs were self-assembled at the air-water interface into monolayer films ∼250 nm thick and capable of self-supporting at a total area of 40 mm<sup>2</sup>. Mixed-particle films were prepared through the assembly of MOF mixtures, while multilayer films were achieved through sequential transfer of the monolayers to a glass slide substrate. This method offers a modular and generalizable route to fabricate thin-films with inherent porosity and sub-micron thickness composed of a variety of MOF particles and functionalities.
P3‐423: LRRK2 regulates the stress response in C. elegans and mammalian cells (2008)

Mutations in leucine-rich repeat kinase 2 (LRRK2) have been identified to cause late-onset Parkinsons disease (PD), and lead to inclusions containing either alpha-synuclein or tau protein. The LRRK2 kinase domain is highly homologous to that of the mixed-lineage kinases (MLKs), which are MAPKKKs that act upstream of MAPKKs in the mitogen-activated protein kinase (MAPK) pathway. We generated lines of C. elegans expressing neuronally directed human LRRK2 and observed striking differences in responses to stresses associated with PD. To analyze potential mechanisms of action, we used co-immunoprecipitation and luciferase reporter assays and investigated the regulation of MAPK signaling by LRRK2. LRRK2 constructs (WT, G2019S, R1441C, kinase dead) were expressed in C. elegans driven by the neuronal specific synaptobrevin promoter. The WT and G2019S lines were integrated, while the other lines were expressed as arrays. C. elegans lines were also crossed to lines carrying GFP driven by the dopamine transporter promoter. For mammalian cell work, epitope tagged LRRK2 constructs were transiently expressed in 293 cells. Expressing LRRK2 strongly potentiated toxicity caused by tunicamycin, heat shock or proteasomal inhibition, which are stresses associated with increased protein misfolding. LRRK2 expression protected C. elegans against agents causing mitochondrial dysfunction, such as rotenone or paraquat, but protection by G2019S LRRK2 was less than protection by wild type LRRK2. In each case, knockdown of lrk-1, the C. elegans homologue of LRRK2 produced the opposite effect. Disease related mutations in LRRK2 specifically increased susceptibility of dopaminergic neurons. Binding studies in mammalian cells indicate that LRRK2 binds to MKK3, 6 and 7, which are upstream kinases regulating the p38 and JNK signaling cascades. LRRK2 appears to act by regulating the subcellular localization of the MKKs. Knockdown of the C. elegans equivalent of p38 or JNK abrogated the actions of LRRK2 in C. elegans. Our data indicate that LRRK2 modulates the p38 and JNK stress kinase cascades through interaction with MKK3, 6 and 7, and this regulation allows LRRK2 to modulate the response of neurons to stresses associated with neurodegenerative disease.
Shape Evasion: Preventing Body Shape Inference of Multi-Stage Approaches (2019)

Modern approaches to pose and body shape estimation have recently achieved strong performance even under challenging real-world conditions. Even from a single image of a clothed person, a realistic looking body shape can be inferred that captures a users' weight group and body shape type well. This opens up a whole spectrum of applications -- in particular in fashion -- where virtual try-on and recommendation systems can make use of these new and automatized cues. However, a realistic depiction of the undressed body is regarded highly private and therefore might not be consented by most people. Hence, we ask if the automatic extraction of such information can be effectively evaded. While adversarial perturbations have been shown to be effective for manipulating the output of machine learning models -- in particular, end-to-end deep learning approaches -- state of the art shape estimation methods are composed of multiple stages. We perform the first investigation of different strategies that can be used to effectively manipulate the automatic shape estimation while preserving the overall appearance of the original image.
Chloroquine enjoys a renaissance as an antineoplastic therapy (2013)

Chloroquine (CQ) and hydroxychloroquine (HCQ), oral lysosomotropic agents with well-studied toxicity profiles, and antimalarial and antirheumatic activity, have been repurposed as antineoplastic agents based on preclinical data showing efficacy in preinvasive cancer, cancer stem cells and metastatic cancer. Phase I/II clinical trials are providing safety and efficacy data regarding CQ or HCQ monotherapy or combination therapy with molecularly targeted inhibitors in patients diagnosed with glioblastoma multiforme, breast ductal carcinoma in situ, non-small-cell lung cancer, hepatocellular, pancreatic, or renal cancer, multiple myeloma, or chronic lymphocytic leukemia. Disruption of autophagy-mediated cell survival is a major therapeutic rationale for using CQ and HCQ. CQ and HCQ are the first agents that rationally target cytoprotective autophagy in cancer. Short-term treatment of preinvasive breast cancer with CQ introduces the concept of preventing invasive cancer by killing preinvasive lesions.
The Diabetic Foot (2018)

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Controlled switching of ferroelectric SnSe monolayers at room temperature (2020)

Two-dimensional (2D) van der Waals ferroelectrics provide an unprecedented architectural freedom for the creation of artificial multiferroics and non-volatile electronic devices based on vertical and co-planar heterojunctions of 2D ferroic materials. Additionally, their non-centrosymmetric structures lead to a strong non-linear optical response, and also add functionalities to designer spintronic and valleytronic devices. Nevertheless, controlled electrical switching of in-plane polarization--a fundamental requirement for realizing in-plane ferroelectric non-volatile memories--has not yet been seen experimentally in any monolayer-thick 2D ferroelectric. Here we report the discovery of robust ferroelectricity with a critical temperature close to 400 K in SnSe monolayer plates, and the demonstration of controlled ferroelectric switching of their in-plane spontaneous polarization at room temperature using a scanning tunneling microscope (STM). The switching was achieved through creating, moving and eliminating 180° domain walls in the SnSe monolayer plates by applying appropriate bias voltage pulses to an STM tip. This study shows that STM is a powerful tool for detecting and manipulating the in-plane polarization in 2D ferroelectric monolayers, which is difficult to characterize by conventional approaches such as piezoresponse force microscopy, thus facilitating the hunt for other 2D ferroelectric monolayers with in-plane polarization with important technological applications.
Restoration of allograft responsiveness in B rats by interleukin 2 and/or adherent cells. (1982)

LEW X BN)F1 cardiac allografts survive 1 wk in unmodified LEW recipients (MST +/- SD = 8.3 +/- 1.2 days) but indefinitely (greater than 100 days) in B rats, produced by 750 R sublethal x-radiation 3 to 4 wk after adult thymectomy and reconstitution with syngeneic bone marrow cells from thymectomized thoracic duct-drained donors. Graft survival appears independent of blocking antibodies and is not mediated by suppressor cells or loss of graft immunogenicity. The unresponsive state is eventually reversed by adoptive transfer of 10(8) spleen cells from nonimmune (MST +/- SD = 27.5 +/- 4.7 days) or alloimmune (MST +/- SD = 21.5 +/- 1.9 days) syngeneic animals. In contrast, concomitant administration of 2 X 10(7) thioglycollate-stimulated peritoneal exudate adherent cells plus 10(8) alloimmune syngeneic spleen cells produced acute allograft rejection in 50% of B recipients within 10 to 12 days, while in every instance grafts underwent acute rejection (MST +/- SD = 10.0 +/- 1.4 days) in B recipients treated with interleukin 2 (IL 2) rich conditioned supernatant plus sensitized cells. In vitro studies revealed that adherent cells from B rats possessed less than 50% the capacity of adherent cells from normal animals either to support the Con A-stimulated uptake of 3H-thymidine by splenic T cells or to promote production of IL 2 by spleen cells depleted of adherent cells. Altered lymphocyte migration patterns in B recipients may also contribute to prolonged allograft survival secondary to adherent cell dysfunction.
Correlated Topics in a Scalable Multidimensional Text Cube: Algorithms and Aviation Safety Case Study (2010)

Many organizations have large text repositories that contain information that is mission critical to the organization. NASA, for example, operates a safety reporting system known as the Aviation Safety Reporting System (ASRS) which collects voluntarily submitted aviation safety incident/situation reports from pilots, controllers, and others with the purpose to identify system-wide
Data analytics and machine learning: root-cause problem-solving approach to prevent yield loss and quality issues in semiconductor industry for automotive applications (2021)

Quality requirements in the semiconductor industry for automotive products are increasing rapidly with the movement to autonomous vehicles and higher levels of safety. It is no longer possible to express maximum failure requirements in parts per million (ppm). Individual failing parts observed in the field and reported by customers can trigger a significant quality response. ‘Zero-defect’ (ZD) is no longer considered a utopian ideal, but a required potentially reachable goal for semiconductor manufacturers. Projects and studies that include artificial intelligence and big data, are seen as key drivers to reach a ZD level of quality. Competing objectives targeted in any industrial project, such as quality improvement and gross margin, must also be considered. Initial projects in machine learning (ML), focusing on yield-loss issues, are being deployed within the manufacturing sites. These projects interconnect typical internal data collected from the manufacturing and assembly lines with engineering, qualification and reliability data. For a specific case study of unexpected abnormally high variability on some parameters, this paper presents a problem-solving approach in a big-data environment. Models implemented and results obtained towards root-cause problem solving for this issue, are discussed. This overall approach may be replicated in other ML projects.
High-Pressure57Fe Mössbauer Spectroscopy of LaFeAsO (2009)

The electronic properties of an oxypnictide, LaFeAsO, pressurized in a diamond-anvil cell, were investigated by 57 Fe Mössbauer spectroscopy and electrical resistance measurements at pressures up to 24 and 35 GPa, respectively. The Néel temperature gradually decreased from ∼140 K at 0.1 MPa to ∼50 K at 20 GPa, and fell below 8 K or disappeared at 24 GPa. The hyperfine field at 8 K decreased from 5.3 T at 0.1 MPa to 2.2 T at 20 GPa. On the other hand, the onset of superconductivity occurred at ∼9 K at 2 GPa. The superconductivity peaked at ∼21 K at 12 GPa, and then began a perceptible decline, disappearing at ∼35 GPa. This suggests that suppression of antiferromagnetic order plays an important role in the emergence of pressure-induced superconductivity.
Flow-Based Admission Control Algorithm in the DiffServ-Aware ATM-Based MPLS Network (2002)

This paper proposes a flow-based admission control algorithm through an Asynchronous Transfer Mode (ATM) based Multi-Protocol Label Switching (MPLS) network for multiple service class environments of Integrated Service (IntServ) and Differentiated Service (DiffServ). We propose the Integrated Packet Scheduler to accommodate IntServ and Best Effort traffic through the DiffServ-aware MPLS core network. The numerical results of the proposed algorithm achieve reliable delay-bounded Quality of Service (QoS) performance and reduce the blocking probability of high priority service in the DiffServ model. We show the performance behaviors of IntServ traffic negotiated by end users when their packets are delivered through the DiffServ-aware MPLS core network. We also show that ATM shortcut connections are well tuned with guaranteed QoS service. We validate the proposed method by numerical analysis of its performance in such areas as throughput, end-to-end delay and path utilization.
A new approach for iris segmentation (2008)

Iris segmentation is an important first step for high accuracy iris recognition. A robust iris segmentation procedure should be able to handle noise, occlusion and non-uniform lighting. It also impacts system accuracy — high FAR or FRR values may come directly from bad or wrong segmentations. In this paper a simple new approach for iris segmentation is proposed that tries to integrate quality evaluation ideas directly into the segmentation algorithm. By cutting out all the bad areas, the fraction of the iris that remains can be used as a comprehensive quality measure. This eliminates images with high occlusion (e.g. by the eyelids) as well as images with other quality problems (e.g. low contrast), all using the same mechanism. The proposed method has been tested on a medium-sized (450 image) public database (MMU1) and the score distribution investigated. We also show that, as expected, overall matching accuracy can be improved by rejecting images which have a low quality assessment, thus validating the utility of this measure.
Subject Index (2014)

You have accessPolymer RheologyNov 2014Subject IndexTim Osswald, Natalie RudolphTim Osswald, Natalie Rudolphhttps://doi.org/10.3139/9781569905234.bmSectionsAboutPDF ToolsAdd to FavoritesDownload CitationTrack CitationsCopy LTI LinkPDF key 'share (en)' returned an object instead of string.FacebookTwitterEmailLinkedIn previous chapter FiguresReferencesRelatedDetails 2014Pages: 221-225Print ISBN: 978-1-56990-517-3eISBN: 978-1-56990-523-4 Copyright & Permissions© 2015 Carl Hanser Verlag GmbH & Co. KGPDF downloadLoading ...
Physical properties of alpine snow as related to weather and avalanche conditions / (1971)

Data were taken in avalanche starting zones at an elevation of 1 1,700 feet in Front Range of Colorado within 14 days of deposition.Densities varied from 40 to 450 kg m~3.A statistical criterion was used to identify snow with unusually high density for its age (initial hard slab) and unusually low (persistent soft snow).Initial hard slab, found in 15 percent of the pits, was correlated with moderate to high windspeeds, low temperatures, and presence of wind-transported snow.No good way was found to distinguish initial hard slab from dense older snow.Tensile strength from a spin test varied from 1.0 to 1712 grams force cm 2 .Strength increased with density but varied greatly for given density.Younger snows tended to be weaker than older snows of same density.Strength was also measured with shear box and shear vane.Ram resistance was higher for alpine snow than for , snow of same density in the trees.Air permeability was an order of magnitude less than expected and varied with the low flow rate used.The ratio virtual porosity/porosity, which averaged 1.062, was of little value for identifying wind slab.Strength of snow of given density was greater for a certain permeability (texture) than for any other.
Accessibility validation with RAVEN (2006)

Testing is, for most, a necessary evil in the software life cycle. One very important form of testing is the evaluation of software products according to mandated criteria or guidelines such as those that specify level of accessibility. Such evaluations can be quite tedious, especially if they must be done manually and applied consistently to each and every component of an application. The use of assistive technologies like screen readers to demonstrate the compliance of a software product to a set of regulations is time-consuming, error-prone, and expensive. Validation tools that can perform such evaluations are becoming more popular as integrated development environments become more sophisticated but, in the area of accessibility validation, they are sorely lacking if not nonexistent. This paper introduces the IBM Rule-based Accessibility Validation Environment, an Eclipse-based tool for inspecting and validating Java rich-client GUIs for accessibility using non-invasive, semi- to fully-automatic, rule-based validation and inspection.
The effect of rhodium precursor on Rh/Al2O3 catalysts (1982)

The infrared spectra of the CO/Rh/Al2O3 system have been examined following several different means of preparing the supported rhodium catalyst. Rhodium precursor materials including RhCl3 ⋅ 3H2O, Rh(NO3)3 ⋅ 2H2O, Rh6(CO)16, [Rh(OCOCH3)2]2, and Rh2(SO4)3 have been compared as to their tendencies to produce upon reduction the various CO/Rh/Al2O3 species generally attributed to this catalytic system. The nitrate and carbonyl precursors are most easily reduced to rhodium metal. The acetate and sulfate anions poison the Rh/Al2O3 surface through decomposition during reduction leading to very minimal CO adsorption. The catalytic properties of Rh/Al2O3 could be quite dependent upon the nature of rhodium precursor chosen.
Endoscopic Application of a Compact Compound-Eye Camera (2015)

A multi-functional compound-eye endoscope enabling multi-spectral imaging and variable field-of-view is presented, which is based on a compact compound-eye camera called TOMBO (thin observation module by bound optics). Narrow-band filters attached to some lenses provide snap-shot multi-band images. Fixed and movable mirrors are introduced to control the field of view, which realizes several observation modes such as three-dimensional shape measurement, wide field-of-view, and close-up observation.
Contents, Vol. 12, 1985-86 (1985)

Drug Dosage
The renal blood flow and the glomerular filtration rate of anaesthetized dogs during acute changes in plasma sodium concentration (1976)

1. The effects of acute changes in plasma Na concentration ( P Na ) on renal blood flow (RBF) and glomerular filtration rate (GFR) were studied in anaesthetized greyhounds. Saline was infused at a constant rate (0·1 ml. kg −1 min −1 ) either into a renal artery or into a systemic vein. Plasma Na concentration was altered by varying the Na concentration of the infused saline from 0·154 to 0·077, 0·616 or 1·232 M . 2. Blood pressure (B.P.), packed cell volume (PCV), concentration of plasma solids (PS) and the plasma concentration of H + and K ( P K ) ions were measured but no attempt was made to contain their fluctuation. 3. An infusion of hypertonic saline into a renal artery usually led to an ipsilateral increase in RBF for 5‐15 min, followed by a progressive fall. Over‐all, mean values of RBF fell with P Na throughout the range studied (120‐190 m‐mole l. −1 ). Glomerular filtration rate rose with P Na to reach maximal values at P Na levels of 140‐160 m‐mole l. −1 , but fell thereafter. The combined fall in RBF and GFR, without change in filtration fraction, at P Na values above 160 m‐mole l. −1 is consistent with an alteration in afferent arteriolar resistance. The fall in GFR despite a rise in RBF noted when P Na was reduced below 140 m‐mole l. −1 requires an additional explanation. 4. Renal blood flow was independent of P K ; it was inversely related to [H + ] and directly related to PS. Glomerular filtration rate was independent of PCV and P K . It was also inversely related to [H + ] and directly related to PS up to a value of 6 g 100 g −1 plasma, after which the relationship was reversed. These results suggest that the renal vascular responses to acute changes in P Na may be mediated in part, at least, by concurrent change in PS and [H + ].
Comparative Epigenomics Reveals that RNA Polymerase II Pausing and Chromatin Domain Organization Control Nematode piRNA Biogenesis (2019)

Piwi-interacting RNAs (piRNAs) are important for genome regulation across metazoans, but their biogenesis evolves rapidly. In Caenorhabditis elegans, piRNA loci are clustered within two 3-Mb regions on chromosome IV. Each piRNA locus possesses an upstream motif that recruits RNA polymerase II to produce an ∼28 nt primary transcript. We used comparative epigenomics across nematodes to gain insight into the origin, evolution, and mechanism of nematode piRNA biogenesis. We show that the piRNA upstream motif is derived from core promoter elements controlling snRNA transcription. We describe two alternative modes of piRNA organization in nematodes: in C. elegans and closely related nematodes, piRNAs are clustered within repressive H3K27me3 chromatin, while in other species, typified by Pristionchus pacificus, piRNAs are found within introns of active genes. Additionally, we discover that piRNA production depends on sequence signals associated with RNA polymerase II pausing. We show that pausing signals synergize with chromatin to control piRNA transcription.
Use of Natural Antimicrobials from a Food Safety Perspective for Control of Staphylococcus aureus (2011)

Staphylococcus aureus (S. aureus) is an important foodborne and environmental pathogen that can produce toxins in foods and cause infections in soft tissues. S. aureus that have developed resistance to the conventional antimicrobials are commonly called Methicillin-Resistant Staphylococcus aureus (MRSA) and Vancomycin-Resistant S. aureus (VRSA). Their prevalence is believed to be due to the widespread use of antibiotics. Therefore, natural antimicrobials are in urgent demand as alternatives to conventional antibiotics to treat S. aureus infections. In this review, natural antimicrobials from plant, animal and microbiological origins are discussed, including their mode of action and mechanisms of bacterial resistance, major components, chemical structure, effectiveness, synergistic effects and future prospects.