gebhart/patrepeval huggingface dataset:
Induktion von Ferroelektrizität in Polymersystemen durch Wasserstoffbrückenbindungen (1992)

Achirale Polysiloxane mit para ‐Alkoxybenzoesäure‐Seitengruppen können über Wasserstoffbrückenbindungen viele Moleküle eines optisch aktiven trans ‐Stilbazols binden. Das durch Selbstorganisation resultierende System 1 zeigt ferroelektrische Eigenschaften, die sich über die Zahl der Stilbazoleinheiten pro Polymermolekül und die Länge der (CH 2 ) n ‐Spacer steuern lassen. magnified image
Mapping of Local Cerebral pH with Positron Emission Tomography (2021)

Animal studies have demonstrated disturbances in acid/base balance resulting from experimental ischemic injury. Local alterations in brain pH may also arise in association with neoplastic tissue. The pH of the tissue environment may also play a role in radiation therapy and hyperthermia, with evidence that tumor cells may be less radiation sensitive but more heat sensitive at low pH. The standard methods for measuring brain pH in animals cannot be used in man because they are too invasive, requiring either tissue samples or placement of microelectrodes. pH studies have also been performed on patients with primary and metastatic brain tumors to assess acid-base status. The role of pH measurements in evaluating cerebral tumors is not yet clear. The predictive ability of pH data has not been established. There is abundant evidence that the sequence of events referred to as stroke is triggered by an interruption or severe decrease in blood flow to tissue in the brain.
Screening of human brain tumors for SV40‐related T antigen (1978)

A series of 39 human brain tumors has been screened for the presence or absence of SV40-related T antigen by the direct and indirect immunoperoxidase methods. Two tumors of ependymal origin (malignant ependymoma, choroid plexus papilloma) revealed markedly positive nuclear staining for T antigen both in vivo and in vitro. The relationship of these tumors to their experimental counterparts inducible by recent human papovavirus isolates is discussed.
An Experiment in Semantic Tagging using Hidden Markov Model Tagging (1997)

The same word can have many different meanings depending on the context in which it is used. Discovering the meaning of a word, given the text around it, has been an interesting problem for both the psychology and the artificial intelligence research communities. In this article, we present a series of experiments, using methods which have proven to be useful for eliminating part-of-speech ambiguity, to see if such simple methods can be used to resolve semantic ambiguities. Using a publicly available semantic lexicon, we find the Hidden Markov Models work surprising well at choosing the right semantic categories, once the sentence has been stripped of purely functional words.
Bloedziekten (2016)

Agamma- en hypogammaglobulinemie, zie hoofdstuk 9: Agamma- en hypogammaglobulinemie.
Influence of Age and Health on Immune Functions and Trace Elements (1995)

Apparently healthy elderly donors were screened according to a simple protocol that included clinical examination and the determination of hematological and biochemical values. This screening was performed to detect subclinical alterations which might interfere with immune responses and trace element status. The elderly were divided into two groups. The first group consisted of 22 (age 76 +/- 1 years) positively selected elderly (PSE), i.e. healthy subjects with no hematological and laboratory alterations, the second one comprised 13 (age 75 +/- 1 years) negatively selected elderly (NSE). Data were then compared with those obtained from 40 (age 35 +/- 2 years) healthy young controls. In both groups of elderly donors, plasma zinc levels were normal, while plasma copper concentrations were increased. Intracellular values of zinc and copper in mono- and polymorphonuclear cells from both groups of elderly were within reference limits. After in vitro activation, granulocyte chemiluminescence activity was impaired only in NSE. A decrement in the number of circulating CD3 lymphocytes and an increase in CD8d, CD57 cells were found in PSE, while NSE showed an increased number of CD3,DR cells and CD8d, CD57, CD8b,CD57 and CD16,CD56 positive cells. Our results indicate that only plasma copper levels were affected by age, whereas subclinical alterations in hematological or biochemical values appear to impair immune responses in the elderly.
An architecture of reconfigurable transceiver based on digital IF for WCDMA and IS-95 base stations (2003)

We have presented the architecture of a reconfigurable transceiver based on digital IF for wideband code division multiple access (WCDMA) and IS-95 CDMA base stations. The presented transceiver has been designed to support multiple frequency allocations (FA) at multiple standards without modifications of hardware as in software defined radio (SDR) concepts. A bandpass sampling technique has been applied to the presented receiver to use an analog to digital converter with lower sampling rate. Also, the digital complex quadrature modulation technique that is able to reject image frequency components is used to apply the baseband adaptive predistorter in digital baseband processing in the presented transmitter. The simulation using a simplified channel structure has been performed to certify the presented transceiver architecture structure by back-to-back connection of the transmitter and receiver.
NVRAM-aware logging in transaction systems (2014)

Emerging byte-addressable, non-volatile memory technologies (NVRAM) like phase-change memory can increase the capacity of future memory systems by orders of magnitude. Compared to systems that rely on disk storage, NVRAM-based systems promise significant improvements in performance for key applications like online transaction processing (OLTP). Unfortunately, NVRAM systems suffer from two drawbacks: their asymmetric read-write performance and the notable higher cost of the new memory technologies compared to disk. This paper investigates the cost-effective use of NVRAM in transaction systems. It shows that using NVRAM only for the logging subsystem ( NV-Logging ) provides much higher transactions per dollar than simply replacing all disk storage with NVRAM. Specifically, for NV-Logging , we show that the software overheads associated with centralized log buffers cause performance bottlenecks and limit scaling. The per-transaction logging methods described in the paper help avoid these overheads, enabling concurrent logging for multiple transactions. Experimental results with a faithful emulation of future NVRAM-based servers using the TPCC, TATP, and TPCB benchmarks show that NV-Logging improves throughput by 1.42 - 2.72x over the costlier option of replacing all disk storage with NVRAM. Results also show that NV-Logging performs 1.21 - 6.71x better than when logs are placed into the PMFS NVRAM-optimized file system. Compared to state-of-the-art distributed logging, NV-Logging delivers 20.4% throughput improvements.
Design of an Emergency Wake-up Alert System Utilizing Digital Television Guard Band (2016)

In this paper, we propose an emergency wake-up alert system (EWAS) for providing accurate and rapid emergency information. The proposed system can provide an emergency wake-up alert service without an additional frequency allotment by utilizing the guard band of the Advanced Television Systems Committee (ATSC) Terrestrial Digital Television (DTV) system. The design target of the proposed system is to match the indoor reception coverage of EWAS with the outdoor reception coverage of the ATSC DTV system. To achieve this, the proposed system should be about 35.65 dB more robust than the ATSC DTV system. The simulation results show that the proposed system offers an emergency wake-up alert service supporting a data rate of up to 23 bps.
Genistein-Induced Apoptosis of p815 Mastocytoma Cells Is Mediated by Bax and Augmented by a Proteasome Inhibitor, Lactacystin (2002)

Although genistein has been demonstrated to induce apoptosis of various cells, there is no report of its effect on mast cell proliferation. Here we show that genistein reduced the viability of mast cell tumor cell lines, p815 and RBL-2H, but not of a human mast cell line, HMC-1. Further investigation on its growth-inhibitory mechanism was undertaken on p815 mastocytoma cells. Genistein induced G2/M arrest and subsequent apoptotic death. p815 cells undergoing apoptosis showed many apoptotic manifestations, such as reduction of mitochondrial membrane potential, release of cytochrome c to cytosol, translocation of apoptosis-inducing factor to nucleus, activation of caspase-3, nuclear condensation, and generation of DNA fragmentation. Genistein treatment resulted in the increase of Bax expression and its translocation into mitochondria, whereas expression levels of Bcl-2 remained unchanged. Proteasome activity decreased at the early time points after genistein treatment, but thereafter it fluctuated at increased levels. A proteasome inhibitor, lactacystin, potentiated the induction of apoptosis. Taken together, genistein-induced apoptosis of p815 mastocytoma cells is at least in part mediated by proteasome, Bax, apoptosis-inducing factor, and caspase and augmented by cotreatment with a proteasome inhibitor, lactacystin.
Correlated giant dielectric peaks and antiferromagnetic transitions near room temperature in pure and alkali-doped BaMnO3−δ (2011)

We report structural, magnetic, dielectric and thermal properties of single-crystal BaMnO(2.99) and its derivatives BaMn(0.97)Li(0.03)O(3) and Ba(0.97)K(0.03)MnO(3). The hexagonal 15R-BaMnO(2.99) perovskite phase is a known antiferromagnetic insulator that orders at a Néel temperature T(N) = 220 K. We find dilute Li and K doping change the ratio of cubic to hexagonal layers and cause drastic changes in the dielectric and magnetic properties. Unusually large high-temperature magnetoelectric shifts (up to 85%) are observed near temperatures at which pronounced peaks in the dielectric constant are observed for applied electric fields along either the c or a axis, respectively. The temperatures of the dielectric peaks are strongly correlated with anomalies in the c- or a-axis magnetic susceptibility and the specific heat for all compositions studied. All our data suggest that the strongly anisotropic magnetic and dielectric anomalies (which occur near, or above room temperature) originate from the same Mn ion sites, which implies these materials form an exceptional class of magnetoelectrics.
Supplementary Figure 1 from Assembly and Initial Characterization of a Panel of 85 Genomically Validated Cell Lines from Diverse Head and Neck Tumor Sites (2023)

&lt;p&gt;PDF file - 5.04MB&lt;/p&gt;
Heat Transfer and Pressure Loss Characteristics of Very Compact Heat Sinks. (1998)

High-performance compact heat sinks have been developed for effective cooling of high-density LSI packaging. Heat transfer and pressure loss characteristics of the heat sinks in both air-cross flow and air-jet cooling have been experimentally studied. The present heat sinks were of plate-fin and pin-fin arrays with a fin pitch of 0.7 mm. The plate-fin heat sinks had higher cooling performance than the pin fin heat sinks in the range of large air flow rate both in air-cross flow and air-jet cooling. The thermal conductance in cross-flow cooling was 20 or 40% larger than that in jet cooling. The correlation of Colburn j-factor/Fanning friction factor vs. the Reynolds number for the present heat sinks was found to be very close to that of a conventional large size heat exchanger.
Low temperature carbon co-implantation in silicon: Defects suppression and diffusion modeling (2021)

Carbon has been co-implanted to phosphorus at low temperature (−100 °C) in silicon. As compared to a room temperature carbon implant, phosphorus activation is increased due to the suppression of extended defects. The unusual carbon depleted region observed in both secondary ion mass spectroscopy and atom probe tomography annealed profiles has been explained and modeled using an interstitialcy diffusion barrier of 0.6 eV. Carbon clusters have been interpreted as being composed of several immobile dimers carbon/self-interstitial, in agreement with the stoichiometry of the SiC phase. From the model presented here, an adequate temperature window (&amp;gt;750 °C) has been found regarding self-interstitials trapping by carbon.
Size-Tunable Silicon/Iron Oxide Hybrid Nanoparticles with Fluorescence, Superparamagnetism, and Biocompatibility (2011)

Magnetic/fluorescent composite materials have become one of the most important tools in the imaging modality in vivo using magnetic resonance imaging (MRI) monitoring and fluorescence optical imaging. We report herein on a simplified procedure to synthesize hybrid nanoparticles (HNPs) that combine silicon and magnetic iron oxides consisting of magnetite (Fe(3)O(4)) and maghemite (γ-Fe(2)O(3)). Intriguingly, our unique synthetic approach can control magnetic and optical behaviors by reducing the particle size, demonstrating that the HNPs with the mean diameter of 3.0 nm exhibit superparamagnetic behavior and green fluorescence in an aqueous solution, ambient air, and a cellular environment, whereas the HNPs with the mean diameter more than 5.0 nm indicate ferromagnetic behavior without fluorescence. Additionally, both HNPs with different diameters possess excellent magnetic responsivity for external applied magnetic field and good biocompatibility due to the low cytotoxicity. Our biocompatible HNPs with the superparamagnetism can provide an attractive approach for diagnostic imaging system in vivo.
InfoCNF: An Efficient Conditional Continuous Normalizing Flow with Adaptive Solvers (2019)

Continuous Normalizing Flows (CNFs) have emerged as promising deep generative models for a wide range of tasks thanks to their invertibility and exact likelihood estimation. However, conditioning CNFs on signals of interest for conditional image generation and downstream predictive tasks is inefficient due to the high-dimensional latent code generated by the model, which needs to be of the same size as the input data. In this paper, we propose InfoCNF, an efficient conditional CNF that partitions the latent space into a class-specific supervised code and an unsupervised code that shared among all classes for efficient use of labeled information. Since the partitioning strategy (slightly) increases the number of function evaluations (NFEs), InfoCNF also employs gating networks to learn the error tolerances of its ordinary differential equation (ODE) solvers for better speed and performance. We show empirically that InfoCNF improves the test accuracy over the baseline while yielding comparable likelihood scores and reducing the NFEs on CIFAR10. Furthermore, applying the same partitioning strategy in InfoCNF on time-series data helps improve extrapolation performance.
Lens-term- and edge-effect in X-ray grating interferometry (2015)

X-ray grating interferometry requires gratings with periods in the micrometer range and allows the acquisition of the dark-field contrast. The analyzer grating is designed to match the period of the interference pattern in order to translate it into a measurable intensity modulation. In this study, we explore the influence of a sample-induced mismatch between the interference pattern and the analyzer grating on the dark-field contrast. We propose a formula for the calculation of the signal due to a period mismatch and present estimations varying periods and detector pixel size. Furthermore, numerical simulations of the X-ray wave-front demonstrate that the wave-front curvature, described by the lens-term, e.g. behind a parabolic lens or edges of a sample can change the period of the interference pattern. Our results give a concrete explanation for the formation of a dark-field contrast from object edges and thus allow a better understanding of the dark-field signal obtained with a grating interferometer.
Clinical characteristics and long-term outcomes in patients with ruptured posterior inferior cerebellar artery aneurysms: a comparative analysis (2015)

Patients with ruptured PICA aneurysms had a similar rate of radiographic vasospasm, equivalent admission Fisher grade and Hunt and Hess scores, but poorer clinical outcomes at discharge and at 1- and 3-year follow-up when compared with the rest of the BRAT SAH patients with ruptured aneurysms. The PICA's location at the medulla and the resultant high rate of lower cranial nerve dysfunction may play a role in the poor outcome for these patients. Furthermore, PICA aneurysms were more likely to be fusiform than saccular, compared with non-PICA aneurysms; the complex nature of these aneurysms may also contribute to their poorer outcome.
Syntheses of High Specific Activity 2,3- and 3,4-[3H]2-9-cis-Retinoic Acid (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSyntheses of High Specific Activity 2,3- and 3,4-[3H]2-9-cis-Retinoic AcidYoussef L. Bennani and Marcus F. BoehmCite this: J. Org. Chem. 1995, 60, 5, 1195–1200Publication Date (Print):March 1, 1995Publication History Published online1 May 2002Published inissue 1 March 1995https://pubs.acs.org/doi/10.1021/jo00110a023https://doi.org/10.1021/jo00110a023research-articleACS PublicationsRequest reuse permissionsArticle Views747Altmetric-Citations34LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
N -naphthoyl-β-naltrexamine (NNTA), a highly selective and potent activator of μ/κ-opioid heteromers (2011)

Numerous G protein-coupled receptors (GPCRs) have been shown to form heteromeric receptors in cell-based assays. Among the many heteromers reported in the opioid receptor family are μ/κ, κ/δ, and μ/δ. However, the in vivo physiological and behavioral relevance for the proposed heteromers have not yet been established. Here we report a unique example of a ligand, N-naphthoyl-β-naltrexamine (NNTA) that selectively activates heteromeric μ/κ-opioid receptors in HEK-293 cells and induces potent antinociception in mice. NNTA was an exceptionally potent agonist in cells expressing μ/κ-opioid receptors. Intriguingly, it was found to be a potent antagonist in cells expressing only μ-receptors. In the mouse tail-flick assay, intrathecal (i.t.) NNTA produced antinociception that was ~100-fold greater than by intracerebroventricular (i.c.v.) administration. The κ-antagonist, norBNI, decreased the i.t. potency, and the activity was virtually abolished in μ-opioid receptor knockout mice. No tolerance was induced i.t., but marginal tolerance (3-fold) was observed via the i.c.v. route. Moreover, NNTA produced neither significant physical dependence nor place preference in the ED50 dose range. Taken together, this work provides an important pharmacologic tool for investigating the in vivo functional relevance of heteromeric μ/κ-opioid receptors and suggests an approach to potent analgesics with fewer deleterious side effects.
Measurements of anisotropies in the Cosmic Microwave Background at small and intermediate angular scales with bolometric receivers at mm wavelengths (1997)

This thesis describes instruments and observational techniques used to make precise measurements of anisotropies in the Cosmic Microwave Background (CMB) at mm wavelengths. New developments in bolometer design and fabrication for millimeter-wave receivers are presented. Additional developments in cryogenics, readout electronics and mm-wave filters enable the construction of mm-wave receivers that take full advantage of these improvements in bolometer sensitivity. The design and performance of two millimeter-wave receivers for measuring CMB anisotropies at angular scales from a few arcminutes to ten degrees is presented. The first multifrequency array receiver for millimeter-wave astronomy, SuZIE I.5, is described. SuZIE I.5 is the second generation receiver built for the Sunyaev-Zel'dovich Infrared Experiment (SuZIE). The interaction of the CMB with hot plasma bound in clusters of galaxies, the Sunyaev-Zel'dovich (S-Z) effect, is the dominant source of CMB anisotropies at arcminute scales. Measurement of the spectrum of the Sunyaev-Zel'dovich effect at millimeter wavelengths enables the separation of contributions from the bulk motion of the cluster with respect to the rest frame of the Cosmic Microwave Background (CMB) and the random thermal motion of the electrons in the hot intracluster gas. SuZIE I.5 was used to make measurements of the spectrum of S-Z effect in the cluster, Abell 1835 (z=0.2523). These measurements are combined with the results of X-ray data in order to determine the Hubble constant (H&lt;SUB&gt;0&lt;/SUB&gt;) and the radial component of cluster peculiar velocity (v&lt;SUB&gt;r&lt;/SUB&gt;). The second receiver described is the BOOMERANG instrument, a bolometric radiometer designed to map the Cosmic Background Radiation (CMB) with 0.2&lt;SUP&gt;o&lt;/SUP&gt; resolution over a large portion of the sky. This receiver will employ new technologies in bolometers, readout electronics, cold reimaging optics, millimeter-wave filters, and cryogenics to obtain unprecedented sensitivity to CMB anisotropies combined with long integration time from a Long Duration Balloon (LDB) platform.* (Abstract shortened by UMI.) ftn*Originally published in DAI vol. 58, no. 7. Reprinted here with corrected title.
Effect of Under Floor Blockages on Data Center Performance (2006)

In a typical raised floor data center, under floor plenum supplies cold air to the computer room via perforated floor tiles. Thermal management of any data center primarily depends on air flow rates through the tiles. These tile flow rates are a function of several factors that govern the flow pattern under the raised floor. CFD analyses of an ideal raised floor can often be misleading as they may not incorporate the effect of under floor blockages such as cables, ducts, pipes and other random blockages. In this paper, the effect of under floor blockages on data center performance is discussed. A raised floor data center with 8 kW racks is considered. There are four rows of racks with six racks per row. Two air conditioning units supply chilled air to the data center through a 2 ft. deep plenum. Blockages are included in the model and are shown to have significant impact on tile flow rates and eventually the rack inlet temperatures. Parameters like blockage size and locations are investigated to come up with a set of broad guidelines which will help the facility designer to rearrange the blockages and improve the thermal performance without altering the layout or cold air supply