gebhart/patrepeval huggingface dataset:
Optical Properties of Nanocrystalline Monoclinic Y2O3 Stabilized by Grain Size and Plastic Strain Effects via High-Pressure Torsion (2017)

Yttrium oxide (yttria) with monoclinic structure exhibits unique optical properties; however, the monoclinic phase is thermodynamically stable only at pressures higher than ∼16 GPa. In this study, the effect of grain size and plastic strain on the stability of monoclinic phase is investigated by a high-pressure torsion (HPT) method. A cubic-to-monoclinic phase transition occurs at 6 GPa, which is ∼10 GPa below the theoretical transition pressure. Microstructure analysis shows that monoclinic phase forms in nanograins smaller than ∼22 nm and its fraction increases with plastic strain, while larger grains have a cubic structure. The band gap decreases and the photoluminescence features change from electric dipole to mainly magnetic dipole without significant decrease in the photoluminescence intensity after formation of the monoclinic phase. It is also suggested that monoclinic phase formation is due to the enhancement of effective internal pressure in nanograins.
Candidate tumor suppressor HYAL2 is a glycosylphosphatidylinositol (GPI)-anchored cell-surface receptor for jaagsiekte sheep retrovirus, the envelope protein of which mediates oncogenic transformation (2001)

Jaagsiekte sheep retrovirus (JSRV) can induce rapid, multifocal lung cancer, but JSRV is a simple retrovirus having no known oncogenes. Here we show that the envelope (env) gene of JSRV has the unusual property that it can induce transformation in rat fibroblasts, and thus is likely to be responsible for oncogenesis in animals. Retrovirus entry into cells is mediated by Env interaction with particular cell-surface receptors, and we have used phenotypic screening of radiation hybrid cell lines to identify the candidate lung cancer tumor suppressor HYAL2/LUCA2 as the receptor for JSRV. HYAL2 was previously described as a lysosomal hyaluronidase, but we show that HYAL2 is actually a glycosylphosphatidylinositol (GPI)-anchored cell-surface protein. Furthermore, we could not detect hyaluronidase activity associated with or secreted by cells expressing HYAL2, whereas we could easily detect such activity from cells expressing the related serum hyaluronidase HYAL1. Although the function of HYAL2 is currently unknown, other GPI-anchored proteins are involved in signal transduction, and some mediate mitogenic responses, suggesting a potential role of HYAL2 in JSRV Env-mediated oncogenesis. Lung cancer induced by JSRV closely resembles human bronchiolo-alveolar carcinoma, a disease that is increasing in frequency and now accounts for approximately 25% of all lung cancer. The finding that JSRV env is oncogenic and the identification of HYAL2 as the JSRV receptor provide tools for further investigation of the mechanism of JSRV oncogenesis and its relationship to human bronchiolo-alveolar carcinoma.
Bleomycin serum pharmacokinetics as determined by a radioimmunoassay and a microbiologic assay in a patient with compromised renal function (1977)

Serum and plasma bleomycin concentrations were determined in a patient with renal dysfunction at two creatinine clearances. The results obtained with a new radioimmunoassay and the microbiologic assay were compared. It was shown: 1) that the clearance of bleomycin from the blood is markedly retarded in severe renal dysfunction, 2) that clearance of bleomycin varies with creatinine clearance, 3) that bleomycin is probably not dialyzable, 4) that determinations on serum and plasma were equivalent, and 5) that the radioimmunoassay and microbiologic assays gave equivalent results (P less than 0.001).
Physical aspects of low power synapses based on phase change memory devices (2012)

In this work, we demonstrate how phase change memory (PCM) devices can be used to emulate biologically inspired synaptic functions in particular, potentiation and depression, important for implementing neuromorphic hardware. PCM devices with different chalcogenide materials are fabricated and characterized. The asymmetry between the potentiation and depression behaviors of the PCM is stressed. Detailed multi-physical simulations are performed to study the underlying physics of the synaptic behavior of PCM. A versatile behavioral model and a multi-level circuit-compatible model are developed for system and circuit-level neuromorphic simulations. We propose a unique low-power methodology named the 2-PCM Synapse, to use PCM devices as synapses in large scale neuromorphic systems. To show the strength of our proposed solution, we efficiently simulated fully connected feed-forward spiking neural network capable of complex visual pattern extraction from real world data.
Oily streaks and focal conic domains in L? lyotropic liquid crystals (1991)

Observations with the polarizing microscope of defects in the lyotropic Lα(SmA) phase of the quasi-ternary system cetylpiridinium chloride/hexanol/brine give evidence that oily streaks are chains of focal conic domains. The chains are stable in the vicinity of the Lα-L3 phase transition. Such a model of oily streaks was suggested long ago by G. Friedel but its existence was not confirmed unquestionably. We discuss the geometrical, topological and energetic properties of these structures and show that their stability depends on material constants, in particular, the saddle-splay rigidity $\bar{K}$, whose value can be estimated from the parameters of the oily streaks.
THE SYSTEM OF CARE FOR INJURED CHILDREN IN THE STATE OF COLORADO AND THE ROCKY MOUNTAIN REGION OF THE WESTERN UNITED STATES (2019)

This article describes the diﬀerent levels of trauma center designation in the United States and focuses on the pediatric trauma centers in the state of Colorado. These urban centers serve a large geographic area that is characterized by rugged mountains, wide open plains and rapidly changing weather patterns. Critical care ground and aeromedical transport are utilized for severely injured children and the quality of care, from initial management in the feld until discharge from the hospital, is critically evaluated by a robust trauma performance improvement (PI) program. The PI program uses audit flters, data analytics and bench-marking to continuously evaluate the network of care to optimize outcomes.
High-Performance Corrosion-Resistant Materials: Iron-Based Amorphous-Metal Thermal-Spray Coatings: SAM HPCRM Program ? FY04 Annual Report ? Rev. 0 - DARPA DSO & DOE OCRWM Co-Sponsored Advanced Materials Program (2007)

The multi-institutional High Performance Corrosion Resistant Materials (HPCRM) Team is cosponsored by the Defense Advanced Projects Agency (DARPA) Defense Science Office (DSO) and the Department of Energy (DOE) Office of Civilian Radioactive Waste Management (OCRWM), and has developed new corrosion-resistant, iron-based amorphous metals that can be applied as coatings with advanced thermal spray technology. Two compositions have corrosion resistance superior to wrought nickel-based Alloy C-22 (UNS No. N06022) in very aggressive environments, including concentrated calcium-chloride brines at elevated temperature. Corrosion costs the Department of Defense billions of dollars every year, with an immense quantity of material in various structures undergoing corrosion. For example, in addition to fluid and seawater piping, ballast tanks, and propulsions systems, approximately 345 million square feet of structure aboard naval ships and crafts require costly corrosion control measures. The use of advanced corrosion-resistant materials to prevent the continuous degradation of this massive surface area would be extremely beneficial. The Fe-based corrosion-resistant, amorphous-metal coatings under development may prove of importance for applications on ships. Such coatings could be used as an 'integral drip shield' on spent fuel containers, as well as protective coatings that could be applied over welds, thereby preventing exposure to environments that might cause stress corrosion cracking. In the future, such new high-performance iron-based materials could be substituted for more-expensive nickel-based alloys, thereby enabling a reduction in the $58-billion life cycle cost for the long-term storage of the Nation's spent nuclear fuel by tens of percent.
Lipid production in batch and fed-batch cultures of Rhodosporidium toruloidesfrom 5 and 6 carbon carbohydrates (2012)

Lipid production in R. toruloides was lower from arabinose and mixed carbohydrates than from glucose or xylose. Although high biomass and lipid production were achieved in both batch and fed-batch cultures with glucose as carbon source, for lipid production from mixtures of carbohydrates fed-batch cultivation was preferable. Constant feeding was better than intermittent feeding. The feeding strategy did not affect the relative proportion of different fatty acids in the lipid, but the presence of C5 sugars did.
Mapping a Neutralizing Epitope onto the Capsid of Adeno-Associated Virus Serotype 8 (2012)

Adeno-associated viruses (AAVs) are small single-stranded DNA viruses that can package and deliver nongenomic DNA for therapeutic gene delivery. AAV8, a liver-tropic vector, has shown great promise for the treatment of hemophilia A and B. However, as with other AAV vectors, host anti-capsid immune responses are a deterrent to therapeutic success. To characterize the antigenic structure of this vector, cryo-electron microscopy and image reconstruction (cryo-reconstruction) combined with molecular genetics, biochemistry, and in vivo approaches were used to define an antigenic epitope on the AAV8 capsid surface for a neutralizing monoclonal antibody, ADK8. Docking of the crystal structures of AAV8 and a generic Fab into the cryo-reconstruction for the AAV8-ADK8 complex identified a footprint on the prominent protrusions that flank the 3-fold axes of the icosahedrally symmetric capsid. Mutagenesis and cell-binding studies, along with in vitro and in vivo transduction assays, showed that the major ADK8 epitope is formed by an AAV variable region, VRVIII (amino acids 586 to 591 [AAV8 VP1 numbering]), which lies on the surface of the protrusions facing the 3-fold axis. This region plays a role in AAV2 and AAV8 cellular transduction. Coincidently, cell binding and trafficking assays indicate that ADK8 affects a postentry step required for successful virus trafficking to the nucleus, suggesting a probable mechanism of neutralization. This structure-directed strategy for characterizing the antigenic regions of AAVs can thus generate useful information to help re-engineer vectors that escape host neutralization and are hence more efficacious.
4-(2-[2-(2(R)-Methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile and Related 2-Aminoethylbenzofuran H3 Receptor Antagonists Potently Enhance Cognition and Attention (2004)

H(3) receptor antagonists based on a 2-aminoethylbenzofuran skeleton have been discovered, which are potent in vitro at human and rat H(3) receptors, with K(i) values of 0.1-5.8 nM. Analogues were discovered with potent (0.01-1 mg/kg) cognition and attention enhancing properties in animal models. One compound in particular, 4-(2-[2-(2(R)-methylpyrrolidin-1-yl)ethyl]benzofuran-5-yl)benzonitrile (ABT-239), combined potent and selective H(3) receptor antagonism and excellent pharmacokinetic and metabolic properties across species, with full efficacy in two behavioral models: a five-trial inhibitory avoidance acquisition model in rat pups at 0.1 mg/kg and a social recognition memory model in adult rats at 0.01 mg/kg. Furthermore, this compound did not stimulate locomotor activity and showed high selectivity for the induction of behavioral efficacy versus central nervous system based side effects. The potency and selectivity of this compound and of analogues from this class support the potential of H(3) receptor antagonists for the treatment of cognitive dysfunction.
A cooking assistant robot using intuitive onomatopoetic expressions and joint attention (2014)

A novel cooking assistance interface is proposed that guides users in the precise timing of cooking actions by means of intuitive onomatopoetic expressions associated with different cooking states and nonverbal movements on the part of a cooking assistant robot such as focusing attention through eye-gazing and gestures. The effectiveness of the scheme is demonstrated using the system to assist subjects in preparing a familiar recipe (pancakes).
Divergent viral presentation among human tumors and adjacent normal tissues (2016)

We applied a newly developed bioinformatics system called VirusScan to investigate the viral basis of 6,813 human tumors and 559 adjacent normal samples across 23 cancer types and identified 505 virus positive samples with distinctive, organ system- and cancer type-specific distributions. We found that herpes viruses (e.g., subtypes HHV4, HHV5, and HHV6) that are highly prevalent across cancers of the digestive tract showed significantly higher abundances in tumor versus adjacent normal samples, supporting their association with these cancers. We also found three HPV16-positive samples in brain lower grade glioma (LGG). Further, recurrent HBV integration at the KMT2B locus is present in three liver tumors, but absent in their matched adjacent normal samples, indicating that viral integration induced host driver genetic alterations are required on top of viral oncogene expression for initiation and progression of liver hepatocellular carcinoma. Notably, viral integrations were found in many genes, including novel recurrent HPV integrations at PTPN13 in cervical cancer. Finally, we observed a set of HHV4 and HBV variants strongly associated with ethnic groups, likely due to viral sequence evolution under environmental influences. These findings provide important new insights into viral roles of tumor initiation and progression and potential new therapeutic targets.
EPR spectroscopy of radical pairs formed by the reaction of triplet dibenzocycloheptadienylidene and fluorenylidene with organic matrices at 77 K (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTEPR spectroscopy of radical pairs formed by the reaction of triplet dibenzocycloheptadienylidene and fluorenylidene with organic matrices at 77 KRobert L. Barcus, Bradford B. Wright, Elisa. Leyva, and Matthew S. PlatzCite this: J. Phys. Chem. 1987, 91, 27, 6677–6683Publication Date (Print):December 1, 1987Publication History Published online1 May 2002Published inissue 1 December 1987https://pubs.acs.org/doi/10.1021/j100311a024https://doi.org/10.1021/j100311a024research-articleACS PublicationsRequest reuse permissionsArticle Views104Altmetric-Citations8LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Novel polymer coating for chemically absorbing CO2 for safe Li-ion battery (2020)

Gas evolution in Li-ion batteries remains a barrier for the implementation of high voltage materials in a pouch cell format; the inflation of the pouch cell is a safety issue that can cause battery failure. In particular, for manganese-based materials employed for fabricating cathodes, the dissolution of Mn<sup>2+</sup> in the electrolyte can accelerate cell degradation, and subsequently gas evolution, of which carbon dioxide (CO<sub>2</sub>) is a major component. We report on the utilization of a mixture of polymers that can chemically absorb the CO<sub>2</sub>, including the coating of aluminum foils, which serve as trapping sheets, introduced into two Ah pouch cells-based on a LiMnFePO<sub>4</sub> (cathode) and a Li<sub>4</sub>Ti<sub>5</sub>O<sub>12</sub> (anode). The pouch cells with trapping sheets experienced only an 8.0 vol% inflation (2.7 mmol CO<sub>2</sub> per gram of polymers) as opposed to the 40 vol% inflation for the reference sample. Moreover, the cells were cycled for 570 cycles at 1 C and 45 °C before reaching 80% of their retention capacity.
In situ removal of ethanol from fermentation broths. 1. Selective adsorption characteristics. (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTIn situ removal of ethanol from fermentation broths. 1. Selective adsorption characteristics.Stephen Bui, Xenophon Verykios, and Raja MutharasanCite this: Ind. Eng. Chem. Process Des. Dev. 1985, 24, 4, 1209–1213Publication Date (Print):October 1, 1985Publication History Published online1 May 2002Published inissue 1 October 1985https://pubs.acs.org/doi/10.1021/i200031a052https://doi.org/10.1021/i200031a052research-articleACS PublicationsRequest reuse permissionsArticle Views369Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
Cytotoxic and Anti-infective Sesquiterpenes Present inPlagiochila disticha(Plagiochilaceae) andAmbrosia peruviana(Asteraceae) (2009)

A pharmacological screening of the ethanol extract and fractions of two Peruvian medicinal plants, Plagiochila disticha and Ambrosia peruviana, led to the isolation and characterization of three ENT-2,3-secoaromadendrane-type sesquiterpenoids, named plagiochiline A ( 1), I ( 2), and R ( 3), as well as of two pseudoguaianolids, damsin ( 4) and confertin ( 5), which exhibited significant cytotoxic activity against a panel of human tumor cell lines. Compounds 1, 4, and 5 were also investigated for their in vitro antileishmanial, trypanocidal, and antituberculosis activity against Leishmania amazonensis axenic amastigotes and Trypanosoma cruzi trypomastigotes, as well as against MDR and sensitive strains of Mycobacterium tuberculosis, respectively.
Second-generation approach to all-organic modulators based on intrinsically polar self-assembled molecular superlattices (2003)

T. J. MarksNorthwestern UniversityDepartment of ChemistryandMaterials Research CenterEvanston, Illinois 60208-3113Abstract. Intrinsically acentric self-assembled superlattices(SASs) have been directly grown in a layer-by-layer processon the commercially available polymer Cyclotene™. Usingthe high-temperature/high-transparency ﬂuoropolyether Cy-top™ as a cladding layer, the SAS ﬁlms have been used tosuccessfully fabricate traveling-wave electro-optic (EO)modulators, demonstrating a straightforward approach to-ward ‘‘all-organic’’ modulators.
Photometric Light Sources (1999)

Abstract The sections in this article are Blackbody Radiation Luminescence Measurement of Light Sources Colorimetry Visible Light Sources Infrared and Ultraviolet Light Sources Sources of X Rays
Inflammation and neurological adverse drugs reactions: a case of long lasting impaired consciousness after oxatomide administration in a patient with gastroenteritis (2012)

Abstract Oxatomide at therapeutic doses generates occasionally drowsiness in children. When administered at toxic doses, however oxatomide may induce long lasting impaired consciousness. We now report a case of severe long lasting impaired consciousness induced by therapeutic doses of oxatomide occurring in a child affected by acute gastroenteritis. The clinical symptoms, the pharmacogenetic tests of polymorphisms in cytochrome P450 metabolizing enzymes (CYPs) and the clinical and laboratory analyses indicate that the enhanced drug sedative effect is likely due to an acute, yet mild, inflammatory state of the patient. These findings highlight the importance of assessing common, not serious inflammatory states when oxatomide is prescribed in paediatric patients.
Birefringent Polarization Ray Tracing (1993)

The fundamental tool used for design and analysis of optical systems is geometric ray tracing. In isotropic, homogeneous, non-optically active media the procedure is simple -- rays travel in straight lines except at interfaces, where reflection and refraction occur.
Transfer Learning in Brain-Computer Interfaces with Adversarial Variational Autoencoders (2018)

We introduce adversarial neural networks for representation learning as a novel approach to transfer learning in brain-computer interfaces (BCIs). The proposed approach aims to learn subject-invariant representations by simultaneously training a conditional variational autoencoder (cVAE) and an adversarial network. We use shallow convolutional architectures to realize the cVAE, and the learned encoder is transferred to extract subject-invariant features from unseen BCI users' data for decoding. We demonstrate a proof-of-concept of our approach based on analyses of electroencephalographic (EEG) data recorded during a motor imagery BCI experiment.
From sonic Pi to overtone (2013)

Domain Specific and Functional languages provide an excellent linguistic context for exploring new forms of music notation -- not just for formalising compositions but also for live interaction workflows. This experience report describes two novel live coding systems that employ code execution to modify live sounds and music. The first of these systems, Sonic Pi, aims at teaching core computing notions to school students using live-coded music as a means of stimulating and maintaining student engagement. We describe how an emphasis on a functional style improves the ease in which core computer science concepts can be communicated to students. Secondly we describe Overtone, a functional language and live coding environment aimed towards mprofessional electronic musicians. We describe how Overtone's abstractions and architecture strongly benefit from a functional-oriented implementation. Both Sonic Pi and Overtone are freely available open-source platforms.
Development and first clinical use of a novel anatomical and biomechanical testing platform for scoliosis (2019)

A novel synthetic spine model for corrective scoliosis procedures is presented, along with early clinical experience using this model as a surgical planning platform. This model has tremendous potential not only as a surgical planning platform but also as an adjunct to patient consent, surgical education, and biomechanical research.