gebhart/patrepeval huggingface dataset:
Dark current measurement of Type-II superlattice infrared focal plane array detector (2014)

We report the result of a dark current measurement of a Type-II superlattice (T2SL) infrared focal plane array (FPA), which consists of a 6 &mu;m cutoff T2SL detector array and the readout integration circuit (ROIC) ISC0903 of FLIR Systems. In order to measure the dark current of the FPA, we obtained images with different exposure times in a fully closed cold shield of 77 K. Using the temporal change rate of the output and considering the charge conversion efficiency of the ROIC, we obtained a dark current density with an average value of 4 × 10<sup>-5</sup> A/cm<sup>2</sup> at a bias of -100 mV. We also compare the result of the FPA dark current measurement with that of a test element group (TEG), which was a single pixel detector, fabricated by the same process as the FPA. The dark current density of the TEG was 3 × 10<sup>-6</sup> A/cm<sup>2</sup> at a bias of -100 mV, lower than that of the FPA. We discuss the discrepancy between the dark current densities of the FPA and the TEG.
The Natural History of Lone Atrial Flutter (2004)

Lone atrial flutter has a stroke risk at least as high as lone atrial fibrillation and carries a higher risk for subsequent development of atrial fibrillation than in the general population. Anticoagulation should be considered for all patients with atrial flutter who are older than 65 years of age.
Seq-2-Seq based Refinement of ASR Output for Spoken Name Capture (2022)

Person name capture from human speech is a difficult task in human-machine conversations.In this paper, we propose a novel approach to capture the person names from the caller utterances in response to the prompt "say and spell your first/last name".Inspired from work on spell correction, disfluency removal and text normalization, we propose a lightweight Seq-2-Seq system which generates a name spell from a varying user input.Our proposed method outperforms the strong baseline which is based on LM-driven rule-based approach.
Bandwidth-Reconfigurable Liquid-Metal Tunable Bandpass Filter (2021)

A bandwidth reconfigurable substrate integrated waveguide (SIW) filter utilizing liquid metal is presented. The design is implemented with two continuously tunable cavity resonators that are coupled together by a novel inductive iris design. For bandwidth control, five continuously tunable liquid metal posts are located in the inductive iris. Each via can be capacitively loaded with liquid metal to increase the inter-resonator coupling or short-circuited to reduce the effective iris width. The combination of capacitive loading and inductive shorting allows for a wide range of realizable bandwidths over the frequency tuning range of the device. Filter samples were fabricated, and the iris tuning mechanism was validated by realizing a 541 MHz Butterworth response and a 278 MHz Butterworth response by tuning the liquid metal in the five iris tuning posts.
Differential Effects of Nitrogen Substitution in 5‐ and 6‐Membered Aromatic Motifs (2020)

Invited for the cover of this issue is the group of Ronald T. Raines at the Massachusetts Institute of Technology. The image depicts the consequence of replacing carbon with nitrogen in aromatic systems, represented by Kekulé's allegorical snake. Read the full text of the article at 10.1002/chem.202000825.
Increasing Minimally Invasive Hysterectomy (2011)

A change from majority abdominal hysterectomy to minimally invasive hysterectomy was accompanied by a significant decrease in procedure-related complications without an increase in total mean costs.
Comparative study of 2-DOF micromirrors for precision light manipulation (2001)

Many industry experts predict that the future of fiber optic telecommunications depends on the development of all-optical components for switching of photonic signals from fiber to fiber throughout the networks. MEMS is a promising technology for providing all-optical switching at high speeds with significant cost reductions. This paper reports on the the analysis of two designs for 2-DOF electrostatically actuated MEMS micromirrors for precision controllable large optical switching arrays. The behavior of the micromirror designs is predicted by coupled-field electrostatic and modal analysis using a finite element analysis (FEA) multi-physics modeling software. The analysis indicates that the commonly used gimbal type mirror design experiences electrostatic interference and would therefore be difficult to precisely control for 2-DOF motion. We propose a new design approach which preserves 2-DOF actuation while minimizing electrostatic interference between the drive electrodes and the mirror. Instead of using two torsional axes, we use one actuator which combines torsional and flexural DOFs. A comparative analysis of the conventional gimbal design and the one proposed in this paper is performed.
Adventitial lymphatic capillary expansion impacts on plaque T cell accumulation in atherosclerosis (2017)

During plaque progression, inflammatory cells progressively accumulate in the adventitia, paralleled by an increased presence of leaky vasa vasorum. We here show that next to vasa vasorum, also the adventitial lymphatic capillary bed is expanding during plaque development in humans and mouse models of atherosclerosis. Furthermore, we investigated the role of lymphatics in atherosclerosis progression. Dissection of plaque draining lymph node and lymphatic vessel in atherosclerotic ApoE<sup>-/-</sup> mice aggravated plaque formation, which was accompanied by increased intimal and adventitial CD3<sup>+</sup> T cell numbers. Likewise, inhibition of VEGF-C/D dependent lymphangiogenesis by AAV aided gene transfer of hVEGFR3-Ig fusion protein resulted in CD3<sup>+</sup> T cell enrichment in plaque intima and adventitia. hVEGFR3-Ig gene transfer did not compromise adventitial lymphatic density, pointing to VEGF-C/D independent lymphangiogenesis. We were able to identify the CXCL12/CXCR4 axis, which has previously been shown to indirectly activate VEGFR3, as a likely pathway, in that its focal silencing attenuated lymphangiogenesis and augmented T cell presence. Taken together, our study not only shows profound, partly CXCL12/CXCR4 mediated, expansion of lymph capillaries in the adventitia of atherosclerotic plaque in humans and mice, but also is the first to attribute an important role of lymphatics in plaque T cell accumulation and development.
A planar, via-less zeroth-order antenna for wearable electrocardiography (2014)

Summary form only given. Wireless medical telemetry service is one of the fastest emerging technologies in healthcare industries worldwide. In addition, the proliferation of smartphones is currently serving as a catalyst to the increasing growth in this sector. Based on a secure, close-range wireless body area network (WBAN) which relays the patient's physiological information to a nearby cellular device, a real-time monitoring system for those who require a relatively close medical attention can be realized. Among the physiological parameters, the pulse and the respiration rates are important indicators for wide range of healthcare applications ranging from recreational sports to wireless medical monitoring. Despite the significant advantages, the technical challenges of devising a wearable, sturdy health monitoring device with a reliable radio must be fully resolved. When operating at the industrial, medical and scientific (ISM) radio band, the antenna is expected to be one of the largest components within the device. It is imperative for the antenna to remain low-profile and yet be capable of exhibiting efficient radiation characteristics albeit the detrimental effects of the user's body on the antenna matching and radiation. In this paper, a planar, zeroth-order resonance (ZOR) antenna is proposed for a wearable and detachable electrocardiography (ECG) sensor device. The profile of the proposed antenna topology is minimized using two distinctive techniques: 1.The elimination of vias unlike the conventional mushroom-shaped ZOR topologies. 2. Modeling of the radiator, series capacitance, shunt inductance and the ground on a single printed circuit board (PCB) layer. An air-bridge employed co-planar waveguide (CPW) structure is designed as the antenna feed network between the antenna element and the in-house low power 2.4 GHz RFIC. The overall dimension of the planar ZOR antenna is 15 mm × 9.6 mm × 3 mm when fabricated using a flexible PCB (İr = 2.2, tan = 0.02). The antenna is placed above the main board PCB of the ECG device and subsequently covered with flexible polycarbonate chassis. The radiation properties of the ZOR antenna within the assembled ECG device is studied by placing the device on the surface of the human body model with electrical properties as follows: Skin (ı=1.46 S/m, h=0.5mm), Body fat (ı=0.27 S/m, h=10.5mm), Muscle (ı=1.74 S/m, h=20mm) where h is denoted as the thickness. Simulation and measurements confirm a -10 dB S11 bandwidth of more than 80 MHz and a radiation efficiency of more than 30% in the presence of the human body. Overall, the ZOR antenna is confirmed to feature more than 3.5 m enhanced communication coverage and more than 20% higher antenna radiation efficiency in comparison to that using conventional chip antennas and monopoles under identical measurement conditions.
Safety and Efficacy of Electroconvulsive Therapy for Depression in the Presence of Deep Brain Stimulation in Obsessive-Compulsive Disorder (2016)

Article AbstractBecause this piece does not have an abstract, we have provided for your benefit the first 3 sentences of the full text.To the Editor: In an important recent article, Fontenelle et al reviewed published reports of electroconvulsive therapy (ECT) in patients with obsessive-compulsive disorder (OCD), finding inconclusive evidence for efficacy of ECT in OCD despite clinical improvement in about 60% of published cases. ECT remains the most effective treatment for severe depression and can be lifesaving. Because OCD is often comorbid with severe depression, ECT remains an important treatment consideration in this patient population.
MECOM copy number alterations identify a new group of myeloid neoplasms with a poor prognosis (2022)

Abstract Objective Myeloid neoplasms (MNs) harboring inv(3)(q21q26)/t(3;3)(q21;q26) or MECOM gene rearrangements as identified by fluorescence in situ hybridization (FISH) are known to carry a poor prognosis. The objective of this study is to assess prognostic impact of MNs with copy number alterations (CNA) in MECOM as compared to MNs with inv(3)/t(3;3) or MECOM rearrangements. We present those initial comparative results and secondarily assess whether genetic mutations that confer a worse clinical outcome are also associated with MNs with MECOM CNA. Methods A retrospective review of electronic pathology records was performed at Beth Israel Deaconess Medical Center. All MNs from 2016 – current with MECOM FISH (Abbott Molecular, Abbott Park, IL) confirmed analyses were extracted. Other additional items extracted included karyotype and next-generation sequencing (NGS) results of a 65 gene myeloid panel (SmartGenomics Myeloid Profile, PathGroup, Nashville, TN). Kaplan-Meier and ANOVA were performed using GraphPad Prism (San Diego, CA). Results A total of 307 cases were identified in which MECOM FISH was performed. Exclusion of cases lacking inv(3)/t(3;3), MECOM rearrangement, or MECOM CNA provided an initial study cohort of 20 cases. 5 cases had MECOM rearrangement with inv(3)/t(3;3), 7 had MECOM rearrangement without inv(3)/t(3;3), and 8 had MECOM CNA. 13 of 20 cases had a complex karyotype, 13 of 20 cases had a monosomal karyotype, 10 of 20 cases had both a complex and monosomal karyotype. Of the 20 cases in which MECOM FISH demonstrated inv(3)/t(3;3), MECOM rearrangement, or CNA, NGS was performed on 16 cases. Genes known to be associated with a significant negative overall survival (OS) include ASXL1, EZH2, IDH2, KRAS, NRAS, RAD21, RUNX1, SRSF2, STAG2, TP53 with single and multiple mutations found in 9 of 20 cases. Kaplan-Meier analysis revealed no significant difference in OS among the three MECOM aberration groupings (Log-rank test; p=0.77). Single factor ANOVA analysis revealed enrichment for high risk gene mutations in MECOM CNA (p=0.04) and TP53 mutations (p=0.04) when compared to MNs with MECOM rearrangements. Summary Our analysis of MNs with MECOM aberrations by FISH reveal that MECOM with CNA display similarly poor overall survival as MNs with inv(3)/t(3;3) and MECOM rearrangements. Additionally, the MECOM CNA group was enriched for high risk gene mutations and TP53 as compared to inv(3)/t(3;3) and MECOM rearrangement groups. Overall, the initial results of this study reveal a new group of MNs harboring MECOM CNA that confer a poor prognosis and high risk mutational profile.
Joint Transmission for Space Time Block Coded TD-SCDMA (2006)

Since Time Division Synchronous Code Division Multiple Access (TD-SCDMA) technology, one of the Time Division Duplex (TDD) standards modes of 3rd Generation Partnership Project (3GPP), adopted a lower spreading rate, 1.28 MChip/sec, it is usually referred to Low Chip Rate Time Division CDMA (LCR-TD- CDMA). Therefore its multipath diversity is not large enough due to fewer independent paths. Furthermore, it suffers from multi-user access interference (MAI) as other CDMA systems, where the influence of MAI is not small due to its small spreading factor. Our proposed solution overcomes all these shortcomings of TD-SCDMA technology. We propose an implementation of Space Time Block Coding (STBC) to introduce diversity to combat low multi-path diversity character of TD-SCDMA. We further incorporate joint transmission (JT) technique to remove MAI, and thereby improve system performance. The introduction of JT at the base station (BS) side also helps to reduce the complexity of the mobile station (MS). We use a combination of analytical and simulation methods to evaluate the performance of the proposed system. The results show significant improvement for the proposed system.
LETTER TO THE EDITOR (1998)

Journal Article LETTER TO THE EDITOR Get access Isaac Ginsburg, MSc, PhD Isaac Ginsburg, MSc, PhD The Hebrew University Hadassah School of Dental Medicine Department of Oral Biology Jerusalem, Israel Search for other works by this author on: Oxford Academic Google Scholar Journal of Leukocyte Biology, Volume 63, Issue 4, April 1998, Pages 518–519, https://doi.org/10.1002/jlb.63.4.518 Published: 01 April 1998
Effect of Sn for Ferritic Stainless Steels on Corrosion Resistance in Sulfuric Acid Solutions (2017)

フェライト系ステンレス鋼の硫酸溶液中における耐食性に及ぼすSnの影響を調査するために浸漬試験，分極曲線測定および電気化学インピーダンス測定を行った．鋼中へのSn添加および溶液へのSn2＋イオン添加は，H2SO4水溶液中における腐食速度を低減させた．H2SO4水溶液中において，鋼中へのSn添加は腐食電位近傍のアノード溶解を抑制した．また，溶液へのSn2＋イオン添加はアノード反応とカソード反応を抑制した．鋼中へのSn添加は，pH 0.5～2のNa2SO4水溶液中において大きなアノード溶解抑制効果を有し，その電位域はSn2＋イオンの熱力学的安定域にあった．フェライト系ステンレス鋼中のSnは，Sn2＋イオンとして硫酸溶液中に溶出し，Sn2＋イオンに由来するSn化学種が表面に吸着して活性溶解を抑制していると考えられた．
A Review of Gene Therapy in Canine and Feline Models of Lysosomal Storage Disorders (2015)

Lysosomal storage disorders (LSDs) are inherited diseases that result from the intracellular accumulation of incompletely degraded macromolecules. The majority of LSDs affect both the peripheral and central nervous systems and are not effectively treated by enzyme replacement therapy, substrate reduction therapy, or bone marrow transplantation. Advances in adeno-associated virus and retroviral vector development over the past decade have resurged gene therapy as a promising therapeutic intervention for these monogenic diseases. Animal models of LSDs provide a necessary intermediate to optimize gene therapy protocols and assess the safety and efficacy of treatment prior to initiating human clinical trials. Numerous LSDs are naturally occurring in large animal models and closely reiterate the lesions, biochemical defect, and clinical phenotype observed in human patients, and whose lifetime is sufficiently long to assess the effect on symptoms that develop later in life. Herein, we review that gene therapy in large animal models (dogs and cats) of LSDs improved many manifestations of disease, and may be used in patients in the near future.
Tracking and threat assessment for automotive collision avoidance (2007)

This thesis is concerned with automotive active safety, and a central theme is a new safety function called Emergency Lane Assist (ELA). Automotive safety is often categorised into passive and active safety, where passive safety is concerned with reducing the effects of accidents and active safety aims at avoiding them. ELA detects lane departure manoeuvres that are likely to result in a collision and prevents them by applying a steering wheel torque. The ELA concept is based on traffic accident statistics, i.e., it is designed to give maximum safety based on information about real life traffic accidents. The ELA function puts tough requirements on the accuracy of the information from the sensors, in particular the road shape and the position of surrounding objects, and on robust threat assessment. Several signal processing methods have been developed and evaluated in order to improve the accuracy of the sensor information, and these improvements are also analysed in how they relate to the ELA requirements. Different threat assessment methods are also studied, and a common element in both the signal processing and the threat assessment is that they are based on driver behaviour models, i.e., they utilise the fact that depending on the traffic situation, drivers are more likely to behave in certain ways than others. Most of the methods are general and can be, and hopefully also will be, applied also in other safety systems, in particular when a complete picture of the vehicle surroundings is considered, including information about road and lane shape together with the position of vehicles and infrastructure. All methods in the thesis have been evaluated on authentic sensor data from actual and relevant traffic environments.
Experimental and numerical investigation of standing-wave thermoacoustic instability under transcritical temperature conditions (2021)

This manuscript describes an experimental and numerical investigation of transcritical thermoacoustic instability in a standing-wave setup using the refrigerant octafluoropropane (R-218) as the working fluid. Thermoacoustic instability is excited by two microtube heat exchangers separated by a vacuum-jacketed microtube stack. R-218 is allowed to flow axially through the microtubes into a closed resonator while heating and cooling fluids flow radially over the microtubes to create a temperature gradient. The fluid achieved pressure amplitudes up to 669 kPa (97 psi) at a temperature difference ΔT=T<sub>hot</sub>-T<sub>cold</sub> of 150 K and a base pressure, P<sub>0</sub>, of 1.3 times the critical pressure (3.43 MPa). The high pressure amplitudes obtained are attributed to the strong density variations near the critical point of the working fluid. The thermoacoustic response was characterized in a set of parametric studies in which ΔT, base pressure, and resonator length were varied. A modeling approach based on linearized Navier-Stokes equations reproduces the experimental results with fair agreement. This work demonstrates promising application of transcritical working fluids to thermoacoustic engines as devices for energy extraction and waste heat removal.
Cloning of a novel pilin‐like gene from Bordetella pertussis: homology to the fim2 gene (1988)

A search for pilin genes in a Bordetella pertussis (Bp) genomic library has led to the identification of several clones which hybridize to synthetic oligonucleotides with sequences derived from amino acid sequences of Bp fimbrial subunits. One of these clones (corresponding to a gene we have named fimX) contains an open reading frame encoding a protein with a molecular weight of about 20 kD and a sequence similar but not identical to the fimbrial subunit fim2 and to other fimbrial protein sequences. In this communication we present the cloning and nucleotide sequence of the fimX gene and its homology to the fim2 gene. A genomic analysis on the positional relationship between the two genes is also presented.
P1-188 Analysis of questionnaire surveys on mothers' anxieties about child-rearing in rural areas of Japan (2011)

<h3>Background</h3> In Japan, as society changes, becoming ever more isolated and with rises in nuclear families, mothers are increasingly concerned and uneasy about child care. These changes have also coincided with a significant decrease in birth rates. The government took out the “indicator of support plan for the 21st century” in 2001. So, each prefecture had to draw up a concrete plan by 2005. <h3>Purpose</h3> The purpose of study was to explore factors affecting mothers9 anxieties and to evaluate effects of a child care support plan. <h3>Sample and Statistical Analysis</h3> The questionnaire surveys were conducted with 1000 mothers, selected randomly, in 2002 and 2008. Mothers9 anxiety was measured using feelings of loneliness, confusion about child-rearing and lack of standards as the children9s development process. These were analysed using “ordered categorical logistic regression”. The explanatory variables were mother9s age, child9s age and child-rearing methods. <h3>Results</h3> ‘Feelings of loneliness9 was negatively correlated with a child9s age (p value=0.07) and a maternal age (p value=0.044). Mothers9 mental instability and a lack of families9 cooperation significantly related with ‘feelings of loneliness9 (p values=0.000, 0.000, respectively). “Feelings of loneliness” and “confusion about child-rearing” in 2008 (after implementation of the child care support plan) were reduced compared with those in 2002 (p values=0.069, 0.065, respectively). <h3>Conclusions</h3> The introduction of a child care support plan including opportunities for counselling, friendship and activities increased family co-operation and more social interaction for both mother and child. The research shows these can be effective methods in reducing mothers9 anxieties.
ChemInform Abstract: Synthesis of a Hybrid Analogue (I) of the Acetylcholinesterase Inhibitors Huperzine A and Huperzine B. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Self-Administered Drug Compliance in Nepali Leprosy Patients (1989)

The self administration of dapsone by Nepali leprosy patients receiving multidrug therapy was assessed by a colorimetric and a filter paper spot test. Overall 45 out of 337 (13.3%) patients were found to be non-compliant. The relation of non-compliance to sex, age, leprosy classification, therapy type and length of therapy was investigated. The spot test was compared with the colorimetric assay and found to have a relative sensitivity of 99.3% and specificity of 95.4%. Follow up of patients was successful in that two-thirds of non-compliant patients were compliant on their follow-up test.