gebhart/patrepeval huggingface dataset:
Transient ferracyclobutanes during protonation of .eta.3-homoallyliron(0) complexes (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTransient ferracyclobutanes during protonation of .eta.3-homoallyliron(0) complexesMartin F. Semmelhack and Hanh T. M. LeCite this: J. Am. Chem. Soc. 1985, 107, 5, 1455–1457Publication Date (Print):March 1, 1985Publication History Published online1 May 2002Published inissue 1 March 1985https://pubs.acs.org/doi/10.1021/ja00291a082https://doi.org/10.1021/ja00291a082research-articleACS PublicationsRequest reuse permissionsArticle Views92Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Design of waveguide-integrated graphene devices for photonic gas sensing (2016)

We present waveguide-integrated graphene devices for photonic gas sensing. In a gas environment, graphene's conductivity is changed by adsorbed gas molecules which serve as charge-carrier donors or acceptors. To accurately probe gas-induced variations in the graphene's conductivity, we optimize the graphene's Fermi level and spectral region. Then, we propose graphene-on-silicon and graphene-on-germanium suspended membrane slot waveguides in which propagating light in the waveguide has a strong interaction with the top graphene layer. The gas concentration can be calculated by measuring the spectrum of the optical reflection from the waveguide Bragg grating. The maximum sensitivity of the waveguide-integrated gas sensor can reach one part per million for sensing gaseous nitrogen dioxide. Its sensitivity is about 20 times higher than that of the graphene-covered microfiber sensor and is comparable with that of a graphene plasmonic sensor. The fabrication of the proposed graphene device is CMOS compatible. Our results pave a way for chip-integrated sensitive photonic gas sensors.
Study of ultramicroporous carbons by high-pressure sorption. Part 2.—Nitrogen diffusion kinetics (1989)

Sorption–desorption kinetics for nitrogen in the as-received TCM 128 ultramicroporous carbon fibre are reported at 35 °C over a wide range of pressures. The nitrogen sorption kinetics at low pressures follow the Fickian model. As the pressure increases, the deviations from the model become more pronounced, and at sufficiently high pressure a sigmoid kinetic response shape is observed which is indicative of a non-Fickian diffusion process. An additional timescale must be active to account for the non-Fickian transport behaviour. This second timescale process may correspond to adsorbate surface rearrangements leading to locally time-dependent clearing of constrictions at a rate with a characteristic kinetic constant. The nitrogen desorption kinetics are found to be less affected by the non-Fickian transport, thus leading to higher apparent diffusion coefficients for the same average pressures. At high pressures and very long sorption times, slow protracted uptake becomes apparent into restricted regions. The kinetics for this process can be described by a barrier model and are sufficiently slow to allow treatment independent of the processes occurring in the more open pore system.
Supplementary Figure 2 from Integrative Radiogenomic Profiling of Squamous Cell Lung Cancer (2023)

&lt;p&gt;PDF file, 138K, High-throughput profiling of survival following exposure to �-radiation.&lt;/p&gt;
Diffusion of zirconium on the surface of Schottky electron sources (2021)

The current study investigates the diffusion of a Zr–O complex on a W substrate, which is one of the surface components of the Schottky electron source. To enable the thermal diffusion of Zr atoms with the assistance of oxygen, the source was heated to approximately 1800 K; this enabled the Zr–O complex to reach the electron emission area at the source apex, which was several hundred micrometers away from the Zr reservoir. At such a high temperature, the evaporation rate of surface components also increased, making it more difficult for the atoms to diffuse farther. To better understand the mechanisms underlying diffusion and evaporation, the amount of Zr on the surface was estimated using Auger electron spectroscopy. The surface coverage of the Zr–O complex was found to be almost constant up to 600 μm without any significant loss. Furthermore, the diffusion of the Zr–O complex was found to be more dominant than evaporation, resulting in coverage saturation. However, when coverage of the Zr–O complex decreased, the observed trends changed drastically, which suggests that the balance of diffusion and evaporation cannot be described by a simple material balance equation. Additionally, the range with a fully covered area of the Zr–O complex became narrower at temperatures higher than 1900 K. These features, however, varied depending on the vacuum level surrounding the sample. Based on these findings, the diffusion and evaporation model of Zr and O on the surface of the Schottky electron source is proposed.
Power-Controlled Feedback and Training for Two-Way MIMO Channels (2010)

Most communication systems use some form of feedback, often related to channel state information. The common models used in analyses either assume perfect channel state information at the receiver and/or noiseless state feedback links. However, in practical systems, neither is the channel estimate known perfectly at the receiver and nor is the feedback link perfect. In this paper, we study the achievable diversity multiplexing tradeoff using i.i.d. Gaussian codebooks, considering the errors in training the receiver and the errors in the feedback link for frequency division duplex (FDD) systems, where the forward and the feedback are independent multiple input multiple output (MIMO) channels. Our key result is that the maximum diversity order with one-bit of feedback information is identical to systems with more feedback bits. Thus, asymptotically in <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">SNR</i> , more than one bit of feedback does not improve the system performance at constant rates. Furthermore, the one-bit diversity-multiplexing performance is identical to the system which has perfect channel state information at the receiver along with noiseless feedback link. This achievability uses novel concepts of power controlled feedback and training, which naturally surface when we consider imperfect channel estimation and noisy feedback links. In the process of evaluating the proposed training and feedback protocols, we find an asymptotic expression for the joint probability of the <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">SNR</i> exponents of eigenvalues of the actual channel and the estimated channel which may be of independent interest.
Structure of transfer RNA by carbon NMR: resolution of single carbon resonances from13C-enriched, purified species (1980)

Methyl carbon-13 NMR spectra of purified tRNA species are presented for the first time. In addition, these spectra of tRNA species specific for phenylalanine, tyrosine, and cysteine exhibited the first resolution of single methyl carbon resonances. Carbon-13 enriched methyl groups of ribothymidine (T) and 7-methylguanosine (m7G) and the methylthio group of 2-methylthio-N6-(delta2-isopentenyl) adenosine (ms2i6A) were resolved. The T methyl signal of tRNAPhe shifted from 12.3 ppm at 45 degrees in the absence of added Mg2+ to 11.1 ppm at 30 degrees in the presence of 10mM MgCl2. The same change in conditions led to a 0.4 ppm shift of the m7G methyl signal in the opposite direction. The relative ease in obtainment of single carbon resonances of purified tRNA species, and display of the sensitivity of their chemical shifts to changes in local structure, are requisite criteria for 13C-NMR to be a useful technique in probing tRNA conformation and its changes during interaction with proteins and other nucleic acids.
Developmental Expression of Creatine Kinase Isoenzymes in Chicken Growth Cartilage (1999)

We have shown previously that creatine kinase (CK) activity is required for normal development and mineralization of chicken growth cartilage and that expression of the cytosolic isoforms of CK is related to the biosynthetic and energy status of the chondrocyte. In this study, we have characterized changes in isoenzyme activity and mRNA levels of CK (muscle-specific CK, M-CK; brain-type CK, B-CK; and mitochondrial CK subunits, MiaCK and MibCK) in the growth plate in situ and in chondrocyte culture systems that model the development/maturation program of the cartilage. The in vitro culture systems analyzed were as follows: tibial chondrocytes, which undergo hypertrophy; embryonic cephalic and caudal sternal chondrocytes, which differ from each other in their mineralization response to retinoic acid; and long-term micromass cultures of embryonic limb mesenchymal cells, which recapitulate the chondrocyte differentiation program. In all systems analyzed, B-CK was found to be the predominant isoform. In the growth plate, B-CK expression was highest in the most calcified regions, and M-CK was less abundant than B-CK in all regions of the growth plate. In tibial chondrocytes, an increase in B-CK expression was seen when the cells became hypertrophic. Expression of B-CK increased slightly over 15 days in mineralizing, retinoic acid-treated cephalic chondrocytes, but it decreased in nonmineralizing caudal chondrocytes, while there was little expression of M-CK. Interestingly, in limb mesenchyme cultures, significant M-CK expression was detected during chondrogenesis (days 2-7), whereas hypertrophic cells expressed only B-CK. Finally, expression of MiaCK and MibCK was low both in situ and in vitro. These observations suggest that the CK genes are differentially regulated during cartilage development and maturation and that an increase in CK expression is important in initiating chondrocyte maturation.
Tailoring graphene-supported Ru nanoparticles by functionalization with pyrene-tagged N-heterocyclic carbenes (2021)

Controlling the reactivity and stability of graphene-supported Ru NPs by modifying their surface with pyrene-tagged N -heterocyclic carbene ligands.
Optical data transmission ASICs for the high-luminosity LHC (HL-LHC) experiments (2014)

We present the design and test results of two optical data transmission ASICs for the High-Luminosity LHC (HL-LHC) experiments. These ASICs include a two-channel serializer (LOCs2) and a single-channel Vertical Cavity Surface Emitting Laser (VCSEL) driver (LOCld1V2). Both ASICs are fabricated in a commercial 0.25-um Silicon-on-Sapphire (SoS) CMOS technology and operate at a data rate up to 8 Gbps per channel. The power consumption of LOCs2 and LOCld1V2 are 1.25 W and 0.27 W at 8-Gbps data rate, respectively. LOCld1V2 has been verified meeting the radiation-tolerance requirements for HL-LHC experiments.
ChemInform Abstract: Bryostatins: The Asymmetric Synthesis of the C17‐C27 Fragment. (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Generation of highly circularly polarized light from uniform InAs/GaAs quantum dots (2007)

Abstract Highly circularly polarized light is generated from highly uniform InAs/GaAs quantum dots. These quantum dots allowed us to observe the spin dynamics at each energy state selectively without disturbing the inhomogeneous broadening. Time‐resolved spin‐dependent photoluminescence measurements show that the spin polarization at the second excited state reaches a maximum of 45% at 10 K, and that the spin polarization is greater at higher‐energy states. This large spin polarization is explained by the spin Pauli blocking effect. (© 2008 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)
An exact solution of torsional quartz crystal resonators of free-free bar-type. (1996)

An exact solution of a partial differential equation including elastic compliance constant S56', with respect to stress function Ψ has been found for torsional modes of vibration of an arbitrary (singly, doubly, triply) rotated quartz crystal beam with a pair of parallel, free edges. The solution is obtained by relaxing the condition that the edge planes are perpendicular to the main faces of the beam. That is, the edges are off perpendicular by the angle θ=arctan (-S56'/S55'). The exact solution can reduce the difference of the calculatedand measured values of frequency constant for a thickness-to-width ratio. Also, a comparatively large-inclination of the edge cuts is required to reduce the unwanted, complicated mode shapes to simple ones.
Purification and characterization of a novel growth factor from human breast cancer cells (1992)

We have purified and characterized a novel 30-kDa glycoprotein (gp30) with TGF alpha-like properties secreted from the estrogen receptor negative breast cancer cell line MDA-MB-231. This factor was immunoprecipitated by an anti-TGF alpha polyclonal antibody and also had TGF alpha-like biological activity, as assayed by EGF radioreceptor assay and anchorage-independent assays. In addition, the novel growth factor stimulated phosphorylation of the EGF receptor and erbB-2 receptor. However, the novel growth factor, unlike EGF and TGF alpha, bound to heparin-Sepharose. Purification of gp30 was obtained to apparent homogeneity by heparin affinity chromatography and subsequent reversed-phase chromatography. Tunicamycin treatment in vivo or N-glycanase deglycosylation in vitro revealed a putative precursor of approximately 22 kDa molecular mass in contrast to the "normal" 16-kDa precursor species for TGF alpha. In vitro translation of total mRNA from MDA-MB-231 cells confirmed the size of the putative precursor. Biochemical characterization of gp30 was begun by V8 protease digestion of the deglycosylated polypeptide and the translated products. Peptide mapping of V8-digested, immunoprecipitated material suggests that the amino acid sequence of this unique protein is distinct from mature TGF alpha and not the result of a posttranslational modification of the precursor. We conclude that this TGF alpha-like (gp30) polypeptide is a novel growth factor with agonistic activity for both EGF and erbB-2 receptors.
Synthesis and Duplex‐Stabilizing Properties of Fluorinated N‐Methanocarbathymidine Analogues Locked in the C3′‐endo Conformation (2014)

Abstract The efficient synthesis, antiviral activity, and duplex‐stabilizing properties of both isomers of the 2′‐fluoro analogue of Northern methanocarbathymidine (N‐MCT), 2 and 3 , are reported. We show that 2′‐F incorporation on the N‐MCT scaffold has a strong stabilizing effect on duplex thermal stability.
New Photoluminescent Display Devices (1999)

Liquid crystal displays represent the dominant flat panel display technology, despite their limitations in brightness and efficiency originating from the use of absorbing polarizers and color filters. This paper reviews novel concepts of photoluminescent liquid crystal displays that employ photoluminescent polarizers. These polarizers exhibit highly anisotropic absorption and / or emission and efficiently combine two separate features: the polarization of light and the generation of bright color. A new photophysical effect - polarizing energy transfer - can be used to drive the efficiency of these elements to the theoretical limit: it enables to produce photoluminescent polarizers which optimally harvest incident light by isotropic absorption but emit the absorbed energy in highly linearly polarized fashion. Experiments suggest that the novel concepts can simplify device design and substantially increase device brightness, contrast, and efficiency.
αv integrins on mesenchymal cells regulate skeletal and cardiac muscle fibrosis (2017)

Mesenchymal cells expressing platelet-derived growth factor receptor beta (PDGFRβ) are known to be important in fibrosis of organs such as the liver and kidney. Here we show that PDGFRβ<sup>+</sup> cells contribute to skeletal muscle and cardiac fibrosis via a mechanism that depends on αv integrins. Mice in which αv integrin is depleted in PDGFRβ<sup>+</sup> cells are protected from cardiotoxin and laceration-induced skeletal muscle fibrosis and angiotensin II-induced cardiac fibrosis. In addition, a small-molecule inhibitor of αv integrins attenuates fibrosis, even when pre-established, in both skeletal and cardiac muscle, and improves skeletal muscle function. αv integrin blockade also reduces TGFβ activation in primary human skeletal muscle and cardiac PDGFRβ<sup>+</sup> cells, suggesting that αv integrin inhibitors may be effective for the treatment and prevention of a broad range of muscle fibroses.
GPR101 Mutations are not a Frequent Cause of Congenital Isolated Growth Hormone Deficiency (2016)

Patients with Xq26.3 microduplication present with X-linked acrogigantism (X-LAG) syndrome, an early-childhood form of gigantism due to marked growth hormone (GH) hypersecretion from mixed GH-PRL adenomas and hyperplasia. The microduplication includes GPR101, which is upregulated in patients' tumor tissue. The GPR101 gene codes for an orphan G protein coupled receptor that is normally highly expressed in the hypothalamus. Our aim was to determine whether GPR101 loss of function mutations or deletions could be involved in patients with congenital isolated GH deficiency (GHD). Taking advantage of the cohort of patients from the GENHYPOPIT network, we studied 41 patients with unexplained isolated GHD. All patients had Sanger sequencing of the GPR101 gene and array comparative genome hybridization (aCGH) to look for deletions. Functional studies (cell culture with GH secretion measurements, cAMP response) were performed. One novel GPR101 variant, c.589 G>T (p.V197L), was seen in the heterozygous state in a patient with isolated GHD. In silico analysis suggested that this variant could be deleterious. Functional studies did not show any significant difference in comparison with wild type for GH secretion and cAMP response. No truncating, frameshift, or small insertion-deletion (indel) GPR101 mutations were seen in the 41 patients. No deletion or other copy number variation at chromosome Xq26.3 was found on aCGH. We found a novel GPR101 variant of unknown significance, in a patient with isolated GH deficiency. Our study did not identify GPR101 abnormalities as a frequent cause of GH deficiency.
17O NMR Spectroscopy: Hydrogen-Bonding Effects (2020)

O nuclear magnetic resonance (NMR) spectroscopy is an important method for assessment of numerous structural problems in organic chemistry. This chapter reviews the effect of intramolecular and intermolecular hydrogen bonding on O NMR chemical shifts including hydrogen-bonding solvent interactions from a historical viewpoint. It describes intramolecular hydrogen-bonding studies involving NH and OH proton donors on the O NMR data for carbonyl groups that are currently ongoing in our laboratories. An extensive O NMR study of acetophenones and benzylaldehydes by Fiat and coworkers in 1981 showed the importance of intramolecular hydrogen-bonding effects. Substituent and steric effects were thought to be one order of magnitude smaller than the observed intramolecular hydrogen-bonding effects based on the O NMR data of the analogous o-methoxy substituted compounds. Solvent effect studies by O NMR spectroscopy hold considerable promise for study of solute-solvent interactions, including detection of intramolecular hydrogen bonding by the lack of appreciable solvent effects.
AgMoVO6: A Promising Catalyst for Selective Gas‐Phase Oxidation of o‐Xylene (2010)

MoVing on up: AgMoVO6, a new crystalline catalyst for the gas-phase oxidation of o-xylene, with a remarkably high selectivity to value products, has been developed by high-throughput experimentation. Doping of the catalyst with elements such as P results in further enhancement of the catalytic properties.
Fluorescent In Situ Hybridization Protocols in Drosophila Embryos and Tissues (2008)

Fluorescent in situ hybridization is the standard method for visualizing the spatial distribution of RNA. Although traditional histochemical RNA detection methods suffered from limitations in resolution or sensitivity, the recent development of peroxidase-mediated tyramide signal amplification provides strikingly enhanced sensitivity and subcellular resolution. In this chapter, we describe optimized fluorescent in situ hybridization protocols for Drosophila embryos and tissues utilizing tyramide signal amplification, either for single genes or in a high-throughput format, which greatly increases the sensitivity, consistency, economy, and throughput of the procedure. We also describe variations of the method for RNA-RNA and RNA-protein codetection.
Organocuprates as initiators for the polymerization of methyl methacrylate in THF (1993)

Abstract Several types of lithium organocuprates (I) e.g. R 2 CuLi, RR'CuLi, R 3 CuLi 2 , R 2 CuLi 2 X (X‐ CN, SCN), were prepared and used as polymerization initiators for methyl methacrylate in THF at temperatures ranging from −30 to +20 * C. Polymerization initiated by a mixed homocuprate, e.g. lithium n‐butyl (thien‐2‐yl)cuprate was studied in more detail. Kinetic measurements indicated an overall large (−4 to −14 kcal) apparent negative activation energy of polymerization in the −30 + +20 * C temperature range. The reaction was shown to have a kinetic order of about 1.5 with respect to initiator concentration. Conductance measurements indicate that the equivalent conductance increases with initiator concentration in the 10 −2 + 10 −1 M range indicating the formation of multiple ions formed by intermolecular association. The data are consistent with a polymerization involving aggregated ion pairs of as yet undetermined composition. The negative activation energy is tentatively interpreted as due to the exothermic formation of aggregates existing as highly solvated ion pairs.