gebhart/patrepeval huggingface dataset:
Synchronous Current Compensator for a Self-Balanced Three-Level Neutral Point Clamped Inverter (2014)

This paper presents a synchronous current control method for a three-level neutral point clamped inverter. Synchronous reference frame control based on two decoupled proportional-integral (PI) controllers is used to control the current in direct and quadrature axes. A phase disposition pulse width modulation (PDPWM) method in regular symmetrical sampling is used for generating the inverter switching signals. To eliminate the harmonic content with no phase errors, two first-order low pass filters (LPFs) are used for the <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>d</mml:mi><mml:mi>q</mml:mi></mml:math> currents. The simulation of closed-loop control is done in Matlab/Simulink. The Vertex-5 field programmable gate array (FPGA) in Labview/CompactRio is used for the implementation of the control algorithm. The control and switch pulse generation are done in independent parallel loops. The synchronization of both loops is achieved by controlling the length of waiting time for each loop. The simulation results are validated with experiments. The results show that the control action is reliable and efficient for the load current control.
Small Angle Neutron Scattering Shows Nanoscale PMMA Distribution in Transparent Wood Biocomposites (2021)

Transparent wood biocomposites based on PMMA combine high optical transmittance with excellent mechanical properties. One hypothesis is that despite poor miscibility the polymer is distributed at the nanoscale inside the cell wall. Small-angle neutron scattering (SANS) experiments are performed to test this hypothesis, using biocomposites based on deuterated PMMA and "contrast-matched" PMMA. The wood cell wall nanostructure soaked in heavy water is quantified in terms of the correlation distance <i>d</i> between the center of elementary cellulose fibrils. For wood/deuterated PMMA, this distance <i>d</i> is very similar as for wood/heavy water (correlation peaks at <i>q</i> ≈ 0.1 Å<sup>-1</sup>). The peak disappears when contrast-matched PMMA is used, indeed proving nanoscale polymer distribution in the cell wall. The specific processing method used for transparent wood explains the nanocomposite nature of the wood cell wall and can serve as a nanotechnology for cell wall impregnation of polymers in large wood biocomposite structures.
Synthesis and Anticancer Activity of Fluorinated Analogues of Combretastatin A‐4. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Polarization Aberrations In The SAMEX Solar Vector Magnetograph (1988)

An optical design and polarization analysis of the Air Force/NASA SAMEX solar vector magnetograph optical system is performed. Polarization aberration theory demonstrates that conventional telescope coating designs introduce unacceptably high levels of polarization aberrations into the optical sytem. Several ultra-low polarization mirror and lens coatings designs for this instrument are discussed. Balancing of polarization aberrations at different surfaces is demonstrated.
Early signalling events in the Avr9/Cf‐9‐dependent plant defence response (2000)

Abstract Resistance of tomato to the leaf mould fungus Cladosporium fulvum is controlled by the interaction between a plant-encoded resistance gene (Cf-9) and pathogen-encoded avirulence (Avr9) gene. Our objective is to understand the underlying molecular mechanisms that transmit the Cf-9/Avr9-dependent pathogen perception event and activate the plant defence response. Our approach toward the understanding of Cf-function is based on the analysis of early Cf-9/Avr9-mediated responses and signalling events. Because Cf-9 transgenically expressed in tobacco retains its specificity and activity to the Avr9 elicitor, signalling experiments were conducted in the heterologous system using these transgenic lines or derived Cf9 tobacco cell cultures. Among the earliest responses to the Avr9/Cf-9 elicitation event were rapid changes in ion-fluxes, the synthesis of active oxygen species (AOS), probably catalysed by a plant NADPH-oxidase, and the transient activation of two MAP kinases. These kinases were identified as WIPK (wounding-induced protein kinase) and SIPK (salicylic-acid induced kinase) from tobacco. Studies with pharmacological inhibitors suggested that the MAP kinases are located in an independent signalling pathway from the Avr9/Cf-9-dependent synthesis of AOS. SIPK and WIPK were involved in pathogen-related elicitation processes as well as in abiotic stress responses. This indicates that the plant defence is triggered via a signalling network that shares components with pathways originating from abiotic environmental stress stimuli.
SGM3D: Stereo Guided Monocular 3D Object Detection (2022)

Monocular 3D object detection aims to predict the object location, dimension and orientation in 3D space alongside the object category given only a monocular image. It poses a great challenge due to its ill-posed property, which is a critical lack of depth information in the 2D image plane. While existing approaches leverage off-the-shelf depth estimation or rely on LiDAR sensors to mitigate this problem, dependence on the additional depth model or expensive equipment severely limits their scalability to generic 3D perception. In this paper, we propose a stereo-guided monocular 3D object detection framework, dubbed SGM3D, which aligns the monocular feature to the stereo feature and exploits the network's ability of generating the cross-modal feature for accurate 3D object detection. We present a multi-granularity feature alignment (MG-FA) mechanism to exploit the network's ability to generate stereo-mimicking features given only monocular cues. Coarse feature-level, as well as fine anchor-level feature alignment, are both leveraged for monocular feature guidance. In addition, we introduce an IoU matching-based feature alignment (IoU-MA) method for object-level feature alignment between the stereo and monocular predictions to alleviate the mismatches while adopting the MG-FA. Extensive experiments on the KITTI datasets demonstrate the effectiveness of our method. Code is publicly available at <uri xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">https://github.com/zhouzheyuan/sgm3d</uri> .
High nigral iron deposition in LRRK2 and Parkin mutation carriers using R2* relaxometry (2015)

These results are consistent with increased iron load in LRRK2- and Parkin-mutation carriers. The increased R2* in asymptomatic PD-mutation carriers suggests that iron deposition occurs early during the preclinical phase of the disease. R2* measurements may be used as markers for investigating nigrostriatal damage in preclinical mutation-carrying patients.
Training the Workforce for 21st-Century Science (2016)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA HomeNew OnlineCurrent IssueFor Authors Podcasts Clinical Reviews Editors' Summary Medical News Author Interviews More Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA journal
Combining ability and performance of three-way maize hybrids for grain yield and resistance to maize lethal necrosis under contrasting environments (2022)

Abstract Combining ability studies have been extensively used to assess gene action responsible for various traits including disease resistance in maize. Some backcross (BC 3 F 2 ) and dihaploid (DH) lines developed through marker assisted selection have not been tested for their yield performances in hybrid combinations. A total of 16 BC 3 F 2 lines and their parental checks and 60 DH lines including lines and their parental checks were crossed to two single cross testers (CML312/CML442 and CML395/CML444) using Line x Tester design. The 152 three-way hybrids generated were evaluated for yield performance and other agronomic traits under artificial MLN inoculation, low nitrogen soil and optimum conditions in Kenya and South Sudan in 2019. Significant genotype, GxE, general combining ability (GCA) and specific combining ability (SCA) effects ( p ≤0.01) were detected for grain yield (t/ha) and maize lethal necrosis (MLN) scores. GCA effects were preponderant over SCA effects for most traits. High broad sense and moderate narrow sense heritability estimates for all traits across management options were detected. This implied that these traits could be improved through recurrent selection. DH lines D3, D14, D57 and BC 3 F 2 lines BCL3, BCL5, BCL8 showed desirable GCA effects for MLN resistance and grain yield. DH derived hybrids DH70, DH43, DH18 and DH40; and backcross (BC) derived hybrids BH28 and BH01 demonstrated desirable SCA effects for the same traits. Deployment of these MLN resistant lines into breeding programmes should result into improved MLN resistance and increased grain yields. The superior hybrids will provide desirable options for farmers who continue to experience low average maize yields due to MLN infections.
Plotting XPS Narrow Scans (and Other data) with MATLAB, 1. Using the 'plot' and 'subplot' functions. (2020)

As researchers, we often focus more on data collection than data work-up. However, skillfully plotting data so that it can be effectively visualized is often an important step toward making it impactful. Data visualization in academic writing takes the form of plots, figures, graphs, spectra, etc., which are often combined with cartoons and schematics. An important goal of data visualization is to make complex data and concepts more accessible, understandable, and usable, and to do this in a concise manner – ‘a picture is worth a thousand words’ as the old cliché goes. Data visualization is both art and science, where, of course, data visualization depends on the type of data in question. Herein, we discuss ways of representing/plotting data using MATLAB from the MathWorks<sup>®</sup>.
1,4-Oxazine β-Secretase 1 (BACE1) Inhibitors: From Hit Generation to Orally Bioavailable Brain Penetrant Leads (2015)

1,4-Oxazines are presented, which show good in vitro inhibition in enzymatic and cellular BACE1 assays. We describe lead optimization focused on reducing the amidine pKa while optimizing interactions in the BACE1 active site. Our strategy permitted modulation of properties such as permeation and especially P-glycoprotein efflux. This led to compounds which were orally bioavailable, centrally active, and which demonstrated robust lowering of brain and CSF Aβ levels, respectively, in mouse and dog models. The amyloid lowering potential of these molecules makes them valuable leads in the search for new BACE1 inhibitors for the treatment of Alzheimer's disease.
Computing Tate Pairing on Smartcards (2005)

In this paper, we present the results of computing the Tate pairing using a supersingular elliptic curve defined over a prime field. The aim of this work is to demonstrate the feasibility of the primitives of identity based cryptosystem for application in embedded processors such as a smartcard. The most computationally intensive operation in an Identity Based Protocol is the calculation of a pairing function. We report the timing of Tate pairing computation for a PC platform and for the 32-bit ST22 smartcard microprocessor. The use of supersingular elliptic curves permits the use of a field where the characteristic is a large prime p with low Hamming weight. This results in a faster modular reduction operation when compared to the use of Montgomery modular multiplication used in literature where MNT curves are adopted.
Micelle-enabled clean and selective sulfonylation of polyfluoroarenes in water under mild conditions (2018)

Proline-based designer surfactant FI-750-M has been demonstrated to enable selective nucleophilic aromatic substitution of polyfluoro(hetero)arenes by sulfinate salts in water under mild micellar conditions.
Stimulus Coding Rules for Perceptual Learning (2008)

Perceptual learning of visual features occurs when multiple stimuli are presented in a fixed sequence (temporal patterning), but not when they are presented in random order (roving). This points to the need for proper stimulus coding in order for learning of multiple stimuli to occur. We examined the stimulus coding rules for learning with multiple stimuli. Our results demonstrate that: (1) stimulus rhythm is necessary for temporal patterning to take effect during practice; (2) learning consolidation is subject to disruption by roving up to 4 h after each practice session; (3) importantly, after completion of temporal-patterned learning, performance is undisrupted by extended roving training; (4) roving is ineffective if each stimulus is presented for five or more consecutive trials; and (5) roving is also ineffective if each stimulus has a distinct identity. We propose that for multi-stimulus learning to occur, the brain needs to conceptually "tag" each stimulus, in order to switch attention to the appropriate perceptual template. Stimulus temporal patterning assists in tagging stimuli and switching attention through its rhythmic stimulus sequence.
ChemInform Abstract: Aromatische Amino‐Claisen‐Umlagerungen. (1977)

Abstract Die a) thermische und b) säurekatalysierte Umlagerung der Aniline (I), (II) und (III) (sowie einiger deuterierter Analoger deren Darstellung zunächst beschrieben wird, wird ausführlich untersucht.
SEC24 isoform specificity regulates the assembly of γ‐secretase from dimeric subcomplexes (2020)

Abstract Background γ‐Secretase is a diaspartyl protease with presenilin (PSEN) as the catalytic subunit. It targets a plethora of type I transmembrane proteins and, as such, affects a broad range of physiological processes. Because of this, aberrant functioning of γ‐secretase is linked to several diseases including cancer and Alzheimer’s disease (AD). Herein, mutations in the PSEN genes are associated with rare cases of familial AD and shift the production to longer, more aggregation prone amyloid β peptides. γ‐Secretase consists, besides the catalytic component PSEN, of nicastrin, APH1 and PEN‐2 that are co‐translationally translocated in the endoplasmic reticulum (ER). As γ‐secretase has a stoichiometry of 1:1:1:1, the assembly process is spatially and temporally regulated. Although it is generally agreed that this occurs in early biosynthetic compartments, it remains far from understood whether full assembly occurs already in the ER and to what extent Golgi‐to‐ER recycling is involved. Method We used advanced cell fractionation protocols and an in vitro reconstituted ER budding assay to explore in detail the stepwise assembly process of γ‐secretase in early biosynthetic compartments. Result Cell fractionation combined with blue native electrophoresis shows that subcomplexes are mainly present in ER‐enriched fractions while full complexes appear in the ER‐Golgi intermediate compartment, indicating that final assembly occurs beyond the ER. In vitro reconstitution of ER export reveals that none of the γ‐secretase subunits is required for ER‐exit of the others. However, knock‐out of any subunit induces the accumulation of preceding subcomplexes in de novo formed COPII vesicles. Mutating a motif in the cytosolic loop domain of PSEN1, which is lost in the familial AD‐associated PSEN1∆E9 mutant, abrogates ER‐exit of PSEN1 as well as PEN‐2, but not of nicastrin. This is explained molecularly by the selectivity of Sec24A/B and Sec24C/D in packaging PSEN1 and nicastrin, respectively, and further argues against full complex assembly prior to ER‐exit. Conclusion In conclusion, our data support a model wherein individual subunits and dimeric subcomplexes preferentially exit the ER. Full assembly likely occurs in intermediate compartment/ cis ‐Golgi allowing complexes to escape active Golgi‐to‐ER recycling as part of a secondary quality control mechanism in controlling cellular γ‐secretase levels and activity.
On-Line Thermal Barrier Coating Monitoring for Real-Time Failure Protection and Life Maximization (2005)

Under the sponsorship of the U. S. Department of Energy's National Energy Laboratory, Siemens Westinghouse Power Corporation proposes a four year program titled, ''On-Line Thermal Barrier Coating (TBC) Monitor for Real-Time Failure Protection and Life Maximization'', to develop, build and install the first generation of an on-line TBC monitoring system for use on land-based advanced gas turbines (AGT). Federal deregulation in electric power generation has accelerated power plant owner's demand for improved reliability availability maintainability (RAM) of the land-based advanced gas turbines. As a result, firing temperatures have been increased substantially in the advanced turbine engines, and the TBCs have been developed for maximum protection and life of all critical engine components operating at these higher temperatures. Losing TBC protection can therefore accelerate the degradation of substrate components materials and eventually lead to a premature failure of critical component and costly unscheduled power outages. This program seeks to substantially improve the operating life of high cost gas turbine components using TBC; thereby, lowering the cost of maintenance leading to lower cost of electricity. Siemens Westinghouse Power Corporation has teamed with Indigo Systems, a supplier of state-of-the-art infrared camera systems, and Wayne State University, a leading research organization in the field of infrared non-destructive examination (NDE), to complete the program.
ChemInform Abstract: Synthesis of, and Lack of Inhibition of a Rhamnosidase by, Both Enantiomers of Deoxyrhamnojirimycin and Rhamnonolactam: β‐ Mannosidase Inhibition by δ‐Lactams. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract: Practical Synthesis of 2,6‐Dideoxy‐D‐lyxo‐hexose (′′2‐Deoxy‐D‐fucose′′) from D‐Galactose. (1999)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
RF FET layout and modeling for design success in RFCMOS technologies (2005)

This paper presents challenges in creating high quality RF FET layouts and models in CMOS technologies spanning 0.25 /spl mu/m to 90 nm nodes. The focus is on developing a comprehensive methodology to provide robust, high performance parameterized RF FET layout cells and corresponding scalable RF models to enable RF designs that fully leverage the cost benefit potential of CMOS technology.
A first‐in‐human study to evaluate the safety, tolerability and pharmacokinetics of RP3128, an oral calcium release‐activated calcium (CRAC) channel modulator in healthy volunteers (2020)

The safety, tolerability and PK/PD profile of RP3128 demonstrates its potential to be developed in inflammatory disorders and support further clinical development (ClinicalTrials.gov number: NCT02958982).
Grape Pomace Extracts as Green Corrosion Inhibitors for Carbon Steel in Hydrochloric Acid Solutions (2012)

The inhibitive action of grape pomace extracts against the corrosion of C-steel in a 1 mol L-1 HCl solution was investigated using electrochemical impedance spectroscopy, potentiodynamic polarization curves, weight loss measurements and surface analysis. Hydroalcoholic extracts of grape pomace were analyzed in different concentrations and were found to act as effective corrosion inhibitors for the tested system. The inhibition efficiency increased with increasing extract concentration and decreased with temperature. The adsorption of components of the grape pomace extracts on the surface of the C-steel followed the Langmuir adsorption isotherm.
Long-Haul 40 Gb/s RZ-DPSK Transmission over 4,450 km with 150-km Repeater Spacing using Raman Assisted EDFAs (2007)

40Gb/s RZ-DPSK signals were successfully transmitted over 4450km with 150km repeater spacing (33dB span loss) using Raman assisted EDFAs. The performance was compared with EDFA only amplification and 110km repeater spacing. Long-term Q-factor fluctuations were also quantified for Raman-assisted amplification.
Porosity tuning of the optical properties of mesoporous silica planar defect in macroporous silica opal (2012)

Periodic mesoporous silica films were embedded between photonic crystals to form defect-based monolithic structures capable of post-growth tuning. Tetramethyl orthosilicate was infiltrated into monolithic structures in order to form silica layers in their void spaces, resulting in changes to the optical spectra. With the increase in the number of infiltration cycles, the optical signatures of the defect-based monolithic structures red-shift, caused mainly by the increase in the effective index of refraction of the entire structure. Furthermore, the red-shift of the optical signatures in monolithic structures deviates when compared to the net-effect of infiltration on stand-alone structures of periodic mesoporous silica films and photonic crystals. Simulations based on scalar wave approximation corroborate the results obtained by ellipsometry, UV-VIS spectroscopy, scanning electron microscopy, and x-ray diffraction experiments.
New Anthraquinones from a Marine Streptomyces sp. – Isolation, Structure Determination and Biological Activities (2006)

Two new anthraquinones were isolated from the marine Streptomyces sp. B8000, in addition to the known metabolites 3,8-dihydroxy-1-propylanthraquinone-2-carboxylic acid (1a), indole-3- carboxylic acid, 2-desoxythymidin, indole-3-acetic acid methyl ester, N-acetyltyramine, and nicotinic acid. The structures of the new compounds were established as 8-hydroxy-3-methoxy-1- propylanthraquinone (2a) and 3,8-dihydroxy-1-propylanthraquinone (2c) on the basis of extensive spectroscopic analyses. Some derivatives were prepared and their biological activities were studied.
Souvenirs du monde des montagnes (2009)

This paper describes a particular book called Souvenirs du monde des montagnes, which draws its iconography from the history of a Swiss mountain family from 1910 to 1930. By simply dipping into the first few pages, the reader will be lost between real and virtual universes, wonder about the evolution of the images' meanings, and question an object's true content. This setup, developed using state-of-the-art computer vision technology, offers unprecedented freedom: we can make technological references disappear to place the user in fruitful turmoil between visible and hidden meanings. The shadow of a bird flies over the pages, foxes' lanterns light up the text, paper mountains emerge. once the last page has been turned, the reader will never look at books in the same way again.