gebhart/patrepeval huggingface dataset:
Fabrication and Characterization of Large-Area 3-D Photonic Crystals (2006)

Full bandgap (3D) photonic crystal materials offer a means to precisely engineer the electromagnetic reflection, transmission, and emission properties of surfaces over wide angular and spectral ranges. However, very few 3D photonic crystals have been successfully demonstrated with areas larger than 1 cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> . Large sheets of photonic bandgap (PBG) structures would be useful, for example, as hot or cold mirrors for passively controlling the temperature of satellites. For example, an omni-directional 3D PBG structure emitting only at wavelengths shorter than 8 microns radiates only 7% of what a black body would at 200degK while radiating more than 40% at 400degK. 3D PBG materials may also find application in thermophotovoltaic energy generation and scavenging, as well as in wide field of view spectral filtering. Sandia National Laboratory is investigating a variety of methods for the design, fabrication, and characterization of PBG materials, and three methods are being pursued to fabricate large areas of PBG material. These methods typically fabricate a mold and then fill it with metal to provide a high refractive index contrast, enabling a full 3D bandgap to be formed. The most mature scheme uses silicon MEMS lithographic fabrication means to create a mold which if filled by a novel tungsten deposition method. A second method uses LIGA to create a mold in PMMA, which is filled by electro-deposition of gold, copper, or other materials. A third approach uses nano-imprinting to define the mold, which is filled using evaporative deposition or atomic layer deposition of metals or other materials. Details of the design and fabrication processes and experimental measurements of the structures are presented at the conference
Memento Player: Shared Multi-Perspective Playback of Volumetrically-Captured Moments in Augmented Reality (2023)

Capturing and reliving memories allow us to record, understand and share our past experiences. Currently, the most common approach to revisiting past moments is viewing photos and videos. These 2D media capture past events that reflect a recorder’s first-person perspective. The development of technology for accurately capturing 3D content presents an opportunity for new types of memory reliving, allowing greater immersion without perspective limitations. In this work, we adopt 2D and 3D moment-recording techniques and build a moment-reliving experience in AR that combines both display methods. Specifically, we use AR glasses to record 2D point-of-view (POV) videos, and volumetric capture to reconstruct 3D moments in AR. We allow seamless switching between AR and POV videos to enable immersive moment reliving and viewing of high-resolution details. Users can also navigate to a specific point in time using playback controls. Control is synchronized between multiple users for shared viewing.
High-Speed Ring Oscillator based Sensors for Remote Side-Channel Attacks on FPGAs (2019)

FPGAs have been widely adopted in cloud datacenters and System-on-Chip for hardware acceleration purposes during the past few years. For flexibility and efficiency reasons, cloud FPGA fabrics are likely to be shared between multiple users. Despite the logical isolation suggested to protect each tenant, multi-user FPGA environment raises crucial questions about the potential security threats that it may represent. Recently, a series of papers demonstrated that a malicious user could be able to use its rented logic to perform remote side-channel and fault attacks on other user assets located inside the fabric or in the surrounding chips. In this paper, we present a novel implementation method for ring oscillator based voltage sensors that enables runtime supply voltage fluctuation measurement. Considering a multi-user FPGA cloud scenario, we evaluate our sensor performances for side-channel purposes by performing CPA attacks against a hardware AES module instantiated within the same FPGA fabric. Then, we compare our results with existing voltage sensors and also demonstrate that, when calibrated, our sensors can provide results similar to traditional electromagnetic side-channel setups.
Advanced Delay-locked Loop Architecture for Chip-to-Chip Communication (2002)

A challenging component in high-speed data links is the clock and data recovery circuit (CDR). Two primary functions of a CDR are to extract the clock corresponding to the input data and then to resample the input data. The conventional technique uses a phase-locked loop (PLL) to tune the frequency and phase of a voltage-controlled oscillator (VCO) to match that of the input data. In some applications, such as chip-to-chip communication, a reference clock that is perfectly matched in frequency to the signal sequence is available. However, the clock and data signals are often mismatched in phase due to different propagation delays on the PC board. In such cases, using a delay-locked loop (DLL), as shown in Figure 1, instead of a PLL allows for much simpler design, since only a phase adjustment is necessary [1].
Article Commentary: Regenerative Rehabilitation: An Innovative and Multifactorial Approach to Recovery from Stroke and Brain Injury (2017)

There is currently a dearth of treatment options for stroke or traumatic brain injury that can restore cognitive and motor function. Regenerative and translational medicine have ushered forth promising new methods for mediating recovery in the central nervous system, the most salient of which are rehabilitation and stem cell therapies that, when combined, result in more pronounced recovery than one approach alone.
Introduction au logiciel Minitab sous Windows (2006)

Principes de base pour utiliser le logiciel Minitab.
Type III apical transportation of root canal (2012)

Procedural accidents leading to complications such as canal transportation have been ascribed to inapt cleaning and shaping concepts. Canal transportation is an undesirable deviation from the natural canal path. Herewith a case of apical transportation of root canal resulting in endodontic retreatment failure and its management is presented. A healthy 21-year-old young male presented discomfort and swelling associated with painful endodontically retreated maxillary incisor. Radiograph revealed periradicular radiolucency involving underfilled 11 and overfilled 12. Insufficiently obturated 11 exhibited apical transportation of canal. This type III transportation was treated by periradicular surgery and repair using white mineral trioxide aggregate (MTA). Comfortable asymptomatic patient presented uneventful healing at third and fourth month recall visits. A decrease in the size of radiolucency in radiograph supported the clinical finding. In the present case, MTA is useful in repairing the transportation defect. The result of these procedures is predictable and successful.
Multi-watt electpjc power from a microfabricated permanent-magnet generator (2005)

This paper presents the design, fabrication, and characterization of permanent magnet (PM) generators for use in microscale power generation systems. The generators are three phase, axial flux, synchronous machines, each consisting of a multipole surface wound stator and PM rotor. The microfabricated windings, with small interconductor gaps and variable width geometry, are the key enabler for high power density. At a rotational speed of 120,000 rpm, one such generator demonstrates 2.6 W of mechanical-to-electrical power conversion and, coupled to a transformer and rectifier, delivers 1.1 W of DC electrical power to a resistive load. This Watt-scale electrical power generation demonstrates the viability of scaled PM machines for practical applications.
Quantitative evaluation of information loss for Compton cameras (1999)

Compton cameras decouple the inverse relationship between spatial resolution and detection sensitivity which compromises the performance of conventional collimated cameras. However, this improvement is usually achieved at the expense of the amount of information conveyed by each detected photon. In this paper, we propose a simple approach to calculate the information loss for a ring Compton camera. We describe this information loss as "decoding penalty", defined as the ratio of the variance of reconstructed intensity for a pixel of interest for a ring Compton camera to that for a mechanically collimated camera normalized on a per-detected-photon basis. The uniform Crame/spl acute/r-Rao bound, our mathematical tool, provides a lower bound on the variance that is dependent on the system and data statistics alone, rather than the estimator. The results suggest that ring Compton cameras perform comparably to conventional collimated cameras at an incident photon energy of 140 keV and substantially outperform their counterparts at 364 keV.
On compressible pairings and their computation (2007)

Abstract. In this paper we provide explicit formulæ to compute bilinear pairings in compressed form, and indicate families of curves where particularly generalised versions of the Eta and Ate pairings due to Zhao et al. are especially efficient. With the new formulæ it is possible to entirely avoid Fpk arithmetic during pairing computation on elliptic curves over Fp with even embedding degree k. Using our new method all intermediate results in the Miller loop are represented by just one Fpk/2 element and manipulated in compressed form. For certain families of ordinary curves with embedding degree k = 6m all arithmetic can be done in a subfield of size p m and the representation can be further compressed to two Fpm elements.
Inhibition of interleukin-6 on matrix protein production by glomerular mesangial cells and the pathway involved (2020)

Activation of immunological pathways and disturbances of extracellular matrix (ECM) dynamics are important contributors to the pathogenesis of chronic kidney diseases. Glomerular mesangial cells (MCs) are critical for homeostasis of glomerular ECM dynamics. Interleukin-6 (IL-6) can act as a pro/anti-inflammatory agent relative to cell types and conditions. This study investigated whether IL-6 influences ECM protein production by MCs and the regulatory pathways involved. Experiments were carried out in cultured human MCs (HMCs) and in mice. We found that overexpression of IL-6 and its receptor decreased the abundance of fibronectin and collagen type IV in MCs. ELISA and immunoblot analysis demonstrated that thapsigargin [an activator of store-operated Ca<sup>2+</sup> entry (SOCE)], but not the endoplasmic reticulum stress inducer tunicamycin, significantly increased IL-6 content. This thapsigargin effect was abolished by GSK-7975A, a selective inhibitor of SOCE, and by silencing Orai1 (the channel protein mediating SOCE). Furthermore, inhibition of NF-κB pharmacologically and genetically significantly reduced SOCE-induced IL-6 production. Thapsigargin also stimulated nuclear translocation of the p65 subunit of NF-κB. Moreover, MCs overexpressing IL-6 and its receptor in HMCs increased the content of the glucagon-like peptide-1 receptor (GLP-1R), and IL-6 inhibition of fibronectin was attenuated by the GLP-1R antagonist exendin 9-39. In agreement with the HMC data, specific knockdown of Orai1 in MCs using the targeted nanoparticle delivery system in mice significantly reduced glomerular GLP-1R levels. Taken together, our results suggest a novel SOCE/NF-κB/IL-6/GLP-1R signaling pathway that inhibits ECM protein production by MCs.
Copper‐Catalyzed Arylation of β‐Amino Alcohols. (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
Abstract 297: Innovation in delivering synthetically challenging bicyclic arginase inhibitors to enhance immunotherapy (2021)

Abstract Arginase overexpression has been associated with poor survival rates in advanced cancer patients treated with Keytruda. High levels of Arginase may lead to a depletion of arginine within the tumor microenvironment, inhibiting the immune response. Thus, arginase inhibition has the potential to greatly enhance immunotherapy treatment. Discovering novel arginase inhibitors was met with several challenges including analyzing/purifying extremely polar chemical matter without chromophores, synthetically challenging space, and poor bioavailability of compounds with ClogP less than minus two. Cross-functional collaborations and innovations rapidly overcame these challenges. Structural chemistry and modeling guided the design of novel arginase inhibitors. Analytical and purification groups developed innovative analytical/purification methods. Novel technologies including ReatIR and Vapourtec flow system, provided key intermediates to enable chartering into synthetically challenging space. Through creative cyclization strategies and active transport strategy to improve bioavailability, the team ultimately delivered a diverse set of potent and extremely synthetically challenging arginase inhibitors to study the potential of arginase inhibition. Preliminary in vivo evaluation showed single agent efficacy in an EMT6 model. These arginase inhibitors have the potential to enhance immunotherapy. Citation Format: Derun Li, Hongjun Zhang, Thomas W. Lyons, Theodore A. Martinot, Abdelghani Achab, Min lu, Lisa M. Nogle, Spencer McMinn, Matthew J. Mitcheltree, Matthew Childers, Qinglin Pu, Symon Gathiaka, Anand Palani, Kalyan Chakravarthy, Amy D. DeCastro, Jennifer O'Neil, Roshi Afshar, Nicole C. Walsh, Peter W. Fan, Mangeng Cheng, Richard Miller, Amy Doty, Rachel Palte, Hai-Young Kim, Josep Saurí, Adam Beard, Christopher Brynczka, Christian Fischer. Innovation in delivering synthetically challenging bicyclic arginase inhibitors to enhance immunotherapy [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2021; 2021 Apr 10-15 and May 17-21. Philadelphia (PA): AACR; Cancer Res 2021;81(13_Suppl):Abstract nr 297.
Effects of lamellar thickness on misfit dislocation introduction and mechanical properties of γ/α2nano-lamellar TiAl alloys (2010)

Stress-strain behavior of lamellar Ti-38Al-3Zr and -3Nb alloys with average lamellar thickness ranging from 10 to 1000 nm were studied at room temperature. Their yield stresses decrease from a high value of coherent lamellar structures to a low value after introducing misfit dislocations onto lamellar boundaries. Their strain hardening rates increase with decreasing lamellar thickness, and then drop to a low level when the misfit dislocations become absent. There is critical thickness of γ lamellae for introduction of misfit dislocations. The thickness decreases with increasing lattice misfit between the constituent phases.
InP membrane-based microlasers on silicon wafer: microdisks vs photonic crystal cavities (2002)

Microdisk and photonic crystal (PC) cavity lasers were fabricated on InP based heterostructures integrated on silicon wafers. Single InGaAs quantum well, multiple InGaAs quantum wells and InAs quantum wires are used as active layers. Laser emission is achieved on quantum well based microdisk and PC microcavities. A comparison is made between different combinations of microcavity shapes and active material.
Mapping of Epitopes Recognized by Antibodies Induced by Immunization of Mice with PspA and PspC (2014)

Pneumococcal surface protein A (PspA) and pneumococcal surface protein C (PspC) are important candidates for an alternative vaccine against pneumococcal infections. Since these antigens show variability, the use of variants that do not afford broad protection may lead to the selection of vaccine escape bacteria. Epitopes capable of inducing antibodies with broad cross-reactivities should thus be the preferred antigens. In this work, experiments using peptide arrays show that most linear epitopes recognized by antibodies induced in mice against different PspAs were located at the initial 44 amino acids of the mature protein and that antibodies against these linear epitopes did not confer protection against a lethal challenge. Conversely, linear epitopes recognized by antibodies to PspC included the consensus sequences involved in the interaction with human factor H and secretory immunoglobulin A (sIgA). Since linear epitopes of PspA were not protective, larger overlapping fragments containing 100 amino acids of PspA of strain Rx1 were constructed (fragments 1 to 7, numbered from the N terminus) to permit the mapping of antibodies with conformational epitopes not represented in the peptide arrays. Antibodies from mice immunized with fragments 1, 2, 4, and 5 were capable of binding onto the surface of pneumococci and mediating protection against a lethal challenge. The fact that immunization of mice with 100-amino-acid fragments located at the more conserved N-terminal region of PspA (fragments 1 and 2) induced protection against a pneumococcal challenge indicates that the induction of antibodies against conformational epitopes present at this region may be important in strategies for inducing broad protection against pneumococci.
Performance of a Radio Resource Allocation Algorithm for UTRAN LTE Uplink (2007)

UTRAN LTE uplink is a SC-FDMA based system currently under development within 3GPP. The decision of basing the system on the packet switched technology attracts a lot of attention about the possible designs of resource allocation strategies. In this work we propose an algorithm which distributes the available bandwidth proportionally to the channel conditions while meeting the SINR target by means of power control. A simple resource allocation scheme which is fair with respect to bandwidth allocation is used as baseline reference. The comparison is carried out in terms of SINR distribution, user throughput and cell throughput. The results show that the proposed algorithm, when combined with slow power control, is able to improve the average cell throughput by approximately 23% with almost no reduction of the 5% outage average user throughput.
Treatment of Diarrhea-Predominant Irritable Bowel Syndrome with Traditional Chinese Herbal Medicine: A Randomized Placebo-Controlled Trial (2006)

The use of this herbal formulation for diarrhea-predominant IBS did not lead to global symptom improvement. Further controlled clinical studies may be necessary to characterize the role of TCM in the management of IBS.
Transient behavior of electrical conductivity in low‐density polyethylene in the presence of acetophenone (2021)

Abstract The transient current in low‐density polyethylene (LDPE) is studied, particularly in the presence of the small organic molecule acetophenone (ACP). Crosslinked LDPE is used extensively in high‐voltage power transmission, and acetophenone is a common byproduct of the crosslinking chemistry. Time‐dependent current measurements of LDPE with and without ACP soaked into the polymer as well as at one or both electrodes are performed by applying step voltages. The results demonstrate that the presence of ACP causes a deviation in the predicted power‐law current decay, suggesting that electron and hole injection at the anode and cathode, respectively, are affected by the presence of this small organic molecule. ACP contributes both to the ionic conduction and charge hopping mechanism. The charge mobility depends on the applied electric field and the sample thickness. The results suggests that the dispersive charge transport phenomenon influences the measured current. This study shows how such a molecule may alter charge transport in polyethylene.
Chimeric human parainfluenza virus bearing the Ebola virus glycoprotein as the sole surface protein is immunogenic and highly protective against Ebola virus challenge (2021)

We generated a new live-attenuated vaccine against Ebola virus (EBOV) based on a chimeric virus HPIV3/ΔF-HN/EboGP that contains the EBOV glycoprotein (GP) as the sole transmembrane envelope protein combined with the internal proteins of human parainfluenza virus type 3 (HPIV3). Electron microscopy analysis of the virus particles showed that they have an envelope and surface spikes resembling those of EBOV and a particle size and shape resembling those of HPIV3. When HPIV3/ΔF-HN/EboGP was inoculated via apical surface of an in vitro model of human ciliated airway epithelium, the virus was released from the apical surface; when applied to basolateral surface, the virus infected basolateral cells but did not spread through the tissue. Following intranasal (IN) inoculation of guinea pigs, scattered infected cells were detected in the lungs by immunohistochemistry, but infectious HPIV3/ΔF-HN/EboGP could not be recovered from the lungs, blood, or other tissues. Despite the attenuation, the virus was highly immunogenic, and a single IN dose completely protected the animals against a highly lethal intraperitoneal challenge of guinea pig-adapted EBOV.
Alice's adventures in an immersive mixed reality environment (2012)

Immersive mixed reality environments offer new possibilities to reproduce reality or embodied presence with constructing elaborate fantasy worlds and provide to the user an intense and seemingly real experience. Mixed reality gives possibilities to create deeply dimensional narratives and simulations that put the user in the center of the action. In this work we describe an interactive mixed reality installation named Alice, consisting of six separate stages based on the narrative “Alice's Adventures in Wonderland”. To be able to achieve the intended experience we have to build complex and heterogeneous distributed system, composed of sensors, actuators, virtual reality, application components and variety of processing components that manage the flow of context information between the sensors/actuators and applications.
Design Rules for Template‐Confined DNA‐Mediated Nanoparticle Assembly (2018)

Template-based strategies are becoming increasingly important for controlling the position of nanoparticle-based (NP-based) structures on surfaces for a wide variety of encoding and device fabrication strategies. Thus, there is an increasing need to understand the behavior of NPs in confined spaces. Herein, a systematic investigation of the diffusion and adsorption properties of DNA-modified NPs is presented in lithographically defined, high-aspect-ratio pores using a template-confined, DNA-mediated assembly. Leveraging the sequence-specific binding affinity of DNA, it is discovered that although NP adsorption in deep polymer pores follows a traditional Langmuir adsorption model when under thermodynamic control, such NPs kinetically follow Fick's classical law of diffusion. Importantly, these observations allow one to establish design rules for template-confined, DNA-mediated NP assembly on substrates based on pore dimensions, NP size and shape, NP concentration, temperature, and time. As a proof-of-concept example, these design rules are used to engineer a vertical, four-layer assembly consisting of individual octahedral NPs stacked on top of one another, with in-plane positioning defined by pores generated by e-beam lithography.
The wordometer 2.0 (2016)

On the basis of the motivation to increase daily reading volumes, this paper introduces an implementation of "Wordometer 2.0," which counts the number of read words in a day. While word count estimation using eye tracking glasses or medical EOG (Electrooculography) sensors has been already proposed, our aim is to implement the idea on an affordable device to quantify readings in the whole day. We utilize commercial EOG glasses designed for everyday use. Our method was evaluated with a dataset involving five readers with 11% error rate with user-independent training.