gebhart/patrepeval huggingface dataset:
Learning Contextualized User Preferences for Co‐Adaptive Guidance in Mixed‐Initiative Topic Model Refinement (2021)

Abstract Mixed‐initiative visual analytics systems support collaborative human‐machine decision‐making processes. However, many multi‐objective optimization tasks, such as topic model refinement, are highly subjective and context‐dependent. Hence, systems need to adapt their optimization suggestions throughout the interactive refinement process to provide efficient guidance. To tackle this challenge, we present a technique for learning context‐dependent user preferences and demonstrate its applicability to topic model refinement. We deploy agents with distinct associated optimization strategies that compete for the user's acceptance of their suggestions. To decide when to provide guidance, each agent maintains an intelligible, rule‐based classifier over context vectorizations that captures the development of quality metrics between distinct analysis states. By observing implicit and explicit user feedback, agents learn in which contexts to provide their specific guidance operation. An agent in topic model refinement might, for example, learn to react to declining model coherence by suggesting to split a topic. Our results confirm that the rules learned by agents capture contextual user preferences. Further, we show that the learned rules are transferable between similar datasets, avoiding common cold‐start problems and enabling a continuous refinement of agents across corpora.
Comparative Evaluation of Handheld Robot-Aided Intraocular Laser Surgery (2016)

This paper presents robot-aided intraocular laser surgery using a handheld robot known as Micron. The micromanipulator enables visual servoing of a laser probe, while maintaining a constant distance of the tool tip from the retinal surface. Automated, semiautomated, and unaided manual performance in patterned laser retinal photocoagulation is compared.
Proteomics, Metabolomics, and Immunomics on Microparticles Derived From Human Atherosclerotic Plaques (2009)

This study provides the first evidence that immunoglobulins are present within MPs derived from plaque macrophages, that the portfolio of plaque antibodies is different from circulating antibodies in plasma, and that anticarbohydrate antibodies are retained in human atherosclerotic lesions.
o'zapft is (2017)

At the heart of many computer network planning, deployment, and operational tasks lie hard algorithmic problems. Accordingly, over the last decades, we have witnessed a continuous pursuit for ever more accurate and faster algorithms. We propose an approach to design network algorithms which is radically different from most existing algorithms. Our approach is motivated by the observation that most existing algorithms to solve a given hard computer networking problem overlook a simple yet very powerful optimization opportunity in practice: many network algorithms are executed repeatedly (e.g., for each virtual network request or in reaction to user mobility), and hence with each execution, generate interesting data: (problem,solution)-pairs. We make the case for leveraging the potentially big data of an algorithm's past executions to improve and speed up future, similar solutions, by reducing the algorithm's search space. We study the applicability of machine learning to network algorithm design, identify challenges and discuss limitations. We empirically demonstrate the potential of machine learning network algorithms in two case studies, namely the embedding of virtual networks (a packing optimization problem) and k-center facility location (a covering optimization problem), using a prototype implementation.
Verification of the Effectiveness to Monitor Darknet across Multiple Organizations (2021)

Researchers and network operators regularly monitor unused Internet address space called the darknet to understand malicious activities on the Internet such as malware infections, DDoS, and scanning to find vulnerable systems. The purpose of this study is to demonstrate the effectiveness of darknet monitoring across multiple organizations by conducting a detailed similarity analysis. In this paper, we analyze darknet data observed in two organizations in different industries and the first octet subnet range. We compared the results of the similarity analysis between intra-organization and inter-organization calculations by dividing the address space into multiple blocks so that one organization conducts similarity analysis in an intra-organization manner. The results show that the similarity of the source hosts is lower in the inter-organization calculation than in the intra-organization calculation. In addition, we monitor more source hosts in inter-organization. Moreover, this work also reports that the results differ depending on the destination ports/protocols. From the results obtained, we clarified the effectiveness of distributing the monitoring points of the darknet across multiple organizations.
Influence of partial agonist expression on CD8 T cell responses for non-self antigens (132.35) (2010)

Abstract Differences in affinity of TCR for peptide/MHC complex induced by single amino acid substitutions in the peptide dramatically alter recognition by T cell in the periphery. With H60 as an antigenic model, we investigated the influence of transgenic expression of natural H60 antigen (H60N Tg) or of H60 antigen with single amino acid substitution at position 4 to histidine (H60H Tg) on H60H- or H60N-specific CD8 T cell responses, respectively. Immunization of B6 female mice with splenocytes from male H60NTg or H60H Tg mice induced strong CD8 T cell responses against each epitope, H60N or H60H, in CD4 T cell help dependent ways. While the immunization with splenocytes from male H60H Tg induced proliferation of H60-specific CD8 T cell responses in the female H60N Tg mice, CD8 T cell response for H60H induced in female H60N Tg showed significant reduction in the magnitude of H60H-tetramer-binding CD8 T cells at the peak time. And differences in TCR V beta usages of H60H-reactive CD8 T cells were also found between in the female B6 female and female H60N Tg hosts. Our data suggest that expression of proteins with amino acid changes influences the antigen-specific CD8 T cell responses and repertoire of TCRS involved in the responses.
A first prototype of an endoscopically implantable gastrostimulator. (2013)

info:eu-repo/semantics/published
Detection and Pose Estimation of Piled Objects Using Ensemble of Tree Classifiers (2012)

To date, however, there has been only limited success in this longstanding problem (e.g., picking piled objects), and, to the best of our knowledge, existing algorithms (e.g., Drost, et al., 2010; Ulrich et al., 2009; Hinterstoisser et al., 2007) fall short of practical use in automatic assembly of electronic products composed of various parts with differing optical and surface properties as well as with differing shapes and sizes. We found that even the stateof-the-art, commercially available machine vision software cannot be practically used for picking such piles of parts with unknown pose and occlusion. Specifically, as exemplified in Figure 1 (b), for black (or white)-colored and untextured parts with some degree of complexity in shape, conventional methods turned out to be of little use.
An Improved Multiple-Shift Algorithm for Rapid Code Acquisition in Optical CDMA Systems (2007)

In this paper, a novel code acquisition algorithm called the improved multiple-shift (IMS) is proposed using optical orthogonal code (OOC) in optical code division multiple access (CDMA) systems. The IMS algorithm has similar process; yet better code acquisition performance compared with the conventional MS algorithm. We analyze the code acquisition performance of the IMS algorithm and compare the performance of the IMS algorithm with that of the MS algorithm, in the single user and multi-user environments via simulation.
Dental care for children fed by tube: a critical review (1999)

No guidelines for the oral care of children fed by tube have been published. Poor oral health (unrestored caries lesions, poor oral hygiene, dependence for oral care) and tube-feeding are associated with the development of aspiration pneumonia. Children fed by tube have abundant calculus, and low caries activity. The potential for dental erosion related to gastro-esophageal reflux and oral hypersensitivity is high. To optimize oral health and reduce the risk of aspiration pneumonia, this population should receive dental care at more frequent intervals than children fed orally. Modifications to dental procedures are suggested to minimize the risks associated with dental treatment. Evidence-based treatment guidelines are indicated to optimize dental care for children fed by tube.
The museum of pure form: system architecture (2002)

This article describes the architecture of the "museum of pure form", a virtual reality system where the user can interact, through the senses of touch and sight, with digital models of 3D art forms and sculptures. Two "museum of pure form" systems are currently being developed at PERCRO, Pisa, Italy. One of them will be placed inside several museums and art galleries around Europe and made available to people visiting such institutions. The second system will be tested inside a CAVE system. Moreover, some considerations on the control of the interfaces and on the haptic rendering are reported.
Chemical Processes in Vapor Deposition of Silicon: I . Deposition from and Etching by (1975)

Chemical processes occurring in the vapor deposition of silicon from and in the etching of silicon by were studied by means of a mass spectrometer coupled to the CVD reactor. This setup was successfully used for the qualitative and quantitative analysis of the composition of the vapor phase in the Si‐Cl‐H system. Species found in the vapor phase were, , , , , and , and their partial pressures were measured as a function of temperature, value of the Cl/H ratio, and of the chemical nature of the initial gaseous mixture entering the reactor. The experimentally determined partial pressures were compared with the equilibrium partial pressures of vapor species, calculated from the newest thermochemical data for the Si‐Cl‐H system. On the basis of these results we discuss the nature and the extent of chemical processes in systems studied.
Navigation Surgery Using an Open MR System (2004)

Under real-time MR image navigation using a double-donut type open MR system, various surgical procedures, such as microwave thermocoagulation therapy of liver tumors, have been carried out for 4.5 years. We have developed new MR compatible surgical instruments and navigation software by ourselves. Such devices have been increased the availability of MR-guided procedures and quite effective for the accurate and safe treatment.
Supplementary Figure 4 from Overall Survival in Malignant Glioma Is Significantly Prolonged by Neurosurgical Delivery of Etoposide and Temozolomide from a Thermo-Responsive Biodegradable Paste (2023)

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Nano processing for thin film disc applications (2004)

In this paper, we will discuss several of these nano-processing procedures and their merits and challenges for the fabrication of effective spin-transfer devices. Results of spin-transfer studies that have been made with these magnetic nanopillars.
Near-Infrared Fluorescent Probe for Imaging of Pancreatic β Cells (2010)

The ability to image and ultimately quantitate beta-cell mass in vivo will likely have far reaching implications in the study of diabetes biology, in the monitoring of disease progression or response to treatment, and for drug development. Here, using animal models, we report on the synthesis, characterization, and intravital microscopic imaging properties of a near-infrared fluorescent exendin-4 analogue with specificity for the GLP-1 receptor on beta cells (E4(K12)-Fl). The agent demonstrated subnanomolar EC(50) binding concentrations, with high specificity and binding that could be inhibited by GLP-1R agonists. Following intravenous administration to mice, pancreatic islets were readily distinguishable from exocrine pancreas, achieving target-to-background ratios within the pancreas of 6:1, as measured by intravital microscopy. Serial imaging revealed rapid accumulation kinetics (with initial signal within the islets detectable within 3 min and peak fluorescence within 20 min of injection), making this an ideal agent for in vivo imaging.
Prototyping parallel and distributed programs in PROTEUS. Technical report (1990)

Prototyping is an important technique in software development for early exploration and validation of requirements. When prototyping concurrent behavior, the authors must be able to embrace a wide spectrum of models used to construct parallel programs, reflecting a variety of underlying system architectures. In this paper we present Proteus, a language, suitable for prototyping parallel and distributed programs. Proteus starts with the high-level set-theoretic notations of SETL and REFINE. They then extend this base with the barrier-merge parallel construct, which partitions the variables used for communication in its shared memory model into shared and private sets. Each parallel process receives an independent copy of the private variables. These private copies are independently updated, and may be merged into the global state at specifiable barrier synchronization points: at these points a portion of the merged state may be reflected back into each private state. They envision a layered language structure to express the various programming models, such as communicating sequential processes and data-level parallelism, in terms of this common foundation. A common foundation also facilitates the prototyping of heterogeneous systems whose concurrent parts are programmed following different models.
Rottlerin induces apoptosis of HT29 colon carcinoma cells through NAG-1 upregulation via an ERK and p38 MAPK-dependent and PKC δ-independent mechanism (2012)

Rottlerin, a selective inhibitor of novel isoforms of protein kinase C δ (PKC δ), has been shown to exert multiple effects on cancer cells, including inhibition of cell proliferation and migration. However, the molecular mechanisms responsible for these effects are not fully understood. We found that rottlerin dramatically induced non-steroidal anti-inflammatory drug activated gene-1 (NAG-1) expression in both p53 wild-type and p53-null cancer cell lines, suggesting that NAG-1 upregulation is a common response to rottlerin that occurs independently of p53 in multiple cell lines. Although rottlerin is known to inhibit PKC δ, PKC δ siRNA and overexpression of dominant-negative (DN)-PKC δ did not affect rottlerin-mediated induction of NAG-1. These results suggest that rottlerin induces NAG-1 upregulation via a PKC δ-independent pathway. We also observed that CHOP protein levels were significantly increased by rottlerin, but CHOP siRNA did not affect rottlerin-induced NAG-1 expression. In addition, we demonstrated the involvement of the mitogen-activated protein kinase (MAP kinase) signal transduction pathway in rottlerin-induced NAG-1 expression. Inhibitors of MEK (PD98059) and p38 MAP kinase (SB203580) prevented rottlerin-induced NAG-1 expression. Furthermore, we found that down-regulation of NAG-1 attenuated rottlerin-induced apoptosis. Collectively, the results of this study demonstrate, for the first time, that upregulation of NAG-1 contributes to rottlerin-induced apoptosis in cancer cells.
Roadway Data Representation and Application Development Phase III (2010)

The Florida Department of Transportation's Transportation Statistics (TranStat) Office would like to finalize the existing web-based Straight-Line Diagram (SLD)application, which was developed in the first phase of the research application development project in 2008 and 2009 and was improved in the second phase in 2010. The overall objective of the third phase of the application's development is to address production environment issues, improve operational characteristics and stabilize user schemes essential to realizing full use of capabilities such as: (1) application maintenance; (2) adjust application framework; (3) improvement of automatic scaling; and (4) application code of 508 compliance reviews.
Racial Disparities in Treatment Initiation and Outcomes of Chronic Hepatitis B Virus Infection in North America (2023)

In this observational study of chronic HBV, African American or Black participants were less likely than individuals of other races to meet treatment criteria, but among those who did, HBV treatment receipt did not differ significantly by race or socioeconomic factors. Not all eligible participants initiated treatment, but adverse liver outcomes were rare. These findings may not be generalizable to patients with chronic HBV receiving care in other settings.
Local Telephone Exchanges, Regulation, and Entry (1995)

This paper explores the relationship between technology and the policies that govern competition in the local telephone business. Analysis of competition policies requires a "long run" modeling perspective in which not only the entry and exit of firms are allowed but also allowed in changes in the nature of the investment in the underlying network technology such as network backbone and it s topology. This long run perspective requires a focus on the sources and conditions of joint production and public goods that exist in the production process and how they are influenced by the finance of the business and the constraints policies placed on firms to provide services that are not profitable.
The 2011 Summer Riots: Learning from History -Remembering ‘81 (2012)

Arguments that have emphasised the apparent meaninglessness and mindlessness of the 2011 riots rest on a number of assumptions and assertions. This includes for example the claim that such riots were fundamentally different on a number of levels compared to those of the past and particularly in relation to those of the 1980s. Whilst the latter have been viewed more sympathetically, with meanings and grievances now largely understood and accepted, and even seen as noble, the 2011 disturbances have been seen as lacking any real or legitimate grievances. By contradicting claims about the uniqueness of the recent riots (whilst also acknowledging important differences), it is possible to challenge assertions that firstly, the rioters did not have genuine grievances and secondly, that they should not be listened to. By examining the (qualified) similarities and continuities between riots past and present, we argue the case that it is likely that deep-seated grievances lay behind the 2011 riots that demands serious public and political engagement. Such perspective needs to stand in place of the dismissal that politicians were quick to offer, alongside their many instant diagnoses of the rioters’ conditions and the social evils they represent. The qualitative differences that do exist between the urban unrest of 1981 and the 2011 English riots reflect the historical specificities’ of these periods and the immediate material conditions within which each are grounded.
ChemInform Abstract: Reductive Coupling and Reductive Demethoxylation of Aromatic Dimethylacetals with SmI2/Trifluoroacetic Acid, SmI2/BF3×Et2O, or SmI2/H2O. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Myocardial infarction reduces cardiac nociceptive neurotransmission through the vagal ganglia (2022)

Myocardial infarction causes pathological changes in the autonomic nervous system, which exacerbate heart failure and predispose to fatal ventricular arrhythmias and sudden death. These changes are characterized by sympathetic activation and parasympathetic dysfunction (reduced vagal tone). Reasons for the central vagal withdrawal and, specifically, whether myocardial infarction causes changes in cardiac vagal afferent neurotransmission that then affect efferent tone, remain unknown. The objective of this study was to evaluate whether myocardial infarction causes changes in vagal neuronal afferent signaling. Using in vivo neural recordings from the inferior vagal (nodose) ganglia and immunohistochemical analyses, structural and functional alterations in vagal sensory neurons were characterized in a chronic porcine infarct model and compared with normal animals. Myocardial infarction caused an increase in the number of nociceptive neurons but a paradoxical decrease in functional nociceptive signaling. No changes in mechanosensitive neurons were observed. Notably, nociceptive neurons demonstrated an increase in GABAergic expression. Given that nociceptive signaling through the vagal ganglia increases efferent vagal tone, the results of this study suggest that a decrease in functional nociception, possibly due to an increase in expression of inhibitory neurotransmitters, may contribute to vagal withdrawal after myocardial infarction.
Using Nanowires To Extract Excitons from a Nanocrystal Solid (2011)

Synthetic methods yielding highly uniform colloidal semiconductor nanocrystals with controlled shapes and sizes are now available for many materials. These methods have enabled geometrical control of optical properties, which are difficult or impossible to achieve in conventional bulk solids. However, incorporating nanocrystals efficiently into photodetectors remains challenging because of the low charge carrier mobilities typical of nanocrystal solids. Here we present an approach based on exciton energy transfer from CdSe/CdS core/shell nanocrystals to embedded CdSe nanowires. By combining the wide electronic tunability of nanocrystals with the excellent one-dimensional charge transport characteristics obtainable in nanowires, we are able to increase photocurrent extraction from a nanocrystal solid by 2-3 orders of magnitude. Furthermore, we correlate local device morphology with optoelectronic functionality by measuring the local photocurrent response in a scanning confocal microscope. We also discuss how nancocrystal/nanowire hybrid devices could be used in particle detector systems.
Detection of small heterogeneities using diffuse photon density waves (1999)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text L. Montandon, D. Salzmann, and C. Depeursinge, "Detection of small heterogeneities using diffuse photon density waves," in Biomedical Optics, OSA Technical Digest (Optica Publishing Group, 1999), paper AMC5. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article