gebhart/patrepeval huggingface dataset:
Synthesis and Structure of a (Diphosphoxane)rhodium(I) Complex. Novel Reaction with CO To Liberate a Phosphinidene Oxide (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and Structure of a (Diphosphoxane)rhodium(I) Complex. Novel Reaction with CO To Liberate a Phosphinidene OxideKun Wang, Thomas J. Emge, and Alan S. GoldmanCite this: Organometallics 1994, 13, 5, 2135–2137Publication Date (Print):May 1, 1994Publication History Published online1 May 2002Published inissue 1 May 1994https://pubs.acs.org/doi/10.1021/om00017a088https://doi.org/10.1021/om00017a088research-articleACS PublicationsRequest reuse permissionsArticle Views127Altmetric-Citations15LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Continuous negative airway pressure “CNAP”: Novel nasal foreign body removal (2017)

&lt;p class="abstract"&gt;&lt;span lang="EN-IN"&gt;We report on a novel and innovative method used to extricate nasal foreign bodies in infants and young children– a common presentation in pediatric emergency care that can at times have potentially serious consequences. In the case of a three-year-old girl, ‘continuous negative airway pressure (CNAP)’ using a continuous positive airway pressure (CPAP) mask and a domestic vacuum cleaner, a nasal foreign body was removed quickly and effectively in a simple and painless procedure. While more cases are needed to confirm safety and efficacy, the principles underlying this technique could have great potential for future clinical use due to its simplicity and accessibility, particularly when compared to other techniques currently used in the home and in the emergency department.&lt;/span&gt;&lt;/p&gt;
A review of the literature for whole-body FDG PET in the management of patients with melanoma. (2000)

Our review suggests that improvements can be made to more effectively report the results of these FDG PET studies. The overall values determined through the meta-analysis indicate the potential benefits of using FDG PET as a diagnostic/management tool. Furthermore, these values should prove useful to assessing the cost effectiveness of utilizing FDG PET in the management of recurrent melanoma.
Biofilm dispersal: deciding when it is better to travel (2014)

Bacteria live predominantly in biofilms, and the internal signal cyclic diguanylate (c-di-GMP) is a universal signal that governs the formation and the dispersal of these communities. Pseudomonas aeruginosa is one of the most important reference systems for studying bacterial biofilms and contains numerous diguanylate cyclases (DGCs) for synthesizing c-di-GMP and phosphodiesterases (PDEs) for degrading c-di-GMP. However, few studies have discerned how cells in biofilms respond to their environment to regulate c-di-GMP concentrations through this sophisticated network of enzymes. Basu Roy and Sauer (2014) provide insights on how cells disperse in response to an increase in nutrient levels. Their results show that the inner membrane protein NicD is a DGC that controls dispersal by sensing nutrient levels: when glutamate concentrations are increased, NicD is dephosphorylated, which increases c-di-GMP levels and leads to phosphorylation and processing of dispersal regulator BdlA. Processing of BdlA leads to activation of PDE DipA, which results in a net reduction of c-di-GMP and biofilm dispersal. These results suggest biofilm dispersal relies on surprisingly dynamic c-di-GMP concentrations as a result of a sophisticated interaction between DGCs and PDEs.
Guadecitabine increases response to combined anti-CTLA-4 and anti-PD-1 treatment in mouse melanoma in vivo by controlling T-cells, myeloid derived suppressor and NK cells (2023)

These results indicate Guadecitabine as a promising epigenetic drug to be added to ICBs therapy.
Spatiotemporal response of rat visual cortex during moving stimuli using Functional Ultrasound (fUS) Imaging (2016)

International audience
Evaluation of multiplex real‐time PCR for identifying dermatophytes in clinical samples—A multicentre study (2017)

The gold-standard method for dermatophyte identification involves direct microscopy and culture, which have inherent shortcomings. Only few molecular methods have been standardised for routine clinical work. This study aimed to develop and test a platform for identifying the most common dermatophytes in Israel using multiplex real-time polymerase chain reaction (RT-PCR). Specific primers were designed for the multiplex system (LightCycler 480) according to known cultures and validated by reference isolates. The dermatophyte detection rate was compared to smear and culture in 223 clinical samples obtained from a tertiary medical centre. Inconsistencies between methods were evaluated by sequencing. The RT-PCR was further evaluated in 200 community-based samples obtained from a health maintenance organisation and 103 military-personnel-based samples analysed at a central laboratory. In hospital-based clinical samples, complete concordance between methods was observed in 190 samples (85%; Kappa = 0.69). In most cases of non-concordance, sequencing was consistent with RT-PCR results. RT-PCR correctly identified all smear- and culture-positive cases in community and military-personnel samples. The results were available within 4 hours. The multiplex RT-PCR platform is a rapid and efficient method for identifying dermatophyte species in clinical samples and may serve as a first step in the diagnostic algorithm of superficial fungal infections.
MEF2D haploinsufficiency downregulates the NRF2 pathway and renders photoreceptors susceptible to light-induced oxidative stress (2017)

Gaining mechanistic insight into interaction between causative factors of complex multifactorial diseases involving photoreceptor damage might aid in devising effective therapies. Oxidative stress is one of the potential unifying mechanisms for interplay between genetic and environmental factors that contribute to photoreceptor pathology. Interestingly, the transcription factor myocyte enhancer factor 2d (MEF2D) is known to be important in photoreceptor survival, as knockout of this transcription factor results in loss of photoreceptors in mice. Here, using a mild light-induced retinal degeneration model, we show that the diminished MEF2D transcriptional activity in <i>Mef2d</i><sup>+/-</sup> retina is further reduced under photostimulation-induced oxidative stress. Reactive oxygen species cause an aberrant redox modification on MEF2D, consequently inhibiting transcription of its downstream target, nuclear factor (erythroid-derived 2)-like 2 (NRF2). NRF2 is a master regulator of phase II antiinflammatory and antioxidant gene expression. In the <i>Mef2d</i> heterozygous mouse retina, NRF2 is not up-regulated to a normal degree in the face of light-induced oxidative stress, contributing to accelerated photoreceptor cell death. Furthermore, to combat this injury, we found that activation of the endogenous NRF2 pathway using proelectrophilic drugs rescues photoreceptors from photo-induced oxidative stress and may therefore represent a viable treatment for oxidative stress-induced photoreceptor degeneration, which is thought to contribute to some forms of retinitis pigmentosa and age-related macular degeneration.
Imbibitional Damage and Desiccation Tolerance of Wild Rice (Zizania palustris) Seeds (1992)

Seeds (caryopses) of North American wild rice (Zizania palustris var. interior), a temperate aquatic grass, have been reported to lose viability when desiccated (i.e. to be ‘recalcitrant’ or ‘homoiohydrous’). They are also deeply dormant at maturity and require as much as six months of stratification to break dormancy. It has been suggested that wild rice seed may have been misclassified as recalcitrant in some experiments due to the presence of dormancy. We report here that wild rice seeds can survive desiccation to seed and cmbryonic axis moisture contents as low as 6–8% (fresh weight basis). However, maximum survival of desiccation to these low moisture contents is possible only if dehydration occurs at temperatures ≥25°C and a slow imbibition period (3 weeks minimum) is allowed at temperatures between 10 and 25°C prior to stratification or dormancy-breaking treatments. The reduction in survival of dehydration at temperatures <25°C appears to occur only when embryonic axis moisture contents are reduced below about 8%. We also show that various techniques to assess viability of dry dormant seeds (moisture contents <30%), such as tetrazolium tests or scarifying the pericarp above the embryo, can cause a reproducible loss of viability due to imbibitional damage that has previously been interpreted as intolerance of desiccation. Most reports of the desiccation intolerance of wild rice seeds can be explained on the basis of the temperatures of dehydration or rehydration, failure to break dormancy, or imbibitional injury during viability testing. The successful dehydration and rehydration of wild rice seeds has important practical implications for seed storage and germplasm preservation. In addition, the temperature dependence of desiccation tolerance in wild rice seeds represents a novel relationship between seed viability, temperature, and moisture content.
Inducing Oxygen Vacancies to Modulate Ignition Threshold of Nanothermites (2022)

Many characteristics of metal oxides are governed by defect chemistry. As a result, defect engineering has become an effective strategy to modulate the electrical, optical, and mechanical properties of metal oxides. As the most commonly used oxidizers in nanothermite systems, metal oxides offer an opportunity to manipulate nanothermite reactions from a fundamental, atomic-scale, defect structure aspect. However, the challenge lies in the complexity of nanothermite reactions that requires shifting defect equilibria without introducing other variations. In this work, we choose a model oxidizer Co3O4 for aluminum-based nanothermite systems due to its easily tunable oxygen nonstoichiometry. Utilizing a soft chemistry reduction process, oxygen vacancies are created in Co3O4 with minimal structural disturbance. Ignition threshold is used as a metric to probe the effect of oxygen defects. The results show an inverse correlation between the ignition temperature of Al/Co3O4 nanothermites and oxygen vacancy content in Co3O4. The evolved species analyzed by temperature-jump time-of-flight mass spectrometry (T-jump TOFMS) indicates that the ignition is likely limited by the availability of sufficient gas-phase oxygen species, the production of which can be facilitated by oxygen vacancies.
Crohn's disease in the Chinese population (1994)

Although there is a general increased incidence of Crohn's disease in the Western world, we too are beginning to see more cases in the Far East. Nevertheless, gastrointestinal infection with bacteria and/or parasites should still be carefully excluded in these countries.
IBM Research TRECVID-2006 Video Retrieval System (2006)

In this paper, we describe the IBM Research system for indexing, analysis, and retrieval of video as applied to the TREC-2007 video retrieval benchmark. This year, focus of the system improvement was on cross-domain learning, automation, scalability, and interactive search.
Ordering Kinetics and Alignment of Block Copolymer Lamellae under Shear Flow (1999)

The effect of large-amplitude oscillatory shear flow on a concentrated block copolymer solution with lamellar order was studied by in-situ small-angle neutron scattering. Microstructural changes were studied as a function of temperature, frequency of the oscillatory flow field, and thermal history prior to turning on the shear field. We find that the alignment path depends mainly on thermal history prior to turning on the shear field and is independent of frequency and temperature. At long times, the lamellae were aligned parallel to the shearing plates, regardless of frequency, temperature, and thermal history. We refer to this as the parallel orientation. Monotonic changes from the unaligned to the aligned state were found when the shear field was turned on after the sample was completely ordered. The alignment kinetics, in this case, occurs in two stages. The first stage consists of a rapid rotation of the grains so that the lamellar normals lie in the velocity gradient−vorticity plane. This is followed by a slower process wherein the lamellar normals get increasingly localized in the velocity gradient direction. We also studied ordering kinetics under shear, by turning on the shear field before significant ordering had taken place. In this case, the first stage of ordering resulted in the formation of lamellae aligned perpendicular to the shearing plates in addition to the parallel lamellae, regardless of temperature and frequency. Eventually the perpendicular lamellae were transformed to parallel lamellae via an undulation instability.
Evaluation Experiments On Holographic Storage Of Binary Data In Electro-Optic Crystals (1981)

From extensive measurements of diffracted power distributions from binary-data-page holograms, the probabilities of bit error are calculated to be as low as 5 x 10-8 for volume Fourier transform holograms in iron-doped lithium niobate. Results are determined as a function of reference beam angular position for different diffraction efficiencies, for the angularly multiplexed superposition of holograms with dif-ferent angular separations, and for different displacements of the Fourier transform plane from the electro-optic crystal.
Silicon-germanium for photonic applications (2015)

Germanium and silicon-germanium have become crucial materials in the silicon photonics field, enabling devices such as high speed photodetectors and high speed modulators to be realised.<br/><br/>In order to fabricate efficient and cost effective silicon photonic devices, high quality epitaxial germanium and silicon-germanium growth on silicon, or silicon-on-insulator, is of the utmost importance.<br/><br/>In this project, localised single crystal, defect free silicon-germanium on insulator islands have been grown using a rapid melt growth technique. Tailored tree-like structures have been used to modify the cooling rate of the structures during re-growth from the liquid phase. The resulting silicon-germanium composition profiles have been characterised using Raman spectroscopy.<br/><br/>Using these tailored tree-like structures, uniform composition silicon- germanium strips have been grown, which is the first time this has been demonstrated using a rapid melt growth technique. Additionally, the ability to locally tune the composition of adjacent silicon-germanium strips has been shown. This enables the possibility of growing a whole range of uniform composition strips, using only a single growth step and a single anneal step, for, amongst others, wavelength division multiplexing applications.<br/><br/>Epitaxial growth of germanium on silicon by plasma enhanced chemical vapour deposition has also been studied. Single crystal layers with a defect density of approximately 3.3x10<sup>8</sup> cm<sup>-2</sup> and root mean square surface roughness of 3.5 nm have been demonstrated. It has also been shown that the defect density, surface roughness and crystallinity are all improved with a two minutes, 600 °C anneal.<br/><br/>This material has been used to fabricate 12.5 Gbit/s, 0.1 A/W waveguide integrated, zero bias photodetectors for 1550 nm silicon photonics applications, and also, germanium-on-silicon waveguides for mid-infrared silicon photonics applications.
Alopecia and cutaneous atrophy due to occipital nerve block containing steroids (2022)

Greater occipital nerve blockade is regularly used to treat primary headache disorders, including migraines and cluster headaches.1,2 Infiltration of the greater occipital nerve is particularly effective for patients with tenderness over the nerve.3 Corticosteroid use is not standard during these procedures; however, their use can induce prolonged relief.1 Various doses and preparations are employed in practice, often involving a combined injection of local anesthetics and corticosteroids around the occipital nerve.
Exploiting in situ NMR to monitor the formation of a metal–organic framework (2020)

The formation processes of metal-organic frameworks are becoming more widely researched using <i>in situ</i> techniques, although there remains a scarcity of NMR studies in this field. In this work, the synthesis of framework MFM-500(Ni) has been investigated using an <i>in situ</i> NMR strategy that provides information on the time-evolution of the reaction and crystallization process. In our <i>in situ</i> NMR study of MFM-500(Ni) formation, liquid-phase <sup>1</sup>H NMR data recorded as a function of time at fixed temperatures (between 60 and 100 °C) afford qualitative information on the solution-phase processes and quantitative information on the kinetics of crystallization, allowing the activation energies for nucleation (61.4 ± 9.7 kJ mol<sup>-1</sup>) and growth (72.9 ± 8.6 kJ mol<sup>-1</sup>) to be determined. <i>Ex situ</i> small-angle X-ray scattering studies (at 80 °C) provide complementary nanoscale information on the rapid self-assembly prior to MOF crystallization and <i>in situ</i> powder X-ray diffraction confirms that the only crystalline phase present during the reaction (at 90 °C) is phase-pure MFM-500(Ni). This work demonstrates that <i>in situ</i> NMR experiments can shed new light on MOF synthesis, opening up the technique to provide better understanding of how MOFs are formed.
Role of Escherichia Coli Adhesins in Urethral Colonization of Catheterized Patients (1988)

Escherichia coli is a major cause of catheter-associated urinary tract infection and frequently colonizes the urethra prior to invading the urinary tract. Bacterial pili, filamentous protein cell surface-associated appendages, have been shown to mediate colonization of epithelial cells. Pili associated adhesins can be detected in vitro by their ability to mediate bacterial hemagglutination of erythrocytes. We have assessed the role of bacterial adhesins in supporting urethral colonization by determining the hemagglutination reactions of 56 E. coli isolates from the urethra of patients with indwelling urethral catheters. The adhesin detected most frequently was the type 1 mannose-sensitive hemagglutinin (43%), and 43% of isolates failed to hemagglutinate guinea pig or human erythrocytes. E. coli hemagglutinins were no more common on urethral isolates from patients that were persistently colonized (E. coli present 70% of the time catheterized), than from those that were transiently colonized (E. coli present 30% of the time catheterized). Analysis of the HA reactions and DNA plasmid profiles of multiple isolates from persistently colonized patients suggested that the E. coli strain colonizing the urethra changed over time. The data suggest that bacterial colonization of the urethra is mediated in part by adhesins and changes over time.
Laser Raman spectroscopy of supported vanadium oxide catalysts (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTLaser Raman spectroscopy of supported vanadium oxide catalystsGregory T. Went, S. Ted. Oyama, and Alexis T. BellCite this: J. Phys. Chem. 1990, 94, 10, 4240–4246Publication Date (Print):May 1, 1990Publication History Published online1 May 2002Published inissue 1 May 1990https://pubs.acs.org/doi/10.1021/j100373a067https://doi.org/10.1021/j100373a067research-articleACS PublicationsRequest reuse permissionsArticle Views2334Altmetric-Citations349LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access options Get e-Alerts
False-negative fluorine-18 fluorodeoxyglucose positron emission tomography of a malignant peripheral nerve sheath tumor arising from a plexiform neurofibroma in the setting of neurofibromatosis type 1. (2011)

Development of malignant peripheral nerve sheath tumors (MPNSTs) is a recognized complication in patients with neurofibromatosis type 1 (NF1). Differentiating benign from malignant lesions can be a difficult clinical problem. Positron emission tomography (PET) is an established method for making this differentiation with a high degree of sensitivity and specificity. There are several reports showing that fluorine-18 fluorodeoxyglucose (FDG) PET is an effective imaging modality for detecting malignant transformation with a sensitivity nearing 100%. There are very few reports of false-negative 18F-FDG PET in a patient with an MPNST. This case report describes a woman with NF1 and a grade 3 MPNST and a negative PET scan. Identification of malignant transformation in NF is a significant clinical challenge. It is important to recognize the potential limitations of 18F-FDG PET in these patients.