gebhart/patrepeval huggingface dataset:
Personalized Classifier for Food Image Recognition (2018)

Currently, food image recognition tasks are evaluated against fixed datasets. However, in real-world conditions, there are cases in which the number of samples in each class continues to increase and samples from novel classes appear. In particular, dynamic datasets in which each individual user creates samples and continues the updating process often has content that varies considerably between different users, and the number of samples per person is very limited. A single classifier common to all users cannot handle such dynamic data. Bridging the gap between the laboratory environment and the real world has not yet been accomplished on a large scale. Personalizing a classifier incrementally for each user is a promising way to do this. In this paper, we address the personalization problem, which involves adapting to the user's domain incrementally using a very limited number of samples. We propose a simple yet effective personalization framework, which is a combination of the nearest class mean classifier and the 1-nearest neighbor classifier based on deep features. To conduct realistic experiments, we made use of a new dataset of daily food images collected by a food-logging application. Experimental results show that our proposed method significantly outperforms existing methods.
Reductions of conjugated carbonyl compounds with copper hydride - preparative and mechanistic aspects (1977)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTReductions of conjugated carbonyl compounds with copper hydride - preparative and mechanistic aspectsM. F. Semmelhack, R. D. Stauffer, and A. YamashitaCite this: J. Org. Chem. 1977, 42, 19, 3180–3188Publication Date (Print):September 1, 1977Publication History Published online1 May 2002Published inissue 1 September 1977https://pubs.acs.org/doi/10.1021/jo00439a015https://doi.org/10.1021/jo00439a015research-articleACS PublicationsRequest reuse permissionsArticle Views1537Altmetric-Citations103LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Slambede - hvordan håndterer vi dem? (2010)

Udgivelsesdato: 1 februar
In vivo phosphorylation states and kinase activities of transforming p60c-src mutants. (1989)

To further investigate regulation of p60src by tyrosine phosphorylation, the in vivo phosphorylation states and kinase activities of transforming mutants derived from p60c-src were examined. One set of six in vitro recombinants encoded chimeric proteins containing the carboxyl terminus of chicken p60c-src (including Tyr 527) in combination with various isolated amino acid substitutions present in p60v-src. Another set of seven viral isolates were randomly selected from soft-agar colonies infected with replicating retroviruses that originally encoded normal p60c-src. Results show that mutations at multiple sites throughout amino- and carboxy-terminal domains are sufficient to alter the in vivo phosphorylation state and kinase activity of p60c-src. Moreover, all of the transforming p60c-src mutants exhibited elevated in vivo kinase activities, as assayed by immune blot analysis of cellular proteins using antibodies to phosphotyrosine, which correlated well with enhanced auto-phosphorylation at Tyr 416. By contrast, Tyr 527 phosphorylation in the transforming mutants varied from low to high levels that were correlated to a limited extent with levels of in vivo kinase activities. Taken together, results suggest that, in addition to complete dephosphorylation of Tyr 527, other mechanisms contribute to p60c-src activation.
Authoring and Deploying Business Policies Dynamically for Compliance Monitoring (2011)

A policy authoring tool is integrated into a business provenance management system for dynamically authoring, deploying and monitoring compliance. The policy authoring tool enables creation of business rules in the language business people understand and deploys them into a rule engine. Once the policy is deployed, the compliance of process execution traces stored in a business provenance management system can be checked against these rules. Salient features of the solution architecture, including semantic mapping of IT terminology into business vocabulary and transforming business rules into key control points in the compliance checking system, are explained.
Magnetic properties and their relation to the no-load noise and no-load losses of large power transformers (2017)

The performance of the no-load losses and core noise of large power transformers (LPT) can be attributed to the magnetic properties of the deployed grain-oriented electrical steel (GOES) material. Measurements of different GOES materials have led to findings about their performance. Four LPT cores, each with a mass of 40 metric tons, were manufactured out of 187 GOES coils with the same material grade but with different properties. Before the transformer cores were manufactured, each of the deployed GOES coils was measured with an in-house coil measurement system (CMS) to obtain the specific power losses and the magnetostriction. This paper shows a first comparison between the measured GOES coils magnetic properties and LPTs. First, the measured magnetostriction of the GOES coils and their predictability on core noise of the LPTs are evaluated. In addition, the assessment of the GOES coils specific power losses and the no-load losses of the LPT units are shown.
Tet2-mediated clonal hematopoiesis in nonconditioned mice accelerates age-associated cardiac dysfunction (2020)

Clonal hematopoiesis of indeterminate potential is prevalent in elderly individuals and associated with increased risks of all-cause mortality and cardiovascular disease. However, mouse models to study the dynamics of clonal hematopoiesis and its consequences on the cardiovascular system under homeostatic conditions are lacking. We developed a model of clonal hematopoiesis using adoptive transfer of unfractionated ten-eleven translocation 2-mutant (Tet2-mutant) bone marrow cells into nonirradiated mice. Consistent with age-related clonal hematopoiesis observed in humans, these mice displayed a progressive expansion of Tet2-deficient cells in multiple hematopoietic stem and progenitor cell fractions and blood cell lineages. The expansion of the Tet2-mutant fraction was also observed in bone marrow-derived CCR2+ myeloid cell populations within the heart, but there was a negligible impact on the yolk sac-derived CCR2- cardiac-resident macrophage population. Transcriptome profiling revealed an enhanced inflammatory signature in the donor-derived macrophages isolated from the heart. Mice receiving Tet2-deficient bone marrow cells spontaneously developed age-related cardiac dysfunction characterized by greater hypertrophy and fibrosis. Altogether, we show that Tet2-mediated hematopoiesis contributes to cardiac dysfunction in a nonconditioned setting that faithfully models human clonal hematopoiesis in unperturbed bone marrow. Our data support clinical findings that clonal hematopoiesis per se may contribute to diminished health span.
Ependymal cell maturation is heterogeneous and ongoing in the mouse spinal cord and dynamically regulated in response to injury (2022)

Summary The spinal cord neural stem cell potential resides within the ependymal cells lining the central canal. These cells are, however, heterogeneous, and we know little about the biological diversity this represents. Here we use single-cell RNA-sequencing to profile adult mouse spinal cord ependymal cells. We uncover transcriptomes of known subtypes and a new mature ependymal cell state, that becomes more prominent with age. Comparison of ependymal cell transcriptomes from the brain and spinal cord revealed that ongoing cell maturation distinguishes spinal cord ependymal cells from their postmitotic brain counterparts. Using an ex vivo model of spinal cord injury, we show that ependymal cell maturation is reversible but also highly regulated. We revisit ependymal cell identities in adult human spinal cord and uncover evidence for their maturation and surprising ventralisation with age. This first in-depth characterisation of spinal cord ependymal cells paves the way to manipulation of distinct ependymal subtypes, provides insights into ependymal cell maturation dynamics and informs strategies for coaxing ependymal cell-driven spinal cord repair.
10702 Strain Measurement Properties by Small Type Sensor Using Oscillator Circuit (2015)

New type of strain sensor using a CMOS inverter oscillator circuit has been developed. This type sensor can omit an amplifier because a counting device measures frequency changes of circuit voltage output caused by resistance changes of a strain gauge. In this study, the authors manufactured one small prototype strain sensor using a CMOS inverter oscillator circuit. Characteristics and measurement accuracy of this small type sensor were confirmed through static tensile tests of specimens. The test results showed that the same level of accuracy as conventional sensor has been achieved by this small type sensor.
Supplementary Figure 4 from Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion (2023)

Supplementary Figure 4 from Paxillin Is a Target for Somatic Mutations in Lung Cancer: Implications for Cell Growth and Invasion
Localized audio watermarking technique robust against time-scale modification (2006)

Synchronization attacks like random cropping and time-scale modification are very challenging problems to audio watermarking techniques. To combat these attacks, a novel content-dependent localized robust audio watermarking scheme is proposed. The basic idea is to first select steady high-energy local regions that represent music edges like note attacks, transitions or drum sounds by using different methods, then embed the watermark in these regions. Such regions are of great importance to the understanding of music and will not be changed much for maintaining high auditory quality. In this way, the embedded watermark has the potential to escape all kinds of distortions. Experimental results show strong robustness against common audio signal processing, time-domain synchronization attacks, and most distortions introduced in Stirmark for Audio.
Stereoselective Reduction of δ‐Hydroxy‐β‐ketoesters (1986)

Abstract The reduction of δ‐hydroxy‐β‐ketoesters 1 was investigated with three different reducing agents. In several instances, high selectivity in favor of syn ‐1,3‐diols was observed.
Characterization of a Ryanodine Receptor inPeriplaneta Americana (1997)

Specific binding sites for the alkaloid ryanodine were characterized in membrane preparations from sarcoplasmatic reticulum of Periplaneta americana skeletal muscle. Binding of [3H]ryanodine was optimal at pH 8 and at CaCl2 concentration of about 300 mumol l-1. The Ca-chelating agents EGTA (100 mumol l-1) and EDTA (100 mumol l-1) abolished 95% and 90% of the [3H]ryanodine binding respectively. Preincubation with Ca2+ (100 mumol l-1) restored the ryanodine binding in presence of up to 300 mumol l-1 EGTA. Radioligand binding experiments showed one class of high affinity binding sites for ryanodine. Determination of rate constants revealed 7.05 x 10(6) l mol-1 min-1 for associating and 3.77 x 10(-3) min-1 for the dissociating [3H]ryanodine ryanodine receptor complex. Solubility of the ryanodine receptor was examined with different anionic, non-ionic and zwitterionic detergents. Best solubilization results of "calcium release channel" of cockroach muscle membrane preparations were obtained with the detergent CHAPS in a concentration of 5 mg ml-1.
A novel pathophysiologic link between upper and lower airways in patients with chronic rhinosinusitis: Association of sputum periostin levels with upper airway inflammation and olfactory function (2020)

This study was registered on the UMIN Clinical Trials Registry (Registry ID UMIN000018672).
Silicon and Germanium Mid-Infrared Optical Modulators (2018)

In this paper, we report our recent results on mid-infrared silicon and germanium based optical modulators. SOI and GOS modulators operating at --2 and --3.8 μm have been designed, fabricated and characterized. Both depletion and injection types of modulators have been realized.
Evidence for Induction of Interferon-α and Interferon-β in Retinal Glial Cells of Müller (1997)

Studies were performed to determine if retinal glial cells of Müller transcribe the genes for interferon-alpha (IFNalpha) or IFNbeta upon exposure to virus. Responses to herpes simplex virus type 1 (HSV-1) were tested with cultured murine Müller cells and, in vivo, with retinas obtained after bilateral injection of either HSV-1 or buffer into the anterior chamber of the eyes of BALB/c mice. Induction of IFN transcription and relative temporal changes in transcript levels occurred over time after either in vitro or in vivo exposure to HSV-1. Transcription of both IFN genes was induced in cultured glia within 1 hr after exposure to virus. IFN transcripts were detected in retinas by 24 hr postinfection and these were maximal at 3 days. By in situ hybridization (ISH), IFNalpha2 mRNA localized to focal areas in the intact retinas of virus-injected eyes and was consistent with our previous report of a transient, focal appearance of viral antigens in those retinas. Uninfected cells and ocular tissues were negative for IFN transcripts. Combined ISH and immunohistochemistry on retinal impression smears confirmed that glial fibrillary acidic protein-positive Müller cells are an intraretinal source of IFNalpha and IFNbeta transcripts after ocular exposure to HSV-1. Our results support a role for Muller cells as participants in intraretinal antiviral or immunomodulatory responses via type 1 IFN production and may have implications for future therapeutic interventions.
Arthroscopic decompression of a ganglion cyst causing suprascapular nerve compression (1996)

Ganglion cysts causing suprascapular nerve compression are an uncommon cause of suprascapular nerve compression. The advent of magnetic resonance imaging (MRI) and its application in patients with shoulder pain has improved the ability to diagnose cystic lesions causing extrinsic compression of the suprascapular nerve. Traditionally, treatment of suprascapular nerve compression by a ganglion cyst has required open cyst excision through either a deltoid and infraspinatus muscle takedown or a muscle splitting approach. We present three cases of suprascapular nerve compression by a ganglion cyst in which the cyst was decompressed arthroscopically. In each case the patient's symptoms resolved after arthroscopic cyst decompression, and a postoperative MRI does not demonstrate reaccumulation of the cyst fluid. Arthroscopic ganglion cyst decompression is a well-tolerated approach to this problem that avoids the morbidity of an open surgical procedure. The absence of recurrent cyst formation combined with resolution of the symptoms attests to the success of this method.
An Edge-Preserving Adaptive Bilateral Filter Based on Sobel Operator for Improving Image Quality Over Compression Ratio (2017)

디지털 이미지를 외부에서 획득함에 있어 필연적으로 잡음이 발생하게 되며 이는 압축 효율을 떨어뜨리는 요소로 작용한다. 압축 효율을 높이기 위한 방법으로 잡음은 제거하면서 시각에 민감한 엣지는 보존하기 위한 필터 개발은 이미지 처리 분야에서 시대를 불문하고 중요한 이슈였다. C. Tomasi가 제안한 양방향 필터의 경우 연산의 간결함과 필터의 효용성으로 인하여 일반적으로 사용된 필터이나 픽셀 주변 문맥을 고려하지 않고 이미지 내의 모든 픽셀에 사용자가 입력한 변수들이 일괄적으로 적용되어 해당 픽셀에 적합한 변수를 적응적으로 적용하지는 못한다는 문제점이 발생한다. 본 논문은 각 픽셀을 중심으로 소벨 연산을 이용하여 주변의 복잡도를 정의하고 이미지의 화질을 극대화하는 양방향 필터의 변수와의 관계를 함수로 추정하고 이를 통해 변수를 적응적으로 선택하는 알고리즘을 제안한다. 실험에서는 기존의 양방향 필터뿐만 아니라 개선된 성능을 보이는 다른 알고리즘들보다 제안하는 방법이 같은 압축률 대비 PSNR도 뛰어날 뿐만 아니라 엣지 부분에서는 더욱 더 뛰어난 효과가 나타남을 결과를 통해 확인할 수 있다.
Inhibitors of pan-PI3K Signaling Synergize with BRAF or MEK Inhibitors to Prevent BRAF-Mutant Melanoma Cell Growth (2015)

BRAF and MEK inhibitors have improved outcomes for patients with BRAF-mutant melanoma, but their efficacy is limited by both intrinsic and acquired resistances. Activation of the PI3K pathway can mediate resistance to these agents, providing a strong rationale for combination therapy in melanoma. Here, a panel of nine low-passage human metastatic melanoma cell lines with BRAF mutations was tested in cell proliferation and protein expression assays for sensitivity to inhibitors of MEK (selumetinib) and BRAF (vemurafenib) as single agents and in combination with inhibitors of pan-PI3K (ZSTK474), pan-PI3K/mTOR (BEZ235), individual PI3K isoforms (p110α, A66; p110β, TGX-221; p110γ, AS-252424; p110δ, idelalisib), or mTORC1/2 (KU-0063794). Selumetinib and vemurafenib potently inhibited cell proliferation in all cell lines, especially in those that expressed low levels of phosphorylated AKT (pAKT). ZSTK474 and BEZ235 also inhibited cell proliferation in all cell lines and enhanced the antitumor activity of selumetinib and vemurafenib in the majority of lines by either interacting synergistically or additively to increase potency or by inducing cytotoxicity by significantly increasing the magnitude of cell growth inhibition. Furthermore, ZSTK474 or BEZ235 combined with selumetinib to produce robust inhibition of pERK, pAKT, and pS6 expression and synergistic inhibition of NZM20 tumor growth. The inhibitors of individual PI3K isoforms or mTORC1/2 were less effective at inhibiting cell proliferation either as single agents or in combination with selumetinib or vemurafenib, although KU-0063794 synergistically interacted with vemurafenib and increased the magnitude of cell growth inhibition with selumetinib or vemurafenib in certain cell lines. Overall, these results suggest that the sensitivity of BRAF-mutant melanoma cells to BRAF or MEK inhibitors is at least partly mediated by activation of the PI3K pathway and can be enhanced by combined inhibition of the BRAF/MEK and PI3K/mTOR signaling pathways.
Combining Derivative and Parametric Kernels for Speaker Verification (2009)

Support vector machine-based speaker verification (SV) has become a standard approach in recent years. These systems typically use dynamic kernels to handle the dynamic nature of the speech utterances. This paper shows that many of these kernels fall into one of two general classes, derivative and parametric kernels. The attributes of these classes are contrasted and the conditions under which the two forms of kernel are identical are described. By avoiding these conditions, gains may be obtained by combining derivative and parametric kernels. One combination strategy is to combine at the kernel level. This paper describes a maximum-margin-based scheme for learning kernel weights for the SV task. Various dynamic kernels and combinations were evaluated on the NIST 2002 SRE task, including derivative and parametric kernels based upon different model structures. The best overall performance was 7.78% EER achieved when combining five kernels.
Method and apparatus for millimeter-wave detection of thermal waves for materials evaluation (2023)

A method and apparatus for generating thermal waves in a sample and for measuring thermal inhomogeneities at subsurface levels using millimeter-wave radiometry. An intensity modulated heating source is oriented toward a narrow spot on the surface of a material sample and thermal radiation in a narrow volume of material around the spot is monitored using a millimeter-wave radiometer; the radiometer scans the sample point-by-point and a computer stores and displays in-phase and quadrature phase components of thermal radiations for each point on the scan. Alternatively, an intensity modulated heating source is oriented toward a relatively large surface area in a material sample and variations in thermal radiation within the full field of an antenna array are obtained using an aperture synthesis radiometer technique.
A fully digital fast convergence algorithm for nonlinearity correction in multistage ADC (2006)

This paper describes a fast digital background calibration algorithm for pipeline or cyclic analog-to-digital converters. The proposed method corrects for the finite gain/bandwidth of the interstage operational amplifier and for capacitor mismatch in multiplying digital-to-analog converters stages. The new algorithm, fast gain error correction, converges more than 100 times faster than other correlation-based correction techniques presented in literature. The high speed of convergence of the error estimation is due to the use of a polynomial interpolation that cancel the interference in the error estimation process caused by the input signal. This new method does not need any added analog circuitry, does not perturb the output samples, and requires only a digital finite-impulse response filter to implement the polynomial interpolation as opposed to existing fast converging correlation techniques.
Electromechanical and Electronic Integrated Harvester for Shoes Application (2017)

Energy harvesting allows making sensors or transmitters electrically autonomous. Several studies have been proposed but most cases lack electrical and mechanical parts integration and practical application purpose. Here, with the aim of supplying a Bluetooth step-counter placed in the sole of a training shoe, a complete system is presented. It consists of a magnetoinductive transducer embedded with an electronic interface for power conditioning and exploits only the energy recovered by the impact on the ground. A φ 27 × 16 mm cylindrical device containing the transducer, the electronic interface, the step-counter electronics, and the protective shell is developed. Energy recovery derives from the magnet-free oscillation following the shoe impact. The proposed interface exploits pulse-width modulation to perform transducer output rectification and to emulate optimal load impedance while charging a storage capacitor. Numerical and experimental analysis show effective optimal resistive load emulation and energy recovery gain of 2 compared with the standard ac-dc interface. Prototypes have been manufactured and tested. Considering a sample footstep, energy recovery is 360 μJ against 400 μJ dissipated on optimal resistor. Mean energy recovery over a complete run is 644 μJ/footstep. In spite of variable excitation, energy recovery at each footstep is larger than the required and allows the step-counter transmitting the information.