gebhart/patrepeval huggingface dataset:
An Experimental Evaluation of SiC Switches in Soft-Switching Converters (2013)

Soft-switching converters equipped with insulated gate bipolar transistors (IGBTs) in silicon (Si) have to be dimensioned with respect to additional losses due to the dynamic conduction losses originating from the conductivity modulation lag. Replacing the IGBTs with emerging silicon carbide (SiC) transistors could reduce not only the dynamic conduction losses but also other loss components of the IGBTs. In the present paper, therefore, several types of SiC transistors are compared to a state-of-the-art 1200-V Si IGBT. First, the conduction losses with sinusoidal current at a fixed amplitude (150 A) are investigated at different frequencies up to 200 kHz. It was found that the SiC transistors showed no signs of dynamic conduction losses in the studied frequency range. Second, the SiC transistors were compared to the Si IGBT in a realistic soft-switching converter test system. Using a calorimetric approach, it was found that all SiC transistors showed loss reductions of more than 50%. In some cases loss reductions of 65% were achieved even if the chip area of the SiC transistor was only 11% of that of the Si IGBT. It was concluded that by increasing the chip area to a third of the Si IGBT, the SiC vertical trench junction field-effect transistor could yield a loss reduction of approximately 90%. The reverse conduction capability of the channel of unipolar devices is also identified to be an important property for loss reductions. A majority of the new SiC devices are challenging from a gate/base driver point-of-view. This aspect must also be taken into consideration when making new designs of soft-switching converters using new SiC transistors.
Figure S2 from The Human CD38 Monoclonal Antibody Daratumumab Shows Antitumor Activity and Hampers Leukemia–Microenvironment Interactions in Chronic Lymphocytic Leukemia (2023)

&lt;p&gt;Figure S2. Effect of all-trans retinoic acid (ATRA) on daratumumab-induced CDC.CLL cells (n=6) were treated with 10nM ATRA or left untreated for 48h. CD38 expression was analyzed subsequently (CD19-FITC CD5-PECy5 CD38PE).&lt;/p&gt;
Wavelength division multiplexers/demultiplexers for optical interconnects in massively parallel processing (2003)

Communication between computing systems is recognized as the main limitation to increase the speed of all-electronic systems beyond levels currently achieved in existing supercomputers. Optical in- terconnects hold great promise in eliminating current communication bottlenecks because of properties that stem from optics inherent paral- lelism. Wavelength-division multiplexing (WDM) technology, by which multiple optical channels can be simultaneously transmitted at different wavelengths through a single optical transmission medium, is a useful means of making full use of optics parallelism in an application of inter- connects for massive parallel processing. We first briefly review the bottlenecks of electrical interconnects in massively parallel processing. Then we discuss the advantages of optical interconnects and present our approach of optoelectronic interconnects in massively parallel pro- cessing by WDM technology. We then review the working principles of wavelength division (de) multiplexers (WD(D)M) for optical interconnects in massively parallel processing and address the optical design issues of WD(D)Ms. Finally, we report experimental data of WD(D)Ms for this ap- plication. The devices exhibit low insertion loss, high reliability, and low cost. © 2003 Society of Photo-Optical Instrumentation Engineers.
Gene network inference via sparse structural equation modeling with genetic perturbations (2011)

Structural equation models (SEMs) have been recently proposed to infer gene regulatory network using gene expression data and genetic perturbations. However, lack of efficient inference method for SEMs prevents practical use of SEMs in the inference of relatively large gene networks. In this paper, relying on the sparsity of gene networks, we develop an efficient SEM-based method for inferring gene networks using both gene expression and expression quantitative trait locus (eQTL) data. Simulated tests demonstrate that the novel method significantly outperform state-of-the-art methods in the field.
“Like the Spring of a Beast”: Traumatological Haunting in “The Turn of the Screw” (2013)

Current debates surrounding canonical literary trauma theor focus on the unutterable nature of the traumatic experience adn how this is presented in the text. It is our contention that this critical position marginalises the centrality of the physical body as a marker of experience, that the body speaks as it endures.
Ambipolar Transport in the Smectic E Phase of 2‐Propyl‐5′′‐Hexynylterthiophene Derivative over a Wide Temperature Range (2008)

5-Hexyl-5''-hexynyl-2,2':5',2''-terthiophene exhibits the smectic E phase below 200 degrees C and does not crystallize when it is cooled to -100 degrees C. Between 200 and -100 degrees C, non-dispersive transport is observed for holes and electrons with time-of-flight spectroscopy. Over the entire temperature range, the electron mobility is approximately twice as high as that of the hole. The hole and electron transport characteristics in the smectic phase below 0 degrees C are explained by the Gaussian disorder model, which was proposed for amorphous organic semiconductors. The disorder parameters, sigma and Sigma, are almost the same for holes and electrons. However, the pre-exponential parameter mu(0) for the electron is twice as large as that for the hole, which can be attributed to the difference in the extension of the LUMO of the molecules. The energetic disorder sigma is primarily determined by the disorder in the orientation of the permanent dipoles of liquid crystal molecules.
Near-Infrared Quantum Dot Emission Enhanced by Stabilized Self-Assembled J-Aggregate Antennas (2017)

Enhancing photoluminescent emission (PL) in the near-infrared-infrared (NIR-IR) spectral region has broad applications from solar energy conversion to biological imaging. We show that self-assembled molecular dye J-aggregates (light-harvesting nanotubes, LHNs) can increase the PL emission of NIR PbS quantum dots (QDs) in both liquid and solid media more than 8-fold, promoted primarily by a long-range antenna effect and efficient Förster resonance energy transfer (FRET) from donor to acceptor. To create this composite material and preserve the optical properties of the nanocrystals, we performed an in situ ligand substitution followed by a functionalization reaction using click-chemistry. This resulted in PbS QDs soluble in an aqueous environment compatible with the molecular J-aggregates (LHNs). Theoretical and experimental results demonstrate that long-range diffusive exciton transport in LHNs enables efficient energy transfer to low concentrations of QDs despite there being no direct binding between molecular donors and QD acceptors. This suggests a broad application space for mixed light harvesting and photophysically active nanocomposite materials based on self-assembling molecular aggregates.
Tunable multi-wavelength SOA based linear cavity fiber laser source for optical communications applications (2011)

We propose and demonstrate a simple compact, inexpensive, SOA-based, multi-wavelength tunable (C- to L-band) fiber laser. A C-band design SOA is used, yet multi-wavelength operation either at the C or L-band region is accomplished by exploiting the gain compression phenomena of the SOA. We demonstrate that the wavelength tunability can be achieved either by inserting a variable attenuator inside the cavity of the laser or by changing the reflectivity of the mirrors. We exploit two different kinds of loop mirrors, a Sagnac and a Lyot-Sagnac loop mirror, which perform multiple functions. Stable multi-wavelength operation is achieved at room temperature without temperature compensation techniques, with measured power and the wavelength stability within <; ±0.5 dB and ±0.1 nm, respectively.
Novel heterocyclic syntheses from azomethine imides. 2-Unsubstituted diazetidinones (1968)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTNovel heterocyclic syntheses from azomethine imides. 2-Unsubstituted diazetidinonesRichard B. Greenwald and Edward C. TaylorCite this: J. Am. Chem. Soc. 1968, 90, 19, 5273–5274Publication Date (Print):September 1, 1968Publication History Published online1 May 2002Published inissue 1 September 1968https://pubs.acs.org/doi/10.1021/ja01021a042https://doi.org/10.1021/ja01021a042research-articleACS PublicationsRequest reuse permissionsArticle Views150Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Structure-based auto-calibration of RGB-D sensors (2016)

The readily available image and depth data from commodity RGB-D sensors has had tremendous impact in the robotics and computer vision community recently. To jointly leverage both modalities, the depth and image measurements need to be registered. Typical calibration approaches make use of artificial landmarks and special calibration targets. However, this is not feasible if on-line (re-)calibration is necessary or the sensor setup is inaccessible, e.g., for already captured datasets. Instead of using specific calibration patterns, we propose to leverage a sparse environment model as geometric prior for the calibration. Structure-from-motion or SLAM can provide such a sparse 3D scene model, and hence our approach allows for self-calibration without the need for any manual interaction. We validate our hypothesis by introducing an optimization that jointly minimizes the alignment error between the sparse map and all recorded depth maps. Since the accuracy of depth measurements is known to degrade considerably with scene depth, we account for this distortion via a spatially varying correction term. The evaluation of our approach demonstrates that we are able to compute an accurate extrinsic and intrinsic calibration, which for example allows dense 3D modeling at improved precision.
Molecular genetic characteristics of polyresistant Listeria monocytogenes strains and identification of new sequence types (2021)

<h3>ВВЕДЕНИЕ</h3> <i>Listeria monocytogenes</i> — возбудитель листериоза с показателем летальности до 21%. <h3>ЦЕЛЬ ИССЛЕДОВАНИЯ</h3> Изучение генотипов и фенотипов 30 штаммов <i>L. monocytogenes,</i> выделенных в 8 областях РФ в 2015—2018 гг. от людей, из пищевых продуктов и из сточных вод. <h3>МАТЕРИАЛ И МЕТОДЫ</h3> Проведено определение чувствительности штаммов к антимикробным препаратам, серотипирование, MLST-типирование, полногеномное секвенирование, идентификация генов антибиотикорезистентности, вирулентности и стрессоустойчивости, филогенетический анализ. <h3>РЕЗУЛЬТАТЫ</h3> Все штаммы отнесены к категории множественно лекарственно резистентных (MDR), выявлены гены резистентности <i>fosX</i>, <i>pbp-like</i>, <i>lin</i>, <i>norB</i> и <i>sul,</i> определены их аллельные профили. Идентифицировано 16 сиквенс-типов (ST) <i>L. monocytogenes</i>: четыре ST эволюционной линии I и двенадцать ST — эволюционной линии II, в том числе 13 ранее известных (ST1, ST2, ST5, ST7, ST9, ST14, ST16, ST20, ST26, ST121, ST155, ST425 и ST451) и три новых (ST1453, ST1455 и ST1454). Выявлено 5 серогрупп: 1-2a-3a, 1/2c-3c, 4b, 4a-4c и 1/2b-3b-7. В геномах всех штаммов идентифицированы острова патогенности LIPI-1 (<i>prfA, hly, plcA, plcB, mpl, actA</i>) и LIPI-2 (<i>inlABCJ</i>). Остров патогенности LIPI-3 (<i>llsAXGHBYDP</i>) выявлен у двух штаммов эволюционной линии I. Острова стрессоустойчивости SSI-1 и SSI-2 обнаружены у девяти и одного штаммов соответственно. Определены аллельные профили генов вирулентности и стрессоустойчивости. Филогенетический анализ выявил большое генетическое разнообразие штаммов. <h3>ЗАКЛЮЧЕНИЕ</h3> Выявлены MDR штаммы <i>L. monocytogenes,</i> относящиеся к широко распространенным высоковирулентным сиквенс-типам, описаны три новых сиквенс-типа.
Domino Cu‐Catalyzed CN Coupling/Hydroamidation: A Highly Efficient Synthesis of Nitrogen Heterocycles (2006)

Eins nach dem anderen: Hoch funktionalisierte Pyrrole und Pyrazole wurden mit einer Dominosequenz aus kupferkatalysierter C-N-Kupplung und Hydroamidierung synthetisiert. Die Anwendungsbreite der Methode ist beachtlich: Doppel- wie Dreifachbindung können verschiedenartige Substituenten tragen.
Ubiquitin in avian leukosis virus particles (1990)

We have identified unconjugated ubiquitin as a component of avian leukosis virus (ALV). Quantitation both by immunoblotting and by protein staining showed that ubiquitin makes up about 0.5% of total viral protein, corresponding to 100 molecules per virion. This level is about fivefold higher than the level of unconjugated ubiquitin in the cytosol, when expressed as a fraction of total protein. Other abundant low molecular weight proteins in the cytosol were not detected in virions, indicating that packaging occurs in a specific manner. A naturally occurring ALV mutant that lacks the env gene was found to package normal levels of ubiquitin, ruling out involvement of the viral glycoproteins as carriers of ubiquitin. We examined disrupted virus particles as well as lysates of infected cells for the presence of gag protein-ubiquitin conjugates. No conjugates could be detected, suggesting that ubiquitin does not enter virions linked to gag protein.
Differential Expression Profiling of the Hepatic Proteome in a Rat Model of Dioxin Resistance (2006)

One characteristic feature of acute 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) toxicity is dramatic interspecies and interstrain variability in sensitivity. This complicates dioxin risk assessment for humans. However, this variability also provides a means of characterizing mechanisms of dioxin toxicity. Long-Evans (Turku/AB) rats are orders of magnitude more susceptible to TCDD lethality than Han/Wistar (Kuopio) rats, and this difference constitutes a very useful model for identifying mechanisms of dioxin toxicity. We adopted a proteomic approach to identify the differential effects of TCDD exposure on liver protein expression in Han/Wistar rats as compared with Long-Evans rats. This allows determination of which, if any, protein markers are indicative of differences in dioxin susceptibility and/or responsible for conferring resistance. Differential protein expression in total liver protein was assessed using two-dimensional gel electrophoresis, computerized gel image analysis, in-gel digestion, and mass spectrometry. We observed significant changes in the abundance of several proteins, which fall into three general classes: (i) TCDD-independent and exclusively strain-specific (e.g. isoforms of the protein-disulfide isomerase A3, regucalcin, and agmatine ureohydrolase); (ii) strain-independent and only dependent on TCDD exposure (e.g. aldehyde dehydrogenase 3A1 and rat selenium-binding protein 2); (iii) dependent on both TCDD exposure and strain (e.g. oxidative stress-related proteins, apoptosis-inducing factor, and MAWD-binding protein). By integrating transcriptomic (microarray) data and genomic data (computational search of regulatory elements), we found that protein expression levels were mainly controlled at the level of transcription. These results reveal, for the first time, a subset of hepatic proteins that are differentially regulated in response to TCDD in a strain-specific manner. Some of these differential responses may play a role in establishing the major differences in TCDD response between these two strains of rats. As such, our work is expected to lead to new insights into the mechanism of TCDD toxicity and resistance.
Dual conformance index-based robotic arm placement and adaptation (1996)

A method to decide the placement and structural adaptation of a robotic arm with respect to a set of tasks is presented. Commercialized CAD/CAM tools mostly limit the layout criterion of robotized cells to the reachability of a task. They furnish little assistance for the selection of the tool, the arm, or its placement. A robot-task conformance index is shown to overcome these limitations. Four volume ratios define the index. They are taken over a robot ellipsoid, a task constraints ellipsoid, and a minimum containing and a maximum contained ellipsoid. The strict equivalence of the four ratios is proven. A “dual” computational sequence and the concept of relevant singularities are introduced. This “dual” computation is shown to equal the original conformance index outside relevant singularities. The index is applied to cases of increasing difficulty. Internal motions of joints within the null space of the Jacobian are typically used to maximize the index. The cases of simultaneous multitask optimization, tool definition, and robotic structure definition are addressed. Its usefulness for the design of the cell layout is exemplified. © 1996 John Wiley & Sons, Inc.
ChemInform Abstract: NOVEL TYPE OF ANALGESIC ‐ SYNTHESIS AND ANALGESIC ACTIVITY (1980)

Abstract Synthesis and Analgesic Activity.
Estimation of Formation Properties Using Multiprobe Formation Tester in Layered Reservoirs (1998)

Estimation of Formation Properties Using Multiprobe Formation Tester in Layered Reservoirs H. Badaam; H. Badaam A.D.C.O. Search for other works by this author on: This Site Google Scholar S. Al-Matroushi; S. Al-Matroushi A.D.C.O. Search for other works by this author on: This Site Google Scholar N. Young; N. Young A.D.C.O. Search for other works by this author on: This Site Google Scholar C. Ayan; C. Ayan Schlumberger Search for other works by this author on: This Site Google Scholar M. Mihçakan; M. Mihçakan Schlumberger Search for other works by this author on: This Site Google Scholar F.J. Kuchuk F.J. Kuchuk Schlumberger Search for other works by this author on: This Site Google Scholar Paper presented at the Abu Dhabi International Petroleum Exhibition and Conference, Abu Dhabi, United Arab Emirates, November 1998. Paper Number: SPE-49529-MS https://doi.org/10.2118/49529-MS Published: November 11 1998 Cite View This Citation Add to Citation Manager Share Icon Share Twitter LinkedIn Get Permissions Search Site Citation Badaam, H., Al-Matroushi, S., Young, N., Ayan, C., Mihçakan, M., and F.J. Kuchuk. "Estimation of Formation Properties Using Multiprobe Formation Tester in Layered Reservoirs." Paper presented at the Abu Dhabi International Petroleum Exhibition and Conference, Abu Dhabi, United Arab Emirates, November 1998. doi: https://doi.org/10.2118/49529-MS Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex Search Dropdown Menu nav search search input Search input auto suggest search filter All ContentAll ProceedingsSociety of Petroleum Engineers (SPE)Abu Dhabi International Petroleum Exhibition and Conference Search Advanced Search This paper was prepared for presentation at the 8th Abu Dhabi International Petroleum Exhibition and Conference held in Abu Dhabi, U.A.E., 11-14 October 1998. Keywords: vertical probe, formation property, pressure transient testing, formation testing, artificial intelligence, reservoir model, multi-probe formation tester, formation tester, probe, sink probe Subjects: Formation Evaluation & Management, Pressure transient analysis, Drillstem/well testing, Formation test analysis (e.g., wireline, LWD) This content is only available via PDF. 1998. Society of Petroleum Engineers You can access this article if you purchase or spend a download.
Inhibition of B cell–dependent lymphoid follicle formation prevents lymphocytic bronchiolitis after lung transplantation (2019)

Lung transplantation (LTx) is the only therapeutic option for many patients with chronic lung disease. However, long-term survival after LTx is severely compromised by chronic rejection (chronic lung allograft dysfunction [CLAD]), which affects 50% of recipients after 5 years. The underlying mechanisms for CLAD are poorly understood, largely due to a lack of clinically relevant animal models, but lymphocytic bronchiolitis is an early sign of CLAD. Here, we report that lymphocytic bronchiolitis occurs early in a long-term murine orthotopic LTx model, based on a single mismatch (grafts from HLA-A2:B6-knockin donors transplanted into B6 recipients). Lymphocytic bronchiolitis is followed by formation of B cell-dependent lymphoid follicles that induce adjacent bronchial epithelial cell dysfunction in a spatiotemporal fashion. B cell deficiency using recipient μMT-/- mice prevented intrapulmonary lymphoid follicle formation and lymphocytic bronchiolitis. Importantly, selective inhibition of the follicle-organizing receptor EBI2, using genetic deletion or pharmacologic inhibition, prevented functional and histological deterioration of mismatched lung grafts. In sum, we provided what we believe to be a mouse model of chronic rejection and lymphocytic bronchiolitis after LTx and identified intrapulmonary lymphoid follicle formation as a target for pharmacological intervention of long-term allograft dysfunction after LTx.
ChemInform Abstract: REACTION MECHANISM AND FACTORS INFLUENCING PHASE‐TRANSFER CATALYTIC ACTIVITY OF CROWN ETHERS BONDED TO A POLYSTYRENE MATRIX (1984)

Abstract Untersucht wird die phasentransferkatalytische Aktivität der aufeiner Polystyrolmatrix befindlichen Kronenether (I) gegenüber den Nucleophilen Y′ (Y: l, SCN, Br und CN) in den nucleophilen Modellreaktionen n‐Octyl‐O‐Mes + Y′ bzw. n‐OctyI‐Br + l".
Task selection for a multiscalar processor (2002)

The multiscalar architecture advocates a distributed processor organization and task-level speculation to exploit high degrees of instruction level parallelism (ILP) in sequential programs without impeding improvements in clock speeds. The main goal of this paper is to understand the key implications of the architectural features of distributed processor organization and task-level speculation for compiler task selection from the point of view of performance. We identify the fundamental performance issues to be: control flow speculation, data communication, data dependence speculation, load imbalance, and task overhead. We show that these issues are intimately related to a few key characteristics of tasks: task size, inter-task control flow, and inter-task data dependence. We describe compiler heuristics to select tasks with favorable characteristics. We report experimental results to show that the heuristics are successful in boosting overall performance by establishing larger ILP windows.