gebhart/patrepeval huggingface dataset:
ChemInform Abstract: Vicinal Diboronates in High Enantiomeric Purity Through Tandem Site‐Selective NHC—Cu‐Catalyzed Boron—Copper Additions to Terminal Alkynes. (2010)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Multistage receiver for differential space-time block codes (2004)

Tarokh's differential space-time block codes (DSTBC) can provide a full spatial diversity and be decoded without channel state information. The bit error rate performance of a conventional differential detection has 3-dB degradation compared to a coherent detection in a quasi-static fading channel. Differential detection experiences more degradation in a fast fading channel and error floor appears at high SNR. In [E. Chiavaccini and G.M. Vitetta, May 2002], an approximate maximum likelihood receiver was derived and it reduced the error floor significantly. In this paper, we modify the receiver in [E. Chiavaccini and G.M. Vitetta, May 2002] and apply the concept of multistage decision-directed estimator with intrablock-interference cancellation to obtain further improvement. The proposed receiver works efficiently at moderate to high SNR and at the fading rate between f/sub d/T = 0.02 and f/sub d/T = 0.07.
ChemInform Abstract: Convenient Ring‐Bromination of Alkylnaphthalenes Using N‐Bromosuccinimide in Acetonitrile. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Temporal Pattern Recognition with Delayed-Feedback Spin-Torque Nano-Oscillators (2019)

The recent demonstration of neuromorphic computing with spin-torque nano-oscillators has opened a path to energy efficient data processing. The success of this demonstration hinged on the intrinsic short-term memory of the oscillators. In this study, we extend the memory of the spin-torque nano-oscillators through time-delayed feedback. We leverage this extrinsic memory to increase the efficiency of solving pattern recognition tasks that require memory to discriminate different inputs. The large tunability of these non-linear oscillators allows us to control and optimize the delayed feedback memory using different operating conditions of applied current and magnetic field.
Supplementary Table from A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER<sup>+</sup> Breast Cancer (2023)

Supplementary Table from A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER&lt;sup&gt;+&lt;/sup&gt; Breast Cancer
Molecular genetics and the epidemiology of bipolar disorder (2001)

The methodologies of epidemiology and molecular genetics are complementary approaches to identifying risk factors in bipolar disorder. Genetic linkage studies have revealed several chromosomal loci likely to contain genes that increase the risk of bipolar disorder, but major uncertainties remain about the mode of inheritance of the condition and the definition of the phenotype. Epidemiological findings have contributed to both these areas and have led to new hypotheses about causation. For example, the analysis of variability of age at onset of bipolar disorder led to studies of anticipation and a possible role of dynamic DNA repeat sequence mutations. Future epidemiological studies that aim to identify risk factors for bipolar disorder at the population level will be able to measure the interactions of genome sequence variation with other risk factors in the domain of demography, childhood experiences, exposure to adversity and availability of social support.
Ultrasonic Flaw Detection in Model Railway Wheels (1971)

Feasibility studies for detection of flaws on the tread and in the plate of a railway wheel have been made using 14-scale models. With regard to flaw detection on the tread, both attenuation and pulse-echo methods have been employed, using surface waves. The acoustical equipment is similar to that previously described [D. E. Bray and R. D. Finch, J. Acoust. Soc. Amer. 47, 114 (1970)]. Flaws were simulated with machined channels inscribed to different depths on the tread. Changes in the attenuation of a surface-wave pulse with successive circuits of the tread could be detected in the presence of a flaw about 0.005 in. deep. This attenuation has been studied as a function of increasing flaw depth, number of flaws, and location of the flaw with respect to the source. With regard to flaw detection in the plate, some preliminary studies with two-dimensional models of a wheel cross section have been made. Here, the objective was to determine optimum frequency and transducer diameter to minimize rim reflections in favor of plate flaw echoes. [This work was supported by a Department of Transportation contract.]
Limits of Fusion and Depth Judgment in Stereoscopic Color Displays (1990)

The effective use of stereoscopic display systems is dependent, in part, on reliable data describing binocular fusion limits and the accuracy of depth discrimination for such visual display devices. These issues were addressed in three experiments, as were the effects of interocular cross talk. Results showed that limits of fusion were approximately 27.0 min arc for crossed disparity and 24.0 min arc for uncrossed disparity. Subjects were extremely accurate in distinguishing the relative distance among four groups of stimuli, were able to identify a pair of stimuli colocated at the same depth plane within each group, and were fairly accurate in scaling stimuli along the depth dimension. The mean error in using disparity as a depth cue was approximately 2.2 min arc. Interocular cross talk had little effect on fusion limits for 200-ms stimulus presentations but significantly affected fusion for longer (2 s) presentations that enabled vergence responses to be executed. Depth discrimination performance was essentially unaffected by interocular cross talk; however, cross talk significantly influenced subjective ratings of image quality and visual comfort.
CFD Analysis of Gas-Particle Heat Transfer in Gas-Phase Olefin Polymerizations (2016)

Computational fluid dynamics (CFD) is used to study the gas–particle heat transfer in gas-phase olefin polymerizations. Particularly, the effects of particle rotation on the gas–particle heat transfer coefficient and internal particle temperatures are evaluated, showing that particle rotation can exert a significant impact on observed temperature profiles, so that this effect should not be neglected during detailed CFD process simulations. As a consequence, particle rotation can lead to particle cooling and development of spherical gradient symmetry, validating the use of simpler modeling schemes that are based on reaction–diffusion in symmetrical spherical geometry.
Transfer Leaming in Automatic Speech Recognition for Serbian (2019)

In automatic speech recognition systems the training data used for system development and data expected to be obtained during the practical use of the system do not have to fit each other perfectly, but other similar data may be available. Transfer learning can help to exploit such similar data for training in order to boost the speech recognizer's performance in a certain domain. In this context, the paper presents the first application of transfer learning in speech recognition for the Serbian language. Several methods are proposed, with the goal of optimizing system performance on a specific part of the existing speech database for Serbian. The experimental results evaluated on a test set from the desired domain show significant improvement in both word error rate and character error rate.
A Complete Design of Smart Pad That Reduces Snoring (2023)

This paper presents integration of active noise control (ANC) systems with a smart pad to reduce the noise made by snoring. One reference microphone, two secondary speakers and two error microphones are used with a feedforward ANC algorithm in the smart pad design. Several smart functions including snore detection, quiet zone localization, and advanced audio integration are proposed. An effective way to satisfy the causality constraint of the feedforward ANC system is presented. The smart pad is independent of the pillow and is not in contact with the user; it is portable and is not a burden to the user during sleep. Several experiments are conducted to confirm the effectiveness of the smart pad when used on a full-size bed.
Supplementary Figure 3 from Targeting uPAR with Antagonistic Recombinant Human Antibodies in Aggressive Breast Cancer (2023)

&lt;p&gt;PDF file - 40K, Time activity curves for 111In-labeled 2G10 and 3C6 in MDA-MB-231 orthotopic xenograft tumor-bearing mice&lt;/p&gt;
Supplementary Table S1 from RhoB Determines Tumor Aggressiveness in a Murine EGFR<sup>L858R</sup>-Induced Adenocarcinoma Model and Is a Potential Prognostic Biomarker for Lepidic Lung Cancer (2023)

&lt;p&gt;Supplementary Table S1. Characteristics of patients in the three series&lt;/p&gt;
Marfan syndrome is closely linked to a marker on chromosome 15q1.5----q2.1. (1991)

Marfan syndrome is a systemic disorder of the connective tissue inherited as an autosomal dominant trait. The disorder imparts significant morbidity and mortality. The etiology of the disorder remains elusive. A recent study localized the gene for Marfan syndrome on chromosome 15. We present data showing that marker D15S48 is genetically linked to Marfan syndrome. Pairwise linkage analysis gave a maximum lod (logarithm of odds) score of Z = 11.78 at theta = 0.02. Furthermore our data suggest that the Marfan syndrome locus is possibly flanked on either side by D15S48 and D15S49.
Commitment to the CD4 Lineage Mediated by Extracellular Signal-Related Kinase Mitogen-Activated Protein Kinase and Lck Signaling (1999)

The development of T cells results in a concordance between the specificity of the TCR for MHC class I and class II molecules and the expression of CD8 and CD4 coreceptors. Based on analogy to simple metazoan models of organ development and lineage commitment, we sought to determine whether extracellular signal-related kinase (Erk) mitogen-activated protein (MAP) kinase pathway signaling acts as an inductive signal for the CD4 lineage. Here, we show that, by altering the intracellular signaling involving the Erk/MAP kinase pathway, T cells with specificity for MHC class I can be diverted to express CD4, and, conversely, T cells with specificity for MHC class II can be diverted to express CD8. Furthermore, we find that activation of the src-family tyrosine kinase, p56lck is an upstream mediator of lineage commitment. These results suggest a simple mechanism for lineage commitment in T cell development.
Digital Microfluidic Platform to Maximize Diagnostic Tests with Low Sample Volumes from Newborns and Pediatric Patients (2020)

"Children are not tiny adults" is an adage commonly used in pediatrics to emphasize the fact that children often have different physiological responses to sickness and trauma compared to adults. However, despite widespread acceptance of this concept, diagnostic blood testing is an excellent example of clinical care that is not yet customized to the needs of children, especially newborns. Cumulative blood loss resulting from clinical testing does not typically impact critically ill adult patients, but can quickly escalate in children, leading to iatrogenic anemia and related comorbidities. Moreover, the tests prioritized for rapid, near-patient testing in adults are not always the most clinically relevant tests for children or newborns. This report describes the development of a digital microfluidic testing platform and associated clinical assays purposely curated to address current shortcomings in pediatric laboratory testing by using microliter volumes (<50 µL) of samples. The automated platform consists of a small instrument and single-use cartridges, which contain all reagents necessary to prepare the sample and perform the assay. Electrowetting technology is used to precisely manipulate nanoliter-sized droplets of samples and reagents inside the cartridge. To date, we have automated three disparate types of assays (biochemical assays, immunoassays, and molecular assays) on the platform and have developed over two dozen unique tests, each with important clinical application to newborns and pediatric patients. Cell lysis, plasma preparation, magnetic bead washing, thermocycling, incubation, and many other essential functions were all performed on the cartridge without any user intervention. The resulting assays demonstrate performance comparable to standard clinical laboratory assays and are economical due to the reduced hands-on effort required for each assay and lower overall reagent consumption. These capabilities allow a wide range of assays to be run simultaneously on the same cartridge using significantly reduced sample volumes with results in minutes.
Two human homeobox genes, c1 and c8: structure analysis and expression in embryonic development. (1987)

Two human cDNA clones (HHO.c1.95 and HHO.c8.5111) containing a homeobox region have been characterized, and the respective genomic regions have been partially analyzed. Expression of the corresponding genes, termed c1 and c8, was evaluated in different organs and body parts during human embryonic/fetal development. HHO.c1.95 apparently encodes a 217-amino acid protein containing a class I homeodomain that shares 60 out of 61 amino acid residues with the Antennapedia homeodomain of Drosophila melanogaster. HHO.c8.5111 encodes a 153-amino acid protein containing a homeodomain identical to that of the frog AC1 gene. Clones HHO.c1 and HHO.c8 detect by blot-hydridization one and two specific polyadenylylated transcripts, respectively. These are differentially expressed in spinal cord, backbone rudiments, limb buds (or limbs), heart, and skin of human embryos and early fetuses in the 5- to 9-week postfertilization period, thus suggesting that the c1 and c8 genes play a key role in a variety of developmental processes. Together, the results of the embryonic/fetal expression of c1 and c8 and those of two previously analyzed genes (c10 and c13) indicate a coherent pattern of expression of these genes in early human ontogeny.
Prognostic value of intraoperative pleural lavage cytology for lung cancer without carcinomatous pleuritis: importance in patients with early stage disease during long-term follow-up☆ (2008)

Based on the present analysis of long-term follow-up after operation, PLC may also be an independent prognostic factor. In particular, the PLC status of patients with stage I disease or adenocarcinoma type has an important impact on survival. PLC-positive findings may be a high risk for postoperative pleural recurrence. For PLC-positive patients with stage I disease, careful serial follow-up for more than 5 years is required while paying attention to late pleural recurrence.
Minimal luminal diameter versus percent diameter narrowing for assessing coronary artery disease (1989)

_ oDs or CiARJi):IOiVii\&#39;SCiULAR DiAGNos1s/ Luminal Diameter Percent Diameter Assessing Coronary Artery Disease Jonathan Tobis, MD - David Oakes, MD - David Sato, MD 5 Orhan Nalcioglu, PhD - Warren D. Johnston, MD - John Mallery, MD S -Jackie See, MD ° Lian Qu, MS 0 Tim Reese, BS S L I Jim Paynter, RCPT - Steve Montelli, CRT - Walter L. Henry, MD‘ From the Division of Cardiology and Department of Radiological Sciences, University of California, Irvine, California. UPDATE: Stenotic coronary arterial segments of 27 patients were measured by the percent diameter narrowing and minimal luminal diameter methods. The measurements were analyzed for correlation with changes in global ejection fraction and segmental wall motion during atrial pacing. Ten patients without coronary artery disease served as a control group. Minimal luminal diameter correlated more closely with impairment of myocardial contractility than did percent diameter narrowing. Therefore, we conclude that the former is a better method for assessing the seiverityof coronary y is artery disease. ; v oronaryarteriography is indispen- sable ‘for the clinical assessment of patients svvith coronary artery disease. Since its devel- goprnent in the early 1960s, coronary arteri- S sography has been relied on for the accurate delineation of coronary anatomy and for allowing inferencesto be drawn regarding , the hemodynamic effects of coronary arte- D rial stenoses.1?2Traditionally, the severity of coronaryartery diseasehas been graded by measuring the percent diameter narrowing between, the stenotic segment and a proxi- mal segment with normal -appearance.“ Such measurements can be made by visual inspection or-computer-assisted quantitative angiographic techniques.5 a t Although percent diameternarrowing is useful for distinguishing patients with nor- if SCARDIOLOGY BOARD REVIEW ._.._.»..i-u-ernr-:(\(b(&#39;)qBq’(})a:)
Intrinsic Differences in L-Selectin Expression Levels Affect T and B Lymphocyte Subset-Specific Recirculation Pathways (1998)

Lymphocyte migration into lymphoid organs is regulated by tissue-specific adhesion molecules such as L-selectin and the alpha4beta7 integrin. Whether L-selectin also regulates lymphocyte subset-specific migration into specific lymphoid tissues was examined in this study by comparing the migration of CD4+ T cells, CD8+ T cells, and B cells from L-selectin-deficient and wild-type mice. T cells were the predominant lymphocyte subset entering PLN, MLN, Peyer's patches, and spleen during short term (1-h) migration assays. However, both B cell and CD4+ and CD8+ T cell entries into PLN, MLN, and Peyer's patches were dramatically impaired (73-98%) by loss of L-selectin. Lymphocyte expression of alpha4beta7 integrin did not compensate for the loss of L-selectin, since both B and T cells predominantly migrated into the spleen in the absence of L-selectin. The more efficient migration of T cells into peripheral lymphoid tissues relative to that of B cells was partly explained by the finding that T cells expressed L-selectin at 50 to 100% higher levels than B cells. In addition, a 50% reduction in L-selectin expression by lymphocytes from hemizygous L-selectin(+/-) mice resulted in a 50 to 70% decrease in short term lymphocyte migration into peripheral lymphoid tissues relative to that of wild-type lymphocytes. Thus, the differential migration of T and B lymphocyte subsets to lymphoid tissues is regulated in part by subset-specific differences in L-selectin expression levels.
Haplotype analysis and identification of genes for a complex trait: examples from schizophrenia (2004)

For more than a decade there has been intensive research into the genetic etiology of schizophrenia, yet it is only recently that the first findings of promising genes associating with the disorder have been reported. Linkage analyses in families collected from different populations have provided relatively well defined genomic loci. These have been typically followed by fine mapping studies using single nucleotide polymorphisms (SNPs). A number of analysis programs have been produced to test SNPs and their haplotypes for association. Typically association has been established to specific haplotypes representing an allelic variant of the corresponding gene. The inherent problem of multiple testing in the analysis of haplotypes needs to be addressed fully, to determine if any of these recent findings can be considered as confirmed susceptibility genes for schizophrenia. However, informative haplotypes have provided a way to define allelic variants of genes associated with schizophrenia in numerous study samples, and are a useful tool in characterizing the extent of allelic diversity of putative schizophrenia susceptibility genes within different populations.
Real-time 3D-based Virtual Eye Contact for Video Communication (2019)

Das Problem des fehlenden Augenkontaktes vermindert den Eindruck einer natürlichen Kommunikationssituation bei Videokonferenzen. Während eine Person auf den Bildschirm blickt, wird sie von Kameras aufgenommen, die sich normalerweise direkt daneben befinden. Mit dem Aufkommen von massiv paralleler Computer Hardware und ganz speziell den sehr leistungsstarken Spielegrafikkarten ist es möglich geworden, viele Eingabeansichten für eine Echtzeit 3D Rekonstruktion zu verarbeiten. Eine größere Anzahl von Eingabeansichten mildert Verdeckungsprobleme ab und führt zu vollständigeren 3D Daten. In dieser Arbeit werden neue Algorithmen vorgeschlagen, welche eine hochqualitative Echtzeit 3D Rekonstruktion, die kontinuierliche Anpassung der photometrischen Kameraparameter und die benutzerunabhängige Schätzung der Augenkontaktkameras ermöglichen. Die Echtzeit 3D Analyse besteht aus zwei komplementären Ansätzen. Einerseits gibt es einen Algorithmus, der auf der Verarbeitung geometrischer Formen basiert und auf der anderen Seite steht eine patchbasierte Technik, die 3D Hypothesen durch das Vergleichen von Bildtexturen evaluiert. Zur Vorbereitung für die Bildsynthese ist es notwendig, Texturen von verschiedenen Ansichten anzugleichen. Hierfür wird die Anwendung eines neuen Algorithmus zur kontinuierlichen photometrischen Justierung der Kameraparameter vorgeschlagen. Die photometrische Anpassung wird iterativ, im Wechsel mit einer 3D Registrierung der entsprechenden Ansichten, ausgeführt. So ist die Qualität der photometrischen Parameter direkt mit jener der Ergebnisse der 3D Analyse verbunden und vice versa. Eine weitere wichtige Voraussetzung für eine korrekte Synthese der Augenkontaktansicht ist die Schätzung einer passenden virtuellen Augenkontaktkamera. Hierfür wird die Augenkontaktkamera kontinuierlich an die Augenposition der Benutzer angeglichen. Auf diese Weise wird eine virtuelle Kommunikationsumgebung geschaffen, die eine natürlichere Kommunikation ermöglicht.
Urea-Hydroxyapatite Nanohybrids for Slow Release of Nitrogen (2017)

While slow release of chemicals has been widely applied for drug delivery, little work has been done on using this general nanotechnology-based principle for delivering nutrients to crops. In developing countries, the cost of fertilizers can be significant and is often the limiting factor for food supply. Thus, it is important to develop technologies that minimize the cost of fertilizers through efficient and targeted delivery. Urea is a rich source of nitrogen and therefore a commonly used fertilizer. We focus our work on the synthesis of environmentally benign nanoparticles carrying urea as the crop nutrient that can be released in a programmed manner for use as a nanofertilizer. In this study, the high solubility of urea molecules has been reduced by incorporating it into a matrix of hydroxyapatite nanoparticles. Hydroxyapatite nanoparticles have been selected due to their excellent biocompatibility while acting as a rich phosphorus source. In addition, the high surface area offered by nanoparticles allows binding of a large amount of urea molecules. The method reported here is simple and scalable, allowing the synthesis of a urea-modified hydroxyapatite nanohybrid as fertilizer having a ratio of urea to hydroxyapatite of 6:1 by weight. Specifically, a nanohybrid suspension was synthesized by in situ coating of hydroxyapatite with urea at the nanoscale. In addition to the stabilization imparted due to the high surface area to volume ratio of the nanoparticles, supplementary stabilization leading to high loading of urea was provided by flash drying the suspension to obtain a solid nanohybrid. This nanohybrid with a nitrogen weight of 40% provides a platform for its slow release. Its potential application in agriculture to maintain yield and reduce the amount of urea used is demonstrated.