gebhart/patrepeval huggingface dataset:
Use of magnetic resonance imaging in detecting subclinical synovitis in rheumatoid arthritis and correlation of imaging findings with interleukin‐18 levels (2014)

MRI is more sensitive in detecting erosions compared with X-rays, and is superior in its ability to detect subclinical inflammation in RA patients. Despite being in clinical remission, a large majority of patients had imaging-detected synovitis and bone marrow edema. Our study highlights the usefulness of MRI for the accurate evaluation of disease activity. In the utility of MRI, it may be important to assess bilateral hands and wrists, instead of limiting to the dominant side.
Improved Runnability and Drying Capacity through New Technology (2007)

既設抄紙機を改造する場合の目的は主として生産量の向上又は品質改善にあり，多くはウェットエンドのみ改造し，ドライエンドの改造は行わない。これによって今度はドライヤが生産又は品質向上のボトルネックになることがある。ここでは走行性と乾燥効率向上のための新しい方式について紹介する。初めに新しい走行改善機器について紹介し，その効果と紙の品質についてパイロットテスト機と実機の運転結果を記載する。次に紙及び板紙に適用する新しいインピンジメントドライヤコンセプトを紹介する。高速抄紙機に於いては乾燥工程の初期に於いて走行性の問題を起こすことがあり，その高いドローによって紙の品質低下を引き起してしまうことがある。ドローを低くするには通常，効果的なブローボックスの設置によって行われるが，シリンダドライヤ入口での紙のドライネスを高くする方法もある。つまり温度の低い紙が温度の高いシリンダドライヤ表面に接触する前に，インピンジメントドライヤを適用することで行われる。新しく開発されたインピンジメントドライヤはプレス直後に設置されシリンダ入口でのドライネスを向上させている。従って紙のドライネス，温度が上昇することで紙の強度は向上し走行性は従来よりも良好となる。
<title>Dynamic response tuning of composite beams by embedded shape memory alloy actuators</title> (2000)

The thermomechanical performance of a shape memory alloy hybrid composite beam specimen is demonstrated and used in a preliminary validation study of a recently developed constitutive model and finite element formulation for analysis of such structures. A brief description of the thermoelastic formulation is given. A material system consisting of a glass/epoxy matrix with embedded Nitinol actuators was chosen for this study. Results from Nitinol material characterization testing, beam specimen fabrication processes, and base acceleration testing for measuring the dynamic response performance in presented. Selected results from the dynamic test are shown, interpreted, and compared with predictions form the FE model. Elimination of a thermal post-buckling deflection by the activated SMA was observed. The fundamental natural frequency is shown to increase by a facto of 5.3 and the RMS displacement response is attenuated by a factor 6.4. Preliminary comparisons between predicted and measured performance is good. Discrepancies are attributable to insufficient knowledge of the matrix material properties at elevated temperature.
Low-complexity inter-sequence error concealment based on scale-invariant feature transform (2009)

Inter-sequence error concealment defines a novel class of concealment techniques which utilize two or more representations of a particular video sequence for image reconstruction. An image-based approach introduced recently provides superior reconstruction quality of concealed image parts and outperforms well-known intra methods by up to 15 dB PSNR <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Y</sub> . However, computational complexity is high due to a numerical solution of the image registration problem. In this paper, we propose a feature-based technique for image registration which is included in the concept of inter-sequence error concealment. Based on the determination of scale-invariant features, the processing time is reduced on average by a factor of up to 28. At the same time, the loss in terms of objective image quality compared to the image-based approach is less than 1 dB PSNR <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Y</sub> .
A Dynamic Grouping Strategy for Beyond Diagonal Reconfigurable Intelligent Surfaces With Hybrid Transmitting and Reflecting Mode (2023)

Beyond diagonal reconfigurable intelligent surface (BD-RIS) is a novel branch of RIS which breaks through the limitation of conventional RIS with diagonal scattering matrices. However, the existing research focuses on BD-RIS with fixed architectures regardless of channel state information (CSI), which limit the achievable performance of BD-RIS. To solve this issue, in this paper, we propose a novel dynamically group-connected BD-RIS based on a dynamic grouping strategy. Specifically, RIS antennas are dynamically divided into several subsets adapting to the CSI, yielding a permuted block-diagonal scattering matrix. To verify the effectiveness of the proposed dynamically group-connected BD-RIS, we propose an efficient algorithm to optimize the BD-RIS with dynamic grouping for a BD-RIS-assisted multi-user multiple-input single-output system. Simulation results show that the proposed dynamically group-connected architecture outperforms fixed group-connected architectures.
Memory-efficient semi-quasi-arithmetic coding (2005)

A highly efficient, lookup table-based, renormalization method is proposed, which can be used by any binary arithmetic coder with the follow-on procedure. It replaces the time-consuming branching operations in the renormalization process with table lookups and some simple bit-wise operations. We show that the proposed method is much faster than the one used by the M coder in the CABAC entropy coding scheme of the H.264 video coding standard. Our method requires much less memory than the previously known, table-based quasi-coder.
A Rapid-Injection Nuclear Magnetic Resonance Study of the Butyllithium-Initiated Polymerization of Styrene (1995)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA Rapid-Injection Nuclear Magnetic Resonance Study of the Butyllithium-Initiated Polymerization of StyreneCraig A. Ogle, Harry C. Johnson IV, Xiao Li Wang, Frederick H. Strickler, Daniel Bucca, and Bernard III GordonCite this: Macromolecules 1995, 28, 15, 5184–5191Publication Date (Print):July 1, 1995Publication History Published online1 May 2002Published inissue 1 July 1995https://pubs.acs.org/doi/10.1021/ma00119a004https://doi.org/10.1021/ma00119a004research-articleACS PublicationsRequest reuse permissionsArticle Views170Altmetric-Citations13LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Compact Two-Layer Rotman Lens-Fed Microstrip Antenna Array at 24 GHz (2010)

This paper presents a new design to realize a compact Rotman lens-fed antenna array. The lens-fed antenna has the form of two layers, which is a new approach to reducing the size of the Rotman lens. The approach is demonstrated at 24 GHz aiming for an automotive sensing radar. The lens consists of a top metal layer, a dielectric, a common ground, a dielectric, and a bottom metal layer, in sequential order. The layout of the lens body is placed on the bottom layer and the antennas are placed on the top layer. Both of them are electrically connected through slot transitions. This two-layer structure reduces not only the total size of the lens, but also the loss of the delay lines because the lines can be designed to be as short and straight as possible. The two-layer Rotman lens-fed antenna array is measured in terms of scattering parameters and beam patterns. From the scattering parameters, the power efficiencies of the beam port 1, 2, and 3 at 24 GHz are obtained as 32.3%, 48.5%, and 50.8%, respectively. The measured beam patterns show that the beam directions are -28.1°, -14.9°, 0°, 15.5°, and 28.6° and the beamwidths are 13.4°, 13.2°, 12.8°, 13.5°, and 13.0°. The measurements confirm that the compact two-layer Rotman lens has been successfully demonstrated.
Table S5 from Identification of Recurrent <i>FGFR3–TACC3</i> Fusion Oncogenes from Lung Adenocarcinoma (2023)

&lt;p&gt;Table S5. Variants, copy number alterations and rearrangements identified in 24 samples by targeted next generation sequencing (NGS). In the copy number alterations column samples were classified based on gene copy number in two: (A) = amplified (&gt; 2 copies of the gene) and (L) = Low (&lt; 2 copies of the gene). Sample 2 is reported in the main text as CG-42.&lt;/p&gt;
Colloidal crystal order and structure revealed by tabletop extreme ultraviolet scattering and coherent diffractive imaging (2018)

Colloidal crystals with specific electronic, optical, magnetic, vibrational properties, can be rationally designed by controlling fundamental parameters such as chemical composition, scale, periodicity and lattice symmetry. In particular, silica nanospheres -which assemble to form colloidal crystals- are ideal for this purpose, because of the ability to infiltrate their templates with semiconductors or metals. However characterization of these crystals is often limited to techniques such as grazing incidence small-angle scattering that provide only global structural information and also often require synchrotron sources. Here we demonstrate small-angle Bragg scattering from nanostructured materials using a tabletop-scale setup based on high-harmonic generation, to reveal important information about the local order of nanosphere grains, separated by grain boundaries and discontinuities. We also apply full-field quantitative ptychographic imaging to visualize the extended structure of a silica close-packed nanosphere multilayer, with thickness information encoded in the phase. These combined techniques allow us to simultaneously characterize the silica nanospheres size, their symmetry and distribution within single colloidal crystal grains, the local arrangement of nearest-neighbor grains, as well as to quantitatively determine the number of layers within the sample. Key to this advance is the good match between the high harmonic wavelength used (13.5nm) and the high transmission, high scattering efficiency, and low sample damage of the silica colloidal crystal at this wavelength. As a result, the relevant distances in the sample - namely, the interparticle distance (≈124nm) and the colloidal grains local arrangement (≈1μm) - can be investigated with Bragg coherent EUV scatterometry and ptychographic imaging within the same experiment simply by tuning the EUV spot size at the sample plane (5μm and 15μm respectively). In addition, the high spatial coherence of high harmonics light, combined with advances in imaging techniques, makes it possible to image near-periodic structures quantitatively and nondestructively, and enables the observation of the extended order of quasi-periodic colloidal crystals, with a spatial resolution better than 20nm. In the future, by harnessing the high time-resolution of tabletop high harmonics, this technique can be extended to dynamically image the three-dimensional electronic, magnetic, and transport properties of functional nanosystems.
In vivo gene immunotherapy for cancer (2022)

Cancer is becoming increasingly understood not only as a disease of pathological cells but also as one of immune hypofunction. The heterogenous and patient-specific nature of cancer further underscores the need for personalized cellular therapies, which are currently produced ex vivo. Gene-modulating approaches, such as therapeutic RNAs and improved viral vectors, now bring us closer toward strategies for mitigating disease, particularly for diseases that benefit from altering gene or transgene expression profiles in pathological or therapeutic immune cells. An advancing toolbox of technologies and trends toward simplifying personalized therapies foreshadow opportunities for direct, in vivo precision medicine against cancer.
Response to Comment on “Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells” (2018)

Evers et al. employed CRISPR/Cas9 technology to generate B cell populations missing the BCR as an additional (negative) control, to investigate the contribution of the BCR in anti-CD20–mediated complement-dependent cytotoxicity (CDC) that we proposed ([1][1]). We agree with the notion that loss of
<title>Equal fan-out optical interconnects using DuPont photopolymer films</title> (1997)

In this paper, concerning with the practical applications of substrate guided wave optical interconnects, one-to-many surface-normal fanout devices with equalized fanout energy distribution are addressed and then demonstrated. DuPont photopolymer film HRF-600X001-20 is used in our experiment. The optimum recording beam intensity is investigated for obtaining large dynamic region of diffraction efficiency versus exposure dosage. Based on the experimental diffraction efficiency curve, 1-to-5 and 1-to-9 surface- normal fanout devices are fabricated operating at a wavelength of 850 nm. Output energy fluctuations of +/- 4 percent and +/- 10 percent are obtained for the two devices.
Inverted spin valves with irmn biasing layer (2005)

Summary form only given. The complete presentation was not made available for publication as part of the conference proceedings.
Rough Seas and Statistical Deconvolution (2001)

A-22 ROUGH SEAS AND STATISTICAL DECONVOLUTION E. KRAGH and R. LAWS 1 Schlumberger Cambridge Research High Cross Madingley Road Cambridge CB3 OEL UK Summary: The rough sea ghost response varies along the streamer from shot to shot and with time along the seismic trace. In this paper we examine the application of statistical deconvolution to reduce the rough sea error. Although this conventional method incorrectly assumes wavelet stationarity a partial correction can be achieved provided some modification of the standard application is carried out; the design window should be no longer than 1 s and the application window should lie
Anaerobic Digestion of Food Waste with Unconventional Co-Substrates for Stable Biogas Production at High Organic Loading Rates (2019)

Anaerobic digestion (AD) is widely considered a more sustainable food waste management method than conventional technologies, such as landfilling and incineration. To improve economic performance while maintaining AD system stability at commercial scale, food waste is often co-digested with animal manure, but there is increasing interest in food waste-only digestion. We investigated the stability of anaerobic digestion with mixed cafeteria food waste (CFW) as the main substrate, combined in a semi-continuous mode with acid whey, waste bread, waste energy drinks, and soiled paper napkins as co-substrates. During digestion of CFW without any co-substrates, the maximum specific methane yield (SMY) was 363 mL gVS−1d−1 at organic loading rate (OLR) of 2.8 gVSL−1d−1, and reactor failure occurred at OLR of 3.5 gVSL−1d−1. Co-substrates of acid whey, waste energy drinks, and waste bread resulted in maximum SMY of 455, 453, and 479 mL gVS−1d−1, respectively, and it was possible to achieve stable digestion at OLR as high as 4.4 gVSL−1d−1. These results offer a potential approach to high organic loading rate digestion of food waste without using animal manure. Process optimization for the use of unconventional co-substrates may help enable deployment of anaerobic digesters for food waste management in urban and institutional applications and enable increased diversion of food waste from landfills in heavily populated regions.
Articulatory information and Multiview Features for Large Vocabulary\n Continuous Speech Recognition (2018)

This paper explores the use of multi-view features and their discriminative\ntransforms in a convolutional deep neural network (CNN) architecture for a\ncontinuous large vocabulary speech recognition task. Mel-filterbank energies\nand perceptually motivated forced damped oscillator coefficient (DOC) features\nare used after feature-space maximum-likelihood linear regression (fMLLR)\ntransforms, which are combined and fed as a multi-view feature to a single CNN\nacoustic model. Use of multi-view feature representation demonstrated\nsignificant reduction in word error rates (WERs) compared to the use of\nindividual features by themselves. In addition, when articulatory information\nwas used as an additional input to a fused deep neural network (DNN) and CNN\nacoustic model, it was found to demonstrate further reduction in WER for the\nSwitchboard subset and the CallHome subset (containing partly non-native\naccented speech) of the NIST 2000 conversational telephone speech test set,\nreducing the error rate by 12% relative to the baseline in both cases. This\nwork shows that multi-view features in association with articulatory\ninformation can improve speech recognition robustness to spontaneous and\nnon-native speech.\n
Kerr-Lens Mode-Locked Middle IR Polycrystalline Cr:ZnS Laser with a Repetition Rate 1.2 GHz (2016)

We report flexible design of femtosecond middle-IR lasers with a broad range of repetition rates 0.08–1.2 GHz. The lasers emit few-cycle pulses with 4–16.4 THz bandwidth, 0.1– 21 nJ energy at 2.4 µm wavelength.
Comparative properties of glycogen phosphorylase. VIII. Phosphorylase from dogfish skeletal muscle. Purification and a comparison of its physical properties to those of rabbit muscle phosphorylase (1971)

Large amounts of glycogen phosphorylases b and a (EC 2.4.1.1) have been purified from skeletal muscles of the Pacific dogfish (Squalus sucklii) to a state of homogeneity as judged by the criteria of ultracentrifuge analysis and poly-acrylamide gel electrophoresis. An investigation of the molecular properties showed many similarities and certain distinct differences when compared to those of rabbit skeletal muscle phosphorylases b and a. Specific activities of dogfish phosphorylase b (62 units/mg with AMP, &lt;1 without AMP) and a (62 and 48 units per mg with and without AMP) were comparable to those of the rabbit enzymes (88 and &lt;1 units per mg for b, and 80 and 54 for a when measured with and without AMP, respectively). Other closely similar properties for dogfish and rabbit phosphorylase b, respectively, include the absorbancy indices A<sup>1%</sup> <sub>280</sub> (12.9 vs. 13.1), 260/280 nm ratios (0.56 vs. 0.53), the apparent specific volumes (0.746 vs. 0.746 ± 0.002), sedimentation coefficients (8.9 S vs. 8.8 S), subunit size, and molecular weights (100,000 ± 1000 and 200,000 ± 2000 for both enzymes). Dogfish and rabbit phosphorylase b both incorporated one molecule of phosphate per subunit in the b into a conversion, and dogfish phosphorylases b and a were as good substrates for rabbit muscle phosphorylase kinase and phosphatase, respectively, as were the rabbit muscle phosphorylases themselves. Each enzyme contained one molecule of pyridoxal 5'-phosphate per subunit and interactions between this cofactor and the proteins were very similar. Dogfish phosphorylase a was only 20-25% associated from dimer to tetramer under conditions where rabbit phosphorylase a was completely in a tetrameric form. Addition of NaCl to 0.5 m promoted further tetramerization (to ca. 40%), but had no effect on the subunit interactions of rabbit phosphorylase a, although dissociation of the latter toward dimer occurred above 1.5 M NaCl. Likewise, 2 mM AMP had no effect on the s<sub>20,w</sub> or molecular weights of dogfish phosphorylase b, whereas rabbit phosphorylase b was 75-80% associated to tetramer at 10° under these conditions. In contrast to the rabbit enzymes, neither a nor b (in the presence of Mg<sup>2+</sup> and AMP) crystallized at 0°, suggesting an inverse correlation between solubility at low temperature and tetramerization. The K<sub>m</sub> for glycogen as primer also differed markedly for dogfish and rabbit phosphorylase b (0.12 and 0.018%, respectively). The subunit molecular weight obtained for phosphorylases from both species is 8% higher than had previously been reported for the rabbit muscle enzyme. The reasons for a revision in both the size of the polypeptide chain and the nature of the interactions between subunits is discussed, together with possible implications of the differences observed between the rabbit and dogfish enzymes.
Preclinical efficacy of the dual sigma receptor antagonist dopamine uptake inhibitor, CM699, as a medication for stimulant abuse (803.3) (2014)

Sigma receptor (σR) antagonists block many effects of stimulants, but not reinforcing effects assessed with self‐administration (SA). Yet, a recent study suggests that σR antagonism with dopamine transporter (DAT) inhibition selectively blocks stimulant SA. A compound with potential for dual σR‐DAT inhibition was synthesized by treating 1‐methyl‐2‐benzimidazolinone with 1,4‐dibromobutane in the presence of K 2 CO 3 in dimethylformamide (DMF), yielding a compound that was then coupled with 3 H ‐spiro[isobenzofuran‐1,4'‐piperidine] in the presence of K 2 CO 3 in DMF. The resulting compound, CM699, had affinities of 14, 2.30 and 318 nM at σ 1 Rs, σ 2 Rs and DAT, respectively. Antagonism at σ 1 Rs was confirmed by Western blots of σ 1 R‐EYFP bound to the ER chaperone, Binding immunoglobulin Protein (BiP). CM699 had no effect whereas the agonist, (+)‐pentazocine decreased BiP association. CM699 (5.0 mg/kg, iv) in rats produced a Cmax of 1.84 µg/mL in plasma, 5 min after injection which declined exponentially (overall T ½ = 4.4 hr). CM699 produced dose‐dependent insurmountable and selective antagonism of cocaine SA in rats (ED 50 = 3.99 mg/kg, ip) and blunted effects of cocaine on dopamine (DA) levels in the rat nucleus accumbens, indicating minimal abuse liability. The results provide preclinical proof of concept for dual σR/DAT inhibition as a novel approach for the development of medications to treat stimulant abuse. Grant Funding Source : NIH Intramural Research Program
Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development (2021)

Lodge et al. screened 28 patients with pituitary stalk interruption syndrome (PSIS) for mutations in the FAT/DCHS (FAT atypical cadherin/ Dachsous cadherin-related) family of protocadherins. FAT2 and DCHS2 putative damaging variants were found in 6/28 patients with ectopic posterior pituitary (EPP) and PSIS. The affected patients had either multiple pituitary hormone deficiency (MPHD) or isolated growth hormone deficiency.
A Dual-Band Rectifying Antenna Design for RF Energy Harvesting (2020)

A novel dual-band rectifying antenna (also termed rectenna) is designed to harvest ambient energy at WIFI frequencies. The proposed rectenna consists of a Coplanar Waveguide (CPW) Folded-Slot (FS) antenna, a two-stages matching network, a half-wave rectifier circuit, and a resistive load. The CPW FS antenna is designed and demonstrated to resonate at both 2.4 and 5.2 GHz at a compact size of 55mm×30mm with a measured Return Loss (RL) higher than 20dB at each resonance, respectively. Harmonic Balance (HB) simulation is then performed to sweep input power levels and load resistance values to achieve the highest RF-DC conversion efficiency and corresponding output DC voltages. Expected RF-DC conversion efficiency and output DC voltage level at first resonance are 63.38% and 1.4V at an input power of 13 dBm and a load of 150 Ω. At the secondary resonance, the maximum conversion efficiency and output voltage can reach up to 65.4% and 1.53V at input power of 13 dBm and load of 150 Ω.