gebhart/patrepeval huggingface dataset:
Neuroinflammation contributes to hypokinesia in rats with hepatic encephalopathy: Ibuprofen restores its motor activity (2008)

Patients with hepatic encephalopathy show altered motor function, psychomotor slowing, and hypokinesia, which are reproduced in rats with portacaval shunts (PCS). Increased extracellular glutamate in substantia nigra pars reticulata (SNr) is responsible for hypokinesia in PCS rats. The mechanisms by which liver failure leads to increased extracellular glutamate in SNr remain unclear. Inflammation seems to act synergistically with hyperammonemia to induce neurological alterations in hepatic encephalopathy. It is therefore possible that inflammation-associated alterations may contribute to motor alterations in hepatic encephalopathy. The aim of this work was to assess whether treatment with an antiinflammatory, ibuprofen, is able to normalize extracellular glutamate in SNr and/or to improve hypokinesia in PCS rats. The amounts of the glutamate transporters GLT-1 and EAAC-1 are reduced by 26% and 32%, respectively, in SNr of PCS rats. This reduction is associated with a tenfold increase in extracellular glutamate in SNr and a reduction in motor activity. Chronic treatment with 30 mg/kg ibuprofen completely normalizes the amount of GLT-1 and EAAC-1 and significantly reduces (by 53%) extracellular glutamate in SNr of PCS rats. Moreover, ibuprofen, at 15 or 30 (but not at 5) mg/kg/day, completely eliminates hypokinesia, restoring normal motor activity. This supports the idea that inflammation is a main contributor to the induction of hypokinesia in hepatic encephalopathy. Moreover, these data point to the possible therapeutic utility of decreasing inflammation, by safe procedures, in the treatment of the motor deficits in patients with hepatic encephalopathy.
On-line personalization of a touch screen based keyboard (2003)

The user expectations for usability and personalization along with decreasing size of handheld devices challenge traditional keypad layout design. We have developed a method for on-line adaptation of a touch pad keyboard layout. The method starts from an original layout and monitors the usage of the keyboard by recording and analyzing the keystrokes. An on-line learning algorithm subtly moves the keys according to the spatial distribution of keystrokes. In consequence, the keyboard matches better to the users physical extensions and grasp of the device, and makes the physical trajectories during typing more comfortable. We present two implementations that apply different vector quantization algorithms to produce an adaptive keyboard with visual on-line feedback. Both qualitative and quantitative results show that the changes in the keyboard are consistent, and related to the user's handedness and hand extensions. The testees found the on-line personalization positive. The method can either be applied for on-line personalization of keyboards or for ergonomics research
Cross- and Iso- oriented surrounds modulate the contrast response function: The effect of surround contrast (2003)

The detectability and appearance of visual targets can be modulated by surround stimuli. In this study we asked how cross- and iso-oriented surrounds modulate contrast detection and discrimination in foveal vision. We systematically measured the Threshold-versus-Contrast (TvC) functions over a wide range of pedestal and surround contrasts. Our results show that cross-oriented surrounds lower the contrast threshold over the entire range of pedestal and surround contrasts, but iso-surround modulation of the TvC function is dependent on the relative contrast, being facilitative when the surround/pedestal contrast ratio Csur/Cped < 1 and suppressive when Csur/Cped > 1. Data fitting indicates that cross-surround modulation (facilitation) is mainly due to improved gain, except at very low and high surround contrasts. Iso-surround modulation on the other hand is more complicated, probably reflecting more than one surround process as determined by the relative contrast.
DRED‐MP: Queue management with multiple levels of drop precedence (2004)

Abstract There is current interest in differentiated service architectures where packets with different priorities can share the same queue. In the case of congestion, packets marked with higher drop probability are preferentially dropped in order to make buffer room for packets marked with lower drop probability. Active queue management (AQM) based on randomized packet dropping has become a key component of this packet forwarding model. This paper extends our previously developed AQM algorithm called DRED with multiple packet drop precedence to allow for priority treatment of traffic in a network. The main advantage of using the DRED algorithm is the lower parameter configuration complexity it offers and the ease of configuration for a wide range of network conditions. Copyright © 2004 John Wiley &amp; Sons, Ltd.
Derivatives of 5α-androstan-3α- and 3β-ol with acrylate side chain (1990)

Hydroxy derivatives I, II, III, XVII and XX were oxidized to give the respective aldehydes IV, V, VI, XVIII and XXI which were further converted by Wittig-Horner reaction into unsaturated methyl and ethyl esters. Removal of the acetal protecting group in position 3 afforded methylesters X, XXIV and XXXVI and ethyl esters XIV, XXV and XXXVII . Compounds XXIV, XXV, XXXVI and XXXVII were converted into the corresponding hemisuccinates XXVIII, XXIX, XL and XLI and β-D-glucosides XXXII, XXXIII, XLIV and XLV .
Localization of myosin-V in the centrosome (1998)

The perinuclear localization of myosin-V was investigated in a variety of cultured mammalian cells and in primary cultures of rat hippocampus. In all cells investigated, myosin-V immunoreactivity was associated with the centrosome. In interphase cells, myosin-V was found in pericentriolar material, and in both mother and daughter centrioles. These results were obtained by using two different fixation protocols with three different affinity-purified antibodies that recognized a single band in Western blots. During cell division, myosin-V staining was intense throughout the cytoplasm and was concentrated in a trail between migrating centrioles and in the mitotic spindle poles and spindle fibers. The centrosome targeting site was determined to reside within the globular tail domain, because centrosome association also was observed in living cells transfected with DNA encoding the tail domain fused with a green fluorescent protein tag, but not in cells transfected with the vector encoding green fluorescent protein by itself.
Robust Estimation of Product Amount on Store Shelves from a Surveillance Camera for Improving On-Shelf Availability (2018)

This paper proposes a method to robustly estimate product amount on store shelves from a surveillance camera for improving on-shelf availability. We focus on changes of products on the shelves such as “product taken (decrease)” and “product replenished/returned (increase)”, and compute product amount by accurately accumulating them. The proposed method first detects change regions of products on the shelves in an image using background subtraction followed by moving object removal. The detected change regions are then classified into several classes representing the actual changes on the shelves such as “product taken” by using convolutional neural networks. Finally, the changes of products on the shelves are accumulated using classification results, and product amount on the shelves visible in the image is computed as on-shelf availability. Experimental results using two videos captured in a real store show that our method achieves success rate of 89.6% for on-shelf availability when an error margin is within one product. With high accuracy, store clerks can keep high on-shelf availability, enabling the improvement of business profit in retail stores.
Performance analysis of uplink MC-CDMA/TDD systems with pre-compensation (2006)

Multi-carrier code division multiple access (MC- CDMA) can obtain good frequency Rake diversity effect and has been widely accepted as one of the promising multiple access methods. In this paper, a novel power-limited pre-compensation method in MC-CDMA/TDD systems, which can avoid pilot insertion on the uplink and increase the spectral/power efficiency, is described. Only the phase of signal is pre-distorted before transmission at the mobile station's transmitter to keep the transmission power constant. The BER performances of this system is analyzed and the numerical results are given.
Data from T Cell Receptor Genotyping and <i>HOXA/TLX1</i> Expression Define Three T Lymphoblastic Lymphoma Subsets which Might Affect Clinical Outcome (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; T lymphoblastic lymphomas (T-LBL) are rare disorders of immature T cells which predominantly involve the mediastinum. Their oncogenic pathways and prognostic variables are not clear.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; We undertook a retrospective study of 41 cytoplasmic CD3+ T-LBL (nine cases aged &lt;16 years) by assessing stage of maturation arrest based on T cell receptor (TCR) immunogenotyping, immunohistochemistry, and quantification of the oncogenes thought to be important in immature T cell malignancies.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; Application of a TCR-based immunogenetic classification allowed the identification of three subcategories: 11 immature IM0/D-LBL showed no TCR or only incomplete &lt;i&gt;TCRD&lt;/i&gt; DJ rearrangement and corresponded to cytoplasmic CD3+ precursors of uncertain lineage. Sixteen mature TCRD&lt;sup&gt;del&lt;/sup&gt;-LBL showed biallelic &lt;i&gt;TCRD&lt;/i&gt; deletion and both &lt;i&gt;TCRG&lt;/i&gt; and &lt;i&gt;TCRB&lt;/i&gt; rearrangement, consistent with TCRαβ lineage restriction. Fourteen intermediate LBL (Int-LBL) showed complete &lt;i&gt;TCRD&lt;/i&gt; VDJ and &lt;i&gt;TCRG&lt;/i&gt; VJ rearrangement, with &lt;i&gt;TCRB&lt;/i&gt; VDJ rearrangement in the majority. All Int-LBL expressed &lt;i&gt;HOX11/TLX1&lt;/i&gt; or &lt;i&gt;HOXA9&lt;/i&gt; transcripts and a proportion of the latter were associated with &lt;i&gt;CALM-AF10&lt;/i&gt; or &lt;i&gt;NUP214-ABL&lt;/i&gt; fusion transcripts. IM0/D-LBL were restricted to adults with extrathymic disease and bone marrow involvement, whereas Int-LBL and TCRD&lt;sup&gt;del&lt;/sup&gt;-LBL were found in children and adults with predominantly thymic disease. In adults, the Int-LBL subgroup was associated with a significantly superior clinical outcome. This subgroup can be identified either by TCR immunogenotyping or &lt;i&gt;HOXA9/TLX1&lt;/i&gt; transcript quantification.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusion:&lt;/b&gt; Application of this molecular classification will allow the prospective evaluation of prognostic effects within pediatric and adult protocols.&lt;/p&gt;&lt;/div&gt;
Longitudinal Assessment of Lung Cancer Progression in Mice Using the Sodium Iodide Symporter Reporter Gene and SPECT/CT Imaging (2016)

Lung cancer has the highest mortality rate of any tissue-specific cancer in both men and women. Research continues to investigate novel drugs and therapies to mitigate poor treatment efficacy, but the lack of a good descriptive lung cancer animal model for preclinical drug evaluation remains an obstacle. Here we describe the development of an orthotopic lung cancer animal model which utilizes the human sodium iodide symporter gene (hNIS; SLC5A5) as an imaging reporter gene for the purpose of non-invasive, longitudinal tumor quantification. hNIS is a glycoprotein that naturally transports iodide (I-) into thyroid cells and has the ability to symport the radiotracer 99mTc-pertechnetate (99mTcO4-). A549 lung adenocarcinoma cells were genetically modified with plasmid or lentiviral vectors to express hNIS. Modified cells were implanted into athymic nude mice to develop two tumor models: a subcutaneous and an orthotopic xenograft tumor model. Tumor progression was longitudinally imaged using SPECT/CT and quantified by SPECT voxel analysis. hNIS expression in lung tumors was analyzed by quantitative real-time PCR. Additionally, hematoxylin and eosin staining and visual inspection of pulmonary tumors was performed. We observed that lentiviral transduction provided enhanced and stable hNIS expression in A549 cells. Furthermore, 99mTcO4- uptake and accumulation was observed within lung tumors allowing for imaging and quantification of tumor mass at two-time points. This study illustrates the development of an orthotopic lung cancer model that can be longitudinally imaged throughout the experimental timeline thus avoiding inter-animal variability and leading to a reduction in total animal numbers. Furthermore, our orthotopic lung cancer animal model is clinically relevant and the genetic modification of cells for SPECT/CT imaging can be translated to other tissue-specific tumor animal models.
Design of Variable Magnetization Pattern Machines for Dynamic Changes in the Back EMF Waveform (2019)

Variable magnetization pattern permanent magnet synchronous machines (VMP-PMSMs) capable of dynamic changes in the magnetization spatial distribution are discussed in this paper. VMP-PMSMs are able to change the harmonic components in the air gap magnetic flux density due to the magnet by intentional demagnetization; hence, they can effectively manipulate the torque ripples and losses according to the required operating points. The objective of this paper is to provide a procedure to design VMP-PMSMs that can have both the sinusoidal and the trapezoidal back EMF waveforms by switching magnetization pattern. The performance of the designed VMP-PMSM following the reported procedure is confirmed through experiments as well as finite element analysis (FEA) simulations in terms of the back EMF shaping, torque ripple reduction, and loss reduction. Loss analysis of VMP-PMSMs is also given as contrasting with variable flux permanent magnet machines (VF-PMSMs), showing that VMP-PMSMs can reduce more losses than VF-PMSMs with the same torque density.
An Inter-Vehicle Geocasting Algorithm for Vehicular Cooperative Collision Warning System using DSRC (2010)

This paper presents an inter-vehicle geocasting and collision warning algorithm to accomplish multihop and collision avoidance in cooperative driving and data exchanged based on GPS positioning and dedicated short range communication (DSRC). The concept of cooperative collision warning (CCW) system provides warning or situation awareness to drivers based on broadcast messaging the motions of neighboring vehicles obtained by one-way communication from other vehicles. The proposed system has the advantage of omnidirectional transmitting/receiving functions of DSRC module that provides 360-degree coverage in own surveillance region. The scenario of CCW system is mainly applied on group trips; moreover, the developed algorithm has the ability of message broadcasting and collision point estimation. This article concerns message geocasting and collision warning in inter-vehicle communication. Indeed, each CCW system can show other vehicles on the geographical map, and furthermore the developed inter-vehicle geocasting algorithm is the key point in remote surveillance, while some vehicles move away or turn into the roadway or intersection. The development system integrates DSRC and GPS with embedded system into CCW system. From the positioning data and vehicular information, this paper provides a conflict detection algorithm to do time separation and remote warning with error bubble consideration. The proposed system is carried out with theoretical application and hardware integration, and the result shows cooperative driving approach applicability using vector geocasting method. Some experiments are also scheduled about packet loss and latency by static tests, in which vehicles stop in fixed position away from 0 to 200 m.
Glass Transition Behavior of Single-Walled Carbon Nanotube−Polystyrene Composites (2009)

A variety of measurements using a differential scanning calorimeter were used to probe how single-walled carbon nanotubes (SWCNTs) affect polymer dynamics associated with the glass transition. Tubes were dispersed in N,N-dimethylformamide containing dissolved polystyrene, and precipitation was quickly forced by the addition to large amounts of water. The percolation threshold was found to be less than 0.5 wt %, indicating good dispersion of the tubes. The glass transition temperature (Tg) increased at low nanotube fractions to a constant value about 6−7 °C higher than the Tg of pure polystyrene, and did not change further as the nanotube amount changed from 1 to 30 wt %. The heat capacity change at the glass transition decreased with increasing nanotube concentration, except at very high SWCNT contents (>10 wt %), where the heat capacity change began to increase. The decrease of heat capacity at low nanotube contents indicates that a fraction of the polymer is made immobile via the addition of SWCNTs; while the large increase at high contents suggests that nanotubes are participating in the molecular motion that is the glass transition. The relaxation rate as determined by the change in limiting fictive temperature with annealing time showed the same qualitative behavior as the glass transition, a decrease in polymer mobility at very low nanotube fractions followed by a constant value. Surprisingly, one measure of the activation energy increased at low nanotube contents (<0.5 wt %) and dropped at high nanotube contents to an energy that looks to be slightly higher than that for pure polystyrene. In other words, in the region where the formation of a continuous network occurs the activation energy is highest.
Dempster-Shafer's theory of evidence applied to structured documents (1997)

article Free Access Share on Dempster-Shafer's theory of evidence applied to structured documents: modelling uncertainty Author: Mounia Lalmas Department of Computing Science, University of Glasgow, G12 8QQ Scotland Department of Computing Science, University of Glasgow, G12 8QQ ScotlandView Profile Authors Info & Claims ACM SIGIR ForumVolume 31Issue SIDecember 1997 pp 110–118https://doi.org/10.1145/278459.258546Published:01 July 1997Publication History 56citation1,216DownloadsMetricsTotal Citations56Total Downloads1,216Last 12 Months13Last 6 weeks1 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my Alerts New Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteeReaderPDF
High‐efficiency light‐collection optics for lamp‐based projection TV (2007)

Abstract— A new light‐collection optics has been developed that enhances the luminance of projection TV which use lamps as the light source. The conventional optical system consists of an elliptical reflector and a flat‐surface front glass, but these systems cannot sufficiently collect the beams coming from the light source, and they cause loss in the coupling with the light pipe. To solve this problem, we devised a new optical system through a structure of an aspherical reflector and an aspherical front glass. This new optical system concentrates the beams coming from the light source to a smaller point which improves the coupling efficiency. Thus, we have successfully increased the luminance of the projection TV by approximately 10%. This paper reports the design principles of the new optical system and the results of a prototype experiment.
Subspace Structure-Aware Spectral Clustering for Robust Subspace Clustering (2019)

Subspace clustering is the problem of partitioning data drawn from a union of multiple subspaces. The most popular subspace clustering framework in recent years is the graph clustering-based approach, which performs subspace clustering in two steps: graph construction and graph clustering. Although both steps are equally important for accurate clustering, the vast majority of work has focused on improving the graph construction step rather than the graph clustering step. In this paper, we propose a novel graph clustering framework for robust subspace clustering. By incorporating a geometry-aware term with the spectral clustering objective, we encourage our framework to be robust to noise and outliers in given affinity matrices. We also develop an efficient expectation-maximization-based algorithm for optimization. Through extensive experiments on four real-world datasets, we demonstrate that the proposed method outperforms existing methods.
A promising nanocomposite from CNTs and nano-ceria: nanostructured fillers in polyurethane coatings for surface protection (2015)

The balanced combination of nanostructured carbon materials and metal oxide nanoparticles has been considered as an efficient reinforcement material in developing next-generation multifunctional coatings.
Low Cost, Injection Molded 120 Gbps Optical Backplane (2011)

A low cost, <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">blind mate</sub> , injection molded optical backplane is presented. The optical backplane consists of a 12 channel optical broadcast bus operating at 10 Gbps/channel with six blind mate optical output ports spaced 1U apart.
Numerical simulation of vacuum-ultraviolet irradiation of dielectric layers (2010)

Vacuum-ultraviolet irradiation produces trapped charges in dielectrics. The trapped charges often generate self-consistent electric fields. A Monte Carlo simulation coupled with a Poisson equation solver is used to model the relationship between the irradiation photon flux and electrostatic potential. The simulation includes photoconduction, photoemission, photoinjection, and the effects of self-consistent electric fields. Calculations show that photoemission and photoinjection are responsible for changes in the electric potential as photon dose or dielectric thicknesses are varied. Experimental surface-potential measurements were made to compare the results of the simulation.
Pre-Reducing Process Kinetics to Recover Metals from Nickel Leach Waste Using Chelating Resins (2018)

The main problem of the separation process from nickel mining using the ion exchange technique is the presence of iron, which precipitates in pH above 2.00 and causes coprecipitation of copper and cobalt. Chelating resins have the main advantage of being selected for a specific metal present in solution. Studies have been developed to increase the efficiency of metals recovery using chemical reduction and the ion exchange process to recover metals. The aim of this work was to use sodium sulfite as a reducing agent to convert Fe(III) to Fe(II). Chelating resins Lewatit® TP 207, selective for copper, and Lewatit® TP 220, selective for nickel and cobalt, were studied. Batch experiments were performed to study the effect of pH with and without sodium sulfite. Results indicated that the industrial process has increased efficiency when the reducing process is applied.