gebhart/patrepeval huggingface dataset:
Dynamics and evolution of continental margin clinoform systems (2020)

&amp;lt;p&amp;gt;Clinoforms are aquatic sedimentary features commonly associated with strata prograding from a shallower water depth into a deeper water depth. They are very sensitive to changes in water depth, rapidly moving along the shelf in response to sea level changes. &amp;amp;#160;By reconstructing the initial clinoform geometry of buried clinoforms, an estimate of the paleo water depth (PWD) can be made. When this is done for several subsequent clinoform sets the amounts and rates of bathymetric changes can be calculated.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Here we present a novel approach to estimate clinoform parameters and depositional depths for continental margin clinoforms using seismic reflections, wellbore and biostratigraphy data. Seismic interpretation of three relatively east-west regional full-stack seismic reflection data from the continental margin of the western Barents Sea revealed twelve Late Cenozoic horizons. The clinoform shapes have been restored by removing the effects of compaction and flexural isostasy (backstripping). This includes the effects of glacial/interglacial scenarios on horizons with strong glaciomarine seismic indications.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Based on the reconstructed clinoform geometries we use empirical relationships from literature between clinoform geometry and depositional depth to estimate PWD values. In these analyses it is possible to estimate the PWD of the upper rollover point and the toe point by measuring the bottomset height, foreset height and topset height. A sensitivity analysis study has also been done on several different scenarios, varying elastic thickness, decompaction and net to gross ratio. Comparison with biostratigraphic water depth estimates indicate that PWD estimates revealed from clinoform parameters give reliable results.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;Any mismatch between the backstripped PWD values and the PWD values derived from the clinoform geometry can then be attributed to geological processes not included in the backstripping process. Among others, these could be explained by rifting, thermal effects in the lithosphere, faulting or eustatic sea level changes. This allows the quantification of the magnitude of these large-scale crustal processes through time.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;We will demonstrate that this method can further constrain the PWD on the continental margin clinoform system and thus can help to improve the understanding of the interplay between sedimentary processes and large-scale crustal processes. Furthermore, the PWD estimates will be a reliable input for further analysis of source-to-sink and stratigraphic forward modeling studies as well as reservoir and source rocks prediction on the petroleum development and exploration.&amp;lt;/p&amp;gt;&amp;lt;p&amp;gt;&amp;amp;#160;&amp;lt;/p&amp;gt;
Accurate Color Reproduction of CRT Displayed Images as Projected 35mm Slides (1994)

Accurate color reproduction of images presented on a computer-controlled CRT display as projected 35mm transparencies is a complicated procedure requiring the characterization and control of several imaging processes and application of appropriate color-appearance modeling to account for the changes in viewing conditions. This paper reviews a process for image-recorder characterization, projection-system characterization, and testing of color-appearance models for this application.
Schizophrenia, Alzheimer's Disease, and Anti-inflammatory Agents (1996)

Some recent postmortem reports raise the possibility that Alzheimer-type pathology may be 6 to 12 times higher in elderly schizophrenia patients than in general population. One study indicates that neuroleptic treatment may be an important contributor. Other reports, however, suggest that cognitive impairment in elderly schizophrenia patients is seldom due to Alzheimer-type pathology, indicating that more detailed follow-up studies are needed. Since multiple epidemiological studies show that Alzheimer's disease is less prevalent in patients with medical conditions requiring anti-inflammatory drugs than in the general population, anti-inflammatory medication might be considered as an adjuvant to chronic neuroleptic treatment in elderly schizophrenia patients showing early signs of Alzheimer-type memory deficits.
Airway Gene Expression as a Molecular Phenotype of COPD (2012)

Department of Medicine, Section of Computational Biomedicine, Boston University Medical Center, Boston, Massachusetts; Department of Pulmonology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts; The Pulmonary Center, Boston University Medical Center, Boston, Massachusetts; Department of Pathology and Laboratory Medicine, Boston University Medical Center; Bioinformatics Program, Boston University, Boston, Massachusetts; British Columbia Cancer Agency, Vancouver, British Columbia, Canada; The James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, Vancouver, British Columbia, Canada; Department of Pathology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Department of Pulmonology, Leiden University Medical Center, Leiden, The Netherlands; and Department of Respiratory Medicine, Academic Medical Centra, University of Amsterdam, Amsterdam, The Netherlands
High performance concentrating photovoltaic module designs for utility scale power generation (2009)

The Boeing Company Phantom Works has developed three different prototype photovoltaic concentrator arrays since March 2007. Identified as Prototype A, B and C, the experimentally proven technical characteristics of each design are presented. The concentrator designs utilize a 1 cm<sup>2</sup> multi-junction solar cell assembly in conjunction with SMS non-imaging optical designs [1, 2] manufactured with low-cost mass-producible technologies. Prototype A is an on-axis XR optical concentrator with a 733x geometrical concentration demonstrating a &plusmn; 1.73&deg; acceptance angle and 23.7% conversion efficiency. Prototype B is an off-axis free-form XR optical concentrator with a 810x geometrical concentration demonstrating a &plusmn; 1.32&deg; acceptance angle and 25.3% conversion efficiency. Prototype C is the most recent off-axis free-form XR optical concentrator with a 801x geometrical concentration and a theoretical &plusmn;1.80&deg; acceptance angle demonstrating a conversion efficiency greater than 27.0%. Prototype C is also the basis for the Boeing Proof of Design (POD) module, demonstrating an acceptance angle of &plusmn;1.48&deg; and a conversion efficiency of 29.4% (as of May 8, 2009). Manufacturability has been paramount during the design process, resulting in high performance concentrating photovoltaic modules using production quality components.
Adaptation of two types of processing gains for UWB impulse radio wireless sensor networks (2007)

Ultrawideband impulse radio systems offer two kinds of processing gains that can be adapted based on the interference level in the system so that quality of service requirements are fulfilled. An adaptive assignment scheme for two types of multiple-access parameters in cluster-based wireless sensor networks is investigated. A mathematical framework is developed for asynchronous communications using a Gaussian approximation method to model the multiple-access interference in two cases: one with fixed frame duration, where the goal is to increase the average throughput, and the other with fixed symbol duration, where the goal is to increase the network lifetime. Extension of the analysis to multipath channels is carried out, and the validity of the Gaussian approximation is investigated using the Kullback-Leibler distance.
Ovarian teratoma in a woodchuck (Marmota monax) with hepatocellular carcinoma: radiologic and pathologic features (2020)

Ovarian teratoma should be considered in the differential diagnosis of ovarian or abdominal masses in woodchucks. The tumor displayed mature tissue derived from all three germ layers. CT, ultrasound, and MRI findings were presented in detail and matched the typical imaging appearance of teratomas.
Resultados del censo nacional de 2017 (aguilucho pálido y cenizo) (2019)

Trabajo presentado al XV Congreso del Grupo Ibérico de Aguiluchos (GIA), celebrado en el Centro Nacional de Educación Ambiental de Valsaín (La Granja de San Ildefonso – Segovia) del 22 al 24 de noviembre de 2019.
Modulation of Akt/mTOR Signaling Overcomes Sunitinib Resistance in Renal and Prostate Cancer Cells (2012)

Tyrosine kinase inhibitors exhibit impressive activity against advanced renal cell carcinoma. However, recent clinical studies have shown an equivocal response to sunitinib in patients with castration-resistant prostate cancer. The tumor suppressor PTEN acts as a gatekeeper of the phosphoinositide 3-kinase (PI3K)/Akt/mTOR cell-survival pathway. Our experiments showed that PTEN expression inversely correlates with sunitinib resistance in renal and prostate cancer cells. Restoration of PTEN expression markedly increases sensitivity of tumor cells to sunitinib both in vitro and in vivo. In addition, pharmacologic manipulation of PI3K/Akt/mTOR signaling with PI3K/mTOR inhibitor, GDC-0980, mTOR inhibitor, temsirolimus, or pan-Akt inhibitor, GSK690693, was able to overcome sunitinib resistance in cancer cells. Our findings underscore the importance of PTEN expression in relation to sunitinib resistance and imply a direct cytotoxic effect by sunitinib on tumor cells in addition to its antiangiogenic actions.
The N-terminal SH2 Domains of Syk and ZAP-70 Mediate Phosphotyrosine-independent Binding to Integrin β Cytoplasmic Domains (2002)

Syk and ZAP-70 form a subfamily of nonreceptor tyrosine kinases that contain tandem SH2 domains at their N termini. Engagement of these SH2 domains by tyrosine-phosphorylated immunoreceptor tyrosine-based activation motifs leads to kinase activation and downstream signaling. These kinases are also regulated by beta3 integrin-dependent cell adhesion via a phosphorylation-independent interaction with the beta3 integrin cytoplasmic domain. Here, we report that the interaction of integrins with Syk and ZAP-70 depends on the N-terminal SH2 domain and the interdomain A region of the kinase. The N-terminal SH2 domain alone is sufficient for weak binding, and this interaction is independent of tyrosine phosphorylation of the integrin tail. Indeed, phosphorylation of tyrosines within the two conserved NXXY motifs in the integrin beta3 cytoplasmic domain blocks Syk binding. The tandem SH2 domains of these kinases bind to multiple integrin beta cytoplasmic domains with varying affinities (beta3 (Kd = 24 nm) > beta2 (Kd = 38 nm) > beta1 (Kd = 71 nm)) as judged by both affinity chromatography and surface plasmon resonance. Thus, the binding of Syk and ZAP-70 to integrin beta cytoplasmic domains represents a novel phosphotyrosine-independent interaction mediated by their N-terminal SH2 domains.
Neural computing for scientific computing applications (2017)

Neural computing has been identified as a computing alternative in the post-Moore's Law era, however much of its attention has been directed at specialized applications such as machine learning. For scientific computing applications, particularly those that often depend on supercomputing, it is not clear that neural machine learning is the exclusive contribution to be made by neuromorphic platforms. In our presentation, we will discuss ways that looking to the brain as a whole and neurons specifically can provide new sources for inspiration for computing beyond current machine learning applications. Particularly for scientific computing, where approximate methods for computation introduce additional challenges, the development of non-approximate methods for neural computation is potentially quite valuable. In addition, the brain's dramatic ability to utilize context at many different scales and incorporate information from many different modalities is a capability currently poorly realized by neural machine learning approaches yet offers considerable potential impact on scientific applications.
Faculty Opinions recommendation of Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis. (2004)

Read the full review for this Faculty Opinions recommended article: Coordinate expression and trans presentation of interleukin (IL)-15Ralpha and IL-15 supports natural killer cell and memory CD8+ T cell homeostasis.
A 0.1pJ/b 5-to-10Gb/s charge-recycling stacked low-power I/O for on-chip signaling in 45nm CMOS SOI (2013)

Compact low-power signaling schemes to drive on-chip interconnects are needed for processor chips where high-bandwidth data buses connect processor cores and on-chip cache. Since a significant portion of the signaling power is dynamic power spent on driving long wires, reducing the signal swing improves power efficiency [1-3]. In addition, charge-recycling techniques reduce signal swing by stacking circuits with regular and predictable data switching activities, such as logic circuits [4] and clocking circuits [5]. Unlike conventional schemes, low-swing I/O that leverages charge-recycling techniques offers the potential for quadratic power reduction. We present a compact low-power I/O for on-chip signaling using charge-recycling stacked drivers and compact voltage regulators/converters. A receiver circuit modified from a parametric amplifier-based design [6] further improves the area and power efficiency.
Photo-Assisted Corona-Charge Characterization of Wide Bandgap Interfaces with Deep Traps Invisible in Standard C-V (2020)

Wide bandgap semiconductor technology has been generating a great deal of attention due to its fundamental advantages in high power electronics. Understanding and effective control of interfacial properties belong to a group of critical issues requiring progress. In this work, we report progress in wide bandgap interface characterization, achieved using photo-ionization of deep traps under a non-equilibrium condition created by corona-charge bias in deep depletion. This characterization capability is demonstrated on oxidized n-type epitaxial SiC with deep interfacial traps invisible in standard C-V. These traps, initially present at high density, are shown to be reduced by half after a wet anneal. The photo-ionization technique is incorporated in commercially available non-contact C-V (CnCV) metrology [1,2] providing a non-invasive, cost and time saving metrology that benefits development research as well as device fabrication.
Energy Minimization of a QAM System (2007)

In this paper, an energy minimization problem for a quadrature amplitude modulation (QAM) system with automatic repeat request (ARQ) is considered. We formulate an optimization problem with constellation size and transmit power as the variables. We give an efficient and accurate geometric programming (GP) approximation to the problem and illustrate the solution using a numerical example. We learn that the transmit power or equivalently bit error rate (BER) should be carefully chosen for minimal energy. Our analysis provides guidelines for setting the BER in an energy optimal way for various packet lengths.
Simple bounds for a transient queue (2011)

Bounds on performance of a queueing model can provide useful information to guarantee quality of service for communication networks. We study the bounds on the mean delay in a transient GI/GI/1 queue given the first two moments of the service time and the inter-arrival time, respectively. We establish a simple upper-bound, which then is used to show that the true transient mean-delay is at most four times larger than an asymptotic diffusion-approximation. We also prove that the tight lower-bound is zero as long as the service time and the inter-arrival time have finite variance and the load is below one. Tightness of the trivial lower-bound is in contrast to the stationary mean-delay, which has strictly positive lower-bound when the service time is sufficiently variable. We also show how our results can be applied to analyze the transient mean delay of packets in the real-world Internet.
Correction to Exploring the Effect of Conjugation Site and Chemistry on the Immunogenicity of an anti-Group B Streptococcus Glycoconjugate Vaccine Based on GBS67 Pilus Protein and Type V Polysaccharide (2015)

ADVERTISEMENT RETURN TO ISSUEPREVCorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Exploring the Effect of Conjugation Site and Chemistry on the Immunogenicity of an anti-Group B Streptococcus Glycoconjugate Vaccine Based on GBS67 Pilus Protein and Type V PolysaccharideAlberto Nilo, Irene Passalacqua, Monica Fabbrini, Martin Allan, Aimee Usera, Filippo Carboni, Barbara Brogioni, Alfredo Pezzicoli, Jennifer Cobb, Maria Rosaria Romano, Immaculada Margarit, Qi-Ying Hu, Francesco Berti, and Roberto Adamo*Cite this: Bioconjugate Chem. 2015, 26, 10, 2167Publication Date (Web):September 10, 2015Publication History Published online10 September 2015Published inissue 21 October 2015https://pubs.acs.org/doi/10.1021/acs.bioconjchem.5b00480https://doi.org/10.1021/acs.bioconjchem.5b00480correctionACS PublicationsCopyright © 2015 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views755Altmetric-Citations1LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (228 KB) Get e-AlertscloseSUBJECTS:Carbohydrates,Chemical structure,Isolation,Vaccination Get e-Alerts
Ammonium Fluoride Anti-stiction Treatments For Polysilicon Microstructures (2005)

A surface treatment for stiction reduction is described which has been shown to passivate surface micromachined micromechanical structures. Surface passivation is accomplished during the etching of silicon by ammonium fluoride (NH/sub 4/F) by means of a high quality hydrogen-termination of surface dangling bonds. The NH/sub 4/F treatment is integrated directly with the conventional release process, and is compatible with super critical drying techniques. Use of a cantilever beam array specifically designed for the measurement of in-use stiction showed a decrease in the work of adhesion from 42 mJ/m/sup 2/ for the hydrophilic release to less than, 0.3 mJ/m/sup 2/ for the NH/sub 4/F release processes. Encapsulation in a dry ambient will be necessary, as the hydrogen-terminated surface oxidizes after about one week in room air.
Semiconductor Waveguide Isolators (2008)

The monolithic integration of optical isolators with semiconductor lasers has remained an unsolved problem in photonics. Challenges associated with fabrication and incorporation of new materials with conventional III-V semiconductors have resulted in many novel approaches. This paper discusses these different approaches and also presents a summary of our own work on the monolithic integration of optical isolators.
Photoluminescence of a ‐plane GaN: comparison between MOCVD and HVPE grown layers (2006)

Abstract We report on the emission properties of nonpolar a ‐plane GaN layers grown by metalorganic chemical vapor deposition (MOCVD) and hydride vapor phase epitaxy (HVPE). Together with the typical band edge exciton emission, the low‐temperature photoluminescence spectra reveal several emission bands in the spectral range 3.29‐3.42 eV. These emissions appear with different intensities in layers grown by different techniques and show different thermal quenching and recombination dynamics. The 3.42 eV and 3.35 eV emissions are found to be of an intrinsic origin and are associated with carriers localized at stacking faults. The emission at 3.29 eV, which is present only in MOCVD layers, shows a donor‐acceptor pair behavior suggesting that impurities attached to structural defects are involved. (© 2006 WILEY‐VCH Verlag GmbH &amp; Co. KGaA, Weinheim)
Fenofibrate improves vascular endothelial function and contractility in diabetic mice (2018)

Fenofibrate, a peroxisome proliferator-activated receptors α (PPARα) agonist, reduces vascular complications of diabetic patients but its protective mechanisms are not fully understood. Here we tested the hypothesis that fenofibrate improves vascular endothelial dysfunction by balancing endothelium-dependent relaxation and contractility of the aorta in diabetes mellitus (DM). In streptozotocin-induced diabetic mice, eight weeks of fenofibrate treatment (100 mg/Kg/d) improved endothelium dependent relaxation in the macro- and microvessels, increased nitric oxide (NO) levels, reduced renal damage markers and effects of the vasoconstrictor prostaglandin. Levels of superoxide dismutase and catalase were both reduced and hydrogen peroxide was increased in vehicle-treated DM, but these changes were reversed by fenofibrate treatment. Vasodilation of the aorta after fenofibrate treatment was reversed by PPARα or AMPKα inhibitors. Western blots showed that fenofibrate treatment elevated PPARα expression, induced liver kinase B1 (LKB1) translocation from the nucleus to the cytoplasm and activated AMP-activated protein kinase-α (AMPKα), thus activating endothelial NO synthase (eNOS). Also, fenofibrate treatment decreased NF-κB p65 and cyclooxygenase 2 proteins in aortas. Finally, incubation with indomethacin in vitro improved aortic contractility in diabetic mice. Overall, our results show that fenofibrate treatment in diabetic mice normalizes endothelial function by balancing vascular reactivity via increasing NO production and suppressing the vasoconstrictor prostaglandin, suggesting mechanism of action of fenofibrate in mediating diabetic vascular complications.
Experimental Study of Fluid Jet Mixing at Supercritical Conditions (2010)

Subcritical and supercritical fluids were injected in an inert gaseous atmosphere. Density distribution was measured and density-gradient profiles were inferred from the experimental data. A novel method was applied for the detection of detailed structures throughout the entire jet center plane. The core lengths were measured for each of the cases and correlated with previous visualization results. An eigenvalue approach was taken to determine the location of maximum gradients. The results show a significant influence of chamber-to-injectant density ratio on the core length in the supercritical domain, unlike the subcritical conditions.