gebhart/patrepeval huggingface dataset:
The relightables (2019)

We present "The Relightables", a volumetric capture system for photorealistic and high quality relightable full-body performance capture. While significant progress has been made on volumetric capture systems, focusing on 3D geometric reconstruction with high resolution textures, much less work has been done to recover photometric properties needed for relighting. Results from such systems lack high-frequency details and the subject's shading is prebaked into the texture. In contrast, a large body of work has addressed relightable acquisition for image-based approaches, which photograph the subject under a set of basis lighting conditions and recombine the images to show the subject as they would appear in a target lighting environment. However, to date, these approaches have not been adapted for use in the context of a high-resolution volumetric capture system. Our method combines this ability to realistically relight humans for arbitrary environments, with the benefits of free-viewpoint volumetric capture and new levels of geometric accuracy for dynamic performances. Our subjects are recorded inside a custom geodesic sphere outfitted with 331 custom color LED lights, an array of high-resolution cameras, and a set of custom high-resolution depth sensors. Our system innovates in multiple areas: First, we designed a novel active depth sensor to capture 12.4 MP depth maps, which we describe in detail. Second, we show how to design a hybrid geometric and machine learning reconstruction pipeline to process the high resolution input and output a volumetric video. Third, we generate temporally consistent reflectance maps for dynamic performers by leveraging the information contained in two alternating color gradient illumination images acquired at 60Hz. Multiple experiments, comparisons, and applications show that The Relightables significantly improves upon the level of realism in placing volumetrically captured human performances into arbitrary CG scenes.
Optical Control of Small Molecule-Induced Protein Degradation (2020)

As an emerging approach to protein perturbation, small molecule-induced protein degradation has gained significant attention as both a chemical tool and a potential therapeutic. To enable discrete control over its function, we have developed a broadly applicable approach for the optical activation of small molecule-induced protein degradation. By installing two different photolabile protecting groups, so-called caging groups, onto two different ligands recruiting Von Hippel-Lindau (VHL) and cereblon (CRBN) E3 ubiquitin ligases, our strategy enables light-triggered protein degradation for any small molecule warhead.
Novel design and synthesis of a radioiodinated glycolipid analog as an acceptor substrate for N‐acetylglucosaminyltransferase V (2013)

Guided by the known molecular recognition interactions between N-acetylglucosaminyltransferase V (GnT-V) and certain synthetic substrates, we synthesized a radiolabeled double-stranded glycolipid composed of a long-chain alkyl unit and a radioiodinated phenylalkyl unit, [(125)I]-2-[N-(2-hydroxy-3-hexadecyloxy)propyl-15-(4-iodophenyl)pentadecanecarboxamido]ethyl 2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→2)-α-D-mannopyranosyl-(1→6)-β-D-glucopyranoside ([(125)I]2), as a novel intravital glycolipid mimic substrate of GnT-V. The radioactive iodine ((125)I) was incorporated via iododestannylation of the phenyltributyltin derivative, 2-[N-(2-acetoxy-3-hexadecyloxy)propyl-15-(4-tributylstannylphenyl)pentadecanecarboxamido]ethyl 3,4,6-tri-O-acetyl-2-acetamido-2-deoxy-β-D-glucopyranosyl-(1→2)-3,4,6-O-acetyl-α-D-mannopyranosyl-(1→6)-2,3,4-tri-O-acetyl-β-D-glucopyranoside (26). Subsequent deacetylation at the final step afforded [(125)I]2.
Dynamic-threshold CMOS SRAM cells for fast, portable applications (2002)

A novel quad-rail CMOS SRAM cell architecture that doubles cell read current, improves cell static noise margin (SNM) by 70%, increases cell immunity to SER and lowers cell standby power by over an order of magnitude is proposed. These improvements are achieved by implementing a scheme of WL transition triggered pulses on source and substrate terminals of cell inverter transistors that share a common WL.
LDL extracellular vesicle coagulation protein levels change after initiation of statin therapy. Findings from the METEOR trial (2018)

Rosuvastatin increases LDL-EV coagulation proteins plasminogen and VWF in patients with subclinical atherosclerosis, an effect that is different from the effect of rosuvastatin on the same proteins in serum. This identifies LDL-EVs as a newly detected possible intermediate between statin therapy and coagulation.
Towards a Common Notion of Privacy Leakage on Public Database (2010)

Two different approaches to defining a notion of database privacy, the generalization method and the perturbation method, have been independently studied. These two approaches are significantly different, making it hard to compare related research. In this paper, we propose a unified model that is based on the perturbation method, but which is applicable to generalized data sets. In particular, this model applies the notion of differential privacy to data sets that satisfy k-anonymity. We demonstrate this approach through a simple case study. This is a first step towards a common notion for protecting database privacy.
Antigen Discovery and Therapeutic Targeting in Hematologic Malignancies (2017)

Historically, immune-based therapies have played a leading role in the treatment of hematologic malignancies, with the efficacy of stem cell transplantation largely attributable to donor immunity against malignant cells. As new and more targeted immunotherapies have developed, their role in the treatment of hematologic malignancies is evolving and expanding. Herein, we discuss approaches for antigen discovery and review known and novel tumor antigens in hematologic malignancies. We further explore the role of established and investigational immunotherapies in hematologic malignancies, with a focus on personalization of treatment modalities such as cancer vaccines and adoptive cell therapy. Finally, we identify areas of active investigation and development. Immunotherapy is at an exciting crossroads for the treatment of hematologic malignancies, with further investigation aimed at producing effective, targeted immune therapies that maximize antitumor effects while minimizing toxicity.
Actively Secure Private Function Evaluation. (2014)

Abstract. We propose the first general framework for designing actively secure private function eval-uation (PFE), not based on universal circuits. Our framework is naturally divided into pre-processing and online stages and can be instantiated using any generic actively secure multiparty computation (MPC) protocol. Our framework helps address the main open questions about efficiency of actively secure PFE. On the theoretical side, our framework yields the first actively secure PFE with linear complexity in the circuit size. On the practical side, we obtain the first actively secure PFE for arithmetic circuits with O(g · log g) complexity where g is the circuit size. The best previous construction (of practical interest) is based on an arithmetic universal circuit and has complexity O(g5). We also introduce the first linear Zero-Knowledge proof of correctness of “extended permutation ” of ciphertexts (a generalization of ZK proof of correct shuffles) which maybe of independent interest.
Towards robustness under occlusion for face recognition (2021)

In this paper, we evaluate the effects of occlusions in the performance of a face recognition pipeline that uses a ResNet backbone. The classifier was trained on a subset of the CelebA-HQ dataset containing 5,478 images from 307 classes, to achieve top-1 error rate of 17.91%. We designed 8 different occlusion masks which were applied to the input images. This caused a significant drop in the classifier performance: its error rate for each mask became at least two times worse than before. In order to increase robustness under occlusions, we followed two approaches. The first is image inpainting using the pre-trained pluralistic image completion network. The second is Cutmix, a regularization strategy consisting of mixing training images and their labels using rectangular patches, making the classifier more robust against input corruptions. Both strategies revealed effective and interesting results were observed. In particular, the Cutmix approach makes the network more robust without requiring additional steps at the application time, though its training time is considerably longer. Our datasets containing the different occlusion masks as well as their inpainted counterparts are made publicly available to promote research on the field.
Remote Activation of Nickel Catalysts for Ethylene Oligomerization (2005)

Ferngesteuert: Ein neuartiges Moleküldesign wird verwendet, um die Aktivierung von Übergangsmetall-basierten Initiatoren für die Ethylenpolymerisation und -oligomerisierung mithilfe einer über eine elektronisch delokalisierte Struktureinheit wirkenden Lewis-Säure zu untersuchen. Verbindung 1 mit einer Lewis-Säure-Einheit auf der dem eintretenden Substrat gegenüberliegenden Seite ist bei der Ethylenoligomerisierung hoch aktiv.
Centella asiaticaExtract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action (2012)

Centella asiatica (CA), commonly named gotu kola, is an Ayurvedic herb used to enhance memory and nerve function. To investigate the potential use of CA in Alzheimer's disease (AD), we examined the effects of a water extract of CA (GKW) in the Tg2576 mouse, a murine model of AD with high β-amyloid burden. Orally administered GKW attenuated β-amyloid-associated behavioral abnormalities in these mice. In vitro, GKW protected SH-SY5Y cells and MC65 human neuroblastoma cells from toxicity induced by exogenously added and endogenously generated β-amyloid, respectively. GKW prevented intracellular β-amyloid aggregate formation in MC65 cells. GKW did not show anticholinesterase activity or protect neurons from oxidative damage and glutamate toxicity, mechanisms of current AD therapies. GKW is rich in phenolic compounds and does not contain asiatic acid, a known CA neuroprotective triterpene. CA thus offers a unique therapeutic mechanism and novel active compounds of potential relevance to the treatment of AD.
A SUPERVISED LEARNING APPROACH TO AMBIENCE EXTRACTION FROMMONO RECORDINGS FOR BLIND UPMIXING (2008)

A supervised learning approach to ambience extraction from onechannel audio signals is presented. The extracted ambient signals are applied for the blind upmixing of musical audio recordings to surround sound formats. The input signal is processed by means of short-term spectral attenuation. The spectral weights are computed using a low-level feature extraction process and a neural network regression method. The multi-channel audio signal is generated by feeding the computed ambient signal into the rear channels of a surround sound system.
Alicyclic photoresists for CO 2 -based microlithography at 157 nm (2003)

Norbornene-based monomers were synthesized to include fluorinated moieties and/or chemical amplification switching groups. Polymers to be used as potential resist materials were synthesized from these monomers by addition polymerization using allylpalladium chloride dimmer. Monomers and polymers have been identified and partially characterized for important lithographic properties.
Study of xylan and cellulose interactions monitored with solid-state NMR and QCM-D (2019)

Abstract Development of physical properties of bleached eucalyptus kraft pulp is typically based on the refining process. However, many studies have reported that xylan deposition is a viable alternative. As the mechanisms of xylan and cellulose interactions are not clear, the main goal of this study was to achieve a better understanding of these interactions. Considering that a sample of pulp enriched with xylan is a very complex matrix, a model system was developed. Cellulosic thin films were prepared by spincoating and the Langmuir-Schaefer (LS) method from trimethylsilylcellulose (TMSC). Their interactions with xylan were analyzed using the quartz crystal microbalance with dissipation (QCM-D) monitoring technique. The topological changes on cellulose were studied using atomic force microscopy (AFM). For the 13 C solid-state nuclear magnetic resonance (NMR) studies, samples were prepared using commercial microcrystalline cellulose (MCC) and xylan. The xylan was extracted from bleached birch kraft pulp using a cold caustic extraction (CCE) method. The QCM-D monitoring showed deposition only with higher concentrations of xylan solution (1 mg · l −1 ) for the LS method. The AFM images showed that xylan deposits as agglomerates on the cellulose surface, and the NMR experiments showed that there are interactions for the more ordered region of the cellulose fiber and for the less-ordered region.
Inter-eNB Flow Control for Heterogeneous Networks with Dual Connectivity (2015)

In scenarios where the macro and small cells are deployed at different carrier frequencies, dual connectivity (DC) is a promising technique to serve the users with higher data rates. In this paper we focus on the case where the macro and small cell eNBs are inter-connected with traditional backhaul connections characterized by certain latency, assuming independent radio resource management (RRM) functionalities residing in each eNB. In order to fully harvest the gain provided by DC, an efficient flow control of data between the involved macro and small cell eNBs is proposed. It is demonstrated how proper configuration of the proposed flow control algorithm offers trade-offs between reducing the probability that one of the eNBs involved in the DC runs out of data and limiting the buffering time in the corresponding eNB. Simulation results show that the performance of DC over traditional backhaul connections is close to that achievable with inter-site carrier aggregation (CA) and virtually zero-latency fronthaul connections.
Shear-mode Piezo transducers for HGA dynamics testing (2003)

Shakers used in modern head gimbal assembly (HGA) resonance testers need to be linear, repeatable, and with minimal out-of-plane movements up to several tens of kilohertz. The authors investigate the suitability of shear-mode piezo actuators for the task. These compact devices also double up as sensors for HGA dynamics testing.
Correlation between surface morphology and breakdown characteristics of thermally grown SiO<inf>2</inf> dielectrics in 4H-SiC MOS devices (2011)

We have investigated the surface and interface morphology of a thermally grown SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> /4H-SiC(0001) structure by atomic force microscopy and transmission electron microscopy. It was found that the surface roughness results in thickness fluctuation of thermal SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sub> due to the pronounced oxidation near the steps. Thus, the localized high elevated electric field near the steps accelerates dielectric degradation and hence results in poor gate oxide reliability.
A chase-game to teach children on a robot to follow moving objects (2014)

Due to lack of mobility, children are limited in their interaction with others. This lack of interaction with peers leads to emotional problems in children with special needs, behavior disorders, and social maladjustment. These social problems continue even when these children become adults. Hence, it is important to promote social skills at a very early age. In this study, we suggest a new training paradigm for young infants and toddlers seated on mobile robots, using force feedback joystick, to bring them closer to their peers so that it can facilitate interaction. Four healthy children participated in a game as they chase a caregiver. A haptic force feedback strategy teaches how to follow the caregiver. The force feedback guidance strategy is tested as a training tool to bring the children in close proximity to their peers.
Performance analysis of cognitive AF relay networks with multiuser switched diversity in Rayleigh fading channels (2017)

The multiuser switched diversity (MUSwiD) selection schemes are useful in reducing the required channel estimation load in wireless networks. In this paper, we propose and evaluate the performance of cognitive amplify-and-forward (AF) MUSwiD relay networks where a cognitive user is selected among a set of users for data reception. The selection process is performed such that the end-to-end (e2e) signal-to-noise ratio (SNR) of the selected user satisfies a predetermined switching threshold. Such a user that satisfies this threshold is scheduled instead of the best user to receive its message from the secondary source. In the proposed system, we consider a cognitive source, a cognitive relay, a set of cognitive users, and a primary user. In this paper, an upper bound on the e2e SNR of a user is used in deriving of closed-form approximations for the outage probability and average symbol error probability (ASEP) of the studied system in addition to deriving the ergodic channel capacity. To get more about system insights, the performance is studied at the high SNR regime where approximate expressions for the outage probability, SEP, diversity order, and coding gain are derived. The derived analytical and asymptotic expressions are verified by Monte-Carlo simulations, and some numerical examples are provided to illustrate the effect of some parameters such as number of users and switching threshold on the system performance. Findings illustrate that the diversity order of the studied cognitive AF multiuser switched diversity relaying network is the same as its non-cognitive counterpart. Also, results show that the asymptotic results tightly converge to the exact ones, and the analytical bounds are indeed very tight, validating the accuracy of our approach of analysis. Furthermore, findings illustrate that the proposed MUSwiD user selection schemes are efficient in the range of low SNR values, which makes them attractive options for practical implementation in emerging mobile broadband communication systems. In contrast, these selection schemes are shown to be inefficient in the range of high SNR values where the multiuser diversity gain is noticeably degraded when they are implemented.
IMA901 Multipeptide Vaccine Randomized International Phase III Trial (IMPRINT): A randomized, controlled study investigating IMA901 multipeptide cancer vaccine in patients receiving sunitinib as first-line therapy for advanced/metastatic RCC. (2011)

TPS183 Background: IMA901 is a therapeutic vaccine composed of multiple naturally presented tumor-associated peptides (TUMAPs). Previous data have indicated that vaccination with IMA901 results in a relevant clinical benefit, ie. advanced RCC patients with detectable T cell responses against TUMAPs had a better disease control and overall survival as compared to patients without such responses. Furthermore, pre-treatment with a single dose of cyclophosphamide (CY; 300mg/m2) was able to reduce regulatory T cells (Treg) and improve survival compared to patients vaccinated without prior CY, resulting in considerably longer median survival than expected (>24 months in second-line cytokine pre-treated mRCC patients). Treatment with IMA901 was overall well tolerated with most AE being local side effects. Suntinib is a standard treatment for mRCC and was approved based on the improvement of PFS. It has been speculated that sunitinib may also favorably alter immune regulation via reduction of Treg and myeloid-derived suppressor cells (MDSC). Various pre-clinical and clinical data have suggested that the combination of sunitinib and therapeutic vaccines is feasible, safe, and potentially synergistic. Methods: This is a randomized phase III study to investigate whether IMA901, when administered in addition to sunitinib, can prolong overall survival (OS; primary endpoint). Secondary endpoints include a subgroup analysis of OS in patients positive for a pre-defined biomarker signature, PFS, best overall objective response, immunomonitoring, and safety. Approximately 330 patients will be randomized to receive sunitinib or sunitinib plus IMA901 (total of 10 i.d. vaccinations together with 75 µg GM-CSF starting in the first “off-phase” and preceeded by a single low-dose CY). Main inclusion criteria comprise advanced/metastatic clear cell RCC without prior systemic therapy for advanced disease, HLA-A*02 expression, favorable or intermediate risk according to Heng. Screening has started in December 2010 and first data are expected by the second half of 2013.
Community-Level Waterbird Responses to Water Hyacinth (Eichhornia crassipes) (2012)

Water hyacinth is among the most widespread invasive plants worldwide; however, its effects on waterbirds are largely undocumented. We monitored site use by waterbirds at Lake Chapala, the largest lake in Mexico and recently designated Ramsar site, to evaluate the potential influence of water hyacinth cover on species composition and aggregate measures of the waterbird community, including waterbird density, species richness, and Simpson's index of diversity. We examined the response of waterbirds to changes in percent water hyacinth cover at 22 independent sites around the lake during six study seasons from May 2006 to February 2008. We found little evidence to suggest that percent water hyacinth cover affected aggregate community measures; however, multivariate analysis of relative species composition suggested that water hyacinth cover corresponded with seasonal species composition (Canonical Correspondence r = 0.66, P = 0.007) when seasonal site cover averaged 17.7 ± 4.67% (winter 2007). Several migratory species were not observed during this season, which could suggest that some small-bodied migratory species avoided Lake Chapala during the winter of high water hyacinth cover. We suspect that observed changes in the waterbird community are in response to species-specific tolerances for water hyacinth and indirect abiotic and biotic effects of its presence (e.g., invertebrate and fish composition).