gebhart/patrepeval huggingface dataset:
The Combustion System Emitting Only Pure Carbon Dioxide by Using Molten Salt's Redox Couples (2005)

The authors proposes an innovative technology “Molten Salt Redox Combustion Energy System”, that includes the flameless combustion in molten salt. This system generates a high temperature without dis-charging pollutants coming from combustion of fuels. At the same time, it is possible to recover the pure carbon dioxide.This system characterized by coupling two redox reactions occurring at different places, separately. At one place, the oxidation of the redox couple by air proceeds, while at the other, the reduction reaction with fuels does.This system is ready for giving the following advantages.·Pure carbon dioxide from the combustion of fuels can be recovered.·Thermal NOx is not generated, because of relatively low temperature reactions.·Sulfur, nitrogen and chlorine compounds in fuels are caught in molten salt as sulfates, nitrates and chlorides of alkali metals.·The mix fuels of a variety of compositions can be applied.·A few kinds of oxidation-reduction couples can provide the chemical heat pump effect.As the first step of developing this combustion system, the authors describe the theoretical concept and discusses it feasibility based on the chemical thermodynamics. The promising redox couples were found successfully.
Second-Order Balanced Truncation for Passive-Order Reduction of RLCK Circuits (2008)

In this paper, we propose a novel model-order reduction (MOR) approach, second-order balanced truncation (BT) for passive-order reduction (SBPOR), which is the first second-order BT method proposed for passive reduction of RLCK circuits. By exploiting the special structure information in the circuit formulation, second-order Gramians are defined based on a symmetric first-order realization in descriptor from. As a result, SBPOR can perform the traditional balancing with passivity-preserving congruency transformation at the cost of solving one generalized Lyapunov equation. Owing to the second-order formulation, SBPOR also preserves the structure information inherent to RLCK circuits. We further propose, second-order Gramian approximation (SOGA) version of SBPOR , to mitigate high computational cost of solving Lyapunov equation. Experimental results demonstrate that SBPOR and SOGA are globally more accurate than the Krylov subspace based approaches.
Sorption and transport of CO 2 above and below the glass transition of poly(ethylene terephthalate) (1980)

Abstract At temperatures at least 30°C above the glass transition ( T g ) the sorption and transport of carbon dioxide in poly(ethylene terephthalate) (PET) can be described conveniently using Henry's law and Fick's law with a constant diffusion coefficient. Below T g Fick's law with a concentration‐ dependent diffusion coefficient, coupled with a sorption isotherm which is concave toward the pressure axis adequately describes the observed sorption and transport data. Physical interpretations of the quantitative deviations from Henry's law and the form of the concentration dependence of the diffusion coefficient is provided by a model which hypothesizes dual modes of sorption and separate non zero mobilities of two populations of sorbed species in local equilibrium. The implications of the observed temperature variations of the phenomenological model parameters are discussed. Dilatometric parameters for PET, polycarbonate, and poly(acrylonitrile) (PAN) are shown to correlate well with a simple. relationship developed to explain the existence of the “extra” mode of sorption responsible for deviations from Henry's law for CO in glassy polymers. In the temperature range from T g to + 20°C, deviations from Fickian behavior are also apparent. These effects are consistent with a transition in the nature of the polymer from an elastic solid below T g to a viscous liquid above T g In the narrow temperature range slightly above T the time scale for chain rearrangements apparently approaches that for the diffusion process. The polymer's viscoelastic response to the probing molecule, therefore, causes deviations from the classical time lag predictions. These deviations disappear 30°C above T g .
Highly Selective Copper-Catalyzed Ring Expansion of Vinyl Thiiranes:  Application to Synthesis of Biotin and the Heterocyclic Core of Plavix (2007)

We report herein a new, highly selective, mild copper-catalyzed vinyl thiirane ring-expansion protocol for the formation of 2,5-dihydrothiophenes. Preliminary substrate scope and applications of this new synthetic disconnection to the formal racemic total synthesis of biotin and the synthesis of the antiplatelet blockbuster pharmaceutical agent Plavix are described.
Handheld underwater 3D sensor based on fringe projection technique (2015)

A new, handheld 3D surface scanner was developed especially for underwater use until a diving depth of about 40 meters. Additionally, the sensor is suitable for the outdoor use under bad weather circumstance like splashing water, wind, and bad illumination conditions. The optical components of the sensor are two cameras and one projector. The measurement field is about 250 mm x 200 mm. The depth resolution is about 50 μm and the lateral resolution is approximately 150 μm. The weight of the scanner is about 10 kg. The housing was produced of synthetic powder using a 3D printing technique. The measurement time for one scan is between a third and a half second. The computer for measurement control and data analysis is already integrated into the housing of the scanner. A display on the backside presents the results of each measurement graphically for a real-time evaluation of the user during the recording of the measurement data.
SDN-Enabled Sliceable BVT Based on Multicarrier Technology for Multiflow Rate/Distance and Grid Adaptation (2015)

We propose a sliceable bandwidth variable transceiver (S-BVT) architecture suitable for metro/regional elastic networks and highly scalable data center applications. It adopts multicarrier modulation, either OFDM or DMT, and a cost-effective optoelectronic front-end. The high-capacity S-BVT is programmable, adaptive, and reconfigurable by an SDN controller for efficient resource usage, enabling unique granularity, flexibility, and grid adaptation, even in the conventional fixed-grid networks. We experimentally demonstrate its multiple advanced functionalities in a four-node photonic mesh network. This includes SDN-enabled rate/distance adaptive multiflow generation and routing/switching, slice-ability, flexibility, and adaptability for the mitigation of spectrum fragmentation, as well as for a soft migration toward the flexi-grid paradigm.
Neuronal uptake affects dynamic characteristics of heart rate response to sympathetic stimulation (1999)

Recently, studies in our laboratory involving the use of a Gaussian white noise technique demonstrated that the transfer function from sympathetic stimulation frequency to heart rate (HR) response showed dynamic characteristics of a second-order low-pass filter. However, determinants for the characteristics remain to be established. We examined the effect of an increase in mean sympathetic stimulation frequency and that of a blockade of the neuronal uptake mechanism on the transfer function in anesthetized rabbits. We found that increasing mean sympathetic stimulation frequency from 1 to 4 Hz significantly (P < 0.01) decreased the dynamic gain of the transfer function without affecting other parameters, such as the natural frequency, lag time, or damping coefficient. In contrast, the administration of desipramine (0.3 mg/kg iv), a neuronal uptake blocking agent, significantly (P < 0.01) decreased both the dynamic gain and the natural frequency and prolonged the lag time. These results suggest that the removal rate of norepinephrine at the neuroeffector junction, rather than the amount of available norepinephrine, plays an important role in determining the low-pass filter characteristics of the HR response to sympathetic stimulation.
Active Control of Inertial Focusing Positions and Particle Separations Enabled by Velocity Profile Tuning with Coflow Systems (2018)

Inertial microfluidics has drawn much attention not only for its diverse applications but also for counterintuitive new fluid dynamic behaviors. Inertial focusing positions are determined by two lift forces, that is, shear gradient and wall-induced lift forces, that are generally known to be opposite in direction in the flow through a channel. However, the direction of shear gradient lift force can be reversed if velocity profiles are shaped properly. We used coflows of two liquids with different viscosities to produce complex velocity profiles that lead to inflection point focusing and alteration of inertial focusing positions; the number and the locations of focusing positions could be actively controlled by tuning flow rates and viscosities of the liquids. Interestingly, 3-inlet coflow systems showed focusing mode switching between inflection point focusing and channel face focusing depending on Reynolds number and particle size. The focusing mode switching occurred at a specific size threshold, which was easily adjustable with the viscosity ratio of the coflows. This property led to different-sized particles focusing at completely different focusing positions and resulted in highly efficient particle separation of which the separation threshold was tunable. Passive separation techniques, including inertial microfluidics, generally have a limitation in the control of separation parameters. Coflow systems can provide a simple and versatile platform for active tuning of velocity profiles and subsequent inertial focusing characteristics, which was demonstrated by active control of the focusing mode using viscosity ratio tuning and temperature changes of the coflows.
Supplementary Figure S7 from Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance (2023)

&lt;p&gt;Supplementary Figure S7. Live-cell immunostaining shows relatively minor changes in ADAM10 and ADAM17 surface levels following MEKi. Measurements were taken 1, 2, and 3h following inhibitor treatment and averaged (*p=0.02, n=3).&lt;/p&gt;
Augmented bricklaying (2020)

Abstract Augmented bricklaying explores the manual construction of intricate brickwork through visual augmentation, and applies and validates the concept in a real-scale building project—a fair-faced brickwork facade for a winery in Greece. As shown in previous research, robotic systems have proven to be very suitable to achieve various differentiated brickwork designs with high efficiency but show certain limitations, for example, in regard to spatial freedom or the usage of mortar on site. Hence, this research aims to show that through the use of a craft-specific augmented reality system, the same geometric complexity and precision seen in robotic fabrication can be achieved with an augmented manual process. Towards this aim, a custom-built augmented reality system for in situ construction was established. This process allows bricklayers to not depend on physical templates, and it enables enhanced spatial freedom, preserving and capitalizing on the bricklayer’s craft of mortar handling. In extension to conventional holographic representations seen in current augmented reality fabrication processes that have limited context-awareness and insufficient geometric feedback capabilities, this system is based on an object-based visual–inertial tracking method to achieve dynamic optical guidance for bricklayers with real-time tracking and highly precise 3D registration features in on-site conditions. By integrating findings from the field of human–computer interfaces and human–machine communication, this research establishes, explores, and validates a human–computer interactive fabrication system, in which explicit machine operations and implicit craftsmanship knowledge are combined. In addition to the overall concept, the method of implementation, and the description of the project application, this paper also quantifies process parameters of the applied augmented reality assembly method concerning building accuracy and assembly speed. In the outlook, this paper aims to outline future directions and potential application areas of object-aware augmented reality systems and their implications for architecture and digital fabrication.
Gas Sensing with Hollow Core Fiber for Leak Detection and Localization (2016)

A gas sensor to detect and localize leaks is being developed. Periodically perforated hollow core fiber and tunable diode laser spectroscopy in the mid-IR can provide robust ppm sensitivity with distributed detection for many gases.
Searching for Novel Cdk5 Substrates in Brain by Comparative Phosphoproteomics of Wild Type and Cdk5−/− Mice (2014)

Protein phosphorylation is the most common post-translational modification that regulates several pivotal functions in cells. Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase which is mostly active in the nervous system. It regulates several biological processes such as neuronal migration, cytoskeletal dynamics, axonal guidance and synaptic plasticity among others. In search for novel substrates of Cdk5 in the brain we performed quantitative phosphoproteomics analysis, isolating phosphoproteins from whole brain derived from E18.5 Cdk5+/+ and Cdk5-/- embryos, using an Immobilized Metal-Ion Affinity Chromatography (IMAC), which specifically binds to phosphorylated proteins. The isolated phosphoproteins were eluted and isotopically labeled for relative and absolute quantitation (iTRAQ) and mass spectrometry identification. We found 40 proteins that showed decreased phosphorylation at Cdk5-/- brains. In addition, out of these 40 hypophosphorylated proteins we characterized two proteins, :MARCKS (Myristoylated Alanine-Rich protein Kinase C substrate) and Grin1 (G protein regulated inducer of neurite outgrowth 1). MARCKS is known to be phosphorylated by Cdk5 in chick neural cells while Grin1 has not been reported to be phosphorylated by Cdk5. When these proteins were overexpressed in N2A neuroblastoma cell line along with p35, serine phosphorylation in their Cdk5 motifs was found to be increased. In contrast, treatments with roscovitine, the Cdk5 inhibitor, resulted in an opposite effect on serine phosphorylation in N2A cells and primary hippocampal neurons transfected with MARCKS. In summary, the results presented here identify Grin 1 as novel Cdk5 substrate and confirm previously identified MARCKS as a a bona fide Cdk5 substrate.
Quantification and Dosing of Renal Replacement Therapy in Acute Kidney Injury: A Reappraisal (2017)

We propose an adaptation of a maintenance dialysis parameter (standard Kt/V) as a benchmark to supplement effluent-based dosing of CRRT. Video Journal Club "Cappuccino with Claudio Ronco" at http://www.karger.com/?doi=475457.
Supplementary Table 1 from GROα Is Highly Expressed in Adenocarcinoma of the Colon and Down-Regulates Fibulin-1 (2023)

Supplementary Table 1 from GROα Is Highly Expressed in Adenocarcinoma of the Colon and Down-Regulates Fibulin-1
<title>Visual feature discrimination versus compression ratio for polygonal shape descriptors</title> (2000)

In the last decade several methods for low level indexing of visual features appeared. Most often these were evaluated with respect to their discrimination power using measures like precision and recall. Accordingly, the targeted application was indexing of visual data within databases. During the standardization process of MPEG-7 the view on indexing of visual data changed, taking also communication aspects into account where coding efficiency is important. Even if the descriptors used for indexing are small compared to the size of images, it is recognized that there can be several descriptors linked to an image, characterizing different features and regions. Beside the importance of a small memory footprint for the transmission of the descriptor and the memory footprint in a database, eventually the search and filtering can be sped up by reducing the dimensionality of the descriptor if the metric of the matching can be adjusted. Based on a polygon shape descriptor presented for MPEG-7 this paper compares the discrimination power versus memory consumption of the descriptor. Different methods based on quantization are presented and their effect on the retrieval performance are measured. Finally an optimized computation of the descriptor is presented.
Mutational analysis of the mRNA operator for T4 DNA polymerase. (1991)

Biosynthesis of bacteriophage T4 DNA polymerase is autogenously regulated at the translational level. The enzyme, product of gene 43, represses its own translation by binding to its mRNA 5' to the initiator AUG at a 36-40 nucleotide segment that includes the Shine-Dalgarno sequence and a putative RNA hairpin structure consisting of a 5-base-pair stem and an 8-base loop. We constructed mutations that either disrupted the stem or altered specific loop residues of the hairpin and found that many of these mutations, including single-base changes in the loop sequence, diminished binding of purified T4 DNA polymerase to its RNA in vitro (as measured by a gel retardation assay) and derepressed synthesis of the enzyme in vivo (as measured in T4 infections and by recombinant-plasmid-mediated expression). In vitro effects, however, were not always congruent with in vivo effects. For example, stem pairing with a sequence other than wild-type resulted in normal protein binding in vitro but derepression of protein synthesis in vivo. Similarly, a C----A change in the loop had a small effect in vitro and a strong effect in vivo. In contrast, an A----U change near the base of the hairpin that was predicted to increase the length of the base-paired stem had small effects both in vitro and in vivo. The results suggest that interaction of T4 DNA polymerase with its structured RNA operator depends on the spatial arrangement of specific nucleotide residues and is subject to modulation in vivo.
Detecting Glaucoma in the Ocular Hypertension Treatment Study Using Deep Learning: Implications for clinical trial endpoints (2021)

&lt;p&gt;&lt;/p&gt;&lt;p&gt;To investigate the diagnostic accuracy of deep learning (DL) algorithms to detect primary open-angle glaucoma (POAG) trained on fundus photographs from the Ocular Hypertension Treatment Study (OHTS). 66,715 photographs from 3,272 eyes were used to train and test a ResNet-50 model to detect the OHTS Endpoint Committee POAG determination based on optic disc (n=287 eyes, 3,502 photographs) and/or visual field (n=198 eyes, 2,300 visual fields) changes. OHTS training, validation and testing sets were randomly determined using an 85-5-10 percentage split by subject. Three independent test sets were used to estimate the generalizability of the model: UCSD Diagnostic Innovations in Glaucoma Study (DIGS, USA), ACRIMA (Spain) and Large-scale Attention-based Glaucoma (LAG, China). The DL model achieved an AUROC (95% CI) of 0.88 (0.82, 0.92) for the overall OHTS POAG endpoint. For the OHTS endpoints based on optic disc changes or visual field changes, AUROCs were 0.91 (0.88, 0.94) and 0.86 (0.76, 0.93), respectively. False-positive rates (at 90% specificity) were higher in photographs of eyes that later developed POAG by disc or visual field (19.1%) compared to eyes that did not develop POAG (7.3%) during their OHTS follow-up. The diagnostic accuracy of the DL model developed on the OHTS optic disc endpoint applied to 3 independent datasets was lower with AUROC ranging from 0.74 to 0.79. High diagnostic accuracy of the current model suggests that DL can be used to automate the determination of POAG for clinical trials and management. In addition, the higher false-positive rate in early photographs of eyes that later developed POAG suggests that DL models detected POAG in some eyes earlier than the OHTS Endpoint Committee.&lt;/p&gt;
Localization of Broca's Area Using Functional MR Imaging: Quantitative Evaluation of Paradigms (2009)

Word generation versus fixation could effectively and reliably delineate the frontal language area. A customized effective paradigm should be analyzed in order to evaluate various language functions.
High-flow nasal cannula for COVID-19 patients: risk of bio-aerosol dispersion (2020)

International audience
Rapid synthesis of unsaturated alcohols under mild conditions by highly selective hydrogenation (2013)

Ir-ReOx/SiO2 acted as a highly active and selective heterogeneous catalyst for the hydrogenation of unsaturated aldehydes to unsaturated alcohols in water at low H2 pressure (0.8 MPa) and low temperature (303 K). The catalysis is derived from the synergy between Ir metal and ReOx.
Identification of the rat homologue ofKAI1 and its expression in dunning rat prostate cancers (1998)

These studies demonstrated that downregulation of the 2.0-kb KAI1 mRNA is associated with the acquisition of high metastatic ability by prostate cancer cells.
Manipulating the conformation and interplay of p-sulfonated calix[4]arenes by lower rim tri-substitution with N′-cyanocarbamimidate groups (2014)

<italic>p</italic>-Sulfonatocalix[4]arenes with three of the lower rim hydroxyl groups substituted with <italic>N</italic>′-cyanocarbamimidate groups crystallizes in the 1,3-alternate conformation rather than the common cone conformation for unsubstituted calixarenes, with departure from a bilayer arrangement.
A Hardware Prototype for Joint Radar-Communication System Using Spatial Modulation (2021)

Dual-function radar and communications (DFRC) systems implement radar and communications on the same platform, which lead to substantial gains in performances as well as the system cost, weight, and power consumption. Recently, a spatial modulation based communication radar (SpaCoR) system, which has improved data rates and radar angular resolution compared with the techniques using fixed antenna allocation, was proposed to facilitate the co-existence of both functionalities on the same platform. In this paper, we implement a prototype with dedicated hardware and software components to verify the feasibility of SpaCoR. In addition to realizing SpaCoR, this prototype can be utilized to demonstrate a multitude of DFRC systems as it consists of multiple modules including baseband waveform generation, over-the-air signaling, frequency band waveform transmission, radar echo generation, radar echo reception, and communication signal reception. We evaluate SpaCoR using actual passband waveforms with over-the-air signaling. The results show that the communications subsystem of SpaCoR achieves improved bit error rate (BER) performance compared to the fixed allocation system when using the same data rate. For the radar subsystem, the experiments show that spatial agility of SpaCoR leads to improved angular resolution.
Dcas Supports Cell Polarization and Cell-Cell Adhesion Complexes in Development (2010)

Mammalian Cas proteins regulate cell migration, division and survival, and are often deregulated in cancer. However, the presence of four paralogous Cas family members in mammals (BCAR1/p130Cas, EFS/Sin1, NEDD9/HEF1/Cas-L, and CASS4/HEPL) has limited their analysis in development. We deleted the single Drosophila Cas gene, Dcas, to probe the developmental function of Dcas. Loss of Dcas had limited effect on embryonal development. However, we found that Dcas is an important modulator of the severity of the developmental phenotypes of mutations affecting integrins (If and mew) and their downstream effectors Fak56D or Src42A. Strikingly, embryonic lethal Fak56D-Dcas double mutant embryos had extensive cell polarity defects, including mislocalization and reduced expression of E-cadherin. Further genetic analysis established that loss of Dcas modified the embryonal lethal phenotypes of embryos with mutations in E-cadherin (Shg) or its signaling partners p120- and beta-catenin (Arm). These results support an important role for Cas proteins in cell-cell adhesion signaling in development.