gebhart/patrepeval huggingface dataset:
Response of the central metabolism ofCorynebacterium glutamicum to different flux burdens (1997)

To evaluate the importance of reactions within the central metabolism under different flux burdens the fluxes within the pentose phosphate pathway (PPP), as well as the other reactions of the central metabolism, were intensively analyzed and quantitated. For this purpose, Corynebacterium glutamicum was grown with [1-(13)C]glucose to metabolic and isotopic steady state and the fractional enrichments in precursor metabolites (e.g., pentose 5-phosphate) were quantified. Matrix calculus was used to express these data together with metabolite mass data. The detailed analysis of the dependence of (13)C enrichments on exchange fluxes enabled the transketolase-catalyzed exchange rate (2 pentose 5-phosphate <--> sedoheptulose 7-phosphate + glyceraldehyde 3-phosphate) to be quantified as 74.3% (molar metabolite flux) at a net flux of 10.3% and the exchange rate (pentose 5-phosphate + erythrose 4-phosphate <--> fructose 6-phosphate + glyceraldehyde 3-phosphate) to be quantified as 5.6% at a net flux of 8.1%. The flux entering the tricarboxylic acid cycle was 93.3%. The same comprehensive flux analysis as performed for the nonexcreting condition was done with the identical strain that had been forced to excrete L-glutamate. Because we had already quantified the fluxes for L-lysine excretion with an isogenic strain, three directly comparable flux situations are thus available. Consequently, this comparison permits a direct cause-and-effect relationship to be specified. In response to the different flux burdens of the cell, the PPP flux decreased from a maximum of 67% to 26%, with the glycolytic flux increasing accordingly. The carbon flux through isocitrate dehydrogenase increased from 20% to 36%. The bidirectional carbon flux between pyruvate and oxaloacetate decreased from 36% to 9%. Since the cause of the three different flux states was the allelic exchange in the final L-lysine assembling pathway or the glutamate export activity, respectively, the flexible response is the effect. This shows conclusively the enormous flexibility within the central metabolism of C. glutamicum to supply precursors upon their withdrawal for the synthesis of amino acids. (c) 1997 John Wiley & Sons, Inc. Biotechnol Bioeng 56: 168-180, 1997.
Simple Multiplexing Hand-Held Control Unit (1989)

Multiplexer consists of series of resistors, each shunted by single-pole, single-throw switch. User operates switches by pressing buttons or squeezing triggers. Prototype includes three switches operated successfully in over 200 hours of system operations. Number of switches accommodated determined by signal-to-noise ratio of current source, noise induced in control unit and cable, and number of bits in output of analog-to-digital converter. Because many computer-contolled robots have extra analog-to-digital channels, such multiplexer added at little extra cost.
Variation Analysis of CMOS Technologies Using Surface-Potential MOSFET Model (2009)

An analysis of the measured macroscopic withinwafer variations for threshold voltage (Vth) and on-current (Ion) over several technology generations (180 nm, 100 nm and 65 nm) is reported. It is verified that the dominant microscopic variations of the MOSFET device can be extracted quantitatively from these macroscopic variation data by applying the surface-potential compact model Hiroshima University STARC IGFET model 2 (HiSIM2), which is presently brought into industrial application. Only a small number of microscopic parameters, representing substrate doping (NSUBC), pocket-implantation doping (NSUBP), carrier-mobility degradation due to gate-interface roughness (MUESR1) and channel-length variation during the gate formation (XLD) are found sufficient to quantitatively reproduce the measured macroscopic within-wafer variations of Vth and Ion for all channel length Lg and all technology generations. Quantitative improvements from 180 nm to 65 nm are confirmed to be quite large for MUESR1 (about 70%) and Lmin(XLD) (55%) variations, related to the gate-oxide interface and the gate-stack structuring, respectively. On the other hand, doping-related technology advances, which are reflected by the variation magnitudes of NSUBC (30%) and NSUBP (25%), are found to be considerably smaller. Furthermore, specific combinations of extreme microscopic parameter-variation values are able to represent the boundaries of macroscopic fabrication inaccuracies for Vth and Ion. These combinations are found to remain identical, not only for all Lg of a given technology node, but also for all investigated technologies with minimum Lg of 180 nm, 100 nm and 65 nm.
Determining shape and reflectance of Lambertian, specular, and hybrid surfaces using extended sources (2003)

A method is presented for determining the shape of surfaces whose reflectance properties can vary from Lambertian to specular, without prior knowledge of the relative strengths of the Lambertian and specular components of reflection. The object surface is illuminated using extended light sources and is viewed from a single direction. Surface illumination using extended sources makes it possible to ensure the detection of both Lambertian and specular reflections. Multiple source directions are used to obtain an image sequence of the object. An extraction algorithm uses the set of image intensity values measured at each surface point to compute orientation as well as relative strengths of the Lambertian and specular reflection components. The method, photometric sampling, uses samples of a photometric function that relates image intensity to surface orientation, reflectance, and light source characteristics. Experiments conducted on Lambertian surfaces, specular surfaces, and hybrid surfaces show high accuracy in measured orientations and estimated reflectance parameters.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Reconsidering algorithms for iterative solvers in the multicore era (2009)

Efficient solution of computational problems require a match between the algorithm and the underlying architecture. New multicore processors feature low intra-chip communication cost and smaller per-thread caches compared to single-core implementations, indicating that data locality issues are more important than communication overheads. We investigate the impact of these changes on parallel multigrid methods. We present a temporally blocked, naturally ordered, smoother implementation that improves the data locality as much as ten times compared with the standard red-black algorithm. We present results of the performance of our new algorithm on an SMP system, an UltraSPARC T1 (Niagara) SMT/CMP, and a simulated CMP processor.
Comparing Published Scientific Journal Articles to Their Pre-print Versions (2016)

Academic publishers claim that they add value to scholarly communications by coordinating reviews and contributing and enhancing text during publication. These contributions come at a considerable cost: U.S. academic libraries paid $1.7 billion for serial subscriptions in 2008 alone. Library budgets, in contrast, are flat and not able to keep pace with serial price inflation. We have investigated the publishers' value proposition by conducting a comparative study of pre-print papers and their final published counterparts. This comparison had two working assumptions: 1) if the publishers' argument is valid, the text of a pre-print paper should vary measurably from its corresponding final published version, and 2) by applying standard similarity measures, we should be able to detect and quantify such differences. Our analysis revealed that the text contents of the scientific papers generally changed very little from their pre-print to final published versions. These findings contribute empirical indicators to discussions of the added value of commercial publishers and therefore should influence libraries' economic decisions regarding access to scholarly publications.
Adaptive storage control for page frame supply in large scale computer systems (1988)

A real storage management algorithm called Adaptive Control of Page-frame Supply (ACPS) is described. ACPS employees three strategies: prediction of the demand for real page frames, page replacement based on the prediction, and working set control. Together, these strategies constitute the real page frame allocation method, and contribute to short and stable response times in conversational processing environments. ACPS is experimentally applied to the VOS3 operating system. Evaluation of ACPS on a real machine shows that TSS response times are not affected too strongly by king-size jobs and ACPS is successful in avoiding paging delay and thrashing. ACPS prevents extreme shortages of real storage in almost all cases.
Glass patterns as moiré effects: new surprising results (2003)

It is well known that the superposition of two identical random dot patterns may give rise to a particular form of moiré effect known as a Glass pattern. Surprisingly, new research results show that if one chooses appropriate dot shapes for each of the two random dot patterns, while keeping the random dot locations in both layers identical, it is possible to synthesize in the superposition a Glass pattern having any desired shape and intensity profile.
Hand External Force Estimation Method for 5-Axes Scott-Russell Robot Arm (2018)

It is necessary to adapt the force control to the robot, in order to make robots perform complex tasks as human beings. In force control, the external force is measured by a force sensor attached to the tip of the robot arm. However, there are problems such as cost and labor of installation time. Therefore, the purpose of this study is to construct the method to estimate the force applied to the hand without using the sensor based on the dynamic model. In order to construct the dynamics model, modeling of this robot arm, constructing equation of motion and friction torque identification were performed. After that, an external force estimation experiment was performed and verified the effectiveness of this method was shown.
Dodging Drug-Resistant Cancer with Diamonds (2011)

Nanodiamond-drug conjugates show antitumor activity in mouse models of chemoresistant breast and liver cancer.
A Fundamental Hedge (2012)

The Standard & Poor's Diversified Trends Indicator (S&P DTI) and the Long/Short Methodology (LSM) are a fundamental hedge to stocks. However, they are not structured to be a direct monthly hedge to falling equity or bond prices; therefore, one should not expect them to display negative correlation to either market. The critical aspect of the relationship between the S&P 500 and the LSM/S&P DTI, and the fundamental nature of the hedge, is depicted by time in the various results table. The Long/Short Methodology (LSM) is a proxy for the S&P DTI. From 1961 to 1984, one used a basket of futures in the LSM compared to that used in the S&P DTI. A big-four accounting firm has attested to the S&P DTI from 1985 to May 2001 for a major brokerage firm.
Tuning of the Acoustic Boundary Conditions of Combustion Test Rigs With Active Control: Extension to Actuators With Nonlinear Response (2010)

In the design process, new burners are generally tested in combustion test rigs. With these experiments, as well as with computational fluid dynamics, finite element calculations, and low-order network models, the burner’s performance in the full-scale engine is sought to be predicted. Especially, information about the thermoacoustic behavior and the emissions is very important. As the thermoacoustics strongly depend on the acoustic boundary conditions of the system, it is obvious that test rig conditions should match or be close to those of the full-scale engine. This is, however, generally not the case. Hence, if the combustion process in the test rig is stable at certain operating conditions, it may show unfavorable dynamics at the same conditions in the engine. In previous works, the authors introduced an active control scheme, which is able to mimic almost arbitrary acoustic boundary conditions. Thus, the test rig properties can be tuned to correspond to those of the full-scale engine. The acoustic boundary conditions were manipulated using woofers. In the present study, an actuator with higher control authority is investigated, which could be used to apply the control scheme in industrial test rigs. The actuator modulates an air mass flow to generate an acoustic excitation. However, in contrast to the woofers, it exhibits a strong nonlinear response regarding amplitude and frequency. Thus, the control scheme is further developed to account for these nonlinear transfer characteristics. This modified control scheme is then applied to change the acoustic boundary conditions of an atmospheric swirl-stabilized combustion test rig. Excellent results were obtained in terms of changing the reflection coefficient to different levels. By manipulating its phase, different resonance frequencies could be imposed without any hardware changes. The nonlinear control approach is not restricted to the actuator used in this study and might therefore be of use for other actuators as well.
Transient reduction of placental angiogenesis in PAI-1-deficient mice (2010)

Murine placentation is associated with the invasion of maternal endometrium by trophoblasts and an extensive maternal and fetal angiogenesis. Plasminogen activator inhibitor-1 (PAI-1) is transiently produced by spongiotrophoblasts and trophoblast giant cells at 10.5-11.5 days postcoitum (dpc). Knowing the key contribution of PAI-1 in the regulation of angiogenesis, we have now analyzed the consequence of PAI-1 deficiency on murine placentation. Morphological and quantitative computer-assisted image analysis revealed abnormal placental morphology in PAI-1-/- mice at 10.5 and 12.5 dpc. At 10.5 dpc, the genetic ablation of PAI-1 resulted in a transient reduction of both maternal and fetal vascularizations in the placenta and increased trophoblast cell density. This was associated with a poorer development of the labyrinth and an extension of the decidua. A larger spongiotrophoblast layer appeared at 12.5 dpc in PAI-1-deficient mice. Placental morphology was normalized at 14.5 dpc. Microarray analyses performed on laser capture microdissected labyrinths revealed that 46 genes were differentially expressed between the two genotypes at 10.5 dpc. However, only 11 genes were still differently modulated at 14.5 dpc, when normalization of placental morphology had taken place. This transcriptomic profiling highlighted a dysregulation in the expression of placenta-related cathepsin family members. Altogether our data provide evidence for a transient impaired placental morphology in PAI-1-deficient mice that is then normalized, leading to normal embryonic development.
Elastic wave propagation in periodic particulate composites with tetragonal particle arrangement (2001)

Transmission of a longitudinal elastic wave through a periodic particulate composite with a tetragonal arrangement of heavy spherical inclusions in an elastic matrix was measured experimentally. It exhibits several band gaps and the associated jumps in the phase velocity spectrum near two sets of frequencies: frequencies at which enhancement of the rigid body (dipole) resonance of a particle through its shear interaction with the remaining particles within the layer; and frequencies determined by the inter-layer distance.
Optimizing structure and function relationship of nucleic acid molecules (1999)

Interactions between two or more molecules are central to all living systems, as they provide the basis for biochemical reactions and regulatory processes. Complex reactions require a precise control in the interaction of the partners and, given the relevance of these interactions, it is of high importance to understand the structural and chemical mechanisms that enable specific molecular recognition.
Nonlinear feedback controller design of a pneumatic muscle actuator system (1999)

A study is conducted on several paradigms to provide closed-loop position control of an actuator powered by a pneumatic muscle system. This actuator has many advantages including having extremely high power/weight and power/volume ratios, being light-weight, autonomous, and safe. An implementation as a tracking controller using a gain scheduling method is presented.
Pressure-Dependent Photon Correlation Spectroscopic Investigation of Poly(propylene oxide) near the Glass Transition (1997)

The effect of pressure on structural relaxations in poly(propylene oxide) (PPO; MW = 4000) near the glass transition has been determined using photon correlation spectroscopy. Experimental results are reported for pressures ranging from 2.5 to 3.9 kbar at 253 K. The structural relaxation exhibits two distinct processes separated by ∼3 orders of magnitude in time. This observation is consistent with results of dielectric relaxation studies of PPO. The faster relaxation is associated with local segmental motions important in the glass−rubber transition. The mean relaxation time for the faster process exhibits an exponential dependence on pressure.
CIS External Review Lightning Presentation: Neuromorphic Graph Algorithms. (2022)

Abstract not provided.
Synthetic Applications of Aliphatic Unsaturated α‐H‐α‐Amino Acids. (2006)

Abstract For Abstract see ChemInform Abstract in Full Text.
Asymmetric focussed arrays for ultrasonic tumor therapy (2002)

This study investigated transducer array configurations to produce thermal necrosis lesions for ultrasonic treatment of ocular tumors. Spherical-cap transducers with segmented strip electrodes were designed to produce asymmetric focal-plane beam patterns that may expedite the production of lesion matrices. Phased electrode excitation was evaluated as a means of reducing focal-point intensities to suppress undesired gas-body formation. Experimental beam patterns agreed well with theoretical results and initial in-vitro experiments demonstrated desired lesion features.
Signs on concrete median barriers. (2013)

Concrete median barriers have been used throughout the state as permanent and temporary barriers for providing separation of traffic. Typically, these barriers are tested and considered crashworthy through crash testing according to National Cooperative Highway Research Program Report 350 or American Association of State Highway and Transportation Officials Manual for Assessment of Safety Hardware. Due to space restrictions, a sign or a light pole is placed on top of such barriers. However, when signs or light poles are mounted on top of barriers, the crashworthiness of the system is not necessarily guaranteed. There is very limited research on how a combination of device and barrier would perform if impacted by an errant vehicle. Moreover, no full-scale crash tests have been performed to accurately identify the influence of attachments on vehicular deceleration. Therefore, there is a need to identify existing practices of placing hardware on top of median barriers, as well as defining the crashworthiness of such combinations. In this project, a survey of the practice of mounting hardware on top of barriers was performed. Analytical, computer simulation, and testing tasks were conducted to define crashworthy hardware and placement guidelines. This research developed a design guideline and a standard that could be incorporated into Texas Department of Transportation standards and specifications.
Ty1 Mobilizes Subtelomeric Y′ Elements in Telomerase-Negative Saccharomyces cerevisiae Survivors (2004)

When telomerase is inactivated in Saccharomyces cerevisiae, telomeric DNA shortens with every cell division, and cells stop dividing after approximately 100 generations. Survivors that form in these senescent populations and resume growing have variably amplified arrays of subtelomeric Y' elements. We marked a chromosomal Y' element with the his3AI retrotransposition indicator gene and found that Y'HIS3 cDNA was incorporated into the genome at approximately 10- to 1,000-fold-higher frequencies in survivors compared to telomerase-positive strains. Y'HIS3 cDNA mobility was significantly reduced if assayed at 30 degrees C, a nonpermissive temperature for Ty1 retrotransposition, or in the absence of Tec1p, a transcription factor for Ty1. Microarray analysis revealed that Y' RNA is preferentially associated with Ty1 virus-like particles (VLPs). Genomic copies of Y'HIS3 cDNA typically have downstream oligo(A) tracts, followed by a complete Ty1 long terminal repeat and TYA1 or TYB1 sequences. These data are consistent with the use of Ty1 cDNA to prime reverse transcription of polyadenylated Y' RNA within Ty1 VLPs. Unmarked Y'-oligo(A)-Ty1 cDNA was also detected in survivors, reaching copy numbers of approximately 10(-2) per genome. We propose that Y'-oligo(A)-Ty1 cDNA recombines with Y' elements at eroding telomeres in survivors and may play a role in telomere maintenance in the absence of telomerase.
Array of Two UV-Wavelength Detector Types (2010)

An approach to fabricate a set of simultaneously operating dual-UV-wavelength detectors is described. The fabrication flow relies on the confined-epitaxy growth method. The confined epitaxial Al <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> Ga <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">1-x</sub> N-layer stacking approach is used to establish simultaneous multiple UV-wavelength detection. The chosen stoichiometries of specific epitaxial layers set the wavelength sensitivity at approximately 355 nm for pixel A and 320 nm for pixel B. Spectral responsivity plots of the detectors clearly show the dual-UV-color sensitivity of the pair. The detectors have signal-to-noise ratios of 15 and 17 and spectral responsivity values of 0.12 AAV and 0.05 AAV for pixel A and pixel B, respectively.
Piezoelectric strain induced variation of the magnetic anisotropy in a high Curie temperature (Ga,Mn)As sample (2012)

We show that effective electrical control of the magnetic properties in the ferromagnetic semiconductor (Ga,Mn)As is possible using the strain induced by a piezoelectric actuator even in the limit of high doping levels and high Curie temperatures, where direct electric gating is not possible. We demonstrate very large and reversible rotations of the magnetic easy axis. We compare the results obtained from magneto-transport and SQUID magnetometry measurements, extracting the dependence of the piezo-induced uniaxial magnetic anisotropy constant upon strain in both cases and detailing the limitations encountered in the latter approach.
Characterization and modelling of Langmuir interfaces with finite elasticity (2017)

A novel neo-Hookean model for compressible, yet elastic interfaces is presented and validated using a radial trough apparatus.
14.3: Distinguished Paper : White Point Calibration of Color Sequential Mobile Projector (2009)

Abstract Color sequential RGB LED driving architecture becomes popular for mobile projectors of which the output are under 10 lumens. One of the difficulties of color sequential projector lies in how to make white balance by mixing RGB color. LED bins and coupling tolerance are diverse so that they have sensitive effects on color temperature distribution. In this paper, the analyses of color temperature distribution and a practical calibration method will be presented.
INTRODUCTION OF MALE STERILITY TO GM CHRYSANTHEMUM PLANTS TO PREVENT TRANSGENE FLOW (2012)

ISHS XXVIII International Horticultural Congress on Science and Horticulture for People (IHC2010): International Symposium on Advances in Ornamentals, Landscape and Urban Horticulture INTRODUCTION OF MALE STERILITY TO GM CHRYSANTHEMUM PLANTS TO PREVENT TRANSGENE FLOW
Model Predictive Control of a Direct Wave Energy Converter Constrained by the Electrical Chain using an Energetic Approach (2015)

International audience