gebhart/patrepeval huggingface dataset:
Searching service repositories by combining semantic and ontological matching (2005)

In this paper, we explore the use of domain-independent and domain-specific ontologies to find matching service descriptions. The domain-independent relationships are derived using an English thesaurus after tokenization and part-of-speech tagging. The domain-specific ontological similarity is derived by an inference on the semantic annotations associated with Web service descriptions. Matches due to the two cues are combined to determine an overall semantic similarity score. By combining multiple cues, we show that better relevancy results can be obtained for service matches from a large repository, than could be obtained using any one cue alone.
Stretched polymer nanohairs by nanodrawing (2007)

We present a simple method for fabricating high aspect-ratio polymer nanostructures on a solid substrate by sequential application of molding and drawing of a thin polymer film. In this method, a thin polymer film is prepared by spin coating on a solid substrate and the temperature is raised above the polymer's glass transition while in conformal contact with a poly(urethane acrylate) (PUA) mold having nano-cavities. Consequently, capillary force induces deformation of the polymer melt into the void spaces of the mold and the filled nanostructure was further elongated upon removal of the mold due to tailored adhesive force at the mold/polymer interface. The optimum value of the work of adhesion at the mold/polymer interface ranged from 0.9 to 1.1 times that at the substrate/polymer interface. Below or above this range, a simple molding or detachment occurred, corresponding to earlier findings.
Surface-Enhanced Raman Spectroelectrochemistry of TTF-Modified Self-Assembled Monolayers (2011)

Surface-enhanced Raman spectroscopy (SERS) was used to monitor the response of a self-assembled monolayer (SAM) of a tetrathiafulvalene (TTF) derivative on a gold film-over-nanosphere electrode. The electrochemical response observed was rationalized in terms of the interactions between TTF moieties as the oxidation state was changed. Electrochemical oxidation to form the monocation caused the absorbance of the TTF unit to coincide with both the laser excitation wavelength and the localized surface plasmon resonance (LSPR), resulting in surface-enhanced resonance Raman scattering (SERRS). The vibrational frequency changes that accompany electron transfer afford a high-contrast mechanism that can be used to determine the oxidation state of the TTF unit in an unambiguous manner.
Predictor-based reference governor for second-order linear constrained systems operated over a communication network (2014)

The paper considers the application of reference governors to enforce state and control constraints in second order closed-loop systems operated remotely over communication networks. The reference governor minimally modifies the reference command to the closed-loop system if this command has a potential to induce constraint violation. Our approach to reference governor design exploits a recently developed fast constraint violation prediction algorithm for second order linear systems, which is extended, in this paper, to handle a time-varying network delay. We also discuss approaches to quantization error handling. A numerical example is reported to illustrate the proposed reference governor implementation.
InGaN-Based Light-Emitting Diodes Fabricated on Nano Patterned Sapphire Substrates with Pillar Height of More than 600 nm by Nanoimprint Lithography (2013)

GaN-based light-emitting diodes (LEDs) were fabricated on nano patterned sapphire substrates (nano-PSSs) by nanoimprint (NIP) lithography. A nano-PSS with a pillar height of more than 600 nm was achieved. The surface emission of the LEDs was strongly affected by pillar height, and the surface emission intensity was highest at a pillar height of 250 nm. In contrast, the external quantum efficiency of the LEDs on the nano-PSSs with diameters of 100 and 450 nm was approximately 30% higher than that on a flat sapphire substrate, which is similar to that on a conventional PSS.
Revisiting a role for a mammary tumor retrovirus in human breast cancer (2013)

There remains great controversy as to whether mouse mammary tumor virus (MMTV), the etiological agent of mammary cancer in mice, or a closely related human retrovirus, plays a role in the development of breast cancer in humans. On one hand, retroviruses such as human T-cell lymphotropic virus and human immunodeficiency virus (HIV) are known causative agents of cancer (in the case of HIV, albeit, indirectly), but attempts to associate other retroviruses with human cancers have been difficult. A recent, high profile, example has been the postulated involvement of another mouse virus, xenotropic murine leukemia virus-related virus, in human prostate cancer, which is now thought to be due to contamination. Here, we review some of the more recent evidence for and against the involvement of MMTV in human breast cancer and suggest future studies that may allow a definitive answer to this conundrum.
The Impact of High-Flow Nasal Cannula Device, Nebulizer Type, and Placement on Trans-Nasal Aerosol Drug Delivery (2021)

During transnasal aerosol delivery, the vibrating mesh nebulizer generated a higher inhaled dose than did the small-volume nebulizer when the nebulizer was placed at the humidifier. With the vibrating mesh nebulizer placed at the humidifier and an HFNC flow > 10 L/min, the inhaled dose was higher than with the vibrating mesh nebulizer placed proximal to the nasal cannula, and the inhaled dose was higher with Optiflow than with Airvo 2.
Supplementary Figure 1 from A First-Generation Multiplex Biomarker Analysis of Urine for the Early Detection of Prostate Cancer (2023)

Supplementary Figure 1 from A First-Generation Multiplex Biomarker Analysis of Urine for the Early Detection of Prostate Cancer
Optical Characterization of Gate Oxide Charging Damage by Photoreflectance Spectroscopy (1999)

Thin gate oxide charging damage induced by plasma exposure in the metal-oxide-semiconductor (MOS) structure has been studied by photoreflectance (PR) spectroscopy. The PR signal intensity around the photon energy of 3.4 eV is found to decrease as the plasma exposure time increases. The capacitance–voltage (C–V) characteristic shows the generation of SiO2/Si interface states as well as that of electron trap sites in the oxides induced by the DC mode Ar plasma exposure. The SiO2/Si interface state plays the role of a recombination center for the photo generated carriers, resulting in the decrease in the surface potential change. On the other hand, the electron trapped in the oxide increases the surface potential. Therefore, the decrement in the PR signal intensity is considered to correspond primarily to the SiO2/Si interface state generation induced by the plasma-process, because the signal intensity decreases with the decrease of the surface potential.
Supplementary Methods, Figure Legends 1-2 from Cancer Cell Dependence on Unsaturated Fatty Acids Implicates Stearoyl-CoA Desaturase as a Target for Cancer Therapy (2023)

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Fighting Ebola with novel spore decontamination technologies for the military (2015)

Recently, global public health organizations such as Doctors without Borders (MSF), the World Health Organization (WHO), Public Health Canada, National Institutes of Health (NIH), and the U.S. government developed and deployed Field Decontamination Kits (FDKs), a novel, lightweight, compact, reusable decontamination technology to sterilize Ebola-contaminated medical devices at remote clinical sites lacking infra-structure in crisis-stricken regions of West Africa (medical waste materials are placed in bags and burned). The basis for effectuating sterilization with FDKs is chlorine dioxide (ClO2) produced from a patented invention developed by researchers at the US Army Natick Soldier RD&E Center (NSRDEC) and commercialized as a dry mixed-chemical for bacterial spore decontamination. In fact, the NSRDEC research scientists developed an ensemble of ClO2 technologies designed for different applications in decontaminating fresh produce; food contact and handling surfaces; personal protective equipment; textiles used in clothing, uniforms, tents, and shelters; graywater recycling; airplanes; surgical instruments; and hard surfaces in latrines, laundries, and deployable medical facilities. These examples demonstrate the far-reaching impact, adaptability, and versatility of these innovative technologies. We present herein the unique attributes of NSRDEC's novel decontamination technologies and a Case Study of the development of FDKs that were deployed in West Africa by international public health organizations to sterilize Ebola-contaminated medical equipment. FDKs use bacterial spores as indicators of sterility. We review the properties and structures of spores and the mechanisms of bacterial spore inactivation by ClO2. We also review mechanisms of bacterial spore inactivation by novel, emerging, and established non-thermal technologies for food preservation, such as high pressure processing, irradiation, cold plasma, and chemical sanitizers, using an array of Bacillus subtilis mutants to probe mechanisms of spore germination and inactivation. We employ techniques of high-resolution atomic force microscopy and phase contrast microscopy to examine the effects of γ-irradiation on bacterial spores of Bacillus anthracis, Bacillus thuringiensis, and Bacillus atrophaeus spp. and of ClO2 on B. subtilis spores, and present in detail assays using spore bio-indicators to ensure sterility when decontaminating with ClO2.
Brain metastasis and treatment (2014)

Despite major therapeutic advances in the management of patients with systemic malignancies, management of brain metastases remains a significant challenge. These patients often require multidisciplinary care that includes surgical resection, radiation therapy, chemotherapy, and targeted therapies. Complex decisions about the sequencing of therapies to control extracranial and intracranial disease require input from neurosurgeons, radiation oncologists, and medical/neuro-oncologists. With advances in understanding of the biology of brain metastases, molecularly defined disease subsets and the advent of targeted therapy as well as immunotherapeutic agents offer promise. Future care of these patients will entail tailoring treatment based on host (performance status and age) and tumor (molecular cytogenetic characteristics, number of metastases, and extracranial disease status) factors. Considerable work involving preclinical models and better clinical trial designs that focus not only on effective control of tumor but also on quality of life and neurocognition needs to be done to improve the outcome of these patients.
An Analysis of the Skype Peer-to-Peer Internet Telephony Protocol (2004)

Skype is a peer-to-peer VoIP client developed by KaZaa in 2003. Skype claims that it can work almost seamlessly across NATs and firewalls and has better voice quality than the MSN and Yahoo IM applications. It encrypts calls end-to-end, and stores user information in a decentralized fashion. Skype also supports instant messaging and conferencing. This report analyzes key Skype functions such as login, NAT and firewall traversal, call establishment, media transfer, codecs, and conferencing under three different network setups. Analysis is performed by careful study of Skype network traffic.
Design of Near-orthogonal Air-gun Sequences for Marine Seismic Source Encoding (2016)

Summary We present a method to design near-orthogonal air-gun firing sequences for applications that exploit sequence orthogonality. We demonstrate that using a simulated annealing approach, we can optimize the autocorrelation and crosscorrelation properties of two sequences. Using a standard air-gun array we show the design of a pair of optimized air-gun firing sequences. The designed sequences are close to orthogonal to each other and provide a significant benefit for simultaneous source separation based on sequence encoding. This new method enables designing tailor-made air-gun firing sequences for multipurpose applications and can easily be extended to include additional design criteria.
Low-Frequency Excess Noise Ratio Approximation for Avalanche Noise Diodes (2019)

This letter deals with microwave noise diodes in avalanche regime. Starting from the model proposed by Hines and Gliden in 1966, the asymptotic excess noise ratio (ENR) expression is derived for ω→0. The developed theory is then validated against ENR measurements of three noise diodes already published in the literature. The agreement between theory and measurements is good and the obtained formula also predicts the 1/I <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> behavior of the ENR at low frequencies. This study is relevant because it simplifies the experimental determination of the average time between two ionizations (the Hines τ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> model parameter) by means of low-frequency noise measurements only.
Dendrons and dendritic catalysts immobilized on solid support: Synthesis and dendritic effects in catalysis (2004)

Abstract Dendrimers, the aesthetically beautiful macromolecules displaying a variety of potentially useful architecture‐induced properties, are traditionally assembled in solution. However, since 1988, a number of dendritic structures have been assembled on insoluble organic and inorganic polymers, and thus dendronized supports have been formed. One of the major applications of these new materials is in the field of heterogeneous catalysis. Supported dendritic catalytic systems, bearing the catalytic units on the dendron periphery, have been examined in the last 5 years in such reactions as hydroformylation, Heck and other Pd‐catalyzed CC bond formations, oxidation, and enantioselective addition to aldehydes. In the majority of these studies, substantial dendritic effects on the reactivity, selectivity, or recyclability of the catalysts were observed. Although a number of factors have been suggested as sources of the effects, it is most likely that the phenomenon has a multicomponent origin. Additional research, including a full determination of the effects and their causes, is likely to lead to markedly better heterogeneous catalytic systems. © 2004 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 43: 235–262, 2005
Progress with 100 mm diameter In/sub 0.53/Ga/sub 0.47/As/InP wafer processing (2003)

Photodetector array results for InGaAs/InP epitaxial layers grown on 50 and 75 mm diameter InP substrates are presented. Best shunt-resistance area products for lattice-matched material exceed 100,000 ohm-cm/sup 2/. X-ray topography results indicate that low defect density (<10,000 cm/sup -2/) iron-doped InP substrates are available in 100 mm diameter. Low dark current results were also obtained with a a "spin-on" zinc diffusion technique whereby the source of zinc is "spun-on" much like a photoresist.
2D TCR–pMHC–CD8 kinetics determines T‐cell responses in a self‐antigen‐specific TCR system (2013)

Two-dimensional (2D) kinetic analysis directly measures molecular interactions at cell-cell junctions, thereby incorporating inherent cellular effects. By comparison, three-dimensional (3D) analysis probes the intrinsic physical chemistry of interacting molecules isolated from the cell. To understand how T-cell tumor reactivity relates to 2D and 3D binding parameters and to directly compare them, we performed kinetic analyses of a panel of human T-cell receptors (TCRs) interacting with a melanoma self-antigen peptide (gp100209 -217 ) bound to peptide-major histocompatibility complex in the absence and presence of co-receptor CD8. We found that while 3D parameters are inadequate to predict T-cell function, 2D parameters (that do not correlate with their 3D counterparts) show a far broader dynamic range and significantly improved correlation with T-cell function. Thus, our data support the general notion that 2D parameters of TCR-peptide-major histocompatibility complex-CD8 interactions determine T-cell responsiveness and suggest a potential 2D-based strategy to screen TCRs for tumor immunotherapy.
Safety and Efficacy Results of a Randomized Trial Comparing Adjuvant Toremifene and Tamoxifen in Postmenopausal Patients With Node-Positive Breast Cancer (2000)

The side-effect profile of toremifene resembles that of tamoxifen. The efficacy of toremifene seems to be no less than that of tamoxifen. The trend for fewer breast cancer recurrences in the ER-positive subgroup is encouraging, but a longer follow-up is needed to confirm this.
An Optimal Tile-Based Approach for Viewport-Adaptive 360-Degree Video Streaming (2019)

In this paper, we propose a new adaptation approach for viewport-adaptive streaming of 360-degree videos over the Internet. The proposed approach is able to systematically decide versions of tiles according to user head movements and network conditions by taking into account not only viewport estimation errors, but also users head movements in each segment duration. The experimental results show that the proposed approach can effectively adapt 360-degree videos to both varying network conditions and user's head movements. Compared to existing approaches, the proposed approach can improve the average viewport quality by up to 3.8 dB and reduce the standard deviation of the viewport quality by up to 1.1 dB. Also, the impacts of the segment duration and the buffer size are investigated. It is found that long segment durations and large buffer sizes have significant impacts on the performances of tile selection methods.
Intraorbital hemorrhage following a secondary intervention at integrated zygomatic implants (2018)

In our case, corrective surgery in a patient with zygomatic implants resulted in an intraorbital hemorrhage, followed by an orbital compression syndrome. Emergency surgery was immediately performed, allowing hematoma drainage and eliminating compression of the intraorbital content. Symptoms quickly resolved and eyesight was not compromised.
Abstract #1962: The Androgen Receptor regulates miR-21 to promote hormone dependent and independent prostate cancer growth (2009)

Abnormal Androgen Receptor (AR) activity contributes to prostate cancer pathogenesis, including hormone refractory disease. However, the downstream AR proliferative pathways are not fully described. We hypothesized that the activated androgen receptor may directly regulate the expression of certain microRNAs (miRNAs), and that these miRNAs may then contribute to the prostate cancer phenotype. In pursuit of these studies, we have established conditions whereby the expected androgen-regulated cell growth and gene expression responses were reproduced in LNCaP and LAPC-4 prostate cancer models. Using these conditions and microarray technology, we evaluated dose-responsive androgen-regulated microRNA expression of over 400 known microRNAs. Here we report the identification of 19 AR responsive miRNAs including the oncogenic miRNA miR-21. We present data demonstrating that miR-21 is directly regulated by the activated AR through chromatin immunoprecipitation assays. This induced miR-21 contributes to androgen induced cell proliferation. Further, we report that ectopic expression of miR-21 alone is sufficient to drive androgen-independent growth. LNCaP cells expressing miR-21 develop more tumors and at an earlier time point than those expressing a vector control. Moreover, miR-21 expressing LNCaP tumors are resistant to castration. Elevated miR-21 expression was also found in human CaP tumors. Collectively, these data place miR-21 in the AR signaling pathway and suggest that miR-21 can contribute to the castration resistant prostate cancer phenotype. Citation Information: In: Proc Am Assoc Cancer Res; 2009 Apr 18-22; Denver, CO. Philadelphia (PA): AACR; 2009. Abstract nr 1962.
Quantification of Carbon Dioxide Using Downhole Wireline Formation Tester Measurements (2006)

Abstract Carbon dioxide (CO2) occurrence in hydrocarbon bearing formations presents a challenge to the valuation and subsequent prospect development of the hydrocarbons. Corrosion is a major concern effecting capital and operational expenditures since the presence of CO2 can cause corrosion failures. Carbon dioxide also denotes an issue for health, safety and the environment (HSE) and is readily absorbed by elastomer seals, weakening the resistance of those seals and compromising the integrity of the fluid samples and the safety of equipment and personnel. The conventional procedure to evaluate the CO2 content in a hydrocarbon bearing formation is to take fluid samples downhole or on surface during a well test and send the fluids to the laboratory for analysis. Both methods are compromised by the reactive nature of CO2, whose concentration can change significantly by reaction with formation waters, mud filtrates, etc. before reaching an analysis facility. Optimizing the fluid sample acquisition program to match existing fluid complexities is impossible without real-time analysis. Recently, NIR (near-infrared) spectroscopy has enabled the real time analysis of the CO2 content in downhole fluid samples. This paper describes a new method for using DFA* (Downhole Fluid Analysis) in the real-time determination of the CO2 amount in the MDT* (Modular Dynamic Formation Tester) flow line. Extensive laboratory data from a research grade spectrometer and shop data with the downhole tool support the new methodology. Multiple interpretation algorithms have been developed for CO2 quantification and verified in the laboratory. Several log examples are given Mark of Schlumberger demonstrating successful CO2 detection and subsequent confirmation of the measured concentrations by the laboratory data.
Communication Optimizations for Distributed-Memory X10 Programs (2011)

X10 is a new object-oriented PGAS (Partitioned Global Address Space) programming language with support for distributed asynchronous dynamic parallelism that goes beyond past SPMD message-passing models such as MPI and SPMD PGAS models such as UPC and Co-Array Fortran. The concurrency constructs in X10 make it possible to express complex computation and communication structures with higher productivity than other distributed-memory programming models. However, this productivity often comes at the cost of high performance overhead when the language is used in its full generality. This paper introduces high-level compiler optimizations and transformations to reduce communication and synchronization overheads in distributed-memory implementations of X10 programs. Specifically, we focus on locality optimizations such as scalar replacement and task localization, combined with supporting transformations such as loop distribution, scalar expansion, loop tiling, and loop splitting. We have completed a prototype implementation of these high-level optimizations, and performed a performance evaluation that shows significant improvements in performance, scalability, communication volume and number of tasks. We evaluated the communication optimizations on three platforms: a 128-node Blue Gene/P cluster, a 32-node Nehalem cluster, and a 16-node Power7 cluster. On the Blue Gene/P cluster, we observed a maximum performance improvement of 31.46x relative to the unoptimized case (for the MolDyn benchmark). On the Nehalem cluster, we observed a maximum performance improvement of 3.01x (for the NQueens benchmark) and on the Power7 cluster, we observed a maximum performance improvement of 2.73x (for the MolDyn benchmark). In addition, there was no case in which the optimized code was slower than the unoptimized case. We also believe that the optimizations presented in this paper will be necessary for any high-productivity PGAS language based on modern object-oriented principles, that is designed for execution on future Extreme Scale systems that place a high premium on locality improvement for performance and energy efficiency.