gebhart/patrepeval huggingface dataset:
Putting Priors in Mixture Density Mercer Kernels (2004)

This paper presents a new methodology for automatic knowledge driven data mining based on the theory of Mercer Kernels, which are highly nonlinear symmetric positive definite mappings from the original image space to a very high, possibly infinite dimensional feature space. We describe a new method called Mixture Density Mercer Kernels to learn kernel function directly from data, rather than using predefined kernels. These data adaptive kernels can en- code prior knowledge in the kernel using a Bayesian formulation, thus allowing for physical information to be encoded in the model. We compare the results with existing algorithms on data from the Sloan Digital Sky Survey (SDSS). The code for these experiments has been generated with the AUTOBAYES tool, which automatically generates efficient and documented C/C++ code from abstract statistical model specifications. The core of the system is a schema library which contains template for learning and knowledge discovery algorithms like different versions of EM, or numeric optimization methods like conjugate gradient methods. The template instantiation is supported by symbolic- algebraic computations, which allows AUTOBAYES to find closed-form solutions and, where possible, to integrate them into the code. The results show that the Mixture Density Mercer-Kernel described here outperforms tree-based classification in distinguishing high-redshift galaxies from low- redshift galaxies by approximately 16% on test data, bagged trees by approximately 7%, and bagged trees built on a much larger sample of data by approximately 2%.
DC WASA Adopts Thermal Hydrolysis for Anaerobic Digestion Pretreatment: Conceptual Design Details for the Largest Cambi™ System (2009)

The District of Columbia Water and Sewer Authority (DC WASA) has decided to incorporate thermal-hydrolysis pretreatment in conjunction with mesophillic anaerobic digestion as the backbone of a long-term biosolids treatment plan to produce Class A biosolids. The Authority has been lime stabilizing their raw solids from the Blue Plains Plant for many years, transporting them to the State of Virginia for land application. DC WASA began the process of identifying an alternative approach to lime stabilization. Selection criteria for the new process included a compact footprint, cost effectiveness, ease of operation by local staff, production of a Class A product, minimization of odor potential, elimination of indicator organism reactivation or regrowth in addition to maximizing energy recovery from biogas. A broad number of alternatives were evaluated and discarded, with thermal hydrolysis and thermal drying as the two remaining alternatives. After evaluating both remaining alternatives, including hybrid of both and sub-alternatives to reduce project cost and eliminate the risk from using only one alternative, thermal hydrolysis in conjunction with mesophillic anaerobic digestion was ultimately chosen as the two processes that best meet the needs of the Authority. This paper summarizes the decision making process for selecting thermal hydrolysis along with the conceptual design for the thermal hydrolysis process.
Design of Turbo Codes over GF(q) with q-ary Orthogonal Modulation (2011)

A very simple design rule for parallel concatenated Turbo codes over GF(q) with q-ary orthogonal modulation is proposed. Unlike previously proposed exhaustive search methods, the proposed design rule allows straightforward and systematic code designs for any value of q ≥ 2 and any constraint length greater than 2.
Wireless offline offload (2016)

Current requirements for vehicular video security systems are making it more challenging to handle the ever-increasing amount of video data produced by the video security systems installed within vehicles. Due to different standard regulations and recommendations, and quite often because of the requirements set by the operators themselves, recorded data not only needs to be stored temporarily within a vehicle's security system, but also needs to be transferred from vehicles to ground systems for more permanent storage. Since public transport systems are most of the time ‘on-the-move’, the time available to transfer the data is limited. Hence, for large fleets of vehicles, wireless transfer, i.e. wireless offload, is preferred over manual swapping of hard disks. Wireless offload, in turn, is not always simple; sometimes it is not even possible to provide sufficient wireless infrastructure for carrying out wireless offload in a timely manner. This paper proposes an alternative wireless offload mechanism, one which allows for cost-efficient offload that is less affected by the insufficient wireless infrastructure.
Supplementary Figure 2 from Intestinal Bacteria Modify Lymphoma Incidence and Latency by Affecting Systemic Inflammatory State, Oxidative Stress, and Leukocyte Genotoxicity (2023)

&lt;p&gt;PDF file - 94K, Effect of Oral Administration of L. johnsonii on Genotoxicity and Inflammation.&lt;/p&gt;
High-Power Terahertz Generation from Telecommunication-Compatible, Bias-Free Photoconductive Nano-Antennas (2018)

We present a telecommunication-compatible, bias-free photoconductive terahertz source with arrays of plasmonic nano-antennas. We demonstrate pulsed terahertz radiation with powers up to 72 μW., enabling time-domain terahertz spectroscopy over a 3 THz bandwidth with a 100 dB dynamic range.
Interaction of 14-3-3 Protein with Regulator of G Protein Signaling 7 Is Dynamically Regulated by Tumor Necrosis Factor-α (2002)

Regulators of G protein signaling (RGS) constitute a family of proteins with a conserved RGS domain of approximately 120 amino acids that accelerate the intrinsic GTP hydrolysis of activated Galpha(i) and Galpha(q) subunits. The phosphorylation-dependent interaction of 14-3-3 proteins with a subset of RGS proteins inhibits their GTPase-accelerating activity in vitro. The inhibitory interaction between 14-3-3 and RGS7 requires phosphorylation of serine 434 of RGS7. We now show that phosphorylation of serine 434 is dynamically regulated by TNF-alpha. Cellular stimulation by TNF-alpha transiently decreased the phosphorylation of serine 434 of RGS7, abrogating the inhibitory interaction with 14-3-3. We examined the effect of 14-3-3 on RGS-mediated deactivation kinetics of G protein-coupled inwardly rectifying K(+) channels (GIRKs) in Xenopus oocytes. 14-3-3 inhibited the function of wild-type RGS7, but not that of either RSG7(P436R) or RGS4, two proteins that do not bind 14-3-3. Our findings are the first evidence that extracellular signals can modulate the activity of RGS proteins by regulating their interaction with 14-3-3.
Microseismic cluster analysis and in-situ stress inversion: A case study from the Cardium Formation, west central Alberta, Canada (2017)

During a hydraulic fracturing operation, microseismic monitoring is a key technique to track and to help understand hydraulically induced fracture systems. In addition to hypocenters, estimated stimulated volume, and overall fracture network geometry, such monitoring can provide failure mechanism information, which can be used for further stress field analysis. In this paper, we introduce a commonly used machine learning method, cluster analysis, into microseismic failure mechanism analysis. It provides a new and automatic approach to analyze spatial failure mechanism variation. In addition, this information can help further spatial in-situ stress inversion. Presentation Date: Wednesday, September 27, 2017 Start Time: 4:45 PM Location: 362D Presentation Type: ORAL
The Ongoing Importance of Lithium Primary Batteries: 50+ Years and Going Strong (2022)

Lithium anode primary batteries display numerous outstanding characteristics including high energy density, long shelf life, low self-discharge, and ability to function under a broad temperature operating range. This has led to the design and implementation of lithium primary cells for a variety of applications in the commercial, military, space, and medical fields. The development of these primary batteries has required understanding and resolution of complex reaction mechanisms as well as optimized electrode and cell designs to meet the needs of the target applications. Notably, a variety of cathode materials have been paired with lithium metal anodes including carbon monofluoride (CFx), manganese oxide (MnO 2 ), thionyl chloride (SOCl 2 ), and sulfur dioxide (SO 2 ). A specific application of primary lithium battery systems is to power implantable medical devices. These primary systems utilize lithium metal anodes with cathodes such as iodine, manganese oxide, carbon monofluoride, silver vanadium oxide, and hybrid cathodes. While the specific performance requirements of applications vary, lithium batteries can provide the solutions for single use power source needs.
Streptozotocin-Induced Astrocyte Mitochondrial Dysfunction Is Ameliorated by FTO Inhibitor MO-I-500 (2021)

The pathogenesis of Alzheimer’s disease (AD), the most prevalent form of dementia, remains unclear. Over the past few years, evidence has accumulated indicating that perturbed cerebral bioenergetics and neuroinflammation may compromise cognitive functions and precedes the onset of AD and that impaired function of glial cells can likely contribute to the development of the disease. Recently, N6-methyladenosine (m6A) modification of RNA has been implicated in the regulation of different processes in the brain and to play a potential role in neurodegeneration. In the present study, we investigated the potential role of the m6A machinery enzymes in a streptozotocin (STZ) model of AD in human astrocytoma CCF-STTG1 cells. We observed that STZ-treated astrocytes expressed significantly higher levels of m6A demethylase fat mass and obesity-associated protein (FTO) and m6A reader YTHDF1 (YTH domain-containing family protein 1). Our experiments revealed that MO-I-500, a novel pharmacological inhibitor of FTO, can strongly reduce the adverse effects of STZ. Inhibition of FTO enhanced the survival of cells exposed to STZ and suppressed oxidative stress, apoptosis, elevated expression of glial fibrillary acidic protein, mitochondrial dysfunction, and bioenergetic disturbances induced by this compound. Overall, the results of this study indicate that perturbed m6A signaling may be contributing to AD pathogenesis, likely by compromising astrocyte bioenergetics.
FRET-Assisted Deep-Blue Electroluminescence in Intercalated Polymer Hybrids (2014)

Polymer/layered silicate nanocomposites (PSNs), obtained through a bottom-up strategy with both free and intercalated poly(styrene) carrying fluorescent terfluorene side-chains, allow for the fabrication of optically transparent films with controlled morphology and fine-tuning of the organic/inorganic interface properties. The successful assessment of the hybrid material as an efficient emitter in a light-emitting device is reported, and the complex mechanism responsible for its emission is elucidated. The approach allows planarization and chemical and photostabilization of short intercalated oligo(fluorene)s whose emissive properties are enhanced thanks to exciton localization. Both photoluminescence and electroluminescence are assisted by a sensitization mechanism exploiting resonant energy transfer from nonplanar, nonintercalated polymer pendant conformers wrapping the silicates. A single-layer, solution-processable, hybrid light emitting diode (LED) displays deep-blue electroluminescence with a record external quantum efficiency, for this class of materials, of 1.2%, maximum luminance of 860 cd/m2, Commission Internationale de l’Eclairage (CIE) 1931 (x, y) chromaticity coordinates of (0.158, 0.114), and low efficiency roll-off thanks to the separation of the emissive region from the charge transport one.
Tackling Bet v 1 and associated food allergies with a single hybrid protein (2016)

Directed epitope rearrangements combined with a knowledge-based structural modification resulted in a protein unable to bind IgE from allergic patients. Still, properties to activate specific T cells or induce blocking antibodies were conserved. This suggests that MBC4 is a suitable vaccine candidate for the simultaneous treatment of Bet v 1 and associated food allergies.
Physical mechanisms responsible for short channel effects in MOS devices (1981)

The physical mechanisms responsible for short-channel effects in MOS devices are described. It is shown that short-channel effects are caused by the penetration of junction fields into the channel region. These fields effectively decrease the substrate doping, thus leading to a lower threshold voltage and a larger depletion region depth. Computer simulations explicitly verify the lower effective substrate doping and larger depletion depth in short-channel devices. The junction fields are found to decay exponentially with distance from the junction edges and to vary sinusoidally in the vertical direction. Both the decay length and the wave length are found to be proportional to (3t <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">ox</inf> + W <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">c</inf> ). The usefulness of the new physical understanding is demonstrated in a comparison of the short-channel effects of conventional and buried channel MOSFETs using both computer simulation and experimental results. Some of the limitations of charge sharing models are also discussed.
k-Space Tomography for Spatial-Spectral Mapping (2018)

Simultaneous detection of radio waves' frequency and angle of arrival is achieved by coherent optical processing. This technique uses a fiber length dispersion array coupled to a distributed antenna array to provide unique CCD-captured interferograms for computational tomographic reconstruction of the radio frequency signal environment.
nCPAP Improves the Quality of Life of Siblings with Mandibuloacral Dysplasia (2011)

Mandibuloacral dysplasia (MAD; MIM 248370, 608612) is a rare progeroid syndrome with autosomal recessive inheritance. It is characterized by mandibular hypoplasia, acroosteolysis, delayed closure of the cranial sutures, skin atrophy with mottled hyperpigmentation, stiff joints, and growth retardation. We here report Japanese female siblings with a severe MAD phenotype. Because of extreme micrognathia and small mouth and nostril, obstructive sleep apnea syndrome (OSAS) was observed in both sisters and was especially life-threatening in the younger sister. Nasal continuous positive airway pressure (nCPAP), which seemed to be only one therapeutic choice for these sisters since impaired bone healing made oral surgical approach including maxillomandibular advancement surgery inapplicable to these sisters, successfully alleviated OSAS in both sisters. Since the initiation of nCPAP, the younger sister has gained weight constantly and her developmental milestones have been steadily achieved. We conclude that possible life threatening sleepdisordered breathing in the patients with progeroid syndromes should be properly managed.
Domain Pinning: Comparison of Hafnia and PZT Based Ferroelectrics (2017)

Even though many studies on the field cycling behavior of ferroelectric hafnium oxide have recently been published, the issue is still not fully understood. The initial increase of polarization during first cycles is explained by different theoretical and empirical approaches. Field‐induced phase changes as well as oxygen vacancy diffusion from interfacial layers toward the bulk are discussed. Trapped charges as well as the mentioned oxygen vacancy diffusion might cause a shift of the hysteresis along the voltage axis called imprint. Even though various studies connect this effect to charge diffusion with progression of cycling, a final experimental proof for the origin of wake‐up and imprint is still missing. Based on the comprehensive comparative study of hafnia–zirconia and iron‐doped lead zirconate titanate ferroelectrics, it is verified that the diffusion of oxygen vacancies is the main cause for both imprint and wake‐up. Moreover, it is shown that a local seed inhibition of ferroelectric domains is most likely responsible for the reduced ferroelectric response in pristine state.
Efficient Polarized Laser Mirror (1998)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text R. Magnusson, Z. S. Liu, D. Shin, S. Tibuleac, and P. P. Young, "Efficient Polarized Laser Mirror," Optics & Photonics News 9(12), 35-36 (1998) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Inhibition of Allergen-Induced Histamine Release from Human Basophils by Cyclosporine A and FK-506 (1997)

A number of structurally different allergens trigger the release of mediators from basophils by cross-linking of IgE receptors. In this study, we analyzed the effects of cyclosporine A (CSA) and FK-506 on allergen-induced histamine release in human blood basophils obtained from birch- or grass-pollen-allergic donors (n = 12). Preincubation of basophils with CSA (0.003-3 microg/ml) or FK-506 (0.003-3 microg/ml) led to inhibition of histamine release induced by purified recombinant tree pollen allergens (r Bet v 1, r Bet v 2) and timothy grass pollen allergens (r Ph1 p 1, r Ph1 p 2, r Ph1 p 5). The effects of CSA and FK-506 were dose dependent, with IC50 values ranging between 0.03 and 0.3 microg/ml for both CSA and FK-506. Cyclosporine H, an inactive CSA analog, did not show any effect on allergen-induced histamine secretion. IgE dependency of the reaction was demonstrated in passive transfer experiments using highly enriched human basophils (> 95% pure) and specific IgE from a patient allergic to Bet v 2. In summary, our data show that CSA and FK-506 inhibit recombinant-allergen-induced histamine release from peripheral blood basophils in allergic donors.
<title>Three-dimensional image representation of buildings utilizing heterogeneous information for multimedia ambiance communication</title> (2003)

The Multimedia Ambiance Communication project has been researched and developed using 3D image space that is shared by people in different locations. In this communication, 3D space is constructed of layered structure defined for long-range, middle-range, short-range views. This research especially focuses on buildings in the middle-range view. We acquire 3D data of buildings using a range scanner and texture data, and represent them in VR space. In the case of real buildings, restrictions result in the acquisition of partial data. To compensate for this, other information such as drawings, photographs, general knowledge, etc, were used. The authors detail the construction of photo-realistic representation of buildings and 3D space.
Hypothetical generalized framework for a new imaging endpoint of therapeutic activity in early phase clinical trials in brain tumors (2022)

Imaging response assessment is a cornerstone of patient care and drug development in oncology. Clinicians/clinical researchers rely on tumor imaging to estimate the impact of new treatments and guide decision making for patients and candidate therapies. This is important in brain cancer, where associations between tumor size/growth and emerging neurological deficits are strong. Accurately measuring the impact of a new therapy on tumor growth early in clinical development, where patient numbers are small, would be valuable for decision making regarding late-stage development activation. Current attempts to measure the impact of a new therapy have limited influence on clinical development, as determination of progression, stability or response does not currently account for individual tumor growth kinetics prior to the initiation of experimental therapies. Therefore, we posit that imaging-based response assessment, often used as a tool for estimating clinical effect, is incomplete as it does not adequately account for growth trajectories or biological characteristics of tumors prior to the introduction of an investigational agent. Here, we propose modifications to the existing framework for evaluating imaging assessment in primary brain tumors that will provide a more reliable understanding of treatment effects. Measuring tumor growth trajectories prior to a given intervention may allow us to more confidently conclude whether there is an anti-tumor effect. This updated approach to imaging-based tumor response assessment is intended to improve our ability to select candidate therapies for later-stage development, including those that may not meet currently sought thresholds for "response" and ultimately lead to identification of effective treatments.
A method for modeling household occupant behavior to simulate residential energy consumption (2014)

This paper presents a statistical method for modeling the behavior of household occupants to estimate residential energy consumption. Using data gathered by the U.S. Census Bureau in the American Time Use Survey (ATUS), actions carried out by survey respondents are categorized into ten distinct activities. These activities are defined to correspond to the major energy consuming loads commonly found within the residential sector. Next, time varying minute resolution Markov chain based statistical models of different occupant types are developed. Using these behavioral models, individual occupants are simulated to show how an occupant interacts with the major residential energy consuming loads throughout the day. From these simulations, the minimum number of occupants, and consequently the minimum number of multiple occupant households, needing to be simulated to produce a statistically accurate representation of aggregate residential behavior can be determined. Finally, future work will involve the use of these occupant models along side residential load models to produce a high-resolution energy consumption profile and estimate the potential for demand response from residential loads.
Graphics Processing Units for Handhelds (2008)

During the past few years, mobile phones and other handheld devices have gone from only handling dull text-based menu systems to, on an increasing number of models, being able to render high-quality three-dimensional graphics at high frame rates. This paper is a survey of the special considerations that must be taken when designing graphics processing units (GPUs) on such devices. Starting off by introducing desktop GPUs as a reference, the paper discusses how mobile GPUs are designed, often with power consumption rather than performance as the primary goal. Lowering the bus traffic between the GPU and the memory is an efficient way of reducing power consumption, and therefore some high-level algorithms for bandwidth reduction are presented. In addition, an overview of the different APIs that are used in the handheld market to handle both two-dimensional and three-dimensional graphics is provided. Finally, we present our outlook for the future and discuss directions of future research on handheld GPUs.
Stochastic-Geometry-Based Interference Modeling in Automotive Radars Using Matérn Hard-Core Process (2020)

As the use of radars in autonomous driving systems becomes more prevalent, these systems are increasingly susceptible to mutual interference. In this paper, we employ stochastic geometry to model the automotive radar interference in realistic traffic scenarios and then derive trade-offs between the radar design parameters and detection probability. Prior works model the locations of radars in the lane as a homogeneous Poisson point process (PPP). However, the PPP models assume all nodes to be independent, do not account for the lengths of vehicles, and ignore spatial mutual exclusion. In order to provide a more realistic interference effect, we adopt the Matérn hardcore process (MHCP) instead of PPP, in which two vehicles are not closer than an exclusion radius from one another. We show that the MHCP model leads to more practical design trade-offs for adapting the radar parameters than the conventional PPP model.