gebhart/patrepeval huggingface dataset:
Small-signal analytical MOSFET model for microwave frequency applications (2000)

A small-signal analytical MOSFET model suitable for microwave frequency applications is presented. The effect of parasitic elements, the fringing-field effect, and distributed-gate inductance also have been incorporated. The generalized expression for Id–Vd characteristics is given, and the admittance parameters extracted are expressed as a function of the MOSFET parameters, parasitic elements, frequency, and bias conditions. The theoretical predictions are compared with experimental/simulated data, and are in good agreement. © 2000 John Wiley & Sons, Inc. Microwave Opt Technol Lett 25: 346–352, 2000.
Supplementary Methods from Novel Anti-TM4SF1 Antibody–Drug Conjugates with Activity against Tumor Cells and Tumor Vasculature (2023)

&lt;p&gt;Supplementary Methods&lt;/p&gt;
Using Ptides and synchronized clocks to design distributed systems with deterministic system wide timing (2013)

This paper discusses the use of the Ptides model of computation as a coordination language for the design of deterministic, event-driven, real-time, distributed embedded systems. Specifically, the paper shows how the use of synchronized clocks in the context of Ptides enables explicit, platform independent specification of functionality and timing. From this specification, we generate code for two target platforms: Renesas and XMOS. The generated code includes a lightweight operating system which performs scheduling, I/O and network handling as well as application specific tasks. Ptides models are developed in Ptolemy, a design and simulation environment for heterogeneous systems. This framework also contains a code generation framework which is leveraged to derive Ptides implementations from the models. We illustrate our approach by designing a simple Ptides application, a small component in a printing press responsible for on-the-fly changeover between paper rolls. We demonstrate the design process and show that the generated code exhibits identical timing at the cyber-physical boundary on multiple implementation platforms.
Deoxynucleotide substitution: a new technique for sequence analysis of RNA (1974)

It is possible to replace in a normal transcription reaction catalyzed by E.coli RNA polymerase one of the four precursors by the corresponding deoxynucleoside triphosphate. These deoxynucleotide-substituted RNA's offer interesting prospects for nucleotide sequence analysis. Indeed by the use of U(2)-RNase with dG-RNA, or pancreatic RNase with dC-RNA or dU-RNA, base specific cleavage can be obtained at any of the four residues. In this way overlap of at least six residues in length can be obtained for any site in the RNA. The technique offers also great benefit for solving the sequence of the more difficult T(1)-oligonucleotides. Some examples in the sequence analysis of SV40 DNA-Hind fragments are reported.
Empirical mode decomposition approach to the estimation of cardiac baroreflex sensitivity in patients undergoing coronary artery bypass graft surgery (2014)

Cardiac baroreflex sensitivity (BRS) as assessed from spontaneous variability of heart period (HP) and systolic arterial pressure (SAP) is reduced during general anesthesia. Patients undergoing coronary artery bypass graft (CABG) surgery are characterized by a low BRS even before general anesthesia. These observations provide the basis of the difficulty in detecting the BRS reduction after the induction of general anesthesia in CABG patients. Empirical mode decomposition (EMD) is a technique decomposing the series into oscillatory modes at different time scales. We propose an EMD-based approach to the BRS estimate in 34 patients undergoing CABG. Results showed that the EMD-based method was not able to detect the BRS reduction in CABG patients after the induction of general anesthesia. The negative result was interpreted as a consequence of the inability of EMD-based method to account for HP-SAP causality.
The Timing of In Memoriam (1981)

In Memoriam, of all the really important long works of Victorian prose or poetry, is probably the one about whose composition the least information survives. Of the poem's 133 sections—131 numbered sections plus the so-called 'prologue' and 'epilogue'—less than one-fifth can be dated with certainty. A further third can be assigned dates of composition which are more or less tentative. And the growth of the general design of the poem is also controversial. We have Tennyson's own word for the fact that the earliest component sections were written without any idea of 'weaving' them together (to use his own striking term), but we do not know when Tennyson started to compose verses consciously designed for inclusion in a long poem about Hallam's death.KeywordsOuter WorldImplicit ContentRomantic PoetryRhetorical CategoryPoet LaureateThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
ChemInform Abstract: Synthesis and Biological Activity of Trisubstituted Adenines as A2A Adenosine Receptor Antagonists (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Réflectométrie holographique numérique appliquée à la métrologie des fluides (2010)

Keywords: [MVD] Reference EPFL-CONF-154009 Record created on 2010-11-01, modified on 2017-05-10
Release kinetics and concentration profile of dissolved silicon in compacted sediments (1997)

The kinetics of release of dissolved silicon from river sediments under close to natural conditions have been studied on the basis of a semi-infinite diffusion model taking into account the dissolution of the support. A new theoretical framework suitable for the description and modelling of such processes has been developed and the numerical solution compared with the asymptotic behaviour at short times. The dynamics of the concentration profile of dissolved silicon in the sediment phase has been calculated, and by adjusting the model parameters to the experimental data on concentration profiles measured in a natural sediment and a fluvarium channel bed, reliable estimates for the diffusion coefficient and generation rate constant have been obtained.
Thermoelectric properties of layered oxyselenides La1−xSrxCuOSe (x=0 to 0.2) (2004)

Thermoelectric properties of layered oxyselenides La1−xSrxCuOSe (x=0.00 to 0.20) were investigated to evaluate the potential as thermoelectric material. Temperature dependence of the electrical conductivity and Seebeck coefficient measured in a temperature range of 373 to 673 K indicated that nondoped LaCuOSe was a p-type degenerate semiconductor due to Cu vacancies, while Sr-doped materials with x=0.05 to 0.20 were p-type metals. The electrical conductivity increased and Seebeck coefficient decreased with increasing Sr concentration up to x=0.10 in La1−xSrxCuOSe, suggesting that the effective hole carriers increase with increasing Sr content up to x=0.10. Thermoelectric power factors were drastically enhanced by the Sr doping, and the value reached 1.0−1.4×10−4 W m−1 K−2 for La0.95Sr0.05CuOSe. Thermal conductivities measured for the materials with x=0.00 and 0.05 were 2.1 W m−1 K−1 and 2.3 W m−1 K−1 at room temperature, respectively. These results lead to an estimation of Z value of 4.4×10−5 K−1 for La0.95Sr0.05CuOSe.
ChemInform Abstract: Mo[N(t‐Bu)(Ar)]3 Complexes as Catalyst Precursors: In situ Activation and Application to Metathesis Reactions of Alkynes and Diynes. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Estimation of cerebrospinal fluid compensation parameters in hydrocephalus using short-lasting constant rate lumbar infusion tests (2011)

The lumbar infusion test may be shortened to 10-15 min using a rapid infusion rate of 2 ml/min that fulfils the primary objective of obtaining reliable estimates of R(out). This may benefit patients who do not tolerate the full procedure.
Colors of graphene and graphene-oxide multilayers on various substrates (2011)

We investigated the colors of graphene and graphene-oxide multilayers that were deposited on various dielectric layers. In particular, the effects of the material thickness, the types of dielectric layers, and the existence of a back silicon substrate were analyzed. The colors of graphene-oxide layers on a SiO2/Si substrate were found to periodically change as the material thickness increased. However, the colors of graphene layers on the same substrate became saturated without a similar periodic change. The calculated colors corresponding to the material thicknesses were verified by optical microscopy and profilometry. We believe that these results demonstrate the possibility of utilizing color as a simple tool for detecting and estimating the thicknesses of graphene and graphene-oxide multilayers.
NBNgain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer (2014)

Despite the use of clinical prognostic factors (PSA, T-category and Gleason score), 20-60% of localized prostate cancers (PCa) fail primary local treatment. Herein, we determined the prognostic importance of main sensors of the DNA damage response (DDR): MRE11A, RAD50, NBN, ATM, ATR and PRKDC. We studied copy number alterations in DDR genes in localized PCa treated with image-guided radiotherapy (IGRT; n=139) versus radical prostatectomy (RadP; n=154). In both cohorts, NBN gains were the most frequent genomic alteration (14.4 and 11% of cases, respectively), and were associated with overall tumour genomic instability (p<0.0001). NBN gains were the only significant predictor of 5yrs biochemical relapse-free rate (bRFR) following IGRT (46% versus 77%; p=0.00067). On multivariate analysis, NBN gain remained a significant independent predictor of bRFR after adjusting for known clinical prognostic variables (HR=3.28, 95% CI 1.56-6.89, Wald p-value=0.0017). No DDR-sensing gene was prognostic in the RadP cohort. In vitro studies correlated NBN gene overexpression with PCa cells radioresistance. In conclusion, NBN gain predicts for decreased bRFR in IGRT, but not in RadP patients. If validated independently, Nibrin gains may be the first PCa predictive biomarker to facilitate local treatment decisions using precision medicine approaches with surgery or radiotherapy.
Two I mmunoglobulin G F ragment C R eceptor P olymorphisms Independently P redict R esponse t o R ituximab i n P atients W ith Follicular L ymphoma (2003)

Purpose: Although rituximab is now routinely used in the treatment of B-cell non-Hodgkin’s lymphoma, the mechanism of its antitumor effect is not clear. One potential mechanism of action involves antibody-dependent cellular cytotoxicity (ADCC). Two aspects of ADCC influence the effectiveness of this process: the susceptibility of tumor cells and the activation of effector cells via their immunoglobulin G fragment C receptors (FcRs). Several FcR polymorphisms have been identified that may affect the killing function of natural killer cells and macrophages. Patients and Methods: The pretreatment tumor cells from 43 patients with follicular lymphoma were tested for their intrinsic susceptibility to rituximab-mediated ADCC. In addition, the FcRIIIa (CD16) and FcRIIa (CD32) polymorphisms were determined in an expanded group of 87 patients. The results were then correlated with clinical outcome of these patients. Results: No difference was found between the susceptibility of tumors from patients who clinically responded to rituximab versus those who did not respond. Conversely, both the FcRIIIa 158 valine/valine and the FcRIIa 131 histidine/histidine genotypes were found to be independently associated with the response rate and freedom from progression. Conclusion: These data support the hypothesis that ADCC plays an important role in the clinical effect of rituximab at the level of the effector cell. It will be important to include information on Fc receptor polymorphisms in future trials of rituximab therapy. J Clin Oncol 21:3940-3947. © 2003 by American Society of Clinical Oncology.
Interactive CFD Ventilation Model for AIT Support (2007)

&lt;div class="htmlview paragraph"&gt;The on-orbit performance verification of the functions constituting a Space Manned System is one of the critical points of space projects.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;During phase C/D of Node 2 &amp;amp; 3 and ATV Space station modules, the Alcatel Alenia Space - Italia approach for the verification of the design requirements related to the correct air distribution inside the Module habitable volume was to use a CFD virtual mock-up, derived by CAD models. These models were correlated with existing on ground ventilation tests and were extensively used during the project phase to evaluate the impact on the relevant ventilation requirements of possible internal module layout changes and item relocations.&lt;/div&gt; &lt;div class="htmlview paragraph"&gt;This paper describes the developed tool capability and presents the results obtained in support to the Assembly, Integration and Test (AIT) phases.&lt;/div&gt;
Optimized Design of a Digital IQ Demodulator Suitable for Adaptive Predistortion of 3rd Generation Base Station PAs (2006)

This paper presents an optimized design of a high-speed digital IQ demodulator intended for the implementation of the feedback path of an adaptive base band pre-distorter (DPD). Indeed, the optimization of the DPD linearization capability in terms of correction bandwidth and nonlinearity effects minimization is directly related to the accuracy and speed of the IQ demodulator. In this work, a digital IQ demodulator is designed, optimized and implemented in a Xilinx FPGA device. This allowed a high speed processing of about 200MHZ with a substantial reduction of the FPGA used gates.
Time–Space Compression (2022)

Time-Space Compression is one of the most influential concepts in globalization theory. Focused by David Harvey in 1990 on spatial shrinkage and temporal simultaneity, it offered an account of the metaphorical contraction of the globe in relation to travel speed. This chapter explores its legacy, and argues that, since 1990, the economic and cultural meanings of time-space compression have shifted towards a conception of uncertainty: it aims to show that the vocabulary has changed in order to break with a kind of complicity that social theory has identified between capitalist expansion and social-scientific commentary. Time-space compression has turned away from the emphasis on global simultaneity, towards questions about the knowability of the future. Bernard Stiegler is one theorist who has developed a new account of epochal temporality for the digital age which has transformed canonical notions of time-space compression by giving them a future orientation. Stiegler’s work also offers us ways of thinking about narrative as a form of belatedness, and about the way that the interval between events and their reception might be eliminated by the inner forms of narrative and the novel.
Facies analysis from pre‐stack inversion results in a deep offshore turbidite environment (2005)

In a companion paper (Nivlet et al.,2005), we have described an application of seismic pre‐stack inversion to retrieve acoustic and shear impedance models in Girassol field. The next step, which will be discussed in this paper, is the lithoseismic interpretation of the inversion results. Traditional seismic facies analysis consists in extracting various amplitude maps of a reservoir level, and producing probabilistic or deterministic seismic facies maps. In this paper, we will present a workflow reaching beyond this traditional approach, by producing a 3D geological facies proportion model, which can then be used as a direct constraint to high resolution geological modeling techniques. The workflow consists of 5 main steps: • well log interpretation calibrated on core data; • upscaling of the facies database at the seismic scale; • choice of appropriate seismic attributes to discriminate betweenn the different facies, compensating for instance for the shale compaction with depth; • probabilistic seismic facies analysis from the chosen seismic attribute cubes supervised by upscaled well information; • post‐interpretation of seismic facies analysis results in terms of mean proportions of geological facies; • consistency check between the facies model and seismic impedances.
Comparative genomic hybridization analysis of chromosomal changes occurring during development of acquired resistance to cisplatin in human ovarian carcinoma cells (1997)

The genetic changes underlying the development of resistance to the platinum-containing drugs are poorly defined. We analyzed six resistant cell lines using comparative genomic hybridization (CGH) in order to screen and identify possible genetic changes in common. We compared parental 2008 and A2780 human ovarian cancer cells to sublines selected for resistance to cisplatin (DDP) (2008/C8, 2008/C13*5.25, 2008/A, A2780/CP); we also compared 2008 cells to sublines selected for resistance to antimonite (2008/H) and arsenite (2008/I) which demonstrated cross-resistance to DDP. DNA samples from the resistant cell lines were hybridized against DNA from the parental cells rather than from normal human cells to permit detection of only those changes associated with the development of resistance. The DNA sequence copy number changes were surprisingly numerous in the DDP, antimony, and arsenite-resistant variants of the 2008 cell line and most of the chromosomes were affected. On the other hand, in the A2780/CP subline only a few changes were found and these were limited to just four chromosomes. The most common findings among the DDP-resistant cell lines were gains of material from chromosomes or chromosome arms 2q (5 out of 6 lines), 4 (4/6), 6q (5/6), and 8q (4/6). Deletions were observed on chromosomes or chromosome arms 2p (4/6), X (4/6), 7p (5/6), 11p (4/6), and 13 (4/6). The most frequently involved chromosomal regions, affected in the majority of cell lines, were: gain of 2q14.1–q33, 4p15.2–p13, 4q22–q25, 4q31.1–q34, 6q13–q16, 8q12–q21.2, and loss of Xp22.2–q21, 7p21–p14, 11cen-p14 in sublines of 2008, and loss of 2pter-p22 and 13q21 in sublines of 2008 and A2780. The results suggest that the acquired resistance and cross-resistance to DDP in these cell lines was associated with substantial genomic instability, quite unlike the changes observed in association with the development of resistance to drugs participating in the multidrug resistance phenotype. Genes Chromosom. Cancer 18:286–291, 1997. © 1997 Wiley-Liss, Inc.
Effects of UV-C Irradiation and Vacuum Sealing on the Shelf-Life of Beef, Chicken and Salmon Fillets (2023)

One-third of the world’s food supply is lost, with meat being a major contributor to this loss. Globally, around 23% of all meat and 35% of all seafood products are lost or wasted. Meats and seafood products are susceptible to microbial spoilage during processing, storage, and distribution, where microbial contamination causes significant losses throughout the supply chain. This study examined the efficacy of UV-C irradiation and vacuum-sealing in preventing microbiological deterioration in beef, chicken, and salmon fillets. The samples were sterilized using a constant UV-C irradiation dose of 360 J/m2 and stored under a reduced pressure of 40 kPa. A microbiological analysis was conducted daily to examine the microbial contamination, which included counting the colonies of Pseudomonas spp., aerobic bacteria, lactic acid bacteria (LAB), Salmonella, and Escherichia coli, as well as monitoring the increase in pH levels. The results demonstrated a statistically significant difference (p &gt; 0.05) in the aerobic bacteria counts between the storage conditions and storage days in all samples, which is a primary indicator of microbial spoilage. In contrast, the differences varied in the Pseudomonas spp. and LAB counts between the storage conditions and storage days, and there was no significant difference (p &lt; 0.05) in the pH levels between the storage conditions. The results indicate that the combination of UV-C irradiation and vacuum sealing effectively inhibits microbial growth and extends the shelf-life of beef, chicken, and salmon fillets by 66.6%.
Open-Domain Question Answering with Pre-Constructed Question Spaces (2021)

Jinfeng Xiao, Lidan Wang, Franck Dernoncourt, Trung Bui, Tong Sun, Jiawei Han. Proceedings of the 2021 Conference of the North American Chapter of the Association for Computational Linguistics: Student Research Workshop. 2021.
Highly variable anticoagulant response after subcutaneous administration of high-dose (12,500 IU) heparin in patients with myocardial infarction and healthy volunteers. (1992)

Subcutaneous administration of heparin in a fixed dose for prophylactic and therapeutic purposes may be inadequate because of the large interindividual and intraindividual variations in anticoagulant effect.
Catalytic bio–chemo and bio–bio tandem oxidation reactions for amide and carboxylic acid synthesis (2014)

Oxygen-dependent enzymes and chemocatalysts were combined to provide one-pot tandem cascade syntheses of amides and carboxylic acids.
Work Stress and Low Sense of Coherence Is Associated With Type 2 Diabetes in Middle-Aged Swedish Women (2003)

This study provided new evidence that stress factors such as low decision latitude at work and low SOC were associated with type 2 diabetes in middle-aged Swedish women.
Characterization of mammary-derived growth factor 1 receptors and response in human mammary epithelial cell lines. (1990)

Mammary-derived growth factor 1 (MDGF1, with a molecular mass of 62 kDa and pI of 4.8) has been purified from human milk (Bano, M., Salomon, D. S., and Kidwell, W. R. (1985) J. Biol. Chem. 260, 5745-5752). N-terminal sequence of 18 amino acids showed no homology to any known growth promoting peptides. The present study was carried out to evaluate the biological effects of and binding sites for MDGF1 on normal human and breast cancer cell lines. At a concentration of 10-25 ng/ml the factor stimulated the growth of estrogen receptor-positive MCF-7 human breast cancer cells by 50% and also stimulated the synthesis of collagen IV by 40%. It did not have any effect on ZR75-1, T47-D, and MDA-MB 231 cells. The factor showed a biphasic effect on the estrogen receptor-negative MDA-MB 468 cells at concentrations above 5 ng/ml. The growth of normal human mammary epithelial cells (184 strain) was enhanced by 35%, whereas immortalized non-tumorigenic 184A1N4 human mammary epithelial cells were stimulated by about 60-70%. However, transformation of these cells by SV40-T, v-Ha-ras, or v-mos desensitized them to MDGF1. Iodinated MDGF1 binds to moderate affinity sites on the responsive MCF-7, MDA-MB 468, and 184A1N4 cell lines (KD = 6 x 10(-9) M). Cross-linking of 125I-MDGF1 to binding sites revealed the presence of a major band of molecular mass of approximately 180-200 kDa in MCF-7 and MDA-MB 468 cell lines. Labeling of this band was inhibited by excess unlabeled MDGF1. These data suggest that human mammary epithelial cell lines possess receptors for MDGF1.
Factors Associated with Time to Conversion from Active Surveillance to Treatment for Prostate Cancer in a Multi-Institutional Cohort (2021)

A shorter time to conversion from active surveillance to treatment was associated with higher-risk clinicopathological tumor features. Furthermore, patients with high-volume GG1 tumors behaved similarly to those with intermediate and high-risk tumors. An exploratory analysis of self-reported race and genetic ancestry revealed no association with the time to conversion.