gebhart/patrepeval huggingface dataset:
Blockchain analytics and artificial intelligence (2019)

Blockchain records track information about financial payments, movements of products through supply chains, identity verification information, and many other assets. Analytics on this data can provide provenance histories, predictive planning, fraud identification, and regulatory compliance. In this paper, we describe analytics engines connected to blockchains to provide easy-to-use configurable dashboards, predictive models, provenance histories, and compliance checking. We also describe how blockchain data can be combined with external data sources for secure and private analytics, enable artificial intelligence (AI) model creation over geographically dispersed data, and create a history of model creation enabling provenance and lineage tracking for trusted AI.
Use of supercapacitors to enhance the lifetime and efficiency of road vehicle batteries (2022)

The work presented here originates from the participation in the sixth edition of the IEEE VTS Motor Vehicles challenge, which dealt with the design of a hybrid dual energy storage system on board of an electric vehicle - a solution expected to improve their overall lifetime and efficiency. In particular, contenders were required to size the battery cells and supercapacitor modules installed in the vehicle properly and implement an energy management system to control them to minimize specific desiderata. This paper outlines three strategies proposed for the challenge and describes their effects on particular variables of interest, such as battery current and supercapacitor pack voltage.
Complement C3 and C5 Deficiency Affects Fracture Healing (2013)

There is increasing evidence that complement may play a role in bone development. Our previous studies demonstrated that the key complement receptor C5aR was strongly expressed in the fracture callus not only by immune cells but also by bone cells and chondroblasts, indicating a function in bone repair. To further elucidate the role of complement in bone healing, this study investigated fracture healing in mice in the absence of the key complement molecules C3 and C5. C3(-/-) and C5(-/-) as well as the corresponding wildtype mice received a standardized femur osteotomy, which was stabilized using an external fixator. Fracture healing was investigated after 7 and 21 days using histological, micro-computed tomography and biomechanical measurements. In the early phase of fracture healing, reduced callus area (C3(-/-): -25%, p=0.02; C5(-/-): -20% p=0.052) and newly formed bone (C3(-/-): -38%, p=0.01; C5(-/-): -52%, p=0.009) was found in both C3- and C5-deficient mice. After 21 days, healing was successful in the absence of C3, whereas in C5-deficient mice fracture repair was significantly reduced, which was confirmed by a reduced bending stiffness (-45%; p=0.029) and a smaller callus volume (-17%; p=0.039). We further demonstrated that C5a was activated in C3(-/-) mice, suggesting cleavage via extrinsic pathways. Our results suggest that the activation of the terminal complement cascade in particular may be crucial for successful fracture healing.
Oral complaints caused from metastases to the mandible and maxilla. (2007)

Jaw bone disorders causing oral complaints are common in primary care settings. Most of these conditions are of a chronic and benign nature. However they also may be the symptoms of a primary or secondary malignant process in the bone. The most common malignant bone tumor is metastatic carcinoma, and tumors arising in the breast, prostate, thyroid, lung and kidney have a special propensity to spread to bone. Yet metastases to the bones are rare; less than one per cent of all neoplasms metastases to the maxillofacial area. We describe four cases of metastatic tumours to the jaws. Two cases originated from the thyroid gland while the rest were from the oesophagus and the liver respectively. Three lesions occurred in the mandible and one in the maxilla. Patients presented with oral discomforts disregarding the primary tumor. Physicians who frequently advise patients with oral complaints should keep in mind that whereas these symptoms are mostly of a chronic and benign nature, metastases from a malignant tumor must be included in the differential diagnosis.
Overexpression of miR169o, an Overlapping MicroRNA in Response to Both Nitrogen Limitation and Bacterial Infection, Promotes Nitrogen Use Efficiency and Susceptibility to Bacterial Blight in Rice (2018)

Limiting nitrogen (N) supply contributes to improved resistance to bacterial blight (BB) caused by Xanthomonas oryzae pv. oryzae (Xoo) in susceptible rice (Oryza sativa). To understand the regulatory roles of microRNAs (miRNAs) in this phenomenon, 63 differentially expressed overlapping miRNAs in response to Xoo infection and N limitation stress in rice were identified through deep RNA sequencing and stem-loop quantitative real-time PCR. Among these, miR169o was further assessed as a typical overlapping miRNA through the overexpression of the miR169o primary gene. Osa-miR169o-OX plants were taller, and had more biomass accumulation with significantly increased nitrate and total amino acid contents in roots than the wild type (WT). Transcript level assays showed that under different N supply conditions, miR169o oppositely regulated NRT2, and this is reduced under normal N supply conditions but remarkably induced under N-limiting stress. On the other hand, osa-miR169o-OX plants also displayed increased disease lesion lengths and reduced transcriptional levels of defense gene (PR1b, PR10a, PR10b and PAL) compared with the WT after inoculation with Xoo. In addition, miR169o impeded Xoo-mediated NRT transcription. Therefore, the overlapping miR169o contributes to increase N use efficiency and negatively regulates the resistance to BB in rice. Consistently, transient expression of NF-YA genes in rice protoplasts promoted the transcripts of PR genes and NRT2 genes, while it reduced the transcripts of NRT1 genes. Our results provide novel and additional insights into the co ordinated regulatory mechanisms of cross-talk between Xoo infection and N deficiency responses in rice.
Genetic uncoupling of the dsRNA‐binding and RNA cleavage activities of the Escherichia coli endoribonuclease RNase III — the effect of dsRNA binding on gene expression (1998)

RNase III, a double-stranded RNA-specific endonuclease, is proposed to be one of Escherichia coli's global regulators because of its ability to affect the expression of a large number of unrelated genes by influencing post-transcriptional control of mRNA stability or mRNA translational efficiency. Here, we describe the phenotypes of bacteria carrying point mutations in rnc, the gene encoding RNase III. The substrate recognition and RNA-processing properties of mutant proteins were analysed in vivo by measuring expression from known RNase III-modulated genes and in vitro from the proteins' binding and cleavage activities on known double-stranded RNA substrates. Our results show that although the point mutation rnc70 exhibited all the usual rnc null-like phenotypes, unlike other mutations, it was dominant over the wild-type allele. Multicopy expression of rnc70 could suppress a lethal phenotype of the wild-type rnc allele in a certain genetic background; it could also inhibit the RNase III-mediated activation of lambdaN gene translation by competing for the RNA-binding site of the wild-type endonuclease. The mutant protein failed to cleave the standard RNase III substrates in vitro but exhibited an affinity for double-stranded RNA when passed through poly(rI):poly(rC) columns. Filter binding and gel-shift assays with purified Rnc70 showed that the mutant protein binds to known RNase III mRNA substrates in a site-specific manner. In vitro processing reactions with purified enzyme and labelled RNA showed that the in vivo dominant effect of the mutant enzyme over the wild-type was not necessarily caused by formation of mixed dimers. Thus, the rnc70 mutation generates a mutant RNase III with impaired endonucleolytic activity but without blocking its ability to recognize and bind double-stranded RNA substrates.
Microwave tomography of extremities: 2. Functional fused imaging of flow reduction and simulated compartment syndrome (2011)

Medical imaging has recently expanded into the dual- or multi-modality fusion of anatomical and functional imaging modalities. This significantly improves the diagnostic power while simultaneously increasing the cost of already expensive medical devices or investigations and decreasing their mobility. We are introducing a novel imaging concept of four-dimensional (4D) microwave tomographic (MWT) functional imaging: three dimensional (3D) in the spatial domain plus one dimensional (1D) in the time, functional dynamic domain. Instead of a fusion of images obtained by different imaging modalities, 4D MWT fuses absolute anatomical images with dynamic, differential images of the same imaging technology. The approach was successively validated in animal experiments with short-term arterial flow reduction and a simulated compartment syndrome in an initial simplified experimental setting using a dedicated MWT system. The presented fused images are not perfect as MWT is a novel imaging modality at its early stage of the development and ways of reading reconstructed MWT images need to be further studied and understood. However, the reconstructed fused images present clear evidence that microwave tomography is an emerging imaging modality with great potentials for functional imaging.
Detection of Nitric Oxide and Nitrogen Dioxide with Photoluminescent Porous Silicon (1996)

The visible photoluminescence of porous Si is quenched by nitric oxide and nitrogen dioxide to detection limits of 1.4 × 10(-)(3) and 5.3 × 10(-)(5) Torr, respectively (corresponding to 2 ppm and 70 ppb). At analyte partial pressures in the low milliTorr range, the photoluminescence quenching is partially reversible; recovery from nitrogen oxide exposure occurs on a time scale of minutes. For both NO and NO(2), the reversible photoluminescence quenching response fits a Stern-Volmer kinetic model. At higher partial pressures, quenching deviates from Stern-Volmer kinetics and some permanent loss of photoluminescence intensity occurs due to oxidation of the porous Si surface. Photoluminescence from porous Si is not quenched by nitrous oxide or carbon dioxide and only slightly quenched by carbon monoxide and oxygen.
Multimedia, Multipoint Communications. (1998)

Abstract : This research project focused on two parallel, complementary research activities designed to address potential problems arising in the transmission of multimedia traffic to multiple parties over both nigh-speed wired and lower speed wireless communication networks of the future. The first addressed appropriate flow/congestion control in this multicast environment, and specifically the design of algorithms to control the flow of traffic between a source and multiple receivers, either fixed or mobile, located at possibly different distances from the source, so that the receivers can each handle the traffic flow, and yet provide as high a throughput as possible with queueing delays constrained to acceptable values. The second activity addressed the efficient transmission of digital, standards-based video (MPEG-1/MPEG-2) in this networking environment. To mitigate the highly variable nature of network conditions in terms of available bandwidth and delay, we investigated algorithms that combined rate shaping (on-the-fly modification of the video bit rate) and flow control to maximize the received video quality. To ensure that the video traffic is a fair and equitable user of the network, we used TCP flow control but no error control, so that video competes fairly for resources with traditional types of traffic (which are predominantly TCP-based).
Convective blueshifts in the solar atmosphere: III. High-accuracy observations of spectral lines in the visible (2019)

Convective motions in the solar atmosphere cause spectral lines to become asymmetric and shifted in wavelength. For photospheric lines, this differential Doppler shift varies from the solar disk center to the limb. Precise and comprehensive observations of the convective blueshift and its center-to-limb variation improve our understanding of the atmospheric hydrodynamics and ensuing line formation, and provide the basis to refine 3D models of the solar atmosphere. We performed systematical spectroscopic measurements of the convective blueshift of the quiet Sun with the Laser Absolute Reference Spectrograph (LARS) at the German Vacuum Tower Telescope. The spatial scanning of the solar disk covered four radial (meridional and equatorial) axes. The high-resolution spectra of 26 photospheric to chromospheric lines in the visible range were calibrated with a laser frequency comb to absolute wavelengths at the 1m/s accuracy. Applying ephemeris and reference corrections, the bisector analysis provided line asymmetries and Doppler shifts with an uncertainty of only few m/s. To allow for a comparison with other observations, we convolved the results to lower spectral resolutions. Typically, a blueshifted "C"-shaped curve at disk center transforms into a less blueshifted "\"-shape toward the solar limb. The comparison of all lines reveals the systematic dependence of the convective blueshift on the line depth. Synthetic models yield considerable deviations from the observed center-to-limb variation. The obtained Doppler shifts of the quiet Sun can serve as an absolute reference for other observations, the relative calibration of Dopplergrams, and the necessary refinement of atmospheric models. Based on this, the development of high-precision models of stellar surface convection will advance the detection of (potentially habitable) exoplanets by radial velocity measurements.
Redox Polymers for Energy Devices (2018)

Redox-active polymers are characterized by a dense population of the electron-releasing and -gaining site that allows efficient redox-gradient driven electron- or charge-transport and -storage throughout the polymer layers via self-exchanging reactions. The redox sites are robust nitroxide and phenoxyl, quinones, viologen, etc. The polymers provide surprisingly high current density beyond 1 A/cm2, to yield very rapid charging, high energy density storage and cyclability in the electrode performance. Organic-based, high-power and flexible batteries are the application examples. A polymer-based hydrogen carrier utilizing the reversible redox or hydrogenation is also introduced.
Third- and Fifth-Order Nonlinear Optical Response of a TICT/Stilbene Hybrid Chromophore (2020)

Twisted intramolecular charge transfer (TICT) chromophores exhibit a promising third-order nonlinear optical (NLO) response, γ, which is potentially useful for all-optical switching. Here we explore the third- and fifth-order NLO response of a newly synthesized chromophore, TMC-3′, which incorporates both stilbene and TICT motifs with optical function. Solution Z-scan measurements in CH2Cl2 reveal modest two-photon absorptions (2PA) at 1100 and 800 nm (σ2PA > 80 GM), and two contributions to the nonlinear refraction. The first component is attributed to the third-order bound-electronic response, while the second is assigned to a fifth-order process involving 2PA induced excited state refraction (2PA-ESR). Quantum computation suggests that the differences between the present work and previous studies lie primarily in the addition of the stilbene related states, as well as the increase in ground state dipole moment. This work yields insight into the third- and fifth-order NLO response of TICT chromophores and demonstrates that subtle structural modifications significantly impact their functionality.
Extrusion processing of TPO nanocomposites (2004)

Abstract Nanocomposites are a class of materials that use molecular‐sized particles for reinforcing the polymer matrix. These materials blend an organoclay with polymer to produce a composite with physical and mechanical properties equal to or better than their conventionally filled counterparts but at lower filler loadings. Occasionally, when the processing conditions are not optimized, compaction of the filler materials can occur. This agglomeration of the filler can affect the final properties of the composite by lowering the effective filler concentration and by the creation of stress risers around these agglomerates. This paper addresses the role of extrusion processing as it relates to the dispersion of the organoclay filler. Polym. Eng. Sci. 44:1036–1045, 2004. © 2004 Society of Plastics Engineers.
Emerging New Trends in Hybrid Vehicle Localization Systems (2012)

Over the last decade, vehicle localization has been attracting attention in a wide range of applications. A number of localization techniques have been developed to serve a variety of applications Al-Bayari & Sadoun (2005); Aono et al. (
A scalable MIMD volume rendering algorithm (2002)

Volume rendering is a compute intensive graphics algorithm with wide application. Researchers have sought to speed it up using parallel computers. The algorithm distributes the data for storage efficiency, avoids bottlenecks, and scales to more processors than rays. The main contribution is explicit partitioning of the input volume for higher memory utilization, while retaining viewpoint freedom and speedup. The largest volumes processed on the MIMD (multiple instruction multiple data) machine (Proteus) are 512/spl times/512/spl times/128 voxels (32 Mbytes). Performance measurements show a speedup of 22 over sequential code on 32 Intel i860 processors. We have used no preprocessing or data dependent optimization. The efficiency results from nonconflicting communication, a permutation warp, that remains efficient with larger data sets, larger parallel machines, and high order filters showing scalability can be achieved through object space partitioning.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Theory and Application of Dissociative Electron Capture in Molecular Identification (2006)

The coupling of an electron monochromator (EM) to a mass spectrometer (MS) has created a new analytical technique, EM-MS, for the investigation of electrophilic compounds. This method provides a powerful tool for molecular identification of compounds contained in complex matrices, such as environmental samples. EM-MS expands the application and selectivity of traditional MS through the inclusion of a new dimension in the space of molecular characteristics--the electron resonance energy spectrum. However, before this tool can realize its full potential, it will be necessary to create a library of resonance energy scans from standards of the molecules for which EM-MS offers a practical means of detection. Here, an approach supplementing direct measurement with chemical inference and quantum scattering theory is presented to demonstrate the feasibility of directly calculating resonance energy spectra. This approach makes use of the symmetry of the transition-matrix element of the captured electron to discriminate between the spectra of isomers. As a way of validating this approach, the resonance values for twenty-five nitrated aromatic compounds were measured along with their relative abundance. Subsequently, the spectra for the isomers of nitrotoluene were shown to be consistent with the symmetry-based model. The initial success of this treatment suggests that it might be possible to predict negative ion resonances and thus create a library of EM-MS standards.
The effect of BMP-mimetic peptide tethering bioinks on the differentiation of dental pulp stem cells (DPSCs) in 3D bioprinted dental constructs (2020)

The goal of this study was to use 3D bioprinting technology to create a bioengineered dental construct containing human dental pulp stem cells (hDPSCs). To accomplish this, we first developed a novel bone morphogenetic protein (BMP) peptide-tethering bioink formulation and examined its rheological properties, its printability, and the structural stability of the bioprinted construct. Second, we evaluated the survival and differentiation of hDPSCs in the bioprinted dental construct by measuring cell viability, proliferation, and gene expression, as well as histological and immunofluorescent analyses. Our results showed that the peptide conjugation into the gelatin methacrylate-based bioink formulation was successfully performed. We determined that greater than 50% of the peptides remained in the bioprinted construct after three weeks in vitro cell culture. Human DPSC viability was >90% in the bioprinted constructs immediately after the printing process. Alizarin Red staining showed that the BMP peptide construct group exhibited the highest calcification as compared to the growth medium, osteogenic medium, and non-BMP peptide construct groups. In addition, immunofluorescent and quantitative reverse transcription-polymerase chain reaction analyses showed robust expression of dentin sialophosphoprotein and osteocalcin in the BMP peptide dental constructs. Together, these results strongly suggested that BMP peptide-tethering bioink could accelerate the differentiation of hDPSCs in 3D bioprinted dental constructs.
Direct Iodination of Aromatic Compounds with Iodine and Alumina-Supported Copper(II) Chloride or Sulfate (1992)

Abstract The iodination of aromatic compounds (polymethylbenzenes, alkyl phenyl ethers, and polynuclear aromatic hydrocarbons) with iodine in combination with copper(II) chloride or sulfate supported on alumina proceeds well under mild conditions to selectively give monoiodinated compounds in high yields.
Agelasine F from a Philippine Agelas sp. Sponge Exhibits in vitro Antituberculosis Activity (2000)

Marine sponge samples were collected in Baler, Aurora, Philippines, and extracts were tested for in vitro antituberculosis activity. An orange Agelas sp. sponge yielded the known compound, agelasine F, which inhibited some drug resistant strains of Mycobacterium tuberculosis in vitro at concentrations as low as 3.13 micrograms/ml. Activity against M. tuberculosis residing within macrophages required concentrations of 13-22 micrograms/ml which was below the IC50 for Vero cells (34 micrograms/ml).
Back to backtracking: controlling the ATMS (1986)

The ATMS (Assumption-Based Truth Maintenance System) provides a very general facility for all types of default reasoning. One of the principal advantages of the ATMS is that all of the possible (usually mutually inconsistent) solutions or partial solutions are directly available to the problem solver. By exploiting this capability of the ATMS, the problem solver can efficiently work on all solutions simultaneously and avoid the computational expense of backtracking. However, for some applications this ATMS capability is more of a hindrance than a help and some form of backtracking is necessary. This paper first outlines some of the reasons why backtracking is still necessary, and presents a powerful backtracking algorithm which we have implemented which backtracks more efficiently than other approaches.
Frequency tuning and pulse generation in a fiber laser with an intracavity semiconductor active filter (1993)

The authors demonstrate optical frequency tuning by direct electrical means as well as FM and AM mode-locking in an erbium-doped fiber laser with an intracavity distributed Bragg reflector active filter/modulator. They obtained a 6 nm discrete tuning range and pulses of 38 and 78 ps duration in AM and FM mode-locking, respectively.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Bicarbonate and urea kinetics modeling during hemodialysis and online postdilution hemodiafiltration. (2008)

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