gebhart/patrepeval huggingface dataset:
Simplified flexible-PON upstream transmission using pulse position modulation at ONU and DSP-enabled soft-combining at OLT for adaptive link budgets (2015)

We demonstrate a flexible modulation and detection scheme for upstream transmission in passive optical networks using pulse position modulation at optical network unit, facilitating burst-mode detection with automatic decision threshold tracking, and DSP-enabled soft-combining at optical line terminal. Adaptive receiver sensitivities of -33.1 dBm, -36.6 dBm and -38.3 dBm at a bit error ratio of 10(-4) are respectively achieved for 2.5 Gb/s, 1.25 Gb/s and 625 Mb/s after transmission over a 20-km standard single-mode fiber without any optical amplification.
Effect of Pad Surface Roughness on SiO2 Removal Rate in Chemical Mechanical Polishing with Ceria Slurry (2006)

The effect of pad surface roughness on SiO2 removal rate was investigated using four different slurries containing ceria (CeO2) powders of different crystallite sizes and mean particle sizes. A clear maximum was observed in the dependence of removal rate on pad surface roughness. The four ceria slurries showed a peak in blanket wafer removal rate against pad surface roughness Ra. The peak moved toward larger Ra values with decreasing ceria crystallite size. The removal rate was strongly influenced not only by pad surface roughness but also by the crystallite size of ceria in the slurry.
EXPERIMENTAL EVALUATION OF FUEL PREPARATION SYSTEMS FOR AN AUTOMOTIVE GAS TURBINE CATALYTIC COMBUSTOR (1977)

Spatial fuel distributions, degree of vaporization, pressure drop and air velocity profiles were measured. Three airblast injectors and an air-assist nozzle were tested. Air swirlers were used to improve the spatial fuel-air distribution. The work was done in a 12 cm tubular duct. Test conditions were: a pressure of 0.3 and 0.5 MPa, inlet air temperatures up to 800 K, air velocities of 10 20 m/s and fuel-air ratios up to 0.020. The fuel was Jet A. The best results were obtained with an airblast configuration that used multiple cones to provide high velocity air for atomization and also straightened the inlet airflow. With this configuration, uniform spatial fuel-air distributions were obtained with mixing lengths greater than 17.8 cm. In this length, vaporization of the fuel was 98.5 percent complete at an inlet air temperature of 700 K. The total pressure loss was 1.0 percent with a reference velocity of 20 m/s and 0.25 percent at 10m/s. The air velocity was uniform across the duct and no autoignition reactions were observed.
ChemInform Abstract: Enzyme‐Catalyzed Hydrolysis of 3,5‐cis‐Diacetoxy‐4‐trans‐benzyloxymethylcyclopentene and the Synthesis of Aristeromycin Precursors. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Renal Vein and Inferior Vena Cava Tumor Thrombus in Renal Cell Carcinoma (1992)

Renal cell carcinoma has a propensity to extend as tumor thrombus into the renal vein and inferior vena cava (IVC). The preoperative assessment for the presence and extent of renal vein and IVC tumor thrombus is important for planning appropriate surgical resection. Imaging procedures [CT, ultrasound (US), MR, venacavography] were correlated with surgical findings and pathology in 431 consecutive patients who had a radical nephrectomy for renal cell carcinoma. Ninety-nine (23%) patients had tumor thrombus extending at least into the main renal vein. Of these, 29 had tumor thrombus extending within the IVC. Patients were classified into two groups based on the surgical extent of tumor thrombus. Group A patients had no tumor thrombus or had tumor thrombus only in the renal vein proximal to the site of surgical ligation. Group B patients had tumor thrombus that extended to or beyond the distal renal vein at the site of surgical ligation. Forty-one patients had Group B tumor thrombus. Group B tumor thrombus was not seen in a renal cell carcinoma that was smaller than 4.5 cm. The sensitivity of CT for detecting Group B tumor thrombus was 79% and that of US was 68%. However, a much higher percentage of US examinations were technically indeterminate. In the patients who had either MR or venacavography, both imaging procedures were 100% sensitive for detecting group B tumor thrombus. Magnetic resonance imaging and venacavography appear to be the most sensitive means of identifying tumor thrombus.
Further Studies of the Spectroscopic Properties and Photochemistry of Binuclear Rhodium(I) Isocyanide Complexes (1979)

The position of the lowest allowed electronic transition (1a2u → 2a1g in D4h) in Rh2L42+ (L = binucleating isocyanide) depends on the rotameric configuration of the complex [553 nm in Rh2(bridge)42+ (eclipsed); 515 nm in Rh2(TM4-bridge)42+ (30° staggered)]; the Rh(I)-Rh(I) distances are 3.26 and 3.25 Å, respectively. Reaction of Rh2(bridge)42+ (or Rh22+) with H2 in dilute aqueous acidic solutions yields Rh4H24+ (λmax = 780 nm). The Rh4H24+ species also is produced by low-temperature (-60°C) irradiation (λ > 520 nm) of 6M HCl solution of HRh2Cl2+ (λmax = 578 nm). The possible role of Rh4H24+ as an intermediate in the H2-producing photoreaction of HRh2Cl2+ (HRh2Cl2+ Rh2Cl22+ + H2) is discussed.
Hot excited state management for long-lived blue phosphorescent organic light-emitting diodes (2017)

Since their introduction over 15 years ago, the operational lifetime of blue phosphorescent organic light-emitting diodes (PHOLEDs) has remained insufficient for their practical use in displays and lighting. Their short lifetime results from annihilation between high-energy excited states, producing energetically hot states (>6.0 eV) that lead to molecular dissociation. Here we introduce a strategy to avoid dissociative reactions by including a molecular hot excited state manager within the device emission layer. Hot excited states transfer to the manager and rapidly thermalize before damage is induced on the dopant or host. As a consequence, the managed blue PHOLED attains T80=334±5 h (time to 80% of the 1,000 cd m<sup>-2</sup> initial luminance) with a chromaticity coordinate of (0.16, 0.31), corresponding to 3.6±0.1 times improvement in a lifetime compared to conventional, unmanaged devices. To our knowledge, this significant improvement results in the longest lifetime for such a blue PHOLED.
High power ultrashort fiber laser system at 1.55 um (2016)

Ultrashort erbium fiber laser system is presented. Optical module is integrated in IPG standard rack and is ready to use. Pulses with energy up to 20 microjoules are obtained, whereas maximum pulse repetition rate is 2 MHz. One of the main features of the system is fast individual pulse energy modulation. Burst mode of several pulses with specified pulse energy is also supported.
A Triple Phase-Shift Based Control Method for RMS Current Minimization and Power Sharing Control of Input-Series Output-Parallel Dual Active Bridge Converter (2020)

High frequency modular power converters are increasingly becoming popular due to their small size and weight. Targeting the input-series and output-parallel (ISOP) dual active bridge (DAB) DC-DC converters, this paper proposes a control scheme based on optimal triple phase-shift (TPS) control for both power sharing control and RMS current minimization. This achieves balanced power transmission, even under mismatched leakage inductance of a DAB module of the ISOP. In order to obtain the optimal zones of operation for the converter, the RMS current was minimized using the Lagrange multiplier method to obtain the optimal duty cycles. The power balancing was added to compensate unbalanced power sharing for variations in model parameters or module shutdown. Analyses and simulation results through MATLAB/Simulink are presented to validate the proposed controller.
Pressure dependence of metal-insulator transition in perovskitesRNiO3(R=Eu, Y, Lu) (2010)

High-pressure experiments on the $R{\text{NiO}}_{3}$ perovskites with smaller rare-earth ${R}^{3+}$ ions complete our study of the crossover from itinerant to localized $e$-electron behavior associated with the low-spin $\text{Ni}(\text{III}):{t}^{6}{e}^{1}$ ion. By measuring second-sintered samples in a multianvil module, we have observed a clear anomaly of $\ensuremath{\rho}(T)$ at ${T}_{\text{IM}}$ and obtained the pressure dependence of ${T}_{\text{IM}}$ for the $R{\text{NiO}}_{3}$ ($R=\text{Eu}$, Y, Lu) that are different from the published data supporting a charge-ordering model. Instead, they are comparable to that for the orbital-ordering insulator ${\text{LaMnO}}_{3}$. Our distinct results show clearly that where the crossover is approached from the localized-electron side by increasing the orbital overlap integral, a cooperative Jahn-Teller distortion prevents charge transfer from molecular $e$ orbitals on strongly bonded ${\text{NiO}}_{6/2}$ clusters to more weakly bonded Ni(III) centers. However, where the crossover is approached from the itinerant-electron side as in the perovskite ${\text{CaFeO}}_{3}$, a disproportionation charge transfer may occur. In a separate experiment in which the powder samples were pressed in a Bridgman anvil device without a pressure medium, we have shown after releasing pressure that the samples were reduced. This irreversible effect should be distinguished from the hydrostatic-pressure effect on the physical properties of the $R{\text{NiO}}_{3}$ perovskites.
Corrigendum: Visible‐Light‐Driven Hydrogen Evolution Using Planarized Conjugated Polymer Photocatalysts (2018)

The authors regret that incorrect data was presented in Figure The corrected Figures and Table Hence, the trends observed between materials and the overall conclusions made in the Communication remain valid. The correct H 2 evolution rate for the most active polymer, P7,under visible light (> 420 nm) should be 37.3 mmol h 1 (1492 mmol g 1 h 1 ), not 92.0 mmol h 1 as initially reported. The apparent quantum yields at 420 nm for P1K, P6, and P7 should be corrected to 0.4 %(AE 0.1 %), 2.2 %(AE 0.2 %), and 7. 2% (AE 0.3 %), respectively.
Long term remissions with combined modality therapy for advanced Hodgkin's disease (1976)

A new treatment program for advanced Hodgkin's disease employing five-drug combination chemotherapy and low dose radiation to the sites of bulk disease (nodal or parenchymal) was designed in 1969. Eighty patients have now been treated, 60 of whom have achieved a complete remission. More significantly, only 5 of the 60 completed responders have relapsed with follow-up from 1-6 years. The cumulative survival at 5 years of patients entering complete remission is 92%. For those patients not sustaining a complete remission, it is 19% at 2 years. This program has resulted in substantially lower relapse rates than previously reported by other investigators, probably because of the administration of radiotherapy in the manner described. Hopefully, a significant number of these patients may be cured of their disease.
Plasmonic Optical Interference (2014)

Understanding optical interference is of great importance in fundamental and analytical optical design for next-generation personal, industrial, and military applications. So far, various researches have been performed for optical interference phenomena, but there have been no reports on plasmonic optical interference. Here, we report that optical interference could be effectively coupled with surface plasmons, resulting in enhanced optical absorption. We prepared a three-dimensional (3D) plasmonic nanostructure that consists of a plasmonic layer at the top, a nanoporous dielectric layer at the center, and a mirror layer at the bottom. The plasmonic layer mediates strong plasmonic absorption when the constructive interference pattern is matched with the plasmonic component. By tailoring the thickness of the dielectric layer, the strong plasmonic absorption can facilely be controlled and covers the full visible range. The plasmonic interference in the 3D nanostructure thus creates brilliant structural colors. We develop a design equation to determine the thickness of the dielectric layer in a 3D plasmonic nanostructure that could create the maximum absorption at a given wavelength. It is further demonstrated that the 3D plasmonic nanostructure can be realized on a flexible substrate. Our 3D plasmonic nanostructures will have a huge impact on the fields of optoelectronic systems, biochemical optical sensors, and spectral imaging.
Platelet-Derived Growth Factor Increases the In Vivo Activity of Phospholipase C-γ1 and Phospholipase C-γ2 (1991)

Upon binding to its cell surface receptor, platelet-derived growth factor (PDGF) causes the tyrosine phosphorylation of phospholipase C-gamma 1 (PLC-gamma 1) and stimulates the production of diacylglycerol and inositol 1,4,5-triphosphate. We showed that following stimulation by PDGF, rat-2 cells overexpressing PLC-gamma 1 display an increase in the levels of both tyrosine-phosphorylated PLC-gamma 1 and inositol phosphates compared with the parental rat-2 cells. This increased responsiveness to PDGF is a direct effect of PLC-gamma 1 overexpression, as a cell line expressing similar levels of an enzymatically inactive point mutant of PLC-gamma 1, PLC-gamma 1 335Q, did not show elevated inositol phosphate production in response to PDGF. Hematopoietic cells express PLC-gamma 2, a PLC isoform that is closely related to PLC-gamma 1. When rat-2 cells overexpressing PLC-gamma 2 were treated with PDGF, an increase in both the tyrosine phosphorylation and the in vivo activity of PLC-gamma 2 was observed. Aluminum fluoride (AIF4-), a universal activator of PLC linked to G-proteins, did not produce an increase in the levels of inositol phosphates in either of the overexpressing cell lines compared with parental rat-2 cells, demonstrating that PLC-gamma isoforms respond specifically to a receptor with tyrosine kinase activity.
A novel noninvasive approach for evaluating work of breathing indices in a developmental rat model using respiratory inductance plethysmography (2020)

Pulmonary function testing (PFT) is an important component for evaluating the outcome of experimental rodent models of respiratory diseases. Respiratory inductance plethysmography (RIP) provides a noninvasive method of PFT requiring minimal cooperation. RIP measures work of breathing (WOB) indices including phase angle (Ф), percent rib cage (RC %), breaths per minute (BPM), and labored breathing index (LBI) on an iPad. The aim of this study was to evaluate the utility of a recently developed research instrument, pneuRIP, for evaluation of WOB indices in a developmental rat model. Sprague Dawley rats (2 months old) were commercially acquired and anaesthetised with isoflurane. The pneuRIP system uses two elastic bands: one band (RC) placed around the rib cage under the upper armpit and another band (AB) around the abdomen. The typical thoracoabdominal motion (TAM) plot showed the abdomen and rib cage motion in synchrony. The plots of phase angle and LBI as a function of data point number showed that values were within the range. The distribution for phase angle and LBI was within a narrow range. pneuRIP testing provided instantaneous PFT results. This study demonstrated the utility of RIP as a rapid, noninvasive approach for evaluating treatment interventions in the rodent model.
A study of RF oscillator reliability in nanoscale CMOS (2013)

In this paper, we investigate the nature of oxide breakdown and stress-related degradation mechanisms in MOS transistors. The MOS breakdown time is quantified based on exponential-law and defect-generation models versus the oxide-thickness, gate area, temperature and voltage stress at a given cumulative failure. As a consequence, a design guide is presented to estimate the time dependent dielectric breakdown of any analog circuit. Based on reliability analysis, the lifetime of the recently introduced class-F oscillator is evaluated for both thin and thick oxide options in TSMC 65-nm CMOS process.
Supplementary Table 1 from Gene Expression Profiling in Uveal Melanoma Reveals Two Molecular Classes and Predicts Metastatic Death (2023)

Supplementary Table 1 from Gene Expression Profiling in Uveal Melanoma Reveals Two Molecular Classes and Predicts Metastatic Death
Research Resource: Interplay between the Genomic and Transcriptional Networks of Androgen Receptor and Estrogen Receptor α in Luminal Breast Cancer Cells (2012)

The cellular response to circulating sex steroids is more than the sum of individual hormone actions, instead representing an interplay between activities of the evolutionarily related steroid hormone receptors. An example of this interaction is in breast cancer, where the risk of dying from estrogen receptor-_ (ER_)-positive disease decreases approximately 4-fold when androgen receptor (AR) expression is high. In this study, we used chromatin immunoprecipitation sequencing (ChIP-seq) and microarray expression profiling to investigate the genomic and transcriptional cross talk between AR and ER_ signaling in a luminal breast cancer cell line model, ZR-75–1. Expression profiling demonstrated reciprocal interference between 5_-dihydrotestosterone (DHT)- and 17_-estradiol (E2)-induced transcriptional programs. Specifically, regulation of 26% of E2 and 15% of DHT target genes was significantly affected by cotreatment with the other hormone, in the majority of cases (78–83%) antagonistically. Pathway analysis suggested that DHT cotreatment, for example, depleted E2-regulated pathways in cell survival and proliferation. ChIP-seq identified substantial overlap between the steroid receptor cistromes in ZR-75–1 cells, with 10–13% of AR- and ER_-binding sites located within 10 kb of the other receptor. Enrichment of androgen response elements in ER_-binding sites and vice versa was revealed by motif analysis, and AR-binding sites were enriched about E2-responsive genes affected by DHT cotreatment. Targeted ChIP and expression analysis revealed locus-specific outcomes when AR and ER_ bind to the same DNA region. This work provides the first cistrome data for two steroid receptors in the same cell, insight into the antagonistic interplay between estrogens and androgens in luminal breast cancer, and an important resource for future work aimed at evaluating interrelated steroid receptors in different cellular systems.
85 W VECSEL output at 1270 nm with conversion efficiency of 59 % (2015)

We report on 1270 nm vertical-external-cavity surface-emitting lasers (VECSELs) with up to 59% conversion efficiency and maximum output power of 8.5 W (pump limited), at 5°C heat sink temperature. These VECSELs comprised wafer-fused gain mirrors in the flip-chip (thin-disk) heat dissipation scheme. The reflected pump light from the gain mirror surface was found to depend considerably on temperature and pump power.
Traitement endovasculaire d’un anévrisme et d’une sténose de l’artère rénale secondaires à une dysplasie fibromusculaire (2008)

Limited data are available regarding the optimal management of renal artery stenosis (RAS) with a coexisting renal artery aneurysm. We present a case of high-grade RAS treated successfully with a stent-graft deployment resulting in the exclusion of an associated aneurysm. This therapeutic approach induced the sustained normalization of the blood pressure without antihypertensive medication and the correction of biochemical abnormalities secondary to the RAS.
Increase of Cladding Pump Power Efficiency by a 19-Core Erbium Doped Fibre Amplifier (2017)

We demonstrate that a cladding pumped 19-core EDFA has 2.5-dB higher pump power efficiency than a cladding pumped 7-core EDFA. The 19-core EDFA with pump power of 22.8 W has gain of 12.7 dB and output power of 22.2 dBm.
The Cambridge History of China (1979)

The Cambridge History of China is one of the most far-reaching works of international scholarship ever undertaken, exploring the main developments in political, social, economic and intellectual life from the Ch'in empire to the present day. The contributors are specialists from the international community of sinological scholars. Many of the accounts break new ground; all are based on fresh research. The works are written not only with students and scholars but also with the general reader in mind. No knowledge of Chinese is assumed, though for readers of Chinese, proper and other names are identified with their characters in the index. Numerous maps and tables illustrate the text. Volume 3, covers the second great period of unified imperial power, 589–906, when China established herself as the centre of a wider cultural sphere, embracing Japan, Korea and Vietnam. It was an era in which there was a great deal of rapid social and economic change, and in which literature and the arts reached new heights of attainment.
Novel Role of Histone Deacetylase 11 (HDAC11) in Hematopoiesis (2012)

Abstract Abstract 4728 HDAC11 is the newest member of the HDAC family. The physiological role of this HDAC was mainly unknown until the discovery by our group that HDAC11 regulates IL-10 gene expression in immune cells in-vitro1. To better elucidate the role of HDAC11 in lineage differentiation and hematopoiesis, we have utilized an HDAC11 promoter-driven eGFP reporter transgenic mice (TgHDAC11-eGFP) which allow us to “visualize” dynamic changes in HDAC11 gene expression/transcriptional activity in immune cell compartments in vivo. Thus far, our data indicates that in hematopoietic stem cells (CD34+/Lin−), transcriptional activation of HDAC11, indicated by eGFP expression appears to be absent. Also, no eGFP expression is seen in the common lymphoid progenitors (CLP-CD34+/CD127+/CD117low/Lin−) and/or the common myeloid progenitors (CMP-CD34+/CD127−/CD117high/Lin−). In the T-cell compartment, transcriptional activation of HDAC11 increases from CD4−/CD8− T-cells to CD4+/CD8+ T-cells to single positive CD4+ and CD8+ T-cells. The expression of eGFP then decreases from naive to effector memory, but then increases again at terminal effector memory. Expression of eGFP, in the bone marrow moderately increase transitioning from Pro-B-cells (CD3−/CD200+/CD19low/CD43high), Pre-B-cells (CD3−/CD200+/CD19int/CD43int), and Immature (CD3−/CD200+/CD19high/CD43low) respectively. Interestingly eGFP expression doubles in the B-1 (CD3−/CD19+/CD200low/−) stage of differentiation in the periphery. Remarkably, eGFP expression appears to be at its highest in the plasma cell compartment of the bone marrow. A second murine model also available to us, HDAC11 knockout mice (HDAC11KO) were also utilize to confirm these findings. When compared to wild-type mice, HDAC11KO mice have increased B-1 B-cells and decreased plasma cells. In the myeloid compartment, using TgHDAC11-eGFP mice, expression of HDAC11 transcript in myeloblasts (CD34+/CD45dim/CD117+/Lin-) appears to be absent. However the expression increases to 50% in the promyelocytes (Side Scatter high/CD45dim/+/CD34−/CD117+) and to 98% in the granulocytes specifically Neutrophils (Side scatter high/CD45dim+/CD34−/CD117−/CD14−/Ly6Gbright+). Strikingly, monocytes (dendritic cells and macrophages) showed no expression of eGFP. Taken together, HDAC11 appears to be essential for proper B-cells and T-cell differentiation. It also seems to play a critical role in differentiation of granulocytes and monocytes. Therefore it is plausible that HDAC11 might function as a regulator of hematopoietic differentiation and expansion in vivo. A better understanding of this previously unknown role of HDAC11 in hematopoiesis might lead to targeted epigenetic therapies in hematological malignancies to influence the appropriate differentiation of these cells, and possibly augmenting the efficacy of immunotherapeutic approaches against malignancies. Disclosures: No relevant conflicts of interest to declare.