gebhart/patrepeval huggingface dataset:
Automated Construction Using Contour Crafting -- Applications on Earth and Beyond (2002)

Automated Construction Using Contour Crafting -- Applications on Earth and Beyond B. Khoshnevis, G. Bekey Pages 489-495 (2002 Proceedings of the 19th ISARC, Washington, USA, ISSN 2413-5844) Abstract: Although automation has advanced in manufacturing, the growth of automation in construction has been slow. Conventional methods of manufacturing automation do not lend themselves to construction of large structures with internal features. This may explain the slow rate of growth in construction automation. Contour Crafting (CC) is a recent layered fabrication technology that has a great potential in automated construction of whole structures as well as sub-components. Using this process, a single house or a colony of houses, each with possibly a different design, may be automatically constructed in a single run, imbedded in each house all the conduits for electrical, plumbing and air-conditioning. Our research also addresses the application of CC in building habitats on other planets. CC will most probably be one of the very few feasible approaches for building structures on other planets, such as Moon and Mars, which are being targeted for human colonization before the end of the new century. Keywords: Contour Crafting, housing construction, construction on other planets DOI: https://doi.org/10.22260/ISARC2002/0076 Download fulltext Download BibTex Download Endnote (RIS) TeX Import to Mendeley
In Vitro Activity of Sorgum Seed Antifungal Proteins against Grain Mold Pathogens (1997)

Several sorghum seed antifungal proteins (AFP), including sormatin, chitinase, glucanase, and ribosome-inhibiting protein (RIP), were extracted, partially purified using sequential ammonium sulfate precipitation, and eluted from a CM-Sephadex column using a linear salt gradient. Eluted fractions were tested for bioactivity against Fusarium moniliforme, Curvularia lunata, and Aspergillus flavus using hyphal rupture, hyphal extension, and spore germination methods. A fraction containing several AFPs was most inhibitory against F. moniliforme, C. lunata, and A. flavus. Spore germination of all three species was markedly inhibited by 360 ppm of AFPs. The inhibitory effects were not observed when the protein fraction was boiled, suggesting the involvement of undenatured proteins. Hyphal elongation inhibition was the least sensitive assay to detect the inhibitory effects of AFPs on these fungi. F. moniliforme exhibited hyphal rupture at the growing tip at protein levels as low as 70 ppm. C. lunata required higher protein levels (70−360 ppm) and ruptured only at hyphal tips. A. flavus did not exhibit hyphal disruption when treated with AFPs. Keywords: Antifungal proteins; sormatin; chitinase; glucanase; sorghum; Fusarium moniliforme; Curvularia lunata; bioactivity
Expression and biochemical properties of a protein serine/threonine phosphatase encoded by bacteriophage lambda. (1993)

The predicted amino acid sequence encoded by the open reading frame 221 (orf221) of bacteriophage lambda exhibited a high degree of similarity to the catalytic subunits of a variety of protein serine/threonine phosphatases belonging to PP1, PP2A, and PP2B groups. Cloning and expression of the orf221 gene in Escherichia coli provided direct evidence that the gene codes for a protein serine/threonine phosphatase. The single-subunit recombinant enzyme was purified in soluble form and shown to possess a unique repertoire of biochemical properties--e.g., an absolute requirement for Mn2+, resistance to okadaic acid, inhibitors 1 and 2, and ability to dephosphorylate casein, adenovirus E1A proteins, and the alpha subunit of phosphorylase kinase. No phosphotyrosine phosphatase activity was observed. Mutational and biochemical analyses identified the conserved residues 73-77 and Cys138 to be important for activity. The name PP-lambda is proposed for this unusual prokaryotic enzyme.
Afterglow Suppression and Non-Radiative Charge-Transfer in CsI:Tl,Sm (2008)

Suppression of afterglow in co-doped CsI:Tl is found to be an order of magnitude more effective in CsI:Tl, Sm than in CsI:Tl, Eu. Rate equations predict that deep electron traps introduced by co-doping with samarium effectively scavenge electrons from shallow traps associated with thallium, thus suppressing afterglow in the time domain of tens of milliseconds. In addition, combined radioluminescence and thermoluminescence experiments suggest that electrons released by samarium recombine non-radiatively with trapped holes, thus providing a mechanism for suppression of hysteresis. <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Ab</i> <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">initio</i> quantum chemistry calculations support the conclusion that non-radiative charge-transfer transitions in CsI:Tl, Sm are enabled by the presence of low-energy excited states of within the ground configuration.
An improved transmission line pulsing (TLP) setup for electrostatic discharge (ESD) testing in semiconductor devices and ICs (2002)

Transmission line pulsing (TLP) is a useful technique to characterize electrostatic discharge (ESD) events in semiconductor devices. The pulse waveforms generated by a typical TLP set-up, however, are often distorted and oscillatory. In this paper, a new and simple experimental set-up is developed to improve the shape of the TLP waveforms and thus to increase the effectiveness of the TLP technique. Experimental results obtained from the conventional and improved set-ups are presented and compared.
Blockchain-based Content Delivery Networks: Content Transparency Meets User Privacy (2019)

Blockchain is a merging technology for decentralized management and data security, which was first introduced as the core technology of cryptocurrency, e.g., Bitcoin. Since the first success in financial sector, blockchain has shown great potentials in various domains, e.g., internet of things and mobile networks. In this paper, we propose a novel blockchain-based architecture for content delivery networks (B-CDN), which exploits the advances of the blockchain technology to provide a decentralized and secure platform to connect content providers (CPs) with users. On one hand, the proposed B-CDN will leverage the registration and subscription of the users to different CPs, while guaranteeing the user privacy thanks to virtual identity provided by the blockchain network. On the other hand, the B-CDN creates a public immutable database of the requested contents (from all CPs), based on which each CP can better evaluate the user preference on its contents. The benefits of B-CDN are demonstrated via an edge-caching application, in which a feature-based caching algorithm is proposed for all CPs. The proposed caching algorithm is verified with the realistic Movielens dataset. A win-win relation between the CPs and users is observed, where the B-CDN improves user quality of experience and reduces cost of delivering content for the CPs.
R.F. Plasma CVD Of Diamond From Oxygen Containing Gases (1990)

A 13.56 MHz inductively coupled plasma system has been used to deposit diamond from CH<sub>4</sub>/O<sub>2</sub> in H<sub>2</sub>, CO in H2&apos; and CH<sub>4</sub>/CO<sub>2</sub> in H<sub>2</sub> plasmas. Depositions were made on substrates of silicon and quartz with surfaces modified by scratching, or coated with Diamond-Like Carbon (DLC), or left unmodified. The C atom to 0 atom ratio was systematically varied as well as the total concentration. Polycrystalline films, faceted particles and spherical particles were deposited. We found that a C:0 ratio of 1:1 with a total concentration between 2% and 3% in hydrogen resulted in large area polycrystalline films for the deposition parameters investigated.
Tocotrienol-treated MCF-7 human breast cancer cells show down-regulation of API5 and up-regulation of MIG6 genes. (2011)

Treatment of human MCF-7 cells with tocotrienol isomers causes the down-regulation of the API5 gene and up-regulation of the MIG6 gene and the differential expression of other genes reported to play a key role in breast cancer biology.
Performance measurement as a policy instrument (2016)

The rise of government by indicators, by figures may reveal a new wave of rationalization organized by the state in the classic Weberian sense. Contemporary forms of government are marked by the rise of indicators, measures and new metrics to compare, certify, codify and evaluate. In many countries, performance measurement has become one of the symbols of the transformation of governance. The paper aims to show how performance indicators are a particular type of policy instrument that increases competitive pressure within societies even if that cannot be analysed only in terms of neoliberalism.
Inhibition of ozone-induced SP-A oxidation by plant polyphenols (2006)

Surfactant protein-A (SP-A) is the best studied and most abundant of the protein components of lung surfactant and plays an important role in host defense of the lung. It has been shown that ozone-induced oxidation of SP-A protein changes its functional and biochemical properties. In the present study, eight plant polyphenols (three flavonoids, three hydroxycinnamic acids, and two hydroxybenzoic acids) known as strong antioxidants, were tested for their ability to inhibit ozone-induced SP-A oxidation as a mechanism for chemoprevention against lung damage. SP-A isolated from alveolar proteinosis patients was exposed to ozone (1 ppm) for 4 h. The flavonoids protected SP-A from oxidation in a dose dependent manner. ( - )-Epicatechin was the most potent flavonoid and exhibited inhibition of ozone-induced formation of carbonyls by 35% at a concentration as low as 5 microM. Hydroxybenzoic acids inhibited SP-A oxidation in a dose-dependent manner although they were less potent than flavonoids. On the other hand, hydroxycinnamic acids exhibited a different inhibitory pattern. Inhibition was observed only at medium concentrations. The results indicate that inhibition of SP-A oxidation by plant polyphenols may be a mechanism accounting for the protective activity of natural antioxidants against the effects of ozone exposure on lungs.
VelB/VeA/LaeA Complex CoordinatesLight Signal with Fungal Developmentand Secondary Metabolism (2008)

Differentiation and secondary metabolism are correlated processes in fungi that respond to light. In Aspergillus nidulans , light inhibits sexual reproduction as well as secondary metabolism. We identified the heterotrimeric velvet complex VelB/VeA/LaeA connecting light-responding developmental regulation and control of secondary metabolism. VeA, which is primarily expressed in the dark, physically interacts with VelB, which is expressed during sexual development. VeA bridges VelB to the nuclear master regulator of secondary metabolism, LaeA. Deletion of either velB or veA results in defects in both sexual fruiting-body formation and the production of secondary metabolites.
Linear DNA amplicons as a novel cancer vaccine strategy (2022)

These results strongly support the further exploration of the use of PCR-based amplicons as an innovative immunotherapeutic approach to cancer treatment.
Loss of Consciousness Is Associated with Stabilization of Cortical Activity (2015)

What distinguishes brain activity during consciousness from that observed during unconsciousness? Answering this question has proven difficult because neither consciousness nor lack thereof have universal signatures in terms of most specific features of brain activity. For instance, different anesthetics induce different patterns of brain activity. We demonstrate that loss of consciousness is universally and reliably associated with stabilization of cortical dynamics regardless of the specific activity characteristics. To give an analogy, our analysis suggests that loss of consciousness is akin to depressing the damper pedal on the piano, which makes the sounds dissipate quicker regardless of the specific melody being played. This approach may prove useful in detecting consciousness on the basis of brain activity under anesthesia and other settings.
Berichtigung: The Structural Fate of Individual Multicomponent Metal‐Oxide Nanoparticles in Polymer Nanoreactors (2018)

Diese Zuschrift enthält fehlerhafte Beschriftungen an den horizontalen Achsen der EDS-Spektren in den Abbildungen 1 D, 2 B, 2 E und 3 B (EDS = energiedispersive Röntgen-Spektroskopie). Die korrekte Achsenbeschriftung lautet “Energy (keV)”. Dieses Versehen hat keine Auswirkungen auf die Ergebnisse und Schlussfolgerungen der Zuschrift. Mit dieser Berichtigung werden außerdem revidierte Hintergrundinformationen zugänglich gemacht. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Medium-Voltage Converter Solution With Modular Multilevel Structure and Decentralized Energy Storage Integration for High-Power Wind Turbines (2021)

As the penetration of renewable energy generation increases, the importance of energy storage systems becomes evident since these systems can contribute for the preservation of the power system stability. Wind turbine owners can also benefit from having energy storage systems as they can increase their revenues. The fast growth of wind turbine power ratings will eventually lead to the requirement of higher voltage levels as well. Proper power electronic converters will be required to drive these systems. Converters with a modular multilevel structure are considered the state-of-the-art solution for high-power applications. These topologies allow for a flexible integration of energy storage systems in both centralized and decentralized ways. This article presents a new converter solution with a modular multilevel structure and decentralized energy storage integration suitable to drive high-power medium-voltage wind turbines. This converter presents important structural and control characteristics that allows for a straightforward integration of an energy storage system in such a way that the wind turbine driven by it can operate with high flexibility and in a dispatchable fashion, benefiting both the power system operator and the wind-power-plant owner.
CCDC 135797: Experimental Crystal Structure Determination (1999)

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.
Cerebellar degeneration-related antigen: a highly conserved neuroectodermal marker mapped to chromosomes X in human and mouse. (1990)

Cerebellar degeneration-related antigen (designated CDR34) was previously cloned by antibody screening of a cDNA library and was shown to be one of the target molecules recognized by autoantibodies in patients with paraneoplastic cerebellar degeneration. This molecule is distinctive in that it contains a tandem hexapeptide repetitive structure, presumably the basis for its high immunogenicity. In this study, we cloned the human CDR34 gene and proved that the entire repetitive sequence is encoded by a single exon without introns. We also showed that the nucleotide repeats are preserved only in the protein-coding sequences, suggesting evolutionary constraint in this region of the gene. Corresponding mouse cDNA clones were also isolated, which encoded a larger molecule with very similar hexapeptide repeating units. Comparison of the human and mouse repeats revealed a highly conserved Glu-Asp core in each unit, implicating the functional significance of this motif. Chromosomal mapping by somatic cell hybrid analysis mapped CDR34 to both human and mouse chromosomes X, and in situ hybridization further assigned CDR34 to human Xq24-q27.
Statistical characterization of very low frequency communication channels at ocean basin-scales (2006)

The bit rate for incoherent communication is estimated for low frequency sounds (75 Hz, 0.03 s resolution) transmitted 3115 km between a bottom-mounted source and a towed array. A model for short term fluctuations of sound agrees with measurements without tuning the model to the data. In particular, measured and modeled probability distributions for multipath coherence time and amplitude fluctuations are similar. Temporal evolution of the oceanographic component of the model is governed by the linear dispersion relation for internal gravity waves. The acoustic component of the model is based on the sound-speed insensitive parabolic approximation. This is the third attempt to use the model to predict short-term acoustic fluctuations at basin-scales. All three attempts yielded results similar to measurements. If further comparisons between the model and data are successful, the model could be used to design and implement low frequency communication systems. A simulation yields 4 bits per second for a Benthos modem using an incoherent communication scheme via frequency shift keying
Comparison of Macintosh, McCoy, and Glidescope video laryngoscope for intubation in morbidly obese patients: Randomized controlled trial (2018)

To conclude, GVL takes longer TTI with no added advantage in IDS and hemodynamic response to intubation in morbidly obese patients. McCoy is only as effective as Macintosh and hence Macintosh laryngoscope should be laryngoscope of choice due to its widespread availability and familiarity.
Synthesis of Supported Planar Iron Oxide Nanoparticles and Their Chemo- and Stereoselectivity for Hydrogenation of Alkynes (2017)

Nature uses enzymes to dissociate and transfer H2 by combining Fe2+ and H+ acceptor/donor catalytic active sites. Following a biomimetic approach, it is reported here that very small planar Fe2,3+ oxide nanoparticles (2.0 ± 0.5 nm) supported on slightly acidic inorganic oxides (nanocrystalline TiO2, ZrO2, ZnO) act as bifunctional catalysts to dissociate and transfer H2 to alkynes chemo- and stereoselectively. This catalyst is synthesized by oxidative dispersion of Fe0 nanoparticles at the isoelectronic point of the support. The resulting Fe2+,3+ solid catalyzes not only, in batch, the semihydrogenation of different alkynes with good yields but also the removal of acetylene from ethylene streams with >99.9% conversion and selectivity. These efficient and robust non-noble-metal catalysts, alternative to existing industrial technologies based on Pd, constitute a step forward toward the design of fully sustainable and nontoxic selective hydrogenation solid catalysts.
Thermodynamic Modeling of a Solid Oxide Fuel Cell to Couple with an Existing Gas Turbine Engine Model (2004)

The Controls and Dynamics Technology Branch at NASA Glenn Research Center are interested in combining a solid oxide fuel cell (SOFC) to operate in conjunction with a gas turbine engine. A detailed engine model currently exists in the Matlab/Simulink environment. The idea is to incorporate a SOFC model within the turbine engine simulation and observe the hybrid system's performance. The fuel cell will be heated to its appropriate operating condition by the engine s combustor. Once the fuel cell is operating at its steady-state temperature, the gas burner will back down slowly until the engine is fully operating on the hot gases exhausted from the SOFC. The SOFC code is based on a steady-state model developed by The U.S. Department of Energy (DOE). In its current form, the DOE SOFC model exists in Microsoft Excel and uses Visual Basics to create an I-V (current-voltage) profile. For the project's application, the main issue with this model is that the gas path flow and fuel flow temperatures are used as input parameters instead of outputs. The objective is to create a SOFC model based on the DOE model that inputs the fuel cells flow rates and outputs temperature of the flow streams; therefore, creating a temperature profile as a function of fuel flow rate. This will be done by applying the First Law of Thermodynamics for a flow system to the fuel cell. Validation of this model will be done in two procedures. First, for a given flow rate the exit stream temperature will be calculated and compared to DOE SOFC temperature as a point comparison. Next, an I-V curve and temperature curve will be generated where the I-V curve will be compared with the DOE SOFC I-V curve. Matching I-V curves will suggest validation of the temperature curve because voltage is a function of temperature. Once the temperature profile is created and validated, the model will then be placed into the turbine engine simulation for system analysis.
Durability of Peginterferon Alfa-2B Treatment at 5 Years in Patients With Hepatitis B E Antigen–Positive Chronic Hepatitis B (2010)

Peginterferon has high durability in HBeAg-positive chronic hepatitis B patients with end-of-treatment virologic response.
A hybrid inverse approach applied to the design of lumped-element RF coils (1999)

A combination of inverse procedures is employed in the design of radio-frequency (RF) coils with specific examples in, but not restricted to, magnetic resonance imaging. The first inverse procedure is the use of functional methods for the optimization of coil characteristics subject to restrictions on the field behavior. Continuous current distributions are derived from analysis of the fields they are required to produce. To make use of these distributions at a desired frequency, the method of moments is applied as a second inverse procedure to a discretized version of the current distribution. The advantage of this hybrid technique is that it provides a computational algorithm for optimization of feeding, tuning, impedance matching and other aspects of RF coil design. A prototype RF coil has been built using the engineering values predicted by the theory. Experimental results including images acquired from the prototype coil are presented.
A Novel Compact Reconfigurable Quad-band Power Amplifier Employing RF-MEMS Switches (2006)

A new reconfigurable multi-band power amplifier (PA) is presented. The newly proposed band-switchable matching network (MN) with a reconfigurable stub makes the multi-band PA compact. The MN employs RF-MEMS (micro-electro-mechanical systems) switches to change the operation band of the PA. According to the proposed scheme, a 0.9, 1.5, 1.9, and 2.5-GHz quad-band PA was designed and fabricated. The fabricated 1W-class PA achieved high output power and high power added efficiency as expected in each band. The results show that the reconfigurable PA contributes to future mobile terminals
Radiochemistry of Therapeutic Radionuclides (2018)

This chapter discusses the extension of the technique fromγ-emitters to particulate-emitting radionuclides for use in radioimmunotherapy (RAIT). It presents the advantages of usingα-particle-emitting radionuclides for RAIT. The use of monoclonal antibodies (MoAbs) as targeting vectors for use in radioimmunoscintigraphy is becoming an established clinical procedure. The direct radioiodination of proteins, including MoAbs and their fragments whereby the iodonium ion adds to protein tyrosine residues in the position ortho to the hydroxyl group in the aromatic ring. Unfortunately, yttrium (Y) is an element with great avidity for cortical bone, and unbound metal will quickly localize in the bone, which for RAIT with Y results in unacceptable radiotoxicity. Radium has interesting properties for RAIT since it is an α-emittting radionuclide with an 11.4-d half-life. Direct labeling of antibodies with astatine using electrophilic addition to tyrosine residues results in a carbon-astatine bond which is not sufficiently stable for RAIT purposes.