gebhart/patrepeval huggingface dataset:
Characterisations of the “mixed” small gain and passivity property for linear systems in discrete time (2013)

Characterisations of “mixed” systems are presented in a discrete-time setting. First, a feedback stability result based on the Nyquist stability theorem is presented. Second, an eigenvalue-based characterisation of “mixed” systems based on their state-space data is derived. The results are analogous to previous results presented for the continuous-time case and provide a foundation for further study concerning the discretisation of “mixed” systems.
An Aggregate Cluster‐Dispersed Electrolyte Guides the Uniform Nucleation and Growth of Lithium at Lithium Metal Anodes (2018)

Abstract Rechargeable lithium metal battery technology is widely recognized as being a suitable candidate for replacing lithium ion batteries. A critical barrier preventing its application to electrical storage systems is that lithium grows irregularly, which is the fundamental cause of poor characteristics during a battery‘s lifetime, and also causes safety concerns. There are two reasons for the irregular growth of lithium: lithium prefers to nucleate on specific surfaces; subsequently, the lithium atoms grow rapidly from any protrusions. To suppress such irregularities in electroplating, we combined two approaches; applying a coating of lithiophilic metal to a substrate that would otherwise attract the nucleation of lithium, and using an electrolyte in which aggregate clusters are dispersed, with strongly solvated ionic liquids enclosed by another solvent such as a hydrofluoroether. Together, these are intended to guide the uniform nucleation and growth of lithium. By tuning the combination of the two approaches, it was concept proven that lithium would nucleate and grow more uniformly than on a pristine Cu or Ni substrate.
Cementless total hip replacement without femoral osteotomy in patients with severe developmental dysplasia of the hip (2014)

We describe the clinical and radiological results of cementless primary total hip replacement (THR) in 25 patients (18 women and seven men; 30 THRs) with severe developmental dysplasia of the hip (DDH). Their mean age at surgery was 47 years (23 to 89). In all, 21 hips had Crowe type III dysplasia and nine had Crowe type IV. Cementless acetabular components with standard polyethylene liners were introduced as close to the level of the true acetabulum as possible. The modular cementless S-ROM femoral component was used with a low resection of the femoral neck. A total of 21 patients (25 THRs) were available for review at a mean follow-up of 18.7 years (15.8 to 21.8). The mean modified Harris hip score improved from 46 points pre-operatively to 90 at final follow up (p < 0.001). A total of 15 patients (17 THRs; 57%) underwent revision of the acetabular component at a mean of 14.6 years (7 to 20.8), all for osteolysis. Two patients (two THRs) had symptomatic loosening. No patient underwent femoral revision. Survival with revision of either component for any indication was 81% at 15 years (95% CI 60.1 to 92.3), with 21 patients at risk. This technique may reduce the need for femoral osteotomy in severe DDH, while providing a good long-term functional result.
Signal slope modulation method for high data transfer rates and reducing wiring density in high-speed digital systems (2017)

This paper presents a novel method of transferring data using a signal slope modulation method in high-speed digital systems. For the first time, this paper demonstrates that this signal slope modulation technique can be used for transferring high data per trace as well as for reducing wiring density in packages significantly. The unique combination of serial bus and parallel bus attributes of this method allows higher bit transfer rates, lower clock speeds, and lower trace and wiring counts.
4K Uncompressed Streaming over Multicast-capable 80 (8λ × 10) Gbps Colored Optical Packet Switching Network using SOA Switch and Stacked OC-Label Processing (2009)

We demonstrate a field trial of 4K uncompressed streaming over multicast-capable 80 (8λ × 10) Gbps colored optical packet switching network using SOA based broadcast-and-select switch and stacked optical-code label processing.
SURGERY FOR MOVEMENT DISORDERS (2008)

Movement disorders, such as Parkinson's disease, tremor, and dystonia, are among the most common neurological conditions and affect millions of patients. Although medications are the mainstay of therapy for movement disorders, neurosurgery has played an important role in their management for the past 50 years. Surgery is now a viable and safe option for patients with medically intractable Parkinson's disease, essential tremor, and dystonia. In this article, we provide a review of the history, neurocircuitry, indication, technical aspects, outcomes, complications, and emerging neurosurgical approaches for the treatment of movement disorders.
Enhancement of Thermal Stability Using Ferromagnetically Coupled Synthetic Free Layers in MgO-Based Magnetic Tunnel Junctions (2010)

Very high thermal stability ¿ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> was demonstrated in MgO-based magnetic tunnel junctions (MTJs) with CoFeB/Ru/CoFeB ferromagnetically coupled synthetic free layers (F-coupled Sy). Samples had a structure of underlayer/PtMn(15)/CoFe(2.5)/Ru(0.85)/CoFeB(3)/MgO(1)/F-coupled Sy/Ta(5)/Ru(7), where F-coupled Sy was CoFeB(2)/Ru(1.5)/CoFeB(d <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">CoFeB</sub> = 1-4 (nm unit). The MTJs were elliptical with approximate dimensions of 60 nm × 170 nm. Resistance-field (R - H) loops were measured repeatedly; the H-dependence of switching probability P <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">SW</sub> was observed. From the distribution of switching field H <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">C</sub> , thermal stability factor ¿ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> was evaluated based on the Sharrock equation. The ¿ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> values increased concomitantly with increasing thickness of the upper CoFeB layer d <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">CoFeB</sub> . We obtained very large ¿ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> values of about 248 when d <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">CoFeB</sub> = 4 nm. Such a large ¿ <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0</sub> originates in enhanced shape magnetic anisotropy in the F-coupled Sy. The shape anisotropy is lost because of the low effective magnetization if the magnetizations are coupled antiferromagnetically. The F-coupled Sy with a thicker upper magnetic layer is suitable for use in nonvolatile memory cells in magnetoresistive random access memory.
A highly solvated zinc(II) tetrakis(pentafluorophenyl)-β-octabromoporphyrin (1993)

, 19-dodecaene }zinc( II) (carbon tetrachloride, o-dichlorobenzene, acetone, methanol, water solvate) has a large tetrahedral distortion, with the Br atoms as much as t Contribution No. 8622.
Skeletal, cardiac and tongue muscle pathology, defective retinal transmission, and neuronal migration defects in the Largemyd mouse defines a natural model for glycosylation-deficient muscle - eye - brain disorders (2002)

We have recently shown that a deletion in the Large gene, encoding a putative glycosyltransferase, is the molecular defect underlying the myodystrophy (previously myd; now Large(myd)) mouse. Here we show that the muscular dystrophy phenotype is not confined to skeletal muscle, but is also present in the heart and tongue. Immunohistochemistry indicates disruption of the dystrophin-associated glycoprotein complex (DGC) in skeletal and cardiac muscle. Quantitative western blotting shows a general increase in the expression of DGC proteins and of dysferlin and caveolin-3 in mutant skeletal muscle. In contrast, the expression of DGC proteins is reduced in cardiac muscle. Overlay assays show loss of laminin binding by alpha-dystroglycan in Large(myd) skeletal and cardiac muscle and in brain. We also show that the phenotype of Large(myd) mice is not restricted to muscular dystrophy, but also includes ophthalmic and central nervous system (CNS) defects. Electroretinograms of homozygous mutant mice show gross abnormalities of b-wave characteristics, indicative of a complex defect in retinal transmission. The laminar architecture of the cortices of the cerebrum and the cerebellum is disturbed, indicating defective neuronal migration. Thus, the phenotype of the Large(myd) mouse shows similarities to the heterogeneous group of human muscle eye brain diseases characterized by severe congenital muscular dystrophy, eye abnormalities and CNS neuronal migration defects. These diseases include Fukuyama-type muscular dystrophy and muscle-eye-brain disease, both of which are also due to mutations in predicted glycosylation enzymes. Therefore, the Large(myd) mouse represents an important animal model for studying the function of glycosylation in muscle, brain and retina.
Influence of interferons corneal angiogenesis induced by basic fibroblast growth factor and lipopolysaccharide (1993)

A controlled and reproducible angiogenic stimulus was induced in the rabbit cornea by Elvax-40 implants sequestering either 500 ng of lipopolysaccharide (LPS) or 500 ng of basic fibroblast growth factor (bFGF). The effect of IFNα and IFN(β) on angiogenesis was studied by inserting implants sequestering 500 ng of these cytokines (approximately 10(4) Units/implant) adjacent to the LPS or bFGF implants. Interferon-α or γ did not inhibit the bFGF-induced angiogenesis, and in most of these experiments an enhancing effect was observed. This enhancement was not statistically significant. The LPS-induced angiogenesis, however, was slightly inhibited in the presence of either interferon-α or γ but these differences were not statistically significant with p=0.1 only. Both cytokines were non angiogenic and there was no detectable difference between them regarding their effect on the angiogenic process induced by either bFGF or LPS.
A comparison of theoretical and empirical reflection coefficients for typical exterior wall surfaces in a mobile radio environment (1996)

This paper presents microwave reflection coefficient measurements at 1.9 GHz and 4.0 GHz for a variety of typical smooth and rough exterior building surfaces. The measured test surfaces include walls composed of limestone blocks, glass, and brick. Reflection coefficients were measured by resolving individual reflected signal components temporally and spatially, using a spread-spectrum sliding correlation system with directional antennas. Measured reflection coefficients are compared to theoretical Fresnel reflection coefficients, applying Gaussian rough surface scattering corrections where applicable. Comparisons of theoretical calculations and measured test cases reveal that Fresnel reflection coefficients adequately predict the reflective properties of the glass and brick wall surfaces. The rough limestone block wall reflection measurements are shown to be bounded by the predictions using the Fresnel reflection coefficients for a smooth surface and the modified reflection coefficients using the Gaussian rough surface correction factors. A simple, but effective, reflection model for rough surfaces is proposed, which is in good agreement with propagation measurements at 1.9 GHz and 4 GHz for both vertical and horizontal antenna polarizations. These reflection coefficient models can be directly applied to the estimation of multipath signal strength in ray tracing algorithms for propagation prediction.
Clostridium difficileToxin A Alters In Vitro–Adherent Neutrophil Morphology and Function (2002)

The effects of purified toxin A in vitro on the shape and function of polymorphonuclear leukocytes (PMNL) were examined. Toxin A induced changes in adherent PMNL shape from a compact spherical or pyramidal shape to a thin and rope-like shape. This change in shape was accompanied by rearrangement of the F-actin cytoskeleton into aggregates. Toxin A-treated PMNL exhibited increased adherence and expressed less L-selectin and more Mac-1, compared with untreated PMNL. In contrast to these proinflammatory actions, toxin A impaired both directed and non-directed PMNL migration in response to N-formylmethionylleucylphenylalanine. In addition, toxin A decreased the oxidative activity of adherent PMNL stimulated by recombinant human tumor necrosis factor-alpha. These effects could be explained by toxin A-induced glucosylation of the signaling small-size guanine 5'-triphosphate-binding proteins of the Rho family in human PMNL.
Stokes Parameters and Hybridization of Optical Modes in Long-Wavelength Vertical-Cavity Surface-Emitting Lasers (VCSELs) (2014)

The polarization of the beam emitted from long-wavelength VCSELs is characterized with the Stokes parameters. Stable optical modes are discovered, with a polarization that differs from the linear case. Results are explained by hybridization of the VCSEL modes and a negative line width enhancement factor.
Partial Spectral Loss Concealment in Transform Coders (2006)

A novel error concealment technique for partial spectral loss in transform coders is presented. Based on amplitude and phase inter- and intra-frame correlations, an algorithm for missing spectral coefficient restoration is derived. The algorithm restores the missing spectral coefficients by predicting the amplitude using energy matching and the phase using group delay conservation principles. Results from listening tests illustrate the performance of the proposed algorithm.
Supplementary Figure 5 from Therapeutic and Prophylactic Antitumor Activity of an Oral Inhibitor of Fucosylation in Spontaneous Mammary Cancers (2023)

&lt;p&gt;Effect of 2FF-treatment on (A) Tumor volume (Mean {plus minus} SEM) over days since implant for mice treated with IgG2b (open circle), anti-CD8 (diamond), 20mM 2FF+IgG2b (closed circle), or 20mM 2FF+anti-CD8 (triangle), n=5 per group; and (B) Tumor volume (Mean {plus minus} SEM) over days since implant for mice treated with IgG2b (open circle), anti-NK (diamond), 20mM 2FF+IgG2b (closed circle), or 20mM 2FF+anti-NK (triangle), n=5 per group ****p&lt;0.0001.&lt;/p&gt;
An open-access database and analysis tool for perovskite solar cells based on the FAIR data principles (2021)

Abstract Large datasets are now ubiquitous as technology enables higher-throughput experiments, but rarely can a research field truly benefit from the research data generated due to inconsistent formatting, undocumented storage or improper dissemination. Here we extract all the meaningful device data from peer-reviewed papers on metal-halide perovskite solar cells published so far and make them available in a database. We collect data from over 42,400 photovoltaic devices with up to 100 parameters per device. We then develop open-source and accessible procedures to analyse the data, providing examples of insights that can be gleaned from the analysis of a large dataset. The database, graphics and analysis tools are made available to the community and will continue to evolve as an open-source initiative. This approach of extensively capturing the progress of an entire field, including sorting, interactive exploration and graphical representation of the data, will be applicable to many fields in materials science, engineering and biosciences.
Shaped Ceramics with Tunable Magnetic Properties from Metal-Containing Polymers (2000)

A shaped, magnetic ceramic was obtained from a metal-containing polymer network, which was synthesized by thermal polymerization of a metal-containing organosilicon monomer. Pyrolysis of a cylinder, shape, or film of the metal-containing polymer precursor produced a low-density magnetic ceramic replica in high yield. The magnetic properties of the shaped ceramic could be tuned between a superparamagnetic and ferromagnetic state by controlling the pyrolysis conditions, with the particular state dependent on the size of iron nanoclusters homogeneously dispersed throughout the carbosilane-graphitic-silicon nitride matrix. These results indicate that cross-linked metal-containing polymers may be useful precursors to ceramic monoliths with tailorable magnetic properties.
P418 Correlates of immune protection in the rabbit model of syphilis vaccination (2021)

<h3>Background</h3> An effective syphilis vaccine will be integral to efforts to eradicate this disease. Promising vaccine candidates are surface antigens of the syphilis spirochete, Treponema pallidum subsp. pallidum (T. pallidum). These antigens can be targeted by vaccination-induced opsonic antibodies and mediate pathogen immune clearance. Defining correlates of protection will aid in the identification of the best vaccine candidates. Here, we sought to investigate whether immunization with variants of the T. pallidum Repeat C (TprC) protein and the conserved NH2-terminus of the TprK induced protection and whether splenocyte proliferation and IFN-γ production correlated with protection. <h3>Methods</h3> Rabbits were immunized with either a cocktail of three recombinant, full-length TprC variants, or the NH2-terminus of the TprK protein with a RIBI-like adjuvant. Animals were challenged with T. pallidum intradermally (10 sites; 10^5 bacteria/site). Treponemal burden and progression to ulceration were monitored. To assess for immunogen-specific splenocytes, pools of synthetic peptides corresponding to each immunogen were used to stimulate splenocytes collected ex-vivo in proliferation assays. Supernatants from stimulated splenocytes were used to quantify IFN-γ responses by ELISA. <h3>Results</h3> Immunizations protected animals significantly albeit not completely. At day 35 post-challenge only 14.1% and 15.5% of lesions ulcerated in immunized rabbits compared to the 95% of lesions in unimmunized rabbits. At day 21, there was a 99.3% and 98.7% reduction in treponemal burden averaged across all challenge sites in TprC- and TprK-immunized rabbits compared to unimmunized animals, respectively. Lymphocyte proliferation and IFN-γ production correlated to reduction in both percent of ulcerated lesions and treponemal burden. <h3>Conclusions</h3> Lymphocyte proliferation and IFN-γ release assays may serve as surrogates to assess for antigen-specific T-cell responses. TprK and TprC immunizations are able to stimulate cellular immunity in a TH2 environment, which is key to development of an effective syphilis vaccine.
Natural Cystatin C fragments inhibit GPR15-mediated HIV and SIV infection without interfering with GPR15L signaling (2020)

SUMMARY GPR15 is a G protein-coupled receptor proposed to play a role in mucosal immunity that also serves as entry cofactor for HIV and SIV. To discover novel endogenous GPR15 ligands, we screened a hemofiltrate-derived peptide library for inhibitors of GPR15-mediated SIV infection. Our approach identified a C-terminal fragment of Cystatin C (CysC95-146) that specifically inhibits GPR15-dependent HIV-1, HIV-2 and SIV infection. In contrast, GPR15L, the chemokine ligand of GPR15, failed to inhibit virus infection. We found that Cystatin C fragments preventing GPR15-mediated viral entry do not interfere with GPR15L signaling and are generated by proteases activated at sites of inflammation. The antiretroviral activity of CysC95-146 was confirmed in primary CD4+ T cells and is conserved in simian hosts of SIV infection. Thus, we identified a potent endogenous inhibitor of GPR15-mediated HIV and SIV infection that does not interfere with the physiological function of this G protein-coupled receptor.
Analysis of Quinic Acid and of myo-Inositol in Tobacco (2012)

Abstract Quinic acid [D(-)-quinic acid, (1S, 3R,4S,5R)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid], and inositol [myoinositol, (1R,2R,3S,4S,5R,6S-cyclohexane-1,2,3,4,5,6-hexol or cis-1,2,3,5-trans-4,6-cyclohexane-hexol] are oxygenated compounds well known as tobacco constituents. Although mentioned in the literature as constituents of tobacco leaf as early as 1930, very little information is offered regarding the quantitation of quinic acid and inositol, up to the present day. This study describes a simple procedure for the analysis of quinic acid and myo-inositol in tobacco and reports the levels of these two analytes in various single grade and blended tobaccos from commercial and Kentucky reference cigarettes. The procedure is based on an original LC/MS/MS analysis of the tobacco extract. This method and its validation are described in this paper. A wide range of levels of the analytes was observed from sample to sample. Burley samples were in general low in both quinic acid and inositol compared to flue-cured tobaccos. The levels of myo-inositol detected in the analyzed samples were consistent with previously reported results for flue-cured tobaccos, but significantly lower than those reported for Burley. Besides myo-inositol, a number of naturally occurring stereoisomers of inositol are known. These include scyllo-, muco-, D-chiro- and neo-inositol. Other isomers are possible, including L-chiro-, allo-, epiand cis-inositol, but they are less common. No previous study has been reported regarding the evaluation of these compounds in tobacco, and the present study indicated that only myo-inositol and D(-)-quinic acid are found in tobacco.
Fine Pitch Micro-Bump Interconnections for Advanced 3D Chip Stacking (2011)

3D integration requires the realisation of electrical interconnects between multiple vertically stacked Si devices. Solder based, fine pitch, micro-bump connections are a promising approach for making die-to-die or die-to-wafer interconnections mainly due to its lower bonding temperature as compared with Cu-to-Cu thermo-compression bonding. This paper presents thin die stacking using Cu/Sn micro-bumps with dies containing Through Silicon Via (TSV). Two different approaches named Transient Liquid Phase (TLP) bonding and Solid State Diffusion (SSB) bonding are investigated.