gebhart/patrepeval huggingface dataset:
Nuclear Membranes and Plasma Membranes from Hen Erythrocytes (1971)

Abstract Nuclear membranes and plasma membranes isolated from mature hen erythrocytes differ widely in their phospholipid, cholesterol, and cholesterol ester composition. The plasma membranes contain relatively high amounts of sphingomyelin and cholesterol, as is known for plasma membranes from other cell types. The molar ratios of cholesterol to phospholipid are 1.04 for plasma membranes and 0.42 for nuclear membranes, whereas the molar ratios of cholesterol to sphingomyelin are nearly identical to both membranes (3.39 and 3.23, respectively). Appreciable amounts of alk-1-enyl-acyl and alkyl-acyl analogues of phosphoglycerides are present in both membranes. The individual phosphoglycerides show distinct patterns of ether analogues. The proportion of ether analogues is not different in nuclear membranes and plasma membranes. Similar characteristics are found in the fatty acid residues of the phosphoglycerides. Quantitative evaluation of the lipid data for whole cells, nuclear membranes, and plasma membranes is in correspondence with the 1:1 surface ratio of both membrane classes in this cell.
Analyse de la répartition des pertes de puissance dans un réducteur épicycloïdal, en utilisant la méthode des réseaux thermiques (2015)

Colloque avec actes et comité de lecture. Internationale.
A Fuzzy Inverse Model Construction Method for General Monotonic Multi-Input-- Single-Output (MISO) Systems (2008)

This paper presents a novel method of systematically constructing a fuzzy inverse model for general multi-input-single-output (MISO) systems represented with triangular input membership functions, singleton output membership function, and fuzzy-mean defuzzification. The fuzzy inverse model construction method has the ability of uniquely determining the inverse relationship for each input-output pair. It is derived in a straightforward way and the required input variables can be simultaneously obtained by the fuzzy inferencing calculation to realize the desired output value. Simulation examples are provided to demonstrate the effectiveness of the proposed method to find the inverse kinematics solutions for complex multiple degree-of-freedom industrial robot manipulators.
Evidence for spare α1-adrenoceptors for the accumulation of inositol phosphates in smooth muscle (1987)

The accumulation of inositol phosphates (IP) in smooth muscle from rat vas deferens and caudal artery was maximally increased 3- to 4-fold in response to exposure of the tissues to 100 microM noradrenaline. Clonidine (up to 3 mM) was a partial agonist. Pretreatment of the tissues with the irreversible alpha-adrenoceptor antagonist phenoxybenzamine (0.3-10 microM) shifted the noradrenaline concentration-response curve to the right before depressing the maximum. The maximum of the clonidine concentration-response curve was depressed without significant change in the EC50 by the same treatment. These data, which are most easily interpreted as demonstrating the presence of a receptor reserve for IP accumulation, are discussed.
Macrophage migration inhibitory factor (MIF) is necessary for progression of autoimmune diabetes mellitus (2007)

Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine of the innate immune system that plays a major role in the induction of immunoinflammatory responses. To examine the role of endogenous MIF in the pathogenesis of type 1 diabetes (TID) we evaluated the effects of administration of neutralizing anti-MIF antibodies to NOD mice with accelerated forms of diabetes induced by injection of cyclophosphamide or by transfer of diabetogenic spleen cells. Both accelerated forms of diabetes were markedly reduced by anti-MIF antibody. Furthermore, MIF-deficient (MIF(-/-)) mice were less susceptible to the induction of immunoinflammatory diabetes, insulitis and apoptosis within the endocrine pancreas by multiple low doses of streptozotocin (MLD-STZ) than genetically matched wild type (WT) mice. MIF deficiency resulted in lower proliferation and lymphocyte adhesion, as well as reduced production from the spleens and peritoneal cells of a variety of inflammatory mediators typically associated with development of the disease including IL-12, IL-23, TNF-alpha, and IL-1beta. Furthermore, MIF deletion affected the production of IL-18, TNF-alpha, IL-1beta, and iNOS in the islets of Langerhans. These data, along with the higher expression of IL-4 and TGF-beta observed in the periphery and in the pancreas of MLD-STZ-challenged MIF(-/-) mice as compared to WT controls suggest that MIF deficiency has induced an immune deviation towards protective type 2/3 response. These results suggest that MIF participates in T1D by controlling the functional activity of monocytes/macrophages and T cells and modulating their secretory capacity of pro- and anti-inflammatory molecules.
Differing Effects of Resibufagenin on Cinobufatalin- versus Marinobufagenin-Induced Preeclampsia in a Rodent Model (2014)

We conclude that more than one bufodienolide may induce the preeclamptic syndrome and that each may require a specific antagonist to prevent (or treat) the syndrome.
Development of Oxygen Semipermeable Membrane Using Mixed Conductive Perovskite-Type Oxides (Part 2) (1989)

In an attempt to develop an oxygen semipermeable membrane with an asymmetric structure using mixed conductive perovskite-type oxides, preparation of a dense La0.6Sr0.4CoO3 (LSCO) film on a porous LSCO substrate was studied by means of sputtering- and spray deposition-techniques. No dense overlayer formed by the sputtering technique, with large open pores of the substrate remaining uncovered. Moreover, the deposited overlayer showed many cracks after heating at temperatures between 1000° and 1400°C for crystallization of the overlayer. The spray deposition technique consisted of repetition of spraying an ethanol suspension of fine LSCO particles on the porous substrate at ca. 300°C and sintering for 1h in air at elevated temperature. It was found that efficiency in covering open pores of the substrate depends on the spray amount and the sintering temperature. Optimum conditions were 2-3mg·cm-2 of LSCO per one spray and 1400°C for sintering. Under these conditions, the open pores were covered progressively with repeating the procedure, and an almost completely dense overlayer about 15μm thick was obtained after repeating four times. The thin film element thus obtained showed a higher rate of oxygen semipermeation than that of a dense sintered disc, although the rate was lower than expected. Control of the chemical compositon at the film surface as well as the dispersion of open pores of the substrate was suggested to be important for improvement.
A Channel Estimation Technique for Dynamic Parameter Controlled - OF/TDMA Systems (2006)

This paper proposes a channel estimation technique for the dynamic parameter controlled - orthogonal frequency and time division multiple access (DPC-OF/TDMA) system. In the proposed scheme, channel impulse response that represents channel state information (CSI) is measured using a carrier interferometry (CI) which is equivalent to impulse transmission. Moreover, because the minimum unit (subchannel block) of subcarriers to be allocated to each terminal is 64 subcarriers, to achieve high accuracy of the estimated CSI with a spreading factor of 64, code-multiplexed pilot signal is applied to identify base station (BS) in the cell search process, and CSI between a terminal and each transmit antenna element in the BS is detected using a time-domain-multiplexed CI signal for ease of extension of the DPC-OF/TDMA to multi-input multi-output (IMO) systems. Furthermore, we will also propose a CSI estimation scheme flexible to the plural subchannel block assignment cases. Conmputer simulation confirms that the proposed scheme can estimate the CSI regardless of the number of subchannel blocks assigned to each terminal.
Evaluation of lipid-containing semipermeable membrane devices for monitoring organochlorine contaminants in the Upper Mississippi river (1995)

Abstract Organochlorine contaminants sequestered in lipid-containing semipermeable membrane devices (SPMDs) were compared to those found in tangential-flow ultrafilter permeates as part of a pilot study at 10 sites in the Upper Mississippi River system. Caged and feral fish from three primary sites were also analyzed for comparison. Concentrated organochlorine (OC) compounds were readily extracted from the SPMDs by dialysis into hexane, and samples were analyzed by gas chromatography-negative chemical ionization-mass spectrometry. Fish and water samples were processed by conventional methods. Reasonable agreement was found between analyte SPMD-derived water concentrations and measured values of ultrafilter permeates; however, concentrations of the same analytes in caged fish did not appear to be proportional to water concentrations derived from SPMDs and ultrafilter permeates. The greatest number of OC compounds was detected in SPMDs; fewer were detected in caged fish and feral fish.
Fabrication of frequency-selective surfaces using microlens projection photolithography (2002)

This letter describes the use of microlens projection photolithography (μLPL) for the fabrication of repetitive metallic micropatterns, and the application of these patterns as frequency-selective surfaces. Microlens projection photolithography uses an array of microlenses (diameter d=1–1000 micrometers) to project an array of images of an illuminated mask into photoresist. We converted these arrays into patterns in metals by electron beam evaporation and lift off. This technique can produce arrays over areas &amp;gt;10 cm2 with submicrometer feature sizes in a single exposure. We fabricated arrays of metallic micropatterns on substrates transparent to infrared radiation, and demonstrated that appropriate patterns acted as frequency-selective filters.
Taxonomy of Cupressaceae and Asteraceae and SDS-PAGE of purified allergenic proteins. (2015)

&lt;p&gt;&lt;b&gt;(A)&lt;/b&gt; Phylogenetic tree of Cupressaceae and Asteraceae species. &lt;b&gt;(B)&lt;/b&gt; Identity matrix of pectate lyase pollen allergens and, in case of Amb a 1, allergen isoforms. &lt;b&gt;(C)&lt;/b&gt; SDS-PAGE of allergenic pectate lyases purified from pollen extracts by anion-exchange chromatography and/or size exclusion chromatography. The gel was stained with Coomassie Brilliant Blue R-250. Natural Cry j 1 migrates as visible double band.&lt;/p&gt;
Does distributed development affect software quality? An empirical case study of Windows Vista (2009)

It is widely believed that distributed software development is riskier and more challenging than collocated development. Prior literature on distributed development in software engineering and other fields discuss various challenges, including cultural barriers, expertise transfer difficulties, and communication and coordination overhead. We evaluate this conventional belief by examining the overall development of Windows Vista and comparing the post-release failures of components that were developed in a distributed fashion with those that were developed by collocated teams. We found a negligible difference in failures. This difference becomes even less significant when controlling for the number of developers working on a binary. We also examine component characteristics such as code churn, complexity, dependency information, and test code coverage and find very little difference between distributed and collocated components to investigate if less complex components are more distributed. Further, we examine the software process and phenomena that occurred during the Vista development cycle and present ways in which the development process utilized may be insensitive to geography by mitigating the difficulties introduced in prior work in this area.
Modeling and Test of Nanostructure Fabricated on 160 nm Thin SOI Wafer for In-Ic Integration (2007)

In this article we present a complete study of a mechanical nanostructure of the kind of accelerometer. Our models include in particular impact of submicron phenomena such Casimir force considering conductivity of silicon, thickness and roughness of the NEMS. We use these new results to simulate the static and dynamic behavior of on the nano accelerometer like specific design. We fabricated a NEMS demonstrator and performed first electrical measurements that we compared to our model.
Perfluorochemical Erythrocyte Substitutes: Disposition and Effects on Drug Distribution and Elimination (1991)

As a result of their ability to transport oxygen, PFC emulsions are being investigated for possible use in a wide variety of conditions. The recent FDA approval of F-DA to diminish myocardial ischemia during angioplasty is the first marketing approval for such a product in the world. The many potential uses of such products may result in their common application in the future, especially as new and better products are developed. The elimination, distribution, and tissue retention of PFC emulsions as well as the physiological changes that occur upon their administration have been the subject of many investigations. The results indicate that these agents may influence the pharmacokinetic properties of other drugs by a wide variety of mechanisms. Several studies have shown significant, but not necessarily consistent, changes in drug elimination and distribution following PFC emulsion infusion. Changes appear dependent on the drug examined, emulsion utilized, degree of blood exchange, species utilized, and the controls chosen for comparison. Often, the changes are time dependent indicating the importance of conducting long-term studies. While PFC emulsions do not appear to alter renal elimination of drugs, several studies have demonstrated that these agents have the potential to induce drug metabolism from several days to possibly months after exposure. Observed changes in drug volumes of distribution, which are often time dependent, may be due to changes in normal drug transport throughout the circulation and/or changes in membrane permeability and cell transport mechanisms. Changes in drug transport may result from depletion of plasma proteins or increases in alpha 1-acid glycoprotein levels due to trauma or PFC emulsion effects. The binding of drugs by PFC emulsion droplets varies greatly and PFC emulsion components displace some plasma protein bound drugs. The wide variability in the results and conclusions of the pharmacokinetic studies conducted to date emphasize the importance of utilizing adequate controls to identify which alterations are PFC emulsion specific.
Estimation of electronic confinement in a quantum dot from envelope modulation of Coulomb blockade oscillations (1994)

Envelope modulation of Coulomb blockade oscillations has been observed in the conductance of a semiconductor quantum dot weakly connected to two reservoirs through tunneling barriers and subjected to magnetic fields. Although the number of conductance peaks per modulation period has been reported to be constant, we find that in moderate magnetic fields the number of peaks per period decreases one by one as gate voltage is changed. This results from the electronic depopulation of a single Landau level per modulation period. Comparing this result with calculated energy levels, the strength of electronic confinement is estimated to be 2.2 meV.
Concentrations of elements in fish fillets, fish muscle plugs, and crayfish from the 2011 Missouri Department of Conservation general contaminant monitoring program (2013)

This report presents the results of a contaminant monitoring survey conducted annually by the Missouri Department of Conservation to examine the levels of selected elemental contaminants in fish fillets, fish muscle plugs, and crayfish. Fillet samples of yellow bullhead (Ameiurus natalis), golden redhorse (Moxostoma erythrurum), longear sunfish (Lepomis megalotis), and channel catfish (Ictalurus punctatus) were collected from six sites as part of the Missouri Department of Conservation's Fish Contaminant Monitoring Program. Fish dorsal muscle plugs were collected from largemouth bass (Micropterus salmoides) at eight of the sites, and crayfish from two sites. Following preparation and analysis of the samples, highlights of the data were as follows: cadmium and lead residues were most elevated in crayfish tissue samples from the Big River at Cherokee Landing, with 1 to 8 micrograms per gram dry weight and 22 to 45 micrograms per gram dry weight, respectively. Some dorsal muscle plugs from largemouth bass collected from Clearwater Lake, Lake St. Louis, Noblett Lake, Hazel Creek Lake, and Harrison County Lake contained mercury residues (1.7 to 4.7 micrograms per gram dry weight) that exceeded the U.S. Environmental Protection Agency Water Quality Criterion of 1.5 micrograms per gram dry weight of fish tissue (equivalent to 0.30 micrograms per gram wet weight).
Sizing Optimization Methodology of a Surface Permanent Magnet Machine-Converter System Over a Torque-Speed Operating Profile: Application to a Wave Energy Converter (2011)

This paper sets forth a sizing optimization methodology of a surface permanent magnet machine-converter system over a torque-speed operating profile. The two optimization objectives are to minimize the cost of the machine-converter system and to minimize (or maximize) electrical energy consumption (or generation). The optimization parameters serve to describe both the machine geometry and the electrical ratings of the electronic power converter. Each operating point of the profile is treated independently, and current control is optimized at every operating point to not only minimize machine drive losses but also satisfy several constraints and then implicitly considering flux-weakening possibility. This optimization methodology is generic and is applied to a particular case: a direct-drive conversion chain for a wave energy converter (WEC). We show that taking into account both the sizing parameters of the converter and the flux-weakening control, in addition to the classical sizing parameters of the machine, has a strong impact on the machine-converter system optimal results. Moreover, the strong coupling with the WEC through damping parameters plays also a crucial role on the sizing results.
Photography-based real-time long-wave infrared scattering estimation technique (2021)

The scattered light distribution of surfaces in the long-wave infrared (<i>λ</i>∼8-12µ<i>m</i>) is measured using a small set of thermal camera images. This method can extract scatter patterns considerably faster than standard laboratory bidirectional reflectance distribution function measurements and is appropriate for passive homogeneous surfaces. Specifically, six images are used in this study, each taken with respect to a thermal light source at an angle ranging from 10° to 60° to the normal of the surface. This data is deconvolved with the shape of the light source to estimate the scattering pattern. Both highly specular (black Masonite) and diffuse (painted drywall) surfaces are tested. Errors between the estimated scattering distribution and a directly measured one using a goniometer stage and quantum-cascade laser (QCL) are less than or equal to 3% except for extremely specular surfaces where viable QCL measurements cannot be made due to the increased relative contribution of speckle noise.
Isostructurality in three-component crystals achieved by the combination of persistent hydrogen bonding motifs and solvent inclusion (2012)

We demonstrate how solution crystallization of lamotrigine with flexible alkane dicarboxylic acids with different chain lengths (adipic acid and pimelic acid) generates a series of four isostructural solvated three-component salts. The analysis of their crystal structures shows that isostructurality is achieved by the combination of robust hydrogen bonding motifs and the incorporation of solvent guest molecules.
Disposable endoscope tip actuation design and robotic platform (2010)

A disposable endoscopic platform with actuation motors inside the body of the endoscope is presented. This platform can enable new medical devices for diagnosis and for minimally invasive surgeries. This paper addresses mechanical and safety issues with existing endoscope technologies by incorporating disposability, safety modules, and lower cable forces. In order to produce path-independent cable forces, motors are incorporated in the body of the endoscope near the bending tip. Results for tip forces are shown accompanied by an analytical model describing the scaling laws for this type of robotic architecture. The system under development will provide a platform for research into haptic control and perceptual feedback.
Cross Metathesis on Olefin-Terminated Monolayers on Si(111) Using the Grubbs' Catalyst (2006)

This paper reports the functionalization and patterning of olefin-terminated monolayers on Si(111) through cross metathesis. A simple, one-step synthesis of a diolefin--CH2=CH(CH2)9O(CH2)9CH=CH2--was developed from commercially available starting materials. Mixed partially olefin-terminated monolayers of this novel diolefin and 1-octadecene on hydrogen-terminated Si(111) were obtained. The olefins are raised above the rest of the monolayer and thus sterically accessible for further functionalization. Olefin-terminated monolayers were reacted with the Grubbs' first generation catalyst and olefins in solution that were terminated with fluorines, carboxylic acids, alcohols, aldehydes, and alkyl bromides. Characterization of these monolayers using X-ray photoelectron spectroscopy and horizontal attenuated total reflection infrared spectroscopy demonstrated that olefins on the surface had reacted via cross metathesis to expose fluorines, carboxylic acids, aldehydes, alcohols, and bromides. Through calibration experiments, we demonstrated a simple 1:1 correspondence between the ratio of olefins in solution used in the assembly and the final composition of the mixed monolayers. Finally, these monolayers on silicon were patterned on the micrometer-size scale by soft lithography using microfluidic channels patterned into poly(dimethylsiloxane) (PDMS) stamps. Micrometer-wide lines of polymer brushes were synthesized on these monolayers and characterized by scanning electron microscopy. In addition, olefin-terminated monolayers were patterned into micrometer-sized lines exposing carboxylic acids by cross metathesis with olefins in solution. This method of patterning is broadly applicable and can find applications in a variety of fields including the development of biosensors and nanoelectronics.
ChemInform Abstract: Cristobalite Phase Formation in Glass/Ceramic Composites. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Integration of Statistical Techniques in the Design Curriculum (2007)

Traditionally, design and analysis techniques have been using abstractions and models that are well captured using probabilistic models and are treated using standard algorithmic techniques. However, technology progress and application diversification, created a need for considering the impact of non-Gaussian and non-uniform uncertainty distributions that can only be addressed using non-parametric statistical techniques and robust algorithms. This trend provided an impetus for creation of a new graduate level course that aims to teach students sound statistical techniques, to enable them to obtain hands-on experience using statistical software, and to develop and apply the most effective ways to address design and manufacturing uncertainties. We summarize the syllabus of the course that integrates statistical techniques in the design curriculum, identifying the major obstacles and suggesting future improvements.