gebhart/patrepeval huggingface dataset:
Optical properties of a novel fluorene‐based thermally stable conjugated polymer containing pyridine and unsymmetric carbazole groups (2009)

Abstract A new diiodo monomer containing heterocyclic pyridine and carbazole groups was synthesized via Chichibabin reaction and used in the preparation of a conjugated polymer via Suzuki coupling approach. The conjugated polymer was highly soluble in common organic solvents such as NMP, THF, dichloromethane, chloroform, toluene, xylene, and benzene at room temperature. The polymer had high glass transition temperature at 191 °C and T d10 at 434 °C in nitrogen atmosphere. The pristine polymer exhibited the UV–vis maximum absorption at 355 nm and shifted to 420 nm after protonation. The emission of the polymer in THF solution changed from the blue region with maximum peak at 400 nm to the yellow region with maximum peak at 540 nm after protonated by HCl, and the intensity of emission depended on the concentration of acid. The polymer also showed electrochromic behavior under applied voltage. The emission color of the polymer film changed from blue (435 nm) to yellow (570 nm) when 2.5 V bias voltage was applied. The polymer also exhibited write‐once and read‐many‐times (WORM) polymer memory effect with tristable states. © 2009 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 47: 991–1002, 2009
Establishing a Molecular Mechanism for the Beckmann Rearrangement of Oximes over Microporous Molecular Sieves (2005)

At least two possible pathways were found for the Beckmann rearrangement of acetophenone oxime to acetanilide over zeolite catalysts. In the first step, the N atom of the oxime is protonated over the Brønsted acid sites of an aluminum siliceous zeolite (see picture), but not over the silanol groups of a pure siliceous zeolite.
Onset of three-dimensional shear in granular flow. (2005)

The evolution of granular shear flow is investigated as a function of height in a split-bottom Couette cell. Using particle tracking, magnetic-resonance imaging, and large-scale simulations, we find a transition in the nature of the shear as a characteristic height H* is exceeded. Below H* there is a central stationary core; above H* we observe the onset of additional axial shear associated with torsional failure. Radial and axial shear profiles are qualitatively different: the radial extent is wide and increases with height, while the axial width remains narrow and fixed.
Hydrophobic photolabelling of pertussis toxin subunits interacting with lipids (1986)

The hydrophobic surfaces presumably involved in the membrane interaction of pertussis toxin have been mapped by a new detergent-binding assay. This is based on the interdispersion among detergent micelles of trace amounts of radioactive photoreactive phospholipid analogues, able to cross-link to the protein thereby labelling its detergent-binding domains. The assay has proven to be very sensitive. Subunits B1, B2 and B3 of pertussis toxin were found to interact with the lipid micelles suggesting that they may be involved in the membrane penetration step of the intoxication process.
Computed tomography‐based tissue‐engineered scaffolds in craniomaxillofacial surgery (2007)

Computationally designed scaffolds can support masticatory function in a large animal model as well as both osseous and cartilage regeneration. Our group is continuing to evaluate multiple implant designs in both young and mature Yucatan minipig animals.
中学校における新しい国際交流プログラムの開発III : Exploris Middle School・Odyssey School・MENDOYO SMP4との交流を通して (2011)

本研究では, インドネシアのMENDOYO SMP4の来日交流, アメリカのExploris Middle Schoolの渡米交流及びOdyssey Schoolとの宮島交流による実践を通して, 中学校における新しい国際交流プログラムの指針を示そうとした。2008年度の研究結果から, 語学力が充分でない中学生が国際交流を進めるためには, 伝えたい内容を明確にする指導・支援が必要であることが分かった。今年度はこれまでの成果を踏まえ, 伝えたい内容を明確に持たせ参加型の交流を設定し, 最終的な目標達成に向けて意思疎通ができることに重点を置いた。言語の違いはあるが, 活動内容に伴って相互理解の質が変容することが明確になった。
Influence of Tip Clearance on the Flow Field and Aerodynamic Performance of the Centrifugal Impeller (2002)

This paper studies numerically the influence of the tip clearance on the three-dimensional viscous flowfield and performance of the NASA Low-Speed Centrifugal Compressor (LSCC) impeller with a vaneless diffuser. A three-dimensional viscous code developed by the authors is applied with several acceleration methods: local time-step, multigrid and residual smoothing. The computations were performed under several operating conditions with four different tip clearance sizes (0.0%, 50%, 100% and 200% design tip-clearance). The numerical results show that: (1) the throughflow wake is considerably influenced by the tip-clearance. The low-kinetic-energy fluid accumulated in the shroud/pressure side of the unshrouded impeller, but in the shroud/suction region for 0.0 tip clearance; (2) there possibly exists an optimum size of the tip-clearance which is not the zero tip clearance to make the flow loss minimized.
Coarse and fine bit synchronization for WDM interconnections using two subcarrier-multiplexed control pilot tones (1999)

We demonstrate the use of high- and low-frequency subcarrier-multiplexed pilot tones as control signals to achieve both coarse and fine synchronization in a bit-parallel wavelength-division-multiplexed optical interconnection. These control signals are located on each of the two outer wavelengths and are combined with the baseband data before transmission. The phase difference of the tones enables: (1) fine synchronization to <1/8 of a bit time in the optical domain for all wavelength channels simultaneously by comparing the high-frequency tones and using a discrete set of wavelength-dependent delays and (2) coarse synchronization over several bit times in the electrical domain by comparing the low-frequency tones and using shift registers.
Tantalum-neopentylidene hydride and tantalum-neopentylidyne hydride complexes (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTTantalum-neopentylidene hydride and tantalum-neopentylidyne hydride complexesJ. D. Fellmann, H. W. Turner, and R. R. SchrockCite this: J. Am. Chem. Soc. 1980, 102, 21, 6608–6609Publication Date (Print):October 8, 1980Publication History Published online1 May 2002Published inissue 8 October 1980https://pubs.acs.org/doi/10.1021/ja00541a061https://doi.org/10.1021/ja00541a061research-articleACS PublicationsRequest reuse permissionsArticle Views370Altmetric-Citations38LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Identifying and Predicting Temporal Change of Basic Human Values from Social Network Usage (2017)

Basic Human Values represent a set of values such as security, independence, success, kindness, and pleasure what we think are important to our lives. Each of us holds different values with different degrees of importance. Existing studies show that values of a person can be identified from her social network usage. However, the value priority of a person may change over time due to different factors such as time, event, influence, social structure, and technology. In this research, we are the first to investigate whether the change of value priorities can be identified from social network usage. We have proposed a HMM based technique to capture the change of values of a person.
The virtual peripheral nerve academy: education for the identification and treatment of peripheral nerve disorders (2022)

Millions of people around the globe suffer peripheral nerve injuries caused by trauma and medical disorders. However, medical school curricula are profoundly deficient in peripheral nerve education. This lack of knowledge within the healthcare profession may cause inadequate patient care. We developed the Virtual Peripheral Nerve Academy (VPNA) as a reusable virtual learning environment to provide medical students with detailed education on the peripheral nervous system (PNS). Students are introduced to the PNS through virtual 3D rendering of the human body, wherein they visualize individual nerves through dissection and observe normal motor and sensory function associated with each nerve. PNS structures that are absent from traditional texts are included in this visualization, ranging from the innervation of joints to the normal anatomic variation required for differential diagnosis of pain after an injury. Detailed modules on peripheral nerve disorders allow students to observe pathophysiological mechanisms, associated symptomatology, and appropriate treatments. Students are briefed on a patient clinical case, then interact with a patient avatar to learn the appropriate diagnostics, including physical exam maneuvers and electrodiagnostic testing. Interactive modules on peripheral nerve surgeries detail surgical techniques. The VPNA data and analytics dashboards allow medical students and course instructors to assess skill improvement and identify specific learning needs. The built-in learner management system and availability on both computer-based and virtual reality platforms facilitate integration into any existing medical school curricula. Ultimately, this immersive technology enables every medical student to learn about the peripheral nervous system and gain competency in treating real-life nerve pathologies.
Sequential Pattern mining of Longitudinal Adverse Events After Left\n Ventricular Assist Device Implant (2019)

Left ventricular assist devices (LVADs) are an increasingly common therapy\nfor patients with advanced heart failure. However, implantation of the LVAD\nincreases the risk of stroke, infection, bleeding, and other serious adverse\nevents (AEs). Most post-LVAD AEs studies have focused on individual AEs in\nisolation, neglecting the possible interrelation, or causality between AEs.\nThis study is the first to conduct an exploratory analysis to discover common\nsequential chains of AEs following LVAD implantation that are correlated with\nimportant clinical outcomes. This analysis was derived from 58,575 recorded AEs\nfor 13,192 patients in International Registry for Mechanical Circulatory\nSupport (INTERMACS) who received a continuousflow LVAD between 2006 and 2015.\nThe pattern mining procedure involved three main steps: (1) creating a bank of\nAE sequences by converting the AEs for each patient into a single,\nchronologically sequenced record, (2) grouping patients with similar AE\nsequences using hierarchical clustering, and (3) extracting temporal chains of\nAEs for each group of patients using Markov modeling. The mined results\nindicate the existence of seven groups of sequential chains of AEs,\ncharacterized by common types of AEs that occurred in a unique order. The\ngroups were identified as: GRP1: Recurrent bleeding, GRP2: Trajectory of device\nmalfunction &amp; explant, GRP3: Infection, GRP4: Trajectories to transplant, GRP5:\nCardiac arrhythmia, GRP6: Trajectory of neurological dysfunction &amp; death, and\nGRP7: Trajectory of respiratory failure, renal dysfunction &amp; death. These\npatterns of sequential post-LVAD AEs disclose potential interdependence between\nAEs and may aid prediction, and prevention, of subsequent AEs in future\nstudies.\n
Scalability and stacking of self-stratifying microbial fuel cells treating urine (2020)

The scalability of Microbial fuel cells (MFCs) is key to the development of stacks. A recent study has shown that self-stratifying membraneless MFCs (S-MFCs) could be scaled down to 2 cm without performance deterioration. However, the scaling-up limit of S-MFC is yet unknown. Here the study evaluates the scale-up height of S-MFCs treating urine, from 2 cm, 4 cm to 12 cm high electrodes. The electrochemical properties of the S-MFCs were investigated after steady-states were established, following a 70-days longevity study. The electrochemical properties of the 2 cm and 4 cm conditions were similar (5.45 ± 0.32 mW per cascade). Conversely, the 12 cm conditions had much lower power output (1.48 ± 0.15 mW). The biofilm on the 12 cm cathodes only developed on the upper 5-6 cm of the immersed part of the electrode suggesting that the cathodic reactions were the limiting factor. This hypothesis was confirmed by the cathode polarisations showing that the 12 cm S-MFC had low current density (1.64 ± 9.53 µA cm<sup>-2</sup>, at 0 mV) compared to the other two conditions taht had similar current densities (192.73 ± 20.35 µA cm<sup>-2</sup>, at 0 mV). These results indicate that S-MFC treating urine can only be scaled-up to an electrode height of around 5-6 cm before the performance is negatively affected.
ISSCR Guidelines for Stem Cell Research and Clinical Translation: The 2021 update (2021)

The International Society for Stem Cell Research has updated its Guidelines for Stem Cell Research and Clinical Translation in order to address advances in stem cell science and other relevant fields, together with the associated ethical, social, and policy issues that have arisen since the last update in 2016. While growing to encompass the evolving science, clinical applications of stem cells, and the increasingly complex implications of stem cell research for society, the basic principles underlying the Guidelines remain unchanged, and they will continue to serve as the standard for the field and as a resource for scientists, regulators, funders, physicians, and members of the public, including patients. A summary of the key updates and issues is presented here.
Migration towards High Speed Optical Access Enabled by WDM Techniques (2009)

Different options for the seamless evolution of a WDM PON toward 10 Gb/s channel rate are compared and experimentally investigated. Although today 10 Gb/s is not yet cost effective for a fibre access network, it can become a viable option in the next years, pushed by the demand of new, bandwidth hungry services and enabled by recent technology advancements.
Broadly neutralizing antibodies targeting a conserved silent face of spike RBD resist extreme SARS-CoV-2 antigenic drift (2023)

Developing broad coronavirus vaccines requires identifying and understanding the molecular basis of broadly neutralizing antibody (bnAb) spike sites. In our previous work, we identified sarbecovirus spike RBD group 1 and 2 bnAbs. We have now shown that many of these bnAbs can still neutralize highly mutated SARS-CoV-2 variants, including the XBB.1.5. Structural studies revealed that group 1 bnAbs use recurrent germline-encoded CDRH3 features to interact with a conserved RBD region that overlaps with class 4 bnAb site. Group 2 bnAbs recognize a less well-characterized "site V" on the RBD and destabilize spike trimer. The site V has remained largely unchanged in SARS-CoV-2 variants and is highly conserved across diverse sarbecoviruses, making it a promising target for broad coronavirus vaccine development. Our findings suggest that targeted vaccine strategies may be needed to induce effective B cell responses to escape resistant subdominant spike RBD bnAb sites.
Nonlinearity in a Medical Ultrasound Probe Under High Excitation Voltage (2020)

Tissue harmonic imaging is often the preferred ultrasound imaging modality due to its ability to suppress reverberations. The method requires good control of the transmit stage of the ultrasound scanner, as harmonics in the transmitted ultrasound pulses will interfere with the harmonics generated in the tissue during nonlinear propagation, degrading image quality. In this study, a medical ultrasound probe used in tissue harmonic imaging was experimentally characterized for transmitted second-harmonic distortion to identify and compare the sources of nonlinear distortion in the probe and transmit electronics. The system was tested up to amplitudes above what is found during conventional operation, pushing the system to the limits in order to investigate the phenomenon. Under these conditions, second-harmonic levels up to -20 dB relative to the fundamental frequency were found in the ultrasound pulses transmitted from the probe. The transmit stage consists of high-voltage transmit electronics, cable, tuning inductors, and the acoustic stack. The contribution from the different stages in the ultrasound transmit chain was quantified by separating and measuring at different positions. Nonlinearities in the acoustic transducer stack were identified as the dominating source for second harmonics in the transmitted ultrasound pulses. Contribution from other components, e.g., transmit electronics and cable and tuning circuitry, were found to be negligible compared with that from the acoustic stack. Investigation of the stack's electrical impedance at different driving voltages revealed that the impedance changes significantly as a function of excitation voltage. The second-harmonic peak in the transmitted pulses can be explained by this nonlinear electrical impedance distorting the driving voltage and current.
Expanded haemodialysis: from operational mechanism to clinical results (2018)

Recent advances in chemical composition and new production techniques resulted in improved biocompatibility and permeability of dialysis membranes. Among these, the creation of a new class of membranes called medium cut-off (MCO) represents an important step towards improvement of clinical outcomes. Such membranes have been developed to improve the clearance of medium to high molecular weight (MW) solutes (i.e. uraemic toxins in the range of 5-50 kDa). MCO membranes have peculiar retention onset and cut-off characteristics. Due to a modified sieving profile, MCO membranes have also been described as high-retention onset. The significant internal filtration achieved in MCO haemodialysers provides a remarkable convective clearance of medium to high MW solutes. The marginal loss of albumin observed in MCO membranes compared with high cut-off membranes is considered acceptable, if not beneficial, producing a certain clearance of protein-bound solutes. The application of MCO membranes in a classic dialysis modality characterizes a new technique called expanded haemodialysis. This therapy does not need specific software or dedicated hardware, making its application possible in every setting where the quality of dialysis fluid meets current standards.
Spectrum Estimation of Density Operators with Alkaline-Earth Atoms (2018)

We show that Ramsey spectroscopy of fermionic alkaline-earth atoms in a square-well trap provides an efficient and accurate estimate for the eigenspectrum of a density matrix whose n copies are stored in the nuclear spins of n such atoms. This spectrum estimation is enabled by the high symmetry of the interaction Hamiltonian, dictated, in turn, by the decoupling of the nuclear spin from the electrons and by the shape of the square-well trap. Practical performance of this procedure and its potential applications to quantum computing and time keeping with alkaline-earth atoms are discussed.
Inflammatory Properties of Iron-Containing Carbon Nanoparticles (2007)

Inflammatory responses following exposure of carbon nanoparticles to human macrophage and endothelial cells were employed as indicators of particulate biological activity. Hundred nanometer carbon particles (nC) with and without nonextractable surface-bound iron were synthesized using a templating approach, and human monocyte-derived macrophages (MDM) were exposed to various concentrations of these particulates. Supernatants recovered from MDM 24 h postexposure were assayed for the inflammatory cytokine tumor necrosis factor-alpha (TNFalpha) by a quantitative ELISA and tested for their ability to induce expression of intercellular adhesion molecule-1 (ICAM-1) on human endothelial cells (EC) by immunofluorescence flow cytometry. Data generated by these experiments demonstrated that nC-Fe was far more biologically active than nC. In addition, the chemical reactivity of nC-Fe toward decomposition of hydrogen peroxide to form hydroxyl radicals was significantly higher than that of nC and correlated well with the increase in the strength of the inflammatory response, though a direct proof of creation of hydroxyl radicals in the biological system is not provided. Comparison with micrometer-sized carbon and carbon-iron particles suggests that the chemical and biological reactivity is correlated with surface area.
The limiting mobility of DNA sequencing fragments for both cross‐linked and noncross‐linked polymers in capillary electrophoresis: DNA sequencing at 1200 V cm−1 (1996)

The mobility of DNA sequencing fragments was measured in Long-Ranger gels at an electric field ranging from 200 to 1200 V cm-1 and in noncross-linked polyacrylamide at electric fields ranging from 100 to 300 V cm-1. In both cases, N*, the fragment length that denotes the onset of biased reptation with orientation, is inversely proportional to electric field. The inverse dependence of N* is inconsistent with the original biased reptation model but is consistent with modern models of DNA migration. While separation speed increases dramatically with electric field, the number of bases determined in a separation decreases in proportion to field strength. We present a DNA sequencing run at an electric field of 1200 V cm-1. Roughly 200 bases of sequence are determined in 3.5 min.
TEAVIGO<sup>TM</sup> (Epigallocatechin Gallate) Supplementation Prevents Obesity in Rodents by Reducing Adipose Tissue Mass (2005)

This study shows for the first time that supplementation with the most abundant green tea polyphenol, EGCG, abolishes diet-induced obesity. This effect is at least partly mediated via a direct influence on adipose tissue. Thus, dietary supplementation with EGCG should be considered as a valuable natural treatment option for obesity.
LUNG TRANSPLANTATION IN RECIPIENTS 70 YEARS OF AGE AND OLDER (2008)

Toyoda, Y; Bermudez, C; Zenati, M; Hattler, B; Crespo, M; Pilewski, J; McCurry, K Author Information
Cryptococcus Neoformans Glucuronoxylomannan Fractions of Different Molecular Masses are Functionally Distinct (2014)

GXM fractions of variable molecular masses bound to the surface of a C. neoformans acapsular mutant in a punctate pattern that is in contrast to the usual annular pattern of surface coating observed when GXM samples containing the full molecular mass range were used. The polysaccharide samples were also significantly different in their ability to stimulate cytokine production by host cells. Our findings indicate that GXM fractions are functionally distinct depending on their mass.
Supplementary Tables from Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer (2023)

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