gebhart/patrepeval huggingface dataset:
Instructional Course Lectures, The American Academy of Orthopaedic Surgeons - Periprosthetic Fracture of the Femur after Total Hip Arthroplasty. Treatment and Results to Date*† (1997)

LEWALLEN, DAVID G. M.D.‡; BERRY, DANIEL J. M.D.‡, ROCHESTER, MINNESOTA Author Information
Calculated optical properties of 64 trinucleoside diphosphates (1967)

Abstract The optical rotatory dispersion and ultraviolet absorption spectra of the 64 trinucleoside diphosphates containing the bases A, U, C, and G have been calculated by using a simple semiempirical approach. These calculations accurately predict the optical properties of the nine trimers for which extensive experimental results are available. The computed optical data should be useful in the identification of oligonucleotides obtained in the course of sequence determination of ribonucleic acids and should simplify the determination of the concentration of oligonucleotides in aqueous solution. Additional calculations indicate that it should be possible to analyze most, mixtures of sequence isomers of trinucleoside diphosphates by direct, measurement of the ORD of the mixture at neutral pH.
Régulation d'impédance d'un convertisseur de puissance de type Katium (2008)

International audience
A 4.8x Faster FPGA-Based Iterative Closest Point Accelerator for Object Pose Estimation of Picking Robot Applications (2019)

An FPGA-based accelerator for the iterative-closest-point (ICP) algorithm has been proposed, which achieves 4.8-times-faster object-pose estimation by a picking robot compared with the state-of-the-art technique. Experiments of the proposed FPGA-based ICP accelerator using Amazon Picking Contest data sets have confirmed that the object-pose estimation by the ICP takes only 0.6 seconds, and the entire picking process takes 2.0 seconds with power consumption of 6.0 W.
Destruction and Reorganization of Physically Cross-Linked Network of Thermoplastic Polyurethane Depending on Its Glass Transition Temperature (2019)

The mechanical behavior and morphological variation of thermoplastic polyurethanes (TPUs) with different hard segment contents (HSCs) deformed at different temperatures are investigated using tensile machine, small-angle X-ray scattering (SAXS), and wide-angle X-ray scattering (WAXS) techniques. The average constraint molecular weight ⟨Mc⟩ between the hard domains, calculated from the stress–strain curve, increases with the increasing deformation temperature and decreases with the increasing HSC. The increased ⟨Mc⟩ is also confirmed by the increased long spacing calculated from the SAXS peak. The intensity increase of the SAXS peak at high deformation temperature indicates that the induced hard domains exhibit higher density. The WAXS patterns indicate the induction of crystal form III at the deformation temperature above the Tg of the hard domains. The starting true stress of the generation of form III lies in the interval between 20 and 35 MPa. The orientation degree of chain segments at high temperature is lower as compared to deformation at low temperature. The fracture mechanism of TPUs deformed above and below the Tg of the hard domain is different. The conclusion is a quite useful guidance for TPU processing.
Nonlinear bubble dynamics (1988)

The standard approach to the analysis of the pulsations of a driven gas bubble is to assume that the pressure within the bubble follows a polytropic relation of the form p=p0(R0/R)3κ, where p is the pressure within the bubble, R is the radius, κ is the polytropic exponent, and the subscript zero indicates equilibrium values. For nonlinear oscillations of the gas bubble, however, this approximation has several limitations and needs to be reconsidered. A new formulation of the dynamics of bubble oscillations is presented in which the internal pressure is obtained numerically and the polytropic approximation is no longer required. Several comparisons are given of the two formulations, which describe in some detail the limitations of the polytropic approximation.
Learning-based noise reduction method for incoherent digital holography (2022)

The reconstructed image acquired from the incoherent holographic system contains a high degree of the grainy noise component. We propose a learning-based noise reduction scheme to mitigate such noise in the complex-valued domain.
Broadband Single-Stage Models for Microwave Band-Pass Filters (2006)

A single-stage expandable equivalent circuit is proposed to model a microwave band-pass filter up to several times its passband frequency. The equivalent circuit adopts a modified T-equivalent network to achieve an extremely large bandwidth. The modeled results for a 2.4 GHz WLAN bandpass filter fabricated in LTCC technology demonstrate good agreement with the measured results over a frequency range up to 8.5 GHz. Such a broadband model can be used to accurately predict the suppression of harmonics and interferences in system simulation of wireless front-end modules
Hints of Growth Mechanism Left in Supercrystals (2023)

Supercrystals of DNA-functionalized nanoparticles are visualized in three dimensions using X-ray ptychographic tomography, and their reciprocal spaces are mapped with small-angle X-ray scattering in order to better understand their internal defect structures. X-ray ptychographic tomography reveals various types of defects in an assembly that otherwise exhibits a single crystalline diffraction pattern. On average, supercrystals composed of smaller nanoparticles are smaller in size than supercrystals composed of larger particles. Additionally, supercrystals composed of small nanoparticles are typically aggregated into larger "necklace-like" structures. Within these larger structures, some but not all pairs of connected domains are coherent in their relative orientations. In contrast, supercrystals composed of larger nanoparticles with longer DNA ligands typically form faceted crystals. The combination of these two complementary X-ray techniques reveals that the crystalline assemblies grow by aggregation of smaller assemblies followed by rearrangement of nanoparticles.
Supplementary Table S3 from A Phase I/II Trial of HER2 Vaccine–Primed Autologous T-Cell Infusions in Patients with Treatment Refractory HER2–Overexpressing Breast Cancer (2023)

&lt;p&gt;Immunologic parameters pre-treatment between PR+SD and PD patients.&lt;/p&gt;
Silanizing Glassware (1997)

Glassware is silanized (siliconized) to prevent adsorption of solute to glass surfaces or to increase its hydrophobicity. This is particularly important with low concentrations of particularly "sticky" solutes such as single-stranded nucleic acids or proteins. This appendix provides a protocol for treating glassware.
Random and channeled energy loss in thin germanium and silicon crystals for positive and negative 2-15-GeV/cpions, kaons, and protons (1978)

Energy loss of 2-, 6-, and 15-GeV/c positive and negative protons, kaons, and pions transmitted through thin germanium and silicon crystals are measured using the crysta\l{}s as intrinsic detectors. For particles incident in directions far from axial or planar directions the results are in accord with the relativistic Beth\'e-Bloch stopping theory. The density effect plays an important role at these energies. The spectral distribution of energy losses is in good agreement with the Landau distribution. For positive particles aligned with an axis or a plane, the energy loss is considerably reduced compared to random. The measurements agree well with theoretical calculations. Negative particles, well aligned to a crystal axis, show increased energy loss compared to random by as much as \ensuremath{\sim}20%.
Heterogeneity in the clinical phenotype of TP53 mutations in breast cancer patients (2000)

TP53 mutation is a strong independent marker for survival in breast cancer with some heterogeneity in the clinical phenotype of various types of mutations. Based on 315 patients with breast carcinoma, we suggest a new model for the differentiation of TP53 mutations. Although TP53 mutation in general was associated with aggressive tumor/patient characteristics, missense mutations outside any conserved or structural domain did not affect the clinical outcome (risk of disseminated disease and death). In contrast, patients with missense mutations affecting amino acids directly involved in DNA or zinc binding displayed a very aggressive clinical phenotype. Null mutations (including missense mutations disrupting the tetramerization domain) and the remaining missense mutations displayed an intermediate aggressive clinical phenotype. When patients with primary early breast cancer were divided into three groups (wild-type together with missense mutations outside structural/conserved domains, null mutations and missense mutations with intermediate clinical phenotype, and very aggressive missense mutations), disease-specific survival rates were 89%, 58%, and 35% (5-year actuarial values, P < 0.0001), respectively. In a Cox proportional hazards analysis, separation of TP53 mutations according to these criteria eliminated the prognostic importance of all investigated classical factors except nodal status.
General Synthetic Strategies (1998)

The prelims comprise: Introduction General Guidelines Brief Survey of the History of Liquid Crystal Synthesis Common Reactions in Liquid Crystal Synthesis Building Blocks and Their Precursors Chirality: the Preparation and Use of Enantiomers Liquid Crystal Synthesis in Education and a Note on the Purification of Liquid Crystals References
Supplemental Figure 1 from Expression of CD14, IL10, and Tolerogenic Signature in Dendritic Cells Inversely Correlate with Clinical and Immunologic Response to TARP Vaccination in Prostate Cancer Patients (2023)

&lt;p&gt;Patient Baseline Parameters and their correlation with Clinical Response measurements&lt;/p&gt;
Colonic smooth muscle cells possess a different subtype of somatostatin receptor from gastric smooth muscle cells (1997)

Somatostatin (SS) alters colonic motility. To investigate whether SS has a direct effect on colonic smooth muscle cells, we prepared isolated muscle cells from the descending guinea pig colon and compared the effects of SS with those on isolated gastric smooth muscle cells. In gastric cells, SS had no effect on carbachol-induced contraction, whereas in colonic cells it caused inhibition. In colonic muscle cells, SS-28 caused >85% inhibition of contraction by cholecystokinin octapeptide (CCK-8), bombesin, 12-O-tetradecanoylphorbol-13-acetate, and ionomycin, whereas it had no effect on contraction by these agents in gastric cells. In gastric cells, SS inhibited relaxation. Three synthetic SS analogs had different relative affinities for causing effects in gastric and colonic cells. Pertussis toxin inhibited the action of SS-28 in each muscle cell type by 50-75%. SS-28 alone had a small contractile effect on cells from the circular layer of the colon. SS-28 inhibited carbachol-induced contraction in colonic cells from both the longitudinal and circular layers. These results demonstrate that the action of SS differs in colonic and gastric smooth muscle cells. SS inhibits contractants in colonic cells and relaxants in gastric cells. In colonic cells, SS has a weak contractile effect due to an effect on circular muscle cells and an inhibitory effect on cells from both longitudinal and circular layers. A different SS receptor subtype mediates the actions of SS in colonic and gastric muscle cells. In both cell types, the actions of SS are mediated by pertussis toxin-sensitive and -insensitive G proteins.
Synthetic DNA‐Targeted Chemotherapeutic Agents and Related Tumor‐Activated Prodrugs (2003)

Abstract Synthetic drugs have always played an important role in cancer therapy. The first systemic anticancer drugs were synthetic DNA alkylating agents and DNA antimetabolites. Nitrogen mustards, platinum complexes, nitrosoureas, and triazene‐based DNA‐methylating agents remain important DNA alkylators. Methotrexate, and more recent lipophilic analogs, together with older drugs such as 5‐fluorouracil, are used as inhibitors of different enzymes in the folate pathway necessary for the synthesis of pyrimidine nucleotides. Cytosine arabinoside and more recent compounds like gemcitabine, fludarabine, cladribine, and pentostatin inhibit DNA polymerase action during DNA synthsis. The potent activity of natural products such as doxorubicin also led to the development of the synthetic topoisomerase inhibitors that are now another important group of drugs targeted at DNA. The increasing power of organic chemistry increasingly allows the synthesis of close analogs of cytotoxic, but complex, natural products as potential drugs; recent examples are synthetic analogs of the duocarmycins and the epothilones. Finally, an increasing understanding of tumor physiology and genetics has allowed the development of tumor‐activated prodrugs of DNA‐active agents. Using hypoxia, gene therapy, or antibody targeting to activate such prodrugs specifically in tumor tissue has the potential to increase the therapeutic index of these agents by limiting the exposure of sensitive non‐tumor cell populations.
Advances and challenges in flash flood warnings (2007)

(2007). Advances and challenges in flash flood warnings. Environmental Hazards: Vol. 7, No. 3, pp. 173-178.
Chemoenzymatic Synthesis of 7-Deaza Cyclic Adenosine 5‘-Diphosphate Ribose Analogues, Membrane-Permeant Modulators of Intracellular Calcium Release (2008)

An optimized synthetic route to 7-deaza-8-bromo-cyclic adenosine 5'-diphosphate ribose (7-deaza-8-bromo-cADPR 3), an established cell-permeant, hydrolysis-resistant cyclic adenosine 5'-diphosphate ribose (cADPR) antagonist, is presented. Using NMR analysis, we found that 3 adopted a C-2' endo conformation in the N9-linked ribose and a syn conformation about the N9-glycosyl linkage, which are similar to that of cADPR. The synthetic route was also employed to produce 7-deaza-2'-deoxy-cADPR 4, a potential cell-permeant cADPR analogue. 3 and 4 were more stable to chemical hydrolysis, consistent with the observation that 7-deaza-cADPR analogues are more stable than their parent adenosine derivatives. 3 was also found to be stable to enzyme-mediated hydrolysis using CD38 ectoenzyme.
‘Phoenix’ reflectarray unit cell with reduced size and inductive loading (2016)

This study presents a new Phoenix unit cell with reduced size ( λ 0 /3 at centre frequency). Three different techniques are investigated to preserve a complete 360° phase range, with quasi‐linear and parallel phase responses over a reasonable frequency band, in spite of this small size. The phase cycle successively uses two different printed elements with complementary capacitive and inductive responses. The studied techniques aim at increasing the insufficient inductive effect. As a demonstration, a 1877‐element reflectarray is fabricated with the technique compatible with a single‐substrate fabrication process. Measured results show a 1 dB gain bandwidth of 11.3%.
Design of passive chipless wireless motion sensor using dual polarization effect (2017)

This paper presents a new principle of a passive chipless RFID wireless sensor for a rotational motion measurement and identification. The sensing and identification principles are based on a high quality factor substrate integrated cavity (SIW) resonator with dual antennas at two different angles. Depending on the angle difference between the dual antennas, the backscattered power generates a unique and identifiable pattern, which encodes in time domain both the rotational speed and the signature code of the rotating object. By the utilization of different dual polarizations, different sensor tags can be created with identification capabilities allow to distinguish between different sensors. The sensor operation principle has been investigated and analyzed experimentally for determining maximum number of possible codes using the response time of the reader. The choice of SIW for proposed sensor tag principle has the advantages of having high quality factor, low insertion loss, and high power capability as well as compatibility with planar microwave circuit technology.
PYROLYSIS OF EMPTY FRUIT BUNCHES: INFLUENCE OF TEMPERATURE ON THE YIELDS AND COMPOSITION OF GASEOUS PRODUCT (2014)

With the increasing concern on fossil fuel depletion and environmental problems, the utilization of renewable biomass resources is expected to play an important role in the future. Biomass can be converted into a variety of fuels and chemicals by different processes; one of which is pyrolysis that has been subjected to extensive research in recent years. In this study, pyrolysis of oil palm Empty Fruit Bunches (EFB) was investigated using a quartz fluidised-fixed bed reactor. The effects of pyrolysis temperatures on the yields and composition of gaseous products were investigated. The temperatures of pyrolysis used were in the range of 300-600C. The gaseous products from pyrolysis of (EFB) were analyzed using a dual-channel micro-GC with Thermal Conductivity Detector (TCD). The highest and lowest gas yields obtained were 42.98 and 31.55% at 600 and 300C, respectively. The gases detected were Carbon Monoxide (CO), carbon dioxide (CO 2 ), Methane (CH 4 ), Ethane (C 2 H 6 ) and Ethylene (C 2 H 4 ). At 300 and 400C, the gas mixture comprised mainly CO 2 (20%) and CO (20%). Other gases such as CH 4 , C 2 H 4 and C 2 H 6 only evolved at higher temperature starting from 400C with the yield of the latter two gases in very low concentration.
Multi-tapped magnetoresistive heads for magnetic tape tracking servo (1998)

A multi-tapped magnetoresistive (MR) stripe has been commercially fabricated as a tape head for evaluation as a potential tracking sensor for magnetic tape systems with dedicated servo. In this approach, two adjacent MR elements sharing a common bias current are each positioned halfway over a single 17.5 /spl mu/m wide servo track. The head leads provide signals from each of the MR elements which are separated 1.25 /spl mu/m by permanent magnets that provide longitudinal bias. Since this servo configuration uses a differential sensor with a simple square wave tracking pattern, the system can allow self servo formatting. The evaluation of these heads on a Metrum test stand with 1550 Oe Sony MP media has revealed a number of important features to consider in using such a head. On-track isolated transition responses of the multi-tapped elements are shown to be comparable to those from standard individual MR heads fabricated on the same wafer. Cross-track signal profiles show that two adjacent elements in the multi-tapped head can provide an approximately linear tracking error signal within /spl plusmn/4 /spl mu/m of track center. Finally, sample position error signal results demonstrate the potential of this type of servo scheme.
The Risk of Virologic Failure Decreases with Duration of HIV Suppression, at Greater than 50% Adherence to Antiretroviral Therapy (2009)

The risk of virologic failure for adherence greater than 50% declines with longer duration of continuous suppression. While high adherence is required to maximize the probability of durable viral suppression, the range of adherence capable of sustaining viral suppression is wider after prolonged periods of viral suppression.
DOES REDUCING HYPERURICEMIA REDUCE BLOOD PRESSURE IN HYPERTENSION WITH HYPERURICEMIA? (2004)

Osaka University Graduate School of Medicine (Mikami) Sepulveda VA Medical Center and UCLA School of Medicine (Ogihara) (Tuck) Osaka University Graduate School of Medicine (Masuo)
Synthesis and Photodynamics of Fluorescent Blue BODIPY-Porphyrin Tweezers Linked by Triazole Rings (2012)

Novel zinc porphyrin tweezers in which two zinc porphyrins were connected with π-conjugated boron dipyrromethenes (BDP meso-Por(2) and BDP β-Por(2)) through triazole rings were synthesized to investigate the photoinduced energy transfer and electron transfer. The UV-vis spectrum of BDP β-Por(2) which has less bulky substituents than BDP meso-Por(2) exhibits splitting of the Soret band as a result of the interaction between porphyrins of BDP β-Por(2) in the excited state. Such interaction between porphyrins of both BDP β-Por(2) and BDP meso-Por(2) is dominant at room temperature, while the coordination of the nitrogen atoms of the triazole rings to the zinc ions of the porphyrins occurs at low temperature. The conformational change of the BDP-porphyrin composites was confirmed by the changes in UV-vis and fluorescence spectra depending on temperature. Photodynamics of BDP meso-Por(2) and BDP β-Por(2) has also been investigated by laser flash photolysis. Efficient singlet-singlet energy transfer from the ZnP to the π-conjugated BDP moiety of both BDP meso-Por(2) and BDP β-Por(2) occurred in opposite direction as compared to energy transfer from conventional BDP to ZnP due to the π-conjugation in nonpolar toluene. In polar benzonitrile, however, additional electron transfer occurred along with energy transfer.
Nitric oxide and bleeding time. (1994)

Abman, Kinsella, and co-workers caution against the widespread use of nitric oxide (NO) gas in the neonatal intensive care unit.1,2 However, like other leading advocates of NO therapy, they limit their remarks concerning toxicology to a discussion of the risks of acute lung injury and methemoglobinemia. It must be remembered that NO may have other important side effects as well. In particular, NO inhalation in concentrations of 30 ppm prolongs bleeding time in rabbits and humans,3 making it a uniquely dangerous agent for use in preterm infants at risk for intraventricular hemorrhage.
On the impact of dishing in metal CMP processes on circuit performance (2002)

In this paper, we explore the impact of dishing in metal CMP processes on circuit performance. The impact on power distribution networks and clock distribution networks, critical components in modern VLSI designs, is of specific interest. For the two examples given in this paper, we find the impact to be very small.
Multisensory Home-Monitoring in Individuals With Stable Chronic Obstructive Pulmonary Disease and Asthma: Usability Study of the CAir-Desk (2022)

The CAir-Desk showed favorable technical performance and was well-accepted by our sample of participants with stable COPD and asthma. The obtained insights were used in a redesign of the CAir-Desk, which is currently applied in a randomized controlled trial including an interventional program.
Abstract IA03: Engineering artificial antigen presenting cells, aAPC, for cancer immunotherapy: From bench to bedside (2021)

Abstract Adoptive Cellular Therapies, ACT, are promising immunotherapeutic approaches for treatment of cancer that, clinically, have had significant successes and yet many challenges remain that prevent ACT approaches from becoming front line therapy. In this presentation we will discuss the challenges associated with current approaches and show how artificial Antigen Presenting Cells, aAPC-based approaches help overcome those challenges. Thus, aAPC based approaches represent an off-shelf, scalable approach to production of clinical scale and grade T cells for the adoptive immunotherapy of cancer. Citation Format: Jonathan P. Schneck. Engineering artificial antigen presenting cells, aAPC, for cancer immunotherapy: From bench to bedside [abstract]. In: Abstracts: AACR Virtual Special Conference: Tumor Immunology and Immunotherapy; 2020 Oct 19-20. Philadelphia (PA): AACR; Cancer Immunol Res 2021;9(2 Suppl):Abstract nr IA03.