gebhart/patrepeval huggingface dataset:
Numerical parametric lens for shifting, magnification, and complete aberration compensation in digital holographic microscopy (2006)

The concept of numerical parametric lenses (NPL) is introduced to achieve wavefront reconstruction in digital holography. It is shown that operations usually performed by optical components and described in ray geometrical optics, such as image shifting, magnification, and especially complete aberration compensation (phase aberrations and image distortion), can be mimicked by numerical computation of a NPL. Furthermore, we demonstrate that automatic one-dimensional or two-dimensional fitting procedures allow adjustment of the NPL parameters as expressed in terms of standard or Zernike polynomial coefficients. These coefficients can provide a quantitative evaluation of the aberrations generated by the specimen. Demonstration is given of the reconstruction of the topology of a microlens.
The effect of amino acid derivative of clofibric acid (WKLB-5), and theophylline monoester of nicotinic acid (ME1) on the development of experimental atherosclerosis in rabbits. (1986)

In order to determine the efficacy of new compounds--an amino acid derivative of clofibric acid (WKLB-5), and a theophylline monoester of nicotinic acid (ME1)--a high fat diet (HFD) was applied to rabbits for 3 months, with or without the above mentioned compounds. The HFO included coconut oil, cholesterol and cholic acid. A substantial hypolipemic activity of those compounds was demonstrated; however, the studied lipid fractions did not undergo normalization, except FFA whose level after ME1 administration was distinctly lower than in control animals. Sudanophilic changes were found on 83% of surface of the interior membrane of aorta in rabbits kept on the HFD only, on 35% of surface--in rabbits treated with the HFD + WKLB-5, and on 75% of surface--in rabbits treated with the HFD + ME1. Thus in those animals no parallelism between the hypolipemic and antiatherosclerotic activities was observed.
Characterization of Electronic and Ionic Transport in Li1-xNi0.8Co0.15Al0.05O2(NCA) (2015)

Despite the extensive commercial use of Li <sub>1-x</sub>Ni <sub>0.8</sub>Co <sub>0.15</sub>Al <sub>0.05</sub>O <sub>2</sub> (NCA) as the positive electrode in Li-ion batteries, and its long research history, its fundamental transport properties are poorly understood. These properties are crucial for designing high energy density and high power Li-ion batteries. Here, the transport properties of NCA are investigated using impedance spectroscopy and dc polarization and depolarization techniques. The electronic conductivity is found to increase with decreasing Li-content from ∼10 <sup>-4</sup> Scm <sup>-1</sup> to ∼10 <sup>-2</sup> Scm <sup>-1</sup> over x = 0.0 to 0.6, while lithium ion conductivity is at least five orders of magnitude lower for x = 0.0 to 0.75. A surprising result is that the lithium ionic diffusivity vs. x shows a v-shaped curve with aminimum at x=0.5, while the unit cell parameters show the opposite trend. This suggests that cation ordering has greater influence on the composition dependence than the Li layer separation, unlike other layered oxides. From temperature-dependent measurements in electron-blocking cells, the activation energy for lithium ion conductivity (diffusivity) is found to be 1.25 eV (1.20 eV). Chemical diffusion during electrochemical use is limited by lithium transport, but is fast enough over the entire state-of-charge range to allow charge/discharge of micron-scale particles at practical C-rates.
Palladium-catalysed direct arylation of a tris-cyclometallated Ir(iii) complex bearing 2,2′-thienylpyridine ligands: a powerful tool for the tuning of luminescence properties (2011)

Palladium-catalysed direct 5-arylation of metallated thiophenes of fac-Ir(N^C(3')-thpy)(3) with aryl bromides via C-H bond functionalisation allows the synthesis of a variety of new Ir complexes in only one step (thpyH = 2,2'-thienylpyridine). The method offers simple modification of the nature of the ligand and hence of the photophysical properties of such complexes.
Block permutations in Boolean Space to minimize TCAM for packet classification (2012)

Packet classification is one of the major challenges in designing high-speed routers and firewalls as it involves sophisticated multi-dimensional searching. Ternary Content Addressable Memory (TCAM) has been widely used to implement packet classification thanks to its parallel search capability and constant processing speed. However, TCAM-based packet classification has the well-known range expansion problem, resulting in a huge waste of TCAM entries. In this paper, we propose a novel technique called Block Permutation (BP) to compress the packet classification rules stored in TCAMs. The compression is achieved by performing block-based permutations on the rules represented in Boolean Space. We develop an efficient heuristic approach to find the permutations for compression and design its hardware implementation. Experiments on ClassBench classifiers and ISP classifiers show that the proposed BP technique can reduce TCAM entries by 53.99% on average.
Fluorous Scavengers (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.
Abstract 4873: ImmTACs re-direct the immune system efficiently to eradicate cancer (2016)

Abstract Immunotherapy strategies that are able to induce T cell infiltration into tumors and activate a cytotoxic T cell response have the potential to destroy the tumor. Although T cells can mediate clearance of a tumor, thymic selection and the suppressive microenvironment limit their effectiveness. To overcome poor tumor immunogenicity, we have developed a unique platform that enables the generation of ImmTACs (Immune-mobilising monoclonal TCRs Against Cancer); these are comprised of an affinity enhanced TCR specific for a cancer antigen fused to an anti-CD3 scFv. The TCR end targets and binds MHC class I/peptide complex displayed on cancerous cells while the anti-CD3 scFv end engages polyclonal T cells to mediate a potent anti-tumor response. The most advanced ImmTAC, IMCgp100, targets the HLA-A2/gp100280-288 epitope presented by melanoma cells. IMCgp100 is currently in a Phase I/IIa clinical trial for advance malignant melanoma and is showing promising clinical efficacy in some patients. Here we report a series of in vitro experiments evaluating IMCgp100 mechanism of action. IMCgp100 is able to redirect T cells from healthy donors or from melanoma patients to destroy cancer cells and secrete a range of inflammatory cytokines and chemokines associated with T cell trafficking into tumors; some of these cytokines also induce upregulation of inhibitory pathway molecules. We show that effector memory cells in the CD8+ and CD4+ T cell compartments are very efficient in eliminating melanoma cells and in expanding upon IMCgp100 engagement. The effects of combining IMCgp100 with agents that relieve the suppression imposed by immune check-point molecules have also been investigated. Citation Format: Giovanna Bossi, Rupert Kenefeck, Caroline Caroline Boudousquie, Jane Harper, Joseph Dukes, Nathaniel Liddy, Samantha Paston, Tara Mahon, Peter Molloy, Malkit Sami, Emma Baston, Brian Cameron, Annelise Vuidepot, Namir Hassan, Bent K. Jakobsen. ImmTACs re-direct the immune system efficiently to eradicate cancer. [abstract]. In: Proceedings of the 107th Annual Meeting of the American Association for Cancer Research; 2016 Apr 16-20; New Orleans, LA. Philadelphia (PA): AACR; Cancer Res 2016;76(14 Suppl):Abstract nr 4873.
ChemInform Abstract: Trifluoromethyl vs. Methyl Ability to Direct Enantioselection in Microbial Reduction of Carbonyl Substrates. (1998)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Intermediate-Term Outcomes of Endoscopic or Open Vein Harvesting for Coronary Artery Bypass Grafting (2021)

This randomized clinical trial examines intermediate-term outcomes of endoscopic vs open vein harvesting for coronary artery bypass grafting as part of the Randomized Endo-Vein Graft Perspective (REGROUP) trial.
Abstract 12655: Cardiac Pacing Alters Neural Information Processing in the Intrinsic Cardiac Nervous System (2014)

Introduction: Cardiac pacing is an established therapy; however, it may have detrimental effects on cardiac neurohumoral control. We investigated the effects of pacing on the intrinsic cardiac nervous system (ICNS), an important coordinator of regional cardiac function. Methods: Activity from intrinsic cardiac (IC) neurons in the ventral interventricular ganglionated plexus (VIV GP) was recorded using a linear microelectrode array in 5 normal pigs. Changes in IC activity were evaluated in response to epicardial pacing (current: 6 mA; pulse width: 2 ms) at 10% above resting heart rate at the following sites: (1) right atrial appendage (RAA), (2) right ventricular (RV) apex, and (3) left ventricular (LV) posterolateral wall. Results: A total of 72 IC neurons were identified. The proportion of neurons responding to pacing was 23% at RAA, 27% at RV apex, and 27% at LV posterolateral wall. Pacing at each site caused significant activation (p &lt; 0.01), significant suppression (p &lt; 0.01), or no change in firing rate of different subsets of neurons. Of all sites, the largest change in firing rate from basal activity was at the LV posterolateral wall, with a significant increase of 1.38 Hz (p &lt; 0.01) in neurons activated by pacing and a significant decrease of 0.63 Hz (p &lt; 0.01) in those suppressed by pacing (Figure 1). There was also a significant difference in basal activity between neurons activated by pacing versus those suppressed by pacing (p &lt; 0.01). Conclusions: Our results suggest that pacing has a site-dependent effect on the ICNS. We observed effects with both atrial and ventricular pacing and that LV posterolateral pacing has the greatest impact on neural activity in the VIV GP. Also, neurons with low levels of basal activity tended to be activated by pacing, and those with high levels of basal activity tended to be suppressed, indicating a state-dependent effect. Modulation of information processing in the ICNS may provide the link between pacing and neuroendocrine activation.
Enhanced Graphene Photodetector with Fractal Metasurface (2016)

We designed and fabricated a broadband, polarization-independent photodetector by integrating graphene with a fractal Cayley tree metasurface. Our measurements show an almost uniform, tenfold enhancement in photocurrent generation due to the fractal metasurface structure.
Supplementary Figure 1B from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses (2023)

Supplementary Figure 1B from Depletion of Peripheral Macrophages and Brain Microglia Increases Brain Tumor Titers of Oncolytic Viruses
A Compact Human-Powered Energy Harvesting System (2018)

A fully functional, self-sufficient body-worn energy harvesting system is presented in this paper. The system is designed for passively capturing energy from human motion, with the long-term vision of supplying power to portable, wearable, or even implanted electronic devices. Compared with state-of-the-art vibrational systems, the system requires no external power supplies and can bootstrap from zero-state-of-charge to generate electrical energy from walking, jogging, and cycling; convert the induced AC voltage to DC voltage; and then boost and regulate the DC voltage to charge a Li-ion-polymer battery. Measurements show that at open-load the system turns on when the input is above 1 V pk and turns off when the input drops below about 600 mV pk with no measurable standby power consumption. Tested under normal human activities (walking, jogging, and cycling) when worn on different parts oze body, the 70 cm 3 system is shown to charge a 3.7 V rechargeable battery at charge rates ranging from 33 W to 234 W.
A flexible organic active matrix circuit fabricated using novel organic thin film transistors and organic light-emitting diodes (2010)

We present an active matrix circuit fabricated on plastic (polyethylene naphthalene, PEN) and glass substrates using organic thin film transistors and organic capacitors to control organic light-emitting diodes (OLEDs). The basic circuit is fabricated using two pentacene-based transistors and a capacitor using a novel aluminum oxide/parylene stack (Al2O3/ parylene) as the dielectric for both the transistor and the capacitor. We report that our circuit can deliver up to 15 μA to each OLED pixel. To achieve 200 cd m-2 of brightness a 10 μA current is needed; therefore, our approach can initially deliver 1.5× the required current to drive a single pixel. In contrast to parylene-only devices, the Al2O 3/parylene stack does not fail after stressing at a field of 1.7 MV cm-1 for &amp;gt;10 000 s, whereas 'parylene only' devices show breakdown at approximately 1000 s. Details of the integration scheme are presented. © 2010 IOP Publishing Ltd.
‘The ground on which Rational Christianity may firmly take its stand’ (2015)

Abstract This chapter explores the historical criticism of the Bible in the mid-nineteenth century. Orthodox Dissenters initially felt that the foundations of their faith were threatened to a much greater extent by biblical criticism, rather than the evolutionary theories of the geologists and biologists. Few Nonconformists knew much about geology and fewer still had a working knowledge of biology, and at first the orthodox could take comfort in the sheer incredibility of Darwin's hypothesis. By contrast, tens of thousands of nineteenth-century Nonconformists, lay as well as ministerial, had an intimate knowledge of the books of both the Old and the New Testaments, and any challenge to their authority was recognized as a more immediate and a more plausible threat to their faith. The threat initially came from German scholars who cast doubt on the historical reliability of the Bible. In England, the Unitarians were the most willing to embrace the new ideas of the German higher critics.
On-Line Emission Analysis of Polycyclic Aromatic Hydrocarbons down to pptv Concentration Levels in the Flue Gas of an Incineration Pilot Plant with a Mobile Resonance-Enhanced Multiphoton Ionization Time-of-Flight Mass Spectrometer (1998)

A newly developed, mobile laser mass spectrometer (resonance-enhanced multiphoton ionization - time-of-flight mass spectrometer, REMPI-TOFMS) was applied to on-line measurements at a waste incineration pilot plant. REMPI-TOFMS combines the optical selectivity of resonance-enhanced multiphoton ionization with a time-of-flight mass analysis to give a two-dimensional analytical method. Special care was taken to build up a sampling and inlet system suitable for on-line measurements of large, semivolatile polycyclic aromatic hydrocarbons (PAHs). An effusive molecular beam inlet in combination with a fixed frequency UV laser (Nd:YAG at 266 nm or KrF excimer at 248 nm) was used. Under these conditions, many different PAHs can be ionized selectively from the complex flue gas matrix. For example, the achieved detection limit for naphthalene is in the 10 parts-per-trillion by volume (pptv) concentration range. Calibration was performed by using external concentration standards supplied in low ppbv concentrations. The instrumentation is sufficiently robust to be operated under industrial conditions at incineration plants, for instance. The REMPI mass spectra can be acquired at 5-50 Hz. Time profiles of the concentrations of different PAHs in the flue gas were monitored with a time resolution of 200 ms. Significant variations in the concentration profile of several PAHs up to mass 276 amu (e.g., benzo[ghi]perylene) and methylated PAHs have been observed while combustion parameters were changing. In summary, it was demonstrated that laser mass spectrometry (REMPI-TOFMS) enables a real-time on-line trace analysis of combustion flue gases or industrial process gases.
Biocompatibility Assessment of the First Generation PediaFlow Pediatric Ventricular Assist Device (2010)

The PediaFlow pediatric ventricular assist device is a miniature magnetically levitated mixed flow pump under development for circulatory support of newborns and infants (3-15 kg) with a targeted flow range of 0.3-1.5 L/min. The first generation design of the PediaFlow (PF1) was manufactured with a weight of approximately 100 g, priming volume less than 2 mL, length of 51 mm, outer diameter of 28 mm, and with 5-mm blood ports. PF1 was evaluated in an in vitro flow loop for 6 h and implanted in ovines for three chronic experiments of 6, 17, and 10 days. In the in vitro test, normalized index of hemolysis was 0.0087 ± 0.0024 g/100L. Hemodynamic performance and blood biocompatibility of PF1 were characterized in vivo by measurements of plasma free hemoglobin, plasma fibrinogen, total plasma protein, and with novel flow cytometric assays to quantify circulating activated ovine platelets. The mean plasma free hemoglobin values for the three chronic studies were 4.6 ± 2.7, 13.3 ± 7.9, and 8.8 ± 3.3 mg/dL, respectively. Platelet activation was low for portions of several studies but consistently rose along with observed animal and pump complications. The PF1 prototype generated promising results in terms of low hemolysis and platelet activation in the absence of complications. Hemodynamic results validated the magnetic bearing design and provided the platform for design iterations to meet the objective of providing circulatory support for young children with exceptional biocompatibility.
Spatial and spectral imaging of LMA photonic crystal fiber amplifiers (2011)

We demonstrate modal characterization using spatial and spectral resolved (S<sup>2</sup>) imaging, on an Ytterbium-doped large-mode-area photonic crystal fiber (PCF) amplifier and compare results with conventional cut-off methods. We apply numerical simulations and step-index fiber experiments to calibrate our mathematical and experimental routines of our S<sup>2</sup> imaging system. We systematically analyze higher order mode (HOM) content of a polarizing 40&mu;m core double-clad PCF amplifier with various launching and coiling configurations. We demonstrate a HOM suppression of more than -24dB with variance of 2.3dB.
Efficient Greenish Blue Electrochemiluminescence from Fluorene and Spirobifluorene Derivatives (2012)

The spectroscopic and electrochemical behavior as well as electrogenerated chemiluminescence (ECL) of a series of donor-π-donor derivatives bearing triphenylamine groups as donor connected to a fluorene, 2,7-bis-(4-(N,N-diphenylamino)phen-1-yl)-9,9'-dimethylfluorene (1), or spirobifluorene core, 2,7-bis-(4-(N,N-diphenylamino)phen-1-yl)-9,9'-spirobifluorene (2) and 2,2',7,7'-tetrakis(4-(N,N-diphenylamino)phen-1-yl)-9,9'-spirobifluorene (3), were investigated. Besides a high photoluminescence (PL) quantum yield in solution (between 81 and 87%), an efficient radical ions annihilation process induces intense greenish blue ECL emission that could be seen with the naked eye. Only the tetrasubstituted spirobifluorene derivative (compound 3) shows weak ECL obtained by a direct annihilation mechanism. Because the energy of the annihilation reaction is higher than the energy required to form the singlet excited state, the S-route could be considered the pathway followed by the ECL process in these molecules. The ECL emissions recorded by direct ion-ion annihilation show two bands compared to the single structureless PL band. The ECL spectra obtained by a coreactant approach using benzoylperoxide as a coreagent show no differences relative to that produced by annihilation, except for an increasing of ECL intensity for all compounds.
Experience-dependent perceptual grouping and object-based attention. (2002)

Earlier studies have shown that attention can be directed to objects, defined on the basis of generic grouping principles, highly familiar shapes, or task instructions, rather than to contiguous regions of the visual field.The 4 experiments presented in this article extend these findings, showing that object attention benefits-shorter reaction times to features appearing on a single object-apply to recently viewed novel shapes.One experiment shows that object attention operates even when the visible fragments correspond to objects that violate standard completion heuristics.Other experiments show that experience-dependent object benefits can apply to fragments even without evidence of occlusion.These results attest to the flexible operation of the perceptual system, adapting as a function of experience.
Evolution of an Indian Hero in France (2010)

…the great metropolis of the Northwest stands as a monumental token of the faith and friendship of Chief Se-at-tlh, for that was his name.
Expression and Modulation of an Invertebrate Presynaptic Calcium Channel α1 Subunit Homolog (2003)

Here we report the first assessment of the expression and modulation of an invertebrate alpha1 subunit homolog of mammalian presynaptic Cav2 calcium channels (N-type and P/Q-type) in mammalian cells. Our data show that molluscan channel (LCav2a) isolated from Lymnaea stagnalis is effectively membrane-targeted and electrophysiologically recordable in tsA-201 cells only when the first 44 amino acids of LCav2a are substituted for the corresponding region of rat Cav2.1. When coexpressed with rat accessory subunits, the biophysical properties of LCav2a-5'rbA resemble those of mammalian N-type calcium channels with respect to activation and inactivation, lack of pronounced calcium dependent inactivation, preferential permeation of barium ions, and cadmium block. Consistent with reports of native Lymnaea calcium currents, the LCav2a-5'rbA channel is insensitive to micromolar concentrations of omega-conotoxin GVIA and is not affected by nifedipine, thus confirming that it is not of the L-type. Interestingly, the LCav2a-5'rbA channel is almost completely and irreversibly inhibited by guanosine 5'-3-O-(thio)triphosphate but not regulated by syntaxin1, suggesting that invertebrate presynaptic calcium channels are differently modulated from their vertebrate counterparts.
Bioinspired Microfluidic Cooling (2018)

This chapter reviews various bioinspired approaches for the design of fluidic networks in wearable and architectural applications that have common elements to the fluidic mechanisms for biological thermal management. Fluidic cooling mechanisms for building windows can also benefit solar panel design. The chapter summarizes common manufacturing methods for wearable and architectural fluidic designs over large areas, where there are differing general requirements for scale, cost, contained flow, wearability, and mechanical flexibility. The fluidic designs for thermal management of buildings can be generally grouped into three main types: (i) thermal storage in fluidic layers, (ii) forced convection for thermal control, and (iii) fluidic networks for adaptive windows. The chapter also summarizes some of the fabrication methods for larger fluidic networks. It presents a review of various bioinspired approaches for the design of fluidic networks in wearable and architectural applications.
Ultra-low temperature synthesis of Ge-based optical materials and devices on Si using GeH3Cl (2022)

CMOS-compatible GeH 3 Cl is used to develop GeSn semiconductors and Ge/Si photodiodes. Responsivities of the latter display near ideal 0.95 collection efficiency (green) a performance improvement to devices made by other methods such as Ge 4 H 10 (black).