gebhart/patrepeval huggingface dataset:
Energy transfer between slowly moving atoms—the case of no crossing point (1976)

The classical path treatment of a collision between an excited atom and another atom with a nearly resonant energy level leads to coupled differential equations which have been discussed previously by many workers. Here we present an elementary procedure for solving this system of equations in the case of no crossing point and in the limit where $\ensuremath{\Delta}E\ensuremath{\tau}\ensuremath{\gg}\ensuremath{\hbar}$, with $\ensuremath{\Delta}E$ being the energy discrepancy and $\ensuremath{\tau}=\frac{b}{v}$ being a measure of the time of collision. Even though the method is designed to take advantage of the slowness of the collision, it is also shown to be exact if $\ensuremath{\Delta}E=0$. The form of the solution is very similar to that of Vainshtein et al., but the present derivation avoids several of their approximations which individually are not as accurate as their final result. It is also pointed out that the coupled equations which arise for the energy-transfer problem also arise in connection with the interaction of laser pulses with atoms. Hence, the method has application to a wide class of multistate problems. A simple laser-interaction problem is discussed as a second example of the method.
Biosynthesis of the antibiotic maduramicin. Origin of the carbon and oxygen atoms as well as the 13C NMR assignments. (1984)

The biosynthesis of maduramicin alpha and beta in a culture of Actinomadura yumaensis has been studied using 13C, 14C and 18O labeled precursors. The alpha component of this recently discovered polyether antibiotic, containing forty-seven carbon atoms in a seven-ring system, is derived from eight acetate, seven propionate and four methionine molecules. The beta component which is missing one methoxy group incorporates three methionine methyl groups. The carbohydrate moiety was enriched by methionine, but not significantly by acetate or propionate. Studies of the incorporation of 13C labeled precursors permit the 13C NMR assignment of maduramicin. The origin of oxygen atoms of maduramicin has been examined by feeding [1-13C, 18O2]acetate and [1-13C, 18O2]propionate separately in the fermentation culture and the resulting doubly labeled maduramicin samples were analyzed by the isotopic shifts in the 13C NMR spectra. These results are consistent with the initial formation of a triene, which is converted to maduramicin by cyclization of the triepoxide.
Advances in the Vinylogous Mukaiyama Aldol Reaction and Its Application to the Synthesis of the C1—C7 Subunit of Oleandolide. (2002)

Abstract For Abstract see ChemInform Abstract in Full Text.
Optimization of the performance of bulk NiO catalyst in the oxidative dehydrogenation of ethane by tuning the synthesis parameters (2022)

Highly stable and selective bulk NiO catalysts have been synthesized for the oxidative dehydrogenation (ODH) of ethane to ethylene. Interestingly, by optimizing synthesis parameters such as the amount of oxalic acid in the synthesis gel and the calcination temperature, undoped NiO catalysts have shown a consistent selectivity to ethylene of ca. 75%. The optimal catalyst requires the presence of a certain amount of oxalic acid in the synthesis gel and a final calcination at low temperatures (i.e. 350 °C). These catalysts have been deeply characterized by means of XRD, TPR, HRTEM, Raman and UV–vis diffuse reflectance spectroscopies, XPS and Electrochemical Impedance Spectroscopy measurements and tested in the ethane ODH. A novel electrochemical study has been undertaken, showing the p-character of all the NiO catalysts synthesized but differing in their capacitance values and density of cationic vacancies. The catalytic performance of NiO catalysts has been explained in terms of the different physicochemical properties (including changes in the number of vacancies) of the samples and the isolation of electrophilic oxygen species.
Prediction of tantalum microstructure evolution during thermomechanical treatments using FEM calculations with a dislocation density based constitutive law (2008)

In this paper, the behaviour of the tantalum subjected to a complex range of thermomechanical solicitations is studied and modelled. The objective of this work is the prediction of microstructure evolution of a tantalum part that is cold flow-formed, then stress-relieved and softened by heat treatments. Flow forming is a cold chipless process that elongates and thins the wall of a tubular part by applying a free rotating roller on the wall of the rotating part. (See Figure 1) This process leads to large strain up to 5 and one material point may be deformed at a fluctuating strain rate. To model this process, it is thus recommended to use a constitutive law that takes into account the history of the material. Microstructure evolution is controlled through the whole process by monitoring the state variable, that is, the dislocation density, within a FEM code. The 3D FEM software FORGE2007® is used to model the entire process. The code is enhanced with physical constitutive laws relative to the tantalum and derived from works of Klepaczko and Buy et al. [1,2,3]. The formalism of Klepaczko and Buy et al. is useful since it is based on laws regulating physical mechanisms of dislocations multiplication, annihilation and kinetics of glide depending on strain rate and thermal activation. Static recovery is modelled subsequently with an incremental approach where the softening is related to the dislocation density evolution. A set of thermomechanical experiments and treatments are done to identify the constitutive law and associated microstructure evolution. Compression, dynamic and static torsion tests covering a wide range of strain rates are used to fit the mechanical constitutive law and the dislocation density evolution law both inspired from Klepaczko and Buy et al. works. The same samples are then annealed with variable temperatures and times. Microstructure of annealed samples is characterized by means of micro-hardness. They give information to evaluate the dislocation density evolution. The data is used to model static recovery.0.
Author response: USP28 deletion and small-molecule inhibition destabilizes c-MYC and elicits regression of squamous cell lung carcinoma (2021)

Deletion and small-molecule inhibition of ubiquitin-specific protease 28 destabilizes the oncogenes c-MYC, c-JUN, and Δp63, and elicits regression of squamous cell lung carcinoma, a major cancer type with currently limited treatment options.
Dietary Supplementation of Gingerols- and Shogaols-Enriched Ginger Root Extracts Attenuate Pain-Associated Behaviors in Animals with Spinal Nerve Ligation (2020)

Neuropathic pain (NP), arising from damage to the nervous system, could be a consequence of the imbalance between reactive oxygen species (ROS) and endogenous antioxidants after nerve injury, leading to neuroinflammation. Therefore, this study was to evaluate the effects of two ginger root extracts rich in gingerols and shogoals, respectively, on pain sensitivity and anxiety-like behaviors in neuropathic animals. We also assessed the plasma circulating cell-free mitochondrial DNA (ccf-mtDNA) damage, a biomarker of excessive mitochondria-derived ROS linked to inflammation. Sixteen male rats were randomly divided into 4 groups: sham group, spinal nerve ligation (SNL) group as the pain control group, SNL+ gingerols-enriched ginger (GEG) extract group, and SNL+ shogoals-enriched ginger (SEG) extract group. Animals in GEG and SEG groups were fed with their respective diets on the day of SNL surgery for 30 days. At 1 day before and 10, 20, and 30 days post operation, (i) paw withdrawal mechanical thresholds were measured using von Frey filaments for pain sensory assessment; and (ii) center frequency and center duration in the open field test (OFT) were measured to assess anxiety-like behavior. At Day 30, plasma was obtained for ccf-mtDNA concentration measurement. Data were analyzed by one-way ANOVA or one-way repeated measures analysis of variance follow by post-hoc analysis. Compared to the sham group, the SNL group had significant greater pain sensitivity to mechanical stimuli. When compared to the SNL group, both GEG and SEG groups showed significantly (50%) reduced pain sensitivity (increased thresholds) as early as at 10 days and sustained at 30 days. Relative to the SNL group, both GEG and SEG groups also had less anxiety-like behavior (as indicated by the elongated center duration and increased center frequency in OFT). The SNL group had significantly higher plasma ccf-mtDNA levels relative to the sham group. When SNL-animals were fed a diet supplemented with either gingerols or shogaols, both groups showed reduction in plasma ccf-mtDNA. Both gingerols and shogaols supplementation decreased pain sensitivity and improved anxiety-like behavior mediated in part through the suppression of mitochondrial damage. Texas Tech University Health Sciences Center.
Heterogenous integrated silicon-photonic module for producing widely tunable narrow linewidth RF (2013)

Generating RF signals over the entire spectrum, from hundreds of MHz into the hundreds of GHz, has previously required the use of special oscillators designed only for specific bands of operation within that spectrum. An optoelectronic system based on side-band-injection-locked lasers is capable of generating RF frequencies tunable over a span of more than 7 octaves with extremely low phase noise. [1] Here we present the results of our efforts to develop a heterogeneously integrated version of this system based on a silicon-photonic integrated circuit coupled to III-V semiconductor gain chips. Towards that effort, we have successfully demonstrated an integrated module and shown tunable RF generation with a ~1 Hz linewidth.
Quasi Phase-Matched FOPA with 50 nm Gain Bandwidth Using Dispersion Stable Highly Nonlinear Fiber (2014)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text S. Takasaka, Y. Taniguchi, M. Takahashi, J. Hiroshi, M. Tadakuma, H. Matsuura, K. Doi, and R. Sugizaki, "Quasi Phase-Matched FOPA with 50 nm Gain Bandwidth Using Dispersion Stable Highly Nonlinear Fiber," in Optical Fiber Communication Conference, OSA Technical Digest (online) (Optica Publishing Group, 2014), paper W3E.2. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Influence of solvents on low-temperature reduction-exfoliation of graphene oxide (2017)

Graphene due to its extraordinary properties and a wide range of potential applications, has aroused a great interest. Although there are many ways to obtain graphene, the existing methods still possess certain disadvantages. Numerous attempts are made to scale up a new and efficient production method of this material on an industrial scale. A very popular method to obtain graphene is a two-step process. It is based on the oxidation of graphite and subsequent reduction to graphene. This article presents a new way of low-temperature reduction of graphene oxide (GO) in presence of various solvents. Indeed, using of appropriate organic solvents in a particular stage of graphene preparation affects the reduction process and the exfoliation of graphene oxide. The possibility to reduce GO in the presence of a disperser opens new paths for the preparation of graphene containing composites.
Plasma Inflammatory Biomarkers Are Associated With Poststroke Cognitive Impairment: The Nor-COAST Study (2023)

gov; Unique identifier: NCT02650531.
High Performance Green LEDs by Homoepitaxial (2009)

This work's objective was the development of processes to double or triple the light output power from green and deep green (525 - 555 nm) AlGaInN light emitting diode (LED) dies within 3 years in reference to the Lumileds Luxeon II. The project paid particular effort to all aspects of the internal generation efficiency of light. LEDs in this spectral region show the highest potential for significant performance boosts and enable the realization of phosphor-free white LEDs comprised by red-green-blue LED modules. Such modules will perform at and outperform the efficacy target projections for white-light LED systems in the Department of Energy's accelerated roadmap of the SSL initiative.
Multi-loop interactive control motivated by driver-in-the-loop vehicle dynamics controls: The framework (2009)

This paper studies a framework of controlling a system with multiple interactive control loops including a continuously activated primary loop and discretely activated secondary loops. The structure of the controller in the primary loop is unknown while its output is observable and the controllers in secondary loops are subject to design such that the control performance of the primary loop can be assisted when facing significant changes in the plant, the environment, and the control objective. Such a paradigm fits very well with driver-in-the-loop vehicle controls where the primary loop includes a driver while the secondary loops include electronic devices.
Complement Activation in 22q11.2 Deletion Syndrome (2020)

The 22q11.2 deletion syndrome (22q11.2 del), also known as DiGeorge syndrome, is a genetic disorder with an estimated incidence of 1:3000 to 1:6000 births. These patients may suffer from affection of many organ systems with cardiac malformations, immunodeficiency, hypoparathyroidism, autoimmunity, palate anomalies, and psychiatric disorders being the most frequent. The importance of the complement system in 22q11.2 del has not been investigated. The objective of this study was to evaluate the complement system in relation to clinical and immunological parameters in patients. A national cohort of patients (n = 69) with a proven heterozygous deletion of chromosome 22q11.2 and a group of age and sex matched controls (n = 56) were studied. Functional capacity of the classical, lectin, and alternative pathways of the complement system as well as complement activation products C3bc and terminal complement complex (TCC) were accessed and correlated to clinical features. All patients in our study had normal complement activation in both classical and alternative pathways. The frequency of mannose-binding lectin deficiency was comparable to the normal population. The patients had significantly raised plasma levels of C3bc and a slight, but not significant, increase in TCC compared with controls. This increase was associated with the presence of psychiatric disorders in patients. The present study shows no complement deficiencies in 22q11.2 deletion syndrome. On the contrary, there are signs of increased complement activation in these patients. Complement activation is particularly associated with the presence of psychiatric disorders.
P02-02. Analysis of antigen specific degranulation potentials using IL-12 or IL-28B during HIV DNA Vaccination (2009)

Background A number of studies have suggested that CD8 T cells play an important role in control of HIV/SIV replication. Recently, it has been shown that CD8 T cells taken from HIV-positive long term non-progressors are more efficiently cytotoxic than those from rapid progressors. We therefore endeavored to test vaccine adjuvants for their ability to generate antigen specific CD8 T cells with a significant capacity for cytolytic degranulation. The adjuvants tested for this purpose were IL-12 and IL-28B.
Robust Design and Model Validation of Nonlinear Compliant Micromechanisms (2006)

Although the use of compliance or elastic flexibility in microelectromechanical systems (MEMS) helps eliminate friction, wear, and backlash, compliant MEMS are known to be sensitive to variations in material properties and feature geometry, resulting in large uncertainties in performance. This paper proposes an approach for design stage uncertainty analysis, model validation, and robust optimization of nonlinear MEMS to account for critical process uncertainties including residual stress, layer thicknesses, edge bias, and material stiffness. A fully compliant bistable micromechanism (FCBM) is used as an example, demonstrating that the approach can be used to handle complex devices involving nonlinear finite element models. The general shape of the force-displacement curve is validated by comparing the uncertainty predictions to measurements obtained from in situ force gauges. A robust design is presented, where simulations show that the estimated force variation at the point of interest may be reduced from /spl plusmn/47 /spl mu/N to /spl plusmn/3 /spl mu/N. The reduced sensitivity to process variations is experimentally validated by measuring the second stable position at multiple locations on a wafer.
Demonstration of integrated optical path monitoring sub-system in CDCG-ROADM network (2014)

We developed an integrated optical path monitoring sub-system prototype that fully integrates three functions; FSK light label monitor, in-band OSNR monitor, as well as conventional optical channel monitor, and successfully demonstrated the monitor operations for 112 Gbps DP-QPSK signals.
Induction of G2/M Arrest of the Cell Cycle by Genistein in Human Bladder Carcinoma and Leukemic Cells (2006)

본 연구에서는 T24 인체방광암 및 U937 백혈병 세포의 증식에 미치는 genistein의 영향을 조사 하였다. Genistein이 처리된 T24 및 U937 세포는 처리 농도 의존적으로 세포의 증식이 현저히 감소되었으며 심한 형태적 변형이 동반되었으나, U937 세포에서 보다 높은 감수성을 보였다. 이러한 T24 및 U937 세포의 증식억제 및 형태 변형은 G2/M기의 세포주기 억제 및 apoptosis 유발과 연관성이 있음을 flow cytometry를 이용한 세포주기의 분석을 통하여 확인하였다. T24 세포에서 genistein에 의한 G2/M arrest는 cyclin A, cyclin B1 및 Cdc25C 등의 단백질 발현 감소와 연관성이 있었으나, 종양억제 유전자 p53 및 Cdk inhibitor p21의 발현에는 큰 변화가 없었다. U937 세포에서 genistein에 의한 G2/M arrest는 cyclin B1 및 p53 비의존적인 p21의 발현 증가와 연관성이 있었다. 이상의 결과들은 현재까지 거의 연구가 진행된 바 없는 인체방광암 및 백혈병 세포에서 genistein의 항암작용을 이해하는데 중요한 자료가 될 것이고 나아가 genistein을 포함한 그와 유사한 항암제 후보물질들의 연구에 있어서 기초 자료로서 사용될 수 있을 것으로 생각된다. Genistein, a natural isoflavonoid phytoestrogen, is a strong inhibitor of protein tyrosine kinase and DNA topoisomerase activities. There are several studies documenting molecular alterations leading to cell cycle arrest and induction of apoptosis by genistein as a chemopreventive agent in a variety of cancer cell lines; however, its mechanism of action and its molecular targets on human bladder carcinoma and leukemic cells remain unclear. In the present study, we have addressed the mechanism of action by which genistein suppressed the proliferation of T24 bladder carcinoma and U937 leukemic cells. Genistein significantly inhibited the cell growth and induced morphological changes, and induced the G2/M arrest of the cell cycle in both T24 and U937 cells with a relatively stronger cytotoxicity in U937. The G2/M arrest in T24 cells was associated with the inhibition of cyclin A, cyclin B1 and Cdc25C protein expression without alteration of tumor suppressor p53 and cyclin-dependent kinase (Cdk) inhibitor p21(WAF1/CIP1). However, the inhibitory effects of genistein on the cell growth of U937 cells were connected with a marked inhibition of cyclin B1 and an induction of Cdk inhibitor p21 proteins by p53-independent manner. These data suggest that genistein may exert a strong anticancer effect and additional studies will be needed to evaluate the different mechanisms between T24 and U937 cells.
Toward Federated-Learning-Enabled Visible Light Communication in 6G Systems (2022)

Visible light communication (VLC) technology was introduced as a key enabler for the next generation of wireless networks, mainly thanks to its simple and low-cost implementation. However, several challenges prohibit the realization of the full potential of VLC, namely, limited modulation bandwidth, ambient light interference, optical diffuse reflection effects, devices&#x0027; nonlinearity, and random receiver orientation. On the contrary, centralized machine learning (ML) techniques have demonstrated significant potential in handling different challenges related to wireless communication systems. Specifically, it has been shown that ML algorithms exhibit superior capabilities in handling complicated network tasks, such as channel equalization, estimation and modeling, resources allocation, and opportunistic spectrum access control, to name a few. Nevertheless, concerns pertaining to privacy and communication overhead when sharing raw data of the involved clients with a server constitute major bottlenecks in the implementation of centralized ML techniques. This has led to the emergence of a new distributed ML paradigm, namely federated learning (FL), which can reduce the cost associated with transferring raw data, and preserve privacy by training ML models locally and collaboratively at the clients&#x0027; side. Hence, it becomes evident that integrating FL into VLC networks can provide ubiquitous and reliable implementation of VLC systems. With this motivation, this is the first in-depth review in the literature on the application of FL in VLC networks. To that end, besides the different architectures and related characteristics of FL, we provide a thorough overview on the main design aspects of FL-based VLC systems. Finally, we also highlight some potential future research directions of FL that are envisioned to substantially enhance the performance and robustness of VLC systems.
Semantic graphics for more effective visual communication (2009)

Computers are becoming faster, smaller and more interconnected, creating a shift in their primary function from computation to communication. This trend is exemplified by ubiquitous devices such as mobile phones with cameras, personal digital assistants with video, and information displays in automobiles. As communication devices and viewing situations become more plentiful, we need imagery that facilitates visual communication across a wide range of display devices. In addition, producing effective and expressive visual content currently requires considerable artistic skill and can consume days. There is a growing need to develop new techniques and user interfaces that enhance visual communication, while making it fast and easy to generate compelling content. New algorithms in semantic graphics, i.e. combining concepts and methods from visual art, perceptual psychology, information processing, and cognitive science, help facilitate users in creating, understanding and interpreting computer imagery. In this talk, Vidya Setlur will present the usage of semantic graphics for various information visualization goals.
Reciprocating optical modulator using a resonant modulating electrode for generation of high-order double sideband components (2005)

We propose and demonstrate a reciprocating optical modulator having a phase-shifted fiber Bragg grating, a tunable fiber Bragg grating, and a resonant-type optical modulator. It enables effective generation of high-order double sideband components.
Concurrent Binding of Complexin and Synaptotagmin to Liposome-Embedded SNARE Complexes (2009)

Synaptotagmin and complexin regulate SNARE-mediated synaptic vesicle exocytosis. It has been proposed that complexin clamps membrane fusion and that Ca(2+)-synaptotagmin displaces complexin from SNARE complexes to relieve this clamping activity. Using a reconstituted system, we demonstrate that complexin and synaptotagmin simultaneously bind to neuronal SNARE complexes and that both apo-synaptotagmin and complexin inhibit SNARE-mediated membrane fusion. Moreover, the clamping ability of apo-synaptotagmin occluded the clamping activity of complexin until the arrival of a Ca(2+) trigger, at which point synaptotagmin accelerated fusion while high concentrations of complexin inhibited fusion. Thus, the inhibitory patterns of synaptotagmin and complexin are different, suggesting that SNAREs assemble into distinct states along the fusion pathway. These data also suggest that during synaptotagmin-regulated vesicle-vesicle fusion, complexin does not function as a fusion clamp that is relieved by Ca(2+)-synaptotagmin.