gebhart/patrepeval huggingface dataset:
Can umbilical cord blood‐derived progenitors behave like neural cells after exposure to neurogenic signals? (2003)

Previous studies have suggested that human umbilical cord blood (HUCB) may serve as a rich source of hematopoietic and nonhematopoietic stem cells and that conditions exist that can coax hematopoietic cells to express neural characteristics. In our laboratory, these cells were tested for several models of neurodegenerative diseases and spinal cord injuries. Through a series of transplantation studies we have begun to uncover the properties of HUCB‐derived cells in neuropoietic regions of the neonatal (1) and aging rodent brain. The systematic application of phenotyping approaches to characterize survival, migratory potential and morphologic properties of the differentiated HUCB progeny within normal/unaffected brain will serve as a base for understanding the potential effect of these cells in the diseased brain. Acknowledgements: Supported in part by R01 6155039 (TZ). HUCB cells were obtained from Saneron CCEL Therapeutics, Inc. and BioWhittaker, Inc.
A novel measurement strategy for volcanic ash fallout estimation based on RTD Fluxgate magnetometers (2008)

An innovative solution to measure the fallout of ETNA erupted volcano particles based on Residence Times Difference fluxgate magnetometer is here presented. The approach adopted is based on the exploitation of intrinsic magnetic properties of the emitted particles using a FR4 (flame resistant 4) fluxgate structure embedding a high permeability magnetic layer (Metglasreg ribbon, 1.6 mm thick) between two standard metallized layers. The proposed measurement system, for volcanic ash fallout estimation, represents an innovative direct sensing methodology, different from other current approaches that generally estimate the material in suspension and evaluate the expected fallout by using numerical models, such as satellite imaging, radar observations, Geostationary Operational Environmental Satellite, Moderate Resolution Imaging Spectroradiometer and the Atmospheric Infrared Sounder. The experimental set-up is here described and some preliminary results are reported to show the suitability of the approach proposed.
Early demonstration of a high VSWR microwave coaxial programmable impedance tuner with coaxial slugs (2015)

This paper reports a high voltage standing wave ratio (VSWR) impedance tuner with two independent slugs, which slide along a low-loss coaxial line. Impedance tuner are instruments used for characterizing performances of active microwave components and systems, and more particularly for load-pull and source-pull measurement of transistors, power or low noise amplifiers. After presenting the proposed tuner principle, a demonstrator based on a 3.5 mm coaxial line and designed to operate at microwave frequencies from 2 to 18 GHz is introduced. Then, its performances are measured and compared to simulation results. Finally, overall performances are compared to other currently commercialized impedance tuner technologies. Depending on the targeted frequency band, different slugs can be used to obtain an optimal VSWR. Slugs typically offers a 200∶1 VSWR. Their dimensions can be optimized in order to achieve very high VSWR in excess of 300∶1. The demonstrated tuner is very compact and achieve a minimum repeatability of −40 dB.
Understanding the structural and functional differences between mouse thyrotropin‐releasing hormone receptors 1 and 2 (2007)

Multiple computational methods have been employed in a comparative study of thyrotropin-releasing hormone receptors 1 and 2 (TRH-R1 and TRH-R2) to explore the structural bases for the different functional properties of these G protein-coupled receptors. Three-dimensional models of both murine TRH receptors have been built and optimized by means of homology modeling based on the crystal structure of bovine rhodopsin, molecular dynamics simulations, and energy minimizations in a membrane-aqueous environment. The comparison between the two models showed a correlation between the higher flexibility and higher basal activity of TRH-R2 versus the lesser flexibility and lower basal activity of TRH-R1 and supported the involvement of the highly conserved W6.48 in the signaling process. A correlation between the level of basal activity and conformational changes of TM5 was detected also. Comparison between models of the wild type receptors and their W6.48A mutants, which have reversed basal activities compared with their respective wild types, further supported these correlations. A flexible molecular docking procedure revealed that TRH establishes a direct interaction with W6.48 in TRH-R2 but not in TRH-R1. We designed and performed new mutagenesis experiments that strongly supported these observations.
RadioWeaves for efficient connectivity: analysis andimpact of\n constraints in actual deployments (2020)

We present a new type of wireless access infras-tructure consisting of a\nfabric of dispersed electronic circuitsand antennas that collectively function\nas a massive, distributed antenna array. We have chosen to name this new\nwireless infrastructure 'RadioWeaves' and anticipate they can be integrated\ninto indoor and outdoor walls, furniture, and otherobjects, rendering them a\nnatural part of the environment. Technologically, RadioWeaves will deploy\ndistributed arrays to create both favorable propagation and antenna array\ninteraction. The technology leverages on the ideas of large-scale intelligent\nsurfaces and cell-free wireless access. Offering close to the service\nconnectivity and computing, new grades in energy efficiency,reliability, and\nlow latency can be reached. The new concept moreover can be scaled up easily to\noffer a very high capacity inspecific areas demanding so. In this paper we\nanticipate how two different demanding use cases can be served well by a\ndedicated RadioWeaves deployment: a crowd scenario and a highly reflective\nfactory environment. A practical approach towards a RadioWeaves prototype,\nintegrating dispersed electronics invisibly in a room environment, is\nintroduced. We outline diverse R\\&amp;D challenges that need to be addressed to\nrealize the great potential of the RadioWeaves technology.\n
Phase Correlation Processing for DPIV Measurements: Part II — Spectral Domain Analysis (2007)

A novel Digital Particle Image Velocimetry (DPIV) correlation method is introduced which estimates the displacement using the phase content within the Fourier based cross-correlation. The use of weighted least squares and robust least squares estimation is introduced in order to improve the linear phase estimation of this technique. Spectral filters are constructed using the energy content of PIV images to define weighting functions for the dominant singular vector regressions. This performance of this technique is measured using Monte Carlo simulations of DPIV images. The resulting error analysis demonstrates substantially reduced errors for higher particle-image diameters for images containing low amounts of noise. For high noise images, the reduction in bias and RMS errors is not as drastic due to limitations of extracting the phase information. However, this correlation technique is able to eliminate peak-locking errors, shown to be a substantial source of error in noisy images, by directly extracting the displacement information in the spectral domain.
Double coincide rings-patterned plasmonic photonic crystal with engineered spectral emissivity for integrated thermal emitters (2022)

In this work we reported a photonic thermal light emitter based on double coincide rings-patterned photonic crystal structure of highly-doped silicon coated with platinum. The structure periodicity is 2 &mu;m and the rest of design dimensions were tuned to achieve either a wideband or multi-band wavelength range in the near and mid-infrared spectral ranges. Finite difference time domain analysis showed that a wide spectral range with a 3-dB spectral width of 3.7 &mu;m around 2.5 &mu;m central wavelength or dual-band operation with 3-dB spectral widths of 2.5 &mu;m and 3 around 1.5 and 7 &mu;m central wavelengths, respectively could be achieved.
On Multiflows in Random Unit-Disk Graphs, and the Capacity of Some Wireless Networks (2005)

We consider the capacity problem for wireless networks. Networks are modeled as random unit-disk graphs, and the capacity problem is formulated as one of finding the maximum value of a multicommodity flow. In this paper, we develop a proof technique based on which we are able to obtain a tight characterization of the solution to the linear program associated with the multiflow problem, to within constants independent of network size. We also use this proof method to analyze network capacity for a variety of transmitter/receiver architectures, for which we obtain some conclusive results. These results contain as a special case (and strengthen) those of Gupta and Kumar for random networks, for which a new derivation is provided using only elementary counting and discrete probability tools.
A 30-GHz class-F23 oscillator in 28nm CMOS using harmonic extraction and achieving 120 kHz 1/f3 corner (2017)

This paper presents a mmW frequency generation stage aimed at minimizing phase noise via waveform shaping and harmonic extraction while suppressing flicker noise upconversion via proper harmonic terminations. A second-harmonic tank resonance is assisted by a proposed embedded decoupling capacitor inside a transformer for shortest and well controlled common-mode current return path. Class-F operation with third-harmonic boosting and extraction techniques allow maintaining high quality factor of a 10 GHz tank at the 30 GHz frequency generation while providing implicit divide-by-3 functionality. The proposed 27.3-31.2 GHz oscillator is implemented in 28-nm CMOS. It achieves phase noise of -106 dBc/Hz at 1-MHz offset and figure-of-merit (FoM) of -184 dB at 27.3GHz. Its flicker phase-noise (1/f <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sup> ) corner of 120 kHz is an order-of-magnitude better than currently achievable at mmW.
13 DNA Topoisomerase Modification (1990)

I. INTRODUCTION The first reports of topoisomerase modification were published in 1982 and 1983 (Mills et al. 1982; Durban et al. 1983; Ferro et al. 1983; Jongstra-Bilen et al. 1983). Although a wide variety of posttranslational modifications of DNA topoisomerases may occur, this chapter focuses only on phosphorylation and poly(ADP-ribosylation), which have been observed both in vitro and in vivo. The experimental data suggest a regulatory role, but the precise cellular functions of these DNA topoisomerase modifications remain undefined at the present time. A. Phosphorylation of DNA Topoisomerase at Serine Residues The initial reports of phosphorylation in topoisomerases involved topoisomerase I purified from Novikoff hepatoma cells. A phosphoprotein of approximately 110 kD with a pI of 8.4 purified from cells labeled with 32 P (Durban et al. 1981) was subsequently identified as DNA topoisomerase I (Durban et al. 1983). A form of topoisomerase I could also be labeled in vitro by incubation with serine-specific protein kinases and [ 32 P]ATP. A protein kinase from an African Burkitt’s lymphoma cell line that appeared to exhibit high affinity for topoisomerase I was purified (Mills et al. 1982). This serine kinase had an apparent K m of approximately 0.3 μM for topoisomerase I; phosphorylation stimulated the DNA-relaxing activity of the enzyme three- to fivefold. The discovery of phosphorylation of topoisomerase I was followed by reports of phosphorylation of topoisomerase II. Sander et al. (1984) found a protein kinase activity that remained associated with Drosophila topoisomerase II through four purification steps. Phosphoserine was the predominant species modified by...
Spinning objects on horizontal planes (1983)

We present a simple theoretical analysis, of a common form of motion of a rotationally symmetric object (or symmetric top). The object, with its center of mass stationary, spins about its symmetry axis and rolls without slipping on a horizontal surface. The motion, which is referred to in the paper as ‘‘wobbling,’’ is long-lasting and stable and is exhibited by common objects (coins, bottles, plates, etc.) when they are spun on horizontal, flat surfaces. An apparatus is described for maintaining the ‘‘wobbling’’ motion of a metal cylinder, which can be observed in slow motion by means of stroboscopic illumination.
Mapping quantitative trait loci in inbred backcross lines ofLycopersicon pimpinellifolium(LA1589) (2002)

Although tomato has been the subject of extensive quantitative trait loci (QTLs) mapping experiments, most of this work has been conducted on transient populations (e.g., F2 or backcross) and few homozygous, permanent mapping populations are available. To help remedy this situation, we have developed a set of inbred backcross lines (IBLs) from the interspecific cross between Lycopersicon esculentum cv. E6203 and L. pimpinellifolium (LA1589). A total of 170 BC2F1 plants were selfed for five generations to create a set of homozygous BC2F6 lines by single-seed descent. These lines were then genotyped for 127 marker loci covering the entire tomato genome. These IBLs were evaluated for 22 quantitative traits. In all, 71 significant QTLs were identified, 15% (11/71) of which mapped to the same chromosomal positions as QTLs identified in earlier studies using the same cross. For 48% (34/71) of the detected QTLs, the wild allele was associated with improved agronomic performance. A number of new QTLs were identified including several of significant agronomic importance for tomato production: fruit shape, firmness, fruit color, scar size, seed and flower number, leaf curliness, plant growth, fertility, and flowering time. To improve the utility of the IBL population, a subset of 100 lines giving the most uniform genome coverage and map resolution was selected using a randomized greedy algorithm as implemented in the software package MapPop (http://www.bio.unc.edu/faculty/vision/lab/ mappop/). The map, phenotypic data, and seeds for the IBL population are publicly available (http://soldb.cit.cornell.edu) and will provide tomato geneticists and breeders with a genetic resource for mapping, gene discovery, and breeding.
Lymphokine secretion and cytotoxic activity of human CD4+ T-cell clones against Bordetella pertussis (1991)

Human CD4+ T-cell clones specific for pertussis toxin and other Bordetella pertussis antigens have been tested for their cytotoxic activity, lymphokine production, and capacity to induce immunoglobulin synthesis. Clones specific for the S1 subunit of pertussis toxin were cytotoxic for autologous Epstein-Barr virus-transformed B cells, which had been pulsed with the native antigen, the recombinant S1 subunit of pertussis toxin, or synthetic peptides derived from the S1 amino acid sequence. The killing of antigen-pulsed target cells was class II restricted. All of the T-cell clones produced mostly interleukin-2 and gamma interferon and assisted allogeneic B cells in the production of immunoglobulins M and G but not immunoglobulin E. The potential in vivo role of the cytotoxic activity of these clones is discussed.
Validation of the NAFLD Fibrosis Score in a Chinese Population With Low Prevalence of Advanced Fibrosis (2008)

The NAFLD fibrosis score has high negative predictive value in excluding advanced fibrosis in the Chinese population, and can reduce the burden of liver biopsy in the vast majority of cases. Since there were few cases of advanced fibrosis in this cohort, this study had limited power in validating the high cutoff point.
Deconvolution Analysis of FMRI Time Series Data (2006)

Program 3dDeconvolve was developed to provide deconvolution analysis of FMRI time series data. This has two primary applications: (1) estimation of the system impulse response function, and (2) multiple linear regression analysis of time series data. Given the input stimulus function(s), and the measured FMRI signal data, program 3dDeconvolve …rst estimates the impulse response function(s); the impulse response function(s) is then convolved with the stimulus time series to yield the estimated response. Various statistics are calculated to indicate the goodnessof the …t. The capability of …tting multiple stimulus (or reference) waveforms dierenti- ates program 3dDeconvolve from the cross-correlation analysis programs (such as AFNI …m and 3d…m). Another way that program 3dDeconvolve diers from the cross-correlation analysis programs is in the model for the output waveform. The cross-correlation programs model the system response as a scaled version of a …xed waveform (such as a square wave or a sine wave). Program 3dDeconvolve uses a sum of scaled and time-delayed versions of the stimulus time series. The data itself de- termines (within limits) the functional form of the estimated response. In fact, the shape of the …tted waveform can vary from voxel to voxel. Program 3dDeconvolve is described in Section 1. Since program 3dDeconvolve was developed for use in a batchprocessing mode, it should be used in conjunction with the interactive program plug_deconvolve. See the documentation for program plug_deconvolve for a description of this interactive version. The details are contained in Section 2. Program RSFgen is a simple program for generating random stimulus functions. This capability may be useful for experimental design, and the evaluation of experi- mental designs. This program is described in Section 3. Program 3dConvolve, as the name implies, performs the inverse operation of pro- gram 3dDeconvolve. That is, program 3dConvolve convolves the input stimulus func- tions with the given system impulse response functions, in order to predict the output measured response. This program is described in Section 4.
Exploration of Full HD Media Decoding on a Software Defined Radio Baseband Processor (2013)

Recently, various specialized Software Defined Radio (SDR) baseband processors have been proposed for meeting the high performance and programmability requirements for emerging wireless communication applications. In order to support high throughput wireless communication, the SDR baseband processors typically employ many parallel computation elements, which may also be used for performing other signal processing applications. This paper explores the feasibility of performing complex media processing on such SDR baseband processors. Specifically, the full HD 1080p state-of-the-art H.264/AVC media decoding has been implemented onto a recent version of the ADRES based SDR baseband processor. Since the processor was originally designed exclusively for wireless baseband applications, algorithm and architecture co-optimizations are required to make the goal feasible. Following algorithm analysis, the computationally dominant tasks of the H.264/AVC, including the motion compensation, the intra prediction, the inverse integer transform, and the deblocking filter, have been selected to be mapped onto the ADRES. The experimental results show that, with limited architectural extensions, the ADRES based baseband processor achieves competitive performance efficiency, even compared with several processors that are specifically optimized for the media decoding application.
Flaxseed Supplementation (Not Dietary Fat Restriction) Reduces Prostate Cancer Proliferation Rates in Men Presurgery (2008)

Findings suggest that flaxseed is safe and associated with biological alterations that may be protective for prostate cancer. Data also further support low-fat diets to manage serum cholesterol.
Use of Abnobaviscum to treat refractory seroma after breast reconstruction with a latissimus dorsi flap: A case report (2019)

In recent years, there has been a notable increase in the rate of refractory donor site seroma, defined as seroma that persists for at least 3 months postoperatively, as the number of breast reconstructions using a latissimus dorsi (LD) musculocutaneous flap has increased. Various factors have been proposed to be related, including smoking, obesity, flap mass, and body weight, and several studies have been conducted to explore treatment methods. Typically, surgical treatment, such as capsulectomy, has been considered for refractory seroma, but in this case report, we describe positive outcomes achieved by using Abnobaviscum to treat three female patients who developed a donor site seroma at least 3 months after breast reconstruction using an LD flap.
Distribution circuit state estimation using a probabilistic approach (1997)

Past work on distribution circuit state estimation has focused on the adoption of a transmission state estimator approach, without necessarily accounting for the specific requirement of a distribution circuit-based analysis. On distribution circuits, typically, there are very few available real-time measurements, and thus, researchers have treated customer load demand estimates as pseudo-measurements in a weighted-least-squares formulation. This can lead to convergence problems and also, the approach effectively assumes that all bus load demands are normally distributed (Gaussian) which may not be valid on distribution circuits. This paper presents an alternative approach to distribution circuit state estimation using a probabilistic extension of the radial load flow algorithm while accounting for real-time measurements as solution constraint. The algorithm which takes advantage of the radial nature of distribution circuits also accounts for other issues specific to distribution circuits. Namely, the algorithm accounts for nonnormally distributed loads, incorporates the concept of load diversity (load correlation) and can interact with a load allocation routine. The effectiveness of the algorithm is illustrated through comparisons made with Monte Carlo simulations.
Comparison of Double Star Topologies of Modular Multilevel Converters in STATCOM Application (2018)

The modular multilevel converters (MMCs) have shown great emphasis in academic studies of the last decades, specially applied in renewable energy systems, HVDC systems, energy storage, electrical drives and STATCOMs. In STATCOM applications, in particular, the Double Star (DS) configuration has several operating advantages, mainly related to its ability to compensate negative sequence components and unbalanced currents. Considering the advantage of these topologies in STATCOM application, it is proposed in this work a comparison of two DS topologies: Double Star Chopper-Cell (DSCC) and Double Star Bridge-Cell (DSBC). These topologies are compared in terms of steady-state operation, power losses and costs. In addition, two variations of DSBC topology are approached: DSBC-2L, which employs 2-level modulation and DSBC-3L, which employs 3-level modulation. The three MMC topologies are designed based on a 15 MVA STATCOM connected in a 13.8 kV grid. The simulation results validate the design methodology and also indicates the DSBC-3L topology as a promising solution for medium voltage STATCOMs due to its costs, protection during short circuits and smaller insulation requirements.
At Tape-out: Can System Yield in Terms of Timing/Energy Specifications Be Predicted? (2007)

Process variability is introducing uncertainty in all the system level parametric specifications. Existing variability aware techniques can only capture and model the variations on system timing and leakage power. This paper proposes a framework that can capture variability in the dynamic energy consumption as well. It percolates variability information from semiconductor process to the Register Transfer Level. This enables to capture the application dynamics and provide an accurate estimation of dynamic energy along with leakage and timing.