gebhart/patrepeval huggingface dataset:
Excitation energies in trimethylenemethane derivatives (1982)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTExcitation energies in trimethylenemethane derivativesSheila B. Auster, Russell M. Pitzer, and Matthew S. PlatzCite this: J. Am. Chem. Soc. 1982, 104, 14, 3812–3815Publication Date (Print):July 1, 1982Publication History Published online1 May 2002Published inissue 1 July 1982https://pubs.acs.org/doi/10.1021/ja00378a006https://doi.org/10.1021/ja00378a006research-articleACS PublicationsRequest reuse permissionsArticle Views51Altmetric-Citations30LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Plasma generation by dielectric resonator arrays (2016)

Arrays of dielectric resonators—illuminated by an antenna—are used to ignite and sustain multiple microwave plasmas in parallel. Calcium titanate cylindrical resonators were arranged in a linear array with separation distances between 0.5 and 5 mm. The operating frequency was near the HEM111 resonance of 1.1 GHz. Paschen curves of the breakdown field and voltage in argon atmosphere are consistent with parallel plate microwave breakdown except within discharge gaps of 1 mm or less. Sustaining of argon plasma between 0.5 Torr and 1 atm within the array is found to alter the electromagnetic scattering from the dielectric resonators, suggesting applications in plasma-reconfigurable metamaterials and photonic crystals.
<title>Multicarrier business customer premises network</title> (1995)

A concept for a business customer premises network using both coherent multi-channel transmission and ATM is presented. It is shown that a flexible, upgradable high capacity network can be realized, well-suited for the provision of distributive, retrieval, and interactive broadband services. Based on this concept a complete demonstrator is being realized, addressing all broadband communication aspects like network control, wavelength management, network security, field installation, broadband signaling etc.
Experimental and Modelling Investigation of Re-Adhesion Mechanism of Detached Nanoparticles to Wafer Surface in Spin Rinse Process (2020)

Adhesive particles on polished wafers are detached by e.g. scrubbing, and removed by liquid flow from the wafer. However, the relationship between the characteristic of liquid flow and the removal of detached particles has not yet been examined in detail. Therefore, the re-adhesion of detached particles to wafer surfaces in liquid flow on rotating wafers was experimentally investigated. The number of residue particles on a wafer was counted using a defect inspection tool after de-ionized water (DIW) rinse for particle removal. To discuss the mechanism of particle removal, a model was constructed and compared with experimental results. The model is based on boundary layer theory of fluid dynamics and advection diffusion theory of transport phenomena for particle removal in liquid flow near the wafer surface. The model results confirmed that detached particles in liquid flow moved into the sublayer and re-adhered to the wafer surface by diffusion. Moreover, particles in the sublayer, where the liquid velocity is several hundred um/s, could not be moved from the sublayer and removed from the wafer. It was also found that the number of particles re-adhering to the wafer surface depends on the Sherwood number.
Focused Ion Beam as a Nanofabrication Tool for Rapid Prototyping of Nanomagnetic Devices (2006)

Extended abstract of a paper presented at Microscopy and Microanalysis 2006 in Chicago, Illinois, USA, July 30 – August 3, 2005
Selective cyclohexene oxidation with O2, H2O2 and tert-butyl hydroperoxide over spray-flame synthesized LaCo1−xFexO3 nanoparticles (2020)

A series of spray-flame made LaCo<sub>1−x</sub>Fe<sub>x</sub>O<sub>3</sub> nanoparticles showed promising activity for liquid-phase cyclohexene oxidation. Various oxidizing agents, <italic>i.e.</italic>, O<sub>2</sub>, H<sub>2</sub>O<sub>2</sub> and <italic>tert</italic>-butyl hydroperoxide, led to different product selectivities.
Synthesis of α‐Carboline (2017)

Abstract The article reports synthesis of α‐Carboline. This heterocycle has found utility as a building block in natural product and medicinal chemistry as well as in optoelectronic materials. Literature procedures for the preparation of 2 fall into two general catagories: thermolysis of a pyridylbenzotriazole, with extrusion of nitrogen leading to bond formation (a modified Graebe‐Ullman reaction) or formation of the C4a‐C4b bond from an aryl halide–aryl‐H intramolecular coupling.
Surface characterization of electrically conducting nickel tetrathiooxalate/poly(vinyl alcohol) composites (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSurface characterization of electrically conducting nickel tetrathiooxalate/poly(vinyl alcohol) compositesW. F. Stickle, J. R. Reynolds, and C. A. JollyCite this: Langmuir 1991, 7, 11, 2460–2463Publication Date (Print):November 1, 1991Publication History Published online1 May 2002Published inissue 1 November 1991https://pubs.acs.org/doi/10.1021/la00059a011https://doi.org/10.1021/la00059a011research-articleACS PublicationsRequest reuse permissionsArticle Views126Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Determination of the Absolute Rate Constants in Free-Radical Polymerization of Zwitterionic Sulfobetaine Monomers (1993)

Abstract The absolute rate constants in the free-radical polymerization of zwitterionic sulfobetaine monomers [3-dimethyl(methacryloyloxyethyl) ammonium propane sulfonate (DMAPS) and 3-dimethyl(acryloyloxyethyl) ammonium propane sulfonate (DAAPS)] were investigated in formamide/dioxane cosolvent at 30°C. The rate of initiation (Rp 2) and Kp 2/kt were determined using DPPH as the inhibitor. The propagation rate constant (kp ) and termination rate constant (kt ) were determined by intermittent illumination methods. The kp values of DMAPS in the presence and absence of NaCl were determined to be 2760 and 1470 (L · mol−1·- s−1), respectively. The enhanced polymerization rate of DMAPS in the presence of NaCl can be ascribed to the large kp value, which may be due to the less electrostatic repulsive force and/or to the greater solubility in NaCl of the growing chain. The kp of DMAPS was 50% lower than that of DAAPS, both in the presence and absence of NaCl, indicating that steric hindrance in the α-carbon position of DMAPS is important during polymerization. The termination rate constant is not significantly affected by the presence of NaCl.
Tumor-specific recombinant idiotype immunisation after chemotherapy as initial treatment for follicular non-Hodgkin lymphoma (2009)

Tumor-specific variable regions of the clonal immunoglobulin (idiotype, Id) expressed by B cell non-Hodgkin lymphoma (NHL) can be targeted by active immunotherapy. We conducted a phase I/II trial to determine the safety and immunogenicity of a patient-specific, recombinant, mammalian cell-derived Id protein conjugated to keyhole limpet hemocyanin (Id-KLH; MyVax personalised immunotherapy) in 22 patients with follicular NHL in first remission after chemotherapy. Subjects received five subcutaneous immunisations with MyVax plus locally administered granulocyte-macrophage colony-stimulating factor (GM-CSF). Among 21 evaluable patients, 62% mounted Id-specific immune responses. Evoked anti-Id antibodies recognised both recombinant Id and native Id, and could specifically stain autologous tumor cells. At median follow-up of more than 6 years, median progression-free survival is 38 months. Immunisation of follicular lymphoma patients with MyVax Id-KLH is safe and patients often mount tumor-specific immune responses. These results form the basis of a pivotal phase 3 trial of MyVax in follicular NHL.
The Effect of Triple Pelvic Osteotomy on the Articular Contact Area of the Hip Joint in Dysplastic Dogs: An in Vitro Experimental Study (1998)

This study suggests that increasing AVV beyond 20 degrees does not significantly improve the beneficial effects of TPO and therefore should be carefully weighed against increased risks of postoperative complications associated with large angles of AVV.
Supplementary Data from Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages (2023)

Supplementary Data from Efficacy of CD40 Agonists Is Mediated by Distinct cDC Subsets and Subverted by Suppressive Macrophages
Evaluation of a Feature Compensation Approach Using High-Order Vector Taylor Series Approximation of an Explicit Distortion Modelon Aurora2, Aurora3, and Aurora4 Tasks (2008)

In our previous work, a new feature compensation approach to robust speech recognition was proposed by using high-order vector Taylor series (HOVTS) approximation of an explicit model of distortions caused by additive noises, and evaluation results were reported on Aurora2 database. This paper extends the above approach to deal with both additive noises and convolutional distortions, and reports evaluation results on Aurora2, Aurora3, and Aurora4 tasks.
Is it Necessary to Remove the Seminal Vesicles Completely at Radical Prostatectomy? Decision Curve Analysis of European Society of Urologic Oncology Criteria (2008)

Whether to use the European Society of Urological Oncology algorithm depends not only on its accuracy, but also on the relative clinical consequences of false-positive and false-negative results. Our threshold of 75 is an intermediate value that is difficult to interpret, given uncertainties about the benefit of seminal vesicle sparing and harm associated with untreated seminal vesicle invasion. We recommend more formal decision analysis to determine the clinical value of the European Society of Urological Oncology algorithm.
Convenient Entry to α‐Amino‐β‐hydroxy‐γ‐methyl Carboxylic Acids. Diastereoselective Formation and Directed Homogeneous Hydrogenation of 3‐(3‐Aryl‐1‐hydroxy‐2‐methylprop‐2‐enyl)‐1,4‐benzodiazepin‐2‐ones (2003)

Abstract Aldol reaction of 7‐chloro‐1,3‐dihydro‐1‐methyl‐5‐phenyl‐2 H ‐1,4‐benzodiazepin‐2‐one ( 1 ) with 4‐substituted α ‐methylcinnamaldehydes 2 – 5 afforded a mixture of threo ‐ and erythro ‐3‐(3‐aryl‐1‐hydroxy‐2‐methylprop‐2‐enyl)‐7‐chloro‐1,3‐dihydro‐1‐methyl‐5‐phenyl‐2 H ‐1,4‐benzodiazepin‐2‐ones 6 – 13 . The chromatographically separated threo diastereoisomers 6, 8, 10 , and 12 and erythro diastereoisomers 7, 9, 11 , and 13 were submitted to ‘directed' homogeneous hydrogenation catalyzed by [Rh I (cod)(diphos‐4)]ClO 4 (cod=cycloocta‐1,5‐diene, diphos‐4=butane‐1,4‐diylbis[diphenylphosphine]. From the erythro ‐racemates 9, 11 , and 13 , the erythro,erythro / erythro,threo ‐diastereoisomer mixtures 16 / 17, 20 / 21 , and 24 / 25 were obtained in ratios of 20 : 80 to 28 : 72 (HPLC), which were separated by chromatography. From the threo racemates 8, 10 , and 12 , the threo,threo / threo,erythro ‐diastereoisomer mixtures were obtained in a ratio of ca. 25 : 75 ( 1 H‐NMR). The relative configurations were assigned by means of 1 H‐NMR data and X‐ray crystal‐structure determination of 21 . Hydrolysis of 21 afforded the diastereoisomerically pure N ‐(benzyloxy)carbonyl derivative 27 of α ‐amino‐ β ‐hydroxy‐ γ ‐methylpentanoic acid 26 , representative of the novel group of polysubstituted α ‐amino‐ β ‐hydroxycarboxylic acids.
Membrane Engineering: Phase Separation in Polymeric Giant Vesicles (2020)

Cell membranes exhibit elaborate lipidic patterning to carry out a myriad of functions such as signaling and trafficking. Domain formation in giant unilamellar vesicles (GUVs) is thus of interest for understanding fundamental biological processes and to provide new prospects for biocompatible soft materials. Lipid rearrangements in lipidic GUVs and lipid/polymer GUVs are extensively studied whereas polymer/polymer hybrid GUVs remain evasive. Here, the focus is on the thermodynamically driven phase separation of amphiphilic polymers in GUVs. It is demonstrated that polymer phase separation is entropically dictated by hydrophobic block incompatibilities and that films topology can help to determine the outcome of polymeric phase separation in GUVs. Lastly, Janus-GUVs are obtained and GUVs exhibit a single large domain by using a compatibilizing hydrophobic block copolymer.
Bacterial and parasitic factors diagnosed in eel farmed in Poland in the years 2010-2014 (2016)

European eel Anguilla anguilla L. is a fish species highly valued in European fisheries, currently reared under controlled conditions (Aquatic Recirculation System - RAS). In order to protect the health of fish, regular check-ups are carried out in specialized veterinary laboratories. Health hazards are recognized on the basis of clinical, pathological, microbiological, and parasitological surveys. The aim of the study was to analyze the results of health assessment of eels reared under controlled conditions, which was performed in the Diagnostics Laboratory of Fish and Crayfish Diseases, Department of Veterinary Hygiene, Voivodeship Veterinary Inspectorate in Olsztyn, in the period from 2010 to 2014. The results are presented according to the etiologic agents, divided into bacterial and parasitic diseases. In this period, 73 samples (100%) were examined, including 5 samples (6.85%) from glass eels and 68 (93.15%) from elvers. Microorganisms isolated from the collected material were mainly conditionally pathogenic, such as Pseudomonas fluorescens, Aeromonas hydrophila, Shewanella putrefaciens, Aeromonas sobria, Flavobacterium spp., and Chryseobacterium indologenes. The parasitological examination revealed infection with Trichodina spp., Ichthyophtirius multiphilliis, and Pseudodactylogyrus spp. The most frequently diagnosed were gill monogeneans, detected in 34 cases (75.55% of all positive parasitological test results). In 21 cases (61.8%) the infestation manifested itself as a disease. The remaining 13 cases were asymptomatic carriers (38.2%). The analysis shows that the main problem in the controlled rearing of eel are parasitic infestations, which may be endemic and pose a constant threat. Systematic monitoring and preventive measures are necessary throughout the rearing and fattening of fry to maintain a good health status of eels.
Weakly-supervised Discriminative Patch Learning via CNN for Fine-grained Recognition. (2016)

Compared to earlier multistage frameworks using CNN features, recent end-to-end deep approaches for fine-grained recognition essentially enhance the mid-level learning capability of CNNs. Previous approaches achieve this by introducing an auxiliary network to infuse localization information into the main classification network, or a sophisticated feature encoding method to capture higher order feature statistics. We show that mid-level representation learning can be enhanced within the CNN framework, by learning a bank of convolutional filters that capture class-specific discriminative patches without extra part or bounding box annotations. Such a filter bank is well structured, properly initialized and discriminatively learned through a novel asymmetric multi-stream architecture with convolutional filter supervision and a non-random layer initialization. Experimental results show that our approach achieves state-of-the-art on three publicly available fine-grained recognition datasets (CUB-200-2011, Stanford Cars and FGVC-Aircraft). Ablation studies and visualizations are provided to understand our approach.
Canakinumab as treatment for COVID-19-related pneumonia: A prospective case-control study (2020)

Treatment with canakinumab in patients with COVID-19-related pneumonia rapidly restored normal oxygen status, decreased the need for invasive mechanical ventilation, and was associated with earlier hospital discharge and favourable prognosis versus standard of care.
Allergen‐specific immunotherapy with a monophosphoryl lipid A‐adjuvanted vaccine: reduced seasonally boosted immunoglobulin E production and inhibition of basophil histamine release by therapy‐induced blocking antibodies (2003)

Successful immunotherapy with the MPL-adjuvanted grass pollen allergy vaccine is associated with the production of allergen-specific IgG antibodies. These blocking antibodies may have protective effects by inhibiting immediate-type reactions and systemic increases of IgE responses caused by seasonal allergen exposure.
Determination of nematic polar anchoring from retardation versus voltage measurements (1999)

The popular “high-electric-field” technique to determine the polar anchoring coefficient W of a nematic–substrate interface requires the simultaneous measurement of the capacitance and optical phase retardation of a liquid crystal cell as a function of applied voltage. We develop a generalized model that makes it possible to eliminate the capacitance measurement. The new technique, called the RV (retardation versus voltage) technique, requires only the measurement of retardation as a function of applied voltage, and allows for the determination of W by a linear fit over a prescribed voltage window. The technique is not sensitive to uniformity of the cell thickness, does not require patterned electrodes, and allows for the local probe of the surface. The value of W obtained by the RV technique is the same as W obtained by the traditional technique.
Comparison of Proximal Porous-Coated and Grit-Blasted Surfaces of Hydroxyapatite-Coated Stems (2004)

Therapeutic study, Level II-1 (prospective cohort study). See Instructions to Authors for a complete description of levels of evidence.
Friction-curve peak detection by wheel-deceleration measurements (2006)

Tire-road friction characteristics are deeply interlaced with all vehicle safety oriented control systems, as road conditions strongly affect the control schemes behavior. In this work we focus on estimating the peak-value of the tire-road friction curve, as this is the stability boundary for the wheel braking dynamics. Moreover, we show how such algorithm can be employed as a supervisory control to enhance safety properties and performance of current anti-lock braking systems. The proposed strategy is analyzed and tested for different sensors' configurations, i.e., with and without longitudinal wheel slip measurement available and its validity is assessed on experimental data collected on a test vehicle
3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel (2019)

Bedaquiline is a new drug of the diarylquinoline class that has proven to be clinically effective against drug-resistant tuberculosis, but has a cardiac liability (prolongation of the QT interval) due to its potent inhibition of the cardiac potassium channel protein hERG. Bedaquiline is highly lipophilic and has an extremely long terminal half-life, so has the potential for more-than-desired accumulation in tissues during the relatively long treatment durations required to cure TB. The present work is part of a program that seeks to identify a diarylquinoline that is as potent as bedaquiline against Mycobacterium tuberculosis, with lower lipophilicity, higher clearance, and lower risk for QT prolongation. Previous work led to the identification of compounds with greatly-reduced lipophilicity compounds that retain good anti-tubercular activity in vitro and in mouse models of TB, but has not addressed the hERG blockade. We now present compounds where the C-unit naphthalene is replaced by a 3,5-dialkoxy-4-pyridyl, demonstrate more potent in vitro and in vivo anti-tubercular activity, with greatly attenuated hERG blockade. Two examples of this series are in preclinical development.
A statin‐based inhibitor of lymphocyte function antigen‐1 protects against ischemia/reperfusion‐induced leukocyte adhesion in the colon (2003)

1. Statins are mainly used to control hypercholesterolemia; however, recent studies have also ascribed anti-inflammatory effects to the statins. LFA703 is a novel statin-derived compound, which potently inhibits lymphocyte function antigen-1 (LFA-1, CD11a/CD18) but does not affect HMG-CoA reductase activity. 2. The objective of this study was to examine the anti-inflammatory mechanisms of LFA703 in ischemia/reperfusion (I/R)-induced leukocyte-endothelium interactions in the colon. For this purpose, the superior mesenteric artery was occluded for 30 min and leukocyte responses were analyzed in colonic venules after 120 min of reperfusion in mice using inverted intravital fluorescence microscopy. 3. First, the inhibitory mechanisms of LFA703 on leukocyte adhesion were investigated in vitro using a mouse CD4+8+ thymocyte cell line. Immunoneutralization of LFA-1 and ICAM-1 abolished leukocyte adhesion, whereas inhibition of VLA-4 had no effect in this in vitro assay. Indeed, it was found that LFA703 dose-dependently reduced LFA-1-dependent leukocyte adhesion to mouse endothelial cells in vitro with an IC50 of 3.2 microm. 4. I/R caused an increase in leukocyte rolling and adhesion in colonic venules. Immunoneutralization of LFA-1 significantly reduced I/R-induced leukocyte adhesion by 89% in colonic venules. In contrast, I/R-provoked leukocyte rolling was insensitive to inhibition of LFA-1 function. 5. Administration of 30 mg kg-1 of LFA703 decreased reperfusion-induced leukocyte adhesion by more than 91%, while the level of leukocyte rolling was unchanged, suggesting that LFA703 effectively blocked LFA-1-dependent firm adhesion of leukocyte in the colon. However, LFA703 did not decrease the expression of LFA-1 on circulating leukocytes. 6. This study demonstrates that LFA-1 is indeed a critical adhesion molecule in mediating postischemic leukocyte adhesion in the colon. Moreover, this is the first study showing that a statin-based synthetic compound has the capacity to abolish LFA-1-dependent leukocyte adhesion in I/R. These novel findings may have great implications in the clinical treatment of conditions associated with I/R-induced tissue injury, such as organ transplantation, trauma and major surgery.