gebhart/patrepeval huggingface dataset:
Magnetic Resonance Imaging in Acute Spinal Cord Trauma (1988)

Magnetic resonance imaging (MRI) has proven to be an invaluable tool for evaluating neoplastic, congenital, and degenerative conditions of the spine and spinal cord. Because of various technical limitations, however, the use of MRI in acutely spinal cord-injured patients has not been fully explored. Sixty-two spinal cord-injured patients underwent MRI within the first 36 hours of injury. A variety of pathological findings were detected on the MRI scans: anatomical cord transection (7 cases), spinal cord deformity secondary to extrinsic compression (28), focal cord enlargement/swelling (21), hyperintense intramedullary lesions (17), and disc herniations (2). MRI may be a useful adjunct in the evaluation of acute spinal cord injury.
Supplementary Legend from MicroRNA Array Analysis Finds Elevated Serum miR-1290 Accurately Distinguishes Patients with Low-Stage Pancreatic Cancer from Healthy and Disease Controls (2023)

&lt;p&gt;Supplementary Legend - PDF file 87K Supplementary legend&lt;/p&gt;
Relaxation oscillator calibration technique with comparator delay regulation (2016)

This paper presents an improved technique for the calibration of the relaxation oscillators with respect to the delay of the comparators. The drawbacks of the conventional topology for the relaxation oscillators are analyzed. Based on the analysis, the circuit modification which resolves the effects of the comparator delay in the trimming procedure is proposed. The simulations in ams 0.18μ CMOS technology exhibit more than 5x the improvement in the precision compared to the conventional topology, evaluated in the temperature range from -40 to 125 °C.
Implantable Left Ventricular Assist Devices Provide an Excellent Outpatient Bridge to Transplantation and Recovery (1997)

Outpatient LVAD support is safe and provides improved quality of life for patients awaiting transplantation. Wearable and totally implantable LVADs should be studied as permanent treatment options for patients who are not candidates for heart transplantation.
Single Nucleotide Polymorphisms in the Proximal Promoter Region of the Adiponectin (APM1) Gene Are Associated With Type 2 Diabetes in Swedish Caucasians (2004)

Adiponectin (APM1) is an adipocyte-derived peptide. The APM1 gene is located on chromosome 3q27 and linked to type 2 diabetes. In patients with type 2 diabetes, the adiponectin level in plasma is decreased in comparison to healthy subjects. To identify genetic defects of the APM1 gene that contribute to the development of type 2 diabetes, we genotyped 13 single nucleotide polymorphisms (SNPs) in 106 patients with type 2 diabetes, 325 patients with impaired glucose tolerance (IGT), and 497 nondiabetic control subjects in Swedish Caucasians by using dynamic allele-specific hybridization (DASH). We found that SNPs -11426(A/G) and -11377(G/C) in the proximal promoter region had significant differences of allele frequencies between type 2 diabetic patients and nondiabetic control subjects (P = 0.02 and P = 0.04, respectively). SNP-11426(A/G) was significantly associated with fasting plasma glucose in type 2 diabetic patients (P = 0.02) and in IGT subjects (P = 0.04), while the patients carrying CC and CG genotypes for SNP-11377(G/C) had a higher BMI than the patients with the GG genotype (P = 0.03). Haplotype analysis of 13 SNPs in the APM1 gene showed that estimates of haplotype frequencies in Swedish Caucasians are similar to those estimated in French Caucasians. However, no significant association of haplotypes with type 2 diabetes and IGT was detected in our study. The present study provides additional evidence that SNPs in the proximal promoter region of the APM1 gene contribute to the development of type 2 diabetes.
Pyrazole trk kinase inhibitors for the treatment of cancer (2007)

Two related applications from AstraZeneca claim novel pyrazole derivatives and their process for preparation as trk kinase inhibitors for use in oncology. The compounds are claimed for stand-alone or combination therapy. The two series, which differ by position of attachment of the pyrazole group, are prepared from a common intermediate by reversing the order of the aminopyrazole step. TrkA kinase data are provided for three examples in each application.
CRLH ZOR ANTENNA OF A CIRCULAR MICROSTRIP PATCH CAPACITIVELY COUPLED TO A CIRCULAR SHORTED RING (2011)

In this paper, a novel Metamaterial (MTM) CRLH Zeroth Order Resonance (ZOR) Circular microstrip patch antenna is proposed to have a monopole antenna pattern due to the completely closed loop of a magnetic current around the structure, and reduced proflle and size due to the left-handedness. Difierent from other ZOR antennas of 1D periodic arrays with shorted patches, we suggest 1 circular patch capacitively coupled to 1 circular shorted ring to have ZOR and i1st resonance modes. The antenna is designed and modeled with equivalent circuits for the coaxial-fed central patch and the circular shorted ring and verifled by the comparison with 3D EM simulation of the physical structure. The no-phase variation at the ZOR (2.4GHz) and the i1st resonance mode (2GHz) as the metamaterial properties are proven with electric fleld distributions and far-fleld patterns. The measurement shows there exist the ZOR and the i1 resonance modes despite the frequency shift from the simulation, which is proven by the monopolar radiation pattern and broadside radiation pattern, respectively. So the advantages of the proposed antenna will be addressed with the low-proflle monopole at the ZOR and the size reduction efiect at the i1st resonance.
Session A (compound semiconductor devices) (2015)

Start of the above-titled section of the conference proceedings record.
Amorphous and Poorly Ordered Polymers (2011)

This chapter contains sections titled: Introduction Glassy Amorphous Polymers Rubbers Polymer Gels Interpenetrating Polymer Networks References
Complications of Psychotropic and Pain Medications in an Ultrarapid Metabolizer Patient at the Upper 1% of Cytochrome P450 (CYP450) Function Quantified by Combinatorial CYP450 Genotyping (2017)

A 44-year-old Caucasian woman presented with a history of empirical treatment with 20 pain and psychotropic medications, as well as dual comorbidity of intractable pain and depression. A multiple gain-of-function profile in the CYP450 family of cytochrome P450 (CYP450) drug metabolism isoenzymes was discovered. The patient was a homozygote of suprafunctional alleles for both CYP2D6 (<sup>*</sup>35/<sup>*</sup>35) and CYP2C19 (<sup>*</sup>17/<sup>*</sup>17) genes and functional alleles for CYP2C9 (<sup>*</sup>1/<sup>*</sup>1), which account for aggregate drug metabolism function at the upper 1% of the population. The patient improved clinically with discontinuation of psychotropics and pain medications that were substrates of CYP2D6 and/or CYP2C19, suggesting that much of her symptomatology was drug induced. Combinatorial genotyping of CYP450 genes is diagnostically useful in individuals with histories of multiple side effects or drug resistance, which could be avoided by genetically informed therapeutics in behavioral health.
Structural Intensity Modeling and Simulations for Damage Detection (2012)

Structural health monitoring (SHM) techniques have previously been proposed based on structural intensity (SI) due to its sensitivity to changes in boundary and loading conditions, and impedance, as well as to various damage mechanisms. In this paper, computational techniques for SI-based SHM are presented. Finite element solvers combined with SI equations can yield intensity maps over structures to determine characteristic changes in power flow due to damage. Numerical techniques for structural surface intensity (SSI) are also introduced using two alternative methods: A time domain approach that directly uses SSI equations that are valid at the surface of any elastic solid, and a frequency domain technique, which computes SI for very thin plate elements located at the surface of the structure. Advanced contact features such as nonlinearity can also be included in the model to increase the damage detection sensitivity. A plate model is used to illustrate these capabilities using SSI maps at nonlinear harmonics (NSSI). The results show both improved damage sensitivity and more global detection capabilities in a NSSI-based SHM system. A complex structure is also included to show global and local changes in SSI due simulated damage scenario. The techniques developed can be applied to general SI/SSI assessments and the design of SI-based SHM systems.
Spatiotemporal Clustering of Urban Networks (2015)

The problem of modeling traffic in urban areas is especially relevant because of the urgent need for managing congestion in big cities. In recent years, the macroscopic fundamental diagram (MFD) has been proposed as a macroscopic description of urban traffic. The MFD has been proved useful in the design of control strategies. However, the MFD cannot be properly defined if congestion across the city is heterogeneously distributed and if its characteristics change with time. This situation is common in large cities, and a method for identifying homogeneous areas in space and time is needed. This paper proposes a spatiotemporal clustering method with which to detect homogeneous areas over the network and over time. In each of these areas, an MFD can be defined. In particular, a segmentation method is proposed that can divide the time intervals into segments optimizing the clustering results within each of them. The algorithm is applied to data collected in the city of London, where a control system called SCOOT (split-cycle offset optimization technique) is in operation.
Polarization-insensitive single balanced photodiode coherent receiver for passive optical networks (2015)

Alamouti polarization-time block coding, combined with heterodyne detection, enables phase-diverse coherent detection using a single balanced photodiode without optical polarization tracking. A 10.7Gb/s OFDM signal is experimentally rotated over the full Poincare sphere achieving a mean receiver sensitivity of -35.8dBm.
Closing the Loop on Regulatory Authority vs. Institutional Autonomy in an Age of Accountability “The Government’s Role in Accreditation” (2008)

The guiding theme that has given impetus to the federal government’s continued involvement in issues of accreditation has been that the government has sought to increase its control of higher education through accreditation. As Pedersen (2005) surmises, “…the federal government has chosen to use theregional associations as a "Trojan horse" to exert greater influence onaccreditation.” However, if representatives of Department of Education areasked, they will claim that the department has been motivated by an honestdesire to ensure that the public is not misled by false claims of quality and valuemade by colleges and universities. On the contrary, most colleges anduniversities would disagree, claiming that the government has been simplyattempting to use accreditation to force higher education to adopt policies andpractices that advance a political ideology.
Surgery as an Effective Early Intervention for Diabesity (2005)

We are currently in the midst of two closely linked epidemics: type 2 diabetes and obesity (1,2). At the present time, it is estimated that 190 million people worldwide have diabetes and that this will increase to 324 million by 2025 (3). This epidemic is taking place in both developed and developing nations. In the U.S. alone, at least 16 million people have type 2 diabetes, with 1 million more diagnosed annually (4). Obesity is also increasing at alarming rates. In the U.S., the majority diagnosed with type 2 diabetes are overweight, with 50% obese (i.e., BMI >30 kg/m2) and 9% morbidly obese (BMI >40 kg/m2) (5).

There is a strong relationship between obesity and type 2 diabetes, and the term “diabesity” has been coined to suggest a single problem (6,7). A substantial portion of the health costs attributed to obesity is related to type 2 diabetes (8). The socioeconomic impact of type 2 diabetes and its complications are substantial to individuals and their families and to society (9). In particular, it is an inexorably progressive disease, leading to deterioration in multiple organs and systems, and is the most common cause of adult blindness, limb amputations, and renal failure in western communities, as well as the leading independent risk factor for coronary artery disease (10).

Prevention of this diabesity epidemic through effective public health lifestyle and environmental initiatives to change the population’s dietary and movement behaviors should be of highest priority (2). For those already suffering from diabesity, effective treatment is important. A therapy that provides remission of both diabetes and obesity should attract enormous interest and activity.

Theoretically, weight loss is such a therapy (11,12). However, although intentional weight loss through diet and exercise is associated with better control, …
Direct synthesis using gold atoms. Monodioxygen gold, Au(O2) (1976)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDirect synthesis using gold atoms. Monodioxygen gold, Au(O2)D. McIntosh and G. A. OzinCite this: Inorg. Chem. 1976, 15, 11, 2869–2871Publication Date (Print):November 1, 1976Publication History Published online1 May 2002Published inissue 1 November 1976https://pubs.acs.org/doi/10.1021/ic50165a063https://doi.org/10.1021/ic50165a063research-articleACS PublicationsRequest reuse permissionsArticle Views135Altmetric-Citations49LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Ab initio characterization and experimental validation on the roles of oxygen-containing groups in graphene based formaldehyde sensors (2017)

The development of formaldehyde (HCHO) sensors employing reduced graphene oxide (rGO) as sensing materials calls for a profound, atomic level understanding on the roles of oxygen-containing groups. In this work, the performances of rGO-based HCHO sensors were investigated using ab initio calculations and experimental validation. Density functional theory (DFT) simulations were performed to calculate the adsorption energy (E<sub>ads</sub>) and charge transfer (ΔQ) for the adsorption of HCHO on pristine graphene, rGO with epoxides, rGO with hydroxyl groups, and rGO with carboxyl groups. The results show that the incorporation of oxygen-containing groups leads to an obvious increase of E<sub>ads</sub> and ΔQ values, with an order of carboxyl group > hydroxyl group > epoxides > pristine graphene. The increase of E<sub>ads</sub> and ΔQ values could increase the variation in the concentration of charge carriers, the change of conductance of the sensing materials, and hence the sensor response. The experimental measurements indicate that with a decrease in the C/O atomic ratio from 16.2 to 6.6, the sensor response to 1 ppm HCHO increases from 0.10% to 0.73%, confirming the DFT calculation results. Moreover, even with a certain C/O atomic ratio of ∼6.6, rGO with 6.80% carboxyl groups exhibits a distinctly larger response to 0.2-3 ppm HCHO, compared with the counterpart with 3.09% carboxyl groups. The as-obtained insights into the effects of oxygen-containing groups on the response of rGO to HCHO could be instructive for preparing rGO-based HCHO sensors for advanced performances.
Field-aware Factorization Machines in a Real-world Online Advertising System (2017)

Predicting user response is one of the core machine learning tasks in computational advertising. Field-aware Factorization Machines (FFM) have recently been established as a state-of-the-art method for that problem and in particular won two Kaggle challenges. This paper presents some results from implementing this method in a production system that predicts click-through and conversion rates for display advertising and shows that this method it is not only effective to win challenges but is also valuable in a real-world prediction system. We also discuss some specific challenges and solutions to reduce the training time, namely the use of an innovative seeding algorithm and a distributed learning mechanism.
Analyzing Reduction Abstractions Capabilities (2021)

Reductions are a common pattern in parallel programming, and every parallel programming language or framework has its own reduction abstraction with its own idiosyncrasies. These abstractions differ not only in their syntax, but also in their semantics and their ability to express certain types of reduction. Such differences may prevent specific combinations of abstraction and hardware platform from reaching high levels of performance, with consequences for portability and programmer productivity.<br/><br/>In this paper, we present a set of representative reduction benchmarks to explore the capabilities of five contemporary programming languages and frameworks -- OpenMP, Kokkos, RAJA, SYCL, and the oneAPI DPC++ Library (oneDPL) -- across a variety of hardware platforms, including CPUs and GPUs from multiple vendors. We discuss the advantages and disadvantages of each reduction abstraction, and conclude with recommendations to improve their design and implementation.
Supplementary Figure 6 from Therapeutic and Prophylactic Antitumor Activity of an Oral Inhibitor of Fucosylation in Spontaneous Mammary Cancers (2023)

&lt;p&gt;Weights were collected from n=7 to 20 TgMMTV-neu mice per group at various times throughout the study; average weight is represented over age of untreated (circle), 20mM 2FF (square) and 50mM 2FF (triangle) treated mice. The solid gray arrow represents end of 50mM 2FF treatment, dashed black arrow represents end of 20mM 2FF treatment.&lt;/p&gt;
Transcutaneous Ultrasound Augments Naked DNA Transfection of Skeletal Muscle (2002)

This study was designed to test the hypothesis that transcutaneous ultrasound (US) exposure may augment the transfection efficiency and biological outcome associated with nonviral DNA gene transfer. Hindlimb muscles of New Zealand White rabbits were transfected with the reporter plasmid pCMV-β, with or without US exposure. Optimization studies employed US exposure at various frequencies, mechanical indices, duty cycles, durations of exposure, and exposure time points. Based on these results, we explored the effect of US exposure on nonviral gene transfer of vascular endothelial growth factor (VEGF, phVEGF165) to promote neovascularization of ischemic hindlimbs. Ultrasound at 1 MHz, 100 W/cm2, 6% duty cycle, and 5 minutes exposure time, applied immediately following DNA injection, was found to be the most effective among the settings tested, increasing β-galactosidase expression ∼20 fold. Compared with US exposure alone, or phVEGF165 only, phVEGF165 + US exposure yielded a statistically significant improvement in revascularization, as determined by calf blood pressure ratio, angiographic score, intravascular Doppler blood flow, and capillary/myocyte ratio. These data demonstrate that ultrasound, when applied directly after intramuscular gene transfer, significantly increases transfection efficiency in vivo. The biological significance of this finding was confirmed by augmented limb perfusion in response to US exposure and naked VEGF DNA.
Linguistics, the first fifty years … and a little more (2013)

This special issue is a very special issue. It celebrates the journal's fiftieth anniversary, and to that purpose we are reprinting five of its most important articles, one for each decade. For its sixth decade we include an article that was going to be published, in a regular fashion, but in the end never was, because the author passed away. In Section 3 these six articles are put into a wider perspective. Sections 1 and 2 describe how the journal came into existence in the fifties and how it underwent a facelift in the late seventies.
Spectroscopic studies of photosensitization in solutions and in cells (1995)

We employ classical porphyrins, as well as second-generation sensitizers, such as tetrabenzo- porphyrins, naphthaloporphyrins, texaphyrins, and sapphyrins for biological photosensitization. We studied the extent of sensitizer binding to biological membranes and bacterial cells; the singlet oxygen production yield in homogeneous solutions and in membranes; and the efficiency of the photo-cytotoxic effect of the sensitizers. In carrying out these studies, absorption and fluorescence spectra were used as monitoring techniques. We demonstrate a spectroscopic probing procedure, based on the well established chemical quencher of singlet oxygen, DPIBF, which at appropriate concentration allows a simple mathematical evaluation of the absolute quantum yield of singlet oxygen production. The method does not rely on any predetermined kinetic values and provides a result with high accuracy. The relative efficiency of competing photochemical processes in cells was established, so that the likely mechanism which is responsible for the death of the cell could be pointed out. A unique and exceptional wavelength dependence of photophysical properties is described.
Bronchial wall parameters on CT in healthy never-smoking, smoking, COPD, and asthma populations: a systematic review and meta-analysis (2022)

• Diverse methodology in measuring airways contributes to overlap in ranges of bronchial parameters among the never-smoking, smoking, COPD, and asthma populations. • The combined number of never-smoking participants in studies is low, limiting insight into this population and the impact of participant characteristics on bronchial parameters. • Wall area percent of the right upper lobe apical segment is the most studied (87 articles) and differentiates all except smoking vs asthma populations.
Cognitive Radio in a Frequency Planned Environment: Can it Work? (2007)

The objective of this work is to assess some fundamental limits of operation for cognitive radios in a frequency- planned environment. We present a first-order analysis of the carrier-to-noise-and-interference situation in a cellular wireless network, and analyze the impact of cognitive users starting to transmit. The main conclusion is that introducing cognitive transmitters in a frequency-planned cellular network without causing substantial interference is very challenging.