gebhart/patrepeval huggingface dataset:
Biogenetic-type total synthesis. dl-Tetrahymanol (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBiogenetic-type total synthesis. dl-TetrahymanolE. E. Van Tamelen, R. A. Holton, R. E. Hopla, and W. E. KonzCite this: J. Am. Chem. Soc. 1972, 94, 23, 8228–8229Publication Date (Print):November 1, 1972Publication History Published online1 May 2002Published inissue 1 November 1972https://pubs.acs.org/doi/10.1021/ja00778a048https://doi.org/10.1021/ja00778a048research-articleACS PublicationsRequest reuse permissionsArticle Views215Altmetric-Citations23LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Novel pressure-gradient driven component for blood extraction (2005)

Portable blood analysis devices are usually appreciable for applications in blood diagnostic system. We have designed and fabricated a low-cost and simple deal blood extraction device for a biomedical analysis. The device mainly composes of blood extraction tool and a functional bio-chemical analyzing element. In this work, we report the fabrication and pressure-gradient testing results of the blood extraction tool which consists of painless microneedle array and pressure-gradient tank. Microneedle array was fabricated by X-ray lithography using PCT (Plane-pattern to Cross-section Transfer) technique. The idea of our extraction device was simple but capability which is just to hold a sufficient pressure gradient between the tank and blood vessel. The device can draw the volume of blood up to 237 &#956;l. The device was made of low-cost and disposable materials since it is expected to be used for single blood analysis system. In this work, we introduce design, fabrication and mechanism of the pressure gradient driven component including the extraction test results. The fabrication method of microneedle used in our system is also described.
Role of humidity in oxidation of ultrathin GaSe (2019)

The oxidation mechanisms of exfoliated Gallium Selenide (GaSe) are strongly influenced by humidity. We have observed that the presence of water molecules leads to formation of Ga<sub>2</sub>O<sub>3</sub>, SeO<sub>2</sub>, and Se via sequence of intermediate reactions which include generation of aqueous solution of selenic acid. Raman spectra of GaSe flakes undergoing oxidation in a humidity-controlled environment reveal formation of selenic acid-related species causing Raman scattering signal in the regions around 830 cm<sup>-1</sup> and around 1230 cm<sup>-1</sup>. This observation sheds light on the path of chemical reactions, going via an intermediate stage of formation of gallium hydroxide and selenium oxide-water complexes with further decompositions of these compounds to Ga<sub>2</sub>O<sub>3</sub>, SeO<sub>2</sub>, and amorphous selenium.
Dendritic cells govern induction and reprogramming of polarized tissue‐selective homing receptor patterns of T cells: important roles for soluble factors and tissue microenvironments (2005)

Tissue-selective homing is established during naive T cell activation by the tissue microenvironment and tissue-specific dendritic cells (DC). The factors driving induction and maintenance of T cell homing patterns are still largely unknown. Here we show that soluble factors produced during the interaction of T cells with CD11c(+) DC isolated from skin- or small intestine-associated tissues differentially modulate expression of the corresponding tissue-selective homing receptors (E-selectin ligands and alpha4beta7 integrin/CCR9, respectively) on murine CD8(+) T cells. Injection of tissue-specific DC via different routes induces T cells with homing receptors characteristic of the corresponding local tissue microenvironment, independent of the origin of the DC. These data indicate an important role for signals delivered in trans. Moreover, DC can reprogram the homing receptor expression on T cells previously polarized in vitro for homing to skin or small intestine. Importantly, skin-homing memory T cells stimulated directly ex vivo can also be reprogrammed by intestinal DC to a gut-homing phenotype. Our results show that tissue-selective homing receptor expression on effector and memory T cells is governed by inductive as well as suppressive signals from both DC and tissue microenvironments.
A variational dynamic programming approach to robot-path planning with a distance-safety criterion (1988)

An approach to robot-path planning is developed by considering both the traveling distance and the safety of the robot. A computationally-efficient algorithm is developed to find a near-optimal path with a weighted distance-safety criterion by using a variational calculus and dynamic programming (VCDP) method. The algorithm is readily applicable to any factory environment by representing the free workspace as channels. A method for deriving these channels is also proposed. Although it is developed mainly for two-dimensional problems, this method can be easily extended to a class of three-dimensional problems. Numerical examples are presented to demonstrate the utility and power of this method.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Smooth quality adaptation method for VBR video streaming over HTTP (2015)

In adaptive video streaming, rate adaptation is an important procedure for switching between different representations provided at the server, to cope with the network fluctuations. However, most of adaptation methods ever since mainly focus on the case of constant bitrate (CBR) video. In this paper, we present a new method that can effectively support variable bitrate (VBR) videos. Our method is buffer-based, where the buffer thresholds are dynamically controlled to cope with bandwidth behavior as well as changes in video content. The experiment results show that our method performs well under different scenarios of bandwidth fluctuations.
Small-Variance Asymptotics for Dirichlet Process Mixtures of SVMs (2014)

Infinite SVM (iSVM) is a Dirichlet process (DP) mixture of large-margin classifiers. Though flexible in learning nonlinear classifiers and discovering latent clustering structures, iSVM has a difficult inference task and existing methods could hinder its applicability to large-scale problems. This paper presents a small-variance asymptotic analysis to derive a simple and efficient algorithm, which monotonically optimizes a max-margin DP-means (M2DPM) problem, an extension of DP-means for both predictive learning and descriptive clustering. Our analysis is built on Gibbs infinite SVMs, an alternative DP mixture of large-margin machines, which admits a partially collapsed Gibbs sampler without truncation by exploring data augmentation techniques. Experimental results show that M2DPM runs much faster than similar algorithms without sacrificing prediction accuracies.
Supplementary Figures 1-11 from Allogeneic Human Double Negative T Cells as a Novel Immunotherapy for Acute Myeloid Leukemia and Its Underlying Mechanisms (2023)

&lt;p&gt;Figure S1. Characterization of ex vivo expanded healthy donor (HD) DNTs; Figure S2. Allogeneic DNTs induce dose- and time- dependent cytotoxicity against leukemic cells; Figure S3. Correlation between the susceptibility of AML patient blasts to DNT-mediated cytotoxicity and clinical features; Figure S4. Potency of anti-leukemic function mediated by allogeneic DNTs; Figure S5. Cytotoxic function of allogeneic DNTs on normal peripheral blood myeloid cells; Figure S6. NKp30, NKp44, and NKp46 are not involved in DNT-mediated killing of AML; Figure S7. Level of IFNγ production by DNTs corresponds with the level of cytotoxicity mediated by DNTs; Figure S8. DNAM-1 and NKG2D blocking abrogates IFNγ production by DNTs; Figure S9. IFNγ treatment does not affect the NKG2D and DNAM-1 ligand expression on normal PBMC; Figure S10. Cytotoxic activity of DNTs against leukemia cell lines derived from different types of leukemia and lymphoma; Figure S11. Effect of cryopreservation on the viability and anti-leukemic activity of ex vivo expanded DNTs.&lt;/p&gt;
Cone-Beam Tomography with Linearly Distorted Source Trajectories (2006)

A major drawback of Katsevich's exact general cone-beam inversion scheme is the difficulty in finding practical algorithms adapted to every novel type of source trajectory. We succeeded to overcome this problem, and can formulate reconstruction algorithms, for trajectories that are related through a linear distortion to an already studied scenario. The introduced theory yields two reconstruction strategies that are in principle independent from the underlying reconstruction algorithm and are either based on data pre- and post-processing or on adjustment of filtering directions. Numerical results based on simulated cone-beam data are presented.
Improving the performance of Pd based catalysts for the direct synthesis of hydrogen peroxide via acid incorporation during catalyst synthesis (2021)

The direct synthesis of hydrogen peroxide from molecular H2 and O2 offers an attractive alternative to the current means of production of this powerful oxidant, on an industrial scale. Herein we investigate the role of nitric acid addition, during catalyst preparation as a means of improving catalytic performance, under reaction conditions that have previously been found to be optimal for H2O2 production. The addition of dilute nitric acid during catalyst preparation is found to lead to a significant improvement in H2O2 synthesis activity, through the modification of particle size and control of Pd oxidation state.
Search for new physics in events with same-sign dileptons and b jets in pp collisions at $ \sqrt{s}=8 $ TeV (2013)

A bstract A search for new physics is performed using events with isolated same-sign leptons and at least two bottom-quark jets in the final state. Results are based on a sample of proton-proton collisions collected at a center-of-mass energy of 8 TeV with the CMS detector and corresponding to an integrated luminosity of 10.5 fb −1 . No excess above the standard model background is observed. Upper limits are set on the number of events from non-standard-model sources and are used to constrain a number of new physics models. Information on acceptance and efficiencies is also provided so that the results can be used to confront an even broader class of new physics models.
Low Consumption Balanced Front-End Amplifiers Robust to Load Variations in 65nm PD-SOI CMOS Technology for 60 GHz Short-Range Wireless Applications (2022)

This brief presents two low consumption balanced front-end amplifiers designed in 65nm PD-SOI CMOS technology dedicated to low output power 60 GHz short-range wireless applications. For both designs, a resistive feedback neutralized common source differential pair architecture is used with 90° twisted hybrid couplers which allows power combining in addition to an improved robustness against load variations shown by load-pull experimental results. A specific design approach is used to reduce power consumption and limit the output power level. The one-stage amplifier exhibits a gain of 5.43 dB, an OCP1dB of 4.5 dBm, a saturated power superior to 6.33 dBm and a peak PAE of 8.6 % for a total power consumption of solely 14 mW and an active area of 0.17 mm2. The three-stage amplifier exhibits a gain of 21 dB, an OCP1dB of 3.7 dBm, a <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${\mathbf {P}}_{\mathbf {sat}}$ </tex-math></inline-formula> of 7 dBm and a peak PAE of 8.4 % under a total power consumption of only 42 mW and an active area of 0.3 mm2. All the reported performances are obtained at 60 GHz from a 1V supply voltage.
Surveillance of Burn Wound Infections: A Proposal for Definitions (1998)

The diagnosis of burn wound infections is a subjective art, with no recent attempts to standardize or validate the definitions of terms used to discuss such infections. The Centers for Disease Control included definitions of types of burn wound infections in its definitions for nosocomial infections in 1988. Although the other Centers for Disease Control criteria for nosocomial infections have epidemiological applications, its criteria for burn wound infections have neither clinical nor epidemiological value to burn centers and their health care providers. With the approval of the Board of Trustees of the American Burn Association, the authors of this article formed a working subcommittee of the Committee on the Organization and Delivery of Burn Care. Definitions of burn wound infections are presented for consideration for application in either of 2 areas: (1) surveillance of burn wound infections in burn centers and (2) standardized criteria for multicenter clinical trials or national registries.
High Magnetoresistance in Fully Epitaxial Magnetic Tunnel Junctions with a SemiconductingGaOxTunnel Barrier (2016)

The spin field-effect transistor (spin-FET) is the ultimate spintronic device, and the ultimate issue for spin-FET technology is realizing a high magnetoresistance (MR) ratio in a ferromagnet/semiconductor/ferromagnet sandwich. The authors succeed in fabricating fully epitaxial Fe/GaO${}_{x}$/Fe magnetic tunnel junctions with MR ratios up to 92% at room temperature---a milestone in the development of spin-FETs in a vertical, rather than planar, configuration.
Pristine and hydrated fluoroapatite (0001) (2019)

The surface structure of fluoroapatite (0001) (FAp<sub>0001</sub>) under quasi-dry and humid conditions has been probed with surface X-ray diffraction (SXRD). Lateral and perpendicular atomic relaxations corresponding to the FAp<sub>0001</sub> termination before and after H<sub>2</sub>O exposure and the location of the adsorbed water molecules have been determined from experimental analysis of the crystal truncation rod (CTR) intensities. The surface under dry conditions exhibits a bulk termination with relaxations in the outermost atomic layers. The hydrated surface is formed by a disordered partially occupied H<sub>2</sub>O layer containing one water molecule (33% surface coverage) adsorbed at each of the three surface Ca atoms, and is coupled with one OH group randomly bonded to each of the three topmost P atoms with a 33% surface coverage.
Process modeling of the low‐temperature evolution and yield of polycarbosilanes for ceramic matrix composites (2018)

Abstract The volatilization of polycarbosilanes is important to the processing and performance of polymer infiltration and pyrolysis‐based ceramic matrix composites. Low molecular weight ( MW ) polycarbosilane is often present in preceramic polymers and enhances viscosity for the purpose of composite infiltration. Due to the volatility of low MW chains, a model was developed to semi‐empirically determine the MW distribution and then predict the mass yield and evolution of the MW distribution as a function of temperature and time for Star PCS ™ SMP ‐10. The enthalpy of vaporization, the temperature dependence of the enthalpy of vaporization, the temperature dependence of the normal boiling point and a representation of the molecular weight distribution were fit using a series of thermogravimetric measurements, involving isothermal holds on a particular batch of SMP ‐10. Once calibrated for SMP ‐10 in this fashion, the molecular weight distribution of different batches of SMP ‐10 could be fit using a thermogravimetric measurement involving a reduced temperature‐time series. The model was then predictive of mass loss over time for temperatures below the onset of curing (&gt;90°C). Understanding this volatilization enables improved SiC yield, reduced processing time and minimizing void/bubble formation.
Excitation light source dependence of emission in Sn2+-Ce3+ codoped ZnO-P2O5 glasses (2013)

Correlation between excitation light source and the emission property of Sn2+-Ce3+ co-doped zinc phosphate glasses is examined. Although photoluminescence (PL) peaks of both Sn2+ and Ce3+ shifted with increasing amount of Ce3+, there was little energy resonance between Sn2+ and Ce3+ emission centers. On the other hand, radioluminescence (RL) spectra excited by X-ray was independent of the Ce concentration, indicating that emission was mainly observed from Sn2+ emission center. It is expected that energy relaxation process in a RL preferentially occurs in an ns2-type emission center that possesses high transition probability of the excited state in the higher energy region.
A Key-Recovery Attack on SOBER-128 (2007)

In this talk we consider linear approximations of layered cipher constructions with secret key-dependent constants that are inserted between layers, and where the layers have strong interdependency. Then clearly, averaging over the constant would clearly be wrong as it will break the interdependencies, and the Piling Up-lemma cannot be used. We show how to use linear approximations to divide the constants into constant classes, not necessary determined by a linear relation. As an example, a nonlinear filter generator SOBER-128 is considered and we show how to extend Matsui's Algorithm I in this case. Also the possibility of using multiple linear approximations simultaneously is considered.
Supplementary Data from Yes-Associated Protein 1 Exhibits Oncogenic Property in Gastric Cancer and Its Nuclear Accumulation Associates with Poor Prognosis (2023)

&lt;p&gt;Supplementary Figures S1-S5; Supplementary Tables S1-S4.&lt;/p&gt;
Laboratory demonstration and characterization of phase-sorting interferometry (2012)

Non-common path (NCP) errors that lie downstream from the wavefront sensor (WFS) in an AO setup can’t be directly corrected by the WFS and end up altering the science images by introducing quasi-static speckles. These speckles impose limits to the direct imaging of exoplanets, debris disks and other objects for which we require high contrast. Phase-sorting interferometry (PSI) uses WFS residuals as interferometric probes to the speckles. With the retrieved amplitude and phase the deformable mirror can be adjusted to remove the speckles. Previously PSI has been demonstrated to correct -to first order- the non-common path error on-sky at the MMTO in Arizona. We present an AO laboratory testbed and the techniques used to determine the properties of PSI; the influence of the time synchronisation between WFS and science camera, the achromacity of the atmosphere and other limiting factors. Furthermore we test the performance of the PSI method when coronagraphs such as apodizing phase plates, Lyot masks and 4QPMs are introduced to the setup. Lastly this setup enables us to rapidly prototype high-contrast imaging techniques.
A safe and sustainable bacterial cellulose nanofiber separator for lithium rechargeable batteries (2019)

Bacterial cellulose nanofiber (BCNF) with high thermal stability produced by an ecofriendly process has emerged as a promising solution to realize safe and sustainable materials in the large-scale battery. However, an understanding of the actual thermal behavior of the BCNF in the full-cell battery has been lacking, and the yield is still limited for commercialization. Here, we report the entire process of BCNF production and battery manufacture. We systematically constructed a strain with the highest yield (31.5%) by increasing metabolic flux and improved safety by introducing a Lewis base to overcome thermochemical degradation in the battery. This report will open ways of exploiting the BCNF as a "single-layer" separator, a good alternative to the existing chemical-derived one, and thus can greatly contribute to solving the environmental and safety issues.
Laser Scattering Microhaze Correlation with Polysilicon Surface Roughness and Impact on Electrical Performance (2006)

Laser scattering surface maps of polysilicon films are studied under a range of process conditions. The surface maps are shown to contain information that correlates with polysilicon film morphology which impacts device performance within a CMOS process for the 45 nm node. These surface maps provide whole wafer surface information at a data collection throughput of 1 minute per wafer. They provide a novel and rapid methodology for process tool monitoring that can enhance the line stability.
Quantification and Classification of E. coli Proteome Utilization and Unused Protein Costs across Environments (2016)

The costs and benefits of protein expression are balanced through evolution. Expression of un-utilized protein (that have no benefits in the current environment) incurs a quantifiable fitness costs on cellular growth rates; however, the magnitude and variability of un-utilized protein expression in natural settings is unknown, largely due to the challenge in determining environment-specific proteome utilization. We address this challenge using absolute and global proteomics data combined with a recently developed genome-scale model of Escherichia coli that computes the environment-specific cost and utility of the proteome on a per gene basis. We show that nearly half of the proteome mass is unused in certain environments and accounting for the cost of this unused protein expression explains >95% of the variance in growth rates of Escherichia coli across 16 distinct environments. Furthermore, reduction in unused protein expression is shown to be a common mechanism to increase cellular growth rates in adaptive evolution experiments. Classification of the unused protein reveals that the unused protein encodes several nutrient- and stress- preparedness functions, which may convey fitness benefits in varying environments. Thus, unused protein expression is the source of large and pervasive fitness costs that may provide the benefit of hedging against environmental change.