gebhart/patrepeval huggingface dataset:
A Low-Noise Fractional-<inline-formula> <tex-math notation="LaTeX">${N}$ </tex-math> </inline-formula> Digital Frequency Synthesizer With Implicit Frequency Tripling for mm-Wave Applications (2018)

In this paper, we propose a 60-GHz fractional- <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">${N}$ </tex-math></inline-formula> digital frequency synthesizer aimed at reducing its phase noise (PN) at both the flicker ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$1/\!f^{3}$ </tex-math></inline-formula> ) and thermal ( <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$1/\!f^{2}$ </tex-math></inline-formula> ) regions while minimizing its power consumption. The digitally controlled oscillator (DCO) fundamentally resonates at 20 GHz and co-generates a strong third harmonic at 60 GHz which is extracted to the output while canceling the 20-GHz fundamental. The latter component is fed back to the frequency dividers in an all-digital phase-locked loop for phase detection, which comprises a pair of digital-to-time and time-to-digital converters with <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\Sigma \Delta $ </tex-math></inline-formula> dithering to attenuate fractional spurs. The mechanism of flicker noise upconversion to <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$1/\!f^{3}$ </tex-math></inline-formula> PN in the DCO is investigated, and a reduction technique is proposed. The 28-nm CMOS prototype achieves 213–277-fs rms jitter in the 57.5–67.2-GHz tuning range while consuming only 40 mW. The DCO flicker PN corner is record low at 300–400 kHz.
The androgenic regulation of the activities of enzymes engaged in the synthesis of deoxyribonucleic acid in rat ventral prostate gland (1975)

The restoration of mitosis and growth of the prostate gland of castrated animals by androgens provides a favourable experimental system for studying the hormonal regulation of enzymes engaged in DNA replication. 2. Many DNA polymerase activities were identified in the prostate gland, but only a 9S form with a particular preference for denatured DNA as template was conspicuously enhanced by androgenic stimulation. 3. Thymidine kinase also provided a sensitive indicator of the hormonal regulation of DNA replication, and on electrophoretic criteria, one discrete form of the enzyme appeared precisely with the onset of mitoris. 4. Evidence is presented to support the view that DNA ligase activity is intimately associated in the process of DNA replication in the prostate gland. 5. A spectrum of deoxyribonuclease activities is present in the prostate gland, but only one form (pI7.0) can safely be said to be implicated in the process of DNA replication. 6. Androgenic stimulation of the prostate gland leads to the appearance of a component capable of denaturing or unwinding prostate DNA. This component is seemingly distinct from RNA or DNA polymerase activities on the basis of several distince physicochemical characteristics. 7. The conspicuous feature of all the changes in enzyme activities evoked by androgens in the prostate gland is their acute tissue- and steroid-specificity. Such changes could not be mimicked in liver or spleen and the regulatory role of androgens could not be simulated by other classes of steroid hormones. Particularly on the basis of studies with the anti-androgen cyproterone acetate, it is concluded that the changes are initially mediated by the androgen-receptor system and the high-affinity binding of 5alpha-dihydrotestosterone in the prostate gland. 8. The results are discussed in the context of the mechanism of action of androgens.
Monitoring and Fault Detection in Photovoltaic Systems Based On Inverter Measured String I-V Curves (2015)

Most photovoltaic (PV) string inverters have the hardware capability to measure at least part of the current-voltage (I-V) characteristic curve of the PV strings connected at the input. However, this intrinsic capability of the inverters is not used, since I-V curve measurement and monitoring functions are not implemented in the inverter control software. In this paper, we aim to show how such a functionality can be useful for PV system monitoring purposes, to detect the presence and cause of power-loss in the PV strings, be it due to shading, degradation of the PV modules or balance-of-system components through increased series resistance losses, or shunting of the PV modules. To achieve this, we propose and experimentally demonstrate three complementary PV system monitoring methods that make use of the I-V curve measurement capability of a commercial string inverter. The first method is suitable for monitoring single or independent PV strings, and is based on evaluating the ratio of certain operation points on the string I-V curve. The second method is applicable to PV systems with identical strings, and is based on monitoring and inter-comparison of string I-V curve parameters. For PV systems with non-identical strings, or when all strings can be affected by faults, we propose to use in-plane irradiance and module temperature measurements, and a performance model of the PV strings, to predict the optimal string I-V curve parameters, and then perform the inter-comparison with the measured values, to identify the cause of the faults.
Oxidation of alcohols using supported gold and gold–palladium nanoparticles (2009)

A key discovery in the last two decades has been the realisation that gold, when prepared as supported nanoparticles, is exceptionally effective as an oxidation catalyst, particularly for the oxidation of carbon monoxide at sub-ambient temperature but also for a number of organic reactions of synthetic significance. To some extent this observation is counterintuitive since extended gold surfaces do not chemisorb oxygen, nor do they corrode. For some oxidation reactions, the catalytic activity is markedly enhanced by the addition of palladium. This paper is concerned with recent advances in understanding the mechanism of catalysis by gold–palladium alloy nanoparticles of one such organic reaction, the oxidation of alcohols to the corresponding carbonyl compounds by molecular oxygen. We report detailed reaction studies using a high activity catalyst prepared by sol-immobilisation on a titania support. Using solvent-free conditions, benzyl alcohol is oxidised primarily to benzaldehyde but small amounts of toluene are also formed. The origin of these products is explored using initial rate measurements, deuterium labelling and kinetic isotope effects, and by the study of substituent effects. The effect of changing the nature of the catalyst support is also briefly examined. On the basis of all the results, we consider that we have evidence for multiple reaction pathways in this heterogeneous system. We put forward general mechanisms for the overall processes and describe confirmatory experiments in support of these, and we suggest possible reaction intermediates involved in the heterogeneously catalysed reaction.
Observation of the decay Bs0→D¯0K+K− (2018)

The first observation of the B 0 s D0 K K -decay is reported, together with the most precise branching fraction measurement of the mode B 0 D0 K K -. The results are obtained from an analysis of pp collision data corresponding to an integrated luminosity of 3.0 fb -1 . The data were collected with the LHCb detector at center-of-mass energies of 7 and 8 TeV. The branching fraction of the
Dose-response and ghosting effects of an amorphous silicon electronic portal imaging device (2003)

The purpose of this study was to investigate the dose-response characteristics, including ghosting effects, of an amorphous silicon-based electronic portal imaging device (a-Si EPID) under clinical conditions. EPID measurements were performed using one prototype and two commercial a-Si detectors on two linear accelerators: one with 4 and 6 MV and the other with 8 and 18 MV x-ray beams. First, the EPID signal and ionization chamber measurements in a mini-phantom were compared to determine the amount of buildup required for EPID dosimetry. Subsequently, EPID signal characteristics were studied as a function of dose per pulse, pulse repetition frequency (PRF) and total dose, as well as the effects of ghosting. There was an over-response of the EPID signal compared to the ionization chamber of up to 18%, with no additional buildup layer over an air gap range of 10 to 60 cm. The addition of a 2.5 mm thick copper plate sufficiently reduced this over-response to within 1% at clinically relevant patient-detector air gaps (> 40 cm). The response of the EPIDs varied by up to 8% over a large range of dose per pulse values, PRF values and number of monitor units. The EPID response showed an under-response at shorter beam times due to ghosting effects, which depended on the number of exposure frames for a fixed frame acquisition rate. With an appropriate build-up layer and corrections for dose per pulse, PRF and ghosting, the variation in the a-Si EPID response can be reduced to well within +/- 1%.
Robotic Implantation of a Multichamber Cardiac Resynchronization Therapy Defibrillator (2006)

Transvenous implantation of a cardiac resynchronization therapy defibrillator (CRT-D) may not be feasible due to anatomic constraints. One of the most notable advances in minimal-access heart surgery has been the introduction of robotic telemanipulation systems. We present a challenging case in which a CRT-D system was implanted using a robotic approach. Feasibility of such an approach expands the horizons for delivery of CRT-D therapy.
Development of a Planar Array Infrared Reflection Spectrograph for Reflection—Absorption Spectroscopy of Thin Films at Metal and Water Surfaces (2007)

Planar array infrared (PA-IR) spectroscopy offers several advantages over Fourier transform infrared (FT-IR) methods, including ultrafast speed (<100 micros temporal resolution) and excellent sensitivity. However, obtaining spectra in the range of 1800 to 1000 cm(-1) of films at the air-water interface remains difficult due to the poor IR reflectivity of water, the extremely low concentration of the thin film on the water subphase, and the interference of water bands. In this study, we report a new planar array infrared reflection spectrograph (PA-IRRS), which has several advantages over conventional approaches. This instrument can record sample and reference spectra simultaneously with an instrumental setup that is the same as that of a single-beam instrument by splitting the incident infrared beam into two sections on a plane mirror (H) or a water trough. With this design, the instrument can accommodate large infrared accessories, such as a water trough, without a loss of infrared beam intensity. Water bands can be subtracted to obtain a high-quality spectrum for poly(L-lactic acid) Langmuir film on the water subphase with a resolution of about 6 cm(-1) in 10.8 s. Hence, this PA-IRRS system has great potential for investigating the time-resolved dynamics of a broad range of Langmuir films, such as cellular membranes or biopolymers, on the water subphase.
Masking Kyber: First- and Higher-Order Implementations (2021)

In the final phase of the post-quantum cryptography standardization effort, the focus has been extended to include the side-channel resistance of the candidates. While some schemes have been already extensively analyzed in this regard, there is no such study yet of the finalist Kyber.In this work, we demonstrate the first completely masked implementation of Kyber which is protected against first- and higher-order attacks. To the best of our knowledge, this results in the first higher-order masked implementation of any post-quantum secure key encapsulation mechanism algorithm. This is realized by introducing two new techniques. First, we propose a higher-order algorithm for the one-bit compression operation. This is based on a masked bit-sliced binary-search that can be applied to prime moduli. Second, we propose a technique which enables one to compare uncompressed masked polynomials with compressed public polynomials. This avoids the costly masking of the ciphertext compression while being able to be instantiated at arbitrary orders.We show performance results for first-, second- and third-order protected implementations on the Arm Cortex-M0+ and Cortex-M4F. Notably, our implementation of first-order masked Kyber decapsulation requires 3.1 million cycles on the Cortex-M4F. This is a factor 3.5 overhead compared to the unprotected optimized implementationin pqm4. We experimentally show that the first-order implementation of our new modules on the Cortex-M0+ is hardened against attacks using 100 000 traces and mechanically verify the security in a fine-grained leakage model using the verification tool scVerif.
Multi-Gigabit communication: the ADC bottleneck<sup>1</sup> (2009)

The economies of scale in modern communication systems are enabled by architectures that take advantage of Moore's law to implement most transceiver functionalities in digital signal processing (DSP). The bottleneck in scaling such ldquomostly digitalrdquo architectures to multi-Gigabit rates becomes the analog-to-digital converter (ADC): high-speed, high-precision ADCs are either not available, or are too costly and power-hungry. In this paper, we report on recent results on two approaches towards addressing this bottleneck. The first is to simply use drastically low-precision (1-4 bit) ADCs than current practice. This could be suitable for applications that require limited dynamic range (e.g., line-of-sight communication using small constellations), but there are fundamental and algorithmic questions as to whether all the functions of a communication receiver can be realized with such a significant nonlinearity early in the processing. The second is to use a time-interleaved ADC, where a large number of low-speed, high-precision ADCs are employed in parallel to realize a high-speed, high-precision ADC. This is more generally applicable to applications requiring large dynamic range (e.g., large constellations and/or dispersive channels), but the important question is how to effectively address the mismatch between the component ADCs, which leads to a performance floor if left uncompensated.
Modulating the Electron–Hole Interaction in a Hybrid Lead Halide Perovskite with an Electric Field (2015)

Despite rapid developments in both photovoltaic and light-emitting device performance, the understanding of the optoelectronic properties of hybrid lead halide perovskites is still incomplete. In particular, the polarizability of the material, the presence of molecular dipoles, and their influence on the dynamics of the photoexcitations remain an open issue to be clarified. Here, we investigate the effect of an applied external electric field on the photoexcited species of CH3NH3PbI3 thin films, both at room temperature and at low temperature, by monitoring the photoluminescence (PL) yield and PL decays. At room temperature we find evidence for electric-field-induced reduction of radiative bimolecular carrier recombination together with motion of charged defects that affects the nonradiative decay rate of the photoexcited species. At low temperature (190 K), we observe a field-induced enhancement of radiative free carrier recombination rates that lasts even after the removal of the field. We assign this to field-induced alignment of the molecular dipoles, which reduces the vibrational freedom of the lattice and the associated local screening and hence results in a stronger electron-hole interaction.
A nonlinear beam finite element for curved and twisted composite helicopter blade (2009)

International audience
Comparison of retention characteristics of ferroelectric capacitors with Pb(Zr, Ti)O₃ films deposited by various methods for high-density non-volatile memory (2003)

We investigated the polarization retention characteristics of ferroelectric capacitors with (PZT) thin films which were fabricated by different deposition methods. In thermally-accelerated retention tests, PZT films which were prepared by a chemical solution deposition (CSD) method showed rapid decay of retained polarization charges as the thickness of the films decreased down to 100 nm, while the films which were grown by metal organic chemical vapor deposition (MOCVD) retained relatively large non-volatile charges at the corresponding thickness. We concluded that in the CSD-grown films, the thicker interfacial passive layer compared with the MOCVD-grown films had an unfavorable effect on retention behavior. We observed the existence of such interfacial layers by extrapolation of the total capacitance with thickness of the films and the capacitance of these layers was larger in MOCVD-grown films than in CSD-grown films. Due to incomplete compensation of surface polarization charges by the free charges in the metal electrodes, the interfacial field activated the space charges inside the interfacial layers and deposited them at the boundary between the ferroelectric layer and the interfacial layer. Such space charges built up an internal field inside the films, which interfered with domain wall motion, so that retention property at last became degraded. We observed less imprint which was a result of less internal field in MOCVD-grown films while large imprint was observed in CSD-grown films.
Breathing-Compensated Neural Networks for Real Time C-Arm Pose Estimation in Lung CT-Fluoroscopy Registration (2022)

Augmentation of interventional c-arm fluoroscopy using information extracted from pre-operative imaging has the potential to reduce procedure times and improve patient outcomes in minimally invasive peripheral lung procedures, where breathing motion, small airways, and anatomical variation create a challenging environment for planned pathway navigation. Extraction of the rigid c-arm pose relative to preoperative images is a crucial prerequisite; however, accurate 2D-3D fluoroscopy-CT soft tissue registration in the presence of natural deformable patient motion remains challenging. We propose to train a patient-specific neural network on synthetic fluoroscopy derived from the patient’s pre-operative CT, augmented by a generalized breathing motion model, to predict c-arm pose. Our model includes an image supervision path that infers the x-ray projection geometry, providing training stability across patients. We train our model on synthetic fluoroscopy generated from preclinical swine CT and we evaluate on synthetic and real fluoroscopy.
Total selenium and selenium species in irrigation drain inflows to the Salton Sea, California, October 2007 and January 2008 (2008)

This report presents the results for two sampling periods (October 2007 and January 2008) during a 4-year monitoring program to characterize selenium concentrations in selected irrigation drains flowing into the Salton Sea, California. Total selenium, selenium species (selenite, selenate, organoselenium), and total suspended solids were determined in water samples, and total selenium was determined in sediment, detritus, and biota that included algae, plankton, midge larvae (family, Chironomidae), and two fish species-western mosquitofish (Gambusia affinis) and sailfin molly (Poecilia latipinna). In addition, sediments were analyzed for percent total organic carbon and particle size. Mean total selenium concentrations in water for both sampling periods ranged from 0.97 to 64.5 micrograms per liter, predominately as selenate, which is typical of waters where selenium is leached out of selenium-containing marine shales and associated soils under alkaline and oxidizing conditions. Total selenium concentrations (micrograms per gram dry weight) ranged as follows: algae, 0.95 to 5.99; plankton, 0.15 to 19.3; midges, 1.39 to 15.4; fish, 3.71 to 25.1; detritus, 0.85 to 21.7; sediment, 0.32 to 7.28.
Thermal decomposition of native oxide on Si(100) (1993)

We investigated the thermal decomposition of native oxide on Si(100) under ultrahigh vacuum using high-resolution x-ray photoelectron spectroscopy (XPS). The native oxide was formed by wet chemical treatment (HCl/H2O2/H2O), a widely employed procedure for preparing atomically clean surfaces. XPS measurements revealed that high temperature heating (≳700 °C) leads to a remarkable alteration in Si 2p and O 1s spectra. After heating to 700 °C, the Si3+ structure increases and the O 1s full-width-at-half-maximum decreases. After heating to 800 °C, the Si4+ and O 1s intensity decreases but the Si2+ intensity remains almost unchanged. We suggest that the formation of volatile SiO is related to the Si3+ structure produced by high temperature annealing.
Design and optimization of a dual-energy gas microstrip detector (2002)

The design principles and optimization procedures of a novel digital radiographic technique for dual-energy imaging based on gas microstrip hybrid defection principles are presented and analyzed. The detector consists of a solid state crystal coupled to a gas microstrip substrate. The proposed technology combines the high quantum detection efficiency of the solid state materials with the high gain and submicron resolution of the microstrip substrate. By simultaneously providing high spatial resolution and high contrast resolution it is expected that the dual-energy gas microstrip hybrid digital radiographic detector will have potential impact in medical diagnosis and treatment follow-up.
A novel method for RNA extraction from FFPE samples reveals significant differences in biomarker expression between orthotopic and subcutaneous pancreatic cancer patient-derived xenografts (2016)

Next-generation sequencing (NGS) can identify and validate new biomarkers of cancer onset, progression and therapy resistance. Substantial archives of formalin-fixed, paraffin-embedded (FFPE) cancer samples from patients represent a rich resource for linking molecular signatures to clinical data. However, performing NGS on FFPE samples is limited by poor RNA purification methods. To address this hurdle, we developed an improved methodology for extracting high-quality RNA from FFPE samples. By briefly integrating a newly-designed micro-homogenizing (mH) tool with commercially available FFPE RNA extraction protocols, RNA recovery is increased by approximately 3-fold while maintaining standard A260/A280 ratios and RNA quality index (RQI) values. Furthermore, we demonstrate that the mH-purified FFPE RNAs are longer and of higher integrity. Previous studies have suggested that pancreatic ductal adenocarcinoma (PDAC) gene expression signatures vary significantly under in vitro versus in vivo and in vivo subcutaneous versus orthotopic conditions. By using our improved mH-based method, we were able to preserve established expression patterns of KRas-dependency genes within these three unique microenvironments. Finally, expression analysis of novel biomarkers in KRas mutant PDAC samples revealed that PEAK1 decreases and MST1R increases by over 100-fold in orthotopic versus subcutaneous microenvironments. Interestingly, however, only PEAK1 levels remain elevated in orthotopically grown KRas wild-type PDAC cells. These results demonstrate the critical nature of the orthotopic tumor microenvironment when evaluating the clinical relevance of new biomarkers in cells or patient-derived samples. Furthermore, this new mH-based FFPE RNA extraction method has the potential to enhance and expand future FFPE-RNA-NGS cancer biomarker studies.