gebhart/patrepeval huggingface dataset:
&lt;i&gt;Brucella melitensis&lt;/i&gt; Differs from &lt;i&gt;B. suis&lt;/i&gt; in Growth and Urease Activity &lt;i&gt;In-Vitro&lt;/i&gt;, and Infectivity in Fisher-344 Rats &lt;i&gt;In-Vivo&lt;/i&gt; (2013)

Importance of urease activity on pathogenic differences among Brucella species was evaluated. In cell-free extracts, the B. suis urease showed 12 times greater specific activity than the B. melitensis urease. When Fisher-344 rats were inoculated intraperitoneally (IP), at 1 week post-inoculation (PI), B. melitensis wild type 16 M was recovered from spleens and livers in greater numbers than B. suis wild type 1330. At 8 weeks PI, spleens were clear of B. melitensis, whereas B. suis remained. The wild type and the urease deficient strains of B. suis did not differ from each other in terms of recovery from spleen or liver. Our observations suggest that B. melitensis induces greater acute infectivity in Fisher-344 rats, whereas B. suis causes chronic infectivity; and urease activity has no influence on Brucella infection using an IP route.
Experimental Elucidation of the Mechanism for Persistent Luminescence in SrAl2O4:Eu2+ and SrAl2O4:Eu2+,Dy3+ (2006)

Abstract not Available.
Feature-based subdivision surface fitting (2007)

Obtaining optimal and succinct representations for 3D models, usually defined as redundant dense polygonal meshes, is particularly of interest for many applications: animation, compression, recognition or understanding. Subdivision surfaces combine a lot of properties particularly relevant for this task: this model is very compact, can represent an arbitrary topology, authorizes a local control while being intrinsically multi-resolution. For these reasons, subdivision surfaces are increasingly popular in computer graphics and have been integrated to the MPEG4 standard. In this context, approximating a dense verbose polygonal mesh with this model becomes even more relevant.
Supplementary Figures from Haploinsufficiency of an RB–E2F1–Condensin II Complex Leads to Aberrant Replication and Aneuploidy (2023)

&lt;p&gt;PDF file 3766K, Analysis of gammaH2AX distribution, chromosomal instability phenotypes in heterozygous cells, and verification of genotypes in human cells&lt;/p&gt;
von Willebrand disease and pregnancy (2000)

von Willebrand Disease (vWD) affects approximately 1% of Americans and as many as 25% of women referred for evaluation of menorrhagia. We briefly review the history of vWD, its molecular defects, and diagnostic criteria for each subtype of disease. We also address obstetric management of the patient with vWD. While there is a significant increased risk for postpartum hemorrhage, patients with vWD should not be discouraged to undertake pregnancy. J. Matern.-Fetal Med. 2000;9:257–266. © 2000 Wiley-Liss, Inc.
P‐116: Thin Crystal Films (TCF) for LCD Contrast Enhancement (2003)

Abstract The paper describes applications of Optiva thin‐crystal film (TCF) coatings to enhance the contrast and viewing angle performance of many types of LCDs. These new nano‐film polarizers are based on supramolecular lyotropic liquid crystalline materials that can be deposited (printed) on virtually any substrate. The coating dries, crystallizes and exhibits the property of an E‐type polarizer, because it transmits the extraordinary wave of light. The additional thin (∼320nm) TCF coating on the front O‐polarizer of TN LCD shows the following performance changes with respect to the baseline configuration without TCF: considerable increase in contrast ratio out to about 30° and a small drop in luminance that becomes more substantial at large angles.
Strategic Plan for Lung Vascular Research: An NHLBI-ORDR Workshop Report (2010)

The Division of Lung Diseases of the National Heart, Lung, and Blood Institute, with the Office of Rare Diseases Research, held a workshop to identify priority areas and strategic goals to enhance and accelerate research that will result in improved understanding of the lung vasculature, translational research needs, and ultimately the care of patients with pulmonary vascular diseases. Multidisciplinary experts with diverse experience in laboratory, translational, and clinical studies identified seven priority areas and discussed limitations in our current knowledge, technologies, and approaches. The focus for future research efforts include the following: (1) better characterizing vascular genotype-phenotype relationships and incorporating systems biology approaches when appropriate; (2) advancing our understanding of pulmonary vascular metabolic regulatory signaling in health and disease; (3) expanding our knowledge of the biologic relationships between the lung circulation and circulating elements, systemic vascular function, and right heart function and disease; (4) improving translational research for identifying disease-modifying therapies for the pulmonary hypertensive diseases; (5) establishing an appropriate and effective platform for advancing translational findings into clinical studies testing; and (6) developing the specific technologies and tools that will be enabling for these goals, such as question-guided imaging techniques and lung vascular investigator training programs. Recommendations from this workshop will be used within the Lung Vascular Biology and Disease Extramural Research Program for planning and strategic implementation purposes.
Impact of humidity on the electrical performance of amorphous oxide semiconductor thin‐film transistors (2013)

Abstract An indium–gallium–zinc oxide or a zinc–tin oxide thin‐film transistor (TFT) fabricated when the relative humidity in the laboratory is less than 50% is found to exhibit good electrical performance, with an abrupt, distortion‐free transfer curve and a turn‐on voltage close to 0 V. In contrast, when such an amorphous oxide semiconductor (AOS) TFT is fabricated at a relative humidity greater than 50%, its “as‐fabricated” electrical performance is very poor, typically characterized by a large amount of hysteresis, a strongly negative turn‐on voltage, and a kink‐like distortion in the subthreshold region of its transfer curve. However, the electrical performance of such a poor‐quality TFT is observed to improve over time, if it is simply stored in the dark at room temperature without being subjected to electrical stress. This recovery usually requires weeks (months) for an unpassivated (passivated) AOS TFT. Recovery is tentatively ascribed to the gradual removal of moisture from the AOS TFT channel layer.
FIELD EVALUATION OF STEEL FIBER REINFORCED CONCRETE OVERLAY WITH VARIOUS BONDING MECHANISMS (1989)

An experimental rehabilitation project was conducted on the Transcanadian Highway where old concrete pavement was recovered with a thin, steel fiber reinforced concrete overlay. In this project, 18 different construction conditions were investigated. The surface of the old pavement was either sandblasted or scarified. Three different types of steel fibers were used, and all the overlay was bonded with a thin cement grout. In addition, two lanes were repaired with some mechanical bonding provided by 37.5-mm (1.5-in.) steel nails. The most significant results obtained during the construction period as well as all data recorded over the succeeding two winters are reported and analyzed in this paper.
Selection of near-minimum time geometric paths for robotic manipulators (1986)

A number of trajectory planning algorithms exist for calculating the joint positions, velocities, and torques which will drive a robotic manipulator along a given geometric path in minimum time. However, the time depends upon the geometric path, so the traversal time of the path should be considered again for geometric planning. There are algorithms available for finding minimum distance paths, but even when obstacle avoidance is not an issue, minimum (Cartesian) distance is not necessarily equivalent to minimum time. In this paper, we have derived a lower bound on the time required to move a manipulator from one point to another, and determined the form of the path which minimizes this lower bound. As numerical examples, we have applied the path solution to the first three joints of the Bendix PACS arm and the Stanford arm. These examples do indeed demonstrate that the derived approximate solutions usually require less time than Cartesian straight-line (minimum-distance) paths and joint-interpolated paths.
ChemInform Abstract: Cascade Palladium Catalysis: A Predictable and Selectable Regiocontrolled Synthesis of N‐Arylbenzimidazoles. (2014)

Abstract A novel Pd‐catalyzed regioselective approach to N‐alkylbenzimidazoles is developed.
Technologies for large scale InP-based optoelectronic integrated circuits (1997)

We discuss approaches to achieving large scale InP-based optoelectronic integrated circuits (OEICs) and photonic integrated circuits (PICs). During the past several years, significant advances have been made in improving materials and device quality of InP-based materials such as InGaAs(P) for use in long wavelength communications systems and networks. Hence, we are currently on the threshold of realizing large scale (greater than 500 device) OEICs from which will emerge a new generation of optoelectronic systems and applications, in analogy to what was achieved in the 1970s with the advent of Si-based electronic LSI. What remains to be demonstrated to bring this vision to practical reality is the demonstration of 'platform' integration technologies where devices and circuits custom-designed for a wide range of applications can be realized using a common (and simple) epitaxial materials structure and fabrication process. For the last several years, we have developed such platform technologies, with our latest success being the demonstration of a 16 by 16 InGaAs/InP imaging array consisting of 272 field effect transistors and 256 p-i-n detectors. Other devices which have been demonstrated using this technology have been very high sensitivity switched photodiode receivers, and coherent optical receivers. The transmitter technology consists of a modified twin waveguide structure which allows for fabrication tolerant fabrication of photonic integrated circuits employing any combination of lasers, optical amplifiers, modulators and waveguides. The extremely high yield and simplicity of processing of such InP-based LSI circuits suggests that the scale of optoelectronic integration in this important materials system has reached a new, and highly useful level of sophistication.
Collagen-Based Drug Delivery Devices (2023)

The recent medical literature contains a number of references to several promising applications for collagen-based drug delivery devices. Since most current promising drug delivery applications of collagen involve either collagen-based implants or ocular inserts, this survey is concerned primarily with two types of applications. Thus, it was concluded that the crosslinked collagen implant is capable of providing high and prolonged concentrations of gentamicin, and possibly other antibiotics, at the site of implantation. Although Firsov et al. consistently indicated that their collagen implants were biodegradable, no direct histological, weight loss, or radiotracer data demonstrating implant biodegradability or rate of biodegradation were presented. All pellets evaluated were implanted subcutaneously in male Long-Evans rats. Heparin-containing implants had a more distinct fibrillar organization than implants free of heparin, and this may have provided a better environment for cell invasion.
Retroperitoneal Fibrosis in Association with Urothelial Tumor (1984)

One of the less common associations of retroperitoneal fibrosis is malignancy. Although there have been many reports on tumors associated with retroperitoneal fibrosis urothelial tumors are rare. We report a case of retroperitoneal fibrosis and urothelial malignancy of the renal pelvis.
Recent Advances in Ultra Low Erosion Cu CMP Process Development (2010)

Abstract not Available.
Shortest Path Versus Multihub Routing in Networks With Uncertain Demand (2014)

We study a class of robust network design problems motivated by the need to scale core networks to meet increasingly dynamic capacity demands. Past work has focused on one of two models. First, design the network for the known point-to-point peak demands. Second, design the network to support all hose matrices (all matrices not exceeding marginal bounds at the nodes). Both models may be too conservative if additional information on traffic patterns is available. We introduce a capped hose model to explore a range of traffic scenarios, which includes the above two as special cases. It is known that optimal network designs for the hose model are always determined by single-hub routing, and for the fixed-demand model are based on shortest-path routing. We demonstrate that a wider variety of routing templates is required to address the broader spectrum of capped hose matrices. We propose the use of hierarchical multihub routing templates, a generalization of hub and tree routing. Our empirical analysis is based on a heuristic for the resulting robust network design problem. These lead to two important findings: 1) designs based on multihub routing are often preferable to both hub and shortest path; 2) it may be possible for a carrier to sample their traffic in order to determine which type of routing is most cost-effective for their network.
A Highly Reliable and Cost Effective 16nm Planar NAND Cell Technology (2015)

A 2D 16nm planar NAND cell technology is described with good cell to cell interference and reliability that can be used in a wide variety of applications. This second generation planar cell uses a high-K dielectric stack and a thin poly floating gate to maintain the needed gate coupling ratio and reduce adjacent cell interference. The technology includes select gates with the same planar structure as the cell. This select gate architecture simplifies the manufacturing of this NAND technology.
Laser Flash Photolysis and Computational Study of Singlet Phenylnitrene (1999)

Laser flash photolysis (LFP, Nd:YAG laser, 35 ps, 266 nm, 10 mJ) of phenyl azide (PA) releases open-shell singlet phenylnitrene (1PN). 1PN has a sharp absorption band at 350 nm and a very weak absorption band at 540 nm. These bands are assigned as nz−ny and a mixture of 52% π−nx and 28% nx−π* transitions, respectively, on the basis of CASSCF and CASPT2 calculations. A CASPT2 calculation of the spectrum of triplet phenylnitrene (3PN) is in very good agreement with the experimental spectrum. A sharp absorption band of 3PN at 308 nm and a broad, structured band at 370 nm are assigned as nz−ny and π−π transitions on the basis of CASSCF and CASPT2 calculations. The low intensity, long wavelength band of 3PN tailing to 500 nm is assigned as a mixture of π−nx, nx−π* transitions. The decay of 1PN in pentane was measured as a function of temperature to obtain observed rate constants of disappearance, kobs. The rate constant kobs is equal to kR + kISC, where kR is the absolute rate constant of rearrangement of 1PN to benzazirine and kISC is the absolute rate constant of intersystem crossing to the lower energy triplet state (3PN). When it is assumed that kISC is independent of temperature, kobs can be dissected, and absolute values of kR and kISC can be deduced. For 1PN, kISC = 3.2 ± 0.3 × 106 s-1 and the Arrhenius parameters for kR are found to be Ea = 5.6 ± 0.3 kcal mol-1 and A = 1013.1±0.3 s-1.
Tessellated granular metamaterials with tunable elastic moduli (2023)

Most granular packings possess shear moduli ($G$) that increase with the applied external pressure, and bulk moduli ($B$) that increase or remain constant with pressure. This paper presents "tessellated" granular metamaterials for which both $G$ and the ratio $G/B$ decrease with increasing pressure. The granular metamaterials are made from flexible tessellations forming a ring of closed cells, each containing a small number of solid particles. For under-constrained tessellations, the dominant contributions to $G$ and $B$ are the particle-particle and particle-cell interactions. With specific particle configurations in the cells, we limit the number of possible particle rearrangements to achieve decreasing $G$ as we increase the pressure difference between the inside and outside of the tessellation, leading to $G/B \ll 1$ at large pressures. We further study tessellated granular metamaterials with cells containing a single particle and many particles to determine the variables that control the mechanical response of particle-filled tessellations as a function of pressure.
Interaction of Cartilage Oligomeric Matrix Protein/Thrombospondin 5 with Aggrecan (2007)

Cartilage oligomeric matrix protein/thrombospondin 5 (COMP/TSP5) is a major component of the extracellular matrix (ECM) of the musculoskeletal system. Its importance is underscored by its association with several growth disorders. In this report, we investigated its interaction with aggrecan, a major component of cartilage ECM. We also tested a COMP/TSP5 mutant, designated MUT3 that accounts for 30% of human pseudoachondroplasia cases, to determine if the mutation affects function. Using a solid-phase binding assay, we have shown that COMP/TSP5 can bind aggrecan. This binding was decreased with MUT3, or when COMP/TSP5 was treated with EDTA, indicating the presence of a conformation-dependent aggrecan binding site. Soluble glycosaminoglycans (GAGs) partially inhibited binding, suggesting that the interaction was mediated in part through aggrecan GAG side chains. Using affinity co-electrophoresis, we showed that COMP/TSP5, in its calcium-replete conformation, bound to heparin, chondroitin sulfates, and heparan sulfate; this binding was reduced with EDTA treatment of COMP/TSP5. MUT3 showed weaker binding than calcium-repleted COMP/TSP5. Using recombinant COMP/TSP5 fragments, we found that the "signature domain" could bind to aggrecan, suggesting that this domain can mediate the interaction of COMP/TSP5 and aggrecan. In summary, our data indicate that COMP/TSP5 is an aggrecan-binding protein, and this interaction is regulated by the calcium-sensitive conformation of COMP/TSP5; interaction of COMP with aggrecan can be mediated through the GAG side chains on aggrecan and the "signature domain" of COMP/TSP5. Our results suggest that COMP/TSP5 may function to support matrix interactions in cartilage ECM.
Scientific data repositories (2003)

Managing scientific data warehouses requires constant adaptations to cope with changes in processing algorithms, computing environments, database schemas, and usage patterns. We have faced this challenge in the RHESSI Experimental Data Center (HEDC), a datacenter for the RHESSI NASA spacecraft. In this paper we describe our experience in developing HEDC and discuss in detail the design choices made. To successfully accommodate typical adaptations encountered in scientific data management systems, HEDC (i) clearly separates generic from domain specific code in all tiers, (ii) uses a file system for the actual data in combination with a DBMS to manage the corresponding meta data, and (iii) revolves around a middle tier designed to scale if more browsing or processing power is required. These design choices are valuable contributions as they address common concerns in a wide range of scientific data management systems.
Surface Functionalization of Poly(ethylene) with Succinic Anhydride:  Preparation, Modification, and Characterization (1997)

Succinic anhydride groups have been introduced on the surface of and in bulk poly(ethylene) film by a mild photochemical process. These groups on the poly(ethylene) film undergo facile transformation to various functional groups such as acids, esters, or amides by reaction with water, amine compounds, or PEG, etc. The surface functionality has been quantitatively estimated by using gravimetry, ATR-FTIR, XPS, and UV−visible spectroscopy. Surface hydrophilicity was characterized by contact angle goniometry. The poly(ethylene) bound to the azobenzene group, exhibiting interesting responses to external stimuli such as photoinduced and thermally induced E:Z isomerization.
Magnetic Properties of Fe-49Co-2V Alloy and Pure Fe at Room and Elevated Temperatures (2018)

The National Aeronautics and Space Administration (NASA) has a need for soft magnetic materials for fission power and ion propulsion systems. In this work the magnetic properties of the soft magnetic materials Hiperco 50 (Fe-49wt%Cr-2V) and CMI-C (commercially pure magnetic iron) were examined at various temperatures up to 600 C. Toroidal Hiperco 50 samples were made from stacks of 0.35 mm thick sheet, toroidal CMI-C specimens were machined out of solid bar stock, and both were heat treated prior to testing. The magnetic properties of a Hiperco 50 sample were measured at various temperatures up to 600 C and then again after returning to room temperature; the magnetic properties of CMI-C were tested at temperatures up to 400 C. For Hiperco 50 coercivity decreased as temperature increased, and remained low upon returning to room temperature; maximum permeability improved (increased) with increasing temperature and was dramatically improved upon returning to room temperature; remanence was not significantly affected by temperature; flux density at H = 0.1 kA/m increased slightly with increasing temperature, and was about 20% higher upon returning to room temperature; flux density at H = 0.5 kA/m was insensitive to temperature. It appears that the properties of Hiperco 50 improved with increasing temperature due to grain growth. There was no significant magnetic property difference between annealed and aged CMI-C iron material; permeability tended to decrease with increasing temperature; the approximate decline in the permeability at 400 C compared to room temperature was 30%; saturation flux density, B(sub S), was approximately equal for all temperatures below 400 C; B(sub S) was lower at 400 C.
Automated Tool Handling for the Trauma Pod Surgical Robot (2007)

In order to enable robotic surgery without human assistance, a means must be developed to change tools. As part of the larger Trauma Pod Project, we developed the Tool Rack Subsystem - an automated tool rack capable of holding, accepting, and dispensing up to 14 tools for the da Vinci surgical robot. Borrowing some techniques from industrial automation, we developed a robust system capable of presenting any stored tool in 700ms or less. Tools are positively retained in a sterilizable carousel in a compliant manner designed to accomodate misalignment during tool exchange. RFID equipment is integrated into the system and the tools so that tools can be inventoried and presented by function or serial number instead of rack position. The resulting device has completed testing and integration into the Trauma Pod system and met all its design requirements.