gebhart/patrepeval huggingface dataset:
Chimeric AGAMOUS repressor induces serrated petal phenotype in Torenia fournieri similar to that induced by cytokinin application (2008)

The homeotic protein AGAMOUS (AG) terminates the floral meristem and promotes the development of stamens and carpels in Arabidopsis. Disruption of its function or expression of the chimeric AG repressor (AGSRDX) results in redundant petals, known as a double flower phenotype. To investigate whether this morphological change in Arabidopsis is applicable to ornamental flowers to increase their horticultural value, we introduced AGSRDX into torenia (Torenia fournieri Lind.) plants. Transgenic torenia plants expressing AGSRDX showed no redundancy in petal number, although they exhibited serration in petal margins, anthocyanin accumulation and morphological change in the stigma surface, and formation of extra vascular bundles in petals and styles. Anatomical observation of petals and styles revealed that these phenotypes are highly similar to those of forchlorfenuron (CPPU)-treated torenia plants especially in the derangement of vascular bundles. Phenotypes similar to AGSRDX transgenic torenia plants were also observed when the chimeric repressors for torenia C-function genes TfFAR or TfPLE1, homologs of Antirrhinum FARINELLI and PLENA respectively, were expressed. These results suggest that the morphological changes in AGSRDX transgenic torenia plants are induced by the disruption of C-function. These novel phenotypes might be caused by the modification of cytokinin-dependent regulation in vascular bundle formation and ectopic expression of the chimeric repressors in all whorls by the cauliflower mosaic virus (CaMV) 35S promoter.
Omnidirectional reflector using nanoporous SiO_2 as a low-refractive-index material (2005)

Triple-layer omnidirectional reflectors (ODRs) consisting of a semiconductor, a quarter-wavelength transparent dielectric layer, and a metal have high reflectivities for all angles of incidence. Internal ODRs (ambient material's refractive index n >> 1.0) are demonstrated that incorporate nanoporous SiO2, a low-refractive-index material (n = 1.23), as well as dense SiO2 (n = 1.46). GaP and Ag serve as the semiconductor and the metal layer, respectively. Reflectivity measurements, including angular dependence, are presented. Calculated angle-integrated TE and TM reflectivities for ODRs employing nanoporous SiO2 are R(int)/TE = 99.9% and R(int)/TM = 98.9%, respectively, indicating the high potential of the ODRs for low-loss waveguide structures.
A Fully Integrated 27-dBm Dual-Band All-Digital Polar Transmitter Supporting 160 MHz for Wi-Fi 6 Applications (2020)

This work presents a dual-band polar digital transmitter (P-DTX) based on a digitally controlled two-point edge interpolation digital-to-time converter, which is capable of supporting Wi-Fi 6 applications. The proposed P-DTX is fabricated in a standard 28-nm CMOS process. The 2.5/5GHz digital power amplifiers (DPAs) reach a maximum power (P <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">MAX</sub> )/power efficiency (PE) of 27 dBm/53% and 27dBm/37%, respectively. The transmitter meets an error vector magnitude (EVM)/DPA PE/total TX power dissipation of -30.5 dB/33%/532 mW for the low band and -29 dB/26%/718 mW for the high band at 6-dB backoff (dBBO) from PMAX. An EVM as low as -40 dB is achieved using digital pre-distortion at 7-8 dBBO, for 20-160-MHz signal bandwidths, thus demonstrating MCS11 1024-QAM OFDM Wi-Fi 6 operation.
Utility of Translocator Protein (18 kDa) as a Molecular Imaging Biomarker to Monitor the Progression of Liver Fibrosis (2015)

Hepatic fibrosis is the wound healing response to chronic hepatic injury caused by various factors. In this study, we aimed to evaluate the utility of translocator protein (18 kDa) (TSPO) as a molecular imaging biomarker for monitoring the progression of hepatic fibrosis to cirrhosis. Model rats were induced by carbon tetrachloride (CCl4), and liver fibrosis was assessed. Positron emission tomography (PET) with N-benzyl-N-methyl-2-[7,8-dihydro-7-(2-[(18)F]fluoroethyl)-8-oxo-2-phenyl-9H-purin-9-yl]-acetamide ([(18)F]FEDAC), a radioprobe specific for TSPO, was used for noninvasive visualisation in vivo. PET scanning, immunohistochemical staining, ex vivo autoradiography, and quantitative reverse-transcription polymerase chain reaction were performed to elucidate the relationships among radioactivity uptake, TSPO levels, and cellular sources enriching TSPO expression in damaged livers. PET showed that uptake of radioactivity in livers increased significantly after 2, 4, 6, and 8 weeks of CCl4 treatment. Immunohistochemistry demonstrated that TSPO was mainly expressed in macrophages and hepatic stellate cells (HSCs). TSPO-expressing macrophages and HSCs increased with the progression of liver fibrosis. Interestingly, the distribution of radioactivity from [(18)F]FEDAC was well correlated with TSPO expression, and TSPO mRNA levels increased with the severity of liver damage. TSPO was a useful molecular imaging biomarker and could be used to track the progression of hepatic fibrosis to cirrhosis with PET.
Magnetic properties of epitaxial CrN films (2006)

The authors have investigated the structural and magnetic properties of CrN films grown on MgO(001) and sapphire(0001) by rf-plasma-assisted molecular beam epitaxy. CrN∕MgO(001) exhibits a better epitaxial quality than CrN/sapphire(0001). The CrN∕MgO film shows clear paramagnetic behavior at low temperatures, whereas CrN/sapphire exhibits a ferromagneticlike response with an order temperature above room temperature which resembles the magnetic behavior found in Cr-doped dilute magnetic semiconductors. Keeping in mind that bulk CrN exhibits antiferromagnetic behavior, the dramatically different magnetic behaviors found in epitaxial CrN films grown on MgO and sapphire demonstrate the importance of epitaxial constraints in determining their magnetic properties.
Supplementary figures from ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism (2023)

&lt;p&gt;Supplementary Figure 1. ZIP4 is correlated with EMT markers in pancreatic cancer tissue of KPC mice. Supplementary Figure 2. Knocking down ZIP4 upregulated ZO-1 and claudin-1 expression in pancreatic cancer. Supplementary Figure 3. Knocking down ZIP4 regulated mRNA of EMT markers in pancreatic cancer cell lines. Supplementary Figure 4. ZIP4 repressed ZO-1 and claudin-1 is independent with CREB. Supplementary Figure 5. Knocking down efficiency of ZO-1 and claudin-1 in AsPC-shZIP4 cells.&lt;/p&gt;
Green-Marl (2012)

The increasing importance of graph-data based applications is fueling the need for highly efficient and parallel implementations of graph analysis software. In this paper we describe Green-Marl, a domain-specific language (DSL) whose high level language constructs allow developers to describe their graph analysis algorithms intuitively, but expose the data-level parallelism inherent in the algorithms. We also present our Green-Marl compiler which translates high-level algorithmic description written in Green-Marl into an efficient C++ implementation by exploiting this exposed data-level parallelism. Furthermore, our Green-Marl compiler applies a set of optimizations that take advantage of the high-level semantic knowledge encoded in the Green-Marl DSL. We demonstrate that graph analysis algorithms can be written very intuitively with Green-Marl through some examples, and our experimental results show that the compiler-generated implementation out of such descriptions performs as well as or better than highly-tuned hand-coded implementations.
Change in Peripheral Refraction over Time in Singapore Chinese Children (2011)

PURPOSE. Relative peripheral hyperopia has been associated with central myopia. This study was conducted to determine whether baseline relative peripheral hyperopia is associated with an increased risk of developing myopia or myopia progression in young Singapore Chinese children. METHODS. One hundred eighty-seven children who participated in the Peripheral Refraction in Preschool Children (PREP) Study at baseline underwent a follow-up examination. Autorefraction was performed at five eccentricities with an infrared autorefractor after cycloplegia: central axis and 15° and 30° eccentricities in the nasal and temporal visual fields. The primary outcomes were development of myopia among children who were nonmyopic at baseline, and myopia progression in those who were myopic at baseline. RESULTS. The mean age of the children at baseline was 7.2 ± 3.0 years, and the mean duration of follow-up was 1.26 years. At baseline, 96 children were myopic (mean central spherical equivalent [SE] -2.75 ± 1.72 D) and 91 were nonmyopic (mean central SE 0.76 ± 0.81 D). Baseline relative peripheral hyperopia was not associated with a greater likelihood of becoming myopic or myopia progression. At follow-up, children who remained nonmyopic (n = 24) retained relative peripheral myopia at all eccentricities, whereas those who became myopic (n = 67) developed relative peripheral hyperopia at the nasal (+0.44 ± 0.72 D) and temporal 30° (+0.13 ± 0.74 D). The mean change in central SE was -1.51 ± 0.63 D/y for children who developed myopia, -0.82 ± 0.76 D/y for children who were myopic at baseline, and -1.05 ± 0.80 D/y for all children. CONCLUSIONS. Baseline peripheral refraction did not predict the subsequent onset of myopia or influence the progression of myopia.
Nonlinear Regularization for Per Voxel Estimation of Magnetic Susceptibility Distributions From MRI Field Maps (2009)

Magnetic susceptibility is an important physical property of tissues, and can be used as a contrast mechanism in magnetic resonance imaging (MRI). Recently, targeting contrast agents by conjugation with signaling molecules and labeling stem cells with contrast agents have become feasible. These contrast agents are strongly paramagnetic, and the ability to quantify magnetic susceptibility could allow accurate measurement of signaling and cell localization. Presented here is a technique to estimate arbitrary magnetic susceptibility distributions by solving an ill-posed inversion problem from field maps obtained in an MRI scanner. Two regularization strategies are considered: conventional Tikhonov regularization and a sparsity promoting nonlinear regularization using the l(1) norm. Proof of concept is demonstrated using numerical simulations, phantoms, and in a stroke model in a rat. Initial experience indicates that the nonlinear regularization better suppresses noise and streaking artifacts common in susceptibility estimation.
Multi-Mode Rectifier-Based Dual-Input LLC Converter for Wide Voltage PV Applications (2022)

This paper proposes a dual-input LLC resonant converter with a multi-mode rectifier that interfacing wide-input and high dc-bus voltage ports for photovoltaic (PV) applications. The topology interfaces two PV panels as power sources by utilizing a dual half-bridge LLC circuit and multi-mode rectifier. In this topology, both PV sources use the same resonant tank for transferring energy to the load. The wide range of the switching frequency change for tracking maximum power point (MPP) of PVs sources reduces the efficiency of the dual-input LLC converter. This paper proposes a multi-mode rectifier on the secondary side of the dual-input LLC to limit the switching frequency change for tracking the MPP of PVs. By configuring a voltage-tripler, voltage-quadrupler, or voltage-fifthfolder rectifier and utilizing frequency modulation, a narrow frequency range and moderate transformer size are realized with an extended output voltage and high efficiency. In addition, soft-switching for primary MOSFETs and rectifier diodes is desired. A dual-input LLC resonant converter with a multi-mode rectifier for 300 W was built and tested. The related measured waveforms are demonstrated to prove the correctness and feasibility of the theoretical analysis.
MAGNETIC RESONANCE IMAGING OF THE BRAIN IN SYSTEMIC LUPUS ERYTHEMATOSUS (1995)

Magnetic resonance imaging (MRI) of the brain is a sensitive method to detect parenchymal tissue lesions. Its value in the diagnosis of central nervous system (CNS) lupus is disputed. To address this question, we have conducted an open and prospective study in a population of 44 SLE patients. We investigated 24 patients (mean age 33 +/- 13 yr) with past or active CNS lupus (group A) that included organic brain syndrome (12), migraine (8), focal neurological signs (7), seizures (2), myelopathy (1) and narcolepsy-cataplexy (1), and 20 patients (mean age 32 +/- 12 yr) without CNS lupus (group B). Health controls comprising nine females and one male aged 31 +/- 9 yr were also studied for comparison (group C). MRI was performed using sagittal T1-weighted images, axial and coronal spin density, and T2-weighted images. All scans were read blindly. Thirteen patients in group A and 10 in group B had well-identified lesions on sequences with long repetition time. Lesions were mostly multiple, small, punctate areas of increased signal at periventricular or subcortical white matter of both cerebral hemispheres. The number and location of lesions were not significantly different in both groups. None of the group C patients had MRI lesions. The presence of lesions was significantly associated with age at study and disease duration, but not with the presence of CNS lupus. In summary, MRI abnormalities are detected in neurologically asymptomatic SLE patients. Whether this represents subclinical brain involvement remains unknown.
Rh-Catalyzed C-H Activation Route to Bicyclic Imidazoles (2007)

A Rh-catalyzed synthesis of aryl-substituted bicyclic imidazoles via C-H activation is described. Using imidazoles with N-chiral appendages, this intramolecular alkylation proceeds smoothly with high enantioinduction and moderate yields to afford the fused imidazoles which are difficult to make, especially with chiral centers at C-7 and C-8 positions. The methyl substitution at C-7 is significant for potent bioactivity.
Dynamic CT vs 0.5 T MR Imaging in the Detection of Surgically Proven Hepatic Metastases (1989)

Seventeen patients with 52 surgically proven hepatic metastases were studied preoperatively with dynamic CT and 0.5 T magnetic resonance (MR). Dynamic CT detected 38 metastases (73%), and the combination of short echo time (T1-weighted) and T2-weighted pulse sequences detected 46 lesions (88%). Magnetic resonance was also superior at assessing potential resectability. This study suggests that MR excels in detecting and anatomically localizing individual hepatic metastases.
ChemInform Abstract: Asymmetric Synthesis of Functionalized Pyrrolidines. Highly Diastereoselective Cyclization Mediated by Sulfide and Sulfoxide Ligands. (1992)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Synthesis of oxidation resistant lead nanoparticle films by modified pulsed laser ablation (2012)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Eunsung Shin, P. Terrence Murray, Guru Subramanyam, Hans K. Malik, Kenneth L. Schwartz; Synthesis of oxidation resistant lead nanoparticle films by modified pulsed laser ablation. AIP Conference Proceedings 30 July 2012; 1464 (1): 190–199. https://doi.org/10.1063/1.4739873 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Binding of aggregated human beta2-microglobulin to surface protein structure in group A, C, and G streptococci (1978)

A novel mammalian-microbial "short circuit" has been demonstrated between aggregated human beta2-microglobulin and group A, C, and G streptococci. Bacteria belonging to nine gram-positive and three gram-negative species were tested for binding of radiolabeled beta2-microglobulin. All 10 individual strains of group A streptococci showed a high degree of reactivity with aggregated human beta2-microglobulin. Among 27 group C and 28 group G streptococci, 9 and 6 strains, respectively, were highly reactive, whereas the remaining strains showed a lower, but definite level of beta2-microglobulin binding. Of 11 group B streptococci, 4 were slightly positive. All strains among the other eight species were completely negative. Simultaneous testing of A, C, and G streptococci for immunoglobulin binding showed a lack of correlation between type II and III Fc reactivity and beta2-microglobulin binding. There was no inhibition of uptake of aggregated beta2-microglobulin to reactive strains when excess amounts of human immunoglobulin were added. The beta2-microglobulin-binding surface structure was found to be markedly sensitive to trypsin digestion. The relative trypsin resistance of the immunoglobulin-binding protein in the digestion experiments further demonstrated the dissociation between these two reactivities.
A new, efficient structure for the short-time Fourier transform, with an application in code-division sonar imaging (1991)

Although most applications which use the short-time Fourier transform (STFT) temporally downsample the output, some applications exploit a dense temporal sampling of the STFT. One example, coded-division multiple-beam sonar, is discussed. Given a need for the densely sampled STFT, the complexity of the computation can be reduced from O(N log N) for the general short-time FFT structure to O(N) using the Goertzel algorithm. The authors introduce the pruned short-time FFT, a novel computational structure for efficiently computing the STFT with dense temporal sampling. The pruned FFT achieves the same computational savings as the Goertzel algorithm, but is unconditionally stable.< <ETX xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">&gt;</ETX>
Kinase M utations a nd I matinib R esponse i n P atients W ith Metastatic G astrointestinal S tromal T umor (2003)

Purpose: Most gastrointestinal stromal tumors (GISTs) express constitutively activated mutant isoforms of KIT or kinase platelet-derived growth factor receptor alpha (PDGFRA) that are potential therapeutic targets for imatinib mesylate. The relationship between mutations in these kinases and clinical response to imatinib was examined in a group of patients with advanced GIST. Patients and Methods: GISTs from 127 patients enrolled onto a phase II clinical study of imatinib were examined for mutations of KIT or PDGFRA. Mutation types were correlated with clinical outcome. Results: Activating mutations of KIT or PDGFRA were found in 112 (88.2%) and six (4.7%) GISTs, respectively. Most KIT mutations involved exon 9 (n 23) or exon 11 (n 85). All KIT mutant isoforms, but only a subset of PDGFRA mutant isoforms, were sensitive to imatinib, in vitro. In patients with GISTs harboring exon 11 KIT mutations, the partial response rate (PR) was 83.5%, whereas patients with tumors containing an exon 9 KIT mutation or no detectable mutation of KIT or PDGFRA had PR rates of 47.8% (P .0006) and 0.0% (P < .0001), respectively. Patients whose tumors contained exon 11 KIT mutations had a longer event-free and overall survival than those whose tumors expressed either exon 9 KIT mutations or had no detectable kinase mutation. Conclusion: Activating mutations of KIT or PDGFRA are found in the vast majority of GISTs, and the mutational status of these oncoproteins is predictive of clinical response to imatinib. PDGFRA mutations can explain response and sensitivity to imatinib in some GISTs lacking KIT mutations. J Clin Oncol 21:4342-4349. © 2003 by American Society of Clinical Oncology.
Primary functioning hepatic paraganglioma mimicking hepatocellular carcinoma (2018)

By means of reporting this case and reviewing 11 reported cases, we conclude that the incidence of HPGLs is extremely low and the clinical and radiological characteristics of HPGLs are nonspecific; thus, it is hard to diagnose HPGLs correctly. Surgical resection is curative therapy for HPGLs, whereas the removing of HPGLs may cause the releasing of catecholamine, and then lead to hypertension crisis and arrhythmia. Thus, antihypertensive therapy is necessary during the operation. Follow-ups after the operation are important for HPGL patients, for pathological examinations are not sufficient to differ malignant HPGLs from benign ones, and follow-ups are helpful for HPGL patients to find the recurrent foci or metastases timely.
Estimation of gramian-based interaction measures for weakly nonlinear systems (2015)

A critical step in the control design of industrial processes is the Control Configuration Selection (CCS), where each actuator is grouped with a set of measurements to be used in the computation of its control action. Tools for CCS include gramian-based Interaction Measures (IMs), initially defined for linear systems. Since a trending research topic is the derivation of IMs for nonlinear systems, a decision of the designer is therefore the approach to the problem in the linear or nonlinear framework. For this end, a method is discussed that determines the degree of nonlinearity of a system based on a specially tailored experiment, and thus enables the selection of the correct framework for the analysis. The novelty is in the estimation of two gramian-based IMs with confidence bounds from the tailored experiment which is applicable if the process is revealed to be weakly nonlinear.
Compressive Cfar Radar Processing (2013)

Publication in the conference proceedings of SampTA, Bremen, Germany, 2013
An all-polymer thin-film scanning optical filter for 3D-image displays (2003)

Built a transparent thin-film scanning optical filter, which can be attached to displays to show 3D-images. The scanning motion provides more quality images depending on the viewpoints. Water droplets are put in the filter as microlenses which is driven electrostatically. All the structure of the filter, including conductive elements, is made of transparent polymer films. The electrodes to drive the microlenses are conductive polymer Baytron P/sup /spl reg// patterned with a new technique using selectivity of hydrophobic and hydrophilic regions on the surface. Since the scanning filter consists of multi layers, new functions can be easily added by attaching another layer on top or bottom of the filter. In this paper, an LCD (liquid crystal display) was attached to the bottom as a light source layer.
Acoustic Characterisation of Phase Inversion in a Water-Oil System (2019)

Abstract The present paper is concerned with an experimental study of the acoustic signature of phase inversion in an oil-water mixture system. The system studied was used to correlate the process of phase inversion with the acoustic field generated during the two fluid mixing. The experimental results revealed that the relation between the acoustic fields produced by a water continuous dispersion and the phase inversion has a clear and different signature from an oil-continuous system using a batch mixing system. This dynamical characteristic of the phase inversion phenomenon could be of use in practical systems to detect phase inversion when it occurs based on the acoustic field measured in the subject process.