gebhart/patrepeval huggingface dataset:
Analysis of copper plasticity impact in TSV-middle and backside TSV-last fabrication processes (2015)

Copper plasticity effects in TSV middle and backside TSV last integration flows are analyzed using an advanced 3D TCAD simulator with model parameters calibrated to match experimental data. In this work, a low thermal budget TSV last integration flow is considered. In contrast to the TSV middle flow, the TSV last flow studied here exhibits insignificant TSV pumping, M1 metal thinning or M1 metal resistance increase. The difference in residual stress profiles in BEOL structure for TSV middle and TSV last processes indicates that the process sequence must be optimized in order to minimize the reliability risks. The mobility change in active silicon for the TSV last process is lower as compared to that for the TSV middle process at room temperature due to the lower temperature excursions during the TSV last integration. This study demonstrates that the TSV integration flow must be designed and selected carefully to meet specific performance and reliability requirements.
Supplementary Fig. S3 from <i>Salmonella</i>-Based Therapy Targeting Indoleamine 2,3-Dioxygenase Coupled with Enzymatic Depletion of Tumor Hyaluronan Induces Complete Regression of Aggressive Pancreatic Tumors (2023)

&lt;p&gt;Key replicate treatment groups (A) Replicate IVIS images of key treatment groups emphasizing reproducibility of treatment in KPC orthotopic model. Numbers above images represent days post-tumor implantation. (B) Quantitation of IVIS luciferase signal for individual mice in key groups represented in Fig. 1A and Supplementary Fig. S3A.&lt;/p&gt;
Time-resolved crossed-beam thermal lens measurement as a nonintrusive probe of flow velocity (1985)

A simple theory is generated for crossed-beam thermal lens and photothermal deflection in flowing sample streams. This theory is used to analyze time-resolved crossed-beam thermal lens data. The result of the regression analysis may be used as a good probe of flow velocity in the 0.2–30-mm/sec range in liquid streams. Faster flow velocity should be measurable in gas streams.
Quinaphos and Dihydro‐Quinaphos Phosphine–Phosphoramidite Ligands for Asymmetric Hydrogenation (2010)

New derivatives of the Quinaphos ligands and the related Dihydro-Quinaphos ligands based on the more flexible 1,2,3,4-tetrahydroquinoline backbone have been prepared and fully characterised. A general and straightforward separation protocol was devised, which allowed for the gram-scale isolation of the R(a),S(c) and S(a),R(c) diastereomers. These new phosphine-phosphoramidite ligands have been applied in the Rh-catalysed asymmetric hydrogenation of functionalised olefins with the achievement of excellent enantioselectivities (> or = 99%) in most cases and turnover frequency (TOF) values of up to > or = 20,000 h(-1). These results substantiate the practical utility of readily accessible Quinaphos-type ligands, which belong to the most active and selective category of ligands for Rh-catalysed hydrogenation known to date.
Singapore Indian Eye Study‐2: methodology and impact of migration on systemic and eye outcomes (2017)

In both SINDI and SINDI-2, second-generation immigrants had lower prevalence of cardiovascular risk factors except smoking and obesity compared with first-generation immigrants. The final report will confirm if these differences between generations are evident with regard to eye diseases.
Reproduction of sound source directivity for future audio applications (2004)

cote interne IRCAM: Warusfel04a
Multiplanes (2018)

The presence of a third dimension makes accurate drawing in virtual reality (VR) more challenging than 2D drawing. These challenges include higher demands on spatial cognition and motor skills, as well as the potential for mistakes caused by depth perception errors. We present Multiplanes, a VR drawing system that supports both the flexibility of freehand drawing and the ability to draw accurate shapes in 3D by affording both planar and beautified drawing. The system was designed to address the above-mentioned challenges. Multiplanes generates snapping planes and beautification trigger points based on previous and current strokes and the current controller pose. Based on geometrical relationships to previous strokes, beautification trigger points serve to guide the user to reach specific positions in space. The system also beautifies user's strokes based on the most probable intended shape while the user is drawing them. With Multiplanes, in contrast to other systems, users do not need to manually activate such guides, allowing them to focus on the creative process.
Volatile Hexavalent Oxo-amidinate Complexes: Molybdenum and Tungsten Precursors for Atomic Layer Deposition (2016)

New complexes MoO2(tBuAMD)2 (1) and WO2(tBuAMD)2 (2) (AMD = acetamidinato) are synthesized and fully characterized as precursors for atomic layer deposition (ALD). They contain metal-oxo functionalities not previously utilized in ALD-type growth processes and are fully characterized by 1H and 13C NMR, X-ray diffraction (XRD), Fourier transform infrared, thermogravimetric analysis, single-crystal XRD, and elemental analysis. Guided by quartz-crystal microbalance studies, ALD growth methodologies for both complexes have been developed. Remarkably, these isostructural compounds exhibit dramatic differences in ALD properties. Using 1 and O3, amorphous, ultrathin molybdenum oxynitride (MoON) films are grown on Si(100) wafers. Using 2 and H2O yields amorphous WO3 films on Si(100) wafers that crystallize as WO3 nanowires upon annealing. Although 1/H2O and 2/O3 growth was attempted, effective ALD growth could only be obtained with 1/O3 and 2/H2O, underscoring reactivity differences in these precursors. Film thicknesses, compositions, and optical and electrical parameters are characterized by variable angle spectroscopic ellipsometry, X-ray reflectivity, grazing incidence X-ray diffraction, X-ray photoelectron spectroscopy, ultraviolet photoelectron spectroscopy, and atomic force microscopy techniques. The hitherto unknown ALD chemistry of group VI metal-oxo compounds lays a foundation for their use in the ALD synthesis of heterogeneous catalysts.
Development of a hepatitis B vaccine from transformed yeast cells. (1987)

The production in yeast cells of the recombinant DNA hepatitis B vaccine of SmithKline Biologicals involves an optimized fermentation process followed by cell disruption and extraction, together with other soluble yeast components of the surface antigen of the hepatitis B virus. The subsequent purification process includes precipitation steps, ion exchange and gel permeation chromatography, and caesium chloride ultracentrifugation. The yeast-derived antigen occurs as spherical particles containing the non-glycosylated HBsAg polypeptide, lipid, and Tween 20. The purity of the polypeptide is above 95% and confirmed by the absence of an immune response to yeast-derived contaminants in vaccinees. Yeast DNA levels were less than 10 pg/vaccine dose. Various biochemical analyses showed that the recombinant polypeptide was faithfully expressed and did not undergo unwanted processing or degradation during fermentation or purification. These results indicate that the recombinant HBsAg can be effectively produced in yeast and processed to a high degree of purity to yield HBsAg particles displaying most of the characteristic properties of plasma-derived HBsAg.
Transparent organic bistable memory device with pure organic active material and Al/indium tin oxide electrode (2008)

Transparent organic bistable memory devices (OBDs) were developed by employing indium tin oxide (ITO) as an anode and a cathode for OBD. A cathode structure of aluminum (Al)/ITO was used and bistability could be realized with pure polyphenylenevilylene based polymer active material without any metal nanoparticle. Transmittance of over 50% could be obtained in Al/ITO based OBD at an Al thickness of 10nm, and an average on/off ratio around 100 was observed.
Expanding the phenotypic spectrum of NAA10-related neurodevelopmental syndrome and NAA15-related neurodevelopmental syndrome (2023)

Amino-terminal (Nt-) acetylation (NTA) is a common protein modification, affecting 80% of cytosolic proteins in humans. The human essential gene, NAA10, encodes for the enzyme NAA10, which is the catalytic subunit in the N-terminal acetyltransferase A (NatA) complex, also including the accessory protein, NAA15. The full spectrum of human genetic variation in this pathway is currently unknown. Here we reveal the genetic landscape of variation in NAA10 and NAA15 in humans. Through a genotype-first approach, one clinician interviewed the parents of 56 individuals with NAA10 variants and 19 individuals with NAA15 variants, which were added to all known cases (N = 106 for NAA10 and N = 66 for NAA15). Although there is clinical overlap between the two syndromes, functional assessment demonstrates that the overall level of functioning for the probands with NAA10 variants is significantly lower than the probands with NAA15 variants. The phenotypic spectrum includes variable levels of intellectual disability, delayed milestones, autism spectrum disorder, craniofacial dysmorphology, cardiac anomalies, seizures, and visual abnormalities (including cortical visual impairment and microphthalmia). One female with the p.Arg83Cys variant and one female with an NAA15 frameshift variant both have microphthalmia. The frameshift variants located toward the C-terminal end of NAA10 have much less impact on overall functioning, whereas the females with the p.Arg83Cys missense in NAA10 have substantial impairment. The overall data are consistent with a phenotypic spectrum for these alleles, involving multiple organ systems, thus revealing the widespread effect of alterations of the NTA pathway in humans.
Risk of Adverse Birth Outcome After Group B Meningococcal Disease (2009)

The results do not support the proposal that GBM is associated with immunoreactive disease that may affect the health of the offspring and are consistent with previous findings that GBM disease is not associated with an increased risk of autoimmune disease.
RADIOLOGIC CASE STUDY (2002)

A wide variety of inflammatory, infectious, metabolic, and neoplastic diseases can affect the sacroiliac joints. Early in their course, some of these diseases produce only subtle and nonspecific signs and symptoms. Demonstration of characteristic joint changes, knowledge of specific clinical manifestations, and familiarity with imaging modalities can lead to early diagnosis and treatment of these patients.
Reductive Elimination as a Mechanism for Purging a Lean NOx Trap (2006)

&lt;div class="htmlview paragraph"&gt;The mechanism for the purging of a lean NO&lt;sub&gt;x&lt;/sub&gt; trap has been investigated. For realistic purge times (e.g., 2 to 5 seconds), the stored NO&lt;sub&gt;x&lt;/sub&gt; species do not decompose simply from equilibrium considerations (i.e., from the drop in O&lt;sub&gt;2&lt;/sub&gt; and NO concentrations during the rich purge). Instead, the decomposition of stored NO&lt;sub&gt;x&lt;/sub&gt; is promoted by the reductants in the exhaust by a process referred to as reductive elimination. H&lt;sub&gt;2&lt;/sub&gt; is far more effective than CO or C&lt;sub&gt;3&lt;/sub&gt;H&lt;sub&gt;6&lt;/sub&gt; for promoting this reductive elimination, particularly at low temperatures (e.g., 250°C). As long as H&lt;sub&gt;2&lt;/sub&gt; is available in the feedgas, H&lt;sub&gt;2&lt;/sub&gt;O does not participate in the reductive elimination. However, if CO is the only reductant, H&lt;sub&gt;2&lt;/sub&gt;O is needed to convert some of the CO to H&lt;sub&gt;2&lt;/sub&gt; through the water-gas-shift reaction. H&lt;sub&gt;2&lt;/sub&gt;O is also important for the efficient storage of NO&lt;sub&gt;x&lt;/sub&gt; during lean operation, possibly by enhancing the spillover of NO&lt;sub&gt;2&lt;/sub&gt; from a precious metal site to a NO&lt;sub&gt;x&lt;/sub&gt; storage site. The kinetics of the reaction between H&lt;sub&gt;2&lt;/sub&gt; and the stored NO&lt;sub&gt;x&lt;/sub&gt; have been studied with a model Ba/Pt/Al&lt;sub&gt;2&lt;/sub&gt;O&lt;sub&gt;3&lt;/sub&gt; catalyst.&lt;/div&gt;
<title>In-situ plasma diagnostic investigations of single-wall carbon nanotube synthesis by laser ablation of C-Ni-Co targets</title> (2000)

Single-wall carbon nanotubes are formed by Nd:YAG laser vaporization of a graphite/(1 at.% Ni, 1 at.% Co) target into flowing argon (500 Torr) within a quartz tube furnace (1000 degrees Celsius). Here, this process is investigated for the first time with time-resolved laser-induced luminescence imaging and spectroscopy of Co atoms, C<SUB>2</SUB> and C<SUB>3</SUB> molecules, and clusters. These measurements under actual synthesis conditions show that the plume of vaporized material is segregated and confined within a vortex ring which maintains an approximately 1 cm<SUP>3</SUP> volume for several seconds. Using time-resolved spectroscopy and spectroscopic imaging, the time for conversion of atomic and molecular species to clusters was measured for both carbon (200 microseconds) and cobalt (2 ms). This rapid conversion of carbon to nanoparticles, combined with transmission electron microscopy analysis of the collected deposits, indicate that nanotube growth occurs during several seconds of time from a feedstock of mixed nanoparticles in the gas-suspended plume. By adjusting the time spent by the plume within the high- temperature zone using these in situ diagnostics, single- walled nanotubes of controlled length were grown at an estimated rate of 0.2 micrometers /s.
PCE Communication Protocol (PCEP) Extensions for Label Switched Path (LSP) Scheduling with Stateful PCE (2020)

This document defines a set of extensions needed to the stateful Path
Computation Element (PCE) communication Protocol (PCEP), so as to
enable Labeled Switched Path (LSP) path computation, activation, setup
and deletion based on scheduled time intervals for the LSP and the
actual network resource usage in a centralized network environment as
stated in RFC 8413.
A hepatitis C virus (HCV) NS3/4A protease-dependent strategy for the identification and purification of HCV-infected cells (2006)

As a tool for the identification and/or purification of hepatitis C virus (HCV)-infected cells, a chimeric form of the Gal4VP16 transcription factor was engineered to be activated only in the presence of the HCV NS3/4A protease and to induce different reporter genes [choramphenical acetyltransferase (CAT), green fluorescent protein (GFP) and the cell-surface marker H-2K(k)] through the (Gal4)(5)-E1b promoter. For this, the NS5A/5B trans-cleavage motif of HCV of genotype 1a was inserted between Gal4VP16 and the N terminus of the endoplasmic reticulum (ER)-resident protein PERK, and it was demonstrated that it could be cleaved specifically by NS3/4A. Accordingly, transient transfection in tetracycline-inducible UHCV-11 cells expressing the HCV polyprotein of genotype 1a revealed the migration of the Gal4VP16 moiety of the chimera from the ER to the nucleus upon HCV expression. Activation of the chimera provoked specific gene induction, as shown by CAT assay, first in UHCV-11 cells and then in Huh-7 cells expressing an HCV replicon of genotype 1b (Huh-7 Rep). In addition, the GFP reporter gene allowed rapid fluorescence monitoring of HCV expression in the Huh-7 Rep cells. Finally, the chimera was introduced into Huh-7.5 cells infected with cell culture-generated HCV JFH1 (genotype 2a), allowing the purification of the HCV-infected cells by immunomagnetic cell sorting using H-2K(k) as gene reporter. In conclusion, the Gal4VP16 chimera activation system can be used for the rapid identification and purification of HCV-infected cells.
On Wireless Scheduling With Partial Channel-State Information (2012)

A time-slotted queueing system for a wireless downlink with multiple flows and a single server is considered, with exogenous arrivals and time-varying channels. It is assumed that only one user can be serviced in a single time slot. Unlike much recent work on this problem, attention is drawn to the case where the server can obtain only partial information about the instantaneous state of the channel. In each time slot, the server is allowed to specify a single subset of flows from a collection of observable subsets, observe the current service rates for that subset, and subsequently pick a user to serve. The stability region for such a system is provided. An online scheduling algorithm is presented that uses information about marginal distributions to pick the subset and the Max-Weight rule to pick a flow within the subset, and which is provably throughput-optimal. In the case where the observable subsets are all disjoint, or where the subsets and channel statistics are symmetric, it is shown that a simple scheduling algorithm-Max-Sum-Queue-that essentially picks subsets having the largest squared-sum of queues, followed by picking a user using Max-Weight within the subset, is throughput-optimal.
Low temperature wafer bonding for wafer-level 3D integration (2014)

This work presents new results on low temperature wafer bonding processes. Low temperature Cu-Cu thermo-compression bonding was successfully performed at process temperatures lower than 200°C. A process flow was developed for stacking thin Si wafers (<;25 μm) using a combination of temporary bonding with rigid carrier and plasma activated wafer bonding. Together with high accuracy optical alignment technology the two processes can be used to address the needs of manufacturing processes based on TSV technology.
Evaluation of a QRS scoring system for estimating myocardial infarct size. I. Specificity and observer agreement. (1982)

We evaluated a simplified version of a previously developed QRS scoring system for estimating infarct size using observations of Q- and R-wave durations and R/Q and R/S amplitude ratios in the standard 12-lead ECG. Groups of subjects with a minimal likelihood of having myocardial infarcts and minimal likelihood of having common noninfarction sources of QRS modification were studied to establish the specificity of each of the 37 criteria. Only two criteria required modification to achieve 95% specificity. These 37 criteria form the basis of a 29-point QRS scoring system. A 98% specificity was achieved when a score of more than 2 points was required to identify a myocardial infarct. Fifty patients were studied to determine the intra- and interobserver agreement with this scoring system. Each criterion achieved at least 91% intra- and interobserver agreement. These impressive levels of specificity and observer agreement must be matched by high sensitivity of the scoring system and a good correlation between the point score and infarct size in patients with proven infarcts if the point score is to be useful for detecting and sizing infarcts. Sensitivity and correlation between point score and infarct size are evaluated in later studies in this series. The standard ECG is inexpensive and can be obtained repetitively and noninvasively; its QRS complex may be an important means of estimating the size, presence and location of myocardial infarcts.
Bonded Multijunction Photovoltaics to Improve Efficiency and Performance (2012)

Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text J. E. Bowers, C. Lin, W. E. McMahon, J. S. Ward, J. F. Geisz, M. W. Wanlass, J. J. Carapella, W. Olavarria, M. Young, M. A. Steiner, R. M. Frances, A. E. Kibbler, A. Duda, J. M. Olson, E. E. Perl, and D. J. Friedman, "Bonded Multijunction Photovoltaics to Improve Efficiency and Performance," in Asia Communications and Photonics Conference, OSA Technical Digest (online) (Optica Publishing Group, 2012), paper ATh3F.3. Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
Convergence in Networked Recursive Identification with Output Quantization (2018)

This paper analyzes conditions for global parametric convergence of a networked recursive identification algorithm. The FIR based algorithm accounts for networked delay and signal quantization. The paper constructs counterexamples to parametric convergence using low order dynamic models and an asymmetric binary quantizer. The associated ODEs of the first order model are analysed with analytical methods and by numerical simulation. In particular, the analysis proves that parametric convergence does not occur in case the input signal distribution is discrete taking a finite number of values, the problem is symmetric, or in case the input signal distribution, dynamic gain and switch point are such that there is no signal energy in an arbitrary small neighborhood of any switch point. Global parametric convergence is also proved for one of the low order cases.
Electrochemical-Etching Approach to Achieving Ultrathin FeSe Films (2016)

Electric double layer transistor (EDLT) has attracted attentions over the decade as a useful tool to induce and control fascinating many physical properties at two dimensional (2D) materials surface based on its giant capacitance. This paper highlights another aspect of EDLT: electrochemical reaction as a method to achieve ultrathin films. Precise tuning of reactivity of electrochemical etching between ionic liquid and solid surface makes it possible to peel off 2D materials layer-by-layer. This technique was applied to an iron-based superconductor FeSe in EDLT towards the observation of high temperature superconductivity in ultra-thin film form.
Supplementary Video 1 from p38γ Promotes Breast Cancer Cell Motility and Metastasis through Regulation of RhoC GTPase, Cytoskeletal Architecture, and a Novel Leading Edge Behavior (2023)

&lt;p&gt;AVI file - 2.4MB&lt;/p&gt;