gebhart/patrepeval huggingface dataset:
Management: Global positioning and wireless dispatching (1996)

Over the last several years, my company has been supplying many service companies with wireless dispatching solutions. Recently the impact of the system has been greatly increased with the introduction of a GPS (Global Position Systems) interface. This adds visual recognition as to the whereabouts of each vehicle within the customer service area. The only equipment required in the field for GPS is a transmit/receive device and a wireless modem, one mounted out of the way in the vehicle (under the seat) and a {open_quotes}hockey puck{close_quotes} size unit on the roof of the vehicle. The GPS received unit and wireless modem are used to retrieve the longitude, latitude and ground speed coordinates and transmit them back to the host system.
Cross‐plane information sharing for QoS in satellite–terrestrial integrated packet networks (2010)

Abstract This paper introduces a standards‐based Quality‐of‐Service (QoS) architecture for satellite and terrestrial IP packet network integration to facilitate the evolution of the next generation integrated networks. Cross‐plane information sharing can extend the reach of cross‐layer improvements, typically applied for enhancing throughput and robustness in the wireless networks. Besides supporting real‐time interactive applications for all users, such a QoS architecture can also provide a prioritization framework for enhanced service assurance. The satellite packet transport operates in a spectral, power, and hardware resource constrained environment. It needs specific functions for packet classification, scheduling, and propagation, all operating within the broader context of dynamic resource allocations at the media access layer for transporting individual packets and their aggregates. Additional information, made available to these networking functions across the data, control, and management planes can facilitate key decision making at the individual packet flow level with the use of formal connection admission control (CAC). Our QoS scheme links the data and management planes with the use of IP differentiated services (Diffserv) information in the packet headers. Originally designed for packet traffic aggregates, Diffserv can be leveraged to provide QoS for the individual packet flows at specific data rates and packet drop sensitivity. This QoS architecture has been validated with a pioneering regenerative packet processing satellite system and it is also suitable for other networks that support flow‐level CAC, operating under dynamic network capacity management. Copyright © 2010 John Wiley &amp; Sons, Ltd.
Révision nomenclaturale des noms d’ascomycètes publiés par Émile Boudier. 1re partie : 1869 à 1904 (2011)

A nomenclatural revision of the names of specific or infraspecific taxa, among the Ascomycota, published by Boudier is proposed. It allows to precise or to correct bibliographic citations or nomenclatural status of these names adopted by the successive authors in the sight of current rules of the fungal nomenclature
Interrogation of Noncovalent Complexes by ESI‐MS: A Powerful Platform for High Throughput Drug Discovery (2007)

This chapter contains sections titled: Analysis of Noncovalent Complexes by ESI-MS Solution Conditions Proteins Oligonucleotides Multitarget Affinity/Specificity Screening Multitarget Affinity/Specificity Screening in a High Throughput Format Affinity/Specificity SAR by MS Future Directions
Throughput Limits and Multiuser Diversity of Multiantenna Spectrum Sharing Networks (2011)

This paper investigates the secondary multiuser diversity in spectrum sharing networks. We show that by exploiting the fading nature of interference links, the secondary system to efficiently utilize the spectrum while complying with constraints imposed by the primary system. More precisely, as the number of secondary users increases, the throughput grows logarithmically in a secondary multiple-access channel (MAC) and double-logarithmically in a secondary broadcast channel (BC). The multiuser diversity may also reduce the interference on the primary asymptotically to zero; the tradeoff between throughput enhancement and interference reduction is characterized. Finally, we results show that for the secondary MAC the growth rate of throughput decreases linearly with the number of primary users (constraints), while for the secondary BC the growth rate is unaffected by the number of primary constraints.
Development of the second “add-on PET” prototype: A head coil with DOI-PET detectors for MRI (2016)

We are developing a PET/MRI system based on 4-layered depth-of-interaction (DOI) detectors integrated with a birdcage RF-coil. The PET detectors are placed close to the objective to achieve both high sensitivity and high spatial resolution even at the edge of the field of view (FOV). In a previous study, we reported the first prototype which had a single detector ring to show a proof-of-concept and lower than 1.6 mm spatial resolution was achieved. However, the axial FOV of the prototype was only 1 cm, which could not be extended due to the size of the readout circuit boards. In this paper, we finally constructed a new RF-coil for the second prototype, which is combined with 24 DOI-PET detectors. We evaluated performance in simultaneous measurements. The second prototype consisted of an RF-coil and 24 PET detector units with two PET detectors each. The detector units were shielded with carbon fiber shielding boxes. Each PET detector consisted of a 14 × 14 × 4-layer array of lutetium fine silicate (LFS) crystals (1.9 mm × 1.9 mm × 4.0 mm), an 8 × 8 multi-pixel photon counter module (MPPC, S11206-0808FC(X)) and a readout circuit board with an ASIC. The RF coil was dedicated to a 3T MRI (MAGNETOM Verio, Siemens). We conducted performance tests of the second prototype in simultaneous measurements. As a result, the influence of the MRI measurements on the PET performance was found to be negligible. In addition, secondary magnetic field due to the eddy current effect can be reduced, compared with the previous prototype system.
ChemInform Abstract: Optically Active Bipyridines in Asymmetric Catalysis. (1990)

Abstract The synthesis of the (R,R)‐configurated title compounds (I) is described and the X‐ray structure is reported for the adduct (Ib)·CoCl 2 (space group C2, Z=2).
DMRZ: a directly modulated 10-Gb/s RZ source for ultralong-haul WDM systems (2002)

We demonstrate a 10-Gb/s return-to-zero transmitter with 5-dBm average power, 40-ps full-width at half-maximum pulsewidth,12-dB contrast ratio, and /spl plusmn/1-GHz wavelength stability at 1550 nm. The source comprises an FM modulated distributed feedback laser and a fiber Bragg grating optical discriminator module with tap monitors.
Comparative vascular pharmacology of the atriopeptins. (1985)

The atriopeptins are potent relaxants of norepinephrine-constricted aortic strips or are dilators of renal blood vessels in isolated perfused rat kidneys that are constricted by norepinephrine. This vasorelaxant property of the atriopeptins requires the presence of phenylalanine arginine (i.e., atriopeptin II, III, or ser-leu-arg-arg atriopeptin III) residues in the carboxy terminus which are considerably more effective than atriopeptin I (the 21 amino acid peptide which lacks the phe-arg C-terminus) or the core peptide (residues 3-19). However, these artificially in vitro precontracted preparations do not accurately predict the vascular effectiveness of the atriopeptins in intact rats. Intravenous administration of the atriopeptins (including atriopeptin I) to anesthetized rats produces concentration-dependent hypotension, a selective decrease in renal resistance in low doses (determined with microspheres), and pronounced diuresis. At higher doses, atriopeptins increase blood flow in other vascular beds. On the other hand, in the anesthetized dog, injection (intraarterially) of the phe-arg-containing peptides produces a concentration-dependent increase in both renal blood flow and sodium excretion, whereas atriopeptin I is inactive. Although there is a species difference in responsiveness to atriopeptin I, these data demonstrate a direct correlation between the renal vasodilation and diuresis produced by this novel family of atrial peptides.
Projected Mushroom Type Phase‐Change Memory (2021)

Abstract Phase‐change memory devices have found applications in in‐memory computing where the physical attributes of these devices are exploited to compute in places without the need to shuttle data between memory and processing units. However, nonidealities such as temporal variations in the electrical resistance have a detrimental impact on the achievable computational precision. To address this, a promising approach is projecting the phase configuration of phase change material onto some stable element within the device. Here, the projection mechanism in a prominent phase‐change memory device architecture, namely mushroom‐type phase‐change memory, is investigated. Using nanoscale projected Ge 2 Sb 2 Te 5 devices, the key attributes of state‐dependent resistance, drift coefficients, and phase configurations are studied, and using them how these devices fundamentally work is understood.
Introduction to the Special Issue on Models, Theory, and Codes for Relaying and Cooperation in Communication Networks [Guest Editorial] (2007)

The thirty-four papers in this special issue are devoted to models, theories, and codes for relaying and cooperation in communication networks. The demand for large, more efficient, reliable, and cost effective communication networks is motivating new network architectures for cellular and wireless communications as well as cognitive radio and sensor networks.
Non-coherent distributed space-time processing for multiuser cooperative transmissions (2005)

User cooperation can provide spatial transmit diversity gains, enhance coverage and potentially increase capacity. Existing works have focused on two-user cooperative systems with perfect channel state information at the receivers. In this paper, we develop several distributed space-time processing schemes for general TV-user cooperative systems, which do not require channel state information at either relays or destination. We prove that full spatial diversity gain can be achieved in such systems. Simulations demonstrate that these cooperative schemes achieve significant performance gain.
Fluidic force microscopy to access the interactions between gaz/liquid and biological interfaces (2020)

International audience
A structured approach to uncertainty analysis of predictive models of engine-out NOx emissions (2017)

Predictive models of engine-out NOx emissions continue to be a topic of active research in the diesel powertrain community. Renewed interest in the use of in-cylinder pressure sensor has presented an opportunity for improving these models through the availability of direct information about the in-cylinder combustion process. Despite several research efforts in this domain seen in open literature, there is a significant paucity of work that reports on the uncertainty analysis of such models. These models are typically designed for real-time implementation, and the model prediction is often used for control and/or diagnostic functions. It is therefore critical to establish the expected error bounds or an error probability distribution and the model prediction for consideration during the design of relevant control and/or diagnostic algorithms.
DRL-based Slice Placement Under Non-Stationary Conditions (2021)

International audience
Fast Mapping of Flexibility Regions at TSO-DSO Interfaces under Uncertainty (2022)

The gradual decommissioning of fossil fuel-driven power plants, that traditionally provide most operational flexibility in power systems, has led to more frequent grid stability issues. To compensate for the lack of flexible resources, Distributed Energy Resources (DERs) in distribution networks can be employed. To facilitate the use of DERs, the aggregated flexibility in a distribution grid is commonly represented on a $PQ$-plane displaying the feasible active and reactive power exchange with the upstream grid. This paper proposes a fast feasible operating region mapping mechanism that utilizes a linear power flow approximation in combination with linearized generator, current, and voltage constraints to construct a high-dimensional polyhedral feasible set of DER power injections. The obtained polytope is projected onto the $PQ$-plane using Fourier-Motzkin Elimination to represent the aggregate network flexibility. Additionally, uncertainty in DER generation is addressed using chance-constraints. Our analysis of a modified 33-bus IEEE test system demonstrates that the proposed method obtains more accurate approximations than former geometric methods and is ten times faster than the tested optimization-based method.
Idiotype vaccine therapy (BiovaxID) in follicular lymphoma in first complete remission: Phase III clinical trial results (2009)

2 Background: In previous trials, tumor-specific purified idiotype (Id) protein conjugated to keyhole limpet hemocyanin (KLH) administered with granulocyte-monocyte colony-stimulating factor (GM-CSF) induced follicular lymphoma (FL)-specific immune responses and molecular remissions (Nat Med. 1999;5:1171–7). Methods: We conducted a prospective randomized double-blind placebo-controlled multicenter phase III study of patient-specific autologous tumor-derived Id vaccine in advanced stage previously untreated FL patients (pts) with a lymph node adequate for vaccine production (≥ 2cm). Pts achieving complete response (CR) or complete response unconfirmed (CRu) after chemotherapy (PACE: prednisone, doxorubicin, cyclophosphamide, etoposide) were stratified by International Prognostic Index risk group and randomized 2:1 to receive either vaccination with Id-KLH/GM-CSF or control (KLH/GM-CSF). The primary endpoint was disease free survival. Results: 234 pts were enrolled; 177 (76%) achieved CR/CRu and were randomized. Of 177 randomized pts, 117 maintained CR/CRu ≥ 6 mo per protocol requirement and then received at least one dose of vaccine, 55 relapsed before vaccination, 4 were vaccine manufacturing failures, and 1 violated protocol. Pts who received ≥ one vaccine dose constituted the modified intent-to-treat population for determination of efficacy. 76 pts received Id-KLH/GM-CSF and 41 pts received the control (KHL/GM-CSF). No serious adverse events were attributed to Id vaccination. At a median follow-up of 56.6 mo (range 12.6 –89.3 mo), median time to relapse after randomization for the Id-KLH/GM-CSF arm was 44.2 mo, versus 30.6 mo for the control arm (p = 0.045; HR = 1.6). Conclusions: Id vaccination after a chemotherapy-induced remission of ≥ 6 mo prolongs remission duration in pts with FL. Compared to other phase III Id vaccine trials, the positive outcome of this study may reflect application of Id vaccine in pts in CR/CRu or use of hybridomas to produce Id. Genomic and immune response analyses are planned on residual autologous tumor and blood samples. Additional studies of this patient-specific vaccine in FL pts pretreated with anti-CD20 antibody-containing chemotherapy are indicated. Author Disclosure Employment or Leadership Consultant or Advisory Role Stock Ownership Honoraria Research Funding Expert Testimony Other Remuneration Accentia Biopharmaceuticals, Biovest International Antigenics, Biogen Idec, Biovest International, Genentech Xeme Biopharma Biovest International
The Shared Crosstalk of Multiple Pathways Involved in the Inflammation between Rheumatoid Arthritis and Coronary Artery Disease Based on a Digital Gene Expression Profile (2014)

Rheumatoid arthritis (RA) and coronary artery disease (CAD) are both complex inflammatory diseases, and an increased prevalence of CAD and a high rate of mortality have been observed in RA patients. But the molecular mechanism of inflammation that is shared between the two disorders is unclear. High-throughput techniques, such as transcriptome analysis, are becoming important tools for genetic biomarker discovery in highly complex biological samples, which is critical for the diagnosis, prognosis, and treatment of disease. In the present study, we reported one type of transcriptome analysis method: digital gene expression profiling of peripheral blood mononuclear cells of 10 RA patients, 10 CAD patients and 10 healthy people. In all, 213 and 152 differently expressed genes (DEGs) were identified in RA patients compared with normal controls (RA vs. normal) and CAD patients compared with normal controls (CAD vs. normal), respectively, with 73 shared DEGs between them. Using this technique in combination with Ingenuity Pathways Analysis software, the effects on inflammation of four shared canonical pathways, three shared activated predicted upstream regulators and three shared molecular interaction networks were identified and explored. These shared molecular mechanisms may provide the genetic basis and potential targets for optimizing the application of current drugs to more effectively treat these diseases simultaneously and for preventing one when the other is diagnosed.
TAGME: on-the-fly annotation of short text fragments (by Wikipedia entities) (2010)

In this paper we address the problem of accurately and efficiently cross-referencing text fragments with Wikipedia pages, in a way that structured knowledge is provided about the (unstructured) input text by resolving synonymy and polysemy. We take inspiration from the invited talk of Chakrabarti at WSDM 2010, and extend his proposed scenario from the annotation of entire documents to the annotation of short texts, such as snippets of search-engine results, tweets, news, etc.. These short and poorly composed texts pose new challenges in terms of efficiency and effectiveness of the annotation process, that we address by proposing TAGME, the first system that performs an accurate and on-the-fly annotation of these short textual fragments. A large set of experiments shows that TAGME significantly outperforms state-of-the-art algorithms [Milne and Witten 2008, Chakrabarty et al. 2009] when they are adapted to work on short texts, and surprisingly, it results competitive (if not superior!) on long texts with the plus of being faster.
Generation of Higher Order Modes in a Rectangular Duct (2004)

Advanced noise control methodologies to reduce sound emission from aircraft engines take advantage of the modal structure of the noise in the duct. This noise is caused by the interaction of rotor wakes with downstream obstructions such as exit guide vanes. Mode synthesis has been accomplished in circular ducts and current active noise control work has made use of this capability to cancel fan noise. The goal of the current effort is to examine the fundamental process of higher order mode propagation through an acoustically treated, curved duct. The duct cross-section is rectangular to permit greater flexibility in representation of a range of duct curvatures. The work presented is the development of a feedforward control system to generate a user-specified modal pattern in the duct. The multiple-error, filtered-x LMS algorithm is used to determine the magnitude and phase of signal input to the loudspeakers to produce a desired modal pattern at a set of error microphones. Implementation issues, including loudspeaker placement and error microphone placement, are discussed. Preliminary results from a 9-3/8 ” by 21 ” duct, using 12 loudspeakers and 24 microphones, are presented. These results demonstrate the ability of the control system to generate a user-specified mode while suppressing undesired modes. 1.
Data from Adjuvant Imatinib in Patients with GIST Harboring Exon 9 KIT Mutations: Results from a Multi-institutional European Retrospective Study (2023)

&lt;div&gt;AbstractPurpose:&lt;p&gt;The effect of high-dose imatinib (800 mg/day) on survival in the adjuvant treatment of patients with resected KIT exon 9–mutated gastrointestinal stromal tumors (GIST) is not established. Here, the association of dose and other clinicopathologic variables with survival was evaluated in a large multi-institutional European cohort.&lt;/p&gt;Experimental Design:&lt;p&gt;Data from 185 patients were retrospectively collected in 23 European GIST reference centers. Propensity score matching (PSM) and inverse-probability of treatment weighting (IPTW) were used to account for confounders. Univariate and multivariate unweighted and weighted Cox proportional hazard regression models were estimated for relapse-free survival (RFS), modified-RFS (mRFS) and imatinib failure-free survival (IFFS). Univariate Cox models were estimated for overall survival.&lt;/p&gt;Results:&lt;p&gt;Of the 185 patients, 131 (70.8%) received a starting dose of 400 mg/d and the remaining 54 (29.2%) a dose of 800 mg/d. Baseline characteristics were partially unbalanced, suggesting a potential selection bias. PSM and IPTW analyses showed no advantage of imatinib 800 mg/d. In the weighted multivariate Cox models, high-dose imatinib was not associated with the survival outcomes [RFS: hazard ratio (HR), 1.24; 95% confidence interval (CI), 0.79–1.94; mRFS: HR, 1.69; 95% CI, 0.92–3.10; IFFS: HR, 1.35; 95% CI, 0.79–2.28]. The variables consistently associated with worse survival outcomes were high mitotic index and nongastric tumor location.&lt;/p&gt;Conclusions:&lt;p&gt;In this retrospective series of patients with KIT exon 9–mutated GIST treated with adjuvant imatinib, a daily dose of 800 mg versus 400 mg did not show better results in terms of survival outcomes. Prospective evaluation of the more appropriate adjuvant treatment in this setting is warranted.&lt;/p&gt;&lt;/div&gt;
Synthesis of the (3R,6S)-3-Amino-6-(2,3-difluorophenyl)azepan-2-one of Telcagepant (MK-0974), a Calcitonin Gene-Related Peptide Receptor Antagonist for the Treatment of Migraine Headache (2008)

Two novel routes have been developed to the (3 R,6 S)-3-amino-6-(2,3-difluorophenyl)-1-(2,2,2-trifluoroethyl)azepan-2-one 2 of the CGRP receptor antagonist clinical candidate telcagepant (MK-0974, 1). The first employs a ring-closing metathesis of the styrene 7 as the key reaction, while the second makes use of a highly diastereoselective Hayashi-Miyaura Rh-catalyzed arylboronic acid addition to nitroalkene 16. The latter route has been implemented to produce multigram quantities of telcagepant for extensive preclinical evaluation.
Association Between Pharmacy Benefit Restrictions and Disease-Modifying Therapy Use in the Medicare Part D Program (2021)

Medicare beneficiaries with MS enrolled in restrictive Part D plans were less adherent to their DMT and had higher rates of MS-related outpatient visits.
VCSELs Advances and Future Prospects (1998)

Semiconductor diode lasers pervade our society in both the telecom and consumer electronics industry. A particular kind of laser diode — a verticle-cavity surface-emitting laser — is revolutionizing the capabilities of these tiny structures and their potential markets.
Solvent-Solute Interactions in Ionic Liquid Media: Electrochemical Studies of the Ferricenium-Ferrocene Couple (2003)

Electrochemical studies of the ferricenium/ferrocene ([Fc]+/[Fc]) redox couple have been carried out in ionic liquids containing the 1-butyl-3-methylimidazolium cation [C4mim]+ and the anions [CF3SO3]-, [N(SO2CF3)2]- and [PF6]-. The [Fc]+/[Fc] couple shows electrochemical reversibility in all cases, and controlled-potential electrolysis of ferrocene to the monocation is chemically reversible. The diffusion coefficients and Stokes-Einstein products of both the oxidized and the reduced species have been determined by using cyclic voltammetry, normal pulse voltammetry and rotating disk electrode voltammetry with both platinum and glassy carbon working electrodes. The solvodynamic radii of the diffusing species in each ionic liquid were estimated using the measured diffusion coefficients and a corrected version of the Stokes-Einstein equation. A dependency of the solvodynamic radii upon the anion of the ionic liquid was observed.