gebhart/patrepeval huggingface dataset:
Two Mechanisms of Hydrodynamic Lubrication in Textured Bearings (2006)

There is currently great interest in the use of textured bearings, where many tiny micropockets are incorporated in one of the bearing surfaces. Such texturing has been found to enhance load support and to reduce hydrodynamic friction in low load conditions, when the two surfaces have very low or zero convergence ratio, i.e. are essentially parallel. It is not immediately clear from hydrodynamic lubrication theory how a bearing with parallel surfaces and internal pockets can entrain any lubricant to form a hydrodynamic film and thus support load. However in a recent technical note the authors have shown that the occurrence of cavitation within micropockets results in suction of lubricant into the bearing, because the pressure inside the pockets is less than the surrounding, atmospheric pressure [1]. For parallel or very low convergence ratio bearings, this supply process replaces fluid entrainment as the main mechanism by which lubricant is drawn into the contact. In previous work this suction mechanism was demonstrated using a simple analytical approach for a 1D parallel bearing having a single pocket. The current paper extends this analytical method to convergent bearings having a single pocket and then applies a numerical solution of the first order Reynolds equation to solve for flow in multi-pocketed bearings. This enables the contribution of fluid suction on the load support of low convergence ratio bearings to be investigated.Copyright © 2006 by ASME
Fibrotic Response to Neoadjuvant Therapy Predicts Survival in Pancreatic Cancer and Is Measurable with Collagen-Targeted Molecular MRI (2020)

In humans, post-chemoradiation tumor fibrosis is associated with OS and DFS. In mice, our MR findings indicate that translation of collagen molecular MRI with CM-101 to humans might provide a novel imaging technique to monitor fibrotic response to therapy to assist with prognostication and disease management.
Inter-Cloud DDOS API Yang Model (2016)

This document defines a yang model that enables two Cloud providers to
exchange DDoS based on Inter-Cloud DDoS Mitigation API [draft- fang-
i2nsf-inter-cloud-ddos-mitigation-api-01].
Tryptophan‐96 in cytochrome P450 BM3 plays a key role in enzyme survival (2022)

Flavocytochrome P450 from Bacillus megaterium (P450<sub>BM3</sub> ) is a natural fusion protein containing reductase and heme domains. In the presence of NADPH and dioxygen the enzyme catalyses the hydroxylation of long-chain fatty acids. Analysis of the P450<sub>BM3</sub> structure reveals chains of closely spaced tryptophan and tyrosine residues that might serve as pathways for high-potential oxidizing equivalents to escape from the heme active site when substrate oxidation is not possible. Our investigations of the total number of enzyme turnovers before deactivation have revealed that replacement of selected tryptophan and tyrosine residues with redox inactive groups leads to a twofold reduction in enzyme survival time. Tryptophan-96 is critical for prolonging enzyme activity, suggesting a key protective role for this residue.
THE BENEFIT OF AEROBIC METHANOL UPTAKE ON DENITRIFICATION CAPACITY (2007)

THE BENEFIT OF AEROBIC METHANOL UPTAKE ON DENITRIFICATION CAPACITYThe Blue Plains Advanced Wastewater Treatment Plant (AWTP) in Washington, DC has a high rate activated sludge system followed by a suspended growth nitrification-denitrification system. Methanol is used for post-denitrification, because it is the least expensive synthetic compound available that does not leave residual biochemical oxygen demand (BOD) in the process effluent. The process achieves...Author(s)Michael E. ParsonsCharles B. BottDaniel B. OertherImre TakacsSudhir N. MurthySourceProceedings of the Water Environment FederationSubjectSession 48: DenitrificationDocument typeConference PaperPublisherWater Environment FederationPrint publication date Jan, 2007ISSN1938-6478SICI1938-6478(20070101)2007:15L.3526;1-DOI10.2175/193864707787973923Volume / Issue2007 / 15Content sourceWEFTECFirst / last page(s)3526 - 3555Copyright2007Word count336
Plasma Viremia and Cellular HIV-1 DNA Persist Despite Autologous Hematopoietic Stem Cell Transplantation for HIV-Related Lymphoma (2013)

A cure of HIV-1 has been achieved in one individual through allogeneic stem cell transplantation with a CCR5[INCREMENT]32 homozygous donor. Whether myeloablation and autologous stem cell transplantation for lymphoma in patients on suppressive antiretroviral therapy can eliminate HIV-1 reservoirs is unknown. Low-level plasma viremia and total HIV-1 DNA and 2-LTR circles in blood mononuclear cells were quantified after autologous transplantation in 10 patients on suppressive antiretroviral therapy using quantitative polymerase chain reaction assays capable of single-copy nucleic acid detection. Plasma viremia was detectable in 9 patients, whereas HIV-1 DNA was detectable in all 10 patients, indicating that HIV-1 had not been eliminated.
Synthesis and Reactivity of a Zwitterionic Palladium Allyl Complex Supported by a Perchlorinated Carboranyl Phosphine (2015)

A zwitterionic palladium complex of a phosphine bearing a perchlorinated carba-closo-dodecaborate anion as a ligand substituent is reported. A single-crystal X-ray diffraction study reveals that, in the solid state, one of the chlorides of the carborane cage occupies a coordination site of the square-planar complex. However, in solution, the P-carborane bond of the ligand is rapidly rotating at temperatures as low as -90 °C, which demonstrates the carborane substituent's weak coordinative ability even though this anion is covalently linked to the phosphine ligand. The complex is thermally stable and catalyzes the vinyl addition polymerization of norbornene.
Re: Akt-Mediated Phosphorylation of Bmi1 Modulates its Oncogenic Potential, E3 Ligase Activity, and DNA Damage Repair Activity in Mouse Prostate Cancer (2012)

No AccessJournal of UrologyInvestigative Urology1 Feb 2013Re: Akt-Mediated Phosphorylation of Bmi1 Modulates its Oncogenic Potential, E3 Ligase Activity, and DNA Damage Repair Activity in Mouse Prostate Cancer Anthony AtalaM.D. Anthony AtalaAnthony Atala More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.10.108AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "Re: Akt-Mediated Phosphorylation of Bmi1 Modulates its Oncogenic Potential, E3 Ligase Activity, and DNA Damage Repair Activity in Mouse Prostate Cancer." The Journal of Urology, 189(2), p. 771 © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 2February 2013Page: 771 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Anthony Atala More articles by this author Expand All Advertisement PDF DownloadLoading ...
Extending WLAN coverage via utility pipes (2005)

In this paper, we propose an inexpensive solution to the extension of wireless local area networks (WLAN) coverage. Our work shows that one can use antennas connected to the utility pipes (e.g., natural gas pipes, drinking water pipes, etc.) to extend the coverage of WLAN. Furthermore, this approach eliminates handovers from high to low data rate networks; e.g., handovers that occur from WLAN to a general packet radio service (GPRS) network. Therefore, the proposed approach avoids the drastic drop in the data rate when handovers occur from high to low data rate wireless networks. We also develop an analytical framework to evaluate the performance of the proposed approach.
eIMRT: a web platform for the verification and optimization of radiation treatment plans (2009)

The eIMRT platform is a remote distributed computing tool that provides users with Internet access to three different services: Monte Carlo optimization of treatment plans, CRT & IMRT treatment optimization, and a database of relevant radiation treatments/clinical cases. These services are accessible through a user-friendly and platform independent web page. Its flexible and scalable design focuses on providing the final users with services rather than a collection of software pieces. All input and output data (CT, contours, treatment plans and dose distributions) are handled using the DICOM format. The design, implementation, and support of the verification and optimization algorithms are hidden to the user. This allows a unified, robust handling of the software and hardware that enables these computation-intensive services. The eIMRT platform is currently hosted by the Galician Supercomputing Center (CESGA) and may be accessible upon request (there is a demo version at http://eimrt.cesga.es:8080/eIMRT2/demo; request access in http://eimrt.cesga.es/signup.html). This paper describes all aspects of the eIMRT algorithms in depth, its user interface, and its services. Due to the flexible design of the platform, it has numerous applications including the intercenter comparison of treatment planning, the quality assurance of radiation treatments, the design and implementation of new approaches to certain types of treatments, and the sharing of information on radiation treatment techniques. In addition, the web platform and software tools developed for treatment verification and optimization have a modular design that allows the user to extend them with new algorithms. This software is not a commercial product. It is the result of the collaborative effort of different public research institutions and is planned to be distributed as an open source project. In this way, it will be available to any user; new releases will be generated with the new implemented codes or upgrades.
Fast Nanoscale Surface Charge Mapping with Pulsed-Potential Scanning Ion Conductance Microscopy (2016)

A vast range of interfacial systems exhibit charge heterogeneities on the nanoscale. These differences in local surface charge density are challenging to visualize, but recent work has shown the scanning ion conductance microscope (SICM) to be a very promising tool to spatially resolve and map surface charge and topography via a hopping potential sweep technique with a single nanopipette probe, with harmonic modulation of a bias applied between quasi-reference counter electrodes in the nanopipette and bulk solution, coupled with lock-in detection. Although powerful, this is a relatively slow process, with limitations on resolution and the size of the images that can be collected. Herein, we demonstrate a new scanning routine for mapping surface charge and topography with SICM, which increases the data acquisition rate by an order of magnitude and with the potential for further gains. Furthermore, the method is simplified, eliminating the need for bias modulation lock-in detection, by utilizing a potential-pulse, chronoamperometric approach, with self-referencing calibration of the response at each pixel in the image. We demonstrate the application of this new method to both a model substrate and living PC-12 cells under physiological (high ionic strength) conditions, where charge mapping is most challenging (small Debye length). This work contributes significantly to the emergence of SICM as a multifunctional technique for simultaneously probing interfacial structure and function with nanometer resolution.
Preparation of (001) oriented Pb(Zr,Ti)O3 thin films and their piezoelectric applications (2007)

Preparation of (001) oriented Pb(Zr,Ti)O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> (PZT) thin films and their applications to a sensor and actuators were investigated. The (001) oriented PZT thin films were epitaxicially grown on (100)Pt/(100)MgO single crystal substrates by rf-magnetron sputtering. The PZT thin films on (100)Pt/(100)MgO buffer layer/glass substrates and (11 l)Pt/Ti/Si substrates also had high (001) orientation. All of these thin films showed the excellent piezoelectric properties without a poling treatment. These PZT thin films were applied to the angular rate sensor with a toning fork for a car navigation system, the dual-stage actuator for positioning a magnetic head of high-density hard disk drive (HDD) and the actuator for a inkjet printer head.
On the Identification of Bilinear Forms With the Wiener Filter (2017)

In this letter, the identification problem of bilinear forms with the Wiener filter is addressed. The contribution is twofold. First, a different approach is introduced, by defining the bilinear term with respect to the impulse responses of a spatiotemporal model, in the context of multiple-input/single-output systems. Second, two versions of the Wiener filter (namely direct and iterative) are developed in this context. Moreover, the advantage of the iterative Wiener filter is outlined as compared to the direct solution. The results of the simulations, which are performed from a system identification perspective, support the theoretical findings.
Determination of the solution O–O stretching frequency of a monomeric dioxygen cobalt complex by resonance Raman spectroscopy (1979)

T. Szymanski, T. W. Cape, R. P. Van Duyne and F. Basolo, J. Chem. Soc., Chem. Commun., 1979, 5 DOI: 10.1039/C39790000005
Effect of Crowding Agent Polyethylene Glycol on Lyotropic Chromonic Liquid Crystal Phases of Disodium Cromoglycate (2019)

Adding crowding agents such as polyethylene glycol (PEG) to lyotropic chromonic liquid crystals (LCLCs) formed by water dispersions of materials such as disodium cromoglicate (DSCG) leads to a phase separation of the isotropic phase and the ordered phase. This behavior resembles nanoscale condensation of DNAs but occurs at the microscale. The structure of condensed chromonic regions in crowded dispersions is not yet fully understood, in particular, it is not clear whether the condensed domains are in the nematic (N) or the columnar (C) state. In this study, we report on small angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) measurements of mixtures of aqueous solutions of DSCG with PEG and compare results to measurements of aqueous solutions of pure DSCG. X-ray measurements demonstrate that addition of PEG to DSCG in the N phase triggers appearance of the C phase that coexists with the isotropic (I) phase. Within the coexisting region, the lateral distance between the columns of the chromonic aggregates decreases as the temperature is increased.
DpiA Binding to the Replication Origin ofEscherichia coliPlasmids and Chromosomes Destabilizes Plasmid Inheritance and Induces the Bacterial SOS Response (2003)

The dpiA and dpiB genes of Escherichia coli, which are orthologs of genes that regulate citrate uptake and utilization in Klebsiella pneumoniae, comprise a two-component signal transduction system that can modulate the replication of and destabilize the inheritance of pSC101 and certain other plasmids. Here we show that perturbed replication and inheritance result from binding of the effector protein DpiA to A+T-rich replication origin sequences that resemble those in the K. pneumoniae promoter region targeted by the DpiA ortholog, CitB. Consistent with its ability to bind to A+T-rich origin sequences, overproduction of DpiA induced the SOS response in E. coli, suggesting that chromosomal DNA replication is affected. Bacteria that overexpressed DpiA showed an increased amount of DNA per cell and increased cell size-both also characteristic of the SOS response. Concurrent overexpression of the DNA replication initiation protein, DnaA, or the DNA helicase, DnaB-both of which act at A+T-rich replication origin sequences in the E. coli chromosome and DpiA-targeted plasmids-reversed SOS induction as well as plasmid destabilization by DpiA. Our finding that physical and functional interactions between DpiA and sites of replication initiation modulate DNA replication and plasmid inheritance suggests a mechanism by which environmental stimuli transmitted by these gene products can regulate chromosomal and plasmid dynamics.
Novel polyisobutylene stars. XXIII. Thermal, mechanical, and processing characteristics of poly(phenylene ether)/polydivinylbenzene(polyisobutylene‐b‐polystyrene)37 blends (2002)

Abstract The objective of these investigations was to increase the use temperature of novel star‐block polymers consisting of a crosslinked polydivinylbenzene (PDVB) core from which radiate multiple poly(isobutylene‐ b ‐polystyrene) (PIB‐ b ‐PSt) arms, abbreviated by PDVB(PIB‐ b ‐PSt) n . We achieved this objective by blending star‐blocks with poly(phenylene oxide) (PPO) that is miscible with PSt. Thus, various PPO/PDVB(PIB‐ b ‐PSt) n blends were prepared, and their thermal, mechanical, and processing properties were investigated. The hard‐phase glass‐transition temperature of the blends could be controlled by the amount (wt %) of PPO. The blends displayed superior retention of tensile strengths at high temperatures as compared to star blocks. The melt viscosities of blends with low weight percentages of PPO were lower than those of star blocks. © 2002 Wiley Periodicals, Inc. J Appl Polym Sci 86: 2866–2872, 2002
Neutral N^C^N terdentate luminescent Pt(ii) complexes: their synthesis, photophysical properties, and bio-imaging applications (2014)

An emerging field regarding N^C^N terdentate Pt(II) complexes is their application as luminescent labels for bio-imaging. In fact, phosphorescent Pt complexes possess many advantages such as a wide emission color tunability, a better stability towards photo- and chemical degradation, a very large Stokes shift, and long-lived luminescent excited states with lifetimes typically two to three orders of magnitude longer than those of classic organic fluorophores. Here, we describe the synthesis and photophysical characterization of three new neutral N^C^N terdentate cyclometallated Pt complexes as long-lived bio-imaging probes. The novel molecular probes bear hydrophilic (oligo-)ethyleneglycol chains of various lengths to increase their water solubility and bio-compatibility and to impart amphiphilic nature to the molecules. The complexes are characterized by a high cell permeability and a low cytotoxicity, with an internalization kinetics that depends on both the length of the ethyleneglycol chain and the ancillary ligand.
Differences in the mannose oligomer specificities of the closely related lectins from Galanthus nivalis and Zea maysstrongly determine their eventual anti-HIV activity (2011)

The markedly reduced anti-HIV activity of GNAmaize compared to GNA can be explained by the profound shift in glycan recognition and the disappearance of carbohydrate-binding sites in GNAmaize that have high affinity for mannose oligomers. These findings underscore the need for mannose oligomer recognition of therapeutics to be endowed with anti-HIV activity and that mannose, but not complex-type glycan binding of chemotherapeutics to gp120, may result in a pronounced neutralizing activity against the virus.
Modern management of vulvar cancer (2004)

The authors have concluded that the individualization of treatment for vulvar cancer patients has led to a decrease in morbidity but an increase in recurrences. The increase in recurrences does not appear to compromise prognosis, probably because of the lack of power, based on the low incidence of vulvar cancer. The sentinel lymph node procedure and primary radiotherapy are promising methods to reduce the morbidity of treatment but their safety needs to be studied in randomized trials.
Structure and properties of amorphous V2O5 (1991)

Abstract Pure non-stoichiometric amorphous vanadium pentoxide (V2O5) has been made by splat cooling from the melt. The vanadium coordination is analysed by infrared spectroscopy, X-ray absorption at the vanadium K edge (X-ray absorption near-edge structure and extended X-ray absorption fine structure) and 51V solid-state nuclear magnetic resonance. All these techniques show that V5+ ions exhibit both fourfold VO4 and fivefold VO5 coordination states. Electron spin resonance experiments show that unpaired electrons are localized on V4+ sites surrounded by five oxygen atoms as in crystalline V2O5. The amount of VO4 structural units in the amorphous oxide depends on experimental parameters such as temperature, quenching rate or water pressure. These observations could provide a clue to explain the controversies found in the literature concerning the vanadium coordination, the electrical conductivity and the chemical reactivity of V2O5-based amorphous compounds.
Large-Effective-Area Uncoupled Few-Mode Multi-Core Fiber (2012)

Characteristics of few-mode multi-core fiber (FM-MCF) were numerically analyzed and experimentally confirmed. Fabricated fibers supported two-mode transmission over C-band and L-band with the effective area of about 110 μm2 at 1550 nm. The crosstalks of the fibers were estimated to be smaller than -30 dB at 1550 nm after 100-km propagation.
A Complementary Electrochromic Device with Highly Improved Performance Based on Brick-Like Hydrated Tungsten Trioxide Film (2012)

Uniform and well adhesive nanostructured hydrated tungsten trioxide (3WO3 x H2O) films were grown on fluorine doped tin oxide (FTO) substrate via a facile and template-free crystal-seed-assisted hydrothermal method by addition of ammonium sulfate ((NH4)2SO4) and hydrogen peroxide (H2O2). X-ray diffraction (XRD) studies indicated that the films are of orthorhombic structure. Scanning electron microscopy (SEM) and high resolution transmission electron microscopy (HRTEM) analysis showed that the film was composed of brick-like nanostructures with a preferred growing direction along (002). The influence of seed layer, (NH4)2SO4 and H2O2 on the products were also studied. The film showed good cyclic stability, comparable switching speed and coloration efficiency (30.1 cm2 C(-1)). A complementary electrochromic device based on the film and Prussian blue depicted highly improved color contrast, coloration/bleaching response (1.8 and 3.7 s respectively) and coloration efficiency (164.6 cm2 C(-1)).
Factor IX inhibition and epitope localization of factor IX inhibitor antibodies in haemophilia B patients with anaphylactoid reactions (1997)

We describe the results of immunological studies, reaction kinetics and epitope localization of six inhibitor antibodies to factor IX (FIX) developed in severe haemophilia B patients. Three of the six patients had suffered recent anaphylactoid reactions to FIX concentrates, two others had in the past and one had none. All six inhibitors rapidly inactivated FIX activity in vitro, and the prominent immunoglobulin (IgG) subclass of the antibody was IgG4 when analysed with ELISA. Interestingly, we found an additional IgG1 component in the antibody samples from the patients who had recently experienced anaphylactoid reactions to FIX. When analysed with Western blotting in these three patients, the IgG4 antibody bound with enhanced affinity to the heavy chain or the light chain of FIX, and in two of the three the IgG1 antibody also bound strongly to the FIX heavy chain. The results suggest that the heavy chain of FIX might play a more significant role than the light chain in the pathogenesis of anaphylactoid reactions in haemophilia B patients with FIX inhibitors.