gebhart/patrepeval huggingface dataset:
Industry forum: IoT for real life part I (2016)

Summary form only given, as follows. The complete presentation was not made available for publication as part of the conference proceedings. If everybody tells the same story, then it's time to start new adventures! For a short time let the ARMy of boring "me-too" behind and discover a new realm of possibilities in the melting pot of digital and analog circuits. Experience a new form of "Inherent Artificial Intelligence", self-powered contactless "Smart-by-Nature" sensing circuits (beyond RFID & NFC), as well as new ideas for MEMS and Charge-Coupled Devices (CCD). How about a kind of "Alma-Mater-on-Chip", a vast cluster of "teachers" and "students", realized with "EPIC's nCP nanoCloudProcessors", to outsmart even Quantum computers? Wolf Richter talks & demonstrates (live on stage) what's possible today, to give you "Epic" ideas for tomorrow!
Rigid formation control with nonlinear passive actuation (2016)

This paper presents a distributed control law that locally forces a group of agents to self-organize into a rigid formation specified by a subset of interagent distances. The control law presented here is distributed as its execution requires each agent to only sense its relative positions with its neighbors, i.e. agents with whom they share a specified desired distance, and its own velocity. The paper extends [13], [17], and [18]. In [13] each agent is modeled as a single integrator. On the other hand, [17] assumes double integrator dynamics but requires that agents can also sense the velocities of their neighbors, doubling the communication/sensing overhead. In [18] the agent velocities are generated by the actuation signals through a Linear Time Invariant Positive Real dynamics. Double integrator dynamics are a special case of this. Unlike [17] no agent needs its neighbor's velocities. This paper on its parts relaxes the assumption of linear time invariance and instead assumes that the actuation to velocity dynamics of each agent is nonlinear but passive. We prove that the control law of [18] still guarantees local stability despite the presence of nonlinear actuation dynamics. We argue that, like [13], [17] and [18], no law for this problem can be globally stable.
A 56.1Gb/s NRZ Modulated 850nm VCSEL-Based Optical Link (2013)

We report a directly modulated 850nm VCSEL-based optical link operating at 56.1Gb/s (BER &lt; 1E-12). This is the highest modulation rate for a VCSEL-based link of any wavelength. An open eye is obtained at 60Gb/s.
Luteolin induces apoptosis in multidrug resistant cancer cells without affecting the drug transporter function: Involvement of cell line‐specific apoptotic mechanisms (2011)

Bioflavonoids are of considerable interest to human health as these serve as antioxidant and anticancer agents. Although epidemiological and experimental studies suggest that luteolin, a natural bioflavonoid, exhibits chemopreventive properties, its effectiveness as an antiproliferative agent against multidrug resistant (MDR) cancers is unclear. Thus, we assessed the antiproliferative effects of luteolin and associated molecular mechanisms using two MDR cancer cell lines that express high levels of P-glycoprotein and ABCG2. In this article, we demonstrate that luteolin induces apoptosis in P-glycoprotein- and ABCG2-expressing MDR cancer cells without affecting the transport functions of these drug transporters. Analysis of various proliferative signaling pathways indicated that luteolin-induced apoptosis involves reactive oxygen species generation, DNA damage, activation of ATR → Chk2 → p53 signaling pathway, inhibition of NF-kB signaling pathway, activation of p38 pathway and depletion of antiapoptotic proteins. Importantly, use of luteolin in these analyses also identified specific molecular characteristics of NCI-ADR/RES and MCF-7/Mito(R) cells that highlight their different tissue origins. These results suggest that luteolin possesses therapeutic potential to control the proliferation of MDR cancers without affecting the physiological function of drug transporters in the body tissues.
M Protein and Other Surface Proteins on Streptococci (2016)

Molecules on the surface of S. pyogenes range from a complex coiled coil modular structure, like the M protein, to conventional globular proteins and polysaccharides. All of the molecules on the bacterial surface have specifically evolved to enable survival in its human environment like the throat, blood, or skin. In particular, the M protein molecule has been finely tuned to allow the streptococcus to persist in infected tissues while skillfully avoiding human immune cells. As the first molecule on S. pyogenes to be completely sequenced, it is considered the archetypical surface molecule for these organisms and other Gram-positive bacteria; and as a result, in this chapter, it will be used as a comparator for the other surface proteins on streptococci.
Study protocol for a randomized, open-label, non-controlled Phase I/II Study to assess safety and immunogenicity of twice or three times dosing of intramuscular COVID-19 DNA vaccine in healthy adults (2021)

There is currently an outbreak of respiratory disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and many vaccines have been rapidly developed using different technologies. We have challenged to develop DNA vaccines for SARS-CoV-2. After the basic and preclinical experiments, AnGes, Inc. conducted a randomized, open-label, non-controlled Phase I/II Study to assess safety and immunogenicity of intramuscular DNA vaccine (AG0302-COVID19) in Osaka University Hospital. Thirty healthy volunteers, male or female, aged 20–65, will be randomized to one of the following three groups, 1) 2.0 mg of AG0302-COVID19 twice at 2-week intervals, 2) 2.0 mg of AG0302-COVID19 twice at 4-week intervals, 3) 2.0 mg of AG0302-COVID19 three times at 2-week intervals. This study will assess the safety and immunogenicity of AG0302-COVID19. The primary endpoint about the safety and tolerability has been assessed by the incidence of treatment emergent adverse events from week 1 through week 9, and frequency and severity of each adverse event, including solicited local and systemic adverse events through 8 weeks after the first vaccination. The immunogenicity has been also assessed by the change in geometric mean titer (GMT) of serum anti-SARS-CoV-2 Spike glycoprotein specific antibody. This study has been registered at the ClinicalTrials.gov.as NCT04527081.
The antischistosomal potential of GSK-J4, an H3K27 demethylase inhibitor: insights from molecular modeling, transcriptomics and in vitro assays (2020)

GSK-J4 presents promising potential for antischistosomal control; however, the underlying mechanisms warrant further investigation.
Pharmacokinetics, Dose Proportionality, and Tolerability of Gadobutrol after Single Intravenous Injection in Healthy Volunteers (1994)

Single intravenous administration of gadobutrol was well tolerated up to the dose level of 0.5 mmol/kg body weight. These factors suggest that gadobutrol will be a safe magnetic resonance imaging contrast agent.
ChemInform Abstract: Synthesis of 7‐Methoxybenzolactam‐V8 Using a Diastereoselective Strecker Synthesis. (2001)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Structural analysis of the alternating copolymer poly(chloroacrylonitrile-alt-cyclohexadiene) (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural analysis of the alternating copolymer poly(chloroacrylonitrile-alt-cyclohexadiene)V. Panchalingam and John R. ReynoldsCite this: Macromolecules 1988, 21, 4, 960–967Publication Date (Print):April 1, 1988Publication History Published online1 May 2002Published inissue 1 April 1988https://pubs.acs.org/doi/10.1021/ma00182a020https://doi.org/10.1021/ma00182a020research-articleACS PublicationsRequest reuse permissionsArticle Views75Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Three dimensional kinematics of the thoracolumbar spine as quantified by a novel in vivo/in vitro active/passive robotic simulator (2011)

Low back pain is one of the leading causes of missed work. Surgical intervention is an option to those who have failed conservative therapy. The current gold standard of surgical procedures is bony fusion. Long term follow up of fusion patients has identified adjacent level disease as a complication. New motion preserving technologies aim to eliminate harmful effects on adjacent levels but have not been confirmed with long term clinical trials. In vitro testing provides repeatability for relative comparison between treatments, but the clinical relevance remains questionable without in vivo loads and motions. We have developed a novel in vivo/in vitro method using active motion to characterize the motion of the thoracolumbar spine using a robotic simulator. Preliminary results indicate a reduction in motion at the operative and super-adjacent level while motion is increased at all other levels. This may be compensation for the reduced motions at the operative and adjacent level.
ChemInform Abstract: A New Synthesis of 1,4‐Thiazin‐3‐ones by a Novel Rearrangement of 1,4‐ Oxathiins. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Tuning magnetic, electronic, and optical properties of Mn-doped NiCr2O4 via microwave method (2021)

The main aim of the paper to the synthesis of Mn (x)-doped NiCr2O4 nanoparticles by varying Mn content (x = 0.00%, 0.01%, 0.02%, and 0.03%) by microwave method for correlating the effect of NiCr2O4 on structural, optical, and magnetic properties of the materials. Understanding the optical, magnetic, and structural properties of huge reservoir factors has essential applications in various aspects of materials science. Our study is to relate the reduction of grain size of Mn content in NiCr2O4 host material. The XRD results revealed that there was an apparent decrease in the characteristic peaks of Mn in the MnNiCr2O4 nanostructure. Particularly, the peak position of (2 2 0) and (3 1 1) planes was decreased. This decrease in peak position is attributed to the creation of defects or disorders due to the Mn ions in the chromite lattice structure. This inter-site Mn cation migration is responsible for the breaking of long-range cation order and the introduction of defects at both the T-site and O-sublattices site simultaneously.
Aerothermal Performance of a Nozzle Vane Cascade With a Generic Nonuniform Inlet Flow Condition—Part II: Influence of Purge and Film Cooling Injection (2017)

In the present paper, the influence of the presence of an inlet flow nonuniformity on the aerodynamic and thermal performance of a film cooled linear nozzle vane cascade is fully assessed. Tests have been carried out with platform cooling, with coolant ejected through a slot located upstream of the leading edge. Cooling air is also ejected through a row of cylindrical holes located upstream of the slot, simulating a combustor cooling system. An obstruction was installed upstream of the cascade at variable tangential and axial position to generate a flow nonuniformity. The cascade was tested at a high inlet turbulence intensity level (Tu1 = 9%) and at a constant inlet Mach number of 0.12 and nominal cooling condition. Aerothermal characterization of vane platform was obtained through five-hole probe and end wall adiabatic film cooling effectiveness measurements. Results show a relevant negative impact of inlet flow nonuniformity on the cooled cascade aerodynamic and thermal performance. Higher film cooling effectiveness and lower aerodynamic losses are obtained when the inlet flow nonuniformity is located at midpitch, while lower effectiveness and higher losses are obtained when it is aligned to the vane leading edge. Moving the nonuniformity axially or changing its blockage only marginally influences the platform thermal protection.
Design Metrics and the Adaptation of Web-Page Content Chunks for PDAs (2017)

The majority of web-pages are unsuitable for viewing on PDAs, WAP phones and similar devices without first being adapted. However, little empirical work has been done on what actually constitutes a good PDA or WAP web-page. This paper ranks a number of PDA web-pages from different categories empirically and correlates the result against the design metrics present. The findings are then compared against a similar set of experiments for PC web-pages. The results of this comparison suggest that, as well as omitting, summarizing and converting individual multimedia objects in the web-page to a less resource intensive form, the design metrics need to be changed during adaptation to enhance the presentation of web-content on non-PC devices. The paper concludes by investigating the effect of applying some suitable changes to the design metrics on web=page content chunks, which form the basic units in automatic content adaptation systems.
Caracterización del chorizo verde mexicano durante el procesado y conservación a distintas temperaturas: Aminas biógenas (2016)

El objetivo de este trabajo fue la caracterizacion fisico-quimica y microbiologica del chorizo verde mexicano durante su procesado y conservacion a dos temperaturas distintas: en refrigeracion (4 °C) y a temperatura ambiente (20 °C). La composicion del chorizo (humedad 54.80%, cenizas 4.80%, grasa 15.10%, proteina 16.89% y carbohidratos 8.60%) y su valor energetico (237.06 Kcal/g) dependio de los ingredientes empleados en su elaboracion y del procesado. Durante el procesado se observo una perdida de peso del 43%, junto con una disminucion (p 8 Log ufc/g), mientras que se observo un descenso en las enterobacterias hasta niveles <3 Log ufc/g. El contendido en aminas biogenas aumento durante el procesado. Los recuentos microbianos y el pH se mantuvieron en general sin cambios significativos durante el almacenamiento a las dos temperaturas, excepto las enterobacterias que descendieron hasta niveles de <1 Log ufc/g a los 10 dias de almacenamiento. El color y la textura se vieron afectados (p<0.05) en las muestras almacenadas a 20 °C. Estas muestras durante los 10 dias de almacenamiento tambien presentaron una perdida de peso del 61.43%. La conservacion a 20 oC y el tiempo de almacenamiento influyeron significativamente en la formacion de aminas biogenas, observandose un incremento en sus niveles a los 10 dias de conservacion.
Non-linear vector-perturbation precoding for multi-user downlink under quantized CSI (2015)

This paper focuses on the design of vector perturbation (VP) precoding for multi-user multiple-input singleoutput downlink transmission under quantized channel state information. Each receiver decomposes its downlink channel vector in forms of channel direction information (CDI) and channel magnitude information (CMI) for feedback to the transmitter. Under quantized CDI and quantization error statistics, closed-form expressions to the mean-squared-error (MSE) between channel input and output when (i) perfect CMI available to the transmitter and (ii) only CMI statistics known at the transmitter, are derived. We then propose a unified approach to design the MSE minimization based VP precoders. Bit error rate simulation results indicate that the proposed VP precoder designs are less sensitive to quantization errors and CMI availability helps to improve the performance.
Improving Slab Excitation by Parallel Transmission (2012)

Transmit SENSE is typically applied to improve spatially selective RF pulses in two or three dimensions. This study investigates the application of Transmit SENSE to one-dimensional RF pulses. For these RF pulses, Transmit SENSE is applicable in case of large B1 variations across the slice or slab to be excited. Typically, such large B1 variations are found across the slabs excited in 3D volume imaging orin the framework of the REgional Saturation Technique (REST). 1D Transmit SENSE can improve the excitation slab profile, and particularly can result in a significant reduction of RF power and the relatedspecific absorption rate (SAR). Since the involved RF pulses have the same duration as standard slice-selection pulses, they can easilybe incorporated in standard sequences without changing sequence timing. The approach was tested using synthetic and realistic coil sensitivity profiles.
Comparison of Risk Factors for Pediatric Kidney Stone Formation: The Effects of Sex (2019)

<b>Background:</b> Urinary stones are affecting more children, and pediatric stone formers have unique pathophysiology compared to adults. While adult stone formers are most frequently male, children have an age dependent sex prevalence. Under 10 years, a majority of stone formers are boys; adolescent stone formers are mostly female. Previous adult studies have shown that stone composition is influenced by the sex and age of the stone former. Thus, we hypothesize that female and male stone forming children will also have sex and age specific stone phenotypes. <b>Methods:</b> Retrospective chart review of a large pediatric center's stone forming children 6/1/2009 to 6/1/2016. Patients were identified by ICD 9 codes: N20, N20.1, and N20.9. Charts were reviewed for radiographic evidence of stones or documented visualized stone passage. <b>Results:</b> One hundred and thirty six subjects: 54 males and 82 females. Females were older, median age 14 years [interquartile range (IQR): 11, 15] vs. males' median age 12 years (IQR: 11, 14) (<i>p</i> < 0.01). Females had lower height <i>z</i>-scores, median 0.2 (IQR: -0.8, 0.8) vs. males' median 0.8 (IQR: -0.2, 1.8) (<i>p</i> < 0.01). Presenting symptoms were similar except flank pain affecting 39% of females vs. 22% of males (<i>p</i> = 0.04). Leukocyte esterase was positive in more females than males (33 vs. 4%) (<i>p</i> < 0.001). Males had a higher BUN/Cr ratio, mean ± standard deviation of 19.8 ± 6.3 vs. 16.6 ± 6.5 in females (<i>p</i> = 0.01). Glomerular hyperfiltration was present in 9% of patients while 35% of patients had estimated glomerular filtration rate (eGFR) < 90 ml/min/1.73 m<sup>2</sup>. Treatment strategies and clinical course were similar except females were told to increase dietary citrate more frequently than males (21 vs. 4%) (<i>p</i> < 0.01). <b>Conclusion:</b> We have provided a novel analysis and demonstrated that low height <i>z</i>-score and pyuria are more common in female stone formers. We have also shown that 9% of pediatric stone formers have labs consistent with hyperfiltration. Whether high protein intake and/or chronic dehydration are associated with hyperfiltration and long-term renal function in children with kidney stones will be an area for future research.
On-chip self-calibrating communication techniques robust to electrical parameter variations (2004)

Dynamic self-calibration holds the promise of overcoming conservative worst-case design techniques needed to combat deep-submicron process and operating variations. We propose an on chip point-to-point interconnect scheme characterized by self-calibration that can operate dynamically to achieve the best energy/performance trade-off.
Long-Duration Ventricular Fibrillation Exhibits 2 Distinct Organized States (2013)

After 3 minutes, VF exhibits 2 highly organized endocardial activation patterns 96% of the time, one potentially arising focally in the Purkinje system that was prevented with a K(ATP) channel opener but not a calcium channel blocker and the other potentially arising from a stable re-entrant circuit near the apical left ventricular endocardium.
Effects of Mechanical Stretch on Collagen and Cross-Linking in Engineered Blood Vessels (2009)

It has been shown that mechanical stimulation affects the physical properties of multiple types of engineered tissues. However, the optimum regimen for applying cyclic radial stretch to engineered arteries is not well understood. To this end, the effect of mechanical stretch on the development of engineered blood vessels was analyzed in constructs grown from porcine vascular smooth muscle cells. Cyclic radial distension was applied during vessel culture at three rates: 0 beats per minute (bpm), 90 bpm, and 165 bpm. At the end of the 7-week culture period, harvested vessels were analyzed with respect to physical characteristics. Importantly, mechanical stretch at 165 bpm resulted in a significant increase in rupture strength in engineered constructs over nonstretched controls. Stress-strain data and maximal elastic moduli from vessels grown at the three stretch rates indicate enhanced physical properties with increasing pulse rate. In order to investigate the role of collagen cross-linking in the improved mechanical characteristics, collagen cross-link density was quantified by HPLC. Vessels grown with mechanical stretch had somewhat more collagen and higher burst pressures than nonpulsed control vessels. Pulsation did not increase collagen cross-link density. Thus, increased wall thickness and somewhat elevated collagen concentrations, but not collagen cross-link density, appeared to be responsible for increased burst strength.
Hybrid Radio/Free-Space Optical Design for Next Generation Backhaul\n Systems (2015)

The deluge of date rate in today's networks imposes a cost burden on the\nbackhaul network design. Developing cost efficient backhaul solutions becomes\nan exciting, yet challenging, problem. Traditional technologies for backhaul\nnetworks include either radio-frequency backhauls (RF) or optical fibers (OF).\nWhile RF is a cost-effective solution as compared to OF, it supports lower data\nrate requirements. Another promising backhaul solution is the free-space optics\n(FSO) as it offers both a high data rate and a relatively low cost. FSO,\nhowever, is sensitive to nature conditions, e.g., rain, fog, line-of-sight.\nThis paper combines both RF and FSO advantages and proposes a hybrid RF/FSO\nbackhaul solution. It considers the problem of minimizing the cost of the\nbackhaul network by choosing either OF or hybrid RF/FSO backhaul links between\nthe base-stations (BS) so as to satisfy data rate, connectivity, and\nreliability constraints. It shows that under a specified realistic assumption\nabout the cost of OF and hybrid RF/FSO links, the problem is equivalent to a\nmaximum weight clique problem, which can be solved with moderate complexity.\nSimulation results show that the proposed solution shows a close-to-optimal\nperformance, especially for practical prices of the hybrid RF/FSO links.\n