gebhart/patrepeval huggingface dataset:
Correction to “Synthetic Phosphorus Metabolic Pathway for Biosafety and Contamination Management of Cyanobacterial Cultivation” (2021)

ADVERTISEMENT RETURN TO ISSUEPREVCorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "Synthetic Phosphorus Metabolic Pathway for Biosafety and Contamination Management of Cyanobacterial Cultivation"Kei MotomuraKei MotomuraMore by Kei Motomura, Kosuke SanoKosuke SanoMore by Kosuke Sano, Satoru WatanabeSatoru WatanabeMore by Satoru Watanabe, Akihiro KanbaraAkihiro KanbaraMore by Akihiro Kanbara, Gamal Nasser Abdel-HadyGamal Nasser Abdel-HadyMore by Gamal Nasser Abdel-Hady, Takeshi IkedaTakeshi IkedaMore by Takeshi Ikeda, Takenori IshidaTakenori IshidaMore by Takenori Ishida, Hisakage FunabashiHisakage FunabashiMore by Hisakage Funabashihttps://orcid.org/0000-0003-2330-1503, Akio KurodaAkio KurodaMore by Akio Kuroda, and Ryuichi Hirota*Ryuichi Hirota*Email: [email protected]More by Ryuichi Hirotahttps://orcid.org/0000-0003-3959-5892Cite this: ACS Synth. Biol. 2021, 10, 7, 1797Publication Date (Web):June 21, 2021Publication History Received24 May 2021Published online21 June 2021Published inissue 16 July 2021https://pubs.acs.org/doi/10.1021/acssynbio.1c00237https://doi.org/10.1021/acssynbio.1c00237correctionACS PublicationsCopyright © 2021 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views665Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (498 KB) Get e-AlertscloseSUBJECTS:Contamination,Order,Phosphorus Get e-Alerts
Characterization of an Inhibitory Seric Factor From Tuberculosis Anergic Patients That Acts on non-Adherent PPD Reactive Cells (1995)

Non-adherent cells from PPD+ tuberculosis patients (TBP PPD+) and from healthy individuals treated with whole tuberculosis anergic immune sera or with its protein A-Sepharose IgG fraction, or with sera fraction separated by PPD-Sepharose chromatography, were submitted to immunofluorescence assays. Anti-human IgG or IgM FITC-conjugate were used to reveal the assays, and results were expressed by a fluorescence percentage or fluorescence index. The presence of IgG over the surface of PPD+ non-adherent cells was detected. High fluorescence percentages were observed only in those PPD+ cells treated with whole anergic serum or with its IgG fraction. Positive fluorescence index values were obtained only in those PPD+ cells treated with anergic serum, meanwhile fluorescence index was always negative when non-bound fractions from PPD-Sepharose were used. Results suggest that non-adherent population are the cell targets for the serum inhibitory factor, which previously has been detected to inhibit antigen response in PPD reactive cells and, point out the specific behavior of this factor, since it was eliminate by PPD-Sepharose chromatography. The IgG nature of the factor was demonstrated by SDS-PAGE and immunoelectrophoresis.
Numerical Prediction of Ultimate Strength of RC Beams and Slabs with a Patch by p-Version Nonlinear Finite Element Modeling and Experimental Verification (2004)

A new finite element model will be presented to analyze the nonlinear behavior of RC beams and slabs strengthened by a patch repair. The numerical approach is based on the p-version degenerate shell element including theory of anisotropic laminated composites, theory of materially and geometrically nonlinear plates. In the nonlinear formulation of this model, the total Lagrangian formulation is adopted with large deflections and moderate rotations being accounted for in the sense of von Karman hypothesis. The material model is based on hardening rule, crushing condition, plate-end debonding strength model and so on. The Gauss-Lobatto numerical quadrature is applied to calculate the stresses at the nodal points instead of Gauss points. The validity of the proposed p-version nonlinear finite element model is demonstrated through the load-deflection curves, the ultimate loads, and the failure modes of RC beams or slabs bonded with steel plates or FRP plates compared with available result of experiment and other numerical methods.
Current-voltage raw data and spectra for thiophene polymer characterization and sensing responses (2017)

This dataset is backup information for the publication whose abstract is reproduced here. NO2-responsive polymer-based organic field-effect transistors (OFETs) are described and room-temperature detection with high sensitivity entirely from the semiconductor was achieved. Two thiophene polymers, poly(bisdodecylquaterthiophene) and poly(bisdodecylthioquaterthiophene) (PQT12 and PQTS12, respectively), were used as active layers to detect a concentration at least as low as 1 ppm NO2. The proportional on-current change of OFETs using these polymers reached over 400% for PQTS12, which is among the highest sensitivities reported for an NO2-responsive device based on an organic semiconducting film. From measurements of cyclic voltammetry and the electronic characteristics, we found that the introduction of sulfurs into the side chains induces traps in films of the PQTS12 and also decreases domain sizes, both of which could contribute to the higher sensitivity of PQTS12 to NO2 gas compared to PQT12. The ratio of responses of PQTS12 and PQT12 is higher for exposures to lower concentrations, making this parameter a means of distinguishing responses to low concentrations for extended times from exposures to high concentrations from shorter times. The responses to nonoxidizing vapors were much lower indicating good selectivity to NO2 of two polymers. This work demonstrates the capability of increasing selectivity and calibration of OFET sensors by modulating redox and aggregation properties of polymer semiconductors.
Improving the long-term stability of PBDTTPD polymer solar cells through material purification aimed at removing organic impurities (2013)

While bulk heterojunction (BHJ) solar cells fabricated from high Mn PBDTTPD achieve power conversion efficiencies (PCE) as high as 7.3%, the short-circuit current density (JSC) of these devices can drop by 20% after seven days of storage in the dark and under inert conditions. This degradation is characterized by the appearance of S-shape features in the reverse bias region of current–voltage (J–V) curves that increase in amplitude over time. Conversely, BHJ solar cells fabricated from low Mn PBDTTPD do not develop S-shaped J–V curves. However, S-shapes identical to those observed in high Mn PBDTTPD solar cells can be induced in low Mn devices through intentional contamination with the TPD monomer. Furthermore, when high Mn PBDTTPD is purified via size exclusion chromatography (SEC) to reduce the content of low molecular weight species, the JSC of polymer devices is significantly more stable over time. After 111 days of storage in the dark under inert conditions, the J–V curves do not develop S-shapes and the JSC degrades by only 6%. The S-shape degradation feature, symptomatic of low device lifetimes, appears to be linked to the presence of low molecular weight contaminants, which may be trapped within samples of high Mn polymer that have not been purified by SEC. Although these impurities do not affect initial device PCE, they significantly reduce device lifetime, and solar cell stability is improved by increasing the purity of the polymer materials.
Lysosome‐Associated Membrane Protein 3 Induces Lysosome‐Dependent Cell Death by Impairing Autophagic Caspase 8 Degradation in the Salivary Glands of Individuals With Sjögren's Disease (2023)

LAMP3 overexpression induced lysosomal dysfunction, resulting in lysosome-dependent cell death via impaired autophagic caspase 8 degradation, and restoring lysosomal function using GLP-1R agonists could prevent this. These findings suggested that LAMP3-induced lysosomal dysfunction is central to disease development and is a target for therapeutic intervention in SjD.
Charge transfer state emission dynamics in blue-emitting functionalized silicon nanocrystals (2015)

We explore the dynamics of blue emission from dodecylamine and ammonia functionalized silicon nanocrystals (Si NCs) with average diameters of ∼3 and ∼6 nm using time-resolved photoluminescence (TRPL) spectroscopy. The Si NCs exhibit nanosecond PL decay dynamics that is independent of NC size and uniform across the emission spectrum. The TRPL measurements reveal complete quenching of core state emission by a charge transfer state that is responsible for the blue PL with a radiative recombination rate of ∼5 × 10(7) s(-1). A detailed picture of the charge transfer state emission dynamics in these functionalized Si NCs is proposed.
Prenatal exposure to tobacco smoke leads to increased mitochondrial DNA content in umbilical cord serum associated to reduced gestational age (2016)

We investigated if prenatal exposures to tobacco smoke lead to changes in mitochondrial DNA content (mtDNA) in cord serum and adversely affect newborns' health. Umbilical cord serum cotinine levels were used to determine in utero exposure to smoking. Cord serum mtDNA was measured by quantitative polymerase chain reaction analysis of the genes coding for cytochrome c oxidase1 (MT-CO1) and cytochrome c oxidase2 (MT-CO2). Log transformed levels of mtDNA coding for MT-CO1 and MT-CO2 were significantly higher among infants of active smokers with higher serum level of cotinine (p < 0.05) and inversely associated with gestational age (p = 0.08; p = 0.02). Structural equation modeling results confirmed a positive association between cotinine and MT-CO1 and2 (p < 0.01) and inverse associations with gestational age (p = 0.02) and IGF-1 (p < 0.01). We identified a dose-dependent increase in the level of MT-CO1 and MT-CO2 associated to increased cord serum cotinine and decreased gestational age.
Transition Management of Microgrids With High Penetration of Renewable Energy (2013)

Microgrids are receiving attention due to the increasing need to integrate distributed generations and to ensure power quality and to provide energy surety to critical loads. Some of the main topics concerning microgrids are transients and stability concerns during transitions including intentional and unintentional islanding and reconnection. In this paper, the standard IEEE 34 bus distribution feeder is adapted and managed as a microgrid by adding distributed generations and load profiles. Supervisory power managements have been defined to manage the transitions and to minimize the transients on voltage and frequency. Detailed analyses for islanding, reconnection, and black start are presented for various conditions. The proposed control techniques accept inputs from local measurements and supervisory controls in order to manage the system voltage and frequency. An experimental system has been built which includes three 250 kW inverters emulating natural gas generator, energy storage, and renewable source. The simulation and experimental results are provided which verifies the analytical presentation of the hardware and control algorithms.
Frame Mapping and Motion Constraint Effects on Task Performance in Robotic Endoscopic Surgery (1999)

Abstract This paper presents the implementation and evaluation of a minimally invasive surgical system whereby a surgeon can maintain as natural a spatio-motor mapping as possible using a 4 DOF constrained slave robot. One way to achieve this interface is to interpose a robotic system between surgeon and patient which will act as a translator between the 6 degree-of-freedom open surgery-like motions of the surgeon and corresponding endoscopic motions within the patient. Our goal was to find the interface that was easiest to learn. We investigated the effects of different master-slave mappings (screen-mapped versus instrument-mapped) and master dexterities (6DOF versus 4 DOF) by means of performance measures noted on simple surgical tasks. This interface has been found to allow motions very similar to those used in natural prehension and open surgery. The particular combination of instrument-based master-slave mapping and 4DOF master has been found to be especially advantageous.
Segmentation algorithms for abdominal computerized tomography scans (2005)

Two approaches to organ detection in ab dominal computerized tomography scans, one local and one global, have been developed. The first involves a boundary-delineating algorithm which operates homogeneously on entire images and coordinates the use of multiple local criteria for advanced edge detection. The second involves an iterative, adaptive boundary-delineating algorithm suitable for single organ detection and amenable to the incorporation of organ-specific knowledge. Regional results of the first (global) algorithm can initialize the second (local) algorithm. Algorithms were tested on mathematical phantoms prior to application on clinical patient data.
A case of Sakoda complex with medial cleft lip and palate (2013)

Sakoda complex is as a distinctive disease entity characterized by sphenoethmoidal meningoencephalocele, agenesis of the corpus callosum, and cleft lip, cleft palate, or both. The etiology remains unclear. However, this characteristic congenital malformation complex may be explained by embryological restriction of the cephalic neural crest and improper separation between the neurectoderm and the surface ectoderm after neural tube formation. We describe a patient with anomalies consistent with the Sakoda complex. The patient's extraoral findings included bilateral orbital proptosis, left exotropia, a right accessory auricle, and incomplete medial cleft lip, and intraoral findings included medial cleft jaw and upper labial frenum. MR imaging of the brain showed enlargement of the posterior horns and an Azygos-type anterior cerebral artery. He had life-threatening symptoms such as obstructive respiratory problems, but showed improvement in accordance with growth. About 7 months after birth, we performed an operation to close the cleft lip. During and after the operation, the infant had transient abnormalities of thermoregulation due to a pituitary disorder, but the condition was not so serious. In patients with a good prognosis, lip plasty and palatoplasty are necessary not only to improve aesthetic problems and feeding disorders, but also to protect the meningoencephalocele.
Production and Characterization of Protective Human Antibodies against Shiga Toxin 1 (2002)

Hemolytic-uremic syndrome (HUS) is a serious complication which is predominantly associated in children with infection by Shiga toxin-producing Escherichia coli (STEC). By using HuMAb-Mouse (Medarex) animals, human monoclonal antibodies (Hu-MAbs) were developed against Shiga toxin 1 (Stx1) for passive immunotherapy of HUS. Ten stable hybridomas comprised of fully human heavy- and light-chain immunoglobulin elements and secreting Stx1-specific Hu-MAbs (seven immunoglobulin M(kappa)() [IgM(kappa)] elements [one specific for the A subunit and six specific for the B subunit] and three IgG1(kappa) elements specific for subunit B) were isolated. Two IgM(kappa) Hu-MAbs (2D9 and 15G9) and three IgG1(kappa) Hu-MAbs (5A4, 10F4, and 15G2), all specific for subunit B, demonstrated marked neutralization of Stx1 in vitro and significant prolongation of survival in a murine model of Stx1 toxicosis.
Correction. Inter- and Intramolecular Insertion of Rhenium into Carbon-Hydrogen Bonds (1987)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCorrection. Inter- and Intramolecular Insertion of Rhenium into Carbon-Hydrogen BondsTimothy Wenzel and Robert BergmanCite this: J. Am. Chem. Soc. 1987, 109, 16, 5052Publication Date (Print):August 1, 1987Publication History Published online10 May 2004Published inissue 1 August 1987https://pubs.acs.org/doi/10.1021/ja00250a601https://doi.org/10.1021/ja00250a601research-articleACS PublicationsRequest reuse permissionsArticle Views37Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Development of Tethered Flying Robots with PAUT Capabilities for C-Scan and In-Service Inspection Mini-Crawler/Uav: Marsupial Robotic Approach (2022)

Abstract Avestec has successfully developed proprietary contact-based flying robots (SKYRON™) for ultrasonic (UT) A scan measurement of metallic surfaces. The technology has been successfully validated with many asset owners in onshore and offshore industrial campaigns. Although the flying contact-based robot can easily access most asset surfaces to perform inspections, it has some limitations when it comes to challenging and dense spaces. Such shortcoming is exasperated specially for pipe inspection in offshore environments. Pipes are usually located in the vicinity of one another or in close proximity to walls or other structures, which makes it practically impossible for an unmanned aerial vehicle (UAV) to reach to every side of the pipe and carry out circumferential (3/6/9/12) measurement as needed. In order to enhance the advantages of contact-based aerial robots and overcome the aforementioned limitations, a marsupial robotic methodology has been followed by means of combining the proprietary contact-based UAV and a custom omni-directional mini crawler in a collaborative robotics fashion. An advanced marsupial connection between the two robots both in terms of mechanical (e.g., carrier/passenger roles) and control mechanism (e.g. master/slave roles) and versatility of the task deliveries can potentially introduce a lot of advantages over a single flying robot for asset inspection. In addition, Phased Array Ultrasonic (PAUT) sensory package has been integrated into the marsupial robot to expand NDT capabilities for inspection including thickness measurements, corrosion mapping, defect detection (e.g. such as cracks, voids, and pits caused by corrosion), weld inspection and many more.
Mammalian Cell Proliferation Requires Noncatalytic Functions of O-GlcNAc Transferase (2020)

Abstract O-GlcNAc transferase (OGT), found in the nucleus and cytoplasm of all mammalian cell types, is essential for cell proliferation. Why OGT is required for cell growth is not known. OGT performs two enzymatic reactions in the same active site. In one, it glycosylates thousands of different proteins, and in the other, it proteolytically cleaves another essential protein involved in gene expression. Deconvoluting OGT’s myriad cellular roles has been challenging because genetic deletion is lethal; complementation methods have not been established. Here, we developed approaches to replace endogenous OGT with separation-of-function variants to investigate the importance of OGT’s enzymatic activities for cell viability. Using genetic complementation, we found that OGT’s glycosyltransferase function is required for cell growth but its protease function is dispensable. We next used complementation to construct a cell line with degron-tagged wild-type OGT. When OGT was degraded to very low levels, cells stopped proliferating but remained viable. Adding back catalytically-inactive OGT rescued growth. Therefore, OGT has an essential noncatalytic role that is necessary for cell proliferation. By developing a method to quantify how OGT’s catalytic and noncatalytic activities affect protein abundance, we found that OGT’s noncatalytic functions often affect different proteins from its catalytic functions. Proteins involved in oxidative phosphorylation and the actin cytoskeleton were especially impacted by the noncatalytic functions. We conclude that OGT integrates both catalytic and noncatalytic functions to control cell physiology. Significance Mammalian cells contain only one glycosyltransferase, OGT, that operates in the nucleus and cytoplasm rather than the secretory pathway. OGT is required for cell proliferation, but a basic unanswered question is what OGT functions are essential. This question is challenging to address because OGT has thousands of glycosylation substrates, two different enzymatic activities, and a large number of binding partners. Here, by establishing genetic tools to replace endogenous OGT with variants that preserve only a subset of its activities, we show that only a low level of glycosylation activity is required to maintain cell viability; however, cell proliferation requires noncatalytic OGT function(s). The ability to replace OGT with variants provides a path to identifying its essential substrates and binding partners.
Pilot-tone-based self-homodyne detection using optical nonlinear wave mixing (2017)

An all-optical pilot-tone-based self-homodyne detection scheme using nonlinear wave mixing is experimentally demonstrated. Two scenarios are investigated using (1) multiple wavelength-division-multiplexed channels with sufficient power of the pilot tones and (2) a single channel with a low-power pilot tone. The eye diagram and bit error rate of the system are studied by tuning various parameters such as pump power, relative phase, and pilot-to-signal ratio.
POSTERIOR RETINAL BREAKS AS A CAUSE OF VITREOUS HEMORRHAGE IN DIABETES (2008)

The differential diagnosis for vitreous hemorrhage in diabetic patients should include posterior retinal breaks, particularly in the absence of proliferative disease. These breaks are paravascular, are located in areas of retinal ischemia, and may involve avulsed bridging vessels. We suggest treatment with barrier rather than panretinal photocoagulation.