gebhart/patrepeval huggingface dataset:
Investigation of the Electrical Properties of Tantalum-Ruthenium Dioxide as a Diffusion Barrier for High Dielectric Capacitors (2000)

The effects of addition on the electrical properties of a diffusion barrier for capacitor bottom electrodes were investigated as a function of the composition ratio of and contact size, at a temperature range of 650–800°C in air. When the Ta film was deposited without addition, it exhibited a higher total resistance and a nonohmic behavior with increasing annealing temperature, originating from the formation of a nonconductive phase by reaction between the Ta film and the external ambient oxygen after annealing. For both the and the contact system, no other phase, such as , Pt‐silicides, and Pt‐Ta compounds, was observed except for the formation of a conductive crystalline phase after annealing, followed by the prevention of surface oxidation of the diffusion barrier itself as well as the retention of the bottom electrode structure up to 800°C. This resulted in a lower total resistance and an ohmic characteristic. Therefore, it can be concluded that ohmic behavior does not depend on contact size for both contact systems and all compositions in this study. © 2000 The Electrochemical Society. All rights reserved.
Toward an Inoperative Civilization (2014)

The unapologetic re-emergence in recent years of the term “civilization” in American foreign policy circles and best-selling books merits closer scrutiny. This essay examines two different views of civilization that have attracted recent critical attention. The first is a rather militant defense of civilization. In this view, civilized nations see themselves as exempt from the very laws and principles on which they are founded, thereby enabling them, in the name of the civilizing (or pro-democracy) mission, to exert force or violence on those others who threaten civilization (also known as “barbarians,” “savages,” “terrorists,” or “enemies of democracy”) and who also happen to be, conveniently, in a state of exception from civilization and can therefore be subjected to violence. The second model of civilization reflects a certain liberal optimism. Rather than precipitating “clashes,” civilization, in this view, does not confer exceptionality on a nation or allow for the exploitation of vulnerable others; instead, a civilization should concern itself with the expansion and fusion of horizons and the need to engage in a dialogue with other cultures and societies without exception or exclusion. In describing these two views, I note the violence inherent in the model of civilization as an exception and the difficulties that confront the dialogical model. Drawing on the work of Jean-Luc Nancy and Giorgio Agamben, as well as J. M. Coetzee’s novel Waiting for the Barbarians , I conclude with some reflections on the need to revise our current views of civilization by sketching an alternative possibility of an inoperative civilization.
You Must Have Clicked on this Ad by Mistake! Data-Driven Identification of Accidental Clicks on Mobile Ads with Applications to Advertiser Cost Discounting and Click-Through Rate Prediction (2018)

In the cost per click (CPC) pricing model, an advertiser pays an ad network only when a user clicks on an ad; in turn, the ad network gives a share of that revenue to the publisher where the ad was impressed. Still, advertisers may be unsatisfied with ad networks charging them for "valueless" clicks, or so-called accidental clicks. [...] Charging advertisers for such clicks is detrimental in the long term as the advertiser may decide to run their campaigns on other ad networks. In addition, machine-learned click models trained to predict which ad will bring the highest revenue may overestimate an ad click-through rate, and as a consequence negatively impacting revenue for both the ad network and the publisher. In this work, we propose a data-driven method to detect accidental clicks from the perspective of the ad network. We collect observations of time spent by users on a large set of ad landing pages - i.e., dwell time. We notice that the majority of per-ad distributions of dwell time fit to a mixture of distributions, where each component may correspond to a particular type of clicks, the first one being accidental. We then estimate dwell time thresholds of accidental clicks from that component. Using our method to identify accidental clicks, we then propose a technique that smoothly discounts the advertiser's cost of accidental clicks at billing time. Experiments conducted on a large dataset of ads served on Yahoo mobile apps confirm that our thresholds are stable over time, and revenue loss in the short term is marginal. We also compare the performance of an existing machine-learned click model trained on all ad clicks with that of the same model trained only on non-accidental clicks. There, we observe an increase in both ad click-through rate (+3.9%) and revenue (+0.2%) on ads served by the Yahoo Gemini network when using the latter. [...]
Cilia function as calcium-mediated mechanosensors that instruct left-right asymmetry (2023)

The breaking of bilateral symmetry in most vertebrates is critically dependent upon the motile cilia of the embryonic left-right organizer (LRO), which generate a directional fluid flow; however, it remains unclear how this flow is sensed. Here, we demonstrated that immotile LRO cilia are mechanosensors for shear force using a methodological pipeline that combines optical tweezers, light sheet microscopy, and deep learning to permit in vivo analyses in zebrafish. Mechanical manipulation of immotile LRO cilia activated intraciliary calcium transients that required the cation channel Polycystin-2. Furthermore, mechanical force applied to LRO cilia was sufficient to rescue and reverse cardiac situs in zebrafish that lack motile cilia. Thus, LRO cilia are mechanosensitive cellular levers that convert biomechanical forces into calcium signals to instruct left-right asymmetry.
Low-cost On-Chip Structures for Combating Die and IC Recycling (2014)

The recycling of electronic components has become a major concern for the industry and government as it potentially impacts the security and reliability of a wide variety of electronic systems. The sheer number of component types (analog, digital, mixed-signal) and sizes (large or small) makes it extremely challenging to find a one-size-fits-all solution to detect and prevent recycled ICs. In this paper, we propose a suite of solutions for combating die and IC recycling (CDIR). These solutions include light-weight, on-chip structures based on ring oscillators (RO-CDIR), anti-fuses (AF-CDIR) and fuses (F-CDIR). Each structure meets the unique needs and limitations of different part types and sizes providing excellent coverage of recycled parts. HSPICE simulation results using 90nm technology demonstrate the effectiveness of our proposed negative-bias temperature instability (NBTI)-aware RO-CDIR for detecting ICs used for very short period of time. Recycling of large digital ICs can effectively be detected by using AF-CDIR. Small analog and digital recycled components can be identified by testing our F-CDIR with very low cost measurement devices, e.g., a multimeter.
Enrichment of rare variants in population isolates: single AICDA mutation responsible for hyper-IgM syndrome type 2 in Finland (2016)

Antibody class-switch recombination and somatic hypermutation critically depend on the function of activation-induced cytidine deaminase (AID). Rare variants in its gene AICDA have been reported to cause autosomal recessive AID deficiency (autosomal recessive hyper-IgM syndrome type 2 (HIGM2)). Exome sequencing of a multicase Finnish family with an HIGM2 phenotype identified a rare, homozygous, variant (c.416T>C, p.(Met139Thr)) in the AICDA gene, found to be significantly enriched in the Finnish population compared with other populations of European origin (38.56-fold, P<0.001). The population history of Finland, characterized by a restricted number of founders, isolation and several population bottlenecks, has caused enrichment of certain rare disease-causing variants and losses of others, as part of a phenomenon called the Finnish Disease Heritage. Accordingly, rare founder mutations cause the majority of observed Finnish cases in these mostly autosomal recessive disorders that consequently are more frequent in Finland than elsewhere. Screening of all currently known Finnish patients with an HIGM2 phenotype showed them to be homozygous for p.(Met139Thr). All the Finnish p.(Met139Thr) carriers with available data on their geographic descent originated from the eastern and northeastern parts of Finland. They were observed to share more of their genome identity by descent (IBD) than Finns in general (P<0.001), and they all carried a 207.5-kb ancestral haplotype containing the variant. In conclusion, the identified p.(Met139Thr) variant is significantly enriched in Finns and explains all thus far found AID deficiencies in Finland.
ZnO Nanorods with Low Intrinsic Defects and High Optical Performance Grown by Facile Microwave-Assisted Solution Method (2015)

Vertically aligned ZnO nanorods were grown at 90 °C by both microwave synthesis and traditional heated water bath method on Si (100) substrate with a precoated ZnO nanoparticle seed layer. A detailed comparison in the morphology, defects, and optical properties of the ZnO nanorods grown by the two methods across the pH range of 10.07-10.9 for microwave synthesis and conventional heated water bath method was performed using scanning electron microscopy, photoluminescence, and X-ray photoelectron spectroscopy. The results show that the microwave route leads to more uniformly distributed nanorods with a lower density of native defects of oxygen interstitials and zinc vacancies. The microwave synthesis presents a promising new approach of fabricating metal oxide nanostructures and devices toward green applications.
Nonbinary Social Choice: An Impossibility Theorem (1982)

This paper contains a generalization of the General Possibility Theorem to situations where choice over two-element (more generally, “small”) sets is not possible. The analysis is developed in terms of the social choice function formulation rather than the social welfare function approach. In this formulation, assumptions concerning the size of sets of feasible alternatives are explicit, allowing the role of these assumptions in inducing impossibility results to be explored.
Phylogeny of a Novel Family of Human Endogenous Retrovirus Sequences, HERV-W, in Humans and Other Primates (1999)

A novel human endogenous retrovirus, HERV-W, has been characterized on the basis of multiple sclerosis-associated retrovirus (MSRV) probes. We have analyzed the phylogenetic distribution of HERV-W in humans and other primate species. As HERV-W presents a C/D chimeric nature and is largely composed of deleted elements, Southern blots were performed using gag, pol, env, and LTR probes. The relative complexities observed for gag, pol, env, and LTR regions were similar in humans, apes, and Old World monkeys, the minimal number of bands observed after Southern blot analysis being 25, 50, 10, and at least 100, respectively. The HERV-W family entered the genome of catarrhines more than 25 million years ago.
Effect of Huanglongbing or Greening Disease on Orange Juice Quality, a Review (2019)

Huanglongbing (HLB) or citrus greening is the most severe citrus disease, currently devastating the citrus industry worldwide. The presumed causal bacterial agent <i>Candidatus</i> Liberibacter spp. affects tree health as well as fruit development, ripening and quality of citrus fruits and juice. Fruit from infected orange trees can be either symptomatic or asymptomatic. Symptomatic oranges are small, asymmetrical and greener than healthy fruit. Furthermore, symptomatic oranges show higher titratable acidity and lower soluble solids, solids/acids ratio, total sugars, and malic acid levels. Among flavor volatiles, ethyl butanoate, valencene, decanal and other ethyl esters are lower, but many monoterpenes are higher in symptomatic fruit compared to healthy and asymptomatic fruit. The disease also causes an increase in secondary metabolites in the orange peel and pulp, including hydroxycinnamic acids, limonin, nomilin, narirutin, and hesperidin. Resulting from these chemical changes, juice made from symptomatic fruit is described as distinctly bitter, sour, salty/umami, metallic, musty, and lacking in sweetness and fruity/orange flavor. Those effects are reported in both Valencia and Hamlin oranges, two cultivars that are commercially processed for juice in Florida. The changes in the juice are reflective of a decrease in quality of the fresh fruit, although not all fresh fruit varieties have been tested. Earlier research showed that HLB-induced off-flavor was not detectable in juice made with up to 25% symptomatic fruit in healthy juice, by chemical or sensory analysis. However, a blend with a higher proportion of symptomatic juice would present a detectable and recognizable off flavor. In some production regions, such as Florida in the United States, it is increasingly difficult to find fruit not showing HLB symptoms. This review analyzes and discusses the effects of HLB on orange juice quality in order to help the citrus industry manage the quality of orange juice, and guide future research needs.
Drug Discovery: Collaborations between Contract Research Organizations and the Pharmaceutical Industry (2018)

Collaborations between the pharmaceutical industry and contract research organizations continue to represent an attractive alternative to internal drug discovery within a single organization. This Viewpoint covers many of the business models and strategies that are employed in industry-contract research organization collaborations.
Blockage and Coverage Analysis with MmWave Cross Street BSs Near Urban Intersections (2017)

Millimeter wave (mmWave) communication offers Gbps data transmission, which can support massive data sharing in vehicle-to-infrastructure (V2I) networks. In this paper, we analyze the blockage effects among different vehicles and coverage probability of a typical receiver, considering cross street BSs near urban intersections in a multi-lane mmWave vehicular network. First, a three-dimensional model of blockage among vehicles on different lanes is considered. Second, we compute the coverage probability considering the interference of cross street base stations. Incorporating the blockage effects, we derive an exact and semi closed-form expression of the cumulative distribution density (CDF) of the association link path gain. Then, a tight approximation of the coverage probability is computed. We provide numerical results to verify the accuracy of the analytic results. We demonstrate the effects of blockage and the cross street interference. Also, we compare coverage probability with different BSs intensities under various street settings. It is shown that in multi-lane V2I networks, blockage among vehicles is not significant. Also, deploying more BSs does not increase coverage probability efficiently in ultra-dense streets.
Mapping of Redox Energies (1998)

Abstract Electrochemical discharge/charge curves vs Lithium of coin cells using as cathodes various transition-metal oxide hosts for lithium insertion/extraction reactions provide information on the operative redox energies of the transition-metal atoms. The relative positions of the redox energies were found to vary little, but their absolute positions by as much as 1 eV, with changes in structure or, for an isostructural series, with changes in counter cation. Use of polyanions to obtain a more open framework with a larger free volume for Li+-ion motion was found to be more important for high-power applications than the loss in electronic mobility, but a larger free volume for ionic motion reduces the capacity per unit volume. It was shown that introduction of a second phase with a higher redox energy provides a buffer against over discharge. A reversible decrease in capacity with increasing current density was identified and its origin discussed. Substitution of the polyanions (PO4)3− or (SO4)2− for oxide ions brings the V4+/V3+ and Fe3+/Fe2+ redox energies to levels of interest for cathodes in a lithium-ion battery.
100 mm integration of III-V and silicon-on-insulator wafers for the realization of distributed feedback silicon evanescent lasers (2008)

100 mm wafer bonding of InP-based structure and silicon-on-insulator wafers is presented with the use of a lowtemperature (300 °C) O2 plasma-assisted wafer bonding process. An efficient vertical outgassing channels (VOCs) design is developed to eliminate the fundamental obstacle of interfacial voids in bonding due to intrinsic chemical reactions. Generated gas species of H<sub>2</sub>O and H<sub>2</sub> can quickly diffuse to VOCs, etched through-holes to buried oxide layer (BOX), and absorbed by the BOX layer owing to the open network structure and large gas permeability. The interfacial void density is reduced from 55,093 cm<sup>-2</sup> down to 3 cm<sup>-2</sup>, more than five orders of magnitude reduction for appropriate design of VOCs. Uniform patterning of VOCs leads to no outgassing "dead zone" across the entire bonding area, and decrease of the thermal mismatch-induced interfacial strain potentially as well, which both result in the wafer scale-independent bonding. In addition, we present distributed feedback silicon lasers realized on the hybrid silicon evanescent platform. The laser operates continuous wave with a single mode output at 1600 nm. A continuous wave (CW) low threshold of 25 mA with a maximum output power of 5.4 mW is demonstrated at 10 °C. The obtained side mode suppression ratio of 50 dB, 3.6 MHz linewidth, and over 100 nm single mode operation band are comparable to those of commercial III-V DFB devices. These highly single mode lasers may find applications in computer interconnect.
Information geometry and estimation of Toeplitz covariance matrices (2014)

The estimation of covariance matrix is of fundamental importance in radar signal processing. Recent work has shown that information geometry provides a novel approach to estimating the covariance matrix. Prior work has shown that an information geometry inspired covariance matrix estimator provides significant gains (in SINR loss terms) over several standard estimators, such as the loaded sample matrix inversion (LSMI). In this paper, some techniques for computing the covariance matrix, inspired by information geometry, are presented. It is found that some algorithms provide superior performance when the number of samples is small.
Prediction of preferred ClearType filters using the S-CIELAB metric (2008)

The appearance of rendered text is a compromise between the designer's intent and the display capabilities. The ClearType rendering method is designed to enhance rendered text by exploiting the subpixel resolution available on color displays. ClearType represents the high-resolution font outline at the full subpixel resolution of the display and then filters the image to enhance contrast and reduce color artifacts. The filter choice influences text appearance, and people have clear preferences between the renderings with different filters. In this paper, we predict these preferences using S-CIELAB, a spatial extension to the perceptual color metric CIELAB. We calculate the S-CIELAB difference between designed and rendered fonts for various filters. We compare the size of these differences with preference data obtained from individual subjects.
Synthesis and Antiviral Studies of Unsaturated Analogues of Isomeric Dideoxynucleosides (1999)

Novel isomeric dideoxynucleosides with unsaturation in the carbohydrate moiety have been synthesized. For example, isod4A was synthesized through a rearrangement reaction involving a cyclonucleoside. Support for the structures of both purine and pyrimidine d4 compounds came from UV, NMR, HRMS and single crystal X-ray data. Interestingly, the single crystal X-ray data for isod4C shows that the base is almost orthogonal to the carbon-carbon double bond of the sugar moiety. Consistent with this is the observation that the UV data of this compound does not show a bathochromic shift compared to the saturated compound implying that the pi-bond is not in conjugation with the pyrimidine base.
Stimulated resonant inelastic X-ray scattering in a solid (2022)

Abstract When materials are exposed to X-ray pulses with sufficiently high intensity, various nonlinear effects can occur. The most fundamental one consists of stimulated electronic decays after resonant absorption of X-rays. Such stimulated decays enhance the number of emitted photons and the emission direction is confined to that of the stimulating incident photons which clone themselves in the process. Here we report the observation of stimulated resonant elastic (REXS) and inelastic (RIXS) X-ray scattering near the cobalt L 3 edge in solid Co/Pd multilayer samples. We observe an enhancement of order 10 6 of the stimulated over the conventional spontaneous RIXS signal into the small acceptance angle of the RIXS spectrometer. We also find that in solids both stimulated REXS and RIXS spectra contain contributions from inelastic electron scattering processes, even for ultrashort 5 fs pulses. Our results reveal the potential and caveats of the development of stimulated RIXS in condensed matter.
ChemInform Abstract: Photochemistry of Phenyl Azide (1993)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Neural Network Based Models (2015)

In this chapter, the use of neural network based models for characterizing and compensating power amplifier nonlinearities is examined. Different topologies of neural networks models and their training algorithms are presented.
Data from Angiogenic Factor and Cytokine Analysis among Patients Treated with Adjuvant VEGFR TKIs in Resected Renal Cell Carcinoma (2023)

&lt;div&gt;AbstractPurpose:&lt;p&gt;The use of VEGFR TKIs for the adjuvant treatment of renal cell carcinoma (RCC) remains controversial. We investigated the effects of adjuvant VEGFR TKIs on circulating cytokines in the ECOG-ACRIN 2805 (ASSURE) trial.&lt;/p&gt;Experimental Design:&lt;p&gt;Patients with resected high-risk RCC were randomized to sunitinib, sorafenib, or placebo. Plasma from 413 patients was analyzed from post-nephrectomy baseline, 4 weeks, and 6 weeks after treatment initiation. Mixed effects and Cox proportional hazards models were used to test for changes in circulating cytokines and associations between disease-free survival (DFS) and cytokine levels.&lt;/p&gt;Results:&lt;p&gt;VEGF and PlGF increased after 4 weeks on sunitinib or sorafenib (&lt;i&gt;P&lt;/i&gt; &lt; 0.0001 for both) and returned to baseline at 6 weeks on sunitinib (corresponding to the break in the sunitinib schedule) but not sorafenib (which was administered continuously). sFLT-1 decreased after 4 weeks on sunitinib and 6 weeks on sorafenib (&lt;i&gt;P&lt;/i&gt; &lt; 0.0001). sVEGFR-2 decreased after both 4 and 6 weeks of treatment on sunitinib or sorafenib (&lt;i&gt;P&lt;/i&gt; &lt; 0.0001). Patients receiving placebo had no significant changes in cytokine levels. CXCL10 was elevated at 4 and 6 weeks on sunitinib and sorafenib but not on placebo. Higher baseline CXCL10 was associated with worse DFS (HR 1.41 per log increase in CXCL10, Bonferroni-adjusted &lt;i&gt;P&lt;/i&gt; = 0.003). This remained significant after adjustment for T-stage, Fuhrman grade, and ECOG performance status.&lt;/p&gt;Conclusions:&lt;p&gt;Among patients treated with adjuvant VEGFR TKIs for RCC, drug–host interactions mediate changes in circulating cytokines. Elevated baseline CXCL10 was associated with worse DFS. Studies to understand functional consequences of these changes are under way.&lt;/p&gt;&lt;/div&gt;