gebhart/patrepeval huggingface dataset:
Rarity based guided state space search (2001)

Article Rarity based guided state space search Share on Authors: Malay K. Ganai Electrical and Computer Engineering, The University of Texas at Austin Electrical and Computer Engineering, The University of Texas at AustinView Profile , Adnan Aziz Electrical and Computer Engineering, The University of Texas at Austin Electrical and Computer Engineering, The University of Texas at AustinView Profile Authors Info & Claims GLSVLSI '01: Proceedings of the 11th Great Lakes symposium on VLSIMarch 2001 Pages 97–102https://doi.org/10.1145/368122.368878Online:01 March 2001Publication History 10citation178DownloadsMetricsTotal Citations10Total Downloads178Last 12 Months2Last 6 weeks0 Get Citation AlertsNew Citation Alert added!This alert has been successfully added and will be sent to:You will be notified whenever a record that you have chosen has been cited.To manage your alert preferences, click on the button below.Manage my AlertsNew Citation Alert!Please log in to your account Save to BinderSave to BinderCreate a New BinderNameCancelCreateExport CitationPublisher SiteGet Access
Effect of Processing on the Antioxidant Vitamins and Antioxidant Capacity ofVigna sinensisVar. Carilla (2005)

Cowpea (Vigna sinensis L. var. Carilla) flours obtained by fermentation with inoculum Lactobacillus plantarum (PF) or with the natural microorganisms present in the flour (NF) and subsequent heat treatment in an autoclave were prepared to study the effect of fermentation on the antioxidant vitamin content and on the antioxidant capacity. Bacterial counts and pH values, vitamins C and E, carotenoids, glutathione (GSH), superoxide dismutase-like activity (SOD-like activity), peroxyl radical-trapping capacity (PRTC), lipid peroxidation in unilamillar liposomes, and Trolox equivalent antioxidant capacity (TEAC) were evaluated in raw and processed cowpea flours. gamma-Tocopherol and delta-tocopherol were found in raw cowpea, whereas vitamin C and carotenoids were not detected. An increase in the vitamin E activity was observed in PF, whereas vitamin C and carotenoids were not detected in fermented cowpea flours. Fermentation or heat treatment in an autoclave after fermentation produced processed cowpea flours with lower PRTC, glutathione content, and SOD-like activity than those of the raw seeds. However, those processes increased the capacity to inhibit the lipid peroxidation in unilamellar lipoposomes and TEAC. According to the results obtained in this study, the fermentation of cowpeas (naturally or with L. plantarum) and fermentation and subsequent heat treatment in an autoclave are good processes to obtain functional cowpea flours having higher antioxidant capacity than the raw legume.
<title>JPEG 2000 file format provides flexible architecture for color encoding</title> (2000)

In the past, there have been a lot of different image file formats, providing a lot of different capabilities. However, the one thing they pretty much all shared was a very limited mechanism for encoding color. Storing a color image today forces developers to take either a 'lowest-common-denominator' approach by using a single standard colorspace in all applications, or by using the capabilities of ICC color management at the loss of wide interoperability. The JPEG 2000 film format changes all this with a new architecture for encoding the colorspace of an image. While the solution is not perfect, It does greatly increase the number of colorspaces that can be encoded while maintaining a very high level of interoperability between applications. This paper describes the color encoding architecture in the JPEG 2000 file format and shows how this new architecture meets the needs of tomorrows imaging applications.
VOLTTRON™: Using distributed control and sensing to integrate buildings and the grid (2016)

New smart grid technologies are creating a significant potential for smart building systems to provide grid services to power system operators. Communication networks and advanced control systems are a necessary enabler of this new potential. VOLTTRON™ was designed as an open-source distributed control and sensing platform for integrating buildings and the power grid by connecting devices, agents in the platform, agents in the Cloud, and signals from the power grid.
Relationships of Retinal Vessel Diameters with Optic Disc, Macular and Retinal Nerve Fiber Layer Parameters in 6-Year-Old Children (2008)

Children's eyes with a smaller optic disc, thinner macula, and thinner retinal nerve fiber layer have narrower retinal vessels. These anatomic relationships may provide new insights into the vascular etiology of various ocular diseases.
Thin infrared-reflective coatings to enhance the fire performance of polymers (2019)

International audience
Allergy prevention - Current recommendations and new insights. (2008)

History of allergic disease in a first degree relative is currently the only useful indicator for increased risk of developing allergic disease in a child. Prevention strategies should be directed to these high risk individuals. Currently, maternal dietary restriction during pregnancy or lactation and aeroallergen avoidance are not recommended. Breastfeeding is recommended, and where not possible or insufficient, a partially hydrolysed formula should be used in high risk infants. Introduction of solids should be delayed to 4-6 months of age. There is no evidence that delaying solids beyond this age is of benefit. There is currently insufficient evidence to recommend the addition of probiotics for allergy prevention.
ChemInform Abstract: Nanocrystalline Gold and Gold—Palladium as Effective Catalysts for Selective Oxidation (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Iterative Approach to the Discovery of Novel Degarelix Analogues:  Substitutions at Positions 3, 7, and 8. Part II (2005)

Degarelix (FE200486, Ac-d-2Nal(1)-d-4Cpa(2)-d-3Pal(3)-Ser(4)-4Aph(l-Hor)(5)-d-4Aph(Cbm)(6)-Leu(7)-ILys(8)-Pro(9)-d-Ala(10)-NH(2)) is a potent and very long acting antagonist of gonadotropin-releasing hormone (GnRH) after subcutaneous administration in mammals including humans. Analogues of degarelix were synthesized, characterized, and screened for the antagonism of GnRH-induced response in a reporter gene assay in HEK-293 cells expressing the human GnRH receptor. The duration of action was also determined in the castrated male rat assay to measure the extent (efficacy and duration of action) of inhibition of luteinizing hormone (LH) release. Structurally, this series of analogues has novel substitutions at positions 3, 7, and 8 and N(alpha)-methylation at positions 6, 7, and 8 in the structure of degarelix. These substitutions were designed to probe the spatial limitations of the receptor's cavity and to map the steric and ionic boundaries. Some functional groups were introduced that were hypothesized to influence the phamacokinetic properties of the analogues such as bioavailability, solubility, intra- or intermolecular hydrogen bond forming capacity, and ability to bind carrier proteins. Substitutions at positions 3 ([N(beta)-(2-pyridyl-methyl)d-Dap(3)]degarelix, IC(50) = 2.71 nM) (5), 7 ([Pra(7)]degarelix, IC(50) = 2.11 nM) (16), and 8 ([N(delta)-(IGly)Orn(8)]degarelix, IC(50) = 1.38 nM) (20) and N-methylation ([N(alpha)-methyl-Leu(7)]degarelix, IC(50) = 1.47 nM) (32) yielded analogues that were equipotent to degarelix (2) in vitro (IC(50) = 1.64 nM) but shorter acting in vivo. Out of the 33 novel analogues tested for the duration of action in this series, two analogues ([N(epsilon)-cyclohexyl-Lys(8)]degarelix, IC(50) = 1.50 nM) (23) and ([N(beta)-(IbetaAla)Dap(8)]degarelix, IC(50) = 1.98 nM) (26) had antagonist potencies and duration of action similar to that of azaline B {inhibited LH (>80%) release for >72 h after sc injection to castrated male rats at a standard dose of 50 mug/rat in 5% mannitol}. Under similar conditions analogues ([N(gamma)-(IGly)Dab(8)]degarelix, IC(50) = 1.56 nM) (21) and ([IOrn(8)]degarelix, IC(50) = 1.72 nM) (18) had a longer duration of action {inhibited LH (>96 h) release} than azaline B; however they were shorter acting than degarelix. Hydrophilicity of these analogues, a potential measure of their ability to be formulated for sustained release, was determined using RP-HPLC at neutral pH yielding analogues with shorter as well as longer retention times. No correlation was found between retention times and antagonist potency or duration of action.
Indoor photovoltaics, The Next Big Trend in solution‐processed solar cells (2021)

Abstract Indoor photovoltaics (IPVs) have attracted considerable interest for their potential to power small and portable electronics and photonic devices. The recent advancemes in circuit design and device optimizations has led to the power required to operate electronics for the internet of things (IoT), such as distributed sensors, remote actuators, and communication devices, being remarkably reduced. Therefore, various types of sensors and a large number of nodes can be wireless or even batteryless powered by IPVs. In this review, we provide a comprehensive overview of the recent developments in IPVs. We primarily focus on third‐generation solution‐processed solar cell technologies, which include organic solar cells, dye‐sensitized solar cells, perovskite solar cells, and newly developed colloidal quantum dot indoor solar cells. Besides, the device design principles are also discussed in relation to the unique characteristics of indoor lighting conditions. Challenges and prospects for the development of IPV are also summarized, which, hopefully, can lead to a better understanding of future IPV design as well as performance enhancement.
Ruolo del virus di Epstein-Barr nella patogenesi dei disordini linfoproliferativi post-trapianto (2003)

I disordini linfoproliferativi post-trapianto (PTLD) rappresentano un gruppo eterogeneo di linfoproliferazioni patologiche, prevalentemente a carico di linfociti B, che insorgono nel contesto di una immunodepressione iatrogena in pazienti che hanno subito un trapianto d'organo o di cellule staminali emopoietiche. A differenza di quanto si verifica per i linfomi non-Hodgkin dei pazienti immunocompetenti, la maggioranza dei PTLD associata all'infezione da parte del virus di Epstein-Barr (EBV), come dimostrato dalla presenza del virus nelle cellule di tali linfoproliferazioni. Quadri clinico-patologici simili ai PTLD si riscontrano anche in associazione con altre condizioni di immunodeficienza, sia di tipo congenito che acquisito (infezione da HIV), e sono anch'essi prevalentemente Tutte queste linfoproliferazioni sono la conseguenza di alterazioni delle risposte immuni che normalmente tengono sotto controllo l'infezione da EBV e che impediscono al virus di estrinsecare il suo potenziale trasformante nei confronti del linfocita B. Tuttavia, alla complessa patogenesi dei PTLD concorrono anche altri fattori, ancora poco noti, sia legati alla cellula EBV-infettata che all'ospite portatore del trapianto. Nella presente rassegna verranno riassunte le recenti acquisizioni sulla biologia dell'infezione da EBV, con particolare riferimento al ruolo di tale virus nella patogenesi dei PTLD. Data la loro rilevanza in termini di gestione clinica del paziente trapiantato, verranno inoltre discussi gli aspetti metodologici e le problematiche applicative inerenti il monitoraggio del carico di EBV nel sangue periferico di questi pazienti. Il virus L'EBV un -herpesvirus umano ubiquitario che infetta pi del 95% della popolazione mondiale (68). La maggior parte delle infezioni primarie si verificano nella prima infanzia e sono generalmente asintomatiche. Tuttavia, quando l'infezione primaria si verifica pi tardivamente, come nei paesi ad elevati standard socio-economici, l'EBV pu causare la mononucleosi infettiva, un disordine linfoproliferativo autolimitante caratterizzato dalla presenza nel torrente circolatorio di un ele-
Moiré contouring: mathematical analysis (1975)

Get PDF Email Share Share with Facebook Tweet This Post on reddit Share with LinkedIn Add to CiteULike Add to Mendeley Add to BibSonomy Get Citation Copy Citation Text Alan L. Browne and Steve M. Rohde, "Moiré contouring: mathematical analysis," Appl. Opt. 14, 1260-1261 (1975) Export Citation BibTex Endnote (RIS) HTML Plain Text Citation alert Save article
EVOLUTION OF IMPLANTABLE, MAGNETICALLY LEVITATED HEARTQUEST??? VAD FOR DESTINATION THERAPY (2004)

AIM: Develop the magnetically levitated HeartQuest™ VAD to support late-stage CHF patients for 10+ years. METHODS: Lessons learned from clinical VAD experience and knowledge of clinical needs for Destination Therapy were applied to configure the HeartQuest VAD. A clinically viable system utilized advances in key components (centrifugal pump, magnetic levitation, brushless motor, and control schemes) that were innovatively integrated. The system's design optimization process relied on a unique computer-based tool that integrated analytical equations and heuristic knowledge for each key component and its behavior under static and dynamic loads. Biocompatibility and hemo-dynamic capacity were evaluated in 22 in vivo studies in calves (2 years cumulative implant time, longest duration 5 months). Anatomic fit and placement were evaluated intra-operatively in twenty consenting adults. RESULTS: The compact HeartQuest LVAD is 75mm in diameter, 35mm thick, and has 22 ml priming volume. The efficacy of completely suspending and rotating the impeller with only a single actively-powered axis of levitation control has been demonstrated. Performance highlights include: - Insignificant hemolysis (110 mg/dl PFH), thrombosis, and minimal pump-related complications in calves - Wide range of operation: from low (0-1.7 L/m) to high (15 Urn) flow rates in calves -Excellent anatomic fit in 1.0–2.9 m2, BSA patients Such results provide the basis to complete and verify the system design for initial clinical trials in the near future.
Evidence that Cd101 Is an Autoimmune Diabetes Gene in Nonobese Diabetic Mice (2011)

We have previously proposed that sequence variation of the CD101 gene between NOD and C57BL/6 mice accounts for the protection from type 1 diabetes (T1D) provided by the insulin-dependent diabetes susceptibility region 10 (Idd10), a <1 Mb region on mouse chromosome 3. In this study, we provide further support for the hypothesis that Cd101 is Idd10 using haplotype and expression analyses of novel Idd10 congenic strains coupled to the development of a CD101 knockout mouse. Susceptibility to T1D was correlated with genotype-dependent CD101 expression on multiple cell subsets, including Foxp3(+) regulatory CD4(+) T cells, CD11c(+) dendritic cells, and Gr1(+) myeloid cells. The correlation of CD101 expression on immune cells from four independent Idd10 haplotypes with the development of T1D supports the identity of Cd101 as Idd10. Because CD101 has been associated with regulatory T and Ag presentation cell functions, our results provide a further link between immune regulation and susceptibility to T1D.
Medial bicompartmental arthroplasty patients display more normal gait and improved satisfaction, compared to matched total knee arthroplasty patients (2021)

III.
A Novel Intramolecular Acylation of unsym-Diacylaminoazetidinone Disulfides. The 3,8-Dioxo-5-thia-2,7-Diazabicyclo[4.2.0]octanes (1986)

h i g h y i e l d s .On t r e a t m e n t w i t h a base such as t r i e t h y l a m i n e , these compounds 1,
BOLD MRI vs. NIR spectrophotometry. Will the best technique come forward? (1998)

This paper will discuss the assumptions, strengths and weaknesses of both BOLD imaging and NIR spectrophotometry with respect to monitoring tissue oxygenation. BOLD, or blood oxygen level dependent MRI, is an imaging protocol that is sensitive to specific relaxation rates which are influenced by deoxyhemoglobin. NIRS is capable of providing information on oxyhemoglobin, deoxyhemoglobin and total hemoglobin. Both techniques have inherent assumptions, strengths and weaknesses. NIRS has not been able to provide the spatial sensitivity of BOLD. BOLD may be more difficult to quantify. Currently, these two methods are complementary, providing data that strengthens the interpretation of results from each modality. Recent data indicate that relaxation rates can be used to quantify deoxyhemoglobin in isolated blood and, under specific conditions, there is a strong correlation between deoxyhemoglobin content measured by NIRS and changes in relaxation rates measured by MRI. These data indicate that BOLD imaging has the potential to become an attractive alternative to NIRS.
Water as an Intrinsic Structural Element in Cellulose Fibril Aggregates (2022)

While strong water association with cellulose in plant cell walls and man-made materials is well-established, its molecular scale aspects are not fully understood. The thermodynamic consequences of having water molecules located at the microfibril-microfibril interfaces in cellulose fibril aggregates are therefore analyzed by molecular dynamics simulations. We find that a thin layer of water molecules at those interfaces can be in a state of thermal equilibrium with water surrounding the fibril aggregates because such an arrangement lowers the free energy of the total system. The main reason is enthalpic: water at the microfibril-microfibril interfaces enables the cellulose surface hydroxyls to experience a more favorable electrostatic environment. This enthalpic gain overcomes the entropic penalty from strong immobilization of water molecules. Hence, those particular water molecules stabilize the cellulose fibril aggregates, akin to the role of water in some proteins. Structural and functional hypotheses related to this finding are presented.
Statistical Characterization of Temperature and Pressure Vertical Profiles for the Analysis of Laser Heterodyne Radiometry Data (2021)

The statistical analysis of historic pressure and temperature profiles from radiosonde launches for use in the fitting of molecular oxygen line shapes is presented. As the O<sub>2</sub> mixing ratio is nearly constant throughout the lower atmosphere, only variations in pressure and temperature profiles will affect the fit of observed O<sub>2</sub> features in Laser Heterodyne Radiometry (LHR) spectra. Radiosonde temperature and pressure data are extracted from the Integrated Global Radiosonde Archive (IGRA) for a given station, date, and launch time. Data may be extracted for a single launch, for the same date over several years, and/or within a window centered on a target date. The temperature and pressure profiles are further characterized by the statistical variation in coefficients of polynomial fits in altitude. The properties of the probability distributions for each coefficient are used to constrain fits of O<sub>2</sub> line shapes through Nelder-Mead optimization. The refined temperature and pressure profiles are then used in the retrieval of vertically resolved mixing ratios for greenhouse gases (GHGs) measured in the same instrument. In continuous collections, each vertical profile determination may be treated as a Bayesian prior to inform subsequent measurements and provide an estimate of uncertainties.
ChemInform Abstract: 25 Years After HIV Discovery: Prospects for Cure and Vaccine (Nobel Lecture) (2009)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Two Prodrugs of Potent and Selective GluR5 Kainate Receptor Antagonists Actives in Three Animal Models of Pain (2005)

Amino acids 5 and 7, two potent and selective competitive GluR5 KA receptor antagonists, exhibited high GluR5 receptor affinity over other glutamate receptors. Their ester prodrugs 6 and 8 were orally active in three models of pain: reversal of formalin-induced paw licking, carrageenan-induced thermal hyperalgesia, and capsaicin-induced mechanical hyperalgesia.
Detomidine Binding to Guinea Pig Liver Imidazoline Receptors (I‐Receptors) Shows Marked Positive Cooperativity (1993)

The binding of [ 3 H]‐idazoxan to guinea pig liver membranes was measured in the presence of 3 μM rauwolscine, which prevented the binding [ 3 H]‐idazoxan to α 2 ‐adrenergic receptors. Under these conditions the radioligand bound to saturable imidazoline receptors (I‐receptors) with a K d of 18 nM and a B max of 665 fmol mg ‐1 protein. Six drugs which were used to compete for [ 3 H]‐idazoxan in the liver caused competition curves of widely varying steepness. Fitting the competition curves to the standard four parameter logistic function showed that the Hill coefficients (n H ) varied from 2.02 (detomidine) to 0.43 (UK‐14,304), The n H 's obtained in liver for the six compounds correlated strongly (r = 0.99; P&lt; 0.001) with the corresponding n H 's obtained in a previous study on the guinea pig kidney where the drugs were also tested in competition with [ 3 H]‐idazoxan (Wikberg et al. 1992). Good correlation was also found for the Log(K i ) values of drugs determined in the two tissues (r = 0.96; P&lt; 0.005). Whereas the standard logistic function accurately described the competition curves of the 5 drugs tested in the liver for which the competition curve Hill coefficients varied between 0.43 to 1.41 (UK‐14,304, rilmenidine, histamine and d‐ and 1‐medetomidine), it did not accurately fit the detomidine competition curves. Instead the detomidine competition curves could be more accurately described by a model composed of the sum of two independent logistic functions. Using this model detomidine appeared to compete with [ 3 H]‐idazoxan with two apparent affinity components, one with a K i of 0.26 μM and an n H of 3.24 and the other with a K i of 4.9 μM and an n H of 1.09. The proportion of the affinity components were 72% of the higher and 28% of the lower affinity. The data are discussed with the notion that guinea pig liver and kidney I‐receptors are similarly regulated by both positive and negative allosteric cooperative interactions.
Analysis of Nonrepeatable Radial Vibration of Magnetic Disk Spindles (1991)

The nonrepeatable radial vibration (NRRV) of spindle motors used in magnetic disk memory devices was studied in detail. In particular a theoretical and experimental investigation on the comparison of NRRV in time and frequency domains was conducted. The random and statistical characteristics of NRRV were ascertained by analyzing the amplitude distributions of both asynchronous and synchronous vibration components in the frequency domain. It was found that the main part of NRRV is composed of asynchronous components in most of the spindles tested. Some of the asynchronous component amplitudes, varying randomly, can be approximated by Rayleigh distribution function. It was also found that the synchronous vibrations include nonrepeatable components. The variance of NRRV measured in the time domain was shown theoretically and experimentally to be equal to the sum of the total power of asynchronous components and the total variance of synchronous components. From this relation, the cause of tracking error in such memory devices can be analyzed quantitatively in frequency domain.
Ambulatory atrioventricular synchronous pacing over time using a leadless ventricular pacemaker: Primary results from the AccelAV study (2022)

Accelerometer-based mechanical atrial sensing provided by a leadless pacemaker implanted in the right ventricle significantly improves quality of life in a select cohort of patients with AV block and normal sinus function. AVS remained stable through 3 months, and there were no system upgrades to dual-chamber pacemakers.