gebhart/patrepeval huggingface dataset:
Heterogeneous Sensor Correlation: A Case Study of Live Traffic Analysis (2001)

As enterprises deploy multiple intrusion detection sensors at key points in their networks, the issue of correlating messages from these sensors becomes increasingly important. A correlation capability reduces alert volume, and potentially improves detection performance through sensor reinforcement or complementarity. Correlation is especially advantageous when heterogeneous sensors are employed because of the potential to aggregate different views of the same incident. Emerging standards for sensor interoperability with respect to alert reporting facilitate the function of correlation engines, but these standards are still at an early stage of development. Furthermore, it is apparent that these standards will not enforce uniformity in, for example, attack description, complicating the task of correlation. The immature state of standards and nonuniformity of reporting both argue for correlation technologies that are robust, flexible, and function with comparatively few underlying assumptions. Herein, we present a case study of correlating several sensors listening to live traffic using a probabilistic correlation approach. Keywords: Network security, sensor correlation, alert management, adaptive systems Acknowledgment. This research is sponsored by DARPA under contract numbers F30602-99-C-0149 and N66001-00-C-8058. The views herein are those of the author(s) and do not necessarily reflect the views of the supporting agency. * This work was performed while Dan Andersson was an International Fellow at the System Development Laboratory, SRI International. Correspondence should be sent to Mr. Valdes. - 2 -
Clinical role of pathological downgrading after radical prostatectomy in patients with biopsy confirmed G leason score 3 + 4 prostate cancer (2014)

While patients with pathological Gleason score 3 + 3 with tertiary Gleason pattern ≤4 at RP in patients with biopsy Gleason score 3 + 4 prostate cancer may be potential candidates for AS, decision curve analysis showed limited utility of our model to identify such men. Future study is needed to identify new predictors to help identify potential candidates for AS among patients with biopsy confirmed Gleason score 3 + 4 prostate cancer.
Investigation of the Mechanical Behavior of Microbeam-Based MEMS Devices (2001)

An investigation into the responses of microbeams to electric actuations is presented. Attention is focused mainly on the use of microbeams in two important MEMS-based devices: capacitive microswitches and resonant microsensors. Nonlinear models are developed to simulate the behavior of the microbeams in each device. The models account for mid-plane stretching, an applied axial load, a DC electrostatic force, and, for the case of resonant sensors, an AC harmonic force. Further, a novel method that uses a reduced-order model is introduced for simulating the behavior of microbeams under a DC electrostatic force. The presented method shows attractive features, like for example, a high stability near the pull-in and a low computational cost. Thus, it can be of significant benefit to the development of MEMS design software. The static behavior of microbeams under electrostatic forces is studied using two methods. One method employs a shooting technique for solving the boundary-value problem that governs the static behavior. The second method is based on solving an algebraic system of equations obtained from the reduced-order model. Further, the eigenvalue problem describing the vibrations of a microbeam around its statically deflected position is solved using a shooting method to obtain the microbeam mode shapes and natural frequencies. The dynamic behavior of resonant microbeams is also investigated. A perturbation method, the method of multiple scales, is used to obtain two first-order nonlinear ordinary-differential equations that describe the amplitude and phase of the response and its stability. The results show that an inaccurate representation of the system nonlinearities may lead to an erroneous prediction of the nonlinear resonance frequency of a microbeam. The case of three-to-one internal resonance between the lowest two modes is treated. Finally, the reduced-order model is used to study the dynamic behavior of the electrostatically actuated microbeams. The proposed models are validated by comparing their results with experimental results available in the literature.
ChemInform Abstract: Novel Structural Analogues of Glyphosate Based on Azoles. Part 1. Synthesis of 1H‐Imidazoles Containing Carboxyl and Phosphoryl Groups in the Ring. (2011)

Abstract A general method for the synthesis of 1H‐imidazoles containing a phosphoryl and a carboxyl group is developed and applied to the preparation of glyphosate mimetic (VII).
Measurement of vortex shedding in the wake of a sphere at (2019)

Flow in the wake of a sphere has been studied for at least the last hundred years. The three-dimensional (3-D) flow structure has been observed many times using dye visualization and prior to the direct numerical simulations by Johnson &amp; Patel ( J. Fluid Mech. , vol. 378, 1999, pp. 19–70), its structure at a Reynolds number of approximately 300, was believed to consist of a one-sided chain of hairpin-like vortices. However, the numerical simulations by Johnson &amp; Patel ( J. Fluid Mech. , vol. 378, 1999, pp. 19–70) also showed that so-called ‘induced’ vortices were generated. The present results are the first spatially resolved measurements that elucidate the 3-D vortex shedding cycle in the wake of a sphere at a Reynolds number of 465. Tomographic particle image velocimetry (tomo-PIV) enabled snapshots of the vortical structure and by combining these results with temporally resolved planar PIV, the ensemble averaged shedding cycle in the wake of the sphere was reconstructed. The present results clearly indicate that besides the ‘primary’ vortex chain shed from the sphere, secondary (‘induced’) vortices are generated by transforming transverse vorticity into streamwise vorticity as a result of the interaction between the sphere’s separating shear layer and the counter-rotating longitudinal vortices extending downstream from the sphere.
Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis (2023)

Compensatory endocytosis keeps the membrane surface area of secretory cells constant following exocytosis. At chemical synapses, clathrin-independent ultrafast endocytosis maintains such homeostasis. This endocytic pathway is temporally and spatially coupled to exocytosis; it initiates within 50 ms at the region immediately next to the active zone where vesicles fuse. However, the coupling mechanism is unknown. Here, we demonstrate that filamentous actin is organized as a ring, surrounding the active zone at mouse hippocampal synapses. Assuming the membrane area conservation is due to this actin ring, our theoretical model suggests that flattening of fused vesicles exerts lateral compression in the plasma membrane, resulting in rapid formation of endocytic pits at the border between the active zone and the surrounding actin-enriched region. Consistent with model predictions, our data show that ultrafast endocytosis requires sufficient compression by exocytosis of multiple vesicles and does not initiate when actin organization is disrupted, either pharmacologically or by ablation of the actin-binding protein Epsin1. Our work suggests that membrane mechanics underlie the rapid coupling of exocytosis to endocytosis at synapses.
Tuning the Fermi Level of SiO2-Supported Single-Layer Graphene by Thermal Annealing (2010)

The effects of thermal annealing in inert Ar gas atmosphere of SiO2-supported, exfoliated single-layer graphene are investigated in this work. A systematic, reproducible change in the electronic properties of graphene is observed after annealing. The most prominent Raman features in graphene, the G and 2D peaks, change in accord to what is expected in the case of hole doping. The results of electrical characterization performed on annealed, back-gated field-effect graphene devices show that the neutrality point voltage VNP increases monotonically with the annealing temperature, confirming the occurrence of excess hole accumulation. No degradation of the structural properties of graphene is observed after annealing at temperatures as high as 400 °C. Thermal annealing of single-layer graphene in controlled Ar atmosphere can therefore be considered a technique to reproducibly modify the electronic structure of graphene by tuning its Fermi level.
Charging and Accounting (2006)

This chapter contains sections titled: Architecture Call Detail Records Transfer Account Procedure Files Inter-operator Accounting of CAMEL Calls Correlation of Call Detail Records Global Call Reference Call Party Handling CDRs
Impact of lymphadenectomy on the treatment of endometrial cancer using data from the JSOG cancer registry (2020)

Despite the limitations of a retrospective study with some biases, the results suggest that LN dissection in endometrial cancer has a prognostic effect.
Selective Synthesis of (2Z,4E)‐Dienyl Esters by Ene—Diene Cross Metathesis. (2007)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Convergence of the adhesive and fibrinolytic systems: recognition of urokinase by integrin αMβ2 as well as by the urokinase receptor regulates cell adhesion and migration (2003)

Previous studies demonstrated that integrin alpha(M)beta(2) (CD11b/18, Mac-1) forms a physical complex with the urokinase-type plasminogen activator receptor (uPAR/CD87) on leukocytes. In this study, we used human peripheral blood neutrophils and transfected cells expressing alpha(M)beta(2), uPAR, or both receptors to show that the integrin can directly interact with urokinase (uPA). We demonstrate that alpha(M)beta(2) supported adhesion and migration of these cells to uPA, and, in each case, blockade of alpha(M)beta(2) suppressed the response. Within uPA, both the kringle and proteolytic domains are recognized by alpha(M)beta(2), which are distinct from the growth factor domain that binds to uPAR. Within the alpha(M) subunit of the integrin, the I domain interacts with uPA, which is distinct from the region that interacts with uPAR. On cells expressing uPAR and alpha(M)beta(2), both receptors mediated adhesion and migration. This cooperation was particularly apparent in the responses of neutrophils to uPA, where blockade of alpha(M)beta(2) reduced uPAR-mediated responses and engagement of uPAR enhanced recognition of uPA by alpha(M)beta(2). Thus, recognition of uPA by alpha(M)beta(2) allows for formation of a multicontact trimolecular complex, in which a single uPA ligand may bind simultaneously to both uPAR and alpha(M)beta(2). This complex may play an important role in the control of inflammatory cell migration and vascular homeostasis.
Intranode data communications in a parallel computer (2023)

Intranode data communications in a parallel computer that includes compute nodes configured to execute processes, where the data communications include: allocating, upon initialization of a first process of a computer node, a region of shared memory; establishing, by the first process, a predefined number of message buffers, each message buffer associated with a process to be initialized on the compute node; sending, to a second process on the same compute node, a data communications message without determining whether the second process has been initialized, including storing the data communications message in the message buffer of the second process; and upon initialization of the second process: retrieving, by the second process, a pointer to the second process's message buffer; and retrieving, by the second process from the second process's message buffer in dependence upon the pointer, the data communications message sent by the first process.
A Kinetic Study of Catalytic Activity Degradation of La0.6Sr0.4Co0.2Fe0.8O3-δ (2009)

The long term performance of La 0.6 Sr 0.4 Co 0.2 Fe 0.8 O 3-δ (LSCF) was evaluated using electrical conductivity relaxation (ECR). The degradation rate of the chemical exchange coefficient (kchem) was faster than that of the chemical diffusion coefficient (Dchem) when LSCF was aged at 800 oC, which indicates surface degradation during the test. No crystallographic phase changes were detected by X-ray diffraction (XRD). Scanning electron microscopy (SEM), however, showed a significant change in surface morphology. SEM energy dispersive spectroscopy (EDS) and Auger electron spectroscopy (AES) showed that the surface was separated into two regions: A Sr rich phase on the grain boundaries and a Sr deficient top surface layer surrounding it. Transition metals were deficient in both phases. It is proposed that Sr is initially enriched to the top surface and diffuses to the grain boundary by surface diffusion. The preferential growth of Sr rich particles might be related to the Cr poisoning from the thermocouple sheath. From defect chemistry it is shown that both Sr rich particles and Sr deficient surface can contribute to the degradation of the catalytic activity of the cathode material by the reducing the oxygen vacancy and transition metal concentration.
Impact of detector geometry for compressive fan beam snapshot coherent scatter imaging (2016)

Previous realizations of coded-aperture X-ray diffraction tomography (XRDT) techniques based on pencil beams image one line through an object via a single measurement but require raster scanning the object in multiple dimensions. Fan beam approaches are able to image the spatial extent of the object while retaining the ability to do material identification. Building on these approaches we present our system concept and geometry of combining a fan beam with energy sensitive/photon counting detectors and a coded aperture to capture both spatial and spectral information about an object at each voxel. Using our system we image slices via snapshot measurements for four different detector configurations and compare their results.
A Novel Design of E-Textile Integration for Physiological Monitoring and Lighting (2018)

This research was to focus on integrating printed textile circuit board, FPCB (flexible printed circuit board), and IC Chips into a fabric for physiological monitoring. This cloth can be used to detect physiological signals such as heart rate, ECG, movement, temperature, and respiration. The main disadvantage of traditional smart textiles remains in the bulk volume of the attached rigid hardware equipment, which makes the user uncomfortable. To overcome this problem, the main idea is to minimize the hardware size, make it compatible with the textile structure and integrate the electronics into textiles directly. The prototype was tested in indoor/outdoor environment. All the physiological data were transmitted into a remote database server and an online monitoring system was used to supervise the physical state of wearer. The main advantage of this design is the new type of conductive junction which is smaller and softer. The size of conductive junction can be tremendously reduced down to 0.5mm*0.5mm compared with the current buckle junction. This novel design of the printed electronics embedded textile technology leads the e-textile physiological monitoring system to a higher tendency of the washable, flexible, stretchable and thin characteristic of the pure textile.
Thermo-optic tuning of silicon nitride microring resonators with low loss non-volatile $$\hbox {Sb}_{2}\hbox {S}_{3}$$ phase change material (2022)

A new family of phase change material based on antimony has recently been explored for applications in near-IR tunable photonics due to its wide bandgap, manifested as broadband transparency from visible to NIR wavelengths. Here, we characterize [Formula: see text] optically and demonstrate the integration of this phase change material in a silicon nitride platform using a microring resonator that can be thermally tuned using the amorphous and crystalline states of the phase change material, achieving extinction ratios of up to 18 dB in the C-band. We extract the thermo-optic coefficient of the amorphous and crystalline states of the [Formula: see text] to be 3.4 x [Formula: see text] and 0.1 x 10[Formula: see text], respectively. Additionally, we detail the first observation of bi-directional shifting for permanent trimming of a non-volatile switch using continuous wave (CW) laser exposure ([Formula: see text] to 5.1 dBm) with a modulation in effective refractive index ranging from +5.23 x [Formula: see text] to [Formula: see text] x 10[Formula: see text]. This work experimentally verifies optical phase modifications and permanent trimming of [Formula: see text], enabling potential applications such as optically controlled memories and weights for neuromorphic architecture and high density switch matrix using a multi-layer PECVD based photonic integrated circuit.
Borrelia burgdorferiEscape Mutants That Survive in the Presence of Antiserum to the OspA Vaccine Are Killed When Complement Is Also Present (1998)

ABSTRACT As an initial attempt to investigate the possible role of outer surface protein A (OspA) escape mutants of Borrelia burgdorferi in decreasing the efficacy of the OspA vaccine, mutants of the HB19 strain of B. burgdorferi sensu stricto were selected in vitro from an uncloned, low-passage-number isolate. The antiserum used for selection was obtained from rhesus monkeys that had been given a vaccine of the same formulation and dose, and by the same route of administration, as that given to humans in several trials. All of the mutants selected in liquid medium and subsequently cloned twice in solid medium expressed a single abundant protein of 28 to 34 kDa instead of both OspA and OspB. Depending on the mutant, this protein reacted strongly, weakly, or not detectably with the anti-OspA antibody used for selection. Analysis of the ospAB locus of each of four representatives from these three groups of mutants by PCR with oligonucleotide primers that hybridize to flanking regions of the ospAB operon, and of the corresponding phenotype with monoclonal antibodies that bind to the amino or carboxyl terminus of the OspA or OspB polypeptide, indicated that in all cases a deletion within the operon had occurred. Spirochetes from the four mutant strains chosen for further analysis could be killed in antibody-dependent, complement-mediated killing assays with the selecting anti-OspA antibody, despite their resistance to killing with this antibody in the absence of complement. Complement-mediated killing occurred at an antibody concentration higher than that required to kill wild-type spirochetes. If anti-OspA antibody acts only within the tick, where complement is probably ineffective due to tick-derived decomplementing factors, then OspA escape mutants, if infectious, could seriously diminish the efficacy of OspA vaccines. On the other hand, if the killing of B. burgdorferi with anti-OspA antibody also takes place within the human host, then our results indicate that chimeric/deletion escape mutants will be killed as well.
NeoFox: annotating neoantigen candidates with neoantigen features (2021)

Supplementary data are available at Bioinformatics online.
Supplemental Figure S3 from Akt Inhibition Enhances Expansion of Potent Tumor-Specific Lymphocytes with Memory Cell Characteristics (2023)

&lt;p&gt;Supplemental Figure S3. Surface phenotype of Akti-treated and vehicle TIL isolated from patient with melanoma and expanded to clinical scale for 30 days prior to adoptive-transfer into humanized mouse model.&lt;/p&gt;
[Laparoscopic cholecystectomy versus classical cholecystectomy]. (1996)

The authors evaluated the results after classical (CCHE) and laparoscopic cholecystectomies (LCHE) in the period from March 16 1994 to June 30 1995. In this period they operated on 408 patients, out of which 208 were operated by the laparoscopic technique. There were no differences in postoperative morbidity. The mortality after laparoscopic surgery was 0% and the classical cholecystectomy reached the morbidity of 1.4%. Complicated patients were usually operated in the classical way. The time of hospitalisation after LCHE was 5.2 days and after CCHE 8.3 days. The results of LCHE were as follows: morbidity 10.5%, conversions 2.4%, reoperations 1.4%, and no leakage of the bile duct. We saved 40% of costs using LCHE. All these facts show that LCHE is advantageous, secure and well tolerated by patients. The patients prefer comfort after the operation, good cosmetic effect and a short hospital isation. CCHE did not lose its position, especially in complicated cases. (Tab. 5, Ref. 21.)
Learning Chaotic Attractors by Neural Networks (2000)

An algorithm is introduced that trains a neural network to identify chaotic dynamics from a single measured time series. During training, the algorithm learns to short-term predict the time series. At the same time a criterion, developed by Diks, van Zwet, Takens, and de Goede (1996) is monitored that tests the hypothesis that the reconstructed attractors of model-generated and measured data are the same. Training is stopped when the prediction error is low and the model passes this test. Two other features of the algorithm are (1) the way the state of the system, consisting of delays from the time series, has its dimension reduced by weighted principal component analysis data reduction, and (2) the user-adjustable prediction horizon obtained by "error propagation"-partially propagating prediction errors to the next time step. The algorithm is first applied to data from an experimental-driven chaotic pendulum, of which two of the three state variables are known. This is a comprehensive example that shows how well the Diks test can distinguish between slightly different attractors. Second, the algorithm is applied to the same problem, but now one of the two known state variables is ignored. Finally, we present a model for the laser data from the Santa Fe time-series competition (set A). It is the first model for these data that is not only useful for short-term predictions but also generates time series with similar chaotic characteristics as the measured data.
Hexachlorophene as a topically applied chemical for prophylaxis against Schistosoma mansoni infections in mice (1985)

Treatment of mouse tail skins with hexachlorophene (1.25% w/v) in absolute methanol or 70% isopropanol suppressed Schistosoma mansoni infections by more than 95% even when the application was performed up to three days prior to exposure to cercarial suspensions by tail immersion. Treatment with concentrations of 0.313% or higher one day prior to exposure provided at least 98% protection when the treated surface was not subjected to water washes of greater duration than 1/2 hour. Tail immersion application of 1.25% hexachlorophene one day prior to exposure still provided 87-92% protection after 3 hours water wash. Wipe application of 1.25% hexachlorophene three days prior to exposure still provided 93% protection following 3 hours water wash. High cercarial recoveries from exposure tubes at the end of exposure periods indicated high antipenetrant activity for hexachlorophene. Sufficient hexachlorophene leached from treated tail skins into the surrounding water to affect subsequently added cercariae so that they were no longer infective to untreated mice.