gebhart/patrepeval huggingface dataset:
Additions and Corrections - Rational Synthesis of Unidimensional Mixed Valence Solids. Structural, Spectral, and Electrical Studies of Charge Distribution and Transport in Partially Oxidized Nickel and Palladium Bisdephenylglyoximates (1979)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAdditions and Corrections - Rational Synthesis of Unidimensional Mixed Valence Solids. Structural, Spectral, and Electrical Studies of Charge Distribution and Transport in Partially Oxidized Nickel and Palladium BisdephenylglyoximatesMartin Cowie, Alain Gleizes, Gregory Grynkewich, Davida Kalina, Malcolm McClure, Raymond Scaringe, Robert Teitelbaum, Stanley Ruby, James Ibers, Carl Kannewurf, and Tobin MarksCite this: J. Am. Chem. Soc. 1979, 101, 24, 7438Publication Date (Print):November 1, 1979Publication History Published online19 February 2004Published inissue 1 November 1979https://pubs.acs.org/doi/10.1021/ja00518a608https://doi.org/10.1021/ja00518a608research-articleACS PublicationsRequest reuse permissionsArticle Views17Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Achievable Sum DoF of the K-User MIMO Interference Channel with Delayed CSIT (2016)

This paper considers a $K$-user multiple-input-multiple-output (MIMO) interference channel (IC) where 1) the channel state information obtained by the transmitters (CSIT) is completely outdated, and 2) the number of transmit antennas at each transmitter, i.e., $M$, is greater than the number of receive antennas at each user, i.e., $N$. The usefulness of the delayed CSIT was firstly identified in a $K$-phase Retrospective Interference Alignment (RIA) scheme proposed by Maddah-Ali et al for the Multiple-Input-Single-Output Broadcast Channel, but the extension to the MIMO IC is a non-trivial step as each transmitter only has the message intended for the corresponding user. Recently, Abdoli et al focused on a Single-Input-Single-Output IC and solved such bottleneck by inventing a $K$-phase RIA with distributed overheard interference retransmission. In this paper, we propose two $K$-phase RIA schemes suitable for the MIMO IC by generalizing and integrating some key features of both Abdoli's and Maddah-Ali's works. The two schemes jointly yield the best known sum Degrees-of-Freedom (DoF) performance so far. For the case $\frac{M}{N}{\geq}K$, the achieved sum DoF is asymptotically given by $\frac{64}{15}N$ when $K{\to}\infty$.
Editorial: Advancing the treatment landscape in Parkinson's disease using sensor technology and data-driven modeling (2022)

EDITORIAL article Front. Aging Neurosci., 20 December 2022Sec. Parkinson’s Disease and Aging-related Movement Disorders Volume 14 - 2022 | https://doi.org/10.3389/fnagi.2022.1113818
Environmental aging of epoxy based stereolithography partsPart 1 – Moisture transport (2012)

Current epoxy based stereolithography materials are highly hygroscopic. However, the diffusion of moisture into these materials and the effect this has on the mechanical performance of manufactured parts have not been thoroughly investigated to date. The first part of this paper will discuss the transport of moisture into representative stereolithography materials and the second part of the paper will describe the effect of the absorbed moisture on mechanical performance. Moisture transport in three different epoxy based stereolithography materials has been investigated using mass uptake experiments. The results show that anomalous (non-Fickian) diffusion occurs to varying degrees in all three materials, the characteristic uptake appearing to be pseudo-Fickian. Anomalous uptake models based on dual sorption, diffusion–relaxation and a dual Fickian model were all shown to provide an excellent fit to the data. The effects of relative humidity and sample thickness are also investigated in the paper.
Survey on Dermatophytes Isolated from Animals in Switzerland in the Context of the Prevention of Zoonotic Dermatophytosis (2023)

Most inflammatory dermatophytoses in humans are caused by zoophilic and geophilic dermatophytes. Knowledge of the epidemiology of these fungi in animals facilitates the prevention of dermatophytosis of animal origin in humans. We studied the prevalence of dermatophyte species in domestic animals in Switzerland and examined the effectiveness of direct mycological examination (DME) for their detection compared to mycological cultures. In total, 3515 hair and skin samples, collected between 2008 and 2022 by practicing veterinarians, were subjected to direct fluorescence microscopy and fungal culture. Overall, 611 dermatophytes were isolated, of which 547 (89.5%) were from DME-positive samples. Cats and dogs were the main reservoirs of <i>Trichophyton mentagrophytes</i> and <i>Microsporum canis</i>, whereas <i>Trichophyton benhamiae</i> was predominantly found in guinea pigs. Cultures with <i>M. canis</i> significantly (<i>p</i> < 0.001) outnumbered those with <i>T. mentagrophytes</i> in DME-negative samples (19.3% versus 6.8%), possibly because <i>M. canis</i> can be asymptomatic in cats and dogs, unlike <i>T. mentagrophytes</i>, which is always infectious. Our data confirm DME as a reliable, quick, and easy method to identify the presence of dermatophytes in animals. A positive DME in an animal hair or skin sample should alert people in contact with the animal to the risk of contracting dermatophytosis.
Dynamic Analysis of MEMS Resonators Under Primary-Resonance Excitation (2005)

We present a dynamic analysis and simulation of electrically actuated microelectromechanical systems (MEMS) resonators under primary-resonance excitation. We use a shooting technique, perturbation techniques, and long-time integration of the equation of motion to investigate the global dynamics of the resonators. We study the dynamic pull-in instability and show various scenarios and mechanisms for its occurrence. Our results show that dynamic pull-in can occur through a saddle-node bifurcation, a period-doubling bifurcation, or homoclinic tangling, depending on factors such as the initial conditions of the device and the level of the electrostatic force.
The Most Frequent Aminoglycoside Resistance Mechanisms--Changes with Time and Geographic Area: A Reflection of Aminoglycoside Usage Patterns? (1997)

The aminoglycoside resistance mechanisms revealed by two surveys in Europe and other countries have been compared to those revealed in earlier studies. Mechanisms have become more complex in all bacterial groups. In Providencia, Serratia, Pseudomonas, Acinetobacter, and Staphylococcus species isolates, genus-specific mechanisms were very common, and it was not possible to see differences between different geographic areas. In other Enterobacteriaceae, the increasing complexity of mechanisms was most often caused by combinations of gentamicin-modifying enzymes with AAC(6')-I, which acetylates amikacin but not gentamicin. The occurrence of these combinations varied by geographical region and among hospitals. The frequency of these combinations correlated with aminoglycoside usage in either the geographical regions or in individual hospitals. These broad-spectrum combinations occurred most frequently in Citrobacter, Enterobacter, and Klebsiella species but also occurred in Escherichia, Morganella, Proteus, Salmonella, and Shigella species. Often the only clinically available aminoglycoside that retained its normal activity was isepamicin.
Regulation of Growth Hormone and Prolactin Gene Expression and Secretion by Chimeric Somatostatin-Dopamine Molecules (2007)

Dopamine (DA) regulates both prolactin (PRL) secretion and gene expression, whereas somatostatin (SRIF) inhibits GH secretion with unclear effects on GH gene expression. We therefore tested the effects of SRIF analogs and chimeric SRIF/DA compounds BIM 23A760 and BIM 23A761 on GH and PRL secretion and gene expression in primary rat pituitary cultures and pituitary tumor GH(3) and MMQ cells. Chimeric SRIF/DA molecules suppressed GH release with a similar efficacy to SRIF receptor subtype 2 agonists in rat pituitary and GH(3) cells. After 24 h, BIM 23A760 and BIM 23A761 did not exert additive effects on GH secretion, and after 48 h were less effective than the combination of respective mono-receptor agonists in GH(3) cells. Real-time PCR did not reveal changes in GH mRNA levels after treatment with SRIF analogs and SRIF/DA molecules. SRIF/DA compounds suppressed PRL and PRL mRNA in rat pituitary and MMQ cells with a similar efficacy to D(2)-DA receptor agonist. In GH(3) cells, they suppressed PRL and PRL mRNA levels with a similar efficacy to SRIF receptor subtype 2 agonists. SRIF/DA molecules did not exhibit additive effects on PRL secretion and mRNA levels as compared with cotreatment with mono-receptor ligands. The results show that SRIF analogs and SRIF/DA molecules inhibit GH and PRL secretion and suppress PRL but not GH gene expression.
Inflammation in AKI (2015)

Inflammation is a complex biologic response that is essential for eliminating microbial pathogens and repairing tissue after injury. AKI associates with intrarenal and systemic inflammation; thus, improved understanding of the cellular and molecular mechanisms underlying the inflammatory response has high potential for identifying effective therapies to prevent or ameliorate AKI. In the past decade, much knowledge has been generated about the fundamental mechanisms of inflammation. Experimental work in small animal models has revealed many details of the inflammatory response that occurs within the kidney after typical causes of AKI, including insights into the molecular signals released by dying cells, the role of pattern recognition receptors, the diverse subtypes of resident and recruited immune cells, and the phased transition from destructive to reparative inflammation. Although this expansion of the basic knowledge base has increased the number of mechanistically relevant targets of intervention, progress in developing therapies that improve AKI outcomes by modulation of inflammation remains slow. In this article, we summarize the most important recent developments in understanding the inflammatory mechanisms of AKI, highlight key limitations of the commonly used animal models and clinical trial designs that may prevent successful clinical application, and suggest priority approaches for research toward clinical translation in this area.
The interval of linkage disequilibrium (LD) detected with microsatellite and SNP markers in chromosomes of Finnish populations with different histories (2003)

Linkage disequilibrium (LD) has been an efficient tool for fine mapping of monogenic disease genes in population isolates. Its usefulness for identification of predisposing loci for common, polygenic diseases has been challenged on the basis of anticipated allelic and locus heterogeneity. We compared the extent of LD among marker loci in Finnish subpopulations with divergent but well-characterized histories. One study sample represents the early settlement Finnish population, descended from two immigration events 4,000 and 2,000 years ago. The second sample represents the geographically large late settlement region, populated 15 generations ago by several small immigrant groups from the early settlement region. The third is a restricted regional subpopulation in northeastern Finland which was founded 12 generations ago by 39 immigrant families from the late settlement region. We genotyped 243 microsatellite markers and 68 single nucleotide polymorphisms (SNPs) on chromosomes 1q and 5q. The genealogy of the families from the early (n=16) and late settlements (n=54) and the isolated settlement (n=54) was studied in detail back to the 1800s. Microsatellite data revealed greater LD in the young, founder subpopulation than was seen in either of the older populations. Observed linkage disequilibrium correlated not only with physical distance between markers but also with the information content of the markers. Using biallelic SNP markers, significant LD could only be detected up to 0.1 cM. Our results demonstrate the complexity of the concept of 'detectable LD' and emphasize the importance of understanding population history when designing a strategy for disease gene mapping.
A Schlieren system for optical visualization of ultrasonic fields. (2009)

Ultrasonic field mapping is an essential component of transducer characterization and of beam forming verification. Such measurements are commonly performed by displacing a hydrophone over a range of points within the field; these procedures can be time-consuming. A calibrated hydrophone can provide accurate measurements of the field, subject to limitations of bandwidth and aperture of the device. A rapid qualitative 2D measurement of the spatial acoustic field can be obtained by optical means, in which the change in optical index due to the presence of acoustic pressure is imaged using a schlieren approach. This technique illuminates a transparent refracting acoustic medium using a plane collimated source and then focuses the transmitted light using a lens or mirror. In the absence of acoustic field, all of the light focuses to a small spot; acoustically induced refractive index perturbations cause some of the light to focus elsewhere. Obscuring the primary focal spot of unperturbed light with a mask permits imaging only the perturbations in the acoustic medium. We will describe a mirror-based schlieren system for imaging continuous as well as pulsed fields and with color corresponding qualitatively to the intensity of the field. [Work supported by NIH CA109556 and EB007643.]
Crystal-field effects on the far-infrared cation vibrations of transition metal (2+) ion exchanged faujasite zeolites (1985)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCrystal-field effects on the far-infrared cation vibrations of transition metal (2+) ion exchanged faujasite zeolitesGeoffrey A. Ozin, Mark D. Baker, John Godber, and Shihua WuCite this: J. Am. Chem. Soc. 1985, 107, 7, 1995–2000Publication Date (Print):April 1, 1985Publication History Published online1 May 2002Published inissue 1 April 1985https://pubs.acs.org/doi/10.1021/ja00293a033https://doi.org/10.1021/ja00293a033research-articleACS PublicationsRequest reuse permissionsArticle Views157Altmetric-Citations27LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Fire retardancy of a new polypropylene-grafted starch: Part II: investigation of mechanisms (2013)

Mechanisms of fire retardancy of intumescent Gaialene® (a polypropylene-grafted starch, containing ammonium polyphosphate as flame retardant) exhibiting high performance (60% reduction of the peak of heat release rate at 35 kW/m 2 , high limiting oxygen index (30 vol% O 2 ), and UL-94 V0 ranking at 1.6 mm and V2 at 0.8 mm) have been investigated by thermogravimetric analysis coupled with Fourier transform infrared gas phase analysis, by pyrolysis/gas chromatography/mass spectroscopy, by rheology, and by solid-state nuclear magnetic resonance. It was shown that phosphoric acid released upon fire acts in solid phase by catalyzing the degradation of starch, enhancing the development of an intumescent shield protecting the polymer.
<title>Modal noise simulations due to high-frequency VCSEL numerical aperture fluctuations</title> (1998)

We have experimentally identified and characterized two dynamic components of a VCSEL/multimode optical fiber link: (1) a high temporal frequency fluctuation of the VCSEL's numerical aperture (NA) and, (2) source power spectrum shift in time (chirp) both upon ac modulation. We use these variables of the excitation irradiance distribution at a fiber input to simulate the resulting modal noise; without the typical assumptions that all fiber modes are equally filled and all relative fiber mode delays are equally probable. Results indicate that fluctuations in the NA can generate significant modal noise at the fiber output. On the other hand, source chip, in the presence of mode selective loss, is only moderately effective in generating modal noise. Moreover, since chirping increases with the VCSEL's series resistance, it's significance will diminish as design efforts to decrease the potential drop across the VCSEL are successful.
Shifting factor—A new paradigm for studying the rheology of cementitious suspensions (2020)

Abstract One of the main challenges when studying the rheology of cementitious systems is that cement particles are large and susceptible to gravity, in particular in dispersed systems. This implies that the range of volume fractions over which rheological properties of cement pastes can be measured is limited, as too high water content causes segregation and too low water content results in pastes that are too cohesive to measure. Consequently, the impact of the volume fraction of solids on yield stress is still not reliably established. A similar situation is encountered when studying cementitious systems with superplasticizers, whose impact is highly dependent on dosage. An important issue here is that admixture effects cannot be reliably established with respect to nonadmixed references as the latter ones can most often not be measured at the volume fractions for which admixed pastes do not segregate. The “Shifting factor” approach presented in this paper overcomes this long‐standing issue establishing exponential dependences of yield stress both with respect to volume fraction and admixture adsorption.
T-Cell Defect in Diffuse Large B-Cell Lymphomas Involves Expansion of Myeloid Derived Suppressor Cells Expressing IL-10, PD-L1, and S100A12 (2015)

Abstract Introduction: In diffuse large B-cell lymphoma (DLBCL), the number of circulating monocytes and neutrophils represents an independent prognostic factor. These cells include monocytic and granulocytic myeloid derived suppressor cells (M- and G-MDSCs) defined by their ability to suppress T-cell responses. MDSCs are a heterogeneous population described in inflammatory or infectious diseases as well as in numerous tumors including multiple myeloma, chronic lymphocytic leukemia and DLBCL. However, their mechanisms of action in DLBCL remain unclear. The aim of the study was to investigate the presence and mechanisms of suppression of MDSC subsets in DLBCL. Methods: Whole blood from 56 DLBCL at diagnosis and 45 healthy donors (HD) were analyzed by flow cytometry. Quantitative Real Time PCR were analyzed on Taqman@ array microfluidic cards. Cytokine levels in plasma and culture supernatants were measured by Luminex and Elisa. T-cell proliferation after monocyte depletion or treatment with inhibitors, was analyzed by CFSE assay. Results: By flow cytometry, we identified an expansion of G-MDSC (Linneg HLA-DRneg CD33pos CD11bpos) and M-MDSC (CD14pos HLA-DRlow) in DLBCL compared to HD (p&lt;0.001). Interestingly, only M-MDSC number was correlated with the International Prognostic Index (IPI), the event-free survival (EFS), and the number of circulating Treg. Furthermore, T-cell proliferation was restored after monocyte depletion. To identify the mechanism of suppression involved, we evaluated the gene expression of key enzymes (ARG1, IDO1, NOS2, HO-1 and PTGS2) or immunomodulatory molecules (IL10, TGF β1, CD274/PD-L1, S100A8, S100A9, S100A12) involved in MDSC biology. ARG1, IDO1, IL10, CD274/PD-L1 and S100A12 were significantly up-regulated in DLBCL (p&lt;0.05). At the protein level arginase 1, IL-10 and S100A12 were increased in DLBCL plasma, whereas PD-L1 expression on monocyte was increased in DLBCL compared to HD (p=0.03). Arginase 1 and IDO activities where increased in DLBCL patients. In DLBCL, IL-10 and S100A12 were detected in culture supernatants from stimulated PBMC and these molecules were decreased after CD14pos depletion (p&lt;0.05). Finally, we defined 2 groups of DLBCL depending on M-MDSC content and analyzed the percentage of proliferating T cells after CD3/CD28 stimulation in the presence of various inhibitors or blocking antibodies (L-1MT, nor-NOHA, anti-IL-10, anti-PD-1 and anti-S100A12). In the group of patients with circulating MDSC, neutralizing IL-10, PDL-1 and S100A12 resulted in an increase of CD4 and/or CD8 T-cell proliferation. Conclusion: In summary, we identified MDSC subsets expanded in DLBCL as well as new mechanisms of immunosuppression in DLBCL. Myeloid-dependent T-cell suppression is attributed to a release of IL-10 and S100A12 and an increase of PD-L1 expression. Disclosures Cartron: Roche: Consultancy, Honoraria; GSK: Honoraria; Celgene: Honoraria; Sanofi: Honoraria; Gilead: Honoraria.
A single-electron analysis of NAND flash memory programming (2015)

We present the first single-electron analysis of the program operation of NAND Flash arrays. The analysis leads, first of all, to a direct extraction not only of the average value but also of the statistical spread of the control-gate to floating-gate cell capacitance (Cpp). This allows, then, to assess the impact of Cpp variability, electron injection statistics and read noise on the distribution of the threshold-voltage shift coming from a programming pulse applied to the array cells. Finally, the electron leakage through the inter-gate dielectric along program is easily and directly quantified under real operating conditions.
Simulating the impact of poly-CD wafer-level and die-level variation on circuit performance (2002)

In this paper, we present a methodology for simulating the impact of wafer-level (within-wafer) and die-level (within-die) variation on circuit performance. For a sample 0.25 /spl mu/m 64/spl times/8 SRAM layout, the impact of both die-level and wafer-level poly-CD variation as measured through signal skew and delay is shown to be significant.