gebhart/patrepeval huggingface dataset:
Metal atom to cluster to bulk transformations. Electron spin resonance studies of silver atoms in rare gas matrices at 12 K. Quantum size effect (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTMetal atom to cluster to bulk transformations. Electron spin resonance studies of silver atoms in rare gas matrices at 12 K. Quantum size effectGeoffrey A. OzinCite this: J. Am. Chem. Soc. 1980, 102, 9, 3301–3303Publication Date (Print):April 1, 1980Publication History Published online1 May 2002Published inissue 1 April 1980https://pubs.acs.org/doi/10.1021/ja00529a093https://doi.org/10.1021/ja00529a093research-articleACS PublicationsRequest reuse permissionsArticle Views112Altmetric-Citations28LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Integrating occlusion culling with view-dependent rendering (2001)

We present a novel approach that integrates occlusion culling within the view-dependent rendering framework. View-dependent rendering provides the ability to change level of detail over the surface seamlessly and smoothly in real-time. The exclusive use of view-parameters to perform level-of-detail selection causes even occluded regions to be rendered in high level of detail. To overcome this serious drawback we have integrated occlusion culling into the level selection mechanism. Because computing exact visibility is expensive and it is currently not possible to perform this computation in real time, we use a visibility estimation technique instead. Our approach reduces dramatically the resolution at occluded regions.
A Sol‐Gel‐Based Approach to Synthesize High‐Surface‐Area Pt—Ru Catalysts as Anodes for DMFCs. (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
Delayed-Action Interaction and Spin-Orbit Coupling between Solitons (2001)

We report on new fundamental phenomena in soliton interactions: delayed-action interaction and "spin"-orbit coupling upon collision between two-dimensional composite solitons carrying topological charges.
An achievable region for the double unicast problem based on a minimum cut analysis (2011)

We consider the multiple unicast problem under network coding over directed acyclic networks when there are two source-terminal pairs, $s_1-t_1$ and $s_2-t_2$. Current characterizations of the multiple unicast capacity region in this setting have a large number of inequalities, which makes them hard to explicitly evaluate. In this work we consider a slightly different problem. We assume that we only know certain minimum cut values for the network, e.g., mincut$(S_i, T_j)$, where $S_i \subseteq \{s_1, s_2\}$ and $T_j \subseteq \{t_1, t_2\}$ for different subsets $S_i$ and $T_j$. Based on these values, we propose an achievable rate region for this problem based on linear codes. Towards this end, we begin by defining a base region where both sources are multicast to both the terminals. Following this we enlarge the region by appropriately encoding the information at the source nodes, such that terminal $t_i$ is only guaranteed to decode information from the intended source $s_i$, while decoding a linear function of the other source. The rate region takes different forms depending upon the relationship of the different cut values in the network.
OP15 Efficacy of ustekinumab for Ulcerative Colitis through 4 years: Final clinical and endoscopy outcomes from the UNIFI long-term extension (2023)

Abstract Background Ustekinumab (UST) is an interleukin12/23p40 antagonist approved for treatment of moderate to severe Ulcerative Colitis (UC). Here we report final clinical outcomes based on the Mayo score, including the endoscopy subscore, from the UNIFI long-term extension (LTE) study through 4 years of UST treatment. Methods Overall, 523 intravenous UST induction responders were randomised to subcutaneous maintenance therapy: 175 placebo (PBO); 172 UST 90 mg every 12 weeks (q12w); 176 UST 90 mg q8w. A total of 284 UST patients (pts) completed week (wk)44 and continued treatment in the LTE; pts receiving PBO were discontinued after study unblinding. Starting at wk56, randomised pts with UC worsening could receive a dose adjustment: PBO to UST q8w, UST q12w to UST q8w, and UST q8w to UST q8w (sham adjustment). Outcomes based on the Mayo score (including endoscopy assessed by a local reader) were evaluated at the final efficacy visit (wk200); pts who had treatment failure (i.e., had ostomy or colectomy or discontinued UST due to lack of therapeutic effect or worsening UC) before wk200 were also included, and they were imputed as nonresponders. Clinical remission was defined as a Mayo score ≤2 points and no individual subscore &amp;gt;1; clinical response as a decrease in Mayo score of ≥30% and ≥3 points from induction baseline with either a decrease in rectal bleeding subscore of ≥1 from induction baseline or a rectal bleeding subscore of 0 or 1; modified Mayo score (without Physician’s Global Assessment subscore) response as a decrease in modified Mayo score of ≥30% and ≥2 points from induction baseline with either a decrease in rectal bleeding subscore of ≥1 from induction baseline or a rectal bleeding subscore of 0 or 1; and endoscopic improvement as an endoscopy subscore of 0 or 1. Results Among 205 pts who were randomised to UST at maintenance baseline and continued treatment in the LTE, who either had Mayo score data (including endoscopy) at wk200 or had experienced treatment failure, 58.0% were in clinical remission, 80.0% were in clinical response, 79.5% were in modified Mayo score response, and 67.3% showed endoscopic improvement (Figure 1). Using an alternative “as observed case” analysis (without imputation for treatment failures), among 171 randomised pts who continued UST treatment through LTE and had an endoscopy score at wk200, 69.6% were in clinical remission, 95.9% were in clinical response, 95.3% were in modified Mayo score response, and 80.7% showed endoscopic improvement. Conclusion Among these pts with a history of moderate to severe UC who continued UST treatment, approximately 2/3 or more were in clinical remission, clinical response, and/or demonstrated endoscopic improvement at 4 years.
Crystal chemistry of brannockite, KLi3Sn2 Si12O30, from a new occurrence in the Golden Horn Batholith, Washington State, USA (2015)

A second locality of the milarite-group mineral brannockite (ideally KLi 3 Sn 2 Si 12 O 30 ) has been discovered at Liberty Bell/Washington Pass in the alkaline granite of the Golden Horn Batholith, Okanogan County, Washington, USA as sub-millimeter euhedral bladed clear crystals in a single miarolitic cavity in a biotite granite. The Washington Pass brannockite shows micro-scale compositional zoning involving tetravalent A-site Sn 4+ , Zr 4+ , Ti 4+ , and Hf 4+ substitution and the coupled substitution A (X 4+ )+ B □ ⇔ A (Fe/Al) 3++B (Na, K) + . In contrast, brannockite analyzed from the type locality in the late hydrothermal zone of the Li-Sn-rich pegmatite of the Foote Mine, Kings Mountain, North Carolina, USA exhibits near end-member composition with only minor Na + , Al 3+ , and Ti 4+ . Single-crystal X-ray diffraction of Washington Pass brannockite confirms the space group P 6/ mcc with unit-cell parameters a = 10.014(2)A, c = 14.268(5)A, and V = 1239.16(8)A 3 . Washington Pass brannockite co-exists with its Zr-analogues, both the milarite-group sogdianite and the related tuhualite-group mineral zektzerite. Selected samples of both minerals show Sn as minor element. The sogdianite contains unusually low Na and Ti compared to most other localities and has near endmember composition. The results emphasize the high compatibility of the milarite structure with different heterovalent cations, associated with the cation-size dependent coupled distortion of the octahedral A and tetrahedral T2 sites.
Stimulation of Stress-activated Protein Kinase and p38 HOG1 Kinase in Murine Keratinocytes following Photodynamic Therapy with Benzoporphyrin Derivative (1996)

The activation state of the members of the mitogen-activated protein kinase family following photodynamic therapy (PDT) with benzoporphyrin derivative monoacid ring A was investigated using a naturally transformed murine keratinocyte cell line, Pam 212. PDT involves the use of photosensitizer molecules and a specific wavelength of visible light. The process of PDT generates singlet oxygen and other reactive oxygen intermediates (ROIs), and the cytotoxic effect of these ROIs is the basis for the use of PDT to treat cancer and psoriasis. PDT caused a strong dose- and time-dependent activation of both stress-activated protein kinase (SAPK) and p38 HOG1. The maximum activation of SAPK and p38 HOG1 occurred between 20 and 30 min following PDT treatment with 200 ng/ml benzoporphyrin derivative monoacid ring A and 2 J/cm2 of red light at 690 nm. In our system, PDT did not cause significant activation of extracellularly regulated kinase (ERK) 1 and ERK2. Under the same experimental conditions, ultraviolet light irradiation caused strong activation of SAPK and p38 HOG1 and minimum activation of ERK1 and ERK2 in Pam212 cells. A number of ROI scavengers were tested for their effect on PDT-induced SAPK and p38 HOG1 activation. Both L-histidine and N-acetyl-L-cysteine showed a significant inhibitory effect on PDT-induced SAPK and p38 HOG1 activation. This indicated that PDT-induced SAPK and p38 HOG1 activation may be partially mediated by ROI.
IMMUNOMODULATION AND TOLERANCE WITH IL-2/FC IN COMPOSITE TISSUE ALLOTRANSPLANTATION (2010)

Jindal, R.; Unadkat, J. V.; Zhang, D.; Ng, T. W.; Pulikkottil, B. J.; Wang, Y.; Zanoun, R.; Sucher, R.; Weinstock, M.; Gorantla, V. S.; Lee, W. P.A.; Zheng, X. X. Author Information
Resistive memories: Which applications? (2014)

Recent announcement of 16Gbits Resistive memory from Sony shows the trend to quickly adopt resistive memories as an alternative to DRAM. However, using ReRAM for embedded computing is still a futuristic goal. This paper approaches two applications based on ReRAM-devices for gaining area, performance or power consumption. The first application is FPGA, one of the first architecture that can benefit the most from ReRAM integration to reduce footprint and save energy. The second application relates to ultra-low-power systems and the way to obtain an instantaneous “freeze” mode in devices for Internet of Things.
Resistance Mechanisms to AZD9291 and Rociletinib—Response (2017)

We would like to take the opportunity and respond to the letter of Dr. Nele Van der Steen and her colleagues that discusses our recent publication in which we describe heterogenic patterns or resistance to third-generation EGFR inhibitors. It is correct that we primarily focused on the description
Deep-learning-based motion artefact measures for coronary CT angiography images (2019)

Poster: ECR 2019 / C-0850 / Deep-learning-based motion artefact measures for coronary CT angiography images by: Lossau1, M. Vembar2, H. Nickisch1, T. Wissel1, R.-D. Bippus1, M. Morlock1, M. Grass 1; 1Hamburg/DE, 2Cleveland/US
Absolute linear-in-k spectrometer designs enabled by freeform optics (2019)

Linear-in-wavenumber, k, spectrometers have the merits of saving signal processing time and improving the sensitivity of spectral-domain optical coherence tomography (SD-OCT) by avoiding post-k-interpolation. We report on an approach leveraging freeform optics to linearize spectrometers in k to achieve an extremely low residual k-nonlinearity in design. A freeform lens reduced the k-nonlinearity from 2.47% for a benchmark spectrometer to 2.79 × 10<sup>-5</sup>% and 3.36 × 10<sup>-9</sup>% using the Fringe Zernike coefficients up to the 16<sup>th</sup> term and 37<sup>th</sup> term, respectively. A simulation model was developed to evaluate the performance of SD-OCT with the designed spectrometers. Without the k-interpolation in software, results show that the two freeform spectrometers achieve a roll-off gain of 5.24 dB over the imaging depth from 0.5 to 5.5 mm, while the maximum imaging depth is 5.8 mm. Finally, a 4.2-µm-FWHM axial PSF was maintained throughout the imaging depth in air.
Candida albicans reprioritizes metal handling during fluconazole stress (2019)

Maintenance of metal homeostasis is critical to cell survival due to the multitude of cellular processes that depend on one or more metal cofactors. Here, we show that the opportunistic fungal pathogen Candida albicans extensively remodels its metal homeostasis networks to respond to treatment with the antifungal drug fluconazole. Disruption of the ergosterol biosynthetic pathway by fluconazole requires C. albicans adaptation, including increased Cu import and storage, increased retention of Fe, Mn, and Zn, altered utilization of Cu- and Mn-dependent enzymes, mobilization of Fe stores, and increased production of the heme prosthetic group utilized by the enzyme target of fluconazole. The findings offer a new perspective for thinking about fungal response to drug stress that pushes cells out of their metal homeostatic zones, leading them to enact metal-associated adaptation mechanisms to restore homeostasis to survive.
Electronmicroscopic Observations of the Effect of Electron Irradiation and Print-Out Effect on AgBr Crystal (1966)

The effects of the electron irradiation on the two kinds of silver bromide micro crystals which were prepared from the photographic process plate and the SSS photographic film were studied. The print-out effect on the specimens from the SSS film were observed directly and by using replica with an electronmicroscope. It was found that whiskers grew from the side face of the grain with intense electron irradiation, while the (111) surface showed no appreciable change. In the crystals from the SSS photographic film, the triangular pattern consisting of three protrusions appeared on the well-developed (111) surface, while the square pattern appeared on the (100) face with electron irradiation or exposure to the sun light. It was also found that the tripyramidal pits appeared on the (111) face with much longer electron irradiation or exposure to he sun light.
A negative feedback regulatory loop between miR-138 and TP53 is mediated by USP10 (2019)

TP53 is a critical tumor suppressor. In approximately 50% of human cancers the TP53 gene is either lost or mutated. The expression level of TP53 in the cells is tightly controlled by a fine-tune machinery, mainly through the Mdm2-mediated ubiquitination pathway. On the other side, the ubiquitinated TP53 could be reversed and stabilized by USP7 and USP10, to keep the amount of TP53 in check. MicroRNAs can negatively regulate TP53 expression levels through direct targeting or positively regulate TP53 function through the repression of negative regulators of TP53. Here we report that microRNA-138 controls TP53 expression by directly targeting USP10. Furthermore, TP53 represses microRNA-138 expression, forming a negative feedback regulatory loop. This finding adds another layer of complexity to the TP53 network.
Military IoT: Tactical Edge Clouds for Content Sharing Across Heterogeneous Networks (2022)

Just as inexpensive and powerful devices are driving ecosystems of connected Internet of Things in work and home environments, the battlefield has experienced a proliferation of and reliance on networked devices. However, current networking technologies are ill-suited for content sharing in these emerging military networks where fixed infrastructures and constant connectivity cannot be assumed. The communication paradigm, content-based networking, is proving to be a highly effective solution for operation in mobile infrastructure-less environments where intermittent and disrupted connectivity is expected. We present approaches and tradeoffs for content-centric military IoT architectures that facilitate generation and dissemination of content in challenging tactical edge environments. These architectures are designed to address information flow across different underlying tactical data links by managing the dissemination of mission-critical information across an overlay network optimized for disconnected, intermittent, and limited (DIL) connectivity operations.
Whispering gallery mode in periodic InGaN‐based hexagonal nanoring arrays grown by rf‐MBE using Ti‐mask selective‐area growth (2009)

Abstract We fabricated periodic InGaN‐based hexagonal nanoring arrays by rf‐molecular beam epitaxy (rf‐MBE) with Ti‐mask selective‐area growth (SAG). Multiple photoluminescence peaks from InGaN‐based hexagonal nanorings were observed in room temperature photoluminescence (RT‐PL) measurements with a 325 nm He–Cd laser. We employed a simple plane wave model and a two‐dimensional finite difference time domain (2D‐FDTD) method in the numerical analysis to investigate these multiple peaks. Experimental data was in good coincidence with calculated data, evincing that whispering gallery modes (WGMs) supported in the InGaN‐based hexagonal nanorings were responsible for the multipeaks.
Development of acquired resistance to lapatinib may sensitise HER2-positive breast cancer cells to apoptosis induction by obatoclax and TRAIL (2018)

Our findings highlight the possibility of targeting altered apoptotic signalling to overcome acquired lapatinib resistance, and identify potential novel treatment strategies, with potential biomarkers, for HER2-positive breast cancer that is resistant to HER2 targeted therapies.
Primary Atypical Pneumonia Due toMycoplasma pneumoniae(Eaton Agent) (1963)

RECENT evidence from seroepidemiologic and volunteer studies has established Eaton agent (Mycoplasma pneumoniae∥) as the causative agent of cold agglutinin-positive primary atypical pneumonia.2 3 4 5 In the majority of untreated cases the duration of the illness is generally two or three weeks, with complete resolution of the clinical and radiographic abnormalities.6 This report describes an unusually severe case in which the patient was in the hospital for six weeks and in which a residual radiographic abnormality was present one year after the onset of illness. Diagnosis was established by isolation of M. pneumoniae and the development of a sixteenfold rise . . .
Periovulatory Changes in the Expression of Inhibin α-, βA-, and βB-Subunits in Hormonally Induced Immature Female Rats (1989)

Immature female rats were treated with PMSG and human CG to induce ovulation. Sequential treatment with these hormones allowed us to investigate variations in the production of inhibin subunits shortly before ovulation and during the induced luteal phase. Using this model, we found that expression patterns for the alpha-, beta A-, and beta B-subunits were similar to those observed in mature cycling animals: administration of PMSG (to mimic the gonadotropin surge) led to a sharp increase in the expression of all three subunits in large preovulatory follicles whereas injection with human CG (to induce ovulation) caused a decrease in the levels of the respective mRNAs. In contrast to mature females, shortly before ovulation, levels of inhibin alpha-subunit mRNA were low in small antral follicles (approximately 350 microns). In addition, at that time, inhibin beta A- and beta B-subunits mRNAs were present in several large follicles (greater than 500 microns). More than 2 days after ovulation, inhibin beta A- and beta B-subunit mRNAs could not be detected in small antral size follicles (approximately 350 microns) of hormonally induced females. On the other hand, hybridization signals for the inhibin alpha-subunit were observed in some small antral and preantral size follicles, while signals were very low or undetectable in a large number of atretic follicles. Using this synchronized ovulation model, hybridization patterns for inhibin beta A-subunit mRNA was observed in interstitial cells, 8-10 h after ovulation.(ABSTRACT TRUNCATED AT 250 WORDS)
Long-term follow-up of Asian patients younger than 46 years with acute myeloid leukemia in first complete remission: comparison of allogeneic vs. autologous hematopoietic stem cell transplantation (2006)

Optimal therapy for patients with acute myeloid leukemia (AML) in first complete remission (CR-1) remains the subject of debate: with the possibilities of chemotherapy alone, autologous (auto) or allogeneic (allo) hematopoietic stem cell transplantation (HSCT). We undertook a retrospective analysis of AML patients aged below 46 years and in CR-1, who had undergone auto- or allo-HSCT in our institution, to determine the factors associated with a better outcome. Between September 1985 and April 2003, 81 patients underwent autologous (n = 29) or allogeneic (n = 52) HSCT in CR-1. With a median follow-up of 10 years, the probability of 15-year overall survival (OS) was 51%[95% confidence interval (CI) = 32 - 70%] for auto-HSCT vs. 55% (95% CI = 42 - 69) for allo-HSCT, respectively (P = 0.92). The cumulative incidence of relapse at 3 years was 49% (95% CI = 30 - 67) (auto) vs. 21% (95% CI = 10 - 30) (allo), respectively. Non-relapse-related mortality at 3 years was 5% (95% CI = 0 - 14) (auto) vs. 17% (95% CI = 7 - 28) (allo), respectively. This retrospective analysis confirmed that auto- and allo-HSCT led to similar OS. The significantly lower incidence of relapse amongst allograft recipients was balanced by an increased incidence of death in CR.
Scanning Probe Microscopy: Delineating Structure-Property-Processing Relationships in Hybrid Organic/Inorganic Nanomaterials (2006)

Extended abstract of a paper presented at Microscopy and Microanalysis 2006 in Chicago, Illinois, USA, July 30 – August 3, 2005
The Study of the Kinetic Characteristics of Sorption of Scandium of Ion Exchanger Purolite MTS9580 from Return Circulating Solutions of Underground Leaching of Uranium Ores (2020)

This paper presents the results of a study of experiments on the sorption characteristics of phosphorus-containing ion exchangers Purolite MTS9580 (functional group ‒ derivatives of phosphonic acid) and Lewatit TP260 (functional group ‒ aminomethylphosphonic acid) on scandium. Using the method of low-temperature nitrogen adsorption, structural characteristics of selected ion exchangers Purolite MTS9580 and Lewatit TP260 respectively were measured. The specific surface of Purolite MTS9580 and Lewatit TP260 ion exchangers was measured as 5.1 and 4.5 m2/g, respectively. The obtained values indicate the presence of a macroporous structure in the ion exchangers. Experiments were carried out on the sorption of scandium and critical impurities in a static mode and dynamic mode while varying the acidity of the initial mother liquor of the sorption of uranium. Comparison of scandium sorption from pre-acidified uranium sorption mother liquor with Lewatit TP260 and Purolite MTS9580 ion exchangers showed an advantage for MTS9580 resin. The MTS9580 resin had an exchange capacity of 200 mg Sc/dm3 versus 59.7 mg Sc/dm3 for TP260. The dynamic exchange capacity of Purolite MTS9580 is much lower in relation to harmful impurities as Al, Fe, Ca, etc.