gebhart/patrepeval huggingface dataset:
<title>Nondestructive study of plastic pipe characteristics with double-pulse holographic interferometry</title> (1999)

In this paper we present the results of analytical study and experimental examination of long pipe oscillations. Two different approaches have been used for theoretical study, which are the Global Modal Analysis and direct solution of the wave equation for oscillating modes revealing and analysis of the displacement. The obtained results are compared with experimental data from pulse-laser holographic non-destructive testing of pipe vibration.
Estimating automobile chassis voltage distortion using load currents (2004)

This paper provides a model of the automobile chassis impedance for the purposes of predicting voltage distortion. A discrete-time model of the chassis and a method for identifying its parameters is introduced. The usefulness of the techniques developed in this paper are demonstrated using experimental data.
Growth of Low Basal Plane Dislocation Density SiC Epitaxial Layers (2006)

A method was developed in our laboratory to grow low basal plane dislocation (BPD) density and BPD-free SiC epilayers. The key approach is to subject the SiC substrates to defect preferential etching, followed by conventional epitaxial growth. It was found that the creation of BPD etch pits on the substrates can greatly enhance the conversion of BPDs to threading edge dislocations (TEDs) during epitaxy, and thus low BPD density and BPD-free SiC epilayers are obtained. The reason why BPD etch pits can promote the above conversion is discussed. The SiC epilayer growth by this method is very promising in overcoming forward voltage drop degradation of SiC PiN diodes.
Four-Phase High-Q Bandpass Filters (2013)

In the previous chapter, we saw that a simple passive mixer driven by 50% duty-cycle clocks converts a low-Q baseband impedance to a high-Q bandpass impedance through frequency translation. The center of this high-Q bandpass impedance is controlled precisely by the clock frequency, making it very attractive for reconfigurable receivers in which it is desirable to have high-Q bandpass filters with centers that can be tuned over a wide range of frequencies. Being implemented with just switches and capacitors, the resulting high-Q filter is exceptionally linear, and because the switches carry no DC, there is no major flicker noise issue. We saw, however, that this filter has the problem of image folding and cannot be useful in its current format. In this chapter, this filter evolves to a new high-Q bandpass filter that no longer folds the image. The resulting filter is still controlled by the clock frequency and is still composed of only switches and capacitors [23, 53, 54, 57–62]. The only complication of this evolved filter is the need for four arms of switches in series with baseband impedances plus a more complicated clocking scheme. The four-phase high-Q BPF requires four nonoverlapped 25% duty-cycle clocks that are progressively phase-shifted by 90°.
Interpretable Preference-based Reinforcement Learning with Tree-Structured Reward Functions (2021)

The potential of reinforcement learning (RL) to deliver aligned and performant agents is partially bottlenecked by the reward engineering problem. One alternative to heuristic trial-and-error is preference-based RL (PbRL), where a reward function is inferred from sparse human feedback. However, prior PbRL methods lack interpretability of the learned reward structure, which hampers the ability to assess robustness and alignment. We propose an online, active preference learning algorithm that constructs reward functions with the intrinsically interpretable, compositional structure of a tree. Using both synthetic and human-provided feedback, we demonstrate sample-efficient learning of tree-structured reward functions in several environments, then harness the enhanced interpretability to explore and debug for alignment.
Novel Routing Method Using Slime Mold Algorithm Corresponding to Movement of Content Source in Content-Oriented Networks (2019)

Content-oriented networks are proposed as a novel network architecture in which routing is conducted using the content ID instead of an IP address. In content-oriented networks, there is a problem that users cannot discover contents when the mobile communication device that has the contents moves about. Therefore, many studies have been undertaken to solve this problem. In conventional research, by applying ant colony optimization (ACO), Manome and Asaka tracked the movement of contents by adding a pheromone to the route of the mobile device itself. This method improved the discovery rate after movement compared with the case without the pheromone, indicating the effectiveness of their method. However, since the path searching by ACO depends on the behavior of movement of the mobile device, there is a problem of detouring along the route to the contents in some cases. To solve these problems, we used the true slime mold algorithm instead of ACO. In the simulation, we compared our results with those of the conventional method of using ACO to evaluate the performance of our proposed method.
Uptake of long-chain fatty acids in HepG2 cells involves caveolae (2002)

We investigated the role of caveolae in uptake and intracellular trafficking of long chain fatty acids (LCFA) in HepG2 human hepatoma cells. The uptake of [(3)H]oleic acid and [(3)H]stearic acid into HepG2 cells was measured by radioactive assays and internalization of the non-metabolizable fluorescent fatty acid 12-(N-methyl)-N-[(7-nitrobenz-2-oxa-1,3-diazol-4-yl)amino] (12-NBD) stearate into single HepG2 cells was semi-quantitatively assessed by laser scanning microscopy. The initial rate of [(3)H]oleic acid uptake (V(0)) in HepG2 cells exhibited saturable transport kinetics with increasing concentrations of free oleic acid (V(max) 854 +/- 46 pmol mg protein(-1) min(-1), K(m) 100 +/- 14 nmol/l). While inhibition of clathrin coated pits did not influence LCFA uptake in HepG2, inhibition of caveolae formation by filipin III, cyclodextrin, and caveolin-1 antisense oligonucleotides resulted in reduction of [(3)H]oleic acid uptake by 54%, 45%, and 23%, respectively. Furthermore, filipin III inhibited the uptake of [(3)H]stearic acid and its fluorescent derivative 12-NBD stearate by 44% and 50%, respectively. Transfection studies with alpha-caveolin-1/cyanofluorescent protein chimeras showed significant colocalization of caveolae and internalized 12-NBD stearate. In conclusion, these data suggest a significant role for caveolae mediated uptake and intracellular trafficking of LCFA in HepG2 cells.
Abstract 3977: Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells (2011)

Abstract Androgen receptor (AR) is expressed in all stages of prostate cancer progression and its levels increase in the castration-resistant tumors. However, the mechanisms regulating AR expression remain poorly understood. Here, our aim was to determine the role of miRNAs in regulating AR protein. To this end, we performed a systematic gain-of function screen for 1129 miRNA molecules in prostate cancer cell lines and quantified changes in AR protein content using protein lysate microarrays. We identified 71 unique miRNAs that influenced the level of AR in LNCaP, LAPC-4, 22Rv1, CWR-1R and MDA-PCa-2B cells. Our RNA-sequencing data showed that the 3’UTRs of many genes, including the AR, are much longer than currently used by target prediction programs. Our analyses predicted that the majority of the miRNA regulation of AR would occur through the extended 6 kb 3’UTR. 3’UTR-binding assays validated 13 miRNAs (miR-135b, miR-185, miR-297, miR-299-3p, miR-34a, miR-34c, miR-371-3p, miR-421, miR-449a, miR-449b, miR-634, miR-654-5p, and miR-9) as direct AR regulators. Fifteen AR down-regulating miRNAs decreased androgen-induced proliferation of prostate cancer cells in vitro. Negative correlation of miR-34a and miR-34c expression with AR levels was also found in clinical prostate cancers. To conclude, our results demonstrate that miRNAs interacting with the long 3’UTR of the AR gene are important regulators of AR protein levels. This could be applied for developing novel therapeutic strategies to inhibit AR function and androgen-dependent cell growth. Citation Format: {Authors}. {Abstract title} [abstract]. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2-6; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2011;71(8 Suppl):Abstract nr 3977. doi:10.1158/1538-7445.AM2011-3977
Reductive activation of diaziquone and possible involvement of free radicals and the hydroquinone dianion. (1986)

To analyze the mode of action of diaziquone [AZQ] on DNA, we examined the activity of two AZQ analogues and N,N',N"-triethylenethiophosphoramide on three forms [supercoiled (Form I), open circular (Form II), and linear (Form III)] of PM-2 DNA. The AZQ analogues contained chlorine atoms which substituted either the carbethoxyamino groups or the aziridine groups of the parent compound. N,N',N"-triethylenethiophosphoramide is a triaziridine compound containing pentavalent phosphorus instead of a quinone group. We found that only when reduced with sodium borohydride did AZQ change the topology of the three forms of PM-2 DNA by introducing mainly single strand breaks. The AZQ analogue containing only aziridines (RQ2) was active in both its oxidized and its reduced forms, while the analogue containing only the carbethoxyamino groups (RQ14) or N,N',N"-triethylenethiophosphoramide were not active in either form. Under similar experimental conditions, Adriamycin alone altered the electrophoretic mobility of PM-2 DNA, while borohydride reduced Adriamycin did not. By using electron spin resonance spectroscopy, we showed that dihydrodiaziquone (AZQH2) oxidizes to the semiquinone in the presence of oxygen. Although AZQH2 was active against DNA, it was not active against cellular DNA synthesis as measured by [3H]thymidine incorporation into exponentially growing HEp-2 cells. However, AZQ alone prevented [3H]thymidine incorporation into HEp-2 cells. We found that HEp-2 cells have the ability to reduce AZQ to its free radical anion, but AZQH2 does not autoxidize to the free radical in the presence of cells. The reductive ability of HEp-2 cells may be responsible in part for preventing the oxidation of AZQH2 to the free radical. We found that under our conditions (1-h incubations) the aziridines are essential for the activity of aziridinyl quinones against PM-2 DNA and that in the case of AZQ the hydroquinone is also required.
Binder-free three-dimensional high energy density electrodes for ionic-liquid supercapacitors (2015)

We demonstrate a facile methodology to fabricate binder-free porous carbon nanofiber electrodes for room temperature ionic-liquid supercapacitors. The device provides an energy density of 80 W h kg(-1) based on the mass of two electrodes while retaining the high rate capability of supercapacitors with near-ideal CV curves at a high scan rate of 200 mV s(-1).
Acidic macromolecules associated with the mineral phase of scleractinian coral skeletons (1988)

Abstract Macromolecules intimately associated with the mineral phase of two species of scleractinian coral skeletons are extracted in different ways and partially characterized in some detail for the first time. They are shown to contain an assemblage of glycoproteins in which the protein moiety is rich in acidic amino acids and the carbohydrate moiety contains sulfated polysaccharides. In the presence of calcium, the proteins partially adopt the β‐sheet conformation. The properties of these macromolecules are all consistent with their fulfilling some as yet unidentified roles in controlling mineralization. Furthermore, their properties are similar in many respects to macromolecules present in the mineralized tissues of diverse organisms.
Theoretical analysis and range of validity of TSA formulation for application to UXO discrimination (2004)

Operating in the magnetoquasistatic regime (a few hertz to perhaps a few 100 kHz), electromagnetic induction (EMI) sensing has recently emerged as one of the most promising avenues for discrimination of subsurface metallic objects, e.g., unexploded ordnance. The technique of thin-skin approximation (TSA) was devised to deal with numerical problems caused by the rapid decay of fields beneath the scatterer's surface. The rather nonintuitively broad applicability and specific error patterns of the TSA formulation are explained here by theoretical analysis based on analytical solutions and approximate Monte Carlo simulation. In the limiting case of infinitesimal skin depth (EMI perfect reflection), the scatterer aspect ratio (AR) is inferred without regard to metal type. Alternatively, the AR of some homogeneous magnetic objects is inferred from the pattern of transverse to axial response ratio over the entire EMI ultrawideband. Use of the method in inversions for electromagnetic parameters reveals fundamental nonuniqueness problems and shows their basis, which is not dependent on the method of forward solution.
Optimal design of a salient poles permanent magnet synchronous motor using geometric programming and finite element method (2008)

An optimal design of a salient poles permanent magnets synchronous motor is presented. Firstly, a multivariable optimization process is performed by geometric programming method in order to minimize the total cost of the motor. Then a finite element method is used to evaluate recursively the motor torque. This methodology is applied to the optimal design of a three-phase, 5 Hp, 1800 rpm salient poles permanent magnet motor. The results show that the proposed methodology is fast and reliable and allows obtaining a very accurate torque evaluation and a great flexibility to observe how the motor optimal design varies with the specifications.
Free-Radical Hydrosilylation of Poly(phenylsilane): Synthesis of Functional Polysilanes (1994)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTFree-Radical Hydrosilylation of Poly(phenylsilane): Synthesis of Functional PolysilanesYu-Ling Hsiao and Robert M. WaymouthCite this: J. Am. Chem. Soc. 1994, 116, 21, 9779–9780Publication Date (Print):October 1, 1994Publication History Published online1 May 2002Published inissue 1 October 1994https://pubs.acs.org/doi/10.1021/ja00100a065https://doi.org/10.1021/ja00100a065research-articleACS PublicationsRequest reuse permissionsArticle Views714Altmetric-Citations91LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (2)»Supporting Information Supporting Information Get e-Alerts
Optimum Conditions for the Formation of Ammonia as a Precursor of Tetramethylpyrazine by Lactococcus lactis ssp. lactis biovar. diacetilactis FC1 (1991)

To investigate the optimum conditions for the production of ammonia as a precursor of tetramethylpyrazine flavor compound from arginine by Lactococcus lactis ssp. lactis biovar. diacetilactis FC1, fermentation factors such as initial pH of culture media, fermentation temperature, concentration of arginine-HC1, and sugars were examined. The optimum conditions were initial pH 5.5 of the culture media, fermentation temperature of , 6% (w/v) of arginine-HC1, and 1% (w/v) of galactose as a carbon source. Under the optimum fermentation conditions, 40 mmole/l of ammonia was produced after 40 h.
Perovskite Core–Shell Nanowire Transistors: Interfacial Transfer Doping and Surface Passivation (2020)

While halide perovskite electronics are rapidly developing, they are greatly limited by the inferior charge transport and poor stability. In this work, effective surface charge transfer doping of vapor-liquid-solid (VLS)-grown single-crystalline cesium lead bromide perovskite (CsPbBr<sub>3</sub>) nanowires (NWs) <i>via</i> molybdenum trioxide (MoO<sub>3</sub>) surface functionalization is achieved. Once fabricated into NW devices, due to the efficient interfacial charge transfer and reduced impurity scattering, a 15× increase in the field-effect hole mobility (μ<sub>h</sub>) from 1.5 to 23.3 cm<sup>2</sup>/(V s) is accomplished after depositing the 10 nm thick MoO<sub>3</sub> shell. This enhanced mobility is already better than any mobility value reported for perovskite field-effect transistors (FETs) to date. The photodetection performance of these CsPbBr<sub>3</sub>/MoO<sub>3</sub> core-shell NWs is also investigated to yield a superior responsivity (<i>R</i>) up to 2.36 × 10<sup>3</sup> A/W and an external quantum efficiency (EQE) of over 5.48 × 10<sup>5</sup>% toward the 532 nm regime. Importantly, the MoO<sub>3</sub> shell can provide excellent surface passivation to the CsPbBr<sub>3</sub> NW core that minimizes the diffusion of detrimental water and oxygen molecules, improving the air stability of CsPbBr<sub>3</sub>/MoO<sub>3</sub> core-shell NW devices. All these findings evidently demonstrate the surface doping as an enabling technology to realize high-mobility and air-stable low-dimensional halide perovskite devices.
2-Deoxystreptamine:  Central Scaffold of Aminoglycoside Antibiotics (2005)

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mpiQulacs: A Distributed Quantum Computer Simulator for A64FX-based Cluster Systems (2022)

Quantum computer simulators running on classical computers are essential for developing real quantum computers and emerging quantum applications. In particular, state vector simulators, which store a full state vector in memory and update it in every quantum operation, are available to simulate an arbitrary form of quantum circuits, debug quantum applications, and validate future quantum computers. However, the time and space complexity grows exponentially with the number of qubits and easily exceeds the capability of a single machine. Therefore, we develop a distributed state vector simulator, $mpiQulacs$, that is optimized for large-scale simulation on A64FX-based cluster systems. A64FX is an ARM-based CPU that is also equipped in the world's top Fugaku supercomputer. We evaluate weak and strong scaling of mpiQulacs with up to 36 qubits on a new 64-node A64FX-based cluster system named $Todoroki$. By comparing mpiQulacs with existing distributed state vector simulators, we show that mpiQulacs achieves the highest performance for large-scale simulation on tens of nodes while sustaining a nearly ideal scalability. Besides, we define a new metric, $quantum B/F ratio$, and use it to demonstrate that mpiQulacs running on Todoroki fits the requirements of distributed state vector simulation rather than the existing simulators running on general purpose CPU-based or GPU-based cluster systems.
Preparation of genetically engineered A/H5N1 and A/H7N1 pandemic vaccine viruses by reverse genetics in a mixture of Vero and chicken embryo cells (2007)

The seeds obtained could be used as part of a pandemic vaccine strain 'library' available in case of propagation in humans of a new highly pathogenic avian strain.
Constraint Design and Modelling of Multi-Hop Multi-Band Wireless MIMO Networks (2008)

Recent technological advances have enabled SDRs to switch from one frequency band to another at minimum cost, thereby making dynamic multi-band access and sharing possible. On the other hand, recent advances in signal processing combined with those in antenna technology provide MIMO capabilities, thereby creating opportunities for enhancing the throughput of wireless networks. Both SDRs and MIMO together enable next-generation wireless networks, such as mesh networks, to support dynamic and adaptive bandwidth sharing along time, frequency, and space. In this paper, we design and model the radio and interference constraints on multi-hop wireless networks when they are both SDR-capable and MIMO-equipped. The developed constraint models can be used for a variety of networking applications, such as network performance evaluation, routing algorithms, and admission control and QoS mechanisms.
Theoretical study of B2H+5, B2H+6, and B2H6 (1988)

A theoretical study is presented of B2H+5,B2H+6, and B2H6 at a high level of theory, including correlation energy beyond fourth-order perturbation theory and large basis sets. The B2H+5 ion is predicted to have a triply hydrogen-bridged structure, with a calculated appearance potential in agreement with a recently measured value by photoionization. The most stable B2H+6 ion found corresponds to a very weakly bound complex between B2H+5 and H, likely to exist only in a metastable state.
Future prospects in prostate cancer (1999)

To this aim, refinement of surgical approaches, with appropriate adjuvant therapies, will ensure more complete cancer control, while minimizing associated morbidity. New delivery systems for radiotherapy, as well as other energy sources, are evolving, while a number of promising pharmacological agents, including angiogenesis inhibitors and drugs which alter signal transduction pathways, are currently under investigation. Early detection is also being facilitated by a more widespread implementation of screening programs. Advances in tumor markers, and imaging and biopsy techniques, will allow more accurate preoperative staging. These, coupled with improvements in prognostic markers, aid the physician and patient alike in deciding on the suitability of treatment options with better estimation of outcome. Perhaps the most exciting developments in prostate cancer will come from knowledge of the molecular mechanisms underlying carcinogenesis. The potential for the development of diagnostic and therapeutic tools is immense. The efficacy of treatment can be studied at a molecular level, and strategies for preventing or slowing the development of malignancy can be formulated. RESULTS AND CONCLUSIONS Application of this knowledge in the form of gene and cellular therapy and in the development of novel systemic agents is beginning to enter the realm of clinical practice, and it may be in this field that means for cure and prevention of prostate cancer will eventually be found.