gebhart/patrepeval huggingface dataset:
Enseñanza de programación orientada a objetos mediante el desarrollo de aplicaciones gráficas interactivas (1970)

En la asignatura de Informatica Industrial de la EUITI-UPM se ha optado por desarrollar un metodo docente basado en el diseno y desarrollo de una aplicacion grafica interactiva como son los videojuegos, los simuladores o herramientas de ingenieria. L
ChemInform Abstract: CHEMIE GESPANNTER BINDUNGEN 36. MITT. PHOTOLYSE VON SUBSTITUIERTEN 2,3‐DIAZA‐BICYCLO(3,1,0)HEXEN‐(2)‐DERIVATEN, EINFACHER WEG ZU BICYCLO(1,1,0)BUTANEN (1973)

Abstract Die Diazabicyclohexene (I), die aus dem entsprechenden Cyclopropen und Diphenyldiazomethan dargestellt werden (Ausbeute 90‐99%), ergeben nach 12stündiger Photolyse in Pentan die Bicyclobutane (III) sowie die Olefine (IV).
Carrier transport effects in high-speed quantum-well lasers (1992)

ABSTRACT Carrier transport can significantly affect the high speed propeities of quantum well lasers. We have &xeloped amodel, and derived analytical expressions for the modulation response, resonance frequency, damping rale and K fftw toinclude these effects. We show theoretically and expenmentally that carrier transport can lead to significan low frequency parasitic-like rolloff that reduces the modulation response by as much as a ftor of six in quantum well 1ars. We also show that, in addition, it leads to a reduction in the effective differential gain and thus the resonance frequency, while thenonlinear gain compression ftor remains largely unaffected by it. In the presence of significant transport effects, we show that the real limit to the maximum possible modulation bandwidth is much lower than the one predicted by the K factor alone. 1. INTRODUCTION Quantum well lasers have been theoretically and experimentally shown to have a larger differential gain than bulklasers1 , but the modulation bandwidths reported in quantum well lasers have only recently been comparable to bulk
Grating-based ultra-compact SWNIR spectral sensor head developed through MOEMS technology (2019)

A grating-based ultra-compact spectral sensor head was developed to overcome obstacles in characteristics, cost, and size, and it was designed for commercialization in large volume applications. More and more compact spectrometers have been brought to market in recent years—for example, those used for food and beverage quality tests based on measuring sugar content—but their spread is still limited because the conventional types don’t fully fulfill the market requirements. The ultra-compact spectral sensor’s characteristics have been improved while reducing cost and size. Its 20 nm wavelength resolution, equivalent to that of conventional compact spectrometers, was made possible by applying multiplex reflection and small collimation. Using nano-imprint technology, a grating was replicated onto a concave surface inside a compact surface-mount device package. On the opposite side of the concave grating, an entrance slit and a mirror that directs light onto the grating were directly formed on a high-sensitivity CMOS linear image sensor that is sensitive to the 640-1050nm range. The 15&mu;m wide entrance slit was formed on the CMOS silicon chip using MEMS technology, and a short-wavelength cut filter was attached to the entrance window. By reducing the number of components, the structure was simplified. An ultra-compact package measuring 11.7mm &times; 4mm &times; 3.05mm and weighing about 0.3g is made possible while maintaining good characteristics and reasonable cost.
High-salt intake affects retinal vascular tortuosity in healthy males: an exploratory randomized cross-over trial (2021)

The retinal microcirculation is increasingly receiving credit as a relatively easily accessible microcirculatory bed that correlates closely with clinical cardiovascular outcomes. The effect of high salt (NaCl) intake on the retinal microcirculation is currently unknown. Therefore, we performed an exploratory randomized cross-over dietary intervention study in 18 healthy males. All subjects adhered to a two-week high-salt diet and low-salt diet, in randomized order, after which fundus photographs were taken and assessed using a semi-automated computer-assisted program (SIVA, version 4.0). Outcome parameters involved retinal venular and arteriolar tortuosity, vessel diameter, branching angle and fractal dimension. At baseline, participants had a mean (SD) age of 29.8 (4.4) years and blood pressure of 117 (9)/73 (5) mmHg. Overall, high-salt diet significantly increased venular tortuosity (12.2%, p = 0.001). Other retinal parameters were not significantly different between diets. Changes in arteriolar tortuosity correlated with changes in ambulatory systolic blood pressure (r = - 0.513; p = 0.04). In conclusion, high-salt diet increases retinal venular tortuosity, and salt-induced increases in ambulatory systolic blood pressure associate with decreases in retinal arteriolar tortuosity. Besides potential eye-specific consequences, both phenomena have previously been associated with hypertension and other cardiovascular risk factors, underlining the deleterious microcirculatory effects of high salt intake.
Performance of a Chromatic Adaptation Transform based on Spectral Sharpening (2000)

The Bradford chromatic adaptation transform, empirically derived by Lam, models illumination change. Specifically, it provides a means of mapping XYZs under a reference light source to XYZs for a target light source such that the corresponding XYZs produce the same perceived color.One implication of the Bradford chromatic adaptation transform is that color correction for illumination takes place not in cone space but rather in a &#x2018;narrowed&#x2019; cone space. The Bradford sensors have their sensitivity more narrowly concentrated than the cones. However, Bradford sensors are not optimally narrow. Indeed, recent work has shown that it is possible to sharpen sensors to a much greater extent than Bradford.The focus of this paper is comparing the perceptual error between actual appearance and predicted appearance of a color under different illuminants, since it is perceptual error that the Bradford transform minimizes. Lam's original experiments are revisited and perceptual performance of the Bradford transform and linearized Bradford transform is compared with that of a new adaptation transform that is based on sharp sensors. Perceptual errors in CIELAB &#x394;E, &#x394;ECIE94, and &#x394;ECMC(1:1) are calculated for several corresponding color data sets and analyzed for their statistical significance. The results are found to be similar for the two transforms, with Bradford performing slightly better depending on the data set and color difference metric used. The sharp transform performs equally well as the linearized Bradford transform: there is no statistically significant difference in performance for most data sets.
Checklists and Other Cognitive Aids For Emergency And Routine Anesthesia Care-A Survey on the Perception of Anesthesia Providers From a Large Academic US Institution (2015)

Providers at our large academic institution generally embrace the concept of checklists and other cognitive aids. This was true for all providers for checklists for procedural time outs, anesthesia crisis situations and those for routine procedures that providers rarely perform. Only very experienced and very junior providers appreciated the use of checklists for routine care. There remains a discrepancy between these claims and provider's perception on their clinical competency based on memory alone.
Generation of a Squeezed Vacuum field with PPKTP at 1064nm for Gravitational Wave Interferometers (2007)

Squeezed vacuum generation at 1064 nm in a PPKTP-based optical parametric oscillator is demonstrated for sensitivity improvements in gravitational wave detectors. Broadband squeezing of &gt;2.5dB is reported in the 1-100 KHz frequency range.
A Router Architecture for Connection-Oriented Service Guarantees in the MANGO Clockless Network-on-Chip (2005)

Submitted on behalf of EDAA (http://www.edaa.com/)
Immunochromatography on insolubilized antibodies of very low affinity: application to immunoadsorbence of bovine alpha-fetoprotein. (1978)

Cross-reactive antibodies were utilized to prepare immunoadsorbents possessing a very low affinity to bovine alpha-fetoprotein (AFP). A goat anti-human AFP serum cross-reactive with bovine AFP was first depleted of antibodies reactive with bovine AFP in immunodiffusion. The remaining antibodies from this serum and gamma-globulin from a sheep antiserum against rabbit AFP, without prior absorption, were coupled to Sepharose. Chromatography of fetal calf serum on these adsorbents resulted in retardation of bovine AFP relative to other proteins. A major part of the AFP eluted from the columns with phosphate-buffered saline. The rest eluted as a sharp peak with a small quantity of 4 or 6 M urea. The elution of AFP with the initial column buffer has made it possible to prepare pure AFP that has not been subjected to the chaotropic elution buffers usually employed in affinity chromatography. Elimination of the washing step and the ease of elution has allowed purification of gram amounts of AFP. The fact that immunoadsorbents prepared from antibodies with no detectable reactivity in immunodiffusion still caused delayed elution in chromatography suggests that this procedure may be useful in search of proteins cross-reactive with a known protein.
Signals for activation and proliferation of murine T lymphocyte clones. (1987)

Biochemical signals required for the growth of T cell clones were studied. Antigen-specific helper T cell clones, 6-1 and KO.6, could enter the state similar to the resting state where the cells expressed only small numbers of interleukin 2 (IL2) receptors and could not respond to IL2 without antigenic stimulation. A combination of a phorbol ester, 12-O-tetradecanoylphorbol-13-acetate (TPA), and a calcium ionophore, A23187, induced the expression of IL2 receptors on resting 6-1 cells and induced DNA synthesis in the presence of IL2. TPA alone did not induce IL2 receptors. A23187 induced the expression of the receptors to some extent but did not induce DNA synthesis even in the presence of IL2. IL2 receptors induced by A23187 alone were mostly low affinity receptors, whereas the combination of TPA and A23187 induced high affinity receptors in addition to low affinity receptors. Resting KO.6 cells produced IL2 in response to a combination of TPA and A23187, whereas either one of the agents did not induce the production of IL2. Dicaprylin, a permeable diacylglycerol and a potent activator of protein kinase C (the Ca2+/phospholipid-dependent enzyme) could replace TPA in both cases when dicaprylin was repeatedly added to the culture. These results suggest that strong and continuous activation of protein kinase C together with calcium mobilization is required for IL2 production and IL2 receptor expression. On the contrary, signals for DNA synthesis generated by binding of IL2 to IL2 receptors are different from those for IL2 production and IL2 receptor expression, as the combination of TPA and A23187 could not induce DNA synthesis without IL2.
An Astonishing Resemblance with the Photo-Oxidative Analogue* (2006)

Cyclic voltammetry (CV), rotating disk electrode voltammetry (RDE) and bulk electrolysis were used to investigate the electrochemical oxidation of the title cluster in acetonitrile (CH3CN). Two irreversible 2-electron oxidation processes occur at +0.95 V and +1.15 V vs. SCE. Bulk electrolysis demonstrates that the d–d Pd2(dppm)2(NCCH3)2 2+ 4 complex is generated among the first intermediates, and the d Pd(dppm)(NCCH3)2 2+ 3 is formed as the final product. The intermediacy of ‘‘Pd3(dppm)3(CO) ’’ and ‘‘Pd3(dppm)3 ’’ is suspected but not confirmed. This oxidation process exhibits a close resemblance to the photo oxidative reactivity of the title cluster in the presence of chlorocarbons (R–Cl) for which the sole observed product is Pd(dppm)Cl2.
Superantigen-Mediated Encephalitis (2011)

Encephalitis may result from the interaction between a pathogen and the host brain, such as in bacterial, viral or fungal infection of the CNS. There are, however, different states of aseptic encephalitis, which may be induced e.g. by way of (i) self-directed immune attacks as in experimental autoimmune encephalomyelitis or (ii) by certain substances like the copper chelating agent cuprizone (Torkildsen et al., 2008). In fact, in encephalitis, infectious and non-infectious processes do not mutually exclude each other. Many pathogens such as bacteria or viruses encode for immune stimulating peptides, better known as superantigens for their enormous potency to stimulate immune cells (Kappler et al., 1989; Fleischer, 1991). T-cell superantigens have been developed twice during the evolution, namely independently by bacteria and by viruses. Not all bacteria or viruses do, however, possess a superantigen. Superantigens act in a T-cell receptor V(beta) dependent manner (Figure 1). Thereby, up to 10% or even 20% of the T-cell repertoire may become activated, sometimes resulting in a fulminant inflammatory response. The latter depends also on the specific repertoire of the host’s antigen-detection apparatus, e.g., the human-leucocyte-antigen (HLA) molecules.
The TASCC of Secretion (2011)

Author Manuscript 2012 July 05
Lack of unusual longevity in Vilcabamba, Ecuador. (1982)

Mortality records from the supposedly longevous population of Vilcabamba in southern Ecuador were evaluated for the period 1907 through 1979. Records from the [nearby] urban center of Loja were also recorded. These records were used to calculate life expectancy tables using a revision of the synthetic cohort method that involved reverse summation. Age at death was corrected for the prevalent age exaggeration using a regression previously established for this community. Life expectancy has increased somewhat in Vilcabamba over the past 70 years. Age exaggeration was evident in the mortality records throughout this period indicating that this behavioral pattern was not a result of recent publicity. Age exaggeration was responsible for all evidence of increased longevity in the life tables compared to U.S. values....This evidence together with the documented exaggeration in centenarians and the debunking of the demographic claims provides the final link in showing no unusual longevity in this population. (EXCERPT)
Dynamic RRH Clustering using Affinity Propagation Algorithm in Ultra-Dense C-RAN (2020)

Joint transmission across the cluster of radio remote heads (RRHs) by exploiting the centralized processing of the cloud-radio access network (C-RAN) is a promising technique to overcome the severe interference problems in ultra-dense small cell networks. In practical considerations, local clustering of networks is preferred over global clustering as the number of RRHs that can be jointly transmitted on the network is finite. In this study, we attempt to revisit the principles of the well-known affinity propagation (AP) clustering algorithms, especially for the naive method of determining the exemplar with a fixed threshold. To further explain the decision method, we propose a method to easily determine the threshold using the network map of converged value of messages generated by AP algorithm, by combining Otsu's threshold and density peak searching method with the existing AP clustering algorithm. The proposed algorithm provides higher spectral efficiency than the conventional AP algorithms as well as statically coordinated multi-point (CoMP) techniques, although it has similar execution time as the traditional AP algorithms.
Oncogenic All1 fusion proteins target Drosha-mediated microRNA processing (2007)

MicroRNAs (miRNAs) are noncoding small RNA of approximately 22 bases, which suppress expression of target genes through translational block or degradation of a target's transcript. Recent studies uncovered specific miRNA expression profiles in human malignancies. Nevertheless, the mechanisms underlying cancer-specific miRNA expression are largely unknown. miRNA biogenesis consists of a series of steps beginning with generation of a primary transcript, termed pri-miRNA, and continuing into excision of a stem-loop hairpin structure within pri-miRNA by the nuclear RNaseIII enzyme Drosha, transportation to the cytoplasm, and further processing by a second RNaseIII enzyme Dicer, into a 22-base mature duplex RNA. In principle, alteration in any step during this maturation process could affect miRNA production. The ALL-1 (also termed MLL) gene was originally isolated by virtue of its involvement in recurrent chromosome translocations associated with acute leukemias, particularly in infant and therapy-related leukemias. These translocations result in the fusion of ALL-1 with partner genes and the consequent production of chimeric leukemogenic proteins. Here, we identify specific miRNAs up-regulated in leukemias triggered by All1 fusions. Further, we demonstrate coimmunoprecipitation of the All1/Af4 and All1/Af9 fusions with Drosha, disrupted by treatment with DNase I. Finally, we present evidence from ChIP experiments for All1 fusion protein-mediated recruitment of Drosha to target genes encoding miRNAs. Such recruitment may underlie the enhanced expression of the relevant miRNAs.
Autonomic innervation of the carotid body as a determinant of its sensitivity: implications for cardiovascular physiology and pathology (2020)

The motivation for this review comes from the emerging complexity of the autonomic innervation of the carotid body (CB) and its putative role in regulating chemoreceptor sensitivity. With the carotid bodies as a potential therapeutic target for numerous cardiorespiratory and metabolic diseases, an understanding of the neural control of its circulation is most relevant. Since nerve fibres track blood vessels and receive autonomic innervation, we initiate our review by describing the origins of arterial feed to the CB and its unique vascular architecture and blood flow. Arterial feed(s) vary amongst species and, unequivocally, the arterial blood supply is relatively high to this organ. The vasculature appears to form separate circuits inside the CB with one having arterial venous anastomoses. Both sympathetic and parasympathetic nerves are present with postganglionic neurons located within the CB or close to it in the form of paraganglia. Their role in arterial vascular resistance control is described as is how CB blood flow relates to carotid sinus afferent activity. We discuss non-vascular targets of autonomic nerves, their possible role in controlling glomus cell activity, and how certain transmitters may relate to function. We propose that the autonomic nerves sub-serving the CB provide a rapid mechanism to tune the gain of peripheral chemoreflex sensitivity based on alterations in blood flow and oxygen delivery, and might provide future therapeutic targets. However, there remain a number of unknowns regarding these mechanisms that require further research that is discussed.
Lens-free Microscopy Using Acoustically Actuated Nanolenses and its Applications (2019)

Integration of acoustically actuated nanolenses into a lens-free microscopy enables a cost-effective platform for detection of nanoparticles and nanoliter volume rheology. We demonstrate the detection of single nanoparticles and the rheological analysis of viscoelastic fluids.
Experimental Realization of Subradiant, Superradiant, and Fano Resonances in Ring/Disk Plasmonic Nanocavities (2010)

Subradiant and superradiant plasmon modes in concentric ring/disk nanocavities are experimentally observed. The subradiance is obtained through an overall reduction of the total dipole moment of the hybridized mode due to antisymmetric coupling of the dipole moments of the parent plasmons. Multiple Fano resonances appear within the superradiant continuum when structural symmetry is broken via a nanometric displacement of the disk, due to coupling with higher order ring modes. Both subradiant modes and Fano resonances exhibit substantial reductions in line width compared to the parent plasmon resonances, opening up possibilities in optical and near IR sensing via plasmon line shape design.
SENSORY INFORMATION PROCESSING BY NOISY BISTABLE NEURONS (1992)

Many neurons in the central nervous system and at the sensory periphery receive periodic input. The neural activity of interest here is one which may be called "statistical phase-locking", where the neuron fires preferentially near a given phase of the stimulus, but skips a random number of stimulus cycles between successive firings. It is shown that intervals between successive firings are distributed according to the same density as that of residence times in bistable noisy systems, provided these times are computed from suitably chosen interwell transitions. This brief review further makes this connection plausible by relating properties of neurons to those of bistable systems. Further it looks at the question of what role noise and possibly stochastic resonance, which can arise in this context, may play in information processing at the sensory neuron level.
ChemInform Abstract: Heterogeneous Catalysis of the Friedel‐Crafts Alkylation by Doped Natural Phosphate and Tricalcium Phosphate. (1996)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Phase Change Memory technology for embedded non volatile memory applications for 90nm and beyond (2009)

A 90 nm embedded PCM technology is presented. For the first time the storage element has been integrated in a 6-ML advanced CMOS platform, exploiting the LV n-mos device as cell selector. Very good cell working window and intrinsic reliability both for storage element and selector MOS have been proven. The full integration of a 4 Mb ePCM macrocell with very few additional masks and minimal process tuning confirms this technology as a viable solution for floating gate non-volatile memory replacement in embedded applications.
Sky Segmentation for Enhanced Depth Reconstruction and Bokeh Rendering with Efficient Architectures (2020)

We present a high-quality sky segmentation model for depth refinement and investigate residual architecture performance to inform optimally shrinking the network. We describe a model that runs in near real-time on mobile device, present a new, highquality dataset, and detail a unique weighing to trade off false positives and false negatives in binary classifiers. We show how the optimizations improve bokeh rendering by correcting stereo depth misprediction in sky regions. We detail techniques used to preserve edges, reject false positives, and ensure generalization to the diversity of sky scenes. Finally, we present a compact model and compare performance of four popular residual architectures (ShuffleNet, MobileNetV2, Resnet-101, and Resnet-34-like) at constant computational cost.
Table S4 from JQ1 Induces DNA Damage and Apoptosis, and Inhibits Tumor Growth in a Patient-Derived Xenograft Model of Cholangiocarcinoma (2023)

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