gebhart/patrepeval huggingface dataset:
NPRportrait 1.0: A Three-Level Benchmark for Non-Photorealistic Rendering of Portraits (2020)

Despite the recent upsurge of activity in image-based non-photorealistic rendering (NPR), and in particular portrait image stylisation, due to the advent of neural style transfer, the state of performance evaluation in this field is limited, especially compared to the norms in the computer vision and machine learning communities. Unfortunately, the task of evaluating image stylisation is thus far not well defined, since it involves subjective, perceptual and aesthetic aspects. To make progress towards a solution, this paper proposes a new structured, three level, benchmark dataset for the evaluation of stylised portrait images. Rigorous criteria were used for its construction, and its consistency was validated by user studies. Moreover, a new methodology has been developed for evaluating portrait stylisation algorithms, which makes use of the different benchmark levels as well as annotations provided by user studies regarding the characteristics of the faces. We perform evaluation for a wide variety of image stylisation methods (both portrait-specific and general purpose, and also both traditional NPR approaches and neural style transfer) using the new benchmark dataset.
Supplementary Figures and Table with legends from Predictive Signatures Inform the Effective Repurposing of Decitabine to Treat KRAS–Dependent Pancreatic Ductal Adenocarcinoma (2023)

&lt;p&gt;Supplementary Figures and Table with legends&lt;/p&gt;
Double exposure double etch for dense SRAM: a designer's dream (2008)

As SRAM arrays become lithographically more aggressive than random logic, they are more and more determining the lithography processes used. High yielding, low leakage, dense SRAM cells demand fairly aggressive lithographic process conditions. This leads to a borderline process window for logic devices. The tradeoff obtained between process window optimization for random logic gates and dense SRAM is not always straightforward, and sometimes necessitates design rule and layout modifications. By delinking patterning of the logic devices from SRAM, one can optimize the patterning processes for these devices independently. This can be achieved by a special double patterning technique that employs a combination of double exposure and double etch (DE2). In this paper we show how a DE2 patterning process can be employed to pattern dense SRAM cells in the 45nm node on fully integrated wafers, with more than adequate overlap of gate line-end onto active area. We have demonstrated that this process has adequate process window for sustainable manufacturing. For comparison purpose we also demonstrate a single exposure single etch solution to treat such dense SRAM cells. In 45nm node, the dense SRAM cell can also be printed with adequate tolerances and process window with single expose (SE) with optimized OPC. This is confirmed by electrical results on wafer. We conclude that DE2 offers an attractive alternative solution to pattern dense SRAM in 45nm and show such a scheme can be extended to 32nm and beyond. Employing DE2 lets designers migrate to very small tip-to-tip distance in SRAM. The selection of DE2 or SE depends on layout, device performance requirements, integration schemes and cost of ownership.
Electric Field Emission of High Density O[sup −] Ions from 12CaO⋅7Al[sub 2]O[sub 3] Engineered to Incorporate Oxygen Radicals (2002)

We succeeded in extracting intense ion beam by applying dc voltage to a microporous crystal (C12A7) engineered to incorporate extremely large amounts of and in crystallographic cages. The ion beam is monochromatic and the current density (∼2 μA/cm2) is higher by three orders of magnitude than the maximum value recorded for yttrium-stabilized (YSZ). A surface metal electrode, essential for the YSZ to dissociate a drifted in the bulk into an and an electron on the surface, is not needed for the C12A7. The presence of extremely large concentrations of and ions and fast oxygen-ion-conductive nature of C12A7 allow extraction of ions directly from the surface. © 2002 The Electrochemical Society. All rights reserved.
A Maturation Process or Binders Based on Coordination Chemistry to Boost the Mechanical Strength and Cyclability of Si-Based Electrodes (2020)

Silicon is attractive as negative electrode material for Li-ion batteries (LIBs) to increase their energy density [1]. The main challenge is to deal with the large silicon volume expansion induced by its lithiation, which damages the mechanical integrity of the electrode, and produces an unstable solid electrolyte interphase (SEI). Recently, we have discovered a post-processing treatment, called maturation, which very significantly improves the mechanical and electrochemical stabilities of silicon-based electrodes made with polycarboxylic acid binders [2-4]. It consists of storing the electrode in a humid atmosphere for a few days before drying and cell assembly. We found that during maturation, the atmospheric-induced corrosion of the current collector releases oxidized copper species that migrate into the electrode to physically crosslink the binder phase, substantially modifying its resiliency to the silicon volume variation as shown by various in situ and operando characterizations. The pre-addition of a small amount of copper or zinc salt in the electrode slurry allows to reach similar improvement of electrochemical performance than maturation [5]. This reveals that there is great potential to explore coordination chemistry to design new, more efficient binders through the medium strength and dynamic nature of coordination bonds [6]. Acknowledgments The authors thank the Natural Sciences and Engineering Research Council of Canada (NSERC) (grant RGPIN-2016-04524) and Transition Énergétique Québec (TEQ) (grant Techno-0040-0001) for financial support of this work. References [1] M.N. Obrovac, Si-alloy negative electrodes for Li-ion batteries. Current Opinion in Electrochemistr, 2018, 9, 8–17. [2] Z. Karkar et al., How silicon electrodes can be calendered without altering their mechanical strength and cycle life J. Power Sources, 2017, 371, 136-147. [3] C. Real Hernandez et al., A Facile and Very Effective Method to Enhance the Mechanical Strength and the Cyclability of Si-Based Electrodes for Li-Ion Batteries, Adv. Energy Mater, 2017, 1701787. [4] V. Vanpenne et al., Adv. Energy Mater, Dynamics of the morphological degradation of Si-based anodes for Li-ion batteries characterized by in-situ synchrotron X-ray tomography, Adv. Energy Mater. 9, 2019, 1803947 [5] D. Mazouzi et al., CMC-citric acid Cu(II) cross-linked binder approach to improve the electrochemical performance of Si-based electrodes Electrochimica Acta, 2019, 304, 495-504. [6] T. Devic, B. Lestriez, L. Roué, Silicon Electrodes for Li-Ion Batteries. Addressing the Challenges through Coordination Chemistry, ACS Energy Letters, ACS Energy Lett., 2019, 4, 550−557.
Accurate TDDB Lifetime Prediction of High-k Stacked Gate Dielectrics <br> with Regarding High Density Initial Traps (2007)

Essentials required for the accurate TDDB lifetime (T BD ) prediction of high-k stacked gate dielectrics are discussed. For this purpose, thorough understanding of the time dependent dielectric breakdown (TDDB) mechanism is indispensable, along with clarifying its stress gate voltage (V G ) dependence. As for the TDDB mechanism, we propose the Generated Subordinate Carrier Injection (GSCI) model, which presumes that the degradation is dominated by the injected subordinate carriers (I DC ). Because of the coexistence of the current component which does not contribute to the breakdown such as the trap-assisted current, the decomposition of the subordinate carrier current to each component is needed. On the other hand, to obtain the stress V G dependence of T BD , we point out the universal relationship between the voltage acceleration factor of T BD and the stress V G . It is demonstrated that the accurate lifetime prediction can be realized on the basis of the GSCI model combined with this universality.
Hybrid integration methods for on-chip quantum photonics (2020)

The goal of integrated quantum photonics is to combine components for the generation, manipulation, and detection of nonclassical light in a phase-stable and efficient platform. Solid-state quantum emitters have recently reached outstanding performance as single-photon sources. In parallel, photonic integrated circuits have been advanced to the point that thousands of components can be controlled on a chip with high efficiency and phase stability. Consequently, researchers are now beginning to combine these leading quantum emitters and photonic integrated circuit platforms to realize the best properties of each technology. In this paper, we review recent advances in integrated quantum photonics based on such hybrid systems. Although hybrid integration solves many limitations of individual platforms, it also introduces new challenges that arise from interfacing different materials. We review various issues in solid-state quantum emitters and photonic integrated circuits, the hybrid integration techniques that bridge these two systems, and methods for chip-based manipulation of photons and emitters. Finally, we discuss the remaining challenges and future prospects of on-chip quantum photonics with integrated quantum emitters.
The Integrin Binding Peptide, ATN-161, as a Novel Therapy for SARS-CoV-2 Infection (2020)

Many efforts to design and screen therapeutics for the current severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) pandemic have focused on inhibiting viral host cell entry by disrupting angiotensin-converting enzyme-2 (ACE2) binding with the SARS-CoV-2 spike protein. This work focuses on the potential to inhibit SARS-CoV-2 entry through a hypothesized α5β1 integrin-based mechanism and indicates that inhibiting the spike protein interaction with α5β1 integrin (+/- ACE2) and the interaction between α5β1 integrin and ACE2 using a novel molecule (ATN-161) represents a promising approach to treat coronavirus disease-19.
Observation of sub-Poisson Photon Statistics in the Cavity-QED Microlaser (2006)

We have measured the second-order correlation function of the cavity-QED microlaser output and observed a transition from photon bunching to antibunching with increasing average number of intracavity atoms. The observed correlation times and the transition from super- to sub-Poisson photon statistics can be well described by gain-loss feedback or enhanced-reduced restoring action against fluctuations in photon number in the context of a quantum microlaser theory and a photon rate equation picture. However, the theory predicts a degree of antibunching several times larger than that observed, which may indicate the inadequacy of its treatment of atomic velocity distributions.
Characterization and Transferability of Class 1 Integrons in Commensal Bacteria Isolated from Farm and Nonfarm Environments (2010)

This study assessed the distribution of class 1 integrons in commensal bacteria isolated from agricultural and nonfarm environments, and the transferability of class 1 integrons to pathogenic bacteria. A total of 26 class 1 integron-positive isolates were detected in fecal samples from cattle operations and a city park, water samples from a beef ranch and city lakes, and soil, feed (unused), manure, and compost samples from a dairy farm. Antimicrobial susceptibility testing of class 1 integron-positive Enterobacteriaceae isolates from city locations displayed multi-resistance to 12-13 out of the 22 antibiotics tested, whereas class 1 integron-positive Enterobacteriaceae isolates from cattle operations only displayed tetracycline resistance. Most class 1 integrons had one gene cassette belonging to the aadA family that confers resistance to streptomycin and spectinomycin. One isolate from a dog fecal sample collected from a city dog park transferred its class 1 integron to a strain of Escherichia coli O157:H7 at a frequency of 10(-7) transconjugants/donor by in vitro filter mating experiments under the stated laboratory conditions. Due to the numerous factors that may affect the transferability testing, further investigation using different methodologies may be helpful to reveal the transferability of the integrons from other isolates. The presence of class 1 integrons among diverse commensal bacteria from agricultural and nonfarm environments strengthens the possible role of environmental commensals in serving as reservoirs of antibiotic resistance genes.
Provably good routing in graphs: regular arrays (1985)

We examine the problem of routing wires on a VLSI chip where the nodes to be connected are arranged in a two-dimensional array. We develop provably good algorithms that find a solution close to the optimal one with high probability. Our approximation algorithms solve the relevant 0-1 integer optimization problems by solving their relaxed versions and then rounding by an interesting probabilistic technique. One of our algorithms, using multicommodity flow, has applications to routing in circuit switching networks.
Non-covalent expansion of an organic bilayer involving exo-cavity interplay of tetraphenylphosphonium with para-sulfonato-calix[4]arene (2005)

Reaction of equimolar amounts of sodium para-sulfonato-calix[4]arene, tetraphenylphosphonium chloride and ytterbium chloride in water results in the formation of a mineral clay-like structure, where the hydrophobic tetraphenylphosphonium cations interpose a bilayer arrangement based on a 2D coordination polymer of (calix[4]arene)5-/Na+/Yb3+.
Photolithography (1999)

Abstract The sections in this article are Overview of Optical Lithography Patterning Issues Optical Lithography Extensions Successors to Optical Lithography Conclusion Acknowledgments
WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death (2017)

The WNT pathway mediates intercellular signaling that regulates cell fate in both normal development and cancer. It is widely appreciated that the WNT pathway is frequently dysregulated in human cancers through a variety of genetic and epigenetic mechanisms. Targets in the WNT pathway are being extensively pursued for the development of new anticancer therapies, and we have advanced two WNT antagonists for clinical development: vantictumab (anti-FZD) and ipafricept (FZD8-Fc). We examined the antitumor efficacy of these WNT antagonists in combination with various chemotherapies in a large set of patient-derived xenograft models. In responsive models, WNT blockade led to profound synergy with taxanes such as paclitaxel, and the combination activity with taxanes was consistently more effective than with other classes of chemotherapy. Taxane monotherapy increased the frequency of cells with active WNT signaling. This selection of WNT-active chemotherapy-resistant tumorigenic cells was prevented by WNT-antagonizing biologics and required sequential dosing of the WNT antagonist followed by the taxane. The WNT antagonists potentiated paclitaxel-mediated mitotic blockade and promoted widespread mitotic cell death. By blocking WNT/β-catenin signaling before mitotic blockade by paclitaxel, we found that this treatment effectively sensitizes cancer stem cells to taxanes. This combination strategy and treatment regimen has been incorporated into ongoing clinical testing for vantictumab and ipafricept.
Creating an Ambient-Intelligence Environment Using Embedded Agents (2004)

The Essex intelligent dormitory, iDorm, uses embedded agents to create an ambient-intelligence environment. In a five-and-a-half-day experiment, a user occupied the iDorm, testing its ability to learn user behavior and adapt to user needs. The embedded agent discreetly controls the iDorm according to user preferences. Our work focuses on developing learning and adaptation techniques for embedded agents. We seek to provide online, lifelong, personalized learning of anticipatory adaptive control to realize the ambient-intelligence vision in ubiquitous-computing environments. We developed the Essex intelligent dormitory, or iDorm, as a test bed for this work and an exemplar of this approach.
Ultra-low power silicon photonic transceivers for inter/intra-chip interconnects (2010)

Scaling of high performance, many-core, computing systems calls for disruptive solutions to provide ultra energy efficient and high bandwidth density interconnects at very low cost. Silicon photonics is viewed as a promising solution. For silicon photonics to prevail and penetrate deeper into the computing system interconnection hierarchy, it requires innovative optical devices, novel circuits, and advanced integration. We review our recent progress in key building blocks toward sub pJ/bit optical link for inter/intra-chip applications, ultra-low power silicon photonic transceivers. In particular, compact reverse biased silicon ring modulator was developed with high modulation bandwidth sufficient for 15Gbps modulation, very small junction capacitance of ~50fF, low voltage swing of 2V, high extinction ratio (&gt;7dB) and low optical loss (~2dB at on-state). Integrated with low power CMOS driver circuits using low parasitic microsolder bump technique, we achieved record low power consumption of 320fJ/bit at 5Gbps data rate. Stable operation with biterror- rate better than 10<sup>-13 </sup>was accomplished with simple thermal management. We further review the first hybrid integrated silicon photonic receiver based on Ge waveguide photo detector using the same integration technique, with which high energy efficiency of 690fJ/bit, and sensitivity of ~18.9dBm at 5Gbps data rate for bit-error-rate of 10<sup>-12 </sup>were achieved.
Multi-gateway cooperation in multibeam satellite systems (2012)

Multibeam systems with hundreds of beams have been recently deployed in order to provide higher capacities by employing fractional frequency reuse. Furthermore, employing full frequency reuse and precoding over multiple beams has shown great throughput potential in literature. However, feeding all this data from a single gateway is not feasible based on the current frequency allocations. In this context, we investigate a range of scenarios involving beam clusters where each cluster is managed by a single gateway. More specifically, the following cases are considered for handling intercluster interference: a) conventional frequency colouring, b) joint processing within cluster, c) partial CSI sharing among clusters, d) partial CSI and data sharing among clusters. CSI sharing does not provide considerable performance gains with respect to b) but combined with data sharing offers roughly a 40% improvement over a) and a 15% over b).
Digital Phase Lock Loops: Architectures and Applications (2006)

Digital phase lock loops are critical components of many communication, signal processing and control systems. This exciting new book covers various types of digital phase lock loops. It presents a comprehensive coverage of a new class of digital phase lock loops called the time delay tanlock loop (TDTL). It also details a number of architectures that improve the performance of the TDTL through adaptive techniques that overcome the conflicting requirements of the locking rage and speed of acquisition. These requirements are of paramount importance in many applications including wireless communications, consumer electronics and others. Digital Phase Lock Loops then illustrates the process of converting the TDTL class of digital phase lock loops for implementation on an FPGA-based reconfigurable system. These devices are being utilized in software-defined radio, DSP-based designs and many other communication and electronic systems to implement complex high-speed algorithms. Their flexibility and reconfigurability facilitate rapid prototyping, on-the-fly upgradeability, and code reuse with minimum effort and complexity. The practical real-time results, of the various TDTL architectures, obtained from the reconfigurable implementations are compared with those obtained through simulations with MATLAB/Simulink. The material in this book will be valuable to researchers, graduate students, and practicing engineers.
Abstract 3211: MTL-CEBPA combined with radiofrequency ablation and immunotherapy enhances immunological anti-tumour response in an HCC mouse model (2019)

Abstract The transcription factor CEBPA (CCAAT/enhancer-binding protein alpha) is recognised for its antiproliferative effects. MTL-CEBPA is a small activating RNA drug which upregulates gene expression of CEBPA and amongst other effects causes and immunomodulatory effect on peripheral granulocytes. Radiofrequency ablation (RFA) is standard treatment for some tumour types such as liver cancer and induces modulation of both innate and adaptive immune systems. To investigate any synergistic effect of MTL-CEBPA with RFA and immune checkpoint inhibition we initiated a reverse translation experiment, where syngeneic BNL hepatocellular carcinoma tumour cells were injected in the two opposite flanks of immunocompetent BALB/c mice (n=8 in each group). Treatments for hepatoma bearing mice included: 1) RFA on one flank (day 0), 2) Anti-PD-1 inhibition immunotherapy (RMP1-14 antibody, BioXCell, West Lebanon, NH, USA at 200 μg IV/mouse/dose on days 0, 2 &amp; 5) and 3) MTL-CEBPA (3mg/kg IV/mouse/dose on days 0, 2 &amp; 5) as well as combinations of all 3 interventions. We found that tumour control on the opposite flank was augmented by addition of RFA and most significant in the triple combination group (RFA + anti-PD1 + MTL-CEBPA) in which 2/8 animals showed a complete response and 5/8 a partial response. This was also the only group that showed a statistically significant increase in CD8+ (Cytotoxic) as well as CD49b+/CD45+ (Natural Killer) tumour infiltrating lymphocytes. These data suggest a clinical role for combination treatment with checkpoint blockade, RFA and MTL-CEBPA through synergistic priming of the immune tumour response, enabling RFA to have a pronounced anti-tumour abscopal effect. Citation Format: Mikael H. Sodergren, Kai-Wen Huang, Vikash Reebye, Cheng-Ean Chee, Dimitris Zacharoulis, Robert Habib, David Blakey, John Rossi, Nagy Habib. MTL-CEBPA combined with radiofrequency ablation and immunotherapy enhances immunological anti-tumour response in an HCC mouse model [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2019; 2019 Mar 29-Apr 3; Atlanta, GA. Philadelphia (PA): AACR; Cancer Res 2019;79(13 Suppl):Abstract nr 3211.
Smart manufacturing of low-cost integrated panel by resin transfer molding (2003)

Smart manufacturing process was developed to manufacture the demonstrator access door panel. The process integrated three basic methods, process simulation, process monitoring, and process control. For the first step, we simulated and predicted how the resin impregnated through the perform. And taking this result into consideration, we fixed the process parameters. In manufacturing, the dielectric film sensor was placed on the surface of the mold cavity to evaluate the resin flow. Dielectric property of the sensor changed as the resin impregnated. Dielectric sensor system is linked to the process control system. A personal computer of the control system acquired the process data from sensor system and controlled the pressure of the injection point. The three-dimensional door panel, 700mm width, with Fiber Bragg Grating (FBG) sensors embedded, without any dry-spot existing, was manufactured by this method. Effectiveness and advancement of smart manufacturing process was confirmed.