gebhart/patrepeval huggingface dataset:
Correction to “Highly Efficient Photo- and Electroluminescence from Two-Coordinate Cu(I) Complexes Featuring Nonconventional N-Heterocyclic Carbenes” (2019)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to "Highly Efficient Photo- and Electroluminescence from Two-Coordinate Cu(I) Complexes Featuring Nonconventional N-Heterocyclic Carbenes"Shuyang ShiShuyang ShiMore by Shuyang Shihttp://orcid.org/0000-0002-4067-2982, Moon Chul JungMoon Chul JungMore by Moon Chul Junghttp://orcid.org/0000-0001-7571-3767, Caleb CoburnCaleb CoburnMore by Caleb Coburn, Abegail TadleAbegail TadleMore by Abegail Tadlehttp://orcid.org/0000-0002-3802-6818, M. R. Daniel SylvinsonM. R. Daniel SylvinsonMore by M. R. Daniel Sylvinson, Peter I. DjurovichPeter I. DjurovichMore by Peter I. Djurovichhttp://orcid.org/0000-0001-6716-389X, Stephen R. ForrestStephen R. ForrestMore by Stephen R. Forresthttp://orcid.org/0000-0003-0131-1903, and Mark E. Thompson*Mark E. ThompsonMore by Mark E. Thompsonhttp://orcid.org/0000-0002-7764-4096Cite this: J. Am. Chem. Soc. 2019, 141, 45, 18356Publication Date (Web):November 5, 2019Publication History Published online5 November 2019Published inissue 13 November 2019https://pubs.acs.org/doi/10.1021/jacs.9b11526https://doi.org/10.1021/jacs.9b11526correctionACS PublicationsCopyright © 2019 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views3485Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (295 KB) Get e-Alertsclose Get e-Alerts
AlGaAs soliton microcombs at room temperature (2023)

Soliton generation in AlGaAs microresonators at room temperation is reported for the first time. The destabilizing thermo-optic effect is shown to instead provide stability for high soliton repetition rates. The optical pump power is sub-milliWatt.
ChemInform Abstract: Hepatitis C Viral IRES Inhibition by Phenazine and Phenazine‐Like Molecules. (2000)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Ezh2 represses the basal cell lineage during lung endoderm development (2014)

The development of the lung epithelium is regulated in a stepwise fashion to generate numerous differentiated and stem cell lineages in the adult lung. How these different lineages are generated in a spatially and temporally restricted fashion remains poorly understood, although epigenetic regulation probably plays an important role. We show that the Polycomb repressive complex 2 component Ezh2 is highly expressed in early lung development but is gradually downregulated by late gestation. Deletion of Ezh2 in early lung endoderm progenitors leads to the ectopic and premature appearance of Trp63+ basal cells that extend the entire length of the airway. Loss of Ezh2 also leads to reduced secretory cell differentiation. In their place, morphologically similar cells develop that express a subset of basal cell genes, including keratin 5, but no longer express high levels of either Trp63 or of standard secretory cell markers. This suggests that Ezh2 regulates the phenotypic switch between basal cells and secretory cells. Together, these findings show that Ezh2 restricts the basal cell lineage during normal lung endoderm development to allow the proper patterning of epithelial lineages during lung formation.
Molecular Breast Imaging in Clinical Practice (2020)

<b>OBJECTIVE.</b> The purpose of this article is to review clinical uses and image interpretation of molecular breast imaging (MBI) and clarify radiation risks. <b>CONCLUSION.</b> MBI detects additional cancers compared with conventional imaging in women with dense breasts and those with elevated risk of breast cancer. Its role as an imaging biomarker of cancer risk and in assessing neoadjuvant chemotherapy response is growing. Radiation risk is minimal; benefit-to-risk ratio is similar to that of mammography. MBI is low cost, well tolerated, and easily adapted into clinical practice.
Risk Factors for Orthostatic Hypotension: Differences Between Elderly Men and Women (2018)

Background Orthostatic hypotension (OH) occurs when mechanisms regulating blood pressure (BP) levels after standing-up are altered. It is unclear how prevalence and risk factors for OH are different between sexes. We aimed to investigate sex differences in prevalence and risk factors for OH elderly individuals. Methods We included 882 participants from Maracaibo Aging Study. OH was a sustained reduction of ≥20 mm Hg in systolic BP, ≥10 mm Hg in diastolic BP, or both, after 3 minutes of changing positions from supine to standing. Multivariable logistic regression models were used to examine the relationships among risk factors for OH in men and women considering interaction sex-term and stratified by sex. Results The mean age was 66.7 ± 8.5 years, being similar by sex. Women and men 55-74 years had similar prevalence of OH+ (18.5% vs. 20.9%, respectively). After 75 years, the proportion of women with OH+ was lower than men (11% vs. 30%, respectively). Hypertension, specifically systolic BP ≥140 mm Hg, and high pulse pressure (PP) were related with OH+ accounted by interaction sex-term, while diastolic BP ≥90 mm Hg, antihypertensive treatment, body mass index (BMI), diabetes mellitus and age were not. Systolic BP ≥140 mm Hg increases the risk of OH only among women, while BMI showed an inverse association in both sexes. Conclusions Although the prevalence of OH is similar in both sexes, there are different risk factors associated by sex. Systolic BP ≥140 mm Hg was associated with increased risk of OH only with women while BMI was a protective factor for OH in men and women.
Epoxidized soybean oil modified using fatty acids as tougheners for thermosetting epoxy resins: Part 1 (2021)

Abstract A series of bio‐rubber (BR) reactive tougheners for thermosetting epoxy resins was prepared by grafting renewable saturated fatty acids of different chain lengths (C6‐C14) onto epoxidized soybean oil (ESO) at varying molar ratios. The tunable nature of the BR systems derives from the architecture and functionality of naturally occurring molecules. Control of BR reactivity and molecular weight by varying the degree of grafting and the chain length of the fatty acid was demonstrated. The BR‐toughened samples were prepared by blending BRs with diglycidyl ether of bisphenol A (DGEBA), Epon 828, and stoichiometrically curing the mixture using an aromatic amine hardener, diethyl toluene diamine (Epikure W). Fracture surface morphology studies showed that tuning of phase separated particle sizes was possible depending on the BR type and weight fraction. The resulting toughening effect was evaluated by measuring the fracture toughness of control and toughened polymer samples. The use of BRs significantly improved the critical strain energy release rate and critical stress intensity factor values of thermosetting polymer samples without significantly reducing T g and modulus. In addition to toughening and adding renewable content to petroleum‐based thermosetting epoxy systems these new tougheners have low viscosity compared to common alternatives and aid ease of processing.
CoAP-XED: Enabling Relaxed Requests to IoT Sensing Resources (2018)

In the context of the Internet of Things (IoT), a new service model has emerged, namely, the Sensing as a Service (S <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> aaS). In such model, sensing data is available for external users as resources, and can be provided on demand, as services. Typically, the devices providing sensing resources are powered by batteries, thus the lifetime of devices becomes a concern to IoT service providers. A common strategy to reduce the number of tasks to be performed by the devices, thus saving energy, is caching data, reusing a prior response message to satisfy a current request. However, on the side of IoT service consumers, the freshness of the data is also a critical concern. That is, the time elapsed since the data is collected until it is delivered to the requesting user should be small. In high workload scenarios, addressing both lifetime and data freshness requirements may be challenging, mainly because commonly used application protocols, such as the Constrained Application Protocol (CoAP), only allow specifying the data freshness requirement in a strict way. This paper introduces an extension to CoAP, namely, CoAP-XED, aiming at supporting the relaxation of requests to sensing resources. Simulation results show that our approach supports maximizing the lifetime of devices and, at the same time, fulfill data freshness requirements.
451 Analysis and Evaluation of the Ride Comfort on Standing Posture (2003)

This paper presents an evaluation method of the ride comfort associated with dynamic characteristics of the human body targeting commuter trains. First, measurements of the frequency responses of the head, shoulder, waist and knee under the sine wave or train floor vibration has been performed. Secondly, multi regression analysis has been carried out for the evaluation of the ride comfort. As a result, some features of dynamic characteristics on standing posture and the correlation of the ride comfort with dynamic characteristics have been found. The evaluation equation has been proposed.
Slow Binding Inhibition of Phospho-N-acetylmuramyl-pentapeptide-translocase (Escherichia coli) by Mureidomycin A (1996)

Enzymes of the membrane cycle of reactions in bacterial peptidoglycan biosynthesis remain as unexploited potential targets for antibacterial agents. The first of these enzymes, phospho-N-acetylmuramyl-pentapeptide-translocase (EC 2.7.8.13), has been overexpresed in Escherichia coli and solubilized from particulate fractions. The work of W.A. Weppner and F.C. Neuhaus ((1977) J. Biol. Chem. 252, 2296-303) has been extended to establish a usable routine fluorescence-based continuous assay for solubilized preparations. This assay has been used in the characterization of the natural product, mureidomycin A as a potent slow binding inhibitor of the enzyme with Ki and Ki* of 36 nM and 2 nM, respectively.
Mode-crossing spectroscopy for photonic waveguide characterization (2019)

We report a novel spectroscopic technique to characterize photonic waveguides over more than an octave of wavelength. The technique, called mode-crossing spectroscopy, uses a broadband source and a spectrometer that are coupled to the input and output ends of a series of straight dielectric waveguides via single-mode optical fibers. Measurements of the wavelengths at which multiple modes are degenerate in a single waveguide enable the determination of the refractive index of the core, as well as the waveguide width variation. In addition, mode-dependent losses are reported from 700 nm to 1550 nm using waveguides of varying lengths. The core refractive indices are measured within an error of ±0.5%, waveguide width variation to an accuracy of less than 5 nm, and waveguide propagation losses within an error of ±0.5 dB/cm. Ultrabroadband in situ measurements of loss and index over an octave of bandwidth are crucial for the accurate characterization of photonic integrated circuits and devices, especially those based on precision broadband couplers, interferometers, and resonant cavities.
Transformation process for production of ultrahigh carbon steels and new alloys (2023)

Ultrahigh carbon steels with superplastic properties are produced by heating a steel containing ferrite and carbide phases to a soaking temperature approximately 50.degree. C. above the A.sub.1 transformation temperature, soaking the steel above the A.sub.1 temperature for a sufficient time that the major portion of the carbides dissolve into the austenite matrix, and then cooling the steel in a controlled manner within predetermined limits of cooling rate or transformation temperature, to obtain a steel having substantially spheroidal carbides. New alloy compositions contain aluminum and solute additions which promote the formation of a fine grain size and improve the resistance of the carbides to coarsening at the forming temperature.
Optical design and imaging performance testing of a 96-mm diameter femtosecond laser microsurgery probe (2011)

We present the optical design of a 9.6-mm diameter fiber-coupled probe for combined femtosecond laser microsurgery and nonlinear optical imaging. Towards enabling clinical use, we successfully reduced the dimensions of our earlier 18-mm microsurgery probe by half, while improving optical performance. We use analytical and computational models to optimize the miniaturized lens system for off-axis scanning aberrations. The optimization reveals that the optical system can be aberration-corrected using simple aspheric relay lenses to achieve diffraction-limited imaging resolution over a large field of view. Before moving forward with custom lenses, we have constructed the 9.6-mm probe using off-the-shelf spherical relay lenses and a 0.55 NA aspheric objective lens. In addition to reducing the diameter by nearly 50% and the total volume by 5 times, we also demonstrate improved lateral and axial resolutions of 1.27 µm and 13.5 µm, respectively, compared to 1.64 µm and 16.4 µm in our previous work. Using this probe, we can successfully image various tissue samples, such as rat tail tendon that required 2-3 × lower laser power than the current state-of-the-art. With further development, image-guided, femtosecond laser microsurgical probes such as this one can enable physicians to achieve the highest level of surgical precision anywhere inside the body.
Practical Strategies for Integrating a Conversation Analyst in an Iterative Design Process (2002)

We present a case study of an iterative design process that includes a conversation analyst. We discuss potential benefits of conversation analysis for design, and we describe our strategies for integrating the conversation analyst in the design process. Since the analyst on our team had no previous exposure to design or engineering, and none of the other members of our team had any experience with conversation analysis, we needed to build a foundation for our interaction. One of our key strategies was to pair the conversation analyst with a designer in a highly interactive collaboration. Our tactics have been effective on our project, leading to valuable results that we believe we could not have obtained using another method. We hope that this paper can serve as a practical guide to those interested in establishing a productive and efficient working relationship between a conversation analyst and the other members of a design team.
Anomalous perovskite PbRuO 3 stabilized under high pressure (2013)

Perovskite oxides ABO3 are important materials used as components in electronic devices. The highly compact crystal structure consists of a framework of corner-shared BO6 octahedra enclosing the A-site cations. Because of these structural features, forming a strong bond between A and B cations is highly unlikely and has not been reported in the literature. Here we report a pressure-induced first-order transition in PbRuO3 from a common orthorhombic phase (Pbnm) to an orthorhombic phase (Pbn21) at 32 GPa by using synchrotron X-ray diffraction. This transition has been further verified with resistivity measurements and Raman spectra under high pressure. In contrast to most well-studied perovskites under high pressure, the Pbn21 phase of PbRuO3 stabilized at high pressure is a polar perovskite. More interestingly, the Pbn21 phase has the most distorted octahedra and a shortest Pb-Ru bond length relative to the average Pb-Ru bond length that has ever been reported in a perovskite structure. We have also simulated the behavior of the PbRuO3 perovskite under high pressure by first principles calculations. The calculated critical pressure for the phase transition and evolution of lattice parameters under pressure match the experimental results quantitatively. Our calculations also reveal that the hybridization between a Ru:t2g orbital and an sp hybrid on Pb increases dramatically in the Pbnm phase under pressure. This pressure-induced change destabilizes the Pbnm phase to give a phase transition to the Pbn21 phase where electrons in the overlapping orbitals form bonding and antibonding states along the shortest Ru-Pb direction at P > Pc.
Identification and ranking of subaerial volcanic tsunami hazard sources in Southeast Asia (2022)

Abstract. Tsunamis caused by large volcanic eruptions and flanks collapsing into the sea are major hazards for nearby coastal regions. They often occur with little precursory activity and are thus challenging to detect in a timely manner. This makes the pre-emptive identification of volcanoes prone to causing tsunamis particularly important, as it allows for better hazard assessment and denser monitoring in these areas. Here, we present a catalogue of potentially tsunamigenic volcanoes in Southeast Asia and rank these volcanoes by their tsunami hazard. The ranking is based on a multicriteria decision analysis (MCDA) composed of five individually weighted factors impacting flank stability and tsunami hazard. The data are sourced from geological databases, remote sensing data, historical volcano-induced tsunami records, and our topographic analyses, mainly considering the eruptive and tsunami history, elevation relative to the distance from the sea, flank steepness, hydrothermal alteration, and vegetation coverage. Out of 131 analysed volcanoes, we found 19 with particularly high tsunamigenic hazard potential in Indonesia (Anak Krakatau, Batu Tara, Iliwerung, Gamalama, Sangeang Api, Karangetang, Sirung, Wetar, Nila, Ruang, Serua) and Papua New Guinea (Kadovar, Ritter Island, Rabaul, Manam, Langila, Ulawun, Bam) but also in the Philippines (Didicas). While some of these volcanoes, such as Anak Krakatau, are well known for their deadly tsunamis, many others on this list are lesser known and monitored. We further performed tsunami travel time modelling on these high-hazard volcanoes, which indicates that future events could affect large coastal areas in a short time. This highlights the importance of individual tsunami hazard assessment for these volcanoes, the importance of dedicated volcanological monitoring, and the need for increased preparedness on the potentially affected coasts.
ChemInform Abstract: Synthesis and Antiviral Evaluation of the β‐L‐Enantiomers of Some Thymine 3′‐Deoxypentofuranonucleoside Derivatives. (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Dual-Isotope SPECT/CT Imaging of the Tuberculosis Subunit Vaccine H56/CAF01: Induction of Strong Systemic and Mucosal IgA and T-Cell Responses in Mice Upon Subcutaneous Prime and Intrapulmonary Boost Immunization (2018)

Pulmonary tuberculosis (TB), which is caused by <i>Mycobacterium tuberculosis</i> (<i>Mtb)</i>, remains a global pandemic, despite the widespread use of the parenteral live attenuated Bacillus Calmette-Guérin (BCG) vaccine during the past decades. Mucosal administration of next generation TB vaccines has great potential, but developing a safe and efficacious mucosal vaccine is challenging. Hence, understanding the <i>in vivo</i> biodistribution and pharmacokinetics of mucosal vaccines is essential for shaping the desired immune response and for optimal spatiotemporal targeting of the appropriate effector cells in the lungs. A subunit vaccine consisting of the fusion antigen H56 (Ag85B-ESAT-6-Rv2660) and the liposome-based cationic adjuvant formulation (CAF01) confers efficient protection in preclinical animal models. In this study, we devise a novel immunization strategy for the H56/CAF01 vaccine, which comply with the intrapulmonary (i.pulmon.) route of immunization. We also describe a novel dual-isotope (<sup>111</sup>In/<sup>67</sup>Ga) radiolabeling approach, which enables simultaneous non-invasive and longitudinal SPECT/CT imaging and quantification of H56 and CAF01 upon parenteral prime and/or i.pulmon. boost immunization. Our results demonstrate that the vaccine is distributed evenly in the lungs, and there are pronounced differences in the pharmacokinetics of H56 and CAF01. We provide convincing evidence that the H56/CAF01 vaccine is not only well-tolerated when administered to the respiratory tract, but it also induces strong lung mucosal and systemic IgA and polyfunctional Th1 and Th17 responses after parenteral prime and i.pulmon. boost immunization. The study furthermore evaluate the application of SPECT/CT imaging for the investigation of vaccine biodistribution after parenteral and i.pulmon. immunization of mice.
RELATIVISTIC MAGNETRONS’ DEVELOPMENT STAGES (2016)

В статье отражены основные этапы развития релятивистских магнетронов.Описаны конструкции, устраняющие ряд недостатков, присущих традиционным магнетронам с радиальным выводом излучения через узкую щель из одного резонатора.К таким ограничениям относятся: работа только на невырожденных колебаниях, кратных π-моде, и низкий порог высокочастотного пробоя.Конструкция магнетрона, рассматриваемая в данной статье, имеет дифракционный вывод излучения, все резонаторы анодного блока продолжены в коническую антенну до сечения, превышающего сечение, соответствующее частоте отсечки излучаемой волны.Такой магнетрон с аксиальным симметричным выводом излучения может работать на любой моде, и перескок на вырожденный вид колебаний не приводит к катастрофе, как это иногда случается в традиционных магнетронах.Для резонаторов, продолженных с увеличивающейся глубиной в антенну, оптимизированный вывод позволил значительно увеличить эффективность релятивистского магнетрона.Так, в первом же эксперименте достигнут электронный КПД более 60%