gebhart/patrepeval huggingface dataset:
Patch warping based face frontalization (2018)

Face frontalization increases accuracies of face and gesture recognition applications. In this paper, we propose a 2D patch warping based face frontalization method which that has a simple but efficient flow due to its lower computation cost. We partition the human face into 23 nearly planar regions that are constituted by 68 landmark points to form a frontal face model and used for warping process. Planar places warped by using homography unlike other affine transform based methods. Warping rectangle regions with homography preserve global structure of face as well as it decreased the computational cost of frontalization as againts situations that work with a lot of triangular region like Delaunay triangulation. In order to test recognition performance, every test sample frontalized with respect to average face model computed as the average of all train samples. Test sets created by the pose angles of samples, tested separately to measure the contribution of proposed method to recognition and we compare the proposed method to another state of art frontalization method in literature.
Tuft Cell Regulation of miRNAs in Pancreatic Cancer (2013)

Abstract : To better understand the role of tuft cells in the pancreas and to define their effects on the pancreatic body as well as the initiation of pancreatic cancer. Tuft cells are present in the hollow organs of the digestive and respiratory tracts. They are characterized by long and blunt microvilli with prominent rootlets and by a well-developed tubulovesicular system in the supranuclear cytoplasm. Recent reports suggest that tuft cells may act as mechanoreceptors and are involved in chemosensensing of the microenvironment. With the successful deletion of Dclk1 throughout the pancreatic ducts, we have characterized, which extends our understanding of the role tuft cells play within ducts and their broader effects on the overall pancreatic microenvironment. We observed that Dclk1 co-localized with other putative tuft cell markers including Cox1 and Cox2. Additionally, we also observed the presence of the tuft cells of wild type and Pdx-1-Cre;Dclk1floxlflox mice, indicating that Dclk1 may not play a role in tuft cells at baseline. We performed additional experiments to demonstrate the role of Dclk1 in pancreatic inflammation leading to pancreatic neoplasia. Dclk1 played a vital role in governing and is essential for pancreatic inflammatory process and associated metaplastic progression following caerulein-induced acinar ductal metaplasia. These finding could very well provide the basis for the development of novel chemotherapeutic drugs targeting these specialized cells expressing Dclk1 for eradication of pancreatitis and pancreatic adenocarcinoma.
Low Cost Hybrid Spin-CMOS Compressor for Stochastic Neural Networks (2019)

With expansion of neural network (NN) applications lowering their hardware implementation cost becomes an urgent task especially in back-end applications where the power-supply is limited. Stochastic computing (SC) is a promising solution to realize low-cost hardware designs. Implementation of matrix multiplication has been a bottleneck in previous stochastic neural networks (SC-NNs). In this paper, we introduce spintronic components into the design of SC-NNs. A novel spin-CMOS matrix multiplier is proposed in which the stochastic multiplications are performed by CMOS AND gates while the sum of products is implemented by spintronic compressor gates. The experimental results indicate that compared to the conventional binary implementations the proposed hybrid spin-CMOS architecture can achieve over 125x, 4.5x and 43x; reduction in terms of power, energy and area consumptions, respectively. Moreover, compared to previous CMOS-based SC-NNs, our design saves the power by 3.1x - 7.3x, reduces energy consumption by 3.1x - 7.3x and decreases area by 1.4x - 7.6x while maintaining similar recognition rates.
Réarrangements en milieu acide trifluoroacétique de deux alcaloïdes indoliques: la desformocorymine et la dihydrocorymine (1983)

The rearrangement in trifluoroacetic acid of two indole alkaloids of the echitamine series, desformocorymine (14) and dihydrocorymine (9) , has been investigated. Desformocorymine (14) was tranformed into a mixture of carbinolamines 17a , b , with the akuammiline skeleton, which were reduced (Et 3 SiH, CF 3 CO 2 H) into an isomer 12 of cathafoline (6). This sequence constitutes the first example of an interconversion of the corymine skeleton into the akuammiline skeleton (Scheme 2) . In the case of dihydrocorymine (9) , the rearrangement followed a different pathway owing to the formation of a hemiacetal between the primary alcohol CH 2 (17)‐OH and a carbonyl formed at C(3). Treatment of this hemiacetal 26 with aqueous base led to its opening with concomitant formation of a lactam. 13 C‐NMR seems to indicate that this lactam exists under a hydrated form 27. This highly unstable intermediate was cleanly transformed (MeONa‐MeOH) into a 2‐acyl indole 30 (Scheme 4) , the structure of which was determined by X‐ray crystallography. The formation of this acylindole involves the rupture of the C(7)C(16) bond; it is the reverse of the reaction generally postulated as occurring in the biogenesis of the pentacyclic alkaloids. The structure of a by‐product 34 was established as 17‐hydroxymethylvincoridine by X‐ray crystallography. The acid‐catalyzed rearrangements involve the rupture of the Ph‐NCN chromophore, with formation of a carbonyl at C(3). The reversibility of these steps is used in an easy correlation of dihydrocorymine and of 3‐epidihydrocorymine via their trifluoroacetates.
Synthetic studies on tetrodotoxin and related compounds. III. Stereospecific synthesis of an equivalent of acetylated tetrodamine (1972)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthetic studies on tetrodotoxin and related compounds. III. Stereospecific synthesis of an equivalent of acetylated tetrodamineY. Kishi, M. Aratani, T. Fukuyama, F. Nakatsubo, T. Goto, S. Inoue, H. Tanino, S. Sugiura, and H. KakoiCite this: J. Am. Chem. Soc. 1972, 94, 26, 9217–9219Publication Date (Print):December 1, 1972Publication History Published online1 May 2002Published inissue 1 December 1972https://pubs.acs.org/doi/10.1021/ja00781a038https://doi.org/10.1021/ja00781a038research-articleACS PublicationsRequest reuse permissionsArticle Views3355Altmetric-Citations117LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Measurement of $${\Upsilon } $$ Υ production in $${{\mathrm {p}}} {{\mathrm {p}}} $$ p p collisions at $${\sqrt{s}} =2.76{\mathrm {\,TeV}} $$ s = 2.76 TeV (2014)

The production of (1S), (2S) and (3S) mesons decaying into the dimuon final state is studied with the LHCb detector using a data sample corresponding to an integrated luminosity of 3.3 pb -1 collected in proton-proton collisions at a centre-of-mass energy of s = 2.76 TeV. The differential production cross-sections times dimuon branching fractions are measured as functions of the transverse momentum and rapidity, over the ranges p T < 15 GeV/c and 2.0 < y < 4.5. The total cross-sections in this kinematic region, assuming unpolarised production, are measured to be
ChemInform Abstract: P‐Stereogenic PNP Pincer‐Pd Catalyzed Intramolecular Hydroamination of Amino‐1,3‐dienes. (2015)

Abstract Allyl‐type chiral pyrrolidine derivatives are efficiently synthesized by asymmetric intramolecular hydroamination of amino‐1,3‐dienes with excellent regioselectivities and up to moderate enantioselectivities.
Diagnostika vrozených poruch imunity (2014)

Vcasna diagnostika vrozených poruch imunity umožňuje adekvatni cilenou lecbu a zabraněni infekcnim komplikacim. Poruchy tvorby protilatek jsou nejcastějsi. Imunoglobuliny a specificke protilatky jsou sniženy nebo chybi. Buněcne poruchy specificke imunity se projevi jako kombinovane T a B buněcne imunodeficience. Z těchto důvodů neinvazivni vysetřeni TREC a KREC z krevni kapky novorozenců zvýsi vcasný zachyt imunodeficienci. Děti, ktere jsou transplantovany do 3 měsiců věku, maji mnohem větsi sanci na přežiti, než děti transplantovane později.
Platelet-Derived Growth Factor Production by B16 Melanoma Cells Leads to Increased Pericyte Abundance in Tumors and an Associated Increase in Tumor Growth Rate (2004)

Platelet-derived growth factor (PDGF) receptor signaling participates in different processes in solid tumors, including autocrine stimulation of tumor cell growth, recruitment of tumor stroma fibroblasts, and stimulation of tumor angiogenesis. In the present study, the B16 mouse melanoma tumor model was used to investigate the functional consequences of paracrine PDGF stimulation of host-derived cells. Production of PDGF-BB or PDGF-DD by tumor cells was associated with an increased tumor growth rate. Characterization of tumors revealed an increase in pericyte abundance in tumors derived from B16 cells producing PDGF-BB or PDGF-DD. The increased tumor growth rate associated with PDGF-DD production was not seen in mice expressing an attenuated PDGF beta-receptor and was thus dependent on host PDGF beta-receptor signaling. The increased pericyte abundance was not associated with an increased tumor vessel density. However, tumor cell apoptosis, but not proliferation, was reduced in tumors displaying PDGF-induced increased pericyte coverage. Our findings thus demonstrate that paracrine PDGF production stimulates pericyte recruitment to tumor vessels and suggest that pericyte abundance influences tumor cell apoptosis and tumor growth.
Dramatic reduction of gate leakage current in 1.61 nm HfO 2 high-k dielectric poly-silicon gate with Al 2 O 3 capping layer (2002)

The electrical properties of poly-silicon gate MOS capacitors with HfO2 gate dielectric, with and without Al2O3 capping layer, were investigated. Without the capping layer, the experimental results show that an unacceptably high gate leakage current due to the interaction between HfO2 and poly-silicon was observed; while with a thin Al2O3 layer capping on 1.61 nm equivalent oxide thickness (EOT) HfO2 dielectric the gate leakage current density can be reduce to approximately 10−7 A/cm2, which is nearly seven orders (107) in magnitude lower than that of using pure oxide with identical EOT.
Integrating rock physics, PP-PS joint inversion and time-shifts to improve quantitative interpretation of time-lapse fluid and pressure changes (2021)

In this study, we show how to overcome the challenges of reliably estimating subtle 4D elastic property changes from seismic acquisitions just one year apart. We show that this is possible thanks to: 1) availability of highly repeatable seismic data and permanent reservoir monitoring (PRM); 2) the methodology for building 4D rock physics models that quantify 4D uncertainties related to seismic repeatability, 3) improving the quality of time-lapse estimates, especially at impedance S, due to the application of the 4D PP-PS joint inversion. This article summarizes the work of quantitative 4D interpretation by reporting how to build 4D rock physics models, how to estimate 4D elastic attributes (joint inversion of PP-PS data) and how the integrated interpretation of these results is performed. To validate the 4D interpretation, the results were compared to the production data from the injector and producer wells and to the outputs of the flow simulator. The integrated analysis shows how injection and production operations affect the reservoir properties, indicating preferred paths for water flow, the role of faults in reservoir hydraulic connectivity, regions where hydrocarbon production caused depletion, areas pressurized by water injection, and even the effect of the salinity contrast between the injection water and the brine. The application of this methodology allows updates to the simulation model that will affect future decisions.
13C chemical shielding in oxalic acid, oxalic acid dihydrate, and diammonium oxalate (1975)

13C chemical shielding tensors in three oxalates were investigated in order to determine the effects of protonation and conformation changes on the tensor elements and their orientations. The experimental results, together with those in the accompanying paper [R. G. Griffin and D. J. Ruben, J. Chem. Phys. elding) of σ22 and in one case a concurrent rotation of the tensor about σ33, the element which is perpendicular to the COO plane. On the other hand, the simple conformational change of the twisting of carboxyl groups relative to one another, which occurs in diammonium oxalate monohydrate, results in small rotation of the tensor around σ11 and also may contribute to a decrease in the shielding of the σ22 component in this molecule. The orientation of the 13C tensor in oxalic acid dihydrate is different from that observed in other oxalate ions and carboxyl groups. The influence of a change in hydrogen bonding strength on tensor elements is discussed.
Precision Immunotherapy of Cancer (2014)

The traditional cancer therapy triumvirate of chemotherapy, radiation, and surgery is today being augmented with vaccines, cytokines, antibodies, targeted small-molecule drugs, and cell-based therapies such as immunotherapy. The hope is that combination therapies involving immune-based approaches will greatly enhance long-term survival. This article provides an overview of genetically modified cancer therapy with T cells.
In situ processing methods for composite fuselage sandwich structures (1993)

Conventional sandwich structure fabrication methods are labor intensive and high in cost. A low cost method is needed to produce lightweight sandwich structures. Sundstrand has developed a series of in situ composite fabrication methods in which the raw materials (skin and core materials) are placed in a closed mold, and the component is produced in one heating cycle. Internal pressure is generated by chemical agents during the thermal cycles, which consolidates the skins and produces the foam core. The finished part is a net-shape composite sandwich structure with skins and a foamed core. The in situ process reduces cost by eliminating several secondary operations that are used in conventional fabrication methods. Further, a strong molecular bond is produced between the core and skin, which eliminates adhesive bonding and prevents a weak bond section in the sandwich structure. In this investigation, we evaluated the feasibility of the in situ process using thermoset materials currently under consideration for commercial airplane fuselage applications, such as keel sections. The materials used were Hercules 855340 toughened epoxy resin in both liquid and powder forms, and 3M Scotchply PR500 resin, manufactured by 3M Corporation, in powder form. We successfully foamed these resins and produced experimental panels with AS-4/855340 Hercules prepreg skins. Chopped fibers were added to the core to increase performance of the foam. Mechanical property testing on these panels showed properties competitive with other foams. Additional experiments are required to optimize the in situ foam core sandwiches for specific properties and applications.
Deep Model-Based Architectures for Inverse Problems Under Mismatched Priors (2022)

There is a growing interest in deep model-based architectures (DMBAs) for solving imaging inverse problems by combining physical measurement models and learned image priors specified using convolutional neural nets (CNNs). For example, well-known frameworks for systematically designing DMBAs include plug-and-play priors (PnP), deep unfolding (DU), and deep equilibrium models (DEQ). While the empirical performance and theoretical properties of DMBAs have been widely investigated, the existing work in the area has primarily focused on their performance when the desired image prior is known exactly. This work addresses the gap in the prior work by providing new theoretical and numerical insights into DMBAs under mismatched CNN priors. Mismatched priors arise naturally when there is a distribution shift between training and testing data, for example, due to test images being from a different distribution than images used for training the CNN prior. They also arise when the CNN prior used for inference is an approximation of some desired statistical estimator (MAP or MMSE). Our theoretical analysis provides explicit error bounds on the solution due to the mismatched CNN priors under a set of clearly specified assumptions. Our numerical results compare the empirical performance of DMBAs under realistic distribution shifts and approximate statistical estimators.
Augmented brain function by coordinated reset stimulation with slowly varying sequences (2015)

Several brain disorders are characterized by abnormally strong neuronal synchrony. Coordinated Reset (CR) stimulation was developed to selectively counteract abnormal neuronal synchrony by desynchronization. For this, phase resetting stimuli are delivered to different subpopulations in a timely coordinated way. In neural networks with spike timing-dependent plasticity CR stimulation may eventually lead to an anti-kindling, i.e., an unlearning of abnormal synaptic connectivity and abnormal synchrony. The spatiotemporal sequence by which all stimulation sites are stimulated exactly once is called the stimulation site sequence, or briefly sequence. So far, in simulations, pre-clinical and clinical applications CR was applied either with fixed sequences or rapidly varying sequences (RVS). In this computational study we show that appropriate repetition of the sequence with occasional random switching to the next sequence may significantly improve the anti-kindling effect of CR. To this end, a sequence is applied many times before randomly switching to the next sequence. This new method is called SVS CR stimulation, i.e., CR with slowly varying sequences. In a neuronal network with strong short-range excitatory and weak long-range inhibitory dynamic couplings SVS CR stimulation turns out to be superior to CR stimulation with fixed sequences or RVS.
Renal Protein Phosphatase 2A Activity and Spontaneous Hypertension in Rats (2000)

The impaired renal paracrine function of dopamine in spontaneously hypertensive rats (SHR) is caused by hyperphosphorylation and desensitization of the renal D(1) dopamine receptor. Protein phosphatase 2A (PP(2A)) is critical in the regulation of G-protein-coupled receptor function. To determine whether PP(2A) expression and activity in the kidney are differentially regulated in genetic hypertension, we examined the effects of a D(1)-like agonist, fenoldopam, in renal cortical tubules and immortalized renal proximal tubule cells from normotensive Wistar-Kyoto rats (WKY) and SHR. In cortical tubules and immortalized proximal tubule cells, PP(2A) expression and activities were greater in cytosol than in membrane fractions in both WKY and SHR. Although PP(2A) expressions were similar in WKY and SHR, basal PP(2A) activity was greater in immortalized proximal tubule cells of SHR than WKY. In immortalized proximal tubule cells of WKY, fenoldopam increased membrane PP(2A) activity and expression of the regulatory subunit PP(2A)-B56alpha, effects that were blocked by the D(1)-like antagonist SCH23390. Fenoldopam had no effect on cytosolic PP(2A) activity but decreased PP(2A)-B56alpha expression. In contrast, in immortalized proximal tubule cells of SHR, fenoldopam decreased PP(2A) activity in both membranes and cytosol but predominantly in the membrane fraction, without affecting PP(2A)-B56alpha expression; this effect was blocked by the D(1)-like antagonist SCH23390. We conclude that renal PP(2A) activity and expression are differentially regulated in WKY and SHR by D(1)-like receptors. A failure of D(1)-like agonists to increase PP(2A) activity in proximal tubule membranes may be a cause of the increased phosphorylation of the D(1) receptor in the SHR.
Evaluation of Rosa Species Accessions for Resistance to Eriophyid Mites1 (2019)

Abstract Rose rosette disease, caused by rose rosette virus (RRV), is an epidemic affecting nearly every rose cultivar in the United States. The only hosts for Phyllocoptes fructiphilus , the eriophyid mite that vectors RRV, are Rosa species. Eighteen Rosa species were evaluated for mite resistance by collecting foliage samples from July to November in 2016 and 2017, from which mites were extracted. Mites were isolated through a series of sieves and counted using a stereomicroscope. The response variable was expressed as the number of mites per gram of optimal rose tissue. Mite data were evaluated to determine the peak week for mite populations for each year. The mite populations varied by rose species (α = 0.05) in 2016 but not 2017. Due to high variability in mite counts, the species were not as clearly distinguishable as expected. This high variability is likely due to factors such as differential growth rates of the roses, weather, presence of RRV in the rose, and the quality of the tissue collected throughout the season. Experimental design revisions are proposed for future studies looking at Rosa species resistance to eriophyid mite populations. Index words: rose rosette virus, rose rosette disease, Phyllocoptes fructiphilus Keifer, virus, vector. Species used in this study: Phyllocoptes fructiphilus (Keifer), Prairie Rose [ Rosa arkansana (Porter), Forest Farm]; Carolina Rose [ Rosa carolina (L.), Forest Farm]; Rosa clinophylla (Thory), Rogue Valley Rose; White Prairie Rose [ Rosa foliolosa (Nutt.), Rogue Valley Rose]; White Prairie Rose [ Rosa foliolosa (Nutt.) Antique Rose Emporium]; Father Hugo Rose [ Rosa hugonis , Rogue Valley Rose]; Musk Rose [ Rosa moschata (J. Herrm.), Antique Rose Emporium]; Multiflora Rose [ Rosa multiflora (Thunb.)]; Shining Rose [ Rosa nitida (Willd.), Rogue Valley Rose]; Shining Rose [ Rosa nitida (Willd.), Antique Rose Emporium]; Nootka Rose [ Rosa nutkana (C. Presl.), Rogue Valley Rose]; Tea Rose [ Rosa odorata (Andrews), Foundation Plant Services, Davis, CA]; Swamp Rose [ Rosa palustris (Marshall), Antique Rose Emporium]; Swamp Rose [ Rosa palustris (Marshall), Ever Blooming Antique Rose Emporium]; Chestnut Rose [ Rosa roxburghii (Tratt.), Antique Rose Emporium]; ‘Plena' Chestnut Rose [ Rosa roxburghii (Tratt.), Rogue Valley Rose]; Rugosa Rose [ Rosa rugosa (Thunb.), Bailey's Nursery]; ‘Alba' Rugosa Rose [ Rosa rugosa (Thunb.), Bailey's Nursery]; Climbing Prairie Rose [ Rosa setigera (Michx.), Antique Rose Emporium]; Rosa soulieana (Crép.), Ralph Moore; Virginia Rose [ Rosa virginiana (Mill.), Forest Farm]; Porterfolia Memorial Rose [ Rosa wichuraiana (Crép.), Antique Rose Emporium]; Mountain Woods' Rose [Rosa woodsii (Lindl.), Rogue Valley Rose].
CDC Makwa hard red spring wheat (1992)

CDC Makwa is a hard red spring wheat (Triticum aestivum L.) cultivar which performs best in the Brown and Dark Brown soil zones of Saskatchewan and Alberta. CDC Makwa yields, on average, 3% more than Katepwa and is similar in maturity and quality.Key words: Cultivar description, Triticum aestivum L., wheat (spring)
Highly Efficient Two‐Step Synthesis of C‐sp3‐Centered Geminal Diiodides. (2005)

Abstract For Abstract see ChemInform Abstract in Full Text.