gebhart/patrepeval huggingface dataset:
Efficient Function Evaluations with Lookup Tables for Structured Matrix Operations (2007)

A hardware efficient approach is introduced for elementary function evaluations in certain structured matrix computations. It is a comprehensive approach that utilizes lookup tables for compactness, employs interpolations with adders and multipliers for their adaptivity to non-tabulated values and, more distinctively, exploits the function properties and the matrix structures to claim better control over numerical dynamic ranges. We demonstrate the effectiveness of the approach with simulation and synthesis results on evaluating, in particular, the cosine function, the exponential function and the zero-order Bessel function of the first kind.
Nucleotide depletion increases trafficking of gentamicin to the Golgi complex in LLC-PK1cells (2002)

Having shown rapid trafficking of aminoglycosides to the Golgi complex in cell culture, we focused on the injurious interaction that occurs when gentamicin administration is preceded by renal ischemia. Using Texas red-labeled gentamicin as a tracer, we determined that 15 min of cellular nucleotide depletion did not significantly increase subsequent uptake. However, cells previously depleted of nucleotides accumulated significantly more Texas red-labeled gentamicin within a dispersed Golgi complex. Using Ricinus communis and Lens culinaris lectins, which label specific compartments of the Golgi complex (trans-Golgi network/trans and medial/cis compartments, respectively), we determined that the medial/cis compartment dispersed after 15 min of nucleotide depletion but the trans-Golgi network/trans compartment remained unaffected. An increase in the number of cells exhibiting disrupted medial/cis-Golgi morphology after repletion in physiological media containing gentamicin was also seen. In summary, the increase in nephrotoxicity seen when ischemia precedes aminoglycoside uptake may be part of a complex mechanism initially involving increased Golgi accumulation and prolonged Golgi dispersion. The Golgi complex must then endure the effects of gentamicin accumulated in larger quantities in an aberrant physiological state.
Monolithic hybrid mode locked 1.3 &#x003BC;m semiconductor laser arrays (1989)

The first results for hybrid mode locking of semiconductor lasers are reported. Hybrid mode locking combines both active and passive mode locking to produce shorter mode-locked pulses. These functions are integrated into monolithic devices with a 1.3-μm GaInAsP gain region, an active waveguide, and a saturable absorber. The monolithic mode locked lasers are fabricated as arrays of six devices. These devices have low threshold currents and exhibit hysteresis in their light/current characteristics. The uniformity of threshold currents over an array of devices is very good. The long integrated waveguides allow mode locking at a repetition rate of 15 GHz without the need for an external cavity, with pulse widths as short as 1.4 ps being demonstrated.
Synthesis of Substituted Aromatic Compounds Using Ruthenium-Catalyzed Ring-Closing Metathesis (2009)

The demand for functionalized aromatic compounds is growing rapidly in many research fields. Therefore, the efficient synthesis of desired aromatic compounds is a critical issue in organic synthesis. In this account, we describe new synthetic approaches to versatile aromatic compounds, such as phenols, benzenes, 3-hydroxypyridines, and styrenes, by ring-closing olefin metathesis (RCM)/aromatization and ring-closing enyne metathesis (RCEM)/aromatization of acyclic precursors. The advantages in terms of simplicity, flexibility, and avoidance of the formation of regioisomers are proof of the versatility of this method for the synthesis of aromatic compounds.
LAPA, a 5 Gb/s modular pseudo-LVDS driver in 180 nm CMOS with capacitively coupled pre-emphasis (2018)

A pseudo-LVDS driver has been designed in a 180 nm technology for operation up to 5 Gb/s. It contains parallel main driver units based on an H-bridge circuit steering a current on an external load. The number of active units is adjustable, to reduce switching capacitance and static current, and hence power consumption, if a smaller current swing can be tolerated. Pre-emphasis is applied with a capacitively coupled charge-injection circuit. In the nominal condition with a steering current of 4 mA over a 100 $\Omega$ termination resistor, it consumes 30 mW from a 1.8 V supply.
Electronic transition inLa1−xSrxTiO3 (1999)

The transition with increasing x in ${\mathrm{La}}_{1\ensuremath{-}x}{\mathrm{Sr}}_{x}{\mathrm{TiO}}_{3}$ from an antiferromagnetic, p-type polaronic conductor to an n-type metal with an enhanced Pauli paramagnetism was investigated by monitoring changes in structure, magnetic properties, and, under different hydrostatic pressures, the resistance and thermoelectric power of ceramic samples. We conclude that ${\mathrm{LaTiO}}_{3}$ is an itinerant-electron antiferromagnet and the transition is first order with a phase separation associated with cooperative oxygen-atom displacements that segregate strongly correlated states from Fermi-liquid states. The N\'eel temperature ${T}_{N}\ensuremath{\approx}145\mathrm{K}$ decreases precipitously to 100 K at the phase limit $x=0.045\ifmmode\pm\else\textpm\fi{}0.005;$ the two-phase domain extends over the compositions $0.045&lt;~x&lt;~0.08.$
The Invention of New Radical Chain Reactions. Part XIII. High Yielding Decarboxylative Chalcogenation of Aliphatic and Alicyclic Acids (1987)

i a t i o n w i t h a tungsten lamp o f mixed anhydrides 1e.g.8) d e r i v e d from aliphatic o r aiicyclic c a r b o x y l i c acids and N-hydroxy-2p y r i d i n e thione 3 i n t h e presence o f a disuiphide.diselenide o r diteliuride gives t h e corresponding chalcogenide 1e.g. 9, 2, o r 111 in h i g h yield.T h e process involves a radical decarboxyiation followed b y SH2 reaction o f t h e intermediate carbon radical on the dichalcagenide.Access t o organic chalcogenides.especially seienides and tellurides.has generally been t h r o u g h ionic reactions such as, for example.nucleophiiic substitution b y a chalcogen containing nucleophile o r addition t o a nucieaphilic organochalcogen species.'Radical processes, in contrast, have not enjoyed a similar p o p u l a r i t y , p a r t l y because o f the relatively limited number o f preparatively useful sources o f carbon radicals compatible w i t h t h e various chalcogenating agents. 2 We have r e c e n t l y invented a mild method f o r generating carbon radicals from aliphatic and aiicyciic c a r b o x y l i c acids t h r o u g h a novel decarboxyiation reaction.3aThus, mixed anhydrides 1 d e r i v e d from suitable thiohydroxamic acids such as 1 o r 1 undergo a thermally o r photo-chemically induced decarboxylative rearrangement t o g i v e t h e corresponding sulphides 4. T h e reaction follows a simple radical chain mechanism as depicted in Scheme 1 (path A ) .T h e intermediate carbon radical produced is easily captured b y a v a r i e t y o f reagents allowing ' ~e d i c a t e d w i t h admiration and affection t o Professor G i l b e r t S t o r k on the occasion of his f i r s t s i x t y f i f t h b i r t h d a y .synthetically useful modifications o f the basic p r o c e ~s .~ Specifically we could perform an SH2 type reaction4 on a number of dichalcagenides which led to the synthesis o f sulphides, selenides and tellurides 6 i n preparatively acceptable yields.I n this overall decarboxylative chalcagenation.the co-produced chalcogenyl radical acts as a n efficient chain carrier [Scheme 1, path 01. 5 L RCO,' + R'X-S 2 P a t h B ------P a t h A ------Scheme 1These early experiments were carried out using thermal decomposition o f the esters of Z as radical source.However, large amounts of diphenyl disulphide and diphenyidiselenide had to be employed for the desired reaction to prevail over the background decarboxylative rearrangement which produces sulphide 4 through path A. This made work-up and purification quite tedious especially when the product and the reagent had similar polarities.Thus. to raise the yield o f phenyl sulphide to 74%. the reaction had to be conducted i n 30 equiv. of molten diphenyl disulphide [cf.Table 1, entries 1-31.I n the case o f selenides, smaller b u t nevertheless substantial, amounts of the more reactive diphenyl diselenide were
Diffusion behavior of anions in polyaniline during electrochemical undoping. 1. Dependence of diffusion coefficient of tetrafluoroborate on physical state of polyaniline (1991)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDiffusion behavior of anions in polyaniline during electrochemical undoping. 1. Dependence of diffusion coefficient of tetrafluoroborate on physical state of polyanilineKiyoshi Kanamura, Susumu Yonezawa, Shoji Yoshioka, and Zenichiro TakeharaCite this: J. Phys. Chem. 1991, 95, 20, 7939–7943Publication Date (Print):October 1, 1991Publication History Published online1 May 2002Published inissue 1 October 1991https://doi.org/10.1021/j100173a070RIGHTS & PERMISSIONSArticle Views159Altmetric-Citations11LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (1 MB) Get e-Alerts
Fumarate Hydratase Deletion in Pancreatic β Cells Leads to Progressive Diabetes (2017)

We explored the role of the Krebs cycle enzyme fumarate hydratase (FH) in glucose-stimulated insulin secretion (GSIS). Mice lacking Fh1 in pancreatic β cells (Fh1βKO mice) appear normal for 6-8 weeks but then develop progressive glucose intolerance and diabetes. Glucose tolerance is rescued by expression of mitochondrial or cytosolic FH but not by deletion of Hif1α or Nrf2. Progressive hyperglycemia in Fh1βKO mice led to dysregulated metabolism in β cells, a decrease in glucose-induced ATP production, electrical activity, cytoplasmic [Ca<sup>2+</sup>]<sub>i</sub> elevation, and GSIS. Fh1 loss resulted in elevated intracellular fumarate, promoting succination of critical cysteines in GAPDH, GMPR, and PARK 7/DJ-1 and cytoplasmic acidification. Intracellular fumarate levels were increased in islets exposed to high glucose and in islets from human donors with type 2 diabetes (T2D). The impaired GSIS in islets from diabetic Fh1βKO mice was ameliorated after culture under normoglycemic conditions. These studies highlight the role of FH and dysregulated mitochondrial metabolism in T2D.
Point-of-Care Fibrinogen Testing in Pregnancy (2018)

Agreement between estimated fibrinogen concentration via thromboelastography and traditional assays is not established in the parturient. We therefore recruited 56 parturients and performed Clauss and functional fibrinogen level (FLEV) tests. Mean difference of measurements was 36.8 mg/dL (95% CI, 21.8-51.9) with a standard deviation of 52.8 mg/dL. Calculated limits of agreement were 140.2 mg/dL (95% CI, 166.3-114.6) and -66.6 mg/dL (95% CI, -40.8 to -92.5), within the maximum allowable difference of 165 mg/dL. We therefore conclude that while most measurements fell within the limits of agreement, more work is needed to clearly define the role of this test in the obstetric population.
ChemInform Abstract: Selective, Zirconium‐Mediated Cross‐Coupling of Alkynes: Synthesis of Isomerically Pure 1,3‐Dienes and 1,4‐Diiodo‐1,3‐dienes. (1989)

Abstract The title reaction allows the one‐pot synthesis of 1,3‐dienes and 1,4‐diiodo‐1,3‐dienes such as (VIII) from alkyne precursors; in most cases, isomeric and chemical purities of &gt; 98% are obtained.
Flow distribution analysis by helical scanning in polysulfone hemodialyzers: Effects of fiber structure and design on flow patterns and solute clearances (2006)

The efficiency of a hemodialyzer is largely dependent on its ability to facilitate diffusion, as this is the main mechanism by which small solutes are removed. The diffusion process can be impaired if there is a mismatch between blood and dialysate flow distribution in the dialyzer. The objective of the paper was to study the impact of different fiber bundle configurations on blood and dialysate flow distribution and urea clearances. The Optiflux 200 NR hemodialyzer was studied and the standard F 80 A hemodialyzer was used as a control for the study. Six dialyzers of each type were studied in vitro in the radiology department utilizing a new generation of helical computed tomography (CT) scan following contrast medium injection into the blood and dialysate compartment. Dynamic sequential imaging of longitudinal sections of the dialyzer was undertaken to detect flow distribution, average and peak velocities, and calculate wall shear rates. Six patients were dialyzed with 2 different dialyzers in random consecutive sequence. In these patients, 2 consecutive dialyses were carried out with identical operational parameters (Qb = 300 mL/min, Qd = 500 mL/min). In each session, blood and dialysate side urea clearances were measured at 30 and 150 min of treatment. Macroscopic and densitometrical analysis revealed that flow distribution was most homogeneous in the dialyzer with a new bundle configuration. Significantly increased urea clearances (p < 0.001) were seen with the Optiflux dialyzer compared with the standard dialyzer. In conclusion, more homogeneous dialysate blood and dialysate flow distribution and improved small solute clearances can be achieved by modifying the configuration of the filter bundle. These effects are achieved probably as a result of reduced blood to dialysate mismatch with reduction of flow channeling. The used radiological technique allows detailed flow distribution analysis and has the potential for testing future modifications to dialyzer design.
A dual mode FPGA design for the hippocampal prosthesis (2012)

One important step towards the cognitive neural prosthesis design is to achieve real-time prediction of neuronal firing pattern. An FPGA-based hardware computational platform is designed to guarantee this hard real-time signal processing requirement. The proposed platform can work in dual modes: generalized Laguerre-Volterra model parameters estimation and output prediction, and can switch between these two important system functions. Compared with the traditional software-based platform implemented in C, the hardware platform achieves better efficiency in doing the biocomputations by up to thousandfold speedup in this process.
Thermo-Management in Neonatal Care: Future Needs (2013)

Pre-term babies are not able to efficiently maintain normothermia due to limited capacities of their regulation system dealing with changing environmental conditions. Typically immature neonates are very often hypotherm being associated with negative impact on survival rate. Thermal management of neonates can be difficult across the continuum of care in and outside hospitals due to conflicting targets in optimal thermal management versus patient care. This paper summarizes current clinical needs, state-of-art methods and future directions towards improved thermal management for these fragile patients.
A new, pressure-regulated balloon catheter for partial resuscitative endovascular balloon occlusion of the aorta (2020)

Russo, Rachel M. MD, MS; Franklin, Curtis J. BS; Davidson, Anders J. MD; Carlisle, Patricia L. PhD; Iancu, Ariella M. MSEd; Baer, David G. PhD; Alam, Hasan B. MD Author Information
Prodrugs based on phospholipid-nucleoside conjugates (2023)

The invention relates to the production of a single diastereomeric form of a phospholipid araC conjugate as a prodrug.
Organic metals: poly-(p-phenylene sulphide) hexafluoroarsenate (1980)

Electrically conducting p-type films, wires, and powders (ca. 1 Ω–1 cm–1) have been prepared by the AsF5 oxidation of poly-p-phenylene sulphide, the first melt- and solution-processible polymeric precursor to a conducting polymer.
A Reduced-Switching-Frequency Modulation Method for Hybrid MMCs Under Over-Modulation Conditions (2018)

A hybrid modular multilevel converter (MMC), consisting of full-bridge sub-modules (FBSMs) and half-bridge sub-modules (HBSMs), is an efficient and DC-fault tolerant topology, which can be used in overhead-line HVDC transmission application. Additionally, it can work under over-modulation condition (i.e., arm submodule clusters may generate negative voltage during a fundamental cycle) to improve the utilization of submodules (SMs). Regarding the over-modulation issue, this paper proposes a reduced-switching-frequency modulation method, considering the different dynamics of FBSMs and HBSMs, for hybrid MMCs. Moreover, an improved wave-distributing approach which can reduce losses and make the operating time and losses of the two types of SMs more even than the conventional method is presented. Finally, the effectiveness of the proposed method is verified by an over-modulation hybrid MMC simulation model built based on PSCAD/EMTDC platform.
Il mercato nell'Italia medievale (1995)

La revista Anales de la Universidad de Alicante. Historia Medieval, nació con el objetivo de crear un foro abierto de comunicación y debate sobre la investigación en el conocimiento del pasado medieval valenciano, hispánico, mediterráneo y europeo. Es una publicación digital de acceso abierto y gratuito.
Fatigue crack nucleation and growth in filled natural rubber (2003)

ABSTRACT Rubber components subjected to fluctuating loads often fail due to nucleation and the growth of defects or cracks. The prevention of such failures depends upon an understanding of the mechanics underlying the failure process. This investigation explores the nucleation and growth of cracks in filled natural rubber. Both fatigue macro‐crack nucleation as well as fatigue crack growth experiments were conducted using simple tension and planar tension specimens, respectively. Crack nucleation as well as crack growth life prediction analysis approaches were used to correlate the experimental data. Several aspects of the fatigue process, such as failure mode and the effects of R ratio (minimum strain) on fatigue life, are also discussed. It is shown that a small positive R ratio can have a significant beneficial effect on fatigue life and crack growth rate, particularly at low strain range.
Data from Validation of a Proliferation-Based Expression Signature as Prognostic Marker in Early Stage Lung Adenocarcinoma (2023)

&lt;div&gt;Abstract&lt;p&gt;&lt;b&gt;Purpose:&lt;/b&gt; New prognostic markers to guide treatment decisions in early stage non–small cell lung cancer are necessary to improve patient outcomes. In this report, we assess the utility of a predefined mRNA expression signature of cell-cycle progression genes (CCP score) to define 5-year risk of lung cancer–related death in patients with early stage lung adenocarcinoma.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Experimental Design:&lt;/b&gt; A CCP score was calculated from the mRNA expression levels of 31 proliferation genes in stage I and stage II tumor samples from two public microarray datasets [Director's Consortium (DC) and GSE31210]. The same gene set was tested by quantitative PCR in 381 formalin-fixed paraffin-embedded (FFPE) primary tumors. Association of the CCP score with outcome was assessed by Cox proportional hazards analysis.&lt;/p&gt;&lt;p&gt;&lt;b&gt;Results:&lt;/b&gt; In univariate analysis, the CCP score was a strong predictor of cancer-specific survival in both the Director's Consortium cohort (&lt;i&gt;P&lt;/i&gt; = 0.00014; HR = 2.08; 95% CI, 1.43–3.02) and GSE31210 (&lt;i&gt;P&lt;/i&gt; = 0.0010; HR = 2.25; 95% CI, 1.42–3.56). In multivariate analysis, the CCP score remained the dominant prognostic marker in the presence of clinical variables (&lt;i&gt;P&lt;/i&gt; = 0.0022; HR = 2.02; 95% CI, 1.29–3.17 in Director's Consortium, &lt;i&gt;P&lt;/i&gt; = 0.0026; HR = 2.16; 95% CI, 1.32–3.53 in GSE31210). On a quantitative PCR platform, the CCP score maintained highly significant prognostic value in FFPE-derived mRNA from clinical samples in both univariate (&lt;i&gt;P&lt;/i&gt; = 0.00033; HR = 2.10; 95% CI, 1.39–3.17) and multivariate analyses (&lt;i&gt;P&lt;/i&gt; = 0.0071; HR = 1.92; 95% CI, 1.18–3.10).&lt;/p&gt;&lt;p&gt;&lt;b&gt;Conclusions:&lt;/b&gt; The CCP score is a significant predictor of lung cancer death in early stage lung adenocarcinoma treated with surgery and may be a valuable tool in selecting patients for adjuvant treatment. &lt;i&gt;Clin Cancer Res; 19(22); 6261–71. ©2013 AACR&lt;/i&gt;.&lt;/p&gt;&lt;/div&gt;
UMTS Security Features in Release 1999 (2003)

This chapter contains sections titled: Access Security to UMTS Interworking with GSM Additional Security Features in Release 1999
Stimulation of fungal spore germination by volatiles from aged seeds (1978)

Alaska pea seeds were stored asceptically or with inoculum of Aspergillus ruber, a pathogenic storage fungus, under conditions which induce rapid seed deterioration and permit infection of seeds by A. ruber (30 °C and 92% relative humidity). Volatiles from germinating aged seeds stimulated germination of conidiospores of Fusarium solani f. sp. pisi and Alternaria alternata and chlamydospores of F. solani f. sp. pisi, all in soil-induced stasis, much more than volatiles from unaged seeds. Volatiles from A. ruber - infected seeds were more stimulatory than from comparably aged noninfected seeds when planted in sand, but this effect was not seen when the seeds were planted in soil. Oospores of Pythium ultimum were not stimulated to germinate by volatiles from any seeds. Aged and infected seeds produced up to 24 times more carbonyl compounds than unaged seeds, presumably as a consequence of lipid peroxidation.
The Measured Electric Field Spatial Distribution Within A Metamaterial Subwavelength Cavity Resonator (2007)

Through experimental investigation, a thin subwavelength cavity resonator was physically realized using a bilayer structure composed of air and a negative permeability metamaterial structure one unit cell in thickness. We designed and built the metamaterial slab with periodic metallic ring structures and measured the spatial electric field magnitude in a cavity formed from this slab and a region of air, showing that a subwavelength cavity can be realized. The measured electric field magnitude distribution in the cavity matched very well with effective medium theory, showing that even a slab one unit cell in thickness may be effectively equivalent to a thin homogeneous medium as far as the construction of a sub-wavelength cavity is concerned, provided that the unit cell size is significantly smaller than the free space wavelength.