gebhart/patrepeval huggingface dataset:
LDP End-of-LIB (2007)

There are situations following LDP session establishment where it
would be useful for an LDP speaker to know when its peer has
advertised all of its labels. These include session establishment
when LDP-IGP sync is in use and session re-establishment following
loss of an LDP session when LDP graceful restart is in use. The LDP
specification provides no mechanism for an LDP speaker to notify a
peer when it has completed its initial label advertisements to that
peer. This document specifies means for an LDP speaker to signal
completion of its initial label advertisements following session
establishment.
PCA of high dimensional random walks with comparison to neural network\n training (2018)

One technique to visualize the training of neural networks is to perform PCA\non the parameters over the course of training and to project to the subspace\nspanned by the first few PCA components. In this paper we compare this\ntechnique to the PCA of a high dimensional random walk. We compute the\neigenvalues and eigenvectors of the covariance of the trajectory and prove that\nin the long trajectory and high dimensional limit most of the variance is in\nthe first few PCA components, and that the projection of the trajectory onto\nany subspace spanned by PCA components is a Lissajous curve. We generalize\nthese results to a random walk with momentum and to an Ornstein-Uhlenbeck\nprocesses (i.e., a random walk in a quadratic potential) and show that in high\ndimensions the walk is not mean reverting, but will instead be trapped at a\nfixed distance from the minimum. We finally compare the distribution of PCA\nvariances and the PCA projected training trajectories of a linear model trained\non CIFAR-10 and ResNet-50-v2 trained on Imagenet and find that the distribution\nof PCA variances resembles a random walk with drift.\n
GLA/DRST real-world outcome analysis of CAR-T cell therapies for large B-cell lymphoma in Germany (2022)

CD19-directed chimeric antigen receptor (CAR) T cells have evolved as a new standard-of-care (SOC) treatment in patients with relapsed/refractory (r/r) large B-cell lymphoma (LBCL). Here, we report the first German real-world data on SOC CAR T-cell therapies with the aim to explore risk factors associated with outcomes. Patients who received SOC axicabtagene ciloleucel (axi-cel) or tisagenlecleucel (tisa-cel) for LBCL and were registered with the German Registry for Stem Cell Transplantation (DRST) were eligible. The main outcomes analyzed were toxicities, response, overall survival (OS), and progression-free survival (PFS). We report 356 patients who received axi-cel (n = 173) or tisa-cel (n = 183) between November 2018 and April 2021 at 21 German centers. Whereas the axi-cel and tisa-cel cohorts were comparable for age, sex, lactate dehydrogenase (LDH), international prognostic index (IPI), and pretreatment, the tisa-cel group comprised significantly more patients with poor performance status, ineligibility for ZUMA-1, and the need for bridging, respectively. With a median follow-up of 11 months, Kaplan-Meier estimates of OS, PFS, and nonrelapse mortality (NRM) 12 months after dosing were 52%, 30%, and 6%, respectively. While NRM was largely driven by infections subsequent to prolonged neutropenia and/or severe neurotoxicity and significantly higher with axi-cel, significant risk factors for PFS on the multivariate analysis included bridging failure, elevated LDH, age, and tisa-cel use. In conclusion, this study suggests that important outcome determinants of CD19-directed CAR T-cell treatment of LBCL in the real-world setting are bridging success, CAR-T product selection, LDH, and the absence of prolonged neutropenia and/or severe neurotoxicity. These findings may have implications for designing risk-adapted CAR T-cell therapy strategies.
Distinct ventral stream and prefrontal cortex representational dynamics during sustained conscious visual perception (2023)

Instances of sustained stationary sensory input are ubiquitous. However, previous work focused almost exclusively on transient onset responses. This presents a critical challenge for neural theories of consciousness, which should account for the full temporal extent of experience. To address this question, we use intracranial recordings from ten human patients with epilepsy to view diverse images of multiple durations. We reveal that, in sensory regions, despite dramatic changes in activation magnitude, the distributed representation of categories and exemplars remains sustained and stable. In contrast, in frontoparietal regions, we find transient content representation at stimulus onset. Our results highlight the connection between the anatomical and temporal correlates of experience. To the extent perception is sustained, it may rely on sensory representations and to the extent perception is discrete, centered on perceptual updating, it may rely on frontoparietal representations.
CIGS photovoltaic integrated circuits from solution-deposited precursors (2009)

Selenide (CIGS) obtained with the unique combination of low-cost solution-based precursor deposition and a reactive transfer printing method. This approach provides reduced capital costs compared to vacuum deposition approaches, low thermal budget, high throughput, control of crystallographic orientation, and very high device quality materials.
Combinatorial Chemistry in Steroid Receptor Drug Discovery (2003)

Combinatorial chemistry has significantly increased the speed of small molecule lead discovery and optimization for multiple targets in the pharmaceutical industry. Large libraries of bioactive compounds, synthesized either as mixtures or discreet units, can now be made using solid- or solution-phase techniques (1-4). The design of the libraries can be biased toward a specific lead structure, enabling the rapid dissemination of information about the compound of interest (5,6). This chapter describes the methods developed for the application of combinatorial chemistry to the solid-phase synthesis of steroid receptor ligands.
A 3.0 TFLOPS 0.62V Scalable Processor Core for High Compute Utilization AI Training and Inference (2020)

A processor core is presented for AI training and inference products. Leading-edge compute efficiency is achieved for robust fp16 training via efficient heterogeneous 2-D systolic array-SIMD compute engines leveraging compact DLFloat16 FPUs. Architectural flexibility is maintained for very high compute utilization across neural network topologies. A modular dual-corelet architecture with a shared scratchpad and a software-controlled network/memory interface enables scalability to many-core SoCs and large-scale systems. The 14nm AI core achieves fp16 peak performance of 3.0 TFLOPS at 0.62V and 1.4 TFLOPS/W at 0.54V.
Endocrine Disruptors (Environmental Estrogens) Enhance Autoantibody Production by B1 Cells (2004)

Accumulating data suggest that endocrine disruptors affect not only the reproductive system, but also the immune system. We demonstrate here that endocrine disruptors including diethylstilbestrol (DES) and bisphenol-A (BPA) enhance autoantibody production by B1 cells both in vitro and in vivo. BWF1 mice, a murine model for systemic lupus erythematosus (SLE), implanted with Silastic tubes containing DES after orchidectomy developed murine lupus characterized by immunoglobulin G (IgG) anti-DNA antibody production and IgG deposition in the glomeruli in the kidney as well as those implanted with 17beta-estradiol (E2). Plaque-forming cells (PFC) producing autoantibodies specific for bromelain-treated red blood cells were significantly increased in mice implanted with DES and BPA. IgM antibody production by B1 cells in vitro was also enhanced in the presence of endocrine disruptors including DES and BPA. Estrogen receptor (ER) expression was upregulated in B1 cells in aged BWF1 mice that developed lupus nephritis. These results suggest that endocrine disruptors are involved in autoantibody production by B1 cells and may be an etiologic factor in the development of autoimmune diseases.
Das mykotische Aneurysma der infrarenalen Aorta: chirurgische Moglichkeiten und Resultate. [Mycotic aneurysm of the infrarenal aorta: surgical possibilities and results] (1992)

Between 1973 and 1990 eleven patients with mycotic aneurysm of the abdominal aorta underwent surgery. Extra-anatomic axillobifemoral bypass with aortic ligation and aneurysm excision was performed in 5 patients, and in situ reconstruction in 6. There were 3 early and 3 late deaths. Regardless of the type of operation, surgery of mycotic aneurysm is followed by severe postoperative complications with high the early and the late mortality rates.
Ultralow Power Silicon Microdisk Modulators and Switches. (2016)

Abstract not provided.
Somatostatin Inhibits the Dermorphin-Stimulated Thyrotropin Release in Man (1986)

We have studied the effect of the intravenous administration of somatostatin (SRIF) on the thyrotropin (TSH) response to intravenous dermorphin (D), a new potent opioid peptide, in 7 healthy men. D significantly increased the serum TSH concentration. SRIF administration prior to, during and after D completely prevented the D-induced rise in serum TSH. These results confirm that D stimulates TSH release in man and that this stimulatory effect can be prevented by SRIF.
Correction to Adsorption and Separation of CO2 on KFI Zeolites: Effect of Cation Type and Si/Al Ratio on Equilibrium and Kinetic Properties (2014)

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionORIGINAL ARTICLEThis notice is a correctionCorrection to Adsorption and Separation of CO2 on KFI Zeolites: Effect of Cation Type and Si/Al Ratio on Equilibrium and Kinetic PropertiesTom Remy, Sunil A. Peter, Leen Van Tendeloo, Stijn Van der Perre, Yannick Lorgouilloux, Christine E. A. Kirschhock, Johan A. Martens, Yanliang Xiong, Gino V. Baron, and Joeri F. M. Denayer*Cite this: Langmuir 2014, 30, 10, 2968Publication Date (Web):March 5, 2014Publication History Published online5 March 2014Published inissue 18 March 2014https://pubs.acs.org/doi/10.1021/la500366nhttps://doi.org/10.1021/la500366ncorrectionACS PublicationsCopyright © 2014 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views588Altmetric-Citations3LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (104 KB) Get e-Alertsclose Get e-Alerts
1609: Intraoperative Assessment of an Implantable Electrode Array for Cavernous Nerve Stimulation (2006)

You have accessJournal of UrologyDiscussed Poster, Wednesday, May 24, 2006, 1:00 - 4:00 pm1 Apr 20061609: Intraoperative Assessment of an Implantable Electrode Array for Cavernous Nerve Stimulation Arthur L. Burnett, Francesco Montorsi, and Alberto Bringanti Arthur L. BurnettArthur L. Burnett More articles by this author , Francesco MontorsiFrancesco Montorsi More articles by this author , and Alberto BringantiAlberto Bringanti More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)33801-1AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "1609: Intraoperative Assessment of an Implantable Electrode Array for Cavernous Nerve Stimulation." The Journal of Urology, 175(4S), p. 518 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 518 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Arthur L. Burnett More articles by this author Francesco Montorsi More articles by this author Alberto Bringanti More articles by this author Expand All Advertisement Loading ...
High performance microring resonator (MRR)-based optical filter with reduced group delay and simplified center-wavelength control (2013)

We present a new microring resonator (MRR)-based optical filter that takes advantage of the improvements that can be gained from cascading two (or more) MRR elements while physically using only one MRR element due to its unique looped-back configuration. This approach avoids the costly problem associated with dynamic control of matching (or aligning) the center-wavelengths coming from the two MRR elements. This new optical filter is a generalization of our previously reported filter (called <strong>LOBOUR</strong>) based on the <strong>C</strong>ascaded <strong>O</strong>ver- and <strong>U</strong>nder-coupling <strong>R</strong>esonator (<strong>COUR</strong>) architecture. Here, we compare the performance of our filter to four different configurations under the following criteria: (1) lower group delay (GD), and (2) simplified solution to wavelength-drift problem, (3) lower power consumption, (4) narrower linewidth, and (5) better extinction ratio (ER).
Arthroscopic Debridement in the Treatment of Patients With Isolated Tears of the Subscapularis (2006)

Level IV, therapeutic case series.
Connecting Tolerancing of Freeform Surface Deformation in Illumination Optics with the Laplacian Magic Mirror (2021)

This paper presents a methodology for illumination optics tolerancing. Specifically, we investigate tolerancing deformation of a freeform surface under a point source illumination. Through investigation, we learn about several surface-deformation characteristics that build tolerancing intuitions. First, we show that positive and negative irradiance changes occur together as a consequence of flux conservation. Then, we demonstrate a linear relationship between the steepness of the surface perturbation and the magnitude of the irradiance change. Lastly, we recognize that the Laplacian Magic Mirror concept (M. V. Berry, Eur J Phys 27, 2006) can be expanded to surface deformation tolerancing. Utilizing these surface deformation characteristics, we propose a fast and predictable tolerancing method that eliminates a significant portion of the ray-tracing time.
Hybrid Reference Signal Multiplexing Using Combination of Block Spread and Cyclic Shift CDMA for Uplink Control Signals in DFT-Precoded OFDMA (2011)

This paper proposes a hybrid reference signal (RS) multiplexing scheme that employs a block spread (BS) and cyclic shift (CS) combination for the physical uplink control channel (PUCCH) in the Long-Term Evolution (LTE) uplink. In the proposed scheme, we give higher priority to BS multiplexing over the FFT blocks assigned to a RS within a slot than CS multiplexing. Hence, accurate channel estimation for coherent detection is achieved by shortening the despread interval in the frequency domain compared to the original multiplexing scheme using only CS to extract the channel estimate of each code channel. Computer simulation results show that, assuming the use of channel quality indicator (CQI) bits, the average received signal-to-noise power ratio (SNR) satisfying the required average block error rate when employing the proposed hybrid RS multiplexing is decreased compared to that for conventional RS multiplexing using only CS when the root mean square delay spread is longer than approximately 0.5 μsec particularly for a large number of multiplexed PUCCHs such as 12.
Cyclic lipopeptide profile of three Bacillus subtilis strains; antagonists of Fusarium head blight (2011)

The objective of the study was to identify the lipopetides associated with three Bacillus subtilis strains. The strains are antagonists of Gibberella zeae, and have been shown to be effective in reducing Fusarium head blight in wheat. The lipopeptide profile of three B. subtilis strains (AS43.3, AS43.4, and OH131.1) was determined using mass spectroscopy. Strains AS43.3 and AS43.4 produced the anti-fungal lipopeptides from the iturin and fengycin family during the stationary growth phase. All three strains produced the lipopeptide surfactin at different growth times. Strain OH131.1 only produced surfactin under these conditions. The antifungal activity of the culture supernatant and individual lipopeptides was determined by the inhibition of G. zeae. Cell-free supernatant from strains AS43.3 and AS43.4 demonstrated strong antibiosis of G. zeae, while strain OH131.1 had no antibiosis activity. These results suggest a different mechanism of antagonism for strain OH131.1, relative to AS43.3 and AS43.4.
Serous Cystadenoma of the Pancreas: Potentials and Pitfalls of a Preoperative Cytopathologic Diagnosis (2016)

A cytopathologic diagnosis of SCA on FNA is extremely difficult. The salient cytomorphologic features for identifying SCAs included scant cellularity, a mostly clear background, absence of extracellular mucin, hemosiderin-laden macrophages, and loose fragments of cuboidal cells with a notable absence of necrosis, atypia, and mitoses.
A 0.54pJ/b 20Gb/s ground-referenced single-ended short-haul serial link in 28nm CMOS for advanced packaging applications (2013)

Laminated packages, silicon interposer substrates, and special-purpose package-to-package interconnect, together with 3D stacking of silicon components enable systems with greatly improved computational power, memory capacity and bandwidth. These package options offer very high-bandwidth channels between chips on the same substrate. We employ ground-referenced single-ended signaling, a charge-pump transmitter, and a co-designed channel to provide communication between multiple chips on one package with high bandwidth per pin and low energy per bit.
Expansion in Exponential Sums with Application to Discrete Complex Image Theory (2022)

Expansion of functions in terms of exponential sums is a technique that has been used in the past for applications in applied mathematics such as number theory. However, the technique also has interesting applications in the field of engineering. In this paper we present a novel approach to deriving an expansion of a function as an exponential sum and show how this expansion can be applied to the Sommerfeld Integral to give a novel Discrete Complex Image representation.
An experimental and computational study of beam-steering of parametric array (2014)

A parametric array is a nonlinear conversion process that can generate a highly directional sound beam with a small aperture. It is expected that electrical beam steering of directional sound beams generated by the parametric array may be useful in many applications such as ultrasonic raging sensors or directional loudspeakers in air. One of the major issues of beam steering of the parametric array is to precisely predict the steered difference frequency wave field in the medium. In this study, beam steering of the parametric array is computed by using a time-domain numerical code that solves the Khokhlov-Zabolotskaya-Kuznetsov equation. Since it is impossible to compute the exact difference wave field due to a complex primary source distribution in the medium, a simplified numerical model is proposed. The computed result is compared with the experimental result. For experimental study, 16-channel piezoelectric micromachined ultrasonic transducer array, which consists of two resonant type unit drivers to generate bi-frequency primary waves (f1 = 100 kHz and f2 = 140 kHz), was designed, fabricated, and tested. The beam patterns of the primary and difference frequency waves were measured and compared with the computed result while applying complex weighting to each channel. [Work supported by ADD (UD130007DD).]
Epitaxy of new layered materials: 2D chalcogenides and challenges of weak van der Waals interactions (2020)

The application of new materials in nanotechnology opens new perspectives and enables ground-breaking innovations. Two-dimensional van der Waals materials and more specific, 2D chalcogenides are a promising class of new materials awaiting their usage in the semiconductor industry. However, the integration of van der Waals materials relying on industry-compatible manufacturing processes is still a major challenge. This is currently restricting the application of these new materials to the research laboratories environment only. The large-area and single-crystalline growth of van der Waals materials is one of the most important requirements to meet the challenging demands implied by the semiconductor industry. This review contributes to a more generalized understanding on the integration of van der Waals materials - and in more specific 2D chalcogenides - through the growth process of epitaxy. This, can pursue further the aspiration of large-area, single-crystalline and defect-free epitaxial integration of (quasi) van der Waals homo- and heterostructures into the great world of the semiconductor industry.
Strategy for Development of Respiratory and Gastrointestinal Tract Viral Vaccines in the 1980s (1981)

Journal Article Strategy for Development of Respiratory and Gastrointestinal Tract Viral Vaccines in the 1980s Get access Robert M. Chanock Robert M. Chanock Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland Please address requests for reprints to Dr. Robert M. Chanock, National Institutes of Health, Building 7, Room 301, Bethesda, Maryland 20205. Search for other works by this author on: Oxford Academic PubMed Google Scholar The Journal of Infectious Diseases, Volume 143, Issue 3, March 1981, Pages 364–374, https://doi.org/10.1093/infdis/143.3.364 Published: 01 March 1981
PARQR (2020)

As enrollment numbers in online courses increase, students, instructors, and teaching assistants have difficulty finding needed information in online forums because of the number of posts, resulting in duplicate posts that exacerbate the problem. We introduce PARQR, a recommendation tool that suggests relevant contributions as participants compose their posts. We investigate the use of PARQR in five online degree-seeking courses. We survey 74 students and interview five teaching assistants to understand their experience with online forums and PARQR. We compare the differences between using and not using PARQR for an online course assignment. PARQR users found the tool to be useful for navigating online forums, and PARQR was effective in reducing the number of posts (0.291 vs. 0.506 posts per active student) and duplicate posts (17.8% vs. 25.6%) in an online course. These results suggest that PARQR makes on-line forums more efficient for users to find needed information.