gebhart/patrepeval huggingface dataset:
Robust Cache-Aided Interference Management Under Full Transmitter Cooperation (2018)

In this paper, we look at a wireless network consisting of K fully-cooperating transmitters serving K receivers, each equipped with a cache memory. Each node is equipped with a single antenna and transmitters have access to partial channel state information. For a symmetric setting, we characterize the generalized degrees of freedom (GDoF) up to a constant multiplicative factor. We further show that the characterized order-optimal GDoF is also attained in a decentralized setting, with no coordination during the cache content placement phase.
Plasma-assisted molecular beam epitaxy growth diagram of InGaN on (0001)GaN for the optimized synthesis of InGaN compositional grades (Phys. Status Solidi B 4/2016) (2016)

InGaN alloys have been attracting tremendous interest because of the large range of wavelengths covered when tuning the In to Ga ratio, offering extensive band gap engineering possibilities as well as the opportunity to achieve longer wavelength optoelectronic devices. Industrialization of InGaN materials with large In contents is however still limited by challenges imposed by intrinsic material properties. At typical InGaN growth temperatures the In desorption rate is lower than the In–N bond decomposition rate, making it difficult to avoid accumulation of metal In droplets on the surface. Hestroffer et al. (pp. 626–629) have established a growth diagram for InGaN grown on (0001) GaN at a constant temperature of 575 °C versus Ga and In fluxes. The authors identify different regimes, namely: N-rich, intermediate In-rich, droplet-accumulation In-rich, and Ga-rich. Compositionally graded InGaN layers are grown by ramping the In and Ga fluxes in parallel under two distinct growth regimes. Structural and optical properties of the two types of grades are compared. The growth diagram proves to be a useful tool in controlling the metal fluxes and thereby the stoichiometry conditions on the surface during the growth of compositionally graded layers.
Exploiting Diversity in Future Generation Satellite Systems with Optical Feeder Links (2016)

peer reviewed
Some factors affecting bubble formation with catheter-mediated defibrillator pulses. (1986)

Factors affecting bubble formation during delivery of defibrillator pulses to arrhythmogenic cardiac tissue via a catheter are unknown. We investigated the role of energy, electrode surface area, interelectrode distance, and electrode polarity on bubble formation and on current and voltage waveforms during delivery of damped sinusoidal discharges from a standard defibrillator to anticoagulated bovine blood. Gas composition was studied with mass spectrometry. Defibrillator energy settings were varied between 5 and 360 J. The principal catheter used for study was a Medtronic 6992A lead. Additional electrodes tested included 2, 5, and 10 mm long No. 6F, 7F, and 8F copper electrodes. Interelectrode distances used to assess the effect of anode-cathode spacing were 1, 5, 10, and 20 cm. Bubble volume increased linearly from 0.043 to 0.134 ml per cathodal pulse and from 0.030 to 3.50 ml per anodal pulse as energy settings were increased from 5 to 360 J (r = .99). Typical smooth waveforms for both current and voltage were seen only in the absence of bubbles. The voltage waveform was distorted for each cathodal pulse of 100 J or more and for each anodal pulse of 10 J or more only if bubbles were present. The effect of electrode surface area on bubble formation was tested at a 200 J energy setting and at a 10 cm interelectrode distance with the use of cathodal pulses. Bubble formation varied inversely with electrode surface area (r = .876). Bubble formation, however, varied minimally as interelectrode spacing was changed from 1 to 20 cm. The effect of polarity on bubble formation when the Medtronic 6992A distal electrode and an 8.5 cm disk electrode separated by 10 cm were used was highly significant. For a 200 J pulse, bubble formation with the catheter as anode was 3.30 +/- 0.10 ml and with the catheter as cathode it was 0.070 +/- 0.002 ml (p less than .001). Mass spectrometry of both anodal and cathodal gas samples demonstrated the constituents of the gas bubble to include a variety of gases, which is inconsistent with simple electrolytic production of the bubbles observed. The predominance of nitrogen in either polarity sample suggested that the principal source of the bubble was dissolved air. In summary, bubble formation at an electrode receiving damped sinusoidal outputs from a standard defibrillator does not vary significantly with varying interelectrode distance. However, it is directly proportional to energy and inversely proportional to electrode surface area. Anodal catheter discharges produce considerably more bubbles than do cathodal discharges.(ABSTRACT TRUNCATED AT 400 WORDS)
Diagnostic value of whole-body MRI with diffusion-weighted sequence for detection of peritoneal metastases in colorectal malignancy (2018)

WB-DWI accurately predicted PCI before surgery in patients undergoing evaluation for cytoreductive surgery.
New frontiers for the materials genome initiative (2019)

Abstract The Materials Genome Initiative (MGI) advanced a new paradigm for materials discovery and design, namely that the pace of new materials deployment could be accelerated through complementary efforts in theory, computation, and experiment. Along with numerous successes, new challenges are inviting researchers to refocus the efforts and approaches that were originally inspired by the MGI. In May 2017, the National Science Foundation sponsored the workshop “Advancing and Accelerating Materials Innovation Through the Synergistic Interaction among Computation, Experiment, and Theory: Opening New Frontiers” to review accomplishments that emerged from investments in science and infrastructure under the MGI, identify scientific opportunities in this new environment, examine how to effectively utilize new materials innovation infrastructure, and discuss challenges in achieving accelerated materials research through the seamless integration of experiment, computation, and theory. This article summarizes key findings from the workshop and provides perspectives that aim to guide the direction of future materials research and its translation into societal impacts.
HIV / AIDS and the law: a resource manual. (1997)

This manual analyzes and presents the human rights ethical and legal principles that apply to HIV/AIDS in South Africa. It will serve as a vital tool for information education and advocacy by human rights activists AIDS service organizations networks of people living with HIV/AIDS government officials people in business trade unions educators the media and other partners. Chapter 1 of this manual is a brief description of HIV/AIDS and its modes of transmission. Chapter 2 then describes the legal system of South African in a manner that can easily be understood by the nonlawyer. Chapter 3 introduces the Bill of rights and highlights the “Equality Clause”. Chapters 4 5 6 7 8 and 9 provide detailed explanations of the medical rights of patients workers women lesbians gays youths and children and prisoners. Furthermore the following chapters focus on the social support for people living with HIV/AIDS; HIV/AIDS and insurance law; future planning; understanding criminal law; and legal remedies. Finally the manual describes how to use all the information provided to obtain legal remedies and to protect ones rights.
PET of vascular endothelial growth factor receptor expression. (2006)

Successful demonstration of the ability of (64)Cu-DOTA-VEGF(121) to visualize VEGFR expression in vivo may allow for clinical translation of this radiopharmaceutical for imaging tumor angiogenesis and guiding antiangiogenic treatment, especially patient selection and treatment monitoring of VEGFR-targeted cancer therapy.
CST does not evict elongating telomerase but prevents initiation by ssDNA binding (2021)

The CST complex (CTC1-STN1-TEN1) has been shown to inhibit telomerase extension of the G-strand of telomeres and facilitate the switch to C-strand synthesis by DNA polymerase alpha-primase (pol α-primase). Recently the structure of human CST was solved by cryo-EM, allowing the design of mutant proteins defective in telomeric ssDNA binding and prompting the reexamination of CST inhibition of telomerase. The previous proposal that human CST inhibits telomerase by sequestration of the DNA primer was tested with a series of DNA-binding mutants of CST and modeled by a competitive binding simulation. The DNA-binding mutants had substantially reduced ability to inhibit telomerase, as predicted from their reduced affinity for telomeric DNA. These results provide strong support for the previous primer sequestration model. We then tested whether addition of CST to an ongoing processive telomerase reaction would terminate DNA extension. Pulse-chase telomerase reactions with addition of either wild-type CST or DNA-binding mutants showed that CST has no detectable ability to terminate ongoing telomerase extension in vitro. The same lack of inhibition was observed with or without pol α-primase bound to CST. These results suggest how the switch from telomerase extension to C-strand synthesis may occur.
On Adaptive Identity Management: The Next Generation of Identity Management Technologies (2003)

Identity management plays a key role in enabling personal, business and government activities along with interactions and transactions in the digital world. The &amp;quot;chapter 1&amp;quot; of identity management is about the current paradigm, i.e., multiple, slightly integrated products and solutions for relatively static, closed and well controlled environments.
A fabrication process for integrating polysilicon microstructures with post-processed CMOS circuits (2000)

A MEMS-first fabrication process for integrating CMOS circuits with polysilicon micromechanical structures is described in detail. The overall process uses 18 masks (22 lithography steps) to merge a p-well LOCOS CMOS process that has one metal and two polysilicon layers with a surface micromachining process that has three layers of polysilicon. The microstructures are formed within recesses on the surface of silicon wafers such that their uppermost surfaces are coplanar with the remainder of the substrate. No special planarization technique, such as chemical-mechanical polishing, is used in the work described here. Special aspects of the process include provisions to improve lithography within the recesses, to protect the microstructures during the circuit fabrication, and to implement an effective lead transfer between the microstructures and the on-chip circuitry. The process is validated using a test vehicle that includes accelerometers and gyroscopes interfaced with sensing circuits. Measured transistor parameters match those obtained in standard CMOS, with NMOS and PMOS thresholds at 0.76 V and -0.96 V, respectively.
CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer (2012)

Aberrant promoter region hypermethylation of upstream transcription factors may be responsible for silencing entire anti-neoplastic gene networks. In this study, we explored whether transcription factor coding gene, caudal-related homeobox 2 (CDX2), is silenced by promoter hypermethylation in lung cancer, and examined its potential tumor-suppressive functions. Semi-quantitative RT-PCR showed that four of six lung cancer cell lines exhibited no or weak CDX2 expression. Expression of CDX2 was correlated to CDX2 promoter region methylation status, as determined by methylation-specific PCR (MSP) and bisulfite sequencing. Restoration of CDX2 expression was induced by treatment with demethylating drug 5-aza-2'-deoxycytidine (5-AZA) in lung cancer cell lines. Methylation of CDX2 was common in human primary lung cancer (61 of 110 tumors, 55.45%), but no methylation was found in normal lung tissues. Re-expression of CDX2 suppressed lung cancer cell proliferation and blocked cells in G1 phase. β-catenin/TCF activity and downstream genes expression were inhibited by re-expression of CDX2, and increased by depletion of CDX2. In conclusion, CDX2 is frequently methylated in lung cancer, and expression of CDX2 is regulated by promoter region hypermethylation. CDX2 may serve as a tumor suppressor in lung cancer and inhibits lung cancer cell proliferation by suppressing Wnt signaling.
Synthesis and Prototyping of a 6-dof Parallel Robot for the Automatic Performance of Assembly Tasks (2022)

This paper presents the development of a 6-dof parallel robot for the performance of assembly tasks in a human-robot collaborative environment. The architecture and design of the robot are selected such that the robot is mechanically backdrivable. Thereby, the robot can physically interact with an environment or with humans without requiring the use of a force/torque sensor, which is the main objective of this work. The architecture of the robot is first described and its kinematic model is established. The Jacobian matrices are derived and an algorithm is presented for the determination of its workspace. The force capabilities of the robot are then established based on a proposed formulation. A prototype of the robot is presented and control schemes are developed, including a controller based on a vision system. Finally, a video demonstrating the experimental validation of the robot accompanies this paper. The video qualitatively demonstrates the interaction capabilities of the robot.
Associations of the modified STarT back tool and Hospital Anxiety and Depression Scale (HADS) with gait speed and knee pain in knee osteoarthritis: a retrospective cohort study (2021)

The mSBT had convergent validity with HADS and it showed predictive validity with gait speed and knee pain in knee osteoarthritis. Although broader validation is required, the 5-item mSBT psychosocial measure may be applied as part of routine clinical care to assess psychological distress in patients with knee osteoarthritis.IMPLICATIONS FOR REHABILITATIONThe 5-item psychosocial subscale of the modified STarT Back tool (mSBT) showed good convergent validity with the 14-item Hospital Anxiety and Depression Scale in patients with knee osteoarthritis.The mSBT psychosocial subscale showed predictive validity, at both cross-sectional and longitudinal levels, with gait speed and knee pain in patients with knee osteoarthritis.The mSBT can potentially be used in the busy clinical setting to assess psychological distress in patients with knee osteoarthritis.
Surface-Layer (S-Layer) Proteins Sap and EA1 Govern the Binding of the S-Layer-Associated Protein BslO at the Cell Septa of Bacillus anthracis (2012)

The Gram-positive pathogen Bacillus anthracis contains 24 genes whose products harbor the structurally conserved surface-layer (S-layer) homology (SLH) domain. Proteins endowed with the SLH domain associate with the secondary cell wall polysaccharide (SCWP) following secretion. Two such proteins, Sap and EA1, have the unique ability to self-assemble into a paracrystalline layer on the surface of bacilli and form S layers. Other SLH domain proteins can also be found within the S layer and have been designated Bacillus S-layer-associated protein (BSLs). While both S-layer proteins and BSLs bind the same SCWP, their deposition on the cell surface is not random. For example, BslO is targeted to septal peptidoglycan zones, where it catalyzes the separation of daughter cells. Here we show that an insertional lesion in the sap structural gene results in elongated chains of bacilli, as observed with a bslO mutant. The chain length of the sap mutant can be reduced by the addition of purified BslO in the culture medium. This complementation in trans can be explained by an increased deposition of BslO onto the surface of sap mutant bacilli that extends beyond chain septa. Using fluorescence microscopy, we observed that the Sap S layer does not overlap the EA1 S layer and slowly yields to the EA1 S layer in a growth-phase-dependent manner. Although present all over bacilli, Sap S-layer patches are not observed at septa. Thus, we propose that the dynamic Sap/EA1 S-layer coverage of the envelope restricts the deposition of BslO to the SCWP at septal rings.
Are Odds Really Odd? Bypassing Statistical Detection of Adversarial Examples (2019)

Deep learning classifiers are known to be vulnerable to adversarial examples. A recent paper presented at ICML 2019 proposed a statistical test detection method based on the observation that logits of noisy adversarial examples are biased toward the true class. The method is evaluated on CIFAR-10 dataset and is shown to achieve 99% true positive rate (TPR) at only 1% false positive rate (FPR). In this paper, we first develop a classifier-based adaptation of the statistical test method and show that it improves the detection performance. We then propose Logit Mimicry Attack method to generate adversarial examples such that their logits mimic those of benign images. We show that our attack bypasses both statistical test and classifier-based methods, reducing their TPR to less than 2:2% and 1:6%, respectively, even at 5% FPR. We finally show that a classifier-based detector that is trained with logits of mimicry adversarial examples can be evaded by an adaptive attacker that specifically targets the detector. Furthermore, even a detector that is iteratively trained to defend against adaptive attacker cannot be made robust, indicating that statistics of logits cannot be used to detect adversarial examples.
Birdsnap: Large-Scale Fine-Grained Visual Categorization of Birds (2014)

We address the problem of large-scale fine-grained visual categorization, describing new methods we have used to produce an online field guide to 500 North American bird species. We focus on the challenges raised when such a system is asked to distinguish between highly similar species of birds. First, we introduce "one-vs-most classifiers." By eliminating highly similar species during training, these classifiers achieve more accurate and intuitive results than common one-vs-all classifiers. Second, we show how to estimate spatio-temporal class priors from observations that are sampled at irregular and biased locations. We show how these priors can be used to significantly improve performance. We then show state-of-the-art recognition performance on a new, large dataset that we make publicly available. These recognition methods are integrated into the online field guide, which is also publicly available.
Dense/Porous Asymmetric-Structured Oxygen Permeable Membranes Based on La0.6Ca0.4CoO3Perovskite-Type Oxide (2008)

To achieve high-efficiency oxygen permeation using mixed (ionic and electronic) conducting perovskite-type oxides, we examined asymmetric-structured membranes of La0.6Ca0.4CoO3 in which a thin dense membrane was deposited on a porous support. The La0.6Ca0.4CoO3 porous support was fabricated using irregular-shaped precursor particles prepared through an oxalate method. The fabricated support had good gas permeability and thermal stability, showing sufficient properties as a support for dense thin membranes. A dense membrane of 10 μm thickness was successfully formed on the porous support by coating a La0.6Ca0.4CoO3 slurry and subsequent densification by sintering. The deposited thin membrane was gastight and free from clacks, as revealed by gas permeation tests and SEM observations. The asymmetric membrane exhibited a high oxygen permeability of 1.66 cm3 (STP, standard temperature and pressure) min−1 cm−2 at 930 °C, which was four times higher than that of a typical sintered-disk type membrane with 1200 μm thickness, demonstrating its feasibility as a high-performance oxygen separation membrane.
A simulation model of a wheat elevator system using SLAM (1981)

This paper shows that simulation can be used as an analytical tool for agricultural marketing and the potential of the SLAM simulation language to model such systems. This analysis shows the effects upon the elevator complex from two different harvest season scenarios. The model also has the versatility of being able to derive the effects of different decision strategies on the elevator complex without designing a totally different model. The effects of elevator breakdowns, building of more elevator storage facilities, smaller and larger dumping areas, and different initial elevator inventory levels can be easily investigated. Also, different elevator systems (country, terminal, and export) can be developed from the existing model.
Gadd45a opens up the promoter regions of miR-295 facilitating pluripotency induction (2017)

MicroRNAs (miRNAs) play crucial roles in the establishment of pluripotent state by controlling pluripotent network. However, the molecular mechanisms controlling miRNAs during somatic cell reprogramming remain obscure. In this study, we show Gadd45a (growth arrest and DNA-damage-inducible protein 45a) enhances reprogramming by activating miR-295. Furthermore, we show that Gadd45a binds the promoter regions of miR-295. Nuclease accessibility assay indicates that Gadd45a opens the promoter regions of miR-295. Levels of H3K9Ac and H3K27Ac on the promoter regions of miR-295 were also increased. In conclusion, our results indicate that Gadd45a relaxes the promoter regions of miR-295 and promotes the expression of miR-295 during reprogramming, implying a concise mechanism of Gadd45a and miR-290 cluster cooperation in cell-fate determination.
Fuel Surrogate Physical Property Effects on Direct Injection Spray and Ignition Behavior (2015)

Abstract : Typical hydrocarbon fuels used in internal combustion engines, such as gasoline, diesel, or jet fuel, are composed of hundreds to thousands of hydrocarbon (HC) species. Such a large number of species in high fidelity Computational Fluid Dynamics (CFD) with detailed chemistry is beyond our current computational capability. Therefore, surrogate fuels and their associated chemical mechanisms have been developed and utilized to represent the combustion behavior of typical HC fuels within CFD simulations. The most common surrogate formulation approach seeks to match the combustion related properties of the target fuel. This approach requires reliable models of the HC mixture properties for mathematical optimization, which determines the surrogate composition that minimizes the deviation from the target properties. For modern diesel engines, which employ direct fuel injection, the physical properties of liquid fuel influence the spray, mixture development and ultimately the ignition and combustion process. To more accurately predict the diesel combustion process, it is very important to understand which fuel properties have a major impact on the combustion physics . To date, most studies into the importance of liquid fuel physical properties to combustion behavior have been experimental. While these experiments provided valuable insights, it is difficult to isolate the effect of each property by simply comparing results from different fuels. Computational studies offer a more effective approach to isolate physical fuel property effects from the complex processes occurring during spray combustion. The focus of the current work is on the effect of temperature-dependent physical properties of the liquid fuel (such as density and viscosity) on spray penetration, the evolution of the local thermodynamic states within the jet, and the ignition delay period of compression ignited combustion.