gebhart/patrepeval huggingface dataset:
Liquid crystalline epoxy thermosets based on dihydroxymethylstilbene: Synthesis and characterization (1992)

Abstract This article describes the synthesis and characterization of a new series of liquid crystalline thermosets. Nematic epoxy‐terminated oligoethers based on dihydroxy‐α‐methylstilbene were synthesized for this study. These prepolymers were crosslinked within the nematic mesophase using methylenedianiline. Depending upon the molecular weight and polydispersity of the oligoether, the crosslinking reaction resulted in networks with either a smectic or nematic molecular organization in contrast to the simple nematic phase of the oligoether. The formation of a smectic‐like structure on curing was found to be related to the breadth of the prepolymer molecular weight. In those networks with a low crosslink density a clearing transition could be observed, whereas in the more highly crosslinked networks the molecular organization was frozen in until decomposition. The glass transition temperature of these LC networks rose as the crosslink density was increased, ranging from 35 to 152°C. In agreement with theory, the clearing transition of the networks was found to be dependent on the phase state during curing © 1992 John Wiley &amp; Sons, Inc.
Identification and characterization of a calcium-binding protein in the mouse chorioallantoic placenta (1986)

Mouse chorioallantoic placenta contains a specific calcium-binding protein (MCaBP). A procedure involving gel filtration and ion-exchange chromatography was developed to purify the MCaBP. The MCaBP activity increased as a function of embryonic gestation and was highly specific for Ca2+. The MCaBP is a monomeric protein of Mr 57000, with pI 4.7. Specific antibodies were prepared against the MCaBP and were used to localize the MCaBP to syncytiotrophoblasts of the chorionic villi of mouse chorioallantoic placenta. These properties suggest that the MCaBP may be involved in transplacental calcium transport.
PARALLEL PROCESSING OF MULTIFUNCTIONAL, POINT-OF-CARE BIO-APPLICATIONS ON ELECTROWETTING CHIPS (2010)

We report on performing parallel processing on electrowetting-based digital microfluidic chips by taking advantage of reconfigurable architecture combined with programmable control, scalability, and contamination-free liquid handling. The opportunity is to increase throughput of processes such as sample preparation, biomolecular extraction, and cytotoxicity screening through on-chip resource sharing and without the need for large microfluidic chip I/O.
Myeloprotective Activity of Deoxyspergualin: Influence on Splenic Colony‐forming Cell Injury and Antitumor Activity of Mitomycin C in Mice (1992)

We have examined the efficacy of deoxyspergualin (DSG) in protecting splenic colony-forming cells (CFU-S) from mitomycin C (MMC)-induced damage. The main findings of the study are as follows. (1) When DSG was administered at doses of 1.5 and 3 mg/kg for 7 days before the MMC injection, the decrease of the femoral CFU-S caused by MMC was diminished on the day after the MMC injection. The optimal dose was found to be 3 mg/kg. (2) In animals receiving 3 mg/kg DSG for at least 3 days preceding the MMC injection, the femoral CFU-S was more than 200% of that in the MMC alone group one day after the MMC injection. (3) The number of femoral CFU-S in the mice which received 3 mg/kg DSG for 3 days prior to MMC was significantly restored day by day and reached 70% of normal at 5 days after the MMC injection, while it was only 13% of normal in the MMC alone group. Moreover, the prior DSG administration significantly diminished the MMC toxicity to circulating platelets. (4) DSG administration (3 mg/kg) 3 days prior to MMC did not weaken the antitumor activity against colon 26 adenocarcinoma or P388 leukemia when compared with MMC alone. These findings have shown the ability of DSG specifically to protect the animals against bone marrow toxicity caused by MMC without interfering with the antitumor activity.
Injection seeded Nd:YAG ring laser generating 200 mJ Q-switched pulses (2008)

This paper discusses a novel approach in a seeded Q-switched laser capable in oscillating with no mutual adjustment between cavity resonances and seed emission frequency. The oscillation pulse of such a laser is easy to time-synchronize to external processes. Oscillation of an injection seeded Q-switched Nd:YAG laser module is demonstrated that can laser the pulses from several nsec to about 20 nsec long with the energy level higher than 100 mJ from the slave oscillator and in excess of 200 mJ after a single stage amplification.
Legal Fees: A Comparison of the American and English Rules (1987)

[Introduction] This note is intended to explore some of the issues raised l)y Avery Katz's&#13;\nprovocative paper. The question posed in his paper is whether the English&#13;\nrule or the American rule generates more legal fees. Katz uses game theoretic&#13;\nmotivation for the elasticity measures that are central to his analysis.&#13;\nHowever, the analysis proceeds in terms of elasticity models so the&#13;\nimplications of the underlying game theory remain rather obscure. The approach&#13;\ntaken here is to analyze a game-theoretic model directly to discover&#13;\nwhere the basic principles of the theory lead. The basic approach is similar&#13;\nto other papers and the contribution here is to work out the details of an&#13;\neasy-to-follow example.
Experimental and theoretical investigations of the O(1D) reaction with cyclopropane (2002)

In this report, the O(1D)+c-C3H6 reaction has been investigated using the universal crossed molecular beam technique. Angular resolved time-of-flight spectra have been measured for the observed reaction products in a single set of experiments. Four reaction channels have been observed clearly for this reaction. In addition to the OH+C3H5 channel, the two microchannels for C2H4 formation and the H-atom formation channel are also present. Different product angular distributions were measured for the observed product channels, indicating that each reaction channel occurs with distinctive dynamics. Branching ratios for all observed reaction channels have also been estimated. High-level theoretical calculations have been performed on the energetics of this reaction, indicating two major insertion pathways are likely responsible for most of the reaction channels.
Intrafocal (Kapandji) Pinning of Unstable Distal Radius Fractures (1996)

Seventeen consecutive patients (17 wrists) who underwent intrafocal pinning of unstable distal radius fractures, as described by Kapandji, were retrospectively reviewed at a mean of 42 weeks after surgery (range, 13-88 weeks). The patients were immobilized for 6 weeks postoperatively. All patients were assessed by a single physician and were asked a set of questions regarding subjective and functional status. All patients underwent physical examination of their upper extremities, and bilateral wrist PA and lateral x-rays were taken. There were 13 females and four males; the average age was 49 years. Ten dominant and seven nondominant extremities were involved. Average volar tilt on follow-up lateral wrist radiography was 7 degrees. This compares with -20 degrees at initial presentation, -12 degrees preoperatively, 6 degrees immediately postoperatively, and 10 degrees in the normal wrists. Radial shortening (average) was -2 mm at initial presentation, -1mm preoperatively, 1 mm postoperatively, 0 mm at follow-up, and 1 mm in the normal wrists. Radial inclination was 17 degrees initially, 20 degrees preoperatively, 23 degrees immediately postoperatively, 23 degrees on follow-up, and 24 degrees in the normal wrists. There was a trend for patients with osteopenic bone to lose their postoperative reduction. However, this was not statistically significant. Patients older than 65 years of age had significantly inferior radiologic results. Loss of pronation and supination averaged 2 degrees (range 0-10 degrees) compared with the uninjured wrist. Loss of dorsiflexion averaged 6.5 degrees, and palmar flexion averaged 7.6 degrees. The patients' subjective complaints were minimal. Average pain on visual analog scale (VAS) was 0.44/10. Function measured 8.64/10 (VAS). Sixteen of the patients were happy with the surgery and the outcome of their wrists. Complications included extensor tendon rupture (one patient), pin migration requiring premature removal (one patient), and initial loss of reduction requiring reoperation (one patient). Intrafocal pinning of unstable distal radius fractures provides an effective means to stabilize these complex injuries. Early follow-up suggests that the patients have a satisfactory functional outcome. The complications in this series were preventable. Intrafocal pinning should be added to the surgical armamentarium in treating distal radius fractures.
DIAMONDLIKE CARBON: A BIBLIOGRAPHY OF PUBLISHED PAPERS AND REPORTS. (1985)

A bibliography of references on investigations of diamond-like carbon (DLC) materials is presented. The list was developed over several years of active research and by computerized searches for the following keywords: diamondlike carbon, diamond-like carbon, hard carbon, i-carbon, A-C:H, and amorphous hydrogenated carbon. The bibliography has 241 citations, begins in 1956, includes an author index and was last updated in August 1985.
<title>Parallel processing demonstrator with plug-on-top free-space interconnect optics</title> (2001)

We demonstrate a setup with 10 optically interconnected chips,k which can perform a distributed radix-2-butterfly calculation for fast Fourier transformation. The setup consists of a motherboard, five multi-chip-modules (MCMs, with processor/transceiver chips and laser/detector chips), four plug-on-top optics modules that provide the bi- directional optical links between the MCMs, and external control electronics. The design of the optics and optomechanics satisfies numerous real-world constraints, such as compact size (&lt; 1 inch thick), suitability for mass-production, suitability for large arrays (up to 10<SUP>3</SUP> parallel channels), compatibility with standard electronics fabrication and packaging technology, and potential for active misalignment compensation by integrating MEMS technology.
GaN laser diodes for quantum sensing (2020)

Quantum technologies containing key GaN laser components will enable a new generation of precision sensors, optical atomic clocks and secure communication systems for many applications such as next generation navigation, gravity mapping and timing since the AlGaInN material system allows for laser diodes to be fabricated over a wide range of wavelengths from the u.v. to the visible. We report our latest results on a range of AlGaInN diode-lasers targeted to meet the linewidth, wavelength and power requirements suitable for quantum sensors such as optical clocks and cold-atom interferometry systems. This includes the [5s<sup>2</sup>S<sub>1/2</sub>-5p<sup>2</sup>P<sub>1/2</sub>] cooling transition in strontium+ ion optical clocks at 422 nm, the [5s<sup>2</sup> <sup>1</sup>S<sub>0</sub>-5p<sup>1</sup>P<sub>1</sub>] cooling transition in neutral strontium clocks at 461 nm and the [5s<sup>2</sup>s<sub>1/2</sub> – 6p<sup>2</sup>P<sub>3/2</sub>] transition in rubidium at 420 nm. Several approaches are taken to achieve the required linewidth, wavelength and power, including an extended cavity laser diode (ECLD) system and an on-chip grating, distributed feedback (DFB) GaN laser diode.
A New Mechanism for Excitation of Waves in a Magnetoplasma: I. Linear Theory (2011)

We suggest a new mechanism for exciting waves in a magnetoplasma containing a transverse component of a nonuniform electric field. The energy density of the waves can become negative in the region where the transverse electric field is localized while it is positive outside this region. The coupling of the two adjoining regions through a nonlocal wavepacket allows a flow of energy from the negative energy region towards the positive energy region. This enables the mode to grow. We use ion cyclotron waves as an example to display the subtler features of the mechanism.
Erratum: Optimal packings of superballs [Phys. Rev. E79, 041309 (2009)] (2011)

Received 4 December 2011DOI:https://doi.org/10.1103/PhysRevE.84.069902©2011 American Physical Society
Large‐scale eigenvalue calculations for stability analysis of steady flows on massively parallel computers (2001)

We present an approach for determining the linear stability of steady states of PDEs on massively parallel computers.Linearizing the transient behavior around a steady state leads to a generalized eigenvalue problem.The eigenvalues with largest real part are calculated using Arnoldi's iteration driven by a novel implementation of the Cayley transformation to recast the problem as an ordinary eigenvalue problem.The Cayley transformation requires the solution of a linear system at each Arnoldl iteration, which must be done iteratively for the algorithm to scale with problem size.A representative model problem of 3D incompressible flow and heat transfer in a rotating disk reactor is used to analyze the effect of algorithmic parameters on the performance of the eigenvalue algorithm.Successful calculations of leading eigenvalues for matrix systems of order up to 4 million were performed, identi&ing the critical Grashof number for a Hopf bifurcation.
Heme Oxygenase-1 (HO-1)/Heat Shock Protein 32 (Hsp32) as a Novel Survival Factor and Target in AML. (2006)

Abstract Heme oxygenase 1 (HO-1), also known as heat shock protein 32 (Hsp32), has recently been identified as a stress-related survival molecule that acts anti-apoptotic and cytoprotective in inflammatory reactions. Recent data suggest that HO-1/Hsp32 is also expressed in neoplastic cells in various malignancies. In the present study, we provide evidence that HO-1 is constitutively expressed in primary leukemic cells in patients with acute myeloid leukemia (AML, n=17) and in various AML cell lines such as HL60, KG1, KG1a, and U937. Expression of HO-1 mRNA was demonstrable by RT-PCR, and the HO-1 protein by immunocytochemistry and Western blotting. In addition, we were able to demonstrate expression of HO-1 mRNA and of HO-1 protein in the CD34+/CD38− progenitor/stem cell fraction in the leukemic clone in patients with AML. The HO-1 inductor hemin (10 μM) was found to promote expression of HO-1 in AML cells. Incubation with the HO-1-targeting drugs pegylated zink protoporphyrin (PEG-ZnPP) or styrene maleic acid-conjugated ZnPP (SMA-ZnPP), resulted in a dose-dependent inhibition of growth of leukemic cells at pharmacologic concentrations (IC50: 5–20 μM for cell lines and primary AML cells). The SMA-ZnPP-induced growth-inhibition of AML cells were found to be associated with induction of apoptosis as evidenced by light microscopy, electron microscopy, and by a Tunel assay. In consecutive experiments, combination experiments were performed using SMA-ZnPP and AML cell lines. In these experiments, SMA-ZnPP was found to synergize with cytarabine in producing growth inhibition in all AML cell lines tested. In summary, these data show that HO-1/Hsp32 is a novel survival factor and interesting target in AML. The clinical significance of this observation remains to be determined in forthcoming trials.
Robust Statistical Processing Of Tdoa Estimates For Distant Speaker Diarization (2018)

Publication in the conference proceedings of EUSIPCO, Kos island, Greece, 2017
The Effect of Westernization on Native Populations. Studies on a Micronesian Community with a High Diabetes Prevalence (1978)

A diabetes prevalence study in 1975 on an isolated urbanized Central Pacific island (Nauru) showed rates comparable to the American Pima Indians--the highest yet recorded in the world literature. This paper reports the results of a follow-up study and the high prevalence has been confirmed. In this survey of 417 people aged ten years and over, 9.8% were known diabetics. With a plasma glucose of 160 mg/100 ml or over at two hours after a 75 gram oral glucose load as the criterion of diagnosis, , diabetes was detected in a further 19.2%, making a total diabetic population of 29% in the population studied. The prevalence of diabetes was 44% in people aged 20 years and over. A further 7% had borderline diabetes on the basis of a two-hour plasma glucose of 140--159 mg/100 ml. Parity did not appear to be a causative factor in relation to the high diabetes prevalence. However, obesity is common in this community and is more marked than that seen in other Pacific or Caucasian communities. The high prevalence of diabetes in this population appears to be related to the inter-action of environmental factors, such as obesity, with a diabetic genotype. The results confirm the possible detrimental effects of westernization on native populations.
Elimination of Schistosoma mansoni in infected mice by slow release of artemisone (2017)

The current treatment of schistosomiasis is based on the anti-helminthic drug praziquantel (PZQ). PZQ affects only the adult stages of schistosomes. In addition, resistance to PZQ is emerging. We suggest a drug, which could serve as a potential alternative or complement to PZQ, and as a means of treating infections at earlier, pre-granuloma stage. Derivatives of the peroxidic antimalarial drug artemisinin have been indicated as alternatives, because both plasmodia and schistosomes are blood-feeding parasites. The mechanism of action of artemisinins is related to oxidative effects of the artemisinins on intracellular reductants leading to formation of cytotoxic reactive oxygen species. We used artemisone, which has improved pharmacokinetics and anti-plasmodial activity, and reduced toxicity compared to other artemisinins in clinical use against malaria. We infected adult mice by subcutaneous injection of S. mansoni cercariae (about 200) and treated them at various times post infection by the following methods: i. artemisone suspension administered by gavage (400-450 mg/kg); ii. subcutaneous injection of a gel containing a known concentration of artemisone (115-120 mg/kg); iii. subcutaneous insertion of the drug incorporated in a solid polymer (56-60 mg/kg); iv. intraperitoneal injection of the drug solubilized in DMSO (115-120 mg/kg). Drug administration in polymers was performed to enable slow release of the artemisone that was verified in vivo and in vitro bioassays using drug-sensitive malaria parasites. We found superior strong anti-schistosome effects up to a total reduction of worm number, mainly following repetitive treatments with the drug absorbed in the polymers (73.1% and 95.9% reduction in mice treated with artemisone in gel 7 and 14, and 21, 28 and 35 days post infection, respectively). The results indicate that artemisone has a potent anti-schistosome activity. Its main importance in this context is its effectiveness in treating hosts harboring juvenile schistosomes, before egg-deposition and induction of deleterious immune responses.
Review on recent progress in patterning phase change materials (2020)

This review discusses critical aspects of patterning phase change materials (PCMs), including dry etching, wet clean, and encapsulation, as they dictate the reliability and functionality of the phase change random access memory devices. Specifically, alloys of germanium–antimony–tellurium are used as a model system, and the importance of PCM composition control, critical dimension control, high fidelity pattern transfer, and a system level of ambient control to avoid oxidation that can alter the materials’ functionality are highlighted. The research findings motivate the development of a state-of-the-art integrated system that combines dry etch, wet clean, and encapsulation into one platform to realize consistent and successful patterning of PCMs for future generations of the memory devices.
MT1-MMP Is Required for Hematopoietic Maturation in the BM Niche. (2009)

Abstract Abstract 3634 Poster Board III-570 Specialized niches, in which hematopoietic stem cells (HSCs) reside control the balance between HSC quiescence and self-renewal, yet little is known about the extrinsic signals provided by the niche and how these niche signals regulate such a balance. Activation of the fibrinolytic pathway via matrix metalloproteinase-9 (MMP-9) resulted in the release of kit ligand (KitL) in the BM niche. Membrane type 1-MMP (MT1-MMP) can activate e.g. MMP-9. To investigate the role of MT1-MMP in hematopoiesis, we used MT1-MMP deficient mice. MT1-MMP−/− mice examined 12 days after birth showed pancytopenia and reduced numbers of bone marrow mononuclear cells (BMMCs) and splenocytes. BM cytospins from MT1-MMP−/− mice showed mild perturbations in erythropoiesis and a more severe impairment of myelopoiesis. Although all lineages were present, the ratio of erythroid to myeloid precursors increased from 0.36 in wildtype to 0.60 in MT1-MMP−/− mice. Myeloid and erythroid cell differentiation was impaired in MT1-MMP−/− BMMCs. The numbers of colony forming unit cells (CFU-C) was reduced in MT1-MMP−/− BMMCs. In contrary, the number of immature hematopoietic cells (CFU-S8, KSL cells) was augmented in MT1-MMP−/− BMMCs. FACS analysis of BM cells showed a decrease in the percentage of mature B cells with an increase number of Pro-B and immature B cells in MT1-MMP−/− BMMCs relative to controls. MT1-MMP−/− BM cells showed lower expression of CXCL12 and KitL, typical niche growth factors important for myelopoiesis and lymphopoisis. Thus, MT1-MMP is required for normal hematopoietic differentiation of lymphoid and myeloid lineage cells, most likely due to growth factor defective niche cells. Disclosures: No relevant conflicts of interest to declare.
Autosomal Dominant Microcephaly Associated With Congenital Lymphedema and Chorioretinopathy Due to a Novel Mutation inKIF11 (2015)

Our website uses cookies to enhance your experience. By continuing to use our site, or clicking "Continue," you are agreeing to our Cookie Policy | Continue JAMA Ophthalmology HomeNew OnlineCurrent IssueFor Authors Podcast Publications JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry (1919-1959) JN Learning / CMESubscribeJobsInstitutions / LibrariansReprints & Permissions Terms of Use | Privacy Policy | Accessibility Statement 2023 American Medical Association. All Rights Reserved Search All JAMA JAMA Network Open JAMA Cardiology JAMA Dermatology JAMA Forum Archive JAMA Health Forum JAMA Internal Medicine JAMA Neurology JAMA Oncology JAMA Ophthalmology JAMA Otolaryngology–Head & Neck Surgery JAMA Pediatrics JAMA Psychiatry JAMA Surgery Archives of Neurology & Psychiatry Input Search Term Sign In Individual Sign In Sign inCreate an Account Access through your institution Sign In Purchase Options: Buy this article Rent this article Subscribe to the JAMA Ophthalmology journal
Therapeutic Effect of Ribbon-Type Nuclear Factor-&kappa;B Decoy Oligonucleotides in a Rat Model of Inflammatory Bowel Disease (2012)

These data suggest that intracolonic administration of R-ODN may be effective to treat DSS-induced colitis.
New instrumentation technologies for testing the bonding of sensors to solid materials (1996)

This report presents the results of a comprehensive research and development project that was conducted over a three-year period to develop new technologies for testing the attachment of sensors to solid materials for the following NASA applications: (1) testing the performance of composites that are used for the lining of solid rocket motor nozzles, (2) testing the bonding of surface-mounted platinum resistance thermometers that are used on fuel and oxidizer lines of the space shuttle to detect valve leaks by monitoring temperature, (3) testing the attachment of strain gages that are used in testing the performance of space shuttle main engines, and (4) testing the thermocouples that are used for determining the performance of blast tube liner material in solid rocket boosters.