gebhart/patrepeval huggingface dataset:
Zeolite host-guest interactions: optical spectroscopic properties of tris(bipyridine)ruthenium(II) in zeolite Y cages (1990)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTZeolite host-guest interactions: optical spectroscopic properties of tris(bipyridine)ruthenium(II) in zeolite Y cagesJoseph A. Incavo and Prabir K. DuttaCite this: J. Phys. Chem. 1990, 94, 7, 3075–3081Publication Date (Print):April 5, 1990Publication History Published online1 May 2002Published inissue 5 April 1990https://doi.org/10.1021/j100370a061RIGHTS & PERMISSIONSArticle Views469Altmetric-Citations89LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (896 KB) Get e-Alerts
Behaviors of QFN Packages on a Leadframe Strip (2016)

Abstract To lower the manufacturing cost of quad flat no-lead (QFN) packages, the number of QFN packages on a leadframe must be increased. However, the increased number of packages or changes to the layout of QFN packages on the leadframe can impact the mold compound flow behavior, which will, in turn, affect warpage, and the generation of voids inside the mold compound. In this paper, both simulation and experimental approaches were conducted to study the behaviors of QFN packages on a leadframe strip. For simulation, we will demonstrate and present an analysis methodology to account for the in-line processing parameters, especially the step of manufacturing and processing the mold compound material to form the QFN packages on a leadframe strip. The in-line manufacturing parameters, such as pressure, temperature, shrinkage, and processing timing, were all considered and modeled. A commercial finite element tool was used. For the experiment, we measured the warpages and the voids of QFN packages as a function of the package location on the leadframe. The warpage of the package, and the voids generation of QFN packages at different locations on the leadframe strip were studied. In conclusion, the experiment vs. modeling data was correlated, and the study proved to be very useful for the prediction of warpage, and void generations.
High-rate WPAN (2007)

With the adoption of the 3.1-10.6 GHz band by the Federal Communications Commission (FCC) for commercial wireless communication, Ultra Wide-Band (UWB) has attracted both scientific and commercial interest and is now emerging as a promising technology for high-speed (several hundred Mbps and beyond)) short-range wireless communications for home and office networking applications. Sometimes also referred to as impulse radio, UWB communication systems operate across a wide range of spectrum relative to the center frequency. The radiated energy, occupying a large bandwidth (typically measured in GHz), is often made sufficiently small that it can facilitate co-existence with other devices without causing significant harmful interference to them. Advantages of current UWB implementations include low-cost, low-power, and resilience to multi-path interference.
ChemInform Abstract: Concise Construction of Novel Bridged Bicyclic Lactams by Sequenced Ugi/RCM/Heck Reactions. (2008)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Lead-free soldering process for coil terminals by using atmospheric pressure plasma technique (2004)

Recently, much attention is paid to the environmental problems caused by lead”, and practical use of lead-free solder is especially accelerated in the field of printed writing boards. However, lead solder commonly used for terminals of coils hasn’t yet replaced by lead-free solder. From solder-plated terminals, lead flows into the lead-free solder bath during wave soldering process, so we are faced with a problem of lead concentration in a solder bath. Conventionally, it is possible to plate coil terminals with lead solder by dipping it into the solder bath, but such a procedure cannot be applied to lead-free solder. So the process of removing insulator film coated on a copper wire and plating the treated copper wire with lead-free solder is strongly required.
Polymer Solar Cells: Efficient Small Bandgap Polymer Solar Cells with High Fill Factors for 300 nm Thick Films (Adv. Mater. 23/2013) (2013)

The morphology of a new high molecular weight push-pull semiconducting donor polymer provides a semi-crystalline fibrous network of polymers chains when blended with a fullerene acceptor. This organized morphology enables reaching high fill factors and power conversion efficiencies in organic solar cell for films up to 300 nm thickness, as reported by René A. J. Janssen and co-workers on page 3182. Image: ICMS Animation Studio, TU/e.
Inhibitor binding to the Phe53Trp mutant of HIV-1 protease promotes conformational changes detectable by spectrofluorometry (1993)

HIV-1 protease contains two identical, conformationally mobile loops, known as flaps, which form in part the binding pockets for substrates and inhibitors. We have constructed a site-specific mutant of the protease in which residues Phe-53 and Phe-153 at the end of the flaps have been mutated to Trp residues, in order to incorporate a specific fluorescent probe to monitor conformational changes upon the binding of an inhibitor. The Phe53Trp (F53W) mutant of HIV-1 protease was expressed in Escherichia coli and purified from bacterial lysates. Analysis of the purified mutant protease demonstrated that its kinetic properties were highly similar to those of the wild-type protease. While binding of a potent peptide-analogue inhibitor (Ki = 9 nM) to the wild-type enzyme led to no change in protein fluorescence, a 5-8% increase in fluorescence was observed with the F53W mutant, indicating an enhancement of the Trp fluorescence due to flap movement upon inhibitor binding. Investigation of the kinetics of the F53W protease-inhibitor binding by stopped-flow spectrofluorometry revealed a rapid increase in protein fluorescence upon formation of the enzyme-inhibitor complex. These data were consistent with a one-step mechanistic model of inhibitor binding in which flap movement was concomitant with inhibitor binding, from which respective rate constants of association and dissociation of 2.5 x 10(6) M-1 s-1 and 0.023 s-1 were obtained.
Boosting cross-modality image registration (2009)

Cross-modality image registration is a difficult problem because the same structures have different intensity patterns in the two modalities, making straightforward methods based on SSD or cross-correlation not applicable. This paper presents a learning based approach to cross-modality image registration. First, it describes a method to map the image registration problem into a problem of binary classification. Then, it presents a method to select a number of image registration algorithms from a larger pool and combine them by AdaBoost into a boosted algorithm that is more accurate than any of the algorithms in the pool. Finally, it presents a method named virtual boosting that allows to directly obtain the result of the boosted algorithm without performing any parameter search. In our cross-modality image registration application, the algorithm pool consists of many feature-based registration algorithms with different configurations. An experimental validation on the registration of thousands of aerial video frames with satellite images from Google Maps showed that the boosted algorithm has a 20-30% smaller error than the best registration algorithm from the pool (based on SIFT features). More generally, the method presented can be applied to combine a number of algorithms aimed at solving the same problem into a boosted algorithm that is more accurate than any of them.
The Role of Brain-Reactive Autoantibodies in Brain Pathology and Cognitive Impairment (2017)

Antibodies to different brain proteins have been recently found to be associated with an increasing number of different autoimmune diseases. They need to penetrate the blood-brain barrier (BBB) in order to bind antigens within the central nervous system (CNS). They can target either neuronal or non-neuronal antigen and result in damage either by themselves or in synergy with other inflammatory mediators. Antibodies can lead to acute brain pathology, which may be reversible; alternatively, they may trigger irreversible damage that persists even though the antibodies are no longer present. In this review, we will describe two different autoimmune conditions and the role of their antibodies in causing brain pathology. In systemic lupus erythematosus (SLE), patients can have double stranded DNA antibodies that cross react with the neuronal <i>N</i>-methyl-d-aspartate receptor (NMDAR), which have been recently linked to neurocognitive dysfunction. In neuromyelitis optica (NMO), antibodies to astrocytic aquaporin-4 (AQP4) are diagnostic of disease. There is emerging evidence that pathogenic T cells also play an important role for the disease pathogenesis in NMO since they infiltrate in the CNS. In order to enable appropriate and less invasive treatment for antibody-mediated diseases, we need to understand the mechanisms of antibody-mediated pathology, the acute and chronic effects of antibody exposure, if the antibodies are produced intrathecally or systemically, their target antigen, and what triggers their production. Emerging data also show that <i>in utero</i> exposure to some brain-reactive antibodies, such as those found in SLE, can cause neurodevelopmental impairment since they can penetrate the embryonic BBB. If the antibody exposure occurs at a critical time of development, this can result in irreversible damage of the offspring that persists throughout adulthood.
Comparison of Dual and Thermal Gradient Recording Methods for Thermally Assisted Magnetic Recording (2009)

The comparison between the dual gradient recording method (DGRM) and the thermal gradient recording method (TGRM) for thermally assisted magnetic recording (TAR) were investigated using the Landau-Lifshitz-Gilbert equation, which adds a stochastic thermal field to an effective field. The magnetization patterns and read/write characteristics were discussed. It was clarified that the write performance of DGRM was superior to TGRM for achieving a high areal recording density.
Morphology of Model Graft Copolymers with Randomly Placed Trifunctional and Tetrafunctional Branch Points (1998)

The morphologies of two series of model graft copolymers were studied using transmission electron microscopy (TEM) and small-angle X-ray scattering (SAXS). Both series of materials have monodisperse polybutadiene (PB) backbones and monodisperse polystyrene (PS) graft blocks. In one series there are on average five trifunctional junction points randomly distributed along the PB backbone. Each junction point grafts one PS block to the backbone. In the other series there are on average four tetrafunctional junction points randomly distributed along the PB backbone. Each junction point grafts two PS blocks to the backbone. A range of overall PB and PS volume fractions was investigated for both series. These materials simulate a controlled and known degree of architectural disorder. Current theory cannot rigorously predict the morphological behavior for these complex molecular architectures. However, it is found that an approximate extension of existing theory utilizing the constituting block copolymer (fundamental building block) concept allows a rational explanation of the effect of architecture on morphology in these materials. The materials form the domain shape (spheres, cylinders, or lamellae) which is predicted by theory, but spherical and cylindrical morphologies lack the long-range lattice order found in diblocks and other simpler block copolymer molecular architectures. When lamellar morphologies are formed, however, at least some long range order is always present due to the space filling requirements of the lamellar domains.
Supplementary Figure Legend and Tables 1 - 4 from CpG Island Methylator Phenotype–Positive Tumors in the Absence of <i>MLH1</i> Methylation Constitute a Distinct Subset of Duodenal Adenocarcinomas and Are Associated with Poor Prognosis (2023)

&lt;p&gt;PDF file, 113K, Supplementary Figure Legend; Supplementary Table S1. List of primers used for methylation-specific PCR; S 2. List of KRAS mutations in patients with duodenal Adenocarcinomas; S3. Five year and 10 year cumulative proportion of overall survival and time-to-recurrence for different molecular groups; S4. Univariate and multivariate Cox proportional hazard analysis of overall survival and time-to-recurrence for CIMP, MLH1 methylation or MSI status.&lt;/p&gt;
A Scalable Synthesis of an Atropisomeric Drug Substance via Buchwald–Hartwig Amination and Bruylants Reactions (2013)

A practical, chromatography-free synthesis for a chemokine receptor antagonist NIBR-1282 (1) is described. Highlights of this scalable synthesis include (1) Buchwald–Hartwig amination reaction using (t-Bu)3P as the ligand and 5–12 mol % of water as an additive affording 6 with yield increase of more than 2-fold; (2) a variant of the Bruylants reaction for the synthesis of α-methyl amine 10 via aminotriazole 15a, instead of classical amino nitrile 8; and (3) development of a crystallization-induced, atropisomer transformation leading to predominantly one atropisomer 1. The new approach was employed for the manufacturing of kilogram quantities of the target active pharmaceutical ingredient.
Polyvalent DNA prime and envelope protein boost HIV‐1 vaccine elicits humoral and cellular responses and controls plasma viremia in rhesus macaques following rectal challenge with an R5 SHIV isolate (2005)

Immunization of macaques with multivalent DNA encoding gp120 genes from HIV-1 subtypes A, B, C and E and a gag gene followed by boosting with homologous gp120 proteins elicited strong anti-gp120 antibodies capable of neutralizing homologous and to a lesser degree heterologous HIV-1 isolates. Both Env- and Gag-specific cell mediated immune (CMI) responses were detected in the immunized animals. Following rectal challenge with an SHIV isolate encoding HIV-1(Ba-L)env, plasma viremia in the infected immunized animals was significantly lower than that observed in the naïve animals. Further, one of six immunized animals was completely protected whereas all six naïve animals were infected. These results demonstrate that a vaccine based on priming with a polyvalent DNA vaccine from multiple HIV-1 subtypes followed by boosting with homologous Env proteins elicits anti-HIV-1 immune responses capable of controlling rectal transmission of SHIV(Ba-L).
44‐2: In‐cell Touch Panel LCD Driving Method for EMI Mitigation for Automotive Application (2021)

Automotive applications require suppressing EMI (Electro Magnetic Interference) noise in order to avoid interference with other electrical components, and the specification is much tighter than mobile applications. Currently, in‐cell touch LCDs are widely seen in the market especially in mobile phone applications, which are integrating touch panel function in the display due to the simple structure of in‐cell touch LCDs. However, in‐cell touch LCDs generally emit higher EMI noise than LCDs with discrete touch panels, since the LCD surface area cannot be covered by electrical shield layer with in‐cell touch architecture while it can be in a discrete touch panel. Therefore, EMI is a critical issue when using in‐cell touch LCDs for automotive applications. For this paper we introduce driving techniques for in‐cell touch LCD which mitigate EMI for automotive applications in order to pass the criteria of automotive application without deterioration of picture image quality.
ChemInform Abstract: Conformational Analysis of Thiophene Analogues of Propranolol (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
New atrial arrhythmia occurrence in single chamber implantable cardioverter defibrillator patients: A real‐world investigation (2022)

Continuous AF monitoring with the new VBAF algorithm permits early identification and actionable treatment for patients with undiagnosed AF that may improve patient outcomes.
Thermodynamically Consistent Model for Space-Charge-Layer Formation in a Solid Electrolyte (2015)

We derive a mathematical model for space-charge-layer formation in a solid electrolyte based on first principles only. Consistent with the second law of thermodynamics, we employ mass, momentum, and energy conservation, supplemented with constitutive assumptions in the form of a Helmholtz free-energy functional. The resulting system of differential equations is solved semianalytically for a stationary 1D case, and the parametric dependencies of the space-charge layers forming at the boundaries under the influence of an external voltage are studied. We present results for different applied potentials, dielectric susceptibilities, and other parameters and compare our results with experiments. The predicted space-charge layers at the boundaries are in general not symmetric due to the restricted mobility of the anion lattice. Their size is found to be approximately 1 order of magnitude larger compared with liquid electrolytes, even if all macroscopic properties like mass density, dielectric constant, etc. are the same. Depending strongly on the dielectric properties of the material, typical widths of space-charge layers in some glass ceramics with very high dielectric susceptibility are predicted to be as large as several hundreds of nanometers, in qualitative agreement with experimental results in literature.
Lipocalin-2 Acts as a Neuroinflammatogen in Lipopolysaccharide-injected Mice (2014)

Lipocalin-2 (LCN2) is a key mediator of various cellular processes. Recent studies have indicated that LCN2 also plays an important role in central nervous system (CNS) injuries and neurological diseases, such as spinal cord injury, stroke, experimental autoimmune encephalomyelitis, and neurodegenerative diseases. Here, we investigated the role of LCN2 in a rodent model of lipopolysaccharide (LPS)-induced neuroinflammation. At 24 hours after intraperitoneal injection of LPS, LCN2 expression was strongly induced in the brain; LCN2 was mainly expressed in endothelial cells, astrocytes, and microglia. Next, we used LCN2-deficient mice to further investigate the role of LCN2 in neuroinflammation. LCN2 deficiency attenuated LPS-induced glial activation in the brain. In a mechanistic study employing glia/neuron co-cultures, LCN2 deficiency reduced glial neurotoxicity. Our results indicate that LCN2 plays a central role in the neuroinflammatory responses following LPS administration, and that LCN2 might contribute to the uncontrolled neurotoxic glial activation under excessive and chronic inflammatory conditions.
Distant organ dysfunction in acute kidney injury (2019)

Acute kidney injury (AKI) is a common complication in critically ill patients and it is associated with increased morbidity and mortality. Epidemiological and clinical data show that AKI is linked to a wide range of distant organ injuries, with the lungs, heart, liver, and intestines representing the most clinically relevant affected organs. This distant organ injury during AKI predisposes patients to progression to multiple organ dysfunction syndrome and ultimately, death. The strongest direct evidence of distant organ injury occurring in AKI has been obtained from animal models. The identified mechanisms include systemic inflammatory changes, oxidative stress, increases in leucocyte trafficking and the activation of proapoptotic pathways. Understanding the pathways driving AKI-induced distal organ injury are critical for the development and refinement of therapies for the prevention and attenuation of AKI-related morbidity and mortality. The purpose of this review is to summarize both clinical and preclinical studies of AKI and its role in distant organ injury.
Motion-compensated targeting in pulmonary interventions using cone-beam CT and locally rigid / globally deformable 3D-2D registration (2022)

Purpose. Mobile C-arms capable of 2D fluoroscopy and 3D cone-beam CT (CBCT) are finding application in guidance of transbronchial lung biopsy, but unresolved deformable motion presents challenges to accurate target localization and guidance. We report the initial implementation of a method to resolve deformations via locally rigid / globally deformable 3D-2D registration for motion-compensated overlay of planning data in fluoroscopically-guided pulmonary interventions. Methods. The algorithm proceeds in 3 steps: (1) initialization by 3D-2D rigid registration of CBCT to fluoroscopy (driven by bone gradients); (2) local rigid 3D-2D registration of lung-thresholded CBCT to fluoroscopy within a region of interest (ROI) about each target location; and (3) aggregation of local rigid registrations to estimate global deformation. Several objective functions and optimizers were evaluated for soft-tissue target registration. Phantom studies were performed to determine operating parameters and assess performance with simulated lung deformation. Results. Soft-tissue thresholding and contrast enhancement improved target registration error (TRE) from 10.3 mm for conventional 3D-2D registration (driven primarily by rib gradients) to 3.8 mm using locally rigid 3D-2D registration in regions of interest about each target. The soft-tissue gradient orientation (GO) objective function was found to be superior to alternative similarity measures by de-emphasizing gradient magnitude (in favor of gradient orientation), permitting the algorithm to be better driven by soft-tissue edges. Conclusions. Registration driven by soft-tissue targets is achievable via a novel processing framework to de-emphasize non-target gradients. The proposed method could improve the accuracy of guidance in pulmonary interventions by updating target overlay in fluoroscopy.
Genome-wide detection of segmental duplications and potential assembly errors in the human genome sequence (2003)

Using two distinct computational approaches, we have identified most of the sequences in the human genome that have undergone recent segmental duplications. Near-identical segmental duplications present a major challenge to the completion of the human genome sequence. Potential sequence misassignments detected in this study would require additional efforts to resolve.
Card Body for Smart Cards (2002)

In Chapter Two, a brief history of the development of the smart card is provided. The focus of this chapter is an overview of card body materials. The advantages and disadvantages of the use of key materials are discussed, material properties are outlined and the impact of the thickness of the plastic foils is also covered. Smart card elements such as the magnetic stripe, printing methods and signature panels are described.