gebhart/patrepeval huggingface dataset:
Deep Brain Stimulation for Patients With Dystonia (2006)

Dr. Lee is Assistant Professor, Department of Neurosurgery, University of Pennsylvania, 330 S. 9th Street, 4th Floor, Philadelphia, PA 19107, E-mail: [email protected]; Dr. Deogaonkar is Fellow, Center for Neurological Restoration, Cleveland Clinic Foundation; and Dr. Rezai is Co-Chairman, Center for Neurological Restoration, Cleveland Clinic Foundation, Cleveland, OH. Dr. Rezai has disclosed that he is/was the recipient of a research grant from Medtronic Neurosurgical. Drs. Deogaonkar and Lee have disclosed that they have no significant relationships with or financial interests in any commercial organization related to this educational activity. Lippincott CME Institute, Inc., has identified and resolved all faculty conflicts of interest regarding this educational activity. Category: Functional
Highly performing wavelength converter based on dual pump wave mixing in semiconductor optical amplifier (1998)

The dual pump four wave mixing (FWM) in semiconductor optical amplifiers (SOAs) has been proposed as a promising method to achieve high efficiency and signal to background noise ratio (SBR), specially for large wavelength shifts. In the present work experimental study and theoretical modeling of the mixing processes generating the converted signal will be presented. Moreover, the operation of the dual pump converter in a 10 Gb/s experiment will be demonstrated.
Tissues of the Laron Dwarf Are Sensitive to Insulin-Like Growth Factor I But Not to Growth Hormone* (1987)

Tissues from patients with Laron dwarfism are resistant to the actions of endogenous or exogenous GH. As a result, insulin-like growth factor I (IGF-I) levels are low, possibly contributing to the severe growth deficiency that occurs in patients with this syndrome. In this study, we found that erythroid progenitor cells and permanently transformed T-cell lines from two patients with Laron dwarfism responded in vitro to added IGF-I in concentrations ranging between 1-10 ng/mL despite no stimulatory response to added GH in concentrations of up to 500 ng/mL. Normal or near-normal responsiveness to insulin was also demonstrated. The persistence of GH resistance in the cultured T-cell lines confirms the primary genetic nature of the defect in Laron dwarfism. The preservation of in vitro growth responsiveness to IGF-I in hematopoietic tissue from the Laron dwarfs suggests that affected individuals are sensitive to this factor and may respond to it in vivo.
Mixed phase Ge2Sb2Te5 thin films with temperature independent resistivity (2013)

The electrical properties of polycrystalline Ge2Sb2Te5 thin films containing both the metastable fcc phase and the stable hcp phase have been studied. The resistivity and its temperature dependence have been modelled using effective medium approximation. By varying the volume fraction of the two phases it is possible to get films with different resistivities and temperature coefficient of resistance, changing without discontinuity from negative (fcc) to positive value (hcp). Mixed phase films with resistivity almost independent of the temperature are obtained at about 4 mΩ cm.
Fabrication and measurement of wideband achromatic waveplates for the mid-infrared region using subwavelength features (2006)

Subwavelength diffractive features etched into a substrate lead to form birefringence that can produce polarization sensitive elements such as wave plates. Using etched features allows for the development of pixelated devices to be used in conjunction with focal plane arrays in polarimetric imaging systems. Form birefringence exhibits dispersion that can be advantageous to the design of wave plates with an achromatic response. Taking advantage of this dispersion, diffractive wave plates with good achromatic characteristics can be designed for the 2- to 5-µm spectral region. Previous work in this area has produced good results over a subset of this wavelength band, but designing for this extended band is particularly challenging. The fabrication processes for the subwavelength features will be discussed and fabricated devices with a measured average phase retardation of 80.6 deg and rms variation of 9.41 deg will be presented.
3D Camera Pose History Visualization (2016)

We present a 3D camera pose history visualization that can assist users of CAD software's, virtual worlds and scientific visualizations to revisit their navigation history. The contribution of this system is to enable users to move more efficiently through the virtual environment so they can focus on their main activity.
Beam Scanning Using Flat Transformation Electromagnetic Focusing Lenses (2009)

A beam scanning/switching method utilizing a transformation electromagnetics device is presented. A flat focusing lens based on the coordinate transformation approach is designed such that the field radiated by an antenna at the lens focus is transformed into a directive beam emitted normal to the lens surface. The main beam can be scanned by moving the antenna in the focal plane. Physical movement of the source or the lens can be avoided by placing an array of radiators in the focal plane. Selective excitations of individual antennas in a linear array configuration result in switched beams. Full-wave numerical simulations are performed, and the results for 2D lens configurations with line sources are provided.
S2458 Rosacea Improved Following Treatment With Combination Antibiotics and Fecal Microbiota Transplantation: Two Case Reports (2022)

Introduction: Rosacea is a chronic skin condition affecting nearly 18% of the population worldwide. It is characterised by flushing or redness of the cheeks, nose, chin and/or forehead. In severe cases visible blood vessels, inflammatory acne or skin thickening may be present. The cause of rosacea remains unknown and treatments are limited. Emerging evidence suggests a link between gastrointestinal (GI) microbiome dysbiosis and rosacea. Here, we report 2 cases who received fecal microbiota transplantation (FMT) for irritable bowel syndrome (IBS) and reported an improvement in concomitant rosacea. Case Description/Methods: Case 1: A female (65yrs) presented with known IBS characterised by bloating, abdominal pain and diarrhoea. Medical history included subtotal hysterectomy and optical rosacea, treated with hourly eye drops and cyclosporine eye gel. The patient was subsequently treated with vancomycin and rifaximin, with reduction in abdominal pain, bloating and bowel frequency. The patient also reported reduced eye irritation from optical rosacea. The patient then underwent FMT for 10 days (1 colonoscopic infusion, 9 rectal enemas). At 6 months, the patient reported a 75% improvement in GI symptoms and reported ongoing improvement in optical rosacea although still reliant on cyclosporine eye gel. Follow up at one year post FMT demonstrated recurrence of GI symptoms and optical rosacea. Case 2: A female (45yrs) presented with abdominal cramps, bloating, flatulence and alternating diarrhoea and constipation. Concomitant medical history was endometriosis and severe acne rosacea treated with twice daily application of topical mupirocin ointment. Investigations excluded organic pathology and IBS was diagnosed. The patient was subsequently treated with vancomycin and rifaximin followed by FMT for 10 days (1 colonoscopic infusion, 9 rectal enemas). At 6 months, the patient had no ongoing GI symptoms and continued to report ongoing improvement in acne rosacea with some flushing persisting. Follow up at 6 years post FMT demonstrated ongoing clinical improvement with occasional abdominal pain and diarrhoea. The patient no longer experienced acne rosacea and had ceased all medications. Discussion: To our knowledge this is the first report of antibiotics followed by FMT to treat rosacea, with improvements reported in both the short and long term. Future prospective trials are required to confirm FMT as a treatment for rosacea.
Scattering theory and cancellation of gravity-flexural waves of floating plates (2020)

We combine theories of scattering for linearized water waves and flexural waves in thin elastic plates to characterize and achieve control of water wave scattering using floating plates. This requires manipulating a sixth-order partial differential equation with appropriate boundary conditions of the velocity potential. Making use of multipole expansions, we reduce the scattering problem to a linear algebraic system. The response of a floating plate in the quasistatic limit simplifies, considering a distinct behavior for water and flexural waves. Unlike for similar studies in electromagnetics and acoustics, scattering of gravity-flexural waves results in a nonvanishing scattering cross-section in the zero-frequency limit, dominated by its zeroth-order multipole. Potential applications lie in floating structures manipulating ocean water waves.
III-nitride avalanche photodiodes (2007)

Wide bandgap III-Nitride semiconductors are a promising material system for the development of ultraviolet avalanche photodiodes (APDs) that could be a viable alternative to photomultiplier tubes. In this paper, we report the epitaxial growth and physical properties of device quality GaN layers on high quality AlN templates for the first backilluminated GaN p-i-n APD structures on transparent sapphire substrates. The 25 μm x 25 μm device characteristics were measured, and compared with the same devices grown on GaN templates, under low bias and linear mode avalanche operation where they exhibited gains near 1500 after undergoing avalanche breakdown. The breakdown electric field in GaN was determined to be 2.73 MV/cm. The hole impact ionization coefficients were shown to be greater than those of electrons. These APDs were also successfully operated under Geiger mode.
Supplementary Fig 4 from HER2-Mediated Internalization of Cytotoxic Agents in <i>ERBB2</i> Amplified or Mutant Lung Cancers (2023)

&lt;p&gt;Supplementary Fig 4&lt;/p&gt;
EC-MAC: A Cross-Layer Communication Protocol for Dynamic Collaboration in Sensor Networks (2010)

In numerous sensor network applications, a group of nodes surrounding an event (forming an active region) must collaborate to collect locally generated data, reliably and efficiently. Active regions are often characterized by intense data transfer, packet collisions and congestion, resulting in significant network performance loss. Previous studies dealt these scenarios either at the application or network layers, where potential performance gains at the MAC layer were not considered. In this paper, a cross-layer communication protocol Event-Centric MAC (EC-MAC) is introduced in which the channel access time is divided into two intervals. During slot reservation interval, all nodes within an active region collaborate to construct a Transmit/Receive schedule on-the-fly. Once the schedule is in place, data forwarding is performed during the data transmission interval towards a designated root node. By allowing contention-free channel access, EC-MAC outperforms fully awake and LPL-based MAC protocols in terms of both energy efficiency and data throughput.
Astrocyte Overexpression of Heme Oxygenase-1 Improves Outcome After Intracerebral Hemorrhage (2015)

Selective HO-1 overexpression in astrocytes reduces mortality, blood-brain barrier disruption, perihematomal cell injury, and neurological deficits in an autologous blood injection intracerebral hemorrhage model. Genetic or pharmacological therapies that acutely increase astrocyte HO-1 may be beneficial after intracerebral hemorrhage.
Machine Learning Based NLOS Radio Positioning in Beamforming Networks (2022)

In this paper, we address the challenging problem of radio positioning in non-line-of-sight (NLoS) conditions. To this end, we utilize measurements in the form of time-of-flight and gNodeB angular information in the context of 5G New Radio (NR) networks. Such measurements are processed by artificial neural networks with different snapshot and sequence-processing architectures to track the positions of the terminals. For model training, we consider a crowdsensing data acquisition scheme to effortlessly gather the desired measurements with the synchronized location tags. Realistic ray-tracing based evaluations on the so-called Madrid map at 28 GHz millimeter-wave band are provided, to assess the achievable performance while also varying the amount of uncertainties within the data. The obtained results show that radio positioning is feasible with accuracy in the order of 1 meter, or even below, also in challenging NLOS scenarios if the data and measurement uncertainties are small. The results also show that the sequence processing approach offers superior performance under practical measurement uncertainties.
Demonstration of measurement-only blind quantum computing (2016)

Blind quantum computing allows for secure cloud networks of quasi-classical clients and a fully fledged quantum server. Recently, a new protocol has been proposed, which requires a client to perform only measurements. We demonstrate a proof-of-principle implementation of this measurement-only blind quantum computing, exploiting a photonic setup to generate four-qubit cluster states for computation and verification. Feasible technological requirements for the client and the device-independent blindness make this scheme very applicable for future secure quantum networks.
Recomendaciones para la sedación y la analgesia por médicos no anestesiólogos y odontólogos de pacientes mayores de 12 años (2012)

Las complicaciones relacionadas con la sedación son, en su enorme mayoría, prevenibles. El presente documento establece unas recomendaciones para que los no anestesiólogos puedan realizar sedaciones nivel I y II con un buen nivel de seguridad. Sus aspectos más importantes son: administración de la sedación por una persona diferente del operador; recomendaciones en cuanto a la capacitación, la monitorización, el uso de un solo medicamento para la sedación y la disponibilidad de medicamentos y equipos de respaldo; la necesidad de realizar una evaluación previa a la sedación, así como el consentimiento informado y el registro durante el procedimiento; y recomendaciones para considerar un bajo umbral con el fin de solicitar el apoyo de un anestesiólogo. Most of the complications related to sedation are preventable. This document defines some recommendations for non-anesthesiologists so that they can provide sedation level I and II with adequate safety. The most important recommendations are: that the sedation be provided by someone different from the person who performs the surgical procedure; designation of the training and monitoring of thje person who sedates; the use of only one medication for sedation, and the availability of medications and equipment to manage complications; the mandatory need of an assessment prior to the sedation, as well as informed consent and record of events during the procedure; and the recommendation of having a low threshold to request the support of an anesthesiologist.
Milk Fermented by Lactic Acid Bacteria Enhances the Absorption of Dietary Sphingomyelin in Rats (2017)

Supplementation with sphingomyelin has been reported to prevent disease and maintain good health. However, intact sphingomyelin and ceramides are poorly absorbed compared with glycerolipids. Therefore, if the bioavailability of dietary sphingomyelin can be increased, supplementation would be more effective at lower doses. The aim of this study in rats was to evaluate the effect of fermented milk on the bioavailability of dietary sphingomyelin in rats. After the rats had fasted for 15 h, test solutions were administrated orally. Blood samples were collected from the tail vein before and 90, 180, 270, and 360 min after administration. Compared with sphingomyelin/milk phospholipids concentrate (MPL) alone, co-ingestion of sphingomyelin/MPL with fermented milk caused an approximate twofold significant increase in serum ceramides containing d16:1 sphingosine with 16:0, 22:0, 23:0 and 24:0 fatty acids, which was derived from the ingested sphingomyelin. While nonfat milk also increased the serum levels of these ceramides, fermented milk was more effective. Co-ingestion of the upper layer of fermented milk or exopolysaccharide concentrate prepared from fermented milk significantly increased serum ceramide levels. X-ray diffraction analysis also showed addition of fermented milk or EPS concentrate to sphingomyelin eliminated the characteristic peak of sphingomyelin. This study demonstrated for the first time that co-ingestion of dietary sphingomyelin and fermented milk, compared with ingestion of dietary sphingomyelin alone, caused a significant increase in the absorption of sphingomyelin. Our results indicate exopolysaccharides in fermented milk may contribute to inhibition of sphingomyelin crystallization, resulting in enhanced absorption of dietary sphingomyelin in rats.
Sion Power's Licerion ® Batteries (2018)

Sion Power known as developer of high energy Li-S battery is extending its new Licerion ® technology to other electrochemical systems including Li - Intercalation Cathodes. The core of Licerion ® technology is protected metallic lithium anode with several levels of physical and chemical protection. Physical protection is based on ceramic-polymer composite membranes and is combined with specialized cell design and electrolyte systems providing smooth, dendrite-free lithium deposition and chemical protection of exposed metallic lithium surface. This approach addresses safety and cycle life problems that have historically plagued lithium metal electrodes. Sion Power Corporation in collaboration with BASF is working aggressively on realizing the impressive potential of the Licerion ® technology. Current state of development offers highest combination of energy density, specific energy and cycle life: exceeding 1000 Wh/L, 500 Wh/kg and over 350 cycles. Sion Power's new Licerion ® technology is a solution beyond Li-Ion and beyond Li-S and offers diverse battery applications from electric vehicles to stratospheric drones and urban air transportation. This presentation will discuss: Failure mechanisms of rechargeable batteries with metallic lithium anode. Approaches pursued by Sion Power in collaboration with BASF towards next generation of Licerion ® - Sulfur and Licerion ® - Ion batteries. Current status of Licerion ® batteries: their energy, cycle life, high power performance and thermal stability.
A Dynamic Pinhole Aperture Control System (2021)

We have designed prototype control electronics and software responsible for moving adjustable pinhole apertures. With this design we can create various imaging configurations corresponding to desired resolutions and sensitivities in a large imaging system. AdaptiSPECT-C is a dynamic whole-brain imager composed of 24 cameras, each outfitted with five apertures. This system can be adjusted in real-time as part of the data acquisition method for dynamic studies to account for changes in the source activity as a function of time. The control electronics for these apertures are designed to operate a single camera in the assembly and each camera can function independently. The modular design allows movement of multiple apertures for fast setup times and storage of preset configuration for ease of repeatability. The software also handles user input for troubleshooting.
Dichotomous Physiological Effects of Nocturnal External Nasal Dilation in Heavy Snorers: The Answer to a Rhinologic Controversy? (2001)

The purpose of this article was to study the impact of external dilation on nasal airway dimensions, sleep architecture, and snoring. Eighteen heavy snorers without severe obstructive sleep apnea syndrome (mean apnea-hypopnea index (AHI) 9.3) reporting nocturnal nasal obstruction were enrolled in a randomized (controlled) cross-over study, evaluating subjective and objective effects of external nasal dilation (Breathe Right, 3M). The active dilator was also worn during a one-week pretrial run-in period. Polysomnography, recording of snoring sounds, and repeated acoustic rhinometry were performed on two consecutive nights, one with the active dilator and one with a placebo strip. The significant subjective improvement reported during the run-in period compared to the preceding period without dilator (p < 0.01), remained only for nasal patency (p < 0.05) when comparing the two nights in the sleep laboratory. The nasal dimensions increased significantly (p < 0.001) with the active dilator compared to placebo, both in the evening and the next morning. In a subgroup (n = 6) of habitual snorers (AHI < 10) with severe morning obstruction (combined minimal cross-sectional area < 0.6 cm2), external dilation significantly improved the mean sleep PaSO2 (92.4 --> 96.7) and the percentage of sleep with a PaSO2 < 95% (49.9% --> 4.9%) (p < 0.05). In this subgroup there was a trend toward reduction in (7.4 --> 5.4) (p = 0.06), whereas the AHI increased significantly in the group of 12 with larger nocturnal nasal dimensions (p < 0.05). Duration and intensity of snoring remained unchanged regardless of the subgrouping. Objective beneficial effects were restricted to nocturnal oxygen saturation and AHI in a subgroup of habitual heavy snorers identified by repeated acoustic rhinometry, in whom external dilation objectively relieved marked nocturnal nasal obstruction. This finding may provide a logical explanation for the conflicting results of medical, surgical, and mechanical expansion of the nasal dimensions on snoring and sleep disturbances. (American
Chirality and reversible solid state phase transition of a tetranuclear titanium oxido cluster (2013)

The tetranuclear titanium oxido cluster (μ4-oxido)-hexakis(μ-thiophene-2-methoxido)-octakis(thiophene-2-methoxido)-tetra-titanium (1), which has been obtained by the reaction of Ti(OiPr)4 with thiophene-2-methanol in the presence of moisture, consists of a Ti4(μ4-O)(μ-O)6-core and crystallizes as a racemic mixture of two different chiral enantiomers. Compound 1 undergoes a reversible phase transition at 163–168 K in the solid state as evidenced by Powder X-Ray Diffraction (PXRD) and Differential Scanning Calorimetry (DSC). Single-crystal X-ray diffraction studies have been carried out to establish the molecular structure of the high and low temperature phase of 1.
Hypermedia processors: design space exploration (2002)

We present a framework for area optimal system design space exploration for hypermedia applications. We focus on a category of processors that are programmable yet optimized to a hypermedia application. The key components of the framework presented in this paper are a retargetable instruction-level parallelism compiler, instruction level simulators, a set of complete media applications written in a high level language and a media processor synthesis algorithm. The framework addresses the need for area optimal system design by exploiting the instruction-level parallelism found in media applications by compilers that target multiple-instruction-issue processors. Using the framework we conduct an extensive exploration of area optimal system design space for a hypermedia application. We found that there is enough ILP in the typical media and communication applications to achieve highly concurrent execution when throughput requirements are high. On the other hand, when throughput requirements are low, there is no need to use multiple-instruction-issue processors.