gebhart/patrepeval huggingface dataset:
Stabilized hierarchical USY zeolite catalysts for simultaneous increase in diesel and LPG olefinicity during catalytic cracking (2012)

Hierarchical USY zeolites obtained by scalable and affordable post-synthetic modifications (PSM) are stabilized by means of REO ion exchange and/or hydrothermal treatments, leading to FCC catalysts with improved hydrothermal stability, increased bottoms conversion capacity and improved product selectivity, as compared to a conventional commercial USY based catalyst of comparable activity. The stabilized mesoporous USY yields more and better quality diesel with a reduced content of polyaromatic compounds, while producing lower amounts of gases but with a LPG fraction enriched in propene and butenes. The obtained selectivity slate is attributed to the combination of appropriate Brønsted acidity and reduced diffusion pathway in the zeolite crystals. A detailed characterization relates the physico-chemical, textural and morphological changes induced by the PSM to the resulting catalytic behavior.
Plecstatin-1 induces an immunogenic cell death signature in colorectal tumour spheroids (2020)

Organometallic metal(arene) anticancer agents were believed to confer low selectivity for potential cellular targets. However, the ruthenium(arene) pyridinecarbothioamide (plecstatin-1) showed target selectivity for plectin, a scaffold protein and cytolinker. We employed a three-dimensional cancer spheroid model and showed that plecstatin-1 limited spheroid growth, induced changes in the morphology and in the architecture of tumour spheroids by disrupting the cytoskeletal organization. Additionally, we demonstrated that plecstatin-1 induced oxidative stress, followed by the induction of an immunogenic cell death signature through phosphorylation of eIF2α, exposure of calreticulin, HSP90 and HSP70 on the cell membrane and secretion of ATP followed by release of high mobility group box-1.
A High Precision 24 GHz FMCW-Radar using a Phase-Slope Signal Processing Algorithm (2002)

A 24 GHz FMCW-radar system is presented using a phase-slope algorithm for increased range determination accuracy. Additionally a fractional-N ramp generator provides a highly linear frequency ramp with nonlinearities below 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-8</sup> . These highly linear frequency ramps make post measurement error correction feasible. Especially analysing the phase-slope of the i.f. signal results in an increased measurement precision compared to the standard spectral centre algo-rithm. Another important aspect of the high performance FMCW-radar system is the design of the microwave circuit.
Table S1 from Spatial Mapping and Immunomodulatory Role of the OX40/OX40L Pathway in Human Non–Small Cell Lung Cancer (2023)

&lt;p&gt;Supplementary Table S1&lt;/p&gt;
Simple Modeling of an Abdomen of Pregnant Women and Its Application to SAR Estimation (2006)

This paper presents a simple abdomen model of pregnant women and the evaluation of the specific absorption rate (SAR) inside the proposed model close to normal mode helical antennas (NHAs), which are replacing the portable radio terminals for business at 150MHz. First, dielectric properties of amniotic fluid and those of fetus of rabbit, which have about the same electrical properties as human, are measured. As a result, the conductivity of amniotic fluid is 1.8 times and that of fetus is 1.3 times higher than that of adult muscle at 150MHz. The result also suggests the modeling of pregnant women including the amniotic fluid and the fetus is necessary. Next, a simple abdomen model of pregnant women based on the measurements of magnetic resonance (MR) images of Japanese women in the late period of pregnancy is proposed. Finally, the SAR inside the proposed abdomen model close to 0.11λ and 0.18λ NHAs is calculated using the finite-difference time-domain (FDTD) method. As a result, we have confirmed that the 10-g average SAR in the fetus is sufficiently less than 2 W/kg, when the output power of NHAs is 5 W, which is the maximum nower of portable radio terminals in Japan.
Self-Organization of TiO2Nanoparticles in Thin Films (1998)

Nanocrystalline titanium dioxide colloids have been synthesized using a sol−gel technique followed by growth under hydrothermal conditions in a basic environment at temperatures between 190 and 270 °C. Thin films have been made from aqueous suspensions of these colloids. X-ray analysis showed the colloids to be primarily the anatase crystal phase. Scanning electron microscopy (SEM) revealed a predominantly rodlike particle morphology after growth at lower temperatures and the formation of principally truncated tetragonal or tetrahydral bipyramidal nanocrystallites following growth at higher temperatures. The rodlike particles self-organize into regular cubic arrays with the long axis of the rods aligned perpendicular to the film surface. This self-organization is dependent upon the base used in colloidal synthesis and also upon the dielectric constant of the medium used during film formation.
Rhodium Dinaphthocyclooctatetraene Complexes: Synthesis, Characterization and Catalytic Activity in [5+2] Cycloadditions (2012)

Hochaktiv und kompatibel: Eine Ni0-katalysierte [2+2+2+2]-Cycloaddition führt zur effizienten skalierbaren Synthese des Liganden Dinaphtho[a,e]cyclooctatetraen (dnCOT). dnCOT koordiniert mit RhI zu [Rh(dnCOT)(MeCN)2]SbF6 (siehe Schema), einem exzellenten Katalysator für [5+2]-Cycloadditionen von Vinylcyclopropanen mit π-Systemen, der außerordentlich kompatibel mit funktionellen Gruppen ist. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
Templated Crosslinked Imidazolyl Acrylate for Electronic Detection of Nitroaromatic Explosives (2012)

Abstract A low‐voltage operable, highly sensitive, and selectively responsive polymer for the detection of nitroaromatic explosives is investigated. Resistive devices are fabricated by simple spin‐coating on flexible and transparent substrates in addition to silicon substrates and are stable under ambient temperature and oxygen levels before exposure to the nitroaromatics. After exposure to 2,4,6‐trinitrotoluene (TNT), the devices show increased conductance, even with picogram (pg) quantities of TNT, accompanied by a confirming color change from colorless to deep red. The relative conductance increase per unit exposure is the highest yet reported for TNT. Aromatic anion salts, on the other hand, do not induce any electronic responses. 1 H NMR and microscopic analyses show chemical interactions and morphological changes correlated with the electronic responses, some of which are specific to TNT in relation to other nitroaromatics. The binding constant for the imidazole rings and TNT is on the order of tens of M −1 . The materials are promising for rapid indication of exposure to nitroaromatic compounds.
Novel Biomolecular NanoPhotonic Devices, Sensors, Photonic Nanocrystals and Biochips: Advances in Medical Diagnostics, Environmental and Defense (2007)

This experimental study explores the potential of insulin molecules and other proteins, enzymes and dipolar ions, alone, or in conjunction with colloidal gold nanoparticles and other nanoparticles to modulate and enhance the detection process of optical signals by providing unique signal characteristics, such as optical gain, light shaping, and optical control capabilities. The experimental results of this study indicate that insulin molecules can be used to enhance and amplify incoming light photon signals. Further signal amplification and enhancement has been observed by doping insulin molecules with colloidal gold nanoparticles. These observations have significant implications on the development of novel biomolecular photonic materials, optical devices, sensors, nanodevices, therapeutical and imaging systems.
Function and inhibition sensitivity of the N-terminal segment of surfactant protein B (SP-B1-25) in preterm rabbits (2001)

These experiments suggest that the N-terminal domain of SP-B (SP-B1-25) exhibits in vitro and in vivo surface activity and is relatively insensitive to plasma inhibition.
Nonlinear light absorption of polymethine dyes in liquid and solid media (1998)

We investigate nonlinear optical absorption of a series of polymethine dyes in liquid solution and in a solid poly(urethane acrylate) elastopolymer host. Depending on the ratio between the absorption cross section from the ground to the first excited state (σ01) and from the first to the higher excited states (σ12) and on the pump wavelength, they demonstrate absorption that either increases or decreases with increasing incident energy density. Our interest is directed at studying the optical limiting behavior of the dyes for sensor protection applications, which requires that σ12 be greater than σ01. We performed a detailed investigation of the dynamics of these processes, using Z-scan and pump–probe techniques at the single wavelength of 532 nm. We obtained σ12/σ01≈80 for one of the dyes, which is significantly higher than any previously reported value of which we are aware. The linear absorption remained significant, a requirement for good optical limiting. However, at high incident energy density for most of the dyes the increasing absorption converted to a bleaching effect with repeated irradiation. This effect was reversed after several seconds in liquid solutions and several minutes in the polymer host, possibly because of replenishment of the dye by diffusion in both media.
Pulsed Sonoelectrochemical Synthesis of Size-Controlled Copper Nanoparticles Stabilized by Poly(N-vinylpyrrolidone) (2006)

A novel sonoelectrochemical method for the size-controlled synthesis of spherical copper nanoparticles in an aqueous phase was developed. In this study, poly(N-vinylpyrrolidone) (PVP) was used as the stabilizer for the copper clusters. The copper nanoparticles were characterized by XRD, UV-vis, IR, DLS, TEM, and HRTEM. The PVP was found to greatly promote the formation rate of copper particles and to significantly reduce the copper deposition rate, thereby making monodispersed copper nanoparticles. We could control the particle size by adjusting various parameters such as current density, deposition, temperature, and sonic power, and improve the homogeneity of the copper particles. The results also showed that the transfer rate of PVP-stabilized copper clusters from the cathodic vicinity to the bulk solution played an important role in the preparation of the monodispersed nanoparticles.
γ-Glutamyltranspeptidase-Mediated Degradation of Diclofenac-S-acyl-glutathione in Vitro and in Vivo in Rat (2008)

Diclofenac, a nonsteroidal antiinflammatory drug, is known to be metabolized to chemically reactive intermediates that transacylate GSH forming diclofenac-S-acyl-glutathione (D-SG) in vivo in rat and in vitro in rat and human hepatocytes. Recently, it was reported that the treatment of rats with diclofenac led to a substantial decrease in the activity of hepatic gamma-glutamyltranspeptidase (gamma-GT), an extracellular canalicular membrane enzyme. Because studies have indicated that D-SG is a chemically reactive transacylating species that is excreted into rat bile, we propose that D-SG formed in the liver may be a substrate for, and potential inhibitor of, hepatic gamma-GT. The present experiments were performed to investigate the ability of D-SG to be a substrate for gamma-GT in vivo in rat and in vitro with commercially available gamma-GT enzyme. We also examined the ability of D-SG to inhibit gamma-GT in vitro. Thus, LC-MS/MS analysis of bile extracts from diclofenac-dosed rats (200 mg/kg, iv) showed the presence of the gamma-GT-mediated D-SG degradation product diclofenac-N-acyl-cysteinylglycine (D- N-CG), where a total of approximately 8 microg was excreted 6 h postadministration. When D-SG (100 microM) was incubated with gamma-GT (1 unit/mL), the GSH adduct was degraded in a linear time-dependent fashion where approximately 94 microM D- N-CG was formed after 20 min of incubation. Dialysis studies showed that inhibition of gamma-GT by D-SG was completely reversible. Further inhibition studies showed that D-SG is a competitive inhibitor of the gamma-GT enzyme. Results from theses studies indicate that D-SG is a substrate for gamma-GT; however, the conjugate may not contribute significantly to the decrease in gamma-GT activity reported to occur in vivo in rat.
Diabetes Mellitus: Diagnosis and Classification (2001)

While the clinical symptoms of diabetes mellitus vary and are not of themselves reliable indicators of the disorder, when they are present the diagnosis of diabetes can be confirmed by a single unequivocally elevated blood glucose measurement. Hyperglycemia by itself may be transitory and for the asymptomatic person at least one additional blood glucose measurement with a value in the diabetic range is essential for diagnosis. The oral glucose tolerance test is one of the most widely used and misused methods of diagnosis but may be difficult to perform and for epidemiological studies a single 2 h value after an overnight fast often suffices. The new diagnostic criteria for fasting plasma blood glucose concentrations and the revised classifications for diabetes proposed by the American Diabetes Association and the World Health Organization are discussed. The new etiological types that may result in diabetes mellitus include Type 1, Type 2, immune-mediated, genetic, pancreatic disorders, virally associated and gestational.
Evolution and competition between chiral spin textures in nanostripes with D 2d symmetry (2020)

Chains of antiskyrmions and elliptical skyrmions are stabilized in nanostripes along several crystallographic directions.
Mobile ad hoc networking and the IETF (1998)

This article provides a snapshot of work underway within the Mobile Ad hoc NETworks (MANET) Working Group of the Internet Engineering Task Force (IETF). The article presents some issues currently under discussion on the MANET mailing list, and also summarizes the proceedings of the last MANET WG meeting.
ChemInform Abstract: The Story of Lescol: From Research to Production (2002)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
High resolution depth-resolved imaging from multi-focal images for medical ultrasound (2015)

An ultrasound imaging technique providing sub-diffraction limit axial resolution for point sources is proposed. It is based on simultaneously acquired multi-focal images of the same object, and on the image metric of sharpness. The sharpness is extracted by image data and presents higher values for in-focus images. The technique is derived from biological microscopy and is validated here with simulated ultrasound data. A linear array probe is used to scan a point scatterer phantom that moves in depth with a controlled step. From the beamformed responses of each scatterer position the image sharpness is assessed. Values from all positions plotted together form a curve that peaks at the receive focus, which is set during the beamforming. Selection of three different receive foci for each acquired dataset will result in the generation of three overlapping sharpness curves. A set of three calibration curves combined with the use of a maximum-likelihood algorithm is then able to estimate, with high precision, the depth location of any emitter fron each single image. Estimated values are compared with the ground truth demonstrating that an accuracy of 28.6 μm (0.13λ) is achieved for a 4 mm depth range.
EGFR signal transactivation in cancer cells (2003)

The EGFR (epidermal growth factor receptor) plays a key role in the regulation of essential normal cellular processes and in the pathophysiology of hyperproliferative diseases such as cancer. Recent investigations have demonstrated that GPCRs (G-protein-coupled receptors) are able to utilize the EGFR as a downstream signalling partner in the generation of mitogenic signals. This cross-talk mechanism combines the broad diversity of GPCRs with the signalling capacities of the EGFR and has emerged as a general concept in a multitude of cell types. The molecular mechanisms of EGFR signal transactivation involve processing of transmembrane growth factor precursors by metalloproteases which have been recently identified as members of the ADAM (a disintegrin and metalloprotease) family of zinc-dependent proteases. Subsequently, the EGFR transmits signals to prominent downstream pathways, such as mitogen-activated protein kinases, the phosphoinositide 3-kinase/Akt pathway and modulation of ion channels. Analysis of GPCR-induced EGFR activation in more than 60 human carcinoma cell lines derived from different tissues has demonstrated the broad relevance of this signalling mechanism in cancer. Moreover, EGFR signal transactivation was linked to diverse biological processes in human cancer cells, such as cell proliferation, migration and anti-apoptosis. Together with investigations revealing the importance of this GPCR-EGFR cross-talk mechanism in cardiac hypertrophy, Helicobacter pylori -induced pathophysiological processes and cystic fibrosis, these findings support an important role for GPCR ligand-dependent EGFR signal transactivation in diverse pathophysiological disorders.
Human-Computer Collaboration for Visual Analytics: an Agent-based Framework (2023)

The visual analytics community has long aimed to understand users better and assist them in their analytic endeavors. As a result, numerous conceptual models of visual analytics aim to formalize common workflows, techniques, and goals leveraged by analysts. While many of the existing approaches are rich in detail, they each are specific to a particular aspect of the visual analytic process. Furthermore, with an ever-expanding array of novel artificial intelligence techniques and advances in visual analytic settings, existing conceptual models may not provide enough expressivity to bridge the two fields. In this work, we propose an agent-based conceptual model for the visual analytic process by drawing parallels from the artificial intelligence literature. We present three examples from the visual analytics literature as case studies and examine them in detail using our framework. Our simple yet robust framework unifies the visual analytic pipeline to enable researchers and practitioners to reason about scenarios that are becoming increasingly prominent in the field, namely mixed-initiative, guided, and collaborative analysis. Furthermore, it will allow us to characterize analysts, visual analytic settings, and guidance from the lenses of human agents, environments, and artificial agents, respectively.
P‐34: Image Quality Impact of Pixel Patterns and Image Processing Algorithms for RGBW OLED Displays (2005)

Abstract Several RGBW pixel patterns were simulated with different RGB to RGBW color conversion approaches, and the resulting image quality was quantifiably compared to RGB pixel patterns. The image quality of select RGBW pixel patterns was found to be comparable or slightly higher than traditional RGB pixel patterns having the same number of pixels.
Synergistic electronic coupling/cross-talk between the isolated metal halide units of zero dimensional heterometallic (Sb, Mn) halide hybrid with enhanced emission (2021)

Reported here is a heterometallic 0D hybrid with constituent isolated metal halide units (Sb, Mn) that show strong synergistic interaction/coupling between the metal halide units (through Sb → Mn energy transfer) that results in enhanced emission.
Phenylpyropene C, a New Inhibitor of Acyl-CoA: Cholesterol Acyltransferase Produced by Penicillium griseofulvum F1959. (2002)

Acyl-CoA: cholesterol acyltransferase (ACAT, EC 2.3.1.26) is responsible for intracellular esterification of cholesterol and plays a key role in intestinal absorption of cholesterol, hepatic production of lipoproteins1,2) and accumulation of cholesteryl esters within macrophages and smooth muscle cells of the atheroma3). Therefore, ACAT is an attractive target for new treatments of hypercholesterolemia and atherosclerosis4). In the course of our search for ACAT inhibitors from microbial sources, phenylpyropene C was isolated from the fermentation broth of Penicillium griseofulvum F1959. It was deposited in the Korean Collection for Type Culture (KCTC), Korea, as KCTC 0387BP.
Sequential diastereoselective addition and allylic azide isomerization of syn- and anti-.alpha.-azido-.beta.-(dimethylphenylsilyl)-(E)-hex-4-enoates with acetals: asymmetric synthesis of .gamma.-hydroxy-.alpha.-amino acid synthons (1992)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSequential diastereoselective addition and allylic azide isomerization of syn- and anti-.alpha.-azido-.beta.-(dimethylphenylsilyl)-(E)-hex-4-enoates with acetals: asymmetric synthesis of .gamma.-hydroxy-.alpha.-amino acid synthonsJames S. Panek, Michael Yang, and Itzhak MulerCite this: J. Org. Chem. 1992, 57, 15, 4063–4064Publication Date (Print):July 1, 1992Publication History Published online1 May 2002Published inissue 1 July 1992https://pubs.acs.org/doi/10.1021/jo00041a002https://doi.org/10.1021/jo00041a002research-articleACS PublicationsRequest reuse permissionsArticle Views247Altmetric-Citations22LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
A New Aluminum-Silicon/Boron Nitride Powder for Clearance Control Applications (1998)

Abstract Abradable coatings are used in gas-turbine engines to optimize compressor performance by maintaining tight blade tip clearances. The most common such coatings are thermally sprayed Al-Si/polyester, Al-Si/graphite, and Ni/graphite. Al-Si/graphite coatings have performed well in terms of wear but are prone to corrosion, which can lead to spalling and a reduction in engine efficiency. In this paper, we chart the development of a powder-based Al-Si/BN abradable material designed to overcome in-service corrosion and analyze laboratory and engine testing results.