gebhart/patrepeval huggingface dataset:
Rules-based correction strategies setup on sub-micrometer line and space patterns for 200mm wafer scale SmartNIL process within an integration process flow (2017)

In this paper the rules-based correction strategies for the nanoimprint lithography (NIL) technology are addressed using complete Scanning Electron Microscopy (SEM) characterizations. Performed onto 200 mm wafers imprinted with the HERCULES NIL equipment platform, Critical Dimension (CD) uniformity analyses are used to measure the evolution of lines and spaces features dimensions from the master to 50 consecutive imprints. The work brings focus on sub micrometer resolution features with duty cycles from 3 to 7. The silicon masters were manufactured with 193 optical lithography and dry etching and were fully characterized prior to the imprint process. Repeatability tests were performed over 50 wafers for two different processes to collect statistical and comparative data. The data revealed that the CD evolutions can be modelled by quadratic functions with respect to the number of imprints and feature dimension (CD and pitch) on the master. These models are used to establish the rules-based corrections for lines arrays in the scope of nanoimprint master manufacturing, and it opens the discussion on the process monitoring through metrology for the nanoimprint soft stamp technologies.
Supplementary Figure S1 from High-Density Single Nucleotide Polymorphism Array Defines Novel Stage and Location-Dependent Allelic Imbalances in Human Bladder Tumors (2023)

Supplementary Figure S1 from High-Density Single Nucleotide Polymorphism Array Defines Novel Stage and Location-Dependent Allelic Imbalances in Human Bladder Tumors
The effects of lovastatin on neointimal hyperplasia following injury in a porcine coronary artery model. (1996)

Although lovastatin produced a statistically significant decrease in neointimal thickness post-balloon angioplasty, when extrapolated to angiographical end-points, the differences would not be clinically significant. These data suggest that lovastatin may be of marginal use in humans for limiting restenosis.
Study of Joint Resistance in ${\hbox{Nb}}_{3}{\hbox{Al-NbTi}}$ Superconducting Joint for High Field NMR (2007)

We have developed a novel superconducting joint method for Nb <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> Al conductors, which can be used for the innermost coil of a 1-GHz NMR magnet. First, we optimized the joint property; then, we prepared a closed circuit with an NbTi coil and a pair of Nb <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">3</sub> Al-NbTi joints; finally, we determined the joint resistance by using the field decay of the persistent current. A joint resistance of 1.27 times 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-12</sup> Omega was obtained, which is sufficiently low for high field NMR.
The immune-stimulation capacity of liposome-treated red blood cells (2017)

Our in vivo studies on a rat model established safety of transfusing liposome-treated red blood cells (RBCs) but identified the potential for immune modulation as related to transfusion efficacy of liposome-treated RBCs. The aim of this study was at assessing the impact of liposome-induced membrane changes on the immune profile of liposome-treated RBCs by (a) evaluating their interaction with endothelial cells and monocytes; and (b) the resulting immune response derived from this interaction, in the form of cytokine release, adhesion molecules expression and phagocytosis. Unilamellar liposomes were synthesized to contain unsaturated phospholipids (1,2-dioleoyl-sn-glycero-3-phosphocholine [DOPC]:CHOL, 7:3 mol%). The human RBCs immune profile was assessed by incubating control and DOPC-treated RBCs with human umbilical vein endothelial cells (HUVECs) and monocytes. Cytokine release measured by Luminex technology, vascular cell adhesion molecule (VCAM)-1 and E-selectin on HUVECs measured by flow cytometry, and the erythrophagocytic activity of monocytes by monocyte monolayer assay (MMA) were determined. Fibroblast growth factor [FGF]-2 was the only cytokine released by HUVECs that remained increased after incubation with DOPC-treated RBCs compared to control throughout storage. The expression of both VCAM-1 (15.3 ± 5.6% versus 6.3 ± 0.9%, p = 0.008) and E-selectin (18.0 ± 6.3% versus 6.6 ± 0.7%, p = 0.004) by HUVECs were significantly increased after incubation with DOPC-treated RBCs at day 2 of storage. The MMA resulted in phagocytic indexes of zero for both control and DOPC-treated RBCs at day 2 and 42 of storage. The liposome treatment did not result in significant changes to the immune profile of stored DOPC-treated RBCs. These findings combined with previous in vivo results, make liposome treatment a potential candidate for application in RBC preservation and open the possibility for clinical use with other cell types.
Application of link layer FEC to DVB-S2 for railway scenarios (2008)

In this paper, we analyze the performance improvement of the Second Generation Digital Video Broadcasting via Satellite (DVB-S2) when applying Forward Error Correction (FEC). DVB-S2 was designed for fixed terminals and thus we apply FEC at the Link Layer (LL) level in order to achieve reliable reception in mobile environment. Specifically, we focus on the railway scenario and analyze the performance and compatibility of the different LL-FEC schemes already available in the DVB family of standards: Multiple Protocol Encapsulation-FEC (MPE-FEC), MPE-FEC Sliding Encoding and MPE Inter-Burst FEC (MPE-IFEC). These are analyzed and compared when adopting Reed-Solomon (RS) or Raptor FEC Codes. A simulation framework for LL-FEC over DVB-S2 systems is presented and an optimization of FEC code parameters is proposed. Two typical railway scenarios have been analyzed: Line-of-Sight together with the effect of Power Archers (LOS+PA) and non-Line of Sight (nLOS). Theoretical analysis and simulation revealed that LL-FEC can overcome the fade in the railway scenarios in case appropriate FEC codes parameters are used.
Voltage Propagation in Inverter-driven Machine Windings over Wide Operation Range (2020)

This paper studies the pulse voltage propagation inside machine windings driven by power inverters. The fast switching of devices in the inverter generates voltage pulses with high dv/dt and induces high overshoots at the machine winding terminals. Those high voltage overshoots can accelerate the degradation of the winding insulation system. This work analyzes how the steep-front voltage distributes along the windings during switching transients over a wide range of operation conditions. Circuit analysis is conducted for each transition of switching events over an entire fundamental cycle. An 8-pole interior permanent magnet synchronous machine for hybrid electric vehicle traction applications with a complex winding structure was used to verify the analysis. Tests were conducted to obtain the pulse voltage propagation along the machine winding at all the transition of switching events over an entire fundamental cycle when the machine was working at certain operating points. The effect of multiple factors on the pulse winding voltage propagation were tested and analyzed in this work, such as DC voltage level, current level, rotor speed, etc. Then, the voltage stress was mapped on each part of the winding insulation along the winding for various machine operating points, which quantifies the maximum voltage stress distribution on the winding insulation system. The understanding of the voltage stress distribution gained from this study will be applied to guide optimization of electric machine winding insulation in the future.
A Monoclonal Antibody Against Migration Inhibitory Factor (MIF) Obtained by Immunization With MIF From the Human Lymphoblast Cell Line Mo (1986)

A monoclonal antibody-secreting hybrid cell line, E7, was constructed from myeloma cells and spleen cells from BALB/c mice immunized with partially purified human MIF from culture fluid of the human T-lymphoblast cell line Mo. The hybrid cell line E7 was selected by screening hybridoma cultures for their capacity to adsorb added MIF activity when assayed together with rabbit anti-mouse IgG-coupled to protein A-Sepharose. The monoclonal antibody produced by the cloned hybridoma E7 also directly neutralized MIF activity from Mo cells and two species of MIF from the culture fluid of human peripheral blood lymphocytes, but did not neutralize IFN-gamma from Mo cells and from human peripheral blood lymphocytes. This antibody reacted also with a component in phytohemagglutinin preparations with an apparent molecular weight of 60,000; however, it did not react with the active tetramer of phytohemagglutinin.
High‐pressure torsion of SiO 2 quartz sand: Phase transformation, optical properties, and significance in geology (2020)

Abstract Phase transformation and optical properties of silica (silicon dioxide, SiO 2 ) quartz sand under high pressure/temperature has been of interest in geology and optical physics for many years. In this study, besides high pressure/temperature, high plastic strain is simultaneously applied to the quartz sand by high‐pressure torsion (HPT) processing. The material shows oxygen vacancy formation and transformation to (a) a denser nanocrystalline quartz phase, (b) a high‐temperature amorphous phase and (c) a high‐pressure coesite phase. These structural and microstructural changes lead to light absorbance, electron spin resonance, photoluminscence and photocatalytic activity, while these changes are enhanced by increasing strain. This study introduces a possible pressure‐temperature‐strain‐based mechanism for the formation of naturally observed vacancies and coesite phase in SiO 2 ‐based minerals and sands.
Contrast-induced nephropathy and nephrogenic systemic fibrosis: minimizing the risk. (2012)

The associated risks of contrast-enhanced, cross-sectional imaging has created significant challenges for urologic evaluation. We propose an evidence-based approach to guide patient therapy, which can minimize patient risk and physician anxiety, while simplifying the decision-making process.
A convenient large-scale synthesis of 5-methoxyflavone and its application to analog preparation (1993)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTA convenient large-scale synthesis of 5-methoxyflavone and its application to analog preparationJeffrey J. Ares, Pamela E. Outt, Sunil V. Kakodkar, Robert C. Buss, and Jeffrey C. GeigerCite this: J. Org. Chem. 1993, 58, 27, 7903–7905Publication Date (Print):December 1, 1993Publication History Published online1 May 2002Published inissue 1 December 1993https://pubs.acs.org/doi/10.1021/jo00079a041https://doi.org/10.1021/jo00079a041research-articleACS PublicationsRequest reuse permissionsArticle Views911Altmetric-Citations41LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information Get e-Alerts
Electron spin resonance (ESR) probe for interventional MRI instrument localization (1999)

This article presents a miniaturized electron spin resonance (ESR) probe for deducing the position of a surgical instrument on an MR image. The ESR probe constructed was small enough to fit inside a 14-G biopsy needle sheath, and position information of the sheath could be acquired using a simple gradient sequence. The position accuracy was estimated from needle trajectories as inferred from the needle artifact, the actual physical trajectory, and measured coordinates. The probe was able to track the tip of a biopsy needle quickly (10 samples/sec) and precisely with accuracy better than ±2 mm. J. Magn. Reson. Imaging 1999;10:216–219. © 1999 Wiley-Liss, Inc.
Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity (2022)

The non-classical class Ib molecule human leukocyte antigen E (HLA-E) has limited polymorphism and can bind HLA class Ia leader peptides (VL9). HLA-E-VL9 complexes interact with the natural killer (NK) cell receptors NKG2A-C/CD94 and regulate NK cell-mediated cytotoxicity. Here we report the isolation of 3H4, a murine HLA-E-VL9-specific IgM antibody that enhances killing of HLA-E-VL9-expressing cells by an NKG2A<sup>+</sup> NK cell line. Structural analysis reveal that 3H4 acts by preventing CD94/NKG2A docking on HLA-E-VL9. Upon in vitro maturation, an affinity-optimized IgG form of 3H4 showes enhanced NK killing of HLA-E-VL9-expressing cells. HLA-E-VL9-specific IgM antibodies similar in function to 3H4 are also isolated from naïve B cells of cytomegalovirus (CMV)-negative, healthy humans. Thus, HLA-E-VL9-targeting mouse and human antibodies isolated from the naïve B cell antibody pool have the capacity to enhance NK cell cytotoxicity.
Coronary flow reserve: noninvasive measurement in humans with breath-hold velocity-encoded cine MR imaging. (1996)

Breath-hold velocity-encoded cine MR imaging provided reproducible assessment of coronary flow reserve in humans.
Linear variable filter based oil condition monitoring systems for offshore windturbines (2011)

A major part of future renewable energy will be generated in offshore wind farms. The used turbines of the 5 MW class and beyond, often feature a planetary gear with 1000 liters lubricating oil or even more. Monitoring the oil aging process provides early indication of necessary maintenance and oil change. Thus maintenance is no longer time-scheduled but becomes wear dependent providing ecological and economical benefits. This paper describes two approaches based on a linear variable filter (LVF) as dispersive element in a setup of a cost effective infrared miniature spectrometer for oil condition monitoring purposes. Spectra and design criteria of a static multi-element detector and a scanning single element detector system are compared and rated. Both LVF miniature spectrometers are appropriately designed for the suggested measurements but have certain restrictions. LVF multi-channel sensors combined with sophisticated multivariate data processing offer the possibility to use the sensor for a broad range of lubricants just by a software update of the calibration set. An all-purpose oil sensor may be obtained.
Transient Thermal Response of Servers Through Air Temperature Measurements (2013)

Transient CFD analysis of data centers requires appropriate representations of the transient thermal characteristics of servers. Thermal conductance and thermal capacitance are two determining characteristics for the response of servers under unsteady conditions. Previous studies proposed tests that require detailed temperature and thermal capacitance measurements for each of the server component, requiring access to individual components inside the server. In this paper, we propose a method for obtaining the transient thermal characteristics of a server from server inlet and outlet temperatures under transient operating conditions.
Microseismic events enhancement and detection in sensor arrays using autocorrelation‐based filtering (2017)

ABSTRACT Passive microseismic data are commonly buried in noise, which presents a significant challenge for signal detection and recovery. For recordings from a surface sensor array where each trace contains a time‐delayed arrival from the event, we propose an autocorrelation‐based stacking method that designs a denoising filter from all the traces, as well as a multi‐channel detection scheme. This approach circumvents the issue of time aligning the traces prior to stacking because every trace's autocorrelation is centred at zero in the lag domain. The effect of white noise is concentrated near zero lag; thus, the filter design requires a predictable adjustment of the zero‐lag value. Truncation of the autocorrelation is employed to smooth the impulse response of the denoising filter. In order to extend the applicability of the algorithm, we also propose a noise prewhitening scheme that addresses cases with coloured noise. The simplicity and robustness of this method are validated with synthetic and real seismic traces.
A compact wavelength stabilization scheme for telecommunication transmitters (2002)

With the 100/200 GHz channel spacing of current commercial DWDM systems, severe restrictions are imposed on transmitter wavelengths in order to meet crosstalk specifications and ensure reliable operation of the system in all conditions of its 25 years lifetime. While very stable in the short-term, free-running DFB laser transmitters are expected to exhibit long-term wavelength drifts exceeding these requirements, leading to a need for practical wavelength monitoring and control. In this paper we describe a compact dither free wavelength stabilization method based on a Fabry-Perot (FP) filter. While the concept can be implemented in a stand-alone unit, its small footprint allows its incorporation into existing laser modules without increasing either real estate or dissipated power.
Quantifying highly efficient incoherent energy transfer in perylene-based multichromophore arrays (2015)

Multichromophore perylene arrays were designed and synthesized to have extremely efficient resonance energy transfer. Using broadband ultrafast photoluminescence and transient absorption spectroscopies, transfer timescales of approximately 1 picosecond were resolved, corresponding to efficiencies of up to 99.98%. The broadband measurements also revealed spectra corresponding to incoherent transfer between localized states. Polarization resolved spectroscopy was used to measure the dipolar angles between donor and acceptor chromophores, thereby enabling geometric factors to be fixed when assessing the validity of Förster theory in this regime. Förster theory was found to predict the correct magnitude of transfer rates, with measured ∼2-fold deviations consistent with the breakdown of the point-dipole approximation at close approach. The materials presented, along with the novel methods for quantifying ultrahigh energy transfer efficiencies, will be valuable for applications demanding extremely efficient energy transfer, including fluorescent solar concentrators, optical gain, and photonic logic devices.
P849 Urease-positive proteobacteria in Crohn’s disease identified by novel ex vivo mucosal microbe culture combined with metagenomic sequencing (MC-MGS): the ENIGMA study (2019)

Longitudinal 16S analysis of Australian Crohn’s disease patients suggest that the presence of Proteus spp. is predictive of, and associated with, Crohn’s disease recurrence after intestinal resection.1 This bacterium is remarkable for its urease production, recently identified as a key functional change.2 Further characterisation of the mucosa associated microbiome (MAM) using metagenome sequencing has been limited by the overwhelming presence of human DNA. Here, we present a novel approach, microbe-culture metagenome sequencing (MC-MGS), to characterise and confirm bacteria associated with urease activity in the mucosa-associated microbiota in Crohn’s disease. Anastomotic biopsies from 5 Crohn’s disease patients 6 months post-surgery, were stored in RNA later for DNA extraction. Matched biopsies stored in an anaerobically prepared glycerol buffer underwent microbe culture with a habitat-simulating medium (37ºC, 24 h). Total and microbe enriched biopsy DNA, as well as MC-DNA, was sequenced to a depth of 3 gbp as 150 bp paired-end reads with the Illumina NextSeq500 platform. In addition to metagenome-assembled genomes produced using MetaBAT,3 urease-producing (and other) bacteria were isolated using selective media under aerobic and anaerobic conditions. MC-MGS produced 16 metagenome assembled genomes representing a broad diversity of bacteria representing both facultative and fastidious anaerobes, including members of the Proteeae tribe (Providencia/Morganella). Axenic isolates of urease-positive bacteria were also recovered from the cultures produced from 3/5 biopsies, and included strains of Klebsiella pneumoniae, Escherichia fergusonii, Morganella morganii and Enterococcus faecium. Urease-positive bacteria, principally members of the Enterobacteriaceae are associated with Crohn’s disease. New combined culture and metagenomic sequencing techniques provide a holistic and functional characterisation of the IBD mucosa-associated microbiota, while also providing metagenome-assembled genomes, microbial consortia, and axenic isolates relevant to understanding Crohn’s disease pathophysiology. This work is supported by The Leona M. and Harry B. Helmsley Charitable Trust References 1. Wright EK, et al., Microbial factors associated with postoperative Crohn’s disease recurrence. J Crohn's Colitis 2017;11:191–203. 2. Ni J, et al. A role for bacterial urease in gut dysbiosis and Crohn's disease. Sci Transl Med 2017:9. 3. Kang DD, Froula J, Egan R, et al. MetaBAT, an efficient tool for accurately reconstructing single genomes from complex microbial communities. PeerJ 2015;3:e1165.
Distributed SFC control operation (2020)

Service function chaining (SFC) allows the instantiation of an ordered
set of service functions and subsequent steering of traffic through
them. In order to set up and maintain SFC instances, a control plane
is required, which typically is centralized. In certain environments,
such as fog computing ones, such centralized control might not be
feasible, calling for distributed SFC control solutions. This document
describes a general framework for distributed SFC operation.
Effect of ambient pressure on laser welding of AlSi10Mg fabricated by selected laser melting (2022)

This work attempted to introduce high pressure to reduce pore generation in laser welding of selective laser melted AlSi10Mg, which is different from the traditional approach where the vacuum was preferred in laser welding of aluminum alloys. To understand these phenomena, the impacts of laser welding parameters and ambient pressure on the porosity and weld geometry were examined. Porosity ratio was found linearly increasing with the laser power or linear energy. High-speed imaging revealed that the large pores were formed by multiple merging of small pores, which explained the decrease in fine porosity (<20 μm) but increase in coarse porosity (50–100 μm) when increasing laser power or linear energy. The vacuum ambiance significantly enlarged the pores (up to ∼400 μm) and formed narrow and deep welds. As pressure increased from 0.1 MPa to 0.4 MPa, the porosity ratio was dramatically decreased from ∼10.2% to ∼2.3% accompanied by a decline in porosity size and weld penetration depth. Numerical simulation results revealed that the shallowed weld penetration under high-pressure ambiance was attributed to the decreased recoil pressure, and the reduced porosity ratio was resulted from the high pressure which limited pore growth and merging.