gebhart/patrepeval huggingface dataset:
Innovative RF Device Technologies for Advanced Information and Communications Network Society (2022)

This paper describes the innovation of RF device technologies for wireless communication. Over the last decade, data traffic on the internet has increased exponentially. In particular, data traffic over wireless networks has exploded due to IoT including mobile phones. Since the 1990s, global wireless communication systems and personal cellular services, have evolved from 1G to 4G in order to meet the huge demand for wireless communication. Recently we are focusing on the research and development of devices and amplifiers for 5G, which is being implemented, and beyond 5G and 6G, which are on the horizon. The 5G system consists of many macro cells and small cells, and its power consumption is enormous. The high efficiency and high- power density of GaN devices decreases the power consumption of the whole system. Up to now, ongoing research on N-polar GaN has demonstrated an extremely high-power and high PAE at W-band. Recently we demonstrated innovative high-k MIS N-polar GaN HEMTs which were fabricated, for the first time, using commercial 4-inch wafer process facilities. We overcame the challenge of developing a vital gate insulating film by incorporating Si LSI material technology. Furthermore, a ScAlN/GaN HEMT with high polarization and lattice-matching is also promising. An AlN/GaN HEMT on AlN substrate achieves high current density without heating up. Heat dissipation technology is a critical method of improving device performance and efficiency. Moreover, we developed a novel passivation technology to control the electric flux lines using dielectric potions as a new engineering method for controlling the electric field of devices. This paper reports these innovative technologies for RF devices and amplifiers.
A85 EFFICACY AND SAFETY OF DOSE ADJUSTMENT AND DELAYED RESPONSE TO USTEKINUMAB IN MODERATE–SEVERE CROHN’S DISEASE: RESULTS FROM THE IM-UNITI MAINTENANCE STUDY (2018)

Ustekinumab (UST) has been shown to induce and maintain clinical response and remission in moderate-severe Crohn’s disease (CD) in 2 induction (UNITI-1 & 2) and 1 maintenance (IM-UNITI) randomized, PBO-controlled Phase 3 trials. We evaluated the efficacy of UST in 2 additional groups in IM-UNITI: patients (pts) who dose adjusted following loss of response (LOR) and pts who did not have a clinical response to IV UST during induction and had an additional subcutaneous (SC) dose. Pts in clinical response [CR-100] (≥ 100 point decrease in CDAI) after single dose IV dose were randomized to SC PBO, UST 90mg q12w or q8w. Pts who met LOR criteria, defined as a CDAI score of ≥ 220 and a ≥ 100 point increase from the IM-UNITI baseline CDAI score, between wks8 and 32 of IM-UNITI could undergo a single dose adjustment as follows: PBO→q8w, q12w→q8w, and q8w→q8w (no adjustment) and were assessed for CR-100 and clinical remission (CDAI < 150) 16wks later. Separately, UST IV non-responders received SC UST 90mg, then continued SC UST 90mg q8w if in CR 8wks later. 51 (39%), 29 (23%), and 28 (22%) pts in the PBO, q12w and q8w groups, respectively, underwent dose adjustment after meeting LOR criteria. Among these pts, clinical remission and CR-100 were observed in 39% and 71% of pts adjusting PBO→q8w (a situation similar to a drug holiday), 41% and 55% in the q12w→q8w group, and 32% and 46% in the q8w→q8w group when assessed 16wks later (Table 1). Median change in CDAI after adjustment was -121, -141 and -78.5 in the PBO→q8w, q12w→q8w and q8w→q8w groups, respectively. Of 467 pts not in response to UST following IV induction in UNITI1&2, 50.5% and 28.9% were in clinical response and remission 8wks after one additional UST dose (90mg SC). Among the 251 of these pts continuing dosing at wk8 of maintenance, 68.1% were in CR-100 and 50.2% were in remission at wk44. No increases or changes in patterns of adverse events were seen among pts who dose adjusted. In pts who met LOR criteria, dose adjustment from UST 90mg q12w to 90mg q8w provided some additional clinical benefit compared to pts who remained on UST 90mg q8w. Additionally, pts who were initial induction non-responders can benefit from continued treatment with at least 1 SC UST dose 8wks after IV induction. Table 1: Proportion of pts achieving clinical response & remission 16 wks after dose adjustment Table 1: Proportion of pts achieving clinical response & remission 16 wks after dose adjustment Janssen Research & Development, LLC
3GPP LTE Random Access Channel Self-Optimization (2014)

This paper addresses self-optimization of the random access channel (RACH) in the Third-Generation Partnership Project (3GPP) Long-Term Evolution (LTE). Ensuring satisfactory random access (RA) performance in terms of access delay (AD) is crucial for reducing the delays associated with initial access and handovers. The feasibility of self-optimization is investigated by means of simulations, where the coupling between several parameters and the RACH performance in terms of AD is provided. We present two candidate feedback control algorithms that automatically adjust key RACH parameters to meet specified AD targets.
Design of radio frequency polyphase filter and its application in low-IF receivers for large image rejection (2007)

Polyphase filters are an efficient solution for high image rejection and great accuracy quadrature generation in radio frequency (RF) receivers. Analytical modeling of passive polyphase filter suitable for RF front-end applications operating in 2.4 GHz frequency band is dealt with. This analytical analysis has been used to calibrate the optimal values of passive components in order to obtain the maximum image rejection ratio (IRR). Component sizing as well as a judicious placement of the basic cell composing the filter has been taken into account during the layout process. Multi-stage RC network has been implemented in 0.13 mum STMicroelectronics CMOS technology.
Quantitative Analysis of Pulmonary Emphysema Using Local Binary Patterns (2010)

We aim at improving quantitative measures of emphysema in computed tomography (CT) images of the lungs. Current standard measures, such as the relative area of emphysema (RA), rely on a single intensity threshold on individual pixels, thus ignoring any interrelations between pixels. Texture analysis allows for a much richer representation that also takes the local structure around pixels into account. This paper presents a texture classification-based system for emphysema quantification in CT images. Measures of emphysema severity are obtained by fusing pixel posterior probabilities output by a classifier. Local binary patterns (LBP) are used as texture features, and joint LBP and intensity histograms are used for characterizing regions of interest (ROIs). Classification is then performed using a <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">k</i> nearest neighbor classifier with a histogram dissimilarity measure as distance. A 95.2% classification accuracy was achieved on a set of 168 manually annotated ROIs, comprising the three classes: normal tissue, centrilobular emphysema, and paraseptal emphysema. The measured emphysema severity was in good agreement with a pulmonary function test (PFT) achieving correlation coefficients of up to | <i xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">r</i> | = 0.79 in 39 subjects. The results were compared to RA and to a Gaussian filter bank, and the texture-based measures correlated significantly better with PFT than did RA.
A new methodology for investigating airbag-induced skin abrasions (2005)

Although airbags have been shown to reduce the incidence of life-threatening injuries, they have increased the risk of minor injuries such as those to the skin. Based on the distribution of injuries that can be directly attributed to the airbag itself, it is believed that shear loading exists as a mechanism for these skin injuries. The purpose of this study was to develop a new methodology designed to assess the injury potential from different types of airbag with respect to shear loading. This new methodology utilized a high-speed impactor to accelerate the airbag fabric past a sample of skin. Contact normal forces were monitored by the use of pressure sensors, and fabric velocity was determined from a high-speed video. The abraded skin samples were analysed using light microscopic analysis and ultraviolet light source photography. A new abrasion rating method was developed called the total abrasion score, which allows for quantifiable differentiation between the abrasions caused by different airbag fabric and seam types.
Copeptin levels and kidney function in ADPKD: case-control study (2016)

Copeptin levels seem to be strongly correlated with renal function rather than the presence of ADPKD. Further prospective studies need to evaluate its role as a prognostic marker in the early stage of CKD for ADPKD progression.
Automatic 2D-to-3D image conversion using 3D examples from the internet (2012)

The availability of 3D hardware has so far outpaced the production of 3D content. Although to date many methods have been proposed to convert 2D images to 3D stereopairs, the most successful ones involve human operators and, therefore, are time-consuming and costly, while the fully-automatic ones have not yet achieved the same level of quality. This subpar performance is due to the fact that automatic methods usually rely on assumptions about the captured 3D scene that are often violated in practice. In this paper, we explore a radically different approach inspired by our work on saliency detection in images. Instead of relying on a deterministic scene model for the input 2D image, we propose to "learn" the model from a large dictionary of stereopairs, such as YouTube 3D. Our new approach is built upon a key observation and an assumption. The key observation is that among millions of stereopairs available on-line, there likely exist many stereopairs whose 3D content matches that of the 2D input (query). We assume that two stereopairs whose left images are photometrically similar are likely to have similar disparity fields. Our approach first finds a number of on-line stereopairs whose left image is a close photometric match to the 2D query and then extracts depth information from these stereopairs. Since disparities for the selected stereopairs differ due to differences in underlying image content, level of noise, distortions, etc., we combine them by using the median. We apply the resulting median disparity field to the 2D query to obtain the corresponding right image, while handling occlusions and newly-exposed areas in the usual way. We have applied our method in two scenarios. First, we used YouTube 3D videos in search of the most similar frames. Then, we repeated the experiments on a small, but carefully-selected, dictionary of stereopairs closely matching the query. This, to a degree, emulates the results one would expect from the use of an extremely large 3D repository. While far from perfect, the presented results demonstrate that on-line repositories of 3D content can be used for effective 2D-to-3D image conversion. With the continuously increasing amount of 3D data on-line and with the rapidly growing computing power in the cloud, the proposed framework seems a promising alternative to operator-assisted 2D-to-3D conversion.
Driving factors for bioclogging of pores and porous media (2020)

&amp;lt;p&amp;gt;Understanding the interplay between hydrodynamics and biogeochemical processes is of growing importance in environmental applications and studies, especially in the fields of bioremediation and ecology. The majority of the microbial communities living in soil have a surface-attached lifestyle, allowing them to form biofilms. The biofilm growth influences pore geometries by clogging them and thus redirecting the flow, which in return affects biofilm development and local mass transport. After initially clogging single pores, the biofilm structure expands to larger clusters before eventually clogging the porous medium entirely. We study these processes with a soil-born microorganism, &amp;lt;em&amp;gt;Bacillus subtilis&amp;lt;/em&amp;gt;, in microfluidic devices mimicking porous media to get a mechanistic understanding of the driving factors of bioclogging of porous media on different scales.&amp;lt;/p&amp;gt; &amp;lt;p&amp;gt;Carefully designed porous geometries were used for the experiments to study biofilm growth under different flow conditions. After being seeded with bacteria, devices were exposed to a continuous nutrient flow during several days. Continuously monitoring the pressure evaluation and imaging the biofilm growth using Brightfield microscopy allowed a high temporal resolution of biofilm growth processes.&amp;lt;/p&amp;gt; &amp;lt;p&amp;gt;An interplay of hydraulic parameters and geometric features of the porous medium as well as the mass flow rate of nutrients drive the speed of pore clogging. Besides the pore scale clogging, the initiation of biofilm formation as well as the speed of clogging of the entire medium are influenced by the before mentioned parameters. Furthermore, the size and number of the biofilm clusters formed seem to drive the medium scale clogging. This leads to inverting trends concerning the clogging rate in one pore when compared to the porous medium scale for different pore sizes. These results shed light on the pore-scale mechanism as well as driving parameters of biofilm formation and bioclogging and their transferability to the next larger scale, e.g. a porous medium.&amp;lt;/p&amp;gt;
HSiCl3-Mediated Reduction of Nitro-Derivatives to Amines: Is Tertiary Amine-Stabilized SiCl2 the Actual Reducing Species? (2016)

The mechanism of a recently reported, highly chemoselective metal-free protocol of wide general applicability for the reduction of aromatic and aliphatic nitro-derivatives to amines has been investigated. The reaction is supposed to occur through the generation of a Si(II) reducing species; quantum mechanical calculations, and spectroscopic and experimental data strongly suggest the tertiary amine-stabilized dichlorosilylene to be the most probable reducing agent.
Cladding-Pumped Yb-Doped Solid Photonic Bandgap Fiber for ASE Suppression in Shorter Wavelength Region (2008)

We demonstrate suppression of amplified spontaneous emission at 1030 nm in a cladding-pumped ytterbium-doped solid photonic bandgap fiber. This fiber should play an important role for a high power fiber laser lasing around 1180 nm.
Epitaxial Growth of DNA-Assembled Nanoparticle Superlattices on Patterned Substrates* (2020)

1144DNA-functionalized nanoparticles, including plasmonic nanoparticles, can be assembled into a wide range of crystalline arrays via synthetically programmable DNA hybridization interactions. Here we demonstrate that such assemblies can be grown epitaxially on lithographically patterned templates, eliminating grain boundaries and enabling fine control over orientation and size of assemblies up to thousands of square micrometers. We also demonstrate that this epitaxial growth allows for orientational control, systematic introduction of strain, and designed defects, which extend the range of structures that can be made using superlattice assembly. Ultimately, this will open the door to integrating self-assembled plasmonic nanoparticle materials into on-chip optical or optoelectronic platforms.
Cigarette smoking, oral moist snuff use and glucose intolerance (2000)

These results indicate that heavy users of cigarettes or moist snuff have an increased risk of type 2 diabetes. The results could suggest that tobacco use is associated with a low insulin response.
Reliable doping technique for WSe<inf>2</inf> by W:Ta co-sputtering process (2016)

The electrical and material properties of WSe <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> doped by W:Ta co-sputtering process were examined. High acceptor doping concentration (6×10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">13</sup> cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">−2</sup> ) and good effective hole mobility (16.5cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> /Vs) were realized. As a result, low sheet resistance (17kΩ/sq) and contact resistance with Pd metal (11.4kΩ-µm) were measured using TLM structures.
New Design for Compact Color Screen Sets for High-End Digital Color Press (2019)

Digital halftoning is an essential part of the process for printing color, continuous-tone content. Traditionally, the highest quality has been achieved with analog, offset lithographic presses, using color screen sets that yield periodic, clustereddot halftone patterns. Increasingly, these systems are being supplanted by digital presses that are based on either electrophotographic or inkjet marking processes. Due to the inherent instability of the electrophotographic marking process, periodic, clustered-dot halftone patterns are also widely used with such presses. However, digital presses have much lower resolution than their analog counterparts. Simply mimicking the traditional screen designs used with commercial, offset presses will result in halftone patterns that are more susceptible to moire due to the interaction between the periodic patterns used to render the different color channels. This causes instability in the printed colors. The moire can be reduced by increasing the frequency of the halftone patterns. But this may make the print appear grainier than its analog counterpart. In this paper, we introduce a principled design procedure that allows one to design color screen sets that generate periodic, clustered-dot halftone patterns that improve color stability without increasing graininess. We present experimental results to support the benefits of our new color screen set design framework.
Cavitation-threshold Determination and Rheological-parameters Estimation of Albumin-stabilized Nanobubbles (2018)

Nanobubbles (NBs) are of high interest for ultrasound (US) imaging as contrast agents and therapy as cavitation nuclei. Because of their instability (Laplace pressure bubble catastrophe) and low sensitivity to US, reducing the size of commonly used microbubbles to submicron-size is not trivial. We introduce stabilized NBs in the 100-250-nm size range, manufactured by agitating human serum albumin and perfluoro-propane. These NBs were exposed to 3.34- and 5.39-MHz US, and their sensitivity to US was proven by detecting inertial cavitation. The cavitation-threshold information was used to run a numerical parametric study based on a modified Rayleigh-Plesset equation (with a Newtonian rheology model). The determined values of surface tension ranged from 0 N/m to 0.06 N/m. The corresponding values of dilatational viscosity ranged from 5.10<sup>-10</sup> Ns/m to 1.10<sup>-9</sup> Ns/m. These parameters were reported to be 0.6 N/m and 1.10<sup>-8</sup> Ns/m for the reference microbubble contrast agent. This result suggests the possibility of using albumin as a stabilizer for the nanobubbles that could be maintained in circulation and presenting satisfying US sensitivity, even in the 3-5-MHz range.
Gaussian Stochastic Process Modeling of Blend Repaired Airfoil Modal Response Using Reduced Basis Mode Shape Approach (2021)

Abstract A machine learning (ML) approach is developed to predict the effect of blend repairs on airfoil frequency, modal assurance criterion (MAC), and modal displacement vectors. The method is demonstrated on a transonic research rig compressor rotor airfoil. A parametric definition of blend geometry is developed and shown to be capable of encompassing a large range of blend geometry. This blend repair geometry is used to modify the airfoil surface definition and a mesh morphing process transforms the nominal finite element model (FEM) to the repaired configuration. A multi-level full factorial sampling of the blend repair design space provides training data to a Guassian stochastic process (GSP) regressor. The frequency and MAC results create a vector of training data for GSP calibration, but the airfoil mode shapes require further mathematical manipulation to avoid creating GSP models for each nodal displacement. This paper develops a method to significantly reduce blended airfoil mode shape emulation cost by transforming the mode shape training data into a reduced basis space using principal component analysis (PCA). The coefficients of this reduced basis are used to train a GSP that can then predict the values for new blended airfoils. The emulated coefficients are used with the reduced basis vectors in a reconstruction of blended airfoil mode shape. Validation data is computed at a full-factorial design that maximizes the distance from training points. It is found that large variations in modal properties from large blend repairs can be accurately emulated with a reasonable number of training points. The reduced basis approach of mode shape variation is shown to more accurately predict MAC variation when compared to direct MAC emulation. The added benefit of having the full modal displacement field also allows determination of other influences such as tip-timing limits and modal force values.
ChemInform Abstract: Large Scale Preparation of (2S,3S)‐N‐Boc‐3‐Amino‐1,2‐epoxy‐4‐ phenylbutane: A Key Building Block for HIV‐Protease Inhibitors. (1995)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Optical Feedback Height Control System Using Laser Diode Sensor for Near-Field Data Storage Applications (2007)

We demonstrated a laser diode position sensor for a near-field height control system. The feedback signal of the laser diode sensor that resulted from self-mixing interferometry was characterized and modeled by a simplified method. Due to the fine spatial resolution of the laser sensor, an active height control system with nanoscale position precision was designed and realized under a spinning disk for near-field applications.
ChemInform Abstract: Preferred Conformation of C‐Glycosides. Part 12. Synthesis and Conformational Analysis of α,α‐, α,β‐, and . beta.,β‐C‐Trehaloses (1994)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Isolation of Jahanene and Jahanane, and Total Synthesis of the Jahanyne Family (2018)

Two new jahanyne analogues, jahanene and jahanane, highly N-methylated lipopeptides, were isolated from a marine cyanobacterium Okeania sp., and their structures were determined by NMR and MS. In addition, we achieved total syntheses of the jahanyne family and assessed their activities. The resulting growth-inhibitory activity of jahanyne was nearly one-tenth of the previously reported activity. Furthermore, we found that the degree of unsaturation at the terminus of the fatty acid moiety affected the growth-inhibitory activity against human cancer cells.
μ Heavy‐Chain Disease—A Defect in Immunoglobulin Assembly Structural Studies of the χ Chain (1976)

Mu-chain protein GLI is a pentameric molecule with an amino-terminal deletion comprising 130 residues. The half-cysteine residue (position 140) which forms the H-L disulfide bridge in normal IgM is present. Instead of being joined to the L chain, it presumably exists as an additional inter-H-H disulfide bridge. The kappa Bence Jones protein is of normal size and present in two forms: as monomers and dimers. The carboxy-terminal half-cysteine of the monomer is bound to cysteine. Possible reasons for failure of assembly between mu and L chains are briefly discussed.