gebhart/patrepeval huggingface dataset:
Role of mGlu5 Receptors and Inhibitory Neurotransmission in M1 Dependent Muscarinic LTD in the Prefrontal Cortex: Implications in Schizophrenia (2017)

Selective potentiation of the mGlu<sub>5</sub> subtype of metabotropic glutamate (mGlu) receptor using positive allosteric modulators (PAMs) has robust cognition-enhancing effects in rodent models that are relevant for schizophrenia. Until recently, these effects were thought to be due to potentiation of mGlu<sub>5</sub>-induced modulation of NMDA receptor (NMDAR) currents and NMDAR-dependent synaptic plasticity. However, "biased" mGlu<sub>5</sub> PAMs that do not potentiate mGlu<sub>5</sub> effects on NMDAR currents show efficacy that is similar to that of prototypical mGlu<sub>5</sub> PAMs, suggesting that NMDAR-independent mechanisms must be involved in these actions. We now report that synaptic activation of mGlu<sub>5</sub> is required for a form of long-term depression (mLTD) in mouse prefrontal cortex (PFC) that is induced by activation of M<sub>1</sub> muscarinic acetylcholine (mAChR) receptors, which was previously thought to be independent of mGlu<sub>5</sub> activation. Interestingly, a biased mGlu<sub>5</sub> PAM, VU0409551, that does not potentiate mGlu<sub>5</sub> modulation of NMDAR currents, potentiated induction of mLTD. Furthermore, coactivation of mGlu<sub>5</sub> and M<sub>1</sub> receptors increased GABA<sub>A</sub>-dependent inhibitory tone in the PFC pyramidal neurons, which likely contributes to the observed mLTD. Finally, systemic administration of the biased mGlu<sub>5</sub> PAM reversed deficits in mLTD and associated cognitive deficits in a model of cortical disruption caused by repeated phencyclidine exposure that is relevant for schizophrenia and was previously shown to be responsive to selective M<sub>1</sub> muscarinic receptor PAMs. These studies provide exciting new insights into a novel mechanism by which mGlu<sub>5</sub> PAMs can reverse deficits in PFC function and cognition that is independent of modulation of NMDAR currents.
Approach Paper: Evaluation of the Bank's Support for Gender and Diversity (2017)

The objective of the evaluation will be to assess how well and to what extent the Bank’s activities to date have promoted gender equality, women’s empowerment, and development with identity. The evaluation will focus on three key aspects: (i) the relevance of the Bank’s approach to promoting gender equality, women’s empowerment, and development with identity; (ii) the effectiveness to date of operations that seek to support gender equality, women’s empowerment, and development with identity; and (iii) the institutional factors that influence direct investment and mainstreaming in Bank activities. Findings will seek to identify factors that affect the success of various types of operations in different contexts, and to provide recommendations on how the Bank can enhance its support for gender and diversity.
Implementation of an All-digital Receiver for WDM/SCM-PON Subscriber Networks (2007)

Wavelength division multiplexing/sub-carrier multiplexing-passive optical network (WDM/SCM-PON) is the most flexible and cost-effective technique to transmit multimedia signals with varied formats and speeds. In this paper we propose an all-digital receiver structure supporting up to high bit rate of 120 Mbps for a WDM/SCM-PON subscriber network. The proposed receiver is implemented on a single-chip FPGA and its performance is verified by experimental results.
80 km IM-DD transmission for 100 Gb/s per lane enabled by DMT and nonlinearity management (2014)

117Gb/s single wavelength and polarization IM-DD transmission over 40km SMF is first enabled by DMT. With an SOA, 101Gb/s over 80km is demonstrated. The nonlinearity management through parameter optimization and digital compensation is discussed.
Preparation of magnesium ferrite by a malic acid complex (2014)

Nanopowder of MgFe2O4 was prepared from an organic acid complex method. Among three kinds of organic acids examined, it was found from an XRD measurement that the highest purity powder of MgFe2O4 was obtained from a malic acid complex. SEM observation revealed that the powder is fluffy aggregates and each particle has irregular shape. The TG–DTA and IR measurements show that thermolysis process of a malic acid complex in air was mainly constructed at two stages consisting of dehydration and ligand pyrolysis. Furthermore, it was confirmed from a VSM measurement that the saturation magnetization of MgFe2O4 nanopowder is much smaller value than that of the bulk material.
Channel List Selection Based on Quality Prediction in WirelessHART Networks (2018)

WirelessHART is one of the most widely used technologies in industrial wireless networks. However, its performance is highly influenced by the quality of wireless channels. To improve the reliability of wireless communications, WirelessHART employs channel blacklisting and channel hopping mechanisms, which highlights the importance of channel assessment. Traditional methods generally resort to packet reception ratio (PRR) of the previous time slot to assess and allocate channels, but this is not accurate. In this paper, we propose a learning-based framework for predicting the PRR, and on the basis of the predicted PRR, we develop a heuristic channel selection algorithm to confirm the channel list, which takes into account the balance of channel diversity and route diversity. Simulation results demonstrate that our algorithm outperforms existing ones in terms of achieved reliability.
Network loss inference with second order statistics of end-to-end flows (2007)

We address the problem of calculating link loss rates from end-to-end measurements. Contrary to existing works that use only the average end-to-end loss rates or strict temporal correlations between probes, we exploit second-order moments of end-to-end flows. We first prove that the variances of link loss rates can be uniquely calculated from the covariances of the measured end-to-end loss rates in any realistic topology. After calculating the link variances, we remove the un-congested links with small variances from the first-order moment equations to obtain a full rank linear system of equations, from which we can calculate precisely the loss rates of the remaining congested links. This operation is possible because losses due to congestion occur in bursts and hence the loss rates of congested links have high variances. On the contrary, most links on the Internet are un-congested, and hence the averages and variances of their loss rates are virtually zero. Our proposed solution uses only regular unicast probes and thus is applicable in today's Internet. It is accurate and scalable, as shown in our simulations and experiments on PlanetLab.
Erratum: “Enhanced photoluminescence of InAs self-assembled quantum dots grown by molecular-beam epitaxy using a “nucleation-augmented” method” [Appl. Phys. Lett. 85, 567 (2004)] (2005)

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Structure and Reactivity of a Cobalt(I) Phthalaldehyde Complex with Both σ- and π-Bonded Aldehyde Groups (1999)

A bidentate phthalaldehyde ligand with both σ and π coordination of the aldehyde groups is found in [(C<sub>5</sub> Me<sub>5</sub> )Co{(C(O)H)<sub>2</sub> C<sub>6</sub> H<sub>4</sub> }] (structure depicted). This complex is the "resting state" of the catalyst in the ring closure of the dialdehyde to give the lactone. Interchange of coordination modes occurs with a barrier of 70 kJ mol<sup>-1</sup> at 35°C. Investigation of other Co<sup>I</sup> chelate complexes with a single aldehyde group shows that the coordination mode of the aldehyde is dictated by the nature of the bonding of the other ligating group.
Respiratory syncytial virus‐induced exaggeration of allergic airway disease is dependent upon CCR1‐associated immune responses (2004)

Severe respiratory syncytial virus (RSV) infection has a significant impact on airway function, and may alter subsequent development of asthma. CCR1 mRNA was significantly up-regulated during primary RSV infection in BALB/c mice, and was also up-regulated during allergen exposure in sensitized mice. Although CCR1(-/-) mice exhibited similar levels of airway hyperresponsiveness (AHR) as wild-type mice in response to cockroach allergen alone, in animals treated with RSV prior to cockroach antigen (CRA) sensitization and challenge, a significant decrease in exacerbated AHR was observed in the CCR1(-/-) mice. The reduction in AHR after RSV and allergen challenge in CCR1(-/-) mice was not associated with changes in peribronchial eosinophilia, but was accompanied by significantly decreased IL-13 levels in the lungs, as well as an absence of mucus cell staining within the airways. When T lymphocyte numbers were compared in animals receiving CRA to animals receiving a combination of RSV and allergen an increase in both CD4 and CD8 T lymphocytes could be detected in wild-type but not CCR1(-/-) animals. Thus, these data suggest that CCR1-mediated responses have a primary role for inducing severe disease during RSV infection, and may be responsible for altering the lung pathophysiological responses to subsequent allergen challenges via IL-13-mediated mechanisms.
Single bath electrodeposition of CuInSe/sub 2/ and Cu(In,Ga)Se/sub 2/ for thin film photovoltaic cells (2005)

In this paper, an electrodeposition (ED) process for growth of CuInSe/sub 2/ and Cu(In,Ga)Se/sub 2/ films from single baths is presented. The use of buffered baths and careful selection of bath concentrations allows good control of the composition of the deposited films. Prior to cell processing, CuInSe/sub 2/ and Cu(In,Ga)Se/sub 2/ films require recrystallization by annealing in H/sub 2/Se/Ar. Promising results have been obtained for ED CuInSe/sub 2/- and ED Cu(In,Ga)Se/sub 2/-based devices. Optimization of the selenization treatment and a better understanding of the bath chemistry and film growth mechanism are expected to lead to significant improvements in cell performance.
Fluxless Sn-3.5 mass%Ag Solder Bump Flip Chip Bonding by Ultrasonic Wave (2002)

The ultrasonic solder bump flip chip bonding was investigated as a method of fluxless bonding. The 100 \\micron-diameter Sn–3.5 mass%Ag solder bumps were formed at 12 positions on a test Si-die by laser ball bonding process. The test flip chip dies were bonded to a TSM-coated glass substrate on a hotplate at different bonding loads and ultrasonic power condition. The die shear strength was evaluated and fracture surfaces were examined with SEM. The Sn–Ag solder flip chip bonding was possible at lower temperature than the melting point of Sn–3.5Ag solder. The die shear strength increased with increasing bonding temperature, bonding load, and ultrasonic power. However, at excessive bonding load condition over 0.8 N/bump, the die shear strength decreased. The bump height decreased with increasing bonding load.
Hydrocarbon Fuels from Palm Oil through Hydrolysis Followed by Oxidative Cleavage and Decarboxylation (2019)

Renewable hydrocarbons in the composition ranges of gasoline and diesel were prepared from palm oil through hydrolysis and oxidative cleavage followed by decarboxylation. Hydrolysis was carried out with water in a subcritical state to obtain saturated and unsaturated fatty acids from palm oil triglycerides. The hydrolysis product was treated with KMnO4 as an oxidizing agent to convert unsaturated fatty acids into short fatty acids by cleaving C=C double bonds. The obtained product was then decarboxylated with Pd/C catalyst under N2 pressure to produce hydrocarbons including gasoline and diesel fractions. This work demonstrated the potential of palm oil as a source of renewable fuels, providing about 21 wt% gasoline hydrocarbons and 48 wt% diesel hydrocarbons based on palm oil as the feedstock.
GeO2–SnCoC Composite Anode Material for Lithium-Ion Batteries (2014)

Current methods for extending the cycle life of volume-expanded anode materials for lithium-ion batteries mainly focus on development of nanosize three-dimensional structures and composite materials. We propose a novel anode material of GeO2–Sn30Co30C40 that is synthesized by high energy ball milling (SPEX). This material depends on the nanosized and composite concept, which combines the advantageous properties of Sn–Co–C (long cycle life) and GeO2 (high capacity). The composite anode shows a reversible capacity over 800 mAh/g with good capacity retention. Furthermore, the first-cycle Coulombic efficiency is 80%, much higher than the 34.6% obtained for pure GeO2. Pair distribution function measurements indicated the reversible reaction of GeO2 and SnO2, which is the key factor in the improved Coulombic efficiency. This reversibility can be explained by the catalytic role of Co3Ge2 phase, which facilities the conversion reactions of metal oxides and acts as an electronic conductive component for the composite anode.
3D pose refinement from reflections (2008)

We demonstrate how to exploit reflections for accurate registration of shiny objects: The lighting environment can be retrieved from the reflections under a distant illumination assumption. Since it remains unchanged when the camera or the object of interest moves, this provides powerful additional constraints that can be incorporated into standard pose estimation algorithms. The key idea and main contribution of the paper is therefore to show that the registration should also be performed in the lighting environment space, instead of in the image space only. This lets us recover very accurate pose estimates because the specularities are very sensitive to pose changes. An interesting side result is an accurate estimate of the lighting environment. Furthermore, since the mapping from lighting environment to specularities has no analytical expression for objects represented as 3D meshes, and is not 1-to-1, registering lighting environments is far from trivial. However we propose a general and effective solution. Our approach is demonstrated on both synthetic and real images.
Competing Energy Transfer Pathways in a Five-Chromophore Perylene Array (2018)

A perylene (donor–dimer)–acceptor–(donor–dimer) pentamer array is synthesized to investigate the competition between excimer formation and Förster resonance energy transfer. Using time-resolved fluorescence, we show that, upon excitation, the isolated perylene dimer forms an excimer with a time constant of 4.3 ns. However, in the pentamer array, when either of two constituent dimers donate their energy to the acceptor fluorophore, the excimer energy trap is eliminated. The pentamer macromolecule shows broad absorption and reduced self-absorption, at some cost to fluorescence quantum yield.
Regulation of pain signaling by the innate immune system (2020)

The innate immune system is the body's first response to infections and its activation gives rise to pain. How the innate immune system interacts with the sensory nervous system and contributes to pain is poorly understood. We have shown previously that intraplantar CFA injection leads to an upregulation of the deubiquitinase USP5 in dorsal root ganglia and spinal cord, and this in turn leads to an increase in the numbers of Cav3.2 T-type calcium channels in an activity dependent manner. Blocking USP5 interactions with cell permeant disruptor peptides mediates analgesia. Here we demonstrate that specific Toll-like receptors (TLRs) are up-regulated in response to CFA injection. This leads to macrophage infiltration into the dorsal root ganglia, and the production of interleukin 33 (IL33) which acts on sensory neuron to increase their activity. Block of spinal IL33/ST2 receptor signals attenuates CFA-induced inflammatory pain. The CFA induced upregulation of USP5 is abolished in TLR2 null mice, altogether indicating that the CFA mediated dysregulation of T-type calcium channel activity involves the activation of a TLR2-IL33-ST2 pathway, leading to the development of inflammatory pain.
Sparse IBR Using Range Space Rendering (2003)

In this paper, we propose a new solution to the sparse image-based rendering (IBR) problem. Given two images taken from different viewpoints, our algorithm can accurately generate images from new viewpoints in between the original two views. This paper contributes to the sparse IBR in the following aspects: (1) Direct range space matching and multiple depth maps rendering. (2) Good rendering can be achieved with incorrect depth values, especially those textureless regions.(3) An efficient coarse-to-fine strategy to accelerate rendering and avoid problems caused by repetitive patterns. (4) A weak scene consistency constraint to simultaneously refine the rendering results and detect the occlusions. The proposed algorithm has been implemented and tested on real images and promising experimental results are demonstrated in the paper.
The Palantir Grid Meta-Information System (2006)

Grids allow large scale resource-sharing across different administrative domains. Those diverse resources are likely to join or quit the grid at any moment or possibly to break down. Grid monitoring tools have to adapt supporting access information to these heterogeneous and not reliable environments. There is a wide rage of types of resources to be monitored, with different nature, characteristics and so on. For instance grid users want to monitor from which is the state of the jobs that submit till how many processors has a given resources of a given centre. These issues make the task of monitoring complex to treat, and it is difficult to provide a generals ways for accessing to all this information. In this work we propose a set of functionalities that a grid information system should provide. We describe the Palantir meta-information system that has been designed for uniform the access to different monitoring and information systems and that implements all the discussed functionalities. This meta-information system tries to abstract the resource information that underlies on the local systems, and homogenize the access to all this. We present the architecture of Palantir and its main characteristics
Increased hydrogen peroxide impairs angiotensin II contractions of afferent arterioles in mice after renal ischaemia–reperfusion injury (2016)

Renal IRI in mice selectively impairs afferent arteriolar responses to Ang II because of H2 O2 accumulation that is caused by a reduced catalase activity. This could serve to buffer the effect of Ang II after IRI and may be a protective mechanism.
419. Kinetics of the reaction of alkyl and aryl compounds of the nickel group with pyridine (1961)

F. Basolo, J. Chatt, H. B. Gray, R. G. Pearson and B. L. Shaw, J. Chem. Soc., 1961, 2207 DOI: 10.1039/JR9610002207
Optical design of a dynamic focus catheter for high-resolution endoscopic optical coherence tomography (2008)

The optical system design of a dynamic focus endoscopic probe for optical coherence tomography is reported. The dynamic focus capability is based on a liquid lens technology that provides variable focus by changing its curvatures in response to an electric field variation. The effects of a cylindrical exit window present, in practice, for a catheter were accounted for. Degradation in image quality caused by this window was corrected to get diffraction limited imaging performance. As a result, the dynamically focusing catheter with a lateral resolution ranging from 4 to 6 mum through an approximately 5 mm imaging distance was designed without mechanically refocusing the system.
ChemInform Abstract: New Approach to AI‐77B: Stereoselective Construction of a Potential Precursor of the Amino Acid Side Chain. (1997)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Anisotropic electron mobility studies on Cl2-NDI single crystals and the role of static and dynamic lattice deformations upon temperature variation (2015)

The anisotropic electron transport in the (001) plane of sublimation-grown Cl$_{2}$-NDI (naphthalene diimide) single crystals is analysed over a temperature range between 175 K and 300 K. Upon cooling from room temperature to 175 K the electron mobility along the direction of preferred transport monotonously increases from 1.5 cm$^{2}$/Vs to 2.8 cm$^{2}$/Vs according to a distinct temperature relation of $~T^{-1.3}$. At first glance, these characteristics allude to a coherent, i.e. band-like charge carrier transport predominantly governed by inelastic scattering with accoustic phonons. However, as we will demonstrate, the experimental mobility data can be consistently described within the framework of incoherent, hopping-type transport modeled by Levich-Jortner rates, explicitly accounting for the inner and outer relaxation energies related to thermally induced lattice effects and enhanced electron-phonon interaction at elevated temperatures. Complementary band-structure calculations yielding temperature dependent effective mass tensors deviate stronger from experimentally observed spatially anisotropic transport behavior. Thus, these results hint at the fact that by the particular interplay of the transport energies the mobility of a given organic semiconducting material might appear to be band-like in a certain temperature regime even though the underlying charge carrier transport can be of incoherent, hopping-type nature. Building on this description, we further explore the role of the intermolecular electronic coupling and develop a procedure to distinguish between its dependence on static and dynamic lattice deformation upon temperature variation.
Simulation and experimental characterization of VC precipitation and recovery stress formation in an FeMnSi-based shape memory alloy (2023)

In this study, TC-PRISMA was employed to simulate the precipitation (number density and radius) of an FeMnSi-based shape memory alloy (FeMnSi-SMA), with a chemical composition of Fe–17Mn–5Si–10Cr–4Ni-1(V, C) (wt%), during one-step and two-step aging processes. In addition, transmission electron microscopy (TEM) was used to study the microstructures of the specimens, particularly the VC precipitates, under several selected two-step aging conditions to validate the simulation results. Furthermore, thermomechanical characterization was conducted to investigate the recovery stress of the FeMnSi-SMA under the selected two-step aging conditions. It was found that, compared to only one-step aging, the first aging at a lower temperature (600 °C) followed by a second aging at a higher temperature (670 °C) can take advantage of both high nucleation rate and high growth rate. This achieves a similar precipitation state in a significantly shorter time (approximately 1/6 of the total duration of the one with one-step aging). The recovery stress value (509 MPa) corresponding to the two-step aging condition (first step: 600 °C for 20 h; second step: 670 °C for 6 h) shows a similar stress value range (514 MPa) corresponding to the one-step aging condition (600 °C for 144 h); however, the fracture strain is 40% higher. The number density and VC radii simulated by TC-PRISMA are generally consistent with the TEM observations.