gebhart/patrepeval huggingface dataset:
Search for gluino mediated bottom- and top-squark production in multijet final states in pp collisions at 8 TeV (2013)

A search for supersymmetry is presented based on events with large missing transverse energy, no isolated electron or muon, and at least three jets with one or more identified as a bottom-quark jet. A simultaneous examination is performed of the numbers of events in exclusive bins of the scalar sum of jet transverse momentum values, missing transverse energy, and bottom-quark jet multiplicity. The sample, corresponding to an integrated luminosity of 19.4 fb -1 , consists of proton-proton collision data recorded at a center-of-mass energy of 8 TeV with the CMS detector at the LHC in 2012. The observed numbers of events are found to be consistent with the standard model expectation, which is evaluated with control samples in data. The results are interpreted in the context of two simplified supersymmetric scenarios in which gluino pair production is followed by the decay of each gluino to an undetected lightest supersymmetric particle and either a bottom or top quark-antiquark pair, characteristic of gluino mediated bottom-or top-squark production. Using the production cross section calculated to next-to-leading-order plus next-to-leading-logarithm accuracy, and in the limit of a massless lightest supersymmetric particle, we exclude gluinos with masses below 1170 GeV and 1020 GeV for the two scenarios, respectively.
Multi‐source ambient energy harvester based on RF and thermal energy: Design, testing, and IoT application (2020)

Abstract Billions of wireless sensing devices must be powered for IoT applications. Collecting energy from the ambient environment to power sensor nodes is a promising solution. Solar energy has been one of the main sources of ambient energy due to its availability, higher power density, and the maturity of the solar photovoltaic industry. However, there are many scenarios (indoor environment, outdoor environment during nighttime, poor weather conditions, underground, etc) where ambient solar energy is either not available or not sufficient for practical applications. For such scenarios, other renewable sources of energy must be sought. Typically, not enough power is collected from one ambient source to charge sensor nodes for continuous operation. In this work, we present a multi‐source energy harvester that collects RF and thermal energy (both available 24 hours) from the ambient environment simultaneously. The RF energy harvester is multi‐band and collects power from GSM (900, 1800 MHz) and 3G (2100 MHz). The thermal harvester converts diurnal temperature fluctuations to electrical energy using high thermal effusivity phase change material. Extensive field testing has been performed in three different conditions—outdoors, indoors, and buried underground—to highlight the usefulness of the multi‐source energy harvester in all these environments. When one source is disabled, the harvester still generates energy from the remaining active source and can enable continuous operation of futuristic IoT sensors. As a proof of concept, a real‐world IoT application is demonstrated, where temperature and humidity sensors are powered by the multi‐source energy harvester. Continuous robust operation of the sensors and wireless data transmission after each 3.7 seconds are expected when both harvesters operate in full mode. Scenarios, where only single thermal energy harvester or only single RF energy harvester operates, are also demonstrated and data transmission with average time intervals of 30 seconds and 9 minutes is achieved, respectively.
Stacked double-layer nanomembrane Fano modulators (2016)

We report a novel bi-layer photonic crystal slab (PCS) Fano modulator via a coupled double-layer Si nanomembrane (SiNM) capacitor like structure. Surface normal incident light intensity modulation near 1500nm was achieved by carrier accumulation induced resonance spectral shifting. Device performance simulation suggests the opportunity for high speed modulation exceeding GHz with 20&mu;m &times; 20&mu;m device size.
Iterative learning control of electromechanical camless valve actuator (2001)

In this paper we consider the control of the valve trajectory in a gasoline engine equipped with an electromechanical camless valvetrain (EMCV) actuator. Precise control of the voltage applied to the coils is required to avoid high contact velocities during valve closing and opening, i.e., to ensure soft landing. In our previous work we designed a tracking controller that consists of a constant preset voltage augmented by a voltage command based on a linear feedback and modified by an Iterative Learning Controller (ILC). The new results reported here involve the preset voltage in the learning process. This yields good results in the presence of unknown gas flow forces through the valves. As a consequence, a non-square learning algorithm is used to calculate more input values than available error values. We demonstrate the closed loop performance through simulations with an unknown acting gas flow force that emulates a realistic varying engine load.
Day 2 Transfer in Clinical ART (2012)

Over the past 20 years, numerous techniques have enhanced assisted reproductive technology outcomes to help couples have >60,000 infants in the United States in 2008. Several different days for embryo transfers have been studied, but debate for the best timing of embryo transfer is still ongoing. With growing concern about multiple gestations and neonatal outcomes, early cleavage stage embryo transfer with novel embryo selection tools may be attractive to some patients and in vitro fertilization programs. In this review, we summarize clinical and basic studies relating to the timing of embryo transfer and highlight the possibilities of safe embryo transfer by combining advanced embryo screening tools with potentially high efficiency and low adverse effects on clinical outcome.
An interrater and intrarater reliability study of 3 photographic scales for the classification of perioral aesthetic features. (2014)

All scales demonstrated a high degree of intrarater and interrater reliability during the validation process. Physician concordance was good; subject ratings were reliable and comparable to physician assessments.
Joint Turbo Decoding for Overloaded MIMO-OFDM Systems (2016)

To achieve an excellent error-correcting capability, the Third-Generation Partnership Project (3GPP) Long-Term Evolution (LTE) employs turbo codes as its forward error correction (FEC) standard. In addition, to achieve higher throughput, the LTE also implements multiple-input-multiple-output (MIMO) systems. Although a conventional turbo decoding scheme gives satisfactory performance in ideal MIMO systems, significant performance degradation occurs in an overloaded MIMO system when the number of transmit antennas is larger than that of receive antennas. In this paper, a joint decoding scheme for turbo codes, i.e., so-called joint turbo decoding, is proposed. In joint turbo decoding, calculations of soft information are conducted for each combination of bits from all streams instead of separately between each stream. In addition, to combine the trellis diagrams from all the streams, a super-trellis diagram is employed. The numerical results obtained through computer simulation show that the proposed scheme performs better than the conventional scheme, particularly in the case of an overloaded MIMO system. In the MIMO system with four transmit and two receive antennas, up to 2-dB performance enhancement can be attained at a bit error rate (BER) of 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-5</sup> . The proposed scheme also obtains improved throughput with a throughput/(SNR/stream) ratio close to the theoretical capacity of overloaded MIMO systems.
Mirror-image Streptavidin with Specific Binding to “Non-natural” L-biotin (2022)

Abstract The streptavidin-biotin system is known to have a very high affinity and specificity and is widely used in biochemical immunoassays and diagnostics. However, this method is affected by endogenous D-biotin in serum sample measurements (biotin interference). While several efforts using alternative high-affinity binding systems (e.g., genetically modified streptavidin and biotin derivatives) have been attempted, these efforts have all led to reduction in affinity. To solve this interference issue, the enantiomer of streptavidin was synthesized, which enabled specific binding to L-biotin. We successfully obtained a functional streptavidin molecule by peptide synthesis using D-amino acids and an in vitro refolding technique. Several characterizations, including size exclusion chromatography (SEC), circular dichroism spectra (CD), and heat denaturation experiments collectively confirmed the higher-order enantiomer of natural streptavidin had been formed with comparable stability to the natural protein. Non-natural L-biotin specific binding of this novel molecule enabled us to avoid biotin interference in affinity measurements using the Biacore system and enzyme-linked immunosorbent assay (ELISA). We propose the enantiomer of streptavidin as a potential candidate to replace the natural streptavidin-biotin system, even for in vivo use.
Fragments sur l'Inde et sur le général Lally (2003)

info:eu-repo/semantics/published
A yellow fever–Zika chimeric virus vaccine candidate protects against Zika infection and congenital malformations in mice (2018)

The recent Zika virus (ZIKV) epidemic in the Americas led to an intense search for therapeutics and vaccines. Here we report the engineering of a chimeric virus vaccine candidate (YF-ZIKprM/E) by replacing the antigenic surface glycoproteins and the capsid anchor of YFV-17D with those of a prototypic Asian lineage ZIKV isolate. By intracellular passaging, a variant with adaptive mutations in the E protein was obtained. Unlike YFV-17D, YF-ZIKprM/E replicates poorly in mosquito cells. Also, YF-ZIKprM/E does not cause disease nor mortality in interferon α/β, and γ receptor KO AG129 mice nor following intracranial inoculation of BALB/c pups. A single dose as low as 1 × 10<sup>2</sup> PFU results, as early as 7 days post vaccination, in seroconversion to neutralizing antibodies and confers full protection in AG129 mice against stringent challenge with a lethal inoculum (10<sup>5</sup> LD<sub>50</sub>) of either homologous or heterologous ZIKV strains. Induction of multi-functional CD4<sup>+</sup> and CD8<sup>+</sup> T cell responses against ZIKV structural and YFV-17D non-structural proteins indicates that cellular immunity may also contribute to protection. Vaccine immunogenicity and protection was confirmed in other mouse strains, including after temporal blockade of interferon-receptors in wild-type mice to facilitate ZIKV replication. Vaccination of wild-type NMRI dams with YF-ZIKprM/E results in complete protection of foetuses against brain infections and malformations following a stringent intraplacental challenge with an epidemic ZIKV strain. The particular characteristic of YF-ZIKprM/E in terms of efficacy and its marked attenuation in mice warrants further exploration as a vaccine candidate.
Towards a color prediction model for printed patches (1999)

A novel color prediction model is presented which unifies, within a framework based on matrices, the phenomena of surface reflection, light absorption, diffuse light sources, superposition of multiple ink layers, and others.
Regiocontrolled synthesis of mono-, di-, and trisubstituted cyclohexenones by cycloaddition of vinyl sulfones to 1-methoxy-3-[(trimethylsilyl)oxy]-1,3-butadienes. Conversion of alkenes into effective dienophilic reagents (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRegiocontrolled synthesis of mono-, di-, and trisubstituted cyclohexenones by cycloaddition of vinyl sulfones to 1-methoxy-3-[(trimethylsilyl)oxy]-1,3-butadienes. Conversion of alkenes into effective dienophilic reagentsWilliam A. Kinney, Gary D. Crouse, and Leo A. PaquetteCite this: J. Org. Chem. 1983, 48, 25, 4986–5000Publication Date (Print):December 1, 1983Publication History Published online1 May 2002Published inissue 1 December 1983https://pubs.acs.org/doi/10.1021/jo00173a040https://doi.org/10.1021/jo00173a040research-articleACS PublicationsRequest reuse permissionsArticle Views819Altmetric-Citations60LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Advantage of cocktail-use of two anti-tumor monoclonal antibodies, KM-93 and KM-231, in serum diagnosis of cancer. (1989)

Two mouse monoclonal antibodies (MoAbs), KM-93 raised against human lung adenocarcinoma and KM-231 raised against human gastric cancer, were useful in serum diagnosis of several human cancer. KM-93 and KM-231 recognize sialyl Lex epitope and sialyl Lea epitope, respectively, expressed on glycoprotein and glycolipid. We established a new "cocktail" sandwich enzyme-linked immunosorbent assay system using the two MoAbs and the advantage of this assay system, which can simultaneously detect sialyl Lex and sialyl Lea antigens, is assessed in the present study. The new assay system is composed of a mixture of KM-93 and KM-231 as 1st antibodies and a mixture of biotinylated two MoAbs as 2nd antibodies. We evaluated the concentration of MoAbs and optimized it to gain high cancer-positivity. This assay system covered sialyl Lex positive and/or sialyl Lea-positive sera and gave a high rate of positive results in lung adenocarcinoma (62.3%), gastric cancer (32.5%), colon cancer (37.5%), pancreatic cancer (83.3%), bile duct and gall bladder cancer (66.7%) and hepatoma (76.9%), whereas positive results in healthy adults remained low. Positive results in benign diseases of lung (12.5%), pancreas (10.8%), gall bladder and bile duct (9.1%) were very low, but were higher in liver cirrhosis (33.3%), hepatitis and liver injury (34.8%). Simultaneous detection of two carbohydrate antigens, sialyl Lex and sialyl Lea was clearly superior to single detection.
Release of3H‐Acetylcholine from Isolated Guinea Pig Ileum. A Radiochemical Method for Studying the Release of the Cholinergic Neurotransmitter in the Intestine (1977)

Abstract Innervated strips of longitudinal muscle of guinea pig ileum were incubated with 3 H‐choline in the presence of physostigmine, after which the efflux of tritiated metabolites was studied. Under resting conditions 3 H‐acetylcholine, 3 H‐choline and other tritiated metabolites were released into the incubation medium. Analysis of the kinetics of the release of the metabolites indicated that the release occurred from at least 2 different compartments. Under the unstimulated conditions used, between 72 and 78% of the radioactivity remained in a third, non‐releasable compartment. The release of 3 H‐acetylcholine showed spontaneous fluctuations which were positively correlated to spontaneous variations of the isometric tension of the preparation. Electrical field stimulation at low frequency (0.5 Hz) consistently increased the release of 3 H‐acetylcholine. The release of 3 H‐choline was increased only slightly or not at all by the electrical stimulation. For studying stimulation‐evoked release of 3 H‐acetylcholine, it is suggested that the measurement of the total quaternary amine release is of similar value to measurement of 3 H‐acetylcholine itself. This approach considerably simplified the method. During 5 consecutive stimulation periods of 150 pulses each, the increase in the release of total quaternary amines diminished with time. By taking into account the reduction of the stores of radioactivity in the tissue during the experiment, correction for the negative trend could be made. When the preparation was stimulated with between 30 and 3 000 pulses a close correlation was found between the increase in the release of total quaternary amines and the number of pulses delivered. The volley output of the quaternary amines was not constant, however, but diminished by increasing stimulation frequency.
Cryogenic hydrogen maser (2010)

A new type of atomic hydrogen maser that operates in a dilution refrigerator has been developed. In this device, the hydrogen atoms circulate back and forth between a microwave pumped state invertor in high field and the maser cavity in zero field. A prototype maser with a small maser cavity has been built and the results obtained so far are encouraging. Stable maser oscillations were observed for temperatures of the maser bulb between 230 mK and 660 mK and for densities up to 3 x 1012cm⁻³. The short term frequency stability was measured with the help of two high quality quartz crystal oscillators by the three-cornered-hat method. The observed fractional frequency fluctuations for an averaging time of 1 s were 6.3 ± 3.7 x 10⁻¹⁴, which is lower than the results from the best room temperature masers. In conjunction with the stability measurements, the phase noise of the maser electronics was investigated. In particular, the temperature dependence of the phase noise of the cooled preamplifier was measured and it was shown that anomalous high noise levels between 2.2 K and 4.2 K are caused by the boiling of the liquid helium. From the temperature dependence of the maser frequency, the binding energy E[sub B] of H on ⁴He could be determined to a high precision. The result is E[sub B] = 1.011 ± 0.010 K. An extensive computer simulation program has been written that models the operation of the cryogenic hydrogen maser. It has been used to analyze and interpret some of the data. In addition, this simulation program is helpful for the design of an improved second generation cryogenic maser. Based on the present data and the model calculations, a new pumping scheme is proposed that is expected to increase the efficiency of the state invertor significantly.
Olefin Epoxidation with Inorganic Peroxides. Solutions to Four Long‐Standing Controversies on the Mechanism of Oxygen Transfer (2004)

Abstract For Abstract see ChemInform Abstract in Full Text.
FOCUS :D ESORPTION IONIZATION AND MACROMOLECULAR MS Localization of the Noncovalent Binding Site Between Amyloid--Peptide and Oleuropein Using Electrospray Ionization FT-ICR Mass Spectrometry (2008)

Abnormal accumulation and aggregation of amyloid--peptide (A) eventually lead to the formation and cerebral deposition of amyloid plaques, the major pathological hallmark in Alzheimer’s disease (AD). Oleuropein (OE), an Olea europaea L. derived polyphenol, exhibits a broad range of pharmacological properties, such as antioxidant, anti-inflammatory, and antiatherogenic, which could serve as combative mechanisms against several reported pathways involved in the pathophysiology of AD. The reported noncovalent interaction between A and OE could imply a potential antiamyloidogenic role of the latter on the former via stabilization of its structure and prevention of the adaptation of a toxic -sheet conformation. The established -sheet conformation of the A hydrophobic carboxy-terminal region and the dependence of its toxicity and aggregational propensity on its secondary structure make the determination of the binding site between A and OE highly important for assessing the role of the interaction. In this study, two different proteolytic digestion protocols, in conjunction with high-sensitivity electrospray ionization mass spectrometric analysis of the resulting peptide fragments, were used to determine the noncovalent binding site of OE on A and revealed the critical regions for the interaction. (J Am Soc Mass Spectrom 2008, 19, 1078 –1085) © 2008 American Society for Mass Spectrometry
SayMore: Language documentation productivity (2013)

Language Documenters quickly amass a large number of original recordings and artifacts based on them. We need to manage recordings, document informed consent, transcribe, translate, enter metadata, convert file formats, and, finally, submit to a digital archive. Along the way, we need to keep all these files well-organized and labeled. And we must keep track of the goals of the project in order to emerge with the desired coverage in areas such as genre, spontaneity, and the social roles of the speaker. We have powerful software for parts of this workflow, including Arbil, Elan, and EXMARaLDA. However, many of these tools appear best-suited for rather computer-savvy linguists, or those who can attend training courses. Recent linguistic software including WeSay (Albright and Author 2007) and FOLKER (Schmidt and Schütte 2010) have demonstrated that we can involve a wider spectrum of participants by using software with a task-focused interface that prioritizes clarity and efficiency over flexibility. In compensation, such software needs to emit data files that can be opened in more complex/powerful applications for further work. This paper presents SayMore (http://saymore.palaso.org), a new software tool that streamlines the collection and annotations of recordings. Currently, SayMore eases the collecting of media files from a recording device, the addition of metadata, transcription, and, perhaps uniquely, oral annotation (respeaking and translation). All time-aligned data is stored in ELAN XML format, so that projects needing to go beyond SayMore’s built-in annotation capability can do so easily. For interlinearization, SayMore can export to FLEx, Toolbox, and other formats. For sharing with the community, SayMore produces subtitled videos. For archiving, it has built-in capability to convert file formats to those appropriate for long-term accessibility. Finally, the paper describes how SayMore helps researchers monitor progress towards project goals along several axes, including genre, spontaneity, and which workflow steps have been completed.
Constant-Envelope Precoding for Satellite Systems (2020)

In this paper, Constant-Envelope Precoding techniques are presented for satellite-based communication systems. In the developed transmission technique the signals of the antennas are designed to be of constant amplitude, improving the robustness of the latter to the nonlinear distortions on satellite systems, introduced by the employed on-board Traveling-Wave-Tube-Amplifiers. We consider the forward link of a multi-beam broadband satellite system where the aim is to design the signals at the gateway such that the desired symbols are transmitted to the intended user terminals and the transmitted signals from the satellite terminal are of constant amplitude. At first, the gateway signals are designed given that a fixed on-board beamformer is applied to the satellite terminal. Then, the case of an adaptive on-board beamformer is considered which is designed jointly with the gateway signals. The design of the gateway signals and the adaptive on-board beamformer, in the second case, requires solving difficult nonconvex problems. Efficient algorithmic solutions are developed based on the saddle point method. The effectiveness of the proposed approaches is verified via numerical results.