gebhart/patrepeval huggingface dataset:
A different approach to a highly efficient wireless energy harvesting device for low-power application (2013)

This paper presents a different approach for a highly efficient Wireless Energy Harvesting (WEH) device design at 2.45 GHz for low-power density (μW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> ) applications. Therefore, the high-efficiency rectifier was designed, in order to evaluate its harvesting performances; the rectifier was connected to a classical antenna and the energy harvesting characterization was performed. A correct model of a Schottky diode is necessary despite the nonlinear behavior. To increase the conversion efficiency an electromagnetic resonant phenomenon is proposed. To validate this method, we developed a rectifier circuit capable of recovering signals at 2.45 GHz with a high RF-DC efficiency conversion. For a low-power density of 1.3 μW/cm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , the rectifier presents a maximum conversion efficiency of 70% and when connected to an antenna of 43%.
Chapter 20. A Continuum Multiphysics Theory for Electroactive Polymers and Ionic Polymer Metal Composites (2015)

The existence of a theoretical continuum multiphysics infrastructure for modeling the behavior of electroactive polymers and ionic polymer metal composites is essential for the design, material qualification and material certification for sensing, actuation and energy harvesting applications. The present chapter summarizes a continuum multiphysics methodology for modeling the behavior of arbitrarily shaped ionic continua under multi-field influence at the macro-length scale. The analytical implementation of this methodology addresses the generation of both the constitutive and the field evolution equations by appropriate use of continuum mechanics, irreversible thermodynamics and electrodynamics. We apply this methodology for the case of electric multicomponent anisotropic hygrothermoelasticity that generates a constitutive model and the associated field equations for a large class of materials capable of electromechanical actuation and sensing. A specialization of this theory for isotropic and bi-component electrohygrothermoelastic materials is provided in terms of the relevant field equations.
Helicopter acoustic alerting system for high-security facilities (2009)

Helicopters present a serious threat to high security facilities such as prisons, nuclear sites, armories, and VIP compounds. They have the ability to instantly bypass conventional security measures focused on ground threats such as fences, check-points, and intrusion sensors. Leveraging the strong acoustic signature inherent in all helicopters, this system would automatically detect, classify, and accurately track helicopters using multi-node acoustic sensor fusion. An alert would be generated once the threat entered a predefined 3-dimension security zone in time for security personnel to repel the assault. In addition the system can precisely identify the landing point on the facility grounds.
Candidate Trees for Terrestrial Carbon Storage in Regions with High Air Pollution and High Water Stress (2017)

Abstract The State of California has now passed a new executive order to reduce, greenhouse gas (GHG), emissions by 40% below 1990 levels by 2030 and 80% below 1900 levels by 2050. A significant portion (37%) of GHG emissions in California comes from non-point sources (i.e. various modes of transportation). Terrestrial carbon storage (i.e. taking the advantage of inherent ability of certain tree species for storing carbon) for reducing the concentration of carbon dioxide (CO2), which is major GHG, from atmosphere is one of many ways to tackle the problem of GHG emissions resulting from non-point sources. In this project, research was focused on finding candidate trees that are drought resistant, native to California, and could continue to sequester atmospheric carbon dioxide in significant quantity over an extended period (&amp;gt;100 years). Several forestry databases were searched for gathering a list of 37 candidate trees. The list was further narrowed downed to 13 which are fast-growing (i.e. reaching reported minimum height for a mature tree in 10 years or less time), emit low to moderate biogenic emissions, can grow in in USDA hardiness zone 8 or above, and have a width less than 20 ft when fully matured. Lastly, 7 candidate trees that are considered big as well as urban trees, are native to Southern California, were identified as the most suitable candidate trees for terrestrial carbon storage in regions with high air pollution and high water stress. Based on simplistic estimates of CO2 absorption per tree per year, it is estimated that a total of 186,000 acres of new forest comprising of top candidate trees identified in the study can help in achieving a 10% reduction in the GHG emissions occurring from transportation sector in the Kern County, California, and a 20% reduction in the Fresno County, California within 10 years of forestation.
Overexpression of Bcl-2 with herpes simplex virus vectors protects CNS neurons against neurological insults in vitro and in vivo (1996)

Previous studies have demonstrated that overexpression of the proto-oncogene bcl-2 can protect neuron and neuron-like cell lines from growth factor deprivation, calcium ionophores, glutamate excitotoxicity, hypoglycemia, free radicals, and lipid peroxidation. To determine whether Bcl-2 exhibits a similar protective effect in CNS neurons, we generated defective herpes simplex virus (HSV) vectors capable of overexpressing Bcl-2 in primary cultures and in the intact brain. Infection of hippocampal cultures with Bcl-2 vectors enhanced neuron survivorship after exposure to adriamycin, a potent oxygen radical generator. Furthermore, dichlorofluorescein measurements indicated that there was a significant reduction in the accumulation of oxygen radicals associated with this insult. Bcl-2 vectors also enhanced survival in cultured neurons after exposure to glutamate and hypoglycemia. Most significantly, the in vivo delivery of the vector protected neurons against adriamycin toxicity in the dorsal horn of the dentate gyrus and focal ischemia in the striatum.
Efficacy of humanized CD19-targeted chimeric antigen receptor (CAR)-modified T cells in children with relapsed ALL. (2016)

3007 Background: Targeted immunotherapy with CTL019, CD19-specific CAR-modified T cells, can produce potent, sustained responses in children with relapsed/refractory acute lymphoblastic leukemia (ALL). However, a subset of patients has limited persistence. We now report on retreatment with murine (CTL019) or humanized (CTL119) CD19-directed CAR T cells. Methods: Patient-derived T cells were transduced ex vivo with a lentiviral vector encoding a CAR with CD3z, 4-1BB, and murine or humanized anti-CD19 scFv domains and activated/expanded with anti-CD3/CD28 beads. Results: Of 55 patients in CR at 1 month after CTL019 infusion (55/59 CR), 3 patients received a repeat infusion of murine CTL019 for CD19+ relapse and 17 for poor persistence at 3 and/or 6 months after initial infusion. Remission was achieved in 1/3 children treated for CD19+ relapse. Of 3 patients reinfused for CD19+ MRD, 1 progressed to CD19+ relapse, 1 became MRD- but had B cell recovery, and 1 had reduced MRD. Reinfusion induced B cell aplasia for a second time in 1/7 children treated for B cell recovery, while 6/7 children reinfused for CD19+ hematogones demonstrated continued B cell aplasia 6-21 months after repeat infusion. Of this group, 6 remained in remission 9-24 months after initial infusion, and 1 experienced a CD19- relapse. Eight children previously treated with CAR T cells (CTL019, n = 5; other, n = 3) were treated on a phase 1 study of humanized CTL119 for B cell recovery (n = 3), CD19+ relapse (n = 4), or no response to prior CAR T cells (n = 1). Cytokine release syndrome (CRS), seen in 4 patients, did not require vasopressor or respiratory support. Responses were seen in 4/8 patients with an ongoing CR of 7 months in 1 patient. 2/4 responding patients were previously resistant to reinfusion of murine CTL019. Conclusions: Reinfusion of murine CTL019 may prolong B cell aplasia in patients with early evidence of poor persistence but is less effective for B cell recovery, suggesting that examination of anti-CAR immune responses will be important to improve durable remission rates. Human CARs may overcome anti-murine immunity, and in the first study of a humanized anti-CD19 CAR, CTL119 induced remission in 50% of patients refractory to murine CAR T cells. Clinical trial information: NCT02374333.
Search for supersymmetry at $$\sqrt{s}=13$$ s = 13 TeV in final states with jets and two same-sign leptons or three leptons with the ATLAS detector (2016)

A search for strongly produced supersymmetric particles is conducted using signatures involving multiple energetic jets and either two isolated leptons (<i>e</i> or [Formula: see text]) with the same electric charge or at least three isolated leptons. The search also utilises <i>b</i>-tagged jets, missing transverse momentum and other observables to extend its sensitivity. The analysis uses a data sample of proton-proton collisions at [Formula: see text] TeV recorded with the ATLAS detector at the Large Hadron Collider in 2015 corresponding to a total integrated luminosity of 3.2 fb[Formula: see text]. No significant excess over the Standard Model expectation is observed. The results are interpreted in several simplified supersymmetric models and extend the exclusion limits from previous searches. In the context of exclusive production and simplified decay modes, gluino masses are excluded at [Formula: see text] confidence level up to 1.1-1.3 TeV for light neutralinos (depending on the decay channel), and bottom squark masses are also excluded up to 540 GeV. In the former scenarios, neutralino masses are also excluded up to 550-850 GeV for gluino masses around 1 TeV.
Substrate Characterization and Outcomes of Catheter Ablation of Ventricular Arrhythmias in Patients With Mitral Annular Disjunction (2022)

Patients with MAD have a complex arrhythmogenic substrate, and catheter ablation is effective in reducing recurrence of ventricular arrhythmias. Substrate mapping and ablation may be considered in these patients.
A Prospective Multicenter Study Evaluating Loading of Osseotite Implants Two Months After Placement: One‐Year Results (1998)

Historically, the recommended time between placement and functional loading of machined-surface dental implants has been 3 months for the mandible and 6 months for the maxilla. However, such recommendations are a result of evaluating randomly chosen healing times during the initial phase of implant development and are based on the subsequent clinical outcome of either implant integration or mobility. In recent years, histologic and experimental studies have shown that specifically designed micro-topographic implant surfaces can result in increased bone-to-implant contact at earlier healing times than obtained with machined-surface implants. Histologic and clinical studies investigating early and immediate implant loading support the premise that implants can be placed into function earlier than previously recommended. With the development of specifically designed implant surfaces and the utilization of time-saving surgical (one-stage surgical protocol) and prosthetic (implant position indexing) techniques, patients are now being restored and returning to function sooner than previously thought possible. The purpose of this multicenter clinical investigation is to evaluate the efficacy of loading Osseotite dental implants (3i-Implant Innovations Inc., Palm Beach Gardens, Florida) at 2 months and to determine the effect of early loading on implant performance and survival. A total of 429 Osseotite implants were placed in 155 patients (87 females and 68 males; mean age 54.0 +/- 13.7 yr), at 10 study centers, and subsequently loaded 2.1 +/- 0.7 months following placement. A single-stage surgical protocol was followed, with implants indexed immediately or impressed 4 to 6 weeks following placement. Patient restorative treatments included placement of 83 single-implant provisional restorations and 129 splinted, two-, three-, and four-implant supported maxillary and mandibular provisional restorations. The mean time from prosthetic loading to the most recent follow-up evaluation was 10 +/- 1.3 months. Seven of the 429 implants did not integrate; of these, six were identified prior to loading and one was identified 1 month after loading. The cumulative implant survival rate was 98.5% at 12.6 months. The cumulative post-loading implant survival rate was 99.8% at 10.5 months. The preliminary results of this clinical investigation suggest that successful functional loading of the Osseotite dental implant is possible at 2 months following noncomplicated implant placement.
LoRa Physical Layer Evaluation for Point-to-Point Links and Coverage Measurements in Diverse Environments (2019)

This paper focuses on Point-to-Point LoRa connections. We report on coverage measurements performed in three distinct environments, i.e., coastal, forest and urban. Our field experiments demonstrate coverage up to 1 km with antennas at only 1.5 m height in an urban scenario. In free Line-of-Sight (LoS) this coverage is extended to 4 km. Based on these results, we are developing a path loss model in future work. The developed hardware and software including measurements are open-source.
A Step Change in Deepwater Test Operations with Downhole Wireless Telemetry (2014)

Abstract Drillstem tests provide crucial information about well deliverability and reservoir characteristics, but gathering such critical data may require many days of rig time, which can be prohibitively expensive in deepwater environments. As the information gathered during the test is generally available only when the string is pulled out of hole, well test engineers are usually conservative when designing the duration of the flow and shut-in periods to ensure sufficient data is acquired to meet test objectives. However, in some cases, the planned test durations were not sufficiently long to capture the necessary reservoir data for interpretation. A relatively common practice of obtaining bottomhole data before the end of the test is running a conventional surface readout (SRO) system on electrical cable to establish communication with the bottomhole gauges, but this technique may pose a major risk to the operations. Recently developed wireless downhole reservoir testing systems can be the solution to this challenge. The system transmits information to and from the bottomhole tools in real time with no risk to the drilling operations. This paper describes a field case where such a system was used on a deepwater well offshore Brazil. The wireless telemetry system took less time to rig up than wireline equipment and allowed the test sequence to be adjusted during the test. The data was available during flow and shut-in periods. It was used to monitor cleanup efficiency in real time as well as to obtain key reservoir information before ending the test. The reservoir engineers were able to ■ observe perforating guns' effect on pressure and confirm dynamic underbalance ■ compute productivity when the well was flowing ■ validate that sufficient data was acquired during the initial and main buildup periods ■ eliminate the need for a wireline run ■ establish reservoir pressure after the initial postperforating flow period. The paper reviews the benefits and limitations of the current technology and makes recommendations on how to use the technology most effectively.
Structure–Activity Relationship Studies of Tetrahydroquinolone Free Fatty Acid Receptor 3 Modulators (2020)

Free fatty acid receptor 3 (FFA3, previously GPR41) is activated by short-chain fatty acids, mediates health effects of the gut microbiota, and is a therapeutic target for metabolic and inflammatory diseases. The shortage of well-characterized tool compounds has however impeded progress. Herein, we report structure-activity relationship of an allosteric modulator series and characterization of physicochemical and pharmacokinetic properties of selected compounds, including previous and new tools. Two representatives, <b>57</b> (TUG-1907) and <b>63</b> (TUG-2015), showed improved solubility and preserved potency. Of these, <b>57</b>, with EC<sub>50</sub> = 145 nM and a solubility of 33 μM, showed high clearance in vivo but is a preferred tool in vitro. In contrast, <b>63</b>, with EC<sub>50</sub> = 162 nM and a solubility of 9 μM, showed lower clearance and seems better suited for in vivo studies. Using <b>57</b>, we demonstrate for the first time that FFA3 activation leads to calcium mobilization in murine dorsal root ganglia.
Multiple transcripts encoded by the ilvGMEDA gene cluster of Escherichia coli K-12 (1992)

We report here that, using Northern (RNA) blots, we identified two relatively stable transcripts of 4.6 and 1.1 kb that correspond to the products of the ilvEDA and ilvE genes and two relatively unstable transcripts of 6.7 and 3.6 kb that correspond to the products of the ilvGMEDA and ilvDA genes. The transcripts were identified by the use of eight probes derived from segments of the ilvGMEDA cluster. In addition, we used two strains with deletions of ilvG or ilvDA and observed the expected decrease in transcript size in Northern blots. Primer extension with reverse transcriptase generated a 169-nucleotide product corresponding to a 5' end within the ilvED intercistronic region, 37 nucleotides from the AUG codon of the ilvD gene. This primer extension product presumably indicates the 5' end of the ilvDA transcript that we detected in Northern blots. The stability of the transcripts was monitored, and RNase E was found to play a major role in ilv transcript degradation. Transcript levels varied in response to growth in the presence of the end product amino acids and in response to the presence of the polar frameshift site in ilvG. Although there have been speculations about the identities and numbers of transcripts derived from the ilvGMEDA cluster on the basis of the identification of some of the sites of transcription initiation and termination, this is the first report of the use of Northern blots to determine the actual sizes and distribution of mRNAs present in vivo.
V2V Path Loss Modeling for Example 5 GHz Overpass Channels (2014)

The overpass is a special over-road structure for vehicle transportation, constituting one type of roadway intersection. Real-time communications between on- and under-overpass vehicles can contribute to optimal route selection and overpass accident warning messaging. In this paper, we provide measurement and analytical results for V2V propagation path loss in the 5 GHz band for two example overpasses. These example overpasses are termed the (i) one-lane metal-bottom overpass, and (ii) two-lane metal-bottom overpass. Due to the unique structure of the overpass, we divide the radio wave propagation spaces around the overpass into four different areas: a two-ray area, a short- term partial shadowing area, a (full) shadowing area, and a long-term partial shadowing area. Analysis and measured results for propagation path loss in these areas are provided. In the two-ray area, a line-of-sight (LoS) path and a ground reflected path are present, whereas in the other areas, the overpass body (floor, walls and columns) block the propagation of energy, increasing path loss. We briefly describe our geometry-based models for the overpass V2V channel, which make use of our analytical models and the measurement data.
State of the art developments in functional hybrid materials (2005)

This issue of Journal of Materials Chemistry highlights recent progress in hybrid materials. Clément Sanchez, Guest Editor, introduces the issue and the academic and industrial importance of the field.
Formation of Polymeric Nanocubes by Self‐Assembly and Crystallization of Dithiolane‐Containing Triblock Copolymers (2017)

Template-free fabrication of non-spherical polymeric nanoparticles is desirable for various applications, but has had limited success owing to thermodynamic favorability of sphere formation. Herein we present a simple way to prepare cubic nanoparticles of block copolymers by self-assembly from aqueous solutions at room temperature. Nanocubes with edges of 40-200 nm are formed spontaneously on different surfaces upon water evaporation from micellar solutions of triblock copolymers containing a central poly(ethylene oxide) block and terminal trimethylene carbonate/dithiolane blocks. These polymers self-assemble into 28±5 nm micelles in water. Upon drying, micelle aggregation and a kinetically controlled crystallization of central blocks evidently induce solid cubic particle formation. An approach for preserving the structures of these cubes in water by thiol- or photo-induced crosslinking was developed. The ability to solubilize a model hydrophobic drug, curcumin, was also explored.
<title>Frequency selective weighted median filters</title> (1999)

In this paper, we propose a frequency selective weighted median (FSWM) filter with arbitrary spectral behavior. The proposed scheme is motivated by the observation on the structure and design procedure of the linear-phase FIR high- pass (HP) filter. An FIR HP filter can be easily obtained by changing the sign of coefficients in odd position. Thus, the output of the HP filter can be represented as the difference between two subfilters which have all positive coefficients. This representation structure of the FIR HP filter is analogous to the difference of estimates (DoE) such as the difference of medians (DoM). The DoM is essentially a robust HP filter which is commonly used in edge detection. Based on this observation, we define a new nonlinear filtering structure consisting of linear combinations of weighted medians. We refer to this new filter class as the FSWM filter. It is shown experimentally that the FSWM filter can offer 'low-pass (LP),' 'HP,' 'band-pass (BP),' and 'band-stop (BS)' frequency characteristics.