gebhart/patrepeval huggingface dataset:
In situ Synthesis of Supramolecular Polymers: Finding the Right Conditions when Combining Covalent and Non‐Covalent Synthesis (2022)

The combination of covalent and non-covalent synthesis is omnipresent in nature and potentially enables access to new materials. Yet, the fundamental principles that govern such a synthesis are barely understood. Here, we demonstrate how even simple reaction mixtures behave surprisingly complex when covalent reactions are coupled to self-assembly processes. Specifically, we study the reaction behavior of a system in which the in situ formation of discotic benzene-1,3,5-tricarboxamide (BTA) monomers is linked to an intertwined non-covalent reaction network including self-assembly into helical BTA polymers. This system shows an unexpected phase-separation behavior in which an interplay of reactant/product concentrations, side-products and solvent purity determines the system composition. We envision that these insights can bring us one step closer to how to design the synthesis of systems in a combined covalent/non-covalent fashion.
A high power density drivetrain-integrated electric vehicle charger (2016)

This paper presents a new architecture for an isolated level 2 on-board electric vehicle (EV) battery charger which is integrated with the EV's drivetrain dc-dc boost converter. The proposed charger leverages many of the existing stages of a highly efficient and power-dense composite-architecture-based drivetrain boost converter. This composite boost converter comprises a buck, a boost and a dc transformer (DCX) stage. In selecting the proposed charging architecture, four alternative approaches to drivetrain integration are identified, explored and compared quantitatively in terms of added weight and charging losses. Out of the considered approaches, the proposed charging architecture provides an effective tradeoff between additional weight and charging losses. This drivetrain-integrated charger adds only a bridgeless-boost-based power factor correction (PFC) ac-dc stage, plus an H-bridge and a single winding to the composite boost converter, to achieve high-power on-board charging functionality without substantial additional weight. A 6.6 kW prototype of the proposed charger has been designed and its PFC stage built and tested. The PFC stage uses a digital implementation of a current sensor-less control strategy and employs effective ways of mitigating zero crossing distortion. The proposed charger architecture reduces the additional weight required for the onboard charging functionality, while achieving greater than 97% peak efficiency for the added charger module PFC stage.
Heat Transfer in Rotating Rectangular Cooling Channels AR=4 With Angled Ribs (2002)

An investigation into determining the effect of rotation on heat transfer in a rib-roughened rectangular channel with aspect ratio of 4:1 is detailed in this paper. A broad range of flow parameters have been selected including Reynolds number (Re=5000–40000), rotation number (Ro=0.04–0.3) and coolant to wall density ratio at the inlet Δρ/ρi=0.122. The rib turbulators, attached to the leading and trailing surface, are oriented at an angle α=45deg to the direction of flow. The effect of channel orientations of β=90 deg and 135 deg with respect to the plane of rotation is also investigated. Results show that the narrow rectangular passage exhibits a much higher heat transfer enhancement for the ribbed surface than the square and 2:1 duct previously investigated. Also, duct orientation significantly affects the leading and side surfaces, yet does not have much affect on the trailing surfaces for both smooth and ribbed surfaces. Furthermore, spanwise heat transfer distributions exist across the leading and trailing surfaces and are accentuated by the use of angled ribs. The smooth and ribbed case trailing surfaces and smooth case side surfaces exhibited a strong dependence on rotation number.
Night vision imaging system lighting evaluation methodology (2005)

In order for night vision goggles (NVGs) to be effective in aircraft operations, it is necessary for the cockpit lighting and displays to be NVG compatible. It has been assumed that the cockpit lighting is compatible with NVGs if the radiance values are compliant with the limits listed in Mil-L-85762A and Mil-Std-3009. However, these documents also describe a NVG-lighting compatibility field test procedure that is based on visual acuity. The objective of the study described in this paper was to determine how reliable and precise the visual acuity-based (VAB) field evaluation method is and compare it to a VAB method that employs less expensive equipment. In addition, an alternative, objective method of evaluating compatibility of the cockpit lighting was investigated. An inexpensive cockpit lighting simulator was devised to investigate two different interference conditions and six different radiance levels per condition. This paper describes the results, which indicate the objective method, based on light output of the NVGs, is more precise and reliable than the visual acuity-based method. Precision and reliability were assessed based on a probability of rejection (of the lighting system) function approach that was developed specifically for this study.
Resolution of DL-Amino Acids by Capillary Zone Electrophoresis Using Chiral Electrolytes (1988)

By combining the separation power of high-voltage capillary zone elctrophoresis with the detection sensitivity of laser-induced fluorescence, subfemtomole amounts of racemic mixtures of labelled amino acids can be completely resolved in short periods of time. The separation is based on the diastereomeric interaction between the amino acids and a chiral Cu(II)-aspartame complex present in the support electrolyte. Effects of electrolyte composition, pH, and temperature are described and discussed as well as linearity and sensitivity of response.
Optimized design and placement of piezoelectric transducers for micromechanical structures subject to membrane stress (2012)

This paper reports on the optimization of the design of piezoelectric transducer elements integrated on doubly-clamped micro-beam resonators. We report and emphasize the often forgotten influence of membrane stresses on defining the dimensions and optimal position of the piezoelectric transducer patches. The study is based on the shift of the inflection line (i.e., points of zero curvature) of the fundamental mode of vibration as a result of (excessive) membrane-stresses. The above is analysed theoretically using numerical models and is confirmed by impedance measurements and optical measurements of fabricated doubly-clamped beam resonators.
Novel SIRT1 Agonists, SRT501 and SRT2183, Induce Expression of DNA Repair Genes and Apoptosis of Ph− Acute Lymphoblastic Leukemia Cells Alone and in Combination with the HDAC Inhibitor LBH589.. (2009)

Abstract Abstract 3083 Poster Board III-20 Histone Deacetylase Inhibitors (HDACi) such as LBH589, which inhibit the zinc containing catalytic domain of HDAC of classes I, II, and IV, demonstrate activity against various malignancies, particularly lymphoid malignancies. SIRT1 is an NAD+ dependent class III histone deacetylase, which deacetylates histones as well as non-histone proteins and is not affected directly by HDACi such as LBH589. It remains controversial whether inhibition of SIRT1 or its activation is more efficacious in anticancer therapy. We have studied the activity of two novel SIRT1 activators, SRT501 and SRT2183, in Philadelphia chromosome negative acute lymphoblastic leukemia (ALL) cell lines. Both pre B (NALM-6, Reh) and T cell (MOLT-4) ALL lines were treated with either SRT501 or SRT2183, as well as in combination with LBH589 and evaluated for biological and gene expression responses. SRT501 induced growth arrest and apoptosis at doses ranging from 10-100 uM, with even the lowest doses inhibiting growth at 72 hours. SRT2183 is much more potent, with growth arrest and apoptosis induced at doses ranging from 1-20 uM. PCR array analysis revealed that SRT2183 treatment leads to increased mRNA levels of pro-apoptosis, growth arrest, and DNA damage response genes. We have previously demonstrated that the activity of LBH589 is mediated in part through upregulation or acetylation of proteins involved in the DNA damage response pathways. Quantitative real-time PCR confirms that the combination of LBH589 with SRT2183 leads to significantly higher expression of GADD45A and GADD45G than either agent alone. The combination of LBH589 plus SRT2183 showed enhanced inhibition of c-Myc protein levels, phosphorylation of H2A.X, and interestingly, increased acetylation of p53 (acetylation of p53 was not seen with SRT2183 alone). In summary, the novel SIRT1 activators SRT501 and SRT2183 show growth inhibitory and pro-apoptotic activity in Ph- ALL alone and enhanced activity in combination with LBH589. Clinical studies of these agents, particularly in combination with HDACi are warranted. Disclosures Kirschbaum: Novartis: Consultancy. Cermak:Sirtris: Employment. Atadja:Novartis: Employment.
HIV Latency (2011)

HIV-1 can establish a state of latent infection at the level of individual T cells. Latently infected cells are rare in vivo and appear to arise when activated CD4(+) T cells, the major targets cells for HIV-1, become infected and survive long enough to revert back to a resting memory state, which is nonpermissive for viral gene expression. Because latent virus resides in memory T cells, it persists indefinitely even in patients on potent antiretroviral therapy. This latent reservoir is recognized as a major barrier to curing HIV-1 infection. The molecular mechanisms of latency are complex and include the absence in resting CD4(+) T cells of nuclear forms of key host transcription factors (e.g., NFκB and NFAT), the absence of Tat and associated host factors that promote efficient transcriptional elongation, epigenetic changes inhibiting HIV-1 gene expression, and transcriptional interference. The presence of a latent reservoir for HIV-1 helps explain the presence of very low levels of viremia in patients on antiretroviral therapy. These viruses are released from latently infected cells that have become activated and perhaps from other stable reservoirs but are blocked from additional rounds of replication by the drugs. Several approaches are under exploration for reactivating latent virus with the hope that this will allow elimination of the latent reservoir.
A novel traction winch for cceanographic moorings (1985)

A new oceanographic mooring winch has been developed at B.I.O. to simplify operations while at the same time reducing the potential for material damage. The winch incorporates a novel arrangement of a grooveless traction roller system to allow mooring line storage at a low tension and provides for automatic separation of successive cable wraps on the rollers to eliminate snagging of terminations. An angled roller mounting arrangement allows a "pack" of cable wraps to glide back and forth across the rollers, following the spooling on the storage reel without the aid of a fairlead system. Storage reels are quickly interchangeable with hydraulic power assist for the separation of different mooring line types or the laying of very long moorings. The device has been employed for the successful deployment and recovery of 5000 m (16,000 ft) long steel/Kevlar moorings and has significantly reduced handling problems.
Presence of Tumor Necrosis is Not a Significant Predictor of Survival in Clear Cell Renal Cell Carcinoma: Higher Prognostic Accuracy of Extent Based Rather Than Presence/Absence Classification (2009)

Tumor necrosis is an adverse prognostic factor in clear cell renal cell carcinoma but prospective evaluation of necrosis on a presence/absence basis shows that it does not provide independent prognostic information. The predictive accuracy of an extent based classification is superior and is retained as an independent prognostic factor. We recommend the scoring of necrosis according to its extent with further subclassification based on a 20% cutoff.
Model of NiV-C interactions with ESCRT. (2016)

&lt;p&gt;Vps28 acts as an adaptor between ESCRT-I and ESCRT-II. The NTD of Vps28 interacts with ESCRT-I via Tsg101-CTD, while the CTD of Vps28 interacts with ESCRT-II possibly via hVps36. The CTD of NiV-C also interacts with Tsg101-CTD, while the potential interaction of NiV-C-MiD with ESCRT-II or other downstream ESCRT factors remains to be defined.&lt;/p&gt;
Morbidity and mortality of the Russian population from acute respiratory viral infections, pneumonia and vaccination. (2018)

In order to assess the impact of influenza vaccination and pneumococcal infection (PI) were studied seasonal morbidity and mortality because of influenza, acute respiratory viral infections (ARVI) and pneumonia among the population of the Russian Federation during 2012-2016 timeframe.The methods. There were analyzed the data of Federal service for surveillance in consumer rights protection and human welfare (Rospotrebnadzor) on influenza vaccination and PI and ARVI morbidity (including influenza), diseases of the respiratory system (DRS). The information on mortality of the population of Russia because of these diseases received from official publications of the Federal State statistics service (Rosstat) and The Ministry of health of the Russian Federation (Ministry of Health of Russia) on the mortality rates of the population of Russia because of these illnesses. Results: the analysis revealed that compared to 2015, in 2016 the incidence rate of ARVI in total Russian population was increased to 5,7%. The incidence rate of influenza in 2016 reached 60,5 cases per 100 thousand of the total population and was higher than the 1,8 times than in 2015 (34,01 on 100 thousand people). The incidence rate of pneumonia in total population was increased by 24,0% in 2016 compared to 2015. According to Rosstat data, the increase of deaths because of influenza and ARVI was mainly in the first semester of 2016, which was associated with influenza epidemic. Mortality because of pneumonia dropped by 10,8% and from other DRS - by 6,9%, which might indicate on the improvement of the quality of medical care and prevention of DRS. Reduction in the mortality rate because of pneumonia also was due to significant influenza vaccination coverage and the increasing number of children and adults vaccinated against PI.
Statistical inference and synthesis in the image domain for mobile robot environment modeling (2005)

We address the problem of computing dense range maps of indoor locations using only intensity images and partial depth. We allow a mobile robot to navigate the environment, take some pictures and few range data. Our method is based on interpolating the existing range data using statistical inferences learned from the available intensity image and from those (sparse) regions where both range and intensity information is present. The spatial relationships between the variations in intensity and range can be efficiently captured by the neighborhood system of a Markov random field (MRF). In contrast to classical approaches to depth recovery (i.e. stereo, shape from shading), we can afford to make only weak assumptions regarding specific surface geometries or surface reflectance functions since we compute the relationship between existing range data and the images we started with. Experimental results show the feasibility of our method.
Electrochemical Template Deposition of Aluminum Nanorods Using Ionic Liquids (2008)

A new method for synthesizing aluminum nanorods has been developed and demonstrated using nonaqueous, ionic liquid electrodeposition in nanoporous, polycarbonate templates. The nanorods, which have diameters of 40 and 60 nm and lengths of 2−4 μm, are characterized by SEM, EDX, UV−visible, and ultrafast spectroscopy.
Complete genome characterization of Rocio virus (Flavivirus: Flaviviridae), a Brazilian flavivirus isolated from a fatal case of encephalitis during an epidemic in São Paulo state (2007)

The flaviviruses of major medical importance in South American countries are yellow fever, dengue, Saint Louis encephalitis, West Nile and Rocio viruses. Rocio virus (ROCV) has been responsible for epidemics of severe encephalitis in Brazil with a case-fatality rate of 10 % and development of sequelae in 20 % of the survivors. We have sequenced and characterized the entire genome of ROCV for the first time, by determining the general traits of the open reading frame and the characteristics of viral genes including the potential cleavage sites, conserved or unique motifs, cysteine residues and potential glycosylation sites. The conserved sequences in the 3'-non-coding region were identified, and the predicted secondary structures during cyclization between 5'- and 3'-non-coding regions were studied. Multiple protein and phylogenetic analyses based on antigenically important and phylogenetically informative genes confirmed a close relationship between ROCV and Ilheus virus (ILHV), together constituting a unique and distinct phylogenetic subgroup as well as the genetic relationship of ROCV with several members of the Japanese encephalitis group. Although ROCV is phylogenetically related to ILHV, our study shows that it is still a virus distinct from the latter virus. This is the first flavivirus uniquely indigenous to Brazil that has been sequenced completely and the genome characterized. The data should be useful for further studies at the molecular level, including construction of infectious clone, identification of gene function, improved disease surveillance based on molecular diagnostic tools and vaccine development.
Creation of interfaces in composite/hybrid nanostructured materials using supercritical fluids (2015)

Abstract By structuring matter at the nano level using highly versatile nanotechnology approaches and apparatus, multifunctionalities with manifestation of enhanced and/or novel useful properties could be attained. The challenges in nanoengineering are the ability to tune the nano-object characteristics (size, distribution, composition, and surface chemistry) and to have a good control on the possible synergy created at the interfaces, especially in the case of complex multifunctional materials. Surface nanoengineering goes hand in hand with the creation of interfaces between nano-objects – either inorganic or hybrid ones – and a closer look in this direction is essential. The present review aims at presenting the possibilities of surface nanoengineering by versatile approaches, namely supercritical fluids processes. Two main routes of nanostructuration, each containing three concepts, will be discussed: supercritical fluid chemical deposition performed in batch mode and continuous supercritical fluid synthesis. Both approaches can be used to access interesting materials with desired properties, with the choice of process depending on what the readers are pursuing.
High ceramide content liposomes with in vivo antitumor activity. (2004)

This work demonstrates proof-of-concept that delivery of exogenous natural ceramide lipid has antitumor activity in vivo, and highlights the potential utility of ceramide-based liposomes as a novel strategy for cancer chemotherapy based on controlled ceramide delivery.
Preface (2014)

Welcome to 2014 IEEE Fifth International Conference on Communications and Electronics (ICCE), socalled IEEE ICCE 2014, which is held at Pullman Danang Beach Resort, Da Nang City, Vietnam from July 30 to August 1, 2014. This biennial event is organized by Hanoi University of Science and Technology (HUST), Danang University of Science and Technology (DUST) and Ho Chi Minh City University of Technology (HCMUT), and co-organized by the School of Electronics and Telecommunications (SET) of HUST. The conference is technically sponsored by the Institute of Electrical and Electronics Engineers (IEEE), the Korean Institute of Communications and Information Sciences - Korean Network Operations and Management (KICS KNOM), the Institute of Electronics, Information and Communication Engineers of Japan (IEICE) - Electronics Society and - Communications Society, also cooperatively sponsored by IEEE Antenna and Propagation Society (APS), IEEE Photonics Society (IPC), as well as IEEE Vietnam Section and IEEE Solid State Circuit Society - Vietnam Chapter.
Return Oriented Programming - Exploit Implementation using functions (2017)

Return Oriented programming was surfaced first a decade ago, and was built to overcome the buffer exploit defense mechanisms like ASLR, DEP (or W^ X) by method of reusing the system code in the form of gadgets which are stitched together to make a Turing complete attack. And to perform Turing complete attack would require greater efforts which are quite complex, and there is very little research available for performing a Turing complete attack. So, in this project, we are systematizing the knowledge of the existing research that can be used to perform a Turing complete ROP attack.
Imaging EQE in CIGS solar cells with high spatial resolution (2015)

We use sub-micron scanning photocurrent microscopy to spatially resolve variations in the collection properties of CIGS thin-film solar cells made from a quaternary target. Spectrally dependent photocurrent measurements show remarkable variations in the current collection properties of the grain boundaries and grain cores. We combine EQE maps with Raman and EBSD scans to infer a direct correlation between the electrical and structural properties of the material comprising these polycrystalline devices.
<title>Indirect networked target-enhanced robust video-interaction telepresence</title> (2002)

Telepresence, especially in the form of interactive video, is becoming critical to modern warfare, delivering intelligence and enhancing situation awareness. This paper describes an interactive video communication system, Indirect Networked Target-Enhanced Robust Video-Interaction Telepresence (INTERVIT), that has been developed at Physical Optics Corporation (POC). The system consists of ground visual sensors, real-time video compression and target assessment and tracking, and secure wireless transmission. The paper describes the design, fabrication and test for an implemented experimental INTERVIT system.
Ethanol Production from Corn Starch in a Fluidized-Bed Bioreactor (1999)

The production of ethanol from industrial dry-milled corn starch was studied in a laboratory-scale fluidized-bed bioreactor using immobilized biocatalysts. Saccharification and fermentation were carried out either simultaneously or separately. Simultaneous saccharification and fermentation (SSF) experiments were performed using small, uniform K-carrageenan beads (1.5-2.5 mm in diameter) of co-immobilized glucoamylase and Zymomonas mobilis. Dextrin feeds obtained by the hydrolysis of 15% dry-milled corn starch were pumped through the bioreactor at residence times of 1.5-4 h. Single-pass conversion of dextrins ranged from 54-89%, and ethanol concentrations of 23-36 g/L were obtained at volumetric productivities of 9-15 g/L-h. Very low levels of glucose were observed in the reactor, indicating that saccharification was the rate-limiting step. In separate hydrolysis and fermentation (SHF) experiments, dextrin feed solutions of 150-160 g/L were first pumped through an immobilized-glucoamylase packed column. At 55 °C and a residence time of 1 h, greater than 95% conversion was obtained, giving product streams of 162-172 g glucose/L. These streams were then pumped through the fluidized-bed bioreactor containing immobilized Z. mobilis. At a residence time of 2 h, 94% conversion and ethanol concentration of 70 g/L were achieved, resulting in an overall process productivity of 23 g/L-h. At residence times of 1.5 and 1 h, conversions of 75 and 76%, ethanol concentrations of 49 and 47 g/L, and overall process productivities of 19 and 25 g/L-h, respectively, were achieved.