gebhart/patrepeval huggingface dataset:
GPU Shape Grammars (2012)

Abstract GPU Shape Grammars provide a solution for interactive procedural generation, tuning and visualization of massive environment elements for both video games and production rendering. Our technique generates detailed models without explicit geometry storage. To this end we reformulate the grammar expansion for generation of detailed models at the tesselation control and geometry shader stages. Using the geometry generation capabilities of modern graphics hardware, our technique generated massive, highly detailed models. GPU Shape Grammars integrate within a scalable framework by introducing automatic generation of levels of detail at reduced cost. We apply our solution for interactive generation and rendering of scenes containing thousands of buildings and trees.
Coarse-grained thread pipelining: a speculative parallel execution model for shared-memory multiprocessors (2001)

This paper presents a new parallelization model, called coarse-grained thread pipelining, for exploiting speculative coarse-grained parallelism from general-purpose application programs in shared-memory multiprocessor systems. This parallelization model, which is based on the fine-grained thread pipelining model proposed for the superthreaded architecture, allows concurrent execution of loop iterations in a pipelined fashion with runtime data-dependence checking and control speculation. The speculative execution combined with the runtime dependence checking allows the parallelization of a variety of program constructs that cannot be parallelized with existing runtime parallelization algorithms. The pipelined execution of loop iterations in this new technique results in lower parallelization overhead than in other existing techniques. We evaluated the performance of this new model using some real applications and a synthetic benchmark. These experiments show that programs with a sufficiently large grain size compared to the parallelization overhead obtain significant speedup using this model. The results from the synthetic benchmark provide a means for estimating the performance that can be obtained from application programs that will be parallelized with this model. The library routines developed for this thread pipelining model are also useful for evaluating the correctness of the codes generated by the superthreaded compiler and in debugging and verifying the simulator for the superthreaded processor.
Non-parametric data predistortion for non-linear channels with memory (2013)

With the growing application of high order modulation techniques, the mitigation of the non-linear distortions introduced by the power amplification, has become a major issue in telecommunication. More sophisticated techniques to counteract the strong generated interferences need to be investigated in order to achieve the desired power and spectral efficiency. This work proposes a novel approach for the definition of a transmitter technique (predistortion) that outperforms the standard methods with respect to both performance and efficiency.
Novel Synthesis of High Surface Area Silicon Carbide by RAPET (Reactions under Autogenic Pressure at Elevated Temperature) of Organosilanes (2005)

We report on a very simple, efficient, and economical synthetic technique that produces SiC of a high surface area, and under different conditions of a silicon carbide−carbon nanocomposite (SCCN) at a relatively low temperature. A high yield of pure products is obtained in a one-stage, single-precursor reaction, without a catalyst. The cracking/dissociation of a triethylsilane precursor is carried out separately in a closed vessel cell (Swagelok) that was heated at 800 °C for 3 h, yielding SCCN, and at 1000 °C for 3 h, yielding SiC. This synthetic process is termed RAPET (Reactions under Autogenic Pressure at Elevated Temperature) process for the synthesis of nanomaterials.
The meniscofemoral ligaments: secondary restraints to the posterior drawer (2003)

We have tested the hypothesis that the meniscofemoral ligaments make a significant contribution to resisting anteroposterior and rotatory laxity of the posterior-cruciate-ligament-deficient knee. Eight cadaver human knees were tested for anteroposterior and rotatory laxity in a materials-testing machine. The posterior cruciate ligament (PCL) was then divided, followed by division of the meniscofemoral ligaments (MFLs). Laxity results were obtained for intact, PCL-deficient, and PCL-MFL-deficient knees. Division of the MFLs in the PCL-deficient knee increased posterior laxity between 15 degrees and 90 degrees of flexion. Force-displacement measurements showed that the MFLs contributed 28% to the total force resisting posterior drawer at 90 degrees of flexion in the intact knee, and 70.1% in the PCL-deficient knee. There was no effect on rotatory laxity. This is the first study which shows a function for the MFLs as secondary restraints to posterior tibial translation. The integrity of these structures should be assessed during both imaging and arthroscopic studies of PCL-injured knees since this may affect the diagnosis and management of such injuries.
The antipsychotic sultopride is overdosed – a PET study of drug-induced receptor occupancy in comparison with sulpiride (2005)

Conventional antipsychotics tend to elicit extrapyramidal symptoms at clinical doses, but dose optimization could reduce the risk of such side-effects. In-vivo receptor-binding studies have suggested that 70-80% of dopamine D2 receptor occupancy provides the desired antipsychotic effects without extrapyramidal symptoms. In terms of dose optimization based on the occupancy, there has not been enough supporting data regarding the clinical doses of the respective antipsychotics. In this study, we measured dopamine D2 receptor occupancy of two conventional benzamide antipsychotics, sulpiride and sultopride, using positron emission tomography, to investigate the rationale of their clinical dose. Although they are prescribed at similar doses (300-1200 mg), the doses required to obtain similar receptor occupancy (70-80%) were quite different: 1010-1730 mg for sulpiride but 20-35 mg for sultopride. In terms of dose, sultopride has about 50 times greater potency than sulpiride based on dopamine D2 receptor occupancy. Evidence for the optimal doses of conventional antipsychotics based on dopamine D2 receptor occupancy would be helpful for rational antipsychotic therapy.
Secretion of Escherichia coli β-lactamase from Bacillus subtilis with the Aid of Usefully Constructed Secretion Vector (1992)

The secretion vector with promoter and signal sequence region of neutral protease gene (npr) from Bacillus amyloliquefaciens was constructed by the technique of polymerase chain reaction (PCR). A unique restriction iste was introduced into the 3' of the signal coding region by the synthesis of PCR primer. To demonstrate the function of cloned promoter and signal sequence, we used the E. coli .betha.-lactamase structural gene as a foreign gene. The signal sequence of .betha.-lactamase gene was deleted by Bal31 exonuclease and only mature region was introduced into the secretion vector. Bacillus subtilis cells transformed by the recombinant vector synthesized the fusion protein and were also capable of removing the signal peptide from the original fusion protein, as judged by the assay of .betha.-lactamase activity and secretion into the growth medium by western blotting.
Stereogenic-at-Metal Zn- and Al-Based N-Heterocyclic Carbene (NHC) Complexes as Bifunctional Catalysts in Cu-Free Enantioselective Allylic Alkylations (2009)

Investigations detailed herein demonstrate the ability of chiral bidentate N-heterocyclic carbenes to promote directly-without the need for a Cu salt-site- and enantioselective C-C bond forming reactions. Within this context, catalytic allylic alkylations of various allylic phosphates with dialkylzinc and trialkylaluminum reagents, performed with chiral bidentate imidazolinium salts and in the absence of a Cu salt, are described. The Cu-free transformations deliver products bearing tertiary or (all-carbon) quaternary stereogenic centers with exceptional site- (>98:<2 S(N)2':S(N)2) and high enantioselectivity [up to 97.5:2.5 enantiomer ratio (er)]. A chiral Zn-based N-heterocyclic carbene (NHC) complex, which serves as the catalyst for the enantioselective allylic alkylation reactions, is isolated and fully characterized. Spectroscopic and X-ray crystallographic studies indicate that the sulfonate group within the stereogenic-at-Zn bidentate complexes coordinates syn to the proximal phenyl substituent of the NHC backbone (vs the initially expected anti). Investigations regarding a related NHC-Al complex reveal similar structural attributes. The studies outlined provide a plausible rationale regarding the mechanism of Cu-free allylic alkylation reactions that involve dialkylzinc or trialkylaluminum reagents as well as the previously reported alkylmagnesium halides. On the basis of the research disclosed, it is proposed that bidentate metal-carbene complexes can serve as effective bifunctional catalysts, a critical attribute that differentiates such NHC-based complexes from the corresponding monodentate variants.
[Regulatory mechanisms of NK cell functions]. (1999)

Natural Killer (NK) cells discriminate self from non-self in a manner distinct from T cells. NK cells exhibit cytotoxicity against "missing-self" by killing any cells in principle except normal self-cells. Cells expressing low levels of self MHC class I molecules such as tumor cells and foreign cells are killed, whereas normal self cells are neglected by NK cells. Although identities of activation receptors triggering NK activity are still unclear, recent studies have revealed molecules inhibiting cytotoxicity against normal self cells. In this review, we summarize current understanding of molecular basis for missing-self hypothesis and control mechanisms of NK cell activation.
Overexpression of membrane glycoprotein PC-1 in MDA-MB231 breast cancer cells is associated with inhibition of insulin receptor tyrosine kinase activity. (1996)

MDA-MB231 human breast cancer cells are unresponsive to insulin and contain a glycoprotein inhibitor of insulin-stimulated insulin receptor (IR) tyrosine kinase activity. Prior studies in both fibroblasts from insulin- resistant non-insulin-dependent diabetes mellitus patients and transfected cells indicate that overexpression of membrane glycoprotein PC-1 reduces IR tyrosine kinase activity. In the present study, we measured PC-1 content and activity in MDA-MB231 and four other human breast cancer cell lines. We observed that PC-1 expression was 3- to 30-fold higher in MDA-MB231 cells when compared with the other breast cell lines. Wheat germ agglutinin extracts of MDA-MB231 cells inhibited IR tyrosine kinase activity. Treatment of these extracts with an antibody to PC-1 significantly reduced their ability to inhibit insulin-stimulated IR tyrosine kinase activity. In addition, when cell clones with different PC-1 activity were selected from MDA-MB231 cells, we found an inverse correlation (r = -0.741, P = 0.006) between the PC-1 activity and the insulin-stimulated IR autophosphorylation. A similar inverse correlation was observed in cell clones derived from the insulin-responsive breast cancer cell line MCF-7. By both immunoprecipitation and cross-linking studies we found PC-1 to be associated with IR. These studies indicate, therefore, that overexpression of PC-1 in MDA-MB231 cells may account, at least in part, for the reduced IR tyrosine kinase activity and suggest that PC-1 is a specific modulator of the IR activity in breast cancer cells.
Galleon: Reshaping the Square Peg of NFV (2021)

Software is often used for Network Functions (NFs) -- such as firewalls, NAT, deep packet inspection, and encryption -- that are applied to traffic in the network. The community has hoped that NFV would enable rapid development of new NFs and leverage commodity computing infrastructure. However, the challenge for researchers and operators has been to align the square peg of high-speed packet processing with the round hole of cloud computing infrastructures and abstractions, all while delivering performance, scalability, and isolation. Past work has led to the belief that NFV is different enough that it requires novel, custom approaches that deviate from today's norms. To the contrary, we show that we can achieve performance, scalability, and isolation in NFV judiciously using mechanisms and abstractions of FaaS, the Linux kernel, NIC hardware, and OpenFlow switches. As such, with our system Galleon, NFV can be practically-deployable today in conventional cloud environments while delivering up to double the performance per core compared to the state of the art.
Dialysis patients and cardiovascular problems: can technology solve the complex equation? (2005)

Patients with end-stage kidney disease undergoing chronic hemodialysis present higher mortality rates compared with the general population. Once patients are on hemodialysis, the risk of cardiovascular death is approximately 30-times higher than the general population, and still remains 10- to 20-times higher after stratification for age, gender and presence of diabetes. Approximately half of patient deaths on dialysis are attributed to cardiovascular causes, including coronary heart disease, cerebrovascular disease, peripheral vascular disease and heart failure. The cardiovascular burden of the hemodialysis patient arises from three different sources: risks inherent to the patient and the uremic syndrome, traditional risk factors and risk factors related to the dialysis therapy. Based on these considerations and the fact that several aspects of the dialysis procedure can cause either a cardiovascular burden or modify the burden already present, new technologies should be directed towards the approach of a possible 'cardioprotective dialysis therapy'. This approach may significantly contribute new techniques and new dialysis machines. Born to make dialysis easy and safe, the new machines feature several options that make monitoring and online hemodiafiltration a simple routine. These and other features could make dialysis better tolerated and more efficient in protecting from fatal cardiovascular events.
Search for long-lived particles decaying to a pair of muons in proton-proton collisions at $$ \sqrt{s} $$ = 13 TeV (2023)

A bstract An inclusive search for long-lived exotic particles decaying to a pair of muons is presented. The search uses data collected by the CMS experiment at the CERN LHC in proton-proton collisions at $$ \sqrt{s} $$ <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"> <mml:msqrt> <mml:mi>s</mml:mi> </mml:msqrt> </mml:math> = 13 TeV in 2016 and 2018 and corresponding to an integrated luminosity of 97.6 fb − 1 . The experimental signature is a pair of oppositely charged muons originating from a common secondary vertex spatially separated from the pp interaction point by distances ranging from several hundred μ m to several meters. The results are interpreted in the frameworks of the hidden Abelian Higgs model, in which the Higgs boson decays to a pair of long-lived dark photons Z D , and of a simplified model, in which long-lived particles are produced in decays of an exotic heavy neutral scalar boson. For the hidden Abelian Higgs model with m (Z D ) greater than 20 GeV and less than half the mass of the Higgs boson, they provide the best limits to date on the branching fraction of the Higgs boson to dark photons for cτ (Z D ) (varying with m (Z D )) between 0.03 and ≈0 . 5 mm, and above ≈0 . 5 m. Our results also yield the best constraints on long-lived particles with masses larger than 10 GeV produced in decays of an exotic scalar boson heavier than the Higgs boson and decaying to a pair of muons.
Outage-Limit-Approaching Channel Coding for Future Wireless Communications: Root-Protograph Low-Density Parity-Check Codes (2019)

A block-fading (BF) channel, also known as a slow-fading channel, is a type of simple and practical channel model that can characterize the primary feature of a number of wireless-communication applications with low to moderate mobility. Although BF channels have received significant research attention in the past 20 years, designing low-complexity, outage-limit-approaching error-correction codes (ECCs) is still a challenging issue. For this reason, a novel family of protograph low-density parity-check (LDPC) codes, called root-protograph (RP) LDPC codes, has been conceived recently. The RP codes not only can realize linear-complexity encoding and highspeed decoding with the help of the quasi-cyclic (QC) structure but can also achieve near-outage-limit performance in different BF scenarios. In this article, we briefly review the design guidelines of such protograph codes with the aim of inspiring further research activities in this area.
Extracellular vesicles from three dimensional culture of human placental mesenchymal stem cells ameliorated renal ischemia/reperfusion injury (2021)

The EVs from 3D culture of hPMSCs have therapeutic potential for I/R-AKI.
Advanced Coastal Ocean Modeling (2018)

The objectives are to develop and evaluate the capabilities of a finite element-based coastal ocean model applied to riverine environments. The high performance computing work undertaken in FYI17 has focused on validation of the Advanced Circulation Model, ADCIRC, in its application as a forecast model for the Lower Pearl River Basin (LPRB), a braided river system.
Characterization of a monolayer graphitic structure (1994)

For small curvatures of a graphitic sheet, carbon atoms can maintain their preferred sp 2 bonding while allowing the sheet to have various three-dimensional geometries, which may have exotic structural and electronic properties. In addition the fivefold rings will lead to a positive Gaussian curvature in the hexagonal network, and the sevenfold rings cause a negative one. By combining these sevenfold and fivefold rings with sixfold rings, it is possible to construct complicated carbon sp 2 networks. Because it is much easier to introduce pentagons and heptagons into the single-layer hexagonal network than into the multilayer network, the complicated morphologies would be more common in the single-layer graphite structures. In this contribution, we report the observation and characterization of a new material of monolayer graphitic structure by electron diffraction, HREM, EELS. The synthesis process used in this study is reported early. We utilized a composite anode of graphite and copper for arc evaporation in helium.
Dandelion (2010)

Dandelion is a tool that extends wikis to support coordinated, collaborative authoring using a tag-based approach. Specifically, users can insert tags in a wiki page to specify various co-authoring tasks. These tags can then be executed to help drive and manage the collaboration workflow, and provide content-centric collaboration awareness for all the co-authors. Four successful pilot deployments and positive user feedback show the practical value of Dandelion, especially its value in supporting a structured, collaborative authoring process often seen in business settings.
Preparation of Perovskite-Type Oxides by the Thermal Decomposition of Heteronuclear Complexes, Ln[Fe<sub><i>x</i></sub>Co<sub>1-<i>x</i></sub>(CN)<sub>6</sub>]⋅4H<sub>2</sub>O (Ln=Pr-Yb) (1997)

Heteronuclear complexes of Ln[FexCo1-x(CN)6]⋅4H2O (Ln=Pr-Yb) were synthesized and their thermal decomposition products were investigated. Thermal decomposition of the complexes results in the formation of perovskite-type oxides for Ln=Pr-Gd even at 800°C. The lattice parameters, a-, b- and c-lattice constants (crystal system: orthorhombic) increase linearly with the ratio of Fe/Co for the perovskite-type oxide. For Ln=Dy through Yb, the Ln2O3 phase is observed as the major product for x=0, but its content decreased with an increase in the Fe content; however, a single phase of the perovskite-type oxide was not formed for x=1. The perovskite-type structure for the Fe systems is easier to form compared with the Co systems. We clarified that the formation of the perovskite-type oxide is mainly affected by the ionic radius of the Ln3+ ion and the T3+ ion (T=Fe or Co).
Subwavelength-grating-induced wavefront aberrations: a case study (2007)

The on-axis wavefront aberrations of a one-dimensional subwavelength-grating antireflection coating on an f/1.7 lens surface are shown to be small with noticeable contributions of defocus, astigmatism, and piston. The astigmatism is 0.02 wave, and the magnitude of the piston approaches one wave peak-to-valley. The difference in aberrations between orthogonally polarized wavefronts, or the retardance aberration, shows 0.01 wave of astigmatismlike variation and more than 0.01 wave of retardance-induced defocuslike variation. A small coupling between polarization states occurs in the form of the familiar Maltese cross, yielding a maximum of 3% coupling in the four diagonal edges of the pupil.
Slow multiphoton excitation as a probe of bimolecular and unimolecular reaction energetics. Multiphoton dissociation of proton-bound alcohol dimers (1981)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSlow multiphoton excitation as a probe of bimolecular and unimolecular reaction energetics. Multiphoton dissociation of proton-bound alcohol dimersD. S. Bomse and J. L. BeauchampCite this: J. Am. Chem. Soc. 1981, 103, 12, 3292–3296Publication Date (Print):June 1, 1981Publication History Published online1 May 2002Published inissue 1 June 1981https://pubs.acs.org/doi/10.1021/ja00402a011https://doi.org/10.1021/ja00402a011research-articleACS PublicationsRequest reuse permissionsArticle Views54Altmetric-Citations42LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Characteristics of the SiN Uniaxial Strained NMOSFET with Channel Fluorine Implantation (2011)

Channel fluorine implantation (CFI) has been successfully integrated with silicon nitride contact etch stop layer (SiN CESL) to further improve the channel hot electron stress (CHES) and constant voltage stress (CVS) reliability of n-channel metal-oxide-semiconductor field-effect-transistor with HfO2/SiON gate stack. Although the improvement of transconductance, drain current and subthreshold swing due to the fluorine passivation is screened out by the effect of uniaxial tensile strain, the result clearly demonstrates that integrating the CFI process in the SiN CESL-strained device can further suppress the CHES- and CVS-induced threshold voltage shift.