gebhart/patrepeval huggingface dataset:
Citywalk: a second generation walkthrough system (2002)

The architectural framework of an advanced virtual walkthrough environment is described and placed in perspective with first generation systems built during the last two decades. This framework integrates support for scalable, distributed, interactive models with plug-in physical simulation to provide a large and rich environment suitable for architectural evaluation and training applications. An outlook is also given to a possible third generation of virtual environment architectures that are capable of integrating different heterogeneous walkthrough models.
Absorption coefficient measurement without interference from the nonlinear index effect (1990)

We present a simple technique to measure the absorption coefficient of molecules which avoids the interference of the distortion of the spatial profile of the laser beam due to self-focusing/self-defocusing.
Development of a High-power Terahertz Free Electron Laser Using a Microtron accelerator and an Electro-magnetic Planar Undulator (2019)

A high-power terahetz FEL is under development at KAERI. We developed a compact microtron to accelerate electrons up to 5 MeV with the energy spread of about 0.4%. An electro-magnetic planar undulator was designed and fabricated to cover the FEL's lasing wavelength range of 350-650μm, The magnetic field strength in the gap of the undulator is changeable from 0.76 to 1.18 T by varying the coil current of the undulator from 1.4 to 2.4 kA. The undulator provides horizontal focusing force to keep the low energy electrons passing a specially-designed narrow waveguide.
Stereochemical investigations of coordinated sulfur stereocenters. X-ray structures of diastereomers of (-)589-[Pd{(R)-CH3CH(1-C10H6)NMe2-C2,N}(R/S)-{Ph2PCH2SMe-P,S}]PF6 (1992)

The reaction between bis(μ-chloro)bis[(R)-1-[(dimethylamino)ethyl]naphthylenyl-C 2,N]dipalladium(II) and 2 mol of the bidentate Ph2PCH2CH2SMe gave a pair of internal diastereomeric complex cations arising from the coordinated sulfur stereocenter. The hexafluorophosphate salt of the diastereomeric mixture crystallizes as a compound with [α]D -35° (CH2Cl2) in the triclinic space group P1 with a = 7.8690 (10) Å, b = 17.837 (2) Å, c = 21.830 (2) Å, α = 82.86 (1)°, β = 87.19 (1)°, γ = 83.39 (1)°, and Z = 4 (R = 0.0412 and Rw = 0.0666). In solution, the complexes exhibit facile intramolecular asymmetric equilibration between diastereomers epimeric at sulfur at room temperature. A coalescence temperature of -90°C was recorded for the interconversion by variable-temperature NMR spectroscopy. Similar behavior was observed for analogous complexes of Ph2AsCH2CH2SMe and Me2AsCH2CH2SMe. © 1992 American Chemical Society.
Heterogeneity in human soluble guanylate cyclase due to alternative splicing (1991)

Two forms of the smaller subunit of the human soluble guanylate cyclase enzyme have been cloned by using PCR. One of the clones (HSGC-1) is identical to bovine and rat lung smaller subunit cyclase. However, the other (HSGC-2) is lacking 33 amino acids. Comparison of its sequence with published partial genomic sequences of bovine guanylate cyclase indicates that HSGC-2 is formed due to alternative splicing.
Milestones and basic principles of grating-based x-ray and neutron phase-contrast imaging (2012)

Views Icon Views Article contents Figures & tables Video Audio Supplementary Data Peer Review Share Icon Share Twitter Facebook Reddit LinkedIn Tools Icon Tools Reprints and Permissions Cite Icon Cite Search Site Citation Franz Pfeiffer; Milestones and basic principles of grating-based x-ray and neutron phase-contrast imaging. AIP Conference Proceedings 31 July 2012; 1466 (1): 2–11. https://doi.org/10.1063/1.4742261 Download citation file: Ris (Zotero) Reference Manager EasyBib Bookends Mendeley Papers EndNote RefWorks BibTex toolbar search Search Dropdown Menu toolbar search search input Search input auto suggest filter your search All ContentAIP Publishing PortfolioAIP Conference Proceedings Search Advanced Search |Citation Search
Structural characterization of an ethylene-tetrafluoroethylene alternating copolymer by polarized Raman scattering (1983)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTStructural characterization of an ethylene-tetrafluoroethylene alternating copolymer by polarized Raman scatteringKaren Zabel, N. E. Schlotter, and John F. RaboltCite this: Macromolecules 1983, 16, 3, 446–452Publication Date (Print):March 1, 1983Publication History Published online1 May 2002Published inissue 1 March 1983https://doi.org/10.1021/ma00237a021RIGHTS & PERMISSIONSArticle Views177Altmetric-Citations10LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (2 MB) Get e-Alerts Get e-Alerts
Experimental demonstration of code position modulation in an O-CDMA system to increase the number of users (2006)

A novel, code-position modulation(CPM) that permits increase in the number of active users proposed and experimentally demonstrated. CPM-O-CDMA system with 6-asynchronous users at bit-rate 2.5 Gb/s and BER<1E-9 demonstrated to increase the bit-rate by 4X.
Token-Based Adaptive Time-Series Prediction by Ensembling Linear and Non-linear Estimators: A Machine Learning Approach for Predictive Analytics on big Stock Data (2018)

With technological advancements, big data can be easily generated and collected in many applications. Embedded in these big data are useful information and knowledge that can be discovered by machine learning and data mining models, techniques or algorithms. A rich source of big data is stock exchange. The ability to effectively predict future stock prices improves the economic growth and development of a country. Traditional linear approaches for prediction (e.g., Kalman filters) may not be practical in handling big data like stock prices due to highly nonlinear and chaotic nature. This lead to the exploitation of various nonlinear estimators such as the extended Kalman filters, expert systems, and various neural network architectures. Moreover, to lessen the potential shortcomings of individual algorithms, ensemble approaches have been created by averaging values across different algorithms. Existing ensemble techniques mostly basket-together a collection of sample-based algorithms that are catered to nonlinear functions. To the best of our knowledge, traditional linear estimators have not yet been incorporated into such an ensemble. Hence, in this paper, we propose a machine learning (specifically, token-based ensemble) algorithm that utilizes both linear and nonlinear estimators to predict big financial time-series data. Our ensemble consists of a traditional Kalman filter, long short-term memory (LSTM) network, and the traditional linear regression model. We also explore the adaptive properties in short-term high-risk trading in the presence of noisy data like stock prices and demonstrate the performance of our ensemble.
Central venous catheter related thrombosis in haematology patients and prediction of risk by screening with Doppler‐ultrasound (2003)

Patients with a central venous catheter (CVC) who receive intensive chemotherapy or a stem cell transplantation for haematological disease are at risk for developing CVC-related thrombosis. To study the incidence of thrombosis, 105 consecutive patients underwent serial Doppler-ultrasound and we evaluated whether clinically manifest thrombosis could be predicted by screening with Doppler-ultrasound. Patients with subclavian or jugular inserted CVCs were clinically assessed each day for signs and symptoms of thrombosis. Additional Doppler-ultrasound screens were performed weekly by an independent physician in all patients until CVC removal. Doppler-ultrasound recordings were assessed by two blinded observers. In cases of clinically suspected thrombosis, the attending physicians followed routine diagnostic and therapeutic procedures. The overall cumulative incidence of CVC-related thrombosis was 28.6% (30 of 105 patients). Of the 30 patients with thrombosis, 26 had subclinical thrombosis by Doppler-ultrasound, nine of whom developed clinically manifest thrombosis later. Four patients had clinically manifest thrombosis without prior abnormal Doppler-ultrasound. In cases of subclinical thrombosis the risk of developing symptomatic disease increased sevenfold (34.6% vs. 5.1%). Doppler-ultrasound screening may be useful to identify those patients that are at high and low risk for clinically manifest CVC-related thrombosis.
P4‐254: A novel medical food Souvenaid® for AD patients can be used safely in combination with an acetylcholinesterase inhibitor in an aged rat model (2011)

Preclinical studies have demonstrated synergistic actions of specific nutrients, leading to increased formation of synaptic membrane, reduced Abeta production, and improved memory. Based on these findings, a multi-nutrient concept known as Fortasyn™ Connect (FC) was designed for AD patients. The medical food Souvenaid® containing FC was tested in a randomized controlled trial and showed improvement in memory in drug-naive mild AD patients. Results of this trial suggest a potential role for Souvenaid® in the overall management of AD. Current standard practice for treatment of AD, acetylcholinesterase inhibitors (AChEI) have been reported to induce common adverse events including digestive, cardiovascular, and urogenital effects. The present study in aged rats was designed to see whether Souvenaid may be used safely in concordance with AChEI, i.e. without increasing possible side effects. 24-months-old rats were fed either a diet containing FC or a Control diet and were administered increasing doses of an AChEI. Brain AChE activity was measured in addition to physiological parameters reported to be influenced by AChEI, such as body temperature (BT), heart rate, micturition and locomotor activity (LA). Administration of AChEI confirmed earlier reported reductions of brain AChE-activity. In addition, the AChEI dose-dependently reduced BT and LA, while it increased micturition. The FC diet did not have a negative effect on brain AChE activity or on any of the other physiological parameters studied. This study showing the absence of interaction between the FC diet and an AChEI on an extensive set of cholinergic parameters, provides a good starting point to evaluate the potential benefits of Souvenaid® in AD patients that receive standard pharmacological treatment in a clinical setting. Currently, Souvenaid® is being tested in such an add-on setting, the S-Connect study (NTR1683).
Moving activity of pregnant tethered sows : determination of some factors of variations (1985)

mococcus and its pathogenicity is very similar in man and animals. At present, the strepto- coccal disease, Streptococcus suis (group R) is considered to be related to management conditions, herd selection and stimulated by stress situations such as vaccinations, trans- ports, etc.
Experimental Validation of Nonlinear Predictive Algorithms for Steering and Braking Coordination in Limit Handling Maneuvers (2010)

Experimental results are presented for two low complexity Model Predictive Control (MPC) approaches to autonomous path following via coordination of steering and braking in passenger vehicles. The two approaches, presented in [1–3], are validated in high speed double lane changes on snow. The results show that the proposed approaches are able to stabilize the vehicle up to 60 Kph and operate in wide regions of the tire characteristics.
Metabolic Labeling of Sialic Acids in Living Animals with Alkynyl Sugars (2009)

Sialome sweet sialome: As sialic acids are involved in many host-pathogen recognition events and are markers of embryonic and malignant tissues, there is great interest in methods for the enrichment and identification of sialylated glycoproteins from complex tissues. Now N-(4-pentynoyl)mannosamine can be used to metabolically label sialylated glycoproteins in living animals, enabling future identification of new biomarkers.
Harmonically Related Concurrent Tri-Band Behavioral Modeling and Digital Predistortion (2019)

With the increase in demands of the multi-band and ultra-wideband-based transmitters, the research interest in power amplifiers (PAs) is moving toward the designing of multi-band and ultra-wideband PAs. This leads to unprecedented challenges, such as the possibility of multiband transmission at harmonic frequencies. This brief investigates and presents the novel digital predistortion (DPD) models for linearization of a previously uninvestigated case of concurrent tri-band PA at harmonic frequencies. This brief analyzes the intermodulation terms which are producing harmonic distortions and proposes 3-D harmonic memory polynomial (3D-HMP) and harmonic volterra spline (3D-HVS) models for mitigation of in-band harmonic, cross-modulation, and intermodulation distortions. The results show that the proposed 3D-HMP and 3D-HVS DPD models have linearization performance in terms of adjacent channel power ratio below -50 dBc.
Dynamics of low capillary number interfaces moving through sharp features (2005)

The success of any nanoimprint process depends upon its ability to exactly reproduce the template pattern. Thus, complete filling of recessed features in the template is an important issue that is controlled by the dynamics of the flow through these sharp structures. At these small scales, capillary forces are large and must be included in the fluid flow model. The mechanism of interface advancement at low capillary number through sharp rectangular features is useful for understanding how and why features fill or trap air. In this study we present a two-dimensional simulation of this feature filling to capture the details of the process, including the viscous and capillary effects. Fluid is injected into the channel between the template and substrate, where the fluid–air interface soon encounters a rectangular feature with some height greater than the channel gap. As the fluid advances through the channel, the shape of the interface is a circular arc due to the strong capillary forces. The interface maintains this circular arc as it negotiates the first sharp corner of the feature; the upper contact line effectively pins to the initial corner of the feature as it moves around this corner, during which time the lower contact line continues to advance forward along the substrate surface, causing the interface to stretch. For sufficiently wide or shallow features, once the upper contact line has negotiated the first corner and has moved vertically up the inner wall of the feature, it must move through the top corner of the feature. At this point the interface undergoes a rapid reconfiguration from a high surface area circular arc to a lower surface area circular arc inside the feature. Alternatively, for narrow or high features, the stretched interface can catch on the far, final corner of the feature, trapping air inside the feature and preventing filling. The conditions for filling are studied parametrically for a variety of wetting contact angles and feature dimensions with both the simulation and a simpler, successful geometric model. The dynamics of the feature filling suggest an effective boundary condition for a macroscopic lubrication model of the imprint lithography process in which a critical pressure is required to move fluid through a feature.
Recombinant single‐chain and disulfide‐stabilized Fv‐immunotoxins that cause complete regression of a human colon cancer xenograft in nude mice (1996)

Monoclonal antibody (MAb) 55.1 specifically recognizes an antigen on the surface of human colon adenocarcinoma cells. We constructed recombinant immunotoxins composed of the heavy- and light-chain variable regions of MAb 55.1 fused to a recombinant form of Pseudomonas exotoxin (PE). The heavy- and light-chain variable regions are stabilized by 2 means. One is by a flexible peptide linker to form a single-chain antigen binding protein (scFv) and the second by an interchain disulfide bond engineered between structurally conserved framework regions. These are termed disulfide stabilized Fvs (dsFv). The 2 Fv forms are fused to truncated forms of PE lacking the cell binding domain. The recombinant scFv- and dsFv-immunotoxins were expressed in E. coli and purified to near homogeneity. The scFv- and dsFv-immunotoxins were shown to be specifically cytotoxic to human colon adenocarcinoma cell lines. The scFv-immunotoxin containing PE38KDEL was more active than the immunotoxin containing PE38 with the native carboxyl terminus (REDLK). However, the PE38KDEL immunotoxin is about 2-fold more toxic in mice, and therefore it does not appreciably increase the therapeutic window in mice. Intravenous administration of the scFv- and dsFv- recombinant immunotoxins caused complete regression of a human colon carcinoma (Colo205) growing subcutaneously in immunodeficient mice. The dsFv-immunotoxin has better antitumor activity compared with its scFv-immunotoxin counterpart. © 1996 Wiley-Liss, Inc.
Mis‐annotations of a promising antibiotic target in high‐priority gram‐negative pathogens (2020)

The rise of antibiotic resistance combined with the lack of new products entering the market has led to bacterial infections becoming one of the biggest threats to global health. Therefore, there is an urgent need to identify novel antibiotic targets, such as dihydrodipicolinate synthase (DHDPS), an enzyme involved in the production of essential metabolites in cell wall and protein synthesis. Here, we utilised a 7-residue sequence motif to identify mis-annotation of multiple DHDPS genes in the high-priority Gram-negative bacteria Acinetobacter baumannii and Klebsiella pneumoniae. We subsequently confirmed these mis-annotations using a combination of enzyme kinetics and X-ray crystallography. Thus, this study highlights the need to ensure genes encoding promising drug targets, like DHDPS, are annotated correctly, especially for clinically important pathogens. PDB ID: 6UE0.
Effects of hypothermia on evoked potentials, magnetic resonance imaging, and blood flow in focal ischemia in rabbits. (1992)

These results demonstrate that hypothermia can improve evoked potentials and magnetic resonance parameters in permanent focal ischemia. However, moderate hypothermia (30 degrees C) appears to also significantly decrease blood flow in the ischemic brain.
Molecular cloning of telomere-binding protein gens fromStylonchia mytilis (1991)

A telomere-binding protein heterodimer of 56 kDa (alpha) and 41 kDa (beta) subunits binds specifically to Oxytricha nova telomeres. Genes encoding both subunits have been cloned previously. Here we report molecular cloning and sequence analysis of the homologous genes in Stylonychia mytilis. The derived amino acid sequences were 79% identical for the alpha subunits and 77% identical for the beta subunits. Three repeats of a Leu/Ile heptad were found in each subunit, which might be involved in heterodimer formation. A 360 amino acid region of the Stylonychia mytilis alpha subunit was found to share weak sequence similarity with human vimentin, suggesting the possibility of a relationship between telomeres and intermediate filaments.
Ultra-Lightweight 548–1080 Gate 166Gbps/W–12.6Tbps/W SIMON 32/64 Cipher Accelerators for IoT in 14nm Tri-gate CMOS (2018)

A family of 32b data/64b key SIMON cipher accelerators, each reconfigurable for encrypt/decrypt modes and fabricated in 14nm tri-gate CMOS, is optimized for a range of area and performance targets: (i) a 1080-gate one round/cycle design occupying 136μm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> die area uses reconfigurable circuits for forward/reverse key generation, (ii) a 752-gate 16 cycles/round bit-serial design with a single round/key logic bit-slice lowers layout area by 38% to 85μm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> , and (iii) latch-based key/text storage for the bit-serial circuit reduces area further by 22% to 66μm <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</sup> at 272 cycles/round for a 548-gate design with measured 11.4Mbps, 209μW, 750mV operation. Ultra-low voltage circuit optimizations enable peak energy efficiency from 166Gbps/W at 380mV for the bit-serial latch-based design to 12.6Tbps/W at 260mV for the parallel, one round/cycle design.
Experimental Studies to Define the Geometry of the Flow Convergence Region: Laser Doppler Particle Tracking and Color Doppler Imaging (1992)

The color flow convergence method for calculating volume flow through regurgitant or forward flow restrictive orifices has gained significant interest and a number of in vitro studies have suggested that this method is accurate, even in pulsatile models. Clinical application of the method over a wide range of conditions will require improved understanding of the effect of orifice size, flow geometry, and flow rate on the flow convergence geometry. In this study, we performed laser particle tracking investigations to allow visualization of streamlines into stenotic orifices. These streamlines are theoretically perpendicular to the isovelocity surfaces used for flow convergence calculations. We compared those observations to color flow map, flow convergence images obtained with a Toshiba 160A for orifices 5 to 15 mm 2 with flow rates of 1.5 to 9.7 L/min. Our results show that for large orifices, low flow rates, and/or low pressure gradients, more oblique streamlines in the velocity of the orifice correspond to nonhemispherical, but more elliptical, flow convergence geometries. This can be corrected for by using lower Nyquist limits and calculating flow convergence at greater distances from the orifice. Under high flow and high gradient conditions, increased Nyquist limits and shorter aliasing radii are more suitable. Our studies yield insights into flow convergence geometry and yield corrective procedures to improve volume flow calculation.