gebhart/patrepeval huggingface dataset:
Role of intracellular energy in insulin's ability to activate 3-O-methylglucose transport by rat adipocytes (1980)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRole of intracellular energy in insulin's ability to activate 3-O-methylglucose transport by rat adipocytesJason Siegel and Jerrold M. OlefskyCite this: Biochemistry 1980, 19, 10, 2183–2190Publication Date (Print):May 13, 1980Publication History Published online1 May 2002Published inissue 13 May 1980https://pubs.acs.org/doi/10.1021/bi00551a029https://doi.org/10.1021/bi00551a029research-articleACS PublicationsRequest reuse permissionsArticle Views22Altmetric-Citations40LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Laparoscopic Nephrectomy: Initial Case Report (1991)

A tumor-bearing right kidney was completely excised from an 85-year-old woman using a laparoscopic approach. A newly devised method for intra-abdominal organ entrapment and a recently developed laparoscopic tissue morcellator made it possible to deliver the 190 gm. kidney through an 11 mm. incision.
Combining Personality Traits with Traditional Risk Factors for Coronary Stenosis: An Artificial Neural Networks Solution in Patients with Computed Tomography Detected Coronary Artery Disease (2013)

Background. Coronary artery disease (CAD) is a complex, multifactorial disease in which personality seems to play a role but with no definition in combination with other risk factors. Objective. To explore the nonlinear and simultaneous pathways between traditional and personality traits risk factors and coronary stenosis by Artificial Neural Networks (ANN) data mining analysis. Method. Seventy-five subjects were examined for traditional cardiac risk factors and personality traits. Analyses were based on a new data mining method using a particular artificial adaptive system, the autocontractive map (AutoCM). Results. Several traditional Cardiovascular Risk Factors (CRF) present significant relations with coronary artery plaque (CAP) presence or severity. Moreover, anger turns out to be the main factor of personality for CAP in connection with numbers of traditional risk factors. Hidden connection map showed that anger, hostility, and the Type D personality subscale social inhibition are the core factors related to the traditional cardiovascular risk factors (CRF) specifically by hypertension. Discussion. This study shows a nonlinear and simultaneous pathway between traditional risk factors and personality traits associated with coronary stenosis in CAD patients without history of cardiovascular disease. In particular, anger seems to be the main personality factor for CAP in addition to traditional risk factors.
Artificial Wideband Multi User Channels for Rural High Speed Vehicle to Vehicle Links (2011)

Long haul transport can be considered an obvious deployment scenario for communication between vehicles travelling in convoy, where environments will be comparable to that of a rural highway. Therefore this paper addresses antenna array techniques applicable to such circumstances, which provide little scattering to the propagation channel and little support for diversity. Only beamforming is realistically suited to increase the capacity in the vehicle to vehicle link. However, the possibility to enable multi user channels is limited in such environments since the propagation channels are highly correlated when more than two vehicle to vehicle links are in close proximity. The deliberate introduction of delay spread through wide spaced and combined multiple antenna topology thus creating an artificial wideband fading channel is proposed in this paper, which results in de-correlated vehicle to vehicle links. Measurements and experimental results are presented that demonstrate the means by which uncorrelated wideband channels between separate vehicle to vehicle links can be formed to enable multi user capabilities specific to vehicles on a rural highway.
Designing Oxidation Catalysts: Are We Getting Better? (2003)

Abstract For Abstract see ChemInform Abstract in Full Text.
ChemInform Abstract: Amine‐Induced Rearrangements of 2‐Bromo‐1‐(1H‐indol‐3‐yl)‐2‐methyl‐1‐ propanones: A New Route to α‐Substituted Indole‐3‐acetamides, . beta.‐Substituted Tryptamines, α‐Substituted Indole‐3‐acetic Acids and Indole β‐Aminoketones. (1991)

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Managing a camera system to serve different video requests (2003)

This paper presents a camera system called FlySPEC. In contrast to a traditional camera system that provides the same video stream to every user, FlySPEC can simultaneously serve different video-viewing requests. This flexibility allows users to conveniently participate in a seminar or meeting at their own pace. Meanwhile, the FlySPEC system provides a seamless blend of manual control and automation. With this control mix, users can easily make tradeoffs between video capture effort and video quality. The FlySPEC camera is constructed by installing a set of pan/tilt/zoom (PTZ) cameras near a high-resolution panoramic camera. While the panoramic camera provides the basic functionality of serving different viewing requests, the PTZ camera is managed by our algorithm to improve the overall video quality that may affect users watching details. The video resolution improvements from using different camera management strategies are compared in the experimental section.
Markov Paging (2000)

This paper considers the problem of paging under the assumption that the sequence of pages accessed is generated by a Markov chain. We use this model to study the fault-rate of paging algorithms. We first draw on the theory of Markov decision processes to characterize the paging algorithm that achieves optimal fault-rate on any Markov chain. Next, we address the problem of devising a paging strategy with low fault-rate for a given Markov chain. We show that a number of intuitive approaches fail. Our main result is a polynomial-time procedure that, on any Markov chain, will give a paging algorithm with fault-rate at most a constant times optimal. Our techniques show also that some algorithms that do poorly in practice fail in the Markov setting, despite known (good) performance guarantees when the requests are generated independently from a probability distribution.
Technology Requirements for an Alamouti-Coded 100 Gb/s Digital Coherent Receiver Using 3 × 3 Couplers for Passive Optical Networks (2018)

Digital coherent receivers employing Alamouti-coding are a promising solution for passive optical networks (PON) with downstream rates of 100 Gb/s/λ. To reduce the cost by utilizing high-volume photodiodes designed for 25 Gb/s data-center applications, we consider 28-Gbaud 16-QAM modulation format detected with a single-polarization coherent receiver based on a 3 × 3 coupler with single-ended detection. We investigate two alternative configurations: first, a receiver with a symmetric 3 × 3 coupler and second, an IQ coupler (asymmetric 3 × 3 coupler) with Alamouti-coding based polarization diversity. In this paper, we present a detailed investigation as to the feasibility of both the receivers for a wide range of parameters including quantization noise, relative intensity noise, I/Q mismatch, etc. It is found that such receivers can be realized with commercially available components. We also quantify the penalty associated with nonideal components to allow for lower cost designs with reduced specifications suitable for access applications. In addition, we present the adaptive DSP algorithms required to recover data for a single-carrier Alamouti-coded signal. Considering both linear and nonlinear impairments, a power budget of 36.4 dB and 33.1 dB is found at BER of 3.8 × 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-3</sup> for a receiver with symmetric 3 × 3 coupler and IQ coupler, respectively, and thereby proving their applicability as receivers for 100 Gb/s/λ PON.
Add-on benzodiazepines for psychosis-induced aggression (2019)

In severely psychotic, violent patients, add-on benzodiazepines are often prescribed with antipsychotic agents. We examined aggression, suicidality, and self-harm among psychotic patients treated with antipsychotic monotherapy, compared with those treated with add-on benzodiazepines, during the first 2 weeks of psychiatric hospitalization to clarify the association of add-on benzodiazepines and aggression. Electronic medical records of 400 patients consecutively admitted to Abarbanel Mental Health Center from 2012 to 2014 for psychosis, and remained hospitalized for at least 2 weeks were evaluated. Violence toward staff, patients, and property, physical restraints, seclusion, self-harm, and suicidal thoughts, were examined. Falls and referrals to general hospital indicated adverse medication effects, and were recorded. No significant between-group differences were found for sex, age, psychiatric diagnosis, compulsory admissions, antipsychotic dosages, number of previous hospitalizations, or hospitalization days were detected. Maximum dosage for antipsychotics in the monotherapy group did not reveal a statistically significant difference from the add-on benzodiazepine group (2.2 ± 1.4 vs. 2.2 ± 1.3, respectively), expressed in defined daily dose. There were no between-group differences in frequency of any violent event, incidence of self-harm, suicidal thoughts, frequency of falls, and/or referrals to a general hospital. Addition of benzodiazepines might be unnecessary. Benzodiazepine addition to antipsychotic drugs for patients with severe psychosis should be with caution.
819 DEVELOPMENT OF ANGIOTENSIN II DNA VACCINE FOR HYPERTENSION (2012)

Objectives: The aim of this study is to design DNA vaccines for high blood pressure (BP) toward to human vaccine therapy to treat hypertension. Design and methods: We selected angiotensin II (Ang II) as a target antigen. Plasmid vector encoding Hepatitis B core (HBc)-Ang II fusion protein was constructed, as HBc forms sphere-like structure by self-aggregation and the presented fusion peptide in the position of B cell epitope of HBc protein could induce high titer antibody to the target peptide. Plasmid DNA (HBc-Ang II or HBc) or saline were injected to the back skin of spontaneously hypertensive rats (SHR) three times (at 0, 2, 4 weeks) by needle less injection system. Results: Anti-Ang II antibody was successfully produced, and sustained at least up to 6 months. Consistently, systolic BP was lower in HBc-Ang II group after the immunization (at 12 weeks: 188.1 ± 15.8 mmHg in HBc-Ang II group vs. 221.5 ± 14.6 mmHg in HBc group, P < 0.01), and BP reduction was continued at least up to 6 months. Of importance, perivascular fibrosis in heart tissue was significantly reduced in HBc-Ang II group. T cell activity of cytokine production responded to Ang II or angiotensinogen was not detected without any apparent pathologically toxic observation. Conclusions: The present study demonstrated that Ang II DNA vaccine to SHR significantly lowered high BP at least up to 6 months. Future development of DNA vaccine to hypertension might provide new therapeutic option to treat hypertensive population.
Effective UV Exposure Technique by Holographic Optical Element for the Fabrication of Long Period Fiber Grating (2003)

We developed a new and effective technique for the fabrication of long period fiber gratings (LPFGs) with UV exposure energy by using a holographic optical element (HOE). Our HOE exposure technique produces a stripe line beam whose period and contrast are variable through a computer generated HOE. The HOE exposure technique is twice as efficient in terms of energy as the conventional contact mask method, because the HOE converts a nonuniform input beam into a stripe line beam, while in the conventional contact mask method, the beam loses energy at two steps: the beam homongenizer and the amplitude mask. In order to clarify which beam intensity profile is efficient for LPFG fabrication, the contrast of the stripe line beam profile was varied from 0.12 to 1.33, which is defined as the ratio of the first harmonics to the DC component of the stripe line beam. The result shows that the increase of the peak loss during the LPFG writing process is strongly dependent on the first harmonics amplitude of the stripe line beam profile, not simply on the total exposure energy, though the peak wavelength shift is linear to the total exposure energy. That is to say, the higher contrast beam effectively reduces the exposure energy to achieve the requisite peak loss.
Real-time quality evaluation of adaptation strategies in VoD streaming (2016)

HTTP Adaptive Streaming (HAS) has become a popular trend for multimedia delivery nowadays. Because of throughput variations, video adaptation methods are needed to avoid buffer underflows. In this context, it is also important to evaluate the overall video quality of a session. In this paper, we investigate a quality model that can evaluate a session quality as well as different adaptation strategies in real time. We use the histogram of segment quality values and the histogram of quality gradients in a session to model the overall video quality. Then, our quality model is employed to evaluate, for the first time, the cumulative quality of typical adaptation methods in real time. It is found that, to provide a high quality level, the client should avoid changing versions frequently and drastically.
Additive Pulse Compression Modelocking Using Nonlinear Polarization Evolution (1991)

Single-mode rare-earth-doped fibers[1] are an ideal medium for the generation of ultra-short pulses. Long interaction lengths for nonlinear processes d o w a very effective exploitation of nonlinear intra-cavity pulse-shaping mechanisms and d o w to mode-lock the f d glass laser bandwidth even in the presence of dominant inhomogeneous broadening. Stable femto-second pulse generation in fiber lasers generally requires the presence of both passive frequency- and amplitude modulation to be present in the cavity[2]. Passive frequency modulation is obtained by self-phase .modulation in the presence of overall negative group velocity dispersion (-GVD) and amplitude modulation is induced by an intra-cavity nonlinear pulse- shaping mechanism[3].
High spatial frequency structured light imaging texture analysis using Gabor filtering differentiates tumor from normal tissue subtypes (2019)

A recent clinical study involved multi-spatial frequency (0.00, 0.15, 0.61, 1.37 mm<sup>-1</sup> ), multi-spectral (490, 550, 600, 700 nm) structured light imaging (SLI) of freshly excised, bread-loafed breast conserving surgery tumor specimens. The specimens contained regions of interest (ROIs) of confirmed and homogeneous histological categories of breast tumor tissue determined by expert histopathological analysis. ROIs were sampled into ~4x4mm sub-images before conversion into Gabor filter bank feature vectors. Feature vectors were used in binary, benign-malignant classification scenarios using a support vector machine classifier and 8-fold cross validation. Classification was performed first on feature vectors containing only planar (0.00 mm<sup>-1</sup> ) 490 nm monochromatic SLI data. For comparison, a second set of feature vectors from the same sub-images contained the same planar 490 nm illumination data concatenated with high spatial frequency (1.37 mm<sup>-1</sup> ) 490 nm monochromatic SLI data. The classification performance of each filter bank was determined for both sets of feature vectors based on receiver operating characteristic (ROC) area under the curve (AUC) values. Gabor filtering and subsequent classification revealed that surface tissue textures exhibited strong rotational dependence and that high spatial frequency surface tissue features were more diagnostic than low spatial frequency surface tissue features. A Gabor filter bank that included 4 relatively high spatial frequencies (0.70-1.98 mm<sup>-1</sup> ) and 8 rotation angles (0-157.5&deg;, equally spaced) achieved ROC AUC values &lt;0.9 for 9 of 12 binary tissue subtype classifications.
Effective Thermodynamics of Artificial Spin Ice (2007)

We analyze the rotational demagnetization of artificial spin ice, a recently realized array of nanoscale single-domain ferromagnetic islands. Demagnetization does not anneal this model system into its anti-ferromagnetic ground state: the moments have a static disordered configuration similar to the frozen state of the spin ice materials. We demonstrate that this athermal system has an effective extensive degeneracy and we introduce a formalism that can predict the populations of local states in this ice-like system with no adjustable parameters.
Supplementary Figure 2 from Dual mTORC1/2 and HER2 Blockade Results in Antitumor Activity in Preclinical Models of Breast Cancer Resistant to Anti-HER2 Therapy (2023)

&lt;p&gt;PDF file, 792KB, Biochemical analyses of trastuzumab/lapatinib resistant cells treated with lapatinib.&lt;/p&gt;
Klir and Yuan's Fuzzy Sets and Fuzzy Logic (1996)

During the past thirty years we have been witnessing the process of emerging and extensive maturing of fuzzy set theory as a paradigm shift in managing complexity, uncertainty, and subjectivity. This process has been accompanied by a growing number of books focusing on the theoretical and practical aspects of fuzzy sets-a clear indication that the fundamentals of a new scientific discipline were being built. Among the recently published monographic texts, the new book by George J. Klir and Bo Yuan, Fuzzy Sets and Fuzzy Logic, is an exceptional achievement. The major focus of this book is on the fundamental issues of fuzzy set theory (part 1, chapters 1-9). These issues are introduced in the environment of some well-established disciplines, e.g. classical set theory, probability theory, Dempster-Shafer theory, information theory, etc. Such an approach provides the reader with an efficient methodology for catching the essence of the subject by making association and comparisons with classical concepts, definitions, and terms. The comprehensive coverage of the overall fuzzy machinery is further supported by a nice set of examples and work problems, and by an overview of the major practical areas of application of fuzzy sets. The problem of managing uncertainty is used as a major vehicle for representing the power and the applicability of fuzzy set theory. Since this issue has an influence on a wide variety of engineering problems, the book presents a natural bridge from the abstract theoretical concepts to numerous real world problems (part 2, chapters 10-17).
Genetic Analysis of a Cryptosporidium parvum Human Genotype 1 Isolate Passaged through Different Host Species (2002)

Cryptosporidium parvum TU502, a genotype 1 isolate of human origin, was passaged through three different mammalian hosts, including humans, pigs, and calves. It was confirmed to be genotype 1 by PCR-restriction fragment length polymorphism analysis of the Cryptosporidium oocyst wall protein gene, direct sequencing of PCR fragments of the small subunit rRNA and beta-tubulin genes, and microsatellite analysis. This isolate was shown to be genetically stable when passaged through the three mammalian species, with no evidence of the emergence of new subpopulations as observed by a genotype-specific PCR assay. TU502 oocysts from different sources failed to infect gamma interferon knockout mice, a characteristic of genotype 1 isolates. The genotypic and phenotypic characterization of TU502 is significant since it is the isolate selected to sequence the genome of C. parvum genotype 1 and is currently used in several research projects including human volunteer studies.
Contribution of Multicentered Short Hydrogen Bond Arrays to Potency of Active Site-Directed Serine Protease Inhibitors (2002)

We describe and compare the pH dependencies of the potencies and of the bound structures of two inhibitor isosteres that form multicentered short hydrogen bond arrays at the active sites of trypsin, thrombin, and urokinase type plasminogen activator (urokinase or uPA) over certain ranges of pH. Depending on the pH, short hydrogen bond arrays at the active site are mediated by two waters, one in the oxyanion hole (H(2)O(oxy)) and one on the other (S2) side of the inhibitor (H(2)O(S2)), by one water (H(2)O(oxy)), or by no water. The dramatic variation in the length of the active site hydrogen bonds as a function of pH, of inhibitor, and of enzyme, along with the involvement or absence of ordered water, produces a large structural manifold of active site hydrogen bond motifs. Diverse examples of multicentered and two-centered short hydrogen bond arrays, both at and away from the active site, recently discovered in several protein crystal systems, suggest that short hydrogen bonds in proteins may be more common than has been recognized. The short hydrogen bond arrays resemble one another with respect to ionic nature, highly polar environment, multitude of associated ordinary hydrogen bonds, and disparate pK(a) values of participating groups. Comparison of structures and K(i) values of trypsin complexes at pH values where the multicentered short hydrogen bond arrays mediating inhibitor binding are present or absent indicate that these arrays have a minor effect on inhibitor potency. These features suggest little covalent nature within the short hydrogen bonds, despite their extraordinary shortness (as short as 2.0 A).
Gate‐Controlled Chiral Recognition and Spin Assessment with All‐Electric Hybrid Quantum Wire‐Based Transistors (2022)

The search for inexpensive and all-electric tunable methods for portable and fast recognition and discrimination between various chiral enantiomers, mainly those found in the gas phase, has been one of the most challenging tasks in the field of analytical chemistry. The current article reports on a chiral sensitive electric architecture (CSEA) of a helical polyaniline (PANI)@carbon nanotube (CNT) hybrid quantum-wire based field effect transistor (FET) platform. The CSEA architecture exhibits gate-controlled-channel-chirality modulation for the selective distinction of Limonene (S(+)/R(-)) at ≈12 V intervals. Typical gate-modulated selectivity of S(+)-Limonene and R(-)-Limonene using two opposite helically turned hybrids, namely as, S-PANI@CNT and R-PANI@CNT are 6.5 and 2.8, respectively. Theoretical analysis and modelling relates the gas-phase chiral quantum probe with spin-channel modulation in CNT by Rashba spin-orbit interaction. This is achieved by applied gate voltage, CNT's unique curved surface, adsorbed chiral adatom induced scattering center on the curved graphitic lattice and helicoid field from a synthetically prepared helical PANI@CNT hybrid interface.