gebhart/patrepeval huggingface dataset:
Modulus of polybutadiene networks made by hydrosilation crosslinking (1988)

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTModulus of polybutadiene networks made by hydrosilation crosslinkingMirta Ines Aranguren and Christopher W. MacoskoCite this: Macromolecules 1988, 21, 8, 2484–2491Publication Date (Print):August 1, 1988Publication History Published online1 May 2002Published inissue 1 August 1988https://pubs.acs.org/doi/10.1021/ma00186a030https://doi.org/10.1021/ma00186a030research-articleACS PublicationsRequest reuse permissionsArticle Views325Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
Resequencing Three Candidate Genes for Major Depressive Disorder in a Dutch Cohort (2013)

Major depressive disorder (MDD) is a psychiatric disorder, characterized by periods of low mood of more than two weeks, loss of interest in normally enjoyable activities and behavioral changes. MDD is a complex disorder and does not have a single genetic cause. In 2009 a genome wide association study (GWAS) was performed on the Dutch GAIN-MDD cohort. Many of the top signals of this GWAS mapped to a region spanning the gene PCLO, and the non-synonymous coding single nucleotide polymorphism (SNP) rs2522833 in the PCLO gene became genome wide significant after post-hoc analysis. We performed resequencing of PCLO, GRM7, and SLC6A4 in 50 control samples from the GAIN-MDD cohort, to detect new genomic variants. Subsequently, we genotyped these variants in the entire GAIN-MDD cohort and performed association analysis to investigate if rs2522833 is the causal variant or simply in linkage disequilibrium with a more associated variant. GRM7 and SLC6A4 are both candidate genes for MDD from literature. We aimed to gather more evidence that rs2522833 is indeed the causal variant in the GAIN-MDD cohort or to find a previously undetected common variant in either PCLO, GRM7, or SLC6A4 with a higher association in this cohort. After next generation sequencing and association analysis we excluded the possibility of an undetected common variant to be more associated. For neither PCLO nor GRM7 we found a more associated variant. For SLC6A4, we found a new SNP that showed a lower P-value (P = 0.07) than in the GAIN-MDD GWAS (P = 0.09). However, no evidence for genome-wide significance was found. Although we did not take into account rare variants, we conclude that our results provide further support for the hypothesis that the non-synonymous coding SNP rs2522833 in the PCLO gene is indeed likely to be the causal variant in the GAIN-MDD cohort.
Room Temperature Sonoelectrochemical Synthesis of Molybdenum Sulfide Fullerene‐Like Nanoparticles (1999)

Electrochemistry and sonochemistry have been combined to prepare fullerene-like structures of MoS2 at room temperature and in high yield. Either electrodeposition or ultrasonic irradiation alone results in amorphous products, whereas the application of an electric current pulse followed by a burst of ultrasonic energy gives rise to well-crystallized MoS2 structures such as the polyhedron shown in the Figure.
Formation of Elastic Cone-Like Microstructures on the Composite of Elastomer and Carbon Black by Excimer Laser Ablation (1997)

Laser ablation of composite material consisting of elastomer and carbon black was performed using a KrF excimer laser. Remarkable sensitization of polymer ablation with carbon black was observed and cone-like microstructures were produced on the ablated surface. The development of large cones was due to the aggregation of carbon-rich cones by repeated etching and melting upon further laser irradiation. The cone-like microstructures revealed a visco-elastic property that could be useful in the applications of sealing and packing materials.
Hydrogen Spillover on CeO2/Pt: Enhanced Storage of Active Hydrogen (2007)

We have investigated the concept of hydrogen spillover by a density functional theory (DFT) approach in combination with experimental observations. A H/Pt molar ratio of 5 to 9 is observed over Ce1−xPtxO2−δ catalyst, where Pt is present in the +2 ionic state. The total hydrogen adsorbed over the catalyst is ∼30 times higher than that over nano-Pt metal particles. NMR study show protonic hydrogen over the catalyst. DFT calculations indeed support the enhanced adsorption of hydrogen on the Pt-ion-doped ceria surface via spillover to the oxide support. Further, the calculations confirm the formation of protonic hydrogen on the catalyst surface in contrast to the formation of hydridic hydrogen on Pt metal.
Screening for Antifungal Endophytic Fungi Against Six Plant Pathogenic Fungi (2003)

A total of 187 endophytic fungi were isolated from 11 plant species, which were collected from 11 locations in Korea. Their antifungal activities were screened in vivo by antifungal bioassays after they were cultured in potato dextrose broth and rice solid media. Antifungal activity against plant pathogenic fungi such as Magnaporthe grisea(rice blast), Corticium sasaki(rice sheath blight), Botrytis cinerea(tomato gray mold), Phytophthora infestans(tomato late blight), Puccinia recondita(wheat leaf rust), and Blumeria graminis f. sp. hordei(barley powdery mildew) was determined in vivo by observing the inhibition of plant disease development. Twenty(11.7%) endophytic fungi fermentation broths were able to control, by more than 90%, at least one of the six plant diseases tested. Among 187 liquid broths, the F0010 strain isolated from Abies holophylla had the most potent disease control activity; it showed control values of more than 90% against five plant diseases, except for tomato late blight. On the other hand, fourteen(7.5%) solid culture extracts exhibited potent disease control values of more than 90% against one of six plant diseases. The screening results of this study strongly suggested that metabolites of plant endophytic fungi could be good potential sources for screening programs of bioactive natural products.
Anomalous Hall effect in Weyl semimetal half-Heusler compounds RPtBi (R = Gd and Nd) (2018)

Topological materials ranging from topological insulators to Weyl and Dirac semimetals form one of the most exciting current fields in condensed-matter research. Many half-Heusler compounds, RPtBi (R = rare earth), have been theoretically predicted to be topological semimetals. Among various topological attributes envisaged in RPtBi, topological surface states, chiral anomaly, and planar Hall effect have been observed experimentally. Here, we report an unusual intrinsic anomalous Hall effect (AHE) in the antiferromagnetic Heusler Weyl semimetal compounds GdPtBi and NdPtBi that is observed over a wide temperature range. In particular, GdPtBi exhibits an anomalous Hall conductivity of up to 60 Ω<sup>-1</sup>⋅cm<sup>-1</sup> and an anomalous Hall angle as large as 23%. Muon spin-resonance (μSR) studies of GdPtBi indicate a sharp antiferromagnetic transition (<i>T</i><sub>N</sub>) at 9 K without any noticeable magnetic correlations above <i>T</i><sub>N</sub> Our studies indicate that Weyl points in these half-Heuslers are induced by a magnetic field via exchange splitting of the electronic bands at or near the Fermi energy, which is the source of the chiral anomaly and the AHE.
Targeting transcription factor SALL4 in acute myeloid leukemia by interrupting its interaction with an epigenetic complex (2013)

An exciting recent approach to targeting transcription factors in cancer is to block formation of oncogenic complexes. We investigated whether interfering with the interaction of the transcription factor SALL4, which is critical for leukemic cell survival, and its epigenetic partner complex represents a novel therapeutic approach. The mechanism of SALL4 in promoting leukemogenesis is at least in part mediated by its repression of the tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN) through its interaction with a histone deacetylase (HDAC) complex. In this study, we demonstrate that a peptide can compete with SALL4 in interacting with the HDAC complex and reverse its effect on PTEN repression. Treating SALL4-expressing malignant cells with this peptide leads to cell death that can be rescued by a PTEN inhibitor. The antileukemic effect of this peptide can be confirmed on primary human leukemia cells in culture and in vivo, and is identical to that of down-regulation of SALL4 in these cells using an RNAi approach. In summary, our results demonstrate a novel peptide that can block the specific interaction between SALL4 and its epigenetic HDAC complex in regulating its target gene, PTEN. Furthermore, targeting SALL4 with this approach could be an innovative approach in treating leukemia.
ChemInform Abstract: REACTIONS OF ALKYL SUBSTITUTED BICYCLO(3.1.0)HEXATRIENE (1977)

Abstract Die Reaktivität der 2‐substituierten Titel‐Spezies (II) bzw. (V), die intermediär aus den Vorstufen (I) bzw. (IV) gebildet werden, wird untersucht: Unter den angegebenen Reaktionsbedingungen werden als Endprodukte aus (I) die isomeren Fulvene (IIIa) und (IIIb) ((3 : l),‐ (IIIb) entsteht durch Isomerisierung aus prim. gebildetem (IIIa)), aus (IV) dagegen die Verbindung (VI) und das Fulven (VII) erhalten.
Ocular Changes after Photodynamic Therapy (2005)

In a primate model, under standard clinical parameters, a single PDT treatment resulted in various dynamic morphologic and functional retinal changes detectable for up to 9 months after treatment. The significance of the observed changes and possible ways of pharmacologic interference with PDT adverse effects are discussed.
Measured savings and cost-effectiveness of conservation retrofits in commercial buildings (1990)

In this study, we examine the measured saving and cost-effectiveness of 447 commercial retrofit projects, representing over 1700 buildings. Topics include saving and cost-effectiveness by building type and retrofit strategy, savings from individual measures, peak electric demand savings, comparisons of measured vs predicted savings, the persistence of savings in the year following a retrofit, and retrofit performance by year of installation. Median annual site energy savings amounted to 20 kBtu/ft{sup 2}. Median pre-retrofit energy intensity, for all building types in the data base, was higher than that of the corresponding US stock. Changes to the HVAC system were the most popular retrofit strategy, installed in 85% to 95% of the projects in each building category (education, health, office, retail, and other). Projects in which only maintenance practices were changed typically saved 12% of their pre-retrofit consumption often using in-house labor. Projects sponsored by the Institutional Conservation Program (ICP) included more shell measures (with long payback times) and relatively fewer HVAC and lighting retrofits than projects paid for by the building owner; for the buildings in this data set, retrofits installed after 1983 had lower savings, higher costs, and longer payback times than measures installed earlier. Very few predictions of savingsmore » (about one in six) came within 20% of measured results. Over half of our projects had multiple years of post-retrofit data; energy use continued to decrease for most of these buildings. Our research suggests that, despite significant savings and short payback times for the majority of projects, savings often fall well short of economically optimum levels. 28 refs., 8 figs., 5 tabs.« less
Supplementary Methods, Supplementary Tables 1-5, Supplementary Figures 1-11, Supplementary References from Identification of CD25 as STAT5-Dependent Growth Regulator of Leukemic Stem Cells in Ph<sup>+</sup> CML (2023)

&lt;p&gt;Tables: S1 Specification of monoclonal antibodies (mAb) used in this study; S2 PatientsÂ´ characteristics - chronic myeloid leukemia (CML); S3 PatientsÂ´ characteristics - ormal/reactive BM; S4 Detection of BCR/ABL1 in sorted CML cells by FISH; S5 Major genes up-regulated by gene array analysis on KU812 cells transduced with a CD25 shRNA (KU812 CD25 shRNA, clone #2) compared to KU812 cells transduced with a random control shRNA (KU812 RDM shRNA); Figures: S1 CML LSCs co-express CD25 together with other stem cell markers; S2 Expression of BCR/ABL1 in CD34+/CD38âˆ’/CD25+ stem cells obtained from a patient with CML as determined by fluorescence in situ hybridization (FISH); S3 Clonogenic growth of CML LSCs and normal stem cells obtained from two patients with Ph+ CML; S4 Western blotting confirmed the knock-down of STAT5 in KU812 cells; S5 Drug-induced upregulation of CD25 in CML cell lines; S6 Effects of imatinib on CD25 surface expression in Ba/F3 cells expressing diverse BCR/ABL1 mutants; S7 Effects of interleukin-2 (IL-2) on growth of untreated and BEZ235-treated CML cells; S8 Effect of transduced CD25 on growth of CML cells lines; S9 Pathway analysis of KU812 cells transduced with a CD25 shRNA; S10 Effects of shRNA-induced knock-down of CD25 on cell cycle progression and apoptosis in KU812 cells; S11 Effects of shRNA-induced knock-down of CD25 on the responsiveness of KU812 cells to imatinib, nilotinib, ponatinib and BEZ235.&lt;/p&gt;
Towards circuit design using VeSFETs (2011)

This paper explores the potential of VeFETs for mixed-signal circuits. A new physics-based compact DC model of the VeSFET operated in subthreshold region is presented and used to derive 1st-order sensitivities of the device threshold voltage to process variations. The VeSFET is compared to the MOSFET transistor, and its advantages and limitations are discussed. Using a Sea-of-Gates-like structure, layout strategies for area-efficient implementation of digital and analog functions are proposed. Finally, the implementation of a mixed-signal circuit (an OTA with chopper modulation) is presented to demonstrate the area-efficiency of circuit implemented with Sea-of-Gates VeSFETs. Â© 2011 Tech Univ of Lodz
Repository simulation tests (1984)

The repository simulation experiments described in this paper are designed to assess the performance of SRP waste glass under the most realistic repository conditions that can be obtained in the laboratory. These tests simulate the repository environment as closely as possible and introduce systematically the variability of the geology, groundwater chemistry, and waste package components during the leaching of the waste glass. The tests evaluate waste form performance under site-specific conditions, which differ for each of the geologic repositories under consideration. Data from these experiments will aid in the development of a realistic source term that can describe the release of radionuclides from SRP waste glass as a component of proposed waste packages. Hence, this information can be useful to optimize waste package design for SRP waste glass and to provide data for predicting long-term performance and subsequent conformance to regulations. The repository simulation tests also help to bridge the gap in interpreting results derived from tests performed under the control of the laboratory to the uncertainity and variability of field tests. In these experiments, site-specific repository components and conditions are emphasized and only the site specific materials contact the waste forms. An important feature of these tests is that both actual and simulated waste glasses are tested identically. 7 figures, 2 tables.
Nanospectroscopy of Infrared Phonon Resonance Enables Local Quantification of Electronic Properties in Doped SrTiO3 Ceramics (2018)

Abstract Among the novel materials for electronic applications and novel device concepts beyond classical Si‐based CMOS technology, SrTiO 3 represents a prototype role model for functional oxide materials: It enables resistive switching, but can also form a 2D electron gas at its interface and thus enables tunable transistors. However, the interplay between charge carriers and defects in SrTiO 3 is still under debate. Infrared spectroscopy offers the possibility to characterize structural and electronic properties of SrTiO 3 in operando, but is hampered by the diffraction‐limited resolution. To overcome this limitation and obtain nanoscale IR spectra of donor‐doped Sr 1‐x La x TiO 3 ceramics, scattering‐type scanning near‐field optical microscopy is applied. By exploiting plasmon–phonon coupling, the local electronic properties of doped SrTiO 3 are quantified from a detailed spectroscopic analysis in the spectral range of the near‐field ‘phonon resonance’. Single crystal‐like mobility, an increase in charge carrier density N and an increase in ε ∞ at grain boundaries ( µ ≈ 5.7 cm 2 V −1 s −1 , N = 7.1 × 10 19 cm −3 , and ε ∞ = 7.7) and local defects ( µ ≈ 5.4 cm 2 V −1 s −1 , N = 1.3 × 10 20 cm −3 , and ε ∞ = 8.8) are found. In future, subsurface quantification of defects and free charge carriers at interfaces and filaments in SrTiO 3 can be envisioned.
Optical fiber and microwave wireless up-links using EO modulator with planar stripline feed to gap-embedded patch-antennas (2017)

Microwave wireless and optical fiber technologies are widely used for several applications in communication, sensing, imaging, and so on. We propose an electro-optic (EO) modulator with a planar stripline feed to a gap-embedded patch-antenna for hybrid uplinks to an optical fiber and microwave wireless networks. The proposed device is designed on an EO crystal with simple and compact structure. The gap-embedded patch-antenna on the EO modulator can be operated for optical modulation to the optical fiber network. The proposed device can be also operated for microwave transmission to the air or wireless networks. Characteristic and analysis of the designed device for optical modulation and wireless microwave transmission are reported and discussed.
718: The P21 Growth and Apoptosis Regulatory Protein is an Independent Predictor of Survival in Patients with Clear Cell Renal Cell Carcinoma (2006)

You have accessJournal of UrologyDiscussed Poster, Monday, May 22, 2006, 1:00 - 4:00 pm1 Apr 2006718: The P21 Growth and Apoptosis Regulatory Protein is an Independent Predictor of Survival in Patients with Clear Cell Renal Cell Carcinoma Robert H. Weiss, Alexander D. Borowsky, David B. Seligson, Pei-Yin Lin, John S. Lam, Arie S. Belldegrun, Robert A. Figlin, and Allan J. Pantuck Robert H. WeissRobert H. Weiss More articles by this author , Alexander D. BorowskyAlexander D. Borowsky More articles by this author , David B. SeligsonDavid B. Seligson More articles by this author , Pei-Yin LinPei-Yin Lin More articles by this author , John S. LamJohn S. Lam More articles by this author , Arie S. BelldegrunArie S. Belldegrun More articles by this author , Robert A. FiglinRobert A. Figlin More articles by this author , and Allan J. PantuckAllan J. Pantuck More articles by this author View All Author Informationhttps://doi.org/10.1016/S0022-5347(18)32954-9AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail "718: The P21 Growth and Apoptosis Regulatory Protein is an Independent Predictor of Survival in Patients with Clear Cell Renal Cell Carcinoma." The Journal of Urology, 175(4S), p. 232 © 2016 by American Urological AssociationFiguresReferencesRelatedDetails Volume 175Issue 4SApril 2006Page: 232 Advertisement Copyright & Permissions© 2016 by American Urological AssociationMetricsAuthor Information Robert H. Weiss More articles by this author Alexander D. Borowsky More articles by this author David B. Seligson More articles by this author Pei-Yin Lin More articles by this author John S. Lam More articles by this author Arie S. Belldegrun More articles by this author Robert A. Figlin More articles by this author Allan J. Pantuck More articles by this author Expand All Advertisement PDF DownloadLoading ...
<title>Ultrathin organic films for field effect transistors</title> (2001)

Organic field effect transistors FET have been fabricated with active semiconducting organic thin films that are only a few monolayers thick. The motivation of this study has been to establish a direct correlation between transistor performance and the polymer microstructure in the ultrathin accumulation layer of the transistor. Monolayer thick films of a block copolymer and several model oligomers consisting of a rigid conjugated sexithiophene (6T) block and a flexible polyethyleneoxide (PEO) block have been deposited onto the surface of e.g. SiO<SUB>2</SUB> gate dielectrics functionalized with a self-assembled monolayer. Block copolymer phase behavior and surface morphology has been studied as a function of chain length, solvent and film thickness. Operational transistors have been demonstrated with film thicknesses of only one or two monolayers. Typical device characteristics show a carrier mobility on the order of 10<SUP>-2</SUP> - 10<SUP>-3</SUP> cm<SUP>2</SUP>/Vs and ON-OFF current ratio of 10<SUP>3</SUP> - 10<SUP>5</SUP>. Film microstructure, orientation of micro-crystallites and film thickness have been studied by atomic force microscopy (AFM), UV-Vis absorption spectroscopy and X-ray diffraction.
MEMS Heart Sound Sensor (2015)

In this research, we fabricated a MEMS (Micro Electro Mechanical Systems) heart sound sensor (phonocardiogram sensor). The sensor is based on piezo-resistive silicon cantilever and it detects the skin vibration caused by heartbeat. We made a small water chamber between the cantilever and the skin, so that good impedance matching between the skin and the cantilever was achieved. We measured the heart sound by the MEMS heart sound sensor and the commercial electronic stethoscope simultaneously and comparing the outputs. As a result, we confirmed that our MEMS heart sound sensor can detect the heartbeat as same as electronic stethoscope.
α-Conotoxins ImI and ImII (2003)

A novel conotoxin, alpha-conotoxin ImII (alpha-CTx ImII), identified from Conus imperialis venom ducts, was chemically synthesized. A previously characterized C. imperialis conotoxin, alpha-conotoxin ImI (alpha-CTx ImI), is closely related; 9 of 12 amino acids are identical. Both alpha-CTx ImII and alpha-CTx ImI functionally inhibit heterologously expressed rat alpha7 nAChRs with similar IC(50) values. Furthermore, the biological activities of intracranially applied alpha-CTx ImI and alpha-CTx ImII are similar over the same dosage range, and are consistent with alpha7 nAChR inhibition. However, unlike alpha-CTx ImI, alpha-CTx ImII was not able to block the binding of alpha-bungarotoxin to alpha7 nAChRs. alpha-Conotoxin ImI and alpha-bungarotoxin-binding sites have been well characterized as overlapping and located at the cleft between adjacent nAChR subunits. Because alpha-CTx ImI and alpha-CTx ImII share extensive sequence homology, the inability of alpha-CTx ImII to compete with alpha-BgTx is surprising. Furthermore, functional studies in oocytes indicate that there is no overlap between functional binding sites of alpha-CTx ImI and alpha-CTx ImII. Like alpha-CTx ImI, the block by alpha-CTx ImII is voltage-independent. Thus, alpha-CTx ImII represents a probe for a novel antagonist binding site, or microsite, on the alpha7 nAChR.